Query Results 

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHI-
DSGKST-T--TGHLIYKCG-SMNKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAECERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVREFEAGI---------SKNGQT-------------
-----------------REHVLLA-YMLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YKEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTGTPLSLPLQ-D
VYK----IVGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSIEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGC-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVI
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHINII-VIGHV-
ESGKST-T--TGHLIYKCG-GIDKR--TIEKLEKEA-AEMGKGSFKYAW---VL-----D
KL-KAECERGI--TT-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------PKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIIKE-VSTYTKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANV-PW
-FKGW-KVT-RKDGNASGTILL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGSI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRCGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTSHIACKF-AELKE
KIDRRSGK-KLEDGPQFLKS--GDAAIVDMVPGKPMCVE-----SFSNYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

---------------------------------KPPLNLR--ENGKGKDP

PF00009 // ENSGT00910000144046_0_Domain_0 (51, 404)

HMI-VIGQV-
DSGKST-T--TGHLIYKCG-WIDKR--TIETFEKEA-AELGKG-FKYAW---VL-----E
KL-Y--------------SLWK-----FETG--KYHVT--IFDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEASI---------SKNEQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEP------K
R----YKEIVKE-VSTYIKKI-GYNS--DTITFVPISGWNGDNMLQ-PS-----ANM-PW
-FKGW-KFT-CKDSNASGSTLL-----------EALDC---ILPPTHPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRMETGVLKPG--M-VVTYAPVSV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NESVKDVRRDNVAGDSKKD-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIVLNHP---GQISAGYAPVLD--------------------CHPAQIACKF-AELKE
KIDRHSGK-KLEDGPKFLKS--GIAAIVDMVPGKPMCVK-----TFSNYPLKGC-FAVLD
MRD--VA---------------------------------V--GVIKAVDKKVGGAGKVT
KSVQKAQKVK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINII-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AKMGKGSFKYAW---VL-----N
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-AVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNTLE-PS-----ANM-PW
-FKGR-KVT-HKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTGPVGRVETGVLKPG--M-VVTFAPVSV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-IK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

VGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAAFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MRKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 407)

KTNTCIF-VIGHV-
DSESTT-A--GLH--CKYR-GIDKR--TIEKFEKEA-AEMGKGSFKSAW---VL-----E
KL-KAGCEHGI--TI-DISVRK-----FETS--KYVS---IIDAP-----GHRDFMKNTI
A----G-TSQAD-AVFLV-VAAVG---EEAGI---------SKNGQT-------------
-----------------HEHALLP-YTLGVKELLVVIN--------KMESTKSPCS--QK
------EEIIKE--ITYIEKI-GYNP--DTVAFVPISG-NGDNMLE-PS-----ANM-PW
-FKGW-EVS-HKVGNATGTILL-----------EALDY---ILPRAGLTEKSLCLPLQ-D
VCK----IGGI-GIVPVGRVETGV-EPG--M-VVISAPVSV-TSEVKLVEMHHEAL----
----SE--ALPGDNIGFS-VK-----NVSVKDVRFGNVAGDSKND-L-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFS
AQVIILNHP---GQFSAGWAPVLD--------------------CHTVHIASMF-AKLKE
KIDRHSGK-NLDDGPKFFKC--GEAAIVDRVPSKPMYVE-----SFFDYP-LGR-FALCD
RRQT-VA---------------------------------V--GVIQAVEKKAAGAAQVS
ESAQKAK-----------------------------------------------------
----------------------------------------

------------------------------------------------------------
----------------------------------AD--EMGKGSF

PF00009 // ENSGT00910000144046_0_Domain_0 (106, 344)

KYAQ---VL-----D
KL---NTECELDITI-DISLGK-----LE----TYYLT--ITDAP-----GHRNFIKSML
P----G-TSQAQ-HAVLIA----VAGEYEAIA---------SKNGQS-------------
-----------------CEPALC--LCTGC-ELIVGVN--------KVDSTEPPYQ---E
R----YEKVIKE-VSTYIKKI-GCNP--KTRTFVPISGWKGDSLLE-PS-----ANM-PA
-FKGW-KLT-CKAGNSSGTMPV-----------EALGP---TLPPTYLTDAPC-------
---------G-----PS-----------------------------------GDSL----
----SE--ALPGDSVGFS-AK-----DVSVKDVHGGSVTGGSKNG-P-TM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 658)

-APSFT
AQVVLLNQP---GQISAAEAPVLD--------------------CHPAHIACKS-AELTE
-IDCCVGK-KLEDGPKFLKS--SDAAIIEMVPGKFMCAE-----SF--SPPLGR-FAIVI
----------------------------------------C--GIIKAVDKKAAGVGQVS
KSAKKALKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHIHIV-VIGHV-
DSDKST-T--TGHLNYKCG-SINKR--TIEKFEKEA-AEMGKGSFKEAW---VL-----D
KL-KAERERGI--TI-DTSLWK-----FENS--KCYMT--IIDRL-----NHRDFTKNMI
T----G-TSQAD-CAVLI-VAA-SVGEFE-------------------------------
------------------EHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIV-------KEKI-GYNP--DREAFVPISGWNGDNMLE-PS-----------
------------DGNTSGTMLL-----------EALDY---ILPPTHPTNKPLCLPLQ-D
---------------------TGVLKPG--M-VVTFAPVNI-KTEVKSVEMRHEAL----
----SE--TLSGDNVGFN-VK-----NVSVKDVRHGNDAGDSKDD-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHTACKF-AELKE
KMDRHVGK-KLEDGPNFLNS--GDAANVDMVPGKPVCVE-----CFSDYPPLGR-AAVHD
MRQT-VA---------------------------------V--DVIKAVNKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DLGKST-A--TGHLIYKCS-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDDP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-V----------------IAFVTVSGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNI-TTEVKSVKMHHEAL----
----NE--ALPGDNVGFS-VK-----NVSVKDDRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIAGKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKI

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 345)

HINIV-VIGHI-
DSGKST-T--SGHLIYKCG-GIDKR--TIEKLEKEA-AEMGKGSFKYAW---VL-----H
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNG---------------
-----------------REHALLA-YTLGMKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-ISTYIKKI-GYNP--DTVALVPISGWNGDNMLE-PS-----ANM-PC
-G----------------------------------------------------------
----------------TLLLETGILKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-LA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKTQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPACPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHETL----
----SE--ALPGDNVGFN-VK-----NVSVKDVCRGN

ENSGT00910000144046_0_Linker_0_1 (518, 529)

VAGDSKDD-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPSLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKVQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MY---LQEWAKPTDKPLCLPLQ-D
IYK----IGG--GTVPVEQM

PF03144 // ENSGT00910000144046_0_Domain_0 (441, 501)

QTGVLKPG--M-MVTFAPVNV-TSEVKSIEMHLEVL----
----SE--ALPRNNVGFN-V

ENSGT00910000144046_0_Linker_0_1 (501, 536)

K----------DVLCGNMAEDNKND-L-PM---E-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 709)

AAGFM
ARVIILNHP---GQISAVYVPLLD--------------------CHIPHIAHKF-EKKK-
-------K-KLEDGPKFLKS--DDAAIVDMVPRNLKCFE-----NFSDYPPLVH-FPVCN
MRQM-IA---------------------------------V--GVIKAVDKKAARANKVT
KSAQKA------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHM-
DSGKST-T--TGHLIYKCG-GIDKR--TIEEFEKEA-AEMGKGSFKYAW---VL-----G
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDVP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YKEIVEE-VSTYINKI-GYNP--DTVAFVPISGWNGDMLE---------------
--PRW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTCPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGQVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E-A----
--

PF03143 // ENSGT00910000144046_0_Domain_1 (543, 709)

VIILNHP---GQISAGYAPVLY--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IVDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTKPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNHP---GQISAGYVPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-LL--C
S-ML--------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAGGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------

PF00009 // ENSGT00910000144046_0_Domain_0 (191, 349)

AD-CAVLI-FAA-GAGEFEAGI---------SKNMQT-------------
------------------EHALLA-YRPGVKQLIVGVN--------KMDFTEQPKS--RK
R----YDKIIEE-VSTYVKKI-GYIL--DIVAFVPVSGWNNILQLS-AN-----V---TC
-FQGW--VT-QKDGNASGTVLS-----------ETLDC---TLLPTHPADEH----LH-D
VYV----IGDI-SSVPEGRLVFL-------K-LVTFAPVSV-TTEVKSVEMHHEAL----
----SE--ALLWGSMGFN-GK-----NISVKGVPCGDVAGDSKND-P-LM---E-AV

PF03143 // ENSGT00910000144046_0_Domain_1 (538, 673)

GFM
AHWIILNSP-------SQISARLD--------------------CHIAHIAGKF-AELKE
KIVHCSRK-KAEDGPTFLKS--GDAAVD-RIPGKPMCV------EFWYYSPLGR-FVVGD
MRQL-LVGVIIAVE----------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------ETSKYY
V----T-IIDAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLG------------------------------K
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 701)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGP-V----
------A---------------------------------V--GVIKAVDKKAAGSAQKA
------QKAK--------------------------------------------------
----------------------------------------

------------------------------------------TGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHINII-IIRCV-
NSGKSAAT--YPDLTHECG-RIDQK--PIEKFKTEA-AEMGKGSFKSAR----L-----D
KL-EAEHECGI--PS-DSSLWE-----FET--------------------GHRDFIRNMI
T----G-TSRAD-SAALI-VAA-HVGEFVAGI---------SQNGQT-------------
-----------------RKDALLA-YTRGVKQLIVGVS--------TVDCTEPPDS---I
R----YEEIIKE-VSAYIKNI-GYNP--DRVAFVPISGWNGDNMLE-PS-----APM-LG
-SKGW-KIT-PQDGNARVTTLL-----------EALDC---ILPPT---------PLQ-D
VCK----IVGI-GTVPGGKVEAGVLKPG--M-VVTFAPVND-TTEVKSVETHHESL----
----SE--ALPWDNVGFN-VM-----NASVQDV-QGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

LM---E-AAGF-
-----LNHP---GHISAGCADVLD--------------------CHPAYIACKF-AELNE
KMDHHSGK-TVEAGPKFLKS--GDAAIIDMMPVQPMCVE-----SFPDPPPLGR-VAVRE
RRQT-VA---------------------------------M--DVIKAVD-KAAGAGKVT
KSAQKPT-----------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-VSGYMEEI-SYNP--DTVALVPISGRNGDSMLE-PS-----ASM-PL
------------SGNASGTTLL-----------GALDC---VLPPARPTDKPLRLSLQ-D
VYK----VGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKAG--L-MVTFSPVSV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGLS-VK-----NVSVKDVRRGT

ENSGT00910000144046_0_Linker_0_1 (518, 537)

VAGDSKND-P-PM---E-A

PF03143 // ENSGT00910000144046_0_Domain_1 (537, 652)

AGLP
ALVIILNHP---GQVNAGYAPVLD--------------------CHTAHIACKF-AELKE
KMDRRSGK-KLGDGPEFLKS--GDAAIVDMVPGTPMGVE-----SFSDCPPL--------
-----------------------------------------------AVDKKAAGAGRVT
NSSRKLRRLNE--YYPQYLPPQS-------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FDTS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-ISQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-A------TVAFVPISGWNGDNMLE-PS-----------
-------VT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPT-----GVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPEDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AHVIILNHP---CQVSAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGC-FAVHD
MRQT-VV---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
-----------------------------------------KGSFKYAW---VL-----D
KL-KAEHERGI--TT-DISLWK-----FETG--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAV-GVGEFEAAI---------SKNGRP-------------
-----------------M-----S-LYTGVKQLIVSVN--------KMDSTEPPYS--QK
R----NEEIVKE-VSTYIKKI-VYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTCPTDKPLRLPLQ-D
AYK----NGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVE-GVLQPS--M-VVTLAPVNV-TTKVKSVEMHHEAL----
----SE--ALPGDNVGFN-VE-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 529)

VTGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTVHIACKF-AELKE
KIDHRSGK-KLEDGPKFLIS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGC-FAVRD
MRQT-VA---------------------------------V--GVIKALDKKAAGVGKVT
KSAQKAK-----------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHA-
DSGKST-T--TGHLIYKCG-GIEKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----N
KL-KAEHERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DIVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-CKDGNASETTLL-----------EALDC---ILPPTHPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVCRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAVFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----

PF00009 // ENSGT00910000144046_0_Domain_0 (126, 345)

EHEC--GITI-DISLWK-----FETS--KYYVT--ITAAP-----GHKDFIKNMI
T----G-TSQVD-CAVLI-VAA-GVGEFKAGI---------SKNGQT-------------
-----------------GEHALLL-AY--------IVN--------KMNSTETPYS--QK
R----YEETVKE-VSIYIKKI-GYNS--DTVAFVPISCWNGDNMLQ-PS-----A---N-
-------VP-CLVTHKDGSPLQ-----------L-------------P--------LQ-D
VYK----ISGI-AAVPVGRVETGVMRPG--I-VVTCAPVSV-T---------TEAL----
----SE--AFPGDSVGFN-VK-----NVSVKDVHWGNVACDSKND-P-PM---G-ASGFT
A-----------

PF03143 // ENSGT00910000144046_0_Domain_1 (553, 656)

-QISAGYNPVLD--------------------CLTAHIASKF-AELKE
-IDHQSDK-KLEDGPKFLKS--GDAVIV-D-------M------V-PGKP---M-FTVGV
---------------------------------------------IKAVDKKAAGADKAA
KSAQKVQKAT--------------------------------------------------
----------------------------------------

---------------------------------------TGKEK---THINVV-VIGHV-
DSGKSA-T--TGHLIYKCG-GINKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYV-------P-----GHRA-FKNMI
T----G-ISQAD-CTVLI-VTA-GVGEFEAGI---------SKNGQT-------------
-----------------HEHALLA-YNLGVKQ----------------------------
-------EIVTE-VRTYIKTI-GYNH---TVVFVPISGWNGDSMLE-PS-----ANM-PW
-FKGW-KVT-R-DGNASGTTLL-----------EALDC---ILPPTRPTDKPL-LPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLLPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRHGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDK-AAGAGKVT
KSAQKAQKSK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DLSLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAG-CAVLI-VAA---DEFKAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QM
S----TKLVVL------------------------------------------------V
-L----------------------------------------------------------
----------------FLLA

PF03144 // ENSGT00910000144046_0_Domain_0 (441, 518)

VTGVLKPS--M-VVTFAAVSV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
NIDRCSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYLPLGR-FAVRD
MRQI-VV---------------------------------V--GVIKAVDKKAAGDGKVT
TSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIGKFEKEA-AEMGKGSFRYAW---VL-----D
KL-KAERERGI--TI-DTSLWK-----FETS--KYYVT--ITDAA-----GHRDFIKNMI
T----G-TSQAD-CL--I-VAA-GVGEFEAGI---------SK-----------------
------------------------------------------------------------
--------------------------------------NNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGKASGTTLL-----------EALAC---ILPPTHPTDMPLHLPLQ-D
IYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NGSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 529)

AGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFM
AQVIILNLP---GQISAGYAPVLD--------------------CHTVHIACKF-ADLKE
KRDHHSGR-KLEDGPKFLKS--GDAAIVDMIPGKPRCVE-----SFSDYPPLGRCFAVHG
MRQT-VA---------------------------------V--SVIKAVDKKAAGAGKVT
KSPQKAQKAN--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 407)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KIT-RKDGSASGTTLL-----------EAXDC---ILPTRTD----LRLP-Q-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 403)

KTHINII-IIGQV-
DSGKS-----TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKSSFKYAW---VL-----D
KL-KAEHERGI--TI-DISLWK-----FET---KYYVT--ITDAP-----GHRAFIKSMI
TGRSLC-GPDCC-C---------WCWEFEASI---------CKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGVN--------KMDSTEPSYS--QK
R----YEEIIKE-VSTYIKKI-SFNP--NTVAFVPISVWNGDNMLE-PS-----ANM-PW
-FKRC-KVT-CKDGNASGTTLV-----------EALDC---ILPPTHPTDKPLCLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-ATEVKSVEMHHEAL----
----SE--DLPGDNVGFN-VK-----NVSVKDVHCGNVAGNSK-D-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFM
AQVIFLNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDYCSGK-KLEDSPKFLKS--GDAAIVYMVPGKPMCVE-----SFSDYPLPGR-FAVGD
MRQT-VA---------------------------------V--GVIQAVDKKAAGAGQVS
KSAQEAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHIIII-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TVEKFDKEA-TQMGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAVI---------SKNGQT-------------
-----------------CEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
G----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-LKDGSASGTTLL-----------EALDC---ILPPTCSTDKP----LQ-D
VYK----IGGI-GTVPVGRVETGVLKTG--M-VVTFAPVSV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRCGNVAGDSKND-P-PV--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACRF-AELKE
KTDCPSGK-KLEDGPKFLKS--GDAAIIDMVPGKPMCVE-----SFSDYPPRGH-FAVPD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMRKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETG--KYYVT--IIDAP-----GHKDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEYEAGI---------SKNGQT-------------
-----------------REYALLA-HTLGVKQLIVGVN--------KMDSTESPYS--QK
R----YKEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNVSGTTLL-----------ETLDC---ILPPTRPTGKPLRLPLQ-D
MYK----IAGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--V-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKKD-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFFDYPPLGG-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

---------------------------------------MG---KE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINII-VIGHV-
DLGKST-T--TGHLIYKCG-GIDKR--TIENFEKEA-AEMGKDSFKYAW---IL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDYIKNMI
T----G-TTQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLQ------------------------------K
R----YEEIVKE-VSTYIKKI-GY-P--DSVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASRTTLL-----------EALYC---LLPPTHPTDKPLRLPLQ-D
VYK----IGGI-GTIPVRRVETGVLKPG--M-VVTFAAVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGESKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GKISAGYAPVLD--------------------CHAAHIACKC-AELKE
KIDRHSGK-KLEDGPKFLKS--GDASIVDMVAGKPMCVE-----SFSDYLPLGH-FAVRD
MRQK-VA---------------------------------V--GVIKAVDKKVAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

---------------------------------KPALYLKAKMGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------ISTYIKKI-GYHPDT-VALFVPVSGWKGDDRLE-PG-----ANM-PW
-VKGW-KVP-REDGDAG--THC-----------SELGC---IPPPTRPPAKPLHLPLR-D
ACK----IGGV-GTGPGA--EGGCLAGG------HLAPVNV-TPEGKCGN-----AP---
-GRWSE--ALPGDNVGFD-VK-----SVSVKDVRRGDAAGDSNKD-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 667)

PV---E-AAGFA
AQVILLN-P---GQIGAGHAPVLG--------------------RPAAHSACKF-AELKG
KVDRRSGK-KLEDGPKFVKS--GD-----VVPGKPMCVE-----SFSDHPPLGR-FAARD
MRQT-VA------------------------------------DVLKAEDKKAAGAGRVP
QSAQKAQEAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DLGKST-T--AGHLIYKCG-GINKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAECEHGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMV
T----G-TSQAD-CAVLI-VAA-GIGEFEAGI---------SKNGQT-------------
-----------------REHILLA-YILGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-SL
-FKGW-K-----DGSASGTMLL-----------EALDC---ILPPTHPTDKLLHLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-RTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 543)

VAGDSKND-PPM-----------
EA

PF03143 // ENSGT00910000144046_0_Domain_1 (543, 709)

VIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIIDMVPGKPMCVE-----SFSDYPPLGC-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKA-------
---------AGADKVTKSAQKAQ---------KAK-------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
----SA-P--

PF00009 // ENSGT00910000144046_0_Domain_0 (71, 444)

TGHLIYKCG-GINKR--SIKKFEKEA-AEMGNGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FEAS--KYCTA--IIDAP-----GHR-------
-----G-TSQAD-SAVLV-VAA-GVGEFEAGV---------SKNWQT-------------
-----------------REHALLA-YTLAVKQLIISVN--------KMDFTEPPHS--QK
R----YEE-------IYIKKI-GYNP--NTVAFVPTSGWNGDNTLE-PT-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------ETV------------------------
-----------------------VLKPG--M-VVTFAPVNS-TTEVKSVEMHHEAL----
----SE--ASSGDNVGFH-VK-----NVSVKDVRHGNNAGDSKND-P-------------
----------------A

PF03143 // ENSGT00910000144046_0_Domain_1 (558, 709)

GCAPVLD--------------------CHMAHIACKF-AELKG
KIDCYSGK-KLEDGPKFLKS--GDVAIIDMVPGKPMCIE-----SFSDYPPLGC-FAIRD
MRQT-FA---------------------------------V--GVIKAVDKKAAGAGKVT
KSPQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
----FT-P-

PF00009 // ENSGT00910000144046_0_Domain_0 (70, 380)

-TGHLIYKCG-GINKR--SIKKFEKEA-VEMGKGSFKYAW---VL-----D
KL-KAEHECGI--TI-DISLWK-----FEAS--KYCTT--IIDAP-----GHRGFIKNMI
T----G-TSQAD-SAVLV-VAA-GVGEFEAGV---------SKNWQT-------------
-----------------REHALLA-YTLAVKQLIISVN--------KMDFTEPSHS--QK
R----YEEIY-------IKKI-GYNP--DTVAFVPISGWNGDNMLE-PT-----ANM-PW
-FKGW-KVT-RKDGNASGTMLL-----------ET-------------------------
----------------------VVLKPG--M-VVTFAPVNS-TTEVKSVEMHHEAL----
----SE--AFSGDNVGFH-VK-----NVSVKDVRHGNNAGDSKND-P-------------
----------------

PF03143 // ENSGT00910000144046_0_Domain_1 (557, 709)

AGYAPVLD--------------------CHTAHIACKF-AELKG
KIDCYSGK-KLEDGPKFLKS--GDIAIIDMVPGKPMCIE-----SFSDYPPLGC-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSPQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--AGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHLEAL----
----SE--ALPGDNMGFN-VK-----NVSVKDVHRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 652)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLDS-VC--L
C-SK-V------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAGGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYI----
--------------STYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVCD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
RDGLKYEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNS-------VEMHMN------
---------SSRGQRGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHICLKR-LI---
----AVWK-NVGGWPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGNP-
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------PS-DLQMWWHRQTI

PF00009 // ENSGT00910000144046_0_Domain_0 (148, 404)

ERTS--KYYVT--IIDAS-----GHRDY-QNMI
I----G-TVQAD-CAVLI-VAA-GVSEFEAGI---------SKNRQT-------------
-----------------HECALLA-YTLGVKQLIVGVN--------KMDSTEPPYT--QK
R----YEEIVKE-VSTYIKKI-GYNP--NT-TFVPISSWNGDNMLE-PS-----ANM-PW
-FWGW-KVT-HKDGNASGTTLL-----------EALDY---ILPPTHPTDKPLQLPLQ-D
IYK----MVVS-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TIEVKSVEMHHEAL----
----SE--ALPGDSVGFN-VK-----NVSVIDVRRGNSAGYSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGLT
AQVIIQNHL---CQISAGYASLLD--------------------CHI-------FAELKE
KIDHRSGK-NLEDSPKFLKF--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FAVLD
MKQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 335)

KTHIHIV-IIGHV-
DSGKSI-N--TGHLIYKCC-GTDKR--TTEKFEKEA-AETGQSSFRYAW---VL-----N
KL-KSKHENEHDITV-DFFLWK-----SETI--KYYVT--IIDVP-----GHRGFIKNNT
G----TPWAQAE-CFVLI-AAA-GVGELKAGI---------SRNGQT-------------
-----------------PKHALLS-NTLGVKQLTVGVN--------NMDSIELYDS--QK
R----YKDLVKE-VSTYIKKI-GYLP--DTVAIMPI-GENGDNVLE-PN-----ANM-PW
-FKEW-EVT-HKDGNASQSCCL-----------KLLIA---FLPPTHPIDKPLILPAK-H
IYK----NWWH-RYCPCG-VKTSVPKSS--I-LITFAPV---TTEVKSIEMYHEAL----
----SE--ALPGDNVLFN-FK-----NVSVKDVHHGNMTGDSIND-P-PV---K

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 705)

-AAGFT
AQVITLNHY----------THLYC--------------------TVTAHSACKL-AELKE
VTVIL--E-KSWNGSKFLKS--GDVAITNMIPGKPMYVE-----SISDYLVPEC-FAVSD
MRQT-VA---------------------------------L--RVTKAVDKNAAGAGKII
RSAQKAQKPK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSLKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-VAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQRAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------A

PF00009 // ENSGT00910000144046_0_Domain_0 (132, 345)

GITI-DISPWK-----LETS--KYYVT--SIDAP-----GHGGFIKNVI
S------TSQAG-CTVLI-VAA-GVGDFEAGI---------SRMGRP-------------
-----------------RRT-PLA-RTLSMKQLITDIN--------KR----NFFS--QK
R----YVEIVKE-VSTYKK-L-ATTP----THFVPISGWNGDNVLE-RS-----AST-PW
-FEGW-KVT-RKDCNASGTMLR-----------ENPHD---IL-PSHPTGKPFGLALW-D
IHK----IRGI-GAVPVGQVAPGVLRPG--V-MVTFAPVNI-ITEVKRVEMYHEVL----
--RDSP--AFPGDTVGFN-AK-----NAPVKNVHHGNLSGESKND-P-PR----------
VQG

PF03143 // ENSGT00910000144046_0_Domain_1 (544, 709)

IIQNHP---DQISAGYAPVLD--------------------SHTAHTACQV-CWAEK
WVRGRQGG-KLEDGPTFSES--GDAAIVNIVADKPMWVE-----HFSDYPPLCY-FAVPD
ARQR-VV---------------------------------V--GVIGAVAKKATGTG---
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTYINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIENFEKEA-AEMGKGFFKYAW---VL-----D
KL-KAERERGF--TI-DISLWK-----FETS--KYYVT--IVDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFE-------------------------------
-----------------AEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANI-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-G

PF03144 // ENSGT00910000144046_0_Domain_0 (434, 518)

TAPVGQVETGVLKPG--M-VVTFAPVNI-TTKVKSVKMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-LM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
VQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KLIAVPVK-KLENGPKFLKS--GDAAIVDMVLGKPMCVE-----SFSDYPTLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSVQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINII-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFKKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 602)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
MVRADPSS----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------IPNEHPNIPIY-PIL

PF00009 // ENSGT00910000144046_0_Domain_0 (58, 345)

DT-
DSGRPI-T--TNHLIYKYG--GKQR--IIKKFDKEA-AEMGKLSFKYAW---VL-----D
KL-KAECECGI--TI--HVLWV-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-RAVLI-VA--GVAEVEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKPLIIGVN--------KMDSTEPLYN--QK
R----YEEIIKE-VSIYTKKI-GYNP--DS-SLCPFFGLNGNNILE-P------ANM-PW
-FKEW-KVT-HRDSNASGTMLL-----------IAY------SSPTCPTDKPLCQSL--D
VYK----IGGV-GTVPVGQMETGVLILC--M-VVTFVPISV-TTEVKSVEMHHEAL----
----NE--AVPGDNVGLN-VK-----NVSVKDIHQGSVAGDSKNN-P--S---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 661)

