Query Results 

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---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKRSALASPERETPEIPISQPNS-KSSG-GSRP-GSQQ
ISLENQSNSPGSSNTLGKAGEG-AGSPDPE--QMTSINGEKAQERGSSATPAKKSLPFKR
GVRRGDVLLMVAKLDPDAAKPER-THSHDTP------SCQTPSPA-------ADSGKEKK
GEISRTPCGPQAG---AEILAPKAEKTRTGGLGDPGQEMVALKKGEKG---QSLVGKA-G
GAPKTKELKEGES-QGKDSQGTRPPAQGPG-EGVQ-----------------------AG
TAEKEGGEPTNTVEKGDVSKDVGSEGK--------HVGPQIPGRKWGGFLGRRSKWDGPQ
NK-DKGEVLSSKGGKTGEPQTQ-----T---------------EKASQGQGS---SGGDL
RM-GEKAGELRSSV-----------GRAGESRD-----------------------KEEK
TGQPQGK--------------SGEAG-EAPGQIKKGCEAPDEVSKTV----EPPAAAGKG
GWPGSRGQEAEEPCSRAADGA---GALETELEGLSQPPLEKDAERP-QIPKEKQDGPAPH
EAGKGGPSRD-G--DQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADPP
AGRVRLCIDADKTITEVDEEHVHR------------------------------------
------ANPPELDWA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1523)

EDLASLISVNESSVLNTLLQRHRAQLPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----RNRRDGLP-AHIGSMAQRAYWALLNHWRDQSIVALGRSGAGKTS
CCEQVLEHLVGMAGSLDGRVS-VEKVRATFTLLRAFGSVSVAHSRSATRFAMVMSLDFNA
TGRITAAQLQTMLLEKSRGARQPEGESNFQVFSQMLAGLDLDLRTELNLHHVADSSSFGM
GVWSKPEDKQKAAAAFAQLRGAMETLGISESEQRAIWRVLAAIYHLGVAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQVTFGPSQWG---LE-HEEAT
SGLKMTGTE-CVEGMASGLYQELFAVVVSLINRSFSSHHLSTASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLER-YREEGVPVQFDLPDPSPGATVAVVD
QNPS-QVRLPA-GGGAQDARGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKEGAGT----
EGSSALRACEQPLQCEIFHQLGRDPVRYDLTGWLHRAKPNLSALDAPQLLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALI
SMIKRSRLHFIHCLIPNSVVESRNRRESPTLPQPGRDKPGAGGPLAPDIPALRVQLAGFH
ILEALRLHR---SGYADHMG----LAHFRRQFQVLDPPLLKKLLSTSEGIDERKAVEELL
ETLDLEKKAVVVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRQKLEK
SEKLRNELRQNTD-VLESKIADLTTELADERFKGDVACQVLESERAERLQTFREVQELKS
KYEQAQKNLGDVNKQLEEAQQKIQVNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYEGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQET
LQLKQEVEMLQDHKRELLGSP-SLGENGVAGLKERLWKLESSAAEQQKIQSQQESTIRQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLSTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENVTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSHYYQRRLEELKADMEELMQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SLATDTMRTASRQSATSSHI---LSPRI----SEEAGDAERTQP---
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--VS---TLNRGWSTDVRSKTSEDKPV---SPHFARRPKYSHLGDGEGL-----------
-TIQRKST---ERLEA-VSSPLASRSANTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
HG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRVVGPRSPLEIEGA
A----GGLSRSTSLKCISSDGVGS-TALLPEKPKARFSSCESLLESRPSM---GRKLGSP
TT-PRDTLLSPVLRPRRRCLESSVDDAGCPD--LGNEPLVFQNRQFAHLMEEPLSSDPFS
WKVPSLNYERKTKVDFDDFLPAIRKPQTPTSLAGA-ARGGQGGSQRSSVHFEPEE-ADRT
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDGDER
T-SPELRE-PGT----GRK-DDDVASIMKKYLQK-

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-----------------------------LNTLLQRYRAQLPHTCSGPDLIVLQSPAPSA
PSA-----GKVP----WGCQD

PF00063 // ENSGT00920000149027_1_Domain_1 (922, 1518)

GLP-AHVLGLAQRTYWALLSQRRDQSIVALGRSGAGKTT
CCQQVLEHLVGMAGSVDGSVS-VEKLQATFTILRAFGSVSTGHSRSATRFAMVMSLDFNA
TGRVTAAQLQTVLLENSHVARQPEGEGNFEIFSQMLAGLDLDLRTELNLHQTVESSAFGM
GVWSKPEDKQRAAAAFAQLRSAMETLGISEVEQQAIWRVLAAIYHLGVAGACK------V
GRKQFMRFEWANRAAEVLGCDYEELNTATFKHHLRQIIQQMTAGPKRRG---LK-DEDTG
SGLKMTGVE-CVEGMASGLYQELFAALVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCRNYAHERLQLLFYHRTFVSTLER-YKEEGVPVHFDLPESSPATTVAVVD
QNPS-QVPLPARGEGSEGAGGLFWVLDEEVRVEGSSDSVVLER-LRATFEMKTARAKG--
------KGTRQPLQCEVPHQLGQDPVRYDLMGWLHRAKPNLSALDAPQVLQQSKREELQK
LFQTRAKLPPVCRAVAGLEGTSQQALHRSRVVRRAFASSLASVKRKAPCIQIKLQMDALI
SLVRRSRLHFIHCLIPT

ENSGT00920000149027_1_Linker_1_3 (1518, 1547)

SVIGSKGGQGTPSPPQPCGDQGGADESPA

PF00063 // ENSGT00920000149027_1_Domain_3 (1547, 1637)

LDIPALRVQLAGSH
ILEALRLHR---TGYAEHMG----LAQFRRRFQVLDPPLLKKLKSTSEGIDERKAVEELL
QTLDLEKKAVTVGHSQVSVHLRTSRPLYRNSDDIQ------FLSHPMPYHSGSPSSRL--
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---------------------MAISSRLALWEQKE-IIREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARLKKQAALASPERETPEIPISPPHS-KSGS-ATRP-GSQQ
ISQDSQSGSPLSSHIPGRGSEE-AGSPAP----MTSINGEKTQEPGPSGTPAKKTLPFKR
GVRRGDVLLMVAKLDP-----EQRAQPHDSP------TCKSPPPA-------TDPGGTKK
GETTKTPCGPKAS---TEDLAPKTEKAQTESLGELGQGTV-LTKSEKG---QGTLGKG-D
GTPKNKGSKGGEP-QGKEGQVARPPAQGPA-KGGE-----------------------PG
PEEKEGGDLPDKMEKGTLPKDAGSKGK--------HTGPQILARKWGPSLAGRSKWDGPQ
KKKDKEGGPQSKAGSEE-PQTDT--------------------ERTGQVEGEQG---DGL
G-MMEKAGEPQRTSGEVGGA-----------QD-----------------------KVSK
MERPRSKP---------REV-SE--APSQTEKAEKSCKVPKDGESKE----KSPAMAGKE
GQPESRGLRGQEPHAREDGGA---GALETELEGPRQPALGGDAQRTQ--KQEKQEGPTLQ
EEAEGGQSGDSDQXXXX-XXXXXX----------XXXXXXXXXXXXXTVLKPDEGTADLP
AGRVRLCIDADKTVTEVDEDQIHRXXXXXXXXXXXXXX----------------------
--------------------XXXXXXXXXXXXXXXXXXXXXPHTST

PF00063 // ENSGT00920000149027_1_Domain_1 (887, 1640)

GPDLIVLQPPGPLA
PSA-----GKVP----RGRRDGLP-AHISSLAQWAYWALLSQRRDQGIVALGRSGAGKTS
CCQQVLEHLVGMAGSVDGTVS-VEKIRAVFTVLRAFGSVSTGHSRHASRFSMVMSLDFNA
TGRVTAAQLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTELNLHQMADSSTFGM
GVWPKPEDKQKAAAAFAQLQGAMETLGISESERRAIWRVLAAIYHLGAAGACK------X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X---XX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLSSHHLSMASIMVVDTPGFQNPRHQG
KERAATFEELCHNYVHERLQLLFYQRTFVSTLER-YREEGVPVHFDLPESSPATTVAVMD
QIPSQXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXX-XXXXXXXXXXXXXXXX
XXISALRTCEQPLQCEISHQLGHDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
TSVIRSQLHFIHCLVPNPVVESRSGQGSPTPPQPGGDVPGAGGPPAVDIPALRVQLAGSH
VLEALRLHR---TGYADHMG----LTQFRRRFQVLDPPLLKKLTSASEGLDERKAVEELL
QTLDLEKKAVAVGHSQVFL

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KAGVVSRLEKQREKLV

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

SQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNMAVFLEVKDWPWWQLLGSLRPLLSATVGNEQ-LRAKEEVLTTLKRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQALESERAERLQAFREVQELKX
XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXDEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELSSRKELEQKLGELQSAYEGAKKTVHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKDMQL---SALGESVFEK-LREKATQE-NSVRWELGQ---LQQQLKQKEQEA
LQLKQKVEMLQDHKRKLLGSP-SLGEICIAGLKERLWKLESTALEQQEIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTADLESMHSELENMTKSKSLXXXXXXXXXXXXXXX
X--XXXXXXXXXXXXXXXXXXXXXXXSAADIGQIQELQLQLEEVKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAIICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SRAATSESQQRENSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGG---SGRKEXXXXXXXXXXXX
XXXXXXXXXXX--XX--XXXXXXXXXXXXXXXX---XXXXX--XMNKEAGDAERIQP---
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--A---SALSRA--QDVRSKTSGDKSV---SPLSVHRRKYCHLGDGEGF-----------
-GVQKKPT---ERLGV-LSSSPASRSRDTSPLS-RDKLPSPSAALSEFVEGLRRKRSQRG
RG-------STLSLEDWPTLPIYQTTGASTLRR-GRASSDEGHLSLRLG-AKSPPETEGA
TGGTSAGLLRSTSMKCISSDGIEG-ATPLPETLKTRFSSCESLLESGPGL---RRKLSSP
TA-PRDTVLSPTLRPRRRCLESSVDDAGCLD--LGKEPLVFQNRQYAHLMEEPLDSDPFT
WKLPSLNYERKTKVDFDDFLPAIRKPEMPMSLAGA-AKSGQDSSQRSSVHFETEE-ADRS
FLSGIKTILKKSSESKEDPAHLS---DSSSSSSSILSFKSADSIKSRPRIPRLDGDGGER
T-SPEIRE-PGA----GRK-DDDVESIMKKYLQK-

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---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALASPERETPEISVSQPNS-KSSS-GTRS-GSQQ
ISQDNQSSSLGSSDILGKESEG-SGSPDHE--QMTSINGEKAQELGSSATPAKKTLPFKR
GMRRGDVLLMVAKLDPDSAKPER-THPHDTP------PCKTPPPA-------TDTGKEKK
GETSRTPCGPQAS---TEILAPKAEKTRTGGLGDPGQGTVALKKDEKG---QSIVGKG-G
GTPKTTELKEAEP-QGKDRRGTRPQAQGP--EGVR-----------------------LG
KAEKEGAEPINTVEKGNVSKDVGSEGK--------HVGPQIPGRKWGGFLGRRSKWDSPQ
NKKDKEGVLLSKAEKTGEPQTR-----T---------------EKTSQVQGE---LGDDV
TM-GEKAGELWSTT-----------GKAGESWD-----------------------KKEK
MGKPQGK--------------SGKAC-EAQSQTEKGCEAPKEVSTMV----ESPAAPGKG
GWPGSCGQEAEEPCSRAGDGA---GALETELEGPSQPALEKDAERP-RIQKENQDGPAPQ
EEGKGGQSRD-S--DQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKTITEVDEEHVHR------------------------------------
------GNPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1657)

VEDLASLISVNESSVLNTLLQRYRAQLPHTCVGPDLIVLQPRGPLM
PSA-----GKVP----KGRRDGLP-AHIGSIAQRAYWALLNQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTVLRAFGSVSVAHSRSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQLEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GMWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAVWRVLAAIYHLGAAGACK------A
V-----------------------------------------------------------
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--------------------------------------------------------EELL
ETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAARCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIHLNDLERNPT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQQVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEA-KTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SLATDTTRTPSRQSATSSRI---LSPRI----NEEAGDTERTQS---
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--AL---ALSRARSTDVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKST---ERLEA-AASPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGAGG-TTLLPEKAKTRFSSCESLLESRSSM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDVGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLARA-AKGGQDRSQRSSIHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDGGEQ
M-SPEHRE-PET----GRK-DDDVASIMKKYLQK-

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---------------------MAISSRLALWEQK-----EKDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALASPERETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-VGSPDPE--RMTSINGEKTQELGSSATPAKKTLPFKR
GMRRGDVLLMVAKLDPDSAKPER-THPHDTP------PCKTPPPA-------TDTGKEKK
GETSGAPCGPQAS---TEILAPKAEKTRTGGLGDTGQGTVALKKGEKG---QSIVGKG-G
GTPKTKELKEAEP-QGKDRQGTRPQAQGPG-EGVR-----------------------PG
KAEKEGGEPTSPVEKENISKNVGSEGK--------HVGPQIPGRKWGSFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----T---------------EKKNQMQGE---LGDDL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAERPCSREDVGS---GALETELEGPSQPALEKDAERP-RIQKENQDGLAPQ
EAGKGGQSRN-S--EQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1435)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSVVALGRSGAGKTA
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQIFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGISESERRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPEPSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKSWEF--
---FRRAKCSVCRAVAGLEDSRG-------------------LRKHGEG-----DFARLA
GMIKRSRLHL-SLLVLNPVVESRSEQESPTPPQPGRDKPGAGCSLWV------------P
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLNLELTARKELEQKLGELRSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQEVEMLQDHKRELLGSP-SLGENCVASLKERLWKLESSAVEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGTVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGKKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTVRTPSRQSATSSRI---FSPRI----NEEAGDAERTQS---
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--A-----LSRAWSADVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKST---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRI-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-MTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDVGCPD--LGKEPLVFQNRQFAHLIEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSQRSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRHVGDGGEG
T-SPEHRE-PGA----GRK-DDDVASIMKKYLQK-

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------------------MG----FPQFRRQFQVLAPLFVKNLPSASEGIDEGKAVRELL
EALDLEKRSVRVGRSQVFLKAGVRARLEKEREKLVSQSVVP

PF00612 // ENSGT00920000149027_1_Domain_4 (1662, 1676)

FQAACKGFLSRQKF

ENSGT00920000149027_1_Linker_4_6 (1676, 1777)

KRAKM
ERLAALCIQKNLRAYEAIEDWPWWRLLAAVRPLLSTALEAHQ-LRAKEEELEALRRKLDK
SEKARNELRQNAD-QLGSKIADLTMELSDERSKGDV

PF11570 // ENSGT00920000149027_1_Domain_6 (1777, 1900)

ASRVLEGARAEGLRASREIRELKS
KYEQVQKNLGMVEKQLEEAQKKIELCESEKSNS-IGDDGWQTRFDCAQMEIEFLRKRVLQ
CEERLESELNSRRELDQKLGEAQSALEGAKKAAQQLKRKCRHLTCDLEDARVLLESQQSR
NHELEKRQKRFDMQLAQALGESRFEKSLREKVTQENTSIRWEFSK---LQQKFEVRAGIP
IRFGVFFNG---------------------------------------------------
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---------------------MAISSRLALWEQKE-SIREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQKKQAALASPEPETPELSTSQTNS-KSSS-GTSS-GSQW
ISQDTQSSSSGSSNIPGKDGEG-VGSTSPV--AMTTVSEEKALEPGSGGTPAKKTLPFKR
GVRRGDVLLMVAKLDPDSAKPEQRTPP----------PCKTAPPA-------TDPGGGKK
GETPGTPCGPQAG---TEHLAPKAEKTRTGGLGGADQGTVLLTRGRKG---QGTMGRG-D
GAPQTKGPTGAEP-QGKDGQGTRPGAQRPR-EGAQ-----------------------SG
TAEKEGGDLPSTVEKGTLSKGAGSEGK--------HAVPQIQARKWGGFLGRRSRWDGPQ
NQRSKEGELPSGAGEKGEWQSE--------------------------------------
-----------AGE-----------GKAGEQEG-----------------------EKGE
AAQPQSR--------------PGEAG-GARSPTEKGSKAPTEKGG-------------KA
PGGERPARGAQEPCAAG-AGD-AAGARQGAPEGPGQPAAERDAEGPGT-GAETPVGPDPQ
EEGAGGRSGD-A--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTANLP
PGRVRLCVDADKTVTEVDEEYVHR------------------------------------
------ANPPELDH

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1517)

VEDLASLISVNESSVLNTLLQRYRAERLHTRTGPDLIVLQSPGASA
PPA-----GKVP----TGRRDGLS-AHIGSLAQRAYRALLSRQTDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSAEGRVS-VEKIRATFTVLRAFGSVSTGHSRHATRFAMVMSLDFSA
TGRVTAAQLQTMLLEKSRVAQRPEGEGNFQVFSQMLAGLDPDLRTELYLHQMADSSSFGM
GVWPKPEDKQKAAAAFAQLRGAMELLAISESEQRAIWRVLAAIYHLGAAGACR------V
GRKQFMRFEWANRAAEALGCEYEELNTSTFKHHLRQIIQQVTLGSSRRG---LE-EEETS
SGLKMTGVE-CVEGMAAGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHRG
KDRAATFEELCHNYVHERLQLLFYQRTFVSALER-HRAEGVPVQFDLPEPSPGATVAVVD
QNAS-QVRMPA-GEGAGDAQGLFWVLDEEVRVEGSSDNTVLER-LCAAFEKKGAGA----
EGTSALRSCEQPLQFEISHQLGQDPVRYDLTGWLRRAKPNLSTLEAPHILQQSKREELRR
LFQARAELPPVCRAVAGLGGSSPQALQRSRGVRRTLAGSLAAARRKATCSQIKLQMDALT
GMIRRSRLHFIHCLVPHPAVESRGGQGSSTPPEPGGDKPGAGGPLAPDIPALRVQLTGSH
ILEALRLHR---AGYADHMG----LTQFRRRFQALDPPLLKKLTMTSEGIDERKAVEELL
QTLGLERKAVAVGYSQVFLKAGVVSKLEKQQEKLVSHSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGHEQ-LRAKEEELMTLRQKLEK
SEKSRNELRQNAD-LLESKIADLTTELADERFKGDVACRVLEGERAERLQAFREVQELKS
KYEQVQKNLGEVEKQLEEAQQKIQLHASERTRP-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDAELACRKELEQKFSELQSAYEGAKKTAHQLKRKSHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSIRWELGQ---LQQQLKQKEEET
SQLKQEVKMLQDQKQELLKCP-SLGENCIAGLKEKLWKLEAGALEQQKIQNQQENAIKQL
QQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLQQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLADVQLLLSTMEDSKTSIS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRSKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNDLMQKHKELIAQSATDIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQTRIEHLEQSTVDRAIVSRQEAVICDLENRTEFQKVQIKRFEVLVLRLRDSLIKMGEEL
SQAAASESQQRESSRYYQRRLEELKADMAELARREEEASRRCMELEKY-VEELATVRQTL
QTDLEASIRRIADLQAALEEVVSS-DSDVESVQTAVDFGG---GGRKDMDNVSILSSQPE
GSLQSWLSCTL--SLATDTVRTPSRQSASSSHI---LSPR----ANEEAGDPEPPQA---
------------------------------------------------------------
--AS---ALSRA--RDVRSKTAGDKAV---SPRSLHGQKHCRFGDNEGS-----------
-GVLGKPAAAAERLEA-LSSPLASRGADTSPPP-GEKLPSPSAALSEFVEGLRRRRAQRG
PG-------AALGLEDWPTLPIYQTTGASTLRR-GRASSHEGDLSLRSG-AKSPLDSEGA
AG-TSAGLLRSTSLKCISSDGPGATTSLLPEKPKTRFSSCESLLESTPNL---GRKLSSP
TA-PRDLLLSPTPRPRRRCLESPADDAGCPD--LGKEPLVFQNRQFAHLMEEPRGSGPLR
WKLPALDCGLEAEAGFDDFLPAIRKPDTPASLARA-AKDGQDGSKRSSVHFETEE-ADRS
YLLGVRTVLRKSPEPREDPAHLS---DSSSSSSSIVSFKSADSIKSRPGVPRPAGGGGGR
G-SPEHRE-PGA----RRK-EDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRRKQAVLASPERETPEVPASQPKR-KSGS-DNKP-GGPQ
LTQDGQPKSPQSTDIPATESQG-AGSLDPA--LRTSINGEKLQEPGPGGAPTKKTLPVRR
GVRRGDVLLMVAKLDPDAAKQAQ---P-----------QDALPIA-------TDPGGGAK
GEIPQT------S---PVALAPRTDKTQAGVSGDSGQ----GSKSERG---PGLRGKG-V
GAPQAKG---GEP-YGTEGPGTKPQTQESSERGRL-----------------------VT
AQKEGGGDPPSQTAKGTLSKGAGGKEK--------LTGPPVQARKWGGSLGRRTRGDSVQ
GKKDRAGEAEKVSQAQ-------------------------------------GQAGEVP
RVMENE--------GQAGGP-----------RE-------ELGKGS-----CAPS-----
-------------------Q-AGEAAAAQSEAVEEGQKVSKDG----VSRGESPGAARRE
GQ--RQGQAAEEACPGVEEGAETRPAEQSQAGEPATPG-------P-QVQTQSQQGPVLE
EVDTGGQSGGTS--GQIPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEETMNPP
AGRVRLRTDANYTTEEIAEEQVHA------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

VEDLASLVSINESSVLHTLLQRHRARLPHTCSGPDLIVLQPRGPAA
PSA-----GKVPM--SRGRWGHSQ-AHVASLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLQHLLELAGSVDGRVS-VEKIEATFTVLRAFGCVATGQSRGATRFAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVVRQPEGEGNFEVFSQMLAGLDLDLXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------X
XRKQFMRFE-ANHAAEALGCEYEELNTATFKHHL-QIIEQVTSGPSRRG---LQ-EEETS
SGLKMTGTE-CVEGMASGLYQELFAAVVSLINRSFSSQHLSMASIMVVDCPGFQSPRHQG
KERAATFEELCHNYAHERLQLLFHQRTFITL--R-HREEGVPVQFDLPESSPATSVAVVD
QSPSQQVHLAA-GGGTENAKGLFWVLDEEVRLEGSSDSVVLER-LCAAFEKKEAEV----
EGTSALRPCEQPLHCEIFHQLGQDPVRYDLTGWLHRAKPNLAALDAPQLLQQSKREELRS
LFQARAKLPPVCQAMAGLEGTSQQALRRSRVLRRTFASSFASVKRKAPCFQIKLQMDALI
GVIRTSHLHFIHCLVPTPLLESRGGQGLPTPSQPGGDKPGVGGPVTLDIPALRVQLAGSH
ILEALRLHR---AGYADHMG----LTQFRRRFQALDPPLLKKILLAPEGVDERKVVEELL
QSLDLEKKAVALGHSQVFL

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KAGVISRLERQREKLV

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

SPSIVLFQAACKGFLSRQEFKKLKI
HRLAARCIQKNMAVFLAVKDWPWRQLLGSLRALLSATLGHEQ-LRAKEEELRALRQKLEK
SEKLRNEFRQSTD-LLESKVADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KCEQVQKKLGEVEKQLEEAQQKIQLNDLERKHA-GGADEWQMRLDCAQTENEFLRKRLQQ
CEERLDSELTARKELEQKHGGMCIWEDGVKVMTHQQSRTIHSLTCDLEDTRVLLENQQSR
NHELEKKQKKFDMQLAQALGEFAFEKSLREKVTQENTSVRWELGQ---LQQQLQKKAQEA
SQLKQEVEKLQDQKRELLGSP-SLRENCVAGLKEKLWKLESNALEQQKIQSQQESTIKQL
EQXXXXXXXXXXXX-XXXHQDREDKEEELEDVRQSCQKRLRQLEMQLEQEYEEKQIALHE
KQDLEGLXXXXXXXIGHRDFDVKKRLPRDLKRTHALLSDVQLLLGTMEESKTSVS--KEE
LDKVHSQLEQSEAKCEDALKTQKSLTTDLENMHSELENMTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQEDLNELMQKHKDLIAQSASDIGQIQELQQQLEEAKKEKHTLQG---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVVRLRDSLIKMGEEL
SQAVAAEAQQRESNQYYQRRLEELKVDMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGP---GSRKEMDSISIISSQPE
GSLQSWSSCTL--SFAADSARSPSRQSTVSSHI---HSPRR--TV--ERGDASAM-----
------------------------------------------------------------
-------A----LARALESKTPGER--GTVSPRSIPQQKSCHSRDSEGL-----------
-GFQRKPA--AERSGA-LFASPSHRSPDTSPPP-REKLPSPSAALSEFVEGLRRKRAQKG
PG-------TSLGLEDWPTLPIYQTTGASTLRRSSRAGSDEGDLSLRVG-ARSSLGNQR-
---PAAGLLRSTSIKCISDDTQC--ARALPAEAETRLNSCESL-ESGPAL---SDQLAAQ
IL----VDLLSLTLPRSGCLESRDEC----E--LREEAASIRQAHMTILS----DSDLC-
----SCPLTQRKKVDFDDFLPAIRKPGTPTASFRA-VREGAGSPRSPSVHFEMED-ADRS
FVSGIKTILKKSPEFKEDPGHLS---DSSSSSSSIVSYKSADSIKSRPGLPRLQGDGGEA
RASPENRG-EQAPVRRDNNNDNDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK-----EKDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALASLEQETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-VGSPDPE--RMTSINGEKAQELGSSATPAKKTLPFKR
GMRRGDVLLMVAKLDPDSAKPER-THPHDTP------PCKTPPPA-------TDTGKEKK
GETSGAPCGPQAS---TEILAPKTEKTRTGGLGDAGQGTVALKKGEKG---QSIVGKG-G
GTPKTKELKEAEP-QGKDRQGTRPQAQGPG-EGVR-----------------------PG
KAEKEGGEPTSPVEKENISKNVGSEGK--------HVGPQIPGRKWGSFLGRRSKWDGPQ
NKKDKEGVLLSKAEKAGEPQTQ-----T---------------EKKNQMQGE---LGDDL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAERPCSREDVGS---GALETELEGPSQPALEKDAERP-RIQKENQDGLAPQ
EAGKGGQSRN-S--EQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSVVALGRSGAGKTA
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQVRPLGGRA--RGP------GVNSPLTPGSFCASRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPEPSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRNRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVLNPVVESRSEQESPTPTQPGRDKPGAGAPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGTDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIILFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQEVEMLQDHKRELLGSP-SLGENCVASLKERLWKLESSAVEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDKEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGTVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGKKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTMRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----PSRAWSTDVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKAT---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSQHSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---ESEEDKSPPPSSPPPLFSIIPGG
FIKQLVR----ETEKESKEARRRKEAALASPEAETPEVPTNQANK--TNN-VPKS-GSQQ
TSQDSSSATQKDADIPGKEPPG-ADDKSST--PVTSISGERPQESSPAGTPAKRTLPLKR
GVRRGDVLLMVAKLDPELAKPEQKTQPRDTP------KDKTPAPT-------TDPGGTKK
GATTGAPCGPQAP---V------PEKNVTGDDGATGQ----GTKEGKS---QGLEGKE-S
RDPQTKGQKERES-QSMEGQGTPSPVQGVG-KKGQ-----------------------VG
TVEKERGGPPKKMEKGDGSKGAGAEVR--------SLEPPVPTRKWGGSLGRRSKWDSSQ
SKNR-ESESQRRGEKMGKA-----------------------------------------
---------------------------------------EGRGQPQ-----EAPGN-MEK
AERPQKKP---VTPEKCREQ-PEVAV--ETQSPQESCKAPGGIPTEE----TPAEAARRE
NQPESRVQVAKEPCVHAEEEV---DIVESQAEGHVDSIPKPHSERP-SMQKPVEEKQVLQ
DSGSGGQSGD-SDQA-S-GDSWYEAQ---KVW--LVQKEGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTVTEVDEEQVHR------------------------------------
------ANPSELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLVSVNESSVLNTLLQRYRAQLPHTHSGPDLIAMQPQMTTV
LPA-----GKVP----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKLQAAFTVLRAFGSVSTGHSRRATRFAMVMSLDFSA
TGRITAAQLQTMLLESRHVAWQPQGEGNFEVFSQLLAGLDMDLRTELNLHQMAESSAFGM
GVWPQPEDKQKAGAAFSQLQGAMELLGISEDEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWASRAAEALGCDYEELNSATFKHHLRQILEQMTSGPQRQG---LE-DNEAC
SGLKMTGAE-CVEGMASGLYEELFVAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCYNYAQERLQLLFYHRTFASTLER-YREEGISVHFDLPEPSPGTTVAVVD
HNPS-QVHLPA-GRSSEDARGLFWVLDEEVRVEGSSDSVVIER-LRTAFEKNK---EA--
GRPPVLRTCEQPLQCELFHQLGLDPVRYDFTGWLRRAKPNLSAMEAPQVLQRSKRKELQN
LFQARAKLPPVCSSVAGLEGTSQQALHRSRVVRRAFASGVAALKRKAPCAQIKLQMDALI
SLLSRSQLHFIHCLVPTSV-EIKTGQGTPSPPQPGGDQGGANKPPALDIPALRVQLAGCH
ILEALRLHR---AGYAEHMG----LAQFRRRFQVLDPLLLKKLDSTSEGLDERKVLEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVARNILLFQATCRGFLSRQEYKKLKI
RRLAAQCIQKNLAVFLEVKDWPWWGLLASLRPLLSPTLSMEQ-LHAKEEGLTMLRQKLQK
SEKSRSELRQSTE-LLESKITDLTSELADERFKGDMACQALESEQAQRLQALREVQELKA
KYQQVQEALGEVQKQLEEAQQKSQPVNFEEKHA-GGAEEWQMRLDCAQMENDFLRKRLQQ
CEERLDSEMKARAEVEQKLGDLQRAYEEAKKTAHQLKRKCHHLTWELEDTRVLLENQQSR
NHELEKRQKKFDLQLAQALGESMLEKTLREKVSQENSGVRWELGQ---LQQQLEQKEKEA
SKLKQEVERLQDQKRELLNCA-SVGEQGVASLKERVWELESSALEQEKVHSQQENTIKQL
EQLRQRFELEIERMKQVHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQVALHE
KRDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKVLTADLENMHSELENVTRSKTLVDEQLYRLQFERADL
L--KRIDEDQDDLNGLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQLRIQYLEQSTVDRSIVSRQEAVICDLENKTEFQKVQLKRFEVLVIRLRNSLIKMGEEL
SQAAKSEAQQRENSQYYQRRLEELKAEMQELVQREEEASRRCMELEKY-VEELAAVRQTL
QADLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---RSRKEEDNVSVISSQPE
GSLQSWMSCSL--SLATDAGRTPSRQSAVSSSP---LSPRI----SEEAGDAERLRP---
------------------------------------------------------------
--LSS--ALSGAWDTSRETSRGGSVSL-----HPVFPPKPYHLGDGEGF-----------
-AVHRKAT--PERPGT-LPSSPTSQSMAMSPPP-RDKLPSPSAALSEFVEELRRKRAQRG
QH-------SSLHLGEGPTLPIFQTTGASSLRR-GRANSDEGDLSVWTR-GKSPLGAEGI
PKA-TAGLSRSTSLKCISSEDTED-ISLLPYKQKTRVGSCESLLESGPST---RRK----
-----DPLSSPTLRPRRRCLESSVDDAVGLD--LGKESLVFQNRQFSHLLEETLDSDPFS
WKLPSLNYRRQTKVDFEDFLPAIRKPGTALSEA---AKDGKEASKHPNIHFETEE-ADRS
FLSGIKTILKKNPESKEDPAHLS---DSSSSSSSIISFKSSDSIKSGPRVPRLQGDGGER
M-SPEHRE-PGA----LRKG-DDVESIMRKYLQP-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLTLASLERETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-VGSPDPE--RMTSINGEKAQELGSSATPAKKTLPFKR
GMRRGDVLLMVAKLDPDSAKPER-THPHDTP------PCKTPPPA-------TDTGKEKK
GETSGAPCGPQAS---TEILAPKAEKTRTGGLGDAGQGTVALKKGEKG---QSIVGKG-G
GTPKTKELKEAEP-QGKDRQGTRPQAQGPG-EGVR-----------------------PG
KAEKEGGEPTSPVEKENISKNVGSEGK--------HVGPQIPGRKWGSFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----T---------------EKKNQMQGE---LGDDL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAERPCSREDVGS---GALETELEGPSQPALEKDAERP-RIQKENQDGLAPQ
EAGKGGQSRN-S--EQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSVVALGRSGAGKTA
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPEPSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRNRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVLNPVVESRSEQESPTPPQPGRDKPGAGAPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIILFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQEVEMLQDHKRELLGSP-SLGENCVASLKERLWKLESSAVEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDKEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGTVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGKKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTMRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----PSRAWSTDVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKAT---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSQRSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARLRKEAVLASPERETSDVSISQPNS-KAHS-GTKS-GSQQ
TSGDSQSTSPQSTSIPGKDSQG-SGSADPA--LTTSINGERPQEPAPRGTPARKALPFKK
GVRRGDVLLMVAKLDPEAAKPEQRTQARDVP------TCKTSPTV-------TDPGGSKK
GETPGTPSGLQAS---TEDLASKPEKTPTGGHGDPGQ----GKKGEKG---QGTVAKG-S
GGPMTKGSKGGET-KGKEEQRTRPQSHGAG-DEGQ-----------------------LG
TVEKEGGDPPSKMEKINVSKDMVSKDVG---AEGKRAGPQVQWRKWGGSLSRKSKWDGPQ
SKKDRESEPPSTTGKTGKPQAKM--------------------EEKGKGQGKAGQVGEVP
RTLEEAVELGKASE--------------------------------------A--LKSEE
VQQPKGKA---A----------G-T-GGAGTQAEKGCKTPKEVAAER----VSPVATEPE
RQPESSAQRAEEHCTKAEETA---GAPEPRQEGCGEPSRETQAEKP-PGQMQTQEGPALQ
DRGRGDHR---GDLDQDHEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTVTEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

DDLASLISVNESSVLNTLLQRARAQLLHTCAGPDLLVLQPQGPAK
LSS-----GKVS----KGRRDGLP-AHISSLAQRAYWAMLSQRRDQSIIALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTILRAFGSACTGHSCSATRLAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARLPEGEGTFPVFSQMLAGLDLDLRTELYLYHMADSSSFGM
GVWSKPEDKQKAATAFAQLQGAMETLGITEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPSRRD---LK-DEEPS
SGFKMTGTE-CVEGMASGLYQELFAAVVSLINRSFSSHHLAMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYVHERLQLLFYQRTFVSVLER-YQEEGIPVHCDLPESSPGTTVAVVD
QNPS-QVHLSA-GGGTEDAKGLFWVLDEEVRIEGSQDSVVLER-LRAAFEKTGAGAK---
-GISALRTCEQPLQCEIFHQLGQDPVRYDLTGWLHKAKPNLSALDAPQVLQQSKREELRS
LFQSRAKLPPVCQAVAGLEGTSQQALHRNRVVKRTFASGLASARRRAPCSQIKLQMDALI
SLVRRSQLHFIHCLVPTPAVDNKGGQGALPPPFA-GDQLGAGKPLAADIPALRVQLAGSH
ILEALRLHR---IGYADHMG----LTQFRRRFQVLDPVLLKKLGSAPEDTDERKAVEELL
QTLDLEKKVVAMGHSQVFLKAGVVSRLEKQREKLVSQNIILFQAVCKGFLSRQEFKKLKI
RRLATQCIQKNVAAFLAVKDWPWWQLFTSLQPLLSATVGNEQ-LRAKEEELTMLRRKLEK
SEKSRNELRQSAD-LLESKIADLTTELADERFKGDVTCQVLENEHAERLKASREIQELRS
KYEQVQKNLGEVERKLEEAQQKIQLNDLERKHT-GAADEWQMRLDCAQMENEFLRKRLQQ
CEERLDSELTSRKELEQKLGELQNAYEEAKKIAHQLKRKCHHLTWDLEDTRVLLENQQSR
NHELQKKQKKFDMQLAQALGESVFERSLREKMSQESNSVQWELGR---VQEQLEQKEQET
LRLQQEVEMLQKHKRELLESP-SLGESGMADLKERLWKLESSAREHEKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KRDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTLDLESMHSELENMTRNKTLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSATDIGQIQELQVQLEEAKKEKQKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRLEALVIRLRDSLIKMGEEL
SRAVASESQQRESSQYYQRRLEELKVDMEELAQREAEASRRCMELEKY-AEELGAVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDSESVQTAVDCSS---GGRKEMDNVSVISSQPE
SSLQSWLSCTL--SLATDTVRTPSRQSAASSCI---RSSR--------------------
------------------------------------------------------------
MNGEAGDAESRSWNV--HSKTSRDNSV---SPCSTHQQKSCHLGDGEGL-----------
-GVQRKPM---ERSRA-LSSPVASQTPDTSLPP-REKLPSPSAALSEFVEGLRKKRAQRG
QG-------PTLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGDLSLKLQ-AKSPLGVEGA
SG-TSAGLSRSTSLKCISSGGAES-MSLPPERPKTRFSSCEALLESGPSV---RKKMSSP
TT-PRSILLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPCS
WTLPSLSYGRRARVDFDDFLPAIRKSETPTPLAGV-AKHGHEGSKHSGVHFEMEE-TDRS
FLSGIKTILKKSTESKEDPAHLS---DSSSSSSSIVSFKSADSVKSRPRPPRLEGDGGEQ
M-SPEPRE-LGA----GRK-EDDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK-----EKDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKRSALASPERETPEIPSSQPNS-KSSS-GSRP-GSQQ
ISQEDQSSSPGSSNILGKASEG-AGSPDPE--RMTSINGEKAQELGSSATPAKKTPPFKR
GVRRGDVLLMVAKLDPDSAKPER-THSHDTP------SCKTPSPA-------TDPGREKK
GETSRTPCGPQAS---TEILAPKAEKTRTGGLGDPGQGTVALKNGEKG---QSIVGKG-G
GAPKTKELKEGEL-QGKDSQGTRPPAQGPG-ERVR-----------------------VG
TAEKDGGEPTNTVEKGDVSKDVGSEGK--------HVGPQIPGRKWGGFLGRRSKWDGPQ
KK-DKEEVLLSKGGKTGEPQTQ-----T---------------EKTSQVQGR---PGDDP
RK-GEKAGEPRSST-----------GRAGESRD-----------------------EKEK
MGQAQSK--------------PGKAG-EARNQIKKGCEDPNEVGTMV----EPPAAAGKG
GWPGSRGQEVEEPCSRADHGA---GALETELEGFSQPPLEKDAERP-QIPKDNQDGLAPQ
EAGKGGHSRD-A--DQVRGLRLWVGGGADG---------------------PDEGTADLP
AGRVRLCIDADKTVTEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1515)

