Query Results 

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------------------------------------------------------------
-----------------------------------------------------------M
P--LFFIL-------AELAMLL--A---------------------AL-----DSEG--I
WLHITVPQKIEPFK-----GGD--S-------

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

EGK-VSYVITIDGKPYFLHLRN-Y----
------SFLSRNFSVYA--YNETGSLYSD---SPHF------------------------
----LAHCHYRGYVGEVPDS-IVTLSLCS---GL---R---GFLQLENTSYGIEPLE-SS
-ARFEHIV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YQMKSN-S-----STLAAN----Y-S----CIWQ-TSR-Q-L------DKGH
FR-------EQDKNDSQLLPK

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 756)

SLKLHIIVGKFLFDYMGS-DIMAVTQKIFQIIGLVNTMF
TQLNLNVVL------ASLELWSDKNQIS-TD-----GNASDILQRLLGWKRDYLT---PQ
SNEITHLLI----YRKH-----LK-YIGA------TS--PGELCNES-YVAGV-GT---Y
PEDIGLEGLSMVITQL-IGLHIGL-TYD-DV-----------DNCSCPR---APCIMQPE
ALSSSGMKTFSNCSVHDYTHYASK--LDM--QCLGD--LS-N--VL---QPKQ-----SV
CGNGIVEG--SEECDCGNE-T---EC-QF---KECCNHETCKLKG-SAQCGSG------T
CCT-PKCELSAAGTPCRKAVDPECDFTEYCDGSSSHCVPDTFALDGHLCRL-GS-AYC--
---YNGRC-QALND-------------QC--VSLFGK---GS---QGASY-----ACFEK
VNSQRENLANCDSKN-------------------SYSLPCGQKDVLCGKLACFRPNKN-Y
KSS--T---QSVLYSYV----H-GSVCLSI----------------PP-GLSMR------
--------SDGKDNAYVADGTVCGPQ---------MYCIN--G-SCKEVNF-TGN--DCN
AAKKCKG-NGIC-----NN--FGH-CQCFPDYR-PP----------DCNL----------
-QI-GSPGGSIDDGNLLR---TD-S-----------------------------------
--------------------ALAT-K---RLSQH-------ADSWVILGFFIFLPF----
--IMTL---------F-LGIIKRNER------KIVP----Q---KEQER-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--VLFLL-------SGLGGLW--M--------------------------DSNFDS--L
PVQITVPE

PF01562 // ENSGT00910000144019_0_Domain_1 (249, 429)

KIRSIIK----EE---I-------ESQ-VSYKIVIEGKPYTVNLMQ-K----
------NFLSHNFRVYS--YNGTGIMKPL---DQDF------------------------
----QNFCHYQGYIEGYPKS-VAMVSTCT---GLR------GLLQFENVSYGIEPLE-SS
-VGFEHVIYQVKHK-KA-D-VSLYNE----KD-I-------E-SRD-L-S------FKLQ
SI-------EPQ----KDFAKYIEMHVVVEKQLYNHMGS-GTTVVTQKIFQLIGLTNAIF
VSLNITVIL------SSLELWIDENKIA-TT-----GDAKELLHTFLRWKRSYLV---LR
PHDVAFLLV----YREK-----SN-YVGA------TF--QGKICDAN-YAGGV-LL---H
PRTISLESLAVILAQL-LSLSMGI-PYD-DI-----------NQCQCSA---AVCIMNPE
AIHFSGVKIFSNCSIEDFAHFISK--QKS--QCLHN--QP-R--LDPF-FK----QQ-AV
CGNAKLEA--GEECDCGTQ-Q---NC-FLLG-AKCCDTATCRFKA-GSNCAEG------P
CCE--NCLFMSQERVCRPSFD-ECDLPEYCNGTSASCPENHFIQT

PF08516 // ENSGT00910000144019_0_Domain_9 (886, 1072)

GHPCGP-NQ-WVC--
---IDGVC-MSGDK-------------QC--MDTFGG---EA---EFGPT-----ECYSY
LNSKSDVSGNCGIGDS------------------G-YTQCEADSLQCGKLICKYAGEFLL
QIP--R---ATIIYANV----S-GHLCVAV----------------EF-ASDH-------
---------EDSHKMWIKDGTSCGSN---------KVCKN--Q-RCVSSSY-LGY--DCT
TD-KCNH-RGVC-----NN--KKH-CHCSASYL-PP----------DCSV----------
-QSDTSPGGSIDSGNFPL---VAV--P---------------------------------
------------------ARLPER-R----HMENV-YH----SKPMRWPLFLFIPF----
--FIIF---------C-VLIAIMVKVHFQ---RKKW----R---TEDYSSDDG-------
-SLKAKSSR-------PAWATQ--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--VLFLL-------SWLGGLR--M--------------------------DRNFGN--L
PVQITVPEK

PF01562 // ENSGT00910000144019_0_Domain_1 (250, 429)

IRSITK----EG---I-------ESQ-VSYKIVIEGKPYTVNLMQ-K----
------NFLPYNFRVYS--YNHTGIMKPL---DQDL------------------------
----QNFCHYQGYIEGYPKS-VVMVSTCT---GLR------GLLQFENVSYGIEPLE-SS
-VGFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQVKHK-KA-D-VSLYTE----KD-I-------E-SRD-L-P------YKIQ
SI-------EPQ----PDFP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYVEMHVVVEKQLYNHMGS-DTTVVTQKIFQLIGLTNAIF
VSFNLTIIL------SSLELWIDENKIA-TT-----GDANELLHTFLKWKRSYLV---LR
PHDVAFLLV----YREK-----SN-YIGA------TL--QGKMCDVN-YAGGV-VL---H
PRTISLESLAVILAQL-LSLSMGI-TYD-DI-----------HKCHCSG---AVCIMNPE
AIHFSGVKIFSNCSIEDFAHFISK--EKS--QCLHN--QP-R--LDPV-FK----QQ-PV
CGNAILEA--GEDCDCGSE-E---NC-TLIR-ATCCDGATCRLKA-GFNCAEG------P
CCE--NCLFLSKERVCRPAFD-ECDLPEYCNGSSASCPENYYVQTGHPCGT-NR-WIC--
---IDGVC-VTGDK-------------QC--RDVFGQ---EV---EFGPA-----ECYSY
LNSKTDISGSCGKVDS------------------R-YTQCEAENLQCGKLICKYVGAFLL
QIP--R---ATTIYANI----S-GHLCVAV----------------EF-PSDH-------
---------ADSQ-XWIKDGTSCGSN---------KVCRN--Q-RCVSSSY-LGY--DCT
EQ-KCSN-KGVC-----NN--RKH-CHCGPSYL-PP----------NCTT----------
-QSDLWPGGSIDSGNFPP---APANLP---------------------------------
------------------Q------R---RFIENI-YH----SKPMRWPLFLFIPF----
--FIIF---------C-VLIAIMVKVYFQ---RKKW----R---AEDYSSDEQ-------
-LESESEPK-------G-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAVCGA-L---MHTRITL
L--LLCL-----------EVSL--------S-IH------GL----

PF01562 // ENSGT00910000144019_0_Domain_1 (227, 429)

-S-Q-ARPS-QHFS
SPEVVIPSKVTSRGR-----GA--------KAPGW-LSYRLRIGGQRHIVHMRV-K----
----R-LLVSTHLPVFT--YTEQHGLQED---HPFV------------------------
----PDDCYYHGYVEGAPES-LVALSTCSG--GF----R--GMLQINDLMYEIEPIR-HS
-TTFEHLMYQVGSD-ET--ESPHMRCGLTEES-I-----ARQ-WAF-Q-AS-----YNFS
LK-------PRSHLNWWAHWRFVELGVVVDYFRFEYSQS-NETIVMLEIFDIINMVDEYY
YHIQIDVVL------TGIEIWNNGNPIE-TS-----GEIDPVLNRFSLWKSLNFDG-RLH
-HDVAHLII----KEF------NG-ALGV------AY--VSGVCRHR-INCGVDVF----
QDHRL-DIIAHTLTHE-LGHSLGM-LH--DE-----------KWCTC--GE-QFCIMHPS
REA---SRRFSNCSYSQYLA---NTMVTG--TCILS--PG-N--PEHV---LR----MNI
CGNRVVED--GEQCDCGSF-L---EC-IE---DPCCLF-DCVLKP-GAACAFG------G
CCK--DCELLPQGTVCRHPAN-ECDLPEWCNGTSHECPDDVYKQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGILCST---NSYC--
---YENAC-NNHDS-------------QC--KQIFGT---EA---LSASE-----SCYNE
MNTQGTRFGHCGIE-------------------GTTYVKCMAPDVMCGRVQCENVLTIPT
LIE--HS---TVHQFHL----N-GTTCWGT----------------DY-HLGMS------
-------V---PDIGEVKDGTVCAPG---------KMCLR---RKCVDMVK-ASE--TCQ
T-QHCNM-SGVC-----NN--KQH-CHCHPGWA-PP----------NCTI----------
-RG---PGGSVDSGPAPP---LPPEENPPVPGS---------------------------
---------------------------------------TQNKIMLLPSTLLLIPL----
-ILSCLYC---------FLVL----------CKKE-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLVVL-------SGLKGLQ--A---------------------DQ-----D

PF01562 // ENSGT00910000144019_0_Domain_1 (235, 429)

SQK--T
FLQTTVPEKISSPDV----EKD--P-------ENH-VAYLITLAGKPYFVHLKK-Q----
------SFLSPTAAVYS--YDKNGTQQSQ---SLSA------------------------
----LTSCNYNGYVAGFPNS-LVAFSICS---GL---RL--GTIQFKSISYGIEPME-AV
-WGFAHMIYKSANS-KI-S-IPVFAEN----D-T-----YWF-NQ--S-Q------HEFR
NS-------VNRSEFTKLSPRCIEMDIVVDKSLFDYMGS-DIKAVTQKVIQIIGLVNTML
SKLKLTVLI------SSIEIWSNKNKIS-TT-----GDLDRVLYRFLDWKHSNLD---HE
PHHISYLLS----FEER-----PS-SIGA------TY--PGMLCSEN-SNGAV-IL---Y
PKGLSLESYSVIVVQL-LGLGLGL-TYD-DA-----------DACFCSG---DVCTMTPE
AVYSEGTKDFSSCSLDDFKYFTSH--NDL--QCLRD--IP-V--ERRR-PPPKPPR--WT
CGNGVVEG--KEQCDCGTL-K---NC-TH---KNCCDPMSCRLKH-KAICGSG------E
CCG-QDCTLEPIDTPCRKTVD-ECDFPEYCNGNLSYCVADTYAR

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1067)

DGQPCDS-GG-AFC--
---YQGLC-RTFDK-------------QC--TALLGK---PS---TGASF-----GCFEE
MNSRGDRFGNCGRI------------------------SCIFQNSLCGKLVCSWPYKRLL
WRA--N---LSVVYAHV----R-DEICIST----------------YK-GGRIP--KN--
-TPTTYLSKEDRDETFVEDGSICGPE---------MYCLN--M-ECKETRF-LIDYKSCD
SSITCSG-NGIC-----NN--FQH-CHCNKGFF-PP----------FCEK----------
-KE-G-EFGSIDDGHLYH---IPGR----S------------------------------
------------N---LQK----------KHGIS-------GKHWYQLIFYISLPV----
--TVVI---------I-AAIIKQSKL------IELC----S---KEEPESYRY-------
-IHYRCIYD-------YYYYIKLISLRIK-----HW------V---RQHNKRHRDTFQIG
FIAM--VHFITESPS--AYL----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAVDGT-LVY---IRVAL
L--LLWL-----------GVFL--------S-IS------GY-----C-Q-AGPS-QHFT
SPEVVIP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

LKVISRGR-----SA--------KAPGW-LSYSLRLGGKRHVVHMRV-K----
----K-LLVSRHLPVFT--YTDEHALLED---QPFI------------------------
----PDDCYYHGYVEGVPES-LAVFSACFG--GF----R--GVLQINGLTYEIEPIR-HS
-ATFEHLVYKINSN-ET--QFSAMRCGLTEKE-V-----ARQQLGF-E-EA-----DNSA
LE-------PKSAGDWWTHAWFLELVVVVNHDFFIYSQS-NISKVQEDVFLVVNIVDSMY
KQLGSYVIL------TGIEIWNQGNVFP-MT------SIEQVLNDFSQWKQISLS--QLQ
-HDAAHMFI----KNSL-----IS-ILGL------AY--IAGICRPP-IDCGVDNF----
QGDTW-SLFANTVAHE-LGHILGM-QH--DE-----------EFCFC--GE-RGCIMNTF
RVP---AEKFTNCSYADFMK---TTLNQG--SCLHN--PP-R--LGEI---FM----LKR
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ER--EEQCDCGSI-Q---QC-EQ---DACCLL-NCTLRP-GAACAFG------L
CCK--DCKFMPSGELCRQEVN-ECDLPEWCNGTSHQCPEDRYVQDGFPCSD---SAYC--
---YQKRC-NNHDQ-------------HC--REIFGK---DA---KSASQ-----NCYKE
INSQGNRFGHCGIN-------------------GTTYLKCHISDVFCGRVQCENVRDIPL
LQD--HF---TLQHTRI----N-GVTCWGI----------------DY-HLRMN------
-------I---PDIGDVKDGTVCGPG---------KICIH---KKCVSLSV-LSH--VCL
PE-TCNM-KGIC-----NN--QHH-CHCGYGWS-PP----------YCLH----------
-RG---YGGSVDSGPASA---KKRGFLP--------------------------------
-------------------------------------------------L--IVIP----
-SLSVLIF---------LFTVGLL------MYLQQ---C-SG-PKETK--AHSSG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MLSLTWGM-RLVER-P---VVPRVLL
L--LFAL-----------WLLL-LVPVWCSQGHP------TW-----R-Y---------I
SSEVVIPRKEIYHTK-----GL--------

PF01562 // ENSGT00910000144019_0_Domain_1 (271, 427)

QAQRL-LSYSLRFRGQRHIIHLRR-K----
----T-LIWPRHLLLTT--QDDQGALQME---YPFF------------------------
----PVDCYYIGYLEGILQS-MVTVDTCYG--GL----S--GVIKLDNLTYEIKPLN-DS
-QSFEHLVSQIVSE-SD-DTGPMNAWKHWSHN-T------GS-PSS---R-L--EYADGA
PR--------LSSKNYATHPAAIKGHFQATHSVYSASGGDKLSSTVEYLFKVISLMDTYL
TNLHMRYYV------FLMTVYTEADPFS--Q------DFRVPGGQAHTFYERVFYA-HFR
-PDAGAIIN----KNSP-----GDDAVNP------A---ERSICSPS--ALICLGQ----
HGRNP-LFLSIIITNR-VGRSLGL-KH--DE-----------GYCICQRR--NTCIMFKN
PQL---TDAFSNCSLAEISNILNT-PDLM--PCLFY--DR-H--VYYN-----TSLTYKF
CGNFKVDN--NEQCDCGSQ-K---AC-YS---DPCCGN-DCRLTP-GSICDKE------L
CCA--NCTYSPSGTLCRPIQN-ICDLPEYCSGSKFICPDDTYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCSE---EGYC--
---YKGNC-TDRNI-------------QC--MEIFGV---SA---KNANI-----KCY-D
INKQRFRFGHCTRAEE-----------------SLTFNACADQDKLCGRLQCTNVTNLPF
LQE--H---VSFHQSVI----S-GVTCFGL----------------DE-HRG--------
--------TETADAGLVRHGTPCSRG---------KFCDR---GACNGSLSRLGY--DCT
PE-KCNF-RGVC-----NN--RRN-CHCHFGWS-PP----------KCKE----------
-EG---HSGSIDSGSPPV---QRRIIKQNL------------------------------
---------------------------------------------EPV-VYLRILF----
-GRIYFLFVA----LL-FGIATRVGVTK------I-----FR-FEDLQAALRSWQ-----
EQAKDK------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MVTVREA-L---VHARITL
L--QVWW-----------RVLL--------F-SS------VW-----P-M-TLCT-EHKA
PPETVIPVRVIVSSK-----EM--------SL

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

TGW-MSYSLHFGGHRHIISLKS-K----
----N-FLVSRQLPVFT--YSDQGVLFED---RPFV------------------------
----QTDCYYLGFVDEDPES-MAALTTCFG--GF----Q--GILQINDTTYKIKPKT-PS
-FTFEHLLYKIDSE-ET--QLHPMRCGLTDEE-I-----AGQ-VRL-Q-EN-----DKST
LM-------QSIYGSWWSHGLYIKLALVIDHEQFLYRKS-NTSLVLKDVFNIMNGINLSL
LSVDINVAL------LGLTIWTQRNPIP-V------QDIYTLLPAFCLWKTMNFNS-QMA
-YDIAHLFV----NYTF-----GD-YFGI------AF--VGTVCNKT-FGCGVDRL----
FGDNF-LTIGHIVAHE-IGHNLGM-PH--DG-----------ILCSC--GE-GPCLMSAT
MES---SKKLSNCSYEFLWA----NIAKK--SCLQR--EP-S--SSDI---FP----MKI
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

DD--GEECDCGSQ-S---CG-RN---SRCCLP-TCILKS-GAKCASG------L
CCN-FKCQIQPSGTLCRTKEN-ECDLPEWCNGTSKECPEDTFVQAGTSCLG---NGYC--
---YEKRC-NSHDD-------------HC--KRVFGE---HA---MKASD-----RCYKE
LNTRGDRFGNCGLK-------------------NKGYVRCETSDILCGRIQCAKVKTFPI
LES--HY---TVHWTRF----N-DASCWST----------------DY-HLGMK------
-------I---ADLGDIKDGTNCGPQ---------HVCIS---RKCVNKPS-WKS--DCS
PE-TCNM-RGIC-----NN--KQH-CHCDFGWS-PP----------LCVD----------
-NG---TGGSIDSGSPAP---EDPN-----------------------------------
----------------------------------A--NK---RKGIGKFIILLLPI----
-IFV---V---------VVLFL-------LFYLFRT-NRLSL-GGD----KQ------AK
K-----------------------------------------GEEAKPPEEEA-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
R--LWLLL-------AGLCCLL--AS--------------------RP-----GFQN--S
PLQIIIPEKIQTNTN--D

PF01562 // ENSGT00910000144019_0_Domain_1 (259, 429)

SSEI--E-------YEE-ISYIIPIDEKPYTVHLKQ-R----
------YFLADNFMVYL--YKQ-GSMNAH---SSDI------------------------
----QAQCYYQGNIEGYPES-MVTVSTCS---GL---R---GILQFENVSYGIEPLE-SA
-VEFQHVL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YELKNE-DN-D-FAIFSEN----S-R----SLEE-H-P-M-D------DNIF
IS-----EKSEPV-VPDLFPL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

YLEMHIVVDKALYDYLGS-DSMIVTNKVVEIIGLANSMF
TQFKVTIVL------SSLELWSEENKIS-TV-----GEADELLQRFLEWKQSYLN---LR
PHDIAYLLI----YRDY-----PD-YVGA------TF--PGKMCVTH-YSAGV-AF---Y
PREITLETFSVIVTQM-LALNLGI-SYD-DP-----------KKCQCSE---SICIMNPE
AMQSNGVKTFSNCSLRNFQNFISN--MGA--KCLQN--KP-Q--MQA-----Q--R--PV
CGNGRLEG--NEACDCGTE-A---QC-GP---ASCCDFRNCVLKA-GATCYKG------L
CCR--DCQILQSGVECRPKAHPECDIPENCNGSSPECGPDITIINGHLCKK-NK-FIC--
---YDGDC-HDLDA-------------RC--ESVFGK---GS---KNAPF-----ACYEE
IQSQSDRFGNCGRDRY------------------NRYVLCGWRNLICGRLVCTYPTRTPF
RQE--N---GDVIYAFV----R-DSVCVTV----------------DY-KLPR-------
---------SVPDPLAVKSGSPCDIG---------RVCVN--R-QCVESRI-IKASAHAC
SE-QCSG-HGVC-----NS--KNI-CHCSPGYQ-LP----------NCQT----------
-RS---KGFSVFPEED-----MD-------------------------------------
--------------------SIME-R--ASE--K-------AENTWLLGFSIALPM----
--LIVT---------TVIV-LARKQL------KKWF----TK--EEEFSSSES-------
-KSDGSTQT-------YASQSNSEGSTQT-----YA------S---QTRSESTSQADTSK
S---------ESEDSAQAY--------------------------TSRSKSQENT-----
-------QTQSS------------------------SN----------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------

PF01562 // ENSGT00910000144019_0_Domain_1 (375, 428)

EGAPDS-LATFSTCFG--GL----W--GMLQLQGRLYQVEPLP-AS
-ATFEHR

ENSGT00910000144019_0_Linker_1_5 (428, 501)

VSRLV-E-R---PPGNLTCGLTDEE-I-----AHQ-AAQ-F-RPP--ASF---
-R-------QVDWHDAYIHP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYVELAVAVDNGRYKFRKN-NISAVIQDTILLISLVDSYF
APFKAHISL------KALEIWNDTDKVK-VI----NRTVRQILTDWTAYQSKEIYP-RVQ
-QDFAHLYV----FSI------AD-TTGT------AN--LYSMCKKT-KMASLSML----
PGNNL-VGPSKWTAHK-LGHSCGI-VH--DG-----------AYCWCGR---SLCIMNAF
G-R--FEGGFSNCSFDSYFVYTQK--R-T--SCLLN--FP-G--LGF---V------VER
CGNKVVES--GEQCDCGSA-R---EC-KE---DPCCLP-NCTLRP-GMQCLSG------P
CCR--RCQFLPAKEVCRPKKS-ECDLEEFCNGTSNLCPSDMYIQDGTPCSS--N-AVC--
---YRGTC-HSHLE-------------RC--RSIFGK---EA---KEAPL-----PCYDE
VNYHGDRFGNCGYE-Q-----------------EY-YLFCEGDSTLCGRVQCVNVQTIPS
MPE--HT---TVIQTHL--KDR-NITCWGT----------------EY-HLAMG------
-------TLGLSDIGDVQDGTLCGSD---------LICIN---RTCHELSL-LNF--NCK
P-EKCNH-RGVC-----NN--QKH-CHCDFGWA-PP----------FCET----------
-PG---DGGSIDSGPAGK---PLA------------------------------------
-------------------------------------------DEHLEQ-----------
---------G----L--IGA--SSGGSKW-E---------EI-CQVGLKG----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWS-KDLPVKGASGG
L--SCWAT---------------LSSQDG------------------A-C---------T
SSEMC-TRRSPKQW----------------------------------KSKAEM-R----
----S-NEITCALIIFTM-N

PF01562 // ENSGT00910000144019_0_Domain_1 (321, 428)

ADDQTMQED---YPFV------------------------
----PRDCYYDCYLEGVPGS-VATLDTCHG--GL----R--GMLQVDDLTYEIKPLE-AS
-SKFEHVVSLLVSE-ER--PGEASRCKTEGE-------ERDQESEK--------VKLAET
PR-------AGHVYLWRHHRKNLKIHYTVTNGLFQRN-P-NMSHIIENVVIINSIIHTIF
KPVYLNVYI------RVLCIWNQRDFVK---F-YQ-TSAGTAVENFGLWKLFRWYT-KIE
-HDTSVVFT----AYQL-----ENKDCYA------Q---FNGMCNPN-WGAMFVYL----
MRYHL-FRGACLTAHA-LGHNLGL-TH--DS-----------AGCYCFRR--TNCLMAPV
PDL---NDMMSNCSYERIQLR-LN--GWD--PCLSE--PN-I--PYTN-FPYV----ADR
CGDKIKNQ--REECDCGSL-K---DC-AN---DRCCET-SCILSL-GSVCNTG------L
CCR--ECKYAAPGVVCRDLGG-ICDLPEYCDGKNEECPNDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCSA---VSVC--
---VRGNC-SDRDM-------------QC--QALFGY---QV---KDGSP-----ACYQQ
LNRIGDRFGNCGVILRRG---------------GSKPFPCEEDDVFCGMLHCSGVSEIPG
GGE--HTTFRSILVRDI----K-EEKCFGY----------------EA-HHG--------
--------TDLPEMGLVVDGATCGPG---------SYCLK---HNCTFYQD-LHF--ECD
LK-TCNY-KGVC-----NN--QKH-CHCVFGWQ-PP----------TCEL----------
-RG---TGGSIDSGPPPD---KQYHIAGSI------------------------------
-------------------------------------------LVNTNR-ALLLIF----
-TRYILLLVS----LL-FGGFS------Q----AIE---FML-EKVLQTTEPE-E-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSVQI-L---LSQCRLL
L--VLVPT-VLL--LNSLGEDV-------IF-HP------QG-----E-F---------D
SFEITIPEKLSFRGE-----VQ--------GV

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

VSS-VSYQLQLKGKKHVLHLWP-K----
----R-FLLPRHLRIFS--FTEHGELLED---HPYI------------------------
----PKDCNYMGSVEESLDS-KATISTCMG--GL----R--GVFNIDGKHYQIEPLK-AS
-PSFEHVVYLLK-K-E---QFGNQVCGLSDDE-I-----EWQ-MAP-Y-ENK--A-----
-R-------LRDYPGSYKHPKYMELILLFDHSRYSFVNN-NLSQVIHDGIILTAIMDTYF
QDVRMRIHL------KALEVWTDFNKIR-VG----YPALADVLGRFVIYKKSILNA-RLS
-SDWAHLYL----QRKY-----ND-ALAW------SF---GKVCSLE-YAGSVSTL----
LDANI-LAPATWSAHE-LGHAVGM-LH--DE-----------QYCQCRGR--LNCIMGSG
------RSGFSNCSYISFFKHIS--SG-A--TCLNN--IP-G--LRY---V------LKR
CGNKIV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ED--NEECDCGST-E---EC-QK---DRCCQS-NCKLQP-GANCSTG------L
CCH--GCRFRPSGYMCRQEEN-ECDLAEYCDGNSSSCPNDVYKQDGTPCKY--K-GRC--
---FRKGC-RSRYM-------------QC--QSIFGP---DA---MEAPS-----ECYDA
VNLIGDQFGNCEIT-G-----------------IRNFKKCESANSICGRLQCINVETIPD
LPE--HT---TIISTHL--GAE-NLMCWGT----------------GY-HLSMK------
-------PMGIPDLGMINDGTSCGED---------RVCFN---KNCVNSSV-LQF--DCL
P-EKCNT-RGVC-----NN--RKN-CHCMYGWA-PP----------FCEE----------
-VG---YGGSIDSGPPGL---FGG------------------------------------
--------------------------------------E----IPQSIR-IVSIIM----
-FQAKTRTG---------------------------------------------------
--------------------------------T----SKANVE-SKRPKAKSVKKEKK--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--ILLLL-------SGLSGLG--RL--------------------SEPQTKG--SE--L
HV

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 429)

QVTVPEKIRSIQS----EG---Y-------ESQ-VAYNITIEGKTYTLNLTQ-K----
------MFLPPSFRVYS--YDNTGIMRPL---DQNF------------------------
----QNICYFQGYIEGYPDS-MVIVSTCT---GLR------GFLQFGNISYGIEPLE-SS
-IGFEHVIYQVEPK-KG-D-ALLYAA----KD-M-------E-LRD-L-K------YNIQ
SI-------KAE----KAASRYLEIHFVVEKEMYNHIGA-DTAIVTQKIFQLIGLANAIF
APFNLTVIL------SSLEFWMDENKIS-TT-----GDANELLYRFLKWKQSYLA---LR
PHDMAFLLV----YRET-----SD-YVGA------TF--QGKMCDKN-YAGTV-AL---Q
PKAVTLESLAIVLVQL-LSLSMGI-AYD-NV-----------SECHCGV---SICVMNPE
AIHSSGVRAFSNCSMEAFSSFISS--QNS--YCLQN--QL-Q--LQPS-YK-----S-KV
CGNGQL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EE--GEDCDCGS--R-------CES-PSCCDPATCQLTK-GSLCAEG------P
CCA--NCQVKAKGEVCRISSG-DCDVTEYCNGSSAVCEEDFYVHDGHPCGG--E-WVC--
---VKGSC-KDGKQ-------------QC--RDLFGY---DA---DFGTD-----ECFDE
LNSKTDITGNCGINPS------------------G-YMACSPNNRKCGKLICKYRSENLI
KMK--S---ATVIYANI----S-GEICISL----------------EY-VRGH-------
---------KDSQNMWVDDGTVCDTN---------KVCMN--K-ECVEDTI-FNY--DCK
PE-NCNN-HGVC-----NN--KKN-CHCNPTYL-PP----------DCKT----------
-TQDQWPGGSINSGNQQR---AE-------------------------------------
-------------------SILA--R---PQIESA-YH----AKPSRWPFFLIIPF----
--YIVI---------C-VLIAILVKVHSQ---RKKW----R---TDDYSSDEQ-------
-FETETETK-------D-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------SER--L
NVQVTVPEKIQS

PF01562 // ENSGT00910000144019_0_Domain_1 (253, 429)

IEG----EGH--A-------ATH-ISYSIMIEGKTYTMHLKQ-K----
------PFLPRSFKVYS--YDGSGIMMPL---DEDI------------------------
----ESSCHYQGYLEGYPNS-MATLSTCT---GLR------GILQFGNISYGIEPLE-SA
-LGFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQLQHK-KT-S-ISLYAE----KE-F-------E-LRD-L-P------YEVQ
RI-------EAQ----KDLP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

HYIEMHIVVEKRLYDHMGS-DTTIVTEKIFQLIVLTNAIF
ASINLNIIL------SSLEFWTDENKIS-TS-----GNANELLHKFLKWKRSFLV---LR
PHDMAFLLI----YKEA-----SN-YIGA------TI--QGKMCDKN-FAGGV-VL---H
PRIISLESLAIILVQL-LSFSMGI-SYD-DL-----------SKCHCPG---AVCIMNPE
AIHASGTKTFSNCSLEDYALFLAS--PMS--HCLQN--QP-H--LQPS-YK----TD-AV
CGNGIVEK--GEACDCGSK-M---EC-EAKP-FQCCNSQTCTLAS-DMECDTG------P
CAG---------------------------------------------------------
----------------------------------------------FGSD-----QCFEE
MNSRTDISGNCGIEDS------------------V-YQACAPNNRKCGKIVCRYRGSEVL
KLR--D---AITVYINA----S-GQVCVSL----------------EF-PVNH-------
---------NEWQKMWVNNGTICNAQ---------KVCRN--K-ECVENSY-LNY--DCT
PQ-NCNN-RGVC-----NN--KKN-CHCEAKYL-PP----------NCAN----------
-TNEDWPGGSINSGNHPM---ES-------------------------------------
-------------------PISG--R---QYFESV-YH----PKPPRWPFFLIIPF----
--FIIL---------C-ILIVMLVKLYFQ---RKNW----K---TDDYLSDEQ-------
-IGSESETR-------E-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------I

PF01562 // ENSGT00910000144019_0_Domain_1 (281, 429)

IPINQKPHMVHLKQ-K----
------YFLADHFVVYL--YKQ-GSVTSH---SSDI------------------------
----PAQCYYHGYIEGYPSS-VATLSTCS---GL----R--GMLQFENVSYGIEPLE-SA
-VEFQHILYKLGNE-NN-V-LESFNER----G-K----TMEE-N-Q-V-D------YSIF
IN-----VPP----PPNLLPLYLEMIIVVDKGLYDYLGS-DRVIVTNKVIEMVSLINSMF
TQFNVTVVL------SSLELWSDKNKIS-TN-----GEADELLKRFLEWQQSYLA---LR
PHDVSYLLI----YKDH-----PN-YVGA------TF--PGKMCVSH-YSVGI-AQ---Y
SRDMTLEAFSVTVTQM-LGINLGI-SYD-DP-----------QKCHCSE---AVCVMSPK
AVQSSVLKTFSNCSQRDFQAFISN--MGS--KCLQN--KP-Q--LQA----KK--T--AV
CGNGKV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EG--DEICDCGTA-E---QC-GS---SSCCTPGMCVLKP-TSQCDGANPN--HR
CCD--SCKFAAESTECRPVRHPDCDLPEKCNGSSGFCPPDIHVLNGNMCKG-DK-YFC--
---HDGIC-HDLDQ-------------RC--ENVFGT---GS---TNGPF-----SCYEE
IQSQTDRFGNCGKDLR------------------GRFTYCGWRNLICGRLICAYGSRKPF
IPT--NN-ATAVVYAYV----R-DTICITA----------------DF-SATS-------
---------NEGDPLLLRSGPICDDG---------RICVN--F-VCVEARA-LKTQAETC
A-QKCNG-NGVNCFVCTNS--EDL-CKCKEGFN-PP----------DCKS----------
-PS---KRSSVWTGKG------G-------------------------------------
--------------------VTVE----GIS-PK-------AEKKWLLGLYIGLPA----
--LVMA---------TLVV-VAWNNW------KKWF----A--KKEECQSS---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MP--R----------PPLLP
P--LQLLL-------AGLW-AL--AS--------------------EP-----GSQN--S
FLQIIFPEKMKG

PF01562 // ENSGT00910000144019_0_Domain_1 (253, 429)

NTS---------S-------EEQ-ISYIIPIDEKPYTVHLQK-R----
------YFLADHFMVYL--YNQ-GSINYH---ASAS------------------------
----PAQCYYQGYVEGYPNS-VVTLSTCS---GL----R--GILQFENVSYGIEPLE-SA
-IIFQHIV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKLGNE-DN-A-LANLNKN----S-R----SIAD-P-P-L-D------YGIL
ID-----GRSEQP-LPVLYPL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

FIEMSIVVDKDLCDYLGS-DSRILTNKIIEIISLVNSMF
SQLKVTIVL------SSLELWSDENKIS-TA-----GEPDDLLRRFLEWRKGFLT---LR
PHDIAYLFK----YNEN-----LE-YMGA------TF--PGKMCVTS-HSAGI-AV---Y
LKGMTLETFAVIVTQM-LGLSLGI-SHD-DP-----------VKCHCPA---AVCVMNPK
TMQTSGRKIFSNCSLNDFQNFILN--VGA--KCLQN--KP-Q--FQV----SP--R--PF
CGNGIVEG--KEACDCGNK-N---QC-GP---DSCCDPQSCVLKP-GKECDSQSPT--ST
CCE--ACKFLAKGQECRPAKHRECDIPEFCNGSTARCPPDITIQDGNMCKK-NS-FFC--
---YDGDC-HDLDA-------------RC--EHHFGK---GS---KKAPF-----SCYEE
IQSQTDRFGNCGKDSH------------------NRFIFCGWRNLICGKLICTYPRRTPY
ISK--FK-SSSVIYAFV----R-NKTCVSV----------------DV-GS---------
---------ITDDPFMVKSGPICDID---------RICIN--S-VCVESRH-IKAISAEC
S-KKCSG-HGVC-----DS--LGT-CRCEAGYE-PL----------T-------------
------------------------------------------------------------
----------------------MQ-R--A-S-RK-------AEKKWLPGLYIALSV----
--LIAA---------TLVV-VAWSSL------KSWL----P--QEEGSLRSKS-------
-KSQGSHES-------HSS-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------

PF01421 // ENSGT00910000144019_0_Domain_5 (517, 806)

MGS-DINAVTQKVIQIIGLVNTML
TQLELTVMI------SSIEIWSNKNKIF-TT-----GHAEDVLLQFFEWKKDHLN---FK
PHQIACLLV----YRKL-----PT-LIGA------TF--PGQVCNKD-FAAAV-AL----
------------------------------------------------------------
------------------------------------------------------------
------------------------NC-TH---KLCCDPSTCRMKG-NAKCGSG------D
CCS-KDCKFKPANTIYRKSVDKECDFTDYYNGDLPYCLPDTYVRDGEYCDS-DG-AFC--
---FQGKC-WTFDK-------------QC--DDLIGR---GS---RGAPI-----FCYDE
INTRGDNFGNCGTA------------------------HCLFQHILCAKLFCTWEHRDLI
SRP--N---LSVIYAHV----G-DQTCVSI----------------YL-PRRTPPPVNSP
ISITSYYSAEDRDETFVQDGSMCGPD---------MYCFE--M-HCKHVRF-LMNLKLCD
ASNHCDR-HGVC-----NN--FNH-CHCEKGYN-PP----------YCQP----------
-KQ-G-AFGSIDDGHLVP---PTV------------------------------------
------------------FKDS----------------------NFRGIFSCYDTV----
--AWN-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPSRA-QNL-LTGALCL
S--VFSAV---------------LSPVCCSHDPP------TW-----H-F---------T
SSEVVIPRKVPHKMD----

PF01562 // ENSGT00910000144019_0_Domain_1 (260, 428)

-GS--------KTPEQ-LSYTMRFRGQRHVIHMKL-K----
----K-NLLPKDFMVAT--NNDQGAIQED---YPFV------------------------
----PRNCYYSSYLEGVPGS-TATLDTCSG--GL----R--GMLQLDDFTYEIKPLA-AS
-SKFEHIVSLLVAQ-YV--SEKDKKCDIPED-------EADQLLEE--------VKLVES
SR-------SAPVYLWRIHRKQIHVHYTISNSLWAQD-Q-NQSRVVEKIVIINNINHSIF
RPMGLNVFV------RMVCIWSGGDQV---------------------------------
-----TILT----GHSI-----GTFNYYA------N---RDGMCNPN-WGVLYLFM----
SRYHI-FMSAAILAHA-MGHSINM-HH--DS-----------EGCVCFRR--SHCLMSPT
PGF---FDTASNCSFTEVHRR-IH--SWD--VCLSR--MF-V--PYNN-FPYV----APR
CGDKIVNN--NEDCDCGTL-K---AC-AS---SKCCTT-DCVFTA-GSVCNSG------E
CCV--KCEYALPGVICRDTLG-ICDLPEYCSGKNESCPHDFYIQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCSP---QAVC--
---MHGNC-SDRDL-------------QC--QALFGY---EV---KDAPK-----LCYEK
LNIIGDRFGNCGLREQRP---------------GVIPSKCDADNVLCGILHCSSPGIVPG
GGE--HTTFHDIIIQDV----K-QEHCFGY----------------DV-HLG--------
--------TEIPEMGLVVDGATCGPG---------RFCRK---QNCTFHDD-MGF--DCD
VK-SCNF-RGVC-----NN--LKH-CHCARGYN-PP----------NCSG----------
-RG---LGGSVDSGPPPT---REEGIRARI------------------------------
-------------------------------------------IFAVNE-TLLLII----
-VRFGLLLAA----MV-IAKRA------V----EKK---VYQ-EEYEESESES-S-----
----D-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------KVAMSEA-L---VQVRISL
L--QIWW-----------KVLF--------F-PS------VW-----P-L-SWCA-EFKS
LPEVVIPLRVAVSSR-----DM--------SL

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

AGW-KSYRLHFGGQRHIISVKP-K----
----N-FLVSRHLSVFT--YNDQGVLFED---RPFV------------------------
----QNDCYYLGFVEGDPES-MVALTTCFG--GL----Q--GTLQINDTAYEIKPKS-AS
-STFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 503)

YKIDND-KA--QLPSMRCGLPDEE-R-----AGQ-VRL-Q-KD-----DDSS
VT-------QIVYGDWWTHRLN

PF01421 // ENSGT00910000144019_0_Domain_5 (503, 760)

IELALVIDHKQFLYRKS-NASLVIQDVFMIMSGLNFFL
FPADINVDL------LGLEIWNNKNPIP-V------KDIYTLLPTFCKWKRENLDS-YIP
-HDIAHLLV----NYNF-----SN-YFGI------AY--VGTICNKT-FGCGVESL----
LGENF-FTFGHIVAHE-IGHNLGM-PH--DG-----------IFCTC--GT-EPCVMSAT
MEG---SRKFSNCSYAVLWE----NTAKT--SCMYN--KP-N--SSAI---FP----FKF
CGNRVVDQ--GEECDCGSP-E---EC-KY---SLCCLP-DCSLKA-EADCATG------L
CCS-NLCQILPSGTLCRIPEN-ECDLPEWCNGTSHECPEDVFMQDGSSCTN---GGYC--
---YEKRC-NSHDE-------------HC--RRVFGK---DA---RKASD-----SCYQE
LNTYGDRFGNCGIM-------------------DNVYVKCNSSDILCGRVQCNEVKKLPF
WRS--HY---TAHWTHF----N-GVSCWSI----------------DY-HFGMT------
-------I---PDLGDIKDGTSCGPE---------HVCIN---RKCVSKSL-WRS--DCS
PE-TCNK-NGVC-----NN--KHH-CHCDPGWS-PP----------HCLV----------
-NG---TGGSIDSGSPGN---ETDEREDDKD-----------------------------
---------------------------------MD--KE---EITGKNLISWLFPI----
-SFA---V---------FLSLL-------FLWLFSG-TPP--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

IIIFLYTHN--------L-------------------------------TL-P----
----Y-NFFQTL---FH--LNYTLSLTSP---SWPA------------------------
----HNDCYYHGYVEGDPES-LVALSTCLG--GL----Q--GILQTNDLVYEIEPKR-RS
-TTSEHLIYKVDSE-ET--QLPPMRCGVTDEE-I-----AQQ-LKF-P-ES-----VNFT
LM-------QSGYEGWWTHRRILELAVVVDHYRYLHHQS-NTTAVQYEVLLVANKVNNFL
SSLDVDVVL------MGIEVWTEKNPIK-ID------NIVDLLEEFCIWKQTSFNS-RLP
-HDVAHLFV----KHSY-----GI-TLGI------AF--IGTVCNFT-YNCGVESL----
MYNNL-YMVAYTMIHE-IGHNFGM-LH--DG-----------PTCTC--GH-KTCVMFPG
ISG---TTRFSNCSYASFIN---TT-ASQ--NCMYI--SS-N--TGNI---FT----LAR
CGNNVIEE--GEECDCGAL-H---LC-IN---DPCCES-NCILKP-GAACASG------L
CCK--DCQILPTGEVCRQEEN-DCDLPEWCNGTSYHCPEDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

NGVPCKG---GGYC--
---YEKRC-NNREE-------------QC--RNIFGK---EA---KSANQ-----SCYTE
MNTRGDRFGNCGLM-------------------NASYVKCNNSDTLCGRVQCENVTELPL
LRD--HS---TVHWTQF----N-DITCWGT----------------DY-HFGMT------
-------I---PDIGDVRDGTECGEE---------RVCIQ---RKCVHRSL-LVN--NCS
LK-TCNL-KGVC-----NN--RQH-CHCNYKWD-PP----------FCLK----------
-RG---HGGSIDSGPPP-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
R--LWLLL-------ARLCGLL--AS--------------------RP-----GFQN--S
LLQIVIPEKIETNTS--D

PF01562 // ENSGT00910000144019_0_Domain_1 (259, 429)

SSEI--E-------YEQ-ISYIIPIDEKPYTVHLKQ-R----
------YFLADNFMIYL--YDQ-GSMNAH---SSDI------------------------
----QTQCYYQGNIEGYPDS-MVTLSMCS---GL---R---GILQFENASYAIEPLE-SA
-VEFQHVL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKLENE-DN-D-IAIFSEN----N-R----SLEE-H-P-M-D------DNIF
IS-----EQSEPA-VPDLFPL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

YLEMHIVVDKALYDYWGS-DSMIVTNKVIEIVGLANSMF
TQFKVTIVL------SSLEVWSHENKIS-TV-----GEADELLQRFLEWKQSYLN---LR
PHDIAYLLI----YRDY-----PD-YVGA------TF--PGKMCITR-YSAGV-AL---Y
PKEITLEAFSVIVTQM-LALSLGI-SYD-DP-----------KKCRCSE---SICIMNPE
ALQSNGVKTFSSCSLRSFQNFISN--VGA--KCLQN--KP-Q--MQK---KSP--K--PV
CGNGRLEG--SEICDCGTE-A---QC-GP---ASCCDFRTCVLKD-GAKCYRG------S
CCR--DCQILQSGVECRPKAHPECDIAENCNGSSPECGPDITLFNGLPCKN-SK-FIC--
---YDGDC-HDLDA-------------RC--ESVFGK---GS---RNAPF-----ACYEE
IQSQADRFGNCGRDRN------------------NKYVFCGWRNLICGRLVCTYPTRKPF
HQE--N---GDVIYAFV----R-DSVCVTV----------------DY-KLPR-------
---------TVPDPLTVKNGSQCDVG---------RICIN--R-ECVESRK-IKALALVC
SEHLCSG-HGVC-----DS--RKN-CICSPGYN-PP----------SCQT----------
-RS---KGFSIFPKED-----MD-------------------------------------
--------------------SIME-R--ASG--R-------TENTWLLGFSIVLPI----
--LIVT---------TIVV-LARKQL------KKWF----I--KEEEFPSSE--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------LQPRQR-TSSL----DVLWDTVAMSEA-G---AHTSISH
Q--HLWL-----------EMLI--------I-LS------TW-----P-L-NGHA-QHTS
LPEVVIPLRVTSN-R-----TM--------WAM

PF01562 // ENSGT00910000144019_0_Domain_1 (274, 417)

GW-LTYSLHFGGQRHVIYMKA-N----
----K-FFMSRHLSVFT--YTDQGSLHKE---QPFV------------------------
----QKDCYYHGYMDGDPES-MVVLTTCFG--GI----Q--GTLQVNGTVYEIKPK

ENSGT00910000144019_0_Linker_1_5 (417, 501)

N-LS
-STFEHLVHKIDNE-ET--KLLPMRCALTEEE-I-----ALQ-MKL-Q-ET-----DNHT
LM-------QSSYEGWWAHK

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 754)

RFLNLVLVVDHERIRYLNS-NLSHVLREILIIVHAIHEIF
LTLDVEVVL------FGVEMWNAGNQVK-VT------TIDHLLRDFCYWKWISLNN-RIQ
-NDIAHLFV----KHDF-----GS-KNGL------AD--VGSVCVQS-KNCGVDRL----
EGSEL-HHFGQLTAHG-IGHNLGL-KH--DE-----------HTCKC--GY-YACIMAQA
GIG---VNKFSNCSYAAFWS---TY-AGA--NCLRK--EK-K--PVMK---FK----FKS
CGNGVVED--GEQCDCGSW-Q---AC-RA---DPCCVE-GCMLQG-GASCAFG------L
CCK--DCKIMPSGTMCREPAN-ECDLPEWCDGHSHECPNDVYLLDGSSCKD---GGYC--
---YEKRC-NSRDE-------------QC--QQIFGK---EA---RSAAQ-----SCYRE
INTQGDRFGNCGIF-------------------RSTYLRCKDSDILCGRVQCENVKVIPT
LEG--HS---TVHWIHL----N-GVTCWGT----------------DY-HFGMT------
-------I---PDIGHVKDGTDCGPE---------HVCID---RKCVNKSV-WVS--DCS
PK-TCNS-NGVC-----NN--LHH-CHCNLGWD-PP----------ECFT----------
-NG---SGGSIDSGPPSP---DSP------------------------------------
--------------------------------------------NYYMNSLIL--L----
-A--IFPC---------F--VY--------ACFHN----RY-------------------
--VTSS-R-----EEEPAVSTSE----------------A--------EEESSDVS----
----------SASKI-----------S---------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--ILLLL-------SGLSGLG--GL--------------------SEPQTKDARER--L
HVQITVPE

PF01562 // ENSGT00910000144019_0_Domain_1 (249, 429)

KIRSILS----GG---Y-------ESQ-VAYNLTIEGKPYTLNLRQ-K----
------AFLPPNFKVYR--YDNAGIMRPL---DQHF------------------------
----QNACYFQGYIEGYPDS-MVIVSTCT---GLR------GFLQLGNVSYGIEPLE-SS
-IGFEHVIYQVEPK-KR-D-ALLYAE----KD-I-------E-LRD-L-K------YKIQ
SV-------TPR----QVVPYYAEIHIVVEKEMYEHIGA-DSAIVTQKIFQLIGLANAIF
APFNLTVIL------SSLEFWMDENKIL-TT-----GDANELLYRFLNWKQSYLV---LR
PHDMAFLLV----YRET-----SD-YVGA------TF--QGKMCNKN-YAGGV-AL---H
PRAVTLESLAIVLVQL-LSLSMGI-TYD-NA-----------SNCHCGV---SICVMNPE
AIHSSGVRTFSNCSTENFFNFISS--PNS--YCLRN--KP-Q--LQPS-YK-----A-AV
CGNGEL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EE--DEVCDCGP--Q---GC-GDQT-PPCCDPNTCKLPD-GSVCADG------P
CCK--DCNMKPKGEVCRPPRG-ECDLAEYCNGTSPMCAEDFFIIDGHPCGQ-DK-WVC--
---LNGSC-QDGEQ-------------QC--RDVFGY---EA---DFGTN-----ECYDE
LNSKTDISGNCGISPS------------------G-YKACSPNDRKCGKLICKYESENLI
KIR--A---ATIIYANI----S-GHICISL----------------EY-AANH-------
---------KDSNNMWVRDGTVCAAN---------KVCMN--K-ECVE--V-LNY--DCS
PA-DCNN-HGVC-----NN--KKH-CHCTASYL-PP----------DCVN----------
-MQDEWPGGSVDSGNQQR---AE-------------------------------------
-------------------SIPA--R---HYVATA-YR----SKPTRWPFFLIIPF----
--YIVI---------C-ILIAILVKVYSQ---RKKW----R---TSDSSSDEQ-------
-FETETETK-------D-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------M

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

F
L--LLALL-------AELGGLH--A---------------------HL-----DAER--L
FLYVTVPQKIRSNE-----SED--S-------EKQ-VTYIITIDKKPYTLHLRK-X----
------XXXXXXXXXXX--XXXXXXXXXX---XXXX------------------------
----XXXX---XXXXXXXXX-XXXXXXXX---XXXXXX---GFLQFENITYGIEPLE-SS
-ARFEHIIYEVKND-NP-D-MPMLAEN----Y-S----NIWQ-KD--Q-P------YKIH
LS-------SQXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXX------XXXXXXXXXXXXX-XX-----XXXXXXXXXXXXXXXXXXX---XX
XXXXX

PF01421 // ENSGT00910000144019_0_Domain_5 (606, 760)

XXXX----YRKQ-----PK-YVGA------TV--PGTICNES-YDADI-AM---Y
PDAMTLEGFSVIITQL-LGLKIGL-TYD-DI-----------NKCSCPR---ATCIMNHE
AVVSSGIKIFSNCSMHDYRYSVSK--FET--QCLQS--FS-K--LKPL-YQNQ-----SV
CGNGILEP--HEECDCGSE-E---EC-QF---KNCCDYNTCKLKG-SVKCGSG------S
CCT-SKCELSVAGTPCRKSIDQECDFTEYCNGTSSNCVPDTYAMNGQLCRL-GT-AYC--
---YNGQC-QTTDN-------------QC--AKLFGK---GV---QGAPF-----ACFEE
VNSLHNRLGNCGFQN-------------------SQPLPYEQKDVLCGKLACVWPQKNPF
KTD--V---RSAVYLYT----Q-GHVCIT--------------------TGSMR------
--------SGGRDYAYVADGTVCGAQ---------MYCVN--K-TCKEVPL-MGY--N

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CD
ATEKCKG-NGIC-----NN--LGN-CHCLPGYR-PP----------YCEL----------
-QI-DSPGGSIDDGNVYT---SD-I-----------------------------------
--------------------TLVK-K---GYKTH-------QSNWLTLSFYIVLPF----
--LICF---------T-TMIIKRNEM------RKVC----N---RENAEYE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MRCGLTEKE-V-----ARQQLGF-E-EA-----ENSA
LE-------PKSAGDWWTHAWFLELVVVVNHDFFIYSQS-NISKVQEDVFLVVNIVDSMY
KQLGSYVIL------TGIEIWNQGNIFP-MT------SIEQVLNDFSQWKLISLY--QLQ
-HDAAHMFI----KNSL-----IS-ILGL------AY--IAGICHPP-IDCVVDNF----
QGDTW-SLFANTVAHE-LRHSLGM-QH--DE-----------EFCFC--GE-RGCIMCTF
RVP---AEKFTNCSYGDFMK---TTLNQG--SCLHN--PS-R--LREI---FM----LKR
CGNGVVER--EEQCDCGSI-Q---QC-EQ---DACCLL-NCTL-P-GAACAFG------L
CCK--DCKFMPSGELCRQEVN-ECDLPERCNGISYQCPEDRYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1094)

DRIPCSD---SAYC--
---YQKRC-NNHDQ-------------HC--REVFGK---DA---KSASQ-----NCYKE
INSQGNRFGHCGIN-------------------GTTYLKCHISDVFCGRVQCENVRDIPL
LQD--HF---TLQHTRI----N-GVTCWGT----------------DY-HLRMN------
-------I---PDIGDVKDGTVCGPG---------KICIH---KKCQQIKL-HPS--LPL
VL-FVFL-V-----------------LRDDLWKRHE----------MCLH----------
-QS---VQG---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------VTVGEV-L---VHERIMV
F--QLCL-----------WMVL--------F-LS------PW-----S-L-TEHT-KYSS
PP

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 429)

EVVIPLRVTDTRR-----HD--------SSPGW-LSYSLRFGGERHIITMKP-T----
----K-YFISRNFLLLT--YTDKDDLLAE---QPFV------------------------
----QSDCYYHGDVDGDPES-MVSLTTCLG--SL----Q--GILEINGAVYEIMPKS-ST
-STFEHLL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQMKSE-ET--ESRPMRCGLTEEE-I-----AQQ-MKL-Q-DN-----HNDT
LM-------QSHYEGWWTHH

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 756)

KYIEYFVVLDNKRFVYTGS-NVTRSSNEVLAVFNGMKGYY
VSIEIDLIF------AGLEIWTEQNYVK-VE-----GNVISVLVSFCQWKERTNKA-RNQ
-YDIIHLWA----KEGY-----GT-NLGI------SY--IGSVCISD-SNCAINSF----
LWDTL-GPVSFSIAHE-LGHNLGM-PH--DQ-----------KNCVC--GQ-EKCIMFKE
MTM---STAFSNCSYAAMWD----RISQR--TCLRN--IA-N--DALT----P----PAS
CGNTLVEE--GEQCDCGSL-E---SC-KD---DPCCSQ-HCVVKP-GAECATG------P
CCK--NCKFMKPGTLCRGMND-ECDLPEWCNGTSAECPEDVFREDASPCNG----GFC--
---YKKAC-NTHNK-------------HC--QKIFGM---GA---RSTNE-----TCYMD
MNKRGDRFGNCGNN-------------------SYNYKKCSDSDILCGRIQCEDVTELPR
LQN--HV---TVYWTHL----N-TAICWTT----------------EY-HFGIN------
-------T---ADIGAVRDGTPCGPK---------HICIN---RRCVDMPI-LLS--NCS
EI-LCNM-QGVC-----NN--KHH-CHCNDEWK-PP----------DCVL----------
-SG---FGGSIDSGPPPV---RLSKK----------------------------------
-------------------------------------QL---I-------RYILGV----
-SV---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLVLL-------TGLGGMH--A---------------------DL-----NPHK--I
F

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 428)

LQTTIPEKISSSDA----KTD--P-------EHN-VVYMITIEGKPYFIHLKK-Q----
------SILSSASFIHS--YDKNDIRHSK---PLLV------------------------
----QMDCNYNGYVAGIPNS-LVTLSVCS---GL---R---GTMQLKNISYGIEPME-AV
-SGFIHNIYEEKFA-DT-N-I-LLEEN----D-T----YSWF--N--S-E------YQVR
KS-------SEKTDFIKLFPRYIEMHIVVDKNLFDYMGS-DINAVTQKVIQIIGLVNTML
TQLQLTVII------SSIEIWSNKNKIS-TT-----GHAEYVLLEFFEWKKDHLN---FK
PHQIAYLFV----YRKL-----PT-LIGA------TF--PGQVCNKD-FAAAV-AL---Y
PEGLSLESYTVIIVQL-LGLNLGL-TYD-KT-----------DTCHCSG---DVCTMTPK
AVYSGGVKDFSVCSLDDFKYISSH--NGL--TCLQT--NP-L--EMPT-YTQ---R--RI
CGNGLL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 877)

EG--GEECDCGNK-D---NC-TH---KLCCDALTCRLKD-NAQCGSG------D
CCS-KDCKFKPANTICRKSVDEECDFTEFCNGSYPYCLLDTYVRDGEYCDS-GG-AFC--
---FQGRC-RTFDK-------------QC--EDLIGR---GS---RGAPI-----FCYDE
INTRGDKFGNCGTE------------------------YCLFQHILCGKLVCTWEHRDLI
SRP--N---LSVIYAHV----R-DQICVST----------------YL-PSRKPPPVAST
VSSTSYYSVDDRDETFVQDGSVCGPD---------MYCFK--M-RCKHVRF-LMDFETCE
ASIECSG-HGIC-----NN--FNH-CHCEKGYN-PP----------HCKP----------
-KK-E-AFGSIDDGHLVP----AE------------------------------------
------------------KSYMEE-G---RHAPF-------QKQRFQLIFYISLPV----
--LIIT---------T-AILIKRKKL------RELC----Y---RGETESESS-------
-VSQESSSN-------SKSSLSER------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------M-A-ALT--VRR---
-R-------ARAWTSSYVHQKYMEVMVVLDKLRYNFLSS-NLTRAISDTLVMTGIMDSYF
QVLNARIQL------KAIEVWTDVSKVN-TS----VKKLIEVLEQFSEYRRKVLYR-EVR
-TDWTHLYV----HKFY-----PD-ALGW------AY--VGSVCDQS-YGASVSTL----
PDKNL-VAPSTWSSHE-LGHGVGM-AH--DN-----------KGCFCQGR--SQCIMGAG
G-----RFGFSNCSFVDYFNLVSV--K-G--DCLDD--IP-G--HQY---S------VKR
CGNKVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

DD--GEECDCGTM-E---EC-KK---DLCCRP-DCRLRP-GADCHTG------L
CCR--DCRFKPPGHVCRGKHN-ACDLAEFCNGTSPLCPDDFYKQDGTPCGK--E-ARC--
---YRKGC-NDRFL-------------QC--KRMFGS---SA---RDAPF-----ICYEE
VHRRSDRFGNCGLV-G-----------------RS-YKRCRENDMLCGRLQCVNVKSVPE
MPD--HT---TVVFTHL--KEF-NIRCWGT----------------DY-HSSMR------
-------AMELRDDGAVKDGTACGRN---------LICIN---RTCHDVSV-LKY--DCR
P-EKCNK-RGVC-----NN--RKD-CHCHYGWA-PP----------FCET----------
-PG---YGGSIDSGPAGK---MKT------------------------------------
-------------------------------------------VSKTVK-VVPIMF----
-IRLILLVTS----L--VGV--ILKEMIA-KFLKQR------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MVYM--YNQ-

PF01562 // ENSGT00910000144019_0_Domain_1 (324, 429)

