Query Results 

------------------------------------------------------------
----------------------------------MAELKVETRGSVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSAG
SLHRKYQDLLKAMQGKDELIGQLEAQLEKQKQMRAEEAKIVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------TPSGKLLVAPQGTVEQDSVPSGPGAQPVGQ
D----------SDTRA---------------QSPLKAAMPA--PSPGPPQ-SKDSVPKAG
SPVEDS------GSVMVHPGEVSETKTPPTHLGRQGS---------------PGQLCV-K
PRTPRHGLVSWGEG-------------LVTAQ-GGTLPGTKTSAREGGPGCSLTLPKARA
SSTPRDSIQLAKRHHSQPQAGPGHFSHVVSIEIGALSALRPASPPKA---E--AELREEP
EKMEMEEQPPAGKEE---------------APGTVLEEVDLGNKPPTPPLHRFPSWES-R
IYAVATSGMRLSEVSARSNTTGPWW--VGWASSSPPVLGSP-GPFSGLVYKNVTVPVYTA
LKGRATQISTVPFVDESSGSDDDCSSQASFRTSVPCSESRRTSGLEPP------GVS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYS-T--DG--LSLGG----

PF00169 // ENSGT00920000149052_1_Domain_0 (893, 1018)

KSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCR-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QTIGPPALPQGGTKPTVKGWLTKVKHGHSKLVWCALIGRTFYYYRT-----TLGRLPVRD
ACIEEVDRSCDSDEDYEA-GGTGRLRSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLV-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQEAGMRTSSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHSGKSE
GGSRVVKLIYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLASQASGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPVLPGPGVTPPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADQLTTKWAALQGCSSSECVRIYLTVARKWPFFG
AKLFAAQPAELSSKE-NAPVWIAVNEDGVSILDHNTMQVHVTYPYASVMTFGGYRDDFM-
-LVIRSIPDQGSGRSHIEKLIFRMAAPKIAEVTFIVASYMNHCSTAV-SPPT--------
--NPPAACQPWELDARHFFASVPRAAKGPTLL

------------------------------------------------------------
----------------------------------MAELKVEMLANVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAEDAETQVGVMEEKVKLSNLKNVDSVG
SLHRKNQELLKAMQGKDELISQLEAQLKAQKQMRAEEAKVVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQRLVDQVGALQSALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVAPQETPEQDPLPSGPGTQSTGQ
D----------SGSQT---------------QGALKVAVPA--PSPGAPQ-DKDSVREAG
SPLEDS------HPRLVHPWETGEARTPPSYLGREGS---------------PGPLCV-K
PHTPRCASASWGEG-------------LVSAQ-GGLHPAAK----ISGPGSSLTLPKVRA
PGTHWDGVQLAKRHHSQPQVHPGHFDHMVTVEIGALSARYPSDHSQVD-TQ--AELQDVP
EKMEMEDPPAKGKKEEREN---------PKAARAELEEVELGSKPPTPPLHRFPSWES-R
IYAVATSGMRLSDVSPRSNASCCGRK-SESKASSPPALESP-GPFSGLVYKKVTVPVYTA
LKGKALQISNVPFVDESSGSDDDCSSQASFRTSVPCSESRKTSGLGSPRAIKR-GVS-MS
SLSSESDYAIPPDACSLDSDYSEPEHKLQRTSSYS-T--DG--LGLGRESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVQGEGAKTFQLISEKKTYHLTADSPSLLEEWIQVLQSLLKV
QATGPPTLPQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPMRD
AHVEEVDRSCDSDEDYEA-GGIRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SANVGTAYEQLIGKLMDGE-GDPDSPLWKHPMLCYSKDGLYSSLTTLPSEAL
QTEALKLFKS--CQLFINVPLEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLT-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1463)

ILLRNPFNHSSPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHNGFSLFTDDPSGRDLEHYLQGSIKICDAISKWEQALKELHPGKSE
GGTRIVKLMYKNRLYFRSQVKG

PF00373 // ENSGT00920000149052_1_Domain_4 (1463, 1624)

ETERERLLLASQTNGELVAGRFPVNKELALEMAALMA-
QVEYGDLERSNLPGPGGTPPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFATQPAQLSSKE-NTLVWIAVNEDGVSILDHDTMQVHVTYPYSSVMTFGGCQDDFM-
-LVIRSMSDQSSGKGHIEKLIFQMAAPKIAEASFVMASYMNHCSATV-SPPT--------
--NPPAAHQL----------------------

------------------------------------------------------------
----------------------------------MAELKVETRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVD-AG
SLHRKYQDLLKAMRGKDELISQLEAQLEKQKQMRAEEAKVVQEKAAKIKEWVTLKLGELE
-MENQHLKSSNEHLAEQVGALQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVAPQETPEQDSDASGPGVQPIGQ
D----------SGPQA---------------KDALKAALPA--PSPGALP-RRDSGPKAG
ISLEDS------SSIVVHPGEIAEAKTLPPHLGREGS---------------PRQLCM-K
PRTHRHGSASWGEG-------------LVTAQ-GGTLPGTKNSAREGSPGCSLTLPKARV
PSTPRDSIQLAKRHHSQPQVGPGCFNHVVSIEIGNLSALHPSRLPEVE-AR--AELREEP
ENMEMGEPPPGGKKEERES---------PQAPGAELEEVDLGNTPPTPPLHRFPSWES-R
IYAVAMAGMRLSDASPRMNAT--------CCASSPPALAFP-GPFSGLVYKNVTVPVYTA
LKGRATQISTVPFVDESSGSDDDCCSQASFRTSVPCSESRKTSGLGSPRAIKR-GVS-MS
SLSSEGDYAIPPDAYSLDSDYSEPEHKLQRTSSYS-A--EG--PGLAGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPGLLEEWIRALQSLLKV
QAVGPPALPRGGSKPTVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGHLPVRD
ARIEEVDRSCDSDEDYEA-GGSRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SATVGTAYEQLIGKLMDGE-GDPDSPLWRHPILCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLAHPELQSEIYCQLMKQTSG
RP--PQKCSLI-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1463)

ILLRNPFHHSSPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLHGSIKICDAISKWEQAVKELHSGKAE
GGTRVVKLMYKNRLYFRSQVKG

PF00373 // ENSGT00920000149052_1_Domain_4 (1463, 1624)

ETERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPSPPGPGSPPPAKVQHHLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADLLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQMFSKD-SSLVWIAVNEDGVSILDYSTMQVHVTYPYSSVMTFGGCRDDFM-
-LVIRSIPDQSSGKGHIEKLLFRMAAPKIAEATFIMASYMNHCSATV-NPRN--------
--NPPAAHRLWELDGQQFFASVPCAARGPTLL

------------------------------------------------------------
----------------------------------MAELKVDARASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSAG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPHGAAEQDSVPSEPGIQPTGQ
N----------SGSQA---------------EG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPSEDS------SSSTVHSGEMVEAKPLQPHLGREGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLTKRHHSQPQVGHGHFDRVVSIEIGAFSALHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNEERES---------PQALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRMSVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQNLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQFLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPRKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFQMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NLPGACQLWELDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAEFKVDTQASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEERAEKAETQVGVMEEKVKLSNLRNVDSTG
SLHRKYQELLKAMQSQVELISQLEAQLEKQKQMRAEEAKIVQKKAAKIKEWVALKLTELE
-MENQHLKSCNQHLVEQVGALQTALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVIPKGTPELESVPAESGAQPVGQ
D----------SGSQA---------------LD-LKVAIPA--PSLDAPKSSKGFLSQAR
NSTEDS------CSSTFHPEEVAETTVLQPHLESEHF---------------PSQLCV-K
PGASGCGSASCGEG-------------VVTAQ-ERVLPGIKTSAREGGPGSSLTLPKVRA
PSTPQDSIQVTKRHHSQPHVGPRRFEHVMNAESGALSALHPFGLSKLE-TY--ADFWEEP
EKMEMGELPPAGKEEERKS---------LKAPTTELEEVKLGNKPPTPPLHRFPSWES-R
IYAVATSGMQVSDVSPQSNAAGCA--------SSPPALVCP-GPFSGLTYKNVPVPVYTA
LKGKATQISSVPFLDESSGSDDDCSSQASFRMSVPCSECRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKMQRTSCYSTE---GQGLGTGTESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSSYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPNDVILKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLMADSPSLLEEWIRALQSLLKV
QATGPPALSQGGTKPAVKGWLTKVKHGHSKLVWCALIGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-AGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VVAGGS--SGKVGTAYEQLIGKLMDGE-GDPDSPLWRHPTLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTVLQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSHMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSQSGFALLTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRIVKLMYKNRLHFRSHVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAYQTNGEIVAGRFPVSKELALEMASLMA-
QIEYGHMEKPILPGPGGTPPAKAQHLLQQVLDRFYPRHYRHGAPPEQLRYVGCKVLWGVT
VERHQSHENILALDWHFFPPTQTRHLANMLATKWTSLQGCSLAEYTRTYLTVARKWPLFG
AKLFAAQPAQLSSKE-NTLVWIAVNEDGVSILDHHTMQVHVTYPYSSLTTFGGCRDDFM-
-LVIRSTPDQSSGKGHIDKLIFRMAAPKIAEATFIMASYMNHCSATV-NSPT--------
--YLPAAHLPRELDGQQFFASVSCATKGPILL

------------------------------------------------------------
----------------------------------MAELKVETQASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQDLEQRLLEAEQRAENAETQVGVMEEKVRLSSLQSMDSAG
SLHRKYQVLLKAVQGKNELISQLEAQLEEQKQMRAEEAKIVQEKAAKIKEWVTLKLAELE
-TENQHLKSCNQHLVEQVGALQDALV----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVAPQGAPEQDSVSSGPVPQTTGK
D----------SGPQA---------------QG-LKMAVPV--PSPGALR-SKDSVSEAG
SPLEDS------SSSVVRSGETAEGKTLQPHLETEGS---------------PHRLCA-K
PRIPRCGSASWSEG-------------LVTAQ-GGMPPGIKTCAREGVPGSSLTLPKVRA
PGTPRDSIQVAKRHHSQPQVGPGHFDHVVSIEIGAFSALHSSGLRALE-AR--AEFLEEP
EQMEMEEPPLARKKEERES---------RKAPGAELEEVELGKKPPTPPLHRFPSWES-R
IYAVATSGMQLSDVSPKSIAAYCA--------SSPPALASP-GPFSGLIYKNVTVPVYTA
LKGRATQISTVPLVDESSGSDDDCSSQASFRTSFPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWVRVLQSLLKV
QTTGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRSHEDKRPLGRLPVRD
ARIAEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPTLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHVLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQQLNQETGMRKSSHSGFALFTDDPFGRDLEHCLQGSVKICDAISKWEQALKELHAGKSE
GGTRVVKLIYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQASGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPVLPGHGGTPPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQVSSKE-NTLLWIAVNEDGVSILDHNTMQVHVTYPYSSVMTFGGCRDDFM-
-LVIKSIPDRSSGKGQIEKLIFRMAAPKIAEATFIMASYMNHCSANV-NPST--------
--NPPAARQLWDLDGRQFFASVPHATKGPTLL

------------------------------------------------------------
----------------------------------MSEIEVENGTCVNWQKRCLALETQLF
RFRLQASKIRKLLADK---MQELEQRLLEAEHRAEDAETQVGAMEEKIRLVSVKSMEPEG
NLHQKYQELLETIRGKEEIISQLQVQVEKQKLLRVQDAKTVQEKAAKIKEWVTMKLGELE
-MENRHLKNYNQHLLGQVRALQEALG----------------------------------
--------------------------------------------------------DLSM
------------------------------VLPGELLWSFQGKSKNS-VVSEISTYHESR
RGAVEGRPSGDNASQA---------------HSTLRATIS--FPSPGTQQ-DKDLTPKVG
NTLKGS--------GIVLCREISEAKAPQLSPMGT--------------------LKL--
-----QKSPYLGEV-------------LGGFQ-RGVPIKLRFPGKEGVLGSSMTLPKSRA
FRNPRDSIQLAKRRYSQPHLRTGHFNHMVSIKISALQASQDHSLPMKE-TDIDQKKRKES
EKMDTEEPTLDKIEVKGIELIS--RLNEENLERPSAGEVEMGKKPPTPPLHRFPSWES-R
IYAVASSGMQLSEVSPENDASSCA--------ASSTSLTSP-GSFYRLIYKNFHVPVYTT
LKGRATQISTMPFLDESSGSEDDCSSQASFQTSFTCMESRKTSVPGSPRAIKRG-VS-IS
SLSSESDYAIPPDAYSLDSDYSEPEYKVQRTSIYSID-----ELGSLGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
DSRVKTWKRRWFVLRHRQIMYYKSPSDVIRKPQGQVELNSHCH-----------------
------------------IVRREGAQTFQLISEKKTYYLTADSPNLLEEWIRVLQSLLKE
QTIGSPALPQSGAKPTVRGWLTKVKHGHSKLVWCSLIGKTFYYYRSHEDKYPLGCLPVRG
ARIEEVDRSCDSDEDYEAAGGMRRLLSSHSTLVIHPPEHSPTYLLIGSKHEKDTWLYHLT
VAAGSS--SAKVGTAYEQLIGKLMDGE-GDPGSPLWRHPMLCYSKDGLCASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSELYCQLIKQTSC
HP--PQKHSLL-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVKRTLKAGEREAKPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1463)

ILLRNPYHHSLPFSIPVHFVNGTYQVVGFDGSSTVDEF
LHRLNQETGMRKTSYSGFSLFTDDPSGKDLEHCLQGRVKICDAISKWEQSLRELHPGKSE
GSNRIVKLIYKNRLYFRHQVKG

PF00373 // ENSGT00920000149052_1_Domain_4 (1463, 1624)

ETEQERLLLAFQVSNEITAGRFPVNKELALEMAALMA-
QVEYGDLEKPNLPGPGGTAPAKAQHLLQLVLDRFYPRRYRYGAPSEQL------------
-----------------------RHLADTLASKWTTLQGCSSSECIRTYLTVARKWSLFG
AKLFAAQTTQLSTKG-NTLVWIAVNEDGISILDHNTMRIQATHPYSLVMTFGGYQDDFM-
-IVIRTVLDKSSGKGKIEKLIFQMALPKIAEVTFMMASYMNHCSTVSPSSTN--------
---TLYP---QEVDEKQFLASASHSSKGPTLI

-------------------------------------------------------ATQGR
RRRRPEGARVPGARRGRPRARWRAPWNNPEVDSIMAELKVEALASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQRLVEQVGSLQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPHGAAEQDSVPSEPGIQPMGQ
D----------SGSQA---------------QG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSTVHSGETVEAKPLQPHLGRESP---------------PHQPRM-K
LLTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVWA
PGTPRDSIQLTKRHHSQPQVGRGHFDHVVSIETGAFSALHPSGLPELE-SR--ARYREEP
EKMEMEELPPAGKNEERES---------PKALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATWGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSCCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLMADSPSLLEEWIRVLQSLLKV
QATGPPALSRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVH-
------------------------------------------------------------
--------------------------------SPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSELYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLRTGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1465)

ILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

DRERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKSSGKSHIEKLIFQMAAPKIAEATFIMASYMNHCTTTV-NPPT--------
--NPPGACQLWELDGRQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELAMENGSCMDWQKRCLALETQLF
KFRLQASKIRELLAEKAVKMQELEQRVIEAEQRAENAEKQVRVMEEKVKLDNMKTSESES
TLYRKYQELLGTVQGKDDLISRLEMQLEQQKQLRAEEAKIIQDKAAKIKEWVTFKLRELE
-LDNYHLKNCNQRLTEQIEALQDALQVQTDSWISCLGGGYCC-QGIFSPPFTCFSSEF--
-------LSSPL---AVYTDRMAAFLQS----------------------------YTDV
VPSPCVSIWHFEVPRTPLRSFQRQHSMERRKVPRTLLSSLLEKPAQNSFLLGMGVKQECQ
GRAKH-VPPTPTTILVDEASLAKEASKSLSSQNMLRVIPD---SSNWKPTVEKDAFCTVI
SDTSSGCPDPTLQDPTVESTSVLDALAFQSSLGRNQNSLSTLEQRASELGNSSDELSA-K
FRSHRLDSSSSGEISI-PYGCLPTAEPRLGLPSSITSTQPSFPGRECGLSNSMTLPKIRT
PSSPRDSIQLAKRHYSQPQPGAHRFHHITSIEIGTFQPITASTLCPAPVEETDIDGDDLL
EKMETEGCPVGEETGMGVETDQHPGSGKNECGNSEAGPLDRGGKPPTPPLHRFPSWES-R
IYAVAKSGMRLSEVALGTNSPSWI--------LNFPSYSNS-GPFTGLIYRNVTVPVYST
LKGKATQISNIPFLDESSGSDDDCSSHASIRTSNGGSEIRKSSTPGSPRAMKR-GVS-MS
SLSSESDYAIPPDAYSLDGDYSEPEHKLQRTSSYSTD------GGVCSEPM

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSQVKTWKRRWFVLRNGQIMYYKSPSDVIRKPQGQAELNSSCQ-----------------
------------------IIRGEGSQTFQLITEKRTYFLTADSPNILEEWIRVLQSILKV
QVTSSAALPQKDAKPTVKGWLTKVKHGHSKLVWCALIGKAFFYYRNNEDKCPLGHLYIRK
SKVEEVDRSCDSDEDYEATAG--GLLSSHYTLVIHPQDQSPTYLLIGTKHEKDTWLYHLT
VAAGSS--NAKVGTAYEQLIGKLLDAE-GDPQSPLWKHPMLCYSKDGLHTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAPSIDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLTHAELQNEIYCQLVKQTSC
RQ--PRNHSVI-QCWQLLALCAPLFLPQHHFLWYIKQHLQRHADPRIRSEIGKYAIYCQR
SVERTLHTGEREAKPSRMEIVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1465)

ILLRNPFHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEF
LQRLNQETGMRKLSHTGFSLFTDDPSGKDLEHCLQGTVKICDVISKWEQAFKELHPGKYE
GSTRIVKLTYKSRLYFRNQAKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

DRERLLLAFQISCEIANGRFPVNKELALEMVALMA-
QVEYGDSDRPVSSSPGGTPQSKMQHIVQQVLDKFYPKRYKQNITPEHL------------
-----------------------RRLADKLATKWMVLQGCSPLECIRIYLAVARKWPLFG
AKVFAAKPALPSLLE-DCPVWIAVNEDGISILDYNTMHLKLSYPYSSVLTFGGCRDDFM-
-IVVSQGKDRSSGKNSTEKLLFTMAAPKIVEVTLLIASYINYCALTPLLSPAPPSLSVIS
PLSTTPTKKLWETQSQCFFPSVPRTTKGPTLL

