Query Results 

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--------------------------------------------------------MVPE
ERRVGLSSDETSSDALKSW-HSIYVL-DSKEQPLACQQKQRQLVKPVTESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRKETRSQLDYEVLREKAFQKSSTSFSPETSVLDSQVMTALKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGMHRLQNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQKALAKEKYKALRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRTGQGSIYLQKVQRKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITS
FVANILQAARQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSADL
KPSSDSLYSE--EEDEEEDSKTEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVRGYRLRGQYFPRNYKQLEEDLDNNPQIQQALHIQQVLLEGVLCEVQEFCREHHWITGI
YEFLQSWGPQKLEDMRGGPIKNYVMLVSRLNIWQARVSSMPIELLTEGKLLLLSCHDVQA
EMESKLDSIRKDILAQVQNECWSLSQQLMTELTDFMHIFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYIRALHELIRNHFSLFSAENEALDISVRRQFGESPILPHPPPPQPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHDIMPKLQQLMAAALAELEGLLAKALSGPF
MDPTQDQRSTEHQLVSLERQFQNTVSDLNELHHAYVIFTEDETPVPLPICGTHPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTEGWLTEAARMSTTLGLHSPVLQHCMRIL
GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFARSNQP
GGVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQ---VLHRPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQALSKILAIQKSGDLNKIALEWVAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMSISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVSFKSCPTG-EKNTDDWES----SPNTQTQMEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEETLLEWGTLAMVSMH
MRKLEVLVNFMQAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTAS-SEPSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRATVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTID
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIQTLNV
TKEEPKCQKPRSLAATEEAALLHALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEP
MTYKLMKPLVVEELQQVGLHPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGRKRQTEESMGTQHWIICDGASNAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADTTGMSPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNHMA
EVLVPATLRFLTRQGVSSLLQVH-GQRAVCAGVAEVTSMARILHSLLDPHLRLKEEKAP-
--GPEDLSCSDPVAQ---SFRSSKSSFL-NQSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2783)

QTERLLYVVDLLLSGGQPVLLAGEAATGKSAFV
EVLVEPHHPYMCSPIHPAFSSTHLRLLLSRGIQGQTEA-SPQPGHHQDSKGSLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNC
FMPSPLHPHYRFSLHSVSHLLSSLQLLPNRTGSRGFMDYPNHQEHLRLVSGLRGTCLTVM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQEDE
E---EEERVS--PE--------------------------------------SQTPVIPS
LTPSI---G--PVSRGARESISH--KIRQEKGTRASNYRLQVRRSFKTWWQKKPQ-MDLV
SPL--LLPVLLLHPQEKPSDLVFSQELILGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPS
-GSEEAILQCLQDASWHAGMLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
HIGEHL-PRENLGIKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-QSLPLDDGSWKYPDLQASVPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLI
KEHGTHANLIFNLEQQLKDSCKS------------LSMFQQQLEQSKLLYKQQLEEC

PF12777 // ENSGT00910000144015_1_Domain_7 (3418, 3687)

RHQ
ENLIENLAKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKRLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMNDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLTREQARLGYYQFQAQETLEHNL
ALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPMHAWTTQLQKLKGRCMTVFG
DTLLCSAAIIYLGPFPPLRRQELLDKWLALCWGFQ---EALGPDDVAQALKRKQKSVSIP
-PKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALIWLDPLPLEENRSFAPAPTEGRGKGLM----RNQNRESK-TDMKEEDDESED
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
RPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMEVLEEQMLHEILC
RECPELETRWQDLKIRTLDTCKAVKAAEERLLTMLLFQ--NPKHQKPAKFLRNMVRAQGK
LCQLRAHFEELEGQKLREMVSWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVSGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSSAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLQPECLAGALADFTTSL
LGRPLDENMCTPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQ--GQKQ
LQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHFMPVFWNQSLE
LGHVLIDSVELAQQVPYMQP-PTQALPLLLLHGLLLYRQLYGTRLQAHRGRWSQGTLTQV
LQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHT
PQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGAQAWLLRRQSRALLSA
LQRSSPVWVPESRRGA---QLAERRLRQRLVQVNRRLESLQDLLTHVVRQDKS---GAPW
SVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADPSSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGSVSS-----QIQYKHLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWNPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPPP
ANLTVYSCPVYMGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

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------------------------------------QRRQRQFLKALTQSL--PGLRRLV
TELRTLFSAVLQDGSLEAWHYLHAVLCLLPPYQALLVGHLDLLPFLEQLYRWAPWVQTQL
QLDLLDAIDQAFPRDTSLVESASHVDCCLQKQRFRQGPPIPACPFVRARRSGQQGEEKLA
TWLRPLTLPELQHSLGIVGAEVAMNEAPWRDGLGLLSLALAADIPVQYESGGTDDMEEEP
VGRKKTMSQLDSEVS-EKTFKKSSTGGLPPTSRLSSQAMAILKTERYLKKIHFVYLNVAP
SRHFRPYSLVVVPPNKVNPEHYIFSPFGVLHVHPKEATETMTLGTWHRHFVLWQHLQLIP
FFKYCLLRKAWACWRKTVKFQRLHRCRDFLGRHLLFAVPHFGVALLHISRLLQELHSVSW
LPQEPDRCYELLDLQRALTQENHKALELLSRCLQLCKSILDMVQEDTYQMQQGLQERVKN
CQRVGTDQSSIYLRKVQCQQLEQKLKRVETWLLQLGQLARLVHYMICQSLVSIIEEKITS
FVANILKAPRQNPFLSAQLVFDRHGQLSHEPCIEDIIQILTGGLQHVKVSALKVMKSTDL
KTSEDSLN--SEEKGEEEGSNTEILMPKSQ---DDVVQIFCGPNVGLVWPWKSHTITQAL
EVRGYRLRSQCLPPNYKQLQEDLNNNPRIQQALAIQQALLVDMLWEVQEFCRDHHWMTDM
YKFLQAWGPQKLESMRGCPISNYQTLVSHLDGWQAGVSQMPIELITKGKLLLLSCRDIQA
DLESKLGSIRKEILKHVQGESWSRSQQLMKELTDFIEAFQIINSDIHTIARCSQKLNKAH
EQYSELEERTEYIRALHELIRKHFSLFSADTEALDISVRRQPREPPPP-GPPPSQARGPD
CPLPAPQLLDLWEAFQFERSQASEFLLSKRHVIVPKLQQLMAAALAELDGLIGKALSSPY
LDPAQEQKSMENQLIALGQQFQDTTSYLSELHHAYTTFTGDESPVPLPICGIH

PF08393 // ENSGT00910000144015_1_Domain_1 (1134, 1605)

PILHQQS
IWHLYRVISENISDWKCMAFAKFSLPMAQEKIEGWLTEVARLNATMGLHNPVLQYCIHIL
EEFHIYLPLLTKLSSLQLHGLNFQVLLRALGLGSL-NVELLTLGQLLTCPLLDFADQ--I
NQIWRNENEHNHAQEALQQLRQVWEARKLRLLNFILHVPCKPSTLGRSKKQ---MLHR--
-DVMAQDSGTFILSDYSSLQDSIQESLQVLFKILAIQKSGDLHKRALEWMTILHDLS---
DILAVWVTFQQKWIFLNKILHEMKIQFPSSDLNSRFKAVDDQYRTLMQNSVADPLVLSLV
-VPGAQRNTSFQGQKLQQMLQAGSVELEGIITALKSVLYEFCVHFPRLFFLSDSELVDLL
VARLEPDEAQIWVRRCFPHVLAVSFQASLTG-EH-TDAPES----KPSLQTQVEGFAVLG
AGGEKVKLQPPLLLHSDLPRWLTSLEKVLRVALVHRLQGCVAARLQRSVALTPSL--DKE
LPQQSQLS----SQLYAHNWLDLVKAFPWQCVLVAEEVVWRAEMEEALLEGQTLTMVRKH
VCKLEVLVHFVRTQKACQVGHPLPSVRETSLLSALVAMAVTHRDIAQLLKEHKVSDLTDF
HWARQLKYHLGSSHIISKSPLQSLKTIAS-TDTYLSPAACWIDVLGRSFLYNYEYLGPRL
GSLPSLLPEWPALALLLALEEVACGTLLGPNGMGKAAMVKSLAQALGRQLVIMPCLPQIA
APSLSNYLNGALQGGAWLLLEAAQHLPLGLLSALGQRLAELHRLYVPLYRQVSRSTSTID
-------PTHPQILGRGFFERHHVDMRLGYGCLLTLRSLSPAVPANLRLLLRPVALTL-P
NLQQLAELTLLGAGMREASLLATRLSKFFSLERELVSGPLPCRLPLFKWVLADTIQALNV
AKEDPTSQLSLGLAAAQERALLRALLRSPLFSILDGPRLHHLQELLCGIFPRARQVLAEP
VAHRLRKPLLVEELQQAGLHPSTDILGSLEQLSQALGHTSGILLLGPAGSGKTTCWHSLF
TIQNRLAAMEDT----STQGRLPVEITHLYPSVLSPEEFLGWQEGPCWHQGILPRLLRAT
SQCKAVDPKSKAQGSVGTQHWIICDGVSSAAWLDAVTCLLRDPPQLILPCGQQIERPPDT
FLLMEVGDATGMPPAVVGRCALVWCGGEQTWKGMLRALMTTLPQEYCLQPHTVTELNHLA
EVLVPATFQFLTRQGASSVLQAH-GQKAVCPGVAEITSLARLLRCLLDLHLRIDEETHVP
--GEEDLSHSDSGTP---SFKSLKSSSP-TRSQADSSDVLNKRREHLLVVNSFLFALIWG
FGAH--------------LPS-RL-WPAFDTFLRDSTSYLPNYPEPSPSASVFDLHLCPE
DGTLVPFTGQYVGSRIKGSLGTFSPSPQTERLLYVVDLLLTEGHPVLLAGEAATGKSAFV
EVLVEPHHPYIYTPIHPAFRTTHLRLLLSQGVQGQAQA-SPRSGQPLNSKGSLLFLLEDL
HLAASDPEKSCQPVLETLRQAMNGTVCAHSTLELQRLQPIVNFLATATVPGFCECPLCPR
LFRLFTVLALADMTQAMLLSRHTPIIQTWLERFPCVEREGVLARALICASMEAWEIVGSC
FLPSPLHPHYHFSLHSVSQLLGSLQLVSTRTGSRGFLDYPNHQEHLRRVSGLRGTRLLTM
MAMRNIVRLWLHEAQRTFCDRLDSPRERDYCAKLLLEVAQSVFCCGPAPQSLDKGYKEKE
E----LEEEERVPEVESEGELDQWEDL-----SNSGSDTE-EEDTYDLWVTTGPPSSDSG
HASSI---A--PVERESTENISQ--KINQEEGTRASSYKLQIKR-SKNSWQKTSQ-SDLD
SPL--LLPVLLLCPQEKPSDLIFSQELILGSNSESPN-MYLERQWESLKEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRCTAIILAANICQARIFYLPC
-QPEKAILQCLWDASWHAGMLGQPVALLVPNDVDLTTLHRLLALARSGSFPDQYTEAHLE
NIEEHL-LRDA---KQTNKKEMLLQRFYQQVCSHLHM-FILIGE--DQAHKQLPSTLFRR
LLQLAITSIDHYEPWDQDSLISVAQHHLDSA-QNLPLGDDTLKHPDLQASIPSVAKAMAF
IHLSAASYHGHLCPELPLVTPKTFLDFLETFMLLQQQMILQMKNKAQRFNNALGNLTTIF
EQHNIHITQVSILKQEMRASYKK------------LSILRHHLEHSKILHKRQLAECRQQ
ESLIKNLTKQWDALRAQHEAFLEQMGKAFLGPLSQLKVTDFEELRSYRAPPESVVQVTNA
LCDLFHRERGWASAKQLLSTEDFYQELVFFPKEKMTDSEIINLSIALKAPGMSDAALRAV
STPAASLAAWLWAVLRYRLAQHRGLPTGLLLRQVEATLAREQAQLAHYQFQSKEILERNL
ALTTQLEGIQTSHGHLVENLNWSQSDQYHTWPIKAALLAPMHSWTAELQKLKRQCMTVYG
DALLCSAAIVYLGPFPPLRRQELLAKWLAVCKGFQ---ETLGPDDVAQALKQNQKSVITP
-PKTPLLSTCSPFSLLSLLSSESEQFQWDRDLKPRAKSARLAGLLLRSYTHYFSCRWPLV
LDPSKQALKWLNPLPLEHTRCMAPVPTKGRGKKKG----LGKGDRSQEKEDKEDEE-EE-
-DNNSEK----SPEAEEQKAEEKG------KEEVVDEEEKQEQENKEGETERQESRPASE
TQSPSFPYLIVLSGSDPDL--GPQLLEAAAKGLPVLLTNVE--LGLGCQELPFLLQREQL
SPPQVQPGFCLYLSTTQPLGALKK----VLGCELLKVLNVLDLGLNMDILEEQMLHEILC
RECPKIESRWQNLQMRSLNTLEAVEATEEQLLMRLLSK--NPTKQKLAKFLRDMVRNQAE
LCQLHAYREELEDLRLQEMVQWVPYQHVARHGIAIIRALSPLQDLLPPFRMSPENWLAAT
KRALNSMKQCENHPGKDLPSHLLQLKTQLTRQLLGSTVAALGLAHMPLVGALGALALLCE
VRKAPHLERLALWPGLEASPSTGSSK

PF03028 // ENSGT00910000144015_1_Domain_9 (4227, 5031)

PVPGVARPAWLGQRAWHECGMLELLPPFAGLRVS
LAGHSSVWQSYLSLSSTVLGPIPG--SGPNLLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENLSPSTIPFEQSQATQPLLVLLPPPGHPTATLHPLAVIQKLAAQHEQ--GQKH
LEVIALGSEAWNPVSAVVSTLGQAMIFL-----------------GPFPTLGPKLELAGL
TTIFSDPELELLLAPSASRN--MVHKDFRLWLIVPAESIASLPAVLTQHCMPVFWEQSLD
LGHVLLDNVELAQQELYVQP-LTRKLPLLLLHGLLLHRQLYGMKLQAHRGHWNQVTLTQV
LQMQDQLWASLSNPRAAMEELAASVFYGGPLGDNKDREALISLIHACLSPSRGSWDQPHT
PQYLLATLIPSPDLEELDAMSECKAQMHQLPTPTEPRTCGLSAGHQAWLLRRQSRALLRA
LQQCSLTWVPAPDGSRHTEKQRQRRLRQRLVLAKQTLESLQALLTQTTCQDESGASGAGW
LDMGYDAGRAVEGFLQMEVWELSQLVSTLQGDLNCLLQQLEGAPPCVSQRCVAVAHALWT
GRLPLPWRRYAPAWLQPPWHWLRQLSRRGQLLVRYLGAG----TAAPKRIFHLSAFRHPH
RLLLSLRWEAAFAMVPIDHHVPSLNAPDGQDLSSR-----H-LHKRQELNSNPLHLQVVS
SPKPTVPETGAVLLIGLQLWNAQWDPLAGALKDGPTSQPSPLPPVSVSTQARDTNDLPPT
AGLAVYSCPVYMEGPLGTARLHSKNILMYLPLPTKLSPAICVQRRVHVCSPPLS

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----------------FEKSQASEFLLSKQHSIVPKLQQLIAAALADLEGLIEKALSGPF
MDPTQDQRSTERQLIALERQFQNIVIHVTELHHAYATFTGDEKPVPFPVCGTRP

PF08393 // ENSGT00910000144015_1_Domain_0 (1135, 1293)

IVQQQR
IWHLYRVISENISEWKCMAFAKFSLSMAQAKTEGWLTEAARMRTSLGLHSPVLQRCMRIL
EEFRSCLPLLTKLGSLQLQNVNCQSLLLALGLGSLHNIELLTLGQLLACPLLEFADR--I
NQVWHSENERIHAQDTLRKLQRHWEVRQLRLL

ENSGT00910000144015_1_Linker_0_1 (1293, 1326)

NFILHVPYEPQAPERSKRH---MVRF-L
GEVVG

PF08393 // ENSGT00910000144015_1_Domain_1 (1326, 1603)

KDSGTFILSDYNSLQDSIQESLQVLFKIVAIQKSGDLYKTALEWVTIMHGLD---
AVLEVWVTFQQKWIFVNKVLYEMKIQFPSADLNARFRAMDNQYRTLMRISVADPMVLSLV
-VPNAQRSPYFQGQQLQQLLQAGSVELEGIIMALESVLYGVCAHFPRLFFLSDSELVALL
AAAPESYQAQLWVRRCFPHVHAVTFQSCPVD-EKDMDES------STSKQTQVEALAVLG
AGGEELKLQEPLPLYPDFPKWLSSLEKSLCLALVHMLQNCVAARLAQGPFLVEAVRQ---
FPQKTQVA----LQLYVYNWLELVKVFPWQCVLVAEEVVWRAEVEEVLLKGGSPAMVSRH
THKLEALVYSLRAQRVSQGGQPLSSVRQASLLSALLVMAMTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHMIPQSPLQSLKTIAS-TDPSLSPAACWVDVLGRSFLYNYEYLGPRL
GTLPSLLPERPALVLLLALEEVACGTLLGPRGVGKTAIVNNLAWALGRQLVTMPCSPQLQ
AQCLSNYLNGALQGGAWLLLEAAQHLPSGVLSALGQRLAELHYLYAPLYQEASQTTSTVD
-------PTQPQILGSGFFEKHQVSMRLGYGCLLTLSSLSHAVPANLHLLLRPVALAL-P
DLQRVAELTLLGAGIRDATRMAARLSKFFFLEHELVSRPLPCRLPMLKQILEDTIQTLNE
TNREPKSQQPRSQATIEEAALLRALLRSPLFSVLSGLHLHNLRELLCGLFPSASQALEEP
MTQRLLKSVMVEELRQVGLHPSSEILGALEQLSQALCRASGILLLGPAGSGKTTCWHSLF
KIHNRLAAMEDA----STHGCQPVEITHLYPTALSPQEFLGWPEGPCWHHGVFPRVLRTS
RHCNNENPKQQTEKSVVIQHWIICDGATNAAWLDSVACLLSDLPQLSLPNGQQIARPPGT
FLLMEMADATGMSPTVVGCCALVWCGGEQTWQNMLNVLMASLRHEYRLQPETVTELNLLA
EVLVPAIFRFLARESASSVLQVH-GHQAVCLGVAEVTSLARILRGLLDPHLRLEEEKAH-
--GPED--FNDPVAH---SVKSSKSSSL-SQSQVESDDTANKRREHLLVVSSFLFSLIWS
FGGH--------------LPS-RL-WPLFDTFMRSSIAFLSNFPELPSSALVFDLHVNPE
DGTLVAFTEQHLSNHVKGSMGIFYPSIQTERLLHVVDLLLSGGQPVLLAGEAATGKSAFV
EVLVEPSHPYIHRSIHPAFNSTHLRLLLSRGVQGQDED-SLLPGHRQDSKGSLLFLLEDL
HLASSDPEKSCQPVLETLRQAIDGTVYAHSTLELQTLQPIVNFLATATVPGYCERSLCPR
LFRLFTVLVLESMTQATLLSRHVPSTQAWLERFHSVERENVLARALVQASVEAWEAVSNC
FMPSPLCPHYRYSMHSVSNLLGSLQLLPSRVGARGFVDCPNHQEHLRRVSGLRGTRLAIM
VAMRNMVRLWLHEAQRTFCDRLNSPRERSYCAELLLEVAQSVFCCEPKSQHVCKELEEDE
-------EEERVPEVESEGELAHWEDL-----SNSDSDTEEESLQL----------RDPS
LPSFI---S--SVSKESLESISY--KVRQEEGTRAYKDQLQ----EKNWCQKTTQ-MDQV
TPL--LLPVLLLRPQEKPSDLVFSQDLILSSNSDSPN-LYMERQWESLEEQLATSAAQLR
LSPHLARCHSMAQHVARLVRVLSRPRQHGLLLTGTLGTGRHTAIILASGICQARMFLLPV
-GPEKDILQCLQDASWHTGILNQPAALVVPQNVDLTTLHRLLALATSGSFPDQYTEADLE
NIEEHL-PREHISAKPNTRRETVVQRFYQQVCGHLHM-FFLIGD--EQARKELPLTLFLR
LLQLATACIDRYEPWDQTSLIKVAQHQLEGA-QRLPLDDDSWKFPDLQTSIPNVAKAMAH
IHLLAASYHEHLCPALPLATPKTFLEFLNTFLLLQQEMILQMKNKSQRIQNAMENLEKLI
EKHNAHANMVSTWEQKLVNALKN------------LSTYQQQLEESRLQYKRQLSDCRHQ
ENLIENLVRQRDALKDQHEAFLEQMGKAFMGPLSQLQVADFEEIRSYRAPPESVVRVTNA
LCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKMTDSELIKLHQALKAPGMSDAALKAV
SVSAANLAAWLWAVLRYGLAQRRGLPTGLLVQQVEATLSREQTRLGYYQFQAQETLERNL
ALIKKVEEAQASYISVLRSLSLSQSIQYPKWPIKAALLTPMHSWTTELQKLKGRCLTVFG
DALLCSAAITYLGPFPPLRRQELLDKWLALCRGFQ---EASGPDDVAQALKQKQKLVNMP
PPKKPLLPICTPFNILSLMSSVSEQHQWDQDQKPQAKSARLAAVLLKSTMHYTSFSWLLL
LDPSNQALGWLNTL--EENRSLTSV---GRGKGKWKDVKRHKNRKSKEEDLKEEESECS-
-----DETEEEEAEERENEEEK--------------EEEEEEEKEEKEEMESQETKSSSE
TQTSSLPCLRVLSGADPEL--GPQLQEAAAVGLPVLLTNME--LGLGCQELQWLLKREQL
SPPQVQPGFYLYLSTTLPLHALEK----VLGCELLKRLNVLDLGLNMEILEEQMLHKILS
KERPELKSRWEDLKIRALDTCKAVEAAEEQMLIRLLPQ--NLKGQKPAKFLRNMVRSQAE
ICQLRAQWEELEGQKLQEMILWAPYRRVAWHGMAIVKALTPLQNILPLFRMSPENWLAAT
DKALDSVKPCEINHGEDLASHLLQLRTHLTRQLLGSTVAALGLTQVPLVGALGALAVLQV
TRKASELERLALSPGLTASPSTSHTKPGSSMARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 4993)

AWIGPKAWYECRVLELLPPFMGLCSS
LAGHSSVWQAYLSLSSTVLGPAPG--PGSEPLSLLQKLILWRVLRPERLASALADFTTSL
LGRPLDENLSAPTMPFQHSQATQPMLILLPPHGHPTAAVHPLTVIQKLAANHEQ--GQKH
LQVIALGSEAWDPISVVVSTLCQAMDKGYWLVLDNCHLMP----HWPKELLQPLLELLDG
AKVVSDPELELLLTESENRNVATVHRDFRLWLIASAESSASLPAVLTQHSMPVFWNQSLE
LNHVLIDSVELAQQGLYMQP-PTQMLPLLLLHGLLLHRQLYGMRVQAHRGRWNQGTLTQV
LQNQNQLWASLSNPSVAMQELAALVFYGGPVGDSEDRKTLVSLTQACLNPSSRGGVQTHT
PQYLLAMLMPSPELGVLDAMAECKAQMHLTPTLSDPRICGLSESSQAWLLRRQSRALWKA
LQLSSPTWVPVAQGHA---RRRERRLQQRLLQAKRKLELLQVLLTNAA-QHEF---SAPW
TVLSPNARRPLEGFLEVEVLELTQLVGIVQSDLDCLLQQLKGAPPCASQRCAAVAHGLWT
GRLPQPWQSHATAGQQPPWHWLRQLSRRGQLLVRYLGTGMD--TSVAERIFHLSAFCHPR
RLLLALRWEAALNQ-----NVPSSIR--SPGMGSS-----QFSHKRQELNSSPLHLQVEN
GPNATVPEMGL-LLIGLQLLNAEWDPIAGALQDSPSGQPSPLPPVSVSIKASDARDLPSP
AGLTMYSCPVYMAGPLGTTKLQSRNILMHLPLPTKLSLATCVQRRIHVCSPPLP

------------------------------------------------------------
---MKPHSQTS-PPSLPMPSTSCGSGQTQKPKAWNWHLDPELWARSVRQQLNTCLRFILE
EKK------TPWFYTLQSG-LPGCSC-SGQEHSWDCQMKQ-ENLKAVVESEQRTLLKLLL
SELQSLFSAVMQDGSCEAWRYLHAVLGLLPPYREMLAGQLELLPFLEQLYSWAPKVQAWL
KLDLLDAIDKAFPPDSSLLHSSSHVDCGPWMKRFHRGPPCSACPFVKAQWDQQQK-KELA
TWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLPLALATDIPVQYESSDIEHAEGEP
DGR---KPQLASEAPEEKALKKKS----SRTPVLRSQVKSLLERDWSQKKIHFLYLNVVS
DRHFNPYKLVVVPPDKVNPEHYIFSPFGILHIHPVEGSEAMTLGTWHRDYALWRELQRIP
FFKNCLLRKALTCWKKSVRLHGLHRIQTFLKTHLLLAIPHFGAGMLHISRLLQEFRSVSW
LPKEPDRCYELVDLQKAIAKENHKALRVLCHFLNLCTSILQLIHEDTYQMQQGLQERVQN
WNRIRKGQGSIYLQRTLCRHLEKKLKQAETWSLKLGKFARLIDYMICQNLVSILEDEISS
FIANTLQAPRQNPFLLSQLVFDDNGQLSPMPRVESIIQDLIKSLQAIKTSALKVLQSTDL
RTSRDLLYSE---DNKDQDSNAEFLMPKFHGKASDAVHLFCGPNVGYVWPWKSHAITDVL
EVRGHRLRGQFLHPNYDHVQEDLDKNPGIQQALAVQQALLEDMRQEVQEFCNKHKWVEVI
YEFLKAWNSQKLEDLRGSPINDYVNLVIQLKKWQERVSNMPVELLTKGKLLLLSGRDVQE
ELGTKLNNLRKNILEQAQNECWSRNQQLMTELTEFLRVFQTISSDIHAIAQCSQKLNEAN
EQYCQLEERVEYVRSLHDLIRNHYSLFIAENETLDIA-----------------------
-------LLDLWEAFQFERSQVSEFLLSKQHAIVPRLQQLMAAALAELEGLLGKALSGPF
MDPSQEQRSTEQQLGALEHQFLNILNNFNALCNAYCTFTGHKKPMSPPASGNRLIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

LQQR
IWRLYRIISENLGEWKCMAFSKFNLSMAREKTDAWLTEAARLGTALGQQSPVLQRCMRIL
EEFRAYLPLLIKLGNLQLQDPNTQSLLRALGLGSQRSLDLLTLGQMLNYPLLEFADR--I
NQVWQYDKERIHAQEILQQMQQYWEGRQLRLLNFILQVPYKPPTPERSKRP---ALRSPQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGYLHKIALEWVTIMYGLG---
ALLEVWVAFQQKWIFLNKVLHEMKIEFPAPELNARFKAMDDQYRTLMRISVADPMVLSLI
-VPNTKRSPYFQGQHLQQMLKAGSGELEAIIMALEDVLYGVCANFPRLFFLSDSELVALL
AAPLDTCEAQPWAQRCFPYIKAVNFRSKSTK-NKN--I-QD----SSSSTETAETIAVLA
ACGEEVKLQEPLPLHPDLPKWLASLEKCLRFVIVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLIKALKA---
MPQQTQMP----MQVYVQHWLDAVQVFPWQCILVAEEVVWRAEMEEALLESRTMHMSSVH
VHNLEVLVQFIRSQRSSQDGQSPPSVRQTSLFSTLLVKAVTHRDIAQLLEKNQVSDLTDF
HWVRQLKYHLGSSHLNLKSPLQCLTTIAS-TEPSVSPAACWIDVLGRSFM

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYMGPKL
GPLPSLMHERQVFILLMALDEVAYGAILGRDGLGKAETVNSLAWTLGRQLVIMPCLPQIE
FRCLRNYLNGALQGGAWLLLENVNQLPSSLLSALGQRLDELHYLYAPLYQKASKNISTIN
-------PTKPLLLGAGFFEKHQVSMHLGFGCFLTLHSLGPHVPANLHLLLRPVALAL-P
DLQRVAELNLLGAGVQDASRMASRLSKLFSLERELVSGNLPCRLPLLKQVLEHTIQTLNT
SQ-EKKLQQSYNPAASEEAALLRALLHSPLFSILDGLRLQKLQELLCGIFPNASHVLAEP
VSHKLIKSVVVEELQQLGLFPTSNTLTSLEQLSQALSRASGILLLGPAGSGKSTCWRSLF
KIQNRLAAMEHT----STKGFQSVEIVHLYPSVLNSKEYLGWSEGPSWHYGIFPKLLHAA
PYCKSVGSEVPSEKFTGIQQWIICDGAPNHAWTDSVTCLLRDPPQLSLPNGQQIARPLGT
FFLIEVAEAAGMSPTVLGRCALVWCSGEQTWQSMLSVLMASLPHEYHLQQETITEFNYLA
EVLVPSVLRFLTRIGASSQLQVH-GHQAVCPGVAEVTSLARILRALLDPLLHLLEEEKSY
--TKEDFSGSDLVTQ---NFKSSKA-----RVQSDRVSVNKKQRRHLLAISIFLFAIIWG
FGAH--------------LPS-RH-WPLFDDFMKKSISSLPNYPEPPPSALVFDLHVNLE
DGTLVPFTGQYLSTHVKGNLGSFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2782)

SQTEQLLYVVDLLLSNGQPVLLAGEIATGKSAFV
EVLVKPNYPAIHSPIHPALNSTHLRHLLSRGVHGQTQT-SSFPGHHQDSKGSILFLMEDL
HLAAFDPEKNCQPVLETLRQAMEGTIYAHNTLELQTLQTTVNFLATATVPGYSERPLCPR
LYRLFTVLALKSITQDTLLSRHVPSIQAWLERFPSVEREHTLARALVRASVEAWEAVCKC
FMPSPLRPHYRFSPHSVSHVL

ENSGT00910000144015_1_Linker_5_6 (2782, 3072)

GSLQLLPTRMGSRGFVESFHHQEYLRRVSGLRGTRLNVM
MSMRVMVRLWLHEAQRTFCDRLDSDRERSHCAKLLLEVAQNVFCGGPGSESLAKDCEEEE
------VEEEKVPEVESEEEIAQWETL-----SNSDSGSEEEEDPFGLQATTGSFLSESS
LAPFPR--K--SVNKENTENVSQ--MAEQEEDIRDSSRKLQAKT-PKHEWQMAPQ-MDLS
LPL--LLPVLLFYPQESPSDLVFSLELTLGSNFESPN-LYLERQWENLEKQLAASAVRLK
MNSSFSQCPVM

PF12780 // ENSGT00910000144015_1_Domain_6 (3072, 3331)

VQHVAHLVRVLARPRQHALLLSEFRGTGRYTAIILASNICQAHLLYLSV
-ESEEAIFQCLRDASWHAGMLNQPVALLVPDGVNVATFCRLLALATSGSFPDQYTEADLD
NIEENF-PKENIVIKYATKRDTVLNRFYQQVCNNLHM-FFMVGD--NQAQNQLPPTLFLT
LLQLTIASVERYEPWDQASLVRIAQFHLEND-HSLPLDDGSLKCPDFKHLIPNVANIMAR
IHVSSAYYHNHMCPGLPLVTPKTFLDFLDM

ENSGT00910000144015_1_Linker_6_7 (3331, 3453)

FLQQQQQMILQMRMRASRIQTALKTLRLMV
ERHSTQTNMLTDLETQLKGSYKS------------VGIYQGQLEQSKIQYRQKMVECQHQ
ESLIENLVRQHDALKAQHEVFLEQMGKAFVGP

PF12777 // ENSGT00910000144015_1_Domain_7 (3453, 3687)

LSQLQVADFEEIRSYRAPPESVVKVTDA
LCDLFHQETGWSSAKQLLCTEDFYQELVFFPKEKLTDSELVKLNEALRAPGMSDAALRSV
SIPAANLAIWLWAVLRYGLAQRRGLPTGLLLRQVDATLAREQARLGQFQFQAHDLLEQTW
SLAKKLEDAQVSHNHVVETLNQAQCGHFHKWPMKSALLTPMHMWTTQLQKLQEQAKTVFG
DALLCSAAIIYLGPFPPQRRQELLEKWLSLCQGSE---EALDPDDVAQALRQ--KSVVV-
-PKNPLLPTRTPFSILTLLSYGSEQHQWDRDLKPQAKSARLLGLLLRSHIHFSSSRWPLL
IDPSNQAIMWLNPLPPKQNRSLEPSPKESIEKYHV----TNQDSGDNTEDELEDENN-AE
EDEANEQRKEQKAKENKS--EK---------ENEQEVQETEKENEPESSS--SHSSLPSE
TQ-SLPSCLTVLSGTDPEL--GPQLLEAAANGLPVLLTNVE--LSLGCQELQWLLSKKNL
SPPSVQPGFCLFLSTTFPIHALSQ----VLGFELLKGLNVLDLGLNMEILEEQMLHEILC
RERPELETRWQDLKIRAADTYEAMKAFEEQLLVTLLRQ--NQKRQKPSKFLRKMVRTQAK
ICQLNAQMEELEDQKLEVVALWAPYRPVAYHGMAMVEALSPLQNLLPSFCMTSENWLAVI
RRAIDSMESYDSYRGEDLPSHLLRLKIHLARQLLTNTVVALGLIQTPLVGAFGALAMLQV
TKKVPKLERLALWPGLSASPCSGHNMQIPGVIRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLSSRAWEECGALELLPPFAGLCES
LAGHSDVWQDYLSLSSTVLGPAPG--PNSEPLSLFQKLILWRVLRPDCLAGALADLTTSL
LGRPLDENLGAPTMIFEHIQPTQPILILLPPPGHPTTTLHPVTVIRKLAANHEK-VPQKR
LHVIALGSEDWDPVSTVVNTLCQAMLQGHWLVLDNCHLMP----FWPRELLQPLQGLLDR
ARVVSDSEL---LAEPESRNVVTVHRDFRLWLIVPTEASTSLPGMLTQSSMPVFWNQSLE
LGRILIDSLD-SQQGLCTQP-LTQTLPLLFLHGLLLHRQLYGLKLQAHRGRWSQVTLTRA
LQIQEQLWVSLRNPSAAFLELTASVLYGGSLGDLEDREALVSLTRTCLNPRNTNWDQPHT
PQNLLATLMPSPELGELDARTDCKAQMHLLPTPPEPRTCGLNEAPQAWLVRRQSRVLLNA
LQKCSSTWVPTVCGGI--AQRKERRLRQRLAQAKKRLVALQALLTNNR--FRSGQCVTPW
AVLGPNARRPLEGFLETEVLELKHLVGTLLRDLDCLLQQLKGGTPCTSSRCAKVARALWA
GHLPQPWRSHALAGPQLPWLWLRQLSRRGHLLIHYLDSGMSENANEPERIFHLSAFRHPG
RLLLALRWEAVLE--------HNRNLPGHQGSISG-----SLPPKWQELSNHPLHIWVEN
GPNPKVPKMGL-LLIGLQLQHAEWDQTDGALQDTFSSQPCPLPPVSVSTQARGGKDAPVS
AGLGMYSCPVYMTGPLGTTKLHSKNILMHLPLPTRLSPDTCIQRRVHVCSPTLT

------------------------------------------------------------
---MKPYQHIS-LSSLPLPPVPLTPGETQQPGAWNWQSEPEQWARSVRQQLNAQLLLVSE
-PKADLSPEEASPEALES-QHSVCVP-DTEEQLQDRQRTQRQSPKAVSQSEQPTALELLV
AELQTLFSAVLRDGSPAAWHYLHAVLRLLPPYRVLLVGHLDLLPFLEQLSHWAPWVQSQL
QLDLLDAIEQAFPPDTSLLESASHIECCSQKQKFRHRPPHPVCPFVQARWGGQHVGEELA
TWLRPLTLPELQRSLGIVGAQVALKETWWLDGLSLLPLALATDIPVRYESRDTDDAEEEP
VGRKETKSQLDTQVPGKKTLQKRSSGFSFQTSLLGSQVMTIMKTERYLKKIHFLYLNVAP
SRHFRPYSLVVVPPKKVNPEHYIFSPFGILHVHPVEGSETITLGTWHRHSVLWQQLQSIP
FFKYCLLYKALACWKRSVKLHGLHRHRTFLGKHLLFAVPHFGAGLLHISRLLQELRSVSW
LPRDPNQCYGLLDLQRALAKENHKALQLLHRCLHLCTSILHLVHEDTYHMQQGLQERLKN
CKRIRTDQLSVYLQKVQGQQLEQKLRQTEAWLLRLGQLARLVDHMIGQNLVSIIEEEITS
FVANILQAPRQNPFLSAELVFDDCGQLSHEPCIENMIQILTGGLQSVKASALKVMQSTDL
KTPWDSLI--SEEEDEEEDSNKEFIMPKLQGQPSDAVHIFCGPNIGLVWPWKSHTVTEAL
EVRGCRLRGQYLPPNYKQLQEDLDNSPRIQQALTLQQALLEGMLWEVKEFCKEHHWMTGI
HEFLQAWGPQKLESMRGCPIKNYMMLVSRVNMWQTDVSNIPKKLITKGRLLQLNCYHIQA
EMESKLDGIRKDILTHVQNECWTRSQQLITELTDFTEVFQTINSDIHTIARCSQKLNQAN
EQYAELEKRMEYIRALHELIRNHFSLFSAENEALDIS-----------------------
-------LLDVWEAFQFEKSQASEFLLSKRHAIVPKLQQLIAAALVELEGLIENALSGPF
MDPAQEQRSMERQLISLERQFQNTASHLSELHHAYATFTGEESPVPLPVCGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRLISENISEWKCMAFAKFSMTIAQEKTDGWLTEAARLSTTLGLHSPVLQRCMHML
EEFRIYLPILSKLGSFQLQNLNFQVLLRALGLGSLQNTELLTLGQLLTCPLLEFADQ--I
NQIWQCENEQIRAQETLRRLQRVWEARQLRLMNFILYVPYEPPALERSKRQ---MFHSPQ
WEVVSKDSGTFILSDYSSLQDSIQESLQVLFKILAIQKSGDLNKIALEWVTIMHSLS---
ALLEVWVTFQQKWIFLNKVLYEMKIEFPSSSLNSRFKAMDDQYRILMQTSVADPLVLSLV
-VPSIKRSPHFRGQQLQQLLQAGSVELEGIIMALETVLYGVCADFPRLFFLSNSELVALL
AAPLESCEAQLWVRRCFPHVYAVSFNSSLTD-KN-TDDRDS----SPKPSTQVEAFAVLG
AGGEEVKLQGSVPLHPDLPKWLAHLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVASRLALGPSLDEAFKQ---
LPQQGQLP----LQLCVHHWLDLVQAFPWQCVMVAEEVVWWAEMEEALLEGRTLAMVPTH
VRKLEALVHFIRAHRASQGGQPLSSVRQTSLLSALLATAVTHRDIAQLLEEHQVSDLTDF
HWARQLKYHLGSPHIVPQKPLQSLKTIAS-TETSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GSLPSLLPERPALVLLLALEEVACGALLGPEGVGKTDMVKSMAQALGRQLVTMPCLPQTE
AQSLSNYLNGALQGGAWLLLEEAQRLPLGLLSALGQRLTQLHHLCAPLYQEASRSTSTVD
-------PTHPQLLGSGVFEKHHVYIHLCYGCFLTLRSLSPAVPANLHLLLRPVALTL-P
DLQQVAELTLLGAGMRDASRMASRLSKFFSLERELVSASLPCRLPLLKQVLEDTIQDLHV
TK-EPKSQQPHSLAVNEEAALLRALLRSPLFSILSGVHLHNLQELLCGLFPNARQVLAEP
VTHTLRKPLLVEELQQIGLHPSPDILGSLEQLSQALSRVSGVLLLGPAGSGKTTCWHSLF
KIQNRLAAREDT----SAQGSQPVEITHLYPNVLSPQEFLGWLEGPCWHHGVFPRLFRAA
NPCKTAGPKGPPQESVGIQHWIICDGVASAAWLDSITCLLSDAPQLSLPNGQQIARPPGT
FLLMEVGDATGMSPKVAGRCALVWCGGEQTWQSMLSVLMATLPHEYRLQPQTVTELNRLA
QALVPATFRFLTRQGASSLLQVH-GQQAVCPGVAEVTSLARILRGLLGPHLRIDEGEKAH
--VSEDLSCSDPVAQ---SFKSSKSSSL-NPSQVASDDVPNKCKEHSLAVSSFLFALVWG
FGAH--------------LPS-RL-WPLFDSFMRGSISCLCNYLEPLPSALVFDLHVCPE
NGTLVPFTGHYLGSRIRGIPGTFNPSP

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2782)

QTERLLYVVDLLLSEGHPVLLAGEAATGKSTFV
EMLVEPHHPYTYSPIHSAFSPTHLRLLLSQGVQGQVQA-APSPGPHLDSKGSLLFLLEDL
HLATSNPEKTCQPVLETLRQAIDGTVYAHSTLELQMLQPLVNFLATATVPGFCELPLCPR
LFRLFTVLALGSMTQAILLSRHTPSIQAWLERFPSVEREGVLAKALVRASVEAWEAVGNC
FMPSPLHPHYRFSLHSVSQLL

ENSGT00910000144015_1_Linker_5_6 (2782, 3072)

GSLQLLPTRMGSRGFLDVPNHQEHLHRVSGLRGTRLTVM
MATRNMVRLWLHEAQRIFCDRLDSPRERSYCANLLLEVAQSVFCCEPAPQHGGKGYEEEE
E-----DEEERVPEVESEGELAQWEDL-----SNSGSETEEEDDPYGLQVTTGSPSNDSG
LAPST---A--PVKKESTEIISQ--DTSQEEGTKTCSCKLQLNR-NKSWWQKTTQ-MDLV
SPL--LLPVLLLCPWEKPSDLVFSQELTLGSNSESPS-LYLERQWESLEEQLSTTASQLK
LNASLASCHAM

PF12780 // ENSGT00910000144015_1_Domain_6 (3072, 3329)

AMHVARLVRVLARPRQHGILLSGALGTGRRTAITLAASIYQAHLFHLPS
-GSEEAILQCLRDASWHAGMLGQPVALLVPKGVDLTTLHRLLALATSGSFPDQYTEADLE
SIEEHL-PKENLSVKQNIKKEVLLHRFYQQVCNHLHI-FILIGD--DQAHKQLPSTLYLR
LLQLAIASIDRYEPWDQDSLISVVRHYLEGA-QNPSIDDDSLKCPDLQASIPSVAKAMAL
IHLSAASYHGHLCPELPLVTPKTFLDFL

ENSGT00910000144015_1_Linker_6_7 (3329, 3452)

DTFVLLQQQMTLQIKKKAQRIQNALENLRMLM
EKHNAHTNFVFNLEQLLKSSRKN------------LHILQQQLQQDKLLYRRQLAECQQQ
EDLIKNLTKQRDALRAQYEAFLEQMGKAFLG

PF12777 // ENSGT00910000144015_1_Domain_7 (3452, 3687)

PLSQLQVADFEELRSYRVPPESVVRVTDA
LCDLFHCETGWASAKQLLCTEDFYQELVFFPKEKMTDSEMIKLAQALKAPGMSDAALRAV
SIPAASLAAWLWAVLRYGLAQRRGLPTGLLLRQIEGTLAREQALLGHRQFQAQETLEHKL
DVANKLEDSWVSHNRVMENLIRAQCGQYHKWPIKSALLTPMQSWTTELQKLKGHCTTMFG
DALLCSAAIIYLGPFPALRRQELLDKWLALCRGFQ---EPLGPDDVAQALKQKQKSAIMP
-PKNPLLSTRSPFNLLTLLSSKSEQFQWDRDLKPQAKSARLAGLLLRSHTHYSSFRWPLL
LDPSNQAPIWLNPLPLQETRCLAPGPG------MG----FVRNQEKEEAMEEED-DNSED
SDKTKGKTKEQK-TEDRENEEEGNKQEHEEEEEEEEEEEEEEEEEEEEKTERQRSRPASE
TGALPLPSLSVLSGTDPEL--GPQLQEAAASGLPVLLTNME--LGLGCQELQWLLQREKL
SPPQVQPSFCLYLSTTLPLNALEK----VLGYELLKGLNVLDLSLNMEILEEQMLHEILC
VECPELESRWQDIKIRTLDSFEAVEAAEEGLLLMLLLQ--NPKHQKPAKFLREMVRAQAK
LCQLRAHCEELEEMRRQEVVLWAPYRRVVWHGMAIIKALSPLQNLLPLFRMHPDNWLAAT
KRALNSMEQYKIHQGEDLPSHLLQLRTQLTRQLLGSTVAALGLTQLPLVGALGALALLQV
ARKAPELERLALWPGLAASPSTGYSKP--SVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5028)

AWLGLKAWQECRMLELLPPFAGLCAS
LAHHSNVWQAYLSLSSTVLGPAPG--PGPDPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENLDASTIPLEHSQATQPLLILLPPPGHPTATMHPLTVIQKLAARHEQ--GQKH
LEVIALGSEAWDPVSVVVSTLCQAMHKGHWLVLENCHLMP----HWPKELLQPLWRLLDG
ARVVSDLESELLLAQPASRNMATVHRDFRLWLILSAEAIASLPAVLTQHSMPVFWDQSLE
LGHVLINSMELAQQGQNVQS-PTRTVPLVLLHGLLLYRQLYGMKLQAHRGRWSQVTLTQV
LQIQDQLWASLSNPSAAMQELAASVFYGGPVGDSKDREALTRLTQACLSPSSGSWAQPHT
PQYLLATLLPSPELGELDALAECKAQMHLLPTPPEPQSCGLSAGPRAWLLHRKSRALLSA
LQRSLPVWVPAARGGS---RRTERRLRQRLVQAKRRLESLQALLMDTARPEES---GAGW
VVP---RQRPLQAFLQTEVLELSQLARTVLCDLDCLLQQLKGAPPCASRRCAAVAHALWT
GCLPPPWRPYALAGPQPPWHWLRQLSRRGQLLVRYLGVD----AQVPGRIFHLSAFCHPR
RLLLSLRSEATFATGALHQRVPSSNLPECQGPGFS-----GLPYKRQELNSNPLHLQVVN
SPNPTVPEMGL-LLIGLQLRNAEWDPLAGALQDSTSSQPCPLPPVSVCVQARGANDLTPP
AGLAVYSCPVYMEGPLGIVRLHSRNILMYLPLPTKLSPATCDQLRVHVCSPPLP

------------------------------------------------------------
----------------------------MSCGQLEWSLTSTSV----SLPFHCFLYRLGQ
--VRSSS----QEPGTGN-QSLISGR-EAEEQPRDHHRKQRQFLKAVTQSQHPPALELLV
AELQALFSAVLQDGSPAAWHYLHAVLRQLPPYRALFVGRLDLLPFLEQLSNWAPWVQSQF
QLDLLDAIEQAFPPDTSLLEGTSHVKCCPQKQKFHRGPPHPACPFVQALWGGQQVGEELA
TWLRPLTLPELQHSLGIVGAQVALKEAWWLDGLSLLPLALATDIPIQYESRGTDDAAEEL
VGRKETKPQLGSEVPGKKT------RFSPQTSLLGSQVMNILKTERYLKKIHFLYLNVAP
SRYFRPYDLMVVPPKKVNPEHYIFSPFGVLHIHPVEGSETMTLGTWHRHSVLWQQLQFIP
FFKYCLLYKALARWKRSMTLQRLHRCRTFLGKHLLLAVPHFGAGLLHISRLLQELRSVPW
LPQDRDRCYELLDLQQALAKENHKALRLLCRCLHLCTSILQLVHEDTYHMQQGLQERVKN
CKRIRTDQRSVYLQRVQCQQLEQKLKQAEAWLLRLGQLARLIHYMICQSLVSIVEEEITS
FVANILQPPRKKPFLSAQLVFDSCGQLSPEPCIETMIQILNVGLESVKTSVLKVMQSTDL
KTPCHALY--SEEEDEEEDSNTEFAMPKLQGQPSDAVHIFCGPNIGLVWPWKSHTITEAL
EVRGYRLRGQYLPPSYKQLQEDLDNNPRIQQALTMQQALLEGMLHEVKEFCREYRWMTSI
HQFLQAWGPKKLESMRGGPLKNYVMLVSCLNLWQTRVSNIPNKLVTKGRLMLLGCHHIQS
EMESKLESIRKDVLTHVQNECWTRSQQLITELMDFTEVFQTINSDIHTIAQCSQKLNEAS
EQYNTLEEQVEYIRSLHELIRNHFSIFSAENEALDIS-----------------------
-------LLDVWEAFQFEKSQASEFLLSKRHAIVPKLKQLIAAALVELEGLIDKALSGPF
MDPTQEQRSTERQLISLERQFQNTASHLSELHHAYATFTGDKSPVPLPVCGTRP

PF08393 // ENSGT00910000144015_1_Domain_0 (1135, 1294)

IVQQQR
IWHLYRVISENISEWKCMAFAKFSMTMAQEKTEGWLMEATHMSTSLELHSPVLQCCIRMV
EEFRSYLPLLTKLGSLQLQ--NFQALLQALGLDSLCNMELLTLGQLLTCPLLDFADR--I
NQIWQCENERIHAQDTLRRLQRVWEARQLRLIN

ENSGT00910000144015_1_Linker_0_1 (1294, 1326)

FILHVPYEPPGGERPKKQ---MVRSPQ
WEVVG

PF08393 // ENSGT00910000144015_1_Domain_1 (1326, 1602)

