Query Results 

MGLANRRHGLGTCSPISTRGGENCKTGKIKCLLKETHSW---------LRREVGNRLNGI
HPWELDACVAVLPHQGFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPAGASPDKLPGSLGHPRPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEIAQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCMEKMQKDSSAGKEP----VLPALPHKPC-VPVVTRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEVLGHKTTGSPS
DEEPEVLQVLEGSPQDEKIQVGPWTDNH-HLKKESSGVVLALSAECPATAASELYTDRLD
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGPQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGELASGGSRVDLGLQ
IDHTGHDMLPNM---RDGDTSQDLGPKD---------PPDH-NR-LAVKEFEHLPG-ETE
EKSLLLGS-DNEDEKLSKGQHCIEIS---LPGDLVTAERDQLA-TTEPQDVS--KNFSVV
PNQDKTHEIMKLLAVGTSEISP-QAIDPHAEGQIGQMAAMQKNKLFK-DDGIQSESLPGQ
QGDLSAFLHQEGKREKVVPRNGELYHCVSENEHGPPTRKDMLRSSFVTRHSRIPVLAQEI
DSTFESSSAVSAKEKLLQKKAYQPEIVKLLVEKRQFKSFLGDLSSASDKLIEEKLAAAPV
PFSEEEVFAPFSRLAADSHLSRSVEDSFLSPIISQARKSKIPRPVSWVSTDQINGSASPQ
FLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRTGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGPKGSGSLHHHSTSSKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGDQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 340)

WKVLRKIGGG
GFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPQEFNVFLDHISNLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LMSVFDNSMKTFG
VIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENVIPVGVSPEKLPGSPGHQRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGPGNGMLNAPSLGSPIRVRSETTQLDRDVPLVRKLRSIHSFELEKRMTLESKPDTD
KFLETCLEKKQKDLKV-AETPVAAVPPLSQKTSVPAPLTARTDHVWHYDEEYLPDASKPV
SANSPDHADGVMSNGFVAVNLSSCRQEVDSKEWVIIDKERDLQDFRTNEALGHKMTGSPS
DEEPEVLQVLEEPLPEEQSREGSWAGNNVHAKNQTSGVEFVLDMECH-PAASEQLTDKLE
LLSGAAGQLLAATPTSPMEAQAEGALT---------------------------------
--------------------------------------------------PITIPRPSVA
STQSASESFHYGHQLERREQDGQSVEHTVELSSPKESLPGLVGTEDGLPACASRPDLVLN
INQE---VLDRGGLVKESLSLLDCDQK---------DLPE-HNGIQEEKEFGTIPV-EEA
EEEGLPVVSEDAIEMLSKEQ------NSSLPGNSKSAEEEPLT-NTEAAQESKSKPVCLV
PNQDD---VLKSIAPKTSELSPSRHNNTHVNRQANKTATIQENGFHSDKEEVHSQDLKCH
QVALTTILQQENKKEKNAPRNGELFHCISENENSYRSKKDSVKSSFVFRQSRIPVLAQEI
DSMSDS-SSVSAKEKLLLKKAHQTDLVKLLMEKRQLKSFLGDLSSASDKSLDEKMAAAPV
PFSEDDVLASFSRFTLDSHFSKQNEDSSLSPSSPQSRKSKIPRPVSWATTDQVTSSSSAQ
FFPRPPPGKPPIRPGVEARLRRYRVLGSSNSDSDLISRLAQILQNGS--QRPRSSTQCKS
PGSPHSPKTPPKSPVIPRRSPSASPRSSSLPRTASSSPSRAGRSH-HDQRSSSPHFGRSK
SPPSHSGSSSSRRSCQQEHCCNKTSKNGLKGSGSSFHHSPNSKTSTGK----SKSTTKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------WK

PF07714 // ENSGT00920000148982_1_Domain_0 (113, 349)

VLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSMFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGADGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGQPNGILNAPSIGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLEICLEKMQKDSSAGKES----ILPALLHKPC-VPAVSRTDHIWHFDEEYLPDASKPA
SANTAEQADGVGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGCKTTGSPS
DEEPEVLQVLEESPQDEKLRLGPWAENN-HLKKETSGVILALSGECPATAASEQYTDRLE
LQAGAASQFIAVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPVEPTVELYSPRENFSGLVVTEGEPPSGGSRTDFGLQ
IDHIGHDMLPNV---RECDRSQDLGPKD---------IPDH-NR-LAVRECESLPV-ETE
GKSTLLGS-ENEDAKLSKGQHYMEISS--LPGDLVPMERDHSA-PTEPFDVTKTQTFSVV
PNQDKNHEIMKLLAVRTSEISP-RVIDPHVEGHIGQVAAMQKSKLSK-DDDIKSEDFPGH
QGDLSTFLHQEGKREKIVHRNGELFPCVSESEPCPPSRKDVVRSSFVTRHSRIPVLAQEI
DLTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKLLEERLATVPP
PFSEEEVFTPFSRLAVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVSSSTSSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNSLKGSGSLHHHSASTKAPPGK----SKSASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 270)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIK------
-----------------------------PPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGVPAAGSPDKLPRSLGHTRPQE-RDVWEEM-DINKNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEIMQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETWY-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
-------------------------------MGPANRRCGLATRSPISTCGGE

PF00069 // ENSGT00920000148982_1_Domain_0 (114, 332)

LRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRTVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSLFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFENSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLEACLEKMQKDS---KES----VLPALLHKPC-VPVISRTDHVWHYDEEYLPDASKPA
SANTPEHADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLQMGPWAENN-HLKKETSGVVLAFSAECPATAVSEQYTDRLE
LPVGAASQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPMEPSVELYSPRENFSGLVVTEGELPSGGSRTDLGLQ
IDHIGQDMLP---DIRESDKSQDLGPKD---------LPD--YNRLVVREFENLPG-ETE
EKSILLGS-DNEDEKLSKGQQCIDI-S--LPGDLVTVERDHSA-TTEPLDVTKTQTFSVV
PNHDKNHEIMKLLAIGTSEISSRVIDPHVEGQ-IGL---------SK-NDHIKSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGPQTRKDMVRSSFVTRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLAAVPV
HFSEEEVFTPFSKLAVDSHLSRSAEDSFLSPIISQSRKSKIPRPVAWVNTDQVNSSTSSQ
FLPRPPPGKPPTRPGVEARLRRYRVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKT
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGPKGSGSLYHHTASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 333)

WKVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDSSGGKES----ILPAVLHKPC-VPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGASNGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLLLGPWAESD-HLKKETSGVVLVLSGECPATAASEQYTDRLE
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDLLPNI---RECNKSQELGPKD---------LPDH-NR-LAMREFESLPR-ETE
EKSNLLGL-DNEDEKLSKGQHYIEIAS--LPGDLVTVERDHSA-TTEPLDVTKTQTFSVV
PNQDKNQEIMKLLAVGTSEISP-QVIDPHVEGQIGQVAAMQKSKISK-DDDIRSEDLPGQ
QGDLSTFLHQEGKREKMAPRNGELFHCVSESEHCPPSRKDMIRSSFVTRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVRLLVEKRQLKSFLGDLSSASDKLLEERLAAVPA
PFSEEEVFAPFSRLAVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVSTDQVSSATSTQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSSSLHHHSASTKAPPGK----SKSATKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_2 (111, 951)

WKVLRKIGGG
GFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKL-QGKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LVSVFDNSMKTFG
VLESDPFDWEKSGSDGSLITTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQFSDGENGIPVIVSPEKLPGSPNHQRLQE-KDVWEEM-DANRNK-IKMGICKAATED
ENSNGQGNG--HAPSLGSPIRVRSETA-QDRDVPLLRKLRTIHSFELERRMTLESKPDAD
KFLDNCPEKPQRETNTGGPLAEGSCASPRQSKKT-VPPTAQADHAWHYDDEYIPEGSKPG
SASSPEHLDGAGSNGFVAVNLSSCRQEVDSKEWVIVDKDRDLKDFGTNQ--GQKLTGSPS
EEEPEVLQVLDDSPQEYNAKLSPWTDNN-THNKLDPAVRLEVV------TSTGPFTDRLD
PMSATAGQLLAATPTSLMEAQAEGALT---------------------------------
--------------------------------------------------PMTMPRPSAT
PTQSASESFPYGPNLEKRDRDLQD------MLSPQDNLTLYRSLED----GVTCANMALH
LDKTSQEK--------TCVKNQIKGQTNE---CDN--LLG--NKHCVETPVKSYSS-PL-
-LNHLNAN-KEQSDKVARPQECASLEQSRPLGDVYPAT-------V------APRTSGSV
PNEASLIDVQKPEAAQTVIISSKQADDYMELCIVSPLKDIQQNGFHNVKDIVVTNGFLDH
KMNVPVLLNEEGNEDQ---KNGEQLHIS-------DMSQQLKKDYAKSRHSRIPVLAQEI
DTASDSSSAISAKEKLFLKKAHQTDLARLLMEKRQIKSFFGDLSSASDKSLEEKSSPPAV
QLSDDDNF-SYPKVITDSNVVKLSEDGTITSHSPPSRKSKIPRPVSWTSNDQITSSPTTQ
FLPRPPPGKPPTRPGVEARIRRYKVLGSGNSDSDLLSRLAQILQNGSRSQKSRSSSQCKS
PGSPHSPKTPPKSPVIPRRSPSASPRSSSLPRTNSSSSSRAGRTHYHDPRSSSPHVGRSK
SPPSLSGSSSSRRSCQDHCCNK-QSKNISKGPGSGHHLTSSKTSRAKSSSRESKVSNKLS
R

------------------------------------------------------------
-------------------------------MESLSKDWGWG-------LWRNLRCLGHA
HQGKCCTEGGI------------SSTTKTSSENGSCC-------FEKAA

PF00069 // ENSGT00920000148982_1_Domain_0 (170, 332)

RFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 391)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYKVSTSGPQAFNSLS

PF16208 // ENSGT00920000148982_1_Domain_1 (391, 486)

YTSGP-GACISSSSFS-------RMGSSSF
RGGLGAGYGG---A-SGGITTVT-VNQSLLSPL-------------------NLEVDPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VRT

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 678)

QEEKQIKTLNNKFFSFIDKVRFLEQQNKMLETKWSLVQQ--QKMARSNMDNM
FESYINNLKWQLET-------LGQEKLKLEAELGN-----------------MHGLVEDF
RNKYEVEISKCTEMENEFVLIKEYVDEAYMNKMELESSLK----GLTAKISFLRQLY---
-EEEIG----------S

ENSGT00920000148982_1_Linker_2_3 (678, 732)

CSPKSRI--HLWCCSWTTA---------AS-WTWTASSLRSRP
EGFPG---GCH

PF00038 // ENSGT00920000148982_1_Domain_3 (732, 839)

ADTEQHGELAIKDANAKLSELEAALQLASQDMARQLRE-----------
-------------YQELMN-----------------VKLALDIKIATY--RKLLEGEESW
LESGMQNMSIHMKTTSSYAG-GQSLAYGG---------LTSPGLSYGLGSSFGSGMGSSS
FSHTSSSRAVVVKKIETRDGKLVSESSDVL--LRITATVSPCSDGKLLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-NLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQQ-PEK-KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDMLP---NIRESNKSQDLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKDHSA-TTEPLDVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISSRDIDPHVEGQ-IGQVAEMQKNKISK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
PFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKTPQGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKHLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVCKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPREN-SGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLPNI---RESNKSQDLGPKE---------LPDR-NR-LVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKDHSA-TTEPLNVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISP-RDIDPHVEGQIGQVAEIQKNKVSK-DDDIMSEDLPSH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 334)

WKVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLEHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKAFG
VIESDPFDWEKTGTDGSLTTTTASATPQLHTRLTPAAIG-IANATPIPGDMLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DTNRNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLALEPKPDTD
KFLETCLEKMQKDPSAGKES----TLPALLHKPC-VPAVSRADHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEALGPKTTGSPS
DEEPEVLQVLEESPQDDKFQLGPWAEND-RLKKETSGVVFVLSGECPATAASEQYIDRLE
LQAGAASQFITATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDPHTIEPTVELYSPRENFSGLVVIEGEPPSGGSRTDLGLQ
IDHIGHDMLP---NIREYDRSQDLGPKD---------LPD--HNRLAMREFEDLPR-ELE
EKSIVVGS-DNEEEKLSKRQHYIEISP--LPGDLVTMERDHSA-TTEPLDVTKTQTFSVV
PNQDRNQEIMTLLAVQPSEVSPRVIDPYVEEQ-IGQVAAMQKSKISK-EDDIKGEDLPNH
SGDLSTFLHQEGKREKIAPRNGELFNPVSESEHCPPSRKDVVRSSFVTRHSRIPVLAQEI
DSTFDSSSPVSAKEKLLQKKACQPDLVKLLVEKRQLRSLLGDLSSASDKLLEERLTAVPA
PFSEEEVFTPFSRLAADSHLSRSAEDSFLAPIISQSRKSKIPRPVSWVNTDQVNSSAPSQ
FLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGTPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSFHHHSASAKAPPGK----SKSASKLS
R

MGLANRRHGLGTCSPISTRGGENFKTGKIKCLLKETHFW---------LRREVGTRLNGN
HPWELDACVAVLPHQYFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESEPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLAHARPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGHVNGILNAPSLGSPVRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCMEKMQKDSSAGKE----SVLPALPHKPC-VPVVSRTDHIWHYDEEYLPEASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLKDFRTNEVLGHKTTGSPS
DEEPEVLQVLEGSPQDEKMQVGPWTDNH-HLK-ESSGVVLALSAECPATAASEQYTDRLD
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGPQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGELPSGGSRMDLGLQ
IDHIGHDMLPNM---RDGDISQDLGPKD---------LPDH-NR-LVVKEFENLPG-ETE
EKSI-LGS-DNEDEKLSKGQHCVEIS---LPGDLVTTERDQSA-TTEPLDGLKTQNFSVV
PNEDKNHEIMKLLAVGTSEIS--QVIDPHAEGQIGQVAVMQKTKLFK-GTDIKSEDLPGH
QGDLSTFLHQEGKRDKIVPRNGELYHCVPESEHCPPTRKDMLRSSFVTRHSRIPVLAQEI
DSTFESSSAVSAKEKLLQKKAYQPELVKLLVEKRQFKSFLGELSSASDKLIEEKLAAAPV
PFSEEEVFTPFSRLAVDSHLSRSAEDGFLSPIISQSRKSKIPRPVSWVSTDQVNSSASLQ
FLPRPPPGKPPIRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTPQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGPKGSGSLHHHSASSKTPPGK----SKPASKLS
R

