Query Results 

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------------------------------------------------------------
-----MPPPRTKDARDHR------EHRRRAPDEEETREKWDWNCPETRRLLEDAFFSDEG
YIRQGSEECQRFWAFFERLQRFQSLRVPQS--EA-R----EPRHPCANV-PALADLPRTY
DARYRINLSVLD--P-EV-RG------SRELGRRPPPARVSEFRRALVHYLDFVQKQVFA
RLAKLQGERAALPIAQYGQRILQTLREHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSYESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPR
LPQYQVLIVDEVHERHLHNDFLLGIL-RRLLPQRPDLKVVLMSATINIALFSSYFGDAPV
VQVP-GRLFPIKVVYQPQEV-E--PATSKSEKLDPRPFLRVLEAIDKKYAPEERGDLLVF
LSGMAEISAVLEAAQTY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALHALVLQMKSM--------NVGDPRTFPFIEPPPTA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLRDQGALDSSETLTPIGALL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLSVAAALSVQSPFTRSAQ--SSLEGVAARRPLESDHGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

LS
IFN--AWVQVKSERSRNS---RKWCRRHGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1066)

RQ-FKELLQDHG
LLAEAQ--APEDSYHWLQQRRERRALHHLKRQDGGA--MGRRKGLALPGGRVEDLSDE--
D--AAGISPGVEADVTMRDVKFKLRHNLAQLQAAASATQD-LTREQMALLKLVLGRGLYP
QLAVPDPLNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFTNSPEVLFTQEPE-
---AGGGEGDQXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXX-XXXX
XXXX-XXXXXXXXXXXXXXXXX-XXXXXXXXXXXX--XXXXXXXX----------X-XXX
XXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPYSLRRLTGLEVQ
NLYVGPQTVPA-APSLPGLFGSSTLAPHPTKGGYAVTEFLTYNCLTSDTDLYSDCLRSFW
TCPQCGLHAPLTPLERIAHEHACPQAPQAGTPGA----EEAAPEPTPK-PSALQRPYHCE
VCQKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MAPPRTREGRGH-------RDHRWPPSEEEAWERWDWDCPETRGLFEDAFFGDED
YIRQGSEECQKFWAFFERLQRFQNLKTSKK--EE-K----DPRPPQHCI-PALADLPRTY
DPRYRINLSVLG--P-DA-WS------TRRLGSRLPPERVSEFRQALLHYLDFSQKQAFG
RLAKLQRERAALPIAQYRNRILQMLKQHQVV-VVAGDTGCGKSTQVPQYLLAGGFSHVAC
TQPRRIACVSLAKRVGFESLSQYGSQVGYQIRFESTRSVATKIVFLTVGLLLRQIQHEPS
LPQYNVLIVDEVHERQLHSDFLLGVL-RRLLPTRPDLKVVLMSATINIELFSSYFGNAPV
VQVP-GRLFPITVIYQPQEA-E--QTASKTEKLDPRPFLRVLEAIDSKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYAIHTQRWVVLPLHSTLSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVLDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 732)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAI

PF04408 // ENSGT00910000144017_3_Domain_2 (732, 836)

LYLRDQGALDASEALTPIGCLL-------------AQLPVDVVI----G
K-MLILGSTFSLVEPVLTIAAALSVQSPFTRSAQ--SSLECAAARRPLESDQGDP

ENSGT00910000144017_3_Linker_2_3 (836, 889)

FTLFN
VFN--AWVQVKAEHSRIS---RKWCRRRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1137)

RQ-FKELLEDHG
LQAGAQVVRPRDSYSRLQQRRERRVLHQLKRQHE-EGKGRRRKVLRLQEEADDGSSDE-D
R--AGPAAQGASDSVDIQDVKFKLRHNLEQLQAAASSAQE-LSREQLALLKLVLARGLYP
QLAVPDPLNSG--------RKDSDQIFHTQAKQGAV---LHPTCIFTGSPEVLHTWEP--
--EATGGGGSRGDKDKMSSKHQLLTFVSLLE-TNKLYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLVDSEG-AVRLLAAALRLR--ARWESALDQQ--------LSHQA
WQRQRL------------EEEDEAALISHTEVAALSRELLQFVATKVPYSLRRLTGLEAQ
NLYVGPQTILA-TPSLPGLFGSSTLSPHPTKGGYSVTSFLTYNCLSSDTDLYSDCLRTFW
TCPHCGLHLPLTPLERMAHESVCTTGP-DGAPGA----EEAAPEHPQK-PSALQRPYHCD
TCQKDFLFTPTEALRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDC-------RDHPRAPREEEALEKWDWSCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DSGPPKHSI-PALADLPRTY
DPRYRINLSVLG--P-DT-RG------SRELGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQMLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAHLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGVEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGAQAMQAGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGASDGVDIQDVKFKLRHDLAQLQASASSARD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLQAREP--
--EAGSCDGSRDD-QKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCTRLVADGWLELQLADSES-AIRLLAASLRLR--ARWESALDRQ--------LAHQA
RQRL------------EEE---EEEPVSPKEVAALSKELLQFTASKLPYSLRRLTGLEAQ
NLYVGPQTIPV-TPHLPGIFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGKDR-------RDHHRAPSEEEALEKWNWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPRYRINLSVLG--P-AT-RG------SQGLGRHLPAERVAEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-QRLLPTRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGAQAAPVGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGASDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGIPEVLHAQEL--
--EASNCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AIRLLAASLRLR--ARWESALDRQ--------LAHQA
QRQL------------EEE--EQDTPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NMYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTNDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
----MPPPPGTREGRDHLDR---DRRHHRAPREEEAAEKWDWNCPETRRLLEDAFFRDED
YIRRGSEECQKFWAFFERLQRFQHLKAPRK--EE-K----GAGHPKRGIPPALADLPRTY
DPRYRINLSILLRPA-DT-RS------CQGSGRCLPPERASEFRRALLHYLDFAQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKDHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPT
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPRRPDLKVILMSATINISLFSSYFSQAPV
VQVP-GRLFHITVVYQPQEA-E--QTASKSERLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLDAAQAYASLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVC
YRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-GPSLTALPRAQTSRLGTDS-----------------------HPALQGGTGA------
---------------------PTFCTEENTEP-MPVQSPLAVPTHLCPSC-PQELLEDHG
LLSGAQVVAPGDSYSRLQQRRERRALHQLKRQHE-EGGGRRRKVLRLQE--DGCSSDEDH
E---G-SASQRADSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLTL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1138)

LKLVLGRGLYP
QLAVPDAFNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFANSPEVLHTQGQEA
---SGREE-SQDDKDQMSCKHQLLAFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSIDT
NGDCSRLVADGWLELQLADSES-AVRLLATSLRLR--AHWESTLDRQ--------LAHQA
QRQ-RL----------EQEEEADSPAVSPREVAALSTELLQFMAAKVPYSLRRLTGLEAQ
NLYVGPQTITT-APSLPGLFGNSTLSPHPTKGGYAVSDFLTYNCLTSDTDLYSDCLRSFW
TCPHCGLHMPFTPLERIAHENTCPEAPRDDP-GS----EEAAPAPPQK-TSALQRPYHCP
VCGEDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRD-----HRDRDHHRAPRKEEAPEKWDWNCPETRCLLEDVFFRDED
YIRRGSEECQKFWAFFERLQKYQHLKTSQKE-KD-P-------GPKHGI-AALADLPCTY
DPRYRINLSILG--P-DT-RG------RHGPGKGLPPERVSEFRRALLHYLDFQQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQCEPR
LPQYQVLIVDEVHERHLHNDFLLGVL-QRLLPQRPDLKVILMSATINISLFSSYFSHAPV
VQVP-GRLFPITVVYQPQEA-E--QSASKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLDAAQAYATLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPAA
SVE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLQDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MMILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SNLDCATARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSGNS---RKWCRRRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLEDHG
LLRGAQVVAPRDSYSRLQQRRERQTLHQLKRQHE-EGGGRRRKVLRLQE--DGCSSD-ED
H---EGSASQRADSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLALLKLVLGRGLYP
QLAVPDAFNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFANSPEVLHTQGPEA
---SGREG-SQDGKDQMSCKHQLLAFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSIDT
NGDCSRLVADGWLELQLADSES-AVRLLATSLRLR--AHWESALDRQ--------LAQQA
Q-RRKL----------EQEEDPESPAVSPQEVAALSRELLQFMAAKVPYRLRRLTGLEAQ
NLYVGPQTITT-APSLPGLFGNSILSPHPTKGGYAVSDYLTYNCLTSDTDLYSDCLRSFW
TCPHCGLHMPFTPLERIAHENTCPEAPSDGP-GK----SVCVCVCV------CVCVYECE
SYVRVCLYVCVSL-----------------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MSPPRTREGRDC-------RDHPRASREEEGLEKWDWSCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRR--EE-K----ASGPPKHSI-PALADLPRTY
DARYRINLSVLG--P-GT-RG------SRELGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGIL-RRLLPKRPDLKVVLMSATINISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAHLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SMGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSLFSLAEPVLTIAAALSIQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAEAQAVQAGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGAGDGVDIQDVKFKLRHDLAQLQAAASSTRD-LSCEQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAREP--
--EAGSCDGSRDD-QKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCTRLVADGWLELQLVDGES-AIQLLAASLRLR--ARWEGALDRQ--------LAHQA
RQRL------------EEEEEEEEEPVSPKEVAALSKELLQFTASKLPYSLRRLTGLEAQ
NLYVGPQTIPV-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPSGA----EEDAPETLQK-TSVLQSPYHCE
ACEKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MSSSKRTEGRD--------------CQRPESSGRWDWGCPETRSRLEEVFFGDKD
IIRRGSEDCRKFWAFFERLQTFQKPKLPRDA-------------QPRPRCPALADLPATY
DPRYRINGL--------A-ER------SRGAHNQLPRDRLAEFRRAVLHYLDFGQKQSFG
KLTKLQRERAALPMAQYQRHLLQALKEHQVV-IVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSQVGYQIRFESTRSPATKIVFLTEGLLLRQIQREPA
LPQYQVLIVDEVHERHLHSDFLLGVL-RRLLPARPDLKLILMSATINISLFSSYFSHAPV
VQVP-GRLFPITVIYQPIPKEE--VPTSKAEKLDPRPFLRVLQAIDHKYPPEERGDLLVF
LSGMAEISTVLEAFQPY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ATHTKRWVVLPLHSALSIADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGVRFVLDSGKVKEMSFDPKAKLQRLQEFWISRASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 782)

GPGVC
YRLYAESDYDDFAPYPVPEIQRVALDALVLQXXXXXXXXXXXXXXXXXXXXXXXXX----
---------XXXXX----XXXXXXX-------------XXXXXXXXXXXXXXXXXXXXXX
K

PF04408 // ENSGT00910000144017_3_Domain_2 (782, 839)

-ILILGCLFDLVEPVLTMAAALSVQSPFVRSAQ--SNLECGTARKPLESDHGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

LN
AFN--AWVQVKSDRSANS---RKWCRRRGLEE-HRMY-----EIANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1157)

QQ-FQGLLKDHG
LLAEAK-PSPGDSYSRQQRHRRRQELYQLKRQHE-EGEGRKRKVLRLEALEGGSSSEEDR
G--VRSQARDGARRVDIQDVKFKLRHDVDQLHAAASSAQD-LSQDQLALLKLMLGRGLYP
QLAAPDQFNSC--------RKDSDQFFHTQSKQGAV---LHPTCVFASNPDLLQGSQLRP
DKSRXXXXXXXXXXXX-------XXXX-XXX-XXXXXXXXXXXXXXXXXTLLLFSRSLDT
SGDCSRLVADGWLQLQLEGSEG-AMQMLSAALRLR--ARWEEALDRQ--------LARQA
QPRGE--------------DGAAMTPVRRKAAAALGWDLLDFMRSKVSYSIHRLTALEAQ
NLYVGPQTITA-APQLPGLFS--------------------------DADLYSDCLRTFW
SCPHCGLYMPFTPLERMSHENSCQEAPDEDAHEA----EEEADS--GRQASTLRRAYRCE
VCQKDLLLTPTEILRHRRLHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRAY
DPRYRINLSVLG--P-DT-RG------SQGLGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_4 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LMTGAQATQVADSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSEE-D
R--AGPDPPGAGDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_4 (1010, 1363)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEP--
--EASSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQA-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------EEAAPETLQK-TSVLQRPYHCE
ACGRDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MSPPRTRESRDH-------QDHRQAPREEEALEKWDWHCPETRRLLEDAFFREEN
CIRQGSEECQKFWTFFERLQKFQNLKTSRK--EE-K----ESGHPKHSV-PALADLPHTY
DPRYRINLSVLG--P-DM-RD------SRGPGRHLPPERVSEFRRALLHYLDFGQKQAFG
RLARLQRERAALPIAQYGSR

PF00270 // ENSGT00910000144017_3_Domain_0 (321, 467)

ILKTLREHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPN
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NICLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PATSKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------NVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SSPECVAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--SWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1135)

RQ-FKELLEDHG
LLAGAQATKAEDSYSRLQQRRERRALYQLKRQHE-EGEGRRRKVLRLQEEQAGCSSDE-D
G--AGPASRSSADSVDIQDVKFKLRHNLEQLQEAASSAQD-LTRDQMALLRLVLGRGLYP
QLAIPDAFNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFSSSPEVLHTREP--
--EARGCEGSREDKDKMSSKHQLLTFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ERWESALDRQ--------LAHQA
QRQRKL----------EEEEENETLPISPKEVAALSRDLLQFMASKVPYSLRRLTGLETQ
NLYVGPQTITA-APNLPGLFGSSTLSPHPTKGGYTVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHMPFTPLERITHENTCPKALQDGPPGT----EEDASEPLQK-ASALQRPYHCE
HCQKDFLFTPTEVLRHRKQHL---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------VGYQIRFESTRSAATKIVFLTVGLLLRHLQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPERPDLKVILMSATINISLFSSYFGGAPV
VQVP-GRLFPITVVYQPQEV-E--PATSKSEKLDPRPYLRVLEAIDNKYPPEERGDLLVF
LSGMAEISTVLEAAQTY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKVQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
FRLYAESDYEAFAPYAVPEIRRVALDAMVLQMKSM--------NVGDPRTFPFIEPPPPA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLQDQGALDSSEALIPIGSLL-------------TQLPVDVVI----G
K-MLILGCTFHLAEPVLTIAAALSVQSPFTRSAQ--SNPECVAARRPLESDQGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