-TAGFT
APVIMLSHP---R-INAVYASVLV--------------------CHTVHIACKF-AELKG
KIDHRSGK-RLEDNPKFLKS--GDAAIVDMVPYKPMCVE-----SFSDYPPLRS-FAVCD
VTDS--C---------------------------------C--GVIKAVDKKAPGAGKVT
QSAQKAQKAE--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIRHV-
DLGKST-T--TGHLIYKCS-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FEIS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNEQT-------------
-----------------QEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGD-ILE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGQVETGVLKPS--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNRP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FICC-
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MEKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 332)

KSHINIT-VIGHI-
DSNKTT-S--TGHLIYKRG-GINKR--TI-KFEKEA-AMMEKGSFKC-W---VL-----N
KL-KAERERGI--TT-DISLWQ-----FKTS--KCYVA--IVDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLL-VAA-GVGEFEAGY---------L---QE-------------
-----------------RADALLA-YALDVKQLIVSVN--------KMDSI----N--QK
G----YKEIIKE-ISTYIREI-GYNP--DTVVF----CYNGDNMLE-PS-----ANM-SW
-FKGQ-KVT-HKDSNASGIT-L-----------EILDY---ILLPTCSTDKPLRLPLQ-D
VYR----IGGI-GTVPVVWVEIGVLKPG--M-VVPFAPR-V-TTEAKSVEMHHGTL----
----TK--ALPGDNVGFN-VK-----EVSVKDVCPGNVTGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-ASGFR
TQMIILNYT---CQISAGYAPVLD--------------------RHTAHIACKF-AKLKE
KIDRCSGK-KAGRWPRFLKS--DEAAIVD------MCVE-----SFSDCPPLGY-FAVHD
-RQT-VT---------------------------------V--GIIKAVGKKAAGAGKVT
KLA---------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KIT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAGGAGKHP
PR---RSERIWYL-----------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHKDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REYALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 657)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--SDAAIVDTVPGKPMCVE-----SFSDYPPLGR-FM--C
S-AH-V----------------------------------------HI------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGFFKNAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--ITDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLS-VAA-GVGEFEAGI---------S------------------
---------------------KNG-Q--------------------TSEHALLAYT--QK
R----YEEIVKE-VNTYIKKI-GYNP--DSVAFVPIFGWNGDNMLE-PS-----ANT-PW
-FKGW-KVT-HE--NTSGTTLL-----------EALDC---ILPPTHPTDKPLHLS-E-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGQVETGVLKPG--M-VVTFALVNV-TTEVKSVEMHHEAL----
----SE--GLPADNVSFN-VK-----NVSVKDVHRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 529)

AGDSKNV-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDCRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVCD
MRQT-VA---------------------------------V--GVIKAVDKKAPGAGQVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------CKNWH--------------
-----------------PLHGLLA-YPLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAKG-------------------------------------------------
----------------------------------------

------------------------------------------WERKK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 396)

AQINIV-ITGHV-
LIDVTK-STTTEHLIYRGG-GIDKR--TVENF-EMKATEMGKSCFKYAW---VL-----D
KL-KTEYDCG--NAI-GIPLWK-----FETS--KYYVT--IFDAP-----EHRDLIKNMI
T----G-TSQAG-CAALI-FAA-N--EFDAKI---------SEW-QT-------------
-----------------NDNALLA-HTPDMKQLIISVK--------QNGLPEPPHG--QK
R----YEDMIRE-VSTYFKKI-DRDP--NMVAFVTISGRNGDNMLE-PT-----AHM-PW
-FKGS-WDR--KDDSVSGTMLL-----------EALDC---ILSLSCPAYKPLHLPIQ-D
IKKK-MVVLVL-TRGPGGDWCSQTRGGV--V-VID-----T-MKVR-NVEMHHEIL----
----SE--DFPGDKMGFN-VK-----NISVKYACCGSVSGDSKN-DP-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 705)

PK---E-AAGFI
DPVIILNHP---GQIRVGY----P--------------------CHTSHITCKF-TEVKE
MIDCCSGK-KLEDGSKFLKS------------GGALIIDMVSSKSFSDSPPMGH-VAVHD
IRQA------------------------------------V--GVIKTVDKKAVRAGKVT
MSAQKARRLNG-------------------------------------------------
----------------------------------------

-------------------------------------------------

PF00009 // ENSGT00910000144046_0_Domain_0 (50, 404)

INIV-IIGHV-
DLGKST-LVYTGQLIYKYG-RINKR--TIEK--FEEASEMGKGSFKYAQ---VL-----D
KL-KAECEYV--ITI-DISLWK-----FETS--KYFVT--IVDAA-----GHRDFIKNMI
T----G-TSQAD-CTVLI-FAA-GVGEFEPGI---------CKNGT--------------
-----------------RDHALLA-YMLGAKQLIIGVN--------KMGTIETHYS--QK
R----YEEIIKE-GSTYIKKT-GYKP--D-VAFMLVSGWSGDNMLD-PA------NR-PW
-FKGW-KVT-HKDNNASRTMLL-----------EALDC---ILPSLRPADNPLYLPQD-V
YNI-----GGI-DTVPMGGVKTGVLKLD--M-VVSFPPVSV-TTEI-KLL-HCEAL----
----SE--ALPGDSVGFN-IK-----NIAVKDVEHGLHVRGPEFNSQ-YL---E-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 709)

AADIT
AQVIILNYP---GQISAGYAPVLD--------------------CADI--ACKF-AELKE
KIDCHAGK-KLENVPKFLKS------------GDVDIVD-----SFSSYPFLGS-FALCD
IRQT-VA---------------------------------V--VVIKAVDKRLLELTMSP
SLPRNLRRLNEYYS----------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHFNIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQA-------------
-----------------TEHALLA-YTLGVKQLIVGGN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKNVQHGNVAGDSKNN-P-PI---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHL---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

-----------------------------MKTTHKSQNGEGKDSHQHRHHRTC-RFE---
---QVH-H--YWPSDLQFG-GIDKR--TIEKFEKEA-TEMGKGSFQYAW---VL-----E
KL-KAEREHGI--TI-DLSLWN-----SKTS--KYYVT--LIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SNNGQS-------------
-----------------REHGLLA-YTLGVKQLIVGVN--------KMDSTELPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRAETGVLKPS--M-MVTFAPVNV-ITEVKSVEMYHEAL----
----SK--ALPGNNVGFN-IK-----NVSIKDVHSGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVLILNHP---GQISAGYTPVLD--------------------CHTAHIACKF-AELKE
KIDCHSAK-KLEDGSKFLKS--GDAAMVDMVPGKPMCVE-----SFLDYPPLGR-FAVHD
MRHT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQTAK--------------------------------------------------
----------------------------------------

------------------------------------------WGRKRLNINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GTDKR--TIEKFKKEA-AEMGKGSFKYAW---VL-----D
KL-KAEREHGI--TI-DISLWK-----FETS--KYYVT--IIDAA-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGV---------SKNRQT-------------
-----------------HEHALLP-YTLGVKQLIVGVN--------KMDSTDPPYS--QK
R----YKEIVKE-VSTYVKKI-GYNP--DTVAFVPISGWNGDSMLE-SS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALNC---ILPPTQPTDKPLRLPLQ-D
IYK----IDGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKTIEMHHEAL----
----SE--ALPWDNVGFN-VK-----NISVKDVCRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-S-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDCCSGK-KLEDGPKFLKY--GDAAIIDMVPGKPMCVE-----SSSDSPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKFT
SLPRK----------------LK---------G---------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 407)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KIS-RKEGSGSGTTLL-----------EALDC---ILPPSRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--AMPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AGTFT
AQVIILNHP---GQIGAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDNPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKGK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------KE------------------ATEMGKSSFKYDRVLD--------------
----------------------------------NLKT---ESEHGIITDNSLWKFGASK
CLQ----DWCI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPFGHVEIGVLKLE--I-VVTFAPVNV-TTEAKSVEMYHEAL----
----SE--ALPGDHVDFN-VK-----NMSVKDVRHGNVAGDSKND-P-LM---E-AAGFT
AQ---------------------------------------------------F-AKLKE
KIDRR----------------------------------------------SGC-FTVLD
MKQI-IA---------------------------------T--GAIKAVDKKTAGAGKVS
PSPTLPQIGEGES-----APNGL-----VG-KEAGDVRNVLNSVKMRKGVAPS-----GT
RGEGAQNSVISGIDAFQQQKLTTSQSASKIQQRDSVEDKH

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------K

PF03143 // ENSGT00910000144046_0_Domain_1 (609, 710)

-KLEDGSMFLKS--GDAAIIDMVPGKLMCVD-----SFSDNPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAARTGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 661)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPP--L-GR--F
N-T--I----------------------------------------EFCCSWRG------
------------------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---MGK

PF00009 // ENSGT00910000144046_0_Domain_0 (127, 404)

HEHGI--TI-DISVWK-----FETS--KYYVT--ITDAP-----GHRDFIKNMI
TGQITG-TSQAD-CAVLI-VAA-DVGEFEAGI---------SKNRQT-------------
-----------------RDHALLA-YTLGVKQLIIGVN--------KMDSTEPPYS--QK
R----YKEIVKE-VSTYIKKI-GYKP--DTVAFMPISGWNGGSMLE-PS-----TNM-PW
-LKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTCPTDKPLRLPLQ-D
VYK----IGGI-GIIPVGRVETGVLKPG--M-VVTFAPVSV-TTEVKSVEMHHEAL----
----SE--AFPGDNVGFN-VK-----NVSVKDLRRGNVAGDGKTE-P-PM---E-AAGFS
A-----------

PF03143 // ENSGT00910000144046_0_Domain_1 (553, 720)

-QISAGHAPVLD--------------------CHTAHITCEF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVK-----SFCNYPPLGC-FAVCD
MRHT--------------------------------------------VDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------

PF03144 // ENSGT00910000144046_0_Domain_0 (445, 501)

LKPG--M-VVIFTPVNT-TSEINSVEMHHEAL----
----SE--TLPADNVGFN-V

ENSGT00910000144046_0_Linker_0_1 (501, 529)

K-----HAS-QNVRCGNVGGNS-KN-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

LM---E-AAGFT
AQVTILTHP---VQISADYAPVLD--------------------CHTAHNYSQL-CSAEG
ETDHHSGK-KLEDRLKFLKS--VDAAITDTIPGKPIYVK-----SFSKYPPLAV-LLLMT
CR-A-VA---------------------------------V--LVIKAVDKKAAGASKVT
KSAQKKNKIK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

-------------------------------------------------

PF00009 // ENSGT00910000144046_0_Domain_0 (50, 404)

INII-VIGHV-
DSGKST-T--TGHLIYKSD-GMDKR--IIEKFEKEA-AEMGKCSFKYAW---VL-----D
KL-KAERDCGI--TI-DISLWK-----FETS--KYYD---------------TDFIKNMN
T----G-TSQAD-CAVLI-VAA-GIGEFEAGI---------SKNGQT-------------
-----------------REHVLLA-YTLGVKQLIVGVN--------KMDSTEPLYS--QK
R----YEEIVKE-VSIYIKKI-GYNT--DTLAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-CKDGSANGTTLL-----------EALDC---ILPPTHPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGILKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----NE--ALPGDNIDFN-VK-----NVSVKDVCRGNVASDSKND-P-PM---E-AAGS

PF03143 // ENSGT00910000144046_0_Domain_1 (540, 629)

T
AQVIILNHP---GQISAGYAPILD--------------------CHTAHIACKF-AELKE
KIDCHSSK-KLEDGPKFLKS--GDAAIVDNGSRKTHLYM-----RQ--TVGVGV-IKAVD
----------------------------------------------------KK------
-SAQKAQKTK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
---------------------------------------MGKGCFRYVW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--EYYVT--IIDAP-----GHRDFNKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNRET-------------
-----------------CEHALLA-YTL-----------------------VPPYS--QK
R----YKEIVKE-VSTYIKKI-GYNP--DTAALVPISGWNGDTMLE-PS-----ANM-SW
-FKGW-KVT-WKDGNTSGTTLL-----------EALSC---ILPPTRPTDKPLHLPLQ-E
VYK----SGSI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVSRVETGVLKPD--M-VVTFARVNV-TTEVRSVEMHHEAL----
----SE--ALPGDNMGFN-IK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AEVIILNHT---GQISAGYATVLD--------------------CHTAHIACKF-AELKE
KNGCRSAK-KLEDSPKFLKS--SDAIIVDMVPGKPMGVE-----SFSDYPPQGR-FALRD
MRKT-VA---------------------------------V--GVIKAVDKTAAGAGEVT
KSAQQAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-VSTYIKKT-GCNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PC
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTPPTDKPLRLPLQ-D
VYK----IGGI-GTVPVDRVETGVLKPG--M-VVTFAPVSV-TTEVKSVEMHHEAL----
----SE--K------------------VSVKDVHRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------GHTAHIACKF-AELKE
KIDRRSGK-KLKDGPKFLKS--GDAAIVDMVPHKSMCVE-----SFSDYPPLGH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------LEKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 339)

KTHINIV-IIGHI-
VLGKFN-H--IDHLIYKCG-GIDKE--IINKCEKETAAEMGKVILQYIW---SLK-----
----LKVVCEQSNII-DISLWN-----IEID--KNYMP-------------HYPGLETMI
T----A-TSQAD-CTAPI-VAC-GIGEFEAGI---------SKNGED-------------
-----------------SEYALLT-YTEGVKQLIVGVI--------KMDSTESHYT--HK
R----YEE-----ISTYIKKI-RYNL------FVLISGCYADNTME-PS-----ANM-PC
-FKGW-KFT-CKDN-VSGNKAL-----------EALDC---IRPP-HPTDKFLCLPLQ-N
IR--------Y-GTVPG----------------------DI-TTEV-NVEMHHEIL----
----SE--VLPGDNVGCR-IK-----NMSIKDVCHGNVAGS-KKD-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 707)

-E-AASFT
AQVIILNHP---GQISAGCATVLD--------------------CYTAQIACKF-ADLEE
KIDCPSTK-KLDNGPKFLKS--GDAAIIHIVPGKP-CVA-----SFSDYHPLGH-FAVHN
MRQT-VA------------------------------------GVIKAMGKKVAGDGKVT
KFAHRAQETK--------------------------------------------------
----------------------------------------

------------------------------------------NGKEKTHINIV-VIRHV-
VSGKFT-A--TGPLIYKCG-GIHKR--TIKKFEKEA-A-WEKSSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHK----NMI
T----G-TSQAD-CAVLT-VAA-GVVELEAGI---------SKNGQT-------------
-----------------RERALSGLVTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIIKE-VRTYIKKI-GYNP--NTVAFVPISRWNGDNMME-PS-----ANM-PW
-FKGW-KIT-RKDGNASGTTLR-----------EALDC---ILPPTHPTGKPLRLPLQ-N
VYK----IGVI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGQVETGVLKPGGGM-GVTFAPVNV-ITEVKSVEMHHEAS----
----SE--VLP-DNVGFN-VK-----NVSVKDVHRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-APGFT
AQVIILNHP---GQISAGCAPVLD--------------------RHTAHIACKF-AELKE
KIDCCSGK-KLEDSPKFLKS--GDAAIVNMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIQAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------IDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAF--------------PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTHPTDKPLCLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 516)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSFEMHHEAL----
----SE--ALPGDSVGFN-VK-----NVSVKDVCR

ENSGT00910000144046_0_Linker_0_1 (516, 535)

GIVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLENGPKFLKS--GDAAIVDIVPGKPMCVE-----SFSDYPPLGR-FAVRD
KRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 653)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGL-SL--C
C-S--G----------------------------------------WGLVAQSGLNATFA
SWVQAILLPQPPK-----------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 637)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPIHYS-----I---------------
----------------------------------------------------CCI-----
----CLS-----------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------SD-CRFQM-TAP-GICKLEVNV---------SKNGQN-------------
-----------------YKHALLA-YPLGVKQLIAGVK--------RMDSTEQPG---QK
S----YVEIVKE-VSNYIKKI-GYNP--DTVALVPSFA---DSMLQ-SR-----ADV-TF
-KG---NVT-CNDVSVCGTTLA-----------EALEY---ILP-LTHTGKALYLPXX-X
XXX----XXXX-XXXXXX------------X-XXXXXXXXX-XXXXXXXVE

PF03144 // ENSGT00910000144046_0_Domain_0 (472, 520)

HHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------CEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIIKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTHPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTVAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNLGFD-VK-----NVSVKDVRRGSVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISARYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKLT
KFAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYMT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E-AA---
-----------

PF03143 // ENSGT00910000144046_0_Domain_1 (552, 709)

-GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRCSGK-KLEDGPKFLKS--ADAAVVDMVPGKPMCVE-----SFSDYPP--L-GL--H
Y-S--F----------------------------------------------CCR-----
-------QSGGREYAKS-------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KVT-RKDGNANGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TAHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEHERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----EHRDFIKNMI
R----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VTGHI-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-YISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IVGI-GTVPVGRVETGVLQPG--M-VVTFAPVNV-TTEVKSVKMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRCGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 653)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGP-VSLLC
VYPS-QS---------------------------------C--NHEPAMPILGSMVLIIF
AN----------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 403)

KTHINII-ITGHV-
DLGKST-P--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----SETR--KYYLT--IIDPP-----GHSDFIKNMI
T----V-TSQAD-CAVLI-VAA-GVGEFKAGI---------SKNGQT-------------
-----------------REHALLA-YTLCVKQLIVGVN---------MDSTEPPYS--QK
R----YEETVKE-VSTYIKKI-DYNL--DTVAFVPVSGWNSDSMLE-PS-----ANM-PC
-LKGW-KVT-HKDGSASGTTLF-----------EALDC---ILPPTCPTDKPLWLPLQ-D
VYK----IGGT-GTIPVGRVETGVLKPG--M-VVTFTPISF-TTEVKSIEMHHEAL----
----SE--AFPGDNVSFN-VK-----NVSVKDVHCGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 657)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTGHIACKF-AELKE
KIDCWSGK-KLEDGPKFLKS--GDAAIVDLVPGKPMLCG-----GFSDYPPVGS-FHCSR
--------------------------------------------------YETD------
-SCCGCHQSSGQEGCWS-WQGHQFFPESSEG-----------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 458)

KTHTNII-VPEHM-
DGQ----V--YHHLIYKCG-GIDKR--TTEKFEQEA-AEVGKGSFRYAW---IL-----D
TL-RAE--CEHGIAI-DIPLWM-----PQ----------------------DTDFTKNMI
T----G-TSATD-CALIA--AA-GVAEFETGI---------SMNGQT-------------
-----------------WEHALLV-YTLSVKQLIVGGM--------EVDSIEPL------
------------------------------------------------------------
---------------------L-----------EVLDG---TLPPTYPTAKPLHLSAPPG
CLQ----IHGI-GTVPV---ETGILKPR--L-MAPSVPVNI-TTKANSVGMP---L----
----NE--ALPGDTVGLN-VK-----NMPVQELSH---DGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PL---E-AAGFT
AQLIISNRP---GQISAGCAP------------------------------CWF-VKLKQ
KINCHSGK-KLEDGPKFLKS--GVAAIIDMVPGKPMRVE-----SFSDYP-LCH-FAIRD
ITQM-VA---------------------------------V--VVIKAVDKKSAGAGEVT
KAERLGQRSK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MVS

PF03143 // ENSGT00910000144046_0_Domain_1 (633, 701)

GKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V-------VDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DLGKCT-T--TGHLIYKCG-VIDKR--KIKKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEHERGI--TT-DISLWK-----FETS--KYYVT--ITDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAV-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YALGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIIKE-VSMCIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----VNM-PW
-FKGW-KVT-CKEGNASGTTLL-----------EALDC---ILPPTHPTVKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGPVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHETL----
----SD--ALAGDNMGFN-VK-----NVSVKDVSHGN

ENSGT00910000144046_0_Linker_0_1 (518, 533)

VAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRCFGK-KVEDGPKFLKS--GDAAIIDMVPGKPKCVE-----SFSDYAPLGR-FAVHD
VRQI-VA---------------------------------V--GVIKAVAKK--------
--------AAGAGKVTKSAQKAQ---------KAK-------------------------
----------------------------------------

------------------------------------------MRKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 380)

KTHINII-VIGHV-
DSGKST-A--TGHLIYKCG-GINKR--TIEKFEQEA-AKIGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWN-----------KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFE----------------QT-------------
-----------------GEHALLA-YTLGVKQLIVAVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVI-RKDGSASGTTLL-----------------------------------E-D
VYK----IGGI-GTVPMGREDTGVLKPG--M-VVTFAPVSV-TTEVKSVEMHHKAV----
----SD--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 653)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHRSGK-KLENGPKFLKS--GDAAIVDMVPGQPMCVE-----SFSDYPPLGL------
------A---------------------------------V--GVIKAVDKKAAGAGKVT
KSSQKSQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 664)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FA--V
R-DM-S----------------------------------------FFPQSP-----RRN
HLLSCPEGSSF-------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTYINIV-IIGHV-
DSAKST-T--TGHLTYKCG-GIDKR--TIKKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDSIKNMI
T---------SG-CAVLI-VAA-GVGEFEPGI---------SKNGQI-------------
-----------------H------------------------------------------
--------------------------------------------VE-PS-----ANM-PW
-FKGW-KVT-HKDGNASGITLL-----------EALDC---ILQPTRPTDKPLCLPLQ-N
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPMGRVETGVLKPG--M-VVIFAPVIV-TTEVKSVEMHHEVL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHCGN

ENSGT00910000144046_0_Linker_0_1 (518, 529)

VTGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 720)

PM---E-AAGFT
AQAIILNHP---GQISAGYAPVLD--------------------CHTAHIACKL-AELKK
KIDHRSRK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPSLGH-FAV--
-------------------------------------------RVIKAVDKKAAGAGKVT
RSAPKAKKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-IIGHI-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNI-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPGLD--------------------CHTAHIACKF-AELKE
KIDCRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGG-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTRINIV-VIGHV-
VSGKST-T--SGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 657)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FA--C
C-SV-A----------------------------------------CP------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GFDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKIMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGKT-------------
-----------------HEHALLA-YTLGVKQLIVEVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTIAFVPISGWNGDNMLE-PS-----ANM-PW
-FKRW-KVT-CKDGNASGTTLL-----------EALDC---ILPHTHPTDKPLRLPLQ-D
VYK----IGGI-GTVLVGRVETGVLKPG--M-VVTFATVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-TAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRWSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FTVCD
MRQT-VA---------------------------------V--GVIKAVDKKVAGAGKVT
KSAQKVQKAK--------------------------------------------------
----------------------------------------

-------------------------------MGE------NFCNLE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINTV-IIGHI-
DSGKST-T--TGHLIYKRS-GVDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDLIKNMI
T----G-TSQAD-CAVLI-VAA-GFGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--HK
R----YEEIVKE-VSTYIKKI-GYNT--DTVAFVPVSGWKGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLCLPLQ-D
VYK----IGGT-GTVP-----TGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--------------------NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KTDRHSGK-KLEDGPKFLKS--GDAAIVDMVPGKPVCVE-----SFSDYPPLGR-FAVHD
IRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

--------------------------------------------MEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 404)

TYINIV-VTGHA-
DLGKSV-T--PGHLIYKCCCGIDKR--T-----------IEKFEKEAAK---MG-----K
---GSFKYLDI--TI-DISLWK-----FETS--KYYVM--IINAP-----GQRNFIKNMM
T----G-TPQPG-YPVLF-VAA-GVGEFEAA-----------------------------
--------------------SPPA-YTLDMKQPIVAVN--------KMGFTEPPCS--QK
R----YEEIVKE-VSTYIKKV-GCST--DMVEFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KFA-HKDGNASGTTLL-----------EALDC---ILPPTLANDNPLCLPLH-D
AYK----TSGI-GTVPTG-----ILKPG--M-VVTFAPVNI-TTEVKSVEMHHEAL----
----SE--ALPWDSVGFN-KE-----NMSVKDICRGGVAGDSKND-P-WM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-TAGFT
AQVIILNHP---GQIGVGYAPVLD--------------------CHTAHIACKF-AELKE
KIDCCSGK-KLEDGPKFLKS--GDAAIVNMVPGKPMCVE-----NFFDYPPLGC-FAVRD
MRQT-VA---------------------------------V------AVDKKSAGASKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERCI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GQRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IDGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNG-TTEVKSVEMHHEAL----
----SK--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQM-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHNNIV-VIGHV-
DSGTST-A--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
NL-KAECECGI--TI-DISLWK-----FETS--KYYVT--ITDAP-----GHRDFIKNMI
I----G-TSQAD-CVVLI-VAA-GVGELGAGI---------SKDGQT-------------
-----------------REHALLA-YTVGVKQLIVGVN--------KMDSTEPPSS--QK
R----YEEIIKE-VGTYIKKI-GYNP--NTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-PKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLQLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFALVNV-TTEIKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRGDSVADDSKID-P-SM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQGIILNHP---GQISAGYAPG-H--------------------CHMAHSACKF-AELKE
KIDHHSEK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKEAAGAGKVI
TSAQKAQKDK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------T-------------
-----------------CEHV-----LL

PF00009 // ENSGT00910000144046_0_Domain_0 (269, 404)

DVKQLIVEVN--------KMDSTKPRHS--Q-
-------KIVKE-VSTYIKKI-GYNP--GTVAFVPISDWNGDNMLE-PS-----PNT-PW
-FKRW-EVT-HMDVNASGTTLL-----------EALDC---ILPSACPSDQP----LQ-D
VCT----IAGI-GAAPMG--------PG--L-VVTFAPVSV-TTEVKSVEMHHEAL----
-------------SVGFH-VK-----NVSARDVCHNIVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQ-----APVLD--------------------CHAVHITCKF-AELQE
EIDCCCGE-KLEDGAKLLKF--GDATI-LMVPGQPMRFE-----KFSDYPPLGH-FAVCD
MSLT-VA---------------------------------V--GVIQAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-YISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTMLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IVGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRCGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FLRSC
CCTP-A------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTRINVV-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AGMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDTP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VGA-GIGEFEAGI---------SKNGQTREHALLAYILGVK
QLIVGEFEAGISKNGQTREHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFINV--
---------IAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 202)

KTHINIV-VIGHV-
DSGKST-A--TGHLIYKCG-GIDKR--TIEKSEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDDP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVSEFEASI---------SKNGR--------------
------------------------------------------------------------
----------------------------PEIAFVTVSGSNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYQ----IGGI-GTVPVGRGETGILKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----NE--ALPGDNVGFS-VK-----NVSVKDDRHGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIAGKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRA
LRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKVK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEEAHTNIS--INRI-
DSQKSI-M--PGHLIYECG-KIK-R--TIEKSEEEA--AEMEKCFKYNW---VW-----D
KQ-KAE--C-LGTTI-DISLWE-----FETS--RYYQQ--V---TIIKAFAHRNFIKNMM
A----G-TSQAD-HTVLI-HAA-VVGEFEAGISKG-----------P-------------
-----------------WEH-ALV-YTLSVRETIVGVN--------KVESTEPPCS--QK
R----YDAVVKE-VSTYNKTI-ASDP--DTITFVPITGWNGDNMRE-LS-----DNQ-PG
-CTE--KVT-RKKGNSSRPTLL-----------EALDC---ILLRTLPADKPLLFPLH-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETVVLKPG--L-VVTYAPGNP-TTEVKSIEMHHEAL----
----IE--ALPEDN--FN-VK-----NVSVKDVH-GSMA

ENSGT00910000144046_0_Linker_0_1 (520, 536)

GDSKHG-P-LM-----

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 710)