KDSGTFILSDYGSLQDSIQESLQVLFKILAIQKSGDLNKAALEWVTIMHSLS---
ALLEVWVTFQQQWIFLNKVLHEMKIEFPSPDLNSRFKATDDQYRTLMQISVDDPWVLSLI
-VPSVKRSPHFQGQQLQQLLQAGSVELEGIIMALKSVLYRVCAHFPRLFFLSDSELVALL
AAPLESCEAQLWVRRCFPHVHAVSFTSSPLD-EK-VDDREA----SPNALTWVEALAVLG
AGGEEVKLLRSIPLHSDLPKWLASLEKCLRRALVHKLQGCVASRLTLGPSLDEASKQ---
LPQESQLA----PQLFAHHWLHIVQAFPWQCVLVAEEVVWRAEMEEALLEGKTPAMVRVH
VCKLEALVNFIRAQRASQGEQPLGSVRQASLLSALLAMAVTHRDIAQLLQEHQVSDLTDF
HWARQLKYHLGSPHVIPQSPLQSLKTIAS-AVTSPSPAACWIDVLGRSFLYNYEYLGPRL
GSLPSLLPERPALVLLLALEEVACGTLLGPDGVGKATTVKSLARALGRQLVTMPCLPQIE
AQSLSNYLNGALQGGAWLLLEAAQRLPLGLLSALGQRLAELHHLYAPLYQAASRSPSTVD
-------PTQPQLLGSGFFEKHHVYIRLGYGSLLTLRSLSPAVPANLHLLLRPVALTL-P
DLQQVAELTLLGAGMRDASRMASRLSKFFSLELELVSAPLPCRLPLLQQILEDMIQNLNV
TKEEPRSQQPHSLAVTEEAALLRALLRSPLFSTLSGLHLHNLQELLCGLFPNARQVLAEP
EAYTPRKPLLVEELLQIGIHPSPDILGSLEQLSQALGRALGIILLGPAGSGKTTCWHSLF
KIQNQLAAREDA----STQGYQPVEVTHLYPNVLSPQEFLGWLEGPCWHHGVFPRLLRAA
SMYKTVGLRGPPQESVGIQHWIVCDGVANASWLDPITCLLKDAPQLSLPSGQQIARPPGT
FLLMEVGDATGMSPTVVSQCALVWCGGEQTWQGMLSVLMAALPHEYHLHLHTVAELNHLA
EVLVPATFQFLTCQGASSLLHVH-GQRALCPGVAEVTSLARILRCLLDPHLRIDEGEKAH
--ISEDLSFSDPVAQ---SFKSSKSSSL-NPSQVDNDDAPNQRKKHLLAVSSFLFALIWG
FGAH--------------LPS-RL-WPLFDTFLRGSISCLSNYPEPPPSALVFDLHVCPD
NGTLVPFTGHYLGSRIRGTLGAFSPSPQTERLLYVVDLLLSEGHPVLLAGEAATGKSTFV
EVLVEPHHPYVCSPIHPAFTPIHLRLLLSRGVQGQAQA-APWPGHHLDSKGSLLFLLEDL
HLAASDPGKSCQPVLETLRQAVDGTVYGHSTLELQTLQPVVNFLATATVPGFCERPLCPR
LFRLFTVLALGSVTQAMLLSRHTPSIQAWLERFPSVEREVVLAKALVQASLEAWEAVGSC
FLPSPLHPHYRFSLHSVSQLLGSLQLLPTRMGSRGFLDCPSHQEHLRRVSGLRGTRLMIM
MAMRNMVRLWLHEAQRTFCDRLDSPRERSYCAKLLLGVAQSVFCCGPAPQNGGKGSEEEE
E----EEEEERVPEVESEGELAQWEDL----ISNSGSETEEEEDPYSLDVTTSSPSGDSG
RAPSI---V--PVKRETIETLSP--KMSQEEGTKASGYKLQLNR-SKIWWQKTAQ-MDLA
TPL--LLPVLLLRPQEKPSDLVFSQELTLGSNSESPN-LYLERQWESLEEQLSTSAAQLK
LSAHLARCHSIAKHVARLVRVLARPRQHGLLLSRALGTGRRTAISLAASIYQARLFHLPS
-GSEEAILQCLRDASWHAGMLGQPVALLVPKGVDLTTLHRLLALATWGSFPDQYTEADLD
SIEEHL-PRENLSVKQNIKKETLLQRFYQQVCNHLHM-FILIGD--DQIHGELPSTLFLR
LLQLAIASIDRYEPWDQDSLISVVRYYLEGA-QNVST-DDSLKCPDLQASIPRVAKAMAL
IHLSAVSYYGHLCPELPLVTPKTFLDFLDTFTLLQQQMTLQIKNKFQRIQNALGHLRMII
KKHNTYTNFVFNLEQLLKTSCKN------------VTTLQQQLQKGRLLIKQQLAECQQQ
ENLIETLTKQRDNLRAQHEAFLEQMGKAFLGPLSQLQVADFEEIRSYRAPPESVVQVTDA
LCDLFHCETGWASAKQLLCTEDFYQELVFFPKEKMTDSEMIKLTQALNAPGMSDAALRAV
SIPAANLAAWLWAVLRYGLAQRRGLPTGLLLRQIEATLAREQAHLGRCQFQAQETLEHNL
DLAKTLEEARASSNQMIENLNQAQCGQYHKWPIKAALLTPVHSWTTELQKLKGHCLTVFG
DALVCSAAIIYLGPFPPVRRQELLDKWLALCRGFQ---EPLGPDDVAQAWKQMQKSVVMP
-PKNPLLSIRSPFSLLSLLSSESEQLQWDRDLKPQAKSARLAGLLLRSNTHYSSCRWPLV
LDPDNQALIWLNPLPQQETRSLVPDLTEHREKGFV----R--NQEEEEATE-EEDDSSEG
CDKAKNKTKEQK-TQDRENEEEREKEE--------------EQEQEEDETERQESRPASE
TGSLPLPNLHVLSGADPEL--GPQLREAAANGLPVLLTNME--LGLGCQELQWLLQREEL
SHPQVQPGFCLYLSTTVPLSALKK----VLGYELLKRMNVLDLSLNMDTLEDQMLHEILC
AECPELKNRWEDLKTRALDSCESVKAAEERLLRMLLLQ--NPKHQNPAKFLRDMVRAQAE
LCQLRARCEDLEDLRLQEVALWAPYRHVVWHGMAIIKALSPLQNLLPLFRMSPDNWLAAT
KRALNSMKQCETHQGEDLPSHLLHLRVQLTRQLLGSTVAALSLTQVPLVGALGALALLRM
ARKAPELERLAFWPGLAASPSTSYSNP--GVA

PF03028 // ENSGT00910000144015_1_Domain_9 (4233, 4690)

RPAWLGVRAWRECSMLELLPPFAGLCAS
LAGHSSVWQAYLSLSSTVLGPAPG--PGPDPLSLLQKLILWRVLRPECLAGALADFTTCL
LGRPLDENLGASTIPFEHSQATRPMLILLPPPGHPTATKHPLTIIQKLAAGHEQ--GQKH
LEVIAVGSEAWDPVSVVVSTLCQAMHRGHWLVLENCHLMP----HWPKELLQPLLGLLDG
ARVVSDLELELPLVQPTSKSVTTVHRDFRLWLILPAEAVASLPAVLAQHSMPVFWDQSLE
LGHILTDSLELAQQGLSAQP-PARMLPLLLLHGLLLHRQLYGMKLQAHRGCWSQVTLTQV
LQIQDQLWTSLSNPSAAMQELAASVFYGGPLGDKKDREALISLTQACLNPSNGSWAQPHT
PQYLLSALLPSPELGEPDALAECRAQMHLLPTPPEPQSCGLSVGSQAWLLRRQSRTLLSA
LQQTLPTWVPASRGSS---RRAEKRLR---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MVPE
EKRVGLSSDETSSDALKSW-HSICVL-DSKEEPLACQQRQRQFVKPATESEQPTVLELLL
AELRTLFSAALQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAINQAFPPDSSLLDSASHADCCPQKQRLHHRPPCPACPFVQARWSRQQEKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRRETRSQLDYEVPREKTLQKSSTGFSPETSFLGSQVMTALKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNAEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQKALAKEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRAGQGSIYLQRVQRKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILEEQITS
FVANILQAPRQKPFLASQLVFDDHDQLSHVPCVENMIQILTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKTEFLTPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVRGYRLRGQYFPRDYKQLEEDLNNNPQIQQALNIQQVLLEGVLWEVQEFCREHHWITGI
YEFLQSWVPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPVELLTKGKLLLLSCRDVQT
EMESKLDSIRKDILAQVQNECWSLSQQLMTELTNFMHVFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFRESPIPPRPPPPQPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIIPKLQQLMAAALAELEGLLGKALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSELHHAYVIFTEDETPVPLPICGTRP

PF08393 // ENSGT00910000144015_1_Domain_0 (1135, 1293)

IVQQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTEGWLTEAARMSTTLGLNSPVLQHCMRIL
GEFRSYLPLLAKLGSLQPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIRQLQRYWEVRQLRLL

ENSGT00910000144015_1_Linker_0_1 (1293, 1326)

NFILHVPYEPPAAERSKRQ---VLRSPQ
WKVVD

PF08393 // ENSGT00910000144015_1_Domain_1 (1326, 1602)

KDSGTFILSDYSNLQDSIQESLQVLSKILAIQKSGDLNKIALEWMAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVRFKSCPTG-EKNMDDWES----SLNAQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFLRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTTS-SEHSLSPAACWVDVLGRSFLYNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
TQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHSLYAPLYQEASRNTSTID
-------PTQPQLLGSGFFENHHVSMRLGYGCLLVLRTLSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLEHELVSGPLPCRLPLLKQILEDTIQTLNV
TKEEPKCQQPRSLAAIEEAALLHALLHSPLFSVLNGLHLHNLRGLLCVLFPSASQVLAEA
MPYKLMKALVVEELQQVGLHPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESMGIQHWIICDGASSAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADATGMSPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNHMA
EVLVPATFRFLARQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDPHLRLKE-KAP-
--GPEDLSCSDPVAQ---SFRSSKSSFL-NRSQVDSDDVPNRRREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHASIQTERLLYVVDLLLSGGQPVLLAGEAATGKSVFV
EVLVEPHHPYIYSPIHPAFSSTHLRLLLSRGIQGQTQA-SPQPGHHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYVHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPVIQAWLERFPSVEREHALARALVRASVEAWEAVCNC
FMPSPLHPHYHFSPHSVSHLLSNLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTRLTIM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQNLGKDHEEDE
------EEEGRVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVATGSNSSDPS
LTPSI---G--PVSRGMRESISH--KIRQEKGTRASNYRLQVRRSFKTWWQKAPQ-MDLV
SPL--LLPVLLLHPQEKPSDVVFSQELTLGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHLFHLPS
-GSEEDILQCLRDASWRAGLLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
RIEEHF-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQTHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-RSLPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLI
KEHGTHANLISDLEQQLKASSKS------------LSMFQQQLQQSKLLYKQQLEECRHQ
ENLIENLAKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKITDSQLIKLHLILKAPGMSDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLIREQARLGYYQFQAQETLENNL
ALAKMVEDAQASHNCVAKTLSQAQRGQYHKWPMKAALLMPMHAWTIQLQKLKGHCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKTPLLATHCPFNILSLLSSASEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALMWLDPLPLAENRCLAPAPTEGRGKGLM----RNQNTENK-MDMKEEDDDSED
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RECPELETRWQNLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNMVRAQGK
LCQLRAHCEELEGQKLQEMVSWAPYRPVVWHGIAMVKALSQLQKLLPLFRMSPEKWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQA
TGKASELERLALWPGLAASPSTVHSKPVSGVAR

PF03028 // ENSGT00910000144015_1_Domain_9 (4234, 5024)

PAWLGPKAWHECEMLELLPPFVGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRILRPECLAGALADFTTSL
LGRPLDENMGAPTMPFKHSRATQPMLILLPLPGHPTATLHPLTVIQNLAAKYQQSPGQKH
LQVIALGSEVWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLGQPESRNVATVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-PTQALPLLLLHGLMLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPCAAMQELAASVFYGGPLGDTEDREALFSLTQACLSPSSRNWVQPHT
PQSLLARLMPLPELREPDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRVLLSA
LQQSSPVWVPESRGGA---QLAERRLRQRLVQVNRRLESLQDLLTNLVRQDES---GAPR
SVLGPNARRPLEGVLETEALELSRLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRSHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADANSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGAVSG-----PLPYKRLEMNSNPLHFRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSSLPPVSISTQAPGTSDLPPP
ADLTVYSCPVYMGGPLGNTKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

------------------------------------------------------------
---MKPHPQAC-SSSLSMLSTSRRPGESQQPKNWNWHLNPELWARSVRQQLNTCLRFILE
ET-------K-------SG-FSECSC-SSQEHSWDCLKKQ-ELLKAVVESEQRTSLELLL
SELRSLLSAVLQDGSCEAWSYLHAVLGLLPPYREMLTGQLDLLPLLEQLYCWAPKVQSQL
HLDLLDAIDKAFPPDRSLLHSSSHVDCHPWMKRSHRRPLCPACPFVKALWSGQQK-RELA
TWLQPLTLPELQHSLGIVGAEVALDENQWLDSLSLLPLALATDIPVQYESSDADYGEGEP
AER---KSQLASESPEEKAFKKIS----SKTSLLRSQVKSLLNTDWYQKKIHFLYLNVAP
DRYFRPYNLIVVPPNKVNPEHYIFSPFGILHVHPVEGSEAMTLGTWHRNCAVWHELQQIP
FFKNCLLRKALTCWKKNVRLYGLHRIQTFLKNHLLLAVPHFGAGMLHISRLLQEFRSVSW
LPKEPDKCYELLDLQKTIAKETDKALQVFCHFLNLCASILHLVHEDTYQMQQGLQERVQN
WNRIRKGQGSIYLQRVLCRHLEKKLKQAETWLLKLGKFARLIDYMICQNLVSILENEITS
FVANTLQAPRQNPFLLSQLVFDDNDQLSPMPRIETIIESLTKDLQSMKTSALKAVQSTDL
RTSRDPLYSE---DDKDQDSNAEFQMPKFHGKPSDAVRLFCGPNVGFVWPWKTHAITDVL
EVRGHRLRGQYLHPNYNHVQEDLDNNAEIQQALAVQQALLEDMLQEVREFCNEQQWVEGI
YKFLKVWGPQKLEDLRGSPINDYVVLVSQLEDWQERVSNMPVQLLTKGKLLLLSGHDVQA
ELESKLSSMRKNIFAQVQSECWSRNQQLMTELTDFLRVFQTISSDIHAIAQCSQKLNEAN
EQYSQLEERVEYVRSLHDLIRNHCGLFIAENETLDIA-----------------------
-------LLDIWEAFQFERSQASEFLLSKRHSIVPKLLQLMAAALAELEGLLAKALSGPF
MDPSQEQRSTEHRLSALEQQFLNTLNNFNELCYTYCTFTGDESPMSPPASGSRS

PF08393 // ENSGT00910000144015_1_Domain_1 (1135, 1600)

IVQQQR
IWRLYRIISENFSEWKCMAFTKFSLSMAREKTDAWLTEAARLSTTLGLPSPVLQRCMRML
EEFRSYLPLLTKLGNLQLQNFSCQSLMRVLGLGSLQSFDLLTLGQLLNCPLLEFADR--I
NQVWQYEKERIHAQESLQQMQQYWEGRQLRLLNFILHVPYEPPASERSKRQ---TSRSPQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGELNKIALEWVTIMYGLG---
ALLEVWVAFQQKWIFLNKVLHEMKIQFPGAELNARFKVMDDQYRTLMRISVADPMVLSLI
-VPNAKRSPYFQGQHLQQLLKAGSVELEAIIMALEDVLYGVCAYFPRLFFLSDSELVALL
AAPLETCEAQSWARRCFPHIKAVKFRCSTDD-EKSKNNQES----SSSTQAPVETIAVLG
AYGEQVKLQSPLPLHPDLPKWLASLEKCLRLLIVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLVKSLKA---
LPQQRQVP----KQPYVQHWLDAIQVFPWQCILVAEEVVWRAEMEEVLLERGTMRTFSIH
VHKLEVLVQFIRAQRSSQSKQSLPSVRQTSLFSNLLVMTVTHRDIAQLLEKHQVSDLTDF
YWARQLKYHLGSSHLNSKSPLQCLKTIAA-AESFLSPAACWIDVLGRSFI

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPKL
GPLPTLMHERQVLVLLLALEEVACGTLLGRDGLGKTETVNSLTWTLGRQLVMMPCLPQIE
FRCLSNYLNGALQCGAWLLLENIHQLPPSLLSALGQRLDELHHLYAPLYQKASKNISTIN
-------PTKAPFLGAGFFEKHHVSMCLGYGCFLTFPALSPDIPANLHLLLRPVAFAL-P
DLHRVAELNLLGAGVQDASRMATRLSRLFSLERELVSGTLPCRLPLLKQVLEDTIQTLNA
TEEGNNSQQPQNLVAPEEAALLRALLHSPLFTTLDGLRLQKLRELLCGIFPNASHVLAEP
VTHRLMRSVVVEELQQLGLLPTPNTLMSLEQLSQALSRASGILLLGPAGSGKSTCWKSLL
KIQNRLAAMEQT----STQGFQSVEIAHLYPSVLSTQEFLGWSEGPSWHYGIFPKLLHAA
PHCKSVDSEEQLKEFTGIQQWIVCDGAPNSTWIDSITCLLSDPPQLSLPNGQQIARPLST
FFLMEVAEASGMSPTVVGRCALVWCCGEQTWQSMLNVLMASLPHEYHLLQETIVELNHLA
EVLVPAVFRFLTRIGASSLLQVH-GHQTVCPGVAEVTSLARILRALLDPHLPLYEEEKPR
--VQEDLNGSDLGTQ---SFKSSKN-----RVQFDSDNVNKKQRKHLLAISSFLFATIWG
FGAH--------------LPS-RH-WSVFDNFMRNSISSLSNYPELPPSALVFDLHVNLE
DGTLVPFSGHYLSSCVRGSLGTFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2783)

SQTERLLYVVDLLLSNGQPVLLAGEIATGKSAFV
KVLVEPNHPSIHSPIHPALSSTHLRHLLNRGVHGQSQV-GTFLMYHQDSKGSLLFLMEDL
HLAASDAERICQPVLETLRQAMEGTIYAWNTLELQTLQPTVNFLATATVPGYSERPLSPR
LFRLFTVLALENMTQDTLLRRHVPSIQAWLERIPSVEREHTLARALVRASVEAWMAVGNC
FMPSPLRPHYRFSLHSVSHILG

ENSGT00910000144015_1_Linker_5_6 (2783, 3072)

SLQLLPTRTGSRGFVDTFHHQEHLRRVSGLRGTRLTIM
MSMRIMVRLWLHEAQRTFCDRLDSDRERSHCANLLLQIAQSVFCCGPESQPLVKDYEE-E
------VEEEKVPEVESEGEIAQWEDL-----SNSDSESEKEEDPYGIQATTCSFLGDSS
LASFPV--K--SVNKENTEGVTQ--MAEQEEDITVSGGKLQSQA-PKNKWQTASQ-MDLT
LPL--LLPVLLLYPQEKPSDLVFSLELTLGSNVESSN-LYLERQWENLEKQLAASAARLK
LNPHLAQCHMM

PF12780 // ENSGT00910000144015_1_Domain_6 (3072, 3331)

TQHVARLVRVLARPRQHGLLLSVARGTGRHTAVSLASSIYQAHLFHLPS
-ESEEAVSQCLRDASWCAGVLNQPVALLVPDNVSVAIFHRLVALATSGSFPDQYTEADLD
NIEEHL-PKENLVVKLIMKKDTILHRFYQQVCSNLHM-FFLMGD--DQAQKQLPSTLFLR
LLQLATASVDRYEPWDQASLVRIAQCHLENV-QSLPLDDGSLKCPDIKALIPNVAKIMAL
IHLSSAYYHQHMCPELPLVTPKTFLDLLDM

ENSGT00910000144015_1_Linker_6_7 (3331, 3443)

FLLLQQQMILKMRMRAWRIHSALKILRLLA
ERHSNQTNLLTDLEKQLKGSYKN------------LGIYQAQLEQSKLLYRQKMAECQHQ
ESLIENLVRQQDALQAQQEAFL

PF12777 // ENSGT00910000144015_1_Domain_7 (3443, 3687)

EQMGKAFLGPLSQLQVADFEEIRSYRAPPEAVVQVTDA
LCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKLTDAELIKLNQALNAPGMSDAALRSV
SIPAANLAVWLWAVLHYGMAQRRGLPTGLLLRQVEATLAREQARLGQFQFQAHDLLEQTL
SLTKKLEDAQASYSLVMENLNQAQCGRYHRWPMKTALLTPMHMWTRQLQKLKDHCKTVFG
DALLCSAAIVYLGPFPPQRRQELLDKWLSLCQGFE---EPLEPDDVAQALKQ--KSVGVP
-PKNPLLPTRSPFRILTLLSCESEQHQWDRDLKPQAKSARLLGLLLRSHIHFSSCRWPLL
LDPSNQALVWLNPLPLKQDELLAPPSKDSKAKHSV----TNQDSEDETEDEGDNDNDKED
SSEASDQTTEQKIEENKS--EE----------VAEQEQETEKEKSES---ESLDSSVSSE
TP-SPPPCLTVLSGTDPEL--GPRLLEAAANGLPVLLTNTE--LSLGCKELHWLLSRENL
SPPHVQPGFCLYLSTTLPIHALAQ----VLGCELLKRLNVLDLGLNMKILEEQMLHEILC
RERPELETRWQDLKTRAVDTSEAVMATEERLLVILLLQ--NQQRQKPSKFLRAMVRTQAK
LCQLNAQKEEIEEQKLEEMALWTPYRQIVCHGMAIIEALSPLQNMLPFFCMHLENWLAVT
RRALDSMKPHDSYHGEDLASHLLQLKIHLTRQLLTSTVAALGLTQAPLVGALGALALLQV
TKKTPNLERLALWPGLSASPSIGHNTQVPGVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGLRAWQECGVLELLPPFAGLRAS
LAGHSSVWQDYLSLSSTVLGPAPG--LNSEPLSLLQKLILWRVLRPDCLAGALADLTTSL
IGRPLDEDLGAPTVIFEHNQATQPILILLPPPGHPTATLHPVTVIRKLAANHDK-VTQKH
LHVIALGSEDGDPVSTVVNTLCQAMLQGHWLVLDNCHLMP----HWPRELLQPLLELLDG
ARVVSDSEL---LAEPESRNVATVHRDFRLWLIVSTEASASLPGVLTQHSMSVLWDQSLE
LGRILIDSVS-SQQGLCMQP-LRKTLPLFLLHGLLLHRQLYGLKLQAHRGRWSQITLTKV
LQIQEHLWASLSNPSAALLELAASVFYGGSLGDPEDREALTSLTRACLSPRNKSWVRPHT
PQYLLATLMPSPELGELDAMTECKARMQLLPTPAEPRVCGLNEGPKYWLLRRQSRALLNM
LQQCSPTWVPSASRGS--AQRKERRLRQRLVQAKKRLVALQVLLTN-R--SRSGQCVTPW
AVLGPSAHRPLEGFLETEVLELRQLVGILQRDLDCLLQQLKGETPCTSSRCAAVAQALWA
GRLPRPWRSHAPAGPQLPWQWLRQLSRRGHLLIRYLDSGTSENANEPERIFHLSAFRHPR
RLLLALRWEAYLES-----SVPSPNRTGNQGSGSG-----SVPPKLQELNKRPLHIRVEN
GPNPKVPKMGL-LLTGLQLQYAEWDQMDGALQDSFSSQPSPLPPVSVSIQARGASDAPVS
AGLDVYSCPVYMTGPLDTTKLNSKNILMHLPLPTKLSPDTCIQRRVHVCSPTLS

------------------------------------------------------------
------------------------------------------------------------
-----VSDEEASSKALES-PRSVGVL-DKAEQRQACQRKKRQSLKAVTRSERPTVLELLV
AELQTLFSKVLQDGSPAAWNYLHAVLGLLPPYRALLVGRLDLLPFLERLYRWAPWVQAQL
HLDLLDAIDQAFPRDTSLLEGTSHVDCYPQKKRFHHGTPCPACPFVQAQWEGQQVEDDLA
TWLRPLTLPELQHSLGIVGAEVAMEETQWLDGLRLLPLALATDIPVQYESRDTDNAEEEP
VGRTETKSQLDLEVPEEKTHQKRSTGFLPQISLPGSQIMAVMKTERYLKKIHFLYLNVAP
SRYFTPYSLMVVPANKVNPEHYIFSPFGILHIHPVEGSEAMTLGTWHHHSVLWQQLQLIP
FFKYCLLRKALASWKKGVKLQRLHQHRSFLEKHLLLAVPHFGAGLLHVSRLLQELHSVSW
LPHEADQCYELLDLRRALAKENHKALRLLYRCLRLCTSILHLIHEDTYHMQQGLQKRLKN
CKRIRTDQTSVYLQKVQCEQLEQRLKQAEAWLLQMGQLARLVDYMICQNLVSIIEEEITS
FVANILQAPRQKPLLSAQLVFDSRGQLSHEPCIENMIQILTVGLRSTKASALKVMQSTDL
KAFWESLY--IEDEDEEDYSDSDFMMPKFQGQPSDAVDVFCGPNIGLVWPWKSRTVTEAL
EVHGHRLRGQYLPLDYKQLQEDLDNSSQIQQALAVQQALLEDMLQEVQEFCRDYHWMTGV
YEFLQAWGCQKLESMRGYPIKNYVMLVTRLNAWQAQVSGIPMELITRGRLLLLSCRNIRA
EMESKLVNIRKDILEQVQNECQSRSQQLITELTGFMKAFQTINSDIHSIAWCSQKLNEAN
ERYAELEEQMEYTRSLYELIRNHFGLFSAENEALDISVRRHLLCPSRC-SSPP-PPALLD
L-LSAPQLMDTWESFQYEKSQASEFLLSKRHAIVPKLQQLMATALAELEGVIEKALSGPF
MDPAQEQRSTERQLISLERQYQSTVSSLCDLHHAYTTFTGDESPVPLPVCGTRPI

PF08393 // ENSGT00910000144015_1_Domain_0 (1136, 1293)

VQQQH
IWHLYRVISENISEWKCMAFAKFNLALAQEKTDGWLTEAARVSATLGLHSPVLQRCMHML
EEFRSLLPLLNKLGSLQVQNLNCQALLRALGLSSLYSIELLTVGQLLSCPLLEFTDR--I
NQIWRTENIRTHAHEALLRLRRAWEARQLRLL

ENSGT00910000144015_1_Linker_0_1 (1293, 1326)

NFILHVPYESPVSERSKRQ---ATRSPQ
WQVVG

PF08393 // ENSGT00910000144015_1_Domain_1 (1326, 1602)

KDSGTFILSDYSRLQDSIHESLQVLFKILAIQKSGDLNRIALEWVTIMHGLS---
ALLQVWVTFQQKWIFLNKVLHEMQIQFPSPELSTRFEAMDAQYRTLMQISVADPLVLSLI
-VPSAKRNPLFQGQQLQQLLQEGSMDLEGIIMALESVLYAVRAHFPRLFFLSDSELVALL
AAPLESCEAQLWARRCFPHVHAVSFESSETA-KG-TDDPES----SPSIQTQVEALAVFG
VGGEEVQLRGPLPLHPDLPKWLASLEESLRLALVHNLQDCVAARLALGPSLDKAFKQENQ
LPQESQLP----VKMYVQHWLDLVQAFPWQCVLVAEEVVWWACMEEALLEERTLAMVPMH
VRKLEVLVHFLRAQRASQGEQPLPSVRQTSLLSALLVMAVTHRDISQLLQEHQVSGLTDF
HWVRQLKYHLGSPHTAPQSPLQGLKTAVS-TETFLSPAACWIDVLGRSFLYNYEYLGPRL
GSLPSLLPERPALVLLLALEEVACGTLLGPSGVGKAAIVKSLAQALGRQLVVMPCLPQME
ARSLSNYLNGALQGGAWLLLEAAQHLPLGLLSALGQRLAKLRHLYAPLYQEASRSTSTID
-------PTHPWLLGSSFFERHHVDMRLGYGCLLTLRALSPAMPANLRQLLRPVALTL-P
DLQQVAELTLLGAGIRDASRIATRLSKFFSLERELVSGPLPCRLPLLRKVLEDTIQALNV
TKEDPESEQSRSLATMEEATLLRTLLRSPLFSLLEGAHLQDLQKLLCGLFPTASQVLAEP
VTPRLRKSLLVEELRQGGLHPSPDILGSLDQLSQALGQASGILLLGPAGSGKTMCWHSLF
KIQNRLAAMEDP----TNQSCQPVEISHLYPGVLSPQEFLGWLEGPCWHNGVFPRLLREA
SQCRTMGPRGQVQESVGIHHWIICDGAASSSWLDSITCLLGDPPQLSLPNGQQIARPPGT
FLLMEMGDTTGMSPTVVGRCALVWCGGEQTWQGILSVLMAALPREYRLQPQTVTELSHLA
EGLVPATFQFLTCQGVSSLLQVH-GQRAICPGVAEVTSLARILRCLLNPYLRIDEEEKAH
--IPEDLSYSDSKCIVARSIKASKNSCL-HQSQIDSDAVPSKRREHLLAISSFLFAVIWG
FGAH--------------LPSSRL-WPLYDTFLRDSISCLSNYCELPPSDSVFDLHVCPE
DGTLAPFTGQYLGSRIKGTQGTFYPSPQTERLLYVVDLLLSEGHPVLLAGEAATGKTTFV
EVLVEPQHPYINSPVHPAVSTTHLRLLLSREVQGQSQA-GPWTARHLDSKGFLLFLLEDL
HLAASDPEKSCQPLLETLRQAIDGTVYTHSTLELQTLQPGVNFLATATVPGFCEQLLCPR
LSRLFTVLALGSVTQATLLSRHMPSIQAWLERFPSVERESVLARALVRASLEAWEAVGNC
FMPSPLRPHYRFSMHSVSQLLGSLQLLPIRVGSRGFVDCLNHQEHLRRVSGLRGTRLMIM
MATRNIVRLWLHEAQRTFCDRLDSLKERSFCARLLLEVAQNVFCCGPAPQSLGKGYEEEE
-------EEEKVPEVESEGELAQWEDL-----SNSGSETEEEEAPYDLPVITGSPCNDS-
-APPV---A--PVRKMTIGNMSQ--KISQEEGTRTSSYKLQPNK-SKNLGQKAAQ-EDMV
SPL--LLPMLLLRPQEKPSDLVFSQELILESNSESSN-LYLERQWMSLEEQLATSAAQLR
LNPHLARCHSMARHVARLVRVLARPQQHGLLLAGAQGTGRRTAITLAAGICQTRLFRLPC
-GSEEAILRCLREVSWHAGMLGQPVALLVPKGVDLTTFHHLLALATSGSFPDLYTEADLE
NIEGHL-PRDSLSVKQNIKKEILWQRFCHQVRSHLHM-FILIGD--DQARKQLPSTLFLR
LLQLAIACTDRYEPWDQDSLVAVAQHHLKGA-ESPPLDNDSLRFPDIQASVPSVAKAMAL
IHLSAASYQGHLCPELSLVTPKTFLDFLDTFVLQRQWMTLHIKNRAQRIQNALENLKMLI
EKHSAHTTLVFNLEEQLKGSHKS------------LGRLNHQLDQSKILYKRQLTECRQQ
ENLIENLTKQRDALRAQYEAFLEQMGKAFLGPLSQLQVADFEEIRSYRAPPESVVQVTDA
LCDLFHRETGWASAKQLLCSEDFYQELVFFPKEKMTDAEIIKLNLALKAPGMSDADLRAV
SIPIASLAAWLWAVLCYGLAQRRGLPTGLLLRQVEATLAREQARLGQYEFQAQEILEHSL
ALSKNLENAQTSHKRVVENLGQAQCGKHHKWPVEAALLTPMHSWTTELQKLKGHSSTVLG
DTLLCSAAINYLGPFPPVRRQELLDKWLALCRGCQ---EPLGPDDVAQALKQMQKSVARL
-PKNPLLSIRSPFSLVSLLSSESEQFQWDRDMKPQAKSARLAALLLRSCTHYFSCRWPLL
LDPGNEALIWLKPLPLEEAGRLATSPTNGTGKGFK----RNKKESKEENMED-EDDDSDE
CDKTKEQKAEER-RIKETKEEKEGQQEQE----------------------EKEQQDEEE
TQSSPAPDLQVFSGASPEL--GPRLQEAAAHGLPVLLTNME--LGLDCPELQWLLQREQL
SPPQVQPGFCLYLSTTVPLNALEK----VLGCELLKGLNVLDLGVNTEILEERMLREILC
TERPELETHWWDLTVRFLDSWEAAGAVEERLLTMLLLQ--GPRRQKPDKFLRDVVRAQAE
LCQLHAHLEDLEELKLKEVALWAPYRRVVWHGMTIIKALSSLQNLLPLFRLSPEDCLAAT
KRALHSIKG-EIHQREEVTCRLLQLKRQLTHQLLGTTMATLGLTRVPLVGVLGALALLRV
ARKAPELERLALWPGLAVSPSTGCEKPVPRVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 4994)

AWLGLRTWHECEMLEVLPPFAGLCAS
LAGHASVWQAYLSLSSSVLGPAPG--PGAHPLSLLQKLILWRVLRPECLVSTLATFTTSL
LGRPLDENLSAHTIPIEHTQATQPILILLPPPGHPTATLHHLTVIQKLAARHKQ--GKKH
LKVIALGSETWDPVSIVISSLHKAMLRGEWLVLENCHRWLL--GLYPELGPELELGSHGL
SPQVSDLELELLFAQQANGNVAAVHRDFRLWLTVSAEATASLPAVLTQHSMPVFWDQSLE
LGHVLVDSMELVQQGLSVQP-PSRVLPLLLLHGLLLHRQLYGMKLQAHRGHWSQATLTHV
LQIQDQLWASLSNPSVAMRELAASVFYGGPVGDDKDREVLVSLTRACLSSSSGNGAQPHT
PQYLLATLMPSPELKELDALEECKAQMHLLPTPPEPRICGLSAGSQTWLLRRQSRAILSA
LQRCSPTWVPAARGTS---RRAERRLRQRLAQAKRRLESLQAQLTETTRQEES---GVGF
GELGLSAPLPVEGFLKTEVLELSQLVGALQRDLDCLLQQLKGAPLCAARRCAEVAQALWT
GRLPPPWRPHAPAGPQPPWHWLRQLSRRGQLLLRYLGVG----TQVPERIFHLSAFCHPR
RLLLSLRWEATFAV------VAPTNFLACQASSSC-----QLPHKRQELI-SPLHFQVAN
GPHPTVPEMGL-LLIGLQLHNAKWDPVAGALQDSSSSQPSPLPPVSVSAQAPGANDLPPR
GGLAVYSCPVYLEGPLGTTRLHRRKVLMHLPLPTKLSPATCIQRRVHVCSPPLS

------------------------------------------------------------
------------------------------------------------------------
-----VSDEEASSKALES-RHSVGVL-DKAEQRQACQGKKRQSLKAVTWSKRPTVLELLV
AELQTLFSKVLQDGSPAAWNYLHAVLGLLPPYRALLVGRLDLLPFLERLYHWAPWVQAQL
HLDLLDAIDQAFPRDTSLLEGTSHVDCYPQKKRFHHGTPHPACPFVQAQWEGQQVEDDLA
TWLRPLTLPELQHSLGIVGAEVAVEETQWLHGLRLVPLALATDIPVQYESSDPDNAEEEP
VGRTETRSQLDLEVPEEKTLQKRSTGFLPQISLLGSQIMAVMKTERYLKKIHFLYLNVAP
SRYFTPYSLMVVPANKVNPEYYIFSPFGILHVHPVEGSEAMTLGTWHRHSVLWQQLQLIP
FFKYCLLRKALASWKKSVKLQRLHQHRSFLEKHLLLAVPHFGAGLLHISRLLQELHTVTW
LPHEADQCYELLDLRRALAKENHKALRLLYRCLRLCTSILHLIHEDTYQMQQGLQQRLKN
CKKIRTDQTSVYLQKAQCQQLEQRLKQAEAWLLQMGQLARLVDYMICQNLMSIIEEEITS
FVANILQAPRQKPFLSAQLVFDSSGQLSQEPCIENMIQTLTVGLRSTKASALKVMQSTDL
KTFWESLY--IEDEDEEDYSDSDFMMPKFQGQPSDAVDVFCGPNIGLVWPWKSRTVTEAL
EVHGHRLRGQYSPLDYKQLQEDLDNSPQIQQALAVQQALLEDMLQEVQEFCRDYHWMTGI
YEFLQAWGCQKLESMRGYPIKNYVMLVTRLNAWQAQVSRIPMELITRGL-LLLSCRNIQA
EMESKLVNIRKDILEQVQNECQSRSQQLITELTGFMKAFQTINSDIHSIAWCSQKLNEAN
ERYAELEEQMEYTRSLYELIRNHFGLFSAENEALDISVRRHLLCPTRC-SSPH-PPALLD
HPLPAPQLMDTWESFQYEKSQASEFLLSKRHAIVPKLQQLMATALAELEGMIEKALSGPF
MDPAQEQRNTERQLISLERQYQNTVSSLSDLHHAYTAFTGDESPVPLPVCGTRPI

PF08393 // ENSGT00910000144015_1_Domain_0 (1136, 1293)

VQQQH
IWHLYRVISENISEWKCMAFAKFNLALAQEKTDGWLTEAARVSATLGLHSPVLQRCMRML
EEFRSLLPLLTKLGSLQVQNLNCQALLRALGLSSFYSIELLTVGQLLSCPLLEFTDR--I
NQIWRTENIRNHAHEALLRLRRAWEARQLRLL

ENSGT00910000144015_1_Linker_0_1 (1293, 1326)

NFILHVPYESPVSERSKRQ---ASRSPQ
WQVVG

PF08393 // ENSGT00910000144015_1_Domain_1 (1326, 1602)

KDSGTFILSDYSSLQDSIHESLQVLFKILAIQKSGDLNRIALEWVTIMHGLS---
ALLQVWVTFQQKWIFLNKVLHEMKIQFPSPELSTRFEATDAQYRTLMQISVADPLVLSLI
-VPSAKRNPLFQGQQLQQLLQEGSMDLEGIIMALESVLYAVRAHFPRLFFLSDSELVALL
AAPLESCEAQLWARRCFPHVHALSFESSETA-KD-TDDPES----SPSIQTQVAVLAVFG
AGGEEMKLRGSLLLHPDLPKWLASLEESLRLALVHNLQDCVAARLAL--SLDKAFKQENH
LPQESQLP----PKMYVQHWLDLVQAFPWQCVLVAEEVAWRAGMEEALLEGRTLAMVPMH
VRKLEVLVHFLRAQRASQGEQPLLSVRQTSLLSALLVMAVTHRDIAQLLQEHQVSGLTDF
HWVRQLKYHLGSPHTAPQSPLKGLKTVVS-TETFLSPAACWIDVLGRSFLYNYEYLGPRL
GSLPSLLPERPALVLLLALEEVACGTLLGPSGVGKGAIVKSLAQALGRQLVVMPCLPQMQ
ARSLSSYLNGALQGGAWLLLEAAQHLPLGLLSALGQRLAKLHHLYAPLYQEASRSTSTID
-------PTHPWLLGSSFFERHHVDMRLGYGCLLTLRALSPAMPANLRQLLRPVALTL-P
DLQQVAELTLLGAGIRDASRAATRLSKFFSLECELVSGPLPCRLPLLRKVLEDTIQALNL
TKKDPESEQPRSLATMEEATLLRTLLRSPLFSLLEGPHLQDLQKLLCGLFPTASQVLAEP
VTPRLRKSLLVEELRQGGLHPSPDILGSLDQLSQALGQASGILLLGPAGSGKTTCWHSLF
KIQNRRPHLALS--------AQPIPAH-RYKLEL--------------------------
--------------VAQVLRWT---------WVLGLKMRSNSQPLLSFP-------P---
------------------------------------------------------------
----PPLFFY---------------------------------------------WGSFP
--GHEDLSYSDSKCIVARSIKASKTSSL-HQNQIDSDAVPSKRREHLLAISSFLFAVIWG
FGAH--------------LPSSRL-WPLYDTFLRDSISCLSNYSELPPSDSVFDLHVCPE
DGTLAPFTGQYLGSRIKGIQGTFYPSPQTEGLLYVVDLLLSEGHPVLLAGEAATGKTTFV
EVLVEPQHPYINSPIHPAVSTTHLRLLLSREVQGQSQA-SPWTGRHPDSKGFLLFLLEDL
HLAASDPEKSCQPLLETLRQAIDGTVYTHSTLELQTLQPGVNFLATATVPGFYERPLCPR
LSRLFTVLALGSVTQAMLLSRHMPSMQAWLERFPSVERESVLARALVRASLEAWEAVGKC
FMPSPLRPHYRFSMHSVSQLLGSLQLLPVRVGSRGFVDCLNHQEHLRRVSGLRGTRLMIM
MATRNIVRLWLHEAQRTFCDRLDSPRERSFCARLLLEVAQNVFCCGPAPQSLGKGYEEEE
-------EEEKVPEVESEGELAQWEDL-----SNSGSETEEEEAPYDLPVTTGSPSNDS-
-APPA---A--PVRKMTMGNMSQ--KTTQEEGTRTSSYKLQPNK-SKNLYQKAAQ-EDMV
SPL--LLPMLLLRPQERPSDLVFSQELILESNSESSN-LYLERQWVSLEEQLATSAAQLR
LSPHLARCHSMAQHVARLVRVLARPQQHGLLLAGAQGTGRCTAVTLAAGICQTRLFHLPC
-GSEEAVLRCLREVSWHAGTLGQPVALLVPKGVDLTTFHRLLALATSGSFPDLYTEADLE
NIEGHL-PRDSISVKQNIKKEILWQRFCQQVRSHLHM-FILIGD--DQAHKQLPSTLFLR
LLQLAIACTDRYEPWDQDSLVTVAQHHLKGV-QSPPLDNDSLRFPDIQASVPSVAKAMAL
IHLSAASYQGHLCPELPLVTPKTFLDFLDTFVLQRQWMTLHIKNRAQRIQNALENLKMLI
ERHSAHTTLVFNLEEQLKGSHKS------------LGRLTHQIDQSKILYKRQLIECRQQ
ENLIENLTKQRDALRAQYEAFLEQMGKAFLGPLSQLQVADFEEIRSYRAPPESVVQVTDA
LCDLFHRETGWASAKQLLCSEDFYQELVFFPKEKMTDAEMIKLNLALKAPGMSDADLRAV
SIPIASLAAWLWAVLCYGLAQRRGLPTGLLLRQVEATLAREQARLGQYQFQAQELLEHSL
ALSKNLENAQTSHKRVVENLGQAQCGKHHKWPVEAALLTPMHSWTTELQKLKGHSSTVLG
DALLCSAAINYLGPFPPVRRQELLDKWLALCRGCQ---EPLGPDDVAQALKQMQKSVATL
-PKNPLLSTRSPFSLVSLLSSESEQFQWDRDMKPQAKSARLAALLLRSRTHYFSCRWPLL
LDPGNEALIWLKPLPLEEAGRLANGPTNGTGKGFK----RNKRESKEENMED-EDDDSDE
CDKTKEQKAEEK-RIKETKEKKEGQQEQE----------------------EKEQQDEEG
PQSPPPLDLQVFSGASPEL--GPQLQEAAAHGLPVLLTNME--LGLDCPELQWLLQREQL
SPPQVQPGFCLYLSTAVPLNALEK----VLGCELLKGLNVLDLGVNTEILEERMLREILC
TERPELETHWWDLTVRFLDSWEAAVVVEERLLLMLLLQ--GPWRQRPA---------QVE
LCRLHAHLEDLEELRLKEVAVWAPYRRVVWHGMTIIKALSSLQNLLPLFHMSPEDCLAAT
KRALNSIKG-EIHRREEVTCRLLQLKRQLTHQLLGSTVATLGLTRVPLVGVLGALALLRV
ARKAPELERLALWPGLAVSPSIGCEKPAPGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 4994)

AWLGLRTWHECEMLEVLPPFAGLCAS
LAGHASVWQAYLSLSSSVLGPAPG--PGAHPLSLLQKLILWRVLRPECLVSTLATFTTSL
LGRPLDENLSAHTIPFEHTQATQPILILLPPPGHPTATLHHLTVIQKLAARHQQ--GKKH
LKVIALGSETWDPVSIVISSLRKAMLRGEWLVLENCHLMP----HWPKELLQPLLGLLDG
AKEVSDLDLELLFAQQANRNVAAVHRDFRLWLTVSAEATASLPAVLTQHSMPVFWDQSLE
LGHVLVDSVELVQQGLSVQP-PSRVLPLLLLHGLLLHRQLYGMKLQAHRGHWSQATLTHV
LQIQDQLCASLSNPSVAMRELAASVFYGGPVGDDKDREVLISLTRACLSSSSGNGAQPHT
PQYLLATLMPSPELKELDALEECKGQMHLLPTPPEPRICGLSAGSQTWLLRRQSRAILSA
LQRCSPTWVPAARGTS---RRAERRLRQRLAQAKRRLESLQAQLTEIMRQEES---GVGF
GELGLSAPLPLEGFLKTEVLELSQLVGALQRDLDCLLQQLKGAPPCAARRCAAVAQALWT
GRLPAPWRPHAPAGPQPPWHWLRQLSRRGQLLLRYLGVG----TQVPERIFHLSAFCHPR
RLLLSLRWEATFAV------VAPTNFPACQTSSSC-----QLPHKRQELI-SPLHFQVAN
SPHPTVPEMGL-LLIGLQLHNAKWDPVAGALQDSSSSQPSPLPPVSVSAQAPAANDLPPR
GGLAVYSCPVYLEGPLGTTRLHRRKVLMHLPLPTKLSPATCIQRRVHVCSAPLS

------------------------------------------------------------
--------------------------------------------------------MVPE
ERRVGLSSDETSSDSLKSW-HSICVL-DSKEQPLACQQKQRQFVKPVTESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEVEP
VGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERVQN
CDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITS
FVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKDEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVRGCRLRGQYFPHNYKQLEEDLDNNPKIQQALNIQQVLLEGVLCKVQEFCREHHWITGI
YEFLQSWGPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPIELLTKGGLLLLSCHDVQA
EMESKLNSIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGESPIPPCPPPPQPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIMPKLQQLMAAALAELEGLLAKALSGPF
MDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL
GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVSFRSCPTG-EKNTDDWES----SPNTQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTIAS-SEPSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTID
-------PTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNV
TKEEPKCQKPRSLAAIEEAA----LLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEP
MTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRLQHRTVAELNHMA
EVLVPATLRFLTCQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAP-
--GPEDLSYSDPVAQ---SFRSSKSSFL-NRSQVDSDDVPDKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2783)

QTERLLYVVDLLLSGGQPVLLAGEAATGKSAFV
EVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQA-SPQPGHHQDSKPSLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNC
FMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQESE
E---E-EEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVARVSNSRDPS
LTPSI---G--PVSRGMKESISH--KIRQEKGTRASNYRLQVRRSFKTWWQKKPQ-MDLI
SPL--LLPVLLLHPQEKPSDLVFSQELILGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPS
-GSEEAILQCLRDASWHAGMLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
RIGEHL-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALAKVAQHHLEGA-QSVPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLI
KEHGTHANLIFDLEQQLKDSGKS------------LSMFQQQLEQSKLLYKQQLEECRHQ
ENLIENLARQRDALQAQREAFLEQMS

PF12777 // ENSGT00910000144015_1_Domain_7 (3447, 3686)

KAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNL
ALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFG
DTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQ---EALGPDDVAQALKRKQKSVSIP
-PKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNEALIWLDPLPLEENRSFAPALTEGRGKGLM----RNQKRESK-TDMKEEDDESEE
SNEAEDQTKEQKAEERKNEQE---------K------EQEENEEKEEEKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCEELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
REYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNIVRAQGK
LCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQA
TGKASELERLALWPGLAASPSTVHSKPVSDVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSSAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQ--GQKQ
LQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQVLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHT
PQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSA
LQRSSPVWVPESRRGA---QLAERRLRQRLVQVNRRLESLQDLLTHVIRQDES---DAPW
SVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGSVSS-----QLQYKRLEMNSNPLHFRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAP
ADLTVYSCPVYMGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

------------------------------------------------------------
---MIPHPQTS-PSSLPTPSTCRRPGETQQPKAWNWHLNPELWARSVRQQLNTCLRFILE
DS-------KPSFSTLESG-LTECSC-SPQGHSWDCIKKQ-ELLKAVVESEQRTSLELLL
SELRSLLSAVLQDGSCEAWRYLYAVLGLLPPYREMLVGQLDLLPLLEQLYCCAPKVQSQL
HLDLLDAIDKVFPPDRSLLHSSSHVDCHPWTKRSHRRPPCWPCPFVKALWSGQQK-RELA
TWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLPLALATDIPVQYESGDADYEEGES
SGR---KSQLASESPEEKAFKKKS----SKTSLLTSRMKSLLKIDRYQRKIHFLYLNVAP
DRYFKPYNLIVVPPNKVNPEHYIFSPFGIMHVHPVEGSETMTLGTWHRNSALWHELQNIP
FFKNCLLRKALTCWKKNVRLYGLHRIQTLLKNNLLLAIPHFGAGMLHISRLLQEFRSVSW
LPKEPDKSYELLDLQRTLAKENHKALRMFCRFLNFCTSVLQLVHEDTYQMQQGLQERVKN
WNRIRKGQGSLYLQRVLCRHLEKKLKQAETWLLKLGKFARLIDYIICQNLISILENEITS
FVANTLQAPRQNPFLLSQLVFDDNGQLSPMPRVETIIQSLTNGLQSIKTSALKVLQSTDR
RTSRDPLYSE---DDKDQDSNVEFQMPQFHGQPSDAVQLFCGPNVGFVWPWKSQAITDVL
EVRGHRLRGQYLHPNYNHVQEDLDNSAKIQQALAVQQALLEDMLQEVQEFCNEHKWVECI
YKFLKAWDPQKLEDLRGSPIKDYVILVGQMEEWQERVSNMPVQLLTKGKLLLLSGHDVQA
ELESKLNSMRKSIFAQVQSECWSRNQRLMTELTDYLRVFQTISSDIHAIAQCSQKLNEAN
EQYSQLEERVEYVRSLHELIRNHCGLFIAENETLDIA-----------------------
-------LLDVWESFQFERSQASEFLLSKRHSIVPKLQQMMAVALAELEGLLSKALSGPF
MDPSQEQRSTEHQLSVLEHQFSKTLNNFNDLHYAYITFTGDDSTMSPPTCGSRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

QQQR
IWRLYRIITENFSEWKCMAFTKFSLSMAREKTDAWLTEAARLSTTLGLHSPVIQRCMRLL
EEFRNYLPLLNKLGTLQLQNFNCQSLLRMLGLSGLQSFDLLTLGQLLNCPLLEFADR--I
NQVWQYNKERIHAQEILQQMQQYWEGRQLRLLNFILHVPYKPPASERSKKQ---AFRSPQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGELHKMALEWMNIMHGLG---
ALLEVWVAFQQKWIFLNKVLHEMEIQFPDAELNARFKAMDDQYRTLMRISVADPMVLSLI
-VPNSKRSPYFQGQHLQQLLKAGSVELEAIVMALADVLYGVCAHFPRLFFLSDSELVALL
AAPLEACEAQSWAQRCFPHIKAVNFRSAPHE-EKSKNDQES----SSGTQGQVETIAVLG
AFGEKVKLQDPLPLQPDLPKWLASLEKCLRFVIVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLVKALEA---
LPQQRQAP----MQLYVQHWLDAIQVFPWQCILVAEEVVWRAEMEEVLFEWGTLRTVSIH
VHKLEVLVQFIRAQRSSQGEQPLPSVLQTSLFSTLLVMTVTHRDIAQLLEKHQVRDLTDF
HWVRQLKYHLGSSHLNSNSPLQCLKTIAS-AEPSLSPAACWIDVLGRSFI