FN
VFN--TWVQVKSERSGNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLEEHG
LLAGAQAREPGDSSRRLQQRRERQALHRLKRQHE-AGGGRRRKVLRLQEGQVGCSSDE-D
E--GGTASRGAGDNVDIQDVKFKLRHNLQLHA---TSSAH-ALTRQMVLLKLLMGRGLYP
QLAVPDPFNSG--------RKDSVQIFHTQAKQGTV---LHPTCVFANSPEVLHAQEQEH
EREARAGEGSRDDRDKMSSRHQLLTFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NADCSRLVADGWLELQLVDSEN-AIQLLAASLRLR--AHWESALDRQ--------LAHQA
RRRLPE---------EEEEEEEEDGRISHKEVVALSRGLLQFMASKVPYRLRRLTGLETQ
NLYVGPQTITA-APSLPGLFGSSALSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHLPLTPLERMAHENTCPQAPRDGPPGA----EEAVPEPQQK-ASALQRPYHCE
ACQQDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MAPPRTREGRGH-------RDHRWPPSEEEAWERWDWDCPETRGLFEDAFFGDED
YIRQGSEECQKFWAFFERLQRFQNLKTSKK--EE-K----DPRPPQHCI-PALADLPRTY
DPRYRINLSVLG--P-DA-WS------TRRLGSRLPPERVSEFRQALLHYLDFSQKQAFG
RLAKLQRERAALPIAQYRNRI

PF00270 // ENSGT00910000144017_3_Domain_0 (322, 467)

LQMLKQHQVV-VVAGDTGCGKSTQVPQYLLAGGFSHVAC
TQPRRIACVSLAKRVGFESLSQYGSQVGYQIRFESTRSVATKIVFLTVGLLLRQIQHEPS
LPQYNVLIVDEVHERQLHSDFLLGVL-RRLLPTRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 532)

NIELFSSYFGNAPV
VQVP-GRLFPITVIYQPQEA-E--QTASKTEKLDPRPFLRVLEAIDSKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYAIHTQRWVVLPLHSTLSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVLDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 732)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAI

PF04408 // ENSGT00910000144017_3_Domain_2 (732, 836)

LYLRDQGALDASEALTPIGCLL-------------AQLPVDVVI----G
K-MLILGSTFSLVEPVLTIAAALSVQSPFTRSAQ--SSLECAAARRPLESDQGDP

ENSGT00910000144017_3_Linker_2_3 (836, 889)

FTLFN
VFN--AWVQVKAEHSRIS---RKWCRRRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1137)

RQ-FKELLEDHG
LQAGAQVVRPRDSYSRLQQRRERRALHQLKRQHE-EGKGRRRKVLRLQEEADDGSSDE-D
R--AGPAAQGASDSVDIQDVKFKLRHNLEQLQAAASSAQE-LSREQLALLKLVLARGLYP
QLAVPDPLNSG--------RKDSDQIFHTQAKQGAV---LHPTCIFTGSPEVLHTWEP--
--EATGGGGSRGDKDKMSSKHQLLTFVSLLE-TNKLYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLVDSEG-AVRLLAAALRLR--ARWESALDQQ--------LSHQA
WQRQRL------------EEEDEAALISHTEVAALSRELLQFVATKVPYSLRRLTGLEAQ
NLYVGPQTILA-TPSLPGLFGSSTLSPHPTKGGYSVTSFLTYNCLSSDTDLYSDCLRTFW
TCPHCGLHLPLTPLERMAHESVCTTGP-DGAPGA----EEAAPEHPQK-PSALQRPYHCD
TCQKDFLFTPTEALRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRIREGKDD-------WDHRQVPSKEEVLKKWDWNCPETRRLLEDAFFREED
YIRRGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGHTKHSI-PALADLPRTY
DPRYRINLSILG--P-DT-RG------SRGLSRCLPPERVSEFRQALLHYLDFVQKQGFG
RVAKLQRERAALPIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPT
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPTRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVIYQPQEA-E--PSTSKSEKLDPRPFLRVLESIDNKYPPEERGDLLVF
LSGMAEISAVLEAAQTY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ASHTQRWVVLPLHSTLSVADQD-VFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLRDQGALDASEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--NSPECAAARRPLESDQGDPFTLFN
IFN--AWVQVKSERSRNS---RKWCRRRGVEE-HRLY-----EMANLRRQ-FKELLVDHG
LLAGAQAAQPGDSYTRLQQRRERRALHQLKRLHE-EGGGRRRKVLRLQEEEPGCSSDE-D
P--ARPASQGA-GDVDIQDVKFKLRHDLQQLQAAASSAQE-LTRDQMALLKLVXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX--------X---X----XXXXXXXXXXXXXXXX
XXXXXXXXXXXXDKDKRSSGHQL--FVSLLE--NKLYLVNCVRIA-LQSLL-LFSRSLDT
NGDCTRLVADGWLELQMADSES-AVRLLGTSLRLR--AHWESALDRQ--------LARHA
RGRLE-------------EEEEEDPPVSPKEVASLSRELLCFMASKVPYSLRRLTGLEAQ
NLYVGQTVTT---PQL-PLFGSSALTS-PTRGXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXV----EEATPELPQK-ATALQRPYHCE
VCQEDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIHQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DAGQPKHSI-PALADLPRAY
DPRYRINLSVLG--P-DT-RG------SQGLGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAVQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LMTGAQATQVADSYSRLQQHRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSEE-D
Q--AGPDPPGAGDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEP--
--EASSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ARWEGALDRQ--------LAHQA
QRRL------------EEE--EQDVPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NLYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGRDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------QDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPCYRINLSVLG--P-DT-RG------SGGLGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKQHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQVRHGQKWDYMLTAAWGPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRNAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LMTGAQATQVADSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGAGDGVDIQDVKFKLRHDLAQLQAAATSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPQVLHAQEP--
--EAGSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NSDCSRLVADGWLELQLTDSES-AVRLLAASLRLR--ACWEGALDRQ--------LAHQA
RRRL------------EEE--EQDVPVSPKEVATLSKELLQFTACKIPYSLRRLTGLEAQ
NLYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREERD-----HRDRHHHRAPREEEAAEKWDWNCPETRRLLEDVFFRDED
YIRRGSEECQKFWAFFERLQRFQHLKAPRK--EE-K----DPGHPKRGI-PALADLPRAY
DARYRINLSILG--P-DP-RS------CQGPGRRLPPERVSEFRRALLHYLDFAQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPT
LPQYQVLIVDEVHERHLHNDFLLGIL-RRLLPGRPDLKVILMSATINISLFSSYFSHAPV
VQVP-GRLFPITVVYQPQEA-E--QTTSKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLDAAQAYASLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 732)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAI

PF04408 // ENSGT00910000144017_3_Domain_2 (732, 842)

LYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SNLDCATARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 889)

FN--AWVQVKSERNKNS---RKWCRRRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLEDHG
LLSGAQAEAPRDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQE--DVGSSD-ED
H---EGPASQRADSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLTLLKLVLGRGLYP
QLAVPDAFNSG--------RKDTDQIFHTQAKQGTV---LHPTCVFANSPEVLHTQGQEA
---SGREG-SQDAKDQMSCRHQLLAFVSLLE-TNKPYLVNCVCIPALQSLL-LFSRSIDT
NGDCSRLVADGWLELQLVDSES-AVRLLATALQLR--ARWESALDRQ--------LAQQA
Q-RQQL----------GQEEEVESPAVSPREMATLSRELLQFMAAKVPYSLRRLTGLEAQ
NLYVGPQTITT-APSLPGLFGNSTLSPHPTKGGYAVSDFLTYNCLTSDTDLYSECLRSFW
TCPHCGLHMPFTPLERIAHENTCPEAPREDP-GS----EEAASAAPQK-ASALQRPYHCQ
LCGEDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTKEGRDH-------RGRLWDPSEEEALEKWDWNCPETRRIFEDAFFRDED
YIRQGSEECQKFWAFFERLQRFQNLKATSK--GE-K----APARPQHSI-PALADLPCTY
DPRYRINLSILG--P-DT-RD------SRGLAR-QPPERVAEFRRALLHYLDFGQKQAFS
RLAKLQRERAALPIAQYGNR

PF00270 // ENSGT00910000144017_3_Domain_0 (321, 467)

VLQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSQVGYQIRFESTRTAATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPQRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 565)

NISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PPASKSEKLDPRPFLRVLEAIDNKYPPEERGDVLVF
LSGMAEISSVLEAAQAYAGRTQRW

PF00271 // ENSGT00910000144017_3_Domain_1 (565, 656)

VVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMGYDPQAKLHRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SMGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLRDQGALDSSESLTPIGSLL-------------AQLPVDVVI----G
K-MLILGCMFHLAEPVLTIAAALSVQSPFTRSAQ--SHPECAAARRPLESDHGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSRNS---RKWCRRRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1135)

RQ-FKELLEDHG
LLARAQAATPGDSSRRLQERRERRELYRLKRQHE-EGGGRRRKVLRLQEGVDGGSSDE-D
R--------GAGDGVDIQDVKFQLRHSLDQLQAATSSAQD-LTRDQMALLKLVLGRGLYP
QLAVPDPFNSS--------RKDSDQIFHTQSKQGTV---LHPTCIFANSPEVLHTQEQ--
--AARGGEAGRDDKDKVSSKHQLLIFVSLLE-TNKPYLVNCVRVPALQSLL-LFSRSLDT
NGDCSRVVADGWLELQLADSES-ALRLLAASVRLR--TQWESILDRQ--------LAHQA
QRQRPE---------VDEGED-AAAPGDRREVADLSRDLLRFVASEVPYSLRRLTGLEVQ
NLYVGPQTITA-VPSLPGLFGSSTLSPHPTKGGYAVADFLTYNCLEVSMDPTSAHHPT--
---------------------PDPKQRESRPPRD--------------------------
------------------------------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREDRGH-------RDRHWAPREEEAPEKWDWNCPETRHLFEDAFFRDED
YIRQGSEECQKFWTFFERLQRFQHLKATRK--ED-R----DPEHPKHSI-LALADLPGAY
DPRYRINLSVLG--P-DL-RG------SRRLGRHLPPERVSEFRQALLHYLDFVQKQAFG
RLAKLQRERAALPIAQYGHRILKTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFGSAPV
VQVP-GRLFPITVVYQPIEA-E--PSVSKSEKLDPRPFLRVLEAIDSKYPPEERGDLLVF
LSGMAEISAVLEAAQTY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
FRLYAESDYDAFAPYAVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFHLAEPVLTIAAALSVQSPFTRSAQ--NNPEGAAARRPLESDLGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

FN
VFN--TWVQVKSERSRNS---RKWCRHRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLEDHG
LLAGAQAAKPGDSYSRLQQRRERRELYQLKRQHE-EGGGRRRKVLRLQEEEDGCSSDE-E
R---GQASRAASDHVDIQDVKFKLRHNLEQLQAAASSAQA-LTRDQMALLKLVLARGLYP
QLAVPDPFNGG--------RKDSDQIFHTQAKQGTV---LHPTCVFASSPEVLHTQEP--
--EARGGEGSRDDKDKMSSKHQLLTFVSLLE-TNKPYLVNCVRVPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADTES-AVRLLAASLRLR--ARWESALDRQ--------LAHQA
RRGQPA---------KEEEEEEEEAPVNRQEVVALSRELLQFTAAKVPYTLRRLTGLEAQ
NLYVGPQTITT-APSLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHMPLTPLERIAHENTCPEAPPA--AGA----EEAAPEPQQK-TSALQRPYHCE
ACQKDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MSSSKRTEGKG--------------YREPKSSRQWDWGCPETRSQLEEIFFGDQD
VIRRGSEDCRKFWAFFERLQTFQRSKAGLEAKRP-T----EAQAPPRPRGTALADLPATY
DPRYRINLALLSGKGEPV-SE------LRGSRSQLPHDRLAEFRRAVLHYLDFGQKQAFG
KLAKLQRERAALPMARYGRHLL

PF00270 // ENSGT00910000144017_3_Domain_0 (323, 467)

QALQEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSQVGYQIRFESTRSPATKIVFLTEGLLLRQIQREPG
LPQYQVLIVDEVHERHLHSDFLLGVL-RRLLPARPDLKLILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NISLFSSYFGHAPV
VQVP-GRLFPITVIYQPVPKEE--APTSKSEKLDPRPFLRVLQAIDHKYPPEERGDLLVF
LSGMAEISAVLEAFQPYAAHTKRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSALSITDQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGVRFVLDSGKVKEMSFDPKAKLQRLQEFWISRASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDDFAPYPVPEIQRVALDALVLQMKSM--------GLGDPRNFPFIEPPPAA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 839)

AIVYLRDQGALDASENLTPIGTLL-------------SELPVDVVI----G
K-ILILGCLFDLVEPVLTMAAALSVQSPFVRSAQ--SNLDCGTARKPLESDHGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 891)

LN
AFN--AWVQVKSDRSANS---RKWCRRRGLEE-HRMY-----EIANLRRQ

PF07717 // ENSGT00910000144017_3_Domain_3 (891, 1135)

