ENSGT00920000148995_2 : Linker Region Query Results

MQPLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSATGSLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDVSQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRKLAGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSSEESPAAQ
ASECLHPCRVSERS-ME------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPHWSTS-----------------THSHCSLLVNRALSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VHSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-SMNTFTLFLRI
KFFVSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTVLRVQVEVSEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGS EQPSHVLFD--
HDKFVQTANL-------------------------SPAH--QVQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAVGGM--LSTSLDNFNVDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSM----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVH VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVKMIQNSPDNIELI ISQSKGVCGNNPDEEKN-NTANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSYTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSLPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANASMGDEHMAVSLVTALPGRPLSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPEAREGLGL
RPE-SSQKAIRAAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERE--
------ASTLETSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EGDVYHPCG
AP----------------SPTSEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTILLPQFCSWG--TVPE-SLPPEES
PESGSKWEDLEEPVDLE--YGALR-------S--L---S----FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDTGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSATGSLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRKLAGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
ASECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPDPHWSTS-----------------THSHCSLLVNRALSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--PSQKGFLQRRSK---FSRP---EFILLAGE
APTTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQRLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-STNTFTLFLRI
KFFVGHYGM LQHSLTRHQFYLQLRKDILEERLYCNEELLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEISEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNNRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAVGGM--LSTSLDNFKVDGSKEAGA-EGIGH-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPAQSM----------------------
---------------------------------H--AGSQSNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSRTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KD--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCISVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSTDKEFTRATCTDSCTSPILDQEDSWRDSASPEAGEGLGL
RPE-SSQKDIRAAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIMRLGRYSF--------SSSLTRPSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--------------VTLAEVLWAKGSPLEEEDIWALLYLATVQLLEDLHKVGF---SDPA
IRVLCPWSVLLSAEGNLSFQNNAPQTEAIPFSAPELLHRQNKNQ-CIGLTKMLVYSLGMT
LYWSADYQVPPNQSLQLS-DQLHSLLLTLCEDLPHKRLSPESILEACEAHQKESSSLP--
VNVYIKKMVQFVVGSVSEVERVATED------STASQLHRSHVIRRRLHEKILDAS-PPS
SQMNLHRGPANQITFR------NKGTNAE--IHCGSH-QSGSFPN-----DLNH--SVGG
------NSNTSRKGTCTFIFKLESELGMPRQDVYTAQKQKAPVAQMSLTSPK--SRLIIL
LPPSMSLHEKQSPFSCCGRDSGNMAKKKKGAYCFIKSLPRDISQRKRIYPGENKTTT---
---------KNH------------------TTCRVASHPSVLRMSKVGVLVQLLLILSSC
EEKLTY---HSSIYHLYHYVRTV-----LPLN---FSF--HIFRHSNADPFSSSR-----
-VIP------GRVTQTHRSWD--PTLSESRTQSSYKLFI---NRVKLASVCRAMAFTQRR
LSCQVWHPAGRVTGSTFSVSTKDY--TAAAASQKCLFQRKEKIFLFSGP---EFIILSSE
PPVTLQLPGSIVLSQTKKGKS-------YLSQRDLNVILLNGQCLEVQCDVKSKARDVFN
TVVAYANLVEHFYFGLAYLKGKEFFFLDDDTKLYKVAPEGWNDQPKKKTSIINFTLFLRI
KFFVNHFNIIQHGLTRHQFYLQLRKDILEERLYCSDETALKLGALA-------LQAELGN
YASE-----V--HGKSYFRVEDYIPASRIEKMTLAYVQRELAKLHRMNRSLFEDEAELEF
LKVTQQLPEYGVLFHRVSQEKKGAGG-DIILGICAKGIIVYEVKNHTRIASLRFQWRETE
RISAHRKKFMIESSFSGKKHTFITDTAKTCKYLLDLCSAQHKFNAQMNSRQLRQTSSDSF
LHTL-NFYNMQFIKILRFKLYRAVHFICLCGKRVQKARQKLLKKHEHLALIQRLSRSE--
-----NVLYGA----NLENLSAGM--MSKSCDNLSVETGNRTRDKSNLARYQQCKHRQEG
NNLTACTQLRKKHRGKSFVI--------STSGLSQSEMHINLN-GKQRSYDYLSIHSTQN
TISGEYDNHEERRYSYICMVSIPGNSTMSSSHLVLAPGSPAIQKEVLLSGLEREIICVSL
KRDPKNGFGFVIIGGENVGKLDLGIFIASII-PGGPADRAGNIKPGGRLISVNNISLEGV
SFNTAVKIIQNSPDEVELII SQPKGIKANIFAGYGV-LAINSGHWYLLGSVSMKKSNQLW
ALFFTAKYQYGFADIYEEGLNEEKSLSRGNSTSGYEISCVDSGRKKIQDCHTALPK---E
KDPNIDELEKALSWSLAPKLGP-RIPVLSSDSLDVEGYKCYHSRRTLTAGSKPLYLLETH
SLFLHEADSSHLPHPAETISNEIY TVELVKEDGTFGISV--TGGINTSVPLGGIYVKSII
PRGPADKDGQIKIGDRLLEVDGISLCGLTHKQAVENLKKSGQVAKLVL ERGHHPPAQPCL
SANDGKEDQCAVVSVATSFTDGTKDYCFLTDDNIF EVKLTKNSGGLGFSVLQMEGDGCEH
LGGVIVRIKRLFPGQPAEENGEIEVGDIILAVNGTSTQGLFYQDVLHLLRGAPPEVILLL
C RPPKGVLPEIEQCVPTPAPSPVKEFVAEMPGSPEAGNSLDRSTSDGGSTSPDLEDCLDS
PVAADFSEPPEEDSSTYEEQEAESQDM-----SIQRLMPPRESSY--KDLWKFHQEAA--
-----SSEA-FHSLEEEVKQNCYSPCELGCAERSGGAITAIHTFSSSLTREETSFTL---
-M------KISIARKIMDSSQEEMEV FVTLTRSENNGYGFSVVLNKVDNCLYVDEILHEP
ALSDGRLRRGDRLIMVNGIDVTSLPCNEALTLLHNSPPDLHLVV GRAGSDPCPAVRP---
-------DDIP EITLTKGANGQLGLKLTGGAGSKLQGIYVLEIVPGSPASVEGSLQPRDQ
----ILYICGLWTEGISLDDAVRVCEAATQNVQIKA TRNGNPVVPIDQLFCFS-LPSFS-
------RFHA-I-------QDTGPQGRNAQDPQ-----RYFKQTKA----VLGRRSCESL
AAEDSGTATVGLSEEAD--------LDETKVNKFQGRRIQP-----DVQQANIIKSILRK
---------EDEEAPLMG---DQRIISQKCAGCEGCRRQSQQSESDSWNNEDDDMPHRIS
ILPRSNHAKNSLVSLMTAMTHKSNCDEQIAKEEMSKGNGDTNFQETVGNSRAFVSEDELI
HLINFKPSLTGVCPRTGVRGLIRGLQTRIENQEVLKEFMALEHVKPTEDCRTGKAQE NRD
KNRYQDILPYDKTRVPLGENKGYINASYIRMKVGEEEHFFIITQGPLPSTMADFWQMIWE
SESDVIAMMTKEVELGKVKCHRYWPEPPHDSIDLTNFHLRLDSHQILEYFIVRIIEMINK
QTEEKRIIRHLQFTTWPDHNTPKLAEQLVKFICYMRKAHRTGPIVAHCSTGIGRSGVLLC
AEILLSYIEKDLCFNIKHIVRDLREQRFGMIQTKDQYLFCYEFVLEVLQKLQA

MQPLTQNTGMSPASVTLASALQVRGEALSEEEIWSLLYLAAERLLEDIRE-------DSS
DYVVCPWSALLSAAGSLSFQNHISHIEAAPFKAPELLQEQSDNE-QPDASQVHVYSLGMT
LYWSAGFHVPQNQPLQLR-EPLSSILLTMCEDQPRRRLPLQSVLEACRVHWEEVAVYPTS
AGLHVRRLAGLVLGTISEVERRLMEE------SSLAQQDRSCLLRHRLHQASC-ENTTVW
ALERLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPGLSTS-----------------APSHHSLSVSSALPIEVPPNL-----------
------------------------------------------------------------
--------------QEGPRLS---------------------------------------
----------SST--ALSVAAEISQPAT--PSQRAFLQRKGK---FSRP---EFVLLAGE
APVTVHLPGSIV---TKKGKS-------YLALRALCVVLLSGQCLEVKCDIMSTAGAVFS
AVMSFVNLGELTYFGLAYMKDKEFFFLDDETRLCKIA PEGWSEQPQKKTSSNTFTLFLRI
KFFVSCCAQ LQNSQARHQFYLQLRKDILEEKLYCNDETLLQLAVLA-------LQAEFGN
YPEE----QI--ESKAYFRVEDYIPASLIERMTAFRLQVEVSEMHRLSPVLWGEDAELEF
LRVTQKLPEYGVLV HRVLPEKMTR ER-EMALGICAKGIIVYEVKNNSRIATLRFQWREIG
KISTCRKKFTITSGITGKKHTFVTDSAKTCKYLLGLCSAQHGFNAQ MSFLP-VA-A-VSD
HDKCVQMANT-------------------------SLAH--LAQSQPLTWIQRLSDSE--
-----NALFTPAP--GPEATAGGL--RRLSLDNFTLETSKETAA-RGIRG-SPCMGREQL
--------------ETISLIQKPTTR-DRLSGPPVPSV----------------------
---------------------------------H--REPQSNRRKSFIAEPEREIVH VTL
RRDPRRGFGFVINEGEDVGKVDPGIFISSII-PGGPAEKAKRIKPGGQILALNHISLEGF
TFDMAVRMIQNSPESIELT ISQSKGICGNTPSEEKN-SPANSGVFS--------------
---------------------------------------TDSP---SNGHLGSFSSRTQD
QEKNTEELEMAQTQSLLS------------------------------------------
--RGQDAGTSCPPPPSEINASEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILRGDRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLV LERRGPRTTQQCP
SVNGRMADGCTAVSLATALPDRPASCVSATDGPKFE VTLKKNASGLGFSFMQMERESCSH
LKNDLVRIKRLFPGQPAEENGAIAVGDIILAVNGRPTEGLVFQEVLHLLRGASQEVTLLL
CRPPPGALPEIDQGWQTPVLSADKEFTRATCTDSEQSPSLDQEDSRRDSASPDTGESLGP
GPE-SFQKATGKAQ---WDQ-DIERPWA-------TSS--MRPQDSPPHLCRLQQEMD--
------ASTLATSLERDMRQNCYSVCDIRGLERFSY--------SPSLTRLSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQGKSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLC-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
APECLHPCRVSERS-ME------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPHWSTS-----------------THSHCSLLVNRALPGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VHSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIA PEGWREQPQKT-SMNTFTLFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLYCNEEVLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEEAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-EMALGICAKGVIVYEVKNNSRIAMLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QARSKPLIWIQRLSCSE--
-----NELFAS----RLQDAAGGL--LSTSLDNFNVNGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSM----------------------
---------------------------------R--AGSKNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYSGQADPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVGGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSHTQD
QDRNTEELDMAGVQSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV LERRVPRSTQQCP
SANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGL
RPE-SSQKAVREAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ESTLATSLEKDVRQNCYSVCDIMRLG----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTQDAGMSPASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRG-------GSS
DYVVCPWSVLLSATGSLSFQDHVSHIEAAPFKAPELLPGQSDDEQQPDASQMHVYSLGMT
LYWSAGFHIPPNQPLQLC-EPLHSILLTMCEDQPGRRLPLQSILEACRIHWEEVAVHPAS
ASLHVRQLVGLVLGTISEVERRAVEE------SSSGQQDRSYLLRNRLQQASC-ESRAAR
APGCLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPRLSAS-----------------AHSCCSLSVNSVLPAEVPPDL-----------
------------------------------------------------------------
--------------QEGRQLS---------------------------------------
----------SGS--ALP---ENSRLAA--SSGKGFLQRKGK---FSRP---EFALLAGE
APVILYLPGTIV---TKKGKS-------YLALRALCVMLLNGQCLEVRCDITSTVGAVFS
AVASFANLGELTYFGLAYMKGKEFFFLDAETRVCKIAPEGWSEQPQKKSSLDTFTLFLRI
KFFVSHYGLLQHSWTRHQFYLQLRRDILEEKLYCNDEMLLQLGVLA-------LQAEFGS
YPEE----QV--ESKAYFRVEDYIPASLIERMTALRVQVEVSELHRLSPALWGEDAELEF
LRVTQQLPEYGVLVYQVLPEKTRPGG-EMALGLCAKGVIVYEVRNNSRIATSRFQWREIE
KILAYRKKFIITSSITGQKHMFVTDSAKTCKYLLGLCCAQHGFNARTSSPGVT-----TD
YDKCVQMANL-------------------------SLAH--LAQSKPLTWIQRLSCSE--
-----NALFVP----RLEGAAGGL--LHTSLDNFTVDTSKGTRA-QGLRG-RPCPGHEQL
--------------EHICLTQKPTTC-DPLSGRPAQST----------------------
---------------------------------H--TGPQNKRRRSFTAEPDREIVRVAL
SRDPRRGFGFVINEGEDVGKVDPGIFISSII-PGGPAEKAKKIKPGGQILALNHISLEGF
TFDMAVRMIQNSPDNVELII SQSKGVCGNTSSEEKN-STANSGVFS--------------
---------------------------------------TDSL---SNGHLGSFSSHTQD
QERNIEELEMARTQSLMPRLRP-QLSAPPL------------------------------
--KX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX DRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLVL ERRGPRTAQQCP
SASDRMGDECTAVSLATVLPGRPASSVSATYGPRF EVKLRKNASGLGFSFVQMESERCGH
LKNDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRPTEGLDFQEVLHLLRGASQEVTLLL
SRPLPGVL-EMDQGWQTPVLSADKEFTRATGTDSEQSPSLDQEDSQRDSASADAGEGLGL
RPE-SFQQATGEAQ---WDQ-DTERPWA-------TSL--TRPRDSYPHLFRLHQEMD--
------ASTLATSLENDMKQNCYSVCDIRRLERFSY--------SSSLTRLSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--VNPLSKGMSAASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRV-------DSS
DYVVCPWSALLSAAGSLSFQDHISHIEATPFKAPELLQGQSDDE-RPDASQMHVYSLGMT
LYWSAGFHVPPNQPLQLR-EPLHSILLTMCEDQSSRRLPLQSVLEACRIHWEEVAVDSAS
ASLHVRQLVGLVLGTISEVERRAVEE------SSSGQQDRSYLLRNRLHQASC-ETRAVR
DLGCLHPCRVSGRS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPGLGTS-----------------AQSHSSLSVNSALPVEVPPGL-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--AVQ---ENSRPAT--PSQRGFLQRKGK---FSRP---EFALLAGE
APVTLHLPGSIV---TKKGKS-------YLALRDLCVVLLSGQCLEVKCDITSTAGAIFN
AVASFANLRELTYFGLAYMKGKEFFFLDAETRLCKIA PEDWSEQPQKNSSLNTFKLFLRI
KFFVSHYAL LQHSWTRHQFYLQLRKDILEEKLYCSDEMLLQLGVFA-------LQAEFGS
YPEE----QV--ESKAYFHVEDYIPASLIERMTALRVQVEVSEMHRLSPVLWGEDAELEF
LRVTQQLPEYGVLV YHVLPEKTKP EE-EMALGICAKGVIVYEVRNNSRVATLRFPWREIE
KILAYRKKFMITSSITGKKHTFVTDSAKTCKYLLGLCCAQHGFNAQMS SPGVT-----TN
YDKYVQMANV-------------------------SLAH--LAQSKPLTWVQRLSCSE--
-----NALFVP----GLEDAAGSL--GHTSLENFSTDTSKGPGV-QGLRG-SPCLGREQL
--------------ERLCLIQKPTTC-DALSGLPVQSM----------------------
---------------------------------R--MGPQNNRRRSFTAEPDREIMHVAL
T RDPYRGFGFVINEGEDVGRASPGIFISSII-PGGPAEKTKKIKPGGQILALNLISLEGF
TFDMAVRMIQNSPDNIELI ISQPKDICGNTSSEEKN-STANSGVFS--------------
---------------------------------------TDSL---STGHRGSFSSHTRD
QERNTEELEMAQTPSLMPRLRP-PLSTPPL------------------------------
--KG--AGSSCLPSHSETNASEIYFVE LVKEDGTLGFSV--TGGINTSVLCGGIYVKSIV
PGGPAAKEGRILQGDRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLV LERRGLRTAQQCP
SANDRMEDERTAVSVATVLPGRPVSSVSATDGPKFE VKLKKNAGGLGFSFVQMESESGSH
LKNDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRPTEGLDFQEVLHLLRGASQEVTLLL
CRPPPGALPEMDQGWQTPVLSADKEFTRATCTDSEQNPSLDQEDSQRDSASPDPGEGLGL
RPE-SFQQAPREAR---WDQ-GIERCWA-------TSL--MQ------------------
--------------------NSYSVCDIRRLE-------------SDGEEGDMYYPP--E
AP----------------SPTLEDEVYLTIN-----------------------------
-----------------STMEDQLPCGECLEADSGTIPLPQFCSWG--TFSE-SLPPEES
CDSEGEWEDLEEAENQM--MAPSGG----YHS--V---W----VE---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--MHVFIIGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLC-EPLRSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
APECLHPCRGGCTIQLG------PQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-PRSAPSWPVS---------------------CWLWGMRAGGGCRG--------------
------------------------------------------------------------
------------------------------------------------------------
-----------AS--WGKP-RPKAWNLL--S-SLPYVTVFLQ---FSR---PEFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIA PEGWREQPLKT-SMNTFTLFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-EMALGICAKGVIVYEVKNNSRIAMLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAAGGL--LSTSMDNFNMDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSM----------------------
---------------------------------H--AGSKNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYSGQADPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVGGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSHTQD
QDRNTEELDMAGVQSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLKGPGQVARLV LERRVPRSTQQCP
SANDSMGDERTAVSLVTALPGRPLSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIAAGDIIVAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGL
RPE-SSQKAIREAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ESTLATSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EGDMYHPCG
AP----------------SPTSEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTIPLPQFCSWG--TVPE-PLPPEES
PESGSEWEDLEEPVALE--YGALRW----VS---L---W----LGGL---ELSSDQSRAQ
CYQATSSGGGGWSVGIAQFP----------------------LHLLWG-HVSL-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLC-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLRGTSS-ESPAAQ
APECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPHWSTL-----------------THSHCSLLVNRALPGADPQDQ-----------
------------------------------------------------------------
--------------QAGRRLS---------------------------------------
----------SGS--VHSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIA PEGWREQPQKT-SMNTFTLFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKF
LRVTQQLPEYGVLV HQVFSEKRRP EE-EMALGICAKGVIVYEVKNNSRIAMLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QARSKPLIWIQRLSCSE--
-----NELFVS----RLQGAAGGL--LSTSMDNFNVDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSM----------------------
---------------------------------H--AGSKNNRRKSFIAEPGREIVR VTL
KRDPHRGFGFVINEGEYSGQADPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVGGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSHTQD
QDRNTEELDMAGVQSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLV LERRVPRSTQQCP
SANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGL
RPE-SSQKAIREAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ESTLATSLEKDVRQNCYSVCDIMRLGRYSF--------SSPLTRLSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDTGMSPGSVTLASTLQVRGEALSEEEVWSLLLLAAEQIVEDLRN-------DSS
DYVVCPWSALLSAAGSLSFQGHVSHIEAAPFKAPELLQGQSDDG-QLDVSQMHVYSLGMT
LYWAAGFHVPPNQPLPLR-EPLLSLLLSMCEDQPRGRRPLHSVLEACRVREKAVAVYPAP
ASLHVRRLVGLVLGTISEVERRVVED------GGSAQQSRSYLLRKRLHHAGG-ASPAAR
ARERAQPCGVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPHASTS-----------------ACSHCSHFVNRALPGAVPQDH-----------
------------------------------------------------------------
--------------REVQQLS---------------------------------------
----------SGS--ALSG-AESSRPAT--PSQMGFLQRKGK---FSRP---EFVLLAGE
APVTLHLPGSVV---TKKGKS-------YLALRDLRVVLLSGQCLEVKCDMASTVGAVFN
AVMSFANLGEIAYFGLAYVKGKEFFFLDSETRLCEIA PEGWREQPQKA-SVNTFTLFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLCGDDETLLQLGVLA-------LQAECGN
YPKE----QV--ESQAYFRVEDYIPASLIERMTAPQVQAEVSERHRLGSALSGEDAELQF
LRVTQQLPEYGVLV HRVFPEKKRP EG-ELALGICAKGVIVYEVRNSSRIATLRFQWRETR
KISTYQKKFTITSSVTGKKHTFVTDSVKTCKYLLGLCSAQHGFNAQM GSGRPPQVLTD--
HDKFVQMASS-------------------------SPAH--QAQCKPLTWMQRLSCSE--
-----NQLFAP----GLQGAAGGL--LSTSLDNFHVEAGKELAA-EGMAA-SPCTGWEQL
--------------ETACVIQKPTTC-DPLSGPPVQSL----------------------
---------------------------------C--TGSHNDRSKSFAAEPGREILR VTL
RRDPQRGFGFVINEGENAGQADPGIFISAII-PGGPAEKAKNIKPGGQILALNHISLEGF
TFSMAVRMIQNSPDDIELI ISQPKGVCGNTPDEQKN-STANSGVFS--------------
---------------------------------------TDIL---SNGHQGSLSSHTQD
QHRNTEEPGVAQVQSLMSRLRSR-LSPLPL------------------------------
--KD--AGSSRPSSPSETKAGEIYFVE LVKEDGTLGFSV--TGGINTSVLYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV LERRGPRTSQQCP
SANDRMGDEHAAVSLVTALPGSPSSCVSVTDGPKFE VKLRKNASGLGFSFVQVEKGSCGH
LRSDLARIKRLFPGQPAEENGAIAAGDIILAVNGRPTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPDMEQGWQTPVLSADKAFTRAACTDSERSPSLDQEDSWRDSASPDTGEGLGL
RPE-SSQKAIREVQ---WGQ-DRARPGA-------RSL--MRPPESHPHLCNLHQERD--
------ASTLATSLEKDIRQNCYSVCDISRLGRFSL--------SSSLIRLSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

