Query Results 

------------------------------------------------------------
------------------------------MKRSLGKMLRI-GE-KEPQGVVYHGVEDS-
-------MPDSKDFKVVFEG-NECRLQHFIKNRW-KLS--KYEE

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

ANVSPLHHAAAEGELE
LMK-----MIISGSSCEVLNVMDNFGNTPLHWAAENNQVESAKFLLTEGANPNLRNSSMM
APLHLAVQGM-YNEMTKVLIEHSSTNINLEGENGNTAVMITCSKDNSE-ALEILLKKGAK
LCKSNKWGDFPVHQAAFSGAKKCMELILQF-GEEDGYSRQSLINFL--NNKQASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGNLEMIKMCLDNGAHIEQIEN-GKCMALHFAATQGATEIVKLMISSYSGSSDIVNAVD
GNHETLLH-R--ASLFDHHELADYLISVGAD--MNVTDSEG-RSPLVLATASASWNIVNL
LLSKGAKVNIKDHLGRNFLHFTVQQPHGLKSLRPEFMQMQEI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KALVMDEDNDGCTPLHYA
CKQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQNITDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLNYDADIILNKQWASFLHIALHNK
RKEVVLTTIRNKRWDECLKVFNHCSP----SNKCPVMEMIEYLPECMKILLDFCMIPSTE
DKSCQDYHIEYSFRYLHCPLGLTKKITPEQEVQYEPLPILNVMVQHSRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVNIKPGTAFNSTG---------IINE

PF00520 // ENSGT00920000149074_1_Domain_48 (898, 1149)

THD
-----HLEILDTT---NSY--------------PIKVCMILVFLSSIFGYCKEVVQIFQQ
---KMNYFLDYNNALEWIIYTKSIIFVLPLFVN--IPASVQWQCGAIAI-FFYWMN-FLM
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNVQEAFSSPL
LSLIQTFTMMLGDVNYRDAYLEPFLRNELAYPVLSFAQLIAFTMFVPIVLVNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIVVYPNRPRHGR-M--LRLF
HYFFGIQETR-QEIPNTDT--CLELEMLKQKYRLKDLSTLLEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDRF-KKERLEQMNSKWNFVLKAVKAKPHCPTSHSLQ---

------------------------------------------------------------
------------------------------------------------------------
------------LFEVVFEG-NANELQSCLKKPK-KPH--KYDD

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 204)

VNASPLHYAAEEGDIG
LME-----MIINDSSCEVLNVMD

ENSGT00920000149074_1_Linker_0_2 (204, 205)

N

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

DGNTPLHWAAEKNQVESVRFLLSKGANPNLQNNSMM
APLHLAVQGM-HNEVVKVLIEHSGTNINLEGENGNTAVIIACSRDNSE-ALQILLRHGAK
PCKSNKWGCFPVHQAAFSGAKKCMEIILKF-GEENGYDRQFHINFV--NN

PF00023 // ENSGT00920000149074_1_Domain_12 (351, 383)

GKASPLHLAV
QSGDLGMIKMCLDNGAQVELMEN-GKCTALHFAATQGATEIVKLMINSYSGSSDIVNAVD
GNQETLLHRQ-VS--YSHSVYRLSVF

PF00023 // ENSGT00920000149074_1_Domain_19 (447, 459)

SQGAD--INSTD

ENSGT00920000149074_1_Linker_19_21 (459, 460)

S

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATASASWNIVNL
LLSRGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

HLGRNFLHLTVQQPYGLSNLQPEFMQMQHIKELVMDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

DGCTPLHYA
CRQGVPASVNNLLGFNVSIHSKS

ENSGT00920000149074_1_Linker_22_23 (564, 565)

K

PF00023 // ENSGT00920000149074_1_Domain_23 (565, 602)

DKQSPLHF-----AASYGRINTCQRLLRDMNDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLRKGALF---LSDHSGWTALHHASLGGYTQTMKV
ILDTNLKCTTDQVDEDGNTALHLAAREGHAKAAALLLNYDADILLNRQQASFLHLAIHNK
RKEVVLMTIRNRRWEECFRAFSHNSP----SNKCPVVEMVEYLPECMKVLLDCCMTPSTE
DKSCRDYHIEYNFRYLQCPLEFTKKN--AQDVTYEPLTTINTMVHHNRIELLNHPVCKEY
LLMKWLAYGFRAHIMNLGSYCLGLLPMTFLVVNIKPGMAFNSNW----------------
-----HHSNFLFK---DSY--------------SIKVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

ILVFLSSLFGYCKELVQIFQQ
---KRNYILDQSNGTEWVIYTTSIIFVSPLFIS--IPAHVQWQCGAIAI-YFYWMN-FLM
YLQRFENCGIFIVMLEVIMKTLLRSTVVF--IFLLL---AFGLSFYV-LLSIQDAFSTPL
LSIIQTFSMMLGDINYRDAFLEPFLRNELAYPLLSFIQLITFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTNLEKKLPLWFLRKVDQKSIIVYPNRARYSRGL--LCIF
HQIFCTQEVR-QEIPNADT--ALEVEILKQKYRLKDVTSLLEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDRY-KREQQEQRNSKWNSVLKAVRAR-------------

------------------------------------------------------------
------------------------------MKRSLKKMWRP-GEKKEPQGVLYEDVPDDT
DDC-------KESLKVVFEG-SACGFQNFK-NQK-TLN--

PF12796 // ENSGT00920000149074_1_Domain_0 (161, 236)

RCDNED-ISLHYAAAEGQVE
LME-----KITRDSSFEVLNAMDDYGNTPLHCAVEENQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHIAVQGM-HNEVMKVLLEHRSIDINLEGENGNTAVIIACIKNNSE-ALQILLTKGAK
PCKSNKWGCFPIHQAVFSGSKECMEILLRF-GEEHGYNRQLHINFV--NNGKASALHLAV
QNGDLEMIKMCLDNGAQIDLVEK-GRCTALHFAATQGATEIVKLMISSCSGGMDIVNTTN
GSGETMLHR---ASLFDHHELADYLISVGAD--INSIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVNIKD

ENSGT00920000149074_1_Linker_21_22 (493, 548)

NFGRNFLHLTVQHPYGLKNLQPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGGPG

PF12796 // ENSGT00920000149074_1_Domain_22 (548, 631)

SVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDITDTRLL
NEGDLHGMTPLHLAAKNGHEKVVQLLLKKGALF---LSDHNGWTALHHASVGGYTQTMKVILDTNLKCT-DRLDDDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTTIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLPSTEDKSCRDYYIEYNFKYLQCPLEFTRKTTPTQDITYEPLTALNAMVQNNRIELLNHPVCKEYLLMKWMAYGFRAHMINLGSYCLGLIPMTFLVINIKPGMAFNSTG---------IINETSD-----HSEILDTR---DSY--------------LIQTCMILVFLSSIFGYCKEVVQIFQQ---KRNYFMDINNIIEWIIYTTGIIFVLPLFIE--IPAHVQWQCGAIAI-YLYWMN-FLLYLQRFENCGIFIVMLEVILKTLLRSTVVF--VFLLL---AFGLSFYV-LLNLQDAYSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAYPVLSFAQLIFFTLFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLHKVDQKSTIVYPNKPRSGGILF--HIFFFLFCTGEIR-QEIPNADT--SLEMEI

PF12796 // ENSGT00920000149074_1_Domain_23 (548, 631)

SVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDITDTRLLNEGDLHGMTPLHLAAKNGHEKVVQLLLKKGALF---LSDHNGWTALHHASVGGYTQTMKV
ILDTNLKCT-DRLDDDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTTIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLPSTE
DKSCRDYYIEYNFKYLQCPLEFTRKTTPTQDITYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWMAYGFRAHMINLGSYCLGLIPMTFLVINIKPGMAFNSTG---------IINETSD
-----HSEILDTR---DSY-------------

PF00520 // ENSGT00920000149074_1_Domain_48 (933, 1149)

-LIQTCMILVFLSSIFGYCKEVVQIFQQ
---KRNYFMDINNIIEWIIYTTGIIFVLPLFIE--IPAHVQWQCGAIAI-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--VFLLL---AFGLSFYV-LLNLQDAYSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAYPVLSFAQLIFFTLFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLHKVDQKSTIVYPNKPRSGGILF--HIF
FFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEH-------

------------------------------------------------------------
------------------------------MKRSLRRILRP-EERKEVQGVVYCGVGEDM
DC-------SKESFKVDIEG-DMCRLEDFIKNRR-NLS--

PF12796 // ENSGT00920000149074_1_Domain_0 (161, 236)

KYEDENLCPLHHAAAEGQVE
LME-----LIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 240)

NRNM

PF12796 // ENSGT00920000149074_1_Domain_6 (240, 303)

M
SPLHIAVHGM-YNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILVY-GEKAGYSRESHINFV--NHKKASPLHLAV
QSGDLDMIKMCLDNGAHIDMMEN-AKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVD
GNQETLLH-R--ASLFDHHDLADYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLRNLQPEFMQMQH

PF12796 // ENSGT00920000149074_1_Domain_22 (522, 593)

IKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKTKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNK
RKEVVLTTIRNKRWDECLQVFTHDSP----SNRCPIMEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLSMTKKVAPTQDVIYEPLTILNVMVQHNRIELLNHPVCREY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTG---------IINGTSS
----THEERIDTL---NSF--------------PIKIC

PF00520 // ENSGT00920000149074_1_Domain_48 (939, 1149)

MILVFLSSIFGYCKEVIQIFQQ
---KRNYFLDYNNALEWVIYTTSIIFVLPLFLE--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFSLSFYV-LLNFQDAFSTPL
LSLIQTFSMMLGDINYRDAFLEPLFRNELAYPILTFGQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQRSTIVYPNRPRHGR-M--LRFF
HYFLSKQETR-QEVPNIDT--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKERLEQMHSKWNFVLNAVKTKTRCSISHPDF---

------------------------------------------MSIFMKKGARA-------
--RGE--------------QLHQVASGVGSMKRSLRKMWRP-GEKKESQGVVYEDVQDDT
DDC-------KETLKVVFEG-SAYGLQNCN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYASAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFV--NNGKASPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INKIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 523)

NFGRNFLHLTVQQPYGLKNLRPEFMQMQQI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KELVMDEDNDGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMNNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIVQTFSMMLGDINYRESFLEPYLRNELAHPFLSFAQLICFAIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGLLF-QHIF
YFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLRKMLRP-GEKKEPRGVVYEGVEDDM
EDG-------KDSFKVVFEG-SSCKLKNFVKKQN-RLR--KRDDVNASPLHHASEEGQVE
LME-----MIINESSCEVLNAMDS

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWATEKNQVESVKFLLSKGANPNLRNDNMM
GPLHIAVQHM-YHEVMKVLAEHSSTNLNLEGENGNTAVIIACSKDNSE-ALRFLLNKGAK
PCLSNKWGCFPVHQAAFSGAKQCMEIILKF-GEEHGHSRQSHINFV--NNGKA

PF00023 // ENSGT00920000149074_1_Domain_12 (354, 380)

SPLHLAV
QSGNLEMIKMCLESGAQIDLMEN-GKCTALHFAATQGATEIVKLMISSYTGDRDIVNAVD
GNQETLLHR---VSLFDHHDLAEYLISVGAD--INSIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 492)

-RSPLLLATASASWNIVNL
LLSKGAHVDIKDHLGRNFLHLTVQQPYGLKNLQPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLHFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDITDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSSHHGHFLHTNATFSSITNHNS-
SLSANMSLL-IFKRAE

PF00023 // ENSGT00920000149074_1_Domain_47 (677, 703)

QNTALHFAAREGHAKAVSLLLSYNAD

ENSGT00920000149074_1_Linker_47_48 (703, 952)

ILLNKQLASFLHVAIHNK
RKEVVLMAIRNKRWGECLKVFSHYSQ----NNKCPVMEMVEYLPECMKVLLDFCMTHSTE
DKSCQDYHIEYNFTYLQCPLEFTKKETSPQDVTYEPLTILNAMVQHNRTELLNHPVCKEY
LLMKWLAYGFRAHIMNLGSYCLGLMPLTFLVAKINPGMAFNSTG---------IINRTSN
-----HTEMLVTK---DSY--------------SIKVCMILVLLSSIFGYC

PF00520 // ENSGT00920000149074_1_Domain_48 (952, 1137)

KEVVQICQQ
---RRNYFWDQSNIVEWIIYTTSIIFVLPLFVG--IPAHVQWQCGAIAV-FFSWMN-FLL
YLQRFEHCGIFIVMLEVIMKTLWRSTIVF--IFLLM---AFGLSFYV-LLSVQDAFSDPL
LSVIQTFSMMLGDVNYRDSFLEPYLKNELAYPVLSFIQLIVFIMFVPIVLMNLLIGLAVG
DIAEVQKHAVLKRIAMQVELHTSLEKKLPLCFLRKVDQQFITVYPNKFRDSGGLL-LFTC
LFLAADCELLENLVPNKFDNCVFHSLKKKKKKKLKDLTSLLEKQHELIKLIIQKMEIIAE
TEDEDSHSSFQDRF-KKEQLEQRNSKWNCVLRAVKEKTQ-----------

------------------------------------------------------------
------------------------------MKCSLRKMWRP-GEKKEPQDVVYEDVPDDT
EDF-------KESLKVVFEG-SAYGLQNFN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHIAVQGM-NNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFM--NNGTATPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GCHETMLHR---ASLFDHHELADYLISVGAD--INKIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTR

PF12796 // ENSGT00920000149074_1_Domain_24 (599, 667)

LL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASVGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKIFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMSNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YFYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTVVYPNKPRSGGMLF--RIF
CFLFCTGEIR-QEIPNADK--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDDDSHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLWRLCQS--REKAATSSAYQGVVCEA
DAASV---ASQDVFKVISDG-SACRLRSFIKKNRSGLT--KVDE

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 234)

LNATPLHHAAEGGQIE
LMQ-----LIIDDSSSEVLNVMDSSGNTPLHWATRKNQVESVRLLLSRGANPN

ENSGT00920000149074_1_Linker_0_6 (234, 240)

ILNSNM

PF13637 // ENSGT00920000149074_1_Domain_6 (240, 295)

M
APLHMAIQSL-HNEIVKILVQHSSTDVNLEGEAGNTPIIVACYKDNPE-ALTFLIENGGK
ICKPNKTGCMPIHAAAFSGAKTCMEILLKK-GEELGHSAKTHINFT--NNGKCSPLHLAV
QSGDLEMIKMCIEFGAQIDLKQN-EKCTALHFAATQGATEIVKLMMSSYAGDESIIDAVD
GNKETLLHRT---ALFDHYELAEYLISTGAN--IDSVDTEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 492)

-RSPLLLATSCASWKIVNL
LLSKGANVSLK

ENSGT00920000149074_1_Linker_21_22 (492, 522)

DHLGRNFLHLTVLQPGGLQHLNEKFLQMEH

PF12796 // ENSGT00920000149074_1_Domain_22 (522, 592)

IKNLVVDEDNEGCTPLHYA
CRQGVALSVNNLLSLNVSIYSKSRDKKSPLHF-----AASYGRINTCQRLIRDMKDTRLL
NEGDKKGMTPLHLAAQNGHEKVVQFLLKRGALF---LCDYKGWTALHHAAFGGYTRTMQI
ILDTNVKCT-DKVDEEGNTALHLAAKEGHAKAVRLLLDYGAKILLNKAVASFFHEAIHNR
RKDVVSTVILHKRWEEAVLTFSHYSS----ANKCPLLEMIEYLPDSFKLVLDNCIIESSE
EKTSRDFYIEYNFRYLQCPLALNRKLKEAEDIFYEPLAILNAMVRHNRMELLSHPVCKEY
LLMKWMAYGFRAHLMNLGIYSLGLIPLTLLVTHIQPGRPLNGTE---------IYE----
--ARPLEYE-------DSY--------------FTR

PF00520 // ENSGT00920000149074_1_Domain_48 (937, 1148)

VCMCLVLIMSLLGICKEIFQLIQQ
---KLKYLLDYSNLLDWTIYSTSIIFVSSLFIN--TPAHLQWECGAIAV-YLSWMN-FLL
YLQRFENYGIYVVMFWEILRTLIRIAVVF--FFLIL---AFGLSFFVLLGSQ-QTYSTPL
LSVMKTFAMMLGDINYHDAFLDPLLSSELPYPFLSYTVLIIFTLLIPILLMNLLIGLAVG
DIAEVQKYAALKRIAMQVNLHTNLEKKLPFWFLSRVDQESITVYPNRPRYCGFMS---VF
QYCFGCEDST-TDAQSTDT--TLELEVLKQKYRLKDISTLLEKQHDLIKLIIQKMEIVSE
AEDEDSNDLFQHKF-RKRQLEHRNSKWDTVLKAVKSNVSNPSTEKSSSLL

------------------------------------------------------------
------------------------------MKRSLKKMLRP-GEKKESQGVVYQGVQVDM
DDS-------KESLKVVFEG-SSCRIRSFIKRQK-SIS--GKNERNSSPLHHAAAEGEVE
MME-----MIIKDSSCEVLNSMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 236)

YGNTPLHWAAEKNQVESVKFLLSKGANPNLRNCNMM
AALHIAVQAM-FNEVVKVLTEHSSININLEGENGNTAVILACTKDNSE-ALQILLNKGAN
QCKPNKWGCFPVHQAAFSGAKKCMEIILKY-GEEHGYSRECHINFV--NNGKASPLHLAV
QSGDLEMIKMCLDNGAHIELVED-GRCMALHFAATQGATEIVKLMISSYSGSTDIVNAVD
GN

PF00023 // ENSGT00920000149074_1_Domain_16 (423, 458)

HETLLHR---ASLFDHHELADYLISVGAD--VNVIDSEG-RSPLILATASASWNIVNL
LLSKGARVDIKDHFGRNFLHLTVQQPYGLNNLRPEFMQMQEIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIYSKSKDRKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LRTHPNWDSKINATMGTDFSMFSE
SIRQDLKWCVDYSFLQK

PF00023 // ENSGT00920000149074_1_Domain_47 (678, 703)

NTALHFAARDGHAKAVGLLLSHNAD

ENSGT00920000149074_1_Linker_47_48 (703, 951)

IVLNKKQASFVHLALHNK
RKEVVLTAIRSKRWDECLKVFSHRSP----SNRCPITEMIEYLPECMKIKLSFINLDHHK
DLMCGIFHIEYNFKYLQCPLEFTQKTKPSQAAAYEPLTALNAMVQHNRIELLNHPVCKEY
LLMKWMAYGFRAHMMNLGSYCLGLIPMTLLVVSIKPGMAFNSTA---------IINETSN
-----YSEILDST---HSY--------------PIKVCMILVFLSSLFGY

PF00520 // ENSGT00920000149074_1_Domain_48 (951, 1137)

CKEVVQIFQQ
---KRNYLSDFNNIIEWIIYTTSIIFVLPLFID--IPAHVQWQCGAIAI-YFYWMN-FLL
YLQRFENCGIFIVMLEVIMRTLLRSTVVF--VFLFL---AFGLSFYV-LLNLQDAFSSPW
LSIIQTFSMMLGDVSYQDAFLEPFLRNELAYPFVSFALLIAFTIFVPVVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSSGRL--FHLF
YYLFCNHETR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDKF-KKEQLEQRCSKWNSVLRAVKAKTQ-----------

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKEPQGVVYEDVQDDT
DDC-------KETLKVVFEG-SAYGLQNYN-KQK-KLK--RCDDMDTFFLHDAAAEGQIE
LME-----KITRDSSLEVLNEMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 236)

YGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMM
APLHLAVQGT-HNEVMKVLLEHKTIDINLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFV--NNGKA

PF00023 // ENSGT00920000149074_1_Domain_12 (354, 379)

SPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INKIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

NFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 562)

DGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDL

PF00023 // ENSGT00920000149074_1_Domain_28 (606, 631)

HGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------IINETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYC

PF00520 // ENSGT00920000149074_1_Domain_48 (952, 1137)

KEAGQIFQQ
---KRNYFMDMNNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLISFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGLLF-Y-IF
YFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------------------------------------
---------------MVSDG-STCRLQTSVQKSVEEPV--PHDQLDATPLHHAAGRGQLD
LLE-----VGFHRATWEELNVTDAS

PF00023 // ENSGT00920000149074_1_Domain_2 (206, 235)

GNTPLHWATRQNQVQSVQLLLGRGANPNLRKN-CM
APLHLAVARPATTTWVKVLLQHPGTDVDLEGENRNSAIMFACHKDNSE-ALQLLVERRAK
ACKSNKWGYFPIHLAAFSGAKKCMDIILEYGGEKEGCSRIDHINLL--NHAKS

PF00023 // ENSGT00920000149074_1_Domain_12 (354, 380)

SPLHLAV
QSGDLEMIQKCLKHGAQVDLEED-GRGRRKRGAGLSGAGGSERLDFR--WGRRKWRELTS
G-CLLFLS-P-RASLFDHYDLADYLISKGAN--IDSIDSEG-RSPLLLATASASWNIVNL
LLAKGANVEIKDHLGRNFLHLAVLQPHGLNHLRQEFLQMQGIKALVKEEDVEGCTPLHYA
CRQGVPLSVNNLLGLNVSINSKSKDKKSPLHF-----AANFGRINTCKRLLRDVTDSRLL
NEGDQE

PF00023 // ENSGT00920000149074_1_Domain_36 (607, 631)