EDLASLISVNESSVLNTLLQRHRAQLPHTCTGPDLIVLQPRGPSV
PSS-----GKVP----RSRRDGLP-AHIGSMAQRAYWALLNHWRDQSIVALGRSGAGKTS
CCEQVLEYLVGMAGSLDGRVS-VEKIRATFTILRAFGSVSVAHSRSATRFAMVMSLDFSA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHHVADSSSFGM
GAWSKPEDKQKAAAAFAQLRGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQVTFGPSRWG---LE-DEEAS
SGLKMTGME-CVEGMASGLYQELFAAIVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLER-YREEGVPVQFDLPDPSPGATVAVVD
QNPS-QVRLPA-GGGAQDARGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKAAGT----
EGSSALRACEQPLQCEIFHQLGRDPVRYDLTGWLHRAKPNFSALDAPQILQQSKREELRS
LFQARVKLPPVCRAVAGLEGTSQQALQRSRMVRRTFAGSLAAVRRKAPCSQIKLQMDALI
SMIKRSQLHFIHCLVLSPVVESGNGRESPTPPQPGRDKPGAGGPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSRSIVLFQAACKGFLSRQEFKKLKI
HRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KYEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-GGADEWQMRFDCAQMENDFLRKRVQQ
CEERLDSELTARKELEQKLGELQSAYEGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQET
LQLKQEVEMLQDHKRELLGSP-SLGENCVASLKERLWKLESSAIEQQKIQSQQESTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQMRIEHLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELMQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSATSSHI---LSPRI----NEEAGDAERTQP---
------------------------------------------------------------
--VS---TLSRGWCTDVRSKTSEDKPV---SPHFARRQKYSHLGDGEGL-----------
-TIRRKST---ERLEA-ASSPLASRSANTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
HG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRA-GTKSPLEIEGA
A----GGLLRSTSLKCIPSDGVGG-TTLLPEKAKARFSSCESLLESRPSM---GRKLGSP
TA-PRDTLLSPVLRPRRRCLESSVDDAAGPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLNYERKTKVDFDDFLPAIRKPQAPASLAGA-AKGGQGGSQRSGVHFEPEE-ADRT
FLSGIKTILKESPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDGDER
T-SPELRE-PGT----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARLRKQAALGSPEQETPETSAGQPKG-KSNS-GTKS-GNQQ
IPQGSQSGSPQNSNIPGKESQE-AGPTDPV--LMTSINGEKPQEPGPSGTPARKPLPFKR
GVRRGDVLLMVAKLDPDSAKPEQRTQPHDAP------TCKTPPPA-------TDPGGEQK
GGTPGTH-----G---TKDTAPKAEKTQTEGVVDPGT--------------QGVVGKG-G
RDPQTKGLKGGEL-QGREGPG----------EGGR-----------------------SA
TTEKGAGDPPNKMAKGNLSKDSGGNGK--------PAGAQIQVRKWGVSLGSRSKWDGPR
SKKDKEGSLLSKAEKTEEPQVK-----A---------------EKMSKVQGKPGKVGGAP
GG-VEKAGQPLRRT-----------EKAGEPQT-----------------------KVGE
ERRPQSE--------------PGEAG-RAGGEREKGCETPKEVGACR----ENPAAAGKE
GRPESRGQNAPEPRAGVDDVT---ETLETELERAGPPALEGHADSS-QDRKEGEEGPALP
EGSKGGQSRD-L--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRVCIDADKTVTEVDEECVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1517)

EDLASLVSVNESSVLNTLLHRYRAQLPHTFTGPDLIALQPRRPPA
PSA-----GKVP----RRRRDGLP-AHVGSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVAMAGSVDGRVS-VEKIRATFTILRAFGSVPTGHSCNATRFAMVMSLDFNA
TGKVTAAQLQTMLLEKSHVARQPEGEGNFEVFSQMLAGLDLDLRTELYLHQTADSSSFGM
GVWPKPEDKQKAAAAFAHLQSAMETLGISEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPGRRR---PE-GEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSCRLSMASIMVVDPPGFQNPRHQC
KDRAATFEELGRNYAHERLQLLFYQRTFVSALER-YRQEGIPVPFDLPEPSPGTTVAVVD
QNLS-QVRLPA-VGGAEDSRGLFWLLDEEFRVEGSSDSMVLER-LCAAFEKKGAEA----
EGTSALRACEQPLQFEIFHQLGQDPVRYDLTGWLHRGKPNLSALDAPSVLQQSKREDLRS
LFQARAKLPPVCRAVAGLEGTSQQALQRNCTVRKAFASSFAAVKRKAPCSQIKLQMDALT
SMIRRSQIHFIHCLVP

ENSGT00920000149027_1_Linker_1_3 (1517, 1550)

GPAGESRGGQGSLTPPQPGGDKPGTGGPLPLDI

PF00063 // ENSGT00920000149027_1_Domain_3 (1550, 1640)

PALRVQLAGSC
VLEALRLHR---AGYADHVG----LAQFRRRFQVLDPVLMKKLTSASEGIDERKAVDELL
QTLDLEKKAVVVGHSQVFLKAGVVSRLEKQREKLASHSIILFQAACKGFLSRQEFKKLKI
RRLAARCIQKNVAVFLAVKDWSWWRLLGSLRPLLSATIGDEQ-LHAKEEELTMLRQKLEK
SEKSRNELRQNAD-LLESKVAELTAELADEHFRGDVACQVLESERAERLRAFREVQELKS
KYEQVQKNLGEVQKQLGEAQQKIQLGDLERSHT-GGADEWMMRFDCAQMENNFLRKRLQQ
FEERLDSELTSRKELEQKLGELQSAYEGAKKMAHQLKRKCHHLTCDLEDTRLQLEDQQSR
SHELEKKQKKFDMQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQRLKQKEQET
SQLKQEVETLQAHKRELLGLS-SLGENCVAGLKERLWNLESSALEHEKIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQIALHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGSMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTADLESMHSELENMTRNKSLVDEQLCRLQFERADL
L--KRLDEDQDDLNDLMQKHKDLIAQSATDIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
TQAAKSESQQRESSQYYQRRLEELKADMEELVRREAEASRRCMELEKH-VEDLSAVRQTL
QTDLETSIRRIADLQAALEELASS-DSDTESVQTAVDCTS---RGGKETDNVSILSSQPE
GSLQSWLSCTL--SLATDTVRTPSRQSVISSHM---LSPRI----NEETGDAERSQP---
------------------------------------------------------------
--AS---ALSRA--RTMRSQTSGDKSV---SPLSLRRQKYYHLGDSDEC-----------
-GGQKQPT---ERLGA-RSSSPASRSPDSSPAS-REKLPSPSAALSEFVEGLRRKRAQKG
QG-------STLSLEDWPTLPIYQTTGASTLRR-SRAGSDEGDLSLGFGAQSAL-EKEGA
SG-TSAGLLRSTSLKCISSPSTEG-TTLLPKKPKTRFSSCDSLFESGQSS---GRTLSSP
ST-SRDLVLSPTLRPRRRCLESSLDEAGCPD--LGKEPLVFQNRQFAHLMGEPLDSDPFT
WKVPSLNYKRKTKVDFDDFLPAIRKPETPVSLARA-AKEGQDSPRHPRIHFETEE-ADRT
FLSGIQAILKKSPESKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPRIPRLDGDGGER
T-SPESRE-PGA----GRK-DEDVESIMKKYLQK-

------------------------------------------------------------
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-----WQREWGR------------------------------------------------
--QRESPKKAKKHHKEAPKDVWYEAD---KVW--LMQQDGFVLAT---QLKPDVGTPELP
AGRVRVRRDADGSITEVDEDSVQR------------------------------------
------TNPPHLDL

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

AEDLATLLNLNECSALNTLQHRYHSHLPYTYAGPSLVAIRPGPDAG
NHA-----GKGC----RRMLGLG----VLLGDAQEWRCSQLGTAPSQIVLLSSGSLGPTP
SMALQLLV-----------------VSPHLWVLSSA-------PCVPTPCSVCW--GMGT
ATDAHLCSLQTMLLERSRVAQQPPGESNFNIFPMMLAGLDVAQRTTLHLHQVAESNAFGI
KPFSKPEEKQKASAAFAKLQAAMGVLGITAEEQVAVWRVLAGIHHLGAAGACRDVTEAGM
GRKQFMYFEWATHAAEVLGCELEELSTAVFKHHLKQILAQAAARGGARPSE-----EEGP
SGQKMTGVE-CVEGMASGLYEELFAALVSMINRSFSSQHFSIASIAVVDTPGFHNPRHQG
GQRAATFEELCHNYVHERLQGLFYERTFVSEMER-YKEENVEVSFDLPERSPLATLSIVD
LNPS-QPQVLP-SSLGADRRGLLWILDEEVLIPGSGDGAAFDR-LCSYFAPKGSDQ----
DGAGCVRKCEQALHFEIPHQLGTDPVRYDLTGWVSKAKLNLSAENASQMLQQSQLNALQE
LAMLRRGVPRVCRAVAGLEGCSQAALQRNACVRKVFASSLAAVRRRSVCAQLKLQADALT
SLLRRSQLHFVHSLVPGTAVEKAD-------------------PLLLDVPALRAQLGGTQ
LLDALRLRR---TGYADHLL----LTHFRRRFQVLAPAVMKKCTSAYEVPDESKAIEELF
QALDLEKKSVAIGRSQVFL

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KAGVLSRLEKQRDKLI

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

AQKLILLQAACKGFLSRQKF

ENSGT00920000149027_1_Linker_4_5 (1676, 1875)

KRLKV
QRLAIRCIQKNVVVFQVVRHWPWWQLLSRVRPLLSINLAEDSQAGTDDKELVALRRKLER
SEQSCSELRQNTE-KLESKIIDLTMELSDERHKGDVACQMLDGERE-RRRGDSELQELQS
KHDQVQKKLESVQKQLEEAQQLVQLREMKISGS-EGEDAWQVRFDCAQTEIAFLQKRLAQ
LEERLSAELSSRTG

PF01576 // ENSGT00920000149027_1_Domain_5 (1875, 1936)

LEQKLGEAQAACQVARAAAQQLQRRCRRLTCELEDARVLAESQQSR
SHELEKRQKKFDLQLARHHSRGCLMKY-EHNSIQNHLPMLWEQCADPTLSPPEQQQQAEG
ASLAQRVSQLAGRVQELSAPG-ALDSCSVPVLRQQLWDLEASSAEQRKELERQTANVDHL
EQLHQRLELEIERMKQIHQKELEDKDEELEDARQSCQRRLRQLEMQLEQEHEEKQTALRE
KQDLEGLVGTLCEQIGHRDLDVEKRLRRDLRRTRALLADAQLLLAAPTEPGT-TG--TAE
LQRLQKQLEESEARCAEAQRSQQAAAQELENLHVEMEMLSRNKTLADEQLSQMQHERAEL
L--RRISEDQEDLNELMAKHKALIAQSATDIAQIQELQTQVEEVKKEKQSLQE---KLLV
AQASVARLEQRPAERAVISRQEARIRDLESQLDFQAVQMKRFEVLVLRLRDSIIKMGEEL
EKAAESEAREKESTKYYQRRMEEMKADMDELVQRELESSRRRVELEQQ-LAEAAAARQGL
QADLGTAIRRIADLQLALEELRASDDSD--------------------------------
------------------------------------------------------------
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-----------------------------------

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---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRRKEAALTSPEGETPEVPINQANK--TNN-VPKP-GSQQ
TSQDSPSATQKDADIPGKDPPR-ADDKNSM--PVTSTGGEKPQESGPTGTPAKRTLPFKR
GVRRGDVLLMVAKLDPELAKPEQKTQPRDTP------KDKTPALA-------TDPGGTKK
GATTGTPCGPQTP---I------TEKNSTGGDGDTSQ---GGTKGGKC---QGTEGKG-S
RDPQTKGQKECES-QNTEGQGTRSPAWEAV-NKGQ-----------------------VG
TVEKGGGGPPKKMEKEDGPKGAGAKVR--------PLEPPVPIKKWGVSLGRRSKWDSSQ
SKNR-ESESQRRDEKRGDLQGTA-------------------------------------
--------------------------------------AEPRGQQQ-----EAPGK-MEK
AGGSQKKL---VIPGKCQEQ-PGVT--AETQSPQECCKAPGGMPTEVTLAAEVAEAARRE
DQPESTAQGAGEPCVHAEEEV---DIEEPQAEGPVESLPKTQVERS-SLQKPMEEEPVLQ
DPG-----RD-SDQA-SEEDRWYEAQ---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCMDADKTVTEVDEDQVHR------------------------------------
------ANPSELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

TEDLASLVCVNESSVLNTLLQRYQAQLPHTRSGPDLIALQPQKTTV
PSS-----GKVP----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVSMAGSVDGRVS-VEKLQAAFTVLQAFGSVSTGHSRRASRFSMVISLDFNA
TGRVTAAQVQTVLLENSRVARQPQGEGNFEVFSQLLAGLDVDLRTELNLHQMSESNAFGM
GVWSQPEDKQKAATAFSQLQGAMELLGISEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCDYEELNTATFKHHLRQIIEQMTSGSQRQC---LE-DNDAS
SGLKMTGVE-CVEGMASGLYQELFGAVVYLINRAFSSHHLSMASIMVVDSPGFQNPRHQC
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YQEEGIPVHFDLPESSSGTTVAVVD
HNPS-KAHLPA-GGATEAAGGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKT--VGA--
DGPSVLRICEQPLQCELFHQLGRDPVRYDLTGWLRRAKPNLSALEAPQILQQSQRKELQN
LFQARAKLPPVCRAVAGLEGTSQQALHRGRVVRRAFASRVAALKRKAPCAQIKLQMDALI
SLLSRSQLHFIHCLVPTSV-ESKPGQGTPSPPQPGGDQGGANEPPALDIPAMRVQLAGSH
ILEALRLHR---AGYADHMG----LVQFRRRFQALDPQLLKKLDWTSEGLDERKVVEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSQNIVLFQAACRGFLSRQECKKLKI
RRLATQCIQKNLTVFLEVKDWPWWRLLASLRPLLSPTLSLEQ-LQAKEEELTLLREKLQK
SEKSRSELRQSTD-LLESKITDLISELADERFKGDVACQALESERAERLQAFREVQELKA
KYQQVQEALGAVQKQLEEAQQKIQLANLEEKHT-GGADEWQMRLDCAQMENDFLRKRLQQ
CEERLDSEMKARTEVEQKLGELQNAYEEAKKTAHQLKRKCHHLTWDLEDTRVLLENQQSR
NHELEKRQKKFDLQLAKALGESMFEKTLREKVSQENSGVRWELGQ---LQQQLEQKEQEA
SKLKQEVEKLQGQKQELLGCA-SVGKQGVASLKEKVWELESSALEQQKVHSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQMEMQLEQEHEEKQVALHE
KRDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKVLTTDLENMHSELETVARSKSVVDEQLYRLQFERADL
L--KRIDEDQEDLNGLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQLRIQYLEQSTVDRAIVSRQEAVICDLENKTEFQKVLMKRFEVLVIRLRNSLIKMGEEL
SQTSKSEAQQRENSQYYQRRLEELKAEMKELMQREEEASRRCMELEKY-VEELAAVRQTL
QVDLETSIRRIADLQAALEDVVSS-DSDTESVQTAVDCGS---RRRKEEDNVSVISSQPE
SSLQSWMSCSL--SLAMDTARAPSQQSVVSSSL---LSPRV----SEEAGDSEKLRP---
------------------------------------------------------------
--ESL--VLKEAWDSPRETSRSGSVSL-----LPVFPQKSYHLEDGEGF-----------
-AVHRETT--PEGPGT-LSSSPTSQSMAKSLLP-RDKLPSPSAALSEFVEELRRKRAQRG
QG-------SSLHLGEGPMLPIFQTTGASLLRR-GRASSDEGGLSLRTG-AKSPLQAEGN
PRVPTAGLSRSTSLKCISSESTEN-ITLPPDKQKTRFGSCESLLESGPST---RRKLSSP
KA-LRDPLLSPTLQPRRRCLESSVDEAVCLD--LGKEPLVFQNRQFSHLMEETLDSDPFS
WKLPSLNYRRQTKVDFDDFLPAIRKPSDPLPEA---AKDGKEATKHPNVHFEMEE-ADHS
SLSGIKTILKKNPESREDPAHLS---DSSSSSSSIISFKSTDSIKSSPRVPRLQGDGGER
V-SPEHRE-PGT----GR-S-DDVESIMRKYLQQ-

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GRKQFMKFEWANRAADVLGCELEELTTAVFKHHLKQIIAQATARGGRLPPE-----EDSP
SGPKMTGME-CVEGMAAGLYEELFAALVSLINRYGGAEPRALCTKPIVNTPGFCHPTCAF
-IGCCTLSTLCYRGATQLLFSLIRAGCLAKGLGT-GSRENVEVSFDLPEHSPLATLSIID
LNSS---QVLP-GSLGADRRGLLWILDEEVLVPGSGDSAAXXXXXXXXXAPKGPDQ----
DGPGCVRRCEQELHFEIPHQLGTDPVRYDLAGWVGKAKLNLSAENASQLLQQSRLXXXXX
XXXXRRRAPRGCRAVAGLEGCSQAALQRSACIRKTFASSLXXXXXXX-PHPLLVPQDALT
SLLRRSQLHFIHCLVPGAAADGGD-------------------PLALDMPSLRAQLGGTQ
LLVCI

PF00063 // ENSGT00920000149027_1_Domain_3 (1566, 1640)

-LCQ---KGYADRML----LTQFRRRFQVLAPAVMKKHTSAYEVPDESKAIEELF
QALDLEKKSVAIGRSQVFL

ENSGT00920000149027_1_Linker_3_4 (1640, 1656)

KAGVMPRLEKQRDKLI

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

AQKIILLQAACKGFLSRQQFKRLKV
QRLAARCIHKNLQLFQAVRHWPWWQLLSRVRPLLSVSLAEQQL-RAKEVSTMQLRAKEVR
TTQRD-RMEREGM-GQDGSSTPWXMELSDERHKGDVACQVLDGERAERLRGARELQELQN
KHDQVQKKLESVQKQLEEAQQLVQLREMKISGS-EGEDAWHVRFDCAQTEIAFLQKRLAQ
LEERLGAQRPHGARAKGKLGEAQAACKAAQVAAQQLRRRXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQQKQAEG
ASLEQRAAQLATRLQELSAPG-APDARAVPALRQQLWELEASAAEQQKELERQTAAVDHL
EQLHQRLELEIERMKQIHQKELEDKDEELEDVRQSCQRRLRQLEMQLEQEYEEKQTVLHE
KQDLEGLVGTLCEQXXXRDLDVEKRLRRDLRRTRALLADAQLLLAAPTEPGA--------
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PF00063 // ENSGT00920000149027_1_Domain_1 (1103, 1233)

MATLGILASEQKAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANQAAAVLGCDYEELSGAVFKHHLRHIIEQVTSGRGRGP---RPDQEPPT
PGPKMTGVE-CVEGIASGLYEELFGVIVSLINRYGKPTLLYKRGDFFR------------
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------------------------------------------------MQGE---LGDDL
RM-GEKAGELRSLT-----------GKAGESWD-----------------------KKEK
IGQPQGKD---K---------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVATGKG
GWSGRSGQEAERPCSREDVGS---GALETELEGPSQPALEKDAERP-RIQKENQDGPAPQ
EVGKGGQSRN-S--EQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1517)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPDPSPGTTVAAVD
HSPS-QVRLPA-GGGAQDAKGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGTGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRNRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVL

ENSGT00920000149027_1_Linker_1_3 (1517, 1551)

NPVVESRSEQESPTPPQPGRDKPGAGAPLALDIP

PF00063 // ENSGT00920000149027_1_Domain_3 (1551, 1640)

ALRVQLAGFH
ILEALRLHR---TGYADHVG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRQKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERHPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQEVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSAVEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGTVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGKKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTMRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----LSRAWSADVRSKTSGDKPV---SPHFLRRQKYCHFGDGEGL-----------
-AVQGKST---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRDILLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGRAAKGGQDGSQRSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDLAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVTSIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKESDIREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKEAKEARCRKQAELASPERETPDISTSQPSS-KSSS-GTTP-RSQQ
TPQDHQSSSPGSANIPGWENEG-ARSPEPL--QMTSVNGEKALESGSSGTPARKAPLFRR
GVRGGDVLLMVAKLDPDSAKPEQRTPPPDST------PCKTPPPP-------TDPGGEKK
GGSPVTPCNPQAS---PEDGAPKAEKTWTAGLGDPGRRTVLPTKGDKD---PSMGKKG-G
TIPHTKGPKGGEP-QGTDRQGTRPQAPELSEEGGR-----------------------RE
AVEKEGGDPSKQVEKGRVSKDAGSEGK--------SGGSQIQGRRWGGFLGRRSKWEGLQ
GKKDRASELSRKAEKREGSPAQTKAEKT---------------VKTGPAQGTVG-HGQAP
RM-VEKAGELQSRT-----------REAGEPQD-----------------------KKEE
VGQPKGK--------------SGEAS-GALSTAEKGGKTPKEVGTSG----EVPAVAGQG
VRLGSLGPMAEEPRTRADGRA---GTLEMGLEGRHQPALEKDAERP-QT--ESQEGSAPQ
EGSLGGRSGN-S--DQVTESLWHL-------F--LSRPLSFSLST---VLKPDEGTADLP
AGRVRLCIDADKTITEVDEEHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1521)

VEDLASLVSVNESSILNTLLQRYWAQLLHTCTGPNLVVLQPPGLSV
PST-----GKVP----GGRRDGLP-ALISSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLECLVGMAGSVDGRVS-VEKIRAAFTVLRAFGSVSTGHSRSATRFAMVMSLDFSA
TGRVTAAQLQTMLLEKSRVARQPEGEGNFQVFSQMLAGLDLDLRTELCLHQLADCNSFGM
GVWPKLEDKQKAAMAFAQLRGAMVTLGISESEQRAVWRVLAAIYHLGAAGACK------V
GRKQFMQFEWANHAAEALGCEYEELNMATFKHHLRQIIEQVTSGRSRRG---LK-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDPPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLER-YREEGVPVPFNLPESSPGTTVAVLD
QNPS-QVRLPA-GEGAEDARGLFWVLDEEVRVEGSSDSTVLER-LFAAFEKKGTEA----
EGNSALRICEQPLQCEISHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRI
LVQARAKLPPMCWAVAGLEGTSQQALQRNRIVRRAFTSSLAAVKRKAPCSHIKLQMDALT
SLIGRSQLHFIHCLVPNPVV

ENSGT00920000149027_1_Linker_1_3 (1521, 1548)

ESRSRQGSLSPPQPVGDKPGAGGPLAL

PF00063 // ENSGT00920000149027_1_Domain_3 (1548, 1640)

DIPALRVQLAGSH
ILEALRLHR---TGYADHVG----LTQFRRRFQVLDPPLLKKLMSASEGIDERKAVEELL
MTLDLEKKAVAVGHSQVFLKAGVVSRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
HRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELMTLRRKLEK
SEKLRTELRQNTD-LLESKIADLTTELADERFKGDMACQVLESERAERLQVFREVQELKS
KYEQVQKNLGEVEKQLEEAQQKIQLSDLERNST-GRAEEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTSRKELEQKLGELQSAYEVAKKTAHQLKRKCHYLTCDLEDTRILLENQQSR
NHELEKKQKKFDQQLAQALGECVFEKGLREKVTQENTSIRWELGQ---IQQQLKQKEQET
LKQQRELEMLQDHQRELVGSP-SLRENSVPVLKEKLWKLESHALEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVT--KEE
LEKVHSQLEQSEAKCEEALKTQKTLTADLENMHSELESITRSKSLVDEQLHRLQFEKAGL
L--KRIDEDQDDLNELIQKHKDLIAQSAADIGQIQELQLQLEETKKEKHKLQE---QLQV
AQMRIEYLEQSTADRAIVSRQEAIICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVHREAEASQRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCSL--SLATDTMRTPSQQSATSGRI---LSPRV----TEEAGDAERVPS---
------------------------------------------------------------
--AS---ALSRA--QDVHSKTSGDKSV---SLHSARQSKYCHFGDGEGL-----------
-RVQRMPI---ERLEA-TSPSLASRSTDSSSLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDCPTLPIYQTTGASTLRR-GRASSDEGDLSLRI-RANSPLEMEGA
AG-RATGLLRSASLRCISLDGVGG-TTLVSEKHKTRFSSCESLLESTPSL---GSKPRSP
PT-PRDILLSPTLRPRRRCLESSVDDTGCPD--LGKEPLVFQNRQFTHLIEEPLGSDPFR
WKLPSLNYERKTIVDFDDFLPAIRKPETPMSLAGA-AKDGQDGSKHPSVHFEMEE-SDRS
FLSGIKTILKKSPESREDPAHLS---DSSSSSSSIVSFKSADSIKSQPRIPRLAGDGGEH
T-SPEHRE-PGA----VRK-DNGVEHIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IRDEDRGPPPSAPPLLLSVIPGG
FIKQLVR----ETEQEAKAARQRKESRVGTKEEGAEGPQVSPPHQPSTPQVSEQGAGCPQ
VSQQAPLLCWQP---VGKDGEARAGGTSEG-PLRDGLKAEGQGAK-GVTAPPHKELPPEK
GVLGT-VPSKTPAPAPGSAAPAP--KPAETPPKKAETSPKTAAPAPKL-----AETPTKR
AE---TPCKPAETSSKPAETSPKPADTPRPGAPKVGKP--------------LWLGK---
-SPKD-SFLGGSPPAPAPAPS-----QGPQ-RGSKVPVKEGDVPKGTIPESTKGKGTVPE
TTKEKGTFPESTKEKGTVPESTKEKGTV------------------------------PE
STKEKGTVLEPTKEKGTVPESTKK--------------------EKGTVPGSTKKE----
---------------------------KGTPLRHEESPAKTKAQRELLSARKEPEKMKKD
VGGGKKEPREIKKPEKTTNKSEGLK-GEPGGIQEKSTDVGKEVEKVK------------E
----ELGEGKEMLK--------------ESKSIGKSTDKDQAEETSGRSKEMSK---SME
KDQDKEASGKSTDRDQAPRDVWYEAE---KVW--LIQQDGFTLAT---QLKPDMGTPELP
AGRVRVRRDQDGTVTEVDEDSVQR------------------------------------
------TNPPSLDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLAALISLNECSVLHTLQQRFRARLPCTYAGPSLVAIGPGPAP-
-------AGKVP----RGRRDNLP-PHICSLAHRAYRKLLLQRQDQAIVPLGHSGAGRTR
CCQSALEYLVGTAGSLDGRVS-VEKIQAMFTVLAAFGSVSTSHSSSSTRFSMVLSLDFSA
TGQVTAAHLQTLLLERARVAQQPEGESSFNIFPLLLAGLDVAERTMLHLHQVAESNSFGI
KPFTKPEDKQRASVAFSQLRAAMGTLGITPEEQAAVWRILAGIYHLGAAGACRV------
GRKQFLRFESASRAAEVLGCDVEELGTAVFKHHLRHILAQVTARGQPQA-------EEST
PGPKLTGVE-CVQGMASGLYEELFAAVVSLINRSFSSQHLSMASIAVVDTPGFQSPRQQR
RERAATFEELCHNYVQERLQGLFYEKTFLWEVER-YKEENVEVSFDLPERSPLATLSIID
LSCS-QPQVLP-GSPGAARRGLLWILDEEVLVPGSGDGTAFER-LCSYFATKGPDQ----
EGDGHLRRCEQTLQFEICHQLGTAPVRYDLTGWVSKAKFNLSAQNAIQVLQNSTVAAVRE
LLRPRASAPLPCRALAGLDGRSQPALHRNACLRKTFASSFAALRKRSVCAQIKLQADALT
NLLRRSQLHFVHCLLPGMGGEGPVLRP--PA--------PPDAAPQLDVVALRTQLEGTQ
LLDALRLHR---VGYSDRLL----LTQFRRRFQVLAPQVMKRHGSAYEVPDESKAVEELF
QVLDLEKKSVAIGRTQVFLKPGVISRLEKQRDKLIAQKMTLLQAACKGFLSRQKFKRLKI
QRLAVRCIQKNLQVFQAVRHWPWWQLLSHVRPLLSVSL

PF01576 // ENSGT00920000149027_1_Domain_5 (1719, 2313)

AEEQ-LRAKEEELAALRRKLEK
SEQACSELRQTTE-SLESKIIDLTTELSDERYKGDVTCQALDGERAERLRGTRELQELQS
KHEQVQKKLESVEKQLEEAQQLVQLREMKISGS-GGEDEWQVRFDCAQTEIVFLRRRLAQ
LEERLEAELGTRTGLEQKLGEAQAGCRAARDGARRLRRRCQRLACELEDARLLAENQQSR
SHELEKRQKKFDLQLAQALGQSAFEKSLREKLSQENTSIRWEMGK---LQQSLEHKEAEV
ARLEQQVAVLAGRVQELGSPG-AMD--TVPALKKKLWDLEGSAAEQKKELERQTAAVDHL
EQVHERLELEIERMKQIHQKELEDKDEELEDMQKSCQKRLRQLEMQLEQEHEQKQMVLHE
KQDLEGLIGTLCEQVGHRDFDVEKRLRRDLRRTRALLADVQLLLAAPAEPGGSAP----Q
LEHLHRQLEESEAKCAEAQRSQQTAAQELENLHTELETLSRSKTLVDEQLFQLQHERDDL
L--KRIDEDQEDLNELMEKHKALIAQSATDIAQIRELQTQVEDVQKEKQSLQE---KLQA
AQARAAQLEQCPAERSIVSRQEARIRDLESQLDFQAVQMKRFEVLVLRLRDSIIQMGEEL
EKAAESEARERENTRYYQRRMEEMKADMDELVQRELESSRRRMELEQQ-LAELAEVRQAL
QADLGTSIRRIADLQVALEGLRDSDDSDAGSVRTARESLCSGRDTDACSSVGSVLSLEPA
ESVKSWPSSSAGW--TSL-----ASASVAGSVAAPSLGSTQS--LRKHPGRAEA-V----
-----------------------------WGGAK----Q---SFNSSQAG----------
-------------QR----------PLGPR--LCQKQIITDFGRR-KGI-----------
-VEETKPHRRITPAMRRLSVAS-----GSLP-VASGPVP-SSAALSEYVEELRRQRGGGG
GG-------GGGGLGDPSPLPIYRTTGASALRRS-RALPAA---------EEPPGRLQGD
QAGEGASLARSSSLRSMASEPPA---GPRRLPPPAKFGSYDSLLPGLDGS---GRRPSSP
AA-G---MEVPRLSSWRSCLEPSLEDVELGKEPEGLLS-----SLSSDALGEGKASDPFS
WRIPTLNYERRTKVDFDDFVPAIRKSRSASSLARA-RRDRRDGHRPLTVRFEDEAVAGSP
DTKGTAKC---REEP-GDLSD-------SSSSGSRLSSRSADSVKRRPQPPRGGGEGSSG
----SATS--RRAE--AEGKEDDVSSIMKKYLGK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEEKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRKKQAVLASPEQETPEISTSQPNS-KSNS-DTKS-GSPK
ISQDNQASSPQNTDIPGQQSQG-PGPTEPT--QRTTINGEKAQESGPSAAPAKKPLPLKR
GVRRGDVLLMVAKLDPDSAKPEQRTQPRDAP------ACKTPSPA-------TDPGGGKE
GKAPPAPRGPQAS---TEDAALKAEKTQTGGPRDPGT--VPMTKGEKD---QGTAGKG-G
EAPQTKGLKGDEP-QGKEGPG----------EGGR-----------------------PG
TVEKRGADSTNKMAKGNLSKDAGGEGKL---AEGKLAGAQTQVKKWGGSLGR-SRWDGPQ
KK-DKEGALLRKAEKTGQSQVK-----A---------------EKVDKVQG---KVGEAP
GV-KEEARGPHSES-----------GEAGEAAA-----------------------KTQK
GCE--APQ---E---------VGAAG-KESHKVQEGCEAPKEVS-----------VAGKE
SRPDSRGQEAEGPCRSVNARA---GALETELQAPRPPALESHAERP-QRQ-ENQEGPALQ
EGSEGSQSGD-L--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTVTEVDEDHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

AEDLASLVSVNESSVLNTLLHRYRAQLSHTSTGPDLIVLQPHGPSA
PSA-----GKVP----KGRRDGLP-AHIVSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGSVS-VEKIRATFTLLRAFGSVSTGHSRSATRFTMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARQPEGEGTFEVFSQMLAGLDLDLRTELYLHQMADSSSFGM
GTWSKPEDKQRAAAAFAQLQGAMATLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPSRRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYTHERLQLLFYQRTFASTLEC-YREEGLPVQFDLPEPSPGTTVAIVD
QHPS-QVRLPP-GGGAADAKGLFWVLDEEVRVEGSSDSAVLER-LCAAFEKKGAGA----
EGTSALRPCEQPLQCEIAHQRGQDPVRYDLTGWLHRAKPNLSALDAPQVLQHSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSCAVRRTFASSFAAVKRRAPCSQIKLQMDALS
SVIRRSQLHFIHCLVPSLTVESRGGQGAPTPPQPDGDKPGAGGPLPLDIPALRVQLSGSY
ILEALRLHR---AGYADHMG----LTQFRRRFQVLDPLLTKKLMLATEGVDERKAVEELL
LTLDLEKKAVAVGHSQVFL