-NPVSTASGMSNSCVTLAEVLWAKGSPLEEEEIWALLYLSTVQLLEDLHK-------DPA
ICVICPWSVLLSAEGNLFFQSNASQTEAAPFSPPELLHRPSKNQ-HFGLTKMLVYSLGMT
LYWSADYQVPPNQATQLS-DQLHALLLTLCEDLPHRRLSPESILEACEAHQKESASLP--
AKFYIKKMVQFAVGSVSEVKQVVTED------SAASQLSRSHVIRKRLHENISDTS-TLA
SQMNFHQARTQERRLP------THGSC---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------D--TTLSGSRTQSSYKLFI---NSVAMPPYLDPGEPTEER
H------QTERSHQSAFA----PY------STLKSIRSSIQQYKLFSGP---EFIILSSE
PPVTLQLPGSIV---TKKGKS-------YLSQRDLNVILLNGQCLEVQCDIKTKARDVFN
TVVAYANLVEHFYFGLAYLKGKEFFFLDEETKLYKVAPDGWNDQPKKKMSIINFTLFLRI
KFF VNHF NVIQHGLTRHQFYLQLRKDILEERLYCSDETALKLGALA-------LQAELGN
YASEQ----R--TSVNYFRVEDYVPASRIEKMTLAYVQRELAKLHRMNRSLFEDEAELEF
LKVTQQLPEYGVLF YRVSQEKKGT EG-DIILGICAKGIIVYENKNQTRIASLRFQWRETE
RISAHRKKFMIESSFSGKKHTFITDTAKTCKYLLDLCSAQHKFNAQMNSRQLRQTSSEDS
K----------FVE-------------------IDKSNPAYAAQHEHLALIQRLSRSE--
-----NVLYGA----NLENLSAGM--MSKSCDNLSVETS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------RHDFTRHQFYLQLRKDILEERVYCSDEMLWQLGSLA-------LQAEFGN
YTAE-----V--QDRNYFWIEDYLPASMIERVTASYAQQQISEMHRLRCPLFVDEAELEF
LKMTQQLPEYGVLF YRVFQEKRLL-G-EMILGICAKGIIVYEIRNSSRIASLRFQWQEAE
KIYTHRKKFTVESRFSGKKHTFVTDTAKTCKYLLDLCSAQHKFNAQMGSGHFYR------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--MHVFIVGMNLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQGQSEDE-QPDASQVSLLRML--
---ELCLHFSPCSSMSLCSIPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
APECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPHWSTS-----------------THSHCSLLVNRALPGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VHSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIA PEGWREQPQKT-SMNTFTLFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-EMALGICAKGVIVYEVKNNSRIAMLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QARSKPLIWIQRLSCSE--
-----NELFAS----RLQDAAGGL--LSTSMDNFNVDGSKEAGA-EGIGL-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSM----------------------
---------------------------------H--AGSKNNRRKSFTAEPGREIVH VTL
KRDPHRGFGFVINEGEYSGQADPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVGGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFRYQGSLLSHTQD
QDRNTEELDMAGVQSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLKGPGQVARLV LERRVPRSTQQCP
SANDSMGDERTAVSLVTALPGRPLSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGL
RPE-SSQKAIREAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ESTLATSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EGDMYHPCG
AP----------------SPTSEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTIPLPQFCSWG--TVPE-SLPPEES
PESGSEWEDLEEPVALE--YGALRW----VS---L---W----LGGL---GLSSDQSRAQ
CYQATSSGGGGWSVGIAQFP----------------------LHLLWG-SCVIVMAIFTE
HLPWPLHHDNDLQHGDCHHPHF--------------THDTFG-----AFPRLSNK-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--PKSQEASMSPASVTLASAVQVRGEALSEGELWSLLFLAVERLLEDLHD-------ESS
DYVVCPWSALLSVTGNLSFQDHVSHVEAAPFKAPELLQGQSNDE-LPDVSQMHVYSLGMT
LYWSAGFHVPPNQPLQLC-EPLHSILLTMCEDQPYRRLSLQSVLEACQVHQQEVAIYPAP
AALHIRRLVGLVLGTITEVERRVVEE------NTPLQQGRSYLLRKRLQQAST-------
-PRSLHPSRVSERS-TE------IQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPCSSAS-----------------AHSGCSLFVNSALPAEVPQDL-----------
------------------------------------------------------------
--------------QEGHRFS---------------------------------------
----------SGS--AFSVASENSRPAA--PSQRGFLQRKEK---FSRP---EFVRLAGE
APATLHLPGSIA---AKKGKC-------YLALRDLRVVLLSGQCLEVKCDTESTVGAIFN
AITSFEDLGEVTYFGLAYLKGKEFFFLDNETRLCKVAPEGWSTRPQRKTPASVFTLFLRI
KFFVSCVGLLQQSQTRHQFYLQLRRDILEEKLYCNDETLLQLGSLE-------LLIELQV
WPKE----QVK-EGKAYFQVEDYIPASLIRRMTASRVQLKISEMHCLSPALWGEDAELEF
LRVTQQLPEYGVLVHQVFPEKSQPET-EMALGICAKGVIVYEVKNNVRIATLRFGWRETG
KISACRKKFTITSSITGKKFRVVTDSAKTCRYLLGLCSAQHGFDAQMSSRPCPRVLTDSD
HETPVQRASL-------------------------NPARQ--A--------QVRPCSE--
-----DALFEP----RLDEAPRSL--QSTSLDGLNVENSKEAGK-EGTRG-SPSTGPEQL
--------------ESACMTLKPRSS-DPVCALPVQNG----------------------
-----------------------------------VPGSQNNRIKTFATKPDCEIVCVTL
RRDPRHGFGFVINGGQGVGKTDPGIFISSIL-PGGPAEKTNKIKTGGQILALNHISLQGF
TFSMAARMIQNA-DNIELII SQSEGVCEYAPREEKN-GTANPEVFT--------------
---------------------------------------ADSL---SHGHQESFPSHAQD
QNKKIEKQEMAQAPSLVARLRP-QLSPLPL------------------------------
--ES--IDSSSPSSPSETKASEIY FVELVKEDGTLGFSV--TGGINTSVLLGGIYVKSII
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHEQAVQCLKGSGQVARLVL ERRGPNTVQQCP
SANTSMGEGRAAVSLVTTLPGRPMSCVSVTDGRKF EVKLKKNSSGLGFSFVQMERESCGH
LKNDLVRIRRLFPGQPAEKNGAIAAGDIILAVNGKPTEGLVFQEVLHLLRGAPQEVTLLL
CRPPPGALPEIEDGWQTPARSAVEEFTKSTGTDLELSPSLDQEGSPRDGASPDTGEGLDL
RPE-SFQKVLWDQ-----DT-HLERPWA-------SCSTHPCPQDAHILLYRLKQEMD--
------ASPSATSLEKEVRQNCYSVCDIRRFER---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKNAGMGPDSVTLASVLQVRGEALSEEEIWSLLSLAAERLLEDLRN-------DSS
DYVVCPWSALLSAAGSLSFQDHVSHIEAAPFKAPELLQGQSDAE-KPDVAQXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXVERTVVEE------SSSVQQSRSYLLRKRLHRAGS-ASPVAR
ALDCLHPCTXXXXXXXX------XX-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-XX-XXXXXXX-----------------XXXXXXXXXXXSLPGTAPHDP-----------
------------------------------------------------------------
--------------REGRRLS---------------------------------------
----------FGS--AISEAAESSQPATPTPSQRSFLQRKEK---FSRP---EIVLLAGE
APVTLHLPGSVV---TKKGKS-------YLALRDLCVVLLSGQCLEVKCDTESTAGAVFN
TVMSFANLGELSYFGLAYMKGTEFFFLDNETRLCKIAPEGWKEQSQKT-SVGTFTLFLRI
KFFVSRCELLHHSLTRHQFYLQLRKDILEERLYCNDETLLQLAVLA-------LQAEFGN
CPKE----PA--ERRSFLD--SKITTSLIEK--------------------------TPL
WVVSQQLPEYGVLVHRIFPEKK-LDG-EMALGICAKGIIVYEVKNNLRIATLRFQWRETG
KISTYRKKFTITSSITGKKHTFVTDSSKTCKYLLGLCSAQHRFNAQTCSGQSPLVLPD--
HDTLVQMANV-------------------------SPAH--QARSKPLLWIQRLSCSE--
-----NELFAS----RLQAAAGGP--LSVSLDNFSVDASKEAGT-EGTRG-SSCTGHRQL
--------------ETLGLIQKPAIC-ERHSGPPGESVC---------------------
------------------------------------PGSQNNRRKSFTVEPGREIVCTTL
SRDPQRGFGFVINEGEDPG-ADPGIFSSI----PGPAEIAKKIKSGEQILALNHISLEGF
TFDMAVKMIQNSPERIQLTV SQPEGVCGNTPREEKN-SMAHSGVCP--------------
---------------------------------------ADL----SNGHRGSSSSHTQD
QDRSADELEAAPAPSLLPRPES-QLCPLPL------------------------------
--RV---AGLCPPSPSEINAGEIY FVELVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGG-AAKEGQIQQGDRLLQVDGVSLRGLTHRQAVQCLKGPGQAARLVL QRRGPGAAQQCP
-ANDRMGDEHAAVPLVTALPGRHSSCVSVTDGLTF EVTLRKNAGGLGFSFVQMERASCSH
LRNDLVRIKRLFPGQPAEENGAIAAGDVILAVNGRPTEGLTFQEVLHLLRGAPQEVTLLL
WRPPPGVLPDLEQDWQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XXXXXXXXXX---XXX-XXXXXXX-------XXX--XXXXXXXXXXXXXXXXXX--
------XXXXXXXXXXXXXXXXXXXXXXXXXXXFPF--------SSSLTRLPTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--MHVFFVGMSLSSVTLASALQVRGEALSEEEIWSLLSLAAEQLLEDLHN-------DSS
DYVICPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQRQNEDE-QSDASQMHVYSLGMT
LYWSAGFHVPPNQPLQLH-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRKLVGLVLGTISEVEKKVVEE------SSCVQQNRSYLLRKRLHGTSG-ESPAAQ
APECPHPCRVPAWA-GG------TH-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------SIVSCPVGATHPHWADPQHQ-----------
------------------------------------------------------------
--------------EEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFVLLAGE
APVTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQRLEVKCDVESTVGAVFT
AVMSFANLEELTYFGLAYMKGKEFFFLDNETRLCKIA PEGWREQPQKT-STNTFILFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLYCSEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEVSEIHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKKRP EE-EMALGICAKGVTVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQM GSGPPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFTS----RLRDAAGGL--LSTSLDNFNVDTSKEAGA-DGIGR-SPCTGREQL
--------------KSACVIQKPTAW-DSLSGPLVQGM----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVH VTL
KRDPHRGFGFVINEGEYSGQADPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNAQNEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSL-SHTEN
QDRNIEELDMVGAQSLVPRLRH-QLSFLPL------------------------------
--KG--SGSSCPLSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV LERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGLKFE VKLKKNANGLGFSFVHLEKECFSH
LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTLELSADKEFTRATCTDLCTSPSLDQEDSWRDSASPDAVGSLGL
RPE-SSQKAIREAQ---WGQ-DRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLATSLEKDVRQNCYSVCDILRLGSPES----------EDR--EGAMCHPHG
AH----------------SPTLEDEKYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTIPLPQFCSWG--TVPE-SLPPEES
QESGSEWEDLEETVDLE--DAALRV----HLS--PRVSL----FWGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVICPWSALLSATGSLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDVSQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
ASLHIRKLAGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPEAQ
ASECLHPRRVSEKG-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPHWSTS-----------------THSHCSLLVNRALSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VHSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-STNTFTLFLRI
KFFVSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTVLRVQVEVSEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQTANL-------------------------SPAH--QVQSKPLIWIQRLSCSE--
-----NELFAS----KLQDAVGGM--LSTSLDNFNVDGSKEAGA-EGIGR-SPCTGQEQL
--------------KSACVIQKPMTW-DSLSGPPVQSV----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSYTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANDSMGEEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPEAGEGLGL
RPE-SSQKAIRAVQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EDDMYHPCG
AP----------------SPTSEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTILLPQFCSWG--TVPE-SLPPEES
PESGSEWEDLEEPVDLE--YGALR-------S--L---S----FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