-ESFT
ARVTLLNHP---GQISAGDAPVLD--------------------CYPAHIAYTF-AELKE
KIDFYSAK-ELEDGLKHLKF--GDAPIIDMVPGRPTCVE-----SFPEYP-SGH-FPIQD
MRWT-IA---------------------------------L--GINKGKDQKVAGAGKVT
KSSQKKI-----------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAGGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MEKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 345)

KTHINII-IIGHM-
DSGKST-T--TGHLIYRCG-GIDKR--TLEKFEKEA-AEMGKGSINYAW---VL-----D
KL-KAKCEGII--TI-DSSLWT-----FETR---------------------KDFIKNVI
A----A-TSQGD-CAVLI-VTA-GVGEFEAGI---------SKKVQT-------------
-----------------HEHALLA-YTLGVRQLIAGVN--------KMDSTEPQYS--QK
R----YEEIVKD-VSTYIKKI-CYNP--DMIAFVPISGWKGDSMLE-PS-----ANM-PW
-SKGW-KVT-WKDGNASGTTLP-----------EVLDC---ILPPTHPTDKPLQL-LQ-D
VYK----IGGI-GTGPVGRVESAVLKPG--M-VVTFTPSV---------EMHHEGL----
----PMHFSSSGDNVGFN-IK-----NMSVKDIRCGSVAGDSKYY-L-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 652)

-E-A----
-AMIILKHP---GQISARYTSVLD--------------------CHTPHIACKF-AELKE
KIDHWSDK-KLEHGPKYFKS--GDAAVVDMVPGKPMCVE-----SFSDYPPLAV-DKKTA
GAVK-IT---------------------------------K--SAQKAQKPK--------
------------------------------------------------------------
----------------------------------------

---------------------------------------MGKEK---THINIV-VIRHV-
DSGKST-T--TGHLIYKCG-GINKR--TIEKFEKKA-AEMGKG-----------------
------------------------------------------------------------
-----S

PF00009 // ENSGT00910000144046_0_Domain_0 (187, 404)

-FKYAD-CAVLI-VVA-GVGEFEAGI---------SKNGQT-------------
-----------------YEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKT-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDDNASGTTLL-----------EALDC---ILPPTCLTDKPLWLPLQ-D
VYK----IGGI-GTVPVGLVETGVLKPG--M-V--------------SVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NMSVKYVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNYP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHWSGK-KLEDGPKFLKS--GDAAILDMVPGKPMCVE-----SFSDYPPLGH-FAVRD
MRQT-VT---------------------------------V--GFIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 103)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA--A---EXXXXXX---XX-----X
XX-XXXXXXXXXXXX-XXXXXX-----XXXX--XX--X--XXXXX-----X-XXXXXXXX
X----X-XXXXX-XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX-------------
-----------------XXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X----XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXX-XX-----XXX-X-
-XXXX-XXX------X------------------XXXX---XXXXXXXXXXXXXXXXX-X
XXX----IGTV-PGR-V----ETGVKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
---------------------------------------MGKGSFKY

PF00009 // ENSGT00910000144046_0_Domain_0 (108, 355)

AW---VL-----D
KL-KAEHERGI--TI-HISLWK-----FETS--EYYGT--ITDGP-----GHRDFIKNMI
T----G-TSQAD-CTVLI-VAA-GVGEFEA------------------------------
------------------EPALLA-YALGVKERIVGVN--------KMDSTE--------
-----YEEIIKE-VSTYIKKI-GYNP--TH------------------------TNM-PW
-FKGW-KAT-CKDGNASGTTLL-----------EALDC---NLPPTHP-----------D
VYK----IGGI-GTVPIGQVETGVLKPG--M-VVTFAPVNI-TTEAKSVEMHHKAL----
----SE--ALLGDNVGFN-VK-----NVSVKDLCRGNVAGDSKKD-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQTIILNHP---GQISPGYVP--------------------------------F-AELKE
KIDCHSGK-KLEDGPKFLKS--GDVAIVDMVSAKPMCVK-----SFSDYSPLCH-FAVCD
MRQT-VV---------------------------------V--GIIKAVDKKAAGAGKVA
KSA---------------------------------------------------------
----------------------------------------

------------------------------------------KGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIECI-
DLGKS--T--TGHMIYKCG-GIDKR--T-EKFEKEA-ADMGKGSFKYAV----L-----D
KL-KAECAYGI--TI-AISLWK-----FETS--KYYVT---TLFP-----GHRDFIKNLI
T----V-TSQAK-CVVLI-VAA-GVGEFEAGI---------SKNGEP-------------
-----------------GEHA-LA-YTVGVKQLIDGVN--------KMDSSEPPYC--QK
R----YKEIIKE-VSTYLEKI-GYKS--DTVTFVPISGWNDDNLME-PS-----ANM-PW
-FKGW-EVT-YKNGNASGSTLL-----------EALDC---ILPPTHPTDKP-CLPLP-D
IYK----ISGI-STVPGAE--WRLVSTG--I-VVIFPPVNV-TTQIKSIEMHHKAL----
----SE--AFLGDNVDFN-VS-----NIFVKDVHHGNVAGDSKND-P-PM---E-ASGFL
AQVIILNHP---ASLT--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------NGKGKTHINIV--IGHL-
DSCKSI-T--TGHLIYKCG-GIDKR--TIKKFEKEA-AEIGKGSFTYSW---IL-----N
KL-KAKHEHGI--TI-DFLLWK------ETI--NYYVT--ITDVP-----GHRHFIKNMI
I----G-TSQAD-CAALI-VAA-GVDEFKAGI---------SKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGVN--------KMDSTELSYS--QK
R----YKEIIKE-VNTYTKKI-GCNP--DTVAFVPI-GWNCDNMLE-PS-----ANM-SW
-FKGW-KVT-HKDGSASRTILL-----------EALDC---ILPPTHPADKPLLLPPQ-D
IYK----SGGM-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGQVETSVLKPS--I-VITFAPV---TTEAKSVEMHHEAW----
----SE--ALPGDNVVLN-VK-----NISVKDVHHGNMT

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKNG-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---K-TPGFT
AQVIILNHP---GQISSGYAPVLY--------------------HHISQ--CLQ-VCLAE
GGDCS------SFWKKFLKS--GDAAIIDMVLVKPMCVE-----SFSDYPPPGC-FAFSL
TRQM-VA---------------------------------L--GVTKVVDKKAAGAGKTT
KSSQNAQKSK--------------------------------------------------
----------------------------------------

---------------------------------------------MFRKENIV-VIEHV-
DSGKCT-T--TGHLIYKHG-GMDKR--TIEKLEKEA-AAMGKDSFKYAW---VL-----D
KL-KASGQRGI--AT-DFSLWK-----FESS--KYYVT--IIGAP-----GHRDFIKNMI
T----G-MFQAD-CAVPI-VAA-GVGKFEAGI---------SKNGQT-------------
-----------------RE---LA-YTLDVKQLIVGVN--------KMDSTEPLYI--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTV----------------PS-----ANT-PQ
-FKGR-KVT-HKDGRASGATLL-----------EALDC---VLPSTRPTDKPLRLPLQ-V
VYK----IGGV-EAAPV

PF03144 // ENSGT00910000144046_0_Domain_0 (438, 518)

GRVETGVLSPG--M-VVTFAPVDA-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NASVKGVLRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSNND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 592)

-AAGFT
AQVIILNHP---GQISAGVAPVLD--------------------CHTGRIAC--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHIN----IGHV-
DSGKST-T--TGHLIYKCS-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----N
KL-KAERERGI--TI-DISLWK-----FETS--KYYMT--IIGAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLCLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 653)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTIHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGL-SL--C
CHS---------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------------------------
----------------------------------------------------VL-----D
KL-KAK

PF00009 // ENSGT00910000144046_0_Domain_0 (127, 345)

CE-GI--TI-DISMGK-----CETN--KYYMT--IIDAS-----RLRDFFKNVI
I----G-TSQAN-SAVVI-VAP-GVGEFEEAI---------SKNGQT-------------
-----------------HEHVFWA-YTLVVKQLIVGV---------KMDSTEPHSS--QR
N----MREIVKE-VNTYVKKI-DYKP--DAVALVPISGWNGNNVLE-PS-----TNI-PW
-FKGW-KIT-HKDGNARGTTLL------------CLDC---ILPPIHPTEKPVGLFLQ-D
IEK----IGGI-DTVPVGLVETGVLKHG--M-VINFAPVNV-ITEVKYVEMHHEL-----
----SE--ALPWDKVGFD-VK-----KVSVKDVHCGNVAGDSKND-P-PM---GETAGFT
VQVITL-HS---GQTGAGYEPVLD--------------------CHT-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKENTHINTV-AIGHV-
DSGKST-T--TGHLIYKCG-GIHKR--TIEKFEKEA-AEMGKGSCKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KFYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLT-VAA-GVGEFEA------------------------------
------------------EHALLA-YTLGAKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VITYIKKI-GYNP--ETVAFVPISGWNGDNMRE-PS-----ANM-PW
-FKGW-KVT-RKD-----------------------------------------------
------------GNA

PF03144 // ENSGT00910000144046_0_Domain_0 (436, 518)

SGARLETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALLGDNVGFN-VK-----NVSVKDVHHGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVITLNHP---DQISAGDAPVLD--------------------GHMAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--DDAAIIDMVPGKPMCVE-----SFSDYPPVSH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGTGKVT
QSAQKAQKPK--------------------------------------------------
----------------------------------------

--------------------------------------------KENTHN

PF00009 // ENSGT00910000144046_0_Domain_0 (51, 345)

NI---IGYI-
DSGKSI-T--MGHLAYKCR-GSNNF--S------EA--V---GMGKFSF---KYN----M
Y------------HQ-KYLPVE-----SETI--K-YHA--SIRHP-----GHRDFIKNTI
A----S-TFKAD-YAALI-VAA-GVGEFKAVI---------SKNGQT-------------
-----------------HEH-TLC-ETLGVKQLMVTIN--------RVNS-----TEQQK
R----YEEIVKK-VSTYIKKI-GYNP--ETVAFMPISGWNGDNMLE-PN-----ANR-PW
-VKRK-KVT-HKDSNTSGTTFL-----------KDQDC---ILPLTCPTKKFLHLPLA-D
VYK----ICGI-GTIPMG--QVVIGNYS--V-VVPFAPVNV-TAEVKSVTMHHEALS---
-KALSE--ALPQYNIGFN-VN-----NISVKDVCYGNMASDSYND-P-AM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 656)

-E-AAGFM
AQVIILNHT----SISAGSAPLLK--------------------CHITHTTCKL-AELKE
KIDHHSGK-KLES-SKFLKS--GDAAINDMVPGKPLCVE-----SSSDSP-LGC-FSVCS
----------------------------------------C--CVIKAVDKKAAGVGKVS
KSSQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TTEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--ITDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------------------------------E-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPS--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 533)

VAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-ATGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSDK-KLEDGPKFLKS--GDAAIVDIVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-A--TGHLIYKCG-GIDKR--TIEKSEQEA-AEMGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDDP-----GHRDFNKNMI
T----G-TAQAD-CAVLI-VAA-GVGEFEASI---------SKNGR--------------
------------------------------------------------------------
----------------------------PEIAFVTVSGSNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTMLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYQ----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRGETGILKPG--M-VVTFAPVNV-TTEVKSVKMHHEAL----
----NE--ALPGDNVGFS-VK-----NVSVKDDRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIAGKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVCD
MRQT-VV---------------------------------V--GVIKAVDKKAAGAGKVT
KSVQKAQKVK--------------------------------------------------
----------------------------------------

------------------------------------------NGKEKLHTNPV-ISGHV-
DSRKST-T--TGRLSSTCG-DSNRR--TAKKFEKEA-AEMGKGCFTCAW---VL-----D
ER-KAEPECGI--TI-SISLWS-----LETS--KYYVT--TSNVS-----GHRDFIKHVI
P----G-TSQVA-CAVLV-VA--AAGEFEAGS---------CKNRQT-------------
-----------------HEHALLA-GTLGVKQLVVGVN--------KVDSTEPPYS--Q-
--------IVKE-VSTYVKKI-GYNP--DTVAFVPISDWNGYKLLE-LC-----ANI-PW
-FKGW-KVT-HDDSHASGTTLL-----------E-LDR---ILPPTRPTDKPSRLPLQ--
-------IAGI-ATDPG

PF03144 // ENSGT00910000144046_0_Domain_0 (438, 519)

GHVETGVLKPG--M-MGTFVPFSV-TTEVKSIEIHHEAL----
----SD--ALPGDNLGLN-VK-----NMSVKDVHHGDV

ENSGT00910000144046_0_Linker_0_1 (519, 541)

AGDSKDD-P-PM---G-HSGT-

PF03143 // ENSGT00910000144046_0_Domain_1 (541, 709)

TQVMDLNHP---GQLSAGY-PVLD--------------------CHPAHLACKL-VELKE
KIHHCFGK-KLEEGPEFWES--GNTAIVDMVPGKPMGVE-----SSSDYPPPGC-FTVCE
MRQT-VA---------------------------------V--GVIRTVDKKAAGASKVT
KSSQKTQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VTGHV-
DSDKST-T--TGHLNYKCG-SINKR--TTEKFEKEA-AEMGKGSFKEAW---VL-----D
KL-KAERERGI--TI-DTSLWK-----FETS--KCYVT--IIDRL-----SHRDFTKNMI
T----G-TSQAD-CAVLI-VAA-SVGEFE-------------------------------
------------------EHALLA-YTLGVKQPIVGVN--------KMDSTEPPYS--QK
R----YEEIVK-------EKT-GYNP--DTEAFVPISGWNGDNMLE-P------------
-----------SDGNTSGTMLL-----------EALDY---ILPQTHPTNKPLCLPLQ-D
---------------------TGVLKSG--M-VVIFAPVNI-KTEVKSVEMHQEAL----
----SE--TLSGDNVGFN-VK-----NVSVKDVHHGNDAGDSKDD-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHTASKF-AELKE
KMDRHVGK-KLEDGPNFLNS--GDAANVDMVPGKPVCVE-----CFSDYPPLGR-VAVHD
MRQT-VA---------------------------------V--DVIKAVNKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKIHINIV-VIGHI-
DLGKST-I--AGHLIYKCG-GIDKR--TIKKFEKEA-AEMGKGSFNYAW---VL-----D
KL-KAECERGI--AI-DISLWK-----SETS--KYYVI--IIDTP-----GHGDFIRNMI
T---------AD-CSVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIIKE-VSTYIKKI-GYNP--ETVAFVPISGWNGDNMLE-PS-----ASM-PW
-FKVW-KVT-CKNGNASGTALL-----------EALDC---ILPPTRPTDKPLHLPLE-D
VYR----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTAPVGRVETGILKPG--M-VVTFAPVNV-ITEVKSVEMHHEAL----
----SE--ALPGDNAGFN-VK-----HVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

SDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-PAGFT
AQLIILNHS---GQISAGYAPVLD--------------------CHIAHIAWKF-AELKE
KIDRCSGK-KLEDGPKFSKS--SHAAIVDMVPRKPMCVE-----SFSDYPPLGR-FAVCH
MRWT-VA---------------------------------V--GVTKAVDKKAAGAGKVT
KSLRKLRRLN--------------------------------------------------
----------------------------------------

------------------------------------------KRERKTHINII-FIEHI-
-----------DLLIYKRA-WINRR--ITKKFKQAV--EMGKGSFKYTY---VFN-----
---------

PF00009 // ENSGT00910000144046_0_Domain_0 (130, 345)

KYAMTI-NTSLWK-----YETS--DHYVV--IIDAL-----GQRD-IKFMI
I----G-TSQAD-CAVLM-VSV-GST----DI---------SKNRQT-------------
-----------------HEHSLPA-YTLNVKQLTVGVT---------KDSTEPPYT--QK
R----CEKIING-VSTCIKKI-GYNP---DITFVPISGWNGSNTLE-PS-----ANM-PW
-FEGW-KFT-HKDDNFSGTKWL-----------EALDC---ILSPIHPTDKPYL-LLQ-N
VDK----IGGF-DTVPV----TGVLKHG--M-VVTLLQ-----TMSQSAEMQHEAL----
----SE--ALSGVNVGFN-VK-----NVSVKDVQHGNLEDNRKNE-P-PV---E-A

PF03143 // ENSGT00910000144046_0_Domain_1 (537, 709)

VGFP
AQVIFLNHS---GQVSTGYPPALE--------------------CQTAHIVCKF-AELKR
KIDCCSGK-KMKDDSKFLKS--VDAAIVDMVLGKPMCVE-----NLSDSPFLG--FSVHE
MRQT-ID---------------------------------M--GAIKAVDRKSIGTGHIS
KYAQEDQKAN--------------------------------------------------
----------------------------------------

-------------------------------------------MRKDKTINIV-VIAHV-
DSGKSI-A--TGQLSYRYF-FIDKQ--AIEKFEKEA-AEMGKGSVQAAW---VL-----D
KW-KTECEGGL--TI-EISLWK-----CEIS--QCYMT--IIPAP-----RHRDVIKN--
---------QAD-RAALL-LAA-GVGEFEAGI---------SKNGT--------------
------------------EHALLA-YTLGVKQLIVGVN--------KMDSTEPLYS--RQ
R----YEEIVKE-VS-----T-GYTP--DTVAVVPISG-NGDSMLE-PS-----AHL-SW
-FKGW-KVT-CKDGDARGTTLL-----------EALDR---ILP-TRPTDKPLRLPLQ-D
VYT----IGGL-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--I-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALFGDHVGFN-VK-----NVSVKGVHYSNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---G-ISAGYTPVLD--------------------HHSAHIACKF-AEL-E
KIDHRSGK-KLEEDPKLLKS--GDAAIIDMVPGKPRCVE-----SFSDCPPLSR-FAV-D
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
QSAQKVQAT---------------------------------------------------
----------------------------------------

------------------------------------------------------------
----------------------------------REAAETAKGSSRHAW---VS-----D
TL-KAEFLS-MVTTT-DSSLRK------------------------------SGTSEDTI
V----G-TPQAA-CAVLT-AGA-GVREFEAI----------SKNGQT-------------
-----------------CEHALWL-IY----WLSVSLN--------KMDSTELPYS--QK
R----QQEIVKE-VRSHIKKT-GYNT---ICAY----FWLEQRERVEPS-----ATT-PW
-FRNE--VT-HKDGSATGSTLL-----------EALDC---TLL---PADKPLCSPLH-D
AYK----VGGI-GTVPVGQMGTGVLTTG--KVVVNFAPLSV-TTDFKSVELHHEL-----
----SG--ALPGD-VDLN-VE-----NMSVKDVHSGKAAGDSKN--P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 661)

PT---E-AAGFT
AQVIILNHP---QQISAGYAPGLD--------------------CHSSHCF-------PE
GEDSCSGK-KLDNSFQFLRS--GDAASVDKVPGKPACVV-----SFSDL-----------
MRHI-VA---------------------------------V--AMIKAVHKKAARAGKTM
KSIQKVQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKKKT

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 138)

HINIV--IRHV-
DSGKFT-T--TGLLIYKCG-GIDKR--TTEKFEKEA-AEMGKGSFKYTW---DL-----D
KL-KAEREHGI--TT-DIFL---------------------------------DFIKNMI
T----S-TSQAD-CAVLI-VAA-GVGRFEAGI---------SKNGQT-------------
-----------------REHPLLA-YT-------------------------------QK
R----YKE-IKE-VSTYIKKI-GYNP--DTVAFAPISGWNGDNMLE-PS-----ANM-PW
-FTGW-KVT-RKDADASGTTLL-----------EALDC---ILPPTPPTDKPLRLPLQ-D
VYK----IGGI-GTFPEGRVETGVLRPG--M-VVTFAPVNV-TTEVKCVEMHHEAL----
----SE--ALPGNNVGFN-VK-----NVSVKDVHRGNVAGDSKND-P-PM----------
--

PF03143 // ENSGT00910000144046_0_Domain_1 (543, 708)

VIILNHP---GQISAGCAPVLD--------------------YHTAHIACKF-AELKE
KIDHRSGK-KLEDG-------------------KPMCVD-----SFSDYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIEAMDKKAAGAGQVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIKKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSKAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PC
-FKGW-KLT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-STEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNMAGDSKNE-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGST
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHRSGK-KLEDGPKFLKS--GYAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGNE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TSHLIYKCG-GIDKR--TMEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAKCERGT--TI-DISLWT-----FETS--KYHVT--ILDAP-----GHRDFIKNMI
T----G-TSQTD-SAVLI-VAA-GVGEFEAGI---------SNNGQT-------------
-----------------HEHALLA-YTLGVKQLIVDVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKGGNASGTTLL-----------EALDC---ILPPTYPTDKPLWLPLQ-N
VYK----IGGI-KW--------RQRKPG--M-VVTFAPVNV-RIEVKSVEMHHEAV----
----SE--ALPGDSVGFN-VK-----NVSVKDVWHGSVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 658)

-AAGFT
AQVIILNHP---GQISAGCAPVLD--------------------CPTPHNACRF-AKLKE
KIDRWSGK-KLEEGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDSPPLSR-FAV--
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AELGKGSFKYTW---LL-----D
KL-KAEYECGI--TI-DIFLWK-----FETS--KYYMT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-AVDEFKAGI---------SKTGQT-------------
-----------------SEHALLA-YMLGVKQLIVGVN--------KMDSIEPPYS--QK
I----YEEIVKE-VSAYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVI-SKDSNANGTTLL-----------EALDC---ILPPTRPTDKPLQLPLQ-D
VYK----IGGI-STVPMGRVETGVLKPA--I-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NMSVKDVRHENVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIDCKI-TELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FTVCD
MRQT-VA---------------------------------V--GVIKAVNKKAAGAGKVA
----------------KSAQKLR---------GLNEYHP---------------------
----------------------------------------

------------------------------------------MAKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 404)

TYVNIV-VIGHI-
DSGKST-T--TGHLIYKCG-GINKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEGERGV--TI-NISLGK-----LETS--KYYVT--IIDAP-----GHRDFIKNTI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLTVGIN--------KMDST---------
E----YEEIVKE-VSTYVKKI-GYNP--DTVAFVPISGWNGDNMLG-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKALHLPLQ-D
VYK----IGGI-GTVPVDRVETGVLKPG--M-VVTFAPVNI-TTEVKSVEMHHEAL----
----SE--ALSGDNVGFN-VK-----NVSVKDVRHGNVAGDSKND-P-SM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 657)

-TAGFT
AQVIILNYP---GQISAGYTPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FACSR
CLTM-AT---------------------------------F--AFQSHVSPYHLRN----
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKIHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEREHGI--AI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAA-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------QEHALLA-YTLGEKQLIVGVN--------KMDSTESPCS--QK
R----YEEIIKE-VSTYIKKI-GYNP--GTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-LKDGDAIGSTLL-----------EALDC---ILPPTCPTAKPLHLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHHGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACNF-AELKE
KIDRRSGK-KLEDGSKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-F----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------FSEEFTNINLL-SIQLF-
SCHNYN-T--IGHLPYKCG-GINKR--TMEIFEKKA-AEMGKSSFWYPW---VL-----D
KP-KAECERGI--TM-DISLWK-----FETS--KYYGT--ITDAP-----GHRAFIKNMV
T----G-TSQAY-CAVLI-SAAVCCCEFERSI---------SKNEQS-------------
-----------------HEHAILP-YTLGVKQLTVGVN--------KMDSTEPPDN--QK
R----YEEIIKV-GSTYIKKM-GYNP--NTVALVPISGWNGDNMPE-PT-----VNM-PW
-LKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTCPPDK-LCLPLQ-D
IYR----IGG--

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GAVPVGRMETGVLKPG--M-VVTFAPVNV-TTEAKSVEMHHEAL----
----SE--ALAGNNVSFN-VK-----KMSA-KVHRGN

ENSGT00910000144046_0_Linker_0_1 (518, 533)

VAGDRKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 721)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLH--------------------CHTAH--CKF-DELKE
KIDHHSGK-KLEDGPKFLRS--GDAAIVEMVPGKPVCVE-----SLSDYPPLGR------
-----VA---------------------------------V--GVIKAVDKKTAGAGMVT
KSSQKAQKPK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 664)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FA--V
R-DM-S----------------------------------------FFPQSP-----RRN
HLLSCPEGSSF-------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEIEA------------------------------
------------------EPALLA-YTLGKR-----------------------------
-----YEEIVKE-VSTYIKKI----------AFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

----------------------------------MGE---NFCNLEKTHINTV-IIGHI-
DSGKST-T--TGHLIYKRS-GVDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDLIKNMI
T----G-TSQAD-CAVLI-VAA-GFGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--HK
R----YEEIVKE-VSTYIKKI-GYNT--DTVAFVPVSGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLCLPLQ-D
VYK----IGGT

PF03144 // ENSGT00910000144046_0_Domain_0 (432, 518)

-GTVPT-----GVLKPG--M-VVTFAPVNV-ATEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KTDRHSGK-KLEDGPKFLKS--GDAAIVDMVPGKPVCVE-----SFSDYPPLGR-FAVHD
IRQT-VA---------------------------------V--GVIKAVGKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------W---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLM-VAA-GVGEFETGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----EEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-LKGW-KAT-RKDGNASGTMLL-----------------------------------E-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--V-VVTFAPVNV-TTKVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-TADFT
AQVIILNHP---GQISTGYAPILD--------------------CHAAHIACKF-AELKE
KIDRSSGK-KLEDGPKFLKS--GDAAIVDMVPGKPI-VE-----SFSDYPPLGH-FTVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGGGKVT
KSAQTAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MVKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 396)

KTHINTV-VIGHI-
DSGKSM-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KDEHEPGI--SI-DISLWK-----FKTS--KYYVT--ITDAP-----GHREVIKNMI
T----G-TSQAD-CAILI-VAA-GVGEFETGI---------FKNGQT-------------
-----------------REHALLV-Y-----------------------------T--QK
R----YKEIVKE-VSTYIKKI-SYNP--DTVAFVPISGWNGGNMLE-PG-----SNM-PW
-FKGW-KVT-GKDGNDSGTTLL-----------EALDY---IRPPTHPTDKPLHLPLQ-D
IYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFVPVNV-TTEVKSVEMHHEAL----
----SE--SLPGDNVGFN-VK-----NISAKDVRHGNVAGVSKND-P-PM----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIL-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKQ--TIEKFEKEA-AKMGNGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--TIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------PKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTESPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGITLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETDVLKLG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGNNVGFN-VK-----NVSVKDVRHGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
TQVIILNHP---DQISTGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPMGH-FAVRD
MRQT-VA---------------------------------V--GVIKAVD----------
--KKAAG----AGKVIKSAQKAQ---------KAK-------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-P--TGHLIYKYD-GINKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VTA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 514)

GTVPVGRVETGVFKPG--M-VVTFAPVNV-TTEVKSVEVHHEAL----
----SK--ALPGDNVGFN-VK-----NVSVKDV

ENSGT00910000144046_0_Linker_0_1 (514, 529)

HRDKVGGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 718)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SYSDYPPLGG-FAVHD
MRQT-VA---------------------------------V--GVIKA---------VD-
--KKAAG----AGKVTRSAQKAK-------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANI-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-G

PF03144 // ENSGT00910000144046_0_Domain_0 (434, 518)

