Query Results 

MPNQDEKGKKSEKKN-QGFSDFS-FRQCSDIKRLWSLLNVQASKQQLPALKVASLPRPQ-
--QKSS-KANGCKSQNLSQESSEAVELETFSVNYKNER--NFSQYPEHPLFLDIFTALIK
NRLACREWVERAQAIHLLRVLICLRLLMRDPFYQEVLHQINGV----EVLAQYMETTSDT
YLLYGEEHLNVDKLVNMTYIF-----QKLAA

PF00514 // ENSGT00910000144066_3_Domain_0 (212, 259)

VKGQRDWVISSGAHKT-------LVKLLA
ASDSNVLLGALLALTSLA

ENSGT00910000144066_3_Linker_0_1 (259, 572)

ESPECRQKISELSIVESLMMILREFDLLSKRLAADLLRLLCS
ETEVKEQVKIFDGVPTLLSLLHSD----------HLKLLWSVVWILVQICEDPEISVEIR
TWGGIKQLLHILKGEQYLISDRSSVGSLSSANASGRIRHLYLHEDLSPSEIQENK-----
LSLQA-ACCAALTELVLN-----DTNAHQIVQENGVYI---IGRLILPNKQHESI--RNK
ASILQ---CYAFRALRFLFSMERNRDLFK-RFFPPNLFEVFIDIGHYIRDIKAYEDLVLK
LNSVMEAELKQIADSIESINQNKTPTKFIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 870)

YAILDHLGSGAFGSVCKVKKRSGQNLFAM
KEINLHNPAFGKDKKDRDNSAESIVSELT--IIREQLCH-PNIVRYY---KTFLESDKLY
ILMELIEGAPLGEHFKSLKEKKQIFSEERIWNIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGER-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVVKSEPYGEKADVWAA
GCILYEMAALIPPFHSTNM----------LSLASKIVEAVYEPVPEGIYSEKVKHVITRC
LTSDA-E----LRPD-------IVEVCSLISDVMM-KYVDGLSSCQLTMERKLERERKRA
QKYLMETNKNAATCR-HQLLMLPHVTYTENNTSTRSSGVASYKSDFSESSIMTPGFIQ--
--ADN----QGMGHHVSFPLDSCCINNSEN-NIFIALDDELDPSDNFSCASSSYFKECTT
GLLKRSISASAGERHETSRDRSGSASSKSRPGVVQIDIL-YVIYPHLLPF------HFSL
VKC--PFLWQKHTYHKVVLKKQSYLSNGI-SAILKLTSAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHGNLKRRIIERYKKSLFSLQSNPCSLKAEIKKV------------
-------------------LQGSPEIIEPSFFTADCHGLLQSLGE-------KSGN--PN
CFDFEGGITYEQMQTIIEDVLEDSGYYSINSNRYYSYPWGVRNPSTGK------------

MPDQDKKVKATEKSTDKKQQGVT-IRDYSDLKRLLCLLNVQSSKQQLPAINFDSVQNSIM
KSEPAV-RTGGHRARGRWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVDRAPSLHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVAHG
YLGYGEAQHSVDKLVNMTYIF-----QKLAAVRDQREWVTTSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
ERQVREQVKLYEGVPVLLSLLHSD----------HLKLLWSVVWILVQICEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLD-----DSNAHQVVQENGIYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFKSRLFPTDLFETFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENVESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKRHHFAEERLWKIFIQLCLALRYLHKEKRIIHRDLTPNNI
MLGDK-DRVTVTDFGLAKQKQE-----SSRLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLDPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVITTISRC
LTPDA-E----TRPD-------IVEVSSMISDIMM-KYVDNLSTSQLALEKKLERERRRT
QRYFMEANRNAIICQ-QEPTLLSQETFEKASLSSSSSGAGSLKSELSEITDLPAEGFQ--
-APCVKD--EDRTCDGLLSDDNFNLENIEK-DLYSELDDELDVSDNFSSSGSSPLKESTF
STLKRSFSASGGERQSQTRDFTGGIGSRLRPALLPLDLL-LKVPPLLLSA------HVKE
VEAELVTGWQSHSLPTVILHSLKHHGSLVGIFLST-ASAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRIIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSLGGKSLSSNDPTGL--PS
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNYPTKR------------

MPDQDKKVKTTDKSTDRKQPGST-PRDYSDLKRLRCLLNVQSSKQQLPAINFDSVPNSMV
KSEAAI-KAGAPRVRGQWHESTEAVELENFSINYKTER--NFSKHPQHQLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILYNLGGI----ENLAQYMEMVAHE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAIKEQREWVTASGAHKT-------LVNLLG
ARDTSVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLFEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
TWGGIKQLLHLLRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSDNLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEAFIDIGHYVRDISAYEKVVLK
LNVLAEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 868)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGVPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVRDTISRC
LTPDA-D----ARPD-------IVEVCSMISDVMM-KYLDNLSTSQLALEKKLERERKRT
QRYFMEANRNAVTCH-PELALLSQEPFEKASLSSSSSGAASLKSELSESADLPSEGFQ--
-PPCGKE--EDRVCEEILSDDHFHLESIEK-DLYSELDDELDISDNFSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFIGGIGSRPRPA----------------------------
-------------------------------------SAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSEGNSLSLNDQTGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR------------

------------------MPDQD-KRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMM
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQVGWKN-----------IYYMEMVANE
YLSYGEEQHTVDKLVNMTYIF-----QKLAATKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILQEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGNLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---VAKLILPNKQKNA----EK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLAIKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVQVSSMISDVMM-KYLDNLSSSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSEISESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPGNLVLFHIFPPFISSALLA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMDTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFGQHSNPCNLKSEIKRY------------
------------------------EPIEPNFFTADYHLLHHSSSGNSLSPNDPTGL--PT
SFELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR------------

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--------------------MERNRHLFK-RLFPTDLFEVFIDVGHYVRDISSYEELVSK
LNSLLEDQLKKISENIESVNQHKAPTKFIGN

PF00069 // ENSGT00910000144066_3_Domain_2 (572, 634)

YAILDHLGSGAFGCVYKVRKDSGQNLVAM
KEVNLHNPAFGKDKKDRDSSIKNIVSELT--IIKEQVSD-FFS--Y--------------
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--MELIEGAPLGEHFSSLKEKHHHFT

PF01636 // ENSGT00910000144066_3_Domain_1 (687, 737)

EERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAV
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISGVMM-KYLDNLSKSQLSLEKKLERERRRT
QRYFMEANRNTITCH-HELTLLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DTYSEVDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPP-MLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHA-----------SAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKK-------------
-------------------------------------------------PNDPTGL--PT
SFELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPDQDKKVKPTEKSADKKQQGTT-SRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMI
KCETAI-KAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGI----EDLAQYMETVANE
YLGYAEEQHCVDKLVNMTNIF-----QKLAAVKDQREWVTASGAHKT-------LVNLLG
ARDTNVLLGTLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIQENT-----
VSLQA-ACCAALTELALN-----DANAHQVVQENGVYT---IAKLILPTKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEDLVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---RTFLENDRLY
IVMELIEGAPLAEHFSSLKEKQQHFSEERLWRIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKHE-----SSKLTSMVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVADTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSQETFEKASLSSSSSGAASLKSELSESAELPGEAFH--
TMQCGKE--EDRTCEEVLSEDNFHLESVEK-DLYSELDDELDILDNCSSSSSSPLKESTF
SILKRSFSASGRERHSQARDFIGGIGSRPRPASAG-------------------------
----------------------------------------IAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTSDYHLLHHSLSANNWSQSDPTGP--PS
SLELEEGLTYEQMQTVIEEVLEESGYYNFATNRCHSYPWGT-KNYPTKR-----------

MPDQDKKVKATEKSTDKKQQGVT-TRDYSDLKRLLCLLNVQSSKQQLPAINFDSAQNSMM
KSEPAI-RAGGHRARGRWHESTEAVELENFSINYKNER--NFSKHSQHKLFQEIFTALVK
NRLICREWVDRAPSLHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVAHG
YLGYGEAQHSVDKLVNMTYIF-----QKLAAVRDQREWVTTSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
ERQVREQVKLYEGVPVLLSLLHSD----------HLKLLWSVVWILVQICEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLD-----DSNAHQVVQENGIYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFKSRLFPTDLFETFIDIGHYVRDISAYEELVSK
LNLLVEDELKQVAENVESINQNKAPSKYIGNYAI

PF07714 // ENSGT00910000144066_3_Domain_1 (575, 868)

LDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKRHRFAEERLWKIFIQLCLALRYLHKEKRIIHRDLTPNNI
MLGDK-DRVTVTDFGLAKQKQE-----SSRLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLDPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVITTISRC
LTPDA-E----TRPD-------IVEVSSMISDIMM-KYVDNLSASQLALEKKLERERRRT
QRYFMEANRNAITCP-REPTLLSQETFEKASLSSSSSGAGSLKSELSEITDLPAEGFQ--
-APCGKD--EDRTCDGLLSDDNFNLENIEK-DIYSELDDELDILDNFSSSSSSPLKESTF
STLKRSFSASGGERQSQARDFTGGIGSRLRPGPG--------------------------
------------------------FSGLVDFFLPI-ASAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRIIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSLGGNSLSSNDPTGL--PS
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNR---------------------------

MPDQDKKVKTSEKSADKKQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNNMT
KSETAI-KAGGHRARGQWQESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTSLVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGI----EDLAQYMEIVANE
YLGYAEEQHCVDKLVNMTYIF-----QKLAAVKDQREWVTASGAHKT-------LVNLLG
ARDTNVLLGTLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEELSPGEIQENT-----
ASLQA-ACCAALTELALN-----DTNAHQVVQENGVYT---IAKLILPSKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEDLVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFNSLKEKQQHFTEERLWRIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----SSKLTSMVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTINRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDTLSTSQLALEKKLERERRRT
QRYFMEANRNALTCH-HELALLSQETFEKASLSSSSSGAASLKSELSESAELPGEGFQG-
ALQCGKE--EDRTCEEVLSEDNFHLESVEK-DVYSELDDELDILDNCSSSSSSPLKESTF
SILKRSFSASGRERHSQARDFIGGLGSRPRPASAG-------------------------
----------------------------------------IAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTSDYHLLHHSLAANNWSQSDPTGP--PT
NFELEEGLTYEQMQTVIEEVLEESGYYNFTTNRCHSYPWGT-KNYPTKR-----------

MPDQDKKVKITEKSADKKQQGIT-TRDYSDLIRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPTI-KAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEILHSLGGI----ENLAQYMEIVANE
YLSYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLC
ARDSNVLLGALLALASLAESPGCREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGVPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
XXXXX-XCCAALTELVLN-----DTNAHQVVQXXXXXX---XXXXXXXXXXXXX----XX
XXXXX---XXXXXXXXXXXXXXXXXXXXX-XLFPTDLFEIFIDIGHYVRDISAYEELVSR
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 731)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKVFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTV-------------------------------------------------
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MPDQDTKVKGTEKAAD-KQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNNTT
KSEPTI-RTGGHRARSQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGI----EDLAQYMEIVANE
YLGYAEEQHCVDKLVNMTYIF-----QKLAAVKEQREWVTASGAHKT-------LVNLLG
ARDTNVLLGTLLALASLAESSECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVIWILVQVCEDPETSLEIR
IWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIEENT-----
VSLQA-ACCAALTELALN-----DTNAHQVVQENGVYT---IAKLILPNKQSNA----AQ
TNLLQ---CYAFRTLRFLFSMERNRPLFK-RLFPTDLFETFIDIGHYVRDIGAYEDLVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFNSLKEKHHHFSEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----SSKLTSMVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTIRRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDRLSTSQLALERKLERERRRT
QRYFMEANRNAVTCH-RELALLSQETFEKASLSSSSSGAASLKSELSESTELPGEGCH--
-IPCGKE--DDRVCEEVLSEDNFQLESVEK-DLYSELDDDLDVLDNCSSSSSSPLKESTF
SIFKRSFSASGRERHSQARDFIAGVGSRPRPASAG-------------------------
----------------------------------------IAVSQRKVRQICDPIQQILI
QLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIELNFLTSDYHLPRHSQAANNWAPSDPTGS--PS
SFEVEEGVTYEQMQTVIEEVLEESGYYNFTTKRCHSFPWGTKS-YTAKR-----------

MPDQDEKVKTTEKSTDKKQQELT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPTI-RASGHRARGLWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLSYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVENELKQIAENIESINQNKAPWKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASNGKD--EDRACDEILSDDNFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFTRGTGSRARPALLPLDLL-LKVPPLMLRA------HVKE
LEAELVRGWQSHSLPAVILQNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVVERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFIADYHLLHHSSGRNSLSPNDPTGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR------------

MPDPDKKVKTTEKSTDKKQQGVA-SRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-KAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHVLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHNLGGI----ENLAQYMEMVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVKEQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELALN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEMFIDIGHYVRDISAYGELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGASLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----IRPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLERERRRT
QRYFMEANRNAVTCH-QELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-PPCGKD--EDRACDETLSDDAFHLEHIEK-DIYSELDDELDVSDNSSSSSSSPLKESTF
SILKRSFSASGGERQSQMRDYIGGIGSRPRPA----------------------------
-------------------------------------SAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLRHSLGGNSQSSNDLTGP--PT
SSDLEEGITYEQMQSVIEEVLEESGYYNFASNRYHSYPWGTKNHPTKR------------

-----------------------SPRDYSDLKRLRCLLNVQSSKQQLPAITFDSAPNSMT
KSEPAM-KAGGPRTRGQWHESTEAVELENFSINYKNER--NFSKHPQHELFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQVALTPLLL-----WSSLQYMEIVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKI-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHDYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQILHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENI-----
VSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYI---IAKLILPNKQKNA----AK
TTLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIGSINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 870)

YAILDRLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMASLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDIMM-KYLDNLSTSQLALEKKLDRERRRT
QRYFMEANRNAVTCH-HELALLSQETFEKASLSSSSSGAASLRSELSESADLPPEGFQ--
-APYGKD--EDRACDEILSDDNFNLESIEK-DIYSELDDELDISGNSSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFTGGIGSRPRPGNLVLANLS--------------------
---------------------------------ST-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRIIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADCHLLHHSSGGNGLSLNDPTGL--ST
SFDMEEGITYEQMQTVIEEVLEESGYYNFTSNR---------------------------

MPDQDRKVKTTDKSADKQQQGTT-TRDYSDLKRLVCLLNVQSSKQQLPAINFDSAQNSMT
RSEPTI-KVGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGT----ENLAQYMEIAANQ
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVRDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGVPVLLSLLHSD----------HLKLLWSVVWILVQLCEDPETSVEIR
VWGGIKQLLHLLRGDRNFVSDRSSLGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IATLILPNKQKNG----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDINAYGELVSK
LNSLVEDELKQIAENIESINQNKAPSKYIGNYAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEINLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRL

PF01163 // ENSGT00910000144066_3_Domain_1 (660, 748)

Y
IVMELIEGVPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLDPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDS-E----ARPD-------IIEVSSMVSDVMM-KYLDNLSTSQLALERKLERERRRT
QRYFMEANRNAVTCH-HELALLSHDTFEKASLSSSSSGAASLKSELSESVDLPSEGFH--
-APCGKD--EDRACEDILSDDTFNLETIEK-DIYSELDDELDVSDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTSTMGSRPRPALLPLDLL-LKVPPLTLRA------HVKD
LEAELVTGWQSHSLPAVILRSLKDHGPQMSSCLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLRHSSDGKSLSPNDPAGL--PS
SFDLEEGITYEEMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTK--R----------

MPDQDKKVKTTEKPTDKKHQES-TTRDYSDLKRLRCLLNVQSSRQQLPAINFDSAQNNMS
KSESTL-KAGSHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHILGGI----ENLAQYMEMVANE
YLGCAEEQHCVDKLVNMTYIF-----QKLAAVKDQREWVTASGAHKT-------LVNLLG
ARDTNVLLGTLLALASLAESPECREKISELNIVENLLMILRDYDLLSKRLTAELLRLLCA
EPQVKEQVKLFEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIQENT-----
VSLQA-ACCAALTELALN-----DTNAHQVVQENGVYT---IAKLILPNKQNNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNPLAM
KEVNLHNPAFGKDRKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----TSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFYSTNM----------LSLATKIVEAVYEPVPEGVYSEKVTNTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDTLSTSQLTLEKKLERERRRT
QRYFMEANRNAVTCH-HELAMLSHETFEKMSLSSSSSGGASLKSELLESADLPRD-IF--
-QPCGKE--EDRACEEVLSEENFHLESVEK-GTYSELDDELDILDNCSSSSSSPLKESTF
SILKRSFSASGRERQSQGRDFIGGIGR-PRPA----------------------------
-------------------------------------SAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPSLHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGGNSGSPSDPTGP--PS
CLDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNYQTKR------------

