Query Results 

MGRNQGKASQRLARPGRPASREQESGSASADS-APSRERRYDRGQADKARPAAERATAGS
QGTAGGRKKPTAEENGGCRRPEAGSPPEAQERQGSARRQGRGPRDGR------GGCLEEG
SLSRE-ER----GGHRRRKGKGRESSARRDHREPRSLYGDTSGGDGGSYCPDSETREAQE
SGSQRGGARELRPTLEPTDTGSEGTKTEPESALAS----S-SDCLDSDGLRAYPRSRKRS
LRAGPPGASEHSGGDSDSSLLGAGPEPGPRGAT--ASRT--------------------F
EGSSRYPRDTGPAQDASDNRAQ-----RGAERETGEGSTARAPRRQVGKALGPVPLAAGV
SEAGAAAGA-----GPEEPAPLASLLAVRRLLARPPPGAASQVVGPRRPGLQERLQRVAR
TLGLLSWLRLRLRLKLRPPDGEGLRARPPASEGRGRRKAGEGRSHGRGGEGRGHGKADKG
RGHKSGDEGRDCGKPDDGRGYGKTDEGRGHGRANEG---------RSHEKEGEGRGHERA
DQGRD-HEPGLRRRLALRLA-SLAGLGGSPTAPPGGRSRPLQVPTSPVPDD-AFDQEDWT
PDPKFAVVFPRIHRAGRASSSHSSGEA--SADVPTGEDRGWPGAGEGGHSE--GRRASGE
GVSWPHPGSLLAPTTPDGPSLDESGSSSETESESLDDEPPVHWAQCSGPREGPGLGA-AV
LLPRLALETHQQQEGDLGSRGSQRERWEPEDEAEAVLERDLELSLGPGLETPPLPGAEGR
SLADGLEDAEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1534)

HIFAIVASAYD-LAQNTGQDPCILLCGHSGSGKTEAAKKIVQFLSS
LEQDQTGNRGCQVEDVLPMLSSFGHAKTTLNANASRFSQVFCLYLQQGVIVGACVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSVERERLSLQGPETYYYLNQ-GQACTLKGKEDAQ
DFEGLVKALQGLGLCPEELNAVWAVLAAILQLGNICFSSSEHESQEVAAVSSWAEIYTAA
RLLRVPPEHLEAVIT----RRVTETPYGQVSRSLPVESAVDAR-DALAKALY-SRLFHRL
LKRTNVWLAPPGEGGSIGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE-------------------PPRESCLDLLVDQPHSL-LSILDAQTWLSQVE------
-----------------------FGSRCPGLSA-----MLQSQLTATSASQATDHTFLQK
SHYHHSDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAAVEMLGQSQLQL
VGSLFQE-----------AEP-QSREERGRPTLASRFQQALVDLIARLGR-SHVYFIQCL
SPNPGKYPGLFDVGHVAEQLHQAAILETVGTRSANFPVRLPFEAFLTSRFRALGSEGLED
LSEREKCGTILSQVLGAKSPLCHLGATKV--LLREQGWQQLEELRAQQRSQALLSLHRGL
HTCISGQR----L--LLWMQARV-RGFQARSAGVGARAEVGGPVFTHSSNSCWLTICLLY
-SGKWC----LRRRSALGQLNTILLVAQPLLQ--RRQRLQLG----HWRGWHSSRRASER
VPSMELGRLEIPAELAVMLRMAEGHQDALAGSITESLPPEVPARPNLSLPPDIDRFPFSS
FVSIGFQEPSLPMPGQP-LSKPLTQLDGENPQHALDINRVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQLRPGLRNELFSQLVAQLWQNRDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDEWQDLAGCDFVL
DLISQTEDLGD----PAGPRSYPITPLGLA-------------------EAIPPAPGIQA
PSLPPGPPPGPAPTL-PSR-GHTG---------------------EAQK-SG-SLDSFL-
--DDIFQPVISPSCSDLEQSHTLSSRMKGGGAIGPMQQ-GYPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGAVPAMPPVVVPPQP-----AQPLFPSLDAGQLAVQQQNFINQQAL
ILAQQMTAQAMNLSLEQQTRQQQ-QQR---------------AQASEAASQAPPSAITSK
PKKPP--------TPREESQH--ALESEGG----------SRR-ETSE-EAEDRLCRPKS
FQQKRNYFQKM---GQP----QITVRTMKPPAKIQIPQGEEQEEEEEEEDQEEQEEDR--
-------SAAPS-TIPPPCIVK-KPLKQGG------------AKAAKEAEAEPAKEA-GT
KGRS----------QGLAQGR-GTVVRSLDPKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQP--SRPPKAFLKKSDPKDEALAKL-----------G-----INGA
HLSPLML--TPGPGKGPPPPVAPRPKASIQPGPSGSIKEKQGPLLDLFGQNLPTAQTPP-
---PPPAP---PLLPPKDPETLSVGHLRSTQPMEDQGLSTQLLEPSGSVCFSYTGTPWKL
FLRKEVFYPRENFSHPYCLQLLCEQILRDTFSESCIRISRDERYKMKDLLGDLEVDLNSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGENGSDMQLLAVSHRVLAQGSGLEVGTGDK
------VAPA--HAHP--LCSFAEVLGVECRGSSTLELSLKSEQLVLHTVHARAIRVLAE
LFLSK---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNSSLLS-LHRGDLIKLLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
RHKGQLSNGELGLTRWDRASERPAGPRSQAHSDDSEATSLPSSAAYASLPTDSSNYTMQE
FALRYFRKSEAL-------LGQRGRGAAGKDTDSLVQYTK----APIQESLLILSD-DMS
KQAVASFLALMQFMGDQSKPRGKDDMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQE-QQLRDEIYCQVIKQVTRHPRP
ERCIRGWSFLSLLTGFFSPSTKLMPYLTKFLQDSS-----LNQELAQSSQEHLQRTVKYG
GRRRLPQPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAADVQEELCRQMGIMEPQ
EVQEFALFLIKG----EGELVRPLRPAEYLNNVVVD-QNVSLHSRRLSWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3459)

HFDNSTY
ITTHYSQVLRDYLQGKLPVSAQ--ADAQLARLAALQHLSKANR-NTP-SEQDLLAYVPKQ
LH----RQVNTASIKNLMEQELRRLEGHRPQEAQISFIADLGGQALR---V----PGPQQ
SEFLPASSPPTEAVRQLPLFGHTVYVVLRVSMQALPGSGLLGLNRQHLILMDPSS-----
---QNLCCRIALKSLQRVHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLMDSNA-SCT---EWPSIN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MGAALGEGGEGHGPAC-------------------PPHCHLLPG------------T
AGE-------------------RPGATVQQPRQRTPAAL-LQPDAAGAGGGGVSAGAAVV
GARPSASKGVLPGPLGRPAPQPPEYPGCPDRAV-----------------P

PF00063 // ENSGT00920000148963_7_Domain_0 (1312, 1533)

ATDHTFLQK
CHYHHGEHPSYAKPQLPLPIFTVRHDAGAVTYQVHKFLNTNRDHLDAAVVETLGQSQLQL
VGALFQE-----------AGP-QAQGGRGRPSLAARFQQALGDLVARLGR-SRVYVIQCL
SPNPGKLPGCFDVGHVAEQLRQAGVLEAAGARSVNFPVRVPFGAFLA-RFRALGTAGPED
PSDRERCGTILSQALGAESLLYHLGATKV--LLQEQGWQRLEQLRAQRCSQALLTLHRSL
FSCISRQRLR--L--LPRMQARV-RGLQA-------------------------------
------RKRYLRRRAALGHLNTVLLLARPLLW-RRQ-RLQLG----HRCGWCGDG-ASGT
APSMELGSLEIPAELAVMLKTAEGHQDALAGSITESMPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LAKPLTRLDGENPQHALDINKVILRLLGDGSLQTWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQRRPGLRDELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPMPALQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGTARARPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------TL
DVFTFNEECYAAEVESWTTGEQLAGWILQSKGLEAPPRGWSVSLHSGDAWQDLAGCDFVL
DLIGQTEDLGD----PASPRSYPISALGS-------------------AEAIPPAPGVQA
PSLPRGLPPGPAPTL-PRR-GHTG---------------------GSGT-SG-SLDGFL-
--EHVFEPVFSPGFSDLEHGWALRGRMKGGGAIGPMQQ-GYPM-MYPGMMQMPGYQPA--
-V-VPAPVPMMPAMGTVPPMPTMVVPPQ------PQPLLPSLDARQLAMQQQNFINQQAQ
ILAQQMTTQAMTLSLE-QQTQLRQRQR--Q------------AQALEAAPRAPPSAITPK
PKKPP--------APREEPEP--ELESVSA----------CLREGSSE-EAEDRPRPPKN
FQQKREYFQKM---GRQ----QIKVKTVKPPVKVQIPQEEEQEEQEEEEEWEE---E---
--------PRAVLSPPPTPIVK-KPLKQGG------------AKAAKEAEAEPAKEAEPG
-HDP-----------GPARGR-GPVVRSSDPTR-QQLEPSREIRNIIRMYQSRP--GPVP
M-----------PVQPS--RPFKTFLKKNDPKDEALAKL-----------G-----IQGA
HSSPEML--SP---KGPPPAVAPRPKALPQPGPSSSIKEKQEPLRDLFGQNPPTAQAP--
-----QPPPAPPLPPPEDPGAPSAEPRGLMEPMGDQGTATQLLVPSGSVCFSYASAPWKL
FLRKEVFYPRENFSHPYCLRLLCEQILRDTFAESCIRISQDERRKMKDLLGDLEVGLDSL
ATAEDSIKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTQGPS
------FRPN--QLKILCSYSFSEVLGVECPLGSTLELSLKNEQLVLHTARARTIKAMVE
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDCSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSARGRSGLFPADIVQPATAPDFSFSLAQRSS
LRKHHSQLREPGLAQQDRASEVRKTGEAEARPPQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
-----------AEENGGCRRPGAGSPPEAQERQGSARRQGRGPRGGR------RGRLE-G
SLSRGEGR----GGRRRRKGKDRGPSAQRGRRAPRSLDGDTSGGNGGSSCPDSEAREAQE
SGSQHGGAQELRPTLEPTVTGSEGTKTGPESA-LE---PSSDGLDSDWPRADSWG-RERS
SGTGPLGASEHSGGDSDSSLLETGPGRGPRAAM--ASRT-----FEG--------S----
---SRAPRDTGPAQDASDNRAQ-----RGTKPETMQALTARDPRHPIGKAAGRVPAAAGE
GEAGAPAGA-----GPEDPAPLAALLVVRRLFARSLPGATSQAVGPSRAGLKERLLNVAR
ALGLLRWLRRRLRLRPRPPEGKGQGAGPPASEGWGRGKAFEGRG---------SGKADEG
RGHKRGDEGRCHGKEDEGRGRERADEGRDRER------------------ADEGRGGERA
DEGRR-PEAGLRHSVALRLA-GLAGLGGRPRAPPGVLSRPPQVRTSPVPDD-PFDQEDGT
PDPKFAVVFPRIHKAGRASSSRSSEEA--STDAPTGEGRGWPRAGAGGHS--EGRRASGE
GVSGLRRGSLLSPTAPDGPSLDESGSSSETESETLDDEPPVHWAQGSGPRKGPRLGA-AV
LLPRLALETRLQQEG-PGLRGSLRERWEPEDEDEAVLERDLELSLGPGLEVPPFPGAEGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQHTGQDTCILLRGHSGSGKTEASKKIVQFLSS
LEQDQTGNRGCQVEDVLPILNSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLVKALQGLGLCPEELNAVWAVLAAVLQLGNICFSSSERESQEVAAVSSWAEIHTTA
WPW-------RAAVT----RRVTETPYGQVSRSLPVEGAIDAR-DALAKALY-SRLFHRL
LRRTNARLAPPGEGGSIGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLDLLVGQPHSL-LSILDAQTRLSQTE------
-----------------------FGSCCPGWSA-----MVRSRFTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVPGLRDRPGVDEQAPAASWLSSSPPQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFEAFLA-RFQALGSEGQED
LSDREKCGSILSQVLGAESALCHLGATKV--LLQEQGWQRLEELRDQQRSQALVNLHRSF
HTCISRQ--R--V--LPRMQARM-RGFQARSASIGARAEVGGVRLLDS----SFR---PR
-PLPASRKRCLRRRAALGQLNTILLVAQPLLR--RRQRLQLG----HWQGWHSSKRAVER
VPSMELGRLEIPAELAVMLKTVEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LAKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSTFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDTWQDLAGCDFVL
DLISQTEDLGD----PAAPHSYPITPLGSA-------------------EAIPLAPSIQA
PHSPRP---GPW-HQ-PSP-CPTG---------------------EVQR-PG-SLDGFL-
--DQIFQPVMSSGLSDLEQSWALSSRMKGGGAIGPTQQG-YPM-VYPGMIQMPGYQPGM-
---VPAPMSMMPAMGTVPAMPAMVVPPQL-----P---LPSLDSGQLAIQQQTFINQQAL
ILAQQMTAQAMTLSLEQQTQQ---RQQQAQASEA--------A------SQALPSAITSK
PRKPP--------TPLEKPQH--DLESEDG----------CLRVR-SW-AS---------
VVTWKAIWTLA---GQP----QITVRTVKPPDKVQIPQGEVQEEEEEEQEEEEQ------
-EEQEVETGAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
GRGQE-----------PAQGR-GIVVRSSDPKS-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKAFLKKINPKDEALAKL-----------G-----INGA
HSSPPML--FPSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLTPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLDSL
TTTEDSIKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRALAQDPGLEVGAGGK
------VTPA--HARPLC--SFAEVLGVECRGSSTLQLSLKSEQLVLHTARARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
WHKGQLSNGEPGLARWDRASERPAHSWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMQE
FALLF-PRGSAL-------LGQTDGGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLALMRFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQE-EKLRDEIYCQVIKQVTGHPRP
EHCARGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRRMPPPGEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFALFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3484)

HFDNSTY
ISTHYSQVLRDYLQGKLPVSAK--ADTQLARLAALQHLSKANR-NTP-SEQDLLAYVPQQ
LQ----RQVNTASIKNLMDQELRQLGGHSPQEAQISFI----------------------
-EFLPAPSPPAEAVSQLPLFGYTVYIALRVSMQALSGPALLGLSRQHLILMDPSS-----
---QNLYCRIALRSLQRLHLLSPLEEKGPPGLEVNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------LS----SWQAWCKNQ-R-KR
GSRMELERLEIPAELSALLTTAEDRQHVMAESITEALPPEVTAQDELALPPDIDRFPFSR
FISENFQXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXMLRLLGDQSLQA

PF00784 // ENSGT00920000148963_7_Domain_3 (1793, 1857)

WQEQTMGT
YLAQQGQRHSALRNEIFCQLVTQLWHNPDEQQSHRGWALMAILLSAFTPTLTLQKPLLXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XX
XXXXXXXERYSAEVKSWTTGEEFAGWILRTRGIEQPIRGWSVSLLSGDSWKDLGGCDFVL
DLIGQTEDLGD----PSAPESYPITPYNMT------------------SEDIPPPPRIQA
PPLTPEPPPSPAPSL-PQR-SYTR---------------------ESQS-PR-SLNGFL-
--DNLFEPVLSSGPSDLEQARALNSRMKGGGGIGTQQ-GGYPM-MYPGMMQMPSYQPAMG
AM-MPAPVPLMPAMGGIPAMPAMMMPSQ------SQPVMPMPSARELAAQQQSFINQQAM
ILAQQMTTQAMTLSLEQQAQRQHL------------------NQAS--TSASLPLPT-PK
PKKFP--------TPKAEPQR--SLEGTGL------------RES--FEDGEEKLMHPNT
FQEKRDYFQKI---GQD----PIQLKKVKLPAKVPIPQREIEQEEEEEIKGEDGKEP---
----------PSPPSHPPPVAK-KPLKKKEGGDKPNSEDGAGAKAGNEAKA-------EP
KNQK-----------PKREGK-STVVRSSKPVH-KLEEPSKEIRNIIKMYQSRP--APAP
E-----------PVQPIR--PQKSFIKKNDPKDEA-AKL-----------G-----LNGN
CLLLLPS--ALGSKKDLPPP-VARR-PKSHLQSSSSIKEKQRPLMDLFAPVQSTTSTP--
-----QSPTLPPPPPPPCPLSLSSEP---FPSMGDEHINTQLLHPSSSISFAYTSATWKL
FLRKEXXXXXXXXXXXXXXXXXXXXILRDTFTESCIRISPDERNKMKDMLAALQVGMDAS
TITEDSIKKRIVVAARDNWDNYFSRIFHVSGESGSDIQLLAVSHRGLRL---LKVVNNAT
------FLTD--HLKTLCSYSFAEVLEVKAQGHNVLQLSLRNEQLILHTTQAQTIKSLVD
LFLNE---LKXXXXXXX-XXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXX----------
------------------------XWQFGSTGGRSGLFPSDMVKVAAALDYLTFPKEQRD
GSQRSPPRGEPGLSPQNWTTEVRELG----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

MGRNQGKTPQRLARPGRPASGEQESGSASADG-APSQERRSDRGQAVRARPAAEPATAGG
QGTAGGRRKPTAEENGGCRRPGAGSPPEAQERQGSARRQGRGPRGGR------RGRLE-G
SLSRGEGR----GGRRRRKGKDRGPSAQRGRRAPRSLDGDTSGGNGGSSCPDSEAREAQE
SGSQHGGARELRPTLEPTVTGSEGTKTGPESA-LE---PSSDGLDSDWPRADSWG-RERS
SGTGPLGASEHSGGDSDSSLLETGPGRGPRAAM--ASRT-----FEG--------S----
---SRAPRDTGPAQDASDNRAR-----RGTKPETMQALTARDPHHPVGKAAGRVPAAAGE
GEAGAPAGA-----GPEDPAPLSALLVVRRLFARSPSGATSQAVGPSRAGLKERLLNVAR
ALGLLRWLRRRLRLRPRPPEGKGQGADE-------------GRG---------GER----
-----------------------ADEGRGGER------------------ADEGRGGERA
DEGRR-PEPGLRHRVALRLA-GLVGLGGRPRAPPGVLSRPPQVRTSPVPDD-PFDQEDGT
PDPKFAVVFPRIHKAGRASSSRSSEEA--STDAPTGEGRGWPRAGAGGHS--EGRRASGE
GVSGLRRGSLLSPTAPDGPSLDESGSSSETESETLDDEPPVHWAQGSGPRKGPRLGA-AV
LLPRLALETRLQQEG-PGLRGSLRERWEPEDEDEAVLERDLELSLGPGLEVPPFPGAEGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLRSSYPPC--------------PHLCEF

PF00063 // ENSGT00920000148963_7_Domain_0 (881, 1533)

GHSGSGKTEASKKIVQFLSS
LEQDQTGNRGCQVEDVLPILNSFGHAKTILNANASRFGQVFCLYLQQGVIMGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLVKALQGLGLCPEELNAVWAVLAAVLQLGNICFSSSERESQEVAAVSSWAEIHTTA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPVEGAIDAR-DALAKALY-SRLFHRL
LRRTNARLAPPGEGGSIGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLDLLVGQPHSL-LSILDAQTRLSQTE------
-----------------------FGSCCPGWSA-----MVRSRFTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVPGLRDRPGVDEQAPAASWLSSSPPQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFEAFLASRFQALGSEGQED
LSDREKCGSILSQVLGAESALCHLGATKV--LLQEQGWQRLEELRDQQRSQALVNLHRSF
HTCISRQ--R--V--LPRMQARM-RGFQARSASIGARAEVGGVRLLDS----SFR---PR
-PLPASRKRCLRRRAALGQLNTILLVAQPLLR--RRQRLQLG----HWQGWHSSKRAVER
VPSMELGRLEIPAELAVMLKTVEGHQDALTGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LAKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSTFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDTWQDLAGCDFVL
DLISQTEDLGD----PAAPHSYPITPLGSA-------------------EVIPLAPSIQA
PSLPPGLPPGPAPTL-PSR-DHTG---------------------EVQR-PG-SLDGFL-
--DQIFQPVMSSGLSDLEQSWALSSRMKGGGAIGPTQQG-YPM-VYPGMIQMPGYQPGM-
---VPAPMSMMPAMGTVPAMPAMVVPPQL-----P---LPSLDSGQLAIQQQTFINQQAL
ILAQQMTAQAMTLSLEQQTQQ---RQQQARASEA--------A------SQALPSAITSK
PRKPP--------TPLEKPQH--DLESEGG----------CLRVR-SW-AS---------
VVTWKAIWTLA---GQP----QITVRTVKPPDKVQIPQGEVQEEEEEEQEEEEQ------
-EEQEVETGAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
GRGQE-----------PAQGR-GIVVRSSDPKS-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKAFLKKINPKDEALAKL-----------G-----INGA
HSSPPML--FPSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLTPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLDSL
TTTEDSIKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRALAQDPGLEVGAGGK
------VTPA--HARPLC--SFAEVLGVECRGSSTLQLSLKSEQLVLHTARARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
WHKGQLSNGEPGLARWDRASERPAHSWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMRE
FALLF-PRGSAL-------LGQTDGGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLALMRFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQE-EKLRDEIYCQVIKQVTGHPRP
ERCARGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRWMPPPGEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFALFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3459)

HFDNSTY
ISTHYSQVLRDYLQGKLPVSAK--ADTQLARLAALQHLSKANR-NTP-SEQDLLAYVPQQ
LQ----RQVNTASIKNLMDQELRQLGGHSPQEAQISFIADLRGQA------------AQQ
PEFLPAPSPPAEAVSQLPLFGYTVYIALRVSMQALSGPALLGLSRQHLILMDPSS-----
---QNLYCRIALRSLQRLHLLSPLEEKGPPGLEVNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------NVADLVRHTK----VPIQASLLRYSDSELS
ELATKNFQTLMRFMGDRPKHKHQT

PF00784 // ENSGT00920000148963_7_Domain_5 (3145, 3254)

EVQCIYEILQLCKEKENLHDEIYCQVIKQVTHNPQQ
ESELRGWLLLNLLTGYFLPSKILMPYATKFLQLASNCL-----YIAKICQSNLRKNFLYG
GRRHLPFPVEMEA

ENSGT00920000148963_7_Linker_5_6 (3254, 3353)

LLKGHGARRLVVLMPGGMEYLTRIRTFTVAKELLQEICEQMGIGEQQ
EIQDFVLFAIRS------KMVRPIKLEEYLHDYLLEDKLVTVTLRRLIWRTP

PF00373 // ENSGT00920000148963_7_Domain_6 (3353, 3505)

LHFDNEVY
TDVHYGQVLWDYLNGRILLNQSKEMEMQVGLLAMLQHWAKVEQQNSAPSREELKEYTPKT
LQ----SSISPKALHSHVATLLRTRPPLQPRDAKIQFIE---------------------
------------HVMKLPFFGYTIFIVERISEGMIPVPCFFGVNKEEIIAVDVTT-----
---QAVSQVILLKELQKMRTLRPMSDGGLPGLELHYGSPGSPKALWVELSQAKELYHTIV
VMLD-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MKEAPGVRGGHSPMYP--PCCRMPPGPAGEWPGAAVQQPRQRAPAAL
L---QPNAAGPGGGGVSAGVAVLGA----------------CPSASEG--------V-L-
-PG-------------------PPGRPA-----------------PQPLEYPGR------
-----------------------PDMAVPGSSA-----MLQSQLTATSA

PF00063 // ENSGT00920000148963_7_Domain_0 (1310, 1534)

FQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAAMEMLGQSQLQL
VGSLFQE-----------AEP-QSRGERGRPTLASRFQQALGDLIAQLGR-SHVYFIQCL
SPNAGKHPGLFDVGHVAEQLHQAAILEAVGTRSANFPVRLPFEAFLV-RFWALGSERQED
LSQREKCGTILSQVLGAESPLCHLGATKV--LLREQGWQQLEELRAQQRSQALLSLHRGL
HTCISSQR----L--LLRMQARVLRGF---------------------------------
----QCPKRCLRRRAALGQLNTILLVAQPLLQ--RRQRLQLG----HWRGWHSSRRASER
VPSMELGHLEIPAELAVMLRMAEGHQDTLAGSITESLPPEVPARPNLSLPPDIDRFPFSS
FVSIAFQEPSLPMPGQP-LSKPLTQLDGENPQHALDINRVILRLLGDGSLESWQRQT

PF00784 // ENSGT00920000148963_7_Domain_3 (1798, 1903)

MCT
YLVRQGQRRPGLRNELFSQLVAQLWKNQDEQQNQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLTPGATRAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------TL
DVFTFSEECYSAEVESWTTGEQLAGWILQSRGLEAPPRGWSVSLHSRDEWQDLAGCDFVL
DLISQTEDLGD----PAGPRSYPIAPLGST-------------------EAIPPAPGIRA
PALPPAPPPGPAPTL-PSR-GHTG---------------------EAQR-SG-SLDSFL-
--DDIFQPVISPGHSDLEQSRTLSSRMKGGGAIGPTQQ-GYPV-AYPGMIQMPGYQPGM-
---VPAPMPMMPAMGAVPAMPPMVVPPQP-----VQPLLPSLDVGQLAIQQQNFINQQAL
ILVS---AQQMTLEQQTRRQQQ--QRQ---------------AQASEAASKAPPSAIISK
PKKPP--------TPPEESQH--ALESEGG----------SQR-ETSE-EAEDRPCQPKS
FQQKRNYFQKM---GQP----QITVRTMKPPVKIQIPHGEEQEEAEEEEE--------Q-
EEQ--EEDRTPS-TLPPPCIVK-KPLKQSG------------AKAAKEAEAEPAKEA-AT
KGRS----------QGPAQGR-GTVVRSSDPKP-KQPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQP--SRPPKAFLKKSDPKDEALAKL-----------G-----INGA
HLSPLML--SPGPGKGPPPAVAPRPKVPLQPGPSSSIKEKQGPLLDLFGQNLPTAQTPP-
---PPPAPPAPPLLPPKDPETLSVGHHCSTQPMEDQGLSTQLLEPSGSVCFSYTGTPWKL
FLRKEVFYPRENFSHPYCLQLLCEQILRDTFSESCIRISRDERHKMKDLLGDLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGENGSDMQLLAVSHRGLRL---LKVTQGPG
------LHPN--QLKILCSYSFAEVLGVECRGSSTLELSLKSEQLVLHTVRARAIRALVE
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2984)

YVI-ALRSYITDNSSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIAQPAAAPDFSFSKEQRSG
RHKGQLSNGELGLTRWDRASEVRKTGEGKPEAMPA-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

MGGSKGKAPQHRARPRKPASGEQESGSASADGQP-------GRGQARRD-------TAGD
KRAAGDRRKPSAAGGSGGRSP----ETEARERRGSTRRRGQGPVDGCEPGDSPGDCPEEE
EGLPGAARTGKRGHRRRRGKRRRGPSAPRSRGEPRSLDEDTSGRDGGSSCPDSEAREPQE
SG----GAPP----------------------------------P---------------
---------GGSGTDTGSNPERAGPARRPPRAR--GKAGRVPEARETELGGKAPTSSP--
-LGSSSSRDAWDA--------APDGDASGGD-------------------ARAEASTAGA
RRPREGEGDGAGDPEPGDPAPLAALVVLHKFRARPPPGRAPQVAEQRRGGFKAWILRVAR
ALGLLRWLRGRIQSP----AGQGQGAGPRAEEGRGLLRE---------------------
------------------------------------------------GEGCEGRGLGRA
GEGRG-EGPAPPRRRLALRLAGLARLRGLLRAPPGGGSSPPQAPRSPVSDHRPSDDEDPT
PDPKFAVVFPRIHRAAGRAS---A-AT--PSRAWSGAGA-------AEAG--EGPGAGGE
GVRGLGDASAPASTPLDGT----P--RREEEPVTSGAETPAHWAQGCGPQEEPGLGP-AA
LLPRLTLETRVPRERSP--GPALREQWEPEDEAEAALERRLELSLGPGLRTPPFPGAEDR
TLSEGLED

PF00063 // ENSGT00920000148963_7_Domain_0 (789, 1170)

TEDVARLRLVSDSSVLLCLKRRFHLGRIYTFGGPLLLALNPHQPLPVFSPEV
LTSYHPRKAPSSSPHIYAIMAAACG-LSQSAGQDPCILLAGHSGSGKTEAAKKMVQFLSS
LDQK-------QLDDVLPVLSSFAHAKTILNANASRFGQVLCVCLQREVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLGGLGPMEREQLSLQGPETYHYLNQ-GRACRLQGKEEAL
DFAELAKALQALGLRPEELTAVWTVLAIILHLGNICFSSSEREFQEVAAVSSWAEIHTAA
RLLQVPPEQLAGAVT----TRVMETPYGRVSRSLPVESAIDAR-NALAKALY-LRLFSWL
LRRINTRLAPPAEGGSVGSVTVVDAYGFEVTPG--VGGSA----------HLFLTMN---
----VWGGSLFPWSHLA-------------------------------------------
------------------------------------------------------------
----------------------LRDSAQ--------------------------------
----AQS-----------SSP-TADKKRK-------------------GN------TCCS
D---------------------------------------LTSASVD-RFQALGTEGQGD
CSDRERCGAILTQVLGAESPLYHLGVTQV--LLQEQGWQQLERLWAQRRAQALLTLHRGL
RVCISRQRLR--L--LPRMQARV-RGLQA-------------------------------
------RKRYLRRRAALGQLNTILLVARPLLH--RRQKLQVR----GLAEA-----GVGR
LGVEDLGRLEIPAELAAMLRRAEGDQDVLAGTIKESMPPEVPARPSLSLPADIDQFPFSS
FVSISFQEPSLPSPGQP-LTRPLTRLDRETPQHALEINKVMLRLLGDGSLQPWQEHT

PF00784 // ENSGT00920000148963_7_Domain_3 (1798, 1903)

MGT
YLVRQGLRRPGLRDELFSQLVTQLWRNPDEQQSQRGWALMAILLSAFPPTPALQKPLLKF
VSDQAPKGMAALCQHKLLEALAQTPLAPGAARTHPPTQLEWK

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFNEECFSVEVESWTTGEEFAGWILQSRGLEVPPRGWSVSLHSEDAWQDLSGCDFVL
DLIGQMEDLGD----PADPHSYPFTSFDLA-------------------EDIPPAPGVQA
PSLPPGLPPGPAPTL-PSR-YHTG---------------------EAS------------
-----------AAPSDLDQGWALSSRMKGGGSVGPSQQQGYPM-VYPGMMQMPGYQPAM-
---VPAPVPMMPAMGPIPAIPAMMVPPPP-------PQLPSLDTQQLAVQQQNFINQQAL
ILAQQMTTQAMSLSLEQQSQQRQ-RQAQA----------------SRATSQAPSPATTPK
SKKPP--------TPQEVPES--DPEPTGA----------CWREDFAE-EAEHSPGHPES
FQQKREYFQKM---GQQ----QIKVKKVKSPPKVQIPQGGETEEEEEEESRA--------
-----------------------------G------------RTAAREAEAEPAKEAVPA
RAR-------------------EPRPHSSNPTP-QRPEPSKEIRNIIRMDWGCLAPQEMP
P-----------PHPQTW--PPKTFLKKNDPKDEALAKL-----------G-----IHST
QST-----------WARLPTVAPKPKALPRLGPSSSIKEKQGPLQNLFGPNSPIAQTPPL
P-------PAPPLPLPEEPSISSVEPRALREPMEDQGVCTQLLTPSGSVCFSYASAPWKL
FLRKEVFYPRENFSHPYCLQLLCEQILRDTFAESCIRISPDERHRMKDLLRDLEVGLDSL
AAAEDSVKKRIVVAARDNWANYFSRIFPVSGERGSDVQRLAVSHRGLRL---LKVVQVPS
------FHLD--QLKTLCSYSFAQVLGVECRGSSALELTLKGEQLVLHTPQARAIKAMVE
QYLEE---LRKGSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FHRGDLIKLLPGTTLEP----------
------------------------GWQFGSVGGRSGLFPADMVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3152)

PAAAPDVSFLSEQKPS
WQRKSQAQ------------PREPHPAYS---DDSDATSLPS-SEYPPLSSEPHNYTMQE
FALRYFRKPHTM-------CST----------------------TPIQESLINTNDEDTN
SKAVAGFQVLMQYMGDQSKPRGKKEPELLYE

PF00784 // ENSGT00920000148963_7_Domain_5 (3152, 3253)

LLKLCRE-EQLRDEMYCQVIKQVTGHPQP
ERCVRGWSFLSLLAGFFLPSTTLMPYVTKFLQDSG-----PNQELARSSQEHLQRTVKYG
GRQQLPLPGEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRMLLIHLPGGLDYKTNLHTFTVAGEVLEELCGQMGITDPQ
EVQEFALFLIKG----EGDLVRPLRPPEYLNSVLVA-PDLSLHSRRLGWESPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPTY
IDTHYGQVLRDYLQGKLMARAQ--AEAQLAQMAALQHLSRASK-DPP-SEQDLLAYIPKP
LQ----WQVNMAAIRSLLSQELRQLKDYDPQEAQISFIR---------------------
--------------AQLPLFGYTVYVVLRVSKMVFPGPVLLGLNRRHLVLMDPSS-----
---QKLCCSIDLKHLQRLHLLSPLEENGPPGLELNWGSADSPQTMWVELPQAQELQHTIV
FLMEGSG-SSSQ---------

MGRNQRKAPQRLERPGRPASGEQESGSASADG-APSRERRSDRGQADRAKPAAEPATAGG
QGTPGGRRKPTAEGNGGCRRPGAGLSPKAQERQSNAQRQGRGPRGGR------GGRLEEG
SLSGGEEL----GGRRRRKRKDKGPSARRGRRTPRSLNGDTSGGDGGSSCPDSETREAQE
SGSQRGTARELRPTPEPTDMGSEGTKTGPESALEP----S-SDGLDSDWPHADTRGREGS
SGTGPLGASEHSGGDSDSSPLGTGPGRGSRAAM--ASRT--------------------F
EDSSRAPRDTGPAKDASDNRAQ-----RGAEPETMQASTARAPRHQVGKAVGQVPAAAGE
GEAGAAAGA-----GPEDPAPLAALLVVRRLLARPPPGAASQAVGPRRAGLKERLLSVAR
ALGLLRWLRRRLRLRRRPPEGEGQGTGPRASEGWGRRKPDEGRGHGRGSKGRGRGKADEG
RGHERGDEGRGRGKADEGRGHERGYEGRGCGKADEG---------RGHERGDEGRDHQRG
YEGWGRE-PGLRHRLALRLA-GLAGLGGMPRASPGGRS--PQVPTSPVPGD-PFDQEDET
PDPKFAVVFPRIHRAGRASSSRSSEEA--SADAPTGEGRGWPRAGVGGHS--EGCRTSGE
GVSGLRRGSLLAPTAPDGPSLDESGSSSEAELETLNDEPPVRWAQGSGPHEGPRLGA-AV
LLPRLSLETRLQQEGDPGLRGSLRELWEPEDEDEAVLERDLELSLRPGLEAPPFPGAKGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQNTGQDPCILLCGHSGSGKTEAAKKIMQFLSS
LEQDQTGNRECQVEDMLPILSSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYKLLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLLKALQGLGLCPEELNAVWAVLAAILQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPVESAFDAR-DALAKALY-SRLFHRL
LRRTNARLAPPGEGGSIGTVTVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE-------------------PPRESCLDLLVDQPHSL-LSILDAQTWLSQTE------
-----------------------FGSCCPGWSA-----MVRSRLTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALEDLIARLGR-SHVYFIQCL
TPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFEAFLA-SFQALGSEGQED
LSDREKCGAVLSQVLGAESPLYHLGATKV--LLQEQGWQRLEELRDQQRSQALVDLHRSF
HTCISRQR----V--LPRMQARM-RGFQARSAGVGARAEVGGPVFTHSSNSCWLTVCLIY
-PWARCWKRYLRRRAALGQLNTILLVAQPLLQ--RRQRLQLG----RWQGWHSSERALER
VPSMELGRLEIPAELAVMLKTAESHRDALAGSITECLPPEVPARPSLTLPADIDLFPFSS
FVAIGFQEPSLPRPGQP-LAKPLTQLDGDNPQRALDINKVMLRLLGDGSLESWQRQIMG