GSVSAY---SSDI------------------------
----QPQCYYQGYIEGHPNS-VATLTTCS---GL----R--GMLQLENVSYGIEPLK-SA
-VDFQHILYKLGNG-IN-E-LGLFKKN----N-R----NIEK-Q-P-K-Y------YTIF
ID-----EKAD-LQAPDLFPLYLEMHIVIDKALYDYLGS-DSMIITNKVMEMISLVNSVF
TQFKVTVVL------SSLELWSDNNKIS-TV-----GGANELLQKFLDWKQSYLT---LR
PHDAAYLFI----YRDH-----PD-YMGI------TF--PGKMCVNL-YSAGV-VL---Y
SKDLTLEAFSVIVTQM-LGLSLGL-TYD-DP-----------IKCQCSE---AICIMTPE
AIQSTGAKTFSNCNLNEFRSFISY--VGA--RCLQN--KP-Q--MQR----NP--R--PV
CGNGIV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EG--NEICDCGNE-Q---QC-GP---QACCDHATCQLKE-QSECDKG------P
CCS--QCKFSQAGTLCRPMKHPECDMPEHCNGSSEHCVPDIFVKNGHQCKN-NA-FIC--
---YDGDC-HDLDA-------------RC--ESYFGN---GS---KNAPF-----ACYEE
VNAQVDSFGNCGMDRN------------------KRYILCGWRNLICARLICTYPFRTPY
IQP--S---ISVIYAYV----R-NHVCISL----------------FN-TSSP-------
---------TGHDPFVVKSGAQCDTG---------RVCVN--S-QCVESRP-MKSASSTC
T-QRCNG-HGVC-----NS--KDE-CNCTDGYL-PP----------DCQA----------
-QS---QRWAG--EE-------G-------------------------------------
--------------------LIIT-K--A-S-GK-------SRKNWLLSLYIGLPV----
--LLMV---------SIIA-VAWNSL------KKWF----T--KDKKSLGGEY-------
-KSEGSTKT-------YVSRSRAESS-S--------------------------QTDTTK
S---------IPEDST--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
-------------------------------------E------------QPGAISESLK
G-EQ----MEMLVPGVA--F-----VRCFTSILK--VVRWLQ--AP----------GTA-
L--LLRLW--V--

PF01562 // ENSGT00910000144019_0_Domain_1 (194, 429)

-WVVLGALLLPEVGGH-H-PP-------P-----G-Y---------A
VHEIVRPRKLVLTAG-----RS--------A-RGE-VSYVIRVEGENRIIRLTQ-T----
----R-GLVVNNLPLIT--YSPRGMRVVE---QPHV------------------------
----PEGCQHLGYVEGSPGS-MAALSTCA---GL----R--GQLRIGNLSYGIEPVP-GS
-LTFQHLLYRRE-S-----WDKSSTCGLTDIA-M-----RKQ-PSW-M-GAK--KPLG--
---------KQGLDQRLQHTRYVEIFVVVDHQLFSFQGS-NETSVMFLVIDTINLSEIHY
YPLKIRICL------IGLEIWTRGNFIR-YS-----PDIEEVLTNFNDWGNRHLSR-RIK
-YDVAHLFT----YTDF-----GL-TVGL------AY--VGSICYPG-YQSGLVSH----
IQEDF-VIFATIFTHE-LGHNLGM-EH--DR-----------KECRCGN---AKCYMTGG
SID--GATAFSNCSIQSYLDLLNR--GDG--NCLNN--IP-E--PNRL-FY------FKT
CGNKVIDE--GEQCDCGGL-Q---HC-QG---NPCCFH-SCRLKP-GAVCSVG------Q
CCQ--KCHFHPSGHKCRSEVD-ECDLPEYCNGTSEWCPEDLHMQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGTPCSD--N-GYC--
---YRGKC-TSHDK-------------LC--RKIFGD---EA---RGAPE-----SCFEE
QNMKGDRFGNCGG--DGN---------------EVAFVECKPQNALCGRLQCVNVKKTAF
LEK--FE---TIIQTPG----P-EDWCWGT----------------AH-HAS--------
--------IDTPDIGG

ENSGT00910000144019_0_Linker_9_10 (1097, 1139)

GTDGTKCGPK---------KICIN---KTCTDVI--VRT--K

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CD
AKVLCKG-NGVC-----NN--LEH-CHCKAGWA-PP----------DCQF----------
-RG---LGGSMDSGPPPA---LMI------------------------------------
----------------------------------S--IA----EAVQDKAFGTAIGIT-V
LVALVLVA------LL-IAAIKYINAII-----TLF-----S-TNSSTE--TPETPENEE
QNMEEEEDEEAEV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLALL-------TELGRLQ--A---------------------HE-----GSEG--I
FLHVTVP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

QKIKSND-----SEV--S-------ERK-MIYIITIDGQPYTLHLRK-Q----
------SFLPQNFLVYT--YNETGSLHSE---SPYF------------------------
----MMHCHYQGYAAEFPNS-FVTLSICS---GL---R---GFLQFENISYGIEPVE-SS
-ARFEHII

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQMKNN-DP-N-VSILAVN----Y-S----HIWQ-KD--Q-P------YKVP
LN-------SQIKNLSKLLP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 756)

QYLEIYIIVEKALYDYMGS-EMMAVTQKIVQVIGLVNTMF
TQFKLTVIL------SSLELWSNENQIS-TS-----GDADDILQRFLAWKRDYLI---LR
PHDIAYLLV----YRKH-----PK-YVGA------TF--PGTVCNKS-YDAGI-AM---Y
PDAIGLEGFSVIIAQL-LGINVGL-TYD-DI-----------TQCFCLR---ATCIMNHE
AVSASGRKIFSNCSMHDYRYFVSK--FET--KCLQK--LS-D--LQPL-HQNQ-----PV
CGNGILES--NEECDCGNK-N---DC-NP---CFF-LLSIC-------------------
----------LVDRPPSLYFEPMCVFAC--------------------------------
---------------------------EM--SLLNTA---RA---QGAPF-----ACFKE
VNSLHERSENCGFKN-------------------SQPLPCERKDVLCGKLACVQPHKNAN
KSE--V---QSTVYSYI----Q-DHVCVSI----------------AT-GSSMR------
--------SDGTDNAYVADGTMCGPE---------MYCVN--K-TCRKVHL-MGY--NCN
ATTKCKG-KGIC-----NN--FGN-CQCFPGHK-PP----------DCKF----------
-QF-GSPGGSIDDGNFQK---SG-D-----------------------------------
--------------------FYTE-K---GYNTH-------WNNWFILSFCIFLPF----
--FIVF---------T-TVIFKRNEI------RKS--------------LIRP-------
-LYQKAM-T-------W-------------------------D---INIAQN-FHSK---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------ADSER--L
RVQ

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

ITIPEKIRSTIS----GG---A-------ESH-VSYNIIIEGKTYTVNLMQ-K----
------AFLPHNFRVYG--YNGTGSMKPL---EQQF------------------------
----QNFCYYQGYIEGYPNS-MAIVSTCS---GLR------GLLQFENVSYGIEPLE-PS
-IGFEHVV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQVKHK-NK-G-VSLYAE----KD-I-------E-SRE-M-S------HKIQ
SI-------EPL----SEFS

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

QYIEMHVVVEKNLYNYMGS-DMIVVTQKIFQLIGLTNAIF
TSFNVTIIL------SSLELWIDENKIS-VT-----GDANELLHRFLKWKRSYLV---LR
PHDVAFLLV----YREK-----SN-YVGA------TF--QGKMCDSH-YGGGV-AL---H
PRTISLESLAVILAQL-LSLSMGI-AYD-DI-----------NKCQCSG---AVCIMNPE
AIHSSGVKIFSNCSMEDFAQFISK--PKS--QCLQN--QP-H--LDPS-YK-----V-AV
CGNGQVEQ--GEQCDCGSA-E---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------LEYGFIILDADA-G---ALMRVTL
L--LLCL-----------KVFL--------S-PI------DL-----S-Q-TGST-QYLS
SPE

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

VVIPLKVTSRAR-----GT--------KNSGW-LSYSLIFGGQRHVVHMRV-K----
----K-LLVPTHFSVLT--YTEEHTLLKD---YPFV------------------------
----PSDCYYHGFIEGAPES-LVALSTCSG--GF----Q--GVLQVNGFSYEIEPIR-QS
-STFEHLVYTLNNN-KT--QFPPMICGVTEKR-I-----PNQRFGL-E-EA-----ERSA
VK-------QNSG-KSWTHTWFLELAVVVDYGFFTYSQQ-NLSKVREDVVLIVNMVDSMY
KQLDTYVSL------IGIEIWNRGNVFP-VE------NIHQVLEDFSEWKQISLS--QVP
-HDAAHIFI----RSSL-----IS-VLGI------AY--VAGICHPP-LDCGVENF----
QGDSW-SLFANTVAHE-LGHTFGM-QH--DE-----------ESCTC--GE-RGCVMSEF
RVP---AERFTNCSYHDFVE---TTLNQG--TCLHN--HP-R--PGAV---FL----VKR
CGNGVVEK--EEECDCGSI-H---DC-EQ---DPCCLL-NCKLRP-GAACAFG------L
CCK--DCKLMLSGELCRPKVN-ECDLPEWCNGTSHQCPEDGYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1094)

NGVSCGV---SAYC--
---YQKQC-NNHDQ-------------QC--REIFGK---SA---RSASP-----NCYKE
MNSQGNRFGHCGTN-------------------GTIYLKCRMSDIFCGKVQCENVENILH
LQA--HS---VLQNIYA----D-GVACWST----------------DH-HLGMG------
-------V---PDVGEVKDGTTCGAG---------KICIH---KKCISLSV-LSN--ACL
PE-TCNR-RGIC-----NN--KHH-CHCDYGWS-LP----------FCLH----------
-RG---YGGSVDSGPTSP---KRRVNII--------------------------------
-------------------------------------------------ELSVILT----
-VLSILTC---------LLIAGLY------ILYH--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----T

PF01562 // ENSGT00910000144019_0_Domain_1 (367, 429)

QCYYQGNIEGYPES-MVTVSTCS---GL---R---GILQFENVSYGIEPLE-SA
-VEFQHVL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YELKKE-DN-D-FAIFSEN----S-R----SLEE-H-P-V-D------DNIF
IS-----EKSEPV-VPDLFPL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

YLEMHIVVDKALYDYLGS-DSMIVTNKVVEIIGLANSMF
TQFKVTIVL------SSLELWSEENKIS-TV-----GEADELLQRFLEWKQSYLN---LR
PHDIAYLLI----YRDY-----PD-YVGA------TF--PGKMCITR-YSAGV-AF---Y
PKEITLETFSVIVTQM-LALNLGI-SYD-DP-----------KKCQCSE---SICIMNPE
AMQSSGVKTFSSCSLRKFQNFISN--MGA--KCLQN--KP-Q--MQG-----V--R--SV
CGNGRLEG--SEVCDCGTE-A---QC-GP---TSCCDFRTCVLKA-GAKCYKG------L
CCR--DCQILQSGVECRPKAHPECDIPENCNGSSPECGPDITIINGHLCKK-NK-FIC--
---YNGDC-HDLDA-------------RC--ESVFGK---GS---KNAPF-----ACYEE
IQSQADRFGNCGRDRN------------------NRYVLCGWRNLICGRLVCTYPTRTPF
RQE--N---GDVIYAFV----R-DSVCVTV----------------DY-KLPR-------
---------SVPDPLAVKSGSPCDVG---------RVCVN--R-QCVESRI-IKDSAHAC
SQ-QCSG-HGVC-----NS--KNT-CHCSPGYQ-LP----------NCQT----------
-RS---KGFSVFPEED-----MD-------------------------------------
--------------------SIME-R--ASE--T-------TGNTWLLGFSIALPI----
--LIVT---------TVIV-LARKQL------KKWF----TK--EEEFSSSES-------
-KSEGSTQT-------YASQ----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

----------------------------------------------------------M-
S---AL------------------------------------------------HPKQL-
-TGRSQTSST-----------PHPAL--SSALDRWLHDDSSIMALGEA-L---VHITVTL
L--ILWV-----------GMSL--------F-IS------GH-----S-Q-AMPS-QHFS
-P

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 429)

ELVIPLKVTGRGR-----SA--------KSPGW-LSYSLKFGGQRHIVHMRV-K----
----K-FLLSKHFPVFT--YTDQHALLQD---QPFV------------------------
----PDDCYYHGYVEGISES-LVALSTCSG--GF----R--GMLQINDLAYEIEPIS-FS
-ATFEHLVYKIDSG-DT--QFPPMRCGLTEEE-I-----ARH-LQL-R-AS-----YNST
LM-------QNSYLGWWTHLRFVELVVVVDHFRYLYCKS-NVSLVQREVFDTVNIIGILY
SPLEVEIVL------NGIEIWSERNLIS-T------DTIEQILGDFSAWKFSNLDD-RLP
-HDTAHLFI----KKNF-----GI-KLGV------AY--VGGICHRL-FNSGVDVF----
EEDRL-YLFALTVTHE-LGHNMGM-TH--DT-----------KECKC--GL-PWCIMYDS
QSV---TARFSNCSYAEYWN---NILTKG--LCIHS--PP-Y--PGNV---FK----VQY
CGNLVI

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

EE--GEECDCGTT-D---QC-VN---DPCCLL-NCTLKP-GAACQFG------I
CCK--DCKLMPSGTLCRHQIS-ECDLPEWCNGTFHQCPEDVYVQDGIPCGD---NAYC--
---YEGRC-NNHDK-------------QC--REIFGK---DA---RSASQ-----SCYKE
INTQGNRFGHCGIT-------------------NLVYVKCEGPDILCGRVQCENVEMIPN
LIQ--HS---TVHQLHI----N-DTTCWGT----------------DF-HLGMS------
-------I---PDVGQVKDGTICGPE---------KICLH---KKCVNMTY-PPR--KCH
SNETCHM-HGVC-----NN--KQH-CHCKHGWA-PP----------YCKD----------
-AG---LGGSVDSGPPPK---EYVATLE--------------------------------
----------------------------------------AKALLGYLSLLWLIPF----
-TAFVLFC---------LLVV----------CMEKKR-EEEN------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------V-----------PHTLP--SSALDRWLHNYSSVMAVNEA-L---VHIRV

PF01562 // ENSGT00910000144019_0_Domain_1 (179, 429)

TL
L--LLWV-----------GMPL--------F-IS------GH-----S-Q-ARPS-QHFS
-PELVIPLKVTGRGR-----GI--------KGAGW-LSYSLQFGGKRHIVHMRV-K----
----K-LLVSRHFPVFT--YTDQHALRQD---QPFV------------------------
----PDDCYYHGYVEGIPES-LVALSTCSG--GF----R--GMLQINDLAYEIEPMR-FS
-ATFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YKIDSD-DT--QFPPMRCGLTEEE-I-----ARH-LQL-R-AS-----YNST
LM-------QSSYMGWWTHL

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

RFLELVVVVDHLRFLYYES-NVTVVQREVFDVVNIIDVLY
YPLEVDIIL------TGIEIWSERNLVA-T------DNMEQLVEDFAIWKFFNLDA-RLH
-HDTAHLFI----KKYF-----GI-KLGI------AF--VGGICQRP-FNSGVDVF----
EGDSL-YFFALTVSHE-LGHNLGM-SH--DT-----------EQCVC--GL-QWCIMYPS
QVA---TTRFSNCSYAQYWN---TSLTSG--VCIHS--PP-H--PGNI---FR----VQY
CGNLAVEE--GEECDCGTV-H---QC-VN---DPCCLL-NCTLKP-GATCTFG------I
CCK--DCKFMPSGTLCRHQIN-ECDLPEWCNGTFHQCPEDVYLQDGIPCGD---DAYC--
---YEGRC-NNHDK-------------QC--REIFGK---DA---RSASQ-----NCYKE
INTQGNRFGHCGIT-------------------DLIYVKCEAPDILCGRVQCENVRVIPN
LIQ--HS---TVHQLHF----N-DTTCWGT----------------DY-HLGMS------
-------I---PDIGQVKDGTVCGPQ---------KICIH---KKCVNKTY-PPR--D

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CQ
TDETCHM-HGVC-----NN--KEH-CHCSRGWE-PP----------YCEH----------
-PG---YGGSIDSGPPPG---KPVILVE--------------------------------
----------------------------------------PKAMLGHLSLLWLIPF----
-TAFVLFC---------LLV----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWL-QDP-LTGALWL
P--VLWAL---------------LSQVYCFHDPP------GW-----R-F---------T
SS

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 428)

EIVIPRKVPHRRR-----GV--------EMPDQ-LSYSMRFQGRRHVIHMKL-K----
----K-NMMPRHLPVF-T-DNDQGAMQEN---YPFV------------------------
----PQDCYYDCYLEGVPGS-VATLDTCHG--GL----R--GMLQVDDLTYEIKPLE-AS
-SKFEHVVSLLVSE-ER--LGEASRCKTEGE-------ERDQESEK--------VKLAET
PR-------AGHVYLWRHHRKNLKIHYTVTNGLFQRN-P-NVSHIIENVVIINSIIHTIF
KPVYLNVYV------RVLCIWNQKDLVS---F-YR-MPVGKAVRDFGVWKYHKWYS-NIK
-HDTSVVFT----AYRL-----ENRDCYA------N---FDGICNPN-WGAMFVYL----
MRYHL-FRGACLTAHA-LGHNMGL-TH--DS-----------AGCYCFRR--TNCLMAPV
PDL---NDMMSNCSYERIQHR-LN--MWD--PCLSD--PN-I--PYTN-FPYV----ADR
CGDKIKNQ--REECDCGSL-K---DC-AN---DRCCET-SCILSL-GSVCNTG------L
CCR--ECKYAAPGVVCRDLGG-ICDLPEYCDGKNEECPNDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCSA---VSVC--
---VRGNC-SDRDM-------------QC--QALFGY---QV---KDGSP-----ACYQQ
LNRIGDRFGNCGVILRRG---------------GSKPFPCEEDDVFCGMLHCSGVSKIPG
GGE--HTTFRSILVRDI----K-EEKCFGY----------------EA-HQG--------
--------TDLPEMGLVVDGATCGPG---------SYCLK---HNCTFYQD-LHF--ECD
LK-TCNY-KGVC-----NN--QKH-CHCVFGWQ-PP----------TCEL----------
-RG---TGGSIDSGPPPD---KQYRTASSI------------------------------
-------------------------------------------LVNTNR-ALLLIF----
-TRYILFLVS----LL-FGGFS------Q----ALH---FYG-REREGDNTME-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MGMGQ--CPP------LG-GAGA
V----ALI--L---ILCSGGEMLPTQLPSAE-PP-------P-----G-F-SG--ASRVI
YSEVMVPRQLELRHG-----

PF01562 // ENSGT00910000144019_0_Domain_1 (261, 429)

AA--------V-KDD-VAYLIVAEGSYYVIHLTR-A----
----K-NLVAKDLPVYT--YGARGELITE---FPYM------------------------
----QDDCFYEGFVEGSPGS-IVALSTCY---GI----R--GILQIGDLRYEVEPVP-NS
-TTFQHLI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YRTAPA-----EGSAPPCQLPMEH-P-----TK--DGD-HANGS--RKILII
EE-------VPGLESLPVST

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

RYLELALITNKELFKANRH-NETLMLHLFISISNILNTVY
KRMKLQVVL------SAVEMWTTKDHVV-AT-----QSLAQTLQSFSSWCQKDAAG-RLS
-YDHVELLL----GEHY-----KE--RGF------TW--KGMVCQP--KSIGIVSF----
SGQDA-VQNVMTLAHM-IGHSLGF-NH--DDRKQF---QHKPCDCNCTQ---RGCIMGS-
SPG--SCLAFSDCTLREYYKEVIR--KNK--PCLLN--IP-S--LKPS-L-------FEL
CGNGILER--GEECDCGND-K---EC-LK---EGCCLS-NCLLAP-GASCYRG------E
CCR--KCQFRPAGKICRAYQS-ACDLPEYCNGNSASCPVDVFKQDGTPCGS--N-DRC--
---YEGRC-HSHEA-------------QC--KALFGK---AA---HRAPL-----SCFRD
VNIRGDRCGNCGWN-------------------GTHYTKCLEGNILCGRVQCINIKRVPV
RQD--GE---TVVQTLL----N-NQLCWGL----------------EF-HLP--------
--------FDMHDDGSVKDGTSCGTN---------KICIN---RTCVSAAF-LNS--DCT
A-KQCHG-RGVC-----NN--KNN-CHCDVGWA-PP----------DCKA----------
-EG---FGGSVDSGPPPS---YYV------------------------------------
----------------------------------Y--GA----TVKA-------VG----
--TLLLFI------LI-SGIVLYKRAEIV-RYIHRW---RRQ-RLDKRNNPTPPL--PPP
PPGEESPGDA--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
C--LLLLL-------IGLIGLQ--T--------------------------DNNSER--L
RVQITIPEKIR

PF01562 // ENSGT00910000144019_0_Domain_1 (252, 429)

STLS----GG---I-------ESH-VSYNIVIEGKTYTVNLMQ-K----
------AFLPRNFRVYG--YNGTGSMKPL---EQQFQCKENIEMEESSARNDNDKTGKTE
EGNRTNFCYYRGFIEGYPNS-VVTISTCT---GLR------GLLQFENVSYGIEPLE-PS
-IGFEHVIYEVKHK-HK-G-VSLYAE----KG-I-------E-SRE-M-P------YKIQ
SI-------EPL----SEFSQYIEMHVVVEKNLYNHMGS-DTIVVTQKIFQLIGLTNAIF
TSFNITIIL------SSLELWIDENKIP-VT-----GDANELLHRFLKWKRSYLV---LR
PHDVAFLLV----YREK-----PN-YVGA------TF--QGKMCDNQ-YGGGV-AL---H
PRTISLESLAVIIAQL-LSLSMGI-AYD-DI-----------NKCQCSG---AVCIMNPE
AIHSSGVKIFSNCSMEDFATFISN--PKS--QCLQN--QP-H--LDPS-YK-----S-VV
CGNGQVEQ--GEQCDCGNA-E---DC-AANL-NSCCDHTTCTLTV-GSTCDIG------E
CCK--NCQYLAKGEICRPSSD-ECDLPEYCNGSSATCQDNFYIQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1071)

NGHPCGE-NQ-WLC--
---LNGSC-ISGIK-------------QC--VDLFGE---GA---DFGPE-----ECYAH
LNSKTDQSGNCGSGPS------------------G-YIQCKTKDLQCGKLICEYKKEEII
NIP--N---ATAIYANI----N-GHICVAL----------------DF-PHDF-------
---------IISKKMWVKEGTVCGNN---------KVCKN--K-ECVDAGY-LNY--DCT
PE-KCNE-RGVC-----NN--KKN-CHCNPSYL-PP----------NCET----------
-SDDAWTGGSVDSGNFPP---QVA------------------------------------
----------------AGLASSE--R---RYIENA-YH----SKPTRWPYFLLIPF----
--FIIL---------C-LLIAALVKVYFQ---RNKW----R---TEEYTSDEQ-------
-LESESEPR-------E-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-KLVED-Q---DTLKVAI
F--LLEL-----------WAH--LGSAQ

PF01562 // ENSGT00910000144019_0_Domain_1 (209, 428)

CSQDHP------SW-----R-Y---------I
SSEVVIPRKQMYHGK-----SF--------QVPGW-VSYSLKFGGQRHVIHMQL-K----
----K-LLRPRYLPVIS--QDDQSALQTD---HPYV------------------------
----PRDCYYIGYLEEIPYS-LVTVDTCYG--GI----E--GIMKLDDLTYEIKPLK-DS
-HRFEHI

ENSGT00910000144019_0_Linker_1_5 (428, 511)

ISQIVTD-EN-AREPAYKPGTQEE--I------DS-LFS---A----ENISIA
PR--------LSSTRFASHELSIEGLPQCS

PF01421 // ENSGT00910000144019_0_Domain_5 (511, 741)

HTMYRTIN--NFTECVKYMVSYTSVVGSFL
WALHFRYYI------TALIIYNERDPAS-LT------PYALPGSPFYTYYQQTIYE-NIQ
-HMSSFVVD----RDGP-----EDYAYNT------R---FQRVCNAD--SLVMVGQ----
LGRPY-ILLSTITAQN-IGLTLGL-PL--DG-----------EFCVCQRR--ATCIMQVY
PGI---TDAFSNCSFNHAGTVYIT--G-H--YCLAE--DR-Y--PLLN-----ETLTEFR
CGNEIVEE--AEQCDCGSF-K---KC-YS---NPCCNI-NCELTP-GSHCDIG------L
CCA--NCTYALTGMLCRPIKN-ICDLPEYCNGNTHTCPVDFYMQDGTPCSE---KSYC--
---YKGNC-TDRDL-------------QC--KAIFGN---VA---MDAPE-----ACY-T
LNTKGDRFGKCTRRTD-----------------SRYHTPCRPPDKFCGRLQCINVTHLPQ
LQE--H---VAFHQSLI----E-NNICFGL----------------DE-HRR--------
--------TGSIDVGRPIDGSICAPE---------TYCNF---VFCNGSVANISY--DCF
PE-KCNY-RGIC-----NN--LKN-CHCHVGWD-PP----------LCLK----------
-RG---AGGSINSGPPPR---KMRSVKQKT------------------------------
---------------------------------------------DVV-IYLRLVY----
-GRIYAFLFA----LL-FGLATNVRNIK------T-----TT-IIEEGTES---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
R--LWLLL-------ARLCGLL--AS--------------------RR-----GFQN--S
LLQIVIPEKIQTNTS--DG

PF01562 // ENSGT00910000144019_0_Domain_1 (260, 429)

SEI--E-------YEQ-ISYIIPIDEKPYTVHLKQ-R----
------YFLADNFMIYL--YDQ-GSMNAR---SSDI------------------------
----QTQCYYQGNIEGYPDS-MVTLSTCS---GL---R---GILQFENVSYAIEPLE-SA
-VEFQHVL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKLDNE-DN-D-IAIFSEN----N-R----SLEE-H-P-M-D------DNIS
IS-----EQSEPA-VPDLFPL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

YLEMHIVVDKALYDYWGS-DSMVVTNKVIEIVGLANSMF
AQFKVTIVL------SSLEVWSDENKIS-TV-----GEADELLKRFLEWKQSYLN---LR
PHDIAYLLI----YRDY-----PD-YVGA------TF--PGKMCITR-YSAGV-AL---Y
PKEITLEAFSVIVTQM-LALSLGI-SYD-DP-----------KKCRCSE---SICIMNPE
ALQSNGVKTFSSCSLRSFQNFISN--VGA--KCLQN--KP-Q--MQG---KSP--K--PV
CGNGRLEG--SEMCDCGTE-A---QC-GP---ASCCDFRTCVLKD-GAQCYRG------S
CCR--DCQILQSGVECRPKAHPECDIAENCNGSSPECGPDITLFNGLPCKN-SK-FIC--
---YDGDC-HDLDA-------------RC--ESVFGK---GS---RNAPF-----ACYEE
IQSQADRFGNCGRDRN------------------NKYVFCGWRNLICGRLVCTYPTRKPF
HQE--N---GDVIYAFV----R-DSVCVTV----------------DY-KLPR-------
---------TVPDPLTVKNGSQCDVG---------RICVN--R-QCVESRK-IKATALVC
SEYTCSG-HGVC-----DS--RQK-CVCSPGYN-PP----------SCQT----------
-RS---KGFPIFPKED-----MD-------------------------------------
--------------------SIME-R--ASG--K-------TENTWLLGFSIVLPI----
--LIVT---------TIVV-LARKHL------KKWF----I--KEEEFPSSES-------
-KSEGSTQT-------YASQSISEGSTQT-----YA------S---RTRSESSGQADTSK
S---------KSEDSTQAY--------------------------TSRSKSQEST-----
-------QTQSS------------------------SN----------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWV-QDP-LTGALWL
P--VLWAL---------------LSQVYCFHDPP------GW-----R-F---------T
SS

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 428)

EIVIPRKVPHRRR-----GV--------EMPDQ-LSYSMRFRGRRQVIHMKL-K----
----K-NMMPRHLPVF-T-DNDQGAMQEN---YPFV------------------------
----PRDCYYDCYLEGVPGS-VATLDTCHG--GL----R--GMLQVDDLTYEIKPLE-AS
-SKFEHV

ENSGT00910000144019_0_Linker_1_5 (428, 504)

VSLLVSE-ER--PGEASRCKTEGE-------ERDQESEK--------VKLSET
PR-------AGHVYLWRHHRKNL

PF01421 // ENSGT00910000144019_0_Domain_5 (504, 747)

KIHYTVTNGLFQRN-P-NVSHIIENVVIINGIIHTIF
KPVYLNVYV------RVLFIWNQKDAIK---F-YG-RPAQTAVELFGLWKYRKVYP-TIA
-HDTSVVFT----AYRL-----GNRDCYT------S---FDGICNPN-WGAMFVYL----
MRYHL-FKGACLTAHT-LGHNLGL-SH--DS-----------AGCYCFRR--TNCLMAPV
PDL---NDMMSNCSYERMQNR-LN--MWD--PCLSD--PN-A--PYTN-FPYV----APR
CGDKIKNQ--REECDCGSL-K---DC-AN---DRCCET-SCILSL-GSVCNTG------L
CCR--ECKYAAPGVLCRDLGG-ICDLPEYCDGKNEECPNDVYVQDGTPCSA---VSVC--
---VRGNC-SDRDT-------------QC--QALFGY---EV---KDGSP-----ACYQQ
LNRIGDRFGNCGVILRRG---------------GSKPFPCEEDDVFCGMLHCSGVSKIPG
GGE--HTTFRSILVHDI----K-EEKCFGY----------------EA-HQG--------
--------TDLPEMGLVVDGATCGPG---------SYCLK---HNCTFYQD-LHF--ECD
LK-TCNY-KGVC-----NN--KKH-CHCVLGWQ-PP----------TCEL----------
-RG---TGGSIDSGPPPD---KQYRVASSI------------------------------
-------------------------------------------LVNTNR-ALLLIF----
-TRYILFLVS----LL-FGGFS------Q----ALH---FYG-RERGRRQHNG-V-----
----NY-------IDTYWEI----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------SSIMVAGEA-E---VLMRV

PF01562 // ENSGT00910000144019_0_Domain_1 (179, 429)

VL
L--LFWV-----------GISL--------S-PS------GF-----S-Q-AEPS-RYLR
SPEVVTPMKVTGRGR-----SA--------KTSGW-LSYSLQFGNWRHVVHMRV-K----
----K-LLVSRHLPVFT--HTDQHVLLQD---QPFV------------------------
----PDDCYYHGYVEGIPES-LVALSTCSG--GF----R--GMLQINDLAYEIEPIS-YS
-TKFEHLVYEINTN-GT--QFPPMRCGLTKKE-I-----ALQQLKF-E-EV-----KKST
LK-------QNSNDKWWTHSWFLELVVVVDHNFLIYSQS-NFSMVQEDVFLVVNIVDSIY
QQLGTYVIL------IGIEIWNQGNIFP-MI------SIEQVLKDFSQWKQINLS--QLQ
-YDVAHFFI----KNSL-----IS-VLGI------AY--VAGICRPP-IDCGVNNF----
QGDSW-SLFALTVAHE-LGHTLGM-QH--DE-----------EFCLC--EQ-SGCIMNAI
RVP---AEKFTNCSYMDFTK---TTLNQG--SCLHN--IP-R--PGEV---FM----LKR
CGNGIV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

EG--EEECDCGSI-K---QC-EQ---DPCCLL-NCTLRP-GAVCAFG------L
CCK--DCKFVPSGELCRHQVN-KCDLPEWCNGTSHQCPEDGYVQDGIPCGD---NAYC--
---YQKRC-NSHDE-------------QC--REIFGE---GA---KSASQ-----SCYKE
INSLGNRFGHCGIN-------------------GTTYLKCNTSDIFCGRVQCENVRDIPH
LRD--HS---TLRQTHI----N-GVTCWSI----------------DY-HLGMD------
-------T---PDVGEVKDGTMCGPG---------KICIH---KKCVSLSL-LSQ--VCL
GE-TCNM-RGVC-----NN--KHH-CHCGYGWS-PP----------YCLH----------
-RG---YGGSVDSGPASV---K-KVFLL--------------------------------
-------------------------------------------------L--VVSL----
-ILSVLFL----------LSTAVF------MYLRK---P-FC-PKETK--AQSSG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWV-QDP-LTGALWL
P--VLWAL---------------LSQVYCFHDPP------GW-----R-F---------T
SSE

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 428)

IVIPRKVPHRRS-----GV--------EMPDQ-LSYSMRFQGRRHVIHMKL-K----
----K-NMMPRHLPVFT--DNDQGAMQEN---YPFV------------------------
----PQDCYYDCYLEGVPGS-VATLDTCRG--GL----R--GMLQVDDLTYEIKPLE-AS
-SKFEHVVSLLVSE-ER--PGEVSRCKTEGE-------EIDQESEK--------VKLAEI
PR-------AGHVYLWRHHRKNLKLHYTVTNGLFMQN-P-NVSHIIENVVIINSIIHTIF
KPVYLNVYV------RLLCIWNQKDAVK---F-SG-RQGHVAVELFGVWKYHNLYP-KIS
-HDTSVVFT----STRL-----KNSECYA------S---FDGICNPN-WGAMFVYL----
MNYHL-FRGACVTAHA-LGHNMGL-RH--DS-----------VGCYCFRR--TNCLMAPV
PDL---NDMMSNCSYEIIQHK-FN--QWD--PCLSA--PN-V--PYTN-FPYV----APR
CGDKIKNQ--REECDCGSL-K---DC-AS---DRCCET-SCTLSL-GSVCNTG------L
CCH--ECKYAAPGVVCRDLGG-ICDLPEYCDGKKEECPNDVYIQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCSA---VSVC--
---IRGNC-SDRDM-------------QC--QALFGY---QV---KDGSP-----ACYQK
LNRIGNRFGNCGVILRRG---------------GSRPFPCEEDDVFCGMLHCSGVSHIPG
GGE--HTTFRNILVHDI----K-EEKCFGY----------------EA-HQG--------
--------TDLPEMGLVVDGATCGPG---------SYCLK---HNCTFYQD-LHF--ECD
LK-TCNY-KGVC-----NN--KKH-CHCLHEWQ-PP----------TCEL----------
-RG---KGGSIDSGPPPD---KQYRIASSI------------------------------
-------------------------------------------LVNTNR-ALVLIC----
-IRYILFLVS----LL-FGGFL------Q----GRE---RER-AHTME------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------TTLMGPAWA-QTL-LRGALLL
H--IFWAL---------------LSSVCCSGDLP------AW-----R

PF01562 // ENSGT00910000144019_0_Domain_1 (229, 428)

-F---------A
SSEVVIPRKMPHRVG-----GA--------EMPGQ-LSYSMRFHGRRHIVRMKV-K----
----K-RLLPRHFPVIT--NNDQGAMHEE---YPFV------------------------
----PRDCYYYSFLEGVPGS-MATLDTCHG--GL----R--GMLQVDDFTYEIKPLE-SS
-SKFEHVVSHLVSE-GT--SGQGERCRNDGE-------DINHAFEE--------AKFVET
PR-------AAPISQWWPHRKYLKIHYHISNSLYNQN-R-NMTRIIENVVIINNIIHTIY
SHNHLDVHV------RVLFLWNNRDLVT---L-SHRGSSYNVMDDFGLWKWHRWYP-QIP
-HDTSLLLT----GHKI-----GGDTYFG------F---HDGTCNPN-WGASFVYI----
ERYHL-FLAATIAAHA-LGHSLSL-RH--DA-----------ESCYCFRR--SKCMMAPR
PGL---LDMMSNCSYQALHNK-VS--IWD--PCLSL--QN-V--PYHN-FPYV----APR
CGDKIVNQ-

PF00200 // ENSGT00910000144019_0_Domain_7 (790, 882)

-DEECDCGSL-K---EC-MV---DKCCGT-NCLLTL-GSACDIG------D
CCS--RCKYAPPGTICRKILG-ICDLPEYCDGKTHECPEDFYVQDGTPCSP---SAVC--
---IRGNC-SDRDM-------------QC--QSLFGY---QI---RDASP-----LCYKT
FNIIGDRFGNCGVRVIRG---------------GGKPVKCEEDDVLCGMLHCDNINHIPG
GGE--HSTFRHMIVPGM----K-QEKCFGY----------------DA-HFG--------
--------TETPYMAVVVDGATCGPG---------RYCLH---QNCTYYQD-LGF--DCN
VK-TCNF-RGVC-----NN--KKN-CHCQRGWK-PP----------NCTQ----------
-LG---VGGSVNSGSPPD---KERGIRASI------------------------------
-------------------------------------------VLRINK-VLFTVL----
-VRLSLFVGA----LF-VGSLC------Q-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------ML-RSVRT-A---FFQGRSL
L--VLVLT-MLL--VDSLDEDS-------FF-HP------

PF01562 // ENSGT00910000144019_0_Domain_1 (221, 429)

ER-----G-F---------D
SYEITIPRKLSFKVG-----EQ--------GTLKH-VSYLLQLKGKKHVVRLWP-K----
----R-FLLPRHLQVFS--FTEEDELLED---HPYV------------------------
----PRDCNFMGSVEGSQES-EATLSTCMG--GL----R--GILKIDTKLYQIEPLR-AS
-SDFEHVV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YLLK-K-E---QFSNHICDLNDDM-L-----DVP-MGL-Q-ENM--A-----
-R-------LRDFSDSYKHP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYMELGVIFDNDRYLFANS-NLTQALSDAIIMTAVIDTYF
QELSLRVHL------KALEVWTNGDKVD-VK----KSNLSEVLGLFVLYRRHTLNN-RMI
-ADWIHLYV----KRYY-----RD-ALGW------SY---GYMCTKL-YGASASVY----
PDLNI-LGPATWTTHD-LGHTLGM-KH--DV-----------KDCQCRGT--SACIMGFG
------RSGWSNCSYVDYYRQVT--FG-A--ACLNN--IP-G--VGY---V------IER
CGNKLVEG--DEECDCGSI-V---DC-ET---DQCCQS-DCKFKL-GANCSTG------L
CCH--ECHFHPSGYVCRKEES-ECDLPEYCDGASNLCPNDSYKQNGTPCKY--D-AIC--
---YDKRC-QSRFL-------------QC--QSIFGP---DA---KEAPS-----QCYEA
VNLVGDQFGNCDIL-G-----------------TRTYRKCEQDNFVCGRLQCINVKTIPD
LPE--HT---SIINTHL--QKE-NLMCWGT----------------GY-HSAMT------
-------PLGIPDMGVIHDGASCGHN---------LVCFN---RTCTNMSI-LQY--DCL
P-EKCNR-RGVC-----NN--RRN-CHCMYGWS-PP----------FCED----------
-DG---YGGSIDSGPPGP---LIV------------------------------------
--------------------------------------E----IPSSIR-VVFIML----
-LRLIFLIIS----V--IVV--IFKSVIG-KSLSSE---SKD-T-PAS------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------QEYGFITLDADA-K---ALMRVTL
L--LLYL-----------KVFL--------S-PN------VL-----P-Q-TGSI-QYLS
SPE

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

VVIPLKVTSRAR-----GA--------KNSGW-LSYSLVFGGQRHVVHMRV-K----
----N-MLVSTHFFVLT--HTEEHAILKD---YPFV------------------------
----PSDCYYHGFVEGAPES-LVAFSACNG--GF----Q--GVLQFNGFSYEIEPIS-HS
-STFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YTLNNN-KI--QFPPMMCGLTEKR-M-----PYQHLGL-E-DA-----ERSA
MK-------QNSG-KSWTRTW

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

FLELAVVVDYDFFTYCQR-NLSKVREDVVLIVNMVDSMY
KQLDTYVTL------IGIEIWNRGNVFP-ME------DIQQVLEDFSKWKQISLS--QVP
-HDAAHIFI----RSSP-----IS-VLGI------AY--VAGICHPP-LDCGVENF----
QGDSW-SLFANTVAHE-LGHTFGM-QH--DE-----------ELCSC--GE-RGCVMSSF
RVP---AVRFTNCSYSDFMK---TTLNQG--ICLHN--HP-R--PERV---FL----VKR
CGNGMVEE--EEECDCGSV-H---EC-EQ---DPCCLL-NCKLRP-GAACAFG------L
CCK--DCKLMLSGELCRPKVN-ECDLPEWCNGTSHQCPEDGYVQNGVSCGV---SAYC--
---YQKQC-NDHDQ-------------QC--REIFGK---GA---RSAPH-----DCYKE
MNSQGNRFGHCGTN-------------------GTVYLKCRMSDIFCGKVQCENVKDIVH
LQA--HF---VLQNTYA----N-GVTCWST----------------NH-HLGLG------
-------V---PDVGEVRDGTTCGAG---------KICVH---KKCISLSV-FSN--ACL
PE-TCNR-KGIC-----NN--KHH-CHCDYGWS-LP----------FCLH----------
-RG---YGGSIDSGPTSP---KRSVNII--------------------------------
-------------------------------------------------QLSIIVT----
-VFSLLTC---------MLITKAC------MPG---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLVLL-------TGLGGMH--A---------------------DL-----NPHK--I
F

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 428)

LQTTIPEKISSSDA----KAD--P-------EHN-VVYMITIEGKPYFVHLKK-H--MF
FIILRCSILSSASFIHS--YDKNDFRHSK---PLLV------------------------
----QMDCNYNGYVAGIPNS-LVTLSVCS---GL---RL--GTMQLKNISYVIEPME-AV
-SGFIHK

ENSGT00910000144019_0_Linker_1_3 (428, 501)

IYEEKFA-DT-N-I-LLEEN----D-T----YSWF--N--S-E------YQVR
KS-------SEKTDFIKLFP

PF01421 // ENSGT00910000144019_0_Domain_3 (501, 546)

RYIEMHIVVDKNLFDYMGS-DINAVTQKVIQIIGLVNTML
TQLQLT---------------------------------------------DHLN---FK
PHQIAYLFV----YRKL-----PT-LIGA------TF--PGQICNKD-FAAAV-AL---Y
TEGLSLESYTVIIVQL-LGLNLGL-TYD-KT-----------DTCHCSG---DVCTMTPK
AVYSGGVKDFSICSLDDFKYISSH--NGL--TCLQT--NL-P--EMPT-YTQ---R--RI
CGNGLLEG--GEECDCGNN-N---NC-TH---KLCCEPLTCRLKG-NALCGSG------D
CCS-KDCKFKPANTICRKSVDEECDFTEFCNGSHPYCLLDTYVR

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1068)

DGEYCDS-GG-AFC--
---FQGRC-RTFDK-------------QC--DDLIGR---GS---RGAPI-----FCYDE
INTRGDKFGNCGTE------------------------YCLFQHILCGKLVCTWEHKDLI
SRP--N---LSVIYAHV----R-DQTCVST----------------YL-PRRKPPPVQAS
VSSTSYYSVDDRDETFVQDGSVCGPD---------MYCFK--M-RCKHVRF-LMNFEMCE
ASNHCNG-HGVC-----NN--FNH-CHCEKGYN-PP----------YCQP----------
-KK-E-AFGSIDDGHLVP----TE------------------------------------
------------------KL-HGG-G---KTCPF-------SKQHFQLIFYISLPV----
--LIIT---------T-AILIKRKKL------RELC----Y---RGETESESS-------
-VSEESSSD-------NKSSLSER------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------F-------------SGSLF
H--FL-L--------------L--PL--------------------MS-----YTES--S
FVQVVFPEKV

PF01562 // ENSGT00910000144019_0_Domain_1 (251, 429)

EDSTS---------S-------EEQ-VTYIIPIDKKRYTVRLQR-S----
------YFLADRFMVYS--YKK-GFVTTQ---SLDI------------------------
----PSQCYYQGYIEDYPNS-IATISTCS---GL----R--GILQFENVSYGIEPLE-ST
-VRLQHIIYKLENEGND-D-LSVFNTN----S-R----NIQI---P-Q-N------YDIL
IN-----EKVKSP-LKQLFPLYLEMTIVVDKALYDYLGY-DSMIVTNKIIDIISLINSVF
SQFKVTVVL------SSLELWSDRNRIS-TV-----GEADELLHRFLEWKKSYLT---LR
PHDIAYLFV----YNEY-----PN-YVGA------TY--PGKMCMEQ-YSAGI-TM---Y
PQNMTLEAFSVVVTQM-LGLSLGI-SYD-DP-----------AKCHCPE---TVCIMTPT
AVQSTGMKVFSNCSLSDFEHFISN--VGA--KCLQN--KP-Q--MQT----SP--R--PV
CGNGRVEG--NEICDCGTE-Q---QC-GP---DSCCEPTTCVLKQ-GNLCDSMSPSQ--T
CCQ--DCNFVEQNQECRPPKHPDCDIAEVCNGSSGACPPDITIH

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1072)

NGHTCKE-GG-FIC--
---FDGDC-PDLDK-------------RC--EEIYGE---GS---RNAPF-----SCYEE
IQGQTDRFGNCGKDRQ------------------NRYVFCGWRNLICGRLICTYPKQTPY
NPP--NSSTASVIYAFV----R-DQVCISV----------------DF-GSSV-------
----------REDPLRVISGSVCDLD---------RICLN--N-ICVETRF-LKNQSSTC
S-SKCNG-NGVC-----NS--LGE-CHCNEGFG-PP----------DCST----------
-S----VRSSWWFNKN------D-------------------------------------
--------------------LTME-G--S-P-KN-------SEKKWLLSLYIVLIV----
--FTST---------VLVL-TVWKGL------KPWL----F--KEEESMSSEC-------
-ASWPYTIL-------STSVPEKTVTVHL-----SC--------------------EIIT
Y-----------------------------------------------------S-----
-------MSPCQ------------------------QKN---------------------
------------------------------------------------------------
------------ILMYLL---------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLLLV-------LHLNGLQ--A---------------------GQ-----NPQR--T
TLQTTV

PF01562 // ENSGT00910000144019_0_Domain_1 (247, 429)

PEKISSLDV----ETD--P-------ENH-MAYLITINETPHFIHLKK-Q----
------SFIMSTAEVYT--YDRNDVRHSQ---PLSA------------------------
----LENCNYNGYVAGFPNS-IVTLTICT---GL---R---GTIQFENVSYAIEPVE-TL
-SGFVHVIYENTNK-HA-V-IPDLGKN----Q-S----YGWS-DE--S-D------YQFR
SN-------MKKAGFIMLRQRFIKMDIIVDKKLFDYMGS-DTKVVLQKVIQIIGFVNTML
SKLKLTVVI------NSIEIWSKENKIN-FS-----EAPNDLLVQFSIWKH---E---YR
PHHVAYLLA----FEEH-----PA-STGA------LY--PGNLCKLE-YNAAV-AL---Y
PKGLSLESFSVIVLQL-LSISMGL-TYD-T------------ENCHCTG---DVCLMTPR
AMNLGKLT----------------------------------------------------
----------------NIR-K---NC-TH---RKCCDPMSCRLKT-KAACGSG------E
CCN-QDCTIKVSDVICRKSID-ECDFVEYCNGKDAYCVPNTYAR

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1067)

NGQYCES-GE-AFC--
---YQGKC-QTADK-------------QC--MNMLGK---HV---RAGSF-----ACYEE
FNSRGDRFGDCVNK------------------------YCTLNNALCGKLVCTWPFKKLV
LKV--N---LSVAYGQV----R-DDLCVSM----------------YK-GGRIP--KP--
-TMSTYSQLSDRDETFVNDGTICGPD---------MFCVG--A-VCRETRF-YINSSGCD
STRDCSD-HGIC-----NN--FEH-CHCDKGYN-PP----------FCEE----------
-HK-G-QFGSVDDGHKYY---VEDG----K------------------------------
------------S---YKQ------S---SHSNL-------PKQRLQLILYISLPL----
--LVII---------S-AIVIKQSKL------SRIC----G---RERSESNSS-------
-TTEDSESN-------TSGTSSGGR-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWA-QAH-LTGDLWL
P--LLWLL---------------LSPVCCSHALP------GW-----R-F---------A
SSEVVI

PF01562 // ENSGT00910000144019_0_Domain_1 (247, 428)

PRKVSHRVS-----GA--------ERQGQ-LSYKIHFRGQRHVVHMKV-K----
----K-SLLPKHFPVIT--DNDQGAMQED---YPFV------------------------
----PRDCYYHSYLEGVPGS-MGTLDTCYG--GL----H--GMLQVDDFTYEIKPLE-AS
-SRFEHVISLLVSE-GR--PSESQRCKIEEQ-------STNQAFEE--------AILSGA
PR-------AAPVYLWWPHKKYLKIHYTVSNTLTVRN-T-NYTRIIENVVILNNILHTIY
KPSLLDVNI------RALCIWDGMDRIN---F-YEFSTIQAAITEYGLWKFYALYD-AIR
-HDTSILLT----GHRL-----FGALYYA------H---HNGMCNPN-WGAAYVCV----
TNYHI-FLAAAISAHI-VGHSLGI-RH--DV-----------PGCHCFRR--EHCVMSPV
PGL---LDMMSNCSYASLHHR-IS--GWD--PCLSI--PN-V--PYRN-FPYV----AAR
CGDLIV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

DR--NEQCDCGSL-K---QC-SK---NKCCKT-NCVLFR-GSDCSEG------P
CCV--KCKFAQPGTICRDQLG-ICDLPEYCDGKTHNCPNDVYTQDGTPCSA---LAVC--
---VRGNC-SDRDM-------------QC--QSLFGF---QI---KDASP-----ECYEH
LNILGDRFGNCGVRVSQG---------------GGRPFKCEEDNVLCGMLHCSNVHEIPG
GGE--HTTFRHIIIPGV----T-EEKCFGY----------------DT-HHG--------
--------TDTPEMGLVVDGATCGPG---------KYCLK---QNCTFYED-MGF--DCD
VK-TCNF-RGVC-----NN--KKH-CHCMKGWK-PP----------SCDE----------
-RG---LGGSIDSGPPPD---REVGLTPKI------------------------------
-------------------------------------------IVKVNK-AVLLLT----
-LRLILFVTS----II-IGREG------D----TES---EAD-SRLCQHRARC-R-----
----AQ-------NHKL-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
P--FLLLL-------SGLSQLT--SA--------------------GH-----HSET--S
LLQITVPQKIGTNTK---

PF01562 // ENSGT00910000144019_0_Domain_1 (259, 429)

DSGA--S-------DTN-VTYDIKINRKTFTLHLEK-Q----
------SFLDSNFLVYS--YNKSGVLYPD---SSFI------------------------
----KGHCFYQGYAGEIPNS-VVTLSTCS---GL---R---GLLQFENISYGIEPLE-SS
-ATYEHII

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YQIKNN-KS-D-FSPIARN----Y-S----TTQF-AA--Q-P------FKIL
VK-------SEKKSEV-LLKR

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 759)

ILKIQVIMDKALYDYMGS-EVALASEKIVYVFSLINNMF
SQLKMTVML------TSLELWSDKNQIL-TN-----GDANEMLQKFVSWKEKKLF---QR
SHDMAYLLI----YRDH-----PN-YIGA------TY--HGMACNPK-FAAGI-AL---Y
PKMITLEAFSVILAQL-IGISLGL-TYKIDI-----------YNCYCPG---TICIMNPE
AIRSRGVKFFSSCSVDEFKSTVSR--PEF--ECLQN--QI-V--PKVV-PQART----GS
CGNGAMEE--GEQCDCGAV-E---NC-IH---KKCCDAANCTLIG-DAECGTG------P
CCDRKTCRLSQRGVLCRRSTD-LCDFPEYCSGTSEFCTEDMRAADFEMCNN-KT-TYC--
---FQGIC-RDRSK-------------QC--LELFGK---FA---ESSSY-----LCAQE
VNIQSDIFGNCDGR------------------------SCNFVNTLCAKLVCHWKHSQIV
PKT--D---FDIQYTYL----D-GHVCMSG----------------NL-RNSST------
-----------PDLTKVWDGTKCDDG---------RFCDN--G-QCRLTQD-YRNRPNCS
SAVKCGG-HGLC-----NT--LLN-CHCDVGYA-PP----------ACEP----------
-EP-LSPGGSINDGFWIV---EGK-NVE--------------------------------
---------------------FLV-K---RHRAS-------QKKGLLISFYVLLPL----
--LVLI---------A-IVALQWNKK------KIFW----N---REDTVSEGS-------
-PSEASSSK-------SDLSCKKSN-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWV-QDP-LTGALWL
P--VLWAL---------------LSQVYCFHDPP------GW-----R-F---------T
SSEIVIPRKVPHRRR-----GV--------EMPDQ-LSYSM

PF01562 // ENSGT00910000144019_0_Domain_1 (282, 425)

RFQ----------------
------------------------------------------------------------
------DCYYDCYLEGVPGS-VATLDTCHG--GL----R--GMLQVDDLAYEIKPL----
----EHVISLLVSE-ER--PGEASRCKTEGE-------ERDQESEK--------VKLAET
PR-------AGHVYLWRHHRKNLKIHYTVTNGLFKRN-P-NVSHIIENIVIINSIIHTIF
KPVYLNVYV------RVLCIWNANDIVM---F-YK-MP------DFGLWKYYEWLS-EIP
-HDNSVVFT----AYRL-----ENLDCYT------T---FDGICNPN-WGAMFVYL----
MRYHL-FMGACLTAHA-LGHNLGL-TH--DS-----------AGCYCFRR--TNCLMAPV
PDL---NDMMSNCSYEEMQNR-LN--KWD--PCLSE--PN-I--PYTN-FPYV----APR
CGDKIKNQ-

PF00200 // ENSGT00910000144019_0_Domain_7 (790, 880)

-REECDCGCL-K---DC-AN---DRCCET-SCILSL-GSVCNTG------L
CFR--E-------LVCRDLGG-ICDLPEYCDGKKEECPNDVYVQDGTPCSA---VSVC--
---VRGNC-SDRDM-------------QC--QALFGY---QV---KDGSP-----ACYQQ
LNRIGDRFGNCGVVLRRG---------------GSKPFPCEEDDVFCGMLHCSGVSEIPG
GGE--HTTFRSILVRDI----K-EEKCFGY----------------EA-HQG--------
--------TDLPEMGLVVDGATCGPG---------SYCLE---HNCTFYQD-LHF--ECD
LK-TCNY-KGVC-----NN--KKH-CHCVFGWQ-PP----------TCEL----------
-RG---TGGSIDSGPPPD---KQYHTASSI------------------------------
-------------------------------------------LVNTNR-VLLLIF----
-THYILFLVS----LL-FGGFS------Q----AIE---FME-EKVLKTTEPE-E-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSAEV-Q---VTLRAPV
L--LLGL-----------WAL--LAPVWCSQGRP------L-------------------
--------KETHH

PF01562 // ENSGT00910000144019_0_Domain_1 (254, 428)

GK-----GV--------QFPGW-LSYSLRFGGQRHVVHMQR-K----
----H-LLWPRHLLMTT--QDDQGALQVD---DPYI------------------------
----PPDCYYLGYLEEVPLS-MVTVDTCYG--GL----R--GIMKLDDLAYEIKPLQ-DS
-RRFEHVVSQIVAE-PN-ATGPTFRDGDNEE--T------DP-LFS---E----ANDSMN
PR--------ISTSLYSSHRGNIKGHVQCSNSYYRIYD--NITTCSKEVVQMFSVIDSIV
QNIDLRYYI------YILTIYNSRDPAP-VN------DYRY-HSPILNYFRRTFFD-TFR
-VHSSTLLI----KDAP-----HESNYEP------R---RYSFCSHL--GLIHIGT----
LDRHY-LLVAVITTHI-LMRSMGV-AY--DY-----------KYCTCQRR--TSCIMQRY
SEM---TDAFSNCSYGHIQNCFVS--I-G--RCIFE--AL-A--PVYN-----ETMTTVL
CGNLIVEG--KEECDCGSF-K---QC-YA---SHCCQS-DCHFTP-GSICHLG------D
CCT--NCSFSPLGTLCRPIQN-ICDLPEYCHGTTLTCPPDFYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1032)

DGTLCTE---EGYC--
---YHGNC-TDRNV-------------LC--KAIFGV---SA---EDAPE-----DCY-D
INLESHRFGHCTQEQN-----------------AIRYQAWVGIDKFCGRLQCTNVTHLPR
MEE--R---QMCILL-K----K-YYR----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 429)

HEIVIPRNLMMFKG-----LE--------EKAEK-VSYVLLIRGKWHIINLKQ-K----
----R-GLFVKNFPVYT--HRN-GKLGLD---MPFI------------------------
----QDDCYYDGYSEGDTDS-LVTVSTCS---GL----K--GILSLHGTVFGIKPIN-TS
-TKFEHMV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YSMSLK-------SSGSCAVNRD-EHEELLTNSQ-FQSRI----------EP
FS-------VSM-SYMWSHP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYIEMFIVVDNKRFQMWNS-NVTKTTQMVMDVHALVNRYM
RELNVKVVL------AGLEIWTERNLVQ-IS-----MNLQETLQNFNQWRNWHLLR-RVK
-HDVAHMII----GQNL-----RK-YQGH------AF--LSGICTDK-NATSVESF----
SHEDI-PRLAALMAHE-LGHNLGM-KH--DH-----------VTCKCHG--QNLCTMHEF
ITA---DMGFSNCSFHYFYQLLHK--HRG--DCLFN--KP-E--LQSS-FG------KSY
CGNKIVDQ--GEECDCGSV-L---DC-QK---DHCCLP-SCRLKK-GLDCAFG------S
CCK--NCKFLKATTLCRPSMD-ECDLPEYCNGTSKWCQADTYKQDGTPCKE---QGYC--
---YHGQC-RSLEN-------------QC--VKIFGR---GT---RVAQE-----SCYHY
MNTKGDRFGNCGSESKGM---------------FKIFHKCKANDVKCGRLLCENIEKLPH
IEK--RN---TIIQFPT----E-DSWCWGA----------------EFFEAT--------
---------DRADEGEVKDGTPCGPQ---------KICVN---RTCLDTTV-LHY--DCN
Q-EKCHG-RGVC-----NN--FKN-CHCAYGYA-PP----------TCES----------
-EG---YGGSLDSGPASH---VPSDSQYGKMLKIL-------------------------
--------------------------------------------------IWVLPI----
-LLLFLILT-----TF-LFVYIHRRSKT-----------SVN-T--KNSSEQQD------
E-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------M-FH--DE-----------KYCHCPR---RQCIMAAL
H-S--VTDLFSNCSYNYYYNQMIS--S-A--GCLLK--PP-A--SKEV-YT------RKY
CGNQMVES--GEQCDCGSK-Y---NC-RK---DPCCQS-NCTLSA-GATCAFG------E
CCE--DCQILPAGTLCRKSNN-KCDLPEYCNGTSQWCQKDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGAPCEK--G-AYC--
---YGGNC-SSHDQ-------------QC--KMIFGK---EA---IVAPL-----ACFQK
LNMHGDRFGNCGIT-REM---------------NAKYKKCQADDILCGRVQCENKKIIPS
LQD--HS---TILQTPV----D-SNWCWGT----------------DY-HHG--------
--------MEIDDIGAVRDGASCGPD---------KICVN---MSCVNLSL-LNN--DCN
A-TKCHK-RGIC-----NS--HKN-CHCDYGWA-PP----------YCQD----------
-KG---YGGSIDSGPPPR---VKA------------------------------------
----------------------------------L--GG----GAIAT---LI-L-----
--LAAAAA------LG-IGFGVYYKTAL-----MGW---FRR-SMARFH---------AT
QQTGASSQGVHASSH---------------------VKPATMS---KPRLESMQ------
----EALDFM--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MFLLL-------VLLGVFY--A---------------------GP-----SFQQ--T
P

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 429)

LQITVPRKIWSNAT----EDS--V-------EQH-VAYIITIEGKPYTLQLQK-Q----
------IFLPQDFMVYT--YNKQGVFHSSSSSSSKV------------------------
----MMQCNYHGYVAGFPNS-LVTLNTCS---GLRIFR---GLLQFENISYGIEPLE-ST
-AGFEHIIYQIKNE-NI-N-VPLLEEN----D-T----DIWY-KN--L-P------YKSH
ID------LEEKIMVSHLLPRYLEMHVIVDKALYDHMGS-DMTVVTQKIIQIIGLVNTMF
TQLKMTIVL------SSLEFWSDKNKIS-TI-----GDANDLLHRFLAWKQKFLV---LR
PNDMAYLLV----YRNR-----PN-YIGA------TF--PGKICNKS-YSAGI-AM---Y
PKAVTLETFSVIMVQL-LGLNLGL-TYD-DL-----------NMCHCLG---ATCIMNPE
AVHSSGIKVFSSCSLKDFKHFTSK--SGV--ECLQN--QP-Y--VTPV-YKE---D--AV
CGDGFV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

