ENSGT00900000141032_1 : Linker Region Query Results

MEPEDLPWPGELEEEEEEEEEE-EEEEEA----------------------AAAAAANVD
DVVVVEEVEEEAGREL---DCDS-HYGPQHLESIDDEE---DEEAKAWLQAHPGRILPP-
------------PSPPQH----RYSEGEQTSPEK-------IVPLTCHVW-QQIVYQGNS
RTQISDTNVVCLETTAQQGSGDDQKTESWHCLPQEMD-SSQTLDTSQTRFNLRTEDTEVT
DFPSLEEGI-LTQSENQVKEPN--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFAPD
SLFHQSELSFASLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHPL-
IGSTAVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDRYD-DLCSYMSWKTRKDTQWP
ENNLADKDQVSVATSSDITDENIATKRSDHFDAACSYGQYWTQEDSSKQAET--------
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---------------------------------------------------YLTKGLQGK
A-ESDVITLDGLNE-----NAVV-CSER---VAEL-------------------------
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--------------------------QRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDTSKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLAVSSLL----ET
TTGQHTADTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQ
GLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLE
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTG
TATVLSTPHSHREKPGIFYQQE--FADSHQTEETLTKVSATPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYPQE-LADSHLPEEGLKVSA-IAGPADQKTGLPTVPSSAYSHRE
KLLVFYQ-QALLDSHLPEEA-LKVSAVS-----GPADRKTGTPTVTSTSSASSSLGEKPS
AFYQQTLPNSHLTEEALKVSVVPGP-GDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVYYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTIPSGSFSHREKPSIFYQQELPDSYATEKALKVS-TGPGPADQKTEIPAV
QSSSYPQREEKPSVLYPQVLSDSHLPEESLKVSAF-PGPADQMTDTPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGLADQKTGTPTVTSTSYSQHREKPSI-F
HQQALPGTHIREEAQKVSAVTG-PGNQ-KTWIPRVLSTFYSQREKPGIFYQQTLPGSHIP
EEAQKVSPVLGPADQKTGTPTSTSAS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAS---------------------------------------------
-----------------EPVDQ-TT-G---TPAVTSTSYSQYREKPSI-FYQ-QSLPS-S
HLTEEAK--NVS-AVPGP-AD-QK-TV-IPI-LPSTFY-SH-TE-KS-GV-FY-QQV--L
PHS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VAPEPVDQTTG-TPT----VTSTSYSQHREKPSIFYQQSLPGSHLTEEAK
NV------SAVPGPADQKT-GIPTLPSTFYSHTEKPGS---FY-QQ-V-LP-HS-H----
LPEEALEVSVAPGP-VD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPDGHLPEESLKVS
VAPG-PVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSG--------PT----E
KKTDIPAGPL--GSSALGEEPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETL-LVHS
TTYSNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSYREKPIV
FYQ-QALPDSQLTQEALKVSAVPQP-ADQKTGLSTVTSSFYSLTEKP--NIPYQQELPDS
HLTEKALKVSYVPGPADQKTGVSTVTSTSYSHREKPIISYQRELP--HFTEAGLKILRVP
GPADRKTGI---NILLSNSYPQREHSVISYEQELPD--LTEVTLKAV---GVPGPAD-RK
TGIQIASSSSYSNREKASIFHQQELPD--VTEEALSVFVVPGQGDRKT-EIPTVPLSYYS
RREKPSVISQ--------------------------------------QVLP--DSHLTE
EALKVSPVSIPVEQK-TGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTQFPAATLSSYSQ
IEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPVSLSSSYFHREKSNI--FSPQELPGRHVTEDVLKVSTIPGPAGQKTV
LPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDSLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DVGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENMALKRCNFPA--PLA
PFRDISD-V--SFIQSKKVVCFKEPSSTGVS--NGDLF-QRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCRRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VTR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EYPQLDSHPCA-FR
SAEPSEMTRG-RQNPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLQMPFH---EKMDPWLSELV-----EPAFVPP---KEVDFHSSSQMPSPEPMK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
TSSPSSFKMHSNSQDK--EVTILAEGRRQSQKLPVDFEHSFQEEKPLERSDFTGSHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVSRSSSRLGVKEKNVTITPDLPSCIFLEQ
RELF--EQSKAPRAEDHVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQMRENHSPLPQGQDSISSDLPSPISLEQC----QS-KAPGVDDQMNKHHFPLPQGQD