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPKL
GPLPSLMHEREVLVLLLALEEVACGTLLGRDGLGKTEMVTSLAWTLGRQLVMMPCLPQIE
FRCLSNYLNGALQGGAWLLLENIHQLPASLLSALGQRLDELHHLYAPLCQKASKNISTIN
-------PTKAPFVGAGFFEKHDVSMRLGYGCFLTLNVLRRDVPANLHLLLRPVAFAL-P
DLQRVAELNLLCAGVQDASRMAIRLSRLFSLERELVSGTLPCRLPLLKQVLKDTIQTLNA
TKEENNSQQPHNSVAPEEAALLHALLHSPLFSILDGFRLQKLKELLCGIFPNASHVLAEP
VTPRLMRSVVVEELQQLGLLPTPNTLMSLEQLSQALSQASGILLLGPAGSGKSTCWKSLL
KIQNRLAAMEQT----STQGFQSVEIAHLYPSVLSTQEFLGWSEGPSWHYGIFPKLLHAA
PHCNSMDSEEQLKEFTGIQQWIVCDGAPNSTWIDSITCLLSDPPQLSLPNGQQIARPLST
FFLMEVAEASGMSPTVVGRCALVWCCGEQTWQCMLNVLMASLPHEYHLLQGTITELKKLA
EVLVPAVLRFLTRIGASSLLQVH-GHQTVCQGVAEVTSLARILRALLDPHLRLYEEEKT-
----EDFSGSDLATQ---SFRSSKS-----RVKPDSDNVNKRQRKHLLAISSFLFATVWG
FGGH--------------IPS-RH-WPLFDNFMRNSISSLSNYPEPPPSALVFDLRVNIE
DGTLVPFTGHYLSSCIRGSLGTFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2783)

SQTERLLYVVDLLLSNGQPVLLAGEIATGKSAFV
EVLVEPNHPSIHSPIHSALSSTHFRHLLSRGIPGQTQA-GTYLGHHQESKGSLLFLMEDL
HLAASDPDKICQPVLETLRQAMEGTIYARNTLELQTLQPTVNFLATATVPGYSERPLCPR
LFRLFTVLALDNMTQDTLLSRHVPGIQAWLERFPSVEREHTLARALVRASMEAWEAVCNC
FMPSPLHPHYRFSLHSVSHILG

ENSGT00910000144015_1_Linker_5_6 (2783, 3072)

SLQLLPTRTGSRGFVNTFHHQEHLRRVSGLRGTRLTIM
MSVRILVRLWLHEAQRTFCDRLDSDRERSHCANLLLQVAKSVFCCGPQSQPMVKDYEE-E
------VEEEKVPEVESEGEIAQWEDL-----SNSDSESEEEVDPYGIHASTGSFLGDSS
LAPFPI--K--SVNKENAESVSQ--MAEQEEDIRASRGELQSQTSEKSVWQRASQ-MDFS
LPL--LMPVLLLYPQENLSNLVFSLELTLGSNFENPN-FYLERQWENLEKQLAASAVRLK
LNPHLAQCRMM

PF12780 // ENSGT00910000144015_1_Domain_6 (3072, 3331)

TQHVARLVRVLARPRQHGLLLSVARGTGRHTAIRLASSICQARLFRLPS
-ESDQAISQCLRDASWYAGVLNQPVALLVPDNVNVALFHQLVALATSGSFPDQYTDADLD
KIEEHL-PKENYMVKLIMKKDTILHRFYQQVCSNLHM-FFLMRD--DQAPKQLPSTLFLR
LLQLATASVDRYEPWDQDSLVRIAQCHLENV-QSLPLDDGSLKCPDIKALIPNVAKIMAL
IHLSSACYHQHLCPALPLVTPKTFLDFLDM

ENSGT00910000144015_1_Linker_6_7 (3331, 3449)

FLLQQQQMILKMRMKAWRFNSALKTLRMMV
ERHSTQTNHLTDLEKQLKGSYKN------------VGVYQSQLEQSKLLFKLKMSECQHQ
ESLIENLIRQQDALQAQQEAFLEQMGKA

PF12777 // ENSGT00910000144015_1_Domain_7 (3449, 3687)

FLGPLNQLKVADFEEIRSYRAPPEAVVQVTNA
LCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKLTDAELIKLNKALKAPGLSDKALRSV
SIPVANLAAWLWAVLHYGMAQRRGLPTGLLLRQVEAALAREQARLGQLQFQIDDLLEEIL
SLTKKLEEAQASHNLAMETLNQAQGGQFHKWPIRSLLLTPIHTWTEQLQKLKNHCKTVFG
DALLCSAAIVYLGPFPPQRRQELLEKWLSLCQGFE---EALEPDDVAQAMKQ--KSVRVT
-PKNPLVPTCSPFRILSLLSCGPEHHQWDRDKRPQAKSARLLGLLLRSHIHFNSCRWPLL
LDPSNQALIWLNPLPLKEDKNTLL-YLSIPAEHRV----TNQDSEEETEDEDDNGNDEED
RNETNNQNNGEEV-------------------KEQEEQETEKEKNET---ESSNSSTLSE
TP-SLPPCLTMLSGADPEL--GPQLLEAAANGLPVLLTNME--LSLGCQELHRLLSRENL
SPPHVQPGFCLYLSTTLPIHALER----VLGCELLKGLNVLDLGLNMDILEEQMLHEILC
RERPELETHWQDLQIRAVDISEAVTTAEERLLVTLLLQ--NQKRQKPSKFLRAMVRTQAK
ICQLNAQKEEIEEQKLEDMILWAPYRQIACHGMAIVEALSPLQNLLPFFCMKLENWMAAT
RQALDSMKPHDSYHGEDLASHLLQLKINLTRQLLTSTVAALGLTQAPLVGALGALALLQV
TKKTPKLERLAFWPGLSASPSIGHNTQVPGVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5028)

AWLGLRAWQECGMLELLPPFAGLRAS
LAGHSSVWQDYLSLSSTVLGPSPG--PNSEPLSLLQKLILWRVLRPDCLEGTLADLTTSL
LGRPLDENLSNPTMIFEQNWATQPILILLPPPGHPTAILHPLTVIRKLAANHEK--TQKH
LHVIALGSEDWDPVSTIVNTLCQAMLQGHWLVLDNCHLMS----HWPRELLQPLLRLLDG
ARVVSDSEL---LVEPESSNVATVHRDFRLWLIVSTEASSSLPGVLTWLSMPVFWDQSLE
LGRILIDSVG-SQQGLCMQP-LTQTLPLLLLHGLLLHRQLYGIKLQAHRGRWSQVTLTKV
LQIQKHLWASLSNPSAALLELAASVFYGASLKDPGDREALISLTGACLNPSNTSWVRY-T
PQYLLATLMPSPELGELDAMTECKARMHLLPTPAEPRACGLNEGPKSWRLRRQSRALLNM
LQQCSSTWVPSASGRN--AQHKERRLRQRLVQAKKRLVALQDLLTN-G--SCSGQSAIPW
AVLGPNARRPLEGFLETEVLELRQLVGILQRDLDCLLQQLKGKTPCTSSRCVAVAHALWA
GRLPRPWRSHAPAGPQLPWHWLRHLSRRGNLLIRYLDSGTSENANEPERIFHLSAFRHPR
RLLLALRWEAILES-----SEPCPNPTGTQGSGSG-----RVPPKRQELNNHPLHIRVEN
GPNPKVPKMGL-LLIGLQLQHAEWDKMDGALQDSFSSQPSPLPPVSVSTQARGASDARDS
GGLDVYSCPVYMTGPLGTTKLHSKNILMHLPLPTRLSPDTCIQRRVHVSSPTLS

------------------------------------------------------------
--------------------------------------------------------MVPE
EKRVGLSSDETSSDALKSW-HSICVL-DSKEEPLARQQKQRQFVKPATESEQPTVLELLL
AELRTLFSAVLQDSSPAAWHYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAINQAFPPDSSLLDSASHADCCPQKQRLHHRPPCPACPFVQARWSRQQVKEELA
TWLRPLTLPELQHCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRKETRSQLDYEVPREKTLQKSSTGFSPETSFLGSQVMTALKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNAEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPRELDRCYELLDLQKALAKEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CNRIRAGQGSIYLQRVQRKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILEEQITS
FVANILQAPRQKPFLSSQLVFDDHDQLSHVPCVENMIQILTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKTEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVHGYRLRGQYFPRNYKQLEEDLNNNPQIQQALNIQQVLLEGVLWEVQEFCREHHWITGI
YEFLQSWVPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPVELLTKGKLLLLSCRDVQT
EMESKLDSIRKDILAQVQNECWSLSQQLMTELTNFMHVFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFRESPIPPRPPPPRPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIIPKLQQLMAAALAELEGLLGKALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSELHHAYVIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTEGWLTEAARMSTTLGLNSPVLQHCMRIL
GEFRSYLPLLAKLGSLQPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIQQLQRYWEVRQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIQKSGDLNKIALEWMAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVVDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVRFKSCPTG-EKNMDDWES----SPNAQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWINLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFLRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTTS-SEHSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHSLYAPLYQEASRNTSTID
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIQTLNV
AKEEPKCQQPRSLAAIEEAALLHALLHSSLFSVLNGLHLHNLRGLLCALFPSASQVLAEA
MTYKLMKALVVEELQQVGLHPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEGT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESMGIQHWIICDGASSAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADATGMSPTVVGCSALVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNHMA
EVLVPATFRFLARQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDPHLRLKEEKAP-
--GPEDLSCSDSVAQ---SFRSSKSSFL-NQSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2781)

QTERLLYVVDLLLSRGQPVLLAGEAATGKSVFV
EVLVEPHHPYIYSPIHPAFSSTHLRLLLSRGIQGQTQA-SPQPGHHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERERALARALVRASVEAWEAVCNC
FMPSPLHPHYHFSPHSVSHLLSNLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTRLTIM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCGKLLLVVAQSVFCCGPGPQNLGKDHEEDE
------EEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVATGSNSSDPS
LTPSI---G--PVSRGMRESISH--KIRQEKGTRASNYRLQVRRSFKTWWQKAPQ-MDLV
SPL--LLPVLLLHPQEKPSDVVFSQELTLGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQTHFFHLPS
-GSEEDILQCLRDASWRAGLLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
RIEEHF-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-RSLPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQIILKIKNKAQRVQNALENLRMLI
KEHGTHANLISDLEQQLKASSKS------------LSMFQQQLEQSKLLYKQQL

PF12777 // ENSGT00910000144015_1_Domain_7 (3415, 3687)

EECRHQ
ENLIEDLAKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKITDSQLIKLHLILKAPGMSDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLIREQARLGYYQFQAQETLENNL
ALAKMVEDAQASHNCVAKTLSQAQHGQYHKWPMKAALLMPMHAWTIQLQKLKGRCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKNPLLATHSPFNILSLLSSASEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALMWLDPLPLAENRCLAPAPTEGRGKGLM----RNQNTESK-MDMKEEDDDSED
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RECPELETRWQNLKIRALDTCKAVEAAEERLLTMLLFQ--NTKREKPAKFLRNMVRAQGK
LCQLRAHCEELEGQKLQEMVSWAPYRPVVWHGIAMVKALSQLQNLLPLFRMSPEKWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVSGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMGAPTMPFKHSRATQPMLILLPLPGHPTATLHPLTVIENLAAKYQQ--GQKH
LQVIALGSEVWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLGQPESSNVATVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALFSLTQACLSPSSRNWVQPHT
PQSLLATLMPLPELREPDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRVLLSA
LQRSSPVWVPESRGGA---QLAERRLRQRLVQVNRRLESLQDLLTNLVRQDES---GAPR
SVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADANSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGAVSS-----PLPYKRLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPPP
ADLTVYSCPVYMGGPLGNTKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

------------------------------------------------------------
-----LEPETI-SHPYPAPTGLGHTGETQQPKVWNWHLAPELWARSVRQQLNTCLRFTLE
ER-------NLSFDTLESG-LTECSC-NSQEHTWDCLKKQ-ERLKAVVESEQRTSLELLL
SELRSLLSAVLQDGSSEAWRYLHAVLGLLSPYREMLTGQLDLLPLLEQLYCWAPKVQSEL
RLDLLDAIDKAFPPDSSLLSSSSHVDCRPWMKRSHRGPPYPVCPFVKARWGEKQK-KELG
TWLRPLTLPELQRCLGIVGAEVALEESQWLDSLSLLPLALATDIPVQYESSDADHKQEES
AGR---KSLLASEAPEEKAFRKKS----SKASLLRRQVKSLLRTDWYQKKIHFLYLNVVP
DR---PYNLIVVPPSKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHRNSTVWHELQRIP
FFKNCLLRKALTCWKKNVRFYGLHRIQTFLKGHLLLVVPHFGAGMLHISRLLREFQSVSW
LPKEPDKCYELQDLQKTIAKENHKALRTFCRFLNLCTSILQLVHEDTYQMQQGLQERVQN
WNRIRKGQGSIYLQRVLCRHLEKKLKLAETWLLKLGKFARLIDYMICQNLVSILEDEITS
FVANTMQAPRQNPFLLSQLVFDDNGQLSPMPCVETIIQTLNKGLQSIKTSALKVLQSTDL
RTSKDPLYSE---DDKDQDSNAEFLMPKFHGKPSDAVRLFCGPNVGFVWPWKSHAITDVL
EVRGHRLRGQYLPPNYNHVQEDLDNNARIQQALAVQQALLEDMLQEVQEFCNEQQWVEGI
YEFLTAWDPQKLEDLRGSPIKDYVVLVNQLKVWQKRVSNMPVQLLTKGKLLLLSGHNVQA
ELESKLDNLRKNILAQVQSECWSRNQQLMTELTDFLRVFQTINSDIHAIAQCSQKLNEAN
EQYSQLEERVEYVRSLHDLIRNHC--FIAENETLDIS-----------------------
-------LLDIWEAFQFERSQASEFLLSKRHAIVPKLQQLMAAALAELEGLLAKALSGPF
MDPSQEQRSTEHQLTALEHQFLNTYNNFNELRYAYTTFTGDESSMSPPASGNRPII

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

QQQR
IWRLYRMISENISEWKCMAFTKFSLLMAWEKTEAWLTEAARLSATLGMHNPVLQRCMRML
EEFRSYLPLLTKLGSLQFQNFNCQSLLRVLGLGSLQSLDLLTLGQLLNCPLLEFSDR--I
NQVWQYDKERIHAQESLQQMQQYWEGRQLRLLNFILHVPYKPPTSERSKRQ---AFRSPR
WELVGKDSGTFLLSDFSSLQDAIQNSLQALFKILAIQKSGELHKIALEWVTIMYGLG---
ALLEVWVAFQQKWIFLNKVLHEMKIQFPGAELNARFKVMDDQYRTLMRISVADPMVLSLI
-VPNAKRSPYFQGQHLQQLLKAGSVELETIIVALEDVLYGVCAHFPRLFFLSDSELVALL
AAPLETCEAQSWAQRCFPHIKAVNFRSNPID-EKSKNNKES----SSTAQIPEETIAVLG
AYGEKVKLQGPLPLHPDLPKWLASLEKCLRFVIVNLLQN

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLVNALKA---
LPQQRQVP----MQLHVQHWLDAVQVFPWQCILVAEEVVWCAEMEEALFDRGTMRTTRIH
VHKLEVLVQFIRAQRSSQGEQPLPSVLQTSLFSILLVMAVTHRDIAQLLEKHHVSDLTDF
HWVRQLKYRLGSSHLKPKSPLQCLKTIAS-ADPSLSPAVCWIDVLGRSFI

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPKL
GPLPSLIHERQVLLLLLALEEVACGTLLGRNGLGKTEMVNSLAWTLGRQLVMMPCLPQIE
FRCLSNYLNGALQGGAWLLLENAHQLPPSLLSALGQRLDELHHLYAPLYQKASKNISTIN
-------PTRPLFLGSGFFEKHHVSMRLGYGCFLTFRSLSLDVPANLHLLLRPVALAL-P
DLQRVAELNLLGAGVRDASRMAARLSKLFSLERDLVSGTLPCRLPLLKQVLEDTIQTLNT
TEEENDSQQPHNLAAPEEAALLHALLHSPLFSILDGLRLQKLRELLCGIFPNASHVLAEP
VAHRLTRSVVVEELQQVGLLPTPNTLMSLEQLSQALSRASGILLLGPAGSGKSTCWKSLL
KIQNRLAAMEQT----STQGFQPVEIAHLYPSVLSSQEFLGWSEGPSWHYGIFPKLLHAA
SHGKSVDSEKQPEQFTGIQLWIVCDGAPNSTWLDSITCLLSDPPQLSLPNGQQIARPLST
FFLIEVAEAAGISPTVVGRCALVWCCGDQTWQYMLNVLMASLPNEYHLQQETIIELNHIA
EVLVPAVLRFLTRIGASSLLQVH-GHQTVCPGVAEVTSLALILRALLDPHLRLYEDEKPH
--DQEDFSGSDLATQ---SFKSSKS-----RSQSDSDNVNKKQRRHLLAISSFLFATIWG
FGAH--------------LPS-RH-WPLFDNFMKNSISSLSNYPEPPPSALVFDLHVNLE
DGTLVPFTGHYLSSCVKGNLGTFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2784)

SQTERLLYMVDLLLSNGHPVLLAGEIATGKSAFV
EVLVEPNHPSIHSPIHPALSSVHLRHLLSRGVHGQTQA-GF-FGFYQESKGSLLFLMEDL
HLAASDPEKSCQPVLETLRQAMEGTIYARNTLELQTLQHTVNFLATATVPGYSERPLCPR
LFRLFTVLALDNMTQDTLLSRHVPSIQAWLERFPSVEREQTLARALVRASVEAWEAVCNC
FMPSPLRPHYRFSLHSVSHILGS

ENSGT00910000144015_1_Linker_5_6 (2784, 3072)

LQLLPTRMGSRSFIDVFHHQEHLRRVSGLRGTRLTIM
MSMRIMVRLWLHEAQRTFCDRLDSEKERSHCAKLLLEVAQSVFCCGSEAQPLVKDCEE-E
------VEEEKVPEVESEGEIAQWEDL-----SNSDSESEDEEDAYGIQATTGSLLSDSS
AAPFSI--R--SVNKENTESVSQ--MAEQEEDIRDPSGKLQSGT-LKSEWQMVSQ-MDLS
LPL--LLPVLVLYPHEKPSDLVFSLELTLGSNFESTN-LYLERQWENLEKQLAASAVRLK
LNPHLAQCHMM

PF12780 // ENSGT00910000144015_1_Domain_6 (3072, 3331)

TQHVARLVRVLARPRQHGLLLSMARGTGRHTAVSLASSICQAHFFHLPS
-ESEEAIFQCLRDASWCAGILNQPVALLVPESVNVAILHRLVALATSGSFPDQYTEADLD
NIEEHL-PKENLVVKLIIKKDTILHRFYQQVCSNLHM-FFLMGD--DQAQKQLPSTLLLR
LLQLATACVDRYEPWDQASLVRIAQSHLENV-QNLPLDDGSLKCPDIKALIPNVAKIMAL
IHLSSAYYHQHLCPALPLVTPKTFLDFLDM

ENSGT00910000144015_1_Linker_6_7 (3331, 3452)

FLLLQQQMILKMRMRA-RIHSALKTLRLLV
ERQSTQTNLVTDLEKELKGSYKN------------IGMYQSQLDQVKQLYKQKMTECQHQ
ESLIENLVRQQCTLQAQQEAFLEQMGKAFLG

PF12777 // ENSGT00910000144015_1_Domain_7 (3452, 3687)

PLSKLQVADFEELRSYRAPPESVVQVTDA
LCELFHHETGWANAKQLLCTEDFYQELVFFPKEKLTDSELIKLNQALKAPGMRDAALRSV
SIPAANLAVWLLAVLRYGIAQRRGLPTGLLLRQVEATLAREQARLGQFQFQAHDLLQQTL
SLTKKLEEAHAFYSLIMENLNQAQCGKYHKWPMKSALLTPMHMWTQQLQKLKDHCKTVFG
DALLCSAAIVYLGPFPPQRRHELLEKWLSLCQGFE---EALEPDDVAQALKQ--KPARVP
-PKDPLVPTCTPFRIMKLLSSESEQHQWDRDRKPQAKSARFLGLLLQSHIYYNSCRWPLL
LDPSNQALIWLNPLPLKQNKWLAPPSKESRAKHRV----TNQDSEDETEDEGDDDD-DED
RNEANNQTKEQKTEENKS--EE----------KEKEEQETEKEKSET---ESSNSSPSSE
TQ-S-PPLLTVLSSADPEL--GPQLLQAAANGLPVLLTNME--LSLGCQELHGLLLRENL
SPPHVQPGFCLYLSTTLPIHALER----VLGRKLLKGLNVLDLGLNMEILEEQMLHEILC
RERPELETRWQDLKIRAVDTYEAVEAAEERLLMILQLQ--NPKRKKPSKFMREMVRTQAK
ICQLNAQREEIEEQKLEEMVLWAPYRQVACHGMAVIKALSPLENLLPFFFMNLEKWLAVT
RRALDSMKPHDSYHGEDLASHMLQLKIHLTRQLLSSTLAALGLTQAPLVGALGALALLQV
TKKTPKLERLALWPGLSASPNRGHNTQIPGVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGLRAWQECGALELLSPFTGLRAS
LAGHSIVWQDYLSLSSTVLGPAPG--PNSEPLSLFQKLILWRVLRPDCLAGVLADLTTSL
LGRPLDEDLGAPTMIFEHSQATQPILIVLPPPGHPTATLHPVTVIRKLAANHDK--TQKH
LHVIALGSEDWDPVSTIVNTLRQAMLQGHWLVLDNCHLMP----HWPRELLQSLLGLLDG
AKVASDSEL---LAEQESKNMSTVHSDFRLWLIVSTEASASLPGVLTHHSMTVFWDQSLE
LGRILIDSVD-SQQGLCRQP-LTQTLPLFLLHGLLLHRQLYGIKLQAHRGRWSQITLTNI
LQIQEYLRASLSNPSAALLDLAASVFYGGSLEDPEDREALISLTRACLNPRSMSWVQPHT
PQHLLATLMPSPELGKLDAMTECKARMRLLPTPAEPRVCGLNEGPKFWLLRRQSRALLNA
LQQCSPTWVPSAGGGS--AQRKERRLRQRLVQAKKRLVALQALLTN-R--TRSGQGVTPW
AVLGPTAHRPLEGFLETEVLELRQLVSILQRDLDCLLQQLKGETPCTSSRCAAVAHALWA
GRLPRPWRPHAPAGPQLPWQWLRQLSRRGHLLIRYLDSDTSENANEPERIFHLSAFRHPC
RLLLALRWEAVLES-----SVPSPNLPGNQGSGSG-----SLPPKRQELNNHPLHIRVEN
GPNPKVPEMGL-LLIGLQLQHAEWDQMDGALQDSFSSQPSPLPPVSVSTQALGAKAAPVS
GGLGVYSCPVYMTGPLGTTKLHSKNILMHLPLPTKLSPDTCIQRRVHVCSPTLS

------------------------------------------------------------
--------------------------------------------------------MVPE
ERRVGLSSDETSSDSLKSW-HSICVL-DSKEQPLACQQKQRQFVKPVTESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVRYESSDTDNAEGEP
VGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQKALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRTGQGSIYLQRVQRKQLEHKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITS
FVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKAEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGTL
EVRGYRLRGQYFPRNYKQLEEDLDNNPQIQQALNIQQVLLEGVLCEVREFCREHHWITGI
YEFLQSWGPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPIELLTKGRLLLLSCHDVQA
EMESKLNSIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGESPIPPCPPPPQPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIMPKLQQLMAAALAELEGLLAKALSGPF
MDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL
GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIRRLQRYWEVRQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVSFRSCPTG-EKNTDDWES----SPNTQTQVEALAVLG
AGGEEVKLQGPLLLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLAQGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLMNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTIAS-SEPSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTID
-------PTQPQLLGSSFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNV
TKEELKCQKPRSLAAIEEAALLHALLRSPLFSILNGLHLHNLQGLLCALFPSASQVLAEP
MTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESIGIQHWIICDGASNAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSALMASLPYEYHLQHRTVAELNHMA
EVLVPATLRFLTCQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAP-
--GPEDLSYSDPVAQ---SFRSSKSSFL-NRSQVDSDDVPNKCREHLLAVSSFLFAVIWG
FGAH--------------LPS-RF-WPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2783)

QTERLLYVVDLLLSGGQPVLLAGEAATGKSAFV
EVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQA-SPQPGHHQDSKPSLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNC
FMPSPLHPHYHFSLHSVSHLLSSLQLLPNRIGSRGFVDYPNHQEHLHRVSGLRGTCLTVM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQESE
E---E-EEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVARVSNSRDPS
LTPST---G--PVRRGMKESISH--KIRQEKGTGASNYRLQVRRSFKTWWQKKPQ-MDLI
SPL--LLPVLLLHPQEKPSDLVFSQELILGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPS
-GSEEAILQCLRDASWHAGMLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
RIGEHL-PRENPGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-QSVPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRIQHALENLRMLT
KEHGTHANLIFDLEQQLKDSGKS------------LSMFQQQLEQSKLLHKQQLEECRH

PF12777 // ENSGT00910000144015_1_Domain_7 (3420, 3687)

Q
ENLIENLARQRDALQAQQEAFLEQMSKAFLEPLSQLQMADFEEIRSYRAPPESVVRVTDA
MCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMNDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLTREQARLGYYQFQAQETLEHNL
ALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFG
DTLLCSAAIVYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKRKQKSVSVP
-PKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALIWLDPLPLEENRSFAPAPTEGRGKGLM----RNQKRESK-TDMKEEDDESEE
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKEEEKTESQGSKPACE
TQLPSLPYLSVLSGADPEL--GSQLQEAAASGLRVLLTNVE--LGLGCEELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----ALGCELLKGLNVLDLGLNMEILEEQMLHEILC
REYPDLETRWQDLKIRALDTCKAVEAAEERLLTMLLFQ--NPKREKPAKFLRNIVRAQGK
LCQLRAHCEELEGQKLQEMVSWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQA
TGKASELERLALWPGLAASPSTVHSKPVSDVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSSAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSI
LGRPLDENMYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQ--GQKQ
LQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQVLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHT
PQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSA
LQRSSPVWVPESRRGA---QLAERRLRQRLVQVNRRLESLHDLLTHVIRQDES---GAPW
SVLGPNARRPLEGVLETEALELSQLVGTLQGDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGSVSS-----QLQYKRLEMNSNPLHFRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAP
ADLTVYSCPVYMGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

MKPHQQICAPSLALRSEPGRPGEDRALGGWKGSLLGPAPASNQSLAVGGSAGPRKGPLLV
CLRLQFYPSSCPNPTDPAPSLSPSPPLSWQSKVWNWHLDPELWARSVRQQLNACLCFDME
ERKEQ-----------------------LEDHAWSCPKKAKELLRELVESEERVALELLL
AELQSLISAVLQDGSSEAWRYLYAVLGLLPPYRELLGGHLDLLPFLEQLYCWAPKVQSHL
QLDLLDAIDKVFPPDSSLLHRASHVDCHPQKKRFHRESPRPACPIVKARWGGQQE-KELD
TWLRPLTLPELQHCLGIVGAEVALEETQWLNSLSLLPLALATDIPVQYESNGADHMEEEP
AAG---KSQLGSEAPDEKDFKKRSYDFLSETSILSSQVKSILKAEKSVKKVHFFYLNVAP
DRHFRPYNLIVVPPNKVNPEHYVFSPFGILHVHPAEGSETMSLGTWHRHSVLWQELQSIP
FFKYCLLRKALTCWKKNAKLYGLLRIQTFLMNHLLLVVPHFGAGLLHISRLLQELHSVSW
LPKEPDQTYELLDLQKALAKENHKALQLLCRFLNLCTSILQLVHEDTYQMQQGLQERVQN
WNRIRKGQGSIYLQRVLGRQLEKKLKQAEIWLLKLGKFARLVEYMICQNVVSILEDEITS
FVANILQAPRQNPLLLSQLVFDENSHLSPVPCVENVIQTFTKSLQSIKTSALKVIQSVDL
RTTRDPVYSE---D-KEQDSNAELLMPKFHGKPSDAVHLFCGPNVGFVWPWKSHAITDVL
EVHGHRLRGQYLPPNYDKMKEDLDSSALIQQALTAQQALLKDMRQEVQEFCNSQQWVAVI
YEFLKTWGPQKLENMRGCPIKDYVVLVNQLKVWEDQVSKMPVQLLTKGKLLLLSCHDVQA
ELESKLNSTRKTILEHVQNECWNRNQQLMTELTDFLRFFQTINSDIHAISQCSQKLNEAN
EQYTQLEERVEYVRSLHELLRNHHGLFSAENEVMDIS-----------------------
-------LLDMWEAFRFERGQASEFLLSKRYAIVPKLQQLMAAALAELEGLLQKALSAPF
MDPSQEQRSTEYQLIALEHQFLKTVSHFTELHHAYTTFTGEESPMALPICGTRPIVQQ

PF08393 // ENSGT00910000144015_1_Domain_1 (1139, 1598)

QC
IWHLYRIISENFSEWKGMALAKFNLSMAREKTDAWLTEAAKLSTTLGLHSPVLQHCMHML
EEFRSYLPLLTKLSSLHLQSINCQSLLRVLGLSTLHSTEFLTLGQLLNCPLLEFADR--I
NQVWQYDKERIHAQETLQQMQQYWEARQLRLLNFILHVPYEPPASERSKKQ---VFRSPQ
WELVDEDSGTFLLSDYSSLQDAIQDSLQALFKILAIQKSGELHKMALEWMTIMYGLG---
ALLEVWVAFQQKWIFLNKVLHEMKIQFPSADLNARFKVMDDQYRTLMCISVADPMVLSLI
-VPNAKRSPYFQGQHLQQLLQGGSVELEAIIVALENVFYGVCARFPRLFFLSDSELVALL
AAPLETCEAQTWAQRCFPHIKAVNFKSSPDD-EKNEDDQES----SPSRQAPVEALAVLG
AGGEQVKLQGPLPLHPDLPKWLASLEKCLRLVLVNML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVATCFAQNPSLVEEFKK---
LPQQRQAS----LPLHVQHWLDSVQAFPWQCILVAEEVVWRAEMEEVLLEWGTLGMTSMH
IHKLEVLLQFIRTQRSSQDGHPLPSVRQTSLLSTLLVMAVTHRDVAQLLEKHQVSGLTDF
HWARQLKYHLGSSHLTPKSPLQSLKTIAS-AEPSLSPATCWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPKL
GPLPSLMHERQVLVLLLALEEVACGTLLGRDGLGKAETMNGLARALGRQLVTMPCLPQIE
SRCLSNYLNGALQGGAWLLLEAVHRLPSSLLSALGQRLAEVHRLYAPLYQKASQSTSTID
-------PTDPLFLGIGFFEKHHVSMRLGYGCFLTMRALSPAVPANLHMLLRPVALAL-P
DLQRVAELTLLGAGVRDASRMATRLSKLFSLECELVSGTLPCRLPLLKQILEGTIHMLNV
TKEEDTSQKPHNSAVKEEAALLHALLNSPLFSILDGLRLQKLQELLCGIFPSASQVLAEP
MTHRLMRSVVVEELQRVDLLPTPNMLISLEQLSQALSRASGILLLGPAGSGKTTCWNSLF
KIQNRLAAMEHT----STKGFQSVEITHLYPSALSSQELLGWLEGSSWHYGIFPKLLRAA
PQCKSTGVTDQSEELMGIQQWIVCDGASSCAWLDSITCLLCDPPQLSLPNGQQIARPLST
LLLMEVADAEGMSPTVVGQCGLVWCGGEQTWQCMLTVLMTSLPNEYHLQQRTIVELNRLA
EIMVPAVLRFLAHKGASSLLQVH-GHQGVCPGVAEITSLTRILRGLLDPHLHLYKEEKAL
T-TVEDLSSSDLVAQ---SFKSSKS-----KTQADSDKAKKRQRKHLLAISSFLFAVIWG
FGAH--------------LPS-RL-WPLFDNFMRNSISCLSNYPKPPSSVLVFDLHVNPE
DGTLVPFTGQYLSSRVRGSLGSFHP

PF12775 // ENSGT00910000144015_1_Domain_5 (2546, 2782)

STQTERLLYVVDLLLSNGQPVLLAGEAATGKSAFV
EVLVEPNHSFIHSPIHPALNSAHLRHLLSRGVQGQAQA-NPTSGYHQDLKCSLLFLMEDL
HLAASDSEKTCQPVLETLRQAMDGTIYAHTTLELQTLQPTVSFLATATVPGFWERPLCPR
LFRLFTVLALGSMTQDTFLSRHVRTIQAWLERFPSVEREHTLARALVRASVEAWEAVCNC
FMPSPLRPHYRFSLHSVSHLL

ENSGT00910000144015_1_Linker_5_6 (2782, 3070)

GSLQLLPTRMGLRGFSDSSHHQEYLRWASGLRGTRLTIM
TSMRSMVRLWLHEAQRTFCDRLDSPRERSHCAKLLLEVAQNVFCCAPGTQSLVKDHEE-E
------KEEERVPEVESEGEIAQWEDL-----SNSDSDSEQEEDPYGLQATTGSYISIPT
LSP-SI--R--SLSKESIESVSY--MTEQEEDIKSASSKVQSET-PKSGEQKAPQ-MDLV
SPL--LIPVLLMYPQEEPSDLVFSQELTIGASFETPN-LYLERQWENLEKQLAASAVQLK
LNPNLARCH

PF12780 // ENSGT00910000144015_1_Domain_6 (3070, 3331)

TMAQHVVRLVRVLARPQQHGLLLSVARGTGRRTAITLASSICQVHLFHLPS
-KSKEDISQCLRNTSWRAGVLNQPVALLVPESVDVMTLHRLVALATSGSFPDQYTEADLD
NIEEHL-PKENLVVKYTTKKGMVLHRFYQQVRNNLHM-FFLLGD--HQAQKELPPTLFLR
LLQLTTASVDRYEPWDQDSLIRVAQCHLESA-QSLPLDDGSLKCPDIKASIPTVAKIMVL
IHLSSAYYNQHQCPALPLVTPKTFLDFLDI

ENSGT00910000144015_1_Linker_6_7 (3331, 3452)

FLLQQQMMILQMRARALRIHTALKTLRLMV
ERHSTRTSLVSDLEQQLKGSHKN------------LSIYQEQLEQSKLLYRQQLAECRHQ
ENLIESLVRQHDALQAQQEAFLEQMGKAFLG

PF12777 // ENSGT00910000144015_1_Domain_7 (3452, 3687)

PLSQLQVSDFEEIRSYRAPPESVVQVTDA
LCDLFHHETGWANAKQLLCTENFYQELVFFPKEKLTDSELIKLDQALNAPGMRDAALRAV
STPAANLAVWLWAVLRYGMAHRRGLPTGLLLQQVEATLAREQARLGQFQFQAQETWEKTM
VLNKKLEDAQTCYNLLMESLSKAQGGQYHKWPIKSVLLTPLHMWTTQLQKLKEHCMTVFG
DALLCAAAVMYLGPFPPQRRKELLDKWLSVCRGFQ---EDLDADDIAQELKQ--KSVSKP
-PKTPLLPTRVPFRILSLLSCKSEQHQWDRDLKPQAKSARLAGLLLRSHIHYHSRRWPLL
LDPSNQALVWLNPLPLR-NEWLAPVSAENREKGHE----TNQDIENAEEDELEDDDDGGN
REG--NEARDQTKEEN-K--NA---------GKEQEEQEKEKEKNETGSP-----NPASE
PQGPPLLCLTVLSGADPEL--GPQLLKAAASGLPVLLTNVE--LGLACQELQWLLIREKL
CPPQVQPGFCLYLSTTLPIHALEQ----VLGCELLKGLNVLDLGLNMDVLEEQMLHEILC
REHPELETRWQELNIRAVDTHEAMEAAQEHLLMTLLLQ--NQKRQKPSKFLREMVRIQAK
ICQLNAHGEELEEQKLEEVTMWVPYRQVALHGMAMVEALSPLQNLQPFFCMSLENWLAAT
RRALDSMKPHDIHHGEDLTSHLLQLKKHLTRQLLGSTVAALGLTQLPLVGALGALALLQV
TKKTQKLERLALWPGLAASPSTGQNTQVPGVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPRAWQECGVLELLPSFAGLRAS
LAGHSSAWQDYMSLSSTVLGPAPG--PNPEPLSLLQKLILWRVLRPDCLTSALADLTTSL
LGQPLDENLDAPTMAFEHSQATQPILILLPPPGHPTATLHPVTVIRNLAAKHE-----QH
LHVIALGSEAWDPVSDVVSTLCQAMSKGHWLVLDNCHLMS----HWPTELLQPLLGLLDG
ASVVSDLEL---SAQPESRNVATVHRDFRLWLIVSTEASASLPGVLTQHSMPVFWDQSLE
LGPILIDSMEVVQQGLYKQP-LTQTMPLLLLHGLLLHRQLYGMKLQAHRGRWSQVTLTKV
LQTQDQLSASLSNPSTAMQELAASVFYGGSVGDPEDREALISLTQACLNPSSRSWVQPYT
PQYLLATLMPSPELGELDAMAECKARMHLLPTPSEPRTCGLNEGPKASLMRCQSRALLSA
LQRCSLTWVPSAFRVN--TQCKERRLRQRLVQARRRLVALQGLLANPN--ITGSGPSLGP
RAVGPSSQRPLEGFLETEVLELRQLVVTLQHDLDCLLQRLMGKPPCPSSRCAAVAEALWT
GRLPRPWRPHAPAGPQLPWQWLRQLSSRGHLLVRYLTSGRNENTNELQRIFHLSAFRHPR
RLLLALRWEAVLEH-----SVPNTSLPANQDSGSSATT-SHLPHKCQELSNNPLHIRVEN
DPDPKVPEMGL-LLIGLQVQHAEWDTIDGALQDSSSSQPSPLPPVSVSTRARSANDVPVL
ASLGVYSCPVYMTGPLGTTKLHSRNILMHLPLPTKLSPATCIQQRVHVCSPSLT

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------------------------VFPQVLDYEQLKRLNVLDLSFNPEILEEQILHEVMK
AERPELLTHWQDLQTKTLDTHKTVEAAEEKVLLLMLVQ--KSTHQKQAKFLRAMVRAQAE
MIKHRANYEELEELKLQEIASWAPYKRVVWYGMTVIKAISLLQNLVPPFRMHPEDWLAAT
RQVLNNLKHDDISRGEDLPSHLLQLKAQLTRHFLSSTVATLGLTQVPLVGALSTLALLYT
TTKAPELERLALCPGLAASPSIQPGK

PF03028 // ENSGT00910000144015_1_Domain_9 (4227, 5024)

SVPGMVRPAWLGLRAWHECGILEMLPPFVGLRAS
LASHPDVWQAYLSLSSTVLGPAPGPGPGPDPLNLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENLGAPTISLERSKATQPMLILFPTPGQPMATLHPLTAIQELAANHEQ--GQKH
LEVIALGSLAWDPVSSIISTLCQAINKGHWLVLENCHLMP----HWPKQLLHPLLKLLDG
AKVVSDEELEQLSTQSENMDMTLVHRDFRLWLIVSSEVIASLPXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXQVQLWDSLSNPSAAMEELAASIFYGGPVGDNKDRETLHSLTQACLNPSSQSGAEPHT
PQYLLATLMPSTDLKDLDAVAECKAQIQLLPTPPEPQVCGLSAGTQAWLLCRQSRALLSA
LQRGSAVWVPAARRGS---QREERRLQQRLMQARRRLESLQTLLSEVTRPEESSTE----
GMVEPNGPRLLEDFSEAEVLDLSRLVSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPLWD
GRPAPLCPLHLPACAQPPWPWLRQLSSRGHLLVRYLGTG----NEEPKRIFHLSAFGNPR
RLLLSLRREAAFAKGFQDQCAPGFNLPGCQI---------QFSHRSQELNSNRLHLQVVN
DSNPTVPERGL-LLIGLQLRNAEWDPMTGALQDGPASQPSPLPPVSVTVMARGASDLPNP
AGLTMYSCPVYLEGPLGTTRLHSWNILTYLPLPTKLSLDACIQRRVYACSPPLL

------------------------------------------------------------
-MKRRRRQRSW-LCSLPLPPIPRRPGEVPKQRSWNWHLEPELWARSLRQQLNVQLLSPLG
EKRAGL------SLD---------AVLDSTGQSGTYQTKQRKFLMAATDLEQPTVLKLLL
AELQTLFSAVLQDHSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTQL
QLDLLSAIDHAFPPDSSLLCSASHVDCHPQKKRFHRSPPCPACPFVLAQWGGQQVRQELA
TWLRPLTLPELQHCLGIVGAEVALEETQWLDGLSLLPLALATDIPVQYKSSDTDNVEEEP
IRR----------LASQRPFQKRSSSSSPEVFFSGSQPLNVLNTDKYLKKIYFFYLNVAP
SRYFRPYDLVVVPPKRVNPEHYVFSPFGILHVHPVEGSEVMTLGAWHHQTVLWQQLQLIP
FFKYCLVRKAFTCWRKTMKWQGLCRLRTFLGNHLLLAVPHFGAGLLHINRLLQELHSVSW
LPQEPDQCYELLDLKKALFKENRKALQLLHRCVNLCASIIHLVHEDTYHMQQGLQERVQN
CNRIRAGQGSLYLLKVQRQQLEEKLKQAEAWLLQLGKFARLVNYMICQNLVTILEDEISS
FVANVLQAQRQKPFLSSRLVCGDCCQLASVPNIEHMTEVLSEGLHSIKTSALKLMQSVDK
KTLRDSLYLE----DEEDSSDPEFLMPKIQGQPSDAVRIFCGPNVGLVWPWKSHPITGVL
EVHGYRLRGQYLPPNYSQLQENLDNSLRIQQALTVQQALLEGMMQEVQEFCREHHWITDF
CEYLQAWGPPKLEDLRGCPIRKYVMVVSQLGAWQARLSSMPGELLTEGKLLLLSCRETQA
ELESKLDSVKKDILTQVQNECLSRSQQLMTELTDFIQVFQTISTDIHSIAQCSQKLKEAN
EQYLQLEEQVEYIRSLQEFIRSYFNVFTAESEALEIL-----------------------
-------LVDTWETFQLEKTQASEFLLSKQYAIVPKLQQMMATALAELEGLLKKALSGPF
MDPTQEQRSTESKLVSIEHQFKNTASHLCELHHTYVTFTGDESPVPLPVCGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

LQQH
IWHLYRVISETFSEWKCIAFVKFSLPVAQEKTDGWLAEAAQMNAALGVHSPVLQCCIRML
KEFRSYLPLLVKLGSFQRHNLSYQSLLRAIGLSNLQNMELLTLGQLLTCPLLEFADR--I
NQVWQCEYERVRAQENLQRLQQDWESRRLRLLNFILHVPYESSASEHCKKQ---TVSGPQ
WQVVSKDSGTFILSDYNSLQDSIQKSLQVLFKVLAIQKSGDLHKTALEWVTIMQALG---
ALLEVWMAFQQKWIFLNKVLHEMKIQFPSAELHTRFKALDDQYRMLMRISVADPMVLSLI
-MPSAKRSPYFQGQQLQQMLQAGSVELEGIVMALEAVLYGVCAHFPRLFFLSDSELVALL
AASPEPCEAELWAQRCFPYVHTVRFKSNTTN-EKNMDGRE---------CTQVEALAVLG
EGGEEVRLQGPLLLHSDLPKWLASLENCLRLALVCMLQD

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVAARLTVKPSIGETFKK---
LPQQSQLH----LPLNVQHWLDVYVAE----------------KCVRLSELGTLATTSRH
IHKLAVLVQFI-----SQGGQPLLSVRQASLLSALLVMAVTHRDIAQLLEKHQVSDLTDF
HWARQLKYHLGPPHLHPQSPLQNLKTVVS-TERSLPPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNFEYLGPRL
GPLPSLLLERPVLILLLALEEVACGTLVGPDGVGKKSMVNSLARALGRQLVMMPCLPQIQ
ARCLSNYLQGALQGGAWLLLVGVHLLPPGLLSALGQCLAELHCLYAPLHLKASQSISTMD
-------PTKPQILGSGLFEKHHVSVRLGYGCLLTLRALSAAVPANLHLLLRPVALAL-P
DLQQVAELTLLGAGVQDAASMATRLSKFFSLERELVSGSLPCRLPLLKQILEETIQTLHV
TKKELESQESGSLAAMEEAALLRALVHSPLFSSLDGFRLHNLRELLCGIFPHASLVLAEP
ISRRLMKSLIIEELQQVDLHPSPDLMGSLEQLSEALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMDKI----SAQRSQPVEITHMYPSVLSSQEFLGWLEGSYWHCGIFPRLLRTA
PHCKRVSPREQTEESTGIQYWVVCDGAPSAVWLDSITCLLSDPPQVSLPNGQQIARPPGT
FFLMEVADATCISPTLVGHCALVWCGGEQTWQSMFNVLMASIPREYRLLPHTVIELDQLA
DSLVPATFRFLIRKGASSLLQVH-GHQAVCPGVAEITNLSRILHGLLDAHLGLDEKEM--
--------APDPDDF---TFISSKSTSP-NWPK---------DREHLLVISSFLFAVIWG
FGAH--------------LPS-RF-WPLFDTFIKNSISSLSNYPGLPPATLVFELHVNPE
DGTLVPFTGQYLSSYIKGSLGIFHP

PF12775 // ENSGT00910000144015_1_Domain_5 (2546, 2782)

STQTERLLYVVDLLLSRGQPVLLAGEEATGKSAFV
EALVEPNHPYIDSRVHPALHSTHFRLLLSRGVQDQTQA-SSWSTRHQDSEGSLLFLLEDL
HLATSDAEKSCQPVLEALRQAMDGTVYAHSTLELQTLQPIVNFLATATVPGGSERPLCPR
LCRLFTVLALGSVTQATLMSRHTPSIQAWLERFPSVEQVGILGKALVQASVDAWEAVCHC
FLPSPLHPHYRFSLHSVSQLLGSLQLLPTRGSSQVFEDYFYDKEHLYRVSGLQGSCLTIM
MSLRYVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLEVAQRVFCHGPGPQLLVRDYEG-E
E-----EEEENVPEVESEGELAQWEDL-----SNSNSETEEEEDPYGLQATTSSFSSDPS
VAPSI---K--RVSRETTESISH--KTEQREGTRASSCKLQSKE-FNT-LQKATQ-VDMV
APL--LLPVLLLRPKEKPSDLVFCQELTLGSSSEGPN-LYLERQWGRLEKQLATLAAQLR
LSPHLVQSRPMAQHVARLVRVLARPQQHGLLLSGAPATGRRVAVTLAASVCQARLFHLPT
-GPEEAILQCLRDASWDAGILSHPVALLVPKTVNLTTLYRLVALATVGSFPDQYTEADLD
NIEAHF-PRDNLVNKCNIKKEMVLQRFYRQVCSHLHM-FFLVGD--DQAQNKLPCTIFLR
LLQLATASIDRYEPWDQASLVRVAQYHLEGA-QSLPLDDGPFKCPDLQASIPSVAKAMAL
IHLSAAYYHEHLCPVLPLVTPKTFLDFLDTFLLLQQKMILQIKNRAKRIQNALENLKSLL
EQHSVQTNLVINLEQQLKDSHMK------------LTLTQQQLEQGKLLHKQLLAECRHQ
ENLTENLTKHRDALQAQYEAFLKQMGKAFLG

PF12777 // ENSGT00910000144015_1_Domain_7 (3452, 3687)

PLSQLKVTDFEEIRSYRAPPESVVRVTDT
LCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKMTDTELIKLNDALKSLGMNNRALRAV
SVPAANLAAWLWAVLRYGLAQRRGLPTGLLLRQVDEILTREQARLGHYQLQAQEKLEDIL
TLTKKVQEAYVTYNHMLGALAIAQRGHYKKWPVKPALITPMHTWTTELQNLSGHSMTVFG
DALVCSAAIVYLGPFPPPRRLELLDKWLALCRGFQ---EPLGPDDVAQALKQKQKP-IIM
PPKNPLLPTRFPFSVLSLLSCSSEQHQWDRDLKPQVKSARLAGLLLRSCTHYHSCRWPLL
LDPSNQALNWLSPLPLEENRLLMSPAIWVHHTTHD---------LANSTEPTGGKDASIE
RNEAEEQTPEQKAEEQENQEE-----------EEQEGEEEEEKEMKENELESQESKVALE
AQSSPLLCLTVLSGTDPKL--GAQLCEAAANGQPVLLTNVE--LGLGCQELQWLLHREQL
MPPHVQPGFCLYLSTTLPLHALQK----VLGCELLKGLNVLDLGLNLEILEDQMLHEVMH
RECPELEIRWENLKTSTLDACGAIEAAEEKLLTMLLSKDENSKDEKPAKFLRHIVRIQAK
ICQMQTYCEELKEQKLQEVVLWVPYQQVVWQGIAIVKALSTLQNSLPFFHMTAENWLAVT
RQALDSMKPRDVQHREDLASHLLQLKAHLTRQLLGSTLTALGLTQVPLVGALGALALLQV
TEKAPKLERLALYPGLPASPSTGYQKSDPSVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLTPRIWHECGTLELLPPFAGLRAS
LADHSSVWQDYLSLNSTVLGPAPG--PTSEPLSFLQKLILWRVLQPKSLASALADLTTSL
LGRPLDENLSILTLPFERSQATQPILILLPPPGHPTANLHPLTVIEKLAATHKQ---QKY
LRVIALGSEAWNPVSDVVSTLHQAMLEGHWLVLDNCHLMS----HWPRELLQPLLGLLDG
AKVVSDNEVPLLLAEVESRNVVTVHRDFRLWLIASAEASASLPAVLSQHSMPVFWDQSLE
LGHTLIHSLELAQQEVHMQS-PTQALPLLLLHGLLLHRQLYGMRLQAHRGRWTHMTLTHA
LETQAQLSASLSNPGTAMQELAASVFYGGSLGDIKDREALTSLTQACLRPSSQSRVQPHT
PRYLLATLMPSPELGKLDAIAECEAQMHLLHTPSEPRICGLSEGPQAWLLRRRSRALLSV
LQRSSSSWVPAARTGS---RRTERRLQQRIVQVQQNLESLQAALNNHTRRDQA---F---
ALRGRGTRRPLEDFLKTEALELSQLVGTLQRDLDCQLRQLQGEPPCPSHRCKAVAHALWS
GRLPVPWRPHAPSGPQPPWQWLRQLSCRGQLLVSYLGA--NTGTEVSERIFHLSAFRHPR
RLLLALRWEAALEQ-----RVSSSKFPGSQGPSSR-----HLPNKRRELSSGPLHLQVEN
GPSPKVPEMGL-LLIGLQLLHAKWDPVAGAVQDSSSSQPSPLPPVSVSAGTHRASAGPRA
AGLVVYSCPVYLAGPLGTAKLHSRNILMHIPLPTKLSLATCIQRRVHVCSPPLP