GMTPLHLAAKNGHDKVVQYLIRKGALF---LSDHRGRTALHHAALGGYTQTLHV
ILDTNLKCT-DQLDEDGNTALHLAGREGHAKATSLLLHSGAQIILNKSTASFLHEAIHNR
RKDVVVTAIRNPRWEECFMAFSHSSP----TNKCPVLEMVEHLPECMKMLLDSCMVDSSE
EQTGQDFYIQYNFRYLQCPLELKKQVAEEKNIEYEPLVALNSMVRHNRIELLNHPVCKEY
LLMKWMAYGFRAHIMNLALYCLGLIPLTLLVINIKPGLAFNSTG---------ILNATGY
-----SSQSLDTE---NSH--------------LIKVCMILVFLTGVLG

PF00520 // ENSGT00920000149074_1_Domain_48 (950, 1137)

LCKELIQLFQQ
---RLNYLSDQNNWIEWLIYTTSLVFVSPLFLS--VPADVQWQCGAIAV-YMSWMN-FLL
YLQRFEHFGIYIVMLWEIMRTLFQTTVVF--FFLIL---AFGLSFYI-LLGLQRAYGTPA
LSIMRTFAMMLGDINYQEGFLQPYLDNNLPYPLLSFVCLISFTLLVPILLMNLLIGLAVG
DIAEVQKYASLKRIAMQVELHTNLEKKLPFWFLKKVDQVSVTVHPNRPRYCGIM---GLF
QFCFFFEEPR-QDPPSADN--VLETEVLKQKYRLKDLSTLLEKQHELIRLIIQKMEIVSE
TEEEDTGVSFQDRF-RRQQLERRNSRWTSVLQAVKSKGM-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------N-EKCTALHFAATQGATEIVKLMMSSYAGEESIIDAVD
GNKETLLHRT---ALFDHYELAEYLISMIFN--QATCLERL-LLS-ITAGLHRESHKVEC
VLRKGANVSLKDHLGRNFLHLTVLQPGGLQHLNEKYLQMEHIKNLVVDEDNEGCTPLHYA
CRQGVALSVNNLLSLNVSIYSKSRDKKSPLHF-----AASYGRINTCQRLIRDMKDTRLL
NEGDKKGMTPLHLAAQNGHEKVVQFLLKRGALF---LCDYKGWTALHHAAFGGYTRTMQI
ILDTNVKCT-DRVDEE

PF00023 // ENSGT00920000149074_1_Domain_47 (677, 703)

GNTALHLAAREGHAKAVRLLLDYGAKILFNKAVASFFHEAIHNR
RKDVVSAVILHKR-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------MKRSLRKMLRA-GEKSPH-GVDYQDVENNK
DDSK-----NIESLKVDFED-NEWGFQQSTKNRK-KVS--E-DDENVSPLHHAAAEGQVE
LMK-----MIISDSSCEVLNVMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 236)

YGNTPLHWATEKNQVESVKFLLSKGANPNLRNSSMM
APLHIAVQSM-HNEVVKVLTEHNGTDINLEGE

PF00023 // ENSGT00920000149074_1_Domain_7 (273, 305)

NGNTALITACSKDNSE-ALQMLLQKGAK
LCKSNKWRCFPVHLAAFSGAKKCMELILEF-GEKRGYRRESQINFV--NTGKASPLHFAV
QSGDLEMIKLCLDNGARIDLKEN-GKCMPLHFAATQGATEIVKLMISSYSGSSDIVNAVD
GNHETLLHSR--ASLFDHHELAEYLISVDLSDLNSIISDEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 492)

-RSPLMLATASASWSTVNL
LLSKGAHVDIKDHLGRNFLHLTVQQPYGLKNLHPEFMQMQCIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDL

PF00023 // ENSGT00920000149074_1_Domain_29 (606, 631)

HGMTPLHLAAKNGHDKVVQLLLKKGALF---ISDHNGWTALHHASLGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLSYDADIVLNKQQASFLHVALHNK
RKEVVLTAIRNKRWDECLKVFSHHSP----SNKCPIMEMVEYLPECMKVLLDFCIVPSTG
DKSCRDYHIEYNFKYLRCPLSFTKKYAPVQDVTYEPLPILNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMSLLVVNIKPGMAFNSTG---------IINATSD
-----HSEILDTT---NSY--------------PIKVCMILVFLTSIFGYCKEVAQIFQQ
---KKNYFMDYGNLVEWIIYTTSIVFVLPLFVS--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFEYCGIFIVMLEVILKTLLRSTVVV--VFLLL---AFGLSFYV-LLSAQDAFSSPL
LSIIQTFSMTLGDINYRDAFLEPYLRDELAYPVLSFAQLIAFTMLVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQESTIVYPNRPRYQGTL--SRVL
QYIFYINETR-QEVPNTDT--CLEMEILKQKYRLKDLTSLLEKQHDLIKLIIQKMEIISE
TEDEDNHCSFQDKF-KREQLEQMNSKWNSVLRAVKTKMHNT---------

------------------------------------------------------------
------------------------------MKCSLRKMWRP-GEKKEPQGVVYEDVPDDT
EDF-------KESLKVVFEG-SAYGLQNFN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMM
APLHIAVQGM-NNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFM--NNGKATP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GCHETMLHR---ASLFDHHELADYLISVGAD--INK

ENSGT00920000149074_1_Linker_13_21 (457, 462)

IDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGYDKVVQLLLKKGALF---LS

PF12796 // ENSGT00920000149074_1_Domain_38 (639, 705)

DHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIV

ENSGT00920000149074_1_Linker_38_48 (705, 896)

LNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKIFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMSNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YFYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGMLF--HIF
CFLFCTGEIR-QEIPNADK--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDDDSHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLWRLCQS--REKAAASSAYQGVVCEA
DAASV---ASQDVFKVISDG-SACRLRSFIKKNRSGLT--KVDE

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 201)

LNATPLHHAAEGGQIE
LMQ-----LIIEDSSSEVFNLYCCDLM---HLSLFGTQLYSLW-IWKNCNAPTVSNSHLR
LQLHWLNCRH-MN---VISLEEADAEVRLINSGG---------KKNPFNELGHLKKCGEE
V-RSGRSGGLEWWKKKLLSVKCCCLTVINQ-HYETAQNYDDQYNFRLFGLKKCSSFQYII
FCHTVFFLKFISKFASSFLLSHILIICTHLFCLASEIVA-ATPKEIGKRRGKETLYNVFV
DYSNSFFCQI---NFFLSSEVISYDIYFQHL--FVCLK----HHQLVPGAGRFEVAGIYF
HIYLGANVSLKDHLGRNFLHLTVLQPGGLQHLNEKFLQMEHIKNLVVDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

EGCTPLHYA
CRQGVALSVNNLLSLNVSIYSKS

ENSGT00920000149074_1_Linker_22_23 (564, 565)

R

PF00023 // ENSGT00920000149074_1_Domain_23 (565, 602)

DKKSPLHF-----AASYGRINTCQRLIRDMKDTRLL
NEGDKKGMTPLHLAAQNGHEKVVQFLLKRGALF---LCDYKGWTALHHAAFGGYTRTMQI
ILDTNVKCT-DKVDEEGNTALHLAAKEGHAKAVRLLLDYGAKILLNKAVASFFHEAIHNR
RKDVVSAVILHKRGLLCLNAFFFIHKLSVLIGEYYLYHLCSHFRSSSKLVLDNCIIESSE
EKTSRDFYIEYNFRYLQCPLTLNKKLKESEDIFYEPLAILNAMVRHNRMELLSHPVCKEY
LLMKWMAYGFRAHLMNLGIYSLGLIPLTLLVTHIQPGRSLNGTE---------IYE----
--ARPLEYEVLS-----------------------FLTLCN

PF00520 // ENSGT00920000149074_1_Domain_48 (942, 1138)

IFRMVVEGSCDYFELLIIY
---QLDFFFNFSYIFIFSKMYTSVVYIIMLYKSIAIVEILKDECSAFLLMYLFFLMFLVH
LLPRFENYGIYVVMFWEILRTLIRIAVVF--FFLIL---AFGLSFFVLLGSQ-QTYSTPL
LSVMKTFAMMLGDINYHDAFLDPLLSSELPYPFLSYTVLIIFTLLIPILLMNLLIGLAVG
DIAEVQKYAALKRIAMQVNLHTNLEKKLPFWFLSRVDQESITVYPNRPRYCGFMS---VF
QYCFGCEDST-TDAQSTDT--TLELEVLKQKYRLKDISTLLEKQHDLIKLIIQKMEIVSE
AEDEDSNDLFQHKF-RKRQLEHRNSKWDTVLKAVKSN-------------

------------------------------------------------------------
------------------------------MKRSLKKMLRL-GEKKEPQDVSYEGVEEAA
GDS-------KDSFKVIFER-HACRLQNMIKKRS-RSS--RYDD

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 203)

VNACPLHHAAVEGQVD
LME-----MIINDSCCDVLNVM

ENSGT00920000149074_1_Linker_0_2 (203, 205)

DN

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWATEKNQVESVKFLLSRGANPNLRNNNMM
APLHIAVQCW-HNEVVQVLTEHRSTNINLKGENGNTAVVTACSKD-SE-ALQILFNKGAK
PCIPNK

PF00023 // ENSGT00920000149074_1_Domain_10 (307, 350)

WGCFPIHQAVFSGAKKCMEIVLKF-GEEHGYSRQCHINLV--DNGKHSPLHMAV
QSGDLEMIKMCLDNGAQIDLRES-GKCTALHFAATQGATEIVKLMISSDSSDSDIVNAVD
GNQETLLHSR--ASLFDHHELADYLISMGAD--INSIDS

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATASASWNIVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

HLGRNFLHLTVQQRYGLKNLRPEFMQMQRIKELVMDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

NGCTPLHYA
CRQGVPVSVNNLLHFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLRDITDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALL---LSDH

PF00023 // ENSGT00920000149074_1_Domain_43 (641, 672)

DGWTALHHASIGGYTQTMKV
ILDTNLKCT-DQLDEEGNTALHFAAREGHAKAVTLLLSYDAEIVLNKQDASFLHVAIHNR
RKEVVLTTIRNKRWEECLKTFSHYSQ----SNKCPITEMVEYLPECMKVLLDFCMLHSTE
DKSCRDYHIEYNFRYLQCPLELTKKITPVKDVTYEPLATLNAMVQHNRIELLNHPVCKEY
LCMKWLAYGFRAHIINLGSYCLGLIPMTFLVISIKPGMGFNSTG---------IINETSN
-----HSEMLDTK---NSY--------------SIKVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

ILVFLSSIFGYCKEVAQIFQQ
---KRSYFWDHSNALEWIIYTTSIIFVLPLFTG--IPAHVQWQCGAIAI-FFYWMN-FLL
YLQRFETCGIFIVMLEVIMKTLLRSTVVF--IFLLL---AFGLSFYV-LLSVQDAFSNPV
LSIIQTFSM-MGDVNYRDSFLEPFLRNELAYPILSFIQLICFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVKLHTNLEKKLPLYFLRRVDQQSIVVYPNRPRYQGGL--MCMF
HYMFSVQEAR-QEIPNVDT--SLETEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNRSSFQDKF-KKEQLEQRRSKWNSVLRAVKEKTQCS---------

------------------------------------------------------------
------------------------------MKRNAKKVQLPTGENKEPQGVADEGVENQM
DA------TEEDVFKLKVAEGRYKMLSEFRKNWRTMLRKNPMSSCSFTPVHSASLHNAVF
VLEVSLINGSQSKLCQERLNILDIS

PF00023 // ENSGT00920000149074_1_Domain_2 (206, 237)

GNTPLHWAVEKNQVENVKCLLSRGANPNICNNNLI
APIHLAIQCF-HNDIVKILIEHNTTDVNLIGENGNTPLMLACSKDNSE-ALKLLVENGAK
ICKTNKFGCFPVHIAAFSGSKKCIEMLLKF-GEEQGFSRQYQINFL--NNKNS

PF00023 // ENSGT00920000149074_1_Domain_12 (354, 380)

SPLHFAV
QSGDLEMIKICLANGAQINLEEN-GKCTALHFAATQGAIEIVKLMISSYSGSEDIINTVD
GNNETLLHRV---SLFDHHELAEYLISMGAN--INSIDDEG-RSPLLLATSSASWNIVNL
LLSKGVDVEIKDYFGRNFLHLTVLQPYGLKNLKPEFLQMQCVKNLVMDEDIDGCTPLHYA
CSQGVPLSVNNLLRLDVSICIKSKDNKSPLHF-----AANFGRINTCQRLVREMTDTRLL
NEGDQ

PF00023 // ENSGT00920000149074_1_Domain_30 (606, 631)

NGMTPLHLAAKNGHDKVVKFLLKKGALF---LSDHNGWTALHHASMGGYTQTMKI
ILDTNVKCT-DHVDEEGNTALHYAAREGHAKAVKLLLDYDAEILMNKQSASFLHEAIHNR
RKDVVITTIKSKRWDECMVVFNATSL----TNTCPILEMIEYLPECMNTLLDICIVESLE
ERSCSNFHVEYKFKYLQAPLDFRRKE-DINSTIYGPLTALNAMVKHNRRELLNHPVCREY
LVMKWMAYGFRAHIMNLGFYCLGLIPMTILISNVKPGVAFNSTG---------IIN----
--MTD--NGSEPLDTKNSY--------------LIRVCMILVFLSSVLGFCKEIIQIFQQ
---KINYFLDHSNLIEWTIYTTSIVFVSPLFIS--IPAYLQWQCGAISV-FCFWMN-FLL
YLQRFENYGIYVVMLLEITKTLLKTTFVF--FFLIL---AFGLGFHVLLGFQ-STFKTPV
LSIMQTFSMMLGDINYHESFLEPLLEDRLPYPLLSFLFLVIFTLYIPIVLMNLLIGLAVG
DIAEVQKNASLKRIAMQVKLHTNLEKKLPFWFLNKVDHESIIVYPNRRKNFGFMN---MF
QYWFCARYTK-PETHYADN--TLEVEVLKQKYRLKDLGVLLDKQHELIKLIIQKMEIISE
AEDEDSSFSYQQRF-RNQQLE-KNSKWHTVLKAMKAKTNC----------

------------------------------------------------------------
------------------------------MKCSLKRMLRP-EERKELQGVVYRGVEEDM
DY-------SKDSFKVDIEG-DRYRLEHFMKHRR-KLS--KYED

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

ENISPLHHAAAEGQVE
LMK-----MIIHGSSCEVLNIMDSSGNTPLHWAAEKNQVESVKFLLSQGANPNLRNNNMM
APLHIAVQAS-YNEMTKVLVEHTTTNINLEGENGNTALMSTCAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILKY-GEEHGYKREFHINFV--NHKKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGDLDMIKMCLDNGAHIDMIEN-GKCMALHFAATQGATDIVKLMISSYTGSNDIVNAVD
GNHETLLH-R--ASLFDHHDLADYLISVGAD--INSTDAEG-SSSLILATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLKNLQPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGVPVS

PF12796 // ENSGT00920000149074_1_Domain_22 (549, 631)

VNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKVILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKQHASFLHIALHNKRKEVVLTTIRSDRWDECLQVFSHYSP----SNRCPITEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPLSLTKKVTPTQDVVYEPLTILNVMVQHNRIELLNHPVCKEYLLMKWCAYGFRAHMMNLGSYCLGLIPMTFLVVKIKPGLAFNSTG---------IINETT-----DHLETVDTL---NSF--------------PIKVCMILVFLSSLFGYCKEVVQIFQQ---KRNYFLDYNNALEW------------------------WQCGAIAI-FFYWMN-FLLYLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFSLSFYV-LLNFQDAFSSPLLSLIQTFTMMLGDINYRDAFLEPLLKKELAYPILTFGQLILFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRSAMQVELHTNLEKKLPLWYLRKVDQKSTIVYPNRPRHGR-M--LRFFHYFLWTQETR-QEVPNTDM--CLEMEIL

PF12796 // ENSGT00920000149074_1_Domain_23 (549, 631)

VNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKQHASFLHIALHNK
RKEVVLTTIRSDRWDECLQVFSHYSP----SNRCPITEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLSLTKKVTPTQDVVYEPLTILNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTFLVVKIKPGLAFNSTG---------IINETT-
----DHLETVDTL---NSF--------------PIKVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1149)

ILVFLSSLFGYCKEVVQIFQQ
---KRNYFLDYNNALEW------------------------WQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFSLSFYV-LLNFQDAFSSPL
LSLIQTFTMMLGDINYRDAFLEPLLKKELAYPILTFGQLILFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRSAMQVELHTNLEKKLPLWYLRKVDQKSTIVYPNRPRHGR-M--LRFF
HYFLWTQETR-QEVPNTDM--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDKF-KKERLEQMQSKWNFVLNAVKTKTH-----------

------------------------------------------------------------
------------------------------MKRSLRKMLRP-GEKKEPPGVVYQGVEDDM
DDS-------KDSFKVVFEG-STCGLQNFMKKQK-KLS--KYDDTNASPLHHAAGEGQVE
LMQ-----MIINDSSCEVLNVMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 236)

YGNTPLHWAAEKNQVESVKFLLSKGANPNLRNYNMM
APLHIAVQGL-HNEVMKVLTEHSSTDVNLEGENGNTAAMIACCKDNSE-ALQILFNKGAK
PCKSNKWKCFPVHQAAFSGAKKCMEIILKF-GEEHGYSRESHINFV--NNAKA

PF00023 // ENSGT00920000149074_1_Domain_12 (354, 378)

SPLHMAV
QSGDLEMIKMCLDNGAQLELMEN-AKCTALHFAATQGATEIVKLMISSFSGSSDIVNAVN
GNQETPLHRQ-AASLFDHYELADYLISVGAD--INSTDSEG-RSPLILATTSASWNIVNL
LLSKGARVDIKDHLGRNFLHLTVQQPYGLKNLRPEFMQMQHIKELVMDEDDDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDMSDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASLGGYTQTMKV
ILDTNFKCT-DQLDEE

PF00023 // ENSGT00920000149074_1_Domain_47 (677, 703)

GNTALHFAAKEGHAKAVALLLSYGAD

ENSGT00920000149074_1_Linker_47_48 (703, 953)

IILNKQQASFLHVAIHNK
RKEVVLTTIRNERWGDCFKAFSHYSP----SNKCPTIEMIEYLPECMKVLLDFCIIPSTE
DKSCRDYHIEYNFRYLQCPLEFTKKVTPDQSIKYEPLTALNTMVQHNRIELLNHPVCREY
LLMKWMAYGFRAHLMNLGSYCLGLIPMTLLVVNIKPGMAFNSTG---------IINETSD
-----HSEMLDTK---NSY--------------SIKVCMILVFLSSIFGYCK

PF00520 // ENSGT00920000149074_1_Domain_48 (953, 1137)

EVAQIFQQ
---KKNYFLEFNNVLDWMIYTTSIIFVSPLFVG--IPAHVQWQCGAIAI-FFYWMN-FLM
YLQRFENCGIFIVMLEVIMKTLLRSTVVF--IFLLL---AFGLSFYV-LLSVQDAFSSPP
LSIMQTFSMMLGDINYRDAFLQPFLRNELAYPFLSFVQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLHKVDQKSIMVYPNRPRHTGM-L-LRLY
SHIFCPREAR-QEIPNADT--SLETEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDRF-KKELLEQRNSKWSSVLRAVKAKTHPS---------

------------------------------------------------------------
------------------------------MKCSLRRMLRP-GEKKEAQGVVYWGVEDDV
EG-------SKDSFKVNFEE-NACKLQNFIKSRR-KLN--NCED

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

ENFLSLHHAAAEGQIE
LMK-----IIMHSSSCEVLNVMDDYGNTPMHWAAEKNQVESVKFLLSQGANPNLRNSNMM
APLHIAVQGM-YNEMIKVLVEHSATNINLEGENGNTAVISTCTTDNSE-ALQSLLNKGAK
LCKSNKWGDYAVHQAAFSGAKKCMDLILKY-GEKRGYSRQSHINFV--NHKKVSP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGDLEMIKMCLDNGANIDLVEN-GKCMALHFAATQGATDIVKLMISSYSGNSDIVNATD
GNQETLLH-R--ASLFDHHDLAEYLISVGAD--INST

ENSGT00920000149074_1_Linker_13_21 (458, 462)

DSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAKVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 523)

NLGRNFLHLTVQQPYGLKNLQPEFMQMQQI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLRYNADIVLNKQQASFLHIALHNK
RKEVVLTAIRNKRWDECLQVFTHSSP----INRCPIMEMVEYLPECMKVLLDFCMIPSTE
DKSCRDYHIEYNFKYLQCPLTLTRKLTPVQEVVYEPLSILNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVNIKPGMAFNSTG---------IINETSD
-----HLEVLDTTDCKRYFPFMDNKIKNLTYHNFHN

PF00520 // ENSGT00920000149074_1_Domain_48 (937, 1149)

LCMILVFLSSIFGYCKEVVQIFQQ
---KRNYFLDYNNGLEWIIYTTSIIFVLPLFFN--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLMRSTGVF--IFLLL---AFGLSFYV-LLNLQDAFSSPL
LSLIQTFSMMLGDINYRDAFLEPFLRKELAYPTLSFAQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQKSTTVYPNRPQHGR-I--LRFF
HWFFYTQETK-QEIPNTDT--CLEMEVLKQKYRLKDVTSLLEKQHELIKLIIQKMEIVSE
TEDEDNHCSFQDKF-KKERLEQMNSKWNFVLKAVKTNTQYPNY-------

------------------------------------------------------------
------------------------------MKRNLRRMLRP-AEN-APADVFYQGVEDGV
HDS-------RDSFQVVFEG-GASELHHCMKKQK-KLR--KYDD

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 204)

VDASALHHAAEEGQVE
LME-----MIVSDSPCEVLNVMD

ENSGT00920000149074_1_Linker_0_2 (204, 205)