TAPVGQVETGVLKPG--M-VVTFAPVNV-TTKVKSVKMQHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-LM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 594)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF------
-------------------S--GDAAIVDMVLGKPMCVE-----SFSDYPPLGR-FAVRD
TRQT-VA---------------------------------V--GVIKAVDKKVAGAGKVT
KSVQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MEKA

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 348)

KPHINIV-VIGHA-
GSGKST-I--AGHLIYKCG-GISKR--TIENFGKKA-AEVRKGSLKYPW---VF-----D
KL-KAEHKHGV--TI-DISLWK-----FATS--NYYVT--IIDTP-----GHRDFIKNTI
I----D-TSQAD-CAVLI-VAA-GVGEFEASL---------SKNGQT-------------
-----------------PEACLLA-YTLGGRQLIVSVN--------KMDSAEPPYS--LK
R----YEEIVKA-VSAYIKKI-GYNP--DTVVFVPISGWNGDNMLE-LN-----ANM-PS
-FKGW-KVT-RKDGNASGTTML-----------E--------------------------
---------------------IGVLKPG--V-VVAFAPVNV-ITEMKSIEMRHGVL----
----SE--ALPGDNVGFN-VK-----NVSVKDVCHGNVAGDSKSD-P-SM---E-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 701)

AAGFL
VQVLILNHP---GHVSAGYALVLH--------------------RHTAHSACKF-AELKE
KIDRH--------GPELLQP--VEAAIIDMVPDKPMCM----------------------
-----VA---------------------------------V--RVIKAVDKKATGAGKVT
KSAQKTLKAKR--ILSPI-PVTP--SSSVVEGRSQN-----CL--CQLAI----------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTLINIS-VIGHL-
DSGKSI-T--TGHLIYKCG-RVNKR--TIENFEKEA-AGVGKGSFKYAY---IL-----D
KLK-AE-----MRTI-DISLWK-----FQTR---------------------KDFIQNMI
T----D-IFQAD-CAVLI-VAA-GNGEFEAGV---------SKNGQT-------------
-----------------HEHALLA-YTLGLNLLIVGVN--------KMDSTEPTYS--QK
R----YKGIIKE-VSTYIKKI-GYNL--NTVAFVPNSDWNGDNVLE-PS-----AK---W
-L-KW-KVT-HKDGNVIGTTLL-----------KALDC---ILPSTPPTDKPFCLPLQ-D
IYK----IGGI-GTVPVGQMQTSVLKPN--I-VVTFAPVTV-TNEVKCIKMHHKAL----
----SE--ALSGNNVGFN-VS-----NISVKDVRSGIVAGGSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PT---E-AAGFT
AQVIILNHP---G-ISAGYAPVLD--------------------WHTVHIALKF-VELKK
KTDCRSGK-KLENGPKFLKS--GDAAIADTVPGKPVHVE-----SFSDSPPLGH-FAVHD
MRDC--S---------------------------------A--GVIKAVAKKAAGAGKVI
ESAQKVRKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHINIA-VIGPI-
DSGKCT-T--PGHLIYKCG-GIDKR--TIEKFEKEA-AGIGKDSFRYAW---VL-----D
KL-KAERECGI--TV-DISLWK-----FKTS--KCYVT--ITDAP-----GHADFLKNMI
S----G-TSQAD-CAVLI-VAA-G-GEFEACL---------SKNGQT-------------
-----------------HEHALLS-YTPGVEQLIVGVH--------KMDSTELSYS--RK
R----YEEIIKE-VSTYIKKI-GYNL--SMLAFVPISSWNGDNMQE-PS-----ANM-SQ
-FKGW-TVT-RKDGKASGTTLP-----------EALDG---ILPLTCPADKPSCLPLQ-D
VYR----IGGI-GAVPVGRVETAVLKPG--M-LVTFAPVSV-TAEVKCVEMHPEAL----
----RE--ALPGDNVVFN-VK-----YISVKGVRRGSVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGLR
AQVIVLSHP---GQ-----APVLD--------------------FHTVHIACKF-AEPKE
KMGPSSS-----FFPEFLKS--GDAAIVDMVPGKPMCVE-----SFSH-PPLGR-SAVCD
TRQT-VA---------------------------------V--GIIKAVDKKVARAGKAT
KS--AQKAPKG-------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 316)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VXXXXXXX-XXXX--XXXXXXXXXXXXXXXXXX-XX-----XXX---
--XX---XX-XXXXXXXXXXXX-----------XXXXX---XXXXXXXXXX--XXRLV-N
DNN----AS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------D

PF03143 // ENSGT00910000144046_0_Domain_1 (614, 709)

SPKFLKY--GDVSIIDMVPGKPMCVE-----SFSDYTPLGH-FTIGD
TRQS-VA---------------------------------V--GVIKVVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-A--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----LETS--KYYMT--IIDAP-----GHVDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVDEFEA------------------------------
------------------EHALLA-YTLGVKQLIVGVN--------KMDSTEPPYN--QK
R----DEEIVKE-VSTYIKKI-GYNP--HTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTMLL-----------EVLDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLQPS--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 703)

-AAGFT
AQVIILNHA---GQISAGYAPILD--------------------CHMANIACKF-AELKK
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------VGVGVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-I--TGHLIYKCS-SIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KR-KAEREHGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMV
T----G-TSQAD-CAVLI-VAA-GVGEFEA------------------------------
------------------EHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGNNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTMLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GSVPVGRVETGVLKPS--M-VVTFAPVNV-TTEEKSVKMHHEAL----
----GE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GRISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRHT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
NSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------K-N

PF03143 // ENSGT00910000144046_0_Domain_1 (611, 709)

LEDDPKFLRS--GDAAIVDMAPGKPMCAE-----SFSDYPPLGR-FAVCD
MRQA-VA---------------------------------V--SVIKAVDKKAAGTGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---GW-KVT-HKDGNASGTTLL-----------ETLDC---IWP-THPTDKPLHLPLQ-D
VYK----IGGI-DTVPVG

PF03144 // ENSGT00910000144046_0_Domain_0 (439, 501)

KP-------A--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----GE--VLPGDNVGFN-V

ENSGT00910000144046_0_Linker_0_1 (501, 524)

K-----HVSVK--CRGNVADDSK

PF03143 // ENSGT00910000144046_0_Domain_1 (524, 710)

ND-P-PM---E------
AQVIILNHP---GQISAGYASVLD--------------------CHTALIVAS----LLE
GEDCRSRK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIEHI-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DSSLWK-----FETN--KYYVT--IIAAP-----RHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GAGEFQAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTHPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 661)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
M-----S---------------------------------C--SYL------GN----LF
EE----------------------------------------------------------
----------------------------------------

-------------------------------------------------

PF00009 // ENSGT00910000144046_0_Domain_0 (50, 382)

INIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFRYAW---VL-----D
KL-KAERERGI--TI-NISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGVN--------KMDSTEPLYS--QK
R----YEEIVKE-VSTYIKKI-G-------------------------------------
--------------YNHGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPT-----GVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---CQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGL-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKATGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AELGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DSSLWK-----FETS--RYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-A------TVAFVPISGWNGDNMLE-PS-----------
-------VT-RKDGNASGTMLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPT-----GVLKPG--M-VVTFAPVNV-TTEVKPVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRHGSVAGDSIND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILKHP---RQISAGYAPVLD--------------------CHTAHIACKF-AEPKE
KIDCRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------SALIV--AA-GVGEFEA----GI-----FKNGQT-------------
-----------------REHALL-----AYTQHDVGVN------K--MDSTELPCS--QK
R----DRDIVKV-APTF-KKM-ATTLTTWLYTFVPISGQNGDNIL---E-----PSA-H-
-IPGI-MLL------G------------------ALDC---ILPPACPIDKPLYLPFQ-D
VLS----LW----AV-E----TGVLKPS--I-MVSFAPVNV-KTEVK-VEMHQEAL----
----SE--ALPGDNVGFG-IK-----NVSVKDVHHSNAVGDSKND-P-PCS

PF03143 // ENSGT00910000144046_0_Domain_1 (532, 710)

ARE-AADCT
AQVIILNHP---GQISA-HAPTLD--------------------CHTAHIAFKF-AKMKE
IIDHHSGK-MLEDGPKVLKF--GDAAIVDMVPSKPMCVE-----SF--YLPLGH-FAVHD
RKQT-VA---------------------------------V--GVIKAVDKKAAGTGKVT
KSAQEAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----------
------KVT-HKDGNASGTMLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPT-----GVLKPG--M-LVRSAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDSVGFN-VK-----NVSVKDVRHGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISSGYAPVLD--------------------CHTAHIACKF-AELKE
KIDGCSGK-KLEDGPKFLKS--GDAAIIDMVPGKPMCVE-----SFSDYPPLGC-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAKYYR-----------------------------------------------
----------------------------------------

------------------------------------------SGKGK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 345)

EHINII-FTTGR-
VLGEST-I--TGHLMYKRG-GIDER--TIKNSENEV--A---EMRKDAL---SFS----S
AL-KMKAEHEHGITT-ATSLWK-----SETS--KYYVA--TSDDP-----GHRNFIKNLI
T----S-KSQAS-HAVLI-AST-GVGEHEAGF---------SKNGQT-------------
-----------------HEHVLLV-YTLAVKLLI---------VGVKMDSTEPPCSQERH
K----------KSAPTL-RKL-A----TVPVALVPISGWNGDNMLE-PS-----ANM-P-
-VQGM-ESH-PQDGNAGGTMLL-----------EARDC---ILPP-TPTDKFLHLPLQ-D
VHD----ISGI-GTVP-----VGQAESG--I-VVTFAPIRI-TTELA-LLMDHGAL----
----SE--ALPGDNVGFK-AE-----KVSVKDVHHGKVNGISKND-R-PM---E-AAGS

PF03143 // ENSGT00910000144046_0_Domain_1 (540, 709)

T
AQGIILNHL---GQISDGS-VTVD--------------------CHTAHTACKF-AALKE
KLDCSSGK-KLEDGPRFLKS--GV-----WLPGKPICVE-----SFPDYPPLGC-VAVHD
VRQT-V----------------------------------A--GVIKAVGKQAARAGQVT
SSTEKAQKVK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------E-------------C-------------
-----------------H

PF00009 // ENSGT00910000144046_0_Domain_0 (259, 411)

EHALLA-FTLDVKQLIVGVN--------KMDSTEPPHS---Q
R----EEEIVKD-VSTCIKEI-GYNF--DTGAFIAVSGWNGNNM-----------LE-LW
-FKGK--SP-IKIGNASGTMLL-----------ESQDC---FL----PLSRPSDMPLH-D
VHK----IGGT-GTVPMGQMHGGHLS------------FSV-TTEVKSAEMHYEAL----
----RE--AFPVDNLDF----------VSVKGIHHDNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AHVIILNHP---GQINARCAPVLA--------------------CLTAHI-AKF-AELK-
KIDHYSAK-KLEDGLKFLKS--SDSAIVGMVSGKPMCVE-----SFSDYPPLDH-FAVCD
MRQA-V-------------------------------------GVIKAVDKKAAGAGKVT
KSAQKAQKAE--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--LQTDYEHGV--TI-DSSLKH-----PVT----------ITVVS----

PF00009 // ENSGT00910000144046_0_Domain_0 (170, 404)

-GHNNFIKRRI
---------IAD-CAVLI-VPA-GVGEFEK--------------GQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KTDSTEPPYS--QK
R----YEEIVK-------EKI-GYNP--DTVAFVPFSGCNGDNMLE-PS-----ANT-PW
-FKGW-KVN-CEDCNANGTTLL-----------EALDC---ILPPTHPSDQPS---LQ-D
VYK----IGGI-GTT-------SVFKPD--M-AVTFAAGNV-TTVVQCVEMYHEAL----
----SE--ALPGDNVGFD-VK-----NVSVKDVGQGDVAGDSKND-P-SV---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
TQGIILNHP---GQISAGYAPVLD--------------------GHTAHIACRF-TECK-
KTDRRSGK-TLEDGPKFLKS--GDAAIVNVVHGKPMCVE-----SFCDYPPPGH-FAVRD
MRQT-TG---------------------------------V--GVVKAVDEKVAGAGRDT
KSSQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 624)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GD------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------KVT-RKDG-AGGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----NFSDYPPLD-------
IKQM-VA---------------------------------V--GVIKAVDKKTA--GKVT
KSTQKAQRAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKENT

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 404)

HINI--VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DSSLWK-----FETS--KYYVT--IIEAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-SYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLCLPLQ-D
VYK----IGGI-GTVPVGRVETDVLKPD--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPEDNVGVN-VK-----NVSVKDVRRGNMAGDRKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVPD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

MGGGDGGGTGAGWRWRGVNWESGVVCWLRPFPRGWGRTIYKRRGPRERSFSQR--VCRQ-
DTG-VV-K--AIAKSYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MAK

PF00009 // ENSGT00910000144046_0_Domain_0 (46, 406)

EKTQS-DI-IIGHV-
DSGKSN-T--AGHL--------ITG--GEV----KKAAAEMGGSFKSAW---VL-----D
KL-KAEREVGSGITM-ESSLWK-----GTG---KYHVT--IVDAL-----GHRAFI----
-----G-TSQAD-CAALV-A-A-GVGEFE-VI---------SKTGQT-------------
-----------------HAHALLT-YTLGAKQLIVGVN--------KMDSTEPLYS--QQ
E------ELVKE-VGNYIFKK-GYT---DTVTFVPITGWNGDV-LK-PS-----APM-PW
-LKGW-EVT-PKDGNARGTTML-----------KALDC---ILPPTRPTDKPCLPL----
-----------------GT--------V--E-VVTFAPV-H-VTQVKSVEIYHEAL----
----SE--ALPR------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 420)

KTHINIV-VIGHM-
DSGKST-T--TGHLIYKCG-GIDKR--TIEEFEKEA-AEMGKGSFKYAW---VL-----G
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDVP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YKEIVEE-VSTYIKKI-GYNP--DTVAFVPISGWNGDMLE---------------
--PRW-KVT-RKDGNASGTTL-----------------------------------LE-D
VYK----IGGI-GTVPVGQVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E-A----
--

PF03143 // ENSGT00910000144046_0_Domain_1 (543, 709)

VISLNHP---GQISAGYAPVLY--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVCD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MVR-PS-----TPM-TW
-SKSL-KTT-QKEGSASGTTAL-----------ETLGY---IL-PICPTDKPLFIPDK-S
I---------STGSAPVNQIEMGVLTSG--I--LTIVPVSV-KTIVKTVEIHHEAP----
----NE--VLSGDNMGFN-VK-----STSANSFYCGSIIGDGNSDL-------M-D

PF03143 // ENSGT00910000144046_0_Domain_1 (537, 710)

TGFT
AQVLILNHL----QVSAGYAPVLD--------------------CHTAHT--EF-TVLTE
KTDHYFGK-NLKDGPKFVKYDVNDDAIIDMIPGKPMGVE-----SCLGCPPLGQ-LVVHD
RQT--CA---------------------------------V--SVLKAVGKKAARTGKFT
MSVQKTKC----------------------------------------------------
----------------------------------------

-------------------------------MGE------NFCNLEKTHINTV-IIGHV-
ESGKST-T--TGHLIYKRG-GVDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--ILDAP-----GHRDLIKNVI
T----G-TPQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--HK
R----YEEIVKE-VSTYIKKI-GYNT--DTVAFVPVSGWNGDNTLE-PS-----------
------KVT-HKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLCLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVP-----TGVLKPG--M-VVTFAPVNV-ATEVKSVEMHHEAL----
----SE--ALPGNNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KTDHHSGK-KLEDGPKFLKS--GEAAIVDMVPGKPVCVE-----SFSDYPPLGR-FAVHD
IRQT-VA---------------------------------V--GVIKAVDKNAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

---------------------------------------IGKEK---THINIV-IVGHV-
DSGKST-T--TGHLIDKCG-GIDKR--TIEKFEK--------GSFKDTW---VL-----D
KL-KAEQERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
P----G-TSQAA-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGMKQLMVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KIT-RKDGNTSGATLP-----------EALDC---NLPPTRPTDKPLRLPLQ-D
VSR----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPN--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVTVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKHG-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFA
AQVIILDHP---GQISAGDAPMLD--------------------CHTAHIACKF-AELKE
KMDRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDCPPLSH-FTIRD
MRQA-VA---------------------------------V--GVIKAVDKKADGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------LGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEHERGI--TI-DISLWK-----FETS--KYYVI--VTDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLARR-----------------------------
D----NEEIVKE-VSTYINKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-SW
-FKGW-KVT-HKDGNASGTTLL-----------EALDC---ILPPTCPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMYVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

----------------------------------------MGKK--

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 206)

-THINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----E
KL-KAERERGI--TT-DISLWK-----SETS--KYYVT--ITDAP-----GHRDFVKNMI
T----G-TSQAD-CAVLI-AAA-GVGEFGV------------------------------
------------------------------------------------------------
-----------------------------------ISPRNGDNMLE-PS-----ANP-PW
-FKGW-KVT-RKGGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GAVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIVLDHP---GQTSVGYAPVLD--------------------CHTAHIACKFAQ--LK
KIDHRSGK-NLQDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVCD
MRQT-VA---------------------------------V--GVIKAVDKKADGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINVI-VIGYV-
DSGKST-T--TGHPIYKCG-GINNR--TIEKFEKEA-AEMEKGSFKYAS----L-----G
QT-EAEHERGI--TT-NISLWK-----FETS--MCYVT--IIDDS-----EHEDFIKNMI
T----G-TSQAH-CAVLI-VAA-GVGEFEAGI---------SENGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPSYS--QK
R----YEEIVKE-VSTSIKKI-GRNP--DTVAFVPISGWKGDNMLE-P-----------R
-FKGW-KFT-HMDGNASGIALL-----------EALDC---ILPPTHATD-KPHLPLQ-D
VYK----IGDI-GTVPVGCVETGVLKPG--M-VVTFAPVSE-TTEV--VEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVEDIHHGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNQP---GQIDAGYAPVLD--------------------CDTAHVACKF-AELRK
K-DRHYGK-KLEDGLKFLKC--GDAAIVDMVSGKPMCVK-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

PF00009 // ENSGT00910000144046_0_Domain_0 (176, 345)

IKNVI
T----G-TSQVD-CAVLI-VAA-GVGEFEASI---------SKNGQI-------------
-----------------SEHALLA-YTLDVKQLIVGVN--------KMDSTEPPCS--QK
R----YEEIVKE-VSTYIKKI-GYNP--NTVAFVPISGWNDDNMLE-PT-----ANV-PW
-FKGW-KVT-CKDGILP--------------------------P-SGPNDKPLRLPLQ-D
VHK----IDGI-GTVPGGQVKTSVLKPG--T-VVTFAAVDV-TTEIKSVEMHQEALS---
---EIN--FIPGNNMGFN-IK-----NVSVKDVRCGNIAGDSKNG-P-PR--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-K-AAGIT
AQVIILNHP---GQIIAGYTPELD--------------------CHMAHTACKF-AVLKE
KIDHHSGK-KLEDGSKFLKS--VDAAIIDMVPGNLVCIE-----SFSDYPPLGH-FAVCD
MRQT-VA---------------------------------V--GVIKAVDQKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------AGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHVNI--IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AKMGKASFKNAW---IL-----D
KL-KTKHEPGI--TI-DISLWT-----FGTS--KYYVT--IIDAP-----GHRDFIKNMI
T----------S-CAVLI-VAA-GAGEFEAGI---------SKNGQI-------------
-----------------REHALLA-YTLGMKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYVKKI-GYNP--DTVAFVPISGWNGDNILE-PS-----ANM-PQ
-FKGW-EVT-HKDGNASGTILL-----------EALDC---IQTPTHPTDKPLHLPLQ-D
VYK----IGGI-ATVPVGKLETGVLKPG--M-VVTFAPVNA-TTAVKSVEMHHEAL----
----SK--ALPGDNVGFK-VK-----NVSVKDVCRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AVGFA
AQMIILKHP---AQISSGY----D--------------------CDTAHVACKF-TELKE
KINHHSGK-KLEDGPKFLQS--GDAAIIDMVPGKPMCVK-----SFSEYTRLGH-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKATGAGKVT
NSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 312)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFK-EA-AEMGKGSFKYSW---VL-----D
KLKA--EERGI--TL-DISLWK-----FETS--KYYVT--VIDAL-----GHRDFIKHVI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SENGQT-------------
-----------------CEHALLA-YTLGVKQPIVGVN--------KMDPTKHPTA--RR
D----KRN--YQ-GSQYLYQE-NWLP--PDTLACASFRWNGGNMLE-PS-----PNM-LW
-FKGW-KVT-RKDGKANGTTLL-----------EALNC---ILPPTHP-----------N
VYK----IGGI-GTVPVGYVETGVLKPG--R-MVTLPQ----------SIMHHEAL----
----RD--ALLGDNVGFN-VN-----NVSVKDVRRGYVAGDSKND-P-RM---E-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 709)

AAGFT
AQVIIQNHP---GQISAGYAPLLD--------------------CHTARITCKF-AE---
KIVRRSDK-KLEDGP-FLKS--VDATIVDMVPGRPMCVE-----SFSDYPPLRH-FAVCD
MRQI-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KFAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 404)

TYINIV-IIGCV-
DLGKST-T--TGHLIYKCD-GVDKR--TIEKIEKVA-AEMGKGGFKYAW---VL-----D
KL-KAKPECGI--TI-DISLWT-----SETS--KYCVT--ITDAP-----GHR-VIRNMI
T----G-TSQAD-CVLI--VAA-GAGEFEAGI---------SKSGQA-------------
-----------------CEHALL--YTQGVKQPIVGVN--------KMDSTEPPYN--QK
R----YEEIVKE-VSTCIKKI-GYNP--DTVAFVPISGWNGGNMLE-PS-----ANI-PR
-FK---------DGIASGAMLL-----------EALDC---LLPP-PPTDKPLHLPLQ-D
IYR----VGGI-SAVPVGQVETGVLKLG--M-VVTFAPVSV-RTEVKFVEMYPEAL----
----GE--CLPMDNVAFN-VK-----DVSVEDVHHCSVA---------------------
------------GQI

PF03143 // ENSGT00910000144046_0_Domain_1 (556, 658)

SAGYAPVLD--------------------WHAVH-ACKF-AGPKE
KIDH-SGK-KLEDGPKFPKY--GDAAIVDMVPGKPMCVE-----SFSDDLRLGH-FAVH-
--------------------------------------------VIMAVDKKPTGAGRVT
KSAQKAQKAE--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCS-GIDKR--TIGKFENEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CPVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-HKDSNASGTM

PF03144 // ENSGT00910000144046_0_Domain_0 (381, 517)

LL--------------------------------------
--------------------ETGVLKPG--M-VVTFAPVNV-TTEVKSVKMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRG

ENSGT00910000144046_0_Linker_0_1 (517, 535)

NFAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQEIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VG---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTLINIV-IIGHL-
DPGKST-I--TGHLIYKCS-GMDKR--TFERFEKEA-AKMGKGFFKYDW---VV-----D
KL-KAEHERGI--TI-DISLWK-----FKTS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLTVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GLNP--DTVAFVPISGWNGDSMLE-PS-----ANM-PW
-FKGW-KVT-HKDGNASGTCL---------------------------------------
-------------------

PF03144 // ENSGT00910000144046_0_Domain_0 (440, 518)

-ETGVLKPG--M-VVTFAPVNV-ITEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRGN

ENSGT00910000144046_0_Linker_0_1 (518, 533)

IAGDSKNN-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 708)

-E-AADFT
APVIILNHP---GQIRAGYAPVLD--------------------CHTAHIACKF-AELNE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDM----PMCVE-----SFSDYPPLSR-FAVCD
TRQT-VA---------------------------------V--GVNKAVDKKAAGAGKVT
ESAQKAQKPK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIVHV-
DSGKST-T--TGHLIYKRG-GIDKR--TIENFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAECERAI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNARGTTLL-----------EALDC---ILPPTRPADKPLCLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVSFN-VK-----NVSVKDVHHGNVAGDRKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGIT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRHSGK-KLEDGPKFLKS--GDAVIVDMVPGKPMCVE-----RFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAMDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

----------------------------------------------------I-N

PF00009 // ENSGT00910000144046_0_Domain_0 (56, 398)

IGHV-
NSGKST-N--TGHVIYKCG-GINKR--TTENFEEAA--EMRRGSFKYAW---VL-----D
KL-KAEGEC--VITT-DISLWK-----FETR--KYYVT--ITDAT-----GHRDFIQNKI
T----G-TSQAD-CAVLI-VAA-GIGEFEDGI---------SKNGQT-------------
-----------------HEHALLD-YTLPVKQPLVGVN--------KMDSTEPPYG--QK
R----YDEI----------KI-GYNP--DTVAFVLISGWNGDNMLE-LW-----L---SL
-VQGK--VT-CKDGNANGTTLL-----------EALDC---ILPPTFPRAK-----PL-W
ISK----ICGI-GTVPVGRVEIGVLKPG--M-VVTFAPVNV-I---------TEAL----
----SE--VLPGDNVGFN-VK-----NVSVKDVHCGNVAGENKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 663)

-AAGFT
GQLIILIRCSGDSQISAGYPPVLD--------------------CHTAHIACKF-AELKE
KIDHRSGK-KLEDGCKSLKS--GDAPMV-V-------E------SFSDYPPLGC-FTVCD
TRQL-LWVSSKQWTRKLLEDWEFSSVVLLPASQVQGPEFNL--QCQKINKKKTAGTGRVI
KSAQTAK-----------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 661)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPP--L-GR--F
A-C--C----------------------------------------SLVECKVQI-----
----EG---LT-------------------------------------------------
----------------------------------------

------------------------------------------MGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 404)

TYINIV-VIGHI-
DSGKST-T--TGHLIYKCS-GIDKR--TIENFEKEA-AETGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLQK-----FETS--KYYVT--IIDAP-----GHKDLIKNMI
T----G-TSQAD-CAVLI-VAA-GIGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGGNMLE-PS-----ANM-PW
-FKGW-KVT-CKDGNASEATLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPS--M-VVTFAPVNI-TTEVKSVKMHHEAL----
----SE--ALPGDNVGFN-VK-----TVSVKDVRHGNVAGDRKND-P-LM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 637)

-AAGFT
AQVIILNHP---GQISSSYVPVLD--------------------CHTAHIACKF-AELKE
KTDRCSGK-KLEDGPKFLTS--GDAAIVDMVPGKPVCKL-----SCIAGGDIKW-CSCCG
-KRF-GG---------------------------------S-------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKENIQINIV-VIGHVV
DSGKST-T--TGHLIYKCG-GIDKR--TMEKFEKEA-ADMEKGSFKYAI----L-----D
QL-KAAHECGI--TV-DISLWK-----FETS--KYYA-------P-----GHRDF-KNMI
M----D-TSQPD-CTVLI-VAT-GVGEFEAGI---------SKNGQA-------------
-----------------HEHALLA-YTLV-----------------KTDSMEPHYN--QK
S----YREVIKA-DNTYIKKI-GYNP--NRVAFVPISGWNGDNMLE-PS-----AKV-PW
-FKGW-KVIPKMGIPVEPQCLS-------------FGL---HSATTHSTDKRLHLPLQ-D
VFK----FGGV-D

PF03144 // ENSGT00910000144046_0_Domain_0 (434, 518)