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KAGVVSRLEKQREKLV

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

SRTFVLFQAACKGFLSRQEFRKLKI
RRLASRCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGDEQ-LRAKEAELTTLRQKLEK
SEKSRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLRAFREVQELKG
KCEQVQQNLGEVEKQLQEAQQKIQLNDLEKSHT-GGADEWQMRFDCAQMENGFLRKRLQQ
FEERLDSELASRKELEQQLGELQSAYEGAKKTAHQLKRKCHRLTCDLEDTRFLLENQQSR
NHELEKKQNKFDMQLAQALGESVFEKGLREKVTQENTSVRWELGR---LQQQLKQKEQET
LKLKQEVETLQAQKRELLTLP-SRGENSVAGLKDRLWKLESNALEQQQIRNQQENTIQQL
EQLRQRLELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQVLLGTMEDGKVSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTADLESMHSELENMTRSKSLVDEQLYRLQFERANL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQLRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATAEAQQRESSQYYQRRLEELKADMQELVEREAEASRRCMELEKY-VEELATVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGG---SGRKEIDNVSILSSQPE
GSVRSWLSCTL--SVATDTMRSPSRQSAISSRI---LSPRH--RTHEEAGDAESVRR---
------------------------------------------------------------
--VS---ALSGA--QDAPSKTTGDKSLSSLLPLSLRRQKYCHFGHGDES-----------
-DIQRKPP---ERSGV-LSSSPSSQRGNTSPVS-REKLPSPSAALSEFVGGLRRQRAQRG
QG-------SVLGLEDWPTLPIYQTTGASTLRR-ARAGSAEGHLSLS-----SPLVTEDC
AG-PSAGLLRSTSLKCIPSQGGEG-TPLLPQRPKTRFSSCESLLESGPGS---GRKLSSP
SA-PRDTLLSPTLRPRRRCLESSLDDAGCPD--LGKEPLIFQNRQFAHLMGDPPDSDPFS
WKLPSLNYERKAKVDFDDFLPAIRKPETSRSLAGA-AKDGQDSSRHSSVHFETEE-AGRT
FLSGIKTILKKSPESKEDPGHLS---DSSSSSSSIVSFKSADSIKSRPRIPRPKGDEGER
T-SPGNRE-PGT----GRK-DEDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRRKAAAFTAPEVEIPAVPTNQTNK--TNN-VPKP-GSQQ
TSQDSSSTTQNSADIPGKEPPG-AGDKDST--PVTSTSGERPQESGPTGTPAKRTLPFKR
GVRRGDVLLMVAKLDPELAKADQKVQPRDVP------VDKTPAPA-------KDSGGTKK
GVTTGTSSAPQPS---M------PEKTRTRGVGDTGQ----STKGGKC---QGTEGKG-S
RDPQTIGQKEGES-QSTEEQGTRSQAQEAG-NKEQ-----------------------LG
TAEKEGGGPPKKMEKEDEPKVAGAEVR--------PVEPPVPLRKWGGFLGWRSKWDSPQ
SKDR-VTESHRKDEKTGDLQSP-----------AVDRSCGQLAEPTGQPSGPTGQPSGPT
GQLSESTGQPSGPTGQPAGPTGQPAGPTGQPAGPTGQPAGPTGQQQ-----EAPVKMEGK
VGRPQKKL---VTPRKPREL-PGVAA--KTQNPEESCKAPDRIPTTG----ISAEAAKRD
GQPESRVQGAGEPRVCTEEEV---DVVKPQAEGHVESIPEVVMERL-STLRPMEEKQILQ
DPDRGGQSGD-SDQA-Y-EDRWYEAQ---KVW--LVQKDGFTLAT---VLKPDEGTADPP
AGRVRLCIDADRTVIEVDEEQVHP------------------------------------
------ANPSELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLVSVNESSVMNTLLQRYRAQLPYTCSGPDLITLQPQTTTV
PSS-----GKVP----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKLRATFTVLRAFGCVSTGHSRRATRFAMVMSLDFNA
TGRVTAAQLQTVLLENSRVARQPQGEGNFEVFSQLLAGMDVDLRTELNLHQMAESSAFGM
GLWSKPEDKQKAATAFSQLRGAMELLGISEGEQQAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCDYEELNTATFKHHLRQIIEQMTSGPQRQG---LQ-DNEAC
SGLKMTGVE-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDTPGFQNPRHQG
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YKEEGIPVPFDLPESSPGTTVAVVD
QNPS-QVHLPA-GRGAEDAGGLFWVLDEEVRVQGSSDSTVLER-LRAAFEKKK-EAGA--
EEPPSMRTCEQPLQCELFHQLGRDPVRYDLTGWLRRAKPNLAALEAPQILQQSKREELQS
LFQARAKLPPVCRAVAGLEGTSQQALHRSRVVRRAFASSLAAVKRKAPCAQIKLQMDALI
SLLRRSRLHFIHCLVPTTV-ESKAGQRTPSPSQPSGDQGVANEPTALDIPALRVQLAGSH
ILEALRLHR---AGYAEHMG----LAQFRRRFQVLDPALLKKLDLTSEELDERKVVEELL
KTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSRNIVLFQAACRGFLSRQEYKKLKI
RRLATLCIQKNLAVFLKVKDWPWWGLL

PF01576 // ENSGT00920000149027_1_Domain_5 (1708, 2143)

ASLRPLLSSTLGTEQ-LRAKEEELTLLRQKLQK
SENSRSELRQNTD-LLESKITDLTSELADERFKGDVACQALESERAERLQALREVQELKT
KYQQVQDALGEVQKQLEEAQQRIQGANLEEKPA-GGADEWQMRLDCAQMENDFLRKRLQQ
CEERLDSEMKARTELEQKLGELQSAYEEAKKMAHQLKRKCHHLTWDLEDTRVLLENQQSR
NHELEKRQKKFDLQLAQALGESMFEKSLREKVSQENNGVRWELGQ---LQQQLEQKEQEA
SKLKQEVERLQGQKRELLSCA-SVGDQGVASLKERVWELETNALEQQKIHSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQVALHE
KHDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATIEDSKTSIS--KEE
LEKVHSQLEQSEAKCEDALKTQKVLTADLENMHSELENVTRSKSLVDEQLYRLQFERADL
L--KRIDEDQGDLNDLMQKHKDLIAQSAADIGQIQELQLQLEETKKEKQKLRE---QLHM
AQLRIQYLEQSTVERAIVSRQEAIICDLENKTEFQKVQIKRFEVLVIRLRDSMIKMGEEL
SRAVKAEAQQRENSQYYQQRLEELKAEMQELAQREEEASRRCMELEKY-VEELATVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDTESVQTAVDCSS---RSGKEGDNVSVISSQPE
GSLQSWMSCSL--SLATDSVRIPSGQSVVSSSF---HSPRV----SEEAGDSERLRT---
------------------------------------------------------------
--ASS--ALSGAWDAARDASKAGSASL-----HPVFPQKPYHLGDGEGF-----------
-AVHRKST--LERSGP-LSSSPPSQRTAVSPPS-RDKLPSPSAALSEFVEELRRKRAQRG
QG-------STLHLGDGPVLPIFQTTRASSLRR-GRASSDEGDLSLKTR-VKSPLGAEGI
PGA-TAGLSRSTSLKCISSEGPED-ITLLPDKQKTRFGSCESLLESGPCT---RRKLSSP
T-----GLLSPTLRPRRPCLESSVDDAISLE--LGKEPLVFQNRQFSHLMEETLDSDPFS
WKLPSLNYRRQTKVDFDDFLPAIRKSDTPSSGA---AKDGKEASKHPGVHFEMGEAADRS
FLSGIKTILKKSPEVKEDPAHLS---DSSSSSSSIVSFKSTGGTGSGPRVPRLQGDGGER
M-SPEHRD-PGS----ARR-DDDVESIMRKYLQQ-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRRKEAVLASPEQETPEVSVNQSNS-KTNS-GTKS-GSQQ
TSGDSQSTSLQGTSIPGKDNQH-SGTADPA--LMTSVNGERHQEPGPGGIPARKALPFKK
TVRRGDVLLMVAKLDPEATKPEHRNQAHDTP------TCKTPPAA-------TDPGGAKE
GETPGT-SGPQAS---TEDLASKPEKTLTGGHGDPGQ----GMKGEKG---QGTVGKG-S
GGLQTKGPKGGEP-KDKEEQRTRPQSRGAG-DGGQ-----------------------LG
TVEKEGGDPPTKMEKRNES-----KDMG---AEGKHAGPRVQGKKWGEFLS-RSKWDGPQ
SKKDRESELPGMAEKTGKPQAKM--------------------EERGKVQGKAGQAGEAL
QTLGKAAEPGKASE--------------------------------------A--PKSEE
VGQPQRKA---A----------G-T-GRAGSQADKGCKVPKEVAIER----VSPAVTEPE
DRPESRAQRAEKPCTKVEDAA---GGPEPQQEGCAEPSLETRVEKP-PGQTQAQEGPTLQ
DQGRGGHS---GGLGQAHEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTVTEVDEEHVHR------------------------------------
------ANPPELDY

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

VDDLASLVSVNESSILNTLLQRARAQLLQTCAGPDLIVLQPQGSMA
PSS-----GKVP----RSRRDGLP-AHVSSLAQRAYWAMLSQRRDQSIIALGRSGAGKTT
CCEQVLEHLVGMAGCVDGRVS-VEKIQATFTILRAFGSVCTGHSCSATRLAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVVRPLEGEGNFPVFSQMLAGLDLDLRTELYLYQMADSSSFGM
GMWSKPEDKQKDVAAFAQLQGAMETLGITEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIAQVTTGPSRRG---LK-DEEPS
SGFKMTGTE-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYIHERLQLLFYQRTFISVLER-YQEEGIPVPCDLPEFSPGTTVAIVD
QNPS-QVRLPT-GGRTEDARGLFWVLDEEVQAEGSEDSVVLER-LRTAFEKKGAGAK---
-GTSALRTCEQPLQCEIFHQLGQDPVRYDLTGWLHRAKPNFSALDAPQLLQQSKREELQS
LFQGRAKLPPVCQAVAGLEGTSQQALHRSRVVRRTFTSSLASTRRRAPCSQIKLQMDALI
SLVRRSQLHFIHCLVPTPALDNKGGQESSAPPLP-GDQQEASKPLAPDIPALRVQLVGSH
ILEALRLHR---TGYADHMG----LSQFRRCFQVLDPALLKKFMSVPEGIDERKAVEELL
ETLDLEKKVVAMGHSQVFLKAGVVSRLEKQREKLVSQNIILFQAVCRGFLSRQEFKKLKI
RRLAAQCIQKNVAMFLALKDWPWWQLLG

PF01576 // ENSGT00920000149027_1_Domain_5 (1709, 2140)

SLRPLLSATVGNEQ-LRAKEEELTMLRQKLEK
SEKSRNELQQTAD-LLESKIADLTTELADERFKGDVACQVLENVCAERLQASREVQELRN
KYEQVQKNLGEVERQLEEAQQKIQLNDLERKHT-GGADEWQMRLDCAQMENEFLRKRLQQ
SEERLDSELTSRKELEQKLGELQSAYEEAKKTAHQLKRKSHRLTWDLEDTRVLLETQQSQ
NHELEKKQKKFDMQLAQALGESVFERSLREKAIQESSSMRWELGQ---LQEQLEQKEQET
LRLKQEVEMLQKHKQELLASP-SLGASGVASLKERLWKLESSAQEHEKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGSLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLVTVDDGKTSVS--KEE
LEKVHSQLKQSEAKCEDALKTQKALTLDLESMHSELENMTRSKSLVDEQLYRLQFERADL
L--KHIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRLEVLVIRLRDSLIKMGEEL
SQAVASESQQRESSQYYQRRLEELKVDMEELLQREAEASRRCMELEKY-VEELGAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDT------------------ER-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-----------------------------------

------------------------------------------------------------
---------------------MAISSRLALWEQK---ERQE---PSTVLAPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALAAPERETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-TGSPDPE--GMTSINGEKAQELGSTATPAKKTLPFKR
GMRRGDVLLMVAKLDLDSAKPER-THPHDTS------PCKTPPPV-------TDTGKERK
GETSRAPCGPQAS---TEILAPKAEKTWTGGLGDAGQGTVALKKGEKG---QSIVGKG-G
GTPKTKELKEAEP-QGKDRQGTRPQAQGPS-EGVR-----------------------PG
KAEKEGGEPTSPVEKENVSKNVGSEGK--------HIGPHIPGRKWGGFLGRRSKWDGPQ
NKKDKEAVLLSKAEKTGEPQTQ-----T---------------EKKSQMQGE---LGDDL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAEGPCSREDVGS---GALETELEGPSQPALEKDAERP-RIQKENQDGPAPQ
EAGKGGQSRN-S--EQASEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRWDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTA
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRMELNLHQMADSSSFGM
GMWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRD---LE-DEETS
SGLKITGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPDLSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQSRAKLPPVCQAVAGLEGTSQQALQRNRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVLNPVVESRSEQESPTPPQPGRDKPGADAPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAMFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
LQLKQEVEMLQDHKRELLGSP-SLGENCIAGLKERLWKLESSALEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTMRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----LSRAWSTDVHSKTSGNKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKSA---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYLTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQMPTSLAGA-AKDGQDGSQRSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVTSIMKKYLQK-

------------------------------------------------------------
-----------------------------------KQIREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRRKEAELASPERETPDISTSQPNS-KSNS-GAKS-GSQQ
IPQDSQPSSAQDSSILGKEREG-AGPADPM--LMTSINGEKPQESGPGGTPAKKPVPFRR
GIRRGDVLLMVAKLDLDAAKPEQRAQPRDGP------TCKSPPPA-------TDPGGEKK
GETPGPPRGPQAS---TEDAAPKAEKTQTGGLGDPGQK---------A---QGTGEKG-G
GAPQTKGPKGGEG-N--EGPG----------EGGQ-----------------------PR
TAEKGAGDPPTEMAKGKLSKDAGGEGR--------WAGAQIQMRRWGGSLGRRSKWYGPQ
SKKDREGDLLSKAEKTDGPQIK---------------------TETGNAQGKVGKVGEAP
RL-TEKA---------------------GEPLG-----------------------EMGK
VGQPQGE--------------AGEAE-RAGSKTEKGWEAPKEADARG----ETPAAARNA
GRPDRKGQKAEEPCARVDVGA---KALETLLAGPRPPALESQAERT-QTHKENQEGPALQ
EGGNGGQSGA-SDQDQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1516)

DDLASLVSVNESSVLNTLRHRYEAGLLHTWTGPDLIVLQPRGSPA
PSA-----GKVP----RCRWDGLP-AHVGSLAQRAYWALLNERKDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGTVS-VEKIRAVFTVLRAFGSVSTSHSHSATRFTMLMSLDFNA
TGRVTAAQLQTMLLEKSRVARQPEGEGNFEVFSQMLAGLDLDLRTDLYLHQMADSSSFGM
GTWPKPEDKQKAAAAFAQLQGAMGTLGISESEQRAVWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANRAAEALGCEYEELNTATFKHHLRHIIEQVTSGPNRRG---LE-DEETS
SGLKMTGRTDHVAGLCSEPMLREVKFHVVSLPRSLSSHHLSMASITVVDPPGFQNPRHQG
KERAATFEELCHNYAHERLQLLLHQLTFVSALER-HREEGVPVQFDLPEPSPGTTVAVVD
QSPS-QVRLPA-GGSTEDAGGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGA----
DGMSALRTCEQPLQCEISHQLGRDPVRYDLTGWLHRAKPNLSALGAPQVLQQSNREELRR
LFQARAKLPPVCRAVAGLEGASPQALQRSCVVRRTFASSFAAVRRRAPCSQIKLQMDALT
SVIRRSQLHFIHCLL

ENSGT00920000149027_1_Linker_1_3 (1516, 1549)

PGPVVEGRGGQGSSTSLQPGGDQPRAGGPLPLD

PF00063 // ENSGT00920000149027_1_Domain_3 (1549, 1640)

IPALRVQLAGSC
ILEALRLHR---AGYADHMG----LTRFRRRFQALDPLLMKKLMLATERIDERKAVEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLEKQREKMLIHSIVFFQATCKGFLSRQEFKKLKI
HRLAAQRIQKNMAVFLAVKDWPWWKLLGSLRPRLSTAIGDEQ-LHAKEEELTMLRKKLER
SEKSRNELRQSTD-LLESKIADLTTELADERFKGDVACQVLESERAERLRAFREVQELKS
KYGQVQKNLGEVQKQLEEAQQKIQLNDLERSHT-GRADEWQMRFDCAQMENEFLRKRLQQ
FEERLDSELTSRKELEQKLGELQSAYEGAKKTAHQLRRKCHRLTCDLEDTRLLLENQQSR
NHELEKKQKKFDTQLAQALGESVFEKGLREKVAQENTSVRWELGQ---LQQQLKQKDQEA
VQLRQEVEMLQAHKRELLASS-SLGENCVAGLKERLWKLESSALEQQKIQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDIRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTADLESMHSELENMTRSKTLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSATDIGQIQQLQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAIICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQATTSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEIDNISVVSSQPE
GSLQSWLSCSL--SLATDTMRSPSRQSAISSHI---LSPRM----NEEVGDAEKTQG---
------------------------------------------------------------
--AS---ALSG--ARDMPSKSSGDKSV---SPLSLRRPKYCHFGEGEEC-----------
-GAQRKPT---ERLGA-PSSSPASRSTNSSPSS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------SALSLEDWPTLPIYQTTGASTLRR-ARAGSDKGDLSPRL-RAKSPLETQAT
AG-TSAGLLRSTSLKCISSESAEG-TALLPEKLKTRFSSCESILESGPGS---GRKARSP
TM-PRDTFLSPTLRPRRRCLEASLDDAGCPD--LGKEPLVFQNRQFAHLMGEPLGSDPFS
WKLPSLNYERKTKVDFDDFLPAIRKPETPTSLARA-AKDGQDRPQHSSVHFETEE-ADRT
FLTGIKTILKKSPESKEDPALLS---DSSSSSSSIVSFKSADSIKSRPRIPRLEGDGGER
T-SPENRE-PGA----GRK-DEDVESIMKKYLQK-

------------------------------------------------------------
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------------------------------------------------------------
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-----LRKCEQ

PF00063 // ENSGT00920000149027_1_Domain_2 (1392, 1637)

EVQFEVGHLLGHDPVRYDATGWVSKAKWNLSAENAAQVLQQSRIEAIKE
LFQGRCKVPLVCRSVAGLEGTSQQALQRIGCVRKTFASSFAAVKKKSVCAQIKLQLDALC
NLVKRSQIHFVHCLLPTTETETQP-----------------DPTTLWDIPSLRVQLSGGQ
ILDALRFHR---IGYADRMA----LTQFRRRFQILAQPLMRKYTSAYETTDEKKALEELL
RALDLEKKSIALGRTQVGKAKGQDGLP-KS----VS------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRKKQTPAGSQEQTAPENSDSSANRSHTPS-GTQSPQGGQ
PDPASPSPNVVVANIPN---ES-EGMASPEPVLMSSINGEKPQEKGTMETPPRKPQPFKR
SRKTSDVLLMVAKLNSELPKPEQRTHPVDSP------THKPPPSV-------PELEGEKK
GEPPGDTHDPQTA---TEASAEKMEKLRSQGLGSPGSTDLPSKKSEKP---TIKLSKW-G
KVSQTKGLKGGES-QSKEELGTKPHTKEGEQRSEA-EVKGTEEVKAQIPQT-EEEGQ-LH
PKAELGDKSQGRPGKAGHPKDTVETGKEAHSKAGKGDRAQIQMKKWGESLSRWRKRSESQ
SQMGKGNEPQSQVGKDSESQTQVRN-----------------------------------
------ENEPQSQVGRESGPQSQLGKEYGS---------------------------QGH
VGKDHE-------KGSCSQIKESKED-GPYQKGKSGSEVLK----EGMEIHGSP------
---------------------------ITEKEGIAPETKKEGEETPVKM------EEEEE
EEKKDGERGHSVHSDKELEDRWYEAE---KVW--LVQKEGFTMAT---ILKPDVGTPELA
AGRVRLCIEADKSITEVNEENIHR------------------------------------
------ANPPELDLA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

ENLASLQSLNESSVLNTLQHRYQAQLLHTYTGPDLIAFQPQGPPA
PSS-----WKVSFLINGGRREGLP-PHICALAHKAYWAMLSQRQDQTLVPLGRSGAGKST
CCERALEYLVGSAGSLDGQVS-VDKIRATFTILRAFGSVLTAHNGSSTRFSMLMSLDFNA
TGRVTAAHLQTMLLERVRVAQQPEGEGNFAVFSQMLAGLDLDLRTELYLHQMADSHSFGM
GVWAKPEEKQKAAAAFSQLQGAMVTLGISGTEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEVLGCEYEALTTAVFKHHLQQIIQQATARSLLER---HL-LLLLG
AGPKMTGVE-CVEGMASGLYEELFAVIVSLINRSLASGHLSTSSIMVVDGPGFLNPRHQK
KERAATFEELCHNYAQERLQALFFQRKFESELER-YREEKVVVPFDLSELSPRTTVAIID
QNLS-QVRVPV-AGQAEEPKGLLWVLDEEVRIEGSGDSAVMDR-LCLAFEKKEAGA----
DESPAFRKCEHALQFEISHQLGQDPVRYDLNGWIQKAKPNLSAMNAIQVLQQSKREDLSS
LFLPRSKVPPVCRAVAGMEGRSQQALNRIGCVRKTFSSSLAAVKRKAVCAQIILQMDALT
NVIKRSQLHFIHCLIPRSGLEKKGGSTSLAPAQ---------RDQPLDFSILRVQLAGAQ
VLDALRLHRIGKYG--AHKI----KKSIE------RRVFITKKNNREEGSMEDGLVEELL
QELDLEKAAVLIGNTQVFLKSGIISRLERQREKLASRNIILFQAACKGFLSRQQFKKLKI
RQLAVQCIQRNLAVFQVVKDWPWWQLLCYIRPLLSVTIGEDQ-LRAKEEELTALRKKLEK
SEKSRNELRQNTD-LLESKIADLTTELSDERFKGEVACRVLESERAERLRASREIQELKS
KYEQTQKSLGSVEKQLEEAQQKIELSGCLPL--SSTDDDWRTRFDCALTEIEFLRKRLLM
YEERIESELVARRELEEKLREAVNSYEEVRKSSHQLKRKCHSLTFTVMDELMFIIGESFR
THPIQLLPHLFDMQLTQAIGESLFERGLREKLSQENASAQWELGQ---LQSRLEETERES
VGLKQKLEMLRCYNVDQRSSPLPCGVEAVAALQRQLWDLKSSALEQQQIQNEQETTIKKL
EQLRVRFEMEVERMKQTYLKDQEDKEEELEDIRQSCQKRLRQLEMQLEQESEEKKLVLHE
KQDLENLIGTLCEQIGHRDFDVEKRLRRDLRRTHALLSDVQFLLTNIEDSQTIVN--KEE
LEKVHKKLEESETKCADAQNTQKLLAQDLENMHSELENVTKNKNLVDEQLFRLQLEKTDL
L--KRIDEDQEDLNELMKKHKDLIAQSSQDIMQIQELQQSLEEAKKEKQNLQE---KLTI
AQSRVEHLEKTMVDRSIVGRQEAVICDLENKLEFHKVQIKRFEVLVLRLRDSALKLGEEL
EKAVCSEIAQKESCQYYQRRMEEMKVEMAELREKETDTSHRCLDLEKR-VEELLAVRLTL
QADLEVSIRRIADLQMALEDVDSS-NSDNERDN--------------QSFPESSISSQPM
ESVRSWLNLSPNQSRSNSTVRSESQQSATGSGV---LDQRM----HRETRDAEKKQPALR
TEA--PGDYE--------------------------------------------------
------KPLAESF------------ARQPISPFTFPGPDYNKTNKVESS-----------
-ET-----------RKKTSNKSKSHSSTTSPTL-DKKPPSTSWALSEFLEGLRKKQSDKE
KD--------ALGEEDWPTLPIYQTIGATSLRRSLETATLPEKGAL-----------EID
PDSPRSGLLRSTSLKCLSCDNSES-FLSLPLPSKSVYRSCESLLQSENLENTFNRNLSSS
VGDNLGKFSQSRLHLRRPCIDTPLEEVEDPD--LGKESLVFQNRRFSNLPDEPLEPNFRD
WKLPR--YEQKSKVTFDDYVPAIRKSKSPIRASK----DRGDGLKSGATFFKSD-ASSEC
LFPGTSSTFQEDLESKEDTGHLS---DSSSSSSSAMSYRSADSIKSRPGSLKRDEESERR
S---------RYGTWMDAKRQDEVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARLRKEAALASPEQETPEISASQPKS-KSDS-GTKS-GNQQ
ISQGNQLSSPQNSDIPGKESKG-AGTTDSV--LMTSINGEKPQESGPTGTPARKPLPFKR
GVRRGDVLLMVAKLDPDAAKPEQRTQPRDAL------ACKTPPPA-------TDPGGEKK
GGTPGTPRGPQAS---TKDTATKAEKPRTEGVGDPGM--VLLT----K---QGAGGKG-D
GAPQTKGLKGDEL-QGREGPG----------QGEQ-----------------------VE
TAEKGAEDPPSKMAKGNLSKDVGGEGK--------RAGAQIQVRKWGGPLGRRSKWDGPQ
SKKDKESVLPSKAEKSEEPQIK-----V---------------EKGSKEQEKAGKGGDAP
RE-VGKAGEHPSAP-----------GKSGEPGA-----------------------KVG-
KGQPQGE--------------SREAG-EAAGKTEKVWKAPKEVGARG----ETPAAAEKE
GGPHSAARKAGEPRSGAADGA---EALEMEVEGPRPPARDGPTERP-RSRRESEEGPGLP
EGSRGAQSED-S--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1516)

EDLASLVSVNESSVLNTLLHRYRAQLPCTFKGPDLIVLQPPGPPA
HSA-----GKVL----RGRRDGLP-AHLGSLAKRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVAMAGSVDGRVS-VEKIRATFTILRAFGSVSTSHSCSATRFAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARQPEGEGNFEVFSQMLAGLDLDLRTELYLHQMADSSSFGM
GVWPKPEDKQKAAAAFAQLRGAMETLGISEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPSRRD---PE-EEETS
SGLKMTGVE-CVEGMASGLYQELFAAVISLINRSFSSHHLSMASIMVVDSPGFQNPRHQC
KDRAATFEELCHNYAHERLQLLCHQRTFVSTLER-YRQEGISVPFDLPETSPGTTVAVVD
QNPS-QVRLPA-VGGAEDAKGLFWLLDEEVRVEGSSDSVVLER-LCAAFEKKGAEAGGLL
SGTSALRSCEQPLQFEIFHQLGQDPVRYDLTGWLHKAKPNLSALDAPQVLQQSKREDLRL
LCQPRAKVPPVCRAVAGLEGTSQQALQRSCAVRRAFASSFAAVKRRAPCSQIKLQMDALT
SIIRRSQVHFIHCLV

ENSGT00920000149027_1_Linker_1_3 (1516, 1551)

PGPVGESRVGQGPLTPPQPGRDKPGTGGLLTLDIP

PF00063 // ENSGT00920000149027_1_Domain_3 (1551, 1640)

ALRVQLAGSH
ILEALRLHR---AGYAEHVG----LTQFRRRFQMLDPLLAKKLMLASEGIDERKAVEELL
QTLDLEKKAVVVGHSQVFLKAGVVSRLERQREKLASHRILLFQAACKGFLSRQEFKKLKI
HRLASQCIQKNVAVFLAVKDWSWWQLLGSLRPLLSSTIGDEQ-LHAKEEELTMLRQKLEK
SEKSRNELRQNAD-LLESKIADLTTELADEHFKGDVACQVLESERAERQRAFREVQELKS
KYEQVQKNLGEVQKQLEEAQQKIQLSDLGRSHT-GGADEWQMRFDCAQMENEFLRKRLQQ
FEERLDSELTSRKEVEQKFGELQSAYEEAKRTAHQLKRKCHYLTCDLEDTRLQLENQQSR
NHELEKKQKKFDMQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQET
SQLKQEVEMLQAHKQELLGLS-SLGENCVAGLKDRLWKLESSALEQQKIQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGSMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALAADLESMHSELENMTRNKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSATDIGQIQELQLQLEEAKKEKHKLQE---HLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
TQAAKSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDTESVQTAVDYSS----GRKEIDNVSILSSQPE
GSLQSWLSCTL--SLATDTMRSPSRQSASSSHI---LSPRM----NEEAGDAERSQA---
------------------------------------------------------------
--AS---ALSRA--RTVQSQTSGDKSV---SPLCLRRQKYYHLGDGDER-----------
-GGQRKST---ERLGA-RSSSPASQSADASPAS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------SPLGLEDWPTLPIYQTTGASTLRR-ARAGSDAGDLSLRPGAKAAAPEPQGA
CGTSSAGLLRSTSLKCISSQGTEG-TPLLPEKLKTRFSSCESLFESGQNV---GRKLSSP
ST-ARDTLLSPTLRPRRRCLESSLEDAGCPD--LGKEPLVFQNRQFAHLMGESLDSDPFT
WKVPSLNYERKTKVDFDDFLPAIRRPETPVSLTRA-AKEGPDSPRRSRIHFETEE-ADRN
VLSGIKTILKKSPESKEDPAHLS---DSSSSSSSILSFKSADSIKSRPRMPRLEGDGGER
T-SPEHRE-PGV----GTK-DEDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRRKEAGLTSPEVETPAVPTNQSNK--TNN-VPKP-GSQ-
TSQDSSSTTHDSADIPGKQPPE-PGDKDST--PVTSTSGERPQESGPTGTPAKRTLPFRK
GVRRGDVLLMVAKLDPELAKAEQKIQPRDVS------TDKTPAPA-------KDSGGTKK
GMITGTSCDPQAS---M------SEKTRTRGVGDTGQ----SIKGGKC---QGTEGKG-S
RDPQTKGQKEGES-QNTEEHGTRSQTQEAG-NKGQ-----------------------QG
TAEKEGGGPPKKMEKEDGPKVAGAEVR--------PLEPPVPLRKWGSSLGRRSKWDSPQ
SKNR-VTESRRKDEKTEDKQSPKEEKMEDKQSLAVDRSCGQPAEPT--------------
------------------------------------------GQQP-----ESPAK-MGK
VGRPQKKL---VTPEKTREL-PEVAA--ETQSPEESCKARDGIATEG----TSAEAAKRE
GQPESRMQGAEEPRVHTE-EV---DVTEPQAEGRRESVPETGMERP-SMQKPMEEKQILQ
DPDRGGQSGD-SDQA-F-EDRWYEAQ---KVW--LVQKDRFTLAT---VLKPDEGTADLP
AGRVRLCIDADRTVTEVDEEQVHR------------------------------------
------ANPSELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1519)

EDLAFLVSVNESSVLNTLLKRYQAQLPHTCSGPDLIALQPQTTTV
PSS-----GKVP----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKLRATFTVLQAFGCVSTSHSRRATRFAMVMSLDFNA
TGRVTAAQLQSMLLENSRVARQPQGEGNFEVFSQLLAGLDVDLRTELNLHQMAESSAFGM
GLWSKPEDKQKAATAFSQLRGAMELLGILEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCDYEELNTATFKHHLRQIIEQMTSGPQRQG---LQ-DNEAC
SGLKMTGVE-CVEGMASGLYQELFVAVVSLINRSFSSQHLSMASIMVVDTPGFQNPRHQG
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YREEGIPVPFDLPESSPGTTVAVVD
QNPS-QVHLTA-GRGIEDAAGLFWVLDEEVRVEGSSDSVVLER-LHAGFEKK--ASGA--
EEPPSMRTCEQPLNCELFHQLGRDPVRYDLTGWLRRAKPNLSALEAPQILQQSKREELQS
LFQARAKLPPVCLMVAGLEGTSQQALHRGRVVRRAFASSLAAVKRKAPCAQIKLQMDALI
SLLRRSQLHFIHCLVPTT

ENSGT00920000149027_1_Linker_1_3 (1519, 1552)

V-ETKAGQGTPTPSQPGGDQGGANEPPAPDIPA

PF00063 // ENSGT00920000149027_1_Domain_3 (1552, 1640)

LRVQLAGSH
ILEALRLHR---AGYAEHMG----LAQFRRRFQALDPALLKRLDLTSEGLDERKAVEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSRNIVLFQAACRGFLSRQEYKKLKI
RRLAALCIQKNLTVFLKVKDWPWWGLL

PF01576 // ENSGT00920000149027_1_Domain_5 (1708, 2144)

ASLRPLLSSTLSTEQ-LRAKEEELTLLRQKLQN
SENSRSELRQSAD-LLESKIADLTSELADERFKGDVACQALESERAERLQALREVQELKA
KYQQVQDALGGVQKQLEEAQQRIQTANLEEKPT-GGADEWQMRLDCAQLENDFLRKRLQQ
CEERLDSEMKARTELEQKLGELQSAYEEAKKTAHQLRRKCHHLTWDLEDTRVLLENQQSR
NHDLEKRQKKFDLQLAQALGESMFEKSLREKVSRENSGVRWELGQ---LQQQLEQKEQEA
SKLKEEVERLQGQKRELLNCA-SVGNQGVASLKERVWELESNALEQEKVRSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQAALHE
KHDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATIEDSKTSIS--KEE
LEKVHSQLEQSEAKCEDALKTQKVLTADLESMHSELENVTRSKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNGLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLWE---QLQV
AQLRIQYLEQSTVERAIVSRQEAIICDLESKTEFQKVQMKRFEVLVIRLRDSMIKMGEEL
SRAVKAEAQQRENSQYYQQRLEELKAEMQELVQREEEASRRCMEMEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCSS---RSGKEGDNVSVISSQPE
SSLQSWMSCSL--SLATDSVRIPSRQSAISSSL---HSPRV----SEEAGDSERPRP---
------------------------------------------------------------
--AST--VLHGDWDAPRDTAGAGSVSL-----HPVLPQKPYHLGDGEGF-----------
-AVHRKST--PERPGS-LSSSPTSRSEVVSP------LPSPSAALSEFVEELRRKRAQRG
QG-------STLHLGDGPVFPIFQTTGAFSLRR-GRASSDEGDLSLRTR-VKSPLGAEGN
AGA-TGGLSRSTSLKCITSEGAEG-ITRLPDKQKTRFGSCESLLESGPST---RRKLSSP
T-----ALLSPTLRPRRPCLESSVDDAACLD--LGKEPLVFQNRQFSHLMEETPDSDPFS
WKLPSLNYRRQTKVDFDDFLPAIKKPDVALSGA---SKDGKEASKHPGVHFEMGEAADRS
FLSGIKTILKKNPEAKEDPAHLS---DSSSSSGSILSFKSTDGMRGGPRVPRLQGDGGER
M-SPEHRE-PGS----LRR-DDDVESIMRKYLQQ-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARLRKEAALASPEREIPEVSTGQPST-G-----TKP-GI--
--QNAKSGSPLSADILGRKGEE-AGTMDPV--LM-TINGEKPQESGPSGTPAKKSLPFKR
GVRRGDVLLMVAKLDPDSARPEQRTQPRDAP------TSRTPSPA-------TDPGGGKK
GDIPGTPRGPQAS---TTDAPLKAEKTQTGGPGDP--GTVLPTKREQD---RGTVGKG-G
EAPQTNKVKKAEL-Q---------GKEGLG-DGGQ-----------------------PG
TAEKGAGDSPNKGAKGSLSKDVAGEGK--------WAGAQAPVRRWGGSLGRRGKWDRPQ
REKDKEGVLLSKADQMEEPQAR-----A---------------EKAGKAP---GKAGEAP
RA-MDKAGEPQSRT-----------GKAGEPRG-----------------------KMEK
TGPPQSA--------------SGEAG-KAGGEAEKDDKAPKEVDARG----VTPTTAGKE
DQPESRGQKAEEARPGA-------GSLELEPGGPGQPALDGHEEKS-------QRPTESQ
EGRGGGQSGV-S--GQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCVDADGSVTEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1519)

EDLASLVSVNESSVLNTLLHRYQAQLPHTHAGPDLIFLQPQGLMA
PSA-----GKVP----RNRRDGLP-AHISSLAQRAYWALLSQRRDQSIVTLGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRAAFTVLRAFGSVSTGHSRSATRFAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARQPEGEGNFEVFSQMLAGLDLDLRTDLYLHQMADSSSFGM
GLWPKPEDKQRAAAAFAQLQGAMEMLGISDGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPSRRS---LE-GEEAS
SGLKMTGVE-CVEGMASGLYQEVFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
RDRAATFEELCHNYIHERLQLLFYQRTFVSALER-FREEDVPVQFDLPESSPGTSVAVVD
QTPS-QVRLPA-GGGAEDSRGLFWILDEEVRVEGSQDSVVLER-LCAASEKKGAGA----
EGASALRACEQPLQCEIAHQLGHDPVRYDLTGWLHRAKPNLSALDAPQVLQHSNREELRT
LFQSRAKLSPVCRAVAGLEGTSQQAQQRSCAVRRTFASSLAAVKRKAPCSQIKLQMDALI
SVIRRSQLHFIHCLVPSA

ENSGT00920000149027_1_Linker_1_3 (1519, 1546)

AVESRGVQGSPTPPQPGGDKPEAGRSL

PF00063 // ENSGT00920000149027_1_Domain_3 (1546, 1640)

PLDIPALRVQLAGSY
ILEALRLHRADTPGYADHMG----LTQFRRRFQVLDPALVKELISAPEGVDERKAVAQLL
QTLDLEKKAVAVGHSQVFLKAGVVSRLEKQREKLVSQSIVLFQAACRGFLSRQGFKKLKI
HRLAARCIQKNVAVFLAVRDWPWWRLLGSLRPLLSATIGEEQ-LRTKEAELTALRQKLEK
AEKSRNELRQNAD-LLESKITELTTELADERFKGDVACQVLESERAERLRASREVQELKS
KYEQVQKNLGEVEKRLEEAQQKIQLNDLERSHT-GGADEWQMRFDCAQMENEFLRKRLQQ
SEERLESELASRNELEQKLGELQRAYEGAQRTAQQLKRKCQLLTCDLEDTRFLLESQQSR
NHDLEKKQKKFDAQLAQALGECVFEKGLREKVAQENTSVRGELGK---LQQLLKQKEQES
LQLKQEVEMLQAQKQELLRSP-SLGENCVAGLKERLWKLESSALEHEKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDKEEELEDVRQSCQRRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVQSQLEQSEAKCEDALKTQKALTADLENMHSELESMTRSKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEARKEKNKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAAAAESQQRENSQYYQRRLEELKADMEELVQREAEASRRCMELLLHVVSELARVTSRL
SADLPSADSHCANGEPCVENVTHS-DGDEAVVQTAVDCGGG--SGRKEIDNVSTLSSQPE
GSLQSWLSCTL--SLATDTARTPSRQSAISSRI---LSPRT----HEEAGD---------
------------------------------------------------------------
------------GARDVHSRTSGDKAA---SPLSRRQGTYGHFGDGEEC-----------
-GVQRKAP---ERPGA-PP-SQASRSGDASPLP-RDKLPSPSAALSEFVEGLRRQRAQRG
RG-------SPLGLEDWPTLPIYQTTGASTLRR-ARAGSDEGALALRAG-AGS------A
LD-ASAALPRSTSLKCIPSQSAGS-PSPPPEKLKTRFSSCESLLESGPSS---RRTPSSP
AAARRDPLWSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMGDPLGSDPFS
WKVPSLNYERKTKVDFDDFLPAIRKPETPTSLPRA-AKDGRDSSQHLSVRFETEE-ADRG
FVSGIGTVLKRSPESREDPAHLS---DSSSSSSSIVSFKSADSIKSRPSAPRLEGDGGER
A-SPENRE-PGA----GRK-EEAVESIMRKYLQK-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------WYEAE---KVW--LIQQDGFTLAT---QLKPDVGTPELP
AGRVRVRRDEDGTVTEVDEDSVQR------------------------------------
------TNPPSLDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1233)