------------------------------------------------------------
---MKPHPQAS-PPSLPMPSASRTPGETQQPKAWNWHLDPQLWARSVRQQLNTCLRFILE
ER-------NPSVEVLDSR-LTECSC-SIQGHSWDCWKKQ-KHLKEVVESEQQTSLKLLL
SELQSLLSAVLQDCSCEAWRYLHAVLGLLPPYREMLTGQLELLPLLEQLYCWAPKVQSQL
HLDLLDAIDKAFPPDTSLLHSSSHVDCRPWMKRSHRGPPCPACPFVKARWGKQQK-QELA
TWLRPLTLPELQHSLGIVGVEVALEETPWLNSLSLLPLALATDIPVQYGSSDAHLAEGEP
AAR---KSQRASESPEEKAFKKKS----SKTSLLKSKVKSLLKTDWYQRKIHFLYLNVAP
DRYFKPYNLVVVPPNQVNPEHYIFSPFGILHVHPVEGSETMTLGAWHRNSTIWHELQRIP
FFKNCLLQKALTCWKKNVRLHGLHRIQTFLKSHLLLAVPHFGAGLLHISRLLQELRSVSW
LPKEPDKSFELMDLQKTIAKENHRALRVFCRFLNLCTSILQLVHEDTYQMQQGLQERVQN
WNRIRKGQGSIYLQRVLCRHLEKKLKQAETWLLKLGKFARMIDYMICQNLVSILEEEITS
FIANTMQVPRENPFLLSQLVFDDNGRLSPMPSVETIIQSLTKGLQAVKTSALKVVQSTDM
RTSMDPLNSE---DGKDQDSNAEFLMPKFHGKSSDAVHLFCGPNVGFVWPWKSHAITDVL
EVRGHRLRGQYLHTNYNHVQEDLDNNIRIQQALAVQQTLLEDMLQEVREFCSEQQWVEGI
YKFLKAWDPQKLEDLRGSPIKDYVVLVSQLKDWQERVSNMPVQLLTKGKLLLLSGHDVQA
ELESKLSSMRKNILAQVQSECWSRNGQLMTEMTDFLQAFQTINSDIHAIAQCSQKLNEAN
EQYGQLEERVEYVRSLHDLIRNHCGLFMAENETLDIS-----------------------
-------LLDIWETFQFERSQASEFLLSKRHSIVPKLQQLMAAALTELEDLLAKALSGSF
MDPSQEQRSTEQQLAALEHQFLNTLNNFNDLRYAYNTFTAKIRDGTP--------GLQ

PF08393 // ENSGT00910000144015_1_Domain_1 (1139, 1600)

QR
IWRLYRIISENFSEWKCMAFTKFSLSMAREKTDAWLTEAARLSTTLGLHSPVLQRCMRML
EDFRNFLPLLTKLGSLQLQNFNCQSLLRVLGLGGLQSFDLITLGQLLNCPLLEFADR--I
NQVWQYDKERIHAQESLQQMQQYWEGRQLRLLNFILHVPYKPPVSERSKRQ---AFRNSQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGELNKIALEWVSIMYSLG---
ALLEVWVAFQQKWIFLNKVLHEMKIQFPGAELNARFKVMDDQYRTLMRISVADPMVLSLI
-VPNAKRSPYFQGQHLQQLLKAGSVELEAIIMALEDVLYGVCSHFPRLFFLSDSELVALL
AAPLETCEAQPWAQRCFPHIKAVDFRSNPIN-EKSKNDQEP----SSSTQTPVETIAVLG
ACGEKVKLQGPLPLHPDLPKWLASLEKCLRFVIVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLVKALKA---
LPQERKVP----MQLYVQHWLDAVEAFPWQCILVAEEIVWRAEMEELLSEWGTMRMIPIH
VHKLEVLVQFIRSQRSSQGEHPLPSVRQTSLFSTLLVMAVNHRDVAQLLGKHRVSDLTDF
HWVRQLKYHLGSSHSNPKGPVQYLKTVAS-AEPSLSPAVCWIDVLGRSFI

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPKL
GPLPSLMHERQVLVLLLAMEEVACGTLLGRDGLGKSETVNSLSWALGRQLVMMPCLPQIE
FRCLSNYLNGALQGGAWLLLENVHQLPPSLLSALGQRLDELHHLYAPLYQKASQNISTIN
-------PTKPLFIGAGFFEKHHVFMRLGYGCFLTFHALSPDVPANLHLLLRPVALAL-P
DLHRVAEVYLLGAGVKDASRMATQLSKLFSLERELVSGTLPCRLSLLKQVLEDTVQTLNA
PVEENNSEQPDNLAAPEEAALLQALLHSPLFSILDGLRLQKLRELLCGIFPNASHMLAEP
VTHRLMRSVVVEELQQVGLLPTPNVLMSLEQLSQALSRASGILLLGPAGSGKSSCWKSLF
KIQNRLAAMEQT----STQGFQSVEIAHLYPSVLSSQEFLGWSEGPSWHYGIFPKLLHAA
PHCKNVNSEEQSEEVTRIQQWIVCDGTPNPTWIDSITCLLSDPPQLSLPNGQQIARPLST
FFLMEVAEAAGMSPTVVGRCALVWCCGEQTWQCMLNVLMASLPHEYHLQQETVIELNSLA
EVLVPAMLRFLTRIGASSLLQVH-GHQTVCPGVAEVASLARILRALLDPHLRLYEEEKPR
--VQENFSGSDLATQ---SFKSSKS-----RVQSDSDGMTKKQRRHLLAISSFLFATIWG
FGAH--------------LPS-RH-WPLFDNFMRDFISSLSNYPEPPPSALVFDLHVNLE
DGTLVPFAGQYLSSCVKGNLGTFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2784)

SQTERLLYVVNLLLSDGQPVLLAGEIATGKSAFV
EVLVEPSHPSIHSPIHSALSSAHLRHVLSRGVHGQTQATGSFLGYYQDSKGSLLFLMEDL
HLASSDPEKSCQPVLETLRQAMEGTIYTRNTLELQTLQPTVNFLATATVPGYSERPLCPR
LFRLFTVLALDNMSQDSLLRRHVPSIQAWLERFPSVEREHTLARALVRASVEAWEAVCNC
FMPSPLRPHYRFSLHSVSHILESLQLLPTRIGSRGFADSFHHQEHLRRVSGLRGTRLTIM
MSMRVVVRLWLHEAQRTFCDRLNSDRERSHCAKLLLEIAQSVFCCGPESQPLVKDFEE-E
------VEEEKVPEVESEGEIAQWEDL-----SSSDSESEEEEDPYGLQVTTGSFLGDSS
LAPLPL--R--LVNK-NTGSVSQ--MAEQEEEITASFGKLQSET-PKSEWQTATQ-MDFS
LPL--LLPVLLFYPQEKPSDLVFSLELTLGSNPESPN-LYLERQWETLEKQLAASAVRLK
LNPHLTQGHMMTQHVARLVRVLARHRQHGLLLSVTRGTGRHTAISLASSICQAHLFHLPS
-ESEEAIFQCLRDASWCAGVLNQPVALLVPETVNVAIFHRLVALATSGSFPDQYTEADLD
NIEEHL-PKENPVVKPIIKKDTVLHRFYQQVCSNLHM-FFLMGD--DQAQKQLPSTLFLK
LLQLTIANVDRYEPWDQASLVRIAQYHLEDA-QSLPLDDGSLKCPDIKAFIPNVAKIMAL
IHLSSACYHQHVCPALPLVTPKTFLDFLDMFLLLQQQMVLKMRMKA-RIHSALKTLRLLV
ERHSTQTNLLSDLEMRLKGSYKN------------VGMYQSQLEESKLLYKQKMAEC

PF12777 // ENSGT00910000144015_1_Domain_7 (3418, 3687)

QHQ
ESLIENLVKQQNALQAQQEAFLEQMGKAFLGPLSQLQVADFEEIRSYRAPPDSVVQVTDA
LCELFHHETGWANAKQLLCTEDFYQELIFFPKEKLTDSELIKLNQALKAPGMRDAALRSV
SIPAANLAIWLWAVLRYGLAQRRGLPTGLLLRQVEATLAREQVRLGKFQFQAHDLLEQIL
SLTKKLEDALASHNLVMETFNQAQCGQYHKWPMKSALLTPMHMWTKQLQKMKNNCKTVFG
DALLCSAAIVYLGPFPPQRRQELLEKWLSLCQGFE---EALEPDDVAQTLKQ--KSVGVP
-PKNPLVPTCTPFRILTLLSCGSEQQEWDRDLKPQARSARLLGLLLRSHIYYRSYRWPLL
LDPSNQALAWLNPLPQKQNMLLAPP-KESRAKYHM----TNQDREDETED-------EED
RNKANGQTKEQKTEENKS--EE---------GKEKEEQEAEKEKNEI---ESLNSSTPSE
TQ-SPPPCLTVLSGADPEL--GPQLLEAASNGLPVLLTNME--LSLSCQELRWLLSREDL
SPPHVQPGFCLYLSTTLPIHALER----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RERPELETRWQDLKIRAVDTYEAVMAAEERLLAILLLQ--NQRRQKPSKFLREMVRTQAK
ICQLNAQMEEIEEQKLQEMVLWAPYRQVACHGIAVVEALSSLQKLLPFFCMNLENWLTVT
RRALDSMKPHDSHHGEDLPSHLLQLKIHLTRQLLSSTVAALGLTQAPLVGALGAIALLQV
TKKTPKLERLALWPGLSASPSTGHNTQGPGMARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGLRAWQECGALELLSPFAGLRAS
LAGHSSVWQDYLSLSSTVLGPAPG--PNSEPLSLFQKLILWRVLRPDCLAAALTDLTTSL
LGRPLDEDLGAPTMIFEHSQATQPILILLPPSGHSIATLHPVTVIRKLAANHE-----KH
LHVIALGSEDWDPVSTIVNTLCQAMLQGHWLVLDNCHLMP----RWPRELLQPLLGLLDG
AKVVSDSEL---LAEPENRGVATVHRDFRLWLIVSTEASASLPGVLIQHSMTVFWDQSLE
LRRILIDSVD-LQQGLCMQP-FSQTLPLFLLHGLLLHRQLYGIKLQAHRGRWSQVTLTKI
LQIQEHLWASLSNPGAALLELAASVFYGGSLRDPGDREALISLTRTCLDPKSMSWVQPHT
PQYLLATLMPGPELGELDARTECKARMHLLPTPAEPRVCGLNEGPKSWLLRRQSRALLSV
LQQCSPTWVPSACGGI--NQRKERRLRQRLVQAKKRLVALQALLSN-R--NRSGQCITPW
AVLGPNAHRPLEGFLETEVLELKQLVCIVQRDLDCLLQQLKGETPCTSSRCAAVAHALWA
GRLPRPWRSHAPAGPQLPWQWLRQMSRRGHLLIRYLDSGTSENANEPERIFHLSAFRHPR
RLFLALRWEAVLES-----RVPSPNLPGIQGSGSS-----SLPPKRQELNNHPLHIWVEN
GPNPKVPEMGL-LLIGLQLHHAEWDQMDGALQDSFSSQPSLLPPVSVSTQARGANNTPIS
AGLGVYYCPVYMTGPLGTTKLHSKNILMHLPLPTKLSLDTCIQRRVHVCSPALT

------------------------------------------------------------
--------------------------------------------------------LVQE
ERRVGLSPDEASSDALESW-HSVCAL-DSKQQPSDCQRKRRQFLKPVTESKQPTVLELLL
TELRTLFSAVLQDRSPAAWHYLHGVLGLLHPYREFLVGHLDLLPFLEQLYCWAPWVQTQL
QLDLLDAIDQAFPPDNSLLDSASHADCYPQKQRFHHGRPCPVCPFVQARWGGQQVKEKLT
TWLRPLTLPELQHCLGIVGAEVALEETLWLDGLSLLPLALATDIPVQYKSCDTNNTEEET
VRGRETRSQLVYDAPREKTFQKRSIGFLPETSFLGSQVMTILKTERDLKKIHFLYLNVAP
SRYFSPYSLIVVPHNKVNPEHYVFSPFGILHIHPVDGSETMTLGTWHRHSVLWQQLQFIP
FFKYCLLRKSLVCWKRNVRLQGLHRLRSFLGNHLLFAVPHFGAGLLHISRLLQELRSVSW
LPRELDHCYELLDLQKALAKEKHKGLRLLHRCVNLCRSVLQLIHEDTYHMQKNLQERVQN
CNRIRAGQGSIYLQKVQHHQLEQKLKQAEAWWLQLGKFARLVDYMICQSLVSILEEEITS
FVANILQTPRQEPFLSSHVVFDDCGQLSHMPCIENMIQILTGGLQSVKASALQVIQSAEM
KTSWDSLHSE--EKDEEEDLNTEFPMPKFQGQPSEAVRIFCGPNVGLVWPWKSHPIAGIL
EVRGHRLWGQYLPPNYRQLQEDLDNNPRIQQAMMILQVLLEGVLLEVQEFCKEHHWTIGI
HEFLQSWGPQKLEDMRGCPIKNYMLLVSRLNVWQTQVSNMPTKLLTKGKLLLLSCHDVQA
EMESKLNNIRKDILAQVQNECWSRSQQLMTELTDFMNVFQIISSDIHTIAQCSQKLNEAN
EQYVKLEERIEYIRSLHELIRNHFGIFSAENEALDISVRRRFGESPIPPGPPS-PPYLLH
CPLLVPQLLDVWEAFQFEKSQASEFLLSKQHAIVPKLQQLMATALAELEGLLEKALSGPF
MDPAQEQRSIECQLISLEHQFQDTVSHLSELQHAYTIFTGDESPVSSPIGGSRPIVQ

PF08393 // ENSGT00910000144015_1_Domain_1 (1138, 1600)

QQH
TWHLYRVISENISEWKCMAFAKFSLAMAQEKIDVWLTEAARISATLRLHSPVLQHCMRML
EEFRTYLPLLTKLGSLQLQNPTCQSLLRALGLGSLHNIELLTLGQLLTCPLLEFADR--I
NQVWQYENERVHAQETLRQLQRYWELRKLRLLNFILHVPLKTSASERSKRQ---MLHSPQ
WDVVGKDSGTFILSDYSSLQDSIQESLQMLFKILALQKSGDLNKIALEWVTIMHSLD---
ALLEVWVTFQQKWIFLNKVLHEMKIQFPSTDLNSRFKAMDDQYRTLMRISVADPMVLSLI
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMALESVLYGVCAHFPRLFFLSDNELVALL
AATPESCEAQLWVQRCFPHVHAVSFKSHPTD-EKNLDDQVS----SPSTQTQMEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVRMLQD

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLVWGPSLGEACKQ---
LPQ----------QLYVQHWLDLIQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSTH
MRKLEVLVYFMRAQRGSQGGQPLPSARQTSLLSALLVMAVTHRDIAQLLEQHRVSDLTDF
HWARQLKYHLGSPHTIPQSPLQSLKTVAS-TEPSLPPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPDGMGKRTLVNNLAQALGRHLVMMPCSPQTE
ARCLSNYLNGALQGGAWLLLEAVQHLPLGLLSALGHRLAELHHLYAPLYQEVSRSTSTID
-------PTQPQLLGSGYFEKHQVSVRLGYGCLLTLRALSPAVPANLHLLLRPMALAL-P
DLQQVTELTLLGAGMRDASRLAARLSKFFSLERELVSGPLPCRLPLLKQILEDTVQALNV
AKEEFKSQQPQSLATVEEAALLRALLRSPLFSIHSGLRLHNLRELLFGIFPSASQVLAEP
MACRLVKPLMVEELQQLGLHPGSDVLRSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMTD------NQGYQHVEITHLYPSVLSPQEFLGWLEGPCWHHGVFPRVLRTA
GQCNIMGPKRQTVDSMGIQHWIICDGASSAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADATGMSPTVVGQCALVWCGGEQTWQCILNVLMASLPSEYRLQHQTVSELNHLA
EVLVPATFRFLTGQGASSLLQVH-GQQAACPGVAEVTSMARILHGLLDSHLRLEEEKAH-
--GPEDLSCSDPMAQ---SFKSSKSSSL-NRFQTDCNDLSKMHREHLLAVSSFLFALIWG
FGAH--------------LPS-RL-WPLFDNFMRSSISCLSNYPEPPPSALVFDLHVSSE
DGTLVPFTDKYTSSHVKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2783)

QTDRLLYVVDLLLSGGQPVLLAGEAATGKSAFV
KALVEPTHAYICSSIHPAFRSTHLRLLLSRGVQGQTQT-SPWPRHHQDSKGSLLFLLEDL
HLAASDSENSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMSQATLLSRHVPSIQAWLERFPSMEREGSLARALVRASVEAWETVCNC
FMPSPLHPHYHFSLHSVSHLLSSLQLLPARTGSRGFVDCPDHQEHLRRVSGLRGTRLTMM
MATRNMVRLWLHEAQRTFCDRLDSPRERSYCANLLLEVAQSVFCCGPGHLDKDR------
D---EEDEEERVPEVESEGELAQWEDL-----SNSDSETEEEEDPYGLQVIRGSHPSNPS
QAPSI---R--PVSRETMESISH--KLRQEEGTRASSYKLQEERLSKTRWQKAPQ-MDLV
SPL--LLPVLLLRPQEKPSDLVFSQELILESNSESPS-LYLERQWENLEEQLATSAARLR
LNPHLAQCNSMAQHVAHLVRVLARPQQHGLLLSGALGTGRHTAITLASSIYQARLFHLPS
-GSEEAILQCLRDASWHAGMLSQPVALLVPKNVDLITFHRLLALASSGSFPDQYTEADLD
SIEEHF-PKENLCVKLNIRKEMVLQRFYQQVCSHLHM-FFLIGD--EQAHKQLPSTLFLR
LLQLATASIDHYEPWDQAALVKVAQHHLEGAGQRLPLEDRSWKCPDLQTSIPSVAKAMAL
IHLSAAYYHEHLCPVLPLVTPKTFLDFLDTFLLLQQQMTLQMKNKAQRVQNALENLRMMI
EEHKIHANLVFDLEQQLKGSRKS------------LSIFQQQLEQSEFLYKQQLTRC

PF12777 // ENSGT00910000144015_1_Domain_7 (3418, 3687)

QQQ
ENLIENLTKQQDALQAQQEAFLEQMGKAFLGTLSQLQATDFEEIRSYRAPPESVVQVTDV
LCDLFHHETGWANAKQLLSTEDFYQELVFFPKEKMTNSELLKLHQALKAPGMSDAALRAV
SIPAANLAVWLWAVLHYGLAQRRGLPTGLLLQQVEATLAREQARLGHYQFQAQEILEHNL
VLTKKMEDVQTFHKYMAETLNWAQYGQYHKWPIKAALLTPMHSWTMQLQKLKGHSLTMFG
DALLCSAAIVYLGPFPPSRRQELLDKWLALCRGFQ---EALGPDDVAQALKKKQKYVSMP
-PKNTLLPTSSPFSILSLLSSESEQYQWDRDLKPQAKSARLAGLLLQSPTHYCSCRWPLL
LDPSNQALIWLNPLPLEENRNVAPAPTGDRGKDLM----RKQDRDTKEKDTKEEDVDSED
SNEVKDQKKEQKTEERKNEEKEREE-----K------EEREKEGKEEKETESQGSKPASE
TWSPPLPFLTVLSGADPEL--GPQLREAAAGGLPVLLTNME--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLHGLEK----VLGCELLKGLNVLDLGLNVEMLEEQMLHEILS
RECPELETRWQDLKIRILDTCEAIEAAEERLLLM-LLQ--NPKHRKPAKFLRNMVRVQAE
LCQLRAHCEELEGQKLKEVALWAPYRHVVWHGMAMVKALSPLQNLLPLFHMRQDNWLAAT
KQALDSMKPHDLQHGEDLASYLLQLRTKLTRQLLGSTVAALGLTQVPLVGALGALALLQV
TRKASELERLALWPGLAASPSTSLSKPAPGMARPV

PF03028 // ENSGT00910000144015_1_Domain_9 (4236, 5029)

WLRPRAWRECGMLELLSPFVGLRAS
LASHSSIWQAYLSLSSTVLGPAPG--PGSQPLSLLQKLILWRVLRPECLADALADLTTSL
LGRPLDENLGAPTIPFEHSRATQPMLILLPPPDHPTATLHPLTVIQKLAAKHQ---EQKH
LQVIALGSEDWDPVSDVVSTLCQAMYKGHWIVLDNCHLMP----HWPKKLLQPLLGLLVG
AKVVSDLELELLSAQPGSRNVATVHRDFRLWLIVSAESSTSLPAVLIQHSMPIFWDQSLE
LGHILIDSVELAQQGFYKQP-STQSLPLLLLHGLLLHRQLYGMRLQAHRGHWSQVTLTQV
LQTQDQLWATLSNPRDAMQELAASVFYGGPLGDTKDREALISLTQTCLSPSSGNWVQPHT
PRYLLATLMPSPELGEQNAMADCKAQMHLLPTPSEPRICGLSEGPQAWLLRRRSRALLSA
LQRCSPTWVPPSRGGA---WRAERRLRQRLVLANQRLESLRDLLTDTARQDEC---AAPW
AVLGPNARRPLEGFLETEALELSQLAGMLQRDLHCLLQQLKGEPPCASRRCAAVAHALWT
GRLPQPWRSHTPACPQPPWHWLQQLSRRGQLLVRYLGMGVHAGTDVPERVFHLSAFRHPR
RLLLALRWEAALNQ-----NVSSPNFPGSRGSGSS-----QLPYKRQELNSKPLLLRVEN
GPNPTVPEMGL-LLTGLQLLHAEWDPIAGALQDSSSSLPSPLPPVSVRAQARGTSDLPAP
AGLAVYSCPVYMAGPLGITKLQSGNIMMHLPLPTKLSPATCVQRRVHVCSPPLL

------------------------------------------------------------
---------------------------------------------------------VSE
ERRVGLSPKEALSDALESQ-HSVRVP-DSKGQPRACQRKQRQFLKPVTESEHPTVLELLL
AELRTLFSAVLQDGSPAAWHYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPRVKCQL
QLDLLEAMDRAFPPDNSLLDSASHTDCRPRKQRFHHRPPCPACPFVQARWGAQQVKEELA
TWLRPLTLPELQRCLGIVGAEVALEEAWWLDGLSLLPLALATDIPVQYERSDTDNTEKEP
VGRRDTRSKLDYEVPRKKSCQRRSTRVLLDISSLGSQMMTILKTEGFLKKIHFLYLNVAP
NRYFRPYDLMVVPPNRVNPEHYIFSPFGILHIHPVEGSDVMTLGTWHRHTVLWEQLQCIP
FFKYCLLRKSLTRWKKNVRLQRLHRLQTFLGNHLLSAVPHFGAGLLQISRILQELRSVSW
LPQELDQCYEVLELKKALAKEKYKAQRLLHRCLNLCTFILQLIHEDTYHMQQGLQERVQN
CNRIRTGHGSIYLQRVQRQQLEQKLKQAEAWLLQLGKLAHLVDYMICQSLVSILEKEITS
FVANILQAPRQKPFFSSQLNFNDCGQLSHMPNVENMIQILSEGLQSIKTSALQVIQSADQ
KTSWDSLYSE--E-DEEEDSNTEFPLPKFQGQPSDAVRIFCGPNVGLIWPWKTCPIAGLL
EVRGHRLRGQYLPHNLEQLREDLDNSSRIQQALTKYHMLMEGMLREVQEFCSEHHWLTTI
YDFLQSWGPQKLEDMRGCPVKNYVRLVSLLNHWQDRVSNMPIKFLTKGKLLLVTCHDVQA
EMESKLDNMKKDILAQVQNECWTRSQQLMTELTEFTRVFQNINSDIHAIGQCSQKLDKAN
EQYMELEKRIEYIRALHELIRTHFNLFSAENEALDISVRGQFRESPIPPGPPPPQPHLLH
YPLLVSQLLDVWEAFQFEKSQASEFLLSKRHAIVPKLQQMMAAALAELDSLLEKALSGPF
MDPTQEQRSTERQLISMERQFQDTVNHLGELHHAYVTFTGDERPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTNVWLTEAARMCATLGLHSPVLQRCMRIL
EEFRNYLPLLTKLSSLQLQSPICQSLLRALGLGSHQNLERLTLGQLLACPLLEFADR--I
NQVWQYENNRIQAQETLRKLQRHWEVRQLRLLNFILHVPYKPPVSERSKRH---MLHSPQ
CEVVDKDSGTFILSDYSSLKDSIQESLQVLFKVLAIQKSGDLHKISLEWVTIMHGLS---
ALLEVWVTFQQKWIFLNKVLHEMEIQFPNADLDSRFKATDEQYRALMHISVADPMVLSLI
-VPSAKRSPYYQGQQLQQLLQAGSAELEGIIMALESVLYGMCAYFPRLFFLSDSELVALL
ASPLESCEAQLWVQRCFPHVHAVSFKSRSTD-EKNRNDQAP----SPSTQAELEALAVLG
VGGEVVKLQEPLPLHSDLPKWLASLEKCLRLALVHMLQN

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVAARLAQGPSLSEAFKQ---
----SQLP----QQLYVYRWLDLVEAFPWQCVLVAEEVVWRAEMEEALLKGRTPAMATVH
TRRLEALVNFVRGQRGSQDGQPLSSVRQTSLLSALLVMAMTHRDIAQLLEQHQVRDLTDF
HWVRQLKYHLGSSHMILQTPLKSLKAITS-TEPSVSPAACWVDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERTTLVLLLALEEVVCGTLLGPDGVGKVATVKSLAQALGRQLVMLSCSPQIE
AQCLSNYLNGALQCGAWLLLDAAQHLPSGLLSALGQRLAELHHIYAPLYQEASQTTSTTD
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLTLRALSPVVPANLHLLLRPVALAL-P
DLQQVAELTLLGAGVRDASRMATRLSKFFFLERELVSGPLPCRLPLLKQILTDTIQTLNE
TNGKPKTQQQHSQAAIEEAALLHALLRSPLFNILNGLRLHNLRELLCGLFPNASHVLAEP
MTQRLLKPLTVEELRQVGLHPSPDILGSLEQLSQALCRASGILLLGPAGSGKTTCWHSLF
KIHNRLAAMEAT----STHGYQPVEITHLYPSVLSPQEFLGWIEGPCWHHGVFPRVLQAA
SQCNNMGPKGQKGESVGIQHWIICDGASSTAWLDSITCLLSEPPQLSLPSGQQIARPPGT
FLLMEVADATGMSPTVVGCCALVWCGGEQTWQCVLSVLMASLPHEYHLQQQTLTELNRLA
EVLVPATFRFLTRHGASSVLQVH-GQQAVCPGVAEVTSLARILRALLDLHLSLEEKKAH-
--GREDLSFSHPVSQ---SIKSSKRSSL-NQAQADSNDVSNNHREHLLAVSSFLFG--WG
MGEA--------------EAS-H----------------KLKCCNPPPSALVFDLHVSPE
DGTLAPFTGQYLSNHVKAPLGTFHPI

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2782)

TQTEPLFYVVDLLLSAGQPVLLAGEAATGKSAFV
EALVEPSHPYIYSTIHPAFSSTHLRLLLSKGVQGQAQA-SL-PGHHQDSKGSLLFLLEDL
HLATSDPEKSCQPVLETLRQAINGTVYAHGTLELQTLQPIVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTKATLVSRHVPGIQAWLERFPSMEREGVLARALVWASVEAWEAVCNC
FMPSPLCPHYRFSLHSVSQLLGSLQLLPTRIGSRGFVDCPKHQEHLRRVSGLRGTRLNIM
VATRNMVRLWLHEAQRIFCDQLDSPRERSYCAKLLLEVAQSVFCCGLRPQHLGKDLEEEE
------EEEEKVPEVESEGELAQWEDS-----SNSNSETEEEEDPYGLQIIRSSYPTNPT
QTPSI---K--PAIKETRESISH--EIRQEKDTRASSPQLQENKSSKSWWHKAPQ-MDQI
SPL--LLPVLLLRPQEKPSDLVFSQELILRSNSESPN-LYLERQWESLEEQLATSASQLK
LSPNLARCHSMAQHVARLVRMLAKPRQHGLLLSQAEGTGRHTAITLASCICQARLLHLPS
-GSEEDILQCLRDASWHAGMLGQPVALLVPKRVNLITLHRLLALATSGSFPDQYTEVDLD
AIEEHF-PRENTGAKQNIKKEMVLPRFYQQVCSHLHM-FFLIED--EQSRKQMSSTLFLR
LLQLATASIDHYEPWDQAALVKVAQHHLERA-QSLPLDDGLWKGPDLQASIPSVAKAMAW
IHLSAACYHKQLCPVLPLVTPKTFLDFLDTFLLLQQQMILQMKNKAKQIQNAMMNLKMLI
NEHNAHANLIFSLEQKLIDSRKN------------LSIFQQQLEKIKLQYRWQLTECRHQ
ETLIESLTKQRDILRDQYEAFLEQMDKAFL

PF12777 // ENSGT00910000144015_1_Domain_7 (3451, 3687)

GPLSQLQVADFEEIRSYRAPPESVVRVTDA
LCDLFHCETGWASAKQLLCTEDFYQELVFFPKEKMTDAELVKLHLALHAPGMSNAALQAV
SASVARLATWLWAVMRYGLAQRRGLPTGLLLQQVEVTLAREHARLGHYQFQVQEFLEQSL
ALVKKVEDAQVAYNSVVEALNWALSDQYHKWPIKAALLTPMYSWNIQLQKVKEHCITVFG
DALLRAAAITYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQIFVNMP
-PKKPLLPTRSSFSILSLMSSVSEQCQWDRELKPQAKSARLAGLLLRSTTHYSSCRWPLL
LDPSNEALMWLNPLPLEENTGMVPS---GRGKRLV----RNQNKESKEEDRKEEDDDSED
SQEAKHQTKEKKREERENKEEE------------------------------YETQPASE
TQSPPLPYLSVLSGADPEL--GPQLLGAAAGGLPVLLTNVE--LGLECQELQWLLHREQL
SPPQVQPGFCLYLSTTLPLHALEK----VLGRELLKGLNVLDLGLNMEILEEQMLHEILF
RERPELENRWQDLKIRALDACEAVEAAEEQLLMRLLLQ--NSKCQKPAKFLRNMVRAQAE
LCQLRAHSEEVEEKKLQEMVLWAPYRRVVWHGMAIIKALSQLQNLLPLFRMRPENWLAVI
KQALDRMKPCEIHRGEDLASHLLLLRTHLTRQLLGSVVAALGLTQVPLVGALGALALLRV
TRKASELERLALWPGLAASPSTSHSKKVPRVTRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWVGPRAWHECELLELLPPFVGLCAS
LAGHSRVWQAYLSLSSTVLGPAPG--PGSEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENLGAPTMPFKHSQATQPMLILLPPPGHPTATLHPLSVIQKLAAKHEQ--GQKH
LQVIALGSESWDPVSVVVSTLCQAMNKGHWLVLDNCHLMP----HWPKELLKPLLGLLDG
AKVVSDPELELLLAQPQSRNVTTVHRDFRLWLIVSAESTASLPAVLTQHSMPVFWDQSLE
LGHVLIDSMELAQQGLYMQP-PTQALPLLLLHGLLLHRQLYRMRLQAHRGRWSQVTLTQV
LKIQDQLWASLSNPSAAMKQLAASVFYGGPVGDTEDRKVLTSLTQACLSPSSGSWVQPHT
PQHLLATLMPSPELGELDAMAECKAQMQLLPTPPEPRICGLSEGTRAWLLRRQSRALLSA
LQLSSPAWVPAARGSA---QRTERRLRQRLVQATRRLESLQMLLTNPARQDEF---RAPW
AVLGPNARRPLEGFLEVEALELNQLAGMIQRDLNCLLQQLKGAPPCTSRRCASVAHALWN
GRLPKPWQAHAPARPQPPWHWLRQLSRRGQLLVRYLGVGA-------EHIFHLSAFSHPR
RLLLALRWEAALNQ-----NVSASNRPGSQGLGFT-----QFPYRRQELKSSPLHLQVEN
GPNPSAPESGL-LLIGLQLLHAEWDPIAGALQDSPSSQPSPLPPVSVSTRAPNATDLPPP
AGLPVYSCPVYMAGPLGTTKLQSRNILMHLPLPTKLSPATCVQRRVHVCSPPLL

------------------------------------------------------------
---MKPHQHVP-LSSFPLPSVPHCPGEIHQPGAWNWQLDPEQWAGAIRRQLNAWLLLVSD
-E-------EASSKALES-RHSVGVL-DKAEQRQACQGKKRQSLKAVTWSKRPTVLELLV
AELQTLFSKVLQDGSPAAWNYLHAVLGLLPPYRALLVGRLDLLPFLERLYRWAPWVQAQL
HLDLLDAIDQAFPRDTSLLEGTSHVDCYPQKKRFHHGTPCPACPFVQAQWEGQQVEDDLA
TWLRPLTLPELQHSLGIVGAEVAVEETQWLHGLRLVPLALATDIPVQYESSDPDNAEEEP
VGRTETKSQLDLEVPEEKTLQKRS-------------------TERYLKKIHFLYLNVAP
SRYFTPYSLMVVPANKVNPEHYIFSPFGILHVHPVEGSEAMTLGTWHRHSVLWQQLQLIP
FFKYCLLRKALASWKKSVKLQRLHQHRSFLEKHLLLAVPHFGAGLLHISRLLQELHSVSW
LPHEADQCYELLDLRRALAKENHKALRLLYRCLRLCTSILHLIHEDTYQMQQGLQQRLKN
CKKIRTDQTSVYLQKAQCQQLEQRLKQAEAWLLQMGQLARLVDYMICQNLVSIIEEEITS
FVANILQAPRQKPFLSAQLVFDSSGQLSQEPCIENMIQTLTVGLRSTKASALKVFWFGQG
-SGWRNSLQGIPYEDEEDYSDSDFMMPKFQGQPSDAVDVFCGPNIGLVWPWKSRTVTEAL
EVHGHRLRGQYSPLDYKQLQEDLDNSPQIQQALAVQQALLEDMLQEVQEFCRDYHWMTGI
YEFLQAWGCQKLESMRGYPIKNYVMLVTRLNAWQAQVSRIPMELITRGRLLLLSCRNIQA
EMESKLVNIRKDILEQVQNECQSRSQQLITELTGFMKAFQTINSDIHSIAWCSQKLNEAN
ERYAELEEQMEYTRSLYELIRNHFGLFSAENEALDIS-----------------------
-------LMDTWESFQYEKSQASEFLLSKRHAIVPKLQQLMATALVELEGMIEKALSGPF
MDPAQEQRNTERQLISLERQYQNTVSSLSDLHHAYTAFTGDESPVPLPVCGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

QQQH
IWHLYRVISENISEWKCMAFAKFNLALAQEKTDGWLTEAARVSATLGLHSPVLQRCMRML
EEFRSLLPLLTKLGSLQVQNLNCQALLRALGLSSFYSIELLTVGQLLSCPLLEFTDR--I
NQIWRAENIRNHAHEALLRLRRAWEARQLRLFNFILHVPYESPVSERSKRQ---ASRSPQ
WQVVGKDSGTFILSDYSSLQDSIHESLQVLFKILAIQKSGDLNRIALEWVTIMHGLS---
ALLQVWVTFQQKWIFLNKVLHEMKIQLPSPELSTRFEAMDAQYRTLMQISVADPLVLSLI
-VPSAKRNPLFQGQQLQQLLQEGSMDLEGIIMALESVLYAVRAHFPRLFFLSDSELVALL
AAPLESCEAQLWARRCFPHVHALSFESSETA-KD-TDDLES----SPSIQTQVEVLAVFG
AGGEEMKLRGSLLLHPDLPKWLASLEESLRLALVHNLQD

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVAARLALGPSLDKAFKQENH
LPQESQLS----PKMYVQHWLDLVQAFPWQCVLVAEEVAWRASMEEALLEGRTLAMVPMH
VRKLEVLVHFLRAQRASQGEQPLPSVRQTSLLSALLVMAVTHRDIAQLLQEHQVSGLTDF
HWVRQLKYHLGSPHTAPQSPLKGLKTVVS-TETFLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GSLPSLLPERPALVLLLALEEVACGTLLGPSGVGKGAIVKSLAQALGRQLVVMPCLPQME
ARSLSNYLNGALQGGAWLLLEAAQHLPLGLLSSLGQRLAKLHHLYAPLYQEASRSTSTID
-------PTHPWLLGSSFFERHHVDMRLGYGCLLTLRALSPAIPANLRQLLRPVALTL-P
DLQQVAELTLLGAGIRDASRTATRLSKFFSLECELVSGPLPCRLPLLRKVLEDTIQALNL
TKKDPESEQPRSLATMEEATLLRTLLRSPLFSLLEGPHLQDLQKLLCGLFPTASQVLAEP
ATPRLRKSLLVEELRQGGLHPSPDILGSLDQLSQALGQASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDP----TTQSCQPVEITHLYPGVLSLQEFLGWLEGPCWHNGVFPRLLREA
SRCKNVGPRGQVQEPVGIHHWIICDGASSSSWLDSITCLLGDPPQLSLPNGQQIARPSGT
FLLMEVGDTTGMSPTVVGRCALVWCRGEQTWQGILSVLMAALPREYRLQPQTVAELSHLA
EGLVPATLQFLTCQGVSSLLQVH-GQRAICPGVAEVTSLARILRCLLNPYLRIDEEEKAH
--IPEDLSYSDSKCIVARSIKASKTS--------SLDAVPSKRREHLLAISSFLFAVIWG
FGAH--------------LPS-RL-WPLYDTFLRDSISCLSNYSELPPSDSVFDLHVCPE
DGTLAPFTGQYLGSRIKGIQGTFYP

PF12775 // ENSGT00910000144015_1_Domain_5 (2546, 2782)

SPQTERLLYVVDLLLSEGHPVLLAGEAATGKTTFV
EVLVEPQHPYINSPIHPAVGTTHLRLLLSREVQGQSQA-SPWTGRHPDSKGFLLFLLEDL
HLAASDPEKSCQPLLETLRQAIDGTVYTHSTLELQTLQPGVNFLATATVPGFCERPLCPR
LSRLFTVLALGSMTQATLLSRHMPSMQAWLERFPSVERESVLARALVRASLEAWEAVGKC
FMPSPLRPHYRFSMHSVSQLL

ENSGT00910000144015_1_Linker_5_6 (2782, 3071)

GSLQLLPVRVGSRGFVDCLNHQEHLRRVSGLRGTRLMIM
MATRNIVRLWLHEAQRTFCDRLDSPRERSFCARLLLEVAQNVFCCGPAPQSLGKGYEEEE
-------EEEKVPEVESEGELAQWEDL-----SNSGSETEEEEAPYDLPVTTGSQSNDS-
-APPA---A--PVRKMTMGNMSQ--KTTQEEGTRTSSYKLQPNK-SKNLYQKAAQ-EDMV
SPL--LLPMLLLRPQERPSDLVFSQELILESNSESSN-LYLERQWVSLEEQLATSAAQLR
LSPHLARCHS

PF12780 // ENSGT00910000144015_1_Domain_6 (3071, 3329)

MAQHVARLVRVLARPQQHGLLLAGVQGTGRCTAVTLAAGICQTRLFHLPC
-GSEEAVLRCLREVSWHAGTLGQPVALLVPKGVDLTTFHRLLALATSGSFPDLYTEADLE
NIEGHL-PRDSVSVKQNIKKEIL---FCQQVRSHLHM-FILIGD--DQAHKQLPSTLFLR
LLQLAIACTDRYEPWDQDSLVTVAQHHLKGA-QSPPLDNDSLRFPDIQASVPSVAKAMAL
IHLSAASYQGHLSPELPLVTPKTFLDFL

ENSGT00910000144015_1_Linker_6_7 (3329, 3453)

DTFVLQRQWMTLHIKNRAQRIQNALENLKMLI
EKHSAHTTLVFNLEEQLKGSHKS------------LGRLNHQIDQSKILYKRQLIECRQQ
ENLIENLTKQRDALRAQYEAFLEQMGKAFLGP

PF12777 // ENSGT00910000144015_1_Domain_7 (3453, 3687)

LSQLQVADFEEIRSYRAPPESVVQVTDA
LCDLFHRETGWASAKQLLCSEDFYQELVFFPKEKMTDAEMIKLNLALKAPGMSDADLRAV
SIPIASLAAWLWAVLCYGLAQRRGLPTGLLLRQVEATLAREQARLGQYQFQAQELLEHSL
ALSKNLENAQTSHKRVVENLGQAQCGKHHKWPVEAALLTPMHSWTTELQKLKGHSSTVLG
DALLCSAAINYLGPFPPVRRQELLDKWLALCRGCQ---EPLGPDDVAQALKQMQKSVATL
-PKNPLLSTRSPFSLVSLLSSESEQFQWDRDMKPQAKSARLAALLLRSRTHYFSCRWPLL
LDPGNEALIWLKPLPLEERNK---------------------KESKEENMED-EDDDSDE
CDKTKEQKAEEK-RIKETKEKKEGQQEQE----------------------EKEQQDEKG
TQSPPPPDLQVFSGASPEL--GPQLQEAAAHGLPVLLTNME--LGLDCPELQWLLQREQL
SPPQVQPGFCLYLSTAVPLNALEK----GKGLSISPGLNVLDLGVNTEILEERMLREILC
TERPELETHWWDLTVRFLDSWDAAVVVEERLLMMLLLQ--GPRRQRPAKFLRDVVRAQGE
LCRLHAHLEDLEELRLKEVAVWAPYRRVVWHGMTIIKALSSLQNLLPLFHMSPEDCLAAT
KRALNSIKG-EIHRREEVTCRLLQLKRQLTHQLLGSTVATLGLTRVPLVGVLGALALLRV
ARKAPELERLALWPGLAVSSSIGCEKPVPGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGLRTWHECEMLEVLPPFAGLCAS
LAGHASVWQAYLSLSSSVLGPAPG--PGAHPLSLLQKLILWRVLRPECLVSTLATFTTSL
LGRPLDENLSAHTIPFEHTRATQPILILLPPPGHPTATLHHLTVIQKLAARHKQ-----H
LKVIALGSETWDPVSIVISSLRKAMLRGEWLVLENCHLMP----HWPKELLQPLLGLLDG
---VSDLDLELLFAQQANGNVAAVHKDFRLWLTVSAEATASLPAVLTQHSMPVFWDQSLE
LGHVLVDSVELVQQGLSVQP-PSRVLPLLLLHGLLLHRQLYGMKLQAHRGHWSQATLTHV
LQIQDQLWASLSNPSVAMRELVASVFYGGPVGDDKDREVLISLTRACLSSSSGNGAQPHT
PQYLLATLMPSPELKELDALEECKAQMHLLPTPPEPRICGLSAGSQTWLLRRQSRAILSA
LQRCSPTWVPAARGTS---RRAERRLRQRLAQAKRRLESLQAQLTEITRQEES---GVGF
GELGLSAPLPLEGFLKTEVLELSQLVGALQRDLDCLLQQLKGAPPCAARRCAAVAQALWT
GRLPAPWRPHAPAGPQPPWHWLRQLSRRGQLLLRYLGVG----TQVPERIFHLSAFCHPR
RLLLSLRWEATFAV------VAPTNFLACQTSSSC-----QLPHKRQELI-SPLHFQVAN
SPHPTVPEMGL-LLIGLQLHNAKWDPVAGALQDSSSSQPSPLPPVSVSAQAPAANDLPPR
GGLAVYSCPVYLEGPLGTTRLHRRKVLMHLPLPTKLSPATCIQRRVHVCSPPLS

------------------------------------------------------------
--------------------------------------------------------MVPE
ERRVGLSSDETSSDSLKSW-HSICVL-DSKEQPLACQQKQRQFVKPVTESEQPTALELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHRRPPCPACPFVQAQWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVRYESSDTDNAEEEP
VGRKET------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------VHEDTYHMQQGLQERVQN
CDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISALEEQITS
FVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKAEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVRGYRLRGQYFPRNYKQLEEDLDNNPQIQQALNIQQVLLEGVLCEVQEFCREHHWITGI
YEFLQSWGPQKLEDMRGGPIKNYVTLVSRLNVWQAHVSSMPIELLTKGKLLLLSCHDVQA
EMESKLNSIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGESPIPPRPPPPQPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIMAKLQQLMAAALAELEGLLAKALSGPF
MDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFAEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL
GEFRSYLPLLTKLGSLQPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVVDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALV
AARLESCEAQLWVRRCFPHVHAVSFRSCPTG-EKNTDDWES----SPNTQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMQ
MRKLEVLVNFIRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLRTIAS-SEPSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAVVNSLAQALGRQLVMLPCSPQIE
ARCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTID
-------PTQPQLLGSSFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNV
TKEEPKCQKPRSLAAIEEAALLHALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEP
MTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESVGIQHWIICDGASNAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRLQHQTIAELNHMA
EVLVPATLRFLTRQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAP-
--GPEDLSYSDPVAQ---SFRSSKSSFL-NRSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2781)

QTERLLYVVDLLLSGGQPVLLAGEAATGKSAFV
EVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQA-SPQPGHHQDSKPSLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERERALAQGLVRASVEAWEAVCNR
FMPSPLHPHYHFSLHSVGHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQESE
E---EEEEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVARVSNSRDPS
LTPSI---G--PVSRGMKESISH--KIRQEKGTRASNYRLQVRRSFKTWWQKKPQ-MDLI
SPL--LLPVLLLHPQEKPSDLVFSQELILGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPS
-GSEEAILQCLRDASWHAGMLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
HIGEHL-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-HSVPLDDGSWKYPDLQASIPSVAKAMAL
IHLSASHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLI
KEHGTHANLIFDLEQQLKDSGRS------------LSMFQQQLEQSKLLYKQQLEECRHQ
EN

PF12777 // ENSGT00910000144015_1_Domain_7 (3423, 3687)

LIENLTKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMNDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLTREQARLGYYQFQAQETLEHNL
ALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTELQKLKGRCMTVFG
DTLLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALIWLDPLPLEENRSFAPAPTEGRGKGLM----RNQKRESK-TDMKEEDDESEE
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKEEEKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAAWGLPVLLTNVE--LGLGCEELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
REYPELETRWQDLKIRALDTCKAVEAAEDRLLTMLLFQ--NPKRQKPAKFLRNMVRAQGK
LCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQA
TGKASELERLAFWPGLAASPSTVHSKPVSDVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSSAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQ--GQKQ
LQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKQLLQLLLELLGR
AKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LRHVLTDSVQLAQQVLYMQP-PTQALPLLLLHGLLLHRQLYRTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHT
PQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSA
LQRSSPVWVPESRRGA---QLAERRLRQRLVQVNRRLESLQDLLTHVIRQDES---GARW
SVLGPNARRSLEGVLETEALELSQLVGTLQRDLDCLLQRLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPACPQPPWHWLRQLPRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNLPGSRGSVSS-----QLQYKRLEMNSNPLHFRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAP
ADLTVYSCPVYMGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

------------------------------------------------------------
--------------------------------------------------------MVPE
ERRVGLSSDETSSDSLKSW-HSICVL-DSKEQPLACQQKQRQFVKPVTESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVRYESSDTDNAEEEP
VGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVTTALKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQKALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRTGQGSIYLQRVQRKQLEHKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITS
FVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKAEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGTL
EVRGYRLRGQYFPRNNKQLEEDLDNNPQIQQALNIQQVLLEGVLCEVREFCREHHWITGI
YEFLQSWGPQKLEDMRGSPIKNYVTLVSRLNVWQARVSSMPIELLTKGRLLLLSCHDVQA
EMESKLNSIRKDILAHVQNECWNLSQQLMTELTDFMHIFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGESPIPPCPPPPQPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIMPKLQQLMAAALAELEGLLAKALSGPF
MDPTQDQRSTEHQLVSLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRIL
GEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLAYPLLEFADR--I
NQVWQNENERIHAQETIRRLQRYWEVRQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVSFRSCPTG-EKNTDDWES----SPNTQTQVEALAVLG
AGGEEVKLQGPLLLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTIAS-SEPSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTID
-------PTQPQLLGSSFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNV
TKEEPKCQKPRSLAAIEEAALLHALLRSPLFSILNGLHLHNLQGLLCALFPSASQVLAEP
MTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESIGIQHWIICDGASNAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADTTGISPTVVGCCALVWCGGEQTWQCILSALMASLPYEYHLQHRTVAELNHMA
EVLVPATLRFLTCQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAP-
--GPEDLSYSDPVAQ---SFRSSKSSFL-NRSQVDSDDVPNKCREHLLAVSSFLFAVIWG
FGAH--------------LPS-RF-WPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2783)

QTERLLYVVDLLLSGGQPVLLAGEAATGKSAFV
EVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQA-SPQPGHHQDSKPSLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCEHPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERERALARGLVRASVEAWEAVCNC
FMPSPLHPHYHFSLHSVSHLLSSLQLLPNRIGSRGFVDYPNHQEHLRRVSGLRGTCLTVM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQHLGKDHQESE
E---E-EEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVARVSNSRDPS
LTPST---G--PVRRGMKESISH--KIRQEKGTGASNYRLQVRRSFKTWWQKKPQ-MDLI
SPL--LLPVLLLHPQEKPSDLVFSQELILGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPS
-GSEEAILQCLRDASWHAGMLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
RIGEHL-PRENPGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-QSVPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRIQHALENLRMLT
KEHGTHANLIFDLEQQLKDSGKS------------LSMFQQQLEQSKLLHKQQLEECRH

PF12777 // ENSGT00910000144015_1_Domain_7 (3420, 3687)

Q
ENLIENLARQRDALQAQQEAFLEQMSKAFLEPLSQLQMADFEEIRSYRAPPESVVRVTDA
MCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMNDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLTREQARLGYYQFQAQETLEHNL
ALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFG
DTLLCSAAIVYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKRKQKSVSVP
-PKNPLLATHAPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALIWLDPLPLEENRSFAPAPTEGRGKGLM----RNQKRESK-TDMKEEDDESEE
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKEEEETESQGSKPACE
TQLPSLPYLSVLSGADPEL--GSQLQEAAASGLPVLLTNVE--LGLGCEELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----ALGCELLKGLNVLDLGLNMEILEEQMLHEILC
REYPDLETRWQDLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNIVRAQGK
LCQLRAHCEELEGQKLQEMVSWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQA
TGKASELERLALWPGLAASPSTVHSKPVSDVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSSAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQ--GQKQ
LQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQVLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQATLTQV
LQTQDQLWASLSNPRAAVQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHT
PQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLTEGPQAWLLRRQSRALLSA
LQRSSPVWVPESRRGA---QLAERRLRQRLVQVNRRLESLHDLLTHVIRQDES---GAPW
SVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGSVSS-----QLQYKRLEMNSNPLHFRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAP
ADLTVYSCPVYMGGPLGTAKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