CVVEKNN-QHKPKSHIS-NINVEAKFNTVVSQSAPNHCTLAAS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDERFHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVAQDQESLGFLGPKSSLDFQVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSADRLPEKMK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEIIEPGNQ-KLRKAPVKFVSSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQLPPSP--DSKSDTTVESSHSGSNDAIAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLQNENADASVQVLITGDENLSDKKQQ-EIHSTRAVTEAAQ
AKEKESLQKDTADSSAAAAAEHSARVGDPEMKNLPDTKAI---TQKEEI-HRKKTVP--E
EAWPNNKESLQINIEESECHSEFENTTRSVFRSAKFYIHHPVHLPSDQDICHESLGKS--
---VFMRHSWKDFFQHHPDKHREHMCLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVMDTTKSQ-ARDYPEHNGQISDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERSV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKSKVLS----------HHRAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRHIQVANHVISSDSISSSASSFLSSNPTFCNKQNVHML
NKGIQ-AGNLEIVNGA-KKHTRDVGMTFPTPSSSEAKLEEDSDV---------------T
S-WSEEKREEKMLFTGYPEDRKLKKNKKNSHEGVSWFVPVENVESRSKKENVP-NTCGPG
ISWFEPITKTRPWREPLREQNCQGQHLDGRG----SLAGPGREAGRDLLKPFVRATLQES
LQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDALFNIDRERQGHQNRMCPLPKRV
FLAIQKNKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEQAEESANQEE-----------------------DE----VVE
VVEVVEEVEEGEGREL---DSDF-NYESQPRESTD---DEDDEEAKAWLQAHPSGSLLS-
------------SSRPSH----RSLEDERTGPEK-------VVPLTCHVW-QQSLYQDNS
GIQISDANVVSVKKTAQWDSGDDQRTESWHCLPQEMD-SSHTLDTTHTSFNMREERTKVT
GFPSLEEGV-LTQPENQVKEPK--RDLLCSPLLVIQDNFASPDLPLLTCLTQDQ-ELGSD
SLFQQSELDFAPLRGIPGKSEDTEWFSRPSEVSEAVFQAASEVASDLVNSCISVSQHSL-
LGSAAVGSQRSFLRPEQGTKEETVSSDTDDELQTSEDFDSCD-ALCSYVAWKTQE-VQEP
EASLADEGQVSVSASSDTSDEYMTSKERDSFDDSYSYVQYRKQKALQ-QSGKYLTSKDHD
SYSDSSDTIDKN-KI-PEGSDNFSAPFSCMPWNKQETSHHPETYV-----ISKD----RV
SFPHEVAPRFNNKMSHSVLCCLLERRGEGISL----------TASSHFFDSVYLKAPAEN
EVKDMTDSLEGCERNEEGQGKELSQGFELKESRSTLVFSEVHPRSSEIQSIESVVVPDN-
-SIQVSEIHTH-CRGPGTSKMEVSGGPLQT----LKSNLDETSEQLYFQGERDQ------
----KATSAFSGKSVDA----------SENVAFEAVIASIEPSKKESTVNEIQTDINKSL
IKNSQESESKNPYLSLLNYNDES---SFFD-KLSHPCY-------ESTPRVFELAASKPL
L----LKKDNGDSSFYWHPNLKSL-PSAPQEMFIKPLSLIPEWKSSA-------SLCEKS
HSQAVGLGKAQSALFQCDI-GNEPFLPIGKIESVPVLDLTEKVGSSNIF-YPLKVWTSDS
LVLQDLKQQTLEEVADSSNYILGKNINSSNIIESPSAGWTVGSSFSANLVTC-DAKSQGT
LPVTSNASLVAVGQETLLKADVGQDKIPRPMGAKSSFTIHTIMQ----NDSCFLEGLQVK
A-ESDICTLDDDTESCSLDENAVVRSTR---VADLQREVRLNKMMVGGNVVFSSIISGNG
IVTCFYFTSSVAQVCDQGDLTGEYIELAGLKNVLD---DLEVCDSFLHWQSALQLSSKQE
SDFQELVDHSNTDINQSFSSVLPPFVPHELTRELEYHYSDLRMLRVSPDTVQKTLKHLA-
GDTSKGG----------------------TAEITQS------------TLKPGI------
-------R--------------------DS--DIGSHFSLFPEDFPQLALRFPQ----ET
TIGPHT-DILSQQA-LDSHTTEKTLKVSTVHELADQKTGISTVPSSSYSQRGKPGIFCLQ
YLPDRHLTEEAPKVLAVLGPADQKTGIPTVFPSSYPLGEKHGIFYSQALPDSYVT-----
------------------------------------------EEALKVSAVPVSADQRTE
KITVPSTSYLQREKHVNFSQQQ--SSDSHLTEQAL-KVSVVSGPAGENTGI------PIL
PSVS-SSLGEKPS-VFYQQA-LPDSHLIEQAQKVSA-VPGPVDQKTRIPAASSTYYSYGE
RPQIFYQ-QTLPESHLPEQA-LKFSAAP-----GSYEQKTGIPTVTSTP---YSHREKLN
LFCQQELPDSSLTEQAQKVSPVTGS-AEQKTGIPTLTSASHSHREKPNLFCQQELPDSSL
TEQAQKVSPVPGPAEQKTGIPTLTSTSYSLGEKPSLFYQQELPDNPLTEQAQKVLAIPGP
-DDQNT-GISIGSSRPYSLGEQPNIFSQQVLPDSHLTEETLKAS-SAPRPGDAKTGVPTV
PSSSYSPREKSG-IFYQQVLPGCHLSEEALKVSVA-TVPAEIKSGLPSEASNFYTER-EK
TSIFY------QQELPDSHLTEQA-QKVSPVTGPAEQKTGIPTL-TSASHSHREKPNL-F
CQQELPDSSLTEQAQKVSPVPG-PAEQ-KTGIPTLTSTSYSLGEKPSLFYQQELPDNPLT
EQAQKVLAIPGPDDQNTGISIGSSRP-------YS-LG-EQ-PS-IF-SQ-QVL-PD-SH
-LTE-ETL-KASSAP-RPGD-AKTG-VPTV-PSNS-YSPR-EKSG-IFY-QQV-LPG-CH
-LSE-EAL-KV-SVA-TVP-AEIKS-GL-PSE-ASS-FY-TEREKTSI-FYQ-QELPD-S
HLT-EQA-QKLS-LVPGP-AD-QK-TE-IST-VTSASY-SH-IE-KP-FI-FY-PQD-L-
PDS------------------------------------------------HLSQE-S-L
K-VTAV--SEPV-DK-K-TG-IPV-VP-STSYSQREKP-II-FYP-QAI-PD-IHLTE-E
AL-KVS-AIS-GS-ADW-KTG-IPT-VSS-IS-S-SH-TEEPVSFSLQALAGSLLLEEAL
-K-V-S-VL--PGPADQKA-GLSSEPPSSYSHGEKP-I-I-FY-PQ-G-LT-DS-Q----
VPQETLEVSAVPGP-AA-QKTGLPSEPSSCD-SHKEKP-IIFCLQGLTDSQVPQEALKVS
TVPG-RADQKTGLPSELSSSY-SHREKPIIFSSQGLTDSQIPQEALKVSA-VRGPADQKT
