Query Results 

-------------------MAAAPSFPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIITANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAGGA-WGPPTPWVAIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

-------------------MAAAPSHPAGLPGSPGPGSPPP-PGGLDLQSP-P-----PL
-LP-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSSSSSS-SS--
SSFYTGRPIELDKMLMSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEAADYS
EADKSS-ISD---ELEDSGVIPGSHSENALHASEEEEGEGHKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIITANVTYFV
GETPGGAPGG--PS-G-QGTEAVRGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWDQFVAERH------GTPAE---
GDLGGACLPQDHEMQGLA---ERISIL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCMADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

-------------------MAAAPSFPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

-------------------MAAAPSHPAGLPGSPGPGSPPP-PGGLDLQSP-P-----PL
-LP-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSSSSSS-SS--
SSFYTGRPIELDKMLMSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEAADYS
EADKSS-ISD---ELEDSGVIPGSHSESALHASEEEEGEGHKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIITANVTYFV
GETPGGAPGG--PS-G-QGTEAVRGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWDQFVAERH------GTPAE---
GDLGGACLPQDHEMQGLA---ERISIL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGETLING----------------------------DVPMEEATDFS
EADKGT-LMD---ESEDAGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIITANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 916)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRH--------------------------------------
-LHFKNIVHC------------DLKPE---------------------------------
-----------NVLLASADP-----FP-----------QIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLPGS--GPPTD---
RDFGGAYPPQDHDMHGLT---ERISVL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTAEELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGTPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLP--GSGLPTD---
RDLGGARPPQDHDMQGLA---ERISVL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKGT-LMD---ESEDAGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIITANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPDEVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQVREACQLPAT------------------PRPL

PF00069 // ENSGT00910000144054_0_Domain_4 (828, 968)

QV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPATPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLPGS--GPPTD---
RDFAGAHPPQDHDMQGLT---ERISVL

-------------------MAAAPSHLSGLPGSPRPGSPLPA-GSLELQSPPL-----PL
-----------PAP--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTELLPRRPPSSSSSSSSS--
TSFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGETLING----------------------------DVPMEEATDFS
DSDKTALLMD---ESDDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCLTLFQNNTTNRYYKEIPLSEILSVEPAQNFSLVPPGTNPHCFEIITANATYFV
GETPGGAPGG--PS-G-QGAEAARGWEMAIRQALMPVILQDAPSAPGHVPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDISDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHLW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--SPGLPTH---
RELAGACLPQDHEMQGLA---ERISLL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---VPGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALINGGERLVGVLRRKGGGAGLGGGPSDASIPADVPMEEATDFS
EADKGT-LMD---ESEDAGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIITANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPATPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLPGS--GPPMD---
RDFSGAHPPQDHDMQGLT---ERISVL

---------------------AASSAPAGLPLSPGTGSPRGPE----PPQPPP-----L-
----LLL---APAP-GGVSF-------HIQIGLTREFVLLPAASDLAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSLWLGTSES-----------LPCTPDELSRSSTETFSRRLPSSSSSS--S--
SASYMGRPIELDKLLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 376)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLG

ENSGT00910000144054_0_Linker_2_3 (376, 507)

EALING----------------------------DVPMEEASDFG
DSDKGSMMD----ESDDSGFIPGSHAENALSAEEEEEGEAGKSQ----------------
--SSLGYIPLMRVVQSVRHTTRKSST

PF00169 // ENSGT00910000144054_0_Domain_3 (507, 635)

TLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCLTLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIVTANTIYFV
GETPILAPGG--PG-GGQAAETARGWETAIRQAL

ENSGT00910000144054_0_Linker_3_4 (635, 684)

MPVILQDAPSTPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQ

PF00069 // ENSGT00910000144054_0_Domain_4 (684, 968)

IFPDEVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHCW--LQDYQTWLDLRELEGKMGERHITHESDDARWEQFAAEHTLPEGGEPRDGIGGL
GRVEQPFSPQDHEVQGLA---ERVSVL

-------------------MAAAPSHSAGLPGSPGPGSPPPP-GGLELQSPPP-----L-
-LP-QIP---TPGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSSSSSS-SS--
SSFYTGRPIELDKMLMSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEAADYS
ESDKSS-LSD---DLDDSGVIPGSHSENVLHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWLVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVESAQNFSLVPPGTNPHCFEIVTANVIYFV
GETPGGAPGG--PS-G-QGTEAIRGWETAIRQALMPVILQDAPTAPGHTPHRRASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSRISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELERKMGERYITHESDDARWDQFVTEQH------GTSAE---
GDLSGARLPQDHEMQGLA---ERISIL

-------------------MAAAPSHAAGLPCSPRPGSPLSA-GGLELHSPPQ-----AL
VP----Q---APAP--GISF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELRSTRL-LLDA------HPSSLP--
PSFYTARPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DMPMEEASDFN
DSDKTALLMD---ESDDSGVIPGSHSENALHASEEEEGEEGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILSVEPSQNFSLVPPGTNPHCFEIITANATYFV
GETPGGAPGG--PS-G-QGAEAARGWEMAIRQALMPVILQDAPSTPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDISDQIQ--NAAFMYPANPWSLISTG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELERKMSERYITHESDDARWEQFVAEHPLP------------
-ELAGAHLPQDHEMQGLA---ERISVL

-------------------MAASPSHLSGLPGSPGPGSPPPP-GGLELQSPPP-----QL
--A-QVP---APSS--GVSF-------HIQIGLTREFVLLPTASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSVGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSVRLSTSES-----------LPCMADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 376)

