(From gene tree: ENSGT00530000063191)
Query using REST API:
http://54.147.54.166:8080/domainid?domain=ENSGT00530000063191_Domain_1QQPPYSKCFE-DHLEQKYVQLFSGLPS-LHSKSLNPTVL-LPRGRSS-----MSVSFNEIAS----------------MSAL----QKSPVLPHP----QSLS---------LPITQ-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLLQGQ----SV--------AQHL-----SPLTAQVPSPPLLDLQIG-----ICRVCFHKY-QNEALSLTPSEI------------------------------------------------NHLERNV------LQKVLE---SVWGLPSVVQKSQEYFCSPAPRLALV-K-----PFKACGPISII--PGDFALSAEVRKKLEHHLKKRLIQHR-----WGL-PRRV-HECLTLLRPQSLI-------------------SE---S-E--NSQQPPYSTNLEEGHLQQTSIQLFWGLPT-LHSESLSSAAR-DSDDCSS-----IFI-FSRISN----------------TSTG----QESPVVPHP----SPLP---------LPENQ-S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPIPQIQPQIHLK-----SPLPILPSGPL---PQIK-----ICGVCFHRP-QHKSEPLLSSEM------------------------------------------------QRLEWNV------LQKQQE---SVWGLPPVVQRSNKDFCPSAPDRSIKRP-----AFQARVAISIL--PGQFPLSEELRKELEHHLRKRLIQHR-----WGL-PRRI-YESVSLMMPPSDS-------------------SETPKC-Q--RFRG----RTW------------------ISKSHSNLS------------E-SESY----EQDSELLQ-LRNIDM--GKDQGHNPGSG--------PKDHLLS----Q---NSSD-NDLGY-DSEKEFRS------------PSEKNP------MSLDTAGQ-RQLENVLKIHLSK-KFEEINEGRLP-GTVHNSIR-E-ETPSFISTAI------------------------------------------------QNLECHF------LKKQLE---RDRTLPAVVKRSQEVFNQVSPNFLQDDQ-----DPEAHESISVL--PE-DLISPELREQLEWHLWKRFMRH--Q---SGL-PHKI-QLSVKLIQPQDEA-------------------LKVTQA-H--SQRR-----PM-W----------------PSASRDRSCQAVQK---TGSRN-PAR--------TMP---G--KKL--GKDTRSSVRKI---------QKDLCR----GS-STSPW-KEPGK-GSE-ESDPDMMKR--------------------STSSQDK-KHPEKILRTHLGR-KLGQIREGQIP-VDVHRSQQLSYPKVLG-HPLQHKYNQLFWGLPS-LHSESLVATAW-ISESSSAL---QSPFLFNGISN----------------TCPVQMQAK--SLLSQS----KPLS---------QLEFQ-SQPLS-TTP--QFQPP-PLAQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILTQEHLQ-----SSLPILSPSSS---PQIM-----ACKISSPTA-QDKSQFLIPTEI------------------------------------------------QHPEWPL------LQEQLE---SGWALSSVIKGSQEVFSVFTSNLPEDSL-----V------VSIL--PENFPISPELRKQLEQHLQKWLIQHH-----WEL-PRKIQ-ESLELRQLQGEL-------------------PGTCQA-K--GKHR-----PS-Q----------------PSAFIGKSSKDTQK---VGF-----------QMSQGM---G--K------GLGYILGKV--------PK-EFSR----NA-ESSLM-RFQGV-GSEES-ES---------DVGLSKSDSESD----LLRSLD--KNLENILKGHLGR-KLGHVSEGLIP-ESAHQSQPPYPTTLEEGHLQQTPIQLFWGLPT-LHSESLSSAAC-DSDDCSS-----ILI-FSRISN----------------TSTG----QESPVVPHP----FPLP---------LPENQ-S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPIPQIQPQTHLK-----SPLPLLPSGPL---PQIK-----ICGVCFHRQQLSSPKILE-DHLQQKCSQLFWGLPS-LHSESLLATAL-VCTHSPQL--QVPFLLFNGLSN----------------CLPALIQVFISSQFSHV----SSLP---------HHGIQ-LQPSTPIWPQ--PQAH------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-----PSVPIRPPSLP---PQMS-----ACGVPCPAS-QEKTQFFIPNET------------------------------------------------QQLEWPL------LPKHQE---RGRTLHYMMKRYRKFFGKVPPKLPKYNQ-----DSQSYGSVSII--HG-DFVIFNIQKHHHQ--RRLS-KDKHR---DSL-PHRV-QVSLELMWPPNEF-------------------PETSKA-Q--DNQG-----FS-R----------------PFVFKGKSSQTTQR---TKSRD-PRSFYRKSQTRSQL---Q--NNL--GNGLQQCLKRS---------PTDLSR----VS-ASFPV-KVLGT-DSEEELERHLMRTL--------KSDQGKH----LARGPGK-KHLEKNLEVHLCR-KLGQINEGLIP-VSVRRSQEPPYSKCFE-DHLEQKYVQLFWGLPS-LRSESLHPTVL-VQRGHSS-----MFVFFNGITN----------------TSLF----QESPVLPPP----QPLS---------LLSTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLPQTLPQGQ----SPHLTEVQSQAQHQ-----SPLPALLPSPP---FLIK-----ICGVCFHRP-QNEARSLTPSEI------------------------------------------------NHLEYN------------E---SVWGLPSVVQKSQEDFCPPAPNLALVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQHR-----WGL-PHRI-HESLSLLRPQSKI-------------------SEQSAS-E--TIQG----PLH------------------SSSVEGQSLNVLKK---FGSST-PRTFHERSSNMLSL------ENV--GNYQGYRQENG--------PKNYLLH----DP-KTSSD-ENPRS-NSERDLNTH--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQQVSDATAVG-DHLQQKCSQLFWDLPS-FNSESLVATAC-VSSKPSSP--NAHSVSLDKAST----------------PLPGEPEVEASSQLSQA----PPQP---------HHMAQ-PQPFTPAWPQ--SQPP-PLAGIQTQ-AHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-----PPVPSLPWSSP---PQIR-----DCGASYHTT-QERTQSVIPAGK------------------------------------------------ENLEWTL------KKG-PK---WKRVLPSLLKKSPAVLSQPTAYRPHERP-----ASWSPKSAPIL--PG-VATSPELPEHRWQ-GRSAI-HQEQS---CGP-PSRF-QASGDLLQPEGEF-------------------PGRPQS-Q--AEDTQQALLPS-Q----------------PSEFAREGRKDVQK---TGFRS-SGR-----------------------FSGKGCLRSK---------PGPDPSQDP-GL-GRTSV-KFLE--EDKEEAEGDIQ--------RPWKYQSVSS----TPGDPDK-KHLENKLQIHLAR-KVGEIKEGWIP-VPVRRSQKLSDPRILQ-ESFQKNYSQLFWGLPS-LHSESLVANAW-VTERSYTL--QSPPFLFNGISN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----SIPMAQ----AHLQ-----SSFPVLSPAFP---SPIN-----NSGVACPAS-QNKLQALCLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKFQDVFSVSTPNLPQESL------------PSIL--PENFPISPEVRRQLEQHIQKWFIQH------QGN-LGRI-QESLDLMQLRDES-------------------SGTSQV-K--GEPR-----PW-Q----------------SSTSTGKSSKEAQK---VK---------------FQ-----LERDP--CPHLEQILGQT---------PQNLSR----GM-ESFPG-KVLGA-TSE-ELERDLR--------KPLRSDSG-----------KR-NRIENVLKAHVGR-KLGQMNEGLIP-VSVHRSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPNVL-VQRGHSS-----MFVFFNGITN----------------TSIF----QKSPVLPPP----QPLS---------LPNTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLTQGQ----SPHLTEVQSQAQHQ-----SPLPALLPSPP---FLIK-----ICGVCFHRP-QNEAQSLTPSEI------------------------------------------------NHLECNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNLTLVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIQG----PLH------------------SSSVEGQSLNVPKK---FGSST-PRTFHERSSNMLSL------ENV--GNFQGYRQETG--------PKNYLLH----DP-ETSSD-ENPRS-NSERDLNTH--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQEPPYSKCFE-DHFEQKYVQLFWGLPS-LHSESLHPTVL-GQRGRNS-----MFVFFNGITN----------------ISRF----HKFPVLPSP----QPLS---------LPNTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVQSQAQHQ-----SPLPVLLPSPL---FLIR-----ICGVCFHRP-QNEAQSLTPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------RSSVEGQSLNVLKK---FGSII-PRTLHERSSNMLSL------ENV--GNYQGCSQETG--------PKNHLLQ----DP-ETSSD-EDLRS-NSERDLDTH--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQQVSDATAVG-NHLQQKCSQLFWNLPS-FS-ESLVATAW-VSSKPSSQ--NAHSVSLDEAST----------------SLPGEPEVEVSSELSQA----PPSS---------QNAHS-V--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLD------EAST--------------------S------------------------------------------------------------------------------LP---GG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------P--------------------------E-----------------------------------------------------------------------VE-------------------------------------------------------------------------------------------------------------------------------------------------------ASAQLSQ------------------AATWT-CS----LPQ-----------QEPPYSKCFE-DHFEQKYVQLFWGLPS-LHSESLHPTVL-VKHGRSS-----MFVFFNGITN----------------TSIS----QESQVLPPP----QPLS---------LPSTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVQSQAQHQ-----SPLPALLPGPL---FQIR-----ICGVCFHRP-QNEAQFLTPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALARK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------SSSVESQSLNVLKK---FGSST-PRTFHERSSNMLSL------ENV--GNYQGYRQENG--------PKNHLLH----DK-ETSSD-EDPRS-NSERDLDTH--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQKLSDPRILK-EHFQKNYSQLFWGLPS-LHSESLVANAW-VSERSCTL--QSPPFLFNGIPN----------------VRPVQTETTMSPLLFQA----QHLS---------HLRPE-SQPFISP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFQ----LSPMAQAEAQARLQ-----SSFPVQSPAFA---SSIN-----NSGVACPAS-QNKAQALTLPEM------------------------------------------------QCPEWS--------SKQLE---GGLALPSRAQKPQDVFSVSTPNLPQDSL------------TAIV--PESFPVSPELRRQLEQHIQKWLIQH------RSN-LGMT-QESPDLMQPQEKL-------------------PGTSQA-G--GKLR-----PL-Q----------------SSMSTGESSKDIQK---VM---------------FQ-----LERNP--CTPLG----QT---------PQNLAR----CM-ESFPG-NILGA-ASE-ELERDLK--------MSLRKDSESD----LLRRTER-NCIKNILKAHVGM-KLGQINEGLIP-ICVRRSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLNPTVL-LHRGRSS-----MFVFFNEIAS----------------MSTF----QEPPVLPHP----QPLS---------LPITQ-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SL--------AQHP-----SLPTAQLPSPL---FQIG-----ICGVCFHKS-QNEGQSLTPSEI------------------------------------------------NHLEWNV------LQKLLE---SVWGLPSVVKKSQEDFCSPAPSLALV-K-----SFKACDPIPIS--TGDFPLSTELRKKLEQHLRKRLIQHR-----WGL-PRRI-HESLSLLRPQSPI-------------------LEISES-E--NSEG----PLH------------------SSLVEGQSHNDLKN---FKSRK-RRSFHKRSSNMLSL------ENV--GKLQGYSQENG--------PKGDLLH----EP-ETSSE-EDLSS-NSESDPEGH--------MMHLPGNDL--------GVSLGQ-KQLANALTVHLSK-KFEEISKGQVP-WSVRSSQQPPYSKCFE-DHLEQKYVRLFWGLPS-LHSESLNPTVL-LHRGRSS-----MFVFFNEIAS----------------MSAF----QEPPVLPHP----QPLS---------LPITQ-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SL--------AQHP-----SLPTAQLPSPL---FQIG-----ICGVCFHKS-QNEGQSLTPSEI------------------------------------------------NHLEWNV------LQKDQE---SVWGLPSVVKKSQEDFCSPVPSLTLV-K-----SFKACDPIPIS--TGDFPLSTELRKKLEQHLRKRLIQHR-----WGL-PRRI-HESLSLLRPQSPI-------------------LEISES-E--NSEG----PLH------------------SSLVEGQSHNDLKN---FKSRK-PRGFHKRSSNMLSL------ENV--GKLQGYSQENG--------PKGDLLH----EP-ETSSE-EDLSS-NSESDLEGH--------MMHLPGNDL--------GVSLGQ-KQLANALTVHLSK-KFEEINEGRVP-GNVCSSQKLSDPRILK-EHFQKNYSQLFWGLPS-LHSESLVANAW-VSERSYTL--QSPPFLFNGIPN----------------VRPVQTETIISPLLFQA----QHLS---------HLRPE-SQPFISP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFQ----LSPMAQAQAQARLQ-----SSFPVQSPAFA---SPIN-----NSGVACPAS-QNKAQALTLPEM------------------------------------------------QCPEWS--------SKQLE---GGLALPSRAQKPQDVFSISTPNLPQDSL------------TAIV--PESFPVSPELRRQLEQHIQK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------C-NQQVSDATAMG-DHFQQKCSQLLWDLPS-FNSESLVAAAW-VSKASS---GNRHRVSFCEAAT----------------SLPREPEVEASSQIPQA----PPQP---------HHVAQ-PQLVTPARPQPQPQPP-PLAGIQTQ-AHF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-----PRVPSLPFSSP---PHIR-----GCGASCLTS-QQRAHSAIPTGK------------------------------------------------GYLEWPL------QKR-PK---WKRVLPSLLQKSQAVLSEPTAHLLQERP-----APYSAKSAPIL--SG-AASSPELPEHQWR-GKGAI-HQEQP---RGS-PGRF-QPPGDPLRPQGEF-------------------PGMPQH-Q--AEDMQGTHLPS-Q----------------PSEFSGKHSEDGQK---TGFRS-SGR-----------------------FSGKGCLRSK---------QEPDPSQDRGGS-GRTSV-KLLE--EDKQEAEGDFR--------