------------------------------------------------------------
-----------------------------------EKDWGWG-------LWRNLRCLGHA
HQGECCTEGGI------------SSTTKTSSENGGCC-------FEKAAR

PF00069 // ENSGT00920000148982_1_Domain_0 (171, 332)

FIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 388)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYKVSTSGPQAFS

PF16208 // ENSGT00920000148982_1_Domain_1 (388, 486)

SLSYTSGP-GACISSSSFS-------RVGSSSF
WSGLGGGCGRASG--MGGITTVT-VNQSLLSPL-------------------NLEMNPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VYS

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 677)

QEKEQIKSL-NKFASFIDKVRFLEQQNKMLETKWSLLQQ--QNMARSNMNDM
FESYINNLRRQLET-------LGREKLKLEAELGN-----------------MQGLVEDF
KNKYEDEINKRTELENEFVLIEKAVDEAYMNKEGLTD--K----I-----SFLRQLC---
-EEEIG----------

ENSGT00920000148982_1_Linker_2_3 (677, 739)

SCSPRSWT--RLWCCPFTTA---------AS-WTWAASSRRS--
RHS---------TRRFVG

PF00038 // ENSGT00920000148982_1_Domain_3 (739, 840)

ELAVKNANAKLSELEAALQRAKQDMAQQLLV-----------
-------------YQELMN-----------------VKLALDVEIATY--RKLPEGEESR
LESGMQNMSIHMKITSSYVG-GQSLAYGG---------LTTPGLSYSLGSSFVCGGAPAP
S----------ATSNETRDGKLVSESSNVLPNLRITATVSPCSDGKLLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTTAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPMEPTVELYSPRENFSGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLP---NIRESDKSQDLGPKE---------LPD--RNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCMEISS--LPGDLVIVEKDHSA-TTEPLHVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISPRDIDPHVEGQ-IGQVAEIQKNKVSK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQARGTFTTSTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGADGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDRLPGSPGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPVRVRSEITQPDRDAPLVRKLRSIHSFELEKRLTLEPKPDTE
KFLETCLEKMHKDSSTGKGS----AVPALLQKPC-LPAASRTDHIWHYDEEYLPDASKHA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDERLQLGSWAGNS-HLRKEPSGVVLALSAECPAAAPSEQYTDRLE
LQAGATSQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQHLEK--KDLQPVEPTVELYSPRENFSGLAGTEGE----------GLQ
ADPVGQDPLPQV---RESDRHQELGPKD---------LPHD-NG-LVVREFGGFSV-EIQ
EKSMLLGS-DNEDEKLSKEQYCVELSL--R-ADLGTEEKD-PSAATEPLDVTKTQPSSVV
PSQGRNSELMQLLAAGTSDFSP-RVIDPHVEGQLGQVAATQKSRLSQ-DDAVQMEGLPEH
PGGLSALLCQEDKGEKSAPRNGERIHRVSENERAPPARKDAGRSALVTRHSRIPVLAQEI
ESVFEASSPVSAKEKLLQKKAYQPDLVRLLVEKRQFRSFLGDLSSASNKLLEEKLAAVPV
PFSEEDVFMPFSRLAVDPPLSRSAEDSFLSPVISQSRKSKIPRPVSWVSTDQVGSSPSSQ
FLPRPPPGKPPARPGVEARLRRYRVLGSSNSDSDLFSRLAQILQNGS--QKPRSITQCKS
PGSPHSPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HEQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSRSGPKGSGSLHHHPASSKAPPGK----SKPANKLS
R

------------------------------------------------------------
-------------------------------MESLSKDWGWG-------LWRNLRCLGHA
HQGECCTEGGI------------SSTTKTSSENGGCC-------FEKAAR

PF00069 // ENSGT00920000148982_1_Domain_0 (171, 332)

FIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 415)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYRVSTSGPQAFSSLSYMSGP-DACINSSSFS-------Q

PF16208 // ENSGT00920000148982_1_Domain_1 (415, 486)

VGSSSF
WSGLGGGCGRASG--MGGITAVT-VSQSLLSPL-------------------NLEMNPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VYS

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 637)

QEKEQIKSL-NKFASFVDKVRFLEQQNKMLETKWSLLQQ--QKMARSNMNDM
FESYINNLRRQLET-------LGQEKLKLEAELGN-----------------MQGLVEDF
KNKYEDEINKRTEMENEFVLIEKAVDEAYMNKVELE

ENSGT00920000148982_1_Linker_2_3 (637, 737)

SPRK----D-----QLPRQLC---
-EEEIG----------SCSPRSWT--RLWCS--------------AS-WTWTASSRRS--
RRWLGSMGMTCMGSRL

PF00038 // ENSGT00920000148982_1_Domain_3 (737, 840)

RLRLAVKNANAKLSELEATLQRAKQDMAQQLLV-----------
-------------YQELMN-----------------VKLALDIEIATY--RKLPEGEESR
LESGMQNMSIHMKITSSYVG-GQSLAYGG---------LTSPGLSYSLGSSFVCGVGSSS
FSHISSFRVV-VVKNETRDGKLVSESSNVLPHLRITATVSPCSDGKLLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPMEPTVELYSPRENFSGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLP---NIRESNKSQDLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCMEISS--LPGDLVIVEKDHSA-TTEPLHVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISPRDIDPHVEGQ-IGQVAEIQKNKVSK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKTPPGK----TKPASKLS
R

MGLANRRHRLGTCSPISTRGGENCKTGKIKCLLKETHSW---------LRREIGNRLNGI
HPWELDACVAVLPHQGFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCMEKMQKDSSAGKEP----VPPALPHKPC-VPVVTHTDHIWHYDDEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEVLGHKTTGSPS
DEEPEVLQVLEGSPQDEKIQVGPWTDNH-HLKKESSGVVLALSAECPATAASELYTDRLD
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGPQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGELASGGSRVDLGLQ
IDHTGHDMLPNM---RDGDTSQDLGPKD---------PPDH-NR-LAVKEFEHLPG-ETE
ERSLLLGS-ENEDERLSKGQHCIEVS---SPGELVTAERAQLA-ATEPLHVSETQNCSVL
PNQDKTHEIMKLLAVGTSEISP-QAIDPHAEGQIGQMAAMQKNKLFK-DDGIQSESLPRQ
QGDLSAFLHQEGKREKVVPRNGELYHCVSENEHGPPTRKDMLRSSFVTRHSRIPVLAQEI
DSTFESSSAISAKEKLLQKKAYQPEIVKLLVEKRQFKSFLGDLSSASDKLIEEKLAAVPV
PFSEEEVFAPFSRLAADSHLSRSVEDSFLSPIISQARKSKIPRPVSWVSTDQINGSASPQ
FLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGPKGSGSLHHHSTSSKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 270)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIK------
-----------------------------PPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSVFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPGPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGHANGVLNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETWY-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
-------------------------------MESLSKDWGWG-------LWRNLRCLGHA
HQGECCTEGGI------------SSTTKTSSENGGCC-------FEKAAR

PF00069 // ENSGT00920000148982_1_Domain_0 (171, 332)

FIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 401)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYKVSTSGPQAFSSLSYTSRP-GACI

PF16208 // ENSGT00920000148982_1_Domain_1 (401, 486)

NSSSFS-------RVGSSSF
WSGLGGGCGRASG--MGGITTVT-VNQSLLSPL-------------------NLEMNPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VYS

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 677)

QEKEQIKSL-NKFASFIDKVRFLEQQNKMLETKWSLLQQ--QNMARSNMNDM
FESYINNLRRQLET-------LGQEKLKLEAELGN-----------------MQGLVEDF
KNKYEDEINKRTELENEFVLIEKAVDEAYMNKEGLTD--K----I-----SFLRQLC---
-EEEIG----------

ENSGT00920000148982_1_Linker_2_3 (677, 736)

SCSPRSWT--RLWCCPFTTA---------AS-WTWAASSRRS--
RPEDF-----PGGRH

PF00038 // ENSGT00920000148982_1_Domain_3 (736, 840)

HRCRLAVKNANAKLSELEAALQRAKQDMAQQLLV-----------
-------------YQELMN-----------------VKLALDVEIATY--RKLPEGEESR
LESGMQNMSIHMKITSSYVG-GQSLAYGG---------LTSPGLSYSLGSSFNET-----
-------------------------------------------LVALLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPVRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEAPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPMEPTVELYSPRENFSGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLP---NIRESNKSQDLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCMEISS--LPGDLVIVEKDHSA-TTEPLHVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISPRDIDPHVEGQ-IGQVAEIQKNKVSK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQLDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQQPEK--KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDMLPNI---RESNKSQDLGPKE---------LPDH-NR-LVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKDHSA-TTEPLDVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISS-RDIDPHVEGQIGQVAEMQKNKISK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
PFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPQGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTINTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHRRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPREN-SGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLPNI---RESNKSQDLGPKE---------LPDR-NR-LVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKDHSA-TTEPLNVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISP-RDIDPHVEGQIGQVAETQKNKVSK-DDDVMSEDLPGH
QGDFSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTQKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSLLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PASPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
-------------------------------MESLSKDWGWG-------LWRNLRCLGHA
HQGKCCTEGGI------------SSTTKTSSENGSCC-------FEKAA

PF00069 // ENSGT00920000148982_1_Domain_0 (170, 332)

RFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 391)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYKVSTSGPQAFNSLS

PF16208 // ENSGT00920000148982_1_Domain_1 (391, 486)

YTSGP-GACISSSSFS-------RMGSSSF
RGGLGAGYGG---A-SGGITTVT-VNQSLLSPL-------------------NLEVDPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VRT

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 678)

QEEKQIKTLNNKFFSFIDKVRFLEQQNKMLETKWSLVQQ--QKMARSNMDNM
FESYINNLKWQLET-------LGQEKLKLEAELGN-----------------MHGLVEDF
RNKYEVEISKCTEMENEFVLIKEYADEAYMNKMELESSLK----GLTAKISFLRQLY---
-EEEIG----------S

ENSGT00920000148982_1_Linker_2_3 (678, 732)

CSPKSRI--HLWCCSWTTA---------AS-WTWTASSLRSRP
EGFPG---GCH

PF00038 // ENSGT00920000148982_1_Domain_3 (732, 839)

ADTEQHGELAIKDANAKLSELEAALQLASQDMARQLRE-----------
-------------YQELMN-----------------VKLALDIKIATY--RKLLEGEESW
LESGMQNMSIHMKTTSSYAG-GQSLAYGG---------LTGPGLSYGLGSSFGSGMGSSS
FSHTSSSRAVVVKKIETRDGKLVSESSDVL--LRITATVSPCSDGKLLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-NLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQQ-PEK-KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDMLP---NIRESNKSQDLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKDHSA-TTEPLDVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISSRDIDPHVEGQ-IGQVAEMQKNKISK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
PFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSR
SPPSHSGSSSSRRSCRQEHCKP-S-KNGLKGSGSLHHHSASTKTPQGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDKSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGQPRPQE-KDVWEEM-DANKNK-IKLGICKAATEA
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKCLTLEPKPDTD
KFLETCLEKMQKDTSAGKE----SILPALLHKPC-VPAMSRTDHIWHYDEEYLPDASKPA
SANTPEQGDGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEVVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDMLPNF---RESNQSQDLGPKE---------LPDH-KR-LVVGEFENLPG-ENE
EKSILLES-DNEDEKLSRGQHCVELSC--LPDLL-MVEKDHSA-TTEPLDVTKTQTFSVV
PNQDKNKEVMKLLTVGTSEISP-RDIDPHAEGQIGHVAEMQKSKISK-DDDIMNEDLPGH
QGDFSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSFPVSAKEKLLQKKSYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
SFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSANTKTPPGK----SKPANKLS
R

---------------------------------MELANWNFALWTHC-PISARGGELNGN
YPWKLNVFVAVRPHQCFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTVSTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRP----------------------EMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFNIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLATTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGMSPDKLPGSLGHPHPQE-KDVWEEM-DVNKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKHLTLEPKPDTD
KFLETCLEKMQKDSSTGKES----VLPTLLHKPC-VPAGSRTDHIWHYDEEYIPDASKPA
SANTPEQAGGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEESPQDGKLQVGPWTNND-QLK-EASGAVLVLCGECPATPVSEQYADRLD
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFQYGQQPEK--KDLQLMEPTVDLYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDILPNI---RDSDKSQDLGPKE---------LPDHN--RLVMKEFDNLPG-ETE
EKSRLLGS-DNEEEKLSKGQHCVELS---LPGDLVTTERDHSA-TMELLDVSNIQNFSVV
PNQDKNHEIMKLLSVGTSEISP-RIIDPYVEGQIGQVVAVQKSKLFK-DDEIKSEDLPGH
QGDLSTFLHQEGKREKIVPRNGELYHCVSENEHGPQTRKDVVRSSIVNRHSRIPVLAQEI
DSTFESS-AVSAKEKLLQKKACQPELVKLLVEKRQFKSFLGDLSSASDKLIEEKLAAVPV
SFSEEETFTPFSRLAVESHLNRSTEDSFLSPIISQSRKSKIPRPVSWVNTDQVMSAASCQ
FLPRPPPGKPPARPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRNTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNSPKGSSSVHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------------------------------------------------
--------------------------------M

PF00069 // ENSGT00920000148982_1_Domain_0 (154, 332)