EG--DEECDCGPK-EEYPMC-KF---KNCCVMETCKLKP-SAKCGFG------P
CCS-SSCQFYKRGKLCRPKASEECDFNDFCNGTSHECVPDTFVQNGESCRK-KT-AFC--
---VNGLC-ANIND-------------QC--KAIFGS---GS---KGASF-----ACFEE
MNGRSDRFGNCGVKK-------------------DSFKPCPFEDLLCGKLVCTWPKRTLF
FRS--D---VSVIYTRV----Y-DDICVSL----------------AH-RIP--------
------VRPGQRDFTFVNDGSPCGPK---------MVCSH--F-TCRESRF-LMQ-ESCN
ATEKCHG-KGRC-----NN--FNS-CHCNTHYS-PP----------DCKR----------
-MA-FLSGGSYEDGHLAR---PEIRPLSEK------------------------------
------------I-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MRPAGRT-L---PSQSL

PF01562 // ENSGT00910000144019_0_Domain_1 (179, 429)

WL
P--ALLLQ-MLL---GALSNDV-------IF-QP------DS-----G-F---------A
SYEITIPKKLSYRVG-----EQ--------GLVQH-LSYLLHIQGKKHVLHLRP-K----
----R-LLLPRHLRVFS--FTHQGELVED---HPYI------------------------
----PRDCNFMGSVEGSKES-QATFSTCMG--GL----R--GVLKVDAQDFQIEPLR-TS
-STFEHIV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YLLKEE-E---PFLSQNCDLVDDEEI-----KKL-MSP-K-DYM--A-----
-R-------IRSIKASYKHP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYMELVLVFDHDRFLYSKS-NITKVTNDAILISAILDTYY
QDVFTRIHL------TAVEVWTDRDKAR-IH----HRTISRALGQFSVYRTSNLLV-RIP
-HDWTHLFA----IKDY-----VK-GLAS-----------GGMCWL--ASVSLAIL----
KDENI-LGPATWTAHE-IGHGLGM-DH--DG-----------LECLCKGR--RNCIMGSG
------RTGFSNCSYEEFLYFTNS--E-A--ACL-D--IP-G--QGL---V------IXX
XXXXXXXX--XXXXXXXXX-X---XX-XX---XXXXXX-XXXXXX-XXXXXXX------X
X-X--XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX-XXX--
---XXXXX-XXXXX-------------XX--XXXXXX---XX---XXXXX-----XXXXX
XXXXXXXXXXXXXX-X-----------------XXXXKNDLRKISLWDTTHCLPAKNLLN
STD--HA---TIMSTHL--KEE-NLMCWTI----------------GY-HLNMR------
-------PLGIADAGVISDGTSCGKD---------RVCFN---RSCVN--V-LNY--D

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CL
P-KKCNN-RGVC-----NN--KKN-CHCLYGWA-PP----------FCEE----------
-EG---FGGSIDSGPAGP---LEK------------------------------------
--------------------------------------E----VSANIQ-IVSIMF----
-LRLALFIIS----L--VIL--AFWNVID-SYIIPK---PET-QLQRISTDIVKNQ----
NM----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSVWA-F---LPQHRWL
-----FLT-MLF--LEAVGEE------DLLF-DP------DW-----G-F---------D
SYEITIPKVISFKKG-----AQ--------GV

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

DSS-LSYLLQIEGKARVVHLRP-K----
----K-LLLPRHLPVFS--FTQEGSLIED---YPHI------------------------
----PDQCNYVGSVEGSQES-ESTLSTCMG--GL----R--GVLNIDSRYYQIEPLR-AS
-SSFEHVVYLVT-E-D---NFNNETCGVVDEE-T-----GGQ-TAE-E-EEM--A-----
-R-------ISSFHQSYKHQRYLELVMVFDLDRFVFARG-NMSRMVDDAILLASIADTYF
QDVSLKIQL------KALEVWTYYNRIR-LY----YPSLSEVLGQFVHYKRNSMHH-RLP
-ADWFHLYI----ARRY-----ID-ANAW------SW---GRACEEF-HAGSASSF----
LNVNI-LGPATWTAHE-LGHCVGM-IH--DE-----------EFCQCRGR--KSCIMGTG
------RTGFSNCSYHQYFLHAS--YKMS--YCLSD--FP-K---LH---I------VER
CGNKIVEN--KEECDCGSK-E---DC-KK---DLCCGP-DCKWKE-GVNCSSG------L
CCH--KCNFLPSGYVCRKEVN-ECDLAEYCDGTSGVCPDDSYKQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1072)

DGTPCRN--G-GFC--
---FRKGC-RSRYL-------------QC--QSIFGR---KA---KEAPH-----QCYEA
VNMLGDQSGNCGIV-N-----------------ATRYTRCHRGNTICGRLQCINVKALSK
FPD--HT---IILSTYL--RGD-NLICWGT----------------SY-HGTMI------
-------PHGVPDIGDISDGTSCGRN---------RVCLN---RTCVDYTN-LKF--DCL
P-DKCNS-RGVC-----NN--RRN-CHCSYGWE-PP----------FCVE----------
-VG---YGGSLDSGPPGP---RIE------------------------------------
--------------------------------------V----LSTTS----ALYM----
-LRTILFLVS----M--IVV--CLGQLIR-NLFRNR---RRN-LQQKNPAET--QGMKR-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------SQN--S
FLQIVSPEKLQEDTN--NNSEQ--N-------DEQ-LSYIIPIDKKLYTVHLQKXX----
------XXXXXXXXXXX--XXX-XXXXXX---XX--------------------------
----XXXXXXXXXXXXXXXX-XXXXXXXX---XX---XX--

PF01562 // ENSGT00910000144019_0_Domain_2 (402, 488)

GILQFENVSYGIEPLE-LA
-VEFQHLLYKYKNE-IN-E-FPIFTES----S-R----SLET-Q-P-K-D------QNNF
LN-----KKTDSG-ALKVFS-FYVMHIVVGXXXYDYLGS-DDVIVTNRIFEIIGLVNLXX
XXXXXXXXX------XXXXXXXXXXXXX-XX-----XXXXXXXXXXXXXXXXXXX---XX
XXXXXXXXX----YREY-----PN-YIGS------VF--PGKMCDNH-YSTGL-AL---Y
TSKITLEAFSVVVSQL-LGFSLGL-SYD-DP-----------KECHCSG---TICLMNLE
AAQSSGVKMFSNCSLNDFENFISN--MHA--TCLQN--KP-L--MQR-----K--P--PI
CGNGKVEG--NEVCDCGTK------C-AP---DTCCNPKTCQLKE-GATCLKG------L
CCK--DCKIAQSGTECRPSVHAECDIPEFCNGTSPMCEPDITIH

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1008)

NGHLCKS-KK-FMC--
---FNGDC-HDLDE-------------RC--EKTFGK---GS---KNAPF-----ICYEE
IQSQVDRFGNCGWELY------------------FGYVYCLWSDLMX

ENSGT00910000144019_0_Linker_9_10 (1008, 1140)

XXXXXXXXXXXXX
XXX--XX---XXXXXXX----X-XXX--XX----------------XX-XXXXX------
--------XXXXXXXXXXXXXXXXXX---------XICVE--G-ACVESRI-LEGQSKD

PF07974 // ENSGT00910000144019_0_Domain_10 (1140, 1188)

C
S-NKCHG-NGVC-----NS--KEE-CHCFEGFK-PP----------DCQT----------
-RG---RGFARLPGVEGX---XX-------------------------------------
--------------------XXXX-X--XXX-XX-------XXXXXXXXXXXXXXX----
--XXXXXXXXXXXXXXXXXXXXXXXX------XXXX----XXXXXXXXXXXXS-------
-KSEISTHT-------RDSRFTSETSK---------------------------RTDTSK
S---------KSEGSICTS--------------------------ISSSKSQEST-----
-------QTLTS------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLALL-------TELGRLQ--A---------------------HE-----GSEG--I
FLHVTVP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

QKIKSND-----SEV--S-------ERK-MIYIITIDGQPYTLHLRK-Q----
------SFLPQNFLVYT--YNETGSLHSE---SPYF------------------------
----MMHCHYQGYAAEFPDS-FVTLSICS---GL---R---GFLQFENVSYGIEPVE-SS
-ARFEHIIYQMKNN-DP-N-VSILAVN----Y-S----HIWQ-KD--Q-P------YKVP
LN-------SQIKNLSKLLPQYLEIYIIVEKALYDYMGS-EMMAVTQKIVQVIGLVNTMF
TQFKLTVIL------SSLELWSNENQIS-TS-----GDADDILQRFLAWKRDYLI---LR
PHDIAYLLV----YRKH-----PK-YVGA------TF--PGTVCNKS-YDAGI-AM---Y
PDAIGLEGFSVIIAQL-LGINVGL-TYD-DI-----------TQCFCLR---ATCIMNHE
AVSASGRKIFSNCSMHDYRYFVSK--FET--KCLQK--LS-N--LQPL-HQNQ-----PV
CGNGIL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ES--NEECDCGNK-N---EC-RF---KKCCDYNTCKLKG-SVKCGSG------P
CCT-TKCELSIAGTPCRKSVDPECDFTEYCNGTSSNCVPDTYALNGRLCKL-GT-AYC--
---YNGQC-QTTDN-------------QC--AKIFGK---GA---QGAPF-----ACFKE
VNSLHERSENCGFKN-------------------SQPLPCERKDVLCGKLACVQPHKNAN
KSE--V---QSTVYSYI----Q-DHVCVSI----------------AT-GSSMR------
--------SDGTDNAYVADGTMCGPE---------MYCVN--K-TCRKVHL-MGY--NCN
ATTKCKG-KGIC-----NN--FGN-CQCFPGHK-PP----------DCKF----------
-QF-GSPGGSIDDGNFQK---SG-D-----------------------------------
--------------------FYTE-K---GYNTH-------WNNWFILSFCIFLPF----
--FIVF---------T-TVIFKRNEI------RKSC----N---RENAEYNRN-------
-SSVVSE-S-------H-------------------------D---VGH-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSGWT-L---FPESHLL
P--LIVLV-ALL--LDALGEGL-------IF-HP------EW-----G

PF01562 // ENSGT00910000144019_0_Domain_1 (229, 429)

-F---------E
SYEIIIPKKLSLRGG-----PQ--------GAVQQ-VSYLLQVKGKKYVLHLWP-K----
----R-FLLPRNLKVFS--FSKQGKLLED---HPYI------------------------
----PRDCNYIGLVEGTQDS-EATLSTCTG--SL----R--GILRIEEDRYQIEPLR-AS
-SSFEHVMYLLKTD-G---KFQNQTCGLTNDD-L-----EEK-MAQ-T-ENR--A-----
-K-------LRDSPRSSLHPKYLEIALVFDYKRYLFSDA-NVTRVIQDAILLTGIMDTFF
KDINMRIIL------QGVEIWTENDRIN-IP----QLSSQELLNTFLKYRTANLSK-QIS
-ADWAHLYT----THNL-----TH---SF------GGTYIGGVCKDK-YSGSVSSF----
TNANI-LEASRISAHE-LGHGMGM-KH--DT-----------LYCKCRGK--STCIMGLG
------SSGFSNCSYSEYFDHIQ--TG-A--ECLNN--IP-G--LGY---V------VER
CGNKIV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

EG--TEECDCGSR-E---DC-KN---DRCCQP-DCKFVQ-GADCNTG------L
CCH--NCRFRPLGYMCRKEDN-ECDLAEYCSGISNFCPNDTYKHDGTLCKR--N-SLC--
---FKKRC-NSRYT-------------QC--QNIFGS---DA---REAPE-----QCYQA
VNLMGDQYGNCGLK-G-----------------YR-YKACTKENALCGRLQCINVKHVPD
MPV--HR---ALISTHL--RAE-NLMCWGV----------------GF-HESLE------
-------PTGISDIGVINDGTPCGFG---------HICVN---RTCVPTSS-LKF--DCP
P-SKCNL-RGVC-----NN--KRN-CHCTYGWA-PP----------FCEE----------
-VG---YGGSIDSGPARQ---LKE------------------------------------
--------------------------------------D----MPAPVQ-VVSIML----
-MRLIFLIIS----V--IAV--FFRRLIK-QYITPA---ERE-ATPIN------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
P--FFLVL-------SCLCQLI--IA--------------------GQ-----ESET--P
LLQTTVPQKIES

PF01562 // ENSGT00910000144019_0_Domain_1 (253, 429)

NIK---DAKA--A-------EAQ-VSYLVRIEGKAYTFHLEK-Q----
------SFLHPSFMAYS--NTKSGKFQTD---TSLV------------------------
----KVHCFYQGHAAEIPAS-TVTLSTCS---GL---R---GLLQLENITYGIEPLE-SS
-ATFEHMIYQIKNN-KI-D-YSPLREN----L------NSQH-ES--Q-S------YRIL
VK-------PEKAENVSLMKRTLRVKIVMDKAMFDHLGS-EMGVAVQKVVHMFGLINTMF
SELKMTVML------TSLEIWSDENKIE-TN-----GDADEVLQRFLVWKQNQPS---ER
VKVIMYLLL----YKDY-----PD-YMGA------TY--HGMACNPK-FTAGI-AL---H
PKTLTVEGFAAVLSQL-LGINLGL-TYD-DV-----------FNCFCPG---STCIMNPS
AIRSQGIKVFSSCSMDAFKQLASQ--PDL--DCLRE--KP-E--PEFE-ALPQI----RI
CGNFKLDG--

PF00200 // ENSGT00910000144019_0_Domain_7 (791, 880)

YEQCDCGPA-E---KC-TH---KNCCHPENCTLTR-SAQCGTG------A
CCDKRTCKIAERGRPCRKSTD-LCDFPEFCNGSSEFCVPDTKSADLELCNN-KT-AYC--
---YGGIC-QDLDR-------------QC--MDIFGK---HA---KGANY-----LCVEE
VNNQHDKFGNCHG-------------------------HCKYDELFCGKLICYWNHEKII
H-K-ES---YDIQYTYI----G-GQVCVSA----------------HL-RDG--------
---------NAQDDTYVREGTICGEG---------KACSQ--G-KCLRVHY-LKRDSACN
SDDKCQG-QGVC-----NN--RDH-CHCEPGFA-PP----------ECDM----------
-TP-SSPGGSLDDGFWLP---LD---RR--------------------------------
------------------TPLVVK-R---R-DTR-------FKKGLLISLYVFLPF----
--LIMI---------A-IIVIKWNIT------HSFW----K---KE--------------
----EFKSG-------FWHFFVIFFLMTM-----F------------ITL-KT--TLSLL
Y----------------------------------------------RSTSEDSN-----
-------KAEG-------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------IMAFSF
P-

PF01562 // ENSGT00910000144019_0_Domain_1 (183, 429)

-FIICQ--V---IVALTIDL-------------------------N-L-----TDWLG
SYEIVTPLLVEERIV-----NK----------TRE-LTYVIMIDRTDYVIHLIR-N----
----P-MLVPTDFKVFS--YNKAYSLYFD---EPHI------------------------
----LTQCYYQGYIQGYPNS-VVAMNTCSGLSPI----R--GIMHTDEFIYAIEPSQ-QL
-DNFKHVAYSMEQF-K-----TTIHCLLNTSI---------------Y-------HPL--
TK-------SSPIEQGLVHYEFTNSDILLLYLQFEFHHE-NQTLLLESMLDLINGVNAVY
QALNSHIVL------VGIEIWSNENLIN-TA----GKNVHAILSDFLAWKREYLDE-NIK
-CAVAVLSW----RDET-----VS-TSSL------SH--LRGACSPD-NSAFIIKM----
NLEKP-VLSLNLFTHE-LGHILGM-KH--DT-----------RGCTCKSGK-AACVMANS
G-L--LSLGFSDCNEKDMEMFFVS--SEA--SCLWK----------------E----LSQ
CGNNILEQ--GEECDCGSV-Q---EC-AI---IKCCDPTTCKLRE-NAECLSG------L
CCK--DCRLLPKGTLCRIPKT-ECDLAEYCDGASSHCPLDMYQQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

NGSPCNN--GTSLC--
---YENTC-YDYNK-------------HC--ETVFGE---GA---TVAPL-----SCFQS
VNTIGDRFGNCNTE--------------------REMVECNIMNVMCGRLQCQNVSSQMK
PID--NKT--AIILTPN----R-NSWCWGI----------------DF-HSN--------
--------QHSFDLGT

ENSGT00910000144019_0_Linker_9_10 (1097, 1139)

VPDGAPCDTG---------KICLN---KRCLSSSV-LSY--D

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CD
VKRKCGG-NGVC-----NN--RKN-CHCYSQWA-PP----------NCTE----------
-SG---YGGSVDSGPVTK---DSS------------------------------------
----------------------------------L--VF----MPEGGMLRLYDTSAARC
PRLPVFIIIL----YQ-TLLIECFQ--SI-YYLTLW------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
S--LLLLL-------TGLGQLA--SA--------------------GH-----QFET--A
RLQITVP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

RKIETNTK---DGSI--S-------ETH-VSYSIQIDKKTYTFPLEK-Q----
------SFLDSNLLVYS--YNKSGVLYPD---SSFI------------------------
----KGHCFYQGYATEIPNS-AATLSTCS---GL---R---GLLQFENVSYGIEPLE-SS
-TTYEHVIYPFRDK-KS-D-FSPISEN-----------------N--Q-S------YKIL
VK-------SNKDSGV-LLKRVLKIRVIIDKALYDYMGS-EVTLASEKIIYVFSLINTMY
SQLQVSVIL------TSLEIWSDLNKIS-TD-----GDAHEVLQRFVSWREKNLL---QS
SHDLTYLLI----YRDH-----PN-YVGA------TY--HGMACDPK-FAAGL-AL---Y
SKMITLEAFSVLFAQL-LGIMLGL-KYNNNI-----------YECSCPG---IACIMNPE
AIRSHGIKYFSSCSIDEFKHMTSQ--PKL--ECLQN--QT-V--PKVF-PQGRQ----SI
CGNGILEP--PEQCDCGAK-E---TC-EH---SKCCDPLNCVLKG-KADCGSG------P
CCGKNTCKIFERGRECRKSTD-PCDFPEFCNGVSEFCAPDMRAA

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1072)

DLQTCNN-KS-SYC--
---FGGIC-QDRTM-------------QC--INLFGK---FA---EESSY-----QCTEE
VNYQDDVFGNCRGK------------------------VCYFRQLLCGKLVCHWTHSAIV
SRN--D---IHVQYTFL----G-GHICMSA----------------DL-RAHRY------
-----------PDPTVTANGTMCDEN---------KFCQR--G-ACTLLHE-YDQYQHCD
PLAKCKG-HGIC-----NS--RLH-CQCDAGYV-PP----------NCAE----------
-FN-SSPGGSIDDGFWDI---QEMEEES--------------------------------
------------------KTAALI-K---RRRAS-------QKNNLMISFYVFLPF----
--FILM---------A-IVALKWNKM------KIFW----N---KEGTLSGE--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--LLLIL-------TGLSLLT--TA--------------------GP-----NSET--P
VLQITVPRKIQTN

PF01562 // ENSGT00910000144019_0_Domain_1 (254, 429)

TD---DGDV--S-------ETH-ATYSINIEGKSYTFLLEK-Q----
------SFLHPRLLVYL--YNESGILHED---SSFS------------------------
----NDHCFYQGYAADIPKS-AVTLSTCS---GL---R---GLFQLDNISYGIEPLE-SS
-PTYEHVVYQIKND-AI-G-HYSFQEN----Y-P----VAQY-ID--Q-S------YRIL
VK-------SDINSGAMLLKRTLKVQIIMDKAMYDYMGS-AVAVAVDKVFQIFGLINTMF
SQLNMTVML------SSLEIWSDQDKIS-TS-----GHADELLQRFLSWKQKFLS---QR
PHDMTYLLV----YRNH-----ST-YVGA------TY--HGMACDPK-FAAGI-AL---Y
SKKITLEAFSVVMVQL-LGINLGL-TYD-DI-----------YNCYCPG---TTCIMNPD
AIRSNGMKFFSSCSMDGFKQIVLQ--PER--KCFQD--KT-I--SKMT-YQGKA----TT
CGNGIL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ES--TEQCDCGNV-E---GC-NF---KKCCNPKDCTLIN-FAECGTG------P
CCDNKTCRIHERGHICRDSVD-MCDFPEYCNGTSEFCVPDVKAADLEYCNN-KT-SYC--
---YEGVC-RDRDK-------------HC--VDLFGK---FA---KSASL-----LCTEE
VNFLNDKFGNCGA-------------------------RCHFFHILCGKVVCHWTHSQPV
SVK--E---YDIQYTYL----G-GHACFSA----------------HA-RNGSK------
--------QV---TTYVEPLTMCGEH---------RACYA--K-QCKFISE-INI---TK
CNKTCKG-HGVC-----NE--HFN-CQCDPGYA-PP----------HCDP----------
-SI-SSPGGSIDDGYWFS---S---EKE--------------------------------
------------------E-PSFP-K---QRAAP-------KNNGLLISFYIFLPL----
--LILI---------A-VVSLKWKKM------KRFW----S---KVGTVSSKS-------
-ISEDSSRT-------NSQSQS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAGGKT-L---VYVRISL
L--LLWL-----------EVFL--------F-LS------GS-----S-Y-IEHS-

PF01562 // ENSGT00910000144019_0_Domain_1 (237, 429)

QRHG
LPEVVVPLKITYNGS-----GV--------KPPGW-LSYSLRFGGQRHILHVKV-N----
----K-LLFSKHLPVFT--YTDQHGLTED---QPFV------------------------
----QNDCYYQGYMEGDPES-LVALSTCLG--GF----Q--GTLQIHNVVYEIKPKS-LS
-TSFEHLLYKMVD--DT--ELPPKRCGLTDED-I-----ARQ-LKFLQ-ES-----VNYT
LK-------QSGYIGWWTHRRFLELAVLVDHGRYLYHQS-NTSSVQSEVCMVVNGIDNFL
QSLDVNVVL------VGIEIWSKDNLLP-TT------NISILLEEFCKWKKNSFNT-RLP
-HDIAHIFI----KENY-----GR-LLGL------AY--VGTVCNQL-YNCGVDSF----
LNDKV-QEFAYIVSHE-IGHNLGM-RH--DD-----------NICKC--GS-KKCIMFPS
KTV---TTRFSNCSYASYWN---VV-GKV--SCMRI--SP-N--PENI---FR----QTR
CGNSVVEE--GEECDCGST-Y---TC-AK---DPCCQS-DCALRV-GATCAFG------L
CCE--NCTLMPSGTVCRKVEN-ECDLPEWCNGTSYQCPEDVYMQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGTSCTG---GGYC--
---YEKRC-NERNE-------------QC--RKIFGK---EA---RNANE-----NCYRE
VNSRGDRFGNCGLT-------------------ARSYIPCGIPDILCGRVQCENVTEIPF
LRD--HS---TVHWTRI----N-GVNCWGT----------------DY-HLGMT------
-------I---PDVGEVKDGTECGAN---------HICIE---RKCTFMPS-FQN--DCS
PE-TCNM-NGVC-----NN--RQH-CHCSSEWD-PP----------HCQE----------
-KG---IGGSVDSGPPPG---RE-AQD---------------------------------
-------------------------------------------HHYLLLF-RLTPF----
-FFM--L----------FCLL---------IWLLKK---LKE-LIGQEEKSAPAEPQKKG
KSSNFIL----------------------------------------------EIK----
-------A----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAVDGT-RVY---IRVTL
L--LLWL-----------GVFL--------S-IS------GY-----C-Q-AGPS-QHFT
SP

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 429)

EVVIPLKVSSRGR-----SA--------KAPGW-LSYSLRFGGQKHVVHMRV-K----
----K-LLVSRHLPVFT--YTDERALLED---QLFI------------------------
----PDDCYYHGYVEAAPES-LVVFSACFG--GF----R--GVLKISGLTYEIEPIR-HS
-ATFEHLVYKINSN-ET--QFPAMRCGLTEKE-V-----ARQQLEF-E-EA-----ENSA
LE-------PKSAGDWWTHAWFLELVVVVNHDFFIYSQS-NISKVQEDVFVVVNIVDSMY
KQLGTYIIL------IGIEIWNQGNVFP-MT------SIEQVLNDFSQWKQISLS--QLQ
-HDAAHMFI----KNSL-----IS-ILGL------AY--VAGICRPP-IDCGVDNF----
QGDTW-SLFANTVAHE-LGHTLGM-QH--DE-----------EFCFC--GE-RGCIMNTF
RVP---AEKFTNCSYADFMK---TTLNQG--SCLHD--PP-R--LGEI---FM----LKR
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ER--EEQCDCGSV-Q---QC-EQ---DACCLL-NCTLRP-GAACAFG------L
CCK--DCKFMPSGELCRQEVN-ECDLPEWCNGTSHQCPEDRYVQDGIPCSD---SAYC--
---YQKRC-NNHDQ-------------HC--REIFSK---DA---KSASQ-----NCYKE
INTQGNRFGHCGIN-------------------GTTYLKCHISDVFCGRVQCENVRDIPL
LQD--HF---TLQHTHI----N-GVTCWGI----------------DY-HLRMN------
-------I---SDIGEVKDGTVCGPG---------KICIH---KKCVSLSV-LSH--VCL
PE-TCNM-KGIC-----NN--KHH-CHCGYGWS-PP----------YCQH----------
-RG---YGGSIDSGPASA---KRGVFLP--------------------------------
-------------------------------------------------L--IVIP----
-SLSVLIF---------LFTVGLL------MYLRP---C-SG-PKETK--AHSSG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWV-QDP-LTGALWL
P--VLWAL---------------LSQVYCFHDPP------GW-----R-F---------T
SS

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 428)

EIVIPRKVPHRRR-----GV--------EMPDQ-LSYSMRFRGRRHVIHMKL-K----
----K-NMMPRHLP---------GAMQEN---YPFV------------------------
----PRDCYYDCYLEGVPGS-VATLDTCHG--GL----R--GMLQVDDLTYEIKPLE-AS
-SKFEHVVSLLVSE-ER--PGEASRCKTEGE-------ERDQESEK--------VKLAET
PR-------AGHVYLWRHHRKNLKIHYTVTNGLFKRN-P-NVSHIIENVVIINSIIHTIF
KPVYLNLYV------RILCIWNQKDVVR---F-YQ-RPVGTAIREFGVWKYYKLFS-QIK
-HDTSVVFT----Q-------------------------------------CFVYL----
MRYHL-FRG

PF01421 // ENSGT00910000144019_0_Domain_5 (670, 753)

ACLTAHA-LGHNLGL-TH--DS-----------AGCCCFRR--TNCLMAPV
PDL---NDMMSNCSYEKIQHK-LN--KWD--PCLSE--PN-I--PYTN-FPYV----AAH
SGDKIKNQ--REECDCGSL-K---DC-AN---DRCCET-SCILSL-GSVCNTG------L
CCR--GCKYAAPGVVCRDLG---------------ECPNDVYVQDGTPCSA---VSVC--
---VRGNC-SDRDM-------------QC--QALFGY---QV---KDGSP-----ACYQQ
LNRV-------------G---------------GSKPFPCEQDDVFCGMLRCSGVSE-PG
GGE--HTTFGSILVHDI----K-EEKCFGC----------------EA-HQG--------
--------TDLPEMGLVVDGATCGPG---------SYCLE---HNCTFYQD-LHF--RPG
AL-S-PG-GGAC-----SE--LRS-SHCTLYWV-TE----------RDSV----------
-SK---KKK-----KNRT---QDYRLF---------------------------------
------------------------------------------------------------
--KIFLFLVS----S---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------L-----------GVFL--------F-LS------GW-----L-Q-TGHS-QYSS
PPE

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

VVIPLRVTSTGR-----GM--------STPGW-LSYSLHFGGQRHIIHMKA-K----
----K-LLVSKHLPVFT--YADQGDLLED---HPFV------------------------
----PDDCYYHGYVESDPES-LVALNTCSG--SF----H--GTLQINGIAYEIKPKS-PS
-VTFEHLVYRMASE-ET--QSPRMRCGLSDEE-I-----ARQ-LKL-Q-MS-----DDSI
LM-------QSGYEGWWTHRMFIDLGLVVDHRRYVFLER-NNSNVIKDVLNILNEMNLLL
NGLDVDGVL------TGLDIWDQDDLVT-VD-----NNMVTVLEEFRKWKTQNFNM-RVK
-NDIGHLLS----HQYY-----GG-FLGL------AY--VGVMCNSH-YNCGVDSV----
VG-RSLKSIAHTLAHE-IGHNLGM-KH--DE---------QVQPCKC--EG-RACIMAEA
DNN---SNKFSNCSYSVVWS---TT-KSS--KCMHN--VP-V--AVNL---TPLSPQRMF
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EE--GEECDCGSL-Q---LC-TE---DPCCLT-NCTLIF-GAQCAFG------L
CCK--NCTFMPSGSVCREKND-ECDLPEWCNGTSHECPKDVYVLNGMPCTG---NGHC--
---YEKQC-ISRDE-------------QC--RQIFGK---DS---RSANQ-----TCYRE
INNRGDRFGNCGIS-------------------SGSYVRCKANDILCGRVQCENVTEIPS
LSN--HR---TVHCVQV----R-DSICWGT----------------DY-HVGMT------
-------M---PDMGDVKDGTECGNK---------TMCIN---RRCVPMPL-WTS--DCS
VE-TCNM-SGIC-----NN--KNH-CHCDYGWD-PP----------NCTI----------
-VG---YGGSVDSGPP--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------FDYMGS-EVAVAAEKVVHIFGLINTVS
IYVSFKETFLQIMTISYPDLYVFKLYLS-SG-----GNIVFVFKKIYGFIEK--S---KS
YNVIMLVII----YRDH-----LN-FVGA------TY--HGMACNPK-FAAGI-AL---Y
PQMITLDAFSVVMVQL-IGINLGF-TYD-NI-----------YNCYCPG---ITCIMNSE
AIRSHGVKFFSSCSMDEFKRMVSQ--PEF--ECLQN--RT-V--PEVV-YQGRS----AA
CGNGILEP--PEQCDCGLA-E---EC-TH---KKCCNPVDCTLIG-YAECGNG------P
CCDRKTCLIAERGRLCRKMTD-PCDFPEYCNGSSTACVPDVKSA

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1095)

DLEPCNN-KT-AYC--
---FEGVC-QDPDI-------------QC--AKLFGK---FA---KVSTY-----LCTQE
VNFQADSFGNCGKL------------------------GCNFGSILCGKIVCHWTHSKIV
SVV--D---YDVQYTYL----G-GHICLSG----------------YL-RPETK------
--------GLLEDA

ENSGT00910000144019_0_Linker_9_10 (1095, 1139)

TRMNNGTMCGVN---------KYCYR--G-VCQEASS-YPNRPN

PF00008 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CQ
SERNCSG-HGVC-----NN--LLN-CHCDVGYS-PP----------ICEP----------
-AP-LSPGGSYDDGFWYP---ELPPAKG--------------------------------
------------------E-SLLR-K---RYAAP-------QRNGLLISFYIFLPI----
--LILT---------A-IVALKWDKI-------RFW----N---REGTINGD--------
-CTMEINRN-------KETNFVNRI-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAVDGT-LVY---IRVTF
L--LLWL-----------GVFL--------S-IS------GY-----C-Q-AGPS-QHFT
SPEVVIP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

LKVISRGR-----SA--------KAPGW-LSYSLQFGGQRHVVHMRV-K----
----K-LLVSRHLPVFT--YTDERALLED---QPFI------------------------
----PDDCYYHGYVEGVPES-LAVFSACFG--GF----R--GVLQINGLTYEIEPIR-HS
-ATFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKINSN-ET--QFPAMRCGLTEKE-V-----ARQHLEF-E-EA-----ENSA
LE-------PKSAGDWWTHAW

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

FLELVVVVNHDFFIYSQS-NISKVQEDVFLVVNIVDSMY
KQLGTYVIL------TGIEIWNQGNVFP-MT------SIEQVLNDFSQWKLISLS--QLQ
-HDAAHMFI----KNSL-----IS-ILGL------AY--VAGICRPP-IDCGVDNF----
QGDTW-SLFANTVAHE-LGHILGM-QH--DE-----------EFCFC--GE-RGCIMNTF
RVP---AEKFTNCSYADFMK---TTLNQG--SCLHN--PP-R--LGEI---FM----LKR
CGNGVVER--EEQCDCGSV-Q---QC-EQ---DACCLL-NCTLRP-GATCAFG------L
CCK--DCKFMPSGELCRQEVN-ECDLPEWCNGTSHQCPEDRYVQDGFPCSD---SAYC--
---YQKRC-NNHDQ-------------HC--REIFGK---DA---KSASQ-----NCYKE
INSQGNRFGHCGIN-------------------GTTYLKCHISDVFCGRVQCENVRDIPP
LQD--HF---TLQHTRI----N-GVTCWGI----------------DY-HLRMN------
-------I---PDIGDVKDGTVCGPG---------KICIH---KKCVSLSV-LSH--VCL
PE-TCNM-KGIC-----NN--QHH-CHCGYGWS-PP----------YCLH----------
-RG---YGGSVDSGPASA---KKRGFLP--------------------------------
-------------------------------------------------L--IVIP----
-SLSVLIF---------LFTVGLL------MYLRQ---C-SG-PKETK--AHSSG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MRMAD-RHRS--------LRAPL
L--LLGL-----------WAL--LGPVQAFPDHP------SW-----R-Y---------V

PF01562 // ENSGT00910000144019_0_Domain_1 (241, 417)

SAEVVIPRRHTHSGK-----GL--------QVAGR-LSYSLRFGGQRHIIHLQR-N----
----T-RFQPKNLPVIT--QNDQGALQME---HPYI------------------------
----PLDCSYIGYVEEVPYS-MANIDTCYG--GL----E--GIMKLDDLTYEIKPLQ-DS
-LIFEHIVSQIVAD-VN-ETQPRRRPADKR----------PS-PLD---G----AKGAPD
PR--------IPSKVYVYHPVILKGFIQSPNEVYLKFGS-NRTNTIKFMLRFGGAVKAIV
ENISIIFIV------NGLSIYDTGDPLQ-IN------DFRVPDGTVFQHYQRTFYL-SMR
-PNIAYLIL----LQGP-----YELDVAP------P---YYGVCNDK--HLIFLGL----
RGRHY-FLGAVIGAHQ-LGRAFGL-FY--DE-----------AFCQCQRR--ATCVMFKH
PVL---TDAFSNCSYVHLAHIIGG--LTL--WCLYF--TS-F--TYYN-----ETETKFF
CGNRIVDE--GELCDCGTF-K---QC-YT---NPCCQT-TCMFTA-GSICDGQ------D
CCT--NCTYSPSGTLCRPIRN-ICDLPEYCTGSQLTCPENLYMQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCTE---EGYC--
---YQGNC-SDLTI-------------HC--REIFGE---KA---MKGEL-----DCY-Q
INLKGNRFGHCRRRAS-----------------QKSHIACATTDVGCGRLQCSNVTHLPR
LQE--H---VSFHQSKF----G-NSWCFGV----------------DE-HRE--------
--------TQTLDVGFVRDGALCAPG---------KYCLN---TYCSGSVPSISY--DCE
PQ-KCNF-RGIC-----NN--KKE-CHCHIGWD-PP----------LCKT----------
-KG---AGGSESSGPPPH---LMRTVSQSI------------------------------
---------------------------------------------EPV-RLLRIIF----
-GRIYAFIAV----LL-LGVATNVRSIK------T-----IT-VPEGPAPEA--------
----PP-PT---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--VLLLL-------SGLRALG--EP--------------------L----TNDSER--L
RVQITVPEKMG

PF01562 // ENSGT00910000144019_0_Domain_1 (252, 429)

PLTS----DD---S-------ETE-VSYKIAIEGTTYIVNLTQ-K----
------TFLPYNFKVYG--YDDAGIMKPL---EEEV------------------------
----QNFCYYQGYIEGYPKS-LVIITTCT---GLR------GVLQFENISYAIEPLE-SS
-VGFEHILYQIKQE-NK-D-VSLHTL----KN-T-------D-LKN-M-T------YKIQ
TV-------KPS----SEFFQYIELHLIVEKDLYKHLGS-TTATVTRKIFQLVGLMNGIF
SSFNLTVIL------ASLELWTDENKVP-TT-----GDVNELLHQFQDWKKSYLV---LR
PHDVAFLLI----YREA-----PS-YIGA------VF--QGMVCDKD-YGGGI-AL---H
PKSMNLDSFAVILVQL-LSLSMGI-TYD-DV-----------NQCHCPG---AVCVMNPE
AIHSGGVKIFSDCSMNDFARFTSK--PMS--QCLQN--QP-R--LQTA-YQ-----G-TT
CGNKIVEA--GETCDCGTE-E---EC-NRSP-PVCCDPITCRLKD-TSKCFTG------D
CCE--NCEFKSSEEICRNRVD-ECDLPEFCNGSSADCQEDLFIL

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1071)

NGHPCGE-NK-WIC--
---MNGKC-VSGKT-------------QC--EAAFGE---GV---DFGTR-----ECYEQ
LNSRNDIAGNCGIRKD------------------GSYTPCAPNNLKCGKLVCVYNKMEVN
RNK--H---ATTIYANI----N-GEVCVSL----------------EY-PLNY-------
---------SNSNEMWVQDGTVCDTQ---------KVCRN--K-ECVADSF-LGY--DCT
PA-TCNN-NGVC-----NN--KKA-CQCYPGYL-PP----------DCSI----------
-KIPVYG-----------------------------------------------------
-----------------AQFDPE--R---HYIKGV-YQ----TKPKNWPFLLIIPF----
--LIIF---------S-VLIAIVVKVYFQ---RKKW----R---TEDYISEED-------
-LESESEHK-------DSKEKSG-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
-------------------------------------------------LLAFLQKNKEV
MYET------------------------NRMFQNWAAQMKGL-VLVLV-PGF-SCVWLG

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

I
V--LV-------------LVLSFLPSFCSNLG-----------------------SAYYS
SYEIVIPKALTVEGR------Q--------DPGEE-ASYVISMQGQKQLIHLKV-K----
----T-DYFIKNFPVFS--YHN-GILGQE---MPFI------------------------
----SHDCHYEGYIEGLPGS-FVSVNTCS---GL----R--GILIKEGKSYGIEPMD-SS
-KQFEHVL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YTMAHQ-------APVSCSVTSK-DSPVVSTSRQ-QG----------SRKPG
GL-------QEL-SYLWSLT

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYVEMFVVVNNQRFQMWGS-NVNETIQRVMHIIALANSFT
RGINTEVVL------AGMEIWTEGDLIQ-VP-----VDLQVTLGNFNSWRQEKLLH-RVK
-HDVAHMIV----GQHP-----AQ-GMGQ------AF--LNGACSSG-FAAAVESF----
HHEDV-LLFAALMVHE-LGHNLGI-RH--DH-----------SACICKD--KPLCLMRDN
ITK---ESGFSNCSSDDFYQFLQE--HRG--ACLFN--NPQR--HKGRWRR------ASY
CGNGVVEG--EEQCDCGS------AC-YT---DPCCDQ-TCSLKG-SAECSDG------L
CCF--GCRLKNKGSMCRSALG-ECDLPEYCDGTSAECPTDTYKQDGTSCGR---LHYC--
---VGGLC-RNPDN-------------QC--MAMYGD---TA---RSAPE-----NCYIS
MNSKGDRFGNCGHPTS-A---------------MSRYVKCFDVNVFCGKIICTNIRRVPS
IKP--HH---TLIQIPY----E-GDFCWSL----------------DVYNI---------
--------TDIPDEGDVHSGTACAPN---------KVCMN---YSCTDHAV-LNY--D

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CR
PAEMCNG-RGVC-----NN--VRH-CHCEAGYA-PP----------DCRT----------
-PG---NGGSVDSGSPGK---IEDENL---SEDERKSH----SVDHGSFG----------
-------------------------R---G-ENRD--ES----KTIG-QLVYVFPL----
-FLLAIFLC-----LI-IGASLGARND-------------FS-QCSQEAPEES-------
---EEAVAQE---EE---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LVVLL-------TGVGGLY--A---------------------GH-----NPHK--T
FVQ

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

TTVPEKISSVDT----RRD--P-------ENN-VTYIITVKGKPYFVHLKK-Q----
------SFLSSASVVYS--YDKDGTQHSQ---PLLP------------------------
----QMDCSYSGYITGFPHS-VVTLMTCS---GL---R---GVMRIENISYGIEPLE-AV
-SGFMHMIYEENND-DT-H-VSLFGEN----D-T----FTWL-NN--T-E------NQVR
SS-------LHKTEFTKLFPRYIEMYIVVDKNLFDYMGS-DVKTVTEKVIQLIGFVNTML
TQLKLTVVI------SAIELWSNTNKFA-TT-----GHPDDVLFRFLEWKHQHVD---PK
PHHISYLLV----FEKH-----PT-LIGA------TF--PGYMCDKK-YDAGV-AL---Y
PMGLSLKSYAVIIVQL-LGLNVGL-IYD-NT-----------DTCYCSG---DTCTMTPK
AVYSGVLTDFSTCSLDNFKLFASH--YGL--HCLKN--NP-L--DKPI-YKQTNPK--KM
CGNSIR

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EE--GEECDCGTA-L---NC-TH---VRCCDPTSCKKKG-SVKCGSG------E
CCT-TNCQLKKANTLCRSSIDTECDFNEYCNGNEGDCVPDTYARDGSHCDS-GE-GYC--
---FGGIC-RTFDR-------------QC--EALFGK---GS---KGAPF-----ACFDE
INSRGDRFGNCGRY------------------------HCEIQHALCGKLVCTWPHKTLI
SRE--N---LSVIYTHV----R-DDICVAG----------------AK-TDGKIIRTT--
-SFTTYLEPTDRDETFVEDGTICGPG---------MYCDK--W-VCRDVQH-LLN-SSCD
PELHCGG-NGIC-----NN--FQN-CHCNKGFS-PL----------ECQL----------
-KK-G-EFGSIDDGHMTK----GK------------------------------------
-------------------NA-LR-A---GYATS-------SKHRFQLIFYIAIPV----
--MMIA---------A-AILIKQNTL------RELY----C---RGGKEHESS-------
-VSEDRSSS-------IISSSIESNTPTD-----FE------S---NTMTDDVPKPSEVA
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----LVLL-------TGLGRLY--A---------------------GN-----SESR--R
DPSTTVP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

ERISSVDT----RRH--L-------EHN-VAYNITLKGKSYVVRLKK-E----
------SFLSSGSVIYF--YDNRGVQRSQ---PLLP------------------------
----EMDCSYSGYVAGFPHS-RVVFATCL---GL---R---GVIQFENVSYAIEPLE-VL
-SGFTHMIYEENND-NT-H-VPLFGKN----N-S----YARI-HN--L-E------SQGR
RS-------VHKTTVSKLSPRYIDMYIVVNKNLVCLSI----------------------
-----FIII------FKALFSLSFL--Q-QN-----------------------------
------------------------------------------LHIL-----DM-WR---Y
TP--------IIFVM----------------------------------------LICLY
FRFASGLKDFSTCSMDNFKYFASQ--YGL--TCLRN--TS-Y--DMPI-YKQFPPRRRRI
CGNSIREE--GEECDCGTL-R---NC-TH---KKCCDPMQCRMKK-GAXXXSG------P
CCT-VDCQFQKANVLCRKSVDKDCDFDEYCNGRSGDCVHDTYAQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1067)

NGHFCDS-GG-AFC--
---FNGRC-RTHDR-------------QC--QALIGG---DS---RGAPF-----ACYDE
VNSRGDVYGNCGRH------------------------QCYIQHALCGKLVCTWPHKQLV
SRV--N---LSVVYAHV----R-DDICVAT----------------TK-TVRKIIRDL--
-SLTTVLLPEDRDETFVEDGTICGPG---------QYCDK--W-FCKE------------
----------IC-----NN--LDN-CHCHKGFV-PP----------ECAP----------
-KK-G-QFGSLDDGHLVE---TTKT----S------------------------------
------------G---FXXXX-XX-X---XXXXX-------STKRFQLIFYIGIPV----
--IIIV---------A-AILIKQNQL------GKLF----C---RGEKEHMSS-------
-VSEDGSRS-------VTLSATESKFPAD-----TE------H---SNKEEDAQ------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLVLL-------TVLRGLH--G---------------------GP-----NLHK--

PF01562 // ENSGT00910000144019_0_Domain_1 (240, 429)

K
FVQTTIPEKISTSEA----IKD--P-------ENN-VAYVITIGGNPYFVHLTK-Q----
------SFLSSASVVYF--YDKNDIQHHQ---PLSA------------------------
----QMDCNYHGYVAGFPNS-LVSLNICS---GL---R---GTLQFKNISYALEPVE-SV
-LGFMHMIYEEKND-IS-A-IPLLLEN----D-T----YSY--ER--S-Q------YKVR
KS-------SERSGHTKLFPRYIDMYIVVDKNLFDYMGS-DINIVTQKIIQIIGLVNTMF
IQLKLTVRI------SSIEVWSDKNKIS-IE-----GPPHSVLYKFLTWKYEFT----SR
PHHIAYLFA----FKEN-----PT-FIGV------TV--PGEICGKI-AVGGV-AL---Y
IEGLSLEAYAVSIVQL-LGLNVGM-SYD-NT-----------EICHCSG---DVCTMSPE
ALQSGGVKDFSTCSLDDFKYFAAY--TGI--ECLHK--IL-P--DEPV-YKQ---R--RV
CGNGIL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

ET--GEQCDCGTP-Q---TC-TH---PDCCDARLCTKKK-NKVCGSG------A
CCT-TSCQIKPVNTPCREAAD-ECDFVEFCTGNESMCVPDTYARNGEPCAS-GD-AFC--
---YDGRC-RSTNK-------------HC--SRLIGE---GA---RGAPF-----ACFDE
INARGDRYGNCGRG------------------------FCLFSHTLCGKLVCAWPYKTLV
SQP--N---LSVIYTHV----Q-DEICASA----------------FL-NAEKL-PRD--
-TFTTVQKPEDRDETFVEDGTICGPE---------MYCLN--F-SCVEVKY-QINTTICS
NAVHCNS-KGVC-----NN--LNH-CHCSMGFA-PP----------NCKP----------
-LP-E-AFGSVDDGHQHK---TG-------------------------------------
------------------KSF-LK-E---RSLGH-------PKHRLQLVFYISIPV----
--FIIA---------A-ALIIKQDKI------RELC----Y---KGELESERS-------
-VSEESSTN-------SKSSPSVRPSL---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------TSVA---ASLRDSTIILPCLYKKQVA
LEE--------------------------IKFEIWDPKMWNW-RIRSV---------LRR
F--FR-------------LLVIFLPSMYC-IG-----------------------PVQYS
SYEIVIPKSLTVKGS-----

PF01562 // ENSGT00910000144019_0_Domain_1 (261, 429)

-E--------EPVEK-TSYMLLMQGQEQLVHLKV-R----
----R-DYFVNDFPVYS--YHS-GILGQE---IPSI------------------------
----SHDCHCEGYIEGVAGS-FVSVNTCS---GL----R--GILIKEKTSYGIEPTL-SS
-KRFEHALYTMAQQ-------APVPCSVSPR-DSQAVSASQQ-QE----------GRKPH
DL-------QAL-SYLWSHTKYVEMFVVVNSQRFQMWRS-DVNETVQRVVDVIALANIFT
RGINTEVVL------AGMEIWTEGDLIE-VP-----GDLQVTLRNFNSWRQEELFP-RER
-HDVAHMIV----GHHP-----GE-TSGQ------AF--LNGACSSG-FAAAVEAF----
QHEDA-LLSAALMVHQ-LGHNLGI-QH--DH-----------SACVCKD--KHFCLMHEN
ITK---ESGFSNCSSDYFYHFLHE--HKG--ACLFN--KP-R--HKGRRRR------DAS
CGNGEV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 879)

ED--PEECDCGS------AC-HS---DPCCEP-TCKLKE---------------
-----HCNFIKEGVVCSFAHH-ECDLSEYCDGISAECPAHSYKQDGTLCDR---IYYC--
---FEGQC-RYPDR-------------QC--LNLYGY---PA---RSAPE-----ACYMS
MNSKGSWFGNCGRATT-A---------------NAAYIKCSSDDIFCGKVLCTDVPALPL
MMS--HY---TVIQVAH----G-DDWYWSM----------------DAYNTT--------
-------------GDDVEHGSYCAPN---------KFCSG---YVCTEYSV-LHH--DCD
SELLCHG-NGVC-----NN--LRH-CHCNDGFA-PP----------DYRY----------
-PG---YGGSVDSGPIVK---VPEILLSTNSP----------------------------
-----------------------------YFTIKA--RN----MNFK-VIIFIIPT----
-FLFILLCS-----PL-AIAYLWSEIEE-----------LVT-S--EKSEE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------TMAVGEA-L---VDIRV

PF01562 // ENSGT00910000144019_0_Domain_1 (179, 429)

IP
L--LLWL-----------GASL--------S-IS------GH-----S-Q-ARLS-QHFP
SPEVTTPLKVPGRGR-----SA--------RAPGW-LSYSLWLGGQRHIIHMRV-K----
----K-FLVSKHLPVFT--YTDQRALHED---QPFV------------------------
----PDNCYYHGYVEGVFES-LVALTTCFG--GF----R--GVLQINHLTYEIEPRS-HS
-TTFEHLVYKRDSN-ET--QFPPMRCGLTEEE-I-----ARQ-LES-Q-KT-----YNTT
QK-------QSSYRGWWTHWRFLELVVVVDYNRFLHLLR-NTSVVQQEVLTVVHIVDSLY
GPFDVDVIL------IGIEIWNEGNPPL-S------NDIHLLAEEFAIWKKLHLDA-RLP
-SDSTHLFI----KESF-----GD-KLGV------AY--VKGICLPP-FNCGVDSF----
QGNQL-FSFALIVTHE-LGHNLGM-VH--DT-----------EWCVC--EQ-KWCIMFPS
QET---TTKFSNCSYAEYWD---NTIRQG--FCLRS--PP-N--PEKI---FR----LKF
CGNLMVEE--GEECDCGTI-H---QC-AN---DSCCLS-NCTLSP-GAACAFG------L
CCK--DCNFIPSGYLCRQQIS-ECDLPEWCTGTSHQCPEDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

NGIPCND---NAYC--
---YEKRC-NSHDT-------------QC--KEIFGK---DA---KSASQ-----SCYQK
INTQGNRFGHCGIT-------------------DIVYLKCETPDILCGRIQCENVGVIPN
LIQ--HS---TVHQIHF----N-GTTCWGT----------------DY-HLGMS------
-------I---PDIGQ

ENSGT00910000144019_0_Linker_9_10 (1097, 1139)

VKDGTVCGLK---------KICIH---KKCVHLSY-LPQ--D

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CQ
P-ETCNL-RGVC-----NN--KQH-CHCDHGWA-PP----------YCLM----------
-KG---YGGSNDSGPPYK---DIEEVEDV-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------MA---DSARDTASILPSPRKNQEL
RNEA------------------------SRGLQTWAPQMKG--WLPPL-PGP-SCARLAI
M--LV-------------LVLIFLPSMYCDLG-----------------------SVYHS
SYEIVIPQSLAVE

PF01562 // ENSGT00910000144019_0_Domain_1 (254, 429)

GR------E--------DPEEE-VSYTLPMQGQKQLLHLKV-K----
----R-DYFVHNFPVFS--YRN-GILGQA---VPFI------------------------
----SRDCHYEGYVEGVPGS-FVSVNICS---GL----R--GFLVKEEQSYGIEPMH-SS
-KRFEHVLYTMAHE-------ARVSCSVTSN-DSQVAPASQQ-QD----------SSKPR
SL-------QAP-SYLWSHTKYVEMFVVVNHQRFQMWGS-DANETVQRVMDIIALANSFT
RGINTEVVL------AGMEIWTEGDLAE-VP-----VDLRVALRNFNSWRQEKLVH-RVQ
-HDVAHMIV----GHRP-----KE-DMGQ------AF--LNGACSSD-FAAAVESF----
HHEDV-LLFAALMVHQ-LGHNLGM-QH--DH-----------SACVCKD--AHFCLMLEN
ITK---ESGFSNCSFDFFHQFLWE--HKG--ACLFN--KP-G--HKRRLRR------NGR
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ED--DEQCDCGS------DC-DI---HPCCDQ-TCRLKE-NALCNPS------P
CCN-VSCQYERIGRSCRPASG-TCDLPEFCLGNSGECPPDHYKLDGTPCQE---KNFC--
---VGGLC-RSFDY-------------QC--FDVFGY---PA---RSASE-----DCYRL
LNKKANRFGNCGMASS-----------------SNQYVQCADENILCGKVVCTNVQRLPN
IRS--LS---TMLQVPH----N-DDYCWTM----------------DMSGT---------
--------SDVPDDGWSYNGNVCGSD---------KICMN---FSCTASSV-LGY--SCN
EKELCNG-KGVC-----ND--LKH-CHCEIGFA-PP----------DCSS----------
-PG---SGGSVDSGPPGI---EPHPSPPDQGDGQN-------------------------
-------------------------T---SIMMLP--AL----LIVC-SISAVNTI----
-GIL---TV-----IT-LNLQIDLGCT-------------DI-LT---------------
-----ILILW---N-F----H--CG----------SV---G-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

PF01562 // ENSGT00910000144019_0_Domain_1 (307, 429)

TFLPQNFLVYI--YDETGYLHVE---PLSF------------------------
----KIFCHYQGYIANFPNS-AATLDICT---GL---R---GFLQFGNVSYGIEPLE-SS
-TKFEHII

ENSGT00910000144019_0_Linker_1_5 (429, 538)

YQVNNV-NA-D-IPMQVSN----Y-S----SIWQ-ED--H-P------SKVI
LS-------SQXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX

PF01421 // ENSGT00910000144019_0_Domain_5 (538, 760)

XLF
AQFKLTVVL------SSLELWSNNNQIS-TN-----VDADNLLQRFVAWKNSYLI---LQ
PYDIALLLT----YRKQ-----PK-YVGA------TF--PGTICNKT-YGADV-AV---Y
SDAVTLEGFSVTIAQI-LSLKIGL-KYD-S------------SKCICPG---ATCIMNHK
AMYFSGMKIFSNCSMDDYRYFASK--LAD--GCLWN--SP-N--IQSR-DQNQ-----PV
CGNGILEP--GEECDCGSE-E---EC-RF---KMGCDYNSGKLKG-SVKCGSR------P
PCT-STRELSKAGTPCRKSVDEECDFTEYCNGTSSSCVPDTYVLNGKLCGL-GT-AYC--
---YNGQC-QTTDS-------------QC--TKVFGK---GA---QGAPF-----ACFEE
INSPLGRLGNCGFKG-------------------SQPLPCGQKDVLCGKLACIWPHTSIY
KSD--V---EAAVYSYI----K-GHVCMSI----------------TT-ESSVM------
--------VDGRDYTYVADGTVCGPQ---------MYCVN--K-TCKKAQL-VEY--S

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CN
ANKKCKG-NGIC-----NN--LGN-CHCFPDYR-PP----------NCEF----------
-QI-GSPGGSIDDGNVQK---ADTV-----------------------------------
----------------------FT-R---SYKTH-------QNNWLILSFYIALPF----
--LIIF---------T-IMLIKRNEM------RKSC----N---RENAEYE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MKMLL
L--LHWL-----------GVFL--------S-CS------GH-----I-Q-DEHP-QYHS
PLDVVIPVRITGTTR----

PF01562 // ENSGT00910000144019_0_Domain_1 (260, 429)

-GM--------KPPGW-LSYILPFGGQKHIIHIKV-K----
----K-LLFSKHLPVFT--YTDQGAILED---QPFV------------------------
----QNNCYYHGYVEGDPES-LVSLSTCFG--GF----Q--GILQINDFAYEIKPLA-FS
-TTFEHLVYKMDSE-EK--QFSTMRSGFMQNE-I-----TCR-MEF-E-EI-----DNST
QK-------QSSYVGWWIHFRIVEIVVVIDNYLYIRYEK-NDSKLLEDLYVIVNIVDSIL
DVIGVKVLL------FGLEIWTNKNLIV-VD------DVRKSVHLYCKWKSENITP-RMQ
-HDTSHLFT----TLGL-----RG-LSGI------GA--FRGMCTPH-RSCAIVTF----
MNKTL-GTFSIAVAHH-LGHNLGM-NH--DE-----------DTCRC--SQ-PRCIMHEG
NPP---ITKFSNCSYGDFWE---YTVERT--KCLLE--TV-H--TKDI---FN----VKR
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EE--GEECDCGPL-K---HC-AK---DPCCLS-NCSLTD-GSTCAFG------L
CCK--DCKFLPSGKVCRKEIN-ECDLPEWCSGTSHKCPDDFYVEDGIPCKE---RGYC--
---YEKNC-HDRNE-------------QC--RRIFGA---GA---NTASE-----TCYKE
LNTLGDRVGHCGIK-------------------NATYIKCNISDVQCGRIQCENVTEIPN
LSD--HT---TVHWARF----N-DIMCWST----------------DY-HLGMK------
-------G---PDIGEVKDGTECGID---------HICIH---RHCVHITL-LNS--NCS
PA-FCNK-RGIC-----NN--KHH-CHCNYLWD-PP----------NCLI----------
-KG---YGGSVDSGPPPK---RKKKKKF--------------------------------
---------------------------------------------CYLCILLLI------
-VLFILLC---------C-LYR--------LCKKS-----KP-IKKQQDVQTPSA--KEE
EKIQRRPH-----E-----LPPQ----------SQPW--VMPSQSQPPVTPSQSHP----
-------QVMP-SQS-----------QPPVTPSQSQPR-V------MPSQSQPPV-----
---------TPSQSHPRV-----MPSQSQPPVTPSQSQ--------------------PR
VMPSQSQPPVMPSQRQPQLMPSQSQPRVTPSQSQSPVTPSQRQPQLTPSQSQPPVTPSQS
QPRVTPSQSKPHVTPYRSQSGKQKQSVP--IPKTVSRKGTLKK--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

PF01562 // ENSGT00910000144019_0_Domain_1 (285, 429)

GRPRVLRLQP-R----
----R-GLVSRPFTLVT--YGRDGTRREE---HPFV------------------------
----RDNCFYQGDVLGSPES-MVALSTCGK--GL----H--GVLWVENDTYRIEPVP-ND
-PAFRHIL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YRMEEA--N--SPEGQGCGLTPEV-L-----QQQ-KAV-L-PWL--KAPKTE
GG-------NEKLEGWWTHI

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 756)

RYVKMVVVVDHVRFVKSGK-NKTEVLKDVMHVINVADAMY
KPLSVRLFL------IGLEIWTESNFIN-IT-----NSIPSVLGQFNTWRKENLVG-RLH
-HDVAHLFA----FQRF-----GS-SLGL------AY--IGTVCDSH-WASAVVSF----
TEKKL-SGVFVTFAHE-LGHNLGM-VH--DK-----------PECYCKR---KTCVMYEN
N-A--KTDSFSDCSYKDYFDLVVN--R-A--PCLRQ--PP-E--PGSF-YTGK----QEY
CGNKVVES--GEQCDCGSP-A---NC-RR---DPCCHT-NCTFTA-GSVCASG------K
CCK--NCQFLPAGTLCRASTG-GCDLPEYCNGISPQCPLDVYKQDGTPCQD--G-IYC--
---YKGKG-SSHRE-------------QC--QNIFGK---RA---TVAPL-----DCFKA
VNTQGDRFGNCGIR-D-----------------NVHFTKCSTQNILCGRIQCENIGKLPF
LEN--HV---TVVQTPV----Q-DKKCWGL----------------DY-HVG--------
--------IPRADVGAVEDGTPCGND---------MLCIN---RTCMSVSV-LNY--DCN
L-TKCHD-RGVC-----NN--RKN-CHCDYGWA-PP----------YCEL----------
-EG---FGGSIDSGPPPA---RKM------------------------------------
----------------------------------S--QR----AKVRL---ILLG-----
--FFVMCI------IG-VALSIYYRREI-----ARW---LTN-KKARFQ---------TE
NEKKEKKGKKRKKKKFPKK-----------------NPPKVVS-QNPPKVVSQNPPKVVT
Q---NPPKVVSQNPP-----------KMVSQN----PP-K------VVSQNPPKVVSQNP
PKVRRGRPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP-PPPPPPPPPPPPPPPPPPP
PPPP-PPPPPPPP---PPPPPPPP---PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
PPPRA--------------PGRRRK--------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--VLFLL-------SGLGGLW--M--------------------------DSNFDS--L
PVQITVPE