PF00784 // ENSGT00920000148963_7_Domain_3 (1800, 1903)

A
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLASGATRAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDAWQDLAGCDFVL
DLISQTEDLGD----PARPRSYPITPLGSA-------------------EAIPLAPGIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVISSGLSDLEQSWALSSRMKGGGAIGPTQQ-GYPM-VYPGMIQMPAYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP--------PLPSLDAGQLAVQQQNFIQQQAL
ILAQQMTAQAMSLSLEQQMQQRQ--QQ---------------ARASEAASQASPSAVTSK
PRKPP--------TPPEKPQR--DLGSEGG----------CLR-ETSE-EAEDRPYQPKS
FQQKRNYFQRM---GQP----QITVRTMKPPAKVHIPQGEAQEEEEEEEEE------EE-
QEEQEVETRAVP-SPPPPPIVK-KPLKQGG------------AKAPKEAEAEPAKET-AA
KGHG----------QGPAQGR-GTVVRSSDSKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQP--SRPPKAFLRKIDPKDEALAKL-----------G-----INGA
HSSPPML--SPSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPIAHTPP-
---PPPAP---PLPLPEDPGTLSAERRCLTQPVEDQGVSTQLLAPSGSVCFSYTGTPWKL
FLRKEVFYPRENFSHPYYLRLLCEQILRDTFSESCIRISQNERRKMKDLLGGLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRALAHDPGLEVGAGGK
------VTSV--HARS--LRSFAEVLGVECRGGSTLELSLKSEQLVLHTARARAIEALVE
LFLNE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
WHKGQLSNGEPGLARWDRASERPAHPWSQAHSDDSEATSLSSV-AYAFL-PDSHSYTMQE
FARRYFRRSQAL-------LGQTDGGAAGKDTDSLVQYTK----APIQESLLSLSD-DVS
KLAVASFLALMRFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQQ-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGFFPPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRRMPPPGEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAAEVQEELCRQMGITEPQ
EVQEFALFLIKE----KSQLVRPLQPAEYLNSVVVD-QDVSLHSRRLHWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3459)

HFDNSTY
ISTHYSQVLWDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NTP-SGQDLLAYVPKQ
LQ----RQVNTASIKNLMGQELRRLEGHSPQEAQISFIADLGDQAEQ---V----PGPQQ
SDFLPAPSPPAEAMSQLPLFGYTVYGVLRVSMQALSGPTLLGLNRQHLILMDPSS-----
---QSLYCRIALKSLQRLHLLSPLEEKGPPGLEVNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SCT---EWPSIN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

PF00784 // ENSGT00920000148963_7_Domain_5 (3158, 3255)

SREELRDEI--QAVKQVMGHPQP
EHCARGWSFLSLLTGCFPPSTTLMPYVTKFLQDAG-----RSQELARSCQEHLQRTVKYG
GRRCLPPPGEMQAFLKGQAVRLLLVHLPGGVDYKTNVRTFTVAAEVLEELCGQMGVTDPQ
EVQEFALFLIKG----EXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX--XXXXXXXXXXXX-------X-XXXXXXXXXXXX-XXX--X-XXXXXXXXX
XX----XXXXXXXXXXXXX--XXXXXXXX-----XXXX----------------XXXXXX
XXXXXXXXXXXXAMCRLPLFGYTVYVVLRVSELALPGPGLLGLNCQHLILMDPSS-----
---QKLCCSIMLRDMQRLHLLSPLEEGGLPGLELNYGSADSPQTIWFELPQAQELKHTIA
FLLDSSAS-S----IYPGLAQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------PSLPAMMVPPQP-----PQPVLPSLDASQLAVQQQNFINQQAL
IMVRQMTTQAMTLTLEQMQQRQR------Q------------TQASGAASPAPPPATTPK
PRKPP--------TPREEPAR--DLESASA----------SLR-EPTE-EAQDRPWHPKS
FQQKRDYFQKM---GQQ----QIKVKVVKPPAKVQIAKAEEQEEEEEEEARAGGGRR---
-----WVGAASPPSPPPPPVVR-KPLKQGG------------AKAANEAEAEPAEEAGPG
GGGR-----------GPARGR-EPMAQSTEPTV-QRLEPSREIRNIIRMYQSRP--GPVP
V-----------PVQPS--RLPKSFVKKNDPKDEALAKL-----------G-----INGA
YSPPLTQ--PPSLGKGPPPAVAPRPKAPIQPGTSSSIKEKQGPLRDLFGQTPPSPGAP--
-----PPPPAPPLPLLGDPETHSAEPRVLIEPMSDQGVSTQLLVPSGSVCFSYTGAPWKL
FLRKEVFYPRENFSHPYCLRLLCEQILRDTFTESCIRISQKERSRMKDLLGDLEVGLDSI
ASTEDSVKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTQGSS
------FHPD--QLKTLCSYSFAEVLGVECRGTSTLELSLKSEQLVLYTVRAGTIKSMVD
LYLNE---LKKDS

PF00018 // ENSGT00920000148963_7_Domain_4 (2894, 2986)

DYVI-ALRSYITDDSSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSCGGRSGLFPADMVQPAAAPDFSM--KQQSS
RRRSAVQRGEPGLAPGAEASEVR-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------EIPAELAVMLKTAEGQQDALAGSITESMPPEVPARPSLALPTDVDRFPFSS
FVSIGFQEPSLPRPGQP-LTKPLTQLDGENPQRALDINRVMLRLLGDGSLQSWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1866)

GT
YLVRQGQHRPKLRDELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPMPALQKPLLKF
VSDQA

ENSGT00920000148963_7_Linker_3_4 (1866, 2895)

PKGMA----------------------------LEWMAGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLA-----------PPRGWSVSLHSEDSWQDLAGCDFVL
DLVGQTEDLGD----PASPRSYPIAPLGLA-------------------EAIPPAPGVQA
PSLPPGPPPGPAPAL-PTR-GHTG---------------------ETRA-PG-SLDGFL-
--DHLFQPVLSPGLSDLEQGWTLSDRMKGGGAVGPTQQ-GYPM-VYPGMMQMPGYQPAM-
---MPAPMPMMPAMGAVPAMPAMVVPPQPQPP--PQPLLPNVDARQLALQQQNFINQQAL
ILAQQMTTQAMTLSLEQQTQQWQ--RQ---------------ARGSGAASQAPPPVITPK
ATKPP--------APQKEPET--ELEARGA----------CLK-ETLE-EADDRPRRPKS
FQQKRNYFQKM---GQQ----QIMVKTVKPPAMVQMPQEETPEEQEEAAEAGGGG-----
-GESRQEGWALS-PPPLAPVVK-KPLKQGG------------AKAAKEAAAEPAKEAG--
PSHG----------QEPAQGR-GPVVRSLDPTP-PRQKPSREIGNIIRMYQSRP--GPVP
V-----------PGITLWTWTPKAFQKKNDPKDEALAKL-----------G-----IYGA
HSPPSTL--SPGLGKGPPPVVAPRPKAPLQLGPSSSIKEKQGPLRDLFGQNPPAPQAPP-
---PPPVP---PLPLPEDPETLPAEPHGLVEPMRDQGPPTQLLVPSGSVCFSYASTPWKL
FLRKEVFYPRENFSHPYCLQLLCEQVLRDTFAESCIRISQDERRRMKDLLGDLEVGLDSL
ATAEDSVKKRIVVAARDNWANYFSRIFPASGESGSDVQLLGVSHRGLRL---LKMTQGPQ
PRREVGGAMA--SAHALPVHSFAEVLGMECRGDSTLELSLKTEQLVLRTARARAIKAMVE
LFLNE---LKQDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDCSLLN-FHRGDLIKLLPVTSLEQ----------
------------------------GWQFGSVGGRSGLFPANIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3149)

PAAAPDFSFLPEQRSS
RRKSQLSLGEPGLARWDRASEYPARPRSQVYSDDSEATSLPSSVAYASLSIESHNYTMQE
FALRYFRKPA-----------PTGGGAEGKVIDSLVQYTK----APIQESLIILRDEDTS
KQAVASFQALMQFMGDRSKPRGKDELDL

PF00784 // ENSGT00920000148963_7_Domain_5 (3149, 3253)

LYELLKLCRE-EQLRDEIYCQVIKQVTGHPRP
ERCARGWSILSLLTGFFPPSTTLMPYVTKFFQDSG-----PSQELARSSQEHLQCTVKYG
GRRRLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3355)

AFL--------------------------VAAEVLEELCREMGITEPQ
EVQEFALFLIKG----EGQLVRPLRPCEYLNSVVVD-QDVSLHSRRLGWETALH

PF00373 // ENSGT00920000148963_7_Domain_6 (3355, 3463)

FENPNY
ISAHYSQVLRDYLQGKLLVSAQ--ADAQLARLAALQHLSGANK-DSP-SEQDLLAYIPKP
LH----RQVNVATIKSLMGQELRQLQGHSSQKAQISFIGAAEVSPSALLLSPDPGGRAGQ
SELLPWPSPPPEAMSQLPLYGYTVYVVLRVSNLALPGPALLGLNCQHLILMDPSS-----
---QKLCCSITLKALQRLHLLSPLEADGPPGLELNYGSADSPQTIWFELPQAQELLHTII
FLLDSSN-SCT---EWPGLY-

MGGSKGKAPQRRAQPRRPASAEQESGSASADG-APSRDRRLARGKAHKARPAKEPDATED
EGTSGGRRKSTEET-------R-----E--RQGSSQRPRGRRPTESREPGDSRGELREEQ
RLPKRG------RRR-R--GKERGPSA-------PGRDADTSGGDGGSS-----------
-------SSERPTKTEPGDTGSEGALIRSPGA------TG-SSHQDNGGHALGLRSGEGP
SGSGPRGAGDDSRTDADSSSGW--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----FAVVFPRIHSAEKESGGGSS-GA--STDAPTGEGA-------AEYR--EEQGAREE
GVVRSHQPPSFSPSAPDGTPPDEN--RSEAEPDTLEVESRVHWAQGSTPCADPGVGT-GT
LLPQLTLETRLQ-QNSP--CRSPREQWEPEDDAEAALERALELS----LEMPPFPGAKTR
SLPEALED

PF00063 // ENSGT00920000148963_7_Domain_0 (789, 1529)

TEDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPLLLALNPHQPLPLFSPEI
LASYHPRKAANTTPHIFVVGAAAYR-LSQSAGPAPCILLGGHSGSGKTEAAKKIVEFLSS
LGQKQAEARGAQLEDILPVLSSFGHAKTILNANGSRFGQELCLCLHHGVNVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDPGDRELLSLQGPEAYYYLNQ-GQTCRLQGKEDAQ
DFKGLVKALQVLGLCAEELSEVWAVLATILHLGNICFSSSERESQEVAALSSWAEIHLAA
RLLRVPPERLEGAIT----KRVLDTPYGRVSRSLPVESAIDAR-DALAKTLY-TRLFNWL
LKQINVLLAPPREADSVATITVVDAFGFEALRV--NGLEQLCSNLASERLQLFSSQRLLA
QEEEECQREMLSWVPIPQ---P-RRESCLDLLAGQPHSL-LSILDSQTWLAQ--------
---------------------------------------------------ATDHTFLHK
CHYHHGDHPSYAKPQLPLPIFTVQHYAGTVTYQVHKFINRNRDHLDSAMVEMLGQSQLQL
VCSLFQE-----------AEP-QAGREEGKPTLASRFQQSLGGLLARLGR-SHIYVIHCL
NPTPGKLPGLFNVGHMAEQLLQAGILEVIGTRSAHFPVRVPFQLFLT-RFRALGSGRQEA
LSDQERCGAILSQVLGAESPVYHLGNTQVPILLQEQGWQQLEQLLGQQRSQALLTLHRGL
RACITRQRLH--L--P-ASASRV-LGLK--------------------------------
------AKRYLQRKSALGQLNTILLVARPLLQ--RRQRRQV-----M-------------
-GGGDLGRLEIPAQLAALLETAEGHQAILAGSITESLPPGVPVRPNLTLPPDIDQFPFSS
FVSSSFRVKLLPGQPPKPQRKPVSKKNQTNKQTNKQTNKK--DEGNFPGQKSWQEQT

PF00784 // ENSGT00920000148963_7_Domain_3 (1798, 1903)

MGT
YLIRKAQHRPGLRDELFSQLVAQLWHNPDEQQSQRGWALMAALLSSFPPTPALQKPLLKF
VSDQGSRGMAALCQHKLLGALEQTQLAPMASRTHPPTQLEWK

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGLRQGRM--------VL
DVFTFNEESYFAEVESWTTGEQLAGRILHSRGLEAPPRGWSVSLHSGDAWQDLAGCDFVL
DLIGRTEDLGD----PAGSHNYPITPLGLA-------------------ENIPPAPGVQA
PSLPPGFPPGPAPTL-PSS-GPPG---------------------EARK-PG-NMDGFL-
--DYIFEPVLSSGFSDLEHSRALSSRMKGGGSIGPTQ-PGYPM-GEASQAPQQGWSES--
-----------PQATEMGALATMMVPPQP------QPLLPSLDSRQLAVQQQNFINQQAM
ILAQQMTTQAMSMSLEQQNQRRQ-NQAQA----------------SGAPSQTPPPA----
PKKPP--------ASQEKPES--DPEPL--------------DGDTPE-EATGRPQRPRS
FQQKRDYFQKM---GQE----PIRVKTVKPPAKVQIPQEETDENEDEEEE----------
--E---DTAESS-PPPPPPVVK-KPLKQTK------------PNSAKDG-AEPAEEEKPT
PGRAPKVK--SSTPQSPPPSR-APTVSSSNSTP-QRPQPSREIRNIIRMYQSRP--GPVP
V-----------PVQPSR--PVKPFQKKNDPKDEALAKL-----------G-----ISGT
HLPPSAM--SPNLGKNSPPAVAPRPKARPQLEPSLSIQEKQGPLRDLFGPCSPNPSTTPA
PPSP----PPLPLSLPEEPKAHSVGSHALTEPMEDLGISTKLLVPSGSVCFSYASAPWKL
FLRKEVFYPRENFSHPYCLNLLCQQIIQDTFTESCIRISQSERQKMKDLLGDLEVGLDSL
DSTEDSIKKRIVVAARDNWANYFSRIFPVSGESGSDIQMLGVSHRGLRL---LKVTRDPS
------FHLD--RLKTLCSYSFAEVLAVGCSSSSTLELSLKNEQLTLHTAQARAIKAMVE
QFLNE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FHRGDLIKLLPAGILEPDWQGRRT---
------------IIWE-----CLLGWQFGSVGGHSGLFPADVVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3156)

PAAAPDFSFSLGQRNS
WHRKSKTG--------P-AHERPTHPRSQ---EPSEDSEATSFAAYSLFSADSHNYTMQE
FALRYFRKPQTL-------LAQAGRGANDKAEVSLVQYTK----DPIQESLLSLSNEDIN
RKAVAGFKALMQFMGDQPKPRGKDELDLLYELLTL

PF00784 // ENSGT00920000148963_7_Domain_5 (3156, 3253)

CR--EDLRDEMYCQVIKQVTGHPQP
NHCVLGWNVLSLFTGFFAPSTTLMPYVTKFLQDSS-----PSQELARSSQENLQRTVKYG
GRHKLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRSLLIHLPGGVDYRTNVQTFTVAGEVLEELCGQMGITDSQ
EVQEFALFLIKG----EGELVRPLSPHEYLNSAVTD-KDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPTY
TETHYGQVLRDYLQGKLMISAQ--ADAQLARLAALQHLRKASK-SLPSAQPLLLVYIPKP
LQ----QQVNIANIRSLVGQELRQMQGYSAQRAQIDFIE---------------------
------------STTQLPLFGYTVYVVLRVSKLSLPGPILLGLNRQHLVLMDSSS-----
---QRLCCSIPLRDLQRLHLLSPLEDNGAPGLELNYGSADNPHTIWLELPQAQELKHTIV
FLLE-DSMSST---QWPGLS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------PALW-------PCPAGP-----RPTAQPLWLQ----APIQKSLISFSDEDTN
RQAVESFQALMQFMGDLSKPRGKNELD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYGLLKLCQEKEDLRDEVYCQAIKQVTGHPRP
KLCTRGWRFLSLLTGCVPPSNTLMPYVTKFLQDWG-----PHQELAQSSQEHLQRTVKYG
GRRRLPSPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3355)

AFLKGQVVHLVLIHLPGGVDYKTNIRTFTVAAEVLEELCRQMGITDPQ
EVQEFALFLIKG----DSELVRPLWPQEYLNSVLGG-PDVSLHSRRLGWETRLH

PF00373 // ENSGT00920000148963_7_Domain_6 (3355, 3505)

FDNPTY
ISTHYSQVLRDYLQGKLGLSPQ--EDTRLARLAALQQLSRNKE-EPP-SEQDLLAYLPRK
PQWQQQWQMNVATVKSLMGRELRQLQGYSSQEAQISFIK---------------------
------------AVSELPLFGFTVYPVQRVSSPALPSPGLLGLNRQHLVLVDPSS-----
---QELCCSIALRDLQRLHLLSPLEPEGSPGLELNYGSADNPQTIWFELPQVGGLRVP--
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------I

PF00063 // ENSGT00920000148963_7_Domain_0 (790, 1534)

EDLTRLQEVSESSVLLCLKKRFHCNLIYTYIGQILISVNPFKDLSIYSEDV
ATEYQQGTLSKNAPHIFAIAERAYT-LSQSSGQEQYVLISGHSGSGKTEAAKAIVQYLTM
LYQGSDSHRIRQPCNVLPILESFGNARTILNDNSSRFGKLLNVHLLHGIVVGTSISQYLL
EKSRVVFQAQGERNYHVFYELLAGLPVQQKEELYLQEAESYFYLNQ-GRACEVLGKEDSQ
DFLVLVQALEGISLSEDHLSSTWAVLAAVLQLGNICFTSCEKESFEHAAVASATEIQIVA
SLLRVSAELLQRAVT----HRVTVTSYDRIFTPLSVEGAIDAR-DSIAKALY-YLLFEWL
LLRINEWLAPWESD---CAVGIVDIHGFEDLGV--NSLEQLCINFANEHLQWFFSQTVIA
QEEEEYSQEQLTWIPMSK----MYSQSCLDFLTAKPHGI-LCILDDQTSLPQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGNSPWYTKPKLPLPEFTVQHYAGPVTYQVHKFLSKNRDQLKPEVLDIFSQSRLKV
VSYIFQRAKAACGQRRELGGK---GLRPQTSTLVSKFQQSLQELTAKLPR-SHSFFIRCI
TPNPRKLSNIFDVEYVNCQLRHSGILEAIHIQKEGFPVRLSFQSFLA-RYGLLAGGSPSS
LQQREGCAAVLAHVLGSPSDLYQMGVTKV--FL

ENSGT00920000148963_7_Linker_0_2 (1534, 1575)

KEEARQLLERLWQQRQSWAVVTLQRKF
RRLLQQRRLRLLQE

PF00612 // ENSGT00920000148963_7_Domain_2 (1575, 1631)

KVTVIQAHF-RGYQA-------------------------------
------RKRY

ENSGT00920000148963_7_Linker_2_3 (1631, 1797)

KRLKKTFVQFKTMILVSRPLIQWRRRCQKEPSHTE---------------
-ISQDVGLLEIPAELAALLHFVEGHRAQA-NQITETQPPEVKVKDGLSLPPTINSYPFSS
FIKSHFQKPDFPAPGQP-LQHPLTHLDAEHQESALEINKLILRFIGDKSLRGWQEV

PF00784 // ENSGT00920000148963_7_Domain_3 (1797, 1903)

LLGN
YIAGRGLSDAALRDEIFSQVVSQTWRNPDTENSQRGWVLMATLLSCFGPSPALEKPLLKF
VSDHGLEGYSAVCQRKMLTAAQSADTQPAPSRAYPPTQLEWT

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

ANQRRGKM--------VL
DVHTFNEEKFSAEVESWMTGEQYAACILSARGCDKKTRGWSVSMFTGSTWQDLLGCDFVL
DLIGEMEETSNFSSSSQAPTEYPITPERDRSIL-----------QASDLDMIPPAPDIQA
PAFPPPSLPPELIGLHPGLWLTLGRARWAPARAGLLSAPDSRFREDMRT-PV-GLDHYV-
--DDLFSPVLHQGSREMENREILTRRMKGGGKIGPTQRGIFPS-A---------------
---------------------AMVM---------PQPMVPAVDPSQLAAQQQAFINQQAM
LMAQQMTLQALSISQQQQQELQK-QQKSLENSRP----------RVSSPVRASAPATLPK
PKNPF--------SNQAAATT--SNS----------------------------------
---------------------------PEPPGN--LPAEERVLPE---------------
----------------------------DG-------------REKR--NVRPLPV----
-----------------------SIRGKEREGPESRPAPSHEIGNIIKMYQSRPAPEPLP
L-------------QPVR-RVSKPFIKKNDPKDEALAKL-----------GMMK------
--------SSPQPPQSQEG--------------AQECRER---LAQIFLLLAAISCARN-
--------------CPLSP--------GRSLVDGDDGIKTQLYKLTTSVSFSYVDPAWKI
FLRKEVFYPKENFSHPYCLNLLCEQIIRDTFSESCFRISREEKRKMKDLLTEFQVGSNAQ
SIQEEGIKKRIVVAARDNWANYFSRLFPVRGEKGSDVQILGVSHRGMRL---LKVEKASG
------YHPE--HLKILRSYCFADVLSVEMTGSNSLEFSLKTEQLILHSAKAPCIKAMVE
LFMQE---LRQDSN

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2984)

YVV-ALRSYIVDDKSLLS-FKKGDLIELLPVQGVEPGKPGVSDALL
CQQRASVLVSLGCPVPDCSSAAFAGWQFGSCGGRCGLFPTSLVQLAPAPDYLSSSMDRRA
EQRRSTRA----------------SPESRNTSREV---SSPGRS---SQ-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------DLEAPSLHPS--AGSLSTYSHNYSMQE
FALRFFREPRTL-------LHSTDGDAKVKATDSLVQYTK----VPIQESLISFSDEDKN
KQAVESFRALMQFMGDQSKPRG

PF00784 // ENSGT00920000148963_7_Domain_5 (3143, 3255)

KDEVELLYELLKLCRE-ESLRDEIYCQVIKQVTEHPQP
EHCTRGWKFLSLLTGFFPPSTTLMPYVTKFLQGAG-----LSQELACSSQEHLQRTVKYG
GRQRLPMPGEIKAFLKGQEVHMLLIHLPGGVDYRTNIQMFTVAAEVLEELCSHMGVADPQ
EVQEFALFLIRG----EGELVRPLRPFEYLNSVMVD-QDLSLHSWRLGWETPLHFDHPTY
ICIHYSQVLWDYLQGKLLVSAQ--ADAQLAHLAALQHLSRNTK-DPP-TERDLLLYVPKQ
LQ----RQLNMATIKRLMDQELRQLQRHSLQDAQISFIE---------------------
------------AVSQLPLFGYTVYVVLRVSQLALPGPGLLGLNRQHLILMDSSS-----
---QKLYCSVALHEIQRLRLLSPREEGGAPGLELNYGSVHSPQTIWFELPQAQELQQTIA
FLLDSST-ST---P-------

MGRNQRKAPQRLERPGRPASGEQESGSASADG-ARSRERRSDRGQADRARPASEPATAGG
QGTPGGRRKPTAEGNGGCRRPGAGLSPKAQERQSNAQRQGRGPRGGR------GGRLEEG
SLSGGEEL----GGRRRRKRKDKGPSARRGRRTPRSLNGDTSGGDGGSSCPDSETREAQE
SGSQRGRARELRPTPEPTDMGSEGTKTGPESALEP----S-SDGLDSDWPHADTRGREGS
SGTGPLGASEHSGGDSDSSPLGTGPGRGARAAM--ASRT--------------------F
EDSSRAPRDTGPAKDASDNRAQ-----RGAEPETMQASTARAPRHQVGKAVGRVPAAAGE
-------------------APLAALLVVRRLLARPPPGDASQAVGPRRAGLKERLLSVAR
ALGLLRWLRRRLRLRRRPPEGEGQGTGPRASEGWGRRKADERRGHGRGSEGRGRGKADEG
RGHERGYEGRGRGKADEGQD---------RGRADEG---------RGHERGDEGRDHQRG
YEGWGRERPGLRHRLALHLA-GLAGLGGMPRAPLGGRS--PQVPTSPVPGD-RFDQEDET
PDPKFAVVFPRIHRAGRASSSRRSEEA--SADAPTGEGRGWPRAGAGGHSEGEGCRASGE
GVSGLRRGSLLAPTAPNGPSLDESGSSSEAELETLNDEPPVHWAQSSGSHEGPRLGA-AV
LLPRLAFETRLQQEGDPGLRGSLRELWEPEDEDEAVLGRDLELSLWPGLEAPPFPGAKGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQNTGQDPCILLRGHSGSGKTEAAKKIMQFLSS
LEQDQTRNRECQVEDVLPILSSFGHAKTILNANASRFGQVFCLYLEQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLLKALQGLGLCPEELNAVWAVLAAILQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPVESAVDAR-DALAKALY-SRLFHRL
LRRTNARLAPPGEGGSIGTVTVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE-------------------PPRESCLDVLVDQPHSL-LSILDTQTWLSQTE------
-----------------------FGSCCPGWSA-----MVQFRLTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALEDLIAQLGR-SHVYFIQCL
TPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFEAFLA-SFRALGSEGQED
VSDREKCGAVLSQVLGAESPLYHLGATKV--LLQEQGWQRLEELPDQQRSQVLVDLHHSF
HTCISRQH----V--LPWMQARM-RGFQARSAGVGARAEVGGPVFTHSSNSCWLTVCLIY
-PWARCWKRYLRRRAALGQLNTILLVAQPLLR--RRQRLQLG----HWQGWHSSERALER
VPSMELGRLEIPAELAVMLKTAESHRDALAGSITECLPPEVPARPSLTLPADVDLFPFSS
FVAIGFQEPSLPRPGQP-LAKPLTPLDGENPQRALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
MSDQAPRGMAALCQHKLLGALEQSQLASGATRAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDAWQDLAGCDFVL
DLISQTEDLGD----PARPCSYPITPLGSA-------------------EAIPLAPGIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVISSGLSDLEQSWALSSRMKGGGAIGPTQQ-GYPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP--------PLPSLDAGQLAVQQQNFIQQQAL
ILAQQMTAQAMSLSLEQQTQQRQ--RQ---------------ARASEAASQASPSAVTSK
PRKPP--------TPPEKPQR--DLGSEGG----------CLR-ETSE-EAEDRPYRPKS
FQQKRNYFQKM---GQP----QITVRTMKPPAKVHIPQGEAQEEEEEQEEEEEQEEQEE-
QKEQEVETRAVP-SPAPPPIVK-KPLKQGG------------AKAPKEAEAEPAKETSAA
KGRG----------QGPAQGR-RTMVRSSDSKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQP--SRPPKTFLKKIDPKDEALAKL-----------G-----INGA
HSSPLML--SPSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPIAQTPP-
---PPPAP---PLPLPEDPGTLSAERRCLTQPVEDQGVSTQLLAPSGSVCFSYTGTPWKL
FLRKEVFYPRENFSHPYYLRLLCEQILRDTFSESCIRISQNERRKMKDLLGGLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRALAHDPGLEVGAGGK
------VTPV--HARS--LRSFAEVLGVECRGSSTLELSLKSEQLVLHTARARAIEALVE
LFLNE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
WHKGQLSNGEPGLARWDRASERPAHPWSQAHSDDSEATSLSSV-AYAFL-PDSHSYTMQE
FALRYFRRSQAFTLLRATGLGQTDGGAAGKDTDSLVQYTK----APIQESLLSLSD-DVS
KLAVASFLALMQFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQQ-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGFFPPSTGLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRRMPPPGEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAAEVQEELCRQMGITEPQ
EVQEFALFLVKE----KSQLVRPLQPAEYLNSVVVD-QDVSLHSRRLHWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3459)

HFDNSTY
ISTHYSQVLWDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NTP-SEQDLLAYVPKQ
LQ----QQVNTASIKNLMGQELRRLEGHSPQEAQISFIADLGDQAEQ---V----PGPQQ
SDFLPAPSPPAEAMSQLPLFGYTVYGVLRVSMQALSGPTLLGLNRQHLILMDPSS-----
---QSLYCRIALKSLQRLHLLSPLEEKGPPGLEVNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SCT---EWPSIN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

PF00063 // ENSGT00920000148963_7_Domain_0 (800, 1534)

ESSVLLCLKKRFHCNLIYTYIGQILISVNPFKDLRIYSEDV
ATMYQKGTLSKNAPHIFAIAEMAYT-LSQSSGQEQCVLISGHSGSGKTEAAKAIVQYLTT
LYQGSDSHRIRQPCSVLPILESFGNARTILNDNSSRFGKLLDIHLRHGIVVGTSISQYLL
EKSRVVFQAHGERNYHVFYELLAGLPVEQKEEMYLQEAESYFYLNQ-GRACEVLGKEDSQ
DFLVLVQALEGISLSDDQLNSTWAVLAAILQLGNICFTSYEKESFEHAAIASDTEIQIVA
NLLRVSAELLQSAVT----HRVTVTSYDRIFTPLSVEGAIDAR-DSIAKALY-YLLFEWL
LLRINEWLAPWESD---CAVGIVDIHGFEDLGV--NSLEQLCINFANEHLQWFFCQTVIA
QEEEEYSQEQLAWIPISK----MCSELCLDFLTAKPHGI-LCILDDQTSLIQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGNSPWYTKPKLPLPEFTVQHYAGPVTYQVHKFLNKNRDQLRPEVLDIFSQSRLKV
VSHIFQRAKAAYSQQRELGGR-GRGLRPQASTLVSKFQQSLQDLTAKLRG-SHAFFIRCI
TPNPRKLSNVFDVEYVNCQLRHSGILEAIHILKEGFPVHLPFQSFLA-RYGLLAGSRPSS
LQQREGCAAVLAHVLGNPSDLYQIGVTKV--FL

ENSGT00920000148963_7_Linker_0_2 (1534, 1576)

KEKGRQLLERRWLQRQSWAVVTLQRKF
RRLLQRRR---LQEK

PF00612 // ENSGT00920000148963_7_Domain_2 (1576, 1631)

VTLIQAHF-RGYQA-------------------------------
------RKRY

ENSGT00920000148963_7_Linker_2_3 (1631, 1797)

RRLKKTLVQFKSMIIISRPLIQRRKRCQVTTEQGERPQMMWRQKSLLWLR
CSIPDVGLLEIPAELADLLHFVEGEKSSSFPPFPALKPPEVKVKDDLSLPPTINSYPFSS
FIKSHFQKPDFPAPGQP-LQHPLTHLDAEHQESALEINKLILRFIGDQSLRGWQEV

PF00784 // ENSGT00920000148963_7_Domain_3 (1797, 1904)

LLGN
YIAGRGLGDAALRNEIFSQVVAQTWRNPDTEHSQRGWVLMATLLSCFGPSPALEKPLLKF
VSDYGMEGYSAVCQRKMLTAAQ------APSRAYPPTQLEWTANQRRGKM--------VL
DVHTFNGNSFSAEVESWMTGEQYAAWILSARGCDKKTRGWSVSMFTGNTWQDLLGCDFVL
DLIGEME-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------EECYSAEVESWTTGEQLAGWILQSKGLEAPPRGWSMSLHSRDTWQDLAGCDFVL
DLIGQTEDLGD----PAGPCSYPISPLGS-------------------AEAIPPAPTVQA
PSLPPGPPPGPAPTL-PSR-SHTG---------------------KTSK-AG-SLDGFL-
--EHLFEPVLSPGLRDLEQGWDLSGRMKGGGAMGPMQQ-GYPM-VYPGMMQMPGYQPA--
-M-MPAPIPMMPAMGAGPAMPTMVVPPQPQ----PQPLLPSLDARQLAVQQQNFINQQAL
ILAQQMTTQAMTLSLE-QQTQQRQRQHQQQ------------AEALRAASQTPPIAITPK
PKKPP--------APREEPER--ELESGGT----------YLREGISE-EAEDRSLHPRS
FQQKRDYFQKM---GQQ----QIKVKALKPPAKVQIPQREEQEEQEEEPRTGA---A---
--------AGVVLSPPPPPAVK-KRSKQGE------------TKAAKEAEAEPAGEAGSG
-HDQ-----------ERTQGR-ALMVQSLVHTS-QRPEPSKEIRNIIRMYQSRP--GPVP
V-----------PVQPSR-RPLKTFPKKNDPKDEALAKL-----------G-----IHGA
HSSPSTM--SPSPGKSPPPTVAPRPKALPQPGPSSSIKEKQGPLQDLFGKNMPTTRAP--
-----QPPPAPPLSLPEDPGAPSAEPRGLMEPMGDQSTSTQLLVPSASVSFSYTSAPWKL
FLRKEVFYPRENFSHPYCLQLLCEQILRDTFAESCIRISQDERRKMKDLLRDLEVGLDSL
ATAEDNVKKRIVVAARDKWANYFSRIFPALGESGSDVQLLGVSHRGLRL---LKVSHGPS
------FHPD--QLKTLCSYSFSEVLGVKCPGGSTLELSLKNEQLILHSARATAIKTMVE
LFLNE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDCSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSAGGRSGLFPTDMVQPAAAPDFSFSSEQRSQ
-HKSHLQLGEPGLAQWDRALE---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------TSEPSSITSVPAGDHYTMMD
FAAVYFREAQLM-------TELKGTPAEKKTIADMVQYTK----VPIQESLLWYSDSELN
ELATKNFKTLMRFMGDQPKLKN

PF00784 // ENSGT00920000148963_7_Domain_5 (3143, 3255)

QDDAQCAYEILQLCKEKENLHDEVYCQVIKQVTFNPNQ
ESVLRGWLLLNLLTGFFLPSNTLMPYATKFLQQASSDPSSTHHEIARICQSNLRKNFMYG
GRRHLPFPVEMEALLKGRSTRRLEVLMFGGVEYVTRIRTFTVAKELLQEICEQMGAGEQE
EMQEFALFAIRS----TNKIVRPIRMEEYLHDYLLEDILVTVNLRRLTWKTPLHFEDKIY
TDIHYGQIQWDYLTGKILVSYSKELEMQLGVLVMLQHWAKTEQESSAPSREDLKEYIPKS
LQ----SRISTETLQNHLDRLLRTMQPLRPVDAKIQFIE---------------------
------------HVMKQPLFGYNIFLVEKVSNSTIPVPCYFGVNKEQIIVVDSIT-----
---QELCHIIPLKELQRMRILRPTSEQGLPGIELNYGSAASPKTLWIELSQAKEMYHTTV
AIL------------------