------------------------------------------------------------
---MKPHSQTS-PPSLPMPSTSCRPGQTQKPKAWNWHLDPELWARSVRQQLNTCLRFILE
EKE------NPWFYTLQSG-LVGCSC-SGQEHSRDCQMKQ-EDLKAVVESEQRTLLKLLL
SELQSLFSAVMQDGSCEAWRYLHAVLGLLPPYREMLAGQLELLPFLEQLYCWAPKVQARL
ELDLLDAIDKAFPPDSSLLHSSSHVDCSPWMKRFHRGPPCSACPFVKAQWDRQQK-KELA
TWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLPLALATDIPVQYGSRDTEHAEGEP
AGR---KLQVASEAPEEKALKKKS----SRTPVLRSQVKSLLERDWTQKKIHFLYLNVVS
DRHFNPYKLVAVPPDKVNPEHYIFSPFGILHIHPVEGSEAMTLGTWHRDYALWRELQRIP
FFKNCLLRKALTCWKKNVRLCGLHRIQTFLKTHLLLAIPHFGVGMLHISRLLQEFRSVSW
LPKEPDKSYELVDLQKAIAKENHKALRMLCHFLNLCTSILQLIHEDTYQMQQGLQERVQN
WNRIRKGQGSIYLQRTLCRHLEKKLKQAETWLLKLGKFARLIDYMICQNLVSILEDEISS
FIANTLQAPRQNPFLLSQLVFDDNGQLSPMPRVESIIQGLIKSLQSIKTSALKVLQSTDL
RTSRDLLYSE---DNKDQDSNAEFLMPKFHGKASDAVRLFCGPNVGYVWPWKSHAITDVL
EVRGHKLRGQFLNPNYDHVQEDLDKNAGIQQALAVQQALLEDMRQEVQEFCNKHKWVEGI
YEFLKAWSSQKLEDLRGSPINNYINLVIQLKKWQERVSNMSVELLTKGKLLFLSGHDVQE
ELGSKLNNMRKNILEQAQNECWSRNQQLMTELTEFLRVFQTISSDIHAIAQCSQKLNEAN
EQYCQLEERVEYVRSLHDLIRNHCTLFIAENETLDIA-----------------------
-------LLDLWEAFQFERSQVSEFLLSKQHAIVPRLQQLMAAALAELEGLLAKALSGPF
MDPSQEQRSTEQQLGALEHQFLNILNNFNALCNAYCTFTGYKKPMSPPASGNRPIVL

PF08393 // ENSGT00910000144015_1_Domain_1 (1138, 1600)

QQL
IWRLYRIISENLGEWKCVAFSKFNLSMAREKTDAWLTEAVRLSTALGLQSPVLQRCMRML
EEFRAYLPLLIKLGNLQLQDLNTQSLLRALGLGSLRSLDLLTLGQMLNYPLLEFAER--I
NQVWQYDKERIHAQEILQQMQQYWEGRQLRLLNFILHVPYKPPTSERSKRP---ALRSPQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGQLHKIALEWVAIMYGLG---
ALLEVWVAFQQKWIFLNKVLHEMKIEFPAPELNARFKAMDDQYRTLMRISVADPMVLSLI
-LPNTKRSPYFQGQHLQQMLKAGSGELEAIIMALEDVLYGVCANFPRLFFLSDSELVALL
AAPLDTCEAQLWAQRCFPYIKAVNFRSKSTK-KKI--N-QD----SSSSTETAETIAVLA
AGGEEVKLQEPLPLHPDLPKWLASLEKCLRLIIVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLIKALKA---
MPQQRQMP----MEVYVQHWLDAVQVFPWQCILVAEEVVWRAEMEEALLESRTMHMSSVH
VYNLEVLVQFIRSQRSSQDGQSLPSVRQTSLFSTLLVKAVTHRDIAQLLEKNQVSDLTDF
HWVRQLKYHLGSSHLNLKSPVECLTTIAS-TEPSVSPAACWIDVLGRSFM

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYMGPKL
GPLPSLMHERQVFILLMALDEVAYGAILGRDGLGKAETVNSLAWTLGRQLVIMPCLPQIE
FQCLRNYLNGALQGGAWLLLENVNQLPSSLLSALGQRLDELHHLYAPLYQKASKNISTIN
-------PTKPLLLGAGFFEKHQVSMRLGFGCFLTLHSLGPDMPANLHLLLRPVALAL-P
DLQRVAELNLLGAGVQDASRMASRLSKLFSLERELVSGNLPCRLPLLKQVLEHTIQTLNA
SQ-EKKSQQPYNPAASEEAALLRALLHSPLFSILDGLRLQKLQELLCGIFPNASHVLAEP
VSHRLIKSVVVEELQQLGLFPASNTVTSLEQLSQALSQASGILLLGPAGSGKSTCWRSLF
KIQNRLAAMEHT----STKGFQSVEIVHLYPSVLNSKEYLGWSEGPSWHYGIFPKLLHAA
PYCKSVGSEEPSEKFTGIQQWIICDGAPNHAWTDSVTCLLRDPPQLSLPNGQQIARPLGT
FFLIEVAEAAGMSPTVLGRCALVWCSGEQTWHSMLSVLMASLPHEYHLQQETITEFNYLA
EVLVPSVLRFLTRIGASSQLQVH-GHQAVCPGVAEVTSLVRILSALLDPFLHLFEEEKSY
--NKEDFSGSDLVIQ---NFKSSKP-----RVQSDRVIVNKKQRRHLLAISSFLFAIIWG
FGAH--------------LPS-RH-WPLFDDFMKKSISSLPNYPEPPPSALVFDLHVNLE
DGTLVPFTGQYLSTHVKGNLGSFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2783)

SQTEQLLYVVDLLLSNGQPVLLAGEIATGKSTFV
EVLVKPNYPAIHSPIHPALNSTHLRHLLSRGVHGQTQA-SSIPGHHQDSKGSILFLMEDL
HLAAFDPEKNCQPVLETLRQAMEGTIYAHNTLELQTLQTTVNFLATATVPGYSERPLCPR
LYRLFTVLALNSMTQDTLLSRHVPSIQAWLERFPSVEREHTLARALVRASVEAWEAVCKC
FMPSPLRPHYRFSPHSVSHILGSLQLLPTRMGSRGFAETFHHQEYLRRVSGLRGTRLTIM
MSMRVMVRLWLHEAQRTFCDRLDSDRERSHCAKLLLEVAQNVFCGGPGSESLAKDCEEEE
------VEEEKVPEVESEEEIAQWETL-----SNSDSGSEEEEDPYGLQATTGSFLSESS
LAPFPR--K--SVNKENTENVSQ--MAEQEEDIRDSSSKLQSKT-PKHEWQTAPQ-MDLS
LPL--LLPVLLFYPQESPSDLVFSLELTLGSNFESSN-LYLERQWENLEKQLVASAVRLK
MNSSFSQCPVMVQHVAHLVRVLARPRQHALLLSEFRGTGRYTAIILASSICQAHLHYLSV
-ESEEAIFQCLRDVSWHAGMLNQPVALAVPDGVNVAIFCRLLALATSGSFPDQYTEADLD
NIEEHF-PKENIVNKHAIKRDTILNRFYQQVCNNLHM-FFMVGD--NEAQNQLPPTLFLN
LLQLTIASIERYEPWDQASLVRIAQFRLEND-HSLPLDDGSLKCPDFKHLIPNVANIMAR
IHVSSACYHKHMCPALPLVTPKTFQDFLDMFRQQQQQMILQMRMRASRIQTALKTLRLMV
ERHSTQTNLLSDLETQLKGSYKS------------VGIYQGQLEQSKIMYRQKMVECQHQ
ES

PF12777 // ENSGT00910000144015_1_Domain_7 (3423, 3687)

LIENLVKQHDALKAQQEVFLEQMGKAFVGPLSQLRVADFEEIRSYRAPPESVVKVTDA
LCDLFHQETGWSSAKQLLCTEDFYQELVFFPKEKLTDSELVKLNEALRAPGMSDAALRSV
SIPAANLAVWLWAVLRYGLAQRRGLPTGLLLRQVDATLAREQARLGQFQFQAHDLLEQTR
SLAKRLEAAQVSHNHVVETLNQAQCGNFQKWPMKSALLTPMHMWTTQLQKLQEQAKTVFG
DALLCSAAIIYLGPFPPQRRQELLEKWLSLCQGSE---EALDPDDVAQALRQ--KSVGV-
-PKNPLLPTRTPFSILTLLSYGSEQHQWDRDLKPQAKSARLLGLLLRSHIHFSSSRWPLL
IDPSNQAIMWLNPLPPKKNRSLEPSPKESREKYSV----PNQDSGNNTEDELEDENN-EE
EDEANEQRKEQKAEENKI--EG---------ENEQEVQETEKENEPENSS--SHSSLPSE
TQ-SLPSCLTVLSGTDPEL--GPQLLEAAANGLPVLLTNVE--LSLGCQELQWLLSKKNL
SPPSVQPGFCLFLSTTFPIHALSR----VLGFELLKGLNVLDLGLNMEILEEQMLHEILC
RERPELETRWQDLKIRAADTYEAMKADEEQLLVTLLRQ--NQKRQKPSKFLRKMVRTQAK
ICQLNAQMEELEDQKQEVVALWAPYRPVAYHGMAMVEALSPLQNLLPSFCMTSENWLAVI
RRAIDSMKPYDSYRGEDLPSHLLRLKIHLARQLLTNTVVALGLIQTPLVGAFGALAMLQV
TKKTPKLERLALWPGLSASPSSGHNMQIPGVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLSSRAWEECGALELLPPFAGLCES
LAGQSGVWQDYLSLSSTVLGPAPG--PNSEPLSLFQKLILWRVLRPDCLAGALADLTTSL
LGRPLDENLGAPTMIFEHIQPTQPILILLPPPGHPTATLHPVTVIRKLAANHEK-VPQKH
LHVIALGSEDWDPVSTVVNTLCQAMLQGHWLVLDNCHLMP----FWPRELLQPLQGLLDR
ARVVSDSEL---LAEPESRSVVTVHRDFRLWLIVPTEASTSLPGMLTQSSMPVFWNQSLE
LGRILIDSLD-SQQGLCTQP-LTQTLPLFFLHGILLHRQLYGLKLQAHRGRWSQVTLTRA
LQIQEQLWASLRNPSAALLELTASVLYGGSLGDLEDREALVSLTRTCLNPRNTNWDQPHT
PQYLLATLMPSPELGELDARTDCKAQMHLLPTPPEPRTCGLNEAPQAWLMRRQSRVLLNA
LQKCSSTWVPTVCGGI--AQRKERQLQQRLAQAKKRLVALQALLTNNR--FRSGQCVTPW
AVLGPNARRPLEGFLETEVLELKHLVGTLLRDLDCLLQQLKGGTPCTSSRCAKVARALWA
GRLPQPWRSYALAGPQLPWLWLRQLSRRGHLLIRYLDSGMSENANEPERIFHLSAFHHPG
RLLLALRWEAVLEN-----SVHNPNLPGHQDSISG-----SLPPKWQELSNHPLHIWVEN
GPNPKVPKMGL-LLTGLQLQHAEWDQTDGALQDSFSSQPCPLPPVSVSTQARRGKDAPVS
AGLGMYSCPVYMTGPFGTTKLHSKNILMHLPLPTRLSPDTCIQRRVHVCSPTLT

------------------------------------------------------------
--------------------------------------------------------MVPE
EKRVGLSSDETSSDALKSW-HSICVL-DSKEEPLACQQKRRQFVKPATESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAINQAFPPDSSLLDSASHADCCPQKQRLHHRPPCPACPFVQARWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRKETRSQLDYEVPREKTLQKSSTGFSPETSFLGSQVMTALKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNAEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQKALAKEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRAGQGSIYLQRVQRKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILEEQITS
FVANILQAPRQKPFLSSQLVFDDHDQLSHVPCVENMIQILTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKTEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVHGYRLRGQYFPRNYKQLEEDLNNNPQIQQALNIQQVLLEGVLWEVQEFCREHHWITGI
YEFLQSWVPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPVELLTKGKLLLLSCRDVQT
EMESKLDSIRKDILAQVQNECWSLSQQLMTELTNFMHVFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFRESSIPPRPPPPRPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIIPKLQQLMAAALAELEGLLGKALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSELHHAYVIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTEGWLTEAARMSTTLGLNSPVLQHCMRIL
GEFRSYLPLLAKLGSLQPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIQQLQRYWEVRQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIQKSGDLNKTALEWMAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVVDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVRFKSCPTG-EKNMDDWES----SPNAQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFLRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLGQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTTS-SEHSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHSLYAPLYQEASRNTSTID
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIQTLNV
AKEEPKCQQPRSLAAIEEAALLHALLHSPLFSVLNGLHLHNLRGLLCALFPSASQVLAEA
MTYKLMKALVVEELQQVGLHPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESMGIQHWIICDGASSAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADATGISPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNHMA
EVLVPATFRFLARQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDPHLRLKEEKAP-
--GPEDLSCSDSVAQ---SFRSSKSSFL-NRSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2781)

QTERLLYVVDLLLSRGQPVLLAGEAATGKSVFV
EVLVEPHHPYIYSPIHPAFSSTHLRLLLSRGIQGQTQA-SPQPGHHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERERALARALVRASVEAWEAVCNC
FMPSPLHPHYHFSPHSVSHLLSNLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTRLTIM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQNLGKDHEEDE
------EEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVATGSNSSDPS
LTPSI---G--PVSRGMRESISH--KIRQEKGTRASNYRLQVRRSFKTWWQKAPQ-MDLV
SPL--LLPVLLLHPQEKPSDVVFSQELTLGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQTHFFHLPS
-GSEEDILQCLRDASWRAGLLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
RIEEHF-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-RSLPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALDNLRMLI
KEHGTHANLISDLEQQLKASSKS------------LSMFQQQLEQSKLLYKQQL

PF12777 // ENSGT00910000144015_1_Domain_7 (3415, 3687)

EECRHQ
ENLIEDLAKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKITDSQLIKLHLILKAPGMSDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLIREQARLGYYQFQAQETLENNL
ALAKMVEDAQASHNCVAKTLSQAQRGQYHKWPMKAALLMPMHAWTIQLQKLKGRCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKNPLLATHSPFNILSLLSSASEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALMWLDPLSLAENRCLAPAPTEGRGKGLM----RNQNTESK-MDMKEEDDDSED
SNEAEDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RECPELETRWQNLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNMVRAQGK
LCQLRAHCEELEGQKLQEMVSWAPYRPVVWHGIAMVKALSQLQNLLPLFRMSPEKWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVSGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMGAPTMPFKHSRATQPMLILLPLPGHPTATLHPLTVIQNLAAKYQQ--GQKH
LQVIALGSEVWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLGQPESRNVATVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALFSLTQACLSPSSRNWVQPHT
PQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRVLLSA
LQRSSPVWVPESRGGA---QLAERRLRQRLVQVNRRLESLQDLLTNLVRQDES---GAPK
SVLGPNARRPLEGVLETEALELSRLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADANSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGAVSS-----PLPYKRLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQASPLPPVSISTQAPGTSDLPPP
ADLPVYSCPVYMGGPLGNTKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

------------------------------------------------------------
---MKPHSQTS-PPSLPMPSTSCRPGQTQKPKAWNWHLDPELWARSVRQQLNTCLRISLE
EKK------NPWFYTLQSG-LVGCSC-SGQEHSWDCQMKQ-EDLKAVVESEQRTLLKLLL
SELQSLFSAVMQDGSCEAWRYLHAVLGLLPPYREMLAGQLELLPFLEQLYCWAPKVQARL
ELDLLDAIDKAFPPDSSLLHSSSHVDCGPWMKRFHRGPPCSACPFVKAQWDQQQK-KELA
TWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLPLALATDIPVQYESSDNEQAEGEP
AGR---KLQVASEAPEEKALKKKS----SRTPVLRSQVKSLLERDWTQKKIHFLYLNVVS
DRHFNPYKLVAVPPDKVNPEHYIFSPFGILHIHPVEGSEAMTLGTWHRDCALWRELQRIP
FFKNCLLRKALTCWKKNVRLCGLHRIQTFLKTHLLLAIPHFGAGMLHINRLLQEFRSVSW
LPKEPDRSYELVDLQKAIAKENHKALRVLCHFLNLCTSILQLIHEDTYQMQQGLQERVQN
WNRIRKGQGSIYLQRTLCRHLEKKLKQAETWLLKLGKFARLIDYMICQNLVSILEDEISS
FIANTLQAPRQNPFLLSQLVFDDNGQLSPMPRVESIIQGLIKSLQSIKTSALKVLQSTDL
RTSRDLLYSE---DNKDQDSNAEFLMPKFHGKASDAVRLFCGPNVGYVWPWKSHAITDVL
EVRGHKLRGQFLHPNYDHVQEDLDKNAGIQQALSVQQALLEDMRQEVQEFCNKHKWVEGI
YEFLKAWSSQKLEDLRGSPINNYVNLVIQLKKWQERVSNMSVELLTKGKLLFLSGHDVQE
ELGSKLNNMRKNILEQAQNECWSRNQQLMTELTEFLRVFQTISSDIHAIAQCSQKLNEAN
EQYCQLEERVEYVRSLHDLIRNHCALFIAENETLDIA-----------------------
-------LLDLWEAFQFERSQVSEFLLSKQHAIVPRLQQLMAAALAELEGLLAKALSGPF
MDPSQEQRSTEQQLGALEHQFLNILNNFNALCNAYCTFTGYKKPMSPPASGNRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

LQQR
IWRLYRIISENLGEWKCVAFSKFNLSMAREKTDAWLTEAVRLSTALGLQSPVLQRCMRVL
EEFRAYLPLLIKLGNLQLQDLNTQSLLRALGLGSLQSLDLLTLGQMLNYPLLEFAER--I
NQVWQYNKERIHAQEILQQMQQYWEGRQLRLLNFILHVPYKPPTSERSKRP---ALRSPQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGQLHKIALEWVAIMYGLG---
ALLEVWVAFQQKWIFLNKVLHEMKIEFPAPELNARFKAMDDQYRTLMRISVADPMVLSLI
-LPNTKRSPYFQGQHLQQMLKAGSGELEAIIMALEDVLYGVCANFPRLFFLSDSELVALL
AAPLDTREAQLWAQRCFPHIKAVNFSSKSTK-KKI--N-QD----SSSSTETAETIAVLA
AGGEEVKLQEPLPLHPDLPKWLASLEKCLRFIIVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLIKALKA---
MPQQRQMP----MQVYVQHWLDAVQVFPWQCILVAEEVVWRAEMEEALLESRTMHMSSVH
VHNLEVLVQFIRSQRSSQDRKSLPSVRQTSLFSTLLVKAVTHRDIAQLLEKNQVSDLTDF
HWVRQLKYHLGSSHLNLKSPVQCLTTIAS-TEPSVSPAACWIDVLGRSFM

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYMGPKL
GPLPSLMHERQVFILLMALDEVAYGAILGRNGLGKAETVNSLAWTLGRQLVIMPCLPQIE
FQCLRNYLNGALQSGAWLLLENVNQLPSSLLSALGQRLDELHYLYAPLYQKASKNISTIN
-------PTKPLLLGAGFFEKHQVSMRLGFGCFLTLHSLGPDLPANLHLLLRPVALAL-P
DLQRVAELNLLGAGVQDASRMASRLSKLFSLERELVSGNLPCRLPLLKQVLEHTIQTLNT
SQ-EKKSQQPYDPAASEEAALLRALLHSPLFSILDGLRLQKLQELLCGIFPNASHVLAEP
VSHRLIKSVVVEELQQLGLFPASNTVTSLEQLSQALSRASGILLLGPAGSGKSTCWRSLF
KIQNRLAAMEHT----STKGFQSVEIVHLYPSVLNSKEYLGWSEGPSWHYGIFPKLLHAA
PYCKSVGSEEPSEKFTGIQQWIICDGAPNHAWTDSVTCLLRDPPQLSLPNGQQIARPLGT
FFLIEVAEAAGMSPTVLGRCALVWCSGEQTWHSMLSVLMASLPHEYHLQQETITEFNYLA
EVLVPSVLRFLTRIGASSQLQVH-GHQAVCPGVAEVTSLVRILRALLDPLLHLFEEEKSY
--TKEDFSGSDLVTQ---NFKSSKT-----RVQSDCVNVNKKQRRHLLAISSFLFAIIWS
FGAH--------------LPS-RH-WPLFDDFMKKSISSLPNYPEPPPSALVFDLHVNFE
DGTLVPFTGQYLSTHVKGNLGSFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2783)

SQTEQLLYVVDLLLSNGQPVLLAGEIATGKSAFV
EVLVKPNYPTIHSPIHPALNSTHLRHLLSRGVHGQTQA-SSIPGHHQDSKGSILFLMEDL
HLATFDPEKNCQPVLETLRQAMEGTIYAHNTLELQTLQTTVNFLATATVPGYSERPLCPR
LYRLFTVLALNSMTQDTLLSRHVPSIQAWLERFPSVEREHTLARALVRASVEAWEAVCKC
FMPSPLRPHYRFSPHSVSHILGSLQLLPTRMGSRGFAETFHHQEYLRQVSGLRGTRLTIM
MSMRVMVRLWLHEAQRTFCDRLDSDRERSHCAKLLLEVAQNVFCGGPGSESLAKDCEEEE
------VEEEKVPEVESEEEIAQWETL-----SNSDSGSEEEEDPYGLQATTGSLISENS
LAPFPR--K--SVNKENTENVSQ--MAEQEEDIRDSSSKLQSKT-PKHEWQMAPQ-MDLS
LPL--LLPVLLFYPQESPSDLVFSLELTLGSNFESPN-LYLERQWENLEKQLVATAVRLK
MNSGFSQCPVMVQHVAHLVRVLARPQQHALLLSEFRGTGRYTAIILASSICQAHLHYLSV
-ESEEAIFQCLRDASWHAGMLNQPVALLVPEGVNVAIFCRLLALATSGSFPDQYTEADLD
NIEEHV-PKENIVNKHAIKRDTILNRFYQQVCNNLHM-FFMVGD--NQAQNQLPPTLFLN
LLQLTIASVERYEPWDQASLVRIAQFRLEND-HSLPLDDGSLKYPDFKHLIPNVANIMAR
IHVSSACYHKHMCPALPLVTPKTFQDFLDMFLQQQQQMVLQMRMRASRIQTALKTLRLMV
ERHSTQTSLLTDLETQLKGSYKS------------VGICQGQLEQSKIMYRQKMIECQHQ
ESLIENLVRQHDALMAQQEVFLEQMGKAFVG

PF12777 // ENSGT00910000144015_1_Domain_7 (3452, 3687)

PLSQLRVADFEEIRSYRAPPESVVKVTDA
LCDLFHQETGWSSAKQLLCTEDFYQELVFFPKEKLTDSELVKLNEALRAPGMSDAALRSV
SIPAANLAVWLWAVLRYGLAQRRGLPTGLLLRQVDATLAREQARLGQFQFQAHDLLEQTR
SLAKKLEDAQVSHNRVVETLNKAQCGNFQKWPMKSALLTPMHMWTTQLQKLQEQAKTVFG
DALLCSAAIIYLGPFPPQRRQELLEKWLSLCQGSE---EALDPDDVAQALRQ--KSVGV-
-PKNPLLPTRTPFSILTLLSYGSEQYQWDRDLKPQARSARLLGLLLRSHIHFSSSRWPLL
IDPSNQAIMWLNPLPPKQNRSLEPSPKESREKFYV----TNQDSGDNTEDELEDENN-EE
EDEANEQRKEQKAEENKI--QG---------ENEQDVQETEKENEPESSG--SHSSLPSE
TQ-SLPSCLTVLSGTDPEL--GPQLLEAAANGLPVLLTNVE--LSLGCQELQWLLSKKNL
SPPSVQPGFCLFLSTTFPIHALSR----VLGFELLKGLNVLDLGLNMEILEEQMLHEILC
RERPELETRWQDLKIRAADTYEAMKADEEQLLVTLLRQ--NQKRQKPSKFLRKMVRTQAK
ICQLNAQMEDLEDQKQEVVALWAPYRPVAYHGMAMVEALSPLQNLLPSFCMTSENWLAVI
RKAIDSMKSYDSYHGEDLPSHLLRLKIHLARQLLTNTVVALGLIQTPLVGAFGALAMLQV
TTKTPKLERLALWPGLSASPSSGHNMQIPGVIRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLSSRAWEECGALELLPPFAGLCES
LAGHSGVWQDYLSLSSTVLGPAPG--PNSEPLSLFQKLILWRVLRPDCLAGALADLTTSL
LGRPLDENLGAPTMIFEHIQPTQPILILLPPPGHPTATLHPVTVIRKLAANHEK--PQ-H
LHVIALGSEDWDPVTSVVNTLCQAMLQGHWLVLDNCHLMP----FWPRELLQPLQGLLDR
ARVVSDSEL---LAEPESRSVVTVHRDFRLWLIVPTEASTSLPGMLTQSSMPVFWNQSLE
LGRILIDSLD-SQQGLCTQP-LTQTLPLFFLHGLLLHRQLYGLKLQAHRGRWSQVTLTRA
LQIQEQLWASLRNPSAALLDLTASVLYGGSLGDLEDREALVSLTRTCLNPRNTNWDQPHT
PQYLLATLMPSPELGELDARTDCKAQMHLLPTPPEPRTCGLNEAPQAWLMRRQSRVLLNA
LQKCSSTWVPTVCGGI--AQRKERQLQQRLAQAKKRLVALRALLTNNR--IRSGQCVTPW
AVLGPNARRPLEGFLETEVLELKHLVGTLLCDLDCLLQQLKGGTPCTSSRCAKVAQALWA
GRLPQPWRSHALAGPQLPWLWLRQLSRRGHLLIRYLDSGMSENANKPERIFHLSAFRHPG
RLLLALRWEAVLEN-----SVHNPNLPGHQDSISG-----SLPPKWQELSNHPLHIWVEN
GPNPKVPKMGL-LLTGLQLQHAEWDQTDGALQDSFSSQPCPLPPVSISTQARRDKDAPVS
PGLGMYSCPVYMTGPFGTTKLHSKNILMHLPLPTRLSPDTCIQRRVHVCSPTLT

------------------------------------------------------------
--------------------------------------------------------MVPE
ERRVGLSSDETSSDPLKSW-HYICVL-DSKEQPLVSQQKQRQFLKPATESEQPTVLQLLL
AELRTLFSAVLQDSSPAAWCYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAIVQAFPPDNSLLDSASHADCYPQKRRLHHRPPCPACPFVHAQWSGQQVKEELA
TWLQPLTLPELQCCLGIIGAEVALEETVWLDGLSLLPLALATDIPVQYESGDIDNAEEEP
VGRKETRSQLDYDVHREEAFQKRSTGFSPETSFQNTQVMTVVNMERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPNKVNPEHYVFSPFGILHVHPVEGSETMTLGTWHHQCVLWQQLQLIP
FFKYCLLRKSLTCWKKNVRLQGLHRLQNFLENHLLLAVPHFGAGLLHISRLLQELRSASW
LPQELDQCYELLDLQKVLAKEKHKAVRLLHRCLNLCTSIRRQVHEDTYHMQQGLQERVQN
CSRIRTGQGSIYLQRVQRKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILEEEITS
FVANMLQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQILTGGLQSVKASALQVIQSADL
KTSLDSLYSE--EEDEEENSKTEFLMPKFHGQPSNAVSIFCGPNVGLVWPWKSHPIAGIL
EVRGYRLRGQYLPHSYKQLEEDLDNNPQIQQALNIQWVLLEGMLREVQEFCREHHWITGI
YEFLQSWGPQKLEDMRGCPIKNYVMLVSRLNVWQARVSNMPVELLTKGKLLLLSCHDVQA
EMESKLNSIREDILAQVQNECWSRSQQLMTELTDFMHVFQTINSDIHAIAQCTQKLNDAN
EKYIELEERMEYIRALHELIRNHFSLFSAENEALDISL----------------------
--------LDMWDAFQFEKSQASEFLLNKRHSIMPKLQQLMAAALAELEGLLGRALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSEVHLAYAIFTGDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFGKFSLAMAQEKTEGWLTEAARMSSTLGLHSPVLQHCMRML
GEFRSCLPLLAKLGSLHPQSLNCQGLLRALGLGSHQTIELLTLGKLLTYPLLEFADR--I
NQVWQGENERIHAQETIRRLQQYWEGRQLRLLNFILHVPYEPPASEHSKRQ---MLRSSQ
WKVVSKDSGTFILADYSNLKDSIQESIQVLVKILAIQKSGDLNKIALEWVAIMHGLG---
ALLEVWVTFQQKWIFLNKVLHEMKIQFPSADLSSRFKAMDDQYRTLMHISLADPMVLSLV
-VPNAKRSPYFQGQQLQQLLQAGSVELEDIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQRWVRRCFPHVRAVSFKSHPTG-EKNRDDWES----SPNTQTQVEALAVLG
VGGEEVKLQSPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAAHLAQGPSLAEALKQ---
LPKQNQLY----LQPYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFLRAQRASQGKQPLPSVRQTSLLSALLVMAVTHRDIAQLLEKHKVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTAS-SEPSQSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPKGVGKRAIVNSLAQALGRQLVILPCSPQIE
TQCLSNYLNGALQGGAWLLLEAVHQLPPGLLSALGQRLAELHHLYAPLYQEASRNTSTID
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLELRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFRMATRLSKFFSLERELVSGPLPCRLPLLKQILKDTIQTLNV
TKEEPESQQPRSLAATEEAALLHALLRSPLFSILNGPYLHNLRELLCVLFPSASQVQAEP
MTHRLMKPLVVEELQQVGLHPSPDVLGSLEQLSQALSQASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLNPQEFLGWLEGPCWHHGIFPKVLCAA
SQCKNMGQKRQTEKSMAIQHWIICDGASSAAWLDSITCLLSELPQLSLPNGQQIERPPST
FLLMEVTDATGMSPTVVGCCALVWCGGEQTWQCILSALMASLPSEYRLQHQTVTELNHLA
EVLVPATFRFLTGQGVSSLLQVH-GQQAVCPGVAEVTSMARILHSLLDPHLHLE-EKAP-
--GPEDLSCSDPVAQ---SFRSSKRIFL-NQSQVDSDDVPNKSREHLLAVSSFLFALIWG
YGGACECVINGSIVPVRHFCL-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2783)

QTERLLYVVDLLLSAGQPVLLAGEAATGKSAFV
EVLVEPHHPYIYSPIHPAFSSTHLRLLLSRGIQGQNQA-SPQPGQHRDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTINYLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLSRHVPIIQAWLERFPSVERETALAQALVRASVEAWEAVCNC
FMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNLQEHLRRVTGLRGTRLTAM
MATRNMVRLWLHEAQRTFCDRLDSPRERSYCAQLLLGVAQSVFCCRPGPQNLGKGHEEGE
E---DEEEKEKVPEVESEGELAQWEDF-----SNSNSETEEEEDTYGLQVPRGSNFSDPS
LSSST---G--PVSRGMMESISH--KIRQEKGTRASNYKVQVKRSFKTWWQKAPK-MDLV
SPL--LLPVLLLHPQEKPSDLVFSQELILGSNSENPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLMLSRALGTGCHTAITLASSICQAHFFHLPS
-GSEEAILQCLRDASWHAGMLSQTVALLVPSGVDLTTLHRLLALATSGSFPDQYTEADLD
HIEDHL-PRENLGVKHNIEKEMVLQRFYQQVCSHLHL-FFLIGD--KQAHQQLPTTLFLR
LLQLATASIDRYEPWDQAALVQVAQHHLEGA-QSLPLDDGSWKYPDLQPSIPSVAKAMAL
IHLSATLYHEHLCPALPLVTPKTFLDFLDTFLMLQQQMILKIKNKAQRVQNALGNLRMLI
MEHSTHADLIFDLEQQLKASFKS------------LSMFQQQLEQSKLLYKQQLEECRHQ
EKLIKN

PF12777 // ENSGT00910000144015_1_Domain_7 (3427, 3687)

LAKQRDALQAQQVAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVQVTNA
LCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKMTDSELIKLHLTLKAPGMSDAALRAV
SLPAASLAAWLWAVLHYGLARCRGLPTGLLLQQVEATLTREQARLGYYQFQAQETLEHNL
TLAKMVEDAQDSHNCVAKTLSQAQYGQHHKWPMKAALHTPIHTWTTQLQKLKGHCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCGGFQ---EPLGPDDVAQALKQKQKSVSMP
-PKNPLLATRSPFSILSLLSSESEQHQWDQNLKPEAKSARLAGLLLRSPTHYRSCRWPLL
LDPSNQALMWLDPLPEEENRCFAPAPAEGRGKGLL----RNQNRESK-TDMKKKADDSEE
SNEAKDQTKEQKAEERKNEQE---------K------EPEEKEEKEEEKTESQGSKPASA
TQLPSLPYLSVLSGADPEL--GSQLQEAAAHGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCALEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RECPELETHWQDLKIRALDACKAVETAEEQLLLMLLFQ--NPKLQKPAKFLRNMVRAQAK
LCQLRAHYEEIEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFRMSLENWLAAA
KQALDSMKPREINHGEDLASHLLQLRAHLTRHLLDSTVTALGCTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVPGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPRAWRECEMLELLPPFSGLCAS
LAGHSNAWQSYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLADALADFTTSL
LGQPLNANMGAPTMPFKHSQATQPILILLPPPGHPTATLHPLTAIQKLAAKHQQ--GQKH
LQVIALGSETWDPVSVVVSTVYQAMCEGNWLVLDNCHLMP----HWPKELLQLLLELLGR
ARVIADLKSEQLLGQPESRNVATVHRDFRLWLIVPAEASASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-LTQALPLLLLHGLLLHRQLYGVRLQAHRGRWSQVTLTRV
LQTQDQLWASLSNPSAAMQELTASVFYGGPLGDTEDREALISLIQACLSPSDRSRVQPHT
PQSLLAMLMPLPELRELDAMAECKAQMHLLRSPPEPRLCGLNEGPQAWLLRRQSRALLSA
LQQSSPMWVPATHGGA---QLADRRLRQRLVQASRRLESLQDLLIHPVRQNES---GAPW
SVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALRT
GRLPSPWRPHAPAGSQPPWHWLRQLSRRGQLLVRYLGVGADAGSDVPEHVFHLSAFRHPR
RLLLALQREAALDQ-----NVPSSNLAGSRGSFSS-----QLPYKRLEMNSNLLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPTTGALQDSPSSQPNPLPPVSISTQAPGTSDQPPP
EGLTVYSCPVYMAGPLGTTKLQSRNIVMHLPLPTKLSPSTCVQRRVHVCSPPLP

------------------------------------------------------------
--------------------------------------------------------MVPE
EKRVGLSSDETSSDALKSW-HSLCVL-DSKEEPLACQQKQRQFVKPATESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDFLPFLEQLYCWAPWVQTHL
HLDLLGAINQAFPPDSSLLDSASHADCCPQKQRLHHRPPCPACPFVQAWWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRKETRSQLDYEVPREKTLQKSSTGFSPETSFLGSQVMTTLKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYYLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDQCCELLDLQKALAKEKHKALRLLHHCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRAGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILQEQITS
FVANILQAPRQKPFLSSQLVFDDHDQLSHVPRVENMIQILTGGLQSVKISALQVVQSADL
KTSSDSLYSE--EEDEEEDSKTEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVHGYRLRGQYFPRNYKQLEEDLNNNPQIQQALNIQQVLLEGVLWEVQEFCGEHHWITGI
YEFLQSWVPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPIELLTKGKLLLLSCRDVQT
EMESKLDSIRKDILAQVQNECWSLSQKLMTELTDFMHVFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGKSPIPPRPPPPRPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIIPKLQQLMAAALAELEGLLGKALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTEGWLTEAARMSTTLGLNSPVLQHCMRIL
GEFRSYLPLLAKLGSLQPQSLNSQCLLRALGLGSLQTIELLTLGQLLTYPLLEFTDR--I
NQVWQNENERIHAQETIRQLQRYWEVRQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIQKSGDLNKIALEWMAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHGVRFKSCPTG-EKNMDDWES----SPNAQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVTARLAQGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQTFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSVH
MRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTAS-SEHSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIQ
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHRLYAPLYQEASRNTSTID
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLEHELVSGPLPCRLPLLKQILEDTIQTLNV
TKEEPKCQQPRSLAAIEEAALLHALLRSPLFSVLSGLHLHNLRGLLCVLFPSASQVLAEA
MSYKLMRALVVEELQQVGLHPSPDILRSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESMGIQHWIICDGASSSAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADATGMSPTVVGCCAVVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNHMA
EVLVPATFRFLARQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDAHLRLKEEKAP-
--GPEDLSCSDPVAQ---SFRSSKSSFL-NQSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2782)

QTERLLYVVDLLLSRGQPVLLAGEAATGKSVFV
EVLVEPHHPYIYSPIHPALSSTHLRLLLSRGIQGQTQA-SPPPGHHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERECALARALVRASVEAWEAVCNC
FMPSPLHPHYHFSLHSVSHLLSNLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTRLTIM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQNLGKDHEEDE
------EEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVATSSNSSDPS
LTPSI---G--PVSRGMRESISH--KIRQEKGTRASNYRLQVRRSFKTRWQKAPQ-MDLV
SPL--LLPVLLLHPQEKPSDVVFSQELTLGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSSHLAQCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPS
-GSEEAILQCLRDASWHAGLLSQPVALLVPSGVDLTTLHRLLALATSGSFPGEYTEADLD
RIEEHF-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-RSLPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQWVQNALENLRMLI
NEHGTHANLISDLEQQLKASSKS------------LSMFQQQLEQSKLLYKQQLEE

PF12777 // ENSGT00910000144015_1_Domain_7 (3417, 3687)

CRHQ
ENLIENLAKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMSDVALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLIREQARLGYYQFQAQETLENNL
ALAKMVEDAQASHNCVAKTLNQAQRGQYHKWPMKAALLMPMHAWTIQLQKLKGRCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKNPLLATHSPFSILSLLSSASEQYQWDRNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALIWLDPLPLAENRCLAPAPTEGRGKGLM----RNQNTESK-MDMKEEDDDSEE
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMKILEEQMLHEILC
RECPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNMVRAQGK
LCQLRAHYEELEGQKLQEMVSWAPYRPVVWHGIAMVKALSQLQNLLPLFRMSPEKWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVSGVTRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMGAPTLPFKHSRATQPMLILLPLPGHPTATLHPLTVIQNLAAKYQQ--GQKH
LQVIALGSEVWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLGQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPHAAMQELAASVFYGGPLGDTEDREALFSLTQACLSPSSRNWVQPHT
PQSLLAMLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRLLLSA
LQRSSPVWVPETRGGA---QLAERRLRQRLVQVNRRLESLQDLLTNLVRQDES---GAPK
SVLGPNARRPLEGVLETEALELSRLVGTLQRDLDCLLQQLKGAPPCPSSRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVSYLGLGADANSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGAVSS-----PLPYKRLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPPP
ADLSVYSCPVYMGGPLGNTKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

------------------------------------------------------------
---MIPHKQIG-LSCFPLPPIPLRTGEAQQPGAWNWQSDPKLWAKSVRQQLDAQLLLVQE
EKRVGLTPEEATPDPLK-----------PSQQPWDCKRKEKKFLKAVS---EPTLLQLLL
NELRNLFSAVLQNGRPAAWRYLHAVLGLLPPYCGLLCGHLDLLPFLEQLYRWAPWVQSQL
QLDLLDAINQAFPPDTSLLESSSHADCHPQKQRFHHGPPGPACPFVQARWGGQQVEEELA
TWLRPLTLPELQHCLGIVGAEVALQETRWLDGLGLLPLALATDIPVQYERGGTNNAEEEP
AER-RTRSQLDYEVSGEKTLQKRSTD-LPKTSSLGGQVMTILQTERHLKKIHFLYLNVAP
NRYFRPYSLVVVPPNKVNPEHYIFSPFGILHVHPVEGSETMTLGSWHRHSVLWQQLQFIP
FFKYCLLRKALTCWKKSVKLQGLHRRQTFLGNHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQEPDKCYELLELQQALAKENHKALRLLLRCLRLCTAILQRVHEDTYHMLQGLQERIEC
CKRIRTGQGSIYLQRIQHQELEQKLKQAETWLLQLGQLARLVDYMICQNLVSIVEEEIAS
FVANILQAPRQNPLLITQLVFDSCGQLSHLPCTKEMIQVLSEGLQSVKAAALKIMRSADL
KTSCDTLCSQGTPLEDEEDSNMNFLTPKFQGQPSEAVRIFCGQDIGLVWPWKFFPSTGTL
EVRGYRLRGQYYPRNYTHLQKDLDNNPRIQQALIILQTLHEAMLQEVQEFCRGQNWMTGI
YEFLEAWGPEKLEAMRGCPVKDYVMLVSRLNVWQSLVSNMPVELLTKGKLLLLSCHELQA
EMESRLGNVRKDILAQVQNECWSRSQKLMTELTDFTNVFQNINSDVHAIARCSQKLNEAS
EKYIVLEERVEYIRSLHELIRNHFSLFSTENEALDISVRGQFIPPTLP------------
--VPAPTLLDVWEAFQFERSQASAFLLSKRHTIVPKLQQLMTAALVELEGLLEKALSDPF
LDPEQEQRSTENQLISMERQFQITASHLSELHHAYSTFTGDESPVPLPTCGAHP

PF08393 // ENSGT00910000144015_1_Domain_0 (1135, 1293)

IMQQQR
IWHLYRIISENISEWKCMAFAKFNLAMAQEKTDGWLTEAARMSATLGLHSPVLQRCMRIL
EEFRNQLPLLTKLSSLHLQNSNCQGLLRALGLGSFSNMEVLTLGCLLSCPLLEFSDR--I
NQIWQYENERIHAQETLWRLQHSWEARQLRLL

ENSGT00910000144015_1_Linker_0_1 (1293, 1326)

NFILHVPYEPTASERSKRH---MLRSPQ
WEVVG

PF08393 // ENSGT00910000144015_1_Domain_1 (1326, 1603)

KDSGTFILSDYRSLQDSIQESLQILFKILAIQKSGDLYKIALEWVTIMRGLG---
SLLEVWVTFQQKWIFLNKVLYEMKIQFPNSDLGSRFKAVDDQYRTLMRISVADPQVLSLI
-MPGAKRNPYFQGQQLQQLLQASSVELEGIIMALESVLYEVRAHFPRLFFLSDSELVALL
AAPLESGEAQKWVQRCFPHVHAVSFKSSLRNEQKNIGDPKS----SPSTENQVEALAVLG
AEGEEMTLQEPLPLHLDLPKWLASLEKCLRLTLVHRLQDCVAALLALGLSLDEDSKQ---
VPLQGQSP----LNLNVHHWLKLVQTFPWQCMLVAEEVVWRAEMEEALLDGKTLAIVPMH
VRKLEVLVQFVRAQRASQGGQSPPSARQASLLSALLALAVTHRDIAQLLQQHQVSDLKDF
HWARQLKYHLGSPHTVPQSPLQSLKTITS-TGPSLSQAACWVDMLGHSFLYNYEYLGPRL
GPIPSLLPEQPVLVLLLALEEVACGTLLGPDGVGKRAMVINLAQALGRHLVMMPCLPQIE
ARCLSNYLNGALQSGAWLFLEAVQHLPPGLLSALGQRLAELHHLYAPLYRKASQSTSTTD
-------PTESQLLGSGFFEKRHVCIRLGYGCLLALRALSLAVPANLRLLLRPVALVL-P
DLQQVAELTLLGAGVREASRMATRLSRFFSLEHELVSGSLPCRLLLLRQVLEDTVQTLNM
TMKVSSSQQLGRIAAIEEAALLRALLHSPLFNIIDEQRLHSLQELLCGLFPNASKVLAEP
MAPRLMKPLLVEELKQVGLHPSPDILESLEQLSQALRRASGILLLGSAGSGKTTCWHSLF
KIQNRLAAMEDT----STCDFQPVEITHLYPSVLTSQEYLGWLEGSCWHHGIFPRLLRAA
TQCEFMVPKVKTQKSVGIQHWLICDGAPAASWLDSITYLLSDPPQLSLPNGQQIVRPPGT
FLLMEVADTTGLSPTVVSHCALVWCGGMQTWQCMLSALMAALPHEYRLQPQTVTELNRLA
EILVPALFRFLTRQDASSVLQVH-GQQPVCPGVAEITSLARILRGLLDTYLRLDEETA-H
--GPEDLSSNDPVAQ---SFQSSKSNSLNNQFQADHDDVHNKRRKHLLAVSSFLFALIWG
FGAH--------------LPSSRV-WPLFDTFMRSSLSCLSNYPELPPSALVFDLHICLE
DGTLIPFTGQYLNSRIKGTLGNFIPSPQTERLLYVVDLLLSWRQPVLLAGEAATGKSAFV
EVLIEPNHPYTYSPIHPAFSSIHLRLLLSRGIQSQAQA-SLYPGLHQDSKGF-LFLLEDL
HMAASDLEKSCQPVLETLRQAIDGTVYTHTTVELQALQPIVNFIATVTVPGCCERPLCPR
LFRHFTVLALGSMTRATLLSRHTPGIQAWLERFPSVEREGILAKALVQASVDAWEAVSSC
FMPSPLHPHYRFSPHSVSHLLGSLQLLPTRVSSRGFVDCPNHQEYLRRVSGLRGTRLTIM
IAMRNMVRLWLHEAQRTFCDRLDSPRERSHCAKLLLEVAQCVFCWGPGPQLLGNGHEEEE
-------EEEKIPEVESEGELAQWEDL-----SNSSSETEEEEDPYGLQVPTGSHYSNSS
LAPTSVLTR--SVSRETIESTSQ--NTSLEEGTM-TSYKLQKKR-SKSWWQKIPR-MDLV
TPL--LPSVLLLHPQEKPSDLIFSQELILGSNSESPN-LYLERQWESLEGQLVTSVTQLK
LSPHFALCRSMAQHVTRLVRVLARPREHGLLLSGTLGTGRRTAITLATSIFQVRLFHLPS
-VSEEAIVQCLWDASWHAGMLCKPVALVVPEDVDLTTLYRLLALVTSGSFPDQYTEADLD
SIEEQF-PRDNLGIKQNIKKEMVLQRYYQQVCSHLHL-FILVSH--DQARHQLPSTLFLR
LLQLAITSIDHYEPWDQAALVTVAQHHLKSV-QSLPLNDSALKCPELQSSIPSVAKAMAL
IHLSAASYNEHLCPLLPLITPKTFLDLLDTFLLIQQQMILQTRHKAQQIQNALENLEMLI
EQYTAHAKLIFSLQQELKGSRKA------------LHFPKVNYYKELLIWFRRLKKKKVQ
GDLRENIMPQNSPLRKQTKGVGFQMGKAFLGPLSQLQVADFEELRSYRAPPESVVKVTNA
LCDLFHCEPGWSSAKQLLCTEDFYQELVFFPKEKMTDSELIKLNTALKGPGMSDKAIRAV
SIPAASLAAWLWAVLRYGLAQRRGLPTSLLLQQVEATLAREQARLGCYQFQAQEILEHSL
VLSKKMEEAQASHIRVMESLNRMQCGRYSKWPIKAALLTPMHSWTTRLQKLKEHCMTVCG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALDPDDMAQALTQKQKSVTM-
-PKKPLLPTRSPFSILSLLSSDSEQQQWDRDMKPQAKSARLVGLLLRSHTHYRSCRWPLL
LDPSNQALTWLNPVSLEENQCSALSPSENRGIGLM----RNQEEKGNEDDSEEEDDGNGT
SEEAEVK-------LREQKAEEKKLKEAEEKEKKIEQEQEKTEQAKEGNRRENKSKVALW
TQSLPVPYLTVLSGADPEL--GPRLQEAASSGLPVLLTNME--RGLGCQELKWLLQREQL
SPPQVQPGFCLYLSTTLPLSSLNK----VLDCNLLKRLNVLDLGLNMEVLEEQMLHEIMC
VECPELETRWQDIKIRTLDTCEAMESAEERLLAMLLVQ--NLEQQKPAKFLRAMVRAQAG
LCQLRAQYEELEDMRLQEVALWAPYRRVVRYGMALVQALSPLQNLLPLFRMSPDKWLAAT
KKALNSMKQREIQPGEDLASHLLQLRAQLTRQLLDSTVAALGLTQVPLVGALGALALLRV
TGKASELERLALWPGLAASPSTGQSKPVLGMARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 4992)

AWIGLKAWQECGMLELLPPFAGLRAS
LAGHSNVWQAYLSLSSTVLGPAPG--PSPDPLSLLQKLILWRVLRPERLAGALADFTTSL
LGRPLDETLDASTMLLEHSQATQPMLVLLPPPGHPTATLHPLTVIQKLAAKHEQ--GQKH
LQVIALGSEAWDPVPGVVNTLCQAMHNGYWMVLDNCHLMP----HWPKSLLQPLLDLFDG
AKVISDMESELHVAQPASRNLATVHRDFRLWFIASAEAIASLPAMLTQYSMPVFWDKSLE
LGRVLIDSLGVAQQELCVQP-LTQALPLLLLHGLLLHRQLYGPRLQAHKGRWSEVTLTQV
LQTHDQLWANFSNPSVAMQELAASVFYGGPLRDTEDREALRSLTQACLSPSSWSWTHPHT
PQYLLATLMPGPDLGELDALAECKAQMHLLPTPPEPRICGLSAGPQAWLLRHQSRALLRA
LQRCSPAWLPEGRRGA---WRAERRLRHRLAQAARRLESLQSLLAGTTHQREF---SAEW
AVLGPKARGPLQGFLETEALELRELVDILQRDLDCLSQQLKGAPPCASRRCVAVAQALWT
GRLPPPWRPHAPAGSQPPWHWLRQLSRRGQLLTRYLVSG--AGTVVSERVFHLSAFRRPR
RLLLALRWEAALATAIPDQYLPSRNLPGNRDSDFC-----QAPQKRLELNSNPLRLWVEN
GPNPPVPEMGL-LLTGLQLLHAEWDPIAGVLQDSSSSQPSPLPLVSVSTQAQSTKDQPPP
GGLAVYSCPVYMEGPLGITKLHSRNILMHLPLPTKLSLATCAQRRVHVCSSPLP

------------------------------------------------------------
---MIPHPQTS-PSSLPTPSTCRRPGETQQPKAWNWHLNPELWARSVRQQLNTCLRFILE
DS-------KPSFSTLESG-LTECSC-SPQGHSWDCIKKQ-ELLKAVVESEQRTSLELLL
SELRSLLSAVLQDGSCEAWRYLYAVLGLLPPYREMLVGQLDLLPLLEQLYCCAPKVQSQL
HLDLLDAIDKVFPPDRSLLHSSSHVDCHPWTKRSHRRPPCWPCPFVKALWSGQQK-RELA
TWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLPLALATDIPVQYESGDADYEEGES
SGR---KSQLASESPEEKAFKKKS----SKTSLLTSRMKSLLKIDRYQRKIHFLYLNVPR
SCPMLPAVFSLH-------ASFSF-------------------ALFH---SSWPCFRNMR
TY---CHSPLTYSWKKNVRLYGLHRIQTLLKNNLLLAIPHFGAGMLHISRLLQEFRSVSW
LPKEPDKSYELLDLQRTLAKENHKALRMFCRFLNFCTSVLQLVHEDTYQMQQGLQERVKN
WNRIRKGQGSLYLQRVLCRHLEKKLKQAETWLLKLGKFARLIDYIICQNLISILENEITS
FVANTLQAPRQNPFLLSQLVFDDNGQLSPMPRVETIIQSLTNGLQSIKTSALKVLQSTDR
RTSRDPLYSE---DDKDQDSNVEFQMPQFHGQPSDAVQLFCGPNVGFVWPWKSQAITDVL
EVRGHRLRGQYLHPNYNHVQEDLDNSAKIQQALAVQQALLEDMLQEVQEFCNEHKWVECI
YKFLKAWDPQKLEDLRGSPIKDYVILVGQMEEWQERVSNMPVQLLTKGKLLLLSGHDVQA
ELESKLNSMRKSIFAQVQSECWSRNQRLMTELTDYLRVFQTISSDIHAIAQCSQKLNEAN
EQYSQLEERVEYVRSLHELIRNHCGLFIAENETLDIA-----------------------
-------LLDVWESFQFERSQASEFLLSKRHSIVPKLQQMMAVALAELEGLLSKALSGPF
MDPSQEQRSTEHQLSVLEHQFSKTLNNFNDLHYAYITFTGDDSTMSPPTCGSRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