PF01562 // ENSGT00910000144019_0_Domain_1 (249, 429)

KIRSIIK----EE---I-------ESQ-VSYKIVIEGKPYTVNLMQ-K----
------NFLSHNFRVYS--YNGTGIMKPL---DQDF------------------------
----QNFCHYQGYIEGYPKS-VAMVSTCT---GLR------GLLQFENVSYGIEPLE-SS
-VGFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQVKHK-KA-D-VSLYNE----KD-I-------E-SRD-L-S------FKLQ
SI-------EPQ----KDFA

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 720)

KYIEMHVVVEKQLYNHMGS-GTTVVTQKIFQLIGLTNAIF
VSLNITVIL------SSLELWIDENKIA-TT-----GDAKELLHTFLRWKRSYLV---LR
PHDVAFLLV----YREK-----SN-YVGA------TF--QGKICDAN-YAGGV-LL---H
PRTISLESLAVILAQL-LSLSMGI-PYD-DI-----------NQCRCSA---AVCIMNPE
A-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MTVGEA-L---VHFRVTP
L--LLWF-----------GVCL--------F-IS------GH-----C-Q-ARPS-QHFS
SPELVIPLKVTGWGR-----NA--------KV

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

PGW-LSYSLRFGGQRHITHMKV-K----
----K-LLISRPLPVFT--YTDQRSLHQD---QPYL------------------------
----PDDCYYHGYVEGVPKS-LVALSTCSG--GF----R--GVLQINDLAYEIEPVR-SS
-ATFEHWV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YRIDSD-DT--QFPRKRCGLTEEE-I-----ARQ-LEL----------HNFT
LK-------QSSYTGWWTHLL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 756)

FLELVVVVDNLRFVHSGS-NVSVVQIEIATVVNVINSLY
HPLEVDVTL------TGLEIWTEGNQIA-T------ENMEKMLEDFALWKFFNLDN-RLP
-HDAAHLFI----KKSF-----GR-QLGL------AY--VGGVCQNP-LNCGIVVF----
EDDSL-FDIGLIVTHE-LGHNLGM-LH--DT-----------EFCVC--EF-EFCIMYPA
KAV---TSKFSNCSYGEFWN---NVMRNG--FCLIS--PP-N--PANI---FR----IKY
CGNLVVEE--GEECDCGTV-Q---QC-KH---DHCCLL-DCTLKP-GAACAFG------S
CCE--NCKVRSAGTLCRKQIN-ACDLPEWCNGASHQCPEDVYVQDGIPCSD---SAYC--
---YKKNC-ANHDE-------------QC--REIFGK---DA---RSASR-----SCYKE
INTQGNRFGHCGIR-------------------DIEYIKCEVPDILCGRVQCENVEVIPN
LME--HS---TVHQFQV----N-DTTCWGT----------------DY-HIGMS------
-------I---PDVGQVKDGTICGQK---------KICVH---SRCVSMVP-EPQ--ACQ
P-ETCHM-KGVC-----NS--KQE-CHCNPGWA-PP----------YCKD----------
-EG---SGGSNSSGPPGN---PQGDEEEEDLVLERL------------------------
-------------------------S---CLNVLR--DPLVPGVPGGHHT-----L----
-TCLGIWS---------SKGC----------HAS--T-CSGI-R----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------SA

PF01421 // ENSGT00910000144019_0_Domain_5 (674, 760)

AHQ-LGHAIGF-AH--DDDFPRPNGQNCDCDCDSKP---GHCIMYS-
AVA--ECYKLSNCSKNAYRNLLAQ--KGK--DCFMN--LP-K---DNN-F-------IKI
CGNGVVEG--DEMCDCGTD-K---VC-QR---SGCCLK-DCTLKL-NTSCYYG------S
CCK--KCKVSIEGTLCREAVN-ECDLPEYCSGDSADCPADVYKMDGIPCGT--D-HHC--
---YFGAC-LDLQH-------------HC--TVLFGQ---GA---KPAPL-----NCYKT
LNMRGDRTGNCGKE-------------------GNKYKKCREEDVFCGRIQCTNVKKIPR
TST--RQ---GVIQTPV----D-DILCLGT----------------EF-HEE--------
--------GDVYDLGAIRDGSKCGPD---------MMCIN---RTCVEVMS-LNY--DCS
F-SKCSN-RGVC-----NS--NQN-CHCEYGWA-PP----------SCSG----------
-RG---FGGSIDSGPPPE---NAN------------------------------------
----------------------------------I--LA----SFCI-------IP----
--LSELLF------MF--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------ET-L---VHVRLIL
L--LLWL-----------RVFL--------F-LS------AL-----S-Q-VGLS-S

PF01562 // ENSGT00910000144019_0_Domain_1 (238, 419)

HHG
PPEVVIPLRFARSAA-----GS--------PVFRW-LSYRMNFGGQRHIVHMKV-N----
----K-HFLYRHLSVFT--YTDQGTLLED---QPFV------------------------
----QNDCYYHGYVE-DSES-LVSLNTCVG--GF----Q--GIIQTMDTIYEITPKR-L-
-TIFEHLVHRIDSE-ET--QSPPMRCGLTDEE-I-----ARQ-LKL-Q-GS-----DTFT
LM-------RTPYEGWWLHKRYLEIAVVVDNNRFIHRDS-NVSDVQKEAYEVIHHTNNFF
KTVDIEVTL------MGIEIWTEGNLIL-LD------DIYRGLRRFCDWKRQGFND-RLP
-HDAAHIFS----GKGF-----GI-VGGL------AY--VGTVCNSR-HNCGIESF----
QTEDL-VSFANTVTHE-VGHTVGM-KH--DD-----------GTCTC--GR-SRCIMNAG
KGD---THRFSNCSYTWYSEL---M-LRT--KCMYI--PP-S--PERI---FT----MTR
CGNSVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

EE--GEECDCGSL-----TC-IE---DHCCQS-NCTLIP-EADCAFG------L
CCQ--DCKFMPSGTMCRKKEN-ECDLPEWCNGTSHQCPEDVYMQDGFLCKS---GDYC--
---YEKRC-NNRDE-------------QC--RKIFGK---EA---KSANQ-----SCYMR
INTRGDRFGHCGLK-------------------NTAFVRCNTSDSLCGRVQCENVTKIPF
LEE--HS---TVHWTHF----N-DVTCWGT----------------DY-HYGMT------
-------I---PDIGEVKDGTECGVD---------HICIQ---KKCMPMSH-LDR--DCS
PE-TCNM-KGVC-----NN--RH--HHCNYPWD-PP----------DCLK----------
-NG---TGGSIDSGPP--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------TGP--FST-ASLW---SC-LWLCLQL
C--SL-------------LGIFLPGTYSFIQK-----------------------SVYF

PF01562 // ENSGT00910000144019_0_Domain_1 (240, 429)

S
VYEIIIPRRLANWKR------E--------NHPEK-IQYSFFMKGRWHVMSLKQ-K----
----E-GLFVQNFPVYT--YSN-GIPSLD---ISSV------------------------
----QGNCYYDGYFIGDRGS-FASISTCS---GL----K--GILIIEMNAFSILPVK-SS
-RKFEHAL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YRLSRV-------SGDTCGVKNR-ESQKFWAKPE-SF----------SLMEF
SS-------AHF-THAWSYP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYLEIFIVVDNIRFQMWDK-NVTTTTQTLIDVLALVNHHM
KQINLEVVL------AGVEIWSERNLVH-IS-----QDLQETLYDFNQWQASELPK-RAT
-YSVAHLIT----GQDV-----GS-HQGH------AF--VGTVCASR-NLAGVEVF----
HQEDI-PRFAALLAHE-LGHNLGM-KH--DH-----------PDCTCPD--SHFCSMHEL
ITL---KGTFSNCSLKDFYKMLGS--SQG--TCLYN--KP-K--SKSP-FG------RQY
CGNKIVED--GEQCDCGSA-Q---EC-LK---DQCCLP-SCQLRE-GSECAFG------P
CCQ--NCRFAEATTPCRPKVD-ECDLPEYCNGTSRWCQPDTYKQDGFPCRD---QSYC--
---YQGRC-GSLEK-------------QC--IELFGK---DS---RPASN-----RCYH-
MNTQGNRYGNCGIKWHGP---------------VQVFSQCQPQDIMCGKLYCENIQTLPH
IKN--HY---AFFQLLM----E-DTWCWGV----------------DLYNAL--------
---------DMPNGGLVQEGTSCGHK---------KICIN---QSCLDIEV-VSR--DNC
SLDKCHG-KGIC-----NN--LKN-CHCNYGYE-PP----------TCQF----------
-HG---QGGSLDSGPSPR---FKIVHHKLASL----------------------------
--------------------------------------------------IWFIMV----
-FAWLLMPI-----VF-VGVCSYWKTDK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--VLFLL-------GGLGGLR--M--------------------------DSNFGN--L
PVQITVPEK

PF01562 // ENSGT00910000144019_0_Domain_1 (250, 429)

IRSITK----EG---I-------ESQ-VSYKIVIEGKPYTVNLMQ-K----
------NFLPYNFRVYS--YNRTGIMKPL---DQDL------------------------
----QNFCYYQGYIEGYPKS-VVMVSTCT---GLR------GLLQFENVSYGIEPLE-SS
-VAFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQVKHK-KA-D-VSLYTV----KD-I-------E-SRD-L-P------YKIQ
SI-------EPQ----PDFA

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYIEMHVVVEKQLYNHMGS-DTTAVTHKVFQVIGLMNAIF
VSFNLTIIL------SSLELWIDENKIA-TT-----GDANELLQTFLKWKKSYLV---LR
PHDVAFLLV----YREK-----SN-YVGA------TL--QGKMCDAD-HAGGV-VL---H
PRTISLESLAVILAQL-LSLSMGI-TYD-DI-----------HKCQCSG---GVCIMNPE
AIHFSGVKTFSNCSFEDFAHFISK--QKS--QCLHN--QP-R--LDPL-YK----QQ-PV
CGNTILEA--GEECDCGTE-Q---NC-TLIG-ATCCDSVTCRLKA-GLNCAEG------P
CCK--NCLFLSKGRVCRPAFD-ECDLPEYCNGSSASCPENHYVQTGHPCGM-NQ-WIC--
---INGVX-XXXXX-------------XX--XXXXXX---XV---EFGPA-----ECYSH
LNSKTDVSGNCGEVDS------------------R-YTQCGA------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------TSSF----DVSWDMVAMGEA-V---MHIRITH
L--HLWL-----------EMLI--------L-LS------TW-----P-L-TEQA-QHTS
LPEVVIPLRVTGN-R-----TM--------WAM

PF01562 // ENSGT00910000144019_0_Domain_1 (274, 417)

GW-LTYSLHFGGQRHFIYMKA-K----
----K-AFISRQLSVFT--YTDQGALHKD---QPFV------------------------
----QKDCYYHGYMDGDPDS-MVALTTCFG--GI----Q--GILQINGTVYEIKPK

ENSGT00910000144019_0_Linker_1_5 (417, 502)

N-LS
-STFEHLVHKIHSE-ET--QLLPMRCALTEEE-L-----ARQ-MKL-H-RN-----DNPT
LM-------QSGYEGWWTHKS

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 747)

FLELALVVDHERIRYLNG-NQSRVLQEILIIVGVINGIY
LTLDVEVVL------LGVEMWNEGNPIT-VN------NIYDLLTDFCFWKVISLNN-RIQ
-NDIAHLFV----LYDF-----QQ-YLGL------AF--VGTVCMPW-DNCGVDRL----
IGDNL-FHFGHITAHE-MGHNLGM-LH--DE-----------GSCTC--GM-ERCLMAPT
DSG---TLNFSNCSYADFWK---VY-ATA--NCMRK--GK-K--PISI---YK----LKS
CGNGVVDD--GEQCDCGSW-K---KC-TE---DPCCMR-GCTLKH-GAACAFG------L
CCK--DCQIMPSGTVCRAKEN-ECDLPEWCDGHSHECPKDVYLLDGSSCKD---GGHC--
---YEKRC-NNRDV-------------QC--QQIFGK---EA---RSAAQ-----RCYRE
INSQGDRFGNCGLF-------------------RSTYLRCKDSDILCGRVQCENVKALPS
LKD--HS---SVHWTHL----N-GVTCWGT----------------DY-HFGMT------
-------I---PDIGHVKDGTDCGPE---------HVCIN---RKCVNKSI-WVS--HCS
PE-TCNM-QGVC-----NN--LDH-CHCNYGWK-PP----------FCLA----------
-HG---FGGSVDSGP---------------------------------------------
-------------------------------------------RNNWVSIIPV--L----
-V--IFPF---------F--VF--------ICLRN----KY-------------------
--VMSH-K-----REEPSVSSSE----------------E--------EEESSDVS----
----------TYSKS-----------S---------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
R--LWLLL-------ARLCGLL--AS--------------------RP-----GFQN--S

PF01562 // ENSGT00910000144019_0_Domain_1 (241, 429)

LLQIVIPEKIQTNTS--DSSET--E-------YEQ-ISYIIPIDEKPYTVHLKQ-R----
------YFLADNFMIYL--YDQ-GSMNAR---SSDI------------------------
----QTQCYYQGNIEGYPVS-MVTLSTCS---GL---R---GILQFENVSYAIEPLE-SA
-VEFQHVLYKLENE-DN-D-IAIFSEN----N-R----SLKE-H-P-M-D------DNIS
RS-----EQSEPA-VPDLFPLYLEMHIVVDKALYDYWGS-DSMIVTNKVIEIVGLANSMF
AQFKVTIVL------SSLEVWSDENKIS-TV-----GEADELLKRFLEWKQSYLN---LR
PHDIAYLLI----YRDY-----PD-YVGA------TF--PRKMCITR-YSAGV-AL---Y
PKEITLEAFSVIVTQM-LALSLGI-SYD-DP-----------KKCRCSE---SICIMNPE
ALQSNGVKTFSSCSLRSFQNFISN--VGA--KCLQN--KP-Q--MQK---KSP--K--PV
CGNGRLEG--SEICDCGTE-A---QC-GP---ASCCDFRTCVLKD-GAQCYRG------S
CCR--DCQILQSGVECRPKAHPECDIAENCNGSSPECGPDITLF

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1096)

NGLPCKN-SK-FIC--
---YDGDC-HDLDA-------------RC--ESVFGK---GS---RNAPF-----ACYEE
IQSQADRFGNCGRDRN------------------NKYVFCGWRNLICGRLVCTYPTRKPF
HQE--N---GDVIYAFV----R-DSVCVTV----------------DY-KLPR-------
---------TVPDPLAVKNGSQCDVG---------RICVN--R-ECVESRK-IKATALVC
SEHICSG-HGVC-----DS--RQK-CICSPGYN-PP----------SCQT----------
-RS---KGFPIFPKED-----MD-------------------------------------
--------------------SIMK-R--AFG--K-------TENTWLLGFSLVLPI----
--LIVT---------TIVV-LARKHL------KKWF----I--KEEEFPSSES-------
-KSEGSTQT-------YASQSISEGSTQT-----YA------S---RTRSESSGQADTSK
S---------KSEDSTQAY--------------------------TSRSKSQEST-----
-------QTQSS------------------------RN----------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSVRT-F---LSQGPLL
P--TLVLV-VLL--VDSLGKDL-------NL-PP------GW-----D-F---------D
SYEITIPKKLSFRGG-----VQ--------GV

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

AKH-VSYLLQVKGKSHVLHLWP-K----
----R-FLLPRNLQVFS--FTELGRLWED---HPYI------------------------
----PSNCNYMGLVEGNQDS-EATLSTCMG--VL----R--GILKIDASHYQIEPLK-AS
-SSFEHVIYLLKKE-E---EFPHQICGLTDDE-T-----LKQ-MAQ-H-KNV--A-----
-R-------ISDFSQSYMHQKYLELALVFDHSRYIFLNS-NLSRVINDAILLSSIMDTYF
QDVRMRIHL------TGVEVWTDEDKIR-LT----YPKLEQVLGQFMVYRTSVLNA-RFP
-VDWIHLYL----KRNY-----SD-SLAL------YL---GNVCTKF-HAGSTSVF----
PDVNV-LGPATWSTHA-LGHGVGM-RH--DE-----------EYCQCKGR--HSCIMGSG
------QYGFSNCSYAHFFAHVY--SG-A--KCLTN--IP-E--LSY---V------VKR
CGNKIV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EE--DEECDCGSI-E---DC-KN---DHCCQP-DCKFKH-GAKCSIG------L
CCH--KCQFRPSGYKCRLEEN-ECDLAEYCNGTSALCPSDTYKQDGTPCKD--E-AHC--
---FNKAC-QSRFM-------------QC--QKIFGP---DA---TEAPL-----QCYVA
INVIGDQYGNCGIS-G-----------------VREYRKCNRRNALCGRIQCINVNTIPD
MPD--HT---ILISTHL--HDE-NLKCWGI----------------GY-HPAMV------
-------PMGLPDLGVVSDGTSCGRN---------NVCFN---RNCVNSSV-LKF--DCF
P-EKCNH-RGVC-----NN--NKN-CHCMYGWS-PP----------LCEE----------
-LG---YGGSIDSGPPGP---LKE------------------------------------
--------------------------------------G----VPTSVQ-VVSLMF----
-VRLIFLIIS----V--IVV--FFKKIIG-NFKTQR---ESN--P--------TT-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------LKSF--LASCSWLL--MGV------SFARAGF
L--LALEL--T---LL-------YLASCLQH-RP-----

PF01562 // ENSGT00910000144019_0_Domain_1 (220, 428)

-GW-----R-F---------S
SFEVVIPHQLSSRKA-----LRGSSG-TFAEVPGR-LSYSLRFGGKRYVVHMRV-K----
----K-FLLPRHLPVLV--DNKHGAPQEE---YPYV------------------------
----PNDCYYHGYLEGIPAS-MAVLNTCQG--GL----R--GTLHLDDFTYEIEPLH-SS
-TQFEHV

ENSGT00910000144019_0_Linker_1_5 (428, 501)

LSQLVPE-EGEAGQSLFRCTLTNEE-M-----NER-FSN-S-------DIDIR
PR-------AGPYSHWWPHV

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 755)

RYLKIAICVSSSRVETHNG-NLTIHVDQMVTLTHIVDSIY
KQFRVFTIL------VFLYLWQYSDKVP-LI-----GSSSEIAEHYGLWKSLVISN-NFP
-HDTSALVT----GNKA-----GE-SGYA------AF--PNSICSGN-WAVILLWL----
QDDRV-FYYSVILAHY-IGHNFGL-PH--DQ-----------IYCHCIRR--SHCLMEDH
P-L--FSDSLSNCSYGRFFNLVNY--W-D--QCLNR--LP-N--AYDN-YAYS----FHL
CGNKKIDY--TEQCDCGSI-K---EC-LA---DPCCDL-RCERTP-GSSCGYG------P
CCE--DCHFSPMGLACRRAVS-TCDLPEFCNGTIHLCPLDTYVQDGTPCTS--N-AIC--
---FKGNC-TDRHL-------------QC--RQVFGH---NG--VINAND-----ACYEQ
LNIKGDRFGNCGMEPERKNNSNGMEVKEEGTQIKYITVPCRQSAVLCGRLQCEGLKIVPK
LDE--HI---TVHQMSVRKNKR-EIFCFGI----------------EH-HFG--------
--------TGWLDFGMVWDGSKCSKT---------TMCLN---HMCVPIAQ-LHF--DCT
P-AKCNY-RGVC-----NN--NRN-CHCQFGWA-PP----------FCTL----------
-LG---YGGSLDSGPTDN---DEV------------------------------------
----------------------------------D--YV----LFAI-----LIFVL---
-VRMILFMVS----FS-TAVIMQPEMPP-----------------KKNE----------H
S-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--KFCL-----------WTMF--------F-FS------AW-----S-P-IGHA-KYSS
LPEVVTPLRVTVTRG-----NN--------

PF01562 // ENSGT00910000144019_0_Domain_1 (271, 429)

TSPGW-LSYSLNIGGQRHIITMKP-K----
----K-NLMSRNLILLT--YTQQGDLLEQ---RPFV------------------------
----PNDCYYHGYVDEDPES-LVILNTCFG--SL----Q--GTLEINGTTYEIMPKS-ST
-STFEHLAYKMDNG-DS--EPSPMRCGLSEEE-I-----AQQ-RKL-R-ER-----NAPT
LL-------QIPHENWWTHHRFIEYFVVIDHKQYVHRNN-NITTCIQDMLQIVNGVNGYY
LQIDTDVVL------TALEIWNEKNYIN-VE-----LSIFKVLGDFCTWKQNMFGN-RIR
-HDIIHLLV----RQGY-----GL-YLGL------AY--LADVCTP--YNCGVSSF----
LSDVM-SDMAHIVAHE-MGHNLGM-KH--DG-----------IGCTC--GL-KDCLMAPY
KTN---SPKFSNCSYEEMYS----VVTKR--SCLYD--IP-E--ALVT----N----LTV
CGNKVVEE--GEECDCGST-E---SC-LQ---DPCCSS-DCVLKP-GAQCAFG------L
CCQ--DCQFLKTGTVCREEKN-ECDLPEWCNGTSAECPGDVYKA

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1092)

DGIPCSG---EGYC--
---YKMEC-HQRDE-------------QC--RKIFGN---GS---RSADE-----ICYME
MNRRGDRFGNCGND-------------------SSKYKICELADVLCGRIQCENVIQLPQ
RRN--HE---TVHYTHF----S-NVTCWTM----------------DY-HFGIT------
-------I---DDIGAVSDGTACAPY---------HICVD---RKCVSKSD-LVS--NCT
TK-LCHM-QGVC-----NN--KNH-CHCTNTWE-PP----------DCQL----------
-RG---HGGSLDSGPPPL---HVPNS----------------------------------
-------------------------------------SW---A-------FYFISF----
-FTI---L---------LVITI-------S--LVG--ITKR--VKMN-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--VLFLL-------SGLGGLW--M--------------------------DSNFDS--L
PVQITVPE

PF01562 // ENSGT00910000144019_0_Domain_1 (249, 429)

KIRSIIK----EE---I-------ESQ-VSYKIVIEGKPYTANLMQ-K----
------NFLSHNFRVYS--YNGTGIMKPL---DQDF------------------------
----QNFCHYQGYIEGYPKS-VAMVSTCT---GLR------GLLQFENVSYGIEPLE-SS
-VGFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 513)

YQVKHK-KA-D-VSLYNE----KD-I-------E-SRD-L-S------FKLQ
SI-------E----------------------

PF01421 // ENSGT00910000144019_0_Domain_5 (513, 760)

-YNHMGS-GTTVVTQKIFQLIGLTNAIF
VSLNITVIL------SSLELWIDENKIA-TT-----GDAKELLHTFLRWKRSYLV---LR
PHDVAFLLV----YREK-----SN-YVGA------TF--QGKMCDAN-YAGGV-LL---H
PRTISLESLAVILAQL-LSLSMGI-PYD-DI-----------NQCQCSA---AVCIMNPE
AIHFSGVKIFSNCSIEDFAHFISK--QKS--QCLHN--QP-R--LDPF-FK----QQ-AV
CGNAKLEA--GEECDCGTQ-Q---NC-FLLG-AKCCDTATCRFKA-GSNCAEG------P
CCE--NCLFMSQERVCRPSFD-ECDLPEYCNGTSASCPENHFIQTGHPCGP-NQ-WVC--
---IDGVC-MNGDK-------------QC--MDTFGG---EA---EFGPT-----ECYSY
LNSKTDVSGNCGIGDS------------------G-YTQCEA------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGRAWT-QAH-LRGDLWL
P--LLWLF---------------L

PF01562 // ENSGT00910000144019_0_Domain_1 (205, 428)

SPTCCSHDPP------GW-----R-F---------T
SSEIVIPRKVSHRVS-----GI--------ERQGQ-LSYKIRFSGQRHVVHLRV-K----
----K-NLLPRHFPVIT--DNDQGAMQEN---YPYI------------------------
----PRDCYYFSYLEGVPGS-MGTLDTCHG--GL----R--GMLQLDDFTYEIKPLE-AS
-SKFEHLISQLVTQ-KT--AAEDEKCEAEEK-------DTNQEYEE--------AMISEM
PR-------AGTVYLWWPHRKALKVHYTVSNSLVVQN-N-NMTRITENVVILNNIMHSIY
YQGQLQVLI------RVLCIWDGADKMN---L-YEFNSASKAVTDFGLWKYWGWYN-EIA
-HDTSLLIT----GHKI-----AGATYSS------S---FNGVCNPN-WGASYVFA----
ARYHL-FLTATIGAHA-IGHVLGC-HH--DV-----------PGCQCFRR--KHCLMSPN
PGL---LDMMSNCTFERIHIR-LH--TWD--SCLSV--PY-V--PYNN-FPYI----ARR
CGDKKLDP-

PF00200 // ENSGT00910000144019_0_Domain_7 (790, 882)

-NEECDCGTL-K---DC-SV---DRCCNS-NCGLSL-GSDCDFG------G
CCR--NCKYAYPGYICRDTLG-ICDLPEYCDGKTHECPDDTYIQDGTPCSP---SAVC--
---MRGNC-SDRDL-------------QC--QALFGF---KI---KAAAS-----SCYEV
LNLRGDRFGNCGVRVTKG---------------GGKPVPCERDDVKCGMLHCSSVKEIPG
GGE--HTTFHQIIVHDV----T-PQTCFGY----------------DA-HFG--------
--------TDVPEMGLVVDGATCGPG---------AYCKD---QNCTFFQD-LDF--DCD
VK-KCNY-RGVC-----NN--KKN-CHCQRGWK-PP----------KCTE----------
-RG---PGGSVDSGPPPD---TELGIRASL------------------------------
-------------------------------------------RLSLNA-ALALLL----
-LRLCLLSLS----AF-IGATF------Y----VKD---KLE-ERDESVE----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------QAPSLMGPAWA-QAH-LTGNLWL
P--LLWLL---------------LSPGCCSRALP------GW-----R-F---------T
SS

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 428)

EVVIPRKVSHRVG-----GM--------ERQGH-LSYKIHFRGQRHVVHMKV-K----
----K-NLLPRHFPVIT--DNDQGAMQED---YPFV------------------------
----PRDCYYYSYLEGVPGS-MGTLDTCNG--GL----R--GMLQVDDFTYEIKPLE-AS
-STFEHV

ENSGT00910000144019_0_Linker_1_5 (428, 502)

VSLLVTE-GR--SSEAQKCKIGEQ-------DTDQAYEE--------AMLAGT
PR-------AGPVYLWQSHRK

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 741)

FLKIHYTISHSLYLMR-P-NITQAIEGVVMINSILHTIY
QQSLINVYI------RLLCIWNDRDHVE---I-TKKKSAYSAVEDFGLWKYYGFFY-KIE
-HDTSLLLT----GHKI-----VGSIYFA------H---HGGTCNPN-WGAMFVYV----
ANYHI-FLAGGISAHT-LGHSLNL-VH--DV-----------FGCKCFRR--SHCVMTEQ
PGL---MDMLSNCSYDSLHRR-VS--GWD--PCMSI--PN-V--PYTN-FPYV----APR
CGDKIRNQ--LEECDCGSL-K---DC-ND---NKCCET-NCAFSL-GSDCSEG------S
CCV--NCKYAQPGLLCRDILG-ICDLPEYCDGTSHNCPNDVYTQDGTPCST---LAVC--
---VRGNC-TDRDM-------------QC--QSLFGY---GI---KDAAP-----ACYEK
LNVLGDRFGNCGVRVVRG---------------GGKPVRCEEDDVLCGMLHCRDVEEIPG
GGD--HVTFRHIIVTGI----N-QEKCFGY----------------DA-HHG--------
--------TEIPEMGLVVDGATCGPG---------KYCLN---QNCTFYQD-MGF--DCD
VS-TCNF-RGVC-----NS--KKH-CHCMRGWK-PP----------TCEE----------
-KG---AGGSIDSGPPPD---REYVLRGKV------------------------------
-------------------------------------------TVSVNR-ALGLIV----
-IRTLLFLTG----LI-IGLFF------Q-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MTGAKV-V---VHKRNMF
L--KFCL-----------WTMF--------F-FS------AY-----S-P-IGHA-KYSS
LPEVVTPLRVTVTRG-----NN-------

PF01562 // ENSGT00910000144019_0_Domain_1 (270, 429)

-SSPGW-LSYSLSIGGQRHIITMKP-K----
----E-NLISRNFLLFT--YSDQGDLLEE---HPFV------------------------
----QNDCYYHGYVDEDPES-LVIVNTCFG--SL----Q--GTLEINGTIYEIMPRS-KT
-STFEHLAYKMDSG-ES--EPSPMRCGLSEEE-I-----AQQ-MNL-Q-ES-----NAST
LL-------QIPYENWWTHHRFIDYFVVIDHNCYVHRNN-NTTTCIQDMLQVVNGINGYF
LQIQTDVVL------TKVEVWSQNNLIN-VE-----EEMSAALDAFCSWKKNAIGN-RVR
-HDIIHLFV----RHNY-----VK-FLGM------AK--LGQVCLT--LNCAVNSF----
LTDSL-SYLAFIVAHE-MGHNLGM-KH--DG-----------SACTC--GL-HTCIMYPY
AYI---SPKFSNCSYEEMFS----VVNRR--SCLYN--IP-D--ALKT-ITLV----PTM
CGNNLV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EE--GEQCDCGNS-E---SC-LQ---DPCCSS-DCVLKP-GAKCAFG------L
CCK--DCQFLQTGTVCRQEKN-ECDLPEWCNGTSGECPGDVYKADGIRCSR---GGYC--
---YKMEC-QRHDR-------------QC--REIFGK---RS---RSADE-----ICYME
MNRRGDRFGNCGND-------------------SSMYKRCELTDVLCGRIQCENVIKLPQ
RRN--HE---TVHYTHF----S-NNTCWTM----------------DY-HFGIT------
-------I---DDVGAVSDGTPCAPD---------HICLD---RKCVSKSV-LVS--NCT
PH-LCHM-QGVC-----NN--KHH-CHCTNTWE-PP----------DCQL----------
-HG---HGGSIDSGPPPV---PLSPS----------------------------------
-------------------------------------NW---S-------MYFLAF----
-IIM---Y---------VLGFI-------A--LYG--IREL--RKKL-LKES--------
---------------------------------------------V-PESD-SGDK----
-------N---LTRK-----------QQ-DL-----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------IFPLPRPPGST-S---HCISKTL
LCYILWKC----YSPACLAESI--------P-LP------SW-----M------------
APAWALPKTWPPRSG-----DS--------LL

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

QGW-FSYKLHFGGQRHVVHIKV-K----
----K-NFLSKNFPVFT--YADKGVLLQD---QPFV------------------------
----QDDCYYSGYVEGDPES-LVSLSNCFG--GF----Q--GMLQTNDVVYEIEPKR-FS
-TAFEHLI

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKLDNE-EM--NFSYFQCGLTDEK-I-----AGQ-LKI-Q-ES-----INST
LM-------QSDYTGWWTHHY

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

FVEVAVVVDHSRYLHHSS-NASLVQKEVFLVLNGVSDLM
KALGLEVFF------KGMEIWTKQSLIS-VV------DITHTLMNFCRWKQKGFHN-RVP
-HDVAHFFV----KKNF-----GD-EFGL------AY--DAQACAVR-YSCSVETF----
HDEGT-FFYSYVVAHD-VGHNLGM-HH--D----------T-ETCQC--GA-PKCIMFEA
IEA---TTKFSNCSYADYWN---VG-RRR--SCLYN--TP-N--PHTL---VT----EIR
CGNSVVDE--GEECDCGSL-K---TC-NT---DPCCQL-NCTVTA-GINCAFG------L
CCD--NCMFRKPGTLCRKEEN-ECDLPEWCNGTSNQCPDDVYVQDGASCTG---GGYC--
---YGKRC-NERDE-------------HC--RQIFGK---EA---KDADM-----SCYTA
VNTRGDRFGNCGIT-------------------ETSYIRCSMADSLCGRIQCENVKEIPV
MSD--HI---TLHWTKF----E-NNTCWGT----------------DY-HLGIR------
-------I---ADIGAVKDGTKCGPE---------NICIR---RRCVSYST-VPR--NCS
PQ-LCSL-RGVC-----NN--RQH-CHCNYGWG-PP----------VCQE----------
-KG---RGGSVDSGPAPE---RQTEERM--------------------------------
-------------------------------------------DRKNLLTYFLIPF----
-LFL--LL---------CLLLWLW------LFTRPK---KKD-EKEQAVP-PK-----S-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAVGDT-L---LHLRVVL
L--LLWL-----------EV

PF01562 // ENSGT00910000144019_0_Domain_1 (201, 429)

SL--------S-TC------GH-----S-Q-ARPS-QHFT
SLEVVVPMKVISRGR-----GT--------KAPGW-LSYSLRFGGQRHIVHMRI-K----
----K-LLVSTHLPVFT--YTEQRALLQD---QPFM------------------------
----PDDCYYDGYVEGFPAS-LVALSTCFG--GF----R--GMLQINDLAYEIEPIR-VS
-ATFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YKIDHE-DT--QYPPVRCGLTDEE-V-----ARQ-LE----LS-----YNFT
LK-------H-SYFGWWTHR

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 754)

RFLEFAAVVDHTRYLFTQS-NVSIVQRQIFNVVNIVNSIY
RPLDIDIVL------TGIEIWTEKDPFS-TR-----GDLDQVLDLFTLWKSFNFDA-RVH
-HDSVHLFV----KEMF-----NV-KLGV------AY--VNAICQSP-FNCGVEVF----
EDNSL-VLFSITVSHE-LGHNLGM-VH--DT-----------VWCVC--GV-EFCIMYAF
RRE---TTKFSNCSYLDYYN---NSLSFG--TCIQS--PP-N--AQNI---FR----GKL
CGNLVVEE--GEDCDCGSP-H---QC-MN---DPCCQL-NCTLSP-GAACAFG------I
CCK--DCKFRPSGTLCRQQIS-DCDLPEWCNGTSHQCPDDVYVQDGFPCST---DTYC--
---YKKTC-SNHDK-------------QC--KEIFGQ---DA---LSASQ-----NCYKE
INTQGNRFGHCGIV-------------------GAGYKQCLTADIMCGRIQCANVVEIPK
MID--HS---TVYQFRF----N-NTACWGT----------------DY-HLGMT------
-------V---PDIGQVKDGTVCGPE---------KICIE---RKCANMVR-VSQ--TCQ
P-TTCNK-RGIC-----NN--KQH-CHCIRGWA-PP----------FCTD----------
-KG---FGGSIDSGPPPK---NSRERVG--------------------------------
----------------------------------------VSGNVGYIILFWLLPF----
-IVLILGL---------FFIL----------HKETKN-KGKE-EKDRKKEETK-----EK
RKGEEI---------KEKE-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NPN-WGAMFVYL----
MRYHL-FRGACLTAHA-L-------------------------GCYCFRR--TNCLMAPV
PDL---NDMMSNCSYDRIQHR-LN--KWD--LCLSE--PN-I--PYTN-FPYV----ADR
CGDKIKNQ--REECDCGSL-K---DC-AN---DRCCET-SCILSL-GSVCNTG------L
CCH--ECKYAAPGVLCRDLGG-ICDLPEYCDGKNEECPNDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1091)

DGTPCSA---VSVC--
---VRGNC-SDRDM-------------QC--QALFGY---EV---KDGSP-----ACYQQ
LNRIGDRFGNCGVIRRRG---------------GSKPFPCEEDDVFCGMLHCSGVSKIPG
GGE--HTTFRSILVHDI----K-EEKCFGY----------------EA-HQG--------
--------TDLPEMGLVVDGATCGPG---------SYCLK---HNCTFYQD-LHF--ECD
LK-TCNY-KGVC-----NN--KKH-CHCVLGWQ-PP----------TCEL----------
-RG---TGGSIDT--------------SSI------------------------------
-------------------------------------------LVNTNR-ALLLIF----
-TRYILFLVS----LL-FGGFS------Q----ALH---FYG-REREGDNTME-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------M

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

L
F--LLLIL-------SGLGRLT--FA--------------------DH-----YLET--S
HLQITVPQKLGTTTN---DVDV--S-------ETQ-VIYAIQINRKTYTLHLKK-Q----
------LFLDPHFLVYT--YE-SGTLYPD---SSFK------------------------
----KRHCFYQGYAAEIPDS-VVTLSTCS---GL---R---GLLQLVNVSYGIEPLE-ST
-AMFEHML

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQINNN-KA-D-FLPLQDN----Y-P----MIQL-GD--Q-A------YRIL
VK-------SEKKLDAALLT

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

RTLKIQIFMDKALYDYMGS-EVAVATEKIVYIFGLINTMF
SQLKLTVML------TSLEIWSDQNKIL-CT-----GDANELLQRFVSWKGSNLF---HR
SHDMAFLLI----YRDH-----PN-YVGA------TY--HGRACDPK-LAAGI-AL---Y
PKRISLEAFSVVMAQL-LGVNLGL-RYD-DI-----------YNCYCPG---AACIMNPQ
AIRSCGVKLFSSCSVDEFKRVVSQ--PEF--ECLQN--QT-I--SKVV-VQGRA----SE
CGNGIVEK--GEQCDCGPP-E---EC-DF---KKCCHTKNCTLTL-AAECGGG------P
CCDRKTCLLFPRGRICRRSID-PCDFTEFCTGRSEYCVPDMKAIDLEPCNN-KT-AFC--
---YKGVC-RDPAR-------------QC--AELFGK---FA---KGGTY-----LCAEE
VNFMTDDFGNCHRG------------------------NCNFRDTMCAKIVCEWTHTRIT
KTR--N---FDVQYTYL----G-GHICMSA----------------AT-RKDSK------
--------VTNPDNTYVTDGTICDEN---------MFCLS--G-KCTFATN-HKDLAS

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CN
ASKLCNG-HGVC-----NT--KFN-CQCDIGYS-PP----------KCVR----------
-TL-SSPGGSIDDGYWIL---PEGEVMD--------------------------------
--------------------LKIN-K---QHAAA-------RKSGLLIGFCIFLSL----
--FILI---------A-IIALKWNKM------KFL-----K---RRKTISEG--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------M

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

F
L--LLALL-------AELARLH--A---------------------RT-----DSEE--I
FLHVTIPWKIRSNE-----SEN--T-------KKQ-VIYIITIDEKPYTLHLTK-R----
------SFLSPNFLVYT--FNESGYLHSD---SSYF------------------------
----KMHCHYQGYVADFPNS-VATLSICS---GL---R---GFLQFENISYGIEPLE-SS
-ARFEHIIYQVKND-NP-D-IPVLAEN----Y-S----NIWK-KE--Q-P------YKVY
LS-------SQKNTLSKLFPQYLEMHIIVENALYNYMGS-EMIAVTQKIIQIIGLVNTMF
SQFKLTVIL------SSLELWSDKNQIS-TN-----GDADVLLKRFLAWKRNYLI---LR
PHDITFLLI----YRKH-----PK-YMGS------TL--PGTICNKS-YDADI-AM---Y
TDAITLEGFSVIIAQL-LGLKIGL-TYD-DI-----------NNCSCSR---ATCIMSHE
AMGSSGVKIFSNCSMHDYRYFVSK--FDA--KCLQN--FP-K--LQPL-HQKQ-----SV
CGNGIL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

EL--DEECDCGSE-K---EC-QF---KKCCDYNTCKLKG-SVKCGSG------P
CCT-SECEISVAGTPCRKSIDQECDFTEYCNGTSSTCVPDTYALNGHLCRL-GT-AYC--
---YNGQC-QTTDN-------------QC--ANVFGK---GA---QGAPF-----AC-EE
INSLRDRFGNCGFKN-------------------LQPLPCEPKDVLCGKLACVWPHKNTY
QTN--V---QSTVYSYT----Q-GHVCLSI----------------TT-GSSVK------
--------SNGRDYAYVADGTVCGAQ---------MYCEN--K-TCNKVHL-MGY--N

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CN
ATTKCKG-NGIC-----NN--LGN-CHCFPGYR-PP----------DCKF----------
-QI-GSPGGSIDDGNVKK---SDNI-----------------------------------
--------------------VFIK-K---GYNIQ-------RNNWLILSFYIALPF----
--FIIF---------T-IMIIKRNEM------RKSC----S---RENTEYEGK-------
-STIAPE-S-------Y--------DLN------T-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
C--LLFLI-------CGLAGLG--WP--------------------L----VNYSEK--P
QVQVIVPEKIHSV

PF01562 // ENSGT00910000144019_0_Domain_1 (254, 429)

KS----GGD--S-------ESE-VFYKIKIEGTTYVVKLVQ-K----
------MFLPQYFNVYG--YDEEGIMKPL---EQQT------------------------
----QSFCYYQGHIQGYPKS-LAIINTCN---GLR------GLLQFENFSYGIEPLE-SS
-VGFEHLVYQVKHE-KK-D-IPLYAE----KD-V-------S-FKN-T-T------YKIK
SV-------KPS-----DFSQYIETHIVVEKALYKHLGG-DTAVVTQKIFQLVGLMNAFF
SSLNLTVIL------ASLELWIDENKIA-TT-----GDVNELLHRFQNWKKSYLV---LR
PHDMAFLLV----YREA-----PS-YIGA------IF--QGMMCDKD-YGGGI-AL---Y
PRTITLDSFGIILVQL-LSLSMGI-GYD-DI-----------NRCHCPG---AVCIMDPA
AIHSGGMKMFSNCSMDAFAHFLTK--QMS--QCLQN--QP-H--LEPV-YR----ES-AI
CGNGIVEQ--GEACDCGTE-E---EC-QSNE-PVCCEYATCTLKS-SAKCAHG------P
CCE--NCEIK-KGKICRPARD-ECDFDDHCNGSSIQCGEDIYVI

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1073)

NGNKCGG-ER-WIC--
---MQGKC-QSGKS-------------QC--VELFSA---DI---EFGSD-----ECFQE
VNSKNDISGNCGIVSP------------------GIYKPCAPDHVKCGKLICLYHKKEVL
KHK--E---AITIYRNV----S-GQICVGV----------------EY-PLTH-------
---------EENEKMWVQDGTRCAPE---------KVCKN--K-QCVDESV-LGF--DCT
PR-TCNN-NGVC-----NN--KKH-CVCNPQYQ-PP----------NCEN----------
-PQGRSAED--EHELFE-------------------------------------------
-------------------SIPE--K---NYIESP-YH----TKPKKWPFFLIIPF----
--FIIL---------S-VLIAMLAKVYYQ---RKKW----K---SEDYISDED-------
-LESESEPK-------ASKGSKVSVQQT------G-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------D

PF01562 // ENSGT00910000144019_0_Domain_1 (259, 429)

DSEV--A-------YEQ-ISYIIPTDEKPYTVHLKQXX----
-------XXXXXXXXXX--XXX-XXXXXX---XXXX------------------------
----XSHCYYQGYVEGYPNS-VVTLSTCS---GL----R--GILQFENVSYGIEPLE-SA
-FAFQHVLYKLRNE-TN-E-FAIFTEN----S-R----SMET-NGP-M-N------SNIF
IS-----KKSEST-VTDLFPLYLEMHIVVDKALXXXXXX-XXXXXXXXXXXXXXXXXXMF
NQFKVTIVL------SSLEFWSDKNKIS-TA-----GEADELLHRFLKWKQSYLT---LR
PHDIAYLFI----YRDY-----PK-YVGA------TF--SGRMCVTH-YSAGI-AL---X
XXXXXXXXXXXXXXXX-XXXXXXX-XXX-XX-----------XXXXXXX---XXXXXXXX
XXQSRGAKTFSNCSLSDFERFISN--MGA--KCLKN--KP-Q--LQR----AP--P--AV
CGNRKV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

EG--AEICDCGTE-E---XX-XX---XXXXXXXXXXXXX-XXXXXX-------X
XXX-XXXXIAGTDYECRPRAHPECDIPEFCNGSSPQCQPDITIHNGHVCKQ-GK-FFC--
---YDGNC-HDLDE-------------RC--EKLFGK---GS---KNAPF-----ACYEE
IQSQTDRFGNCGKSQ-------------------RAFKPCTWRNLICGRLICTYPTRTPF
QQE--N---IAVIYAHV----R-DTVCITI----------------DY-RLDP-------
---------SVPDPMMVQSGSHCDIG---------RS---------------------T

PF07974 // ENSGT00910000144019_0_Domain_10 (1140, 1188)

C
S-QKCHG-HGVC-----NS--KET-CHCNEGFR-PP----------DCAS----------
-AR--------LSGKQ------G-------------------------------------
--------------------TVME-R--ASR-KI-------GKNWWLLVLYISLPI----
--VIVA---------TIII-VKRNRL------KKWF----T--KEEESLSSES-------
-RSEGSTHT-------YASSSRSESSRQT-----DA------S---QSRSEGSTYTS---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MVYS--YSQ-

PF01562 // ENSGT00910000144019_0_Domain_1 (324, 429)

GIMNSQ---SSGI------------------------
----QSECYYHGYVEGHLNS-LAILSTCS---GL----R--GILHFGNVSYGIEPLD-ST
-VEFQHVL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YQLGDE-NS-E-LGILTKN----S-R----SMEK-Y-A-V-G------YNIF
IS-----EKSETP-VPDLLPL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

YLEMYIVVDKALYDYLGS-DSVTITNKVIEMINIVNSMF
AQLNVMIVL------SSLELWSDTNKIS-TD-----GEADELLYKFLEWKQSHLS---LK
PHDVAFLFI----YRDY-----PD-YVAA------TF--PEKMCFIP-YSAGI-AL---Y
PKGMTLETFAVIVTQM-LGLSLGI-AYD-DP-----------VKCQCSE---AICIMNLE
AMQSGGVKTFSSCSLSDFQRFISK--VGV--GCLQN--KP-Q--MQR--------G--QR
CGNGIREG--NEFCDCGTI-Q---QC-GI---YNCCDHETCQMKI-SSQCLGG------P
CCH--FCLFSGANVVCRAKKDPECDVEEYCTGVSPRCPGDVYIRNGHLCKS-NK-HMC--
---YNGFC-IDLDS-------------RC--EQNFGK---GS---RNAPF-----LCYKE
IHSQIDRFGNCGSRD-------------------GIMTYCGWRNSMCGRLVCTFPTRKPY
IRT--N---ATAIYVRV----K-NYTCITA----------------DF-NRYGD------
--------FVSADTFRIPDGSECDTE---------RICIN--Y-SCVEIGD-LKSSAESC
K-GRCSG-HGLC-----NS--QGT-CYCQRGYR-PP----------YCQG----------
-VP---FFRSAL----WD---IN-------------------------------------
--------------------RYLI----GAS-EK-------ADANWLLSFYIGLSI----
--LIIV---------TLVV-IAWNRL------KTMF----T--KEEESLSTEN-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLLLV-------VHLNGLQ--A---------------------GQ-----HPQK--T
ILQTTVPE

PF01562 // ENSGT00910000144019_0_Domain_1 (249, 429)

KISSPDV----ETD--P-------ENH-MAYLITINENPHFIHLKK-Q----
------SFITSTAVSYT--YDRQDVRHSQ---SLSS------------------------
----LKNCNYNGYVAGFPNS-IVSLTVCS---GL---R---GMIQFENVSYGIEPVE-TL
-SGFIHVIYENTNQ-QA-K-IPDLGEN----Q-T----YSWS-DE--L-D------YQFR
SN-------MKKSGFAVLRPRYIKTDIVVDKKLFDYMGS-DTRVVLQKVIQIIGFINTMF
SKLKLTVLI------NSVEIWSKENRID-FP-----EAPENLLVQFLHWKH---K---YR
PQHISYLLA----FVEH-----PA-STGA------LY--PGNLCKPI-YGAAI-AL---Y
PKGLSLESYSVIVLQL-LSIGIGL-TYD-NA-----------DSCHCTG---DVCLMTPK
AIYSGGVKDFSTCSLDDFKYLST---QDL--ECLQD--LP-M--ERQK-KKPSRPR--RI
CGNGIL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EM--NEQCDCGTL-K---NC-TH---KKCCDPMSCRLKS-KAVCGSG------E
CCG-QDCKVKPVNVLCRKSKN-ECDFEEYCNGNDAYCVPDTFARNGQYCDS-GQ-AFC--
---YSGLC-MTSNN-------------QC--MNLLGK---YV---RGASF-----ACYEE
FNSRNDRFGNCIRK------------------------FCSFENSLCGKLVCTWPFKRLL
MKD--N---MSAAYGQI----R-DDLCISL----------------YK-GGRPL--KT--
-TLSTYSDMSERDETFVKDGTICGPD---------MFCLE--T-QCKETRF-LVDFQQCN
TSRDCND-HGVC-----NN--FNH-CHCDKGYN-PP----------YCES----------
-VK-G-QFGSIDDGHKYY---IDEG----K------------------------------
------------S---AKQ------Q---NRGIH-------PKQQLQLILYITLPL----
--IMII---------S-AVFIKQSKL------SRLC----G---RERSEGTSC-------
-ITEDSVSN-------TKMTTNEGSTLH--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MSVA---AAGRGFASSLSSPQIRRIA
LKEA------------------------KLTPHIWAALHWNL-GLRLV-------PSVRV
G--IL-------------VLLIFLPSTFCDIG-----------------------SVYNS
SYETVIPERLPGKGG------K--------DP

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

GGK-VSYMLLMQGQKQLLHLEV-K----
----G-HYPENNFPVYS--YHN-GILRQE---MPLL------------------------
----SQDCHYEGYMEGVPGS-FVSVNICS---GL----R--GVLIKEETSYGIEPML-SS
-KNFEHVLYTMEHQ-------PVVSCSVTPK-DS-PGDTSHP-PR----------SRKPD
DL-------LVL-TDWWSHTKYVEMFVVVNHQRFQMWGS-NINETVQAVMDIIALANSFT
RGINTEVVL------VGLEIWTEGDPIE-VP-----VDLQTTLRNFNFWRQEKLVG-RVR
-HDVAHLIV----GHRP-----GE-NEGQ------AF--LRGACSGE-FAAAVEAF----
HHEDV-LLFAALMAHE-LGHNLGI-QH--DH-----------PTCTCGP--KHFCLMGEK
IGK---DSGFSNCSSDHFLRFLHD--HRG--ACLLD--EPGR--QSRMR-R------AAN
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 879)

ED--LEECDCGS------DC-DS---HPCCSP-TCTLKE-GAQCSEG------L
CCY--NCTFKKKGSLCRPAED-VCDLPEYCDGSTQECPANSYMQDGTQCDR---IYYC--
---LGGWC-KNPDK-------------QC--SRIYGY---PA---RSAPE-----ECYIS
VNTKANRFGNCGHPTS-A---------------NFRYETCSDEDVFCGKLVCTDVRYLPK
VKP--LH---SLLQVPY----G-EDWCWSM----------------DAYNI---------
--------TDVPDDGDVQSGTFCAPN---------KVCME---YICTGRGV-LQY--NCE
PQEMCHG-NGVC-----NN--FKH-CHCDAGFA-PP----------DCSS----------
-PG---NGGSVDSGPVGK---PADRHLSLSFLAE--------------ES----------
-------------------------P---DDKMED--EE----VNLK-VMVLVVPI----
-FLVVLLCC-----LM-LIAYLWSEVQE-----------VVS---PPSSSESSS------
SSSWSDSD-------S--Q-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--VLFLL-------SGLGGLR--M--------------------------DSNFDS--L
PVQITVP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

EKIRSIIK----EG---I-------ESQ-ASYKIVIEGKPYTVNLMQ-K----
------NFLPHNFRVYS--YSGTGIMKPL---DQDF------------------------
----QNFCHYQGYIEGYPKS-VVMVSTCT---GLR------GLLQFENVSYGIKPLE-SS
-VGFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQVKHK-KA-D-VSLYNE----KD-T-------E-SRD-L-S------FKLQ
SV-------EPQ----QDFA

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYIEMHVIVEKQLYNHMGS-DTTVVTQKIFQLIGLTNAIF
VSFNITIIL------SSLELWIDENKIA-TT-----GEANELLHIFLRWKRSYLV---LR
PHDVAFLLV----YREK-----SN-YVGA------TF--QGKMCDAN-YAGGV-VL---H
PRTISLESLAVILAQL-LSLSMGI-TYD-DI-----------NKCQCSG---AVCIMNPE
AIHFSGVKIFSNCSIEDFAHFISK--QKS--QCLHN--QP-R--LDPF-FK----KQ-AV
CGNAKLEA--GEECDCGTE-Q---DC-ALVG-ETCCDIATCRFKA-GSNCAEG------P
CCE--NCLFMSKGRMCRPSFE-ECDLPEYCNGSSASCPENHYVQTGHPCGL-NQ-WIC--
---IDGVC-MSGDK-------------QC--MDTFGK---EV---EFGPS-----ECYSH
LNSKTDVSGNCGISDS------------------G-YTQCEADNLQCGKLICKYVGKFLL
QIP--R---ATIIYANI----S-GHLCIAV----------------EF-ASDH-------
---------ADSQKMWIKDGTSCGSN---------KVCRN--Q-RCVSSSY-LGY--DCT
TD-KCSN-RGVC-----NN--KKH-CHCSASYL-PP----------DCSV----------
-QSDLWPGGSIDSGNFPP---VAI--P---------------------------------
------------------ARLHER-R----YIESI-YH----SKPTRWPFFLFIPF----
--FIIF---------C-VLIAIMVKVHFQ---RKKW----R---TEDYSSDEQ-------
-PESESEPK-------G-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MVASKMTVIKA-L---FYMRIIP
L--LHWL-----------GVFP--------P-FS------GH-----I-W-AVQP-HYQS
PP

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 429)

EVVIPLRVNGTGR-----SM--------QPPGW-LSYSLHLGGQRHVFHMQV-K----
----K-HLLPRHLPVFT--YTDQGALLED---KPFV------------------------
----QNDCYYHGYVEGDPES-LVALSTCFG--GF----R--GLLQINYVVYEIKPMI-FS
-TEFEHLLYKVDSE-ET--QFPTMKSGFMQEE-I-----VHQ-FEF-Q-ET-----GNFT
LK-------QSHVKGWWIHSIIVEVGAVVDNTLYNHFKQ-NISRLQEDLFLIVNIVDSIY
QELGVKVLL------FGMEIWNRRNHVE-VG------PERRTLTDFCIWKAGNIDA-RMA
-HDTIHLFI----NKTI-----RG-LTGL------GY--VKGMCKSK-YSCAVVTF----
ADRTV-PIIGIAMAHH-LGHNLGM-YH--DY-----------GYCMCSVGY-YRCIMNYD
NPQ---IVQFSNCSFSQFWD---YSVHEA--QCLRY--AV-Y--QKDI---FS----RKR
CGNGIVEE--GEQCDCGSL-Q---NC-SK---DACCLT-NCTLSL-GSACAFG------L
CCK--DCQFLPSGEMCRKEIN-ACDLPEWCNGTSHMCPDDVYVE

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1094)

DGIPCNN---SAYC--
---YEKRC-NDRNT-------------QC--RQIFGQ---EA---KNAQN-----ICYKQ
VNTQGDRFGNCGVE-------------------GSSYLKCNMSNILCGRIQCDNVTEIPL
LRE--HS---TVHGTRF----K-DVTCWGT----------------DY-HIGMT------
-------I---PDIGEVKDGTECGQE---------HVCIQ---RKCVHLSR-LDS--NCS
PT-FCNM-RGIC-----NN--KHH-CHCNYKWD-PP----------NCLI----------
-RG---DGGSVDSGPPPR---RTRIKKI--------------------------------
---------------------------------------------YLL-IPCLI------
-LLLLLLC---------C-LLL--------LCMRK-----KP-KGQKQKSQPQPE--KSK
AKN---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------SPSWDM-KLAER-P---MIPRVLL
L--LVTL-----------WML--LVPGRCSQDRP------SW-----R-Y---------I
SSEVVIPKK

PF01562 // ENSGT00910000144019_0_Domain_1 (250, 426)

EVHRGK-----GL--------QVSGR-LSYSLRFRGQRHVIHLQR-K----
----T-LLWPRQLLLMT--QDDQGVLQMD---YPFI------------------------
----PSDCYYLGHLEGIPQS-MVTVDTCFG--GL----K--GIMKLDDLAFEIKPLK-NS
-PRFEHLVSQIVTD-VN-AVKTT--------------------------------QTLGR
KE--------MSSKDYASHAGAMKSQVQAVLEVYKMSN--NLTACTRYMLEIFSLVDTFW
QSLHVQFYI------FILTIYNVVQPFD--V------SYDVPGGASHTYYVTNFFN-KLR
-PDVSVLVD----KSGP-----QDDASYP------V---SGSMCGSD--GLVTVGI----
LHRNV-LGVAIAATRR-LALSVGL-EYD-NP-----------EYCICQRR--ATCIMYPY
PIL---TDAFSNCSLVKLQQIVSV-PDDL--ACIFH--QN-F--VYLN-----KSITHVR
CGNGIVEE--AEECDCGSF-K---FC-YA---NECCES-DCKLTA-DSICDKG------T
CCA--NCTYTPAGTLCRTIEN-ICDLPEYCDGRSITCPKDIYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1089)

DGTPCTE---DGYC--
---FRGNC-TDRNM-------------HC--KEIFGA---NA---HDAAK-----VCY-S
INKERYRFGHCSREET-----------------SLRYKACTSADMFCGRLQCTNVTHLPR
LQD--H---VSFHQSVL----F-GVPCFGL----------------DE-HRA--------
--------SGTTDAGKVKSGALCASG---------RFCDR---GSCNGSVFKLKY--DCT
PE-KCNF-RGTC-----NS--NRN-CHCHVGWN-PP----------QCVG----------
-EG---PGGSIDSGPLPR---TFRSVRQSR------------------------------
---------------------------------------------QTV-AYLRMIF----
-ARIYTFVAS----LL-FGFASRIKILR------L-----VK-TGKK-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RQAEL-Q---VTLRAPL
L--LLGL-----------WAL--LASVRCSQGRP------LW-----H-Y---------A
SSEVVIPRKETHHGK----

PF01562 // ENSGT00910000144019_0_Domain_1 (260, 428)

-GL--------QFPGW-LSYSLRFGGQRHVIHMQR-K----
----H-LLWPRHLLVTT--QDDQGDLQMD---GPYI------------------------
----PPDCYYLGYLEEVPLS-MVTIDMCYG--GL----R--GIMKLDDLAYEIKPLQ-DS
-RRFEHVVSQMVAE-PN-ATVPTFRDGDNEE--T------DP-LFS---E----ANNSMN
PR--------ISNSLYSSHRGNIKGHVQCSNSYYRIYG--NITTCSKEVVQMFSLIDSIV
QNIDLRYYI------YLLTIYNNRDPAP-VN------QYRI-QSAIFTYFKTTFFD-TFH
-VHSSTLLI----KDAP-----HESNYEP------E---RYSFCTHL--GLLHIGT----
LGRHY-LLVAIIITQT-QMRSIGL-E-----------------------R--TSCIMQRF
PGM---TDAFSNCSYGHAQNCFIR--P-G--RCVFE--TL-A--PVYN-----ETMTTVR
CGNLIVEG--REECDCGSF-K---QC-YA---SYCCQS-DYHLTL-GSICRIG------E
CCT--NFSFSPPGTLCRPIQN-ICDLPEYCHRTTVTCPANFYMQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1094)