-FKGLLQDHG
LLAEAR-PAPADSYSRQQQHRQRRELYQLKREHE-ESEGRKRKVLRLEALEGGSSSDE-D
A--EASRAREGAHAVDIQDVKFKLRHDMGQLQAAASSAQD-LSRDQLALLKLVLGRGLYP
QLATPDQFNGC--------RKDSDQFFHTQSKQGAV---LHPTSVFASNPDLLQGGQTE-
-----AREKGRDSKDGLSSRHQLLAFVSLLE-TNKPYLVSCVRLPALQAVL-LFSRSLDT
NGDCSRLVADGWLEFRLESSER-ATQLLSTALRLR--ARWEEALDRQ--------LARQA
QPRSEE-------------RAAMALKAERKVAAALGRDLLDFMRSKVSYSTHRLTALEAQ
NLYVGPQTVPA-APQLSAVFGETAMSPHDTKGGYAVTSFLTYNCLMSDTDLYSDCLRTFW
SCPHCSLYMPFTPMERMCHENTCQAAPDQAAPGA----SDEEAESSRQ-ASALQRTYHCE
LCQKDLLLTPTEILRHRKQHL---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDH-------RDYRRAPTGEEAWEKWDWNCPETRRLLEDSFFRDED
YIRQGSEDCQKFWAFFERLQRFQSAKTSRK--EE-K----DAGCPKHGT-SALADLPHTY
DPRYRINLSIIG--P-DA-RG------SRGPGRRLPPERVSEFRQALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHNDFLLGIL-RRLLPRRPDLKVILMSATINISLFSSYFGSAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDAKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFRLAEPVLTIAAALSVQSPFTRSAQ--SSPDCATARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRDS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAEARAAGPGDSHSRLQQRRERRALYQLKRQHE-QGGGRGRKVLRLREEQDGCSSDE-D
R--AGAL--RAGDSVDIQDVKFKLRHNLEQLQAAASAAQD-LSREQMAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1128)

LKLVLGRGLYP
QLAIPDAFNSG--------RKDSDQIFHTRAKQGAV---LHPTCVFAGSPEVLHAREQ--
--EVEGCDGNRGDKDRMSSRHQLLAFVSLLE-TNKPYLVNCVRVPALQXXX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX--XXXXXXXXXX--------XXXRQ
AQRP------------EEEEDEEAAPVSPREVAALSRELLQLMASKVPYSLRRLTGLEAQ
NLYVGPQTVTA-APSLPGLFGSATLTPHPTKGGYAVTDFLTYNCLTSDADLYSDCLRTFW
TCPRCGLHAPLTPVERISHENTCAPDPQDAPPGA----EEATPEPLQK-ASALQRPYHCE
ACQKDFLFTPTEVLRHRKLHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MAPPRTREGRGH-------QDHHRAPREEETLEKWDWDCPETRRLLEDAFFRDED
YIRQGSEDCRKFWAFFERLQRFQTLKTSRK--EE-K----DPGHPKHCI-PALADLPRTY
DARYRINLSVLG--P-DT-RD------TWGPGSRLPPKQVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNCILQTLKQHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYKVLIVDEVHERQLHSDFLLGVL-QRLLPTRPDLKVVLMSATINIALFSSYFGSAPV
VQVP-GRLFPITVIYQPQEA-E--QTASKSEKLDPRPFLRVLEAIDNKYP

PF00271 // ENSGT00910000144017_3_Domain_1 (531, 656)

AEERGDLLVF
LSGMAEIGAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIEGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDAFAPYAVPEIRRVALDALVLQMKSM--------CVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 842)

AIQYLRDQGALDTSEALTPIGCLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAH--SSLECAAARRPLESDQGDPFTLFN
VFN--AWVQVKAERSQNS---RKWCRRRGVEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGAQSTTPGDSSSRLQQRRERRALQQLKRQHE-EGEGRRRKVLRLQEEAEVGSSDE-D
H--AGPAARRADDSVDIQDVKFKLRHNLEQLQAAASSAQA-LTREQLLLLKLVLARGLYP
QLAVPDPFNSG--------RKDSDQIFHTQAKQGAV---LHPTSVFANSPEVLHTQEP--
--PATGGGGSRASARW---------------------CLPAVLSTPYPSLL-LFSRSLDT
NGDCSRLVADGWLELQLVDREG-AVRLLALALRLR--ARWESTLDRQ--------LSQQA
WQRQR----------LKDEDEESVAPVSCSEVAALSRELLQFMATKVPYSLRRLTGLETH
NLYVGPQTITA-TPSLPGLFGSSTLSPHPTKGGYSVTDFLTYNCLSSDTDLYSDCLRTFW
TCPRCDLHLPFTPLERMAHENACAAGL-EGDPGT----EEASPEHPQK-PSALQRPYHCD
TCQKDFLFTPTEALRHRRQHL---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHRAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLRTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPRYRINLSVLG--P-DT-RG------SQGLSRHLPAERVAEFRRALLHYLDFGQKQAFG
RLAKLQHERAALPIAQYGNRILQTLEEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPTRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEV-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEATQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 782)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQSM----------SVGDPRTFPFIEPPPPA
ILE-----TAILYLRDQGALDSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----X
H

PF04408 // ENSGT00910000144017_3_Domain_2 (782, 867)

-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLRV----------
-------TRVKSERSRNS---RKWCR

ENSGT00910000144017_3_Linker_2_3 (867, 1010)

RRGIEE-HRLY-----EMANLRRQ-FKELLEDHR
LLAGAQAAQVGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPALPGASDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLVL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPQVLHAQEL--
--EASSCDGSRDDKDKMISKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADSWLELQLADSES-AIRLLAASLQLR--ARWESALDRQ--------LAHQA
QRRL------------EEE--EQDAPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NMYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQGGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRGP-------WDRPRAPSPEAAPEKWDWNRPETRRLFEDAFFGDED
YIQQGSEECQKFWTFFERLQRFQNLKTTRK--EE-K----DARQPKHSH-PALADLPRTY
DPQDRINLSFIS--P-DA-RD------SRGPGRRLPPERLSEFRRALLHYLDFCQKQAFG
RLAKLQRERAALPIAQYGHRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGCSHVAC
TQPRRIACVSLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQMQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPQRPDLKVVLMSATINISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PTASKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEPAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPT
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 834)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFHLAEPVLTIAAALSVQTPFTRSAQ--SNPECAAARRPLESDQG

ENSGT00910000144017_3_Linker_2_3 (834, 1010)

DPFTLFN
VFN--TWVQVKSERGRNS---RKWCRHRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGARAPQPGDSYSRLQQRWERQALYQLKRRHE-EGAGRKRKVLRVQDNQDGWSSDE-D
R--GGSASQGASDSVDIQDVKFKLRHNLEQLQAAASSAQA-LTRDQMAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDPFNSG--------RKDSDQIFHTQTKQGVV---LHPTCVFANSPEVLHTQEQ--
--AAKGSDGSRDDRDKMSSKHQLVTFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADTES-AVRLLAASLRLR--AHWESALDRQ--------LAHQA
RRRLED--------EGEE--EEEEAPVNHKEVAALSRELLQFTASKVSYSLRRLTGLEAQ
NLYVGPQTITA-APSLPGLFGNSVPSPHPTKGGYAVTDFLTYNCLTSDADLYSDCLRTFW
TCPHCGLHMPLTPLERIAHENTCPEAPQDGPPGA----EEAAPEPPQK-ASALQKPYHCE
ACQKDFLFTPTEILRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------QDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPRYRINLSVLG--P-DT-RG------SQGLGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDMAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LMTGAQATQVADSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGAGDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSCEQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEP--
--EAGSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NSDCSRLVADGWLELQLTDSES-AVRLLAASLRLR--ARWEGALDRQ--------LAHQA
QRRL------------EEE--EQDAPVSPKEVATLSKELLQFMASKIPYSLRRLTGLEAQ
NLYVGPQTIPA-TPHLPGLFGSSTQSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFVFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRG-----HRDRDHHRAPREEEAPEKWDWNCPETRCLLEDVFFRDED
YIRRGSEECQKFWAFFERLQRFQHLKTSQK--KE-K----DPGMPKHGI-AALADLPLTY
DPRYRINLSILS--P-DT-RG------RHGPGRGLPPERVSEFRRALLHYLDFQQKQAFG
RLVKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-QRLLPQRPDLKVILMSATINISLFSSYFSHAPV
VQVP-GRLFPITVVYQPQEA-D--QTASKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEITTVLDAAQAYASLTQRWVVLPLHSALSVSDQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SVE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 835)

ILYLQEQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SNLDCATARRPLESDQGD

ENSGT00910000144017_3_Linker_2_3 (835, 1010)

PFTLFN
VFN--AWVQVKSERSGNS---RKWCRRRGVEE-HRLY-----EMANLRRQ-FKELLEDHG
LLSGAQVVAPGDSYSRLQQRRERRALHQLKRQHE-EGGGRRRKVLRLQE--DGCSSDEED
R---EGSTSQRADSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1138)

LKLVLGRGLYP
QLAVPDAFNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFANSPEVLHTQGQEA
---SGQEG-SQDGRDQMSCKHQLLAFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSIDT
NGDCSRLVADGWLELQLADSES-AVRLLATSLRLR--VHWESALDRQ--------LARQA
Q-RRKL----------EQEEDMGSPAVSPQEVAALSRELLQFMVAKVPYRLRRLTGLEAQ
NLYVGPQTITT-APSLPGLFGNSTLSPHPTKGGYAVSDYLTYNCLTSDTDLYSDCLRSFW
TCPHCGLHMPFTPLERIAHENTCPEAPGDDP-GS----EEAAPAPPQK-TSALQRPYHCQ
VCGQDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MAPPGTREGKGH-------RDVRRARGEDDAPERWDWDCPETRRRFEDAFFGDED
DIRRGSEECQKFWAFFERLQRFQNLKTSRK--EE-K----EPERPQHCI-PALADLPPAY
DPRXXXXXXXXXXXX-XX-XX------XXXXXXXXPRERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYANPILQ

PF00270 // ENSGT00910000144017_3_Domain_0 (324, 467)

MLKQHQVV-LVAGDTGCGKSTQVPQYLLAAGFRHVAC
TQPRRIACVSLAKRVGFESLSQYGSQVGYQIRFESSCSAATRIVFLTVGLLLRQIQREPS
LPQYSVLIVDEVHERQLHNDFLLGVL-RRLLPTRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 532)

NIALFSSYFGHAPV
LQVP-GRLFPITVIYQPQEA-E--QTASKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 625)

EERGDLLVF
LSGMAEISAVLEAAQPYASHTQRWVVLPLHSALSMAEQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEM

ENSGT00910000144017_3_Linker_1_2 (625, 732)

SYDPQAKLQRLQEFWISRASAEQR------------
---------------------KVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAI

PF04408 // ENSGT00910000144017_3_Domain_2 (732, 838)

LYLRDQGALDASETLTPIGCLL-------------AQLPVDVVI----G
K-MLILGSTFGLVEPVLTIAAALSVQSPFPRSAQ--SSPECTAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 1018)

LFN
VFN--AWVQVKAERSRNS---RRWCRRRGVEE-HRLY-----EMANLRRQ-FKVTRSALG
FFLR--------------------------------------------------------
-----------------------------------------------------MGSL

PF07717 // ENSGT00910000144017_3_Domain_3 (1018, 1137)

FWP
LLPSP-------------------------------------------------------
---RVAMLDLADDKDKMSSKHQLLTFVSLLE-TNKLYLVNCVRVPALQSLL-LFSQSLDT
NGDCSRLVADGWLELQLVDSEGAARQQ---------------------------------
---------------LEEEDEEEAAPLSRTEVATLSQELLQFMATKVPYSLRRLTGLEAQ
NLYVGPQTITA-MPSLPGLFGSSALSPHPTKGGYSVTDFLTYNCLSSDTDLYGGCLRTFW
TCPHCGLHLPLTPLERMAHESTCAEGP-DGAPGA----EEAASEQPQK-ASALRRPYRCD
SCQKDFLFTPIEALRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHRAPSEEEALEKWNWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPRYRINLSVLG--P-AT-RG------SQGLGRHLPAERVAEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-QRLLPTRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 770)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQKEVL--------------AFPQLRPLPPL
SSA---------------------QLGPRGASA------APVLAPRSLN

PF04408 // ENSGT00910000144017_3_Domain_2 (770, 842)

PVSAAA----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRLLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGAQAAPVGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGASDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEL--
--EASNCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AIRLLAASLRLR--ARWESALDRQ--------LAHQA
QRQL------------EEE--EQDTPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NMYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTNDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRNQ-------RDHHQAPNEDEILERWDWNCPETRRLLEDAFFREEG
CIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGHRKDSV-PALADLPRTY
DPRYRINLSVLG--P-DV-RG------SRGPGRGLPPERVSEFRRALLHYLDFGQKQAFG
RLARLQRERAALPIAQYGTRILKTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFGNAPV
VQVP-GRLFPITVVYQPHEA-E--PTASKSEKLDPRPFLRVLEAIDNKYP

PF00271 // ENSGT00910000144017_3_Domain_1 (531, 656)

AEERGDLLVF
LSGMAEIGAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 733)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPAA
SLE-----TAIF

PF04408 // ENSGT00910000144017_3_Domain_2 (733, 849)

YLQDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFNLEEPVLTIAAALSVQSPFIRSAQ--GSPECVAARRPLESDQGDPFTLFN
VFN--AWV

ENSGT00910000144017_3_Linker_2_3 (849, 1010)