EVAVLKK-LQGKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTVSTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSVFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSIFDNSIKAFG
VIESDPFDWEKTGTDGSLTATTTSTTPQPHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGFPAAVSPDRVPGSPGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
EHSHDQANCILHAPSLGSPIRVRSETAQPDRDARLVRRLRSIHSLELEKRLTLEPKPDTD
RFLETCLEKMQKDSSAGKGS----AVPALLQKPC-LPAGSRMDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSREWVIVDKEQDLQEFRTHEALGHKTTGSPS
DEEPEELQVLEESPQEEELQLGPWAGND-LLGKEPTGVVLALSAECPATAPSEQCTNRLQ
LQAGAASHFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQH-LEK-KDLQPMEPTVELYSPRENFSGLVVTEGE----------GLQ
IDHAGQDMSP---RVRESDRSQDLGPKD---------LPE--DDRLVARGFENFTV-ETE
EKSFLLGS-GPEDAELSKEEHCVEV-A--LQGDTVTVAKDHST-TADPLEETRTQTFSVV
PDQDRNQEIMKLLAVGTSEFAPRVIDPHVEGQ-QGKVAAMQKSRPSE-DDDLKTEDLPEH
QGGLSALLHQEDKREQSALRNGELVHCILRHECTPPARKDVVRSSLGTRHSRIPVLAQEI
ESAFESSSPISAKEKLLQKKAYQPDLVRLLVEKRQFHSLLGDLSSASEKVLEEKLAAVPV
PFSEEDVFMPFSRLAVDAPLSRSAEDSFLSPLLSQARKSKIPRPVSWVSTDPVSSSPSSQ
FLPRPPPGKPPARPGLEARLRRYRVLGSSNSDSDLFSRLAQILQNGS--QKPRSSTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HEQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-RSSPKGSSSLHHHPASSKAPPGK----SKPASKLS
R

------------------------------------------------------------
-------------------------------MESLFKDWGWG-------LWRNLRCLGHA
HQGECCTEGGI------------SSTTKTSSENGGCC-------FEKAAR

PF00069 // ENSGT00920000148982_1_Domain_0 (171, 332)

FIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 394)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYRVSTSGPQAFSSLSYMS

PF16208 // ENSGT00920000148982_1_Domain_1 (394, 486)

GP-GACISSSSFS-------RVGSSSF
WS----GCGRASG--MGGITAVT-VNQSLLSPL-------------------NLEMNPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VYS

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 677)

QEKEQIKSL-NKFASFIDKVRFLEQQNKMLETKWSLLQQ--QRMARSNMNDM
FESYINNLRRQLET-------LGQEKLKLEAELGN-----------------MQGLVEDF
KNKYEEEINKRTEMENEFVLIEKAVDEAYMNKEGLTD--K----I-----SFLRQLC---
-EEEIG----------

ENSGT00920000148982_1_Linker_2_3 (677, 736)

SCSPRSWT--RLWCCPFTTA---------AS-WTWTASSRRS--
RPEDF-----PGGHH

PF00038 // ENSGT00920000148982_1_Domain_3 (736, 840)

HRCRLAVKNANAKLSELEAALQQAKQDVAQQLLV-----------
-------------YQELMN-----------------VKLALDVEIATY--RKLPEGEESR
LESGMQNMSIHVKITSSYVG-GQSLAYGG---------LTSPGLSYSLGSSFVCGVGSSS
-------------------------------------------FSRIIVAAPPRLIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAASLGSPVRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPMEPTVELYSPRENFSGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLP---NIRESNKSQDLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCMEISS--LPGDLVIVEKDHSA-TTEPLHVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISPRDIDPHVEGQ-IGQVAEIQKNKVSK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTSQSKS
PGSPHNAKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 338)

WKVLRKIGGG
GFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPQEFNIFLDHISNLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LMSVFDNSMKTSG
VIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPIGVSPEKLPGSSGHQRPQE-KDVWEEM-DANRNK-IKLGLCKASTEE
ENSHGPVNGILNAPSLGSPVRVRSETTQPDRDVPLMRKLRAIHSFELEKRLTLESKPDTD
KFLETCLQKMQKDSRAGKESAVAAPPPSLPQKISVPALAARTDHVWHYDEEYLPDASKPT
SASSPEQVDGIVSNGFVAVNLSSCRQEVDSKEWVIVDKERDLKDFRTNGALVHKTTGSPS
DEEPEELQVLEESPQEEHLRLGTWAENNVHAKNEASGVGLDLAIDHA-TAASERFTDKLE
FMAGAAGQFLAATPSSPMEAQAEGALTLLNSSHMLHFSTPRISSPFLCTLSHIAHLSSHL
DPKKEAGLPRSQSAESHSSSSCSTGRRQLPVIPSGNKFPPVIRISKAQLQQITIPRPSVA
STQSASESFHYGYQLEKRDRDTHALEHNVEFSSPKENLPGLVETEDALPPASSRTDLVLQ
LNHE---AFEREEHIKECVRLMSCGQK---------DLLEQCSSREEEKEPENLPI-ET-
EDRILPGVCEDAIEMSHKRQ------SSSPPGSSKFLERKPPV-AIESADESQPRPSCLM
SNSDANYEVQKSGAAETSDISPSRVIDLFTDRQENHMIVGQENGFHANEEIDHSEDLECH
QMDFSTFFHQEGKEEKHALRNGELFHCISENESSHQSKKDLVRSSFAVRQSRIPVLAQEV
DLTSESTSPVSAKEKLFLKKAHQTDLVRLLVEKRQLKSFLGDLSSASDKSLEEKVAAAPV
PFSEDDVLCSFSRLTLDSHLGKQSEEGSLSPSSSQCRKSKIPRPVSWATTDQVTNSTSAQ
FFPHPPPGKPPMRPGVEARLRRYRVLGSSNSDSDLISRLAQILQNGS--QKPRSSTQCKS
PGSPHSPKTPPKSPVIPRRSPSASPRSSSLPRTVSSSPSRAGRPH-HDQKNSSPHLGRSK
SPPSHSGSSSSRRSCQQEHFCSKPSKNGLKGSNSSCHHSPNTKTPTGK----SKSASKLS
R

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------GRNLADLR

PF00069 // ENSGT00920000148982_1_Domain_0 (197, 284)

RSQARGTFTVSTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNRVTQRHKRL
HCKQAVV-----SSIPGTNKKGKRPKK----------------------------EKKER
KKERKL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDKSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGMPVGVSPDRLPGSPGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSETTQPDRDAPLLRKLRSIHSFELEKRLTLEPKPDTE
KFLETCLEKMHKESSAGKGA----VMPALLQKPC-PSAASRTDHVWHYDEEYLPDASKHA
SAHTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLQLGPWAGSG-HLKKEPSDVVLALSVECPATAPAEQDPDRLE
LQAGVASQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AVRDLFLC--
----------------------------------------YSVTHSR----------C--
---------------------------------------L--QKTDIGREFENFPV-ETE
EK-IIPGA-DNEDEKLSREQYCVE-LS--LQGDLGTEEKDHSA-TTEPLDGTKTQTFSVV
PNQDRNHEIVRFLAAGTSELSPTVIDPPVEGQ-HGQVAAVQKSRLPK-GDDIQMEALPEH
HEGLSALLCQEDKREKSAPRNGELIDCIAESERAPPARKDVVRSSLVTRHSRIPVLAQEI
ESAFEASSPVSAKEKLLQKKAHQPDLVRLLVGKRQLRSLLGDLSSASNKLLEDKLASVPV
PFSEEDVLVPFSKLAVDAPLSRSAEDNFLSPISSQSRKSKIPRPVSWVSTDQVSSSLSSQ
FLPRPPPGKPPARPGVEARLRRYRVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTPCKS
PGPPHNPKTPPKSPVVPRRSPSASPRSSPLPRTSSSSPSRAGRPH-HEQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-RGSPKGSGSLHHHPASSKAPLGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPAGVSPDKLPGSLGHPRPQE-KDVWEEL-DANRNK-IKLGVFKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLALEPKPDTD
KFLETCLEKMQKDSSAGKEA----LLPALLHKPC-VPSVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDDKLRLGPWAEND-HLKKETSGVILALSRECPATAASEQYTDRLE
LQAGAAGQFIAVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLHPMEPTVELFSPRENFSGLVVIEGEPPSGGSRTDLGLQ
MDHTGHDVLPNI---RECDRPQDLGPKD---------LSDH-DR-PALGEFEGLPR-EKE
GKSILLGS-DNEDEKLSKKQHYIEIAP--LPGDLVTVERDHTA-TAEPLDAIKTQTFSVV
PNQDKNHEIMKLLAVGTSEISP-HVTDPHVEGQIGQMAAMQKSKISK-DDDLKSEDLPRH
QGDLSTFLHQEGKREKMAPRNGELFHSVSESDHCPPSRKDVVRSSFVTRHSRIPVLAQEI
DSAFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKLLEERLATVPA
PFSEEQVFTPFSRLAVDSHLSRSAEDSFLTPIISQSRKSKIPRPVSWISTDQVNSSTSSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH--DQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSSGLHHHSASTKAPPGK----SKSASKLS
R

----------------------NFKTGKIKCLLKETHFW---------LRREVGTRLNGN
HPWELDACVAVLPHQYFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFKM
GRFPSTCRKCFMLDFGLARQFTYSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKNKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESEPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLAHARPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGHVNGILNAPSLGSPVRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCMEKMQKDSSAGKE----SVLPALPHKPC-VPVVSRTDHIWHYDEEYLPEASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLKDFRTNEVLGHKTTGSPS
DEEPEVLQVLEGSPQDEKMQVGPWTDNH-HLK-ESSGVVLALSAECPATAASEQYTDRLD
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGPQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGELPSGGSRMDLGLQ
IDHIGHDMLPNM---RDGDISQDLGPKD---------LPDH-NR-LVVKEFENLPG-ETE
EKSI-LGS-DNEDEKLSKGQHCVEIS---LPGDLVTTERDQSA-TTEPLDGLKTQNFSVV
PNEDKNHEIMKLLAVGTSEIS--QVIDPHAEGQIGQVAVMQKTKLFK-GTDIKSEDLPGH
QGDLSTFLHQEGKRDKIVPRNGELYHCVPESEHCPPTRKDMLRSSFVTRHSRIPVLAQEI
DSTFESSSAVSAKEKLLQKKAYQPELVKLLVEKRQFKSFLGELSSASDKLIEEKLAAAPV
PFSEEEVFTPFSRLAVDSHLSRSAEDGFLSPIISQSRKSKIPRPVSWVSTDQVNSSASLQ
FLPRPPPGKPPIRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTPQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGPKGSGSLHHHSASSKTPPGK----SKPASKLS
R

MGLANRRHGLGTCSPISTRGGENCKTGKIKCLLKETHSW---------LRREVGHRLNGI
HPWELDACVAVLPHQGFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDREVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCMEKMQKDSSAGKEP----VLPALPHKPC-VPVVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEVLGHKTTGSPS
DEEPEVLQVLEGSPQDEKIQVGPWTDNH-HLKKESSGVVLALSAECPATAASELYTDRLD
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGPQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGELASGGSRVDLGLQ
IDHTGHDMIPNM---RDGDTSQDLGPKD---------PPDH-NR-LAVKEFEHLPG-ETE
EKSVLLGS-ENEDEKLNEGQHCIEIS---LPGDLVTAERDQSA-TTEPLDVSKTQNFSVI
PNQDKTHEIMKLLAVGTSEISP-QAIDPHPEGQIGQMAAMQKNKLFK-DDGIQSESLPGQ
QGDLSVYLHQEGKREKVVPRNGELYHCVSENEHGPPTRKDMLRSSFVTRHSRIPVLAQEI
DSTFESSSAVSAKEKLLQKKAYQPEIVKLLVEKRQFKSFLGDLSSASDKLIEEKLAAAPV
PLSEEEVFTPFSRLAADSHLSRSVEDSFLSPVISQARKSKIPRPVSWVSTDQINSSASPQ
FLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGPKGSGSLHHHSTSSKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 335)

WKVLRKIGGG
GFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHICRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFIVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPTEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSVGHPRPQE-KDVWEEM-DVNRNK-IKLGICKAATEE
ENSHGPANGILNAPSLGSPIRVRSETTQPERDVPLVRKLRSIHSFELERRLTLESKPDTD
KFLETCLEKMQKDSSVEKEPV---IPASLLHKPC-TPAVTRTDHIWHYDEEYLPDASKPA
SANSPEQADGGGSNGFIAVNLSSCQQEVDSKDWVIVDKERDLHDFRTNGALGHK-TGSPS
DEEPEVLQILEESPQEEQHKLGPWVEDS-HQKNGAPEVVLTLSVACPGTAVSEQYADRLE
LQAGAAGQFLAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------PVTIPRPSVA
STQSTSGSFHYGQALEK--KDLQPLEHTVELYSPKENVSAVVGTEGELPSGASRTDWVLP
LDHLGQDNTPREDLTRECVKSQDLVQKE---------LPDH-NIKVAAKEFETLPVVGAE
EKSTVLGS-DNEEEKLGKGHCFIEIAN--LPGDLEREHS----STPELLEEFRTRTFCLV
PDQDTNHEIMKLLAGATSEISPARVIHPHGEGQIGQVMVQKSKLQRD-EDISKGEGVPSH
QGDLSAFLHQEGKKEKISPRNGELFHCISENEHSPTSRKDVIRSSFITRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKSLEEKLAGVPV
SFPEDEVFTPFSRLAIDPHLSRSAEDSFLSPLSSQARKSKIPRPVTWANPDQVSNSASAQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRGSTQCKS
PGSPHSPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCCLKSSKNGMKGSGSLYHHSASPKTPQGK----NKSASKLS
R

MGLINRRCELERCFPISTRG----------------------------------GELNGN
HLWELDARVAVLPQQCFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGLPAVVSPDRVPGSPGYCRAQE-KDVWEEM-DAKKNK-IKLGICKAATEE
EHSHGQANGVLHAPSLGSPVRVRSETAQPDRDTRLVRRLRSIHSLELEKRLTLEPKPDTD
RFLETCLEKMQKDSHTGKGS----AVPALLQKPC-LPAMSRTDHVWHYDEEYLPDASKPA
SANTPEQADGGGSHGFIAVNLSSCKQEVDSREWVIVDKEQDLQDFRTNEALGHKTTASPS
DEEPEVLQVLEESPQDEKLQLGPWVGND-HLGKEPSGVVLGLSAGYPAAAPSEQCTDRLE
LQAGPTSQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQHLEK--KDLQPMEPTVELYSPRENFSGLVVTEGE----------GLQ
IDHVGQDMMSP--CVRESDRSQDLGPKD---------LPD--DDGLVVREFENFPV-ETE
EKSLLLGS-DHEDEKLSKEEHCVEVA---LRGDRVTVEKDHST-TPDPLEVTRTQTFSVL
PNQDRNHEIMKLLAVGTSEFSPRVIDPHVEGQ-QGQVAPMQKSRPCK-NDDIKTEDLPEH
QGGLSALLCQEDKKEKSALRNGELVHCVSQNECAPPARKDMVRSSLGTRHSRIPVLVQEI
ESAFELSSPVSAKEKLLQKKAYQPDLVRLLVEKRQFRSLLGDLSSASEKVLEEKLAAVPV
PFSEEDVFMPFSRLAVDATLSRSVEDSFLPPLLSQARKSKIPRPVSWVSTDPVSSSPSSK
FLPRPPPGKPPARPGVEARLRRYRVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HEQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP--SKSSPKGSGGLHHHPGSLKAPAGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 270)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIK------
-----------------------------PPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETWYEIVFLFFKATKKDA-IVILNIII--------------INFYNVKSFK------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------WK