MGRSKGKAPQRRPRPGRPASAEPESGSASADC-APSPDRRPARSKARKNKPATEHEATGG
KGTAGGQRKHTGEGNHRCRSAETGTSQETQERQGSSQRLRHGPTESRDSGDSCGEHTEEQ
GIPREEERTGKRGRRRR--GKDRGPLTRRGHGETPGRDGDTSGGDGGSSCLDSEAREAQD
SSSQGGGAPERPPKMEPSDPSSEGAPIRGPSSTQVQGKCPGSNHPGSEGHALELQSKEGS
SETGPQRASDDSRTDTDSSPGWAGHRHLPQKIP--ETSSGIPESQEIELGREAAAS--SV
PKGSQSPQDSSAILDTSDVGAQPKAELLGTEPETAG--APGAQLLQVGEVTRKALVVAGE
SDAGARERSGAGDPGPRDRTPLAALVVLRRLRPRPPAGASPQFAGGIRVGLKARLQRVAR
ALGFLRWLRLRVERR----RTEARAASPREC-----------------------------
----------------------------------------------------EERGRERA
LEARG-RVPGPRRWLALRLACRLVGLRGTPRALPDGGPSPPQALSSSISND-ASAIEDPA
PDPKFAVVFPRIHNAGKESGSSSS-RT--STGAPTAG-A-------AEDR--EEQEANGE
GVVRACQVPSFFPSARNGTPPNEN--RSEAEPETLEAKTGVHWAQDSNPSEDPELGA-DT
LLPQLTLETRLR-QNSP--CRSPREQWEPEDDTEAALERDLELNLQRNLEMPPFLGAKTG
SLPESLEDI

PF00063 // ENSGT00920000148963_7_Domain_0 (790, 1533)

EDLARLRLVCDSSVLLCLKKRFHLGRVYTFGGPLLLALNPHRSLPLFSSEV
LASYHPRKAPNTTPHIFAIGAAAYS-LSQSTGQDSCILLGGHSGSGKTEGAKKILEFLSS
LGQKPMEANLAQLEDILPVLGSFGHAKTILNANASRFGQEIRLCLQQGLIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDPTEREQLSLQGPEVYYYLNQ-GGACRLQGKEDAQ
DFTELMKALRGLGLCTEELTAVWAVLATVLHLGNICFSSSERESQEVAAVSSWAEIHLAA
RLLQVPPERLEGAVT----KRVMDTPYGPVSRPLPVEGAIDAR-DALAKTLY-TRLFTWL
LKHINARLSPPREADSVATIAVVDAFGFEALRV--NGLEQLCSNLASERLQLFSSQKLLA
QEEEACQQELLKWVPIPQ---P-PRQSCLDLLVGQPHSL-LSILDTQTWLSQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGEHPSYAKPQLPLPIFTVRHYAGTVTYQVHKFINRNRGHLDPAVLEMLRQSQLQL
MGSLFQE-----------AEP-QVGTEQNKPTLASRFQQSLGDLLARLGR-GHVYVIHCL
NPTPGKIPGLLDVGHVAEQLRQAGILEIIGTRSTHFPVRVSFQVFLA-RFHALGSGRQKA
ASDQERCGAVLSEVLGAESPLYHLGVTQV--LLQEQGWQQLEQLWAQRRSQALLTLHRGL
RACITRQRLR--L--LPRMQARV-RGLQA-------------------------------
------RKRYLQRRSALGQLNTILLVARPLLR--RRQKLR-------CAPGPHSGEPWGK
VSNMDLGRLEIPAQLATLLERAEGHQALLTGSITESLPPEVPARPSLTLPPDIDQFPFSS
FVSTSFQKPFLPRPGQP-LDEPLTRLDGENPQQALEINRVMLRLLGEGSLQSWQEQTMG

PF00784 // ENSGT00920000148963_7_Domain_3 (1800, 1903)

T
FLVQQAQRRPGLRDELFSQLVAQLWRNPDEQQNQRGWALMVILLSSFAPTPALEKPLLKF
VSDQAPSGMAALCQHKLLGALEQTPLAPMASRSHPPTQLEWK

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGLRRGRM--------AL
DVFTFNEESYSAEVESWTTGEQFAGWILQSRGLEAPPRGWSVSLHSGDAWRDLPGCDFVL
DLIGQTEDLGD----PAGPHNYPIAPLGLA-------------------ESIPPAPGVQA
PSLPPGLPPGPAPIL-ASS-RPPG---------------------KASK-PG-NLDGFV-
--DHLFEPALAPGFSDLEQGWALSRRMKGGGSVGPTQ-QGYPM-VYPGMVQAPSYQPAM-
---IPAPMPVMPAMGAVPTMPAMMVPPQP------QPLVPSLDSRQLALQQQNFINQQAM
ILAQQMTTQAMSLSLEQQNQRHQ-HQAQT----------------SGATSQPPPSTTAPK
TKKPP--------APQEKPES--NLEPSGV----------CLREDTPE-EAESRPQRPKS
FQQKRDYFQKM---GQE----PIRVKTVKPPAKVQIPQEEMEETE------EEE------
-EE---TAELSP-PPPPPPVVK-KPLKPSR------------PKAVKEDEAEPAQEEVPT
QGKDPPVLSSNSAPQHPKPSR-VPPVQSSNSAP-PRPQPSREIRNIIRMYQSRP--GPVA
V-----------PVQPTR--PIKTFQKKNDPKDEALAKL-----------G-----INGV
HLPL-ST--SPNQGKSSPPAVVPRPKARPRLEPSLSIQEKQGPLRDLFGPCSPNPPTAPV
PPPP----PALPPPLSGEPKTPLVESHALTEPMEDKNISTKLLVPSGSVCFSYANAPWKL
FLRKEVFYPRENFSHPYCLSLLCQQILRDTFTESCTRISQDERHKMKGLLGDLEVSLETL
DIVEDSIKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTQSPS
------FHLD--QLKTLCSYSYAEVLTVQCRGRSTLELSLKNEQLILHTAWARAIKAMVN
LFLSE---LRKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDNSLLS-FHRGDLIRLLPVTALEP----------
------------------------GWQFGSAGGRSGLFPDDLVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3156)

PAAAPDLSFSLGKRNS
WQRKSKLG--------P-AQERPTHPRKQ---EPSEDSEATSFTTYSSLSADPHNYTMQE
FALRYFRKPHTW-------LTQMSRDTKEKAAINLIQYTK----DPIQESLTSFCNGDTN
SKAVAGFKALMQFMGDQPKPRGKDELTLLYELLKL

PF00784 // ENSGT00920000148963_7_Domain_5 (3156, 3253)

CQ--DDLRDEMYCQVIKQVTGHPQP
KHCALGWSVLSLFTGFFAPSTTLMPYVTKFLQDSS-----PSEELARRSQENLQRTVKYG
GRQQLPLPGEMN

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRLLLIHLPGGVDYRTNSQTFTVAGEVLEELCGQMGITDLE
EVQEFALFLIKG----EGELVRPLSPHEYINNVVTD-QDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHSTY
TETHYGQVLRDYLQGKLIVSTQ--AEALLAQLAAFQHFDKTGT-SCPPSEQELLSYIPKP
LQ----WQVNTANIKSLVTQELRQMQGYSKQRAQIGFIE---------------------
------------STAQLPLFGYTVYVVLRVSKLALPGPGLLGLNRQHLVLMDPSS-----
---QELCCSVMLKDLKQLHLLSPLQEDGPPGLELNYGPVDNPQTIWLELPQAQELQHTII
FLLGS---MST---QWPGLL-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------LDQTREGAGDMATASLVQYTK----VPIQESLISFSDEDTN
KQAVESFRALMQFMGDQSKPRGRE

PF00784 // ENSGT00920000148963_7_Domain_5 (3145, 3254)

ELELLYQLLKLCRE-ENLRDEIYCQVIKQVTGHPQP
EHCARGWSFLSLLTGCLPPSTTLMPYVTKFLQDSS-----QSQELARSSREHLQRTVKYG
GRQRLPTPGEMHA

ENSGT00920000148963_7_Linker_5_6 (3254, 3354)

FLKGQTVRLLLIHLPGGVDYKTNVRTFTVAAEVLEELCGQMGITDPQ
EVQEFALFLIKG----ESDLVRPLWPHEYLNSVVVD-QDVSVHSRRLSWESPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDNSVY
TSTHYNQVLRDYLQGKLPVSAQ--AEVHLAQLAALQHLGRDTK-EPP-SEQELLAYMPKP
LQ----QQVNTATIKRLLDQELRRLPPHSPQEAQISFVK---------------------
------------AMSQLLLFGCTTYVVLRVSELALPGPILLGLNRQHLVLMDPSS-----
---QKLYHSVMLRDVQRLHLLSPLEADGLPGLELNYGSVDSPQTIWFELPQVGE------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------QAHSDDS--------VAYISLSTDSHDYTMQE
FALYHFRKPQTL-------LDHTGRDAKEKAMASLVQYTK----APIQESLLRLSEEDAN
TQAVESFQVLMQFMGDQSKPRG

PF00784 // ENSGT00920000148963_7_Domain_5 (3143, 3255)

KDEMELLYDLLRLCREKENLRDEIYCQVIKQVTGHPQP
EHCARGWNFLSLLTGFFPPSATLMPYVAKFLQDSG-----PSQELAQSSQEHLQRTVKYG
GRLRLPSPGETQALLKGQGVRSLLIHLPGGMDYKTNIRTFTVAAEVLEEVCQQMGIMDPQ
EVQEFALFLIKR----EGELVRPLWPHEYLNSV-LD-QDISLHSRRLSWETPLHFDNPTY
ITTHYLQVLRDYLQGKLLVSPK--ASAQLARLAALQHRSKAQE-DHL-LERDLWTYLPKP
VQ----SQVNMSAIRNLTDQELRQLPVCSPQEAQISFLE---------------------
------------AVSQLPLFGYTVYVVLRVSQLALSGPSLLGLNRQHLILMDPCS-----
---QKRCHSITLKDLHRLHLLSPLESKGPPGLELNYGSAESPQTIWFELPKAQELKDTIA
FLLDS----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------DSEATSLQSSTVYTSLSTDSHNYTMQE
FALHYFRKPLTL-------LDLTGGGTRAKAMASLVQWSKVRG-APIQESLIRLSDENMS
KRAVVGFEALMQFMGDQSKPRGKDEMDLLY

PF00784 // ENSGT00920000148963_7_Domain_5 (3151, 3253)

ELLKLCQG-EDLRDEMYCQVIKQVTGHPQP
EHCARGWSLLSLFTGFFPPSTTLMPYVTKFLQDSG-----PSQELARRSQQHLQHTIKYG
GRQRLPQPGEMR

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRQLLIHLPGGVDYRTNLKTFSVAGEVLEEMCGKMGITDPQ
EIQEFALFLIK-----GGELVRPLWPHEYLNSVVVG-QDTSLHSQRLSWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPIY
IGTHYGQVLRDYLQGKLMAHAQ--ADAQLAQLAALQHLGRASK-SPP-SEQDLLGYIPKT
LQ----WQVNMATIESLMGQELRQLQGHSSQEAKISFIE---------------------
------------ATRQLPLFGYNVYVVLRVSNLVLPGPVFLGLNRQHLVLMDPTS-----
---QKMCCSIALKDLQRAHLLSPLKVNGPPGLELNYGLADSPQTIWLELPQAQELLRTII
FLLD-GSVSSTQP-RWPGLI-

MGRSKGKAPHRRPRPGRPASAELESGSASADC-APSPDRRPARSKARKNKPATEHEATGG
KGTAGGQRKHTGEGNHRCRT-----SQETQERQSSSQRLRHGPTESRDSGDSCGEHTEEQ
GIPREEVRTGKRGRRRR--GKDRGPLTRRGHGETPGRDGDTSGGDGGSSCLDSEAREAQD
SSSQGGGAPERPPKMEPSDPRSEGAPIRGPSSTQVQGKCPGSNHPGSEGHALELQSKEGS
SGTGPQRASDDSRTDTDSSPGWAGHRHLPQKIP--GTSSGIPESQEIELGREAAAS--SV
PRGSQSPQDSSAIVDTSDVGAQPKAELLGTEPETAG--APGAQLLQVGEVTRKALVVAGE
SDAGARERSRAGDPGPRDRTPLAALVVLRRLRPRPPAGASPQFAGGIRVGLKARLQRVAR
ALGFLRWLRLRVERR----RTEARAASPREC-----------------------------
----------------------------------------------------KERGRERA
LEARG-RVPGPRRWLALRLACRLVGLRGTPRALPGGGPSPPQALSSSVSND-ASAIEDPA
PDPKFAVVFPRIHKARKESGSSSS-GT--SAGAPTAG-A-------AEDR--EEQEANGE
GVARACQVPSFFPSARNGTPPNEN--RSQAEPETLEAKTGVHWAQDSNPSEDPELGA-DT
LLPQLTLETRLR-QNSP--CRSPRERWEPEDDTEAALERDLELSLQRNLEMPPFLGAKTG
SLPESLEDI

PF00063 // ENSGT00920000148963_7_Domain_0 (790, 1533)

EDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPLLLALNPHRSLPLFSSEV
LASYHPRKAPNTTPHIFAIGAAAYS-LSQSTGQDSCILLGGHSGSGKTEGAKKILEFLSS
LGQKPMEANLAQLEDILPVLGSFGHAKTILNANASRFGQEIRLCLQQGLIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDPTEREQLSLQGPEAYYYLNQ-GGACRLQGKEDAQ
DFKELMKALRGLGLCAEELTAVWAVLATILHLGNICFSSSERESQEVAAVSSWAEIHLAA
RLLQVPPERLEGAVT----KRVMDTPYGPVSRPLPVEGAIDAR-DALAKTLY-TRLFTWL
LKHINARLSPPREADSVATIAVVDAFGFEALRV--NGLEQLCSNLASERLQLFSSQKLLA
QEEEVCQQELLKWVPIPQ---P-PRQSCLDLLVGQPHSL-LNILDTQTWLSQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGDHPSYAKPQLPLPIFTVRHYAGTVTYQVHKFINRNRGHLDPAVLEMLRQSQLQL
MGSLFQE-----------AEP-QAGTEQNKPTLASRFQQTLGDLLARLGR-GHVYVIHCL
NPTPGKIPGLLDVGHVAEQLRQAGILEIIGTRSTHFPVRVSFQVFLA-RFHALGSGRQKA
ASDQERCGAILSEVLGAESPLYHLGVTQV--LLQEQGWQQLEQLWAQRRSQALLTLHRGL
RACITRQRLR--L--LPRMQARV-RGLQA-------------------------------
------RKRYLQRRSALGQLNTILLVARPLLR--RRQKLR-------CAPGPHSGEPWGK
VSNMDLGRLEIPAQLATLLERAEGHQALLTGSITESLPPEVPARPSLTLPPDIDQFPFSS
FVSTSFQKPFLPRPGQP-LDEPLTRLDGENPQQALEINRVMLRLLGEGSLQSWQEQTMG

PF00784 // ENSGT00920000148963_7_Domain_3 (1800, 1903)

T
FLVQQAQRRPGLRDELFSQLVAQLWRNPDEQQNQRGWALMVILLSSFAPTPALEKPLLKF
VSDQAPSGMAALCQHKLLGALEQTPLAPMASRSHPPTQLEWK

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGLRRGRM--------AL
DVFTFNEESYSAEVESWTTGEQFAGWILQSRGLEAPPRGWSVSLHSGDAWRDLPGCDFVL
DLIGQTEDLGD----PAGPHNYPITPLGLA-------------------ESIPPAPGVQA
PSLPPGLPPGPAPIL-ASS-RPPG---------------------EASK-PE-NLDGFV-
--DHLFEPALAPGFSDLEQGWALSRRMKGGGSVGPTQ-QGYPM-VYPGMVQAPSYQPAM-
---IPAPMPVMPAMGAVPTMPAMMVPPQP------QPLVPSLDSRQLALQQQNFINQQAM
ILAQQMTTQAMSLSLEQQNQRHQ-HQAQT----------------SGATSQPPPSTTAPK
AKKPP--------APQEKPES--NLEPSGV----------GLREDTPE-EAESKPQRPKS
FQQKRDYFQKM---GQE----PIRVKTVKPPAKVQIPQEEMEETE------EEE------
-EE---TAELSP-PPPPPPVVK-KPLKASR------------PKAVKEDEAEPAQEEVPT
QGEDPPVHSSNSAPQHPKPSR-VPPVQSSNSAP-PRPQPSREIRNIIRMYQSRP--GPVA
V-----------PVQPTR--PIKTFQKKNDPKDEALAKL-----------G-----INGV
HLPL-ST--SPNQGKSSPPAVVPRPKARPRLEPSLSIQEKQGPLRDLFGPCSPNPPTAPA
PPPP----PALPPPLSGEPKTPSVESHALTEPMEDKNISTKLLVPSGSVCFSYANAPWKL
FLRKEVFYPRENFSHPYCLSLLCQQILRDTFTESCTRISQDERHKMKGLLGDLEVSLETL
DIVEDSIKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTQSPS
------FHLD--QLKTLCSYSYAEVLTVQCRGRSTLELSLKNEQLILHTAWARAIKAMVD
LFLSE---LRKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDNSLLS-FHRGDLIRLLPVTALEP----------
------------------------GWQFGSAGGRSGLFPDDVVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3152)

PAAAPDLSFSLGKRNS
WQRKSKLG--------P-AQERPTHPRKQ---EPSEDSEATSFTTYSSLSADPHNYTMQE
FALRYFRKPHTW-------LTQMSRDTKEKAAINLIQYTK----DPIQESLTSFCNGDTN
SKAVAGFKALMQFMGDQPKPRGKDELSLLYE

PF00784 // ENSGT00920000148963_7_Domain_5 (3152, 3253)

LLKLCQ--DDLRDEMYCQVIKQVTGHPQP
KHCALGWSVLSLFTGFFAPSTTLMPYVTKFLQDSS-----PSEELARRSQENLQRTVKYG
GRQQLPLPGEMN

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRLLLIHLPGGVDYRTNSQTFTVAGEVLEELCGQMGITDLE
EVQEFALFLIKG----EGELVRPLSPHEYINNVVTD-QDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHSTY
TETHYGQVLRDYLQGKLIVSTQ--AEALLAQLAAFQHFDKTGT-SSPPSEQELLSYIPKP
LQ----WQVNTANIKSLVTQELRQMQGYSKQRAQIGFIE---------------------
------------STAQLPLFGYTVYVVLRVSKLALPGPGLLGLNRQHLVLMDPSS-----
---QELCCSVMLKDLKQLHLLSPLQEDGPPGLELNYGSVDNPQTIWLELPQAQELQHTII
FLLGS---MST---QWPGLL-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MTPSVHPLCLG--SAQT-CLWMAPSWEV
RLSELRQCCFFLLMQDLENRESLTGRMKGGGKIGPTQRGMFPSTGFSGMMQTPVFQPMPS
MMGMPAAPAMMPGAAGIAPMPAMYMP---------QPVVPTVDPSQLAAQQQAFINQQAM
LMAQQMTLQAMNLSQQQQQQQQQ-RQQWRQQPPESSRPRASSPPRSQAPTPAPAPATSPK
PKRSP--------SNRDVTPPPKAPEPPAQ----------PERPIYDS-SSEDDDYPRET
FQQKRAFFQRM---GEQ----KILVKKVRAPSKTWTPPANPQPKEMEEKKKEEEKEKNMT
EEKPSPKTEAAPAAPLPPPEPK------------------------------PKK-----
--------------QTPKARKEPPVV--KPSAPESRPEPSREIRNIIKMYQSRPAPEPQP
I-------------EPSR-RVSKPFIKRNDPKNEALAKL-----------GMMN--LNSP
KSPPPLP---QEKPKGTPPPTKPKP-----GSASSSIKEKQMPLLSIFRQPSSTPPDSPA
PPVLPPLP---SSFPPGNQGLQEFTAKG-LTVTEDDGIKTQLYKLTAGVSFSYFNPPWKI
FLRKEVFYPKENFSHPYCLNLLCEQIIRDTFSDSCLRISREEKHKMKDLLEAFQVGNDAQ
SIQDDGIKKRIVVAARDNWANYFSRLFPVQGENGSDVQILGVSHRGLRL---LKVVKAAA
------YALE--HLKVLCSYSFADVLSVELKDSNSLEFSLKTEQLLLRSHKAPCIKAMVE
LFIQE---LRQDTN

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2984)

YVV-ALRSYVTDDKSLLS-FKKGDLIQLLPMQGLEP----------
------------------------GWQFGSTGGRSGIFPTSLV

ENSGT00920000148963_7_Linker_4_5 (2984, 3147)

QLAAAPDYLSTSMDRRG
GLQKSMKASFEG----------------RNTNREASATSLTSEPYSIMSVPAGDHYTMMD
FASNYFREAQFM-------TELKGTPAEKKTIADMVQHTK----VPIQESLLRYSDSELN
ELAIKSFMTLMRFMGDQPKLKNQDDA

PF00784 // ENSGT00920000148963_7_Domain_5 (3147, 3253)

QCVYEILQLCKEKESLHDEVYCQVIKQVTLNPKQ
ESVLRGWLLLNLLTGFFLPSNILMPYATKFLQQASGDPSSTHHDIAKICQSNLRKNFMYG
GRRHLPFPVEMD

ENSGT00920000148963_7_Linker_5_6 (3253, 3353)

ALLKGRSARRLEILMFGGVEYVTRIRTFTVAKELLQEICEQMGAGEQE
EMQEFALFAIRKASDKNDKIVRPIRMEEYLHDYLLEDMLVTVSLRRLIWKTP

PF00373 // ENSGT00920000148963_7_Domain_6 (3353, 3505)

LHFEDKIY
TDLHYSQIQWDYLKGKILLSYSKELEMQLSVLVMLQHWAKTEQESSVPSREEVKEYIPKP
LQ----SQISTEALQNHLERLLRTMQPLRPVDAKIQFIE---------------------
------------HMMKLPFFGYNIFFVEKVSDSSIPVPCYFGVNKEQIIVVDSIT-----
---QELCHTIPLKELHRMRTLRPTSEQGLPGIELNYGSAASPKTLWIELSQAKEMYHTAV
VILDRTDFQH-----------

MGRNQRKAPQRLERPGRPASGEQESGSASADG-APSRERRSDRGQADKARPAAEPATAGG
QGTPGGRRKPTAEGNGGCRRPGAGLSPKAQERQSNAQRA------AA------GGRLEEG
SLSGGEEL----GGRRRRKRKDKGPSARRGRRTPRSLNGDTSGGDGGSSCPDSETREAQE
SGSQRGRARELRPTPEPTDMGSEGTKTGPESAPEP----S-SDGLVSDWPHADTRGREGS
SGTGPLGASEHSGGNSDSSPLGTGPGRGSRAAM--ASRT--------------------F
EDSSRAPRDTGPAKDASDNRAQ-----RGAEPETMQASTARAPRHQVGKAVGRVPSAAGE
GEAGAAAGA-----GPEDPAPLAALLVVRRLLARXXXXXXXXXXXXXXXXXXX-------
---------------------------XXXXXXXXXXXXXXXXXXGRGSEGRGRGKADEG
RGHERGDEGRGRGKADEGRGHERGYEGRGCGKADEG---------RGHERGDEGRVHQRG
YEGWGRE-PGLRHRLALRLA-GLAGLGGMPRAPPGGRS--PQVPTSPVPGD-PFDQEDKT
PDPKFAVVFPRIHRAGRASSSRSSEEA--SADAPTGEGRGWPRAGAGGHS--EGCRTSGE
GVSGLRRGSLLAPTAPDGPSLDESGSSREAELETLNDEPPVHWAQGSGPHEGPRLGA-AV
LLPRLALETRLQQEGDPGLRGSLRELWEPEDEDEAVLERDLELSLGPGLEAPPFPGAKGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQNTGQDPCILLRGHSGSGKTEAAKKIMQFLSS
LEQDQTGNRECQVEDVLPILSSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIEREQLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLLKALQGLGLCPEELNAVWAVLAAILQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPECLEEAVT----RRVTETPYGQVSRSLPVESAVDARWDALAKALY-SRLFHRL
LRRTNARLAPPGEGGSIGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE-------------------PLRESCLDLLGDQPHSL-LSILDAQTWLSQTE------
------------------------SRCCPGWSA-----VASA---------SRVHAILLP
HHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALEDLIARLGR-SHVYFIQCL
TPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFEAFLA-SFRALGSEGQED
LSDREKCGAVLSQVLGAESPLYHLGATKV--LLQEQGWQRLEELQDQQRSQALVDLHRSF
HTCISRQR----V--LPRMQARM-RGFQARSAGVGARAEVGGPVFTHSSNSCWLTVCLIY
-PWARCWKRYLRWRAALGQLNTILLVAQPLLQ--RRQRLQLG----HWQGWHSSERALER
VPSMELGRLEIPAELAIMLKMAESHRDALAGSITECLPPEVPARPSLTLPADIDLFPFSS
FVAIGFQEPSLPRPGQP-LAKPLTQLDGDNPQRALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQRKLLGALEQSQLASGATRAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------VL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDAWQDLAGCDFVL
DLISQTEDLGD----PACPRSYPITPFGST-------------------PLPGLLLAWEA
PRPGPWL-------Q-PSP-CPTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVISSGLSDLEQSWALSSRMKGGGAIGPTQQ-GYPM-VYPGMIQMPAYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP--------PLPSLDAGQLAIQQQNFIQQQAL
ILAQQMTAQAMSLSLEQQTQQQQ--RQ---------------ARASEAASQASPSAITSK
PRKPP--------TPPEKPQR--DLGSEGG----------CLR-ETSE-EAEDRPYRPKS
FQQKRNYFQRM---GQP----QITVRTMKPPAKVHIPQGEAQEAEEEE---------EE-
QEEQEVETRAVP-SPPPPPIVK-KPLKQGG------------AKAPKEAEAEPAKET-AA
KGHG----------QGPAQGR-GTVVRSSDSKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQP--SRPPKAFLKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SPSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPIAQTPP-
---PPPAP---PLPLPEDPGTLSAERRCLSQPVEDQGVSTQLLAPSGSVCFSYTGTPWKL
FLRKEVFYPRENFSHPYYLRLLCEQILRDTFSESCIRISQNERRKMKDLLGGLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRALAHDPGLEVGAGGK
------VTPV--HARS--LRSFAEVLGVECRGSSTLELSLKSEQLVLHTARARAIEALVE
LFLNE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKVLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKERRSG
WHKGQLSNGEPGLARWDRASERPAHPWSQAHSDDSEATSLSSV-AYGFL-PDSHSYTMRE
FALRYFRRSQAFTLLRATGLGQTDGGATGKDTDSLVQYTK----APIQESLLSLSD-DVS
KLAVASFLALMRFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQQ-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGFFPPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRRMPPPGEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAAEVQEELCRQMGITEPQ
EVQEFALFLIKE----KSQLVRPLQPAEYLNSVVVD-QDVSLHSRRLHWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3459)

HFDNSTY
ISTHYSQVLWDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NPP-SEQDLLAYVPKQ
LQ----RQVNTASIKNLMGQELRRLEGHSPQEAQISFIADLGDQAEQ---V----PGPQQ
SDFLPAPSPPAEAMSQLPLFGYTVYGVLRVSMQALSGPTLLGLNRQHLILMDPSS-----
---QSLYCRIALKSLQRLHLLSPLEEKGPPGLEVNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SCT---EWPSIN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MELGCLEIPAELAVMLKTAEGRQQALAESITESMPPEVPARPHLTLPPDINQFLFSS
FISTNFLDPVLPSPGQP-LAKPLTRLDGENPQHALDINKVMLRLLGDGSLAPWQEQ

PF00784 // ENSGT00920000148963_7_Domain_3 (1797, 1900)

TMGE
YLVRQGQRWPGLRDEIFSQLVAQIWHNPDEQQSQRSWALMAILLSAFPPMPTLQKPLLKF
VSDQAPRGMAALCQHKLLGAMEQTYLAPRMARAHPPTQL

ENSGT00920000148963_7_Linker_3_4 (1900, 2895)

EWTAGWRRGRM--------AL
DIFTFNEECYSAEVESWTTGEQFAGWILQSRGLELPPRGWSVSLHSGDSWQDLAGCDFVL
DLIGQTEDPGD----PISPHSYPIAPHGLA-------------------EDIPPAPGIQA
PSLPPGPPP--APTL-PSR-SYSG---------------------ESRG-SG-NLDGFL-
--DHLFQPVLSPSHSDLEQGWALSSRMKGGGAIGPMQQGSYPM-VYPGMVQMPGYQPAM-
---MPAPMPMMPAMGAVPAMPAMVVPPQPQPQPQPQPLLPSVDQRQLAIQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQRR-HQAQTQAQAQ------AQAQTPGAASPNSPPAVAPK
PKKPM--------APQEEPEH--EPESEI-----------------SQ-EAQENPWQSKS
FRQKQDFFQKM---GQQ----QIKVKTVKPPPKIQIPQAEEQDEEEQDEE----------
------ETRAEP-SPPPPPIVK-KPVTQSK------------AKAAQEAEAKPAARKAEP
-------------------------ADAPKPESRQRAEPSREIRNIIRMYQSRP--GPVP
V-----------PVQPSR-KPSKMFLKKNNPKDEALAKL-----------G-----ISNT
HVPMSMP--SPSPGKGPPPAVAPRPKVPPQLGPSTSIKEKLD----PFGQTPPSAQAP--
-----PPPPAPPLPPPEAPDTLSPGPRGLMEPMEDQGVSTQLLPPSGSVCFSYVSTSWKL
FLRKEVFYPRENFSHPYCLRLLCEQILKDTFAKSCIRITEDERSKMKNLLEDLEVGLDSL
DTTEDNVKKRIVVAARDNWANYFSRIFPVSGESSSDVQLLGVSHRGLRL---LKVTKVPS
------FHLN--QLKTLCSYSYAELLGIECRGSSTLELSLKSEQLVLHTARASTIKAMVE
LFLRE---LRKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVV-ALRSYITDDHSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSTGSRSGLFPADLVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3147)

PAAAPDFSFSPE-RSG
RHQSQLQSREPGLAPWDGAVERHVRPRSQAHSEDS--------IAYASLSTDSHSYTMQE
FALCHFRKPQAL-------LDQTDGLAKDMAMASLVQYTK----APIKESLISLSDEDTN
KQAVESFRVLMQFMGDQPKPRGKNDL

PF00784 // ENSGT00920000148963_7_Domain_5 (3147, 3254)

ELLYELLKLCRE-ENLRDEIYCQVIKQVTCHPQP
EHCTRGWNLLSLLTGCFSPSATLMPYVIKFLQNSG-----SSQELARNSQEHLQRTVKYG
GRQRLPSLGEIQA

ENSGT00920000148963_7_Linker_5_6 (3254, 3353)

FLKGQGMRSLLIHLPGGVDYRTTIQTFTVAAEVVEELCRQMGITDPQ
EMQEFALFLIKK----EGELVRPLLPHEYLNSV-VE-QDTSLHSRRLIWETP

PF00373 // ENSGT00920000148963_7_Domain_6 (3353, 3505)

LHFDNPTY
ITTHYKQVLRDYLQGKLLVNPQ--ADTQLARLAALQHRSQDQE-D-Y-LEQDMLNYLPKP
LR----GHVNIPIIKKLIDQELRQLQVYNSQEAQISFIE---------------------
------------AVSQLPLFGYTVYVVLRVSQMALPGPSLLGLNHQHLIVMDPCS-----
---QKQCCSITLKDLHRLHLLSPLESEGPPGLELNYGSADNPQTIWFELLKAQELMHTIV
FLTDRGL-PS---K-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------DSSAL

PF00063 // ENSGT00920000148963_7_Domain_0 (805, 1529)

LCLKKRFHLGRIYTFGGPLLLSLNPHRPLPLFSAEV
LASYHPKRAPNTTPHILAIAASAYDRLSRSSGQGTCILLGGHSGSGKTEAARKIVQFLSS
LEQEQTRDRRCHLDGVLPVLSSFGHAKTVLNANASRFGQVFCLCVQNGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDPAEREKLSLQGPETYSYLNQ-GQACCLQGKDDAR
DFEGLRKALQV--LCPEEVTAAWAVLAAVLHLGNICFSSSERESQEVAAVSSWAEIHAAA
RLLLVPPECLEGAVT----RRVTETPYGWVCRSLPVESAVDAR-DALAKALY-SRLFTWL
LERSNAQLAAPGEGEHVDTITVVDVYGFEALRV--NGLEQLCNNLASERLQLFSSRLLWA
QEEEACRRELLAWVPVPQ---P-VWDTCLDLLVDQPHSL-LRLLDAQTWLPQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGSHPCYSKPQLPLPIFTVRHCAGTVTYQVHKFVNRNRDHLDPAAVAMLAQSQLQV
PLPALSEPPPLHTVSPHLPES-QSTAGPDKPTLASRFQHSLEDLLARLGR-SHVYFIQCL
TPNPGKLPGLFDVGHVAEQLHQAGILEAVRTRSANFPVRLPFQAFLA-RFRALETEAQGE
SSDRERCGAILSHVLGAESPLCHLGLERV--LLREPGWQQLEQHRAQRRSQALLALHGSL
RTCISRQRLSRLL--LPQMQARV-RGLQA-------------------------------
------RKRYLRRRAALGQLSTVLLVARPLLR--RRQRL---------------------
---QELGRLEIPAEVAVLLKTAEGHHHALDGSITESMPPEVPARTSLSLPPDIDQFPFSS
FISTNFQEPALPSPGQL-LAEPLTRLHGENPQHALDINKVMLRLLGDGTLLPWQEQ

PF00784 // ENSGT00920000148963_7_Domain_3 (1797, 1900)

SMGE
YLVRQGQRRPGLRDEIFSQLVAQIWHNPDEQQTQRSWALMAILLSAFPPMPPLQKPLLKF
VSDQAPTGMAALCQHKLLGALEQAHLAPGMARAHPPTQL

ENSGT00920000148963_7_Linker_3_4 (1900, 2895)

EWTAGRRRGRM--------AL
DIFTFNEECYSAEVESWTTGEQFAGWILQSRGLELPPRGWSVSLHSGDSWQDLVGCDFVL
DLIGQTEDLGD----PVSPHSYPIAPRGLLDTTPIQGTPLAGPTVSHRDEDIAPAPGIQA
PSLP-DPPPGPAPAL-PSR-IQSGK-----ARMGTVRLPVCPI-GESQN-SG-NLDGFL-
--DHLFQPVLSPGHRDLEQAWALSSRLKGGGAVGPMRQGSYPM-A---------------
----------------------MVMPP--QPPPAPQPLLPSVDPRQLAAQQQSFINQQAL
LLAQQMTTQAMTLSLEQQTQWRW-RQAQPQAQ------------APGAASPTSPPPVAPK
PKKPL--------ALQREPER--EV-----------------------------------
------------------------------------------------------------
-------ESSVP-SPPPPRVVT-SAPTQGR------------VKAAQEAEAKPAAQRAGP
GGH-------------------------PAPAPHQRAEPSREIRNIIRMYQSRP--GPVP
M-----------PVQPAR-KPPKNFLKKNNPKDEALGPSPRGMASHLGGPGLSGTQLRTC
FVPPQTP--SPSPGKGPAPAVAPRPKFPPQKPL---------------------------
-----------------------------------RAQRYKLLVPSGSVCFSYLNPSWRL
FLRKEVFYPRENFSHPYCLRLLCEQILKDTFAESCVRISQEERSKMKELLGHLEVGLESL
STTEDSVKKRIVVAARDKWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKMTKGPS
------LHPS--QLKTLCSYSFAELLGVECLGRSTLELTLKSEQLVLHTARASAIKAMIE
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FHRGDLIKLLPVATLEPGIPGGGQGSR
--------HGEGSTWPSRGRAEGPGWQFGSTGGRSGLFPADIVQPAAAPDSSFSPE-RSG
RRKSRLQPREPGLAQWERAAE---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
RACISRQGLG