EDLATLISLNECSVINTLRQRFRARLPCTYAGPGLVLHAGETITP
SVSTFRIFSMRI----LGRRDNPP-PHICSLAHRAYRNLLMQRQDQAIIPLGHSGAGRTR
CCQSALEYLVGTAGSLDGRVS-VEKIQAMFTVLGAFGSVTTKHSSSSTRFSMVLSLDFSA
TGQVTAAHLQTLLLERARVAQQPEGESNFNIFPLLLAGLDVAERTMLHLHQVAESNSFGI
KPFTKPEDKQRASVAFSQLRAAMGTLGITTEEQAAVWRILAGIYHLGAAGACKAGR--EL
GRKQFLRFESASRAAEVLGCDVEELGTAVFKHHLRHILAQVTARGQAEE-------SPPA
EGWAMTGVE-CVEGMASGLYEELFAAVVSLINRYQRAAGPLL--ILIIKLGSFESASRAA
EVLGCDVEELGTAVFKHHLRHILAQVTARGQAEESPPGTRMLQPLDLPSGAQ------SP
GVPW-QPQVLL-GSPGAARRGLLWILDEEVLTPGSGDGSAFER-LCSYFATKAPDQ----
DGEGHLRRCEQTLHFEICHQLGTAPVRYDLTGWVSKAKFNLSAQNAIQVLQNSTVAALRE
LLRPRASAPPCCRALAGLEGRSQAALHRNSCLRKTFASSFAAVRKRSVCAQLKLQADALT
NLLRRCQLHFVHCLLAGMGGEGPVPRP--PA--------PP----ELDVVALRTQLEGTQ
LLDALRLHR---VGIPSHASALWLLLQWSSPWN--------THASGWTCTDHKHSPC--C
GERE-LCRRRSRGMSWVFLKPGVISRLEKQRDKLIAQKMTLLQAACKGFLSRQKFKRLKI
QRLAIRCIQKNLLVFQAVRHWPWWQLLGHVRPLLSVNLAEEQ-LRAKEEELAALRRKLEK
SEQACSELRQTTE-SLESKIIDLTTELSDERYKGDVTCQALDGERAERLRGTRELQELQS
KHDQVQKKLESVEKQLEEAQQLVQLREMKISGS-GGGKDWQVRFDCAQTEIVFLRKRLAQ
LEERLEAELGTRTELEQKATNARAACQAARDGAQRLRRRCQRLACELEDARVLAENQQSR
SHELEKRQKKFDLQLAQALGQSAFEKSLREKLSQENTSIRWEMGK---LQQSLEHKEAEV
ARLEQQVAVLAGRVQELSAPG-ATD--TVPALKKKLWELEGSAAEQKKELERQTAAVDHL
EQAHERLELEIERMKQIHQKELEDKDEELEDMQKSCQKRLRQLEMQLEQEHEQKQMVLHE
KQDLEGLIGTLCEQVRGQSSMGYKRWRFCVLQQGKTLCGSGNK--RGCVARGQAPSACGF
CSFNDDPLEESEAKCAEAQRCQQTAALELENLHTELETLSRNKTLLQTQVEDVKKEKQSL
QEKRRMEEMKADMDELVQRELEKVIFSATDIAQIRELQTQVEDVKKEKQNLQE---KLQA
AQARAAQLEQCPAERSIVSRQEARIR-LESQLDFQAVQMKRFEVLVLRLRDSIIQMGEEL
EKAAESEARERENTRYYQRRMEEMKADMDELVQRELESSRRRMELEQQ-LAELAEVRQVL
QADLGTSIRRIADLQVALEGLRDSDDSED-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

------------------------------------------------------------
-------------------------------------IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKESQRKKQAALSPLPAQEXXXXXXXXXXXXXXX-XXXX-XXXX
X-XXXXXXXXXXXXXXXXXXXX-XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXX-------XXXXXXXX
XXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXX-X
XXPQTIGLKWA-----REELKSQPQVPGPG-EGG------------------------QS
GAEEKETEPPNKMENGGPSKNAVGEGQ--------QAGPHSQVRKWGGSLGRKAKWNDPQ
SKKDNEGELPRKEEKAGEPHLKTEK--------------------MEKAPGMEG-----P
LMVTEKMGEAQT--------------------------------------------KVEE
VGQPQSQ--------------PGEVG-GPQGKSDVACAAPEQGVTR----AASTVADRRE
DLPTNRGQKGEGPDPRADAMA---KVLEVELQGLGS-ALEAPVDQP--QTPENQERPALQ
EGDPGGHSGD---SDQVLADRWYEAE---KVW--LVQKAGFTLAT---VLKPDEGTADKP
PGRVRLCVDADKAIXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------
------XX------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXV
PSA-----C-----------RYVL-VPLASLAQRPSW

PF00063 // ENSGT00920000149027_1_Domain_1 (938, 1069)

SMLTQRIDQSIAALGGSGAGKTS
CSKQTLEHLAGVALTVDNTVS-VEKIRATFTVLQAFGSVSTGHSHSATRFAMVMSLDFNA
AGRITGAQLQTMLLEKSRVARRPEGEGNFKVFSQLLAGLALDLRTELY

ENSGT00920000149027_1_Linker_1_0 (1069, 1096)

LHQMADSNSFGM
GMWSKPEDKQKEALA

PF00063 // ENSGT00920000149027_1_Domain_0 (1096, 1127)

FAQLQGAMETLGILEQEQQAIWRVLAAIYHLGAAGACK------V
GRKQFMHFEWANRAAEVLGCEYEELNRATFKHHLQQIIEQVKAGSSRRG---LEDEETSS
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXGVPMPFDLPEPSPGATVAVVD
QNPSQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX---
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAVEALL
QTLDLEKEAVAVGHSQVFLKAGVVSRLEKQRERLV

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

SQSIILFQAACRGFLSRQEFRKCKI
LRLATRCIQRNVAVFLQVQDWPWWRLLGSLRPLLSTTLGEEQ-LRAKEEELTALRQKLEK
SERTRNELRQNAD-LLDSKIADLTTELADERFKGDVACQALEVERAERLRTFREVQELKX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXLGELQSAYEGAKKMVHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDMQLAQALGESVFEKGIREKVTRENTSIQWELGK---LQQQLEQKERDT
LQLKQEVERLQAHKQELLGAP-SVGQNGVADLKEKLWKMESHAVEQQKTQTQQENTIKQL
EQLRQQFELEIERMKQIHQKDREDQEEELEDMRQSSQKRLRQLEMQLEQEYEEKQVVLXX
XXXXXXXXXXXXXXIGHRDFDVEKRLRRDLKRTHALLSDVQLLLRAMEDTKTSVS--KEE
LEKVHRQLQQSEVKCEDALKTQKALTADLESMHSELENMSRSKNLVDEQLYRLQFERADL
L--KRIDEDQDDLNELMKKHKDLIAQSAADIGQIQEMQLQLEEANKEKHKLQEQ--XXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLVIRLRDSLMKMGEEL
AWAAASESRQRESSQYYQRRLEELKADMEELAQREVEASRRCLKLEKY-VEELSAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDVESVQTTLDCGG-----HKEMDNTSTFSSQPE
STLRSWMSCTL--SLATDTMRSPSRQSVISSRT---LGPRM--K-NKEAGDAERGQGTSA
PT----------------------------------------------------------
---------------------GACCPLGSWSASSASLQKHHHFGDGEGF-----------
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XX--XXXXXXXXXXXXXXXXXXX
XX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXASSDEGDLSLRPR-VQVPPEPEGT
-----AGLMRSS-SRCVSDSATAT-TPPLSERAKTRFSSCESLIESGSSS---LRDRSSS
-DPSRDTLVSPTLGPRRPFLDSSLDDASPAD--LGQKPLVFQNSQFAHLMAGPPGQDPPN
WKLPGLHYQPKTKADFDDFLPAIRKPEAPSPLSRA-TKDGQEHSQLSSVHFETED-ADCS
F----STALPKGLSPREEQAQLS---DSSSSSGSLLSFKSGDSVKSRPRALRLEGDGGER
T-SPDNRE-PGA----RRK-EDDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKESCIREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRRKAAAFTAPEVEIPAVTTNQTNK--TNN-VPKP-ESQQ
TSQDSSSTTQNSTDIPGKEPPG-AGDKDST--PVTSTSGERPQESGPTGTPAKRTLPFKR
GVRRGDVLLMVAKLDPELAKAEQKVQLHDVP------MDKTPTPA-------KDSGGTKK
GVTTGTSSAPQPS---M------SEKTRTRGVGDTGQ----STKGGKC---QGTEGKG-S
RDPQTNRQKEGES-QSTEEQGTRSQAQEAG-NKEQ-----------------------LG
TAKKEGGGPPKKMVKEDGPKVAGAEVR--------PVEPPVPLRKWGGFLGRRSKWDSPQ
SKDR-ITESHHKDEKTGDLQNP-----------AVDRSCGQLAEPTGQPSGPTGQPSDS-
---------------------------TEQPAGPTGQPAGPTGQQQ-----EAPVKMEGK
VGKPQKKL---VTPRKPREL-PGVAA--KTQNPEESCKAPDRIPTTG----ISAEAAKRD
GQPESRVQGAGEPHVCTEEEV---DMVKPQAEGHVEFVPEVGTERL-STLRPMEEKQILQ
DPDRGGQSGD-SDQA-Y-EDRWYEAQ---KVW--LVQKDGFMLAT---VLKPDEGTADPP
AGRVRLCIDADRTVIEVDEEQVHP------------------------------------
------ANPSELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1603)

EDLASLVSVNESSVMNTLLQRYRARLPHTCSGPDLIALQPQTTTV
PSS-----GKVP----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKLRATFTVLRAFGCVSTGHSRRATRFAMVMSLDFNA
TGRVTAAQLQTVLLENSRVARQPQGEGNFEVFSQLLAGLDVDLRTELNLHQMAESSAFGM
GLWSKPEDKQKAAAAFSQLRGAMELLGISEGEQQAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCDYEELNTATFKHHLRQIIEQMTSGLQRQG---LQ-DNETC
SGLKMTGVE-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDTPGFQNPRHQG
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YKEEGIPVPFDLPESSPGTTVAVVD
QNPS-QVHLPA-GRGAEDAGGLFWVLDEEVRVEGSSDNAVLER-LRAAFEKKK-EAGA--
EEPPSMRTCEQPLQCELFHQLGRDPVRYDLTGWLRRAKPNLAALEAPQILQQSKREELQS
LFQARAKLPPVCQAVAGLEGTSQQALHRSRVVRRAFASSLAAVKRKAPCAQIKLQMDALI
SLLRRSRLHFIHCLVPTTV-ESKAGQRTPSPSQPSGDQGVANESTALDIPALRVQLAGSH
ILEALRLHR---AGYAEHMG----LAQFRRRFQVLDPALLKKLDLTSEELDERK------
----------------VFLKAGVVSRLERQREKLVSRNIVLFQAACRGFLSRQEYKKLKI
RRLAALCIQKNLAVFLKVKDWPWWGLLASLRPLLSSTLGTEQ-LRAKEEELTLLRQKLQK
LENSRSELRQNAD-LLESKITDLTSELADERFKGDVACQALESERAERLQALREVQELKT
KYQQVQNALGEVQKQLEEAQQKIQGANLEEKPA-GGADEWQMRLDCAQMENDFLRKRLQQ
CEERLDSEMKARTELEQKLGELQNAYEEAKKMAYQLKRKCHHLTWDLEDTRVLLENQQSR
NHELEKRQKKFDLQLAQALGESMFEKSLREKVSQENNGVRWELGQ---LQQQLEQKEQEA
SKLKQEVERLQGQKRELLSCA-SGGDQGVASLKERVWELETNALEQEKIHSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQVALHE
KHDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATIEDSKTSIS--KEE
LEKVHSQLELSEAKCEDALKTQKVLTADLENMHSELENVTRSKSLVDEQLYRLQFERADL
L--KRIDEDQGDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLRE---QLHM
AQLRIQYLEQSTVERAIVSRQEAIICDLENKTEFQKVQIKRFEVLVIRLRDSIIKMGEEL
SRAVKAEAQQRENSQYYQQRLEELKAEMQELAQREEEASRRCMELEKY-VEELATVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDTESIQTAVDCSS---RSGKEGDNVSVISSQPE
GSLQSWMSCSL--SLATDSVRIPSRQSVVSNSF---HSPRV----SEEAGDSERLRT---
------------------------------------------------------------
--ASS--ALSGAWDAARDASKASSDSL-----HPVFPQKPYHLGNGEGF-----------
-AVHRKST--LEHSGP-LSSSPPSQRTAVSPPS-RDKLPSPSAALSEFVEELRRKRAQRG
QG-------STLHLGDGPVLPIFQTTRASSLRR-GRASSDEGDLSLKTR-VKSPLGAEGI
PGA-TAGLSRSTSLKCISSEGPED-ITLLPDKQKTHFGSCESLLESGPCT---RRKLSSP
T-----GLLSPTLRPRRPCLESSVDDAISLE--LGKEPLVFQNRQFSHLVEETLDSDPFS
WKLPSLNYRRQTKVDFDDFLPAIRKSDTPSSGA---AKDGKEASKHPGVHFEMGEAADRS
FLSGIKTILKKSPEVKEDPAHLS---DSSSSSSSIVSFKSTGGTGSGPRVPRLQGDGGER
M-SPEHRD-PGS----ARR-DDDVESIMRKYLQQ-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALASPEPEIPEISISQPNS-KSSS-GTRS-GSQQ
ISQDDQSSSPGSSDILGKKSEG-SRSPDPE--QMTSINGEKAQELGSSATPTKKTVPFKR
GVRRGDVLLMVAKLDPDSAKPEK-THPHDTP------PCKSPPPA-------TDTGKEKK
GENSRTPCGSQAS---TEILAPKAEKTRTGGLGDPGQGTVALKKGEEG---QSIVGKG-L
GTPKTTELKEAEP-QGKDRQGTRPQAQGPG-EGVQ-----------------------PG
KAEKEGAEPTNTVEKGNVSKDVGSEGK--------HVRPQIPGRKWGGFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----M---------------EKTSQVQGE---LGDDL
RM-GEKAGELQSMT-----------GKAGESWV-----------------------KKEK
MGQPQGK--------------SGNAG-EARSQTEKGCEVPKEVSTMV----ESPAAPGKG
GWPGSRGQEAEEPCSRAGDGA---GALETELEGPSQPALEKDVERP-RIQKENQDGPAPQ
EEGKGGQSRD-S--DQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKTITEVDEEHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1521)

VEDLASLISVNESSVLNTLLQRYKAQLPHTCTGPDLIVLQPRGPSA
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGVAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWG---LE-DEETS
SGLKMTGVD-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYTHERLQLLFYQRTFVSTLQR-YQEEGVPVPFDLPDPSPGATVAVVD
QNPS-QVRLPA-GGGAQDARGLFWVLDEEVRVEGSSDSVVLKR-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVPNPVVESRSGQESPTPPQPGRDKPGAGGPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTDLADERFKGDVACHVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQQVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSATSSCI---LSPRI----NEEAGDTERTQS---
------------------------------------------------------------
--AL---ALSRARSTDVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKST---ERLEP-ASSRLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRHMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSQRSSIHFETEE-ANRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDGGER
T-SPERRE-PGT----GRK-EDDVASIMKKYLQK-

------------------------------------------------------------
----------------MVSPASSLGSLLACLCKQ---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARLRKEAVLCPAVP-----GGHQPNS-KAHS-GTKS-GSQQ
TSGDSQSTSPQSTSIPGKDSQG-SGSADPA--LTTSINGERPQEPAPRGTPARKALPFKK
GVRRGDVLLMVAKLDPEAAKPEQRTQARDVP------TCKTSPTV-------TDPGGSKK
GETPGTPSGLQ-------DLASKPEKTPTGGHGDPGQ----GKKGEKG---QGTVAKG-S
GGPMTKGSKGGET-KGKEEQRTRPQSHGAG-DEGQ-----------------------LG
TVEKEGGDPPSKMEKIN--------DVG---AEGKRAGPQVQWRKWGGSLSRKSKWDGPQ
SKKDRESEPPSTTGKTGKPQAKM--------------------EEKGKGQGKAGQVGEVP
RTLEEAVELGKASE--------------------------------------A--LKSEE
VQQPKGKA---A----------G-T-GGAGTQAEKGCKTPKEVAAER----VSPVATEPE
RQPESSAQRAEEHCTKAEETA---GAPEPRQEGCGEPSRETQAEKP-PGQMQTQEGPGLV
GSNLRPPPRKQTLMGEALSSLFFHIP---SPLPHCFFLFPLQPAT---VLKPDEGTADLP
AGRVRLCIDADKTVTEVDEEHVHR------------------------------------
------ANPPELDQADDLASLISVNESSVLNTLLQRARAQLLHTCAGPDLLVLQPQGPAK
LSS-----GKVS----KGRRDGLP-AHISSLAQRAYWAMLSQRRDQSIIALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTILRAFGSACTGHSCSATRLAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARPPEGEGTFPVFSQML------------------------
-----PEDKQKA

PF00063 // ENSGT00920000149027_1_Domain_1 (1093, 1640)

ATAFAQLQGAMETLGITESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPSRRD---LN-DEEPS
SGFKMTGTE-CVEGMASGLYQELFAAVVSLINRSFSSHHLAMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYVHERLQLLFYQRTFVSVLER-YQEMAF-IFCGMPESSPHSTPGIHF
--LT-LVHLSA-GGGTEDAKGLFWVLDEEVRTEGSQDSVVLER-LRAAFEKTGEGAE---
SRISALRTCEQPLQCEIFHQLGQDPVRYDLTGWLHKAKPNLSALDAPQVLQQSKREELRS
LFQSRAKLPPVCQAVAGLEGTSQQALHRNRVVKRTFASGLASARRRAPCSQIKLQMDALI
SLVRRSQLHFIHCLVPTPAVDNKGGQGALPPPFA-GDQLGAGKPLAADIPALRVQLAGSH
ILEALRLHR---IGYADHMG----LTQFRRRFQVLDPVLLKKLVSAPEDTDERKAVEELL
QTLDLEKKVVAMGHSQVFLKAGVVSRLEKQREKLVSQNIILFQAVCKGFLSRQEFKKLKI
RRLATQCIQKNVAAFLAVKDWPWWQLFTSLQPLLSATVGNEQ-LRAKEVSPCC-RQTVRA
PENSTANRRQAPKLLQTLTIADLTTELADERFKGDVTCQVLENEHAERLKASREIQELRV
KSWKVLLSVL-------------LCAHAASYLC-DTADEWQMRLDCAQMENEFLRKRLQQ
CEERLDSELTSRKELEQKVRGRKQPRKG---NIHATL----------------------K
SCDMCSVLDRFDMQLAQALGESVFERSLREKMSQESNSVQWELGR---VQEQLE--EQET
LRLKQEVEMLQKHKRELLESP-SLGESGMADLKERLWKLESSAREHEKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KRDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDSKTSVS--KEE
LEKVHSQVDGR-LKCPFWL----------E------EWSSRLESVVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQVKIL-G---------------LLSVCP---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRLEALVIRLRDSLIKMGEEL
SRAVASESQQRESSQYYQRRLEELKVDMEELAQREAEASRRCMELEKY-AEELGAVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDSESVQTAVDCSS---GGRKEMDNVSVISSQPE
SSLQSWLSCTL--SLATDTVRTPSRQSAASSCI---RSSR--------------------
------------------------------------------------------------
MNGEAGDAESRSWNV--HSKTSRDNSV---SPCSTHQQKSCHLGDGEGL-----------
-GVQRKPM---ERSRA-LSSPVASQTPDTSPPP-REKLPSPSAALSEFVEGLRKKRAQRG
QG-------PTLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGDLSLKLQ-AKSPLGVEGA
SG-TSSGLSRSTSLKCISSGGAES-MSLPPERPKTRFSSCEALLESGPSV---RKKMSSP
TT-PRSILLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPCS
WTLPSLSYGRRARVDFDDFLPAIRKSETPTPLAGV-AKHGHEGSKHSGVHFEMEE-TDRS
FLSGIKTILKKSTESKEDPAHLS---DSSSSSSSIVSFKSADSVKSRPRPPRLEGDGGEQ
M-SPEPRE-LGA----GRK-EDDVESIMKKYLQK-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MDPV--LMTSINGEKPQESGPSGTPAKKSLPFRR
GVRRGDVLLMVAKLDPDSAKSEQRTQSRDAP------PRKTPPPA-------TDPGGGKK
GETPGTPHGPQAS---TEDASPKAEKTQTEGLRDLGT--VPLTKGEKD-----EVGKG-G
GAPQTQGVKGGEP-QGKEGPG----------EGGQ-----------------------PG
TVEKAGGDLSNKVAKGNLSKDAAGEGK--------WAGAQTQVRKWGASLGRRSKWEGPQ
SRKDKEGVLSQADKTHGL-Q-----SKA---------------EKAGAVQGKGGKLGEAP
RA-VEKAGERQSLT-----------GKAGEPQG-----------------------EVGK
VGQAQSE--------------SGEAG-KARSKTEKGSKAPKEVDAHE----QPRAATGKE
DKAGSREQEAEGTCTRAGDGA---RALGVEPEGPRQPGLESPAGRQ-QGQEES-PAERLQ
EASRGGQSAV-L--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADRSITEVDEDHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1517)

EDLASLVSVNESSVLNTLLHRYRAQLPHTYAGPDLIVLQPQGPTA
PSS-----GKVP----RGRRDGLP-AHIGSLAQRAYWALLSQRRDQSIVTLGRSGAGKTT
CCEQILEHLVGLAGSVDGRVS-VEKIRATFTVLRAFGSVSTGHSRGATRFAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARQPEGEGNFEVFSQMLAGLDLDLRTELYLNQMADSSSFGM
GTWSKPEDKQRAAAAFAQLQGAMETLGISESEQRAIWRVLVAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTAGPSRRG---PE-DEETS
SGLKMTGVE-CVEGMASGLYQEVFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLER-YREEGVPVPFDLPETSPGTTVAVVD
QSPS-QVHLPA-REGAEDTRGLFWVLDEEVRVEGSSDAVVLGR-LCASFEKKGAGA----
EETSALRSCEQPLQCEIAHQLGHDPVRYDLTGWLHRAKPNLSALDAPQVLLQSKREELRG
LFQARAKLSPVCRAIAGLEGTSQQAQQRSCAVRRTFASSFAAVKRKAPCSQIKLQMDALI
SVIRRSQLHFIHCLVPSPAVESRGGQGSPTPPQPGGDKPGAGGSPPLDIPALRVQLAGSY
ILEALRLHR---AGYADHMG----LTQFRRRFQALDPLLTKKLMSAPEGVDERKAVAELL
QTLDLEKRAVAVGHSQVFLKAGVISRLEKQREKLVSHSMILFQAACKGFLSRQEFKKLKI
HRLAACCIQRNMAVFLAVKDWPWWQLFGSLRPLLSATIGEEQ-LHAKEEELITLRQKLEK
SEKSRNELRQNAD-LLESKIAALTTELADERFKGDMACQVLESERAERLRASREVQELKS
KYEQVQKSLGEVEKQLEEAQQKIQLNDLERNHTGGGGDEWQLRFDCAQMENEFLRKRLQQ
SEERLDSELTSRKELEQKLGELQRAYDGAKTAAQQLKRKCLRLTCDLEDTRFLLESQQSR
NRELERKQKKFDAQLAQALGESVFEKGLRERLAQENTSVRCELGS---LQQHLKQKEQET
LQLKQEVEMLQAHKQELLASP-SLGENGIAGLKERLWKLESSALEREKIQNQQENTIKQL
EQLRQRFELEIERMKQLHQKDREDKEEELEDVRQSCQKRLHQLEMQLEQEYEEKQLVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDSKTSVS--KEE
LEKVQSQLEQSEAKCEDALKTQKALTADLESMHSELESMTRSKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAQKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQVATAESQQRENSQYYQRRLEELKADMEELVQREAEASRRCVELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGG---SGRKEIDNVSILSSQPE
GSLQSWLSCTL--SLATDTARTPSRQSAISSRI---LSPRM----HKEAGDAERAQR---
------------------------------------------------------------
--AS---PRS--GARDVHGRTSGDKAA---SPLSLRRGKPCHFGDGEEC-----------
-GVQTKPP---GRAGT-PSSSLASQSRDASPLS-RDKLPSPSAALSEFVEGLRRKRAQRG
QG-------SPLGLEDWPTLPIYQTTGASTLRR-ARAGSDEGALSLRS-GAPSPLGAEGA
AG-TSAGLLRSTSLKCISSESAGG-PTPLPEKLKTRFSSCESLLEPGAGA---RRKSSSP
SA-LRDSFLSPTLRPRRRCLESSLDDAGCPD--LGKEPLVFQNRQFAHLMGDPLDSDPFS
WKLPSLNYERKTKVDFDDFLPAIRKPETPTSLAGA-AKDGRDSSQHSSVHFETEE-ADRG
FLSGITTILKKSPELKEDPAHFS---DSSSSSSSIVSFKSADSIKSRPRIPRVEGDGGEQ
T-SLENRE-LGA----RRK-DEDVESIMKKYLQK-

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MR--------------QQDGSPG-----PAETPGVGQTQPEEGTALQ
EDSRGGQSGD-S--DQAPEDRWYQAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCLDADQTVTEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1637)

EDLASLVSVNESSVLNTLLHRYRAQLPHTCSGPDLIVLQPQGPWA
PPA-----AKVP----RGRRDGLP-AHVCSLAQRAYWELLSQRRDHSIVALGRSGAGKTT
CCEQVLEHLVAMAGSVDGRVS-VEKIRAAFMVLRAFGSVSTSHSRSATRFSMVMSLDFNA
MGRITAAQLQTMLLEKSRVARQPDGEGNFKVFSQMLAGLDLDLRTELNLHQTAESSTFGM
GVWSKPEDKQKAGAAFAQLRGAMETLGISESEQRAIWRVLAAIYHLGVAGACK------V
GRKQFMRFEWANHAAAALGCEFEELNTATFKHHLRQIIEQVTSRPRPRG---LE-EEEAS
PGLKMTGVE-CVEGMAGGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAQERLQLLFHQRTFESTLER-LREEGVPVKFDLPESSPATTVAVVD
QKPS-QVHLPA-GGGAEDARGLLWVLDEEVRVEGSSDSVVLER-LRVAFEK-GAGG----
EGTSALRTCEQPLQCEIAHQLGQDPVRYDLTGWLHKAKPNLSALDAPQVLQHSKREELQS
LFQARAKLPPVCRAVAGLEGTSEQASLRSRVVRRTFASSLGAVRRRAPCSHVKLQMDALV
NLVKRSRLHFIHCLTPTPTVESRGGQGSPTPPQPGGDQ-----PLSLDIPALRVQLAGSH
ILEALRLHR---TGYADHMG----LAQFRRRFQALDPALLKKLLSTSEGMDERKAVEQLL
MTLDLEKTAVALGHSQVSGASF--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-----------------------------------

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRRKQAVLTSPEPEAPEISNGQPIS-KSNS-STKS-GSQQ
ISQSSQSSSPQDSNIPSKESEE-ARSTDSL--LMTSINGEKPQGPSPSGAPAKKPLPFKR
GVRRGDVLLMVAKLDPDSTKLEQKTHPHDSL------ACKTPPPP-------TDPGGVKK
GGTAVAPCGPQAS---PEDPPLKAEKTHIGDIRNPGQGNVLLSKGEKG---LVSVGKG-D
RAPQTKEPKGTEP-QGKGSQGTRPG------EGER-----------------------LE
TVEKVREDPPNKMEKGSLSRDAGDKGR--------QVGAQIQVRKWGGSLSRRNKWGDSQ
NKKDKEGEPLSKVEKTGEPQIK-----M---------------EKTGKVQGKVEKVGGLL
SM-MEKAGKPQDMT-----------EKAGEPKT-----------------------EPEK
VGQPQSK--------------SLEAG-EARSKTETAGKASKEVDTPW----EAPAVAGEE
DQLGRRAQKTEEPCQRADTGA---EALELQLAGPGP-ELENHAESP-QTWEESQEGPALQ
EGGTGGQSRD-S--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDEDKTITEVDEECVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1518)

EDLATLVSVNESSVLHTLLHRYRAQLPHTCTGPDLIVLQPHGPST
PSA-----GKVP----RGRWDGLP-AHIGSLAQRAYRAMLSQRRDQSIVALGRSGAGKTA
CCEQVLEHLVGLAGSVDGRIS-VEKIRAAFTILRAFGSMSTGHSRSATRFAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARRPEGEGNFEVFSQLLAGLDLDLRTELYLHQMADNSSFGM
GVWSKPEQRMQSVEAHRPPQGLVVSLGYCGSKSSAMWDDLGQAFHLAVNFPCA------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPCRRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVISLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAQERLQLLFYQRTFASVLEQ-YQEEGVPVQFDLPESSPGATVAVMD
QNPS-QVRLPA-GGGVEDARGLFWVLDEEVRVEGSRDNVVLER-LCVAFEKKGAGA----
EETSPLRMCEQPLQCEVSHQLGRDPVRYDLTGWLRGAKPNLAALDAPQLLQQSKREELRS
LFQPRANLSPVCRAVAGLEGTSQQALQRICAVRRTFASSLAAVKRKAVCTQIKLQMDALT
GMIRRSKLYFIHCLVPN

ENSGT00920000149027_1_Linker_1_3 (1518, 1552)

PVVESRGERESPTPSQPGGDKLGTAEPLHLHIPA

PF00063 // ENSGT00920000149027_1_Domain_3 (1552, 1640)

LRVQLAGSL
ILEALRLHR---AGYADHMG----LSQFRRRFQVLDPPLMKKLMLVSDRIDERKAVEELL
QSLDLEKKAVAMGHSQVFLKAGVVSRLEKQREKLVSQSIILFQATCKGFLSRQEFKKLKI
RHLAAQCIQKNVAVFLAVKDWPWWQLLGSLRSLLSATIGDEQ-LRAKEEELTILRQKLEK
SEKTRNELRQNAD-LLESKIADLTTELAEERFKGDVACRVLESERAERLQAFREVQELKS
KYEEVQKKLGEVEKQLEEARQKIQLNDLRS-HT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTSRKELEQKLKELQSAYEGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDMQLAQALGESVFEKGLREKVSLENTSIRCELGK---LQQQVKQKEQET
LQLKQEVEMLQAHKQELLRSP-SLEQNGVAGLKERLWQLESSALEQQKIQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDIRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTTDLENMHSELENMTRSKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKNKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAIICDLESKTEFQRVQIKRFEVLVLRLRDSMIKLGEEL
SRAAASESQQRENSQYYQRRLEELKVDMEELVQREAEASRRCVDLEKY-VEELAAVRQTL
QTDLETSIKRIADLQAALEEVASS-DSDTESVQTAVDCGG---SGRKEMDNASILSSQPE
SNLQSWLSCTL--SLATDTVRSPSRQSVSSSHI---LSPRH--RMNKEAGDAVRTRP---
------------------------------------------------------------
--VS---ALSGG--QDVHSAPSGNKSVSS----SPRLQKHRHFGDGEGF-----------
-GTQRKPT---ERPGA-LSPSSSLRGGDASPLP-GEKLPSPSAALSEFVEGLRRKRAQRG
QG-------SALGLEDWPTLPIYQTTGASALRR-GRAGSDDGDLSLRSG-ARPPQEAEGT
PG-TPAGLVRTTSLKCISSDSLEA-TTPPPEKRKTRFSSCESLLESRPSV---GRRLSSL
AA-PRDLLLSPPLQPRRRCLESSLDDAGCPD--LGKEPLVFQNRQFAHLMEEPRGSDPLS
WKLPGLNYXR----------------------------DAQDSSQHSSIHFKTEE-ADRT
FLSGVKTILKKSPEPKEDPAHLS---DSSSSSSSIVSLKSADSIKSRPRLPRLEGDG-KR
T-SPGDRE-PEA----R-E-KDDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK-----EKDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALASPERETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-VGSPDPE--RMTSINGEKAQELGSSATPAKKTLPFKR
GMRRGDVLLMVAKLDLDSAKPER-THPHDTP------PCKTPPPA-------TDTGKEKK
GETSGAPCGPQAS---TEILVPKAEKTWTGGLGDTGQGTVALKKGEKG---QSIVGKG-G
GTPKTKELKEAEP-QGKDRQGTRPQAQGPG-EGVR-----------------------PG
KAEKEGGEPTSPVEKENISKNVGSEGK--------HVGPQIPGRKWGSFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----T---------------EKKNQMQGE---LGDEL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAEQPCSREDVGS---GALETELEGPSQPALEKDAERP-RIQKENQDGLAPQ
EAGKGGQSRN-S--EQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1520)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSVVALGRSGAGKTA
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADNSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPEPSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVLVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRNRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVLNPVVESRSEQESPIPPQPGRDKPGAGAPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLVSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIRRMWLWSSQSTDWPWWHPCVPFRALLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLNLELTARKELEQKLGELRSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQEVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSAVEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGTVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGKKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTVRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----LSRAWSADVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKST---ERSEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TA-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSQRSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKQKQIREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARLRKEAGLASPEQETPEISTSQPKS-NSSS-TTKS-GHQQ
ICQSNQSSSPQNSNIPGKESEG-AGPTDPV--LMTSINGEKPQESGPSGTPAKKPLPFKR
GVRRGDVLLMVAKLDLDSAKPEQRTQPHDTP------ACKAPPPA-------TDPGGEKK
GGTPGTPRGLQAS---TKDTAPKAEKTQTEGVGDPGT--VLPT----K---LDAGGKG-G
GAPQTKGLKGGEL-QSREGPG----------EGGR-----------------------QE
TAEKGGGDPPNKMAKGNLSKD-AGEGK--------WAGVQFQVRKWGGSLGRRSKWDGPQ
SKKDKEGTLPSKAEKSEETQVK-----A---------------EKVSKGQGKPGQVGEAP
GQ-VERTREPPSVP-----------GKAAEPQA-----------------------KLGK
EGQPQGE--------------SGEAG-KAGGKTEKGCKAPEEVGARR----ESPATAGKE
RCPESRRQEAGEPRTGADDGA---GVLEMELEGPRPPALESQAERP-QARKESEVGPPLP
EGSKGGQTED-S--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKSVTEVDEEHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

AEDLASLVSVNESSVLNTLLLRYREQLPHTFKGPDLIVLQPPGPPA
PSA-----GKVP----PGRRDGLP-AHPGSLAQRAYWALLSQRRDQSIVALGRSGSGKTT
CCEQVLEHLVAMAGSMDGRVS-VEKIRATFTVLRAFGSVSTGHSCNATRVAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARQPEGEGNFEVFSQMLAGLDLDLRTELHLHQLADSSSFGM
GVWPKPEDKQKAAAAFAQLRCALETLGISEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQMTSGPSRRR---LE-EEETS
SGLKMTGVE-CVEGMASGLYQELFAALVSLINRSFSSHHLSMASIMVVDPPGFQNPRHQW
KDRAATFEELCHNYAHERLQLLCYQRTFASTLER-YRQEGIPMPFDLPEPSPGTTVAVVD
QNPS-QVRLPA-VGGAEDARGLFWLLDEEVRVEGSSDGMVLER-LCTAFEKKGAGT----
EGTSALRSCEQPLQFEIFHQLGQDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQPRAKLPPVCRAVAGLEGTSQQALQRSCAVRRAFASSFAAVKRKAPCSQIKLQMDALT
SVIRRSQLHFIHCLVLGPAVESRGGQGSLIPPQPGGNKPGTGGPLPLDIPALRVQLAGSH
ILEALRLHR---TGYADHLG----LAQFRRRFQVLDPLLMKKLMLASEGVDERKAVEELL
QTLNLEEKAVIVGHSQVFL