------------------------------------------------------------
----------------------------------MAEVKMEV-ASIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAEDAETQVSVMEEKIKLSSLKNVDSTG
SLHQKYQELLKALQSKDELISQLEAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-KENEHLKAHNQQLVEQVEALQDALE----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEKLLVVPEGIPEGNPVPSGPRAQPVEQ
D----------SNPHT---------------QT-SKVVVPA--PALSTLQ-NKDSASEAK
SLEDSNF-------SMVYSGEIAEAKTLKSHLQREGS---------------PSQLFM-K
PGSPRHGSVSYRDD-------------LLIAQ-GGTFPGTKISTREGGPGSSLTLPKVRA
PSNSRDSFQVTKRHHSQPQVGPGHCNHVVSIKIGALSALPSSGFSKSE-VR--AKAREEA
EKMEMEEAPPSGKQEERES---------PKPPRAELEEGELENKPPTPPLHRFPSWES-R
IYAMATSGMQLSSDASSRSDAACC-------ASGPPALAFP-GAFSGLIYKNVTVPVYTA
LKGKATQISSVPFVDESSGSDDDCGSQASFRMSLPCSEYRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPNDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISENKTYYLTAESPSLLEEWIRVLQSLLKV
QVTGPPALRLGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVQD
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVINPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTVYEQLIGKLMDGE-GDPDSPLWRHPMLCYSRDGLCTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQRLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1464)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGE

PF00373 // ENSGT00920000149052_1_Domain_4 (1464, 1624)

TERERLLLAFQTSGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPILPGPGGTPPAKSQHLLQQVLDRFYPKRYRIGAPPEQL------------
-----------------------RHLADTMATKWAALQGCSPAECIRIYLTVARKWPLFG
AKLFAAQPAQL-SSKESTLVWIAVNEDGVSILDHHTMQVNINYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKSHIDKFIFQMPAPKITEATFMIASYMNHCSATV-NLST--------
--KLPATRQPRDLDGQ-LFASVSCTKGSALL-

------------------------------------------------------------
------------------------------------------------------------
------------------KMQELEQRVIEAEQRAEDAEKQVRVMEEKIKLADVKTGEFDS
TLQKKYQELMCTMQGKEDLINKLETQLAKQKQLRTEEAKIVQEKAAKIKEWVTFKLRELE
-LENYHLKNCNQRLMEQIEALQDTLQGKCVQLALQPSN----------------HH---K
SGSWHSW----------------------QAVELLCSVVG-------SIFKMG-------
--------------------------------------------------------ITCL
PALTLD------------------------------------------------F-----
-----------------------------------FSHQQSTIQLGLDSTRFSDDLSA-R
FHSHQLDSSSSAEIMSMLEGHLQTAEPPLVVSTSAVTAHSFFPGRECSLGSSMTFPKIRA
PNTPRDSIQLAKRHHSQPQSGANSFHRVMHLETSTFQPITDPPVGCGHVEETDIDDDGVM
EKMETECGLLRGETGTCEG---------IEAVSSESGTLDPGCKPPTPPLHRFPSWES-R
IYAVAKSGMRLSEVAMGNDTSSCF--------SNF-SCSTS-GPFTYLIYRNVTVPVYTT
LKGKATQISNVPFLDESSGSDDDCGSHASFRTSTAGCETRKASMPGSPRAVKR-GVS-VS
SLSSESDYAIPPDAYSLDGDYSEPEHKLQRTSSYSTD------GGICSEPM

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSQVKAWKRRWFVLRNRQIMYYKSPSDVIRKPQGQLELNSSCQ-----------------
------------------IVRGEGSQTFQLVTEKRTYFLTADSPNILEEWIHVLQSILRV
QVSSPVGVPHSDAKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRNHEDKCPLGHLPLRD
SKVEEVDRSCDSDEDYESTGG--GLLSSHCTLAIHPQDQSPTYLLIRTKQEKNTWLYHLT
VAAGSS--NATVGTSYEQLIGKLLDAD-GDPNSPLWKHPMLCYSKDGLHTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEASSIDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLTHTELQNEIYCQLVKQTSC
RQ--PQNHSLI-QCWQLLALCAPLFLPQHHFLWYIKQHLQRHADPR--SEIGKYAIYCQR
SVARTVQAGEREAKPSRMEIVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1465)

ILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEF
IQRLNQETGMRKPSHMGFSLFTDDPSGRNLEHCLPGNMKICDVISKWEQALKELHPGKYE
GGTRIVKLTYKNRLYFRSQAKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

DRERLLLAFQVSNEIASGRFPVNKELALEMVALMA-
QVEYGDLDRPGSSSPGGTSQLKMQHLLHQVLDKFYPKHYKQNITPEQL------------
-----------------------RQLTDRLATKWMVLQGCSPPECIRIYLTVARKWPLFG
TKIFAAKPILPSSLD-DCPVWIAVNEDGISILDYSTMHLKVSYSYSSVLTFGGCRDDFM-
-IVVSKMKERSSGKNSTEKLLFTMAIPKIVEATLLIASYINYRSTPSLLS----------
---KTPAKKPWETENRCFFPSVPRSTKGPTLL

------------------------------------------------------------
----------------------------------MAEPKVETQTSMDWQKRYLALETQLV
RFRLQASKIRELLSDK---MQELEQRLQEAEQRAENSETQVSVMEEKVKLSNLKNVGSAG
SLHRKYQELLKAVQGKDERIGQLEAQLEKQKQMRAEEAKIVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQRLVEQVAALQEALE----------------------------------
--------------------------------------------------------ALQM
------------------------------ALSENLLVAPQEIPEQDSVPAGPGAQLMGQ
D----------SGAQA---------------QDPLKAALP-----------SEDSVPEVR
SATEEF------GSIVVRPGGLSEAKTLPSRLGREGS---------------PGQLCM-Q
TCTPGHALSSWDEG-------------LATAQ-AGSLPGTKTSAREGGPGCSLTLPKVRD
PSAPYDSVQLAKRHHSQPPVGPERSNHVGSAEIGTLAALPHSGLPKVA-AP--AELEEEP
EKMEMEEPPPAVRKEERES---------QKVSTAELEEVDSGGKPPTPPLHRFPSWES-R
IYAVATSGMCLSDVPPRSSATCF--------GSRPPSISSP-GPFSGLVYKNCTVPVYTV
LKGRVTQISTVPFVDESSGSDDDCSSQASFQSSVPCSEPRKTSGLGSPRAIKRGQVSPMS
SLSSEGDYA-PPDACSLDSDYSEP-HKLQRTSSYS-T--EGTNPGRSEES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDIIRKPQGQVELNSRCQ-----------------
------------------IVREEGAQTFQLISEKKTYYLTADSPCLLEEWIRVLQRLL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

KV
QALGPPALPQGGTK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PTVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGHLPVQD
AHVEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIQPPEHSPTYLLIGTKHEKDTWLYHLT
VAT

ENSGT00920000149052_1_Linker_1_3 (1144, 1227)

GGS--SAKVGTAYEQLIGKLMDAE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKC--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLVQRALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLT-QCWQLLALCAPLFLPQHHFLWYIKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRTEVMSILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRNPSHSGFALFTDDPSGRAVEHCLQGRVKLCDAISKWEQALKELHSRKSK
GGTRDVRLMYKSRLYFRGQVKGETERERLLLAFQTSGEIVAGRFPVNKELALEMAALMA-
QVEFGDLERHLSPSPGGTPPSKAQHHLQQVLDRFYPRRYRYGTPTEQL------------
-----------------------RHLVDQLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPVPLSSKE-NPLVWIAVNEDGVSILDHNTMQVRVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKGHIEKLTFRMAAPKIAEATLLMASYMSHCSITV-NTPT--------
--KPPAAHQPWELAGQQLFASLPRAAKGPTLL

------------------------------------------------------------
----------------------------------MAELKVEAPASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQRLVEQVGSLQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPHGAAEQDSVPSEPGIQPMGQ
D----------SGSQA---------------QG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSTVHSGETVEAKPLQPHLGRESP---------------PHQPCM-K
LLTFRCSSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNEERES---------PKALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALVSP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFQISVPSSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSL

ENSGT00920000149052_1_Linker_0_1 (1018, 1038)

LKV
QATGPPALLRGGTKPTV

PF00169 // ENSGT00920000149052_1_Domain_1 (1038, 1140)

KGWLTKVKHGHSKVVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPTEHSPTYLLIGTKHEKDTWLYHL

ENSGT00920000149052_1_Linker_1_3 (1140, 1231)

T
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLRTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVAKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAVLMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHTTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCTTTV-NPPT--------
--NPPGACQLWELDGRQFFSSVSCATKGPTLL

-------------------------------------------------------STQGQ
XXXXXXXXXXXXXXXXXXXXXXXA-PWNPEVASIMAELKVETRTSVDWQKRCLALESQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAEDAETQVGVMEEKVKLSNLKNVDSAG
SLHRKYQELLNAMQGKDELIGRLEAQLEKQKKMRTEEAKIVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQHLVEQVGALQRALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APLGKLLVAPQGTTEQDCVPAGPGAQPVGQ
D----------GGAQA---------------QGALKAAMPV--PSPGALQ-SKDSVPKAG
SPLEDS------SSSMVHPGEISEAETLPLHLGGQGS---------------PGQLCL-K
PCTPRHGLASWGEG-------------LVTAQ-GGTLPRTKTSAREGGPGCSLTLPKVRA
PSTHRDSIQLAKRHHSQPQAGPAHFDHVVSIETGTLSALHSSSLPKVE-AG--PELREEP
EKMEMDEQSPAGK----------------------MEEVDLGNKPPTPPLHRFPSWES-R
IYAVATSGMRLSEVSARSNAT--------CCASSPPALASP-GPFSGLVCKNITVPVYTA
LKGKAMQISTVPFVDESSGSDDDCSSQASFRTSVPCSESRKTSGLGSPRAIKR-GVS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLLXXXXXXXX--XX--XXXXXES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

KV
QAIGPPALTQGGAK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PAVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGRLPVQD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAA

ENSGT00920000149052_1_Linker_1_3 (1144, 1227)

GGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCXXXXXXXXXXXXXXXXXX
XTKAVKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLVHPELQSELYCQLMKQTSC
RP--PHKCSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARSRE--VVSLL-----PSHSSFSIPXXXXXXXXXVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHSGKSE
GGTRVVKLMYKNRLYFRSQVKGETERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPILPGPGGTPSAKALHHLQQVLDRFYPRRYRHGAPLEQL------------
------------------------HLADQLTTKWAALQGCSSPECIRIYLTVARKWPLFG
AKLFAAQPAQPSSKE-NTLVWIAVNEDGVSILDHNTMQVHVTYPYSSVMTFGGCRDDFM-
-LVIRSTSDQSSGKGHIEKLIFRMAAPKIAEVTFIMASYMNHCSTTV-DPPP--------
--NPPAACQPWELDGRQFFASVPCAAKGPTLL

-------------------------------------------------------SKQGQ
RRT--RGGARVRARQESPRARGRD-PWTPEVDSIMAELKVETRTSMDWQKRCLSLETQLF
RFRQQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSAD
SLHRKYQELLKTLQDKDKLIHQLEAQLEKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-------XX------------XXXXX----------------------------------
-----XXXXXXXXXXXXX---------XXX------------------------XXXLQM
------------------------------APSGDLLVNHQGTPEQESPPSEPGPQPVWQ
D----------SVSKL---------------QVALQAVMPA--PSPGSLH-SKDCGFKAD
GPSEDS------SSSLICPGEI-EAKTIPPHLGREGS---------------PGQLCV-K
PPVPRHGSASWGEG-------------LAPGQ-GGTLPGTKACARDGRPGSSLTLPKVWA
PGTRQDSIRLAKRHHSQPQVGPGGFDFRVIVEAGTLPAFHPSSLPKVE-AP--AELREEP
EKMEMEEPSPAGKRAERES---------SKAPGPELE-VDLEINPPTPPLHRFPSWXX-X
XXXXXXXXXXXXXXX--------XXXXXXXXXSSPPALGSPGGPFSGLVYKNLTVPVYTS
LKGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX-X-
----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKHRWFVLRQGQIMYYKSPXXXXXXXXXXXXXXXXXX-----------------
------------------XXXXXXXXXXXLISEKKTYYLTADSPNLLEEWIRILQSLVKV
QAMRPPALPQGGAKPTVKGWLTKVKHGHSKLVWCALVGRTFYYYRSYED-----------
---------------------------------------------------KDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX--XXXXXXX-XCCQL--TLAPLFLPQHHVLLYIKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYQVVGFVGSSTVDEF
LQRLNQETGMRKTSHSGFALFMDDPSGRDLEHCLQGSVKICDAISKWEQALKELHSGKSE
GGSRVVKLLYKNRLYFRSQVKGETERERLLLASQTSGEIVLGRFPVNKELALEMAALMA-
QVEYGDLERPNPPGPGGTPPTKAQHHVQQVLDRFYPRRYRHGAPIEQL------------
-----------------------RLLTDLLTTKWAALQGCSPPECVRIFLTVARKWTFFG
AKLFAAQTAQLSSK--NILVWIAVNEDGVSILDHNTMQVHVTYPYSSVMTFGGCRDDFM-
-LVIRSVPDQNSGKGHIEKLIFRMAAPKIAEATFVMASYMNHCSAAV-NKPS--------
--HPPAAHQLWELDGRQFFAPIPSAANRPALL

------------------------------------------------------------
----------------------------------MAELKVESRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVNSTG
SLHRKYQELLKVMQGKDELISHLEAQLEKQKQLRAEEAKIVQEKAAKIKEWVTLKLSELE
-MENQHLKNCNQRLVEQVGALQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------TPSGKLLVAPQEAPEENPVPSEPGAQPVAQ
D----------SGSQV---------------QA-LKVALPG--PCLGALQ-SKVSVPEAR
SPVEDS------SSSMVHPEEI-EAKTLPPHLGKEGS---------------PTQLGV-T
PGSTRCGSASWGES-------------LVTARCRGILFGTKTSAREGGPGSSLTLPKARA
SSAPWNSIQVAKRHHSQPQVGPGHFDHVVNIEVGALAALHPSVLSKLK-PP--AELREEP
EKMEMEESPPAGKE-EGEN---------LKAPRPELEKEELEKKPPTPPLHRFPSWES-R
IYAVATSGMQLSDVSSRSHVACCA--------SSPPALASP-VSFSGLVYKNVTVPVYTA
LKGRAMQISNVPFADDSSGSDDDCSSQASFRISVPCSECRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----ESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQNLLKV
QATGPPALPQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGRLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLCTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQSGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRVVKLIYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAFQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPTLPGPGSTPPAKTQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLIDMLTTKWAALQGCSPPECIRIYLTVARKWPLFG
AKLFAAQPAKLSSKE-NTLVWIAVNEDGVSILDHHTMQVHITYPYSSVTTFGGYRDDFM-
-LVIRTIPDQGSGKAHIEKLIFRMTAPKIAETTFIMASYMNHCSTTV-NPPA--------
--NSPAARQPWELDGRQFFASVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELKVDARASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSAG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPHGAAEQDSVPSEPGIQPTGQ
N----------SGSQA---------------EG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPSEDS------SSSTVHSGEMVEAKPLQPHLGREGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLTKRHHSQPQVGHGHFDRVVSIEIGAFSALHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNEERES---------PQALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRMSVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQNLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQFLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFQMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NLPGACQLWELDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------PEVDSIMAELKVESRTSVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGMMEEKVKLSSLKNVDSAG
SLHRKYQELLKAVQGKDELIGQLEAQLEKQKQMRAEEAKIVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQHLVEQVGALQDALG----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLRVAPQGALEEDSVPSGLGTQLMGQ
D----------SGPQA---------------QGALKVAIPA--PSPGTLQ-NKDSVAKTG
SLFEDS------SASMVHPGEISEAKTLPPRLGREGS---------------PGQLCV-K
PHTPRHGLASWGEG-------------LVTAQ-GGMLPGTKTSARGGGPGSSLTLPKVRA
PSTPRDSIQLAKRHHSQPQAGPGHFNQVVSIEIGTLSALHPSSLPEVQ-AR--AELREEP
EKMEMEEQPPAGKKEDRES---------PRAPRAELEEVDLGNKPPTPPLHRFPSWES-R
IYAVATSGMRLSDVSPRNNVT--------CCTSSPPALASP-GPFSGLVYKNVTVPVYTA
LKGRATQISTVPFVDESSGSDDDCSSQASFRTSLPCSESRKTSGLGSPRAIKR-GVS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYS-M--DG--LGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLICEKKTYYLTADSPSLLEEWIRVLQSLLKV
QAIGPPALPQAGTKPTVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGRLPVRD
ARIEEVDRSGDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGP--SAKVGTAYEQLIGKLMDGE-GDPDSPLWKHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKHSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSVKICDAISRWEQALKELHSGKSE
GGTRVVKLMYKNRLYFRSQVKGETERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPIPPGPGGTPPAKAQHHLQQVLDRFYPRRYRHEAPPEQL------------
-----------------------RHLADLLTTKWAALQG-SPPEVIRIFLTVAGKWLSLG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVMTFGGCRDDFM-
-LVIRSNPDHSSGKGHIEKLIFRMAAPKIAEATFIMASYMNHCSATV-NPPT--------
--SPPAARQPWELDGRQFFPSVPRAAKGPTLL

------------------------------------------------------------
----------------------------------MAELKVDVRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSPG
SLYQKYQELLKAMQGKDELIRQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQCLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPHGAAEQDSVPSEPGIQPVGQ
D----------SGSQA---------------QG-LMAAVLA--PSSGALQ-SKDSVSEAA
SPSEDS------SSSTVHSGEVIEAKPLQPYLGREGC---------------PRQPCM-K
LQTFRCGSASWGEH-------------LVTAQ-RGTLPGTKTSAREGGPGSSLTLPKVRA
PNTPRDSIQLAKRHHSQPQVGHGHFDHVVSIEIGTFSALHPSGLPELE-AR--AGYRDEP
EKMEMEEPPPAGKKEERES---------PKALGAEPEEVEPGSKPPTPPLHQLPPWES-R
IYAVATSGMRLSDASPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPGSESRKTSGLGSPRAFKRG-VS-MS
SLSSEGDYAIPPDACSLDGDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRMKTWKRRWFVLRQGHIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWVRVLQSLLKV
QPTGPPALPQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQAGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRMNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAQKELHPRKPE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREILAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRTIPDQSSGKSHIEKLIFRMAAAKIAEATFIMASYMNHCSTTV-NPPT--------
--HPPGARQLWELDGRQFFASVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELKVEAPASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAKLE
-MENQHLKSHNQRLVEQVGSLQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPYGAAEQDSVPSEPGIQPMGQ
D----------SGSQA---------------QG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSTVHSGETVEAKPLQPHLGRESP---------------PHQPCM-K
LLTFRCSSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSGLPELE-SR--ARSREEP
EKMEMEEPPPAGKNEERES---------PKALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDMSPRSNTACCA--------SSPPALVSP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALLRGGTKPTVKGWLTKVKHGHSKVVWCALVGKIFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPTEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLRTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYHVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPINKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHGAPAEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCTTTV-NPPT--------
--NPPGACQLWELDGRQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELTEENGSCMDWQKRCLALESQLF
KFRLQASKIRELLAEKALKMQELEQRVIEAEQRAEDAEKQVRVMGEEIKLANMKTSESNS
TLYRKYQELMGTVQRKEDVISRLEIQLAKQKQLRTEEAKIIQEKAAKIKEWVTFKLKELE
-LENYHLKNCNQRLTEQIEALQDTLQAWLLLEVCCPCSNGTE-E----------RLNLQR
GWLWCSFLSLVLENKEHCVDRCISLCLSVRVSPLACPDMAATEIQLQQITLARNIFYDMT
SIPPLESLWSCN-------------S----LKPRASQVSYPEKIDQKSRLLAPAFRQACQ
TGLTKHVLSTTNIVLASDNFTEDGEDKSLLSQNTLKLLAD---PSSWNLSTEKDTFSAIS
SEHRLGCSDPRSLDPPTEPTKLLGALTFQSSLESNHS--------------TPDDLSA-R
FHSHCLDSSFS--------GRLQTAEPPLVVSASAVTACSTCPERERGLSTSMTFPKIRT
PSIPRDSIQLAKRHYSQPQSGTSSSCRVMSFEASTFQPIKDSPVYHRPVEETDIDDDAVL
EKMETEAGLVREEAGMCEI--NHLPTEQREVVSSKAGVLEPGGKPPTPPLHRFPSWFCCH
VLNISXSGMRMSEVATVNDTPSCF--------SNF-SYSAS-GPFTCLIYRNITVPVYTT
LKGKATQISNVPFLDESSGSDDDCGSRASFRNSAAESENRKASVPGSPRATKR-GVS-MS
SVSSESDYAVPPDAYSLDGDYSEPEHKLQRTSSYSTD------GGICTEP