QVKSERSRNS---RKWCRRRGVEE-HRLY-----EMANLRRQ-FKDLLADHG
LLARAQAREAEDSHSRLQQRRERRTLFQLKRRHE-EGGARRRKVLRLQEEQAGCSSDE-D
R--AGPAPQGAADSVDIQDVKFKLRHNLEQLQAAASSAQD-LTCDQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDEFNSG--------RKDSDQIFHTRAKQGTV---LHPTCVFASSPEVLHARER--
--EARGREGSREDRDKMSSRHQLLAFVSLLE-TNKPYLVNCVRVPALQSLL-LFSRSLDT
SGDCSRLVADGWLELQLADAES-AVRLLAAALRLR--ARWESALDRQ--------LARQA
GPR-------------PQEEEEEALPLSPKEVAALSRDLLQFMASKVPYSLRRLTGLETQ
NLYVGPQTITA-APSLPGLFGSSPLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCDLHMPFTPLERIAHEHACPQAPQGGPPGS----EDAAPEPLQK-ASALQRAYRCE
HCQKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
------------ESRDRGRENRDRGRESRGYRSQPDAGSWDWDCPDTRRRLEEVFFREQD
SVRAGSEDCRQFWAFFERLQRFQAQRRERTGEEEGEGEQPAPGQ-ADARHPALADLPRTY
DPRYRINLALLSGGEVEDRGD------RRTAAAAIPRERLAEFRLAVLQYLDFMQKQSLA
KLAKLQKERAALPIARLAPRLLSV

PF00270 // ENSGT00910000144017_3_Domain_0 (325, 467)

LRENQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVAFESLNQYGSQVGYQIRFESTRSAATKVVFLTEGLLLRQIQRQPT
LPQYQVLIVDEAHERHLHSDFLLGVL-RQLLPARPDLKVVLMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NIALFSAYFGQAPV
VQVP-GRLFPISVRKWRA-----------------------------------SGVGVVX
LSGMAEISAVPEAAQTYATHTQRWI

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 659)

VLPLHSTLSVPDQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGVRFVLDSGKVKEMSFDPKAKLQRLQEFWISRASAEQR----------

ENSGT00910000144017_3_Linker_1_2 (659, 730)

IC
YRLYAESDYDAFAPYPVPEIQRVALDALVLQMKSM--------GLGDPRTFPFIEPPPSS
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 839)

AVLYLRDQGALDAAEDLTPIGNLL-------------AQLPVDVVI----G
K-MLILGSLFQLVEPVLTVAAALSVQSPFLRSGH--SNPDCGTARKPLESSHGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 994)

LN
AFN--AWVQVSGGRFGGTTYSACWVTHLLCRGT-RER-----APSALRVTGKGPLVIDSG
GLDGVL-GAPGSGPARPCKRRV----------------SRKRKILGEGTLPFPGPLVT-S
P--PPGSSSSGPTSLPLADVKFKLRHSVDELQA

PF07717 // ENSGT00910000144017_3_Domain_3 (994, 1070)

AASAGRD-LSRDELALLKLVLARGLYP
QLAAADHFNSC--------RKDSDQIFHTKTKQGTV---LHPTSVFASNPEVLQVSGRDT
DDQK--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDH-------RDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRAY
DPRYRINLSVLG--P-DT-RG------SQGLGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LMTGAQATQVADSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSEE-D
R--AGPDPPGAGDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEP--
--EASSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ARWEGALDRQ--------LAHQA
QRRL------------EEE--EQDVPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NLYVGPQTIPT-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGRDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------FSHVAC
TQPRRIACISLAKRVGFESLSQYGSRVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPP
LP----------------NDFLLGVL-RRLLPRRPDLKVILMSATINISLFSSYFSQAPV
VQVP-GRLFHITVVYQPQEA-E--QTASKSERLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLDAAQAYASLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGGR
VRFRLHISCATVAPVVPEDI------CFSFQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-EVPTGEPWS------------------------------------STSCPGDPWWL--
------ALSVKSERSRNS---RKWCRRRGVEE-HRLY-----EMANLRRQ-FKVRAGPF-
--L----VTRAS--------------------------------------PYHCPSRQ--
---AGPE-----------------------------------------------------
----------------------------------------H----------------PGQ
GGKKSGHFHLSDDKDQMSCKHQLLAFVSLLE-TNKPYLVNCVRIPALQVGLCPD------
---------SGWTVAC----KSCPLPMLAAGMV--CGCGWSLFVALCHGYLLRLAVVSSA
RRSR-------------------------REP--GEGSWRGHKGLKVPYSLRRLTGLEAQ
NLYVGPQTITT-APSLPGLFGNSTLSPHPTKGGYAVSDFLTYNCLTSDTDLYSDCLRSFW
TCPHCGLHMPFTPLERIPP---------LSTTGS----EEAAPAPPQK-TSALQRPYHCP
VCGEDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
----GMPPPRTREGRGP-------RDRPRAPSPEAAPENWDWNRPETRRLFEDAFFGDED
YIQQGSEECQKFWAFFERLQRFQNLKTTRK--EE-K----DARQPKHSH-PALANLPRAY
DPRDRINLSVLG--P-DA-RD------SRGPGRRLPPERVSEFRRALLHYLDFCQKQAFG
RLAKLQRERAALPIAQYGHR

PF00270 // ENSGT00910000144017_3_Domain_0 (321, 467)

ILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGCSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQMQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPQRPDLKVVLMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVF
LSGMAEISAVLEPAQTYASHTQRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 743)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPT
SLE-----TAILYLRDQGALDS

PF04408 // ENSGT00910000144017_3_Domain_2 (743, 838)

SA-------LL-------------AHLPVDVVI----G
K-MLILGSMFHLAEPVLTIAAALSVQTPFTRSAQ--SNPECAAARRA--REQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--TWVQVKSERGRNS---RKWCRHRGIEEHHRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1071)

RQ-FKELLEDHG
LLAGARAPQPGDSQG-----RERQALYQLKRRHE-EGAGRKRKVLRVQDNQDGWSSDE-D
R--GGSASQGASDSVDIQDVKFKLRHNLEQLQAAASSAQA-LTRDQMALLKLVLGRGLYP
QLAVPDPFNSG--------RKDSDQIFHTQTKQGVV---LHPTCVFANSPEVLHTQER--
--ARGGGGGGRGGGGGRGGVGGVRGH----------------------------------
-SDLGVLLAIGGYP------------LT--PPTLH--LPWGT------------------
---------------------------------------------------RRV------
----------T-EPHLAGWPWGGPPPPHMVLAALSLE----SLLSQSDADLYSDCLRTFW
TCPHCGLHMPLTPLERIAHENTCPEAPQDGPPGA----EEAAPEPPQK-ASALQKPYHCE
ACQKDFLFTPTEILRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------QDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPCYRINLSVLG--P-DT-RG------SGGLGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKQHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMADISTVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LMTGAQATQVADSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGAGDGVDIQDVKFKLRHDLAQLQAAATSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPQVLHAQEP--
--EAGSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NSDCSRLVADGWLELQLTDSES-AVRLLAASLRLR--ACWEGALDRQ--------LAHQA
RRRL------------EEE--EQDVPVSPKEVATLSKELLQFTACKIPYSLRRLTGLEAQ
NLYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHRAPSEEEALEKWDWNCPETRRLLEDAFFRKED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPRYRINLSVLG--P-AT-RG------SQGLGRHLPTERVAEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-QRLLPTRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 770)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQVSLP--------------KCWDCRLEPPC
-PA---------------------SICFFRARA------APVLAPRSLN

PF04408 // ENSGT00910000144017_3_Domain_2 (770, 842)

PVSAAA----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGAQAAQVGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGASDGVDIQDVKFKLRHDLAQLQATASSAQN-LSHEQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAREL--
--EASNCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ARWESALDRQ--------LAHQA
QRQL------------E----EQDAPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NMYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDC-------RDHPRAPREKEALEKWDWSCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DSGHPKHSI-PALADLPRTY
DPRYRINLSVLG--P-DT-RG------SRELGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRVLQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAAQTYASHTQRWVVLPLHSALSVAAQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAHLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SMGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGAQAVQAGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGAGDGVDIQDVKFKLRHDLAQLQAAASSARD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHIREP--
--EAGSCDGSRDD-QKMSSKYQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCTRLVADGWLELQLADSES-AVRLLAASLRLR--ARWESALDRQ--------LVHQA
RQRL------------EEEE-EEEEPVSPKEVVVLSKELLQFTASKLPYSLRRLTGLEAQ
NLYVGPQTIPV-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQEGPPGA----EEAAPETLQK-TSVMQRPYHCK
ACGKDFLFTPTEVLRHRKQHVRATPGAPP--A--------SPQSPHPPAQD---------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTKGGGDH-------RGRHWNPSEEEARKNWDWNCPETRRLFEEAFFRDED
YIRQGSEDCQKFWTFFERLQRFQSLKATRK--GE-K----DPSHPKPSV-PALADLPRTY
DPRYRINLSILG--P-DT-RG------SRGLGR-QPPERVSEFRRALLHYLDFGQKQAFA
RLAKLQHERAALPIAQYGNRILQTLKDHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSQVGYQIRFESTRTAATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPERPDLKVILMSATINISLFSSYFGRAPV
VQVP-GRLFPITVVYQPQEA-E--PAASKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVF
LSGMAEISSVLEAAQAYA

PF00271 // ENSGT00910000144017_3_Domain_1 (559, 656)

GRTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMGYDPQAKLHRLQEFWISQASAE----GAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALHALVLQMKSM--------TVGDPRTFPFIEPPPPA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFHLAEPVLTIAAALSVQSPFTRSAQ--SHPECAAARRPLESDQGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

FN
IFN--AWVQVKSERSRNS---RKWCRHRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLEDHG
LLARAQAAMSGDSFRRLQERRERRALYRLKRQHE-ESGGRRRKVLRLREDLDGGSSNE-D
Q--------GAGDGVDIQDVKFQLRHSLDQLQAATGSAQD-LTREQMALLKLVLGRGLYP
QLAVPDPFNSS--------RKDSDQIFHTQSKQGTV---LHPTCIFASSPEVLHTQEP--
--EARGGEVSRDDKDKLSSRHQLLAFVSLLE-TNKPYLVNCVRVPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASVRLR--AHWESILDRQ--------LARQA
QQRRPE---------ADQEEA-AGAPADRKEVADLSRDLLQFVASKVPYSLRRLTGLEVQ
SLYVGPQTITT-APSLPGLFGSSPLSPHPTKGGYAVTDFLTYNCLASDTDLYSDCLRTFW
TCPHCGLHMPLTPLERIAHENTCPEAPQDSPPGA----EEAAPEPLQK-TSALQRPYHCE
ACQKDFLFTPTEVLRHRRQHM---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MASSKRPEGRG--------------SREPRDSEHWDWGCPETRSQLEELFFGDQD
VIRRGSDECHKFWAFFDRLQTFQKLKPGPEGERP-A----KAQAPQGPECPALADLPATY
DPRYRINLALLSGEGEPG-LG------QRGTRSRLPRDRLAEFRRALLHYLDFGQKQSFG
KLAKLQRERAALPMARYRQHLLRALGEHQVV-IVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQYGSQVSWHGRAAPGMKGPVICMGNFTALTIAKPL
VPIFHLLPPTPSHRCYLPKFFLWAYLY-LLLC-------LYLSLSVSLLSFSL-------
------------------------------------------------------------
FSA

PF00271 // ENSGT00910000144017_3_Domain_1 (544, 656)

QLHISAAFQ---------------------LGEVMGKVFDVAPPGVRKCILS----T
NIAETSVTIDGVRFVLDSGKVKEMSFDPQAKLQRLQEFWISRASAEQRKGRAGRTGPGVC
YRLYAESDYDDFAPYPVPEIQRVALDALVLQVR---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRG-----HRDRDHHRAPREEEAPEKWDWNCPETRCLLEDVFFRDED
YIRRGSEECQKFWAFFERLQRFQHLKTSQK--KE-K----DPGMPKHGI-AALADLPLTY
DPRYRINLSILS--P-DT-RG------RHGPGRELPPERVSEFRRALLHYLDFQQKQAFG
RLAKLQRERAALPIAQYGNRIL

PF00270 // ENSGT00910000144017_3_Domain_0 (323, 467)

QTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-QRLLPQRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 532)

NISLFSSYFSHAPV
VQVP-GRLFPITVVYQLQEA-E--QTASKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEITTVLDAAQAYASLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SVE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLQEQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SNLDCATARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSGNS---RKWCRRRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLEDHG
LLSGAQVVAPGDSYSRLQQRRERRALHQLKRQHE-EGGGRRRKVLRLQE--DGCSSDEED
R---EGSASQRADSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLALLKLVLGRGLYP
QLAVPDAFNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFANSPEVLHTQGQEA
---SGQEG-SQDGRDQMSCKHQLLAFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSIDT
NGDCSRLVADGWLELQLADSES-AVRLLATSLRLR--AHWESALDRQ--------LAHQA
Q-RRKL----------EQEEDVGSPAVSPQEVAALSRELLQFMAAKVPYRLRRLTGLEAQ
NLYVGPQTITT-APSLPGLFGNSTLSPHPTKGGYAVSDCLTYNCLTSDTDLYSDCLRSFW
TCPHCGLHMPFTPLERIAHENTCPEAPGDDP-GK----SEAASAPPQK-TSALQRPYHCQ
VCGQDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTRDERD-----RRDRRHHRAPREEEALEKWDWDCPETRRLLEDTFFCDED
YIRRGSEECQKFWAFFERLQRFQHLQASRK--QE-K----DPGRPTHGV-PALADLPHTY
DPRYRINISILG--P-DT-RR------GQGPARLLPPERVSEFRRALLHYLDFVQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKENQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPT
LPQYQVLIVDEVHERHLHNDFLLGIL-RGLLPRRPDLKVILMSATINISLFSSYFSHAPV
VQVP-GRLFPITVVYQPQEA-E--QTASKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLDAAQAYASLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSTQ--SSLDCATARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSGNS---RKWCRHRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLEDHG
LLSGAKVVAPGDSYSRLQQRRERRALHQLKRQHE-EGGGRRRKVLRLQE--DGCSSD-ED
N---EGSASQRADSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLALLKLVLGRGLYP
QLAVPDAFNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFANSPEVLHTQGQET
---SGREG-SQDGKDLMNCKHQLLAFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSIDT
NGDCSRLVADSWLELQLTDSES-AVRLLATSLRLR--AHWESALDRQ--------LAHQA
Q-RQRL----------EQEKEVESPAVSPKEVAALSRELLQFMATKVPYSLRRLTGLEAQ
NLYVGPQTITA-APNLPGLFGNSTLSPHPTKGGYAVSEFLTYNCLTSDTDLYSDCLRSFW
TCPHCGLHMPFTPLERIAHENTCPEVPKDDP-GS----EEAAPAPLQK-TSALQRPYHCQ
VCGEDFLFTPTEVLKHRRQHL---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPCTY
DPRYRINLSVLG--P-DT-RG------SQGLGRRLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNR

PF00270 // ENSGT00910000144017_3_Domain_0 (321, 467)

ILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-K--PTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVF
LSGMAEISTVLEAAQTYASHTQRWVVLPLHSALSVADQDKVSQLECSGIIEAHCS----L
DFLGSSDPLSLVPQVATIGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1135)

RQ-FKELLEDHG
LMTGAQATQVGDSYSRLQQRRERRALHQLKRQHD-EGAGRRRKVLRLQEEQDGGSSEE-D
R--AGPAPPGAGDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLALLKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEP--
--EAGSCDGSRDDKDKMSSEHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ARWEGALDRQ--------LAHQA
QRRL------------EEE--EQDAPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NLYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLEHIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTRDARDH-------RDHRRAPSEEEAPEKWDWSCPETRRLLEDAFFRGED
PIRQGSEECQRFWAFFERLQRFRSLKASRQ--EE-A----DPGHPTHSI-PALADLPRAY
DPRYRINLSVLG--P-DT-RG------SRELGRCLPPERASEFRRALLHYLDFSQKQAFA
RLAKLQRERAALPIAQYE

PF00270 // ENSGT00910000144017_3_Domain_0 (319, 467)

KRILRTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSKVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPQRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLQAIDNKYPPEERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGNPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLQDQGALDSSESLTPIGSLL-------------AQLPVDVVI----G
K-MLILGSVFSLAEPMLTVAAALSVQSPFTRSAQ--SSLECAAARRPLESDQGDPLT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
IFN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1135)

RQ-FKELLEDHG
LLAEAQLVAPGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEDLGDCSSEE-D
C--AGR---AADDNVDIQDVKFKLRHNLEQLQAAASAAQD-LSREQMALLKLVLGRGLYP
QLAVPDALNSG--------RKDSDQVFHTQAKQGTV---LHPTCVFANNPEVLHTQER--
--ETAGGEGKQGDKDKMNSSHQLLAFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLTASLRLR--AHWESALDRQ--------LAHQA
RRQH-------------------APPISRKEVAALSRELLQFMASKVPYSLRRLTGLETQ
NLYVGPQTVTA-APSLPGLFGSSTLSPHPIKGGYAVTDFLTYNCLTSDVDLYSDCLRSFW
TCPHCDLHLPLTPLERIAHESSCPQAPQEGTAGG----EEVAPEPVQK-ASALQRPYHCE
ACQKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPSPGTREGRDR-------RDHHRAPSAKEAPEKWDWNCPETRGLLEDTFFGDGG
CIRRGSEDCQKFWTFFERLQRYQSLRPSRK--EE-T----EPGSPPHGL-PALADLPRTY
DPRYRINLSILG--P-DP-RG------SRGLATRLPPERVSEFRRALLHYLDFGQKQAFA
RLAKLQRERAALPIAQYGRRLL

PF00270 // ENSGT00910000144017_3_Domain_0 (323, 467)

QTLAEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVAFESLSQYGSQVGYQIRFESTRSSATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHSDFLLGVL-HHLLPRRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 532)

NIELFSSYFGHAPV
VQVP-GRLFPITVVYQPQEA-E--PATSKSEKLDPRPFLRVLETIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISSVLEAAQTYASHTQRWIVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 732)

GPGVC
YRLYAESDYDAFTPYPVPEIRRVALDTLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAI

PF04408 // ENSGT00910000144017_3_Domain_2 (732, 822)

LYLRDQGALDSSEALTPIGCLL-------------AQLPVDVVI----G
K-MLILGAMFSLAEPVLTVAAALSVQSPFTRSAQ--GSLEC

ENSGT00910000144017_3_Linker_2_3 (822, 889)

AAARRPLESDQGDPFTLFN
VFN--AWVQVKSERGGNS---RRWCRRRGVEE-QRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1137)

RQ-FKELLEDHG
LLAGAPG-----GSSRLQERRERRALQQLKRQHE-EGAGRGRKVLRLREDRAAGSSDEDD
P--AGPGAPDGGGGVDIQDVKFKLRHNLAQLQVAASAAQD-LSGERLALLKLLLTRGLYP
QLAVPDAFNSG--------RKDSDQVGPLSTSVPAPTPTQAPCGGWTAGPEGKR---PE-
--GFLEEGPGQEVGDGMSRSHQLLTFVSLLE-TNKPYLVNCVRVPALQSLL-LLSRSLDT
SGDCSRLVADGWLELRLADSES-AVRLLATSLKLR--ARWESALDQQ--------LARQA
LRRPE-----------EEEEEEERLPIHSKEVAALGRELLQFMASKVPYSLRRLTGLETQ
NLYVGPQTVTT-APSLPGLFGDSTLSPHPTKGGYVVTDFLTYNCLVSDTDLYSDCLRTFW
TCPHCGLHLPLTPLERMAHENTCAQAPQEDG-------AEEAPAPIQK-ASALQRPYHCD
TCGQDFLFSPTEALRHRRQHL---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DAGQPKHSI-PALADLPRAY
DPRYRINLSVLG--P-DT-RG------SQELGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAVQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKVQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LMTGAQATQVADSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSEE-D
R--AGPDPPGAGDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEP--
--EASSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ARWEGALDRQ--------LAHQA
QRRL------------EEE--EQDVPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NLYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLRK-TSVLQRPYHCE
ACGRDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRARESGEP-------RARHRAPREEAARQSWDWTCPETRRLFEEAFFGEGD
YIRQGSEECQKFWTFFEHLQRFHSLRTARREEQD-------HG-RATSKAPAFADLPRTY
DARYRINLSVLGPD----TRG------SRGPGGQLPPERVSEFRRALAHYLDFGQKQAFG
RLAKLQRERAALPIAQYGQRLKRMLKEHQVV-VVAGDT-WSKSTQAPQYLLPAGFSHVAC
TQPRRIACISLTKRVGFE-LSQYDAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXVIYQPPETEAA-GAASKPEKLDPRPFLRVLEAIDHKYPAEERGDLLVF
LSGMAEISAVLEAAQVY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

AASTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDAQAKLQRLQEFWISQASAEQRKGRAGRTGPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-----XXXXXXXX--XXXXXXXXXXXXXXX-------------XXXXXXXXX----X
X-XXXXXXXXXXXXXXXXXXXXXXXXX-XX-------X-XX---XXXXXXXXXXXXXXXX
XXX--XXXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXELLEDHG
LLAGARAPEQGDSYSRLQARRER

PF07717 // ENSGT00910000144017_3_Domain_3 (924, 1066)

RALYQLKRQHD-VGGGRRRKVLRLDEGLDGGSSDE-E
P--DRKAAGETGDSVDIQDVKFKLRHSLEQLQAAARSAQD-LSRDQLALLKLVLARGLYP
QLAIPDPLNSN--------RKDSDQIFHTRAKQGTV---LHPTCVFTNSPEVLHPQEPEA
SEGRQ-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MAPPRPREGRGH-------RDHRWAPSEEEALEKWDWDCPETRRRFEDAFFRDED
YIRQGSEDCHKFWAFFERLQRFQTLKTSKK--EE-T----DPGHPKHCV-PALADLPRPY
DSRYRINLSVLG--P-DM-RD------IRGSGSQLPPKRVSEFRRALLHYLDFSQKQAFT
RLAKLQRDRAALPIAQYRKCIL

PF00270 // ENSGT00910000144017_3_Domain_0 (323, 467)

QTLKQHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYKVLIVDEVHERQLHNDFLLGVL-QHLLPTRPDLKVVLMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 531)

NIMLFSSYFGNAPV
VQVP-GRLFPITVIYQPQEA-E--QTASKSERLDPRPFLRVLEAIDNKYP

PF00271 // ENSGT00910000144017_3_Domain_1 (531, 656)

AEERGDLLVF
LSGMAEIGAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 842)

AIQYLQEQGALDASEALTPIGCLL-------------AQLPVDVVIVPPPG
K-MLILGSMFSLAEPVLTIAAALSVQSPFPRSAQ--SSLECAAARQPLDSDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 891)

FN--AWVQVKAERSQNS---RKWCRRRGVEE-HRLY-----EMANLRRQ

PF07717 // ENSGT00910000144017_3_Domain_3 (891, 1137)

-FKDLLEDHG
LLAGAEAATPGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEAEDGSSDE-D
H--AGPSARHAEDSVDIQDVKFKLRHNLEQLQAAASSAQA-LSREQLVLLKLVLARGLYP
QLAVPDPFNSG--------RKDSDQIFHTQAKQGAV---LHPTSVFASSPELLHVQEP--
--QATCGGGSRDDKDKMSSKHQLLTFVSLLE-TNKLYLVNCVRVPALQSLL-LFSRSLDT
NGDCSRLVADSWLELQVVDSEG-AVQLLAAALRLR--ACWESALDRQ--------LSHQ-
--------QRRQRLGEEDEDEEEAESVSRAEVAALSRELLQFMATKVPYSLRRLTGLEAQ
NLYVGPQTVTA-TPKLPGLFGSSALSPHPTKGGYRVTNFLTYNCLLSDTDLYSDCLRTFW
TCPRCDLHLPLTPLERMAHESACATDL-HG---A----EEATTEQSRK-PSALQRPYHCD
SCQKDFLFTPTEALRHRRQHM---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTWEGRGP-------RDRPPAPSQEEDPEKWDWNCPETRRLFEDAFFGDED
YIRQGSEECQKFWTFFERLQRFQNLKTTRK--EE-K----DSRHPKHSI-PALADLPRAY
DPRYRINLSVLG--P-DA-RR------SRGLGRRLAPERVSEFRQALLHYLDFGQKQAFG
RLAKLQRERMALPIAQYGDRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPR
LPQYQVLIVDEVHERHLHNDFLLGIL-RRLLP-RPDLRVILMSATINISLFSSYFGMPLV
XXXX-XXXXXXXVVYQPQEA-E--PTTSKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVF
LSGMAEISAVLEAAQTY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ASHTQRWAVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDP-AKLQRLHEFWISASA--EQRGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GP--V
CRLYAESDYDAFAPYPVXXXXXXXXXXXXXXMKGM--------SVGDPRTFPFIEPPPPT
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAICYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFHLAEPVLTIAAALSVQSPFTRGAQ--SNPECVAARRPLESDQGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

FN
ENXXXXXXXVKSERSRNS---RRWCRHRGIEE-HRLY-----EMA-LR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLEDHG
LLARAQASKPGDSYSRLRQRRERQALYQLKRQHE-QGQGRRRKVLRLQEDQDGCSSDE-D
R--GGAASQGGGDNVDIQDVKFKLRHNLEQLQAAASSAQA-LTRDQMALLKLVLGRGLYP
QLAIPDPFNSG--------RKDSDQIFHTKTKQGAV---LHPTCIFANSP-VLHTQEQ--
--EARGSDGSRDDKDKMSSRHQLLAFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCCRLVADGWLELQLVDSES-AVRLLAASLRLR--AHWESALDRQ--------LAHQA
RWRMED--------KDD----EETDPVNRKEVAALSRELLQFTASKVSYSLRRLTGLEIQ
NLYVGPQTITA-APSLPGLFGCSTPSPHPTKGGYAVTDFLTYSCLTSDADLYSDCLRTFW
TCPHCDLHMPFTPLERIAHESTCPEAPQDGPPGA----EEAAPEPLQK-ASALQRPYHCE
ACQKDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDH-------RDRPRAPREKEAPEKWDWNCPETRRLFEDAFFRDED
YIRQGSEECQKFWTFFERLQKFQHLKTARK--EE-K----DAGPPERSI-PALADLPRAY
DPRYRINLSVLG--P-DP-RG------SRGPGGRLPRDRVSEFRRALLHYLDFGQKQAFG
RLARLQRERAALPIAQYASRI

PF00270 // ENSGT00910000144017_3_Domain_0 (322, 467)

LQTLERHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSQVGYQIRFESTRSPATKIVFLTVGLLLRQLQREPR
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPQRPDLKVVLMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NISLFSSYFGDAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLEAIDSKYPPEERGDLLVF
LSGMAEISAVLEAAQPYASHTQRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSCDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSTFCLAEPVLTIAAALSVQSPFTRSAQ--GNPECAAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
IFN--AWVQVKCERSSNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1135)

RQ-FKELLEDHG
LLAGAQALEPGDSYSRLRQRRERQALFQLKRQHE-EGGARRRKVLRLGD-QDGGSSDE-D
P--ARPASQGAGGSVDIQDVKFKLRHNLEQLRVAASAAQA-LSREQLALLKLVLARGLYP
QLAAPDPFNSG--------RKDSDQIFHTQAKQGAV---LHPTCVFASSPEVLHTREP--
--EARGGEGSRDDKDKMSSRHQLLAFVSLLE-TTKPYLVNCVRVPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVGLLAASLRLR--TRWEQVLARQ--------LARQA
RRRPEE---------EEEDEDEEEAAVHRREEAALSRELLRFAASQVPYSLRRLMGLEIQ
NLYVGPQTITA-APSLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERVAHENSCPQAPQDGAPGA----EEAAPEPPQK-ASALQRPYHCE
ACQQDFLFTPTEVLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
MTTPSMPPPRTKEGRDH-------RGRHWDPSEEEAPEKWDWNCPETRHLFEDAFFREED
YIRQGSEECQKFWSFFERLQRFQNLKTARK--GE-K----DPAPPKHSV-PALADLPRTY
DARYRINLSVLG--P-DT-RG------SRGLGR-QPPERVTEFRRALLHYLDFSQKQAFG
RLAKLQHERAALPIAQYGNRIL