-MHPTQDTGMSPAPVTLASALQVRGGALSEEEIWSLLSLAAERLLEDLRDXXXXXXXXXX
XXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXWHVYSLGMN
LYWSAAFGVP-KQPLQLG-ETLHSLLLTMCEDQPRRRLPLQSVLEACWAHRQEVAGSPAS
ASLHVSQLVTLVLDTISQVEKRVVEE------KSFVQQDRSYLLRARLHQASCERP-PAY
PKCR-HPCGISERN-----------TETQ-------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLKPAPSFST-----------------HSHCGVFVNXXXXXXX---------------
----------------------X-----------------XXXX-------------X--
-XXX-------------XXXX---------------------------------------
----X--XX-X-----------XX--XXXXXXXXXXXXXXXXXXXFSRP---EFLLLPRE
APVTLHLPGSIV---TKKGKS-------YLALRDICVVLLSGQCLEVKCDGTSTVGAIFN
AVTAFANIVELTYFGLAYMKDKEFFFLDNETRLCKIAPEDWNEQPPKKT-WNTFTLFLRI
KFFVHDCGLIQQSQTRHQFYLQLRRDILEDKLHCEEEMLLRLAVLA-------LQAEFGS
YPTEXXXXXX--XXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXX
XXVTQQLPEYGVLIHRVLPDKARPEGVKMALGICAEGVIVYEEKNDSRIATIRFPWREIG
KISTYRKKFTITSSITGIKHIFVTDSAKTCKYLLGLCSAQHRFNAQMSSGATXXXXXXXX
XXXX-XXXXXXXXXXXXXX--------------XX-XXXXX-----XXXXXX---XXX--
-----XXXXXX-----------XX-------XXXXXXXXXXXXXXXXXXXXXTCSGQEQP
--------------QSICLIQKPTPI-NPDSGPSVQSTCTG-------------------
--------------------------------------SQSERRKSFSAVSDADIMHVTL
SRDPCHGFGFVINDGDDAG-VGPGLFISCII-PGGPADKTKKLKPGGQILALNHISLEGF
TFNMAVKMIQNAPDKIELLISQPKDVFQKTPSEEKN-STANSGVFSTD------------
-----------------------------------------SLSN---GYQGRFSPHKQD
QVRSNREQEGTGLQSFMPMLRP-QLSFLQLKXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX-------XXXXXX-------------------------------------------
--------X-XX-------XXXXXXXXXXXXXXXXXXXXXXFSYSSPLTRLPRDIL----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MRSLMQKTGVSPASVTLASALQVRGEALSEEEIWSILLLAGERLLEDLRN-------DSS
DYVVCPWSALLSAAGSLSFQDHVSHLEAAPFKAPELIQGQSEEE-HLDAAQMHVYSLGMT
LYWAAGFRIPLSQPLRLH-QPLHTLLLAMCEDQPRRRRPLHAVLEACRAHQEEAVVSPVL
ARLHVRRLVGLVLGTLSEVEKRVVQE------DICTQQSRSYLLRRRLQPQSG-QSSEAL
APDRPQPHK--E-QCIE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSGEPRWSSS-----------------AHSHCNLFENSPLAGAAPLGW-----------
------------------------------------------------------------
--------------QDGPRSS---------------------------------------
----------SGS--MLPAEAESPRSAT--P-QQGFLQRKGK---FSRP---EFLLLAAE
APVTLHLPGSVV---TKKGKS-------YLALRDVCVVLLSGQCLEVKCDIESTVGAVFD
VVTSFINLGDVTYFSLAYVKGKEFFFLDNETRLCKIA PEGWREQPLKT-STDTFTLFLRI
KFFVSHCGL LQHSLTRHQFYLQLRKDILEERLHCDDETLLQLGVLA-------LQAEFGS
YPKE----QE--ESKPYFRVEDYIPATLIQRMTALRAQAEVSEMHQLSSALCGEDAELEF
LRITQQLLEYGVL IHRVFPEKKRL EG-EMALGVCAKGVIVYEVKNHSRIATLWFPWREIG
KISTYRKKFTITSSLTGKKHTFVTDSSRTCTYLLGLCSAQHGFHAQ AGSGQPPRLLTG--
QQKVVQTASL-------------------------SPAH--QAPWKPLSWNQRLSYSE--
-----NELFAP----KVQDGVGDL--LSVSLENFSSNGTKEIGV-EAVRG-SPCTGQEHQ
--------------DSACLIQKPTTC-DLLWGPLVQSMC---------------------
------------------------------------PGSQKNRRESFIPELGRELVHV AL
RRDPHRGFGFVINEGEDVGQASPGIFISSII-PGGPAAKTKKIKPGGQILALNHISLEGF
TFTMAVRMIQNSPDHIELT ISQAEGVCGNAPREGKD-SMAISGVFS--------------
---------------------------------------TDIL---SAGHPGRLSPHTYN
QHRDPEEQETAQAQSPTPQQRP-PCSPLPV------------------------------
--KG--VGTSSPPSPLETNSGEIYFVE LVKEDGTLGFSV--TGGVNTSVLHGGIYVKSII
PGGPAAKEGQIQQGDRLLQVDGVSLCGLTHKQAVQYLKGPGQVAKLV LERRSLGMAQQHP
SANDRMGDEHAAVSLVTALPGRLASCVSVTDGPKFE VRLRKNTNGLGFSFVQVERGSCSL
LQSDLIRIKRLFPGQPAEEHGAIAAGDIILAVNGRPTEGLVFQEVLNLLRGPPQEVTLLL
CRPPPGVLPEMEPVWQTPM---GKEFTRTTCTDSEQSPSLDQEDSWRDSTSLDAGEGLAL
G----------GAQ---GSQ-DRDRPWA-------KSLA--LP-LQSHHLCQRHKDSE--
------VSPLATPLEQDMRQNCYSVCDIRRLSRDHV---------------EGDTCYPPE
TL----------------FLTWEDEEYLSIH-----------------------------
-----------------CTSEGQLPCGDCLEVDSGTIPLPQFCSGH--ACPE-SWPLERS
HGSDSEWEDLEDPEDTM--SNTLR------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDTGMSLASVTLASVLQVRGEALSEEELWSLLSLAAERLLEDLHN-------DSS
DYVVCPWSALLSATGSLSFQDHVSHIEAAPFKAPELLQGQGEDE-LLDVSQMHVYSLGMT
LYWTAGFHVPPNQPLQLH-EPLHSILLTMCEDQPSRRRPLQSILEACRVHQEEVAVYPAP
AQLHIRRLVGLVLGTISEMERRVVEE------STCMQQSRSYLLRKRLQGTSS-ESPVAP
ALECLNLLRVSDRS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPRWSTS-----------------AHSRCSLFVNSTLAGTFPHDQ-----------
------------------------------------------------------------
--------------QEGQRLC---------------------------------------
----------PGS--VLLAEAGSSQLPA--PSQRNFLQRKKK---FSRP---EFLLLAGE
APVTLHLPGSVV---TKKGKS-------YLTLRDLCVVLLSGQCLEVKCDIESTVGAVFN
AVMSFINLGEITYFGLAYLKGKEFFFLNNETRLCKIA PEGWREQLMKT-STDTFTLFLRI
KFFVSHCG LLQDSLTRHQFYLQLRKDILEERLHCNDETLLQLGVLA-------LQAEFGN
YPKE----QT--ESKAYFRVEDYIPASLIERMTALQVQVEVSEMHRLCSAPWGEDAELEF
LRIIQQLPEYGVLV HQIFPEKKRP EE-ELALGICAKGVIVYEVKNNSRIATLRFWWRETG
KISTYRKKFTITSSVTGKKHTFVTDSAKTCKYLLGLCSAQHGFNAQM GSGQILHISAD--
RDKFVQMANS-------------------------SPAQ--QAQSKPLTWIQRLSCSE--
-----NQLFLP----RLQDTIGGL--LSASLENFNLETNKETGP-EGIRD-SPCPGQEQL
--------------NSTCLIQKPMTR-GPLSGLPFQTV----------------------
---------------------------------N--TGFQNNRRKSGSAEPGREIVH VTL
KRDRHRGFGFVINEGEDRGQSNPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELV ISQSKGVCGNNPCEG---------VFS--------------
---------------------------------------TNILS--NQGNQGSLSSRTQD
QDRTIGELKVAQLQSSMPQLS-----S--L------------------------------
--PL--KGSSCPPSPSETNTDRIYFVE LVKEDGTLGFSV--TGGINTSVLYGGIYVKSII
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQYLKGPGQVVRLV LERRGPRTAQQCP
SANDRMGDEHAAVSLVTALPGRPVSCVSVTDGLKFE VKLKKNINGLGFSFVQMERENCSH
LKNDLVRIKRLFPGQPAEEHGAIAVGDIILAVNGRPTEGLLFQEVLHLLRGAPQEVTLLL
CRPPPGVLPEMEQGWQISALSADKELTRATCTDSEHSPSLDQEDRWRDSASLDAGEDLNL
RPE-SFYKATSEAQ---GGQ-DREKLWA-------GSL--TRPLESHPHLCKLHQEME--
------PPILATSLENDLRQNCYSVCDIRRLGRFSF--------SSSLTRLATDIL----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTQDPGMSPASVTLASVLQVRGEALSEEEIWSLLSLAAERLLEDLRD-------DSS
DYVVCPWSALLSAAGSLSFQDHISHIEAAPFKAPELLQGQSDAE-QPDASQMHVYSLGMT
LYWSAGFHVPPNQPLQLC-EPLHSILLTMCEDQPCRRLSLPSILEACRVHWEEVTVYPAS
ANLHIRQLVGMVLGTTSQVERRAVEE------SSSGQRDRSYLLRNRLHQASRESP-AAQ
VLGCLHPCRVSE-----------RNTE---------------------------------
----TQSSPE------------------PRL-----------------------------
---------SAAAYS----------------H----------------------------
--------------------------------CSLSVNXXXXXXXXXXXXXXXXXXXXXX
XXXXXX---XX---------XXX-------------XX--XXXX------X------XX-
-XXXXXXX--X------XXXX--X----------X---------X---XX----------
-X--XXXXXXXXXXXX-X--XXX-----XXXX-------XXX---XXXX---X-------
----XXXXXXXX---X----------------------------------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXKEFFFLDAETRLCKIAPEGWSEQPQKRSTPKTFTLFLRI
KFFVSHCG----------LFPQLRKDILEERLYCNDEMLLQLGVLA-------LQAEFGS
YPEE----QV--ENKAYFRVEDYIPASLIERMTALQVQAEVSEMHRLSPVLWGEDAELEF
LRVTQQLPEYGVLVYQVLPEKTRPEG-EMALGICAKGVIVYEVRNNSRIATLRFQWREIE
KILAYRKKFIITSSITGKKHTFVTDSAKTCKYLLGLCCAQHGFNAQMSSPGVTPXXXXXX
XXXX-XXXXXXXXXXXXXXXX------------XXXXXXXX-----XXXXX----XXX--
-----XXXXXX-----------XX-------XXXXXXXXXXXXXXXXXXXXXPCLGREQL
ENM--------------CLIQKPTTC-DPLSGLPVRSMCTXXXXXXX-------------
--------------------------------------------XXXXXXXXXXXXXXXX
XXXXXXXXXFVIHEGEDVGKVVPGIFISSII-PGGPAEKAKKIKPGGQILALNHISLEGF
TFDMAVRMIQNSPDNVELII SQSRGVCGNTSSEEKK-ST---------------------
----------------------------AN----SRVCSTDSLS---DGHRGGLPSHTQD
QERVSEELGMARTQRLMPGMRP-RLSTLPL------------------------------
-----KDAGSRPSSPSETNASEIY FVELVKEDGTLGFSV--TGGINTSVPCGGIYVKSIV
PGGPAAKEGRILQGDRLLQVDGVSLCGLTHKQAVQCLKGSGQXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEVLHLLRGASQEVTLLL
CRPPPGTLPEMDQGWQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX--XXXXXXXXXXXXXXXX-----XXXXXXX--XXXX--XXXXXXXXXXX--
--------X-X--------XXXXXXXXXXXXXXXXXXXXXXFSFSSSLTRLSTDIS----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDTGMSPASVTLASTLQVRGEALSEEEIWSLLLLAAEQIMEDLHN-------DSC
DYVVCPWSALLSAAGSLSFQGHVSHIEAAPFKAPELLRGQHDDE-QWDVSQMHVYSLGMT
LYWAAGFHVPPNQPLQLR-EPLLSLLLAMCEDLPCRRRPLHSVLEACRAREKEVAVYPAP
AGLHVRRLVGLVLGTISEVERRVVEE------SSSMQQNRSCLLRKRLQQASS-ASPAAW
APAWARPCRVSERS-TE------PE-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPHSSAS-----------------AHSRCSRFATCTLPEAAPQDQ-----------
------------------------------------------------------------
--------------REVQQLS---------------------------------------
----------SRP--TPSG-AESSLPAT--PSQTGFLQGRGK---FSRP---EFVLLAGE
APVTLHLPGSLV---TKKGKS-------YLALRDLCVVLLSGQCLEVKCDMASTVGAVFN
AVMSFANLGEVTYFGLAYMKGKEFFFLDNETRLCEIA PEGLREQSQKP-SMNTFTLFLRI
QFFVSHCGL LQHSLTRHQLYLQLRKDILEERLCGDDETLLRLGVLA-------LQAECGH
YPKE-----V--ESQAYFRVEDYIPASLIERMTALQVQAEVSERHRLSSALWGEDAELQF
LRVTQQLPEYGVLV HRVFPEKKRP EG-ELALGICAKGVIVYEVKNSSRIATLRFQWRETR
KISTYQKKFTITSSVTGKKHTFVADSVKTCKYLLGLCSAQHRFNA QLGSGRPPQVLTD--
HDKFVQMAHL-------------------------SPAH--QAQCKTLTWMQRLSSSE--
-----NELFAP----GLQGAAGGL--LSTSLDNFHVEASKELAE-EGPGA-SPCTGREQL
--------------ETACLIQKPTTC-DSLSGPPAQSL----------------------
---------------------------------C--TGPQNNRSKSFAAEPGREIVC VTL
KRDPQRGFGFVI-KGENAGQADPGIFISAII-PGGPAEKAKHIKPGGQILALNHISLEGF
TFSMAVKMIQNSPDDIELI ISQPKGVCGNAPNEPKI-STATSGVFS--------------
---------------------------------------TDTL---SIEHQGSLSSHTQD
QDGNIEEPGVARVRSPTSRLRPPQLSLPPL------------------------------
--QD--AGSSHPSSPSESKAGEIYFVE LVKEDGTLGFSV--TGGINTSMLCGGIYVKSIV
PGGPAAKDGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV LERRGPRTAQQCP
SANDRIGDEHVAVSLVTALPGRTSSCVSVTDGPKFE VKLRKNANGLGFSFVQTEKESCGL
LRSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRPTEGLVFQEVLHLLRGAPQEVTLLL
CRPPPGALPDMEQGWQTPVLSADKGFTRAVCADSEWSPSLDREDSWRDSTSPDAGAGLGL
RPE-SSQKAIREAQ---WGQ-DGERPWA-------GSL--MRPPEPAPHSRSLHQGRG--
------APASATSLEKDVRQSCYSVCDLRRLGSPEQ--------DRDHEDIDKCHPP--G
TP------------------------SLTAS-----------------------------
-----------------PTPKGQLPCGECLEADAWAIPSSQFCSWG--TLSE-PSPPGES
YESESKWEDLEGPVGLE--DSARR------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------REIICVSL
KRDPKNGFGFVIIGGENVGKLDLGIFIASII-PGGPADRAGNIKPGGRLISVNNISLEGV
SFNTAVKIIQNSPDEVELI ISQPK------------------------------------
------------------GLNEEKYLSRGNSTSGSETSCVDSGRKKIQDCHTALPK---E
QDTYTDELEKTLSWNLASKLGP-RIPFLFL----RQ------------------------
-----AADSSHLPSPSETNSREVYVV ELVKEDGTFGISVTASGGINTSVRHGGIYVKSII
PRGPADKDGQIKIGDRLLEVDGISLCGITHKQAVEHLKKSGQIAKLV LERGNYQLAEPCL
TANDRKEDHRAVVSVATSLTDGTKDCCFLTDDNIFE VKLTKNSGGLGFSVLQMEGDACEH
LGGAIVRIKRLFPGQPAEESGEIEVGDVILSVNGKPLKGLLYQDVLHLLRGAPREVTLLL
CRPPKGVLPEIEQ-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDTGMSLSSVTLASALQVRGEALSEEEIWSLLFLATEQLLEDLRN-------DSS
DYVVCPWSALLSATGNLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
ASLHIRKLAGLVLGTISEVERRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
ASECLHPCRVSERS-ME------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPDPHWSTS-----------------THSHCSLLVNRALSRADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--P-QKGFLQRRSK---FSRP---EFILLAGE
APTTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-STNTFTLFLRI
KFFVSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEISEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFDSD
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAVGGM--LSTSLDNFKVDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTR-DSLSGPPVQSV----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSRTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--TGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSTDKEFTRATCTDSCTSPILDQEDSWRDSASPEAGEGLGL
RPE-SSQKAIRAAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIMRLGRYSF--------SSSLTRPSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDTGMNLASVTLASALQVRGEALSEEEIWSLLSLAAEQLLEDLHN-------DSS
DYVICPWSALLSAAGSLSFQGQVSHIEAAPFKAPELLQGQSDEE-QFDVSQIHVYSLGMT
LYWAAGFRVPPNQPLQLR-EPLHSILLTMCEDQPHRRRPLQSVLENCRVHEKEVAVYPAP
AGLHIRRLVGLVLGTISEVERRVVEE------SSSVQQNRSYLLRKRLHQATS-ESPVAQ
ALESLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPHSSTS-----------------AHSHCSQFVNRTLPGAVPQDH-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--ALSR-AESSRPAT--PSQRGFLQRKGK---FSRP---EFVLLAGE
APVILHLPGSVV---TRKGKS-------YLALRDLCVVLLNGQCLEVKCDMESTAGAVFN
AVMSFANLGELTYFGLAYMKDKEFFFLDNETRLCTIAPEGWREQSPKT-SMNTFTLFLRI
KFF VSHYGL LQHSLTRHQFYLQLRKDILEERLHCSEETLLRLGGLA-------LQAEFGN
YPKE----QV--ESQVYFRVEDYIPASLIERMTPLRVQVEVSEMHRLSSVLWGEDAELEF
LRVSQQLPEYGVLV HRVFSEKKRP EG-ELALGICAKGVIVYEVKNSSRIATLRFQWRETR
KISTHQKKFTITSSVTGKKHTFVTNSAKTCKYLLGLCSAQHGFNAQ MGSGPSPQVLTD--
HDKFVQLVNL-------------------------SPAH--SAQSKPLTWIRRLSCSE--
-----NELFAP----RVQDAAGGL--LSTSLDNFHIEASKEVGA-EGVRA-SPCTGREQL
--------------GNTCVIQKPS---DSLSELPVQSL----------------------
---------------------------------P--PGSQNNRNKSFTAEPGREIVC VTL
KRDPHRGFGFVINEGDNAGQADPGIFISSII-PGGPAEEAKRIKPGGQILALNHISLEGF
TFNMAIKMIQNSPDNIELI ISQSKGVCENIPNEEKS-TTANSGVIS--------------
---------------------------------------TDIL---NNGHQGSLSLHAQD
QDRTTEGPGVAQVQSFVSSCLF-YC-VCLG------------------------------
--QD--AGSSCPPRPSETKPGEIYFVE LVKEDGTLGFSV--TGGINTSVLHGGIYVKSIV
PGGPAAKEGQILLGDRLLQVDGVSLYGLTHKQAVQCLKGPGQVARLV LERRGPRTAQQCP
S-NDRMGDEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMERESCSH
LKNDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRPTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGVLPDMEQGWQTPVLSADKAFTRATCTDSERSPSLDQEDSWRDSASPDTGEGLGL
RPE-SSQKAFREVQ---WDQ-DRERPWA-------GSL--MHSPSSHPHLCNLHQERD--
------ASTLATSLEKDIRQNCYSVCDIRRLGRFSL--------SSSLTRLSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