GLPSE----SSSPYSHREKPIIFYSQGLTGSQVPLEALKASAVPG--------PA----D
QKTGLPSEPS--SSYSHREKPIIFYPQDLTDSQVPQEALKVSAVPGPADQKTGLP-SEPS
SSYSLGGKPVIFYQQA-LSDRHLTEEAVNISASPG-PADQETRVSTVPSISYSHIEKPNV
LYQ-QPLSDSQLPVEALKVSAVSGP-GDQKTRKPTVTSTSYSHREKEKPIISYQQELPD-
-LTQEALKVLKVPGLGGQKTGIPAVTSTFYSHREKPIISYHQELSDPN--EGALRVLGTP
GPADQKTGI---QIGPSTSYSHRESPIFSYQKE--SSDITEETWKVS---PVSGPAN-QK
TEIHIIPSSSYSYREKDSILYQQELPD---------------------------------
---------------------------------------------------------VTE
KVLKVFALPGPADQK-TEIPTGPSSSYSH--KEKLNISPVILPDVQKTEFLTAPPSSYSK
REKPKISTVSGPDDQKTPLPTVFHNSCSQNF--------------EIEDILKIS-PVPEP
IVVN-----SGIPIPLSSSSSHREKSNI--FYPQELPDKHLAEDALNISSIPVPADQKSL
LPTAPPGSFSHREKPNLFYQQDFPDRHLPEDSVMFSRGLGQADQITGLSTVTPGTYSHS-
---EKQKLV-SDH-VQMLIDNLDSP-N---SSIISSS--MPLS-SQADG--RVIISKPES
SRFE----GVGS---VEIQDTSN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLV
PFRDVSD-I--SIIQSKKMVCFNEPLTAAES--NSDLP-RRQPF---TEESPS-NKCIQK
DISTQ--TNLKCQRGI-ENWEFISSTTL--RSPLQEAESK-AGVTLD-ETLRQCRAA-QS
VMR-SEPEGY-SGTIGN-KIVIPMM-TIIKSDSS------SDASSCSWDSNSL-------
ESVSD-VLLNF-FPCASPKTS-LTD--SREEESVSESDDCGGSNVDSLAAHVKNLLKCES
SLNHAKQILRNAEEEECRVRA--RAWNLKFNLAHE--CGYSISELNEADRKKVEEIKAEL
FSHGRTADLSKRLPSPQGIRCNPEAVCGHIIIESHEKGCFRTLTA-KQPQLDSHPYV-FR
PADPSDIIRG-QRSPSSWKTRHINLSK-SLDQSNPHFKVWNSLQLRSPSPFQNFTADDFR
IRQGLRMPFH---EKIDPWLSELV-----EP--VPP---EEMDCHSSSHMLPPEPMK--K
FTTSITFASHRHSKCFSDS--SVLKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLEQK
TSSPSSFKIVSHSPDT--AVTILAESSRQSQKLSI--EHSQQEEKLLERSDFKGSDSEPS
TSAKYSSVKEVHFSDNH-TLISVSRPSSTL---------GVKEKTVAITPDLSSHVLLER
QELF--EQSKAPHTDHRVRKCHSPPPQHQDYVAPNLPCRIFL--EKRELFEQSKAPHL--
-DHQMRENQSPFPQGQDYIASDLPSSIFLEQRQLFEQS-KAPDVD-HMGKYHSPFRQGQD
YVVEKNN-QHKFKSYISNMINVEAKFDSVVSQPVPNQCTLVTS--ASTPPSNRKALSCVR
ITLYPKTPSKVDSGTLDRRLHSLDPASKTRMNSEFNSDLQT----ISSRSLEPTSKLSAS
KPVAQNQESLGFLGLKSSPDFQVVQSPLPDS-NTISQDLKTIPFQNSQIVTSRQTQVNIS
DLEGYSSPE--GIPVSADRLSEEIK-TPFSAFSGKLS-SDAVTQITTESPGKTTFSSEIF
INAEDHGFESPEPSTQ-NVDKVPVKFVSSSSVQQITHPHGT-------------------
---DAQPSLLPYKPPGSTRMYYVPQLKQIPSYL--DSRSDTTIESSHSGSNDAIAPDFPA
EVLGTRDDDLS--------------------------------------IPADTKHKEGI
YSKRAVAKPSFS---VGKNPPQKDNADAEVQVSVSGDASLSDKNQKKEIYSKKAVAKAAQ
PEEKEFLETATAGSSGAAAAEPSARLQNIKIESPPDTEAI---KQNEEI-HSKRTVP--K
EAWTEDQESLQIDIAESRCHSEFENTTHSVFRSAKFYFHHPVHLPTDQDVCHESLGRS--
---VFMRHSWKDFFQRHPDKQRGHTCLPCPDENVEK-------TKADYTRI-ESLSINVN
LENK----EVMHSAKSQ-ARDYPKSDKQISDP--KRDHKVTPELATQHTVSLNELWNKYQ
ERQKQKKPPE-----FSDRKELSLVERLDRLAKLLQNPITYSLWA-SESTQDDSRGERDI
K-------QQQKIKLQKKKRYKSLEK-CHKNTGELKKSKALS----------PHQAGRSN
QIKIEQIKFDKYILRKQPGVHY-INNTSSDSRP-SDE-SELLTDTATNILSTTNSPVESD
ILTQTDKEVTL-QERSSSISTIDTARLIQAFGHERVCLSPRRIKLYSSITDHQRRYLERR
SKKNKKALNTSHPQMTSEHTRRKHIQVANHVISSDSISSSTSSFWSSSPTLCNKQNVHML
NKGVQ-AGNLEIVNGV-KKHTRDVGMTFPTPSSSEARVEEYSDV---------------T
S-WSEEKIEEKSLLTGYLGDKKLRKNKQSCSEGVSWFVPVENVKCGPKKENLP-KLYGPG
ICWFAPITNTKPWREPLREQNWQGQHMDSHG----SLAGPG----RDPPRPFVKATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLQNMLQSEREALFNTVREWQGCQDPTRRLLKRG
FLDAQKNRPIGKKEMIQRSKRI-YEQLPEVQRKREEEKRRLEYKSYRLRAQLFKKKVTNQ
LLGR--KVPWN---------------------------------------

MEPEDLPWPGELEEEEEEE---EKEEEATAAAA------------E-----AAAAATNLD
DVVVVEEVQEEAGREL---DSDS-HYGHQHLESTDDEEDEEDEEAKAWLQAHPGRILPL-
------------PSPPRH----RYSEGERTSLEK-------IVPLTCHVW-QQILYQGNS
RTQISDTNVVCLETTAQQGSGDDQKTESWHCLPQEMD-PSQTLDTSQTRFNVRREDTEVS
DFPSLEEGV-LTQSENQVKEPN--RDLFCSPLLVVQDSFASPDLPLLTCLTQDQ-EFASD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTTVGSQCPFLPSEQGNNEETTS--SVDELKIPKDCDSYD-DLCSYMSWKTRKDTQQP
ETNLADKDQVSVTSLSDITDENIATERSDHFDAAYSYGQYWKQEASPKQAET--------
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---------------------------------------------------YLTKGLQGK
A-ESDIITLDGLNE-----NAVV-CSER---ITEL-------------------------
------------------------------------------------------------
--------------------------QRKLTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDASKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLTVSSPL----ET