PF07714 // ENSGT00920000148982_1_Domain_0 (113, 336)

VLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLEHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKAFG
VIESDPFDWEKTGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDMLRENTDEVF
PDEQLSDGENGIPVGVSPNKVPGSLGHPHPQE-KDVWEEM-DTNRNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLALEPKPDTD
KFLETCLEKMQKDPSAGKES----TLPALLHKPC-VPAVSRADHIWHYDEEYLPDASKPA
SVNTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEALGPKTTGSPS
DEEPEVLQVLEESPQDEKLQLGPWAEND-HLKKETSGVVFVLSGECPATAASEQYIDRLE
FQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLHTIEPTVELYSPRENFSGLVVIEGEPPSGGSRTDLGLQ
IDHIGHDMLP---NIREYDRSQDVGPKD---------LPD--HNRLAMREFEGLPR-GLE
EKSIALGS-DNEDEKLSKGQHYIEISP--LPGDLVTMERDHSA-TTEPLDVTKMQTFSVV
PNQDKNHEIMKLLAVGSSEVSPRVIDPYVEEQ-IGQVAAMQKSKIS--EDDIKGEDLPNH
SGDLSTFLHQEGKREKIAPRKGELFNPVSESEHCPPSRKDVVRSSFVTRHSRIPVLAQEI
DSTFDSSSPVSAKEKLLQKKACQPDLVKLLVEKRQLRSLLGDLSSASDKLLEERLATVPA
PFSEEEVFTPFSRLAADSHLSRSAEDNFLAPIISQSRKSKIPRPVSWVNTDQVNSSTPSQ
FLPRPPPGKPPMRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGTPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSFHHHSASTKAPPGK----SKSASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSIGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTITTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVCVSPDKLPGSLGQPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKE----SILPALLHKPC-IPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQGDGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEVVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAALEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHVGHDMLPNF---RESNQSQDLGPKE---------LPDH-NR-LVVGEFENLPG-ENE
EKSILLES-DNEDEKLSRGQHCVELSS--LPDLL-MVEKDHSA-TTEPLDVTKTQNFSVV
PNQDKNKEVMKLLTVGTSEISP-RDIDPHVEGQIGQVAEMQKSKISK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSFPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
SFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSANTKTTPGK----SKPASKLS
R

------------------------------------------------------------
-----------------------------------------------------L

PF00069 // ENSGT00920000148982_1_Domain_0 (115, 332)

RKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VTESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGMSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDAD
KFLETCLEKMQKDSSAGKE----SILPVLLHKPC-VPTVSHTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSYKQEIDSKEWVIVDKEQDLQDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQGEKLQLGPWAEND-HVKKEASGVLLELSADCPASAASEQYVDRLE
LQAGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQQLEK--KDLQPMEPTVELYSPRDNFSGLVVTEGEPPSGGSRADLGLQ
TDQIGHDILPNI---RESDKSQDLGPKD---------RPYH-NR-LVGREFENLPG-ETE
EKSILLGS-DNEDEKLSKRQHCVEISP--LPGDLVTMEKDHSA-TTEPLDVTKAQTFSVL
PNQDKNHEIMKLLAVGTSEISP-RVIDSHVEGQIGQVAAMRKSKLSK-DDDIKSEDLPGH
QGDLSTFLQQGGKREKTAPRNGELFHCVSENEHCPPTRKEVVRSSFVTRHSRIPVLAQEI
DSTFESSSAVSAKEKLLQKKAYQPDIIKLLVDKRQFKSFLGDLSSASDKLLEEKLATVPA
PFSEEEVFTPFSRLAVDSHLSRSAEDSFLSPVISQSRKSKIPRPVSWVNADQANSSTSSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGTLHHHSASTKTPPGK----NKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 270)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIK------
-----------------------------PPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGLPIGVSPDKLPGSLGHTRPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETWY-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MQLQGR

PF07714 // ENSGT00920000148982_1_Domain_0 (191, 335)

NLADLRRSQARGTFTLSTALRLGRQILEAVESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFGIFLDHISSVDYFT
KPDYQV------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------STY----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
---------------------------------AVEEDWGWG-------LWRNLRCLGH

PF00069 // ENSGT00920000148982_1_Domain_0 (120, 405)

A
HQGKCCTEGRI------------SSTTKTSSENGGGCIEKTT-RKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVIIFVSSV-VFVLAYSFEGIVN----ECGRSLVCLLLNRFY-------CSCCDS-
-----LVYRTADGS-N----YIN-PTVNLLTRS-------------------NVSV----
---KGLRA-VISYVHMLWNKFIIFICKVQHIDFTVKESFTFYSVISLPSQKTINSTLKHS
PLSYVCNLKKTINK-------LHMANTSSNSPLGLTLTADVEREAVLLFTRKCYGVLGNY
IQVYQYIVFM-YNLPNSLL---------------LRKSKK----NQLLTKKMLGQHF---
-QKSLG----------MGLFKQRL--HQKFCAFNPS---------AS-CCWSLVSPCS--
-AFSG---RGLSA-HTQDRCCLMDGAPPVRRHAACLV--RTSISRVRREVQGVPLLFPYA
GSQSILLSCVFSNFESLVNKNMTRTKFLGFITMPFPIPFIFLVSFSPF--FSLWESSKFW
N-----------------------------------------------------------
---LKAKKSVVIVVFFNPTTKLICECGGFLLN--------KMTVFILLTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDAD
KFLETCLEKMQKDSSGGKES----VLPALLPKPC-VPTVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGASNGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLLLGPWAESD-QLKKEPSGVVLALSGECPATAASEQHTDRLE
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPVEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHTGHDLLP---NIRDCNKSQDLGPKG---------LPD--HNRLAEREFENLPR-DTE
EKSNLLGS-DNEDEKLSKGQHYIEIAS--LPGDLVAAERGHSA-TTEALDVTKTQTFSVG
PDQDKSHEVVKLLAVGTSEISSRVIDPHVEGQ-ISQAAAMQKSKLSK-DDDIRSEDLPGQ
QGDLSTFLHQEGKREKMAPRNGELFHCVSESEHCPPSRKDVIRSSFVTRHSRIPVLAQEI
DSAFESSSPVSAKEKLLQKKAYQPDLVRLLVEKRQLKSFLGDLSSASDKLLEERLATVPA
PFSEEEVFAPLSRLAVDSHLSRSAEDGFLSPIISQSRKSKIPRPVSWVNTDQVSSATSAQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTAQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSSSLHHHSASTKAPPGK----SKSATKLS
R

-----------------------------------EEDWRW-------------------
------------------------------------GL------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 359)

WRNLRCFGHA
YQRKCCTEGRISSTTE-----------TSFENGGCCIEKTTX-XKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTVSTTLRLGRQILESIESIHSVGFLHRDIKPXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-----------------
---XXXXXXXXXXX--------------XXXXXXX--XXXXXXXXXXXXXXX--------
XXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-XX-----------------------XXXX-XXX-------XXXXXXXXXXXX-------
--------XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------
--------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFEL-ERLTLEPKPDTD
KFLETWLMKKQKDPSAGTRS----LLPTLLHKRC-VPVRIRVDY-IHYDEEYLPGASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTASPS
DEEPEVLQVLEESPQDEKLQLGPGAEDD-PLKKETPGVVLAVSEECPAIAVSEQYTDRLE
LQAGTASQFIAVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQHPEK--KDLQPMEPTMELYSPRDNFSGLVVTDGEPPSGGSRTDLGLQ
INHTSHDMLTSV---RECDRSQDLEPKD---------LPDQS--RLAEKEFERLPR-ETE
EKSILLGS-ENEVEKLSKGQH-IEISS--LPGDLVTLEKDRSA-TSEPLDVTKTQTFSVV
PNQDRNHEIVA---VGSSEIPP-RATEPHVEGEVGQGATAQKGKMPK-DDDRKNEDLPSH
PRDPSTFLHQEGK-EKNAPRNGELFHCVSENEHCPPPRKDVVRSSFVPRHSRIPVLALET
DSSFESSSPVSAKEKLLQKKAYQPDLVRLLVEKRQLKSLLGDLSSASDKLLEERLATVPA
HFSEEEVFTPFSRLGVDSHLSRSTEDNFLSPIISQSRKSKIPRPVSWVNTEQVSSS-TSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTAQCKS
PGTPHNSKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRVGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHYK--PSKNGLKGSSSLHHHSVNTKAPPGK----SKSASKLS
R

-----------------------------------EKD----------------------
---------------------------------WGRWF------------WRNLRCSGY

PF00069 // ENSGT00920000148982_1_Domain_0 (120, 359)

A
HQGKCCTEGGVGSTA------------KTSSENGGCCSEKTT-RKDHVCRFVGCGRNDRF
NYVVMQLQGRNLADLRRSQVRGTFTIGTTLRLGRQILESIESIHSVGFLHRDIKPXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPRAMAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSVFLDHISSLDYFT
KPDYQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-----------------
---XXXXXXXXXXX--------------XXXXXXX--XXXXXXXXXXXXXXX--------
XXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-XX-----------------------XXXX-XXX-------XXXXXXXXXXXX-------
--------XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX--XX
XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------
--------------------------------XXXXXXXXXPGEKKLLTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDTD
KFLETCLERMQKDSSAGKES----VVPALHHKPG-VPVVSRGDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKDWVIVDKEKDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEDSPQDEKLQLGPWAEND-HLKKETSDVVLALSAEHPATAAAEQYTDRLE
LHVGATGQFLAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPKENFSGLVVTEGEPPSGGSRTDLGIQ
IDHIGHDLLPNI---VESDRSQDLGPKD---------LPDQN--RLNVREFENLPG-ETE
E-KSILGS-DNEDEKLSKGQHCIAISS--LPGDLVTMERDHST-TTEPLDVAKTQTFSVV
PNQDKNHEIMKLLAIGTSETSP-TVIDPHIEGQIGQMATGHKNKIGK-EDDIKSEDLLGH
QGDLSSLLHQDGKREKIAPRNGELFPCASENEHGPSTRKDVVRSSFVTRHSRIPVLAQEI
DSSFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFRSFLGDLSSASEKLLEEKLATIPT
AFPEEEVFTPFSRLATDSHLSRSAEDSFLSPMVSQCRKSKIPRPVSWVNTDHVSSSTSSQ
FLPRPPPGKPPSRPGVEA------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VTENDPFDWEKTGTDGSLTTTTTSTTPQMHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGMSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDSSAGKE----CILPVLLHKPC-VPTVSHADHVWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQGEKLRLGPWAEND-HFKKEASGVVLELSGECPATAASEQYIDRLE
LQAGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQQPEK--KDLQPMEPTVELYSPRDNFSGLVVTEGEPPSGGSRTDLGLQ
TDHIGHDILPNI---RESDKSQDLGPKD---------RPDH-NR-LVGRELENLPG-ETE
EKSILLGS-DNEDEKLDKRQHCVEISP--LPGDLVTVEKDHSA-TTEPLDVTKTQTFSVV
PNQDKNHEIMKLLAVGTSEISP-RVIDPHVEGQIGQVAAMQKSKLSK-NGDIKSEDSPGH
QGDLSTFLQQGGKRDKIAPRNGELFHCVSENEHCPPTRKEVVRSSFVTRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDIVKLLVDKRQFKSFLGDLSSASDKLLEEKLATVPA
HFSEEEVFTPFSRLAVESHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQTNSSTSSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPPGK----NKPASKLS
R

------------------------------------------------------------
-------------------------------MESVEKNRGWG-------L

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 359)

WRNLRRLGLA
HQGKCCLESRI------------SSTTKTSSENGSRCVEETAXXXXXXX-XXXXXXXXXX
XXXXXXXXGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPTEFSVFLDHISSLDYFT
KPDYQXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXX
XXXXXXXXXXXXX-------XXX-XXXXXXXXX-------------------XXXX----
---XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXXXX
XXXXXXXXXXXXXX-------XXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX-XXX-XX----XXXXXXXXXXXXX---
----------------XXXXXXXX--XXXXXXXXXX---------XX-XXXXXXXX----
-XXXX-------X-XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXX---XX-XXXXX
---XXXXXXXXXXXXXXXX----XXXXXXXXXXX-XXXXXXXXXXXXX--XXXXX---XX
X------XXXXXXXXXXXXX-XXXXXXXX---------XXX-XXXXXXX--XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNELLTSVFDKSIKTFG
VAESDPFDWEKSGADGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSVGHPRPQE-KDVWEEM-DVNRNK-IKLGICKAATEE
ENSHGPANGMLNLPSLGSPIRVRSETTQPERDVPLVRKLRSIHSFELERRLTLESKPDTD
KXXXXXLEKMQKDSSVEKEPVL---PASLPHKPC-APAVTRTDHIWHYDEEYLPDASKPA
SANSPEQADGGGSNGFIAVNLSSCQQEVDSKDWVIVDKERDLHDFRTNGALGHK-TGSPS
DEEPEVLQILEESPQEEQHELGPWVEDG-HQNNGTPSVVLALSVACPATAASEQYADRLD
LQAGAAGQFLAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------PVTIPRPSVA
STQSTSGSFHYGQPLEK--KDLQPLEHTVELYSPRENVSGVVGTEGELPSGASRTDWVLP
LDHLGQDSTPKEGLTKECVKSQDLLP-------------DHNNIKMATKEFETLPV-GAD
EKSVVLGS-DNEEEKLGKGHCFIEISN--LPGDL---EREHSH-TPEPLEEFRTRTFCVV
PNQDTNHEIMKLLAGATSEISPARVIHPHGEGQIGQ-GVVQKSKLQRDEDIRKGEDVPSH
QGDLSAFLHQEGKKERISPRNGELFHCISENEHSPTSRKDVIRSSFITRHSRIPVLAQEI
DSSSETSSPVSAKEKLLQKKAHQPDLVKLLVEKRQLRSFLGDLSSASDKVLEEKLAAVPA
PFPEDEVFTPFSRLALDPRLSRSAEDSFLSPLSSQVRKSKIPRPVTWANTDQVNNSASAQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRGSTQCKS
PGSPHSPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCCLKPSKNGMKGSGSLYHHSASPKTPPGK----SKSASKLS
R