DGTLCTE---EGYC--
---YHGNC-TDHNV-------------LC--KAMFGV---SA---EDAPE-----VCY-D
INLESYRFGHCIKQQT-----------------YLSYQACTGIHKFCGRLQCTNVTHLPQ
LQE--H---VSFHHSVR----G-GFQCFRL----------------DE-HHA--------
--------TDTTDVGRVIDGTPCVHG---------NFCNN---TLCNATITSLGY--DCR
LE-KCSH-RGVC-----NN--RRN-CHCHIGWD-PP----------LCLR----------
-RG---AGGSVDSGPPPK---RTHSLRQSQ------------------------------
---------------------------------------------QSE-MYLRVVF----
-GCIYAFIIA----LL-FGTATNVQTIR------T-----TT-T----VTNPE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LEGFL--------F-LS------GW-----S-L-

PF01562 // ENSGT00910000144019_0_Domain_1 (232, 429)

DKLS-QHHS
PPEVVIPLRVSGTGK-----RE--------KASGW-LSYSLHFGGQRHIVHMKV-K----
----K-SFLTRNLPVFT--YTEQGDLHED---QPFI------------------------
----QNDCYYHGYVEGDPES-LVVLSTCFG--GF----Q--GILQVKDSTYEIKPKK-FS
-GTFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 503)

YKLDSE-ET--QFPPMRCGLTEEE-I-----ERQ-LKF-Q-GI-----GNYT
LR-------QSAYEGWWTHLWT

PF01421 // ENSGT00910000144019_0_Domain_5 (503, 760)

VEIAMVVDNKRYETLQS-NETLVHIEIFNVVNLMDSFY
EAMEVDIAL------CGIEIWTRRNLLQ-VD------KIDVLLADFCNWKLNSLAG-RVH
-HDVAHLIV----DKNF-----TD-SLGL------AY--VGTVCIQS-YNCAVLSF----
MGYSV-GGFAIITAHE-LGHNLGM-LH--DD-----------NDCKC--GD-QYCIMYPS
KTL---SSKFSNCSYGSFWN---TN-VRK--SCLRD--SP-N--LQAN---EL----EKR
CGNQVVEE--GEQCDCGSL-K---SC-ND---DPCCLL-NCTLRP-GAVCAFG------L
CCH--NCNISSAGKLCRAEVN-ECDLPEWCNGSSHHCPEDMYVQEGTPCPK---GGYC--
---FEKRC-NNRDE-------------QC--RNIFGK---DA---RSANQ-----SCYEQ
INTKGDRFGHCGIK-------------------NNQYVKCNFQDILCGRVQCENVSLIPL
LGP--HS---TVLRTPL----Q-GVICWGT----------------DY-HFGMT------
-------I---PDIGDVKDGTECGPD---------NICFN---RKCVPMSM-LQT--GCT
NK-TCNN-NGVC-----NN--KQH-CHCNYGWA-PP----------DCQQ----------
-KG---NGGSIDSSPSPE---GKVKEDQDQDQDQDQ------------------------
-------------------------D---QDQDQD--QQKKRRSSVGFLEVFLVPL----
-LAL--LL---------CCLIL--------PCLREE----NE-ETSEESSSA--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

----------------------------------------------------------M-
V---QLH---QDT----------------------DPQ------------IPKGQPCTLN
SSEGGARPAV-----------PHTLF--SSALDRWLHNDSFIMAVGEP-L---VHIRVTL
L--LLWF-----------GMFL--------S-IS------GH-----S-Q-ARPS-QYFT
SPEVVIPLKVISRGR-----GA--------K

PF01562 // ENSGT00910000144019_0_Domain_1 (272, 429)

APGW-LSYSLRFGGQRHIVHMRV-N----
----K-LLFAAHLPVFT--YIEQHALLQD---QPFI------------------------
----QDDCYYHGYVEGVPES-LVALSTCSG--GF----L--GMLQINDLVYEIKPIS-VS
-ATFEHLVYKIDSD-DT--QFPPMRCGLTEEK-I-----AHQ-MEL-Q-LS-----YNFT
LK-------QSSFVGWWTHQRFVELVVVVDNIRYLFSQS-NATTVQHEVFNVVNIVDSFY
HPLEVDVIL------TGIDIWTASNPLP-TS-----GDLDNVLEDFSIWKNYNLNN-RLQ
-HDVAHLFI----KDTQ-----GM-KLGV------AY--VKGICRNP-FNTGVDVF----
EDNRL-VIFAITLGHE-LGHNLGM-QH--DT-----------QWCVC--KL-QWCIMHAY
RKV---TTKFSNCSYAQYWD---STISSG--LCIQP--PP-Y--PGNI---FR----LKY
CGNLVVEE--GEECDCGTI-Q---QC-AK---DPCCLL-NCTLHP-GAACAFG------I
CCK--DCKFLPSGTLCRQQVG-ECDLPEWCNGTSHQCPDDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1094)

DGISCNV---NAFC--
---YEKTC-NNHDI-------------QC--KEIFGQ---DA---RSASQ-----SCYQE
INTQGNRFGHCGIV-------------------GTTYVKCWTPDIMCGRVQCENVGVIPN
LIE--HS---TVQQFHL----N-DTTCWGT----------------DY-HLGMA------
-------I---PDIGEVKDGTVCGPE---------KICIR---KKCASMVH-LSQ--ACQ
P-ETCNM-RGIC-----NN--KQH-CHCNHEWA-PP----------YCKD----------
-KG---YGGSADSGPPPK---NNMEGLN--------------------------------
----------------------------------------VMGKLRYLSLLCLLPL----
-VAFLLFC---------LHVL----------FKKRTK-S-KE-DEEG-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MSLV-------------------ALL
KDSA------------------------KIKFQTWAPQKWNL-RLGLV-PGP-SCIRLEI
---LM-------------LLVIFVPSMYCHLG-----------------------SIYYS
FYEIIIPKRLTVQGG------D--------IPV

PF01562 // ENSGT00910000144019_0_Domain_1 (274, 429)

EG-LSYLLLMQGQKHLVHLKV-K----
----R-NHFVNNFPVYS--YHN-GLLGQE---SPFI------------------------
----SHDCHYEGYIEGVSGS-FVSVNICA---GL----R--GILIKEEKSYSSEPMD-SS
-RRFEHVLYTMAHQ-------ARVSCGVTSR-DSHVVSTSWQ-QG----------SRKPH
DL-------QAL-SYLWSHKKYVEMFVVVNNQRFQMWGS-NVNETVQTVVDVIALANSFT
KRNKHRVVL------AGMEIWT----------------------NFNHWRQEMLFH-RAK
-HDVAHMIV----GHHP-----GQ-NMGQ------AF--LSGACSSG-FVAAVESF----
HHEDA-LLFAALMAHE-LGHNLGI-QH--DH-----------SACFCKD--KHFCLMHEN
ITK---ESGFSNCSSDYYYQFLRE--HKG--ACLFN--KP-W--PRGRKRR------DSA
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ED--TEQCDCGS------AC-HL---DPCCDA-TCTLKE-NVECSHG------L
CCL--GCTFRRKGFLCRPTQD-DCDLPEYCDGSSAECPADSYKQDGTLYDR---IHYC--
---SGGQC-KNPDN-------------QC--VNIYGY---PA---RSAPE-----DCYIS
INTRGDRFGNCGRPTE-D---------------QQTYVICSGDNVFCGKLICTGVQSLPR
VKA--QH---TVIQVPH----D-NDWCWSM----------------DAHNI---------
--------TDIPDDGDVRVGTSCAPN---------KVCMD---HSCVHHSI-LLY--DCR
TEESCHG-KGVC-----NN--LRH-CHCEFGFA-PP----------DCKN----------
-PG---NGGSVDSGPPGM---QVTNNN------ESGIE----GSARVQRQ----------
----------------------------------R--QD----LDYKL-IVFLVPL----
-FLVLLLCT-----PL-TMSYLCSEVQT-----------AVA-EVEESSTETTL------
ESELTSADKI---PTAEEILPPDEEAPPPGEEAPPPA----EAPPPA-------------
------------------------------------------------------------
-------------------------------------EAP----PPEAAPPPEAAPAPEA
------AALPPEPPLAPQAPPPEA---APQPEAPPTPQA-PRPEAPPAPQAPPPEAPPAQ
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------G--GF----H--GMLQIKETIYEIKPKR-FS
-ETFEHWIYEIDSE-ET--QFPPLKCGLTEEE-I-----ARQ-LNS-H-WR-----DSST
MK-------QIVFNDIYTHTWYIEMALVMDHERYIYMAS-NVSDMQDQALLIIHVVNSFY
AQFTVHVFL------IGLEIWTTQNLID-IS------PIEDGLTNFCNWKAANLEA-RLP
-HDVAHLIV----KEDY-----GV-ALGL------AY--VGTICWGR-PSCGINTF----
RPGVVESSFALTITHE-LGHNLGM-RH--DG-----------NFCSC--GR-RGCLMFSY
KVM---TDRFSNCSYLDFLK---TV-TGR--SCLYV--SP-A--PERV---LH----MNR
CGNGLVEG--EEQCDCGSV-Q---LC-LD---DPCCLS-NCTFKA-GANCAFG------L
CCR--NCQFLPSGTVCRPKSD-ECDLPEWCNGTSHMCPEDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

NGILCLG---NGTC--
---YEKRC-NDREE-------------QC--RRIFGK---GA---KSANE-----ICYAK
INSRGDRFGHCGLN-------------------VDHYQTCNMPDILCGRVLCDRIEKIPF
LKD--HS---TVHWTRI----N-DTNCWST----------------DY-HFGMV------
-------I---SDIGEVKDGTACGPE---------HICMG---RRCVSRSL-LNN--TCS
PK-TCNG-KGVC-----NN--KQH-CHCDDQWK-PP----------VCLF----------
-EG---SGGSIDSGPPPA---KRKDSEGKL------------------------------
------------------------------------------WSKHIVLLFLWVPA----
-VLV--L-----------------------CFS-KA---VTE-KKKAKSTEPK----KE-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
-------------------------------------------LWDSASSLPSLHKNKVV
MYKT------------------------SRVLQNWASQMKGL-ALVLV-PGS-SCVRLG

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

I
V--LV-------------LVLTFLPSLSSDLG-----------------------SVYYS
SYEIVIPKALTVEGR------Q--------NPGEE-AFYVISMQGQKQLIHLKV-K----
----T-DYFIKNFPVFS--YHN-GILGQE---MPFI------------------------
----SHDCHYEGYIEGLPGS-FVSVNTCS---GL----R--GILIKEGKSYGIEPMD-SS
-KQFEHVLYTMAHQ-------APVSCSVTSK-DSPVVSTSRQ-QG----------SRKPG
GL-------QEL-SYLWSLTKYVEMFVVVNNQRFQMWGS-DVNETVQRVMHIIALANSFT
RGINTEVVL------AGMEIWTEGDLIE-VP-----VDLQVTLGNFNSWRQEKLLH-RVK
-HDVAHMIV----GQHP-----TQ-GMGQ------AF--LNGACSSG-FAAAVESF----
HHEDV-LLFAALMVHE-LGHNLGI-RH--DH-----------SACICKD--KPLCLMQDN
ITK---ESGFSNCSSDDFYQFLQE--HRG--ACLFN--NPQR--HKGRWRR------ASY
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

EG--EEQCDCGS------AC-YT---DPCCDQ-TCSLKG-SAECSDG------L
CCF--GCRLKNKGSMCRSALG-ECDLPEYCDGTSAECPTDTYKQDGTSCGR---LHYC--
---VGGLC-RNPDN-------------QC--MAMYGD---TA---RSAPE-----NCYIS
MNSKGDRFGNCGRPTL-A---------------MSRYVKCFDDNVFCGKIICTNIRRVPS
IKP--HH---TLIQIPY----E-GDFCWSL----------------DVYNI---------
--------TDIPDEGDVHSGTACAPN---------KVCMN---YSCTDHAV-LNY--D

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CR
PAEMCNG-RGVC-----NN--VRH-CHCEAGYA-PP----------DCRT----------
-PG---NGGSVDSGSPG-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------L---SP-SYAKLGV
F--LL-------------LAEALLPCVCCTQK-----------------------SVY

PF01562 // ENSGT00910000144019_0_Domain_1 (239, 429)

FS
FYEIIIPRRLRGWRR------G--------DPADE-MHYSFSMRRRWHVIRLKR-K----
----K-GLFVQNFPVYT--YSD-GIPRLD---APFI------------------------
----RNDCYYDGYLVGDQGS-FASISTCS---GL----K--GILIIQTMAFGILPVN-AS
-RKFEHVVYRLSKV-------ARDTCGVKER-ESPEFWASMK-GL----------GPMGP
AS-------PSF-LFAWAHPKYLELFLVVDNARFQMWDR-NVTTTIQTLMDALALVNQHM
KQVSLEVVL------AGVEIWSERDLVR-IS-----WDLQETLDSFNRWRALQLPQ-RAR
-HNAAHLVT----GQDL-----GS-HQGQ------AF--VGSVCSPG-NATGVEAF----
PHEDV-PRFAALLAHE-LGHNLGL-KH--DH-----------PGCQCPN--PPPCFMHKS
VPL---EGGFSNCSLWSFQEMLNR--GWG--TCLDR--KP-K--PMSP-FG------RSY
CGNKVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

EE--GEECDCGDG-P---GC-------PCCLP-SCHLKK-GSDCASG------P
CCS--KCRLAKATTPCRPSAD-ECDLPEYCDGTSPHCRPDSYKQDGTPCRD---EGRC--
---YRGRC-RSLQG-------------QC--QELFGA---DS---QAAPA-----SCYR-
MNTLGDRFGNCGSEWQGP---------------VRVFTKCHPEDALCGSLYCKDVQRLPS
IRS--HE---TLVQFLE----G-GTWCWGA----------------DLPRAL--------
---------DTPNGGLVKDGTSCGPH---------KICIN---QSCLDIEA-VLP--SDC
SPLRCRH-RGVC-----NN--LQN-CHCHSGYR-PP----------TCEL----------
-QG---PGGSLDSGPSPR---AGVLHQKLAVL----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
P-----LL-------LLL---S-------------------------GLLKDPRSHQ--T
F

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 429)

LSVTVPLRISSPSS----EFL--E-------PKY-VSYNITIEEKPYILLLKQ-K----
------IFLPHDFRIYT--YNEEGFLTSL---VPFF------------------------
----KNFCFYHGHVADFPKS-LVTLSTCS---GIR------GWLQFENFTYGIEPLE-SS
-TGFEHVVYQVRNE-NT-D-VFLYAE----KD-M-----NMK-SRK-S-P------YKFQ
MA-------NSQLDYLSSFSGYLEMHVVVEKNLYEFMGS-DANLVTQKIAMVTGLVSTMY
SSFNLTIVL------SSLELWIDKNKIN-TA-----GESDELLKRFLKWKESYLV---LR
RHDVAVLLI----YRNR-----FK-YVGA------TF--QGKVCERS-YAGVV-AM---Y
SRTLNLEAFSVIIAQL-LGHNMGL-VYD-DA-----------ESCHCTR---PVCIMNPE
AVKSNGVKVFSTCSLEDFKNFVST--KKA--ECLQN--RP-H--LDPS-YR-----T-ST
CGNGILET--GEECDCGLD-Q---SC-I-----ICCDTMNCKLKS-GAMCAQG------K
CCQ--NCQFSERGTQCRERADLDCDLPEYCNGSSEFCQPDLHVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGHNCRN-RT-AFC--
---YKGKC-PDPND-------------QC--REIFGK---DS---SVGAN-----ECFEE
LNSKADRSGHCGRTPK------------------G-FRQCGWRNLLCAKVMCEYTNPRPF
FNT--Q---ATVIYVNA----D-DHLCITL----------------DF-PTDD-------
---------DTKDPMWVRNGIVCGYK---------KVCLN--R-QCVDLID-LGF--DCH
LK-KCMG-HGVC-----NN--LKH-CHCEDGWL-PP----------NCTI----------
-PTT-GLGGSIDSGIHSK---SDLL-----------------------------------
------------------------------AISSG-HRSNNLGIAIGFPIAVIFTI----
--AIIF---------V-MI----YFRHGI---KCRC----I---LQDTPSDES-------
-FVEDSHSK-------EAKNNPKLKT----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAVSEA-L---VCVRNT

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

L
L--PLWL-----------GVIL--------F-PY------GW-----F-Q-VVHS-QRHG
PPEVVIPLKVTGTGI-----GM--------KIGDW-LSYSLHFGGQRHIVHMKV-N----
----R-NFLSRHFRVVT--YSDQGALLEE---RPFI------------------------
----QNDCYYHGYVEGDPES-LVALSTCLG--GL----Q--GILQTNDIVYEIEPKR-RS
-TTFEHLLYRIKSE-ET--QLPPMKCGLTDEE-I-----ARQ-LNF-P-ES-----ANFT
LM-------QSGYEGWWTHRGLLELAVVVDHNRYLHHLS-NTTAVQYEVLLVVNGVAKFL
SSLDVDVVL------MGIEVWTEKNPVP-ID------TIDGLLEEFCKWKKTSLNN-RIP
-NDVAHLFV----KHSY-----GT-TAGL------AY--IKTICKSY-ASCGVDSF----
MNDNV-YDFAYIVSHE-IGHNLGM-DH--DG-----------PTCTC--GH-KTCIMFPE
NES---ATRFSNCSYADFMDMMGTI-ARK--NCLYI--SS-N--TGNI---FT----LAR
CGNSVI

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

EE--GEECDCGTL-H---LC-MK---DPCCES-NCTLSP-GAACAFG------L
CCK--DCQILPTGEVCRQEEN-ECDLPEWCNGTSYHCPEDVYLQNGMPCKG---GGSC--
---YEKRC-NNREE-------------QC--RNIFGK---EA---KSANQ-----SCYTE
INTQGDRFGNCGFK-------------------HSRYVKCDISDTLCGRIQCDNVTELPL
LRN--HS---TVHWTQF----N-GATCWGT----------------DY-HFGLT------
-------E---PDIGDVKDGTECGAE---------HVCIQ---RKCVHRSL-LVN--YCS
PE-MCNL-KGVC-----NN--RHH-CHCNYDWD-PP----------KCIK----------
-EG---SGGSIDSGPPPR---KKIRK----------------------------------
-------------------------------------------KTQYLQLLWLLPF----
-ILL--L----------CLLV--------LCFLTRR---RKD-KSEEQSVSLSA--EKEE
QNVKTLPR-----EN------------------------------------EQDVA----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------NDCSIMTVGGT-L---IYTRITL
P--LLLL-----------GVSL--------S-IH------GL-----S

PF01562 // ENSGT00910000144019_0_Domain_1 (229, 429)

-Q-ARPS-QHFS
SPEVVIPSKVTSRGR-----GA--------KAPGW-LSYRLRIGGQRHIVHMRV-K----
----R-LLVSTHLPVFT--YTEQHGLQED---HPFV------------------------
----LDDCYYHGYVEGASES-LVALSSCSG--GF----Q--GMLQINDLIYEIKPIR-HS
-STFEHLVYQVGSD-KT--ESPHMRCGLTEAS-I-----TRQ-KEL-H-AS-----YNST
LK-------QSSNVGWWTHWRFVELGVVVDHVRFLYSQS-NVSVVYNEVSHVINIVDEFY
YLMQVDITL------IGIEIWNKRNPIS-TS-----NDLGEVLWDFAVWKDSHLES-RLH
-HDAAHLFI----KEVH-----DQ-TVGM------AF--ITGICDPP-FNCAVSVF----
ESQDL-FLCALTVAHE-LGHNLGM-NH--DD-----------QWCAC--EV-EWCLMYAY
REN---TTKFSNCSYAQYYD---TTRNPG--MCIHS--PP-Y--TGYV---SG----LKF
CGNRVVEE--GEECDCGSV-H---QC-ER---DPCCLL-DCALRP-GAACASG------S
CCK--DCKFLPPGTLCRQQVS-ECDLPEWCNGTSHECPDDVYIQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGTPCMG---GASC--
---YAKTC-NNPDV-------------QC--KEIFGR---EA---RSASE-----ICYSE
VNTQGNRFGHCGIV-------------------ETTYVKCMAPDIMCGRIQCENVHKVPN
LKE--HS---TVHQYHF----N-DTTCWGT----------------DY-HLGMS------
-------I---PDIGEVKDGTVCAPG---------KICIG---RKCASVNP-VPQ--NCE
P-LHCSL-RGVC-----NN--RQH-CHCRHGWA-PP----------NCSY----------
-EG---HGGSVDSGPPPT---NRREGLSVV-G----------------------------
-------------------------------------------NVGYTSALLAIPL----
-ITLLFYY---------FTVL----------SKKEKH-THTQ-VEN--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
P--LFLVL-------SYLGQVI--AA--------------------GK-----DIET--P
LLQITVPEKIDTN

PF01562 // ENSGT00910000144019_0_Domain_1 (254, 429)

IQ---DAKE--A-------ETQ-VTYVVRIEGKAYTLQLEK-Q----
------SFLHPLFGTYL--RDKLGTLQPY---FSLV------------------------
----KTHCFYQGHAAEIPVS-TVTLSTCS---GL---R---GLLQLENITYGIEPLE-SS
-ATFEHIL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YEIKNN-KI-D-YSSLKEN----F-A----NSEQ-ES--Q-S------YRIL
VK-------PEKGSNSTLTKR

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 756)

ILRIKIIMDKAMFDHMGS-EVGVATQKVVHIFGLINTMF
SQLKMTVML------NSLEIWSEQDKIE-TN-----GDADEVLQRFLLWKRKEIS---QK
AQDITYLLL----YKDH-----PD-YVGA------TY--HGMACNPN-FTAGI-AL---H
PKTLAVEGFAIVLSQL-LGINLGL-AYD-DV-----------YNCFCPG---STCIMNPS
AIRSQGIKVFSSCSVDEFKQLASQ--PEL--DCLRN--TS-E--TEFV-VQPQG-G--SY
CGNHLLEV--PEQCDCGPP-E---TC-TH---KKCCNPKDCTLID-AAQCGTG------P
CCDKRTCMIAERGRLCRKSKD-QCDFPEFCNGETENCAPDIKAADLEPCNN-ET-AYC--
---FGGVC-RDPDR-------------QC--TDLFGK---YA---KGSNY-----VCAQE
VNLQNDKFGNCHG-------------------------RCTYSSVFCGKVVCSWNFAEVI
Q-T-EK---YDVQYTYL----G-GQVCVSA----------------HL-RS---------
---------GTRDDTYVHDGTVCGSG---------QVCYR--G-ECLRVHV-LRGTRE

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CE
ADDKCQG-HGIC-----NN--LNN-CQCESGFA-PP----------ECDM----------
-TP-SSPGGSMDDGFWLP---FD---KS--------------------------------
------------------TPLIFK-R---H-GLK-------YKKVLLISFYILLPF----
--LVVL---------A-FMAVKRMID------KRLV----K---QNISKALEH-------
-KEEAFNRG-------SMNPDVVP-GDNT-----DQ------N---LMTVPGS--FNSYA
YHGNTDQNLTMVPGSFNSYSYHGNTDQNFMTVPGNFNSYSYQDVPYYRSRPEDGN-----
-------DSQQ-------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--VLLIL-------SGLGRLT--SA--------------------GP-----HSET--P
VLQITVPRKIQTNTN---DGDV--S-------ETH-VIK-----RSPFKIM----V----
------

PF01562 // ENSGT00910000144019_0_Domain_1 (307, 429)

SFLHPHFLVYL--YNESGTLYVD---SSFS------------------------
----KGHCFYQGYAADIPKS-AVTLRTCS---GL---R---GLLQLDNISYGIEPLE-SS
-PTYEHVVYRIKND-AI-G-HSSFREN----Y-P----VAQY-ID--Q-S------YRIL
VK-------SDINSGAMLSKRTLKIQIIMDKAMYDYMGS-AVAVAVEKVFQIFGLINTMF
SQLNVTVML------SSLEIWSDQNKIS-TS-----GHADEILQRFLPWKQKLLF---QR
SYDMTYLLI----YRNH-----ST-YVGA------TY--HGMACDPK-FATGI-AL---Y
PKKITVEAFSVVMAQL-LGINLGL-TYD-DI-----------YNCYCPR---PTCIMNPD
AIRSHGMKFFSSCSMDGFKQIVLQ--PEL--KCFQD--KT-V--SEMT-YQK-S----AT
CGNGILEP--TEQCDCGYR-K---AC-TY---KKCCNPADCTLIG-FAECGTG------P
CCNNKTCTIHARGHVCRKSID-MCDFPEYCNGTSEFCVPDVKAA

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1071)

DLESCSN-KT-SYC--
---FKGIC-RERDR-------------QC--SQLFGK---FS---KSANL-----LCTEE
VNFQNDKFGDCGQ-------------------------RCHFFDILCGKIVCHWIHSELV
PMT--D---LDIQYTYL----G-GHVCLSA----------------HA-RNASK------
--------QL---RTYTEDITACGQQ---------KVCHS--H-GCRYLSE-LNI---TK
CTTNCGQ-NGIC-----NE--HFH-CQCDPGYA-PP----------DCDP----------
-SI-ASPGGSIDDGFWLS---V---DKS--------------------------------
------------------V-PLFP-K---RRAAP-------KNNGLLISFYIFSPL----
--LILI---------A-IVSLKWNKM------KRFW----S---KVGTVSSNS-------
-ISEDSSSN-------NSQSQS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLLLF-------LHLKGLQ--A---------------------GQ-----NPQK--T
TLQ

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

TTVPEKISSPDV----ETD--A-------EDH-MAYLITINETPHFIHLKK-Q----
------SFITPTAVVYT--YDRNDVQHSQ---PLSA------------------------
----LENCNYNGYVAGFPNS-IVTLTVCT---GL---R---GIIQFENVSYAIEPVE-TL
-SGFVHVIYENTNK-HA-V-IPDLGKN----Q-S----YSWF-DE--S-D------YQFR
SN-------MKKSGFTVLRQRFIMMDIIVDKKLFDYMGS-DTEVVLQKVIQIIGFVNTML
SKLKLTVLI------NSIEIWSKENRIR-LS-----KAVDDLLVQFSIWKH---E---YR
SQHVAYLLA----FEEH-----PA-STGA------LY--PGNLCKLE-YNAAV-AL---Y
PKGLSLESFSVIVLQL-LSIGMGL-TYD-T------------ENCHCTG---EVCLMTPK
AIYSGGVKDFSTCTLDDFKYLSTR--QDL--RCLQD--LP-L--ERK---PARRPR--RI
CGNGIL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 878)

EM--NEQCDCGTL-K---NC-TH---RKCCDPMSCRLKN-KATCGSG------E
CCS-QDCTVKMNDVVCRKSVD-ECDFVEYCNGKDPYCVPNTYARNGQYCES-GE-AFC--
---FEGRC-QTADK-------------QC--MSMLGK---YV---RGASF-----ACYEE
FNSRGDRFGNCIHN------------------------FCAFRNSLCGKLICTWPFKKLV
LKA--N---LSVAYAQI----R-DDLCVAM----------------YK-GGRIP--KT--
-TKTTYSNPADRDETFVNDGTICGPD---------MFCLR--A-SCTETRF-HMDSSKCD
STRDCND-HGVC-----NN--LQH-CHCDIGYN-PP----------FCEE----------
-HK-G-QFGSVDDGHKYH---VEDG----K------------------------------
------------S---YKQ------Q---SHSNL-------KKNQLQLILYISLPL----
--LVMI---------S-AVVIKQSKL------SRVC----D---RERSESDSS-------
-TTEDSGSN-------TNVTSSGGSSSTD-----PP------I---TPNPERILYVFALK
------KH----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MKIIL
L--L

PF01562 // ENSGT00910000144019_0_Domain_1 (185, 429)

LWL-----------GVLL--------S-FC------GR-----T-E-AKQP-QYHS
PPEVVIPLKIPGNSR-----GM--------KPAGW-LSYSLHFGGKRHIVHIKV-K----
----K-YLLSRHLPVFT--YTDQGALLED---QPFV------------------------
----QNDCYYHGYVEGDPES-LVALSSCLG--GF----R--GLLQINDIAYEIKPMM-FS
-TKFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 503)

YKMESE-ET--QFPEMNSDFVQED-T-----LLQ-LES-Q-EI-----NNFT
QK-------QSNSRGWWRHTIL

PF01421 // ENSGT00910000144019_0_Domain_5 (503, 760)

VELAVVVDHTLYLRIHK-NISKFTEDLFAMVNIADSIY
EVLGVKLLL------FGMEFWTTKNYFE-VG------DIRRSLKAFCIWKNDNLTP-RLP
-HDTAHLFM----SKPL-----RG-MSGL------GY--VPGMCQPL-LSCAVLTT----
LNRSI-AIVGIAMAHH-IGHNLGM-FH--DG-----------AYCSC--GQ-VRCIMHTS
NPP---ITAFSNCSLSFFWS---YTIHQA--KCVLY--EI-Y--TKDI---FS----KKR
CGDGIVED--EEECDCGPL-Q---SC-AK---DACCLT-NCTMSY-GSTCASG------L
CCK--DCQLLPSGETCRKQAN-ECDLPEWCDGSSPLCPDDVYVENGIPCNE---SAYC--
---YEKRC-NDRND-------------LC--KQIFGE---EA---KSASH-----NCYKN
INTLGDRFGNCGTN-------------------LSSYLKCNISDILCGRIQCTDVKEIPI
LRE--HS---TVHQSHF----N-DVTCWTV----------------DH-HFGMP------
-------K---PDIGEVKDGTECGPE---------RICIH---KKCVHISR-LDS--DCS
PK-FCNM-RGIC-----NN--KHH-CHCNYNWD-PP----------NCLI----------
-RG---NGGSVDSGPPPK---RPRLKKS--------------------------------
---------------------------------------------YLL-MFSLF------
-WLLLLLC---------C-LLC--------LCLRR-----KK-KEEKVPTQPAEQ--VQK
VPTLPAK--------PPPKAPTQ----------PAEPPPKGPKS---P------------
------------------------------------------------------------
-----------SQTAK------------PPPKV-------------------PKSPSQTA
KA--------------PQKTPSQT----------------TKAPQ---------KTPSQT
AKPQQNVRSQSSISVRQSQSGKQRSSSVKSVPKKKKKK-VIPG--

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--VLLLL-------SGLRALG--EP--------------------L----TNDSER--L
RVQITVPEKMG

PF01562 // ENSGT00910000144019_0_Domain_1 (252, 429)

PLTS----DD---S-------ETE-VSYKIAIEGTTYIVNLTQ-K----
------TFLPYNFKVYG--YDDAGIMKPL---EEEV------------------------
----QNFCYYQGYIEGYPKS-LVIITTCT---GLR------GVLQFENISYAIEPLE-SS
-VGFEHILYQIKQE-NK-D-VSLHTL----KN-T-------D-LKN-M-T------YKIQ
TV-------KPS----SEFFQYIELHLIVEKDLYKHLGS-TTATVTRKIFQLVGLMNGIF
SSFNLTVIL------ASLELWTDENKVP-TT-----GDVNELLHQFQDWKKSYLV---LR
PHDVAFLLI----YREA-----PS-YIGA------VF--QGMVCDKD-YGGGI-AL---H
PKSMNLDSFAVILVQL-LSLSMGI-TYD-DV-----------NRCHCPG---AVCVMNPE
AIHSGGVKIFSDCSMNDFARFTSK--PMS--QCLQN--QP-R--LQTA-YQ-----G-TT
CGNKIVEA--GETCDCGTE-E---EC-NRSP-PVCCDPITCRLKD-TSKCFTG------D
CCE--NCEFKSSEEICRNRVD-ECDLPEFCNGSSADCQEDLFIL

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1071)

NGHPCGE-NK-WIC--
---MNGKC-VSGKT-------------QC--EAAFGE---GV---DFGTR-----ECYEQ
LNSRNDIAGNCGIRKD------------------GSYTPCAPNNLKCGKLVCVYNKMEVN
RNK--H---ATTIYANI----N-GEVCVSL----------------EY-PLNY-------
---------SNSNEMWVQDGTVCDTQ---------KVCRN--K-ECVADSF-LGY--DCT
PA-TCNN-NGVC-----NN--KKA-CQCYPGYL-PP----------DCSI----------
-KIPVYG-----------------------------------------------------
-----------------AQFDPE--R---HYIKGV-YQ----TKPKNWPFLLIIPF----
--LIIF---------S-VLIAIVVKVYFQ---RKKW----R---TEDYISEED-------
-LESESEHK-------DSKEKSG-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--LLLIL-------SGLSLLT--IA--------------------GP-----NSET--P
ILQITVPRKIQTNTD---DGDV--S-------ETH-VTKRSSF--------KIM-V----
------

PF01562 // ENSGT00910000144019_0_Domain_1 (307, 429)

SFLHPRFLVYL--YNESGILHED---SSFS------------------------
----NGHCFYQGYAADIPKS-AVTLSTCS---GL---R---GLFQLDNISYGIEPLE-SS
-PTYEHVVYQIKND-AI-G-HYSFQEN----Y-P----VAQY-ID--Q-S------YRIL
VK-------PDINSGAMLLKRTLKVQIIMDKAMYDYMGS-AVAVAVDKVFQIFGLINSMF
SQLNMTVML------SSLEIWSDQDKIS-TS-----GHADELLQRFLSWKQKFLS---QR
SYDMTYLLV----YRNH-----ST-YVGA------TY--HGMACDPK-FATGV-AL---Y
PKKITLEAFSVVMAQL-LGINLGL-TYD-DI-----------YNCYCPG---TTCIMNPD
AIQSNGMKFFSSCSMDGFKQIVLQ--PER--KCFQD--KT-I--SKMT-YQGKA----ST
CGNGILEA--TEQCDCGNP-E---GC-NF---KKCCNPKDCTLIN-FAECGTG------P
CCNNKTCTIHERGQICRNSID-MCDFPEYCNGTSEFCVPDVKAANL

PF08516 // ENSGT00910000144019_0_Domain_9 (887, 1071)

EYCNN-KT-SYC--
---FEGVC-RDRDK-------------YC--VNLFGK---FA---KSATI-----LCTEE
VNFLNDKYGNCGS-------------------------RCHFFHILCGKIVCHWTHSQPV
SVK--D---YNIQYTYL----G-GHVCFSA----------------HA-RNGSK------
--------QI---TTYTEDLTMCGQH---------KACRS--K-QCLFIGD-INI---TK
CNRTCAG-HGVC-----NE--HFN-CQCDPGYA-PP----------NCEP----------
-AL-SSPGGSINDGYWLL---S---GKD--------------------------------
------------------E-PLFP-K---RRAAP-------KNNGLLISFYIFLPL----
--LILI---------A-IVSLKWNKM------KRFW----S---KAGTVSSRS-------
-ISEDSSST-------NSQSQS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSAEA-P---VTLRAPV
L--LLGL-----------WAL--LAPVWCSQGRP------LW-----H-Y---------A
SSEVVIP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 428)

RKETHHGK-----GV--------QFPGW-LSYSLRFGGQRHVVHMRR-K----
----H-LLWPRHLLMTT--QDDQGALQVD---DPYI------------------------
----PPDCYYLGYLEEVPLS-MVTVDTCYG--GL----R--GIMKLDDLAYEIKPLQ-DS
-RRFEHV

ENSGT00910000144019_0_Linker_1_5 (428, 513)

VSQIVAE-PN-ATGPTFRDGDNEE--T------DP-LFS---E----ANDSMN
PR--------ISTLLYSSHRGNIKGHVQCSNT

PF01421 // ENSGT00910000144019_0_Domain_5 (513, 755)

YYRIYG--NITTCYIAVVQMFSVIDSIV
QNIDLRYYI------YLLTIYNVRDPAP-VN------QYGA-NSAMFTYFKRTFFD-TFR
-VHSSTLLI----KEAP-----HESNYEP------Q---RYSFCTHL--GLLHIGT----
LGRHY-LLVAVITTQT-LMRSMGV-EY--DD-----------NYCTCQRR--AFCIMQRY
PGI---TDAFSNCSYGHAQNCFVN--S-S--QCVFE--AL-A--PVRN-----ESITMVR
CGNLIVEG--REECDCGSF-K---QC-YA---SRCCRS-DCRLTP-GSICHLG------D
CCT--NCSFSAQGTLCRPIQN-ICDLPEYCHGTTLTCPPDLYLQDGTPCTE---EGYC--
---YHGNC-TDRNV-------------LC--KAIFGV---SA---KDAPG-----DCY-D
INLESHRFGHCTREQS-----------------ALSYQACVGIDKFCGRLQCTNVTHLPR
LQE--H---VSFHHSIR----R-GFQCFGL----------------DE-HRA--------
--------TDTTDVGRVIDGTPCSRG---------MACNN---TQCNVAITSLNY--DCY
PQ-KCSY-KGVC-----NN--RRN-CHCHIGWD-PP----------RCLR----------
-RG---IGGSVDSGPPPR---RTRSVKQSH------------------------------
---------------------------------------------QAV-LYLRVVF----
-GRIYTFIIA----LL-FGMATNVRTIR------T-----TA-VKEVTATDPE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLAFL-------SELGRLQ--A---------------------HV-----GSEG--I
FL

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 429)

HVTVPRKIVSND-----SEV--S-------ERK-MIYIITIDGQPYTLHLRK-Q----
------SFLPQNFLVYT--YNEAGSLHSE---SPYF------------------------
----MMHCHYQGYAAEFPNS-FVTLSICS---GL---R---GFLQFENVSYGIEPLE-SS
-ARFEHIIYQMKNN-DP-N-VSILAEN----Y-S----HIWQ-KD--Q-S------YKVP
LN-------SQKKNLSKLLPQYLEIYIIVEKGLYDYMGS-EMMAVTQKIVQVVGLVNAMF
TQFKLTVIL------SSLELWSNENQIS-TS-----GDADDILQRFLVWKRDYLI---LR
PHDIAYLLV----YRKH-----PK-YVGA------TF--PGTICNES-YDAGI-AV---Y
PDAIGLEGFSVIIAQL-LGLNVGL-TYD-DI-----------TQCFCLR---ATCIMNHE
AVSASGIKIFSNCSMHDYRYFVSK--FEA--KCLQK--LS-N--LQPL-HQNQ-----PV
CGNGILES--NEECDCGNK-K---EC-QF---KKCCDYNTCKLKG-SVKCGSG------P
CCT-SQCELSLAGTPCRKSIDPECDFTEYCNGTSSDCVPDTYAL

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1092)

NGHLCKL-GT-AYC--
---YNGQC-QTTDN-------------QC--AKIFGK---GA---QGAPF-----ACFKE
VNSLHERSENCGFKN-------------------SQPLPCERKDVLCGKLACVQPHKNAY
KSD--I---QYTVYSYI----Q-DHVCVSI----------------AT-GSSMR------
--------SDGTDNAYVADGTMCGPE---------MYCVN--K-TCRKVHL-MGY--NCN
TTIKCNG-KGIC-----NN--FGN-CQCFPGHK-PP----------DCKF----------
-QF-GSPGGSIDDGNFQK---SG-E-----------------------------------
--------------------FYTE-K---GYSTH-------WNNWFILSFYIVLPF----
--FIIF---------T-IVIFKRNEI------RKSC----N---RENAECKR--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWA-QRP-LMGVLWL
Q--VLWVL---------------LCLVCCSHDPP------KW-----R-F---------T
SSEIV

PF01562 // ENSGT00910000144019_0_Domain_1 (246, 428)

IPKKVPQRRG-----EI--------KMPNQ-LAYSIRFRGQRHVIHMKL-K----
----K-NLIPRHFPVVT--NNDQGANQED---YPYV------------------------
----PQDCYYYSYLEGVPGS-VATLDTCYG--GL----R--GMLQVDDFTYEIKPLE-AS
-SKFEHVVSLLVSE-DT--ADEDERCKIEDE-------ETYQIPEE--------VNLAES
PR-------AGPVYLWRLHMKHMKLHFTITSSVYSKN-E-NKTQVIENVVIINNILDSIF
RQGNLYSNI------RILCIWEKKDEFE---L-KSYKSASAATHEFGLWKFYKLWK-VFT
-HDTSILYV----GYKI-----GGSKYYA------S---SSGYCNPN-WGAAYVHF----
EDYHI-FKIAALTAHT-IGHNMGI-GH--DN-----------PSCVCFRR--HHCVMNSI
PGL---LDMFSNCSYNILHWM-VH--KWD--PCLSL--PN-V--PYYN-FPYI----V--
-----LNV--NEQCDCGSL-K---EC-AN---NSCCST-NCAFTS-GSTCDIG------G
CCD--HCKLAGAGKLCRDVRG-ICDLPEYCDGTGNICPDDLYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1091)

DGTPCSP---LSVC--
---VRGNC-SDRDL-------------QC--QALLGY---QV---KDALP-----MCYEK
LNVIGDRFGNCGLKYVRG---------------GIKPMKCEIDDVLCGMLHCSNVHKIPG
VAE--HSTFHHIYVGDA----K-LESCFGL----------------DT-HYG--------
--------EELPEMGLVVDGATCGPG---------QYCLN---KNCTFHRD-FPF--TCD
VK-TCNY-KGVC-----NN--LEK-CHCLRGWK-PP----------DCEQ----------
-KG---TGGSEDSGPPPD---KELSMKAKI------------------------------
-------------------------------------------QVTVNK-ALVVIL----
-SRITAFLLV----IC-IGAAI------K----AKM---TAD-AKKK-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------R-GTGA--------FRATL
V--LLGL-----------WAL--LALAQCSQGHP-----

PF01562 // ENSGT00910000144019_0_Domain_1 (220, 428)

-SW-----R-Y---------V
SSEVVIPRKETHHGK-----GF--------RVPGW-LSYSLHFGGQRYVIHLRR-K----
----A-LFWPRHLLVTT--QDEQGALQMD---YPYV------------------------
----PSDCYYLGYLEEIPLS-MVTVDMCYG--GL----Q--GIMKLDDLAYEIKPLK-DS
-LSFEHVVSQITAE-RD-AVGPMYSLGHRED--A------DA-LLP---A----AHTAST
AR--------ISTTTYASHAGRIRGQVQCSYLMYQVYN--NMTFIVRFLVHMFNMVDSYF
SSLHVTYTI------FLLTIYNVRDPFL--I------DIRVPDGEAFEYYSRHFRI-PYG
-ITSSTVVN----KNYP-----HEGSYEP------P---HSTMCRNE--NLIFVAS----
LGRHF-VFLSTVAANE-IMRNYGV-SY--DE-----------PECTCLRR--TICIMDRF
PLL---TDRFSNCSLVDMNNIAMR--ASG--KCLFP--PY-R--ESLN-----KSLTFVR
CGNNVVED--QEQCDCGSL-K---QC-YH---TDCCDT-NCHLTP-GSQCYVG------S
CCT--NCTYSALGTLCRPMQT-TCDLPEYCTSGSQNCPEDFYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGTPCSQ---VGYC--
---YHGNC-TDRSI-------------HC--KEIFGP---DA---EDGSS-----DCY-D
INMESHRFGHCSREED-----------------SNTYQPCTIENRMCGRLQCRNVTRLPQ
LQD--H---VSFHQSMT----STGTVCFGL----------------DE-HRS--------
--------TGTNDAGRVRPGTLCAPG---------TICVN---GQCSGPVEDLNY--DCT
PQ-KCNY-RGVC-----NN--NRN-CHCHVGWD-PP----------LCLR----------
-RG---FGGSADSGPPPK---RFREVKLSE------------------------------
---------------------------------------------QSV-FYLQVAV----
-GRFFALLAA----LL-FGVATNVRIIL------V-----GK-EAEESESDE--------
----E-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAVAEV-L---VHVRITL
L--TLWL-----------GVFP--------F-IS------GW-----P

PF01562 // ENSGT00910000144019_0_Domain_1 (229, 429)

-Q-KGHS-QYHS
HPEVVIPLRITGTGK-----GM--------KTPGW-LSYSLHFGGQRHIIHMKV-K----
----R-FLVSRHFPVFT--YTDQGALQED---QPYV------------------------
----QSDCYYHGYVEGEPES-IVALSSCFG--GF----Q--GMLQISDIVYEMKPKR-FS
-ATHEHLI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YRLHYN-ET--ELPSMKCGLTEEQ-I-----AQQ-LVF-H-ET-----NNVP
LK-------QSNYEGWWTYK

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

RAVEFFVAVDHQRFIYQNR-NASVVLQEVFIIVNEIDGLY
AAIEVDFIL------CALAIWTERNPIR--S-----ENPERLVDLFCEWKSISVNR-RIT
-NDVGHLFI----RQSF-----GS-KFGA------AT--LFGMCYSN-LNCGVDSF----
MLDEQYFRFAHSVSHE-IGHNFGM-RH--DG---------A--DCTC--GK-SHCLMSEG
ESF---ARSFSNCSYAAFQA---VL-YGS--TCLYN--AP-S--LL---------K--DI
CGNGIPET--GEQCDCGTF-Q---MC-TN---DPCCQT-NCTLTP-GAVCGFG------L
CCK--DCQFRASGELCREKEN-ECDLPEWCNGEQHECPEDVFMQHGYNCSV---TGVC--
---FNKTC-HVRNE-------------QC--RQVFGM---EA---KDADE-----ACYRA
VNTLGDRFGNCGND-------------------SKKYTACNSSDILCGRIQCENVKDVPD
LAD--HT---TVVLSHV----G-NHDCWGT----------------EF-HFGMT------
-------G---SDIGVVKDGTECGDK---------SICMH---RRCVPVGK-QR---CSA
KG-QCND-KGVC-----NN--KQH-CHCDSKWA-PP----------YCEE----------
-KG---NGGSSDSGPPPP---RVKEESPT-------------------------------
-------------------------------------------RGNNLTLLFLIPL----
-LLLLLLL---------GLIIF--------LSTKRK---ASE-REEKKNEAPSQ----KA
QDAEAPPQ-----ETDTK------------------------------------AT----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLVLL-------TGLGGMH--A---------------------DL-----NPHK--I
F

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 428)

LQTTIPEKISSSDA----KTD--P-------EHN-VVYMITIEGKPYFVRLKK-Q----
------SILSSASVINS--YDKNDIRHSK---PLLV------------------------
----QMDCNYNGYAVGIPNS-LVTLSICS---GL---RL--GTMQLKNVSYGIEPME-AV
-SGFIHKIYEEKYA-DT-N-I-LLEEN----D-T----YSWF--N--S-E------YQVR
KS-------SEKTDFIKLFPRYIEMHIVVDKNLFDYMGS-DINAVTQKVIQIIGLVNTML
TQLQLTVMI------SSIEIWSNKNKIS-TT-----GHAEDVLLQFFEWKKDHLN---LK
PHQIACLLF----YRKL-----PT-LIGA------TF--PGQVCNKD-FAAAV-AL---Y
TEGLSLESYTVIIVQL-LGLNLGL-TYD-KT-----------DTCHCSE---DVCTMTPK
AVYSGGVKDFSICSLDDFKYISSH--NGL--TCLQT--NP-L--EMPT-YTQ---R--RI
CGNGLLEG--GEECDCGTK-D---NC-TH---KLCCDPSTCRMKG-NVQCGSG------D
CCS-KDCKLKPANTICRKSVDKECDFTEFCNGDLPYCLPDTYVR

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1068)

DGEYCDS-GG-AFC--
---FQGKC-RTFDK-------------QC--DDLIGR---GS---RGAPI-----FCYDE
INTRGDNFGNCGTA------------------------YCLFQHILCGKLVCTWEHRDLI
SRP--N---LSVIYAHV----R-DQTCVST----------------YL-PRRTPPPVNSH
ISVTSYYSVEDRDETFVQDGSVCGPD---------MYCFK--T-RCKHVRF-LMNFKLCN
ASDHCNR-HGVC-----NN--FNH-CHCEKGYN-PP----------YCKP----------
-KQ-G-AFGSTDDGHLVP---PTE------------------------------------
------------------KSYMEE-G---RHATF-------QKQRFQLIFYISLPV----
--LLIT---------T-AILIKRKKL------RELC----Y---RGETESDSS-------
-VSEESSSN-------SKSSLSER------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RPAEV-R---VTLRAPL
L--LLGL-----------WAL--LALVWCSQGRP------LW-----H-Y---------A
SSEVVIPRKETHRGK-----GL--------

PF01562 // ENSGT00910000144019_0_Domain_1 (271, 428)

QFPGW-L----------HVVHMRR-K----
----H-LLWPRHLLVTT--QDDQGALQVD---DPYI------------------------
----PPDCYYLGYLEEVPLS-MATIDTCYG--GL----R--GIMMLDDLAYEIKPLQ-DS
-RRFEHVVSQIVAE-SN-ATGPTFRDGDNEE--T------DP-LLS---E----ANDSMN
PR--------LS-------P----------------------------------------
---------------------SLRDPAP-VN------DNRY-HSAMINYFRRTFFD-TFR
-VHSSTLLI----KDAP-----HESNYEP------K---RY

PF01421 // ENSGT00910000144019_0_Domain_5 (642, 755)

SFCSHL--GLIHIGT----
LGRHY-LLVAVITTHK-LMRSFGV-GY--DY-----------KYCTCQRR--TSCIMQRY
PGM---TDAFSNCSYGHLQNCFVN--S-A--QCVFK--AL-A--PVYN-----ETVTTVL
CGNLIVEG--REECDCGSF-K---QC-YA---SRCCRS-DCHFTP-GSICHLG------D
CCT--NCSFSPPGTLCRPIQN-ICDLPEYCHGTTLTCPPDFICKMEPRALK---KATA--
---------------------------------IMGT---A-------------------
------LTAMCSAR-------------------RSLLSACVGKDKFCGRLQCTNVTHLPR
LQE--H---VSFHHSVR----G-RFQCFGL----------------DE-HRA--------
--------TGPTDVGRVIDGTPCTDG---------NFCNN---TQCNATITSLGY--DCH
PE-KCSH-RGVC-----NN--RRN-CHCHIGWD-PP----------RCLR----------
-RG---AGGSADSGPPPR---RTRSVKQSQ------------------------------
---------------------------------------------QSV-LYLRVVF----
-GRNCTE---------------------------------------VTVTDPE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MLSLTWGM-RLVER-P---VVPRVLL
L--LFAL-----------WLLL-LVPVWCSQGHP------TW-----R-Y---------I
SSEVVIPRKEIYHTK-----GL--------

PF01562 // ENSGT00910000144019_0_Domain_1 (271, 427)

QAQRL-LSYSLHFRGQRHIIHLRR-K----
----T-LIWPRHLLLTT--QDDQGALQMD---YPFF------------------------
----PVDCYYIGYLEGIPQS-MVTVDTCYG--GL----S--GVMKLDDLTYEIKPLN-DS
-QSFEHLVSQIVSE-SD-DTGPMNAWKHWSHN-T------GS-PSS---R-L--EYADGA
PR--------ISSKNYATHPAAIKGHFQATNSVYNSAAGDKLSSTVGYLFQVISLMDTYL
TNLHMRYYV------FLMTVYTNSDPFR--L------EFAVPGGSAYNYYVSVFYN-KFK
-PDAGVLLN----KYGP-----QDNQVNP------A---ERSICSSL--ALICIGK----
YDRNP-LFLSPIITNR-VGRSLGL-KY--DE-----------GYCVCQRR--NTCIMFRH
PQL---TDAFSNCSLAEISNILNT-PGLM--PCLFY--DR-H--VYYN-----TSLTYKF
CGNFKVDN--DEQCDCGSQ-K---AC-YS---DPCCGN-DCRLTP-GSICDKE------L
CCA--NCTYSPSGTLCRPIQN-ICDLPEYCNGTKYICPDDTYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCSE---DGYC--
---YKGNC-TDRNI-------------QC--MEIFGV---SA---KNANI-----KCY-D
INKQRFRFGHCTRAEE-----------------SLTFNACADQDKLCGRLQCTNVTNLPY
LQE--H---VSFHQSII----S-GFTCFGL----------------DE-HRG--------
--------TETTDAGMVRHGTPCSKS---------KFCDQ---GACSGSLSHLGY--DCT
PE-KCSF-RGVC-----NN--HRN-CHCHFGWK-PP----------ECKE----------
-EG---LSGSIDSGSPPV---QRHTIKQKQ------------------------------
---------------------------------------------EPV-VYLRILF----
-GRIYFLFVA----LL-FGIATRVGVTK------I-----FR-FEDLQATLRSGQ-----
GPARDK-PK---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
R--VLLLL-------GGLGGLS--GY--------------------SPRHREHNYER--L
HVQVTVP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

VKIRSIKN----GG---F-------ESH-VAYNITIEGKTYTMNLTQ-K----
------VFLPHNFKVYG--YDGTGIMKPL---DKDF------------------------
----QNFCYYQGFVEGYPNS-MVMVSACT---GLR------GLLQFENATYGIEPLE-SS
-VGFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQVKYK-NE-T-VSLYTE----KD-I-------E-IKN-L-P------YKIQ
SI-------EPQ-----EMA

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

QYLEMHIIVEKHLYDHMGS-DTTIVTQKIFQLIGLTNAIF
TSFNLTIIL------SSLELWVDENKMS-TA-----GDANELLHRFLRWKRSYLV---LR
PHDVAFLLV----YRER-----TD-FVGA------TF--QGKMCERD-YGGGV-AM---H
PKAIGLESLAIILAQL-VSLNMGI-SYD-DV-----------KKCHCPG---TICIMNPE
AIHSSGVKIFSNCSMEDFAHFVSK--QKS--ECLQN--HP-R--LEPS-YK----QA-AV
CGNKVVEQ--GEACDCGTE-Q---EC-GANR-PVCCEHSTCALTA-GSECASG------P
CCS--ECKFSKKGHVCRSAAN-ECDLTEYCNGSSQVCQENVFIIDGHPCSE-NK-WIC--
---IGGVC-RSGDK-------------QC--EDLFGQ---GS---IFASE-----DCYNE
LNSKTDISGNCGITDD------------------G-YKACEAKDRKCGKLICKYGGSHIL
QLK--D---ATAIYANI----T-GDICVSL----------------EY-NKGH-------
---------AEIKNMWVKDGTVCGTK---------KVCKE--K-ECVDNSY-LNY--DCT
PE-TCNN-QGVC-----NN--KRN-CHCNADFV-PP----------KCQE----------
-EREGSGGGSIDSGNHEN---TAAA-----------------------------------
---------------------TE--R---RFIERTYYE----SRTSRWPFFLVIPF----
--FVIL---------C-VLIGMLVKVHFQ---RKKW----K---SEDYTSDEQ-------
-LESETESK-------E-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
H--ILLLL-------SGLSGLG--RP--------------------SELPIKGTPGR--L
HVQVTVPEKI

PF01562 // ENSGT00910000144019_0_Domain_1 (251, 429)

RSIQS----GG---Y-------ESH-VVYNLTIEGKTYTLNLMQ-K----
------MFLPPNFRVYS--YDNTGIMRPL---DQHF------------------------
----QNVCYFQGYIEGYPNS-MVIVSTCT---GLR------GFLQFGNVSYGIEPLE-SS
-IGFEHVIYQVEPK-KG-D-ALLYAE----KD-M-------E-LRD-L-K------YKIQ
SV-------KPQ----KAVSRYLEIHIVIEKEMYEHIGA-DTAVVTQKIFQLIGLMNAIF
APFNLTVIL------SSLEFWMDENKIS-TI-----GDANELLYRFLKWKQSYLV---LR
PHDMAFLLV----YRET-----SD-FIGA------TF--QGKMCDKN-YAGSV-AL---Q
PKAVTLESLAIVLVQL-LSLSMGI-SYD-NV-----------SKCHCGV---SICVMNPE
AIHSSGIRTFSNCSMEGFSSFISS--QNS--YCLQN--RP-Q--LQLS-YK-----A-KV
CGNGQL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EE--GEECDCGT--K-------CEN-PSCCDPATCQLTK-DSLCAEG------P
CCE--NCKVKAKGEVCRNSRG-NCDVTEYCNGTSAVCEEDFYVHDGHPCGT--Q-WVC--
---FNGSC-KDGTE-------------QC--RNLFGF---ES---DFGTN-----ECYDE
LNSKTDITGNCGISPS------------------G-YTACAPNNLKCGKLICKYRSENVV
KMR--S---AAVIYANI----S-GEICVSL----------------EY-IPGH-------
---------KDSSNMWVQDGTVCSTN---------KVCMN--K-ECVEDKI-FNY--DCK
PE-NCNN-HGVC-----NN--KKH-CHCNPTYL-PP----------DCQN----------
-TEEKWPGGSVDSGNQQR---AE-------------------------------------
-------------------SIPA--R---PHIASA-YH----PKPTRWPFFLIIPF----
--YIVI---------C-VLIAVLVKVHSQ---RKKW----R---TDDYSSDEQ-------
-FESETETK-------D-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------IVAMSES-L---IHLRKAL
L--PVWL-----------GVLL--------F-PS------IW-----P-L-AWCA-EFKS
LP

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 429)

EVVIPLRVTVSSR-----DR--------SLADW-KSYSMHFGGQRHIISMKP-K----
----N-FLVSRHLSVFT--YSDQGDLFED---QPFV------------------------
----QNDCYYLGFVEGNPES-MVALTTCFG--GF----Q--GTLQINDTAYEIKPKR-PS
-STFEHLIYKIDSE-KV--QLPSMRCGITDEE-I-----TGQ-VRF-Q-ED-----DNST
IK-------QMVYEAWWTHRLNIELALVVDHEQFLHRGS-NTSLVMQDVFMAMSGLNFYL
FPADINVDL------LGLVIWNKVNPIP-VK------DVYTLLPAFCKWKRENLDF-YLQ
-HDIAHLFV----NYNF-----SN-YFGI------AY--VGTICNKT-FSCGVESF----
LGENF-FTFGHIVAHE-IGHNLGM-PH--DG-----------IFCSC--GG-GSCVMSAT
TNS---SRKFSNCSYAVLWE---IT-AKA--SCMHN--KL-N--TSDI---LP----MKF
CGNRVVEE--GEECDCGSP-M---EC-EY---SLCCLP-GCTFKS-EANCDGG------L
CCS-HLCQILPPGTMCREQEN-ECDLPEWCNGTSQECPEDVFLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1094)

DGSSCSD---GGYC--
---YEKRC-NSHDE-------------QC--QRIFGK---DA---RKASD-----SCYQE
LNTFGDRFGNCGIM-------------------DNTYVKCNSSDILCGRVQCKEVKRLPY
LRS--HY---TVHWTHF----N-DVPCWST----------------DY-HFGMT------
-------I---PDLGDIKDGTKCGPE---------HVCIN---RKCVNKSV-WAS--DCS
EE-TCNK-NGVC-----NN--KHH-CHCDDGWS-PP----------TCLV----------
-NG---TGGSIDSGPSLG---NKDKEREKE------------------------------
---------------------------------KE--KD-VTGRNLTQWIFPVS-F----
-ASL--LL---------L--LF--------FWLYE----GP-------------------
----TP-------------S----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
F--LLVLL-------AQLGW

PF01562 // ENSGT00910000144019_0_Domain_1 (201, 429)

LH--A---------------------RP-----NSQR--I
FLQTTLPEKISSFDT----DRD--P-------ENN-TAYIIAIEEKPYFLHLKK-Q----
------SFLTSSSVIYS--YDEKDIQHSK---PLLG------------------------
----QMDCSYGGYIAGFPNS-LATINTCS---GL---R---GILQFNNISYGIEPME-SE
-SGFVHMI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