TVPVGRMAAGVLKPG--I--VTFAPVNV-TTEVKSVEMHHETL----
----SE--ALPGDIVGFH-VK-----NVPVKEVHCGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-LR---D

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYVPVLD--------------------YHTAHIACRF-AELKE
-------K-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SCSDYPLWGH-FAVCE
TRQT-VA---------------------------------V--GVIKAVDRKAAG-GNTA
KTAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 398)

KTHINII-LIRPG-
DSGKST-T--TGHLIYKCG-GIDKR--TIETFEKET-SEMGKGSFKNAW---VL-----D
KL--------------------------KTS--KYYVT--ITDAP-----GHRDFIKNMI
T----G-TYKAD-CTVLI-VAA-GVGEF--------------------------------
------------------EHVLPA-YSLGVKQITVGVN--------KMNSTE--------
-----YEEIVKE-VSTYMKKI-GYNP--DTVAFVPISDWNGDYMLE-LG-----ANM-LW
-FKGW-KVT-QKDGKASGTTLF-----------EALDC---ILPPTHPTDKPLRLPLQ-D
---------------------TGVLKPG--M-VVTFTPVNV-TTEVKSAEMNHENLS---
-------------------------------DVHCGSVASDSKND-P-LL---E-A----
-

PF03143 // ENSGT00910000144046_0_Domain_1 (542, 708)

-VIILNHP---SQISAGYTPVPD--------------------CHTAHIACKF-AELKE
KIDCWSGK-KLENGPKFLKS--GDNAIVDMVPGKPMCTE-----SFSDYPSLGH-FAVCN
IKQT-VA---------------------------------V--GVIKAMDKKAARAGKIT
KSDQKDQKPK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHV-
DLGKST-A--TGHLIYKCG-GIDKR--TIKKFEKEA-AEMGKGSFKYAW---VS-----D
KL-KAEHEHGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGVN--------KMDSTELPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVSISGWNGDIMLE-PI-----------
--------T-RKDGNASGTTLL-----------EALDC---ILPPICPTDKPLHLPLQ-D
VYK----IGGI-GTVP-----TGVLKPS--M-VVTFAPVNV-TTEVKSVEIHHEAL----
----RE--ALPGDNVGFN-VK-----HVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------YHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKATGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 345)

KSHINIV-VIGHV-
DSGKST-I--TGHLIHKCG-GIDKR--TIKKFVKEA-AEMGKGSFKYAW---VL-----N
KL-KAECERGI--TI-EFSLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAAI---------SKNGQT-------------
-----------------RKHALLA-YTLGVKQLIVGVN--------KKNSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--ETVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGHASGTTLP-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--I-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRCNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYALVLD--------------------CHTAHIACKF-AELKE
KIDHCSGK-KLEDGPKFLKS--GDAATVDTVPGKTMY-----------YPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAV-----------
-DKKAA----GAGKVTKSAQKAQ---------KAK-------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHVNII-VIGHV-
DLGKST-T--IGHLIYNCV-GIDKR--TIEKFEKEA-H----------------------
-------ERRI--TV-DISLWK-----FETS--KYYMT--IIDVA-----GHRDFIKNMI
T----G-TSQAD-CTVLI-VAA-SVGEFEAVI---------SRNGQT-------------
-----------------REHALLA-YTLGVKQLIVGIN--------KMDSTEPPYS--QK
R----YEEIIK-------EKT-GYNP--DTEAFVPISGWNGDNMLE-P------------
-----------SDGNTSGTMLL-----------EALDY---ILPQTHPTNKPLCLPLQ-D
---------------------TGVLKSG--M-VVIFAPVNI-KTEVKSVEMHQEAL----
----SE--TLSGDNVGFN-VK-----NVSVKDVHHGNDAGDSKDD-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHTASKF-AELKE
KMDRHVGK-KLEDGPNFLNS--GDAANVDMVPGKPVCVE-----CFSDYPPLGR-VAVHD
MRQT-VA---------------------------------V--DVIKAVNKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGTKKVHIYIV-IIGHV-
DLGNST-T--TGHLIYKYG-GIDKR--IIEKFEKEA-AELGKS-SKYAW---VL-----D
KL-KAEHKRGI--TI-DISLWK-----FETS--KYYVI--IIDAP-----EHRDFIKNMI
I---------GS-CAVLI-VAA-GVGKFEAGI---------SKNGQT-------------
-----------------HEHALLA-YPLGVKQLIVGVN--------KMNSTEPPYS--QK
R----YEEIVKK-K-------IGYKP--DTIAFMPVSGCKGDNMLE-SS-----ANM-PW
-FKGW-KVT-HEDGTASGTTLL-----------QALDC---ILLPAPPTDKPLSPPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEV--VKMHHEAL----
----SE--ARPGDNAGFN-VK-----DVSVKDVHRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGCT
AQVIIRNHP---GQISTGCTPVLA--------------------CHMAHTVGKF-AKLKE
KIDHLFSK-KLEDGPKFLKS--GNTAIVDMVPGKPMCVE-----SFSD-----L-FAVRD
MRQT-VA---------------------------------V--GVIKAVNKRAAGAGKVT
KSSLKAQKAKR-------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIE-VIGHR-
DSGKS--T--TGHLIYKCS-GIDKR--TIENFEKEA-AEMGKGSCKDAW---VL-----D
EL-KAERERGI--SI-DISLWK-----FKTS--KYYVT--ITDAP-----A---------
-----------D-CAVLI-I-A-A-GDFEADI---------SKNGQN-------------
-----------------RECALLA-YTLGVKQLIVA-N--------KMDSTEPPYS--QK
R----YEEIV--------KKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANK-PW
-FKGW-EVT-QKYGNDSGTTML-----------EALDC---ILPPSHPTDKPLCLPLQ-D
VDK----TGSI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVG-VETGVLKPS--M-VVTFAPVNI-TTE------HHEAL----
----SE--TLPGDNVGFN-VK-----NMSVKDVRHGSVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKSD-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 589)

LA---E-AAGFT
AQVIILSHP---GQVSAGDAPVLD--------------------CHTTH-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---M

PF00009 // ENSGT00910000144046_0_Domain_0 (125, 404)

SERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQXIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------VGKEKTHINIV-VIRHV-
DSGNST-T--TGHLIYKCG-GINQL--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAE-----------------------RD--KYYVT--IID-----------------
----------AD-CAVLI-VAA-GAGEFEAGI---------SKNRQT-------------
-----------------HEHVLLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VITYIKKI-GYNP--DTVAFV--------------------------
---------------ASGTTLL-----------EALDC---ILSPTRPTDKPLRLPLQ-G
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 524)

GTVPVGRVEAGVLKSG--M-VVTFAPVNV-TTEVKSVELNREAL----
----SE--ALPGDNVGFN-VK-----NV------------DSK

ENSGT00910000144046_0_Linker_0_1 (524, 535)

ND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 662)

-AAGFT
AQVIILNHP---GQISAGYASVLD--------------------CHTAHIASKF-AELKE
KIDCLSGK-KLEDGPKFLKS--GDAAIVGMVPGKPMCVE-----SISDYPPLGR-FAVHD
MSCC-I------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-IIGHV-
DSGKST-T--TGHLTYKCG-EIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEREHGI--TI-D-SLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAG----------SKNGQT-------------
-----------------RERALLA-YTLQKR-----------------------------
-----YEEIVKE-VSTYIKKI-GYNS--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 516)

GTGPVGRVETGVLKPG--M-GVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRR

ENSGT00910000144046_0_Linker_0_1 (516, 529)

GNGAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQAIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRHSRK-KLEDGPKFLKS--GDAVIVDMVPGKPMCVE-----SFSDYPPLGC-FVVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LDSTEPPYS--QK
R----YEKIVKE-VSTCSKQI-GYNP--DTVAFVPISGWKGDNMLE-TS-----ANT-PW
-FNRR-EVT-----------RK-----------DALDC---ILPPTRPTDKPLRLPFQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GAVPVGRAETGVLKPG--M-VGTFAPVNV-TTKVKSVEMYQEAL----
----SE--ALPGGNMGFN-VK-----NLSVKDVHRGN

ENSGT00910000144046_0_Linker_0_1 (518, 537)

VAGDT--------------

PF03143 // ENSGT00910000144046_0_Domain_1 (537, 720)

AGFT
AQAIILNHP---GQISTGYVPVLD--------------------RHTAHIACKF-TERNE
KIDHHSGK-KLEDGPKFLKS--GDATIVDMVPGKPMCVG-----NVSDSPPLDR-FAVHD
VRQI-V---------------------------------------------AMAGAGKVT
KPAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AELGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DSSLWK-----FETS--RYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIIGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-A------TVAFVPISGWNGDNMLE-PS-----------
-------VT-RKDGNTSGTMLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPT-----GVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRHGSVAGDSIND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---CQISAGYAPVLD--------------------CHTAHIACKF-AEPKE
KIDCRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEQPSS--QK
I----CEEILKE-VSTYIKKI-GYNP--DMVAFVPISGWNGDNMLE-LS-----ADM-PQ
-FKGW-KVA-RKDGNARGTTLL-----------EALDC---ILPPAHPTDKPLRPPLQ-D
VYK----IDGI-GT-------TGVLKPD--M-VVTFAPVSV-TTEVQSVEMHHEATTIDN
LLPLFE--ALPGDNVGLN-VK-----TL------------SEQNA-P-AM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 654)

-E-AAGFP
AQVITLNHL---GQISAGCAPVVH--------------------CHTAHIACKC-AELKE
KTDCRSGK-KMEDRPKFLKF--GDAAIVDMVPGKPMCG------SFSNYPPLGC-SAM--
-----VA---------------------------------V--GVIKAADQKASGATKEV
RKSHEARLQAKKAEIIKTLSKEE--E------TKK-------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 529)

AGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTNIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFI
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 301)

KTHINIV-ITGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TNKKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEREHVI--TI-DISLWK-----FETS--KYYMT--VIDAP-----GHRDFIKNTI
T----G-TSQAD-CAVLI-VAA-SIGEFEADI---------SKNGQT-------------
-----------------CEHALLA-YTLCVKQLFVGVS--------KMDYTEPPIS--QK
S-----------------------------------------------------QVI-TS
-IKGW-KVT-HKDGNASGTTLL-----------GALDC---ILPPTHPTDKPLRLHLQ-D
SYK----IGGI-GTVPT-----DVLKPS--M-VVTFAPVSV-TTEVKSVEMHHEAL----
----SE--APPGDNVGFD-VK-----NVSVKDVRRGTVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHL---GQIS------------------------------TAHIACKF-AELKE
KIDHSCGK-KPEDGPKFLKS--GDTAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVCD
MRQT-VA---------------------------------V--DVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV--IRHM-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-DEMGKGSFKYTW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETR--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNRQT-------------
-----------------HEHALLA-YMLGVKQLIVGVN--------KMDSTEPSYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNLLE-PS-----ANM-PW
-FKGW-KVT-HKDGNASGTTLL-----------EALDC---ILPPTCPTDKPLGLPLQ-D
VYK----IGGI-STVP-----

PF03144 // ENSGT00910000144046_0_Domain_0 (442, 516)

TGVLKPG--M-VVNFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NMSVKDVHH

ENSGT00910000144046_0_Linker_0_1 (516, 535)

SNVASGSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 657)

-AAGFT
AQVIILNHP---GQITAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRPSGK-KLEDGPKFLKS--GDAAIIDMVPGKPMCVE-----SFSDYPPLGC-FTRMC
F----VD---------------------------------H--LFS-------------F
CV----------------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVLANPCVSR-----AFSEYLLSGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MKKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGPV-
DSGKST-T--TGHLIYKYG-GIDKR--TIEKFEKVA-AELEKGSFRYAW---IL-----D
KL-KAERERGV--TI-DISLWK-----FETS--KYYMT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGS---------STNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDFTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLQ-PS-----ANM-PW
-FKGW-KVT-PKDGKASGTTLL-----------EALDF---ILPPTRPTDKPLRLPLQ-D
VYK----IGDI-GTVPVGRVETGGLKAG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NASVKDVRCGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
ARVIILNHP---GQISAGYAPELD--------------------CHTAHIACKF-AELKE
KIDRHSGK-KLEDGPKFLKS--GDAANVDMVPDKPMCVE-----SFSDYPCLGR-FAVRD
MRQT-VA---------------------------------V--GIIRAVDKKAVGAECH-
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDS---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGILKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--AFPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------TGKEGA

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 345)

HSNTV-LIRRV-
GSGWST-T--AG-LIHKRG-GVDRR--TTENFEEAAAA-------MQAW---FV-----D
KM-KADG--EPCGTP-DISPWQ-----LEAS--KYYVA--ILDAP-----GHRDFIMNVI
T----A-PSQAD-RALLV-VAA-SAGEFEAVF----------KIGQP-------------
-----------------WEHAILA-YTLAVKQFRVDTN--------NMDSTTTDSQ---K
K----RRKLLR---KSYIKKI-GYTP--NTVAFGPISGWNGDNTLSQVL-----T----C
--LGS-KAR-RSSIGEPCRWSR-----------AASSS---ALPPTCPTDKPLRLPLQ-D
TYE----IGGF-GTVPV----GGVLELG--T-VDPFAPVNV-TAEVKWVEMHLEAL----
----SE--DLPRDNVGFS-VK-----NVSVKDVHHDNMAGDSKNEWP-PM---K

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 708)

-AAGFA
AQLIVLNCP---GQISAGYPCLLD--------------------CHPARIACKF-AELKK
-IDPCS-K-NLEDSPKVLKS--GDATTTDTVLG-----------KFYDHLPWGC-FTVCD
KRQI-VA---------------------------------V--GVIEAADKKVTGADEVT
STARKLEGRNVK------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-I--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKHAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------

PF03144 // ENSGT00910000144046_0_Domain_0 (287, 519)

KMDST---------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------EMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRPGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------VGK-EKTA-TS-ITGHV-
DSGKST-T--TAGM--------DEG--TEKC--TKEAAEKGGGFFKSSC---VL-----D
KL-KAEREHG--VTT-DIALWK-----FEP---SRWVT--IIDAR-----GHRHVE-NMT
A----E-TSQAA-CAVLV-AAA-GVGECEAGI---------SKIGQT-------------
-----------------REHALLA-NTLGVKQLLVGVN--------NGDSTEPAYS--QK
K----YEEIVQE-GSTDIEKS-GYKP--RTVAFVPISGWNGDNMLE-PS-----ANK-PW
-F-GW-KVT-HKAGNASGTMLL-----------DALDC---ILPPTHRTDKLPLKDV---
YKL-----VDT-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 510)

GTVAVGREETDILKPG--V-VVTFASVNA-ATEVKSVEMHHAAL----
----SE--ALPGNSVAFN-VQ-----NVS

ENSGT00910000144046_0_Linker_0_1 (510, 529)

VP---HGKVPGDK-RNDL-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 620)

PR---E-EGSFT
AQVIILNHP---GQISAGA---------------------------PM------------
-LDCHPAH-IAYKFAVLLGRR----M-------------------CESCPLWGC-SAVRY
MRRA-VA---------------------------------V--G-IKALDKKAARAGKIT
QSAQQKL-----------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHVNII-VIGQV-
DSYKST-T--TSHLIYKS------------------------GSFKYAW---VL-----D
KL-KAKCECGI--TI-DISLWN-----------KYYVT--IIDVP-----GHRDFIKNMI
A----G-TSQAD-CAALI-VAA-GVSEFKAGT---------SKNGQT-------------
-----------------HEHALLA-STLGVKQLIVGVN--------KMDSTEPPYK----
-------ENVKE-VSAYTKKI-GYNP--DTVAFVPISGWNADNTLE-PN-----ANM-PW
-FKGW-KVT-RKDGSSSGTTLL-----------EALDC---ILPPPPPTDKPLRLPLW-D
VYK----IGGI-GTVPVNQ

PF03144 // ENSGT00910000144046_0_Domain_0 (440, 517)

VDTGVLKPG--M-MVTFAPVNV-TTEIKSVEMHHEAL----
----SE--ALPGDNMGFN-VK-----NVSVKDVRRG

ENSGT00910000144046_0_Linker_0_1 (517, 543)

NITGDSKND-P-PM---G-AG---
EM

PF03143 // ENSGT00910000144046_0_Domain_1 (543, 709)

VIILNHP---GPISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLES--GDAASFDRVPGKPMCVE-----SFSDCPPLGR-FAVHD
MRQT-VA---------------------------------V--GIIKAVDKKAAGAGEVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHV-
DYGKST-T--TGHLIYKCG-GIDQR--TIKKFEKES-AEMGKGSFKYAW---VL-----N
KL-KAEHERGI--TI-DISLWK-----FETS--KYCIT---IDAP-----GHRDFIKNMI
SA-GLG-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------CEHALLQ--------LIVGIN--------KMDSTEPPYS--QK
S----YKEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PSHLWPYTNM-PS
-FKGW-KVT-CKDGNASRTTLL-----------EALDC---ILPPTHPTDKPLHLPLQ-D
VYK----IGGI-GTVPVGQVETGVLKPG--M-VVTFAPISV-TTEVKSVEMHHEAL----
----SE--APPGDNMGFN-VK-----NVSVKDVHRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHI-------LKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPLLGH-FAVRD
MRQT-VA---------------------------------V--CVIKAVDKKAAKAGKVT
KPAQKVQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 308)

KTHINNI-IIGHM-
DSGKST-T--TAHLIYKCG-GINKR--TIEKFKKEA-AEVGKGSFKYTW---VL-----G
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CVVLI-IAT-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLAY-----------------------------------
-----AKEGRKE-VSTYIKKI-GYNP--DTVGFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVP-CKDDNASGTTLL-----------EALGC---ILPPTHPTDKPLRL-----
------------GTVPVGRVETGVLRPG--M-VVTFTPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVCHGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHL---GQISAGYAPVLD--------------------FHTVHIACKF-AELKE
KIDRRSGK-KLEAGPKFLKS--GDAAIVDMVAGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGNE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINSI-VIGHV-
DSSKST-T--TGHLIYKCG-GINKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEC-EGI--TI-DISLWK-----FKTS--KYYVT--IIDAP-----GHRGFIKNMV
T----D-TSQAD-CAVLI-VAA-GVGEFEAGI---------FKNGQT-------------
-----------------REHALLA-YTLGIKQLIVGVN--------KMDSTEPPYS----
------EEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNILE-PS-----ANV-PW
-FKGW-KVT-CKAGNASGTTLL-----------EALDC---SLPPTRPTDKPLRLPLQ-D
VYK----IG----TVPVGRVETGVLKPG--M-VVTFATVNV-TPEVKSVEMHPEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRHGNVSGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVSILNRP---GQISAGYTPVLD--------------------CHS--MACKL-AELKE
KIDRRSGK-KLEDGPKFLKS--RDAAIADMVPGKPMCVE-----SFSDYPPLGR-FAVRD
VRQT-VA---------------------------------V--GVIKAVDRKAAGAGKVT
KPAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKL

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 402)

HTNTV-IIGHA-
DSGDLP-R---------------------------G-ILEGKGSFKYAW---VL-----D
KL-KAEHECGI--TF-DVSLWK-----FKNS--KFYVT--IVDAP-----GHRDFIKDMI
T----G-TYQAD-CAVLI-VAA-GVGEFKAGI---------SKNRQI-------------
-----------------CEHAFLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GCNP--NTVVFVPIS-----------------------
-------VT-CKDDKASRTTLL-----------EALNC---ILPPIRGVSVIAQ------
-----------------GK-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHLNIV-VIGHV-
DSGKST-T--TGHLIYKCG-GINKR--TIEKFEKK-----------AAW---VL-----D
KL-KAEHERSI--SI-DTSLWK-----FETS--KYYVT--MINAS-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFETGI---------SKNGQT-------------
-----------------REYALLA-YILSVKQLIVGVN--------KMHSTEPPYS--QK
R----YNEIVKE-VCTYIKKI-GYNP--DTVAFVPISGLNGDNMLE-PS-----ANM-PW
-FKGW-KVT-CKGGSASGTTLL-----------KALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGT-GTDPMGQVETGVLKPG--M-VVTFVPVK-----LKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRAMLLVTARMI-P-PW---R-EL---
--------A---

PF03143 // ENSGT00910000144046_0_Domain_1 (553, 709)

SLLSAGYAPVLD--------------------CHTAHIACKF-AELKE
KTDRHSSK-KLEDGPKFLKS--DDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FAVRN
MRQT-IA---------------------------------V--GIIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGEEKTHINIV-VIGYV-
DSGKST-T--TGHLSYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERECGI--TT-DISLWK-----FETS--KYYVT--IIDAP-----RHRDFIKNMI
T----G-TSQVA-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGFN--------KIDSTEPPYS--RK
R----YEEIVKE-VSTYIKKI-GYNP--NTVAFVPISGWNGDKMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTPL-----------EALDC---ILPPTRPTDKPLL------
--------------

PF03144 // ENSGT00910000144046_0_Domain_0 (435, 518)

-E-----TGVLKPG--M-AVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPRDNVGFN-VK-----NVSVKDVHRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDGKNN-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHS---GQINAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRCSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVCD
MRQI-IA---------------------------------M--GVIKAVDKK-AGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 712)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVS-----SRFAVRD--M-RQ--T
V-A--V----------------------------------------GVIKAVTKS-----
----AQ---NSSR-----------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 403)

KTHINII-VTGHE-
DSGKST-T--TGHLIYKCC-GINKR--TIKKFEKEA-AEMGKDSFKYACVLCVL-----D
KL-KAECEHDI--II-DVSLWK-----FETS--KY-VT--IIDAP-----GHKDFIKNMI
I----G-TSQAD-CSVI--VTS-GVGKFEVGI---------SKNGQT-------------
-----------------HEHALSH---TNVKQLIVDVN--------KMDSTELPYS--QK
R----REEIVKE-VSTYIKKI-GYNP--GTVAFMPISDWNGDNTLE-PS-----ANI-PW
-FKGW-KVI-RKNGNASGTMLL-----------EALDC---ILPPTCPTGKPLRLPLQ-V
VYK----IDGI-GTVPVGRVETDILKPG--M-VVTFDPVNV-TTEAQSVEMHHEAL----
----SK--ALPGNNVGFN-VK-----NTSVKDVCCGNVAGDSKND-P-SM---D--A

PF03143 // ENSGT00910000144046_0_Domain_1 (538, 709)

GFT
AQVIILNKP---DQISAGYAPVL---------------------CHAAHIACKF-TELKE
KIDRHSGKKKLEDGPKFLKS--GDAAIINMVPGKPMCVE-----SLSDYSTLGY-FAIRY
IRQT-VA---------------------------------V--GVIKAVDKKAAGISKVT
QSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKDKTHINIV-IIGHV-
DLGKST-T--IGHLVYKCG-GLNKR--TIEKFEKEA-AEMGKGSLKYAW---VL-----D
KL-KAECERGI--TI-DISLWE-----FETS--KYYVT--IIDAP-----RHRDFI-NMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGV---------SKNGQT-------------
-----------------CEHAPLA-YTV------------------------------QK
R----YEEIIKG-VSTYSKKL-GYNP--DTVAFVPISGWIGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------KALDC---ILPPTHPTDKPLCLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVSRVETDVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDSVGFN-VR-----NVSVKDVCRGS

ENSGT00910000144046_0_Linker_0_1 (518, 533)

VTG----D-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-K-AVSFM
VHVISLNHP---GQISAGYALVLN--------------------CHTAHIACKF-AELKE
KIDRCSGK-KLEDGPKFSKS--RDAAIVDMVPGKPMCVE-----SFSDYSPLGR-FAVRD
MRQT-VD---------------------------------V--GVIKAVDKKAAGAGKVT
SLPRKLRRLN--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 380)

KTHINIA-VIGHI-
DSGKNA-V--ESTNEPSKSLKRRLP--E-----------MGKGSFKYAW---VL-----D
KL-KAERERGM--TI-DISLWK-----FEIS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVCEFEN--------------EQN-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTKLPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTIAFVPISGWNGDNILE-PS-----SNM-PW
-FKGW-KAT-HKDGSASGTTLL-----------------------------------E-D
VYK----IGGI-GTVPTG-----VLKPG--M-VLTFALVNV-STEVKSVEMYHEAL----
----SE--ALPGDNMGFN-IK------------NTSDVAGDSKND-P-PM---K

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQGIILNHP---GQISDGYAPVLD--------------------CHT------F-AELKE
KIDRRSGK-KLEDGPKFLKS--G----------DPMCVE-----SFSDYPPLGH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKSQKTK--------------------------------------------------
----------------------------------------

------------------------------------------MGKERTHINIV-VIGHV-
DSGKST-T--SGHLIYKCG-GIDKR--TIEKLEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-ISQAD-CAVLI-VAA-GVSEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPCS--QK
R----YEDIVKE-ISAYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-K---------------------------ALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVLVGRVETGILKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
VQVIILNHP---GQISSGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIADMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-LA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SQNGQT-------------
-----------------CEHALLA-YTQGMNVN-------------QMDSTETSYN--QK
R----YGKLIKKEKKRKEKKI-VYNP--DTVAFVPLSSWNGD-MLE-PS-----P-S-IW
-FEGW-KLT-HKHDKASATTLL-----------EVLDC---IPLPSGPTDKPLLLPLI--
--------GGI-DTVPMSRE

PF03144 // ENSGT00910000144046_0_Domain_0 (441, 513)

ETGVLKPS--M-V-VFSPVSV-TTEVKSIETPHDTL----
----SE--PLPGDSVGFS-VK-----NVSVKD

ENSGT00910000144046_0_Linker_0_1 (513, 537)

VHCDSVAGDSKND-L-PV---D-A

PF03143 // ENSGT00910000144046_0_Domain_1 (537, 709)

GDFM
AQVIIMNHP---G-------------------------------FHIAHIACKC-AELKE
KIDHCSGN-KWEDGPKFLKS--RDAVLIDRGPGKPMHVE-----SFSDYPAPGH-FAVSD
MSQM-VA---------------------------------V--GIVKAVDEKAAGAGKVT
KPAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEV-AEVGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAT-GVGEFEAG----------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEVIKE-VSTCIKKI-GYNP--NT-AFVPISSWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------GALDR---ILPPTPPTDKPLRLPLQ-D
VYK----IGGI-GTVPVS----D

PF03144 // ENSGT00910000144046_0_Domain_0 (444, 515)

VLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALSGNDVGFN-VK-----NVSVKDVR

ENSGT00910000144046_0_Linker_0_1 (515, 529)

RDNMAGDSRND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFM
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRHSGK-KLEDGPKFLKS--GAAAIVDMVPGKPMCVE-----SFSDYPPLGC-FDVHD
MRQR-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHINIV-IIGHV-
DSGKST-T--TGHLIYKWG-GIDRR--TIEKFEKEA-AEMGKDSFKYAW---VL-----D
KL-KAEREQGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----RHRDFIRNMI
I----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGHT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--PK
R----FEEIVKE-VSTYIKKI-GHNP--DTVAFVPISGWSGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTHPTDKPLHLPLQ-D
VYK----IGGI-STVPIRRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-PP