HTFLIHS-YTRPTVCQACKKLLRGLFRQGLQCKDCKFN
CHKRCATRVPNDCLG

ENSGT00910000144054_0_Linker_2_3 (376, 507)

EALING----------------------------DVPMEEAADFS
EADKSS-LMD---ESDDSGVIPGSHSENALHASEEEEGEGGKAE----------------
--SSLGYIPLMRVVQSVRHTTRKSST

PF00169 // ENSGT00910000144054_0_Domain_3 (507, 635)

TLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANVTYFV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQAL

ENSGT00910000144054_0_Linker_3_4 (635, 684)

MPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQ

PF00069 // ENSGT00910000144054_0_Domain_4 (684, 968)

IFPDEVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLDCMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDIKDQIQ--NAAFMYPACPWSRISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GPGLPAD---
GDFGGALPPQDHEMQGLA---ERISVL

-------------------MAASPSHLAGLPGSPGPGSPPPP-CGLELQSPPP-----LL
--A-QVP---APSS--GVSF-------HIQIGLTREFVLLPTASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSVGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLSTSES-----------LPCMADELSRSTMELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGEALING----------------------------DVPMEEATDFS
EADKSS-LMD---ESDDSGVIPGSHSENALHASEEEEGEGGKAE----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 600)

REGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANVTYF

ENSGT00910000144054_0_Linker_3_4 (600, 688)

V
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSTPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLDCMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDIKDQIQ--NAAFMYPACPWSRISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GPGLPAD---
GDLGGALPPQDHEMQGLA---ERISVL

-------------------MAAAPSQPVALPGSPGPGSPPPLGG-FELLSPPP-------
---LQPP---GPPPGPGVSF-------HIQIGLTREFVLLPASSELAHVKQLACSIVDQK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DXXG-LNYHKRCAFSIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSVRLGTSES-----------LPYTNDELSRSTMELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 376)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALLNG----------------------------DVPMEEATDFA
EADKTALLD----EPDDTGVIPGSHAENALRASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSSKDT------------L-XXXXY
WRLDC-CITLFLNNTTNRYYWEIPLSEILAVEPAQNFSLVPPGTNPHCFEIITANATYFV
GETPGGAPGA--PS--GQGAEAARGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQ

PF00069 // ENSGT00910000144054_0_Domain_4 (684, 738)

IFPDEVLGSGQFGVVYGGKHR-KT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X--XXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXX
XXXXXXXXXXXXXX--XXXXXXXXXX--XXXXXXX-XXXXXXXXXXXXXXX----XXXXX
XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELERKVGKRYITHESDGARWEQFVLAEH------------TE
RELSGVLLPQDHEMQGLAECI---SVP

FPGFPQLDPGWALGPGPPPMAAAPSYSAGLPGSPGPGSPPPP-GVLELQSPPP-----LL
--P-QIP---APGP--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIHEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCMADELSRSTTDLLPRRPPSSSSSS--S--
VSSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGEALINGEDSLMAP------------------CLPDVPMEEATDFS
EADKSS-LID---ESDDSGVIPGSHSENALHASEEEEGEGGKAQRYPQNAPRSIGHSTEG
NIVSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 599)

REGWMVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIITANATY

ENSGT00910000144054_0_Linker_3_4 (599, 688)

FV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSQISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLH--DSMLPAS---
SEIVGVLPPQDHDMQGLA---ERISVL

-------------------MAAPPSHLAGLPGSPRPGSPLPA-GGLELQSPPL-----PL
-----------PAP--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTELLPRRPPSSSSSSSSS--
ASFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
DSDKTALLMD---ESDDSGVIPGSHSENALHATEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCLTLFQNNTTNRYYKEIPLSEILLVEPAQNFTLVPPGTNPHCFEIITANATYFV
GETPGGAPGG--PN-G-QGAEAARGWEMAIRQALMPVILQDAPTAPGHEPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF07714 // ENSGT00910000144054_0_Domain_4 (688, 778)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQ---------------------------------V--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDISDQIQ--NAAFMYPSSPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GPGLPTH---
GELARAPLPQDHEMQGLA---ERISLL

-------------------MAAAPSFPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCMADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTAIATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAGGA-WGPPTPWVAIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

-------------------MAAVPTHPAGLPGSPLPGSPPPTGPSLELQ--SPP------
--P---LQPQVPTPGPGVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
SLTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSMRLGTSES-----------LPCLADELSRSTTDLLPRRPPSSSSSSS----
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 376)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDYS
EADKSILMD----ESDDSGIIPGSHSENALHASEEEEGDGDKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTL-------------RKRHY
WRLDSKCITLFQNTTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX--------XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX--XXXXXXXXXXXXXXXXX-----------XIDLINNLLQVKMRKRYSVDKS
LSHSW--LQEYETWLDLRELEGKMGERYITHESDDARWEQLVTQHLQPG--PGLPFS---
AEHSGHLLPQEQEMQGLT---ERVSVL

-----------------------MAAPVGLPLSPGPGSPPPAHVGPELPPPLQQPQPQPP
PPPLLQP---VPGPPGGVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSGARKRRLS
STSLASGHSLRLGTSES-----------LPCTADELVRALGSRFFIPLVPLLSPQIXX--
XXXXXXXXXXXX------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

-------------------MATAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTAEELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGTPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLP--GSGLPTD---
RDLGGACPPQDHDMQGLA---ERISVL

-------------------MAATSSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_1 (180, 373)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-D----------------------------
------------------------------------------------------------
-------------------------------------------------------DCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTK-ESQLRNEVSILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAGGA-WGAPTPWAAIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESD--------------------------
---------------------------