QQQR
IWRLYRIITENFSEWKCMAFTKFSLSMAREKTDAWLTEAARLSTTLGLHSPVIQRCMRLL
EEFRNYLPLLNKLGTLQLQNFNCQSLLRMLGLSGLQSFDLLTLGQLLNCPLLEFADR--I
NQVWQYNKERIHAQEILQQMQQYWEGRQLRLLNFILHVPYKPPASERSKKQ---AFRSPQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGELHKMALEWMNIMHGLG---
ALLEVWVAFQQKWIFLNKVLHEMEIQFPDAELNARFKAMDDQYRTLMRISVADPMVLSLI
-VPNSKRSPYFQGQHLQQLLKAGSVELEAIVMALADVLYGVCAHFPRLFFLSDSELVALL
AAPLEACEAQSWAQRCFPHIKAVNFRSAPHE-EKSKNDQES----SSGTQGQVETIAVLG
AFGEKVKLQDPLPLQPDLPKWLASLEKCLRFVIVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLVKALEA---
LPQQRQAP----MQLYVQHWLDAIQVFPWQCILVAEEVVWRAEMEEVLFEWGTLRTVSIH
VHKLEVLVQFIRAQRSSQGEQPLPSVLQTSLFSTLLVMTVTHRDIAQLLEKHQVRDLTDF
HWVRQLKYHLGSSHLNSNSPLQCLKTIAS-AEPSLSPAACWIDVLGRSFI

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPKL
GPLPSLMHEREVLVLLLALEEVACGTLLGRDGLGKTEMVTSLAWTLGRQLVMMPCLPQIE
FRCLSNYLNGALQGGAWLLLENIHQLPASLLSALGQRLDELHHLYAPLCQKASKNISTIN
-------PTKAPFVGAGFFEKHDVSMRLGYGCFLTLNVLRRDVPANLHLLLRPVAFAL-P
DLQRVAELNLLCAGVQDASRMAIRLSRLFSLERELVSGTLPCRLPLLKQVLKDTIQTLNA
TKEENNSQQPHNSVAPEEAALLHALLHSPLFSILDGFRLQKLKELLCGIFPNASHVLAEP
VTPRLMRSVVVEELQQLGLLPTPNTLMSLEQLSQALSQASGILLLGPAGSGKSTCWKSLL
KIQNRLAAMEQT----STQGFQSVEIAHLYPSVLSTQEFLGWSEGPSWHYGIFPKLLHAA
PHCNSMDSEEQLKEFTGIQQWIVCDGAPNSTWIDSITCLLSDPPQLSLPNGQQIARPLST
FFLMEVAEASGMSPTVVGRCALVWCCGEQTWQCMLNVLMASLPHEYHLLQGTITELKKLA
EVLVPAVLRFLTRIGASSLLQVH-GHQTVCQGVAEVTSLARILRALLDPHLRLYEEEKT-
----EDFSGSDLATQ---SFRSSKS-----RVKPDSDNVNKRQRKHLLAISSFLFATVWG
FGGH--------------IPS-RH-WPLFDNFMRNSISSLSNYPEPPPSALVFDLRVNIE
DGTLVPFTGHYLSSCIRGSLGTFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2783)

SQTERLLYVVDLLLSNGQPVLLAGEIATGKSAFV
EVLVEPNHPSIHSPIHSALSSTHFRHLLSRGIPGQTQA-GTYLGHHQESKGSLLFLMEDL
HLAASDPDKICQPVLETLRQAMEGTIYARNTLELQTLQPTVNFLATATVPGYSERPLCPR
LFRLFTVLALDNMTQDTLLSRHVPGIQAWLERFPSVEREHTLARALVRASMEAWEAVCNC
FMPSPLHPHYRFSLHSVSHILG

ENSGT00910000144015_1_Linker_5_6 (2783, 3072)

SLQLLPTRTGSRGFVNTFHHQEHLRRVSGLRGTRLTIM
MSVRILVRLWLHEAQRTFCDRLDSDRERSHCANLLLQVAKSVFCCGPQSQPMVKDYEE-E
------VEEEKVPEVESEGEIAQWEDL-----SNSDSESEEEVDPYGIHASTGSFLGDSS
LAPFPI--K--SVNKENAESVSQ--MAEQEEDIRASRGELQSQTSEKSVWQRASQ-MDFS
LPL--LMPVLLLYPQENLSNLVFSLELTLGSNFENPN-FYLERQWENLEKQLAASAVRLK
LNPHLAQCRMM

PF12780 // ENSGT00910000144015_1_Domain_6 (3072, 3331)

TQHVARLVRVLARPRQHGLLLSVARGTGRHTAIRLASSICQARLFRLPS
-ESDQAISQCLRDASWYAGVLNQPVALLVPDNVNVALFHQLVALATSGSFPDQYTDADLD
KIEEHL-PKENYMVKLIMKKDTILHRFYQQVCSNLHM-FFLMRD--DQAPKQLPSTLFLR
LLQLATASVDRYEPWDQDSLVRIAQCHLENV-QSLPLDDGSLKCPDIKALIPNVAKIMAL
IHLSSACYHQHLCPALPLVTPKTFLDFLDM

ENSGT00910000144015_1_Linker_6_7 (3331, 3448)

FLLQQQQMILKMRMKA-CFNSALKTLRMMV
ERHSTQTNHLTDLEKQLKGSYKN------------VGVYQSQLEQSKLLFKLKMSECQHQ
ESLIENLIRQQDALQAQQEAFLEQMGK

PF12777 // ENSGT00910000144015_1_Domain_7 (3448, 3687)

AFLGPLNQLKVADFEEIRSYRAPPEAVVQVTNA
LCDLFHHETGWASAKQLLCTEDFYQELVFFPKEKLTDAELIKLNKALKAPGLSDKALRSV
SIPVANLAAWLWAVLHYGMAQRRGLPTGLLLRQVEAALAREQARLGQLQFQIDDLLEEIL
SLTKKLEEAQASHNLAMETLNQAQGGQFHKWPIRSLLLTPIHTWTEQLQKLKNHCKTVFG
DALLCSAAIVYLGPFPPQRRQELLEKWLSLCQGFE---EALEPDDVAQAMKQ--KSVRVT
-PKNPLVPTCSPFRILSLLSCGPEHHQWDRDKRPQAKSARLLGLLLRSHIHFNSCRWPLL
LDPSNQALIWLNPLPLKEDKNTLL-YLSIPAEHRV----TNQDSEEETEDEDDNGNDEED
RNETNNQNNGEEV-------------------KEQEEQETEKEKNET---ESSNSSTLSE
TP-SLPPCLTMLSGADPEL--GPQLLEAAANGLPVLLTNME--LSLGCQELHRLLSRENL
SPPHVQPGFCLYLSTTLPIHALER----VLGCELLKGLNVLDLGLNMDILEEQMLHEILC
RERPELETHWQDLQIRAVDISEAVTTAEERLLVTLLLQ--NQKRQKPSKFLRAMVRTQAK
ICQLNAQKEEIEEQKLEDMILWAPYRQIACHGMAIVEALSPLQNLLPFFCMKLENWMAAT
RQALDSMKPHDSYHGEDLASHLLQLKINLTRQLLTSTVAALGLTQAPLVGALGALALLQV
TKKTPKLERLAFWPGLSASPSIGHNTQVPGVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5028)

AWLGLRAWQECGMLELLPPFAGLRAS
LAGHSSVWQDYLSLSSTVLGPSPG--PNSEPLSLLQKLILWRVLRPDCLEGTLADLTTSL
LGRPLDENLSNPTMIFEQNWATQPILILLPPPGHPTAILHPLTVIRKLAANHEK--TQKH
LHVIALGSEDWDPVSTIVNTLCQAMLQGHWLVLDNCHLMS----HWPRELLQPLLRLLDG
ARVVSDSEL---LVEPESSNVATVHRDFRLWLIVSTEASSSLPGVLTWLSMPVFWDQSLE
LGRILIDSVG-SQQGLCMQP-LTQTLPLLLLHGLLLHRQLYGIKLQAHRGRWSQVTLTKV
LQIQKHLWASLSNPSAALLELAASVFYGASLKDPGDREALISLTGACLNPSNTSWVRY-T
PQYLLATLMPSPELGELDAMTECKARMHLLPTPAEPRACGLNEGPKSWRLRRQSRALLNM
LQQCSSTWVPSASGRN--AQHKERRLRQRLVQAKKRLVALQDLLTN-G--SCSGQSAIPW
AVLGPNARRPLEGFLETEVLELRQLVGILQRDLDCLLQQLKGKTPCTSSRCVAVAHALWA
GRLPRPWRSHAPAGPQLPWHWLRHLSRRGNLLIRYLDSGTSENANEPERIFHLSAFRHPR
RLLLALRWEAILES-----SEPCPNPTGTQGSGSG-----RVPPKRQELNNHPLHIRVEN
GPNPKVPKMGL-LLIGLQLQHAEWDKMDGALQDSFSSQPSPLPPVSVSTQARGASDARDS
GGLDVYSCPVYMTGPLGTTKLHSKNILMHLPLPTRLSPDTCIQRRVHVSSPTLS

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MQQGLQERVQN
CNRIRTGQGSIYLQRVQCQQLEKKLKQAEIWLLQLGKFARLVNYMICQSLVSILEDEITS
FVSNILQAPRQKPFLLSRLVFNDHSQLSHVPCGENMIRILTEGLQSVKASALQVVKSKDL
KTSRDSLPSEEEEEEEEEDSDTEFLVPKFQSQPSDAVRIFCGPNVGLVWPWKSHSIIDNL
VIRGCKLRGQYWPHNYKQLQEDLDNNAGIQQALTTQQVLLEGMLWEVQEFCKEHQWITDI
YEFLQPWGPQKLEEMIGCPIKNYVILVSRLNVWQAQVSKMPVELLTKGKLLLLSCHDVQA
ELKSKLESMRKDILTQVQNECCSRSQQLMTELTDFIRVFQIINSDVHAIAQCSQKLNEAN
EQYVSLEKRMEYIRSLHELIRIHFSLFTAENEALENS-----------------------
-------LLSVWETFQSEKSEASEFLLRNRHAIVPKLQKLIAAALAELESLLEKALSGPF
MDPTQEQRSTEHQLVSLERQFQNTVSHVSELHYAYATFTGDESPLPLPLCGTRP

PF08393 // ENSGT00910000144015_1_Domain_0 (1135, 1293)

IVQQQR
IWHLYRVISENISEWKCMAFAKFNLAMAREKTEGWLTEAARMSTTLGTHSPVLQRCMRML
EEFRSYLPLLTKLSSLQLQNVNYQSLFRALGLGSLQSMELLTLGQLLSCPLLEFADR--I
SQVWQCETERIHAQESLQRLQRYWEMRQLRLL

ENSGT00910000144015_1_Linker_0_1 (1293, 1326)

NFILHVPYEPPVLEHSKRQ---AVHSSQ
LEVVG

PF08393 // ENSGT00910000144015_1_Domain_1 (1326, 1602)

KDSGTFILSGYSSLEDSIQESLQTLLNILATQKSGDLHKVALEWVTIMHGLAYTG
ALLDVWVTFQQKWIFLNKVLYEMKIPFPSADLHSCFKALDDHYRTLMCISVADPMVLSLI
-VPSAKRSPHFQGQQLQQLLQAGSAELEGIIMALENVLYEVCAHFPRLFFLSDSELVALL
AAPLESHDTQLWVQRCFPHVHAVSFKSNSTD-EKNMGDQQA----SPGTQTQVEAFAVRG
VSGEEVKLQGPLPLHLDLPKWLASLEKCLRLALVHMLQDCVATRLARGPSLGKAFKK---
LHPKSQLS----QQLYVHHWLDLVEAFPWQCVLVAEEVVWCAEMEQALLEGGILVMVPEH
MHKLEVLVQFVRAQRASQDGQPLLSVRQTSLLSALLVKAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGPPHLFSKSPLQNLKTIAS-TESSLSPPACWIDVLGRSLLYNYEYLGPRL
EPLPILLPERPVLVLLLALEEVACGALVGPDGVGKTAMVNGLAWVLGRQLVMMPCLHQIE
ARCLSNYLNGALQGGAWLLLEAVQHLPPGLLSALGQRLDELHHLYAPLYQEVSRSIRTID
-------PTQPQLLGSGFFEKHQVSMRLGYGCLLTLRALGPAVPANLHLLLRPVSLSL-P
DLQRVAELTLLGAGMRDASRMATRLSKFFSLERELVSGSLPGRLPLLKQILEDTIQTLNV
SKVELNSQQPRSLAAIEEAALLHALLRSPLFNILDRVRLHNLQELLCGLFPSASHVLAEP
VTHRLMKPLMVEELRQVGLYPGPDILGSLDQLNQALSRSSGILLLGLAGSGKTTCWQSLF
KIQNRQIATQGT----STQGCQQVEITHLYPSALSSQEFLGWLEGPCWHHGVFPRLLRAA
PQYNSMGSKGKTEESKGIQHWIVCDGASSAAWLDSITCLLSDPAQLSLPNGQQMARPPGT
FFLMEVADATGMSPTLVGRCALVWCGGEQTWQSMLSILMAALPHEYRLQLKTVTELNRLA
EVLVPATFRFLTRQGASSLLQVH-EQQAVCPGVAEVTSLARILRGLLDPHLRQDKEEKAR
--GSEDLIYSDPVVQ---RVSSSKSSSQ-NKSQVDSDGEPNKRREHLRAVSSFLFALIWG
FGAH--------------LPS-RL-WPLFDTFMRSSINCLSNYPDLPPSVLVFDLHVSPE
DGTLVPFTGQYLSSRIKGILGTFHPSTQTERLLYVVDLLLSRGQPVMLAGEAATGKSTFV
EVLVEPNNPYTYSSIHPAFGSTHLRLLLSRGFQGQTQA-SPRPGQHQDSKGSLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHNTLELQTLQPVVNFLATATVPGCCERPLCPR
LCRLFTVLALGSMTQATLLSRHTPSIQTWLERFPSIEQEGVLARALVRASVEAWEAMCNY
FMPSPLHPHYRFSLHSVSHLLSSLQLLPTRMGSRSCMDCLNHQEHLRRVSGLRGTRLTVM
MAMRNMVRLWLHEAQRTFCDRLNTPRERSYCADLLLEIAQNVFCCGVGPQHLGKDYEEDE
-------EREKVPEVESDGELAQWEDL-----SSSGSETEEEEDPYGLHVTTASHMSDPC
PAPST---R--PGSRETTESTSH--QIGQEEATKASSYKIQAKK-CKNVWQKAPQ-MDLV
SPL--LLPVLLLRPQEKPSDLVFSQKLVLGSYSDSPN-LYLERQWETLEEQLATSATQLR
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLATSICQVRLFHLPY
-GSEEAVLQCLRDASWHAGVLNQPTALLVPKGVDLITFHRLLALATSGSFPDQYTESDLD
SIEEQL-PRENTGVKQSMKKECLLQRFYQQVCSHLHM-FFLIGD--DQAHKQLPSTLFLR
LLQLTTTSIDHYEPWDQAALVKVAKYHLAGA-QNLSHDDSSLKYPDLQASIPSVAKAMAF
IHLSAASYHEHLCPVLPLVTPKTFLDFLNTFLLLHQQFTLKMKNRAQRIQNALENLRMLI
EQHSTFTSLVFNLEQQLKGSHKN------------VSTFQQQLEQSKLLYKQQLLECRHQ
ENLIENLIKQRDALRAQHEAFLEQMGKAFLGPLSQLQVTDFEEIRSYRSPPESVVRVTDA
LCDLFHRDTGWASAKQLLCTEDFYQELVFFPKEKMTDSELIKLNQALKAPGMSEAALRAV
SIPAANLAVWLWALMRYGLAQRRGLPTGLLLRQVEATLTREQARLGYYQFQAQEMLEHTM
SLTKKLEEAQASHSQVIETLNQAQYGQYHKWPIEAALLTPMHTWITQLQKLKVRCMTMFG
DVLLCSAAIVYLGPFPPLRRQELLDKWLALCRGYQ---EALCPDDVAQALKQGQKSISRP
-PKNPLLPISVPFSILALLSSESEQYQWDQDLKPQAKSARLAGLLLRSLTHYDSCRWPLL
LDPSNQALIWLNPLPLEEIRRVAQTPTEGRGEGKG----MFGSQKEGLRIFL------HT
CSFEMKSSPEAVPPLRRAPLHLCGPGS--------DLMRNHSRENGEEEAESQGPKLASE
TPS-PPLYLSVLSGADPGL--GPQLCEAAASGLPVLLTNME--LGLGCQELQWLLQRDQL
SPPEVQPGFCLYLSTTLPLHTLEK----VLGCELLKGMNVLDLGLNMEILEEQMLHEILC
RERPELENRWQDLKLRALNAHKAVEAAEEHLLLMLLHQ--DPKHQKPAKFLRDMVRAQAE
LCQLRAHCEEVEEQKIQEVVLWVPYRHVAWHGMAIVKALSPLQNLLPLFRVSPENWLAAT
KKALDNMKPHDNLHGEDLDSHLLQLKIHLTHQLLGSTVTALGLTQVPLVGALGGLALLQV
TSKATKLERLAFWPGLAASPSTSHRKPASGV

PF03028 // ENSGT00910000144015_1_Domain_9 (4232, 4993)

TRPAWLGPKAWQECGVLELLPPFVGLCAS
LAGHPNMWQDYLSLSSTVLGPAPG--PGSEPLSLLQKLILWRVLRPESLAGALKDFTTSL
LGRPLDEHLCTPTVSLERSRATQPILILLPPPGQPRATLHPLTVIEKLASKHEQ--GQKH
LKVIALGSEAWDPVPVVISTLCQAVHEGHWLVLDNCHLMP----HWPKELLQPLLQLLDE
AKVVSDMES----ARSENGNVATVHRDFRLWLIVSAEASASLPAVLAYHSMPVFWDQSLE
LGHVLVDSMELAQQGLYMQP-PYQALPLLFLHGLLLHRQLYGMRLQGHRGRWSQVTLTQV
LQTQDRLWATLSNPNAAMQELAASVFYGGALGDTEDREALVSLTQACLSPSSRSWAQPHT
PQYLLATLMPSPDLEELDAIAECKAQMHLLPTPPEPRICGLTEGPQASLMRRQSRVLLSA
LQRSSPTWVPAAPAGA---RRTERRLRQRIVQARRRLDSLQALLTEAPRHDES---GASW
DVLGPNVQRPLERFLETEALELGQLVNRLQRDLDCLLQQLKGAPPCPSQRCAAVAHALWN
GRLPAPWRSHAPAGLQPPWHWLRQLSRRGQLLVRYRGLGVDTGAEVPERVFHLSAFRHPR
RLLLALRWEAALDR-----CVPSWSCPDSQSLGAS-----TLRQKRRELNSNALCLRVEN
DPNPTVPEMGL-LLIGLQLQHAEWDPIAGALQDSSCSQPSPLPPISVSAQPPGGNDLPLQ
AGLAVYSCPVYMAGPLGTTKLHSGNILMHLPLRTKLSPAICIQRRVHACSPPLP

------------------------------------------------------------
--------------------------------------------------------MVPE
EKRVGLSSDETSSDALKSW-HSICVL-DSKEEPLACQQKQRQFVKPATESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDFLPFLEQLYCWAPWVQTHL
HLDLLGAINQAFPPDSSLLDSASHADCCPQKQRLHHRPPCPACPFVQARWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRKETRSQLDYEVPREKTLQKSSTGFSPETSFLGSQVMTTLKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQEALAKEKHKALRLLHHCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRAGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILEEQITS
FVANILQAPRQKPFLSSQLVFDDHDQLSHVPCVENMIQILTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKTEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVRGYRLRGQYFPRNYKQLEEDLNNNPQIQQALNIQQVLLEGVLWEVQEFCREHHWITGI
YEFLQSWVPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPIELLTKGKLLLLSCRDVQT
EMESKLDSIRKDILAQVQNECWSLSQKLMTELTDFMHVFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELICNHFSLFSAENEALDISVRRQFGESPILPRPPPPRPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIIPKLQQLMAAALAELEGLLGKALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTHPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTESWLTEAARMSTTLGLNSPVLQHCMRIL
GEFRSYLPLLAKLGSLQPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIRQLQRYWEVRQLRLLNFILHVPYEPPASEHSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIQKSGDLNKIALEWMAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AAQLESCEAQLWVRRCFPHVHGVRFKSCPTG-EKNMDDWES----SPNAQTQVEALAVLG
AGGEEVKLQGPLPLHADLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVTARLARGPSLGEALKQ---
LPKQNKLY----LQLSVQHWIDLVQTFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSVH
MRKLEVLVNFMRAQRASQGGQSLPSVRHTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTAS-SEHSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPNGVGKRAIVSSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHRLYAPLYQEASRNTSTID
-------PTQSQLLGSGFFEKHHVSMRLGYGCLLILRALSSAVPANLHLLLRPVALAL-P
DLQQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIQTLNV
TKEEPKCQQPRSLAAIEEAALLHALLRSPLFSVLNGLHLHNLRGLLCALFPSASQVLAEA
MSYKLMRALVVEELQQVGLHPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
SQCNNMGQKRQTEESMGIQHWIICDGASSSAWLDSITCLLSELPQLSLPNGQQIARPPGT
FLLMEVADATGMSPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNRMA
EVLVPATFRFLARQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDPHLRLKEEKAP-
--GPEDLSCSDPVAQ---SFRSSKSSFL-NRSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2783)

QTERLLYVVDLLLSRGQPVLLAGEAATGKSVFV
EVLVEPHHPYIYSPIHPALSSTHLRLLLSRGIQGQTQA-SPQPGHHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVEREHALARALVRASVEAWEAMCNC
FMPSPLHPHYHFSLHSVSHLLSNLQLLPNRTGSRSFVDYPNHQEHLRRVSGLRGTRLTIM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQNLGKDHEEEE
E---EEEEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVATSSNSSDPS
LTPSI---G--PVSRGMRESISH--KIRQEKGTRASNYRLQVRRSFKTRWQKAPQ-MDLV
SPL--LLPVLLLHPQEKPSDVVFSQELTLGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSSHLAQCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPS
-GSEEAVLQCLRDASWHAGLLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
RIEEHF-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-QSLPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLI
KEHDTHANLISDLEQQLKASSKS------------LSMFQQQLEQSKLLYKQQLEEC

PF12777 // ENSGT00910000144015_1_Domain_7 (3418, 3687)

RHQ
ENLIENLAKQRDALQVQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMSDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLIREQARLGYYQFQAQETLENNL
ALAKMVEDAQASHNCVAKTLNQAQCGEYHKWPMKAALLMPMHAWTIQLQKLKGRCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKNPLLATHSPFSILSLLSSASEQYQWDRNLKPQAKSAHLAGFLLRSPTHYSSRRWPLL
LDPSNQAIIWLDPLPLAENRCLAPAPTEGRGKGLM----RNQNTESK-MDMKEEDDDSKE
TNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESIWPKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RECPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNMVRAQGK
LCQLRAHCEELEGQKLQEMVSWAPYRPVVWHGIAMVKALSQLQNLLPLFRMSPEKWLAVT
KQALDSMKPREINHGENLASYLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVSGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECETLELLPPFVGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMGAPTMPFKHSRATQPMLILLPLPGHPTATLHPLTVIQNLAAKYQQ--GQKH
LQVIALGSEVWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLGQPESRNVATVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPHAAMQELAASVFYGGPLGDTEDREVLFSLTQACLSPSSRNCVQPHT
PQSLLAMLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRVLLSA
LQRSSPVWVPETRGGA---QLAERRLRQRLVQVIRRLESLQDLLTNLVRQDES---GAPR
SVLGPNARRPLEGVLETEALELSRLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADANSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGAVSS-----PLPYKCLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPPP
ADLTVYSCPVYMGGPLGNTKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

------------------------------------------------------------
---MKPHSQTS-PPSLPMPSTSCRPGQTQKPKAWNWHLDPELWARSVRQQLNTCLHFILE
EKK------NPWFYTLQSG-LVGCSC-SGQEHSWDCQMKQ-EDLKAVVESEQRTLLKLLL
SELQSLFSAVMQDGSCEAWRYLHAVLGLLPPYREMLAGQLELLPFLEQLYCWAPKVQARL
ELDLLDAIDKAFPPDSSLLHSSSHVDCGLWMKRFHRGPPCSACPFVKAQWDRQQK-KELA
TWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLPLALATDIPVQYESSDTEQAEGEP
AGR---KLQVASEAPEEKALKKKS----SRTPVLRSQVKSLLERDWTQKKIHFLYLNVVS
DRHFNPYKLVAVPPDKVNPEHYIFSPFGILHIHPVEGSEAMTLGTWHRDCALWRELQRIP
FFKNCLLRKALTCWKKNVRLCGLHRIQTFLKTHLLSAIPHFGAGMLHINRLLQEFRSVSW
LPKEPDRSYELVDLQKAIAKENHKALRVLCHFLNLCTSILQLIHEDTYQMQQGLQERVQN
WNRIRKGQGSIYLQRTLCRHLEKKLKQAETWLLKLGKFARLIDYMICQNLVSILEDEISS
FIANTLQAPRQNPFLLSQLVFDDNGQLSPMPRVESIIQGLIKSLQSIKTSALKVLQSTDL
RTSRDLLYSE---DNKDQDSNAEFLMPKFHGKASDAVRLFCGPNVGYVWPWKSHAITDVL
EVRGHKLRGQFLHPNYDHVQEDLDKNAGIQQALAVQQSLLEDMRQEVQEFCNKHKWVEGI
YEFLKAWSSQKLEDLRGSPINNYVNLVIQLKKWQERVSNMSVELLTKGKLLFLSGHDVQE
ELGSKLNNMRKNILEQAQNECWSRNQQLMTELTEFLRVFQTISSDIHAIAQCSQKLSEAN
EQYCQLEERVEYVRSLHDLIRNHCALFIAENETLDIA-----------------------
-------LLDLWEAFQFERSQVSEFLLSKQHAIVPRLQQLMAAALAELEGLLAKALSGPF
MDPSQEQRSTEQQLGALEHQFLNILNNFNALCNAYCTFTGYKKPMSPPASGNRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

LQQR
IWRLYRIISENLGEWKCVAFSKFNLSMAREKTDAWLTEAVRLSTALGLQSPVLQRCMRML
EEFRAYLPLLIKLGNLQLQDLNTQSLLRALGLGSLRSLDLLTLGQMLNYPLLEFAER--I
NQVWQYDKERIHAQEILQQMQQYWEGRQLRLLNFILHVPYKPPTSERSKRP---ALRSPQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGQLHKIALEWVAIMYGLG---
ALLEVWVAFQQKWIFLNKVLHEMKIEFPAPELNARFKAMDDQYRTLMRISVADPMVLSLI
-LPNTKRSPYFQGQHLQQMLKAGSGELEAIIMALEDVLYGVCANFPRLFFLSDSELVALL
AAPLDTREAQLWAQRCFPHIKAVNFRSKSTK-KKI--N-QD----SSSSTESAETIAVLA
AGGEEVKLQEPLPLHTDLPKWLASLEKCLRFIIVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLIKALKA---
MPQQRQMP----MQVYVQHWLDAVQVFPWQCILVAEEVVWRAEMEEALLESRTMHMRSVH
VHNLEVLVQFIRSQRSSQDGKSLPSVRQTSLFSTLLVKAVTHRDIAQLLEKNQVSDLTDF
HWVRQLKYHLGSSHLNLKSPVQCLTTIAS-TEPSVSPAACWIDVLGRSFM

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYMGPKL
GPLPSLMHERQVFILLMALDEVAYGAILGRDGLGKAETVNSLAWTLGRQLVIMPCLPQIE
FQCLRNYLNGALQSGAWLLLENVNQLPSSLLSALGQRLDELHYLYAPLYQKASKNISTIN
-------PTKPLLLGGGFFEKHQVSMRLGFGCFLTLHSLGPDIPANLHLLLRPVALAL-P
DLQRVAELNLLGAGVQDASQMASRLSKLFSLERELVSGNLPCRLPLLKQVLEHTIQTLNT
SQ-EKKSQQPYDPAASEEAALLRALLHSPLFSILDGLRLQKLQELLCGIFPNASHVLAEP
VSHRLIKSVVVEELQQLGLFPASNTVTSLEQLSQALSRASGILLLGPAGSGKSTCWRSLF
KIQNRLAAMEHT----STKGFQSVEIVHLYPSVLNSKEYLGWSEGPSWHYGIFPKLLHAA
PYCKSVGSEEPSEKFTGIQQWIICDGAPNHAWTDSVTCLLRDPPQLSLPNGQQIARPLGT
FFLIEVAEAAGMSPTVLGRCALVWCSGEQTWHSMLSVLMASLPHEYHLQQETITEFNYLA
EVLVPSVLRFLTRIGASSQLQVH-GHQAVCPGVAEVTSLVRILRALLDPLLHLFEEEKSY
--TKEDFSGSDLVTQ---NFKSSKT-----RVQSDRVNVNKKQRRHLLAISSFLFAIIWS
FGAH--------------LPS-RH-WPLFDDFMKKSISSLPNYPEPPPSALVFDLHVNFE
DGTLVPFTGQYLSTHVKGNLGSFQPS

PF12775 // ENSGT00910000144015_1_Domain_5 (2547, 2783)

SQTEQLLYVVDLLLSNGQPVLLAGEIATGKSAFV
EVLVKPNYPVIHSPIHPALNSTHLRHLLSRGVHGQTQA-SSIPGHHQDSKGSILFLMEDL
HLATFDPEKNCQPVLETLRQAMEGTIYAHNTLELQTLQTTVNFLATATVPGYSERPLCPR
LYRLFTVLALNSMTQDTLLSRHVPSIQAWLERFPSVEREHTLARALVRASVEAWEAVCKC
FMPSPLRPHYRFSPHSVSHILGSLQLLPTRMGSRGFAETFHHQEYLRRVSGLRGTRLTIM
MSMRVMVRLWLHEAQRTFCDRLDSDRERSHCAKLLLEVAQNVFCGGPGSESLAKDCEEEE
------VEEEKVPEVESEEEIAQWETL-----SNSDSGSEEEEDPYGLQATTGSFLSENS
LAPFPR--K--SVNKENTENVSQ--MAEQEEDIRDSSSKLQSKT-PKHEWQMAPQ-MDLS
LPL--LLPVLLFYPQESPSDLVFSLELTLGSNFESPN-LYLERQWENLEKQLVATAVRLK
MNSGFSQCPVMVQHVAHLVRVLARPQQHALLLSEFRGTGRYTAIILASSICQAHLHYLSV
-ESEEAIFQCLRDASWHAGLLNQPVALLVPEGVNVAIFCRLLALATSGSFPDQYTEADLD
NIEEHF-PKENIANKHAIKRDTILNRFYQQVCNNLHM-FFMVGD--NQAQNQLAPTLFLN
LLQLTIASVERYEPWDQASLVRIAQFCLEND-HSLPLDDGSLKYPDFKHLIPNVANIMAR
IHVSSACYHKHMCPALPLVTPKTFQDFLDMFLQQQQQMVLQMRMRASRIQTALKTLRLMV
ERHSTQTSLLTDLEAQLKGSYKS------------VGICQGQLEQSKIMYRQKMIECQHQ
ESLIENLVRQHDALKAQQEVFLEQMGKAFVGP

PF12777 // ENSGT00910000144015_1_Domain_7 (3453, 3687)

LSQLRVADFEEIRSYRAPPESVVKVTDA
LCDLFHQETGWSSAKQLLCTEDFYQELVFFPKEKLTDSELVKLNEALRAPGMSDAALRSV
SIPAANLAVWLWAVLRYGLAQRRGLPTGLLLRQVDATLAREQARLGQFQFQAHDLLEQTR
SLTKKLEDAQVSHNHVMETLNQAQCGNFQKWPMESALLTPMHMWTTQLQKLQEQAKTVFG
DALLCSAAIIYLGPFPPQRRQELLEKWLSLCQGSE---EALDPDDVARALRQ--KSVGV-
-PKNPLLPTRTPFSILTLLSYGSELHQWDRDLKPQAKSARLLGLLLRSHIHFSSSRWPLL
IDPSNQAIMWLNPLPPKQNRSLEPSPKESKEKFHV----TKQDSGDNTEDELEDENN-EE
EDEANEQRKEQKAEENKI--QG---------ENEQEVQETEKENEPESSG--SHSSLPSE
TQ-SLPSCLTVLSGTDPEL--GPQLLEAAANGLPVLLTNVE--LSLGCQELQWLLSKKNL
SPPSVQPGFCLFLSTTFPIHALSR----VLGFEMLKGLNVLDLGLNMEILEEQMLHEILC
RERPELETRWQDLKIRAADTYEAMKADEEQLLVTLLRQ--NQKRQKPSKFLRKMVRTQAK
ICQLNAQMEELEDQKQEVVALWAPYRPVAYHGMAMVEALSPLQNLLPSFCMTSENWLAVI
RRAIDSMKSYDSYRGEDLPSHLLRLKIHLARQLLTNTVVALGLIQTPLVGAFGALAMLQV
TTKTPKLERLALWPGLSASPSSGHNMQIPGVIRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLSSKAWEECGALELLPPFAGLCES
LAGHSGVWQDYLSLSSTVLGPAPG--PNSEPLSLFQKLILWRVLRPDCLAGALADLTTSL
LGRPLDENLGAPTMIFEHIQPTQPILILLPPPGHPTATLHPVTVIRKLAANHEK-VPQ-H
LHVIALGSEDWDPVSTVVNTLCQAMLQGHWLVLDNCHLMP----FWPRELLQPLQGLLDR
ARVVSDSEL---LAEPESRSVVTVHRDFRLWLIVPTEASTSLPGMLTQSSMPVFWNQSLE
LGRILIDSLD-SQQGLCTQP-LTQTLPLFFLHGLLLHRQLYGLKLQAHRGRWSQVTLTRA
LQIQEQLWASLGNPSAALLELTASVLYGGSLGDLEDREALVSLTRTCLNPRNMNWDQPHT
PQYLLATLMPSPELGELDARTDCKAQMHLLPTPPEPRTCGLNEAPQAWLMRRQSRVLLNA
LQKCSSTWVPTVCGGI--AQRKERQLQQRLAQAKKRLVALQALLTNNR--IRSGQCVTPW
AVLGPNARRPLEGFLETEVLELKHLVGTLLCDLDCLLQQLKGGTPCTSSRCAKVAQALWA
GHLPQPWRSHALAGSQLPWLWLRQLSRRGHLLIRYLDSGMSENANKPERIFHLSAFRHPG
RLLLALRWEAVLEN-----SVHNPNLPGHQDSISG-----SLPPKWQELSNHPLHIWVEN
GPNPKVPKMGL-LLTGLQLQHAEWDQTDGALQDSFSSQPCPLPPVSISTQARRGKDAPVS
AGLGMYSCPVYMTGPFGTTKLHSKNILMHLPLPTRLSPDTCIQRRVHVCSPTLT

------------------------------------------------------------
--------------------------------------------------------MVPE
DRRVGLSSDETSSDPLKSW-HSICVL-DSKEQPLVSQQKQRQFLKPANESEQPTVLELLV
AELRTLFSAVLQDSSPAAWCYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAIVQAFPPDNSLLDSASHADCYPQKRRLRHRPPCPACPFVHAQWSRQQVKEELA
TWLRPLTLPELQCCLGIIGAEVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
AGRKETRSQLDYEVPREEAFQKRSTGFSPETSFQNTQVMTVLNMERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNPEHYVFSPFGILHIHPVEGSETMTLGTWHHHCVLWQQLQLIP
FFKYCLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELCSASW
LPQELDRCYELQDLQKALAKEKHKAVRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRTGQGSIYLQSVQRKQLEQKLKQVEAWWLQLGKFARLVDYMICQSLISILEEEITS
FVANMLQAPRQKPFLSSHLVFDDHGQLSHVPCVENMIQILTGGLQSVKASALQVMQSADL
KTSLDSLYSE--EEDEEENPKTEFLMPKFHGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVRGYRLQGQYLPPNYKHLEEDLDNNPQIQQALNIQRVLLEGMLQEVQEFCREHHWITGI
YEFLQSWGPQKLEDMRGCPIKNYVMLVSRLNVWQARVSNMPVELLTKGKLLLLSCHDVQA
EMESKLNSIREDILAQVQNECWSRSQQLMTELTDFMHVFQTINSDIHAIAQCTQKLNDAN
EKYIELEERMEYIRALHELIRNHFSLFSAENEALDISP----------------------
--------HLFHCPLLFEKSQASEFLLNKQHSIMPKLQQLMTAALAELEALLGKALSGPF
MDPTQDQRSTEHQLISLERQFENTVSDLSELHHAYAIFTGDETPLPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFGKFSLAMAQEKTEGWLTEAARMSSTLGLHSPVLQHCMRML
GEFRSCLPLLAKLGSLHSQSLNCQGLLRALGLGSHQTIELLTLGKLLTYPLLEFADR--I
NQVWQSENERIHAQETIRWLQQYWEARQLRLLNFILHVPYEPPASERSKRQ---MLRSPQ
WEVVSKDSGTFILSDYNNLKDSIQESLQVLLKILAIQKSGDLNKIALEWVAIMHDLG---
ALLEVWVTFQQKWIFLNKVLHEMKIQFPSADLSSRFKAMDDQYRTLMCISVADPMVLSLV
-VPNAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQRWVRRCFPHVHALSFKSHPTG-EKNRDDWES----SPNTQTQVEALAVLG
VGGEEVKLQSPLPLYPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAAHLTQGPSLAEALKQ---
LPKQNQLY----LQLHVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFLRAQRASQGKQPLPSVRQTSLLSALLVMAVTHRDIAQLLEQHKVSDLTDF
HWVRQLKYHLGSPHIIPKSPIQSLKMTAS-AEPSQSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPKGVGKRAIVNSLAQALGRQLVILPCSPQIE
TQCLSNYLNGALQGGAWLLLEAVHQLPPGLLSALGQRLAELHHLYAPLYQEASRNTSTID
-------PTQPPLLGSGFFEKHHVSMCLGYGCLLELRALSSAVPANLRLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFRMATRLSKFFSLERELVSGPLPCRLPLLKQILKDTIQTLNV
TKEEPESHQPRSLAAIEEAALLHALLRSPLFSILNGLHLHNLRGLLCMLFPSASLVLAEP
MTHKLMKPLVVEELQQVGLHPSPDILGSLEQLSQALSQASGILLLGPAGSGKTTCWHSLF
KIQNRLAAVEET----STQGCQPVEITHLYPSGLNPQEFLGWLEGTCWHHGIFPKVLRAA
TQCKNMGQKRQTDKSMAIQHWIICDGASSAAWLDSITCLLSERPQLSLPNGQQIERPPST
FLLMEVTDATGMSPTVVGCCALVWCGGEQTWQCILSALMASLPSEYRLQHQTVTELNHLA
EVLVPATFRFLTGQGVSSLLQVH-GQQAVCPGVAEVTSMARILHSLLDLHLHLE-EKAP-
--GTEDLSCSDPVAQ---SFRSSKRIFL-NQSQDDSDDVPNKSREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSIQ

PF12775 // ENSGT00910000144015_1_Domain_5 (2549, 2784)

SERLLYVVDLLLSGGRPVLLAGEAATGKSAFV
EVLVEPYHPYIYSPIHPAFSSTHLRLLLSRGIQGQNQA-SPQPGQHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLSRHVPIIQAWLERFPSVERESALARALVRASVEAWDAVCNC
FMPSPLHPHYHFSLHSVSHLLNS

ENSGT00910000144015_1_Linker_5_6 (2784, 3071)

LQLLPNRIGSRGFVDYPNLQEHLRRVTGLRGTRLTAM
MATRNMVRLWLHEAQRTFCDRLDSPRERSYCAKLLLIVAQSVFCCRPGPQHLGKDHEEGE
E---DDEEEEEVPEVESEGELAQWEDF-----SNSNSETEEEEDPYGLQVPRGSNSSDPS
LSSST---G--PVSRGMMESISH--KIRQEKGTRASNFKVQVKRSFKTWWQKAPE-MDLV
SPL--LLPVLLLYPQEKPSDLVFSQELILGSNPETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHS

PF12780 // ENSGT00910000144015_1_Domain_6 (3071, 3328)

MAQHVARLVRVLARPRQHGLMLSGALGTGRHTAITLASSICQAHFFQLPS
-GSEEAILQCLRDASWHAGMLSQTVALLIPSGVDLTTLHCLLALATSGSFPDQYTEADLD
HIEDHL-PRENLGIKHNIEKEMVLQRFYQQVCSHLHL-FFLIGD--KQAHQQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-QSLPLDDSSWKYPDLQPSIPSVAKAMAL
IHLSATFYHEHLCPALPLVTPKTFLDF

ENSGT00910000144015_1_Linker_6_7 (3328, 3425)

LDTFLMLQQQMILKIKNKAQRVQNALGNLRMLI
MEHSTHANLIFDLEQQLTSSFKS------------LSVFQQQLEKSKLLYKQQLEECRHQ
EQLI

PF12777 // ENSGT00910000144015_1_Domain_7 (3425, 3687)

KNLAKQRDALQAQQAAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVQVTNA
LCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKMTDSELIKLHLTLMAPGMSDAALRAV
SLPAASLAAWLWAVLHYGLAHCRGLPTGLLLQRVEATLTREQARLGYYQFQAQETLEHNL
ALAKMVEDAQDSHNCVAKTLSQAQYGQHYKWPMEAALRSPIHTWTTQLQKLKGHCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCGGFQ---EALGPDDVAQALKQKQKSVSMP
-PKNPLLATHSPFSILSLLSSESEQHQWDQNLKPEAKSARLAGLLLRSPTHYRSCRWPLL
LDPSNQALIWLDPLPQEENRCLAPAPAEDRGKGLM----RNQNRESK-TDMKEKADDSEE
SNEAKDQTKEQEAEERKNEQE---------K------EPEDKEEKEEEKTESQGSKPASA
TQLPSLPYLSVLSGADPEL--GSQLQEAAARGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCALEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RECPELETHWQDLKIRALDACKAVETAEEQLLLMLLFQ--KPKLQKPAKFLRNMLRAQAK
LCQLRAHYEEIEGQKLQEMLLWAPYRPVVWHGMAMVKALSQLQNLLPLFRMSLENWLAAA
KQALDSMKPREINHGEDLASHLLQLRAHLTRHLLASTVTALSRTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVPGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPRAWCECEMLELLPPFAGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLADALADFTTSL
LGRPLNENMGAPTMPFKHSQATQPILILLPPPGHPTATLHPLTAIQKLAAKHQQ--GQKH
LQVIALGSETWDPVSVVVSTLCQAMCEGNWLVLDNCHLMP----YWPKELLQLLLELLGR
ARVIADLKSQQLLGQPESRNVATVHRDFRLWLIVPAEASASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYTQP-LTQALPLLLLHGLLLHRQLYGVRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPTVAMQELAASVFYGGPLGDTEDREALLSLTQACLSPSNRSGVQPHT
PQSLLATLMPLPELRELDAMAECKAQMHLLRSPLEPRLCGLNEGPKAWLLRRQSRALLSE
LQRSSPMWVPASPGGA---QLVERRLRQRLVQASRRLESLQDLLTHGVSQNES---GAQW
SVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVANALWT
GRLPSPWRPHAPAGSQPPWHWLRQLSRRGQLLVRYLGVGADAGSDVPERVFHLSAFRHPR
RLLLALRGEAVLDQ-----NVPSSNFAGSRGSFSS-----QLPYKRLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPTTGALQDSPSSQPNPLPPVSISTQAPDTSDRPPP
AGLTVYSCPVYMAGPLGTTRLQSRNIVMHLPLPTKLSPSTCVQRRVHVCSPPLP

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PF08393 // ENSGT00910000144015_1_Domain_1 (1131, 1605)

GQQRLEAREA
VWRLWSSSAEQVRAWKQKQLLQVDAESVKEKIQGWGRRLQDLGSLFSGEDPLIRRVQDHI
EEFAALLPLLVRLSSPALKPKHWETISAVMGT-KLPGPEELTLSDLLTYPFLLHQEL--I
QKVIGSAQKERSSAQTLRRVRSVWEQREFQLNRFFLCVRTQDPSPDPSQRPPSGRFQEAE
EGLTTKDSGTFLLKDVGSLYRELGDSLLSLHMVNASYLSSDMKKEVSDWTQKLQSLG---
RSLDLWISFQEKFVFLTRIQQELHLPLPSHQATEEYQSVERSYRALLGATVRDPRVLSVL
SRPSSSQEGEFHGEALCDALHRGISAMEKIVEGLEGVLDSFRSVCPRLFFLSDPDLLRVL
TASAEPEERLPCALLCFPKLTNVLFQEQPPKPTD-----------FPLYSSRALTVGVVG
SYKETLSLNSPISGNLEATTWLSELERGLKGALFSQLDKCLCYQRAVGDQAVT-------
------------YSGGAQTWAARVTAFPWQCLAVSEEILWCEAIETFLFTPHRASLKNKA
QQKVTTLARVLPELHAVGGVSKAGVHLAQAVLSAWITLACLQRDRTCALVDEGVQSCDSF
AWVKMFKYRTQA------EPVQTLETRRSQ-----MTPSVYAEVLGSQLPYCYEYVGLDT
GIVGCPLSDRVTLGLILALQQYQCGAVIGQDNDSRTQTLVALGSALGCQVVVLKCWAETK
LGRVSQHLRGALQGGAWLVLDSVHQLSAKVQSSLGQLLREIQSSCQALLPKDRTRDSVQG
VSSPNDVCYLPQEIGSIQLEGRAITVRESYGCFMTLPDSTSTLASNLSLLLRPVSLVA-P
DLHPTAEIMLMAAGFLQPSHLASKVSCFFRLARESGALTGNSCFSLMRSVLRRAELLLKR
RN-MSRCAEGQDMD-LEQEKLLLRVLSSALLLEHPFDRHNHLMDLLKGVFPMCSSPLLCP
EPWASLQSTIDQEVNELGLRVHSEFCGKVIQLFHAIQQSP

PF07728 // ENSGT00910000144015_1_Domain_4 (2141, 2308)

GVLLTGPPGSGKTSCWRVLS
RVINRLAGSADMQGVPSEYTYNALQPTHLFPSSYSAQELFGGLEEAKWKEGIIPPILQRA
T------------QGFGASKWLVLDGPAAPKWLEPVSCLFGHHPVLTLANGQHLCLQDPT
KVIFEMTDASAITPALLASCSMVYVGGRDTWRAVLASFMSTLYVRYQIKESTALHLQSLS
ESLSAQLLSFLEEHCTPALYPHCTQSVHTAQGVQEVSSFCAILQSLMDQHLLRHCGPEAS
--SETELQNTGP--QV---VASQKTHE---KLDNLPTDQANTPHHHRMVHTYFLYSIIWG
FGGH--------------LHP--KQHTKFDAFLREKLQDLLLSTDIPSGTSLFDILPGPD
GGSFRSSHEM---CPRGLSLGGFVALPQFESPRFVVRSLMSSGQSVLLVGEPGSGKTTFA
QSVIPRNITSLCIPVNPMLHPDWLRNLIIGHQEDPHNL-NPPRDKTKSQRFQHLFFMDDL
HEASRDPDCQTPAALEALRDVATSV-----GSKCADATPWHSFLGTINSPDHGYDCLNPR
LSRLFITIALPLCTPGSLQSILAPRFSNWLKLALPASQLRELGTALARATETLHHEV---
--RRSLPVGYHFSLHHVHRLQQSMILLCPSLAAQ--------------LALPKGTAPTDL
LGTQAVSRLWMHEALRTYSDGLPTQRDKESFCNLLINCTLRAFCPAPTSPHRNRSSGART
L---------SPPNSKLGGPLSASPGTRRGTSCASGTQSGKGQPPAGHGE-----SVPPA
VAPGIEGGASPSVSTSGAHSVQEREPKGQESAVEDANASLAPST-PDNSYPSTPSSTRSI
SPTTRNPTPNFLRTVEDLETLVFCHDLSPGCPERGECPPYRERA-----AQCPDSENPL-
---KLILSPSDQLHVAHLSRLLRLPQGHVVLLSQSPGTGRRSLAKLAASTSNCQLLELSA
SQSQEERHGLLRGASWRAGVLGGAVALLVPEEVSQNSLQEVAALLRDGTFQGLHSAEQEE
KALQALQQRERL----HHRGHQVLRDSYINRSGNVSRCLFLTHSPTDVGAHSFPLGIPVP
RR---QQKIVLYKIYIWSPIIKMSECAYTGTHGGH--KHSHSHSLGLLQAEVSLSRLMSL
IHVTARCHYDRLCPTLPLITPKTFIDFIHIYLRFAADLRGRRGQERDRLEAAVCRAQEVQ
EEREEREEELRVLNDQLHESRRTLSLSP----------AELSLQKEVKDWRQQLKEARDS
HELLQVQHQELERSRQCLESKLHPMKNQWLRAQRQLQLSDLEEIRSYRHPPPLVVMVTNA
LCAALGKEQTWEAAKQLLASENFYQELQFYDALTMGDAPFATLTRAVTQPHFRPETVSLA
SSAAASLCGWLCSLQHHCAVLRKLHSTKATLTQVEAQDWRLASRMAEIRLQQEKQRQLEA
QASHHLQEVTGSRRALRGQIVQSQGRLKAAMECERRAAPHFSCWTQALEVQRGRAQTVPV
DALLVAASVTYLGALPWHRCCALWRKWQRLCQGSEGSEGSLEPDDVSEALDGSAQDSA--
------------LPLVDMLSSGAESLQWGKHRHLGDLESQTRAVLLRASGQYSSHRLPLM
LDPDQLGEDWLRVLLEG--------PAHHKGGTLLDRGESMGCSWGGAEKEKKGDK---S
CRNNSHLYRAHTPK-------ALGHKELP-------EHET-----WEGTKQDRGAKK---
---SFTAELCVVDACSPLL--GDTIRLAAQKGECSFYPIISSPGETMSHQLKTKSQRDHI
PLKEIPASFQLYLSTRLPLAALKEGK-IVYIYKLKGQWQVLTVRLSSAVTHEAAFHCFLL
RV----------------SECEGSELSLRRS----LSEA-ESLLTQTNQNLEACGTAASA
LCCLGSKLQELAR--LAPHYSFSPGRVLHWAQR----------------VLQSEEWAQAA
REGK----PAEKV---------------LIRGVLAHVLPTIAPTDRY------ILRLLLA
IGQPSALEWLSFLGLLECS---GQVG

PF03028 // ENSGT00910000144015_1_Domain_9 (4227, 5032)