------------------------------------------------------------
-------------------------------MESVEEDWRWG-------L

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 359)

WRDLRCVGHA
YQGECCTEGRI------------SSTAKTSPENGGCCTEKTT-RKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXX
XXXXXXXXXX-----XXXX-XXX-XXXXXXX-X-------------------XXXX----
---XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXX-XXXXX
XXXXXXXXXXXXXX-------XXXXXXXXXXXXXX----------XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX--XXXXXXXXX--X----X----XXXXXXXXXXXXX---
-XXXXX----------XXXXXXXX--XXXXX--------------XX-XXXXXXXXX---
-XXXX---XXXXX-XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXX-----XXXXXX
---XXXXXXXXXXXXXXXX----XXXXXXXXXXXX-XXXXXXXXXXXX--XXXXXXXXXX
X------X-XXXXXX-XXXX-XXXXXXXX---------XX---XXXXXX--XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLPTKNKLLTSVFDNSIKTFG
IVESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLVQPHPQE-KDVWEEM-DVNRNK-IKLGICKATTEE
ENSHGQANGMLNAPSLGSPIRVHSEITQPDRDVPLVRKLRSIHSFELEKCLTLEPKPDTD
KFLEACLEKMHKDSSAGKES----TLPDPLYKPC-VPAVSRTDRIWHYDEEYLPDASKPA
SANTPEQGDGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEVLGHKTTGNPS
DEEPEVLQVVEESPQDEKLRIGPWAENE-NLKKETSGVVLALSGEGPATAASEQYTDRLE
LHAGAGGQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSISGSFHYGQQ-PEK-KDLQLMEPTVELYSPREKFSGLVVTEGEPPSGGSRTDLGLQ
LDHIGHDMLPRGVHIRGYDKSQDLGQKD---------LPD--HSRLVVREFESLLG-EIE
EKSHFLGP-VNEDEQLSKGQCCVEISR--IPGDLLTIERDQST-TAEPVDVTKIQTFSVM
PNQDKNHEVLKLLPVGTSEISPRVINPGVEGQ-MGHVAAMQKRKISK-DDDIKNEDLPGH
QGDLTTILHQEGKREKIAPRNGELFHCVSENEHCPPSRKDTSRSSFVTRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKPFLGDLSSASDKLLEEKLADVPA
PFSEEELFTPFSRLAVDSHLNRSAEDNFLSPIISQSRKSKIPRPVSWINTDQVSSSTSSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTTQCKS
PGSSHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAARPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSVSTKTPPGK----SKTASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTINTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHRRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPREN-SGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLPNI---RESNKSQDLGPKE---------LPDR-NR-LVVREFENLLG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKDHSA-TTEPLNVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISP-RDIDPHVEGQIGQVAETQKNKVSK-DDDVMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTQKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSLLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PASPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 235)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPVGSQH
----------------LSRAF--------SQSSVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGQPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRMTLESKPDTD
KFLETCLEKMQKDTSAGKE----SILPALLHKPC-VPAVSRTDHIWHYDDEYLPDASKPA
SANTPEQGDGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLEDFRTNEVVGHKTTGSPS
DEEPEVLQVLEVSPQDEKLRLGPWAEND-HLKKETSGVVLAFCAEGPPTAASEQYTDGLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
LDHIGHDMLPNF---RESNQSQDLGPKE---------LPDH-NR-LVVGEFENLPG-ESE
EKSILLES-DKEDEKLSRGQHCVELSS--LPDLLM-VEKDHSA-TTEPLDVTKTQTFSVV
PNQDKNKEVMKLLTVGTSEMSP-RDIDPHVEGQIGQVAEMQKSKISK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLELSFPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
SFCEEEVLTPFSRLTVDSHMSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSP
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSANAKPPPVK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPAGVSPDKLPGSLGHPRPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCMEKMQKDSSAGKEP----VLPALPHKPC-VPAVPRTDHVWHYDEEYPPDASKPA
SANTPEQADGGGSHGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEVLGHKTTGSPS
DEEPEVLQVLEGSPQDEKIQVGPWTDNQ-HLKKESSGVILALSAECPATAASELYTDRLD
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGPQPEK--KDLQPLEPTVELFSPRENFSGLAVTEGELGSGGSRVDLGLQ
IDHIGHGMLPNM---KDGDASQDLGPRD---------LPDS-NR-LVVKEFENLPG-ETE
EKSILLGS-DNEDEKLNKGQHCIEI-S--LPGDLVTTERDQSA-TTEPLDVSKTQNFSVV
PNQDKNHEIMKLLAVGTSEMSP-QAIDPHAEGQIGQVATVQKHKLFK-D-DTKSESLPGQ
QGDLATFLHQEGKREKVAPRNGELYHCVSESEHGPPTRKDMLRSSLVTRHSRIPVLAQEI
DSTFESSSAVSAKEKLLQKKAYQPEIVKLLVEKRQFKSFLGDLSSASEKLMEEKLAAAAV
PFSEEEVFAPFSRLAVDPQLSRSVEDGFLSPIVSQSRKSKIPRPVSWVSTDQINSSASPQ
FLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGPKGSGSLHHHSASSKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 334)

WKVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKEA----ILPALLHKAC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAAGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPRENFSGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLPNI---RESNKSQDLGPKE---------LPDH-NR-LVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKDHSA-TTEPLNVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISP-RDIDPHVEGQIGQVAEIQKNKVSK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLMEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVMRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTHRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DVNKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDREVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTGTGKES----VLPAVLHKP----TVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSYKQEIDSKEWVIVDKEQDLQDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLRLCPWAKND-HLKKETSGVVLPLSTECPATAASEQYTDRME
LQAGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPVEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLVPQ
IDHTGHDMLPNI---RESDKSQDLGPKD---------LPDT-NR-LVVKEFENFPG-ETE
EKSILLES-DNEDEKLSKGQHCIEISS--LPGDLVTVDKYHSATTSEPLDVTKTQTFSVV
PNQDKNNEIMKLLVVGTSEVSP-RVIDPHIKGQVGQVTAVQKSKIPK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGPPTRKDMVRSSFITRHSRIPVLAQEI
DSPFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKLLEEKLATVSA
PFSEEEVFTPFSRLTVESHLSRSAEDNFLTPIISQSRKSKIPRPVSWVNTDQVNSPTSSQ
FLPRPPPGKPPARPGVEAR-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------MSGGGEQPDILTVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 270)

KVLRKIGGG
GFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIK------
-----------------------------PPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPQEFNIFLDHISNLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LMSVFDNSMKTFG
VIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPEKLPGSPGHQRSQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGPVNGMLNAPSLGSPVRVRSETTQLDRDVPLVRKLRSIHSFELEKRLTLESKPDTD
KFLENW------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

PF00069 // ENSGT00920000148982_1_Domain_2 (164, 1176)

GRDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMVVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTPPQLHTRVTPAAIG-IANATPIPGDLLRENTDEVF
PDERLSDGENGVPVGLSPDKSPGSLGHPRPQE-QDVWEEM-DASRNK-IKLGICKAATEE
ENSHGQANGLLNVPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLESKPDTD
KFLETCLEKMQKDSSGGKES----TLPALLHKPC-VSVMSRMDHVWHYDEEYLPDASKPA
SVNTPEQPDGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLRFSPWVEND-HLKKESSGVLLALSGECPVTAASEQYTDRLE
LQAGTASQLIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITAARPSVA
STQSTSGSFHCQQ--LEK-KDLQPMEPTVELDSPRENLSGLVVTEGEPASGGCRTDLGLQ
LDHIGHDMLSKEAPIRECDRSQDLAQRD---------PPD--HRRLVVKEFDSLPG-ETE
EKSVLVGS-DNEDEKLSKEQCCVEISP--LPGDLVTVERDQSA-TTKPLDVTKTQTFSVV
PNQDKNHEIMRLLAIGTSEISPRVIDPYVEGQ-MGQVAALQKSKVPK-DDNIKSEDLLGH
QGDLSIFLHQEGKREKIAPKNGELFHCVSENEHYSPSRKDVVRSSFVTRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKLLGEKLATVPA
SFPEEEVFTPFSRLAVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWANTDQVNSATASQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPHRSPSASPRSSSLPRTSSSSPSRAGRPH-HDRRSSPPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KSGPKGPGSFHHHSASTKTPPGK----GKAASKLS
R

------------------------------------------------------------
-------------------------------MESVEEDWGWG-------L

PF00069 // ENSGT00920000148982_1_Domain_2 (111, 947)

WRNLRCLGHA
YQGKCCTEGGI------------SSTTKTSSENGGCCIEKTT-RKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRVVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQLHIQ---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NKLLTSVFDNSIKTFG
VTESEPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXXXXX-XXXXXXXAATEE
ENSHGHANGILNAPSLGSPIRVCSEITQPDRDVPLVRKLRSIHSFELEKRLALEPKPDAD
KFLETCLEKMQKDSSAGKES----LLPALLHKTC-IPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLRLGPWAEND-HLKNETSGVILALSRECPGTAASEQYADRLE
LQAGAASQFIAVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KGLHPMELTVELYSPRENLSGLVVTEGEPPSGGSRTDLGLQ
VDHIGHDTLP---NIRECDKSQDLGPKD---------LPD--HNRLAGREFESLPR-ETE
EKSILLGS-DNEDEKLNKGRHYVEISS--LPRDLVTVERDHSA-TTEPLDVTKTQTFSVV
PNQDKNHEIMKLLAAGTSEILPQVIDPHVEGQ-IGQVAAMQKSKLSK-DYEIKSEDLPSH
QGDLSTFLHQEGKREKISPRNGELFHSVSESEHCPPSRKDVVRSSFVTRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKLLEERLATVPA
PFAEEELFTPFSRLAVESHLSKSAEDSFLTPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FLPRPPPGKPPVRPGVEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-HDQRSSSPHLGRSK
-PPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKSPPGK----SKSASKLS
R

MGLINRRCELERCFPISTRG----------------------------------GELNGN
HLWELDARVAVLPQQCFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_2 (112, 969)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDK-------------------------------------
-----L------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGLPAVVSPDRVPGSPGYCRAQE-KDVWEEM-DAKKNK-IKLGICKAATEE
EHSHGQANGVLHAPSLGSPVRVRSETAQPDRDTRLVRRLRSIHSLELEKRLTLEPKPDTD
RFLETCLEKMQKDSHTGKGS----AVPALLQKPC-LPAMSRTDHVWHYDEEYLPDASKPA
SANTPEQADGGGSHGFIAVNLSSCKQEVDSREWVIVDKEQDLQDFRTNEALGHKTTASPS
DEEPEVLQVLEESPQDEKLQLGPWVGND-HLGKEPSGVVLGLSAGYPAAAPSEQCTDRLE
LQAGPTSQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQHLEK--KDLQPMEPTVELYSPRENFSGLVVTEGE----------GLQ
IDHVGQDMMSP--CVRESDRSQDLGPKD---------LPD--DDGLVVREFENFPV-ETE
EKSLLLGS-DHEDEKLSKEEHCVEVA---LRGDRVTVEKDHST-TPDPLEVTRTQTFSVL
PNQDRNHEIMKLLAVGTSEFSPRVIDPHVEGQ-QGQVAPMQKSRPCK-NDDIKTEDLPEH
QGGLSALLCQEDKKEKSALRNGELVHCVSQNECAPPARKDMVRSSLGTRHSRIPVLVQEI
ESAFELSSPVSAKEKLLQKKAYQPDLVRLLVEKRQFRSLLGDLSSASEKVLEEKLAAVPV
PFSEEDVFMPFSRLVVDATLSRSVEDSFLPPLLSQARKSKIPRPVSWVSTDPVSSSPSSK
FLPRPPPGKPPARPGVEARLRRYRVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HEQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP--SKSSPKGSGGLHHHPGSLKAPAGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------WK

PF07714 // ENSGT00920000148982_1_Domain_0 (113, 335)

VLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VSESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGIYKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLESKPDTD
KFLETCLEKMQKDSNAGKE----SVLPALLHKPC-VPAVSHTDRVWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEALVHKTTGSPS
DEEPEVLQVLEESPQGEKLRLGPWAEND-HFKKEISGVVLELSAECPATVASEQYIDKLE
LQAGVASQFIAATPTSQMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQLPEK--KDLQPVEPTVELYSPRENFSGLVGTEGEPPSGGSRTDLGLQ
IDNIVHDILPNI---KESDKSQDLGAKD---------LPDY-NR-LVGREFENLPG-ENE
EKSILLGS-DNEDEKLSKRQHCVDISP--LPGDLVTAKKDHSA-TTEPLGVTKAQSFSVV
PNQDKNHEIMKLLAVGNSEISP-RVIDPHVEGQIGQMVAVQKSKLSK-DDDVKSEDLPGH
QGDLSTFLHQGGKRDKIPLRNGELFHCVSENEHGPPTRKDVVRSSFVTRHSRIPVLAQEI
DSTFESPSTVSAKEKLLQKKAYQPDIVKLLVEKRQFKSFLGDLSSASDKLLEEKLGTVPV
PFSEEEVFTPFSRLAVDSHLSRSAEDSFLSPITSQSRKSKIPRPVSWVNTDQVNSSASSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHIPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRSGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
-------------------------------SYAVEEDWGWG-------L

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 380)