-------------------MAAAPSFPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSVNLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPEHLAEYLSTFLTGPILALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

------------------SSWIPGIPAYKIPGIHGPGSPSPS-GGLELQSPPP-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASSHSVRLGTSES-----------LLSMTDELSRSTTELVPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGEALINGD----------------------------VPMEEATDFS
EADKSS-LTD---EPDDSGFIPGSHSENALHASEEEEGEGGKSE----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 599)

REGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANATY

ENSGT00910000144054_0_Linker_3_4 (599, 688)

FV
GETPGGAPGG--PS-G-QGAETARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLSSADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDIKDQIQ--NAAFMYPACPWSCISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWDQFVAEHPLP--GPGLPAD---
RVLGGTLPPPDHEMQGLA---ERISVL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGT--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCMADELSGSTTELLPRRPPSSSSSS--S--
VSSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESDDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLQHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSQISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHSW--LQEYQTWLDLRGLEGKMGERYITHESDDARWDQFLAERLLP--GSALPAD---
REIGGALPTQDHDMQGLA---ERISVL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSGARKRRLS
STSLASGHSLRLGTSES-----------LPCTADEL------------------------
--------------------------------------------------------CKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 599)

REGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGT-PHCFEIVTANATY

ENSGT00910000144054_0_Linker_3_4 (599, 688)

FV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQAMMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF07714 // ENSGT00910000144054_0_Domain_4 (688, 954)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELE-KMGERYITHESDDARWEQFVAEHPLP--GSGLPTD---
RDLGGARPPQDHDMQGLA---ERISVL

------------------MAAAP-SHPAGLPGSPGPGSPSPS-GGLELQSPPP-----LL
--P-QVL---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSVGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASSHSVRLGTSES-----------LLSMPDELSRSTTELIPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALINGD----------------------------VPMEEATDFS
EADKSS-LTD---EPDDSGFIPGSHSENALHASEEEEGEGGKSE----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNRDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANATYFV
GETPGGAPGG--PS-G-QGAETARGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLSSADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDIKDQIQ--NAAFMYPACPWSCISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDTRWEQFVAEHPLP--GPGLPAD---
RVLGGTLPPPDHEMQGLA---ERISVL

-------------------MAAAPSHPAGLPGSPGPGSPLPS-GGLELQSPPP-----LL
--P-HVP---APGS--GVSF-------HIQIGLTREFVLLPTASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCMADELSRSTTELIPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALINGGPSD-----------------------APVPPDEATDFS
EADKSS-LTD---ESDDSGFVPGSHSENVLHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANATYFV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVRHVPSWFGKVC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPACPWSRISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GPGLPAY---
GELGGTLPPPDHEMQGLA---ERISVL

-------------------MDAAPTQ----------QRRPTLSLLLCCFPPSSSFSSSPL
PPSVSSF---SSSSSSGVSF-------HLQIGLTRESVLLPAASEVAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPSSTNILQLVRAASDIQEGDLVEVVLSAAATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALNVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLANSQSLRLSTTDS-----------LPSTSDDLSRSSVELLPRRR---------V--
SSAYVGRPIELDKLFLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQFCKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGETLFNGS---------------------------DVTMEEPSDLS
EAEKNSLMD----ESDDSGIIPGSHSENDLRMGEDADDLS-------------------K
SRGSMGYIPLMRVVQSVRQTTRKSSTAL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 633)

KEGWVVHFSNKDT------------L-RKRHY
WRLDSKCLTLFQNNTSSRYYKEIPLSEILAIEAAQDFSLLPSGANPHCFEIITAKATYYV
GENG--VPSS--NQHGGDSLEQAKAWETAIRQALMPVVLQGAVPAQGEVPHRECLIE---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

---------MWGGVR--------IQAPRGLENSR-----YPVPGATDTPLPAS-----LA
PCSHQTR---AIAP-SRHTWAPASCLARAGLGSAGRKWGGPAGS------PEFPGETAGT
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELVRTWQGQP-RPPPR--RPPSSS--
SSFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DMPMEEASDFN
DSDKTALLMD---ESDDSGVIPGSHSENALHASEEEEGEEGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILSVEPSQNFSLVPPGTNPHCFEIITANATYFV
GETPGGAPGG--PS-G-QGAEAARGWEMAIRQALMPVILQDAPSTPGHAPWLQASLSLRE
NQCLA------------------------LSSLLSHFCHP

PF00069 // ENSGT00910000144054_0_Domain_4 (701, 968)

GKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDISDQIQ--NAAFMYPANPWSLISTG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELERKMSERYITHESDDARWEQFVAEHPLPG--PGLPTH---
VELAGAHLPQDHEMQGLA---ERISVL

-------------------MAAAPTHPAGLPGSPGPGSPPPS-TGLELQSPPA-----LL
--S-QGP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCMAEELTRSTTDLLGRRPPSSSSSS--S--
SSFYTGRPIELDKMLLTKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKTA-LLD---ETDDTGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFTLVPPGTNPHCFEIITANATYFV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHSGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSNISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELENKMGERYITHESEDARWDP------------EMPVD---
GELGGARLPQDHEMQGLA---ERISIL