SPSCTQRPPWVGAQAWAELGQLERVPQFQGIRAS
LATHGSQWQEYFRLGSTIIGPVPS--PHFGHLTPFQKAILWRIVQPGKLGLVLTQMALCV
LGPESQEDWEEPADLSSLATPHVPIVFLLPKPEPHAPHFQPLPQILQLANSKGK-----E
VKVFTGGQNCSG--AEVRQLFITCRQEGHWLVLNNLHLEDPPLDHKLQYL-------MEP
NQVVFLLALLPTPSLFPTGDSVPPSPDYCLWIIIQEDSLNSIPVDMRYSCLPVPGGPPSN
LRPILQQNCPELEENLEEQPDRVKALQLLLLHSVLLRRQGYSRSAQTHSYSWYRSFPTLL
CCYGNHIEISVYGPMISLRVSLGSVIYGGHIVDEGDALSVAGLTNECLQDPAGHPTN-RG
PSNLLQVFLALPGKASGPWLSSIQSSIEKVSPSSEAAALGLSEGVPSSTYQACGLEALSK
LLITQDLWTSGASNGS---SLGPTKLEALLLERQRELEATQELAPQRRSDIS---TDTPI
VPAGERAQQPLSRFLQVEWDLLRTLVIQA------LHNVREAMSPCDCHVCQQVRRALSV
GLLPQGWNKYCPLGSLSLTDWVRELHLRLKLLFSYRSS-----PSLLNVTFNLSAFQHPT
WLLHSFLRARALAESK------DLDHRGTEGPELRAGGVLGIRESTITVNGTFSDWQVSG
RTLPTADNMAL-RVGGLHVQHALWDTRRALLQETLCPKLCALPDVSIRALPKHQLPVTHS
PLLHHYLCPVYPGGDPGGPAQLREAAILLLPLPSRIPPSVWSQRRVHALSLLS-

------------------------------------------------------------
---MKRHPQSW-LSSRPLPPIPPRPGEAPKQRAWNWQLEPELWAKSLRQQLNVQLLSALE
EKRAVS------SDSLESW-HSVCSLDSSRPGPWPFQTKQRKVLTAAPDLERPRALQLLL
AELQTLFSAVLQDRSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
QLDLLDAIDHALPPDSSLSHSASHADCHPQKKRFHRGPPCPPCPFVQTRWGGQQVKQELA
TWLRPLTLPELQHCLGIVGAEVALEEAQWLGSLSLLPLALATDIPVQYKSSDANSVDEEP
VGSK----DLDYEVSGEKPFQKRSSSFSSETFFSGSEVLSILDMERYRNKIHFLYLNVAP
SRYFRPYNLVVVPAKSVNPEHYIFSPFGILHVHPVEGNEALTLGAWHHQCILWQQLQLIP
FFKYCLVRKAFACWRKSVRWQGLCRLRTFLGNHLLSAVPHFGAGLLHINRLLQELHSVSW
LPQEPDRCYELLDLKKALFKERRKALQLLRRCLNLCTSILQLIHEDTYHMQQGLQERVQN
SHRIRTGQGSIYLLKVQRQQLEQKLKQAETWLLQLGKFARLVSYMICQNLVTILEDEITS
FVANSLQAPRQKPFLSSQLVCGEGCQLSPMPSIESMTEILSEGLHSTKASALKVCTLGSL
GI----PPSH----PRKDNLDSELLTPKFQGQPSHAVRIFCGPNVGLLWPWKSHPITDIL
EVRGSRLRGQYLPPNYHQLQEDLDNNLGIQEALTTQQALLEGMTQEVQEFCREHRWITEV
YEFLQAWGPQKLEDMRGCPVASYVTLVSQLSAWQAHVSNMPVQLLTKGSLLLLSCREVQA
ELESKLDSMKEDILTQVQNECWSRSQQLMTELTGFIQVFQTISTDIHSIALCSQKVNEAN
EEFIQLEERIEYIRSLHEFIRNYFNIFSAENEALDNS-----------------------
-------LLDMWEAFQFEKTQASEYLLSKQYAIVPKLQQLMAAALAELEGLLKKALSGPF
MDPTQEQKSTESKLISMEHQFENTARHLGELHHAYVTFTGDESPVPLPVCGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1599)

LQQH
IWHLYRTISETFSEWKCIAFVKFSLSVAQEKTDGWLTEAARMSTTLGVHSPVLQRCMRML
EEFRGYLPLLTKLGSSQRQNLNYQSLMRALGLSNLQSMELLTLGQLLTCPLLEFADR--I
NQVWQCDNERTRAQESLQQLQQDWEVRQLRLLNFILYVPYESSASEHSKKQ---TVPSPQ
WKAVGKDSGTFILSDYGSLQDSIQKSLQSLFKVLAIQKSGDLYKMALEWMTIMQSLG---
ALLELWMSFQQKWIFLNKVLYEMKIQFPSAELYTRFKAVDDQYRVLMRISVADPLVLSLI
-LPSAKRSPYFQGQQLQQQLQAGSVELEGIIMALETVLYGVCAHFPRLFFLSDSELVALL
AAPLEPCEAELWAHRCFPPMHAVSFKSSPSD-EKNMDDQES----SSSRQTQVEALAVLG
EGGEVVKLQGPLLLYPDLPKWLASLENCLHLALVCMLQ

ENSGT00910000144015_1_Linker_1_3 (1599, 1791)

DCVAARLEVRPSIGETFKK---
LPEQSQSA----LHPNIQHWLDLVQAFPWQCVMVAEEVVWRVEMEEALLELGTLATTPRH
IHKLEVLVQFMRAQRSSQGGQPLLSVRQASLLSALLVMAVTHRDIAQLLEKHQVSDLTDF
HWARQLKYHLGSPHLIPESPLQSLKTVVS-TEPSLTPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLLERPVLVLLLALEEVACGTLVGPDGVGKTSMVNSLARALGRQLVMMPCLPQIQ
ARCLSNYLLGALQGGAWLLLEGVEHLPPGLLSALGQRLAELRCLCAPLYQEASQSISTID
-------PTKPQILGSGSFEKHHVSVRLGYGCLLTLRALSPAVPANLHLLLRPVALAL-P
DLQQVAELTLLGAGMQDASRMATRLCKFFSLESELVSGPVPCRLPLLKQILEETIQTLS-
--EEFKPQDSSSLVGIEEAALLRALLHSSLFSSLDGLRLHHLRELLRGIFPTAVQVLAEP
MTRRRMKSLVVEELQQVDLHPSPDLMGSLEQLSEALNWASGIVLLGPAGSGKTTCWHSLF
KIQNRLAALEKT----STQRYQSVEITHMYPSVLSSQEFLGWLEGSHWHCGIFPRVLRAA
LHYRSTGPKEQAEEPLRIQHWVVCDGASSAAWLDSITCLLSDPPQLSLPNGQQIARPPGT
FLLMELADATGMSPMLVSHCALVWCSGEQTWHSMLSTLMAALPHEYHLPPHTVAALNQLV
DGLVPATFRFLTRKGASSLLQVH-GHQAVCPGVAEVTSLGRILRGLLDLHLHLDEEKK--
--------AQDLEDS---SLKASKSSYA-NWPKADSDDGPNQDREHLLTLSSFLFALIWG
FGAH--------------LPS-RS-WPFFDVFIRSSIGSLSNYPELPPIALVFELHVNPE
DGTLVPFTGHYLSSRIRGTLGTFHP

PF12775 // ENSGT00910000144015_1_Domain_5 (2546, 2783)

STQTERLLYVVDLLLSRGQPVLLAGEEATGKSAFV
EALVEPSHPYIYSPVHPAFCSTHFRLLLSRGVQDQAQA-SPWSAHHQDPKGSLLFLLEDL
HLASSDAEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATTTVPGGCGHPLCPR
LFRLFTVLALGSVTQATLLSRHTPSIQAWLERFPSVEQVGILGKALVQASVEAWEAVCRR
FMPSPLHPHYRFSLHSVSHLLGSLQLLPSKVGSQVFEDCFYDKEHLYRVSGLQGTCLTIM
MTMRCVVRLWLHEAQRTFCDRLDSPRERSDCANLLLEIAQRVFCHGPGRQPLGKDHKEEE
E-----EEEETVPEVESEGELAQWENM-----SNSNSETEEEEDPYGLQATPSSYSTDPS
LAPSI---K--TVSLEPMESISH--KAEQEESRRASSCKLQSEE-SNIWWQKAGP-MDMV
TPL--LLPVLLLRPKEKPSDLVFCQELILGSNSEGPN-LYLERQWVRLEKQLATSAAQLR
LSPHLVRIRPLAQHVARLVRVLSRPRQHGLLLSGALGTGRRTAITLATSICQAHLFHLPT
-GPEEAILRCLRDASWDAGMLSHPVALLVPKSVDLTTLYRLAALASVGNFPEQYTEADLD
SIEEHL-PRENLGIKYNTKKEIV--LFYQQVCSHLHM-FFLMGD--DQAQKKLPSTFFLR
LLQLATASIDHYESWDQASLVRVAQYHLEGA-ESLPLDDGSFKCPDLQASIPSVAKAMAL
IHLSAAYYHEHLCPVLPLVTPKTFLDFLDTFLLLQQKMILKMKNRAKMIQNALENLRILV
EQHRVRTTLVINLEHQLKDSQKN------------LNQAQQQLEQSKLLYKQQLSEC

PF12777 // ENSGT00910000144015_1_Domain_7 (3418, 3687)

RHQ
ENLTENLAKQRDALQAQHEAFLDQMGKAFLGPLSQLQVADFEEIRSYRAPPESVVRVTDA
LCELFHRETGWASAKQLLCTEDFYQELVFFPKEKMTDLELVRLNQALKAPGMSDAALRAV
SVPAASLATWLWAVLRYRLAQHRGLPTGLLLRQVEATLAREQARLGHYQLQAQEKLEDIL
TWTKKVQDAHAAHRCMLGTLTLAQHGRYQKWTVRPALITPIHTWTMQLQNLKGHCLTVFG
DALVCSAAIVYLGPFPPPRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSGIVV
PPKTPLLPTRLPFRILSLLSCSSEQNRWDRDLKPQVKSARLAGLLLRSCTHYHSCRWPLL
LDPSNQALMWLSPLPLEENSCLASAPME-----------------------GGGKAGVVT
QS--KEQAQAQKAKEQENEEEKEEH-----KGEEEKEEEEKEEEEKEHEAESQGSKPACE
TPSPPLLCLSVLSGTDPKL--GPRLREAAASGQPVLLTNME--LGLGCPELQWLLQREQL
SPPHVQPGFCLYLSTTLPLHALEK----VLGCELLKGLNVLDLGLNLEVLENQVLHEVMH
RECPELEIRWEDLKTRALDACEAIEAAEEQLLTMLLFQ--NPLHEKPTKFMRDIVRAQAK
ICQMQAHYEELKEQKLQEVVLWVPYQQVVWHGIAIVKTLSTLQNSLPFFHMSAENWLAAI
RQALDSMKPHDIQHREDLASHLLQLKAHLTRQLLGITLTALGLTQVPLVGALGALALLQV
TENAPKLERLALWPGLAASPSTGYQKPDPGVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLTPRAWHECGILEVLPPFVGLRAS
LADRSKVWQDYLSLHSTVLGPAPG--PSSEPLSLLQKLILWRVLRPESLAGALADLTTSL
LGRPLDENLGIPTLPFEQSQATQPILILLPPPGHPTTTLHPLTVIQKQAASNK-------
-QVIALGSEAWNPVSDVVSTLNQAMLEGHWLVLDNCHLMS----HWPRELLQPLLGLLDG
AKVVSDQEQALLLAQAESRNAATVHRDFRLWLIASAEASASLPAVLSQHCMPVFWDQSLE
LGHILIHSLELAQQGSHMQS-PTQALPLLLLHGLLLHRQLYAARLQAHRGRWSHLTLTQA
LETQEQLWASLSNPSTAMQELAASVFYGGSLGDTKDREALISLTQACLRPRSHSWVQPHT
PQYLLATLMPSPDLGKLDAMAECKAQMHLLPTPSEPQTCGLSEGPQAWLLRRQSLTLLRV
LQQSSTTWVPAARGGA---RRTERRLWQRLVQAKQKLESLQALLSNHTRRDPS---S---
AVRGRGTRRPLEDFLEAEALELSQLVGTLQRDLDCQLRQLKGEPPCPSHRCAAVAHALWT
GRLPAPWRPHAPSGPQPPWQWLRQLSSRGELLVSYLGA--NAGTEVSERVFHLSAFRHPR
RLLLALRWEAALEQ-----RLSNLKFPGSEGPSSC-----PVPHRHRELSGSPLHLRVEN
GPSPMVPETGL-LLVGLQLLHAKWDPAAGALQDCASSQPSPLPPVSVSARAQRAGVLSRA
AGPAVYSCPVYRAGPLGGTKLHSRNILMHIPLPTKLSLAACVQRRVHVCSPPLP

------------------------------------------------------------
--------------------------------------------------------MVPE
EKRVGLSSDETSSDALKSW-HSICVL-DSKEEPLARQQKQRQFVKPATESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAINQAFPPDSSLLDSASHADCCPQKQRLHHRPPCPACPFVQARWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRKETRSQLDYEVPREKTLQKSSTGFSPETSFLGNQVMTALKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNAEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQKALAKEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRAGQGSIYLQRVQRKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILEEQITS
FVANILQAPRQKPFLSSQLVFDDHDQLSHVPCVENMIQILTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKTEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVHGYRLRGQYFPRNYKQLEEDLNNNSQIQQALNIQQVLLEGVLWEVQEFCREHHWITGI
YEFLQSWVPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPVELLTKGKLLLLSCRDVQT
EMESKLDSIRKDILAQVQNECWSLSQQLMTELTNFMHVFRIINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFRGSPIPPRPPPPRPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIIPKLQQLMAAALAELEGLLGKALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSELHHAYVIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTEGWLTEAARMSTTLGLNSPVLQHCMRIL
GEFRSYLPLLAKLGSLQPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIRQLQRYWEVRQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIQKSGDLNKIALEWMAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVRFKSCPTG-EKNMDDWES----SPNAQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFLRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTTS-SEHSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHSLYAPLYQEASRNTSTID
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIQTLNV
AKEEPKCQQPRSLAAIEEAALLHALLHSPLFSVLNGLHLHNLRGVLCALFPSASQVLAEA
MTYKLMKALVVEELQQVGLHPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEET----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESMGIQHWIICDGASSAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADATGMSPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNHMA
EVLVPATFRFLARQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDPHLRLKEEKAP-
--GPEDLSCSDSVAQ---SFRSSKSSFL-NRSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2781)

QTERLLYVVDLLLSRGQPVLLAGEAATGKSVFV
EVLVEPHHPYIYSPIHPAFSSTHLRLLLSRGIQGQTQA-SPQPGHHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVEREHALARALVRASVEAWEAVCNC
FMPSPLHPHYHFSPHSVSHL

ENSGT00910000144015_1_Linker_5_6 (2781, 3071)

LSNLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTRLTIM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQNLGKDHEEDE
------EEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVATGSNSSDPS
LTPSI---G--PVSRGMRESISH--KIRQEKGTRASNYRLQVRRSFKTWWQKAPQ-MDLV
SPL--LLPVLLLHPQEKPSDVVFSQELTLGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHS

PF12780 // ENSGT00910000144015_1_Domain_6 (3071, 3329)

MAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQTHVFHLPS
-GSEEDILQCLRDASWRAGLLSQPVALLVPSGVDLTTLHHLLALATSGSFPGQYTEADLD
SIEEHF-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEDA-RSLPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFL

ENSGT00910000144015_1_Linker_6_7 (3329, 3415)

DTFLMLQQQTILKIKNKAQRVQNALENLRMLI
KEHGTHANLISDLEQQLKASSKS------------LSMFQQQLEQSKLLYKQQL

PF12777 // ENSGT00910000144015_1_Domain_7 (3415, 3687)

EECRHQ
ENLVEDLAKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKITDSQLIKLHLILKAPGMSDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLIREQARLGYYQFQAQETLENNL
ALAKMVEDAQASHNCVAKTLSQAQHGQYHKWPMKAALLMPMHAWTIQLQKLKGRCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKNPLLATHSPFNILSLLSSASEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALMWLDPLPLAENRCLAPAPTEGRGKGLM----RNQNTESK-MDMKEEDDDSED
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTSLSLCAMEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RECPELETRWQNLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNMVRAQGK
LCQLRAHCEELEGQKLQEMVSWAPYRPVVWHAIAMVKALSQLQNLLPLFRMSPEKWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVSGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMGAPTMPFKHSRATQPMLILLPLPGHPTATLHPLTVIQNLAAKYQQ--GQKH
LQVIALGSEVWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLGQPESSNVATVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTEDREALFSLTQACLSPSSRNCVQPHT
PQSLLARLMPLPELREPDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRVLLSA
LQRSSPVWVPESRGGA---QLAERRLRQRLVQVNRRLESLQDLLTNLVRQDES---GAPR
SVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADANSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGAVSS-----PLPYKRLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPPP
ADLTVYSCPVYMGGPLGNTKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

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----------------FEKSQASEFLLSKQHAIVPKLQQLIAAALVELEGLIDKALSGPF
MDPAQEQRSTERQLISLERQFQNTASHLSELHHAYATFTGDDSPV

PF08393 // ENSGT00910000144015_1_Domain_1 (1126, 1605)

PVPVCGTRPIVQQQR
IWHLYRVTSENISKWKCMAFAKFSMTVAQEKTDSWLTEAARMSTTLGLHSPVLQCCMRVL
EEFRSYLPLLTKLGSLQLQ--NFQALLQALGLGSLCNMELLTLGQLLTCPLLDFADR--I
NQIWQCENERIHAQETLRRLQRVWEARQLRLINFILHVPYEPPTLERSKKQ---VTRSPQ
WEVVDKDSGTYILSDYSSLQDSIQESLQVLFKILAVQKSGDLNKVALEWVAIMHSLS---
ALLDVWVTFQQQWIFLNKVLHEMKIKFPSPDLNSRFKATDDQYRTLMQISVDDPLVLSLT
-VPSVKRSPHFQGQQLQQLLQAGSAELEGIILALKSVLYRVCAQFPRLFFLSDSELVALL
AAPPEPCEAQLWVRRCFPHVHAVSFTASPPD-EN-KDDRES----SPNASSQVEALAVLG
AGGEEVKLQRSIPLHPDLPKWLAFLEKCLRLALVHQLQGCVASRLALGPSLDEALKQ---
LPERGQLP----PQLFAHPCLCLVQAFPWQCVLVAEEVVWRAEMEEALLEGRTPALVPKH
VCKLEALVHFIQAQRASQGKQPLASVRQTSLLSALLVMAVTHRDIAQLLQEHQVSELTDF
HWARQLKYHLGSPHIIPQSPLQSLKTTAS-AETSPSPAACWVDVLGRSFLYNYEYLGPRL
GSLPSLLPERPALVLLLALEEVACGTLLGPDGVGKTATVKSLARALGRQLVTMPCLPQIE
AQSLSNYLNGALQGGAWLLLEAAQRLPLGLLSALGQRLVELRHLYAPLYQEASRSTSTVD
-------PTQPQLLGSGFFEKHHVDIRLGYGSLLTLRSLSPAVPANLRLLLRPVALTL-P
DLQQVAELTLLGAGMREASRLAARLSKFFSLELELVSAALPCRLPLLQHVLEDMIQDLNA
TKEEPQSQQPQSLAVTEEAALLRALLRSPPFSILSGIHLHSLQELLCRLFPDARQVLAEP
AVPTPRKPLLVGELQQIGIYPSPDILGSLEQLSQALGRALDVLLLGSAGSGKTTCWHSLF
KIQNRLAAREDA----STRGCQPVEITHLYPNVLSPQEFLGWLEGPCWHHGVFPRLLRAA
SPCKTVGPKGPPQESVGIQHWIICDGVASASWLDSITCLLKDAPQLSLPNGQQIARPPGT
FLLMEVGDATGMSPTVVSQCALVWCGGEQTWQGMLSVLMAALPHEYHLPLETVTELNHLA
EVLVPATFQFLACQGASSLLHVH-GQRAVCPGVAEVTSLARILRCLLDPHLRIDEGEKAH
--ISDDLSFSDPVAR---SFQSSKSSSL-SPSQADSDGAPSQRKEHLLAISSFLFALIWG
FGAH--------------LPS-RL-WPLFDTFLRGSISCLSNYPEPPPSALVFDLHVCPD
NGTLVPFTGHYLGSRLKGTLGTFNPSPQTERLLYVVDLLLSEGHPVLLAGEAASGKSTFV
EVLVEPHHPYMCSPIHPAFTPIHLRLLLSRGVQGQARA-SPWPGQHLDSKGSLLFLLEDL
HLAASDPEKSCQPVLETLRQAIDGTVYAHSTLELQTLQPVVNFLATATVPGFCERPLCPR
LFRLFTVLALGSVTQAMLLSRHTPSTQAWLERFPSVEREGVLAKALVRASVEAWEAVGNC
FLPSPLHPHYRFSLHSVSQLLGSLQLLPTRMGSRGFLDCPNHQEHLRRVSGLRGTRLTIM
MAMRNMVRLWLHEAQRTFCDRLDSPRERSCCAKLLLEVAQSVFCCGPVPQNGGKGEE---
------EEEERVPEVESEGELAQWEEA-----SNSDSETEEEEDPYGLQVTTGSPANDSG
LAPSI---T--PVRRETIESLSP--KISQEESIKASGYKLQLNK-SKNWWQKTSR-MDLA
SPL--LLPVLLLRPQEKPSDLVFSQELILGSNSESPS-LYLERQWESLEEQLSTSAAQLK
LSAHLARCHSMAKHVARLVRVLARPRQHGLLLSRALGTGRRTAITLAASIYKARLFHLPS
-GSEGAILQCLRDASWHAGMLGQPVALLVPKGVDLTTFHRLLALATSGSFPDQYTEADLD
SIEEHL-PRENLSVKQNIKKETLLQRFYQQVCNHLHM-FILIGD--DQTHKELPSTLFLR
LLQLAIASIDRYEPWDQDSLISVVRYYLEGA-QNVSTDDDSLKCPDLQEAIPRVAKAMAL
IHLSAVSYYGHLCPELPLVTPKTFLDFLDTFMLLQQQMTLQIKNKFQRIQNALDNLRMLI
EKHNAYTSLVFNLEQLLKGSRKN------------ISLLQQQLEKGKGLFKQQLADCQQQ
EKLIENLTKQRDALRAQHEAFLEQMGKAFLGPLSQLQVADFEELRSYRVPPESVVQVTDA
LCDLFHCETGWASAKQLLCTEDFYQELVFFPKEKMTDSEVIKLTQALKAPGMSDAALRAV
SIPAANLAAWLWAVLRYGLAQRRGLPTGLLLRQIEATLAREQARLGHHQFQAQETREHNL
DLAKTLEEAQASNNHMIEKFSQAQCGQYHKWPIKAAPLTPMYSWTTELQKLKGHCLTVFG
DALLCSAAITYLGPFPPVRRQELLDKWLALCRGFQ---ETLGPDDVAQALKQKQKSVVVP
-PKNPLLSIRSPFSLLSLLSSESEQLQWDRDLKPQAKSARLAGLLLRSNSHYSSCRWPLV
LDPSNQALIWLNPLPLQETRCLAPGPTECREKGFV----RNQEEEEEDAMEE-EDDSREE
CDEAKDKTKEQK-TEDREN--------------------------EEEETEREGSRPASE
TGSLPLPHLRVLSGADPEL--GPQLQEAAASGLPVLLTNME--LGLGCQELHWLLQREEL
SLPQVQPGFCLYLSTTLPLSALGK----VLGYELLKGLNVLDLGLNMDVLEDQMLHEILC
IECPELKSRWQDLKTRALDSCEAVEAAEERLLLLLLFQ--NPKYQKPAKFLRDMVRAQAE
LCQLRAHCEDLEDMTLQEVALWAPYRRVVWHGMAIIKALSPLQHLLPPFRMSPDNWLVAT
RRALHSVRHRETHQGEDLPSHLLHLRAQLTRQLLGSTVAALGPTQVPLVGALGALALLQA
ARKAPELERLAFWPGLAASPSTGY

PF03028 // ENSGT00910000144015_1_Domain_9 (4225, 5031)

RKP--GVARPAWLGLRAWHECGMLELLPPFAGLCAS
LAGHSTVWQAYLSLSSTVLGPAPGPRPGPDPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENLGASTIPFECSQATQPVLILLPPPGHPTATMHPLTVIQKLAARHEQ--GQKH
LEVIALGSEAWDPVSVVVSTLCQATHRGHWLVLENCHLMP----RWPKELLQPLLRLLDG
ARVVPDLELELLLAPPASRSVTTVHRDFRLWLILSAEAIASLPAVLTQHSMPVFWDQSLE
LGHVLSDSLELAQQELSVQP-PARMLPLLLLHGLLLHRQLYGMKLQAHRGRWSQVTLIQV
LQIQDQLWASLSNPSAAMQELAASVFYGGPLGDKKDREALISLTQACLSPSDGSWVQPHT
PQYLLSTLLPSPEPGELDALAECKAQMHLLPTPPEPQSCGLSAGHQAWLLRHQSRALLSA
LQRSLPIWVPASRGGC---RRAEKRLRQRLALAKRRLESLQALLTETASQEES---GAGW
AVLGLSSRRPLQAFLQTEVLELSQLAGALLRDLDCLLQQLKGAPPCASPRCAAVAHALWT
GRFPPPWRPHAPAGPQPPWHWLRHLSRRGQLLVRYLGVD----TKVPERIFHLSAFCHPR
RLLLSLRWEATFAMATLNQRVPSSNFPACQGSSSS-----GLPHKHQELNSNPLHLQVVN
SPNPTVPEMGL-LLIGLQLRNAEWDPLAGALQDSTSSQPSPLPPVSVSAQAQGPSDLPPP
TGLSVYSCPVYMEGPLGITRLHSRHILAHLPLPTKLSPTTCDRRRVHVCSPPLL

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-------------------------------MSLESVLYGVC

PF08393 // ENSGT00910000144015_1_Domain_2 (1483, 1602)

AHFPRLFFLSDSELVALL
AARLESCEAQLWVQRCFPHVHAVSFKSCPTG-EKNTDDWES----SPNTQTQVEALAVLG
AGGEEVKLQGPLPLYPDLPKWLASLEKCLRLALVHMLQGCVAARLAQGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSMH
MRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHHVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTVIS-SEPSLSPATCWIDVLGRSFLYNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKTAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHQLYAPLYQKASRNTSTID
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNV
TKEEPKCQKPRSLAAIEEAALLHALLRSPLFSILNGLHLHSLRGLLCALFPSASQVLAEP
MTYKLMKPLVVEELQQVGLHPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSCLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESVGIQHWIICDGASSAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADTTGMSPTVVGCCALVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNHMA
EVLVPATLRFLTRQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDPHLRLKEEKAP-
--GPEDLSYSDPVAQ---SFRSSKSSFL-NRSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RY-LPGWGMGDAEG------------------------
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---MKPHPQSS-PPTLPMPSVSCRPGQTQKPKDWNWHLDPELWARSVRQQLNTCLRFILE
ERKVPLSPEIPWFDTLQSG-LAGCSC-SGQEHSWDCQEKQ-EHLKAVVESEQRNMLELLL
SELKSLFSAVLQDGSCEAWHYLHAVLGLLPPYREMLAGQLELLPFLEQLYCWAPKVQAWL
QLDLLDAIDKAFPPDSSLLHSSSHVDCSPWMKRFHRGPPCSACPFVKARWDQQQK-KELA
TWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLPLALATDIPVQYESSDIGHAEPAP
AGR---KPQLASEAPE-KALKRKS----PRTSILRSQVKSLLKGDWSQKKIHFLYLNVAS
DRHFNPYKLVVVPPNKVNPEHYIFSPFGILHIHPVEGSETMSLATWHRDTALWHELQRIP
FFKNCLLRKALTCWKKNVRFRGLHRIQTFLKTHLLLAIPHFGAGMLHINRLLQEFRSVSW
LPKEPDKSYVLRDLKKAIAKENHRALRVLCHFLNLCASILQLIHEDTYQMQQGLQERVQN
WNRIRKSQGSIYLQRTLCRHLEKKLKQAETWLSKLGMFARLIDYMICQNLVSILEDEITS
FIANNLQAPRQNPFLVSQLVFDDNGQLSPMPRVESIIQSLIKSLQSIKTSALKVMQSTDL
RTSREPLYSE---DNKDQDSNTEFPMPKFHGKSSDAVRLFCGPNVGYVWPWKSHAITNVL
EVRGHRLRGQYLHPNYDHVQEDLDKNAGIQQALAVQQALLEDMRQEVQEFCNKQQWVEDI
YEFLKAWNSQKLEDLRGSPISDYVKLVRKLKNWQERVSNMPVELLTKTKLLLLSGRDVQE
ELESKLNNLRKNILEQVKNECWSRNQQLMKKLTEFLRVFQTINLDIHAIAQCSQKLNEAN
EQYCHLEEQVEYVRSLHDLIRNHCVLFISENETLDIA-----------------------
-------LLDLWEAFQFERSQVSEFLLSKRHAIVPKLQQLMAAALAELEGLLVKALSGPF
MDPSQEQRSTEQQLGALENQFLNTLSNFNALCYAYRSFTGHKTTMSPPASGNRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

LQQR
IWRLYRIIHENFSEWKCVAFSKFNLSMAREKTNAWLTEAARLGTALGQQSPVLQRCMRML
EEFRAYLPLLIKLGSLELQDVNTQSLLRALGLGGLQSLDLLTLGRLLNCPLLEFADR--I
NQVWQRDKERIHAQEILQQMQQYWEGRQLRLLNFILQVPYRPPTSERSKRP---ALRSPQ
WELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGQLHKIALEWVTIMYDLG---
ALLEVWVSFQQKWIFLNKVLHEMEIEFPAAELNARFKVMDDQYRTLMRISVADPMVLSLI
-VPNTKRSPYFQGQHLQHLLKVGSVELEAIIMGLEDVLYGVRANFPRLFFLSDSELVALL
ASPLDTSEAKPWAQRCFPYIKAVNFRSKSTN-KEN--NDKD----SKSSIETVETISVLG
ACGEEVKLQEPLPLYPDLPKWLASLETCLRLVVVNLLQS

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVATRLAQGPSLIKALKA---
MPQQRQMS----TQLYVQHWLDAVQVFPWQCILVAEEIVWRAEMEEALLESKTMRLSSVH
VRNLEVLVQFIRSQRSSQGEQPLPSVRQTSLFSSLLVKAVTHRDIAQLLEKNQVSDLTDF
HWVRQIKYHLGSSHLNLKSPLQCLTTTASTEEPSVSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYMGPKL
GPLPSLMHERQVFILLLALNEVAYGAVLGRDGLGKAETVNSLAWALGRQLVIMPCLPQIE
FRCLSNYLNGALQCGAWLLLENVHQLPSGLLSALGQRLDELHHLYAPLYQKASKNISTIN
-------PTKHLLLGAGFFEKHQVSVRLGFGCFLTFHSLSPDVPANLHLLLRPVALAF-P
DLQRVAELQLLGAGVRDASRMATRLSKLFSLERELVSGTLPSRLPLLKQVLENTIETLNA
SE-ENKSQQPHNLAAAEEAALLRALLHSPLFTILDGLRLQKLQELLCGIFPNASHVLAEP
VCHRLMKSVVVEELQQLGLFPTLNTLTSLEQLSEALSKASGILLLGTAGSGKSTCWKSLF
KIQNRLAAMEHT----STKGFQSVETVHLYPSVLTSQEYLGWSEGSSWRYGIFTKLLHAA
PYCKTVGSEEKSERFTGIQQWIICDGAPNHAWLDSITCLLADPPQLSLPNGQQIARPLGT
FFLIEVAEAAGMSPTVLGRCALVWCCGEQTWQSMLSVLITSLPHEYHLQQETIVQFNHLA
EVLVPSVFRFLTRIGASSQLQVH-GHQAVCPGVAEVTSLIRILRALLDPHLHLFEEEKPH
--TKEDFSGTDLVTQ---NFISSKS-----KAQSDRISVYKKERRHLLAISSFLFAIIWG
FGAH--------------LSS-RH-WPLFDDFMRKAISSLPNYPEPPPSALVFDLHINLE
DGTLVPFTGQYLSTHVKRSLGSFQPSSQV

PF12775 // ENSGT00910000144015_1_Domain_5 (2550, 2783)

EQLLYVVDLLLSNGQPVLLAGEIATGKSAFV
EVLVEPNHPTIHRPINPALNSAHLRNLLSRAVHGQTQA-GSFVGPHQDSKGSILFLMEDL
HLAAFDPEKSCQPVLETLRQAMEGTIYSHNTLELQTLQPTVNFLATATVPGYSERPLCPR
LYRLFTVLALNSMTQDTLLSRHVPSIQAWLERFPSVEREHTLARALVRASVEAWEAVCNC
FMPSPLHPHYRFSPHSVSHILG

ENSGT00910000144015_1_Linker_5_6 (2783, 3071)

SLQLLPTRMGSRGFVDSFHHQEHLRRVSGLRGTRLTIM
MSMRVMVRLWLHEAQRTFCDRLDSDRERSHCVKLLLEVAQRVFCSVPGSESLARVCEEEE
------VEEEKVPEVESEEEIAHWEIL-----SNSDSGSEEEEDPFGLQATTGSFLSESG
LAPLPI--K--SVNKENTENVSQ--VAQQLEDIRNSNSKLQSET-HKRKWQRAPQ-TDLS
LPL--LLPVLLFYPQENPSDLVFSLELTLGSNFESPN-LYLERQWENLEKQLAASAVQLK
MNSDFAQCHV

PF12780 // ENSGT00910000144015_1_Domain_6 (3071, 3277)

MVQHVARLVRVLARPRQHGLLLSEFRGTGRNTAIILASNICQARLFHLPF
-ESEEAVFQCLRDASWHAGVLNQSVALLVPDQVNVATFCQLLALATSGSFPDQYTEADLD
NIEEHL-PKENLVNKYSIKKDTVLNRFYQQVCSNLHM-FFLMED--DQVQKQLPSTLFLS
LLQLTIASVDRYEPWDQASLVRVAQFRLEND-QSLP

ENSGT00910000144015_1_Linker_6_7 (3277, 3443)

LDDGSLKCPDFKILIPNVANIMAR
IHGSSAYYHQHMCPALPLVTPRTFQDFLDMFLQQQQQMVLQMRMRARRIQSALKTLRLLV
ERHSTQTSMLTDLEKQLKGSYKGMELKDLDLCSQNVGMYQGQLEQCKILYKQKMAECQHL
ESLIENLTRQHDALKAQQEAFL

PF12777 // ENSGT00910000144015_1_Domain_7 (3443, 3687)

EQMGKAFVGPLSQLRVADFEEIRSYRAPPESVVKVTDA
LCDLFHHETGWSSAKQLLCTEDFYQELVFFPKEKLMDSELAKLSQALRAPGMSDASLRSV
SIPAANLAVWLRAVLRYGLAQRRGLPTGLLLRQVDATLAREQARLGQFQFQAHDLLQQTQ
FLTKKLEDAQLSHNHVVETLNQAQCGHFHRWPMKSALLTPMHMWTTQLQKLQEQAKTVFG
DALLCSAAIVYLGPFPPQRRQELLEKWLSLCQGFE---EALDPDDVAQALRQ--KSVRV-
-SKNPLLPTRTPFRILTLLSCGSEQHQWDRDLKPQAKSARLLGLLLRSHIHFSSSRWPLL
LDPSNQAIIWLNPLPPKQNKWLEQPPKESRAKYHV----TNQDSEDETEDELESENN-ED
EDEVSEQREEHKTEENES--EE---------ENKQEEQETEKENEAESTSSGSSSSPPSE
TQ-CLPSYLTVLSGTDPEL--GPQLLEAAANGLPVLLTNME--LSLGCQELQWLLSKKNL
IPPYVQPGFCLFLSTTFPIHALDR----VLGYELLKGLNVLDLGLNMEILEEQMLHEILC
RERPELETRWQDLKVRAAENYEAMKADEEQLLVILLRQ--NKMRQKPSRFLREMVRTQAK
ICQLNAQGEELDEQKLEVAALWAPYRQVAYHGMAMVEALSSLQNLLPFFCMKSENWLAVI
RRAIDSMKSCDSYHGEDLPSHLLRMKIHLARQLLINTVVALGLIQTPLVGAFGALAMLQV
TKKTPKLERLALWPGLLASPSSGHNIQIPGVTRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLSSRAWEECGALELLSPFAGLRAS
LASHSDVWQDYLSLSSTVLGPAPG--PNSEPLSLFQKLILWRVLRPDCLVGALADLTTSL
LGRPLDEDLDAPTMIFDHIQPTQPILILLPPPGHPTATLHPVTVIRKLAAS--E-KPQKR
LHVIALGSEDWDPVSTVVNTLSQAMLQGHWLVLDNCHLMP----FWPRELLQPLQGLLDG
AKVVSDSEL---IAEPESRTVATVHRDFRLWLIASTEASTSLPGVLTQHSMPVFWNQSLE
LGRILIDSVD-SQQELSTQS-FTQTFPLFFLYGLLVHRQLYGLKLQAHRGRWSQVTLTRV
LQIQEQLWASLSNPSAALLELAASVLYGGPLRDLEDRETLVSLTGACLNPRNMNWVQPHT
PQYLLATLMPSPELGELDARTDCKAQMHLLPTPSEPRTCGLNEGPQAWLLRRQSRALLSA
LRQCSSTWVPTVCGGI--VQRKERRLRQRLVQAKKRLVALQALLTNNR--YRSGQCVTPW
AVLGPNARPPLEGFLETEVLELKQLVGMLLRDLDCLLQQLKGKTPCTSSRCAEVAQALWA
GRLPQPWRSHAPAGPQLPWLWLRQLSRRGHLLIQYLDSGISENANGPERIFHLSAFRHPR
RLLLALRWEAVLEN-----SGHSPKLPGHQGSGSG-----NLPPRRQELNNHPLHIWVEN
GPNPKVPKMGL-LLIGLQLQHAAWDQTDGALKDSFSSQPCPLPPVSVSTQSRGAKDASVS
AGLGIYSCPLYMTGPLGTTKLHSKNILMRLPLPTRLSPDTCIQRRVHVCSPTLT

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--------------FQPHELWQEPEGETQKQRAWNWQLAPELWARSLRQQLNVQLLSALE
ERRAGL------SLDAVS---------SENL-------ESWKFLTAETDSEQPTVLKLLI
AELQALFSAVLQDHSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVKAQL
HLDLLGAMAQAFPPDSSLFHGASHVDCHAQKKQLHRGPPYPACPFVQAQRGGQQVTQELA
TWMRPLTLAELQHCLGIVGAEVALEETQWLGGLSLLPLALATDIPVQYEE----------
---E----SFGYEVPGEKSFQERSS----STFFTGSEVLTLMDREKNLKKIHFLYLNVAP
SRYFRPYSLVVVPPKRVNAEHYIFSPFGILHVHPEEGSEAMTLGAWHHQSVLWQQLQLIP
FFKHCLVRKAWTSWRKTTRQQGLCRLRTRLGDHLLSAVPHFGAGLLHINRLLQELHSVSW
LPQEADRCYKLLDLKKALLKENRKALQLFHRCLYLCTSVLQLVHEDTYHMQQGLQERVQN
CNRIRAGQGSISLLKEQRWQLEQKLKQAETWLRQLGKFARLVNYMICQNVVTILEDQITS
FVANILQAQRQTPFLSSHLVCGDRCQLSPVPSIENMSQVLSEGLRSIKASALKVGILD--
-LLGTPGFSE----DEEESSDTEFLMPKFQHQPSHAVRIFCGPSVGLVWPWKSHPVTGVL
EVHGYRLRGQYLPPNYDQLQEDLDSNLRIQQALTIQQALLEDVMLEVQEFCSEHRWITDI
YEFLQAWGPQRLEDMCGCPVTDYIKVVEQLSAWRTHISSMPVEVLTKGKLLLLSCHEMQA
ELKSKLNGMRKDILTQVQNECRSRSQQIAAELTEFTQVFQIISTDIHSIAQCSQKLNEAN
EEYIALEERIEYVRSLHEFIRNYFNLFSAENEALENS-----------------------
-------LLDTWEAFQFEKTQASEFLLSKQYAIVPKLQQLMTSALAELEGLLTKALSGPF
MDPTQEQRNTESKLVSMEHQFKNTASHLSELHHAYVTFTGDESPVPLPACGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1599)

MQQN
IWHLYRVVSETLSEWKCMAFVKFSLAVAQEKTDGWLTEAARLSTALGMQSPVVQRCMHVL
EEFRGYLPLLTKLGSFQRQNLNYQSLLRALGLGSLQSVELLTLGQLLACPLLEFADR--I
NQIWQCDNERIRAQESLQRLQQDWEVRQLRLLNFILHVPYESSASKHSRKH---TVSSPQ
WKAVGKDSGTFILSDYNSLQNSIQKSLQALFKVLAIQKSGDLHKTALEWVAIMQSLG---
ALLEVWMAFQQKWIFLNKVLHEMKIQLPSAELHARFKALDDQYRMLMRISVADPMVLSLI
-MPSAKRSPYFQGQQLQQQLQAGSVELEGIIMALETVLYGVCAHFPRLFFLSDNELVALL
AAPLEPCEAEMWARRCFPPVCAVSFKSCSTD-EKNMDDQES----SPSRQAQVEALAVLG
EEGEEVKLQGPLLLYPDLPRWLASLENCLHLALVCMLR

ENSGT00910000144015_1_Linker_1_3 (1599, 1791)

DCVAARLAVRPSVSETFKK---
LPQQSQSP----LQLHVQHWLDLVQAFPWQCIMVAEEVVWRAEMEEALLELGTLATTPRH
IHKLEVLVQFVRTQRSSQGGQSLLSVRQASLLSALLVMAVTHRDIAQLLEKHQVSDLTDF
HWARQLKYHLGSPRVIPQSPLQSLKAVVS-MEPSLPPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLLERPALILLLALEEVACGTVVGPDGVGKACIVNSLARALGHQLVTMPCLPQIQ
ARCLSNYLLGALQGGAWLLLEEVQHLPPGLLSALGQRLAELRCLCAPLYQKVSQSASTID
-------PTKPQILGSGLFEKHHVSVRLGYGCLLTLRALSPALPANLHLLLRPVALAL-P
DLQQVAELTLLGAGVQDASSMATRLCKFFSLEHELVSGPLPCRLPLLKQILEKTVQMLNM
TKEEVKSQDPSNLAATQEAALLHALLHSSLFSSLDALRLHNLRELLCGIFPSASQVLAEP
VTRRLMKSVMVEELQQVDLHPSPDLMGSLEQLSEALSRASGIVLLGPAGSGKTTCWHSLF
KIQNRLAAMEKT----STQRYQSVEITHVYPSVLSSQEFLGWLEGSYWHCGVFPRLLRAV
PFCSSMGPQEQTEEDVGTQNWVVCDGAASAAWLDSITCLLSDPPQLSLPNGQQVARRSGT
FLLMEVADATGLSPTLVGRCALVWCSGEQTWQSTFSSLMEVLPHAYRLPPRTVTELSHLA
DGLVPATFRFLTRKGASSLLQAH-GRQAVCPGVAEVSSFGRILRGLLDLHLHLDEKEK--
--------A-------------SKSSSL-YWSKADGNSVPNKDREHLLALSSFLFALIWG
FGAH--------------LPS-RF-WPFFDAFIRNSVGSLSNYPELPPAPLVFELHVSPE
HGTLVPFTGHYLNNYIKGTLGIFCPSA

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2783)

QAERLLYVVELLLSRGQPVLLAGEEATGKSTFV
EVLVEPNHPCIHSPVTPAFHSTHFRLLLSRGVQDQAQA-GSWSARYQDLKDSLLFLLEDL
HLASSDAENSCQPVLETLRQAMDGTMYAPSTLELQNLHPAVNFLATTTVPGGCGRPVCPR
LFRLFTVLALGSMTQATLLSRHTPSIQAWLERFPSVEQVGILGKALVQASVSAWEAMCHC
FMPSPLHPHYRFSLHSVSHLLGSLQLLPTRVGTQVLEDCFFDKEHLYRVSGLRGTYLTIM
MTMRCMLRLWLHEAQRTFCDRLDSPRERAHCANVLLGIAQSVFCHGPGPQHLGKDHEEEE
EEEEEEEEEELVPEVESEGELAQWEDL-----SNS--DTEEEEDLYGLQAPTSSYSSDPS
QVPSI---K--RVSREPRESINH--KAEQGESRRTSSCRLQSTE-STTWWQKAGQ-MDAV
APL--LLPVLLLRPKEKPSDLVFCQELILGSNSEGPN-LYLERQWGSLEEQLATSAAQLR
LSPHLVRSRPMVQHVARLVRVLARPRQHSLLLSGTLGTGRHVAVTLATSVCQARLFHLPA
-GPEEAILQCLRDASWDAGMLSHPVALLVPKSMDLTTLDRLVALATTGSFPDQYTQADLD
SIEEHL-PRENLGIKSNIKKEVLLQRFYQQVCSHLHM-FFLVED--GQASKKLPSTVFLR
LLQLTTTNIDHYESWDQASLVRVAQHHLHGA-ESLPLGDGSFKCPDLQASVPSVAKAMAL
IHLSAAYYHEHLCPVLPLVTPKTFLDFLDTFLLLQQKMIQQIKTRAKMIQNSLENLRVLV
EQHRIHTSLVINLEQQLKDSQKN------------LNLAQQQLEQSKLLYKQQLSECRHQ
ESLTETLVKQRDALQAQHQAFLEQMGKAF

PF12777 // ENSGT00910000144015_1_Domain_7 (3450, 3687)

MGPLSQLKVADFEEIRSYRAPPESVVRVTDA
LCDLFHCETGWASAKQLLCTEDFYQELVFFPKEKMTDAELIKLNHALKAPGMSDTALRTV
SPPAASLVNWLWAVLRYGMAKRRERPTGLLLRQVDAILTREQARLGHYQLQAQEKLEDIL
TWTKKVKDAHAFHSQMLGTLTLAQCGHYKKWPVRPALITPMHTWTTQLQKLRGHCLTVFG
DALVCSAAVVYLGPFPPPRRQELLDKWLALCRGFQ---EPLGPDDVAQALKQKQKP-VIM
PPKTPLLPTRFPFSILSLLSCSSEQHQWDRDLKPQVKSARLAGLLLRSSTHYHSCRWPLL
LDPSNQALMWLSPLPLVEDRCLASAKGKAGVTQQ---------------EASGEDDDNEE
SCEAEEQLQAQKAKEWGK-------------EEEEEKEHEEEEEKNEHEPGSQGFKLALE
TQCPPPLCLSVLSGTDPNL--GPRLWEAAASGQPVLLTNVE--LGLGCPELQQLLQREQL
DPPRVQPGFCLYLSTTLPLDALGK----VLGGELLKGLNVLDLGLNLEILENQTLHEVLY
RECPELEIRWEDLKARALDACEAIEANEEQLLMMLLFQ--NPKHRKPTKFLRDIVRVQAK
ICQMQADYEELKEQKLQEVASWAPYQQVAWHGTAIVKTLSTLQNSLPFFRMSAENWLAAI
RQALDSMKLHDVQHRKDLASHLLQLKAHLTRQLLGRALTALGLTQVPLVGALGAVALLQV
AEEAPKLERLALWPGLAASPSIGPWKSVPGVVRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLTPRTWHECGLLELLPPFVGLRAS
LADHSRVWQDYLSLHSTVLGPAPG--PRFQSLSLLQKLILWRVLRPENLAGALADLTTSL
LGRPLDESLGVPSLPLERSQATQPILILLPPPGHPSVTLHPLTVIQKLAPTNKQ-----H
LQVIALGSEAWNPASDVVSTLHQAMLEGQWLVLDNCHLMS----CWPKELLQPLLGLLDG
AEVVSDPEQALLSAPAESRNVTTVHRDFRLWLIAPAEASASLPAVLSQHSMPVFWDQSLE
LGHVLIHSLELAQQGVHIQG-PTRVLPLLLLHGLLLHRQLYGARLQAHRGRWSHLTLTQA
LETQEQLWASLSNPDTAMQELAASVFYGGPLGDTKDREALISLIQACLRPSSQSWVQPHT
PRYLLATLMPSPELGKLDAITECKAQMHLLPTPLEPGICGLSEGPQAWLLRRRSRTVLHV
LQRSSSVWVPAAVGDA---RRTERRLRQRLVQVKQKLESLQVALNNPSRRDQS---G---
AGRGRSPRRPLEDFLETEALELSQLVGTLQRDLNCQLRQLKGEPPCPSHRCTAIAQALWT
GRLPVPWRPHVPSGLQPPWQWLRQLLCRGQLLVSYLGA--NAGTEVSERVFHLSAFRHPH
RLLLALRWEAALEQ-----HGSSLKSAGSQGPGSC-----HLLHRRRELSSSPLHLQVEN
GPNPKVPEMGL-LLTGLQLLHAVWDPEAGALQDSSSSQPSPLPPVSVSAHTHRARALPRA
AGLAVYFCPVYQAGPLGPAKLHSRSILMHIPLPSKLSVATCIQRRVHVCSPPLP

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--------------------------------------------------------MVPE
EKRVGLSSDETSSDALKSW-HSICVL-DSKEEPLACQQKQRQFVKPATESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTHL
HLDLLGAINQAFPPDSSLLDSASHADCCPQKQRLHHRPPCPACPFVQARWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRKETRSQLDYEVPREKTLQKSSTGFSPETSFLGSQVMTALKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNAEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYCLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCYELLDLQKALAKEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRAGQGSIYLQRVQRKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILEEQITS
FVANILQAPRQKPFLSSQLVFDDHDQLSHVPCVENMIQILTGGLQSVKTSALQVVQSADL
KTSSDSPYSE--EEDEEEDSKTEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVRGYRLRGQYFPCNYKQLEEDLNNNPQIQQALNIQQVLLEGVLWEVQEFCREHHWITGI
YEFLQSWVPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPVELLTKGKLLLLSCRDVQT
EMESKLDSIRKDILAQVQNECWSLSQQLMTELTNFMHVFRTINSDIHAIAQCTQKLNEAN
KQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFRESPIPPRPPPPRPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIIPKLQQLMAAALAELEGLLGKALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSELHHAYVIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTEGWLTEAARMSTTLGLNSPVLQHCMRIL
GEFRSYLPLLAKLGSLQPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIRQLQRYWEVRQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIQKSGDLNKIALEWMAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHAVRFKSCPTG-EKNMDDWES----SPNAQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVAARLARGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLDWGTLAMVSMH
MRKLEVLVNFLRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTTS-SEHSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHSLYAPLYQEASRNTSTID
-------PTEPQLLGSGFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLLKQILEDTIQTLNV
AKEETKCQQPRSLAAIEEAALLHALLHSPLFSVLNGLHLHNLRGLLCALFPSASQVLAEA
MTYKLMKALVVEELQQVGLHPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESMGIQHWIICDGASSAAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADATGMSPTVVGCCALVWCGGEQTWQCILSALMASLPCEYRLQHQTVAELNHMA
EVLVPATLRFLARQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDPHLRLKEEKAP-
--GPEDLSCSDPVAQ---SFRSSKSSFL-NRSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2781)