PF00270 // ENSGT00910000144017_3_Domain_0 (323, 467)

QTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSQVGYQIRFESTRTAATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 565)

NISLFSSYFGTAPV
VQVP-GRLFPITVVYQPQEA-E--PVASKSEKLDPGPFLRVLEAIDNKYPPEERGDLLVF
LSGMAEISSVLEAAQTYASRTQRW

PF00271 // ENSGT00910000144017_3_Domain_1 (565, 656)

VVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMGYDPQAKLHRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLQDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFHLAEPVLTIAAALSVQSPFTRSAQ--SNPECAAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSRNS---RKWCRHRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1137)

RQ-FKELLEDHG
LLARAQAPTPGDSYHRLQQRRERRALYRLKRQHE-EGGGRRRKVLRLQEDLDGCSSDE-D
R--------GAGDSVDIQDVKFQLRHSLDQLQAATSSAQD-LTRDQMALLKLVLGRGLYP
QLAVPDPFNSS--------RKDSDQIFHTQSKQGTV---LHPTCIFANSPEVLHAQEQ--
--EARGSEGSQDDKDKMSSKHQLLTFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASVRLR--AHWESTLDQQ--------LARQA
RRRGPG---------VDQEE--EEAPVDPKEVAHLSRDLLQFVASKVPYSLRRLTGLEVQ
NLYVGPQTITA-APSLPGLFGSSALSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHMPLTPLERIAHENTCPEAPQDAPPEA----EDTAPEPLPK-ASALQRPYHCE
ACQKDFLFTPTEVLRHRRQHMKRQRPVVGPPHSPALILLAAACHPRLPGPDLGR------
----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
RSNSKVSCP-------VARRRDREKEVGYQIRFESTCSSATRIVFLTEGLLLRQAQREPT
LPGYRVLIADEVHERHLHCDFLLGVL-RRLLPVRPDLKLVLMSATINIRLFADYFGGAPV
VQVP-GRLFPITVLYEPIRPEES--ASGRKERLDPRPYLRVLQAIDHKYPPEERGDLLIF
LSGVAEIGAVMEAAQTYATHTQRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSTLSVAEQDKVFDLPPPGVRKCIVS----T
NIAETSVTIDGVRFVVDSGKVKELSYDPKAKLQRLQEFWISCASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDAFAPYPVPEIQRVALDALVLQMKSM--------GLGDPRAFPFLEPPPPA
SLK-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 839)

AVGYLKHQGALDAEESLTPIGSLL-------------AELPVDVVI----G
K-MLVLGTLFGLAAPTLTAAAVLSVPSPFLRSSSGRSDPDCATARRPLESPLGDPLTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

LN
VFD--AWVQEKSDNRGGS---RRWCRRRGLEE-HRLY-----EAANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1134)

RQ-FQELLRDHR
LLEPAS-RPR-DSYTRQSRHRHRRELHKIKREHE-QGEGRRRKVLRLQEEEGGSSSGDE-
--------GDAKRGPDIQDVKFQLRHNVDELRSAASLGQA-LSSGQLSLLQLVLGRGLYP
QLAVPDPYNKT--------RKDSDQIFHTKEKVGVV---LHPTSVFASSPELLQASQERG
---FEHQAHRDAAKEGLSSRHQILAFVSLLE-TNKPYLVNCLRLPALQALL-LLARSLDT
SADCNRIVADSWLELRIPAAEM-ALRLLRGTLRLR--ASWEKILDRQ--------LESRA
GQG-------------KDEEEAEERRPSAREVHRLTQELLEFLKTEVQYSLRRLTPLEQQ
NLYVGPQMVAAGREGLSQLFQGAEMIPDEVKGGYRVGDFLTFNCLAGEGDLYSECLRSFW
TCSRCGLYMPFTPLERVAHEDTCQVPGPETETSPGDPTEDAAVAPTPGASSALQQSYHCA
VCQQNLLLTPTEILRHRKQHQTAPS-----------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRGHR------DHHPRATREEETPERWDWSSPETRSLLEDAFFRDED
YIRQGSEECQKFWTFFERLQRFQNLKTATRR-EE-K----DPGYPKRSI-AALADLPDTY
DPRYRINLSILG--P-DT-GG------FRGQGGRLPPERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGSR

PF00270 // ENSGT00910000144017_3_Domain_0 (321, 467)

ILQTLREHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQMQREPS
LPQYQVLIVDEVHERHLHNDFLLGIL-RRLLPRRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NISLFSSYFGSAPV
VQVP-GRLFPITVVYQPQEA-E--PAASKSEKLDPRPYLRVLEAIDNKYPPEERGDLLVF
LSGMAEISTVLEAAQTYASHTQRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLQDQGALDGSEALTPIGSLL-------------AQLPVDVVI----G
K-MLLLGSLFRLAEPVLTVAAALSVQSPFSRSAQ--SSPECAAARRPLESDQGDPFTLFN
VFN--AWVQVSDGQSKAP---CGQSPSQWVEIT------HCFNYCSFEVG-FEELLEDHG
LLARAQASKAGDSYSRLQQRRERQALYQLKRQHE-EGGGRMRKVLRLQEDQGGGSSDDEP
A--APPGGTACTSRAD---VRVTA--SL---QEAAFTGRSPAPAGAKALVTL-ARRAHFE
SQLCPDQNHRQVEVERDNSVERSADKHHLLARLGNC-------------KQKISSHNKKQ
-----EESAKPNEQTKHADETQHLRWPAALEGGARPMLLP--SLPSPQSLL-LFSRSLDT
SGDCSRLVADGWLELRLADSEV-AAQLLAAALRLR--ARWERALDQQ--------LARQA
RRRL--------------EEEEEAPGVDPKEVAVLSRELLQFSASKVPYSLRRLTGLEAQ
NLYVGPQTITA-TPGLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLASDTDLYSDCLRSFW
TCPQCGLHAPLTPLERIAHENSCPEAPREGPPGA----EEAAAEPPQK-ASALQRPYHCA
VCQEDFLFTPTEALRHRKQHA---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRGREGRDH-------RDHHWTPSEEEAPEKWDWNCPETRRLLEDAFFRDEN
YIRQGSEECQKFWTFFERLQRFQTLKTSKK--EE-K----DPGSPKHHI-PALADLPRTY
DPRYRINLSILG--P-DT-RG------SRGPSSRLPPERISEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISIVLEAAQTYANHTQRWVVLPLHSALSVADQDKVFDVAPSGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 732)

GPGVC
FRLYAESDYDSFAPYPVPEIRRVALDALVLQMKSM--------GVGDPRTFPFIEPPPPA
SLE-----TAI

PF04408 // ENSGT00910000144017_3_Domain_2 (732, 838)

LYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFNLAEPVLTIAAALSVQSPFTRSAQ--NSLECAAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSRNS---RKWCRRRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1137)

RQ-FKELLEDHG
LLAGVQAVTPGDSYSRLQQRRERRALHQLKRQHE-ESGGRRRKVLRLQEEPADFSSDE-E
H--AGPAPRGAEDSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLAMLKLVLGRGLYP
QLAVPDAFNSG--------RKDSDQVFHTQAKQGAV---LHPTCVFASNPEVLHAQEQ--
--EAAGPTGSRDDKDKMSSKHQLLTFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVQLLAASLRLR--AHWESALDQQ--------LSYQA
RRRQ------------LEEEEEMTAVVSRKEVAALSRELLQFMTSKVPYSLRRLTGLEAQ
NLYVGPQTITA-APSLPGLFGSSTLSPHPTKGGYTVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHMPLTPLERIAHENTCPEAPQDLAPGT----EEATPKPLQK-ASTLQRPYHCE
ACQKDFMFTPTELLRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRGH-------RDHHRAPHEEETPERWDWNHPETRRLLEDTFFRDEE
YIRQGSEECQKFWAFFERFQRFQNLKTARK--EE-Q----DPGPPKHSI-PALADLPRTY
DPRYRINLSVLG--P-DT-RG------SREPGRRLPPERVAEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGKRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPQRPDLKVVLMSATINIALFSSYFGGAPV
VQVP-GRLFPITIVYQPPEV-E--PATAKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVF
LSGMAEISAVLEAAQTY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ASHTQRWVVLPLHSTLSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SLGDPRAFPFIEPPPPA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLRDQGALDGTEALTPIGSLL-------------AQLPVDVVI----G
K-MLVLGSTFHLAEPVLTIAAALSVQSPFTRSAQ--SNPECAAARRPLESDQGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

FN
IFN--TWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1133)

RQ-FKDLLEDHV
LLAGTEAPRPGDSYSRLQQRRERQALYQLKRQHE-EGAGRRRKVLRLQEEQDGASSDE-D
R--GATADQDSCDSVDIQDVKFKLRHNLEQLQAAASSAQD-LSRDQMALLKLVLGRGLYP
QLAVPDPFNSG--------CKDSDQIFHTQTKQGTV---LHPTCVFAGSPEVLHTQEP--
--ESRASDGSRDDKDKMSSKHQLLTFVSLLE-TNKPYLVNCVRVPALQHSNNVYDRDFEE
LGHV-IVGPEGYTELKVQDDFLEEWRDLRTKGRVPKGWRWKGQIQTS--------NREQG
RG---L---------QEQ-----LDP-GADGVSESTSHHILSLFPQVPYSLRRLTGLEVQ
NLYVGPQTITA-APSLPGLFGSSTLSPHPSKGGYTVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCDLHMPFTPLERITHENTCPNAPQGGSPGA----EEADPEPLQK-ASALQRPYHCE
TCQKDFMFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MAAPRAREARGH-------RDHRRVPSEEEALEKWDWDRAETRRLFEDAFFRDED
YIRQGSEDCHKFWAFFERLQRFQSLQTSRK--EE-K----DPRHPKHRI-PALADLPHTY
DPRYRINLSVLG--P-DM-RD------T-GRGSRLPPKRVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGDCILQ

PF00270 // ENSGT00910000144017_3_Domain_0 (324, 467)

TLKQHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYKVLIVDEVHERQLHSDFLLGVL-QRLLPTRPDLKVVLMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 530)

NIALFSSYFGNAPV
VQVP-GRLFPITVIYQPQEA-E--QTASKSEKLDPRPFLRVLEAIDNKY

PF00271 // ENSGT00910000144017_3_Domain_1 (530, 656)

AAEERGDLLVF
LSGMAEIGAVLEAAQTYASRTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIEGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AIQYLRDQGALDASEALTPIGCLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SSLECAAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKAERSRNS---RKWCRRRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1137)

RQ-FKELLEDHG
LLAGAQEATPGDSYSRLQQRLERRALHQLKRQHE-EGAGRRRKVLRLQEEADDGSSDE-D
R--AGPAARRADDSVDIQDVKFKLRHNLEQLQAAASSAQA-LTREQLLLLKLVLARGLYP
QLAVPDPFNSG--------RKDSDQIFHTQAKQGAV---LHPTSVFASSPEVLHTEEP--
--PATGAGGSRDDKDKMSSKHQLLAFVSLLE-TNKLYLVNCVRVPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLVDSEG-AVRLLGAALRLR--ARWESALDRQ--------LSHQA
WQQQR---QRRQ---RLEEDEEEAAPISRTEVAALSRELLQFMATKVPCSLRRLTGLEAQ
NLYVGPQTVTA-TPSLPGLFGSSTLSPHPTKGGYSVTDFLTYNCLSSDTDLYSDCLRTFW
TCPRCDLHLPLTPLERVAHESACAAGL-DGGPGA----EEAAPEQPQK-PSALQRPYRCD
ACHRDFLFTPTEALRHRRQHM---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDH-------RDHHRAPREEETLEKWDWNCPETRRLLEDAFFHEEG
CIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGHPKHSI-PALADLPHAY
DPRYRINLSVLG--P-DP-RG------CRGPGRRLPPERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGTRILKTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFGSAPV
VQVP-GRLFPITVVYQPHEA-E--PTTSKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTRRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 733)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAIF

PF04408 // ENSGT00910000144017_3_Domain_2 (733, 842)

YLQDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFNLEEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--TWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKDLLEDHG
LLARAQATKAEDSYSRLQQRRERRALYRLKRQHE-EGGGRRRKVLRLQEEQAGCSSDE-D
R--AGPASQGSADSVDIQDVKFKLRHDLEQLQAAASSAQD-LTCDQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLARGLYP
QLAIPDVFNSG--------RKDSDQIFHTRAKQGTV---LHPTCVFASSPEVLHTREQ--
--EAGGCEGSREDKDKMSSKHQLLTFVSLLE-TNKPYLVNCVRVPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADAES-AVRLLAASLQLR--ARWEGALDRQ--------LAQQA
GPR-------------PQEEEEEALPTSPKEVAALSRDLLQFMASKVPYSLRRLTGLETQ
NLYVGPQTITA-APNLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDADLYSDCLRTFW
TCPHCGLHMPFTPLERIAHENTCPEAPQDGPPGA----EEAAAEPLQK-ASALQRPYCCE
DCQKDFLFTPTEVLRHRKQHL---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPLRTREGKGL-------RYHHRALCEEEASEQWDWNSPETRRLFEDAFFGDED
YIRQGSEECQKFWSFFERLQRFQTLKLLRKGDENVK----KPPGPPIPGLPALADLPHTY
DPRYRINLSILGPDP----RV------SRERGRHLPPDMLAEFSQAMLHYLDYGQKQAFV
RLDKLQRERAALPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXX-XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXVVYQPPEVE---PTPAKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVF
LSGLAEISAVLEAAQTYATHSQRWVVLPLHSTLSVASQDKXXXXXXXXXXXXXXX----X
XXXXXXXXXXXXXXXXXXXKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------DVGDPRTFPFIEPPPPA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLRDQGALDSAEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSVLQLAEPVLTIAAALSVQSPFTRSAQ--SNPECAATRRPLDSDQGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 982)