PF00612 // ENSGT00920000148963_7_Domain_2 (1571, 1631)

RLL--LPRMQARI-RGFQA-------------------------------
------RKRY

ENSGT00920000148963_7_Linker_2_3 (1631, 1793)

LRHRAALGQLNTVLLAARPLLQGRRRQRLQVS----VWVGLLPPAAQLMA
PLCQDLGHLEIPAEVAVMLKTAEGHYQALAGSITESMPPEIPARTSLTLPPDIDQFPFSS
FISTNFQEPALPSPGQP-LAKPLTWLDGENPQHALDINKVMLRLLGDVSLPP

PF00784 // ENSGT00920000148963_7_Domain_3 (1793, 1905)

WQEQSMGE
YLVRQGQRRPGLRDEIFSQLVAQIWHNPDEQKSQRSWALMAILLSAFPPMPTLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQTHLAPGMARAHPPTQLEWTAGWRRGRM--------AL
DVFTFNEECYSAEVESWTTGEQLAGWILHNRGLELPPRGWSVSLHSGDSWQDLLGGDFVL
DLISQTEDLGD----PVSPHSYPIAPHGFA-------------------EDIPPAPGIQA
PSLLPGPPPGPAPEL-PSR-SQSG---------------------DSRT-SG-NLDGFL-
--DHLFQPVLSPGDSDLEQGWALSSRMKGGGSIGPMQQGSYPM-VYPGMMQMPGYQPAM-
---MPAPMPMMPAMGAVPAMPAMVMPPQPQ----PQALLPSVDPRQLAAQQQNFINQQAL
LLAQQMTAQAMTLSLEQQTQQRQ-RQAQPRAQA------------SGAASPTSPPAVAPK
PKKPL--------APREEPER--EPESVGA----------CPQET-SQ-EAREKAPRPMS
FQQKQDYFQKM---GEG----AWGGRPVRKPGHDLGLAG-ARDEDGYEEEEDEN------
-SKQSVRNSSVP-SPPPLLLVP-LPQQLW-------------EEAPREAELRPQESTECS
GGG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

MGRRKGKAPQNPEGSRRPVSGERESGSASADS-APSRERRQGRGKARGERLLLEPGTVGG
QETPGGRRKPTVEEDSDCRRPEAGPPPEAAGRQGSARRKPG---DDR------GGAL-EE
RLPREGRTH--EHDRRRRRGKGRGRSARRSRPETRSLNGDTSGGDGVRSCPDSEAQEAQE
SSSQGGGAPELRPNSEQTDAGSGGTQSGPESG-LE---CPSSDGLSSDPPAKPRNPEGGS
SGARPQGGTEDSGTDTDSSVEGAGPGRSMGRKA--AAS----SFPEG-------------
SHASRASRDPRPAWDVRDSEAGP----TGAEPGKAEALTAQGQHHQVGKVVGKVQGQAGA
SEAGAGV-D-----GPRDSAPLAALVALRRLRGKPPPAPAPQAAGVRSSGLKERFLRAAR
ALGLLRWLRLQLRPQ----EGEAQGAQG--------------------------------
--------------------------------------------------AQGARPRAGE
GRGRG-RAPGLRRRLVLSLA-GVTRRGGRSRAPPGGGSSSQPVVKSPALDD-PN--EEVT
PDPKFAVVFPRIHRAGRASSSQSSEEV--PMDAPAGEGRVRSCAGASGDN--EGRWARGE
GVAGPHPCSVLSPTPPDEPSLNESSSSSEAEPEILEAEAPVHWAQSSDPHEDPGLGTE-A
LLPRLT------LERSPGSCRSLRDRWELEDEAEEALERDLELSLGRDLEASPLPGAEGQ
MGAA-----LNLP-----------------------------------------------
-----------CLGHIC----------------SYPVL

PF00063 // ENSGT00920000148963_7_Domain_0 (879, 1534)

PYGHSGSGKTETARKIVHFLSS
LEQEQTRDRGCQLDDILPMLGSFGHAKTILNANASRFGQVLCLHLQHGVILGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDPREREQLSLQGPETYCFLNQ-GQACRLQGKEDAQ
DFTGLVKALQALGLCAEELTAVWAVLATVLQLGNICFCSSEWESQEVAAVSSWAEIHTAA
RLLRVPPERLEGAVT----RRVVETPYGQVSRSLPLESAIDAR-DALAKALY-SRLFAWL
LRRTNARLAPPGEGGSVVTVTVVDVYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLGLLADQPHSL-LGILDAQTWLSQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGDHPLYAKPQLPLPVFTVRHLAGTVTYQVHKFLNRNRDGLDPAVVEMLAQSRLQL
VGSLFQE-----------AEP-ESRGGRGKPTLASRFQRSLGDLIAQLGR-SHVYAIQCL
SPNPGKLPGLFDVGHVAEQLRQAGILEAVCTRSANFPIRVPFRLFLA-RFRALRTEGQGE
LSDREQCGAILSQVLGAKSDLCHLGATQV--LLREPGWQQLEQHRAEQRTQALLTLHRGL
RVCISCQRLR--L--LPRMQARV-RGLQTRSAGWGEAVSLLQGG--GV----WTP---HY
-PLLASRKSCLRRRAALGQVNAILLVARPLLR--RRQRR---------------------
---QELGRLEIPAELAVMLKTAEGRQHALAQSITESLPPEVPARPNLALPPNIDQFPFSS
FISTGFQVGLGASWLAP-MFPRY-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------VPIQASLLRYSDSELN
ELATKNFQTLMRFMGDQPKHKHQTEV

PF00784 // ENSGT00920000148963_7_Domain_5 (3147, 3254)

RCIYEILQLCKEKENLHDEIYCQVFKQVTHNPQQ
ESEMRGWLLLNLLTGYFLPSKILMPYATKFLQLASSDP-----YIAKICQSNLRKNFLYG
GRRHLPFAVEMEA

ENSGT00920000148963_7_Linker_5_6 (3254, 3354)

LLKGHGARRLVVLMPGGMEYLTRIRTFTVAKELLQEICEQMGIGEQQ
EIEDFVLFAVRS------KMVRPIKLEEYLHDYLLDDKLVSVTLRRLIWRAPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDNQVY
TDVHYGQVLWDYLNGRILLSQSKEMEMQVGLLAMLQHWAKGEQQNSAPSREELKEYTPKS
LQ----ASISPKDLHNHVATLLRTRQPLQPLDAKIQFIE---------------------
------------HVMKLPFFGYTIFVVERISDERVPVPCFFGVNNEEIIVVDGTS-----
---QVVSQAVPLQQLQKMCTLRPISDGGLPGLELHYGSPDSPRALWVELPQAKELYHTIV
VILDKTELHS-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------DSEATSLPSSMACTSLSTDSHNYTMQE
FALCYFRKPLTL-------PTAQ------------PLW---PQ-APIQESLIHLSDENMS
KRAVAGFEALMQFMGDQSKPRGKDEMALLY

PF00784 // ENSGT00920000148963_7_Domain_5 (3151, 3253)

ELLKLCQE-EELRDEMYCQVIKQVTGHPQP
EHCARGWSLLSLFTGFFPPSTTLMPYVTKFLQDSG-----PSQELAQKSQQHLQSTAKYG
GRQRLPLPGEMR

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRQLVIHLPGGVNYRTNLQTFTVAGEVLEEMCGKMGITDPQ
EIQEFALFLIIG----EGELVRPLWPHEYLGTVMLG-QDTSLHSRRLSWESPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPIY
IGTHYGQVLRDYLQGKLMAHPQ--AEAQLAQLAALQHLGRASK-SSP-SEQDLLGYIPKT
LQ----WQVNTATIESLMSQELRRLQGHSSQEAKISFIE---------------------
------------ATRQLPLFGYTVYVVLRVSKLVLPGPALLGLNRQHLVLMDPTS-----
---QTTCCSIALKDLQRVHLLSPLEDNGPPGLELNYGLASNPQTIWLELPQAQELYRTII
FLLD-GNTSST---QWPQ---

MGRNQRKAPQRLERPGRPASGEQESGSASADG-APSRERRSDRGQADKARPAAEPATAGG
QGTPGGRRKPTAEGNGGCRRPGAGLSPKAQERQSNAQRQGRGPRGGR------GGRLEEG
SLSGGEEL----GGRRRRKRKDKGPSARRGRRTPRSLNGDTSGGDGGSSCPDSETREAQE
SGSQRGRARELRPTPEPTDMGSEGTKTGPESAPEP----S-SDGLVSVWPHADTRGREGS
SGTGPLGASEHSGGNSDSSPLGTGPGRGSRAAM--ASRT--------------------F
KDSSRAPRDTGPAKDASDNRAQ-----RGAEPETMQASTARAPRHQVGKAVGRVPSAAGE
GEAGAAAGA-----GPEDPAPLAALLVVRRLLARPPPGAASQAVGPRRAGLKERLLSVAR
ALGLLRWLRRRLRLRRRPPEGEGQRTWPPASEGWGRRKADEGRGHGRGSEGRGRGKADEG
RGHERGDEGRGRG------------------KADEG---------RGHERGDEGRVHQRG
YEGWGRE-PGLRHRLALRLA-GLAGLGGMPRAPPGGRS--PQVPTSPVPGD-PFDQEDKT
PDPKFAVVFPRIHRAGRASSSRSSEEA--SADAPTGEGRGWP----------RGCRTSGE
GVSGLRRGSLLAPTAPDGPSLDESGSSREAELETLNDEPPVHWAQGSGPHEGPRLGA-AV
LLPRLALETRLQQEGDPGLRGSLRELWEPEDEDEAVLERDLELSLGPGLEAPPFPGAKGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQNTGQDPCILLRGHSGSGKTEAAKKIMQFLSS
LEQDQTGNRECQVEDVLPILSSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLLKALQGLSLCPEELNAVWAVLAAILQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPVESAVDARWDALAKALY-SRLFHRL
LRRTNARLAPPGEGGSIGTVTVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE-------------------PLRESCLDLLVDQPHSL-LSILDAQTWLSQTE------
-----------------------FGSCCPGWSA-----MVRSRLTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALEDLIARLGR-SHVYFIQCL
TPNPGKLPGLFDMGHVTEQLHQAAILEAVGTRSANFPVRVPFEAFLA-SFRALGSEGQED
LSDREKCGAVLSQVLGAESPLYHLGATKV--LLQEQGWQRLEELRDQQRSQALVDLHRSF
HTCISRQR----V--LPRMQARM-RGFQARSAGVGARAEVGGPVFTHSSNSCWLTVCLIY
-PWARCWKRYLRWRAALGQLNTILLVAQPLLQ--RRQRLQLG----HWQGWHSSERALER
VPSMELGRLEIPAELAIMLKTAESHRDALAGSITECLPPEVPARPSLTLPADIDLFPFSS
FVAIGFQEPSLPRPGQP-LAKPLTQLDGDNPQRALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLASGATRAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------VL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDAWQDLAGCDFVL
DLISQTEDLGD----PACPRSYPITPFGST-------------------PLPGLLLAWEA
PRPGPW-------LQ-PSP-CPTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVISSGLSDLEQSWALSSRMKGGGAIGPTQQ-GYPM-VYPGMIQMPAYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP--------PLPSLDAGQLAVQQQNFIQQQAL
ILAQQMTAQAMSLSLEQQTQQQQ--RQ---------------ARASEAASQASPSAITSK
PRKPP--------TPPEKPQR--DLGSEGG----------CLR-ETSE-EAEDRPYRPKS
FQQKRNYFQRM---GQP----QITVRTMKPPAKVHIPQGEAQEAEEEE---------EE-
QEEQEVETRAVP-SPPPPPIVK-KPLKQGG------------AKAPKEAEAEPAKET-AA
KGHG----------QGPAQGR-GTVVRSSDSKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQQ--SRPPKAFLKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SPSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLSGQKLPIAQTPP-
---PPPAP---PLPLPEDPGTLSAERRCLSQPVEDQGVSTQLLAPSGSVCFSYTGMPWKL
FLRKEVFYPRENFSHPYYLRLLCEQILRDTFSESCIRISQNERRKMKDLLGGLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRALAHDPGLEVGAGGK
------VTPV--HARS--LRSFAEVLGVECRGSSTLELSLKSEQLVLHTARARAIEALVE
LFLNE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKVLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
WHKGQLSNGEPGLARWDRASERPAHPWSQAHSDDSEATSLSSV-AYAFL-PDSHSYTMQE
FALRYFRRSQAFTLLRATGLGQTDGGATGKDTDSLVQYTK----APIQESLLSLSD-DVS
KLAVASFLALMRFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQQ-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGFFPPSTRLMPYLTKFLQDSG-----PSQELAQSSQEHLQRTVKYG
GRRRMPPLGEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAAEVQEELCRQMGITEPQ
EVQEFALFLIKE----KSQLVRPLQPAEYLNSVVVD-QDVSLHSRRLHWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3459)

HFDNSTY
ISTHYSQVLWDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NPP-SEQDLLAYVPKQ
LQ----RQVNTASIKNLMGQELRRLEGHSPQEAQISFIADLGDQAEQ---V----PGPQQ
SDFLPAPSPPAEAMSQLPLFGYTVYGVLRVSMQALSGPTLLGLNRQHLILMDPSS-----
---QSLYCRIALKSLQRLHLLSPLEEKGPPGLEVNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SCT---EWPSIN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------TFVPDDCASA------------------L----THPHP
HPRRQGQFSRGGDW-----------------PR--PVCLSHSPLTPG------------A
AGE-------------------RPGAAVQQPGQRAPAAL-LLPDAAGPGGGAVSAGVAVL
GARSPASSGVLPGPACRPAPQPPEYPGCPDLAVPXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVHKFLTRNRDRLDLAVAEMLGQSQLQL
VGSLFLE-----------AQP-ELGEGRGRPTLASRFQESLGDLLARLRX-XXXXXXXXX
XXXXXXLPGLFDVGHVAEQLRQAGTLEAVCNRSANFPVRIPFSCFLA-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX--------XX-------XX-XXXX-XXXXXXXXXXXX
XXXX----XX--X--X--XXXXX-X-XX-----------------XXXXXXXXXXXXXXX
XXXXXXXKRYLRRRAALGQLNTILLVARPLLW-RQQ-RRQLG----YSCGRHRSG-GSET
TPSMELGRLEIPAELAAMLKTAEGRQRALEENITESLPPEVPARPSLALPPDIDRFPFSS
YVSTSFQEPSLPRPGQP-LTKPLTRLDGESPQHALDINKVILRLLGVVSLPP

PF00784 // ENSGT00920000148963_7_Domain_3 (1793, 1905)

WQEQVMGE
FLVRQGQRHPGLRDELFSQLVTQLWHNPDEQQTQRGWALMAVLVSTFPPTPTLQKPLLKF
VSDQAPTGMGALCQHKLLGALEQTQLAPGSARAHPPTQLEWKAGWRRGRM--------TL
EVFTFNEESFSAEVESWTTGEQFAGWILESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX----XXXXXXXXXXXXXXV------------------SEDILTAPGFQA
PP----PPPGPAPTL-PHR-DRTR---------------------EAQP-AG-SLDGFL-
--DHLFQPVLSPRFSDLEQSWTLQGHMKGGGSIGPTQQGGYPM-AHPGMMQMPGYQPA--
-M-IPAPVPMMPAMGAVPAMPAMMMPQP------PQPLLPSLDVQQLAAQQQSFINQQAL
LLAQQMTTQAMTLTLEHQTL-Q--RQRQPQ------------AQASRTASPVSPPASAPK
PKKPP--------VPREEPL--------SA----------CSREEA-EEEAEDRAQTIKS
FQQKRDYFQKM---GQQ----QIKMKTARPPAKVQIPQAEEEEEEEEEEATR--------
-------------AEPPTPRTR-KPLKRGT------------AKAAKEXXXXXXXXXXXX
XXXX-----------XXXXXX-XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX--XXXX
X-----------XXXXXX-XXXXXXXXXXXXXXXXXXXX-----------X-----XXXX
XXXXXXX--XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
-----XXXXXXXXXXXXXXXXXXXXXXXLTEPMGDQGVSTQLLAPSGSVCFSYASVPWKL
FLRKEVFYPRENFSHPYCLQLLCRQILLDTFAESCIRISPEERCRMKDLLGDLEVGLDSI
ALTEEGVKKRIVVAARDNWANYFSRIFPVS------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

MGRNQGKAPQRLARPGRPASGEQESGSASADG-APSQERRSDRGQAVRARPAAQPATAGD
QGTAGGRRKPIAEENGGCRRPGAGSPPEAQDRQGSARREGRGPRGGR------RGRLEEG
SLSRGEGR----GGRRRRKGKDPGPSAQRGRRAPRSLDGDTSGGDGGSSRPDSEAREAQE
SGSQRIGARELRPTLEPRVTGSEGTKTGPESA-LE---PSSDSLDSNWPRADPWG-REGS
SGTGPLGASEHSGDDSDSSLLETGPGRGPRAAM--DSRT-----FEG--------S----
---SRAPRDTGPAQDACDNRAQ-----RGTKPETMQASTARAPRHPVRKAAGRVPAAAGE
GEAGAPAGV-----GPEDPAPLAALLVVRRLLARSPPGTTSQAVGPRRAGLKERLLSVAR
ALGLLRWLRRRLRLRPRPPEGEGQGAGPRASEGWGRGK------------------AY--
-------EGRGRGKADDGLGHGRGS------------------EGRGHERGDEGRDHERG
GEGRG-PEPGLRHGLALRLA-GLAGLGGRPRAPPGVLSRPPQVRTSPVPDD-PFDQEDGT
PDPKFAVVFPRIHRAGRASSSRSSEEA--STDAPTGKGRSWPRAGAGGHS--EGRRASEE
GVSGLRRGSLLAPTAPDGPSLDESGSSSEAESETLDDEPPVHWAQGSGPRKGPRLGA-AV
LLPRLALETRLQQEGDPGLRGSLRERWEPEDEDEAVLERDLELSLGPGLEAPPFPGAEGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQHTGQDPCILLRGHSGSGKTEASKKIVQFLSS
LEQDQTRNRGCQVRAR-DYLSSFSQERGGLQASGVSWGQL----KALGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLVKALQGLGLCLEELNAIWAVLAAVLQLGNICFSSSEWESQEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPMEGAIDAR-DALAKALY-SRLFHQL
LRRTNARLAPPGEEGSTGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLDLLVDQPHSL-LSILDAQTWLSQME------
-----------------------FGSCCPGWSA-----MVRSRFTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGYVTEQLHQAAILEAVGTRSANFPVRVPFGAFLA-RFQALGSEGQEG
LSDREKCGTILSQVLGAESPLCHLGATKV--LLQEQGWQRLEELRDQQHSQALVNLHHSF
HTCISRQ--R--V--LPRMQARM-RGFQARSASIGARAEVGVVRPLDS----SFC---PR
-PLPASRKRCLRRRAALGQLNTILLVAQPLLR--RRQRLQLG----HWQGWHSSERALER
VPSMELGRLEIPAELAVMLKTAEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LVKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDTWQDLAGCDFVL
DLISQTEDLGD----PAAPHSYPITPLGST-------------------EAIPLAPGIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVMSSGLSDLEQSWALSSRMKGGGAVGPTQQG-YPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP-----P---LPSLDAGQLAIQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQR---QRQARASEA--------A------SQASPSAITSK
PRKPP--------TPLEKPQH--DLESEGG----------CLRET-SE-EAEDRPCQPKS
FQQKRNYFQKM---GQP----QITVRTVKPPAKVQIPQGEAQEEEEE-----EQ------
-EEQEVETRAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
GGGQG-----------PAQGR-GIVVRSSDPKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKTFLKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SSSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLAPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLDSL
TTTEDGVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRVLAHDPGLEVGAGGK
------VTPA--HARPLR--SFAEVLGVECRGSSTLQLSLKSEQLVLHTARARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHHGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3155)

PAAAPDFSFSKEQRSG
WHKGQLSNGEPGLARWDRASERPAHPWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMQE
FALLF-PRERAL-------PGQTDEGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLGDFRPQAHHSHPS----PHLPFLSPQ

PF00784 // ENSGT00920000148963_7_Domain_5 (3155, 3251)

LCQE-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRWMLPPGE

ENSGT00920000148963_7_Linker_5_6 (3251, 3354)

MKAFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFTLFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3458)

HFDNSIY
ISTHYSQVLRDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NTP-SEQDLLAYVPQQ
LQ----RQVNMASIKNLMGQELRQLGGHSPQEAQISFIGGSG--A------------GTQ
SEFLPAPSPPAEAVSQLPLFGYTVYVALRVSMQALSGPALLGLNRQHLILMDPSS-----
---QNLYCRIALKSLQRLHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------DSEATSLPSSMAYASLSNDSRNYTMQE
FALHYFRKPSTL-------LDQRGGSAQGNVITSLVQYTKVRGQSPIQESLIRLSDEDMS
KQAVAGFQALMQFMGDKSKPRGKEEMDLLYD

PF00784 // ENSGT00920000148963_7_Domain_5 (3152, 3253)

LLKLCSK-EDLRDEMYCQVIKQVTGHPQP
EHCARGWSFLSLLSGFFPPSTTLMPYVTKFLQDSG-----PSQELARTSQEHLQRTVKYG
GRQQLPPMAEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGHAVRLLVVHLPGGVNYRTNGHMFTVAGEVLEELCGQMGIRDPQ
EVEEFALFLIKG----EGELVRPLWPHEYLNRVMVH-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFNHPTY
IKTHYGQVLRDYLQGKLMASAQ--AEHQLAQLAALQHLVRARK-SPP-SGQDLLAYIPKP
LQ----WQVNMATIESLMGQELRQLQGHSPQEAQISFIE---------------------
------------ATSQLPLFGYTVYVVLRVSKLVLPGPALLGLNRSHLILMDPSS-----
---QKLCCSIALKDLQRLRLLSPLEEEGPPGLELNYGLADSPQTIWLELPQAQELQNTII
FLLD-DSISS----TWPGLN-

MGRNQGKAPQRLARPGRPASGEQESGSASADG-APSQERRSDRGQAVRARPAAQPATAGD
QGTAGGRRKPIAEENGGCRRPGAGSPPEAQERQGSARREGRGPRGGR------RGRLEEG
SLSRGEGR----GGRRRRKGKDPGPSAQRGRRAPRSLDGDTSGGDGGSSRPDSEAREAQE
SGSQRIGARELRPTLEPRVTGSEGTKTGPESA-LE---PSSDSLDSNWPRADPWG-REGS
SGTGPLGASEHSGDDSDSSLLETGPGRGPRAAM--ASRT-----FEG--------S----
---SRAPRDTGPAQDACDNRAQ-----RGAKPETMQASTARAPRHPVRKAAGRVPAAAGE
GEAGAPAGV-----GPEDPAPLAALLVVRRLLARSPPGTTSQAVGPRRAGLKERLLSVAR
ALGLLRWLRRRLRLRPRPPEGEGQGAGPRASEGWGRGK------------------AY--
-------EGRGRRKAEDGLGHGRGS------------------EGRGRERGDEGRDRERG
GEGR-----------ALRLA-GLAGLGGRPRAPPGVLSRPSQVRTSPVPED-PFDQEDGT
PDPKFAVVFPRIHRAGRASSSRSSEEA--STDAPTGKGRSWPRAGAGGHS--EGRRASEE
GVSGLRRGSLLVPTAPDGPSLYESGSSSEAESETLDDEPPVHWAQGSGPRKGPRLGA-AV
LLPRLALETRLQQEGDPGLRGSLRERWEPEDEDEAVLERDLELSLGPGLEAPPFPGAEGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQHTGQDPCILLRGHSGSGKTEASKKIVQFLSS
LERDQTRNRGCQVEDVLPILSSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLVKALQGLGLCPEELNAIWAVLAAVLQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPMEGAIDAR-DALAKALY-SRLFHQL
LRQTNARLAPPGEEGSTGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLDLLVDQPHSL-LSILDAQTWLSQTE------
-----------------------FGSCCPGWSA-----MVRSRFTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFGAFLASRFQALGSEGQED
LSDREKCGTILSRVLGAESPLCHLGATKV--LLQEQGWQRLEELRDQQRSQALVNLHHSF
HTCISRQ--R--I--LPRMQARM-RGFQARSASIGARAEVGVVRPLDS----SFC---PR
-PLPASRKRCLRRRAALGQLNTILLVAQPLLR--RRQRLQLG----HWQGWHSSERALER
VPSMELGRLEIPAELAVMLKTAEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LVKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAILLSTFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDTWQDLAGCDFVL
DLISQTEDLGD----PAAPHSYPITPLGST-------------------EAIPLAPGIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVMSSGLSDLEQSWALSSRMKGGGAVGPTQQG-YPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP-----P---LPSLDAGQLAIQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQQ---QRQARASEA--------A------SQASPSAITSK
PRKPP--------TPLEKPQH--DLESEGG----------CLRET-SE-EAEDRPCRPKS
FQQKRNYFQKM---GQP----QITVRTVKPPAKVQIPQGEAQEEEEE-----EQ------
-EEQEVETRAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
GGGQG-----------PAQGR-GIVVRSSDPKP-KQPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKTFLKKIDPKDEALAKL-----------G-----INGA
HSSPPIL--SSSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLAPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLDSL
TTTEDGVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRVLAHNPGLEVGAGGK
------VTPA--HARPLR--SFAEVLGVECRGSSTLQLSLKSEQLVLHTARARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLVS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3155)

PAAAPDFSFSKEQRSG
WHKGQLSSGEPGLARWDRASECPAHPWSQAHSDDSEATSLPSSVSYASLSTDSPNYTMQE
FALLF-PRERAL-------PGQTDEGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLGDFRPQAHHSHPS----PHLPFLSPQ

PF00784 // ENSGT00920000148963_7_Domain_5 (3155, 3251)

LCQE-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRWMLPPGE

ENSGT00920000148963_7_Linker_5_6 (3251, 3354)

MKAFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFTLFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3458)

HFDNSIY
ISTHYSQVLRDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NTP-SEQDLLAYVPQQ
LQ----RQVNMASIKNLMGQELRQLGGHSPQEAQISFIGGSG--A------------GTQ
SEFLPAPSPPAEAVSQLPLFGYTVYVALRVSMQALSGPALLGLNRQHLILMDPSS-----
---QNLYCRIALKSLQRLHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----ACCARIFGLVPGEASALGTTPAV-LGRTGACGRGEG-------------------
NSPGCPPHCH--------------------------------------------------
--------VPPGTAGQRPGAAVQQPRQ----RA--PAAXXXXXXXXXXXXXXXXXXXXXX
XXX--------------------XXXXXXXX-------X-XXXXXXXXXXXXXXX-----
-----------------------XXXXXXXXXX-----XXXXXXXXXXXXX

PF00063 // ENSGT00920000148963_7_Domain_0 (1312, 1513)

ATDHTFLQK
CHYHHGDHPRYTKPQLPLPIFTVRHYAGTVTYQVHKFLNRNQDHLDPAVVEMLAQSQLQL
VGSLFQE-----------AEP-ESGDGPGKPTLTSRFQHSLGDLLAQLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVAEQLRQAGILEAVCTRSANFPVRMPFQAFLA-RFRALGTEGQEE
LSDRERCGTILNQVFGAESPLCHLGATQV--LLQELGWQQLERHRAQQRAQALLTLHRGL
CASLSCQRLR--L--LPRI--RV-RGLQA-------------------------------
------RKWYLRRRAALGQLNTVLLAGRRLLW--RQRRGQLG----HRCSWHGVGA-SKK
GPSMELGHLEIPAELAVMLKTAEGHRHTLAESITEAMPPEVPARPSLTLPPDIDQFPFSS
FISIGFQEPSLPRPGQL-LTKPLTRLDSDNPQHALDINKVMLRFLGDTSLEP

PF00784 // ENSGT00920000148963_7_Domain_3 (1793, 1905)

WQEQTMGQ
YLVRQGQRRPGLRNEIFSQLAAQLWHQPDEQQRQRGWALLAVLLGAFPPVSTLQKPLLKF
VSDQAPGGMAALCQHRLLGALQQTQRAPGSERAHPPTQLEWTAGWRQGRM--------VL
DVFTFTEECFSAEVESWTTGEQLAGRILQSRGLDPPPRGWSVSLHSKDSWQDLAGCDFVL
DLIGQSEDLGD----PAGPHSYPIAPRGLA-------------------EDIPPAPGIQA
PSLPPGPPPGPAPAL-PSR-GHTG---------------------ESRT-SG-SLDGFL-
--DHLFSPC----LSDLEQGRALSGRMKGGGAMGPMQQGSYPV-VYSGMMQMPGYQPAM-
---MPAPVPMMPAMGAVPAMPAVVVPPQ--------PLLPSVDARQLAVQQQNFINQQAL
ILAQQMTTQAMTLSLEQQAKQRQ-SQQ---------------AQAPGAASLTPPPAVSPK
PKKTP--------TPQKEPER--DLELVGA----------CLRET-SE-EAEHRPRRPKS
FQQKRDYFQKL---GQQ----QIKVEMMRPPAKVKIPQGEEQEEEPEEEE----------
-------PRAVP-SPPPPPVVK-KPLARDG------------AKAAQEAEAEPATEAGPG
GGRRP-------------AEG-RAVVRSSDPKP-RRAEPSREIRNIIRIYQSRP--GPVP
V-----------PVQPPR--PPQIFLKKNNPKDEALAKL-----------G-----ISGA
SSLPSTL--SPSPGKGPPPAVAPRPEGQPRRVPSNSIKEKQGPLQELFGQNPPTAQSP--
-----PPPPAPPLPPPLDPATPPAEPHSFVETMGDQGISTQLLVPSGSVCFSYASAPWRL
FLRKEVFYPRENFSHPYCLRLLCEQILRDTFAESCIRISQDERHRMKDLLRDLEVGLDSL
DTAEDSVKKRIVVAARDNWANYFSRIFPVSGEGGTDVQLLAVH-RGLKLLXXXXXXXXXX
------XXXX--XXXXXX---XXXXXXXXXX---XXXXXXXX--XXXXXX---XXXXXXX
XXXXX---X-XXXXXXX-XXXXXXXXXXXXXX-XX---X--------------XXXXXXX
--------XXXXXXXXXXXXXXXPGWQFCSTGGRSVLFPADIVQPAAAPDFSFSMEQRNG
QHKSQLRHG-----EWDKASEVRKAGDAEARPN---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MLFILPAALMQFMGDQSKPRGKDELDLL

PF00784 // ENSGT00920000148963_7_Domain_5 (3150, 3253)

YKLLKLCQE-KDLRDEMYCQVIKQITGHPKP
EHCARGWSLLSLFTGFFPPSTTLMPYVTKFLQDSG-----PSQELAQRSQQHLQRTVKYG
GRQRLPQPGEIR

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRLIVIHLPGGVDYRTNVQTFTVAGEVLEEMCGQMGITDPQ
EVQEFALFLIKG----EGELVRPLWPHEYLNAVVVN-QNISVHSRRLSWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPVY
TGTHYAQVLRDYLQGKLMGRAP--ADTQLAQLAALQHLGRASK-SPP-SEQDMLDYIPKT
LQ----WQVNMDIIKSLTGQELRQLQGHSPQDAQISFIE---------------------
------------AMRQLPLFGYTVYVVLRVSKLVLPGPALLGLNRQHLVLMDPTS-----
---QKMCCSIALKDLQRLHLLSPLEPNGAPGLELNYGSADSPQTIWLELPQAQELHHTII
FLLD-GSASSAQWFQWPSLS-

MGRNQGKACQRLARPGRPASREQESGSASADS-APSRERRYDRGQADKARPAAERATAGG
QGTAGGRKKPTAEENGGCRRPGAGSPPRAQERQGSARRQGRGPRDGR------GGRLEEG
SLSGE------------------------------DLYGDTSGGDGGSSCPDIEAREAPE
SGSQRGGARELRPTPEPTNTGSEGTKTGPESALDT----S-SDGLDSDGPQAHPRSRVGS
SGAGPLGASEHSRGDSDSSLLGAGPGLGPRGAT--ASKT--------------------F
EGSSRSPRDTGPAQDASDNRAQ-----RGAEPETGEGSTARAPRRQVRKALGPVPPAAGE
GEAGAAAGA-----GPEEPAPLASLLAVRRLLARPPPGAASQVVGPRRPGVKERLLRVAR
TLGFLNWLRLR--LKLRPPEGEGLGAAPRASERRGRGKAGEGRSHGRGGEGRSRGKADKG
RGHESGDEGRGCGKENDGRVQRKADEGRGYGRAD-----E----GRGHERGDKGRGRGRA
DEGRG-HEPGLRRRLALRLA-GLAGLEGSPAAPRGGRSRPLQVPTSPVPDD-AFDQEDGT
PDPKFAVVFPRIHRAWGASSSHSSGEASASADVPTGEGRGWPGAGAGGHS--EGRRASGE
GVSWPHLGSLLALTAPDGPSLDESGSSSETESETLDDEPPVHWARGSGPREGPGLGT-AV
LLPRLALETRRQREGDLGPRRCLRERWEPEDEAEAVLEWDLELSLGPGLETPPFPGAEGS
SLADSLEDAEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1534)

HIFAIVASAYD-LAQNTGQDPCILLRGHSGSGKTEAAKKIVQFLSS
LKQDQTGNRGCQVEDVLPMLSSFGHAKTTLNANASRFGQVFCLYLQQGVIVGACVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSVERERLSLQGPETYYYVNQ-GQACRLQGKEDAQ
DFEGLVKALQGLGLCPEELNAVWAVLAAILQLGNICFSSSEHESQEVAAVSSWAEIHTAA
RLLRVPPERLEAAIT----RRVTETPYGQVSRSLPVESAVDAR-DALAKALY-SRLFHRL
LKRTNMWLAPPGEGSSIGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE-------------------PPRESCLDLLVDQPHSL-LSILDAQTWLSQVE------
-----------------------FGSRCPGSSA-----MLQSQLTTTSASQATDHTFLQK
SHYHHGDHPSYTKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAAVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGERGRPTLASRFQQALGGLIAQLGR-SHVYFIQCL
SPNPGKHPGLFDVGHVAEQLHQEAILEAVGTRSANFPVRLPFEAFLA-RFWALVSEGQED
LSEREKCGTILSQVLGAESPLCHLGATKV--LLREQGWQQLEELRAQQRSQALLSLHRGL
HTCISSQR----L--LLRMQAHV-RGLQSRSAGVGARAEVGGPVFTHPSNSFRLTIRLLC
-PGKRC----LRRRAALRQLNTILLVAQPLLR--RRQRLQLG----HWRGWHSSRRASER
VPSMVGGL-----------EDGGCHQDTLAGSITESLPPEVPARPNLSLPPDIDRFPFSS
FVSVGFREPSLPMPGQP-LSKPLTQLDGENPQHALDINRVMLRLLGDGSLESWERQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQRRPGLRNELFSQLVAQLWQNRDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGAARAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDEWQDLAGCDFVL
DLISQTEDLED----PAGPHSYPITPLGPA-------------------EAIPPAPGIRA
PSLPPAPPPGPAPTL-PSR-GHTG--------------------------SG-SLDGFL-
--DDIFQPVISSSHSDLEQSRTLSSRMKGGGAIGPTQQ-GYPV-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGAVPAMPPMVVPPQP-----AQPLLPSLDVGQLAIQQQNFINQQAL
ILAQQMTAQAMNLSLEQQTRQRQ--QR---------------AQASEAASQALPSPITSK
PKKPP--------TPPEESQH--ALETEGGS----------RR-ETSE-EAEDKPCQPKS
FQQKRNYFQKM---GQP----QITVRTMKPPAKIQMPQEEEPEEEEEEEEEEQ-------
EEQEEDRIEAPS-TLPPPCIAK-KPLKQGG------------AKAAKEAEAEPAKEA-AT
KVRS----------QGPAQGR-GTVVHSSDPKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQP--SRPPKAFLKKSDPKDEALAKL-----------G-----ISGT
HLSPLSVCCFPGRRKGPPPAVAPRPKIPLRPGPSSSIKEKQGPLLDLFGQNLPTSQTPS-
---PPPAPPAPPLLPTKDPEALSVGHHRSTQPMEDQGLSTQLLEPSGSVCFSYTGTPWKL
FLRKEVFYPRENFSHPYCLRLLCEQILRDTFSESCIRISRDERHKMKDLLGDLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSVSGPSGCWLMSLRRQVWGAGWEAGWGQGLG
------VWAK--SL---------EVWGARGRGEASRGNR-----WAGRTG--RHRQACCS
QPSPA---CLQDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2984)