QTERLLYVVDLLLSGGQPVLLAGEAATGKSVFV
EVLVEPHHPYIYSPIHPAFSSTHLRLLLSRGIQGQTQA-SPQPGHHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERERALARALVRASVEAWEAVCNC
FMPSPLHPHYHFSPHSVSHLLSNLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTRLTIM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQNLVKDHEEDE
------KEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVATGSNSRDPS
LTPST---G--PVSRGMRESISH--KIRQEKGTRASNYRLQVRRSFKTWWQKAPQ-MDLV
SPL--LLPVLLLHPQEKPSDVVFSQELTLGPKSETPN-LYLERQWEKLEEQLATSAAQLK
LSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQTHFFHLPS
-GSEEDILQCLRDASWRAGLLSQPVALLVPSGVDLTTLHRLLALATSGSFPGQYTEADLD
RIEEHF-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSPLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-RSLPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLI
KEHGTHANLISDLEQQLKASSKS------------LSMFQQQLEQSKLLYKQQL

PF12777 // ENSGT00910000144015_1_Domain_7 (3415, 3687)

EECRHQ
ENLIEDLAKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKITDSQLIKLHLILKAPGMSDAALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLIREQARLGYYQFQAQETLENNL
ALAKMVEDAQASHNCVAKTLSQAQRGQYHKWPMKAALLMPMHAWTIQLQKLKGRCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKKPLLATHSPFNILSLLSSASEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALMWLDPLPLAENRCLAPAPTEGRGKGLM----RNQNTESK-MDMKEEDDDSED
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RECPELETRWQNLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNMVRAQGK
LCQLRAHCEELEGQKLQEMVSWAPYRPVVWHGIAMVKALSQLQNLLPLFRMSPEKWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVSGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMGAPTMPFKHSRATQPMLILLPLPGHPTATLHPLTVIQNLAAKYQQ--GQKH
LQVIALGSEVWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLGQPESRNVATVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPRAAMQELAASVFYGGPLEDTEDREALFSLTQACLSPSSRNWVQPHT
PQSLLARLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRVLLSA
LQRSSPVWVPESRGGA---QLAERRLRQRLVQVNRRLESLQDLLTNLVRQDES---GAPR
SVLGPNARRPLEGVLETEALELSRLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGADANSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGAVSS-----PLPYKRLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPPP
ADLTVYSCPVYMGGPLGNTKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

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--------------------LSPL----VLSGDLLKGLSVLDLSQDVDLLEENMLSEIVC
LESPELKTHWQELKTSFLDTCKAVEVAEEKLLVMLLCQ--NTQIPRPDKFLRNMVRIQAE
LCHLRAKKEELEELRMQEMVLWAPYQHVVHHGMALVQALRPLQNLMPLSHLSQIASWATT
TQILSHIKKCEAQPGEDMASHLLQMKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX

PF03028 // ENSGT00910000144015_1_Domain_9 (4226, 5030)

XXXXXXXXXXWLG-LKWHECGMLEMLAPFAGRV--
SAGQSEIWQAYLSLSSTVLGPAPG--PGRDPLSLLQKLILWRVLRPDCLAGALADFTTSV
LGRPLDN-TCAPTMPLAASRATQPMLVLLPPPGHPTATLHPLTVIQKLAATYKQ--GQKH
LQVIALGCEAWDPIPFVVNTLCQAMHKGYWLVLDNCHLMS----HWPQELLQPLLDLFDA
VQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXLKDSIELAQI---CMP-PTQTLPLFFLHGLLLHRQLYGLKLQAHRGRXXXXXXXXX
XXXXXXLWASLSNPRVAMQELAVSVFYGGPVGDIKDRETLISLTGACLSSVSGNWTYPQT
PQHLLATLMPSPELGEQDAIAECKAQMHLLPTPPEPRSCGLSAGPQAWLMRRRSRALLSE
LQRSCGTWVPGVPRVA---QRAERRLRHRLVQVSRRLEALRDLLSEGARQNKL---GAWR
SVLGPTAQSPLEGFLESEVLELKELVSTLQCDLACQLEQLKGAPPCASRRCAAVAQALWA
GRLPPPWRRHAPAGPQPPWHWLRQLSRRGHLLTHYLSGS--ADADVPERTFHLSAFGHPR
RLLLALRWEAALDQ-----YPSGSPGPASQGSSST-----HCVQKRQELTSTPLHFRVEN
GPNPTAPEAGL-LLTGLQVLNAEWDPLAGALQDSSSGQPSPLPPVSVSAQAQGASHLPAP
GGLAVYSCPVYMEGPLGTTRLHSRNILTHMLLPTKLSPATCAQRRVYVCSPPLP

------------------------------------------------------------
-------------------------------RSWNWHLEPELWARSLRQQLNVQLLSPLG
EKRAGL------SLDA---------VLDSTGQSGTYQTKQRKFLMAATDLEQPTVLKLLL
AELQTLFSAVLQDRSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQTQL
QLDLLSAIDHAFPPDSSLLCSASHVDCHPQKKRFHRSPPCPACPFVLAQWGEQQVRQELA
TWLRPLTLPELQHCLGIVGAEVALEETQWLDGLSLLPLALATDIPVQYKSSDTDNVEEEP
IR-----------ISEERPFQKRSSRSSPEVFFSGSQPLNVLNTDKYLKKIYFFYLNVAP
SRYFRYE----PPPPLYSPPHYVFSPFGILHVHPVEGSEVMTLGAWHHQTVLWQQLQLIP
FFKYCLVRKAFTCWRKTMKWQGLCRLRTFLGNHLLLAVPHFGAGLLHINRLLQELHSVSW
LPQEPDQCYELLDLKKALFKENRKALQLLHRCVNLCASIIHLVHEDTYHMQQGLQERVQN
CNRIRAGQGSLYLLKVQRQQLEEKLKQAEAWLLQLGKFARLVNYMICQNLVTILEDEISS
FVANVLQAQRQKPFLSSRLVCGDCCQLASVPNIEHMTEVLSEGLHSIKTSALKLMQSADK
KTLRDSLYLE----DEEDSSDPEFLMPKIQGQPSDAVRIFCGPNVGLVWPWKSHPITGVL
EVRGYRLRGQYLPPNYSQLQENLDNSLRIQQALTVQQALLEGMMQEVQEFCREHHWITDF
CEYLQAWGPPKLEDLRGCPIRKYVMVVSQLGAWQARLSSMPGELLTEGKLLLLSCRETQA
ELESKLDSVKKDILTQVQNECLSRSQQLMTELTDFIQVFQTISTDIXSIAQCSQKLKEAN
EQYLQLEEQVEYIRSLQEFIRSYFNVFTAESEALEIL-----------------------
-------LVDTWETFQLEKTQASEFLLSKQYAIVPKLQQMMATALAELEGLLKKALSGPF
MDPTQEQRSTESKLVSIEHQFKNTASHLCELHHTYVTFTGDESPVPLPVCGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

LQQH
IWHLYRVISETFSEWKCIAFVKFSLPVAQEKTDGWLAEAAQMNAALGVHSPVLQCCIRML
KEFRSYLPLLVKLGSFQRHNLSYQSLLRG-------------------------------
--------GFVRAQENLQRLQQDWESRRLRLLNFILHVPYESSASEHCKKQ---TVSGPQ
WQVVSKDSGTFILSDYNSLQDSIQKSLQVLFKVLAIQKSGDLHKTALEWVTIMQALG---
ALLEVWMAFQQKWIFLNKVLHEMKIQFPSAELHTRFKALDDQYRMLMRISVADPMVLSLI
-MPSAKRSPYFQGQQLQQMLQAGSVELEGIVMALEAVLYGVCAHFPRLFFLSDSELVALL
AASPEPCEAELWAQRCFPHVHTVRFKSNTTN-EKNMDGRE---------CTQVEALAVLG
EGGEEVRLQGPLLLHSDLPKWLASLENCLRLALVCMLQD

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVAARLTVKPSIGETFKK---
LPQQSQLH----LPLNVQHWQCICSREGW--------------------ALGTLATTSRH
IHKLAVLVQFI-----SQGGQPLLSVRQASLLSALLVMAVTHRDIAQLLEKHQVSDLTDF
HWARQLKYHLGPPHLHPQSPLQNLKTVVS-TERSLPPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNFEYLGPRL
GPLPSLLLERPVLILLLALEEVACGTLVGPDGVGKKSMVNSLARALGRQLVMMPCLPQIQ
ARCLSNYLQGALQGGAWLLLVGVHLLPPGLLSALGQCLAELHCLYAPLHLKASQSISTMD
-------PTKPQILGSGLFEKHHVSVRLGYGCLLTLRALSAAVPANLHLLLRPVALAL-P
DLQQVAELTLLGAGVQDAASMATRLSKFFSLERELVSGSLPCRLPLLKQILEETIQTLHV
TKKELESQESGSLAAMEEAALLRALVHSPLFSSLDGFRLHNLRELLCGIFPHASLVLAEP
ISRRLMKSLIIEELQQVDLHPSPDLMGSLEQLSEALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMDKI----SAQRSQPVEITHMYPSVLSSQEFLGWLEGSYWHCGIFPRLLRTA
PHRKRVSPREQTEESTGIQHWVVCDGAPSAVWLDSITCLLSDPPQVSLPNGQQIARPPGT
FFLMEVADTTCMSPTLVGHCALVWCGGEQTWQSMFSVLMASIPREYRLLPHTVIELDQLA
DSLVPATFRFLIRKGASSLLQVH-GHQAVCPGVAEITNLSRILHGLLDAHLGLDEKEM--
--------APDPGGR---DKGG---------TKSKNKDVPNKDREHLLVISSXXXXVIWG
FGAH--------------LPS-RF-WPLFDTFMKNSISSLSNYPGLPPATLVFELHVNPE
DGTLVPFTGQYLSSYIKGSLGIFHP

PF12775 // ENSGT00910000144015_1_Domain_5 (2546, 2782)

STQTERLLYVVDLLLSRGQPVLLAGEEATGKSAFV
EALVEPNHPYIDSRVHPALHSTHFRLLLSRGVQDQTQA-SSRSTCHQDSEGSLLFLLEDL
HLATSDAEKSCQPVLEALRQAMDGTVYAHGTLELQTLQPIVNFLATATVPGGSERPLCPR
LCRLFTVLALGSVTQATLMSRHTPSIQAWLERFPSVEQVGILGKALVQASVDAWEAVCHC
FLPSPLHPHYRFSLHSVSQLLGSLQLLPTRGSSQVFEDYFYDKEHLYRVSGLQGSCLTIM
MSLRYVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLEVAQRVFCHGPGPQLLVRDYEGEE
------EEEENVPEVESEGELAQWEDL-----SNSNSETEEEEDPYGLQATTSSFSSDPS
VAPSI---K--RVSRETTESISH--KTEQREGKRASSCKLQSKE-FNT-LQKATQ-VDMV
APL--LLPVLLLRPKEKPSDLVFCQELTLGSSSEGPN-LYLERQWGRLEKQLATLAAQLR
LSPHLVQGRPMAQHVARLVRVLARPQQHGLLLSGAPATGRRVAVTLAASVCQARLFHLPT
-GPEEAILQCLRDASWDAGILSHPVALLVPKTVNLTTLYRLVALATVGSFPDQYTEADLD
NIEAHF-PRDNLVNKYNIKKEM--------------------------------------
-------------------------YHLEGA-QSLPLDDGKSPFHP--------------
--------------------P---------------------------------------
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-----------------SLLMRVIMGKAFLGP

PF12777 // ENSGT00910000144015_1_Domain_7 (3453, 3687)

LSQLKVTDFEEIRSYRAPPESVVRVTDT
LCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKMTDTELIKLNDALKSLGMNDRALRAV
SVPAANLAAWLWAVLRYGLAQRRGLPTGLLLRQVDEILTREQARLGHYQLQAQEKLEDIL
TLTKKVQEAYVTYNHMLGALAIAQRGHYKKWPVKPALITPMHTWTTELQNLSGHSMTVFG
DALVCSAAIVYLGPFPPPRRLELLDK

ENSGT00910000144015_1_Linker_7_8 (3687, 3774)

WLALCRGFQ---EPLGPDDVAQALKQKQKP-IIM
PPKNPLLPTRFPFSVLSLLSCSSEQHQWDRDLKPQVKSARLAGLLLRSCTHYH

PF12781 // ENSGT00910000144015_1_Domain_8 (3774, 4061)

SCRWPLL
LDPSNQALNWLSPLPLEENRLLMSAPTDGRVYLAL---------L---------------
----ETL--------------LTTQ-----KEEEQEGEEEEEKEMKENELESQGSKVALE
TQSSPLLCLTVLSGTDPKL--GAQLCEAAANGQPVLLTNVE--LGLGCQELQWLLHREQL
MPPHVQPGFCLYLSTTLPLHALQK----VLGCELLKGLNVLDLGLNLEILEDQMLHEVMH
RECPELEIRWENLKTSTLDACGAIEAAEEKLLTMLLSKDE

ENSGT00910000144015_1_Linker_8_10 (4061, 4397)

NSKDEKPAKFLRHIVRIQAK
ICQMQTYCEELKEQKLQEVVLWVPYQQVVWQGIAIVKALSTLQNSLPFFHMTAENWLAVT
RQALDSMKPRDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXPGLPASPSTGYQKSDPSVVRPAWLTPRVWHECGTLELLPPFAGLRAS
LADHSSVWQDYLSLNSTVLGPAPG--PTSEPL----------------------------
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----TLGSEAWNPVSD

PF03028 // ENSGT00910000144015_1_Domain_10 (4397, 4543)

VVSTLHQAMLEGHWLVLDNCHLMS----HWPRELLQPLLGLLDG
AKVVSDTEVPLLLAEVESRNVVTVHRDFRLWLIASAEASASLPAVLSQHSMPVFWDQSLE
LGHTLIHSLELAQQEVHMQS-PTQALPLLLLHGLLLHRQLYG

ENSGT00910000144015_1_Linker_10_9 (4543, 4582)

MRLQAHRGRVL-------
------------------TSS

PF03028 // ENSGT00910000144015_1_Domain_9 (4582, 5029)

SASVFYGGSLGDIKDREALTSLTQACLRPSSQSRVQPHT
PRYLLATLMPSPELGKLDAIAECEAQMHLLHTPSEPGICGLSEGPQAWLLRHRSRALLSV
LRRSSSSWVPAARTGS---RRTERRLRQRIVQVQQNLESLQAALNNHTRRDQA---F---
ALRGRGTRRPLEDFLKTEALELSQLVGTLQRDLDCQLRQLQGEPPCPSHRCMAVAHALWS
GRLPVPWRPHAPSGPQPPWQWLRQLSCRGQLLVSYLGA--NTGTEVSERIFHLSAFRHPR
RLLLALRWEAALEQ-----RVSSSKFPGSQGPSSR-----HLPNKRRELSSGPLHLQVEN
GPSPKVPEMGL-LLIGLQLLHAKWDPVAGAVQDSSSSQPSPLPPVSVSAGTHRASAGPRA
AGLVVYSCPVYLAGPLGTAKLHSRNILMHIPLPTKLSLATCIQRRVHVCSPPLP

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--------------------------------------------------------LVSK
ERRVGLSSGEASSDALESG-HSVHVL-DSIEQPGACQRKQRQFLKPVTESEHPTVLELLL
AELRTLFSAVLQDGSPAAWRYLHAVLGLLPPYRELLVGYLDLLPLLEQLYCWAPRVQTQL
QLDLLEAMDQAFPPDNSLLDSASHIDCRPRKQRFHHGPPCPACPFVQARWGAQQVQEELA
TWLRPLTLPELQRCLGIVGAEMALEEALWLDGLSLLPLALATDIPVQYESSDTDNIEKEP
VGRRGTRSQLDYEVPGEKAFQRRSTGFLPDISSLGSQMMTILKTEGYLNKIHFLYLNVAP
NRYFRPYDLVVVPPNKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHRHSVLWQQLQCIP
FFKYCLLRKSLTCWKKNVRLQRLHRLRTFLGSHLLFAVPHFGAGLLQISRILQELRSVSW
LPQELDRCYELLDLQKALAKEKHKALRLFHRCLNLCTSILQLVHEDTYHMQQGLQERVQN
CNRIRTGQGSIYLQRVQRQQLEQKLKQAEAWLLQLGKLARLVDYMICQSLVSILEEEITS
FVANILQAPRQKPFLSSQLNFDDCGQLSHVPCVENMIQILTGGLRSVKASALQVIQSADL
KISWDSLYSE--EEDEEEDLNTEFPMPKFQGQPSDAVRIFCGPNVGLVWPWKSYPIAGLL
EVRGYRLRGQYLPRNSEQLQEDLDNNSRIQQALTIQQVLMEGMLREVQEFCREHNWLTTI
YEFLQSWGPQKLEDMRGCPIKNYVRLVSLLNNWQARVSNMPIKLLTKDKLLLLSCHNVQA
EMESKLDKMKKDILAQVQNECWSRSKQLMTELTDFTLVFQTINSDIHAIAQCSQKLDEAN
EQYIHLEKRVEYIRSLHELIRNHCNLLSAENEALDISVRGQFRESPIPPSPPPAQPQGLH
YPLLAPQLLDVWEAFQFEKSQASEFLLSKQHSIVPKLQQMIAAALAELEGLLEKALSGPF
MDPTQEQRSTECQLISMERQFQNTVSHISELHRAYATFTGDESPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1600)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTDGWLTEAARMCVTLGLHSPVLQCCMHTL
EEFRSYLPLLTKLGSLRLQNLNCQSLLRALGLGCLRNIELLTLGQLLTCPLLEFADR--I
NQVWQYENDRIHAQESLQKLQQCWEVRQLRLLNFILHVPYEPPVSERSKRH---MLCSPQ
WEVVGKDSGTFILSDYSSLQDSIQESLQVLFKIMAIQKSGDLYKTSLEWVTIMHGLG---
ALLEVWVTFQQKWIFLNKALHEMKIQFPSADLNSRFKAMDDQYRTLMRISVADPMVLSLI
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMALESVLYGVCAYFPRLFFLSDSELVALL
AAPLESCEAKLWVQRCFPHVHAVNFKSCSTD-EKNRDDQAS----SPSTQTQVEALAVLG
VGGEVVELQEPLPLHPDLPKWLASLEQCLRLALVHMLQN

ENSGT00910000144015_1_Linker_1_3 (1600, 1791)

CVAARLAQGPSLGEAFKQ---
----SQLP----PQLYGYHWLDLVEAFPWQCVLVAEEVVWRAEMEETLLKGGTPAMVPMH
TRKLEVLVYFVRAQRGSQGGQPLPSVRQASLLSALLVMAMTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHMIPQSPLQSLKAIAS-TEPSLAPAACWVDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERTALVLLLALEEVACGTLLGPDGVGKVATVKNLARALGRQLVMMPWSSQIE
AQCLSNYLNGALQGGAWLLLDAAQHLPSGLLSALGQRLAEVHHLYAPLYQEASRTTSTTD
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLTLRALSPAVPANLHLLLRPVALAL-P
DLQQVAELTLLGAGIRDASRMATRLSKFFFLERELVSGPLPCRLPLLKQILQDTIQTLNE
TKGEPKTQQPRSQAALEEAALLRALLRSPLFSILSGLRLHNLRELLCGLFPSASQVLAEP
MTHRLLKPLMVEELRQVGLHPSPDILGSLEQLSQALCRTSGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEAT----STHGYQPAEITHLYPSVLSPQEFLGWLEGPCWHHGVFPRVLHAA
SQCNSMGPKGQKEESVGIQHWIICDGASNAAWLDFITCLLSELPQLTLPNGQQIARPPGT
FLLMEVADATGMSPTVVGCCALVWCGGEQTWQCMLSVLMASLPHEYRLQQQTITELNRLA
EVLVPATFRFLARQGASSVLQVH-GQQAVCPGVAEVTSLARILRALLDPHLHLEEKKAR-
--GPEDLSVSDPVSQ---SIKSSKSGSL-NQSQADSNDVSNKHREHLLAVSSFLFALIWG
FGAH--------------LPS-RL-WPVFDTFMRGSISCLSNYPEPPPSALVFDLHVSPE
DGTLAPFTGHYLSNHVKGTLGTFHP

PF12775 // ENSGT00910000144015_1_Domain_5 (2546, 2782)

STQTERLFYAVDLLLSAGQPVLLAGEAATGKSAFV
EVLVEPSHPYIYSAIHPVFSSTHLRLLLSRGVQGQAQA-SLWSGHHQDSKDSLLFLLEDL
HLATSDPEKSCQPVLETLRQAIDGTVYAHGTLELQTLQPIVNFLATATVPGYCERPLCPR
LFRLFTVLALESMSQATLLSRHVPGIQAWLEGFPSVEQESVLARALVRASVEAWEAVSNC
FMPSPLCPHYRFSLHSVSQLLGSLQLLPTRIGSQGFVDCPNHQEHLRRVSGLRGTRLTIM
VAMRNMVRLWLHEAQRTFCDRLDSPKERSYCAKLLLEVAQSVFCCGLGPHQLGEDLEEDE
-------EEEKVSEVESEGELAQWEDS-----SNSNSETEEEEDPYGLQIIRSSHPTDSS
RAPSI---R--PASRETTESISH--KIRQEEDTRAPSHQLQGNKSSKSWWHKAPQ-MDQI
SPL--LLPALLLRPQEKPSDLVFSQELILGSNSESPN-LYLERQWESLEEQLATSASQLK
LSPNLARCHSMAQHVARLVRVLARPRQHGLLLSQALGTGRHTAITLASGICQARLFHLPS
-GSEEAILQCLRDASWHAGMLGQPVALLVPKRVDLITLHRLLALATSGSFPDQYTEADLA
NIEKHL-PRENTGAKQNIRKETVLQRFYQQVCSHLHM-FFLIED--EQAHKQMPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLESA-QSLPLDDGSWKCPDLQASIPSVAKAMAR
IHLSAAYYHEQLCPVLPLVTPKTFLDFLDTFLLLQQQMTLQMKNKALRIQNAMENLRMLI
EEHNAHANLVFNLEQKLTDSRKN------------LSIFQQQLGQSKHQYRRQLAECRHQ
ENLIENLAKQRDALQDQHEAFL

PF12777 // ENSGT00910000144015_1_Domain_7 (3443, 3687)

EQMGKAFLGPLSQLQVADFEEIRSYRAPPESVVQVTDA
LCNLFHRETGWASAKQLLCTEDFYQKLVFFPKEKMTDSELTKLHLALKAPGMSNAALQAV
SASAASLVTWLWAVLHYGLAQRRGLPTGLLLQQVEVTLAREQARLGHYQFQAQELLEQNS
ALTKKVEDAQASYNSVEEALNWTLCGQYHKWPIKAALLTPMHSWTTQLQKLKEHYITVFG
DALLHSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSMP
-PKKPLLPTCSPFSILSLMSSASEQCQWDRDLKPQAKSARLAGLLLRSTTHYSRCRWPLL
LDPSNQALMWLSPLPLTENRCVVPA---GRGKGLM----RNQNRKSKEEDTKEEDDDSEE
SHEAKDQTKEQKAEERENKEEENKK-----EQE-QEEKKEQEEKEKEKETESQRSKPASE
TQSPPLPCLRVLSGADPEL--GPQLWEAAAGGLPVLLTNVE--LGLECQELQWLLQREQL
SPPQVQPGFCLYLSTTLPLHALEK----VLGCELLKGLNVLDLGLNMEILEEQMLHEILC
RERPELETRWQELKIRAMDAREAVEAAEEQLLMRLLLQ--NPKCQKPAKFLRNMVRAQAE
LCQLRAHSEEVEEQKLQEMVLWAPYRRVAWHGMAIVKALSQLQNLLPLFRMSPENWLAAT
KQALDRMKPCEIRHGEDLASHLLQLRTHLTHQLLGSAVAALGLTQLPLVGALGALALLRV
TRKASELERLAFWPGLAASPSTSHSKEVPSVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWVGPRAWRECELLELLPPFVGLCES
LAGHSNVWQAYLSLSSTVLGPAPG--PGSKPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENLGAPTMPFKHSQATQPMLILLPPPGHPTATLHPLTVIQKLAAKHEQ--GQKH
LQVIALGSEAWDPVSVVVSTLCQAMNKGHWLVLDNCHLMP----HWPKELLQPLLGLLDG
AKVVSDVELELLLAQPQSRNVATVHRDFRLWLIVSVESTASLPAVLTQHSMPVFWDQSLE
LGHVLIDSVELAQQGLYMQS-PTQALPLLLLHGLLLHRQLYRTRLQAHRGRWSQVTLTQV
LKIQDQLWASLSNPSAAMQELAASVFYGGPVGDTEDRKVLISLTRACLRPSSGSWVQPHT
PQYLLATLMPSPELGELDAMAECKAQMHLLPTPSEPRICGLSEGPQAWLLRRQSRALLSA
LQLSSPTWVPVARGST---QRAERRLRQRLMQATRRLESLQILLTDTAR-QEF---SAPW
AVLGPNARRPLEGFLEVEALELSQLAGMIQQDLDCLLQQLKGAPPCASQRCAAVAHALWN
GRLPQPWQAHAPAGPQPPWHWLRQLSRRGQLLVRYLGVGVD--TDVPERVFHLSAFRHPR
RLLLALRWEAALNQ-----NVSSSNFPGSQRSGSS-----QFPHKRQELNSSPLHLQVEN
GPNPSVPERGL-LLIGLQLLHAEWDPIAGALQDSPSSRPSPLPPVSVSTQAPDATDLPTP
AGLTVYSCPVYMAGPLGTTKLQSRNILMHLPLLTKLSPATCVQRRVHVCSPPLT

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PF08393 // ENSGT00910000144015_1_Domain_1 (1419, 1603)

IDDQYRTLMQISVADPLVLSLI
-VPSAKRSPHFQGQQLQQLLQKGSVELEGMIMALESVLYGVRAHFPRLFFLSDSELVALL
AAPLESYEAQLWVRRCFPHVHAVSFKSSPTG-KNMVDDRES----SPSTQTQVEGLSVLG
AGGEEVKLQGSLPLHPDLPKWLASLEKCLRLALVHMLQDCVAARLALGPSLDKAFTQ---
LPQQSQLS----LQSYVHHWLDLVQAFPWQCVLVAEEVVWRAKMEEALLEERTLAMVNMQ
VRKLEVLVHFVRAQRASKGGQPLPSVRQTSLLSALLVMAVTHRDIAQLLQKHQVSDLMDF
HWARQLKYHLGSSHTPPQSPLQSLKTSAS-TETSLSPAACWIDVLGRSFLYNYEYLGPRL
GSLPSLLPERPALVLLLALEEVACGTLLGPDGVGKAAMVQSLAQALGRQLVVMPCLPQIE
AQSLSNYLNGALQGGAWLLLQAAQHLPVGLLSALGQRLAELHHLYAPLYQEASRNTSTVD
-------PTHFQLLGSGFFEKHHVSMRLGYGCLLTLRALSPAVPANLHLLLRPVALTL-P
DLQQVAELTLLGAGMRDASHIATRLSKFFSLERELVPGPLPCRLPVLKQVLEDMIQALNV
TKEEPKSQKPHSLAAIEEAALVHALLRSPLFSILNGVHLHNLRELLCGLFPSATQVLAEP
MTHRLRKPLLVEELRQAGLHPSPDILGSLEQLSQALGRASGILLLGPAGSGKTTCWQSLF
KIQNRLAVMEDA----STQGSQHVEITHLYPSVLSPQEFLGWLEGSYWHHGIFPRLLRAA
SQSKTVGPKGQAQESVGIQHWIICDGASSAAWLDSITCLLGEPPQLSLPNGQQIKRPPDT
FLLMEVGDATGMSPTVVGRCALVWCGGEQTWQGMLSVLMAALPHEYRLRLQTVIELNRLA
EVLVPATFRFLISQGASSLLQVH-GQQAVCPGVAEVTSLARILRCLLDPHLHIDEEETAH
--IPEDLSSNDPVAQ---SLKSSKSSSL-NRSQVDSDDVPIKHREHLLAISSFLFALIWG
FGAH--------------LPS-RY-L----------------------------------
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-------------------------------------------------------LLASE
-PKRGSSPEEALSEDLES-QHSIYVP-DEEKQPWDGQRKQRQFLKAVTQSQQPTVLELLV
AELQNLFSAVLKDGSPAAWHYLHAVLRLLPPYRALLVGRLDLLPFLEQLSHWAPWVQSQL
QLDLLDAIEQAFPPDTSLLESASHIECCPQKQKFHHGPPHPACPFVQARWGGQQVGEELA
TWLRPLTLPELQHSLGIVGAQVALTETWWVDGLSLLPLALATDIPVQYESQGTDNTAEEP
VGRKETKSQLDPEVPGKKTFQKRSTVFSLQTSLLGSQVMTILKTERYLKKIHFLYLNVAP
SRYFRPYNLVVVPPKKVNPEHYIFSPFGILHIHPVEGSETITLGTWHRHSVLWQQLQFIP
FFKYCLLYKALARWKRSVKLQGLQRCRTFLEKHLLLAVPHFGAGLLHISRLLQELRSVPW
LPQEPNRSYKLLDLQRALAKENHKALRLLHRCLHLCTSIFQLVHEDTYHMQQGLQERVKN
CKRIRTDQRSVYLQRVQCQQLEQKLKQAESWLLRLGHLARLVDYMICQSLVSIIEEEITS
FVANILQAPRQKPFLSAQLVFDNCGQLSHEPCIENMIQILTGGLQSVKASVLKVMQSTDL
KTPWDSLY--SEGEGEEEEGNTEFVMPKLQGQPSEAVHIFCGPNIGLVWPWKSHTVTQAL
EVRGYQLGGQFLPFNFKQLQEDLDNSPRIQQALTMQQTLLEGMLREVKEFCREHHWMTGI
HEFLQAWGPQKLESMRGCPIKNYVMLVSCLNVWQTRVSNIPNKLVTKGRLMLLSCHHVQL
EMESKLDSIRRDILTHVQNECRTRSQQLITELRDFTEVFQGINSDIDAIARCSQKLNEAN
EQYNMLEERMEYIQSLHEVIRNHFSLFSDENEALDISVRRQFLKSPMP-PPPP-RCSLLD
CTLLAPQLLDVWEAFQFEKSQASEFLLSKRYAIVPKLQQLIAAALVELEGLIDKALSGPF
MDPTQEQRSTERQLISLERQFQNTASHLSELHHAYATFTGDESPVPLPVCGTRP

PF08393 // ENSGT00910000144015_1_Domain_0 (1135, 1294)

IVQQQR
IWHLYRVISENISEWKCMAFAKFSMTMAQEKTDGWLTEAARMSTTLGLHSPVLQHCMRML
EEFRSYLPLLTKLGSLQLQ--NFQALLQALGLGSLHNMELLTLGQLLSCPLLEFADR--I
NQIWQCENERVHAQEILRQLQQGWETRQLRLIN

ENSGT00910000144015_1_Linker_0_1 (1294, 1326)

FILHVPYEPPASEHSKKH---EVRSPQ
WEVVS

PF08393 // ENSGT00910000144015_1_Domain_1 (1326, 1602)

QDSGTFVLSDYSSLQDSIQESLQMLFKILAIQKSGDLNKIALEWVTIMHSLS---
ALLKVWVIFQQKWIFLNKVLHEMKIEFPNPDLNSRFKAMDDQYRTLMLISVGDPLVLSLI
-VPSVKRSPHFQGQQLQQLLQAGSVELEGIIMALKSVLYRVCTHFPRLFFLSDSELVALL
ASPLESCEAQLWVRRCFPHVHAVSFKSSPTD-RN-TGDRES----SPNTSTQMEAVAVLG
AGGEEVKLPVSIPLHPDLPKWLAFLENCLRSALVHMLQDCV

ENSGT00910000144015_1_Linker_1_3 (1602, 1791)

ASRLALGPSLDETFKQ---
LPQKGQLP----PQLYVHHWLDLVQAFPWQCVLVAEEVVWWAEMEEALLEGRTLAMVPMH
VCKLEALVHFIRAQRASQGEQSLPSVRQTSLLSALLVMAVTHRDIAQLLQEHQVSDLRDF
HWARQLKYHLGSPDAIPQSPLQSLKTIAS-TETSPSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GSLPSLLPERPALVLLLALEEVACGTLLGPDGVGKAAMVKSLAQALGRQLVMMPCLPQIE
AQCLSNYLNGALQGGAWLLLEAAQRLPLGLLSALGQRLAELQHLYAPLYQEASRSTSTVD
-------PTQPQVLGSGLFEKHHVYIRLGYGSLLTLRSLSPAVPANLHLLLRPVALTL-P
DLQQVAELTLLGAGMRDASRMASRLSKFFSLERELVAAPLPCRLPLLKQVLEDMIQDLNA
TKDES-----KSLAVIEEAALLRALLRSPLFSILKGTHLHNLQELLCGLFPNARQVLAEP
VAHTLKKPLLLEELQQIGLHPSPEILGSLEQLSQALG----VLLLGPAGSGKTTCWHSLF
KIQNRLAAREDT----STQGCQPVEISHLYPNVLSPQEFLGWLEGPCWHHGIFPRLLRTA
SPCQTVGPKEPPQESGGIQHWIICDGVASAAWMDSITCLLGEVPQLSLPNGQQIARPPGT
FLLMEVGDVTGMSPAVVGQCALVWCGGEQTWKDMLSVLMAALPHEYHLQLQTVTELNHLA
EVLVPATFGFLTHQGASSLLQVH-GQQAICPGVAEVTSLARVLRCLLDPHLRIDEKEKAH
--ISEDLSFSDPMAQ---SCKSSKSSSL-NLPQVDSDDVPNQRKEHLLAVSSFLFALIWG
FGAH--------------LPS-RL-WPLFDTFLRDSISCLSDYPEPPSSALVFDLHVCPE
TGTLVPFTGHYLGSRIRGTLGTFSPSP

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2782)

QTERLLYVVDLLLSEGHPVMLAGEAATGKSTFV
EMLVEPHHSYTCSPIHSAFTPLHLRLLLSQGVQGQPQA-APRPGQHPDSKGSLLFLLEDL
HLAASDPQKSCQPVLETLRQAIDGTVYAHHTLELQTLQPTVNFLATATVPGFCERPLCPR
LFRLFTVLALGSMTQAMLLSRHTPSIQAWLERFPSVEREGVLAKALVRASVEAWEAVHNC
FLPSPLHPHYRFSLHSVSQLLGSLQLLPTRMGSRGFLDCPNHQEHLRRVSGLRGTRLTIM
MAMRNMVRLWLHEAQRTFCDRLDSPRERSYCANLLLEVAQSVFCCRPAPQNRGKGYEEED
E----EEEEEKVPEVESEGELAQWEDL-----SNSGSETEEEEDPYGLQVTTGSPSNDPG
LAPSI---A--PVKRETTEG------INQEEDTKSSGYKLQLNR-NKNWWQKTSQ-IDLA
SPL--LLPVLLLRPQEKPSDLVFSQELILGSNSESPS-LYLERQWESLEEQLSTAAAQLK
LSAHLARCHSMAEHVARLVRVLARPRQHGLLLSRALGTGRHTAITLAASIYQARLFHLPS
-GSEEAILQCLRDASWHAGMLGQPVALLVPKGVDITTLHRLLALATSGSFPDQYTEADLD
SIEEHL-PRENLSVKQNIKKEMLLQRFYQQVCNHLHM-FILIGD--DQAHKQLPSTLFLR
LLQLAIASIDRYEPWDQDSLISVVQHYLESD-HNLSVDGDSLKYPDLQASVPSVAKAMAL
IHLSAASYHGHLCPELPLVTPKTFLDFLDTFMLLQQQMTLQIKNKAQRIQNALDNLRMLI
EKHNAYTNFVFNLEQLLKGSHKN------------LRILQQQLDKGKLLFRQQLAECQQQ
ENLIENLTKQRDALRDQYEAFLEQMGK

PF12777 // ENSGT00910000144015_1_Domain_7 (3448, 3687)

AFLGPLSQLQVADFEEIRSYRAPPESVVQVTDA
LCDLFHCETGWASAKQLLCSEDFYQELVFFPKEKMTDSEMIKLTQALKAPGMTDAALRAV
SVPAARLAAWLWAVLRYGLAQRRGLPTGLLLRQIEATLAREQTRLGHYQFQAQEIIEHNL
DLAKKLEDTQTSHNHLMEKLSQAQCDQYRKWPIKAALLTPMHSWTTELQKLKGHCATVSG
DALLCSAAIVYLGPFPPLRRQELLDKWLALCRGSQ---EPLNPDDVAQVLKQKQRSVVMP
-PKNPLLSTRSPFSLLSLLSSGSEQCQWDRDLKPQAKSARLAGLLLRSRTHYSSCRWPLL
LDPSNQALIWLNPLPLQETRCLAPGPTECRATGES----FVRNQEKEEAMEEDDDDSSEE
SNEAEDKAKEQK-TEDKANEDEEGKKEQE------------QEHKEEEETEREESRPASE
TGSLPLPCLHVLSGTDPEL--GPQLQEAAASGLPVLLTNVE--LGLGCQELQWLLRREKL
SAPEVQPGFCLYLSTTLPLSALGKDDPQVLGYEVLKGLNVLDLSLNMDILEEQMLHEILC
IECPELKNRWQDLKTRILDSCEAVEAAEERLLL-LLLQ--NPNHQKPAKFLRGLVRAQAE
LCQLRAHSEDLEDMRLQEVALWVPYRRVVWHGMAIIKALSPLQNLLPPFRMSPDNWLAAT
KRALNSMKQHETHQGEDLPSHLLHLRKQLTRQLLGSAVAALGLTQVPLVGALGALALLQV
TRKAPELERLAFWPGLAASPSTGCSKP--GVA

PF03028 // ENSGT00910000144015_1_Domain_9 (4233, 4993)

RPAWLGLRAWHECRMLELLPPFAGLCAS
LASHSSVWKTYLSLSSTVLGPAPG--PGPDPLSLFQKLVLWRVLRPECLARALADFTTSL
LGRPLDGNLGASSIPFEHSQATQPMLILLPPPGHPTATLHPLTVLQRLAAKHEQ--GQKH
LEVIALGSEAWDPVSVVVSTLCQAMHKGHWLVLENCHLMP----HWPKELLQPLLGLLDG
ARVVSDLELELLPAQLASRSVTTVHRDFRLWLILSAEAVGSIPAVLTHHSMPVFWDQSLE
LGHVLIDSLELAQQGLSVQP-PTRTLPLLLLHGLLLHRQLYGMKLQAHRGRWSQVTLTQV
LQIQDQLWASLSNPSVAMQELAASVFYGGPVGDKKDREALISLTRACLDPSNRSRAHPHT
PQYLLSTLLPSPELGELDALAECKAQMHLLPTPPEPQSCGLSAGPEAWLLRRRSHALWSA
LQRTSPAWVPAPRGGA---RRADRRLRQRLAQAKRRLEALQAVLTETARRKES---AAGR
AVLGLSSRLPVQAFLQAEVLGLSRLAGALLRDLGCLARQLKGAPPCASPRCAAVAHALGT
GRLPPPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVD----ARVPERIFHLSAFGHPR
RLLLSLRWEATLATAARNQRAPSSNVPACQGSSSN-----ELPAKRPELNSSPLHLQVVN
GPNPTVPEMGL-LLIGLQLRNAEWDPLTGALQDSTSSQPSPLPPVSVSAQVRGPSDLAPP
AGLAVYSCPVYMEGALGITRLHSRNILMHLPLPTKLSPATCDQRRVHVCSPPLL

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--------------------------------------------------------MVPE
EKRVGLSSDETSSDALKSW-HSLCVL-DSKEEPLACQQKQRQFVKPATESEQPTVLELLL
AELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDFLPFLEQLYCWAPWVQTHL
HLDLLGAINQAFPPDSSLLDSASHADCCPQKQRLHHRPPCPACPFVQARWSRQQVKEELA
TWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALATDIPVQYESSDTDNAEEEP
VGRKETRSQLDYEVPREKTLQKSGTGFSPETSFLGSQVMTTLKTERYLKKIHFLYLNVAP
SRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQFIP
FFKYYLLRKSFTCWKKNVRLQGLHRLRNFLENHLLLAVPHFGAGLLHISRLLQELHSVSW
LPQELDRCCELLDLQKALAKEKHKALRLLHHCLNLCTSILRLVHEDTYHMQQGLQERVQN
CDRIRAGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISILQEQITS
FVANILQAPRQKPFLSSQLVFDDHDQLSHVPRVENMIQILTGGLQSVKTSALQVVQSADL
KTSSDSLYSE--EEDEEEDSKTEFLMPKFQGQPSDAVSIFCGPNVGLVWPWKSHPIAGIL
EVHGYRLRGQYFPRNYKQLEEDLNNNPQIQQALNIQQVLLEGVLWEVQEFCGEHHWITGI
YEFLQSWVPQKLEDMRGGPIKNYVTLVSRLNVWQARVSSMPIELLTKGKLLLLSCRDVQT
EMESKLDSIRKDILAQVQNECWSLSQKLMTELTDFMHVFRTINSDIHAIAQCTQKLNEAN
EQYVELEERMEYVRALHELIRNHFSLFSAENEALDISVRRQFGKSPIPPRPPPPRPHLLH
CPLLAPQLLDMWEAFQFEKSQASEFLLSKRHAIIPKLQQLMAAALAELEGLLGKALSGPF
MDPTQDQRSTEHQLISLERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIV

PF08393 // ENSGT00910000144015_1_Domain_1 (1137, 1598)

QQQR
IWHLYRVISENISEWKCMAFAKFSLAMAQEKTEGWLTEAARMSTTLGLNSPVLQHCMRIL
GEFRSYLPLLAKLGSLQPQNLNSQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR--I
NQVWQNENERIHAQETIRQLQRYWEVRQLRLLNFILHVPYEPPASERSKRQ---VLRSPQ
WEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIQKSGDLNKIALEWMAIMHGLG---
ALLEVWLTFQQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLV
-VPSAKRSPYFQGQQLQQLLQAGSVELEGIIMTLESVLYGVCAHFPRLFFLSDSELVALL
AARLESCEAQLWVRRCFPHVHGVRFKSCPTG-EKNMDDWES----SPNAQTQVEALAVLG
AGGEEVKLQGPLPLHPDLPKWLASLEKCLRLALVHML

ENSGT00910000144015_1_Linker_1_3 (1598, 1791)

QGCVTARLAQGPSLGEALKQ---
LPKQNKLY----LQLYVQHWIDLVQTFPWQCVLVAEEVVWRAEMEEALLEWGTLAMVSVH
MRKLEVLVNFMRAQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDF
HWVRQLKYHLGSPHIIPKSPLQSLKTTAS-SEHSLSPAACWIDVLGRSFL

PF12774 // ENSGT00910000144015_1_Domain_3 (1791, 2017)

YNYEYLGPRL
GPLPSLLPERPALVLLLALEEVACGTLLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIE
AQCLSNYLNGALQGGAWLLLEKVQQLPPGLLSALGQRLGELHRLYAPLYQEASRNTSTID
-------PTQPQLLGSGFFEKHHVSMRLGYGCLLVLRALSSAVPANLHLLLRPVALAL-P
DLRQVAELTLLGAGMRDAFQMATRLSKFFSLEHELVSGPLPCRLPLLKQILEDTIQTLNV
TKEEPKCQQPRSLAAIEEAALLHALLRSPLFSVLSGLHLHNLRGLLCVLFPSASQVLAEA
MSYKLMRALVVEELQQVGLHPSPDILRSLEQLSQALSRASGILLLGPAGSGKTTCWHSLF
KIQNRLAAMEDT----STQGCQPVEITHLYPSGLSPQEFLGWLEGSCWHHGIFPKVLRAA
GQCNNMGQKRQTEESMGIQHWIICDGASSSAWLDSITCLLSELPQLSLPSGQQIARPPGT
FLLMEVADATGMSPTVVGCCAVVWCGGEQTWQCILSALMASLPYEYRLQHQTVAELNHMA
EVLVPATFRFLARQGVSSLLQVH-GQQAVCAGVAEVTSMARILHSLLDAHLRLKEEKAP-
--GPEDLSCSDPVAQ---SFRSSKSSFL-NQSQVDSDDVPNKCREHLLAVSSFLFALIWG
FGAH--------------LPS-RF-WPVFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE
DGTLVPFTGQYLSSHIKGTLGTFHPSI

PF12775 // ENSGT00910000144015_1_Domain_5 (2548, 2782)

QTERLLYVVDLLLSRGQPVLLAGEAATGKSVFV
EVLVEPHHPYIYSPIHPALSSTHLRLLLSRGIQGQTQA-SPPPGHHQDSKASLLFLLEDL
HLATSDPEKSCQPVLETLRQAMDGTVYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPR
LFRLFTVLALESMTQATLLDRHVPIIQAWLERFPSVERECALARALVRASVEAWEAVCNC
FMPSPLHPHYHFSLHSVSHLLSNLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTRLTIM
MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVFCCGPGPQNLGKDHEEDE
------EEEERVPEVESEGELAQWEDF-----SNSNSETEEEEEPYGLQVATSSNSSDPS
LTPSI---G--PVSRGMRESISH--KIRQEKGTRASNYRLQVRRSFKTRWQKAPQ-MDLV
SPL--LLPVLLLHPQEKPSDVVFSQELTLGPNSETPN-LYLERQWEKLEEQLATSAAQLK
LSSHLAQCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPS
-GSEEAILQCLRDASWHAGLLSQPVALLVPSGVDLTTLHRLLALATSGSFPGEYTEADLD
RIEEHF-PRENLGVKQNIKKEMVLQRFHQQVCSHLHL-FFLIGD--KQAHKQLPSTLFLR
LLQLATASIDRYEPWDQAALVKVAQHHLEGA-RSLPLDDGSWKYPDLQASIPSVAKAMAL
IHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLI
KEHGTHANLISDLEQQLKASSKS------------LSMFQQQLEQSKLLYKQQLEE

PF12777 // ENSGT00910000144015_1_Domain_7 (3417, 3687)

CRHQ
ENLIENLAKQRDALQAQQEAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDA
MCDLFHRETGWASAKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMSDVALRAV
SRPAASLAAWLWAVLHYGLAHCRGLPTGLLLQQVEATLIREQARLGYYQFQAQETLENNL
ALAKMVEDAQASHNCVAKTLNQAQRGQYHKWPMKAALLMPMHAWTIQLQKLKGRCMTVFG
DALLCSAAIIYLGPFPPLRRQELLDKWLALCRGFQ---EALGPDDVAQALKQKQKSVSIP
-PKNPLLATHSPFSILSLLSSASEQYQWDRNLKPQAKSAHLAGLLLRSPTHYSSCRWPLL
LDPSNQALIWLDPLPLAENRCLAPAPTEGRGKGLM----RNQNTESK-MDMKEEDDDSEE
SNEAKDQTKEQKAEERKNEQE---------K------EQEENEEKE-EKTESQGSKPAYE
TQLPSLPYLSVLSGADPEL--GSQLQEAAACGLPVLLTNVE--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLSLCAMEK----VLGCELLKGLNVLDLGLNMKILEEQMLHEILC
RECPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQ--NPKRQKPAKFLRNMVRAQGK
LCQLRAHYEELEGQKLQEMVSWAPYRPVVWHGIAMVKALSQLQNLLPLFRMSPEKWLAVT
KQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQV
TGKASELERLALWPGLAASPSTVHSKPVSGVTRP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 5029)

AWLGPKAWHECEMLELLPPFVGLCAS
LAGHSNAWQAYLSLSSTVLGPAPG--PGPEPLSLLQKLILWRVLRPECLAGALADFTTSL
LGRPLDENMGAPTLPFKHSRATQPMLILLPLPGHPTATLHPLTVIQNLAAKYQQ--GQKH
LQVIALGSEVWDPVSVVVSTLSQAMYEGHWLVLDNCHLMP----HWPKELLQLLLELLGR
AKVVADLESEQLLGQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE
LGHVLIDSVELAQQGLYMQP-PTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLTQV
LQTQDQLWASLSNPHAAMQELAASVFYGGPLGDTEDREALFSLTQACLSPSSRNWVQPHT
PQSLLAMLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRLLLSA
LQRSSPVWVPETRGGA---QLAERRLRHRLVQVNRRLESLQDLLTNLVRQDES---GAPK
SVLGPNARRPLEGVLETEALELSRLVGTLQRDLDCLLQQLKGAPPCPSSRCAAVAHALWT
GRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGLGADANSDVPERVFHLSAFRHPR
RLLLALRGEAALDQ-----NVPSSNFPGSRGAVSS-----PLPYKRLEMNSNPLHLRVEN
GPNPTVPERGL-LLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPPP
ADLSVYSCPVYMGGPLGNTKLQSRNIVMHLPLPTKLTPNTCVQRRVHVCSPPLS

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-------MLAWW----------VGCPCLPPTGLPVLLTNME--LGLGCQELQWLLQREQL
SPPQVQPGFCLYLSTTLPLSALEK----VLGCELLKGLNVLDLGLNMELLEEEMLHEILR
IERPELESHWQDLKIRALDTCEAVEAAEERLLLMLLLQ--NPKHQKPVKFLRDMVRAQAE
LCQLRVHREELEDLKLREVALWAPYRRVVWHGMAIIKALSALQNLLPLFRTSPENWLAAT
KQALNSMKQRETHQREDLPSHLLQLRTQLTRQFLDSTVATLGLTQLPLVGALGALALLQV
ARKAPLLERLALWPGLAASPSTGYSKPGPGVARP

PF03028 // ENSGT00910000144015_1_Domain_9 (4235, 4994)

AWLGLRAWHECGMLELLPPFAGLRAS
LAGHSNVWQAYLSLSSTVLGPAPG--PGPDALSLLQKLILWRVLRPECLAGALADVTTSL
LGRPLDENLGACTIPFERSQATQPMLILLPPPGHLTATLHPLTVIQKLAAEHKQ--GQRH
LEVIALGSEAWDPVSVVVSTLHQAMHKGHWLVLENCHLLR----HWPKELLQPLLGLLDG
AKVVSDLELGLLLDQLASRKVATVHRDFRLWLIVSAEAVASLPAVLIQHSMPIFWDQSLE
LSHILIDSMELAQQGLYMQP-PTRALPLLLLHGLLLHRQLYGMKLQAHRGRWSQVTLTQV
LQIQEQLWASLSNPSAAMQELAASVFYGGPVGDDKDREALISLTQACLSPSSGSWTQPHT
PQYLLATLIPSPELGEPDAMADCKAQMHLLPTPPEPQICGLSAGPQAWLLRRRSRALLSA
LQRSSPAWVPAAREGS---RRAERRLRQRLVQAERRLESLQALLTETTRQDRS---GVEW
VGPRLNARRPLEGFLETEVLELKQLVGTLQSDLDCLLQQLKGAPPCASRRCAAVAHALWT
GRLPPPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYLGVA----TEVPERIFHLSVFRHPR
RLLLSLRWEAVFAM-----YVPSSNFPGCQGSSST-----QFPHKHTELNSKPLHLQVVN
DPNPTVPEMGL-LLIGLQVWNAEWDPLAGALQDSPSSHPSPLPPVSISAQAQGTNDLPPP
AGLAVYSCPVYMEGPLGTTRLHSRNILMHLPLPTKLSPATCVQRRVHVCSPPLP