FN
VFN--AWVQXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX--XXXXXX---X-XXXXXXXXXXXXXXXXXXXXXXXXX
X--XXXXXXXXXXXXXXXDVK

PF07717 // ENSGT00910000144017_3_Domain_3 (982, 1070)

FKLRHNLEQLQAAASSAQD-LSRDHLALLKLVLGRGLYP
QLAIPDPFNSG--------RKDSDQFFHTQTKQGTV---LHPTSVFASNPEVLHPREPES
RA----GDGNQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX--XXXX
XX---XXXXXXXXXXXXXXXXX-XXXXXXXXXXXX--XXXXXXXXXX--------XXXXX
XXXX----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPYRLRRLTGLEVQ
NLYVGPQTVTA-APSLPGLFGSSTPSPHPTKGGYTVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHMPLTPLERIAHENTCPDAPQASAPGA----EEAALELLQK-TSALQSPYHCE
TCGKDFLFTPTRVLRHRKQHA---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRGP-------WDRPRAPSPEAAPEKWNWNCPETRRLFEDAFFGDED
YIRQGSEECQKFWTFFERLQRFQNLKTTRK--EE-K----DARQPKHSH-PALADLPRAY
DPRYRINLSVLG--P-DA-RD------SRGPGRRLPPERASEFRQALLHYLDFCQKQAFG
RLAKLQRERAALPIAQYGHHI

PF00270 // ENSGT00910000144017_3_Domain_0 (322, 467)

LQMLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGCSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQMQREPS
LPQYQVLIVDEVHERHLHNDFLLGVL-QRLLPQRPDLKVVLMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVF
LSGMAEISAVLEPAQAYASHTQRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPT
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 839)

AILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFHLAEPVLTIAAALSVQTPFTRSAQ--SNPECAATRRPLESDQGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

LN
VFN--TWVQVKSERGRNS---RKWCRHRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1135)

RQ-FKELLEDHG
LLAGAQAPQPGDSYSRLQRRRERQALYELKRRHE-EGVGRKRKVLRVQDDQDGWSSDE-D
R--GGSASRGAGDSVDIQDVKFKLRHNLEQLHAAASSAQA-LTRDQMALLKLVLGRGLYP
QLAVPDPFNSS--------RKDSDQIFHTQTKQGVV---LHPTCVFTNSPEVLHAQEQ--
--AARGSDGSRDDRDKMSSKHQLVTFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADTES-AVRLLAASLRLR--AHWESALDRQ--------LAHQA
RRRLED--------EEE---EEEEAPVNHKEVAALSRELLQFMTSKVSYSLRRLTGLEAQ
NLYVGPQTITA-APSLPGLFGNSTPSPHPTKGGYAVTDFLTYNCLTSDADLYSDCLRTFW
TCPHCGLHMPLTPLERIAHENTCPEAPQGGPPGA----EEAAPEPPQK-ASALQKPYHCE
ACQKDFLFTPTEILRHRRQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
--------------------------MRSDDEGSPPRSGWDWSCPRVRRRVEEQHFGPGG
LLPCSPEDIHNFWAFFERLRRFQSQKPPPAPTPK----------SPKQNPSPPLGLPPRY
DPLHRINITLPEP--------------QTQHGPSIPRRHRAELRCALLHYLDFTQKQSFS
KLAKIRQGRTALPIARFREPILSAVGRHRVV-LVAGDTGCGKSTQVPQFLLEAGYQNVAC
TQPRRIACVALAKRVAYESLRQHSGQVSYQIRFDTTRSPSTQILFLTEGLLLRQAQRDPQ
LSGYHVLIIDEVHERHLHADVLLGVL-RRLLPTRPDLRLLLMSATINIELFTHYFGGAPV
VQVP-GRSYPISVIYTPIPKEEQEVTPSRWERLDPRPYVRVLESIDQRYPA

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGVMEIGVVMEAAQGYAERSGRWVLLPLHSALPVTEQDKVFDVPPPGVRKCILA----T
NIAETSVTIDGVRFVLDSGKVKEMSYDPQCKLQRLQEFWISRASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGLC
FRLYSESDLEAFAPYPVPEIQRVALDSVVLLLKSM--------GLGDPRSFPFLDPPSPS
SLE-----S

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 833)

ALRYLHAQGALDDTEELTPIGTLL-------------AQLPVDVVL----G
K-MLVLGSLLALADPTLTVAAVLSVPSPFLRLS----DPERAAARRALESPHGDPLTLLN
AFN--EWVKVKSRRAGGS---RKWCRRCGLEE-HRLY-----EAANLRRQ-FQELLRDHH
LIDPPP-NDP-R---TPTQRRERRALHRLYRSHG-GTAPRPRKVLRLHHGTAASSGGEEE
E--EEEAGGSGEHSVDIQDVKFQLRHNVAELQAAS--NSV-LSTSHLSLLKLVLCRGLYP
QLAIPDPLNDS--------RKDSDQVTP--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDGDRESQRWNWDCPNTRRQLEELFFSEQG
YIKANSEDSKEFWVFFDRFQRFQKMQKRGDKCKGRT--------DKEKYSGSLKDLPKVY
DPRYRINFSIIQSKDVEKSRHNHVKEYRSRDCRSIPREKLEEFKMSVLHYLDFTQKQSFA
KLVKLRKERSSLPIFQYKEKIISMVHKHQVV-VVAGDTGCGKSTQVPQYLLAAGFGHIAC
TQPRRIACISLAKRVGFESLNQYGSKVGYQIRFESSRSPATKIVFITEGLLLRQIQRDST
LPQYQVIIVDEVHERHLHSDFLLGVL-RQLLILRPDLKVILMSATINIKLFSGYFEQAPV
LQVP-GRLFPIQVIYQPIPQEET---VSKSEKLDPRPYLHVLQAIDHKYPPDERGDLLIF
LSGVTEISSVQEAVQVY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ATHTQRWIVLPLHSTLSIADQDKVFDLAPVGVRKCIIS----T
NIAETSVTIDGVRFVLDSGKVKEMSFDPKAKMQRLQEFWISRASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
YRLYAESDYDAFSPYPVPEIQRVALDSLVLQMKSM--------ELGNPRHFPFIEQPSMS
SIE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAIFYLRDQGALDINEELTPIGKLL-------------AKLPVDVVI----G
KKMLILGSLFSLVEPVLTIASALSVQSPILRNST--SNPEWGTARKPLESEHGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

LN
IFN--EWVQVKANQRSNS---RKWCRRRGLEE-QRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1138)

RQ-FKELLKDHG
LLEENV-AQRGDRNSRQRQHKERKELHQLKRQHE-RVEKRKRKVLKLQDEGAGSSSDGEE
QYHTEKHRKDRKDSIDIQDVKFKLRHNIHELHASSSTGQD-LSSQEVSLLKLIVCHGLYP
QLGVPDSFNSC--------RKDSDQVFHTKNKQGVV---LHPTCVFSCNPELLQVNSEEE
------SAGNESGNKGQSSRHQIVAFVSLLE-TNKPYLVNCVRLSALQGFL-LLARCIDT
SADCCRIVCDKWMEMNVDNPES-ALCLITEAVQLR--VALEKLLKSR--------LEKPS
RRE-------------DH--TEDDAWTARQEAERLGRRLVDYVRPEAIYSMRRLAALEAQ
NLYVGPQVLSS-ASGLPGVFTGVELKPDPLKGGYSVTNFLTYNCLASETDFYSDCLRSFW
TCPHCGLYMPFTPMERMSHQNSCMVEETSEGLGEQ----DN----KMTSVTSLHRNYHCD
ICQKDLMLTPTEILKHKRQHLNS-------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MASPSGREGRGH-------RDHHRAPREEETSERWDWNHPETRRLLEDTFFRDED
YIRQGSEECQKFWTFFERLQRFQNLTTAREG-KE-K----DPGSPTRSI-PALTDLPRTY
DPRYRISLSVLD--P-DT-RG------SRELRRRLPPERVAEFRRALLHYLDFGQKRAFG
RLAKLQRERAALPTAQYGKRILQAVKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPR
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPQRPDLKVVLMSATINIALFSSYFGGAPV
VQVP-GRLFPITVVYQPPEV-E--PTATKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVF
LSGMAEISTVLEAVQTY

PF00271 // ENSGT00910000144017_3_Domain_1 (558, 656)

ASHTQRWVVLPLHSTLSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SLGDPRTFPFIEPPPPA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLRDQGALDSSEALTRIGSLL-------------AQLPVDVVI----G
K-MLILGSTFRLAEPVLTIAAALSVQSPFTRSAQ--SNPECAAARRPLESDQGDPFTLFN
IFN--TWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FRDLLEDHG
LLVGTQDLRPGDSYSRLQQRRERQALYQLKRQHE-EGAGRRRKVLRLQEEQDGASSDEDT
D--V---PQEASNSVDIQXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX--------XXXXXXIFHTQTKQGTV---LHPTCVFTNSPEVLHTQEPES
R----ASDGNRXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XX--XXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX--XXXXXXX-----------XXXXX
XXXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPYSLRRLTGLEAQ
NLYVGPQTIPA-APSLPGLFGSSAMSPHPTKGGYTVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLXXXXXXXXXXXXXXXXXXXXXXXXXXA----EEANPEPLQKGVSALQRPYRCE
TCQKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHRAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPRYRINLSVLG--P-AT-RG------SQGLGRHLPAERVAEFHRALLHYLDFGQKHAFG
RLAKLQRERAALPIAQYGNR

PF00270 // ENSGT00910000144017_3_Domain_0 (321, 467)

ILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLSTRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 566)

NISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVF
LSGMAEISTVLKAAQTYASHTQRWV

PF00271 // ENSGT00910000144017_3_Domain_1 (566, 656)

VLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1135)

RQ-FKELLEDHG
LLAGAQAAQVGDSYSRLQQRRERRALHQLKRQHE-EGTGRRRKVLRLQEEQDGGSSDE-D
R--ASPAPPGASDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSHEQLALLKLVLGRGLYP
QLAIPDAFNNS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHTQEL--
--EASSCDGSQDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ARWESALDRQ--------LVHQA
QRRL------------EEE--EQDVPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NMYVGPHTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERITHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHM---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----GRIFPISVIYEPIPKEEAAAAAGKPERLDPRPYLRVLQAIDHKYPPEERGDLLVF
LSGVAEIGAVQEAAQVYA

PF00271 // ENSGT00910000144017_3_Domain_1 (559, 656)

TQTQRWIVLPLHSTLSVSEQDKVFDVPPPGVRKCILXXNAST
NIAETSVTIDGVRFVLDSGKVKEMSYDPQGKLQRLQEFWISRASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
YRXXXXT-DDSFPPYPVPEIQRVALDALVLQVKSM--------GLGDPRTFPFLEPPPSA
SLXXXWTE

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 811)

TAVRYLREQGALDEAEELTPSWXXP-------------RRPPFLHPA----G
K-MLVLGALFGLAEPTLTVAAALSVQSPFLR-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHWAPSKEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRAY
DPRYRINLSVLG--P-DT-RG------SQGLGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLT---------REPS
LPQYEVLIVDEVHERHLHNDFPPGCPPGRLFPSAPDLKVILMSATINISLFSSYFSKHPV
VTGAREACSPITVMYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LMTGAQATQVADSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSEE-D
R--AGPDPPGAGDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEP--
--EASSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ARWEGALDRQ--------LAHQA
QRRL------------EEE--EQDVPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NLYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENSCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPFHCE
ACGRDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHRAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DPGQPKHSI-PALADLPRTY
DPRYRINLSVLG--P-AT-RG------SQGLGRHLPAERVAEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-QRLLPTRPDLKVILMSATINISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGAQAAQVGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSDE-D
R--AGPAPPGASDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEL--
--EASNCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AIRLLAASLRLR--ARWESALDRQ--------LAHQA
QQQL------------EEE--EEDTPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEVQ
NMYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTNDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAALETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHV---------------------------------------
----------

MWWHRELGGGRRVGRWAWKLVNRGSGGGQFPRRSKTLVGLQNKSYLGSQGAQGLEDPGWT
CVCRTDRRRSREVPCVSPVGPGAHCLSSSCATVRSKIGFLKRRWFLLAGTGLALQLRDRV
ATAHHMPPPRTKEGGDD-------RGRHWDPSEEDAPEKWDWNCPETRRLFEDAFFRDED
YIPQGSEERKKFWTFFERLQRFQNLKSTRK--GD-K----DPGRPKHSI-PALADLPRAY
DPRYRINLSVRG--P-DA-RG------SRGLDR-QPPEKVSEFRRALLHYLDFGQKQAFG
RLARLQRERAALPIAQYGTRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVSFESLSQYGSRVGYQIRFESTRTAATKIVFLTVGLLLRQIQREPR
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPERPDLKVILMSATINISLFSSYFGGAPV
VQVP-GRLFPITVVYQPQEA-E--PPASKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQAYAXRTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMGYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------CVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 849)

ILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFHLVEPVLTIAAALSVQSPFTRSAQ--SNPEGAAARRPLDSDHGDPFTLFN
VFN--TWV

ENSGT00910000144017_3_Linker_2_3 (849, 1010)