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KAGVVSRLERQREKLA

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

SHRILLFQAACKGFLSRQEFRKLKI
RQLAAQCIQKNMAAFLAVKDWSWWQLLGSLRPLLSTTIGDEQ-LHAKEEELTMLRQKLER
SEKSRSELRQNAD-LLESKIADLTTELADEHFKGDVACQVLERERAERLRAFREAQELKS
KYEQVQKNLGEVQKQLEEAQQKIQLSDLERSHT-AGADEWQMRFDCAQMENEFLRKRLQQ
FEERLDSELTSRKELEQKLGELQSAYEGAKKLAHKLKTKCHRLTCDLEDTRLQLENQESR
NHELEKKQTKFDMQLAQALGESVFEKGLREKVTQENTSIRWELGQ---LQQQLKQKEQET
SQLKQEVETLQAHKRELLGSS-SLGENCVAGLKERLWKLESSALEQQKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGSMEESKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTTDLENMHSELENMTRSKSLVDEQLYRLQLERADL
L--KHIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHSLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
TQAVKSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDTESVQTAVDCSS----GRKEIDNISVLSSQPE
GSLQSWLSCSL--SLATDTMRTPSRQSASSSHI---LSSRM----NDEARDAEMSQP---
------------------------------------------------------------
--AS---ALSRA--RTAQSQTSGDKSV---SPLCLRRQKYYHLGDGDEC-----------
-SGQRKPT---ERLGA-RSPSPASRSADTSPVS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------SPLGLEDWPTLPIYQTTGASTLRR-ARAGSDERHLSLGFGTKSAL-EPEGA
SG-MSSGLLRSTSLKCLSPQSAES-TTPLPERRKTRFSSCESLFESGQSS---GRKLSSP
SS-SRSMLLSPTLRPRRRCLESSLDDTGCPD--LGKEPLVFQNRQFARLMEEPLDSDPFT
WRVPSLHYERKTKVDFDDFLPAIRKPESPVSLARA-AKEGQDTSQHSRIHFETEE-ADRT
FLSGVKTILKKSPESKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPRIPRLEGDGGER
T-SPEHRE-PGA----GSK-DEDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKESDIREENKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRTKEAALASPERETPDVSSSS----MTNS-DPQA-RSQR
ISPASPFPSPQSTDIPGRESPV-ASGKDSA----LVASGEKTREQSPSVTPAKKPAPFRR
GVRRGDVLLMVAKLDPELAKPEQRTL-----------TGKPLAPA-------SDPGGTKK
GDTPGTPRGPQDS---N------ADRARTGGAEDPGQ----DTKGEKQ---QGTAEKG-S
QGPQTKGKRAGEPPEGKGEQGTRSQAQGPG-DKGK-----------------------VK
TAEEGGSLPKKK----------KDVPQE---AEGRLTEPPVPVRKWGGPLGRRSKWDSPQ
SKKDKVTEPPKRAEKAGEQQTKMKERGQ--------------------------------
------------------------------------------GQVP-----ESPGKKMEP
AGEART---------------------------SQEEKAPE------------RVAARKE
GRPESSARDSGEPRLQTGGGG---GTPGLQPEGLAEPAPRTEVERPAAQR---PVVGTEE
EPGRGGQSGD-S--DQALEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDEDKTVTEVDEDSVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1234)

EDLASLVSVNESSVLNTLLHRFKAQLPYTHTGPDLILLQAS----
--G-----GKVP----RGQQDGPP-AHIVSLAQRAYWALLSQRRDQSIVALGRSGSGKTV
CCEQVLEHLVGMAGSVDGRVS-VEKIQATFTILRAFGCVSTSRSPTATRFAMVMSLDFSA
TGRVTAAQLQTMLLEKTRVARQPEGEGNFQVFSQLLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGITEGERRAIWQVLAAIYHLGAAGACK------V
GRKQFMRFERATHAAEALGCNYEELNTATFKHHLRQIIQQMTAGPRR-S---PG-DEDTP
SGLKMTGAE-CVEGMASGLYQELFAAVVSLINR

ENSGT00920000149027_1_Linker_1_3 (1234, 1547)

DS--HHFQPHSA----HPGNQ------
-----------------------------HVPSV-IFQEGVPVNFDLPESSPGATVDVVD
QNPS-QVHSTA-GGDTGDARGLFWVLDEEARMEGSSASTVLEC-LRAAFEKKGAGA----
EGTPVLRACEQPLQCEIAHQLGQDAVRYDLSGWLPRAKPNLSALEAPHILQQSKREELRS
LFQPRANLPPVCRAVAGLEGTSQQAVHRSRVVRRTFASSLAAVKRKAPCVQIKLQMDALV
NLVRRSQLHFVHCLMPISAVEIKGGQGTPSPPCPGRNQQGADETPA

PF00063 // ENSGT00920000149027_1_Domain_3 (1547, 1640)

LDIPALRVQLAGSH
ILEALRLHR---AGYADHMG----LAQFRRRFQALDPVLLKEFASTSEGVDERKAVEQLL
QALDLEKKAVAVGHSHVFLKAGVVSRLERQREKLVSGNIVLFQATCRGFLSRQEFKKMKI
RQLAARCIQKNMAAFLAVKDWSWWQLLTSLRPLLTAAIGTEQ-VRAKEEELTLLRQKLQT
SEKLRSELRQSTD-LLESKIADLTSELADERFKGDVACQALENERAERLQAFREVQDLKS
KYEQVQRKLGDVEKQLEEAQHKVQLPDMEKKPT-GGADEWQMQLDCAQLENEFLRKRLQQ
FEERLESELASRKELEQKFGELQSAYEEAKKMAQQMKKKCHHLTWDLEDTRVLLENQQSH
AHELEKKQKRFDMQLAQALGESLFERKLREKASQETVSVRWELSR---LQQQLEQKEQET
STLKQEIERLQDHKRELLGS---AGDNCVAGLKEKLWKLESSAREQEKVHSQQENTIKQL
EQLRQRFELEIERMKQMRQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLTTVDEGKTSVN--KEE
LEKVHSQLEQSKAKCEDALKTQKALTADLESMHSELENMTRSKSLVDEQLHRLQFERTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQIQLEEAKKEKQKLQE---QLQV
AQLRIEYLEKSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SRAAMSEAQQRENSQYYQRRLAEMKVEMEELVQREAEASRRCMELEKC-MEELVAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGI---RGRKETDNVSVVSSQPE
GSVQSWLSCSL--SLATDTARSPSRQSAISSSL---LGPRT----SQDNRDAER--P---
------------------------------------------------------------
--A---SSLSRAWDVPSKASR-----VDSASPQSIHLQKPYHFEDGEGF-----------
-ALQRKPTV--ERSGVLLSSSPTSRSTDMSPPP-REKLPSPSAALSEFVEGLRKKRGQRG
QG-------STLRLEDAPTLPIYQTTGAFALRR-GRTSSDEGDLSLRLG-TKSPLEAEGG
PG-TAAGLLRSTSLKCITSEGAEG-ATPLPDKPKTRFSSCESLLESGLSS---GRNQSSL
AT-PRDPVLSPLLRPRRPCLESSVDDAVCPD--LGKEPLIFQNRQFAHLTGEPLDSDPLS
WKLPSLSYRRQTKVDFDDFLPAIRKPSAPGPSAGAAKDGPPEASKRSSVHFELEG-AGHS
FLSGVKTILKKSPGSKEDPAQLS---DSSSSSSSIVSFKSADSVKSAPRRPRLEGDGGER
T-SPGHRE-PGA----GQK-EDDVASIMKKYLQT-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MEIK------------E
----EQGEIKEEQR--------------EIKEKPVEI-----KEEPG-------------
---EIKEPGESTDSNKVHDDVWYETE---KVW--LVEKDGFTLAT---VLKPDVGTPELP
AGRLRIRIDADNTVTEVDEETLHR------------------------------------
------TNPSTLDC

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

TEDLAALISLNESSVIHTLQHRYWSQLCHTYAGPSLVAVKPSWAAT
SYS-----GKVF----RGKRDSMP-PHICSLAQKAYWSLLMRRQDQAIVPLGRSGAGKTT
CCQSTLEYLVGAARSVDNRVS-VEKIQAMFTILKAFGTVTTGHNSTSTRFSMAMSLDFNA
TGRITAAHLQTMLLERVRVTQQPEGESNFNVFSQMLAGLDMAHRTMLHLHQMAESNSFGI
RPCAKTEEKQKASAAFVQLQAAMETLGITADEQSAIWRVLAGIYHLGAAGACKATS--QI
GRKQFMKFEWANKAAEVLGCDYEELTTSVFKHHLKQIIEQVTSGT-SRPSKDQEQNAGYP
LGAKMTGVE-CVEGMASGLYEELFAALVSLINRSFSSSHLSMASIMVVDAPGFHNPRHQK
KERAATFEELCHNYVHERLQALFYKRTFVSELER-YREENVEVPCELPELSPMATVSVIE
QNSS-QLHVPP-GGQAEDPKGLLWILDEEVLIPGSSDSVVLDR-LCSYFAKKGAES----
EEEGVLRKCEQMLQCEIFHQLGKDPVRYDLTGWMNKAKLNLSAQNAIQVLQQSQIDALKK
LFLPRSKMLLICRSVAGLEGHSQQALQRTGCVRKTFASSFAAVKKRSVCAQIKLQMDALT
NLVKRSQIHFVHCLVPRAGVDGTDGKP--P----CLT---GEAELTLDVPTLRVQLSGAQ
LLDALRLYR---IGYADRMV----LTQFRHRFQVLAQPAMKKFTSAYEIPHENKAIEELF
KVLDLEKKSVAVGRSQVFLKPGVISRLEKQREKLISQNMILIQAACKGFLSRQKFKRLKI
QRIAVRCIQRNLAAFQVVKDWPWWQLMSWVRPLLRVNLVEDQ-LRVKDEELTALRRKLEK
SEQSCSELRQNTD-VLESKIT-LTKGVAQKTNVNEGACQVLEGERAERLRGAREIKELQS
KYDQVRKEFESVEKQLEETQQQIQLREIGLHGA-AGEEEWQMRFDCAQTEITFLRKRLAQ
LEERLGAELNSRKELEHKLCEVQNNYESVKKVAQQMKRKCKHLACDLEDTRVLTENLQSR
NHELVKKQKKFDMQLAQALGESAFEKSLREKVTQENTTIRWELGK---LQQMSEQKDLET
SNLNQRIALLATQVQELTSSE-TWDEGAVAALRKKLWELESNAAEQQNELSRHVTAAEQL
EQLHMRLEMEIERMKQMHQKDLEDKEEELEDVRQSCQRRLRQLEMQLEQESEEKQMVLHE
KQDLEGLIGTLCEQIGHRDFDVEKRLRRDLKRTHALLADVQLLLVTTGEPNSSVG--KEE
LEKIRSQWEESKAQYAEAQKSQKAMALELESLHVELETISRNKNLVEEQLYQLQHEKADL
L--KRIDEDQEDLNELMTKHKALIAQSAVDITQIRELQSQLEEVKKEKQSLQE---KLQV
ALTRIAYLEQSMVERSIVSRQEALICDLENKLEFQSVQVKRFEMLVLRLRDSVIKMGEEL
EKAAEPEAGEKENTKYYQMRMEEMKADMNELVQRELEASRRRVEL---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------EQ------PCSDMGKKTNLNEETLQEPFPRGSSIKKPLPFRR
GVRRGDVLLMVAKLDPDSAKLEQKTHPHDSL------TCKSPPPS-------TDPGGAKK
RGTPAAPGSPPAS---PEDLAQKAEETLTGGLRDSGQENVLLPKGEKG---QDSVGKG-V
RAPQTKELKGAEL-QGKERQGTRPQAQGSC-EGEQ-----------------------KE
TVEKVREDPQNKMEKGTLSKDAVDEGK--------QVGAQVQMKKWEGSLDRRSKWGDSQ
NKKDK-GEHLSKGEKTGEPEIKI--------------------EKTGKVQGKVGKVGGPP
SM-TERAGEPQRTT-----------EKAGEPKT-----------------------KIEK
VGQPQSKS--------------TE-VGEGWSETQNGCKAPKEEVA---TSGESPVAAEKE
DQLENRGQKAKEPCQRADNGAEAXXXXXXXXXXXXXXXXXXXXXXXXX---------XXX
XXXXX--XXX-X--X-XXXXXXXXXX---XXX--XXXXXXXXXXX---XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXX-------------------------
------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-----XX

PF00063 // ENSGT00920000149027_1_Domain_1 (911, 1725)

VP----RGRWDGMP-AHISSLAQRAYWAMLSQRRDQSIVALGRSGAGKTT
CCERVLEHLVGLAGSVDGRVS-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXTMLLEKSRVARQPEGEGNFEVFSQVLAGLDLDLXXXXXXXXXXXXXXXXR
GMWSKPEDKQRAAAAFAQLQGAMELLGISESEQRAIWRVLAAIYHLGVAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPSRRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVISLINRSFSSYHLSTASIMVVDSPGFQNPQHQG
KDRAATFEELCHNYAHERLQLLFYQRTFASTLEG-YREEDVPVQFDLPESSPGATVAVVD
QNPS-QVCVPA-GGGAKDARGLFWVLDEEVRVESSRDSVVLER-LCEAFEKKGIGA----
EETSPLRTCEQPLQCEIAHQLGQDPVRYDLTGWLRRAKPNLAALDAPQLLQQSKXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXYADHMG----LTQFRRRFQVLDPPLMKKLMLASEGINERKXXXXXX
XXXXXXXXXXXXXXXXVFLKAGVVSRLEKQREKLVSQSIILFQATCKGFLSRQEFKKLKI
RRLATQCIQKNMTVFLAVKDWPWWQLLGSLRPMLSATFGDEQ-FRAKEEELTMLRRKLEK
SEKSRNELRQKTG-LLESKIADLTTELTEERFKGDVACQALESERAEQLQAFREVQELKX
XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXDEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTSRKELEQKLRELQTAYEGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSR
NHELEKKQKKFDMQLAQALGESVFEKGLREKVSQENTNVRWELGK---LQQQVKQKEQET
LQLKQEVEMLQAHKQELLRSP-SLGQNGIAGLKERLWQLESSALEQLKIQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDIRQSCQKQLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGTMEDAKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTTDLENMHSELENMTRSKSLXXXXXXXXXXXXXXX
X--XXXXXXXXXXXXXXXXXXXXXXXSAADIGQIQELQLQLEEAKKEKNKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAIICDLENKTEFQRVQIKRFEVLVIRLRDSMIKMGEEL
SRAAASESQQRENSQYYQQRLEELKADMEELVQREAEASRRCMELXXXXXXXXXXXXXXX
XXXXX-XXXXXXXXXXXXXXXXXX-XXXXXXVQIAVDGGG---SGKKEXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX----XXXXXXXXXXXXX--
---------X--------XXXXXXXX---X---------------XXXX-----------
--XX---XXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXX-----------
-XXXXXXX---XXXXX-XXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXX-X-XX
XX--------XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXXX-X--X-XX-XXXXX
XX--XXXXXXXXXXXXXXXXXXXX-X---XXXXXXXXXXXXXXXXXXXXX---XXXXX--
XX----XXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX
WTHPSLSYKYKTKVDFDDFLPAIRKPNTSSSFTGA-SKDAQGSLQHSNLHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPRLPRLEGDGGEH
M-SPENRE-PGT----GRK-DDDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKE--IRDEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARQRKETALASPEREAPEIPFNQTNSTKS--------GSQQ
IS-----SSSQSADILGRKSEG-AGTVDPM--LMTSINGERPQESGPSGTPARKPLPFKR
GVRRGDVLLMVAKLDSDSARPEQRTQPRGAP------TCKTPPPA-------TDPGVEKK
GETSETPCGPQAS---TKDAAPKAERTQAGGLGDLGT--VLPTEGEKD---QGTVRKG-G
GAPQTKGVKGGEL-QGKEGPG----------EGGQ-----------------------PG
TVEKRGGDPSSKVAKGNLSQEAAGERK--------WAGVRTQVRRWGVSLGRRSMWDGPQ
SKNDKESVLLSANKTELXXXXXXXXXXXXXXXXXX--------XXXX------X-XXXXX
XX-XXXXXXXXXXX-------------XXX-XX-----------------------XXXX
XXXXXXX------------X-XXXXX-XXXXXXXXXXXXXXXXXXXX----XXXXXXXXX
XXX-XXXXX---XX--XXXXX---X--XXXXXXXX--XXX-XXXXX-XXX-X-XXXXXXX
XXXXXXXXXX-X--XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXTVLKPDEGTADLP
AGRVRLCIDADKSITEVDEDQLHRXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------
--------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX
XXX-----XXXX--------XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXGFSXXXXXXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXTM

PF00063 // ENSGT00920000149027_1_Domain_1 (1033, 1060)

LLEKSRVARQLEGEGSFEVFSQMLAGL

ENSGT00920000149027_1_Linker_1_0 (1060, 1093)

DLDLXXXXXXXXXXXXXXXXX
XXXXXSEDKQRA

PF00063 // ENSGT00920000149027_1_Domain_0 (1093, 1127)

AAAFAQLQGAMETLGILKSEQRAIWRVLAAIYHLGAAGACK------X
XXXXXXXXXXXXXXXXXXXXXXXXXNTATFKHHLRQIIEQVTSGPSRRS---PDDED-TS
SXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXENVPMSFDLPEPSPGATVDLVD
QSPS-QVRLLA-GGGAEDARGLFWVLDEEVRVEGSSDGVVLER-LRAAFEKKEAGAEXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXYADHMG----LTQFRRRFQVLDPLLMKKLLSAPEGINERKAVEELL
QTLDLEKKAVAVGHSQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXIAELTTELADERFKGDMACQVLESERAEWLRASREVQELKS
KYEQVQKSLREVEKHLEEAQQKIQLNDLERSRT-GGADEWQMRFDCAQMENEFLRKRLQQ
SEERLDSELASRKELEQKLGELQTAYEGAKKMAHQLKRKCRHLTCDLEDTRFLLESQQSR
NHELEKKQKXXXXXXXXXXXXXXXXXXXXXXXXXXNTSVRCELGR---LQQCLEXXXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXXXXVARLKERLWKES--SAEQEKIQNQQENTIKQQ
EQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGRTSIS--KEE
LEKVQSQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDEQLHRLQFERADL
L--RRMDEDQDDLNDLMQKHKDLIAQXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEKY-V-EEAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDRGSG---GAKEXXXXXXXXXXXX
XXXXXXXXXXX----XXXXXXXXXXXXXXXXXX---XXXXX--XLQEEAGDAERTQRAS-
------------------------------------------------------------
-------ALG--GARDFRSQTSGDKVV---SPLSLRRRKYAHSGDGEEC-----------
-GVQRKPPERSGALSSSPSSSPSSRSRDTSPLS-RDKLPSPSAALSEFVEGLRTPSS---
------------------------------------------------------------
-----------------------------------------------P------------
-SAPRDSFLSPTLRPRRRCLESSLDDAGCLD--LGKEPLVFQNRQFAHLMEDPLGSDPFS
WKVPSLNYERKTKVNFDDFLPAIRKPEMRTSLARV-ARDGQDSSQHSSVHFETEE-ADRG
VLSGITTILKKSPESREDPAHLS---DSSSSSSSIVSFKSVDSIKSRPRVPRLEGDGGER
T-SPETRE-LGA----GRK-DEDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKESGIREEDKSPPPSSPPPLFSIIPGG
FIKQLVR----ETEKESKEARRRKEAAFTSPEVETPAVPTNQINK--TNN-VPKP-GSQQ
TSQDSSSTTQNSADIPGKEPPE-AGDKDST--PVTSTSGERPQES---GTPAKRTLPFKR
GVRRGDVLLMVAKLDPELAKAEQKVQPRDVP------VDKTPAPP-------KDSGGTKK
GVTTGTSSAPQPS---M------PGKIRIRGVGDTGQ----STKGGKC---QGTEGKG-S
QNPQTTGQKEGES-QSTEEQGTRSQAQEAG-NTGQ-----------------------LG
TAEKEGGGPPKKMEKEDGPKVAGAEVR--------PVDPPVPLRKWGGFLGRRSKWDSPQ
SKNR-VTESHCKDEKTGDLQSP-----------AVDRSCGQPAGPTGQPTGP--------
-------------TGQPAGPTGQPAGPTGQPAGLKGQPAEPKGQQQ-----EAPVKTEGK
VGRPQKKL---VTPKKPREL-PGVAA--KTQNPEGSCKAPDRIPTTG----ISAEAAKGD
GQPESRVQGAGEPRVHTEEEV---DVVKPQAEGNLESVAEISMERL-STQRPMEEKKILQ
DPDRGGQSGD-SDQA-Y-EDRWYEAQ---KVW--LVQKDGFTLAT---VLKPDEGTADPP
AGRVRLCIDADRTVTEVDEEQVHP------------------------------------
------ANPSELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLISVNESSVLNTLLHRYRAQLPHTCSGPDLIALQPQMTTV
PSS-----GKVL----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQALVHLVGMAGSVDGRVS-VEKLRATFTILRAFGCVSTGHSRRATRFAMVMSLDFNA
TGRVTAAQLQTVLLENSRVARQPQGEGNFEVFSQLLAGLDVDLRTELNLHQMAESNAFGM
GLWTKPEDKQKAAMAFSRLRSAMELLGISEGEQQAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEVLGCDYEELNTATFKHHLRQIIEQMTSGPQRQG---LQ-DNETC
SGLKMTGVE-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDTPGFQNPRHQG
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YKEEGIPVPFDLPESSPGTTVAVVD
QNPS-QVHLPA-GRGAEDAGGLFWVLDEEVRVEGSSDSTVLER-LRASFEKKKEEAGA--
EEPPSMRTCEQPLQCELFHQLGRDPVRYDLTGWLRRAKPNLAALEAPQILQQSKREELQS
LFQTRAKLPPVCRAVAGLEGTSQQALHRSRVVRRAFASSLAAVKRKAPCAQIKLQMDALI
SLLRRSRLHFIHCLVPTTV-ESKAGQRTPSPSQTSGDQGVANEPTALDIPALRVQLAGSH
ILEALRLHR---AGYSEHMG----LAQFRRRFQVLDPALLKKVDLTSEELDERKAVEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSRNIVLFQATCRGFLSRQEYKKLKI
RRMAALCIQKNLTVFLKVKGWPWWRLLVSLQPLLSSTLGTEQ-LRAKEEELTLLRQKLQK
SENSRSELRQSTD-LLESKITDLTSELADERFKGDVACQALESERAERLQALREVQELKT
KHQQVQDALGEVQKQLEEAQQRIQVANLEEKPA-GGADEWQMRLDCAQMENVFLRKRLQQ
CEERLDSEMKARTELEQKLGELQTAYEEAKKMAHQLKRKCHHLTWDLEDTRVLLENQQSR
NHELEKRQKKFDLQLAQALGESMFEKSLREKVSQENSGVRWELGQ---LQQQLEQKEQEA
GKLKQEVERLQGQKRELLSCA-SVGDQGVASLKERVWELETKALEQEKIHSQQEENIKQL
QQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQVALHE
KHDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATIEDSKTSIS--KEE
LEKVHSQLEQSEAKCEDALKTQKVLTADLENMHSELENMTRSKSLVDEQLYRLQFERADL
L--KRIDEDQGDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLRE---QLQV
AQLHIQYLEQSTVERAIVSRQEAIICDLENKTEFQKVQIKRFEVLVIRLRDSMIKMGEEL
SRAIKAESQQRENSQYYQQRLEELKAEMQELAQREEEASRRCMELEKY-VEELATVRQTL
QTDLETSIRRIADLQAALEEVGSS-DSDTESVQTAVDCSS---RSGKDGDNVSVISSQPE
GSLRSWMSCSL--SLATDSVRIPSQQSVVSSSF---HSPRL----SEEAGDSERLRT---
------------------------------------------------------------
--ASS--ALSGTWGAPRDASKAGSASL-----HPVCPQKPYHLGDGEGF-----------
-AVHRRST--LERSGS-LSSSPPSQSTAVSPSS-RDKLPSPSAALSEFVEELRRKRAQRG
QG-------STLHLGDGPVLPIFQTTRASSLRR-GRASSDEGDLSLKTR-GKSPLGAEGI
PGA-TAGLSRSTSLKCISSEGTED-ITLLPDKQKTRFGSCESLLESGPCT---RRKLSSP
T-----GLLSPTLRPRRPCLESSVDDAISLE--LGKEPLIFQNRQFSHLMEETLDSDPFN
WKLPSLNYRRQTKVDFDDFLPAIRKNDAPSSGA---AKDGKEASKHPGVHFEMGEAADRS
FLSGIKTILKKSPEAKEDPAHLS---DSSSSSSSIVSFKSTGSIGSGPRVPRLQGDGGEQ
M-SPEHRD-PGS----ARRGDDDVESIMRKYLQQ-

MNSGGRRRQGHGEGSSSYCFSPELLFPCRPGVSVSGLGPPISCTVRGCEAHSVLPAGGTT
LPHRLIDNRLVSPPHAPALPSMAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKQARQRKEAALASPEQETPEVSVSQPNS-KANG-GDTS-GSQQ
TSGESQRTSLQGTSIPGKESQQ-SGGADPA--LMTSVNCERPREPGPSGTPARKALPFKR
GVRRGDVLLMVAKLDPEATKPEQRNQARDTP------TCKTLPAA-------TDPGGAKK
GEAPGTSSGPQAS---TEDLASKPEKTPTRGHGDPGQ----GTKGEKG---QGTVGKG-S
GDPQTKGPKGGEP-KGKEEQRTGPQSQGAG-DGGQ-----------------------LG
TVEKEGGDPPSKMGKRNES-----KAVG---AEGKRAGAHVQGRKWGGSLSRRSKWDGPQ
SKTDRESEPLSMAEKTGKPQAKM--------------------EERGTVQGKAGQAGEVP
QVLEEAAGPGKARE--------------------------------------A--PRSEE
VGQPQRKA---V----------G-T-GGAGSQAEKGCTIPKEVATER----VEPVAVEPE
GRPESSAQRTEEPCIRAEDAA---RGPEPQQEGHAEASVETWAERP-PGQTQTQEGPAQQ
DQGGGGHS---GDLDQAHEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRMRLCIDADKTVTEVEEEYVHR------------------------------------
------ANPPELDRA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

DDLASLISVNESSVLNTLLQRAEAQLLHTCAGRDLIVLQPQGPTA
PSA-----GKVP----SGRRDGLP-AHISSLAQRAYWAMLSQRRDQSIIALGRSGAGKTT
CCEQVLEHLVGMAGSVDGMVS-VEKIWATFTILRAFGSVCMGHSCRATRLTMVMSLDFNA
TGRVTAAQLQTMLLEKSRVVRPLKGEGTFPIFSQMLAGLDLDLRTELYLYQMADSSSFGM
GVWSKPEDKQKDAAAFAQLQGAMETLGITEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANRAAEVLGCEYEELNTATFKHHLRQIIEQVTSGPSRRG---LK-DEEPS
PGFKMTGTD-CVEGMASGLYQELFAAVVSLINRSFSSQHLSTASILVVDSPGFQNPRHQG
KDRAATFEELCRNYVHERLQLLFYQRTFVSVLDR-YQEEGIPVHWDLPESSPGTTVAVVD
QNPS-QVHLPT-GGDTEDARGLFWVLDEEVRVEGSHDSTVLER-LRAAFEKNGAGAK---
-GTSALRTCEQPLQCEIFHQLGQDPVRYDLTGWLHRAKPNLSALGAPQILQQSKREELRS
LFQGCARLLPVCQAVAGLEGTSQQALHRNRVVRKAFASSLASARRRTPCSQVKLQMDALI
SLVRRSQMHFIHCLVPTPALDDKGGQWSSPPPLP-GDRPEASKPLAPDIPALRVQLAGSH
ILEALRLQR---MGYADHMG----LTQFRRRFQVLDPTLMKKLTSAPEGVDERKAVEHLL
QTLDLEKKAVAVGHSQVFLKAAVVSRLEKQREKLVSRNIVVFQAVCRGFLSRQEFRKLKI
RRLAAQCIQKNVAVFLVVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTVLRQKLEK
SEKSRNELRQSAD-LLESKVADLTTELADERFKGDAACQVLEDERAERRQASREVRELRD
KYEQVQKNLGEVERQLVEAQQKIQLNDLERKHT-GGADEWQMRLDCAQMENEFLRKRLQQ
CEERLDLELKSRQELEQKLGELQSAYEEAKKTAHQLKRKCHRLTWDLEDTRVLLESQQSR
NHELEKKQRKFDLQLAQALGESVFERSLREKASQESSSVRWELGR---LQEQLEQKDQET
LRLKQEVETLQEHKRELLASP-SLGESGVAGLKERLWKLESSAREHEKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEARQMVLHE
KRDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDGKTSVS--KEE
LEKVHGQLEQSKAKCEDALKTQKALTLDLESMHSELENMTRSKSLVDEQLYRLQFERADL
L--KRIDEDQDDLDDLMQKHKDLIAQSAADIGQIQELQLRLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQMKRLEVLVIRLRDSLIKVGEEL
SQAAASEAQQRESSQYYQQRLEELKADMEELMQREAEASRRCVELEKY-VEELGVVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDPESVQTSVDCGS---GGRKETDDVSVLGSRPE
GSLQSWLSCTL--SVATDTVRTPSRQSAAGSCI---RSSR--------------------
------------------------------------------------------------
MTAEAGDAESRARDA--PGKTSRDYSV---SPRSAHQQKSCHLGGGEGF-----------
-GVHRKPM---ERSGA-LSTPVASRSPDASPLP-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------CTLSLEDWPTLPIYQTTGASMLRR-SRAGSDEGDLALRLQ-AKSPLGVEEA
PG-TSAGLLRSTSLKCISSGDVEG-RSPAPERLKTRFSSCESLLESEPSV---RTKTSSP
TT-PRDTLLSPTLRPRRRCLESSVDDVGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPCS
WTLPSLSYGRKARVDFDDFLPAIRKPETLPSLAGA-AKDGQEGSKHLGAHFEMEE-ADRS
FLSGIKTILKKSKESKEDPALLS---DSSSSSSSVVSFKSAHSIKSQPRAGRLEGDSGER
M-SPDSRE-LGT----GRT-EEDVESIMKKYLPK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRRKEAALASPEGETPEVPINQANK--TNN-VPKP-GGRK
TCQDSPSATQKDADIL-------ADDKNST--SVTSTGGEKPQESGPTGTPAKRTLPFKR
GVRRGDVLLMVAKLDPQLATPEQKTQPRDTP------KDKTPTPA-------TDPGGTKK
GANTGTPCGPQTP---I------TEKTRTGGDGDTSQ----GTKGGTC---QGTEGKG-S
GDSQTKAQKECES-QGTEGQETKSPAQGAG-NKGQ-----------------------VG
TAEKGGGGPPKKMGKGNGPKSAGAEVR--------PLEPPVPIRKWGVSLGRRSKWDSPQ
SKNR-ESESQCRDEKRGDLQGTA-------------------------------------
--------------------------------------AEPRGQQQ-----ETPGM-MEK
AEEPQKKL---VTPGKCQEQ-PGVAAAAETQSPQERCKAPGGTPTEATLAAQVAEAAKRE
DQPESRVQGAGEPCVHAEEEV---GIEEPRAEHHVESLPKTQEDRP-SLQKPTEEQPVRQ
DPGSGDQSRD-SDQA-SEEDRWYEAQ---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCMDADKTVTEVDEEQVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLVCVNESSILNTLLQRYGAQLPHTRSGPDLIALQPQKTRV
PSS-----GKVP----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSILALGRSGAGKTT
CCEQVLEHLVGMTGSVDSRVS-VEKLQAAFTALRAFGSVSTGHSRRATRFAMVTSLDFNA
TGRVTAAQFQTVLLENSRVARQPQGEGNFEVFSQLLAGLDVELRTELNLHQTLESNAFGM
GVWSRPEDKQKAATAFSQLRGAMELLGISEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCDYEELNTATFKHHLRQIIEQMTSGPQRQG---LE-DNDAS
SGLKMTGVE-CVEGMASGLYQELFGAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YQEEGIPVHFDLPESSPGTTVAVVD
QNPS-QAHLPA-GKATEDAGGLFCILDEEVRVEGSSDSVVLER-LHAAFEKKT--AGA--
DGPPVLRICEQPLQCELFHQLGQDPVRYDLTGWLRRAKPNLSALEAPQVLQQSKRKELQD
LFQARAKLPPLCRAVAGLEGTSQQALHRGRVVRRAFASSVAALKRKAPCAQIKLQMDALI
SLLSRSRLHFIHCLVPASV-ESKPGQGTPSPPQPGGDQGVANEPPALDIPSLRVQLAGSH
LLEALRLHR---AGYADHMG----LTQFRRRFQVLDPLLLKKLDSTSEGLEERKVVEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSRNIVLFQAACRGFLSRQECKKLKI
RRLATQCIQKNLAVFLEVKDWPWWGLLASLRPLLSPTLSVEQ-LQAKEEELTLLRQKLQK
SEKSRSELRQSTD-LLESKITDLTSELADERLKGDVACQALESERAERLQALREVQELKA
KYQQVQEALGAVQKQLEEAQQKIQLASFEEKHA-GGADEWQMRLDCAQMENDFLRKRLQQ
CEERLDSEMKARTEVEQKLGELQNAYEEAKKTAHQLKRKCHHLTWDLEDTHVLLENQQSR
NHELEKRQKKFDLQLAQALGESMFEKTLREKVSQENNGVRWELGQ---LQQQLEQKEQEA
SKLKQEVERLQGQKRELLGCA-SVGEQGVASLKERVWELESNALEQQKVHSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQVVLHE
KRDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKVLTTDLENMHSELENVTRSKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNGLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLRE---QLQV
TQLRIQYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQMKRFEVLVIRLRNSLIKMGEEL
SQAAKSEAQQRENSQYYQRRLEELKAEMQELVQREEEASRRCMELEKY-VEELAAVRQTL
QADLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---RSRKEEDNVSVISSQPE
GSLRSWMSCSL--SLATDTVRTPSRQSAVSSSL---LSPRA----SEEAGDAEKLRP---
------------------------------------------------------------
--ASL--ALTEDWDSPRETLRSGSVSL-----HPAFPQKPYHLGDGEGF-----------
-AVHKKDT--PEEPGT-LSSSPTSQSMAMSPLP-RDKLPSPSAALSEFVEELRRKRAQRG
QG-------SSLHLGEGPTLPIFQTTGAYSLRR-GRASSDEGDLSLRTG-AKSPLQAEGN
PRA-TAGLSRSTSLKCIPSEGTEN-ITLPPDKQKTRFGSCESLLESGPST---RRKLSSP
MA-LRDPLSSPTLRPRRRCLESSVDEAVCLD--LGKEPLVFQNRQFSHLMEETLDSDPFS
WKLPSLNYRRQTKVDFDDFLPAIRKPSAPLSEA---AKDGKEASKHPNVHFEMEE-ADRS
FLSGIKTILKKNPESKEDPAHLS---DSSSSSSSIVSFKSTGSIKSGPRVPRLQGDGGER
M-SPEHRE-PGP----GRKC-DDVESIMRKYLQQ-

------------------------------------------------------------
---------------------MAISSRLALWEQK-KQIREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEAKRKKQTLANSQEQTSPPMASSVPEN-SDSS-AQRSPQGSQ
SDPASPSPSAAVENIPN-EK---EGMASPEPVLMSSINGENPQGKGTVETTPRKPQPLKR
ARKTSDVLLMVAKLNSEFPKPEQRFPRTDSL------TPKPSSSIPDREGHVNPPADQQK
GQHSGDTRGPQEA---TEDSAEKAEKS--GTVGSPGSTSAPAKKSEKP---QIKAG-K-V
GVPVTKGLKGGEP-QSKEVLGTQPQAKGGEQGGEA-VVKVAKEDRAQMPQV-EGA-Q-PP
TNGEAGDQPQSKPGKAGLLKDAAGTGKEVQSKVGKGDRAHMQMKKWGESLNKWRKRSGSQ
SQVGKDSESSSQVKE-SEPQSQGAE-----------------------------------
------ERKPQNQTGKECGS---------------------QSQ----------------
VEQRDEK-------GTCVQSKEGKE-DDASQREEGGNEALKEG----KEVHEPPTTEKKE
GVPENKEET---------------------------------KETPEKT--------K-E
EEEEDGERDQTVVPNEELEDRWYEAE---KVW--LVQKEGFTLAT---VLKPDVGTPELA
AGRVRLCIDSDKSITEVDEESIHR------------------------------------
------ANPPELDLA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