N

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWAVVKNQAESVKFLLSKGANPNLQNNSMM
APLHLAVQGG-HNEVVKVLTEHSSTDTNLEGENGNTALLIACFQDNSE-AMQMLLNKGAK
ACKANKWGYFPVHQAAFSGAKKCMEIILKY-GDEHGYNRQCHINFV--NN

PF00023 // ENSGT00920000149074_1_Domain_12 (351, 383)

GNVSPLHMAV
QSGDLEMIKMCLDNGAQLELMES-GKCTALHLAATQGATEIVKLMISSYSGSSDIINAVD
GNHETLLHR---ASLFDHHELADYLISVGAD--INSTDS

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATASASWNIVNL
LLSKGARVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

HLGRNFLHLTVQQPYGLNSLRPEFMQMQHIKELVMDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

DGCTPLHYA
CRQGVPISVNNLLNFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDMSDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASLGGYTQTMKV
ILDTNLKSTTDQPDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 708)

EGNTALHLAAREGHAKAVALLLSYDADVVLNK

ENSGT00920000149074_1_Linker_47_48 (708, 940)

HHASFLHFAIHNK
RKEVVLTTIRSKRWEECLKVFNHNSS----CHKYPVMEMVEYLPECMKVXXXXXXXXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXAMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHILNLGSYCLGLLPMTFLVINIKPGLAFNSTG---------IINETSD
-----HSEILDTK---NSY--------------PIKVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

ILVLLSSLFGYFKELAQIFQQ
---KSTYFLDNNNVTEWIIYTTSIIFVSPLFVG--IPAHVQWQCGAVAI-HLYWMN-FLL
YLQRFENCGIFIVMLEVIMKTLLRSTVVF--VFLLV---AFGLSFYV-LLSIQD-FSSPL
LSIMQTFSMMLGDINYRDAFLEPFLRNELAYPVLSFAQLIVFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTNLEKKLPLWFLRQVDQSSIIVYPNRPRCGGRI--LRIF
HFLCRTQDAR-QEIPNVDT--SLEVEILKQKYRLKDLTSLVEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDRY-KKEQLEQRNSRWNSVLKAVKAKTQYPQ--------

------------------------------------------MSISMNKGACA-------
--RGE--------------QLQQVASGVWSMRSSLRKMLRP-GEKKEPPGVVYQGVEDDM
EDS-------KDSFKVVFEE-SACGLQNFLKKRK-RLK--KY

PF12796 // ENSGT00920000149074_1_Domain_0 (163, 236)

DDVNASPLHHAAEEGQVG
LME-----MIVSDSSCEVLNAMDDYGNTPLHWAAEKNQVESIKFLLRKGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 240)

NCNM

PF12796 // ENSGT00920000149074_1_Domain_6 (240, 303)

M
APLHVAVQRL-NNEVMKVLIEHSGTDINLEGENGNTALIIACFTDNSE-AVELLLNKGAK
PCKSNKWGCFPIHQAAFSGAKKCMEIILKF-GEENGYSRVAHINFV--NNRKVSPLHMAV
QSGDLEMIKMCLDNGAQLDLMEK-GKCTALHFAATQGATEIVKLMVSSYSGSQDIINAVD
GNQETLLHR---ASLFDHHELADYLISMGAD--IDSTDSEG-RSPLILATASASWNIVNL
LLSKGARVGIKDHLGRNFLHLTVQQPYGLKNLRPEFLQMQH

PF12796 // ENSGT00920000149074_1_Domain_22 (522, 593)

IKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLDFNVSIHSKNKDKKSPLHF-----AASYGRINTCQRLLQDMSDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASLGGYTQTMKV
ILDTNMKCT-DRLDDEGNTALHFAAREGHAKAVALLLSYDANIILNKQRASFLHVAIHNK
RKEVVLTTIRNKRWEECLMTFSHYSP----SNRCPVMEMVEYLPECMKVLLDFCMMPSTE
DKSSPDYHIEYNFRYLQCPLEFTKKVALVQDVTYEPLSTLNAMVQHNRIELLNHPVCKEY
LLMKWWAYGFRAHVMNLGSYCLGLLPMTFLVISIRPGMAFNSTG---------IINETSD
-----

PF00520 // ENSGT00920000149074_1_Domain_48 (906, 1148)

HSEILDTK---NSY--------------TINVCMILVLLSSIFGYCKEVAQIFQQ
---KRNYFFDNSNALEWIIYTTSIIFVSPLFIS--IPAYVQWQCGAIAI-YLYWMN-FLL
YLQRFENCGIFIVMLEVIMKTLLKSTVVF--VFLLV---AFGLSFYV-LLSIQDAFSSPL
LSIMQTFSMMLGDINYHDAFLDPFLRNELAYPFLSFALLITFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLHKVDQKSITVYPNRPRYSGGLL-RGVL
HYIFCPQETR-QEIPNVDT--SLETEIMKQKYRLKDLSSLLEKQHDLIKLIIQKMEIISE
TEDEDYQSSFQDRF-KKQQLEQRNSKWNSVLRAVKAKTHSP---------

------------------------------------------------------------
------------------------------MKRSLKKMWRP-GEKKEPQGVLYEDVPNDT
DDC-------KESLKVVFEG-SACGLQNFK-NQI-TLN--RCDN

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

VD-ISLHYAAAEGQVK
LME-----KITRDSSFEVLNAMDDYGNTPLHRAVEENQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHLAVQGT-HNEVMKVLLEHRSIDINLEGENGNTAVIIACTKNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEILLRF-GEEHGYNRQLQINFV--NNGKASALHLAV
QNGDLEMIKMCLDNGAQLDLVEK-GRCTALHFAATQGATEIVKLMISSYSGGMDIVNTTN
GSGETMLHR---ASLFDHHELADYLISVGAD--INSIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATTSASWNIVNL
LLSKGAQVNIKD

ENSGT00920000149074_1_Linker_21_22 (493, 548)

NFGRNFLHLTVQHPYGLKNLRPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGGPG

PF12796 // ENSGT00920000149074_1_Domain_22 (548, 631)

SVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDITDTRLL
NEGDLHGMTPLHLAAKNGHEKVVQLLLKKGALF---LSDHNGWTALHHASVGGYTQTMKVILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTTIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLPSTEDKSCRDYYIEYNFKYLQCPLEFTRKTTPTQDITYEPLTALNAMVQNNRIELLNHPVCKEYLLMKWMAYGFRAHMINLGSYCLGLIPLTFLVVNIKPGMAFNSTG---------IINETSD-----HSEILDTT---DSY--------------LIKTCMILVFLSSIFGYCKEVVQIFQQ---KRNYFMDINNIIEWIIYTTGIIFVLPLFVE--IPAHVQWQLNKCVF-FIFVDL-RIV---------DFHCFVGGNLKTLLRSTVVF--VFLLL---AFGLSFYV-LLSLQDAYSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAYPVLSFAQLICFTLFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGILF--HVFFCLFCTGEIR-QEIPNADT--SLEMEI

PF12796 // ENSGT00920000149074_1_Domain_23 (548, 631)

SVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDITDTRLLNEGDLHGMTPLHLAAKNGHEKVVQLLLKKGALF---LSDHNGWTALHHASVGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTTIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLPSTE
DKSCRDYYIEYNFKYLQCPLEFTRKTTPTQDITYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWMAYGFRAHMINLGSYCLGLIPLTFLVVNIKPGMAFNSTG---------IINETSD
-----HSEILDTT---DSY--------------LIKTCMILVFLSSIFGYCKEVVQIFQQ
---KRNYFMDINNIIEWIIYTTGIIFVLPLFVE--IPAHVQWQLNKCVF-FIFVDL-RIV
---------DFHCFVGGNLKTLLRSTVVF--VFLLL---AFGLSFYV-LLSLQDAYSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAYPVLSFAQLICFTLFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGILF--HVF
FCLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHNLEH-------

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKEPQGVVYEDVPDDT
EDC-------KESLKVVFEG-SAYGLQNVN-KQK-KLK--RCDDMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLHEMDDYGNTPLV---EKNQI--------ERANPNLRNFNMM
APLHIAVQGM-NNEVMKVLLEHRTIDVNLEGENGNTAVIVACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFM--NNGKATP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHLAV
QNGDLEMIKMCLDNGAQIDPMEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GCHETMLHR---ASLFDHHELADYLISVGAD--INK

ENSGT00920000149074_1_Linker_13_21 (457, 462)

IDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 537)

NFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKQLVMDEDNDGCTP

PF12796 // ENSGT00920000149074_1_Domain_22 (537, 631)

LHYA
CRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKVILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTIIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTEDKSCRDYYIEYNFKYLQCPLEFAKK-SPTQDVIYEPLTALNV--------------SSMFSLSKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------IINETSD-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ---KRNYFMDMNNVFEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YFYWMN-FLLYLQRFENCGIFIVMLEVILKTLLRSMVVF--VFLLL---AFGLSFYI-LLNLQDPFSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFTQLVSFTIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGMLF--HIFCFLFCNGEIR-QEIPN

PF12796 // ENSGT00920000149074_1_Domain_23 (537, 631)

LHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFAKK-SPTQDVIYEPLTALNV--------------SSMF
SLSKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMNNVFEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YFYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSMVVF--VFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFTQLVSFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGMLF--HIF
CFLFCNGEIR-QEIPNADK--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDSHCSFQDRF-KKEQMEQRNSRWNTVLRAVKEKTHHLEP-------

------------------------------------------------------------
------------------------------MKRGLRRILLP-EERKEVQGVVYRGVGEDM
DC-------SKESFKVDIEG-DMCRLEDFIKNRR-KLS--KH

PF12796 // ENSGT00920000149074_1_Domain_0 (163, 236)

EDENLCPLHHAAAEGQVE
LME-----LIINSSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQGANPNLRNRNMM
SPLHIAVHGM-YNEVVKVLTEHKATNINLEGENGNTALMSTCAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILVY-GEKNGYSRETHINFV--NHKKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGDLDMIKMCLDNGAHIDMMEN-AKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVD
GNQETLLH-R--ASLFDHHDLAEYLISVGAD--INST

ENSGT00920000149074_1_Linker_13_21 (458, 462)

DSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 492)

-RSPLILATASASWNIVNL
LLCKGAKVDIK

ENSGT00920000149074_1_Linker_21_22 (492, 537)

DHLGRNFLHLTVQQPYGLRNLRPEFMQMQHIKELVMDEDNDGCTP

PF12796 // ENSGT00920000149074_1_Domain_22 (537, 631)

LHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHACMGGYTQTMKVILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRNKRWDECLKVFTHDSP----SNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPLSMTKKVAPTQEVIYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTG---------IINGTSS----THEERIDTL---NSF--------------PIKICMILVFLSSIFGYCKEVIQIFQQ---KRNYFLDYNNALEWVIYTTSIIFVLPLFLN--IPAYMQWQCGAIAI-FFYWMN-FLLYLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNFQAAFSTPLLSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQGSTIVYPNRPRHGR-M--LRFFHYFLNMQETR-QEVPN

PF12796 // ENSGT00920000149074_1_Domain_23 (537, 631)

LHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHACMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNK
RKEVVLTTIRNKRWDECLKVFTHDSP----SNRCPIMEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLSMTKKVAPTQEVIYEPLTILNVMVQHNRIELLNHPVCREY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTG---------IINGTSS
----THEERIDTL---NSF--------------PIKIC

PF00520 // ENSGT00920000149074_1_Domain_48 (939, 1149)

MILVFLSSIFGYCKEVIQIFQQ
---KRNYFLDYNNALEWVIYTTSIIFVLPLFLN--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNFQAAFSTPL
LSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQGSTIVYPNRPRHGR-M--LRFF
HYFLNMQETR-QEVPNIDT--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKERLEQMHSKWNFVLNAVKTKTHCSISHPDF---

------------------------------------------MSIFMKKGGRA-------
--RGE--------------QLHQVASGVGSMKRSLRKMWRP-GEKKESQGVVYEDVQDDT
DDC-------KETLKVVFEG-SAYGLQNCN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFV--NNGKASPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INKIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTR

PF12796 // ENSGT00920000149074_1_Domain_25 (599, 667)

LL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMNNVLEWVIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPFLSFAQLICFAIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGLLF--HIF
YFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------------------------------------
---------------VISDG-SACRLRSFIKKNRSGLT--KVDE

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 204)

LNATPLHHAAEGGQIE
LMQ-----LIIDDSSCEVLNVMD

ENSGT00920000149074_1_Linker_0_2 (204, 205)

S

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

SGNTPLHWATKKNQVESVSLLLSRGANPNILNSNMM
APLHMAVQSL-HNEIVKILVQHSSTDVNLEGEAGNTPIIVACYKDNPE-ALTLLIENGGK
ICKPNKTGCMPIHAAAFSGAKTCMEILLKK-GEELGHSAKTHINFT--NNGKCSPLHLAV
QSGDLEMIKMCIEFGAQIDLKQN-EKCTALHFAATQGATEIVKLMMSSYAGEESIIDAVD
G

PF00023 // ENSGT00920000149074_1_Domain_14 (422, 459)

NKETLLHRGLPCLLFDHYELAEYLISMGAN--IDSVD

ENSGT00920000149074_1_Linker_14_21 (459, 460)

I

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATSCASWKIVNL
LLSKGANVSLKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

HLGRNFLHLTVLQPGGLQHLNEKFLQMEHIKNLVVDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

EGCTPLHYA
CRQGVALSVNNLLSLNVSIYSKSRDKKSPLHF-----AASYGRINTCQRLIRDMKDTRLL
NEGDK

PF00023 // ENSGT00920000149074_1_Domain_31 (606, 640)

KGMTPLHLAAQNGHEKVVQFLLKRGALF---LCDYKGWTALHHAAFGGYTRTMQI
ILDTNVKCT-DRVDEEGNTALHLAAKEGHAKAVRLLLDYGAKILLNKAVASFFHEAIHNR
RKDVVSAVILHKRWEEAVLTFSHYSN----ANKCPLLEMVEYLPDSFKLVLDNCIIESSE
EKTSRDFYIEYNFRYLQCPLTLNKKLKDSEDIFYEPLAILNVNISSPKVLTV-YLKITEF
LGWKRMAYGFRAHLMNLGIYSLGLIPLTLLVTHIQPGRPLNGTE---------IYE----
--ARPLEYEVL--ETSDSY--------------FTRVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

CLVLIMSLLGICKEIFQLIQQ
---KLKYLLDYSNLLDWTIYTTSIIFVSSLFIN--TPAHLQWECGAIAV-YLSWMN-FLL
YLQRFENYGIYVVMFWEILRTLIRIAVVF--FFLIL---AFGLSFFVLLGSQQQTYSTPL
LSVMKTFAMMLGDINYHDAFLDPLLSSELPYPFLSYTVLIIFTLLIPILLMNLLIGLAVG
DIAEVQKYAALKRIAMQVNLHTNLEKKLPFWFLSRVDQESITVYPNRPRYCGFMF--VLF
RYCFGCEDST-TDAQSTDT--TLELEVLKQKYRLKDLSTLLEKQHDLIKLIIQKMEIVSE
AEDEDSNDLFQHKF-RKRQLEHKNSKWDTVLKAVKTNVPNPST-------

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKESQGVVYEDVQDDT
DDC-------KETLKVVFEG-SAYGLQNCN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFV--NNGKASPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INKIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTR

PF12796 // ENSGT00920000149074_1_Domain_26 (599, 667)

LL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMNNVLEWVIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPFLSFAQLICFAIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGLLF--HIF
YFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLRKMLRP-GE-KEPQDVVYQGVEDDM
D-------ESKDSFKVVFEG

PF12796 // ENSGT00920000149074_1_Domain_0 (141, 236)

-NAHRLQNFIKNRR-KLS--KYDDTNASPLHHAAAEGQVE
LMK-----TIISGSSCAVLNVMDDYGNTPLHWATEKNQVESVKFLLSQGANPNLRNGNMM
APLHIAAQGM-YNEIIKVLTEHRSTNINLEGENGNTALLTTCAKDNSE-ALQILVCVLII
-----------------FSALYCLTI---------LANRQSHINFV--NNKKVSPLHLAV
QSGDLEMIKMCLDNGAHIELVEN-GKCMA

PF12796 // ENSGT00920000149074_1_Domain_13 (390, 486)

LHFAATQGATEIVKLMISSYSGDSNIVNALD
GNCETLLH-R--ASLFDHHELAEYLISAGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKG

ENSGT00920000149074_1_Linker_13_22 (486, 537)

TKREQAKALEPV-LDLVRPTPLRV---VLFPLPMQHIKELVMDEDNDGCTP

PF12796 // ENSGT00920000149074_1_Domain_22 (537, 630)

LHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGT--------------------------MKVILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLSHDAEIILNKQQASFLHIALHNKRKEVVLTTIRSKRWDECLQVFTHHSP----SNRCPTMEMVEYLPECMKVLLDFCMIPSTEDKSCRDYHIEYNFRYLQCPLELTKHTTPIQGVIYEPLSVLNVMVQHNRIELLNHPVCKEYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVNVKPGMAFNSTG---------IINETSD-----HLEILDST---NSY--------------AIQVCMILVFLSSIFGYCKEVVQIFQQ---KRNYFLDYNNALEWLIYTTSIIFVLPLFVN--VPANVQWQCGAIAI-YFYWMN-FLFQFELFLC--------------------------PLN---IFNI-KFV-LKYEDDAFSSPLLSIIQTFSMMLGDINYRDAFLEPFLRNELAYPFLSFAQLIVFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNRPRGGK-I--LRLFHYLFGSHEIR-QEISNT

PF12796 // ENSGT00920000149074_1_Domain_23 (537, 630)

LHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGT--------------------------MKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLSHDAEIILNKQQASFLHIALHNK
RKEVVLTTIRSKRWDECLQVFTHHSP----SNRCPTMEMVEYLPECMKVLLDFCMIPSTE
DKSCRDYHIEYNFRYLQCPLELTKHTTPIQGVIYEPLSVLNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVNVKPGMAFNSTG---------IINETSD
-----HLEILDST---NSY--------------AIQVCMILVFLSSIFGYCKEVVQIFQQ
---KRNYFLDYNNALEWLIYTTSIIFVLPLFVN--VPANVQWQCGAIAI-YFYWMN-FLF
QFELFLC--------------------------PLN---IFNI-KFV-LKYEDDAFSSPL
LSIIQTFSMMLGDINYRDAFLEPFLRNELAYPFLSFAQLIVFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNRPRGGK-I--LRLF
HYLFGSHEIR-QEISNTDT--CLEIEMLKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDKF-KKERLELMSSRWNSVLRAVKTKTQCLEPRP-----

------------------------------------------------------------
------------------------------MKRNLRKMLRS-GEKKEPQGVVYQGVEDDM
DDSQ-------DSFKXXXXX-XXXXXXNFLKKKQ-LWS--RYDD

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 204)

ISASPLHYAAEEGQVQ
LME-----MILNDSPCEVLNMMD

ENSGT00920000149074_1_Linker_0_2 (204, 205)

N

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWAAGKNQVESVRFLLSKGANPNLRN

ENSGT00920000149074_1_Linker_2_3 (237, 238)

R

PF00023 // ENSGT00920000149074_1_Domain_3 (238, 272)

SMM
APLHIAVQNF-NNEVMKVLTEHSNTNLNLEGENGNTAVIIACSKDNSE-ALQILLNKGAK
PCKANKWGGYPVHQAAFSGAKKCMEIILKY-GEDHGYKRHSHINFV--NNGRSSPLHMAV
QSGDLEMIKMCLDNGAQLDLMEX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXX-XXXXXXXXXXXXXXXXX

PF00023 // ENSGT00920000149074_1_Domain_20 (449, 459)

GAD--INATD

ENSGT00920000149074_1_Linker_20_21 (459, 460)

S

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATASASWNTVNL
LLSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 708)

EGNTALHFAAREGHAKAVSLLLSYDADIVLNK

ENSGT00920000149074_1_Linker_47_48 (708, 941)

QKASFLCA--HNK
RKXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXAVLDLCMMPSTD
DKSCKDYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX--XXXX-XXXXX-X---XXXXXXXXXXXXX---------XXXXXXX
-----XXXXXXXX---XXX-----------XXXXXXXXXX

PF00520 // ENSGT00920000149074_1_Domain_48 (941, 1138)

XXXXXXXXXXXXXXXXXXXX
XXXKRNYFSDINNAVEWVIYTTSIVFVLPLFTG--IPGHVQWQCGAIAI-FCYWMN-FLL
YLRRFENCGIFIVMLDVIMKTLLRSTVVF--IFLLL---AFGLSFYV-LLNLQDAFSSPL
LSIVQTFSMMLGDISYRDAFLEPFLRNELTYPFLSFAQLIIFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTGLEKKLPLWFLRKVDQKSVIVYPNRPRYGGGL--FCIF
HYLFHTYEAR-QEMPNTDT--VLETEMLKQKYRLKDLTSLLERQHELIKLIIQKMEIISE
TEDEDSHSSFQDKF-KREQLEQRNSKWNCVLNAVKAKAHKLKS-------

------------------------------------------------------------
------------------------------MKRSLRKMLRT-GE-KEPQAVVYHGVD-S-
-------MSDSKDFKVVFEG-NKCRLQHFVKNRW-

PF12796 // ENSGT00920000149074_1_Domain_0 (156, 236)

KLN--KYKEANVSPLHHAAAEGQLE
LMK-----MIISGSSCEVLNVMDSYGNTPLHWAAENNQVESVKFLLTQGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 243)

NSSMM
AP

PF12796 // ENSGT00920000149074_1_Domain_6 (243, 329)