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKL-AELKE
KIDRCSDK-KLEDGQKFLKS--GDAAIVDMAPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDK---------
---KA----AGAGKVTKSAHKAK-------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KIHINII-VIGHV-
DSGKST-T--TGHLMYKCG-GINKR--TIKKYEKEA-AQMGKGSFKYAW---VL-----D
KL-KAECESGI--TI-DISLWK-----FKTS--KYY-T--IIDAP-----GHRDL-KNMI
T----G-TSQAA-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQVIAGVN--------KMDSTEPPYS--QK
R----YKGIVKE-VSTYIKKIGGYNP--DTVAFVPISGWNGDNMLE-PS-----ANV-PW
-FKGW-KVT-RTDGNASGTTLL-----------EAWDC---ILPPTRPTDKPLRLPLQ-D
VFK----IGGI-GTVPVGQGETGVLKPG--I-VVTFAPVNV-TMEVKPVEMHHEAV----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFA
-QVLILNHP---GQI------VLD--------------------GHTAHIACRF-AEPKE
KIGRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPRCVE-----SSSDYPPLGR-FAVRD
MRQT-VA------------------------------------GVIKAVDKKAAGAGKVT
KSAQKLRRKNK-------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------LI
T----G-TRQAD-AAVLV-VTA-GVGEFEAVI---------SKTVQT-------------
-----------------CEHALLT-SIL----------------GI--PPTPPTTTTSQK
R----CEEIVTE-TSTHMKKT-SYDP--DTVALGPFADWNIDNILE-LS-----SNP-TW
-FKRW-KVI-QKEGNANGTALP-----------EALDC---ILPPCHPTVPT--------
--------------PPKLVVLTGISTRH--G-GPLLPRVSV-TTKVKCVEMYHEAL----
----SE--AMPGDHIGFI-VK-----NISVTDVCHG---GNSKNE-L-TM---K-SAGF

PF03143 // ENSGT00910000144046_0_Domain_1 (540, 708)

V
QVIILNHV----GQIRTGCAPILG--------------------CHTAYIACKF-AE---
-RN-CSGK-KLENSPKFLKS--GDAAIVDMFPGKPVCVE-----SFSDYPPLSY-FAICD
MRQT-TA---------------------------------V--GVIKAADKKAAGAGKVT
KSAQKAK-----------------------------------------------------
----------------------------------------

------------------------------------------MGKEKAHINLV-VTGHI-
DSAKST-T--TGHLIYKCN-GIDKI--TLEKFEKEA-AEMGKCSFK-AW---VL-----D
KL-KAECEQGI--TI-DISLWK-----FENP--KYYVT--IIDAP-----GHRNFIKNKI
T----G-ISQAD-CVVLI-VA--AVGECEAGI---------FKNWQT-------------
-----------------CEHALLA-HTMGGKQLIVGVN--------KMDSTEPTYS--QK
R----YEKIVKE-VSTYIKKI-GYSP--DTVAFVPISG----------------------
-FKGW-KFT-QKDCNASETTL------------LALDC---ILPPTYPNEKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETSVLKPG--M-VVTFAPVNV-TTEVKSVH-HHEAL----
----SE--ALPGDNVGFN-IK-----NVSVKDVHYGNES

ENSGT00910000144046_0_Linker_0_1 (520, 535)

NDSKND-P-P-----

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 636)

-AAGFT
AQVIMLNHP---GQIGAGYAPVLD--------------------CYTARISCKF-AELKE
KFDHCSGK-KLEDGPKFLKS--SDAAIIDVVPGKPM------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

-------------------------------MGKKKTHIKIVVIGH

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 407)

GDHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYMT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CSVLI-VAA-GVGEFEAGI---------SENGQT-------------
-----------------GEH---A-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISSWNGDNVLE-SS-----ANM-PW
-FKGW-KVT-HKDGNGSGTTLL-----------EALDC---VLPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAS----
----SE--ALPDSMSRLSHSS-----RVSVKDVRRGGVADEGKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
GQVIILNHP---GQISAGYAPVLD--------------------CHIAHVACKF-AELKE
KIDRRSGK-KPEDGPKFLKS--GDVAIVDMVPGKPMCVE-----SFSDSPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKVAGAGKVI
KSSQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGMEKTHMNII-VIGPI-
DLGKST-T--TGYLIYKCG-GI---------YEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEHEHGI--TI-DISLWK-----FEIS--KYYMT--IIDAP-----GHT-----MI
I----G-TSEAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIIKE-VSTYIKKI-GYNP--NTVAFVTISGWNGDNMLK-PT-----ANM-PW
-VKGW-KVT-CKDGNASGTTLH-----------EALDC---SLSPTHPTDKPLHLPLQ-E
VYK----VGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRMETGVLKPG--M-VVTCAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGLN-VK-----DVSVRDVRHGN

ENSGT00910000144046_0_Linker_0_1 (518, 529)

VAGDSKNE-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFI
AQAIILNHP---GQISAGYASVLD--------------------CHTVHIACKLAE--LK
KIDRRSGR-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGC-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

---------------------------------------MGK---E

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHI-
DSGTST-T--TGHLIYKYG-GIDKSIPTIEKFEKEA-AEMGKGSFQYAW---VL-----D
EL-KAEREHGI--TI-DISLWK-----FETS--KYYVI--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------CGHALLA-YTPGVKQLIVGVN--------KMDSTEQPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--YT-AFVVIFDWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASRTTLL-----------EALDC---ILPPTRPTDKPLRLP-Q-D
VYK----IDGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAG----D-P

PF03143 // ENSGT00910000144046_0_Domain_1 (528, 709)

-PK---E-AAGFT
AQVIILSHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDHPPLGR-LAVRD
MRQT-VA---------------------------------V--GVIKAVDK-AAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PN-----ANM-PW
-FKGW-KVT-RKDGNANGTTLL-----------EALDC---ILPPARPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKSG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----RE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 539)

VAGDSKND-P-PM---E-GAG

PF03143 // ENSGT00910000144046_0_Domain_1 (539, 709)

VT
AQVIILNHP---GQISAGY-----------------------------------FAELKE
KTDRRSGK-KLEDGPKFLKS--GDAAIIDTVPGKPMRVG-----SFSDYPLLGH-SAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KPAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 345)

KTHINIV-IIGHV-
DSGKST-T--TGHLIYKGG-GIDKR--IIEKFEKEA-AEMER------L---LQ-----D
KL-KAECEHGI--TI-DISLWK-----FENS--RYYVT--IIDAP-----GHRDYTKNMI
P----G-TSQVD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------CEH-LLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--NTVAFVPISGWNGDNMLE-PS-----ANM-PW
------KVA-RKDGNASGTTLL-----------GALDC---I-PPTCPTDKLLRLPLQ-D
VYK----TGGI-DTVP----ETGVLKFG--M-VVTLAPVNV-TTKVKSVEMHHEAL----
----TE--ALPGDNVGFN-VK-----NVSVKDVHR-NVAGDSRNE-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-ATGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDHCSGE-KLEDGPKFLKS--GDAAIVDVVPGKPLCVE-----SFSDYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSARKKSTRKIK------------------------------------------------
----------------------------------------

------------------------------------------IGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 404)

TYFNIV-VIGHI-
DSGKST-T--TGYLIYKCGE-INKQ--TIEKFE-EA-SETGKGSFKYVW---VL-----D
KI-KAECECGI--TI-DISLWK-----FETS--KYYVT--IIDTP-----THREFSKNMI
T----N-TSEAD-CVVLI-VAA-GVGEFEAGI---------SKNEQT-------------
-----------------GEHALLA-FTLGVKQLIVGVN--------KMDSTDLWGT--F-
-----SFKPSQE-VSTYIKKI-GYSP--DTVAFVPLSGWNGNNVLE-PS-----ANM-PW
-FKGW-KVT-CKDGSASGTKLL-----------EALDC---ILPPTCPTGKPLGYL----
------------------------------------CSSQC-QTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVQRGNVAGEGKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVQD--------------------CHTAHI----------
-----------SYGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSNYPPLGH-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVA
KSAQKAQKAE--------------------------------------------------
----------------------------------------

---------------------------------KPPLNLN-QNGKRKD

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 397)

SSNTV-VIGHI-
DSDKAT-P--TGHLIYKCG-GIHKR--TIEKFEKEA-SEMGKA-LQVGW---VL-----D
KL-KAEHE------I-DISLWK-----FETS--RYYVI--ITDVP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGELEAGI---------SKNGQT-------------
-----------------CEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEMVKE-VSTYTKKT-DYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-LKGW-KIP-RKDGSASGTTLL-----------EALVC---IRPSTHSTDKPSHLPLQ-D
VYK----ISGI-GTVPVGRVETWVLKPG--M-VVTFAPVNV-TTEVKSIEMHHEAL----
----SE--ALPGDNVGFN-VK-----KVSVKDVRHGNMAGNSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNYP---GQISAGCSPMLD--------------------CHTAHIACKF-AELKE
KIDRHSGK-K-EDGPKFLKS--RDAAIVDMVP-KPMCVE-----SFSDSPPLGH-FAIRD
MKQT-VA---------------------------------V--GVIKVVDKNAAGAGKVI
KSAQKAQKTK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------W---VL----

PF00009 // ENSGT00910000144046_0_Domain_0 (119, 332)

-D
KL-NDELEYCI--TI-DISLWK-----FETS--KYYVT--VIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEF--------------------------------
------------------EHALLA-CILGVKQLIVGVN--------KMDSTEPSYS--QK
R----YEEIFKE-V----------------ITFVPISGGNGDNMME-PS-----ANM-PW
-FKGW-KIT-HEDGNACGATLL-----------EALEC---ILPPTHPTDKPLHLPLQ-D
VYK----IDGI-GTVPTG-----VLKNG--M-AVTFAPVNV-TTEVKSVEMHHEVL----
----SE--ALPGDNVDFD-VK-----NVSVKEVHHGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 708)

-KAGFT
AQVIILNHP---GQISAGCAPVLD--------------------CHMAHIACKF-AELKE
KTGSTSAK-KLEDGPTFLKS--GDAAIVDMVPGKPMCVE-----SFSVYPPLSR-FAVCD
MRQT-VA---------------------------------V--GVIKAMDKKAAGAGKVT
KSTQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINII-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANK-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHTACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDTAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 345)

AHINIV-VIGYI-
DSGKST-T--AGHLIYKCG-GIDKR--TIEKFEKEA-AEIEKGSFKYAW---VL-----D
KL-KAKCERGI--TI-DISLWK-----FETS--KYYVT--IIDVP-----GHRDFIKNLI
M----G-SSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------RDHALLA-YTLGVKQLIVGVN--------KVDFTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPICGWNGDNMLE-PS-----ANM-LW
-F----------------------------------------------------------
----------------KGW--KVTRKPG--M-VVTFAPVNV-TTEVKSVEMRHEAL----
----SE--ALPRDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--DDAPIIVMVPGKPMCVE-----SFSDYPPLGR-FAVRV
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 206)

KTHINIV-IVGHV-
DSGKST-S--TGHLIYKCG-GINKR--SIKKFEKKA-AEMGKGSFKYAW---VL-----D
KL-KAECECGI--TI-HTSLWK-----FETS--KSFVCDSSWYTP-----GHRDFITNIF
T----G-TSQAD-CAVLV-VAA-GVGEFEA------------------------------
-----------------------------------------------------------K
R----YEEIIK-------EKT-GYNP--DTVAFVPISGWNSDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------ETV------------------------
-----------------------VLKPG--V-VITFAPVNT-TTEVKSVEIHHEAL----
----SE--AFSGDNVGFH-VK-----NVPVKDIHCGNNAGNC------------------
------------

PF03143 // ENSGT00910000144046_0_Domain_1 (553, 707)

-QVSAGYAPVLD--------------------CHMAHIACKF-AELKE
KTDRSSGK-KLEDGPKFLKS--GDVAIIYMVPGKPMCVE-----SFSDYPPLGC-FAACD
MRQT-VA---------------------------------V--GVIKAADKKAAGAGKVT
KYPQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEPERGI--TI-DISLWK-----FEIS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VTA-GVGEFEAGI---------SKNKQT-------------
-----------------QEHALLA-YTLGVKQLIVGVN--------KMDFTEPPYS--QK
R----YEEIIKE-VSTYIMKI-GYNP--DAAAFVPISGWNGDNMLE-PS-----------
------KVT-RKDGNSGGTTLL-----------EALDC---ILPPTHPTDKPLHLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--I-VVTFAPVNV-TT-VKSVEMHHEAL----
----SE--ALSGDNVGFN-VK-----NMSVKDVHRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNDP---GQISADYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDAPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPLLGC-FCSGM
I-SA-HC---------------------------------N--LCLPGSGDSP--A---S
AS----------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 348)

KTHINIL-VIRHV-
DSGEST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
EL-KAKRERGV--II-DISLWK-----FETS--KYYVT--IIDAQ-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VNTYIKKI-GCNP--DTVAFVAISGWNGDNILE-LS-----ANM-PW
-FKGW-KVT-SKDGNASRTTL-----------------------------------LE-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TNEVKSVEMHHEAL----
----SE--PLPGDNVGFN-VK-----NVSVKDARRGNVAGDSKND-L-PM---E-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 709)

AAGFT
AQVIILNHP---GQI----TPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDSPKFLKS--GDAAIVDMVPDKLMCVE-----SFSDYPPLGR-FAVHV
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DWGKST-T--TGHLIYKCG-GINKR--TIEKFEKEA-AEMGKRSFKY-------------
------RERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHGDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YPLGVKQLIVGVN--------KMDSTEPPYN--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLQPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

IAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQVSAGYAPILD--------------------CHMAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FTVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------IGKEKTHINII-VTGHC

PF00009 // ENSGT00910000144046_0_Domain_0 (60, 294)

-
G-------------------GIDKR--TIEKFEKEA-AEVGKGSFKYAW---VL-----D
KL-KAKRERGI--TI-DISLWK-----SETS--KYYMT--IFNAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEF--------------------------------
---------------------------------------------------EPPSS--QR
R----NKKIVKQ-VSTYIKKI-GYNH--DTVNFVPISGWNDDNILE-P------------
---------------------------------------------------------S-D
IYK----IGGI-DTVSMGQAETGILKPG--M-VATFAPVNV-TTEVKSVEMHYEAL----
----RK--ALPGDNVD----------------VCHGNVAGDSTND-P-LM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQIGADYASVLD--------------------CHTAHIACKF-AELKE
KIDYRSGK-KPEDGPKFLKA--GDAAIIDMVPGKPMCVE-----SFSDYPHLGC-FAVRD
MRHT-AA---------------------------------M--GVIKAVDKKAAGAGKVT
KSAQKAHKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
---------------------------------------MDKGSFQEAC---VL-----D
KL-K-----

PF00009 // ENSGT00910000144046_0_Domain_0 (130, 402)

-SGITT-NTFLGK-----PEAS--QSYMP--IIDAP-----GDTDFIKNMA
-------------------VAA-GVGEFEAGI---------SKNGQT-------------
-----------------HEHDLLA-DT-GCGMTNCSVD--------QVDSTEPPYS--QK
R----KE-TAKQ-VSTYIKKV-GYNP--HRVAFVPISGWNGDTVLA-PS-----ANR--W
------RVT-HKDGNIRGITWL-----------EALDS---ILPPTTCSADKLCLLFQ-D
VYK----IVGT-S-TVLGAEETSVLKPG--M-EVTFAPASI-IIEVKSVGMHHEAL----
----NE--APSGDNTDFS-VE------------HHDNVAADSK------M

PF03143 // ENSGT00910000144046_0_Domain_1 (531, 660)

PIKE-ATGLI
AQVIIMNHL---GQISTGHAPVLG--------------------CHPAHTACTF-AEPK-
RLNHCSSK-KLEDGPKLLKS--GADAITDIVPSKPMYVE-----SF--SPPLGR-FAISD
EA----------------------------------------------------------
------------------------------------------------------------
----------------------------------------

---------------------------------------MGKEK--

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

-THINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEXXXXXXXXXX---XX-----X
XX-XXXXXXXX--XX-XXXXXX-----XXXX--XXXXX--XXXXX-----XXXXXXXXXX
X----X-XXXAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------K

PF00009 // ENSGT00910000144046_0_Domain_0 (129, 404)

HGI--TI-SISLWK-----FETS--KYYVT--IIDAS-----EHRNFVKNVI
T----G-TSQAD-YAVLI-VAA-GVGKFET--------------EQT-------------
-----------------HKHALLT-YTLGVKQLIVGFN--------KMDTTEPPYS--QK
R----CKEIVKE-LSTYIKKI-GYNP--DAVAFVPISGWNGDNMLE-PS-----ADI-PW
-FKGW-KIT-CKDGNTSGTTLL-----------EALDC---ILPPTRPTDKPLWLPFQ-D
VYN----IGGI-GTIPVGRVETGVLKHG--M-VISF-------------EMHHESL----
----SE--ALPGDNVGIK-CQEPVCQRCSLGGVHCSNVAGDSKNG-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-APSFT
AQVIILKHP---GQISAGCAPVLD--------------------CHTVHIICKF-AELKE
KIDHQSDK-KLEDALKFLKS--ADAAIVDMAPGKPMCVE-----SFCDYPPLGH-FAVRD
MSQT-VA---------------------------------V--GVIEAVDKKAAGAGKVT
KSAQKAQKSK--------------------------------------------------
----------------------------------------

------------------------------------------MEKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHI-
DLGKST-T--TGLLIYKCG-GIDKR--TIKK-EKEA-AEMGKGSFKYAW---VL-----D
KL-IAECERDI--TI-DISLWK-----FETS--KYFVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VVA-GVGEFEAGI---------SKNEQT-------------
-----------------HEHVLLA-Y-----------------------------S--QK
R----YKEIVKE-VSTYIKKI-GYSP--DTLAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGVASGTTLL-----------EALDC---ILPPTCPADKPLHLPLQ-D
IYKKPLHLPGI-GTVPVGRVETGVLKPG--M-VITFAPVNV-TTEVKSVEIHHEAL----
----SE--ALPEDNAGFN-VK-----NISVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-ATGFM
AQVIILNHP---GQINAGYAPVLD--------------------CHLAHIACKF-AELKK
IDGH-SGK-KLEDGPKFLKS--GDAAIVDMVPGRPMYVE-----SFSDYPPLGH-FAVRD
MKQI-VA---------------------------------V--GVIKAVDKKAAGAGKIT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIRHV-
DSGKST-T--TGHLINKCG-GIDKR--TIKKFEKEA-AEMGKGSLKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVI--IIDAP-----GHRDFIKNTI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDSNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPT-----GVLKPG--M-VVTFAPVNV-TTEVKSIEMHHEAL----
----SE--ALPGHNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---K

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AHVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GNAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKGQTTKAKSED-----KRK---------KK--------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNI-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KIDRRSGK-KLEEGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-TM--L
S-IL-H----------------------------------------ASLICSSK------
------------------------------------------------------------
----------------------------------------

-------------------------------------------GKEKTHINIV-VIGHV-
DSGKST-T--TRHLIYKCG-CIDKR--TTEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAE-----------------------SE--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-SVGEFEAGI---------SKNGQI-------------
-----------------CEHALLA-YTLGMKQLIVGVN--------KMDSTEPPYN--QK
R----YEEIVKE-VSTYIKKI-GYKP--DTVAFVPISGWNGGNMLE-PS-----ANM-PW
-FKGW-KVT-REDVSASGTTLL-----------EALDC---ILLPSNPIDKPLSLPIQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 507)

GTVPVGRVETAVLKPD--M-VVTFAPVNV-TTEVKSVEMHQEAL----
----SE--ALPGDNVGFN-VK-----

ENSGT00910000144046_0_Linker_0_1 (507, 536)

NV--------------SND-P-PM---E-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 709)

AVGFA
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHVACKF-AELKE
KIDRLSGK-KLEDGPKFLKS--GDAAIVDM--------------SFSDYPPLRR-FAVRN
MRQT-VA---------------------------------V--GVIKVVDKKA-AGAGKK
AQKAK-------------------------------------------------------
----------------------------------------

------------------------------------------MGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 404)

MHINIV-IIGHV-
DSGKSI-T--TGHLIYKCG-VIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYMT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLL-VAA-GVGEFEAGI---------SKDGQS-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPCS--QK
I----YEEIIKE-VSTYIKK---------IVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPATRPTDKPLHLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNI-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAAFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KIDRHSGK-KLEDGPKFLKS--GDAAIVDMVPGKLMCVE-----SFSDYPPLGR-FAVCD
MRRT-VA---------------------------------V--GVIKAVDKKAVGAGKVT
KSAQYAQKLK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KIT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKRAGGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKENM

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 404)

HINIV-VIGHA-
DSGEST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAL---VL-----D
KL-KAEREHGI--TI-DISLWK-----FETS--KYYIT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGIN--------KMDSTEPPYS--QK
K----YQEIVKE-VSTYIKKI-GYNP--DTVAFVPISGCNGDNMLE-PS-----ANM-LR
-FKGW-KVT-CKDGNASGTTLL-----------EALDC---ILPPARPTDKPLRLPLQ-D
VYK----IGGI-GTVPVSQVETGVLKPG--M-VVTFAPVN-------SVEMHHDAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVCRGNVIGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 610)

-AAGFT
PQIIILNHP---GQISAGYAPVLD--------------------CHTAHIAWKF-AELKE
KIDHHSGE-KL-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTHPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 529)

AGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
---------------------------------------V

PF00009 // ENSGT00910000144046_0_Domain_0 (101, 407)

GRGSLKDPW---VL-----D
KL-KAEREHGI--TI-DISLWK-----FETT--KYYVT--IIDAP-----GHRGFI-NMM
A----G-SSQAD-CAVLI-VAT-G-----VVI---------SKNEQT-------------
-----------------HEHALLA-YTLRVKQLIVSVN--------KMDSLGPPYS--QK
R----CKKLLRK-SVLNIKKI-GYKS--NTVASVPVSDWNGDNRLE-PS-----ANK-PW
-FKV----ATYKDGNASGTTPL-----------EALDC---ILPPCHPTDKPLCLPLQ-D
IYK----IGG--GTVPVGPVKTGVLKYS--V-VVTFVPVKV-TTEVKSVEMHHETL----
----RE--FLPGDNVAFN-VK-----NIAVKDICRGNVAGDSKNN-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

IM---E-AAGLM
AQVIILNHP---NQ--AGYTPVLD--------------------CHTAHIACKV-AELKE
KFDRHSGK-KLEDGPKSLKS--HDAAIIDSVPGKP-CVE-----S---ISPLGR-FTVHD
MRHT-VV---------------------------------V--SVIRAIDKKAVGAVEVT
KSAQKAQKFK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------KKI-GYIP--DTAAFVPISGWNDDNMLD-PS-----ANM-SL
-FKGW-KVMSSKDGSASGSILL-----------------------------------E-D
VYK----IGGI-GTVSVGQMGTGVLKPG--M-VVIFALVNV-ITDIKSVEMDHETF----
----SE--ALPGDNVGFN-VK-----NVSVTDVRCVKLSGDSINV-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 663)

-GADFT
AQVIILNHP---GQISVGYAPVLD--------------------CHTAHIVSKF-SELKE
KIDRRSGK-KLKD------------AIIDMVPGKPVYVD-----SFSDYPPLGH-FAVCD
MRQR---------------------------------------GAIKAVDRKAAGAGKVT
NSAQKAQKVKC--IIL-LLPVTP--GLISGGR----------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-IIGH--
---------------------------------KEA-AEMGKGSFKYAC---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YILGVKQLTVGVN--------KMDSTEPPYN--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
IYK----IGGI-D

PF03144 // ENSGT00910000144046_0_Domain_0 (434, 518)

TVPVGRVETSVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPRDNVAFN-VK-----NVSVKDVHHGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 662)

-AAGFT
AQVIILNHP---GQISTGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MR----------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-V----------------IAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-SKDGSASGNTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGSN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFI
AQVIILSHP---GQISAGYAPVLD--------------------CHTAHIACKFFAELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VD---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 259)

TPINII-ITGHV-
DSGKAT-T--TGHLIYECG-GIDKR--TIEKFE-EA-AEMGRGSFKYAW---VL-----D
KLK---------------------------------------------------------
------------------------------------------------------------
-----------------NEHAPLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----D-------VTTYVKKI-GYNP--DTAASVTISGWNGDNMLE-PS-----ANM-PW
-FEGW-KVT-RKDGNASGT-LL-----------GALDC---SLPLPRPTDKPLHLPLQ-D
VYK----IGGI-GTVPGGQVETGVLKPG--M-VVTFAPVNV-TTEIKSVEMHHEAL----
----SE--ALPGYNVGFN-VK-----NVSVKDVRRGNVPSDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQAISLNHP---GQISAGYAPCWI--------------------V-TQLIACKF-AELKE
KIERCSGK-KLEDGPKFLKS--GDAAIVDMVPGKSMCVE-----SFSDYLPLGC-FAVHD
MRQK-VA---------------------------------V--GIINAVDKKASGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGNEQTHTNMV-----V

PF00009 // ENSGT00910000144046_0_Domain_0 (60, 345)

-
DLGKCT-T--TGHLVYK-------R--TPEKFETKS--A---RRGKYAW---VL-----D
RL-EAERERG--VAI-HLSPWK-----SETG--NHYVT--IADTP-----D-RDVIRNVI
P----G-TSQAN-RAMLIAAAA-ALGEAEAGS---------SKNGQT-------------
-----------------LLAYTL-----GVKQLTGGVN--------KVDSTEPPSS--QK
R----YEEIVKE-VSTYIKKF-GCNP--ETVAFVPISGWNGDNMLE-PS-----ANV-P-
-CKGW-QVP-HKDGSA------------------GTYC---WK-PWVPLTSYKS-APA-G
CLK----AGGI-GTVPV----TGVLTPG--K-GVTFLPVNG-TAEVKSSEMHHKAL----
----SE--ALPGDNVGFN-AK-----IVSVKHVHRGKV--------P-KMPTSG-S

PF03143 // ENSGT00910000144046_0_Domain_1 (537, 708)

SGFT
AQVIILNHP---GQISAGYTPVLE--------------------CHTAHIACKF-AELKE
AIDCHSGE-KLEEGPKFLKL--GDAAIV--VLGKPTCIE-----SFSDLL-LGR-FAVRV
--RT-VA---------------------------------V--GVIKAADEKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IVDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTKPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 707)

-AAGFT
AQVIILNHP---GQISAGYVPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FA--V
R-DM-R----------------------------------------KHYPTICCLQEIHF
T---CQDS--YTPKVKRR------------------------------------------
----------------------------------------

------------------------------------------MGKENTP

PF00009 // ENSGT00910000144046_0_Domain_0 (50, 345)

ITVV-VIGHV-
DSSKCT-S--TAHLIYRGD-GNNKR--TIEKSEKTA--EMGN-----AL---VL-----D
KL-KADSEH--G--I-PIDIWK-----SQTS--QYYVT--IIDAP-----IHRDLIKDTI
T----G-THQAN-C-----------VGFEAVI---------SKNGQA-------------
-----------------CEHAL-V-YTLDVKSLIVSVN--------QMDPTEPPYS--QK
R----YKENIKE-VNTYSKEI-GDNS--DVVAFVPISGWNGDNILQ-PS-----SNM-LW
-FKGW-KVS-EEV-----VAML-----------EEPQCHILILPPTHPAGKPLCLPLQ-E
V-Q----IGDI-GAVPVSRVEIGILKPG--M--GVSAPVSI-TMEVKSVEMHHKAL----
--------TLPGDHVGSN-VK-----NVVCLRSSYGNVSSDSKS--P-PV---E-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 660)