TTGQHT-NTLNQRPLADTHLTEETLKVTAIPEPAYQKTATPTVLSSSHSHRGKPSIFYQQ
GLPDSHLTEEALKVLAAPGPTDQTTGIPTLTSTSYSHREKPGIFYQQELPESNLTEEPLK
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQILPDGHLTDQALKVSAMSGLADQKTG
TATVLSTPHSHREKPGIFYQQE--FPDSHQTEETL-KVSFTPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYPQV-LADSHLPEEGLNVSA-VAGPADQKTGLPTVPSNAYSHRE
KLRIFYQ-QALLDSQLPEEV-LKNSAVS-----GPADRKTGTPTVTSTSSVSSSLGEKPG
AFYQQTLPNSHLTEEALKVSVVPGP-SDQKTGIPSAPSSFYSHREKPVIFSQQTLPDFLF
PEEALKVSAVSVLTAQKTETPTVSSNSHSHSEKSSIFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTATVPSGSFSHREKPSIFYQQELPDSHPTEKAVKVS-TGPGPADQKTEIPTI
QSSSYPQRE-KPSVFYPQVLSDSRLPEESLKVSAF-PGPADQTTDSPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGPADQRTGTPTVTSTSYSQYREKPSI-F
HQQALQGTHIPEEAQKVSAVTG-LGDQ-KTWIPGVLSTFYSQREKPGIFYQQTLPGSHIP
EEAQKGSAVPGPADQKTGTPTPTSTS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAY---------------------------------------------
-----------------EPVDQ-TT-G---TPTATSTSYSQHREKPSI-FYQ-QSLPS-S
HLTEEAR--KVS-VVPGP-AD-QK-TG-IPS-LPSTFY-SH-TE-KP-GV-FY-QQV--L
PDNHATEEALNISVAYEPVDQTTGTPTATSTSYSQHREKPSIFYQQLLPSSHLTEE-A-R
K-VSVV--PGPA-DQ-K-TG-TPT-ST-STFYSHTEKPGVFYQQ----VLP-HSHPTEEA
LNIS------VAYEPVDQTAG-TPT----ATSTSYSQHREKPSIFYQQSLPSSHLTEEAK
NV------SAVPGPADQKT-GTPTLPSTFYSHTEKPGV---FY-QQ-V-LP-HS-H----
LPEEALKVSVAPGP-AD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPDGHLPEESLKVS
VAPG-PVDQTTGSPTVTSPSYSQHRAKPGSFYQPALLGSQLPEEALRVSS-APGPADQTT
GIPTI----TSTSYSLGEKPIIIYKQAFADGHLPEEALKVSIVSG--------PT----E
RKTEIPTGPL--GSSALGEKPLTFYQQALLDSPLNKEVVKVSAAPGPVDQKTETI-PVYS
TPYSNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSHREKPVV
FYQ-QALPDSQLTKETLKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NTSYQQELPDG
HLTEKALKVSDVPGPADQKSGLSTVTSTSYSHREKPIISYQQELP--RFTEAGLKILRVP
GPADQKTGI---NVLSSNSYPQREQSVISYQQELPD--LTEVTLKAV---GVPGPAD-QK
TGIQIASSSSYSNREKPSIFHQQELPD--ITEETFNVFVVPGQGDQKA-EIPTVPLSYYS
HREKPSVISQ--------------------------------------QELP--DSHLTE
EALKVSPVSIPAEQK-TGIPIGPSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQ
TEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPDILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRHVTEDVLKISTIPGPPSQKTV
LPTVLPSSFSHREKPDIFYQKDSPDRRLTEDALKISSALGQADQITGLHTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DLGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSST-------DLL-QRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EQPQLDSHSCA-FR
SAEPSEMTRG-RQSPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFH---EKMNPWLSELV-----EPAFVPP---KKVDFHSSTEMPSPEPVK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
SSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLSVDFEHSCQEEKPLERSDFTGNHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVGRSSSRLGVKEKNVTVTPDLPSCIFLEQ
RELF--EQSKAPHTDDPVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQIRENHSPLPQGQDSIASDLPSPICLEQC----QS-KAPGVDDQMSKHHFPFPQGQD
CVVEKNN-QHKPKSHIS-SINVEAKFNNVVSQSAPNQCTLATS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRCHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVVQDQESLGFLGPKSSLDFQVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSADRLPKKIK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEITEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAVAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLWNENADASVQVLITGDENLSDKKQK-EIHSTRAVTEAAQ
AKEKESLQKDTADSSAAAAAEHSAQVGDPEIKNLPDTKAI---TQKEEI-HRKRTVP--E
EAWTSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGRS--
---VFMRHSWKDFFQHHPDKQREHICLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVTDTTKSQ-ARDYPEYSGQINDP--KKDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGERKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERGV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKTKVLS----------HHGAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTATNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRRIQVANHVISSDSISSSASSFLSSNSTFCNKQNAHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPSSSEAKLEEDSDV---------------T
S-WSEEKREEKLLFTSYPGDRKLKKNKKNSHEGVSWFVPVENVESGSKKENVP-KSWGPG
VSWFEPITKTKPWREPLREQNWQGQHLDGRG----SLAGPGREDGRDPLKPFVRATLQES
LQFHRPDFISSSGERIKRLKLIVQERKLQSMLQSERDVLFNIDRERQGHQNRMRPLPKRV
FLAVQKSKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEAEEAE-----------------------------NL----DED
EVVMVEEMEEEEGRDL---DADL-NYESQRRESTD---DEDDEEAKAWLQAHPSGAL-P-
-----------LPPLPRY----RYSEGEL-TSPK-------VIPLTCHVW-QQPSYQDNN
ETQVSDMIVVSLEEKAQWASGDDQRTESWHCLPQEMD-SSHTLDTTQTRFNVREKGTEVT
NFPSLEEGI-LTKSENQVKEPS--RDLLCSPLLVIQDSFASPDLPLLTCLTKDQ-EFGPD
SLFHQSELDFARLRGIPGKSEDTEWFSRPSEVSEALFQAASEVASDLV--SFSVSQHPL-
TGSEAVESQRSLLTPEQRTKEETVASDTLDELKTHKNSDSYD-ALCSYMSWKTQEVIQEP
GTNLADVSAAS-----DTSDEYITPKGSDSFDASCSYAQFWKQEALQ-QSEKYLTRKDHD
SYSDSSDLIDKN-KI-PKASDSFSAPFSYMPWSKQEAS-----HHPEIGLISKD---HVS
FLHEVTPPFN-NKMSHSFLHCFLERGGRGV-P----------LTPDSHSKSVYLRAPTES
EVKQQMDSLEGYERDEDDLGKGVSQCFELKENRNTLMFSGMHPSSSEIQYIEN-VFPDN-
-SAKVSEGHTLC-RGHDSSMIEASVGP--LQTS--KSNSDETAEQLYFQEE-KD------
---QKATSAFGGKNVD-------VTEN-IAF--QAVIASIEPSKKESTVNEIQTDISKSS
TNDSQKSEQKNPDLFLLNYD----ENSFFD-KLNHSCY-------QSTPGVFESVASKPS
L----YKKDNGDSSLYWHPDLKSL-PSAPQEIFIKPVS--------LIPELKSSSLSEKS
VRQAVDLGKTQSALFQDDT-DSELFLPIGKIKSVSALDLAEKLGSSNII-YPMKVWTSDS
LVLQELKPQTFEEVADSSNYILGKNVNSSNIIEGPSAA--VGGSFSANLVAC-DAKSQGS
LPVIS-DAKAAVGQETLLKANIGPGEIPWPMGAKSSFTIHTVMQ----NDSYFVEGLQGK
A-ESDICTLDDAAECCSLDENAVVCSK---RVAELQ------------------------
-----------REICGQGDLTSECTELAGLKNLL---DDLEICDSSPHWQSSVELPSKEE
SSCEVPVGPSDTDINQSFSSALPPFVPHESTRELEYHSADLRMLRVSPDTVPGTLKHLT-
GDTSKGG----------------------VLEIPQS------------TFKSGIT-----
----TTPE--------------------DS-DTGSH-LSLSSEDFPELALRSPQ----VK
NIGQYT-DTLNQQTLTDKHL------TEETLKI-------STI----------------P
G--------------LV----DQKTGI---PPSSYLLGEKHSIFYPQALPGGHLP-----
------------------------------------------EEALKASILPVPTDQKTG
IPTVPAGSYSPEEKTGIFYQQG--LPSSHLPEEAL-KVSVLPGPADQKTGL------PTV
SSTS-YLHGEKPH-IFYQQT-LPESHLTEQAVKVSA-APGPSEQKTGIPTIPSTSYAHRQ
KPSVLY-QQELPDSHLTEQ-AQKISALP-----GLAE-QKSGI---S-------------
------------------------------AV-PSASYP---HREKPSILYQQELLNSHL
IQQVQQVSAVPLPPEQKTGFPAIPSTSYSHGEEPSVLYQQELPDSHLIQQIQQVSAAPGL
-AEQKT-GIPRVPSSSYSPREKSSILYQQELPDSHLIQQVHQVS-AAPGSPEQKTGIPTI
PSTSYSHREKPH-NFYQQELPDSHPTEQAQKV-SAAPGLAEQKTEISTVPSSSYSYRE-K
PSILY------QQELPGSHLTEQA-QKVSAAPGLAEQKTGIS-IVPSASYPYREKPSI-L
YQQELPDSHLTEQTQQVSAAPG-LTEQ-KTEILTLPSTSYSHQKTART------------
-------------------------S-------YS-HI-EK-PS-IF-YQ-QDL-PN-SH
-LTK-AH--KVPAD----------------------------------------------
------------------------------------------------------------
---------------PEL-AH-QK-SG-IPI-APPAFY-SQ-RG-KT-SL-FH-QQE-L-
PDS------------------------------------------------HLSDQ-T-Q
K-IS-A-ISGSV-DQ-N-TG-IQT-VP-SSSYS---------------------------
------------------------------------------------------------
-------------------------------HREKP-I-I-FY-QQ-E-LP-DS-H----
LTEEALKVSAVPRT-VD-LNTGIPTRS-SRSYSFGEKPGSIFYQQVLPDGHLTEEALKVS
SASR-PSDQKTGILSVPASFY-SYRERPSIFSPQALPGSHPSEEALKDSA-SPGLADQKT
RTLES----S-SSDLHREKSSIFYQQELPDSHLAGETLKVSGVSG--------PG----D
QKTGIPIVSS--ASYLHKEKPIILYPQALPDRHLIEEALNVSTDPGPADQKTGIP-VVTS
PSYSHKEKPIIFYQQA-LSDSQLTVEALKVSGAPR-SAAQKTGIP---------------
----------------------------------IVPSSSYSYRERP--IISYQQELPD-
-LTQVALKILEVPGPADQNIGITAVPSPPYSHGEKPIISYQKELPEPN--EDSLTHMGVP
GQADQTTGI---QTVPPASYSRRESPLFSYQKE--LPDVTEETLKVS---AVPGLVD-QK
IGLQTIPPGPHSYGEKANVFYQQELPD---------------------------------
---------------------------------------------------------LTE
EALKIFALPGPADQN-NEIPTGPSGSYSH--KEKLKIL----PDDQKTELPLAPPSSYSH
REKPKTSTVIGPDDQKTPLLTGVPNSYSQRVKSSIFYEQQLPDRHQSGDILKIS-PIAEP
TDVN-----SQLPIPLSSSYSHREKSNI--FYPEELPDKHLTGDALKVSTIPGPADQKTV
LPAIPSSSFSYREKPVVFYQQDLPERRLTEENLKFSSSLGQADQITGLSTVPSGTYLHS-
---EKHKL-VSDH-VQRLIDKLDSP-N---SSVISNN--MPLN-SRADG-G-VVVSQTES