-------AGMSPTSVTLASALQVRGEALSEEEIWALLSLAAERLLEDLRD-------DSS
DYVVCPWSTLLSEAGSLSFQDHSSHGEAAPFKAPELLQGQSDEE-RPDASRMHVYSLGMT
LYWSAGFHVPPDQPLQLR-EPLHSLLLTMCEDQPSRRLPLPAVLEACRLHQDDAAIYPAS
ANLHVRRLVSVVLGSGSEVGRKAVEE------SSSVQQDRSCQLRNRLHQASC-EGSVAP
ASDGLHPSKVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPGLSAS-----------------AHSRGSISVNSTLPAEAPQNL-----------
------------------------------------------------------------
--------------QEGWRLS---------------------------------------
----------SGS--APSVAAENSQPAT--PSQRAFVQRKGK---FSRP---EFVLLARE
APVTLHLPGSIV---TKKGKS-------YLALRDLCVVLLSGQSLEVKCDVTSTAGAIFN
AVVSFANLGELAYFGLAYMKGKEFFFLDPETRLCKIAPEGWSEQPRKKTSSDAFTLFLRI
KFF AGHCGL LQQSRTRHQFYLQLRKDILEEKLHCNDEMLLQLGVLA-------LQAEFGN
YPEE----QG--ESKAYFRVEDYVPASLIERMTAFRVQVEVSEMHRLSPMLWGEDAELEF
LRVTQQLPEYGVLV HRVLPEKTRPEG-ETALGICAKGVIVYEVKNNSRITTLRFQWREIW
KISTCRKKFTITSSITGKKHTFVTDSGKTCKYLLGLCSAQHGFNAKMSSP RQLS-SILYN
HDKHVQMANL-------------------------SLAH--LAQPKPLSWIQRLSRSE--
-----NTLFTP----RLEDATGGL--LRASLDDFTVETSKETGV-RGIGA-SPCTGRERL
--------------ESICLIQKPTTC-DPLSGPSVQST----------------------
---------------------------------C--TGPQNNRRKSFPAEPDGEIVH VTL
TRDPRRGFGFVINEGEDADEVDPGIFISSII-PGGPAEKAKKIKPGGQILALNRISLEGF
TFDMVVRMIQNSPDNIELI ISQSKGVCGNTPSKEKN-STARSGGFS--------------
---------------------------------------TDSL---TNGHQGGCSSRTPD
QERNTEELETALAQSSMPGRSP-QLSPLPL------------------------------
--KG--AGSSCPPSPSETNASEIYFVE LIKEDGTLGFSV--TGGVNTSVLYGGIYVKSIV
PGGPAAKEGQILRGDRLLQVDGVSLCGLTHRQAVQRLKGSGQVVRLV LERRGPRTAQQCP
SASDRMGDDCTAVSLATALPGRPASCVLATDGPTFE VTLRKNASGLGFSFTQMERARCSH
LKNDLVRINRLFPGQPAEENGAIAAGDIILAVNGRPTEGLVFQEVLHLLRGPSKEVTLLL
CRPPPGALPEMDQGWQIPVLSADKEFTRAAGSDSEQSPSLDQEDSQRDSASLDTGEGLGL
KPE-SFQKATREAQ---WDQ-DVERPLA-------TSLP-RRPQDSHPHLCRLHQELD--
------AAALPTSLEKDVRQNCYSVCDIRKLESFSC--------SSSLTRLSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLSLAAEQLLEDLRN-------DSS
DYVICPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQGQREDE-QSDASQMHVYSLGMT
LYWSAGFHVPPNQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACWVHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------SSCVQQNRSYLLRKRLHGTSS-ESPAAQ
ASECLHPCRVSEGS-TE------AQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-HSPEPHWSTS-----------------HSHCSLLVNR-TLPGADPQHQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFVLLAGE
APVTLHLPGSVV---TKKGKS-------YLALSDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFANLEELTYFGLAYMKGKEFFFLDNETRLCKIA PEGWREQPQKT-STNTFILFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLYCSEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPATLIERMTALRVQVEVSEMHWLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKKRP EE-EMALGICAKGVTVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSALHGFNAQM GSGPPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFTS----RLRDAAGGL--LSTSLDNFNVDTSKQAGT-EGTGR-RPCTGREQL
--------------KSACVIQNPTPW-DSLSGPLVQSM----------------------
---------------------------------H--AGSQNNRRKSFTAESGREILH VTL
KRDPHRGFGFVINEGEYSGQAHPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNTPNEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSHTED
QDRNIEELDMAGARSLVPRLRH-QLSFLPL------------------------------
--KG--PGSSCPLSPPEISAGEIYFVE LIKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQSARLV LERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGLKFE VKLKKNANGLGFSFVHLEKESFSH
LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEREWQTPELSADKEFTRATCTDSCTSPSLDQEDSWRDSASPDAGEGLGL
RPE-SSQKAIREAQ---WGQ-DRERPWA-------SSL--THSPKSHPHLCKLHQERD--
------ASTLATSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EGDMCHPYG
AH----------------SPTLEVEEYPTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTIPLPQFCSWG--TIPE-SLPPEEY
QESGSEWEDLEETVDLE--DAALRS----LS------------FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

LQPISFSESMSVASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRN-------DSS
DYVVCPWSLLLSAAGSLSFQDNVSHIEAAPFKAPELLQGPDEEE-RPDASQTHVYSLGMT
---------------------------AMCEDQPRRRRPLQAVLEACRIHQEEVAVYPAP
ASLHISRLVGLVLGTISEVERRVAEE------NACEQRNRSCFLRSRLHQADS-ESPGSR
APDALQPRRVSGRS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLERCWSTT-----------------AHSRSG-F-NSTFAGAGPCDC-----------
------------------------------------------------------------
--------------EEGPRCG---------------------------------------
----------SGP--MLLAEAESSKPAT--SSPRNFLHRKGK---FSRP---EFILLAAE
APVTLHLPGSIV---TKKGKS-------YLALRDLRVLLLNGQCLEVKCDVESTAGAVFN
AVMSFANLGETTYFGLAYVKGEEFFFLEPNTRLCKVA PEGWREQQPKS-SVDTLTLFLRI
KFFVSHYGL LRHSLTRHQFYLQLRKDILEERLYCNDETLLQLGVLA-------LQAEFGS
YPKE----QV--EGETYFQIQDYIPARLIERMTAIRVQVEVSEMHRLSPAPQGEDAELEF
LEVVQQLPEYGVLV HRVSPAKKR QEG-GMALGICTKGIIVYEVKGSRRTTTFQFPWRETG
MISTHRRKLTVTSSTTGKKYTFVTDSAKTCKYLLGLCSSQHWFNAHMGLEQPPHLL----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

---------MSQSSVTLASILQVKGEPLSEEEMWSLLFLATEQILEDLNK-------GSS
NYVVCPWSTLLHATGSLSFQDNVSFIEATPFKAPEILQGQGQNL-QLEISKVHVYSLGMT
LYWSAEFRVPPNQPLQLS-KPLLSILLMMCEDLPQKRASLPLIWEACFLYQQEAAVSL--
TQLHIKRLVSLVLGSITEMEQIVVEE------SKFVQQNRSYMIRRRLHQKQSELS-LLS
TLKTLDXXXXXXXXXXX-------XXXXX---------------X---------------
------XXX---------X-------------------------------X---------
---------------------------------------------------X----X---
---------XXX------------------XXXXXXXXXX-X------------------
X--XXX---------------XX-------------XX--XXXX------X------XX-
-XXXX------------XXXX-------------X-------------------------
-X--XXXXXXXXXX------XXX-----X--------------------------XXXXX
XXXXXXXXXXXXXXXTKKGKS-------YLSQRELYVVLLNGQCLEVKCDIKSKARDVFN
LVRNYANLVEYFYFGLACQKGKEFFFLNDETKLYEVAPEGWNQI--QKTTIVNFTLFLRI
KFFVSHFHLIQHSLTRHQFYLQLRKDILEERIYCNDEMLLRLGALA-------LQVEFGN
YSPE-----A--QGKHYFLVEDYIPASMIERMTPSCVQLEISKMHRCHGPLSGEEVELEF
LKLTQKLPEYGVFFYEVFQEKKVPEA-EMNLGICAKGIIVYEVKNNNRIASLRFQWQEIG
KISTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXXXXXXX
XXX--------XXX---XXX-------------XXXXXXXXXX---XXXXXXXXXXXX--
-----XXXXXX----XXXXX-XXX--XXX--XXXXXXXXX-XXXXXXXXXXX--------
-----------------XXX--------XXXXXXXXXXXXXXX-XX--------------
---------------XXXXXXXXXXXXXXXXXXXXXXXSQNPQRENYLTGLEREIICVTL
KRDPEHGFXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXGRIISLNSISLEGA
TFNMAVKMIQNFPDKVDLIVSQPKXXXXXXXXXXXX-XXXXXXXXXXXXXX---------
-----------------------------------------XXXX--XXXXXXXXX---X
XXX------XXXXX--XX----------------------------XXXXXXXXXXXXXX
XXXXXDPDSAHPSPPAKINTRETYWVELVKENGTFGISV--TGGINTSVRYGGIYVKSIV
PGGPAAKEGQIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXX-XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXTPTTSPDKEFTRAECYSRT-RSNLNPGNSEDSSSLESEEDVSSK
T--VSFHKTI--DKEEWGSEEGEERPWVTLL---------SHPDVSHDCSWSHHQETA--
------VPELVSPLEEDLRQNCYSVCDIKTPE----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

VCHIRVIAGMSPASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRK-------DSS
DYVVCPWSALLSAAGSLSFQDHISPIAAVPFKAPELLQGQSDEE-LSDASQMHVYSLGMT
LYWSAGFHVPQDQPLRLH-EPLHSILLTMCEDQPHRRLPLQSVLEACRVHREEVAVYPAS
ANLHVQRLAGLVLGTISEVGRGAAEG------SYSVQWDRSRLIRSRLHQVSC-ESPAAG
TLERPHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPGPSTS-----------------VPSHCSLSASSALPMEAPPEL-----------
------------------------------------------------------------
--------------EDGQQLS---------------------------------------
----------SGS--MFPVSAETSQSAI--PSQRAFLQRKGK---FSRP---EFILLAGE
VPVTLHLPGSVV---TKKGKS-------YLALRDLCVVLLSGQRLEVKCDIMSTAGAVFS
AVMSFVHLGELTYFGLAYMKGKEFFFLDNETRLCKIAPKGWSEQPQKKTFSNTFTLFLRI
KFF VSCCLQ LQHSQTRHQFYLQLRKDILEEKLYCNDETLLQLAVLA-------LQAEFGN
YPEE----QI--ESKTYFRVEDYLPASLLERMTALRVQAEVSERHRVSPVLWGEDAELEF
LRVTQQLPEYGVLV HRVLPEKARVEG -EMALGICTKGVIVYEVTNNSRIATLRFQWREIR
KISTCRKKFTITSSITGKKHTFVTDSAKTCKYLLRLCSAQHGFNAQM SSLP-VA-AVISD
HDKCVQMPSM-------------------------SLAH--LAQSKSLTWIQRLSSSE--
-----NALFAPAP--RLEAAAGGL--LAASMDNFTVKNSKETAA-RGNRG-SPCMRREQL
--------------ETISLIQKSTTR-DPVSGLPVESM----------------------
---------------------------------Y-MVGPQNDRRKGFIAEPEGEITH VTL
TRDPHRGFGFVINEGDGVGKADPGIFISSII-PGGPADKAKKIKPGGRILALNHISLEGF
TFDMAVRMIQNSPDSIELI ISQSKGFCGSTPSEEKN-SMANSGVLS--------------
---------------------------------------TDSP---SNWHQGSFSSHKQN
QEKNIEDLEVAQTQSLLPRVRP-QLSPSPL------------------------------
--KGQGTGSSYPPPPSEINVSEIYFV KLVKEDGTLGFSV--TGGINTSVPYGGIYVKAIV
PGGPAAKEGQILRGDRLLQVDGVSLCGLTHKQAVCCLKGCGQVARLV LERRGPRTAQQCP
SAKDRTGDECTAVSLATVLPGRPEGCVSATDGPKF EVTLKKNASGLGFSFVQMERESCSH
LKNDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRPIEGLVFQEVLHLLRGASQEVTLLL
CRPPPGVLPEVDQGWQTPVLSSDKEFTKASCTDSEQSPSLDQEDSRRDSASPDAGESLSL
RPE-SFQKAPGEAQ---GDQ-DLERPWT-------TCL--THPQDSHPHLCRLQQEMD--
------ASTLATSLEKDMRQNCYSVCDIKRLERFSS--------SSSLTGLSTDIS----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--------MWHPASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLCD-------DSS
NYVVCPWSVLLSPTGSLSFQDHVSHIEAAPFKAPELLQGQSGDE-QHDASQMHVYSLGLT
LYWSAGFHVPPNQPLQLC-QPLHSILLTMCEDQPGRRLPLQSVLEACQIHWEEAAVHPTS
ANLHVRQLVGLVLGTISEVERRAVEE------SSSGQRDRSHLLRNRLHRASC-ESQAAW
ALGCPRHCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPGLNTS-----------------AHGRCSVAVNSALPTQDPPDL-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--ALP---ENSRPAT--PSQRSFLQRKGK---FSRP---EFALMAGE
APVTLYLPGSIV---TKKAKS-------YLALRGLCVVLLSGQCLEVKCDVTSTVGAVFS
AIAPFASLGELTYFGLAYLKGKEFFFLDAETRLCKIA PEGWSEQPQKKSSPNTFVLFLRI
KFFVSHYGL LQHSWTRHQFYLQLRKDILEEKLYCNDETLLQLGVLA-------LQAEFGS
YPEE----QV--ESKAYFRVEDYVPASLIERMTALRVQVEVSEMHRLSPVLWGEDAELEF
LRVAQQLPEYGVLV YQVLPEKTRLEG -EMALGICAKGVIVYEVRNNSRIATSRFQWREIE
KILAYRKKFIITSSVTGKKHVFVADSVKTCKYLLGLCCAQHGFNAQMS SPGVT-----SD
SNKCVQMGSL-------------------------SLAH--LPQSNQLTWIQRLSCSE--
-----NALFIP----GLEDAAGGL--LRRSLDNFTMDTSKGTGA-QGLRG-SPCLGREQL
--------------ERLCLIQKPTTC-DPLSRQPAQST----------------------
---------------------------------R--TGSRNNRRRSFIAEPDGEIVH VTL
SRDPHRGFGFVINEGEDVGKVDPGIFISSII-PGGPAEKAKKIKPGGQILALNHISLEGF
TFDMAVRMIQNSPDTIELI ISQSKGVCGNTSSEEKN-SAANSGVFS--------------
---------------------------------------TDSL---SDGPRGSFSSHTQD
RERNIEELEVAQTQSVMPRLRP-QLSALPF------------------------------
--KG--AGSFCPPSPSETTASEIYFVE LVKEDGTLGFSV--TGGINTSVFCGGIYVKSIV
PGGPAAKEGRILQGDRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLV LERRGPRIAQQCP
SANDRMGEECTAVSLATVSPGRPASSVSATDGPKFE VKLKKNASGLGFSFVQMESEHCGH
LKNGLVMVKRLFPGQPAEENGAIAVGDIILAVNGRSTEGLDFQEVLHLLRGASQQVTLLL
CRPPPGALPEMDQGWQTPVLVEDKEFPRAACADLEQSPSLDQGDSRRDSASPDTGEGLGL
RPE-SFQQATQEAQ---RDQ-DTERPWA-------TSL--TDPRDSFPHLCRLHQEME--
------ASALATSLEKDLRQNCDSVCDIGRLGSPEL--------YSDNEERDMHHPP--G
TL----------------SPTSEDGVYLTIN-----------------------------
-----------------PSLGDRLPCGECLEAGSGTIPLPQFCFWG--SFSQ-SLPPG--
--SDSEWEDIEEAEDTD--DGPL-R----WVA--L---W----VE---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTRDTGMSPASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLCD-------DSS
NYVVCPWSVLLSPTGSLSFQDHVSHIEAAPFKAPELLQGQSGDE-QHDASQMHVYSLGLT
LYWSAGFHVPPNQPLQLC-QRLHSILLTMCEDQPGRRLPPQSVLEACQIHWEEAAVHPTS
ASLLVRQLVGLVLGTISEVERRAVEE------SSSGQRDRSHLLRNRLHRASC-ESQAAW
ALGCPRRCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPGLNPS-----------------AHGRCSVAVSSALPAQVPPDL-----------
------------------------------------------------------------
--------------QEARRLS---------------------------------------
----------SGS--ALP---ENSRPAT--PSQRGFLRRKGK---FPRP---EFALMAGE
APVTLYLPGSIV---TKKAKS-------YLALRGLCVVLLSGQCLEVKCDVTSTVGAVFS
AIAPFANLGELTYFGLAYLKGKEFFFLDAETRLCKIAPEGWSEQPQKKSSPNTFVLFLRI
KFF VSHYGL LQHSWTRHQFYLQLRKDILEEKLYCNDETLLQLGVLA-------LQAEFGS
YPEE-----V--ESKAYFRVEDYVPASLIERMTALRVQVEVSEMHRLSPVLWGEDAELEF
LRVAQQLPEYGVLV YRVLPEKTRPEG -EMALGICAKGVIAYEVRNNSRVATSRFQWREIE
KILAYRKKFIITSSVTGKKHAFVTDSVKTCKYLLGLCCAQHGFNAQMS SPGVT-----SD
SDKCVQMGSL-------------------------SLAH--LPQSNQLTWIQRLSCSE--
-----NALFIP----GLEDAAGGL--LRRSLDNFTMDTSKRTGA-QGLRG-SPCLGREQL
--------------ERLCLIQKPTTC-DPLSGQPAQST----------------------
---------------------------------R--TGSRNNRRRSFIAEPDGEIVH VTL
SRDPHRGFGFVINEGEDVGKVDPGIFISSII-PGGPAEKAKKIKPGAQILALNHISLEGF
TFDMAVRMIQNSPDTIELI ISQSKGVCGNTSSEEKN-STANSGVFS--------------
---------------------------------------TDSL---SDGPRGSFSSHTQD
RERNTEELEVPQTQSVMPRLRP-QLSALPF------------------------------
--KG--AGSSCPPSPSETTASEIYFMEL VKEDGTLGFSV--TGGINTSVFCGGIYVKSIV
PGGPAAKEGRILQGDRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLV LERRGPRIAQQCP
SANDRMGEECAAVSLATVSPGRPASSVSATDGPKFE VKLKKNASGLGFSFVQMESEHCGH
LKNGLVMVKRLFPGQPAEENGAIAVGDIILAVNGRSTEGLDFQEVLHLLRGASQEVTLLL
CRPPPGALPEMDQGWQTPVLVEDKEFPRAACTDLEQSPSLDQGDSRRDSASPDTGEGLGL
RPE-SFQQATQEAQ---WDQ-DTERPWA-------TSL--TDPRDSFPHLRRLHQEME--
------ASALATSLEKDLRQNCDSVCDIGRLGSLCL--------QECP------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--MHVFIVGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVICPWSALLSATGSLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDVSQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
ASLHIRKLAGLVLGTISEVEKRVVEE------NSSVQQNRSYLLRKRLHGTSS-ESPEAQ
ASECLHPRRVSEKS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPHWSTS-----------------THSHCSLLVNRALSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VHSA-ADSSWPTT--PSQRIFLQRRSK---FSRP---EFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-STNTFTLFLRI
KFFVSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTVLRVQVEVSEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQTANL-------------------------SPAH--QVQSKPLIWIQRLSCSE--
-----NELFAS----KLQDAVGGM--LSTSLDNFNVDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSV----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKCT-IFPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSYTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANDSMGEEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPEAGEGLGL
RPE-SSQKAIRAVQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EDDMYHPCG
AP----------------SPTSEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTILLPQFCSWG--TVPE-SLPPEES
PESGSEWEDLEEPVDLE--YGALRW------S--L---S----FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

---------MSVASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRN-------DSS
DYVVCPWSLLLSAAGGLSFQDHVSHIEAAPFKAPELLQGSNEEG-QPDASQMHVYSLGMT
LYWSAGFRVPPNQPLQLQ-EPVHSLLLAMCEDQPRRRRPLQAVLEACRIHQEEVAVYPAP
ASLHISRLVGLVLGTISEVERRVVEE------NTCEQQNRSCFLRSRLHQADS-KSPGAP
ASDALQPRRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLERCWSTT-----------------AHSRNS-SVNSTFAGAGPCDC-----------
------------------------------------------------------------
--------------EESPWCG---------------------------------------
----------SEP--MLLAEAESSQPAT--SSPRNFLQRKGK---FSRP---EFILLAGE
APVTLHLPGSIV---TKKGKS-------YLALRDLCVVLLNGRCLEVKCDMESTAGAVFK
AVMSFANLGETTYFGLAYVKGEEFFFLDKDTRLCKVA PEGWREQHPKG-SVDTFTLFLRI
RFFASHYGL LRHSLTRHQFYLQLRRDILEERLYCNDETLLQLGVLA-------LQAEFGS
YPKE----QV--EGKAYFRIQDYIPARLIERMTAIRVQVEVSEMHRLSSAPWGEDAELEF
LEIVQQLPEYGVLV HRVSPEKKRP EG-KMALGVCTKGIIVYEVRGSRRIATTQFPWRETG
MISTHRKKLTITSSTTGKKYTFVTDSSKTCKYLLGLCSSQHWFNAQT GSKHPSHRFTG--
QDKFAQIASL-------------------------SSAH--QTQAKPITWIQKLSCSE--
-----NELCVP----RLQDATGGQ--LGTSMENKQ--GFKEPGM-ERIGS-SPYPGGEQL
--------------HSIGLNQKPAQT---AFGTAGHSMCAGSNCLGRRT-----------
---------------QI-------------CCFDSVSGSQNSKRKGFFGEPNQDIVCV ML
KRDPVHGFGFVINEGEDAEQTRPGIFISSLI-PGGPAERAKKIKPGGKILALNHISLEGF
TFSMAVRMIQNSPDDMELI ISQPKGVCGTSHSEEKN-STASSGMFC--------------
---------------------------------------TDIL---SNRCQGRQSPQIHD
QDRNVRGPETAQ------------------------------------------------
------GAGSCPPSPLQTNTGEIYFVE LVKEDGTLGFSV--TGGINTSVPHGGIYVKSII
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV LERRGPRAAPQCP
SADDRMGDVHMAVSLVTARPGRPASSVSVTDGPKFE VKLKKNSRGLGFSFVHMERGNCIH
TKSDLVRIKRLFPGQPAEEHGAIAAGDIILAVNGKPIEGLAFQEVLHLLRGAPEEVTLLL
CRPPPGILPEMEPGWQTPELSGDQRLTMATCAGSEQSPSLDQEDNWRDSTSLDAGEGLSP
RPE-SSFKDVRQVK---GDR-EKERPWA-------KSW--MHPMESHPHVCKLHPEPE--
------TPALATSLEKDMRQNCYSVCDIRRLGRFSF--------SSSLTRLATDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

SLPDPRDLGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSATGSLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
ASLHIRKLAGLVLGTISEVEKRVVEE------SSCVQQNRSYLLRKRLHGTSS-ESPAAQ
ASECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPDPHWSTS-----------------THSHCSLLVNRALSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--PSQKGFLQRRSK---FSRP---EFILLAGE
APTTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQRLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIAPEGWREQPQKT-STNTFTLFLRI
KFF VSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHIEDYIPASLIERMTALRVQVEISEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFAEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQ MGSGQPSHVLFDPD
HDKFVQMANS-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAVGGL--LSTSLDNFNVDGSKEAGA-EGIGRSSPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSV----------------------
---------------------------------Y--AGSQNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSHTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARLV LERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSTDKEFTRATCTDSCTSPILDQEDSWRDSASPEAGEGLSL
RPE-SSQKAIRAAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIMRLGRYSF--------SSSLTRPSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MRPLAKDTGMSVASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRN-------DSS
DYVVCPWSLLLSAAGGLSFQDHVSHIEAAPFKAPELLQGSNEEG-QPDASQMHVYSLGMT
LYWSAGFRVPPNQPLQLQ-EPVHSLLLAMCEDQPRRRQPLQAVLEACRIHQEEVAVYPAP
ASLHISRLVGLVLGTISEVERRVVEE------NACEQRNRSCSLRSRLHQADG-ESPGAP
ASDALQPRRVSERS-AE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLERCT--------------------AHSRNS-FVNSTFAGAGPCDC-----------
------------------------------------------------------------
--------------EESPWYG---------------------------------------
----------SEP--MLLAEAESSQPAT--SSPRNFLQRKGK---FSRP---EFILLAGE
APVTLHLPGSIV---TKKGKS-------YLALRDLCVVLLNGRCLEVKCDMESTAGAVFN
AVMSFANLEETTYFGLAYVEGEEFFFLDKDTRLCKVA PEGWREQHPKG-SVDTFTLFLRI
RFFVGHYRL LRHSLTRHQFYLQLRKDILEERLYCNDETLLQLGVLA-------LQAEFGS
YPKE----QV--EGKAYFRIQDYIPARLIERMTAIRVQVEVSEMHRLSSAPWGEDAELEF
LEIVQQLPEYGVLV HRVSPEKKRP EG-KMALGVCTKGIIVYEVRGSRRIATSQFPWRETG
MISTHRKKLTITSSTTGKKYTFVTNSSKTCKYLLGLCSSQHWFNAQT GSKHPSHRFTG--
QDKFAQIASL-------------------------SSAH--QTQANPITWIQKLSCSE--
-----NELCVP----RLQDATGGQ--LGTSMENKQ--GFKEPGK-ERIGS-SPYTGGEQL
--------------HSIGLNQKPAQT---VFGTAGHSMCAGSNCLGRRT-----------
---------------QI-------------CCFDSVSGSQNSKRKGLFGEPNQDIVCV ML
KRDPVHGFGFVINEGEDAEQTRSGIFISSLI-PGGPAERAKKIKPGGKILALNHISLEGF
TFSMAVRMIQNSPDDMELI ISQPKGVCGTIHSEEKN-STASSGMFC--------------
---------------------------------------TDIL---SNRCQGRQSPHIHD
QDRSVRGTEMAQ------------------------------------------------
------GAGSCPPSPLQTNTGEIYFVE LVKEDGTLGFSV--TGGINTSVPHGGIYVKSII
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV LERRGPRAAPQCP
SADDRMGDVHMAVSLVTARPGRPASSVSVTDGPKFE VKLKKNSRGLGFSFVQMERGNCIH
TKSDLVRIKRLFPGQPAEEHGAIAAGDIILAVNGKPIEGLAFQEVLHLLRGAPEEVTLLL
CRPPPGILPEMEPGWQTPELSGDQRLTMATCAGSEQSPSLDQEDNWRDSTSLDAGEGLSP
GPE-SSYKDVRQVK---GDR-EKERPWA-------KSW--MHPMESHPHVCKLHPEPE--
------TPALATSLEKDMRQNCYSVCDIRRLGSLEL--------DRDGADGATCFLP--E
SS----------------SLTVDYEEYLTLT-----------------------------
-----------------SASAGQLPCEECLEADSETIPLPQFCSLG--ALLK-SSLPEES
QGSESDWEDLDEPVDRD--E-VLRW----TRS--ARQPL----AAEP-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--------------ATLAEVLWAKGSPLEEEDIWALLYLSTLQLLEDLHKGEM---KNPA
ICVICPWSVVLSAEGNLSFQNNASQTEAIPFSAPELLHRQNKNQ-RIGLTKMLVYSLGMT
LYWSADYQVPPNQSLQLS-DQLHSLLLTLCEDLPHKRLSPESVLEVCEAHQKESSSLP--
ANIYIKKMVQFVLESVSEVERVATED------STTSQLNRSHVIRKRLHEKIPDTS-PLF
SQMNFHQGKKSLGLGQ------DKGSRLM--NYSRSTEDYRQLSV-----DYSDTNSISE
STSLILSNRGHRRGK---IFLLDFFLPVSYQAAPSPLSCFMPLCQMKLFSRSQTKPDSMF
LPPGVLKQMRHH----------------------------AATPRRWQYQDSSTEENKEV
EQPLTPLFQRRE------------------SLCDNLIQSSLNQISEWDKEMLILYL----
APKLNE---GEKFYKSYLLITQI-----LSDS---YLSCPAHFQKPAKTPLLPSKSFLEN
LLVPYVRQPTENKKQRNRNYS-KPARSGSPNEEKS---------V---SAVEEIP----G
GTHRNSRHNLLSLGSTFSVSTKDY--TAAATSQKCLFQRKEKVTNFSGP---EFIILSSE
PPVTLQLPGSIV---TKKGKS-------YLSQRDLNVILLNGQCLEVQCDIKSKARDVFN
TVVAYASLVEHSYFGLAYLKGKEFFFLDDETKLYKVAPDGWNDQPKKKTSIINFTLFLRI
KFFVSHFSVIQHSLTRHQFYLQLRKDILEERLYCNDETALKLGALA-------LQAELGN
YASE-----V--HGKSYFRVEDYIPASRIEKMTLAHVQRELAKLHRMNRSLFEDEAELEF
LKVTQQLPEYGVLFYRVSQEKKGTGG-DIILGICAKGIIVYEVKNHTRIASLRFQWRETE
RISAHRKKFMIESSFSGKKHTFITDTAKTCKYLLDLCSAQHKFNAQMNSRQLRQTSSVVT
QKMF-HTKNINSG----VQLFSSCFAMSVGGTTITSLDFRF-----STVLIQSSSQPRTG
CPQHALCRWPA----KLHNCVTDSEAQCTCCPKRKCSM---KAVTSSSSQCCLCHHREST
EDGIMSVDLSFPPLPISLLIQRKLIQ-KSKSGLGLLCANDSVHRHKSNSLTEAVEQGKQH
ENQGHLYKNLQLRYTTQQMLHES----IDSEVMVML--KEITKMYSIVDAPEREIICVSL
KRDPKNGFGFVIIGGENVGKLDLGIFIASII-PGGPADRAGNIKPGGRLISVNNISLEGV
SFNTAVKIIQNSPDEVELII SQPKVMKQIHFSICKT-T---VLHFTMANSFYGSYNSLIW
EVI--SPSCDGFADIYEEGLNEEKSISRGNSTSGSEISCVDSGRKKIQDCRAALPK---E
QAVNIDELEKALSWSLAPKLGP-RIPVLSADSLDVEVVEIVMMSEKM----------EEL
LHKIQEADSSHLQPPAETSSNETY TVELVKEDGTFGISV--TGGINTSVPHGGIYVKSII
PRGPADKDGQIKIGDRLLEVDGISLCGLTHKQAVENLKKSGQVAKLVL ERGHHQEAEPCL
STNDRKKDQCAMVSVATSFTDGSKDYCFLTDENTF EVKLTKNSGGLGFSVLQMEEEGYEY
LGGAIVRIKRLFPGQPAEENGEIEVGDIILAVNGKSLQGLLYQDVLHLLRGAPSEVTLLL
CRPPKGVLPEIEQTVLTPAPSPVKVFMEEMPGSPEAGNSLDPSTSDGGSTSQDLEDSLDS
PLAADFSEPPDENFESKLLRVKPRQPFNTITSMLLKIMMCISSRFSSGHLIKDMEENSST
TISLFSSPVFYKSDGDISNRNCMSEILSLTP-IDEEYLTISSTPVTSLSRGGSSETLSTT
LVTPQPRICGPFLSSLPARDTQEMEV FVTLTRSENNGYGFSVVLNKVDNCLYVDEILHEP
ALSDGRLRRGDRIIMVNGIDVTSLQCNEALSLLQSSPPDLHLVV GRAGSDPCPSVRP---
-------DDIP EITLTKGANGQLGLKLTGGAGSKLQGIYVLEIVPGSPASVEGSLQPRDQ
----ILYICGLWTEGISLDDAVRVCEAATQNVQIKA TRNGNPVVPIEQENSNISVKNLK-
------RNEKHLKETNCEAQQSTPNSPECKVRGNFIKHEVFHQVKCAIYKILGKIN-MKV
MTEVSGTARQGLSEDTGKGMVIHSYLDESEVNKNRLLSSSSNSNDRSVERSLEAQSVFTL
KEESNWMCSKKEPLXLPHTERLKTKRSQKYAGYEGCRRESQQSESDSWNNEDDDMSHRTS
ILPRTMTQ-------------------------------------NSNSGRTFVSEDELT
HLINFKSSPTRVCPRTGIRHFVQGLKSRIENQEVLKEFMALEHVKPIDDCRTGKAPE NQD
KNRYQDILPYDKTRVPLGENNGYINASYIRMKVGEEEHFYIITQGPLPSTIADFWQMVWE
SESDLIAMMTKEVELGKVKSHRYWPEPPHDSIDLANFHLRLDSYQILEYFVIRIIEIINK
QTDERRIVSHLQFTTWPDHSSAKLSEQLVKFICYMRKAHRRGPVVAHCSAGIGRSGVLLC
VEILLSYIEKDLCFNIKHIVRDLREQRFGMIQSKDQYLFCYEFVLQVLQNLQA