LHLAVQGM-YNEITKVLIEHSSTNINLEGENGNTAVMITCAKDNSE-SLEILLKKGAK
LCKSNKWGDFPVHQAAFSGAKKCMELILKF-GEENGYSKQSHINFL--NNKQASPLHLAV
QSGNLEMIKMCLDNGAHIEQIEN-GKCMALHFAATQGATEIVKLMISSYSGSSDIVNAFD
GNHETLLH-R--ASLFDHHELADYLISVGAD--INITDSEG-RSPLVLATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHFTVQQPYGLKSLRPEFMQMQEI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KALVMDEDNDGCTPLHYA
CKQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTIKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLNYDADIVLNKQRASFLHIALHNK
RKEVVLTTIRNKRWDECLKVFTHCSP----SNRCPIMEMIEYLPECMKILLDFCMIPSTE
DKSCPDYHIEYSFRYLQCPLELTQKLTPGQEVQYEPLSILNVMVQHSRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVINIKPGTAFNSTG---------IINE

PF00520 // ENSGT00920000149074_1_Domain_48 (898, 1149)

THD
-----HLEILDTT---NSY--------------PIKVCMILVFLSSIFGYCKEVVQIFQQ
---KKNYFLDYNNVLEWIIYTKSIIFVLPLFVN--IPAYVQWQCGAIAI-FFYWMN-FLM
YLQRFENCGIFIVMLEVIFKTLLRSAGVF--IFLLL---AFGLSFYV-LLNEQDPFSSPL
LSLIQTFTMMLGDVNYRVAYLEPFLKNELAYPILSFAQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIVVYPNRPRYGR-M--LRLF
RYFFGIQEAR-QEIPNTDT--CLELEMLKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHTSFQDRF-KKEQLEQMNSKWNFVLRAFKAKPHCPTSHSDFQ--

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKASQGVVYEDVQDDT
DDC-------KETLKVVFEG-SAYGLQNYN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMM
APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFV--NNGKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INK

ENSGT00920000149074_1_Linker_13_21 (457, 462)

IDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRL

PF12796 // ENSGT00920000149074_1_Domain_47 (674, 729)

DEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTI

ENSGT00920000149074_1_Linker_47_48 (729, 896)

IRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMNNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPFLSFAQLICFAIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGLLF--HIF
YFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLRRVLRP-EERKEVQGVVYRGVGEDM
DC-------SKESFKVDIEG-DMCRLEAFIKNRR-KLS--KY

PF12796 // ENSGT00920000149074_1_Domain_0 (163, 236)

EDENLCLLHHAAAEGQVE
LMQ-----LIINGSSCEALNVMDDYGNTPLHWAAEKNQVESVKFLLSQGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 243)

NRNMM
AP

PF12796 // ENSGT00920000149074_1_Domain_6 (243, 332)

LHIAVQGM-YNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKRCMELILAY-GEKTGYSREAHINFV--NHKKASPLHLAV
QSGDLDMIKMCLDSGAHIDMMEN-AKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVD
GNQETLLH-R--ASLFDHHDLADYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFLQMQH

PF12796 // ENSGT00920000149074_1_Domain_22 (522, 593)

IKELVMDEDNDGCTPLHYA
CRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNK
RKEVVLTTIRSKRWDECLQVFTHDSP----SNRCPIMEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLSMTKKVTPTQDVIYEPLTILNVMVQHNRIELLNHPVCREY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTG---------IINETIS
----THEERINTL---NSF--------------PLKIC

PF00520 // ENSGT00920000149074_1_Domain_48 (939, 1149)

MILVFLSSIFGYCKEVVQIFQQ
---KRNYFLDYNNALEWVIYTTSMIFVLPLFLD--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNFQDAFSTPL
LSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPFWYLRKVDQRSTIVYPNRPRHGR-M--LRFF
HYFLSMQETR-QEAPNIDT--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKERLEQMHSKWNFVLNAVKTKTHCSISHPDI---

------------------------------------------------------------
------------------------------MKCSLRRMLRP-EERKEIQGVAYCGVKEDR
DC-------FKDSFKVDMEG-DTYRLEDFIKNRR-KLS--KFE

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DENISPLHHAAAEGQIE
LMK-----MIIHGSSCEVLNIMDSCGNTPLHWAAEKNQVESVKFLLSQGANPNLRNSTLM
APLHIAVQSS-YNEMIKVLTEHNTTNINLEGENGNTAVMSTCAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILKY-GEKHGCSRGTHINFV--NHKKVSP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGDLDMIQMCLDNGAHVDMIEN-GKCMALHFAATQGATDIVKLMISSYTGSRDIVNAVD
GNQETLLH-R--ASLFDHHDLADYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLKNLRPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTR

PF12796 // ENSGT00920000149074_1_Domain_27 (599, 666)

LL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLNYNAEILLNKQHASFLHIALHNK
RKEVVLTTIRSKRWDECFQVFSHYSP----SNRCPIMEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLALTKKLTPTQDVRYEPLAILNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTFLVVKIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETT-
----NHLETVDTL---NSF--------------PIKICMILVFLSSLFGYCKEVVQIFQQ
---KRNYFLDYNNALEWVIYTTSIIFVLPLFLN--IPAYMQWECGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLSFQDAFSTPL
LSLIQTFSMMLGDINYRDAFLEPFLKKELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHAALKRIAMQVELHTNLEKKLPLWFLRKVDQQYTVVYPNRPRHGR-M--LRFF
HYFLCTQETR-QEAPNTDM--CLEIEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDKF-KKERLEQMQSKWNFVLNAVKNKPHCPIIHPGLE--

------------------------------------------------------------
------------------------------------------------------------
------------------DG-SACRLRSFIKKNRSGLT--KVDELNATPLHHAAEGGQIE
LMQ-----LIIDDSSCEVLNVMDSS

PF00023 // ENSGT00920000149074_1_Domain_2 (206, 236)

GNTPLHWATKKNQVESVRLLLSRGANPNILNSNMM
APLHMAVQSL-HNEIVKVLVQHSSTDVNLEGEAGNTPIIVACYKDNPE-ALTLLVENGGK
ICKPNKTGCMPIHAAAFSGAKACLEILLKK-GEELGHSAKTHINFT--NNGK

PF00023 // ENSGT00920000149074_1_Domain_12 (353, 381)

CSPLHLAV
QSGDLEMIKMCIEFGAQIDLKQN-EKCTALHFAATQGATEIVKLMMSSYAGEESIIDAVD
GNKETLLHRT---ALFDHYELAEYLISMGAN--IDSVDIEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 492)

-RSPLLLATSCASWKIVNL
LLSKGANVSLKDHLGRNFLHLTVLQPGGLQHLNEKYLQMEHIKNLVVDEDNEGCTPLHYA
CRQGVALSVNNLLSLNVSIYSKSRDKKSPLHF-----AASYGRINTCQRLIRDMKDTRLL
NEGDKK

PF00023 // ENSGT00920000149074_1_Domain_37 (607, 631)

GMTPLHLAAQNGHEKVVQFLLKRGALF---LCDYKGWTALHHAAFGGYTRTMQI
ILDTNVKCT-DRVDEEGNTALHLAAREGHAKAVRLLLDYGAKILFNKAVASFFHEAIHNR
RKDVVSAVILHKRWEEAVVTFSHSSS----ANKCPLLEMVEYLPDSFKLVLDNCIIESSE
EKTSRDFYIEYNFRYLQCPLTLNKKVKDGEDIFYEPLTTLNAMVRHNRMELLSHPVCKEY
LLMKWMAYGFRAHLMNLGIYSLGLIPLTLLVTHIQPGRPLNGTE---------LYE----
--ARPLEYEEHKKDMLDSY--------------FTRVCMCLVLIMSLL

PF00520 // ENSGT00920000149074_1_Domain_48 (949, 1137)

GICKEIFQLIQQ
---KLKYLLDYSNLLDWTIYTTSIIFVSSLFIN--TPAHLQWECGAIAV-YLSWMN-FLL
YLQRFENYGIYVVMFWEILRTLIRIAVVF--FFLIL---AFGLSFFVLLGSQ-QTYSTPL
LSVMKTFAMMLGDINYHDAFLDPLLSSELPYPFLSYTVLIIFTLLIPILLMNLLIGLAVG
DIAEVQKYAALKRIAMQVNLHTNLEKKLPFWFLSRVDQESITVYPNRPRYCGFMV-RCVF
QYCFGCEDST-TYAQSPDT--TLELEVLKQKYRLKDISTLLEKQHDLIKLIIQKMEIVSE
AEDEDSNDLFQHKF-RKRQLEHKNSKWDTVLKAVKT--------------

------------------------------------------------------------
------------------------------MRRSLRKMLSP-GKQEEPQGAVYQGVENDM
DDS-------KDSLKVVFEG-STCRLKNLLKKRK-KLS--KYDDMNASPLHHAAAEGHVE
LME-----MIINDSSFEVLNVMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 236)

YGNTPLHWAAEKNQVESVKFLLSKGANPNLRNSSMM
APLHIAVQSL-HNEVMKVLTEHSSTDINLEGENGNTAVIIACSKDNSE-ALRILLNKGAQ
PCKSNKWGCFPIHQAAFSGAKKCMEIILKFEGEEHGYSRQSHINFV--NNGKA

PF00023 // ENSGT00920000149074_1_Domain_12 (354, 378)

SPLHMAV
QSGDLEMIKMCLDNGAQLELMEN-GKCTPLHFAATQGATEIVKLMLSSYSGSSDIVNAVD
GNHETLLHR---ASLFDHHELAGYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGARVDIKDHLGRNFLHLTVQQPHGLKNLQPEFMQMQHIKQLVMDEDDDGCTPLHYA
CRHGIPVSVNNLLDFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDMSDTRLL
NEGDL

PF00023 // ENSGT00920000149074_1_Domain_32 (606, 631)

HGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASLGGYTQTMKV
ILDTNLKCT-DQLDEEGNTALHFAAREGHAKAVALLLSYDADVVLNKQQASFLHVAIHNK
RKEVVLTTIKNKRWEECLKVFSHYSP----SNKCPVMEMVEYLPECMKVLLDCCIIPSTG
DKSCKDYHIEYNFTYLQCPLEFTKKLIPAQDVTYEPLTTLNVMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHVMNLGSYCIGLLPMTFLVTSIKPGMAFNSTG---------IINETHD
-----HSEILDTK---NSY--------------FIKVCMILVFLSSIFGYCKEVVQIFQQ
---KRNYILDNANAVEWIIYTTSIIFVSPLFVG--IPASVQWQCGAIAI-YFYWMN-FLL
YLQRFENCGIFIVMLEVIVKTLLRSTVVF--VFLLL---AFGLSFYV-LLSLQDAFSTPL
LSIIQTFSMMLGDINYRDAFLEPFLRNELAYPVLSFIQIIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLRRVDQKSIIVYPNRPRCSGL---LRIF
HFLFHTKETR-QEIPNVDT--SLEIEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDRF-KKEQLEQRNSKWNSVLKAVKTKTH-----------

------------------------------------------------------------
------------------------------MRRSLRKMLRP-VSLSQLQSPLYVGFLTFI
SQTKS----AFHVPSVVFEG-NKCGLQNFVKKHK-RLK--KYDDVNASPLHHAAEEGQVE
LME-----MIVNESSCEVLNVMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 236)

YGNTPLHWAAGKNQVESVKFLLRKGANPNLRNCSMM
APLHVAVQGG-YNDVMKVLIEHSSTDVNLEGENGNTALIITCFTDNSE-AMQLLLNKGAK
PCKSNKWGCFPIHQAAFSGAKKCMEIILKF-GEEHGYSRLCHINFV--NSGKASPLHMAV
QSGDLDMIKMCLDNGAQLDLLEK-GKCTALHFAATQGATEIVKLMVSSYSGSSDIVNEVD
GN

PF00023 // ENSGT00920000149074_1_Domain_17 (423, 458)

HETLLHR---ASLFDHHELADYLISVGAD--IDITDSEG-RSPLLLATASASWNTVNL
LLSKGARVDIKDNLGRNFLHLTVQQPYGLKNLHPEFLQMQHIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLNFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHSGWTALHHASLGGYTQTMKV
ILDTNLKCT-DRLDEE

PF00023 // ENSGT00920000149074_1_Domain_47 (677, 703)

GNTALHFAAREGHAKAVSLLLSYDADVVLNKQQASFLHVAIHNK
RKEVVLTTIRNKRWGECFKVFNHCSP----TNRCPVIELVEYLPECMKVLLDFCVMPSTE
DKSSQDYHIEYNFTYLQCPLEFTKKGTPVQDVVYEPLLTLNAMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHVLNLGSYCLGLFPMTFLVVSIRPGMAFNSTG---------IINETSD
-----HSEILDTK---NSY--------------AINFCMILVLLSSILGYCKEVAQIFQQ
---KRNYFLDKDNAAEWIIYTTSIIFVSPLFIR--IPAYVQWQCGAVAI-FLYWMN-FLL
YLQRFEKCGIFIVMLEVIMKTLLKSTIVF--VFLLV---AFGLCFYV-LLNFQDAFSSPF
LSIMQTFSMMLGDINYHDAFLEPYLKDELEYPLLSFVHLITFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLHKVDQKSIIVYPNRPRYSRGIL-RGVF
HYIFCPHETR-QEIPNVDT--SLETEIMKQKYRLKDLGSLLEKQHELIKLIIQKMEIISE
TEDEDYHSSFQDRF-KKQQLEQRNSKWNCVLRAVKAKTHSP---------

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKEPQGVVYEDVP---
DDC-------KETLKVVFEG-SACGSQNCN-KQE-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLRRGANPNLRNFNMM
APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEELGYSRQLHINFV--NNGKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHLAV
QNGDLEMIKMCLDNGAQLDPEEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INK

ENSGT00920000149074_1_Linker_13_21 (457, 462)

IDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 537)

NFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTP

PF12796 // ENSGT00920000149074_1_Domain_22 (537, 631)

LHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDVSDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKVILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTIIRSKRWDECLKVFSHNSP----CNKCPITEMIEYLPECMKVLLDFCMLHSTEDKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVVYEPLTALNAMVQNNRIELLNHPVCKEYLLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------IINETSD-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ---KMNYFMDMSNVLEWIIYTTGIIFVLPLFIE--IPAHLQWQCGAIAV-YLYWMN-FLLYLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLISFSIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGILF--HIFCILFCTGEIR-QEIPN

PF12796 // ENSGT00920000149074_1_Domain_23 (537, 631)

LHYACRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDVSDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKVFSHNSP----CNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVVYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KMNYFMDMSNVLEWIIYTTGIIFVLPLFIE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLISFSIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGILF--HIF
CILFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLRKLLRS-GE-TEPQGAVYQGVDDS-
-------MPDSKDFKVVFEG-NECRLQH

PF12796 // ENSGT00920000149074_1_Domain_0 (149, 236)

IIKNRW-KLN--KYEEENVSALHHAAGEGQLE
LMK-----MIISGSSCEVLNLMDNYGNTPMHWAAENNQVESVKFLLIHGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 240)

NNNM

PF12796 // ENSGT00920000149074_1_Domain_6 (240, 303)

M
APLHIAVQGM-HNEMAKVLIEHSSTNINLEGENGNTAVMITCTKDNSE-ILEILLKKGAK
LCKSNKWGDFPVHQAAFSGAKKCMELILKF-GEEDGYSRQCHINFV--NNKQVSPLHLAV
QSGNLEMIKMCLDNGAHIEKIEN-GKCMALHFAATQGATEIVKLMLSSYSGNSNIINAVD
GNHETLLH-R--ASLFDHHELADYLISVGAD--INITDSEG-RTPLVLATASASWNIVNL
LLSKGARVDIKDYLGRNFLHFTVQQPYGLKNLRPEFMQMQEIKALVMDEDNDGCTP

PF12796 // ENSGT00920000149074_1_Domain_22 (537, 631)

LHYA
CKQGVHVSVNNLLGFNVSIYSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---L-----------------------------------------------------------------------------------------------------------------------------------ILLDFCMIPSTEDKSCQDYHIEYNFRYLQCPLQFTRKLPAEQEVHYEPLSTLNVMVQHNRIELLNHPVCKEYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVINIKPGTAFNSTG---------IINETHN-----Q---TDTT---NSY--------------PIKVCMILVFLSSIFGYCKEVIQIFQQ---KRNYFLDYNNALEWVIYTKSIIFVLPLFVS--IPAYVQWQCGAIAI-FLYWMN-FLMYLQRFENWGIFIVMLEVIFRTLLRSTGVF--IFLLL---AFGLSFYV-LLNAQDAFRSPLLSLVQTFTMMLGDVNYRDTYLQPFLKNELTYPVLSFVQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLPIWFLRRVDQKSTIVYPNRPRYGP-V--LRLFHYFFGVQETR-QELPN

PF12796 // ENSGT00920000149074_1_Domain_23 (537, 631)

LHYACKQGVHVSVNNLLGFNVSIYSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---L-----------------------
------------------------------------------------------------
------------------------------------------------ILLDFCMIPSTE
DKSCQDYHIEYNFRYLQCPLQFTRKLPAEQEVHYEPLSTLNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVINIKPGTAFNS

PF00520 // ENSGT00920000149074_1_Domain_48 (883, 1149)

TG---------IINETHN
-----Q---TDTT---NSY--------------PIKVCMILVFLSSIFGYCKEVIQIFQQ
---KRNYFLDYNNALEWVIYTKSIIFVLPLFVS--IPAYVQWQCGAIAI-FLYWMN-FLM
YLQRFENWGIFIVMLEVIFRTLLRSTGVF--IFLLL---AFGLSFYV-LLNAQDAFRSPL
LSLVQTFTMMLGDVNYRDTYLQPFLKNELTYPVLSFVQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPIWFLRRVDQKSTIVYPNRPRYGP-V--LRLF
HYFFGVQETR-QELPNTDT--CLELEMLKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDRF-KKERLEQMNSKWNFVLRAVKTKPHISHLDL-----

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKESQGVVYEDVQDDT
DDC-------KETLKVVFEG-SAYGLQNYN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFV--NNGKASPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSADIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INKIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 523)

NFGRNFLHLTVQQPYGLKNLRPEFMQMQQI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KELVMDEDNDGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMNNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPFLSFAQLICFAIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGLLF--HIF
YFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLRKILRP-GEKKEPQDVVYQGVQDDM
DDS-------KESLKVVFEG-SACTSQNFIQKQK-RLN--GR

PF12796 // ENSGT00920000149074_1_Domain_0 (163, 236)

YDTNASPLHHAAAEGQVE
LMN-----MIINDSSCEVLNVMDDYGNTPLHWAAEKNQVESVKFLLSKGANPNLRNSAMM
AALHVAVQAM-HNEVVKVLTEHSSTNVDLEGESGNTAVLMACSKDNSE-ALQILFNKGAK
SCKPNKWGCFPVHQAAFSGAKKCMEIILKY-GEEHGYSREFHINFV--NNGKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHMAV
QSGDLEMIKMCLDNGAHIDLMEN-GRCMALHFAATQGATEIVKLMISSYSGSTNIVNAVD
GNQETLLHR---ASLFDHHELADYLISVGAD--INSIDCEG-RSPLILATASASWNIVNL
LLSKGARVDIKDHYGRNFLHLTVQQPYGLKNLRPEFMQMQHIKELVMDEDNDGCTPLHYA
CREGVPVSVNNLLDFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHAAMGGYTQTMKV
ILDTNLKCT-DRLDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 703)

DGNTALHFAAREGQAKAVGLLLSRDAD

ENSGT00920000149074_1_Linker_47_48 (703, 959)

IVLNKQQASFLHLAFHNK
RKEVVLTAIRSKRWDECLKVFSHCSP----SNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSRLDYHIEYNFKYLQCPSAFTKKVRPTQDAIYEPLTALNAMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMSLLVVNIKPGMAFNSTG---------IINETSD
-----HSEIKL----------------------------------------------D

PF00520 // ENSGT00920000149074_1_Domain_48 (959, 1149)

TT
---KSNYFRDINNLTEWIIYTASIIFVLPLFAN--IPAFMQWQCGAIAV-FFYWIN-FLL
YLQRFETCGIFIVMLEVILKTLFRSTVVF--VFLFV---AFGLSFYV-LLNMQDTFSTPW
LAIIQTFSMMLGDISYRDAFLEPFLRNELTYPFLSFVHLIIFTLLVPIVLVNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTGLEKKLPLWFLRKVDQKSTIVYPNKPRSTGR-L-FNLF
CYLFFNQEKR-QEMPNADT--SLEMEILKQKYRLKDLTVLLEKQHELIKLIIQKMEIISE
AEDEDNHCSFQDKF-KKEQLEQRNSKWNCVLRAVKAKTHQPH--------

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKASQGVVYEDVQDDT
DDC-------KETLKVVFEG-SAYGLQNYN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFV--NNGKASPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INKIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRL

PF12796 // ENSGT00920000149074_1_Domain_47 (674, 729)

DEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTI

ENSGT00920000149074_1_Linker_47_48 (729, 897)

IRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------IIN

PF00520 // ENSGT00920000149074_1_Domain_48 (897, 1149)

ETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMNNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPFLSFAQLICFAIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGLLF--HIF
YFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------------------------------------
-------------IPEQDDP-SFSVLEDFMKNRR-KLS--KYED

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

ESISPLHHAAAEGQVE
LMK-----MIIHGSSCEVLNIMDSSGNTPLHWAAEKNQVESVKFLLSQGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 239)

NNN

PF12796 // ENSGT00920000149074_1_Domain_6 (239, 303)

MM
APLHIAVQSS-YNEMTKVLVEHNTTNINLEGENGNTASMSACAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILKH-GEEHGYKRESHINFV--NHKKASPLHLAV
QSGDLDMIKMCLDNGAHIDMIEN-GKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVD
GNHETLLH-R--ASLFDHHDLADYLISMGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLKHLRPEFMQMQH

PF12796 // ENSGT00920000149074_1_Domain_22 (522, 594)

IKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDMSDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKQHASFLHIALHNK
RKEVVLTTIRSKRWDECLRVFSHYSP----SNRCPIVEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLSLTKKVTPTQDVVYEPLTILNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIKPGMAFNSTG---------IIN

PF00520 // ENSGT00920000149074_1_Domain_48 (897, 1149)

ETS-
----DHLETVDTL---NSF--------------PIKMCMILVFLSSIFGYCKEVVQIFQQ
---KKNYFLDYNNALEWVIYTTSIVFVLPLFLN--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFSLSFYV-LLNFQDAFSSPL
LSLIQTFSMMLGDINYRDAFLEPFLKKELTYPILTFGQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQKSTIVYPNRPRHGR-M--LRFF
HYFLCTQETR-QEVQNTDM--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDKF-KKERLEQMQSKWNFVLNAVKTKTH-----------

------------------------------------------------------------
------------------------------MKRGLRRILRP-EERKEVQGVVYRGVGEDM
DC-------SKESFKVDIEG-DMCRLEDFIKNRR-KLS--KY

PF12796 // ENSGT00920000149074_1_Domain_0 (163, 236)

EDENLCPLHHAAAEGQVE
LME-----LIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQGANPNLRNRNMM
SPLHIAVHGM-YNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILVY-GEKNGYSRESHINFV--NHKKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGDLDMIKMCLDNGAHIDMMEN-AKCMALHFAATQGATDIVKLMISSYNGSSDIVNAVD
GNQETLLH-R--ASLFDHHDLAEYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLCKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFMQMQHIKELVMDEDNDGCTP

PF12796 // ENSGT00920000149074_1_Domain_22 (537, 631)

LHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKVILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRSKRWDECLQVFTHDSP----SNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPLSMTKKVAPTQDVIYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTG---------IINGTSS----THEERIDTL---NSF--------------PIKICMILVFLSSIFGYCKEVIQIFQQ---KRNYFLDYNNALEWVIYTTSIIFVLPLFLN--IPAYMQWQCGAIAI-FFYWMN-FLLYLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNFQDAFSTPLLSLIQTFSMMLGDINYRDAFLEPLFRDELAYPILTFGQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQRSTIVYPNRPRHGR-M--LRFFHYFLNMQETR-QEVPN

PF12796 // ENSGT00920000149074_1_Domain_23 (537, 631)

LHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNK
RKEVVLTTIRSKRWDECLQVFTHDSP----SNRCPIMEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLSMTKKVAPTQDVIYEPLTILNVMVQHNRIELLNHPVCREY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTG---------IINGTSS
----THEERIDTL---NSF--------------PIKIC

PF00520 // ENSGT00920000149074_1_Domain_48 (939, 1149)

MILVFLSSIFGYCKEVIQIFQQ
---KRNYFLDYNNALEWVIYTTSIIFVLPLFLN--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNFQDAFSTPL
LSLIQTFSMMLGDINYRDAFLEPLFRDELAYPILTFGQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQRSTIVYPNRPRHGR-M--LRFF
HYFLNMQETR-QEVPNIDT--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKERLEQMHSKWNFVLNAVKTKTHCSISHPDF---

------------------------------------------------------------
------------------------------MKRALLKMFQP--REKAA-CGFYQGVVCEA
DAASL---ASQDVFKMISDG-SACRLRSFIKKNRSGLS--KLDELNATPLHHAAGAGQIE
LME-----MIIDDSSNEALNVMDSF

PF00023 // ENSGT00920000149074_1_Domain_2 (206, 236)

GNTPLHWAAKRNQAESVKLLLSRGANPNILNSSMM
APLHLAVQSL-HNEIVKIFLYCGSTDVNLEGETGNTPIIVACYKENPE-ALTLLLENGGK
LCKSNKTGCMPVHAAAFSGAKACLEIILKK-GEELGHSAESHINFT--NNGK

PF00023 // ENSGT00920000149074_1_Domain_12 (353, 381)

CSPLHLAV
QSGDLEMIKMCIEYGAQIDLKQN-EKCTALHFAATQGATEIVKLMMSSYAGDESIIDAVD
GNKETLLHRT---ALFDHYELAEYLISMGAN--IDSLDIEG-RSPLLLATTCASWKIVNL
LLSKGANVFLKDQLGRNFLHLTVLQPGGLQHLDGKFLQMKYIKDLVVEEDDEGCTPLHYA
CRQGVPFSVNSLLDLNVSVYSKSRDKKSPLHF-----AASYGRINTCQQLLRGMNDTRLL
NEGDKKGMTPLHLAAQNGHEKVVQFLLKKGALF---LCDYKGWTALHHAAFGGYTRTMQI
ILDTNVKST-DRVDEE

PF00023 // ENSGT00920000149074_1_Domain_47 (677, 703)

GNTALHLAAKEGHAKAVRLLLDCGAK

ENSGT00920000149074_1_Linker_47_48 (703, 947)

IILNKASASFFHEAIHNR
RKDVVSAVILNKRWEEAVTTFSHSST----SNKCPLLEMIEYIPESLKLVLDNCMIESSE
EKSSQDFYIEYNFRYLQCPLILNKKIKAGEEIVYEPLTTLNAMVRHNRMELLNHPVCKEY
LLMKWMAYGFRAHIMNLGIYSLGLVPLTLLITRIQTPTKQDHL-----------------
----TNGTEKEGEGSKDSY--------------FIRVCMCLVFVMS

PF00520 // ENSGT00920000149074_1_Domain_48 (947, 1137)

LFGICKEIFQLFQQ
---KLKYLLDCSNLLDWTIYTSSIMFVSSLFVN--IPAHLQWECGAIAV-YLSWMN-FLL
YLQRFENYGIYIVMFWEILRTLLRIAVVF--FFLIL---AFGLSFFVLLCSQ-HHYKTPL
LSVMQTFAMMLGDINYHEAFLDPLLSNNLPYPFLSYAVLIIFTLLIPILLMNLLIGLAVG
DIAEVQKYAALKRIAMQVNLHTNLEKKLPYWFLSRVDQESITVYPNRPRYCGFMS---VF
NYCFGYEDSV-TDAQSADT--TLELEILKQKYRLKDMSTLLEKQHELIKLIIQKMEIVSE
AGDEDSNDLFQHKF-RKQQLEHMNSKWDTVLKAVKSKCP-----------

------------------------------------------------------------
------------------------------MKRSLRKMLRP-GEKKEPQSVVYQGVEDDM
DESKE-------SIKXXXXX-XXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXX
XXX-----XXXXXXXXXXLNEMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWAAEKNQIESVKFLLSRGANPNLRNNNMM
APLHIAVQAT-HNEVMKVLTEHSSTNINLEGE

PF00023 // ENSGT00920000149074_1_Domain_8 (273, 306)

SGNTAVMIACSKDNSE-ALQILXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X--XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXN-GXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX
XXXXXXXXXX-XASLFDHHELADYLISVXXXXXXXXXXXXX---XXXXXXXXXXXXXXXX
XXXXXARVDIKDHFGRNFLHLTVQQPYGLRNLRPEFLQMKHIKLV-MD-ED

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

DGCTPLHYA
CRQEVPVSVNNLLGFNVSINSKSKDKKSPLHF-----AASYGRINTCQRLLKDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LXXXXXXXALHHASMGGYTQTMKV
-IDTNMKCT-DRLDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 708)

EGNTALHFAAREGHAKAVALLLSYDAEIVLNKQQASFLHVALHNK
RKEVVLTAIRNKRWDDCLKVFSHYSS----SNKCPIMEMVEYLPECMKVLLDFCMVHSTE
D-SCEDYHXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXVMVQHNRIELLNHPVCKEY
LLMKWMAYGFRAHMMNLGSYCLGLIPMTLLVVSITPGMAFNSTG---------IINETRG
-----HTEILDTT---NSY--------------PIKICMILVFLSSIFGCFKEVAQIFQQ
---KRNYFLDVNNAIEWIIYIASMIFVLPLFIN--IPGDVQWQCGAMAI-YFYWMN-FLL
YLQRICI-----------MKTMHRFVF----IFMLLSFPSFEISLYTMAFPIHDAFSSPL
LSIIQTFSMMLGDVNYRDSFLEPFLRDELAYPFLSFSQLTVFTIFVPIALMNLL---GLD
DIAEVQHAS---LRAMQVELHTSLEKKLPLWFLRKVDQKSIVVYPNRPRHGGRL--LRIF
CYLFCVKEAK-QEMPHTDT--SLEMEILKQKYRLKDVTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQLEQRNSKWNSVLKAVKAKTHCSY--------

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKEPQGVVYEDVPDDT
EDF-------KESLKVVFEG-SAYGLQNFN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMM
APLHIAVQGM-NNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSE-ALQILLKKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFM--NNGKATPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GCHETM

PF12796 // ENSGT00920000149074_1_Domain_21 (427, 505)

LHR---ASLFDHHELADYLISVGAD--INKIDSEG-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDH

PF12796 // ENSGT00920000149074_1_Domain_44 (641, 705)

NGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIV

ENSGT00920000149074_1_Linker_44_48 (705, 896)

LNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKIFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDISNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YFYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGMLF--HIF
CFLFCTGEIR-QEIPNADK--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDDDSHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MRRSLRKMLSP-GKQEEPQGAVYRGVENHT
DDS-------MDALKVVFDG-SACRYKNFMKK

PF12796 // ENSGT00920000149074_1_Domain_0 (153, 236)

RK-KLN--KYDNMNTSPLHHAAEEGQVE
LME-----MIISDSSFEVLNVMDDYGNTPLHWAAEKNQVESVKFLLSKGANPNLRNSNMM
APLHIAVQGL-HNEVIKVLTEHNSTDINLEGE

PF00023 // ENSGT00920000149074_1_Domain_9 (273, 305)

NGNTAVIIACLKDNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGAKKCMEIILKF-GEEHGYSRQSHINFV--NNGKSSPLHMAV
QSGDLEMIKMCLDNGAHLELMEN-GKCTPLHFAATQGATEIVKLMISSYSGSSDIVNAVD
GNQETLLHR---ASLFDHHELADYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGARVDIKDNLGRNFLHLTVQQPYGLKNLRPEFMQMQHIKNLVMDEDDDGCTPLHYA
CRHGIPVSVNNLLDFNVSLRSKSKDKKSPLHF-----AASYGRINTCQRLLQDMSDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTA

PF12796 // ENSGT00920000149074_1_Domain_47 (646, 727)

LHHASLGGYTQTMKV
ILDTNLKCT-DLLDEEGNTALHFAAREGHAKAVALLLSYDAAIVLNKQQASFLHVAIHNK
RKEVVLTTIKNKRWEECLEVFSHYSP----SNGCPVLEMVEYLPECMKVLLDCCIIPSTR
DKSCEDYHIEYNFTYLQCPLEFTKKVTPTQDVTYEPLTTLNAMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHIMNLGSYCLGLLPMTFLVVSIKPGMAFNSTG---------IINETTD
-----HSEILDTK---NSY--------------SIKVCMILVFLSSIFGYCKEVTQIFQQ
---KRNYMLDQANAVEWIIYTTSIIFVLPLFIG--IPAYVQWQCGAIAI-YFYWMN-FLL
YLQRFENCGIFIVMLEVIMKTLLRSTVVF--VFLLL---AFGLSFYV-LLSLQDAFSSPL
LSIIQTFTMMLGDINYRDAFLEPFLRNELAYPVLSFTQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIVVYPNRPRCTGL---LRIF
HFIFYTKEAR-QEIPNVDT--SLEIEISKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDRF-KKEQLEQRNSRWNSVLKAVKAKTHC----------

------------------------------------------------------------
------------------------------MKSSLRKMLRS-GEK-QPQGGVYEGVEEDM
EDSK-------DSFKXXXXX-XXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXX
XXX-----XXXXXXXXXXLNVMDN

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLYWATDKNQVKSIQFLLSRGANPNIRNYNMM
APLHIAVQRG-YNELVKVLVEHGSTNINLEGENGNTAVMFACSKDNSE-ALQFLLNKGAK
PCIQNKWGCFPIHQAAFSGAKKCMEIILKF-GEDHGHSRNNHINFV--NN

PF00023 // ENSGT00920000149074_1_Domain_12 (351, 383)

GKHSPLHMAV
QSGDLEMIKMCLDNGAQIELMEX-XXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXX
XXXXXXXXXX-XXSLFDHHELAEYLISVXXXXXXXXXXXXX---XXXXXXXXXXXXXXXX
XXXXXAHVDIKDFLGRNFLHLTVQQSHGLKNLQPEFMQMKHIKELVMDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

NGCTPLHYA
CRQGVPVSVNNLLHFNVSINSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDMRLL
NEGDLHGMTPLHLAAKNGHDKVVHLLLKKGALF---LSDHYGWTALHHASMGGYTQTMKV
ILNTNLKCT-DRLDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 708)

EGNTALHFAAREGHAKAVALLLSCGADIVLNK

ENSGT00920000149074_1_Linker_47_48 (708, 1021)

QDACVLHVAIHNK
RKDVVLTRIRSQRWEECFKVFSHRS-----SIKCLVMEMVGYLPECXXVLLDLCMLHSTE
DKSCRDYHIEYNFKY-QCPLEFTQ-----------------AMVQHNRIELLNHPVCKEY
LCMKWLAYGFKAHIVNLGSYCLGLMPMTFLVVNIKPGMGFNSTG---------IINGTSD
-----HSEILDTQ---NSY--------------PIKVCMILVFLSSILGYCKEVSQIFQQ
XXXXXXXXXXXXXXXXXXX----XXXXXXXXXX--XXXXXXQQCAAA-------LY-MTL

PF00520 // ENSGT00920000149074_1_Domain_48 (1021, 1138)

YLQRFENCGIFIVMLQVIMKTLLRSTVVF--IFLLV---AFGLSFYI-LLSIQDAFSHPL
LSIIQTFSMMLGDINYRDSFLEPFLRDELAYPLLSFIQLITFTLFVPIVLMNLLIGLAVG
NIAEVQKHASLKRIAMQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX-
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDSHSSFQDKF-KKEQLEQRNSKWNCLLKAVKSQGSPG---------

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKEPQGVVYEDVP---
DDC-------KETLKVVFEG-SACGSQNCN-KQE-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMM
APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTALIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEFGYSRQLHINFV--NNGKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHLAV
QNGDLEMIKMCLDNGAQIDPEEK-GRCTAIHFAATQGATEIVKLMISSYSGSMDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INK

ENSGT00920000149074_1_Linker_13_21 (457, 462)

IDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQGISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDYNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRL

PF12796 // ENSGT00920000149074_1_Domain_47 (674, 729)

DEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTI

ENSGT00920000149074_1_Linker_47_48 (729, 954)

IRSKRWDECLKVFSHNSP----CNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVVYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------IINET--
----------------------------------------------------K

PF00520 // ENSGT00920000149074_1_Domain_48 (954, 1149)

AGQIFQQ
---KVNYFMDTSNILEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLISFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGILF--HIF
RFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLKRMWRP-GEKKEPQGVLYEDVPDDA
DDC-------KEPLKVVFEG-SACGLQDF------ILN--RCDNVD

PF12796 // ENSGT00920000149074_1_Domain_0 (167, 236)

-ISLHYAAAEGQVE
LME-----KITRDSSFEVLNAMDDYGNTPLHRAVEENQIESVKFLLSRGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NFNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHIAVQGM-HNEVMKVLLEHRSTNVNLEGENGNTAVIIACIKNNSE-ALEILLTKGAK
PCKSNKWGCFPIHQAAFSGSKECMEILLRF-GEELGYSRQLQINFV--NNGKASALHLAV
QNGDLEIIKMCLDNGAQIDLAEK-GRCTALHFAATQGATEIVKLMISSYSGGMDIVNTTN
GSGETMLHR---ASLFDHHELADYLISVGAD--VNSIDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVNVKDNFGRNFLHLTVQHPYGLKNLRPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDITDTRLL
NEGDLHGMTPLHLAAKNGHEKVVQLLLKKGALF---LS

PF12796 // ENSGT00920000149074_1_Domain_39 (639, 705)

DHNGWTALHHASVGGYTQTMKA
ILDTNLKCT-DSLDDDGNTALHFAAREGHAKAVALLLSHNADIV

ENSGT00920000149074_1_Linker_39_48 (705, 897)

LNKQQASFLHLALHNK
RKEVVLTAIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLPSTE
DKSCRDYYIEYNFRYLQCPLEFTRKTAPTQDITYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWMAYGFRAHMINLGSYCLGLIPMTFLVVNIKPGMAFNSTG---------IIN

PF00520 // ENSGT00920000149074_1_Domain_48 (897, 1149)

ETSD
-----HSEILDTT---DSY--------------LIKTCMILVFLSSIFGYCKEVVQILQQ
---KRNYFMDINNIIEWIIYTTGIIFVLPLFIE--IPAYVQWQCGAIAI-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--VFLLL---AFGLSFYV-LLNLQDAYSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAYPVLSFAQLIFFTLFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLHKVDQKSTIVYPNKPRSGGILF--HIF
CFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLSFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEH-------

------------------------------------------------------------
------------------------------MRRSLRKMLRP-GEKKEPRDFVCLGVEDHK
DNSND----FKTKLNVVFEG-NKCGLQNFVKKQK-RFK--KYDDVNASPLHHAAEEGQVE
LME-----MIVNESSCEVLNVMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 236)

YGNTPLHWAAGKNQVESVKFLLRKGANPNLRNCSMM
APLHVAVQGG-YNDVMKVLIEHSSTDVNLEGENGNTALIITCFTDNSE-AMQLLLNKGAK
PCKSNKWGCFPIHQAAFSGAKKCMEIILKF-GEEHGYSRLSHINFV--NSGKA

PF00023 // ENSGT00920000149074_1_Domain_12 (354, 380)

SPLHMAV
QSGDLDMIKMCLDNGAQLDLLEK-GKCTALHFAATQGATEIVKLMVSSYSGNSDIVNEVD
GNHETLLHR---ASLFDHHELADYLISVGAD--IDITDSEG-RSPLLLATASASWNTVNL
LLSKGARVDIKDNLGRNFLHLTVQQPYGLKNLHPEFLQMQHIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLNFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDL

PF00023 // ENSGT00920000149074_1_Domain_33 (606, 631)

HGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASLGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVSLLLSYDADVVLNKQQASFLHVAIHNK
RKEVVLTTIRSKRWGECFKVFNHCSP----TNRCPVIELVEYLPECMKVLLDFCVMPSTE
DKSSQDYHIEYNFTYLQCPLEFTKKGTPVPDIVYEPLLTLNAMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHVLNLGSYCLGLFPMTFLVVSIRPGMAFNSTG---------IINETSD
-----HSEILDTK---NSF--------------AINFCMILVLLSSILGYCK

PF00520 // ENSGT00920000149074_1_Domain_48 (953, 1137)

EVAQIFQQ
QPQKRNYFLDKDNAAEWIIYTTSIIFVSPLFIR--IPAYVQWQCGAVAI-FLYWMN-FLL
YLQRFEKCGIFIVMLEVIMKTLLKSTIVF--VFLLV---AFGLCFYV-LLNIQDAFSSPF
LSIIQTFSMMLGDINYHDAFLEPYLKNELEYPLLSFVHLIIFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLHKVDQKSIIVYPNRPRYSRGIL-RGVF
HYIFCPHETR-QEIPNVDT--SLETEIMKQKYRLKDLSSLLEKQHELIKLIIQKMEIISE
TEDEDYHSSFQDRF-KKQQLEQRNSKWNCVLRAVKAKTHSP---------

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKEPQGVVYEDVP---
DDC-------KETLKVVFEG-SACGSQNCN-KQE-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLNEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMM
APLHLAVQGT-HNEVMKVLLEHRTIDINLEGENGNTALIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEFGYSRQLHINFV--NNGKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHLAV
QNGDLEMIKMCLDNGAQIDPEEK-GRCTAIHFAATQGATEIVKLMISSYSGSMDIVNTTD
GSHETMLHR---ASLFDHHELADYLISVGAD--INK

ENSGT00920000149074_1_Linker_13_21 (457, 462)

IDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPDSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQGISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDYNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRL

PF12796 // ENSGT00920000149074_1_Domain_47 (674, 729)

DEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNK
RKEVVLTI

ENSGT00920000149074_1_Linker_47_48 (729, 896)

IRSKRWDECLKVFSHNSP----CNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVVYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KMNYFMDTSNILEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLISFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNKPRCGGILF--HIF
RFLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKCSRRRILRP-EEQKELQGVVYRGVKVNM
DS-------SKESFKVGFEG-DTYRLEDFIKNRR-KLS--KY

PF12796 // ENSGT00920000149074_1_Domain_0 (163, 236)

EDENISPLHHAAAEGQVE
LMK-----MIIHSSSCEVLNIMDNYGNTPLHWAVEKNQVESVKFLLSQGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 241)

NSNMM

PF12796 // ENSGT00920000149074_1_Domain_6 (241, 303)

APLHIAVQGT-YNEMTKVLVEHNDTNINLEGENGNTAVMSASAKDNSE-ALQTLLDKGAK
ICKSNKWGDYPVHQAAFSGAKRCMELILKY-GEKHGYRRELHINFV--NHKKVSPLHLAV
QSGDLEMIKMCLDNGAHIDMIEN-GKCMALHFAATQGATDIVKLMISSYTGSTDIVNAVD
GNQETLLH-R--ASLFDHHDLADYLISVGAD--INSTDSEG-RSPLILATASASWNTVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLKNLQPEFMQMQH

PF12796 // ENSGT00920000149074_1_Domain_22 (522, 593)

IKELVMDEDNDGCTPLHYA
CKQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AACYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTLTMKV
ILNTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLNYNAEILLNKQQASFLHIALHNK
RKEVVLTTIRSKRWDECLQVFTHLSP----SNRCPIMEMIEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLTLTKKLTPTQDVTYEPLTMLNVMVQHNRVELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVNIKPGMAFNSTG---------IISE

PF00520 // ENSGT00920000149074_1_Domain_48 (898, 1149)

TS-
----DQLEVVDTT---DSF--------------PIKICMILVFLSSIFGYCKEVVQIFQQ
---KRNYFLDYNNALEWIIYTTSIVFVLPLFLN--IPAHVQWQCGAISI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNLQDAFSSPL
LSLIQTFSMMLGDINYRDSFLEPFLRKKLAYPILSFGQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPFWYLRKVDQKSTIVYPNRPRHGR-M--LRFF
HYFLCTQEAR-QEIPNTDT--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDKF-KKERLEQMHSKWNFVLNAVKTKTQYPNY-------

------------------------------------------------------------
------------------------------------------------------------
-----------WSPAVVFEG-NKCGLQNFVKKHK-RLK--KY

PF12796 // ENSGT00920000149074_1_Domain_0 (163, 236)

DDVNASPLHHAAEEGQVE
LME-----MIVNESSCEVLNVMDDYGNTPLHWAAGKNQVESVKFLLLKGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 243)

NCSMM
AP

PF12796 // ENSGT00920000149074_1_Domain_6 (243, 329)

LHVAVQGG-YNDVMKVLIEHSSTDVNLEGENGNTALIITCFTDNSE-AMQLLLNKGAK
PCKSNKWGCFPIHQAAFSGAKKCMEIILKF-GEEHGYSRLSHINFV--NSGKASPLHMAV
QSGDLDMIKMCLDNGAQLDLLEK-GKCTALHFAATQGATEIVKLMVSSYSGSSDIVNEVD
GNHETLLHR---ASLFDHHELADYLISVGAD--IDITDSEG-RSPLLLATASASWNTVNL
LLSKGARVDIKDNLGRNFLHLTVQQPYGLKNLHPEFLQMQHI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLNFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHSGWTALHHASLGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVSLLLSYDADVVLNKQQASFLH------
RKEVVLTTIRNKRWGECFKVFNHCSP----TNRCPVIELVEYLPECMKVSSKNKIPL--V
FKNCYLLQIEYNFTYLQCPLEFTKKGTPVQDVVYEPLLTLNAMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHVLNLGSYCLGLFPMTFLVVSIRPGMAFNSTG---------IINETSA
-----HSEILDTK---NSY--------------AIN

PF00520 // ENSGT00920000149074_1_Domain_48 (937, 1148)

FCMILVLLSSILGYCKEVAQIFQQ
---KRNYFLDKDNAAEWIIYTTSIIFVSPLFIR--IPAYVQWQCGAVAI-FLYWMN-FLL
YLQRFEKCGIFIVMLEVIMKTLLKSTIVF--VFLLV---AFGLCFYV-LLNFQDAFSSPF
LSIMQTFSMMLGDINYHDAFLEPYLKDELEYPLLSFVHLITFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLHKVDQKSIIVYPNRPRYSRGIL-RGVF
HYIFCPHETR-QEIPNVDT--SLETEIMKQKYRLKDLGSLLEKQHELIKLIIQKMEIISE
TEDEDYHSSFQDRF-KKQQLEQRNSKWNCVLRAVKAKTHSP---------

------------------------------------------------------------
------------------------------MKRSLRKMLRT-GE-KEPQAVVYHGVD-S-
-------MSDSKDFKVVFEG-NKCRLQHFVKNRW-

PF12796 // ENSGT00920000149074_1_Domain_0 (156, 236)

KLN--KYKEANVSPLHHAAAEGQLE
LMK-----MIISGSSCEVLNVMDSYGNTPLHWAAENNQVESVKFLLTQGANPNLRNSSMM
APLHLAVQGM-YNEITKVLIEHSSTNINLEGENGNTAVMITCAKDNSE-SLEILLKKGAK
LCKSNKWGDFPVHQAAFSGAKKCMELILKF-GEENGYSKQSHINFL--NNKQASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGNLEMIKMCLDNGAHIEQIEN-GKCMALHFAATQGATEIVKLMISSYSGSSDIVNAFD
GNHETLLH-R--ASLFDHHELADYLISVGAD--INITDSEG-RSPLVLATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHFTVQQPYGLKSLRPEFMQMQEI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KALVMDEDNDGCTPLHYA
CKQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTIKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLNYDADIVLNKQRASFLHIALHNK
RKEVVLTTIRNKRWDECLKVFTHCSP----SNRCPIMEMIEYLPECMKILLDFCMIPSTE
DKSCPDYHIEYSFRYLQCPLELTQKLTPGQEVQYEPLSILNVMVQHSRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVINIKPGTAFNSTG---------IINE

PF00520 // ENSGT00920000149074_1_Domain_48 (898, 1149)

THD
-----HLEILDTT---NSY--------------PIKVCMILVFLSSIFGYCKEVVQIFQQ
---KKNYFLDYNNVLEWIIYTKSIIFVLPLFVN--IPAYVQWQCGAIAI-FFYWMN-FLM
YLQRFENCGIFIVMLEVIFKTLLRSAGVF--IFLLL---AFGLSFYV-LLNEQDPFSSPL
LSLIQTFTMMLGDVNYRVAYLEPFLKNELAYPILSFAQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIVVYPNRPRYGS-M--LRLF
RYFFGIQEAR-QEIPNTDT--CLELEMLKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHTSFQDRF-KKEQLEQMNSKWNFVLRAFKAKPHCPTSHSDFQ--

------------------------------------------------------------
------------------------------MKRSLRKMLHA-GEKKPPPVVGYHGVENGV
DDCK-----NFE---VVFGG-DACGFEKFIK-RR-KLS--K-QD

PF00023 // ENSGT00920000149074_1_Domain_1 (165, 177)

ENDYPLHHAAAE

ENSGT00920000149074_1_Linker_1_2 (177, 205)

GXXX
XXX-----XXXXXXXXXXVNMMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWATEKNKGESIKFLLSKGANPNVQNNNMM
APLHVAVQNM-YNEVVKILTDYSGTDIDLEGENGNTAVITACSKDNSE-ALEILLKKGAR
ICKANKWKCFPVHHAAFSGAKKCLELLLEY-GEKLGYRREYQINFV--NT

PF00023 // ENSGT00920000149074_1_Domain_12 (351, 383)

RNASPLHFAV
QSGDLEMIKLCLDNGARIDQKEN-AKCTALHFAASQGATEIVKLMISSYSGTSDIVNAVD
GNHETLLH-R--ASLFDHYELAEYLVSVGAD--VNITDA

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLMSATASASWNVVNL
LLSKGAHVHIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

HHGRNFLHLTVQQPYGLKNLQPEFMQMQHIKELVMDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

DGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQGISDTRLL
NEGDLNGMTPLHLAAKNGHDKVVQLLLKKGALF---INDHNGWTALHHASLGGYTQTMKV
ILDTNLKCT-DRLDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 710)

EGNTALHFAAKGSHAKAVALLLKYDAHIVLNKQQ

ENSGT00920000149074_1_Linker_47_48 (710, 940)

ASFLHVALHNK
RKEVVLMTIRNKRWDECLKVFSHYSP----TNRCPIMEMVEYLPECMKVLLDFCIIPSTG
DKSCRDYHIEYNFKYLHCPLALTKEKAPVQDVTYEPLPILNVMVQHNRIELLNHPVCKEY
LLMKWFAYGFRAHMMNLGSYCLGLIPMTMLVVNIQPGMAFNSTG---------IINETSD
-----HSEILDTT---NSY--------------PIKVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

ILVFLTSIFGYCKEVAQIFQQ
---KKNYFMDYGNAVEWIIYTTSMIFVLPLFVS--IPAYAQWQCGAIAI-FLYWMN-FLM
YLQRFEYCGIFIVMLEVILKTLLRSTVVL--LFLLL---AFGLSFYV-LLSTQDAFKTPL
LSIIQTFSMTLGDINYRDAFLEPYLRSELTYPSLSFAQLIAFTMLVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPVWFLHKVDQESTIVYPNRPRCEGMF--ACIL
QYIFCTKETR-QEVPNTDK--CLEIEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDED---------------------------------------------

------------------------------------------------------------
------------------------------MRRSLRKMLSA-GKQEEPPGAVYQGVENDM
VDS-------KDSLKVVLEG-STCRFKNQMKKRK-KLS--KYDD

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 204)

MNTSPLHHAAEEGHVE
LME-----MIINDSSFEVLNVMD

ENSGT00920000149074_1_Linker_0_2 (204, 205)

D

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWAAEKNQVESVKFLLSKGANPNLRNSNMM
APLHLAVQNL-HNEVMKVLTEHSSTDINLEGENGNTAVIIACSKDNSE-ALQILLNKGAE
PCKSNKWGCFPIHQAAFSGAKKCMEIILKY-GEEHGYNRQSHINFV--NSRKASPLHMAV
QSGDLEMIKMCLDNGAQLEMMEN-

PF00023 // ENSGT00920000149074_1_Domain_13 (385, 418)

GKCTPLHFAATQGATEIVKLMISSYSGSRDIVNAVD
GNQETLLHR---ASLFDHHELADYLISVGAD--INSTDS

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLILATASASWNIVNL
LLSKGARVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

QLGRNFLHLTVQQPHGLKNLRPEFMQMQHIKKLVMDEDD

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

DGCTPLHYA
CRHGIPVSVNNLLDFNVSIRSKS

ENSGT00920000149074_1_Linker_22_23 (564, 565)

K

PF00023 // ENSGT00920000149074_1_Domain_23 (565, 602)

DKKSPLHF-----AASYGRINTCQRLLQDMSDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASLGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLSYDADIVLNKQQASFLHVAIHNK
RKEVVLTTIKNKRWEECLKVFSHYSS----SNKCPVMEMVEYLPECMKVLLDCCIIPSTG
DKSCRDYHIEYNFTYLQCPLEFTKKLTPAQDVTYEPLTTLNVMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHVMNLGSYCIGLLPMTFLVVSIKPGMAFNSTG---------IINETSD
-----HSEILDTK---NSY--------------SIKVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

ILVFLSSIFGYCKEVVQIFQQ
---KRNYILDHANAVEWVIYTTSIVFVSPLFIG--IPASVQWQCGAIAI-YFYWMN-FLL
YLQRFENCGIFIVMLEVIMKTLLRSTVVF--VFLLL---AFGLSFYV-LLSLQDAFSSPL
LSIIQTFSMMLGDINYRDAFLEPFLRNELAYPVLSFIQIIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNRPRCTGL---LRIF
HFFFCTKETR-QEIPNADT--SLEIEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIVSE
TEDEDNHSSFQDRF-KKEWLEQRNSKWNSVLKAVKTKTHSPSH-------

------------------------------------------------------------
--------------------------------------------------SAYQGVVCEA
DAASV---ASQDVFKVISDG-SACRLRSFIKKNRSGLT--KVDELNATPLHHAAEGGQIE
LMQ-----LIIDDSSCEALNVMDSS

PF00023 // ENSGT00920000149074_1_Domain_2 (206, 236)

GNTPLHWATKKNQVESVRLLLSRGANPNILNSNMM
APLHMAVQSL-HNEIVKILVQHSSTDVNLEGEAGNTPIIVACYKDNPE-ALTLLIENGGK
ICKANKTGCMPIHAAAFSGAKTCLEILLKK-GEELGHSAKTHINFT--NNGK

PF00023 // ENSGT00920000149074_1_Domain_12 (353, 381)

CSPLHLAV
QSGDLEMIKMCIEFGAQIDLKQN-EKCTALHFAATQGATEIVKLMMSSYAGEESIIDAVD
GNKETLLHRT---ALFDHYELAEYLISMGAN--IDSVDIEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 492)

-RSPLLLATSCASWKIVNL
LLSKGANVSLKDHLGRNFLHLTVLQPGGLQHLNEKYLQMEHIKNLVVDEDNEGCTPLHYA
CRQGVALSVNNLLSLNVSIYSKSRDKKSPLHF-----AASYGRINTCQRLIRDMKDTRLL
NEGDKKGMTPLHLAAQNGHEKVVQFLLKRGALF---LCDYKGWTALHHAAFGGYTRTMQI
ILDTNVKCT-DRVDEE

PF00023 // ENSGT00920000149074_1_Domain_47 (677, 703)

GNTALHLAAREGHAKAVRLLLDYGAK

ENSGT00920000149074_1_Linker_47_48 (703, 949)

ILFNKAVASFFHEAIHNR
RKDVVSAVILHKRWEEAVVTFSHYST----ANKCPLLEMVEYLPDSFKLVLDNCIIESSE
EKTSRDFYIEYNFRYLQCPLTLNRKLKDGEDIFYEPLTTLNAMVRHNRMELLSHPVCKEY
LLMKWMAYGFRAHLMNLGIYSLGLIPLTLLVTHIQPGRPLNGTE---------LYE----
--DFH--------SKKDSY--------------FTRVCMCLVLIMSLL

PF00520 // ENSGT00920000149074_1_Domain_48 (949, 1137)

GICKEIFQLIQQ
---KLKYLLDYSNLLDWTIYTTSIIFVSSLFIN--TPAHLQWECGAIAV-YLSWMN-FLL
YLQRFENYGIYVVMFWEILRTLIRIAVVF--FFLIL---AFGLSFFVLLGSQQQTYSTPL
LSVMKTFAMMLGDINYHDAFLDPLLSSELPYPFLSYTVLIIFTLLIPILLMNLLIGLAVG
DIAEVQKYAALKRIAMQVNLHTNLEKKLPFWFLSRVDQESITVYPNRPRYCGFMS---VF
QYCFGCEDST-TYAQSPDT--TLELEVLKQKYRLKDISTLLEKQHDLIKLIIQKMEIVSE
AEDEDSNDLFQHKF-RKRQLEHKNSKWDTVLKAVKTNVPNPSTEKNNSFF

------------------------------------------------------------
------------------------------MKRSLRKMWRP-GEKKEPQGVVYEDVPDDT
EDF-------KESLKVVFEG-SAYGLQNFN-KQK-KLK--RCD

PF12796 // ENSGT00920000149074_1_Domain_0 (164, 236)

DMDTFFLHCAAAEGQIE
LME-----KITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMM
APLHIAVQGM-NNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFM--NNGKATP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GCHETMLHR---ASLFDHHELADYLISVGAD--INK

ENSGT00920000149074_1_Linker_13_21 (457, 462)

IDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYA
CRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LS

PF12796 // ENSGT00920000149074_1_Domain_40 (639, 705)

DHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIV

ENSGT00920000149074_1_Linker_40_48 (705, 896)

LNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKIFSHNSP----GNKCPITEMIEYLPECMKVNS---------
-LKQNSSWVYYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYCKEAGQIFQQ
---KRNYFMDMSNVLEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YFYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--IFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGMLF--HIF
CFLFCTGEIR-QEIPNADK--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDDDSHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------MKRSLRKMLRP-GEKKAAQGAVYQGVQDHM
DDS-------KESLKVVFEG-SSCALQNFIKKQK-KLR--KY

PF12796 // ENSGT00920000149074_1_Domain_0 (163, 236)

GDMNASPLHHAAGEGQVE
LMQ-----MILNESSCEALNVMDDCGNTPLHWAAEKNQVESVKFLLSRGANPNLQ

ENSGT00920000149074_1_Linker_0_6 (236, 240)

NSNM

PF12796 // ENSGT00920000149074_1_Domain_6 (240, 304)

M
APLHIAVQGM-HNNVMKVLTEHSSTNINLEGENGNTAVMIACTKDNNE-ALQILFNKGAK
PCISNKWGCFPVHQAAFSGAKKCMEIILKF-GEEHGYSRESHINFV--NNGKASPLHMAV
QSGDLEMIKMCLDNGAHIDLMET-GRCTALHFAATQGATEIVKLMISSYSGGTDIVNAVD
GHHETLLHR---TSLFDHHELADYLISVGAD--INSIDSEG-RSPLLLATASASWNIVNL
LLSKGARVDIKDHFGRNFLHLTVQQPYGLRNLCPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLLGMTPLHLAAKNGHDKVVQLLLKRGALF---LS

PF12796 // ENSGT00920000149074_1_Domain_41 (639, 705)

DHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLSHDADIV

ENSGT00920000149074_1_Linker_41_48 (705, 896)

LNKQQASFLHLALHNK
RKDVVLTAIRSQRWDDCLKVFSHCSP----SNKCPIMEMVEYLPECMKVLLDFCMIPSTE
DKSCRDYHIEYNFKYLQCPLEFTKQAAPTQDVVYEPLLALNAMVQHNRIELLHHPVCKEY
LLMKWLAYGFRAHMLNLGSYCLGLIPMTLLVVNIKPGMAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETTD
-----HSEILDTT---SSY--------------PIKVCMILVFLSSILGYCKEVAQIFQQ
---ERNYFWDHNNIVEWIIYTTSIIFVLPLFIN--IPAYVQWQCGAIAI-YFYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVIF--MFLLL---AFGLSFYV-LLNAQDAFSSPL
LSIIQAFSMMLGDINYRDAFLEPYLRNELSYPVLSFAQLITFTIFVPIVLMNLLIGLAVG
DIAEVQKHAALKRIAMQVELHTSLEKKLPLWFLRKVDQKSTTVYPNRPRNSGR-L-FRLF
CYIFCSNETR-QEIPNTDT--SLEMEILKQKYRLKDLTFLLEKQHELVKLIIQKMEIISE
AEDEDTHSSFQDQF-KKEQLEQRNSKWNSVLRAVKAKTYRSEG-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------ILVEHSSTDINLEGENGNTALIITCFKDNSE-ALQILLNKGAN
LCKSNKWGCFPIHQAAFSGAKKCMEIILKF-GEEHGYSRLSHINFV--NN

PF00023 // ENSGT00920000149074_1_Domain_12 (351, 383)

GKASPLHMAV
QSGDLEMIKMCLDNGAQLDLVEK-GKCTALHFAATQGATEIVKLMISSYSGSSDIVNAVD
GNQESLLHK---ASLFDHHELADYLISVGAD--IDSTDS

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLILATASASWNTVNL
LLSKGARVDIKDHLGRNFLHLTVQQPYGLKNLRPEFMQMQHINQXXXXXXXXXXXXXXXX
XXXX-------------------------------------------------------X
XXXXXXXXXXXXXXXXXXXXKVVQLLWKKGAFF---FXXHNGWTALHHASLGGYTQTMKV
ILDTNMKCA-DRPDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 708)

EGNTALHFAAREGHAKAVALLLSYNADIVLNK

ENSGT00920000149074_1_Linker_47_48 (708, 940)

QLASFLHVAIHNK
RKEVVLTTIKNKRWEECFMVFSHYSP----SNKCPVLEMVEYLPECMKVLLDFCMIPSTE
DKSSHDYHIEYNFRYLQCPLEFTKKVTPIQDVTYEPLKTLNVMVQHNRTELLNHPVCKEY
LLMKWLAYGFRAHVMNVGSSCLGLLHMTSLVVNIRPGMAFNSTG---------IINETSD
-----HSEILDTK---NSY--------------TIKVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

ILVLLSSIFGYCKEVAQIFQQ
---KRNYFLDNKNALEWVIYTTSIIFVSPLFID--IPAYVQWQCGAIAV-HFYWIN-FLF
YLQRFEKCGIFIVMLEVIMKTLLKSTVVF--AFLFV---AFGLSFYV-LLSVQDAFSSPL
LSVMQTFSMMLGDISYRDAFLEPFLRNKLAYPILSFAQLIFFTIFVPIVLMNLLIGLAVG
DIAEVQKHALLKRTAMQVELHTSLEKKLPLWFLHKVDQKSIVVYPNRPRYGGGLL-RGVF
HYIFCTQEAR-QEIPNVDT--SLETEIVKQKYRLKDLSSLLEKQHELIKLIIQKMEIISE
TEDEDYHSSFQDRF-KKQQLEQRNSKWNSVLRAVKAKTQCPHG-------

------------------------------------------------------------
------------------------------MRRSLRKMLRP-GDKKKSQSVDYQGVEDDM
DDSKD-------SLKXXXXX-XXXXXXXXXXXXX-XXX--X-XXXXXXXXXXXXXXXXXX
XXX-----XXXXXXXXXXVNMMDN

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWAAGKNQVESVKFLLSKGANPNLRNNNMM
APLHLAVQGL-HNEVVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXLKHGAK
PCKSNKWGCFPIHQAAFSGAKNCLEIILKY-GDEHGYPRQNHINFV--NNGKSSPLHMAV
QGGDLEMIKLCLDNGAKLDMMET-GKCTALHFAATQGATEIVKLMISSYSGNIDIVNAVD
G

PF00023 // ENSGT00920000149074_1_Domain_15 (422, 459)

NQETLLHR---ASLFDHHELAEYLISMGAD--INAID

ENSGT00920000149074_1_Linker_15_21 (459, 460)

C

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATTSASWNVVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

NFGRNFLHMIVQQSHGLKNLQPEFMQMQHIKELVMDEDF

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

EGCTPLHYA
CRQGIPFSVSNLLCYNVSINSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDL

PF00023 // ENSGT00920000149074_1_Domain_34 (606, 640)

HGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASLGGYTQTMKV
ILDTNVKCT-DRLDEEGNTALHFAARAGHAKAVLLLLSYGADIVLNKQQASFLHVAIHNK
RKDVVLTTIRSKRWEQCLEVFSHHSP----SNRCPVMEMVEYLPDCMKVLLDLCMMPSTE
DKSCRDYYIEYNFTYLQCPLEFTKKESSLQTVTYEPLTTLNVMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHIMNLGFYCLGLLPMTFLVVNIKPGMAXXXXX---------XXXXXXX
----X----XXXXXXXDSY--------------VIKVCMILVFLSSIFGFCKEVVQIFQQ
XXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX--XXXXXXXXXXXXXX-XXXXXX-XXX
XXXXFENCGIFIVMLEVIMRTLLRSTVVF--VFLLL---AFGLSFYV-LLNLQXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGLAVG
DIAEVQKHALLKRIAMQVELHTNLEKKLPLWFLNKVDQKSVIVYPNRPRYGRGL--FCLF
RRLFSAPEAR-LEMPNVDT--ALETEILRQKYRLRDLTSLVEKQHDLIKLIIQKMEIISE
AEDDDNHNSFQDRF-KKEQLEQRNSKWNSVLKAVKEKTHHSKP-------

------------------------------------------------------------
------------------------------MKRSLRKLLRS-GE-KEPQGVAYQGVEDG-
-------MPDSKDFKVVFEG-NECR

PF12796 // ENSGT00920000149074_1_Domain_0 (146, 236)

LQQFIKNRW-KLN--KYEEENVSALHHAAGEGELE
LMK-----MIISGSSCEVLNVMDNYGNTPMHWAAENNQVESIKFLLSRGANPNLRNSSMM
APLHIAVQGM-HNEMAKVLTEHSSTNVNLEGENGNTAVMITCAKDNSE-ALEILLKKGAK
LCKSNKWGDFPVHQAAFSGAKKCMELILKF-GEEDGYSRQSHINFV--NNKQASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGNLEMIKMCLDNGAHIEKTEN-GKCMALHFAATQGATEIVKLMISSYSGSSDIVNALD
GNHETLLH-R--ASLFDHHELADYLISVGAD--INITDSEG-RSPLVLATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHFTVQQPYGLKNLRPEFMQMQEIK

PF12796 // ENSGT00920000149074_1_Domain_22 (524, 593)

ALVMDEDDDGCTPLHYA
CKQGVHVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLNYDANIVLNKQKASFLHIALHNK
RKEVVITTIRNKRWDECLKVFTHSSP----SNKCPIMEMIEYLPECMKILLDFCMIPSTE
DKSCQDYHIQYNFRYLQCPLELTKTLTSDQEVQYEPLAILNVMVQHSRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVINIKPGTAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETCD
-----HLEVLDTT---NSY--------------PIKVCMILVFLSSIFGYCKEVVQIFQQ
---KRNYFLDYNNALEWIIYTKSIIFVLPLFVN--IPAYVQWQCGAIAI-FLYWMN-FLM
YLQRFENCGIFIVMLEVIFRTLLRSAGVF--IFLLL---AFGLSFYV-LLNVQDAFSTPL
LSLVQTFTMMLGDVNYRDAYLEPFLRNELAYPVLSFAQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVDLHTSLEKKLPIWFLRKVEQRSIVVYPNRPRYGR-M--LRLF
HYFFGIQETK-QEIPNTDT--CLELEMLKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDADNHSSFQDRF-KKERLEQMNSKWNFVLRAVKTKPHSPTSHPDLQ--

------------------------------------------------------------
------------------------------MKRSLRKILRP-GEKKEPQDLGYQGVQVDM
DDC-------KESLKVVFEG-SACVSQNFIQKQK

PF12796 // ENSGT00920000149074_1_Domain_0 (155, 236)

-RLN--GKDDTNASPLHHAAAEGQVE
LMN-----MIINDSSCEVLNVMDDYGNTPLHWAAEKNQVESVKFLLSKGANPNLRNSTMM
AALHVAVQAV-HNEVVKVLTEHSSTNVNLEGENGNTAVLMACTKDNSE-ALQILFNKGAK
TCKPNKWGCFPVHQAAFSGAKKCMEIILKF-GEENGYSRKSHINFV--NNGKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHMAV
QSGDLEMIKMCLDNGALIDLMEN-GRCMALHFAATQGATEIVKLMISSYSGSTDIVNAVD
GNQETLLHR---ASLFDHHELADYLISVGAD--INSIDCEG-RSPLILATASASWNIVNL
LLSKGARVDIKDHYGRNFLHLTVQQPYGLKNLRPEFMQMQHI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KELVMDEDNDGCTPLHYA
CREGVPVSVNNLLDFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHAAMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGQAKAVGLLLSRDADIVLNKQQASFLHLALHNK
RKEVVLTAIRTKRWDECLKVFSHHSS----SNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCLDYHIEYNFKYLQCPLEFTKKGRPTQNVVYEPLTALNAMVQYNRIELLNHPVCKEY
LLMKWVAYGFRAHMMNLGSYCLGLIPMTLLVVNIKPGMAFNSTG---------IINETSD
-----HLEILDTT---NSY--------------PIKVCMILVFLSSLFGYFKEVAQIFQQ
---KSNYFRDINNLLEWIIYTTSIIFVLPLFSN--IPAFMQWQCGAIAI-YLYWMN-FLL
YLQR--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------MKRSLKKMWRP-GEKKEPQGVVYEDVPDDT
EDC-------KESLKVVFEG-SAYGLQNFN-KQK-KLK--RCDDMDTFFLHYAAAEGQIE
LME-----KITRDSSLEVLHEMDD

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 236)

YGNTPLHCAVERNQIESVKFLLSRGANPNLRNFNMM
APLHIAVQGM-NNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEIILRF-GEEHGYSRQLHINFM--NNGKATPLHLAV
QNGDLEMIKMCLDNGAQIDPVEK-GRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTD
GCH

PF00023 // ENSGT00920000149074_1_Domain_18 (424, 458)

ETMLHR---ASLFDHHELADYLISAGAD--INKT

ENSGT00920000149074_1_Linker_18_21 (458, 462)

DSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNIVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

NFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 562)

DGCTPLHYA
CRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 703)

DGNTALHFAAREGHAKAVALLLSHNAD

ENSGT00920000149074_1_Linker_47_48 (703, 952)

IVLNKQQASFLHLALHNK
RKEVVLTIIRSKRWDECLKVFSHNSP----GNKCPITEMIEYLPECMKVLLDFCMLHSTE
DKSCRDYYIEYNFKYLQCPLEFTKK-TPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEY
LLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMAFNSTG---------IINETSD
-----HSEILDTT---NSY--------------LIKTCMILVFLSSIFGYC

PF00520 // ENSGT00920000149074_1_Domain_48 (952, 1137)

KEAGQIFQQ
---KRNYFMDMSNVFEWIIYTTGIIFVLPLFVE--IPAHLQWQCGAIAV-YFYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--VFLLL---AFGLSFYI-LLNLQDPFSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGMLF--HVF
CFLFCTGEIR-QEIPNADK--SLEMEILKQKYRLKDLTFLLEKQHELIKLIIQKMEIISE
TEDEDSHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEP-------

------------------------------------------------------------
------------------------------------------------------------
---------------------NECRLQHIIKNRW-K

PF12796 // ENSGT00920000149074_1_Domain_0 (157, 236)

LN--KYEEENVSALHHAAGEGQLE
LMK-----MIISGSSCEVLNLMDNYGNTPMHWAAENNQVESVKFLLIHGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 240)

NNNM

PF12796 // ENSGT00920000149074_1_Domain_6 (240, 303)

M
APLHIAVQGM-HNEMAKVLIEHSSTNINLEGENGNTAVMITCTKDNSE-ILEILLKKGAK
LCKSNKWGDFPVHQAAFSGAKKCMELILKF-GEWNGYSRQCHINFV--NNKQVSPLHLAV
QSGNLEMIKMCLDNGAHIEKIEN-GKCMALHFAATQGATEIVKLMLSSYSGNSDIINAVD
GNHETLLH-R--QVSYQ--SFSDYLISVVTI--Q-LMDLFYLTTIYSSKNCKKNFHICNL
--VFCARVDIKDYLGRNFLHFTVQQPYGLKNLRPEFMQMQEIKALVMDEDNDGCTPLHYA
CKQGVH------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------IEYNFRYLQCPLQFTRKLPVEQEVHYEPLSTLNVMVQHNRIELLNHPSTEL-
------------------------------------------------------------
---------TFYK---NSY--------------PIKVCMILVFLSSIFGYCKEVIQIFQQ
---KRNYFLDYNNALEWVIYTKSIIFVLPLFVS--IPAYVQWQCGAIAI-FLYWMN-FLM
YLQR-----------------------------------------------------SPL
LSLVQTFTMMLGDVNYRDTYLQPFLKNELTYPVLSFVQLIAFTMFVPIVLMNLLAL---G
S---------------ISKLHTSLEKKLPIWFLRRVDQKSTIVYPNRPRYGP-V--LRLF
HYFFGVQETR-QELPNTDT--CLELEMLKQKYRLKDLTSLLEKQHELIKLIIQKXXXXXX
TEDEDNHSSFQDRF-KKERLEQMNSKWNFVLRAVKTKISHQDL-------

------------------------------------------------------------
------------------------------MKCSLKRMLRP-EERKELQGVVYRGVEEDM
DY-------SKDSFKVDIEG-DRYRLEHFMKHRR-KLS--KYED

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

ENISPLHHAAAEGQVE
LMK-----MIIHGSSCEVLNIMDSSGNTPLHWAAEKNQVESVKFLLSQGANPNLRNNNMM
APLHIAVQAS-YNEMTKVLVEHTTTNINLEGENGNTALMSTCAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILKY-GEEHGYKREFHINFV--NHKKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGDLDMIKMCLDNGAHIDMIEN-GKCMALHFAATQGATDIVKLMISSYTGSNDIVNAVD
GNHETLLH-R--ASLFDHHDLADYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLKNLQPEFMQMQHI

PF12796 // ENSGT00920000149074_1_Domain_22 (523, 593)

KELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKQHASFLHIALHNK
RKEVVLTTIRSKRWDECLQVFSHYSP----SNRCPITEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLSLTKKVTPTQDVVYEPLTILNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTFLVVKIKPGLAFNSTG---------II

PF00520 // ENSGT00920000149074_1_Domain_48 (896, 1149)

NETT-
----DHLETVDTL---NSF--------------PIKVCMILVFLSSLFGYCKEVVQIFQQ
---KRNYFLDYNNALEWVIYTTSIVFVLPLFLN--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFSLSFYV-LLNFQDAFSSPL
LSLIQTFTMMLGDINYRDAFLEPLLKKELAYPILTFGQLILFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQKSTIVYPNRPRHGR-M--LRFF
HYFLWTQETR-QEVPNTDM--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDKF-KKERLEQMQSKWNFVLNAVKTKTH-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LNVLDI

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

SGNTPLHWATEKKQVENVKFLLSRGANPNICN

ENSGT00920000149074_1_Linker_2_4 (237, 238)

N

PF00023 // ENSGT00920000149074_1_Domain_4 (238, 257)

NSM
SPLHLAIQCF-YNEIVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XEEQGYSRQYHI----FLNNKSSPLHL-V
QSGDLEMIKICLANGAQIKLEEN-GKCTALHFAATQGATEIVKLMISSYTGGDDIINTXX
XXXXXXXXXX---XXXXXXXXXXXXXXXGAD--INSIDC

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATSSASWNVVNL
LLSKGADVGIKDYFGRNFLHLTVLQPCGLKHLNQEFLQXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXKSK

PF00023 // ENSGT00920000149074_1_Domain_23 (565, 602)

DNKSPLHF-----AANFGRINTCQRLVRDMTDTRLL
NEGDQNGMTPLHLAAKNGHDKVVKFLLKKGALF---LSDHNGWTALHHASMGGYTQTMKI
ILDTNVKCT-DHVDEEGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXWEECLTVFSPVSL----TNKCPXXXXXXXXXXXXXALLDICIVESSE
ERSCPNFHXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXAMVQHNRRELLVHPVCREY
LLMKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------XXXXXX
XXXXXXXXXXXXXXXXNSY--------------LISACM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

ILIFLSSVFGFCKEMIQIVQQ
-----RYFLDPTNLIEWIIYTTSIVFVSPXXXXXXXXXXXXXXXXX----XXXXXXXXXX
XXXXFENCGIYVVMLLEVTKTLLKTTFVF--FFLIL---AFGLGFHVLLGLQ-NAFKTPM
LSIMQTFSMMLGDINYHEGFLHPFLEKSLPYPFLSFLFLVVFTLYIPIVLMNLLIGLAVG
DIAEVQKNASLKRIAMQVKLHTSLEKKLPFWFLSKVDQESIIVYPNRRRHCGIMS---LF
HYWFCTRYTK-PETHCADK--TLEVEVLKQKYRLKDLALLLEKQHDLIKLIIQKMEIISE
AEDEDSSFSFQHRF-RHQQLE-KSSKWHCVLKAVKKKAMCAHH-------

------------------------------------------------------------
------------------------------MKRGLRRILLP-EERKEVQGVVYRGVGEDM
DC-------SKESFKVDIEG-DMCRLEDFIKNRR-KLS--KYED

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

ENLCPLHHAAAEGQVE
LME-----LIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQGANPNLRNRNMM
SPLHIAVHGM-YNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSE-ALQILLEKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILAY-GEKNGYSRETHINFV--NHKKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGDLDMIKMCLDNGAHIDMMEN-AKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVD
GNQETLLH-R--ASLFDHHDLAEYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLCKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LS

PF12796 // ENSGT00920000149074_1_Domain_42 (639, 705)

DHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAMLLSYNADIL

ENSGT00920000149074_1_Linker_42_48 (705, 939)

LNKKQASFLHIALHNK
RKEVVLTTIRNKRWDECLQVFTHNSP----SNRCPIMEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLSMTKKVAPTQDVVYEPLTILNVMVQHNRIELLNHPVCREY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTG---------IINGTSS
----THEERIDTL---NSF--------------PIKIC

PF00520 // ENSGT00920000149074_1_Domain_48 (939, 1149)

MILVFLSSIFGYCKEVIQIFQQ
---KRNYFLDYNNALEWVIYTTSIIFVLPLFLN--IPAYMQWQCGAIAI-FFYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNFQDAFSTPL
LSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQRSTIVYPNRPRHGR-M--LRFF
HYFLNMQETR-QEVPNIDT--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKERLEQMHSKWNFVLNAVKTKTHCSISHPDF---

------------------------------------------------------------
------------------------------MKRSLKKMLRL-GEKKELQSAVYDGVEVDT
DSCKD--FVKXXXXXXXXXX-XXXXXXXXXXXXX-XXX--XXXXXXXXXXXXXXXXXXXX
X-X-------XXXXX-XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXVLAEHRSTNINLEGENGNTALLIACSKDNSE-ALQILFNKGAK
PCIPNKWGCYPV-QAAFSGAKNCMELVLKFXXXXXXXXXXXXXXXX--XXXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXN-

PF00023 // ENSGT00920000149074_1_Domain_13 (385, 418)

GKCTALHFAATQGATETVKLML-SYCGESDVVNTVD
GNQETLLHR---ASLFDHHELAEYLISVGAN--INSIDS

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATASASWNTVNL
LLSKGAQVDIKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

HLGRNFLHLTVQQRYGLKNLRPEFMQMQHIKELVMDEDN

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

NGCTPLHYA
CRQGVPVSVNNLLHFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTWLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALL---LSDY

PF00023 // ENSGT00920000149074_1_Domain_45 (641, 672)

NGWTPLHHASIGGYTQTMKV
ILDTNLKCT-DQLDEEGNTALHFAAREGHAKAVGLLLSYDAEIILNKQDASFLHVAIHNR
RKEVVLTTIRNKRWDECLKTFSHYSQ----CNRCPLMEMVEYLPECMKVLLDFCMLHSTE
DKSCREYHIEYNFRYLQCPLELTKKISPVKDVTYEPLTALNXXXXXXXXXXXXXXXXXXX
XXXXXLAYGFRAHIMNLGSYCLGLIPMTFLVINIKPGMGFNSTG---------IINETSN
-----HSEILDTK---NSY--------------SIKVCMILVFLSSIFGYCKEVAQIFQQ
---KRSYFGDHSNADEWVIYTTSIIFVLPLFTS--IPAHVQWQCEAIAI-FFYXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX---XXXXXXXX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGLAVG
DIAEVQKHASLKRIAMQVKLHTNLEKKLPLYFLRKVDQQSIIVYPNRPRYQGGL--MCIF
HYMFSIQEAR-QETPNIDA--SLETEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDKF-KKEQLEQRNSKWNSVLRAVKEKTQWSY--------

------------------------------------------------------------
--------------------------------------MWC-WG-IEPQSLCFAKLVLSR
CSRPL--SHLTSPSFVTFEG-NECRLQHFIKHRW-

PF12796 // ENSGT00920000149074_1_Domain_0 (156, 236)

KLN--KYEEENVSPLHHAAGEGQLE
LMK-----LIISGSSCEVLNVMDNYGNTPMHWAAENNQVESIKFLLSHGANPNLRNSSMM
APLHIAVQGM-HNEMTQVLTEHSTTNINLEGENGNTAVMITCAKDNSE-ALEMLLKKGAK
LCRPNKWGDFPVHQAAFSGSRKCMELILKF-GEQAGHSRQSHINFV--NNKEASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGNLEMIKMCLDNGAHIEKTEN-GKCMALHFAATQGATEIVKLMISSYSGSSDIVNAVD
GNHETLLH-R--ASLFDHHELADYLISAGAD--INITDSEG-RSPLVLATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHFTVQQPYGLKNLRPEFMQIQEIK

PF12796 // ENSGT00920000149074_1_Domain_22 (524, 593)

ALVMDEDNEGCTPLHYA
CKQGVHVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQSISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVALLLNYDADIVLNKQQASFLHIALHNK
RKEVVITTIRNKRYTSPMRTLRRQER----------------------KKKYFCMIPSTE
DKSCQDYHIEYNFRYLQCPLELNRKLAPGQEVRYEPLSILNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVIHIKPGTAFNSTG---------IIN

PF00520 // ENSGT00920000149074_1_Domain_48 (897, 1149)

ETYD
-----HLEILDTT---NSY--------------SIKVCMILVFLSSIFGYCKEVVQIFQQ
---KRNYFLDYNNALEWIIYTKSIIFVLPLFVS--IPAYVQWQCGAIAI-FFYWMN-FLM
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNAQDAFSSPL
LSLVQTFIMMLGDVNYRDAYLEPFLRKELAYPVLSFAQLVAFTMVVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPICFLRKVEQKSIVVYPNRPRYGR-M--LRLF
HYFFGIQEAK-QEIPNTDT--CLELEMLKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHSSFQDRF-KKERLEQMNSKWNFVLRAVKTKPHSPKE-------

------------------------------------------------------------
------------------------------MKRNKKKVLSSFGENKEPQDAVYEGVELEM
DA------SEENVFKVILEG-NVKGLQSFMMKNRDCLG--TYDELNATPLHHAAAQDQVE
LLE-----MIIDDSSLEGLNIMDHF

PF00023 // ENSGT00920000149074_1_Domain_2 (206, 237)

GNTPLHWATEKKQVENVKLLLRRGADPNICNNNLM
APLHLAIQSC-YNEIVKVLVEHSSTDVNLKGENGSTPVLLACSKDNSE-ALKLLMDRGAK
ICRPNKFGCYPVHIATFSGAKKCLEMLLKF-GEEQGYSRQFQMNFI--NNKNS

PF00023 // ENSGT00920000149074_1_Domain_12 (354, 380)

SPLHFAV
QSGDLEVIKICLENGAEINLEET-GKCTALHFAATQGATEIVKLMITSYSGNNDIINSVD
GNNETLLHRV---ALFDHHELAEYLISMGAN--IDSIDLEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 492)

-RSPLLLATSSASWNVVNL
LLSKGANVEIKDHYGRNFLHLTVLQPYGLKNLKQEFLQMKHIENLVMDEDIDGCTPLHYA
CRQGVALSVNNLLRLNVSIGTKSKDNKSPLHF-----AANFGRINTCQRLIRDMTDTRLL
NEGDQ

PF00023 // ENSGT00920000149074_1_Domain_35 (606, 631)

NGMTPLHLAAKNGHDKVVKFLLKKGALF---LSDYNGWTALHHASMGGYTQTMKI
ILDTNVKCT-DHVDEEGNTALHYAAREGHAKAVALLLDYDAQILMNKQSATFLHDAIHNR
RKEVVITTIRSKRWNECLAEFNTLSV----ANKCAVLEMVEYLPECMKTLLDICIVESSE
ERSCQNFHIEYNFKYLQSPVELRE-N-EVNNTVYGPLTTLNAMVLHNRRDLLDHPVCREY
LLMKWMAYGFRAHMMNLGLYCLGLIPMTILISNMQPVVAFNSTE---------NIN----
--STN--GESKPLDHKNSY--------------LIKVCMILVFLSSV

PF00520 // ENSGT00920000149074_1_Domain_48 (948, 1137)

FGFCKEMIQIYQQ
---KTNYFLDHTNLIEWVIYTTSIVFVLPLFVS--IPNDIQWQCGAISV-FLFWMN-FLL
YLQRFENCGIYVVMLLEITKTLLKTTFVF--FFLIL---AFGLGFHVLLGLQ-SAFYTPT
LSIIQTFSMMLGDINYHDAFLGPYLDNHLPYPLLSFIFLIIFTLYIPIVLMNLLIGLAVG
DIAEVQKNASLKRIAMQVKLHTSLEKKLPFWFLHKVDQETIIVYPNRRKNFGLMN---IF
NFFFCARYTK-PEIQSADT--PLEVEVLKQKYRLKDLAFLLEKQHELIKLIIQKMEIISE
AEDEDNNFSFQQRF-RKQQLE-RNSKWHSVLKAVKAKKKLCLIPHN----

