Query Results 

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------------------RDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGH----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 470)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNRDDDTLELS

ENSGT00920000148945_8_Linker_1_2 (470, 1253)

IMPKDRTILAQ
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAAPARVSTRATMVPEPTSALPSDPR
SPAAWSDPGLRVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPPARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRASA-RTP
ACPTRDLPGPQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RVVRPEPST-RSLEPPAEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDQSP-------EPEASGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGR---
GLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDVTFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGFRTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PAHYYETLKFLVGHLKTIADHSEKNKPRGGKHRTYFFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------SATCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGASAPGA-----------
--QERPQGPL---------RAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAG-----GRRAGAGDEADDERSELSHVETDTE------
GS-GPGGRLARRPSFSSHHLMP----CDTLARRRLARARPD-SEGAGRG----SPRARSR
------LGS-ASSAA-GVAAAPVAA-----------LGSAASRMEALRLRLRGTSDDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPDP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASLPPMPGDPGA----------LQSQPPRRSAASR
LHQCL

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-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSPR------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGG---GS---------------------------------
--------------------------------------------SPRPRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKDAGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPARVSTWATMVPEPVSALPGDPR
SPTAWSDPGPRVPSAT-RAHLDNSSLGMSQPRPSPGAFPHLPSEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEEVTAHRPWPCST
SQDALSQL-GRESWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWASQRPSA-RTA
ACASRDLPGPQ--------APPPPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPDAAEPP-RGVRPEASA-RALEPPADDRRDEVVLRQKPPTGR
KIQLTPARQMNLGLGDESP-------EPEASGRGDRLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRPLR
RLPDRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLCYK
QILTKKGKKA---GS--GLRQWKRVYAALRARSLSL-SKERREPGPAA--GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSTA---
RGLRAQDQPTGSK--DDSAATSKTPWSINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGS--
D------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRRDA-------RGLGSSTDDDS-EQEAHKPGTGVSAPEA-----------
--QGRPEGQLPGAAVPE---APGRLS--------------PPAAPEERP---------AA
DTRSIVSGYSTLSTMDRSVCSGAG-----GRRAGAGDEADDERSELSHVET--DTEGGAA
GA-GPGGRLTRRPSFSSHHLIP----CDTLARRRLSRSRPDGEG-A--GAGRGAPRAAEL
------PGS-ASSSSQESLRPPAAA---------AALGSRPSRIEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGSPEP------ASP
RAHSDNKDSGLSSLESTKARAPSSATSLPPAPGDPGA----------LQSQPLRRSATSR
LHQCL

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----------------------------------------------------MD

PF00595 // ENSGT00920000148945_8_Domain_1 (415, 471)

TIFVKN
VKDDGPAHQAGLRTGDRLVKVNGESIIGKTYSQVIALIQNS-DDALELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1252)

MPKDEDIL-Q
LAYSQDAYLKGNQPYSGEARSIPEPPPLCYPRKTYASQPRASSRVTMVSEPHSAPPTDHW
RPSPWSEPGYRAPPSC--PHPDNASFGMSQPRPNPSAFPRLAPDPRTSRAF-----QDPG
VRAPPSKLECQQALSHWLSNQVPRRSG-EGRCPVMPPRARSVSQDRLGDVVAHRPWPCSA
SQDTLCHL-GHEGWH-RARSDDYLGRFVRSAEALGPGTLVSPRFEHSGWVPQRTPT-RPP
TCLPQDPPGPK--------PPAQPTHPSLDDAGY-IGYRSYSPSFQRRTGLLQALSFRDS
PFGGLPTFNLPQPSAPHSAESSEPL-RVTRPEPNT-QPPELPPEERREEVVLRQKPPTGR
KAQQPSPRQMNFGFGDETS-------EPESSGQGEHPSRKVAPLAAAEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLKAKHVPASAVVSSAMNSAPVMG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFREEGRILR
RLPNRVPSLRMLRSFFTDGSLDSLGTSEDA---PSKRHSTSDLSDMTFSDI

PF00169 // ENSGT00920000148945_8_Domain_2 (1252, 1377)

RREGWLYFK
QILTKKGKKV-----GGGLRQWKRVYAALRAHSLSL-GKERREAGT-AAG-----AG-EE
ETAPVCI--SSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRE

ENSGT00920000148945_8_Linker_2_4 (1377, 1516)

NSRA
E---GEDPGFANQALISKKLNDYRKVSHISGPKADSSPKSSRVIAGLKSELLKQNI---P
RSPRTQDLPSGTK--DDSAATSRAPWGINIMKKNKKPSPRAFGVRLEECQPAADNQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVSACCRMVEARGLESMGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EEKGERTPVDEKESQ-SVPNIEYLLPNIGRTVPPGEAGSD-
-------SINCGSTKSKVIALYEK--MGKE------------------------------
------------------------------------------------------------
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-----

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----------------------------------------------VEGAEGMSLD-LPL
MPESLP---RPPELPLGPRDGCSPR------RTLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGG---GP---------------------------------
--------------------------------------------SPRPRLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKN
VKDAGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEVRSIPEPPPICYPRKTYAPPARVSTWATMVPEPVSALPSDPR
SPTAWSDPGPRVPSAT-RAHLDNSSLGMSQPRPSPGAFPHLPSEPRMPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEDVTAHRPWPCST
SQDALSQL-GWEGWH-RARSDDYLSRVTRSAEALGPGALVSPRFERCGWASQRPSV-RTS
ACPPRDLPGPQ--------GPPAAGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEAAEPP-RVVRPESST-RALEPPSEDRRDEVVLRQKPPTGR
KIQLTPARQMNLGLGDESP-------EPEASGRGERPGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPDRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF00169 // ENSGT00920000148945_8_Domain_2 (1253, 1377)

REGWLYYK
QILTK---KGKKAGSG--LRQWKRVYAALRARSLSL-SKERREPGPAA--GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRE

ENSGT00920000148945_8_Linker_2_4 (1377, 1516)

NSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAV---
RGFRTQDQPAGSK--DDSAAAPKTPWSINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGSAT
D------STTCSSAKSKGSWAPKKE------LYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGAPAPGP-----------
--QGQPEGQLPGAAAPE---APGR--------------LSPPAAPEER-PAADT---R--
---SIVSGYSTLSTMDRSECSGAG-----GRRAGAGDEADDERSELSHVET--DTEGGAA
GA-GPGGRLARRPSFTSHHLIP----CDTLARRRLSRSRPDGEG-AGTGR-GGPRA-AEL
------PGS-ASSSSQESLRPPAAAAT--------ALGSRPSRIEALRLRLRGTADDM-A
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGTLEP------TGA
RAHSDNKDSGLSSLESTKARATSSAASLPAASGDPGA----------LQSQPLRRSATSR
LHQCL

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---------MNHGFGDESP-------EPEASGRGERQARKVAPLTTTEDSLASIPFID--
------------------------------------------------------------
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-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
HLPARVPSLRMLRSFLTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTK---KGKKAGGG--LRQWKRVYAALRARSLLL-SKERREPGPAVA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQEQPAGNK--DDSAAAPKAPWGISIIKKNKKTSPRAFGIRLEECQPAIENQ----
-------------HV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSAD
L------LEI--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPKDGCSPG------RPMPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAIHCSLKVEACLGSLGWGS-----------------------------------
-------------------------------------------------PGPM

PF00595 // ENSGT00920000148945_8_Domain_1 (414, 471)

DTIFVKN
VKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-ADTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPAGLSAWAMMVPEPTSALPSDPR
SPASWSDPGFRAPPAA-CTPLEPSSSGMSQPRPSLGAFPSLPP--------------EPN
SRALPSRLECQQALSHWLSKQVPRRAG-QSRCPAMPPRARSASQDRLEDMSAHRAWPCST
SQDALSHL-GQESWH-RARSEDYLGRATRSAEALGPGALGSPRLERCGWASQRPAATRSA
ACPPRDLPGPQ--------SSPAPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQTPTPFPPEASEPP-RVSRPEPSA-GTLEPPAEDRREEVVLRQKPPTGR
KSQLGPTRQMNLGLGDECP-------EPEASGRGERLGRRVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAVTTERSKSCDDGLNTFRDEGRVLR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDTDA-PSKRHSTSDLSDTAFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLSYK
QVLTKKGKKA-----GGGLRQWKRVYATLRARSLCL-SKERREPGPAAAGAAAAGAGEEE
AAAPVCI--GSCLVDISYSDTKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHGSGPKAESSPKVSRGLGGLKSEFLKQSAA---
WALRTQEQPAGGK--DDNMAAPKTPWGINIIKKNKKATPRAFGVRLEECQPATENQ----
-------------HV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRVVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTNDKYNDFIEANRIEDARERMKTLRKLIRDL
PGHYYETLKFLVAHLKTIADHSEQNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPASDPGSAA
V------S-------PQASWAPRKE------PYAPEMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSXXXXX-XXXXXXXXXXXXXXXX-----------
--XXXXXXXXXX---------XXX------------------XXXXX----------XXX
XXXXXXXXXXXX-XXXXXXXXXXX-----XX-X-----XXXXXXXXXXXXX--XX----X
XX-X-XXXX-----X-XXXXX--------XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX
------PGS-ASSSSQESLRPPAAAVA------L---AARPSRLETLRLRLRGTADDM-A
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLPDLNFNEWKEVGAQGT------------
--AGDNRDSGLSSLESTKARASSSAASLP--PGDLGS----------LQGMTPRLAPASR
LHPCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPE---PRPPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAAPARVSTRATMVPEPTSALPSDPR
SPAAWSDPGLRVPPAT-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPPARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRASA-RTP
ACPTRDLPGPQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RVVRPEPST-RSLEPPAEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDQSP-------EPEASGQGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDVTFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGFRTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PAHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------SATCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--QEQPQGLLPGAIAP---EAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGVG-----GRRAGAGDEADDERSELSHVETDTE------
GA-GPGGRLARRPSFSSHHLMP----CDTLARRRLARARPDVSEGVGRG----APRVPEP
------PGS-ASSSSQESLRPPVAA-----------LGSRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKVRAPSSAASLPPTSGDPGA----------LQSQPPRRSATSR
LHQCL

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---------MNLGFGDESP-------EPEASGRGERPGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTK---KGKKAGGG--LRQWKRVYAALRARSLSL-SKERREPGPAA--GAAAVGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRIQDQPAGSK--DDSVAAPKTPWGINIIKKNKKVAPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDNKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSAD
L------LEI--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPE---PRPPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
VCPTRDLPGRQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RAVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLKTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--QERPQGPLPGAVAP---EAPGRLSPP--------------AA---------PEERPPA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GVA
GA-GPGGRLTRRPSFSSHHLMP----CDTLARRRLARGRPDG-EGASRG----GPRVPEP
------PGS-ASSSSQESLRPPAAA-----------LASRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASLPPAPGNQGA----------LQSQPSRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MD