------------------------------------------------------------
-----PWSALLSAAGSLSFQAHVSH-EAAPFKAPERLQGCDEEE-EPEAAQVSVQGSGKT
C---AGLGAPAPSA-TLA-SLVLNGLKTVVPRLPFRQVIINLQKEVCQSHRSSSSIYPKI
ARSSKRQFLGLILKRGNSKEIKKAGTQHWAGCPVGVEAGLLFLLPQRLQEKA-----VTT
PSEHTHPCPLLRRA-QR------PP-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSWEPSSSAS-----------------GHTHCSPFANRSRPHSISR-------------
------------------------------------------------------------
--------------QRGHIFG---------------------------------------
----------SQSGSTMAA-EEYWILHTDAPYPRPLVERRSS---SPGP---ESVLLAAE
APVTLHLPSSVV---TKIGGCRDRQRNPCLALETLHVALLNGWRLEVTCDVGSAVGAVFH
VVTSF-DLGELTYFGLAYVKNNEFFFLDKETRLCKIAPEGWSNSRRKQ-PAVNFALFLRI
KVSVSPLGL LQHSLTRHQFYLQLRKDILEETLYCHCETLLQLGPSPCKASRAVILRSFGR
YKDE----QVKAERKASFRVEGYLPASLIRGTMGL-QRVDVSEMRRGARALSGAEAELEF
LQVAQRHPDYGVLV HQVFPEKTRM GR-EVALGTCAKGIIVYQVRNASRIASLQFQWREIG
KASTHRKKFSITSSVTGKKHM-VTAPAGTCKYFLDLRSAQQGFTARMGSRQPPRLVGPAS
FQA--QTSKS-------------------------SPTPQDQVQD--------RRATS--
-----CCLYSPAWSRRPRGAEGSS--LPRPALHVPDAFNLDSGG-EGVRG-SPSTGQGQL
--------------QSTCSIQKPRTS-ASLCGPPALNGS---------------------
--------------------------------------PANTWSRQLSLSPTSSASAVAP
--GGRRG-----AESSAVG-KPPGHFSMCAVSIGAPTPRLS---PPW---SSESPSVTGR
KRCAPRRATQ----LLTSSWLVFIGVCEHTPNKEMNNGTANAGICI--------------
---------------------------------------MNGP---GDGNQGCFLSHTQD
QERNIEEAEKAQAQSSVPRPAP-PLSPLPV------------------------------
--KS--AGSSHLPSPSETNAGEIYFVELVKEDGTLGFSV--TGGMTTRV----LYVKSII
PGGPAAREGQILQGDRLLQVDGTSMCGLTHRQAVPGLKGSGQIARLVLERRGPRTAQQRP
SANDRMGDVRSAVSLVTTLPGRPTSCVSATDGERFEIKLKKNSSGLGLSCEQMESESCCV
PGNSLLRMERLFPGQPAEENGALGAGDVTLAVNGRSPRGLGFSCVLVSCVVGP-EKLVLA
CRPPSRTRPKGENGFKTSALWVGKESPRKTCPASERCSSRDGDGSQAGGTSPVAEQVLAL
GPE-SFQRATREST-------HREKPRA-------PSS--TRHQDSLPHLHGPHRELD--
------AR-RATSLEKDVRQNCCSVCDVRRLDR---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQSLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLSLAAEQLLEDLRN-------DSL
DYVICPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQGKSADE-QSDASQMHVYSLGMT
LYWSAGFHVPPNQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------SSCVQQNRSYLLRKRLHGTSS-DSPAAQ
APECLHPCRVSEGS-TE------AQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-HSPEPRWSTS-----------------HSHCSLLVNC-TLPGADPQHQ-----------
------------------------------------------------------------
--------------QEDRRLS---------------------------------------
----------SGS--VYSA-VDSSWPTT--PSQRGFLQRRSK---FSRP---EFVLLAGE
APVTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQRLEVKCDVESTVGAVFN
AVTSFASLEELTYFGLAYMKGKEFFFLDHETRLCKIA PEGWREQPQKT-STNTFLLFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLYCSEETLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERTTALRVQVEVSEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQIFSEKKRP EE-EMALGICAKGVTVYEVKNNSRIATLQFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCLAQHGFNAQM GSGPPSHVLFD--
HDKFVQMANL-------------------------NPAH--QAQSKPLIWIQRLSCSE--
-----NELFTS----RLRDAAGGL--LSTSLDNFNVDTSKEAGA-EGIGR-SSCTGREQL
--------------KSACVIQKPTPW-ESLSGPLVQSM----------------------
---------------------------------Q--AGSQNNRRKSFIAEPGREIVH VTL
KRDPRRGFGFVINEGEYSGQADPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNTPNEEKN-STANSVVSS--------------
---------------------------------------ADIL---SFGYQGSLLSHTQD
QDRNIEELDMAGVQSLVPRLRH-QLSFLPL------------------------------
--KG--PGSSCPLSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPEQVARLV LERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGLKFE VKLKKNANGLGFSFVHLEKESCSH
LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPEFSADKEFTRATCTDSCTSPSLDQEDSWRDSASPDAGESLSL
RPE-SSQKAIREAQ---WGQ-DRERPWA-------SSL--THSPESHPHLCKLHQERD--
------TSTLATSLEKDVRQNCYSVCDIVRLGSPEL--------DGEDG--EGDMCHPHG
AH----------------SPTLEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTIPLPQFCSWG--TVPE-SLPPEES
QESGSEWEDLEETVDLE--DAALRS----LS------------FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDAGMSLSSVTLASALQVKGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSAAGSLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLH-EPLHSILLTMCEDQPHRRCTLQSVLEACRIHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPVAQ
APECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPHWNTL-----------------THSHCSLLVNRTLPGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VHSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKT-SMNTFTLFLRI
KFF VSHYEL LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALQVQVEVSEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-EMALGICAKGVIVYEVKNNSRIATLRFQWRETR
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQ MGSGQPSHVLFD--
HDKFVQTANL-------------------------SPAY--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAAGGL--LSTSLDNFNVDGSKEAGP-EGIGR-SPCTGREQL
--------------KSACVIQRPMTW-DSLSGPPVQSM----------------------
---------------------------------H--AGSKNNRRKSFTAEPGQEIVC VTL
KRDPHRGFGFVINEGEYSGQADPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQSSPENIELIISQSK------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---G--AGSSCPPTPPEIGAGEIYFVELVKEDGTLGFSV--T------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQALTKDTGMSLSSVTLASALQVRGEALSEDEIWSLLSLAAEQLLEDLRN-------DSS
DYVVCPWSVLLSATGSLSFQGHVSHIEAAPFKAPELLQGQSDDG-QADASQMHVYSLGMT
LYWSAGFHVPPNQPLQLC-EPLHSILLTMCEDQPCRRRPLQSVLETCHVHEKEVAVYPAP
ASLHIRRLVGLVLGTISEAERRVVEE------SASVLQNRSYLLRKRLHGTSH-GSPAAQ
ALAGPHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPHSSAS-----------------AHSHCSLFANRSIPGADPQDP-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--AHSV-TESSWPTT--P-QRGFLQRKGK---FSRP---EFVLRAGE
APVTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGKRLEVKCDIESTVGAVFN
AVMSFANLGEFTYFALACMKGKEFFFLENETRLCKIA PEGWSEQPQKT-SMNTFTLFLRI
KFFISHYGL LQHSLTRHQFYLQLRKDILEERLYCNEETLLQLGVLA-------LQAEFGN
YPKE----QV--ESKAYFRVEDYIPASLIERMTAFRVQVEVAEMHRLISAVLGEDAELEF
LRITQQLPEYGVLV HQVYPEKKRP EE-EMALGICAKGIIVYEVKNNSRIATLRFQWRETR
KISTYQKKFTITSSVTGKKHTFVTDSAKNCKYLLGLCSAQHGFNAQMS SGQSPQVLTD--
RDKFVQMANL-------------------------SPAH--QVQSKPLIWIQRLSHSE--
-----NELLAP----RLQGAAGGL--LSTSLDNFNVETSKESGA-EALGG-SRNTGREQL
--------------ESTCLIQKPTTG-DPLFGLPVQSM----------------------
---------------------------------H--AGLQNNRGRSFTAEPGQEIVH VAL
KRDPHRGFGFVINEGEYVVQDGTGIFISSII-PGGPAEKAKKIKPGGQILALNNISLEGF
TFNMAVRMIQNSPDNIELTISQSR------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTQDTGMNPASVTLASALRVKGEALSEEEIWSLLSLAAEHLLEDLRK-------GSS
DYVVCPCSTLLSASGSLSFQSHISHIEAALFKAPELLQQQNDDE-QLDASQAHVYSLGTT
LYWSAGFHVPPNQSLQLL-EPLHSVLLTMCEDQPHRRLPLQSVLEACQVHR-EVAVYPAS
ANLHIKRLVGLVLGTISEVERRVMDE------SSSVQQDRSYFLRNRLHQACC-ESPVAR
ALERLHPCGVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPGPSTS-----------------ALGHCNFSVNSALPAEAPQDL-----------
------------------------------------------------------------
--------------QEGRQPS---------------------------------------
----------SGS--TLSMAVQNSQPTT--PSQKHFLQRKGK---FSRP---EFILLAGE
APVTLHLPGSIV---TKKGKS-------CLTLRDLCVILLSGQCLEVKCDITSTVGAVFN
AVMSFTNLGELTYFGLAYLKGKEFFFLDNQIRLCKIAPEGWSEQPQKT-SSRAFTLFLRI
KFYVSHYGLLQQSWTRHQFYLQLRKDILEEKMYCNDEMLLQLGVLA-------LQAEFGS
YPEE----QV--ERKAYFRVEDYIPASLIERMTALRVQVQVSEMHRLSPVLCEEDAELEF
LRVTQQLPEYGVLVYQVLPEKTRPEG-EMALGICAKGVIIYEVKNNSRIATLRFQWREIG
KISTYRKKFTITSSITGKKHTFVTDSAKTCKYLLGLCSAQHSFNAQMNAPRVA-----SD
YNKCVQMVNM-------------------------SRSY--LAQSKPLTWIQRLSCSE--
-----NVLFTP----RQKDTVGGL--LCTSLDNFTMDTSRETGA-LAVSG-SPSTGQEQL
--------------ENICLIQKPMTC-GPFSGQSIQSM----------------------
---------------------------------CAXX--XXXXXXXXXAELDREIVHVTL
RDH---RVCFVINEGEDVGKVDPGIFISSII-PGGPAEKAKKIKPGGQILALNHISLEGF
TFDMAVRMIQNSPDNIELIISQSKGICGNTSREGKN-SMASSGVFS--------------
---------------------------------------TDNL---SNRHQGSFLSYTQD
QERNIEELEMTRTQSLLSRLRP-QLSILPL------------------------------
--KG--TGSSCLPSSSEANAGGIYFVELAKEDGTFGFSI--TGGVNTSVLYGGIYIKSIV
PGGPAAKEGQILQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVARLVLERRGPRTAQQCP
V-NNRMGDECMAVSLATALPGRPASCVSVTDGPKFEVKLKKNASGLGFSFVQMERKSCSR
LKNDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLVFQEVLHLLRGASQEVTLLL
CRPPPGVLPEMDQGWQTPELLADKEFTRATCTDSEQSPSLDQEDSWRDSVSPDAGDGLGL
KPE-SFQQATREAQ---WDH-DIERPWA-------TSL--MRPGDSHPHLCRLYQEVD--
------SGASATCLEKDVRQNCYSVCDIRRLERFSY--------SSSLTSLSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--MHVFIVGMSLSSVTLASALQVRGEALSEEEIWSLLFLATEQLLEDLRN-------DSS
DYVVCPWSALLSATGNLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRKLAGLVLGTISEVERRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
ASECRHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPDPHWSTS-----------------THSHCSLLVNRALSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--PSQKGFLQRRSK---VSKRRLKEYALLDGE
VA-----LGRHL---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-STNTFTLFLRI
KFFVSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEISEMHRLSSALWGEDAELEF
LRVTQQFPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAVGGM--LSTSLDNFKVDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSV----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKK-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSRTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--TGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANDSMGDEHMAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSTDKEFTRATCTDSCTSPILDQEDSWRDSASPEAGEGLGL
RPE-SSQKAIRAAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIVRLGSPEL--------DGEDG--EGDMYHPCG
AP----------------SPTSEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTILLPQFCSWG--TVPE-SLPPEES
PESGSEWEDLEEPVDLE--YGCISF----LGS--L---S----FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

TQPSRQNTGMSPTSVTLASVLQVRGEALSEEEIWALLSLAAQRLLEDLRD-------DSS
DYVVCPWSALLSVTGSLSFQDHSSHLEAAPFKAPELLQGQKDGE-QPDASQVHVYSLGMT
LYWSAGFHVPPCQPLQLN-EPLHSVLLTMCEDQPRKRLPLVSVLETCRLHWEEVAVHPAS
AHLHIKRLVGSVLGTISEXXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXX------XX-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-XXXXXXXXXX-----------------XXXXXXXXXXXILPVEVAHDL-----------
------------------------------------------------------------
--------------QEGLRLS---------------------------------------
----------SGSGSPLSVAAENSLPAT--PSQREFLKRKGK---FSRP---EFLLLARE
APVTLHLPGSIV---TKKGKS-------YLALRDLCVVLLSGQCLEVKCDIMSTVGAIFN
AVTTFANLGEITYFGLAYMKRKEFFFLDNDTRLCKVAPEGWSEEPQKKTSWNTFTLFLRI
KFFVSHCQLLQQSQTRHQFYLQLRQDILEENLYCNDETLLQLGVLA-------LQAEFGS
YPVE----EKV-DSRIYFRVEDYIPASLIERMTVLQAQVQVSEMHRLSPVLWGEAAELEF
LRVTQQLPEYGVLVYRVLPEKTRPDG-EMALGICTKGVIVYEMKNDSRIAILRFQWREIG
KISTFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX
YDKCLRMANN-------------------------LNF-TQLAQSKPLNWMQKLSCTD--
-----NALFEC----RLEDTKGGL--HNTSLDNFNVQINKETGA-ERMGG-SPCTGQEQR
--------------QNISLIQKPKPC-DHVSGLPVQSVH---------------------
------------------------------------LGLQKNRGKCFTSQLDQEIVHVTL
SRDPCRGFGFVINEGEETDKVHPGIFISSIF-PGGPAGKSKRIQ PXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXVCGSTPSKEKN-SIANSGVFF--------------
---------------------------------------TDSR---NNGHRGGISSSIQY
QERNSEELELPGTQNMMPRLRP-QLSSLLL------------------------------
--KG---AASCPPSLSETNANEIY FVELAREDGTLGFSV--TGGVNTSVLYGGIYVKSVV
PGGPAAREGQIVQGDRLLQVDGVNLSGLTHKQAVQCLKGSGQVARLVLERRVPRTTQQCP
SANDRLGDECTAVSLATTLPGRPASCVCATDXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXTPVSSADKEFCRKTCPDSGQTPSVDPEDGQGDHDSLGVGKDLAL
SPE-SFRKIPREMQ---SDQ-DIIRPCA-------ASL--MRPQDHHPHLCRRHQEID--
------ALALATSLEKDLRQNCYSVCDIRRLERFSY--------SSSLTRFATDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