MPDQDRKEKTTEKSTDKQQQAIG-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
RSEVAI-KVGGQRARGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEMAANE
YLGYAEEQHSVDKLVNMTYIF-----QKLAAVRDQREWVTSSGAHKT-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLRLLWSVVWILVQVCEDPETSAALR
VWGGIKQLLHLLRGDRNFVSDRSSLGSLSSANAAGRIQQLHLSEDLSPREIQENI-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNQQKNG----AK
TNLLQ---XXXXXXXXXXXX-XXXXXXXXXXLFPTDLFEIFIDTGHYVRDISAYGDLVAK
LNSLAEDDLKQIAENVESINQNKVPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 731)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGVPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTV-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKAKTTEKSTEKKQQGVT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-KVGGHRTRGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLSYGEDQHGVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGVPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGIYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVDDELKQIAENIESINQNKAPLKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFIEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVQAVYEPVPEGTYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLERERKRT
QRYFMEANRNAVTCH-QELALLSHDTFEKASLSSSSSGGTSLKSELSESADLPPEGFQ--
-APCGKD--EDRACDEILSEETFNLENIDK-DMYSELDEELDISDNSSSSSSSPVKESTF
SILKRSFSASGGERQSQTRDFTGGIGSRPRPGNFVLAVTKSHMPP---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKLKTTEKLTDKKQQGIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFESAQNSMT
KSEMAI-KAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHNLGGI----ENLAQYMEIVTNE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVRDQREWVTTSRAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSDDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISVYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLRPPFYSTNM----------LSLATKIVEAVYEPLPEGIYSEKVTSTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDTLSTSQLALEKKLDRERRRT
QRYFMEANRNAVMCH-HELALLSHETFEKVSLSSSSSGTASLKSELSESAELAPEGFQ--
-APCGKD--EDRACDEILSEDNFNLEAIEK-DIYSELDDELDISDNSSSLSSSPLKDSTF
SILKRSFSASGGERQSQTREFIGGIGSRPRPALLPLDLL-LKVPSFMVRS------HVKD
LEAELVPGWQSHSLPTVILRNLKDHA-----------SAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGENSLSPNDPTGL--PP
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRRAENSFSSLKSTHCLHRMLGKMQLAKE

MPDQDKKVKTTEKSTDKKQQGIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KTEHAI-KVGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVHRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLGYGEEPHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISGLNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENLESINQNKAPSKYIGNYAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRL

PF01163 // ENSGT00910000144066_3_Domain_1 (660, 748)

Y
IVMELIEGVPLGEHFSSLKEKQHHFVEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLERERKRT
QRYFMEANRNAVTCH-HELALLCHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-VPGSKE--EDRACDEILSEENFNLENIEK-DMYSELDDELDISDNSSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFTGGFGSRPRPALLPLDLL-LKVPPLMLRA------HVKE
IEAELVTGWQSHSLPAVILRNLKDHGPQMSTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHRPSGGNSLSPDDPTGL--CS
SSDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKTHPTKR------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MERNRHIFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLKEDELKQIAESIESVNQNKAPTKHIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 760)

YAILEHLGSGAFGSVYKVRKHNGQNLLAL
KEVNLHNPVFGKDKKDRDSRVQNIVSELT--IIKEQLYH-PNVVRYY---RTFLENDRLY
IVMELIDGVPLGEHFHSLKKKQQQFTEERIWNIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVKITDFGLAKQKQE-----NSKLASVVGTILYSW------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MELIEGA

PF00069 // ENSGT00910000144066_3_Domain_1 (670, 866)

PLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSQEAFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-APCGKD--EDRACEEILPDDNFNLENIDK-DIYSELDDELDISDNSSISSSSPLKESTF
SILKRSFSASGGERQSQTRDFTGGIGSRPRPALLPLDLL-LKVPPLMLRA------QVKE
LETELVTGWQSHSLPAVILRNLKDHGSTY-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKLKTTEKPPDKKQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFESAQNSMT
KSETAI-KACGPRARGQWHESTEAVELENFSINYKNER--NFSRHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQKEKR----I----GVGDLYMEIVAIE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVKEQREWVTMSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAE--------SELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSIVWILVQVCEDPETSLEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLQLSEDLSPHEIQENT-----
VSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDIGAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGNYAILDHLGSGAFGCVYKVTWRLGSIVLDI
LEQ--------------------------------------------------N

PF00069 // ENSGT00910000144066_3_Domain_1 (655, 770)

TYDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSDCILSLVTSYIH
TGVLP--VRYQGPFT--PI----------TVFVLQIVEAVYEPVPEGIYSEKVASTISRC
LTPDA-E----ARPD-------IVEVSAMISEVMM-KYLDNLSTSQLALEKKLDRERRRT
QRYFMEANKNAVTCH-HDLALLSHETFEKVSLSSNSSGAASLKSELSESADLAPEGFQ--
-APCGKE--EDRACDEVLSEDNFNLETIEK-DIYSELDDELDISDNSSSLSSSPLKDSTF
SKLSLQAHHLWE-----SSALW--LGVRP--CAC--------------------------
------------------------PGAGLFFRCSA-ASAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGENSLSPNDPTGK--SH
ESG---------------------------------------------------------

MPDQDKKVKTTETSADKKQSGVT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEHAI-KAGGRRSRGQWQESTEAVELENFSVNYKNER--NFSRHPQHKLXXXXXXXXXX
XXXXXXEWVNRAPSIHFLRVLICLRLLMRDPCYQEILHNLGGI----ENLAQYMEIVADG
YLGYGEEQHNVDKLVNMTXXX-----XXXXXXXXXXXXXXXXXXXXT-------LVNLLG
ARDTNVLLGALLALTSLAESPECREKISELSIVENLLMILHEYDLLSKXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX-----
XXXXX-XXXXXXXXXXXX-----XXXXXXXXXXXXXXX---XXXXXXXXXXXXXX--XXX
XXXXX---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNSLMEDDLKQIAENIESINQNKAPTKYIGNYAILDHLGSGAFGCVYKXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX

PF07714 // ENSGT00910000144066_3_Domain_1 (637, 729)

LYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHRFTEERIWNIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTV-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKLKTTEKPTDKKQQGIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFESAQNSMT
KAEAAI-KAGRHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVDRAPSIHFLRVLICLRLLMRDPCYQEILHHLGGI----ENLAQYMDIVANE
YLGCGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPQCREKISELSIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DANAHQVVQENGVYT---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPVFGKDKKDRDSSVKNIVSELT--IIKEQVNA-FL-VSED---ILLNNYDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMAALRPPFYSTNM----------LSLATKIVEAVYEPVPEGTYSEKVTSTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLDRERRRT
QRYFSEANRNAVTCH-HELALLSHETFEKVSLSSNSSGAASLKSELSEGADLAPEGFQ--
-GPCGKD--EDRACDEMLSEDSFNLETVEK-DIYSELDDELDISDNSSSLSSSPLKDSTF
SILKRSFSASGGERQSQTREFTGGVGPRPRPGNLVSAIL---------------------
--------------------------------LPA-ASAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPSFFTADYHLLHRSSGENSLSPNDPTGP--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNR---------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------LSPTETVSPI

PF07714 // ENSGT00910000144066_3_Domain_1 (763, 868)

PEVVKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGVYPEKLTVIIKRC
LTPDA-E----ARPD-------IVEVSSMIADVMM-KYLDVLATSQLALEKKLERERRRT
QRYFMEANRNTATCQ-QQLAILAHEHFEKASLSSSSSGAASLKSEFSENADLPPEAFQ--
-PPYGKD--EERSCEDILSDDNSTVENINK-DVYSELDDELDISVNSSSSSSSPLKELTF
GMLRRSLSASGGERQ-QGRDFSGGTGSRPRPGNLQFSANNFKQPHFTIPSSLKRLAQVKK
MEASLLTGWQSHGFPAVSLCHPKDLDSSLVTMIYRVTSAGIAVSQRKVRQISDPIQQILT
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFGQHSNPCNLKSEIKKL------------
-------------------SQGSPEQIEPNFFTADGHLLLHSSGGNTLSHNVRKGL--PS
SFNLEEGITYEQMQTVIEEVLEESGYYNFTSSRYHSYPWGTKNLPTKR------------

MPDQDKKVKTTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHGLGGI----ENLAQYMEIVASE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RVFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 760)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEDRLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCVQHFSPRSPAPALAT---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

PF00069 // ENSGT00910000144066_3_Domain_1 (763, 866)

PEVLKSEPYGEKADIWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPIQEGIYSEKVTIIISRC
LTPDA-E----ARPD-------VVEVSAMISDVMM-KYLDGLASSQLALEKKLERERRRT
QRYFMEANRNAVTCH-HELAILSHESFEKASLSSSSSGGASLKSELSESADLPPESFQ--
-QPCGKD--EDRACDELLSDDHYNLENIDK-DIYSELDDELDISDASSNSSSSPLKESTF
GILKRSFSASGGERQSHGREYTGGIGSRPRPALLPLDLL-LKVPSLMFRA------HVKK
IEASLVTGWQSHSLPAVILRNLKDHG-----------STY--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MEKLGNE
IATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPVEWIAAASHALS--APA--EVRLTP
------------------------------------------------------------
----PGGCGFYDGLLILLLQLLTQPGKGSLIRDVASSEMWTILWH---------------
---RFSMA-------------------------------LRLPEEVSPQESQPSQSPEPD
WTLISPQGMAALLSLAVATFTQEPQLCLSHLSQRGSILMTTLKHLLSPSFLRQLGQAPHG
SGFLPVVVLSVCQLLCFPFALDVDADLLGG----------------VLADLVD-------
--SEVTARLLQVCCHHLPLTQVELPVSLLTHLALTDSTSLNQFVNTVAAS----------
--------------------PRTIISFLSVALLGDQPLLTSDILSLLAHTARVLSPSHLS
FIQELLAGSD--ESYR----------------------------------------PLRS
LLGHPENSVRARTYGLLGHLLQYSMAVRGALQSQAGLL

PF13646 // ENSGT00910000144066_3_Domain_1 (759, 867)

NLLLLGLRDKDPAVRRGASFAV
GNAAYQAGPLGPALAAAIPSVTQLLGDPQAGIRRNAASALGNLGPEGLGEELL-----QC
QVPQRLLEMACGDPQLNVKEAALIALRSLRQEPCIHQVLVSLGA---------------S
ERLAMLSLGNQLLPH-------------------SSPRPASA------------------
-KHCRKLI-------HLLRPTHST------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDK-QQEIT-IRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPSYQEILHSLGGI----ENLAQYMEIVANE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESQECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLCEGIPVLLSLLHSD----------HLKLLWSIVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRFSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
SNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLAEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNAAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAV
GCILYQMAALNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNTVTCH-HELAVLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENT---ETYSEVDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPHMLRA------HIKE
LEAELVTGWHSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEQIEPNFFTADYHLLHRSSGGNSLSPNDPAGL--PT
SFELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPDQDKKVKTTDKSADKKQQGIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQDSMT
KSEPAI-RVGEHRARGQWHESTEAVELEN-SINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQXXXXXXXXXXXXXXXXXXXX----XX
XXXXXXXXXXXXXXXXXXXIF-----QKLAAVKDQREWVTTSGAHKXXXXXXXXXXXXX-
------XXXXXXXXXXXXXXPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQFHLSEDLSPREIQENT-----
FSLQA-ACCAALTELALN-----DTNAHQVVQXXXXXX---XXXXXXXXXXXXX----XX
XXXXX---CYAFRALRFLFSMERNRPLFKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQXXXXXXX-XXX---XXXXXX

PF00069 // ENSGT00910000144066_3_Domain_1 (657, 729)

DRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQXXXALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTV-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKITEKSTDKKQQGIV-ARDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPTI-KVGGYRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQELLHNLGGI----GDLAQYMEIVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIPQLHLSDDLSPQEIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGNYAI

PF07714 // ENSGT00910000144066_3_Domain_1 (575, 730)

LDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTV-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHGLGGI----ENLAQYMEIVASE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RVFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEDRLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKLTDTISRC
LTPDA-E----ARPD-------IVQVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCHLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSSGNSLSPNDPTGL--PT
SFELEEGITYEQMQTLIEEVLEESGYYNFTSNRYRSYPWGTKNHPT--KR----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MEK

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 735)

YHVLEMIGEGSFGRVYKGRKKYTAQVVAL
KFI----PKLGRSEKE----LRNLQREIE--IM--RGLRHPNIVHML---DSFETDKEVV
VVTDYAEG----ELFQI-LEDDGKLPEDQVQAIAAQLVSALYYLHS-HRILHRDMKPQNI
LLAKG-GGIKLCDFG---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDKKQQELT-TRDYSDLKRLRCFLNVQSSKQQLPAINFDSAQNSMT
KSELTI-RAGGHRARGPWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLSYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLVLASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPVFK-RLFPSDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPWKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKITDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHDTFGKASLSSSSSGAASLRSELSESADLVPEGFQ--
-ASYGKD--EDRACDEILSDDTFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFTGGTGSRARPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVVERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGRNSLSPNDPTGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR------------

MPDQDKKVKPTEKSADKKQQGTT-SRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMI
KCETAI-KAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGI----EDLAQYMETVANE
YLGYAEEQHCVDKLVNMTNIF-----QKLAAVKDQREWVTASGAHKT-------LVNLLG
ARDTNVLLGTLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIQENT-----
VSLQA-ACCAALTELALN-----DANAHQVVQENGVYT---IAKLILPTKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEDLVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---RTFLENDRLY
IVMELIEGAPLAEHFSSLKEKQQHFSEERLWRIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKHE-----SSKLTSMVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVADTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSQETFEKASLSSSSSGAASLKSELSESAELPGEAFH--
TMQCGKE--EDRTCEEVLSEDNFHLESVEK-DLYSELDDELDILDNCSSSSSSPLKESTF
SILKRSFSASGRERHSQARDFIGGIGSRPRPASAG-------------------------
----------------------------------------IAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTSDYHLLHHSLSANNWSQSDPTGP--PS
SLELEEGLTYEQMQTVIEEVLEESGYYNFATNRCHSYPWGT-KNYPTKR-----------

MPDQDKKVKTTEKSTDK-QQEIT-IRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQRKLFQEIFTALVK
NRLISREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESQECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSIVWILVQVCEDPETSVEIR
IWGGIKQLLHILQGDRNFVSDHSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
SNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPLKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 761)

YAILDHLGSGAFGCVYKVRKHSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCVQHLYLRSPAPALAT---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQNTKAKSTEKTAD-KQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNNMT
KSEPTI-RTGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGI----EDLAQYMEIVANE
YLGYAEEQHCVDKLVNMTYIF-----QKLAAVKDQREWVTASGAHKT-------LVSLLG
ARDTTVLLGALLALASLAESSECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVIWILVQVCEDPETSVEIR
IWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIEENT-----
VSLQA-ACCAALTELALN-----DTNAHQVVQENGVYT---IAKLILPNKQSNA----AQ
TNLLQ---CYAFRTLRFLFSMERNRPLFK-RLFPTDLFETFIDIGHYVRDIGAYKDLVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFNSLKEKHHHFSEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----SSKLTSMVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTIRRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDRLSTSQLALERKLERERRRT
QRYFMEANRNAVTCH-HELALLSQETFEKASLSSSSSGAASLKSELSESAELPGEGCH--
-IPCGKE--EDRVCEEVLSEDNFQLESVEK-DLYSELDDELDVSDNCSSSSSSPLKESTF
SILKRSFSASGRERHSQARDFIAGLGSRPRPASAG-------------------------
----------------------------------------IAVSQRKVRQICDPIQQILI
QLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKLSNWLPMIGEGSR
APHQNFWFQAEAEIIYNLLSQGSPEPIELNFLTSDYHSLRHSRAANNWSPSDPTGS--PS
SFEVEEGVTYEQMQTVIEEVLEESGYYNFTTK----------------------------

MPDQDRKVKTTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-KVGGHRPRGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILYSLGGI----ENLAQYMEIVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVRDQREWVTTSGAHKT-------LVNLLS
ARDTNVLLGTLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANASGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELALN-----DTNAHQVVQENGIYT---IAKLILPNKQKNA----AK
SNLLQ---CYF-RTLXXXXXXXXXXXXXX-XLFPTDLFEMFIDIGHYVRDISAYEGLVSK
LNLLVEDELKQ-AENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 760)

YAIMDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDKKQQGIT-TRDYSDLKRLRCLLNVQSSKQQXXXXXXXXXXXXXX
XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEMVAHE
YLSYGEEQHSVDKLVNMTYIF-----QKLAAIKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQXXXXXX---XXXXXXXXXXXXX----XX
XXXXX---CYAFRALRFLFSMERNRPLFKXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXXXXXXXXXXXXXXNSIGN

PF00069 // ENSGT00910000144066_3_Domain_2 (572, 635)

YAILDHLGSGAFGCVYKVRKHSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQXXXXXXXXXXX---XXXXXXXXXX
XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTV-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSADRKQPGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDTAQNNMM
KCDFAI-KAGAHRSRGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFIALVR
NRLICSEWVNRAPSIHFLRVLICLRLLMRDPCYQVCWKKNLNISVLVWSFLQYMEIVANE
YLGYAEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTSSGAHKT-------LVNLLG
ARDTNVLLGALLVLASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
ESQVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
SSLQA-GNCVILLSFAI--------LCHMIDYENGIYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSQ
LNLLVEDELKQIAENIESINQKKAPLKYISD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPVFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDS-E----ARPD-------IVEVSSMISDIMM-KYLDSLSISQLVLEKKLERERRRT
QRCFMEANRNVITCH-HELALLSHEAFEKVSLSSSSSGAASLKSELSESADLSGEGFQ--
-ASCGKE--EDRACEDVLSEENFHLESAEK-DAYSEMEDELDILDNFSSSSSSPLKESTF
SILKRSFSASGGERQSQARDFIGGLGSRPRPGNLELTTMTSH------------------
--------------------------------MPS-SSAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFMADCHLLHHPLGGNSWSPSDPTGKAPPT
SLDLEEGITYEQMQTVIEEVLEESGYYNFTSTR---------------------------

MPDQDKKVKTTEKPAEKKQQGIT-TRDYSDLKRLRCLLNVQSSKQQXXXXXXXXXXXXXX
XXXXXX-XXXXXXXXXQWHESTEAVELENFSINYKNER--NFSKHPQHKLFEEIFTALVK
NRLRCREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKI-------LVNLLG
ARD-SVLLGALLALASLAESPECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQILHILQGDRSFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYI---IA-LILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFKX-XXXXDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKEIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 731)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSNVKNIVSEIT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGVPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTV-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVASE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSMEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVQVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCHLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSSGNSLSPSDLTGL--PT
SFELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPDQDKKVKTTEKSTDKKQQEIT-IRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQRKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESQECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSIVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDHSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKFILPNKQKNA----AK
SNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAV
GCILYQMATLSPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNTVTCH-HELAVLIHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DTYSEVDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPHMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHRSSGGNSLSPNDPTGL--PT
SIELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPDQDKKVKTTEKSTEKKQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAIHFDSTQNSMM
KSEPTI-RGGAHRVRGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFEEIFIALVK
NRLICREWVDRAPSLHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVAHG
YLGYGEAQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLS
ARDTSVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
ERQVKEQVKLYEGVPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAQQVVQENGVYT---IAKLILPNKQKNA----AN
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNVLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKLSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFAEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DRVTVTDFGLAKQKQE-----SSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAAYDPVPEGIYSEKVTTTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALERKLDRERRRT
QRYFMEANRNAVTCH-RELAMLPHETFEKASLSSSSSGAGSLKSELSESVELPPEAFQ--
-APCVKD--EDQACDGILSDDNFNLESVEK-DIYSELDDELDISDNSSSSSSSPLKESTF
STLKRSFSASGGERQSQIRDFAGGIGSRPRPA----------------------------
-------------------------------------SAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVVERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHRASGDHSLSPSDPTGL--PS
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR------------

MPDQDEKGKTTEKATEKIQQGIT-TRDYSDLKRLRCLLNVQSSKQQLPAIKFESAQHSMT
KSEPAI-KVGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKVFQEIFTALVK
NRLICREWINRAPSIHFLRVLICLRLLMRDPCYQEILHNLGGI----ENLAQYMEMVANE
YLGYGDEQHSVDKLVNMTXXX-----XXXXXXXXXXXXXXXXXXXXT-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
XXXXX-XCCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFETFIDIGHYVRDISAYEELVSK
LNSLVEEELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 760)

YAILDHLGSGAFGCVYKVRKCSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHRFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHGLGGI----ENLAQYMEIVASE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RVFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEDRLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKLTDTISRC
LTPDA-E----ARPD-------IVQVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENT---EIYSELDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCHLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSSGNSLSPNDPTGL--PT
SFELEEGITYEQMQTLIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPHQDKKLKSIEKATDKKPHGIS-SRDYSDLKRLQSLLNVLSSKQQLPAVGFQNGQSSIT
RYLQNV-KSNGQNPHGQWQESTEVVELENFSVTYKNER--NFSKHPRHKLFQEIFTALVK
NRFACREWVDQAPSIHFLRVLICLRLLIRDPRYQEMLHSLGGI----ENLAQYMETVANS
YLDYGEQQHDIDKLVNMTYIL-----QKIAAVKDQREWVIASGAHKT-------LVNLLS
ARDSNVLLGALLALISLAESPECREKISELTIVENLLVILHEYDLLSKRLTAELLRLLCA
ESQVKEQVKMYEGIPVLLSLLHSD----------HIKLLWSVVWILVQVCEDPETSAEIR
VWGGIKHLLHILQGERNLVSDRSSVGSLSSANAAGRIQHLHLSEDLSSDEIQENT-----
FSLQA-ACCAAITELVLN-----DTNAYQVVQANGIYT---IAKLILPNKERNA----EK
TNLLQ---CYAFRALRFLFSMERNRHIFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLKEDELKQIAESIESINQNKAPARQIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 870)

YAILEHLGSGAFGSVYKVRKRNGQNLLAM
KEVNLHNPAFGKDKKARDSSVKNIVSELT--IIKEQLYH-PNVVRYY---RTFLENDKLY
IVMELIDGVPLGEHFNSLKEKQQRFTEERIWHIFIQLCLALRYLHKEKRIVHRDLTPNNV
MLGDK-DKVTVTDFGLAKQKQE-----NSKLASVVGTILYSCPEVVKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVGAVYEPVPDGLYSEKVSLTIKRC
LTPDA-E----TRPD-------IVEVSSLLSDVMM-KYLDVLSTSHLMLEKKMERERRRT
QRYFMEANRNAVTCH-RQLSTLPQKHYEKLSLLSSTNGTPTCKTEFSENIYIPAESFQ--
-SACGKNEDEERTYEEILIENNSTLENTEK-GMFSELDDEPDVLDNSSSSSLSHLKESPF
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDRKVKTTEKSTDKKQQGITTTRDYSDLKRLRCLLNVQSSKQQLPAITFDSAQNSMT
KSEPAT-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILYSLDGI----ESLAQYMEIVATE
YLSYGEEQHSVGKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKRMMKPRNSLVNLLG
ARDTSVLLGALLALTSLAESPECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELMQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 870)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKTDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQLHFAEERLWKIFIQLCLALRYLHKEKRIIHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSSNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDSLSTSQLALEKKLERERRRT
QRYFMEANRNAVTCH-HELAPLSQETFEKASLSSSSSGAASLRSELSESADLPP-GLQ--
-APCGRE--EDRACDEILSDDTFNLENIEK-DIYSELDDDLDISDNSSSSSSSPLKESTF
STLKRSFSASGGERQSQMRDFTGGVVSRPRPALLPLDLL-LKVPPLMLRA------HIKE
VEAELVTGWQSHSLPTVILRNLKDHGPQMSTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSAGGNSLSPSEPSGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHCYPWGTKNHPTKR------------

MPDQDKKVKATEKSTDKKQQGVT-TRDYSDLKRLLCLLNVQSSKQQLPAINFDSAQNSMM
KSEPAI-RAGGHRARGRWHESTEAVELENFSINYKNER--NFSKHSQHKLFQEIFTALVK
NRLICREWVDRAPSLHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVAHG
YLGYGEAQHSVDKLVNMTYIF-----QKLAAVRDQREWVTTSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLTILHEYDLLSKRLTAELLRLLCA
ERQVREQVKLYEGVPVLLSLLHSD----------HLKLLWSVVWILVQICEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLD-----DSNAHQVVQENGIYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFETFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENVESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKRHHFAEERLWKIFTQLCLALRYLHKEKRIIHRDLTPNNI
MLGDK-DRVTVTDFGLAKQKQE-----SSRLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLDPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVITTISRC
LTPDA-E----TRPD-------IVEVSSMISDIMM-KYVDNLSASQLALEKKLERERRRT
QRYFMEANRNAITCQ-QEPTLLSQETFEKASLSSSSSGAGSLKSELSEITDLPAEGFQ--
-APCGKD--EDRTCDGLLSDDNFNLENIEK-DIYSELDDELDISDNFSSSSSSPLKESTF
STLKRSFSASGGERQSQARDFTGGIGSRLRPALLPLDLL-LKVPPLLLSA------HVKE
VEAELVTGWQSHSLPTVILHSLKDH-----------ASAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRIIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPSFFTADYHLLHHSLGGNSLSSNDPTGL--PS
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWRTKNYPTKR------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

PF00069 // ENSGT00910000144066_3_Domain_1 (763, 866)

PEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTIRRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDRLSTSQLALERKLERERRRT
QRYFMEANRNAVTCH-HELALLSQETFEKASLSSSSSGAASLKSELSESAELPGEGCH--
-IPCGKE--EDRVCEEVLSEDNFQLDSVEK-DLYSELDDELDVSDNCSSSSSSPLKESTF
SILKRSFSASGRERHSQARDFIAGLGSRPRPALLP-------------------------
----------------------------------------LHLLGKV-PHQCPGTT----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDK-KQGIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEHVI-KVGGHRTRGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVHRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLSYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENLESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGVPLGEHFSSLKEKQHHFIEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----TRPD-------IIEVSSMISDVMM-KYLDNLSTSQLALEKKLERERKRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-APCGKD--EDRACDEILSEENFNLENIEK-DMYSELDDELDISDNSSSSSSSPLKESTF
SILKRSFSASGGERQSHTRDFTGGIGSRPRPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHA-----------SAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTTDYHLLHHSSGGNSLSPDEPAGL--RT
SFDSEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR------------

MPDQDKKVKTTEKSTDKKQQGIT-IRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-KAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----GNLAQYMEIVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAIKDQREWITTSGAHKT-------LVNLLG
ARDTNVLLGSLLALTSLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
TWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPQEIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSQ
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKHSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHRFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LNPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLERERRRT
QRYFMEANRNTVTCH-HELVLLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-APGGKD--EDRACDEILSDDNFNLENIEK-DIYSELDDELDISDNSSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFTGGIGSRPRPALLPLDLL-LKAPPLMLRA------HVKE
IEAELVTGWQSHSLPAVILQNLKDHGPQMSTFLWR-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGGNNLFPNDLSGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------VSQYMETVGNG
YLGNGEEQHNVDKLVNMTYIF-----QKFSAVKNQREWVIASGAHKT-------LVNLLG
ARDSNVLLGALLALTSLAESPECREKISELSIVENLLVILHEYDLLSKRLTAELLRLLCA
ESQVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQICEDPEISVEIR
IWGGIKQLLHILQGDRNLVSDRSSIGSLSSANAAGRIQQLHLSEDLSPQEIQENT-----
FSLQA-ACCAAITELVLN-----DTNAHQVVQENGVYI---VANLILPNRKRNA----VK
ANLLQ---CYAFRALRFLFSMERNRHLFK-RLFPTDLFEIFIDIGHYVRNISAYEELVSK
LNSLQEDELKQIAESIESINQNKAPSKYIGNYAILDHLGSGAFGSVYKVRKHNGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---RTFLENDRL

PF01163 // ENSGT00910000144066_3_Domain_1 (660, 748)

Y
IVMELIEGAPLGEHFHSLKEKQQQFTEDRIWNIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVVKSEPYGEKADVWAA
GCILYQMATLKPPFYSTNM----------LSLATKIVEAMYEPVPEGIYSEKMSVTIKRC
LTPDA-E----TRPD-------IVEVSSMISDVMM-KYLDGLSTSQFALEKKLERERRRT
QRYFMEANRNAVMCH-QQLAILSHEHSEKSSLSSSSSGAASFKSEFSESTDIPTENFH--
-PTSGKD--EDRTCDEILTDDHYTLENFEK-DVFSELDDELDISDNSSSSSSSPLKESAF
GIIKRSFSA--SERQPQTRDYIGGLGSRPRPALLPLELL-LRVPTLMFRA------NVKK
IETSLVKGWQSYSLPAVVLRNLKDHGRLLGKWVWRKSSAGIAVSQRKVRQISDPIQQILI
QLHKIIYISQLPPALHCNLKRRVIERFKKSLFSQQSNPCNLKLEVKKL------------
-------------------LQGSHELIEPNIFTADCHLLLHSTGGNVLAPDDRIGF--PG
SFDMEEGMTYEQMESVIEEVLEESGYYNFTSNRYHYYPWGTKNHPTKR------------

MPDQDKKVKITEKSADKKQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAPNSMT
KSEAAI-KAGGHRARGHWHESTEAVELENFSINYKNER--NFSKHPQHELFQEIFTALVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGI----EDLAQYMEIVANE
YLGYAEEQHCVDKLVNMTYIF-----QKLAAVKEQREWVTASGAHKT-------LVNLLG
ARDTNVLLGTLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIQENT-----
VSLQA-ACCAALTELALN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AQ
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEDLVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKRQHFTEERLWRIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----SSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGVYSEKVTDTISSC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLERERRRT
QRYFMEANRNAVMCH-HELALLSQETFEKASLSSSSSGAASLKSELSESAELPGEGFHAA
AMQCGKE--EDRPCEEALSEDAFHLEGVEK-DVYSELDDELDILDNCSSSSSSPLKESTF
SILKRSFSASGRERHSQARDFIGGLGSRARPASAG-------------------------
----------------------------------------IAVSQRKVRQISDPIQQILL
QLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTSDYYLLRHSLAANNWSQSDPTGP--PS
SLELEEGFTYEQMQTVIEEVLEESGYYNFTTNRSHSYPWGTTKNYPAKR-----------

MPDQDKKLKTTEKPPDKKQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFESAQNSMT
KSETAI-KACGPRARGQWHESTEAVELENFSINYKNER--NFSRHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQVTCPRL----------GGYMEIVAIE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVKEQREWVTMSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSIVWILVQVCEDPETSLEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLQLSEDLSPHEIQENT-----
VSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDIGAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRTGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLRPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVASTISRC
LTPDA-E----ARPD-------IVEVSAMISEVMM-KYLDNLSTSQLALEKKLDRERRRT
QRYFMEANRNAVTCH-HDLALLSHETFEKVSLSSNSSGAASLKSELSESADLAPEGFQ--
-APCGKE--EDRACDEVLSEDNFNLETIEK-DIYSELDDELDISDNSSSLSSSPLKDSTF
SKLSLQAHHLWE-----SSALWL--GVR--PCACP-------------------------
-------------------------GAGLFFRCSA-ASAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGENSLSPNDPTGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYILHLTG---------------------------

MPDQDKKAKTTEKSTDKKQQGIT-TRDSSDLKRLWCLLNVQSSKQQLPAINFDSAQNSMT
KSEPTI-KAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFLEIFTALVK
NRLICREWVTRAPSIHFLRVLICLRLLMRDPCYQEILHRLGGI----ENLAQYMEVVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVRDQREWVTASGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKAQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPEASVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENI-----
FSLQA-ACCAALTELVLS-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----TK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFETFIDIGHYVRDISAYEGLVSK
LNLLVEDDLRQIAENIESVNQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGVPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSLPFFSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTIRRC
LTPDA-E----ARPD-------IVEVSSMISDIMM-KYLDNLSTSQLALEKKLERERRRT
QRYFMEANRNTVTCHHHELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFP--
-TPCNKE--EDRACDEILSDDAFNLENIEK-DIYSELDDELDISDNSSSFSSSPLKESTF
SILKRSFSASGGERQSQTRDFPGGIGSRPRPALLPLDLL-LQVPPPMLRA------HVKE
LEVELVTGWPSHSLPAVILRSLKDHGPQMSTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTTDYHLLRHSSGGNSLSPNDLTGL--PT
SSDLKEGITYEQMQTVIEEVLEESGYYNFTSN----------------------------

MPDQDKKVKTTEKSTDKKQQEIT-IRDYSDLKRLRCLLNVQSSKLQLPAINFNSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILRSLGGI----ENLAQYMEIVANE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRTSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKTA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHYHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKVDVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDHLSTSQLSLEKKLERERRRT
QRYFMEANRNTVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASCGKD--EDRACDEILSDDNFNLENTEK-DTYSEVDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSSGNSMSPNDPTGL--PT
SFELEEGITYEQMQIVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPDQDKKVKTTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQ------------------YMEIVASE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRGGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVLEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVQVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPLMLRV------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCRLKSEIKKL------------
-------------------SQGSPEPIEPNFCTVDYHLLHHSSSGNSLSPNDPTGL--PT
SFELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPDQDKKVKSTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVASE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVQVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCHLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSSGNSLSPNDPTGL--PT
SFELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPDQDKKVKTTEKSTDKKQQGII-TRDYSDLKRLLCLLNVQSSKQQLPAINFDSARSSMT
KSEPAI-RVGGHGARGQWHESTEAIELENFSINYKNER--NFSTHPQHKLFQEIFTALVK
NRLICREWVDRAPSLHFLRVLICLRLLVRDPRYQEILHSLGGI----ENLAQYMEIVAHG
YLGSGEAQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSRAHKT-------LVNLLS
ARDTNVLLGALLAVASLAESPECREKISELNIVENLLMILHEYDLLSKRLSAELLRLLCA
ERQVREQVKLYEGVPILLSLLHSD----------HLQLLWSVVWILVQICEDPEISVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGQIQQLHLSEDFSPREIQENT-----
FSLQA-XXXXXXXXXXXX-----XXXXXXXXXENGIYT---IAKLILRNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX-XXXXXXX---XXXXXX

PF07714 // ENSGT00910000144066_3_Domain_1 (657, 729)