YVI-ALRSYITDNSSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIA

ENSGT00920000148963_7_Linker_4_5 (2984, 3148)

QPAAAPDFSFSKEQRSG
RHKGQLSNGELGLTRWDRPSERPAGPRSQVHSDDSEATSLPSSAAYASLPTDSSNYTMQE
FALRYFRKSEDNPCA------C-LP-------TASSLWLQ----APIQESLLILSD-DMS
KQAVVSFLALMQFMGDQSKPRGKDDMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQE-EQLRDEIYCQVIKQVTGHPRP
GRCIRGWSFLSLLTGFFSPSTKLMPYLTKFLQDSG-----LNQELARSSQEHLQSTVKYG
GRQRLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAADVQEELCRQMGIMEPQ
EVQEFALFLIKG----EGELVRPLRPAEYLNNVVVD-PSVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3459)

HFDNPTY
ITTHYNQVLRDYLQGKLLVSAQ--ADAQLARLAALQHLSKANR-NTP-SEQDLLAYVPKQ
LH----RQVNTASIKNLMEEELRRLEGHRPQEAQISFIADLGGQALR---V----PGPQQ
SEFLPASSPTPEAVRQLPLFGHTVYVVLRVSTQALPGSALLGLNRQHLILMDPSS-----
---QSLCCRIALKSLQRVHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLMDSNA-SCT---EWPSIN-

MDRNQGKTSQRLARPGRPASREQESGPASTDS-APNRERRHDRGQADKARPAAERATAGG
QGTAGGRKKPTV-ENGGCRRPGASSPTEAQERQGSARCQGRGPRDGR------GGRLEEG
SLSRE-ER----GGRRRRKGKGRESSALRDHRAPRSLYGDTSGGDGGSSCPDSEAREAPE
SGSQRGGARELRPTPEPTNTGSEGTKTGPESALDL----S-SDGLDSDGPRAHPRSREGS
SGAGPLGAS---------DLLGAGPGQGPGGAT--ASRT--------------------F
EGSSRSPRDTGPAQDPSDNRVQ-----RGAKPETGEGSTARAPRRQVGKALGPVPPAAGK
GEAGAAAGA-----GSEEPAPLASLLAVRRLLARPPPGAASQVVGPLRPGLKERLGRVAR
TLGLLSWLRLR--LKLRPPEGEGLGADPRASEGRGRGKADKGRIHESGDEGRGCGKADDG
RGSRKADEGRGYGRGD---------EGRGYGRADEGRGHE----GRGHETGDKGRGRGRA
DEERG-HEPGLRRRLALRLA-GLAGFGVSPTAPPGGRSCPLQVPTSPVPDY-PFDQEDGT
PDPKFAVVFPRIHRAGRASSSHSSGEASASADVPTGEGRGWPGAGEWGHS--EGRRASGE
GVSWPHPGSLLSSTVPDGPSLDESGSSSETESETLDDEPPVHWAQGSGPREGPGLGA-AV
LLPRLALETRQQPEGDLGPRGSLRERWEPEDEAEAVLERDLELSPGPGLEMPPFPGAEGR
SLADGLEDAEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1170)

HIFAIVASAYD-LAQNTGQDPCILLRGHSGSGKTEAAKKIMQFLSS
LEQDQTGNRGCQVEDVLPILSSFGHARTTLNANASRFGQVFCLYLQQGVVVGARVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSVERERLSLQGPETYYYLNQ-GQACTLQGKEDAQ
DFEGLVKALQGLGLCPEELNAVWAVLAAILQLGNICFSSSEHESQEVAAVSSWAEIHTAA
RLLRVPPERLEAAIT----RRVTETPYGQVSRSLPVEGAVDARWDALAKALY-SRLFHRL
LKRTNVWLAPPGEGGSIGTVTIVDAYGFEVTPW--GGVQDRGRSYNSLQLSL---GELKR
YLP-------------------PPRESCLDLLVDQPHSL-LSILDAQTWLSQVE------
-----------------------FGSHCP------------------------DHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAAVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGERGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
SPNPGKHPGLFDVGHVAEQLHQAAILEAVGTRSANFPVRLPFEAFLA-RFRALGSEGQED
LSEREKCGTILSQVLGAKSPLCHLGATKV--LLREQGWQQLEELRAQQHSQALLSLHRGL
HTCISSQR----L--LLRMQARV-RGFQSRSASVGARAEAGGPVFTHSSNSCWLTICLLC
-PGKRC----LRRRAALGQLNTILLVAQPLLR--RRQRLQLG----HWRGWHSSRRASER
VPSMELGRLEIPAELAVMLRMAEGHQDALAGSITESLPPEVPARPNLSLPPDIDRFPFSS
FVSIGFQEPSLPMPGQP-LSKPLTQLDGENPQHALDINRVVLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQRRPGLRNELFSQLVAQLWQNRDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQLQLAPGATRAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDEWQDLAGCDFVL
DLISQTEDLGD----PAGPRSYPITPLGSA-------------------EAIPPAPGIRA
PSLPPGPPPGPAPTL-PSR-GHTG---------------------EAQK-SG-SLDGFL-
--EDVFQPVISPGRSDLEQSRTLSSRMKGGGAIGPTQQ-GYPM-VYPGMIQVPGYQPGM-
---VPAPMPMMPAIGAVPTMPPMVVPPQP-----AQPLLPSLDAGQLAVQQQNFINQQAL
ILAQQMTAQAMNLSLEQQTRQRQ--RR---------------AQASEAASQAPPSAITSK
PKKPP--------TPTEESQH--LGLQGRGHGQGEQGCGECGT-WSGW-EAEDRLCQPKS
FQQKRNYFQKMVGVAHP----GITVRTTKPPAKIQIPQGEEQEEEEE-------------
-EEEQDRSAAPS-TLPPPYIMK-KPLKQGG------------AKAAKEAEAEPAEEA-AA
KGRS----------QGLAQGR-GTVVHSSDPKP-KRPQPSREIGNIIRMYQSRP--GPVP
M-----------PVQP--SRPPKAFLKKSDPKDEALAKL-----------G-----INGA
HSPPLML--SPGPGKGPPPAVAPRPKAPPQPGPSSSIKEKQGPLLDLFGQNLPTAQTSP-
---PPPVPPAPPLLPPKDPETLSLGHHRSTQPMEDQGLSTQLLEPSGSVCFSYTGTPWKL
FLRKEVFYPRESFSHPYCLRLLCEQILRDTFAESCIRISRDERHKMKDLLGDLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGENGSDVQLLAVSHRG------LRLLKVTQ
------VWAK--SL---------EVWGARGRGEASGGNR-----WAGRTG--RRRQAHCS
RPSPA---CLQDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNSSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3152)

PAAAPDFSFSKEQRSG
RHKGQLSNGELGLTRWDRASESPAGPQSQTHSDDSEATSLPSSAAYASLPTDSSNYTMQE
FALRYFRKNQAVLLA------LSLPGAARKDTDSLVQYTK----APIQESLLILSD-DMS
KQAVASFLALMQFMGDQSKPRGKDGMDLLYG

PF00784 // ENSGT00920000148963_7_Domain_5 (3152, 3253)

LLKLCQE-EQLRDEIYCQVIKQVTGHPRP
ERCIRGWSFLSLLTGFFSPSTKLMPYLTKFLQDSG-----LSQELAQSSQEHLQRTVKYG
GRRRLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3355)

AFL--------------------------VAADVQEELCRQMGIVEPQ
EVQEFALFLIKG----EGELVRPLRPAEYLNNVVME-QNVSLHSRRLGWEIPLH

PF00373 // ENSGT00920000148963_7_Domain_6 (3355, 3459)

FDNSTY
ITTHYSQVLRDYLQGKLPVSAQ--ADAQLARLAALQHLSKTNS-NIP-SEQDLLDYVPKQ
LH----RQVNTASIKNLMEQELRRLEGHRAQEAQISFIADLGGQALR---V----PGPQQ
SEFLPASSPPTEAVRQLPLFGHTVYMVLRVSMQALPGSALLGLNRQHLILMDPSS-----
---QSLCCCIALKSLQRVHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTI
FLMDSNA-SCT---EWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MQE
FALRFFRKPQTL-------LDPTGKDANSKDTVSLVQYTK----VPIQESLISFHDEDNN
KQAVESFRILMQFMGDQSKPRA

PF00784 // ENSGT00920000148963_7_Domain_5 (3143, 3255)

KNKEELLHELLKLCQR-ENLRDEIYCQVIKQITEHPQP
ERCAQGWKFLSLLTGFFPPSTTLMPYVTKFLQDAD-----MSQELARGSREHLQHTVKYG
GRRQLPLPGEMKAIMKGREVRWLLVHLLGGVGYRTNIQTFTVVAEVLEELCQHMGVTDPQ
EVQEFALFLIKG----EGGLARPLWPSEYLNNVLVT-DDVQLHCRRLGWERPLRFHNPTY
VSVHYSQVLRDYLQGKLLVKAQ--ADAQLAHLAALQHLSKDAQ-DLP-SEQDLLLYVPKQ
LQ----WQVNQAAIKGLMDQELRRLQGHSPKEAKISFIE---------------------
------------ATRQLPLFGYTVYVVLRVSQPALSETGLLGLNRHNLVLMDSIS-----
---QRLCRSITLSHVRRLQLLSPRKEGGPPGLEIHYCSVQNPQSIWLELPQAQELKYTIS
FLLNCST-TQ---ATR-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MDAS
SIPEDGIKKRIVVAARDNWTNYFSRLFPVKGDSGSDVQILGVSHRGLQL---LKRAKEVS
------FSPE--YLKLLCSYSYADVLSLELMGQNILQFSLKNEQLVLHSPKACQIKAMVE
LFLNE---LKQDSK

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2984)

YVI-ALRSYTTDNKSLLN-FKKGDLIRIVPMEGLEP----------
------------------------GWQFGSVGGRSGLFPSSMV

ENSGT00920000148963_7_Linker_4_5 (2984, 3145)

QLAAPPDYLSLHVNREE
EGRKSLRRGTQE----------------KIITKENSTTYVPLEVGSTSTAPETCHYTMME
FAAAHFRGAQPK-------LGWQEMSAELEDPALLVQHTK----VPIQESLLFYSNSKMN
DLATKAFMTLMRFMGDAPGIKKQK

PF00784 // ENSGT00920000148963_7_Domain_5 (3145, 3254)

EVDYINEILQLCKEKENLRDEIYCQVIKQVTQNPEH
DRSHRGWQLLSLLTGYFLPSSILLPYVTKYFQQASFDSSSPFIEIARICQSNLRKMVLNG
GRRRLPFHGEMEA

ENSGT00920000148963_7_Linker_5_6 (3254, 3355)

FLKGRSSRRIVIRLPGGQGYPTKLKTFTIAADIMKEISEHLGIADQE
EIQEFAIFASRG----HGKVLRPLRQKEYLHDYLLEDSFVELSFSRITWKIPLH

PF00373 // ENSGT00920000148963_7_Domain_6 (3355, 3505)

FENENY
INFHYNQVLQSYTTGKLLLQCSGELEQQVVTLALLQHWAKGTG-SLPSTREELRSCIPDP
MV----HLINLEIIHDFVTHHLEQRQPLEQHEAKIQFIE---------------------
------------HMVQIPLFGYNVYFVERISIPGLVKPCFIGVNQEQIIIVDGKL-----
---QNLYCRIPLKEIQRMRTMPPLDESGTPGLEVNYGSPDDPKTIWFELKQAKLLYHTIA
IIAEEATDSQV----------

MGRNQGKAHQRLARPGRPASGEQESGSASADG-APSQERRSDRGQAVRARPAAQPATAGG
QGTAGGRRKPIAEENGGCRRPGAGSPPEAQERQGSARREGRGPRGGR------RGRLEEG
SLSRGEGR----GGRRRRKGKDPGPSAQRGRRAPRSLDGDTSGGDGGSSCPDSEAREAQE
SGSQRSGAQELRPTLEPRVTGSEGTKTGPESA-LE---PSSDSLDSNWPRADPWG-LEGS
SGTGPLGASEHSGGDSDSSLLETGPGRGPRAAM--ASRT-----FEG--------S----
---SRAPRDTGPAQDASDNRAQ-----QGAKPETMQASTARAPRHRVRKAAGRVPAAAGE
GEAGAPAGA-----GPEDPAPLAALLVVRRLLARSPPGTTSQAVGPRRAGLKERLLSVAR
ALGLLRWLRRRLLLRPRPPEGEGQGAGPRASEGWGRGK------------------ADDG
LGHGRGSEGRGRGKADDGLGHGRGSEGWGPKRGDEGRGRGRGDEGRGCERGDEGRDHERG
GEGRG-PEPGLRHRLALRLA-GLAGLGGRPRAPPGVLSRPPQVRTSPVPDD-PFDQEDGT
PDPKFAVVFPRIHRAGRASSSRSSEEA--STDAPTGKGRSWPRAGAGGHS--EGRRASEE
GVSVLRRGSLLAPTAPDGPSLDESGSSSEAESETLDDEPPVHWAQGSGPRKGPRLGA-AV
LLPRLALETRLQQEGDPGLCGSLRERWEPEDEDEAVLERDLELSLGPGLEAPSFPGAEGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQHTGQDPCILLRGHSGSGKTEASKKIVQFLSS
LEQDQTRNRGCQVEDVLPILSSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLVKALQGLGLCPEELNAVWAVLAAVLQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPMEGAIDAR-DALAKALY-SRLFHQL
LRRTNARLAPPGEEGSTGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLDLLVDQPHSL-LSILDAQTWLSQTE------
-----------------------FGSSCPGWSA-----MVRSRFTTTSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLSSRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFGAFLASRFQALGSEGQED
LSDREKCGTILSQVLGAESPLCHLGATKV--LLQEQGWQRLEELRDQQRSQALVNLHRSF
HTCISRQ--R--V--LPRMQARM-RGFQARSANIGARAEVGVVRPLDS----SFC---PR
-PLPASRKRCLRRRAALGQLNTILLVAQPLLR--RRQRLQLG----HWQGWHSSERALER
VPSMV--------------GGLEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LVKPLTQLDGENPQHALDINKVMLRLLGDGSVESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDTWQDLAGCDFVL
DLISQTEDLGD----PAAPHSYPITPLGST-------------------EAIPLAPGIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVMSSGLSDLEQSWALSSRMKGGGAVGPTQQG-YPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP-----P---LPSLDAGQLAIQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQR---QRQARASEA--------A------SQASPSAITSK
PRKPP--------TPLEKPQH--DLESEGG----------CLRET-SE-EAEDRPCRPKS
FQQKRNYFQKM---GQP----QITVRTMKPPAKVQIPQEEAQEEEEE-----EQ------
-EEQEVETRAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
GGGQG-----------PAQGR-GIVVRSSDPKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKTFLKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SSSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLAPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLDSL
TTTEDGVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRVLAHDPGLEVGAGGK
------VTPA--HARPLR--SFAEVLGVECRGSSTLQLSLKSEQLVLHTAWARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3155)

PAAAPDFSFSKEQRSG
WHKGQLSNGELGLARWDRASERPAHPWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMQE
FALLL-PRERAL-------PGQTDGGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLGDFRPQAHHSHPS----PHLPFLSPQ

PF00784 // ENSGT00920000148963_7_Domain_5 (3155, 3251)

LCQE-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRWMLPPGE

ENSGT00920000148963_7_Linker_5_6 (3251, 3354)

MKAFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFTLFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3458)

HFDNSIY
ISTHYSQVLRDYLQGKLPVSAK--ADAQLARLAALQHLSKANG-NTP-SEQDLLAYVPQQ
LQ----RQVNMASIKNLMGQELRQLGGHSPQEAQISFIGGSG--A------------GTQ
SEFLPAPSPPAEAVSQLPLFGYTVYVALRVSMQALSGPALLGLNRQHLILMDPSS-----
---QNLYCRIALKSLQRLHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MQE
FALQHFRKPQTL-------LDQTEGGATEKAMASLVQYTK----APIQESLISLSDEDMN
RQAVESFRTLMQFMGDQAKPRD

PF00784 // ENSGT00920000148963_7_Domain_5 (3143, 3255)

KDEMALLYELLKLCRE-ENLRDEIYCQVMKQVTGHPQP
ELCARGWKLLSLLTGFFTPSITLMPYLTKFLQDSG-----QSQELARSSQEHLQRSVKYG
GRRRLPYPGEMKAFLKGKMAYLLLIHLPGGVHYKTKIHTFTVAAEVLEELCEKMGIMDPE
EVQEFALFLVKG----EGKPVRPLRPHEYINSV-VD-EDTSLHSRRLSWETRLHFDNLAY
INTHYSQVQRDYLEGKLLVSAQ--ADAQVARLAALQLLSGAHE-DPP-SEQDLLAYLPNP
LQ----WQGSMATIKSLTGQELRQLQGCSSQEAQISFIE---------------------
------------AVSQLPLFGYTVYVVLRVSQLALPGPSFLGLNRQHLILMDPGS-----
---QTLFCTIALSDLHRLHL-SPREAGGPPGLELSYGSADSPRTIWLELPQAQELRHTIT
FLLDSSN--A---PAWSHAR-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------PA----CCA---

PF00063 // ENSGT00920000148963_7_Domain_0 (1099, 1534)

-RAFALDPVGCA--------------------SA-LGIAPPV
LERIQA-APEADEGHCPT-------------------CPPHCHMPAG------------T
EGE-------------------WPGATVQQPCQA-PAAP-LHPD-AARPGGGVSARVAAL
GAYPPVSKGFLPGPSGRPAPQPPEYFGCPDVAV-----------------PATDHTFLQK
CHYHHGDHPSYTKPQLPLAIFTVQHYAGTVTYQVHKFLNRNRDHLDPAVVEMLAQSQLQL
VGSLFRE-----------AEP-EAGGGRDKPTLASRFQKSLGDLLARLGR-SHVYFIHCL
NPNPGKLPGLFDVGHVAEQLRQAGILEAVCTRSANFPVRVPFQAFLA-RFRTLGTEGQGE
LSDRERCGAILSQVLGAESPLYHLGATQI--LL

ENSGT00920000148963_7_Linker_0_2 (1534, 1569)

QEPGWQQLEQHRAQHRSQALLTLHRGL
LTCISRQR

PF00612 // ENSGT00920000148963_7_Domain_2 (1569, 1631)

LR--L--LPRIQARV-RGLQA-------------------------------
------RKRY

ENSGT00920000148963_7_Linker_2_3 (1631, 1793)

LQRRAALGQLNTILLVTRPLLW-RRR-KLRLG----HWRGWHGGG-ASKN
TSSMELGRLEIPAELAVMLTAER--QHTLVQKITEALPPEVPAQTSLTLPPDIDQFPFSS
FISTGFQEPSLPSPGQL-LAKPLTRLDGENPQLALHVNKVMLRLLGDGSL-L

PF00784 // ENSGT00920000148963_7_Domain_3 (1793, 1905)

WQEQTMGT
YLAKQGQRQPGLRDELFSQLVAQLWRNPDEQQSQRGWALMAVLLSAFPPLPTLQKPLLKF
VSDQAPTGMAALCQHKLLGALEQTQLAPGVIRAQPPTQLEWTAG

ENSGT00920000148963_7_Linker_3_4 (1905, 2895)

WRRGRM--------AL
DVFTFNEERFSAEVESWTTGEQFAGWILWSRGLEGPPRGWSVSLHSRDSWQDLAGCDFVL
DLIGQTEDLGD----PAGPHSYPIAPQSL-------------------AEDIPPAPGVQA
PSLPPGPPPGPAPPL-PSR-SHTG---------------------ESRT-SG-NLDGFL-
--DHLFKPVLSG------LSWFLKSRMKGEGAIGPMQQSSYPM-MYPGMMQVPGYQPA--
-M-MPPPMPMMPAMGAIPAMPAMMVPPQPQ----LQPLIPSVDPSLLATQQQNFINQQAL
ILAQQMTAQAMSLSLE-QQTQQRRH----Q------------AQAPGAASHTPAPAIFPK
PKKAP--------APQEEPER--DLESVGA----------PLEETS---QGEHRPQRPKN
FQQKRDYFQRL---GQQ----QSKVKMVKPPTKVQIPQGEEQEEEQEEEEPHT---G---
--------AAPAPSPPPSPVVK-KPLTLDG------------AKAAREAEAQPAQEVGSG
-DGP-----------RLA---------RLGLKA-KCRTPSREIGNIIRMYQSRP--GPVP
E-----------PVQPF--RPPKTFLKKNNPKDEALAKL-----------G-----ITGG
HLSSSTP--SPSPGKGPPPAVAPRPKAPLRFETSSSIKEKQGPLQELFGQTPPATQAP--
-----PPPPAPPPPLAGDPGTPSAELCGRMEPMGDQGICTQLLVPSASVCFSYTSAPWRL
FLRKEVFYPRENFSHPYSL-LLCEQILRDTFAESCIRISQDERHKMKDLLGDLEVGLDSL
VTTEDSVKKRIVMAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTRSPS
------FHPN--QLKILCSYSFAEVLGLECRGSSTLELSLKNEQLVLHTARASAIKAMVE
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2986)

YVV-ALRSYITDDGSLLS-FHRGDLIKLVPMASLEP----------
------------------------GWQFGSTGGRSGLFPANMVQPAAAPDFSFSPEPRTG
QHKSRPQRREPGLAQCDSTLEVRKTGEVEASPD---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

MGRHQGKAPQRLARPGRPASGEQESGSASADG-APSQERRSDRGQAVRARPAAQPATAGG
QGTAGGRRKPIAEENGGCRRPGAGSPPEAQERQGSARREGRGPRGGR------RGRLEEG
SLSRGEGR----GGRRRRKGKDPGPSAQRGRRAPRSLDGDTSGGDGGSSCPDSEAREAQE
SGSQRSGARELRPTLEPRVTGSEGTKTGPESA-LE---PRSDSLDSNWPRADPWG-LEGS
SGTGPFGASEHSGGDSDSSLLETGPGRGPRAAM--ASRT-----FEG--------S----
---SRAPRDTGPAQDASDNRAQ-----RGAKPETMQASTARAPRHLVRKAAGRVPAAAGE
GEVGAHAGA-----GPEDPAPLAALLVVRRLLARSPPGTTSQAVGPRRAGLKERLLSVAR
ALGLLRWLRRRLRLRPRPPEGEGRGAGPRASEGWGRGKACEGRG---------RGKADDG
LGHGRGSEGRGRGKADDGLGHGRGSEGRGPKRGDEGRGRGRG---------DEGRDHERG
GEGRG-PEPVLRHRLALRLA-GLAGLGGRPRAPPGVLSRPPQVRTSPVPDD-PFDQEDGT
PDPKFAVVFPRIHRAGRASSSRSSEEA--STDAPTGKGRSWPRAGAGGHS--EGHRASEE
GVSGLRRGSLLAPTAPDGPSLDESGSSSEAESETLDDEPPVHWAQGSGPRKGPRLGA-AV
LLPRLALETRLQQEGDPGLRGSLRERWEPEDEDEAVLERDLELSLGPGLEAPPFSGAEGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_1 (855, 913)

HIFAIVASAYD-LAQHTGQDPCILLRGHSGSGKTEASKKIVQFLSS
LEQDQTRNRGYQ

ENSGT00920000148963_7_Linker_1_0 (913, 947)

VRARLETLVGLLVHEAPGWFASWALTPIFC--AP

PF00063 // ENSGT00920000148963_7_Domain_0 (947, 1533)

RGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLVKALQGLGLCPEELNAVWAVLAAVLQLGNICFSSSERESQEVAAVSSRAEIHTAA
RLLRVPPECLEGAVT----RRVTVSP--RVSRSLPMEGAIDAR-DALAKALY-SRLFHQL
LRRTNARLAPPGEEGSTGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLDLLVDQPHSL-LSILDAQTWLSQVRP-----
-----------------------RSRCCPGWSA-----VVRFRLTTSSAYRATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFGAFLA-RFQALGSEGQED
LSDREKCGTILSQVLGAKSPLCHLGATKV--LLQEQGWQQLEELRDQQRSQALVNLHRSF
HTCISRQ--R--V--LPRMQARM-RGFQARSASIGARAEVGVVRPLDS----SFC---PH
-PLPASRKRCLRRRAALGQLNTMLLVAQPLLR--RRQRLQLG----HWQGWHSSERALER
VPSMELGRLEIPAELAVMLKTAEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LVKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCQPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDTWQDLAGCDFVL
DLISQTEDLGD----PAAPHSYPITPLGST-------------------EAIPLAPGIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVMSSGLSDLEQSWALSSRMKGGGAVGPTQQG-YPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAVVVPPQP-----P---LPSLDAGQLAIQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQQQ-RQRQARASEA--------A------SQASPSAIASK
PRKPP--------TPLEKPQH--DLESEGG----------CLRET-SE-EAEDRPCRPKS
FQQKRNYFQKM---GQP----QITVRAVKPPAKVQIPQGEAQEEEEE-----EQ------
-EEQEVETRAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
GGGQG-----------PAQGM-GIVVRSSDPKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKTFLKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SSSPGKGPPPAVAPRPKTPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEEPGTLSAERRCLTQPMEDQGVSTQLLAPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLDSL
TTTEDGVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRMLAHDPGLEVGAGGK
------VTPA--HARPLR--SFAEVLGVECRGSSTLQLSLKSEQLVLHTARARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
WHKGQLSNGELGLARWDRASERPAHPWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMQE
FALLF-PTERAL-------PGQTDGGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLALMRFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3251)

LLYELLKLCQE-EKLRDEIYCQVIKQVTGHPRL
EHCTRGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRWMLPPGE

ENSGT00920000148963_7_Linker_5_6 (3251, 3354)

MKAFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFTLFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3458)

HFDNSIY
ISTHYSQVLRDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NTP-SEQDLLAYVPQQ
LQ----RQVNMASIKNLMGQELRQLGGHSPQEAQISFIGGSG--A------------GTQ
SEFLPAPSPPAEAVSQLPLFGYTVYVALRVSMQALSGPALLGLNRQHLILMDPSS-----
---QNLYCRIALKSLQRLHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------SEATSVTTYSSLSADSHNYTMRE
FALRYFRKPHTW-------LTQMSAGTKETTVVSLIQYTK----DPIQESLTIFCNEDTN
TKAVAGFKALMQFMGDQPKPRGKDELALLYELLK

PF00784 // ENSGT00920000148963_7_Domain_5 (3155, 3253)

LCQ--EDLRDEMYCQVIKQVTGHPQP
KHCALGWSILSLFTGFFAPSTTLMPYVTKFLQDSS-----PSQELAQSSQENLQRTVKYG
GRQQLPLPGEMH

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQASRLLLIHLPGGVDYRTNTQTFTVAGEVLEELCGQMGITDLE
EVQEFALFIIKG----EGELVRPLSTPEYINNVIKD-QDISLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDNTTY
IETHYGQVLRDYLQGKLIMSAQ--AEAQLAQLAAFQHLSKAS--TGPPSEPELLSYIPKP
LQ----GQVNTASIKSLVIQELRQMQGYNEQKAQIGFIE---------------------
------------TTTQLPLFGHTVYVVLRVSKLALPGPVLLGLNRQHLVLMDPSS-----
---EKLCCSIALKDLQRLHLMSPLEEDGPPGLELNYGSADNPQTIWLELPQAQELQHTII
FLLGS---VST---QWPGL--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MELGRLEIPAELAVMLKTAEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LVKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQ

PF00784 // ENSGT00920000148963_7_Domain_3 (1795, 1900)

RQTMGT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMEALCQHKLLGALEQSQLAPGATRAHPPTQL

ENSGT00920000148963_7_Linker_3_4 (1900, 2895)

EWMAGWRRGRM--------VL
DMFTFSEECYSAEVESWTTGEQLAGWILQSRGLEVPPRGWSVSLHSRDTWQDLAGCDFVL
DLISQTEDLGD----PAAPHSYPITPLGST-------------------EAIPLAPGIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVMSSGLSDLEQSWALSSRMKGGGAVGPTQQG-YPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP-----P---LPSLDAGQLAIQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQ---RQRQARASEA--------A------SQASPSAITSK
PRKPP--------TALEKPQH--DLESEGG----------CLRET-SE-EAEDRPCRPKS
FQQKRNYFQKM---GQP----QMTVRTVKPPAKVQIPQGEAQEEEEEEQE--EQ------
-EEQEVETRAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETVAK
GGGQG-----------PAQGR-GIMVRSSDPRP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKTFLKKIDPKDEALAKL-----------G-----INDA
HSSPPML--SSSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPVPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLAPSASVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLDSL
TTTEDGVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRGLRL---LKVTQASS
------LRPH--QLKILCSYSFAEVLGVECRGSSTLQLSLKSEQLVLHTARARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3145)

PAAAPDFSFSKEQRSG
WHKGQLPNGEPGLARWDRASERPAHPWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMQE
FALRYFRKSQAL-------PGQTDGGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLALMRFMGDQSKPRGKD

PF00784 // ENSGT00920000148963_7_Domain_5 (3145, 3250)

EMDLLYELLKLCQE-EKLRDEIYCQVIKQVTGHPRP
EHCIRGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQHTVKYG
GRRRMLPPA

ENSGT00920000148963_7_Linker_5_6 (3250, 3354)

EMKAFLKGQATRLLLIHLPGGVDYRTNIHTFTVAAEVQEELCQQMGITEPQ
EVQEFVLFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDNSIY
ISTHYSQVLWDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NTP-SEQDLLAYVPQQ
LQ----RQVNMASIKNLMGQELRQLGGHSPQEAQISFIE---------------------
------------AVSQLPLFGYTVYVALRVSLQALSGPALLGLNRQHLILMDPSS-----
---QNLYCRIALKSLQRLHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------T

PF00063 // ENSGT00920000148963_7_Domain_0 (819, 1533)

FGGPLLLALNPHRALPLYAPEV
LASYRPGKTPNTTPHIFAVVASAYS-LSESTGQATCILLGGHSGSGKTEAAKKMVQFLHS
LEWEQTRERGCRLDTVLPLLSSFGHAKTVLNANASRFGQVLCLCLQCGVIVGASASHHLL
ETSRVVFQAQAERSFHVFYELLAGGDPVEREQLSLQGPETYYYLNQ-GRACSLQDKDDAQ
DFRGLVSALQALGLCTEELTAVWAVLASILQLGNICFSSLERESQEVAAVSSWAEIHAAA
RLLRVPPERLEGAVT----RRVTETPYGQVSRSLPMESAIDAR-DTLAKALY-ARLFTWL
LRTANARLASPAEAGSTVTISVVDVYGFEALRV--NGLEQLYNNLGSERLQLWYNRLLLA
QEEEECRRELLPWVPIPQ----ALQESCLDFLVDQPHSL-LSILDAQTWLSQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGDHPCYTKPQLPLPIFTVRHYAGTVTYQVHKFLNRNRDHLDPAVVEMLAQSQLQL
VSRLFQE-----------AEPDEFGGRPGKPTLAARFQKSLGDLLAQLGRRSHVYFIQCL
SPNPGKLPGLFDVDHVAEQLRQAGILEAVCTRSANFPIRLPFQAFLD-RFRALGTEEQGE
LSDRERCGIILNQVLAAESPLCHLGATQV--LLREPGWQQLEQCRAQQRAQALLTLHRGL
RVCISHQRLR--L--LPRKQAHV-RGLQA-------------------------------
------RKRYLRRRAALGQLNTIVLAARPLLW--RRWRPQLG----RRRSWHSIG-AFET
VPSMELGRLEIPAELAAMLKTAEGRQHTRVQSITEAMPPEVPARPSLTLPPDINQFPFSS
FISVGFQEPSLPHPGQL-LTKPLTQLDGENPQHALDINKVMLWLLGDGSLAPWQEQTMGQ
YLVRQGQRRPGL-----------------------------LLLSAFPPMHTLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQTQLDPGSARAHPPTQLEWTAGWRRGRM--------AL
DVSTFSEECYSAEVESWTTGEQFAGWILQSRSLDPPPRGWSVSLHCRDSWRDLAGCDFVL
DLIGQTEDPGD----PARPHSYPIAPRGMT-------------------PTPPPPPAIQA
PSLPPGPPPGPAPTL-PSK-GRTG---------------------DSRT-SG-SLDGFL-
--DHLFEPVLSPGLSDLEQGRALTGRMKGGGAMGPMQQGSYPM-GECGMVQMPS-QPAM-
---MPAPMPMMPAMGPVPDTPAMVVPPQP------QPVLPSVDARQLAAQQQDFINQQAR
ILAQQMTTQAMTLSLEQQAKQLR-QIAPATAPAP------AP---RAASPTSPPPAITHK
PKKTP--------THQKEPES--GLELVGA----------RLTQEAPQ-EAEDRHPRPRS
FQQKRDYFQKL---GQQ----PSKVKTTKPPAKVAIPQAEAVQDEEPEEEEERA------
----------GP-SPPPPPVLKKLPPSRGA------------ARAAQEAEAEPATELGPG
RGHSP-------------AGG-KAVVRSSDPEP-CRAEPSREIRNIIRMYQSRP--GPVP
V-----------PVQPAR-KPPQSFLKKNNPKDEALAKL-----------G-----INGA
SSPPQTL--SPSPGKAPPPPVAPRPRARPRLMPSSSIKEKQGPLQELFGQNPPMPRKL--
-----PPPPAPPLPPPWEPASPPAESRSLVEPMGDEGVSTQLLVPSGSVCFSYASAPWRL
FLRKEVFYPRENFGHPYCLRLLCEQILRDTFAESCIRISQDERRKMKDLLGDLEVGLDSL
DMAEDGVKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLAVSHRGLRL---LKMTQGPS
------LHPD--QLKTLCSYSFAEVLGVECPAGSTLELSLRSEQLVLHTARAGAIKAMVE
LFLSELNAHLQDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FQRGDLIKLLPVAPLEP----------
------------------------GWQFGSTGGRSGLFPADVVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3145)

PAAGAEEQ--------
-----P----GAQGEWDRASEFPTHPWSQARSDNSA-TSLSPSP---ALPT-DSDYTMQE
FALRYFRKPQTL-------PAQTSGDAE-KATASLVQYSK----APIQKSLISFSDEDTN
RQAVESFQALMQFMGDQSKPRGKN

PF00784 // ENSGT00920000148963_7_Domain_5 (3145, 3244)

ELDLLYGLLKLCQEKEDLRDEVYCQAIKQVTGHPRP
KLCARGWRFLSLLTGCVPPSNTLMPYVTKFLQDWG-----PHQELAQSSQEHLQRTVKYG
GRR

ENSGT00920000148963_7_Linker_5_6 (3244, 3355)