WRNLRCLGHA
YQGKRCTEGRI------------SPTTKTSSENGGCCVEKTT-RKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHKLMLKHLPPEFSIFLDHISSLDYFT
KPDYQLEKRPTQV-LENVMVFGDTIYKFISQNTGC-GIIFHIKSFL-------KSAWPTF
FKKSSEWYLGKSL----STLTST-TGLHLYVPL-------------------LMLIELHD
---SDIRTQKVSLLECSDYQFSEGI-DERLMKQTNKNLSTKFSLDVQS-QPLPVPCPGTL
TMSYKAICRWLLLV-------LGLEMPRRGQAMNQVV-------CIQMKQKRIRGYLGRY
RERLNYAL----ERKNIFLNSSPFSPIAAMYKHFVKSSRN----SLKVSIKYIKCLNSE-
-QNSSG----------SCATFITL--EAWCMDWCTL---------KGGVPWPGLACRNQA
ET--GS------PTSPEGSQTVRGHSAKLLDYSCCTQFISTHTARPLLPHGRTP------
-----------------------------------PVRKHTSYSVRTYESLDFQSGERSK
LQSHIRHCVRYMTETQRRCG-SKVQRYGG---------ADGKGWQLRTRLSFSIQRESQA
LNSSSSLRIFQTHKKETKSTKLIHESGCFLLKNKMT--------LFLLTSVFDNSIKTFG
VFESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGMSPDKLPGSLGHTHPQE-KDVWEEM-DANRNK-IKFGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDSSAGKEP----LLPALLRKPC-VPAGARTDHIWNYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDGNLRLGPWEENI-HLKKETSGVILALSRECPATAASEQYTDRLE
LQAGAGGQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQL-PEK-KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
MEHIGPDMLL---DTRECEKSQDLGPED---------LPD--HNRPAGRELESLPR-ETE
EKS-LLGS-DNEDEKLSKGQHYIEISS--LPGDL---ERDHSV-TTEPLDMTKTQTFSVM
PNQDRNHERMKLLSVGTSEISPEGIDPRAEGQ-IGQVATMQKSKISK-DDDIKSEDLPGL
QGDLSTFLHQEGKKEKIAPRNRELFNSVSESEHCPSSRKDMVRSSFVTRHSRIPVLAQEI
DSAFESSSPLSAKEKLLQKKAYQPDLLKLLVEKRQLKSFLGDLSSASDKLLEERLATVPA
PFSEEEVFTPFSRLAIDAPLSRSAEDSFLSPIISQSRKSKIPRPVSWINTDQVNSSASSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKAPPGK----SKSASKLS
R

------------------------------------------------------------
------------------MSGGGDQPDILSVGILVKER------------WK

PF07714 // ENSGT00920000148982_1_Domain_0 (113, 361)

VLRKIGGG
GFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPQEFNVFLDHISNLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LMSVFDNSMKTFG
VIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENVIPVGVSPEKVPGSPGHQRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGPGNGMLNAPSLGSPIRVRSETTQLDRDVPLVRKLRSIHSFELEKRMTLESKPDTD
KFLETCLEKKQKDLKL-AETPAAAVPPLSQKTSVPAPVTARTDHVWHYDEEYLPDASKPM
SANSPDHADGVISNGFVAVNLSSCRQEVDSKEWVIIDKERDLQDFRTNEALGHKMTGSPS
DEEPEVLQVLEEPLPEEQPREGGWAGNNVHAKNQTSGVEFVLDVECH-PAASEQLTDKLE
LLSGAAGQLLAATPTSPMEAQAEGALT---------------------------------
--------------------------------------------------PITIPRPSVA
STQSASESFHYGHPLERREQDGQSVEHTVELSSPKENLPGLVGTEDALPASASRPDLMLN
ISQE---VLDREGLVKGSVNVLDCDQK---------GLPE-HNRIQEEKELGNIPV-DEA
EEEGLPVVSEDAIEMLSKEQ------NSSLPGNSKSAEEEPLT-NTEAAQESKSRPVCLM
PNQDE---VLKSIAPKTAELSPSRLNNAHVNRQASKIATIQENGFHSDKEEVHSQDLKCH
QVALTTILQQENKKEKNAPRNGELFHCISENESSYRSKKDSVKSSFVFRQSRIPVLAQEI
DSMSDS-SSVSAKEKLLLKKAHQTDLVKLLMEKRQLKSFLGDLSSASDKSLEEKIAAAPV
PFSEDDVLASFSRLTLDSHFSKQNEDSSLSPSSPQSRKSKIPRPVSWATTDQVTSSSSAQ
FYPRPPPGKPPTRPGVEARLRRYRVLGSSSSDSDLISRLAQILQNGS--QRPRSSTQCKS
PGSPHSPKTPPKSPVIPRRSPSASPRSSSLPRTASSSPSRAGRSH-HDQRSSSPHFGRSK
SPPSHSGSSSSRRSCQQEHCCNKTGKNGLKGSGSSFHHSPSTKTSTGK----SKSTTKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 334)

WKVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKGTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDMLPNI---RESNKSQDLGPKE---------LPDN-NR-LVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--FPGDLVIVEKDHSA-TTEPLDVTKTQTFSVV
PNQDKNDEIMKLLTVGTSEISS-RDIDPHVEGQLGQAAEMQKNKISK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
PFCEEEALTPLSRLTVDSHLSRSTEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
---------------------------------AVEKDWGWG-------LWRNLRCLGHA
HQGECCTEGGI------------SSTTKTSSENGGCC-------FEKAAR

PF00069 // ENSGT00920000148982_1_Domain_0 (171, 332)

FIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 390)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYRVSTSGPQAFSSL

PF16208 // ENSGT00920000148982_1_Domain_1 (390, 486)

SYMSGP-GACISSLSFS-------RVGSSSF
WSGLGGGCGRASG--MGGITAIT-VSQSLLSPL-------------------NLEMNPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VYS

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 666)

QEKEQIKSL-NKFASFIDKVRFLEQQNKMLETKWSLLQQ--QKM--------
-----------LET-------LGQEKLKLEAELGN-----------------MQGLVEDF
KNKHEDEINKRTEMENEFVLIEKAVDEAYMNKEELTD--K----I-----SFLRQLC---
-EEEI

ENSGT00920000148982_1_Linker_2_3 (666, 737)

G----------SCSPRSWI--RLWCS--------------AS-WTWTASSRRS--
RRWLGSMGMTCMGSRL

PF00038 // ENSGT00920000148982_1_Domain_3 (737, 840)

RLRLAVKNANAKLSELEAALQRAKQDMAQQLLV-----------
-------------YQELMN-----------------VKLALDVEIATY--RKLPEGEESR
LESGMQNMSIHMKITSSCVG-GQSLAYGG---------LTSPGLSYSLGSSFVCGVGSSS
FSRISSFRVV-VVKNETRDGKL------------------------LLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPMEPTVELYSPRENFSGLAVTEGEPPSGGSRTDLGLQ
IDHIGHDVLP---NIRESNKSQDLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCMEISS--LPGDLVIVEKDHSA-TTEPLHVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISPRDIDPHVEGQ-IGQVAEIQKNKVSK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSSVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKTPPGK----TKPASKLS
R

MGLANRRHGLGTCSPISTRGGESCKTGKIKCLLKETHSW---------LRRELGTRLNGN
HPWELDACVAVLPHRCFAMSGGGEQPDILSVGILVKER------------WKV-------
--------------------------------------------

PF00069 // ENSGT00920000148982_1_Domain_0 (165, 332)

KDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPSEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESEPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHARPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGHINGIPNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCMEKMQKDSSAGKES----VLPALPHKPC-VPVGSRTEHIWHYDEEYLPEASKPA
SANTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEVLGHKTTGSPS
DEEPEVLQVLEGSPQDEKIQVGPWTDNH-HLK-ESSGVVLALSAECPATAASEQYTDRLD
LQAGAASQFLTVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGPQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGELPSGGSRMDLGLQ
IDHIGHDMLPNM---RDGDTSQDLGPKD---------LCDH-NR-LVVKEFENLPG-ETE
EKSILLGS-DNEDEKLSKGQHCVEISH----PDLVTTERDQSA-TTEPLDVSKTQNFSVV
PNQDKKHEIMKLLTVGTSEIS--QVIDPHAEGQIGQVAVMQKNKLFK-DADIKSEDLPGH
QGDLSTFLHQEGKREKVVPRNGELYHCVPENEHGTPTRKDMLRSSFVTRHSRIPVLAQEI
DSTFESSSAVSAKEKLLQKKAYQPELVKLLVEKRQFKSFLGDLSSASDKLIEEKLAAAPV
PFSEEEVFTPFSRLAVDSHLSRSAEDGFLSPIISQSRKSKIPRPVSWVSTDQVNSSASPQ
FLPRPPPGKPPIRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTPQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGPKGSGSLHHHSASSKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------------------------------------------------
--------------------------------M

PF07714 // ENSGT00920000148982_1_Domain_0 (154, 336)

EVAVLKK-LQGKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRTVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LISVFDNSIKTFG
VLESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLVQPRPQE-KDVWEEL-DANRNK-IKLGICKAATEE
ENSHGQANGMLNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMHKDSSAGKES----TLPAPLYKPC-VPAVSRTDRIWHYDEEYIPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPHNEKLRS--FAE-N-DLKKETSGVVLVLSGECPATVPSEQYTDRLE
LQAGAASQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIARPSVA
STQSISGSFHYGQQ-PEK-KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
LDHIGHDILPREVHIRGCDKSQDLGQKD---------LPD--RNRLVMREFESHPG-ETE
EKSNLLGP-DNENEKLNKGQSCIVISP--IPGDLVTMERDRST-ATEPFDVTKTQTFSVV
PNQDKNHEIMKLLPVGTSEISPRVIDPHVERQ-MGHVAAVQKSKIPK-DNDIKSDDLPGH
QGDLTTFLHQEGKREKITPRNGELFHCVSENEHCPPSRKDMVRSSFVTRHSRIPVLAQEI
DSAFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKLLEEKLATVPA
PFSEEEIFTPFSRLAVDSHLSRPAEDSFLSPAISQSRKSKIPRPVSWVNTDQVSSSTSSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPWTTTQCKS
PGSPHNSKTPPKSPVVSRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSSSLHHHSASTKTAPGK----SKTASKLS
R

------------------------------------------------------------
-------------------------------MESLSKDWGWG-------LWRNLRCLGHA
HQGKCCTEGGI------------SSTTKTSSENGSCW-------

PF00069 // ENSGT00920000148982_1_Domain_0 (165, 332)

KDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTMSTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 392)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYKVSTSGPQAFNSLSY

PF16208 // ENSGT00920000148982_1_Domain_1 (392, 486)

TSGP-GACISSLSFF-------RMGSSSF
WGGLSAEYGGAGGA-SGGITAVT-VNQSLLSPL-------------------NLEVDLNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VRT

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 680)

QEEKQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLVQQ--QKMARSNMDNM
FESYINSLRWQR-------------RLWLEAELGS-----------------MHRLVEDF
RNKYEDEISMCTEMENEFVLINGGF------------SPE----GLTAEISFFRQLY---
-EEEIR----------SCS

ENSGT00920000148982_1_Linker_2_3 (680, 732)

TRSRI--HLWCCSWTTA---------AS-WTWAASSLRSRG
TGFPG---GRH

PF00038 // ENSGT00920000148982_1_Domain_3 (732, 839)

ADTKQRGELAIKDADAKLSELEAALQLASQDMAQQLHE-----------
-------------YQELMK-----------------VKLALDIKIATY--RKLLEGEESW
LESGMQNMSIHMKTTSSYAG-GQSL-----------------------------------
----------------------------------------------LLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAVG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAASRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHTGRDMLP---NIRESNKSQDLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKDHSA-TTEPLDVTKTQTFSVV
PNQDKNNEIMKLLTVGTSEISSRDIDPHVEGQ-IGQVAEMQKNKISK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSPVSAKEKLLQKKAYQPDLVKLLVERRQFKSFLGDLSSASDKLLEEKLATVPA
PFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 270)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQARGTFTISTTLRLGRQILESIESIHSVGFLHRDIK------
-----------------------------PPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSVFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGMDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGVPVPVSPDRLPGSPGHPRPQE-RDVWEEM-DANRNK-IKLGLCKAATEE
ENSHGHANGMLNAPSLGSPVRVRSEITQPDRDAPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETWYKIGFLPI----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------WK

PF07714 // ENSGT00920000148982_1_Domain_0 (113, 335)

VLRKIGGG
GFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPTEFSVFLDHISSLDYFT
KPDYQMSYKCVALKSISLNFHLPDSLKFLLYRFGLGSNQ-QPSKISNSGQGQSRGQ---F
MSRRRIA--------RGSRTWAQAESPTKIVW-RATREKNRERKRQQLQTVFGVLLEF-S
QFTRLLSV-SRTRLKCKWEM-FGKMSKNT-IKYN----VILW------------------
---FSNSM-WGLLG--------------Y-SIIKI--QAD-QNSGALIPNKT--------
L-RSQVTNCSCY-FRNITLLA--------KDKVGFQT-SEYDTAI-DFILHIL-SFFLAL
-SQELGFL-SPRFRFS-LGFLTY-THTDFW-LFRVLN-LSQDCYL-LSASWSDIKK-ISR
-NF-----------------------EIIE-NN--------SLSLILLK-NDV-------
--------ALIAQME-ILNKKLSRIQIEGE--LRWQLSSRNLLNLLPTDHYKVSQKDRNQ
NRTSKG--TLPQD-AGLKVGSSLGSRTWSLARDRAEHSQGSRGWKDSLRA----------
--------------------------------KSFKVGYTKNVILPLLTNVFDNSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSVGHPRPQE-KDVWEEM-DVNRNK-IKLGICKAATEE
ENSHGPANGILNAPSLGSPIRVRSEITQPERDVPLVRKLRSIHSFELERRLTLESKPDTD
KFLETCLEKMQKDSNVEKESV---LPASLLHKPS-APPVIRTDHIWHYDEEYLPDASKPA
-ANSPEQADGAGSNG-IAVNLSSCQQEVDSKDWVIVDKERDLHDFRTNGALGHK-TGSPS
DEEPEVLQILEESPQE-QQRLGPWVEDG-HPKNGVPGVVLALSVACPATEASEQYADRLE
LQAGAAGQFLAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------PVTIPRPSVA
STQSTSGSFHYGQPLEK--KDPQPLEHTVELYSPRENVSGVVGTEGELPSGASRTDWVLP
LDHLGQDTAPREGLTRECVKSQDLVQKE---------PPDRSNVKVATKEFETLPV-GAE
EKSVVLGS-DNEEEKLGKGQCFIEISD--FPGDLEREHS----PTKEPLEEFKTRTFCLV
PNQDTNHEIMKLLAGATSELSPAQVIHPHGEGQISQVVVQKNKLQKE-EDVSKGEGVPSH
QRDLSVFLHQEGKKEKISPRNGELFHCLSEKEHSP-SRKDVIRSSFITRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKSLEEKLAAVPV
PFPEDEVFTPFSRLAIDPHLGRSAEDSFLAPLSSQARKSKIPRPVTWTNTDQVSNSASAQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSSTQCKS
PASPHSPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCCLKPSKNGMKGSGSLYHHSASPKTPPGK----SKSASKLS
R