PF00595 // ENSGT00920000148945_8_Domain_1 (415, 471)

TIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPAARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
ACPTRDLPGRQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RAVRPEPST-RALEPPVEDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESL-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF00169 // ENSGT00920000148945_8_Domain_2 (1253, 1377)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRE

ENSGT00920000148945_8_Linker_2_4 (1377, 1516)

NSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQDLTAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSEE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--QERPQGPLSGAVAP---EVPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GAA
GA-GPGGRLTRRPSFSSHHLMP----CDTLARRRLARGRPDG-EGVSRG----GPRVPEP
------PGS-ASSSSQESLRPPAAA-----------LASRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASLPPAPGDQGA----------LQSQPSRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------FPPEASEPP-RAVRPESST-RTLEPPTEERRDEVVLRQKPPTGR
KVQLPPARQMNLGFGDEST-------EPEASEQGERPGRKVAPLTTAEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLS
TSPSSPTFTFALGRHYSRDCSESPYAPASSWP-LLSGPREDS----GDVLTCRGQARPLR
PH-NIH---PKLPPVVSLQSLDSWGTSEDADA-PSKRHSTSDLSDSTFSD

PF00169 // ENSGT00920000148945_8_Domain_2 (1251, 1379)

VRREGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAA--GAAVAVAGED
EAAPVCI--GSCLVDISYSEIKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENS

ENSGT00920000148945_8_Linker_2_4 (1379, 1516)

RA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKSDAA---
RSLRTQDLHTGSK--DDSATTPKAPWGINIIKKNKKVAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1670)

PLIVATCCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIIETLIQHSDWFFSDE--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPADPGS--
D------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGAPLPGT-----------
--QDLPEGQLPGAAAPE---VPGRLSPS--------------AAPEER---------PAA
DTRSIVSGYSTLSTMDRSVCSGAG-----GRRAGAGDEADDERSELSHVET--DTEAGAA
SA-GPAGRLARRPSFSSHHLIP----CDTLARRRLSRSRPDGEG-AGR----TGPRVAEL
------LGS-ASSSSQESLRPPASAAA---------QMSRPSRIEALRMRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGP
RAHSDNKDSGLSSLESTKARASSSAASLPPAMGEPGA----------AQSQPPRRSAAAR
LHRCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-XPPESAVHCSLKEEENGGRGG--------------------------------------
------------------------------------------GSSPR

PF00595 // ENSGT00920000148945_8_Domain_1 (408, 471)

HRLEPMDTIFVKN
VKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARVSTWAAMVPEPLSALPGDPR
SPAAWSDPGPRIPSTA-RSHPDHPSLGMSQPRPSPGAFPRLPPEPRTPRAF-----PEPG
SRAPPSRLECQQALSNWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEEVTAHRPWPCST
SQGALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALLSPRFERCGWASQRPSA-RTP
ACAPRDLPGPQ--------APAPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLQALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RVVRPEPST-RASEPPAEDRRDEVILRQKPPTGR
KVQLPPARQMNLGFGDESP-------EPEASGRGERPARKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF00169 // ENSGT00920000148945_8_Domain_2 (1253, 1377)

REGWLYYK
QVLTKKGKKA-----GGGLRQWKRVYAALRARSLSL-SKERREPGPAAA-GAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRE

ENSGT00920000148945_8_Linker_2_4 (1377, 1516)

NSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSTA---
RGFRTQDQPAGSKAPDDSVSTSKTPWGISIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERLKTLRKLIRDL
PGHYYETLKFLVSHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDS--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGEPGSAL
HPSSPLPSSPCALPPSPGSCS--------------SLLLPSFLQRTCWRFKGYSVALRPR
SLTVAGDYKKAGQA-------WGKGQAEL--S-RAVRTSPL-QSSSPRLLTA--------
--YRSPIGK-PLLRRKE---ALVRVLSL----A---------------------------
---------------TSDYLGGVG-----L--AGSG---TQHQAYHSTPSCKRQAGEGAR
GR-G-GGDGREEPPVSSNHLLPLSCPCVSLCVLQSNRDRRGGER-PKKKSAFSCPIQLSF
FLCFLPTGSTTCSSAKSKLRSLAASCLFQSLPSRARMPAPDEPCSAVRLELEGQADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPVS------AGP
RAHSDNKDSGLSSLESTKARAPSTAASLPPAPGDPGA----------PQSQPPRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------QSAGI
TA-WP---PCLPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
VCPTRDLPGRQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RAVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDEAP-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSVA---
RGLRTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSG-
-------ER----RGLGGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--QERPQGPLPGAVAP---EAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GAA
GA-GPGGRLTRRPSFSSHHLMP----CDTLARRRLARGRPDG-EGASRG----GPRVPEP
------PGS-ASSSSQESLRPPAAA-----------LASRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSVASLPPAPGDQGA----------LQSQPSRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------LPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQESWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
VCPTRDLPGRQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RAVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEEADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSVA---
RGLRTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSA-
-------DL----LEI--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKNPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAAPARVSTRATMVPEPTSALPSDSR
SPAAWSDPRLCVPPSA-RAHLDNSSLGMSQPCPSPGAFPHLASEPRTPCAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPPARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRASA-RTP
ACPTRDLPGPQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPTPFPPEASEPP-RVVRPEPST-RSLEPPAEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDQSP-------EPEASGRGERLGRKVAALAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGFRTQDLPAGSK--DDSAAAPKTPWGIHIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NMQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PAHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------SATCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--RERPQGSLPGAVAP---EAPGCLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAG-----GQRAGAGDEADDERSELSHVETDTE------
GA-GPGGRLARRPSFSSHHLMP----CDTLARRRLARARPD-SEGTGRG----GPCTPEP
------PGS-ASSSSQESLRPPVAA-----------LVSRPSLMETLRLRLRGTADDMLA
VRLRQPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNKWKELDGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASLPPMRGDPGT----------LQSQPLRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------REAHLG
T--------AFVCQHRRVTCASVQGLEGRRQETLLSL-----------------------
---------------------ERSGGAGEADGDQKDVGSIPRLFSVCYSESSGQDWPLTT
PVLPQPRVSL

PF15410 // ENSGT00920000148945_8_Domain_2 (1271, 1374)

QKAGSG--LRQWKRVYAALRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQDLPSGSK--DDSAAAPKTPWGINIIKKNKKAPPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSAD
L------LEI--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MPSRVPSLRMLRSFFTDGSLDSLGTSEDT---RSKRHSTSDLSDVTFSDVR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

KEGWLHYK
QILTKKGKKV-----GGGLRQWKRVFAVLRTHSLYL-CKDRREAVSCGPA-----PG-EE
EQ-PISI--RACLVDISYSETKRKHVFRLTTADFCEYLFQAEDREDMLAWIKV

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSKA
E---GEDPGFASQALINKKLNDYRKVSP-AGAKPDSSPKGSRGLG-IRAEFLKQTGTSAP
RSPRQDAAVT--K--DES-SSQKAPWGINIMKKNKKSAPRAFGVRLEDCQPAPDNK----
-------------NV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVEACCKVVEDRGLEYMGIYRVPGNNAVVSSLQEQLNKGATEI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDASERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDK--EDKGEKTPVDEKEAQ-SVPNIEYLLPNIGRTAAPGDAPD--
-------STHSGSAKLKVRGAGAGGRRGRGVEGEREVLPHCLWGRGAQR-----------
-------GPKPCAAVLPGHVAVAEGAVAPRAP-GHPFHLRRRPQEEEVAR----GRMLRQ
QHRRRRGAQRHAGPG---AGGGGGH-----------------GR--------RTGTRPNP
THRE-------------------------------GE-------------RRGTRRYRAG
TG--SGRPFHRIGVFHSVHH--------------------------------GA------
--QSELRG------AVGGREP----RGG------GG------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------LPLGPRDGCSPG------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEE

PF00595 // ENSGT00920000148945_8_Domain_0 (317, 471)

NGGRRG---GGGGGG-----------------------------
-----------------------------------------GPS-SRHRLEPMDTIFVKN
VKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_0_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYALPARASAWATMVPEPISALPSDPR
SPAAWSDPGPRVPPAT-RAHLDNSSLGMSQPRPSPGAFPHHPSEPRTSRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEDVTTHRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATHSAEALGPGALVSPRLERCGWASQRPSA-RTS
ACPTRDLSGPQ--------APPPPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPASFPPEASEPP-RVVRPEPHT-RALEPPAEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGEESP-------EPESSGRGERPGRKVTPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTK---KGKKAGSG--LRQWKRVYAALRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSMA---
RGLRTQDQPAGSK--DDNAAAPRTPWSINIIKKNKKVTPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKNF-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------NEWKELGGGGGPEP------TGA
RAHSDNKDSGLSSLESTKARASSSAASLPP--GDLAA----------LQSQPPRRSTASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-YPPESAVHCSLKEEENGGRGG---AG---------------------------------
-------------------------------------------PSPRHRLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKN
VKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSIMPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARVSTWATMVPEPLSALPGDPR
SPAAWSDPGPRIPSTA-RSHPDHPSLGMSQPRPSPGAFPRHPSEPRTPRAF-----PEPG
SRAPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEEVTAHRPWPCST
SQGALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRPSA-RTP
ACAPRDLPGPQ--------APAPPGPQGLDDLGYIIGYRSYSPSFQRRTGLLQALSFRDS
PFGGLPTFSLAQSPAPFPPEASEPP-RVVRPEPST-RASEPPSEDRRDEVILRQKPPTGR
KVQLPPARQMNLGFGDESP-------EPEASGRGERPARKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIRREGWLYYK
QVLTKKGKQAGSHG----AKVWRWVPARSQAHPLGL-SAQHREPGPAAA-GAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSTA---
RGFRTQDQPAGSKAPDDSVSTSKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERLKTLRKLIRDL
PGHYYETLKFLVSHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDS--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGEPGSGE
S------TGPGRGGEAVGS---------------------AFLGAPDA------------
-------------------------------------------WPGAQP-----------
--CSCPTGPLPAPPPRR---AIAPASAA----SEGWLFLFPKPEPLVTQPLSPAPRPLAV
IVEESRRGYLL--ALATNSSHSVG-----DLPA-----CVSDRGIAQHPSCKRQAGEGAR
GC-G-GGHGREEPPVSSNHLLPLSCPCASLCVLQSNRDRRGGER-PKKKVHHAPRTWGEA
------AGC-LFQSLPSRARMPAPD--------------EP--CLTVSLELAGHYNIYSL
VHYMSDESPEGRNRTGGWIDLESGTVEVESDLCDTGCGEWNENWGEGDLLH------LGG
QPQAEEAAGGAGTGQQHRRRLGAGSASLPPAPGDPGA----------PQSQPPRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------I