RPWKNQSVSS----APGHPDK-KHPENKLQVHLGR-KVGEIKDGWIP-MPVRRSQKLSYPKILG-DHFQQKYKQLFWGLPS-LHSESLVAAAW-ISQTSSTL--PSPFFLFNVISS----------------VYPIQMQDKMSSVLSHT----HPLS---------YLDLQ-SPPLILSPP--QFQPP-VLNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHLQSPLP-----ALLPSPL-PYT------R-----DYGTSCSQS-QSKPQC-LPTEA------------------------------------------------QYRERPS------LAKQPE---SRLAFPLMDQRPQKVYDVLAPDLSQD-L-----A------VSIL--PDNFPISSELREKLEQHIQKWLIQHR-----WDL-PRKIQ-ESLDVMQFQNIV-------------------TATCQT-R--DKPG-----CS-Q----------------PFVSVGEHSKDGQK---VRF---------------QL---E--KES--GKNLGPILGKI--------SK-DPIR----YL-QQSHHLRTSE-DQLEPNHIQFFWGLPS-LHSESMNSIAT-VWVDSSL-----ISGCFN--------------------------RFSDSPVLTNH----IPLS---------LPESQ-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLPQILSLSQ----SQPVPPAKPQ--LQ-----HPIPVLSPFSQ---SQIR-----ICEGVFSQT-QDKVQPLESSEI------------------------------------------------HCLNYNI------LKKELE---RVWGLPTVVKKSQEEFFPPPPKPSLVKQ-----SFKTHVLKSIS--LGNFLLTSDLRKKLENHLRKRLILQH-----WGL-SKRI-YKSLPWVNPLAEL-------------------PETSSS-T--INYE----LSW------------------LSFFKQQGSKDLHN---SVLNK-PGSFPARQS--------A-EKLF--KAR-AHSTETI--------KKHQLWS----NT-KGTLD-NGLQS-NCEAILHHH--------PGSLSGKPSG-----TSQVSQHR-ENLETALQKHLAR-----------------QQGLAQAQISE-DQLEPKPTQHFWGLPY-LHSESVHTITT-LSAHCSS-----TCIWFN--------------------------RIPDSSALTHP----TPLS---------LPGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSQ----SQGVLLNTSQTQLQ-----PAIPMPPSSSQ---SQIT-----ICEVYFHRS-QGETKALLQSEI------------------------------------------------HL-----------LTKGQE---RAWSLPSVVQKSQEKFCLLPSKPSLVRR-----SSKTHAPKSVP--SGNFPLTDAFRKKLENHLRKRLILQR-----WGL-SERI-FKSQPWMNPDPE-----------------------ESS-M--SNHG----LSQ------------------VSVFQHQDSKD-PH--NTVSNQ-PGSSQERCSESQSL---E-KKME--KTQ-GQNSEAV--------QR-NLWD----NS-KGALD-NGLQS-DCQKNPQCH--------SSSLSGKPSG-----TSQVSQYR-KKLETALQKHLTR-NLNETNKGQIS-DTRSRTIQG-RGLGQKHSQLFWGLPS-LHSESIVATLLVLPLNSYSL--EPQLMLFNGVCR----------------AVTAPVLGYGCPAPPQP----HT-------------------PQPQPLSNA--EPQ-PQTLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FTQ----AHVQ-----SALAPLQ-SPS---LPCG--------SPPQMP-QDSTVSGVVHGN------------------------------------------------KDLQCHS------LENHQH---SLWGLVPKSQQYGTPFGLLVPSLPLVSQ-----PSQNYASVP-R--TGHFHSGSELQGNLESYGPNNPIPPW-----CYP---------------QFKT-------------------TETSPH-S--CKCV-----KP-Q----------------RTVHWDQSCSNLRT---GEL-----SFYETVSMKPQL---R--QDV--AKNLGQILGRC--------PLGNPQM----IS-GCYIL-NNLRV-IPET--QMEWA--------CHSGVGLEHEGDGISRKSLDQ-RQTRSILRLHISR-KLWQITMGRIP-IKVCCSCK---------------------------------------------DQLEPNHIQFFWGLPS-LHSESMNSIAT-VWVDSSL-----ISGCFN--------------------------RFSDSPVLTNH----IPLS---------LPESQ-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLPQILSLSQ----SQPVPPAKPQ--LQ-----HPIPVLSPFSQ---SQIR-----ICEGVFSQT-QDKVQPLESSEI------------------------------------------------HCLNYNI------LKKELE---RVWGLPTVVKKSQEEFFPPPPKPSLVKQ-----SFKTHVLKSIS--LGNFLLTSELRKKLENHLRKRLILQH-----WGL-SKRI-YKSLPWVNPLAEL-------------------PETSSS-T--INYE----LSW------------------LSFFKQQGSKDLHN---SVLNK-PGSFPARQS--------A-EKLF--KAR-AHSTETI--------KKHQLWS----NT-KGTLD-NGLQS-NCEAILHHH--------PGSLSGKPSG-----TSQVSQRQ-ENLETALQKHLAR-----------------QQGLAQAQISE-DQLEPKPTQHFWGLPY-LHSESVHTITT-LSAHCSS-----TCIWFN--------------------------RIPDSSALTHP----TPLS---------LPGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSQ----SQGVLLNTSQTQLQ-----PAIPMPPSSSQ---SQIT-----ICEVYFHRS-QGETKALLQSEI------------------------------------------------HL-----------LTKGQE---RAWSLPSVVQKSQEKFCLLPSKPSLVRR-----SSKTHAPKSVP--SGNFPLTDAFRKKLENHLRKRLILQR-----WGL-SERI-FKSQPWMNPDPE-----------------------ESS-M--SNHG----LSQ------------------VSVFQHQDSKD-PH--NTVSNQ-PGSSQERCSESQSL---E-KKME--KTQ-GQNSEAV--------QR-NLWD----NS-KGALD-NGLQS-DCQKNPQCH--------SSSLSGKPSG-----TSQVSQYR-KKLETALQKHLTR-NLNETNKGQIS-DTRSRTIQG-RGLGQKHSQLFWGLPS-LHSESIVATLLVLPLNSYSL--EPQLMLFNGVCR----------------AVTAPVLGYGCPAPPQP----HTV---------PLTFLH-PQPQPQPQPQP--QPQ-PQPQP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSN----AHVQ-----SALAPLQ-SPS---LPCG--------SPPQMP-QDSTVSGVVHGN------------------------------------------------KDLQCHS------LENHQH---SLWGLVPKSQQYGTPFGLLVPSLPLVSQ-----PSQNYASVP-R--TGHFHSGSELQGNLESYGPNNPIPPW-----CYP---------------QFKT-------------------TETSPH-S--CKCV-----KP-Q----------------RTVHWDQSCSNLRT---GEL-----SFYETVSMKPQL---R--QDV--AKNLGQILGRC--------PLGNPQM----IS-GCYIL-NNLRV-IPET--QMEWA--------CHSGVGLEHEGDGISRKSLDQ-RQTRSILRLHISR-KLWQITMGRIP-IKVCCSQKLSYPKILG-DHFQQKYKQLFWGLPS-LHSESLVAAAW-ISQTSSTL--PSPFFLFNVISS----------------VYPIQMQDKMSSVLSHT----HPLS---------YLDLQ-SPPLILSPP--QFQPP-VLNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHLQSPLP-----ALLPSPL-PYT------R-----DYGTSCSQS-QSKPQC-LPTEA------------------------------------------------QYRERPS------LAKQPE---SRLAFPLMDQRPQKVYDVLAPDLSQD-L-----A------VSIL--PDNFPISSELREKLEQHIQKWLIQHR-----WDL-PRKIQ-ESLDVMQFQNIV-------------------TATCQT-R--DKPG-----CS-Q----------------PFVSVGEHSKDGQK---VRF---------------QL---E--KES--GKNLGPILGKI--------SK-DPIR----YL-QQPPYPKTVE-DQLQQKPTQLFWGLPS-LHSESLPSAVH-VSSDSSS-----NFI-FNRNSN----------------ASTG----QESPGLPHP----QPQF---------LPEIQ-PE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQSQ----PLPLTQVQSQADPK-----SPLLVTPPGPL---PQVR-----ICGVYFHRP-QNESESLSSSEI------------------------------------------------QQLEWNV------LQKQQE---SLWGLPSVIQRSQEAFCPLAPNTSHHQH------PQAHVSVSIL--PGEFALSDELRKKLEHHLRKRLIQHR-----WGL-PRRI-KESVSLMLPPDGF-------------------LEASKS-E--SSDG----VSL------------------ISVFKGQSSKHV-S---VELIQ-PGSFRERSSEML-----QLEKDV--GKDQEHSQENG--------QEDHLLK----DP-NSSSN-KDLGY-DSEKNINSQ--------IVSLSEKNLR-----GSAESL----QLENVLKVHLSK-KFEEINEGRLP-GTVHSSQPSPRAHMETQVQPLPVTPIMPQCQ----PSPRFQLEATAHMS-----PSLPIQPSSSK---PQIR-----YGEVSYATA-QSKGQTSVPNAI------------------------------------------------QNLEHHF------LIKQLE---SRKIIPSLVKRYQHAFSQVTHNHSQESR-----PSQAHISVTTP--FG-DLIRPEVWEKLDHHLSKRFMQQ--Q---SDL-PCRI-QASQKVMQTQGKF-------------------PKLCQV-Q--AKKG-----PS-I----------------PSAVLGKSSQDTQK---MRSRS-SAR--------IPP---E--KDL--CQDIEQSVGKI---------VKDLYM----IS-ANTTV-KVPRV-KPE--SQ--------------------------REQQLLHPESLR-DHIEQKCSQLFWGLPS-LHSESLVAAAL-IPESSSQS--QAPFILFNGISN----------------VFPVSIQPGIPLSLSQD----PLLP---------CAGAQ-PQPFTQNLPM--YQPP-SMVQIQGQ-PYL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-----SPLLFRPTYSS---PQVS-----TCGLYYLPF-QNNPLYLTPTET------------------------------------------------QSLEYPL------LQKQLK---TEMPLPSVNKRSQEVFSQLIPNCPQDTG-----EPQAQRLVPGP--HG-DLIKSDLQKQHLQ--KKPM-EDQLK---GRQ-LRSI-HLSLQLSSSQCQF-------------------LVTYQA-Q--GKQG-----SW-Q----------------LTAFRGKRSQDTQK---TRSKC-PRRSHRRSQMKFQL---E--TDF--SEGLRPCLRGI---------LKDPSR----S---SFLK-KFLQT-NSEKESERYLLRPSKSDLLRPSKSDSRNY----LLGGPEK-KHLEKVLKAHLDK-KLRQIDQGLIP-VTVRRSQQLLYVKTLG-GNLQQKYSQLFWGLPS-LHSESLVATLL-VSSSSSPP--ESHFVLFNGICN----------------APAAKMRDQESPPLLHS----RPRL---------LPHVYPPQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CLPQTKPQSQ----SLPFTQVQAQAHLQ-----ARLPMLSSSSP---SQIR-----DCGVSFHRF-QNESDFHIATEN------------------------------------------------QHLEWHV------LQKQQE---SLWGLVPVLQKSQ-VTCSQAHNVPLVNQ-----PSHAYVPVSIL--PGHFHITSEPQEKLELHVPRRLNPRW-----YLQ-ACRN-LESLALMGPQCKL-------------------AEVPQQ-R--GRHV----QLQ------------------HSKLQGQGSNNIEK---TELGL-PGNFQEKVSTKFQL---R--DDM--RKNLGYILEKS--------PEDSPQD----VS-ECYLV-QGLRA-AL--ETKTN--------CVFQSRNHSRNELLNVSRKDIDR-NQIKNILRLHVSM-KSWQISVGRIP-TGVCRSQQFSYPKVLG-NNLQQKCNQLFWGLPS-LHSESLVAAVS-IPETSSVP---QSPFLFNRISH----------------ACPVQMQAKISPLLFQF----QPFS---------HLEFQ-SQPFIPTIP--QFQPP-PLAQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQTQAHLK-----SSLPILPSSSS---AQIR-----TFGLSCPTA-QNKPQSLTPTEI------------------------------------------------QHSEWSL------LQKQLE---NGRTLSSVVKQSEEVFNVFPSNLPEDSW-----V------VSIL--PENFPISLELRKQLEQHLQNWLIQHQ-----WEL-PQRIQ-ESSEIRQLQGEL-------------------PSTCQA-K--GKDR-----PP-Q----------------PSLFTGKSSKDAQK---VRF-----------QLSQGV---G--K------GLGHILGKV--------PK-DLSR----NS-ESSVV-KFQEV-NSEES-EN---------DLRLLRSDSGID----LLRSLD--KNLDNILKGHLGR-KLGRNSKGLVP-VNVHQLCQPSSRAHMEIQARPQSLTPVIPLYH----PRPQAQFETTVHPS-----PSRLVQSSSSQ---HQIG-----STETSCPTV-QNKASSFSSNAI------------------------------------------------ENLESHF------RKKQLE---RERTLPSLVTNSQQVFSQVTPNLPQETR-----SSQAHRSVSVL--PG-YLISPEVREKLEHHISQRFMQQ--Q---SGL-PYRI-QASQKLMQPQDQY-------------------PRPCQA-Q--GREG-----PS-R----------------CSAGLGKRRQDAQK---MRSKC-PAQ--------IVP---G--RDL--HHDVGQSVGKI---------AKHLYM----FS-ANPPV-EDPRA-KSE--SE--------------------------RVLSPDK-KHPAVSS-VLTER-KGKQICEREIL-VKVYHSQQPPYPKTVE-DQLQQKPTQLFWGLPS-LHSESLPSAVH-VSSDSSS-----NFI-FNRNSN----------------ASTG----QESPGLPHP----QPLS---------LPEIQ-PE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQSQ----PLPLTQVQSQADPK-----SPLLVTPPGPL---PQVR-----ICGVYFHRP-QNESESLSSSEI------------------------------------------------QQLEWNV------LQKQQE---SLWGLPSVIQRSQEAFCPLAPNTSHHQH------PQAHVSVSIL--PGEFALSDELRKKLEHHLRKRLIQHR-----WGL-PRRI-KESVSLMLPPDGF-------------------LEASKS-E--SSDG----VSL------------------ISVFKGQSSKHV-S---VELIQ-PGSFRERSSEML-----QLEKDV--GKDQEHSQENG--------QEDHLLK----DP-NSSSD-KDLGY-DSEKNINSQ--------IVSLSEKNLR-----GSAESL----QLENVLKVHLSK-KFEEINEGRLP-GTVHSS-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PFPQTLPQGQ----SP--------AQNP-----SPLTAQPPSPL---FQIG-----ICGVCFHKS-QNEAQSLTPSEI------------------------------------------------NHLEWNV------LQKILE---SEWGLPSVVQKSQEDFCSPAPSLAFV-K-----SFKARGPISTI--PGDFPLSAELRKKLEHHLQKRLIQHR-----WGL-PHRI-HESLSLLHPQSPI-------------------LEISES-E--NSEG----PLH------------------SSLVEGQSHNDLKN---FKSRK-PRSFQKRSSNMLSL------ENV--GKFQGYSQENG--------PKDHLLH----EP-ETSSE-EDLSA-NSESNLEGH--------MMHLPGNDS--------GVSLGQ-KQLANALTTHLSK-KFEEISKSQVP-GSVRSSQQPSLHKVLG-SPLEHECSLLFWGPPS-LHSESLVATAW-AGGRSSST--RSHCIKFNEAHT-----------------------------------------------------HI-PGPSLQDSPLV-------LPSVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPAQLL-----CFPQKPQLTCP---SQVR-----ACGTTCSTS-QKKAQSFLPIEN------------------------------------------------QDLQWTL-------QKPLK---WRQALNSKLQKGQEPISLPTLNLPQGSQ-----ASEAPQAVSIL--SG-DSNSAELQEKPECHRSGAFSRDEGSENLPHP-ALRL-LPSQDLMQPLGKL-------------------PEKCQG-R--VQDSYSATQPT-Q----------------TSAPTCGRNKTVQN---TGSQSSGR-AFYRGLVTLKL---E--DRR--NV--QQNASED---------RKDTFR----GV-GCTPW-EVQGD----KGAQSN--------IKGPEKYDAGSH----FSRGPDP-KDLQKDLGVHLSR-KFWQINEGMIP-VCVRRSQQPSLHKVLG-SPLERECSLLFWGLPS-LHSESLVATAW-AGERSSST--RSHCIKFNEAHT-----------------------------------------------------HI-PGPSLQDSPLV-------LPSVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPAQLL-----CFPPKPQPTSP---SQVR-----ACGTTCSTS-QKKAQSFLPIEN------------------------------------------------QDLEWTL-------QKPLK---WRQALNSKLQKAQEPISLPTLNLPQGSQ-----ASEAPQSFSML--SG-DSCSAVLEKKPECHRPGRFNRDEGSENLPHP-AFRF-Q---TPMQPPGKL-------------------PSKCQG-Q--AHDSHGPTQHT-K----------------HSVPACNSSRDVQK---TKSWHCGT-LLNKGSVNLNL---K--ERS--NV--LPEANKG---------QEDTSQ----ST-E------SPLP----KDAESD--------TIWSEEYNSRSH----FSRDPDQ-KILGRGLQAHPSR-KLGQISEGIIP-ACVRQKLSYPKVLG-HHLQQKYNQLFWGLPS-LHSESLVATAW-ISEGSSVP--QSSSFLFNGISS----------------ACPTQMQAKLSPLLSQS----QPPS---------QLEFQ-SQPLVSSVP--QFQPP-SLAQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILTQDHRQ-----SSLPILSPS-P---PQIE-----ACEVSCLIA-QDKSQFLIPPEI------------------------------------------------QHPEWPL------LQKQLE---SGWALSSVIKRSQEVFSVFTSNLPEDSW-----A------VSLL--PENFPISAELRKQLEQHLQKWLIEHR-----WEL-PRKIQ-ESLELRQLQGEL-------------------PGTCQA-K--GKHG-----PS-R----------------PSACAGKSNKDTQK---VEF-----------QLSQGM---G--K------GLGYILGKV--------PK-DLSR----DS-ESSLM-GFQEV-SSGES-EC---------DLGLSMSDSGSD----LLKSLD--KNLENILKDHLGR-KLGKISGSLIP-VSVHKSQKLSDPRLLQ-ESFWKNYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--QSPPFLFNEMSN----------------VCPIQRETTMSPLLFQA----QPLS---------HLEPE-CQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SLIK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQVE---DRLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQHIKKWIIQH------WGN-LGRI-QESLDLMQLQDES-------------------PGTSQA-K--GKPR-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----LEKDP--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGV-TSE-ESERNLR--------KPLRSDSGSD----LLRCTER-THIENILKAHMGR-NLGQTNEGLIP-VRVRQSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGHSS-----MFVFFNGITN----------------TSIS----HESPVLPPP----QPLS---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSQAQPQ-----SPFPALLPSPL---FLSR-----ICGVCFHRP-QNEARSLLPSEI------------------------------------------------NRLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPVLVRK-----SFKVHVPISII--PGDFLLSSEERKKLQQYIRKRIIQCR-----WGL-LRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLN------------------ISLVEGQRCNVLKK---SGSSF-PRSFHERSSNMLSM------ENV--GNYQGYSQETA--------PKDHLLH----DL-KTSSD-EDLRS-NSERDLGTH--------MMRLSGNDS--------GERLGQ-KQLENALTVHLSK-KFEEINEGRIP-GIVHSSNSQVSA------------FS-GSQETTR---TWC-----------DFNSSVQQDHL--SR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QRDTTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SPMK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPPRVQKSQDIFSVSTPNLPQERG------------IPLFWGLPS-LHSESLVANAW-VTDRSCTL--QSPPF-FNQISN----------------VCPIQRETTMTPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFW----PTPMAQAEAQAHLP-----SSFPVPSPTFP---SPIK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQLE---DRLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQH--------------MGQ-PGRI-QESLDLMQLQDES-------------------PGTSQA-K--GKPR-----PW-Q----------------SSMSTGESSKETQK---VK---------------FQ-----LEKDP--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGA-TSE-EN--------------PLRSDSGKE----SYRKH---------------P-EIGPDQRGQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVF-LQRGRSS-----MLVFFNGITN----------------TSIS----HEPPVLPPP----QPLF---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSQAQPQ-----SPFPALLPSPP---FLIR-----VCGVCFHRP-QNEAQSLMPSEI------------------------------------------------NHLEWNV------LQKAQE---SVWGLPSVVQKSREDFCPPAASPALVRK-----SFKIHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLN------------------ISLVEGQRCNVLKK---SGSSF-PRSFHERSSNMLSM------ENV--GNYQGYSQETA--------PKNHLLH----DP-ETSSD-EDLRS-NSERDLGTH--------MMHLSGNDS--------GVRLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVF-LQRGRSS-----MLVFFNGITN----------------TSIS----HEPPVLPPP----QPLF---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSQAQPQ-----SPFPALLPSPP---FLIR-----VCGVCFHRP-QNEAQSLMPSEI------------------------------------------------NHLEWNV------LQKAQE---SVWGLPSVVQKSREDFCPPAASPALVRK-----SFKIHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLN------------------ISLVEGQRCNVLKK---SGSSF-PRSFHERSSNMLSM------ENV--GNYQGYSQETA--------PKNHLLH----DP-ETSSD-EDLRS-NSERDLGTH--------MMHLSGNDS--------GVRLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQKLSYPKILG-DHFQQKYKQLFWGLPS-LHSESLVAAAW-IPQT-STL--PSPFFLFNVISS----------------VYPIEMQDKMSPVLSHT----HPLS---------YLDLR-PPPLILSPP--QFQPP-ALNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHLQSSLP-----ALLPSSL-PYK------R-----DYGTSCSQS-QSKSQY-LPTEI------------------------------------------------QYRERPS------LTKQLE---SRLAFPLMDQRPQEAYDVLAPNLSQD-L-----A------VSIL--PDNFPISFELREKLEQHIQKWLIQHR-----WDL-PRKIQ-ESLEVMQFQNAV-------------------TEACQT-R--DKPG-----PSPR----------------SFVSMGEHSKGGPK---VRF---------------QL---E--KES--GKNLGPILGKV--------SK-DPIR----HL-EKTKLLRMTILG-GDLGQKRSQLFWGLPS-LHSESIVATLLVLPLNSYPL--EPHLVLFNGVCR----------------AVAAPGLGHGSAALPQP----HTL---------PLSFAG-PQPFPR---GA--RPQ-PQTLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FPR----AHVR-----CPPSPMR-SPP---LPRG--------RTFQRP-HTRTVSGVLGGN------------------------------------------------EHLQGYL------LQNHQD---SLWSLVPEWQQYGTPFGLLVPSLPLVSQ-----PSRNYVSTP-R--TGHFHFGSELQDNLEPYGPNNPIPPW-----CYHQASGR-TGVLEVMVPRFKP-------------------TETSPH-S--CKCT-----RP-Q----------------RTVHWDQSCSDLRT---AEPRR-SGSFCERASVKPQL---N--KDV--AQNLGQILGKC--------PFGSPQM----IS-GCYVL-KGLRV-VPET--EIKWA--------CPSGVGLENEQDGISRKSLDQ-RQTRSILRLHVSR-KLWQITMGRIP-IKVCCSQQSPHLRTSE-DQLGLKHIQLFWGLPS-LHSESMNSIAT-VWTDSSL-----ISGCFN--------------------------RFSDSPVLINY----TPLS---------LPESQ-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLPQTLSLSQ----SQTVPPAKPPAQLQ-----YPIPVLSPSPL---TQLR-----ICGVYFHRP-QHKVQPLEPSAV------------------------------------------------HCLNYNI------LKKKLE---RVWGLPTVVKKSQEEFCPPPPKPSLVKQ-----SSKTHVSRFIC--LGNFLLTSELQKKLEHHLRKRLILQR-----WGL-PQRI-YKSLPWMNPLAEL-------------------PEASSS-T--SNYG----LSW------------------ISFFKQQGSKDLHN---IVLNK-PGSFPTRQS--------A-EKLL--KAR-EHSTEAV--------KKYQLWS----NT-KGTLD-NGLQS-NCETVLKHH--------TGSLPGKPLG-----TLQVSQCW-KKLETALQKYLIR-HLGETNECQIS-GTVSRQKLSDPRILQ-ESFQKNYSQLFWGLPS-LHSESLVANAW-VTERSYTL--QSPPFLFNGISN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PIPMAQAEAQAHLQ-----SSFPVLSPAFP---SPIH-----NSGVACPAS-QKKVQALCLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPISPELRRQLEQHIQKWFIQH------QGN-LGRI-QESLDLMQLRDEL-------------------SGTSQA-K--GKPR-----PW-Q----------------SSTSTGESSKEAQK---VK---------------FQ-----LERDP--CPRLGQILGQT---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERDLR--------KPLRSDSGSD----LLRRTER-NRIENVLKAHVGR-KLGQINEGLIP-VSVRRSRPRGR------MKN----------------------------------------------------------HSL----RAC--RACPRG-------LE-ETWDLFS-QLQ---------------------------------------------SLLGP---HPDKG-DF--------------------GQLSGPDPPGEVGKRAPD-G------DSRSS---HEPMEDTA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKTS-NLAPQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGRSS-----MFVFFNGITN----------------TSIF----HKFPVLPSP----QPLS---------LPNTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSQAQHQ-----SPLPVLLPSPP---FLIR-----ICGVCFHRP-QNEAQFLTPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALVRK-----SFKVHVPVSII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------HSSVEGQSLNVLKK---FGSII-PRTLHERSSNMLSL------ENV--GNYQGCSQENG--------PKNHLLQ----DP-ETSSD-EDLRS-NSERDLDTH--------MMHLSGNHS--------GESLGQ-KQLENALTAHLSK-KFEEINEGRMP-GTVHSSQQPPYSTCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGHSS-----MFVFFNGITN----------------TSIS----QESQVFPPP----QPLS---------LPSTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVQSQAQHQ-----SPLPALLPSPL---FRIR-----ICGVCFHRP-QNEAQFLTPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALARK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------RSSVEGQSLNVLKK---FGSST-PRTFHERSSNMLSL------ENV--GNYQGHRQENG--------PKNHLLQ----DP-ETSSD-EDLRS-NSERDLDTY--------MMHLSGNHS--------GESLGQ-KQLENALTAHLSK-KFEEINEGRMP-GTVHSSQQVSDATAVG-DHLQQKCSQLFWNLPS-FNSESLVATAW-VSSKPSSQ--NAHSVSLDEAST----------------SLPGEPEVEASSQLSQA----PPQP---------HHMAQ-PQRFTPAWPQ--SQPP-PLAGIQTQ-AHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-----PPVPSLPCSSP---PQIR-----DCGASYPTT-QEKTESVIPAGK------------------------------------------------ENLEWTL------KKR-PK---WKRVLPSLLQKSPTVLSQPTAHLPQERP-----ASWSPKSAPIL--PG-VATSPELPEHRWQ-GRSAI-HQEQS---CGP-PSGF-RASGDLPPPEGEF-------------------PGRPQS-R--AADTQEALLPS-Q----------------ASGFAGKGRKDVQK---AGFRS-SGR-----------------------FSGKGCLRSK---------LGPDPSRDR-GS-GRTSV-KFLE--EDKEEAEGDMW--------RPWKYQSVNS----APRDPDK-EHLENNLQIHLAR-KVGEIKEGWIP-VPVRRSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VKHGHSS-----MFVIFNGITN----------------TSIF----HKFPVLPPP----QPLS---------LPNTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSHNQHQ-----SLLPALLPSPP---FLIR-----ICGVCFHRP-QNEARSLTPSEI------------------------------------------------NLLECNV------LQKVQE---S-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ST----------------SLPGEPEVEASSQLSQA----PPQP---------HHMAQ-PQPFTPAWPQ--SQPP-LLAGIQTQ-AHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-----PPVPSLPCSSP---PHIR-----DCGASYPTT-QEKTESVIPAGK------------------------------------------------ENLEWTL------KKR-PK---WKRVLPSLLQKSPAVLSQPTAHLPQERP-----ASWSPKSAPIL--PG-VATSPELPEHRWQ-GRSAI-HQEQS---CGP-PSRF-RASGDLPPPEGEF-------------------PGRPQS-R--AEDTQEALLPS-Q----------------ASGFAGKGRKDVQK---TGFRS-SGR-----------------------FSGKGCLRSK---------PGPDPSRDR-GS-GRTSV-KFLE--EDKEEAEGDMW--------RPWKYQSVNS----APRDPDK-KHLENKLQIHLAR-KVGEIKEGWIP-VPVRHSQKLSDPRILQ-ESFQKNYSQLFWGLPS-LHSESLVANAW-VTERSYTL--QSPPFLFNGISN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