AGVFT
AQVRILSHA---DQISAGHVLVLH--------------------CCTAHITCKF-AELEA
KIDCCSVK-KLEGGPKVLKS--GDAVITDRIPGESMPSE-----SFSRAPSLGH-FAVHD
VR----------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 322)

KTHINII-VIGHV-
DSGKST-T--TGHLIYKCG-VIDKR--TIEKFKKDA-AEMGKGSFKYAW---VL-----D
KL-K-------------------------TS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------GEHALLA-YTLGVKQLIHYI-----------------------
-----------K-K-------IGYNP--DIVAFVPISGWNDDNMLE-PS-----ANT-PW
-FKGW-KVT-GNDGNASGTTLL-----------EALDC---VLPPTGPTDKPLCLLLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNI-TTEVKSVKTHHEAL----
----SE--ALPGDSVGFS-VK-----NVFVKDVRHGSVAADSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGLT
AQVIIWNHS---GQISTGHAPVLD--------------------CHMAHIACKF-PVQKE
KIDRHSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFPDYPPVGR-FAT--
-----VA---------------------------------M--GVIKAVDKKAAEAGKVT
KPAQKAQKAKRTLSVIP-ATL--VFL-ISHGRTVSELFVSIGH--LSLIVKDWLMITMHR
KIFRRKEECFVDHFGFILVCVAVLNY--------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDRPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEDKSAEIHHEAL----
----SE--ALAGDNVGFS-VR-----NISVKDVRHGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 666)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AEKLK
KIDRRSGK-KLEDGLKFLKS--GNAAIVDMVPGKPMCVE-----SFSDDMRQTV-AVGVI
K-AV-D----------------------------------------KKAPGTGKVTKS--
----AQ----KAQKAK--------------------------------------------
----------------------------------------

------------------------------------------SRKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 402)

KTHINII-VIGHV-
DSGRST-T--TGQLVYKRG-GINRE--QWKSLKNRL-P-GWKGSFKYAW---VL-----D
KL-KADRAWYH--HC-SLSLWN-----SETS--KCCVT--IIYAP-----GHRDFIKNVI
T----G-TSQAD-CAVLL-LLL-E------------------LSWQT-------------
-----------------REHALLA-CTLGVKQLIVGV---------KMDSTEPPYI--QK
R----HEEIVKE-VSAYIKKI-GRSP--NTVAFVSVSAWNGDNMLE-PS-----ANRPSW
-FKGW-KVT-RKDGTVQGTTLL-----------EALEC---ILPPTHPTDRPLRLRLQ-D
VYK----VGGI-GTVPVGHMETDVLKPG--M-MVPFAPVNV-TTEVKSSEMHHEAW----
----SE--ALPGDNVGFH-VK-----NVSVKDVRHGNMAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 701)

-E-AAGFT
AQLIILNHP---A----GYASVLD--------------------CHTAHIACKF-AELKG
KLDHCSGK--LEDGPKSLKS--SDATIIDMVPGKPMCVE-----SFSD-PPLGC-FAVRD
MRQT-VT---------------------------------V--VVSKAVGEKAAGAGEVT
KSAQNAQKAR--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 380)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAQ---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIAGVN--------KVDSTEPPHS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------------------------------E-D
VYK----IGGI-GTVPVGRVETGALRPG--M-VVTFAPVNV-TTEVKSVEMHREAL----
----SE--ALPGDTVGFS-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MKQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--NTVAFVPISGWNGDNMLE-PS-----ANM-PW
-F-GW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIIDMVPGKPMCVE-----SFSDYPPLGC-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

--------------------------------------------KEKTHISIV-VI----
----ST-T--TGHLIYKHG-GIDKQ--TIEKFENKA--A---EIFKYAW---VL-----D
KV-KAESECEHGITI-DISHKY-----DVTI--T----------------D-V-YL-R-M
N------DY-A--VL-IV-AA--GV-D-EF-QA-GI-SK-NW-QT-R-------------
------------------EH-AL--LA--YT-L-AE-PT-YR-QR-RY-EE-IV-K-EV-
R----T-YI-KK-IG-YH-S--DI-VV-WK-F-TR--KD-GS-A-S-G------T-----
------TLL------K------------------ALDC---VVPPTRPTDKPLRLPLQ-D
VYK----IGGL

PF03144 // ENSGT00910000144046_0_Domain_0 (432, 518)

-GTV-S----TGVLKPG--M-IVTFALVNA-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFS-VK-----NLSVKDIRCGS

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKNG-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-VAVFT
AQEIILNYP---GQISAGSAPVLD--------------------CHTAHIACKF-SELKE
KIDHHSGK-KLKDDPKFLKT--GDAAIIDMVP-----VE-----SFSDCPPLGC-FAVQD
MRQA-VA---------------------------------L--GIIKAVEKKTAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-V----------------IAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVL--K--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 543)

VAGDSKKD-P-PM---E------
A-

PF03143 // ENSGT00910000144046_0_Domain_1 (543, 709)

VIILSHP---GQISAGYAPVLD--------------------CHTAHIACKFFAELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 653)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGP-LV--A
C-TC-S----------------------------------------LSYT---------G
GWGKIIT-----------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKHAW---VL-----D
KL-KAERDPGI--TT-DISLWK-----FETS--KYYVT--IIDAP-----GHRGFIENMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLT-YTLG-K-----------------------------
R----YEEIVKE-VSTYIKKI-GYNP--ETVSFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGHVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRS------DGPKFLKS--GDAAIVDMVPGKPMCVK-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------LGKEKIHINII-VIGHV-
DSGKST-T--AGHLIDKCG-GTNKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEHERGI--TV-DISLK-------------DYVT--IIDAP-----GHRDFIKNMI
T----G-TFQAD-CVVLI-VAA-DVGEFKAGI---------SKNGQT-------------
-----------------REHALLS-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANV-PW
-FKGW-KVT-HKDGNASGTTLL-----------EALEC---ILPPTCPTDKPLWLPLQ-D
VYK----IGII-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--I-VVTFAPVNV-TTEEKSVEMHHEAL----
----SE--ALLDDNVGFN-VK-----NVSVKDVQRGS

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 638)

-AAGFT
AQVIILNHP---GQISASCAPVLD--------------------CHTAHIACKF-AELKE
KIDCRSGK-KLEDGPKFFKS--GDAAIVDMAPGKPMCV----------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------NT--VIVAFVPISGRNGDNIQG-PG-----ANM-LW
-FKGW-K-----DDNAGGITLL-----------EALDC---ILPPIRLANKPLHRPLQ-D
VYK-----GSI-GT

PF03144 // ENSGT00910000144046_0_Domain_0 (435, 513)

IPM-----GILKPS--L-VVIFVPVNV-PTEVKSVEMHYEAL----
----SE--AFPRDNVGFN-VH-----NVPIKD

ENSGT00910000144046_0_Linker_0_1 (513, 529)

VHHDTVASDSK-D-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PT---E-AAGFT
AQMIILNHP---GQISAGYAPAME--------------------RHPAYTACKF-AEQKE
KIGHCSGK-KMEADPKFLKS--GDAAFIDVAPGKPMGVE-----SYSDSLSLGR-CPLSD
VRQA-VA---------------------------------V--GVIKAVDKKAAGAGKGT
TSPRKVQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----RNCEHGIVSLI-DISLWK-----FEAS--KYYVM--IIDAP-----RHTDFIKNMI
T----G-ASQAD-CAVLI-VAA-GVGWYL-------------QNEQT-------------
-----------------REHALLP-YTLGEKQLIVGVN--------KMDSTKPPYS--QK
R----YEEIVKE-VSTYIKKT-GYNP--DTGAFVPISGWNGDNML---------------
---GW-RVT-CKDGGASGTTLL-----------------------------------K-D
IYK----IGGI-GTVPVGRVET----

PF03144 // ENSGT00910000144046_0_Domain_0 (447, 518)

AG--M-VVTFVPVNV-STEVKSIEMHHEAL----
----SE--ALPGDNVGFS-VK-----NVSVKDIKRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDGQND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 708)

-AAGFT
ARVIILNHA---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDCCS-------GPKFLKS--GD---------APMCVE-----SLSDYPPMGS-FSVHD
MRQT-VA---------------------------------V--GVIKAMDKKAAGAGKVT
TSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------NNNNMLE-PS-----ANM-LW
-FKGW-KVT-RKDGHAAGTMLL-----------EAVVC---ILLPTHPTDKPLCLALQ-D
VYK----TGGT-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 515)

GTVPVGRVETGVLKPS--M-VVACAPLNV-TTEVKSVEMHHEAL----
----SK--ALPGDNVGSN-VR-----NMSVKDVL

ENSGT00910000144046_0_Linker_0_1 (515, 529)

CGNAAGDSKSD-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PV---E-AAGFT
AQVIILSHP---GQISAGDAPVLD--------------------CHTTHTACKF-AELKE
KIDHRSGK-KLEDGPTFLKS--GDAAIVDVVPGKPMCVE-----SF-DYPPLGR-FAVHD
MRQT-VA---------------------------------V--GVIKAWTRRQLE-LAVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
-------------------------------WTTDL-LHASEST----------------
----TLSQNLQ--LW-EETFFL-----TSSE--YQCIE--NAG

PF00009 // ENSGT00910000144046_0_Domain_0 (164, 404)

TT-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRDNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEAGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 345)

KTHINIV-IIGHV-
NSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFTYAW---VL-----D
KL-KAERERGI--AI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VVA-GVGEFETGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-------KI-GYNP--DAVAFVPISGWNGDNMLE-PS-----ANM-PW
-LKGW-KVT-HKDGNASGTT----------------------------------------
---------------------LGVLKPG--M-VVTFAPVNV-TTEVKSVELHHEAL----
----SE--ALPGDNVDFN-VK-----NVSVKDVHRGNVAGDSKNN-P-PV--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AADLT
AQVIILNHP---GQISTGYAPVLN--------------------CHTAHIACKF-AELKE
KIGRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHV-
DLGKST-A--TGHLIYKCG-GIDKR--TLKKFEKEA-AEMGKGSFRYAW---VS-----D
KL-KAEHERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGVN--------KMDSTELPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVSISGWNGDIMLE-PI-----------
--------T-RKDGNASGTTLL-----------EALDC---ILPPICPTDKPLHLPLQ-D
VYK----IGGI-GTVP-----TGVLKPS--M-VVTFAPVNV-TTEVKSVEIHHEAL----
----RE--ALPGDTVGFN-VK-----HVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------YHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKATGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-IVGHV-
DSGKST-T--TDRLIYKCG-GINNR--TVEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEREHGI--TI-DISLWK-----FETS--KYYVT--IIGAP-----GHRDFIKNVI
T----G-MSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KTDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-G------TVVFVPISGWNGDNMLD-PS-----ANT-PW
-FKGW-KVT-RKDGNASGTMLL-----------EALDC---ILPPTRPTDKPFCLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTLPVGRVETGALKPS--M-VVTFAPVNV-TTEVKSVKRHHEAL----
----SE--ALPGVNVGFN-VM-----NVYVKNVRCGN

ENSGT00910000144046_0_Linker_0_1 (518, 536)

VAGDT-------------

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 709)

-ADFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDCHSGK-KLEDGPKFLKS--GDAAIVDKIPGKPTCVE-----SFSDYPPLGH-FAVRD
MRQT-VA---------------------------------V--DVIKAVDKKAAGAGKVT
KSAQKAQKPK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DLGKST-A--TGHLIYKCS-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-V----------------IAFVTVSGWNGDNMPE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNI-TTEVKSVKMHHEAL----
----NE--ALPGDNVGFS-VK-----NVSVKDDRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIAGKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGEEKTDNNIV-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-K

PF03144 // ENSGT00910000144046_0_Domain_0 (368, 520)

VT---------------------------------------------------
-------------------------KPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----GFSDCPPLGH-FAVCD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--LKAEHEC-------D

PF00009 // ENSGT00910000144046_0_Domain_0 (138, 598)

IALWK-----FETS--KYYVT---TDAP-----GHRGFIKNMV
V----A-HIRV--TAVLI-AAA-VVGEFEAGT---------SKHGQN-------------
-----------------CEHALLA-YTLGVKQLIVGVN--------KMDSTETPYI--QK
K----YEEIAKE-VSTSITKI-GYKP--DTVAFVPIS-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------VHTACKF-AKLKE---NHSGE-KLETGPKFLKS--GDAAIVDVVPGKPMCVH-----SCSDCLPLA--FAVCSIRQT-VA---------------------------------V--GVIKAVDEKAARTDKVTKSAQKAQKAK-------------------------------------------------------------------------------

PF03143 // ENSGT00910000144046_0_Domain_1 (587, 709)

-VHTACKF-AKLKE
---NHSGE-KLETGPKFLKS--GDAAIVDVVPGKPMCVH-----SCSDCLPLA--FAVCS
IRQT-VA---------------------------------V--GVIKAVDEKAARTDKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKT

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 206)

RINIF-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAEHERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEPPY---------S------------------
-----------------------------QK-----------------------------
R----YEEIVKE-VSTYIKKI-GYNP--DTVVFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGSI-GTVPVGQVDTGVLRPG--M-VVTFAPVNI-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-R-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACNF-AELKE
KIDRHSGK-KLEDGSKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 529)

AGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

-----------------------------------SLFLKAKMGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 345)

KAHINTV-VIGHV-
DSGKST-T--TSHLIYKCN-GIDQR--TIEKFEKEA-AEMGEA-----------------
------------------SFKK-----YETS--KYYVT--IIDAP-----GHRDI-KNMI
T----G-TSQAD-CAVLM-VAA-GAGEFEAGI---------SKNGQT-------------
-----------------HEHALLA-YTLGVKQLIVGIN--------KMDSTEPPYS--QK
R----YEEIVKE-VSSYIKKI-GYNP--DTVAFVPISAWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-HKDSNASGTTQL-----------EALDC---ILPPIRPTDKPLHLPLQ-D
VYK----IDGI-GIVPVGL--------G--M-VVTFAPINV-TTEVKSVEMHHEAL----
----NE--GLPGDNVGFN-IK-----KVSVTDVRRDNVTGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-A-AAGFT
AQVIILNHP---GQIRAGYAPVLD--------------------CHTAHFACKF-AELKE
KIDSHSDK-KLEDGPKFLKS--GDGAIIDMVPGKLMCDE-----SFSDYPPLGC-FAVRD
MRQM-VA---------------------------------V--GVIKAVDKKAVGAGKIT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 533)

AGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 616)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPDVSPL--GLCG---------FCLV--------GFPFLYL-SL--H
L-C--A----------------------------------------KVAV----------
-------I----------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKSA-T--TGHLMYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKN--
--------MIAD-CAVLI-VAS-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYQ-SQK
R----YEEIVKE-VSTYIKK---------IVAFVPISGWNGDNTLE-PS-----ANM-TW
-CKGW-NVT-RKDGSANGTTLL-----------EALDC---ILPPTRPTDKPLRLPLR-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 508)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----N

ENSGT00910000144046_0_Linker_0_1 (508, 535)

V--------------KND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 654)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AEIKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGQ-SISVV
MPKA-RT---------------------------------H--THTHTYPHTHPHPHTPY
GLRIIPIISGVM------------------------------------------------
----------------------------------------

---------------------------------KPPLNLN-QNGKGKD-SHIV-LIGHV-
DSGKST-T--TGHVIYKQN--------NIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAKRERGI--TT-DNSLWK-----LETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------CKNRQI-------------
-----------------CEHGEYV-YTLSIKQLIVGIN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVALVPISGWNGDNMLE-PN-----ANM-PW
-FKG----------------------------------------PTHPTDKPLRLPLQ-D
VYK----IDGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVFKPG--M-VVTFAPVSV-TSEVKSVEMH-EAL----
----SE--ALLGDNVGFN-VK-----NVSAKDVRHGN

ENSGT00910000144046_0_Linker_0_1 (518, 529)

VAGDS-ND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 708)

PM---E-TAGFT
AQVIILNHP---GQINAGYTPVLD--------------------CHTAHIACKF-AELKE
KIDRHSGK-KLEDGPKFLKS--RDAAIVDMV-GKPMCVE-----SFSDHPPLGY-FAGCN
MRQT-VA---------------------------------V--GVIKAADKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEE

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 404)

THINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGFFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKK
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPLLGR-FL---
----------------------------------------------GLVACTCSPRNSGD
G---CGRTA---------------------------------------------------
----------------------------------------

----------------------------------------------------------V

PF00009 // ENSGT00910000144046_0_Domain_0 (60, 345)

-
ESGKST-T--TDHLIYKRG-WVNKR--TIKKFEERL--LGGRGSFNYAC---VL-----A
AL-KAER--ERGVTI-EISLWK-----PETS--KHYAT--VTDAP-----GHRDSLQTMT
A----G-SSRAD-RAVPI-LAA-GVGEFQAGV---------SEDGPT-------------
-----------------RDLALLA-STPAVNQLTVGVR--------RMDST--------E
R----CEEIVKE-VSTSMKKT-GDT------ACVPISGWNGDNVLT-PR-----ANSTPC
VSEGW--KV-AKMGNAGGTALC-----------EAPDC---VSAT--DSSKALTLPLQ-D
VYK----IGAT-GSVPIGQIHQVITRAP--A-VLQ--------LRQSLLKRTIEAL----
----SE--ALPGDNVGFN-AK-----SVSVKDVCHGNVSGDSKSD-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 706)

-E-AAGFV
AQVIIPNRP---------YPSVWD--------------------MHQAHVVNKF-AELKE
ETDDHSGK-KLEDGPNS-KS--ADVAMIDMVPGKPMCVE-----SFSEYPPLGC-FAVGD
MREA-V-------------------------------------GVIKAVDKKAAGAGSWG
RHYVCREKLI--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINII-IIGHV-
DLGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGT-----------------D
KL-KAERERGI--TI-DISL-------------KYYVT--IIDAP-----GHRDFIINMI
T----G-TSQAD-CAVLI-VAA-GVGEFETGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YKEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-HKDGNASGTTLL-----------EALDC---ILPPTCPTDKPLWLPLQ-D
VYK----IGVI-S

PF03144 // ENSGT00910000144046_0_Domain_0 (434, 521)

TVPVGRVETGVLKPG--M-VVTFTPVNV-TTEVKSVEMHHEAL----
----NE--ALPGDNVGFN-VK-----NVSVKDVR------

ENSGT00910000144046_0_Linker_0_1 (521, 535)

RAKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 653)

-AAGFT
AQVIILSHL---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDCRSGK-KLEDSPKFLKS--GDAAIVDMVPGKAMCVK-----SFSDYPSLGG-LRCSR
--------------------------------------------------YETD------
-SCYGCHQSSGQEGCWS-WQGHQVCPESSEG-----------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHM-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW-----------
------RERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFNKNMI
T----G-TLQAD-CAVLI-VAA-GIGEFKAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIAKE-VSTYIKKI-GHNP--DTVAFVPISGWNGDNMLE-PS-----TNM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGIVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGC-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-IIGHV-
DSGKST-T--TGHLIYKCG-DIDKS--TIEKFEKEA-AEMGR----YSW---VL-----D
KL-KGKRERVI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNKI
T----G-TSQAD-CAVLV-VAA-RAGEFKADI---------SKNGQT-------------
-----------------CEHAFLA-YTL------------------------------GK
R----YEEIVEE-ASTYIEKI---------VAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-CKDGNASGTTLP-----------EALDC---ILPPTHPNDKSLRLPLQ-D
IYK----IGGI-S

PF03144 // ENSGT00910000144046_0_Domain_0 (434, 518)

TVPVGRVETGVLKPG--M-MVTFAPASV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-IK-----NVSVKDVHRGS

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAVDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVSILNCP---GQISAVYAPVLD--------------------CHTAHIACKF-AELKE
KIHRWPGK-KLEDGPKFLKS--GDAAIIDMVPGKPMCVE-----SFSDYPPLGR-FAVRS
MRQT-VA---------------------------------V--SVIKAVDKKGAGAVKVT
KCAHKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAKWMLSPIPAIPVLIS-----GGKTVSELFVSIGH--LSLIVKDWLMITMHR
KTFRRKGECFCGPYVLCVAV--------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 406)

KTHTNIV-VIEHV-
DSGKST-T--SGHLIDKCG-GVDQR--IMEKIEKEA-AEMGKGSFKDVW---VL-----D
KQ-K--AEHGT--TI-GISLWK-----SETS--KFVTI-----ID-----GHRDFIKNMI
T----G-T--AN-CAVPI-AAA-AVGEPEAGI---------PKNGQT-------------
-----------------REHALLV-YTLGVKQLMVGVN--------KMDSTESPYS--QK
R----YKEIV---VSTYIKKVSTYNL--DTVVYVSISGWNGDNMLH-PS-----ANM-PW
-FIGW-KVT-HKGGSANESKLH-----------ETLDR---ILALTYTTDKSLYLPV--E
LYK----ICGI-GTVSVSQLESGILKPG--I-VVTFAPINV-ITEIKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NESVKDVWCSNVVGDSKT--P-PM---E-VACST
AQVS-LKVP---G-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 345)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------QEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--NTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTPL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETAVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYVW---VL-----D
KL-KAKRERGI--TI-DISLRK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEA------------------------------
------------------EHALLA-YTLGVK-LIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--YTVAFVPISGWNGDNMLE-PS-----TNM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFA
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLSH-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKGQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKT

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 404)

QINVI-VIGHV-
DLGKST-T--TGHLIYKCG-GFDKR--TIEKFEKEA-AEMGKGSFKYTW---VL-----D
KL-KAEREHGI--TI-DISLWK-----FE-----------------------NNFIKNMI
T----G-TSQGD-CAVLI-VAG-GVGEFEAGI---------SKNRQT-------------
-----------------RKHALLA-YTLGVKQLIVGIN--------KMDSTEPPYS--QK
R----YEEIFKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVI-CKDGNASGTTLL-----------EALDC---ILPPTHPTDQLLRLPLQ-D
VYK----IGGI-GTVPEGRVETGVLK-----------PVNV-TTEVKSVEMHHEAL----
----SE--TPPGDHVGFN-VK-----NVSVKDVHCGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 618)

-AAGFP
AQVIILNHP---GQISAGYAPVLD--------------------CHTTYIACRF-AELKE
KIDRRSGK-KLEDGPKFLYL--VMLPSLTWFQASPC-VS-----RASLT-----------
------------------------------------------------------------
--------------IHL-WVVSLFML----------------------------------
----------------------------------------

---------------------------------KPPLNLNQN--GKGKDSHIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REYALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------WGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 402)

MHINIV-VIGHC-
-SGKST-T--TGHLIYKCD-GIDKR--TMETFEKEA-RVGVGKGSKCAW---VL-----N
KL-KADHERGI--TI-DTSLWK-----FETS--KYYVI--IIDAP-----GHRDFIKNMI
T----C-TSQVD-CAVLI-VAA-GVGKFEAGI---------SKNGQT-------------
------------------EHAVLA-YTLGVKQLTVGVN--------KMDSTEPPYS--QK
R----YEEIIKE-ISTYIKKM-GYNP--DIEAFVPVSGWNGDNMLE-PR-----A-----
--NGW-KVT-CKDGNTSGTTLL-----------EALDC---FLQPSRPTYKPLLLPLQ-D
IYE----IGGI-GTLPVGP-EEMVLKPG--M-VVTFAPVIV-TAE-----MHHEAL----
----SE--ALPGDNVGFN-VK-----NISVKVVHRGSVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 663)

-E-AAGFT
AQVIVLNHP---GI-SVGYASVLD--------------------CHTAHTACKF-ADLKE
KIDHHSGK--KENGLKFLKS--GDAAIVDMVPGKPLCVE-----SFSDYPPLGR-FAVCD
TRQL-LS---------------------------------V--SSKQGTRKQLELARNVC
VNWPCKLNSK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 661)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPP--L-GR--F
A-C--S----------------------------------------GTILANCNL-----
----CLLVSNDSPASAS-------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIL-VIGHV-
DSGKST-T--TGHLIYECG-GIDKR--TVKKFEKDA-AEVGKGSFKYAW---VL-----D
KL-KAECERGV--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-AAG-GVGEFEAGI---------SKNGT--------------
-----------------HEHALLAY-T----------------------------L--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVACVPISSWNGDNMLE-PS-----ANV-PW
-FKGW-KVT-RKDGNANGT-LL-----------EALDF---ILPPTR----PLRLPFQ-D
VYK----IGGI-GTVP-

PF03144 // ENSGT00910000144046_0_Domain_0 (438, 518)

GRMETGVLKLG--M-VVTFAPVNV-TTEVKSVEMYHEAL----
----SE--ALPGDNVGFN-VK-----HVSVKDVHCGN

ENSGT00910000144046_0_Linker_0_1 (518, 529)

VAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFM
AQVSILNHP---GQISARYAPVLD--------------------CHTAHIACKF-AELKE
KIDRCSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCIE-----SFSDYPPPGH-LAVCD
MRQT-VA---------------------------------V--GVINAVDKKAAGAGKVT
KSAQEAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-CKDGNASGTM

PF03144 // ENSGT00910000144046_0_Domain_0 (381, 518)

LL--------------------------------------
--------------------ETGVLKPG--M-VVTFAPVNV-TTKVKSVKMHHEAL----
----SE--AFPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-LM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KLIAIPVK-KLENGPKFLKS--GDAAIVDMVLGKPMCVE-----SFSDYPTLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSVQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

----------------------------------KPSLNLSQNGKGKDSYQYC-PQWTY-
RFR

PF00009 // ENSGT00910000144046_0_Domain_0 (64, 406)

KST-T--IGRLIYKCG-V-KKR--TLQKFEEAA-AEVGKGSLKYAW---VL-----D
KL---RIECEHIPTT-DITLWK-----LKTT--KYDVT--TTDNR-----GHTDFIKNMI
T----G-TSQAD-CALIV--AA-SVNELEARI---------SKNGPP-------------
-----------------REHALL--ITHRAEELTVDIN--------KMDPTEPPYG--QK
R----HKKSLRKSAP--TKKT-GYNC--NTVAFPPI-SWIGDSMLEETI-----ANM-PW
-FKEK--VT-CKDGSASGTTPL-----------EALDC---ILPPTHPTDKLLGLSLQ-D
MYK----TGGT-GTG---QVESGVSNPS--R-MGTFAPVNM-RSEVNSDEMQHEAL----
----SE--ALPGDKAGFS-VK-----NVSVKYVCCGDVTADSKSD-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 661)

MM---E-TGSFM
AQVINLNDP---GQVNAGYAPVLD--------------------CHTAHAACKF-AELG-
-------A-EREDGTKSLKS--GDS-IVDTIPDMLLCVE-----SFPDYPPLGH-FAVYD
M-----------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DTGKST-T--TGHLIYKCD-GIDKR--TIDKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TT-DTSLWK-----FGTS--KYYVT--IIDTP-----GHRDLIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------QEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEAIVKE-VSTYIKKT-GYNP--DTVAFVPISGWNGDNTLE-PS-----ANM-PW
-FNGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTHPTDKPLHLPLQ-D
VYK----IGGI-GTVP-----TGVLKPG--M-VDTFASVNV-TTEVKSVEMHHEAS----
----SE--ALPGDNVGFN-VK-----NVSVKDVRHGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 653)