QNPVSTAAGMSSSCVTLAEVLWAKGSPLEEEEIWALLYLSTMQLLEDLHK-------DSA
ICVICPWSVLLSPEGNLFFQNNAFQTEAAPFSPPELLHRPSKNQ-HFGLTKMLVYSLGMT
LYWSADYQVPPNQSLQLS-DQLHTLLLTLCEDLPHRRLSPESILEACEAHQKESASLP--
AKFYIKKMVHFAVGSASETEQVVTED------STAFQLNRSHVIRKRLHEKISDTS-TLS
SQMNFHQGKIKEKSIE------ASQR----------------------------------
--------------------------------------------------PE--S-----
------------------------------------------------------------
-----------H------------------RTQVIQAHRS--------------------
--------------------------------------------------VSAVE-----
-EIP------GGTQKNNR------------------------------------------
-------QNLLSLGSTFSVSTKDY--SAAAASQKCLFHRKEK---FSGP---EFIILSSE
PPVTLQLPGSIV---TKKGKS-------YLSQRDLNVILLNGQCLEVQCDIKTKARDVFN
TVVAYANLVEHFYFGLAYLKGKEFFFLDEETKLYKVAPDGWNDQHKKKMSIINFTLFLRI
KFF VNHF NVIQHGLTRHQFYLQLRKDILEERLYCSDETALKLGALA-------LQAELGN
YVSECFPPQM--HGKSYFRVEDYVPASRIEKMTLAYVQRELAKLHRMNRSLFEDEAELEF
LKVTQQLPEYGVLF YRVSQEKKGT EG-DIILGICAKGIIVYENKNHTRIASLRFQWRETE
RISAHRKKFMIESSFSGKKHTFITDTAKTCKYLLDLCSAQHKFNAQMNS RQLRQTSSEDS
K----------FVE-------------------IDKSNSAYAAQREHLALIQRLSRSE--
-----NVLYGA----NLENLSAGM--MSKSCDNLSVETNNRTRDKSNLGR----------
----------------------------SVSGLSQSEMHINLN-GKQRSYDFLSIHSTQN
TVSGEYNNHEKRQYSS--------------------------------IGLEREIIC VSL
KRDSKNGFGFVIIGGENVGKLDLGIFIASII-PGGPADRAGNMKPGGRLISVNNISLEGV
SFNTAVKIIQNCPDEVQLI ISQPK------------------------------------
-------------DMYEEGLNEEKNLSRGNSTSGSEISCVDSGRKKIQDCHTALPK---E
QDTNIDELEKTLSWNLASKLGS-RIPVPSADSLDIE------------------------
-----AADSSHLPSPLETNSKEIYMVE LLKEDGTFGISV--TGGINTSVRHGGIYVKSII
PRGPADKDGQINSGDRLLEVDGISLCGITHKQAVEHLKKSGQIAKLV LERGNYQLAEPCP
TANDRKEDQCAVVSVATSLTDGTKDCCFLTDDNTFE VKLTKNSGGLGFSVLQMEGEACEH
LGGAIVRIKRLFPGQPAEENGEIEVGDVILAVNGKPLKGLLYQDVLHLLRGAPRDVTLLL
CRPPKGVLPEIEQIALTPAPSPVKDLVAEMPGSTEAGNSMDQSTSDGGSTSPDLEDCLDS
PVGEDLSEPPEDDSSAYEEQEAEFEEK-----PIKKLPTSRESFY--KHLWKIHREAS--
-----SSEA-FHSLEEEVKQNCYSPCEFGQTKRFNF--------FSELNRTKIY------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

---------MSSSCATLAEVLWAKGSPLEEEDIWALLYLSTLQLLEDLHK-------DSA
VCVICPWSILLSAEGNLSFQNNASQTEAIPFSAPELLHRQNKNQ-RIGLMKMLVYSLGMT
LYWSADYQVPPNQSLQLS-DQLHSLLLT LCEDLPHKRLSPESILEVCEAHQKESSSLP--
ANIYIKKMVQFVLGSATEVERVATED------STASQLNRSHVIRKRLHEKIPDTS-PLF
SQMNFHQGKLELSTWLNFCATSLLGSRLM--NYSRSTEDYRQLSV-----DYSDTNSISE
IYSETKELKAKMKGIESDLKGLI-------------------------------------
--------------------SFKNRAENLGAHCIIGSLTGDNLRREREYIPGKKKKQ---
-SSLSPLCPKEEEGIMAVLLSLVHVSHLPSSTCLATETSQLISRPQQLRVRKLRETLYSC
HSTYTQ---KCRICSLFIVPRQGHERESVQSKLSACSNCPKSATT-----V------SS-
-TMTLPSFLSGRVTQTHRSWD--PTLSGSRTQSTITQLS---LL----PDSD--------
-T--TSHLN-QVLD---PVNQED-----LCYIKETFFTFLNCPLQFSGP---EFIILSSE
PPVTLQLPGSIV---TKKGKS-------YLSQRDLN VILLNGQCLEVQCDIKSKARDVFN
TVVAYASLVEHSYFGLAYLKGKEFFFLDDETKLYKVA PDGWNDQPKKKTSIINFTLFLRI
KFFVSHF NVIQHSLTRHQFYLQLRKDILEERLYCNDETALKLGALA-------LQAELGN
YASE-----V--HGKSYFRVEDYIPASRIEKMTLAYVQRELAKLHRMNRSLFEDEAELEF
LKVTQQLPEYGVLF YRVSQEKKG TGG-DIILGICAKGIIVYEVKNHTRIASLRFQWRETE
RISAHRKKFMIESSFSGKKHTFITDTAKTCKYLLDLCSAQHKFNAQMNSRQLRQTSSGKQ
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MTSIPFPGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLERRGPRSTQQCP
SANESMGDEHMAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSH
LKNDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRGSASRDAGEGLGL
RPE-SSPKAIREAQ---WGQ-NRERPWA-------SSL--IHSPESHPHLCKLHQERD--
------ASTLATSLEKDVRQNCYSVCDIMKLGRYSF--------SSPLTRLSTDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

------------SSVTLASTLQVKGNALSEEEIWSLLFLATERILEDLNKVKSIFTKCSS
NYVICPWSTLLHTAGSLSFQDNVSFIEAAPFKAPEMLQGQSPNP-QLETSKVHVYSLGTT
LYWSAEFRAPPNQPLQLS-EPLLSILVMMCEDLPQKRVSLPFILEACRVHQKDVVASS--
THFHIKKLVNLVVGSISETVLNSLSK------KERQKGKRKRGERERYREKEDS------
------DGRQTLGNVVDNIEAQVTGRKNLVNSHCPLPLNFLLLPDLKREKEYMEQIVVEE
S-KFVQENR-------SFM---------IRRRLYQKQN------ELSWLST---------
--QKTLEPVNFALFCICAAFPWVSSETGFLSSCTLVSISGLTNETE-----KKKEENGTY
GDMVEPTCDFF----FVKKMSCIHTFKFPIS-CQVSDRD--PRLSAWEFQLNASA--PSN
SKFFHSGLDSIKFYSFSVVLLRI-------------KFNPNVTR-----------KFEAR
YLLLMIRS----------TFSVAPKRSSSVVSS-QRYFLPKNERVMLNQEDSSLSLTNNN
EKIYTFFHAFNDLGLT----ENR-----QNALQSINQRFQIDNLLFSRP---EFIQLSGE
APVTLHLPGSIV-SSTKKGKS-------YLSQRELYVVLLNGQCIEVKCDIKSKARDVFN
LVKTYANLVEHFYFGLASQKGKEFFFLNDETKLYEVAPEGWNDRSKKKTTIVNFTLFLRI
KFF VNHFHL IQHSLTRHQFYLQLRKDILEERIYCNDEMLLQLGALA-------LQVEFGN
YRHE-----V--QGEHYFLAEDYIPASVIERMTASCVELEISKMHRCHGPLSGEEVELEF
LKLTQKLPEYGVFF YQVFQEKKMP EA-EMTLGICAKGIIVYEVKNNSRIASLRFQWREMG
KISTQRKKFTIESSISGKKHTFITDTGKKCKYLLDLCSDQHRFNAQMSSGQLSQ------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

---------MSLASVTLASALQVRGEALSEEEIWSLLSLAAEQLLEDLRN-------GSS
DYVVCPWSVLLSAAGSLSFQDHVSHVEAAPFKAPELLQGSSRDE-KLDVSQVHVYSLGMT
LYWSAGFHVPPNQPLPLS-EPVHTLLLAMCEDQPHRRRPLLSVLEVCRVHQDEVAMYPAP
ASLHIRRLVGLVLSSISEVERRVVEE------STCEPQSRSYLLRKRLHQASS-KSPATQ
ALDDLHPCRVSERS-ME------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLDPHVRCP-----------------SI-INSFMTSPSLASAVPHDV-----------
------------------------------------------------------------
--------------QEDRRLS---------------------------------------
----------SGS--VPLAGAERSRPTT--PSPRSFLQRKGK---FSRP---EFVLMAGE
APVTLHLPGTVV---TKKGKS-------YLALSDLCVVLLSGQCLEVKCDVRSTVGAVFN
AVMSFTNLRETTYFCLAYVKGKEFFFLDNETKLCKIA PEGWSEQPLKT-SLDTFTLFLRI
KFFVSHCGL LQHSLTRHQFYLQLRKDILEERLHCNDEMLLQLGALA-------LQAEFGN
YPKE----EV--ESKAYFRVEDYIPASLLDRMTALRVQVEVSEMHRLSAELWREDAELEF
LRVTQQLPEYG VFIHRVFPEKKRL EG-EMALGICARGVIVYEVKNNSRIATSWFLWRETG
KISTCRKKFTITSSITGKKHTFVTDSAKICKYLLRLCSAQHAFNAQMD SGHTHYLLP--D
QDKFLQMANL-------------------------SPAY--QTQAKALTWIQRLSRSE--
-----NELFAP----RLQDPPRDQ--LNPWLENFNMEISKETGT-ARIRGRWVS------
---------------SFFLSPDQQ-----TFGTLDPSV----------------------
---------------------------------PEAVGPQNNRRETSTADPGQEIIHV AL
NRDPHRGFGFVINEGEDEGQVNPGIFISSII-PGGPAEKTKKIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGICGNITSEEMN-SPANSGILS--------------
---------------------------------------ADIL---SSDQQGSLSLHTED
PNRSRGGLEMA-------------------------------------------------
----RGVGSSCPPSPPETNAGEIYFVE LVKEDGTLGFSV--TGGINTSVLYGGIYVKSIT
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHRQAVQCLRGPGQVAKLV LERRGPRVAQQCS
-ANERMGDERAVVSLVTALPGRPASCVSVTDGPKFE VKLKKNTNGLGFSFVHVERASCGP
FQQDLVRIKRLFPGQPAEKHGAIAAGDIILAVNGRPTEGLVFQEVLHLLRGATPEVTLLL
CRPPPGSLPEMEQGWQTPEVSADKGFAGAVCTDLEQGPIVDQGGHWRDSTSGDTGEGLEL
KPE-AVSKVGREGQ---GNR-DRDRHWM-------KSS--RRPLESHPHLCKLHQGTE--
------TLTLASSLEKDMRQNCYSVCDISRLGSPGW--------DWDD------ACYPSE
LP----------------FHTSGDEEYLIIK-----------------------------
-----------------GASEGQLPCEDCLEADSETIPLPQFCSWG--VLPAESLLLEGS
RESESDWEDLEDAVDAD--AGTLRW----GSH--SLA----------------TKQPKA-
---LSPIVQGDYEEGIDPFDLG---------------TNANQFHPLKG--CLLF------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

---------MSPASVTLASVLQVRGEALAEEDIWALLSLAAEQLLEDLCK-------DSL
DYVVCPWSALLSVAGSVSFQDRVSHLEAAPFKAPELLQERSRDE-QLDVSQVHVYSLGMT
LLWSAGFHVPPKQPLQLS-EPLHSILLSMCEEQPHRRPPLPSVLEACQAHQEAVSVYPAP
AGLHIQRLVGLVLGTISEVERRVVED------SSSVRQSRSYLLRERLHQLSG-ESPAAQ
ALGSLQPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPQSGSS-----------------AHSHGSLSAHSASAGATPHDA-----------
------------------------------------------------------------
--------------QECRRLS---------------------------------------
----------SAS--ALSGAAEISLPAT--PSHKDLLQRNRK---FSRP---EFVLLAAE
APVMLHLPGSVV---TKKGKS-------YLALRDLCVVLLSGQCLQVKCDIESTAGAVFE
AVVSFAHLGELTYFGLAYLKGEEFFFLDSDTRLWEVAPEGWRERPQP--SGDPFTLFLRI
KFF VSHYEL LQHSLTRHQYYLQLRRDILEERLCCDDETLLQLGVLA-------LQAEFGS
YPKE----QG--ESKAYFRAEEYLPASLIERMTALRVQVEVSQMHRLSSAPRGVDAELQF
LRVTQQLPEYGVLV HRVFPEKKRP EG-DTALGVCAKGVVVYAVKPHGRTATLWLPWRETG
KISTCRKKFSITSSVTGKKHTFVTDSVRTCKYLLGLCSAQHGFHALM GSGQSPQVATE--
PSKSMQMACL-------------------------SPAHQHPAQPKPLSWIQRLSCSE--
-----HELFTP----GLLDTTGGV--LSASLDNFNMGTSKDAGP-EGIRG-SLCHGPELP
--------------QDARFIQKPATF-DHLLGLS--------------------------
------------------------------------RGSQNNWRESFAAEAGREVVR VTL
RRDPLRGFGFVIKEGEDMGQANPGIFVSAII-PGGPAEKAKTIKPGGQILALNRIHLQGF
TFNMAVRMIQNSPDTIELI ISQCKDFL---------------------------------
----------------------------------------------SNRHQGRLLSHSRD
QTRNVGELEIAQVQSSMSRLGS-QLSSLPV------------------------------
--KG--AGSSRSPSPSETSAGGIYFVE LVKEDGTLGFSV--TGGVNTSALYGGIYVKSII
PGGPADKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVASLV LERRSARPAQQCP
SANDRTGDGQAAVSLVTAMPGRPASCVSVTDGPKFE VKLKKNTNGLGFSFVQVERDSCSH
SSNDLMRIKRLFPGQPAEEHGAIAVGDIILAVNGRSTEGLVFQEVLHLLRAAPEEVTLLL
CRPPAGALADVEPGWQTPAPSADREFSRAACTDSEQSPSLDREESWRDSASPDTGECLGL
MAE-PLQKALREAQ---GGQ-GRERPWA-------SSL--THAPESQPHLCRLRRDKE--
------APPMPTALERDMRQHCYSVCDLRRLGRFSF--------SSSLTRLASGLF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDTGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSATGSLSFQGHVSHIEAAPFKAPELLQGQSEDK-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRKLAGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
ALECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPDPHWSTS-----------------THSHCSLLVNRALSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--PSQKGFLQRRSK---FSRP---EFILLAGE
APTTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQRLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-STNTFTLFLRI
KFFVSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEISEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLWFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAVGGM--LSTSLDNFKVDGSKEVGA-EGIGR-SPCTGQEQL
--------------KSACVIQKPMTW-DSLSGLPAQSV----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSRTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSTDKEFTRATCTDSCTSPILDQEDSWRDSASPEAGDGLGL
RPE-SSQKDIKAAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--ESDMYHPCG
AP----------------SPTSEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTILLPQFCSWG--TVPE-SLPPEES
PESGSEWEDLEEPVDLE--YGALR-------S--L---S----FRGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