FQENND-NL-D-IPLLAEN----D-T----YAWF-DN--S-Q------YQVR
SD-------SKRTQFSKLFP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 755)

RYLEMHIVVDKNMFVYMGS-DLKTVTEKIIQIIGLVNSML
TQLKLTVVI------SSIEIWSNENKIS-IT-----GNPDDILFRFLNWKQQHLV---LR
PHHIAFLLA----FQKH-----PN-FIGS------TF--PGKICNKN-YAAGV-VL---Y
PKGLTMESYSVAIVQL-LG-SLGL-NYD--T-----------DICYCSG---DVCTMTPK
AMHFRGVKEFSTCSLEDFKYFVSQ--PDL--NCLRS--HL-V--DTPV-YRQ-E-R--RA
CGNGKIER--GEQCDCGTL-Q---NC-TH---KKCCDPRSCTFKG-KVICGSG------E
CCT-QDCKLKPLGVLCRKSRDEECDFNEFCNGNQSYCVPDTHARNGQPCDS-GD-SYC--
---YKGFC-RMFNK-------------QC--KKLIGG---DS---TGGSF-----TCFDE
INTRGDRYGNCGRG------------------------FCAFSDLLCGKLVCSWPHKGLI
SRP--N---LSVIYSHI----R-DEICVST----------------FI-SIEKPSDKE--
-SFTTYRSAADRDETFVEDGTICGPE---------MYCRE--F-RCLEIRH-EIDYSVCD
TTTHCNG-RGIC-----NN--FNH-CHCKMGFA-PP----------DCRK----------
-ME-G-EFGSIDDGHPIK---TQ-------------------------------------
------------------KGE-RG-R---RYASA-------RKPWLQLILYISLPV----
--LMIT---------AAALLLKQKKL------KQLC----Y---GGETESERS-------
-VSEESNN--------SKEMPSEKNTV---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
E--L

PF01562 // ENSGT00910000144019_0_Domain_1 (185, 429)

WFNL-------HKRC------C--------------------MA---ARQSTDSQV
PLHITVPQRVLSNTT----GET--VLIKLFPRKDT-QSYILSVEGRLYTIHLKQ-Q----
------FFLPADFSIYT--YNKTGSLRSD---SPYI------------------------
----KGDCYYRGYIEGIPGS-AVTLSTCM---GLR------GLLQFHNASYGIEPLG-SS
-PSFQHVV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YPLLLS-KH-R-REVLLH-----V-I-LDKNLYR-HLG---D------DKYI
MT-------RKAKEAVPRSP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

RYLEMHVILDKALYDYMGA-DKYVVTTKMVQLFSYVNSMF
TRLNLTIVL------TSLEFWTEKNKIP-TT-----GAAEELLQRFLEWKSTHRT---SR
LQDITFLFV----YREQ-----SH-SMGA------SS--ARKLCLKD-RAGGV-AL---Y
PRTTTLEVFSVAVAQL-LGLSLGM-SYD-DP-----------GSCGCVG---ATCIMQSS
AVHSAGTKAFSNCSIRDFERFLTS--GEG--QCLLN--RP-L--VNVS-------YKAPV
CGNKVVEL--GEACDCGSA-E---EC-RR---DPCC-TVGCKTRK-GVQCLSG------P
CCS--RCRFMKKGTLCRTSSEDECELKEYCNGTSGECAPNLWVMDGHPCRQ-NT-AFC--
---YRGVC-QTADK-------------QC--QEIFGK---DA---KNGPL-----ACYEE
VNGQRDRMGHCGSD-H------------------SGYHSCAWSDLRCGKLICEYLGTVPF
TKE--R---AAVVYVRM----Q-NVLCVTL----------------DY-MQPR-------
---------TERDPMLVRDGSVCDDR---------KVCME--Q-KCVSAAA-LNY--SCD
IRRKCHD-HGVC-----DS--KGD-CHCDVGWK-PP----------DCRE----------
-KA-ESQE--LFL-----------------------------------------------
-----------------------A-D---PWNKSS------LKTWQLLTLCLSVPI----
--LIGL---------I-FVVIKRKELK------QCL----S---TE-Q------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MECFIMLGADA-R---TLMRVTL
L--LLWL-----------KAVP--------S-LI------DL-----S-Q-TGST-QYLS
SPE

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

VVIPLKVTSRAR-----GA--------KNSEW-LSYSIVFGGRRHVVHMRA-K----
----K-LLVSTHIPVLT--YTEEHAPLSD---YPFV------------------------
----PSDCYYHGYVEGALES-LVAFSACNG--GL----Q--GVLQMNGFSYEIEPIK-HS
-STFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YTLNNN-KT--QFPPMLCSLTEKR-L-----PYQPFGL-E-EA-----EKSA
MK-------QNYG-KLWPHMW

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

FLELAIVVDYGFFTNAQQ-NLSKVRGDVVLIVNMVDSMY
KLLDTYVTL------VGIEIWNRGNVFP-ME------NIHQVLEDFSQWKQISLS--QVH
-HDAAHIFI----RSSL-----IS-VLGI------AY--IAGICRPP-LDCGVENF----
QGDAW-SLFANTVAHE-LGHTFGM-KH--DE-----------ESCSC--GE-SGCVMSTF
RVP---AERFTNCSYSDFMK---TTLNQG--TCLYN--HP-R--QGEG---FL----VKR
CGNGVVES--EEECDCGSV-Q---EC-EQ---DPCCFL-NCTLRP-AAACGFG------L
CCK--DCKFMLLGELCRPKIN-ECDLPEWCNGTSHQCPEDGYVQDGVPCGA---GSYC--
---YQKQC-NNHDQ-------------QC--REIFGK---GA---RSTSH-----NCYKE
INLQGNRFGHCGTN-------------------GTAFLKCRMSDVFCGKVHCENVEDIHH
PQA--PY---ILQNIYA----N-GITCWST----------------GH-CLGMG------
-------V---PDVGEVKDGTTCGVG---------KICIH---KKCVSLSV-LSN--ACF
PE-TCHR-KGVC-----NN--RHH-CHCDYGWS-PP----------FCLH----------
-RG---YGGSIDSGPTSQ---KRRVIIT--------------------------------
-------------------------------------------------VLSITVP----
-VLSVLIC---------LFIAGLY------RIYCK---IPSG-PKETK--ASSPG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------

PF01562 // ENSGT00910000144019_0_Domain_1 (309, 429)

ISRHFRVFT--YSDQGALLED---QPFI------------------------
----QNDCYYHGYVEGDPES-LVALSTCLG--GF----Q--GILQTNDIVYEIQPKT-LS
-TTVEHLLYRIKSE-ET--QLPPMKCGLTGEE-I-----ARQ-LKF-Q------------
----------SGYEGWWTHRRLLELAVVVDHSRYLHHQS-NTTGVQYEVLLVVNGVHDIY
KPIDVDVVL------MGLEVWTEKNPFP-TD------KVDAVLSPFCNWKKAGFNK-RVP
-HDIAHLFV----RHHY-----GE-DVAL------SF--VGTICNPD-LNCAVDSF----
INDDL-YSFAYIVSHE-IGHTLGM-PH--DD-----------KTCTC--GN-SQCIMYGY
ESG---ATKFSNCSYAGFMN---KI-ASQ--NCLYF--PS-N--TGKI---FT----LAR
CGNNVIEE--GEECDCGAL-H---LC-MK---DPCCES-NCTLSA-GAACAFG------L
CCK--DCQILPTGEVCRQEEN-ECDLPEWCNGTSYHCPEDVYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

NGMPCKG---GGYC--
---YENRC-NNREQ-------------QC--RNIFGK---YA---KSANQ-----RCYTE
MNTRGD-FGNCGLM-------------------NGGYIKCSISDTLCGRIQCDNVIQIPL
LRD--HS---TVHWTQI----N-GVTCWGT----------------DY-HFGMT------
-------D---PDIGDVKDGTECGAE---------HVCIT---GKCVHRSL-LVN--NCS
LK-TCNL-KGVC-----NN--RQH-CHCNSEWD-PP----------FWV-----------
--G---HGGSIDSGPHPW---GKRKKMGQ-------------------------------
-------------------------------------------RTNYMLLLWFINF----
-M-L--LC---------FLI---------LCFLARK---RRD-ERKEPTVSPTH--EYEE
QNAKTLST-----EN------------------------------------MQDVS----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------LI
L--HALLL-------QHLTHMS--GS--------------------RQSDL

PF01562 // ENSGT00910000144019_0_Domain_1 (232, 429)

ERMNER--T
FLSVTVPVKIPTTSN----EDL--D-------PEY-ASYMITIEGKPYTIHLKQ-K----
------IFVPHDFRIYS--YNKEGFLNSV---TSHV------------------------
----KNLCFYQGYITGFPKS-TVTLSICS---GLR------GLLQFENISYGIEPLV-SA
-AGFEHMVYPININ-ST-AVPFLSHN----KM-Y-----IET--KG-L-S------DIQT
DI-------KAKSDHSKSFPLYLEIHVIVEKNLYEYLGS-GTTIITQKIAQVFGLVSRMF
SSFNVTIVL------SSLELWTDENKIS-TT-----GEVDAVLHRFLNWKDSYLV---LR
QLDMAYLLV----YRNT-----SD-YLGA------TF--PGKMCERK-YAGGV-AI---F
PKEISLEAFSVVIAQL-LGLSMGI-TYD-DV-----------SKCHCSS---AVCVMNPE
AVLISGVKVFSSCSYGAFESFILK--TKG--ECLQN--QP-H--LDPS-YR-----A-PI
CGNSVM

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 881)

ET--GEECDCGPP-T---VC-KD---NKCCNAATCRLQP-GAKCSLG------Q
CCS--GCQFIKKGTICRQQLDQDCDVPEYCNGSSAFCQPDLFVQDGRPCRS-RT-AFC--
---YKGKC-PSPDN-------------QC--RSIFGK---DV---ENGAF-----PCYEE
LNSKTDRSGSCGRTKT------------------G-YKLCQWKDLRCGKIICKYKSSKPF
FQT--Q---ATVIYVSV----N-GHVCITL----------------DY-RLHY-------
---------QKQDPIWVYDGSLCGFK---------QICLN--R-ECVDVSV-LGF--DCY
L--KCNG-HGIC-----NS--RKN-CHCDPGWL-PP----------D-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

PF01421 // ENSGT00910000144019_0_Domain_5 (643, 760)

MCHRK-YAAGI-AL---Y
PKMISLETFSVIIAQL-LGLNLGI-SYD-DI-----------KKCHCSG---AICIMNPD
AVHSSGVKTFSTCSIVDFENFISK--PGA--ECLQN--QP-R--LSP---IYR--A--PT
CGNFIKEA--NEECDCGPP-E---SC-EN---NRCCDAQSCRLKR-GAKCSSG------L
CCQ--DCEFKPQGTLCRNIADLECDIKEYCNGTSGFCPPDLHVLNGHLCRS-GT-SYC--
---YDGGC-RNADY-------------QC--RKIFGK---GS---KSAPF-----SCYEE
INIQRDRFGNCGSEN-------------------NNYKLCSWKDLLCGKLICTYPSQTPF
HIL--N---ASVIYAIV----R-RTICITL----------------DY-RLGP-------
---------KVKDPLLVENGTSCGPS---------MYCLN--Q-ECREARF-INSDCDYK
--VKCHG-HGVC-----NN--KNN-CHCDPGWL-PP----------NCKE----------
-RG-PGHGGSIDSGHLGK---SD-------------------------------------
--------------------IFFTGR--AYEDNT-------RKNWLLLGFYISLPF----
--LIIT---------TIII-VKRNEM------KRLC-------RTEELQSDEY-------
-TSEESNQS-------CSASEPSS------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MKMLL
L--LHCL-----------GVFL--------S-CS------GH-----I-Q-DEHP-QYHS
PPDVVIPVRITGTTR----

PF01562 // ENSGT00910000144019_0_Domain_1 (260, 429)

-GM--------TPPGW-LSYILPFGGQKHIIHIKV-K----
----K-LLFSKHLPVFT--YTDQGAILED---QPFV------------------------
----QNNCYYHGYVEGDPES-LVSLSTCFG--GF----Q--GILQINDFAYEIKPLA-FS
-TTFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YKMDSE-EK--QFSTMRSGFMQNE-I-----TCR-MEF-E-EI-----DNST
QK-------QSSYVGWWIHF

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 756)

RIVEIVVVIDNYLYIRYER-NDSKLLEDLYVIVNIVDSIL
DVIGVKVLL------FGLEIWTNKNLIV-VD------DVRKSVHLYCKWKSENITP-RMQ
-HDTSHLFT----TLGL-----RG-LSGI------GA--FRGMCTPH-RSCAIVTF----
MNKTL-GTFSIAVAHH-LGHNLGM-NH--DE-----------DTCRC--SQ-PRCIMHEG
NPP---ITKFSNCSYGDFWE---YTVERT--KCLLE--TV-H--TKDI---FN----VKR
CGNGVVEE--GEECDCGPL-K---HC-AK---DPCCLS-NCTLTD-GSTCAFG------L
CCK--DCKFLPSGKVCRKEVN-ECDLPEWCNGTSHKCPDDFYVEDGIPCKE---RGYC--
---YEKSC-HDRNE-------------QC--RRIFGA---GA---NTASE-----TCYKE
LNTLGDRVGHCGIK-------------------NATYIKCNISDVQCGRIQCENVTEIPN
MSD--HT---TVHWARF----N-DIMCWST----------------DY-HLGMK------
-------G---PDIGEVKDGTECGID---------HICIH---RHCVHITI-LNS--NCS
PA-FCNK-RGIC-----NN--KHH-CHCNYLWD-PP----------NCLI----------
-KG---YGGSVDSGPPPK---RKKKKKF--------------------------------
---------------------------------------------CYLCILLLI------
-VLFILLC---------C-LYR--------LCKKS-----KP-IKKQQDVQTPSA--KEE
EKIQRRPH-----E-----LPPQ----------SQPW--VMPSQSQPPVTPSQSHP----
-------QVMP-SQS-----------QPPVTPSQSQPR-V------MPSQSQPPV-----
---------MPSQSHPQL-----TPSQSQPPVTPSQRQP--QLMPSQSQPPVTPS-----
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLLLF-------LHLKGLQ--A---------------------GQ-----NPQK--T
TLQTTVP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

EKISSPDV----ETD--A-------EDH-MAYLITINETPHFIHLKK-Q----
------SFITPTAVVYT--YDRNDAQHSQ---PLSA------------------------
----LENCNYNGYVAGFPNS-IVTLTVCT---GL---R---GTIQFENVSYAIEPVE-TL
-SGFVHVIYENTNK-HA-V-IPDLGKN----Q-S----YGWL-DE--S-D------YQFR
SN-------MKKAGFTVLRQRFIMMDIIVDKKLFDYMGS-DTEVVLQKVIQIIGFVNTML
SKLKLTVLI------NSIEIWSKENRIH-LS-----KAVDDLLVQFSIWKH---E---YR
SQHVAYLLA----FEEH-----PA-STGA------LY--PGNLCKLE-YNAAV-AL---Y
PKGLSLESFSVIVLQL-LSIGMGL-TYD-T------------ENCHCTG---EVCLMTPK
AIYSGGVKDFSTCTLDDFKYLSTR--QDL--RCLQD--LP-L--ERK---PARRPR--RI
CGNGILEM--NEQCDCGTL-K---NC-TH---RKCCDPMSCRLKN-KAICGSG------E
CCN-QDCMVKMNDVICRKSVD-ECDFVEYCNGKDPYCVPNTYAR

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1067)

NGQYCDS-GE-AFC--
---FEGKC-QTVDK-------------QC--MSMLGK---YV---RGASF-----ACYEE
FNSRGDRFGNCIHH------------------------FCAFRNSLCGKLICTWPFKKLV
LKA--N---LSVAYAQI----R-DDLCVAM----------------YK-GGRIP--RP--
-TKTTYSNPSDRDETFVHDGTICGPD---------MFCLR--A-SCTETRF-HMDSSKCD
STRDCND-HGVC-----NN--LQH-CHCDLGYN-PP----------FCEE----------
-HK-G-QFGSIDDGHKYY---VEDG----K------------------------------
------------S---YKQ------Q---SHSNL-------KKNQLQLILYIALPL----
--LVMI---------S-AVVIKQSRL------SRVC----D---RERSESNSS-------
-TTEDSGSN-------TNVTSSGGSSSTD-----PP------I---TPNPERILYVFALK
------KH----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
C--LFLLL-------LGLIGLQ--T--------------------------DNNSAR--L
N

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 429)

VQITVPEKIQSISS----GG---I-------ESN-VSYNIVIEGKTYTVNLRH-K----
------SFLPNTFRVYG--YDRTGSMKPL---EEQI------------------------
----QNFCYYQGHIEGYPNS-MVIVSTCT---GLR------GLLQFENVSYGIEPLE-PS
-IGFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YPVKHK-NA-R-VSLYTE----DS-I-------E-SRE-V-T------YKIQ
SI-------EPL----ADFP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

RYIEMHVVVEKTLYSHLGS-DTAIVTQKVFQLVGLTNAIF
TSFNVTIIL------SSLELWIDENKIS-VT-----GDANELLHRFLKWKRSYLV---LR
PHDVALLLV----YREK-----SN-YIGA------TF--HGKICERQ-YGGAV-AL---H
PRAISLESLAVIIAQL-LSLSMGI-AYD-DI-----------NKCQCSG---TVCIMNPE
AIHFSGVKNFSNCSMEDFARFISK--PKS--QCLQN--QP-R--LDPS-YK-----D-AE
CGNQQVEQ--GEQCDCGSE-E---EC-AS---DACCEAGTCRLSA-DSECAEG------E
CCD--ACKFKAKGEECRATFD-ECDLPEYCNGSSASCQDNFYVQDGRSCSE-NQ-WFC--
---LEGKC-RSGLK-------------QC--EDTFGE---GA---EFGSS-----ECFAY
LNSKADQSGNCGSGPD------------------G-YQPCQPKDLQCGKLICKYHKEFLV
SVP--N---ASTIYTNV----Q-GDICIAL----------------EF-PHDY-------
---------QESPKMWVKDGTTCGKN---------KVCRN--K-ECVDAAY-LNY--DCT
DE-KCNN-KGTC-----NN--KKN-CHCNPTFL-PP----------NCTS----------
-VDGSWPGGSVDSGNFPP---APKPST--S------------------------------
------------VYVLGGTPITL--L---RFIKST-YH----SKPMRWPFFLLIPF----
--FIVL---------C-VLIATLVKVYFQ---RKKW----R---TEEYTSDEQ-------
-LESESEPK-------E-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------LF
F-----LL-------LVLTALS-------------------------FTDNHQYSQQ--I
FLSTTTPIKI-SPSS----GIL--E-------

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

PKY-VSYIITIEEKSYTLLLHQ-K----
------IFLPHDFRIYI--YNEEGILTSL---DPFF------------------------
----KNVCFYQGHVADFPKS-LLTLSTCS---GIR------GWLQFENFTYGIEPLE-SS
-LSFEHVI

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YRVKNN-NP-NVIFLYAE----KD-T-----SAI-SRR-S-V------YELP
EF-------DYQLDFFSSFSG

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

YLEMHVVVEKNLYEFLGS-DANIVTQKIVMVVGLISTMF
SSLNLTIVL------SSLEFWVDYNKID-TV-----GEPDEILKRFLNWKESYLV---LR
RHDVAYLLV----YRDT-----FK-YVGA------TF--QGKMCEKK-SAAGI-AM---Y
PRIFTLEALSVVIAQL-LAHSMGI-TYD-D------------ERCQCPS---AICIMTPQ
AVKSTGVKAFSTCSIKAFKDFVLK--KNP--ECLQN--RP-Q--LDPS-YR-----S-AV
CGNAVHEE--GEECDCGYA-K---EC-T-----ACCRAWLCKLVT-GKACAQG------E
CCE--NCQFRAKGTKCRNPIDSECDLPEYCNGSSAYCQADLHVLNGHQCRS-KT-SYC--
---IRGKC-LDPDD-------------QC--KDVFGP---DS---TFAPY-----ECFEE
LNSKADRTGHCGYGKE------------------E-FQVCPWKDLSCGKLLCEYKSTVPF
FNT--D---AVVIYVNV----R-DHTCITL----------------DY-EVRD-------
---------NNVDPMWVTDGVICGYK---------EICYK--R-QCVPVAA-LGY--NCP
GS-KCSF-HGVC-----NN--RGN-CHCDDGWL-PP----------DCST----------
-PIS-GIGASIDSGIHSK---SGDF-----------------------------------
------------------------------YFDIS-FKNI-----FGWLI----------
-----Y---------S-FN----LFPP---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
P--LFFIL-------AEFAMLL--A---------------------RL-----DSEG-

PF01562 // ENSGT00910000144019_0_Domain_1 (239, 429)

-I
CLHVTVPVKIEPRK-----SGV--S-------EGK-VIYVITIDGKPHSLHLKN-Y----
------SFLSQDFLVYT--YNETGYLYDD---PSHF------------------------
----MTHCHYRGYIDEYPNS-TVTLNICS---GL---R---GFLQFENISYRIEPLE-SS
-AKFEHIVYQVKNG-N-----PMLAEN----Y-S----HIWQ-TD--Q-L------DTGH
FN-------AQDKNHSQLLPQPLKLHIIVGKSLYDYMGS-DITVVTQKIFQIIGLVNTMF
AQLELTVVL------ASLELWSDKNHIS-TD-----GDANDILQRLLDWKQDYLT---LQ
SHEITHLLI----YRKH-----PK-YIGA------AS--PGELCNKS-YAASI-VM---Y
PEDIGLEGISVVITQL-IGFHMGL-SYD-NV-----------NNCSCSR---APCIMQQG
ALSSSGMKTFSNCSMHYYKHYASN--FVA--TCLGN--LS-N--VQVL-QQNQ-----PM
CGNGIVEA--NEECDCGND-T---EC-QF---KECCNYETCRLKA-SAKCGSG------P
CCA-ANCELSSAGTPCRKSVDPECDFTEYCDGSSSHCVPDSFAF

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1050)

NGHLCRL-GS-AYC--
---YNGRC-QALND-------------QC--VSLFGK---GS---QGASY-----ACFEK
VNSPREKLANCGFKN-------------------SYPFPCGQKDVLCGKLACFQPHKN-Y
KST--V---RSVVYSYV----H-DSVCLSI----------------PP-GLSVR------
--------SDGRDYAYVADGTVCGPQ---------MYCVN--R-TCKEVNL-TGN--DCN
ATKKCKG-NGIC-----NN--FGN-CQCFPDYR-PP----------DCNL----------
-QI-GSPGGSIDDGNILR---SD-I-----------------------------------
--------------------FFAR-K---HFSKH-------QDSWLILSFFIFLPF----
--IISL---------I-IGITKRDER------TVIP----Q---RDQQI-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MSVT---ASVRDSASFLSSLMKLHVV
LYEA------------------------RRVLQTWAPQMKNL-RLGLV-PGQ-SCVRVGM
M--LL-------------LGIIFLPSICCDMA-----------------------SVYYS
SYEIVIPKRLMVRGS------E--------

PF01562 // ENSGT00910000144019_0_Domain_1 (271, 429)

DSVEK-ATYLLLMQGQKHLVHLKV-K----
----R-SHFVNNFPVYS--YHN-GILGQE---SPFI------------------------
----SHDCHYEGYIEGVSGS-FVSVNTCA---GL----R--GILIKEEKSYSIEPMD-SS
-RRFEHVLYTMAHG-------ARVSCGVTSR-DSHVVSTSWQ-QG----------SRKPH
DL-------QAL-SYLWSHTKYVEMFVVVNNQRFQMWGS-NINETVQRVVDVIALANGFT
RGINTEVVL------AGMEIWTEGDLID-VA-----VDLQITLRNFNRWRQEMLFR-RAK
-HDVAHMIV----GHHP-----GQ-NTGQ------AF--LSGACSSG-FAAAVESF----
HHEDM-LLFAALMVHE-LGHNLGI-QH--DH-----------SACFCRE--KHFCLMHEN
ITK---ESGFSNCSSDYFHQFLRE--HKG--ACLFN--KP-R--PRGRKRR------DSA
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ED--TEECDCGS------AC-HL---DPCCDP-TCTLKE-HAECSHG------L
CCL--DCTFRRKGFLCRPTQD-ECDLPEYCDGSSAECPADSYKQDGTLCDR---IHYC--
---SGGQC-KNPDN-------------QC--VNIYGY---PA---RSAPE-----DCYIS
MNTRGDRFGNCGHPTE-D---------------QQTYVTCSDDNVFCGKLICTGVQSLPR
VKA--QH---TVIQVPH----D-NDWCWSM----------------DADNI---------
--------TDIPDNGNVHVGTSCAPN---------KVCMD---YSCVHHSI-LLY--DCR
PEESCHG-KGVC-----NN--LRH-CHCGSGFA-PP----------DCKN----------
-PG---NGGSVDSGPAGK---PSDEIISR---EENRNH----IVGHGNPQ----------
-------------------------R---GDMSNN--KN----KSLGK-LVYIVPL----
-LLLALFAG-----LI-ILASMGARKE-------------IL-QRSQGYTEGTP------
----------------EE-VAPEQ-------------------KLGKGQEEEAKNE----
--------------------------SS--------------------------------
-------NKANSGYTG--------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MGPC------G--------------------GC---PRA------
SSQITTPLRLPPNET--------------

PF01562 // ENSGT00910000144019_0_Domain_1 (270, 429)

-GLSDT-LSYILTVEGKPYTIHLKK-H----
------VFIRDDFRIYM--SDETGFSMSD---STHI------------------------
----RGDCYYHGSIEGVPSS-AVTLSACA---GLR------GLLQFHNASFGIEPLD-SS
-PTFEHFVYRMSSE-NT-A-GFLFAQS-CPR--A-AGEGLQE-DAG-I-Q------HIWL
FS-------FQPPSDAAQLPKYVEVYVVLDKALYNYLGS-DLNAVTQKMIQVFSFVNNIF
NPLNMTVVL------SSMELWMQQNRIP-TD-----GAADELLQQFLQWKRSHLA---LQ
PYDVTYLFV----YRDQ-----AD-FAVA------TS--PGTLCGSD-ASSAV-AV---L
QRAVTLESFSVLLAQL-LGRSLGM-GFD-DG-----------RGCCCPT---HTCVMESA
ALHISGTKAFSSCSTADLEQFLRR--DGG--RCLLH--GP-P--LQGS-SP----RRSPT
CGNGVVER--GEQCDCGSA-E---AC-SK---DKCC-AKGCVFKP-RAKCSSG------L
CCE--GCQFKAPNTPCRPSTDAQCDLPEFCNGSSASCPPDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1070)

DGHSCEH-GT-GYC--
---YRGHC-QSAEL-------------QC--QQLYGR---GS---RSAPV-----VCYEE
LNSQRDRFGHCGYHPR------------------HGYRACAWRNLRCGKLICTYPHSAPL
ETD--T---AAVIYARV----R-EQLCVSL----------------YL-LNAP-------
---------ASQDPLLVPAGTKCGSE---------MVCIN--S-TCHPHSV-LGY--DCN
SEIQCHG-HGVC-----NN--RRH-CHCHPGWK-PP----------DCRQ----------
-RG-SRLGGSIDSGVQLP---QRSS-----------------------------------
---------------------PQH-R---TQ-RNA------ERKGALLAACLLLPA----
--VPVA---------L-LLVLLRRELRV----RRFG----N---GE-R------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MVILTSIMHTIF
KPGFLNVYI------RVMFIWTRRELIR---F-TG--NPNHIIPQFGVWKSKAVHP-TIP
-HDTSVVFT----SHRI-----GNIECFA------S---FDGICNPN-WGAMFVYL----
MRYHL-FKGACVTAHT-LGHNMGM-HH--DS-----------QGCYCFRR--TNCVMAPV
PDL---NDMLSNCSYERLQNI-FN--RWD--PCLSA--PN-V--AYTN-YPYV----APR
CGDKIRNQ-

PF00200 // ENSGT00910000144019_0_Domain_7 (790, 880)

-REECDCGSL-K---DC-AS---DRCCET-SCTLSL-GSVCNTG------L
CCH--ECKYAVPGVVCRDVGG-ICDLPEYCDGKNETCPDDFYVQDGTPCSP---VSVC--
---IRGNC-SDRDM-------------QC--QALFGY---QV---KDGSP-----VCYKK
LNVKGDRFGNCGVILQRG---------------GSKPFRCEEDDVFCGMLHCSGVRRIPG
GGE--HTTFRSILVQEI----K-EETCFGY----------------DA-HHG--------
--------TELPEMGLVVDGATCGPG---------KYCLN---QNCTFYQD-LHF--ECD
LK-TCSY-KGVC-----NN--RNH-CHCVYGWQ-PP----------TCEL----------
-KG---KGGSVDSGPPPD---KQYRLSGRV------------------------------
-------------------------------------------IVNTNR-VLLLIF----
-ARYILFLVS----LL-FGGFS------K----AIE---FMD-EKVLKNTEPD-E-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWA-RAH-STGDLWL
P--LLGLL---------------LSAVCCSH

PF01562 // ENSGT00910000144019_0_Domain_1 (212, 428)

TLP------GW-----R-F---------T
FSEVVIPRKVSHRVG-----GT--------ERQGQ-LSYKIYFRGQRHVVHMKI-K----
----K-NLLPRQFPVIT--DNDQGAMQED---YPFV------------------------
----PRDCYYYCYLEGVPGS-MGTLDTCYG--GL----H--GMLQVDDFTYEIKPLE-TS
-SKFEHVVSLLVSQ-RR--LSGLERCKIEEH-------NTDQEYEE--------TILAGT
PR-------ATPVYLWWPHKKYFKIHYTTSKSLIELD-T-NLTHVIESVMILNNILHTIY
KPTLLDVYI------RVLCIWDKRDKVD---L-YEEQDIQNIMTDFALWKYWGWYN-DIP
-HDTSMLLT----GDRI-----GGASYYG------Q---PNGVCNPK-WGVAYVYM----
TRYHV-FLAAAVAAHT-LGHNLGV-DH--DT-----------PGCQCFRR--KHCVMAPE
PGL---LDMMSNCTYDKIHHK-VT--IWD--PCLSR--PN-V--RYTN-FPYI----AAR
CGDLFVDQ--GEECDCGSL-K---QC-ST---NKCCKS-DCILTP-GSDCNGG------T
CCV--DCKYALPGWLCRDRLG-ICDLPEYCDGRSHNCPNDFYTQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGTPCSP---LAVC--
---MRGNC-SDRDL-------------QC--QSLFGH---QI---KDGAP-----ACYQK
LNVLGDRFGNCGVKRIQG---------------GGKPVKCEERNVFCGLLHCRDVKEIPG
GGE--HTVFRHIIVRDV----K-EELCFGY----------------DA-HHG--------
--------MNLPEMGLVVDGAMCGPG---------RHHWC---LSSFRRDD-VRR--G--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGPAWV-QDP-LTGALWL
P--VLWAL---------------LSQVYCFHDPP------GW-----R-F---------T
SSEIV

PF01562 // ENSGT00910000144019_0_Domain_1 (246, 428)

IPRKVPHKRG-----GV--------EMPDQ-LSYSMRFRGQRHVIHMKL-K----
----K-NMMPRHLPVFT--DNDQGAMQEN---YPFV------------------------
----PRDCYYDCYLEGVPGS-VATLDTCRG--GL----H--GMLQVDDLTYEIKPLE-AS
-SKFEHV

ENSGT00910000144019_0_Linker_1_5 (428, 513)

VSLLVSE-ER--PGEASRCKTEGE-------EIDQESEK--------VKLAET
PR-------AGHVYLWRHHRKNLKIHYTVTRG

PF01421 // ENSGT00910000144019_0_Domain_5 (513, 743)

LFMRN-P-NVSHIIENVVIINSIIHTIF
KPVYLNVYI------RVLCIWNQKDAVL---F-SASRPGHVAVELFGVWKYHNLYS-EIS
-HDTSVVFT----SNRL-----GNSECYA------S---FDGICNPN-WGAMFVYI----
MRYHL-FRGACVTAHA-LGHNMGL-TH--DS-----------VGCYCFRR--TNCLMAPV
PDL---NDMMSNCSYEIIQRK-FN--QWD--PCLSA--PN-V--PYTN-FPYV----APH
FGDKIKNQ--REECDCGSL-K---DC-AS---DRCCET-SCTLSL-GSVCNTG------L
CCH--KCKYAAPGVVCRDLGG-ICDLPEYCDGKKEECPNDVYIQDGTPCSA---VSVC--
---IRGNC-SDRDM-------------QC--QALFGY---QV---KDGSP-----ACYQK
LNRIGNRFGNCGVILQRG---------------GSRPFPCEEDDVFCGMLHCSSVSHIPS
GGE--HTTFCNILVHDI----K-EEKCFGY----------------EA-HQG--------
--------TDLPEMGLVVDGATCGPG---------SYCLK---RNCTFYQD-LHF--ECD
LK-TCNY-KGVC-----NN--KKH-CHCLHEWQ-PP----------TCEL----------
-RG---KGGSIDSGPPPD---KQYRIAGSI------------------------------
-------------------------------------------LVNTNR-ALVLIC----
-IHYILFVVL----LL-FGGFS------Q----GRE---RER-AHTME------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------M

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

F
L--LVALL-------AELGGLH--A---------------------LQ-----DSEG--I
FLYVTVPQKMRSNE-----SED--S-------EKQ-VTYIITIDKKPYTLHLRK-H----
------SFVSQNFLVYT--YNETGSLHSE---SSYF------------------------
----KMHCHYQGYVADFPNS-VVTLSICS---GL---R---GFLQFENISYGIEPLE-SS
-ARFEHII

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQVKND-NP-D-MPMLAEN----Y-S----NIWQ-RD--Q-P------YKVH
LN-------SQEKTLSELLP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

QYLEMHIIVDKALHDYMGS-ETMAVMQKMIQLIGLVNTMF
SQFKLTVIL------SSLELWSDKNQIS-TN-----GDADDLLQRFLTWKQDYLI---LR
PHDVTFLLI----YRKQ-----PK-YVGA------TF--PGTICNKS-CDAGMLXX---Y
PGAITLEGFSVIIAQL-LGLKIGL-TYD-DI-----------RKCSCPS---AMCIMNHE
AVVSSGVKMFSNCSMRDYRYFVST--FEG--QCLQN--FS-K--LKPL-YQNQ-----SV
CGNGILEP--QEECDCDSE-Q---DC-QF---KDCCDYNTCKLKG-SVKCGSG------S
CCT-SKCEISAAGTPCRKSVDQECDFTEYCNGTSSDCIPDTYAMNGQLCRL-GT-AYC--
---YNGRC-QTTDN-------------QC--AKIFGK---GA---QGAPF-----ACFEE
VNSLRNSLGNCGFKN-------------------SQPLPCEQKDVLCGKLACVWPHNTTY
KSD--V---RSAVYSST----Q-GHVCIT------------------I-GSSVR------
--------LGGRDYAYVADGTVCGPQ---------MYCIN--K-TCKEVPL-MGY--N

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CN
ATTKCRG-NGIC-----NN--LGN-CHCFPGYR-PP----------DCEL----------
-QI-GSPGGSIDDGNDHK---SV-T-----------------------------------
--------------------IFTK-K---GYNAH-------Q-NWLILSFYIVLPF----
--FIIF---------T-IMIMKRNEI------RKSC----N---KESAEYE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MSVL---ALLKDSANILLYLWKSQVA
LEEV------------------------KIKFQTWAPQKWNL-RMGLV-PGP-SCIRLEI
---LL-------------LLVIFVPSMQCHLG-----------------------SIYYS
FYEIIIPKRLTVQGG------D--------SS

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

VEG-LSYLLFMQGQRHLVHLKV-K----
----R-SHFVNNFPVYS--YHN-GILGQE---SPFI------------------------
----SHDCHYEGYIEGVSGS-FVSVNTCA---GL----R--GILIKEEKSYSIEPMD-SS
-RRFEHVL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YTMAHE-------ARVSCGVTSR-DSHVVSTSWQ-QG----------SRKPP
DL-------QAL-SYLWSHT

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYVEMFVVVNNQRFQMWGS-NINETVQRVVDVIALADSFT
RGINTEVVL------TGMEIWTEGDLID-VA-----VDLQITLRNFNRWRQEMLFR-RAK
-HDVAHMIV----GHHP-----GQ-NTGQ------AF--LSGACSSG-FAAAVESF----
HHEDV-LLFAALMVHE-LGHNLGI-QH--DH-----------SACFCRE--KHFCLMHEN
ITK---ESGFSNCSSDYFHQFLRE--HKG--ACLFN--KP-R--PRGRKRR------DSA
CGNGVVED--TEECDCGS------AC-HL---DPCCDP-TCTLKE-HAECSHG------L
CCL--DCTFRRKGFLCRPTQD-ECDLPEYCDGSSAECPADSYKQDGTLCDR---IHYC--
---SGGQC-KNPDN-------------QC--VNIYGY---PA---RSAPE-----DCYIS
MNTRGDRFGNCGHPTE-D---------------QQTYVTCSDDNVFCGKLICTGVQSLPR
VKA--QH---TVIQVPH----D-NDWCWSM----------------DADNI---------
--------TDTPDNGNVHVGTSCAPN---------KVCMD---YSCVHHSI-LLY--DCR
PEESCHG-KGVC-----NN--LRH-CHCESGFA-PP----------DCKN----------
-PG---NGGSVDSGPPGM---QVTN---N---SESGSE----SIARGQSL----------
-------------------------R---QDLD------------YKL-VVLLVPL----
-FLVLLLCS-----LL-TISYLCSEVQT-----------AVA-EVEEASTETTL------
ESELTSADLV---PIAEEILPPGEEAPPPGAEAPQPG----EETLPPGEEAPQPGE----
--------------------------ET--------------------------------
-------L--PPGEAPPAAEAPPAAEA-PSPE-----AAP----PPGAAPPPEAAPAPEA
------AVPAPEAAAPPQAPPPE--------------------------AAPPPEAPPAQ
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------FQQ--S
F

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 429)

VEITVPEKIVSNSS---DSKS--E-------YEE-ISYVISVERKLYTLQLKQ-R----
------LFIPEDFIVYM--YNREGALYYK---SDII------------------------
----LKHCNYQGHVAGSPKS-VVTLHTCS---GL----R--GLLQFENVTYGIEPLQ-NS
-GGFQHLIYRLKSE-NT-D-LAVLAKK----N-T----HMKS-E-D-L-E----HKLGSL
ID-----SR---SVSPKLLPQYVEIHIVLDKSLYDYMGS-DTESATYKVIQILGLLNAIY
SQLKITIVL------SSLEFWTYENKIS-TT-----GEPDEILQRFLEWKNSYLV---LR
PHDMAYLFL----YRKN-----PM-TVGA------TF--PGKMCILH-YAAGI-VL---Y
PKGITVEAFSVIIAQL-LGISLGI-KYD-D------------KRCHCFK---STCIMRPE
AVFSSGIKIFSQCSLNDFQNFISK--TGA--TCLKN--QP-N--LKFS-ARGN--T--GV
CGNYIVEE--GETCDCGPPSV---SC-GT---NKCCDPNHCTKNY-YAHCLSG------V
CCK-ADCKFND-GGMCRPSYDLECDFPEICNGSSESCPIDLKAL

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1096)

DGSSCSE-FS-NLC--
---FGGSC-QDPNK-------------QC--QRLFGR---AS---KNGPF-----ACYEE
INSQQDRFGNCGRRAE------------------NKFVFCNWRNLLCGKLICTYPYRKPY
IRE--N---VAVIYSYV----L-NTVCISL----------------DH-KFKK-------
---------NVRDPMLISNGNPCDGK---------KFCFN--S-QCVFLNR-IIDAAKSC
STVQCNS-HGAC----TDN--KGV-CICESDYN-PP----------NCLM----------
-KK-SRSIGNFLP---WK---SG-------------------------------------
--------------------TTIT-R--SAK-HS-------KKNWLILSFYLFLPV----
--IFIV---------TII------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QTT-RQL-F-QKS--INFTLK
QG-------DIHYGGWWLHAFFFELVMVVDHNRYVFRDN-NATLAQEDVLIVLSDVSTFY
LQLGLQITL------TGIEVWTTENPIT--G-----DTIENLLTSFCSWKKGALND-RIV
-HDGAGLIV----KVDE-----SL-GTHS------AE--FGRVCNNE-NNGVIVNF----
VDLNY-TLLAMRLTYV-LGKLLNV-ED--DN---------SEEFCVCRSG--DRCLMNAT
I-D--VSVHFSNCSFFYFYRFTIK----K--PCLQN--QP-E--IQIS-SVKT----KQH
CGNGLVEE--GEQCDCGSW-K---LC-YR---DACCWA-NCTLRM-GADCAHG------D
CCK--NCQFIPQGTMCREGDD-DCDLPEWCNGSSHACPDDVYKQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

NGSPCRV--I-GYC--
---FENMC-NTRDD-------------QC--KDIFGN---ET---KNAEN-----LCYTT
VNTRGDRFGHCSVQ-------------------GTTYTGCSLANSLCGRIQCQNVKRLPP
MAE--HT---TIHWYYM----K-DIVCVGT----------------DY-HLG--------
--------IISHDMGLVREGTECGED---------LMCIG---KECVPVSH-FEQ--SCK
E-ETCNL-RGIC-----NN--RHH-CHCTYDWD-PP----------FCLK----------
-EG---SGGSIDSGPPPQ---KVK------------------------------------
----------------------------------R--VK----KVKHGFLIWIIIVLL-I
LLLLILLL------FL-LRTHSYVQL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MTVGGT-L---IYTRITL
L--LLSL-----------GVSL--------S-IH------GL-----S

PF01562 // ENSGT00910000144019_0_Domain_1 (229, 429)

-Q-ARPS-QHFS
SPEVVIPLKVTSRGR-----GA--------KAPGW-LSYRLRIGGQRHIVHMRV-K----
----R-LLVSTHLPVFT--YTEQHGLQED---HPFV------------------------
----PDDCYYHGYVEGVPES-LVALSTCSG--GF----Q--GILQIYSLPYEIKPIG-HS
-TTFEHLLYQIVHD-NT--ESSYLKCGLTEEA-I-----EHQ-LEL-Q-AS-----YNST
LK-------QSSISGWWTHWRFVELAVVVDHVRFLYSQS-NVSVVQYEIFHVINIVDEFY
HPIQVDITL------TGIEIWNKGNPIS-TS-----KALEELLSDFAIWKHSHLDP-HLQ
-YDTVHLFI----NEKY-----NA-TVGM------AY--IEGICDPP-FNCAVSVF----
ESQDL-FLCALTMAHE-LGHNLGM-RH--DD-----------QWCAC--EV-EWCLMYTY
RRN---TTKFSNCSYAQYYD---TTRNPG--MCIHS--PP-Y--TGYV---SG----LKF
CGNRVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

EE--GEECDCGSV-H---QC-ER---DPCCLL-DCALRP-GAACASG------S
CCK--DCKFLPPGTLCRQQVS-ECDLPEWCNGTSHECPDDVYIQDGTPCMG---GASC--
---YAKTC-NNPDV-------------QC--KEIFGR---EA---RSASE-----ICYSE
VNTQGNRFGHCGIV-------------------ETTYVKCMAPDIMCGRIQCENVHKVPN
LKE--HS---TVHQYHF----N-DTTCWGT----------------DY-HLGMS------
-------I---PDIGEVKDGTVCAPG---------KICIG---RKCASVNP-VPQ--NCE
P-LHCSL-RGVC-----NN--RQH-CHCRHGWA-PP----------NCSY----------
-EG---HGGSVDSGPPPT---NRREGLSVV-G----------------------------
-------------------------------------------NVGYTSVLLVIPL----
-IAIILYC---------LFVL----------CKKEKD-RNKE-VEITEEAEST-----E-
--TEEY------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MSMV---ASLRHSASILPLLWKNRGA
LKEG------------------------KITFQTWAPRKRDF-RPGPV-PES-SYVRL

PF01562 // ENSGT00910000144019_0_Domain_1 (179, 429)

GI
V--LL--------------LVIFLPSLYCNLG-----------------------SVDYT
FYEIVIPKKLTVHER------D--------TPVKD-TSYTLLMQGQKQVIHLKV-K----
----R-DYFVKNFPVFS--YRN-GVLGQG---MPFI------------------------
----SHDCHYEGYIEGVPGS-FVSLNTCS---GL----R--GFLIKEGKPYGIEPMD-TS
-KRFEHVL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YTVAHQ-------ARVSCSVTSK-GSQAVSTSRQ-RG----------SRKPR
SL-------QAL-SSFWSHT

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYVEMFVVVNNQRFQMWGS-NVNETVQRVMDITALANIFT
RGINTEVVL------AGMEIWTERDLIE-VP-----ADLRVTLRNFNSWRQEKLFH-RVK
-HDVAHMIV----GHPP-----EE-DVGQ------AF--LNGACSRG-FAAAVESF----
HHEDV-LLFAALMVHE-LGHNLGI-QH--DH-----------SACICND--KRFCLMHEN
ITK---ESGFSNCSSDHFYQFLQE--HKG--ACLFN--KP-R--PKGRLRR------QAT
CGNGVLEQ--NEECDCGP------DC-GG---NPCCDQ-TCRLKE-HAQCSEG------L
CCF--NCRLRHKGFMCRSASG-ECDLPEYCDGTSGVCPRDHYKQDGTACDI---IHYC--
---FMGRC-KNPDT-------------QC--MDIYGF---PA---RSAPE-----DCYIS
MNTRGDRFGNCGFGAS-P---------------RSKYVKCSDENIFCGKLVCTNIRQIPA
IKR--HH---TVIQVPH----E-KGFCWSM----------------DAYNL---------
--------TDIPDDGDVDSGTLCAPY---------KVCMN---YSCIHHAV-LRY--D

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CE
PKEMCNG-RGVC-----ND--LRH-CHCEEGYA-PP----------DCKA----------
-PG---NGGSVDSGTPSK---SPE-------------E----NLSAGGSV----------
-------------------------I---PTKRKT--EM----NVLG-KIIFILPA----
-LLLLLLLI-----LI-ISISLNAGIE-------------SI-ETPGGSSE---------
-ETSESTETT--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------QISLSKG-LSLAG-Q---VTMKALL
L--VLSL-----------WAG--LV

PF01562 // ENSGT00910000144019_0_Domain_1 (206, 428)

PAQGSQGHP------SW-----R-Y---------I
SSEVVIPRKEVHHGK-----GV--------QMPGW-LSYSLHFGGKRHIIHMRH-K----
----K-LFWSRHLLMMT--QDDQGALQMD---YPFI------------------------
----PPDCYYVGYLEEIPLS-MVTVDTCYG--GL----E--GIMKLDDLAYEIKPLS-NS
-QRFEHIVSQIVAD-IN-ATGPTYKVGYKQD--M------DT-LFP---Q----EIAIPG
SR--------ISNRIFSSHKSMIKGFAQSSNSVYRLYN--NVTTCAKFLIDMVSLMDSIY
KGLDIKFHL------TAILIFDVRDPVN-MN------DYRLPSGPYHRFHETYLFR-IIN
-PSSSFVVV----KEGP-----QDYQNEP------A---AFGLCSPR--CLHMVGH----
LGRHY-LLLAVITSQY-CARSIGI-PF--DN-----------PECSCQRR--SSCIMYRY
PVL---TDSFSNCSFAHLQNILSI--N-K--HCLFD--EE-V--IFFN-----TSLTHIR
CGNSIV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

EE--KEQCDCGSI-K---QC-AS---NPCCGN-NCKLET-TFLCDKG------L
CCT--NCTFSAVGTLCRPIRN-ICDLPEYCKGGSSECPDNFYMQDGTPCTE---EGYC--
---YRGNC-TDRTM-------------HC--KEIFGA---NT---VEGPG-----ACY-R
INKKGHRFGHCKREFA-----------------ARHFIRCGDQDVKCGRLQCTNVTHLPQ
LQE--H---VGFHQSKI----S-GVWCWGL----------------DT-HRS--------
--------TGTTDVGHVRPGTPCGHG---------KFCNN---SACIGTIGEINY--DCF
PE-KCHR-RGIC-----NN--NRN-CHCHVGWD-PP----------FCEL----------
-RG---KGGSIDSGHPPR---RMRSIRQSH------------------------------
---------------------------------------------ESV-IYLRVVF----
-GRIYALIAS----FL-IGVATNV------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------M

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

F
R--SVVLL-------AGLGALL--RA--------------------SP-----DFQN--S
SLQIVVPEKIQENTS--NNSEV--E-------NKQ-ISYIIPINEKPYTVHLKQ-R----
------FFLAENFMVYL--YKQ-GSVNSH---SSNI------------------------
----QTQCYYEGYVEGYPNS-IVILSTCS---GL---RR--GLLQLENVSYGIEPLE-VE
-VEFQHLL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YKLKNE-NN-V-FVVHAEN----S-R----GLEQ-K-P-M-D------YSIS
IS-----EKSESA-VQDLIP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

LYLEMHIVVDKVLYDYLGS-DSMLATDKVIEIIGLVNSVF
AQLNVTIVL------SSLELWSDKNKIS-TV-----GEADELLQRFLEWKKSYLT---LR
PHDIAYLFM----YRDY-----PN-DVGA------TF--PGKMCTAQ-YSAGI-AL---Y
SEEITLEAFSVIVTQM-VGLSLGI-SYD-DP-----------KKCQCSG---AICVMNAE
AVQSSGVKTFSNCSLSDFKSFILN--MGA--KCLQN--KP-Q--MQV----RQ--K--AV
CGNGKVET--PEVCDCGTE-D---QC-GK---DSCCDPKLCVLKA-GSACDTG------L
CCS--NCQIQQAGSPCRPSVHPECDLPELCNGSSSACPTDVMIINGHSCKN--K-YIC--
---YNGEQLSPLDS-------------SCDGGSLVGNTLTGS---KNAPF-----ACYEE
IQSQLDRFGNCGKER-------------------GQYKFCQWRNLICGRLICTYPTLTPY
IQR--N---VAVLYAYV----R-NVICITL----------------DY-SLHG-------
---------SNVDPLVVNDGSECDSE---------RVCIN--R-QCVESRF-LKKDSLN

PF07974 // ENSGT00910000144019_0_Domain_10 (1140, 1188)

C
S-AKCSG-HGVC-----TS--ELK-CHCDSGWT-GQ----------DCNT----------
-QS---RGFGTY--WVCP---FK-------------------------------------
--------------------LIME-R--DAW-KS-------AKNRWLLGFYITLPV----
--LIIV---------IITA-ITLNYL------KKRF----S--KEEESRSSK--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MLSLTWGM-KLVER-S---VVPRVLL
L--LFAL-----------WLLL-LVPVRCSEGHP------TW-----R-Y---------

PF01562 // ENSGT00910000144019_0_Domain_1 (240, 428)

I
SSEVVIPRKEIYHSK-----GI--------QTQGR-LSYSLRFRGQRHIIHLRR-K----
----T-LIWPRHLLLTT--QDDQGALQMD---YPFF------------------------
----PVDCYYFGYLEGIPQS-MVTVNTCYG--GL----E--GIMMLDDLAYEIKPLN-DS
-QGFEHI

ENSGT00910000144019_0_Linker_1_5 (428, 513)

VSQIVSE-PD-VTGPTNTWKRLNLN-T------GP-PLS---R-T--EYANGT
PR--------MSSKNYASHPAAIKGQFQATNS

PF01421 // ENSGT00910000144019_0_Domain_5 (513, 755)

IYKESN--NIDTAARYLFELLSITDSFL
ITIHMRYYA------ILLTVFTESDPFA--L------EYTVPGGSIYNYYVSNFFN-RLR
-PDASTVLN----KDGP-----SDNDFHP------V---EQSLCTPA--GLTIVGQ----
HRRSF-LALSVMITNR-IAMSLGI-KAD-DE-----------TYCICHRR--TTCIMYKN
PEI---TDAFSNCSLVQINQILNT-PGTM--SCLFY--DH-H--VYHN-----ITKTYRF
CGNFKIDI--GEQCDCGSH-K---AC-YA---DPCCGS-NCKLTA-GSICDKE------L
CCA--NCTYSPSGTLCRPIQN-ICDLPEYCSGNNIFCPADTYLQDGTPCSE---EGYC--
---YKGNC-TDRSV-------------QC--KEIFGV---NA---KGANI-----KCY-D
INKQRFRFGHCTRAQE-----------------SLMFNACSDHDKLCGRLQCTNVTNLPF
LQE--H---VSFHQSVI----S-GFTCFGL----------------DE-HRG--------
--------TETTDAGLVKHGTPCSQT---------NFCDR---GACNGSLSRLDY--DCT
PE-KCNF-RGVC-----NN--HRH-CHCHLGWK-PP----------LCRE----------
-EG---PSGSTDSGSPPK---ERRTIKQSR------------------------------
---------------------------------------------EPL-LYLRMLF----
-GRLYLFIVS----LL-FGVATRAGVIK------V-----FK-FEDLQAALRAAQ-----
AKAT--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------AV-Q---VTMKALL
L--LLAV-----------

PF01562 // ENSGT00910000144019_0_Domain_1 (199, 428)

WAG--LAPVQCSQGRP------SW-----R-Y---------I
SSEVVIPRKELYHGK-----GV--------RMPGW-LSYSLHFGDKRHIIHMRR-K----
----K-LFWSRHLMMMT--QDDQGALQMD---YPFI------------------------
----PPDCYYLGYLEEIPLS-MVTVDTCYG--GL----E--GILKMDDLAYEIKPLS-NS
-QRFEHIVSQIVTD-TN-VMGPTYQLGHKEI--M------DP-LYS---Q----ANSSVV
PR--------ISSKMYSSHNGNMKGLALSSNSMYTVFN--NMSKCAQFLIKICSLIDTFL
QGIDINYYI------GSIIIYNQRDPVF-MN------NYNAHFSPYVRHYQFAVYR-FII
-PHSSIIVI----KDGP-----NDLNYEP------A---IYGICNNR--NLVMLGY----
LGRHL-LILSIAGAQK-VARNLGL-YY--DE-----------STCTCQRR--SLCIMHRK
PSL---TDSFSNCSYTHVQHIVGG--GKG--ECLFS--TR-L--LYLN-----KSLTHDR
CGNRIV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

DQ--GEECDCGSF-K---QC-YN---NPCCTN-ACRFTS-GSKCNTG------R
CCT--NCTYSPPGTLCRPIQN-ICDLPEYCRGKSSACPDDFYMQDGTPCTE---VGYC--
---YLGNC-TDRTV-------------HC--QEIFGK---NA---VKGSD-----ACY-I
INRRGNRYGHCSRKEE-----------------LMKHKACAIEDIYCGRLQCGNVTHLPH
LQE--H---VGFHQSLI----S-GFWCFGL----------------DS-HRS--------
--------TGANDVGHVRTGTPCDRE---------KICID---GSCIARDVQLNY--DCL
PE-KCSH-RGIC-----NN--NKN-CHCHIGWD-PP----------HCID----------
-RG---AGGSTDSGPPPR---KMRSVRQSN------------------------------
---------------------------------------------ESL-IYLRVVF----
-GRIYALIAV----FL-FGVATNVRTIK------T-----VK-VVEEKADEVS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--VLLIL-------SGLGQLT--SA--------------------GR-----HSVT--S
LLQITVPQKIVK

PF01562 // ENSGT00910000144019_0_Domain_1 (253, 429)

DTK---DGRA--S-------DTN-VTYAIKINRKTFTLHLEK-Q----
------SFLDSGFLVYS--YNKSGILHPD---SSFI------------------------
----KGHCFYQGYAKEIPNS-VVTVSTCS---GL---R---GLLQLENISYGIEPLE-SS
-ATYEHMI

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YQIKDN-KS-D-FPPIVKN----H-S----TTQF-PD--Q-P------FKIL
VK-------SEKKSDV-LLKR

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 759)

ILKIQVIIDKALYDYMGS-EVALASEKVVYIFSLINNMF
SQLKMTIML------TSLELWSDKNKIL-TN-----GDANEMLQKFVSWKEKKLF---QR
SHDMAYLLI----YRDH-----PN-YIGA------TY--HGMACNPK-FAAGI-AL---Y
PKMISLEAFSVILAQL-IGINLGL-TYKSDI-----------YNCDCPG---NICIMNPE
AIRSRGVKFFSSCSIDEFKSTVSQ--PEF--ECLQN--QI-I--SKVV-SQGQV----AS
CGNGVLDA--GEQCDCGDA-E---RC-SH---KKCCNPKTCELIT-NAECGTG------I
CCDKETCQIAERGTLCRRSTD-VCDFPEYCNGITEFCVPDVKSADLETCNN-KT-AFC--
---FQGLC-RDPDK-------------QC--AELFGK---FA---RGGSD-----LCSQH
VNGQTDNFGNCRGR------------------------FCRYRDLGCGKIVCTWMRSEVV
PFK--N---FDTQYTYY----K-GLLCVSA----------------QL-RNSTPV-----
--------NLPEDFTYTWDGTMCGPK---------QFCMR--G-SCTNISD-YVQRPNCN
STARCRG-HGVC-----NT--QLN-CHCDAGYA-PP----------ACEP----------
-SP-SSPGGSIDDGFWIL---EDE-DVK--------------------------------
------------------YTKLLL-K---RPRAS-------QKKGLLISFYIFLPL----
--LILI---------A-LITLKCNKK------KIFQ----D---KEGTVSEES-------
-LSEASSSK-------SNNLTFK-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------LRTPL
L-

PF01562 // ENSGT00910000144019_0_Domain_1 (183, 429)

-LLGL-----------WVV--LAPTQCSQGRP------SW-----R-Y---------I
SSEVVIPTKELHHSK-----AV--------RAAGW-LSYSLRFGGQRHVLHMRR-K----
----R-LFWPGQLVMMT--QDDQGALQVD---YPFV------------------------
----PLDCYYLGYLEDVPLS-MVTVDTCYG--GL----E--GILKVDDLAYEIKPLK-DS
-QRFEHII

ENSGT00910000144019_0_Linker_1_5 (429, 511)

SQIVAD-TN-AIGPMSSLGHKAE--R------YP-LFS---D----QNPSAA
SR--------VSSKIYASHIGAMKGCLMSA

PF01421 // ENSGT00910000144019_0_Domain_5 (511, 758)

HSIYTLYN--NVSQCAQYLVHLGSMIDAMF
RSLNMRYYI------GLLIIYNVREPTD-MN------NYKVPGGPFANDYARNIHK-HYL
-PYPGIIVK----RDGP-----HEVNFKP------E---LYTLCGNR--NLIFLGQ----
LSRHY-LLLSIIASNQ-IGTTFGL-WL--DT-----------VECVCQRR--ATCIMYRY
PVL---TDSFSNCSFQHTAHVLNN--NIQ--LCLFQERGQ-L--VYSN-----SSLTTIR
CGNSVVEN--EEQCDCGTF-K---QC-YS---NTCCES-DCRFSP-GSICNRE------T
CCT--NCTQAPAGTLCRPIQN-ICDLPEYCMGKDTNCPSDFYLQDGTPCTE---DGYC--
---YEGNC-TDRSM-------------HC--KEIFGE---GA---LSAPD-----VCY-S
INKKGHRFGHCKVTIG------------------FAPQRCADADVMCGRLQCVNVTHLPR
LQE--H---VGFHHSII----G-ESLCFGV----------------GA-HRG--------
--------TESTDVGAVRSGTPCGGG---------KFCLK---GFCNATLAAIDY--NCP
PS-KCNY-RGVC-----NN--NRN-CHCHVGWD-PP----------LCIN----------
-SG---AGGSVDSGPAPR---RRRSVRAGG------------------------------
---------------------------------------------MSL-VYLRVVF----
-GRSLALIAA----LL-FGVAMNDQAIR------P-----AS-VPGGPGPSS--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----M