-------------------SM---------------ASPPACAGPPALPSSPSTPGGCLA
TPELASLPPGSCAACQGVSF-------HIQIGLTREFVLLPAASDLAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDLSSANILQLVRVAGDIQEGDLVEVVLSGLASCKRESACKPH
HFQGLSLSL----SQFSSLYFELERPGLRALAGCGALNYLEFCSICVSSKVRGGLARLAA
SPSFSSPSVCP-HSSQSAAS--------M----ASTTRSCSSNMTCRLPTSCSWCVASEI
IASVRPSVLHLDRSLRRSVRPSVSYLDHSGGTRPTVCQFCKKLLKGLFRQGLQCKGSSSA
-VTGCNKRLG-ISLGKGLLRS----------------------------YVPMEDVSDLS
DADKNSLMD----ESDDSGIIPGSHSENELRGGDDPDDDASKSQ----------------
--GSMGYIPLMRVVQSVRHTNRKSSTALKEGWMVHYSSKDTL--------------RRYQ
WKPPLPRRALSQNNPSSRYYKEIPLSEILAVELAQNFTPVLPGANLHCFEIVTANATYYV
GENCAPAPCSASQQHSGVGLEVATAWENAIRQALMPVILQDAPSAQGQAPHRQASLRISV
SNSQIEENVVSI---S---------------SRSRSLCIER--KREQTGQEEYKRITQNQ
RSPGHKTSYIPQATESPQSLRHAGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPQPSAPNCPSFSSAPLGGRG---EPTSVRPSVRRAKLCLGR----------VPAAPGGG
SVRFARI

PF00069 // ENSGT00910000144054_0_Domain_4 (848, 962)

IGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIIWNSLSNPSPCNTP
SPPPPSVPPQGPAAQCPLSPT-----------ARCPSWTIDLINNLLQVKMRKRYSVDKS
PASPFAALQDYQTWLDLRELEAKMGERYITHESDDARWEQFAADHPLPYPAHLRAP----
---RGLSPEEEEGEQELQGLTERVSIL

-------------------MAAAPSHAAGVPGSPVPGSPPPP-GGLELQSPPP-----P-
-LP-QIP---TPGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSSSSSS-SS--
SSFYTGRPIELDKMLMSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDYS
EADKSS-LSD---DLDDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLVTRLGIAFANHL-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVESAQNFSLVPPGTNPHCFEIITANVTYFV
GETPGGAPGG--PS-G-QGTEAVRGWETAIRQALMPVILQDAPSAPGHTPHRRASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSQISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWDQFVTERL------DTSAE---
GDLGCARLPQDHEMQGLA---ERISIL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGT--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTDLLPRRPPSSSSSS--S--
VSSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESDDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 908)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLQHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSQISAGGACWGQCVAGVELNF--YWLGQSCSKRCSLLKL
TPVLP--AQEYQTWLDLRELEGKMGERYITHESDDARWDQFVAEHPLP--GPALPAD---
REIGGALPTQDHDMQGLA---ERISVL

------------------------------------------------------------
-----------------------------------------------------------Q
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDS-RYCEN
KVNYYSYKGLAICSHKATSQVGLRRRGFSR-RGCG-LNYHKRCAFSIPNNCSGARKRRLS
STSLASGHSVRLGTSES-----------LPCLADELVRGWLMGQVG-GWGVTGPRHGG--
NALYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 376)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLG

ENSGT00910000144054_0_Linker_2_3 (376, 507)

EALING----------------------------DVPMEEATDYS
EADKSVLMD----ESDDSGVIPGSHSENALHASEEEEGEGGKAQRY--------------
----LRYIPLMRVVQSVRHTTRKSST

PF00169 // ENSGT00910000144054_0_Domain_3 (507, 635)

TLREGWVVHYSSKDT------------L-RKRHY
WRLDSKCITLFQNNTTNRYYKEIPLSEILTIEPAQNFSLVPPGTNPHCFEIVTANATYFV
GETPGGAPGG--PS-G-QGAEAARGWEMAIRQAL

ENSGT00910000144054_0_Linker_3_4 (635, 684)

MPIILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQ

PF00069 // ENSGT00910000144054_0_Domain_4 (684, 968)

IFPDEVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPPSPWSHISKG-----------AIDLINNLLQ-KMRKRYSVDK-
LSHSW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFITEHPLP--GPGLPFD---
AELGGALPLQEHEMQGLA---ERVSVL

------------------------------------------------------------
------------------------------------------------------------
-----XYGLYDKILRFKHGPASANLLQRVRSANDIQEGDLVEVVLSATATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALNVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSGARKRRLS
STSLVSNKNAMVYCSAFIIKVQTEPSPLPPAPPPPQTRSSTESFPRRP--------AS--
SSSYMGRPIELDKLLLSKVKVPHTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKGGRGR
RRRVVGGR-PLK------LEGQ--------------------------------------
----------------RSAISQGLR-EDGREGAAGFLGRGGWGERID-------------
----PGPPPLFSLP--------------------------VPRPFPLFPLPRIQ-RKRHY
WRLDCKCITLFQNNTANRYYREIPLSEILAVEPAQNFSLVPPGTNPHCFEIITANATYFV
GETPVTAPGG--PNPCGQGAETGRGWESAIRQALMPVILQDAPSAPGHVPHRQASVSISV
SNSQI--PQEQQ----DIATVYQIFPD

PF07714 // ENSGT00910000144054_0_Domain_4 (688, 957)