-AAGFT
AQVIILNHP---GQVSAGYTPVLD--------------------CHTAHIACKF-AELKE
KIDCCSGK-KLEDGPKFLKS--GDAAIVDTVPGKPTCVE-----SFSDYPPLGL-SLCCS
GWRA-VA---------------------------------R--SWLTATSASG--FKQFS
CLSFPSS-----------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 333)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIEKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-V----------------IAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRHGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 658)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SVSDYPPLGR-FAVAV
G-------------------------------------------VIKAVD----------
--KKAAG----AGKGTKSAQKAQ---------KANDIIPNTCH--L--GLNQWWR-----
EANGLRTVCFNWPFKFSSKRLVNDNNAS------------

------------------------------------------MGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 334)

MHINIV-VIRHV-
DSSKST-T--TDHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKNAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYIT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNRQT-------------
-----------------REHAILA-YTLGVKQLIVGVN--------KTDSTEPPYS--QK
R----YEEIVKE-V----------------IAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-HKDGNASGTTLL-----------EALDC---ILPPTHPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVPFAPVNI-KAEVKSVEMHHE------
--------------------------NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYVPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDSPKFLKS--SDTAIVDMVPGKPMCVE-----SFSDYPPLGH-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 191)

KTHINIV-VTGHV-
DSGKST-T--TGHLIYKCG-SIDKR--TIGKFEKAA-AEMGKSSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVI--IID-----------------
----------AD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLV-YTLGVKQLTVGVN--------KMDSTEPPTS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTMLL-----------EALDC---ILPPTHPTDKPLHLPLQ-D
VYK----IGGI-GTVPVGRVETAVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGGNVGFN-VK-----NVSVKDVCHGNVAGESKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GHISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 321)

THINIV-VIGHI-
DSS---------------------K--T-----------IEKFEKEAAL---VL-----D
KL-KAEHERGI--TI-DISLWK-----FEII--S--------IPQ-----DTRDFIKNMI
T----G-TSQAD-CAVI--VAA-GVGEFEAGF---------SKNGQT-------------
-----------------REHALLA-YIWGVKQLVVGVN--------KMDSTD--------
---------------TYIKKI-GYNP--DTVTFV--------------------ANM-PW
-FKGW-KVT-REDSSASGTTLL-----------KALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVIFAPVNV-TTEVKSVEMHQEAL----
----NE--ALPGDNVVFN-VK-----NVSVKDIHCGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AADFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AERKE
KTDSRSGK-KLEDGPIFLKS--GDAAIVDMVPGKSMCVE-----SFSDYPPLDR-FAVCD
TRQT-VA---------------------------------V--GVIKAVDKKAAGASKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKI

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 345)

LINIV-IPGHV-
DGKIH----HYWPPVYKYG-GIKER--SKNF--EKEAVEIGKGSSESAQ---VL-----D
KM-KAECKHG--ITI-AISLWK-----FEIS--KCCVT---IDAA-----EHRYFIKNMI
T----D-TPQAD-CAVLI-IAA-GVGEFEAAI---------SKDGQN-------------
-----------------CGHALLA-YTLGMKQLIVGAN--------KMDSTGPHYS--QK
R----YEEIIKE-SSTYIKKI-GYDP--DTVAFVPISGWNGDNMLE-PS-----ANM-FW
-FKGC-KVT-HKNRNASELCCKKLWIASCYLLVQLANC---MSTKFMVLGLSLWAEW---
---------------------------R--L-VVSNQALW--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
NSGKST-T--TGHLIYKCG-GIDKR--TIEKFKKEA-AEMGKGSFKYAW---VL-----D
KL-KAERECGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKN----------------
------------------------------------------------------------
----------------------------------------GDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 519)

GTVPVGRVETGVLKPS--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNV

ENSGT00910000144046_0_Linker_0_1 (519, 529)

AGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHLACKF-AELKK
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAVGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MG-KK

PF00009 // ENSGT00910000144046_0_Domain_0 (48, 397)

TNINIV-ITGQV-
GSGKST-T--TGHLIYKCI-DIDKR--TIQKFEKEA-SDG--------------------
-----------------KGLLQ-----FETS--KYYVS--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------NEHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIIKE-VSTYIMKI-GCNL--DTVAFALISG---------PS-----ANM-PW
-FKGL-KVT-HKDGNTSGNSLL-----------EALDY---IVPPTHPTNKPFRLLLM--
STK----IGGI-GTVSVGCSKT-----------LYGAPVNV-TTEVKSVVIHHEAL----
----SG--ALPGDNVGFN-VK-----NVSVKDVRHGNNAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 707)

PT---E-AAVFT
AQVIILNYP---GEISAGYAPVLD--------------------YHTAHTACKF-AELKE
KIDHCSGK-KLEDGPKFLKS--GDVAIVYMVPGKPMCVE-----SFSDYPPLVH-FAVGH
MRQI-VA---------------------------------V--GIIKAEDRKAAGAGKVT
KSAQKALKPS--------------------------------------------------
----------------------------------------

-----------------------------------KPPLNLNQNGKGKDS

PF00009 // ENSGT00910000144046_0_Domain_0 (51, 396)

HIV-VTGHV-
DLGRST-T--IGHLIYKCG-RI-KR--TIEKFEKEA-SEMGKGSFKYAW---VL-----D
KL-KAEGEHGI--TI-GISLWK-----FKTS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHGLLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTCIKKI-GYNP--DTVAFVPISGWNGDNMLE-PI-----ANM-PW
-FKGW-KVT-RKDGNA--NTLL-----------GALDC---ILPPTRP-DKPLCLPLQ-D
VYK----IGGI-GTFP-GQVETGVLKPG--M-VVTFAPVNV-KIEVKSAEMCHEAL----
----SE--ALPRDNVGFD-VK-----NISVKDVRHGNVAGDSKSD-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PM---E-AAGFM
ARVNILNHP---GQISAGYAPVLD--------------------CHTAHIAGKF-AELKG
KIDCHSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGY-FAIRD
MRQM-VA---------------------------------V--GVIKAVDKKAAGAGKIT
KSAQKAQKTK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
---------------------------------------MGKGSFKYAW---VL-----D
EL-KAECERGI--TI-DISLRK-----FETS--KYYVT--IIDAP-----GHRDFIRNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKA-VSTYIKKT-GYNL--NTVAFVPISGWNGDNMLE-PS-----AKM-LW
-FKGW-KVT-HKDGNASGTTLL-----------EALDC---ILPPTRPNDKPLCLPLQ-D
DYK----IGGI-DTVP-----

PF03144 // ENSGT00910000144046_0_Domain_0 (442, 518)

TGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFS-VK-----NVFVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 587)

VAGDSKND-P-PM---E-AA---
----------------------------------------------

PF03143 // ENSGT00910000144046_0_Domain_1 (587, 709)

-AHIACKF-AELKE
KIDRCSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQI-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 301)

KTHINII-VTGHV-
DSGKST-T--TGHLIYKCG-VIDKR--TIEKFKKEA-AEMGKGSFKYAS---VL-----D
KL-K-------------------------TS--KYYVT--IIDAP-----GHRDVIKNMI
T----G-TSQAD-RAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLG------------------------------K
R----YKEIVKE-K-------IGYNP--DTVAFVPISGWNDDNMLE-PS-----ANT-PW
-FKGW-KVT-GNNGNASGTTLL-----------EALDC---VLPPTGPTDKPSCLLLQ-D
VYK----IGGI-GT-------TGILKPG--M-VVTFAPVNV-TTEVKSVKTHHEAL----
----SE--ALPGDNVGFS-VK-----NVFVKDVRHDIVAGDSKNE-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGLT
AQVTIRNHS---GQISAGYAPILN--------------------CHMAHIACKF-PVQKE
KIDRCSGK-KLEDGPKFLKS--GDAAIVDTVPGKPMCVE-----SFSDYPPVGR-FAVHD
LRQT-VV---------------------------------V--GVIKAVDKKAAEAGKVT
KPAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNIAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPP--L-GL--C
S-R--I------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIF-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAKRERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGT---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPXXXXXXXXXXXXX-X
X----YKIGGT-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVSVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSLEMHHEAL----
----NE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDXXXD-P-PM---E-AAGFT
VQVIILNHP---GQISAGYTPVSLIVKDWLMITMHRKTFRRKGECFVDHFLCVC-GSF--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-YISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IVGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVKMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRCGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 656)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FLRSC
CCTP-A------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 409)

KTHSNIA-IIR---
----HT-T--AGHLIYKCG-ELTKR--TIEKLEDGA--AMG-RSFKSAW---IS-----D
KL-KAA--WAQGLAI-DISLWF-----VT-S--KDYVT--VINPP------HRDFINNMM
T----G-PSQAD-GVSIT--AG-GVGEFEAAIA-------------P-------------
-----------------KEHVSLA-YTLGGKQLIVAVN--------KMDSTGPFYR---K
R----DEDIITD-VSTYFEKI-GYKP--DTGDFVSISGWKGSMLEP--S------AH-LW
-FNGW--VT-HKDGNASET-LL-----------DTLDC---IQ----STDKPLRPPLQ-H
IYK----IGGF-TPVPVGSVETGLLKPG--M-MVTFTPLKV-TTEVKAVEMRHKVL----
----SE--ALPRDNVGFN-VK-----DVSVKNVCRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 711)

PM---E-TAVFT
AQVIILSCP---GHISAGHMPVLD--------------------CHDAHL-AKF-AELKE
KIDCHSGK-KLEEGPRFLAI--FD-----TVPGKP-GVD-----SFSDYPPLGH-FAVRD
MRTA-A-------------------------------------VGVKAEDKKAAGAGKVT
KFAQ--------------------------------------------------------
----------------------------------------

------------------------------------------MGEE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 461)

KTHINIM-VIGHV-
DLGKST-T--TSHLIYKGG-GINNR--TTKKKNEKVAAEMGKGSFKYAW---FL-----G
KL-KAECECG--ITT-AISLWK-----LETS--KYYVT--IT-DP-----GHRDFIKNMI
T----G-ASQAD-CAALI-VAA-GVAEFEAGI---------SKNGQT-------------
-----------------HEHEC--------------------------------------
-----------------------------------------------DN-----TNM-PW
-FKGW-KVT-CEDGKATGTTLP-----------EALDC---ILPPARPVDKPCLPLPD-F
YKT-----GGI-GTVPVGEWRL-VLKPS--M-VVTFAPVNV-STEV-NSLGHHVVL----
----RD--ALPGDHVGFN-VK-----NVSVKDGHHGNVTGDTKMP

PF03143 // ENSGT00910000144046_0_Domain_1 (526, 710)

TN------G-IAGFT
TLIIILSHP---GQISAGCTPVLD--------------------CHQAHIACTL-TKQKT
TDD--------RSGPLSMVP------------GKPMCVG-----SFSDYPPLGH-ET---
-----VA---------------------------------L--GVIKAVDKKAAGAGKVT
TSAQKDQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKT

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 345)

RINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNS--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------E-----------------PLRVPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKMHINIV-VIGHV-
DSGKST-T--TGYLIYKCG-GINKR--TIKKFEKEA-AEMGKGFFKYAW---VL-----D
KL-KAERERGI--TI-NISLLQ-----LKKK--TTK-----------------HDSGT--
--------SQAD-CAVLI-VAA-GVGEFEAGI---------SKNRQT-------------
-----------------HQHALLA-YTLGVKQLIVCVN--------KMNSTGPPYS--QK
R----YKEIVKE-VSTYIKKI-SYNP--DTVAFVPISGWNGDNMLE-PS-----A-----
----------------------------------TLDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GI

PF03144 // ENSGT00910000144046_0_Domain_0 (435, 518)

VPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGS

ENSGT00910000144046_0_Linker_0_1 (518, 536)

VAGNSQND-P-PV---E-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 709)

APGFT
TQVIILNHP---GRISAGYAPVLD--------------------CHMAHIASKF-AELKE
KIDCLSGK-KLEDGPKFLKS--GDAAIIDMVPGKPLYVE-----SFSDYPPLGR-FAVCD
MRQT-VA---------------------------------G--AGKVTKSAQQAQKAK--
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKMHINII-VTGHV-
DSGKST-T--TGHLIYKCG-VIDKR--TIEKFKKEA-AEMEKGSFKYAS---VL-----D
KL-K-------------------------TS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-RAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KM----PPYS--QK
R----YKEIVKE-K-------IGYNP--NTVAFVPISGWNDDNMLE-PS-----ANT-PW
-FKGW-KVT-GNNGNASGTTLL-----------EALDC---VLPPTGPTDKPLCLLLQ-D
VYK----IGGI-GT-------

PF03144 // ENSGT00910000144046_0_Domain_0 (442, 513)

TGILKPG--M-VVTFAPVNV-TTEVKSVKTHHEAL----
----SE--ALHGDNVGFS-VK-----NVFVKD

ENSGT00910000144046_0_Linker_0_1 (513, 533)

VRHDNVAGDSKNE-P-PT--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGLT
AQVTIWNHS---GQISAGSAPVLD--------------------CHMAHIACKF-PVQKE
KIDRCSGK-KLEDGPKFLKS--GDAAIVDTVPGKPMFVE-----SFSDYPPVGR-FAVHD
LRQT-VV---------------------------------V--GVIKAVDKKAAEAGKVT
KPAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-IIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AELGKGSFKYTW---LL-----D
KL-KAEYECGI--TI-DIFLWK-----FETS--KYYMT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-AVDEFKAGI---------SKTGQT-------------
-----------------SEHALLA-YMLGVKQLIVGVN--------KMDSIEPPYS--QK
I----YEEIVKE-VSAYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVI-SKDSNANGTTLL-----------EALDC---ILPPTHPTDKPLQLPLQ-D
VYK----IGGI-STVPMGRVETGVLKPA--I-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NMSVKDVRHENVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIDCKI-TELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGH-FTVCD
MRQT-VA---------------------------------V--GVIKAVNKKAAGAGKVA
----------------KSAQKLR---------GLNEYHP---------------------
----------------------------------------

------------------------------------------VGKEKTHINIV-VIGHV-
DSGKST-T--TSHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAKCERGI--TI-AISLWK-----FETS--KYYVM--IID-----------------
----------AD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLV-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKT-GCNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-HKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLQLLLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--I-VVTFTPVNV-TNEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVHRGN

ENSGT00910000144046_0_Linker_0_1 (518, 533)

VAGGSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-TASFT
ARVIILNHP---GQISAGYAPVLD--------------------CHTAHIVCKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDA-------------------SFSDYPPLGH-FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKVQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLCK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVDVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLR--
------------------------------------------------------------
----------------------------------------DSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGE-KLEDGPRVLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLG--FAVHD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------III-DISLWN-----FETS--KYYVT--SNGAP-----GHRDFIKNMI
I----G-PYQAD-YAVLI-VVA-GIGEFEAGI---------SKNRQT-------------
-----------------HEHALLA-YMLDVKQLIVGNN--------KMDSTGPPYS--QK
R----HEEVVKE-VSTYIKKI-GYNP--DTVASVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-HKDGN------------------------------------LLWLTLQ-D
VYK----VGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 513)

GTIPVGTVETGVFTHG--M-VVTFAPDSV-TTEVKSIEMHHEAL----
----GE--ALPGDNVGFN-IK-----NVSIKD

ENSGT00910000144046_0_Linker_0_1 (513, 535)

VHHDNIACDSKTN-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 665)

-AAVFI
AQVIILNRP---GQISAGCAPVLH--------------------CHAVHITCKF-AELKE
KIDHCSSK-KLEDGPIFLKS--GDIAIMTWFQASPFVL----------------------
---RTVA---------------------------------V--VVIKAVDKKAAGAGKVT
KSAQKAEKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------KWR-----PA----

PF00009 // ENSGT00910000144046_0_Domain_0 (154, 396)

KRYGT--ILDAP-----GHEDYRRNNV
T----G-TSRAA-CAVLM-IAA-PAGDFEIGV---------SKNGQR-------------
-----------------QEHSLLA-CGTN------GVN----TLDSPKPSIPPR--PTPS
G----PEEIVRE-VSTYIKKI-GYNP--DTVAFVPISGWNCDNVQE-PS-----SNM-PC
-FKRL-TVL--------GTTLH-----------EALDC---TWPSKMSTKLS----V---
----------F-GTVPVSQVESGVLKLG--I-VIAFAPVNV-TNEVKSVEIYHEAL----
----CE--TLTEDYIGLD-IK-----NVFAVAII-------NKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFA
ALIIISNH----PPISAGYALVLH--------------------CHTVHIACES-AKLK-
-ID-CHSS-KKLEEPKFLKS--DAAAIVDMVPGQPMWVE-----SFSDYPPMGS-FAFHD
MRQT-VA---------------------------------V--GVIKAVDKIAAGAGKVT
KSAQKAK-----------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 345)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL--------------------------------------
--------------------ETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRHGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISA------------------------------AHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GGATIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------M--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------VGKEKTHINIV-VIRHV-
DSGNST-T--TGHLIYKCG-GINQL--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAE-----------------------RD--KYYVT--IID-----------------
----------AD-CAVLI-VAA-GAGEFEAGI---------SKNRQT-------------
-----------------HEHVLLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VITYIKKI-GYNP--DTVAFV--------------------------
---------------ASGTTLL-----------EALDC---ILSPTRPTDKPLRLPLQ-G
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 524)

GTVPVGRVEAGVLKSG--M-VVTFAPVNV-TTEVKSVELNREAL----
----SE--ALPGDNVGFN-VK-----NV------------DSK

ENSGT00910000144046_0_Linker_0_1 (524, 535)

ND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 662)

-AAGFT
AQVIILNHP---GQISAGYASVLD--------------------CHTAHIASKF-AELKE
KIDCLSGK-KLEDGPKFLKS--GDAAIVGMVPGKPMCVE-----SISDYPPLGR-FAVHD
MSCC-I------------------------------------------------------
------------------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTLINIT-VIGHI-
DLGKST-T--TDHLIYKCG-GIHKR--TIEKFEKEA-TEMGKGSFKYAW---VL-----D
KL-KAECERGI--TI-DISLWK-----FETS--KYYVT--IIDIP-----GHRDFIKNMI
T----------------------------AGI---------SKNGQT-------------
-----------------REHAFLA-YTLGVKQLIVGVN--------KMDSTKPPYS--QK
R----YKEIVKE-VSNYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-LKDGSASGTTLL-----------EALDC---ILSPTHPNDKSLHLSLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 489)

GTVPFGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMYHKAL----
----KH--

ENSGT00910000144046_0_Linker_0_1 (489, 535)

VCQ-----------------------RRSTWQCCKND-P-SM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---DQISAGYAPVLD--------------------CHTAHIACKF------
-INHHSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-LAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--IIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAD-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 657)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLAR-HS--L
C-CV-L----------------------------------------FIGVKSL-------
------LKMGSFPEK---------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-RAVLI-VHA-L------------------------------------
----------------------------------------------------LAYT--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANI-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----ISGI-G

PF03144 // ENSGT00910000144046_0_Domain_0 (434, 518)

TAPVGQVETGVLKPS--M-VVTFAPVNV-TTKVKSVKMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRCGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KLIAVPVK-KLENGPKFLKS--GDAAIVDMVLGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGNVT
KSVQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VTGHV-
DSGKST-T--TGHLIYKCG-GIDKR--IIEKFEKEA-AGMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DLSLWK-----FDTS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAG-CAVLI-VAA-SVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQQIVGVN--------KMDSTEPPYS--QK
R----YEEIVTE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLSLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPS--M-VVTFAPVNV-TTEVKSVEMHHEVL----
----NE--ALPGDSVGFN-VK-----NVSVKDVCRGN

ENSGT00910000144046_0_Linker_0_1 (518, 533)

VAGDSKNN-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
NIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPSKPMCVE-----SFSDYPPLGH-FAVRD
MRQI-VV---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--NI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------R-----------VKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWDSDNMLE-PS-----ANM-PW
-FKGW-KVT-HKDGNTSGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
AYK----IGDI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----KVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDCRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVN-----SFSDYPPLGC-FAVRD
MRQT-VV---------------------------------V--GVIKAVDKKAAGAGKVT
ESAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIENFEKEA-AEMGKGFFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VDA-GVGEFEAEH---------A------------------
---------------------LLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANI-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLHLPLQ-D
VYK----IGGI-GTASVGQVETGVLKPG--M-VVTFAPVNV-TTKVKSVKMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-LM---G-

PF03143 // ENSGT00910000144046_0_Domain_1 (536, 709)

AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHMAHIACKF-AELKE
KLIAVP-------------S--GDAAIVDMVLGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSVQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKT

PF00009 // ENSGT00910000144046_0_Domain_0 (49, 404)

HMNI--VIGHV-
DSGKST-P--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CALLI-VAA-GVGEFEASI---------CKNEQT-------------
-----------------HEHAHLA-YTLGVQQLILGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDDMLE-PS-----ANM-PW
-FKGR-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLSLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-ITEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRHGNVAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIVLNHP---GQISAGHAPVLD--------------------CHTAHIACKF-AELK-
KIDHRSGK-KLEDGPKFLKS--GDTAIVDMVPGKPMCVE-----SISDYPPLGH-FAVCD
MRQT-VA---------------------------------V--GVIKAVDKKEAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 403)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EVLDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVSVGRVETAVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 705)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVCD
MRQT-VA-------------------------------------VIKTVDKKAAGAGRVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKCAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLMVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DAVAFVPISGWNGDNMLE-PS-----ANM-PW
-FEGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVPRGNIAGDSKND-P-PM--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRHSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------WK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGL---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACRF-AELKE
KIDCRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGRVT
NSAQKARKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 345)

KTHIHIV-VIGHV-
DSDKST-T--TGHLNYKCG-SINKR--TIEKFEKEP-AEMGKGSFKEAW---VL-----D
KL-KAERERGI--TI-DTSLWK-----FENS--KCYMT--IIDRL-----NHRDFTKNMI
T----G-TSQAD-CAVLI-VAA-SVGEFE-------------------------------
------------------EHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIV-------KEKI-GYNP--DREAFVPISGWNGDNMLE-PS-----------
------------DGNTSGTMLL-----------E--------------------------
---------------------TGVLKPG--M-VVTFAPVNI-KTEVKSVEMRHEAL----
----SE--TLSGDNVGFN-VK-----NVSVKDVRHGNDAGDSKDD-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHTACKF-AELKE
KMDRHVGK-KLEDGPNFLNS--GDAANVDMVPGKPVCVE-----CFSDYPPLGR-AAVHD
MRQT-VA---------------------------------V--DVIKAVNKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MEKEKTHINII-IIGHI-
DSGKSSTT--TGHLIYKCS-GIDKR--TIKKFEKEA-AEVGKG-FKYAW---VL-----D
KL-KAEHKRGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDF-IKMI
T----G-TSQAD-SAVL--IAA-GVGEFEAGI---------SKNGTP-------------
------------------EHALLA-YTL------------------------------QK
R----YEEIVKE-VSTYIKKI-GYNP--NIVAFVPISGWNGDNM-E-PS-----ANL-PW
-FKGW-KVT-RKDGNASGTTLL-----------KALDC---ILPPTCPTDKLLRLPLQ-D
VHK----ICGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVEAGVLKPG--M-VVTFAPVNV-TTEVKSVEMYQEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRSN

ENSGT00910000144046_0_Linker_0_1 (518, 529)

VAGDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 709)

PV---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SVSDYPPLGH-FAVHD
MRQT-VA---------------------------------V--GVINAVDKKAAGAGKVT
ESAQEAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHIHIV-VIGNV-
DSGKST-S--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DLSLWK-----FETS--KYYVT--LTDAP-----GHGDFIKNMI
T----G-TSQAD-RAVLI-VAA-GVGEFEAGI---------SKSGQT-------------
-----------------HEHGLLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
G----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-HKDGNASGTTLL--------------------------------------
--------------

PF03144 // ENSGT00910000144046_0_Domain_0 (435, 518)

-E-----TGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVCVKDVHRGN

ENSGT00910000144046_0_Linker_0_1 (518, 533)

VAGDSKND-P-PV--

PF03143 // ENSGT00910000144046_0_Domain_1 (533, 709)

-E-AAGFT
AQVIILNHP---GQISAGYAAVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMAPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVTKAVDKKA-----VT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ALFA-YTL-------SVN--------KMDSTKPPYS--QK
R----YEEIIKK-ISTYIKRT-GYNP--NTVAFLPISGWNCDHMLE-PS-----ANM-PW
-HKGW-KVT-HKDGHARGTTVL-----------EALYC---ILSPAQLIDKPLCLPLQ-D
VHT----IGGV-ATLPVGWVETGLLKPD--I-VVTFAPV---ISQVKSVEMYHEAL----
----SE--ALPGDSVDFK-GK-----NMYVKD--RGSTAGDSKND-S-SI---D-AAGS

PF03143 // ENSGT00910000144046_0_Domain_1 (540, 626)

T
AQVIKLNHP---VEISAGQAPIGN--------------------CHTDHIACKF-GELKN
S---------------------VDATIISEVPGKPMHVK-----SFFDSPPLGR-VAVCN
MRQL-----------------------------------------LKAVVKKAAGAGKVT
KSAQKEKKLK--------------------------------------------------
----------------------------------------

------------------------------------------MGKE

PF00009 // ENSGT00910000144046_0_Domain_0 (47, 404)

KTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYI----
--------------STYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDSTEPPYS--QK
R----YEEIVKE-V----------------IAFVPISGWNGDNMLE-PS-----ANM-PW
-FKGW-KVT-RKDGSASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 518)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGSN-VK-----NVSVKDVRRGN

ENSGT00910000144046_0_Linker_0_1 (518, 535)

VAGDSKND-P-PM---E

PF03143 // ENSGT00910000144046_0_Domain_1 (535, 709)

-AAGFI
AQVIILSHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMVPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VD---------------------------------V--GVIKAVDKKAAGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------

------------------------------------------MGKEKTHINIV-VIGHV-
DSGKST-T--TGHLIYKCG-GIDKR--TIEKFEKEA-AEMGKGSFKYAW---VL-----D
KL-KAERERGI--TI-DISLWK-----FETS--KYYVT--IIDAP-----GHRDFIKNMI
T----G-TSQAD-CAVLI-VAA-GVGEFEAGI---------SKNGQT-------------
-----------------REHALLA-YTLGVKQLIVGVN--------KMDSTEPPYS--QK
R----YEEIVKE-VSTYIKKI-GYNP--DTVAFVPISGWNGDNMLE-PS-----SNM-PW
-FKGW-KVT-RKDGNASGTTLL-----------EALDC---ILPPTRPTDKPLRLPLQ-D
VYK----IGGI-

PF03144 // ENSGT00910000144046_0_Domain_0 (433, 520)

GTVPVGRVETGVLKPG--M-VVTFAPVNV-TTEVKSVEMHHEAL----
----SE--ALPGDNVGFN-VK-----NVSVKDVRRGNVA

ENSGT00910000144046_0_Linker_0_1 (520, 529)

GDSKND-P-

PF03143 // ENSGT00910000144046_0_Domain_1 (529, 710)

PM---E-AAGFT
AQVIILNHP---GQISAGYAPVLD--------------------CHTAHIACKF-AELKE
KIDRRSGK-KLEDGPKFLKS--GDAAIVDMIPGKPMCVE-----SFSDYPPLGR-FAVRD
MRQT-VA---------------------------------V--GVIKAVDKKAGGAGKVT
KSAQKAQKAK--------------------------------------------------
----------------------------------------