ENLASLQSLNESSVLNTLGHRYRAQLLHTYTGPDLIVLQPPGVPA
PVS-----WKAP----RGRRDGLA-PHVCSLAQKAYWAMLSQRQDQALVPLGRSGSGKST
CCERALEFLVASAGSGNGRVS-VEKIRATFTILRAFGSVLTTHSSSSTRFSMVMSLDFNA
TGRVTAAHLQTMLMERIRVAQQPEGEGNFAVFSQMLAGLDLDTRTELYLHQMAENHSFGM
GVWAKPEEKQKAAAAFSHLQGAMETLGISAGEQQAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEVLGCEYEALTTAVFKHHLQQIIQQATSRLNQP-------HREFV
AGPKMTGVE-CVQGMAAGLYEELFTVIVSLINRSLASNDLSLFSIMVVDSPGFHNPRHQK
KERAATFEELCHNYVHERLQALFFRKKFEAEVER-YREEKVAVPFDLPEFSPRTTVAIID
QNLS-QVRVPV-AGQAEEPKGLLWVLDEEVQVEGSGDSAVMDR-LCLAFEKKEVGA----
DEAPAFRKCEHGLQFEISHQLGRDPVRYDLSGWIQKAKPNLSALNAIQVLQQSRREDLSS
LFLPRSRVPPICRAVAGMEGCSQQALHRVGCVRKTFASSLAAVKRKAVCAQIILQMDALT
NVIKRSQLHFIHCLVPGSGWEDRGGSASPAPAD---------REPPLDISILRVQLAGAQ
VLDALRLHR---IGYTDHMG----FTRFRRQFQGLAPAFMKKLLLPQERMEERKLIEELL
QELDLEKAAVQLGKTQVFLKSGVISRLERQREKLVSRNIILFQAACKGFLSRQQFKRLKI
RQLAVQCIQRNLKVFQEVKEWPWWQLLCYTRPLLSITIGEDQ-LRAKEEELTALRKKLET
SEKSRNELRQNAD-LLESKIADLTTELSDERFKGEVACRVLESERAERLRASREIQELKS
KYEQAQKSLGSVEKQLEEAQQKIELSQEGKPHS-GEAEDWQTRFDCAQTEIEFLRKRLLM
CEERLEAELSARKELEEKLGQARNSCEEAKRSSHQLKKKCRNLTCDLEDTRVLLENQQSR
NHELEKKQKKFDMQLTQAIGESLFERGLREKLSQENSGIRWELGK---LQSKLEEKEQET
LGLKQKLEMLRGHNLDLRPCTLPVGVENVADLQKELWDLKSSAFEQHKIQNEQETTIKKL
EQLRIRFEMEIERMKQMHLKDQEDKEEELEDVRQSCQKRLRQLEMQLEQENEEKKMVLHE
KQDLETLIGTLCEQIGHRDFDVEKRLRRDLRRTHALLSDVQLILSSIEDSQMTVS--KEE
LEKVHSRLQESEAKCADAQNTQKLLALDLENMHSELENITRNKNLVDEQLYRLQLERADL
L--KRIDEDQEDLNELMKKHKELIAQSSQDIVQIQELQLSLEEAKKEKQSLQEK--QLHV
ALSRIEHLEKTTVDRNIVCRQEALICDLENKLEFHKVQIKRFEVLVIRLRDSAIKMGEEL
EKAVSSETEQKESCLYYQRRMEEMRADMAELMKQEAETSRRCLDLEKR-VEELLAIRLTL
QADLEISIRRIADLQAALEEVDSC-PSDDSNEQTKVNANKY-----NQSLLDSCISSQPV
ESVRSWLSSS---SIRPSSTRSPSQQSASGSGI---LDQSF----NKKAGTLEKSTAPPP
----------------------------------------------SFL-----------
-------PLEREKERNVIQKDSDSVPV---STGVARHDKSCHSRDYGST-----------
-IGSENPE----TWRD-TVTKPKSRSSNTSPTL-EKKLPSSSWALSEFLEGFRKKQSDRE
RG--------ALGAEEWPTLPIYQTTGASSLRRSLETVTLP---------EKSSLETE--
TEGPRAGLLRSSSLKCLSSDRFDS-SLSLPAPPKSLYRSCESLLDSENAEGGFGRTLVPS
VGDSLGKFTQSKLRLRRPCIDTPLEEVEDPD--LGKESLVFQNRRFSNLLNEPLEPDLLA
WKLPK--YEQKPKVSFDDYVPAIRKPSSPTRAMDR-----GDDPKPGTSRYMSET-SPDC
LFLGSSGTFRKNLEPKEDTGHLS---DSSSSSSSAMSYRSADSIKSRPGSLKRDEESDRR
S---------GYGTWMDSNRQEEVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----GTEKEAKEARQRKQLAVASPEREIPEISISQPNS-KSSS-GTRS-GSQQ
ISQDDQSSSPGSSDILGKESEG-SRSPDPE--QMTSINGEKAQELGSSATPTKKTVPFKR
GVRRGDVLLMVAKLDPDSAKPEK-THPHDAP------PCKTSPPA-------TDTGKEKK
GETSRTPCGSQAS---TEILAPKAEKTRTGGLGDPGQGTVALKKGEEG---QSIVGKG-L
GTPKTTELKEAEP-QGKDRQGTRPQAQGPG-EGVR-----------------------PG
KAEKEGAEPTNTVEKGNVSKDVGSEGK--------HVRPQIPGRKWGGFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----M---------------EKTSQVQGE---LGDDL
RM-GEKAGELRSTT-----------GKAGESWD-----------------------KKEK
MGQPQGK--------------SGNAG-EARSQTEKGCEAPKEVSTMV----ESPAAPGKG
GWPGSRGQEAEEPCSRAGDGA---GALETELEGPSQPALEKDAERP-RIRKENQDGPAPQ
EEGKGGQSRD-S--DQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLWIDADKTITEVDEEHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1519)

VEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWG---LE-DEETS
SGLKMTGVD-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YQEEGVPVQFDLPDPSPGTTVAVVD
QNPSQQVRLPA-GGGAQDARGLFWVLDEEVHVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQQVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSATSSRI---LSPRI----NEEAGDTERTQS---
------------------------------------------------------------
--AL---ALSRARSTNVHSKTSGDKPV---SPHFVRRQKYCHFGDGEVL-----------
-AVQRKST---ERLEP-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKSKTQFSSCESLLESRPSM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS-AKGGQDGSQRSSIHFETEE-ANRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGER
T-SPERRE-PGT----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRRKEAALAPPEEETPEVPTTQANK--TNH-VPKP-GSRQ
TSQDSPSTTTKSADIPGKEPPG-ADDKNAAAASVTSTVGERPQESGPTGTPAKRTLPFKR
GVRRGDVLLMVAKLDPELAKPEQKTQPRDTP------MDKTPAPD-------TDPGGAKK
ETTTGTPCGPRAP---I------PEKTRTRGNGDTGQ----GTRGGKC---QGTEGKG-S
RDPQTKGQKECES-QSMEGQGTGSPAQGAG-NQGQ-----------------------EG
TAEKEGGGPPKKMEKGGAPKDAGAEVR--------PMEPPVPTRKWGGPLGPRSKWGSPQ
SKNR-ETEPRRRDEKMGDLQGT--------------------------------------
--------------------------------------AEPRGQQQ-----EAPGR-KEK
AGKPQKKP---VIPEKHQEQ-PGAAAETPE----ESREAP-------ATEETLADAARKE
DQPESRMRGAEEACVRVEEDV---DIVEPRAEGHVAPAPEIRVEKP-SMQKPVEEEPGLQ
DPGRRGQSGD-SDQA-L-EESWYEAQ---KVW--LVQKDGFTLAT---VLKPDEGTADLP
PGRVRLCIDADKTVTEVDEEQVHR------------------------------------
------ANPSELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLVSVNESSVLNTLLQRYRAQLPHTRSGPDLIAMQPQRTTV
PSA-----GKVL----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKLRAAFTVLRAFGSVSTGHSRRATRFAMVTSLDFNA
TGRVTAAQLQTMLLENSRVARQPQGEGNFEVFSQLLAGLDVDLRTELNLHQMAESHAFGM
GVWSQPEDKQKAAAAFSQLRGAMELLGITEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWASHAAEALGCDYEELNTATFKHHLRQIIEQMTSGPQRQS---LE-DNDTC
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YQEEGIPVHIDLPESSPGTTVAVVD
HNPS-QVHFPA-GRGAEDAGGLFWVLDEEVRVEGSSDSVVLER-LRAAFEKKV--AEV--
DGPPVLRTCEQPLQCELFHQLGRDPVRYDLTGWLRRAKPNLSALEAPQVLQQSQREELQN
LFQARARLPPVCRAVAGLEGTSQQALHRGRVVRRAFASNTAALKRKAPCAQIKLQMDALI
SLLSRSRLHFIHCLVPTSV-KSKTEQAPPSPPQPGGDQGGANESPALDIPALRVQLAGSH
ILEALRLHR---AGYAEHMG----LAQFRRRFQVLDPPLLKRLDLTSEGLDERKAVEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSRNIVLFQAACRGFLSRQECKKLKI
RKLATQCIQKNLAVFLEVKNWPWWGLLASLRPLLSPTLSMEQ-LRAKEEELTLLRQKLQK
SEKSRSELRQNTD-LLESKITDLTSELADERFKGDVACQALESERAERLQALREVQELKA
KYQQVQEALGEVQKQLEEAQQKSQLVNLEEKHE-GGADEWQMRLDCAQMENDFLRKRLQQ
CEERLDSEMKARTELEQKLGELQSAYEEAKKTAHQLKRKCHHLTWDLDDTRVLLENQQSR
NHELEKRQKKFDLQLAQALGELMFEKTLREKVNQENSGVRWELGQ---LQQQLEQKEQEA
SKLKQEVEKLQGQKQELLGCA-SVGEQGVASLKERVWELESNALEQEKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEEMEDVRQSCQKRLRQLEMQLEQEYEEKQVALHE
KRDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDGKTSVS--KEE
LEKVHSQLTQSEAKCEDALKTQKVLTADLENMHSELENVTRSKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNGLMHKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLRE---QLQV
AQLRIQYLEQSTVDRAIVSRQEAVICDLENQTEFQKVQMKRFEVLVIRLRNSLIKMGEEL
SQAAKSEAQQRENSQYYQRRLEELKAEMQELAQREEEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCSS---RSRKEEDNVSVISSQPE
GSLRSWMSCSL--SLATDTVRTPSRQSAVSSPL---LSPRV----SEESRDAEKLRP---
------------------------------------------------------------
--ASSASALSGAWDAPRQTSRAGSESL-----HPVFPQKPYHVGDGEGF-----------
-AVPRKTT--PERSGT-LSSSPPSQSMAVSPLP-RDKLPSPSAALSEFVEELRRKRAQRG
QG-------SSLHLGEGPTLPIFQTTGASSLRR-GRASSDEGDLSLRTG-AKSPLGAEGN
PRA-TAGLSRSTSLRCISSEGTEN-VALMPDKQKTRFGSCESLLESGPST---RRKLGSP
VA-PRDPLLSPTLRPRRRCLESPVDDAVCPD--LGKEPLIFQNRQFSHLMEETLDSDPFS
WKLPSLNYRRQTKVDFDDFLPAIRKLSAPLSEA---AKEGTEASKHPNVHFEMEE-ADRS
FLSGIKTILKKNPEPKEDPAHLS---DSSSSSSSIVSFRSTGSIKSGPRVPRLQGDGGER
M-SPEHRE-PDP----GRKG-DDVESIMRKYLQQ-

------------------------------------------------------------
------------------------ISLFVCFCKQ---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRRKEAVLASPEQETPEVSVNQSNS-KTNS-GTKS-GSQQ
TSGDSQSTSLQGTSIPGKDNQH-SGTADPA--LMTSVNGERHQEPGPGGIPARKALPFKK
TVRRGDVLLMVAKLDPEATKPEHRNQAHDTP------TCKTPPAA-------TDPGGAKE
GETPGT-SGPQAS---TEDLASKPEKTLTGGHGDPGQ----GMKGEKG---QGT------
------GPKGGEP-KDKEEQRTRPQSRGAG-DGGQ-----------------------LG
TVEKEGGDPPTKMEKRNES-----KDMG---AEGKHAGPRVQGKKWGEFLS-RSKWDGPQ
SKKDRESELPGMAEKTGKPQAKM--------------------EERGKVQGKAGQAGEAL
QTLGKAAEPGKASE--------------------------------------A--PKSEE
VGQPQRKA---A----------G-T-GRAGSQADKGCKVPKEVAIER----VSPAVTEPE
DRPESRAQRAEKPCTKVEDAA---GGPEPQQEGCAEPSLETRVEKP-PGQTQAQEGPTLQ
DQGRGGHS---GGLGQAHEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTVTEVDEEHVHR------------------------------------
------ANPPELDY

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

VDDLASLVSVNESSILNTLLQRARAQLLQTCAGPDLIVLQPQGSMA
PSS-----GKVP----RSRRDGLP-AHVSSLAQRAYWAMLSQRRDQSIIALGRSGAGKTT
CCEQVLEHLVGMAGCVDGRVS-VEKIQATFTILRAFGSVCTGHSCSATRLAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVVRPLEGEGNFPVFSQMLAGLDLDLRTELYLYQMADSSSFGM
GMWSKPEDKQKDVAAFAQLQGAMETLGITEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIAQVTTGPSRRG---LK-DEEPS
SGFKMTGTE-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYIHERLQLLFYQRTFISVLER-YQE----------------------
------VRLPT-GGRTEDARGLFWVLDEEVQAEGSEDSVVLER-LRTAFEKKGAGAK---
-GTSALRTCEQPLQCEIFHQLGQDPVRYDLTGWLHRAKPNFSALDAPQLLQQSKREELQS
LFQGRAKLPPVCQAVAGLEGTSQQALHRSRVVRRTFTSSLASTRRRAPCSQIKLQMDALI
SLVRRSQLHFIHCLVPTPALDNKGGQESSAPPLP-GDQQEASKPLAPDIPALRVQLVGSH
ILEALRLHR---TGYADHMG----LSQFRRCFQVLDPALLKKFMSVPEGIDERKAVEELL
ETLDLEKKVVAMGHSQVFLKAGVVSRLEKQREKLVSQNIILFQAVCRGFLSRQEFKKLKI
RRLAAQCIQKNVAMFLALKDWPWWQLLGSLRPLLSATVGNEQ-LRAK-------------
------------------EIADLTTELADERFKGDVACQVLENVCAERLQASREVQELRN
KYEQVQKNLGEVERQLEEAQQKIQLNDLERKHT-GGADEWQMRLDCAQMENEFLRKRLQQ
SEERLDSELTSRKELEQKLGELQSAYEEAKKTAHQLKRKSHRLTWDLEDTRVLLETQQSQ
NHELEKKQKKFDMQLAQALGESVFERSLREKAIQESSSMRWELGQ---LQEQLEQKEQET
LRLKQEVEMLQKHKQELLASP-SLGASGVASLKERLWKLESSAQEHEKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGSLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLVTVDDGKTSVS--KEE
LEKVHSQLKQSEAKCEDALKTQKALTLDLESMHSELENMTRSKSLVDEQLYRLQFERADL
L--KHIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRLEVLVIRLRDSLIKMGEEL
SQAVASESQQRESSQYYQRRLEELKVDMEELLQREAEASRRCMELEKY-VEELGAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDT------------------ERDNVSIISSQPD
GNLQSWLSCTL--SMATDTMRTPSRQSATSSCI---RSSRA--ELMEYNGETEVLGQVQN
QVGGRQGPWRSEQVDKGTVKINFKGAGGRWKGGSQHRNRKCKLQKQYSLILTQEQQSNVK
MNAEAGDAESRTWDA--HGKTSRDYSV---SPCSTRQRKSCHFGGCEEF-----------
-GVQRKPM---ERSGA-LSTREASRSPDTSPLP-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------SSLGLEDWPTLPIYQTTSTSRLRR-GRAGSDEGDLSLRLQ-AKSPLGEEGS
PG-TPAGLLRSTSLKCISLGVAEG-TSLAPERLKTRFSSCESLLESEPSV---RRKTSSP
TT-PRNTLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPCS
WMLPSLSYGRKARVDFDDFLPAIRKPEMPTSLAGA-AKDGHEGSKHSGVLFETEE-ADRS
FLSGIKTILKKSAESREDPAHLS---DSSSSSSSIVSFKSAGSIKSQPRSPRLEVSGGER
M-SAENRE-SGT----GRK-DDDVESIMKKYLPK-

------------------------------------------------------------
---------------------MAISSRLALWEQK-----EKDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALASPERETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-VGSPDPE--RMTSINGEKAQELGSSATPAKKTLPFKR
GMRRGDVLLMVAKLDPDSAKPER-THPHDTQ------PCKTPPPA-------TDTGKEKK
GETSGAPCGPQAS---TEILAPKAEKTRTGGLGDTGQGTVALKKGEKG---QSIVGKG-G
GTPKTKELKEAEP-QGKDRQGTRPQAQGPG-EGVR-----------------------PG
KAEKEGGETTSPVEKENISKNVGSEGK--------HVGPQIPGRKWGSFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----T---------------EKKNQMQGE---LGDNL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAERPCSREDVAS---GALETELEGPSQPALEKDAERP-RIQKENQDGLAPQ
EAGKGGQSRN-S--EQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1434)

EDLASLISINESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQGRDQSVVALGRSGAGKTA
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GAWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPEPSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVHVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKSIKK--
---------------------------------------------SSPC-----SLDALT
SMIKRSRLHFIHCLVLNPVVESRSEQESPTPPQPGRDKPGAGAPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLNLELTARKELEQKLGELRSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQEVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSAVEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDKQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGTVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGKKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTVRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----LSRAWSADVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKST---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TA-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSQRSSVHFETKE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MKGRDPEVSQGQESTGRE
GQPHPAVAKGEEP-RKESEPGDRPLRSA--------------------------------
-------------GMRDEAQIRAEKGAEPQKGAEKGSKSQVQVIKWGQSCAKVGKMDEPS
AKAGGETGPQAKSGGETGSRAK--------------------------------------
---TGGEAGPQAKTGVEAGPRSETGGEAGPQAKIE---------------------KETE
FGWRNGS---------QKDL----ESESRGQTRRPGWEEPSHGMSTG-------------
GEAQSKEADGNEPQT-------------TAAGGPE----------P-QTDKESGGEPATV
LEQEDGEQGRDDDSDQESEDRWYETE---KVW--LVQKDGFVLAT---VTKPDVGTPELA
AGRVRLRLEADDSITEVDEENVQR------------------------------------
------ANPAEYDLA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1060)

DNLAALTSLNESSVLNTLRHRYGARLTHTFAGPDLIALQPGGAGD
PDA-----MKVP----RGRRAGLPPPHVCSLAQGAYWAMLGQRRDQAIVPLGRSGSGKTA
TCQQALEHLVGFAGSVDGRLS-AEKIRAMFTVLRAFGSVSGGHPGGSTRFSMIASLDFGA
SGRVAAAHLQTLLLESVRVAQQPEGESNFLVFSQMLAGLDLDLR----------------
------------------------------------------------------------
------------------------------------------------------------
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-----------------------------------

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARLRKEAALASPEREIPEVSAGQPSA-G-----TKP-GS--
--QNAQSGPPPSADVLGRKDEE-AGTKDPV--LM-TINGEKPQESGPSGTPAKKSLPFKR
GVRRGDVLLMVAKLDPDSAKPEQRTQPRDAP------TSKTPPPA-------TDPGGGKK
GDTPGTSRGPQAS---TTDTPPKAEKTQTGGLGDP--GTVLPMKGEQD---QGTVGKG-G
EAPQTKGVKRGEL-Q---------GKEGLG-DGGQ-----------------------PG
TEEKGAGDPPNKGAKGSLSKDVAGEGK--------WAGAQAPVRRWGSSLGRRGKWDSPQ
RKKDKEGPLLSKADKTEEPQTK-----V---------------EKTGKVP---GKAGEAP
RA-VDKAGEPQSRT-----------GKAGEPRG-----------------------KMEK
VGPPQSA--------------SEEVS-KAEGKAEKDDKAPKEVDARG----DTPTTAGKE
DQPESRGQKAEEPRPRAGKGAG---ALEMEPGGPGQPALDT----------------ESQ
EGHGGGQSRV-S--EQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCVDADGSVTEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1519)

EDLASLVSVNESSVLNTLLHRYQAQLPHTLAGPDLIFLQPQGLMA
PSA-----GKVP----RNRRDGLP-AHISSLAQRAYWALLSQRRDQSIVTLGRSGAGKTT
CCEQVLEHLVGMAGSVDGSVS-VEKIRAAFTVLRAFGSVSTGHSRSATRCAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARQPEGEGNFEVFSQMLAGLDLDLRTDLYLHQMADSNSFGM
GLWPKPEDKQRAAAAFAQLQGAMETLGISDGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWASHAAEALGCEYEELNTATFKHHLRQIIAQVTSGPSRRS---LE-DEEAG
SGLKMTGVE-CVEGMASGLYQEVFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQS
KDRAATFEELCHNYAHERLQLLFYQRTFVLALQR-FREEDVPVQFDLPESSPGTTVAVVD
QTPS-QVRLPA-GGGAEDARGLFWILDEEVRVEGSQDSVVLER-LCAASEKHGAGA----
EGASALRTCEQPLQCEIAHQLGHDPVRYDLTGWLHRAKPNLSALDAPQVLQHSNREELRT
LFQSRAKLSPVCRAVAGLEGTSQQAQQRSCVVRRTFASSLAAVKRKAPCSQIKLQMDALI
SVIRRSELHFIHCLVPST

ENSGT00920000149027_1_Linker_1_3 (1519, 1547)

AVESRGGQGSPTPPQPGGDKPEAGRSLP

PF00063 // ENSGT00920000149027_1_Domain_3 (1547, 1640)

LDIPALRVQLAGSC
ILEALRLHR---TGYADHMG----LTQFRRRFQVLDPVLAKELISAPEGVDERKAVAQLL
QTLDLEKKAVAVGHSQVFLKAGVVSRLEKQREKLVSQSIILFQAACRGFLSRQGFKKLKI
HRLAARCIQKNVAVFLTVRDWPWWRLLGSLRPLLSATIGEEQ-LRTKEAELTALRQKLEK
SEKSRNELRMNAD-LLESKIAELTTELADERFKGDVACQVLETERAERLRASREVQELKS
KYEQVQKNLGEVEKRLEEAQQKIQLNDLERSHT-GGADEWQMRLDCAQMENEFLRKRLQQ
SEERLESELASRNELEQKLAELQRAYEGAQRTAQQLKRRCHLLTCDLEDTRFLLENQQSR
NHDLEKKQKKFDAQLAQALGECVFEKGLREKVAQENTSVQCELGK---LQQLLKQKEQER
LQLKQEVEMLQAQKQELLRSP-SLGENCIAGLKERLWKLESSALEHEKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDKEEELEDVRQSCQRRLRQLEMQLEQEYEEKQMALHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGAMEDGKTSVS--KEE
LEKVQSQLEQSEAKCEDALKTQKALTADLENMHSELESMTRSKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKNKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAAAAESQQRENSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAIRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVNCGGG--SSRKEIDDVSTLSSQPG
ASLQSWLSCTL--SLATDTARTPSRQSAVSSRT---LSPRT----HEEAGD---------
------------------------------------------------------------
------------GARDVRSRTSGDKAA---SPLSRRRGTYGHFGDGEEC-----------
-GVQRKTP---ERPGA-PP-SPSSRSGDASPLP-RDKLPSPSAALSEFVEGLRRQRAQRG
RG-------SPLGLEDWPTLPIYQTTGASTLRR-ARAGSDEGALALRAG-AGS------A
LD-ASAGLPRSTSLKCISSQSVGS-PSPPPEKLKTRFSSCESLLESGPSS---QRTPPSP
AAARRDPLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMGDPLGSDPFS
WKVPSLNYERKTKVDFDDFLPAIRKPETPTSLARG-AKDGRDSSQHSSVRFETEE-ADRG
FVSGIGTVLKRSPESREDLAHLS---DSSSSSSSIMSFKSADSVKSRPSAPRLEGDGGER
A-SPENRE-PGT----GRK-EEAVESIMRKYLRK-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MGKAKGEPR--------------ESKEAPRGG-----EEAPA-----ES---KAE
QVESKEETGESTDQEQAPKDVWYEAD---KVW--LVQQDGFVLAT---QLKPDVGTPELP
AGRVRVRRDADGSITEVDEDSVQR------------------------------------
------TNPPHLDLA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLATLLNLNECSALNTLQHRYHSHLPYTYAGPSLVAIRPGPTAG
NHA-----GKVS----KGKRDSTA-PHICSVAQRAYRTLLAQRRDQAIVPMGRSGAGKTT
SCQLALEHLVGTVGSVDGRVS-VEKIQAMFTVLGAFGAVSTEQNSSSTRFSMIFSLDFSA
AGRITAAHLQTMLLERGRVAQQAPGESNFNIFPMMLAGLDAAQRTTLHLHQVAESNAFGI
KPFSKPEEKQKASVAFAKLQAAMAVLGITAEEQVAVWRVLASIHHLGAAGACR------V
GRKQFMRFEWATHAAEVLGCELEELSTAVFKHHLKQILAQAAARGGGRPSE-----EEGP
SGQKMTGVE-CVEGMASGLYEELFAALVSMINRSFSSQHLSIASIAVVDTPGFHNPRHQG
GQRAATFEELCHNYVHERLQGLFYERTFVSEMET-YKEENVEVSFDLPERSPSATLSIVD
LNPS-QPQVLP-GSPGADRRGLLWILDEEVLIPGSGDGAAFDR-LCSYFGPKGSDQ----
DGAGCVRRCEQALHFEIPHQLGTDPVRYDLAGWVSKAKLNLSAENASQLLQQSQLNALQE
LAMPRRGVPRVCRAVAGLEGCSQAALQRNACIRKVFASSLAAVRRRSVCAQLKLQADALT
SLLRRSQLHFVHSLVPGTAVEKAD-------------------PLPLDVPALRAQLGGTQ
LLDALRLRR---SGYADRLL----LAHFRRRFQVLAPAVMKKCTSAYEVPDESKAIEELF
QALDLEKKSVAIGRSQVFLKAGVLSRLEKQRDKLIAQKLILLQAACKGFLSRQKFKRLKV
QRLAVRCIQKNVVVFQAVQHWPWWQLLSRVRPLLSVNLAEEQ-LRVKEKELAALRRKLER
SEQSCSELRQNTE-KLESKIVDLTMELSDERHKGDIACQVLDGERAERLRGTRELQELQS
KHDQVQKKLESVQKQLEEAQQLVQLREMKISGS-EGEDVWHVRFDCAQTEIAFLQKRLAQ
LEERLSAELSSRSGLEQKLGEVQVACQAARAAAQQLRRRCRRLTCELEDARVLAESQQSR
NHELEKRQKKFDLQLAQALGESAFERSLREKVVQENSSLRWEMG---KLQQSLEQQQAEG
ASLAQRVSQLAGRVQELSAPG-ALDSCSVPTLRQQLWDLEASTAEQRKELERQTANVDHL
EQLHQRLELEIERMKQIHQKELEDKDEELEDARQSCQRRLRQLEMQLEQEHEEKQTALRE
KQDLEGLVGTLCEQIGHRDLDVEKRLRRDLRRTRALLADAQLLLAAPTEPGA-TG--TAE
LQRLQKQLEESEARCTEAQRSQQAAAQELENLHMEMEMLSRNKTLADEQLIQMQHERDDL
L--RRVSEDQEDLNELMAKHKALIAQSATDIAQIQELQTQVEEVKKEKQSLQE---KLLV
AQASVARLEQRPAERAVISRQEARIRDLESQLDFQAVQMKRFEVLVLRLRDSIIKMGEEL
EKAAESEAREKESTKYYQRRMEEMKADMDELVQRELESSRRRVELEQQ-LAEAVAARQGL
QADLGTAIRRIADLQLALEELRASDDSDAESVQTARDTLCSKRETDACSSVGSVLSLEPA
ESLCSWPGSSIGW--SSP-----TGGSVAGSISALSVGSRSTQGLRDNLKRRSR-L----
-----------------------------FEDLY----AICSLFASEETV----------
-----------CIYT----------EKHPRCTFMPGHVLQCITRR-REY-----------
-G---KPPSDSTE-----LTSP-----LDKP-RARSPLPSASAALSDYVGELRRRRVVER
E--------QGPLPEDTSALPIYRTTGAAALRRS-RPRL-----------GDAGTELLGV
SDGTDSSLPRSSSLRSLVQQPSEP-TLSPVLKRSSKFGSCDSLLLSLGGP---E------
---------LLGPRPWRSRLEPSAEEDGQA---AGW-------ASPGTGLGLGLGGDPCA
WKIPTLGFERRASPELEEFLPAIRKSRSTSSLAKP-GRDRKDGHRALTVRFQDEAVVGDS
ASSRSRSAAQPGLAPGGDRSDSSSSSGSILSSGSILSSRSADSVKQRPWRSDGEGCSGKG
STESSGES--HRAE--AEGKEDDVSSIMRKYLGKE

------------------------------------------------------------
---------------------MAISSRLALWEQKESCIREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRRKAAAFTAPEVEIPAVPTNQTNK--TNN-VPKP-GSQQ
TSQDSSSTTQNSADIPGKEPPG-AGDKDST--PVTSTSGERPQESGPTGTPAKRTLPFKR
GVRRGDVLLMVAKLDPELAKAEQKVQPRDVP------VDKTPAPA-------KDSGGTKK
GVTTGTSSAPQPS---M------PEKTRTRGVGDTGQ----STKGGKC---QGTEGKG-S
RDPQTNGQKEGES-QRTEEQGTRSQAQEAG-NKEQ-----------------------LG
TAEK-GEGPPKKMEKEDEPKVAGA-------------EPPVPLRKWGGFLGRRSKWDSPQ
SKDR-VTESHRKDEKTGDLQSP-----------AVDRSCGQLAEPTGQPAGPTGQPSGPT
GQLSETTGQPSGPTGQLSEST-------GQPPGPTGQPSGPTGQQQ-----EAPVKMEGK
VGRPQKKL---VTPRKPREL-PGVAA--KTQNLEESCKAPDRIPTTG----ISAEAAKRD
GQPESRVQGAREPHVCTEEEV---DVVKPQAEGHVESIPEVGMERL-STLRPMEEKQILQ
DPDRGGQSGD-SDQA-S-EDRWYEAQ---KVW--LVQKDGFTLAT---VLKPDEGTADPP
AGRVRLCIDADRTVIEVDEEQVHP------------------------------------
------ANPSELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLVSVNESSVMNTLLQRYRAQLPHTCSGPDLIALQPQTTTV
PSS-----GKVP----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKLRATFTILRAFGCVSTSHSRRATRFAMVMSLDFNA
TGRVTAAQLQTVLLENSRVAWQPQGEGNFEVFSQLLAGMDVDLRTELNLHQMAESSAFGM
GLWSKPEDKQKAAAAFSQLRGAMELLGILEGEQQAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCDYEELNTATFKHHLRQIIEQMTSGPQRQG---LQ-DNEAC
SGLKMTGVE-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDTPGFQNPRHQG
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YKEEGIPVPFDLPESSPGTTVAVVD
QNPS-QVHLPT-GRGAEDAGGLFWVLDEEVRVEGSSDSAVLER-LRAAFEKKK-EAGA--
EEPPSMRTCEQPLQCELFHQLGRDPVRYDLTGWLRRAKPNLAALEAPQILQQSKREELQS
LFQARAKLPPVCRAVAGLEGTSQQALHRSRVVRRAFASSLAAVKRKAPCAQIKLQMDALI
SLLRRSRLHFIHCLVPTTV-ESKTGQRTPSPSQPSGDQGVVNEPTALDIPALRVQLAGCH
ILEALRLHR---AGYAEHMG----LAQFRRRFQVLDPALLKKLDLTSEELDERKVVEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSQNIVLFQAACRGFLSRQEYKKLKI
RRLATLCIQKNLAVFLKVKDWSWWGL

PF01576 // ENSGT00920000149027_1_Domain_5 (1707, 2143)

LASLRPLLSSTLGTEQ-LRAKEEELTLLRQKLQK
SENSRSELRQNVD-LLESKITDLTSELADERFKGDVACQALESERAERLQALREVQELKT
KYQQVQDALGEVQKQLEEAQQRIQGANLEEKPA-GGAEEWQMRLDCAQMENDFLRKRLQQ
CEERLDSEMKARTELEQKLGELQSAYEEAKKMAHQLKRKCHHLTWDLEDTRVLLENQQSR
NHELEKRQKKFDLQLAQALGESMFEKSLREKVSQENNGVRWELGQ---LQQQLEQKEQEA
SKLKQEVERLQGQKRELLSCA-SVGDQGVASLKERVWELETNALEQEKIHSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQVALHE
KHDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATIEDSKTSIS--KEE
LEKVHSQLEQSEAKCEDALKTQKLLTADLENMHSELENVTRSKSLVDEQLYRLQFEKADL
L--KRIDEDQGDLNDLMQKHKDLIAQSAADIGQIQELQLQLEETKKEKQKLRE---QLHM
AQLRIQYLEQSTVERAIVSRQEAIICDLENKTEFQKVQIKRFEVLVIRLRDSMIKMGEEL
SRAVKAEAQQRENSQYYQQRLEELKAEMQELAQREEEASRRCMELEKY-VEELATVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDTESVQTAVDCSS---RSGKEGDNVSVISSQPE
GSLQSWMSCSL--SLATDSVRIPSRQSVVSSSF---HSPRV----SEEAGDSERLRT---
------------------------------------------------------------
--ASS--ALSGAWDAARDASKAGSASL-----HPVFPQKPYHLGDGEGF-----------
-AVHRKST--LEHSGP-LSSSPPSQRTAVSPPS-RDKLPSPSAALSEFVEELRRKRAQRG
QG-------STLHLGDGPVLPIFQTTRASSLRR-GRASSDEGDLSLKTR-VKSPLGAEGI
PGA-TAGLSRSTSLKCISSEGPED-ITLLPDKQKTRFGSCESLLESGPCT---RKKLSSP
T-----GLLSPTLRPRRPCLESSVDDAISLE--LGKEPLVFQNRQFSHLMEETLDSDPFS
WKLPSLNYRLQTKVDFDDFLPAIRKSDTPSSGA---AKDGKEASKHPGVHFEMGEAADRS
FLSGIKTILKKSPEVKEDPAHLS---DSSSSSSSIVSFKSTGGTGSGPRVPRLQGDGGER
M-SPEHRD-PGS----ARR-DDDVESIMRKYLQQ-

------------------------------------------------------------
---------------------MAISSRLALWEQKE-SIREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQKKQAALVSPEQETPELSASQPNS-KSSS-GTSS-GSQR
ISQDTQSSSPGSSNIPGKDSEG-AGSTSPG--MMTTINGEKAPEPGSGGTPAKKTLPFKR
GVRRGDVLLMVAKLDPDSAKPEQRTPP----------PCKTPPPA-------TDPGGGKK
GETPGTPCGPQAS---TEHLAPKAEKTRTGGVGDADQGTALLTKGRKG---QGTTRKG-D
GAPQTKGPTAGEP-QGKDGQGTRPQAQGPR-EGGL-----------------------SG
TAEKEGGDPPNKVEKGTLPKDAGSEGK--------HAVPPVQARKWGGFLGRRSKWDGPQ
NKQGKEGELLSRAEEKGEQQSK--------------------------------------
-----------AGK-----------GKAGEPEG-----------------------EKGK
AGQAQSK--------------SGETG-GARSPTEKGCKAPGEVDTRG----LSL--AGKE
GWPQRPEQRAQEPCA-G-AGD-AAGARQGALEGPGPPAPEQDADGPGT-RAENPVGPAPQ
EEGTEGPSGD-S--DQAPKDRWYEAE---KVW--LVQKEGFALAT---VLKPDEGTADLP
AGRVRLCIDTDKTITEVDEEYVHR------------------------------------
------ANPPELDH

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1517)

VEDLTSLISVNESSVLNTLLQRYRAQRLHTCTGPDLIVLQPQGASA
PSA-----GKVP----RGRRDGLS-AHVGSLAQRAYWALLSQRADQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVEGRVS-VEKIRATFTILRAFGSVSTGHSRHATRFAMVMSLDFSA
TGRVTAAQLQTMLLEKSRVARRPEGEGNFQVFSQMLAGLDLDLRTELYLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLRGAMELLDISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTSTFKHHLRQIIQQVTLGSSRRG---LE-EEETS
SGLKMTGGE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYVHERLQLLFYQRTFVSTLER-YRAEGVPVQFDLPEPSPGATVAVVD
QNAS-QVRLPA-GGGVDDAQGLFWVLDEEVRVEGSSDSTVLER-LCAAFEKKGAGA----
EGTSALRTCEQPLQCEISHQLGRDPVRYDLTGWLQRAKPNLSALEAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSRVVRRTFAGSLAAVRRKAPCSQIKLQMDALT
SMIRRSRLHFIHCLVP

ENSGT00920000149027_1_Linker_1_3 (1517, 1553)

HPVVESRGGQGSSTPLEPGGDKPGAGGPPAPDIPAL

PF00063 // ENSGT00920000149027_1_Domain_3 (1553, 1640)

RVQLAGSH
ILEALRLYR---TGYADHMG----LAQFRRQFQVLDPPLLKKLMTTSEGIDERKAVEELL
QTLDLEKKAVAMGHSQVFLKAGVVSKLEKQREKLMSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELMTLRQKLEK
SEKSRNELRQNAD-LLESKIADLTTELADERFKGDVACQVLEGERAERLQAFREVQELKS
KYEQVQKNLGEVEKQLEEAQQKIQLHALERDRT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTCRKELEQKLAELQSAYEGAKKTAHQLKRKSHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSIRWELGQ---IQQQLKQKEEET
SQLKQEVKMLQDHKQELLKSP-SLGENCIAGLKEKLWKLESGALEQQKIQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLQQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLADVQLLLGTMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEEALKIQKVLTADLESMHSELENMTRSKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKELIAQSATDIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQTRIEHLEQSTVDRAIVSRQEAVICDLENRTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAAASESQQRESSQYYQRRLEELKADMAELARREAEASRRCMELETY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDSESVQTAVDCGS---GGRKEMDNVSILSSQPE
GSLQSWRSCTL--SLATDAVRTPSRQSASSSHI---RGPR----MNEEAGDAEMAQW---
------------------------------------------------------------
--AS---VLSRA--QDVRSKSSGDKPV---SPHSLRRQKYCHFGDGEGS-----------
-GVNTKPT---ERLEA-RSSPLASRSADTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRASSDEGDLSLRFG-SKSPLELEGA
AG-TSAGLPRSTSLKCISSDGVEG-TSLLPEKPKTRFSSCESLLESTPNL---GRKLSSP
TR-PRDVLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGRDPFT
WKLPSLDYARKTKVDFDDFLPAIRKPDTPTSLARA-AKDRQDASKRSSVHFETEE-ADRS
YLSGIKTILKKSPEPREDPAHLS---DSSSSSSSIVSFKSADSIKSRPGVPRPAGDGGER
T-SPEHRE-PGA----GRK-EDDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKEAALASPERETPEISTSQPNS-RSSS-GTRS-GSQQ
ISQDIQPSSPGSSNILGKESEG-VGSTSPV--TMTTLDGEKAQELGSGGAPGKKTLPFKR
GVRRGDVLLMVAKLDLDAAKPEQRTPPRDEL------PCKTPPPA-------TDPGGERK
GNTPGTPSGPQAS---TEHLGPKAEKTRTGDVGDPDQGSALLTKGRKG---QGTVGKG-D
GLPQTKGPTGSEP-QSKDQEGT-----GPA-EGEL-----------------------SR
AAEKVGGDFSDNVEKGNISKGAGSERK--------HAVPQIQVRKWGSFLGRRSKWEGLQ
SKSDKEGELPSKAEKTSEPQGRVRE------------------------------PGKEQ
EG-REKAGGRPSEA-----------AKAGEPGG-----------------------EKGK
VGQLQSR--------------SGEAG-GAQSPTGKGSREVDLR--------KTP--SGKE
GQPESPEQRAEELCARTRVGD-GAG--ARELAGPRQPALEKCTERPAK-QAENRAGPAPQ
EEGAGSRSGD-S--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTITEVDEEYVHR------------------------------------
------ANAPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1519)