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1670)

PLIVEACCKVVEDRGLEYMGIYRVPGNNAVVSSLQEQLNKGATEI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDASERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQ----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPE---PRPPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_3 (471, 1341)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEAAAPRAWPCST
SQDALGQL-GQEGWR-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
ACPTRDLPGRQ--------APPPPGLQGLDDHGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RVVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQINLGFGDESP-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIRREGWLYYK
QILTKKGKKA-----GS------------------------------VAG-AAAAGAGED
EAAPVCI--GSCLVDISYSE

PF15410 // ENSGT00920000148945_8_Domain_3 (1341, 1374)

TKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_3_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQDLPAGSK--DDSAAAPKAPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--QERPQGPLPGAVAP---EAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GAA
GA-GPGGRLTRRPSFSSHHLMP----CDTLARRRLARGRPDG-EGASRG----GPRVPEL
------PGS-ASSSSQESLRPSAAA-----------LALRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------ANA
RAHSDNKDSGLSSLESTKARAPSSAASLPPAPGDQGA----------LQSQPSRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MNLGFGEESP-------EPESSGRVERLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSLK--AGRRSSYLLAITTERSKSCDDGLNTFREEGRALS
P--PK------LPSVVSLQSLDSWGTSEDADV-PSKRHSTSDLSDATFSDIRREGWLYYK
QVLTKKGKLG-----EGSLSQLRALSL----------SRELMSSRMLSALASQASPGEP-
--PPSPQALSE-------------TIHCRTEGGRCDRSLQ--------------------
-------SQTYHLTLISKKLNDYRKVSHSSGPKADSSPKVSRGLGGLKSEFLKQSTARGF
RT---QDQSAGSK--DDSATTPKTPWGINIIKKNKKAAPRAFGVRLEECQPAIENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGSA-
-------DLLEI------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPE---PRPPQLPLGPRDGCSPR------RPFPWQGPRTLLLYKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLRVPPAA-RAHLDNSSLGMSQPRPSPGAFPHLSSEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
ACPTRDLPGPQ--------APPPSGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPASFPPEASEPP-RVVRPEPST-RALEPPAEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEASGRGERLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAVG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGT-----------
--QERPQGPLPGAVAP---EAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GAA
GA-GPGGRLTRRPSFSSHHLMP----CDTLARRRLARGRPDG-EGAGRG----GPRAPEP
------PGS-ASSSSQESLRPPAAA-----------LASRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASQPPAPGDTGS----------LQSQPPRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------RDGCSPG------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGGAAGGGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPWPRALPPPMD

PF00595 // ENSGT00920000148945_8_Domain_1 (415, 471)

TIFVKN
IKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDNLELTIMPKDEDVL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPARLSAWATMVPEPTSALLSDPR
SPAAWSDPGPRVPPAT-LTHPESSSLGMSQPRPSPGAFPHLPEEPRTSRAF-----PEPG
SRALPSRLECQQALSNWLSKQVPRRAG-ESRCPAMPPRARSASQDRLEEVTAHRAWPCST
SQDALSQL-GRESWH-RARSEDYLGRATRSAEALGPGLLGSPRFERCSWASQHPAA-HTT
ACPARDLPGPQ--------ALPAPGLQGLDDIGY-MGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPSFSLAQTATPFPPEASEPP-RVTRPEPNA-LALEPPAEDPREEVILRQKPPTGR
KGPLGPARQMNLGLGDETP-------EPEAGGRGERLGRRVTPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYAKDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDSAFSDVRREGWLSYK
QVLTRKGKDS-----AGGW--WSGSAAATPAP-QPL-EAEGMAGNPSSVP--PAKSGRRE
QGPPGEPRLEQSLG-SASSGPEDHSAMRLRTAGTL---VSGE------GYGSGVEVRPAP
GGPWGAGAGGG-GRWRDEHRFPLFLRSHGSGPKADASPKVSRGLGGLKSEFLKQSAVRGL
RT---QEQSPGSK--DDTTAAPKTPWGINIIKKNKKATPRAFGVRLEECQPAPENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTNDKYNDFIEANRIEDARERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEQNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--KDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGP--
---------GEGWGCGAASWAPRKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-DSLESTKARASSSAASLPPGDLGTLQ-
----------------A-VANASR-------LHPCL------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------A
PHSRTDELLPPHPLPLGPRDGCSPR------RPFPWQGPRTLLLYKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLRVPPAA-RAHLDNSSLGMSQPRPSPGAFPHLSSEPRMPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
ACPTRDLPGPQ--------APPPSGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPASFPPEASEPP-RVVRPEPST-RALEPPAEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------DPEAGGRGERLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------HA

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVE-----STGFYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRNLCC---VLDKYNDFIEANRIEDVWERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKIEP-RNLALVFGPTMVRTSEDNMTDMVTHMPDCY
KIMETLIQHVNWFFSDQVQEDKAERAPVGDKELQ-AVPNIEYLLPNIGRTVPPGDLGSD-
-------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGT-----------
--QERPQGPLPGAVAP---EAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRSGAGDEXX--------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------XXPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASQPPAPGDTGS----------LQSQPPRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQSPASFPPEASEPP-RAVRPESST-RALEPPTEEGRDEVVLRQKPPTGR
KAQLPPARQVNLGFGDEST-------EPESSERGERPGRKVAL-TTTEDSLXXXXXXX--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDVDA-PSKRHSTSDLSDTTVSDVRREGWLYYK
QILTKKGKXX-----XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX-XX
--XXXXX--XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTTARSL
RT---QDLHAGSK--DDSAATPKAPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1670)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PVHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPADPGS--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSSG------RPLPWPGPRTLLLRKSLQDGFGFTLRHFI
VYPPESAVHCILK

PF00595 // ENSGT00920000148945_8_Domain_0 (314, 471)

EEENGGRGGRG-----GG-----------------------------
-----------------------------------------GGPSPRHRLEPMDTIFVKN
VKDGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIGLIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_0_2 (471, 1253)

MPKDEDVL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPTRAPAWATMVPEPISALPPDPR
SPAAWSDPGSRVPSAT-RAHLDNSSLGMSQPRPSPGAFPHLPSESRTPRAF-----PEPG
SRVLPSRLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWASQRPSA-RTS
ACPSRDLT--Q--------APPPSGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQSPASFPPEASEPP-RVVRPDPST-RALEPPAEDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEA--RGERLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAASVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQEQPPGSK--EDSVAAPKTPWGINIIKKNKKATPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSD-
S-------TTCSSAKSKGSWVPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKAAV-----GT-----------
--QEPPEGQLPGPAAEE---APGRLSPP--------------TAPDE---------RPAA
DTRSIVSGYSTLSTMDRSVCSGTG-----GRRAGAGDEADDERSELSHVETDTE-----G
GA-GPGGRLSRRPSFSSHHLMP----CDTLARRRLSRSRAEAEG-LGAGTARAGPRGPEP
------PGS-ASSSSQESLRPPAAAPA------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------VGV
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGA----------LQGLPPRRSAAAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
PSRAGPSPPCLPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKVCHCPGSFHGGG--RLFC-----------------------------
-----------------------------------------ARPSPRHRLEPM

PF00595 // ENSGT00920000148945_8_Domain_1 (414, 471)

DTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEETAAPRAWPCST
SQDALGQL-GQEGWR-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
ACPTRDLPGRQ--------APPPPGLQGLDDHGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RVVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQINLGFGDESP-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAA--AGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQDLPAGSK--DDSAAAPKAPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKVRME---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------AILKL
------PGS-ASSSSQESMRPSAAA-----------LALRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------ANA
RAHSDNKDSGLSSLESTKARAPSSAASLPPAPGDQGS----------LQSQPSRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPE---PRPPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-NDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLTSEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
VCPTRDLPGRQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RAVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSMA---
RGLRTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--QERPQGPLPGAVAP---EAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GAA
GA-GPGGRLTRRPSFSSHHLMP----CDTLARRRLARGRPDG-EGASRG----GPRVPEP
------PGS-ASSSSQESLRPPAAA-----------LASRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASLPPAPGDQGA----------LQSQPSRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MNG---VTFCLVGI
PPRPEP---RHPQPSLGPRDACSPG------PPNLWPGPRTLLLRKNPRDGFGFTLRHFI
VYPPESAVHCGVKEEENGNR----------------------------------------
-----------------------------------------GGPSPRSHLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKN
VKNDGPAHQAGLRTGDRLVKVNGESIIGKTYSQVIALIQNS-DDALELSIMPKDEDIL-Q
LAYSQDAYLKGNQPYSGEARSIPEPPPLCYPRKTYASQARASSRVTMVSEPHSAPPTDHW
RPSPWSDPGYRALPSC--PHPDNASFGMSQPRPNPSAFPRLAPDPRTPRAF-----QDPG
VRAPPSKLECQQALSHWLSNQVPRRSG-DGRCPVMPPRARSVSQDRLGDVVVNRPWPCSA
SQDALCHL-GHEGWH-RARSDDYLGRFVRSAEALGPGTLVSPRFEHASWVPQRSPT-RPP
ACLPQDPPGPK--------PPAQPTHPSLDDTGY-IGYRSYSPSFQRRTGLLQALSFRDS
PFGGLPTFNLPQPSAPHSTESSEPL-RVTRTEPNT-QAPEPPTEERREEVVLRQKPPTGR
KAQQPPPRHMNFGFGDEAS-------ESESGGQGEHPGRRVAPLAAAEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLKAKHVPASAVVSSAMNSAPVMG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFREEGRILR
PWTVWAHQK-MP---------PPRGT----------QPLTSQTRPLVMS-GEKAGYILSR
SSP-------------RRERKWVV---------------------ACASG-----N----
---------------VSMLRSGHTHSPWARSGGRRARRAQAEDRDDMLGWIRAIRENSRA
E---GEDPGCANQALISKKLNDYRKVSHISGPKADSSPKGSRGIAGLKSELLKQNA---P
RSPRTQDPPSGTK--DDSAATSRAPWGINIMKKNKKPSPRAFGVRLEECQPAADNQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVSTCCRMVEARGLESMGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EEKGERTPVDEKESQ-SVPNIEYLLPNIGRTVPPGEAGSD-
-------SINCGSTKSKGSWVPKKEP------YTREMLAISFISAVNRK-----------
-------RKKRSEA-------RGLGSSTDDDS-EQEAHKLGAG-----------------
-VQDGPGGQPPAPRDAG-AP--SRH-------------------SPPRSSKEGTGERPAA
DTRSIVSGYSTLSTMDRSVCSGTEGRG--GGGGGGGDEADDERSELSHVETDTEGGGGPR
PGA--EGRLPRRPSFSTHHLMH----CDTLARRRLSRSRADGDDAGAGGRPSHS------
--PGDLAGS-ASSSSQESLRPPPAAGGK------AALTARPSLTEQLRLRLRGSADDMFG
VKLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGEGGGSLTP--GEGTPA
RPHSDNKDSGLSSLESTKARASSASASTSLQPQA--------GEPASSRSQAPRRTATAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GLDDAGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RVVRPEPGT-RALEPPAEDRRDEVVLRQKPPTGR
KVQLPPSRQMNLGFGDEPP-------EPEASGRGERLGRKVAPLATTDDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSD

PF00169 // ENSGT00920000148945_8_Domain_2 (1251, 1379)

IRREGWLYYK
QVLTKKGKKA-----GGGLRQWKRVYAALRARSLSL-SKERREPGPAAA-GAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENS

ENSGT00920000148945_8_Linker_2_4 (1379, 1516)

RA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSTA---
RGLRTQDQPAGSK--DDSVSTPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1668)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMQTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKXEP-RNLTLVFGPTLVRTSENIMADMVTHM-DRY
KIVETLIQHSDWFFSDN--EDKGERTPVDDREPQ-SVPNIEYLLPNIGRTVPPGEPGS--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GLDDMGY-VGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSSAPFPPEAAEPP-RGGRPEPSAARALEPPPEEPRDEVVLRQKPPTGR
KAPVPPARRVHLGHGDEGA-------EPEASGRGERLGRKVTPLATTEDSLASIPFIX--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXAAAAVAGE-D
--EAALVGIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAARGL
RP---QDQSAGNK--DDGAAPPRTPWGINIIKKNKKTAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1671)

PLIVAACCRLVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRLEDSRERMKTLRKLIRDL
PGHYYETLKFLVSHLKTIADHSEKNKMEP-QNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGER-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------SNG-------ASHP
PLTLPP---CVPQLPLGPRDGCSPG------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGGAAGGGG

PF00595 // ENSGT00920000148945_8_Domain_0 (329, 471)

GGGG----------------------------
-----------------------------------------GGPSPRHRLEPMDTIFVKN
IKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDNLELTI

ENSGT00920000148945_8_Linker_0_2 (471, 1253)

MPKDEDVL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPARLSAWATMVPEPTSALLSDPR
SPAAWSDPGPCVPPAT-LTHPESSSLGMSQPRPSPGAFPHLPEEPRTSRAF-----PEPG
SRALPSRLECQQALSNWLSKQVPRRAG-ESRCPAMPPRARSASQDRLEEVTAHRAWPCST
SQDALSQL-GRESWH-RARSEDYLGRATRSAEALGPGLLGSPRFERCSWASQHPAA-HTT
ACPARDLPGPQ--------ALPAPGLQGLDDIGY-MGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPSFSLAQTATPFPPEASEPP-RVTRPEPNA-LALEPPAEDPREEVILRQKPPTGR
KGPLGPARQMNLGLGDETP-------EPEAGGRGERLGRRVTPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYAKDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDSAFSDVR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLSYK
QVLTRKGKKA-----GSGLRQWKRVYATLRARSLCL-SKERREPGPAA-GAAAAGAG-EE
EAAPVCI--GSCLVDISYSDTKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEVSPGRGG---------------------------------VDQA----------
-EP--AAWAAGAD--GR---------ASLSCSRTPKATPRAFGVRLEECQPAPENQVGFA
APWRRAGQGDRQTRV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTNDKYNDFIEANRIEDARERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEQNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--KDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGPD-
-------FATCSSAKSKASWAPRKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EHEAARGGAPGAPE-------------
--------------------------------------------PPPRAPSPTPPAAPAP
DARSVASGYSTLSSAGRGAR-----------RAGAGDEADDERSEPSLAGTDTEGGAG--
-------ARGRRPSFSSHRLMP----CDTLARRRLARGRADPEG---------P------
--RAPAPGS-ASSSSQESLRPPGA---A------EALGARPSRLETLRLRLRGTADDM-A
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKERGAQGAA---------GA
RAHSDNKDSGLSSLESTKARASSSAASL--PPGDLGT--------------LQAVATASR
LHPCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------ADCPVPI
PPLPVP---FLLQTPVVPRDGGCPSTSPPLDESFHWVGPR

PF00595 // ENSGT00920000148945_8_Domain_0 (281, 471)

TLVIRKS-QHGFGFTLRHFI
VYPPESAVTSVHKEEDGGAVT---------------------------------------
-----------------------------------------DLPSAASQLEPMDTIFVKQ
VKEGGPAQKAGLCTGDRLVKVNGESIIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_0_2 (471, 1251)

MPRDEDIL-Q
LAYSQDAYLKGNEPYRGGAHSIPEPPPVYYPWRTHEPVSGYAPAS-RYHHPNSADATAIR
SPVHSEVP--RGSPAHRDNYPRTAPTSLSQARSF----QGSPSSSDAPRNVSPEPWERLA
SPRWVSPWERHQALCSWMSQQAPRRGS------ALPPRRRSASQDRLGETTHLSNWPHSV
SQDTLHQAPLYESWGHRAQSDNFLAQFGTSAEKLNLSALISPPYEHRIWPQDRPLH-SSQ
A-PSRVRPSQTVSPGLREATKPPQPHPSSGDSGY-IGYRSYSPSFQRRTELLNAFSFRET
AFSGLPTFRTEQYSGSPA---SLPE-RRESAVSASSTDDSCSTQERREEVVLRQKPPSGR
KAT-TAVRQVNLHFPTEVNE----------EAPRERPLQRVPPLPPSEEPLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLRAKHVPASCVVSSAINSAPVIS
ASPSSPSFSFNISRHYSQDCSSIK--SSRRSSYLLAITTERSKSCDDGLNTFREEGRLQR
RVVGRVPSLRMLRSFFTDGSLDSLEANEDG---RSKRHSASELSETEFSD

PF00169 // ENSGT00920000148945_8_Domain_2 (1251, 1379)

VRREGWLLYK
QILTNKGKKV-----GSGLRQ-KRVFAVLRPHLLFL-HKDRPEARGPAPG---------E
EE--QPISILGSLVDISYSETKRKHVFRLTTPDFCEYLFQAEDRDDMLSWVKAIRENS

ENSGT00920000148945_8_Linker_2_4 (1379, 1516)

RM
E---GEDPGFASQALINKKLNDYRKVSI-TGVKQETSPKGSRSLG-IRPDLLWTSGVSAP
RSPKQD---GAAK--AEEAPPSKGAWGINLMKKNKKCPPRAFGVRLEDCQPAAENK----
-------------GV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1670)

PLIVELCCSQVEQKGLEYLGIYRVPGNNAVVSSLQEHLNKGLSES
NIQDQRWQDLNVVSSLLKSFFRKLPEPLFTDDKYSDFIEANRMEDSRERMKMLRKLIKEL
PSYYYETLRFLVRHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHFDWFFSEE--QEKAEKTPVDETNSQ-NIPNIEHLLPNIGRTAGTGENSD--
-------STNSDSAKGKGSWVSRKE------IYARDILSIPFISAVNRK-----------
-------RRKRRDE-------KRFGSSTEEDDSEQEAARAGQVEQKAEAE-----VELRE
T----------------------------------------EESPAQTCSPHGPGERIPV
DARSIVSGYSTLSTLCSEPAS----------SVRGGEEADDERSEFSHMETDTEGVGARE
TD----ERPHSQDSFTSQRLIP----GDTLARRRLGRGRIESKEEPA-------------
--------------------P-----------------------PRNSLRIRPAADDLCV
AALRKPGSPETRRRKSAWRR---HTVVLPGQLTDCNFNDWKEPVPGATV-ASEPGSRLSG
GAWVEGRDSGLSSLESQKAKTSVA------------------------------------
-----

MGSWAETASEGRPRLRGMEPLKVPPPPRPIPSPVGITITVLVSTPVSLWMEGSLSLFSFP
FFQRPFSSSSSLISSAILYPVSVLSASLMLSVSLCSFLTGCVSLRLPFPSFLPLLVLVLG
SVPLSSFLGRSDNRPPRPDPWRPAQTVTPRPPLFRWPCCAFQLPCQRGSQLQPFVPVGYP
GERQRVRPVGNSGGGAKRRPTPSALGPAPPGSRPAPLAVPWPQRRRCRPMNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSPG------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGG--------------------------------------
-----------------------------------------GPSP-RHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARVSTWATMVPEPLSALPSDPR
SPAAWSDPGPRIPSAT-RTRLDSPSLGMSQPRPSPGAFPRLPSEPRTPRAF-----PEPG
SRAPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEDVTAHRPWPCST
SQGALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWASQRPSA-RTP
ACPPRDLPGPQ--------APPPPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RAVRPEPSP-RALEPPVEDRRDEVVLRQKPPTGR
KVQLPPARQMNLGFGDESP-------EPEASGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDAPFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QVLTK---KGKKAGGG--LRQWKRVYAALRARSLSL-SKERREPGPAAAAGAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADASPKGSRGLGGLKSEFLKQSTA---
RGLRTQDQPAGSK--DDSAATPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDN--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGS--
D------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPEEGAPAPGA-----------
--QDRPKGQLPGAALPE---APGA--------------SAPRRRRRSGRPRTRAPSSRA-
--TPPCPPWTA--AF--ARARRAG-----GRARGTRRTTSAAS-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MLAVSPRHH----PLGLRMCLRLL
PPY--M---GSSGLPLGPKDGCSPG------RPLPWQGPRTLLLRKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------------------------------------
-----------------------------------------GGPSPRHRLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKH
VKDNGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPARLSAWATMVPEPTSALPSDPR
SPAAWSDPGPRVPPAA-RTPPEPSSLGMSQPRPSPGAFPHLPSELRTPRAF-----PEPS
SRALPSRLECQQALSHWLSKQVPRRAG-ESQCPAMPPRARSASQDRLEDMTAHRAWPCST
SQDALSQL-GRESWH-RARSEDYLGRATRSAEALGPGALGSPRFERCGWASQRPAA-RTT
ACPARDLPGPQ--------ASPVPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQTPTPFPPEAAEPP-RVSRPEPSA-RALDAPTEARREEVVLRQKPPTGR
KGQLGPARQMDLGPGDECP-------EPEASGRVERLGRRVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIR--AARRSSYLLAVTTERSKSCDDGLNTFRDEGRVLR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDTAFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLSYK
QVLTKKGKKA-----GGGLRQWKRVYATLRARSLCL-SKERREPGPAAAGAAAAGAGEEE
AAAPVCI--GSCLVDISYSDTKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEVSRGP-QARAGRAAGDRRGR----------AGRAAPRAGALT----------AP
LLPSSQDPAGGSL--G--VRAGQTPWGINIIKKNRKAAPRAFGVRLEECQPATENQ----
-------------HV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTNDKYNDFIEANRIEDARERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEQNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERVSGGERWGPRPVPRV----PARG------LWGPL-
-------SLGKGWGRQ-S--RGLASRAPRREPYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EHEVAQAGAPNPAGLEL----------
--WRSSCLSLPSARITG-VQQQTRLSPSLLLLQLCLLFL-SSGTGTPPSSLEGQGQSPAP
WHL----------------CHT---------------------------DLLG-SSWVSL
PGGWDPVPF---------VPLH----CT--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSPR------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGG---GP---------------------------------
--------------------------------------------SPWPRLEPM