AL-------SWQKGQVVHLVLIHLPGGVDYKTNIRTFTVAAEVLEELCRQMGITDPQ
EVQEFALFLIKG----DSELARPLWPQEYLNSVLGG-PDVSLHSRRLGWGTQLH

PF00373 // ENSGT00920000148963_7_Domain_6 (3355, 3505)

FDNPTY
ISTHYSQVLRDYLQGKLGLSPQ--EDTRLARLAALQQLSRNKE-EPP-SEQDLLAYLPRK
QQWQQQWQMNVATVKSLMGRELRQLQGYSSQEAQISFIK---------------------
------------AVSELPLFGYTVYPVLRVSNPALPSPGLLGLNRQHLVLMDPSS-----
---QELCCSIALRDLQRPRLQGPTEGEGP---PLNYGSADNPQTIWFELPQVGGLRV---
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------RCPPHCHMCPG------------A
AGE-------------------WPGATVQQPRQRAPAAL-L-PEAAGPGGGGVSAGAAAL
GAHRAASAGVLPGPPRGPAPQPPDSPGRPDLVG-----------------P

PF00063 // ENSGT00920000148963_7_Domain_0 (1312, 1486)

ATDHTFLQK
CHYHHGNHPSYAKPQLQLPIFTVRHNAGSVTYQVHKFLNRNRDQLDRAVEELLAQSRLEL
VGSLFQA-----------AEL-RVEDRPGRGTLASRFQHSLSALLMELGR-SHIHVIQCL
SPNPGKFPGLFDVNHVAEQLRQAGVLEAVAARHAHFPVRLPFQVFLA-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------XX-XX---XX-XXXXXXXXX
XXXXXXX-X---X-----X--XX---X----------------XXXXXXXXXXXXXXXXX
XXXXXXXKRYLRRRAALGQLSTMLLVARPLLW-RHRRRRQLG----HWCGWHDGA-ASKK
MPSMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXILRLLGDSALFS

PF00784 // ENSGT00920000148963_7_Domain_3 (1793, 1877)

LHEQALAC
SLVRQGKRRLVLLDEFFTQLMAQLWHNPDEQQSQRGLALMNVLLSTFPPTPALQKQLLKF
VSDHAPHGMAALCQHK

ENSGT00920000148963_7_Linker_3_4 (1877, 2894)

LLGALEQTPLAPGAARAHPPTQLEWTAGWRRGRM--------AV
DVLTFNEECYSAEVESWTTGEQLAGWILQSRGLETPPRGWSVSLHSGDAWQDLAGCDFVL
DLIGQTEDLGD----PAQPRGYPIAPTGL-------------------AEDIPPAPGVQA
PTLPPGLPPGPAPTL-PGG-GLTG---------------------ETRP-PG-SLEGFL-
--DNLFEPVFSPGLRDLEEGWALSSRMKGGGGIGTPQA-GYPL-VYPGMMQVPSYQPA--
-M-IPTPMPMMPAMGTVPTMPAMMVPPQPQ----PQPLLPSLYTRQLAAQQQNFINQQAM
IAQQPNFQTTKAMILLQDGMGPGGPIWWQQ------------RVAPRAVSQAPPPAVTPK
PKKPP--------TPRVEPKQ--DPEPVVV----------SLREEPPEEDVPDGFWRPKS
FQQKRDYFQKM---GQQ-----QVIKKVKPPAKIEIPQGEEEEEEEEQ------------
----------VPAPPPPPPVTK-KPLKQSK------------HKATKEAEAEPAKPVPAP
APPP-----------PPVPRR-EPAVHNVSPTS-QRPEPSREIRNIIRMYQSRP--GPVP
V-----------PVEPS--RPPKTFGKKNDPKDEALAKL-----------G-----IHGA
HSPPAML--SPGLGKEPPPAVAPRPKDSPRPGPSSSIRAKQEPLRDLFSQNRLIANAP--
-----PPLPAPPLPPPEDSRTLSTKPHGLLEPMRDQGLSTQLLASSGSVCFSYTSAPWRL
FLRKEVFYPRENFSHPYSLRLLCEQILRDTFTESCIRISPEERSRMKELLGDLEVGLDSL
GTAEDSVKKRIVVAARDNWANYFSRIFPVSDGHGSDVQLLGVSHRGLRL---LKVTPGPN
------MHLN--PLKTLCSYSFAEVLGVECRGVSTLELSLTREQLVVYSARAQAIKALEE
LFLNE---LKEDS

PF00018 // ENSGT00920000148963_7_Domain_4 (2894, 2986)

GYVV-ALRSHITDDRSLLS-FHRGDLIKLVPVASLEP----------
------------------------GWMFGSAEGRSGLFPGNLVQPAAAPDFSFSEQPGN-
-RRRRSQLGEPGLAQWSRVSEVRKSREAE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GHQACVLAPLAAPDPP-PHVGAHLT-AHV----
----PPGLAAPA--------AVVQP---AAARPGGGGVSEGVAALGAHP-----------
----PGPAGVLPGLPGRPATQPPEYPGCPDMAVPGEPLVRTGRGLSISS

PF00063 // ENSGT00920000148963_7_Domain_0 (1250, 1534)

SHQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGDHPCYTKPQLPLPIFTVRHYAGTVTYQVHKFLNRNRDHLDPAVVEMLAQSQLQL
VSRLFQE-----------AEPDEFGGGPGKPTLAAHFQKSLGDLLAQLGR-SHVYFIQCL
NPNPGKLPGLFDVDHVAEQLRQAGILEAVCTRSANFPIRLPFQAFLD-RFRALGTEEQGE
LSDRERCGIILNQVLAAESPLCHLGATQV--LLREPGWQQLEQCRAQQRAQALLTLHRGL
RVCISHQRLH--L--LPRKQAHV-RGLQA-------------------------------
------RKRYLRRRAALGQLNTIVLAARPLLW--RRWRPQFW----SIAP----------
-LHQELGRLEIPAELAAMLKTAEGE------SITEAMPPEVPARPSLTLPPDINQFPFSS
FISIGFQEPSLPHPGQL-LTKPLTQLDGENPQHALDINKVMLWLLGDGSLAPWQEQT

PF00784 // ENSGT00920000148963_7_Domain_3 (1798, 1903)

MGQ
YLVRQGQRRPGLRDELFSQLVAQLWRNPDEQQSQRGWALMAVLLSAFPPMHTLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQTQLDPGSARAHPPTQLEWT

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVSTFSEECYSAEVESWTTGEQFAGWILQSRGLDPPPRGWSVSLHCRDSWRDLAGCDFVL
DLIGQTEDPGD----PARPHSYPIAPRGLM-------------------GLQEAPP----
---------------------SVG---------------------ESRT-SG-SLDGFL-
--DHLFEPVLSPGLSDLEQGRALTGRMKGGGAMGPMQQGSYPM-VYPGMVQMPSYQPAM-
---MPAPMPMMPAMGPVP---AMVVPPQP------QPVLPSVDARQLAAQQQDFINQQAR
ILAQQMTTQAMTLSLEQQAKQLQ-KQSQALALAP------AP---ATAPVRV--------
--GAL--------CERQLGQQ--GCSFCSP----------SCQQEAPQ-EAEDRHPRPRS
FQQKRDYFQKL---GQQ----PSKVKTTKPPAKVAIPQAEAVQDEEPEEEEERA------
-GSEEAGGRLGP-SPPPPPVLKKLPPSRGA------------ARAAQEAEAEPATELGPG
RGHRP-------------AGG-KAVVRSSDPEP-CRAEPSREIRNIIRMYQSRP--GPVP
V-----------PVQPAR-KPPHSFLKKNNPKDEALAKL-----------G-----INGA
SSPPQTL--SPSPGKAPPPPVAPRPRARPRLMPSSSIKEKQGPLQELFGQNPPTAQKL--
-----PPPPAPPLPPPWEPASPPAEPRSLVEPMGDEGVSTQLLAPSGSVCFSYASAPWRL
FLRKEDRV---------VTAWLAPQILRDTFAESCIRISQDERRKMKDLLGDLEVGLDSL
DMAEDGVKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLAVSHRGLRL---LKMTQGPS
------LHPD--QLKTLCSYSFAEVLGVECPAGSTLELSLRSEQLVLHTARAGAIKAMVE
LFLSELK---KDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FQRGDLIKLLPVATLEP----------
------------------------GWQFGSTGGRSGLFPADVVQPAAAPDSFFSTEQRSS
QGHKGQ----LQRREWDRASEVRKTGEAKARPQ---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------PFQSLLFLTK----ATIQESLISLRNKKTS
RRAVESFQVLMQFMGDQPKPRG

PF00784 // ENSGT00920000148963_7_Domain_5 (3143, 3255)

KDEIELLYELLKLCREKENLRDEIYCQAIKQVTGHPRL
EFCARGWSFLSLLTGFLPPSTTLMPYVTQFLQDAG-----RSQELARSSQKHLQQTVKYG
GRRRLPPPGEMKAFLKGKMLRLLLVHLPGGVGYKTNVGTFTVAAEVLEELCGKMGITEPE
EVQEFALFLIQG----EGELARPLRPQEYLNNVLVD-PKTSLHSRRLGWETRLHFDNPTY
ISTHYSQVQRDYLQGKLLVGAQ--ADAQVARLAALQLVSRTQE-APP-SERDLLAYLPRL
LQ----GQVNVAAIQSLMDQELRQLQGCSAQEAQIGFIE---------------------
------------AASQLPLFGYTVYVVLRASDLTLPRPSLLGLNRQHLILMDPSS-----
---QTLCCSIALRDLQQLHLLSPLEAGRPPALELNYGSADSPQTIWFELPQARELQYTIA
FLLNSS---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------DSEATSLQSSTVYTSLSTDSHNYTMQE
FALHYFRKPLTL-------LDLTGGGTRAKAMASLVQWSKVRG-APIQESLIRLSDENMS
KRAVVGFEALMQFMGDQSKPRGKDEMDLLY

PF00784 // ENSGT00920000148963_7_Domain_5 (3151, 3253)

ELLKLCQG-EDLRDEMYCQVIKQVTGHPQP
EHCARGWSLLSLFTGFFPPSTTLMPYVTKFLQDSG-----PSQELARRSQQHLQHTIKYG
GRQRLPQPGEMR

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRQLLIHLPGGVDYRTNLKTFSVAGEVLEEMCGKMGITDPQ
EIQEFALFLIK-----GGELVRPLWPHEYLNSVVVG-QDTSLHSQRLSWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPIY
IGTHYGQVLRDYLQGKLMAHAQ--ADAQLAQLAALQHLGRASK-SPP-SEQDLLGYIPKT
LQ----WQVNMATIESLMGQELRQLQGHSSQEAKISFIE---------------------
------------ATRQLPLFGYNVYVVLRVSNLVLPGPVFLGLNRQHLVLMDPTS-----
---QKMCCSIALKDLQRAHLLSPLKVNGPPGLELNYGLADSPQTIWLELPQAQELLRTII
FLLD-GSVSSTQP-RWPGLI-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MEQRS
GRRKSQ----LQRGEWDRASEAHSDTS----------------ATYVALPTDSHDYTMQE
FALLYFRRPQTL-------LGQT-GEAERKAMASLVQFSK----VPIQESLLSFSDEDMN
QQAVKSFQALMQVMGDQPKRWGKDEL

PF00784 // ENSGT00920000148963_7_Domain_5 (3147, 3253)

DLIYGLLKLCREKDNLRDEIYCQAIKQVTGHPRP
KHCARGWSFLSLLTGYVPPSATLMPYVTKFLQDSS-----LSQELARSSQEHLQRTVKYG
GRRRLPSLSEMR

ENSGT00920000148963_7_Linker_5_6 (3253, 3355)

AFLKGHVIHQLLIHLPGGVDYKTTIRTFTVAAELLEELCRQMGIGDPQ
EVQEFALFLIKG----DGELVRPLWPQEYLNSVL-D-KDVSLHSRRLDWETQLH

PF00373 // ENSGT00920000148963_7_Domain_6 (3355, 3505)

FDNPTY
IGTHFSQVQRDYLQGQLLVSAQ--ADAQLARLAALQHLSKGLE-EPP-SEQDLLAYLPKQ
LQ----WQVNLTAIKSLIGQELKQLQGCSSQDAQISFIE---------------------
------------AARVLPLFGYTVYTALRVSRPGLPSPSLLGLNRQHLILMDPSS-----
---QQVCCSIALKDLQRMHLLSPMEAEGSPGLELNYGPAASPETIWFELPQAQELKHTIA
FLLDSEP-----PSP------

MGRNQGKTPQHLARPGRPASGEQESGSASADG-GPSQERRSDRGQVVRARPAAEPATAGG
QGTAGGRRKLTAEENGGCRRPGAGSPPEAQERQGSAGRQGRGPRGGR------RGRLE-G
SLSRGEGR----SGRRRRKGKDRGPSAQRGRRAPRSLDGDTSGGNGGSSCPDSEAREAQE
SGSQRGGARELRPTLEPTVTGSEGTKTGPESA-LE---PSSDGLDSDWPRADPWG-RERS
SGTGPLGASEHSGGDSDSSLLETGPGRGPRAAM--ASRT-----FEG--------S----
---SQAPRNTGPAQDASDNRAQ-----RGAKPETMQALTARAPRHPVGKAAGRVPAAAGE
GEAGAPAGA-----GPEDPAPLAALLVVRRLFARSPPGAASQAVGPSRAGLKERLLNVAR
ALGLLRWLRRRLRLRPRQPEGKRQGAGPRASEG---------------------------
-----------------------------------------------------------G
DEGRR-PEPGLRYRLALRLA-GLAGLG-TPRAPPGVLSRPPQVRTSPVPDD-TFDQEDGT
PDPKFAVVFPRIHRAGWASSSRSSEEA--STDAPTGEGRGWPRAGAGGHS--EERRASGE
GVSGLRRGSLLAPTAPDGPSLDESGSSSEAESEILDDEPPVHWAQGSGPRKGPRLGA-AV
LLPRLALETRLQQEGDPGLRGSLRERWEPEDEDEAVLERDLELSRGPGLEAPPFPGAEGR
SLEDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1533)

HIFAIVASAYD-LAQHTGQDPCILLRGHSGSGKTEASKKIVQFLSS
LEQDQTGNRGCQVEDVLPILNSFGHAKTILNANASRFGQVFCLYLQQGAIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACSLQGKEDAQ
DFEGLVKALQGLGLCPEELNAVWAVLAAVLQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPVEGAIDAR-DALAKALY-SRLFHRL
LRRTNARLAPPGEGGSIGTITVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLDLLVDQPHSL-LSILDAQTWLSQTE------
-----------------------FGSCCPGWSA-----MVRSWFTATSTSEATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVHKFLHRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFEAFLASRFQALGSEGQDD
LSDREKCGSILSQVLGAKSALCHLGATKV--LLQEQGWQRLEELRDQQRSQALVNLHRSF
HTCISRQ--R--V--LPRMQARM-RGFQARSASIGARAEVGGVRLLDS----SFR---PR
-PLPASRKRCLRRRAALGQLNTILLVAQPLLR--RRQRLQVQ----GLGGG--QRRVEAR
LPELELGRLEIPAELAVMLKTVEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LAKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDTWQDLAGCDFVL
DLISQTEDLGD----PAAPHSYPITPLGSA-------------------EAIPLAPSIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-PG-SLDGFL-
--DQIFQPVMSSGLSDLEQSWAVSSRMKGGGAIGPTQQG-YPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQL-----P---LPSLDSGQLPIQQQTFINQQAL
ILAQQMTAQAMTLSLEQQTQQ---RQRQAQASEA--------A------SQASPSAITSK
PRKPP--------TPLEKPQH--DLESEGG----------CLRET-SE-EAEDRPCRPKS
FQQKRNYFQKM---GQP----QITVRTVKPPAKVQIPQGEAQEEEEEE----EH------
-EEQEVETRAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
GRGQG-----------PAQGR-GIVVRSSDPKS-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKAFPKKINPKDEALAKL-----------G-----INGI
HSPPPML--FPSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLAPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLGSL
TTTEDGIKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRALAHDPGLEVGAGGK
------VTPA--HARPLR--SFAEVLGVECRGSSTLQLSLKSEELVLHTARARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
WHKGQLSNGEPGLARWDRASERPAHPWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMRE
FALLF-PRGSAL-------LGQTDGGATGKDTDSLVQYTK----APIQESLLTLSDD-VN
KLAVASFLALMRFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQE-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRWMPPPGEMK

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFALFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLSWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3458)

HFDNSIY
ISTHYSQVLRDYLQGKLPVSAK--ADTQLARLAALQHLSKANR-NTP-SEQDLLAYVPQQ
LQ----RQVNTASIKNLMDQELRQLGGHSPQEAQISFIGGSG-----------------Q
SEFLPAPSPPAEAVSQLPLFGYTVYIALRASMQALSGPALLGLSRQHLILMDPSS-----
---QNLYCRIALTSLQRLHLLSPLEETGPPGLELNYGTADNPQTLWFELPQAQELLYTTV
FLIDSNA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MQE
FALRYFRKPQTL-------LGQTSEDAKRKAMASLVQYSK----APIQASLISISDEDVN
RRAVGSFQXXXXXXXXXXXXXXXXXXXXX

PF00784 // ENSGT00920000148963_7_Domain_5 (3150, 3255)

XXXXXLCQ-EENLRDEIYCQAIKQITGHPRP
RRCARGWTFLSLLTGYFPPSTSLMPYVTKFLQHSA-----LSQELARRCQGHLQHTVKYG
GRRQLPSPGEMQAFLKGQVVHLLLIHLPGGVEYKTNTHTFTVAAEVLEEMCGQMGITDPH
EVQEFALFLIKG----EGQLVRPLWPREYLNSEVVG-LDVSLHSRRLGWETPLHFDNPTY
VSTHYGQVLRDYLQGKLLVSAQ--EDARLARLAALQHLSRNHE-EPP-SEQDLLAYLPKQ
L----QCQMNVAAVKSLMGQELRQLQGCSSQEAQISFIE---------------------
------------AVSELPLFGYTVYMVLRVSKPALPSPGLLGLNRQHLILMDPSS-----
---QDLCCSIALRDLQQLRVLSPLGPEDSPGLELNYGSADNPQTIWFELPQAQELKHTIT
FLLDRNS-----PSTWPGFTQ

MGGSKGKAPQRRPRPGRPASAERESGSASADCCAPSRDRRPARSKARKNKTATEHEATGG
KGTAGGQRKHTGEGNHRCRSAETGTSQETQEKQGSSQRLRHGPTESRDSGDSCGEHTEEQ
RIPREEERTGKRGRRRR--GKDRGPLTRRGHGETPGRDGDTSGGDGGSSCLDSEAREAQD
SSSQGGGAPERPPKMEPSDPSSEGAPVRGSSSTLVQG-----NHPGSEGHALELQSNEGS
SGMGPQRASDDSRTDTDSNPGWAGHRHLPQKIP--GTSSGIPESQEIELGSEAAAS--SV
PRGSQSPQDSSAIVDTSDVGAQPKAELLGTEPETAG--APGAQLLQVGEVTRKALVVAGE
SDGGARERSGAGDPGPRDRTPLAALVVLRRLRPRPPAGASPQFAGGIRVGLKARLQRVAR
TLGFLRWLRLRVERR----RTEARAPSPREC-----------------------------
----------------------------------------------------EERGRERA
LEARG-RVPGPRRWLALRLACRLVGLRGTPRALPGGGPSPPQALSSSVSND-ASAIEDPA
PDPKFAVVFPRIHNAGKESGSSSS-GT--SADAPTAE-A-------AEDR--EEQEANGE
GVVRSCQGPSFFPSE---TPPDEN--RSEAETETLEAKTGVHWAQDSNPSEDPELGA-DT
LLPQLTLETRLR-QNSP--CRSPRERWEPEDDTEAALERDLELSLQRNLEMPPFLGAKTG
SLPEGLEDI

PF00063 // ENSGT00920000148963_7_Domain_0 (790, 1533)

EDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPLLLALNPHRSLPLFSSEV
LASYHPRKAPNTTPHIFAIGAAAYS-LSQSTGQDSCILLGGHSGSGKTEGAKKILEFLSS
LGQKPMEANRAQLEDILPVLGSFGHAKTILNANASRFGQEIRLCLQQGLIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDPTEREQLSLQGPEAYYYLNQ-GGACRLQGKEDAQ
DFKELMKALRGLGLCAEELTEVWAVLATILHLGNICFSSSERESQEVAAVSSWAEIHLAA
RLLQVPPERLEGAVT----KRVMDTPYGPVSRPLPVEGAIDAR-DALAKTLY-TRLFTWL
LKHINARLSPPREEDNVATIAVVDAFGFEALRV--NGLEQLCSNLASERLQLFSSQKLLA
QEEEACQQELLKWVPIPQ---P-PRQSCLDLLVGQPHSL-LSILDTQTWLSQ--------
---------------------------------------------------ATDHTFLQK
CHYQHGDHPSYAKPQLPLPIFTVRHYAGTVTYQVHKFINRNRGHLDPAVLEMLRQSQLQL
MGSLFQE-----------AEP-QAGTEQNKPTLASRFQQSLGDLLARLGR-GHVYVIHCL
NPTPGKLPGLLDVGHVAEQLRQAGILEIIVTRSAHFPVRVSFQVFLA-RFHALGSGRQKA
ASDQERCGAVLSEVLGTESPLYHLGVTQV--LLQEQGWQQLEQLWAQRRSQALLTLHRGL
RACITRQRLR--L--LPRMQARV-RGLQA-------------------------------
------RKRYLQRRSALGQLNTILLVARPLLR--RRQKLR-------CAPGPHSREPWGK
VSNMDLGRLEIPAQLATLLERAEDHQALLTGSITESLPPEVPARPSLTLPPDIDQFPFSS
FVSTSFQKPFLPRPGQP-LDEPLTRLDGENPQQALEINRVMLRLLGEGSLQSWQEQTMG

PF00784 // ENSGT00920000148963_7_Domain_3 (1800, 1903)

T
FLVQQAQRRPGLRDELFSQLVAQLWRNPDEQQNQRGWALMVILLSSFAPTPALEKPLLKF
VSDQAPSGMAALCQHKLLGALEQTPLAPMASRSHPPTQLEWK

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGLRRGRM--------AL
DVFTFNEESYSAEVESWTTGEQFAGWILQSRGLESPPRGWSVSLHSGDAWRDLPGCDFVL
DLIGQTEDLGD----PAGPHNYPIAPLGLA-------------------ESIPPAPGVQA
PSLPPGLPPGPAPIL-ASS-RPPG---------------------EASK-PG-NLDGFL-
--DHLFEPALAPGFSDLEQGWALSRRMKGGGSVGPTQ-QGYPM-VYPGMVQAPNYQPAM-
---IPAPMPVIPAMGTVPTMPAMMVPPQP------QPLVPSLDSRQLALQQQNFINQQAM
ILAQQMTTQAMSLSLEQQNQRRQ-HQAQT----------------SGATSQPPPSTTAPK
AKKPP--------VPQEKPES--NLEPSGV----------CLREDTPE-EAESRPQRPKS
FQQKRDYFQKM---GQE----PIRVKTVKPPAKVQIPQEETEEEEEEEEEEEEE------
-EE---TAELSP-PPPPPPVMK-KPLKSSR------------PKAVKEDEVEPAQEEVPT
QGEDPPVHSSKSAPQHPKPSR-APPVQSSNSAP-PRPQPSREIRNIIRMYQSRP--GPVP
V-----------PVQPTR--PIKTFQKKNDPKDEALAKL-----------G-----INGV
HLPL-ST--LPNQGKSSPPAVVPRPKARPRLEPSLSIREKQGPLRDLFGPCSPNPPAAPA
PPPP----PALPPPLSGEPKTPSVESHALAEPMEDKNISTKLLVPSGSVCFSYANAPWKL
FLRKEVFYPRENFSHPYCLSLLCQQILRDTFTESCTRISQDERHKMKGLLGDLEVSLETL
DVVEDSVKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTQSPS
------FHLD--QLKTLCSYSYAEVLTVQCRGRSTLELSLKNEQLILHTAWARAIKAMVD
LFLSE---LRKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDNSLLS-FHRGDLIRLLPVTALEP----------
------------------------GWQFGSAGGRSGLFPDDVVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3156)

PAAAPDLSFSLGKRNS
WQRKSKLG--------P-AQERPTHPRKQ---EPSEDSEATSFTTYSSLSADPHNYTMQE
FALRYFRKPHTW-------LTQMSGDTKEKAAINLIQYTK----DPIQESLTSFCNGDTN
SKAVAGFKALMQFMGDQPKPRGKDELTLLYELLKL

PF00784 // ENSGT00920000148963_7_Domain_5 (3156, 3253)

CQ--DDLRDEMYCQVIKQVTGHPQP
KHCALGWSVLSLFTGFFAPSTTLMPYVTKFLQDSS-----PSEELARRSQENLQRTVKYG
GRQQLPLPGEMN

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRLLLIHLPGGVDYRTNSQTFTVAGEVLEELCGQMGITDLE
EVQEFALFLIKG----EGELVRPLSSHEYINNVVTD-QDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPTY
TETHYGQVLRDYLQGKLIVSTQ--AEALLAQLAAFQHFDKTGT-TSPPSEQELLSYIPKP
LQ----WQVNTANIKSLVTQELRQMQGYSKQRAEIGFIE---------------------
------------STAQLPLFGYTVYIVLRVSKLALPGPILLGLNRQHLVLMDPSS-----
---QKLCCSVTLKDLKRLHLLSPLQEDGPPGLELNYGPVDNPQTIWLELPQAQELQHTIV
FLLGS---TST---QWPGLL-

MGRNQGKAPQRLARPGRPASGEQESGSASADG-APSQERRSDRGQAVRARPAAQPATAGD
QGTAGGRRKPIAEENGGCRRPGAGSPPEAQERQGSARREGRGPRGGR------RGRLEEG
SLSRGEGR----GGRRRRKGKDPGPSAQRGRRAPRSLDGDTSGGDGGSSRPDSEAREAQE
SGSQRIGARELRPTLEPRVTGSEGTKTGPESA-LE---PSSDSLDSNWPRADPWG-REGS
SGTGPLGASEHSGDDSDSSLLETGPGRGPRAAM--ASRT-----FEG--------S----
---SRAPRDTGPAQDACDNRAQ-----RGAKPETMQASTARAPRHPVRKAAGRVPAAAGE
GEAGAPAGV-----GPEDPAPLAALLVVRRLLARSPPGTTSQAVGPRRAGLKERLLSVAR
ALGLLRWLRRRLRLRPRPPEGEGQGAGPRASEGWGRGKAYEGRG---------RGKADDG
LGHGRGSEGRGHERG------------------------------------DEGRDHERG
GEGRG-PEPGLRHRLALRLA-GLAGLGGRPRAPPGVLSRPPQVRTSPVPDD-PFDQEDGT
PDPKFAVVFPRIHRAGRASSSRSSEEA--STDAPTGKGRSWPSAGAGGHS--EGRRASEE
GVSGLRRGSLLAPTAPDGPSLDESGSSSEAESETLDDEPPVHWAQGSGPRKCPRLGA-AV
LLPRLALETRLQQEGDPGLRGSLRERWEPEDEDEAVLERDLELSLGPGLEAPPFPGAEGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1119)

HIFAIVASAYD-LAQHTGQDPCILLRGHSGSGKTEASKKIVQFLSS
LEQDQTRNRGCQVEDVLPILSSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFEGLVKALQGLGLCPEELNAIWAVLAAILQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRSLPMEGAID-------------------
-----------------------------ALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-PRESCLDLLVDQPHSL-LSILDAQTWLSQTE------
-----------------------FGSCCPGWSA-----MVRSRFTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFGAFLASRFQALGSEGQEG
LSDREKCGTILSQVLGAESPLCHLGATKV--LLQEQGWQRLEELRDQQRSQALVNLHHSF
HTCISRQ--R--V--LPRMQARM-RGFQARSASIGARAEVGVSCSVT-------------
-QPGAQWKRCLRRRAALGQLNSILLVAQPLLR--RRQRLQLG----HWQGWHSSERALER
VPSMELGRLEIPAELAVMLKTAEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FISIGFQEPSLPRPGQP-LVKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSGEGCLS--LKWGQPYP---FAL----------------------PGTPSCPSLP
AALSSVTLFSL-------PSVLLLKPSWGQ-------------------QPLPVRV---D
PAVPHSCPRPPRPYR-GVL-LSRG---------------------GVLD-HR-GAAGWVD
PAEQVWRPGMGDSVAKVIIVPPVS-GAGRGGALGWAGAR-LQM-AMGSQDSHDPDSNSW-
---AESFWPWCPPLWPPAALTAMVVPPQP-----P---LPSLDAGQLAIQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQ---RQRQARASEA--------A------SQASPSAITSK
PRKPP--------TPLEKPQH--DLESEGG----------CLRET-SE-EAEDRPCQPKS
FQQKRNYFQKM---GQP----QITVRTVKPPAKVQIPQGEAQEEEEE-----EQ------
-EEQEVETRAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
GGGQG-----------PAQGR-GIVVRSSDPKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPKTFLKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SSSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLAPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGDLEVDLDSL
TTTEDGVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRVLAHDPGLEVGAGGK
------VTPA--HARPLR--SFAEVLGVECRGSSTLQLSLKSEQLVLHTAWARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHHGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3150)

PAAAPDFSFSKEQRSG
WHKGQLSNGEPGLARWDRASERPAHPWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMQE
FALRYFRKSQAL-------PGQTDEGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLALMRFMGDQSKPRGKDEMDLL

PF00784 // ENSGT00920000148963_7_Domain_5 (3150, 3247)

YELLKLCQE-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRWML

ENSGT00920000148963_7_Linker_5_6 (3247, 3354)

PPGEMKAFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFTLFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3458)

HFDNSIY
ISTHYSQVLRDYLQGKLPVSAK--ADAQLARLAALQHLSKANR-NTP-SEQDLLAYVPQQ
LQ----RQVNMASIKNLMGQELRQLGGHSPQEAQISFIGGSG--A------------GTQ
SEFLPAPSPPAEAVSQLPLFGYTVYVALRVSMQALSGPALLGLNRQHLILMDPSS-----
---QNLYCRIALKSLQRLHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MELGRLEIPAELSALLKKAEGCQHVMTESITETLPPEVSAQDTLALPPDIDKFPFSS
FISKNFQKPTLPTPGQP-LTSPLTYLDGASSQLALDVNKVMLRLLGDISLESWQEQTMGT

PF00784 // ENSGT00920000148963_7_Domain_3 (1801, 1901)

YLACLGQRNPALRNEIFCQLVTQLWRNPDEQQSYRGWALMAILLSAFPPSLTLQKPLLKF
VSDHAPKGIAAVCQHKLLEALQQCQTVANTVRAYPPTQLE

ENSGT00920000148963_7_Linker_3_4 (1901, 2895)

WIAGWRCGRM--------AL
DVFTFSEERYSAEVKSWTTGEQFAGWILQTRGIEQPIRGWSVSLLSGDAWQDLVGSDFVL
DLIGSTEDLGD----PTTPDCYPINSQNTI------------------YKDIPPPPSIQA
PPLAPGPPPGPAPSL-PQK-VPTR---------------------QPQS-PG-SLDGYV-
--DDLFETVLSPGPTDLEQVRALNSRMKGGGGIGTQQ-GAYPM-MYPGMMQMPTYQPPIG
PM-MPAPVPLMPAVGGIPAMPAMMMPSQ------PQPVVPALSARELAAQQQSFINQQAM
ILAQQMTTQAMALSLGQQTQQQPP------------------AQAS--MSPSQPAPRAPK
PKESPAEVRKSTSASKLEPQR--RLESVE---------------A--PDETEEEVNYLNS
FQEKRDFFQKI---GQE----PIRLKTVKPPAKVPIPQGEIKQKEEEEKEEIKGESD---
----------LVERALLLPIIN-LFM-------VFSFQDNIGAKVGDEAKTDISP---GA
KSQK-----------EKERPQ-GTVVRSSKPVS-TRAEPSREIRNIIRMYQSRP--APVP
E-----------PIQPTR-KPQRAFSKKNDPKDEALAKL-----------G-----LSGN
CLPPSAS--ALGPQKTPPPV-LPRTKPTTPSGTSRSIQEKQRPLLDLFAPVPPKTPNP--
-----QPPPPPAPALPESSMIPSAGP---VPSMGDEYISTQLLPPSSSVSFSYASASWRL
FLRKEVFYPRENFSHPYCLQLLCEQILRDTFTESCTQISPEERSKMKDMLVDLKVGMDAS
SITEDSIKKRIVVAARDNWANYFSRIFRVSGESGSDVQLLAVSHRGLRL---LKVVNDAT
------VHTG--HLKTLCSYSFAEVLDVKAQEHGVLQLSLRNEQLILHTSQAQAIKSMVE
LFLNE---LKKDSS

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYVTDNPSLLS-FHYGDIIKLLPMSSLEP----------
------------------------GWQFGSIGGRSGLFPSDMVKVAAASDYLTMPMERKV
EGHRN-SRRESGLSPQKQAMECEHPPSQAPS-EYSGLTSSVFLDVDSTLAASISTYTMWE
YALHHFRPIQTS-------EGWMLDMA-EHSARSLVQHTK----L---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------NSEATSLPSSMAYASLSTDSHSYTMQE
FALRYFRKPQTL-------LDLT-GGAEAKAVASLVQHSK----VPIQESLISLSDEDTS
RQAVTSFKALMQFMGDQSKPWGKN

PF00784 // ENSGT00920000148963_7_Domain_5 (3145, 3254)

ELDLLYKLLKLCQE-ENLRDEIYCQVIKQVTGHPRP
DHCARGWSFLSLLTGFFPPSTTLMPYVTKFLQDSG-----PSQELAQSSQEHLQRTVKYG
GRQRLPPLEEMQA

ENSGT00920000148963_7_Linker_5_6 (3254, 3354)

FLKGQAVRELLIHLPGGTDYKMNIRTFTVATEVLEELCRQMGITEPQ
EVQEFALFLIKR----EGELVRPLRPGEYLNNVMVN-PHVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDNPTY
VSTHYSQVLRDYLQGKLRVSAQ--ADAEIARLAALQHLSKDKK-TP-PSEQDLLAYIPKP
LQ----WGVSVTTIKGLMGQELRQLQGQSSQEAQISFI----------------------
-----------EAMRQLPLFGYTIYVVLRASELTLPGPSLLGLNHQHLLLMDPSS-----
---QKPLCSISLKSLHRLHLLSPQEVGGTPGLELNYGSADNPQTTWFELPQAQELLNTIL
FFLDSTC-S-----RWPGLP-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------AVCALHP--LLCSLHCHAPPG------------A
AGE-------------------QPGAAVQQPGQA-PAAL-LQPDTAGPGGGGMSAGVAFL
GAHPPDSMGVLPGPP-RPAPQPPEYPGCPNVAASXXXXXXXXXXXXXXXXX

PF00063 // ENSGT00920000148963_7_Domain_0 (1312, 1486)

ATDHTFLQK
CHYHHGNHPCYSKPQLPLPIFTVQHYAGTVTYQVRKFLNRNQNHLAPAVVEMLGQSQLQL
VGSLFQE-----------TQS-QPKGRQGKPTLASDFQQSLGELVARLRR-SHVYFIQCL
NPNPGKLPGLFDIGHVAEQLRHSGTLEAIHTRSANFPVRVPFQAFLA-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX-------X--------XX-XXXX-XXXXXXXXXXXX
XXXX----XX--X--XX-XX-XX-X-XX-----------------XXXXXXXXXXXXXXX
XXXXXXXKGYLRRQAALGQLNTILLVARPLLR-RRQ-RLQLG----HWCGWHSSR-AMEK
MPGMELGRLEIPAELAIMLKTAEGRQPALAKTITESMPPEVTARPNLALPPDVDRFPFSS
FISSSFQEPSLPRPGQP-LIKPLTRLDGESPQLALDVNKVMLRLLGDVSLAP