LGFE----DVGS---EEVRGTEN--SSRT-LKEIQTLL-ME-AENIALRRCNFPVPVPLV
PFRDVSD-IS--FIKSKKMVCFKEPPTTDES--NGDLSQ-RQPF---AEESPS-NKCIQK
DISTQ-T-NLQCQRGT-ENWEFITSTTV--RNPLQEAESK-ARVALD-ETLRQCKAA-NS
VMR-SEPEAY-SGSFGN-KIVIPMM-TIIKSDSS------SDASSCSWDSNSL-------
ESVSD-VLLNF-FPCSTPKTS-MTD--SRDEEGLLESDDGGGSSVDSLAAHVKNLLQCES
SLNHAKQILRNAEEEESRVRA--RAWNLKFNMAHE--CGYSISELNEDDRRKVEEIKAKL
FGHGRTTDLSKGLQSPRGIGCHPEAVCSHIIIESHEKGCFRTLTA-ERPQLDSRPYV-FR
SADSSEMIRG-QRSPSSWRNRHINFSK-SLDQSASHFRVWNSLQLQSPSPFQNFIADDLK
ISKGLRMPFR---EKLDPWLSEL------EPACVPP---EEMDCHSSSQMLPPEPMK--K
FTTSITFSSHRHSKCFSDS--SFLKVGVTEG-SQCTGASLGVFNSHFTKEQNLPRDLKQE
NSFPSSFKTISQSPDK--AMTLLAENSRQGQKLSV--EHSHQEEKLIERSDFKGSHSKPG
TSANDSNFKEVHFADNH-TLISMGRPSSTL---------GIKEKNVTITPDLPSHIFLEQ
-ELS--EQSKAPHADHHVRKHHSPPPQHQDYVAPNLPCRIFL--EERELFKQSKAPHV--
-DHQMRENHSPLPPSQDFIAPDLPSSIFLEQRQLLEQS-KTPDVDHHMRKHHSPLPQGQD
YVVERNN-QHKPELHISDMINVEAKFSDVVSPSAP----VVTS--ASTPPSNRKALSCIR
ITLCPKTPSKVDSGTLDKRIHSLDPASKTRMNSEFNSDLQT----VSPRSLEPTSKLLTS
KPIAQDQASLGFLGPKSSPDLQVVQSPLPDS--NITQDLKIIPFQNSQIVTSRQTQVNIS
DLEEYFNPE--GTPVSADRSPEEIK-TLFSPFSGKLS-SDAVTQITTESPGKAVFSSEIF
VSAKDREHEIPELTTQ-KVGKGLVKFASSSSVQQITVPQST-------------------
---DVQPLLLPYKPSGSTKMYYVPQLSQIPSSL--DSKSDTTIESSHSGSNDAIAPDFPA
QVLGTRDDDLT--------------------------------------DAVNIKHKEGI
YSKRAVTKASLF---VGKKPFQKDNADAQVQVFITGNEDPSGENQKKESSSKRAVPEAAQ
SEEKEPLLKDTADSSTAAASGYSTQPQDSKIDNIPATKAI---KQKEEM-HSKKTVP--K
EAWPEEKKSLQIDIAESRCHSEFENTTHSVFRSAKFYFHHPVHLPNDQDFCHESLGRS--
---VFMRHSWKDFFQHHPDKEREQTFLPPPYQNMEK-------TKTDYTRI-ESLSINVN
LENK----EVKQTPKSQ-ARAYPKCDKQVNDP--KSDHKPTPELTTQPTVSLNELWNKYQ
ERQKQQKPPE-----FGAKEELSLVERLDRLAKLLQHPITHSLQP-SESTQDDSRGEQEV
QE-WSRRQQQQKNKLQKKKRYKSLEK-CHKNTSDLKKNKILS----------THQPGRSN
QIKIEQIKFDKYILRKQPGVHY-INNTSSDSRH-SEE-SELLTDT--PILSTTTSPVESD
ILAQTDKEVTL-HDGSSSISTIDTARLIHAFGHERVCLSPRRIKLYSSITDHQRRYLEKQ
SKKNKKALNTGYPQITSEHTRRKHIQVTD-CISSDSVSSSTSSFWSSSSTLCSMQNVHML
NKGIQ-AGTLEIVNGV-RKHTRDVGMTFPTPSSSEARVEEDSDV---------------T
S-LSEEKIEEKRILTSYFGDTKLRKNKQSCCEGVSWFVPVENVKSGPKKENLP-KFHGPG
ISWFAPITNTKPWREPLREQNWQEQHIFSHG----SLAGPG----RHPLKPFVRATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLQNVLQSEREALFNTVQEWQGCRNPMHQLPKRG
FLAAQKKRPVGKKEMIQRSKRI-YEQLPEVQKKREEEKRRSEYKSYRLRAQLYKKKVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEVEEVE---------------------NASVAATEETEEVHSSEE
TVRLEEEELEEAGPEVDLDDLDF-NSEFQPRESTD---EEEDEMAKAWLQAHPVHAGRAF
PLPP----------PPRY----LYAPVKQVSDAE-------VVPLTCHVW-QESSYQDNS
RAEFSNPSTVPLETTVQWDPGEDQRAESWHHLPQERD-SSQALNTSPSSIDVRIEETKAI
NFPSLEKGE-LTQSERPVMEPK--LDLFCSSLLVIQDNFAGSDLPLLTCLTQDQ-EFESD
SLFQQSEQEFAPLRGIPDKSEDSEWLARPSEVSEALFQATSETSSDLVNSCLSISQHPL-
TGSTTFGSQHSLFPSEQENNGENAPSNAPDDLKDPKDSDHYD-ALLSFMSWQTEKDTQQP
EGNLADKDQVSTSTLSDVSDESIGAKTHNDFDSVCSHTQYWKQEAFQ-QTEACLASKDEA
SFP---------------------------------------------------------
---CEVIPPPPDKTSYSFLRCMLERGKGDP------------FTSVNHLESVCLRTPSED
DLSPKMDPLESFGG-NEDLQKELSQYFKQKEIRNILASSEVHAKSPEIKFIGMGAVPDS-
-HERVSEAHI-LSRGLEISKL-----------ETVKSNLDETAEQLYFQEERNQ------
----KAASTFGEKNVDA----------TENVAFEAVIASIEPSKQESPISEIQTDINKPL
ADDSQEREPPKPDLPPLNYNDEK---SFMD-KLKHPKY-------QSTPGVFEPAASKPL
L----HKEDDGGSSLSWDPDLKSP-PNAPQNMLSKPLSVIPGLK--------SSPLSEKA
YNRAVSLGETQSPSFQYDV---------------SNLDLAEKVGSSNII-FTMKVSPSDS
W-----------------------------------------------------------
----------------------------------------------------------GK
A-ESGIVTLHGDVEYSSLYKTADVHSEK---VAELQ------------------------
------------------------------------------------------------
----RKVDHSDLGISQPFPSPLPSFVPQEPTGESKYYSPNLRMLRVSPDTLPTAPTLSV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------APGSVDQKMG
A-TVVSSTYSHEVKPGSFPQEE--LPDRHFIEETQ-KVSSASRPDGQKPEM------STI
YSSY-HSKGMK-P-VFYQHP-LSESHPGKEPLDVSA-VFGSTEKT-QS------------
-------S----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------TTLSDSHLTEEALPVS-VIPGRGDQKTPLPSE
LPVSYSYRDKNL------------------------------------------------
--------------------PENV-EKVSIDSGSADEKADIPTV-SSSSYQHKKKTI-VP