PF00595 // ENSGT00920000148945_8_Domain_1 (414, 471)

DTIFVKN
VKDAGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARVSTWATMVPEPVSALPSDPR
SPTAWSDPGPRVPSST-RAHLDNSSLGMSQPRPSPGAFPHLPSEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEEVTAHRPWPCST
SQDALSQL-GREGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRPSA-RTP
ACAPRDLPGPQ--------APPPPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEAAEPP-RVVRPEPGA-RALEPPAEDRRDEVVLRQKPPTGR
KIQLTPARQMNLGLGDEPP-------EPEASGRGERLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPDRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLCYK
QILTKKGKKA---GS--GLRQWKRVYAALRARSLSL-SKERREPGPAA--GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSTA---
RGLRTQDQPAGSK--DDSAATSRTPWSINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVDDKDPQ-SVPNIEYLLPNIGRTVPPGDPGS--
D------STTCSSAKSKGSWAPKKE------LYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGVPAPGT-----------
--QGRPEGQLQGAAAPE---APGRLS--------------PPAAPEERP---------AA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVET--DTEGGAA
GA-GPGGRLTRRPSFSSHHLIP----CDTLARRRLSRSRPDGEG-AGAGAGRGTPRAAEL
------PGS-ASSSSQESLRPPAAAAA------AAVLGSRPSRIEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGSPEP------ASP
RAHSDNKDSGLSSLESTKARAPSSAASLPPAPGDPGA----------LQSQPLRRSATSR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MLVVLGKEGTWRGRHAPCPGLHAG
PPREHP---PRQLLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR-----------G----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSIMPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSCLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
ACPTRDLPGHQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RVVRPEPST-RAPEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIRREGWLYYK
QILTKKGKRR-----RGLRGVD-------------------------GEG-----LG-GN
QQDPERR--RAGP-------------------------------------LEPGDANPGP
G---CADPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAARGL
RT---QDLPAGSK--GRK-VVTETGWCVGAGSMGR---------GG---HVCVYWA----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPDFLKG--
-------LRSIMGR------------------------PRPLKGAAPAQ-----------
-------EPALCPAVMPRPFGPGFS----ILP-GEPLLSPFWPEDVLICFLPAHRRELRA
WIWASGSAEPAAGWGAG-VVSGQRA-----------------ARGXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXD
QGALQSQPSRRSA---ASRLHQ----CL--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------EDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLKAKHVPASSVVSSAMNSAPAVA
TSPSSPTFAFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGKILS
----------------------SLGTSEDT---RSKRHSTSDLSDVTFSD

PF00169 // ENSGT00920000148945_8_Domain_2 (1251, 1379)

VRKEGWLHYK
QILTKXGRKV-----GGGIRQWKRVFAVLRTHSLYL-CKDRREAVTCGPA-----PGEE-
---EQPISIRACLVDISYSETKRKHVFRLTTADFCEYLFQAEDREDMLAWIKVIRENS

ENSGT00920000148945_8_Linker_2_4 (1379, 1516)

KA
EGEVRATTHS-------------------------PPPQHSRGALALNNP----------
--------MVVFP--PDESSSQKAPWGINLMKKNKKSAPRAFGVRLEDCQPAPDNK----
-------------NV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1591)

PLIVEACCKVVEDRGLEYMGIYRVPGNNAVVSSLQEQLNKGATEI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTD-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------RDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_3 (471, 1338)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAAPARVSTRATMVPEPTSALPSDPR
SPAAWSDPGLRVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRMPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPPARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRASA-RTP
ACPTRDLPGPQ--------APPPPGLQGLDDLGY-VGYRSYSPSFQRRTGLLHALSFRDS
AFGGLPTFNLTQSPAPFPPEASEPP-RVVWPEPST-RSLEAPVEDRRDEVVLRQKPPTGR
KAQLTPARQINLGFGDQSP-------EPEASGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIRREGWLYYK
QILTKKGKVR-----------WQNPPASP---------------RPI---------LTAS
AARDICI--GSCLVDIS

PF15410 // ENSGT00920000148945_8_Domain_3 (1338, 1374)

YSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_3_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGFRTQDLPAGSK--DESAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PAHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------SATCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQ-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------ESPLTDLNFNEWKELGGGGPLEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASLPPTPGDPGA----------LQSQPPRRSATSR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MVPEPISALPPDPR
SPAAWSDPGSRVPSAT-RAHLDNSSLGMSQPRPSPGAFPHLPSESRTPRAF-----PEPG
SRVLPSRLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWASQRPSA-RTS
ACPSRDLT--Q--------APPPSGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQSPASFPPEASEPP-RVVRPDPST-RALEPPAEDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEA--RGERLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQEQPPGSK--EDSVAAPKTPWGINIIKKNKKAAPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSD-
S-------TTCSSAKSKGSWVPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKAAV-----GT-----------
--QEPPEGQLPGPAAEE---APGRLSPP--------------TAPDE---------RPAA
DTRSIVSGYSTLSTMDRSVCSGTG-----GRRAGAGDEADDERSELSHVETDTE-----G
GA-GPGGRLSRRPSFSSHHLMP----CDTLARRRLSRSRAEAEG-PGAGTARACPRGPEP
------PGS-ASSSSQESLRPPAAAPA------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPQES------VGV
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGA----------LQGLPQRRSAAAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSSG------RPLPWQGPRTLLLRKNLQDGFGFTLRHFI
VYPPESAVHCSLKEE

PF00595 // ENSGT00920000148945_8_Domain_0 (316, 471)

ENGGRGGRGGGG-RGG-----------------------------
-----------------------------------------GGPSPRHRLEPMDTIFVKN
VKDGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIGLIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_0_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPARASAWATMVPEPVSALPTDPR
SPTAWSDPGACVPSAT-RAHLDNSLLGMSQPRPSPGAFPHLPSESRTPRAF-----PEPG
SRVLPSRLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWTPQRPSA-RTS
ACPSRDLSGPQ--------APPSSGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPSFNLAQSPAPFPPEASEPP-RVVRPEPST-RTLEPPAEDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEA--RGERPGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQDQPAGSK--EDSAAAPRTPWGINIIKKNKKAAPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSED--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTMPPSDPGSD-
S-------TTCSSAKSKGSLVSKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKAAA-----GT-----------
--QEPPEEQLPGPTAVE---APGRLSPP--------------TAPDE---------RPAA
DTRSIVSGYSTLSTMDRSVCSGTG-----GRRAGAGDEADDERSELSHVETDTE-----G
SA-GPGGRLARRPSFSSHHLMP----CDTLARRRLSRSRADGES-PGVGTARAGPRGPEP
------LGS-ASSSSQESLRPPAAASA------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGDAPEP------AGA
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGN----------LQGLPTRRSTAAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MNIGLGDGVP-------EPEVGARVEHPGRRVAPLATTEDSLASIPFIG--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------DTSLPLPWSLAT----------------AVS
TPPSSRCPL----LPPACSLRSIK--AGRRPSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDVAFSDVRREGWLSYK
QVLTRKGKDA-----AGGWRLGFAAAM--PAP----------------------------
----RPL---------------------------------GLRRGSRAGWAPGPRALTRR
LSLLPQDPGCANQALISKKLNDYRKVSHGSGPKADASPKVSRGLGGLKSEFLKQSAVRSL
RT----QEPAGSK--DDSVATPKTAWGINIIKKTKKASPRAFGVRLEECQPAAENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCHVVEARGLESTGIYRVPGNNAVVSSLQQQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTNDKYSDFIEANRIEDARERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEQNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EGKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPASDPGSA-
-------DLLEI------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSPG------RPPPWQGPRTLLLRKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGG---GP---------------------------------
--------------------------------------------SPRHRLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDVLELAIMPKDEDIL-Q
LAYSQDAYLKGNQPYSGEARSIPEPPPVCYPRKSYAPPARVSAWATMVPEPVSALPNDPR
SPAAWSDQGPRVPAAT-RAHPDNSCLGMSQPRPSPGAFPNLPSESRTPRAF-----PEPG
SRVPPSRRQCQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEDVTAHRPWPCST
SQDALSQL-GQEGWH-RARSDDYLGRATRSAEALGPGALVSPRLERCGWASQRPAA-RTS
ACPSRDLPGPQ--------AAPLSGLQGLDDVGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPSFSLAQTPAPFPPEASEPAARVVRPEPSP-RALEPPTEDHRDEVVLRQKPPTGR
KVQLTPARQANLGIGDETP-------EPEPSGRGPRLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDAEA-PSKRPSTSDLSDANFSDIRREGWLYYK
QILTKKGKVRR-------AEAWGSGPXXXXXXALALAEQERQEPGPAAT-EAATAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLSWIRAIRENSRA
E---GEDPGCANQALISKKLNEYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQELPAAGK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMKTLRKLIRDL
PAHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGS--
D------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAPE----------------
----RPEGPPPAAEAPR---PPQP--------------PRQRG-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
RLPNRVPSLRMLRSFFTDGXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXX
XXXXX

PF00169 // ENSGT00920000148945_8_Domain_2 (1266, 1379)

XXXXXXXXKAGSGLRQWKRVYAALRARSLSL-SKERREPGPTAAGAAAA--GASE
EAPPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENS

ENSGT00920000148945_8_Linker_2_4 (1379, 1516)