------------------------------------------------------------
------------------------------MRRSLRKMLSP-GGKQEPQGAVYQGVENGT
DGR-------KDSLKVVFEG-STCRFN-LMKKRK-KLS--KYDDVNTSPLHHAAEEGQVQ
LMG-----MIINDSSFEVLNVMDDYGNTPL-----KN

PF12796 // ENSGT00920000149074_1_Domain_6 (218, 303)

QVESVKFLLSKGANPNLRNGNMM
APLHIAVQGL-HNEVMKVLTEHNNTNINLEGENGNTAVIIACAKDNSE-ALQILLNKGAK
PCKANKWGCFPIHQAAFSGAKKCMEIILKF-GEEHGYSRESHINFV--NNAKASPLHMAV
QSGDLEMIKMCLDNGAQLDLMEN-GKCTPLHFAATQGATEIVKLMISSYSGSSDIVNAVD
GNQETLLHR---ASLFDHHELADYLISVGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGAHVDIKDHLGRNFLHLTVQQPHGLKNLQPEFMQMQHIKKLVMDEDDDGCTPLHYA
CRHGIPVSVDNLLDFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDMNDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHSGWTALHHASLGGYTQTMKV
ILDTNMKCT-DQL

PF12796 // ENSGT00920000149074_1_Domain_47 (674, 725)

DEEGNTALHFAAREGHAKAVALLLSYDADIVLNKQQASFLHVAIHNK
RKDV

ENSGT00920000149074_1_Linker_47_48 (725, 905)

VLTTIKNKRWEECLKVFSHYSP----SNKCPVMEMVEYLPECMKVLLDCCMMPSKR
DKSCQDYYIEYNFRYLQCPLEFTKKVTPAQDVTYEPLTTLNAMVQHNRIELLNHPVCKEY
LLMKWLAYGFRAHIMNLGSYCLGLLPMTFLVVSIKPGMAFNSTG---------IINETSD
----

PF00520 // ENSGT00920000149074_1_Domain_48 (905, 1148)

-HSEILDTK---NSY--------------SIKVCMILVFLSSIFGYCKEVVQIFQQ
---KRNYILDNANGAEWIIYTTSIIFVSPLFIG--IPAYVQWQCGAIAI-YLYWMN-FLL
YLQRFENCGIFIVMLEVIMKTLLRSTVVF--VFLLL---AFGLSFYV-LLNIQDAFSSPL
LSIIQTFSMMLGDINYRDAFLEPFLRNELVYPVLSFAQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHALLKRIAMQVELHTSLEKKLPLWFLRKVDQKSIIVYPNRPRCTGL---LAIF
HFIFYTQEER-QEIPNVDT--SLETEILKQKYRLKDLTSLVEKQHELIKLIIQKMEIISE
TEDEDNHHSFQDRF-KKEQLEQRNSKWNSVLKAVKAKTHCP---------

------------------------------------------------------------
------------------------------MKRILRKMLRP-GEK-DPRGVIYEAELNDC
----------TDFFTVVFEG-STCKLQNFVKKRK-RLS--KYDD

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 204)

KNASALHHAAEEGQIE
MME-----MIINESSCEVLNEMD

ENSGT00920000149074_1_Linker_0_2 (204, 205)

S

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

YGNTPLHWATEKNQVESVKFLLSKGANPNLRNSHMM
GPLHIAVQCM-HHEVMKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXLNKGAK
PCLSNK

PF00023 // ENSGT00920000149074_1_Domain_11 (307, 340)

WGCFPIHQAAFSGAKQCMEILLKY-GDEHGCGRVSHINFI--NNGKASPLHMAV
QSGNLEMIKMCLDNGAQIDLMEN-GKCTALHFAATQGATDIVKLMISSYTGDCDIVNAVD
GNQETPLHR---VSLFDHHELADYLISVGAD--INKIDC

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

EG-RSPLLLATASASWNIVNL
LLSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DKLDE

PF00023 // ENSGT00920000149074_1_Domain_47 (676, 708)

EGNTALHFAAREGHAKAVALLLSYDADILLNK

ENSGT00920000149074_1_Linker_47_48 (708, 940)

QLASFLHVAIHNK
RKEVVLTTIRSKRWEDCFKVFNHYSQ----SNKCPLMEMVEYLPECMKVLLDFCMSYSTE
DKSCHDYHIEYNFRYLQCPLEFTKRETCPQDVTYAPLTILNTMVQHNRTELLNHPVCKEY
LLMKWLAYGFRAHLLNLGIYCLGLLPMTFLVVHIKPGMSFNATG---------IINETSN
-----HSEMLDTK---ISY--------------PITVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

ILVFLSSIFGYCKEVAQILQQ
---KSNYFLDQNNAVEWIIYTTSIIFVLPLFVS--IPARVQWQCGAIAI-FFSWMN-FLM
YLQRFESCGIFIVMLEVILKTLLRSTVVF--IFLLM---AFGLSFYV-LLSIQXXXXXXX
XXXXXXXSMMLGDVNYRDSFLEPY--RELAYPFLSFIQLISFTMFVPIVLMNLLIGLAVG
DIAEVQKHAALKRIAMQ-ELLTNLEKKLPLW-LRKVDQEYITVYPNRYRDSGSL--FGVF
QRIFCTHETK-QEIPNVDT--ALETELLKQKYRMKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDSHCSFQDRL------------------------------------

MMVISFPLVLPQEPLESREASFPSLPFPRRSFSSPPPPQADAGSLFGCGGAPGREGGRQG
RKRGLSMASPLTRCLLLVPPAGSQAARSPAMKRSLRKWLQS--GEKKA-RTSYEGVVCEA
DAASL---ASQDVFKVISDG-STSRLRSFIKKNREGLK--KLDDLNATPLHHAAGQGQLE
LMQ-----MIIDS-SSEALNVTDTS

PF00023 // ENSGT00920000149074_1_Domain_2 (206, 236)

GNTPLHWATKKNQIESVKLLLSRGANPNILNSNMM
APLHLAVQSL-RNELVKIFVEHTTTDINLEGENGNTPITIACYKDNSE-ALKLLIENGAK
ICKGNSMGWMPVHAAAFSGAKACMEILIKR-GEETGYSPENHINFT--NNGK

PF00023 // ENSGT00920000149074_1_Domain_12 (353, 381)

CTALHLAV
QSGDLEMIKMCIEYGAQIDLKQN-DKCTALHFAATQGATEILKLMMSSYTGDEPIIDALD
ENKETLLHRV---ALFDHYELAEYLITMGAK--IDSVDIEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 492)

-RTPLLLATSCASWKIVNL
LLSKGANVELKDHLGRNFLHLTVLHPGGLKHLNEQFLKMKHIKELVTDEDNDGCTPLHYA
CRQGVPLSVNSLLELDVSIYSKSRDKKSPLHF-----AASYGRINTCQRLLRDMVDTRLL
NEGDKKGMTPLHLAAQNGHEKVVQFLLRKGALF---LCDYKGWTALHHAAFGGYTRTMQI
ILNTNVKCT-DKVDEE

PF00023 // ENSGT00920000149074_1_Domain_47 (677, 702)

GNTALHLAAKEGHPKAVRLLLDDNA

ENSGT00920000149074_1_Linker_47_48 (702, 943)

KILLNKSDASFLHEAIHNG
RKEVVNATILHKRWEESMTTFSHYSS----ANKCAILEMVEYLPECLKLVLDNCMIESCE
EKTCRDFHIEYNFRYLQCPLKLTKQFKEGDEIMYEPLHNLNAMVRHNRVELLSHPVCTEY
LLMKWMAYGFKAHLMNLAVYSLGLIPLTLLIVHIERPEPPYNAT----------------
-------VKSGPFGKKNSY--------------FIKVCMCLV

PF00520 // ENSGT00920000149074_1_Domain_48 (943, 1137)

FIMSVFGICKEIVQLFQQ
---KLRYLLDYSNLLDWIIYTTSITFVSSLFIN--LPANLQWECGATAI-FLSWMN-FLL
YLQRFENFGIYVVMFWEILRTLIRIAIVF--FFLML---AFGLSFHVLLGSQ-EAYGTPY
LSVMQTFAMMLGDINYHDAFLEPMLTNKLPYPLLSYIILIVFTLLIPILLMNLLIGLAVG
DIAEVQKFAVLKRIAMQVNLHTNLEKKLPYWFLSRVDQESITVYPNRPRYCGFMS---VF
QYCFGCDDRA-SNVPSADT--SLELEVLKQKYRLKDIATLMEKQHDLLKLVVQKMEIISE
AEDEDTNDLFQHKF-RKQQLEHKNN-------------------------

------------------------------------------------------------
------------------------------MKRSLRKMLRP-AEKKEPQGVVYQGVDDDM
D----------NSFKVDCER-SVYKLHK

PF12796 // ENSGT00920000149074_1_Domain_0 (149, 236)

CMRNLR-KSN--KDEDENVSPLHHAAAEGQVE
LMK-----MIISGSSCDVLNAMDDYGNTPLHWAAENNQVGSVKFLLCQGANPNLRNSNMM
APLHIAVQGT-YNEITKVLTEHSTTDINLEGENGNTAVLSTCARDNSE-ALNILLSKGAK
LCKSNKWGDYPVHQAAFSGAKKCMELILKF-GEESGYTRESHINFV--NNKKVSP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 458)

LHLAV
QSGDLEMIKMCLDNGAHIDLQEN-GKCMALHFAATQGATEIVKMMISSYSGNNDIVNAVD
GNHETLLH-R--ASLFDHHELADYLISVGAD--INTTDSEG-RSPLILATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLKNLQPEFMQVS--------------------
-----------------------KDKKSPLHFAPVFMIYDYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNGWTALHHASMGGYTQTMKV
ILDTNLKCT-DRL

PF12796 // ENSGT00920000149074_1_Domain_47 (674, 725)

DEEGNTALHFAAREGHAKAVALLLNHDADIVMNKQQASFLHIALHNK
RKEVVLTTIRSKRWDECLKVFTHHSP----SNRCPIMEMVEYLPECMKILLDFCMIPSTE
DKSCRDYHIEYNFKYLQCPLTFTKKITPTQEVVYEPLSILNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVHIKPGMAFNSTG---------IFNESSD
-----HLEILDTT---NSY--------------PIKVCMILVFLSSIFGYCKEVTQILQQ
---KRNYFLDYNNALEWIIYTTSIIFVLPLFVS--IPGHVQWQCGAIAI-FFYWMN-FLL
YLQRTTFLGIYAYNFLKVFVIYFLSIGLHKRPFNCL---HFVFNFYL-TLFFQDAFSSPL
LSLIQTFSMMLGDINYRDAFLEPFLRKELAYPVLSFAQLIAFTMFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPVWFLRKVDHKSTIVYPNRPRHGK-I--LRLF
NYFFGTQETR-QEIPNTDA--CLEMEILKQKYRLKDLSSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDSF-KKERLEQMNSKWNFVLRAVKTKTHSPKH-------

------------------------------------------------------------
------------------------------MKRSLKKMWRP-GEKKEPQAVLYEDVPNDT
DDC-------KESLKVVFEG-STCGLQNFK-NQK-ILN--RCNN

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

VD-ISLHYAAAKGQVE
LME-----KITRDSSFEVLNAMDDYGNTPLHCAVEENQIESVKFLLSRGANPNLRNFNMI
APLHIAVQGT-HNEVMKVLLEHRSIDINLEGENGNTSVIIACTKNNSE-ALQILLNKGAK
PCKSNKWGCFPIHQAAFSGSKECMEILLRF-GEEHGYNRQLQINFV--NNGKASP

PF12796 // ENSGT00920000149074_1_Domain_13 (356, 457)

LHLAV
QNGDLEMIKMCLDNGAQIDLVEK-GRCTALHFAATQGATEIVKLMISSYSGGMDIVNTTN
GSGETMLHR---ASLFDHHELADYLISVGAD--INS

ENSGT00920000149074_1_Linker_13_21 (457, 462)

IDSEG

PF00023 // ENSGT00920000149074_1_Domain_21 (462, 493)

-RSPLILATASASWNVVNL
LLSKGAQVNIKD

ENSGT00920000149074_1_Linker_21_22 (493, 548)

NFGRNFLHLTVQHPYGLKNLRPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGGPG

PF12796 // ENSGT00920000149074_1_Domain_22 (548, 631)

SVNNLLGFNVSINSKSKDKKSPLHF-----AASYGRINTCQRLLQDITDTRLL
NEGDLHGMTPLHLAAKNGHEKVVQLLLKKGALF---LSDHNGWTALHHASVGGYTQTMKVILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHVALHNKRKEVVLTTIRSKRWDECLKVFCHNSP----GNKCPITEMIEYLPECMKVLLDFCMLPSTEDKSCRDYYIEYNFKYLQCPLEFTRKTTPTQDITYEPLIALNAMVQNNRIELLNHPVCKEYLLMKWMAYGFRAHMINLGSYCLGLIPMTFLVVNIKPGMAFNSTG---------IINETSD-----HSEILDTT---DSY--------------LIKTCMILVFLSSIFGYCKEVVQIFQQ---KRNYFMDINNIIEWIIYTTGIIFVLPLFIE--IPAHVQWQCGAVAI-YLYWMN-FLLYLQRFENCGIFIVMLEVILKTLLRSTVVF--VFLLL---AFGLSFYV-LLNLQDAYSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAYPVLSFAQLIFFTLFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGILF--HIFFCLFCTGEIR-QEIPNADT--SLEMEI

PF12796 // ENSGT00920000149074_1_Domain_23 (548, 631)

SVNNLLGFNVSINSKSKDKKSPLHF-----AASYGRINTCQRLLQDITDTRLLNEGDLHGMTPLHLAAKNGHEKVVQLLLKKGALF---LSDHNGWTALHHASVGGYTQTMKV
ILDTNLKCT-DRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHVALHNK
RKEVVLTTIRSKRWDECLKVFCHNSP----GNKCPITEMIEYLPECMKVLLDFCMLPSTE
DKSCRDYYIEYNFKYLQCPLEFTRKTTPTQDITYEPLIALNAMVQNNRIELLNHPVCKEY
LLMKWMAYGFRAHMINLGSYCLGLIPMTFLVVNIKPGMAFNSTG---------IIN

PF00520 // ENSGT00920000149074_1_Domain_48 (897, 1149)

ETSD
-----HSEILDTT---DSY--------------LIKTCMILVFLSSIFGYCKEVVQIFQQ
---KRNYFMDINNIIEWIIYTTGIIFVLPLFIE--IPAHVQWQCGAVAI-YLYWMN-FLL
YLQRFENCGIFIVMLEVILKTLLRSTVVF--VFLLL---AFGLSFYV-LLNLQDAYSSPL
LSIIQTFSMMLGDINYRESFLEPYLRNELAYPVLSFAQLIFFTLFVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNKPRSGGILF--HIF
FCLFCTGEIR-QEIPNADT--SLEMEILKQKYRLKDLTCLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KKEQMEQRNSRWNTVLRAVKAKTHHLEH-------

------------------------------------------------------------
------------------------------MRCSLRRMLRP-EERKEIQGVVYRGVEEDM
DC-------SKESFKVAIEG-DMYRLEDFVKNRR-KLS--KYED

PF12796 // ENSGT00920000149074_1_Domain_0 (165, 236)

ESISPLHHAAAEGQIE
LMK-----MIIHGSSCEVLNTMDNCGNTPLHWAAEKNQVESVKFLLSQGANPNLR

ENSGT00920000149074_1_Linker_0_6 (236, 240)

NSNM

PF12796 // ENSGT00920000149074_1_Domain_6 (240, 303)

M
APLHIAVQAM-YNEMTKVLTEHITTNINLEGENGNTALMSACAKDNSE-ALQLLLEKGAK
LCKSNKWGDYPVHQAAFAGAKKCMELVLNY-GEKHGFTKESHINFV--NHKKASPLHLAV
QSGDLDMIKMCLDNGAHIDMIEN-GKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVD
GNQETLLH-R--ASLFDHHDLADYLISAGAD--INSTDSEG-RSPLILATASASWNIVNL
LLSKGAKVDIKDHLGRNFLHLTVQQPYGLKNLRPEFMQMQHIKELVMDEDNDGCTPLHYA
CRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHF-----AASYGRINTCQRLLQDISDTRLL
NEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALF---LSDHNG

PF13637 // ENSGT00920000149074_1_Domain_46 (643, 697)

WTALHHASMGGYTQTMKV
ILDTNLKCT-DRLDEEGNTALHFAAREGHAKAVAML

ENSGT00920000149074_1_Linker_46_48 (697, 905)

LSYNADIVLNKQQASFLHIALHNK
RKEVVLTTIRSKRWDECLQVFSHYSP----SNRCPTMEMVEYLPECMKVLLDFCMIPSTE
DKSCQDYHIEYNFKYLQCPLAMTKKLTPTQDVRYEPLTVLNVMVQHNRIELLNHPVCKEY
LLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIKPGMAFNSTG---------IINETS-
----

PF00520 // ENSGT00920000149074_1_Domain_48 (905, 1149)

NNLDPVNTL---NSF--------------PITICMVLVFLSSIFGYCKEVVQIFQQ
---KRNYFLDYNNALEWIIYTTSIIFVLPLFLN--IPAYMQWQCGAIAI-FLYWMN-FLL
YLQRFENCGIFIVMLEVIFKTLLRSTGVF--IFLLL---AFGLSFYV-LLNFQDAFSTPL
LSLIQTFSMMLGDINYRDAFLEPFLRKELAYPILTFGQLIAFTMSVPIVLMNLLIGLAVG
DIAEVQKHASLKRIAMQVELHTNLEKKLPLWYLRKVDQKSTIVYPNRPRHGR-M--LRFF
HYFLCTQETR-QEVPNTDM--CLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISE
TEDEDNHCSFQDRF-KRERLEHMHSKWNFVLNAVKTKPHCPISHSDL---

------------------------------------------------------------
------------------------------MRRSIRRILSSTAK----KDNVYEGVFLQT
GSVCSLDDNPLLIFKLIAEG-NVCRVRNFVLKNPGSLA--ARDD

PF00023 // ENSGT00920000149074_1_Domain_0 (165, 204)

SEATPLHHAAKLGNID
LML-----MIVNESAEEGINALD

ENSGT00920000149074_1_Linker_0_2 (204, 205)

S

PF00023 // ENSGT00920000149074_1_Domain_2 (205, 237)

RGNTPLHWAVQKNKLDCLKVLLCRGADPNIQN

ENSGT00920000149074_1_Linker_2_5 (237, 238)

C

PF00023 // ENSGT00920000149074_1_Domain_5 (238, 272)

YRL
SPLHLAIQLF-HNSIAEALILHSTTDINLEGDLGNTPVMQACCKDNHE-ALNLLLGRGAK
LCKQNKLGCYPIHMTAFMGSLKCMDIILKK-GEEMGYTIDHHINFT--NNEKSSPLHLAV
QNGNIDVVKACISYGAKIDLRQS-DNATALHFAATQGATEIVKFMVSSYSDDNKIVDLPD
GNDETPLHKS---VLFDHVELAEYLISEGAN--IDSEDK

PF00023 // ENSGT00920000149074_1_Domain_21 (460, 493)

ES-RTPLLLATSCSAWKSVNL
LLSKGADVKLKD

ENSGT00920000149074_1_Linker_21_22 (493, 532)

HYGRNFLHLMVLQPGGLKNLNSEFLQMENIKKLVSDEDC

PF00023 // ENSGT00920000149074_1_Domain_22 (532, 564)

EGCTPLHYA
CRHGVPNSVNNLLGLNMSLYSKS

ENSGT00920000149074_1_Linker_22_23 (564, 565)

K

PF00023 // ENSGT00920000149074_1_Domain_23 (565, 602)

NKRSPLHF-----AACYGRFNTCQRLLRFMSDGRLL
NDGDEKGMTPLHLAAENGHEKIVFLLLKRGALLLRILSDHRGWTALHYAALSGYTRTIKT
LLETSIGLI-DKTDKEQNTAMHLAGREGHAKAVSLLLENGASILLNANGASYIHEAIRFG
KKDTVLVSIQSERWEEILQTFSHTSS-----YKCAILEMIYHLPESFKTLLDRCMTESIG
DKKSPDFHVEYNFTYLQCPLSFRKAHKRENNVHYEPLTTLNAMVQHQRIDLLSHPVCKEY
LLMKWMAYGFKAHLLNLAIYSLGLIPLTLLIINAVRPESLAIIEECEHLKRTDFYNSSMK
QECANVSRKLDLLQLKDTQ--------------YTRVCM

PF00520 // ENSGT00920000149074_1_Domain_48 (940, 1138)

GLVFCMSLFGIVKEAVQLCQQ
---KLAYIGDGSNIIDWSIYISSIIFVSSLCHSPIVVSGLQWQFGAIAV-FASWVN-FLI
YLQRFESYGIYIVMFWEILRTLLRIVFLF--FFLIL---AFGLSFYVFLYPQ-VTFSRPY
FALMQSFTMMLGDINYEEGFLKPLLDDQIEYPFFTFIHLIMFTLLIPILLMNLLIGLAVG
DIAEVQRNACLKRIAMQVSLHTSLEKKLPFWFLKRVDKISITVYPNRPRIWGITFTSNFF
HYFSSCDDVK-AEIPINDE--TMELELWKQKNRLKDLTTMMQKQNDLIKLIIQKMEIVSE
AEDEDGDNICQSKMMKKQKLDRKESKWDCVAKAVKSCKNV----------