PF01562 // ENSGT00910000144019_0_Domain_1 (367, 429)

HCHYQGYVADIPNS-LATLSICS---GL---R---GFLQFGNITFGIEPLE-SS
-ASFEHII

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YQVKND-DP-D-IPLLAEN----Y-S----NSWQ-KN--Q-P------YKDN
LS-------SQEPTLSELLP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

QYLEIHITVEKGLYDYMGS-EMMAVTQKIIQIIGLVNTMF
TQFKLTVML------SSLELWSDKNKIS-TN-----GDADDLLQRFFIWKRDYLI---LR
PHDIAFLLI----YRKH-----PT-YFGA------TF--PGTICNNS-YEVDI-AM---Y
SDAITLEGFSVIIAQL-LGLKMGL-TYD-DI-----------NTCSCPR---ATCIMDRK
AVGSSGIKFFSNCSMHDYRYFVSK--FET--KCLQN--FP-N--LQPL-YQNQ-----SV
CGNGILEP--NEECDCGSQ-E---EC-QF---KKCCDFNTCKLKG-SAKCGSG------P
CCT-SNCEISVAGTPCRKIIDQECDFTEYCNGTSSNCVPDTYASNGMLCRL-GT-AYC--
---YNGRC-QTTDN-------------QC--AQIFGE---GA---QGAPF-----ACFKE
INSLHDKFGNCGFKN-------------------SQPLPCDQKDVLCGKLACVWPHKNTY
KND--V---RSAVYSYI----Q-GHACISM----------------TT-GLSVR------
--------SDGRDYAYVADGTVCGAQ---------MYCIN--K-TCRKVHL-MGY--NCN
AIAKCRG-NGIC-----NN--LGN-CHCFPGYR-PP----------YCEF----------
-QI-GSPGGSIDDGNVKK---SD-I-----------------------------------
--------------------IFIK-E---DYNAQ-------QNNWLILSFYIVLPF----
--IIIF---------T-IMIIKRNEM------RKSC----K---RENAEYEGN-------
-SAIAPE-N-------Y--------DVA------Y-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MNMIDA-V---LYTRVLF
L--LDWF-----------GVSW--------S-FS------RL-----T-Q-TEHP-QYHS
PPDVVIPLKVTDTTG-----KM--------

PF01562 // ENSGT00910000144019_0_Domain_1 (271, 429)

RPPGW-VSYSMNFGGQRHIVHIKA-K----
----K-LLLYKHLPVFT--YTDQGALLED---HPFI------------------------
----QNGCYYHGYVEGDPES-MVALSNCFG--GF----R--GMLEINNIAYEIMPMM-FS
-TTFEHLVYKMDNE-ET--ESLTRRSGFMKDK-I-----TCQ-IEF-Q-EV-----NNFT
LK-------QSSYEGWWTHYRIIEIVVVIDNYLYVHYTG-NVSKIMMDLFIVSNIVDSIY
SVLDIKVLM------FGLELWTNKNPIV-VD------DVRKSLDLYCKWKTENILP-RLK
-HDTTHLFI----YRHL-----RG-LSGL------GS--TKGMCNPL-RSCAIVTF----
INRTL-TLSAIAVAHH-LGHNLGM-PH--DD---------P-STCKC--LP-RKCIMHED
NPP---TPKFSNCSYSYFWW---FTLERA--QCLFE--HL-Y--TKDI---FF----RKR
CGNGIVED--QEECDCGPL-R---HC-AK---DPCCMP-NCTLSY-GSTCAFG------L
CCK--NCQYLPSGEVCRKEAN-ICDLPEWCNGTSHKCPDDVFVE

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1094)

NGIPCNT---SAYC--
---YEREC-NDRTA-------------RC--RQIFGR---EA---KSAAE-----ICYTR
VNTQGSRFGHCGLR-------------------GSTYVKCNVSDVLCGRIQCDGVKEVPS
LDQ--HT---TVHWAHY----N-DVNCWGT----------------DY-HHGMK------
-------I---PDIGDVKDGTECGHD---------HLCIH---RQCVHISI-LDS--NCS
PS-FCNM-RGIC-----NN--KHH-CHCNYLWD-PP----------NCEI----------
-QG---HGGSVDSGPPPR---RKRTTRF--------------------------------
---------------------------------------------CFLCLILFI------
-ILCILIL---------C-CIR--------LCLKG-----RK-KEEQEVDQQPTA--VGK
G-LQ----------------------------------------SQPPSMVSQ-RP----
-------QSIPRAPS-----------RISRTPSAIPRT-N------FKSLIQTNF-----
-------Y----------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RPAEA-P---VTLRAPV
L--LLGL-----------WAL--LAPVWCSQGRP------LW-----H-Y---------A
SSEVVIPR

PF01562 // ENSGT00910000144019_0_Domain_1 (249, 428)

KETHHGK-----GV--------QFPGW-LSYSLRFGGQRHVVHMRR-K----
----H-LLWPRHLLMTT--QDDQGALQVD---DPYI------------------------
----PPDCYYLGYLEEVPLS-MVTVDTCYG--GL----R--GIMKLDDLAYEIKPLQ-DS
-RRFEHVVSQIVAE-PN-ATGPTFRDGDNEE--T------DP-LFS---E----ANDSMN
PR--------LSTLLYSSHRGNIKGHVQCSNTYYRIYG--NITTCYTAVVQMFSVIDSIV
QNIDLRYYI------YLLTIYNVRDPAP-VN------QYGV-NSAMFTYFKRTFFD-TFR
-VHSSTLLI----RDAP-----HESNYEP------Q---RYSFCTHL--GLLHIGS----
LGRHY-LLVAVITTQT-LMRSMGV-EY--DD-----------NYCTCQRR--AFCIMQRY
PGI---TDAFSNCSYGHAQNCFVN--S-S--QCVFE--AL-A--PVHN-----ESITMVR
CGNLIVEG--REECDCGSF-K---QC-YA---SRCCRS-DCRLTP-GSICHLG------D
CCT--NCSFSTQGTLCRPIQN-ICDLPEYCPGTTLTCPSNVYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCTE---EGYC--
---YHGNC-TDRNV-------------LC--KAIFGV---SA---EDAPA-----DCY-D
INLESHRFGHCTREQT-----------------ALSYEACVGIDKFCGRLQCTNVTHLPR
LQE--H---VSFHHSIR----R-GFQCFGL----------------DE-HRA--------
--------TGTTDVGRVIDGTPCSRG---------MACNN---TQCNVAITSLNY--DCY
PQ-KCSY-KGVC-----NN--RRN-CHCHIGWD-PP----------RCLR----------
-RG---IGGSVDSGPPPR---RTRSVKQSH------------------------------
---------------------------------------------QAV-LYLRVVF----
-GRIYTFIIA----LL-FGMATNVRTIR------T-----TA-VKEVTATDPE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--LLLIL-------SGLGRLT--SA--------------------GP-----HSET--P
VLQITVPRKIQT

PF01562 // ENSGT00910000144019_0_Domain_1 (253, 429)

NTN---DGDV--S-------ETH-ATYSIKIEGKPYTFLLEK-Q----
------SFLHPHFLVYL--YNESGTLYVD---SSFS------------------------
----KGHCFYQGYVADIPKS-AVTLRTCS---GL---R---GLLQLDNISYGIEPLE-SS
-PTYEHVVYRIKND-AI-G-HFSFQEN----Y-P----VAQY-ID--Q-S------YRIL
VK-------SDINSGAMLSKRTLKIQIIMDKAMYDYMGS-AVAVAVEKVFQIFGLINTMF
SQLNITVML------SSLEIWSDQNKIS-TS-----GHADEILQRFLLWKQKLLF---QR
SHDMTYLLI----YRNH-----ST-YVGA------TY--HGMACDPK-FATGI-AL---Y
PKKITVEAFSVVMAQL-LGINLGL-TYD-DI-----------YNCYCPG---PTCIMNPD
AIRSHGMKFFSSCSMDEFKQIVLQ--PEL--KCFQD--KT-I--SEMT-YQK-S----AT
CGNGIL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EP--TEQCDCGYR-K---AC-TF---KKCCNPADCTLIG-FAECGSG------P
CCNNKTCTIYARGHVCRKSID-MCDFPEYCNGTSEFCVPDVKAADLEYCSN-KT-SYC--
---FKGIC-RDRDR-------------QC--SQLFGK---FS---KSANL-----LCTEE
VNFQNDKFGNCGQ-------------------------RCPFFDILCGKIVCHWIHSELV
PMT--D---LDIQYTYL----G-GHVCLSA----------------HA-RNASK------
--------QL---GTYTEDITACGQQ---------KVCRS--R-GCRYLSE-LNI---TK
CTTNCGQ-NGIC-----ND--RFH-CQCDPGYA-PP----------DCDP----------
-SM-SSPGGSIDDGFWLS---V---DKS--------------------------------
------------------V-PLFP-K---QRAAP-------KNNGLLISFYIFLPL----
--LILI---------A-IVSLKWNKM------KRFW----S---KVGTVSSRS-------
-ISEDSSSN-------NSQSQS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------APSLMGPSWA-QAH-KTGDLWL
P--LLWLF---------------LSLVCCSHARP-----

PF01562 // ENSGT00910000144019_0_Domain_1 (220, 428)

-GW-----R-F---------T
SSEVVIPRKVSHRVS-----GA--------EIQGQ-LSYKIHFRGQRHVVHLKV-K----
----K-SLPPRHFPVIT--DDDQGAMQED---YPYV------------------------
----PRDCYYYSYLEGVPGS-MGTLDTCYG--GL----H--GMLQVDDFTYEIKPLE-SS
-SKFEHV

ENSGT00910000144019_0_Linker_1_5 (428, 501)

ISLLVSE-ER---SEVERCAIEEE-------DKDHAYEE--------ATLAET
PR-------AAPVYLWWPHR

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 740)

KYLKLHYTVTNSLYVLD-T-NQTRIVENVVLINNILDTIF
NQAHYRVHV------RAICIWNDSDRVN---L-YNLATAWLALNRFGLWKWHGWYP-SLP
-HDSSLILT----ARKI-----NYLSHYA------F---QDGICNPN-WGVAYAFV----
GNYHI-FLASSIAAHS-LCHLFGV-NH--DT-----------AGCHCFRR--ASCVMSAE
PGL---LDMMSNCTYGRMHDR-AS--MWD--PCGSI--RN-D--PYTN-FPYV----APR
CGDKIINM--DEECDCGSL-K---AC-SD---DKCCET-HCALST-GSVCSIG------P
CCI--GCRYAQPGKVCRDTPG-ICDLPEYCNGRTHVCPDDLYIQDGTPCSP---LAVC--
---VSGNC-TDRDM-------------QC--QALFGH---QI---KDAAA-----ICYEK
LNLIGDRFGNCGVRVTRG---------------GGKPVTCEGDDVFCGMLHCSAVGQIPG
GGD--HTTFRHILA-------D-NEKCFGY----------------DA-HDG--------
--------TELPEFGLVVDGATCGPG---------RYCLN---QNCTFYQD-INF--DCD
IQ-TCNF-KGVC-----NN--RRQ-CHCMDGWK-PP----------SCAE----------
-RG---PGGSLDSGPPPD---KTLRLQTKI------------------------------
-------------------------------------------IFSLNK-GIFLLL----
-IRFTLFGIA----IL--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
F--LLVLF-------TGLSGLQ--A---------------------GQ-----SPQK--T
ILQTTIP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

EKISSSDM----EED--P-------ENH-IAYLIKIAEKPYFAHLKK-Q----
------SVIAPTAVLYT--YDEHGDRHTQ---PLSF------------------------
----LESCTYSGYIAGFPNS-LVTLNVCS---GL---R---GTIQFPNSSYGIEPVE-AM
-SGFVHVIYEITNE-DP-G-IPVLEEN----E-E----DNWY-KV--S-E------FQFG
SN-------GKKTTFTKLSPQYIEMNVVVDKKLFDYMGS-DDKIVTQKVIQVIGLVNTMF
SKFKLTVII------NSIEIWSKENIIS-LP-----KRPADLLITFLNWKQ---N---HK
-LHISYLFV----FEEQ-----PA-SIGA------LS--PGEVCRED-YDAAV-AL---Y
PRGLSLESYSVIVTQL-LSLGMGL-TYD-NT-----------DTCHCMG---DVCLMTPK
AIYSRGMKDFSTCSLDQFKSLSMS--KNL--GCLRD--WP-M--ERR---TRRRPR--RI
CGNGII

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EG--QEQCDCGTL-Q---NC-TH---RACCDPLLCRLKP-GAVCGSG------G
CCT-QSCKIKPINALCRKKYS-ECDFPEYCNGTHAACVPDTFVRNGEFCKS-GE-AFC--
---YNGQC-RNTDQ-------------QC--MNLLGK---GV---RGAPF-----WCFEE
MNSRGDRFGNCIEH------------------------HCRLENVLCGKLVCTWPYKTLF
LSD--N---ISAVYTHT----R-EDICISL----------------YR-THGIP--KK--
-TMTTYTSLTDRDETFVEDGVICGPE---------MYCMG--T-VCRERRF-LTDFSICN
VSRDCSD-HGTC-----NN--FHH-CHCDKGYV-PP----------NCER----------
-KR-G-QFGSIDDGHQYI---SGRS----L------------------------------
------------M---Q--------Q---SSGFP-------PKQRLQLIFYISLPA----
--VIII---------T-AIIIKQSKL------RQLC----Y---GEGSDSNRS-------
-SSEDSRNN-------TKLTTTGVSSAED-----LP------V---TPDSKRILTVFAMK
------KH----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MW
R--VLFLL-------SGLGGLW--M--------------------------DSNFDS--L
PVQITVPE

PF01562 // ENSGT00910000144019_0_Domain_1 (249, 429)

KIRSIIK----EE---I-------ESQ-VSYQIVIEGKPYTANLMQ-K----
------NFLSHNFRVYS--YNGTGIMKPL---DQDF------------------------
----QNFCHYQGYIEGYPKS-VVMVSTCT---GLR------GLLQFENVSYGIEPLE-SS
-VGFEHVIYQVKHK-KA-D-VSLYNE----KD-I-------E-SRD-L-S------FKLR
SV------------------------------KYNHMGS-GTTVVTQKIFQLIGLTNA-F
VSLNTTIIL------SSLELWIDENKIA-TT-----GDAKELLHTFLRWKRSYLV---LR
PHDVAFLLV----YREK-----SN-YVGA------TF--QGKMCDAN-YAGGV-LL---H
PRTISLESLAVILAQL-LSLSMGI-TYD-DI-----------NQCQCSG---AVCIMNPE
AIHFSGVKIFSNCSIEDFAHFISK--QKS--QCLHN--QP-R--LDPF-FK----QQ-AV
CGNAKL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 879)

EA--GEECDCGTK-Q---NC-FLIG-AKCCDTATCRFKA-GSDCAEG------P
CCE--NCLFMSQERICRPSFE-ECDLPEYCNGTSASCPENHFIQTGHPCGP-NQ-WVC--
---IDGVC-MSGDK-------------QC--MDTFGG---EA---EFGPR-----ECYSY
LNSKTDVSGNCGIGDS------------------G-YIQCEADNLQCGKLICKYAGEFLL
QIP--R---ATIIYANI----S-GHLCVAV----------------EF-ASDH-------
---------EDSQKMWIKDGTSCGPN---------KVCKN--Q-RCVSSSY-LGY--DCT
TD-KCNH-RGVC-----NN--KKH-CHCSASYL-PP----------DCSV----------
-QSDTWPGGSIDSGNFPL---VAV--P---------------------------------
------------------ASLPER-R----YMENV-YH----SKPMGWPFFLFIPF----
--FIIF---------C-VLIAIMVKVYFQ---RKKW----R---TEDYSSDEQ-------
-PESESEPK-------G-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------PALP--SSPLDQWFQNCVSTMTVSEA-L---VHLRITL
L--LHCL-----------GMFL--------S-FS------

PF01562 // ENSGT00910000144019_0_Domain_1 (221, 429)

GH-----A-Q-AEHS-QYQS
PPEVVIPLKVTGRGR-----GT--------KSPGW-ISYSLHFGGQRHIVHMKV-K----
----K-ILLARHLPVFT--YTDQGALLED---QPFV------------------------
----KNDCYYHGYVEGDPES-LVALSTCFG--GF----R--GMLQINDIAYEIEPLM-FS
-ATFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKMDSE-ET--QFPTTRFGFMQEE-I-----VHK-LEF-Q-EI-----GNST
LK-------QSSHMGWWTHVW

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 754)

FLELAVVVDHTLYLRFEQ-NVSTVQEEIYNVVNIVDSIY
DILGVNVLL------FGVEVWTDSNFIV-V------DNVKNVVVEFCKWKVKNFSH-RVQ
-HDVIQLYI----NKGL-----KG-LPGI------AY--MGGVCKTP-YNCAVITS----
FKQNV-NHFANFVAHE-LGHVLGM-PH--DD-----------TTCSC--GH-RICIMNAK
KVL---SARFSNCSYAHLWR---T-LTQG--DCLRY--TP-Q--AGEI---FT----LKR
CGNGVVEE--EEECDCGPL-K---KC-AQ---DPCCLP-NCVLTS-ESACSFG------L
CCK--NCKFLPSGEVCRERVN-ECDLPEWCNGTSHKCPDDVYVQDGNPCRD---NAYC--
---YEKRC-NDRSE-------------QC--KHIFGK---EA---KSADK-----DCYEK
INTQGDRFGHCGMN-------------------GSHYIKCNISDVLCGRVQCKNVALIPF
LKE--HS---TVLWTRF----N-DITCWGT----------------DY-HFGMT------
-------I---PDIGEVKDGTECGQK---------QICMH---RKCVSMSL-LKS--DCS
S-QTCNM-RGVC-----NN--KHH-CHCNSQWS-PP----------NCLA----------
-IG---DGGSVDSGPPPK---K--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
S--LRFLF-------SGLQTVS--E-------------------------------PVQA
DFQITIPEKIGSTID----ED---F-------QSQ-VFYKILIEGKTYTV

PF01562 // ENSGT00910000144019_0_Domain_1 (291, 491)

NLTQ-X----
------XXXXXXXXXXX--XXXXXXXXXX---XXX-------------------------
---XXKFCYYQGFIEGFPNS-MAIISTCT---GLR------GLLQFDNVSYGIEPLE-SS
-IGFEHVIYQVKHK-NK-G-VSLYAE----KD-I-------E-SRA-L-P------YKIQ
SI-------EXX----XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXX----------XXXXXXXXXX-XX-----XXXXXXXXXXXXXXXXXXX---XX
XXXXXXXXXXXXXYREN-----IN-YIGA------TY--QGKMCDRN-YGGSV-LM---H
PKTISLESLAVVMVQL-LSLSMGV-PYD-DR-----------SKCQCPG---AVCIMSPE
AIHSSGVKSFSNCSMEDFARFFSK--PTS--QCLQN--HP-R--FDPS-YK-----A-AT
CGNGELEE--GEQCDCGSK-E---RV-LRGG--ICCNPQRCTLTD-TSACGQG------D
CCN--NCQFRAKGEVCRAPSD-DCDLTEYCNGTSAECQEDLYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

NGHPCEK--K-WIC--
---LNGRC-MNGSK-------------QC--ITTFGD---DT---SFASD-----NCFKE
INSRKDQSGNCGSSGG------------------Q-YTPCAAGDLKCGKLICSYAKRML-
-IQ--N---ATVLYTNV----K-GEICVTV----------------DY-YSNN-------
---------TESNMMWVSEGTVCAKN---------KXXXXXXX-XXXXXXX-XXX--XXX
XX-XXXX-XXXX-----XX--XXX-------XX-XX----------XXXX----------
-XXXXXXXXXXXXXXXXX---XXXXXX---------------------------------
----------------XXXXXXX--X---XXXXXX-XX----XXXXXXXXXXXXXX----
--XXXX---------X-XXXXXXXXXXXX---XXXX----X---XXXXXXXXQ-------
-LESEGETK-------E-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MSVA---ASVKGITSILSSLQITKVA
LKEA------------------------KITSHIWAAQQLNL-GLRLVPG----HPSVKI
G--IL-------------VLLIFLPSTFCDIG-----------------------PVYYS
SYETVIPKRLPVEGS------E--------D

PF01562 // ENSGT00910000144019_0_Domain_1 (272, 429)

PGGR-VSYMLLIQGQQQLLHLKV-K----
----G-DYSVNNFPVYS--YHN-GILEQE---MPLL------------------------
----SQDCHYEGYMEGVPGS-FVSVNICS---GL----R--GILIKEDTSYSIEPIL-SS
-KGFEHILYTVGLQ-------PQASCSVTPK-GS-SGDTSQQ-QR----------NGKPD
DP-------WEL-SDLRSHTKYVEMFVVVNHQRFQMWGS-SVNETVGAVVDIIALTNSFT
RGLNTEVVL------VGMEIWTEGDPIE-AP-----VDLQATLRDFNRWRQEKLVG-RLR
-HDVAHLIV----GHHP-----GE-NEGQ------AF--LHGACSGG-FAAAVEAF----
PHEDV-LLFAALMAHE-LGHNLGI-QH--DH-----------QACICDH--KHFCLMHEN
ITK---GSGFSNCSSDDFYRFLHD--HRG--ACLLD--RPWH--QSRK-RR------ATR
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 879)

ED--WEQCDCGP------AC-DH---HPCCDP-TCRLKL-GAECSDG------L
CCY--KCHVKKKGVLCRPVED-VCDLPEYCNGLSQECPANSYKQDGTLCDR---IYYC--
---SGGWC-KNPDK-------------QC--TKIYGY---PA---RSAPD-----DCYIL
MNTKGNRFGNCGHPTT-A---------------NARYETCSDDDVFCGKLICTDVRYLPQ
VRP--QH---TLLQVPY----G-DDWCWSM----------------DAYNI---------
--------TDVPDFGDVQSGTYCAPN---------KVCME---YYCTDHTV-LQY--NCK
PEELCHG-KGVC-----NN--LRH-CHCDDGFA-PP----------DCNG----------
-PG---DGGSVDSGPVGK---PADRNLSLFVLFG--------------DK----------
-------------------------T---QSKADD--EE----VNMK-VVVLVVPI----
-FLVLLLCA-----LM-LIAYLWSEVQE-----------AVS---PGSSSSSST------
ETSEGGSS-------I--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RPAQT-L---LSQGRLL
L--VLVLT-VLL--LDSLGDDV-------IF-LP------EW-----E-F---------D
SYEITIPEKLSFRGE-----AQ--------GV

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

VSP-VSYLLQLKGKKRVLHLWP-K----
----R-FLLPQHLRVFS--FTERGELLED---RPYI------------------------
----PKDCNYMGSVEGSLDS-KATISTCMG--GL----R--GIFSIDAEHYQIEPLK-TS
-PTFEHVV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YRLK-K-E---QSGSQACGLSDEE-L-----EWQ-MAP-Y-EKQ--A-----
-R-------LRDFPGSYKHP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYLELVLVFDQSRYRFVNS-NLSQVIHDAMLLTGIMDTYF
QDVRMRIHL------KALEVWTDFNKIR-VG----YPELAEVLGRFLLYKKNVLNA-RLS
-SDWAHLYL----QRKF-----ND-ALAW------SF---GKVCSLD-LAGSASTL----
PGTNV-LAPATWSAHE-LGHAVGM-LH--DE-----------QYCQCRGR--LNCIMGSG
------RAGFSNCSYIAFFKHVS--SG-A--TCLNN--IP-G--LRY---V------AKR
CGNKIVED--NEECDCGSP-E---EC-YK---DGCCKS-NCKLQP-GANCSVG------L
CCQ--DCQFRPSGYVCRQEEN-ECDLAEYCDGNSSHCPNDVYKQDGTPCKY--E-GRC--
---FRKGC-RSRYM-------------QC--QSIFGS---DA---REAPS-----QCYDA
VNLIGDQFGNCEIT-G-----------------IRHFKKCGSENSICGRLQCINVETIPD
LPE--HT---TVISTHL--RAE-NLLCWGT----------------GY-HLSMK------
-------PMAIPDVGVINDGTSCGED---------RVCFK---KNCVNSSV-LKF--DCL
P-EKCNT-RGVC-----NN--RKN-CHCMYGWA-PP----------FCEE----------
-VG---YGGSIDSGPPGR---LTG------------------------------------
--------------------------------------V----IPLSIR-IVSIIM----
-FRLILLILS----V--VFV--FFRQEIG-NYLNPS---KEE-KMPPSEAKPGQEESKAK
TGQEESKAKAGKEE-SKAKAGREESKAKAGQEE----SKANVE-SKPPKAKNVKKPKK--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MGAVED-G---ASLRVAL
L--WFWL-----------EVSL--------S-SS------SF-----S-Q-AVPT-QCFG
SP

PF01562 // ENSGT00910000144019_0_Domain_1 (243, 429)

EVVIPLKVDSRSR-----GV--------KTPGW-LSYSLLFGGQRHVVRMRV-K----
----K-LLVSTHLPVRT--YTEQHALLED---HPFI------------------------
----PDDCYYHGYVEGALES-LVVFSACFG--GL----R--GMLQINDLMYEIEPIR-HS
-TAFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKLNNN-DT--XFLPMKCGLTEEK-T------HQHLEF-E-VG-----ENLA
PK-------YNSAHDWRTHTW

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 860)

FLELVIVIDHDFFTYSQG-NLSKVQEDVFLVVSIVDSMF
RQLSTYVTL------IGIEIWNQGNIFQ-MI------SIGQVLGDFSEWKKISFS--QLQ
-HD---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------AVN-ECDLPEWCNGTSHQCPQDAYVQDGIPCSE---SAYC--
---YQKQC-NNHDQ-------------QC--REIFGQ---SA---KSASQ-----NCYRE
INSQGNSFGHCGIN-------------------GTVYLKCNMPDIFCGRVQCESVKNMPH
LQD--HS---VLKSTPV----I-GFTCWSV----------------GH-HLRAS------
-------I---PDIGEVKDGTTCGAG---------KICIR---KKCVSLSV-LSQ--DCL
PE-TCNM-KGTC-----NN--KHH-CHCAYGWS-PP----------DCLH----------
-RG---YGGSIDSGPAST---TERVSWK--------------------------------
-------------------------------------------------Q--VVIP----
-FLSVLIC---------LSTVGLY------IY----HRIHSG-PKKTE--AHASG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MVAMSEA-L---VHARITL
L--QAWL-----------RMLL--------F-SS------VW-----P-L-TWCA-EYKG
PPETVKPLRVTVSSK-----DM--------GLA

PF01562 // ENSGT00910000144019_0_Domain_1 (274, 429)

GW-MSYSLHFGGQRHIISMKS-K----
----N-FLESRQLPVFT--YNDQGVLFED---RPFV------------------------
----QNDCYYLGFVDGDLES-MAALTTCFG--GF----Q--GIFQINDTAYEIKPKS-PS
-STFEHLL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKIDSE-KT--QLRPMRCGLTDEE-I-----AGQ-VRL-Q-EN-----GKSA
RM-------QSVYGSWWSHGL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 755)

YIKLALVIDHEQYLYRKR-NTSLVIRDVLNIMHGINHLL
LSVDINVVL------LGLTIWTNGNPIP-V------QDIYALLPAFCTWKGTNLNS-QIP
-YDIAHLFV----NYTF-----SN-YFGI------AY--VGTVCNKT-FGCGIDSI----
VEDDF-LTIGHIVAHE-IGHNLGM-PH--DG-----------RLCTC--GE-EPCLMSAT
MDS---SGKLSNCSYEVLWA----HMIKK--SCIHR--EP-R--PSDI---FQ----VKV
CGNGIVEE--GEQCDCGTS-E---NC-RR---NRCCMP-SCILRS-RAKCDTG------L
CCN-HKCQIQPSGTLCRAQEN-ECDLPEWCNGTSHECPEDLFVQDGTSCPG---DGYC--
---YEKRC-NSHNE-------------HC--QRLFGQ---LA---MKASD-----SCYKE
LNTRGDRFGNCGFI-------------------DNEYVRCEISDILCGRIQCDQVGTLPT
LQN--HY---TVHWTHF----N-SVSCWST----------------DY-HLGMK------
-------I---ADLGDIKDGTNCGPQ---------HVCIA---RKCVNKPS-WVS--DCT
RE-TCNM-KGVC-----NN--KQH-CHCDVGWS-PP----------NCQE----------
-TG---TGGSIDSGTPGN---EVDE--DEGV-----------------------------
---------------------------------NK--KD---VSKKSNVIVWLLPI----
-ICV---A---------VVLFV-------LFCLSGA-TKKSP-TQPVTAAVT------QP
P-----------------------------------------EETVKPPDEVVEPP----
-------E--ETV-----------------------KP-PDEGD--YP------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------MHK--EK-K--SIGI---LP----DKL
CGDGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

DD--GEQCDCGSA-K---SC-AD---DPCCKP-SCTLKD-GAACAFG------L
CCE--YCQIMPAGTLCRKKDN-ECDLPEWCNGHSHKCPNDVYLLDGNPCRD---GGYC--
---YEKRC-NNRDK-------------QC--KQIFGK---EA---RSADH-----SCYRE
LNTHGDRFGNCGMI-------------------RGAYLRCHDPDILCGRVQCENVTRIPF
LRD--HS---TVHWTHL----N-GVTCWGT----------------DY-HLGMX------
-------I---PDIGIVKDGTDCGPE---------HVCIN---KKCVSKPI-WTS--QCS
PK-TCNM-KGVC-----NN--LHH-CHCNQGWD-PP----------HCLK----------
-SG---IGGSVDSGPPNY---N----AKKH------------------------------
---------------------------------KK--SI------GLVSLFLIL-F----
-ACFSVLF---------I--VF--------LFILR----SYN------------------
--IELP-M-----SEKPQVSSSE----------------K--------KEDGNDVM----
----------NTEKE---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------XR

PF01562 // ENSGT00910000144019_0_Domain_1 (372, 428)

GALEGAPGS-LATFSTCYR--KM----W--GMLRLHGRLYQVEPLP-AS
-ATFEHRVSWQD-E-K---APGNLTCGLTGEE-I-----ARQ-AAQ-F-RPP--ASF---
-R-------QFDWHDSYIHPKYVELAVAVDNARYRFRKN-NISAVIQDAIFLVNFADSHF
QELKAHISL------KAVEVWTDRDKVS-TK----HSRIYRLVNDFSRYQLNNLYP-RIQ
-HDFSHLFV----SKSF-----GN-LTGW------AN--FGGACNAS-RMASVSSL----
TGQSL-LDPALWFTHE-LGHGCGM-NH--DD-----------RYCKCKG---TSCIMETA
G-V--RNGGFSNCSFSYFFSFTNQ--L-A--PCLSN--VP-E--QLL---V------VDT
CGNKVVEW--GEECDCGSE-E---EC-EK---DACCLS-NCTLSP-GAACASE------L
CCK--GCQFVPATTVCRPRQT-ECDLDEFCNGTSSMCPEDVYKQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1091)

DGTPCSE--G-AIC--
---YRGGC-RSHLR-------------QC--RALFGK---EA---VDAPL-----LCYEE
VNGYVDRFGNCGLE-Q-----------------HL-YRECAVHDMLCGRVQCVNVKTIPS
MPD--HT---SIIQTHV--KDS-NTMCWGT----------------DY-HAAMQ------
-------TLRIADVGDVEDGTFCGTG---------LICMN---RTCLDASL-LNY--DCE
P-QKCNH-RGVC-----NN--KKN-CHCKYGWA-PP----------LCET----------
-PG---DGGSIDSGPPGK---PV-------------------------------------
--------------------------------------------VATFQ-VWPIFI----
-LRIILFVAS----F--ILA--SVKCITL-CKKLPF---SKI-KTASFKDTA-R-G----
-LFAESKTATS-KEDFEWKSG---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MECFIMLGADA-R---TLMRVTL
L--LLWL-----------KALP--------S-LI------DL-----S-Q-TGST-QYLS
SPE

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

VVIPLKVTSRAR-----GA--------KNSEW-LSYSLVFGGRRHVVHMRV-K----
----K-LLVSTHIPVLT--YTEEHTPLSD---YPFV------------------------
----PSDCYYHGYVEGALES-LVAVSACNG--GL----Q--GVLQMNDFSYEIEPIK-HS
-STFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YTLNNN-KT--QFPPMLCSLREKR-L-----LYQPFGV-E-EA-----KKSA
MK-------QNYG-KLWPHMW

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

FLELAVVVDYGFFTNAQQ-NLSKVRGDVVLVVNMVDSMY
KPLDTYVTL------VGIEIWNRGNVLP-ME------NIHQVLEDFSHWKQISLS--QVH
-HDAAHIFI----RSSL-----IS-VLGI------AY--IAGICRPP-LDCGVENF----
QGDAW-SLFANTVAHE-LGHTFGM-KH--DE-----------ESCSC--GK-SGCVMSTF
RVP---AERFTNCSYSDFMK---TTLNQG--TCLYN--HP-R--PGAG---FL----VKR
CGNGMVES--EEECDCGSV-Q---EC-EQ---DPCCFL-NCTLRP-AAACGFG------L
CCK--DCKFMLLGELCRPKIN-ECDLPEWCNGTSHQCPEDGYVQDGVSCGA---GAYC--
---YQKQC-NNHDQ-------------QC--REIFGK---GA---RSASH-----NCYKE
INLQGNRFGHCGTN-------------------GTVFLKCRMSDVFCGKVHCENVEDIHH
PQA--PY---VLQNIYA----N-GITCWST----------------GH-CLGMG------
-------V---PDVGEVKDGTTCGVG---------KICIH---KKCVSLSV-LSN--ACL
PE-TCNR-KGVC-----NN--KHH-CHCDYGWS-PP----------FCLH----------
-RG---YGGSIDSGPTSQ---KRRVIIT--------------------------------
-------------------------------------------------VLSITVP----
-ALSILIC---------LFMAGLY------RLYCK---IPSG-PKETK--ASSPG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSAEV-R---VTLRAPV
L--LLGL-----------WAL--LAPVWCSQGRP------LW-----H-Y---------A
SSEVVIP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 428)

RKETHHGK-----GV--------QFPGW-LSYSLRFGGQRHVVHMRR-K----
----H-LLWPRHLLMTT--QDDQGALQVD---DPYI------------------------
----PPDCYYLGYLEEVPLS-MVTVDTCYG--GL----R--GIMKLDDLAYEIKPLQ-DS
-RRFEHVVSQIVAE-PN-ATGPTFRDGDNEE--T------DP-LFS---E----ANDSMN
PR--------LSPSLYSSHRGNIKGHVQCSNSYYRMYG--NITTCYTEVVQMFSVIDSIV
QNTDLRYYI------YLLTIYNNHDPAP-VN------QYRV-RSAMFTYFKRTFFD-TFH
-VHSSTLLI----KEAP-----HESNYEP------R---RYSFCSHL--SLIHIGT----
LDRHY-W-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MSVA---ASVRDSASILPSLWKRQVA
MSEA------------------------IRALQTWAPHTKGL-RLAPV-PGL-SCARLGI
L--LF-------------LVLISLPSLYG

PF01562 // ENSGT00910000144019_0_Domain_1 (210, 429)

DLG-----------------------SLHHS
SYEIVIPKSLTVEGR------E--------DQVEK-LSYVLFMQGQRQLIHLTV-K----
----R-DYFVDNFPVFS--YHN-GILGQE---MPPV------------------------
----SQDCHYEGYIEGVPGS-FVSVNTCS---GL----R--GLLIKEEKSYGVEPVH-SS
-KRFEHVL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YAMAHE-------ARVSCGVTSK-DSQVASTSRR-PE----------SGKPH
SW-------QVP-SDLWSHI

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYVEMVVVVNNQRFQMWGS-DVKQTVQRVMDIIALANSFT
RGINIEVVL------AGMEIWTEGDLTE-VP-----VDLQVALRNFNSWRQENLFH-RVK
-HDVAHMIV----GQHP-----KE-DTGQ------AF--LSGACSSD-FAAAVESF----
HHEDV-LLFAALMVHE-LGHNLGI-RH--DH-----------SACICKD--RPFCLMHEN
ITK---GSGFSNCSSDFFHQFLWE--HKG--ACLFN--KP-G--HKGRLRR------ASR
CGDGIVEG--PEQCDCGS------KC-EM---HPCCDT-RCMLRE-HAECSDG------L
CCD--KCRLRFKGFMCRAALG-ECDLPEYCNGFSGECPRDSYKLDGTVCDR---IHYC--
---AGGRC-KNPDN-------------QC--MDIYGS---PA---RSAPE-----NCYVS
MNTRGDRFGNCGTSSS-P---------------RLTYLKCAGDNIFCGKLICTNVREVPQ
IKP--NH---TLIQVAH----N-DGWCWSM----------------DAYDT---------
--------ADIPDDGDAHTGTLCAPH---------KVCMN---HLCTDHTS-LGY--SCE
TTELCNG-KGVC-----NN--FRH-CHCEEGYA-PP----------DCKD----------
-PG---DGGSVDSGPPST---SIQLSSEGQS------------------E----------
-------------------------T---SKTRSS--QT----EYLG-NIVFILPS----
-LLLIFL-V-----IV-LLVSIKTGVET-------------I-ESPPHTSEVDS------
EESSSEVFI------M----------------------------ELLPVGIIEEAE----
--------------------------E--GPPPEQGPP----------------------
------------------------------PEV-----------PPTGAPPPEAPPPA--
------------------GPPPEA---PP--------------PAAPPPEAPPPGQPA--
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RPAEV-R---VTLRAPV
L--LLGL-----------WAL--LAPVWCSQGRP------LW-----H-Y---------A
SSEVVIPR

PF01562 // ENSGT00910000144019_0_Domain_1 (249, 428)

KETHHGK-----GV--------QFPGW-LSYSLRFGGQRHVVHMRR-K----
----H-LLWPRHLLMTT--QDDQGALQVD---DPYI------------------------
----PPDCYYLGYLEEVPLS-MVTVDTCYG--GL----R--GIMKLDDLAYEIKPLQ-DS
-RRFEHVVSQIVAE-PN-ATGPTFRDGDNEE--T------DP-LFS---E----ANDSMN
PR--------LSTLLYSSHRGNIKGHVQCSNTYYRIYG--NITTCSKEVVQMFSVIDSIV
QNIDLRYYI------YILTIYNSRDPAP-VN------DYRY-RSPILNYFRRTFFD-TFR
-VHSSTLLI----KEAP-----HESNYEP------Q---RYSFCTHL--GLLHIGT----
LGRHY-LLIAVITTQT-LMRSMGV-EY--DD-----------NYCTCQRR--AFCIMQRY
PGI---TDAFSNCSYGHAQNCFVN--S-S--QCVFE--AL-A--PVHN-----ESITMVR
CGNLIVEG--REECDCGSF-K---QC-YA---SRCCRS-DCRLTP-GSICHLG------D
CCT--NCSFSAQGTLCRPIQN-ICDLPEYCPGTTLTCPSNVYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCTE---EGYC--
---YRGNC-TDRNV-------------LC--KAIFGV---SA---EDAPA-----DCY-D
INLESHRFGHCTREQT-----------------ALSYDACVGIDKFCGRLQCTNVTHLPR
LQE--H---VSFHHSVR----G-RFQCFGL----------------DE-HRA--------
--------TGTTDVGRVIDGTPCSRG---------MACNN---TQCNVAITSLNY--DCY
PQ-KCSY-KGVC-----NN--RRN-CHCHIGWD-PP----------RCLR----------
-RG---IGGSVDSGPPPR---RIRSVKQSH------------------------------
---------------------------------------------QAV-LYLRVVF----
-GRIYTFIIA----LL-FGMATNVRTVR------T-----TA-VKEVTATDPE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MEASEA-S---VSMRI

PF01562 // ENSGT00910000144019_0_Domain_1 (179, 429)

VI
L--LLWV-----------GVFL--------S-LS------GL-----S-Q-ARLS-QHLS
SPEVVVPLKVTSKSR-----GS--------QVPSW-LSYSIQLGGWRHIIHMRV-K----
----K-FLVSRHLPVFT--YTDQHVLQED---QPFV------------------------
----PDDCYYHGYVQGVPGS-LVALSTCSG--GF----Q--GMLQINDLAYEIEPIR-HS
-TTFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YKIDSD-GT--QFPPMRCGLTEEK-I-----ARQ-LEL-Q-EL-----PKST
LM-------QSSYMNWWTHL

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

RFLELAIVVDHFRYIYSGS-NVSAVQRELLNVVSMINLLY
RPFKLNVIL------TGVEVWNQRNLVP-TD------DIDQLLDDFGLWKFVNLDG-RLQ
-HDVVHLFI----KKFF-----GV-KLGI------AY--TSGVCRKP-FNTGVDVF----
LDHNV-NSFALTVIHE-LGHNMGM-QH--DT-----------AWCVC--GF-KWCVMAAM
KRL---TVKFSNCSYAQYWD---TTIRTG--SCIYT--PP-S--PGNI---FS----LKR
CGNDVVEE--GEECDCGSV-K---QC-EQ---DPCCLL-NCTLSP-GSACAFG------L
CCK--DCKLMPSGTLCRQQIS-ECDLPEWCNGISHQCPEDGYVQDGIPCGD---NAYC--
---YEKSC-NSHDK-------------QC--REIFGE---DA---KSASQ-----ECYKE
INSQGNLFGHCGLN-------------------STTYLKCNTSDIFCGRVQCENVRNIPH
LRD--HS---ALQHTHI----N-GVTCWSV----------------GY-YLGIN------
-------T---PDIGEVKDGTMCGSR---------KTCIQ---KKCVSLPL-LSQ--VCL
PE-TCNM-KGIC-----NN--KHH-CHCGYGWS-PP----------YCLH----------
-RG---YGGSVDSGPASA---RKGVFFL--------------------------------
-------------------------------------------------V---MIL----
-SLSVLLL----------LLTTVF------IYLQKCVG----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MY
Y--IINII-------F----------------------------------------D--I
LLQIL-NHSLR--HFKHYLE

PF01562 // ENSGT00910000144019_0_Domain_1 (261, 429)

EL--A-------DEQ-VSYIIPIDEKPYTVHLKQ-R----
------FFLANDFMVYL--YNQ-GSVNSH---SSNI------------------------
----QTQCYYQGYIEGYLNS-LVTLTTCS---GL----R--GILQFENVSYGIEPLE-TA
-VEFQHLL

ENSGT00910000144019_0_Linker_1_5 (429, 488)

YKLGHE-NN-E-FAGLTKD----N-R----DTEE-T-P-V-D------SSIF
IS-----

PF01421 // ENSGT00910000144019_0_Domain_5 (488, 760)

EKV---------------------SCYDYLGS-DSMIITNKIIEIIGLINSMF
AQFKITIVL------SSLELWSDKNKIS-TV-----GEADELLNRFLEWKKSYLT---LR
PHDIAYLFI----YRDY-----PE-YMGA------AF--PGKMCVTS-YSAGI-AL---Y
PREITLEAFSIIVTQM-LGLSLGI-SYD-DP-----------KKCQCSG---AICIMNPK
ALQSSGVKTFSSCSLSDFENFISN--VGA--QCLQN--KP-Q--MQM----PP--A--SI
CGNGRVEI--NEICDCGTE-E---QC-GP---DSCCNPRTCMLKP-NAQCDRG------S
CCN--NCRFLQAGTTCRPTAHPECDISETCNGSSGSCPPDVTIHDGHSCKN-NK-AFC--
---FEGDC-RDLDA-------------HC--ERIFGK---GS---KNAPF-----ACYEE
IQSQNDRFGNCGKER-------------------GRFKYCAWRDLICGRLICTYPSQTPF
LQE--N---ASVIYAFV----R-NVVCITI----------------HY-TLAK-------
---------GLEDPMIVKNGSVCDDE---------RICVN--R-ECVESRT-YTARSHTC
S-LKCSG-HGVS-----NR--VVH-VS--PNLI-LD----------IFQQ----------
-LS---LIYLIF--IGFL---LC-------------------------------------
--------------------LIME-R--VFA-K--------ARNKLLLCVYIGLPV----
--LAIA---------VIIA-VSWKPL------KKRF----T--KKEESQTSHS-------
-TTSPSSMR-------FFLKYLNSIYER--------------------------VCQNYF
F---------LPFELTY------------------------------FYRLLK-------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------GQG-
L--LLRLG--I---SVVLLGPLMPS

PF01562 // ENSGT00910000144019_0_Domain_1 (206, 429)

TDGCSP-PT-------P-----G-F---------A
SYEVIVPRKLAPKEA-----SA--------P-KDK-VSYAIKAEGKIHIVHLKQ-K----
----K-GFLVKNFPVFT--YDDRGQLKVD---QPHI------------------------
----PDDCYYHGYVEDTPES-LAALNICS---GL----R--GFFQIGSLSYGIEPVE-NS
-FTFQHLLYRSEEM-----EPMPVTCDVTDGE-S-----KRP-AAL-M-ESR--KDLT--
---------GKDLTIRFRHTKYIELFIVGDKNLFDHHGK-NQTNVTYFVVDTVNMVDSHF
QPLKIRVLL------IGLEIWTQSNLIR-IP-----QDIRLLLQGFNDWRRLNLAQ-RVK
-HDVAHLFI----YKNF-----GK-LVGR------AY--VSGICENY-YGAAVEAY----
IYKGP-ILFSKVVCHE-LGHNLGM-EH--DQ-----------EGCMCGNQ--KSCIMSEG
N-S--KTSLFSNCSKEDFLYLMDQ--GKG--NCLYN--VP-G--PHKL-FT------IQR
CGNKVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

DQ--GEECDCGDR-I---QC-RK---DPCCHH-NCTLKR-GAVCSVG------Q
CCR--KCKFLPSGKTCRAISD-ECDLPEYCNGIFEWCPEDVYEQDGNPCSD--N-GYC--
---YKGKC-ATHNL-------------QC--ESIFGK---GA---KAAPK-----MCFNE
LNLKADRFGNCGG--DGK---------------ETEFAKCDLNNSLCGRLQCVNVKTIPV
LEE--YE---TIIQTPV----V-NGWCWGI----------------D---AG--------
--------IDIIDIGMVIDGTMCGKT---------KLCLN---RTCTAASM-IKK--ACN
ENIHCSG-KGVC-----NN--NKN-CHCIWGWA-PP----------NCQF----------
-HG---FGGSIDSGPPPS---KLH------------------------------------
----------------------------------Y--EI----WWVY----WAIFGLG-L
LLLIGLIA------AA-I------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MVAMSEA-L---VHARITL
L--QAWL-----------RMLL--------F-SS------VW-----P-P-TWCA-EYKG
PPETVKPLRVTVSSK-----DM--------SL

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

AGW-MSYSLYFGGQRHIISMKS-K----
----N-FLESRQLPVFT--YNDQGVLFED---RPFV------------------------
----QNDCYYLGFVDGDLES-MAALTTCFG--GF----Q--GILQINDTAYEIKPKS-PS
-STFEHLL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKIDSE-KT--QLRPMRCGLTDEE-I-----AGQ-VRL-Q-EN-----GKST
RM-------QSIYGSWWSHGL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 755)

YIKLALVIDHEQYLYRKR-NTSLVIRDVLSIMQGINLFL
LSVDINVVL------LGLTIWTNGNPIP-V------QDIYALLPAFCTWKGTNLNS-QIP
-YDIAHLFV----NYTF-----SN-YFGI------AY--VGTVCNKT-FGCGIDSI----
AEDDF-LTIGHIVAHE-IGHNLGM-SH--DG-----------ILCTC--GE-ESCLMSAT
MDS---SQKLSNCSYEVLWA----HMIKK--SCIHR--EP-R--PSDI---SQ----LKV
CGNGIVEE--GEQCDCGSS-E---DC-KR---NRCCMP-SCTLRS-KAKCDTG------L
CCN-RKCQIQPSGTLCRAREN-ECDLPEWCNGTSHECPEDLFVQDGTSCPG---DGYC--
---YEKRC-NSHND-------------HC--QRVFGQ---LA---MKASD-----SCYKE
LNTRGDRFGNCGFI-------------------DNEYVRCEISDILCGRIQCDKVGTLPI
LQN--HY---TIHWTHF----N-SVSCWST----------------DY-HLGMK------
-------I---ADLGDIKDGTNCGPQ---------HVCIA---RKCVNKPS-WVS--DCT
PE-TCNM-KGVC-----NN--KQH-CHCDVGWS-PP----------NCQE----------
-TG---TGGSIDSGSPGK---EVDEDEDKGV-----------------------------
---------------------------------SK--KD---ASEKPNVIIWLLPI----
-ICV---A---------VVLSV-------LFCLSGA-TKKSR-E----AAAS------QP
A-----------------------------------------GERVKPPYEGAEPP----
-------Y--ETV-----------------------KP-PDEWD--NP------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

PF01562 // ENSGT00910000144019_0_Domain_1 (279, 429)

YILTVEGKPYTIHLEK-H----
------LFIPEDFRIYM--SDETGSSMSD---STHI------------------------
----KGDCYYRGSIEGIPGS-AVTLSTCA---GLR------GLLQFHNTSYGIEPLG-SS
-PIFEHFVYRLRNE-NT-V-GFLFAQS-HPG--A-AGRGLQE------------------
-----------PPSDAAQLPKYIEVYAVLDKALYNYLGS-DQNVVTQKMIQVFNFVNSIF
NPLNVTVVL------SSLELWMQENRIP-TD-----GAADELLQRFLQWKQSHLA---LR
PHDVSCLFV----YRDQ-----AD-FTVA------TS--PGTLCRSD-ASGAV-AV---L
QRAVTLESFSVLLAQL-LGRSMGM-GFD-DG-----------RGCHCPT---YSCVMESA
AIHISGTKAFSSCSTADLEQFLRR--DAG--RCLLH--SP-Q--LRGS-SP----RRAPI
CGNGVVEQ--GEQCDCGST-E---AC-SK---DKCC-TKGCVFKP-GVKCSSG------L
CCE--QCQFKAANTLCRPAADAQCDLPEFCNGSSASCPPDVYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGHSCEH-NT-GYC--
---YHGQC-QSAEL-------------QC--QRLYGR---GS---RSAPV-----VCYEE
LNSQRDRFGHCGYHPR------------------HGYKACAWRNLRCGKLICTYPHSTPL
EID--S---AAVVYAQV----R-EMGTAVSTTPATATMGSASLLSCSA-SSSM-------
---------GEADPFL

ENSGT00910000144019_0_Linker_9_10 (1097, 1139)

VKDGTKCGPG---------KVCMN--G-TCHPHSI-LNY--D

PF07974 // ENSGT00910000144019_0_Domain_10 (1139, 1188)

CN
VEKKCHG-HGVC-----NN--KKN-CHCHPGWN-PP----------HCRI----------
-QG-SALGGSIDSGQRLR---EMES-----------------------------------
---------------------HSP-K---VSPKDM------LKNALLLSFCLLIPI----
--LICI---------V-ILVMKWNRL-M----RRCA----R---RE-MEAADS-------
-TGGEISSI-------GSNESSGSSQSS------RA------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------GILQFENVSYGIEPLE-YA
-VEFQHLLYKLGKE-NS-E-FSIFNNR----K-K----NTEK-Y-P-M-D------YNIF
IS-----KQLESD-VTDLFPLYLEVHIVMDKALYDYLGS-DSMIVTNKVIEIVGLVNSMF
TQFKVTVVL------SSLELWSDKNKIS-TA-----GEADELLHRFLEWKLSYLT---LR
PHDIAYLFI----YRDY-----PY-YVGA------TF--PGKMCVTR-YSAGI-VL---Y
PKEITLEAFSVIVTQL-LALSMGI-SYD-DP-----------KKCQCSE---STCIMNPD
AMQFSGMKTFSSCSFSDFKHFVSN--VGA--RCLQN--KP-Q--MQI----RA--R--AV
CGNAVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EG--NEVCDCGNA-D---QC-GP---NNCCDPATCNLKD-GAQCHRG------A
CCR--DCQIQAAGFECRPSRHPDCDLSEFCNGTSSECAPDVTIQNGNRCKN-RR-FLC--
---YAGAC-ADPDA-------------LC--ESIFGA---GS---HNAPT-----FCYEE
IQIHTDRFGNCGKNSA------------------NKYIFCGWRNILCGRVVCTFPHQTPF
QQD--N---GDVIYAYV----R-NHLCISL----------------DP-RLHP-------
---------GMEDPLTIQIGSACDFG---------RVCSS--KRVCENTEL-LTNPADEC
T-EKCNG-RGVC-----NS--LGE-CNCTGGYL-PP----------TCES----------
-LR---GATRSMPPVG-----KG-------------------------------------
--------------------LITE-K--H-S-GK-------SKKRWLLGFYIFLPI----
--LIVP---------TIVA-LAWNRL------KKRF----T--KEEESLSSRS-------
-RSEESTHT-------YASTTRSESGTQ---------------------------ADTS-
-----------------------------------------------RSKSQDSA-----
-------QTHSS------------------------SN----------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------VVVEA-G---AFTRIT

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

F
L--LLWL-----------GISL--------P-FS------GL-----F-K-AEPS-QHQT
SPEVVIPLRVTSKGR-----GA--------GSPGW-LSYSLRFGGQRHVVHMRV-K----
----R-LLISTHLPVFT--YSEQHALQED---HPFV------------------------
----PEDCFYHGFVEGERES-LVALSTCYG--GF----R--GMLKVNDLMYEIEPMR-HS
-TTFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

SQISSD-ET--HSQYIKCGLKEED-I-----PHQHLEF-E-KA-----ENPP
LK-------QNPADDWWTHTF

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

FLELFVVADLDFFTYSQS-NFSKVQEDIVLVVNIVDFMY
QKLSVCVIL------IGIEVWNQGNAFL-MR------NMRQILEDFSQWKQIRLS--QLQ
-HDAAHIFI----KNSL-----MP-ILGL------AY--VAGICRPP-RDCGVCNF----
QGDTW-SCFANTVAHE-LGHILGM-QH--DE-----------EFCFC--GE-PGCIMSTL
KVP---ADRFTNCSYADFMN---TSSQQG--SCLHD--IP-R--PEKV---FL----LKR
CGNGIVER--EEECDCGSI-K---QC-EQ---DPCCLL-DCKLKP-GAACAFG------L
CCK--DCKFMPPGEVCRQKVN-ECDLPEWCNGTSHQCPEDRYVQNGIPCSD---NGYC--
---YEKRC-NNHDQ-------------QC--REIFGK---GS---KSASQ-----NCYKK
INTEGNRFGHCGKN-------------------GTVYLKCNPSDIFCGRVQCENVESIPN
LQD--KS---AVQLTHI----D-GVTCWSF----------------EH-YLGMG------
-------T---PDIGEVKDGTVCGTG---------KICIH---KKCVNISV-MSQ--ICL
PE-TCNN-KGIC-----NN--KHH-CHCGYGWS-PP----------HCLH----------
-RG---YGGSVDSGPATS---QRTALLL--------------------------------
-------------------------------------------------P--FGII----
-SLSVLIV---------FLIAGLC------MYFLKP----FG-LKTAA----SSG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
R--LWLLL-------AGLCGLL--SS--------------------RP-----GFQN--S
LLQIVIPEKIQTNTN-

PF01562 // ENSGT00910000144019_0_Domain_1 (257, 429)

-DSSEI--E-------YEQ-ISYIIPIDEKLYTVHLKQ-R----
------YFLADNFMIYL--YNQ-GSMNTY---SSDI------------------------
----QTQCYYQGNIEGYPDS-MVTLSTCS---GL---R---GILQFENVSYGIEPLE-SA
-VEFQHVLYKLKNE-DN-D-IAIFID-------R----SLKE-Q-P-M-D------DNIF
IS-----EKSEPA-VPDLFPLYLEMHIVVDKTLYDYWGS-DSMIVTNKVIEIVGLANSMF
TQFKVTIVL------SSLELWSDESKIS-TV-----GEADELLQKFLEWKQSYLN---LR
PHDIAYLLI----YMDY-----PR-YLGA------VF--PGTMCITR-YSAGV-AL---Y
PKKITLEAFAVIVTQM-LALSLGI-SYD-DP-----------KKCQCSE---STCIMNPE
VVQSNGVKTFSSCSLRSFQNFVSN--VGV--KCLQN--KP-Q--MQK---KSP--K--PV
CGNGRL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

EG--NEICDCGTE-A---QC-GP---ASCCDFRTCVLKD-GAKCYKG------L
CCK--DCQILQSGVECRPKAHPECDIAEYCNGSSPECGPDITLINGLSCKN-NK-FIC--
---YDGDC-HDLDA-------------RC--ESVFGK---GS---RNAPF-----ACYEE
IQSQSDRFGNCGRDRN------------------NKYVFCGWRNLICGRLVCTYPTRKPF
HQE--N---GDVIYAFV----R-DSVCITV----------------DY-KLPR-------
---------TVPDPLAVKNGSQCDIG---------RVCVN--R-ECVESRI-IKASAHVC
SQ-QCSG-HGVC-----DS--RNK-CHCSPGYK-PP----------NCQI----------
-RS---KGFSIFPEED-----MG-------------------------------------
--------------------SIME-R--ASG--K-------TENTWLLGFLIALPI----
--LIVT---------TTIV-LARKQL------KKWF----A--KEEEFPSSES-------
-KSEGSTQT-------YASQSTSEGSTQT-----YA------S---QTRSESSSQADTSK
S---------KSEDSAEAY--------------------------TSRSKSQEST-----
-------QTQSS------------------------SN----------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RQAEA-R---VTLRAPL
L--LLGL-----------WVL--L

PF01562 // ENSGT00910000144019_0_Domain_1 (205, 428)

TPVQCSQGHP------SW-----H-Y---------A
SSEVVIPRKETHHGK-----DL--------QFLGW-LSYSLHFGGQRHIIHMRR-K----
----H-LLWPRHLLVTT--QDDQGALQMD---DPYI------------------------
----PPDCYYLSYLEEVPLS-MVTVDMCCG--GL----R--GIMKLDDLAYEIKPLQ-DS
-HRLEHVVSQIVAE-PN-ATGPTFRDGDNEE--T------DP-LFS---E----ANDSMN
PR--------ISNSLYSSHRGNIKGHVQCSNSYCRVDD--NITTCSKEVVQMFSLIDSIV
QNIDLRYYI------YLLTIYNNCDPAP-VN------DYRV-QSAMFTYFRTTFFD-TFR
-VHSPTLLI----KEAP-----HECNYEP------Q---RYSFCTHL--GLLHIGT----
LGRHY-LLVAVVTAQT-LMGSTGE-KY---------------------------------
------------------------------------------------------------
--------------------C------------YCCRS-DCRLTP-GSICHIG------E
CCT--NCSYSPPGTLCRPIQN-ICDLPEYCHGTTVTCPANFYTQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1094)

DGTPCTE---EGYC--
---YHGNC-TDRNV-------------RC--KVFFGV---SA---EEAPE-----VCY-D
INLESYRFGHCTRQQT-----------------ALNNQAFAGIDKFCGRLQCTNVTHLPR
LQE--H---VSFHHSVR----G-GFQCFGL----------------DE-HRA--------
--------TDTTDVGYVIDGTPCVHG---------NFCNN---TRCNATITSLGY--DCR
PE-KCSH-RGVC-----NN--RRN-CHCHIGWD-PP----------LCLR----------
-RG---AGGSVNSGPPPK---RTRSVKQSQ------------------------------
---------------------------------------------QSV-MYLRVVF----
-GRIYTFIIA----LP-FGMATNV------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
P--LLFIL-------GELAMLL--A---------------------

PF01562 // ENSGT00910000144019_0_Domain_1 (227, 429)