RA
E---GEDPGCANQALISKKLNEYRKVSHSSGPKADSSPKGSRGLGGLRSEFLKQSAAA-A
LGLRTQEPPAGGK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1670)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDRYNDFIEANRIEDARERMKTLRKLIRDL
PGHYYETLKFLVGHLKTMADHSEKNKMEP-RNLA-VFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHXXXXXXXX--XXXXXXTPVDDKEPQ-AVPNIEYLLPNIGRTVPPGDPGS--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------SLDDTGY-IGYRSYSPSFQRRTGLL-ALSFRDS
PFGGLPTFNLPQSSAPFT--VSEPL-RVTRPEPNT-QPPELPTEERREEVVLRQKPPTGR
KAQQPPPRQMNFGFGDETS-------EPESSGQGEHPSRKVAPLAAAEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLKAKHVPASAVVSSAMNSAPVMG
TSPSSPTFTFALGRHYSQDCXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXSLDSLGTSEDA---PSKRHSTSDLSDVTFSD

PF00169 // ENSGT00920000148945_8_Domain_2 (1251, 1379)

IRREGWLYFK
QILTKKGKKV-----GGGLRQWKRVYAALRAHSLSL-GKERREAGTAAG------AG-EE
ETAPVCI--SSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENS

ENSGT00920000148945_8_Linker_2_4 (1379, 1516)

RA
E---GEDPGCANQALISKKLNDYRKVSHISGPKADSSPKSSRGIAGLRSELLKQNAP---
RSPRTQDPPSGTK--DDSAATSRAPWGINIMKKNKKPSPRAFGVRLEECQPAADNQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1670)

PLIVSACCRMVEARGLESMGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDEXXXXXXXXXXXXXXXXXXXXXXXXXXXKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EEKGER-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MNLGFGDESP-------EPEP--RGERPGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVFR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDAEA-PSKRHSTSDLSDAAFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLCYK
QILTRKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGFANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQDQPAGSK--EDSAAAPKTPWGINIIKKNKKAAPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSA-
D-------LLEI------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QAEDREDMLAWIKVIRENSKA
E---GEDPGFASQALISKKLNDYRKVSP-AGAKPDSSPKGPRGLG-IRAEFLKQTGTSAP
RSPRQDVAVT--K--DEG-SSQKAPWGINIMKKNKKSAPRAFGVRLEDCQPAPDNK----
-------------NV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1617)

PLIVEACCKVVEDRGLEYMGIYRVPGNNAVVSSLQEQLNKGATEI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDASERMRTLRKLV---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------QSAGI
RA-WP---PCLPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPPAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
VCPTRDLPGRQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RAVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEASGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-S--------------------ED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLKTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--QERPQGPLPGAVAP--------------------------------------EERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GVA
GA-GPGGRLTRRPSFSSHHLMP----CDTLA----------------RG----GPRVPEP
------PGS-ASSSSQESLRPPAAA-----------LASRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASLPPAPGDQGA----------LQSQPSRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MLQGRGGALGRAK--------QLSTAVTPY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPTSPTFTFALSRHYSQDCSSIR--AGRRSSYLLAVTTERSKSCDDGLNTFRDEGRALR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDTAFSDIRREGWLSYK
QVLTKKGKKA-----GGGLRQWKRVYATLRARSLCX-XXXXXXXXXXXXXXXXXXXXXXX
AAAPVCI-----------------------------GSCLAEDRDDMLGWIRAIREKAGP
-----RDPGCANQALISKKLNNYRKVSHGSGPKAEASPKVSRGLGGLKPEFLRQSAARAL
RT---QEQPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------HV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVATCCRIVEARGLESTGIYRVPGNNAVVCSLQEQLNRGLGDI
NPQDERWQDLNVISSLLKSFFRKLPEPLFTNDKYNDFIEANRIEDARERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEQNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--QDKGERVSRGER-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSPG------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGG---GGGGGG-----------------------------
-----------------------------------------GPSPR

PF00595 // ENSGT00920000148945_8_Domain_1 (407, 471)

HHRLEPMDTIFVKN
VKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARVSTWATMVPEPLSALPSDPR
SPAAWSDPGPRVPSTT-RSHLDNSSSGMSQPRPSPGAFPRLPPEPRMPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEEVTAHHPWPCST
SQGALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRPSA-HTS
ACPPRDLPAPQ--------APPPPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPASFPPEASEPP-RVVRPEPGT-RALEPPTEDRRDEVVLRQKPPTGR
KVQLPPARQMNLGFGEESP-------EPETSGRVERLGKKMAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFREEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QVLTK---KGKKAGGG--LRQWKRVYAALRARSLSL-SKERREPGPAA-AGAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSAPKADSSPKISRGLGGLKSEFLKQSAA---
RGLRTQDQPAGNK--DDSAATPKTPWGINIIKKNKKAAPRAFGVRLEECQPAIENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGS--
A------DLLEI------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPE---PRPPQLPLGPRDGCSPR------RPFPWQGPRTLLLYKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRYRLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLRVPPAA-RAHLDNSSLGMSQPRPSPGAFPHLSSEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
ACPTRDLPGPQ--------APPPSGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPASFPPEASEPP-RVVRPEPST-RALEPPAEDRGDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEASGRGERLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQDLPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSD-
-------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGT-----------
--QERPQGPLPGAVAP---EAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GAA
GA-GPGGRLTRRPSFSSHHLMP----CDTLARRRLARGRPDG-EGAGRG----GPRAPEP
------PGS-ASSSSQESLRPPAAA-----------LASRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASQPPAPGDTGS----------LQSQPPRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSSG------RPLPWQGPRTLLLRKNLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGQSK---GE-EQG-----------------------------
-----------------------------------------WGPSPRHRLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKN
VKDGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIGLIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPTRASAWATMVPEPTSALPTDPR
SPAAWSDPGSRVPSAT-RAHLDNSLLGMSQPRPSPGAFPHLPSESRTPRAF-----PEPG
SRVLPSRLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWASQRPSA-RTS
ACPSRDLPGPQ--------APPQPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQAPAPFTPEASEPP-RVIRPEPST-RTLEPPAEDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------DPEA--RGERPGRKVTPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDVTFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLCYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAA-AAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQDQPAGSK--EDSAAAPKTPWGINIIKKNKKAAPRAFGIRLEDCQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSV-
L-------PYLHCLLAQGSWVPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKAAA-----GT-----------
--QEPPEEQLPDPAAVK---TPGPQSPA--------------TAPEE---------RPAA
DTRSIVSDYSTLSAMDRSV-----------------------------------------
----------------SHHLMP----CDTLARRRLSRSRADGES-PGAGPARAGPRGPEP
------PSS-ASSSSQESLRPPAAAPA------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRRSWRR---HTVVVQSPLTDLNFNEWKELGGGGAPEP------TGA
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGN----------LQGLPPRRSTAAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GLDDVGY-I-YRSYSPSFQR-TGLLHAL--LDS
PFGGLPTFNLAQSAAPFLPEASEPY-RVILLEPSA-RGLEPPTEDHREEVVLRQKPPTGR
KIQLPSARQMNLGFSDESP-------EPETSGRGERLGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPILG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDVTFSD

PF00169 // ENSGT00920000148945_8_Domain_2 (1251, 1379)

IRREGWLYYK
QVLTK---KGKKAGGG--LRQWKRVYAALRARSLLL-SKERREPGPAAA-GAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENS

ENSGT00920000148945_8_Linker_2_4 (1379, 1516)

RA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGFRTQDQPAGSK--DDSVAIPKSPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------LV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1671)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
SGHYYETLKFLVGHLKTIADHSE-NKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTMPPGDPGS--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------QSAG-
---ITAWPPCLPQLPLGPRDGCSPR------RPFPWQGPRTLLLHKSPQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGR----------G-----------------------------
-----------------------------------------GGPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPR
SPAAWSDPGLCVPLAA-RAHPDNSSLGMSQPRPSPGAFPHLASEPRTPRAF-----PEPG
SRVPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMAPRARSASQDRLEEVAAPRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRSSA-RTP
VCPTRDLPGRQ--------APPPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RAVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEANGRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLKTQDLPAGSK--GRKVV-TETGWCVGAGSMGRGGHVC-----VLG---CVYLC----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSG-
-------ER----RGLGGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPGAGATAPGA-----------
--QERPQGPLPGAVAPEAPEAPGRLSPP--------------AA---------PEERPAA
DTRSIVSGYSTLSTMDRSVCSGAS-----GRRAGAGDEADDERSELSHVETDTE---GVA
GA-GPGGRLTRRPSFSSHHLMP----CDTLARRRLARGRPD-GEGASRG----GPRVPEP
------PGS-ASSSSQESLRPPAAA-----------LASRPSRMEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------AGA
RAHSDNKDSGLSSLESTKARAPSSAASLPPAPGDQGA----------LQSQPSRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSSG------RPLPWPGPRTLLLRKSLQDGFGFTLRHFI
VYPPESAVHCILKEE

PF00595 // ENSGT00920000148945_8_Domain_0 (316, 471)

ENGGRGGRGGGGGGGG-----------------------------
-----------------------------------------GGPSPRHRLEPMDTIFVKN
VKDGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIGLIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_0_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPTRAPAWATMVPEPISALPPDPR
SPAAWSDPGSRVPSAT-RAHLDNSSLGMSQPRPSPGAFPHLPSESRTPRAF-----PEPG
SRVLPSKLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWASQRPSA-RTS
ACPSRDLP--Q--------APPPSGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQSPASFPPEASEPP-RVVRPDPST-RDLEPPAEDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGGESP-------EPEA--RGERPGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
LLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQEQPPGSK--EDSVAAPKTPWGINIIKKNKKAAPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGEKTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSD-
S-------TTCSSAKSKGSWVPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKAAV-----GT-----------
--QEPPEGQLPGPAAEE---APGRLSPP--------------TAPDE---------RPAA
DTRSIVSGYSTLSTMDRSVCSGTG-----GRRAGAGDEADDERSELSHVETDTE-----G
GA-GPGGRLSRRPSFSSHHLMP----CDTLARRRLSRSRADAEG-PGAGTARAGPRGPEP
------PGS-ASSSSQESLRPPAAAPA------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPEP------VGV
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGS----------LQGLPPRRSAAAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GLDDLGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQSPASFPPEASEPP-RVVRPEPST-RALEPPVEDRRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPEASGRGERLGRKVTPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAVNSAPVLG
TSPSSPTFTFTLGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRIPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF00169 // ENSGT00920000148945_8_Domain_2 (1253, 1377)

REGWLYYK
QILTKKGKKA-----GSGLRQWKRVYAALRARSLSL-SKERREPGPAAAG-AAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRE

ENSGT00920000148945_8_Linker_2_4 (1377, 1516)

NSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQDLPAGSR--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGERTPVGDKEPQ-AVPNIEYLLPNIGRTVPPGDPGSA-
-------DL----LEI--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-VQLPPARQMNLGFGDESP-------EPEASGRGERLGKKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--ASRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIRREGWLHYK
QVLTKKGKXX-----XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX--X
---XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXDPGYANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAVRGL
WT---QDQSAGSK--DDNAAAHRTPWG

PF00620 // ENSGT00920000148945_8_Domain_4 (1468, 1671)

INIIKKNKKAPPRAFGVRLEECQPATENQXXXX
XXXXXXXXXXXXXX-----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXRWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDK--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDQGSG-
-------ESL--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MLPLGPRDGCSPG------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVHCSLKEEEN

PF00595 // ENSGT00920000148945_8_Domain_0 (318, 471)

GGRGG------GGG-----------------------------
-----------------------------------------GPSPRHHRLEPMDTIFVKN
VKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_0_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYHRKTYAPPARVSAWATMVPEPLSAPPSDPR
SPAAWSDPGPRVPSTT-RTHPDNPSLGMSQPRPSPGAFPR--------------------
--------------------------------------------DRLEDVTAHRPWPCST
SQGALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRPSA-RTS
ACSSRDLPAPQ--------AQPPPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQSQASFPPEASEPP-RVVRPEPST-RALEPPTEDRRDEVILRQKPPTGR
KVQLPPARQMNLGFGEESP-------EPETSGRVERLGKKVAPLATTEDSLASIPFIGEP
FFCSFVLQPPFLPPSHSFFSPLLFSSLFLLPPVFPPLSPSLPFVCPPTHPFLSLLLSCSL
SPPSLCLFVHFSLPSLHPFFILPFLCSFHSSFLPSTLHPTNTSVRHRARLCALLECVVPR
QGQSRGDAEGVLPGEQMLDKGEARVERPADSQVSGLTRGLCLTSISGMKQGLGGLEHWGC
GLGLEVRLGMGWAGSALSHLYPPLPLLADEPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFREESRALS
G--------HYLPSVVSLQSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF00169 // ENSGT00920000148945_8_Domain_2 (1253, 1377)

REGWLYYK
QVLTK---KGKKAGGG--LRQWKRVYAALRARSLSL-SKERREPGPAA-AGAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRE

ENSGT00920000148945_8_Linker_2_4 (1377, 1516)

NSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKDDSSPKISRGLGGLKSEFLKQSTA---
RGLRTQDQPAGSK--DDSAAPPKTPWGINIIKKNKKAAPRAFGVRLEECQPAIENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERLKRLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGDPGS--
D------STTCSSAKSKGSWAPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRRE-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPKDGCSPG------RPLHWQGPRTLLLRKSLQDGFGFTLRHFI
VYPPESAVHCNLKEEEYG

PF00595 // ENSGT00920000148945_8_Domain_0 (319, 471)

GRGGRGGTGG--------------------------------
-----------------------------------------GGASPRHRLEPMDTIFVKS
VRDGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQDS-DDTLELSIMPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPRLCYPRKTYALPARLSAWATMVPEPASALPSDPR
SPAAWSDPGP-------------LSSGMSQPRPSPGAFLHLPSEPRTPQAF-----PEPS
GRVLPSRLECQQALSHWLSKQVPRRAG-ESRCPAMPPRTRSASQDRLEDVTAHRVWPCST
SQDALSQL-GQESWH-QARSEDYLGRATRSAEALGPGALGSPRFERCGWASQRPTA-RTV
TCPARDLPGPQ--------APPVPGLQGLDDTGY-VGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQTPTPFPPEASEPP-KVSKPEPST-RALEPPTDDHREEVVLRQKPPTGR
KGPPGPTRQMNLGFGEETL-------EPEAGGRGERPGRRVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPTSPTFTFALSRHYSQDCSSIR--AGRRSSYLLAVTTERSKSCDDGLNSFRDEGRALR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDTAFSDIRREGWLSYK
QVLTKKGKKA-----GGGLRQWKRVYATLRARSLCL-SGR--------------------
--PPSCI--APCLVDISYSDTKRSTCSD-----------------------------SRA
E---GEDPGCANQALISKKLNNYRKVSHGSGPKAEASPKVSRGLGGLKPEFLRQSAARAL
RT---QEQPAGSK--DDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------HV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVATCCRIVEARGLESTGIYRVPGNNAVVCSLQEQLNRGLGDI
NPQDERWQDLNVISSLLKSFFRKLPEPLFTNDKYNDFIEANRIEDARERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEQNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--QDKGERTPVDDKEPQ-AVPNIEYLLPNIGRTGPPGDSGSG-
-------WWTGCGGALHAPWAPRKE------PCTREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EHEAAQAGVPGGPDPAD----------
----------------------------------------------------GSPTTLAP
DARYVVRP-----------------------SRARGEQARA-------------------
----TRARGGAGPSFSSHRLMA----GDTLARRRLSRGRANPED---------D------
--RAPAPGS-ASSSSQESLRPAAA---A------VALGARPSRLETLRLRLRGTADDM-A
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKEAGAQDT---------TGA
RAHSDNKDSGLSSLESTKARASSSAASL--PPGTWGPCRVWPR-----------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MNLGFSDESS-------EPEATGRGERLGKKVAPLANTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--TGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTK---KGKKAGSG--LRQWKRVYAALRARSLSL-SKERREPGPAV--GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAA---
RGLRTQEQPAGNK--DDTAAAPKTPWGINIIKKNKKVTPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTGPPGDPGSAD
L------LEI--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-AYSQDAYLKGNEPYSGGAQSIPEPPPICYPRKTYPFQSRPSPQDVSSGYSNSSCPGPIT
---TPLPERYCVPPAP-SM-PNHASYG--PPKHLPDHLPHGGLKDTSREGR-PSRDCIGA
APKSVSRLECQQALSNWISSQVPRRSSSEERHCAMPPRYRSVSQDRLGDAPASRGWPHSA
SQDTLTQSPAHDGWSYRARSENYLVKYGQSLEALEQSALVSPRYDRCMWPPDRFYR-HGD
PLPAH---VQK--------HPSQPNLQSIDDSGY-IGYRSYSPSFQRRTGLLHALSFRDA
TFGDLPTFNISQRPAKQENDTKPLE-RAS-PPQPT-EQLQPDSEERREEVVLRQKPPTGR
KMP-PPARQMNFVFPDDMKETDICDPPPPAQVAGKDNKRGVAPLATPEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLKAKHIPASSVVSSAMNSAPILS
TSPSSPTFTFAVNRHYSQDCSNIK--ASRRSSYLLAITTERSKSCDDGLNTFRDEGKFLR
RLPSRVPSLRMLRSFFTDGSLDSLGASEDT---RSKRHSTSDLSDVTFSDV

PF00169 // ENSGT00920000148945_8_Domain_2 (1252, 1378)

RKEGWLHYK
QILTKKGKKV-----GGGIRQWKRVFAVLRVHSLYL-CKDRREAVAIAPP-----PG-EE
EQPPISI--RACLVDISYSDTKRKHVFRLTTADFCECLFQAEDRDDMLAWIKVIRES

ENSGT00920000148945_8_Linker_2_4 (1378, 1516)

SKA
E---GEDPGFASQALINKKLNDYRKVRNAFGTKPDSSPKGPRTPG-LKSELQKQLGTGPP
RSPRQDAIALRGT--DDN-VHQKAPWSINIMKKNKKPVPRAFGVRLEDCQQAPDNK----
-------------KV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVEACCKVVEDKGLEYMGIYRVPGNNAVVSSLQDQLNKGSAEI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDASERMKTLRKLIRDL
PVHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDK--EDKGEKTPVDEQETQ-SVPNIEYLLPNIGRTAAPGDASD--
-------STNSGSAKSKASWGSRKEH------YHKEMLAISFISAVNRK-----------
-------RKKRREA-------KRFGSSTDDDS-EHELAARRDGEEEAVAE----EE----
-EKEAQGLRSSRGKG---PVPDGQS-----------------VPECSAKLETELEEKPAP
DARSIVSGYSTLSTIDRSLCSE--VQSV---AESRGEEADDERSEFSHVETDTENGFVPG
QG--SQN----RASFSSHHLMQ----CDTLARRKLSRPRRNSEASSKGSTE-AS------
--SSSLPG------SQESLQP----AGA------TEAHVRPSLTEQLRLRFRGSADDMLA
VRLRKPHSPETRRKKNSWRR---HTVVVPGSLKDLNYNEWKEQHVLGALEAACSLDSSSR
DALKDNKDSGLSSLESTKARPSSTTLGNVVAPSHQGSGEQQHHKGASEGCSAPRRTASLR
YHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------PSHVHRVG
GPRPSP---QVPQLPLGPRDGCSPA------RSLPWQGPRTLLLHKNLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGRGG--------------------------------------
------------------------------------------GPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKDDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPPARVSTWATMVPEPLSALPGDPR
SPAAWSDPGPRIPSTA-RSHPDHPSLGMSQPRPSPGAFPRHPSEPRTPRAF-----PEPG
SRAPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEEVTAHRPWPCST
SQGALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRFERCGWASQRPSA-RTP
ACAPRDLPGPQ--------APAPPGLQGLDDLGY-IGYRSYSPSFQRRTGLLQALSFRDS
PFGGLPTFNLAQSPAPFPPEASEPP-RVVRPEPST-RASEPPSEDRRDEVILRQKPPTGR
KVQLPPARQMNLGFGDESP-------EPEASGRGERPARKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QVLTKKGKKA-----GGGLRQWKRVYAALRARSLSL-SKERREPGPAAA-GAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSTA---
RGFRTQDQPAGSK--DDSVSTSKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERLKTLRKLIRDL
PGHYYETLKFLVSHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDS--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPGEPGRPR
PT---------DLSPAQGSWAPKKE------PYTREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKPEAGAPAPRA-----------
--QDRPEGQRPGAAAPE---APGR-LSP----R---------------------------
---------------RRRRSGRLR-----T--R-------ARSSRATPPSTWRRTRRAAR
GP-G-GR-PARRPSFSSHHLMPGDTLAR----RRLARSRADGEG-AGAAAGL--------
-----P-GSAS-SSSQESLRPPAAVA-----AAAAALGSRPSRLEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGPPES------AGP
RAHSDNKDSGLSSLESTKARAPSTAASLPPAPGDPGA----------PQSQPPRRSAASR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------PTSPSIDFQAKHVPASAVVSSAMNSA-VLS
TSPTSPTFTFALGRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNSFRDEGRVLR
RLPNRVPSLRMLRSFFTDGXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX--XXXXX-XX
XXXXXXX--XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLTSELLKQSAGRVL
RV---QDLPAGSK--DDSAAVPRTPWGINIIKKNKKVTPRAFGVRLEECQPAAENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1670)

PLIVAACCRIVETRGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEAHRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDE--EDKGER-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MEQQPLGPRDGCSPG------RPLPWQGPRTLLLHKSLQDGFGFTLRHFI
VYPPESAVPCSLKEEENGGRGG---GP---------------------------------
--------------------------------------------SPRHRLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKN
VKEDGPAHRAGLRTGDRLVKVNGESVVGKTYSQVIALIQNS-DDTLELSIMPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYALPARGPAWVAMVPEPLSALPGDPR
STAAWSDPGPCVPAAA-RAHLDTPSPGMSQPRPSPGAFPRLPSEPRTPRAF-----PEPG
SRAPPSRLECQQALSHWLSNQVPRRAG-ERRCPAMPPRARSASQDRLEDVTAHRPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRVARSAEALGPGALVSPRFERCGWAPQRASA-RTP
ACPPRDLPGPQ--------APPPPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQSPAQFPPEASEPP-RVARPEPSA---REPPAEDRRDQVVLRQKPPTGR
KAQPPPARQGNLGFGDEHP-------EPEASRRGERLGRKVAPLAATEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFAVSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRALR
RLPNRVPSLRMLRSFFTDGSLDSWGTSDDADA-PSKRHSTSDLSDTTFGDVRREGWLYYK
QILTK---KGKRAGPGEPRRGVVRVLSELRARSLSL-SKERREPGPAAA-GAAAAVAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADASPRGSRGLGGLKSEFLKQSTV---
RGLWTQDPSAGSK--EDSAAAPKTPWGINIIKKNKKVAPRAFGVRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVASLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDS--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTMPLGDPGSAT
D------STTCSSAKSKGSWTLKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDEDS-EQEAHKPGAGAPAPGT-----------
--QDRSEGQPQGAAGPE---APGR--------------LSPSAAPEERP------AADT-
--RSIVSGYSTLSTMDRSVCSGTG-----GRRAGAGDEADDERSELSHVET--DTEGGAA
GA-GPGDRPARRPSFSSHHLMP----CDTLARRRLSRSRPEGGL-AAARA-GGARS-PRS
------PAE-PAPAPLGRLPPP--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQVRARDQ-----G------QRPSWG-----------------------
--------HC------------RKQEG-AGS-----------------------------
-----------------------------------------PGPSPRHRLEPM

PF00595 // ENSGT00920000148945_8_Domain_1 (414, 471)

DTIFVKN
VKDGGPAHRAGLRTGDRLVKVNGESVVGKTYSQVIGLIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPTRASAWATMVPEPLSALPTDPR
SPAAWSDPGSRVPSAT-RAHLDNSLLGMSQPRPSPGAFPHFPSESRTPRAF-----PEPG
SRVLPSRLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWAPQRPSA-RTS
ACPSRDLPGPQ--------APPPSGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPSFNLAQSPAPFPPEASEPP-RVVRPEPTT-RALEPPVDDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------DPEA--RGERPGRKVTPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSASDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAA---
RGLRTQDQPAGSK--EDSAAAPKTPWGINIIKKNKKAAPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSD-
S-------TTCSSAKSKGSWVPKKE------PYAREMLAISFISAVNRK-----------
-------QKKRREA-------RGLGSSTDDDS-EQEAHKAAA-----GT-----------
--QEPSEEQLPDPAAVE---VPGRLSPP--------------TAPDE---------RPAA
DTRSIVSGYSTLSTMDRSVCSGTG-----GRRA-AGDEADDERSELSHVETDTE-----G
GA-GPGGRLSRRPSFSSHHLMP----CDTLARRRLSRSRADGES-PGAGTARAGPLGPEP
------PGS-ASSSSQESLRPPAAAPA------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGAPEP------TGA
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGN-------------LPPRRSTAAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSSG------RPLPWQGPRTLLLRKNLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGGQSK---GE-EQG-----------------------------
-----------------------------------------WGPSPRHRLEP

PF00595 // ENSGT00920000148945_8_Domain_1 (413, 471)

MDTIFVKN
VKDGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIGLIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPTRASAWATMVPEPTSALPTDPR
SPAAWSDPGSRVPSAT-RAHLDNSLLGMSQPRPSPGAFPHLPSESRTPRAF-----PEPG
SRVLPSRLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWASQRPSA-RTS
ACPSRDLPGPQ--------APPQPGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFNLAQAPAPFTPEASEPP-RVIRPEPST-RTLEPPAEDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------DPEA--RGERPGRKVTPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDVTFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLCYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAA-AAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQDQPAGSK--EDSAAAPKTPWGINIIKKNKKAAPRAFGIRLEDCQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSD-
S-------TTCSSAKSKGSWVPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKAAA-----GT-----------
--QEPPEEQLPDPAAVE---APGRLSPP--------------TAPEE---------RPAA
DTRSIVSGYSTLSTMDRSVCSGTG-----GRRA-AGDEADDERSELSHVETDTE-----G
GA-GPGGRLSRRPSFSSHHLMP----CDTLARRRLSRSRADGES-PGAGTARAGPRGPEP
------PSS-ASSSSQESLRPPAAAPA------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGAPEP------TGA
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGN----------LQGLPPRRSTAAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----VCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKISRGLGGLKSEFLKQSTA---
RGLRTQDPPAGNK--DDSAAPPKTPWGINIIKKNKKAAPRAFGVRLEECQPAIENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1671)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMADMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTMPPGDPGS--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------QLPLGSRDGCSSG------RPLPWQGPRTLLLHKNLQDGFGFTLRHFI
VYPPESAVHCSLKEEENGSRG---------------------------------------
-----------------------------------------GRPSPRHRLE

PF00595 // ENSGT00920000148945_8_Domain_1 (412, 471)

PMDTIFVKN
VKEGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIGLIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_1_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPTRAPAWATMVPEPISALPTDPR
SPAAWSDPGSRVTSAT-RAHLDNSSLGMSQPRPSPGAFPHLPSESRTPRAF-----LESG
SRVLPSRLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGALVSPRLERCGWASQRSSA-RTS
ACPSRDLPGPQ--------APPASGLQGLDDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQSPASFPPEASEPP-RVARPDPST-RALEPPAEDHRDEVVLRQKPPTGR
KVQLTPARQVNLGFGDESL-------EPEA--RGERPGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPNRVPSLRMLRSFFTDGSLDSWGTSEDAEA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQDQPAGSK--EDSVTTPKTPWGINIIKKNKKAAPRAFGIRLEDCQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSA-
D------STTCSSAKSKGSWVPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKAAV-----GT-----------
--QEPPEGQLPGPSAEE---APGRLSPS--------------TAPDE---------RPAA
DTRSIVSGYSTLSTMDRSVCSGTG-----GRRAGAGDEADDERSELSHVETDTE-----G
GA-GPGGRLARRPSFSSHHLMP----CDTLARRRLSRSRADA----------EGPRGPEP
------LGS-ASSSSQESLRPPAAAPV------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELDGGGPPES------AGV
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGA----------LQGLPARRSAAAR
LHQCL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNGVAFCLVGI
PPRPEP---RPPQLPLGPRDGCSSG------RPLPWPGPRTLLLRKSLQDGFGFTLRHFI
VYPPESAVHCILKEE

PF00595 // ENSGT00920000148945_8_Domain_0 (316, 471)

ENGGRGGRGGGG--GG-----------------------------
-----------------------------------------GGPSPRHRLEPMDTIFVKN
VKDGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIGLIQNS-DDTLELSI

ENSGT00920000148945_8_Linker_0_2 (471, 1253)

MPKDEDIL-Q
LAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYAPPTRAPAWATMVPEPISALPPDPR
SPAAWSDPGSRVPSAT-RAHLDNSSLGMSQPRPSPGAFPHLPSESRTPRAF-----PEPG
SRVLPSRLECQQALSHWLSNQIPRRAG-ERRCPAMPPRARSASQDRLEDVTTHHPWPCST
SQDALSQL-GQEGWH-RARSDDYLSRATRSAEALGPGSLVSPRLERCGWASQRPSA-RTS
ACPSRDLT--Q--------APPPSGLQGLGDIGY-IGYRSYSPSFQRRTGLLHALSFRDS
PFGGLPTFSLAQSPASFPPEASEPP-RVIRPDPST-RALEPPAEDHRDEVVLRQKPPTGR
KVQLTPARQMNLGFGDESP-------EPET--RGERPGRKVAPLATTEDSLASIPFID--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EPTSPSIDLQAKHVPASAVVSSAMNSAPVLG
TSPSSPTFTFALSRHYSQDCSSIK--AGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLR
RLPSRVPSLRVLRSFFTDGSLDSWGTSEDADA-PSKRHSTSDLSDATFSDIR

PF15410 // ENSGT00920000148945_8_Domain_2 (1253, 1374)

REGWLYYK
QILTKKGKKA-----GGGLRQWKRVYAVLRARSLSL-SKERREPGPAAA-GAAAAGAGED
EAAPVCI--GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRA

ENSGT00920000148945_8_Linker_2_4 (1374, 1516)

IRENSRA
E---GEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQTAV---
RGLRTQEQPPGSK--EDSVAAPKTPWGINIIKKNKKAAPRAFGIRLEECQPATENQ----
-------------RV

PF00620 // ENSGT00920000148945_8_Domain_4 (1516, 1667)

PLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDI
NLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDL
PGHYYETLKFLVGHLKTIADHSEKNKMEP-RNLALVFGPTLVRTSEDNMTDMVTHMPDRY
KIVETLIQHSDWFFSDD--EDKGERTPVDDKEPQ-SVPNIEYLLPNIGRTVPPSDPGSD-
S-------TTCSSAKSKGSWVPKKE------PYAREMLAISFISAVNRK-----------
-------RKKRREA-------RGLGSSTDDDS-EQEAHKAAV-----GT-----------
--QEPPEGQLPGSAAEE---AAGRLSPP--------------TAPDE---------RPAA
DTRSIVSGYSTLSTMDRSVCSGTG-----GRRAGAGDEADDERSELSHVETDTE-----G
GA-GPGGRLSRRPSFSSHHLMP----CDTLARRRLSRSRAEAEG-PGVGTARAGPRGPEP
------PGS-ASSSSQESLRPPAAAPA------L---GSRPSRVEALRLRLRGTADDMLA
VRLRRPLSPETRRRRSSWRR---HTVVVQSPLTDLNFNEWKELGGGGLPEP------VGV
RPHSDNKDSGLSSLESTKARASSAA-SL--PSGDLGA----------LQGLPPRRSAAAR
LHQCL