EVLGSGQFGVVYGVGPHQKTFINLAAVKVIDKL
RFPTKQESQLRNEVAILQNLRHQGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNI-HCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDISDQIQ--NAAFMYPSSPWRQISAE-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQDYQTWLDLRDLEGKMGERYITHESDDARWERFAEDYSLPYPSHL-------
---------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------LLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRPH
ALTVHSYRAPAFCDHCAEMLFGLVRQGLKC-DGEG-RRVWG-------------------
-----------------------------------------PGFGK----------AG--
AGVGLGSRSELDKMLMSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 372)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNXXXXXX-XNG----------------------------DVPMEEAADYS
EADKSSLSD----DLDDSGVIPGSHSENALHASEEEEGEGGKAQRYQGPFRRL-------
--------------------------------------------FPPSPLQASVSPSLRW
ADVNCKCITLFQNNTTNRYYKEIPLSEILAVESAQNFSLVPPGTNPHCFEIITANVTYFV
GETPGGAPGA--PS--GQGTEAVRGWETIPG-ELLAEIHQDCPSQP------QASLSISV
SNSQI--QENVV----TP----------------------E--DPRPSPGLL

PF00069 // ENSGT00910000144054_0_Domain_4 (713, 968)

SVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVR-------YLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAPFMSPASPWSHISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKM------------------------------------
---------------------------

-------------------MAAAPSHPAGLPGSPGPGPPPPP-GGLEFQSP-P-----PL
-LP-QIP---APGS--GISF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYSLYDKILLFKHDPTSVNLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSSSSSS-SS--
ASFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEASDFS
ESDKSS-LTD---ELDDTGIIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVQPAQDFTLVPPGTNPHCFEIITANATYFV
GESPGGAPGG--PS-G-QGTEAARGWETAIRQALMPVILQDAPSAPGHMPHRQASLSISV
SNSQI---QENM----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSQISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEEKMGERYITHESDDARWDQFVTERH------GIPTE---
GDLGSIRLPQDHEMQGLA---ERISIL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCMADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

-------------------MAAAPSHPAGLPGSPGPGSPPPS-GSLELQAPPP-----LL
S---HVP---APG--SGVSF-------HIQIGLTREFVLLPTASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-EGCG-LNYHKRCAFSIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSVRLGTSES-----------LLSMTDELSRSTTELIPRRPTSSSSS--SS--
VSSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 376)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLG

ENSGT00910000144054_0_Linker_2_4 (376, 541)

EALING----------------------------DVPMEEATDFS
EADKSSLMD----ESDDSGFVPGSHSENALHASEEEEGEGGKAQXXXXXXXXXXXXXXXX
XXX------------------------------XXXXXXXXXXXXXXXXXXXXX-RKRHY

PF00069 // ENSGT00910000144054_0_Domain_4 (541, 968)

WRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIVTANTTYFV
GETPGGAPGG--PS-G-QGAETARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---PENV----XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVXXXXXXXXXXXXCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDIKDQIQ--NAAFMYPACPWSCISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARW----------------------
---------------------------

-------------------SMAAPSHPTGLPGSPGPGSPPPS-GGLELQSPPP-----LL
--P-LVP---APGP--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPASANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGVVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTPDELSRSTTDLLPRRPPSSSSSS--S--
ASSYTGRPIELDKLLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGEALING----------------------------DVPMEEATDFS
DADKGV-LVD---EPEDSGVIPGSHSENALRASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 599)

REGWVVHYSSKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNLHCFEIITANATY

ENSGT00910000144054_0_Linker_3_4 (599, 688)

FV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF07714 // ENSGT00910000144054_0_Domain_4 (688, 900)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSRISTG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFLAERRR---LPGLPAE---
GELAGALPPQDHEMQGLAGLAERVSIL

-------------------MAAAPSHPAGLPGSPGPGSPPPP-GGLELQSPQP-----LL
--A-QAP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTELLPRRPPSSSSSS--S--
ASFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSS-LMD---EADDSGVIPGSHSENALHASEEEEGEGDKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVETAQNFSLVPPGTNPHCFEIVTANATYFV
GETPGGAPGG--PS-G-QSAEVARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAERLLP--GPGLPTD---
TELGGTRLPQDHEMQGLA---ERISVL

-------------------MAAAPSHPAGLPGFPGPGSPPPP-GGLDPQSPPP-----LL
S---------AVPG-PGVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSS------S--
ASFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLVHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCASRVPNE

ENSGT00910000144054_0_Linker_2_3 (373, 530)

CLGEALLNG----------------------------DVPMEEATDFS
EADKSALAEEPDDAGVDSGVVPGSHSESALQAGEEEEGEGGKAQSDSVF-----------
--------------PSVKWEERMSPRTCQAGTS----------FYHGSS

PF00169 // ENSGT00910000144054_0_Domain_3 (530, 633)

KNNER-EKRHY
WRLDCKCITLFQNDTTNRYYKEIPLSEILTVEPAQNFSFVPPGTNPHCFEIITANATYFV
GE----------PH-G-QGAETARGWETAIRQ

ENSGT00910000144054_0_Linker_3_4 (633, 688)

ALMPVILQDAASTPGHAPHRQASLSISV
SNSQI---QENV----DIAAVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-SRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSCISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHSW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEQP-------LPGP---
GELGSAWVPQDHEMQGLA---ERVSVL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MFLSPLLPSS-----PDDVLPDLSP-AGCG-LNYHKRCAFSIPNNCSGARKRRLS
STSLASGHSLRLGTSES-----------LPCTPDELSRSSTEAFSRRLPSSSSSS--S--
STSYMGRPIELDKLLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGEALLNG----------------------------DVPMEEASDFG
DSDKSSLMD----ECDDGGVIPGSHAENALRASEEEEGEAGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 600)

REGWVVHYSNKDT------------L-RKRHY
WRLDCKCLTLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIVTANTTYF

ENSGT00910000144054_0_Linker_3_4 (600, 688)

V
GETPVLAPGG--PG-GGQGAETARGWETAIRQALMPVILQDAPSTPGHAPHRQASVSISV
SNSQI---QENV----DIATVYQIFPD

PF07714 // ENSGT00910000144054_0_Domain_4 (688, 823)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------SSW
GAPSWACSPDHE------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