RL-----DSEG--I
CLHITVPQKIEPRE-----GGA--A-------EGK-VTYVITIDGKPYSLHLRN-H----
------SLLSQNFLVYT--YNETGSLYSD---SSHF------------------------
----LAHCHYGGYVGEVPNS-IVTLSICS---GL---R---GFLQLENVSYGIEPLE-SS
-ARFEHIV

ENSGT00910000144019_0_Linker_1_5 (429, 503)

YQVKSN-S-----SVLAGN----D-S----HVWH-TD--Q-L------DKGH
FN-------EQDKNHSQLLPQS

PF01421 // ENSGT00910000144019_0_Domain_5 (503, 755)

LKLHIIVGKFLFDYMGS-DIMAITQKIFQIIGLVNAMF
TQLKLSVVL------ASLELWSDKNHIS-TD-----GNATDILQRLLDWKRDYLT---LQ
SNEITHLLI----YRRH-----PK-YIGA------AS--PGEICSKS-YVAGV-GM---Y
PEDIGLEGFSVVITQL-IGLHIGL-TYDDDI-----------SNCSCPS---APCIMQQG
ALSSSGRKTFSNCSLHDYMHYVSK--FDT--QCFGD--PS-N--VHVL-QPKQ-----AV
CGNGIMEA--GEECDCGNE-T---EC-QF---KECCDHETCRLKG-SAQCGSG------A
CCM-PTCELSAAGTPCRKAVDPECDFTEYCDGSSSHCVPDTFALNGHLCRL-GS-AYC--
---YNGRC-QALND-------------QC--VSLFGK---GS---QGASY-----ACFEK
VNSPRENLANCDSKN-------------------SYSVPCGQQDVLCGKLACFRPSKN-F
KSP--S---QSVVYSYV----H-DSVCLSV----------------LP-GLSMR------
--------SDGRDSAYVADGTVCGPQ---------MYCIN--G-TCKEVNY-TGN--DCN
ATKKCKG-NGIC-----NN--FGN-CQCFPDYR-PP----------DCNL----------
-QI-GSPGGSIDDGNILR---TE-T-----------------------------------
--------------------AFAT-K---RLSKN-------EDSWVILGFFIFLPF----
--IITF---------L-LGIMKRNER------KIVP----Q---GEHKI-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MMVVEA-G---AFIRVPF
L--LFWL-----------GVPL--------S-SF------SF-----F-Q-A

PF01562 // ENSGT00910000144019_0_Domain_1 (233, 429)

GPS-QRLS
SPEVVIPLKVTSRGR-----GA--------KAPGW-LSYRLRIGGQRHIVHMRV-K----
----R-LLVSTHLPVFT--YTEQHGLQED---HPFV------------------------
----PDDCYYHGYVEGAPES-LVALSICSG--GF----R--GILRVNDLTYEIEPIV-YS
-TTFEHLVYQVGSD-ET--QSQYMKCGLTEED-T-----AYQRLEF-E-KA-----KNSP
LK-------QNSAGNWWTHTLFLELFVVADHDFFTYSQS-NISKVQEDILLVVNVVDFMY
QKLNTCVIL------IGIEVWNQRNAFP-MR------NINQILEDFSQWKQIRLS--KTQ
-HDAAHIFI----KNSL-----IS-VLGL------AY--VAGICRPP-LDCGVCNF----
QGDTL-SYFANTVAHE-LGHILGM-RH--DE-----------KFCFC--GE-SGCVMSTF
KVP---ADRFTNCSYTDFMN---TTSQQG--SCLHG--IP-R--LEKV---FI----LKR
CGNGMVEG--EEDCDCGSL-Q---QC-EQ---DPCCLL-NCTLRP-GAACAFG------L
CCK--DCKFMPSGKVCRQQVN-ECDLPEWCNGMSHQCPEDTYVQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

NGIPCGK---SAYC--
---YEKRC-NNHDQ-------------QC--REIFGK---GA---KSASQ-----NCYKE
INTQGNRFGHCGTN-------------------GTAYLKCNTSDIFCGRVHCENVDDIPH
LQD--TS---ALQLTHI----N-GVTCWSI----------------QH-RFELG------
-------K---PDIGEVKDGTVCGTG---------KICIH---RKCVNLSV-LSQ--ICL
PE-ACDK-KGIC-----NN--KHH-CHCGRGWS-PP----------NCLH----------
-RG---YGGSVDSGPAAS---ERRAFLP--------------------------------
-------------------------------------------------L--LVII----
-SLSVSVV---------FLAAGLF------LYFQKP----F-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLVLF-------TGLSGLQ--A---------------------GQ-----NPRK--T
ILQTTVP

PF01562 // ENSGT00910000144019_0_Domain_1 (248, 429)

EKISSPDV----EKD--P-------ENN-IVYLIMIAEKPYFVHLKK-Q----
------SLLAPAAVAYT--YDENGVRQSQ---SLSP------------------------
----LESCTYSGYVAGFPNS-LVTLGICS---GL---R---GTIQFQNISYGIEPVE-AM
-SGFVHVVYESTNE-NT-E-IPVFEDN----E-S----YNWY-NE--S-Q------LELR
SN-------AKKTAFVNLSPRYIEMNLVVDKQLFDYMGS-DTKIVIQKVIQIISLVNTMF
FKLKLTVMI------HSIEIWSKENRIS-FP-----EDPKNLLIAFLNWKQ---N---K-
LQHVSYLLA----FKKY-----PA-SIGA------LY--PGNLCRAD-FDGAV-AL---Y
PNGLSLESYSVIVAQL-LSIGMGL-TYD-NT-----------DTCHCTG---DVCLMTPK
AIYFEGMKDFSTCSLDEFKYLSTG--RDL--GCLQD--WP-V--ERK---PRRRPR--RI
CGNGVL

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 878)

EG--NEQCDCGTL-K---NC-TH---RACCDPMSCRLKP-KAICGSG------E
CCK-QDCTIKPVNTLCRKPVD-ECDFEEYCNGKHSYCVPNTYSRDGQYCDS-GG-AFC--
---YHGAC-KTTDK-------------QC--MALLGK---GV---RGAPF-----WCFEE
MNSRGDRFGNCVSR------------------------LCKFQNVLCGKLVCTWPYKKLV
RLA--N---MSAAYTHV----R-DDICVSL----------------YK-GGRIP--KQ--
-TMTSYSSLEERDETFVEDGIICGPD---------MYCMS--A-ECKEARF-LTDY-TCD
ANRDCNS-HGVC-----NN--LQH-CHCDKGYK-PP----------NCEQ----------
-MP-G-HFGSIDDGHTSH---FQAP----L------------------------------
------------S---NYLKDLPP-R---KRALW-------NN-HEKLEF----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--LFLVL-------SCLGQLI--TA--------------------DQ-----DSET--P
LLRIIVPQKIES

PF01562 // ENSGT00910000144019_0_Domain_1 (253, 429)

NIK---DAKE--P-------ETH-VSYLIRIEGKAYTFHLEK-Q----
------SFLHPRFLAYL--HTKLGTLQPH---SSLM------------------------
----KGHCFYQGHAAEIPAS-TVTLSTCS---GL---R---GLLQLENITYGIEPLE-SS
-ATFEHMI

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YQVKNN-KI-D-YSPLKET----V------SPQH-ES--P-S------YRIL
VK-------PEKGSNITLMKR

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

TLNVKIVMDKAMFDHMGS-KMELAIQKVVHIFGLINTMF
SQLKMTVML------TSLEIWSDENKIE-TH-----GDADEVLQRFLLWKQKQPP---ES
TKAITYLLL----YKDY-----PD-YVGA------TY--HGMVCDPK-FTAGI-AL---H
PKTLTLEGFAAVLSQL-LGISLGL-TYD-DV-----------YNCFCPG---STCIMNPL
AIRSQGIKVFSSCSIDGFKQLASQ--SGL--DCLRD--KP-E--PQVV-SEPQT----QK
CGNRILEA--PEECDCGLE-E---NC-TH---KKCCNPEDCTLIK-PAECGTG------A
CCDKRTCKLAERGRPCRKSKD-LCDFPEFCNGFSEYCVPDTKAADLEPCNN-KT-AYC--
---FGGIC-RDLDR-------------QC--MDLFGK---HA---KGPNY-----LCMQE
VNSHNDKFGNCHG-------------------------RCSYSALFCGKVACYWNHEEIV
P-T-QK---YDLQYTYI----G-GQVCISA----------------HS-RHS--------
----------GPDDTYVFDGTICGGG---------KACIK--G-QCLRVHA-YRGQLKCD
SEVKCQG-QGVC-----NN--MNN-CHCEAGFS-PP----------ECDM----------
-TP-SSPGGSLDDGFWLP---LD---KS--------------------------------
------------------TPLIVK-R---R-DGR-------YKKGLLISFYVFLPF----
--LIMF---------A-IMVVRQNIS------KGFW----H---KE--------------
----EAAIG-------GSI-----------------------------------------
--------------------------------------------------SEGSN-----
-------QS---------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------ML

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

S
L--LLLLL-------IGLSGLQ--T--------------------------DHYPEK--L
RVQITVPEKIRSKIS----EG---V-------ESQ-VSYNIVIEGKKYTLNLTQ-K----
------DFLPQDFRVYG--YNGTGSMKPL---EPNF------------------------
----QNLCNYQGFIEGFPNS-VVIVSTCT---GLR------GLLQFENVSYGIEPLE-SS
-IGFEHVIYQVKHK-NA-G-VSLYAE----KD-I-------D-SRD-M-P------YKIQ
SI-------EPV----SDFSRFIEMHVVVEKNLFDHMGS-DTAIVTEKIFQLIGLINAIF
TSFNVTVIL------SSLELWIDENKIS-TA-----GDANELLHRFLTWKRSYLV---LR
PHDVAFLLV----YREN-----SD-YVGA------TF--QGKMCDSK-YGGGV-AL---H
PKTISLESLAVIIVQL-LSLSMGI-PYD-DS-----------SRCQCSG---AVCIMSPE
AILTSGMKIFSNCSMEDFARFMSE--PKS--QCLQN--QP-H--LGPS-YK-----V-AV
CGNGEV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 883)

EQ--GEQCDCGSA-E---DC-AAQS-TPCCSSGTCTLTP-GSQCAHG------E
CCH--NCNFKVKGEVCRSAMD-ECDLNEYCNGSSAACQEDLFIQNGHPCGG-NQ-WIC--
---LDGKC-MDGMK-------------QC--SSIFGE---GT---GFGSQ-----ECYTE
INSRADRSGNCGLTPG------------------G-YTACKSKDLQCGKLICDYKRDTIF
KTR--E---AIALYSNV----R-GRTCVTL----------------EY-SSDH-------
---------PKSQLMWVKEGTICGQN---------KVCKN--K-ECVDSTY-LNY--DCT
PE-KCNS-QGVC-----NN--KKN-CHCNPTYL-PP----------NCQY----------
-AHESWIGGSVDSGNFPP---TIP------------------------------------
-------------------GLTG--R---SYIEFD-YH----AKPTKWPFFLLIPF----
--FIVL---------C-VLIAALVKVNIQ---RKKW----R---SEDYTSDEQ-------
-LESDSEPK-------E-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------CYA------S---FDGICNPN-WGAMFVYI----
MRYHL-FRGACVTAHA-LGHNMGL-TH--DS-----------VGCYCFRR--TDCLMAPV
PDL---NDMMSNCSYEIIQRN--------------A--PN-V--PYTN-FPYV----APR
CGDKIKNQ-

PF00200 // ENSGT00910000144019_0_Domain_7 (790, 880)

-REECDCGSL-K---DC-AS---DRCCET-SCTLSL-GSVCNTG------L
CCH--KCKYAAPGVVCRDLGG-ICDLPEYCDGKKEECPNDVYIQDGTPCSA---VSVC--
---IRGNC-SDRDM-------------QC--QALFGY---QV---KDGSP-----VCYQK
LNRIGNRFGDCGVILRRG---------------GSRPFPCEEDDVFCGMLHCSGVSHIPG
GGE--HTTFHNILVHDI----K-EEKCFGY----------------EA-HQG--------
--------TDLPEMGLVVDGATCGPG---------SYCLK---RNCTSYQD-LHF--ECD
LK-TCNY-RGVC-----NN--KKH-CHCLHGWQ-PP----------TCEL----------
-RG---KGGSIDSGPPPD---KQYHITASA------------------------------
-------------------------------------------LANIN------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MSVV---ALLKDSANILLYLWKSQVA
LEEV------------------------KIKFQTWAPQKWNL-RLGLV-PGP-SCIRLEI
---LM-------------LLVIFVPSMYCHLG-----------------------STYYS
FYEIIIPKRLTVQGG------D--------SP

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

VEG-LSYLLFMQGQKQLVHLKV-K----
----R-SHFVNNFPIYS--YHN-GILGQE---SPFI------------------------
----SHDCHYEGYIEGVSGS-FVSVNTCA---GL----R--GILIKEEKSYSIEPVD-SS
-RRFEHVLYTMAHE-------ARVSCGVTSR-DSHVVSTSWQ-QG----------SRKPH
DL-------QAL-SYLWSHTKYVEMFVVVNNQRFQMWGS-NINETVQRVVDVIALADSFT
RGINTEVVL------AGMEIWTEGDLID-VA-----VDLQITLRNFNRWRRETLFH-RAK
-HDVAHMIV----GHHP-----GQ-NMGQ------AF--LSGACSSG-FAAAVESF----
HHEDV-LLFAALMVHE-LGHNLGI-QH--DH-----------SACFCKE--KHFCLMHEN
ITK---ESGFSNCSSDYFHQFLRE--HKG--ACLFN--KP-W--PRGRKRR------DSA
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ED--TEQCDCGS------AC-HL---DPCCDP-TCTLKE-HAECSHG------L
CCL--DCTFRRKGFLCRPTQD-ECDLPEYCDGSSAECPADSYKQDGTLCDR---IHYC--
---SGGQC-KNPDN-------------QC--VNIYGY---PA---RSAPE-----YCYIS
MNTRGDRFGNCGRPAE-D---------------QQTYVTCSDDNVFCGKLVCTGVQSLPR
VKA--QH---TVIQVPH----D-NDWCWSM----------------DADNI---------
--------TDIPDDGDVHVGTSCAPN---------KVCTD---YSCVHHSI-LLY--DCR
PKESCHG-KGVC-----NN--LRH-CHCEPGFA-PP----------DCKN----------
-PG---NGGSVDSGPPGM---QITN---N---SESGSE----SIARVQHQ----------
-------------------------R---QDVD------------YKL-VVLLVPL----
-FLVLLLCT-----LL-TISYLCSEVQT-----------AVA-EVEESSTETTL------
ESELTSADLV---PIAEEILPPDEEAPPPGEEAPQPG----EETVPPGEETVPPGE----
--------------------------ET--------------------------------
-------V--PPGEAPPAAEAPPA-EAAPPAE-----AAP----PPEAAPPPEAAPAPEA
-------APAPEAAAPPQAPPPE--------------------------APPA------Q
---------------------------------------------

------------------------------------------------------------
----------------------------------MSVL---ALLKDSANILLYLWKSQVA
LEEV------------------------KIKFQTWAPQKWNL-RMGLV-PGP-SCIRLEI
---LL-------------LLVIFVPSMHCHLG-----------------------SIYYS
FYEIIIPKRLTVQGG------D--------SS

PF01562 // ENSGT00910000144019_0_Domain_1 (273, 429)

VEG-LSYLLFMQGQKHLVHLKV-K----
----R-SHFVNNFPVYS--YHN-GILGQE---SPFI------------------------
----SHDCHYEGYIEGVSGS-FVSVNTCA---GL----R--GILIKEEKSYSIEPMD-SS
-RRFEHVLYTMAHE-------ARVSCGVTSR-DSHVVSTSWQ-QG----------SRKPH
DL-------QAL-SYLWSHTKYVEMFVVVNNQRFQMWGS-NINETVQRVVDVIALANGFT
RGINTEVVL------AGMEIWTEGDLID-VA-----VDLQITLRNFNRWRQEMLFR-RAK
-HDVAHMIV----GHHP-----GQ-NTGQ------AF--LSGACSSG-FAAAVESF----
HHEDM-LLFAALMVHE-LGHNLGI-QH--DH-----------SACFCRE--KHFCLMHEN
ITK---ESGFSNCSSDYFHQFLRE--HKG--ACLFN--KP-R--PRGRKRR------DSA
CGNGVVED--TEECDCGS------AC-HL---DPCCDP-TCTLKE-HAECSHG------L
CCL--DCTFRRKGFLCRPTQD-ECDLPEYCDGSSAECPADSYKQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTLCDR---IHYC--
---SGGQC-KNPDN-------------QC--VNIYGY---PA---RSAPE-----DCYIS
MNTRGDRFGNCGHPTE-D---------------QQTYVTCSDDNVFCGKLICTGVQSLPR
VKA--QH---TVIQVPH----D-NDWCWSM----------------DADNI---------
--------TDTPDNGNVHVGTSCAPN---------KVCMD---YSCVHHSI-LLY--DCR
PEESCHG-KGVC-----NN--LRH-CHCESGFA-PP----------DCKN----------
-PG---NGGNKASSHENY---KLGKMSS--------------------------------
-----------------------------------------------A-RGLIVML----
-GWCAILNS-----S----HRVLSDKE-------------SF-EERRVENEGKS------
----------------SAGIRGWA-------------------NQGEGTLGR--------
------------------------------------------------------------
-----------RS-----------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAGGET-P---VYVRISL
L--LLRL-----------GVFL--------F-LS------GS-----S-S-IEHS

PF01562 // ENSGT00910000144019_0_Domain_1 (236, 429)

-QHHG
LPEVVVPLKITYAGS-----SM--------KPPGW-LSYSLRFGGQRHILHMKV-N----
----K-LLFSKHLPVFT--YTDQHGLTED---QPFV------------------------
----QNDCYYQGYMEGDPES-LVALSTCLG--GF----Q--GTLQIHNVVYEIKPKR-LS
-TSFEHLLYKMVD--ET--ELPPKRCGLTDEE-I-----ARQ-LKFLQ-ES-----VNYT
LK-------QSGYVGWWTHRRFLELAVLVDHGRYLYHQS-NSSSVQSEVCMVVNGIDNFL
HSLDVNVVL------IGIEIWSEDNLLP-TT------NISILLEEFCMWKGRSFNT-RLP
-HDIAHVFI----KENY-----GR-LLGL------AY--VGTVCNQL-YNCGVDSF----
LNDKL-HEFAYIVSHE-IGHNLGM-RH--DD-----------KTCEC--GS-RKCIMFPS
KTV---ATRFSNCSYASYWN---VV-GKV--RCMHI--SP-N--PENI---FR----QTR
CGNSVLEE--GEECDCGST-Y---TC-AK---DPCCQS-DCTLRV-GATCAFG------L
CCE--NCTFMPSGSMCRKEEN-ECDLPEWCNGTSYQCPEDVYMQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1097)

DGTSCTG---GGYC--
---YEKRC-NDRNE-------------QC--RKIFGK---EA---KNANE-----NCYKE
VNMRGDRFGNCGLT-------------------ASSYIQCGIPDILCGRVQCENVTEIPL
LRD--HS---TVHWTRI----N-GVSCWGT----------------DY-HLGMT------
-------I---PDIGEVKDGTECGAN---------HICIE---RKCTFMPS-FES--GCS
PE-TCNM-NGVC-----NN--REH-CHCNSEWN-PP----------HCQE----------
-KG---AGGSVDSGPPPG---RDDVQD---------------------------------
-------------------------------------------HHYLLLF-RLIPL----
-FFM--L----------FCLL---------MWLFKK---LKE-LIGQEEKSAPAEP----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------M

PF01562 // ENSGT00910000144019_0_Domain_1 (279, 429)

YAIKIDRKTYTVHLEI-Q----
------SFLDPHFLVYA--YNKSGVLYPD---SSFT------------------------
----KGHCFYQGYTAEIPKS-VVTLSTCS---GL---R---GLLQLENVSYGIEPLE-SA
-VAYEHMLYQINND-KV-D-FSPLQEN----Y-S----ITQL-VD--Q-S------YRIL
VK-------SEKDSDT-LLNRFLKIQIIMDKALFDYMGS-EVPGTVEKVVHIFGLINAMF
SQLKVTVKL------TSLELWSDQNKIS-TN-----GDADEVLQRFVSWKEKSLF---QR
SRDMAYLLI----YRDH-----PN-YVGA------TY--HGMACNPK-FAAGI-AL---Y
PKMITLEAFSVVMTQL-LGVNLGL-TYNNDI-----------LTCYCPG---TTCIMNPE
AIRSHGVKFFSSCSMNEFNRMVSQ--PEF--ECLQN--QI-V--SEVS-YQDKN----TL
CGNGILEP--PEECDCGRS-Q---PC-KF---EKCCDTEHCTLIE-PAECGTG------P
CCDKNTCLLSVKGTICRQSQD-LCDFPEFCNGTSEFCVPDVISA

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1071)

DLQPCNN-NT-AYC--
---FQGIC-QDTDR-------------QC--AELFGK---FA---KGSTS-----LCTQE
VNLQEDDFGNCGRK------------------------YCNFKDILCGKIVCHWTRLEVI
PFK--K---FDVQYTYV----E-GHVCISA----------------YL-RIPTA------
--------HVTDDITYTANGTMCGPN---------MFCDR--G-RCTPKDS-YSKRVNCD
SVTNCSG-HGVC-----NN--LLH-CHCDVGYT-PP----------YCKP----------
-SP-LSPGGSIDNGFWSK---GSGDE----------------------------------
-------------------YL-FI-K---QHVAS-------RKHGLLFGFYIFLPF----
--LILI---------A-ILAFKWNKI------Q-LW----N---REGIANKGY-------
-ISEDSS-S-------NSNLS---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------L-RRART-A---PRASSGR
L--TLKAT-VAG--TDSLGNRA-------CHEGG------

PF01562 // ENSGT00910000144019_0_Domain_1 (221, 429)

ED-----P-P---------L
PPEITIPKKLSFRGG-----EQ--------RAARH-VSYLLQVKGKNRVLHLWP-K----
----R-FLLPRNLQVFS--FTEQGSLLED---HPYV------------------------
----PKDCNYMGLVEGNPDS-EVTISTCMG--GL----R--GILKIAAYHYQIEPRK-AS
-SNFEHMV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YPLEKE-E---EIPNQICGLTDDE-T-----VEQ-MAQ-R-ENM--A-----
-R-------SPDFTESYVHQ

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYLELALVFDNSRYLYLNS-NLTQVISDAILLTSIADSYF
QDVLMRIQL------LAVEVWTDRDKIR-LN----FPELSQVLGQFVWYRSRDLRL-RIP
-ADWAHLYV----HKKF-----KD-ALAH------HW---GSVCSMM-PSGSTSSV----
PDRNI-LGPATWTAHV-LGHSVGM-TH--DY-----------EYCQCEGR--HSCIMGTG
------RTGFSNCSYAEFYSHVS--SG-L--NCLNN--LP-G--LGY---V------VKR
CGNKIVEE--NEECDCGST-E---EC-KE---DRCCQP-DCKFKQ-GASCNAG------L
CCH--NCQFRPSGYMCRMEEN-ECDLAEYCNGTSAFCPSDTYKQDGTPCKY--E-AHC--
---FKQSC-QSRYM-------------QC--QKIFGL---DA---KDAPH-----QCYDA
VNVIGDQYGNCGIT-G-----------------VRKYKKCLKERSLCGRLQCINVETLPQ
MPD--HT---ILISTHL--HEE-NLMCWGI----------------GY-HLAMV------
-------PMGLPDLGVINDGTSCGKE---------RVCFN---RKCVNSSV-LNF--DCF
P-EKCNH-RGVC-----NS--NRN-CHCLYGWA-PP----------LCEE----------
-VG---YGGSIDSGPPGP---LKE------------------------------------
--------------------------------------G----VPVSVQ-VVSLMV----
-MRLTFVFIS----V--ILVLF--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MLSLTWGM-RLVER-P---VVPRVLL
L--LFAL-----------WLLL-LVPVWCSQGHP------TW-----R-Y---------I
SSEVVIPRKEIYHTK-----GL--------

PF01562 // ENSGT00910000144019_0_Domain_1 (271, 427)

QAQRL-LSYSLRFRGQRHIIHLRR-K----
----T-LIWPRHLLLTT--QDDQGALQME---YPFF------------------------
----PVDCYYIGYLEGIPQS-MVTVDTCNG--GL----S--GVMKLDDLTYEIKPLN-DS
-QSFEHLVSQIVSE-SD-DTGPMNAWKHWSHN-T------GS-PSS---R-L--EYADGT
PR--------LSSKNYATHPAAIKGHFQATHSLYSASGGDKLSSTVEYLFKVISLMDTYL
TNLHMRYYV------FLMTVYTNSDPFQ--L------EFAVPGGSAYNYYVSVFYN-KFK
-PDAGALLN----KHGP-----QDDQVNP------A---ERSICSSL--ALICIGT----
YDRNP-LFLSSIITNR-VGRSLGL-KH--DE-----------GYCVCQRR--NTCIMFRH
PQL---TDAFSNCSLAEISNILNT-PDLM--PCLFY--DR-H--VYYN-----TSLTYKF
CGNFKVDN--DEQCDCGSQ-K---AC-YS---DPCCGN-DCRLTP-GSICDKE------L
CCA--NCTYSPSGTLCRPIQN-ICDLPEYCSGSKFICPDDTYLQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 975)

DGTPCSE---EGYC--
---YKGNC-TDRNI-------------QC--MEIFGV---SA---KNANI-----KCY-D
INKQRFRFGHCTRAEE-----------------SLTFNAXXXXXXXXXXXXXXXXXXXXX
XXX--XXXXXXXXXXVL----P-ELSLHWLRII-----------RKCR-IKG--------
--------NSNYDVSQIL--------------------PV---EGCELSLVN--------
------------------A--REN-LRMNS------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MLSLTWGM-RLVER-P---VVPRVLL
L--LFAL-----------WLLL-LVPVWCSQGHP------TW-----R-Y---------I
SSEVVIPRKEIYHTK-----GL--------

PF01562 // ENSGT00910000144019_0_Domain_1 (271, 427)

QAQRL-LSYSLRFRGQRHIIHLRR-K----
----T-LIWPRHLLLTT--QDDQGALQME---YPFF------------------------
----PVDCYYIGYLEGIPQS-MVTVDTCNG--GL----S--GVMKLDDLTYEIKPLN-DS
-QSFEHLVSQIVSE-SD-DTGPMNAWKHWSHN-T------GS-PSS---R-L--EYADGT
PR--------LSSKNYATHPAAIKGHFQATHSLYSASGGDKLSSTVEYLFKVISLMDTYL
TNLHMRYYV------FLMTVYTNSDPFQ--L------EFAVPGGSAYNYYVSVFYN-KFK
-PDAGALLN----KHGP-----QDDQVNP------A---ERSICSSL--ALICIGT----
YDRNP-LFLSSIITNR-VGRSLGL-KH--DE-----------GYCVCQRR--NTCIMFRH
PQL---TDAFSNCSLAEISNILNT-PDLM--PCLFY--DR-H--VYYN-----TSLTYKF
CGNFKV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

DN--DEQCDCGSQ-K---AC-YS---DPCCGN-DCRLTP-GSICDKE------L
CCA--NCTYSPSGTLCRPIQN-ICDLPEYCSGSKFICPDDTYLQDGTPCSE---EGYC--
---YKGNC-TDRNI-------------QC--MEIFGV---SA---KNANI-----KCY-D
INKQRFRFGHCTRAEE-----------------SLTFNAXXXXXXXXXXXXXXXXXXXXX
XXX--XXXXXXXXXXVL----P-ELSLHWLRII-----------RKCR-IKG--------
--------NSNYDVSQIL--------------------PV---EGCELSLVN--------
------------------A--REN-LRMNS------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------VRIEDRTYTLLD---H----
------SFLQLFFFFFFVFKKIKKQSLPK---LSLK------------------------
---

PF01562 // ENSGT00910000144019_0_Domain_1 (364, 429)

-RGHCFYQGHAAEMPIS-IVTVSTCS---GL---R---GLLQLEDVTYGIEPLE-SS
-ATFEHMF

ENSGT00910000144019_0_Linker_1_5 (429, 513)

YEIKNN-KI-D-YAPLKEK--------------H-EN--Q-S------YRIL
VK-------PEVSNPFDHLH--------LCLT

PF01421 // ENSGT00910000144019_0_Domain_5 (513, 759)

FYDYMGS-EMGAATQKVVHIFGLINTMF
SQLKMMIML------TSLEIWSDKNKIS-TN-----GDADEVLQNFLSWKQKNANG-LQK
LNEMTYLLL----YMDL-----PA-YIGA------TY--RGTACNPK-FSAGI-AV---H
LRTLTIEALAVVLAQL-LGIHLGL-TYD-DV-----------YNCFCPG---STCIMNPE
AIHSHGIKIFSSCSMSEYKQLASQ--PES--ECLQQ--QQ-QQVLKVV-AQPQM----AT
CGNNKLEV--PEECDCGPA-E---TC-TH---VNCCDPKDCTLIK-SAECGTG------P
CCDKRSCLIAERGKLCRKSKD-LCDFPEFCNGSSEYCVPDTQAADLEPCNN-GT-AFC--
---YKGIC-RDPDR-------------QC--AELFGK---YA---KGSNY-----QCSQE
VNMQNDKFGNCRG-------------------------RCNSTSLFCGKIVCHWSSAKLV
H-R-KD---FDVQYTYL----G-GKVCISA----------------HI-KIH--------
---------GEEDLAYVADGTVCGDE---------EVCLQ--G-YCRSVHS-VPKHSNCS
SVEKCQG-HGIC-----NN--LDS-CQCEIGFA-PP----------ECDM----------
-TP-SSPGGSLDDGFWLP---ID---KS--------------------------------
------------------TPLIVK-R---R--GT-------YKKGLLISFYIFLPF----
--LLII---------A-VIVVKRRTS------KRFW----H---REALRMP---------
---------------------------------------------------KT--ILSLL
YRSVTEDS----------------------------------------------N-----
-------KVSN-------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LLALL-------AELGRLH--A---------------------RL-----DSEG--V
F

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 429)

LQVTVPRKIKSNE-----SEG--L-------EKQ-MIYIITIDEKPCTLHLRK-H----
------SFLSQNFLVYA--YSENGSLHAE---SSYF------------------------
----KMHCHYQGYIADFPNS-VATLSICS---GL---R---GFLQFENISYGIEPLE-SS
-AGFEHIIYQVKNN-NP-D-IPTLSEN----Y-S----DIWQ-KD--K-P------YKVH
LS-------SQKKTLSKLLPQYLEMHIIVEKALYDYMGS-EMMAVTQKIIQIIGLVNTMF
TQFKLTVIL------SSLELWSEKNQIS-AN-----GDADDLLQRFLAWKQDYLI---LR
PHDIAFLLV----YRKQ-----PK-YLGA------TI--PGTICNKS-YDADI-VM---Y
PDAITLEGFSVIIAQL-LGLKIGL-TYN-DN-----------NKCSCLR---ATCIMNRE
AVGSSGIKIFSNCSMHDYRYFVSK--SEA--KCLHN--FS-N--LQPL-YQNQ-----SV
CGNGILEP--NEECDCGSE-E---EC-QF---KKCCDYSTCKLKG-SVKCGSG------P
CCT-SKCEISVAGTPCRKSIDQECDFTEYCNGTSSNCVPDTYAL

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1074)

NGQLCRF-GT-AYC--
---YNGQC-QTTDN-------------QC--AQIFGK---GA---QGAPF-----ACFEE
VNSLRDRFGNSGFKN-------------------SQPLPCEQKDVLCGKLACVWPDKNTY
KSA--V---QSAVYSYI----P-GHVCISV----------------AT-GSSVR------
--------SDGRDYVYVADGTVCGAQ---------MYCVN--K-TCKGVHL-MGY--NCN
ATTKCKG-NGIC-----NN--LGN-CHCFPGYK-PP----------DCEF----------
-QI-DSPGGSIDDGNVQK---SG-E-----------------------------------
--------------------FFIK-K---GYDTH-------RNNWLILSFYIVLPF----
--FTIF---------T-IMIMKRNEM------RKSH----N---RENAEYEG--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------SSIMMVGEA-G---VYLRV

PF01562 // ENSGT00910000144019_0_Domain_1 (179, 429)

AL
M--LLWL-----------GVS-------------------DL-----S-H-AGSY-QRLS
SPEVVIPLKVTSRVR-----GA--------KLLGW-LSYSLHFGGQKYIVYMKV-K----
----K-LLVSRHLPVLT--YTDQRALLED---QPFV------------------------
----RDDCYYHGYVEGVSES-LVVFSACLG--GF----Q--GVLQINDLTYEIEPIR-HS
-TTFEHLV

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YKINSN-ET--QFPPMRCGLTEEE-I-----VRQRLEY-L-EA-----ENST
LK-------QNSIDAWWTHS

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

WFLELAVVVDNDFFIYSES-NFSKVQEDVLLIVSIVDSIY
QQLGTYVIL------MGIAIWNQENIFP-II------SIEQVLENFCHWKQISLS--RLQ
-HDAAHLFI----KYSF-----KN-VLGL------AY--VAGICHPP-IDCGVNSF----
QGDLW-SLFALTVAHE-LGHTLGM-QH--DE-----------EFCLC--EQ-RGCIMNAI
RMV---AKRFTNCSYAQFRK---TTLNQG--SCLHN--FP-R--PWEF---FM----LKR
CGNIVVEG--EEECDCGSV-Q---QC-EQ---DPCCLS-NCTLSP-GAACAFG------L
CCK--DCKFMPSGELCRQQIN-ECDLPEWCNGTSHLCPEDEYVQDGMPCSG---SAYC--
---YQKRC-NNHDK-------------QC--REIFGK---GA---KSASQ-----SCYKE
INSKGNRFGHCGIN-------------------GTTYLKCNTSNIFCGRVQCENVREIPH
LSE--HS---ALQHTLI----N-GVSCWSI----------------DY-HLGMD------
-------V---SDVGEVKDGTVCGPG---------NICIH---KRCVSLSL-LSQ--ICL
PE-TCNR-KGVC-----NN--KHH-CHCGYGWS-PP----------YCLH----------
-RG---YGGSVDSGPASA---KRRVFLP--------------------------------
-------------------------------------------------L--TVIL----
-TLSAFFL---------LLAVGLH------KYLQK---R-SG-PKET-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------S-

PF01421 // ENSGT00910000144019_0_Domain_5 (521, 760)

DIKAVTQKVIQIIGLVNTML
TQLKLTVVI------SSIEIWSHKNKFS-TL-----GDFDNILYQLLEWNYKDLN---MK
QYNIAYLFA----FREH-----PT-FIGS------TY--PREICNKK-YAVGV-AL---Y
IDGLSLESYAVIIVQL-LGLNLGL-TYD-NT-----------DICYCSG---DVCTMTPK
AVYSRGIKDFSTCSLDDFKYFVSR--NGL--SCLQN--NP-F--AKPV-YREEQ-K--AA
CGNGVLET--NEECDCGTK-Q---NC-TH---KLCCDASECKLKG-SAICGSG------K
CCT-EECKLKPVNTVCRQSVDEQCDFTDYCNGSHPLCVPDTYVRDGETCDS-GE-SFC--
---YGGVC-RSFDK-------------QC--ETLIGK---GL---LVRGA-----S----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MGET-L---AHIRITL
L--QLWL-----------ERLL--------F-FS------AW-----P-L-SGCA-QHTS
LPE

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

VVIPLRVTGTSR-----RM--------WAAGW-LSYSLHFGGQRHIVHMKA-K----
----K-FLVSKHLSVFT--YTDQGALLED---QPFV------------------------
----RSDCYYLGFVEGDPIS-TVALTTCFG--GF----Q--GILQVNNTAYEIKPQN-AS
-STFEHLIYKIDNE-ET--ELFPMRCGLTEEE-L-----ARQ-LKI-Q-AR-----YNFT
LR-------QSSYEGWWTHKRYLEVALVVDHQRYVFQQC-NISLVLSEVYLIVNVVNAIY
YTLDLDVIV------QGVEIWTEGNPVT-VH------DIDQLLTDFCIWKKINLDH-RLQ
-HNIAHLFV----EHNF-----GI-SLGL------AY--VGSVCMPS-LNCGVDRM----
VGSDL-FTLGRIMAHE-LGHNLGM-LH--DE-----------ASCTC--GE-SLCLMAPT
DNI---NIRFSNCSYGMFLK---TY-DTT--NCLHK--IH-R--PLSI---LR----VTF
CGNGVVED--GEECDCGSE-T---MC-RN---DPCCMK-GCTLKY-GAACSFG------L
CCK--DCQFMPSGTVCRENNS-ECDLPEWCTGTSHECPEDVYVL

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1093)

DGTPCHG---GGYC--
---YEKRC-NNRDQ-------------QC--QQIFGK---EA---RSAAQ-----TCYRE
INTQGDRFGNCGIS-------------------SHTYIRCNDSDVLCGRIQCENIADIPH
LKE--HS---TVHWHQF----N-DVTCWGT----------------DY-HFGMT------
-------I---PDTSIVKDGTSCGLE---------HMCLH---RKCVPKPI-WAS--NCS
PKTTCNM-KGVC-----TN--KQH-CHCNPGWD-PP----------YCMT----------
-GS---NGGSKDSTPEP-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ML
S--LLLIL-------SGLGRLT--SA--------------------GP-----HSET--P
VLQITVPRKI

PF01562 // ENSGT00910000144019_0_Domain_1 (251, 429)

QTNTN---DGDV--S-------ETH-ATYSIKIEGKPYTFLLEK-Q----
------SFLHPHFLVYL--YNESGTLYVD---SSFS------------------------
----KGHCFYQGYAADIPKS-AVTLRTCS---GL---R---GLLQLDNISYGIEPLE-SS
-PTYEHVV

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YRIKND-AI-G-HFSFQEN----Y-P----VAQH-ID--Q-S------YRIL
VK-------SDINSGAMLSKR

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 759)

TLKIQIIMDKAMYDYMGS-AVAVAVEKVFQIFGLINTMF
SQLNITVML------SSLEIWSDQNKIS-TS-----GHADEILQRFLLWKQKLLF---QR
SHDMTYLLI----YRNH-----ST-YVGA------TY--HGMACDPK-FATGI-AL---Y
PKKITVEAFSVVMAQL-LGINLGL-TYD-DI-----------YNCYCPG---PTCIMNPD
AIRSHGVKFFSSCSMDEFKQIVLQ--PEL--KCFQD--KT-I--SEMT-YQK-S----AT
CGNGILEP--TEQCDCGYR-K---AC-TY---KKCCNPADCTLIG-FAECGSG------P
CCNNKTCTIYARGHVCRKSID-MCDFPEYCNGTSEFCVPDVKAADLESCSN-KT-SYC--
---FKGIC-RDRDR-------------QC--SQLFGK---FS---KSANL-----LCTEE
VNFQNDKFGNCGQ-------------------------RCPFFDILCGKIVCHWIHSELV
PMT--D---LDIQYTYL----G-GHVCLSA----------------HA-RNASK------
--------QL---GTYTEDITACGQQ---------KVCHS--R-GCRYLSE-LNI---TK
CTTNCGQ-NGIC-----ND--RFH-CQCDPGYA-PP----------DCDP----------
-SM-SSPGGSIDDGFWLS---V---G-Y--------------------------------
------------------V-PLFP-K---QRAAP-------KNNGLLISFYIFSPL----
--LILI---------A-IVSLKWNKM------KRFW----S---KVGTVSSRS-------
-ISEDSSSN-------NSQSQS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSGRT-L---LPQGPSL
P--TLVLV-ALL--VGALGEDM-------IF-HP------EW-----G-F---------E
S

PF01562 // ENSGT00910000144019_0_Domain_1 (242, 429)

YEIIIPKKLSFRGG-----QQ--------GAVEQ-VSYLLQVKGKKYVLHLWP-K----
----R-FLLPRNLKVLS--YTEQEKLLED---HPYI------------------------
----PRDCNYVGSVEGTQDS-EATLSTCMG--SL----R--GILKIDEEHYQIEPLR-GS
-SSFEHVIYLLKEE-D---KFQNHTCGLTNDE-L-----EKL-IAE-N-ENM--A-----
-R-------RSDFYNSYKHQKYTEVAMVFDHSRYLFLQS-NVTRVIYDAILLIAVMDTFF
REIGMRLHL------QGTEIWTNEDKIN-IN----SMNSGEILDAFLRYRKIHLSV-QIP
-HDWGHLYI----SKTF-----VH-ANAI------GWSFVGGACVEN-YSGSVSTL----
TNINI-LAASRMSAHE-LGHGVGM-KH--DT-----------EFCQCRGR--RTCIMGTG
------SSGFSNCSYLWYFYHAH--TS-G--HCLNN--IP-G--LGY---V------LER
CGNKIVEG--NEDCDCGSR-E---EC-KK---DKCCQP-DCKFTE-GANCSTG------L
CCH--NCHFRPLGYMCREEDN-ECDLAEYCNGISNLCPNDSYKL

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1073)

DGTPCKH--N-SLC--
---FRKRC-RSRYV-------------QC--QNIFGP---HA---MEAPD-----QCYHA
VNLMGDQYGNCEIL-G-----------------VRAYKACTEANAMCGRLQCINVNTIPD
LPE--HT---IVISTHL--QAE-NLMCWGV----------------GY-HKAMI------
-------PMGIPDIGVINDGTRCGYN---------GLCIN---RTCVNDSV-LDF--NCF
P-QKCNH-RGVC-----NN--KKN-CHCMYGWA-PP----------FCEE----------
-VG---YGGSIDSGPARK---QKE------------------------------------
--------------------------------------E----VPTPVQ-VVSIML----
-VRLILLVIS----V--IVV--FFKRMIR-QYMQSK---QE-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MF
L--LVVLL-------TGVGGLY--A---------------------GH-----NPHK--T
FVQ

PF01562 // ENSGT00910000144019_0_Domain_1 (244, 429)

TTVPEKISSVDT----RRD--P-------ENN-VTYIITVKGKPYFVHLKK-Q----
------SFLSSASVVYS--YDKDGTQHSQ---PLLP------------------------
----QMDCSYSGYITGFPHS-VVTLMTCS---GL---R---GVMRIENISYGIEPLE-AV
-SGFMHMI

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YEENND-DT-H-VSLFGEN----D-T----FTWL-NN--T-E------NQVR
SS-------LHKTEFTKLFP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

RYIEMYIVVDKNLFDYMGS-DVKTVTEKVIQLIGFVNTML
TQLKLTVVI------SAIELWSNTNKFA-TT-----GHPDDVLFRFLEWKHQHVD---PK
PHHISYLLV----FEKH-----PT-LIGA------TF--PGYMCDKK-YDAGV-AL---Y
PMGLSLKSYAVIIVQL-LGLNVGL-IYD-NT-----------DTCYCSG---DTCTMTPK
AVYSGVLTDFSTCSLDNFKLFASH--YGL--HCLKN--NP-L--DKPI-YKQTNPK--KM
CGNSIREE--GEECDCGTA-L---NC-TH---VRCCDPTSCKKKG-SVKCGSG------E
CCT-TNCQLKKANTLCRSSIDTECDFNEYCNGNEGDCVPDTYARDGSHCDS-GE-GYC--
---FGGIC-RTFDR-------------QC--EALFGK---GS---KGAPF-----ACFDE
INSRGDRFGNCGRY------------------------HCEIQHALCGKLVCTWPHKTLI
SRE--N---LSVIYTHV----R-DDICVAG----------------AK-TDGKIIRTT--
-SFTTYLEPTDRDETFVEDGTICGPG---------MYCDK--W-VCRDVQH-LLN-SSCD
PELHCGG-NGIC-----NN--FQN-CHCNKGFS-PL----------ECQL----------
-KK-G-EFGSIDDGHMTK----GK------------------------------------
-------------------NA-LR-A---GYATS-------SKHRFQLIFYIAIPV----
--MMIA---------A-AILIKQNTL------RELY----C---RGGKEHESS-------
-VSEDRSSS-------IISSSIESNTPTD-----FE------S---NTMTDDVPKPSEVA
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------MFVX---XXXXXXXXXXXXXXXXXXX
XXXX------------------------XXXXXXXXXXXXXX-XXXXXXXXX--XXXXXX
X--XX-------------XXXXXXXXXXXXXX-----------------------XXXXX
XXXXXXXXXXXXXXX------X--------DPG

PF01562 // ENSGT00910000144019_0_Domain_1 (274, 429)

GK-VSYMLLMQGQKQLLHLEV-K----
----GHHYPENNFPVYS--YHN-GILGQE---MPLL------------------------
----SQDCHYEGYMEGVPGS-FVSVNICS---GL----R--GVLIKEETSYGIEPML-SS
-KNFEHVL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YTMEHQ-------PGVSCSVTPK-DS-PGDTSHP-PR----------SRKPD
DL-------LVL-TDWWSHT

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYVEMFVVVNHQRFQMWGS-NINETVQAVMDIIALANSFT
RGINTEVVL------VGLEIWTEGDPIE-VP-----VDLQTTLRNFNFWRQEKLVG-RVR
-HDVAHLIV----GHRP-----GE-NEGQ------AF--LHGACSGE-FAAAVEAF----
HHEDV-LLFAALMAHE-LGHNLGI-QH--DH-----------PTCTCGP--KHFCLMGEK
ISK---DSGFSNCSSDHFLRFLHD--HRGAGACLLD--EPGR--QSRMR-R------AAN
CGNGVVED--LEECDCGS------DC-DS---HPCCSP-TCTLKE-GAQCSEG------L
CCY--KCTFKKKGSLCRPAED-VCDLPEYCDGSTQECPANSYMQDGTQCDR---IYYC--
---LGGWC-KNPDK-------------QC--SRIYGY---PA---RSAPE-----ECYIS
VNTKANRFGNCGHPSS-A---------------NFRYETCSDEDVFCGKLVCTDVRYLPK
VKP--LH---SLLQVPY----G-EDWCWSM----------------DAYNI---------
--------TDVPDDGDVQSGTFCAPN---------KVCME---YICTGRGV-LQY--NCE
PQEMCHG-NGVC-----NN--FKH-CHCDAGFA-PP----------DCSS----------
-PG---NGGSVDSGPVGK---PDDRHLSLSFLAE--------------ES----------
-------------------------P---DDKMED--EE----VNLK-VMVLVVPI----
-FLVVLLCC-----LM-LIAYLWSEVQE-----------VVS---PASSSESSS------
SSSWSDSD-------S--Q-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M-RSAPT-L---LSRGRSL
P--VLVLA-TLL--IDSLGDDL-------IF-LP------EW-----G-F---------

PF01562 // ENSGT00910000144019_0_Domain_1 (240, 429)

D
SYEITIPKKLSFRAG-----KQ--------GAASP-LSYLLRLKGKKHVLHLRP-K----
----Q-LLIPPHLRVFS--FTEVGELVED---QPYM------------------------
----PRDCAYLGSVEESEDS-DATLITCMG--GL----R--GVLNIDAQQYQMEPLK-DA
-HHFEHVVYLLK-R-E---PSSNQTCGLTDDV-V-----EQQ-MRR-H-RPK--D-----
-A-------LRDYSESYKHQKYLELVMVFDQGRYKFVNS-NLSQVISDAILLTAIMDTYF
QEINVRITL------KALEVWTDFNKVY-LD----YPTLSEVLSRFLVYRRTDLYP-RLP
-SDWTHLYV----HRKY-----SD-ALAW------SW---GKVCSKI-GAGSVSTF----
LDENV-LGPATWTTHE-VGHALGM-QH--DE-----------EYCQCKGR--RSCIMGTG
------RTGFSNCSYIFYIKFIS--LG-A--NCLNN--IP-G--LGY---V------IKR
CGNKILED--HEECDCGSK-E---EC-RK---DLCCEP-NCKLKH-GANCSIG------L
CCH--ACGFRPSGYVCRQEEN-ECDLAEYCNGTSSFCPNDTYKQ

PF08516 // ENSGT00910000144019_0_Domain_9 (885, 1074)

DGTPCKY--H-GLC--
---FRKGC-RSRFM-------------QC--QSIFGP---DA---KEAPD-----QCYEA
VNLQGNQYGNCAII-G-----------------VSSYRKCDKENSICGRLQCINVKSIPD
LPE--HT---TIISTYL--QQE-NLMCWGT----------------GY-HLSME------
-------PLGIPDLGVINDGTSCGED---------RVCIN---RTCVNSST-LKF--DCL
P-EKCNG-RGVC-----NN--NKN-CHCMYGWA-PP----------FCEE----------
-MG---NGGSIDSGSPRR---TRS------------------------------------
--------------------------------------D----VSAPVE-VVSLMM----
-LRVILFAGS----L--VAV--FFRQVII-KCFTPN---LET-P-ISK------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------T-VLAE--------GQVML
L--LLGL-----------WVL--LDPGQCSPGRP-----

PF01562 // ENSGT00910000144019_0_Domain_1 (220, 428)

-SW-----R-Y---------I
SSEVVIPRKELHQGR-----GV--------QVAGW-LYYSLHFGGQRHVICLQS-K----
----K-LIWARHLLMMT--QDDQGALQMD---YPYI------------------------
----PTDCYYLGHLEDIPLS-TVTIDTCYG--GL----E--GIMKLDDLTYEIKPLK-DS
-NTFEHIVSQIVAN-RN-ATGPMYRLGHEED--F------DP-FFS---K----VNSSVA
PK--------LSSFNFMYHRAQMKGQVQIAHEVYTVLN--NISKCIQFAVNMFSITDSFL
RSLGFGHYI------FLLNIYNQREPIV-LN------DFRVPGGAIHAYYKATFHD-LYQ
-PYPSTLIT----KNAP-----NDD-QEP------H---RYGCCGHF--NLIIISS----
RGRHY-LLLAILAAHK-IGRQIGL-EY--DG-----------STCVCQRR--ATCLMRRF
PEI---TDSFSNCSFVHTQHIVSN-RYIS--KCYYL--PG-R--LYLN-----KTLLQTR
CGNSLV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 882)

EE--REQCDCGSF-K---HC-YA---NACCQS-DCRFTP-GSICDKQ------Q
CCT--NCTYSPTSTLCRPVMN-ICDLPEYCGGSTYTCPDNFYLQDGTPCTE---DGYC--
---YRGNC-TDRTM-------------HC--KEIFGE---TA---ENGPG-----DCY-A
INLNTFRFGHCKRVQT-----------------QNVYQACAAADKECGRLQCINVTHLPQ
LQD--H---VSFHQSVY----N-EFTCFGL----------------DE-HRG--------
--------TGSTDAGHVRDGTPCGEG---------LYCFA---SRCNMTMNNLHY--DCF
PE-KCNF-RGIC-----NN--NKN-CHCHVGWD-PP----------LCLS----------
-PG---AGGSSQSGPPPR---RMRTVTDSM------------------------------
---------------------------------------------EPI-VYLRVVF----
-ARVYCFIFA----LL-FGVATNVRTIK------T-----TI-VQEQTATEP--------
----Q-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------M

PF01562 // ENSGT00910000144019_0_Domain_1 (180, 429)

L
L--PVLLL-------AGLRGLL--AT--------------------GP-----DFQD--I
FLQIITPEKIQANIN---DSEV--E-------NEE-ISYIIPVDGKQYTIYLKK-R----
------YFLSENFMVYL--YNQ-GSMKAY---DSEV------------------------
----QTQCYYQGYVEGYTNS-IVILSTCS---GL----R--GILQFENVSYGIEPLE-ST
-IEFQHVL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YKLKNK-NN-D-SALLTSH----G-Q----GIKQ-N-S-V-N------YVIL
LS-----KKFQPA-FTNLIP

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

LYLEMHIVVDKLLYDYLGS-DSIVATKKVIEIISLINSMF
AQFKVTIVL------SSLELWSDENKIS-TA-----VKADALLHAFLEWKDSYLT---LR
PHDIAYLFI----YRDH-----PD-YVGA------TF--PGKMCVTN-YSAGI-AL---Y
PKEMTLEAFSVIVTQM-LGLSLGM-SYD-DP-----------KKCHCSG---AICIMNPE
ALRYSGVKTFSNCSLNDFGNFISN--MGA--RCLQN--KP-Q--LQI-----P--A--AF
CGNGKVEG--NEACDCGTV-A---QC-GP---NSCCEPRTCTLRH-GAQCGGG------V
CCR-PDCQFQSKGFECRPRAHPECDFPEFCNGSSAKCEPDVTVHNGHLCKH-GK-HMC--
---FGGNC-QDSNA-------------QC--EAIFGK---GS---RAAPF-----QCYEE
IHAQTGRFGNCGINN-------------------KDYVPCRWRNFRCGRLICTYPTRIPF
YKD--N---VAVMYAYV----R-DIICVTI----------------DF-RVPL-------
---------SAQDPMAVRSGTYCDKG---------KXXXX--X-XXXXXXX-XXXXXXX-
XXXXXXX-XXVC-----NS--LLK-CHCFDGFQ-PP----------TCKS----------
-KT---RAYSEVPEKQG----KS-------------------------------------
--------------------LLME-N--VFR-KT-------KKSWSLLSVYIVLPG----
--LVIA---------IIIF-VSWNRL------KKWF----V--KEEESLSSXX-------
-XXXXXXXX-------XXXXXXXXXXXXX-----XX------X---XSRSEPRNHTDTSR
L---------RSETS---------------------------------------V-----
-------QTETS------------------------SN----------------------
------------------------------------------------------------
---------------------------------------------

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MSEA------------------------IRALQTWAPHTKGL-RLAPV-PGL-SCARLGI
L--LF-------------LVLISLPSLYCDLG-----------------------SLHHS
SYEIVIPKSLTVEGR-----

PF01562 // ENSGT00910000144019_0_Domain_1 (261, 429)

-E--------DQVEK-LSYVLFMQGQRQLIHLTV-K----
----R-DYFVDNFPVFS--YHN-GILGQE---MPPV------------------------
----SQDCHYEGYIEGVPGS-FVSVNTCS---GL----R--GLLIKEEKSYGVEPVH-SS
-KRFEHVL

ENSGT00910000144019_0_Linker_1_5 (429, 501)

YAMAHE-------ARVSCGVTSK-DSQVASTSRR-PE----------SGKPH
SW-------QVP-SDLWSHI

PF01421 // ENSGT00910000144019_0_Domain_5 (501, 760)

KYVEMFVVVNNQRFQMWGS-DVKQTVQRVMDIIALANSFT
RGINTEVVL------AGMEIWTEGDLTE-VP-----VDLQVALRNFNSWRQENLFH-RVK
-HDVAHMIV----GQHP-----KE-DTGQ------AF--LSGACSSD-FAAAVESF----
HHEDV-LLFAALMVHE-LGHNLGI-RH--DH-----------SACICKD--RPFCLMHEN
ITK---ESGFSNCSSDFFHQFLWE--HKG--ACLFN--KP-G--HKGRLRR------AST
CGNGIVEG--DEQCDCGT------VC-SF---DQCCDD-TCRLKS-TALCNPG------P
CCN-ATCQYERTGRSCRPASG-ECDLPEFCLGTSGECPPDTYKQDGSGCMG---GYYC--
---VKGVC-MSSDA-------------QC--TEIFGF---PA---KAASE-----ECFRS
FNGKGNRFGNCGIPSK-S---------------GSAYTKCENDNVFCGKMICTNVQELPE
TQV--NY---TLLQTHY----K-DDFCWSM----------------DKYSV---------
--------RDVPDSGDTKKGNICAPG---------KVCMD---FTCSDVSV-LGY--DCD
VKVQCNQ-KGVC-----NN--KKN-CHCDDGFS-PP----------DCKN----------
-PG---AGGSVDSGYPGS---DNSEPEGG-------------------------------
------------------------------------------------TIIPLVAI----
-LCTLLLLF-----II-CCICMFCKADK-----------GAA-AEPKKEPAVPE------
EKPPEAKPPE---AKPPEAKPPEAKPPEEEAEE---E---EAEEEEEEEEEEEE-E----
--------------------------E--ESEP---------------------------
------------------------------------------------------------
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---------------------------------------------

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-----------------------MRCGLTEKE-V-----ARQQLEF-E-EA-----ENSA
LE-------PKSAGDWWTHAWFLELVVVVNHDFFIYSQS-NISKVQEDVFLVVNIVDSMY
KQLGTYIIL------IGIEIWNQGNVFP-MT------SIEQVLNDFSQWKQISLS--QLQ
-HDAAHMFI----KNSL-----IS-ILGL------AY--VAGICRPP-IDCGVDNF----
QGDTW-SLFANTVAHE-LGHTLGM-QH--DE-----------EFCFC--GE-RGCIMNTF
RVP---AEKFTNCSYADFMK---TTLNQG--SCLHN--PP-R--LGEI---FM----LKR
CGNGVV

PF00200 // ENSGT00910000144019_0_Domain_7 (787, 880)

ER--EEQCDCGSV-Q---QC-EQ---DACCLL-NCTLRP-GAACAFG------L
CCK--DCKFMPSGELCRQEVN-ECDLPEWCNGTSHQCPEDRYMQDGIPCSD---SAYC--
---YQKRC-NNHDQ-------------HC--REIFGK---DA---KSASQ-----NCYKE
INSQGNRFGHCGIN-------------------GTTYLKCHISDVFCGRVQCENVRDIPL
LQD--HF---TLQHTHI----N-GVTCWGI----------------DY-HLRMN------
-------I---SDIGEVKDGTVCGPG---------KICIH---KKCQQIKL-HPS--LPL
VL-VVFL-V-----------------HRDDLWEIYE----------MCLP----------
-QS---VQG---------------------------------------------------
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---------------------------------------------

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-----MLL-------AGLRGLL--TS--------------------RP-----DF

PF01562 // ENSGT00910000144019_0_Domain_1 (236, 429)

QN--S
FLQIVLPEKIQANTS--DNSEV--E-------NEQ-VSYSISIDEKPYTVHLKQ-S----
------FYLANNFMVYM--YNQ-GSMNSQ---SSNI------------------------
----QAQCYYQGYIEGYPNS-FVTLSTCS---GL---RR--GILQFENVSYGIEPLE-SA
-FEFQHLL

ENSGT00910000144019_0_Linker_1_5 (429, 502)

YKLGNE-KN-E-FAVLTEN----N-Q----DTEQ-N-P-M-D------HYIF
IG-----EKPESTVSTDLIPL

PF01421 // ENSGT00910000144019_0_Domain_5 (502, 760)

YLEMHIVVDKALFDYLGS-DSMIVTNKIIEIIGLVNSMF
AQLKISIVL------SSLELWSDKNKIS-TV-----GEADELLYRFLEWKNSYLT---LR
PHDIAYLFI----FREY-----PN-YVGA------AF--PGKMCVTG-YSAGI-AL---Y
PKEMTLEALSVIVTQM-LGLSLGI-SYD-DP-----------KKCRCSG---AICIMSTK
ALQSSGMKTFSDCSLRDFENFVSN--MRA--QCLQN--KP-Q--MQM----NP--G--PI
CGNGRVEE--NEVCDCGTE-E---QC-GP---DNCCNPQTCVLKP-DSECDKG------L
CCD--NCKFMAAGATCRPIAHPECDIPEVCNGSSGRCPADITILNGQQCEE-GK-AFC--
---YDGGC-QDIDA-------------HC--ESIFGKALTGS---KNAPF-----ACYEE
IQSQSDRFGNCGQEG-------------------LRYTFCPWRNLICGRLICTYPLETPF
LRD--N---ASVIYAFV----R-SIICITM----------------HY-ET-T-------
---------GIKDPLVVNNGSICDKE---------RICVN--R-QCLEVRP-FIDRVNRC
S-AKCNG-NGLC-----T------------------------------------------
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