YHQEWPDSHVPAGTQKVSLVSG-PVDQ-KSGI----------------------------
-------------------------S-------HS-YG-EV-PG-VF-YQ-QEL-PD-SH
-SAE-KSTK---------------------------------------------------
------------------------------------------------------------
-----------T-LIPGP-AD-QK-TD-LST-VLPTSP-SH-TE-KP-IF-PY-QPT-L-
H------------------------------------------------------E-A-F
N-APSV--SKPS-DE-L-SG-IST-VT-SASHS---------------------------
------------------------------------------------------------
-------------------------------YKERP-S-I-SH-QQ-K-FP-DH-H----
LTEDAQKVSGTTGS-VD-QKTGTP----AVSYLQKERP-GIFYQQTLS-GPLSEEALQAS
AMTR-PADQSIAMPSVASTSS-LQREKPQIFYQQALPGGHLPGESLKVSA-APGPPDQNT
GVPVV----SPTSYLPGEESIIFYQPGLSGNPLSAESFKVPGISG--------LP----E
QKTSTPAGPA--GSYPIGEKPIIFYQNTLP------------------------------
-----------------------------MAAIPG-PTEQKIGTPAGPSGSHPVGEKSII
FYQ-QALPD--------EILGSVGP-TEQKTEIPRVPSTPL-YREIP--AVSYQQELPD-
-LTEEALRVLDVPGL---------TET--------------------------ALKTG-P
GATHQKTGA---PIV---SYSSRGKPSGFHQQE--LPSTE--------------------
------PLSYYPQR-EASAFSPQELPASHPTEEAL----------KTR-GTPTGPSSSYF
HREKFSDFYQ--------------------------------------KASPDHDHVLTE
NSLKASTVPGLSDQN--RRPAVLSGSYSQ--KEKHKISAADPLDDQKTELPTVTHRSYLH
REKPAIPSVVGPDDQKTPLPTAFHGSYPQKVKPVISVQKQLPDRDQSEDIPKIS-TVSEP
TVVN-----TGVPVPLSGSYSHREKSDTSYGYSQELPDRHL-------------------
----------------------------TEDALKVSGSLGQADQISGLPTVSPDAYSHS-
---ERHQLV-SEH-VQKLIDNLNSP-ES--CSLIANS--MPLNSQIDDG---VIICKPES
SGFG----DVGC---EEVRDTDR--GSKT-LKEIQTLL-ME-AENIALKRCNFPA--PLV
PFRDVND-V--SLIQSKKVVCFKEPSTTDVC-------TQRELF---TEEVPH-IECVQK
DIGTQ--TNLKCQRGV-ENWEFISSTAI--RSPLQRAEDT-ARMAFD-ETFRRYEAS-RS
VMR-SEPEGC-STGIGN-KIIIPMM-TIIKSDSS-SDVS---DGCCSWDSNLP----ESL
ESVSD-VFLNF-FPYTSPKTS-ITD--SREEEGLSESEDGCG-SVDSLAAHVKYLLQCES
SLNQAKQILRNAEEEECRVRA--QAWNLKLSLGHD--YGYSISELNEDDRRKVEEIKAKL
FGHGRATHVSEGLRSPRGIGCVPEAVCSHIVIESHEKGCFRTLTA-EQPRPDSRHSV-FR
SVESSDVTRG-QRNPSSWRGRHINLSR-SIDQSNTRFKVWNSFQLQSHPPFQKLAPDDIK
ISKGVGMPFH---AYMDPQPLGLV-----EPSCVPA---KEMDFPSSSQILPPEPKK--Q
FTTSITFSSHGHSKCISDS--SVFKVGVTEG-SQCTRPSLGVFKSHIPEEQISPRDLKQK
TSSPSSLKRHSHSP-----VTILAEGSRQRQKLPVDFDHSHQKGKLLERSDFKAGHSEPS
VSA---SFKGVQFSGKD-TIISPDKLSPTL---------EVKEKNVAITPDLPSCILLEQ
RELF--EQSHTPHTDHEMRKYSSPF-------CPDIASCIFL--EQRELFEQSNAPHVD-
--HENREDHSFFPKHQDCLDADLPSPDFLDQQ----QC-KSPDVDDHMRKQQFPLCQGQD
WVVEK-I-QHIPQSHFSNMINVEAKVSNLISQSAPDHCTA-----ASTSPSNRKALSCVR
ITLCPKTSSTLDCGTLDERFHSLDPASKTRINSEFNFDLRT----ISSRSLEPTSKLLTC
KPIAQDQESLGFLGPKPPPDLQVAQSSLPDS-KTISQDLKTKPPQNSQIVTSRQTQVNIS
DLEGYSKPE--GTPVSADGSREQSE-APFPTSSAKVL-SDAVTQITTESPGKTTFSSEIF
INVDNHGQEVLGPKAQ-----KPPKFASSSSVQQITASHGK-------------------
---DAQPALLPYKPSGSPKMYYVPQLKAVPSFL--ESKSDTTVESSHSGSNDAIAPDFPP
QVLGSRDDDLS--------------------------------------TTVNIKHTEGI
YSKRAVSK--------GKKPPRKDDAEAPVQVPVTGDQNVSDKIQK-AFISKQVVTKMTG
PEEKGSLW-DTAGYSS-------TTVQDGRTENLPGTKSI---EQKE-------------
-------------EICSECHSAFENTTHSVFRSAKFYFHHPVHLPHEQDFCHESLGRS--
---VFMQHSWKDFFHHHS----EHSCLPPPGPSAD-------KTKMDYTRI-KSLSINLN
LGDN----EKMHTIKNQ-ARDPKS-KRQTNDH--KKDQKVTPELTTQCTVSLNELWNKYQ
ERQKQQKPPG-----VCDKNELSLVERLDRLAKLLQNPITLSLQA-SESTQDESRGGRGM
RG-RTGRRQHPQKCKLQRKWPKSLEN--GRSTGDFRKSRVL-----------PHHGGKSN
QIKIEQVKLDKYIWRKQPGFNY-ISNTSSDSRP-SEE-SE-LLTESPNIFSSTTSPVDSD
VLTQTDRDVTL-NERSSSISTIDTARLVQAFGHERLYLSPRRIKLYNSVTNQQRRYLEKW
ANHSKKALNTGYPQMTSEHTRRRHIQVTNHV-SSDSI-SSADSFLSLDSTLYTEENVHML
NKGVQ-AGNLEIVTGA-KKYTRDVGVTFPTPSSSEARMEEDSDV---------------T
S-GSEEKAKEKKFLTNYLRDRNLRNHKSSSCEGVSWFVPVENRKSESKKENLP-KIYGPG
ISWFEPVTKTKPWREPLREQNWQVLCMSNRG----SLGGPGGDGGRVPLRPFVRATLQEA
LQLHRPDFISRSGERIKRLKLLVQERKLQSLFQSEREALFNA----------VRPLPRRG
PLATQKNKPIGKKEMIQRTKRI-YEQLPEVKKKREEEKRKSEYKSYRLRAQHYKTRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPDELEEEEEEE------EEEGKEEA--------ENASAAATEEAR---TSEE
TGRLEEEELEGAGPE--V-DLDF-NSESQLQESTD---EEEDELAKAWLQAHPDRPGQGF
SLTPPPT----PPPSSRH----QYRPVEHWGKRE-------VIPLTYRAW-QQTSYQDNA