PF00784 // ENSGT00920000148963_7_Domain_3 (1793, 1905)

WQQQAMGA
YLAQQGQQRPGLRDELFSQLVAQLWHNLDEQQSQRGWVLMAILLSAFPPMPTLQKPLLKF
VSDQAPKGMAALCQHKLLGALEQTRLAPGAARDHPPTQLEWTAG

ENSGT00920000148963_7_Linker_3_4 (1905, 2894)

CRRGRM--------AL
DIFTFNEECYSAEVESWTTGEQLAGWILQSRGLEGPPHGWSVSLHSGEAWQDLAGCDFVL
DLIGQIEDLGD----PAAPRSYPITPYTFT------------------PEDIPPAPGVQA
PRLPPGSLPDPAPAL-PSR-GHPG---------------------EAQT-SR-SLDGFL-
--DHLFEPVLSPSLSDLEQSWALRGRMKGGGAIGPMQQSSYPM-VYPGMMQMPGYQPA--
-M-VPAPVPMMPAMGTVPPIPAVMMPPQP-----SQPALPSLNASQLAVEQQTFINQQAM
ILAQQMTTQAMALSLGQQIQQQR------Q------------TRASGAASQQPVAATHKP
RKLPP--------TPQEEPVH--DMEPASA----------FVREEPSE-EAEDSPWYPES
FQQKRDYFQKM---GQQ----KIKVKAVRPPAKLRIPKAEEEEEEEEEEEEA--------
-------RAASPPSPPPSPVVR-KPLKQGG------------AKSASVAEDEPDQAK---
GNKQ-----------GLSKNR-EPVVQSTKPTV-QRPEPSREIRNIIRMYQSRP--GPVP
V-----------PVQPS--RPLKTFLKKNDPKDEALAKL-----------G-----INSS
NSPPSTM--SPSLAKSPPPAVASRPKPPFQSGTSNFIKEKQAPLRDLFSQTPPFPSTP--
-----PPPPALPPPLLRDPETHSAEPHVLTEPVGDQGISTQLLVPSGSVCFSYAGTPWKL
FLRKEVFYPRENFSHPYVLRLLCEQILRDTFTESCVRISQEERRRMKDLLGDLEVGLDSI
VSTKDSVKKRIVVAARDNWANYFSRIFPVSGDSGSDVQLLGVSHRGLRL---LKVTQGSG
------FQPD--PLKTLCSYNFAEVLGVECQGASTLELSLKNEQLVLHTPRAGTVKAMVE
LYLSE---LRKDS

PF00018 // ENSGT00920000148963_7_Domain_4 (2894, 2986)

DYVI-ALRSYITDDSSLLS-FHRGDLIKLLPMATLEP----------
------------------------GWQFGSSGGRSGLFPADLVQPAAAPDFLE--EQQGS
WRRSVPQRGEPGLAPGAEASEVRVTAEPSW------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MLL-

PF00063 // ENSGT00920000148963_7_Domain_0 (1175, 1532)

-AQEEEECRR------E---LLSWVP
VRQ------------------P-PRESCLDLLVDQPHSL-LSILDAQTWLSQ--------
---------------------------------------------------ATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVQHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VSSLFQE-----------AEP-QSRGGRGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
NPNPGKLPGLFDVGHVTKQLHQAAILEAVGTRSANFPVRVPFGAFLA-RFQALGSEGQED
LSDREKCGTILSQALGAESPLCHLGATKV--LLQEQGWQRLEELRNQQRSQALVNLHRGF
RTCISRQ--R--V--LPRMQARM-RGFQA-------------------------------
------RKRCLRRRAALGQLNTILLVAQPLLR--RRQRLQV-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------VMQFMGD---PRK

PF00784 // ENSGT00920000148963_7_Domain_5 (3143, 3255)

KDELDIPFEMLKLCWQ-NNLKDEIYCQLIKQVTENPKQ
EHCIRGWYLLNLLTGYFLPSPTLMPYVTKYLQNAA-----PSQELAQKCQEHLQHTAKYG
GRQHLPTIGEMKAFLEGNTIRSLLLHLSGGMEYKTVIQTFTVVAEVQKELCTQMGIREPL
EMQEFAIFLIKG----KGQLVRPLYLNEYLNDVVRE-TGVELHSHRLTWNTPLHYENEVY
ISMHYSQVHQDYLQGKLLVSTQHQVEALLAPLAALQHLSREIS-NLP-SEQDLLRYVPQP
LQ----QQVNLKILGNLVESQLRNLKRYNRKEAYINFIE---------------------
------------AVRLLPLFGYKVYGVLRVSEPTIVTPCLLGLNHQHLILVDPSS-----
---QEQFYSINLKDIQKLRHLSPLD--NTPGLELYYGSSANPKTIWFELPQAQELRHTLA
FLMEYST------STWPSLNL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MG
PLCQELGRLEIPAELAVMLKMAEGHQDALAGSITECLPPEVPARPSLTLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LVKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLAPGATRAHPPTQLEWM

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDTWQDLAGCDFQR
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------QRQARASEA--------A------SQASPSAITSK
PRKPP--------TPLEKPQH--DLESEGG----------CLRVR-SA-SSLGQGGW-AS
VVTLKAIWTLA---GQP----QITVRTMKPPAKVQIPQGEAQEEEEE-----EQ------
-EEQEVETRAVP-SPPPPPIMK-KPLKQGG------------AKAAKEAEAEPVKETAAK
DGGQG-----------PAQGR-GIVVRSSDPKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--PPITFLKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SSSPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGPLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAERRCLTQPMEDQGVSTQLLAPSGSVCFSYTGKPWKL
FLRKEVFYPRENLSHPYYLRLLCEQILRDTFSESCIRISQDERQKMKDLLGDLEVDLDSL
TTTEDGVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRVLAHDPGLEVGAGGK
------VTPA--HARPLR--SFAEVLGVECRGSSTLQLSLKSEQLVLHTARARAIEALVK
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3154)

PAAAPDFSFSKEQRSG
WHKGQLSNGELGLARWDRASERPAHPWSQAHSDDSEATSLPSSVSYASLSTDSHNYTMQE
FALLF-PRERAL-------PGQTDGGATGKDTDSLVQYTK----APIQESLLSLSDD-VN
KLAVASFLGDFRPQAHHSHPS----PHLPFLSP

PF00784 // ENSGT00920000148963_7_Domain_5 (3154, 3251)

QMCQE-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLNLLTGCFSPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRWMLPPGE

ENSGT00920000148963_7_Linker_5_6 (3251, 3354)

MKAFL--------------------------VAAEVQEELCQQMGITEPQ
EVQEFTLFLIKE----KGKLVRPLRPAEYLNSVAVD-QDVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3458)

HFDNSIY
ISTHYSQVLRDYLQGKLPVSAK--ADAQLARLAALQHLSKANG-NTP-SEQDLLAYVPQQ
LQ----RQVNMASIKNLMGQELRQLGGHSPQEAQISFIGGSG--A------------GTQ
SEFLPAPSPPAEAVSQLPLFGYTVYVALRVSMQALSGPALLGLNRQHLILMDPSS-----
---QNLYCRIALKSLQRLHLLSPLEEKGPPGLELNYGSADNPQTIWFELPQAQELLYTTV
FLIDSSA-SC---TEWPSVN-

MGGSKGKAPQRRALPGRPASAEQESGSASADG-APSHSRRPARGKAHRTRPAKEPDAT--
---SGGRRKPIEEESHRPGTSL-----ETQEREDSSQPRGHRSTGSREPRHSRGELPEEQ
RHLGEEEWMLKRGRRRK--GKERGPSALRGGGETPGRDGDTSGGDGGSSCLDSEHHEALD
S----GGASERPIKTEPSDKSTEGALIRRRES------MD-NNHQGNDGQALELSSREGP
LGTGSQGTSDDSRTDTDSSPGWPGHRCRPQKTP--GTSSRIPESQETELSREAAASSS--
-----LESSCAKNADTSDVEAQPKAELQDTEPETEE--PPRAQRLQVGEVTGKVQVVVSE
RDTGAREGAGAGDRRSRDPAPLAALVVLRKLRARAPTGESPQLAGGLHVGLKARLQRVAR
ALGFLRWLRLRLEQR----RGDERRASPREQ-----------------------------
----------------------------------------------------EERSRERA
LEARG-RAPGLPRWRAISLACRAV-LRRPSRAPPGGSLSPQQALTSSGSAG-ASVVEDAA
SDPKFAVVFPRVHSAEKESCSSTS-GA--STDAPTGE----------ECR--EEQGASEE
GVVRSGQAPSFAPSSPSGTPPDEN--QSEAEPETLEVETRVHWAQGTTPCVDPELGS-DS
LLPQLTLETRLR-HNSP--GRSPRERWEPEDDAEAALERDLELSLRKDLEMLHFPGAKAT
SLSEGLEDIEDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPLLLALNPHQPLPLFSPEV
STSYHPRKAPNTTPHIFAVGAAAYS-LSQSPGQDPCILLGGYSGSGKTEAAKRIVEFLSS
LGQKQTELGGAQLEDILPVLSSFGHAKTILNANASRFGQEFCLCLQQGVTVGASVFHYLL
ETSRVVFQAQAERSFHVFYELLAGLDAEDREKLSLQGPEAYYYLNQ-GRACRLQDKEDAQ
DFKGLLKALRVLGLCAEELTEVWAVLATILHLGNICFSSSERESQEVAAVSSWAEIHLAA
RLLQVPPECLEGAVT----KRVMDTPYGRVSRSLPVESAIDAR-DALAKTLY-SRLFSWL
LKQINVRLAPPREAAGVVTITVMDVYGFEALRV--NGLEQLCSNLASERLQLFSSQKLLA
QEEEECQREMLSWVPITQ---P-LRESCLDLLVGQPHSL-LNILDAQTWLSQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGDHPSYAKPQLPLPIFTVRHYAGTVTYQVSVLGHRFQGES---------VRPFES
PPSLFQE-----------A

PF00063 // ENSGT00920000148963_7_Domain_0 (1400, 1533)

EP-EGEREQSKPTLASRFQQSLGDLLARLGR-SHVYVIHCL
KPTPGKLPGIFDVGHVAEQLRQTGILEIIGTRSAHFPVRVPFRLFLA-RFRALGSGSQET
LSDQERCGTILSHVLGAESPVYHLGATQV--LLQEQGWHQLEQLWAQRRSQALLTLHRGL
RACITRQRLR--L--LPRIQARV-RGLQA-------------------------------
------RKRYLQRKSALGQLNAILLVARPLLQ--RRQKLQVR----GWERGPQSGEAWGK
RSRMDLGRLEIPAQLAALLRTAEGGT--QAGNITESLPPEVPVRPSLTLPPDIDQFPFSS
FVSSSFQKPYLPRPGQL-LDEPLTRMNGENPQQALEINRVMLRLLGDGSLQPWQEQTIG

PF00784 // ENSGT00920000148963_7_Domain_3 (1800, 1903)

T
FLIRKAQHQPGLRDELFSQLVAQLWHNPDEQQSQRGWALMAVLLSSFPPTPALQKPLLKF
VSDQAPRGMAALCQHKLLGALEQTPLVPMASRAHPPTQLEWK

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGLRRGRM--------AL
DVFTFNEGSYSAEVESWTTGEQLAGRILQSRGLEVPPRGWSVSLHSGDAWQDLAGCDFVL
DLIGQTEDFGD----PAGSRSYPITPFGLA-------------------ENIPPAPGVQA
PSLPPGLPPGPAPTL-PGS-SPPG---------------------EARK-PG-SLDGFL-
--DHIFEPVLSGGFSDLEQGWALSSRMKGGGSIGPTQ-QGYPM-VYPGMVQAPSYQPAM-
---MPAPMPMMPAMGTVPTIPAMMVPPQP------QPLLPSLDSRQLAVQQQNFINQQAM
ILAQQMTTQAMSLSLEQQNQRRQ-NGAQA----------------SAAASQTPPSVTAPK
PQKLT--------APQKTLES--RPEPLDV----------CFTEDTPE-ETEARPPRPKS
FQQKRDYFQKM---GQE----PIRVKTVKPPVKVQIPQEETEESE----E----------
--E---ETAEPT-PPPPPPVVK-KPLKQSK------------PKAVREDEAEPAKKEAPN
KDRM-------SNKDRPTQDR-EPTVHSSNSTP-QRPEPSREIRNIIRMYQSRP--GPVP
V-----------PVQPTR--PVKTFQKKNDPKDEALAKL-----------G-----INGA
HLPPLTT--SPNQSKGSPPVVAPRPKTRPRLEPSLSIREKQGPLRDLFGPHSPSPSITPA
PPPPPPPPPALPLSLPEEPKTRSVESRALMEPMEDRGISTQLLVPSGSVCFSYTNAPWKL
FLRKEVFYPRENFSHPYCLSLLCQQILRDTFAESCIRISQEERHKMKDLLGDLEVSLDSL
DTAEDTIKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTQDPS
------FHLE--RLKTLCSYSFAEVLAVECSGGSTLVLSLKNEQLMLHTAQARAIKAMVE
QFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FQRGDLIKLQPGVSPEP----------
------------------------GWQFGSVGGRSGLFPADMVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3155)

PAAAPDSSFSLGQRNS
WQRKSKPR--------QLKEPRPTHPGSQ---EPSEGSEATSYTAYSSLSADSHSYTMQE
FALRYFRKPHTS-------LTQAGRGAKKKAAANLIQYSK----DPIQESLISLSNEDMN
KRAVAGFKALMQFMGDQPKPRSTDELALLYELLK

PF00784 // ENSGT00920000148963_7_Domain_5 (3155, 3253)

LCQ--EDLRDEMYCQVIKQVTEHPEP
KHCALGWSILSLFTGFFAPSTTLMPYVTKFLQDSS-----PSQELARSSQENLQRTVKYG
GRQKLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQALRLLLIHLPGGVEYRTNIETFTVSGEVLQELCGQMGITDPQ
EVQEFALFLIKG----EGELVRPLSPHEYINSVMTD-QDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPTY
TEIHYGQVLRDYLQGKLMISAQ--EDAQLARLAALQHLRKASK-SPPSEQ-ELLAYIPKP
LQ----WQVNTASIKSLVSQELKQMQGCSSLRAQTDFIE---------------------
------------TTAQLPLFGYTVYMVLRVSKLVLPGPVLLGLNRHHLVLMDPSS-----
---QKPCCSIPLKDLQRLHLLSPLQDDGVPGLELNYGSADNPKTIWLELPQAQELKHTIV
FLMEEGSMSST---QWPGLG-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------NSEATSLPSSMVYTSLSTDSHNYTMQE
FALRYFRKPLAL-------LDLTVGGAKAKDMAILVQYSKVRGQTPIQESLIRLSDD-TS
RQAVAGFETLMQFMGDQSKPRGKDEMDLL

PF00784 // ENSGT00920000148963_7_Domain_5 (3150, 3253)

YELLKLCRE-EDLRDEMYCQVIKQVTGHPKL
EYCARGWNLLSLFTGFFPPSTTLMPYVTKFLQDSG-----PSQELARRSQQHLQRTVKYG
GRQQLPRPGEMR

ENSGT00920000148963_7_Linker_5_6 (3253, 3353)

AFLKGQAVRLLVIHLPGGVDYKTNVQTFTVAAEILEEMCGQMGITDPQ
EVQEFALFL-DK----EGELVRPLWPHEYLNSVIVN-LNMSLHNRRLIWETP

PF00373 // ENSGT00920000148963_7_Domain_6 (3353, 3505)

LHFDHPVY
IGTLYGQVLQDYLQGKLMGHAQ--ADGQLAHLAALQHLGRASK-SPP-SEQDLLGYIPKT
LQ----WQVNMDSIKNLMDQKLRQLQGQSSQDAQISFIE---------------------
------------ATRQLPLFGYTVYVVLRVSKLVLPGPALLGLNRQHLVLMDPIS-----
---QKMCSSIALKDLQRLHLLSPLEPSGLPGLELNYGSADSPQTMWLELPQAQELYHTVL
FLLD-GSASSIQP-QGPSLS-

MGGSKGKASQRQEGLRRPVSGEQESRSGSAHC-SPSQEGGQGRGKARRTRPVLEPVTAGS
HRTHAGRRKPTAEQKGGCRRSGAQGRLGSARRRGRGSKESREPREDR------GRRLEEE
SLSREGTTS--ELCRRRRRGKGRGPSARQGCRETRSLHGDTSGGDGGSSCPDSEAREAQE
SDSQSTGAPELRPKPEQKDTVPGDTQTESEPE-LE---PGERPSSDGGGSAEPRS-REGS
SGVGPQGEKEDSGTVTESSLEGAGPGGGPRTAP--GTASQAPSPLEG--------SPECV
PRSSRASRDPRLARDTRNSEARPEAESQGAEPGR--AEASGTRRLQVGKAVGEVQVAAGE
SESGAGAGD-----GPRDPAPLAAVXXXXX------------------------------
------------------------------------------------------------
--------------------------------------------------------XXXX
XXXXX-XXPGPRRRLALRLA-GVARLGARPRPPPGGGSSSPQPSKSPAPEG-PSEDEDRS
PDPKFAVVFPRMHRTGRESSSRSSEEA--SADAPA-----------RGDA--EGRRASGE
SVAGPRRGSLLGPAPRDEPPLDESGSSSEAGPETLEAEAPVHWTQSSEPREDPGLDADDA
LLPRLTLETHLRWERSPGPCGPPRGRWVPEDEAEEALERDLELSLGPGLEVPPSLGAEGR
SLAEGLED

PF00063 // ENSGT00920000148963_7_Domain_0 (789, 1534)

TDDLARLRPVCNSSVLLCLKKRFHLGRIYTFGGPFLLSLNPRRPLPLFSAEV
LASYHPKKALNTTPHIFAIVASAYR-LSQSTGQGTCILLGGHSGSGKTEAAKKIVQFLSS
LEQEQTRDRRCQLDGVLLMLRSFGHAKTVLNANASRFGQVLRLCLQRGVIVGASVSHYLL
EASRVVFQAQAERSFHVFYELLAGLDPVAREQLSLQGPETYYYLNQ-GQACRLQGKDDAQ
DFEGLLKALQVLVTRPEELTAAWAMLAAILQLGNVCFSSSERESQEVAAVSSWAEIHTAA
RLLLVPPERLEGAVT----RKVTETAYGWVS-----------G-DALAKALY-SRLFTWL
LGRTNAQLAPPGEGESMDTVTVVDVYGFEALRV--NGLEQLCNNLASERLQLFTRQTLLA
QEEEACQRELLPWVPVPQ---P-VRETCLDLLVDQPHSL-LSILDAQTWLSQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGSHPCYAKPQLPLPIFTVRHYAGTVTYQVHKFVDRNRDHLDPAVVEMLAQSQLQL
VGSLFQE-----------AES-RSGDGRGKPTLASRFQHSLEDLLAQLGR-SHVYFIQCL
NPNPGKLPGLFDVEHVAEQLLQAGILEAVCTRSANFPVRVPFQAFLARA----PGWGRPK
SSDRERCGAILSQVLGAESPLCHLGATQV--LLRESGWRQLEWHWARRRSQALLALHRSL
RACVSRQRLRLLL--LPRMQARV-RGLQA-------------------------------
------RSRYLRRRAALGQLNTILLVARPLLW--RCTLS-------------------IA
PLCQELGRLEIPAELAVMLKAAEGRQHVLADSITESMPPEVPVRPKLTLPPDIDQFPFSS
FISISFQEPSLPHPGQP-LTKPLTQLVGENTQHALDINKVLLRLLGDGSLPSWQEQT

PF00784 // ENSGT00920000148963_7_Domain_3 (1798, 1903)

MGE
YLVRQGQRRPGLRDEIFSQLVAQIWHNPDEQQSQRGWALMAMLLSAFPPMPTLQKPLLKF
VSDQAPTGVAALCQHKLLGALEQTRLAPGMARAHPPTQLEWT

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGRRRGRM--------AL
DVFTFNEECYSAEVESWTTGEQFAGSILQSRGLEVPPRGWSVSLHSRDSWQDLAGCDFVL
DLIGQTEDLGD----PVSPRSYPIAPRGLP-------------------EDIPPAPGIQA
PSLPPDPPPGPPPTL-SSR-SHTG-----------------------------SLDGFL-
--DHLFEPVLSPGRSDLEQGWALSSRMKGGGAIGPMQQGSYPM-VYPGMMQMPGYQPAM-
---MPAAMPMMPAVGAVPAMPAMVVPQQPQ----PQPLLPGVDPRQLAAQQQNFINQQAL
ILAQQMTTQAMTLSLEQQTHQRQ-RQAEVQTRGA--------A------APTSPPAVTPK
PKKPL--------VPREEPEQ--ELESVGA----------RLREADGQ-AR---------
WRVIGPSGALS---GQQ----QIKVKTVKPLAKIQIPQEEEQDEEQDEEEPRAG------
-GG---EHG---------GWAG-PALWVWG------------AKAAREAEAEPAQEAGPG
-ADPE-----------PAQDR--DLVRSSDPAPRRRAEPSREIRNIIRMYQMQP--SRWV
PGVTRAAHSPGSHPVDSR--PPTSFMKKNNPKDEALAKL-----------G-----ISGA
HTSTS-----VSPKKGPPPPVAPRPKVPTQLGPSNSIKEDQG----LFGQTPPTAHAP--
-----PPPPAPP--LPGEPGTLSAEPRGLMEPMGDQGVSTQLLVPSGSVCFSYVGAPWRL
FLRKEVFYPRENFSHPYCLRLLCEQILRDTFAESCIRISQDERHKMRELLGDLEVGLDSL
STTEDNVKKRIVVAARDNWANYFSRIFPAERRAGDGTCHLPSGQGESSNDVLLKVTQGPS
------VHLN--QLKTLCSYSFAEVLGVECLGGSTLELSLKAEQLVLHTARADAIKATIE
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FHRGDLIKLLPVAALE-----------
-----------------------PGWQFGSTGGRSGLFPANMVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3150)

PAAAPDFSFSPE-RSG
RHMSQLQHGEPGLR--------HAHPRSRTHSDNSEATSSTHSAAYLSLSTESHNYTMQE
FALNHFRKPQTL-------PP------------TQSLWPQ----APIQESLISLSDEDAN
RQAVESFQVLMQFMQDQPKPRGKNESELL

PF00784 // ENSGT00920000148963_7_Domain_5 (3150, 3253)

YELLRLCRE-ENLRDEIYCQVIKQVTGHPQQ
EHCARGWSFLSLLAGFFPPSTTLMPYVTKFLQDSG-----PSQELAQKSQEHLQHTVKYG
GRRRLPSPAEIQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3355)

AFLKGQAVRPLLIHLPGGLDYKTSIQTFTVAAEVLEELCRQIGITDPQ
EMQEFALFLIKK----EGELVRPLWPHEYLNSV-LD-QDVSLHSRRLSWETQLH

PF00373 // ENSGT00920000148963_7_Domain_6 (3355, 3505)

FDHPTY
VTTHYKQVLRDYLQGKLLVSPQ--ANAQLARLAALQHRSQTQE-DRL-SEQDLLAYLPKP
LQ----RLVSTSTIKNLMEQELKWMQACSSQEAQISFIE---------------------
------------AVSQLPLFGYTVYVVLRVSQLALPGPSLLGLNRQHLILMDPSSQLCCL
YCPQKLYCSVALKDLQRLHLLSPLESNGPPGLELNYGSADNPRTIWFELVKVSGQGLR--
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MSSVWYGDTNWFAVSMEPCVSYPP
SNRPSTEESYSAEVESWTTGEQFAGWILQSRGLEAPPRGWSVSLHSGDAWRDLPGCDFVL
DLIGQTEDLGD----LAGPHNYPIATLGLA-------------------ESIPPAPGVQA
PSLPPGLPPGPAPTL-ASS-RPPG---------------------EASR-RG-NLDGFL-
--DHLFEPALAPGFSDLEQGWALSRRMKGGGSIGPTQ-QGYPI-VYPGMVQAPTYQPAM-
---IPAPMPVMPAMGTVPTMPAMMVPPQP------QPLVPSLDSRQLAVQQQNFINQQAM
ILAQQMTTQAMSLSLEQQNQRRQ-HQAQA----------------SGATSQPPPSTMAPK
AKKPP--------APQEKPES--DLEPSGV----------CLREDTPE-ETESRPQRPKS
FQQKRDYFQKM---GQE----PIKVKTVKPPAKVQIPQEETEET--------EE------
-EE---TAELSP-PPLPPPVMK-KPQKPSR------------PKAVKKDEMEPAQEEVPT
PGGDPPVHSSKSAPQPPKPSR-APPVQSSNSAP-QRPQPSREIRNIIRMYQSRP--GPVP
V-----------PVQPTR--PIKTFQKKNDPKDEALAKL-----------G-----INGV
PLPL-ST--SPNQGKSSPPAVVPRPKARPRLEPSLSIQEKQGPLRDLFGPCSPNPPTAPA
PPPP----PALPPPMSGEPKTPSVEPPALTEPMEDKNISTKLLVPSGSVCFSYANASWKL
FLRKEVFYPRENFSHPYCLNLLCQQILRDTFTESCTRISQDERHKMKGLLGDLEVGLESL
DIVEDSIKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTQSPS
------FHLD--QLKTLCSYSYAEVLTVQCKGRSTLELSLKNEQLILHTVWARAIKAMVE
QFLSE---LRKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDNSLLS-FHRGDLIRLLPVAALEP----------
------------------------GWQFGSAGGRSGLFPDDVVQPAAAPDLSFSLGKRNS
WQRRSKPG--------P-AQEVRED-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MSS
------------------PCVATSPDDSSPAQLPPRGTSSSCCRWPLWNP----------
------------------------GWQFGSTKGRSGLFPADLVQPAAAPDFSFSEQGSSR
WRKSQLPLGEPGLAQWSRVSERPAHRRSQAFSDDSEATSLPSSVAYSSLSADPHNYTMQE
FALRYFRKPQTP-------LDLTG---EGKARASLVQYTK----VPIQESLISFKDEDTS
RQAVASFQALMQFMGDQSKRRGKDAVNLLYELLKLSGE

PF00784 // ENSGT00920000148963_7_Domain_5 (3159, 3254)

-ENLRDEIYCQAIKQVTGHPRP
ERCARGWSFLSLLTGFFPPSTTLMPYVTKFLQDSG-----PGQELARSSQKNLQRTVKYG
GRRRLPPPSEMKA

ENSGT00920000148963_7_Linker_5_6 (3254, 3354)

FLKGQVARLLLIHLPGNVDYKTNIETFTVAAEVLEELCGQMGISDPQ
ELQEFALFLIKG----EGELVRPLWPHEYLNSVLVH-QKVSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDNSTY
ISTHFSQVLRDYLQGKLMVSAQ--ADAQLARLAAFQHLGKADK-NP-PSEQELLTYIPKL
LH----WQVDVAAVRSLMGQELQKLQGHSSQEAQISFI----------------------
-----------KATSQLPLFGHTVYVVQRVSNLALPGPALLGLNRQHLLLLDPGS-----
---QKTCGSIDLKDLQQLHLLSPLEPGGPPGLEINYGSADSPQSMWLELPQAQELLYTIV
FLLDSSL-PV---AQWPGLH-

MGGSKGKAPQRRAQPRRPASAEQESGSASADG-APSRDRRLARGKAHKARPAKEPDATED
EGTSGGRRKSTEET-------R-----E--RQGSSQRPRGRRPTESREPGDSRGELREEQ
RLPKRG------RRR-R--GKERGPSA-------PGRDADTSGGDGGSSCLDSEHHEALD
SSSQGGGASERPTKTEPGDTGSEGALIRSPGA------TG-SSHQDNGGHALGLRSGEGP
SGSGPRGAGDDSRTDADSSSGWAGHGRRPRKTP--GASSSIPESQETELGGEAVASGS--
----LGSSS-IADVSDSDVGAQPKAELLGTEPETAE--APRAQRLQVGEAAGKVQVV--K
SDAGARGGAGAG-----DPAPLAALLVLRKLRARAPAGASPQPAGGLRVGLKARLQRVAQ
ALGLLRWLRLRVQQH----RGDARGESPREH-----------------------------
----------------------------------------------------KERGRERA
LEARG-GLRGPPRWRAVRLACRAV-LRAPPRAPPGGSPSLPQALKSPSSEG-ASAIEDAA
PDPKFAVVFPRIHSAEKESGGGSS-GA--STDAPTGEGA-------AEYR--EEQGAREE
GVVRSHQPPSFSPSAPDGTPPDEN--RSEAEPDTLEVESRVHWAQGSTPCADPGVGT-GT
LLPQLTLETRLQ-QNSP--CRSPREQWEPEDDAEAALERALELS----LEMPPFPGAKTR
SLPEALED

PF00063 // ENSGT00920000148963_7_Domain_0 (789, 1533)

TEDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPLLLALNPHQPLPLFSPEI
LASYHPRKAANTTPHIFAVGAAAYR-LSQSAGPAPCILLGGHSGSGKTEAAKKIVEFLSS
LGQKQAEARGAQLEDILPVLSSFGHAKTILNANGSRFGQELCLCLHHGVNVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDPGDRELLSLQGPEAYYYLNQ-GQTCRLQGKEDAQ
DFKGLVKALQVLGLCAEELSEVWAVLATILHLGNICFSSSERESQEVAALSSWAEIHLAA
RLLRVPPERLEGAIT----KRVLDTPYGRVSRSLPVESAIDAR-DALAKTLY-TRLFNWL
LKQINVLLAPPREADSVATITVVDAFGFEALRV--NGLEQLCSNLASERLQLFSSQRLLA
QEEEECQREMLSWVPIPQ---P-RRESCLDLLAGQPHSL-LSILDSQTWLAQ--------
---------------------------------------------------ATDHTFLHK
CHYHHGDHPSYAKPQLPLPIFTVQHYAGTVTYQVHKFINRNRDHLDSAMVEMLGQSQLQL
VCSLFQE-----------AEP-QAGREEGKPTLASRFQQSLGGLLARLGR-SHIYVIHCL
NPTPGKLPGLFNVGHMAEQLLQAGILEVIGTRSAHFPVRVPFQLFLT-RFRALGSGRQEA
LSDQERCGAILSQVLGAESPVYHLGNTQV--LLQEQGWQQLEQLLGQQRSQALLTLHRGL
RACITRQRLR--L--LPRMQARV-RGLQA-------------------------------
------RKRYLQRKSALGQLNTILLVARPLLQ--RRQRRQV-----M-------------
-GGGDLGRLEIPAQLAALLETAEGHQAILAGSITESLPPGVPVRPNLTLPPDIDQFPFSS
FVSSSFRKPYLPRPGQL-LDEPLTRMDGENPQQALEINRVMLRLLGEGSLQSWQEQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLIRKAQHRPGLRDELFSQLVAQLWHNPDEQQSQRGWALMAALLSSFPPTPALQKPLLKF
VSDQGSRGMAALCQHKLLGALEQTQLAPMASRTHPPTQLEWK

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGLRQGRM--------VL
DVFTFNEESYFAEVESWTTGEQLAGRILHSRGLEAPPRGWSVSLHSGDAWQDLAGCDFVL
DLIGRTEDLGD----PAGSHNYPITPLGLA-------------------ENIPPAPGVQA
PSLPPGFPPGPAPTL-PSS-GPPG---------------------EARK-PG-NMDGFL-
--DYIFEPVLSSGFSDLEHSRALSSRMKGGGSIGPTQ-PGYPM-GEASQAPQQGWSES--
-----------PQATEMGALATMMVPPQP------QPLLPSLDSRQLAVQQQNFINQQAM
ILAQQMTTQAMSMSLEQQNQRRQ-NQAQA----------------SGAPSQTPPPA----
PKKPP--------ASQEKPES--DPEPL--------------DGDTPE-EATGRPQRPRS
FQQKRDYFQKM---GQE----PIRVKTVKPPAKVQIPQEETDENEDEEEE----------
--E---DTAESS-PPPPPPVVK-KPLKQTK------------PNSAKDG-AEPAEEEKPT
PGRAPKVK--SSTPQSPPPSR-APTVSSSNSTP-QRPQPSREIRNIIRMYQSRP--GPVP
V-----------PVQPSR--PVKPFQKKNDPKDEALAKL-----------G-----ISGT
HLPPSAM--SPNLGKNSPPAVAPRPKARPQLEPSLSIQEKQGPLRDLFGPCSPNPSTTPA
PPSP----PPLPLSLPEEPKAHSVGSHALTEPMEDLGISTKLLVPSGSVCFSYASAPWKL
FLRKEVFYPRENFSHPYCLNLLCQQIIQDTFTESCIRISQSERQKMKDLLGDLEVGLDSL
DSTEDSIKKRIVVAARDNWANYFSRIFPVSGESGSDIQMLGVSHRGLRL---LKVTRDPS
------FHLD--RLKTLCSYSFAEVLAVGCSSSSTLELSLKNEQLTLHTAQARAIKAMVE
QFLNE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FHRGDLIKLLPAGILEPDWQGRRT---
------------IIWE-----CLLGWQFGSVGGHSGLFPADVVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3154)

PAAAPDFSFSLGQRNS
WHRKSKTG--------P-AHERPTHPRSQ---EPSEDSEATSFAAYSLFSADSHNYTMQE
FALRYFRKPQTL-------LAQAGRGANDKAEVSLVQYTK----DPIQESLLSLSNEDIN
RKAVAGFKALMQFMGDQPKPRGKDELDLLYELL

PF00784 // ENSGT00920000148963_7_Domain_5 (3154, 3253)

TLCR--EDLRDEMYCQVIKQVTGHPQP
NHCVLGWNVLSLFTGFFAPSTTLMPYVTKFLQDSS-----PSQELARSSQENLQRTVKYG
GRHKLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRSLLIHLPGGVDYRTNVQTFTVAGEVLEELCGQMGITDSQ
EVQEFALFLIKG----EGELVRPLSPHEYLNSAVTD-KDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPTY
TETHYGQVLRDYLQGKLMISAQ--ADAQLARLAALQHLRKASK-SLPSAQPLLLVYIPKP
LQ----QQVNIANIRSLVGQELRQMQGYSAQRAQIDFIE---------------------
------------STTQLPLFGYTVYVVLRVSKLSLPGPILLGLNRQHLVLMDSSS-----
---QRLCCSIPLRDLQRLHLLSPLEDNGAPGLELNYGSADNPHTIWLELPQAQELKHTIV
FLLE-DSMSST---QWPGLS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------DSEATSYSAYSLFSADSHNYTMQE
FALHYFRKPQTL-------PAHAGRGAKEKAEVNLVQYTKVRGQDPIQESLLSLSNEDMS
RKAVAGFKALMQFMGDHPKPRGKDDLELLYELLA

PF00784 // ENSGT00920000148963_7_Domain_5 (3155, 3253)

LCR--EDLRDEMYCQVIKQVTGHPQP
KHCALGWNVLSLFTGFFAPSTTLMPYVTKFLQDSS-----PSQELARSSQENLQRTVKYG
GRQKLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRLLLIHLPGGVDYRTNVQTFTVAGEVLGELCGQMGITDSQ
EVQEFALFLIKG----EGELVRPLSPHEYLNSVVTD-KDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPTY
VETHYGQVLRDYLQGKLMIGAQ--EDAHLARLAALQHLRKASK-SPPSEQE-LLVYIPKP
LQ----EQVNIASIKSLMGQELRQMQGYSPQRAQIDFIE---------------------
------------STAQLPLFGYTVYVVLRVSKLMLPGPVLLGLNRQHLVLMDPSS-----
---QRLCCSIPLKDLQRLHLLSPLEEGGLPGLELNYGSAENPQTIWLELPQAQELKHTIV
FLLE-DSMTST---QWPVLS-