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

IEKSGYLLKM
GSQVKMWKRRWFVLRNRQIMYYKSPSDVIRKPQGQMELNSSCQ-----------------
------------------IVRGEGSQTFQLMTEKRTYFLTADSPNILEEWIHVLQSIL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

RV
QVTSPVGVPHSDAK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PTVKGWLTKVKHGHSKLVWCALIGKTFYYYRNHEDKCPLGHLPMRE
SKVEEVDRSCDSDEDYETTGG--GLLSSHCTLVIHPQDQSPTYLLIRTKQEKDTWLYHLT
VAA

ENSGT00920000149052_1_Linker_1_3 (1144, 1227)

GSR--NATVGTSYEQLIGKLLDAE-GDPNSPLWKHPMLCYSKDGLHMSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEASSI

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLTHTELQNEIFCQLVKQTNC
RQ--PQNHSVI-QCWQLLALCAPLFLPQHHFLWYVKQHLQRHADPR--SEIGKYAIYCQR
SVDRTVQTGEREAKPSRMEIVSILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEF
IHRLNQETGMRKPSHMGFSLFTDDPSGRDLEHCLQGNMKICDVISKWEQALKELHPGKYE
GGTRIVKLTYKNRLYFRSQAKGETDRERLLLAFQVSDEIASGRFPVNKELALEMVALMAQ
QVEYGDLDRTASSSPGGTSHSKMQHLLHQVLDKFYPKRYKKNIAPELL------------
-----------------------KQLVDRLATKWMALQGCSPPECVRIYLTVARKWPLFG
TKLFAAKPILPSSLE-DCPVWIAVNEDGISVLDYNTMHLKFSYSYSSVLTFGGCRDDFM-
-IVVSQIKERSSGKNSTEKLLFTMAIPKIVEATLLIATYINSRLTTPLLPSAQPSR----
--STTPANRLWETESRCFFPSMPRSTKGPTLL

------------------------------------------------------------
-----------------------D-PWNPEVGSIMAELKVEMPACVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLE
-MENQHLKSCNQCLVDKVGALQNALE----------------------------------
--------------------------------------------------------ALRM
------------------------------APSGKLLVAPQETPDQDFLTSEPGTQPTGQ
A----------SSSQT---------------QGTLKTAVPA--PSPGALQ-DKESLPEAG
SPLEDS------SSSLVRPWEIAEARTPPPYLGRESS---------------PGPVCV-K
PHTPGCGSASWGEG-------------LVSAR-GTLP-----------------------
------------------------------------------------------------
-------------------------------------------------------PES-R
IYAVATSGMQLSDASPRSNVSCCXXX-XXXXXXXXXX--------XXXXXXXXXXXXXXX
XXXRAMQISNVPFVDESSGSDDDCSSQASFRTSVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSESDYAIPPDACSLDSDYSEPEHKLQRTSSYS-T--DG--LGLGRES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVVRQGQIMYYKSPNDVIRKPQGQVELNSRCQ-----------------
------------------LVQGEGAQTFQLISEKKTYYLMADSPSLLEEWIRVLQSLLKV
QATGPPALSQGGSKPTVKGWLTNVKHGHSKLVWCALIGKTFYYYRSHEDKRPLGCVPMQD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVICPPEHSPTYLLIGTKHEKDTWLYHLT
VATGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPLEATSV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLVHPELQSEIYCQLMKQTSF
HP--PQXXXXX-XCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHNGFSLFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPRKSE
GGTRIVKLMYKNRLYFRSQVKGETERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPNLPGPEGTPPAKAQHLLQQVLDKFYPRRYRHGVPPDQL------------
-----------------------RHLADMLTTKWAALQGCSLPECIRIYLTVARKWPFFG
AKLFAAQXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXQVHVTYPYSSVMTFGGCQDDFM-
-LVIRSIPDQSSGKSRIEKLIFRMAAPKIAEASFIMVSYMNHCSAT--------------
--------------------------------

------------------------------------------------------------
----------------------------------MAELQVGTQASVDWQKRCLTLETQLV
RFRLQASKIRELLADK---VSPESGELPGTSGSAGRARVTVGVMEEKVKLSNLRNVDSAG
SLHRKYQELLKAMQGKVELISQLEAQLEKQKQMRAEEAKVVQKKAAKIKEWVALKLTEVS
-EM-------------LIGLAFAPTS----------------------------------
--------------------------------------------------------ALQM
------------------------------GPPGKLPVIPKGAQEQESVPAEVGAQPVGQ
D----------GGSQA---------------PD-LKAAVPI--PSLDASE-SKGFLSEAR
SPVEDT------SSSALRPGEVAKAKVLQPHLESEHF---------------PSQLCM-K
PGAPRRGSASCGDS-------------LAPAQ-ERLLLGIKTSAREGGPGSSLTLPKVRV
PSSPQDSIQMTKRHHSQPYVGPRHSEHVVNVEVGALSTVHTSGLSKLE-TC--ADFREEP
EKMETGELPPAGKEEERGS---------LKAASTKLEDVRLGSKPPTPPLHRFPSWES-R
IYAVATSGMQVSDVSPRSSAACCG--------ESETERLE--GSGGPLVAGWVSMEEETA
IARKATQISSVPFMDESSGSDDDCSSQASFRMSVPCSECRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKMQRTSCYS-------------ESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPNDVILKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLMADSPSVLEEWIRALQSLLKV
QATGPPALLQGGTKPAVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVGD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAQVGTAYEQLIGKLMDGEGGDPDSPLWKHPILCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTVLQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVRQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSHMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPCGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRIVKLMYKNRLHFRSQIKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLTYQTNGEIVAGRFPVSKELALEMAGLMA-
QIEYGDMEKPILPGPGGTHPAKAQHLLQQVLDRFYPRHYRLGAPPEQL------------
-----------------------RHLTSMLATRWASLQGRSLAEYTRTYLTVARKWPLFG
AKLFAAQVSASKR---------------------------------STRHLQECPNRFFP
EPVLQSIPDQSSGKGHIDKLIFRMAAPKIAEATFIMASYMNHCSVPA-SSPT--------
--SLPAARPLRELDGRQFLAPVSCAAKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVEV-ASIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSNLKSVDSTG
TLHQKYQELLKAVQGKDELISQLQAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-MENQQLKTCNQQLVEQVAALQDALE----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEELLVVPEGTPERDPVPSGPSDQPVEQ
D----------SNPHT---------------QI-LKVAVPT--PSLGTLQ-SRDSLSEAR
SLEDLRF-------SVVHPGETAEAKTLQSHLQKEGS---------------PSQLCM-K
SGSPKHGSASYRES-------------LVTAQ-GGTFPGTKISVREGGPGSSLTLPKVRA
PSIPRDSFQVAKRHHSQPQVGPGHCDHVVSIEIGALSALHSPGSSKSE-AR--AKVREEA
EKMEMEALPLSGKLEERAS---------LKSRRGELEDVELENKPPTPPLHRFPSWES-R
IYAMATSGMQLSEVSSRRSNAACY-------ASGPPALAFP-GAFSGLVYKNVTVPVYTA
LKGKATQISNVPFVDESSGSDDDCGSQASFRMSIPCSEYRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEEAQTFQLISGNKTYYLTAESPSLLEEWIRVLQSLLKV
QVTGPPALHQAGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVQD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTVYEQLIGKLMDGE-GNPDSPLWRHPMLCYSQEGLCTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQISC
RP--PQKCSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYAIYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAFQTSGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPTLPGPGGTPLAKAQHLLQQVLDRFYPRRYRNGAPPEQL------------
-----------------------RHLADMMATKWAALQGCSPPECIRIYLTVARKWPLFG
AKLFAAQPAQ-LSSKENTVVWIAVNEDGVSILDHRTMQVNVTYPYSSVTTFGGCRDDFM-
-LVIRSTPDQSSGKTRIDKLTFRMPAPKITETTLTMASYMNHCSATV-NLSA--------
--KLPAARQPRDLDGQ-FFASVSCTKGSALL-

------------------------------------------------------------
----------------------------------MAELKVDVRASVDWQKRCVALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVSVMEEKVKLSNLKNVDSPG
SLHRKYQELLKALQGKDELIRQLEAQLEKQKQMRAEETKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQCLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSQKLLVPPHGAAEQDSVPSEPGIQPVGQ
D----------SGSQA---------------QG-LKAAVLA--PSPAALQ-SKDSVSEAA
SPLEDS------SSSTVHSGKLIEAKPLQPHLEREGS---------------PRQPCM-K
LQTFRCGSASWGEH-------------LITAQ-KGMLPGTKTSAREGGPGSSLTLPKVRA
PNTPRDSIQLAKRHHSQPQVGHGHFDHVMSIEIGTFSALHPSGLPELE-AR--ARYRDEP
EKMEMEEPPPAGKKEERES---------PKALGAEPEEVEPGNKPPTPPLHQLPPWES-R
IYAVATSGMRLSDVSPRTNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRAAQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAFKRG-VS-MS
SLSSEGDYAIPPDACSLDGDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRMKTWKRRWFVLRQGQIMYYKSPSDVIRNPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSL

ENSGT00920000149052_1_Linker_0_1 (1018, 1038)

LKV
QATGPPALPQGGTKPTV

PF00169 // ENSGT00920000149052_1_Domain_1 (1038, 1140)

KGWLTKVKHGHSKLVWCALVGKSFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHL

ENSGT00920000149052_1_Linker_1_3 (1140, 1231)

T
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQAGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRMNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQTQKELHPRKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREILAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGVPPEQL------------
-----------------------RHLADMLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKSHIEKLIFRMAAAKIAEATFIMASYMNHCSTTV-NPPT--------
--HPPGARQLWELDGRQFFASVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELKVDARASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---VSPSE-------RGAASPHTEVGVMEEKVKLSNLKNVDSAG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTIQEKATKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSWKLLVPPHGAAEQDSVPSEPGIQPMGQ
N----------SGSQA---------------QG-LKAAVLA--PSPDALQ-SKDSVSEAA
SPLEDS------SSSTVHSGEMVEAKPLQPHLGREGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLAKRHHSQPQVGRGHFDRVVSIEIGAFSALHPSGLPELE-SR--ARYLEEP
EKMEMEEPPPAGKNEERES---------PKALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPLGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NPPGACQLWEMDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------VGVMEEKIKLVNVNSIEPEN
NLHAKYQELLETIRGKEELISQLQAQVEKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXLE
-MENRCLKSYNQRLVGQVKALQEALR----------------------------------
--------------------------------------------------------DLSM
------------------------------VLPRELLWSFQGKPKKNSVVSEIGTHREGQ
D----------SASQP---------------QSALRAIIS--LPSPGTQK-DKDLIHETG
NTLKSS--------GRVICREIPEAMAAQFSPG----------------------YEL--
-----QKSAYLGEI-------------LGSFQ-RGVPIKLRFPAKEGVLGSSMTLPKVRA
FRNPRDSIQLAKRRYSQPQLRTGCFNPMVSIEISTLQTSQTHTHPERE-TS--TRKRKES
AKMDTEEPPSVRKKSK--AVSS--RLDKEELEKPIASEVETGNKPPTPPLHQFPSWES-R
IYAVASSGMQLSEVSPGNDASSCV--------SSSTALTSP-GSFSKLFYKNFHVPVYTT
LKGRATQISTMPFRDESSGSDDDCSSQASFQTSTTCIESRKASVPGSPRAIKRG-VS-IS
SLSSESDYAIPPDAYSLDSDYSEPEYKVQKTSVYSID-----GCGSYGES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
DSRVKTWKRRWFVLRHRQIMYYKSPSDVIRKPQGQVDLNSXXX-----------------
------------------XXXXXXXXXXXLISEKKTYYLTADSPNLLEEWIRVLQSLLKV
QAIGSPVLPQRGAKPIVRGWLTKVKHGHSKLVWCSLIGKTFYYYRSHEDKXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXX--XXXXXXXXXXXXXXXXXXX-XXXXSPLWRHPMLNYSKDGLCSSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLVHPELQSELYCQLIKQTSC
HP--PQGHSLL-QCWQLLALCAPLFLPQHHFLWYIKQQLQRHADPR--SETGQYATYCQR
AVERTLEAGEREAKPSRMEVVSILLRNPYHHSLPFSIPVHFVNGTYQVVGFDGSSTVDEF
LHQLNQEIGMRKTSHSGFSLFTDDPSGKDLEHYLQGSIKICDAISKWEQSLRELHPRKSE
GSNRIVKLIYKNRLYFRHQIKGETEQERLLLAFQVSNEITAGRFPVNKELALEMAALMA-
QVEYGDLEKPNLPGPMGTAPAKAQYLLQLVLDRFYPRRYRYGVPSEQL------------
-----------------------RYLADTLASKWTTLQGCSSTECIRIYLTVARKWSLFG
AKLFAAQTTQLSTKG-NTLVWIAVNEDGVSILEHNTMQVQATHPYSLVMTFGGYQDDFM-
-LVIRSGPDKSCGKGNTEKLIFQLALPKITELTFMMASYMNHCSTFSTSSPN--------
---IPPIGHLQEMDGKQFLASASHSTKGPTLL

------------------------------------------------------------
----------------------------------MAGLQVDTQASVDWQKRCLTLETQLL
RFRLQAGKIRELLADK---MQELEQRLLEAEERAEKAETQVGVMEEKVKLCSLRNVDSAG
SLHRKYQELLKAMQAKVELIGQLEAQLEKQKQMRAEEAKSVQKKAAKIKEWVALKLTELE
-MENQHLKSCNQHLMEQVGTLQAALE----------------------------------
--------------------------------------------------------AQQV
------------------------------EPPGRLLAAPEGASEPESTPAEPGTQSVGP
D----------NGSQA---------------LD-LRVVTPA--PSLDAPE-GKGFLSEAS
SPAEGS------NSRPFYPEERAEAKVLLPHVEHEHF---------------PSQLCP-K
PGAPRPGSASWGQG-------------LVTAQ-ERVLSGIKASSREGGPGSSLTLPKLRA
PNLPQDSVQLTKRHHSQPHIGPRRCEDVVGVDTGALSTLRPSGLSKPE-TC--ADFREEP
EKMEMGELPAARKEEEQES---------LMAPSTQLAEGKLGNKPPPPPLHRFPSWES-R
IYAVATSGMQVSDVCPRSSAACSA--------ASPPALVCP-GPFSGLVYKKVTVPVYTA
LKGKATQISSMPFGDESSGSEDDCSSLVSFRVSVPCSECRKTSSLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKMQRTSCYSGG-----------DSL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQMMYYKSPNDVILKPQGQVDLNSHCQ-----------------
------------------IVCGEGAQTFQLISEKKTYYLMAESPSLLEEWIWVLQSL

ENSGT00920000149052_1_Linker_0_1 (1018, 1036)

LKV
QAMGPPALLQEGAKP

PF00169 // ENSGT00920000149052_1_Domain_1 (1036, 1140)

VVKGWLTKVKHGHSKLVWCALVGKTFYYYRSPEDKRPLGCLPVQD
ARIGEVDEDCEADEDCEA-AAG-RWPSSPCTLVIQPPGRSPTYLLLSSKQEKDTWLYHL

ENSGT00920000149052_1_Linker_1_3 (1140, 1231)

T
VAAGGS--SVTVGTAYEQLIGKLMDGEGGDPDSPLWKHPILCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTVLQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYALM-QCWQLLALCAPLFLPQHHFLWYIKQQLQRHADPS--NETGQYATYCQR
AVERTLQTGEREARPSHMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRIVKLTYKNRLHFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAYQTNGEIVAGRFPVSKELALEMAGLMA-
QIEYGDMEKPVLPGPGGTPPSKAQHLLQQVLDRFYPRHYRLGAPPEQL------------
-----------------------RHLANMLAMRWASLQGRSLAEYTRTYLTVARKWPLFG
AKLFAAQPAPSSSKE-NTLVWIAINEDGVSILDRHTMQVRVTYPYSSVTTFGGYRDDFM-
-LVIRSVPDQSSGKGHIDKLIFRMAAPKIAEATFIMASYMNHCSPTARRSPA--------
--KLPAARRPRELDGQC--ASVSCATKRPALL

------------------------------------------------------------
----------------------------------MAELKVDARASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEFFLFFFNLKNVDSGG
SLHQKFFFFFFSIKGKDELISQLEALSFLQKQMSFFYFFFVQEKAAKIKEWVTLFFLFFF
WKLILHLKSHNQHLVEQVFFLFFSLE----------------------------------
--------------------------------------------------------G---
-------------------------------RQARLLVPSHGAADFFSFFLEPGIQPTGQ
N----------SGSQA---------------EG-LKAAVLA--PSPGALQ-SKDFFFVFF
CPLEDS------SSSTVHSGDFFYFFFLQPHLGREGP---------------PHQPFF-L
FFFFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRT
PGTPRDSIQLTKRHHSQPQVGHGHFDRVVSIEIFFFFFFHPSGLPELE-SR--ARYFFYF
FLMEMEEPPPAGKNEEFFF---------FFFLGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARVEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPGK--FSEPRGCWSA-----VLTAV-----
------PSQS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSMVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQAMKELHPGKSE
GGTRIVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCAPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSEE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NLPGACQLWELDGQQFFSSVSCATKGPTLL

-------------------------------------------------------ATLGQ
WRTHGXX--XXXXXXXXXXXXXXA-PW----DSIMGEPKVETQTSMDWQKRCLALETQLF
RFREQASKIRELLADK---MQELEQRLLEAEQRAENAETQMGVMEEKAKLSNLKNVDSAG
SLHRKYQDLLKALQGKDELIRQLQAQLEKQKLIRAEEAKVIQEKAAKIKEWVTLKLSELE
-TENQHLKNCNQQLEEQVGALQVALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKWLVKPQGPPKQHAALSVPVPPAMGQ
D----------NGPQG---------------QVTLEMAAVA--PSPGALQ-NKDSEPKAE
NSLQAP------RFNVAHQGEPPKAQTLPPRLRREGS---------------PGQPCM-T
PCTPRHGLASWGAG-------------LVAPH-GQPFPGTKTSAGEGGPGSSVTLPKART
PASPRDSLPLARRHHSQPQAYPGYFSHVVSREIGALSALHPPGLPEVG-AP--AEAREEP
ERMEMEEQPPAGRKSPV------------KAPHADLEEVDLGNKPPTPPLHRFPSWES-R
IYAVATSGLQLSDVSSRSNVT--------CCASRPPALASP-GPS-GLXXXXXXXXXXXX
XXXKATQISSVPLVDESSGSDDDCSSQASFRISVPCPETRKTGGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYST---EG--LGLSGXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXNDVIR

PF00169 // ENSGT00920000149052_1_Domain_0 (931, 1019)

KPQGQVELNSRCQ-----------------
------------------IVRGEDAQTFQLISEKKTYYLTADSPSLLEEWIRILQNLL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

KV
QAVGPPGPLQGATK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PTVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGRLPIRD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAA

ENSGT00920000149052_1_Linker_1_3 (1144, 1227)

GGS--CAKVGTTYEQLIGKLMDVE--DPDSPLWRHPMLCYSKDGLLAPLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLAHPELQSEIYCQLMKQASC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVRQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSRSGFALFMDDPSGRDVEHCLQGTVKICDAISKWEQALKELHSGKSE
GGTRTVKLMYKNRLYFRSQVKGETERERLLLASQTSGEIVSGRFPVNKELALEMAALMA-
-VEYGDLERSTLLGPGCTPPAKVQHHLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADLLSTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPALLSSKE-KTLVWIAANEDGVSILDHNTMQVHVTYPYSSVMTFGGCRDDFM-
-LVIRSTPDQNSGKSHIEKLIFRMAAPKIAEATFILASYMNHCSVAG-SPPT--------
--NPPTGRPPRELDGRQFFASVPCVAKGPALL

-----------------------------MKPK-L------------------LVESDKY
LKQ---------VFQGFLEHLRRHPKWMI--NFTMAELTVENGSCMDWQKRCLVLESQLF
KFRLQASKIRELLAE---KMQELEQRVIEAEQRAEDAEKQVRVMEEKIKLANVKTGESDS
TLHRKYQELMCTVQGKEDLINKLETQLAKQKQLRTEEAKIVQEKAAKIKEWVTFKLRELE
-LENFHLKNCNQRLMEQIEALQDTLQDMTSIPP---------------------------
------------------------------------------------------------
----FESLWSCD-------------S----LKPRASQASFAEKIDQKSVLLAPGFR----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------EES-R
IYAVAKSGMRLSEVAMVNETTSCF--------SNF-SCSTS-GPFTYLIYRNVTVPVYST
LKGKATQISNVPFLDESSGSDDDCGSHASFRTSTAGLENRKASMPGSPRAVKR-GVS-VS
SLSSESDYAIPPDAYSLDGDYSEPEHKLQRTSSYSTD------GGICTEPM

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSQVKTWKRRWFVLRNRQIMYYKSPSDVIRKPQGQLELNSSCQIVRGEGSQTFQVGVAFF
ILHITKPQGQLELNSSCQIVRGEGSQTFQLVTEKRTYFLTADSTSILEEWIHVLQSILRV
QVSGPVGVPHSDAKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRNHEDKCPLGHLPLRE
SKVEEVDRSCDSDEDYETTGG--GLLSSHCTLVIHPQDQSPTYLLIRTKQEKNTWLYHLT
VAAGSS--NATVGTSYEQLIGKLLDAE-GDPNSPLWKHPMLCYSKDGLHTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEASSIDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLTHTELQNEIYCQLVKQTSC
RQ--PQNHSVI-QCWQLLALCAPLFLPQHHFLWYIKQHLQRHADSR--SEIGKYAIYCQR
SVERTVQAGEREAKPSRMEIVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1465)

ILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEF
IQRLNQETGMRKPSHMGFSLFTDDPSGRNLEHCLPGNMKICDVISKWEQALKELHPGKYE
GGTRIVKLTYKNRLYFRSQAKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

DRERLLLAFQVSNEIANGRFPVNKELALEMVALMA-
QVEYGDLDRPGSSSPGGASQLRMQHLLHQVLDKFYPKHYKQNITPEQL------------
-----------------------RQLTDRLATKWMVLQGCSPAECIRIYLTVARKWPLFG
TKIFAAKPVLPSSLE-DCPVWIAVNEDGISILDYNTMHLKVSYSYSSVLTFGGCRDDFM-
-IVVSQMKERSSGKNSTEKLLFTMAIPKIVEATLLIASYINYRSNPSLLSSTQPSR----
--SKTPARKPWETENCCFLPSMPRSTKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVEV-AGVDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSSLKNVDSTG
SLHRKYQELLKAMQSKDELISQLEAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-TENEHLKACNQQLVEQVEALQDALE----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEKLLVVPEGTPEGNPVPSGPKTQAVEQ
D----------SNPHT---------------QI-LKMAVPV--PSLGTLQ-NKDSMSEAR
SLEDLSS-------SVVYPGEIAEAKTLRSHPQREGS---------------PTQLLE-K
PGSPKHVSASYRDN-------------LLTAP-GGTYPGTKISVREGGPGSSLTLPKVRA
PSNPRDSFQLAKRHHSQPHVGPGHFDHVVSIKIGTLPALPSSGFSKSE-SR--AKAREEA
EKMEMEELPPTGKREERES---------LKLPRAAPEGVELEKKPPTPPLHRFPSWES-R
IYAMATSGMQLS-DVSSQSDAACC-------ASGPPALAFP-GAFSGLVYKNVTVPVYTA
LKGKATQISNVPFVDESSGSDDDCSSQASFRMSVPCSEYRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISENKTYYLTAESPSLLEEWIRVLQSLLKV
QVIGPPALHQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SARVGTVYEQLIGKLMDGE-GDPDSPLWRHPMLCYSREGLCNSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSHVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAFQTSGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPILPGPGGTPPAKAQHLLQQVLDRFYPRRYRNGAPPEQL------------
-----------------------RHLADMMATKWAALQGCSPSECIRIYLTVARKWPLFG
AKLFAAQPAQL-SSKENTLVWIAVNEDGVSILDHHTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDHNSGKTHIDKLIFRMPAPKITETTFMMASYMNHCSATV-NPST--------
--KLPAARQPRDLDGQ-FFSSASCTKGSALL-

------------------------------------------------------------
----------------------------------MAELKVDARASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSGG
SLHQKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPSHGAAEQDSVPSEPGIQPTGQ
N----------SGSQA---------------EG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSTVHSGEMVEAKPLQPHLGREGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGIKTSAREGGPGSSLTLPKVRT
PGTPRDSIQLTKRHHSQPQVGHGHFDRVVSIEIGAFSALHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNEERES---------PKALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVQD
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRLPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NLPGACQLWELDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVEV-ASIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSNLKNGDSTG
SLHQKYQELLKAMQSKDELISQLEAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-TENEHLKAYNQQLVEQVEALRDTLA----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEKLLVVPEGTPEGNPVPSGPRTQPVEQ
D----------SNTHT---------------QI-LKVAVPA--PSLGTLQ-NKDSMSEAR
SLEDLSS-------SMVYSGEIAEAKTLKSHPQREGS---------------PSQLLE-K
PGSRKHVSASYRAN-------------LLTAP-GGTFPGTKISSREGGPGSSLTLPKVRA
PSNPRDSFQLAKRHHSQPQVGPGHFDHVVNIKIGALPALPLSGFSKSE-SR--AKAREEA
EKMEMEEPLPTGKQEERES---------LKPPRAALEEVELEKKPPTPPLHRFPSWES-R
IYAMATSGMQLS-DVSSQSDAAWC-------ASGPPALAFP-GAFSGLVYKNVTVPVYTA
LKGKATQISNVPFVDESSGSDDDCSSQASFRMSVPCSEYRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISENKTYYLTAESPSLLEEWIRVLQSLLKV
QVIGPPALHQGGAKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTVYEQLIGKLMDGE-GDPDSPLWRHPMLCYSRDGLCNSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAFQTSGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPVLPGPGGTPPAKAQHLLQQILDRFYPKRYRNGAHPEQL------------
-----------------------RHLADTMATKWAALQGCSPSECIRIYLTVARKWPLFG
AKLFAAQPAQL-SSKENTLVWIAVNEDGVSILDHHTMQVHITYPYSSVTTFGGCKDDFM-
-LVIRSIPDQSSGKTHIDKLIFKMPAPKITETTFMMASYMNHCSATV-NLSS--------
--KLPAARQPRDLDGQ-FFASASCTKGPALL-

------------------------------------------------------------
----------------------------------MAELKVETRANVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEQKVKLSHLKNVDSAG
SLHRKYQELMKVTQGKDELISQLEAQLEKQKQMRAEEAKIVQEKAAKIKEWVTLKLAELE
-MENQHLQSCNQRLVEQVGALQDALE----------------------------------
--------------------------------------------------------AVRM
------------------------------APSGKLLVAPQETPEQMLSLQGPGKP-ADG
D----------SGPQT---------------EG-FMKVGKGLYFFPGALQ-NKR-SLEAG
SPLDDS------HSSLVHSGERAEAKTPQGHLGREGS---------------PGQLRV-K
PRIPRCGSTSWGEG-------------LVSVQ-GGMLPGTKISIREGGPGSSLTLPKTRT
PSTPQDSIHLAKRHHSQPQVGSGHFDHVVSIEIGALPALCPSSLLEVK-TG--AELREEP
EKMEMEEPPPAGKKEEQES---------LKIPGADLGEAELGNKPPTPPLHRFPSWES-R
IYAVAISGMQLSDAAPRSNTASCA--------SSPPALVFP-GPFSGLVYKNVTVPVFTA
LKGRATKISSIPFVDESSGSDDDCSSQASFRTSVTCSEPRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLSL

PF00169 // ENSGT00920000149052_1_Domain_0 (887, 1019)

GG----KSGYLLKM
GSRVKTWKRRWFVLRQRQIMYYKSPNDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

KV
QAVGPPALPHSGTK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGHLPMRD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIRPAEHSPTYLLIGTKHEKDTWLYHLT
VAA

ENSGT00920000149052_1_Linker_1_3 (1144, 1227)

GGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPVLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLVHPELQSEIYCQLMKQSNC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYIKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFSLFTDDPSGRDLEHCLQGSVKICDVISKWEQALKELHPGKSE
GGTRIVKLMYKNRLYFRSQVKGETERERLLLASQTNGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPTLPGPGGTPPAKAQHLLQQVLDRFYPRRYRHGPPAEQL------------
-----------------------RHLADTLTTKWLALQGCSSPECIRIYLTVARKWPFFG
AKLFTAQVMELSSKE-NTLVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIQDQNSGKGHIEKLIFRMAAPKIAEATLIMASYMNHCSATV-SPPT--------
--NPPASRQPWELDGRQFFASIPRATKRPTLL

------------------------------------------------------------
----------------------------------MAELKVDARASVDWQKRCLTLETQLF
RFRLQASKIRELLADK------------------------VGVMEEKVKLSNLKNVDSAG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTIQEKATKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSWKLLVPPHGAAEQDSVPSEPGIQPMGQ
N----------SGSQA---------------QG-LKAAVLA--PSPDALQ-SKDSVSEAA
SPLEDS------SSSTVHSGEMVEAKPLQPHLGREGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLAKRHHSQPQVGRGHFDRVVSIEIGAFSALHPSGLLELE-SR--ARYLEEP
EKMEMEEPPPAGKNEKRES---------PKAL-AELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPLGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALLA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NPPGACQLWEMDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELKVEKRASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSSLNNVDSAG
SLHRKYQELLKAIQGKDDLIGQLEAQLEKQKQMRAEEAKIVQEKAAKIKEWVTLKLAEVS
QN-----SFCSARV-------FAPPA----------------------------------
--------------------------------------------------------TLQM
------------------------------APSGRPRAASREAPGQDSVPPGPGSQPVGQ
V----------CGPQA---------------QR-LKAAAPG-----------QESVPEAG
GPAEAA------ASSVARSGGAAEAKAPLRHPGRAGS---------------PCRLCL-N
PPAPGRGSASWDEG-------------LAPAR-GGRLPWTKTSIQEGGPGGSLTLPKVRA
PGSPQDSVQVARRHHSQPQGCSGPLGPVVSIEIGAFSALPRSRLPEPQ-HR--VGLREEL
ERMEMD---------ERDG---------PKAPGAELEEAELGSKPPTPPLHRFPSWER-R
IYALASSGMQLSDVSPRSNATCCP--------SSLSALASP-GPFSDLVYKNITVPVYTA
LKGRATQISTVPFVDESSGSDDDGCSQASFRTSIPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLLRDSSLLFCLSPPPHPFTPQELL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPALLEEWIRVLQSLLRV
QATGPPTLPRGGTKPTVKGWLTKVKHGHSKLVWCALVDKTFYYYRSHEDKRPLGHLPVRD
ACIEEVDRSCDSDEDYEA-SGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMAGK-GDPDSPLWRHPMLCYSKDGLFTPLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKHSLM-QCWQLLALCAPLFLPQHPFLWYVRQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1467)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEL
VQRLNQDTGMRRPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRVVKLMYKNRLYFRCQVKGETDR

PF00373 // ENSGT00920000149052_1_Domain_4 (1467, 1624)

ERLLLTSQINGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPILSGPGGTPPAKAQHLLQQVLERFYPQRYRHGVPHEQL------------
-----------------------RHLADTLTTKWAALQGCSTPECIRIYLTVARKWPFFG
AKLFAAQPAQLSPKE-NTLVWIAVNEDGVSILDHNTMQVHVTYPYSSVMTFGGCRDDFM-
-LVIRSIPDQSSRKDRVEKLVFRMAASKIAEATLILASYMNHCSATV-TPPI--------
--SPPAPHQPWELHGRQFFASVRCASKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVEV-VGIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSNLKSVDSTG
SLHQKYQELLKAMQGKDELIGQLQAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-MENQHLKTCNQQLVEQVAALQDALE----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEELLGVPEGTPEGDPVPSGPSAQPVEQ
D----------SNPNT---------------QI-SKVAVPT--P-LGTLQ-SKDFLSEAR
SPEDLSF-------SMAHPGDIAEAKTLQSHLQREGS---------------PSQPFM-K
PGSPRCGSASYREG-------------LITAQ-GGTFPGTKISAREGGPGSSLTLPKVRA
PSIPRDSFQVAKRHHSQPQVGPGHVDHVVSIEIGALSALHSSGLPKSE-AR--AKVREEA
EKMEMEELPPMGKKGERES---------LKPRRGELEGVEPENKPPTPPLHRFPSWER-R
IYAMATSGMQLSDVSSR-NTASCF-------ASGPPALAFP-GAFSGLIYKNVTVPVYTA
LKGKATQISNVPFVDESSGSDDDCGSQASFRMSVPCSEYRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSAYSTD-----G-----ETL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPNDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEEAQTFQLISGNKIYYLTAESPSLLEEWIRVLQSLLKV
QVTGPPALHQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTVYEQLIGKLMDGE-GNPDSPLWRHPMLCYSQEGLCASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQISR
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYAIYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1464)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPS------FTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGE

PF00373 // ENSGT00920000149052_1_Domain_4 (1464, 1624)

TERERLLLAFQTSGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPTLPGPGGTPPAKAQHLLQQVLDRFYPRHYRNGAPPEQL------------
-----------------------RHLADMMATKWAALQGCSPPECIRIYLTVARKWPLFG
AKLFAAQPAQPLSSKENTPVWIAVNEDGVSILDQRTMQVNITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQNSGKTRIDKLTFRMPAPKITDTTLVMASYMNHCSATV-NLSA--------
--KLPAARQPRDLDGQ-FFASVSCTKGSALL-

------------------------------------------------------------
----------------------------------MAELKVDARASVDWQKRCLTLETQLF
RFRLQASRIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSGG
SLHQKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPSHGAAEQDSVPSEPGIQPTGQ
N----------SGSQA---------------EG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSMVHSGEMVEAKPLQPHLGRAGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRT
PGTPRDSIQLTKRHHSQPQVGHGHFDRVVSIEIGAFSALHPSGLPELE-FR--ARYWEEP
EKMEMEEPPPAGKNEERES---------PKALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVQD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPRKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGATSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NLPGACQLWELDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVESRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKLKLCSLKNVDGTG
SLPCRYQELLKAVQCKDELIRQLQGQLEAQKRMRAEEAKIVQEKAAKIKEWVTLKLAELE
-TENQHLKSCNRHLVEQVGALQDALD----------------------------------
--------------------------------------------------------ALRM
------------------------------VPSGKLMS-SQESPEQDFVPSEPGPQPVGQ
D----------PGPQA---------------QG-FKVSVPE--DSPGSLQ-SRDLVCEAR
SSLDDS------SPSVIQSGKTAEAQTLQPHLGREGS---------------PSRLCV-K
ARAPRRGSASWGEG-------------LLTAR-GGLLPGTKTSVREGGPGSSLTLPKARA
PGTPRDSIQLAKRHHSQPQVGPGHLDHTVRIEIGVLPVLHPSGLPKLK-TP--AQIWEEP
EKMEMEEPLPAGKKDVRAS---------LKAPGSELEEVELGSTPPTPPLHRFPSWES-R
IYAVATSGMQLSDVSPRSNAACCA--------SSPPALTSP-GPFCGLVYKNVTVPVYTA
LKGRAMQISSVPFMDESSGSDDDCSSQASFRMSVPCSESRKTSGLGSPRAIKRG-VS-VS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSPD-----RLGPGTESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCR-----------------
------------------IVRGEGAQTFQLVCEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALPQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGRLPVRD
ARIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPTLCYTRQGLAASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSRM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1463)

ILLRNPFHHSLPFSIPVHLANGTYQVVGFDGSSTVDEF
LQRLNQEMGMRRPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKTE
GGTRVVKLMYKNRLYFRSQVKG

PF00373 // ENSGT00920000149052_1_Domain_4 (1463, 1624)

ETERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPVLLGPGGTPPGKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADTLTTKWAALQGCSAPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKEESPLVWIAVNEDGVSILDHSTMQVHVTYPYTAVTTFGGCKDDFM-
-LVIRSIPDQSSGKGHIEKLTFRMAAPKIAEATFIMASYMNHHSTTV-CPPT--------
--DPPAVHQPWDLDGRQLFASVPCATKGPTLL

------------------------------------------------------------
------------------------APWNPEVDSIMAELKVETRASVDWQKRCLALETQLF
RFRLQASKIRELLADKXXXXX---XXXXXXXXXXXXXXXXVGVMEEKVKLSNLRHVDSAG
SLHQKYQELLKAMQGKDELIGRLEAQLEKQKQMRAEEAKVVQEKAAKIKEWVTVKLAELE
-MENQHLKSCNQHLVEQVGALQDALQ----------------------------------
--------------------------------------------------------ALQM
------------------------------APAGKLLVAPQGPAEQASVPSGLGAQPVGQ
D----------SDLQA---------------QGALKAXXXXXXXXXXXXX----------
-------------------------------------------------------XXX--
--------XX-----------------XXXXX----------------------------
--------------X------XXXX----------------------X-XX---------
---------------XX-X-----------XX----------------------------
------------------------------------------XXXXXXXXXXXXXXXXXX
XXXRATQISAVPFVDESSGSDDDCCSQASFRTSVTCSESRKTSGMGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYCGIXXXXXXXXXXXX--XXXXXXXXXXES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKIWKRRWFVLRQGQIMYYKSPSDVIRKLQGQVELNSRCQ-----------------
------------------IVRGEGAQTLQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QAIGPPALPQVGTKPTVKGWLT--------------------------------------
---------------------------------------------------KDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXX
XX--XXXXXXXXXXXXXXXXCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFANGTYQXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXX-XX-X
XXXXXXXXXXXXXXXXXXXXXXXX---XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX-
XXXXXXXXXXXXXX-XXX---XXXXXXXXXXXXXXX--------------------XXXX
XXXXXXXXXXXXXXXXXXXXEQLRHLADQLTTKWAALQGCSSPECVRIYLTVARKWPFFG
AKLFAAQ-----------------------------------------------------
------------------------------------------------------------
--------------------------------