---------MNSASVTLASVLQVRGEALSEDDIWSLLSLGAEQLLEDLCQ-------DAS
DYVVCPWSALLSAAGSVAFQDRVSHIEAAAFKAPELLQEPRHDE-PLDMSQVHVYSLGMT
LYWSAGFQVPPSQPLQLS-ESLHSILLSMCEDQPSRRRPLQSVLEACQVRQEAV----AP
ASLHVQRLVDLVLGTVSEVEHRLVEE------SSSVQQSRSYLLRKRLGQVSG-ESPAIR
APQGLRACGVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPWSGSS-----------------AHSHCSLSANSALAGAMLPDA-----------
------------------------------------------------------------
--------------QECRRPS---------------------------------------
----------SGS--ALSVAAESSLPAT--PAHQDLLPRKGK---VSRP---EFVLLAAE
APVTLHLPGSVV---TRKGKS-------YLALRDVCVVLLSGQCLEVKCDVESTAGAVFQ
AVVSFANLQEITYFGLAYLRGQEFFFLDNETRLCETAPEGWRERPQTA--TGTFTLFLRI
KFFVSHSVLLQHSLTRHQYYLQLRRDILEERLSCDDETLLQLGGLA-------LQAEFGS
YPKE----QV--ESNVYFRVEDYIPASLIGRMTALRAQAEVSRMHRLSSAPLGEEAELQF
LKVAQQLPEYGMLVHRVYPDQKRPGG-EMALGVCPKGIAVYVVKHNSRVATLWVPWREMG
KISTHRKKFSITSSVTGKKHVFAADSAKTCRYLLGLCSAQHAFSALMGSGPLPHDVTE--
PNKSVQKAHW-------------------------SLACQPVAQPTLLPWTQRWACSE--
-----QELFTP----RLRDPAGGL--LSASLDNCHMEASKDAGP-EGIRG-SPCPGWEQL
--------------PEVCLIQRPAMCVDRLPGLPVPSMS---------------------
------------------------------------LASQGDSRKSFAVEPGQEVVYVTL
RRDPLRGFGFVIKEGEDAHHTHPGIFISSII-PGGPAEKAKTIKTGGRILALNHIFLEGF
TFDTAVKMIQNSADTIELII SQSKAVCSSTRGEGKN-RAADSAFFC--------------
---------------------------------------TDFL---NSRHQDSLPSHTQD
QGGNVGELNIAPVQSSIPGLTS-RLSSLPL------------------------------
--KDTGD-SSSSPSALETSVGEIY FVELVKEDGTLGFSV--TGGINTSMRYGGIYVKSIV
PGGPAAKEGQILHGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVVRLVL ERRSPGTAQQCP
SAGDRARDQHPAVSVVTALPGRPTSCVPVTDGPKF EVKLKKNTNGLGFSFVQMERAACSH
LGSDLVRIKRLFPGQPAEEHGAIAVGDVILAVNGRSTEGLIFQXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XXXXXXXXXX---XXX-XXXXXXX-------XXX--XXXXXXXXXXXXXXXXXX--
------XXXXXXXXXXXXXXXXXXXXXXXXXXXRSF--------SSSLSRLTRGLF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDTGMSLSSVTLASALQVRGEALSEEEIWSLLFLATEQLLEDLRN-------DSS
DYVVCPWSALLSATGNLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRKLAGLVLGTISEVERRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
ASECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPDPHWSTS-----------------THSHCSLLVNRALSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--P-QKGFLQRRSK---FSRP---EFILLAGE
APTTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-STNTFTLFLRI
KFFVSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEISEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFDSD
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAVGGM--LSTSLDNFKVDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSV----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSRTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--TGSSCPPSPPEISAGEIYFVEL VKEAGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQKWQTPELSTDKEFTRATCTDSCTSPILDQEDSWRDSASPEAGEGLGL
RPE-SSQKAIRAAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EGDMYHPCG
AP----------------SPTSEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTILLPQFCSWG--TVPE-SLPPEES
PESGSEWEDLEEPVDLE--YGALR------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

--MHVFIVGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSS
DYVVCPWSALLSATGSLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRKLAGLVLGTISEVEKRVVEE------SSSVQQNRSYLLRKRLHGTSS-ESPAAQ
ASECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPDPHWSTS-----------------THSHCSLLVNRAPSGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--PSQKGFLQRRSK---FSRP---EFILLAGE
APTTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQRLEVKCDVESTVGAVFN
AVTSFAKLEELTYFGLAYVKGKEFFFLDSETRLCKIA PEGWREQPQKT-STNTFTLFLRI
KFFVSHYGM LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEISEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKRRP EE-QMALGICAKGVVVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAVGGL--LSTSLDNFNVDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPAQSM----------------------
---------------------------------R--AGSQSNRRKSFTAEPGREIVR VTL
KRDPHRGFGFVINEGEYAGQADPGIFISSII-PGGPAEKAKMIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSRTQD
QDRNIEELDMAGVKSLVPRLRH-QLSFLPL------------------------------
--KG--AGSSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGLSLCGLTHKQAVQCLKGPGQIARL VLERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNANGLGFSFVQMEKESCSH
LKSDLVRIKRLFPGQPAEENGAIEAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSTDKEFTGATYTDSCTSPILDQEDSWRDSASLEAGEGLSV
RPE-SSQKAIRAAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLETSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EGDMYHPCG
AP----------------SPTSEDEEYLAIN-----------------------------
-----------------STCQGQLPCEECLEADSGTILLPQFCSWG--TVPE-SLPPEES
PESGSEWEDLEEPVDLE--YGCISF----LGP--L---S----FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLMKDAGMSLSSVTLASALQVRGEALSEEEIWSLLSLAAEQLLEDLRS-------DSS
DYVICPWSALLSAAGRLSFQGHVSHIEAAPFKAPELLQGQSEDE-QSDASQMHVYSLGMT
LYWSAGFHVPPNQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACGAHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------SSCVQQNRSYLLRKRLCGTSS-ESPVAP
APERLHPCRVSEGS-TE------AQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-HSPEPHWSTS-----------------HSHCSLVVNR-TLPGADPQHQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VYSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFVLLAGE
APVTLNLPGSVV---TKKGKS-------YLALRDLCVVLLNGQRLEVKCDVESTVGAVFN
AVTSFANLEELTYFGLAYMKGKEFFFLDNETRLCKIA PEGWREQPQKT-STNTFVLFLRI
KFFVSHYGL LQHSLTRHQFYLQLWKDVLEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELEF
LRVTQQLPEYGVLV HQVFSEKKRP EE-EMALGICAKGVTVYEVQNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQM GSGPPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFTS----RLRDAAGGL--LSTSLDNFNVDTSKEAGA-EGIGH-SPCTGREQL
--------------KSACVIQKPMPW-DSLSGPLVQNM----------------------
---------------------------------H--AGSQNNRRKSFTAEPGREIVH VTL
KRDPHRGFGFVINEGESSGQADPGIFISSII-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVCGNTPNEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSHTED
QDRNIEDLDMAGVRSLVPRLRH-QLSFLPL------------------------------
--KG--PGSSFPLSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV LERRGPRTTQQCP
SANDSMGDEHMAVSLVTALPGRPSSCVSVTDGPKFE VTLKKNANGLGFSFVHLEKESCRH
LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRPTEGLVFQEVLHLLRGAPQEVTLLL
CRPPPGALPETEQEWQTPELSADKEFTRATCTDSCTSLSLDQEDSWRDSASPDAGESLGL
RPE-SSQKAIREAQ---WVQ-DRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLATSLEKDVRQNCYSVCDIMRLGSPEL--------DGEDG--EGDMCHLHG
AH----------------SPTLEDEEYLTIN-----------------------------
-----------------STCQGQLPCEECLEADSGTIPLPQFCSWG--TIPE-SLPPEEF
QESGSEWEDLEETVDLE--DAALRS----LS------------FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

MQPLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRN-------DSL
DYVVCPWSALLSAAGSLSFQGHVSHIEAAPFKAPELLQGQSEDE-QPDASQMHVYSLGMT
LYWSAGFHVPPHQPLQLR-EPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAP
AGLHIRRLVGLVLGTISEVEKRVVEE------TSSVQQNRSYLLRKRLHGTSS-ESPAAQ
APECLHPCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPEPRWSTS-----------------THSHCSLLVNRTLPGADPQDQ-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SGS--VHSA-ADSSWPTT--PSQRGFLQRRSK---FSRP---EFILLAGE
APMTLHLPGSVV---TKKGKS-------YLALRDLCVVLLNGQHLEVKCDVESTVGAVFN
AVTSFANLEEFTYFGLAYMKGKEFFFLDSETRLCKIA PEGWREQPQKT-SMNTFTLFLRI
KFFVSHYGL LQHSLTRHQFYLQLRKDILEERLYCNEEMLLQLGVLA-------LQAEFGN
YPKE----QV--ESKPYFHVEDYIPVSLIERMTALRVQVEVSEMHRLGSALWGEDAELEF
LKVTQQLPEYGVLV HQVFSEKRRP EE-EMALGICAKGVIVYEVKNNSRIATLRFQWRETG
KISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMG SGQPSHVLFD--
HDKFVQMANL-------------------------SPAH--QAQSKPLIWIQRLSCSE--
-----NELFAS----RLQDAGGGL--LSTSLDNFNVDGSKEAGA-EGIGR-SPCTGREQL
--------------KSACVIQKPMTW-DSLSGPPVQSM----------------------
---------------------------------H--AGSKNNRRKSFTAEPGREIVC VTL
KRDPHRGFGFVINEGEYSGQADPGIFISSVI-PGGPAEKAKTIKPGGQILALNHISLEGF
TFNMAVRMIQNSPDNIELI ISQSKGVGGNNPDEEKN-STANSGVSS--------------
---------------------------------------TDIL---SFGYQGSLLSHTQD
QDRNIEELDMAGVQSLVPRLRH-QLSFLPL------------------------------
--KG--AASSCPPSPPEISAGEIYFVE LVKEDGTLGFSV--TGGINTSVPYGGIYVKSIV
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVHCLKGPGQVARLV LERRGPRTTQQCP
SANDSMGDEHTAVSLVTALPGRPSSCVSVTDGPKFE VKLKKNVNGLGFSFVQMEKESCSQ
LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL
CRPPPGALPEMEQEWQTPELSADKEFTRATRTDSCTSPILDQEDNWRDSASPDAGEGLGL
RPE-SSQKAIREAQ---WGQ-NRERPWA-------SSL--THSPESHPHLCKLHQERD--
------ASTLATSLEKDMRQNCYSVCDIMRLGSPEL--------DGEDG--EGDMYHPCG
AP----------------SPTSEDEEYLTVN-----------------------------
-----------------STCQGQLPCEECLEADSGTIPLPQFCSWG--TVPE-SLPPEES
PESGSEWEDLEEPVALE--YGALRS----LS------------FGGL---NV--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

---------MSVASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRN-------DSS
DYVVCPWSLLLSAAGGLSFQDHVSHIEAAPFKAPELLQGSNEEG-QPDVSQMHVYSLGMT
LYWSAGFRVPPNQPLQLQ-EPVHSLLLAMCEDQPRRRRPLQAVLEACRIHQEEVAVYPAP
ASLHISRLVGLVLGTISEVERRVVEE------NACEQQNRSCFLRSRLHQVDG-ERPGAP
ASDALQPRRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLDRCWSTT-----------------AHSGNS-FVNSTFAGASPCDC-----------
------------------------------------------------------------
--------------EESPWYG---------------------------------------
----------SEP--MLLAEAESSQPAT--SSPRNFLQRKGK---FSRP---EFILLAGE
APVTLHLPGSIV---TKKGKS-------YLALRDLCVVLLNGRCLEVKCDMESTAGAVFN
AVMSFANLGETTYFGLAYVEGEEFFFLDKDTRLCKVA PEGWREQHPKG-SVDTFTLFLRI
RFFVSHYRL LRHSLTRHQFYLQLRKDILEERLYCNDETLLQLGVLA-------LQAEFGS
YPKE----QV--EGKAYFRIQDYIPARLIERMTAIRVQVEVSEMHRLSSAPWGEDAELEF
LEIAQQLPEYGVLV HRVSPEKKRP EG-KMALGVCTKGIIVYEVRGSRRIATSQFPWRETG
MISTHRKKLTITSSTTGKKYTFVTDSSKTCKYLLGLCSSQHWFNAQT GSKHPSHRFTG--
QDKFAQIASL-------------------------SSAH--QTWANPITWIQKLSCSE--
-----NELCVP----RLQDATGGQ--LGTSMESKQ--GFKEPGK-ERIGS-SPYTGGEQL
--------------HSIGLNQKPAQT---VFGTAGHSMCAGSNCLGRRN-----------
---------------QI-------------CCFDSVSGSQNSKRKDLFGEPNQDIMCV ML
KRDPVHGFGFVINEGEDAEQTRPGIFISSLI-PGGPAERAKKIKPGGKILALNHISLEGF
TFSMAVRMIQNSPDDMELI ISQPKGVCGTIHSEEKN-STASSGMFC--------------
---------------------------------------TDIL---SKRCQGRQSPHIHD
QNGSVTGPEMAQ------------------------------------------------
------GADSCPPSPLQTNTGEIYFVE LVKEDGTLGFSV--TGGINTSVPHGGIYVKSII
PGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV LERRGPRAAPQYP
SADDRMGDVHMAVSLVTARPGRPASSVSVTDGPKFE VKLKKNSRGLGFSFVQMERGNCIH
TKSDLVRIKRLFPGQPAEEHGAIAAGDIILAVNGKPIEGLAFQEVLHLLRGAPEEVTLLL
CRPPPGILPEMEPGWQTPELSGYQRLTMATCAGSEQSPSLNQEDNWRDSMSLDAGEGLSP
RPE-SSYKDVRQVK---GDR-EKERPWA-------KSW--MHPMESHPHVCKLHPEPE--
------TPALATSLEKDMRQNCYSVCDIRRLGRFSF--------SSSLTRLATDIF----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

LCHMCVFAGMSPASVTLASALQVRGEALSEEDIWSLLSLATERLLEDLCD-------DSS
NYVVCPWSVLLSATGSLSFQDHVSHIEAAPFKAPELLQGQSNDE-QLGASQMHVYSLGMT
LYWSAGFHVPSNQPLQLC-QPLHSILLTMCEDQPGRRLPLQSVLEACQIHWEEAAVHPTS
ANLHVRQLVGLVLGTISEVERRAVEE------SSSGQRDRSHLLRNRLHQASC-ESQAAW
ALGCAHRCRVSERS-TE------TQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-SSLEPGLNTS-----------------ARGRCSLAVNSALPVQVPPDL-----------
------------------------------------------------------------
--------------QEGRRLS---------------------------------------
----------SAS--ALP---ENSQPAT--PSQRGFLQRKGK---FSRP---EFVLMAGE
APVTLYLPGSIV---TKRAKS-------YLALRDLCVVLLSGQCLEVKCDITSTVGAVFS
AIASFASLGELTYFGLAYMKGKEFFFLDAETRLCKIAPEGWSEQPQKKSSPNAFVLFLRI
KFF VSHYGL LQHSWTRHQFYLQLRKDILEEKLYCSDETLLQLGVLA-------LQAEFGS
YPEE----QV--ENKAYFRVEDYIPASLIERMTALRAQVEVSEMHRLSPMLWGEDAELEF
LRVAQQLPEYGVLV YQVLPEKTRLEG -EMALGICAKGVIVYEVRNNSRIATLRFQWREIE
KILAYRKKFIITSSVTGKKHTFVADSVKTCKYLLGLCCAQHGFNAQMS SPGVTSGIIISD
SDKCVQMASL-------------------------SLAH--LAQSNQLTWIQRLSSSE--
-----NALFIP----GLEDAAGGL--LRRSLDNFTMDTSKGTRA-QGLRG-SPCLGREQL
--------------ERLCLIQKPTTC-DLLSRQPAQSM----------------------
---------------------------------RTDLGSRNNRRRSFIAEPDGEIVH VTL
SRDPHRGFGFVINEGEDVGKVDPGIFISSII-PGGPAEKAKKIKPGGQILALNRISLEGF
TFDMAVRMIQNSPDNIELI ISQSKGVCGNTSSEEKN-STANSGVCS--------------
---------------------------------------TDSL---SNGHQGSLSSHTQD
RERNIEELEMAQTQSVMPGLSP-QLSALPL------------------------------
--KG--AGSSCPPSPSETNASEIYFVE LVKEDGTLGFSV--TGGINTSVFCGGIYVKSIV
PGGPAAKEGRILQGDRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLV LERRGPRIAQHCP
SANDRMGEECTAVSLATVLPGRPASSVSATDGPKFE VKLKKNASGLGFSFVQMESEHRGH
LKSDLVMIKRLFPGQPAEENGAMAVGDLILAVNGRSTEGLDFQEVLHLLRGASQEVTLLL
CRPPPGALPEMDQGWQTPVLAADKEFSRAACTDLEQSPSLDQGDSRRDSASPDTGEGLGL
RPE-SFQQATQEAQ---WDQ-DTERPWA-------TSL--TDPRDSFPHLCRLHQEME--
------ASTLATSLEKDLRQNCDSVCDIRRLGRFSY--------SSSLTRLSTD------
-------------------------IF---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

Query Results

"ENSGT00920000148995_2"

ENSGT00920000148995_2