MGRKKGKAPPRHAKAGTPASGEQESGSASADG-EPSREHRPGRDKARGVGQDTEPAAAGG
QGTAGGRMKPTADRDSPSRRPRAERPAEAQEGEGS-TRQGRGSKESREPGDRCGGRLEQG
SLPQEEGRTGERGRR-RKRGKERGPSARRGHHATKSLDGDTSGGDGGSSCPDSEAREVQE
SSGQNGGAPELRPKPEPTDTGSEWTDAGPDSAPEPCE------LLSTDG-----------
-----------LSSDEPCDLRGPGPGRAPGTPSRPGGRATAP----------------RP
SESTRAPRDTAPAWDAGDIGAQ-----RAVGPGTAEASTARALRRRVGKVVGKVQVEAGE
R-------AAAGEDVPGDPAPTAALVVARRLRAMPPPGPTPQAAGPRRASLKERLLRVVR
ALGLLRWLRLRLGPR----DPDGRGAGPRAD-----------------------------
------------------------------------------------------------
-AGRG-RGPGLRRRLALRLA-GVAGLGGHPKALPGGGSSPPQVPKSPVSDD-PSDQEDPS
PDLKFAVVFPRIHRAGRASSSRSSGEA--SADAPAGEGRVWPRAGAGGDG--EGRGASGE
GEAGPRRASILAPTAPDGPPLDESRSGSEAEPEPLAAETPGHWAQGSGPREDPGLGT-AA
LLPQLALETRLQQERTPGPGGALGERWEPEDEAEAALERDLELSLGPGLEALPLL-----
----GLEDTEDLA-----------------------------------------------
-----------RLR

PF00063 // ENSGT00920000148963_7_Domain_0 (855, 1202)

HIFAVVASAYS-LSQSTGQDPCILLGGHSGSGKTEAAKRIVQFLSS
LEQEQTRDRGCQLDDVLRILSSFGHAKTVLNANASRFGQVVCLCLQHGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLEPMEREQLSLQGPETYYYLNQ-GQACRLQGKEDAQ
DFTELTKALQVLGLCPEELTTVWAVLATILQLGNICFSSSEHESQEVAAVSSWAEIHAAA
RLLQVPPERLERAVT----RRIVETPYGQVSRSLPVESAIDAR-DALAKALY-SRLFSWL
LTRINARLAPPGEGGSVGTVTVVDAFGFEALRV--NGLEQLCNNLASERLQLFCGRVLLA
QEE-------------------PPRVSCLDLLADQPHSL-LSILDAQTELSQVRVSL---
---------CFPGWR--A--AARGKHICP--SY-----------------QATDHTFLQK
CHYHHGEHPSYAKPQLPLPIFTVRHYAGTVTYQVHKFLNTNRDHLDPAVVETLGQSQLQL
VGALFQE-----------AGP-EARGGRGRPTLAARFQQALGDLVARLGR-SRIYVIQCL
SPNPGKLPGCFDVGHVAEQLHQAGVLEATGARSANFPVRVPFGAFLA-RFRALGTAGPED
PSDRERCGTILSQALGAESLFYHLGATKV--LLQEQGWQRLEQLRAQRCSQALLTLHRGL
YSCISRQRRR--L--LPRMQARV-RGLQARSAGAAAMAAEGGSVFSHPCSIWTLHPCPSP
PPPMASRKRYLRRRAALGQLNTVLLLARPLLW-RRQ-KLQLG----HWCGWRGDG-ASGT
APSMELGSLEIPAELAVMLKTAEGHQDSLAGSITESMPPEVPARPSLSLPPDIDRFPFSS
FVSIGFQEPSLPRPGQP-LAKPLTRLDGENPQHALDINKVILRLLGDGSLQTWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQRRPGLRDELFSQLVAQLWQNPDEQQSQCGWALMAILLSAFPPMPALQKPLLKF
VSDQAPRGTAALCQHKLLGALEQSQLAPGTARAHPPTQLEWMAGWRRGRM--------TL
DVFTFNEECYSAEVESWTTGEQLAGWILQSK--------------YGDAWQDLAGCDFVL
DLIGETEDLGD----PASPRSYPITPLGS-------------------AEAIPPAPGVQA
PALPPGLPPGPAPVL-PRR-GHTG---------------------KAGVGIL-SLDGFL-
--EHIFEPVFSPGFSDLEQGRALSGRMKGGGAMGPMQQ-GYPM-VYPGMMQMPGYQPP--
-M-VPAPVPMMPGMGAVPAMPPMMVQPQPQ----PQPLLPSLDTRQLAVQQQNFINQQAL
ILAQQMTTQAMTLSLE-QQTRQRQR----Q------------AQALEAASQAPPSAITPK
PKKPP--------APREEPEP--ELESVGA----------CLR-GSSE-EPEDRPQQPKN
FQEKREYFQNM---GEGSPQPGLGVKTVKPPAKVQIPQEEEQEEDIR--GWGL---G---
-----LGAAVLLLSPPPPPIVK-KPLKQSG------------AKAAKEAEVQPAEEAGPG
-RDR-----------GPARDR-GPVVRSSDPTS-QRPEPSREIRNIIRMYQSRP--GPVP
V-----------PVQPS--RPFRTFPKKNDPKDEALAKL-----------G-----IQGA
HLSPEMP--SP---KGPPPAVAPRPKALSQPGPSSSIKEKQEPLRDLFGQNPPTAQAP--
-----QPPPAPPLPLPEDPGAPSAEPRGLPEPMGDQGPSTQLLAPAGSVCFSYASAPWKL
FLRKEVFYPRENFSHPYCLQLLCEQILRDTFAESCIRISQDERRKMKDLLGDLEVGLDSL
ATAEDSVKKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKSLGWGM
------VGGKRALAHAPLVHSFSEVLGVECPLGSTLELSLKNEQLVLHTARARSIKAMVE
LFLSE---LKKASAGWWGARRAASTRAVSPLS-VLSGS-----APLGYLP----------
------------------------GWQFGSAGGRSGLFPADIVQPAAAPDFSFSLEQRSS
QRKRHSQLREPGLAQWDRASEHPTRPRNQANNDDSEATSLPSSTAYASLSSDSHSYTMLE
FALRYFRKPRTL-------LDPTDGGAQGKAMVSLVQFSK----APIQESLLSISDEDMS
RQAVVSFQALMQFMGDQSRPRGKDELDL

PF00784 // ENSGT00920000148963_7_Domain_5 (3149, 3253)

LYELLRLCQE-ECLRDEIYCQVIKQVTGHPRQ
DHCARGWSFLSLLTGFFRPSTTLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRQRLPLPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AF--------------------------LVAAEVLEEMCRQMGITEPQ
EVQEFALFLIKG----EGKLVRPLRLGEYLNNVVME-RDVSLHGRRLTWKTPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3458)

HFDNPTY
VSTHYSQVQRDYLQGKLRVSAQ--ADVQIARLAALQHLGRDKK-NP-PSEQDLLAYVPKL
LQ----WEVNVNTIKNLMGQELRQLQGYSPQEAQISFIGGQARQVLE----------LWQ
SEPLPWPSPLPEAMSQLPLFGYTIYVVLRVSKLHLPGPTLLGLNHQHLLLMDPSS-----
---QKLRCSIGLKNVQRLRLLSPQEEGGPPGLEINYGSPDSPQTTWFELPQAQELLYTIV
FLLDSTC-S----LEWPGLN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------DSEATSFTAYSSLSTDSHNYTMQE
FALRYFRKSLLL-------LDQTG-GSAKKAAVNLVQYSKVRSQAPIQESLIDLRNDDMS
KQAVAGFQVLMQFMGDQSKPRSKDELVLLYELL

PF00784 // ENSGT00920000148963_7_Domain_5 (3154, 3253)

KLCRE-EDLRDEMYCQVIKQVTGHPHP
EHCALGWSILSLFTGFFAPSTTLMPYVTKFLQDSS-----PNQELAQNSQENLQRTVKYG
GRQQLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKKQAVRLFLIHLPGAVDYRTNIYTFTVAGEVLEELCGQMGITDPQ
EVQEFALFLIKG----EGELVRPLSSHEYLNNVVTD-KDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPTY
IETHYSQVLRDYLHGKLMASAQ--ADAQLAQLAALQHLSKASK-SPP-SEQELLAYIPKP
LQ----WQVNMANIKNLVDQELRQLQGHSSQTAQISFIK---------------------
------------ATSQLPLFGYTVYMVLRVSKIVLPGPILLGLNHQHLVLMDSSS-----
---QKLCCSITLKDLQRVQLLSPLEENGPPGLELNYGSADKPQTIWMELPQAQELQYTII
FLLN-SSMTST---QWPGLN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MVE
LFLSELK---KDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FQRGDLIKLLPVATLEP----------
------------------------GWQFGSTGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3145)

PAAAPDSFFSTEQRSS
QGHKGQ----LQRREWDRASEFPTHAWSQARSDNSA-TSLSPSVAYVALPT-DSDYTMQE
FALRYFRKPQTL-------PAQTGGDAE-KATASLVQYSK----APIQESLISFSDEDTN
RQAVESFQALMQFMGDQSKPRGKN

PF00784 // ENSGT00920000148963_7_Domain_5 (3145, 3254)

ELDLLYGLLKLCQEKEDLRDEVYCQAIKQVTGHPRP
KLCARGWRFLSLLTGCVPPSNTLMPYVTKFLQDWG-----PHQELAQSSQEHLQRTVKYG
GRRRLPSPGEMQA

ENSGT00920000148963_7_Linker_5_6 (3254, 3356)

FLKGQVVHLVLIHLPGGVDYKTNIRTFTVAAEVLEELCRQMGITDPQ
EVQEFALFLIKG----DGELVRPLWPQEYLNSVLGG-LDVSLHSRRLGWETRLHF

PF00373 // ENSGT00920000148963_7_Domain_6 (3356, 3505)

DNPTY
ISTHYGQVLRDYLQGKLGLSPQ--EDARLARLAALQQLSRSTE-EPP-SEQDLLAYVPRQ
QQWQQQWQMNVATVKSLMGRELRQLQGCSPQEAQISFIK---------------------
------------AVSELPLFGYTVYLVLRVSNPALPSPGLLGLNRQHLVLMDPGS-----
---QELCCSIALRDLQRLHLLSPLEAEGSPGLELNYGSADNPQTIWFELPQAQELKHTIT
FLLDGNP-----PSS------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------PVCCARARLDPVG-----------YTA
SALGITHPCALARMKEASGVGGGHSPMCP--RHCHMPPGPAGEWPGATVQQPRQRAPTAL
L---QPDAAGPGGGGVSAGVAVLGA----------------CPSASEG--------V-L-
-PR-------------------PPGRSA-----------------PQPPEYPGR------
-----------------------PDMAVPGWSA-----MVWSRLTA

PF00063 // ENSGT00920000148963_7_Domain_0 (1307, 1529)

TSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQL
VGSLFQE-----------AEP-QSRGGRGRPTLASRFQQALEDLIARLGR-SHVYFIQCL
TPNPGKLPGLFDVGHVTEQLHQAAILEAVVTRSANFPVRVPFEAFLA-RFRALGSEGQED
LSDREKCGAVLSQVLGAESPLCHLGATKV--LLLEKGWQRLEELRDQQRSQALVNLHRSF
HTHISRQR----I--LPRMQAR-VRGF---------------------------------
----QARKRYLRRRAALGQLNTILLVAQPLLR--RRQRLQLG----HWQGWHSSERALER
VPSMELWRLEIPAELAVMLKTAEGHQDALAGSITECLPPEVPARPSLTLPADIDLFPFSS
FVAIGFQEPSLPRPGQP-LAKPLTQLDGENPQHALDINKVMLRLLGDGSLESWQ

PF00784 // ENSGT00920000148963_7_Domain_3 (1795, 1900)

RQTMGT
YLVRQGQCRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLWALEQSQLASGATRAHPPTQL

ENSGT00920000148963_7_Linker_3_4 (1900, 2895)

EWLAGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQSRGLEVPPRGWSVSLHSRDAWQDLAGCDFVL
DLISQTEDLGD----PARPRSYPITPLGSA-------------------EAIPLAPGIQA
PSLPPGPPPGPASTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVISSGLSDLEQSWALSSRMKGGGAIGPTQQ-GYPM-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP-----PQPLLPSLDAGQLAVQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQR--QRQ---------------ARASEAASQASPSAVTSK
PRKPP--------TPPEKPQR--DLEAEGG----------RLR-EISE-EAEDRPYRPKS
FQQKRNYFQKM---GQP----QITVRTMKPPAKVHIPQGEVQEEEEEEQE--------E-
QEEQEVETRAVP-SPPPPPIVK-KPLKPGG------------AKAPKEAEAEPAKET-VA
KGRG----------QGPAQGR-GIVVHSSDSKP-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQP--SRPPKAFLKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SPSPGKGPPPAVAPRPKAPLQLGPSRSIKEKQGPLLDLFGQKLPTAQTPP-
---PPPAPP---LPLPEDPGTLSAERRRLTQPMEDQGVSTQLLAPSGSVCFSYTGTPWKL
FLRKEVFYPRENFSHPYYLRLLCEQILRDTFSESCIRISQDERRKMKDLLGGLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGESGSDVQLLAVSHRGLRL---LKVTQGPG
------LRPD--QLKILCSYSFAEVLGVECRGSSTLELSLKSEQLVLHTARARAIEALVE
LFLNE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLEP----------
------------------------GWQFGSAGGRSGLFPADIVQPAAAPDFSFSKEQRSG
WHKGQLPNGERGLARWDRASEVRKMGEGQPEARPA-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------DSEATSLPSVTAYTSVSSDSHSYTMQE
FALRYFRKPLTL-------STAN----------------PLWPQAPIQESLISLK-EDAS
RQAVAGFRVLMQFMGDQSKSWRKDELDLL

PF00784 // ENSGT00920000148963_7_Domain_5 (3150, 3253)

YELLKLCQE-EELRDEMYCQVIKQVTGHPRP
ERCARGWSLLSLFTGFFPPSTTLMPYVTKFLQDSS-----PSQELARSSQEHLQRTVKYG
GRQQLPSPAEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

ALLKGQAVRLLLIHMPGAMEYRTNIQTFTVVGEVLEELCGQMGITDPQ
EVQEFALFLIKG----EGDLVRPLWPHEYLNSIMVD-QDLSLHTRRLGWESPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFEHPTY
VSIHYSQVLRDYLQGKLMASAQ--ADAQLAQLAALQHLSKASP-SPP-SEQDLLAYIPKP
LQ----WQVDMATIKTLVGQELRQLQEYSPQKAQISFIE---------------------
------------ATRQLPLFGYTVYVVLRASKLVLPGPVFLGLNRWHLVLMDPSS-----
---QKLCCSITLKDLQRLHLLSPLEDGGPPGLELNYGSADSPQTMWLELPQAQELQHTIV
FLLD-GSMTST---QWPGN--

MGGSKGKAPQRRARPGRPASVEQESGSASADS-APSRDRRLARGKAHKTKPAKNPEATKG
KGTTEGRRKPTEEGNHHCRGTR-----E--RQGSS-QGRGHRSTGSREPGDSHEELPEEQ
KLPGEEEWTVKRGRR-R--RKEQGPSAPRGHRETSGRDGDTSGGDGGSSCLDSEHQEALD
SSSQGGGASEQPIKAKTSDTSSEGALIRRPES------TGGSNHHGNGGHALELQSRKGP
SGTRAQGASDDSRTDTDSSPWWSGHRRRPRKTP--GTSSRIPEFQETELAREAANSCTSA
PRGSQGPGDCKVIADTSDVGKQPKAELQGTEPEKVE--APRAQRLQVGEVAGKVPVAVSE
SDTGAREGAGAGDRRPRDPAPLAALVVLRKLRTRAPAGTSPQVAGGLHGSLKARLQRAAR
ALGLLRWLRLRVEQR----RGDARRASPQER-----------------------------
----------------------------------------------------EERGRERA
LEARG-GVPGPRRWLALRLACRAV-LREPPRAPPGGSPSPPQALNSSGSDR-ASAIEDAA
PDPKFAVVFPRIHSAQE-SCSGPS-GA--STDAPTGEGA-------AEYR--EEQGASEE
GVVRSRQAPSFSPSAPSGTSPEEN--RSEAEPENPEVKTPVHWAQGSTPCVDPGLGA-DT
LLPQLTLETRLR-QNSP--CRSPRERWEPEDDAEAALERDLELSIRKDLEMPPFPGAKTG
SLPEGLEDI

PF00063 // ENSGT00920000148963_7_Domain_0 (790, 1533)

EDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPLLLALNPHQALPLFSPEV
LASYHPRKAPNTTPHIFAIGAAAYS-LCQSSGQDPCILLGGHSGSGKTETAKKILELLSS
LGQKQTEARGAQLKDILPVLSSFGHAKTILNANASRFGQELRLCLQQGVTVGASVSHYLL
EASRVVFQAQAERSFHVFYELLAGLDPMEREQLSLQGPEAYYYLNQ-GRACRLRRKDDAQ
DFKGLVEALRVLGLCAEELTEVWAVLATILHLGNICFSSSERESQEVAAVSSWAEIHLAA
RLLQVRPERLEGAVT----KRVMDTPYGRVSRSLPVESAIDAR-DALAKALY-TRLFNWL
LKQINVRLAPPREADSVGTITVVDAYGFEALRV--NGLEQLCSNLASERLQLFSSQRLLA
QEEEECQREMLSWVPIPQ---PPPRECCLELLVGQPHSL-LSILDSQTWLAQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGDHPSYAKPQLPLPIFTVRHSAGAVTYQVHKFISRNRDHLDSAMVEMLGQSQLQL
VGSLFQE-----------AEP-KAGREQSKPTLASRFQRSLGDLLARLGR-SHVYVIHCL
NPTPGKLPGLFDVGHVAEQLRQAGVLEVIGARSAHFPVRVPFQLFLA-RFRALGSGRQEA
LSDQERCGTILSQVLGAESPVYHLGTTQV--LLQEQGWQQLEQLWAQRRSQALLTLHRGL
RACITRQRLR--L--LPRMQARV-RGLQA-------------------------------
------RKRYLRRRSALGQLNTILLVARPLLQ--RRQRLQL-----GHSRGPHSGEAGGK
LSSMDLGRLEIPAQLAALLETAEDHQAALPGSITESLPPEIPVRPSLTLPPDIDQFPFSS
FVSSNFQKPYLPRPGQL-LDEPLTRMDGENPQQALEINRVMLRLLGEGFLPPWQEQTMG

PF00784 // ENSGT00920000148963_7_Domain_3 (1800, 1903)

T
FLIRKAQHRPGLRDELFSQLVAQLWQNPDEQQSQRGWALMAVLLSSFSPTPALQKPLLKF
VSDQAPRGMAALCQHKLLGALEQTPLAPMASRAHPPTQLEWK

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGLRRGRM--------AL
DVFTFNEESYSAEVESWTTGEQFAGWILQSRGLEVPPRGWSVSLHSGDAWQDLAGCDFVL
DLIGRIEDLGD----PAGPHSYPITPFGLA-------------------ENIPPAPGVQA
PSLPPGLPPGPAPVL-PGR-GPPG---------------------EARK-PG-NLDGFL-
--DHLFEPVLSPGVSDLEQGWALSSRMKGGGSIGPTQ-QGYPM-VYPGMVQAPGYQPAM-
---IPAPVPMMPAVGTVPTIPAMMVPPQP------QPLLPSLDSRQLALQQQNFINQQAI
ILAQQMTTQAMSLSLEQQNQRRQ-HQAQA----------------SGPATQAPPSATAPK
LKKLP--------TPQEKPES--DLEPSDV----------CFREDTPE-EAEVRPQRPRS
FQQKRDYFQKM---GQE----PIKMKTVKPPAKVQIPQEETEEEE---EE----------
--E---TRAELP-PPHPPPVVK-KPLKPSR------------AKAVKEGEAEPEEDEVPA
QGREPTMQSSNSTPQRPQPSR-APTVQSSNSTP-QRPQPSREIRNIIRMYQSRP--GPVP
V-----------PVQPTR--PVKTFQKKNDPKDEALAKL-----------G-----INGA
HSPPSTV--SPNLEKSSPPEVAPKPKARPRLEPSLSIQEKQGPLRDLFGPCSPSPPTTPA
PPPP--PPPALPLPLPEEPKTLPVESRALTEPMKDQGISTQLLVPSGSVCFSYTGASWKL
FLRKEVFYPRENFSHPYCLSLLCQQILRDTFAESCIRISQEERHRMKDLLGDLEVGLDSL
ETVEESIRKRIVVAARDNWANYFSRIFPVSGESGSDVQLLGVSHRGLRL---LKVTQDSS
------FHLD--RLKTLCSYSFAEVLGVECRSSSILELSLKNEQLTLHTAQARAIKAMVE
QFLRE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDHSLLS-FHRGDLIKLQPAVTLEP----------
------------------------GWQFGSAGGRSGLFPADMVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3160)

PAAAPDFSFSLGHRNS
WQRKSKPQ--------HLKEPRPTHPRSQ---EPSEGSEATSFTAYSSLSADSHNYTMQE
FALRYFRKPHTL-------LTQASRGAKEKVAANLIQYTK----DPIQESLICLSDEDTN
RKAVAGFKALMQFMGDQPKPRGTDELALLYELLKLCQ--

PF00784 // ENSGT00920000148963_7_Domain_5 (3160, 3253)

-DLRDEMYCQVIKQVTKHPQP
KHCALGWSILSLFTGFFSPSTTLMPYVTKFLQDSS-----PSQELARSSQENLQRTVKYG
GRQKLPPPGEMQ

ENSGT00920000148963_7_Linker_5_6 (3253, 3354)

AFLKGQAVRLLLIHLPGGVDYSTNIQTFTVAGEVLEELCGQMGITDSQ
EVQEFALFLIKG----EGELVRPLSSNEYLNSVVTD-QDMSLHSRRLGWETPL

PF00373 // ENSGT00920000148963_7_Domain_6 (3354, 3505)

HFDHPTY
TETHYGQVLRDYLQGKLMASAQ--ADAQLARLAALQHLRKASK-GPPSEE-ELLAYIPKP
LQ----WQVDRANIKSLVDQELRQLQGHSPQRAQIDFIE---------------------
------------TTAQLPLFGYTVYVVLRVSKLVLPGPVLLGLNRQHLVLMEPSS-----
---QKLCCSIPLKDLQRLHLLSPLEDNGPPGLELNYGSADNPQTIWLELPQAQELQHTIV
FLME-GSMSSM---QWPGLS-

MGKNQRKAPQRLERPGRPASGEQESGSASADR-APSRERRSDRGQADKARPAAEPATAGG
QGTAGGRRKPTAEENGGCRRPGAGLSPEAPERQTSAQRQGRGPRGGR------AGRLEEG
SLSRREGL----GGRRRRKRKDQGSLAPRGRRTPRSLNGDTSGGDGGSSCPDSDTREAQE
SGSDEGQDHE--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------RADEGRGRERADEGRGRE---------RADEGRGRERA
DEGRG-REPGLRHRLALRLA-GLAGLGGMPRAPPGG--RSPQVPASPVPDD-PFDLEDET
PDPKFAVVFPRIHRAGPASSSRSSEEA--SADAPTGEGRGWPRAGSWGHS--EGCRAGGE
GVSGLRPGSLLAPTAPDGPSLDESGSSSEAELETLNDEPRVHWAQGSGPREGPRLGA-AV
LLPRLALETRLQQEGDPGLRGSLREQWEPEDEDEAVLERDLELSLGPGLEVPPFPGAKGR
SLGDGLEDMEDLA-----------------------------------------------
-----------RLRHIFAIVASAYD-LAQNTGQDPSILLRGHSGSGKTEAAKKIMQFLSI
LEQDQTGNRECQVEDVLPILSSFGHAKTILNANASRFGQIFCLYLQQGVIVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDSIERERLSLQGPETYYYLNQVGGACRLQGKEDAQ
GFEGLACPA--WGVCPF------------LKQRSPCP---SLSS

PF00063 // ENSGT00920000148963_7_Domain_0 (1065, 1533)

QEVAAVSSWAEIHTAA
RLLRVPPECLEGAVT----RRVTETPYGQVSRCLPVESAIDAR-DTLAKALY-SRLFHRL
LRRTNARLAPPGEGGSIGTVTVVDAYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEE------------------P-LRESCLDLLVDQPHSL-LSILDAQTWLSQTE------
-----------------------LGSCCPGFSA-----MVQSRLTATSTSQATDHTFLQK
SHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQP
----VQE-----------AEP-QSRGGQGRPTLASRFQQALGDLIARLGR-SHVYFIQCL
TPNPGKLPGLFDMGHVTEQLHQAAILEAVSTRSANFPVRVPFEAFLT-SFWALGSEGQED
LSDREKCGAILSQVLGAESPLYHLGATKV--LLQEQGWQWLEELRDQQRSQALVNLHRSF
HTCISRQ--R--I--LPQMQARM-RGFQARSAGVGARAEVGGVS-LDS----SFH---PC
-LFPASRKRHLRRRAALGQLNTILLAAQPLLS--RRQRLQLG----HWQGWHSSERALER
VPSMELGRLEIPAELAVMLKTAEGRQDALAGSITECLPPEVPARPSLTLPTDIDRFPFSS
FVSIGFQEPSLPRLGQP-LAKPLTQLDGENPQHALDINKVMLRLLRDGSLESWQRQTM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1903)

GT
YLVRQGQSRPGLRNELFSQLVAQLWQNPDEQQSQRGWALMAILLSAFPPLPVLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQSQLALGATRAHPPTQLEWL

ENSGT00920000148963_7_Linker_3_4 (1903, 2895)

AGWRRGRM--------AL
DVFTFSEECYSAEVESWTTGEQLAGWILQS----------------RDAWQDLAGCDFVL
DLISQTEDLGD----PARPRSYPITPLGSA-------------------EVIPLAPGIQA
PSLPPGPPPGPAPTL-PSR-DHTG---------------------EVQR-SG-SLDGFL-
--DQIFQPVISSSPSDLEQSWALSSRMKGGGAIGPTQQG-YPL-VYPGMIQMPGYQPGM-
---VPAPMPMMPAMGTVPAMPAMVVPPQP-----PQPLLPSLDAGQLAVQQQNFINQQAL
ILAQQMTAQAMTLSLEQQTQQ---RQRQARASEA--------A------SQASPSAVTSK
PRKPP--------TPPEKPQR--DLESEGG----------CLRET-SE-EAEDRLYRPKS
FQQKRNYFQKM---GQP----QITVRTMKPPAKVHIPQAETQEQ-------EEQ------
-EEQEVETRAVP-SPPPSPIVK-KPLKQGG------------AKAVKEAEAEPAKETSAK
GRGQG-----------PAQGR-GTMVHSSDSKS-KRPQPSREIGNIIRMYQSRP--GPVP
V-----------PVQPSR--TPKGFPKKIDPKDEALAKL-----------G-----INGA
HSSPPML--SPGPGKGPPPAVAPRPKAPLQLGPSSSIKEKQGSLLDLFGQKLPTAQTP--
-----PPPPAPPLPLPEDPGTLSAEHHCLTQPMEDQGVSTQLLAPSGSVCFSYTGMPWKL
FLRKEVFYPRENFSHPYYLRLLCEQILRDTFSESCIRISQNERRKMKDLLGDLEVDLDSL
TTTEDSVKKRIVVAARDNWANYFSRFFPVSGESGSDMQLLAVSHRALAHDPGLEVGAGGK
------MTPA--HARPLR--SFAEVLGVECRGSSTLELSLKSEQLVLHTARARAIEALVE
LFLSE---LKKDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDNCSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSAGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3148)

PAAAPDFSFSKEQRSG
WHGGQLSNGEPGLARWDRASEVRKMGEGQP------------------------------
----------------------------EARPMASSLWPQ----APIQESLLSLSDD-VS
KLAVASFLALMRFMGDQSKPRGKDEMD

PF00784 // ENSGT00920000148963_7_Domain_5 (3148, 3253)

LLYELLKLCQQ-EKLRDEIYCQVIKQVTGHPRP
EHCTRGWSFLSLLTGFFPPSTRLMPYLTKFLQDSG-----PSQELARSSQEHLQRTVKYG
GRRRMPPPGEMKAFL--------------------------VAAEVQEELCREMGVTEPQ
EVQEFALFLIKE----KGQLVRPLQPAEYLNSVVVN-QDVSLHSRRLHWETPLHFDNSTY
ISTHYSQVLWDYLQGKLPVSAK--ADVQLARLAALQHLSK-----------DLLAYMPKQ
LQ----RQVNTGLHQEPDGSELRRLEGHSPQEHRSADAHCSGV-----------------
------------------------------------------------------------
-----LWARAEARGW----LGSPLV----TG-----------LSLWAG----PGAAIHHC
HLIDRSA-SC---TEWPSVN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------T

PF00063 // ENSGT00920000148963_7_Domain_0 (757, 1529)

FGGPLLLALNPHRPLPLFSPEVLA
----SYRPRKAPN-----------------------------------------------
-----------TTPHIFAIVASAYG-LSQSTGQGTCILLSGQSGSGKTEASKKIVQFLSS
LEQEQMRDRGCQLDGVLPLLSSFGHAKTVLNANASRFGQVLCLCLQQGVVVGASVSHYLL
ETSRVVFQAQAERSFHVFYELLAGLDPMEREQLSLQGPETYYYINQ-GQACRLQGKEDAQ
DFTGLVKALQVLGLRPEELTTVWAVLASILQLGNICFSSSERESQEVAAVSSWAEIHTAA
RLLRVPPERLEGAVT----RRVMETAYGQVWRSLPVESAIDAR-DALAKALY-SRLFTWL
LRRTNARLAPPGKGGSTDTVTVVDVYGFEALRV--NGLEQLCNNLASERLQLFSSQMLLA
QEEEECRRELLPWVPIPQ---P-PWESCLDLLADQPHSL-LSILDAQTWLSQ--------
---------------------------------------------------ATDHTFLQK
CHYHHGGHPCYAKPQLPLPIFTVRHYAGTVTYQVHKFLNRNRDHLDPAVVEMLAQSSLQL
VGSLFQE-----------AEP-PSGGGRGKPTLASRFQHSLGDLMAQLGR-SHIYLIQCL
NPNPGKHPGLFDVGHVAEQLRQAGILEAVCARSANFPVRVPFQAFLA-RFRALGTEGQGE
PSDRERCGAILSQVLGAKSPLCHLGATQV--LLQEPGWQQLQQHWAQRRSQMLLTLHRGL
LTCISHQRLR--L--LPRMQARV-HGLQA-------------------------------
------RKRYLLRRAALGQLHTILLVARPLLW--RRRRLQLG----HWCGWHGG-RASEK
VPSMELGRLEIPAELAVMLKTAEGRQHAVAESITESLPPEVPARPSLTLPLDIDQFPFSS
FVSISFQEPSLPSPGQL-LAKPLTRLNGENPQHALDINKVMLRLLGDGSLPPWQEQIM

PF00784 // ENSGT00920000148963_7_Domain_3 (1799, 1901)

GE
YLVRQGQRRPGLRDELFSQLVAQLWHNPDEQQSQRGWALMAILLSAFPPMPTLQKPLLKF
VSDQAPRGMAALCQHKLLGALEQMQLAPESARAHPPTQLE

ENSGT00920000148963_7_Linker_3_4 (1901, 2895)

WTAGRRRGRM--------AL
DVFTFNEECYSAEVESWTTGEQLAGWILQSRGLEVPPRGWSVSLHSGDSWQDLAGCDFVL
DLIGQTEDLGD----PAGPHSYPITPRSLA-------------------EDIPPAPGVQA
PSLPPGPPPGPAPTR-PIR-SHTG---------------------KART-PG-GLDGFL-
--DHLFEPVLSGGNSDLEQGWALRGRMKGGGAMGPMQPGSYPM-MYPGMVQMPGYQPAM-
---MPAPMPMMPAMGVVPPMPAMVVPPQPQ----PQPLPPSVDARQLAVQQQNFINQQAL
ILAQQMTTQAMTLSLEQQTQQRR-RQRQAPAQAP--------VPEAASPPPPPPPAITPK
PKKPQ--------VPQEEPER--EPESVDG----------CLRQETLQ-EAEDRPQRPKS
FQQKRDYFQRM---GQQ----QIKVKTVKPPAKVQIPQGEEQEEEEEEER----------
---PKAVPSPPP-PPPPPQVVK-KPLTQGG------------AKATKEAEAEPTQEVGP-
--GSD-----------RLAQG-RAVVRSSDPAP-QRAEPSREIRNIIRMYQSRP--GPVP
E-----------PVQPSR--PPKNFMKKNNPKDEALAKL-----------G-----INGA
YSSPAML--PPSPGKGPPPAVAPRPKASPRPGSSTTIKEKQAPLREVFGPTPPTAQAP--
-----PPPPAPPLPLPGDLGTPSAEPRGSTVPMGDQGVSTQLLVPSGSVCFSYASTSWKL
FLRKEVFYPRENFSHAYCLRLLCEQILRDTFAKSCIRISQDERRKMKQLLGDLEVGLESL
DTTEDSVKKRIVVAARDNWANYFSRIFPVSGESGSDMQLLGVSHRGLRL---LKVTQGPS
------FYPD--QLKTLCSYSFAEVLGVECPDSSTLELSLKSEQLVLHTARASVIKAMAG
CFLTRSLACLQDSG

PF07653 // ENSGT00920000148963_7_Domain_4 (2895, 2985)

YVI-ALRSYITDDSSLLS-FHRGDLIKLLPVATLE-----------
-----------------------PGWQFGSTGGRSGLFPADIVQ

ENSGT00920000148963_7_Linker_4_5 (2985, 3147)

PAAAPDFSFSSEQRNG
RHKK--------SGLWDRAPEHPAFPQSQAHSEDSEATSLPPSMAYLSVFTDSHNYTMQE
FALRYFRKPQAL-------LHQTGGGAEQKAPASLVQYTK----APIQESLINLSDEGMN
RQAVESFQALMQFMGDQSKPRGKGEM

PF00784 // ENSGT00920000148963_7_Domain_5 (3147, 3254)

ELLYELLKLCQE-ENLRDEIYCQVIKQVTGHPRP
EHCARGWSFLSLLTGFFPPSTTLMPYLTKFLQDSG-----LSQELARTSQEHLQRTVKYG
GRRQLPFPGEMQA

ENSGT00920000148963_7_Linker_5_6 (3254, 3355)

FLKGHTVRLVLIHLPGGVDYKTNIQTFTVAGEVLEELCGQMSIMDPQ
EVQEFALFLIKG----EGELVRPLRPDEYLNSVMVD-KDVSLHSRRLGWETQLH

PF00373 // ENSGT00920000148963_7_Domain_6 (3355, 3505)

FDNPTY
ISTHYSQVLRDYLQGKLLVSAQ--AEDLLARLAALQHLSRAFQ-DTP-SEQDLLAYLPKT
LQ----WQVRRATIRMLMGQELRRLKGCTSQEAQTSFIE---------------------
------------AVRQLPLFGYTVYVVLRVSEVALPGPGFLGLNRQHIILMDPSS-----
---QKLCCSVALRELQRIHLLSPLEEQGSPGLELNYGSADSPRTIWFELPQAQELKHTI-
---------------------