----------------------------------------------------AAQGQRRR
LRWRARGAREPCARRG-PRARGRP-PRNLEVVSIMAELKVETRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---XXXXXXXXXXXXXXXXXXXXXMGVMEEKVKLSNMKNLEATG
SLPRKYQELLQVLQCKDELIRRLEAQLEAQKQMRAEEAKTVQE-AAKIKEWVTLKLAELE
-MENQQLKSCNQPLAEQVGALQDALA----------------------------------
--------------------------------------------------------ALRM
------------------------------TPSGKLLVSSQETPEKECAPSGPGAQPVPQ
D----------SGSQA---------------QG-FKASVPA--ASPGAVQ-SKDLVCEAQ
SPLEDS------SSSVTPCGKTAEAQLLQPHLGREGS---------------PSRLGV-K
PHAPRYGSAPWGEG-------------LVPAQ-GGMLSVTKTYVKAGGPGSSLTLPKARA
PSTPRDSIQLAKH-HSQPQV-PGHLDQVVSNEIGTLSVLYPAGLPKLK-AA--AQILEEP
EKMEMEEPPAARKKEDRES---------PKASGAGQEEAELWCKPPTPPLHRFPSWES-R
IYAVATSGMRLSDASSRSSAACCA--------SSPPALASP-GPFSGLVYKNVTVPVYTA
LKGRATQISNVPFVDESSGSDDDCSSQASFRTSVPCSESRKASGLGSPRAIKRG-VS-VS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSPD-----GLGPGAES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IIRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPAMPQGGTKPTVKGWLTKVKNGNSKLVWLALGGKTFQEYSTHKNKRPLGRLPVRD
ARIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWKHPTLCYTRHGLAASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLV-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQAGEREARPSRMEVVSILLRNPFHHSLPFSIPVHLANGTYQVVGFDGSSTVDEI
LQRLNQETGMRRSSHSGFALFTDDPSGRDLEHCLQGSIKICDAISKWEQALKELHPVKTE
GGTRVVKLMYKNRLYFRSQVKGETERERLLLACQASGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPVLPGPGGTPPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADTLSTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-SPFVWLAVNEDGVSILDHNTMQVHTTYPYATVTTFGGCKDDFM-
-LVIRPIPDQSSGKGHVEKLIFRMAAPKIAEATLIMASYMNHHATTV-TPPT--------
--QLPVDPQPWELDGRQLFASVPGATKGPTLL

------------------------------------------------------------
----------------------------------MAEFKVDTQASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEERAEKAETQVGVMEEKVKLSNLRNVDSTG
SLHRKYQELLKAMQSQVELISQLEAQLEKQKQMRAEEAKIVQKKAAKIKEWVALKLTELE
-MENQHLKSCNQHLVEQVGALQTALEGRLPAWAGCVCDVCV----GCVHECVCVGGGMYM
RGVWRVWGTVERALTGLV---------SVA------------------------TTALQM
------------------------------APSGKLLVIPKGTPELESVPAESGAQPVGQ
D----------SGSQA---------------LD-LKVAIPA--PSLDAPKSSKGFLSQAR
NSTEDS------CSSTFHPEEVAETTVLQPHLESEHF---------------PSQLCV-K
PGASGCGSASCGEG-------------VVTAQ-ERVLPGIKTSAREGGPGSSLTLPKVRA
PSTPQDSIQVTKRHHSQPHVGPRRFEHVMNAESGALSALHPFGLSKLE-TY--ADFWEEP
EKMEMGELPPAGKEEERKS---------LKAPTTELEEVKLGNKPPTPPLHRFPSWES-R
IYAVATSGMQVSDVSPQSNAAGCA--------SSPPALVCP-GPFSGLTYKNVPVPVYTA
LKGKATQISSVPFLDESSGSDDDCSSQASFRMSVPCSECRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKMQRTSCYSTE---GQGLGTGTESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSSYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPNDVILKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLMADSPSLLEEWIRALQSLLKV
QATGPPALSQGGTKPAVKGWLTKVKHGHSKLVWCALIGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-AGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VVAGGS--SGKVGTAYEQLIGKLMDGE-GDPDSPLWRHPTLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTVLQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSHMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSQSGFALLTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRIVKLMYKNRLHFRSHVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAYQTNGEIVAGRFPVSKELALEMASLMA-
QIEYGHMEKPILPGPGGTPPAKAQHLLQQVLDRFYPRHYRHGAPPEQL------------
-----------------------RHLANMLATKWTSLQGCSLAEYTRTYLTVARKWPLFG
AKLFAAQPAQLSSKE-NTLVWIAVNEDGVSILDHHTMQVHVTYPYSSLTTFGGCRDDFM-
-LVIRSTPDQSSGKGHIDKLIFRMAAPKIAEATFIMASYMNHCSATV-NSPT--------
--YLPAAHLPRELDGQQFFASVSCATKGPILL

------------------------------------------------------------
----------------------------------MAELTAENGSCTDWQKRCFMLETQLF
KFRLQASKIRELLAE---KMQELEQRVAEAEDRAQSAEKQVEIMEEKLKLANMKTNES--
NEYKKYQQMMSRVQEKDELIEKLEVQLEKQKLLREEEAKTVQEKAAKIKDWVTAKLRELE
-VENHYLKDCNTRLTDQIKALQAALQENILSKKELSIRSVCCFHGILFSNYPSHPAKVS-
-------------------QRMNCS----------------------------RSSYLVT
VPS-EESVSSCN-----------------IKLLRDPLSCLLENSNQDPRLLAVDIKQTCQ
DVSTQGIPYIASVVFMDESSVADAVDKSMLSQSSLRLISD---SSNNNNASVNDLISMAE
SP---F--CTTSLKHKVEAVKIRGALTFPSPLEECNNLTSASDKAVHNLYKTSDEMNS-E
INTSRWTSSCSGEMRNICRSSVSASTPALKLQKSIMSIPSHFPGKEGGLGSSMTLPKVRT
PSNPRDSILLAKRHYSQPQSGSDCLHHVVNIEISTFHPKRATAHCQGKVEETDIDEE-VA
EKMETDDRVVEMHPLSCPRSET--------NTPETTIVLDPGGKPPTPPLHRFPSWES-R
IYAVAKSGMRLSEVALASDSSGHA--------SDFPTYSSP-GPYTCHIYKNVTVPVYTM
LKGKATQISNIPFVDESSGSDDDCSSHVSISTSNAGCELRRTSMPGSPRAVKRAGVS-MS
SISSESDYAIPPDAYSLEEDYSEPEHKLQRTSSYSTD------GGVGNELL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GDQVKAWKRRWFVLRNGQIMYYKSPSDVICKPQGRIELNPSCQ-----------------
------------------IVRCEGSHIFQLITEKRTYFLTADSPNILEEWIRVLQNILKV
QVTSPSQVSLRDAKPSVKGWLTKVKHGRSKLVWCVLIGKIFYYYRNQEDKCPLGHLHLHE
SKVEEVDRSCDSDEDYETHGG--NLLSSHCTLVIHPPDQSPTYLLIGTKQEKDTWLYHLT
VAAGSSKSSAKVGTAYEQLIGKLLDAE-GDPNSPLWKNPVLCYSKDGLQMPLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAPSIDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VTLAQTALQVCLTHSELQNEIYCQLMKQTSR
EAQKAEEPAPL-QCWQLLALCSPLFLPQHHFLWNLKHHLQHHADPK--SEIGKYAIYCQR
SMEHTLKAGEREARPSRMEIVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1464)

ILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEF
LQRLNQETGMRRSALSGFYLFTDDPSGRDLEHCLQSPVKICDIISKWEQALKELNPGKYD
GGTRIVKLTYKNRLYFRSQAKAE

PF00373 // ENSGT00920000149052_1_Domain_4 (1464, 1624)

TDRERLLLAFQINGEIVNGRFPVNKELALEMAALMA-
QVEYGDLDRPIPSNPGGSPHSKMQHFLQQVLDKFYPKRYRHSTSSEQL------------
-----------------------RRLADRLATKWMVLQGCSMQECVRIYLTVARKWPLFG
AKLFTAKPVLPSSLE-DAPLWIAVNEDGISILDYNTLHLKLAYSYSSVLTFGGYHDDFM-
-IVVSQVKDRCSGKANPEKLLFTMASVKIVEVTLLIASYINCCSSTPHLSPGPPAQIISP
PWSTSSAKKLMGHESRSFFPSLPRTTKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVEV-ASIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSNLKSVDSTG
SLHQKYQELLKAVQGKDELISQLQAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-MENQQLKTCNQQLVEQVAALQDALE----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEELLVVPEGTPERDPVPSGPSDQPVEH
D----------NNPHA---------------HI-LKVAVPT--PSLGNLQ-STDSLSEAR
SLEDLRF-------NMVHPGETAEAKTRQSHLQKEGS---------------PSQLCM-K
PGSPKHGSASYRES-------------LVTAQ-GGTFPGTKISAREGGPGSSLTLPKVRA
PSIPRDSFQVAKRHHSQPQVGPGHCDHVVSIEIGALSALHSSGSSKSE-AR--AKIREEA
EKMEMEALPPSGKQEERES---------LKPRRGELEDVELENKPPTPPLHRFPSWES-R
IYAMATSGMQLSDVSSRRSNAACY-------ASGPPALAFP-GAFSGLVYKNVTVPVYTA
LKGKATQISNVPFVDESSGSDDDCGSQASFRMSVPCSEYRKTGGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEEAQTFQLISGNKTYYLTAESPSLLEEWIRVLQSLLKV
QVTGPPALHQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVQD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTVYEQLIGKLMDGE-GNPDSPLWRHPMLCYSQEGLCASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQISC
RP--PQKYSLM-QCWQLLALCAPLFLPQQHFLWYVKQQLQRHADPR--SETGQYAIYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAFQASGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPMLPGPGGTPPAKAQHLLQQVLDRFYPRRYRNGAPPEQL------------
-----------------------RHLADMMATKWAALQGCSPPECIRIYLTVARKWPLFG
AKLFAAQPAQ-LSSKENTVVWIAVNEDGVSILDYRTMQVNITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKTHIDKLTFRMPAPKITETTLMMASYMNHCSATV-NLSA--------
--KLPAARQPRDLDGQ-FFASVSCTKGSTLL-

------------------------------------------------------------
----------------------------------MAEVKVEV-ASIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSNLKNGDSTG
SLHQKYQELLKAMQSKDELISQLEAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-TENEHLKAYNQQLVEQVEALRDTLA----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEKLLVVPEGTPEGNPVPSGPRTQPVEQ
D----------SNTHT---------------QI-LKVAVPA--PSLGTLQ-NKDSMSEAR
SLEDLSS-------SMVYSGEIAEAKTLKSHPQREGS---------------PSQLLE-K
PGSRKHVSASYRAN-------------LLTAP-GGTFPGTKISSREGGPGSSLTLPKVRA
PSNPRDSFQLAKRHHSQPQVGPGHFDHVVNIKIGALPALPLSGFSKSE-SR--AKAREEA
EKMEMEEPLPTGKQEERES---------LKPPRAALEEVELEKKPPTPPLHRFPSWES-R
IYAMATSGMQLS-DVSSQSDAAWC-------ASGPPALAFP-GAFSGLVYKNVTVPVYTA
LKGKATQISNVPFVDESSGSDDDCSSQASFRMSVPCSEYRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISENKTYYLTAESPSLLEEWIRVLQSLLKV
QVIGPPALHQGGAKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTVYEQLIGKLMDGE-GDPDSPLWRHPMLCYSRDGLCNSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAFQTSGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPVLPGPGGTPPAKAQHLLQQILDRFYPKRYRNGAHPEQL------------
-----------------------RHLADTMATKWAALQGCSPSECIRIYLTVARKWPLFG
AKLFAAQPAQL-SSKENTLVWIAVNEDGVSILDHHTMQVHITYPYSSVTTFGGCKDDFM-
-LVIRSIPDQSSGKTHIDKLIFKMPAPKITETTFMMASYMNHCSATV-NLSS--------
--KLPAARQPRDLDGQ-FFASASCTKGPALL-

------------------------------------------------------------
----------------------------------MAELQVGTQASVDWQKRCLTLETQLV
RFRLQASKIRELLADK---MQELEQRLLEAEERAEKAETQVGVMEEKVKLSNLRNVDSAG
SLHRKYQELLKAMQGKVELISQLEAQLEKQKQMRAEEAKVVQKKAAKIKEWVALKLTELE
-MENQHLKSCNQHLMEQVGTLQAALE----------------------------------
--------------------------------------------------------ALQM
------------------------------GPPGKLPVIPKGAQEQESVPAEVGAQPVGQ
D----------GGSQA---------------PD-FKAAVPI--PSLDASE-SKGFLSEAR
SPVEDT------SSSALHPGEVAKAKVLQPHLESEHF---------------PSQLCM-K
PGAPRRGSASCGDS-------------LVPAQ-ERVLLGIKTSAREGGPGSSLTLPKVRV
PSSPQDSIQMTKRHHSQPSVGPRHSEHVVNVEVGALSTVHTSGLSKLE-TC--ADFREEP
EKMETGELPPAGKEEERGS---------LKAASTKLEDVRLGSKPPTPPLHRFPSWES-R
IYAVATSGMQVSDVSPRSSAACCA--------SSPPALVCS-GPFCGFVYKNVTVPVYTA
LKGKATQISSVPFMDESSGSDDDCSSQASFRMSVPCSECRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKMQRTSCYSAE---W--LGLGMESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPNDVILKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLMADSPSVLEEWIRALQSLLKV
QATGPPALLQGGTKPAVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVGD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAQVGTAYEQLIGKLMDGEGGDPDSPLWKHPILCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTVLQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVRQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSHMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPCGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRIVKLMYKNRLHFRSQIKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLTYQTNGEIVAGRFPVSKELALEMAGLMA-
QIEYGDMEKPILPGPGGTHPAKAQHLLQQVLDRFYPRHYRLGAPPEQL------------
-----------------------RHLTSMLATRWASLQGRSLAEYTRTYLTVARKWPLFG
AKLFAAQPAKLLPKE-NTLVWIAVNEDGVSILDHHTMQVQVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKGHIDKLIFRMAAPKIAEATFIMASYMNHCSVPA-SSPT--------
--SLPAARPLRELDGRQFLAPVSCAAKGPTLL

------------------------------------------------------------
----------------------------------MAELKVDARASIDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSGG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPNGAAEQDSVPSEPGIQPMGQ
N----------SGSQA---------------QG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSTVYSGEMVEAKPLQPHLGREGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLTKRHHSQPQVGCGHFDRVVSIEIGTFSALHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNEERES---------PKALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRQLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1464)

ILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSVVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRNQVKGE

PF00373 // ENSGT00920000149052_1_Domain_4 (1464, 1624)

TDRERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWLAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NLPGACQLWELDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------PQVAPIMAELTVETRTSVDWQKRCLALETQLF
RFRLQASKIRELLADKAEQMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLMNVDSAG
SLHRKYQELLKAMQGKDELISELEAQLEKQKQMRAEEAKVVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQHLVEQVGALQCALE----------------------------------
--------------------------------------------------------ALQM
------------------------------SPSGKLLVAPQGTTERESVPSGPGAQPVGQ
D----------SGPPA---------------QGALKAAIPA--PFPGALQ-SKDSVPKAG
SPVEDS------SSRTVHPGATSEAKTLPLHPGRQGS---------------PGQLCL-R
PRTPRHGLASWGER-------------LVTAQ-GGTLPRTKTSAKEGGPGCSLTLPKARA
PSTLRDSIQLAKRHHSQPQAGPGHFSHVVRIEVGTLSAFHPSSLPKGV-VR--AEPREEP
EKMEMEEQPPMGKKE---------------AQGTELEEVDLENKPPTPPLHRFPSWES-R
IYAVATSGMRLSEPIPSHNRE--------CCPSSPPALASP-GPFSGLVYKNVTVPVYTA
LKGKATQISTVPFVDESSGSDDDCSSQASFRTSVPCSESRKTSGLGSPRAIKR-GVS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYS-T--DG--LGPGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QAIGPPALPQGGTKPTVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGRLPVRN
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHYTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLFTSLTTLPSEAL
QTEAVKLFKKNECLVYVIHRVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLAHPELQSEITCHLRNRPCC
RP--PQKYSLM-QCWQLLSLCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1463)

ILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSRSGFALFTDDPAGRDLEHCLQGSAKICDAISKWEQALKELHTGKSE
GGTRVVKLMYKNRLYFRSQVKG

PF00373 // ENSGT00920000149052_1_Domain_4 (1463, 1624)

ETERERLLLASQTNGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPILPGPGGTPSAKAQHHLQQVLDKFYPRRYRHGAPPEQL------------
-----------------------RHLADQLTTKWAALQGCSSPECIRIYLTVARKWPLFG
AKLFAAQPAQLSSKE-SALVWIAVNEDGVSILDHNTMQLHVTYPYSSVMTFGGCRDDFM-
-LVIRSLADQSSGKGHVEKLTFRMAAPKIAEVTFILASYMNHCSTAV-NPPT--------
--TPAAACQPWELDGRQFFASVPCGAKGPTLL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------QKQMRAEEAKGVQEKAAKIKEWVTLKLAELE
-MENQHLKSSNEQLVEQVGALQDALA----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLMNPQEAPEQDSAPLGSGTQPIGQ
D----------SGPHA---------------QGALKAAMPS--PSLGALQ-SKDSGPKAG
LSLEES------SSIVVHPGERVEAKTLPPPLRREGS---------------PRRPCM-K
LSIHRHGSASWGEG-------------LVTAQ-GGALPGTKNSAREGSPGCSLTLPKVRV
PSTPRDSIQLAKRHHSQPQVGPGCFNHVVSIEMGTLSALHPSSLPEAE-AR--AGPREAP
ESMEVEEPPPAGKKEERES---------PKARRAEWEEVELGSKPPTPPLHRFPSWES-R
IYAVATAGMRLSDASPRTNAA--------CCASSPPALASP-----GLVYKNVTVPVYTA
LKGRATQISTVPFVDESSGSDDDCSSQASFRTSVPCCEPRKTSGLGSPRAIKRAGVS-MS
SLSSEGDYAIPPDACSLDGDYSEPEHKLQRTSAFS-G--EG--PGLGGES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSCCQ-----------------
------------------IVQGEGAQTFQLISEKKTYYLTADSPGLLEEWVRVLQSLL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

KV
QAVGPPALPRGGTK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PAVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGHLPVRD
ARIEEVDRSCDSDEDYEA-GGSRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAA

ENSGT00920000149052_1_Linker_1_3 (1144, 1227)

GDS--SARVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEAVKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQAALQVCLAHPELQSEIYCQLMKQTSC
RP--PQKCSLV-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVSILLRNPFHHSSPFSIPVHFTNGSYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSIKICDAISKWEQALKELHSGKAE
GGTRVVKLMYKNRLYFRSQVKGETERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPSPPGPGSTTPAKVQHHLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADLLTTKWTALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQMSSKE-STLVWIAVNEDGVSILDHNTMQVHVTYPYSSVMTFGGCWDDFM-
-LVIRSIPDQSSGKGHIEKLLFRMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NPPAAHRLWELDGQKFFASVPCAARGPTLL