QVKSERSRSS---RKWCRHRCIEE-HRLY-----EMANVRRQ-FKELLEDHG
LLARAQAPKPGDSYSRLRQRRERRALYQLKRRHE-EGGAHRRKVLRLQEDPGGCSSEE-D
P--------GAGDSVDIQDVKFKLRHSLDQLQAATTSAQD-LTRDQVAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDPFNSS--------RKDSDQIFHTQSKQGTV---PHPTSVFASSPEVLHAQEQ--
--EAGGGEGSRDDKDKLSSRHQLLTFVSLLE-TNKAYLVNCVRIPALQSLL-LFSRSVDT
NGDCSRLVADGWLELQLADSES-AVRLLAASVRLR--ARWESALDRQ--------LARQA
QQRRPE---------VDQEEEEEEDPVARKEVADLSRELLKFTASKVPYSLRRLTGLEVQ
NLYVGPQTITA-MPSLPGLFGSSALSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHVPLTPLERIAHENTCPEAPQDGPPGA----EEAAPEPLQK-ASVLQKPYHCA
VCQKDFLFTPTEVLRHRRQHVLAQIKKIDDAHCWLGCARTETCS-HLEGNSYNLDLAASF
KMQGGCALTQ

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDR-------RDHHWAPSEEEALEKWDWNCPETRRLLEDAFFREED
YIRQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DAGQPKHSI-PALADLPRAY
DPRYRINLSVLG--P-DT-RG------SQGLGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRIL

PF00270 // ENSGT00910000144017_3_Domain_0 (323, 467)

QTLKEHQVV-VVAGDTGCGKSTQVPQYLLTAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 532)

NISLFSSYFSNAPV
VQVP-GRLFPITVVYQPQEA-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLEAVQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 838)

AILYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFT

ENSGT00910000144017_3_Linker_2_3 (838, 889)

LFN
VFN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1137)

RQ-FKELLEDHG
LMTGAQATQVADSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEQDGGSSEE-D
R--AGPDPPGAGDGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLALLKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAQEP--
--EASSCDGSRDDKDKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADGWLELQLADSES-AVRLLAASLRLR--ARWEGALDRQ--------LAHQA
QRRL------------EEE--EQDVPVSPKEVATLSKELLQFTASKIPYSLRRLTGLEAQ
NLYVGPQTIPA-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAAPETLQK-TSVLQRPYHCE
ACGRDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------MVSRARGGAWDR---KLVGPRLC-----VS
LSGHSMAPPRPREGRGH-------RDHRWAPSEEEALEKWDWDCPETRRRFEDAFFRDED
YIRQGSEDCHKFWAFFERLQRFQTLKTSKK--EE-T----DPGHPKHCV-PALADLPRPY
DSRYRINLSVLG--P-DM-RD------IRGSGSQLPPKRVSEFRRALLHYLDFSQKQAFT
RLAKLQRDRAALPIAQYRKCIL

PF00270 // ENSGT00910000144017_3_Domain_0 (323, 467)

QTLKQHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYKVLIVDEVHERQLHNDFLLGVL-QHLLPTRPDLKVVLMSATI

ENSGT00910000144017_3_Linker_0_1 (467, 531)

NIMLFSSYFGNAPV
VQVP-GRLFPITVIYQPQEA-E--QTASKSERLDPRPFLRVLEAIDNKYP

PF00271 // ENSGT00910000144017_3_Domain_1 (531, 656)

AEERGDLLVF
LSGMAEIGAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 730)

GPGVC
YRLYAESDYDAFTPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----T

PF04408 // ENSGT00910000144017_3_Domain_2 (730, 842)

AIQYLQEQGALDASEALTPIGCLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFPRSAQ--SSLECAAARQPLDSDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 891)

FN--AWVQVKAERSQNS---RKWCRRRGVEE-HRLY-----EMANLRRQ

PF07717 // ENSGT00910000144017_3_Domain_3 (891, 1137)

-FKDLLEDHG
LLAGAEAATPGDSYSRLQQRRERRALHQLKRQHE-EGAGRRRKVLRLQEEAEDGSSDE-D
H--AGPAARHAEDSVDIQDVKFKLRHNLEQLQAAASSAQA-LSREQLVLLKLVLARGLYP
QLAVPDPFNSG--------RKDSDQIFHTQAKQGAV---LHPTSVFASSPELLHVQEP--
--QATCGGGSRDDKDKMSSKHQLLTFVSLLE-TNKLYLVNCVRVPALQSLL-LFSRSLDT
NGDCSRLVADSWLELQVVDSEG-AVQLLAAALRLR--ACWESALDRQ--------LSHQA
RWRRREQQQRRQRLGEEDEDEEEAESVSRAEVAALSRELLQFMATKVPYSLRRLTGLEAQ
NLYVGPQTVTA-TPKLPGLFGSSALSPHPTKGGYRVTNFLTYNCLLSDTDLYSDCLRTFW
TCPRCDLHLPLTPLERMAHESACATDL-HGGPGA----EEATTEQSRK-PSALQRPYHCD
SCQKDFLFTPTEALRHRRQHM---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREGRDC-------RDHPRAPREEEALEKWDWSCPETRRLLEDAFFSEED
YICQGSEECQKFWTFFERLQRFQNLKTSRK--EE-K----DSRHPKHSI-PALADLPRTY
DPRYRINLSVLG--P-DA-WG------SRELGRHLPAERVSEFRRALLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-QRLLPKRPDLKVILMSATINISLFSSYFGNAPV
VQVP-GRLFPITVVYQPQEV-E--PTTSKSEKLDPRPFLRVLESIDHKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDAQAHLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 731)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TA

PF04408 // ENSGT00910000144017_3_Domain_2 (731, 842)

ILYLRDQGALDSTEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SSPECAAARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 1010)

FN--AWVQVKSERSRNS---RKWCRRRGIEE-HRLY-----EMANLRRQ-FKELLEDHG
LLAGAQAIQAGDSYSRLQQRRERRALHQLKRQHE-EGAGCRRKVLRLQEEQDGGSSDE-D
R--GGPAPPGAGNGVDIQDVKFKLRHDLAQLQAAASSAQD-LSREQLAL

PF07717 // ENSGT00910000144017_3_Domain_3 (1010, 1137)

LKLVLGRGLYP
QLAVPDAFNSS--------RKDSDQIFHTQAKQGAV---LHPTCVFAGSPEVLHAREL--
--EASSCDGSRGD-QKMSSKHQLLSFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCTRLVADSWLELQLADGES-AVRLLVASLRLR--ARWESALDRQ--------LAHQA
QQRL------------EEEE-EEEEPVSPKEVAALSKELLQFTASKLPYSLRRLTGLEAQ
NLYVGPQTIPV-TPHLPGLFGSSTLSPHPTKGGYAVTDFLTYNCLTSDTDLYSDCLRTFW
TCPHCGLHAPLTPLERIAHENTCPQAPQDGPPGA----EEAVPETLQK-TSVLQRPYHCE
ACGKDFLFTPTEVLRHRKQHV---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTREERDRGDRDRGDRHHHRAPREEEALEKWDWKCPETRRLLEDVFFRDED
YIRRGSEECQKFWAFFERLQRFQHLKASRK--EE-K----DPGHPKHGI-PALADLPRTY
DPRYRINLSILG--P-DT-RG------RQGPGRWLPPEKVSEFRRALLHYLDFEQKQAFG
RLAKLQRERAALPIAQYGNRILQTLKEHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATRIVFLTVGLLLRQIQREPG
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPRRPDLKVILMSATINISLFSSYFSHAPV
VQVP-GRLFPITVVYQPQEA-E--QTASKSEKLDPRPFLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISTVLDAAQAYASLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 732)

GPGVC
YRLYAESDYDALAPYPVPEIRRVALDSLVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAI

PF04408 // ENSGT00910000144017_3_Domain_2 (732, 821)

LYLRDQGALDSSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLAEPVLTIAAALSVQSPFTRSAQ--SSLD

ENSGT00910000144017_3_Linker_2_3 (821, 891)

CATARRPLESDQGDPFTLFN
VFN--AWVQVKSERSGNS---RKWCRRRGVEE-HRLY-----EMANLRRQ

PF07717 // ENSGT00910000144017_3_Domain_3 (891, 1138)

-FKELLEDHG
LLSGAQVAAPADSYSRLQWRRERRALHQLKRQHEEEGGGRRRKVLRLQE--DGCSSD-ED
R---EGSASQRADSVDIQDVKFKLRHNLDQLQAAASSAQD-LTRDQLALLKLVLGRGLYP
QLAVPDAFNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFASSPEVLHTQEQEA
---SGREGRSQDGKDQMSCKHQLLAFVSLLE-TNKPYLVNCIRIPALQSLL-LFSRSIDT
NGDCSRLVADSWLELQLADSES-AVRLLATSLRLR--ARWESALDRQ--------LAHQA
RGRQRL----------EQEEEVESPAVGPQEVAALSRELLQFMAAKVPYSLRRLTGLEAQ
NLYVGPQTITA-APSLPGLFGNSTLSPHPTKGGYAVSDFLTYNCLTSDTDLYSDCLRSFW
TCPHCGLHMPFTPLERIAHENTCPEAPRDGP-GS----EEAAPAPPQK-TSALQRPYHCP
VCGEDFLFTPTEVLRHRRQHL---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPSTREGRDG--------RDHRTPREEEAPKRWDWSCADTRCLFEDVFFREED
YIHRGSEECQKFWAFFERLQRFQHHKGARK--EE-K----APGRPSPAA-PGLADLPHTY
DPRYRINLSIVG--P-GP-RG------CQGLGRRLPPERVSEFRRAMLHYLDFGQKQAFG
RLAKLQRERAALPIAQYGTRILQTLREHQVV-VVAGDTGCGKSTQVPQYLLAAGFSHVAC
TQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATRIVFLTVGLLLRQIQREPS
LPQYEVLIVDEVHERHLHNDFLLGVL-RRLLPKRPDLKVILMSATINISLFSSYFSHAPV
VQVP-GRLFPITVVYQPQEA-E--ATTSKSEKLDPRPYLRVLEAIDNKYPP

PF00271 // ENSGT00910000144017_3_Domain_1 (532, 656)

EERGDLLVF
LSGMAEISAVLDAAQAYASLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 732)

GPGVC
YRLYAESDYNAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----TAI

PF04408 // ENSGT00910000144017_3_Domain_2 (732, 842)

LYLRDQGALDTSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGSMFSLEEPVLTIAAALSVQSPFTRSAQ--NNLDCATARRPLESDQGDPFTLFN
V

ENSGT00910000144017_3_Linker_2_3 (842, 889)

FN--AWVQVKSERSRNS---RKWCRHRGVEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1137)

RQ-FKELLGDHG
LLRGAQAVTPGDSYSRLQQRRERQALHQLKRQHE-EGGGRRRKVLRLQE--DGCSSDEDH
E---GSASRATHDSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLALLKLVLGRGLYP
QLAVPDAFNSG--------RKDSDQIFHTQAKQGTV---LHPTCVFANNPEVLHTQQQEA
---SGHEG-SQDDKDKMSCKHQLLAFVSLLE-TNKPYLVNCVRIPALQSLL-LFSRSLDT
NGDCSRLVADSWLELQLLDSES-AVRLLATSLRLR--AQWESALDRQ--------LAHQA
QRQR-L-----------EEEGEESPAVSHQEVAALSRELLQFMAAKVPYSIRRLTGLEAQ
NLYMGPQTVTT-APSLPGLFGNCALSPHPTKGGYIVTDFLTYNCLTNDTDLYSDCLRSFW
TCPYCGLHMPFTPLERIAHENTCPEAPRDQASGV----VEAVPAPLQK-TSALQRPYHCE
TCGEDFLFTPTEVLRHRRKHL---------------------------------------
----------

------------------------------------------------------------
------------------------------------------------------------
-----MPPPRTRDSRHHDRDHRDRSHRAAREEEEEARERWDWNRPETRRLFEEAFFREED
SIRQSSEERHKFWAFFERLQRFQNIKASRKEEEEEK----GPGLAKPPI-PALADLPRTY
DPRYRINLSVLGPDVWGS-RG------SDRPDRRLPPDKVAEFRKALLHFLDFGQKQAFG
RLAKLQRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPG
LPQYQVLIVDEVHERHLHNDFLLGVL-RRLLPARPDLKVILMSATINISLFSSYFSGAPV
VQVP-GRLFPITXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00271 // ENSGT00910000144017_3_Domain_1 (569, 656)

XXXXXXXXXXXXVFDVAPPGVRKCILS----T
NIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRT

ENSGT00910000144017_3_Linker_1_2 (656, 729)

GPGVC
FRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSM--------SVGDPRTFPFIEPPPPA
SLE-----

PF04408 // ENSGT00910000144017_3_Domain_2 (729, 839)

TAILYLQDQGALDGSEALTPIGSLL-------------AQLPVDVVI----G
K-MLILGCVFRLAEPVLTVAAALSVQSPFTRSAQ--GSPECAAARRPLESDQGDPFTL

ENSGT00910000144017_3_Linker_2_3 (839, 889)

FN
VFN--AWVQVKSERSSNS---RKWCRRRGIEE-HRLY-----EMANLR

PF07717 // ENSGT00910000144017_3_Domain_3 (889, 1157)

RQ-FKELLEDHG
LLAGVQAATPRDSHSRLQQRRERQALYQLKRQHE-EAGGRRRKVLRLQGEADGGSSDE-D
A--EGTATREAGDSVDIQDVKFKLRHNLEQLQAAASSAQD-LTRDQLSLLKLVLGRGLYP
QLAIPDPFNSG--------RKDSDQIFHTQAKQGAV---VHPTCVFANSPEVLHVQEPEA
R----DKEGSRXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXSLLLFSRSLDT
NGDCSRLVADGWLQLQLVDSES-AVRLLAAALRLR--ARWENALDRQ--------LARQA
WRRRDH----------RDEEEEEEVAASPKDVVALSGELLQFMASKVSYSLRRLTGLETQ
NLYVGPQTITT-APSLPGLFGSSSLSPHPTKGGYIVTDFLTYNCLTSDSDLYSDCLRTFW
TCPHCGLHMPLTPLERMAHENNWLQAPPDGPP----------------------------
------------------------------------------------------------
----------