VEDLTSLISVNESSVLNTLLQRYRAQLPHTRTGPDLIVLQPQGASA
PSA-----GKVH----SGRQDGLP-THIGSLAHRAYWALLSQRKDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVEGRVS-VEKIRATFTILRAFGSVSAGHSRHATRFAMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGEGNFQVFSQMLAGLDLDLRTELYLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMEILDISESERRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTSTFKHHLRQIIQQVTFGSGRRG---LE-EEETG
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFFSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYVHERLQLLFYQRTFVSTLER-YRAEGVPVQFDLPEASPGPTVAVVD
QNPS-QVRLPA-GGGTEDAKGLFSVLDEEVRMEGSSDSTILER-LCAAFEKKGAGA----
EGTSALRTCEQPLQWEISHQLGWDPVRYDLTGWLHRAKPNLSALEAPQILQQSKREELRS
LFQARAKLPPVCWAVAGLEGTSQQALKRSRVVRRTFAGSLAAVRRRALCSQIKLQMDALT
SMIRRSCLHFIHCLVPNP

ENSGT00920000149027_1_Linker_1_3 (1519, 1553)

VVESRDGQGSSVPLEPGGDKPGTAGLLAPDIPAL

PF00063 // ENSGT00920000149027_1_Domain_3 (1553, 1640)

RVQLAGSQ
ILEALRLHR---TGYADHMG----ITQFRQQFQALDPPLLKKLMSTSEGIDERKAVEELL
QTLDLEKKAVTVGHSQVFLKAGVVSRLEKQREKLVSHSIVLFQAACKGFLSRQEFKKLKI
RRLAAGCIQKNVAVFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELRVLRQKLDK
AEKSRSELRQNAD-LLESKIADLTTELADEHFKGDVACQVLESERAERLQASREVQELKS
KYEQVQKNLEDVQKRLEEAQQKIQLNALERNCT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEGRLDSELTCRKELEQKLTELQSAYEGAKKTAHQLKRKSHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGECVFEKGLREKVTQENTSVRWELGQ---LQQQLKQTEQET
LQLKQEVEMLQEQKRELLKSP-TLGENSVAALKERLWKLEAGALEQQKIQNQQKNTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGTMEDSKTSVS--KED
LEKVHSQLEQSETKCEEALKTQKVLTADLESMHSELEGMTRSKSLVDEQLYRLQLEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSSADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAIICDLENRTEFQRVQIKRFEVLVIRLRDSLIKMGEEL
SQAAASESQQRENSQYYQRRLEELKADMEELAQREEEASRRCMEMEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEV-AS-DSDTESVQTAVDCGS---GGRKEMDNVSVLSSQAE
GSLQSWRSCTL--SLATDPVKSPSRQSITSSHI---LSPRH--RMNEEAGDAETTQP---
------------------------------------------------------------
--VS---ALRRA--QAARSTISGDKSV---SPHSVRQKKYCHFGDGEGF-----------
-GVERKSM---ERLEA-PSSSKESHSRDTSPLSRGGKLPSPSAALSEFVIGLRRKRAQRG
QG-------SMLGLEDWPTLPIYQTTGASTLMR-GRASSDEGDLSLRYG-TKSPVEMEGA
SG----SLPRSTSLKCISSDGVGG-TALLPEKPKTRFSSCESLLESTPNL---GRKLSSP
SA-PRDTLSSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFT
WKLPSLNYERKTKVDFDDFLPAIRKPETPTSLARA-AKDGQDSLRHSSAHFEMED-TDRS
LLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPRVPRLAGDGGEQ
T-SSEHRE-PET----GSK-ADDVESIMKKYLQK-

------------------------------------------------------------
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------------------------------------------------------------
-----MCRRGKG--GTWIPVCASQ------------------------------------
------ANPPGLDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1637)

DDLASLVSVNESSVLNTLLQRARAQLLHTRAGPDLVFLQPQEPAA
PSA-----GKVP----KGHRDGLP-AHISSLAQQAYWAMLSQRRDQSIIALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTILRAFGSACTGHSCSATRLAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVAWQPEGEGTFPVFSQMLAGLDPDLRTELYLYQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMDTLGITEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANRAAEALGCEYEELNTATFKHHLRQIIEQVTSGPSRWG---LK-DEEPS
SGLKMTGTE-CVAGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYLHERLQLLFYQRTFVSVLEQ-YHEEGIPVPCDLPEFSPGTTVAIVD
QNPS-QVHLPA-GGGTEDARGLFWVLDEEVRIEGSQDSVVLER-LCAAFEKKGAGTT---
-ESPPCMPPCQPLQCEIFHQLGQDPVRYDLKGWLRRAKPNLAALDAPQLLQQTKREELRS
LFHGRAKLPPVCQAVTGLEGTSQQALHRSHVVKRTFASTLASTRRRAPCSQIKLQMDALI
SLVRRSQLHFIHCLVPTSAVDSKGL--------P-GDQPGAGKVLAPDIPSLRVQLAGSH
ILEALRLHR---TGYADHMG----LTQFRRRFQVLDPVLLKKLMSAPEGIDERKVLEELL
ETLDLEKTLVAVGHSQVSKVSS--------------------------------------
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---------------------------------------------------------MAI
SSRLALWEQ---KIREEDKSPPP-------------------------------------
------SSPPP---------LFSVIPGGFIRQLVRETEKESKEARRRKEAA-----LASP
ERE-----VPVP----RGRWDRSP

PF00063 // ENSGT00920000149027_1_Domain_1 (925, 1516)

-AHVASLAQRAYWALLSQRRDQSVVALGRSGSGKTT
CCEQVLEHLLAMAGSVDGRVS-AEKIRATFTVLRAFGCASTGHGRSATRFAMVMALDFNA
TGRVTAAQLQTALLETSRVARRPAGEGSFHVFSQMLAGLDLDLRTELHLHQLAASSSFGL
GVWAKPEEKQKAAAAFAQLQGAMETLGISASEQQAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSRPSRRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMGSIMVVDSPGFQSPRHEG
KERAATFEELCHNYVHERLQLLYYQRTFVSTLER-HREEGVPVQFDLPERSPATSVAVVD
QSPS-QVPLAA-GGGAEDAGGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGA----
EGTSALRACEQPLQCEIFHQLGHDPVRYDLTGWLHRAKPNLAALDAPQVLQQSKREELRN
LFQARAKLPAVCRTVAGLEGTSQQALQRSRVLRRTFASRLAAVRRRAPCSQIQLQTDALI
NVIRRSHLHFIHCLA

ENSGT00920000149027_1_Linker_1_3 (1516, 1551)

PTPLLESRTGQGSPTPPQPGGDETKAGGPPALDIP

PF00063 // ENSGT00920000149027_1_Domain_3 (1551, 1640)

ALRVQLAGSH
IMEALRLHR---AGYADHMG----LTQFRRRFQVLDPPLLKKLVLASEGVDERKAVEELL
QSLDLGKKAVALGHSQVFLKAGVVSRLEKQREKLVSQSIILFQAACKGFLSRQEFKKLKI
RRLAARSIQRNMAVFLAVKDWPWWRLLGSLRPLLSSSIGSEQ-

PF01576 // ENSGT00920000149027_1_Domain_5 (1724, 2142)

LRAKEEELTALRHKLEK
SEKLRNELRQNTD-VLESKIADLTTELADERFKGDVACQVLESEWAERLQASRELQELKS
KYEQVQKKLGEVEKQLEEAQQKIQLSDLERNRP-GGADEWQMRLDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQGAYEGARKAAQQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDMQLAQALGESVFEKSLREKVTQENTSVRWELGQ---LQQQLQKKEQEA
SQLKQEVEILQDQKRELLGSS-SMGEDCVAALKERLWKLESSALEQQKIQGQQESTIKQL
EQLRQQFELEIERMQQMYQKDREDKEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMALHE
KQDLEGLIGTLCEQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTADLETMHSELENMTRNKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNELMQKHKDLIAQSASDIGQIQELQQQLEEAKKEKHKLQE---QLQV
AQMRVEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SRAAASEAQQRESSQYYQRRLEELKAEMEELVQREAEAGRRCVELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGA---GGQRELDNVSVISSQPE
GSLQSWSSCTL--SLAADTMRSPSRLSTISSRI---PSPRM----SEEAGDAERPRP---
------------------------------------------------------------
--AS---ALSRAWDD--RGKTPGETSL---SPGSVRRHKSCHFGDGEGV-----------
-GAQRKAT---ERSGA-LSASLASRSPDTSPLP-RAKLPSPSAALSEFVEGLRRKRAQKG
PG-------SRLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGDLSLRA-GGISPLETEGA
AG-TSAGLLRSTSLRCIPSEGAQG-TAMLPEQRKTRFSSCEALLESGPGS---WRRLSPS
TA-PGGMLLSPPLRPRRRCLEASVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLDSDPGS
WKTPSLHYERKTKVDFDEFLPAIRKPGASTSLVRA-SKDGASGPQAPSVHFETED-ADRG
FLSGIKTILKKSPEPREDPAHLS---DSSSSSSSIVSYKSADSIKSRPGLPRLQGDGGER
T-SPESRE-PVP----GRR-EDDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK-----EKDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALASPEPEIPEISISQPNS-KSSS-GTRS-GSQQ
ISQDDQSSSPGSSDILGKESEG-SRSPDPE--QMTSINGEKAQELGSSATPTKKTVPFKR
GVRRGDVLLMVAKLDPDSAKPEK-THPHDTP------PCKSPPPA-------TDTGKEKK
GENSRTPCGSQAS---TEILAPKAEKTRTGGLGDPDQGTVALKKGEEG---QSIVGKG-L
GTPKTTELKEAEP-QGKDRQGTRPQAQGPG-EGVQ-----------------------PG
KAEKEGAEPTNTVEKGNVSKDVGSEGK--------HVRPQIPGRKWGGCLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----M---------------EKTSQVQGE---LGDDL
RM-GEKAGELQSMT-----------GKAGESWD-----------------------KKEK
MGQPQGK--------------SGNAG-EARSQTEKGCEVPKEVSTMV----ESPAAPGKG
GWPGSRGQEAEEPCSRAGDGA---GALETELEGPSQPALEKDVERP-RIQKENQDGPAPQ
EEGKGGQSRD-S--DQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKTITEVDEEHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1521)

VEDLASLISVNESSVLNTLLQRYKAQLPHTCTGPDLIVLQPRGPSA
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYGALLNQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGVAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWG---LE-DEETS
SGLKMTGVD-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YQEEGVPVPFDLPDPSPGATVAVVD
QNPS-QVRLPA-GGGAQDARGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLSGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCFQIKLQMDALT
SMIKRSRLHFIHCLVPNPVVESRSGQESPTPPQPGRDKPGAGGPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTDLADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQQVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQVATQEAEAGESLEPG---------------SLGNKSETVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKLGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSATSSRI---LSPRI----NEEAGDTERTQS---
------------------------------------------------------------
--AL---ALSRARSTDVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKST---ERLEP-ASSRLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRHTLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSQRSSIHFETEE-ANRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDGGER
T-SPEQRE-PAT----GRK-HDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK-----EKDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKRSALASPERETPEIPISEPNS-KSSG-DTRP-GSQQ
ISQENQSSSPGSSNILGKASKG-ASSPDPE--RMTSINGEKAQELGSSATPAKKTLSFKR
GVRRGDVLLMVAKLDPDSAKPER-THSHDTS------SCKTPSPA-------TDPGKEKK
GETSRTPCDPQAS---TETLAPKAEKTRTGGLGGPGQGTAALKKGEKG---QSTVGKA-G
GAPKTKELKEGEP-QGKDSQGTRPPAQGPS-EGLQ-----------------------AG
TAEKEGGEPTNTVEKGDVSKDVGSEGK--------HVRPQIPGRKWGGFLGRRSKWDGPQ
NK-DKEEVLLSKGGKTGEPQTQ-----T---------------EKTSQVQGK---SGDDL
RM-GEKAGELRSST-----------GRAGESWD-----------------------KKEK
MGQPQGK--------------SGKAG-EARSWIKKDCEAPNEVSTMV----EPPAAAGKG
GWPGSRGQEVEEPCLRADDRA---GALETEPEGLSQPPLEKDAERP-RIPKDNQDGPAPQ
EAGKGGHSRD-A--DQVTGLQLWERGGADGAL--HRQRDGKDLPPGMDKGWPDEGTADLP
AGRVRLCIDADKTVTEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1519)

EDLASLISVNESSVLNTLLQRHRAQLPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----RSRRDGLP-AHIGSMAQRAYWALLNHWRDQSIVALGRSGAGKTS
CCEQVLEHLVGMAGSLDGRVS-VEKIRATFTILRAFGSVSVAHSCSATRFTMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGGSNFQVFSQMLAGLDLDLRTELNLHHMGESSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQVTFGPSRWG---LE-DEEAS
SGFKMTGME-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLER-YREEGVPVQFDLPDPSPGATVAVVD
QNPS-QVRLPA-GGGAQDARGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRACEQPLQCEIFHQLGRDPVRYDLTGWLHRAKPNLSALDAPQILQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALI
SMIKRSQLHFIHCLVLNPVVESRNGQESPMPPQPGRDKPGAGGPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVVVGHSQVFLKAGVIARLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWSWWQLLGSLRPLLSATIGNEQ-LRAREEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KYEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGDLQSAYEGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQET
LQLKQEVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSAIEQQKIQSQQESTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEHSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSHYYQRRLEELKADMEELMQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQTE
GSLQSWLSCSL--SLATDTVRTPSRQSATSSHI---LSPRI----NEEAGDAERTQL---
------------------------------------------------------------
--MS---ALSRGWSTDVRGKTSGDKPV---SPHFARQQKYSHLVDGEGL-----------
-TIQRKST---ERLEA-ASSPLASRSANTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
HG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLSRSTSLKCISSDGDGS-TTLLPEKAKARFSSCESLLESRLSM---GRKLGSP
TT-PRDTLLSPVLRPRRRCLESSVDDAACPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLNYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQGGSQRSSVHFEPEE-ADHT
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDGDER
T-SPELRE-PGT----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLTLASLERETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-VGSPDPE--RMTSINGEKAQELGSSATPAKKTLPFKR
GMRRGDVLLMVAKLDPDSAKPER-THPHDTP------PCKTPPPA-------TDTGKEKK
GETSGAPCDPQAS---TEILAPKAEKTRTGGLGDAGQGTVALKKGEKG---QSIVGKG-G
GTPKTKELKEAEP-QGKDRQGTRPQAQGPG-EGVR-----------------------PG
KAEKEGGEPTSPVEKENISKNVGSEGK--------HVGPQIPERKWGSFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----T---------------EKKNQMQGE---LGDDL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAERPCSREDVGS---GALETELEGPSQPALEKDAERP-RIQKENQDGLAPQ
EAGKGGQSRN-S--EQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTA
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPEPSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRNRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVLNPVVESRSEQESPTPPQPGRDKPGAGAPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIILFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLG

PF01576 // ENSGT00920000149027_1_Domain_5 (1709, 2141)

SLRPLLSATIGNEQ-LRAKEEELTTLRWKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQEVEMLQDHKRELLGSP-SLGENCVASLKERLWKLESSAVEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDKEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLYELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGTVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGKKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTMRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----PSRAWSTDVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKAT---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGG-AKGGQDGSQRSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK-----EKDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKRSALASPERETPEIPVSQPSS-KSSG-GSRP-GSQQ
ISQENQSSSPGSSDILGKASEG-AGSPDPE--RMTSINGEKAQELGSSATPAKKTLPFKR
GVRRGDVLLMVAKLDPDSAKPER-THSHDTP------SCKTPSPA-------ADPGKEKK
GETSRTPCGPQAS---TEILAPKAEKTRTGGLGDPGQGTVALKKGEKG---QSIVGKA-G
GVPKTKELKEGEP-QDKDSQGTRPPAQGPS-EGVQ-----------------------VG
TAEKEGGEPTNMVEKGDVSKEAGSEGK--------HVGPQIPGRKWGGFLGRRSKWDGPQ
NK-KDKEVLLSKGRKTGEPQTQ-----M---------------EKTSQVQGK---PGDDL
RV-GEKAGELQSST-----------GRAGESWD-----------------------KKEK
MGQPQGK--------------SGKAG-EVRSQIKKGCEAPNEVGTMV----EPPAAAGKG
GWPGSRGQEVEEPCSRADDRA---GALETELEGLSQPPLEKDAERP-RIPKDNQDGLAPQ
EAGRGGHSRD-A--DQAPEDRWYEAQ---KVW--LAQKDGFILAT---MLKPDEGTADLP
AGRVRLCINADQTITEVDEEHVHR------------------------------------
------ANPPELDQAEDLASLISVNESSVLNTLLQRHRAQLPHTCTGPDLIVLQPRGPSM
PSA-----GKVP----RSRRDGLP-AHIGSMAQRAYWALLNHWRDQSIVALGRSGAGKTS
CCEQVLEHLVGMAGSLDGRVS-VEKIRATFTILRAFGSVSVAHSCSATRFAMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHHMAESSSFGM
GVWSKVRRKS-----FGILRGPLG---INSPS-------VQGLTAMPLFCPRA------V
GRKQFMRFEWANY

PF00063 // ENSGT00920000149027_1_Domain_1 (1154, 1519)

AAEALGCEYEELNTATFKHHLRQIIQQVTFGPRRWG---LE-DEEAS
SGLKMTGME-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYTHERLQLLFYQRTFVSTLER-YREEGVPVQFDLPDPSPGATVAVVD
QNPS-QVRLPA-GGGAQDARGLFWVLDEEVRVEGSSDSVVLER-LCTAFEKKEAGT----
EGSSALRACEQPLQCEIFHQLGRDPVRYDLTGWLHRAKPNLSALDAPQILQQSKREELRS
LFQARAKLPPVCRAVGGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALV
RMIRKSQLHFIHCLVLNPVVESRNGQESPTPPQPGGDKPGAGRPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLEKQREKLVSPSIVLFQAACKGFLSRREFKKLKI
RRLAAQCIQKNVAVFLSVKDWPWWQLLGS

PF01576 // ENSGT00920000149027_1_Domain_5 (1710, 2141)

LRPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-TLESKIADLTTELADERFKGDVACQVLESERAERLQAFREIQELKS
KYEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-G-ADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYEGARKMAQQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQET
LQLKQEVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSAIEQQKIQSQQESTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQVGKPLFALPLA--------PAAHPSPSHLALTSDCLPQVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKMEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSHYYQRRLEELKADMEELMQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAVLEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSATSSHI---LSPRI----NEEAGDAERTQP---
------------------------------------------------------------
--VS---ALSRGWSTDVRSKTSGDKSV---SPHFTCRQKYSHLGDGEGV-----------
-TTQRKST---ERLEA-VSSPLASRSANTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
HG-------STLGLEDWPTIPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
T----GGLSRSTSLKCISSDGVGS-TTLLPEKAKARFSSCESLLESRPSM---GRKLSSP
TT-PRDTLLSPVLRPRRRCLESSVDDAACPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLNYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQGGSQRSSVHFEPEE-ADRT
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDGDER
T-SSELRE-PGT----GRK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARLRKEAALASPEQETPEISTSQPKS-RSNS-GTKF-GNQQ
IIQGNQSSSPQNSNIPAKESEG-ASPTDPV--PMTSINGEKPQESGTGVTPAKKPLPFKR
GVRRGDVLLMVAKLDPDSAKPEQQTQPPDAP------TCKTAPPA-------TDPGGEKK
GGTPGTPHGPQAG---TKDSASKAEKTQTEGVGDPGK--VLPT----K---QGSGKKG-G
GAPQTKGLKGGEV-QGREGPW----------EGER-----------------------QE
TAEKGGGNPPNKMAKGNLSKE-GGEGK--------GAGAQIQVRKWGVSLGGRSKWDGSQ
SKKDKEGMRPRKSEKTEEPQSK-----E---------------NKVSQGQGQPGKVGGAP
GQ-VEKVGEPQSVP-----------GKAAEPQA-----------------------KVVK
KGQPQGE--------------SGEAG-KAGGKTEKGRTAPEEVGAGR----ETPVPAGKE
GQPESREQKAGESCVGADDGA---KTLETEPEGPRLSALEGQAERP-QTQKESEEGPDRL
EGSK-----D-L--DQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLLIDADKTITEVDEEHVHRDLYSCWYLQFVVGPRPLTCEEPRLHPNPRALGPENS
LKLERIANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLVSINESSVLNTLLHRYRAQLPHTFKGPDLIVLQSPGPPA
PSA-----GKVP----RGRRDGLP-AHLASLAQRAYWVLLSQRRDQSIVALGRSGAGKTT
CCEQLLEHLVAMAGGVDGRVS-VEKIRATFTVLRAFGSVSTGHSYNATRVAMVMSLDFNA
TGRVAAAQLQTMLLEKSCVARQPEGEGNFEVFSQMLAGLDLDLRTELYLHQMAESHSFGM
GIWPKPEDKQKAEAAFAQLRCSMETLDISEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTSGPSRRG---LE-EEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQC
KDRAATFEELCRNYAHERLQLLFYQQTFVSTLER-YRQEGILVPFDLPEPSPGTTVAVVD
QNPS-QVRLPA-IGGAEGARGLFWLLDEEVRVEGSSDSVVLER-LCAAFEKKGAGA----
EGTSAFRSCEQPLQFEIFHQLGQDPVRYDLAGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQSRAKLPTVCRAVAGLEGTSQQALQRSCAVRRAFASSLAAVKRKAPCSQIKLQMDALT
SVIRRSQLYFVHCLAV----ASGGRQGSLTPLQPGRDKPGTGEPLPLDIPALRVQLAGSH
ILESLRLHR---TGYADHVG----LPQFRRQFQVLDPVLMKKLMLASEGIDERKAVEELL
QTLDLEKKAVVIGHSQVFLKAGLVSRLERQREKLASHKILLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNMAVFLEVKDWSWWQLLVSLRPLLSATIGDEQ-LRAKEAELTMLRQKLEK
SEKSRNELRQNAD-LLESKIADLTTELADEHFKGDVACQVLESERAERLRTCREVQELKS
KYEQVQKNLGEVQKQLEEAQQKIQLNDLERSHT-RGADEWQMRFDCAQMENEFLRKRLQQ
FEERLDSELTSRKELEQKLAELQSAYEGAKKMAHQHKRKCHHLTCDLEDTRLQLENQQSR
NHELEKKQKKFDMQLAQALGESMFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQET
SQLKQEVETLQAQKRELLGLS-SLGESCVAGLKERLWKLESSALEQQKIQNQQKNTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGNMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTVDLENMHSELENMTRSKNLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSATDIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVKRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
TQAAKSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCSS----NRKEIDNVSVLSSQPE
GSLQSWLSCTL--SLGTDIMRTPSRQSASSSPI---LSSRM----KDESRDAERSQP---
------------------------------------------------------------
--AS---ALSRA--RTMQSQTSGDKSV---SPLCLRRQKYYHPGDGDEC-----------
-GGQRKPA---QRLGT-RSSSPASRSTDTSPAS-REKLPSPSAALSEFVEGLRRKRAQRG
RG-------SPLGLEDWPTLPIYQTTGASALRR-ARAGSDEGALSLGFGVKSAL-EQEGA
SG-TSAGLLRSTSLKCISSQSTEG-TTQPPEKLKTRFSSCESLFESGQSS---GRRLSPP
SS-SRSLLLSPTLQPRRRCLESSLDDGGCPD--LGKEPLIFQNRQFAHLMEEPLDSDPFT
WKVPSLNYERKTKVDFEDFLPAIRKPESPVSLARA-PKEGQDSPRHSRIHFETEE-ADRT
FLSGIKTILKKSPESKDDPAQLS---DSSSSSSSIVSFKSADSIKSRPRIPRLEGDGGEQ
T-SPEHRE-PGA----GSK-DEDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALAAPDRETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-AGSPDPE--RMTSINGEKAQELGSTATPAKKILPFKR
GMRRGDVLLMVAKLDLDSAKPER-THPHDTS------PCKTPPPV-------TDTGKEKK
GETSRAPCGPQAS---TEILAPKAEKTRTGGLGDAGQGTVALKKGEKG---QSIVGKG-H
GTPKTKELKEAEP-QGKDRQGTRPQAQGPS-EGVQ-----------------------PG
KAEKEGGEPTSPVEKENISKNVGSEGK--------HRGPQIPGRKWGGFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----T---------------EKKSQMQGE---LGDDL
RM-QEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAEGPCSREDVGS---GDLETELEGPSQPALEKDVERP-GIQKENQDGPAPQ
EVGKGGQSRN-S--QQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1521)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRWDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTA
CCEQVLEHLVGMAGSVDGKVS-VEKIRATFTVLRAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRD---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPDLSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVRVEGSSDSVVLKR-LCAAFEKKGAGT----
EESSALRTCEQPLQCEIFHQLGWDPVRYDLMGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARSKLPPVCRAVAGLEGTSQQALQRNRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVPNPVVESRSEQESPTPPQPGRDKPGAGAPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKVVALGHSQVFLKAGMISRLERQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAVQCIQKNVAVFLAVKDWPWWQLLGSLRPVLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDSERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
LQLKQEVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTMRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----LSRAWSADVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKST---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-MTLLPEKAKTRFSSCESLLESRPNM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQMPTSLAGA-AKGGQDGSQRSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVTSIMKKYLQK-

------------------------------------------------------------
-------------------------------------IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARQRKQAALASPERETPEISASQPNS-KPDS-GTKS-GSQQ
ISQDNQESSPQNSNVPVKESEG-AGTTDPV--LMTTINGEKPQESSPSGAPAKKPLPFKR
GVRRGDVLLMVAKLDPDSAKLEQRTQPHDAP------ACKTSPIA-------TDPGGVKK
RETPPTPRGSQAS---TEDAASKSEKTQTGGLGNPAT--VLLTKGGKD---QGITGQR-G
EVPQTKELKEGEP-QGKEGPG----------EAGR-----------------------PG
TVEKRGGDPPNKMAKGNLSKDAGGEGK--------LAGAQIQVKKWGGFLGRRSRLDGPQ
KT-DKEGMLPSKAEKTDKPQIK-----A---------------EKMDKVQGEVGKVKEAP
RV-MEKADGSQSE-----------------------------------------------
---------------------SQEAG-EAGGETEKGREASKEVDACR----ETPAAAEKE
GQPDGRGQQAEEPCARLDDKA---KALVMELEGPRPPALESHAGRPQT--QETREGPAPQ
EEGKGGQSGD-S--DQASEDRWYEAE---KVW--LVQKNEFTLAM---VLKPDEGTADLP
AGRVRLCIDADKTITEVDEEHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

AEDLASLVSVNESSVLNTLLHRYRAQLPHTCTGPDLIVLQPREPWA
SSA-----SKVP----RGRRDGLS-AHIGSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCQQVLEHLVGMAGSVDDSVS-VEKIRATFTILRAFGSMSTGHSLSATRFTMVMSLDFNA
TGRVTAAQLQTMLLEKNRVARQPEGEGNFEIFSQMLAGLDPDLRTELYLHQMADSSSFGM
GIWPKPEDKQRAAAAFTQLQDAMKMLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCEYEELNTATFKHHLRQIIEQVTCGPSRRG---LV-DEETS
SGLKMTGVE-CVEGMASGLYQELFATVVSLINRSFSSHHLSMASIMVMDSQGFQNPRHQA
KDRSATFEELHINTHE---LQLSYQRTFVSSLER-HREEGLPVQFDLPEPSPGTTVALVD
QNPSQXXXXXX-XXXXXXXXXXXXXXXXXXX-----XXXXXXX-XXXXXXXXXXXXXXXX
XXASALRQCEQPLQCEISHQRGQDPVRYDLTGWLHKAKPNLSARDAPQILQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRNCAVRRAFASGFAASKRKASCSQIKLQMDALT
SVVRRSHLHFIHCLVPSLAVESRGGQGSPTLLQPGGDKPGVGRPLPLDIPALRVQLAGSY
ILEALRLHR---TGYADHMG----FTQFRRRFQVLDPLLMKKFMLVTEGVDERKAVNELL
QTLDLEKKAVAMGHSQVFL

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KAGVISRLEKQREKLV

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

SHSIILFQAACKGFLSRQEFKKLKI
HRLAAQCLQKNMAVFLAVKDWPWWQLFGSLRPLLSATVGDEQ-LRAKEXXXXXXXXXXXX
XXXXXXXXXXXXX-XXXXXFADLTTELADERFKGDAACQVLESERAERLRTSREVQELKS
KYEQVQKKLREVEKQLEEAQQKIQLNDLERSHT-GGEDEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTSRKELEQQLGELQSAYEGAKKMAHQLKRKCHHLTCDLEDTRFLLENQQSR
NHELEKKQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXQKEQET
SQLKQEVEMLQAQKRELMGSP-SLGGNCVAGLKERLWKLESSALEQQKIQNQQENTIKQL
EQLRQRFELEIVRMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLKRTHALLSDVQLLLGTMEDGKASVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTADLESMHSELENVTRNKSLVDEQLYRLQFERTDL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGLIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAIICDLENKREFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAAMAEAQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-IEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEIDNISILSSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSALSSHI---LSPRM----NEEAGDAKRTPR---
------------------------------------------------------------
--AL---ALSRA--RDIPSKTTGDKSL---SPLSLHRQKYCHLGDGKEC-----------
-DVQRKPT---ERLGA-LSSSPSSQRTDTCPVS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------PALGLEDWPSLPIYQTTGASTLRR-TRTGSDEGHLSLRCR-AKSSLETEDT
AG-ASAGLLRSTSLKCIPSESMEG-TPLLPKKLKTRFSSCESLLESGPDS---GRKLSSP
TI-PRGTLLSPTLCPRRRCLESSLDDADCPD--LGKEPLVFQNRQFTHLMGEPRGSDPFS
WKLPSLNYERQTKVDFDDFLPAIRKPEMSMSLARA-AKDGQDRSQHSSVHFETEE-TDQT
FLSGIKTILKKSPEAKEDPAHLS---DSSSSSSSVVSFKSADSIKSRPRIPRMEGDGGER
T-TPDSGE-PGA----GRK-DEDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKEXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXAPENSDSPVY------------RSHKPSGTQ
SPQGGQPDSPPVPDIPN---EK-EGMASSEPVLMSTINGENPQGKS-TMTPPKKPQPLKR
TRKTSDVLLMVAKNAELPKSKESRAEPK--------------------------------
-----------------------QERQITR-----------------T---Q-WTG----
----------KEA-K---------------------------------------------
------------------------TR---------KGRQSPHPKRWGESLNKWRKRSGSQ
SQVRKDSESQTQGRKESEPQSQGKGKWI---------------PK-------SDRESVDP
RV----------------------------------------------------------
VGK---------------------R---DVS--KKGREE------------EDPS-QGRK
WQQSSRRRKGGDAT----------------------------TEKEGGEKKETKETPAKM
EEEEDGEGGQSVDPDKELDDRWYEAE---KVW--LVQKEGFTLAT---VLKPDVGTPELA
AGRVRLCIEADKSITEVDEENIHR------------------------------------
------ANPPELDL

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

AENLASLQSLNESSVLNTLQHRHQAQLPHTYTGPDLILLQPQGAQA
PLS-----WKVP----KGRRDGLV-PHVCSLAQKAYWAMLSQRQDQTIVPLGRSGSGKST
CCERALEYLVGSVGTVDGQVS-VEKIHATFTILRAFGSVLTDHSYSSTRFSMVMSLDFNA
MGRITAAHLQTMLMERVRVAQRPEGEGNFAVFSQMLAGLDLDTRTELYLHQMAESHSFGM
GVWAKPEEKQKAAAAFSHLQGAMETFGFSASEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEVLGCEYEALTTAVFKHHLRQIIQQATSRLNQPN---HK------
EEPKMTGVE-CVQGMASGLYEELFGIIVSLINRSLASSHLSTFSIMVVDSPGFHNPRHQK
KERAATFEELCHNYVHERLQTLFFRKKFESELER-YREEKVVVPFDLPELSPRTTVAIID
QNLS-QVHVPV-AGQAEEPKGLLWVLDEEVRIEGSGDSAVMER-LCLAFEKKEAGA----
DEPPAFRKCEHGLQFEISHQLGRDPVRYDLSGWIQKAKPNLSAMNATQVLQQSTREDLSS
LFLPRSRVPPVCRGVTGMEGCSQKAFHRVGCVRKTFASSLAAVKRKAVCTQIILQMDALT
NVIKRSQLHFIHCLVPRSGSEDREAPT-----------WHQHRENPIDISILRVQLAGAQ
VLDALRLHR---IGYTDHMS----FTRFRRQFQGLAPAFMQKHLLPHERVEERKLIEELL
QELDLGKAAVQLGNTQVFL

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KSGVVSRLEKQREKLI

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

SQNIILFQAACKGFLSRQKFKKLKX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXEELTALRKKLET
SEKSRNELRQNTD-LLESKITDLTTELSDERFKGEVACRVLESERAERLRASREIQELKS
KYEQTQKSLGSVEKQLEEVQQKIELCEVGKSHS-GEADDWQTRFDCAQTEIEFLRKRLLL
CEERLESELSARKELEEKLREARNTYEEVKRNSHQLKRKCRNLTCDLEDTRVLLENQQSR
NHELEKKQKKFDMQLTQAIGKSLFERGLREKLSQENASIRWEFGK---LQSKLEDKEQET
LGLKQKLEMLKSQNLDLR----SLGVEAVDDLQRELWDLKTSTLEQQQIQNEQETTIKKL
EQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXIGHRDFDVEKRLRRDLRRTHALLSDVQLLLSNIEDSQTMVS--KEE
LEKVHIKLEESEAKCADAQNTQKLLGPDLENMHSELENITRNKNLVDEQLYRLQLERADL
L--KRIDEDQEDLNELMKKHKDLIAQSSQDIVQIQELQLSLEETKKEKQSLQE---KLHT
AQSRIEHLEKTTVDRNIVCRQEALICDLENKLEFHKVQIKRFEXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEKH-VEELLAVKLTL
QADLEVSIRRIADMQAALEDVDSC-LTDDXXXXXXXXXXXXXXXXDNQSLPDLSISSQPG
ESIRSWLS------LSPARERSPSQQSANGSGI---LDQRM----HREARDTERRQPT--
------------------------------------------------------------
---------------------------------S--------------------------
---------------------LDRHNLQMSSPTLEKKFPSSSWALSEFIEGFRRKQSEKE
QA--------ALGAEDWPTLPIYQTTGASSLRRSLDSDVP----------EKSSLEPE--
--KFTIGLLRSTSLKCLSSDKSDP-----SLLLQNQFRSCDSLLASIRKI---GRRLSSS
VG-P--RELPSKLRLRRPCIDTPLEEAEDPD--LGKESLVFQNRRFSNLLNEPLEPDLLA
WKLPR--YEQKPRVSFDDYVPAIRKSNSPRIAR------GQDDLMPGTSRYKSEA-SPDR
LFSGSSGAFRENLEPKEDTGHLS---DSSSSSSSAMSYRSADSIKSRPGSLKKDEESDR-
-----------RPEWMDRS--KEVESIMKKYLPK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---ESEEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKESKEARRRKEAALTSPEGETPEVPINQANK--TNN-VPKP-GSQQ
TSQDSPSATQKDADIPGKDPPR-ADDKNSM--PVTSTGGEKPQESGPTGTPAKRTLPFKR
GVRRGDVLLMVAKLDPELAKPEQKTQPRDTP------KDKTPALA-------TDPGGTKK
GATTGTPCGPQTP---I------TEKNSTGGDGDTSQ---GGTKGGKC---QGTEGKG-S
RDPQTKGQKECES-QNTEGQGTRSPAWEAV-NKGQ-----------------------VG
TVEKGGGGPPKKMEKEDGPKGAGAKVR--------PLEPPVPIKKWGVSLGRRSKWDSSQ
SKNR-ESESQRRDEKRGDLQGTA-------------------------------------
--------------------------------------AEPRGQQQ-----EAPGK-MEK
AGGSQKKL---VIPGKCQEQ-PGVT--AETQSPQECCKAPGGMPTEV------AEAARRE
DQPESTAQGAGEPCVHAEEEV---DIEEPQAEGPVESLPKTQVERS-SLQKPMEEEPVLQ
DPG-----RD-SDQ----EDRWYEAQ---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCMDADKTVTEVDEDQVHR------------------------------------
------ANPSELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