------------------------------------------------------------
-------------------------------MESVEEDWGWG-------L

PF00069 // ENSGT00920000148982_1_Domain_2 (111, 951)

WRNIRCLGHA
YQGKCCTESGI------------SSTTKASSENGGCCIKKTTRRKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLRSRGSPGAGE-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGQANGIMNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKESSAGKES----LLPALLHKPC-VPAVSRADHVWHYDEEYLPDASKPA
SANTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVLVDKEQDLRDFRTNEALGHKTNGSPS
DEEPEVLQVLEESPQDEKFRLGPWAEND-PLKKHTSGVGLTLSGECPAIAASEQYTDRLE
LQAGTTSQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSAA
STQSTSGSFHYGQLMPEK-KDLQPMEPTVELYSPRENFSGMVGTEGEPPSAGSRTDLGVQ
IDHIGHDVLP---NIRESDKCQDPGSKD---------FLD--HNKRALKEFENLPR-ETE
EKSILLGS-ENEDEKLSKGRQCIEISS--LPGDLVTLERDHSA-TSEPLDVTKTQTFSVV
PNQDKNHEIMKLLAVETSEVSPRLTDSHVEGQ----VAAIQKSKLPK-DDESKSEDLPGY
QGDLSTFLHQEGKKEKVAPTNGELFHCVSESEHCPPSRKDMVRSSLVTRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDFSSASDKLLEERLAA--A
SFSEEEVLTPFSRLAVDSHLSRSAEENFLSPIISQSRKSKIPRPVSWVNTEQVNSSTSSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKP----QCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-N-KNGLKGTGSLHHHSASTKAPPGK----SKSASKLS
R

------------------------------------------------------------
---------------------------------AVEKDWGWG-------LWRNLRCLGHA
HQGKCCTEGGI------------SSTTKTSSENGSCC-------FEKAA

PF00069 // ENSGT00920000148982_1_Domain_0 (170, 332)

RFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 391)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYKVSTSGPQAFNSLS

PF16208 // ENSGT00920000148982_1_Domain_1 (391, 486)

YTSGP-GACISSSSFS-------RMGSSSF
RGGLGAGYGG---A-SRGITTVT-VNQSLLSPL-------------------NLEVDPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VRT

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 678)

QEEKQIKTLNNKFFSFIDKVRFLEQQNKMHETKWSLVQK--QKMAWSNMDNM
FESYINNLKWQLET-------LGQEKLKLEAELGN-----------------MHGLVEDF
RNKYEVEISKCTEMENECVLNKEDVDEAYMNKMELESSLK----GLTAKISFLRQLY---
-EEEIG----------S

ENSGT00920000148982_1_Linker_2_3 (678, 732)

CSPRSRI--HLWCCSWTTA---------AS-STWTASFLRSRP
EGFPG---GRH

PF00038 // ENSGT00920000148982_1_Domain_3 (732, 839)

ADTEQRGELAIKDANAKLSELEAALQLASQDMARQLRE-----------
-------------YQELMN-----------------VKLALDIKIAPY--RKLLEGEESW
LESGMQNMSIHMKTTSSYAG-GQSLAYGD---------LTSPGLSYGLGSSFGSGMGSSS
FSHTSSSRAVVVKKIETRDGKLVSESSDVLPNLRITATVSPCSDGKLLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGIYKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHCGQQ-PEK-KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDMLP---NIRESNKSQDLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHCIEISS--LPGDLVIVEKVHSA-TTEPLDVTKTQTFSVV
PNQDKNNEITKLLTVGTSEISSRDIDPHVEGQ-IGQVAEMQKNKISK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
PFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSSSLHHHSASTKTPQGK----SKPASKLS
R

MGLANRRHGLGTCSPISTRGGENCKTGKIKCLLKETHSW---------LRREIGNRLNGI
HPWELDACVAVLPHQGFAMSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DINKNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCMEKMQKDSSAGKEP----VLPALPHKPC-VPVVTRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEVLGHKTTGSPS
DEEPEVLQVLEGSPQDEKIQVGPWTDNH-HLKKESSGVVLALSAECPATAASELYTDRLD
LQAGAASQFITVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGPQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGELASGGSRVDLGLQ
IDHTGHDMLPNM---RDGDTSQDLGPKD---------PPDH-NR-LAVKEFEHLPG-ETE
ERSLLLGS-ENEDERLSKGQHCIEVS---SPGELVTAERAQLA-ATEPLHVSETQNCSVL
PNQDKTHEIMKLLAVGTSEISP-QAIDPHAEGQIGQMAAMQKNKLFK-DDGIQSESLPGQ
QGDLSAFLHQEGKREKVVPRNGELYHCVSENEHGPPTRKDMLRSSFVTRHSRIPVLAQEI
DSTFESSSAISAKEKLLQKKAYQPEIVKLLVEKRQFKSFLGDLSSASDKLIEEKLAAAPV
PFSEEEVFAPFSRLAADSHLSRSVEDSFLSPIISQARKSKIPRPVSWVSTDQINGSASPQ
FLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGPKGSGSLHHHSTSSKTPPGK----SKPASKLS
R

-------------------------------MESVEEDWGW-------------------
------------------------------------GL------------

PF00069 // ENSGT00920000148982_1_Domain_2 (111, 1025)

WRNLRCLGHA
YQGKCCPEGGIS------------STTKASSQNGGCCIEKTT-RKDHVCKFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKXXXXXXXXXXXXXXXXXXXXXX---------------
--XXXX------------------------------------------------------
------------------------------------------------------------
---------------------------------------XX-------------------
------------------------------------------------------------
------------------------------------------------X-----------
--------------------XXX-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------XX----------
--------------------------------XXXXXXXXVHMQNKLLTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEI-DVNRNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSXXXXXXXXXXXXXXXX
XXXXXXLEKMQKDSSAGKES----VLPALLHKPC-VPAGAHTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQD-DSKEWVIVDKEQDLQDFRANEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLQFGPWAENI-HLKKETSGVILALSGECPATAASEQYTDRLE
LQAGSASQFIAATPTSPMVTQAERPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGHQPEK--KDLHPVEPTVELYSPRENFSGLVVTEGEPPSGGSRIDLGLQ
IDHIGHDMLPNI---RECDTSQDLGPKD---------LPDHN--RLSVREFESLPR-ETE
EKSILLGS-DNEDAKLSKGQHYIEIAP--LPGDLVTVERDHSA-TTEPLDMTKSQTFSVV
PNQDKNHEIMKLLAVGTSEISP-RVIDPHVEGQIGQVAAMQKSKISK-DDGIKSEDLPGH
QGDLPTFLHQEGKKEKIVPRNGELYHCVSESEHCPPPRKDVVRSSFITRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKLLEERLATVPA
PFSEEEVFTPFSRLAVDSPLSRSAEDSFLSPIISQCRKSKIPRPVSWVNTDQVNSSTSSQ
FLPRPPPGKPPMRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HAQRSSSPHLGRSK
SPNSGS---SSRRSLQ-QECQ--PSKNALKGSGSLHHHSASTKAPPGK----SKSASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLAGSLGQPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLEACLEKRQKDTSAGKE----SILPALLHKPC-VPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQGDGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEVIGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQ
IDHIGHDMLPNF---RESNLSQDLGPKE---------LPDH-NR-LVVGESENLPG-ENE
EKSILLES-DNEDEKLSRGQHCVELSS--LPDLL-MVEKDHSA-TTEPLDVTKTQTFSLV
PNQDKNKEVMKLLTVGTSEISP-RDTDSHVEGQIGQVAEMQKSKIPK-DDDIMSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEI
DSTLESSFPVSAKEKLLQKKAYQPDLVKLLMEKRQFKSFLGDLSSASDKLLEEKLATVPA
SFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKSRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSANTKTAPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 334)

WKVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLESKPDTD
KFLETCLEKMQKDSSAGKES----VLPSLLHKPC-VPAMSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGASNGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLLLGPWAESN-HLQKEPSGVVLALSGECPATAASEQYTDRLE
LQAGTAGQFAAVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQQEK--KDLQPVEPTVELYSPKENFSGLVVTEGEPPSGGSRTDLGLQ
IDHTGHDLLANI---RECNKSQDLGPND---------HPDH-NR-LALRELESLPR-ETE
EKSNLLRS-DNEDEKLSKGQHYIEIAS--LPGDLVTVERDHSA-TTEPLDVAKTHTFSVV
PNQDKNHEIMKLLEVETSEVSS-QVIDPHVEGQIGQVAAMQKGKPSK-DDDVRSADLPGQ
QGDLSTFLHQEGKREKMAPRNGELFHCVSESEHCPPSRKDVIRSSFVTRHSRIPVLAQEI
DSTFESSSAVSAKEKLLQKKAYQPDLVRLLVEKRQLKSFLGDLSSASDKLLEERLATVPT
PFSEEEVFAPFSRLAIDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVSSATSAQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRGTPQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAARPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSSSLHHHSASTKAPPGK----SKSATKLS
R

------------------------------------------------------------
-------------------------------MESLSKDWGWG-------LWRNLRCLGHA
HQGECCTEGGI------------SSTTKTSSENGGCW-------K

PF00069 // ENSGT00920000148982_1_Domain_0 (166, 332)

DHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE

ENSGT00920000148982_1_Linker_0_1 (332, 388)

RYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQVTIFVSSK-SYKVSTSGPQAFS

PF16208 // ENSGT00920000148982_1_Domain_1 (388, 486)

SLSYTSGP-GACISSSSFS-------RVGSSSF
WSGLGGGCGRASG--MGGITTVT-VNQSLLSPL-------------------NLEMNPNI
---QA

ENSGT00920000148982_1_Linker_1_2 (486, 489)

VYS

PF00038 // ENSGT00920000148982_1_Domain_2 (489, 677)

QEKEQIKSL-NKFASFIDKVRFLEQQNKMLETKWSLLQQ--QNMARRNMNDM
FESYINNLRRQLET-------LGQEKLKLEAELGN-----------------MQGLVEDF
KNKYEDEINKRTELENEFVLIEKAVDEAYMNK-------E----GLTDKISFLRQLC---
-EEEIG----------

ENSGT00920000148982_1_Linker_2_3 (677, 737)

SCSPRSWT--RLWCS--------------AS-WTWAASSRRSSC
RRWLGSMGMTCMGSRL

PF00038 // ENSGT00920000148982_1_Domain_3 (737, 840)

RLRLAVKNANAKLSELEAALQQAKQDMAQQLLV-----------
-------------YQELMN-----------------VKLALDVEIATY--RKLPEGEESR
LESGMQNMSIHMKITSSYVG-GQSLAYGV---------LTSPGLSYSLGSSFVCGVGSSS
FSHISSFRVV-VVKNETRDGKLVSESSNVLPNLRITATVSPCSDGKLLTSVFDNSIKTFG
VIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDTSAGKES----ILPALLHKPC-VPAVSRTDHIWHYDEEYLPDVSKPA
SANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPS
DEEPEVLQVLEASPQDEKLQLGPWAEND-HLKKETSGVVLALSAEGPPTAASEQYTDRLE
LQPGAASQFIAATPTSLMEAQAEGPLT---------------------------------
--------------------------------------------------AIKIPRPSVA
STQSTSGSFHYGQQ-PEK-KDLQPMEPTVELYFSKGKLLWLVEEAE--------------
---------------QIWVTNLRLGPKE---------LPD--HNRLVVREFENLPG-ETE
EKSILLES-DNEDEKLSRGQHYLVIVE--KDTQLL-------------------------
-------------------------------------------------LNLFIEDLPGH
QGDTLYFFA---------------------------------------PRGRIPVLAQEI
DQ-LESSSSVSAKEEAPPRRKLISQPSQASGGKKTIQSFLGDLPSASDKLLEEKLATVPA
TFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQSIAQLHLS
SFLATTRKATPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
-------------------------------MESIEEDWGWG-------L

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 368)

WRNLRCLGHA
YQGKCCTEGGI------------SSTTKTSSENGSCCIEKTT-RKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPW-KIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQLHIXXXXX-XXXXXXXXXXXXX---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------X----X-------------------------------------------X---
---------------------------------------------XX-XX----------
-XXXX-------X-----------------------------------------------
------------------------------------X----------X------------
------------------------------------------------------------
-----------------------------------------------XXXX---------
-------------------XXXXXXXXXXXXXXXXXXXX-IANATPIPGDLLRENTDECS
DQ----LDENGHPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DANRNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLVLEPKPDTD
KFLETCLEKMQKDSSEGKES----VLPALLHKPC-VPAVSRTDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLRLGPWAEND-HLKKETSGVILAVSGKCPATAASEQYADRLE
LQAGAASQFIAVTPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRRSVA
STQSTSGSFHYGQL-PEK-KDLHPMEPTVELYSHMESFSGLVVTEREPPSGGNRTDFGLQ
IDHIGHDMLP---SIRECDSSQDLGPKD---------LPD--HNRLAVREFEGLPR-ETE
EKSMLVGS-DNEDEKLSKGQPYIEISP--LPGDLVTVERDHSA-TTEPLDVTKTQTFSVV
PNQDKTHEIVKLLAVGTSAISPRVIDQHVEGQ-IGQVAAMQKGKISK-EDDIKSEDLLSH
QGDLSTFLHQEGKREKIAPRNGELFHSVSESEHCPPSRKDVVRSSFVTRHSRIPVLAQEI
DSTFESSCPVSAKEKLLQKKAYQPDLVKLLVEKRQLKSFLGDLSSASDKLLEERLSTIPA
PFSEEEVFTPFSRLAVDSHLSRSAEDSFLTPIISQSRKSKIPRPVSWINTDQINSSTSSQ
FLPRPPPGKPPMRPGVEARLRRYRVLGSSSSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSSSLHHHSASTKAPPGK----SKSASKLS
R

------------------------------------------------------------
-------------------------------MESVEEDWGWG-------

PF00069 // ENSGT00920000148982_1_Domain_2 (110, 951)