PIPMAQAEAQAHLQ-----SSFPVLSPAFP---SPIN-----NSGVACPAS-QNKVQAVCLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPISPELRRQLEQHIQKWFIQH------QGN-LGRI-QESLDLMQLRDES-------------------SGTSQA-K--GKPR-----PW-Q----------------SSTSTGENSKEAQK---VK---------------FQ-----LERDP--CPRLGQILGQT---------PQNLSR----GM-ESFPG-KVLGV-TSE-ESERDLR--------KPLRSDSGSD----LLRRTER-NRIENVLKVHVGR-KLGQMNEGLIP-VSVRRSQDPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-GQRGRTS-----MFVFFNGITN----------------TSIF----HKFPVLPPP----QPLS---------LPNTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSQAQHQ-----SPLPVLLPSPP---FLIR-----ICGVCFHRP-QNEAQSLTPSEI------------------------------------------------NLLECNV------LQKVQG---SVWGLPSVVKKSQEDFCPLAPNLALVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLHPQSKI-------------------SELSVS-E--SIHG----PLH------------------RSSVEGQSLNVLKK---FGSSI-PRTFHERSSNMLSL------ENV--GNYQGYRQENG--------PKDHLLH----DP-ETSSD-EDPRS-NSERDLDTH--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQQPPYSKCFE-DHFEQKYVQLFWGLPS-LHSESLHPTVL-VKHGRSS-----MFVFFNGITN----------------TSIS----QESQVLPPP----QPLS---------LPSTR-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVQSQVQHQ-----SPLPALLPGPL---FRIR-----ICGVCFHRP-QNEAHQQVSDATAVG-DHLQQKCSQLFWNLPS-FNSESLVATAW-VSSKPSSQ-NNAHSVSLDKAST----------------SLPGEPEVEASSQLSQA----PPQP---------HHMAQ-PQPFTPAWPQ--SQPP-PLAGIQTQ-AHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-----PPVPSLPCSSP---PQIR-----DCGASHPTT-QEKTESVIPAGK------------------------------------------------ENLEWTL------KKR-PK---WKRVLPSLLQKSPTVLSQPTAHLPQERP-----ASWSPKSAPIL--PG-VATSPELPEHRWQ-GRSAI-HQEQS---CGP-PSGF-RASGDLPPPEGEF-------------------PGRPQS-R--AADTQEALLPS-Q----------------ASGFAGKGRKDVQK---AGFRS-SGR-----------------------FSGKGCLRSK---------LGPDPSRDR-GS-GRTSV-KFLE--EDKEEAEGDMW--------RPWKYQSVNS----APRDPDK-EHLENKLQTHLAR-KVGEIKEGWIP-VPVRRSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGRSS-----MFVFFNGITN----------------TSIF----HKFPVLPSP----QPLS---------LPNTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSQAQHQ-----SPLPVLLPSPP---FLIR-----ICGVCFHRP-QKEAQFLTPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALVRK-----SFKVHVPVSII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------HSSVEGQSLNVLKK---FGSII-PRTLHERSSNMLSL------ENV--GNYQGCSQENG--------PKNHLLQ----DP-ETSSD-EDPRS-NSERDLDTH--------MMHLSGNHS--------GESLGQ-KQLENALTAHLSK-KFEEINEGRMP-GTVHSSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGRSS-----MFVFFNGITN----------------TSIS----QESQVFPPP----QPLS---------LPSTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVQSQAQHQ-----SPLPALLPSPL---FRIR-----ICGVCFHRP-QNEAQFLTPSKI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALARK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------RSSVEGQSLNVLKK---FGSST-PRSFHERSSNMLSL------ENV--GNYQGHRQENG--------PKNHLLH----DP-ETSSD-EDPRS-NSERDLDTY--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQKLSDPRILQ-ESFQKNYSQLFWGLPS-LHSESLVANAW-VTERSYTL--QSPPFLFNGISN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-SQPFISC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PIPMAQAEAQAHLQ-----SSFPVLSPAFP---SPID-----NSGVACPAS-QKKVQALCLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPISPELRRQLEQHIQKWFIQH------QGN-LGRI-QESLDLMQLRDEL-------------------SGTSQA-K--GKPR-----PW-Q----------------SSTSTGESSKEAQK---VK---------------FQ-----LERDP--CPRLGQILGQT---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERDLR--------KPLRSDSGSD----LLRRTER-NRIENVLKAHVGR-KLGQINEGLIP-VSVRRSQKLSDPRILQ-ESFQKNYSQLFWGLPS-LHSESLVANAW-VTERSYTL--QSPPFLFNGISN----------------VCPIQRETTISPLLFQA----QPLS---------HPGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PIPMAQAEAQAHLQ-----SSFPVLSPAFP---SPID-----NSGVACPAS-QIKVQALCLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPPRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPISPELRRQLEQHIQKWFIQH------QGN-LGRI-QESLDLMQLRDES-------------------SGTSQA-K--GKPR-----PW-Q----------------SSTSTGESSKEAQK---VK---------------FQ-----LERDP--CPHLGQILGQT---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERDLR--------KPLRSDSGSD----LLRRTER-NRIENVLKAHVGR-KLGQINEGLIP-VSVRRSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGRSS-----MFVFFNGITN----------------TSIF----HKFPVLPSP----QPLS---------LPNTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSQAQHQ-----SPLPVLLPSPP---FLIR-----ICGVCFHRT-QKEAQSLMPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------RSSVEGQSLNVLKK---FGSII-PRTLHERSSNMLSL------ENV--GNYQGCSQETG--------PKNHLLQ----DP-ETSSD-EDLRS-NSERDLDTH--------MMHLSGNHS--------GESLGQ-KQLENALTAHLSK-KFEEINEGRMP-GTVHSSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGRSS-----MFVFFNGITN----------------TSIS----QESQVFPPP----QPLS---------LPSTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVQSQAQHQ-----SPLPALLPSPL---FRIR-----ICGVCFHRP-QNEAQFLTPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALARK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------RSSVEGQSLNVLKK---FGSST-PRTFHERSSNMLSL------ENV--GNYQGYRQENG--------PKNHLLH----DP-ETSSD-EDLRS-NSERDLDTY--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQVPQSKTSG-DDAESKPSQLFWGPPS-LHSEALHPTTP-AESDRSP-----TPVYFN--------------------SMAEASVA-----ITLP----TAPL---------VTESQ-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TWLQTQSRSH----SQADPRTESQTQPQ--PHTPVLVWTH-SPH---SQLK-----VCGVQFHRT-QGA-QPLGPSET------------------------------------------------QRLEYNI------LKKEQE---KVWGLPSVVKKSQDTFCPPPPKPSLVSR-----SFKSQTPRPIL--LGDFPLTKELRKKLEHHLRKRLIQHR-----WGL-PHRI-NESLSLMYPQSEL-------------------MEPLAS-G--RSCG----LSW------------------ISLFKYRGSMESYA---TVLSG-SGKSRNSTSESHPL---A-RTEV--KAQ-TYSQDTG--------QEDHLQN----N-FWEAPR-NSLAS-ALKTDQEHL--------AGSRSDQLSS-----LSLVSQCQ-KRIEKALEEHFHK-KAQEIRKGQMP-STVEKSQKLSYPTILG-DNFQEKYNQLFWGLPS-LHSESLVATAW-IPQASSTL--PSPFFLFNVIST----------------AYPVQMRDQMSPVHSCT----RPLS---------YLDLQ-SPPLILSPP--QFQAP-APNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SP----LP-----AQLPSSL-PYT---SDYG-----DYGPSCSQS-QSQSQC-LPTEI------------------------------------------------QHTEGHS------LT-KLE---SRLPLSLMVQRPQEVYDVLAPNLSQD-W-----A------VSIL--PDNFPISCELREKLEQHIQKWLIQHR-----WDL-PRKIQ-ESLEVMQLQNTV-------------------TEPCQT-R--DKPG-----PS-R----------------SSVSMGNHSKDDHK---VRF---------------QI---K--KES--GKNLGPILGNI--------SK-DPNR----YL-EKAPV-TLQGT-------------------------------------------QHLSYSKTSE-DQLEDKNTQSFWGLPS-LHSESMNSIAT-VLTDSSL-----ISGCFN--------------------------RFSDSPMLTHR----TTLP---------LSESQ-LH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLSQSLSQSQ----SQPVSQANLQAQLQ-----LPNPVLSP-H----SQLR-----ICGVYFHSP-QNEAQPLEPTAI------------------------------------------------HCLEYNI------LKKEQE---RVWGLPTVVINSQQEFCPPPPNPSLVSQ-----LSKTHVPKSIS--IEKCFITSELQKKFEHHLRKRLILQR-----WGL-PKRI-RESLLWINPQAEL-------------------PESPSA-K--SNYG----LSW------------------IPFFKQQSKKDLHK---TILSQ-PGSFPAKQL--------E-EKLL--KLCSKQGLEMV--------QKQQTWS----NT-KGTLD-NGLQS-DCETNLQCH--------SDSLSCKPLG-----TSEVSQCQ-KKLETSLKEHLTT-RLNETIERQIT-STMSGSQKLSYPKISE-DHFQQKCDQLFWGLPS-LHSESLVAAAW-IPQTTSTL--PSPFFLFNVISS----------------VYPIQLQDKMSPMLPHT----HPLS---------YLDLQ-SPHLILSPL--EFQTP-ALN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LP-----VLLPSSL-PYN------S-----DFGTSYSQS-QSKPQY-LPTEI------------------------------------------------KYNKKPS------LAKQIE---NRSTLPLMVQKPQEAYDILAPNPSQD-W-----V------VSIL--PDNFPICRELREKLEQHIQKWLIQHQ-----WNF-PHKIQ-VSEKMKELQNTV-------------------IGNCQT-R--DKPG-----TL-Q----------------A---LGEHSNEGQK---RKF---------------QL---E--KES--GKNLGPILGKI--------SK-DPIR----GL-EKQGLAQVQSSG-GQLEAMPMQHFWGLPY-LHSESMSCITT-LSSHCSS-----MCIWFN--------------------------RTTDSPALAPP----SPLP---------LPERQ-SQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLTQSQ----YQSIQLATPHSQLQ-----T-LPGPSPSSQ---SQVR-----VCGVYFRRS-Q-EAKALLQSEI------------------------------------------------HHLEYNM------MAKDPE---REWALPSVVQKPQEELSLLPSKLSLAIK-----SSKLQTPRSVP--PRDFPLADGFQKMFEQHLRKRLILQR-----WGL-PQGI-YKSQLWANPDPS-----------------------EAS-K--SSSG----LSG---------------------FKHKDNKAWPN---TVSNQ-SGSPQEK---SVSV---E-RKTV--KAH-EQTLEII--------QK-YICS----NS-KTALD-NSLPS-DHE-NLQGH--------SGSLSDQSSE-----TSQVSQCR-KKFETPPKEHLKS-HIDGTNEDQVP-VTLSQPLPHSKTFE-DHEELQSSLLFWGPPS-LHSEALSPTTT-NAYDRSS-----ALVCFN--------------------SMAEASIADYSHGCMLP----TPLH---------AY--Q-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TWLQTEPQSH----PQRDPPAELQPQP--QPQSRVSILTF-SHQ---SEPR-----DCGVHFHRP-QGDEQLLSSSEM------------------------------------------------QCLEYNI------LKKEQE---RVWGLPLMVKKSKYTFCPSPPKVLLGSR-----SSKACTPRPIL--PGDFPLTSELQKKLEHHLRKRLIQHR-----WGL-PDRI-DKSLSLMSPQSEL-------------------IDFSES-K--KNRG----LSW------------------ITFFKYQGNKDSQV---LSGGS----SRNRMPRRHSL---R-ETRV--KER-TYSQDRG--------HNDQSWG----NNFQEASQ-NSVQS-HLKTHRKSR--------MGRQPPRFSS-----PSQVKQYQ-RGIEKALEKHLNK-KIREISRGEIP-TTVDRSQVLYVKIPE-GDLGQKHSQLFWGLPS-LHSESIMATLL-VPASSYSP--EPCLVLFNGVCK----------------TASAPVLSHGLPALPQP-----------------LTLVH-PQPLPKVA--P--QPQ-TLTEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQ----VHMQ-----SPLSSMA-LPS---LPCG--------SALQIP-QTRTVSDVLNGK------------------------------------------------GHLQYHL------VQNPQD---SLWGLVPECQQYETALGLPVHSFPVGSQ-----SSQTYVSVP-G--SGLFHFSSEHQNNLDPYGPNNLTSPS-----CFEL-CNR-PGVPEVMNTQFNP-------------------TGVSSY-C--YKYA-----TS-Q----------------CCVHWGNICADPGN---GELSH-SESYCVKVPMKPQL---R--KDA--AKNLGQILGKC--------PLDNTQM----IS-GCCIL-NGLKT-IPET--EGESV--------CHSRTSLENEQLTISKKNLDQ-RHMRSILRLHMSR-KCWQITMGRIP-IVVCCSQQPSHLKNSE-DQSEIKDIQLFWGLPS-LHSESLKHEAA-NTGNSYP-----GRDYFN--------------------KVAQASTGSHSSNLTYS----TPLP---------LPESD-QQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQI--VPQSQ----IMPDSLANSKAQPQ-----SLAQLLSPSPQ---SQLG-----ICGVRFHSL-KNEAQPLTPCEI------------------------------------------------QQLEYNL------LQKALQ---SFLGLPTLTETFQESFCPPPPKISSTRN-----SSKVHAPKTIL--PGDFPLSHTLKRKLEHHLRKRLIQRH-----WGL-PHRI-LESLSFLSPHSEI-------------------PEAPKP-R--DTHG----LSR------------------VSLYKFNANTNLPS---SGVSQ-SERSCKKPLESHPP---Q-EKDI--NVQ-RHRPGIN--------QRDPIQC----KS-CGATK-STVHS-NSETDPELQ--------LGNMSGNISK-----ASWVRQCQ-KECEAYLQKHLGK-DTKEISGSERP-SAVDSSQQPPHSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQHGRSS-----MFVFFNGITN----------------TSIS----HESPVLPPP----QPLS---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVKSQAQHQ-----SPFQALLPSPL---FLIR-----VCGVCFHRP-QNEAQSLMPSEI------------------------------------------------NNLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPVLVRK-----SFKVHVPISIL--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELFVS-E--SNHG----PLN------------------ISSVEGQRHNVLKK---FGSST-PRNFHERSSNMLSL------ENV--GNYQRYSQEIA--------PKDHLLH----DP-ETSSD-EDLRS-NSERDLETH--------MMHLSGNHS--------GDSLGQ-KQLENALTVHLSK-KFEEISENRVP-GTVRSSQKLSDPRLLQ-ESFRKHYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--QSPPFLFNEMSN----------------VCPVQRDTTLSPLLFQA----QPLS---------HLGPK-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---PLIK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDIRSVSTPNLPQESL------------TSIL--PENFPVSPELQRQPEQHIKKWIIQH------WGN-LGRI-QESPDLMQLGDES-------------------PGTSQA-K--GKPR-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----LEKDP--CPHLGQILGQT---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERILR--------KPLRSDSGSD----LLRCTER-NRIENLLKAHIGR-RLSQTNEGLVP-MTVHRSQKLSDPRLLQ-EGFRKHYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--QSPPFLFNEMSS----------------VSPVQRDTTLSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---PLIK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDICSVPTPNLPQESL------------TSIL--PENFPVSPELQRQLEQHIKKWIIRH------WGN-LGRI-QESPDLMQLGDES-------------------PGTSQA-K--GKPR-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----QKKDP--CPHLGQILGQT---------PQNLSR----GM-ESFPG-KVLQA-TSE-ESERILR--------KPLRSDSGSD----LLRCTER-NRIENLLKAHIGR-RLSQTNEGLVP-LTVRRSVQQDHL--SR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QRETTMSPLRFL------------------------SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFQ----PTPMAQA----DLQ-----SSFPVLSPAFP---SPIK-----NTEVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSSIQKSQDVFS--------ERL------------TSIL--PENFPVSPELRRQLEQH--------------MGQ-PGKI-QESLDLMQLRDES-------------------PGTSQA-K--GKPR-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----LERDR--CPHLGQILGQT---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERILR--------KPLRSDSGSD----LLRCTER-NRIENLLKAHIGR-RLSQTNEGLVP-LTVRRSQKPPYSKCSE-DHLEQKYVQLFWGLPS-LHSESLYPTVL-VQPGHPS-----VFVFFHGITN----------------TSIS----HESPVLPPP----QPLF---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQSEAQHQ-----SPFQALLPSPL---FLIR-----GCGVCFHRS-QNEAQSLMPSEI------------------------------------------------NHLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPVLVRK-----SFKVHVPISIL--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSK-------------------------------------------------------------NFRGQRHNVLKK---SGSSI-PRSFHKRSSNMLSL------ENV--GNYQGYSQENA--------PKNHLLH----DL-ETSSD-EDLRS-NSERDLETH--------MMHLSGNHS--------GESLGK-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSNHL--SC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QREITMSPLLFLD----QPLS---------HVGPE-PQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPTAQAEAQAHLQ-----SSFPVLSPAFP---SPIK-----NTGVACPAS-RNKVQALSLPET------------------------------------------------QHPERPL------LRKQLE---GGLALPSSVQKSQDIFSVSTPNLPQERL------------TSIL--PENFPVSPELRRQPEQH--------------MGQ-RGRI-QESLDLMQLRDEP-------------------PGTSQA-K--GKPR-----PW-Q----------------SSTSTGERSKEEQK---VK---------------LQ-----LERDP--CPHLGQILGET---------PQNLSR----GM-ESFPG-KVLGV-TSE-ESQRNLR--------KPLRSDSGSD----LLRHTER-HHIQHLLKAHMRR-KLSQTNEGLIP-VRVRRSQQVSDATTVG-NHLQQKRSQLFWDLPS-LNSESLATTVW-VSRNPSSQ--NAHSVPLDKAST----------------SLPGEPEVEASSQLSQA----PPQP---------HHMAQ-PQHFTPAWPQ--SQPP-PLAEIQTQ-AHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-----PPVPSLGCSSP---PQIR-----GCGASYPTS-QERTQSVIPTGK------------------------------------------------EYLEWPL------KKR-PK---WKRVLPSLLKKSQAVLSQPTAHLPQERP-----ASWSPKSAPIL--PG-VVTSPELPEHWWQ-GRNAI-HQEQS---CGP-PSRL-QASGDLLQPDGEF-------------------PGRPQS-Q--AEDTQQALLPS-Q----------------PSDFAGKGRKDVQK---TGFRS-SGR-----------------------FSDKGCLGSK---------LGPDPSRDQ-GS-GRTSV-KALD--EDK-EAEGDLR--------RSWKYQSVSS----TPRDPDK-EHLENKLQIHLAR-KVGEIKEGWIP-MPVRRSQKCSDPRLLQ-ESFWKNYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--QSPPFLFNEMSN----------------VCPIQRETTMSPLLFQA----QPLS---------H-----RQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFL----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SLIK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQLE---GRLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQHIKKWIIQH------WGN-LGRI-QESLDLMQLRDES-------------------PGTSQA-K--GKPS-----PW-Q----------------SSTSTGESSKEAQK---VK---------------FQ-----LERDL--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGV-TSE-ESERNLR--------KPLRSDSGSD----LLRCTER-THIENILKAHMGR-NLGQTNEGLIP-VRVRRSQQPPHSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGHSS-----MFVFFNGITN----------------TSIS----HESPVLPPP----QPLS---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVKSLAQPQ-----SPFRALLPSPL---FLIR-----ICGVCFHRP-QNEARSLLPSEI------------------------------------------------NHLEWNV------LQKVQE---SLWGLPSVVQKSQEDFCPPAPNPELVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRRRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--RIHG----PLN------------------ISLVEGQRCNVLKK---SASSF-PRSFHERSSNMLSM------ENV--GNYQGYSQETV--------PKDHLLH----GP-ETSSD-KDLRS-NSERDLETH--------MMHLSGNDS--------GVRLGQ-KQLENALTVRLSK-KFEEINEGRMP-GTVHSSQKLSDPRLWQ-ESFWKNYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--QSPPFLFNEMSN----------------VCPIQRETTMSPLLFQA----QPPS---------HLGPE-CQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SLIK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRRQLE---GRLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQHIKKWIIQH------WGN-LGRI-QESLDLMQLRDES-------------------PGTSQA-K--GKPS-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----LERDP--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGV-TSE-ESERNLR--------KPLRSDSGSD----LLRCTER-THIENILKAHMGR-NLGQTNEGLIP-VRVRRSQKLSDPRLWQ-ESFWKNYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--QSPPFLFNEMSN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-CQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SLIQ-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRRQLE---GRLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQHIKKWIIQH------WGN-LGRI-QESLDLMQLRDES-------------------PGTSQA-K--GKPS-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----LERDP--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGV-TSE-ELERNLR--------KPLRSDSGSD----LLRCTER-THIENILKAHMGR-NLGQTNEGLIP-VCVRRSQKLSDPRLWQ-ESFWKNYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--QSPPFLFNEMSN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-CQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SLIQ-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRRQLE---GRLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQHIKKWIIQH------WGN-LGRI-QESLDLMQLQDES-------------------PGTSQA-K--GKPS-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----LERDP--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGV-TSE-ELERNLR--------KPLRSDSGSD----LLRCTER-THIENILKAHMGR-NLGQTNEGLIP-VRVRRSQKLSDPRLWQ-ESFWKNYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--QSPPFLFNEMSN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-CQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SLIQ-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRRQLE---GRLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQHIKKWIIQH------WGN-LGRI-QESLDLMQLRDES-------------------PGTSQA-K--GKPS-----PW-Q----------------SSMSTGEGSKEAQK---VK---------------FQ-----LERDP--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGV-TSE-ELERNLR--------KPLRSDSGSD----LLRCTER-THIENILKAHMGR-NLGQTNEGLIP-VCVRRSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVF-VQHGRSS-----MFVFFNGITN----------------TSMS----HESPVLPPP----QPLF---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SLHLTQVKSLAQPQ-----SPFPALPPSPL---FLIR-----VCGVCFHRP-QNEARSLMPSEI------------------------------------------------NHLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPVLVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQNKI-------------------SELSVS-E--SIHG----PLN------------------ISLVEGQRCNVLKK---SASSF-PRSFHERSSNMLSM------ENV--GNYQGCSQETA--------PKNHLLH----DP-ETSSE-EDLRS-NSERDLGTH--------MMHLSGNDS--------GVRLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVF-VQHGRSS-----MFVFFNGITN----------------TSMS----HESPVLPPP----QPLF---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SLHLTQVKSLAQPQ-----SPFPALPPSPL---FLIR-----VCGVCFHRP-QNEARSLMPSEI------------------------------------------------NHLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPVLVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQNKI-------------------SELSVS-E--SIHG----PLN------------------ISLVEGQRCNVLKK---SASSF-PRSFHERSSNMLSM------ENV--GNYQGCSQETA--------PKNHLLH----DP-ETSSD-EDLRS-NSERDLGTH--------MMHLSGNDS--------GVRLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQKLSDPRILQ-ERFQKNYSQLFWGLPS-LHSESLVANAW-VTERSYTL--QSPPFLFNGISN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PIPMAQAEAQAHLQ-----SSFPVLSPAFP---SPIH-----NSGVACPAS-QIKVQALCLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPISPELRRQLEQHIQKWFIQH------RGN-LGRI-QESLDLMQLRDES-------------------SGTSQA-K--GKPR-----PW-Q----------------SSTSTGESSKEAQK---VK---------------FQ-----LERDP--CPRLGQILGQT---------PQNLSR----GM-ESFPG-KVLGM-TSE-ESERDLR--------KPLRSDSGSD----LLRRTER-NRIENVLKAHVGR-KLGQINEGLIP-VSVRRSQQPPYSKCFE-DHFEQKYVQLFWGLPS-LHSESLHPTVL-VKHGRSS-----MFVFFNGITN----------------TSIS----QESQVLPPP----QPLS---------LPSTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPQGQ----SPHLTQVQSQAQHQ-----SPLPALLPGPL---FRIR-----ICGVCFHRP-QKEAQFLTPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALARK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--NYHG----PLH------------------SSSVESQSLSVLKK---FGSST-PRTFHERSSNMLSL------ENV--GNYQGYRQENG--------PKNHLLH----DP-ETSSD-EDPRS-NSERDLDTH--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHRSQKLSDPRILQ-ESFQKNYSQLFWGLPS-LHSESLVANAW-VTERSYTL--QSPPFLFNGISN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PIPMAQAEAQAHLQ-----SSFPVLSPAFP---SPIH-----NSGVACPAS-QIKVQALCLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPISPELRRQLEQHIQKWFIQH------RGN-LGRI-QESLDLMQLRDES-------------------SGTSQA-K--GKPR-----PW-Q----------------SSTSTGESSKEAQK---VK---------------FQ-----LERDP--CPRLGQILGQT---------PQNLSR----GM-ESFPG-KVLGM-TSE-ESERDLR--------KPLRSDSGSD----LLRRTER-NRIENILKAHVGR-KLGQMNEGLIP-VSVRRSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGRSS-----MFVFFNGITN----------------TSIF----HKFPVLPSP----QPLS---------LPNTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVQFQAQHQ-----SPLPVLLPSPP---FLIR-----ICGVCLHRP-QKEAQSLTPSEI------------------------------------------------NLLECNV------LQKVQE---SVWGLPSVVKKSQEDFCPPAPNLALVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SIHG----PLH------------------RSSVEGQSLNVLKK---FGSII-PRTLHERSSNMLSL------ENV--GNYQGCSQETG--------PKNHLLQ----DP-ETSSD-EDMKS-NAERDLDTY--------MMHLSGNHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQQSPHLRTSE-DQLEPQHIQFFWSLPS-PHSKSMNSIAT-VWADSSL-----TSECFN--------------------------RFSDSPVLTNH----TPLS---------LPESQ-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLPQTLSPSQ----SQPVPPAKPQAQLQ-----HSVPVLSPSHL---SQLR-----ICGVYFHRP-QDKVQPLDPSAI------------------------------------------------HCLEYNI------LKKEQE---RVWGLPTVVKKSQEEFCPPPPKSSLVKQ-----SSKIHVPRSIS--LGNFLLTSELRKKLEHHLRKRLILQR-----WGL-PKRV-HKSLSWMSPRAEL-------------------PESSSS-T--SNYG----LSW------------------ISFFKQQDSKNLHN---IVLNE-PGSFPARQS--------R-EKLL--KAR-RNSLETV--------QKHQLWS----NT-KGALA-NGLQS-DCETNLQCH--------PGSLSGKPSG-----TSEVSQCQ-KKLETALQKHLIS-HLNETNEGHIS-GTVSQKLSYPKILG-DHFQQKYNQLFWGLPS-LHSESLVAAAW-IPQT-STL--PSPFFLFNAISS----------------GYPVQMQARMSSVLSHT----HPLS---------YLDLQ-SPPLILSPP--KFQPP-TLNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTLQSPLP-----ALLPSSLSSYT------R-----DYGTSCSQS-QRKLQC-LPTEI------------------------------------------------QYRERPS------VTKQLE---SRLALPLMVQRPQEVYDVLTSNISQD-L-----A------VSIL--PDNFPISCELREKLEQHIQKWLIQHR-----WDL-PRKIQ-ESLEVMQLQSTV-------------------IE-SQP-R--DRPG-----PS-R----------------PFVSMGEHSMDGQK---VRF---------------KL---E--RES--GKNLGPILGKI--------SK-HPIK----HL-EKSPV-K-----------------------------------------------NLQQVPHLKTSE-DHAEPKPPQRFWGPPS-LHSEALQPPTT-ASPDRSS-----TFVGFN--------------------SMAEASGADSSPAVTLP----TPLF---------VTKSQ-SQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TWLQPLSQSH----SQHDPPAESQAQPQ--PNPLTSVLTF-SPQ---TQVR-----VCGVRFHRP-QKEGQPLGPSEK------------------------------------------------QYLEYNI------LKKRQE---RVWGLPSVVQKSQDAFCPPPPKRLLASQ-----SFKSYSPRPIL--PGDFPLTNELRKKLEHHLRKRLIQHR-----WGL-PHRI-NESVSLTCPQSQF-------------------VDFSES-R--KSHG----LSW------------------ISLYKHRGSRESHT---IVLSG-SGSFHNGTSEYHLL---E-ETEV--KAQ-TYSQDAG--------KKDHLQS----N-FQEAPA-NSLQS-DLKTDQERH--------AGGQSGQLSN-----PSRVNQCQ-KRIENALAEHLSR-KTKEIRESQIP-SSVVRSQGLAQAQTTE-DQSEPKFTQHFWGLPY-LHSESMNAIST-LSTHCSS-----TYIWFN--------------------------GTPDSSVLNLS----TPLS---------LPENP-SQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAQSQ----SQGVLLAMSQNQFQ-----PPIPETSSSSQ---SQLR-----ICGVYFHRS-QDKTKTLLQAQI------------------------------------------------HHLECSI------MTKVQE---RVWGLPSVVQKSQEDSCLLPAKPSLVRQ-----SSETHAPRSIP--PGDFPLTDAFRKKLERHLQKRFILQR-----WGL-SQRI-FKSQPWVNPDLS-----------------------ESS-Q--CSYG----LSW------------------ASFFQHQESKD-PH--DTVSNQ-PGSSQERYSESLSL---E-GKMV--KAQ-GQSPEIA--------QR-CLWS----NS-RGALG-NGLQS-DCKTNLRSH--------PGSLSG---------ISQVRQCQ-KKLETAL-----------------------------------------------------------------------------------NSQVSA------------FS-GSQETTK---TWC-----------VFNSSVQQDHL--SR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QRDTTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTSMAQAEAQAHLQ-----SSFPVLSPAFP---SPMK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPERPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQERL------------TSIL--PENFPVSPELWRQLEQH--------------MGQ-RGRI-QESLDLMQLQDEL-------------------PGTSQA-K--GKPR-----PW-Q----------------SSTSTGESSKEAET---VK---------------FQ-----LERDP--CPHLGQILGET---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERNLR--------KPLRSDSGSD----LLRRTER-NHIENILKAHLSR-KLGQTNEGLIP-VSVRRSQQVSDATTVG-NHLQQKRSQLFWDLPS-LNSESLAATIW-VSRNPSSQ--NAHSVPLDKAST----------------SLPGEPEVEASSQLSQA----PPQP---------HHMAQ-PQHFTPAWPQ--SQPP-PLAEIQTQ-AHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-----PPVPSLGCSSP---TQIR-----GCGASYPTS-QERTQSVIPTGK------------------------------------------------EYLEWPL------KKR-PK---WKRVLPSLLKKSQAVLSQPTAHLPQERP-----ASWSPKSAPIL--PG-VVTSPELPEHWWQ-GRNAI-HQEQS---CGP-PSRL-QASGDLLQPDGEF-------------------PGRPQS-Q--AEDTQQALLPS-Q----------------PSEFAGKGRKDVQK---TGFRS-SGR-----------------------FSEKGCLGSK---------LGPDPSRDQ-GS-GRTSV-KALD--EDK-EAEGDLR--------RSWKYQSVSS----TPRDPDK-EHLENKLQIRLAR-KVGEIKEGWIP-MPVRRSQKLSDPRLLQ-QSFWKNYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--RSPPFLFNEMSY----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-CQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SLIK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQLE---GRLALPSEVQKSQDVFSVSTPNLPQESL------------TPIL--PENFPVSPEIWRQLELHIKKWIIQH------WGK-LGRI-QESPDLMQLRDES-------------------PGTSQA-K--GKPS-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----LESDP--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGV-TSE-ESERNLR--------KPLRSDSGSD----LLRCTER-THIENILKAHMGR-HLGQTNEGLIP-VRVRRSQQAPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGHSS-----MFVFFNGITN----------------TSIS----HEPPVLPPP----QPLF---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SLHLTQVQSQAQPQ-----CPFPALLPSPL---FLIR-----VCGVCFHRP-QNEARSLLPSEI------------------------------------------------NHLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPALVRK-----SFKVHVPISII--PRDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SNHG----PLN------------------ISLVEGQRCNVLKK---SASSF-PRSFHERSSNMLSM------ENV--RNYQGYSQETA--------AKDHLLH----DP-ETSSD-ENLRS-NSERDLETH--------MMHLSGNDS--------GVRLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQKFSDPRLLQ-ESFQKNYSQLFWGLPS-LYRESLVANAW-VTDWSCTL--QSPPF-FNQISN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFW----PTPMAQAEAQAHLQ-----SSFPVPSPTFP---SPIK-----NTGVACPAS-QNKVQALSLSET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQH--------------TGQ-PGRI-QESLDLMQLQDES-------------------PGTSQA-K--GKPR-----PW-Q----------------SSMSTGESSKETQK---VK---------------LQ-----LERDP--CPHLGQILGET---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERNLR--------KPLRSDSGSD----LLRCTER-NHIENILKAHMGR-KLGQINEGLIQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGHSS-----MFVFFNGITN----------------TSIS----YESPVLPPP----QPLS---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SPHLTQVKSQAQPQ-----SPFPVRLPSPL---FLIR-----ICGVCFHRP-QNEARSLLPSEI------------------------------------------------NHLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPELVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WDL-LRRI-HESLSLLRPQSKI-------------------SGLSVS-E--SIHG----PLN------------------ISLVEGQRCNS-------ASSF-PGSFHERSSNMLSM------ENV--GNYQGYSQETA--------PKDHLLH----DP-ETSSD-ENLRS-NSERDLETH--------MMHLSGNDS--------GVRLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQQVSDATTVG-NHLQQKRSQLFWDLPS-LNSESLAATIW-VSRNPSSQ--NAHSVPLDKAST----------------SLPGEPEVEASSQLSQA----PPQP---------HHMAQ-PQHFTPAWPQ--SQPP-PLAEIQTQ-AHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-----PPVPSLGCSSP---TQIR-----GCGASYPTS-QERTQSVIPTGK------------------------------------------------EYLEWPL------KKR-PK---WKRVLPSLLKKSQAVLSQPTAHLPQERP-----ASWSPKSAPIL--PG-VVTSPELPEHWWQ-GRNAI-HQEQS---CGP-PSRL-QASGDLLQPDGEF-------------------PGRPQS-Q--AEDTQQALLPS-Q----------------PSEFAGKGRKDVQK---TGFRS-SGR-----------------------FSEKGCLGSK---------LGPDPSRDQ-GS-GRTSV-KALD--EDK-EAEGDLR--------RSWKYQSVSS----TPRDPDK-EHLESKLQIRLAR-KVGEIKEGWIP-MPVRRSQQPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGHSS-----MFVFFNGITN----------------TSIS----RESPVLPPP----QPLS---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRDQ----SPHLTQVKSQAQHQ-----SPFPARLPSPL---FLIR-----ICGVCFHRP-QNEARSLLPSEI------------------------------------------------NHLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPELVRK-----SFKVHVPISII--PGDFPLSSEVRKKLEQHIRKRLIQCR-----WGL-LRRI-HESLSLLRPQNKI-------------------SELSVS-E--SIHG----PLN------------------ISLVEGQRCNVLKK---SASSF-PRSFHERSSNMLSM------ENV--GNYQGYSQETA--------PKDHLLH----DP-ETSSD-KDLRS-NSERDLETH--------MMHLSGNDS--------GVRLGQ-KQLENALTVHLSE-KFKEINEGRMP-GTVHSSQQAPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGHSS-----MFVFFNGITN----------------TSIS----HEPPVLPPP----QPLF---------LPSTQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPRGQ----SLHLTQVQSQAQPQ-----CPFPALLPSPL---FLIR-----VCGVCFHRP-QNEARSLLPSEI------------------------------------------------NHLEWNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNPALVRK-----SFKVHVPISII--PRDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------SELSVS-E--SNHG----PLN------------------ISLVEGQRCNVLKK---SASSF-PRSFHERSSNMLSM------ENV--RNYQGYSQETA--------PKDHLLH----DP-ETSSD-ENLRS-NSERDLETH--------MMHLSGNDS--------GVRLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQKLSDPRLLQ-ESFWKNYSQLFWGLPS-LHSESLVANAW-VTDRSYTL--RSPPFLFNEMSY----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-CQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPRFR----PTPMAQAEAQAHLQ-----SSFPVLSPAFP---SLIK-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPEWPL------LRKQLE---GRLALPSGVQKSQDVFSVSTPNLPQESL------------TPIL--PENFPVSPEIWRQLEQHIKKWIIQH------WGK-LGRI-QESPDLMQLRDES-------------------PGTSQA-K--GKPS-----PW-Q----------------SSMSTGESSKEAQK---VK---------------FQ-----LESDP--CPHLGQILGET---------PQNLSR----DM-KSFPR-KVLGV-TSE-ESERNLR--------KPLRSDSGSD----LLRCTER-THIENILKAHMGR-HLGQTNEGLIP-VRVRRSQKFSDPRLLQ-ESFQKNYSQLFWGLPS-LYRESLVANAW-VTDWSCTL--QSPPF-FNQISN----------------VCPIQRETTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFW----PTPMAQAEAQAHLQ-----SSFPVPSPTFP---SPIK-----NTGVACPAS-QNKVQALSLSET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQESL------------TSIL--PENFPVSPELRRQLEQH--------------TGQ-PGRI-QESLDLMQLQDES-------------------PGTSQA-K--GKPR-----PW-Q----------------SSMSTGESSKETQK---VK---------------LQ-----LERDP--CPHLGQILGET---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERNLR--------KPLRSDSGSD----LLRCTER-NHIENILKAHMGR-KLGQINEGLI-NSQVSA------------FS-GSQETTK---TWC-----------VFNSSVQQDHL--SR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QRDTTMSPLLFQA----QPLS---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFR----PTPMAQAEAQAHLQ-----SSFPVLSPALP---SPMR-----NTGVACPAS-QNKVQALSLPET------------------------------------------------QHPERPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQERL------------TSIL--PENFPVSPELWRQLEQH--------------MGQ-RGRI-QEPLDLMQLQDEL-------------------PGTSQA-K--GKPR-----PW-Q----------------SSTSTGESSKEAET---VK---------------FQ-----LERDP--CPHLGQILGET---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERNLR--------KPLRSDSGSD----LLRRTER-NHIENILKAHLSR-KLGQTNEGLIP-VSVRRSQEPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPPVL-VQRGCSS-----MFVFFNGITN----------------TSLF----QESPVLPPP----QA------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLPQTLPQGQ----SPHLTQVQSQSQHQ-----SPLPALLPSPP---FLIK-----ICGVCFHRP-QNEARSLTPSEI------------------------------------------------NHLECNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNLTLVRK-----SFKVHVPIAII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------LELSMS-E--SIQG----PLH------------------SSSVEGQSLNVLKK---FGSST-PRTFHERSSNMLSL------ENV--GNYQGYRQENG--------PKNHLLH----DP-ETSSD-ENPRS-NSERDLNTH--------MMHLSGNHS--------GESLGQ-KQLEDALTVHLSK-KFEEINEGRMP-GTVHSSQKLSYPKISG-DHLQEKYDQLYWGLPS-LHSESLVAAAW-IPQTTSTL--PSPFFLFNVISS----------------VYPIHLQDKMSPVLPHT----HPLS---------YLDLQ-PPPLILSPL--EFQSP-ALNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHFQSPLP-----VLLPSSL-PYS------R-----DSGACYSQS-QSKPHC-PTTEI------------------------------------------------QYRERPL------VTKQLE---SRLTLPLMVQK--DAYSILASNPSHD-W-----A------VPIF--PDNFPISCELRDKLEQHIQKWFIQHQ-----WYF-PPEIQ-ESEEVMGLQNSV-------------------TGNYQI-R--DQPC-----TS-Q----------------AHMSTGEHNKQGQK---VKF---------------QL---E--NES--CKNLGPILGKG--------PK-DPVK----GL-EKNVV-KVQGA-NILEP---------ERNLVKHFKSDSRND----SSNYI-D-EDLENNWKANFGT-KSGQINQGLTP-LSMRQSQGLAQVQTAE-GQLEATPSQHFWGLPY-LHSESMSCITT-VSSHCSS-----MCIWFN--------------------------RATDSPALAPP----APLS---------LPDRH-TQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLTQTQ----SGSIHLATAQSQLQ-----P-MPMLSPSSQ---SQVR-----VCGMYFRSS-Q-EMKTLLQPEI------------------------------------------------PYLEYNM------MAREQE---RAWALPSVVQKSQEKVCLLPAKPSLAIQ-----AFKIQTPRSVP--PRDFPLTDGFQKKFEQHLRKRFILQR-----WGL-PQGI-YKSQLWVNPDPP-----------------------ESS-W--SSHG----RSG---------------------LKHEDHKEPPK--PPVLNQ-AGSPQERCSGSVST---E-RKPV--KVQ-EQTVEII--------QK-YLCS----NS-KSALD-NGLPSSDQEMNLQGR--------SSSLSDKPSE-----TSQVSQFR-KKFEAAPQEHLRG-HIDGTNEDQVP-VTVQKLPYSKTSE-DQLEDKHTQFFCGLPS-LHSESMKSIAT-VLTDSSL-----TSGCCN--------------------------RLLDSPVLTHH----TTLP---------LPKSQ-LT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NFSQSLSQSQ----YQPIPQANPQAQLQ-----SPIPVLSP-SL---SQHK-----ICGVYFHSP-QDEAQPLDPSAI------------------------------------------------HCLEYNI------LKKEQE---RVWGLPTVVKNSQQEFCPPPPKPSLVTQ-----PSKIHVPRSIS--LENCLITIELRKKFEHHLRKRLILQC-----WGL-PKRI-RESLSWMNPQGEL-------------------PELCPS-K--SNYG----LSW------------------ISFFKQHGRKDLHNIVDTILNQ-PGSFPAKQL--------E-KKLL--KAK-GHSLETV--------QKQQTWS----NT-KGTLD-NGLQF-DCEINLQCP--------SDSPSCKPSG-----TSEVSRCQ-KKLETSLKEHLTI-HLNETNEGQIT-STMFRSQQLPHSRTSE-DHEELKPAQLFWGPPS-LHSEALRPTT--SLYDRSS-----TFVCFN--------------------SIAEASIADYSHAILLP----TPLS---------VY--G-SQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TWLQPEPQSH----PTCDPLAESQPQPQLQY--PVSVLTLAPSQ---SELR-----YCGVHFHRP-QGDEQALGPSAT------------------------------------------------QCLEYNI------LKKEQE---RVWGLPLVIKKSQNAFCPSPPKFLSASR-----SSKACTPRPIL--PGDFPLTGELQKKLEHHLRKRLIQRR-----WGL-PHRI-DESLSLMCPQPEQ-------------------TDISES-R--RSRG----LSK------------------TPFSKSHGNKDSKA---IGPGG-AGGFLSRMPEGHSL---QQEILV--KEQ-TYSQDTG--------QNDRPQG----NLQEAP----------QKTQPESQ--------EGRQPGKLSS-----PSQVH--Q-KGIENILEEHLIR-KMREISGGEIP-SAVDRSQEPSHLKNSE-DQSEIKDNQLFWGLPS-LHSESLKHEAA-NSVNSYP-----ERDDFH--------------------RIAEASTGRESSNLTYP----IPLL---------LPESD-QQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQT--VPQSQ----IKPDSPTDSKAQTQ-----SRLPFLPSSPQ---SQLR-----ICGVRFHSL-KDEGQPLAPYEL------------------------------------------------QQLEYNL------LQKTLQ---GFLGLPTLTQRFQEGFGPSPPKISSTRH-----SSKAHAPKKIL--PGDFPFNYKLERKLEHHLRKRLIQRR-----WGL-PQRI-RESLSFMNPHSKI-------------------PEVPEA-R--NSHG----LSW------------------ISHYKFNTNS-LSG---LGLSQ-TSSFHKKPLESHSL---K-AKDV--KVQ-GQCPGIG--------QRDHIQG----DS-SGALM-SRVHS-NSETDPELQ--------LRDMSGKISK-----ASLVKQCQ-RECESFLQEQLGR-NTKEISRGEMS-SAADRQEPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGCSS-----MFVFFNGITN----------------TSLF----QESPVLPPP----QPLS---------LLSTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLPQTLPQGQ----SPHLTEVQSQAQHQ-----SPLPALLPSPP---FLIK-----ICGVCFHRP-QNEARSLTPSEI------------------------------------------------NHLECNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNLTLVRK-----SFKVHVPIAII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------LELSVS-E--SIQG----PLH------------------SSSVEGQSLNVLKK---FGSST-PGTFHERSSNMLSL------ENV--GNYQGYRQENG--------PKNHLLH----DP-ETSSD-ENPRS-NSERDLDTH--------MMHLSENHS--------GESLGQ-KQLENALTVHLSK-KFEEINEGRMP-GTVHSSQEPPYSKCFE-DHLEQKYVQLFWGLPS-LHSESLHPTVL-VQRGCSS-----MFVFFNGITN----------------TSLF----QESPVLPPP----QPLS---------LLSTQ-AL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLPQTLPQGQ----SPHLTEVQSQAQHQ-----SPLPALLPSPP---FLIK-----ICGVCFHRP-QNEARSLTPSEI------------------------------------------------NHLECNV------LQKVQE---SVWGLPSVVQKSQEDFCPPAPNLTLVRK-----SFKVHVPIAII--PGDFPLSSEVRKKLEQHIRKRLIQRR-----WGL-PRRI-HESLSLLRPQSKI-------------------LELSVS-E--SIQG----PLH------------------SSSVEGQSLNVLKK---FGSST-PGTFHERSSNMLSL------ENV--GNYQGYRQENG--------PKNHLLH----DP-ETSSD-ENPRS-NSERDLDTH--------MQKLSDPRILQ-ESFQKNYSQLFWGLPS-LHSESLVANAW-VTERSYTL--HSPPFLFNGISN----------------VCPIQRETTMSPLLFQA----QPLP---------HLGPE-SQPFISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPQFR----PIPMAQAEAQAHLQ-----SSFPVLSPAFP---SPIN-----NSGVACPAS-QNKLQALCLPET------------------------------------------------QHPEWPL------LRKQLE---GGLALPSRVQKSQDVFSVSTPNLPQESL------------PSIL--PENFPISPELRRQLEQHIQKWFIQH------QGN-LGRI-QESLDLMQLRDES-------------------SGTSQA-K--GKPR-----PW-Q----------------SSTSTGESSKEAQK---VK---------------FQ-----LEGDP--CPHLGQILGQT---------PQNLSR----GM-ESFPG-KVLGA-TSE-ESERDLR--------KPLRSDSGSD----LLRRIER-NRIENVLKAHVRR-KLGQMNEGFIP-VRVRRSQQPPYSKCSE-DHLEQKYVQFFWGLPS-LHSESLNSNVL-LQCGCSS-----MFVFFNEIAS----------------MSTF----QEPPVLPHL----QPLS---------LPITQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLCQTLPQGQ----SL--------SQHP-----SPLTVQLPSPL---FQIG-----ICGVCFHKS-QNEAQSLTPSEI------------------------------------------------NHLEWNV------LQKLLE---SVWGLPSVVQKSQEDFCSPAPSLGLV-K-----SFKACCPISII--PGDFPLSAEFRKKLEHHIQKRLIQHR-----WGL-PRRI-HESLSLLRPQSPI-------------------VEISES-E--NSEG----PLH------------------KSLVEGQSHNDLKN---FKSRK-PRSFHKRSSNMLSL------ENV--GKFQGYSQENG--------PKDHLLH----EP-ETSSE-KDLSS-NSESNLEGH--------MMHLPGNDL--------GVSLGQ-KQLANALTVHLSK-KFEEISKGQVP-WSVRSSQQPPYSKCFE-DYLEQKCVWFFWGLPS-LHSESLNSNVL-LQCGCSS-----MFVFFNEIAS----------------MSTF----QEPPVLPHL----QPLS---------LPITQ-PL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLCQTLPQGQ----SL--------SQHP-----SPLTAQLPSPL---FQIG-----ICGVCFHKS-QNEAQSLTPSEI------------------------------------------------NHLEWNV------LQKLLE---SVWGLPSVVQKSQEDFCSPAPSLGLV-K-----SFKACCPISII--PGDFPLSAEFRKKLEHHIQKRLIQHR-----WGL-PRRI-HESLSLLRPQSPI-------------------VEISES-E--NSEG----PLH------------------KSLVEGQSHNDLKN---FKSRK-PRSFHKRSSNMLSL------ENV--GKFQGYSQENG--------PKDHLLH----EP-ETSSE-KDLSS-NSESNLEGH--------MMHLPGNDL--------GVSLGQ-KQLANALTVHLSK-KFEEISKGQVP-WSVRSSQKLSDPRILK-EHFQKNYSQLFWGLPS-LHSESLVANAW-VSERSYTF--QSPPFLFNGIPN----------------VRPVQTETAMSPLLFQA----QRLS---------HLRPE-SQPFISP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQFQ----LSPMAQAEAQARLQ-----SSFPVQSSAFA---SSIN-----NSGVACPAS-QNKAQALTLPEM------------------------------------------------QRPEWS--------SKQLE---GELALPSRVQKPQDVFSASTPNPPQDSL------------TAIV--PENFPVSPELRRQLEQHIQKWLIQH------QSN-LGTT-QEAPDLMQPREKS-------------------PGTSQA-R--GKLR-----PL-Q----------------SSMCTGESGKDIQK---VT---------------FQ-----LERNP--CTPLGQILGQT---------PQNLAR----CM-ESFPG-KVLGA-ASE-ELERDLK--------MPSRRHSESD----LLRRTER-NRIENILKAHVGM-KLGQINEGLIP-ICVRRSQQLLYVKTLG-GNLQQKYSQLFWGLPS-LHSESLVATLL-VSSSSSPL--ESHFVLFNGVCN----------------GSSVKMHDQESPPHLHS----HPLP---------LPHVH-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTKPKSQ----PLPFTQVQPQVNLQ-----SRLPILPSSPP---SQIR-----DCGVSFHRL-QNESDFHIATEN------------------------------------------------QHLEWHV------LQKQQE---SLWGLVPMLHKSQEATCPRALNLPLVNQ-----SSHACVPVSII--PDHFHITSEPQEKLELHVPRRLIPRW-----CLQ-ACRN-LESLALMEPQYKL-------------------IEVSQQ-R--GRHV----HLQ------------------LSELNGQHSKDLGM---TELGL-PGSFHERVPTKFQL---R--DDM--RKNLGYILEKS--------PEDRPQG----AS-ECYLV-QGLRP-AL--GTQSN--------CVCNSRNHSSYELLNVSRKDIDR-NQIKTILRLHVST-KSWQISAGRIP-VGVCRSQQPPYPKSLE-DHLQQKCIQLFWGLPS-LHSESLPSAFH-VSGDGSS-----VFI-FNRNSN----------------FSAD----QESPVHPHP----LPLS---------LPEIQ-PE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPQTLPPSQ----PLPLTEVQPQVHPQ-----SPLPVIPSSPL---SQIR-----ICGVCFHKP-QNEPECLTSSEI------------------------------------------------QQLEWNM------LQKQQE---NLWGVPSVVQRSKEDSCLPAPSISYHQVPRGPGAPRAHASISIP--PGEFPLSDEIRKKLEHHLRKRLIQHR-----WGL-PRRI-TESVSLLMPPREF-------------------LEISEA-E--SNYG----VSL------------------ISVLKGQSSKNL-S---VGLSQ-PGSIHERDSEML-----QQEADV--GKDQGQSLEHH--------PKDHLLN----DT-KSSSD-KDLEY-DSEKDLNSQ--------MPSLSEENLR-----VSAGSLGQ-RQLENALKVHLSK-KFEEINEGKLP-GTVNSSQQPSHLKNSE-GQSEIKDIQLFWGLPS-LHSESLKHEAA-NTGNSYP-----GRDYFN--------------------KVAQASTGSHSSNLTYL----IPLP---------LPESD-QQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQI--VPQSQ----IMPDSLANSKAQPQ-----SLAQFLPPSPQ---SQLG-----ICGVRLHSL-KNEAQPLTPCEI------------------------------------------------QQLEYNL------LQKALQ---SFLGLPTLAEKFQESFCPPPPKISSTRN-----SSKVHAPKTIL--PGDFPLSHTLERKLEHHLRKRLIQRH-----WGL-PHRI-LESLSFLSPHSEI-------------------PEAPKP-R--DTHG----LSW------------------VSPYKFNANTNLPS---SGVSQ-SGRSCKKPLESHPP---Q-EKDI--NIQ-RHRPGIN--------QKDPIQC----KS-CGATK-STVHS-NSETDPELQ--------LGNTSGNISK-----ASWVKQCQ-KECETFLQKRLGK-NTKEISGSEMP-SAVDSSQPLPHSKTFE-DHEELQPSLLFWGPPS-LHSETLSPTTT-NAYDRSS-----ALVCFN--------------------SMAEASIADYSHGCMLP----TPLH---------AY--R-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TWLQTTPQSH----PQRDPPAELQPQPQPQPQSRVSVLTF-SRQ---SELR-----DCGVHFHRP-QGDEQPLSPSEM------------------------------------------------QCLEYNI------LKKEQE---RVWGLPLVVKKSQDTFCPSPPKVLLGSR-----SSKACTPRPIL--PGDFPLTSELEKKLEHHLRKRLIQHR-----WGL-PDRI-DKSLSLLSPQSEL-------------------IDFSES-Q--KNQG----LSW------------------ITFFKYQGNKDSQV---LSGGS----SRSWMPKRHSL---R-ETRV--KER-TYSQDQG--------HKDQSRG----NNFQEASQ-NSVQS-HLKTHWKSR--------TGRQPPKFSS-----PSQVKQYQ-RGIEKALEKHLNK-KIREISRGEIP-ITVNRSQGLAQVQSSG-GQLEAMPMQHFWGLPY-LHSESVSCITT-LSSHCSS-----MCIWFN--------------------------RTTDSPALAPP----SPLP---------LPERQ-PQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLTQSQ----SQSIQLATPHSQLQ-----T-LPGPSPSSQ---SQVR-----VCGVYFRRS-Q-EAKALLQSEI------------------------------------------------HHVEYNM------MAKEPE---REWALPSVVQKPQEELRLLPSKLSLAIK-----SSKLQTPRSVP--PRDFPLADGFQKKFEQHLRKRLILQR-----WGL-PQGI-YKSQLWANPDPP-----------------------EAS-K--SSSG----LSD---------------------FKHKDNKARPN---TVSNQ-SGSPQEK---SVSI---E-RKIV--KAH-EQTLEII--------QK-YICS----NS-KTAVD-NGLPS-DHEINLQSH--------LGSLSDQPSE-----TSQVSQCR-KKFETPPKEHLKS-HIDGTNEGQVP-ITMQVLCVKIPE-GDLGQNHSQLFWGLPS-LHSESIMATLL-VPVSSYSP--EPCLVLFNGVCK----------------AASGPVLSHGFPALPQP-----------------LTLVH-PQPLPKVA--P--QPQ-TLTEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQ----AHMQ-----SPWSSMA-LPS---LPYG--------SALQIP-QTRAVSDVINGK------------------------------------------------GHLQYHL------VQNPQD---SLWGLVPECQQYETALGLPVHSFPVGSQ-----SSQTYVSVP-G--SGLFHFSSEHQNNLDPYGPNNLTSPS-----CFEL-CSR-PGVPEVMNTQFKP-------------------TGVSSY-N--YKYA-----KS-Q----------------CCVHWGNICADPGN---GELSH-SESYCMKVPMKPQL---R--KDA--AKNLGQILGKC--------PLDNTQM----IS-GCCIL-NGLKA-IPET--EGELA--------YHSRTDLENEQLTISKKNLDQ-RHMRSILRLHMSR-KCWQITMGRIP-IMVCCSQKLSYPKLSE-DHFQQKYDQLFWGLPS-LHSESLVAAAW-IPQTTSTL--PSPFFLFNVISS----------------VYPIQLQDKMSPMLPHT----HPLS---------YLDLQ-SPPLILSPL--EFQTP-ALN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LP-----VLVPSSL-SYN------R-----DFGTSYSQS-QSKPQY-FSTEI------------------------------------------------KYNERPS------LAKQIE---NRSTLPLMVQKPQEAYDILASNPSQD-W-----V------VSIL--PGNFPISCELREKLEQHIQKWLIQHQ-----WNF-PHKIQ-VSEKMKELQNTV-------------------IGNCQT-R--DKPG-----TS-Q----------------A---LGEHSNEGQK---RKF---------------QL---E--KES--GKNLGPILGKI--------SK-DPIR----GL-EKTTA----------------------------------------------N-QHLSYSKTSE-DQLEDKHTQSFWGLPS-LHSESMNSIAT-VLTDSSP-----ISGCFN--------------------------RFSDSPMLTHR----TTLP---------LSESQ-LH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLSQSLSQSQ----SQPVPQANLQAQLQ-----PPNPVLSP-P----SQLR-----ICGVYFHSP-QNEAEPLEPSAI------------------------------------------------HCLEYNI------LKKEQE---RVWGLPTVVKNSQQEFCPPPPNPSLVSQ-----LSKTHVPKSIS--IENCLITSELQKKFEHHLRKRLILQH-----WGL-PKRI-RESLLWINPQAEF-------------------PESHSS-K--SNYG----LSW------------------IPFFKQQRKKDLRN---TILNQ-PGSFPAKQL--------E-EKLL--KLCSKQGLEMV--------QKQQTWS----NT-KSTLD-SGLQS-DCETNLQCH--------SDSLSCKPLG-----TSEVSQCQ-KKLETSLKEHLTT-RLNETIEGQIT-STMSRSQQPPHLKNCE-DQSETKDTQLFWGLPF-LHSESLKHEAA-NTGKSYP-----GRDYFN--------------------NVAKASTGGDSSNLTYP----IPLP---------LPESD-QQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQI--VLQSQ----IKSDSLANSKAQPQ-----PLSQFPPPSPQ---SQLR-----ICGVRFHSL-KNEAQTLTPCEI------------------------------------------------QQLEYNL------LQKALQ---SFLGLPTLTPRFQEGVCSPPPKISSTRN-----PSKVHAPKTIQ--PGDFPLSHTLERKLEHHLRKRLIQRH-----WGL-PHRI-LESLSFMSPHSET-------------------PEAPKP-R--DTHG----LSW------------------ASLYKFNDNKNLPS---FGVSQ-SGGSLKKPLEIHPP---E-DKDI--NVQ-RHCPGIS--------QRDPIQC----KS-CGATK-SSIHS-ISETDPELQ--------PGNMSGKFSK-----ASWVKQCQ-KECETFLQKQLGK-NTREISGSEMP-SAVDSSQPLPHSKTSE-DQEELQAAQLFWGPPF-LHSEALSPTTT-NAYDRSS-----AWVCFN--------------------SMAEAAIADYSHGCMLP----TPLR---------AY--R-PQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TWLHAAPQSQ----PQRDPPAELQPQP--QPQSRVSVLTF-SHQ---SELR-----DCGVHFHRP-QGDEQRLGASEM------------------------------------------------QCLEYNI------LKKEQE---RVWGLPLVVRKSQDTFCPSPPKVLLGSR-----SSKACTPRPILPLPGDFPLTSELEKKLEHHLRKRLIQHR-----WGL-PHRI-DKSLSLMSPQSEL-------------------IDFSES-K--KSRG----LSW------------------ITLFKYQGDKDSQA---LSGGS----SRSQMPNSHSL---R-ETGV--REW-TGSQERG--------HKDQPRG----NSLQEVSQ-SSVQS-HWRMHQKRL--------AGRQPPEFSS-----PSQVKQYQ-KGIEKILEKHLSK-KSREISRGELP-MTVDRSQGLAQVQPSG-DQLETMPIQHFWGLPY-LHSESMSCITT-LSSHCSS-----MCIWFN--------------------------RTTDSPALAPC----SPLP---------LPERQ-PQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLTQSQ----TQSIQLATPHSQLQ-----I-PPGPSPSSQ---SQVR-----VCGVYFRRS-Q-EAKALLQSEI------------------------------------------------HHIEYDM------MVKEPE---RAWALPSVVQKPQEELCLLPSKLSLAIK-----SSKFQTPRSVP--PRDFPLTDGFQKKFEQHLRKRLILQR-----WGL-PQGV-YKSQLWASPDPT-----------------------ESS-K--SNSR----LSG---------------------FKHKDNKGGPN---TVSNQ-SGSPQEK---SVSI---E-RKTV--KAQ-EQTLEII--------QK-YICS----NS-KTDLD-NGPPS-VQEVNLQ----------SGSLSDKPSE-----TSQVSQCR-KKFEAAPKEHLKS-HIDGTSEDQVP-VTLSGQVLCVKIPE-GDLGQKHSQLFWGLPS-LHSESIVATVL-VPVSSYSP--EPCLVLFNGVCK----------------AATAPVLSHGLPALPQP----HTW---------PLTLVH-PQPFPKVP--P--QPQ-TLAER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQ----AHMQ-----SSSSSMT-LLS---PPCG--------CALQIP-HTRTASDVFNGK------------------------------------------------EHLQYHL------LQNPQD---SLWSLVPECQRYETALELPVHSCPMGSQ-----SSQTYVSIP-G--SGPFHFSSEHQNNLDPYGANNLTSPW-----CFEL-CDR-PGVPEVMNTKLKP-------------------TGVSSH-C--YKYT-----TS-Q----------------CSMHWGNICADSGN---GELSH-LESYCVKVPMKPQL---R--KDA--AKNLGQILGKC--------PLDNPQM----SS-GCCIL-NGLKA-IPKT--EGESA--------CHSRTGLDNGQLTISRKNLDQ-RHTRSVLRLHMSR-KYWQITMGRIP-IMVCCSQKLSYPKISE-DHFQQKYDQLFWGLPS-LHSESLVAAAW-IPQTTSTL--PSPFFLFNVISR----------------VYPIQLQDKMSPMFPHT----HPLS---------YLDLQ-SSPLILSPL--EFQTP-ALNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHFQSHFP-----VLLPSSL-PYN------R-----DFGTSYSQS-QSKPQY-LPTEI------------------------------------------------KYNERPS------LAKQIE---NRLTLPLMVQKPQEAYDI---NPSQD-W-----V------VSIL--PDNFPISCELREKLEQHIQKWLIQHQ-----WNF-PHKIQ-DSEKMKELHNTV-------------------IGNCQI-R--DKPG-----TS-Q----------------A---LGEHSNEGQK---IKF---------------QL---E--KES--GKNLGPILGKI--------SK-EPIR----GL-ENTIV----------------------------------------------QQPSHLKNSE-DQSEITDIQLFWGLPS-LHSESLKHEAA-NTGNSYP-----GRDYFD--------------------KVAQASTGSHSSSLTYS----TPLP---------LPESD-QQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQI--VPQSQ----IMPDSLANSKAQPQ-----SLAQLLPPSPQ---SQLG-----ICGVRFHSL-KNEAQPLTPCEI------------------------------------------------QQLEYNL------LQKALQ---SFLGLPTLTETFQESFCPPPPKISSTRN-----SSKVHAPKTIL--PGDFPLSHTLKRKLEHHLRKRLIQRH-----WGL-PHRI-LESLSFLSPHSEI-------------------PEAPKP-R--DTHG----LSW------------------VSLYKFNANTNLPS---SGVSQ-SGRSCKKPLESHPP---Q-EKDI--NVQ-RHRPGIN--------HRDPIQC----KS-CGATK-STVHS-NSETDPELQ--------LGNRSGNISK-----ASWVKQCQ-KECEAYLQKHLGK-DTKEISGSERP-SAVDSSQGLAQVQSSG-GLLEAMPMQHFWGLPY-LHSESMSCITT-LSSHCSS-----MCIWFN--------------------------RTTDSPALAPP----SPLP---------LPERQ-PQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLTQSQ----SQSIQ-------LQ-----T-LPGPSPSSQ---SQVR-----VCGVYFRSS-Q-EAKALLQSEI------------------------------------------------HHLEYNM------MAKDPE---REWALPSVVQKPQEELSLLPSKLSLAIK-----SSKLQTPRSVP--PRDFPLADGFQKMFEQHLRKRLILQR-----WGL-PQGI-YKSQLWANPDPS-----------------------EAS-K--SSSG----LSG---------------------FKHKDNKAWSN---TVSNQ-SGSPQEK---SVSV---E-RKTV--KAH-EQTLEII--------QK-YICS----NS-KTALD-NSLPS-DHE-NLQGH--------SGSLSDQSSE-----TSQVSQCR-KKFETPPKEHLKS-HIDGTNEDQIP-VTLSQVLCVKIPE-GDLGQKHSQLFWGLPS-LHSESIMATLL-VPVSSYSP--EPCLVLFNGVCK----------------TASAPVLSHGLPALPQP-----------------LTLVH-PQPLPKVA--P--QPQ-TLTEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQ----AHMQ-----SPLSSMA-LPS---LPCG--------SALQIP-QTRTVSDVLNGK------------------------------------------------GHLQYHL------VQNPQD---SLWGLVPECQQYETALGLPVHSFPVDSQ-----SSQTYVSVP-G--SGLFHFSSEHQNNLDPYGPNNLTSPS-----CFEL-CNR-PGVPEVMNTQFKP-------------------TGVSSY-C--YKYA-----TS-Q----------------CCLHWGNICADPGN---GELSH-SESYCVKVPMKPQL---R--KDA--AKNLGQILGKC--------PLDNTQM----IS-GCCIL-NGLKT-IPET--EGESV--------CHSRTSLENEQLTISKKNLDQ-RHMRSILRLHMSR-KCWQITMGRIP-IVVCCSQKLSYPKISE-DHFQQKYDQLFWGLPS-LHSESLVAAAW-IPQTTSTL--PSPFFLFNVISS----------------VYPIQLQDKMSPMPPHT----HPLS---------YLDLQ-SPHLILSPL--EFQTP-ALN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LP-----VLLPSSL-PYN------R-----DFGTSYSQS-QSKPQY-LPTEI------------------------------------------------KYNKRPS------LAKQIE---NRSTLPLMVQKPQEAYDILAPNPSQD-W-----V------VSIL--PDNFPICRELREKLEQHIQKWLIQHQ-----WNF-PHKIQ-VSEKMKELQNTV-------------------IGNCQT-R--DKPG-----AS-Q----------------A---LDEHSNEGQK---RKF---------------QL---E--KES--GKNLGPILGKI--------SK-DPIR----GL-EKQHLSYSKTSE-DQLEDKNTQSFWGLPS-LHSESMNSIAT-VLTDSSL-----ISGCFN--------------------------RFSDSPMLTHH----TTLP---------LSESQ-LH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLSQSLSRSQ----SQPVSQANLQAQFQ-----PPNPVLSP-H----SQLR-----ICGVYFHSP-QNEAQPLEPSAI------------------------------------------------HCLEYNI------LKKEQE---RVWGLPTVVKNSQQEFCPPPPNPSLVSQ-----ISKTHVPKSIS--IEKCFITSELQKKFEHHLRKRLILQR-----WGL-PKRI-RESLLWINPQAEL-------------------PESPSS-K--SNYG----LSW------------------IPFFKQQSKKDLHK---TILSQ-PGSFPAKQL--------E-EKLL--KLCSKQGLEMV--------QKQQTWS----NT-KDTLD-NGLQS-DCETNLQCH--------SDSPSCKPLG-----TSEVSQCQ-KKLETSLKEHLTT-RLNETIERQIT-STMSGS