-------------------MAAAPSHPAGLPGSSRPGSPLPA-GGLELHSPLQ-----PL
MP----Q---APAP--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTELLPRRPPSSSSS--SS--
SSFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEASDFN
DSDKTALLMD---ESDDSGVIPGSHSENALHASE-EEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILSVELAQNFSLVPPGTNPHCFEIITANATYFV
GETPGGAPGG--PS-G-QGAEAARGWEMAIRQALMPVILQDAPSAPGHVPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDISDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHSW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFLAEHPLP--GPGLPIH---
GELAGARLPQDHEMQGLA---ERISVL

----------------------------------------XXXXXXXXXXPPP-------
-PP-QIP---ASGA--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 226)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAF

ENSGT00910000144054_0_Linker_0_2 (226, 323)

SIPXXXXXXXGAGAR
----ARGH-----ARMR-----------PFHLADRQSRSTTELLPRRPPSSSSS--SS--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 508)

CLGEALVNG----------------------------DVPMEEATDFS
EADKSA-LMD---ESDDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTT

PF00169 // ENSGT00910000144054_0_Domain_3 (508, 595)

LREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTA

ENSGT00910000144054_0_Linker_3_4 (595, 688)

NATYFV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSTPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLAKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAGGGWS------PPIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GPGLPAA---
GELSGARPPQDHDMQGLA---ERISVL

----------------PPTHMTAPTHPSGLPGCPRPGSPPPTGPNSELQSPPPP------
--L---LLPQVAAPGPGVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSVRLGTSES-----------LPCMADELCRSTTELFPRRPPSSSSSSS----
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 354)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKXXXXX
XXXXXXXXXXXXXXXXXXXXX----------------------------XXXXXXXXXXX
XXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXX
XXXXXXXXXXXXXXPSGQGVEAARGWEMAIRQALMPVILQDTPSTPGHTPHXXXXXXXXX
XXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXXXXX

PF00069 // ENSGT00910000144054_0_Domain_4 (704, 968)

KHRKTGRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLITQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX--------XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPPSPWSHISKG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELERKMGERYITHESDDARWEQFVSVYPLPG--PGLPSD---
GELGGGLRPQDYEMQGLA---ERVSIL

-------------------MAAAPSHPAGLPGSPGPGSPPP-LGGLDLQSP-P-----PL
-LP-QIP---TPAS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSSSSSS-SS--
SSFYTGRPIELDKMLMSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEAADYS
EADKSS-VSD---DLDDSGVIPGSHSESALHASEEEEGEGDKAQ----------------
--SSQGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVESAQNFSLVPPGTNPHCFEIITANVTYFV
GETPGGVPGG--PS-G-QGTEAVRGWETAIRQALMPVILQDAPTAPGHTPHRRASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWDQFVTERQ------EMLAA---
GDLGGALLPQDHEMQGLA---ERISIL

-------------------MAAAPSFPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

-------------------MAAAPSHPAGLPGSPGPGSPSPS-GGLELQSPPP-----LT
AAP-QSP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSVGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASSHSVRLGTSES-----------LLSMPDELSRSTTELIPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGEALING----------------------------DVPMEEATDFS
EADKSS-LTD---EPDDSGFIPGSHSENALHASEEEEGEGGKSE----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 599)

REGWVVHYSNRDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANATY

ENSGT00910000144054_0_Linker_3_4 (599, 688)

FV
GETPGGAPGG--PS-G-QGAETARGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLSSADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDIKDQIQ--NAAFMYPACPWSCISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYIASR-QGARWDPPTPGPRDAGAGR--AHQ---
CPLRS-------RAPALA---AS----

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGXXXX-----------
--------------------------------------XXXAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTAEELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNTHCFEIVTANATYFV
GEMPGGTPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSTPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPDEVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLIT------------------------------------

PF00069 // ENSGT00910000144054_0_Domain_4 (828, 968)

QV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAGGA-WGPPTPWAAIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLP--GSGLPTD---
RDLGGARPPQDHDMQGLA---ERISVL

-------------------MAAAPSHPAGLPCSPGPGSPPP-PGGSDLQSL-P-----PL
-LP-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSSSSSS-SS--
SSFYTGRPIELDKMLMSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEAADYS
EADKSS-LSD---ELEDSGVIPGSHAENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFSLVPPGTNPHCFEIITANVTYFV
GETPGGAPGG--PS-G-QGTEAARGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWDQFVSERH------GTPAE---
GDLGGACLPQDHEMQGLA---ERISIL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------SRSTTDLLPRRPPSSSSSS--S--
ASSYTGRTIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 354)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------XXXXX------
----XXXXXXXXXXXXXXXXXXXXXXXXXXXXSEEEEGEGVKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVXXXXXXXXXXXXXXX------------
-XXXXXXXXXXXXXXXXXXXXEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANATYFV
GETPGGAPGG--PS--GQGAEAARGWENAIRQALMPVILQDAPSTPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQ

PF00069 // ENSGT00910000144054_0_Domain_4 (684, 927)

IFPDEVLGSGQFGVVYGXXXXXXXXXXXXXXXXX--X
XXXXXXXXXXXXXXXXXXSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSISGTFPFNED
EDINDQIQ--NAAFMYPASPWSRISAG---------------------------------
------------------------------------------------------------
---------------------------