LWRN-RCLGHA
HQGKCCXXXXXXXXXXXX------------XXXXXXXXXXXXXWKDHVCRFIGC--NDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQXXXXXX-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------XXXXXLLTSVFDNSIKTVG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGISPDKLPGSLGHPRPQE-KDVWEEM-DANRNR-IKLGICKATTEE
ENSHGQGNGMLNAPSLGSPIRVRSEITQPDRDLPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLEACLEKMQKDSSAGKQS----TLPAQLHKPC-VPAVSRMDHIWHYDEEYLPDASKPA
SANTPEQADGAGSNGFIAVNLSSCKQEVDSKEWVIVDKEHDLRDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQGEKLGLGPWEEND-HLKKETSGVLLALLGECPATAASEHHTDRLG
LQAGIVSPPIAATSTSPLEAQAEXXXX---------------------------------
--------------------------------------------------XVTIPRLSEA
SRQANSGRMHFTQGK-EM-EHRERGGPSTERS-PPGNRHG-KDTEGE-PASRSRTDLGLQ
LDHIGHDMLPKEVHIRECDKSQDLGQRD---------LLD--HSRLVVREFESLPG-ETE
EKS-ILES-DNENEKLSKGQCCIEISP--VPGDLVTTERDHSA-TTEPLDITRTQTFSVV
PNQDKNHEIMRLLATGTSEISPRVIDPHVEGQ-ISQVAAMQKWKLSK-DDGIKSEDLPGH
QGDLSTFLHQEGKRERIAPKNGELFHCVSENEHCPPSRKDVVRPSFVSRHSRIPVLAQEI
DSAFESSSPVSAKEKLRQKIPPQPDLL--LLAEKQLHSFLGDLS-ASDKLLGGKLAA--T
SFSEEEVFTPFSRLAVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWANTDQVSSSASSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSNTQSKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSLHHHSASIKTPPGK----NKSASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQARGTFTVSTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDKSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGMPVGMSPDRLPGSPGHPRPQE-KDVWEEM-DVNKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSETTQPDRDAPLLRKLRSIHSFELEKRLTLEPKPDTE
KFLETCLEKMHKDSSAGKGA----VMPALLQKPC-PSAASRTDHVWHYDEEYLPDASKHA
SAHTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEALGHKTTGSPS
DEEPEVLQVLEESPQDEKLQLGPWAGSG-HLKKEPSDVVLALSVECPATAPAEQDPDRLE
LQAGVASQFIAATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQH-LEK-KDLQPLEPTVELFSPRENFSGLAVTEGE----------GLQ
VDHVGQDTLP---HVQESDRSQDLGPKD---------LPD--DTGLVGREFENFPV-ETE
EK-IIPGA-DNEDEKLSREQYCVE-LS--LQGDLGTEEKDHSA-TTEPLDGTKTQTFSVV
PNQDRNHEIVRFLAAGTSELSPTVIDPPVEGQ-HGQVAAVQKSRLPK-GDDIQMEALPEH
HEGLSALLCQEDKREKSAPRNGELIDCIAESECAPPARKDVVRSSLVTRHSRIPVLAQEI
ESAFEASSPVSAKEKLLQKKAHQPDLVRLLVGKRQLRSLLGDLSSASNKLLEDKLASVPV
PFSEEDVLVPFSKLAVDAPLSRSAEDNFLSPISSQSRKSKIPRPVSWVSTDQVSSSLSSQ
FLPRPPPGKPPARPGVEARLRRYRVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTPCKS
PGPPHNPKTPPKSPVVPRRSPSASPRSSPLPRTSSSSPSRAGRPH-HEQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-RGSPKGSGSLHHHPASSKAPLGK----SKPASKLS
R

-----------------------------------EKDWGW-------------------
------------------------------------GL------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 359)

WRNLRCLGHA
HQGKCGTESGIGSTTQ-----------TSSENGSCCFEETTR-RKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-----------------
---XXXXXXXXXXX--------------XXXXXXX--XXXXXXXXXXXXXXX--------
XXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-XX-----------------------XXXX-XXX-------XXXXXXXXXXXX-------
--------XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------
--------------------------------XXXXXXXXXXXXXXLLASVFDNSIKTYG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGLPVGVSPDKLPGSLGHPHPQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLEKMQKDSSAGKES----ILPALLHKPC-VPAMSRTDHVWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLTTCKQEVDSKEWVIVXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------
--------------------------------------------------XFTIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPLEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLALQ
IDHIGHDMLPNI---RESDKSQDLRLKD---------LPNH---KMVVREFENPPG-ETE
EKSILLGS-DNDDEKLSKEQHCIEITP--FPGDLTAERE-H-SATTEPLDVTKTQTFSVV
PNQDKNHEIMKLLSIGTSEISP-RVIDPHVEGQIGQVTTMQKSKLSK-DDAIKSEDLPGH
QGDLSTFLHQEGKREKIAPRNGELFHCVSENEHGPPTRKDVVRSSFVTRHSRIPVLAQEI
DSTFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPA
SFSEEEVFTPFSRLAVESHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQLSSSNSSQ
FLPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRTGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSSNLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGILVKER------------W

PF00069 // ENSGT00920000148982_1_Domain_0 (112, 332)

KVLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLEHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKAFG
VIESDPFDWEKTGTDGSLTTTTTSATPQLHTRLTPAAIG-IANATPIPGDMLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSLGHPRPQE-KDVWEEM-DTNRNK-IKLGICKAATEE
ENSHGQANGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLALEPKPDTD
KFLETCLEKMQKNPSAGKES----TLPALLHKPC-VPAVSRADHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFVAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEALGPKTTGSPS
DEEPEVLQVLEESPQDDKFQLGPWAEND-RLKKETSGVVFVLSGECPATAASEQYIDRLE
LQAGAASQFITATPTSPMEAQAEGPLT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQ-PEK-KDPHTIEPTVELYSPRENFSGLVVIEGEPPSGGSRTDLGLQ
IDHIGHDMLP---NIREYDRSQDLGPKD---------LPD--HNRLAMREFEDLPR-ELE
EKSIVVGS-DSKEEKLSKRQHYIEISP--LPGDLVTMERDHSA-TTEPLDVTKTQTFSVV
PNQDRNQEIMTLVAVGPSEVSPRVIDPYVEEQ-IGQVAAMQKSKISK-EDDIKGEDLPNH
SGDLSTFLHQEGKREKIAPRNGELFNPVSESEHCPPSRKDVVRSSFVTRHSRIPVLAQEI
DSTFDSSSPVSAKEKLLQKKACQPDLVKLLVEKRQLRSLLGDLSSASDKLLEERLTAVPA
PFSEEEVFTPFSRLAADSHLSRSAEDSFLAPIISQSRKSKIPRPVSWVNTDQVNSSAPSQ
FLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGTPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCKP-S-KNGLKGSGSFHHHSASAKAPPGK----SKSASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILSVGVLVKER------------

PF00069 // ENSGT00920000148982_1_Domain_0 (111, 340)

WKVSKKIGGG
GFGEIYDAMDLLTRESVALKVESALQPKQVLKMEVAVLKKLQ-GKDHICKFVGCGRNDRF
NYVVMQLQGRNLADLRRSQSKGTFSVSTTLRLGKQILESIESIHSVGFLHRDIKPSNFAM
GRFSSTCRICYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPQEFNTFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LMSVFDNSMKIFG
VAESDLFDWEKTGIDGSLITVTNSTTPQIHTRLTPAMGGKIANATPIPGDLMRENTDEVF
PDEQLSDGENGIPIGISPEKLPEFPGH-RVQE-KDVWEEM-DANRNR-IKLPVQKAATEE
ENSHGPINGMLNAPSLGSPIRVRSETTQPDRDVPLVRKLRTIHSFELEKRLTLESKPDTD
KFLEICMEKKKRELNAGKES----IVATSQKASK-PAASSGPEHVWHYDEEYLPEVSKPG
SGGSPEQGDGGVSNGYVAVNLSSCQQECDSKEWVIVDKERDLQDFRTNGVVGHKTTGSPS
DEEPEVLQVLEESPQDDKPG-------A-HTKNTTIGAPLDLGVECGGTAASEQFTDQLE
FPVGTSGHLLAVTPSSLMDAQAEGAFT---------------------------------
--------------------------------------------------PVTIPRPSMA
STQSASESFHYGQQMDKKERDTRLLEQNVELLSPKENLAASIAANDALTFSGSKTDIVLK
LDHDL----------EACDKGGHAGEGAGIHDCSQTDLLEQFMKRKGERELAGLFE-ED-
-KQLPVVC-ENAFELQTKGPCLTVLGNSEP---L----FDEPQ-VATELEELRPFTSCPL
PNQDAKQELLKQSAAETSDVSLSRSTDPFAHRLESQV-PVQENGFQD---DGDIDRGEDQ
QVNLDNFTHQKMKEEQNVQKNGDIFHSISENETSHQSKKELVRSPFAARQSRIPVLAQDI
DSSSE-SSPVSAKEKLLLKKAHQTDLVKLLVGRKHLRSFLGDLSSASEKSLKEKGVTGPI
PLSE-DVLSSISKLTLDTHLHNQVEESYLSPNNPLTRKSKIPRPVSWTAMDPVNNSNSAQ
FFPRPPPGRPPTRPGVEARLRRYKVLGSSSSDSELISRLAQILQNGS--QKPRSSSQCKS
PGSPHSPKTPPKSPVIPRRSPSASPRSSSLPRTASSSSSRSGRPH-HDQRSSSPHLGRSK
SPPSLSGSSSSRRSCQQEHCYNKSNKNGLKGSSGSCHHSSNVKPPTGK----SKSASKLS
R

-------------------------------MLLTLANWRMQSSDSPILRMAPQIVLNGN
HPWELDACVAVLPHQYIAMSGGGEQPDILSVGILVKER------------WK

PF07714 // ENSGT00920000148982_1_Domain_0 (113, 335)

VLRKIGGG
GFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFVGCGRNDRF
NYVVMQLQGRNLADLRRSQVRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRSPRAMAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LTSVFDNSIKTFG
VIESDPFDWEKTGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPDKLPGSMGHPRHQE-KDVWEEM-DANKNK-IKLGICKAATEE
ENSHGQPNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTD
KFLETCLERMQKDSSAGKE----SLLPAVLHKPC-IAAVPRGDHIWHYDEEYLPDASKPA
SANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEKDLQDFRTNEPVGHKTTGSPS
DEEPEVLQVVEDSPQDEKLRLGPWAENA-HLQKETSGVVLALSTERPATATAEQYTDRLE
LQAGAAGQFIAATPTSPMEAQAEGPIT---------------------------------
--------------------------------------------------AITIPRPSVA
STQSTSGSFHYGQQPEK--KDLQPMEPTVDLYSPKENFSGLVVTEGEPPSGGSRTDLGIQ
IDHIGHDLLPNI---RESDGSQDLGPKD---------L-DQ-NR-LNVRESENLPG-ETE
EKSI-LGS-DNEDEKLSKGQHCIEISS--IPGDLATVERDHSA-TTEPLDVTKTQTFSVV
PNQDTNHELMKLLAIGTSETSP-TVIDPHDEGQIGQVATGHKNKIGK-DDDIKSEDLMVH
QEDLSTFLHQDGKREKIAPRNGELFHCVSENEHGPSARKDVVRSSFVTRHSRIPVLAQEI
DSSFESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASEKLLEEKLATVPA
PFSEEEVFTPFPRLAVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQ
FLPRPPPGKPPSRPGVEARLRRYRVLGSSNSDSDLFSRLAQILQNGS--QKPRSTTQCKS
PGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCK--PSKNGLKGSGSLHHHSASTKTPPGK----SKPASKLS
R

------------------------------------------------------------
------------------MSGGGEQPDILTVGILVKER------------

PF00069 // ENSGT00920000148982_1_Domain_2 (111, 952)

WKVLRKIGGG
GFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ-GKDHVCRFIGCGRNDRF
NYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM
GRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDL
WSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPQEFNIFLDHICNLDYFT
KPDYQL------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LMSVFDNSMKTFG
VIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIG-IANATPIPGDLLRENTDEVF
PDEQLSDGENGIPVGVSPEKLPGSPGHQRSQE-KDVWEEM-DANRNK-VKLGICKAATEE
ENSQGPVNGMLNAPSLGSPVRVRSETTQLDRDVPLVRKLRSIHSFELEKRLTLESKPDTD
KFLENCLEKRQKDLNAAAETAVAAVPPLPQKSLIPAPVAARMDHVWHYDEEYLPDASKPG
SAGSPEQVDGVVGNGFVAVNLSSCRQEIDSKEWVIIDKERDLQDFRTNEVLGHKTTGSPS
DEEPEVLQVLEESPPDEQPREGGWAGNSVHAKNQTSGVEFILAMESH-PASSEQLTDKLE
LLTGAAGQLLAATPTSPMEAQAEGALT---------------------------------
--------------------------------------------------PVTIPRPSVA
STQSASESFHYGHQLDKRERDAQSMEQTVELLSPRETLPCLVVTGDT-TVSGSRPDMILR
ISQE---VLEREEHVKECTSVLSNGQK---------DLPEKHSGRQEEKELEKLPV-ET-
EEELLPVVSEDAAVMLSKEQ------N-SLPGSSKSADEEPLT-NTDAAEESKPRPVCLV
PNQDE---FLKSTAPETPEFSPSRRINPYANRQASKIAPVQENGFHSIKEEVHVQDLQCH
QVALTTFLHQEDKKEKNAPRNGELFHCISANENSHRSKKDLVKSPFVFRQSRIPVLAQEI
DSTSESSSPVSAKEKLLLKKAHQTDLVRLLVEKRQLKSFLGDLSSASDKSLEEKMAAAPV
PFSEDDVLSSISKLALDSHFSKQTEDSSLSPSSPQSRKSKIPRPVSWATTDQVNGSSSTH
FLPRPPPGRPPTRPGVEARLRRYRVLGSSSSDSDLISRLAQILQNGS--QRPRSSTQCKS
PGSPHSPKTPPKSPVNPRRSPSASPRSSSLPRTASSSPSRAGRTH-HDQRSSSPHLGRSK
SPPSHSGSSSSRRSCQQEHCYNKPSKNGLKGSGSSLYHSPNTKTPTGK----SKSASKLS
R