TEDLASLVCVNESSVLNTLLQRYQAQLPHTRSGPDLIALQPQKTTV
PSS-----GKVP----RGRQDGLP-AHVTSLAQRAYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVSMAGSVDGRVS-VEKLQAAFTVLQAFGSVSTGHSRRASRFSMVISLDFNA
TGRVTAAQVQTVLLENSRVARQPQGEGNFEVFSQLLAGLDVDLRTELNLHQMSESNAFGM
GVWSQPEDKQKAATAFSQLQGAMELLGISEGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANHAAEALGCDYEELNTATFKHHLRQIIEQMTSGSQRQC---LE-DNDAS
SGLKMTGVE-CVEGMASGLYQELFGAVVYLINRAFSSHHLSMASIMVVDSPGFQNPRHQC
KDRAATFEELCYNYAQERLQLLFYHRTFVSTLER-YQEEGIPVHFDLPESSSGTTVAVVD
HNPS-KAHLPA-GGATEAAGGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKT--VGA--
DGPSVLRICEQPLQCELFHQLGRDPVRYDLTGWLRRAKPNLSALEAPQILQQS--KELQN
LFQARAKLPPVCRAVAGLEGTSQQALHRGRVVRRAFASRVAALKRKAPCAQIKLQMDALI
SLLSRSQLHFIHCLVPTSV-ESKPGQGTPSPPQPGGDQGGANEPPALDIPAMRVQLAGSH
ILEALRLHR---AGYADHMG----LVQFRRRFQALDPQLLKKLDWTSEGLDERKVVEELL
QTLDLEKKAVAVGHSQVFLKAGVVSRLERQREKLVSQNIVLFQAACRGFLSRQECKKLKI
RRLATQCIQKNLTVFLEVKDWPWWRLLASLRPLLSPTLSLEQ-LQAKEEELTLLREKLQK
SEKSRSELRQSTD-LLESKITDLISELADERFKGDVACQALESERAERLQAFREVQELKA
KYQQVQEALGAVQKQLEEAQQKIQLANLEEKHT-GGADEWQMRLDCAQMENDFLRKRLQQ
CEERLDSEMKARTEVEQKLGELQNAYEEAKKTAHQLKRKCHHLTWDLEDTRVLLENQQSR
NHELEKRQKKFDLQLAKALGESMFEKTLREKVSQENSGVRWELGQ---LQQQLEQKEQEA
SKLKQEVEKLQGQKQELLGCA-SVGKQGVASLKEKVWELESSALEQQKVHSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQMEMQLEQEHEEKQVALHE
KRDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKVLTTDLENMHSELETVARSKSVVDEQLYRLQFERADL
L--KRIDEDQEDLNGLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQLRIQYLEQSTVDRAIVSRQEAVICDLENKTEFQKVLMKRFEVLVIRLRNSLIKMGEEL
SQTSKSEAQQRENSQYYQRRLEELKAEMKELMQREEEASRRCMELEKY-VEELAAVRQTL
QVDLETSIRRIADLQAALEDVVSS-DSDTESVLTLA-----------SRDNVSVISSQPE
SSLQSWMSCSL--SLAMDTARAPSQQSVVSSSL---LSPRV----SEEAGDSEKLRP---
------------------------------------------------------------
--ESL--VLKEAWDSPRETSRSGSVSL-----LPVFPQKSYHLEDGEGF-----------
-AVHRETT--PEGPGT-LSSSPTSQSMAKSLLP-RDKLPSPSAALSEFVEELRRKRAQRG
QG-------SSLHLGEGPMLPIFQTTGASLLRR-GRASSDEGGLSLRTG-AKSPLQAEGN
PRVPTAGLSRSTSLKCISSESTEN-ITLPPDKQKTRFGSCESLLESGPST---RR-----
----KDPLLSPTLQPRRRCLESSVDEAVCLD--LGKEPLVFQNRQFSHLMEETLDSDPFS
WKLPSLNYRRQTKVDFDDFLPAIRKPSDPLPEA---AKDGKEATKHPNVHFEMEE-ADHS
SLSGIKTILKKNPESREDPAHLS---DSSSSSSSIISFKSTDSIKSSPRVPRLQGDGGER
V-SPEHRE-PGT----GR-S-DDVESIMRKYLQQ-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRRKEALLASPEQETPEVSIGQPNS-KAHS-GTKS-GSQH
TSGDSQSTSPQGTSIPGKDSQG-SGSANPE--LMTRVSGEKPQELAPSGTPARKVLPFKK
GVRRGDVLLMVAKLDPEAAKPEQRTQARDVP------TCKTSPAA-------TDPGGTKK
GETPGTPSGPQAS---TEDLASKPEKTPTGGHGDPGQ----GTKGDKG---QGTVGKG-S
GGLQTKGSKGGES-KGKEEQRTRLQSQGAG-DGGQ-----------------------QR
TVEKEGGDPPSKMEKRNV-----SKDVG---AEGKRVGLQVQGRKWGGSLSRKSKWDSPQ
SKKDRESEPPSTTGRTGKPQAKT--------------------EERGKVQGKAGQVGEAP
RALEEAVELGKASE--------------------------------------A--SKSEE
AEQPRRKA---V----------G-S-GGAGSQAEKGCKAPKEVAAER----VPPAATEPQ
SRPESSAQRAEEQCTTEEGAA---GAWPPRQEGSAEPSQETQAEGP-PGQMQTQEGPALQ
DRGRGDHS---GDLDQAREDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTVTEVDEERIHR------------------------------------
------ANPPEFDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

DDLASLISVNESSVLNTLLQRARAQLLHTRAGPDLIVLQPQGPAA
PSA-----GKVP----RGRRDGLP-AHISSLAQRAYWAMLSQRRDQSIIALGRSGAGKTI
CCEQALEHLVGMAGSVDGKVS-VEKIRATFTILRAFGSAHTGHSCSATRLAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARPPEGEGTFPIFSQMLAGLDLDLRTELRLYQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMETLGITEGERRAIWRVLAVIYHLGAAGACK------V
GRKQFMRFEWANHAAEVLGCEYEELNTATFKHHLRQIIEQVTSGPSRWG---FK-DEEPS
SGFKMTGTE-CVEGMASGLYQELFAAVVSLINRSFSSQHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYVHERLQLLFYQRTFVSVLER-YKEEGIPVPCDLPESSPGTTVAVMD
QNPS-QVHLPA-GGGTEDARGLFWVLDEEVQIEGSHDSMVLER-LRAAFEKKGAGAK---
-GTSALRTCEQPLQCEIFHQLGQDPVRYDLTGWLHRAKPNLSALGAPQVLQQSRREELRS
LFQGRAKLPPVCQAVAGLEGTSQQALHRSHVVKRTFASSLASARRRAPCSQIKLQMDALI
SLVRRSQLHFIHCLVPTPAVD-KGEQGSLPPPLP-GDQPGAGKPLAPDIPALRVQLAGSH
ILEALRLHR---AGYADHMG----LAQFRRRFQVLDPVLLKKLASAPEGIDERKAVEELL
QTLDLEKKVVAMGHSQVFLKAGVVSRLEKQREKLVSRNIVLFQAVCKGFLSRQEFKKLKI
RRLAAQCIQKNVAAFLVVKDWPWWQLFGSLRPLLSATIGNEQ-LQAKEEELTMLRQKLEK
SEKSRNELRQSAD-LLESKIADLTTELADERFKGDVACQVLENERAERLQASREIQELRS
KYEQVQKNFGEVEKQLEEAQQKIQLNDLERKPT-GAADEWQMRLDCAQMENEFLRKRLQQ
CEERLESELTSRKELEQKLGELQSAYEEAKKTAHQLKKKCHHLTWDLEDTRVLLENQQSR
NHELEKKQKKFDMQLARALGESLFERSLREKVSQESNSVRWELGR---LQEQLEQKEQET
LRLKQEVEMLQEHKQELLGSP-SLGEKGLAGLKERLWKLESSAREHEKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQTVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLATMEDSKTSVS--KEE
LEKVHSQLEQSEAKCEDALKTQKALTLDLENMHSELENMTRSKTLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQVQLEDAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAAICDLENKTEFQKVQIKRLEVLVIRLRDSLIKMGEEL
SRAVASESQQRESSQYYQRRLEELKADMEELAQRETEASRRCMELEKY-VEELGTVRQTL
QTDLETSIRRIADLQAALEEVVSS-DSDSESVQTAVDCGN---GGRKEMDNVSIISSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSATSSCL---RSSR--------------------
------------------------------------------------------------
VKAEAGDAESRTWNS--HGKASREGSA---SPCSTRQQKSCHFGGGEGF-----------
-GVQRKPM---ERSGA-LSSPVASQSPNTSPLP-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRASSDEGDLSLKLQ-TKSPLGVEGA
PG-TTAGLLRSTSLKCISSGGAEG-TSLPPERLKTRFSSCEALLESGPSV---RKKMSSP
TA-LRDTLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPCS
WTLPSLSYGRRARVDFDDFLPAIRKPESPTSLARA-AKDEHKGSKHPGVHFGMEE-ADRS
FLSGIKTILKRSTQPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPRPPRLEGDGGEQ
V-SPEHRE-PGT----ERK-EEDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKE--IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRKKQAALASPEQEXXXXXXXXXXX-XXXX-XXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXX---XXXXXXXXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX---XXXXXXXXXX------XXXXXXXX-------XXXXXXXX
XXXXXXXXXXXXX---XXXXX--XXXXXXXXXXXXXX--XXXXXXXXX---XXXXXXX-X
XXXXXXXXXXXXX-XXXXXXX-------XX-XXXX-----------------------XX
XXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX----X---------------XXXXXXXXX-XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXKAGEPQA-----------------------EIQK
GRQPLSK---------C-----REA-GDSRDKREKGCAVSKEEDVRE----KSSVLAVRE
RRPDARGHKEQGLSPRAVTEA---KALEVQLERPG-PGLQTPAERP-QTQEENQEGPCLR
ERDTEGHRGD---SDQVPDDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCIDADKTITEVDEEHIHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

VEDLATLISVNESSVLNTLLHRCQARLLHTYAGPDLIVLQPRGPME
PSA-----GKMP----RGRWDGLP-AHIGSLAQRTYWALLSQRRDQSIVALGRSGAGKTT
CCEQVLEHLVRLAGSVDHIVT-VEKIRAVFTILRAFGCVSVGHSRSATRFTMVMSLDFSA
TGRITAAQLQTMLLEKSRVARQPEGEGNFEVFSQMLAGLDLDLXXXXXXXXXXXXXXXXX
XXXXXPEDKQKAAAAFAQLQGALETLGISENEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANRAAEVLGCEYEELNRATFKHHLQQIIDQVVSGSSRRS---RE-DEETS
SGLKMTGVE-CVEGMASGLYQELFATVVSLINRSFSSRHLSMASIMVVDSPGFQNPRHQA
KERAATFEELCHNYTHEHLQLLFYQQTFVSTLER-YREXXXXXXXXXXXXXXXXXX-XXX
XXXXXXVCLPA-GGHDGDTKGLFWILDEEVRVEGSSDSVVLKR-LCGTFEKKGAGPEXXX
XXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEELRS
LFQPRAKLPPICQAVAGLEGTSQQALQRICAVRKTFASSLAAVKRKAVCAQIKLQMDALT
GLIRRSQLHFIHCLVPNPAVESRGGQGSPAPPQPGGDKPRASEPLAVDIPALRVQLAGSH
ILEALRLHR---TGYADHMG----LTQFRRRFQVLDPPLLKSLMSTSEGIDERKAVEDLL
QTLDLEKKAVAMGHSQVFL

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KAGMVSRLEKQREKLV

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

AQSIVLFQAACKGFLSRQEF

ENSGT00920000149027_1_Linker_4_5 (1676, 1872)

RKRKI
HRLAAQCIQKNVAVFLAVKDWPWWRLLGSLRPLLSATIGEEQ-LRAKEXXXXXXXXXXXX
XXXXXXXLRQ-AD-LLESKIADLTTELADEHFKGDVACQALETERAERLRAFREVQELKS
KYEQVQKNLGEVEKQLGEAQRKIQLNDLGRSHT-GGADEWQVHLDCAQVENEFLRKRLQQ
CEERLNSEMTS

PF01576 // ENSGT00920000149027_1_Domain_5 (1872, 1936)

RKDLEQKLGELQGAYEEAKKMAHQLKRKCHRLTCDLEDTRVLLENQQSR
NHELEKKQKKFDVQLAQALGASVFEKSLRERLTQENTSIRLELGK---LQQQLEXXXXXX
XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXX
XXXXXXXLEQSEAKCEDALKTQKALTADLESMHSELENMTRNKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGQIQEMQLQLEEANKEKHKLQE---QLQV
AQMHIEYLEQSTVDRAIVSKQEAIICDLENKTEFQKVQIKRFEXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTEXXXXXXXXXX---XXXXXXDNVSTISSQPE
SSLQSWLSCTL--SLATDTVRSHSRQSVISGHT---LSPRI----KEEAGDADRARAAS-
------------------------------------------------------------
-------ALSGG-----HCKT-----PGSQSPFSSHRQKFRLLGDGEGL-----------
-GTQRKSR---EKLDA-LSPSPSSQSRETSPLS-GAKLPSPSAALSEFVEGLRRKRAQRG
QG-------SPLGLEDWPTLPIYQTTGASTLRR-GRARSDEGDLSLRLG-AKSPLETEGT
-----VGLPRSTSLKCISSDHAES-TTPLPEKLKTRFSSCESLIESGSSL---GRRLSSS
AT-PKDGLLSPTL-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALASPEPEIPEISISQPNS-KSSS-GTRS-GSQQ
ISQDDQSSSPGSSDILGKESEG-SCSPDPE--QMTSINGEKAQELGSSATPTKKTVPFKR
GVRRGDVLLMVAKLDPDSAKPEK-THPHDTP------PCKTPPPA-------TDTGKEKK
GETSRTPCGSQAS---TEILASKAEKTRTGGLGDPGQGTVALKKGEKG---QSIVGKG-L
GTPKTTELKEAEP-QGKDRQGTRPQAQGPG-EGVR-----------------------PG
KAEKEGAEPTNTVEKGNVSKDVGSEGK--------HVRPQIPERKWGGFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----M---------------EKTSQVQGK---LGDDL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------DKEN
TGQPQGK--------------SGNAG-EARSQTEKGCEAPKEVSTMV----ESPSASGKG
GWPGSRGQEGEEPCSRAGDGA---GALETELEGPSQPPLEKDAERP-RIQKENQDGPAPQ
EEGKGGQSRD-S--DQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKTITEVDEEHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1521)

VEDLASLISVNESSVLNTLLQRYKAQLPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRRDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRTELNLHQMADSSSFGM
GVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWG---LE-DEETS
SGLKMTGVD-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYTHERLQLLFYQRTFVSTLQR-YQEEGVPVQFDLPDPSPGTTVAVVD
QNPS-QVRLPA-GGGAQDARGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SVIKRSQLHFIHCLVPNPVVESRSGQESPTPPQPGRDKPGAGGPLALDIPALRVQLAGFH
ILEALRLHR---TGYADHMG----LTHFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAARCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTDLADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQQVEMLWDHKRELLGSP-SLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDCEDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSATSSHI---LSPRI----NEEAGDTERTQS---
------------------------------------------------------------
--AL---ALSRARSTDVRSKTSGDKPV---SPHFVRRQKDYHFGDGEGL-----------
-AVQRKST---ERLEP-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSL
TT-PRDTLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSRRSSIHFETEE-ANRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDSGER
T-SPERRE-PGT----ERK-DDDVASIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQLALAAPERETPEISISEPNS-KSSS-GTRS-GSQQ
ISQDNQSSSPGSSDILSKESEG-TGSPNPE--RMTSINGEKAQELGSTATPAKKTLPFKR
GMRRGDVLLMVAKLDLDSAKPER-THPHDTS------PCKTPPPV-------TDTGKERK
GETSRAPCGPQAS---TEILAPKAEKTRTGGLGDAGQGTVALKKGEKG---QSIVGKG-G
GTPKTKELKEAEP-QGKDRQGTRPQAQGPS-EGVR-----------------------PG
KAEKEGGEPTSPVEKENVSKNVGSEGK--------HIGPHIPGRKWGGFLGRRSKWDGPQ
NKKDKEGVLLSKAEKTGEPQTQ-----T---------------EKKSQMQGE---LGDDL
RM-GEKAGELRSMT-----------GKAGESWD-----------------------KKEK
IGQPQGK--------------SGKAG-EARSQTEKGCEAPKEVSTMV----ESPVAAGKG
GWSGRSGQEAEGPCSREDVGS---GALETELEGPSQPALEKDAERP-RIQKENQDGPAPQ
EAGKGGQSRN-S--EQAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
AGRVRLCIDADKSITEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1640)

EDLASLISVNESSVLNTLLQRYRAQRPHTCTGPDLIVLQPRGPSV
PSA-----GKVP----KGRWDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTA
CCEQVLEHLVGMAGSMDGKVS-VEKIRATFTVLWAFGSVSMAHSCSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRMELNLHQMADSSSFGM
GMWSKPEDKQKAAAAFAQLQGAMETLGISESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSQRD---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLQR-YREEGVPVQFDLPDLSPGTTVAAVD
HNPS-QVRLPA-GGGAQDAKGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLQQSKREELRS
LFQSRAKLPPVCQAVAGLEGTSQQALQRNRMVRRTFASSLAAVRRKAPCSQIKLQMDALT
SMIKRSRLHFIHCLVLNPVVESRSEQESPTPPQPGRDKPGADAPLALDIPALRVQLAGFH
ILEALRLHR---TGYADNMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKKAVALGHSQVFLKAGVISRLERQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAMFLAVKDWPWWQLLGSLRPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPA-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
LQLKQEVEMLQDHKWELLGSP-SLGENCIAGLKERLWKLESSALEQQKVQSQQENTIKQL
EQLRQRFELEIERMKQIHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKTDL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELGAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNVSILSSQPE
GSLQSWLSCTL--SMATDTMRTPSRQSATSSRI---LSPRI----NEEAGDAERTQS---
------------------------------------------------------------
--A-----LSRAWSTDVRSKTSGDKPV---SPHFVRRQKYCHFGDGEGL-----------
-AVQRKSA---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYLTTGASTLRR-GRAGSDKGNLSLRV-GAKSPLEIEGA
A----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRPSM---GRKLSSP
TT-PRDMLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQMPTSLAGA-AKDGQDGSQRSSVHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIQRLAGDGGEG
T-SPEHRE-PGA----GRK-DDDVTSIMKKYLQK-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------DVWYETE---QVW--YIHNDGFTLAT---ELKPDVGTPELA
AGKVRIRIDEENRVLEVDEENIHR------------------------------------
------TNPSKFDY

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1640)

AEDLTTLISLNESSVINTLRHRYQSQLIHTSAGPNLIVLKPSSPVA
NFST--KASHVF----QGKKDSMP-PHICSVAQKAYWNMLTQRQDQTILPLGRSGSGKTT
CCQSALEYLAAAAGTVDNRVTDLEKIQAMFTVLKSFGCVTTRECSNSTRFSMVMSLDFNA
AGRITAGHLQTMFLERIRVAQQPQGESNFNVFTQLLGGAETDLRSELYLHQMADNHSFGM
APCVKPEEKQKASAAFVQLQSAMEVLGFTAIEQKAIWHVLAGIYHLGAAGACRESL--LV
GRKQFMRFEWANNAANVLGCDCEELSTSVFKHHLKQIIQQVTSGSRGGN---QEDDTNCA
TGPKMTGVE-CVEGMAAGLYEELFAAIVTLINRCLSSTLLTLASIMVVDITGFQNPRHQK
LERAATFEELCHNYVQERLQCLFYSRTFLHTLER-FQEENIEVAFDPPQDIPFVTVSVID
QISS-QINVQS-SNQMEEKKGLLWILDEEVLIQGSTDSNVLDR-LCSYFEMKGEDN----
F-----LFFSNCYHFEILHQLGKDPVRYDVTNWINKAKLNQSAENAIQVLQQSRLDFVKD
LFAPRAKFPLICRSVSGMEGKSQQALQRISCVRKTFASSFAAIRRRSVCGQIKLQMDALI
NLLKRSQIHFVHCMVPRLGMDGSECKI--HP--LCKGTAGDPINAVIDVPSVRIQLASAQ
LLDAMRLCR---IGYPDRIG----FTEFRLRFQVLASEAMKKYNSTYEPVDERKAVEELF
QLLDLEKKSVLMGRSQVFM

ENSGT00920000149027_1_Linker_1_4 (1640, 1656)

KSGVLPRLEKQREKTI

PF00612 // ENSGT00920000149027_1_Domain_4 (1656, 1676)

SQRMVLLQAACRGFLCRQKYKNLKI
QLIALKCLQKNIRKFYLVRHWPWWKIICHFRPSLSVNIDEEK-FKAKQEEITVLSLKFKK
SEKSRNELRQNVD-LLESKITDLTTELSDERFKGEVTCQVLEVERGERLRASREIKEMQA
KYEQMQKNLDSVSKQLEDAQQQIQLRELNAGSS-GRADEWQIRFDCAQTEIDFLRKRVTQ
FEERLESEKSYRKDLEQKLSQLQGAYENAKRAAQQATRKCKHLTSDLEDTRVLMENQQIR
NHDLEKRQRKFDMQLAQAIGEAAFEKSLREKVTQENTSCRWEVGK---LRQSLEKKELET
ANLTRQLEVLGNRVKELSTSS-GLDNNSVASLKTKVWELETSVAEQNQQLTEQANAIQLL
EQTRLRFEMEIERMKQIHLKELEDKEEELEDIRQSCQRRLRQFEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCEQIGHRDFDVEKRLRRDLKRTHALLADLQLLLASMGDSGPSVD--RGE
LEKVHIQLEESEAKCADALKCQKSLSMELDSLHMELENLSRNKNMADEQLFQLQREKTEL
L--KRIDEDQEDLNELMKKHKALIAQSANDITQIRDLQTKLEDTKKEKQILQEKPEQLQV
AQSRIDYLEHSMVERSIVSRQEAVICDLESKLEFQRAQIKRFEVLILRLRDSMIKMGEEL
ENAADSEAREKENAKYYQIRMEEMKVEMNELLQREMEACRRRVEL---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

------------------------------------------------------------
---------------------MAISSRLALWEQK---IREEDKSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARLRKEAALASPEREIPEVSAGQPSA-G-----TKP-GS--
--QNAQSGSPPSADVLGRKDEE-PGTKDPV--LM-TINGEKPQESGPSGTPAKKILPFKR
GVRRGDVLLMVAKLDPDSAKPEQRTQPRDAP------TSKTPPPA-------TDPGGGKK
GDTPGTSRGPQAS---TTDTPPKAEKTQTGGLGDPAPGTVLPMKGEQD---QGTVGKG-G
EAPQTKGVKRGEL-QGKEGRGKLQGKEGLG-DGGQ-----------------------PG
AVEKGAGDPPNKGAKGSLSKDVAGEGK--------WAGAQAPVRRWGSSLGRRGKWDSPQ
RKKDKEGPLLSEADKTEEPQTK-----V---------------EKTGKVP---GRAGEAP
RA-VDKAGE-RSRT-----------GKAGEPRG-----------------------KMEK
MGPPQ---------------------------------APKEVDARG----DTPTTAGKE
DQPESRGQKAEEPRPRAGKGAGAAGALEMGLGGPGQPALDT----------------ESQ
EGHGGGQSRV-S--EQAPEDRWYEAE---KVW--LVQKDGFTLAT---VLKPDEGTADLP
AGRVRLCVDADSSVTEVDEEHVHR------------------------------------
------ANPPELDQA

PF00063 // ENSGT00920000149027_1_Domain_1 (856, 1518)

EDLASLVSVNESSVLNTLLHRYQAQLPHTLAGPDLIFLQPQGLMA
PSA-----SKTP----VHHRDGLP-AHISSLAQRAYWALLSQRRDQSIVTLGRSGAGKTT
CCEQVLEHLVGMAGSVDGSVS-VEKIRAAFTVLRAFGSVSTGHSRSATRFAMVMSLDFNA
TGRVTAAQLQTMLLEKSRVARQPEGEGNFEVFSQMLAGLDLDLRTDLYLHQMADSNSFGM
GLWPKPEDKQRAAAAFAQLQGAMETLGISDGEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMRFEWASHAAEALGCEYEELNTATFKHHLRQIIAQVTSGPSRRS---LE-DEEAS
SGLKMTGVE-CVEGMASGLYQEVFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSALER-FREEDVPVQFDLPESSPGTTVAVVD
QTPS-QVRLPA-GGGAEDARGLFWILDEEVRVEGSQDSVVLER-LCAASEKHGAGA----
EGASALRTCEQPLQCEIAHQLGHDPVRYDLTGWLHRAKPNLSALDAPQVLQHSNREELRT
LFQSRAKLSPVCRAVAGLEGTSQQAQQRSCVVRRTFASSLAAVKRKAPCSQIKLQMDALI
SVIRRSELHFIHCLVPS

ENSGT00920000149027_1_Linker_1_3 (1518, 1546)

TAVESRGGQGSPTPPQPGGDKPEAGRSL

PF00063 // ENSGT00920000149027_1_Domain_3 (1546, 1640)

PLDIPALRVQLAGSY
ILEALRLHR---TGYADHMG----LTQFRRRFQVLDPVLAKELISAPEGVDERKAVAQLL
QTLDLEKKAVAVGHSQVFLKAGVVSRLEKQREKLVSQSIVLFQAACRGFLSRQGFKKLKI
HRLAARCIQKNVAVFLTVRDWPWWRLLGSLRPLLSATIGEEQ-LRTKEAELTALRQKLEK
SEKSRNELRMNAD-LLESKIAELTTELADERFKGDVACQVLESERAERLRASREVQELKS
KYEQVQKNLGEVEKRLEEAQQKIQLNDLERSHT-GGADEWQMLLDCAQMENEFLRKRLQQ
SEERLESELASRNELEQKLAELQRAYEGAQRTAQQLKRRCHLLTCDLEDTRFLLENQQSR
NHDLEKKQKKFDAQLAQALGECVFEKGLREKVAQENTSVRCELGK---LQQLLKQKEQES
LQLKQEVEMLQAQKQELLRSP-SLGENCIAGLKERLWKLESSALEHEKVQNQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDKEEELEDVRQSCQRRLRQLEMQLEQEYEEKQMALHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVQSQLEQSEAKCEDALKTQKALTADLENMHSELESMTRSKSLVDEQLYRLQFERADL
L--KRIDEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKNKLQE---QALL
ALMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAAAAESQQRENSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAIRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVNCGGG--SSRKEIDDVSTLSSQPG
ASLQSWLSCTL--SLATDTARTPSRQSAVSSRT---LSPRT----HEEAGD---------
------------------------------------------------------------
------------GARDVRSRTSGDKAA---SPLSRRRGTYGHFGDGEEC-----------
-GVQRKTP---ERPGA-PP-SPSSRSGDMSPLP-RDKLPSPSAALSEFVEGLRRQRAQRG
RG-------SPLGLEDWPTLPIYQTTGASTLRR-ARAGSDEGALALRAG-AGS------A
LD-ASAGLPRSTSLKCISSQSVGS-PSPPPEKLKTRFSSCESLLESGPSS---QRTPSSQ
AAARRDPLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMGDPLGSDPFS
WKVPSLNYERKTKVDFDDFLPAIRKPETPTSLARG-AKDGRDSSQHSSVRFETEE-ADRG
FVPGIGTVLKRSPESREDLAHLS---DSSSSSSSIMSFKSADSVKSRPSAPRLEGDGGEQ
A-SPENRE-PGT----GRK-EEAVESIMRKYLRK-

------------------------------------------------------------
---------------------MAISSRLALWEQKE-TIREEDRSPPPSSPPPLFSVIPGG
FIRQLVR----ETEKESKEARRRKQAVLASPEQETPEISTSQPNS------GTKS-GSQH
ISQDNQSSSPQSSDILGKKSEG-AGTMDPE--LMTSINGEKPQESGPSVTPARKSLPFKR
GIRGGDVLLMVAKLDPDSAKPEQRTQPRDGP------ACKTPAP---------DPGGEKE
QETPGTPCGPQAG---TQDAALKAELTQTGDLGNPGT--VLLTKGEKD---QGTMGKG-G
GAPQTKGTKGGEP-QGREGLG----------EGGQ-----------------------LG
AAEKGRGDPPKKGAKWNFSKVAAGEGK--------WAGAQAQVRKWGGSLGRRSKWDGPQ
SKKDKEGVLLSKADKTDGPQTEV--------------------EKPGTVQGD---VGEAP
GV-MEKAGKPRSMA-----------GKAGEPQG-----------------------KTKP
VGQPQSE--------------SGEA-GKAGSKTEKDSEAPKEVDAHG----ETPVTAGKE
DQPERRGRKAEDACARASDGA---GALEVEPQGPGQPALENRVERPQS--QESQEGPALQ
EGSRGGQSGVSGQXXXXXXXXXX-----------XXXXXXXXXXXXXTVLKPDEGTADLP
AGRVRLCIDADKSITEVDEDHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1635)

AEDLASLVSVNESSVLNTLLHRRRARLLHTCAGPDLIVLQPQGPTA
PSA-----AKVP----RSCQDGLP-THVVSLAQRAYWALLSQQRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTVLRAFGSVSTGHSRCATRFSMVMSLDFNA
TGRVTAAQLQTMLLEKSHVARQLEGEGNFEVFSQMLAGLDLDLRTELYLHQLADSSSFGM
GVWPKPEDKQRAAAAFAQLQGAMETLGILESEQRAIWRVLAAIYHLGAAGACK------V
GRKQFMHFESASHAAEALGCEYEELNTATFKHHLRQIIERMTSGPSRRG---QE-DEGDS
SGLKMTGVE-CVEGMASGLYQEVFAAVVSLVNRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRAATFEELCHNYAHERLQLLFYQRTFVSTLER-FREXXXXXXXXXXXXXXXXXX-XXX
XXXXXXVRLPA-GGGAEDARGLFWLLDEEVRVEGSGDSVVLER-LCAAFEKKGA------
EGTSALRTCEQPLQCEIAHQLGHDPVRYDLTGWLHRAKPNLSALDAPQILQQSKREELRG
LFQSRAKLSPVCRAVAGLEGTSQQAQQRSSTVRRAFASSLAAVKRKAPCSQIKLQMXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXYADHMG----LTQFR-RFQVLDPLLMKKLKSAPERVDEKKAVAELL
QTLDLEKKTVAMGHSQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXAELTALRQKLEK
SERSRNDLRQNTD-LLESKIAELTAELAEERFKGDVACHVLESERAERLRASREVQELKS
KYEQVQKNLGEVEKQLEEAQQKIRLNDLERSRT-GGADEWQMRFDCAQMENEFLRKRLQQ
SEERLDSELASRNELEQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXFDMQLAQALGESVFEKGLREKVAQENTSVRCELGK---LQQQLKGKEQDT
LQLMQEVEMLQQKH--ELLSP-SLAENCIAGLKERLWKLESSALEQEKIHTQQ-ETIKQL
EQLRQRFELEIERMKQMHQKDREDTEEEMEDIRQSCQKRXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDSKTSVS--KEE
LEKVQSQLQQSEAKCEDALKTQKALTADLENMHSELESMTRSKSLVDQQLYRLQFERADL
L--KHIEEDQDDLNDLMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKQKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTGFQKVQIKRFEVLVVRLRDSLMKMGEEL
SQAATAESQQRENSQYYQRRLEELKADMEELVQREVEASQRCMELXXXXXXXXX-XXXXX
XXXXXXXXXXXXDLQAALEEVVSS-DSDTESVQTAVDCSG---SGRKETDNVSILSSQPE
GSLQSWLSCTL--SLATDTVRTPSRQSAISSCI---LSPRI--QEAAS--D---------
------------------------------------------------------------
------------GARDTHSRTWGDKAA---SPLSLRRGNYGHLGDGEEC-----------
-GVQRKPP---ERSRA--SSSPSSWSGDVSPRP-RDKLPSPSAALSEFVEGLRRKRAQRG
RG-------SPLGLEDWPTLPIYQTTGASTLRR-ARTGSDEGALALRAR-AESPLD----
----VGGLLRSTSLKCISSKSVGG-PSPPPEKLKTRFSSCESLLESGPGS---RRTPSSP
TA-LRRSFLSPTLRPRRRCLESSLEDAGCPD--LGKEPLVFQNRQFAHLVGDPLGSDPFS
WKVPSITYERKTQVGFDDFLPAIRKPETPTSLARA-AKDGQDSSQRPSVHFEMEE-ADGG
FVSGITTVLKKSLESKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPRIPRLEGDSGER
T-SPEIRE-PGT----GRK-EEDVESIMKKYLQK-

------------------------------------------------------------
---------------------MAISSRLALWEQKESDIREEDKIPPPSSPPPLFSVIPGG
FIKQLVR----ETEKEAKEARQRKQSALASPERETPEISISQPNS-KSSS-GIRS-GSQQ
ISQDNQSSSPGSSDILGKESEG-SGSPDPE--RMTSINGEKAQELGSSVTPAKKTLPFKR
GVRRGDVLLMVAKLDPDSAKPER-THPHDTP------PCKTPPPA-------TDTGKEKK
GETSRTPCGPQAS---TEILAPKAEKTRTGGLGDTGQGTVALKKGEKG---QSIVGKG-S
GTPKTTELKEAEP-QGKDRQGTRPQAQWPS------------------------------
--EKEGAEPTYTVEKGNVSNDVGSEGK---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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---------------HAPEDRWYEAE---KVW--LAQKDGFTLATV---LKPDEGTADLP
TGRVRLCIDADKTITEVDEEHVHR------------------------------------
------ANPPELDQ

PF00063 // ENSGT00920000149027_1_Domain_0 (855, 1372)

VEDLASLISVNESSVLNTLLQRYRAQLPHTCSGPDLIVLQPRGPSV
PSA-----GKVP----KGCRDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTT
CCEQVLEHLVGMAGSVDGRVS-VEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNA
TGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRAELNLHQMAESSSFGM
GVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGVAGACK------V
GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRRG---LE-DEETS
SGLKMTGVE-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQG
KDRATTFEELCHNYTHERLQLLFYQRTFVSTLQR-YQEEGVPVQFDLPDPSPGATVAVVD
QNPS-QVRLPA-GGGVQDARGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----EGKEAR-------------------------GW-GWAKPNLSALDAPQVLQQSKREELRSLFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMVSGHRLMGFRELGWVFS-------------------------------------------SGLCALLLPAPTS---LGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELLETLDLEKNAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGNEQ-LRAKEEELTTLRRKLEKSEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-GGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEASQLKQQVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEELEKVHSQEKRE--KCETE--------VYLSRMHSELENMTRNKSLVDEQLYRLQFEKADLL--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTLQTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNISILSSQPEGSLQSWLSCTL--SLATDTMRTPSRQSATSSHI---LSPRI----NQEAGDTERTQS-

PF00063 // ENSGT00920000149027_1_Domain_1 (855, 1372)

VEDLASLISVNESSVLNTLLQRYRAQLPHTCSGPDLIVLQPRGPSVPSA-----GKVP----KGCRDGLP-AHIGSMAQRAYWALLNQRRDQSIVALGRSGAGKTTCCEQVLEHLVGMAGSVDGRVS-VEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFQVFSQMLAGLDLDLRAELNLHQMAESSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGVAGACK------VGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRRG---LE-DEETSSGLKMTGVE-CVEGMASGLYQELFVAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRATTFEELCHNYTHERLQLLFYQRTFVSTLQR-YQEEGVPVQFDLPDPSPGATVAVVDQNPS-QVRLPA-GGGVQDARGLFWVLDEEVRVEGSSDSVVLER-LCAAFEKKGAGT----
EGKEAR-------------------------GW-GWAKPNLSALDAPQVLQQSKREELRS
LFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMVSGH
RLMGFRELGWVFS-------------------------------------------SGLC
ALLLPAPTS---LGYADHMG----LTHFRRQFQVLDPPLLKKLMSTSEGIDERKAVEELL
ETLDLEKNAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKI
RRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGNEQ-LRAKEEELTTLRRKLEK
SEKLRNELRQNTD-LLESKIADLTTELADERFKGDVACQVLESERAERLQAFREVQELKS
KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-GGADEWQMRFDCAQMENEFLRKRLQQ
CEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTRVLLENQQSR
NHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ---LQQQLKQKEQEA
SQLKQQVEMLQDHKRELLGSP-SLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQL
EQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLRQLEMQLEQEYEEKQMVLHE
KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVS--KEE
LEKVHSQEKRE--KCETE--------VYLSRMHSELENMTRNKSLVDEQLYRLQFEKADL
L--KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE---QLQV
AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEEL
SQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKY-VEELAAVRQTL
QTDLETSIRRIADLQAALEEVASS-DSDTESVQTAVDCGS---SGRKEMDNISILSSQPE
GSLQSWLSCTL--SLATDTMRTPSRQSATSSHI---LSPRI----NQEAGDTERTQS---
------------------------------------------------------------
--AL---ALSRARSTDVRSKTLGDKPV---SPHFVCRQKYCHFGDGEGL-----------
-AVQRKST---ERLEA-ASSPLASRSTNTSPLS-REKLPSPSAALSEFVEGLRRKRAQRG
QG-------STLGLEDWPTLPIYQTTGASTLRR-GRAGSDEGNLSLRV-GAKSPLEIEGA
T----GGLLRSTSLKCISSDGVGG-TTLLPEKAKTRFSSCESLLESRLSM---GRKLSSP
TT-PRDTLLSPTLRPRRRCLESSVDDAGCPD--LGKEPLVFQNRQFAHLMEEPLGSDPFS
WKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGA-AKGGQDGSQHSSIHFETEE-ADRS
FLSGIKTILKKSPEPKEDPAHLS---DSSSSSSSIVSFKSADSIKSRPGIPRLAGDGGER
T-SPEHRE-PGT----GRK-DDDVASIMKKYLQK-