-------------------MAAAPSHPAGLPGSPGPGSPPLP-GGLELQSPPP-----LP
--P-QAQ---TPVS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCMAEELSRSTAELLPRRPPSA---------
-SFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEAADFS
EADKST-FMD---ESDDSGIIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVEPAQNFSFVPPGTNPHCFEIVTANATYFV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGRAPHRQASLSISV
SNSEI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKS-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELERKMGERYITHESDDARWEQFVAERLGVESGLGLLAD---
ADLGGARLPQDHEMQGLA---ERISVL

-------------------MAAAPSFPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---VPGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

-------------------MAAPHSHLAGLPGSPGPGSPPPP-GGLELQSPPP-----QL
--A-QIP---APSS--GVSF-------HIQIGLTREFVLLPTASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSVGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLSTSES-----------LPCMADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMDEATDYS
EADKSS-LMD---ESDDSGVIPGSHSENALHASEEEEGEGGEAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANVTYFV
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSTPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLDCMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDIKDQIQ--NAAFMYPACPWSCISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GPGLPAE---
GDFGGALPPQDHEMQGLA---ERISVL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPP-----LL
--P-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKGS-LMD---EPEDAGVIPGSHSENALHVSEEEEGEGDKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIITANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSTPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 940)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQ---------------------------------------------
------------------------------------------------------------
---------------------------------------IDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLPGS--GPPTD---
RDFAGAHPPQDHDMQGLT---ERISVL

-------------------MAAAPSYPAGLPGSPGPGSTPPP-GGLELQSPPP-----LL
--P-QIP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTAEELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGTPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLP--GSGLPTD---
RDLGGARPPQDHDMQGLA---ERISVL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVETAQNFSLVPPGTNPHCFEIVTANATYFV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQVRPSCPGV---IVAHCGLKPL----ASAPRPLQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLPGS--GLPAD---
RDLGGAHPPQDHDMQGLA---ERISVL

-------------------MAAPPSHLAGLPGSPRPGSPLPA-GGLELQSPPL-----PL
-----------PAP--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQERSGVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTELLPRRPPSSSSSSSSS--
ASFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
DSDKTALLMD---ESDDSGVIPGSHSENALHATEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTWKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCLTLFQNNTTNRYYKEIPLSEILLVEPAQNFTLVPPGTNPHCFEIITANATYFV
GETPGGAPGG--PN-G-QGAEAARGWEMAIRQALMPVILQDAPTAPGHEPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDISDQIQ--NAAFMYPSSPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPL-------------
-----APLPQDHEMQGLA---ERISLL

-------------------MAAAPSHPAGLPGSPGPGAPPPPAGGSDLQSPPP-----PL
-LP-QLP---TPAS--GVSF-------HIQIGLTREFVLLPAASELAQVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTDLLPRRPPSSSSSS-SS--
SSFYTGRPIELDKMLMSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEAADYS
EADKSS-LSD---DLDDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHFSNKDP------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILAVESAQNFSLVPPGTNPHCFEIITANVTYFV
GETPGGAPGA--PS-G-QGTEAVRGWETAIRQALMPVILQDAPTAPGHEPHRRASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWDQFVTERQ------ETAAA---
GDLGGALLPQDHEMQGLA---ERISIL

-------------------MAAAPSYPAGLPGSPGPGSPPPP-GGLELQSPPA-----LL
--P-QVP---APGS--GVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGTSES-----------LPCTADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGEALING----------------------------DVPMEEATDFS
EADKSA-LMD---ESEDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 599)

REGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATY

ENSGT00910000144054_0_Linker_3_4 (599, 688)

FV
GEMPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF07714 // ENSGT00910000144054_0_Domain_4 (688, 954)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPASPWSHISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GSGLPTD---
RDLGGAHPPQDHDMQGLA---ERISVL

------------------------------------------------------------
-----------------------------------------------------------Q
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSGARKRRLS
STSLASGHSVRLGTSES-----------LPCTAEELNRSTTELLPRRPHSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVPHTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKEASPN
CVAKCGQRGGSQCLNPSMLKVR----------------------------ILVRSAGDIQ
EGDLVEVVL----SGERPWARPGA--ELRAEAGHLEEGEGRRAQKLAS------------
---SSQGPATMRLLYGVRSQESGSSTQVR-SWHSTALNS---------------PMAPHY
PWIGCKSITILAFFFLLRFKKIFPFSPQSPQVPSCVFSVVGPSGLEMRFEPMKASSVTVR
GKGRGAGPRG--RR--GQGAAWGRSWRWGGRRGLEPVGDLAPPEDEGHTPALALLCTQQV
RTVHSSMRICTSPVCSVCPAVRGIFSDVSVSKD------------LQLRGYRASKEIQSL
GYPYEKTETQRGKVRARDVAFEPWHTNLTSMLSQPLMAL--YQGLTIIMCPALISGARFC
L

PF00069 // ENSGT00910000144054_0_Domain_4 (782, 968)

SY---PVSLHLRPQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPACPWSCISVG-----------AIDLINNLLQVKMRKRYSVDKS
LSHSW--LQEYQTWLDLRELERKMGERYITHESDDTRWEQFVAEHPLPG--PGLPAD---
GELGGALPPQDHEMQGLA---ERISVL

-------------------MAAAPSHPAGLPGSPGPGSPPLP-GALDVQSPSA-----LL
TP--------APGP-GGVSF-------HIQIGLTREFVLLPAPPELAHVKQLACPSVDXX
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAADIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFNIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSVRLGSSES-----------LPCTSEELSRSTTDLLPRRPPSSSS----S--
ASFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 376)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEAFING----------------------------DVPMEEATDFS
EADKSA-LAE---EPDDSGVIPGSHSENALHTSEEEDGEEGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKRP--LEILTVEPAQNFSLVPPGTNPHCFEIITANATYFV
GETPGGAPG---PH-G-QGAESARGWETAIRQALMPVILQDAASAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQ

PF00069 // ENSGT00910000144054_0_Domain_4 (684, 968)

IFPDEVLGSGQFGVVYGGKH-RKT-SRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQ------------
-FGFRRIIGENPSRRLVVGTPAL-ATEVLLNQGY-RSLDMWSVGVIMYVSLSGTFPFNEV
EDINDQIQ--NAAFMYPGSPWSCISAG-----------AIDLINNLLQVKMRKRYSVDKS
LSHSW--LQEYQTWLDLRELETKMGERYITHESDDARWEQFMAEQPLPGTC----PA---
GELGRACLPQDHEMQGLA---ERVSVL

-------------------MAAAPSHPTGLPGSPGPGSPAPL-GSLELQSPLP-----LL
--P-QIP---APG--PGVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSVRLGTSDS-----------LPCTADELSRSTTELLPRRPQSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 376)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEATDFS
EADKSTLMD----ESDDSGVIPGSHSENALHAGEEEEAEGGKAP----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLHEGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX--XX-X-XXXETARGWT-AIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQ

PF00069 // ENSGT00910000144054_0_Domain_4 (684, 933)

IFPDEVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLELILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDINDQIQ--NAAFMYPACPWSRISAGXXXXXXXXXXXXX-----------XXXXXXXXX
XXXXX--XXEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GPGLPTD---
GELGGALPPQDHEMQGLA---ERISVL

-------------------MAASPSHLAGLPGSPGPGSPPPP-GGLELQSPPP-----QL
--A-QVP---APSS--GVSF-------HIQIGLTREFVLLPTASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSVGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLSTSES-----------LPCMADELSRSTTELLPRRPPSSSSSS--S--
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPND

ENSGT00910000144054_0_Linker_2_3 (373, 509)

CLGEALING----------------------------DVPMEEATDFS
EADKSS-LMD---ESDDSGIIPGSHSENALHASEEEEGEGGKAE----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTL

PF00169 // ENSGT00910000144054_0_Domain_3 (509, 600)

REGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILTVEPAQNFSLVPPGTNPHCFEIVTANVTYF

ENSGT00910000144054_0_Linker_3_4 (600, 688)

V
GETPGGAPGG--PS-G-QGAEAARGWETAIRQALMPVILQDAPSAPGHTPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 968)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLDCMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV--------KLC
DFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNED
EDIKDQIQ--NAAFMYPACPWSRISSG-----------AIDLINNLLQVKMRKRYSVDKS
LSHPW--LQEYQTWLDLRELEGKMGERYITHESDDARWEQFVAEHPLP--GPGLPAD---
GDFEGTLLPQDHEMQGLA---ERISVL

-------------------MAAAPSHPAGLPGSPGPGSPPPPGGF-ELQ--SPP------
--P---LQPQLPAPGPGVSF-------HIQIGLTREFVLLPAAFELAHVKQLACSIGDQK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 234)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNCSG

ENSGT00910000144054_0_Linker_0_2 (234, 323)

ARKRRLS
STSLASGHSVRLSISES-----------LPCTAEELSRSTMELLPRRPPSSSPSSS----
ASSYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 354)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKXXXXX
XXXXXXXXXXXXXXXXXXXXX----------------------------XXXXXXXXXXX
XXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------
--XSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTL-------------XXXXX
XXXXXXXXXXXXXXXXXXXXXEIPLSEILTVEPAQNFSLVSPGTNPH----CFEIITANT
TYFVGETPGGAPRGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHTPH---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

-------------------MAAAPSHPAGLPGSPRPGSPLPTSG-LELHLPPQ-----PL
----ALQ---APA--PGVSF-------HIQIGLTREFVLLPAASELAHVKQLACSIVDQK
FPECGFYGLYDKILLFKHDPTSANLLQLVRSAGDIQEGDLVEVVLSASATFEDF-QIRP

PF00130 // ENSGT00910000144054_0_Domain_0 (180, 232)

H
ALTVHSYRAPAFCDHCGEMLFGLVRQGLKC-DGCG-LNYHKRCAFSIPNNC

ENSGT00910000144054_0_Linker_0_2 (232, 323)

SGARKRRLS
STSLASGHSVRLGSSES-----------LPCTAEELSRSTTELLPRRPPSSSSSS-SS--
ASFYTGRPIELDKMLLSKVKVP

PF00130 // ENSGT00910000144054_0_Domain_2 (323, 373)

HTFLIHS-YTRPTVCQACKKLLKGLFRQGLQCKDCKFN
CHKRCATRVPNDCLGEALING----------------------------DVPMEEASDFN
DSDKTALLTD---ESDDSGVIPGSHSENALHASEEEEGEGGKAQ----------------
--SSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDT------------L-RKRHY
WRLDCKCITLFQNNTTNRYYKEIPLSEILSVEPAQNFSLVPPGTNPHCFEIITANAIYFV
GETPGGAPGG--PS-G---AEAARDWEMAIRQALMPVILQDAPSAPGHAPHRQASLSISV
SNSQI---QENV----DIATVYQIFPD

PF00069 // ENSGT00910000144054_0_Domain_4 (688, 822)

EVLGSGQFGVVYGGKH-RKT-GRDVAVKVIDKL
RFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGR
LPERLTKFLI---TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVLKTILHS----
--GLASISA-------WVSRPAV-----LLL-----TLFPWIEDTGIFLHITSMVWYEKD
GFVLFRLS--AST---QRSP----------------------------------------
------------------------------------------------------------
---------------------------