------------------------------------------------------------
----------------------------------MAELKVDAPASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---VSPAEQG---------AASPHVGVMEEKVKLSNLKNVDSEG
SLHQKYQELLKAIKGKDELISQLEAQLEKQKRMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSRNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSQKLLVPPHGAAEQDSVPSEPGIQPMGQ
D----------SGSQA---------------QG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSTVHSGETVEAKPLQPHLGRESP---------------PHQPCM-K
LRTFRCGSASWGES-------------LVTAE-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLAKRHHSQPQVGRGHFDRVVSIEIGAFSSLHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNEERD---------------TELEEVELGNKPPTPPLHQFSSWS--R
IYAVATSGMRLSDVSPRSNSACCV-------TSSPPALASP-GSFSGLVYKNVTVPVYTA
LKGVRNCCTNRGC-------------------------------LIRKGPWTHR-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSL

ENSGT00920000149052_1_Linker_0_1 (1018, 1038)

LKV
QATGPPALPRGGTKPTV

PF00169 // ENSGT00920000149052_1_Domain_1 (1038, 1140)

KGWLTKVKHGHSKLVWCALVGKTFYYYRNHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPTEHSPTYLLIGTKHEKDTWLYHL

ENSGT00920000149052_1_Linker_1_3 (1140, 1231)

T
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLRTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHSGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPLEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-HALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCTTTV-NPPT--------
--NPPGACQLWELDGQQFFSSVSCATKGPTLL

-------------------------------------------------------RTQGQ
RRARAKGVRVPGARRGRPRARR---ALNFDIGSIMAELKMETRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---XXXXXXXXXXXXXXXXXXXXXVGVMEEKVKQSNLKSVDSAG
SLHWKYQELLKVMQAKDKLINQLEAQLEKQEQMRAEEAKVIQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQSLVEQVGALQNALE----------------------------------
--------------------------------------------------------AIHM
------------------------------PPSGKLLVALQETPKQDAATSGSGTQPFRQ
D----------SGPQT---------------KGSMKVAMPA--PSPDAFQ-NKDSVPGAG
SPLDSS------GSSLVHCGKRAEAKSPEAHLGRECS---------------PGQLCL-K
PHTPRCS-TSWGED-------------LVRAH-GGTLSGTKISPREGGPGTSLTLPKARA
SGIPRDSIQLXXXXXXXXXXXXXXXXXXLSIGIGALSALHPSSLFKGK-TG--AELQEEL
EKMEMEEPPPVGKKEGRES---------LKIPGADLGEVELGNKPPTPPLHRFPSWES-R
IYALAISGMQLSDAAPRSNTASYA--------SSPPALASS-GPFSGLVYKNITVPVFTA
LKGRATQISSMPFVDESSGSDDDCSSQASFRTSVPCSESRKTSALGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGTES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRILQTLLKV
QATGPPALPHGGTKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRSHEDKRPLGHLPMRD
ARIEEVDRSCDSDEDYEA-GGTGRLLSSHRTLVIYPPEHSPTYLLIGTKHEKXXXXXXXX
XXXXXX--XXXXXXXXXXXXXXXXXXX-XXXXSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYIKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTIDEF
LQRLNQETAMRKSSHSGFSLFTDDPSGRDLEHCLQGSVKICDVISKWEQALKELHPGKSE
GGTRIVKLMYKNRLYFRSQVKGETERERLLLASQTSGEVVAGRFPVNKELALEMAALMA-
QVEYGDLEKPIQPGPGGTPPAKAQHLLQQVLDKFYPKRYRHGAPPEQL------------
-----------------------RHLTDMLTTKWGALQGCSPSECLRIYLTVARKWPFFG
AKLFTAQPAQLSSKE-NAVVWIAVNEDGVSILDHNTMQVHVTYXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXXXIAEATLLMASYMNHCSATG-NPPA--------
--NPPASRQPWELDGQQLFASIPHGTKEPALL

------------------------------------------------------ATQGQQ
RRRRVQGASVPGARRGRPRARRT--PWNPEADSIMAELKVETRASVDWQKRCLALETQLF
RFRLQASKIRELLADR---MQDLEQRLLEAEQRAEDAETQVGVMEEKVKLSNLKNVEPAG
SLHRKYQELLKAMQGKDELISQLEAQLEKQKQMRAEEAKIVQEKAAKIKEWVTLKLAELE
-MENQHLKSCKQRLEEQVGTLQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVAPHRVPEQDSIPSGPGAQPVGQ
G----------SGLQA---------------QD-LKVAIPA--PSLGALQ-SKDSVSEAR
SPREDF------SSSVAYSREVAETKSLQPHPRREDS---------------PSHLCVYV
PHAPRRGSASWGEG-------------LATVH-GGMLSGTKASAREGGPGSSLTLPKVRA
PGIPWNSIQGAKRHHSQPQVGPGHFDHVVSFEIGALSALHPSGLPKLR-AQ--AELPEEP
EKMEMEEPPTAGKKEERES---------LKPPGADLEELELGTKPPTPPLHRFPLWXX-X
XXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXX--XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXXXXX-XXXXXXXXX--XXXXXXXXXXXXXXXXX-XX-XX
----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRRPQGQVDLNSSCH-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

KV
QATGPSALPPGGTK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGRLPVRN
ARIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKREKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYTKDGLYSSLTTLPSEAL
QTEALKLFKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX--XXXXXXXXXXX
XX--XXXXXXX-XXXCQLAL-CPLFLPQHHF-WYVKQQLRRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVCILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
XVEYGDLEKPILPGPGSAPPAKAQHLLQQVLDKFYPRRYRHGAPPEQL------------
-----------------------KLLTDMLTTKWAALQGCSPSECIRIYLTVARKWPFFG
AKLFVAQPAQXXXXXXXXX-XXXXXXXXXXXXXXXXXQVQVTYPYSSVMTFGGCRDDFM-
-LVIRSHPDQGSGKGHIEKLIFRMAAPKIAEATFIMASYMNHCSGTV-NSST--------
--SLAAAHHPWELDGRQFFASVPCATKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVEV-ASIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSNLKSVDSTG
TLHQKYQELLKAAQGKDELISQLQAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-MENQQLKTCNQQLVEQVAALQDALE----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEELLVVPEGTPERDPVPSGPSDQPVEQ
D----------SNPHT---------------QI-LKVAVPT--PSLGTLQ-SRDSLSEAR
SLKDLRF-------SMVHPGETAEAKTLQSHLQKEGS---------------PSQLCM-K
PGNPKHGSASYRES-------------LVTAQ-GGTFPGTKTSAREGGPGSSLTLPKVRA
PSIPRDSFQVAKRHHSQPQVGPGHCDHVVSIEIGALSALHSPGSSKSE-AR--AKVREEA
EKMEMEALPPSGKQEERAS---------LKSRRGELEDVELENKPPTPPLHRFPSWES-R
IYAMATSGMQLSEVSSRRSNAACY-------ASGPPALAFP-GAFSGLVYKNVTVPVYTA
LKGKATQISNVPFVDESSGSDDDCGSQASFRMSVPCSEYRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVREEEAQTFQLISGNKTYYLTAESPSLLEEWIRVLQSLLKV
QVTGPPALHQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVQD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--NAKVGTVYEQLIGKLMDGE-GNPDSPLWRHPMLCYSQEGLCASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASIDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQISC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYAIYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1464)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGE

PF00373 // ENSGT00920000149052_1_Domain_4 (1464, 1624)

TERERLLLAFQASGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPTLPGPGGTPPAKAQHLLQQVLDRFYPRRYRNGAPPEQL------------
-----------------------RHLADMMATKWAALQGCSPPECIRIYLTVARKWPLFG
AKLFAAQPAQ-LSSKENTVVWIAVNEDGVSILDHRTMQVNITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKTRIDKLTFRMPAPKITETTLMMASYMNHCSATV-NLSA--------
--KLPAARQPRDLDGQ-FFASVSCTKGSALL-

------------------------------------------------------------
----------------------------------MSETEVESGTCVNWQKRCLTLETQLF
QFRLQASKIRKLLADK---MQELEQRLLEAEHRAENAETQVCTMEEKIKLVNVKSIEPEG
KFHQKYQELLETIRGKEEIISQLQTQVEKQKQLRVQDAKTVQEKAAKIKEWVTMKLGELE
-MENRHLKNYNQRLVEQVRALRAALG----------------------------------
--------------------------------------------------------DLSM
------------------------------VLPGELLWSFQGKSKNNSVVSEIGIHQEGQ
RGVMEGNITSQ----------------------AQTAAVS--LPSSVTQQ-DKDLIPKVS
NTLKGS--------GRIICGEIPETKAPQLSPRDT--------------------VGL--
-----QKSAYLGEI-------------LGGFQ-RGMPIKLSFPTKERVLGSSMTLPKDRA
FRNPRDSIQLAKRRYSQPQMRTECFNHMLSIEISTLQTSQIHTLPMKE-TNIDQKKRKES
EKMDTEEPSSDKKEVKASESTS--KLE-EELEKSSTKEMEMGNKPPTPPLHQFPSWEH-C
VYEPSRNSLKMQILANRDWGGSCS--------SSSMSFTSP-GSFSKLVNQNFHVPVYTT
LKGRATQISTMPFLDESSGSEDDCSSQTSFQTSVTCVESRKANVPGSPRAIKRG-VS-IS
SLSSESDYAIPPDAYSLDSDYSEPEYKVQRTSIYSID-----GLGSHGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
DSRVKTWKRRWFVLRHRQIMYYKSPSDVIQKPQGQVELNSHCH-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
HAIGSPGLPQSGAKPIVRGWLTKVKHGHSKLVWCSLIGRTFYYYRSHEDKYPLGCLPIRG
ALIEEVDRSCDSDEDYEGTGGMRRLLSSHCTLVIHPPEHSPTYLLIGSKHEKDTWLYHLT
VVAGSN--SAKVGTAYEQLIGKLMDEE-GDPGSPLWKHPMLCYSKDGLCTPLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSELYCQLIKQTSC
HP--PQRHSFLQQCWQLLALCAPLFLPQHHFLWYIKQRLQRHADPR--SETGQYATYCQR
AVRRTLEAGEREAKPSRLEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1463)

ILLRNPYHHSLPFSIPVHFVNGTYQVIGFDGSSTVDEF
LHQLNQEMGMRKVSHSGFSLFTDDPSGKDLEHYLQGSIKICDAISKWEQSLRELHPRKSE
GSNRIVKLIYKNRLYFRHQVKG

PF00373 // ENSGT00920000149052_1_Domain_4 (1463, 1624)

ETEQERLLLAFQVSNEITAGRFPVNKELALEMAALMA-
QMEYGDLEKPNLPGTMGTAPAKVQYLLQLVLERFYPKRYKCGAPSEQL------------
-----------------------RYLADTLASKWTTLQGCSPTECIRIYLTVARKWSLFG
AKLFAAQTTQLSTKG-NPLVWIAVNEDGVSILDHNTMQVQAIYPYSLVMTFGGYQDDFM-
-IVIRPVPDKSSDKGNTEKLIFQMALHKIAELTFMMASYMNHCSTISASSPN--------
---TPPIRHFQGKDGKQSLASASQNTKGPTLL

------------------------------------------------------------
----------------------------------MAELKVDARASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSGG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSWKLLVPPHGAAEQDSVPSEPGIQPMGQ
N----------SGSQA---------------QG-LKTAVLA--PSPDALQ-SKDSVSEAA
SPLEDS------SSSTVHSGEMVEAKPLQPHLGREGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLAKRHHSQPQVGRGHFDRVLSIEIGAFSALHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNEERES---------PKALAAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALLRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NPPGACQLWELDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELKVDTPAGVDWQKRCLTLETQLF
RFRLQASKIRELLADK------------------------VGVMEEKVKLSNLRDVDSTG
SLPQKYQELLKAMQGKVELIDQLEAQLEKQKQMRAEEAKMVQKKAAKIKEWVALKLTELE
-MENQHLRSCNQHLVEQVGALQAALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APPGKLLVIPKGSPELDSVPTESGARPVGQ
D----------SGSQA---------------LD-LKGAIPV--LSVDAPE-STGFLSQAR
DSVEDS------CSSTFHPVEVADTRVLQSHLESEHF---------------PSQLCV-K
PSTPGY-----GEG-------------TVTAQ-ERVLPGVKTSVREGGPGSSLTLPKVRA
SSTPQVSIQVAKRHHSQPHVGLGHFERAVNTETGSLSAFRPSGLSKLD-TC--ADFWEEP
EKMEMGELPPAGKEEERDS---------LKVPSTELEEVKLGNKPPTPPLHRFPSWES-R
IYAVATSGMQVSDVSPRSSASCCA--------SSPPALVCP-GPFSGLAYKNITVPVYTT
LKGKATQISSVPFMDESSGSDDDCSSLASFRMSVPCSECRKNSGLGSPRAIKRG-VS-VS
SLSSEGDYAIPPDACSLDSDYSEPEHKMQRTSCYSTE-----------EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSSYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPNDVILKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLMADSPSLLEEWIRALQSLLKV
QATRPPALSQGGTKPAVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-TGTRRLLSSHCTLVIHPPEHSPTYLLIGTKPEKDTWLYHLT
VAAGGS--SGKVGTAYEQLIGKLMDGE-GDPDSPLWRHPTLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEATSVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTVLQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSHLEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVGEF
LQRLNQETGMRKSSQSGFALLTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRIVKLMYKNRLHFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAYQTNGEIVAGRFPVSKELALEMAGLMA-
QIEYGDMEKPILPGPGGTPPAKAQHLLQQVLDRFYPRHYRHGAPPEQL------------
-----------------------RHLANMLATKWTSLQGRSLAEYTRTYLTVARKWPLFG
AKLFAAQPAQLSSKE-NNLVWIAVNEDGVSILDHHTLQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSTPDQSSGKGHTDKLIFRMAVPKIAEATFIMASYMNHCSATV-DSPT--------
--SRPAARLPRELDGRQRFASVCCATKEPTLL

------------------------------------------------------------
----------------------------------MAELKVETRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDLGG
SLHQKYQELLKAMQSKDELISQLEAQLEKQKQMRAEEAKVVQEKAAKIKEWVTLKLAELE
-MENQHLKSSNQHLAEQVGVLQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVATQEIPEQDSGPSGPGTQPIGQ
D----------SGPQA---------------QGALKATMAA--PSPDALQ-SKDSV-SPG
ISLEDS------SPIVVHPGEISDSKALPLHLG-EGS---------------PRRLCM-K
PRTHRHGSASWGEG-------------LVIAQ-GGTLPGTKNSAREGSPGCSLTLPKVRV
PSTPRDSIQLAKRHHSQPQVGPGHFNHVVSIEIGTLSALHPSSLPEVE-AR--AELREEP
ENVEMEEQPPMAKEKERES---------PKAPRAELEEVDLGNKPPTPPLHRFPSWES-R
IYAVAMAGMRLSDASSRTNVT--------CCASSPPALASP-GPFSGLVYKNVTVPVYTA
LKGRATQISSVPFMDESSGSDDDCSSQASFRSSVPCSESRKTSGLGSPRAIKR-GVS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYS-I--EG--PGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGVVELNSHCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPGLLEEWIRVLQSLLRV
QAVGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGHLPVRD
ARIEEVDRSCDSDEDYEA-GGSRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SARVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLV-QCWQLLALCTPLFLPQHHFLWYVKQQFQRHADPR--NETGQYATYCQR
AVERTLQAGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1463)

ILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLPGGVKICDAISKWEQALKELHSGKAE
GGTRVVKLMYKNRLYFRSQVKG

PF00373 // ENSGT00920000149052_1_Domain_4 (1463, 1624)

ETERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPSPPGPGSPLPAKVQHHLQHVLDRFYPRRYRHGAPSEQL------------
-----------------------RHLADLLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAARPAQLSSKE-STLVWIAVNEDGVSILDHNTMQVHVTYPYSSVMTFGGCRDDFM-
-LVIRSIPDQGSGKGHIEKLLFQMAAPKIAEATFIMASYMNHCSTTV-NTPP--------
--NPPAAHQLWELDGQQFFASVPCAARGPTLL

------------------------------------------------------------
----------------------------------MAELQVDTQASVDWQKRCLTLETQLF
RFRLQAGKIRELLADK---MQELEQRLLEAEERAEKAETQVGVMEEKVKLSNLRNVDSAG
SLHRKYQELLKAMQGKVELISQLEAQLEKEKQMRAEEAKTVQKKAAKIKEWVALKLTELE
-MENQHLKSCNQHLMEQVGALQAALE----------------------------------
--------------------------------------------------------ALQV
------------------------------VPRGKLLATPEGAPELESVPAEPGAQPVGQ
D----------SGSQA---------------LD-LKVAVPA--PSLDAAE-SRGFLSEAR
SPVEGS------SSSTFHPGETAEAKVLQPHVESKHF---------------PSQLCT-K
PGASRRGSASWGTG-------------LAAAQ-ERVLPGLKASSGEGGPGSSLTLPKVRA
PGSPQGSIQAARRHHSQPHVGPGHLEDVVNVETGALSTLHPPGHLKLE-TC--ADFQEEP
EKMEMEELLPARKEGERES---------LKAPSTKLEEVKLGSKPPTPPLHRFPSWES-R
IYAVATSGMQVSDESPRSGAAGCA--------SGPPALVCP-GPFSGLVCKNVSVPVYAA
LQGKATQISSVPFVDESSGSDDDCSSQASFRMSVPCLECRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKMQRTSCYSAE---G-------DSL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPNDVILKPQGQVDLNCHCQ-----------------
------------------VVRGEGAQTFQLISEKKTYYLMADSPSLLEEWIRALQSLLKV
QATGPPALPQGGTKPAVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SVKVGTAYEQLIGKLMDAEGGDPDSPLWKHPILCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTVLQVCLVHPELQSEIYCQLMKQTSC
RP--PQKSSLM-QCWQLLALCAPLFLPQQHFLWYVKQQLQRHADPR--NESGQYATYCQR
AVERTLQAGEREARPSHMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSHSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQALKELHPGKSE
GGTRIVKLLYKNRLHFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAYQTNGEIVAGRFPVSKELALEMAGLMA-
QIEYGDMEKPLLPGPGGTPPSKAQHLLQQVLDRFYPRHYRLGATPEQL------------
-----------------------RLLANTLATRWASLQGRSLAEYTRTYLTVARKWPLFG
AKLFAAQPAQLSSKE-STPVWIAVNEDGVSILNHHTMQVRATYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKGHIDKLIFRMAAPKIAEATFIMASYMNHCSATA-GSPP--------
--SLPAAHAPRKLDG-QFCASASCATKGPTLL