DRLY
IVMELIEGAPLGEHFSSLKEKQHHFAEERLWKIFIQLCLALRYLHKEKRIIHRDLTPNNI
MLGDK-DRVTV-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDTKAKSTEKTAD-KQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNNMT
KSEPTI-RTGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGI----EDLAQYMEIVANE
YLGYAEEQHCVDKLVNMTYIF-----QKLAAVKDQREWVTASGAHKT-------LVSLLG
ARDTTVLLGALLALASLAESSECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCA
EPQIKEQVKLYEGIPILLSLLHSD----------HLKLLWSVIWILVQVCEDPETSVEIR
IWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIEENT-----
VSLQA-ACCAALTELALN-----DTNAHQVVQENGVYT---IAKLILPNKQSNA----AQ
TNLLQ---CYAFRTLRFLFSMERNRPLFK-RLFPTDLFETFIDIGHYVRDIGAYKDLVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGD

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAVLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFNSLKEKHHHFSEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----SSKLTSMVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLSPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTIRRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDRLSTSQLALERKLERERRRT
QRYFMEANRNAVTCH-HELALLSQETFEKASLSSSSSGAASLKSELSESAELPGEGCH--
-IPCGKE--EDRVCEEVLSEDNFQLESVEK-DLYSELDDELDVSDNCSSSSSSPLKESTF
SILKRSFSASGRERHSQARDFIAGLGSRPRPASAG-------------------------
----------------------------------------IAVSQRKVRQICDPIQQILI
QLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIELNFLTSDYHSLRHSRAANNWSPSDPTGS--PS
SFEVEEGVTYEQMQTVIEEVLEESGYYNFTTKRCHSFPWVTKS-YTAKR-----------

MPDQDKKLKTTEKLTDKKQQGIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFESAQNSMT
KSEMAI-KAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHNLGGI----ENLAQYMEIVTNE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVRDQREWVTTSRAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSDDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISVYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLRPPFYSTNM----------LSLATKIVEAVYEPLPEGIYSEKVTSTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDTLSTSQLALEKKLDRERRRT
QRYFMEANRNAVMCH-HELALLSHETFEKVSLSSSSSGTASLKSELSESAELAPEGFQ--
-APCGKD--EDRACDEILSEDNFNLEAIEK-DIYSELDDELDISDNSSSLSSSPLKDSTF
SILKRSFSASGGERQSQTREFIGGIGSRPRPALLPLDLL-LKVPSFMVRS------HVKD
LEAELVPGWQSHSLPTVILRNLKDHA-----------SAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGENSLSPNDPTGL--PP
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRRAENSFSSLKSTHCLHRMLGKMQLAKE

MPDHDKKLKTTEKPTDKKQQEI--TRDYSDLKRLRCLLNVQSSKQQLPAINFESAQNSMT
KSETAI-KAGGHRARGQWHESTEAVELENFSINYKNER--YFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHTLGGI----ENLAQYMEIVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNG----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFNSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLRLPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTSTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLALEKKLDRERRRT
QRYFMEANRNAVVGH-HELALLSHETFEKVSLSSNSSGAASLKSELSESTDLAPEGFQ--
-APCGKD--EDRACDEILSEDNFNLDTIEK-DIYSELDDELDISDNSSSLSSSPLKDSTF
SILKRSFSASGGERQSQTREFIGGIGSRPRPALLPLDLL-LKVPPFMVRS------HVKE
LKAELVTGWQSHSLPAVILRNLKDHA-----------SAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHAS-----------GL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKSHPSKR------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--

PF00069 // ENSGT00910000144066_3_Domain_1 (663, 852)

MELIDGVPLGEHFHSLKEKQQKFTEERIWNIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVKITDFGLAKQKQE-----NSKLASVVGTILYSCPEVVKNEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVGAVYEPVPDGLYSEKVSFTIKRK
YLQVKIH----ISID-------MYYIFINFYHIFINDLDNKLSTIAFGLSXKEKEKKNEA
EKFDPANNNNSVAYY-YELKVHSYNHYDKLRLQGSTTGTASCRSEFSENLGILAENCH--
-STCRKD--EKRTYEEILTEDNSSLENSEKADLFSELDDELDVLDNSSSSSSRHLKES--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFAEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSSSQLALEKKLERERRRT
QRYFMEANRNAVTCH-HELALLCQETFEKVSLSSSSSGAASLKSELSESADLPPDGFQ--
-APCGKD--EDRACDEILSDDNFNLENIDK-DIYSELDDELDISDNSSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFPGGLGSRPRPALLPLDLL-LKVPPLTLRA------HVKE
LEAELVTGWQSHSLPTGILRNLKDHGPQMSTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYVTQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLRHASGGNSLSPKDPTGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPSKR------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MEK

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 735)

YHVLEMIGEGSFGRVYKGRKKYSAQVVAL
KFI----PKMGRLEKE----LRNLQREIE--IM--QGLRHPNIVHML---DSFETDKEVV
VVTDYAEG----ELFQI-LEDDGKLPEDQVQAIAAQLVSALYYLHS-HRILHRDMKPQNI
LLAKD-GSIKLCDFG---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDTKVKSIEKATDKKQQGTT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQSNMS
KSDPTI-KTGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHQLFQEIFTALVR
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGI----EDLAQYMEIVANE
YLGYAEEQHCVDKLVNMTYIF-----QKLAAVKDQREWVTSSGAHKT-------LVNLLG
ARDTNVLLGTLLALASLAESPECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCA
EPPVKEQVKLYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIQENT-----
VSLQA-ACCAALTELALN-----DTNAHQVVQENGVYT---IAKLILPNKQSNA----AK
TNLLQ---CYAFRTLRFLFSMERNRPLFK-RLFPTDLFETFIDIGHYVRDIGAYADLVSQ
LNLLLEDELKQIAENIESINQKKAPLKYIGDY

PF00069 // ENSGT00910000144066_3_Domain_1 (573, 866)

ALLDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQQHFSEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----SSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFCSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTETIRRC
LTPDA-E----ARPD-------IVEVSSMISDIMM-KYLDSLSTSQLALERKLERERRRT
QRYFMEANRNAVMCH-HELSLLSQETFEKASLSSSSSGAASLKSELSESAELPGEGCH--
-IPCGKE--EDRGCEEELSEDNFQLESVEK-DLYSELDEELDVSDNCSSSSSSPLKESTF
SILKRSFSASGRERHSQARDFIGGLGSRPRPASAG-------------------------
----------------------------------------IAVSQRKVRQICDPIQQILI
QLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIRKL------------
-------------------SQGSPEPIEPNFLTSDYHLLRHSSTAKNWSPSDPTGP--SS
GLEVEEGITYEQMQTVIEEVLEESGYYNFTTNRCHSYPWGTKS-YTAKR-----------

MPDQDKKLKTTEKLTDKKQQGII-TRDYSDLKRLRCLLNVQSSKQQLPAINFESAQNSMT
KSETAI-KAGGHRARGQWRESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHNLGGI----ENLAQYMEIVTNE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVRDQREWVTTSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPHEIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDIRAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKCSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLRPPFYSTNM----------LSLATKIVEAVYEPLPEGIYSKKVTSTISRC
LTPDA-E----ARPD-------IVEVSSVISDIMM-KYLDNLSTSQLALEKKLDRERRRT
QRYFMEANRNAVMCH-HELALLSHEAFEKVSLSSSSSGAASLKSELSESAELAPESFQ--
-APCGKD--EDRACDEILSEDNFNLETVEK-DTYSELDDELDISDNSSSLSSSPLKDSTF
SILKRSFSASGGERQSQVREFIGGIGSRPRPA----------------------------
-------------------------------------SAGIAVSQRKVRQISDPIQQILI
QLHKVIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGENSLSPNDPPGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSTRYHSYPWGTKNHPTKR------------

MPDQDKKVKTTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLSYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILQEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLYSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVQVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMDTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQHSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSSGNSLSPNDPTGL--PT
SFELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPS--KR----------

MPDQDKKVKSTEKSSDKKQQGLT-TRDYSDLKRLRCLLNVQSSKQQXXXXXXXXXXXXXX
XXXXXX-XXXXHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHELFQEIFTALVK
NRLICREWVHRAPSIHFLRVLICLRLLMRDPCYQXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-----------XXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXTLVNLLS
ARDTNVLLGSLLALTSLAESPECREKISELNLVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENI-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQRNA----AK
TNLLQ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQXXXXXXRVRYY---KTFLEN

PF07714 // ENSGT00910000144066_3_Domain_1 (657, 749)

DRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSAEKQQQGVS-TRDYSDLKRLRCLLNVQSSKQQLPAIHFDSAQNSMT
KSEHAL-KAGGHRIRGHWQESTEAVELENFSVNYKNER--NFSQHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHNLGGI----ENLAQYMEIVADG
YLGYGEEQHNADKLVNMTYIF-----QKLSAVKDQREWVIASGAHKT-------LVNLLG
ARDTNVLLGALLALTSLAESPECREKISELTIVENLLMILHEYDLLSKRLTAELLRLLCA
ESQVKEQVKVYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
TWGGIKQLLHILQGDRNLVSDRSSIGSLSSANAAGRIQQLRLSEDLSPQEIQENT-----
FSLQS-ACCAALTELVLN-----DTNAHQVVQENGVYI---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNSLMEDDLKQIAENIESINQNKAPTKYIGNYAI

PF07714 // ENSGT00910000144066_3_Domain_1 (575, 732)

LDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERIWNIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVSKY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDKKQQEIT-IRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQRKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLGYGEEQHTVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESQECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSIVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDHSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKFILPNKQKNA----AK
SNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHQHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAV
GCILYQMATLSPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEANRNTVTCH-HELAVLIHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DTYSEVDDELDISGNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPHMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHRSSGGNSLSPNDPTGL--PT
SIELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MELIEGAPLGEHFHSLKEKQQHFS

PF01636 // ENSGT00910000144066_3_Domain_1 (687, 737)

EERIWNIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTITDFGLAKQKQE-----NSKLTSVVGTILYSCPEVVKSEPYGEKADVWAV
GCVLYQMATLNPPFYSTNM----------LSLATKIVEAAYEPVPDGIFSEKVSAIIKRC
LTPDA-E----NRPD-------IVEVSSMISDVMM-KYLDGLSTTQLVLERKLERERRRT
QRYFMEANRNAVTCH-HHLAVLSQEHYEKSSLSSSSSGAASLKSDFFENTDLPE-NFH--
-HSSGKD--VDKTCDEALSDDNCTTEKGNT-DVFSELDDELDVSDNSSSSSSSPLKDSAF
VVLECSAKA--S------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

MPDQDKKVKTTEKSTDK-KQGIA-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEHAI-KAGGHRSRGQWQESTEAVELENFSVNYKNER--NFSKHPQHKLFQEIFMALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHNLGGI----ENLAQYMEIVADG
YLGYGEEQHSVDKLVNMTYIF-----QKLSAVKDQREWVIASGAHKT-------LVNLLG
ARDTNVLLGALLALTSLAESPECREKISELTIVENLLMILHEYDLLSKRLTAELLRLLCA
ESQVKEQVKVYEGIPILLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
TWGGIKQLLHILQGDRNLVSDRSSIGSLSSANAAGRIQQLHLSEDLSPQEIQENT-----
FSLQS-ACCAALTELVLN-----DTNAHQVVQENGVYI---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISVYEELVSE
LNSLTEDDLKQISENIESINQNKAPTKYIGNYAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVKNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRL

PF01163 // ENSGT00910000144066_3_Domain_1 (660, 748)

Y
IVMELIEGAPLGEHFSSLKEKQHHFTEERIWNIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTIIYSCPEVLKSEPYGEKADIWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVQEGIYSEKVTVIISRC
LTPDA-E----ARPD-------VVEVSSMISDVMM-KYLDGLSTSQLALEKKLERERRRT
QRYFMEANRNAVTCH-HELAILSHENFEKASLSSSSSGGASLKSELSESADLPPESFQ--
-QPCGKD--EDRACDEILSDDNYNLENIEK-DIYSELDDELDISDNSSNSSSSPLKESTF
GILKRSFSASGGERQSHGREYSGGLGSKPRPALLPLDLL-LKVPSLMFRA------HVKK
IEASLVTGWQSHSLPAVILRNLKDHA-----------SAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADCHLLLHSSSGNTLSPNDRTGL--PN
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNYPSKR------------

MPDQDKKVKTTEKSTEKNQQELT-TRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMT
KSEPAI-RAGGHRARGPWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQ--------
-------------------IF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILQGDRNFVSDRSSIGSLSSANAAGRIQQLHLSDDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
THLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPWKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNVHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQRHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------VVEVSSMISDVMM-KYLDNLSTSQLSLEKKLERERRRT
QRYFMEASRNAVTCH-HELALLPHETFEKASLSSSSSGAASLKSELSESADLVPEGFQ--
-ASYSKG--EDRACDEILSDDNFNLESTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFTGGTGSRARPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPGLHHNLKRKVVERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSGRNSLSPNNPTGL--PI
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR------------

MPDQDKKVKTTEKSTDKKQQELT-TRDYSDLKRLRCLLNVQSSKQQLPAINFESAQNSMT
KSEPAI-RAGGHRARGPWHESTEAVELENFSINYKNER--NFSRHPQHKLFQEIFTALVK
NRLSCREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLGYGEEQHSVDKLVNMTYIF-----QKLAAVKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
EPQVKEQVKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPWKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKHSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNIVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKQHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NCKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLATKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVEVSSMISDVMM-KYLDNLSTSQLSLEKKLERERKRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEIMSDDNFNLENIEK-DIYSELDDELDISDNSSSSSSSPLKESTF
SILKRSFSASGGERQSQTRDFTGGTGSRARPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVVERFKKSLFSQQSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFIADYHLLHHSSGRNSLSPNDPTGL--PT
SFDLEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR------------

MPDQDKKVKTTEKSTDKKQQEIT-TRDYSDLKRLRCLLNVQSSKQQLPAINFNSAQNSMM
KSEPAI-RAGGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICREWVNRAPSMHFLRVLICLRLLMRDPCYQEILHSLGGI----ENLAQYMEIVANE
YLSYGEEQHTVDKLVNMTYIF-----QKLAATKDQREWVTTSGAHKT-------LVNLLG
ARDTNVLLGSLLALASLAESPECREKISELNIVENLLMILQEYDLLSKRLTAELLRLLCA
EPQVKEQMKLYEGIPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
IWGGIKQLLHILRGDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPREIQENT-----
FSLQA-ACCAALTELVLN-----DTNAHQVVQENGVYT---VAKLILPNKQKNA----EK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDISAYEELVSK
LNLLVEDELKQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 866)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDRLY
IVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DKVTVTDFGLAKQKQE-----NSKLTSVVGTILYSCPEVLKSEPYGEKADVWAA
GCILYQMATLNPPFYSTNM----------LSLAIKIVEAVYEPVPEGIYSEKVTDTISRC
LTPDA-E----ARPD-------IVQVSSMISDVMM-KYLDNLSSSQLSLEKKLERERRRT
QRYFMEANRNAVTCH-HELALLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQ--
-ASYGKD--EDRACDEILSDDNFNLENTEK-DIYSELDDELDISDNSSSSSSSPLKESTF
NILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLL-LKVPPLMLRA------HIKE
LEAELVTGWQSHSLPAVILRNLKDHGPQMDTFLWQ-ASAGIAVSQRKVRQISDPIQQILI
QLHKIIYITQLPPALHHNLKRRVIERFKKSLFGQHSNPCNLKSEIKKL------------
-------------------SQGSPEPIEPNFFTADYHLLHHSSSGNSLSPNDPTGL--PT
SFELEEGITYEQMQTVIEEVLEESGYYNFTSNRYHSYPWGTKNHPT--KR----------

MPDQDKKVKNTEKSADKK-QGIT-TRDXXXXXXXXXXXXXXXXXXXLPAINFESAQSSMT
KSEPAI-GVAGHRARGQWHESTEAVELENFSINYKNER--NFSKHPQHKLFQEIFTALVK
NRLICXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEILHSLGGI----ENLAQCMEMVAHG
YLSHGEAQHSVDKLVNMTYIF-----QKLAAVKDQ-RWVTTSGAHKT-------LVNLLS
ARDTNVLLGALLALASLAESPECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCA
ERQVKEQLKLYEGVPVLLSLLHSD----------HLKLLWSVVWILVQVCEDPETSVEIR
VWGGIKQLLHVLRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
XXXXX-XCCAALTELVLN-----DANAQQVVQENGVYT---IAKLILPNKQKNA----AK
TNLLQ---CYAFRALRFLFSMERNRPLFK-RLFPTDLFEIFIDIGHYVRDIAAYEELVSK
LNLLVEDELRQIAENIESINQNKAPSKYIGN

PF00069 // ENSGT00910000144066_3_Domain_1 (572, 731)

YAILDHLGSGAFGCVYKVRKRSGQNLLAM
KEVNLHNPAFGKDKKDRDSSVRNIVSELT--IIKEQLYH-PNVVRYY---KTFLENDSLY
IVMELIEGAPLGEHFSSLKEKQHHFSEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNI
MLGDK-DRVTV-------------------------------------------------
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