------------------------------------------------------------
----------------------------------MAELTVETRASVDWQKRCLALETQLF
RFRLQASKIRELLADKAEQMQELEQRLLDAEQRAENAETQVGVMEEKVKLSNLMNVDSAG
SLHRKYQELLKAMQGKDELISELEAQLEKQKQMRAEEAKVVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQHLVEQVGALQRAVE----------------------------------
--------------------------------------------------------ALQM
------------------------------SPSGKLLVAPQGTTEQESVPSGPGTQPAGQ
D----------SGPLA---------------QGALKAAIPA--PSPGALQ-SKDSVPKAG
SPMEDS------SSQTVHPGATSEAKTLPLHLGRQGS---------------PGQLCL-R
PRTPRHALASWGEG-------------LVTAQ-GGTLPRTKTSAKEGGPGCSLTLPKARA
PSTLRDSIQLAKRHHSQPQAGPGHFSHVVRIEVGTLSAFHPHSLPKGV-VR--AKLREEP
EKMEMEEQPPVGEKE---------------AQGTELEEVDLENKPPTPPLHRFPSWES-R
IYAVATSGMRLSEVPVRSNAT--------CCASSPPALASP-GPFSGLVYKNVAVPVYTA
LKGKATQISTVPFVDESSGSDDDCSSQASFRTSLPCSESRKTSGLGSPRAIKR-GVS-VS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYS-T--DG--LGPGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QAIGPPALPQGGTKPTVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGRLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHYTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEAVKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSEIYCQLMKQISC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1463)

ILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPAGRDLEHCLQGSVKICDAISKWEQALKELHTGKSE
GGTRVVKLIYKNRLYFRSQVKG

PF00373 // ENSGT00920000149052_1_Domain_4 (1463, 1624)

ETERERLLLASQTNGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPILPGPGGTPSAKAQHHLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADQLTTKWAALQGCSSPECVRIYLTVARKWPLFG
AKLFAAQPAQLSSKE-SALVWIAVNEDGVSILDHNTMQLHVTYPYSSVMTFGGCRDDFM-
-LVIRSVPDQSSGKGHVEKLIFRMAAPKIAEVTLILASYMNHCSTTV-NPPS--------
--TPAAACQPWELDGRQFFASVPCAAKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVEV-ASIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSNLKSVDSTG
TLHQKYQELLRAVQGKDELISQLQAQLEKQKQTRAEEAKIVQEKAAKIKEWVTVKLAELE
-MENQQLKTCNQQLVEQVAALQDALE----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEELLVVPEGTPERDPVPSGPSDQPVEQ
D----------SNPHT---------------QI-LKVAVPT--PSLGTLQ-SRDSLSEAR
SLEDLRF-------SMVHPGETAEAKTLQSHLQKEGS---------------PSQLCM-K
PGNPKHGSASYRES-------------LVTAQ-GGTFPGTKTSAREGGPGSSLTLPKVRA
PSIPRDSFQVAKRHHSQPQVGPGHCDHVVSIEIGALSALHSPGSSKSE-AR--AKVREEA
EKMEMEALPPSGKQEERES---------LKSRRGELEDVELENKPPTPPLHRFPSWES-R
IYAMATSGMQLSEVSSRRSNAACY-------ASGPSALAFP-GAFSGLVYKNVTVPVYTA
LKGKATQISNVPFVDESSGSDDDCGSQASFRMSVPCSEYRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVREEEAQTFQLISGNKTYYLTAESPSLLEEWIRVLQSLLKV
QVTGPPALHQGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVQD
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--NAKVGTVYEQLIGKLMDGE-GNPDSPLWRHPMLCYSQEGLCASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQISC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYAIYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAFQASGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPTLPGPGGTPPTKAQHLLQQVLDRFYPRRYRNGAPPEQL------------
-----------------------RHLADMMATKWAALQGCSPPECIRIYLTVARKWPLFG
AKLFAAQPAQ-LSPKENTVVWIAVNEDGVSILDHRTMQVNITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKTRIDKLTFRMPAPKITETTLMMASYMNHCSATV-NLSA--------
--KLPAARQPRDLDGQ-FFASVSCTKGSALL-

------------------------------------------------------------
----------------------------------MAELKVDVRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSPG
SLHQKYQELLKAMQGKDELIRQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLVELE
-MENQHLKSCNQCLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVSPHGAAEQDSVPSEPGIQPVGQ
D----------SGSQA---------------QG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSTVHSGEVIEAKPLQPHLGREGS---------------PHQPCM-K
LRTFRCGSAFWGER-------------LVMAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PSTPRDSIQLAKRHHSQPQVGHGHFDHVVSIEIGTFSALHPSGLPELE-AR--TGYRDEP
EKMEMEEPPPAGKKEERES---------PKALGAEPEEVEPGNKPPTPPLHQLPPWES-R
IYAVATSGMRLSDTSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPCSESRKTSGLGSPRAFKRG-VS-MS
SLSSEGDYAIPPDACSLDGDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRMKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALPQGGAKPTVKGWLTKVKHGHSKLVWCALVGKNFYYYRSHEDKRPLGCLPVQD
AHIEEVDRSCDSDEDYEA-GGTRQLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPESPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRMNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAQKELHPRKSE
GGTRVVKLMYKNRLYFRGQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREILAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKSHIEKLIFRMAAAKIAEATFIMASYMNHCSTTV-NPPT--------
--HPPGARQLWELDGRQFFASVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELKVETRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSAG
SLHRKYQELLKAMQSKDELISQLEAQLEKQKQMRAEEAKVVQEKAAKIKEWVTLKLAELE
-MENQHLRSSNQQLVEQVGALQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVAPQETPEQDSSSSGPGTQPTGQ
D----------RGPQA---------------QGALKAAMPA--PSTGALQ-SKDCVPKAG
ISLEDS------SSIMVHPGEISEAKTFPPRLGREGS---------------PRRLCV-K
SRTHRHGSASWGEG-------------LVIAQ-GGTLPGTKNSAREAGPGCSLTLPKVRA
PSNPRDSIQLAKRHHSQPQVGPGPFNHVVSIEVGTLSALHPSSLPEVE-AR--AELREEP
ENMEMEEQPPAGRKEERKS---------PKAPRAEPEEVDLGNKPPTPPLHRFPSWES-R
IYAVAMAGMRLSDVSPRTIAT--------CCASSPPALASP-GPFSGLVYKNVTVPVYTA
LKGRATQISTVPFVDESSGSDDDCSSQASFRTSVPCSESRKTSGLGSPRAIKR-GVS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYS-T--EG--LGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSL

ENSGT00920000149052_1_Linker_0_1 (1018, 1038)

LKV
QAIGPLALPQGGIKPTV

PF00169 // ENSGT00920000149052_1_Domain_1 (1038, 1140)

KGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGHLPVRD
ARIEEVDRSCDSDEDYEA-GGTRQLLSSHCTLVIHPREHSPTYLLIGTKHEKDTWLYHL

ENSGT00920000149052_1_Linker_1_3 (1140, 1231)

T
VAAGGS--SARVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASIDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYIKQQLQRHADPT--NETGQYATYCQR
AVERTLQVGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFASGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSIKICDAISKWEQALKELHSGKAE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPTPPGPGSTPPAKLQHHLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADLLTTKWTALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHSTMHVHVTYPYSSVMTFGGCRDDFM-
-LVIRSILDQSSGKGHTEKLLFRMAAPKIAEATFIMASYMNHCSPTV-NPPT--------
--NPPAARQLRELDRQQFFASVPCAARGPTLL

------------------------------------------------------------
------------------------APRNSEVGLIMAELKVEPRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQXXXXXXXXXXXXXXXXXXXVSVMEEKVKLSNLKNVDSAG
SLHRKYQELLKALQGKDELISQLEAQLEKQKRMRAEEAKLVQEKAAKIKEWVTLKLAELE
-TENQHLKGCNEHLVEQVGILQDALE----------------------------------
--------------------------------------------------------ALQV
------------------------------APVGKLPVGPQEAPEQNAVTSGPGSQLTGQ
D----------SHPQT---------------ESSLKVAVPA--PSPGALA-NKTSVPKAG
NPLEDS------ESNLAQSGERAEAKTPQIHLRREDS---------------PGQVSG-K
PHIPRCGSASWDEG-------------LLSAQ-GRMLPETKSSTREGGPGSSLTLPKARA
PSILRDSIQLAKRHHSQPQVGPGHFDHVVSIESGALSALHPTSLPKVK-TE--TELWGEP
EKMEMEEPPPASKKEGLES---------LKIPGPDPEEAELGNKPPTPPLHRFPSWES-R
IYAVATLGMQLSEAAPKSNTANYA--------SSPPALASL-GPFSGLVYRNITVPVYTA
LKGRATQISTMPFVDESSGSDDDCSSQASFRNSVPCSESRKTGGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGLES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPNDVIRKPQGQVELNSRCQ-----------------
------------------IIRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

KV
QAIGPPALAQGSTK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PTVKGWLTKVKHGHSKLVWCALIGRTFYYYRSHEDKRPLGRLPVRD
ARIEEVDRSCDSDEDYEA-GGTGRWLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAA

ENSGT00920000149052_1_Linker_1_3 (1144, 1227)

GGT--SAKVGTAYEQLIRKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTKALKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLVHPELQSEIYCQLMKQTCC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLKTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQETGMRKCSHSGFSLFTDDPSGRDVEHCLQGTVKICDAISKWEQALKELHPGKSE
GGTRIVKLMCKNRLYFRSQVKGETERERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPSPPGSGGTPPAKSQHLLQQVLDKFYPQRYRHGVPPEQL------------
------------------------HLTDMLATKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFTAQPAQMSFKE-NIPVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGYRDDFM-
-LVIRSFPDQISGRSHIEKLIFRMAAPKIAEATLIMASYMNYCSATV-NPPT--------
--SPSASRQPWELDGRQFFASIPRDTKGPMLL

------------------------------------------------------------
----------------------------------MAEVKVEVRSSVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLMEAEQRAENAETQVGMMEEKVRLSNLKNVDSTG
SLHPKYQELLKAMQEKDELISQLEAELEKQKQMRADEAKIVQEKAAKIKEWVTVKLAELE
-IENQHLKSCNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------TPSEKLLVDPEGTPEQDSVPSGPGAQPVGQ
D----------SDAQT---------------QL-LNVVVPV--PSLSALQ-SKDSASEAR
SLEDLSSS--MAKHSMGHPGEIAEAKTLQSHLGREGS---------------FSQLCM-E
SGSPRCGSSSFREG-------------LVTTQ-RGTLPGTKASAREGGPGSSLTLPKVRA
PSIPRDSFQVARRHHSQPQVGPGHFDHVVNIKIGTLPALHPSGHSKSK-VR--AEVWEEA
EKMEMEAPPPTGKQEEEES---------LKPSRTELEEVDLENKPPTPPLHRFPSWES-R
IYAMATSGMQLSDVSSRNNTTCCGDVKGLNVLGDPAALASP-GAFSGLVYKNVTVPVYTT
LKGRATQISSVPFVDESSGSDDDCGSQASFWMSAPCSECKKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYS-------------ESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISENKTYYLTADSPSLLEEWIRVLQSLLKV
QVTGPPALHPGGTKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRSHEDKRPLGYLPVQG
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMEGE-GDPDSPLWRHPMLCYSKDGLCTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPK--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSYSGFALFTDDPSGRNLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLASQTSAEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPILPGPGGIPPAKAQHLLQQVLDKFYPRRYKNGAPPEQL------------
-----------------------RHLADTLATKWAALQGCSPSECIRIYLTVARKWPLFG
AKLFAAQPAQLS--SKNTLVWIAVNEDGVSILDHHTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQGSGKGHIDKLIFRMPAPKIAETTFIMASYMNHCSAPV-NLST--------
--KLPAARQPWELDGQQFFASVSCTSKGPASL

------------------------------------------------------------
----------------------------------MAELKVEAPASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTIQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQRLVEQVGSLQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPHGAAEQDSVPSEPGIQPMGQ
D----------SGSQA---------------QG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPLEDS------SSSTVHSGETVEAKPLQPHLGRESP---------------PHQPCM-K
LLTFRCSSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNEERES---------PKALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALVSP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSL

ENSGT00920000149052_1_Linker_0_1 (1018, 1038)

LKV
QATGPPALLRGGTKPTV

PF00169 // ENSGT00920000149052_1_Domain_1 (1038, 1140)

KGWLTKVKHGHSKVVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPTEHSPTYLLIGTKHEKDTWLYHL

ENSGT00920000149052_1_Linker_1_3 (1140, 1231)

T
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLRTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVAKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAVLMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCTTTV-NPPT--------
--NPPGACQLWELDGRQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELKVDMRASIDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSPG
SLHQKYQELLKAMQGKDELIRQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQCLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPHGAAEQDSVPSEPGIQPVGQ
D----------SGSQA---------------QG-LKAAVLA--PSPSALQ-SKDSVSEAA
SPLEDS------SSGTVHSGEVIEAKPLQPHLGRESS---------------PHQPCM-K
LRTFRCGSASWGEH-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PSTPRDSIQLAKRHHSQPQVGHGHFDHVVSIEIGTFSALHPSGLPELE-AR--AGYRDEP
EKMEMEEPPPAGKKEERES---------PKALGAEPEEVEPGNKPPTPPLHQLPPWES-R
IYAVATSGMRLSDASPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRISVPGSESRKTSGLGSPRAFKRG-VS-MS
SLSSEGDYAIPPDACSLDGDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRMKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSL

ENSGT00920000149052_1_Linker_0_1 (1018, 1038)

LKV
QATGPPALPQGGTKPTV

PF00169 // ENSGT00920000149052_1_Domain_1 (1038, 1140)

KGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEV-GGTRRLLSSHCTLVIHPLEQSPTYLLIGTKHEKDTWLYHL

ENSGT00920000149052_1_Linker_1_3 (1140, 1231)

T
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQAGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRMNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAQKELHPRKPE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREILAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKSQVEKLIFRMAAAKIAEATFIMASYMNHCSTTV-NPPT--------
--HPPGARQLWELDRRQFFASVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAELAVENGSCTDWQKRCIALESQLF
KFRLQASKIRELLAE---KMQELEQRVMEAEQRAEDAEKQVRIMEEEIKLANMKTGESDS
ALYRKYQELMGTVQGKEDLINRLETQLAKQKQLRTEELKIVQEKAAKIKEWVTFKLRELE
-LENYHLKNCNQRLTEQIEALQDTLQGITLFGCHKSSSLISH-LGLNMG--PCFETGTAH
GELWSSGLEPSALGNEQFHPVLLSHFSHYARLNPEAPAEG-------QIFLLA---TLTI
RASSASCHIHCN-------------S----LKSRAPQASLPEKIDQKSMFLAPGFRQLCQ
TRPTKRVFSTTSIVLANDTFTEDGEVPTTW------------------------------
------------------------------------------------------------
------------------IPLPQTAGPPLAMSTSAATAGSICPGRECGLGSSMTFPKTRT
PNAPRDSIQLAKRHYSQPQSGAGSFHRVMSLEASTFQPI---PVCHGPVEETDIDDYRVL
EKMETEGGLVREEAGTYEI--KHLTAK-REAVSSEAGMLDPGCKPPTPPLHRFPSWES-R
IYDMAKSGMRLSEAAAVNDASSCF--------SNF-SRSAS-GPFTGFIHRNMAVPVYAM
LKGKATQISNVPFLDESSGSDDDCGSHASFRNSTAGSENRKASMPGSPRAVKR-GVS-MS
SLSSESDYAIPPDAYSLDGDYSEPEHKLQRTSSYSTD------GGICTES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

MEKSGYLLKM
GSQVKMWKRRWFVLRNGQIMYYKSPSDVIRKPQGQMELNSSCQ-----------------
------------------IVRGEGSQTFQLMTEKRTYFLTADSPNILEEWIHVLQSIL

ENSGT00920000149052_1_Linker_0_1 (1019, 1035)

RV
QVTSPVGVPHSDAK

PF00169 // ENSGT00920000149052_1_Domain_1 (1035, 1144)

PTVKGWLTKVKHGHSKLVWCALIGKNFYYYRNHEDKCPLGHLPLRE
SKVEEVDRSCDSDEDYEATGG--GLLSSHCTLVIHPQDQSPTYLLIRTKHEKNTWLYHLT
VAA

ENSGT00920000149052_1_Linker_1_3 (1144, 1227)

GSS--NATVGTSYEQLIGKLLDAE-GDPNSPLWKHPMLCYSKDGLHTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAPSV

PF00784 // ENSGT00920000149052_1_Domain_3 (1227, 1344)

DYHVSLAQTALQVCLTHTELQNEIYCQLVKQTSC
RQ--PQNHSVI-QCWQLLALCAPLFLPQHHFLWYIKQHFQRHADPR--SEIGKYAIYCQR
SVDRTVQTGEREAKPSRMEIVSILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEF
IQRLNQETGMRKPSHMGFSLFTDDPSGRDLEHCLQGNIKICDVISKWEQALKELHPGKYE
GGTRIVKLTYKNRLYFRSQAKGETDRERLLLAFQVSNEIASGRFPVNKELALEMVALMA-
QVEYGDLDRPGSSSPGGTSQPKMQHLLHQVLDKFYPKRYKQNIAPEQL------------
-----------------------KQLADRLATKWMVLQGCSPPECVRIYLTVARKWPLFG
TKMFAAKPILPSSLE-DCPVWIAVNEDGISILDYNTMHLKLSYSYSSVLTFGGCRDDFM-
-IVVSQIKERSSGKNSTEKLLFAMAIPKIVEATLLIASYINYRSTASLLPSTQPSR----
--NATPANKLWETESRCFFPSKPRSTKGPTLL

------------------------------------------------------------
----------------------------------MAEVKLETRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLQSVDSAG
SLHRKYQALLKAMQGKDELISQLEAQLEKQKQIRAEEAKIVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------GLQM
------------------------------APSGKLLGDPRGAPEEESVSSGPGTQTVGQ
D----------SGPQV---------------QD-LKLDLSA--SSPDALR-SKDSVSKTG
NPLEDS------GSSVVHSGEIAEAKTPQPHLEREGC---------------PHQLSM-K
TLTPRHGSASWGEG-------------LVTAQ-GVMLPGTKTSAREGGPGSSLTLPKVRA
PRTPRDSIQVAKRHHSQPQAGPGHFHHVVSIEIGAFSAIQPSGLHKLE-AQ--AESREEP
EQMEMEEPPPARKE-ERKS---------PKTLQAELEEVELGKKPPTPPLHRFPSWES-R
IYAVATSGMQLSDVPPKSNAACCA--------SSPPARASP-GPFSGLIYKNLTVPVYTA
LKGRATQISSVPFVEDSSGSDDDCSSQASFRTSVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGRESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1019)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRQPQGQVDLNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWVRVLQSLLKV
QTTGPPILPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGRLPVRD
ARIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKETWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPVWRHPMLCYSKDGLHASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYH

PF00784 // ENSGT00920000149052_1_Domain_3 (1230, 1343)

VSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PPKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQSGEREARPSRMEVVS

ENSGT00920000149052_1_Linker_3_4 (1343, 1465)

ILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

DRERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTPSAKVQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAPMAPKE-NSLVWIAVNEDGVSVLDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDQSSGKIHIEKLIFQMAAPKIAEATFIMASYMNHCSATV-NPST--------
--NPPVARQLWDLDGQQLFASVPRATKGPTLL

------------------------------------------------------------
----------------------------------MAELTVETRTSVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLMNVDSAG
SLHRKYQELLKAMQGKDELISELEAQLEKQKQMRAEEAKVVQEKAAKIKEWVTLKLAELE
-MENQHLKSCNQHLVEQVGALQCALE----------------------------------
--------------------------------------------------------ALQM
------------------------------SPSGKLLVAPQGTTERESVPSGPGAQPVGQ
D----------SGPPA---------------QGALKAAIPA--PFPGALQ-SKDSVPKAG
SPVEDS------SSRTVHPGATSEAKTLPLHLGRQGS---------------PGQLCL-T
PRTPRHGLASWGEG-------------LVTAQ-GGTLPRTKTSAKEGGPGCSLTLPKARA
PSTLRDSIQLAKRHHSQPQAGPGHFSHVVCIEVGTLSAFHPPSLPKGV-VR--AEPREEP
EKMEMEEQPPVGKKE---------------AQGTELEEVDLENKPPTPPLHRFPSWVR-S
LCLPPTP-----------------------SWVIPPALASP-GPFSGLVYKNVTVPVYTA
LKGKATQISTVPFVDESSGSDDDCSSQASFRTSVPCSESRKTSGLGSPRAIKR-GVS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYS-T--DG--LGPGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QAIGPPALPQGGTKPTVKGWLTKVKHGHSKLVWCALVGRTFYYYRSHEDKRPLGRLPVRN
AHIEEVDRSCDSDEDYEA-GGTRRLLSSHYTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLFTSLTTLPSEAL
QTEAVKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLAHPELQSEIYCQLMKQACC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQEMGMRKSSRSGFALFTDDPAGRDLEHCLQGSAKICDAISKWEQALKELHTGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLASQTNGEIVAGRFPVNKELALEMAALMA-
QVEYGDLERPILPGPGGTPSAKAQHHLQQVLDRFYPRRYRHGAAPEQL------------
-----------------------RHLADQLTTKWAALQGCSSPECIRIYLTVARKWPLFG
AKLFAAQPAQLSSKE-SALVWIAVNEDGVSILDHNTMQLHVTYPYSSVMTFGGCRDDFM-
-LVIRSLPDQSSGKGHVEKLIFRMAAPKIAEVTFILASYMNHCSAAV-NPPT--------
--TPAAACQPWELDGRQFFASVPCGAKGPTLL

-------------------------------------------------------TTQGQ
RRTRAEGAAVRGARWGRPRARQTA-PWNPKVDSIMAELVVETRTSVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVSVMEEKVKLSNLNNVDSSG
SLYQKYQEMLKALQGKDELISQLEAQLEKQKQMRAEEAKIVQEKAAKIKEWVTLKLAELE
-IENQHLKSCNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVASQETPGQDAVSSRPRAQLMGR
D----------SGPHA---------------QGALKAVLPA--PSPGSLQ-SKDCAPKVG
SSLEES------SSIMVHPGEISEAKTLPPRLGREGA---------------PSQLCM-K
TQSPRHHLASWDEG-------------LVTAE-GGTVPGTKTSTREGGPGCSLTLPKVRA
PSTPRDSVQLARRHHSQPQVGPGHFNHVVSIEIGTLSALCPSGLPKVE-AR--VEVREEP
EKMEMEEPPPAWRKEEREN---------PKAPGAELEEVDLGSKPPTPPLHRFPSWXX-X
XXXXXXXXXXXXX-------XXXXXX-XXXXXSKPPALVSP-GPFSGLVYKNGTVPVYTS
LKGRATQISTMPFVDESSGSDDDCSSQASFRTSFTCPEPRKTSGLGSPRAIKRG-VS-MS
SLSSESDYAIPPDACSLDSDYSEPEHKLQRTSSYS-M--DG--LGLGGES

PF00169 // ENSGT00920000149052_1_Domain_0 (891, 1019)

LEKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVELNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPNLLEEWIRALQSLLKV
QATGPPVLPQGGTKPTVRGWLTKVKHGHSKLVWCALIGRTFYYYRSHEDKRPLGHLPVRD
ARIEEVDRSXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWKHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASV

PF00784 // ENSGT00920000149052_1_Domain_2 (1227, 1282)

DYHVSLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QGWQLLALCAPF-LPQHXXXXXXXXXXXXXXXXX--XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVGFDGSSTVDEF
LQQLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSVKXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
XVEYGDLERPIPPGSGGTPPSKAQHHLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLTDQLTTKWAALQGCSPPECIRIYLXXXXXXXXXX
XXXXXXXPVQLFSKE-NTLVWIAVNEDGVSILDHNTMQVHVTYPYSSLMTFGGCRDDFM-
-LVIRSIPDQSSGKGHVEKLIFRMAVPKIAEATFIMASYMNHCSATV-NAPT--------
--NLPAARKPWELDGQQFFAPVPCATKRPTLL

MGRRKAR--PGFVQRARGHPSRSSLAPPRPAPRDPCCRRAESRQPP----GTPARATQGR
RRRRPEGARVPGARRGRPRARWRAPRNNPEVDSIMAELKVDARASVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSAG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQHLVEQVGALQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSRKLLVPPHGAAEQDSVPSEPGIQPTGQ
N----------SGSQA---------------EG-LKAAVLA--PSPGALQ-SKDSVSEAA
SPSEDS------SSSTVHSGEMVEAKPLQPHLGREGP---------------PHQPCM-K
LRTFRCGSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLTKRHHSQPQVGHGHFDRVVSIEIGAFSALHPSGLPELE-SR--ARYREEP
EKMEMEEPPPAGKNGERES---------PQALGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALASP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFRMSVPCSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQNLLKV
QATGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPAEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQFLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPRKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHVTYPYSSVTTFGGCRDDFM-
-LVIRSIPDKTSGKSHIEKLIFQMAAPKIAEATFIMASYMNHCSTTV-NPPT--------
--NLPGACQLWELDGQQFFSSVSCATKGPTLL

------------------------------------------------------------
----------------------------------MAEVKVDARASIDWQKRCLALETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGMMEERVKLSSLKNVSSAG
SLHQKYQELLRATQDKDQLIHQLGAQLDKQKQMRAEEAKIVQEKAAKIKEWVTVKLAELE
-TENQRLKSCNQHLAEQVGALQDALE----------------------------------
--------------------------------------------------------ALQV
------------------------------APSEKLLVAHEGTAERTCVPPGPGAPPMGK
G----------GGAKT---------------QE-LKTAVPG--SPLGTPQ-SKNSMSEAQ
SLEDS-------NSSLVHPGERAEVKTVQPHRGREGS---------------PNQLRM-K
PRTPRCGSASYKEG-------------LAMAQ-GGTLPGTKTSAREGGPGSSLTLPKVRA
PSVLRDSFQVAKRHHSQPQVGPGHLDHVVSIEIGALSALHPSRLSKLE-AR--AKVREEP
EKMEME-PPPGGRQEEEES---------LKAPRAEPEDVELENKPPTPPLHRFPSWES-R
IYAMATSGMQLSDMSPRSNAACCA--------SSPASLTSP-GPFSGLVYKNVTVPVYAA
LKGRATQISSVPFVDEASSSDDDCGSQASFRLSVPCSECRRTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSTYSTD-----GLGLSG----

PF00169 // ENSGT00920000149052_1_Domain_0 (893, 1018)

KSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKNPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKV
QATGPPALHHGGAKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGHLPVRD
ARIEEVDRSCDSDEDYEA-GGAGRLRSSHCTLVIQPPEHSPSYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTVYEQLIGKLMDGE-GDPGKQGK------------------------
VTKGRLCLQS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVRQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLASQISGEIVAGRFPVTKELALEMAALMA-
QVEYGDVEKPILPGPGGTPSAKTQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADTLATKWAALQGCSPSECIRIYLTVGRKWPFFG
AKLFAAQPAQLSAKE-NALVWIAVNEDGVSILDHHTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSAPDQSSGKGHIDKLIFRMAAPKIAEATFTMASYMNHCAAPT-NLPA--------
--KLPTARQPWELDGRQFFASVSCTKG-PAL-

------------------------------------------------------------
----------------------------------MAEVKVEV-AGIDWQKRCLSLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKIKLSSLKSVDSPG
SLHQRYQELLKAVQSKDELIGQLEAQLEKQKQTRAEEARIVQEKAAKIKEWVTVKLAELE
-TENEHLKACNQQLAEQVEALQDALE----------------------------------
--------------------------------------------------------DLRM
------------------------------TPSEKLLVDPEGTPEGSPVPSGPGAQPVEQ
D----------SNPHT---------------QI-LKVAVPA--PALGPRQ-NKDSVSEAR
SLEDLSF-------SMAHPGEIAEAKVLKSHPQREGS---------------PSQLFV-E
PSSPKHGSASYRAD-------------LVTAR-GGTFPGTKISAREGGPGSSLTLPKARA
PSNPQDSIQAAKRHHSQPQVGPGHFDHVVSIKIGALSALHSPGFSKAE-AR--AKAREEA
EKMEMEEPPPTGTQEEGER---------PKPPRAELQEVELESKPPTPPLHRFPSWES-R
IYAMATSGMQLS-DVSSRSNAACC-------ASGPPALALP-GAFSGLVYKNVTVPVYTA
LKGKATQISSVPFVDESSGSDDDCGSQASFRMSVPCSEYRKTGGLASPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTE-----G-----EAL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSHCQ-----------------
------------------IVRGEGAQTFQLISENKTYYLTAESPSLLEEWIRVLQSLLKV
QVTGPPALHQGGAKPTVKGWLTKVKHGHSKLVWCALVGKIFYYYRSHEDKRPLGCLPVQG
AHIEEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIRTKHEKDTWLYHLT
VAAGGS--STRVGTLYEQLIGKLMDGE-GDPDSPIWRHPMLCYSRDGLCASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVRQQLQRHADPR--SETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1465)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKPSQSGFALFTDDPSGRDLEHCLQGRVKICDAISKWEQTLKELHPGKSD
GGTRVVKLMYKNRLYFRSQVKGET

PF00373 // ENSGT00920000149052_1_Domain_4 (1465, 1624)

ERERLLLAFQTSGEIVAGRFPVTKELALEMAALMA-
QVEYGDLEKPILPSPGGTPPAKAQHLLQQVLDRFYPRRYRNGAPPEQL------------
-----------------------RHLADTMATKWAALQGCSPSECIRIYLTVARKWPLFG
AKLFAAQPDQP-SSKEKTLVWIAVNEDGVSILDHHTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDQGSGKSHIDKLIFRMPAPKITETTFMMASYMNHCSATV-NLPT--------
--KLPAARQPRDLDGK-FFPSVSCTKGPALL-

------------------------------------------------------------
----------------------------------MAELKVEVPVSVDWQKRCLTLETQLF
RFRLQASKIRELLADK---MQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEG
SLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAELE
-MENQHLKSHNQRLVEQVGSLQDALE----------------------------------
--------------------------------------------------------AIQI
------------------------------APSWKLLVPPHGAAEQDSVPSEPGIQPMGQ
D----------SGSQA---------------QG-LKAAVLA--PSPGALQ-NKDSVSEAA
SPLEDS------SSSTVHSGETVEAKPLQPHLGRESP---------------PHQPCM-K
LLTFRCSSASWGEG-------------LVTAQ-RGMLPGTKTSAREGGPGSSLTLPKVRA
PGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSGLPELE-SR--ARSREEP
EKMEMEEPPPAGKNEERES---------PKVLGAELEEVELGNKPPTPPLHQFSSWES-R
IYAVATSGMRLSDVSPRSNTACCA--------SSPPALVSP-GSFSGLVYKNVTVPVYTA
LKGRATQISNMPFMDESSGSDDDCSSQASFQISVPSSESRKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----GLGLGGESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSQVKTWKRRWFVLRQGQILYYKSPSDVIRKPQGQVDLNSRCQ-----------------
------------------IVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSL

ENSGT00920000149052_1_Linker_0_1 (1018, 1038)

LKV
QATGPPALLRGGTKPTV

PF00169 // ENSGT00920000149052_1_Domain_1 (1038, 1140)

KGWLTKVKHGHSKVVWCALVGKTFYYYRSHEDKRPLGCLPVRD
ARIEEVDRSCDSDEDYEA-GGTRRLLSSHCTLVIHPTEHSPTYLLIGTKHEKDTWLYHL

ENSGT00920000149052_1_Linker_1_3 (1140, 1231)

T
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYASLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPR--SETGQYATYCQR
AVERTLRTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFTNGTYQVVGFDGSSTVDEF
LQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSREIVAGRFPVNKELALEMAALMA-
QVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFYPRRYRHGAPTEQL------------
-----------------------RHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQLSSKE-NALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFM-
-LVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCTTTV-NPPT--------
--NPPGACQLWELDGRQFFSSVSCATKGPTLL

MEFRELWSEAKVLD---GERQVPCI----DVPR-HCLVTEQFFSHIGLSVGGAHTQTGSG
WCS---------CPFGFLEHCRRCPRWTN--NFTMAELTEENGSCTDWQKRCLALESQLF
KFRLQASKIRELLAE---KMQELEQRVIEAEQRAEDAEKQVRVMGEEIKLANMKTSESNS
TLYRKYQELMGTVQRKEDMISRLETQLAKQKQLRTEEAKIIQEKAAKIKEWVTFKLKELE
-LENYHLKNCNQRLTEQIEALQDTLQDMTSIPP---------------------------
------------------------------------------------------------
----LESLWSCN-------------S----MKPRVPQTSYHEKTDQKSRLLAPAFRQVCQ
TGSTKRLLSTTNIVLASGNFTEDGEDRSLLSQNTLKILTD---SPNWNLSTEKDMFPDIS
SEHRLRYSDPMSLDTPAEPTKLHGALTFQSSLEGNHSTVSTLERVTLDRASFPDDLAA-T
FHSHCLDSSFSGEIMSIFEGRLQTAEPPRVVSASAVTACSICPEREYGLGTSMTFPKIRT
PSTPRDSIQLAKRHYSQPQSGTSSSCHVMSFEASNFQPIKDSPVCHRPVEETDIDDDAVL
EKMETEGGVVREEAGMCEI--NHLPTEQREVSSSKTGILEPGGKPPTPPLHRFPSWES-R
IYAVAKSGMRLSEVATVNDASSCF--------PNF-SYSAS-GPFTCLIYRNTTVPVYTT
LKGKATQISNVPFLDESSGSDDDCGSHASFRNSAAGSENRKTSMPGSPRAAKR-GVS-MS
SVSSESDYAVPPDAYSLDGDYSEPEHKLQRTSSYSTD------GGICTEPI

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSQVKMWKRRWFVLRNRQIMYYKSPSDVIRKPQGQMELNSSCQ-----------------
------------------IVRGEGSQTFQLMTEKRTYFLTADSPNILEEWIHVLQSILRV
QVTSPVGVPHSDAKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRNHEDKCPLGHLPMRE
SKVEEVDRSCDSDEDYETTGG--GLLSSHCTLVIHPQDQSPTYLLIRTKQEKNTWLYHLT
VAAGSR--NATVGTSYEQLIGKLLDAE-GDPNSPLWKHPMLCYSKDGLHMSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEASSIDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLTHTELQNEIFCQLVKQTNC
RQ--PQNHSVI-QCWQLLALCAPLFLPQHHFLWYVKQHLQRHADPR--SEIGKYAIYCQR
SVDRTVQAGEREAKPSRMEIV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEF
IQRLNQETGMRKPSHMGFSLFTDDPSGRDLEHCLQGNMKICDVISKWEQALKELHPGKYE
GGTRIVKLTYKNRLYFRSQAKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLAFQVSSEIASGRFPVNKELALEMVALMA-
QVEYGDLDRTASSSPGGTSHSKMQHLLHQVLDKFYPKRYKKNIAPEQL------------
-----------------------KQLADRLATKWMVLQGCSPPECIRIYLTVARKWPLFG
TKLFAAKPVLPSSLE-DCPVWIAVNEDGISILDYNTMHLKFSYSYSSVLTFGGCRDDFM-
-IVVSQIKERSSGKNSTEKLLFTMAIPKIVEATLLIATYINSRSTTSLLPSTQPSR----
--STAPANRLWETESRCFFASMPRSTKGPTLL

------------------------------------------------------------
----------------------------------MAELKVETRASVDWQKRCLALETQLF
RFRLQASKIRELLADK---MQDLEQRLLEAEQRAENAETQVGVMEEKVKLSSLQTVDSVG
SLHRKYQALLKAVQGKDELISQLEAQLEEQKQMRAEEAKIVQEKATKIKEWVTLKLAELE
-MENQQLKSCNERLVEQVGALQDALE----------------------------------
--------------------------------------------------------ALQM
------------------------------APSGKLLVTPQGAPEQDSVSSGPGPQTTRR
D----------SGPQA---------------QG-LKMAVPA--PSPGALR-SKDSVSEAG
SPLEES------SSSVIHSGETAEAKTLQPHLEREGS---------------PQQLCV-K
PHIPRCGSASWSEG-------------LVAAQ-GGMPPGTKTYAREGVPGSSLTLPKARA
PGTPRDSIQVAKRHHSQPQVGPGHFDHVVSIEIGAFSALHPSGLRALE-AP--AEFREEP
EQMEMEELPPARRKEEREG---------LKAPGAELEEVELGKKPPTPPLHRFPSWES-R
IYAVATSGMQLSDVSPKSITACCA--------SSPPALASP-GPFSGLIYKNVTVPVYTA
LKGRATQISNVPLVDESSGSDDDCSSQASFRASVPCSEARKTSGLGSPRAIKRG-VS-MS
SLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD-----G-----ESL

PF00169 // ENSGT00920000149052_1_Domain_0 (892, 1018)

EKSGYLLKM
GSRVKTWKRRWFVLRQGQIMYYKSPSDVIQKPQGQVDLNSRCQ-----------------
------------------IVRGEGAQTFQLISEKKTYYLTADSPSLLEEWVRVLQSLLKV
QTTGPPALPRGGTKPTVKGWLTKVKHGHSKLVWCALVGKTFYYYRSHEDKRPLGRLPVRD
ARIAEVDRSCDSDEDYEA-GGTGRLLSSHCTLVIHPPEHSPTYLLIGTKHEKDTWLYHLT
VAAGGS--SAKVGTAYEQLIGKLMDGE-GDPDSPLWRHPMLCYSKDGLYTSLTTLPSEAL
QTEALKLFKS--CQLFINVPVEAASVDYHV

PF00784 // ENSGT00920000149052_1_Domain_3 (1231, 1342)

SLAQTALQVCLVHPELQSEIYCQLMKQTSC
RP--PQKYSLM-QCWQLLALCAPLFLPQHHVLWYVKQQLQRHADPR--NETGQYATYCQR
AVERTLQTGEREARPSRMEVV

ENSGT00920000149052_1_Linker_3_4 (1342, 1466)

SILLRNPFHHSLPFSIPVHFANGTYQVVGFDGSSTVDEF
LQRLNQETGMRKSSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQALKELHAGKSE
GGTRVVKLMYKNRLYFRSQVKGETD

PF00373 // ENSGT00920000149052_1_Domain_4 (1466, 1624)

RERLLLASQTSGEIVAGRFPVNKELALEMAALMA-
QVEYGDLEKAVLPGAGGTPPAKAQHLLQQVLDRFYPRRYRHGAPPEQL------------
-----------------------RHLADVLTTKWAALQGCSPPECIRIYLTVARKWPFFG
AKLFAAQPAQVSSKE-NTLLWIAVNEDGVSILDHNTMQVHITYPYSSVMTFGGCRDDFM-
-LVIKSIPDQSSGKGQIKKLIFRMAAPKIAEATFIMASYMNHCSANV-NPST--------
--NPPAARQLWDLDGRQFFASVSRATKGPTLL