RAQFSNSSTLLLEPEFQWDPEEVQRTESWHHLPQERD-SFQTLNISQTGID-RVEGAEVK
DLPSQEGGE-SVQAQCPVKEPK--LDLLCSPLLVIQDDFAAPDLPLLTCMTQDQ-EFEPD
SLFQQSELESFEVGGIPDKSEDIEWLARPSEVSEALIQATSESSSDLVNSCFSISQHPL-
T-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------EGLQGK
A-KSDVLILFGDAKYASIYENAGAHSER---ITELQ------------------------
------------------------------------------------------------
----REVDCSNLSITQAFPSSLPSFVPQEPTIESEYHSSNLRMLRVSPDTLLTTLT--Q-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------TTGSVDQKIG
A-AAISSPYSHGVQPGSFPQEE--LPDRHLTEEIR-KVSPAPRPAGQKPEM------PTV
PSSS-YSKGIK-S-VFYRYP-MSYSPQGKEPPNVSS-VSGSAENA-LPLTVTSVSQPQRE
TAKAFYQ-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------QTLSDSLLTAETLPVS-VIPESGDQKTHLLSG
FSLSYSHRGEDL------------------------------------------------
--------------------PEDV-VKVSTDSGSVDKKADIPTV-SSSTYQHKTKPGI-I
YYQEFPDSHVPIGTRKVVSQSG-AAGQ---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------K-TD-LSA-VPSTSS-SQ-AE-KP-VP-PS-LLT-L-
LGS------------------------------------------------HLPED-V-F
K-ASYV--CKSS-EE-P-SG-ITA-LT-SVSYS---------------------------
------------------------------------------------------------
-------------------------------YKGRP-N-I-SH-QE-K-FP-DS-Y----
LIEEAQKILGSTVT-VD-QKT-VT---------AKEKP-SVFYQQALPEGGLSAEDLQV-
-------DQNIAIPMVTSASF-SQREKPQVFYQEALSGGHLPGEP-------PGPPDQNT
EAPTI----SPSSYFPGEESIIFYQAGFPGNTPSVVPFKVSRISE--------LA----E
QKTNITTGPS--GSYSVGEKSIIFYHQALPDGHLSKEA-----SPAPADLKTGEP-PVYS
ASCSVEVKPIIFYQQP-LSDSPLTK-GHNVSVVPG-PTDQKTGIPAVPSTSQSYIERRSV
SYQ-QEFPNV--SEKALKVLGGVRS-TEQKTEIPVVSSALL-HTEVP--TISSQEDLPN-
-LTEEALQILGVAEE---------VPSVPS-RDKTRLISYQKKLPD--GTEVSLKSVG-F
GSTDQKTGA---HIV---SSSRREKSSGFHQQE--LPNTCGDALGTF----HPEPVA-QK
VGKPTEPSNI--QG-KASALSPQQLPASHLTGEALKVSDGSACVAQMP-EAPAGPSIFYF
HKERFSN-YQ--------------------------------------KASPDC--DLTE
NSLKSSTVPGLSDQK--KRPPVSSGSCSH--KEKHKISAADLLDAQAAELPTVIQRSCLH
REKLAISTVIKPDDPKIPLPTTCHASCAQKVKPVIFVQKQLSGRDQSEDIPKIS-TVSEP
TVAN-----TGAPVLLSSSYPYREKSDF--SSPKELPDRHP-------------------
----------------------------AKVDMQASSSLGQADQISRLPTVPPGTYSHS-
---EKYQLI-SEH-VQELIDNLNSS-ES--CLNADIM--MPSNSQIDDG---VIICKPES
SRFA----NVGC---EEIQDIDH--GSKT-LKEIQTLL-ME-AENMALKRCNFSV--PLV
PFRDVSD-V--SFVQSKKVVCFKETPTSDVC-------IQKDSF---AEEVPH-TKYVQK
DIGTQ--TNLKYQRNV-RNWEFISSATF--RSPLHEANGT-ARVAFD-ENFRQYRAT-RS
VMR-SEPEDC-STGIGD-KIIIPMM-TIIKSDSS-SDVS---DGCCSWDNNLP----ESL
ESVSD-VFLNF-FPYTSPKTS-ITD--SREEEGLSESEDGYG-SADSLAAHVKYLLQCES
SLNQAKQILKNAEEEEYRVRA--QAWNLKFNLGRD--YGYPVSELNEDDRRKVEEIKAKL
FGHGRTTHVSEVLQSPRGIGCLPEAVCGHIIIESHEKGCYRTLTA-EQPRPDSCHCV-FR
SVDPSDLIRG-HRSPSSWRGRHINLSR-SIDQSNPHFKIGNSFQLQSHPPFEKLVPDDIK
ISKGVGMPFH---EHMDPQPSELI-----EPTCVPA---KEMDFSSSSEILPSEPKK--Q
FTTSITFSSHQHSKCISDS--SGFKVDVTAG-SQCTGPSLGVFKPHIPEEQISPRDLKQK
ISSPSSLQRHSYTP-----VTILVDSSRQRQKLPVDFEHSNQKGKLLQRSAFNFSHSEPS
VSTNV-SFKGVQFSGND-TIVRQDKLISTV---------EVKEKNVTLTPDLPSCIFLEQ
G-----EESHTPHTDLHMRKCPSPS-------GLDIASCIFL--EQHKFFEQSQGQHVD-
-DHEMREDYSLFPKCQGYIAAD-PS-DFPDQQ----QC-KPPGVDGHVRKQHYPLSPVQD
CEVEE-V-QCIPQSYFSNMVNVEAKVSDMVSPDAPDHFTA-----ASTPPSSRKALSCVR
ITLCPKTPSKLDSGTLDERFHSLDPASKTRINSEFNSDLRI----ISSRSLEPTSKLLTC
KPVAQDQESLVFLGPKSPLDLQVAESSLPDS-KTISQDLKTTPPQNSQIVTSRQTQVNIS
DLEEYSKPE--GTPVPADGSQEQNK-APFTTSSGMLS-SDAVTQVTTESPEKMTFSSEIF
INADDRGQDIPYPTTQ-----NPSRFASSSSGQQITASQGK-------------------
---DAQPVLLPYKPSGSSKMYYVPLLKPVPSYL--DSKSDTTVESSHSGSNDAIAPDFPP
QVLGTRDDDLS--------------------------------------TTVNIKHKEGI
YSKRAASK--------GKQPSQKGNAEAPVQMPVTWDKNVYKENQD-EIISRRVVIETAG
PEEMPSQEKDLAGSSD-------ITVQDRKTGNLPDAKSI---KQKEGS-----------
---------L---EIEPECHSEFANTTHSVFRSASFYFHHPVHLPQEQDLCRESSGRN--
---VLTQHPWKDLFHCHS----GHSGLPPPGPRSD-------NTEMECTRV-KSLSMDLN
LGGH----EKIHTIKNQ-ARDTKEDKRPANDP--KKDQKVTPELTSQCPMSLNELWNKYQ
ERQKQQKPSG-----ACDNKELSLVERLDRLAKLLQNPITHSLQA-SESTQDDRRWGRGA
RG-WTGRRQHQQKGKQQRKWSKSLER--GHSTGDFRKSKVLS----------PHEGGKSS
QRNIEKIKLDKYILRKQPDFNN-VSNTSLDSRP-SEE-SELLLTDSPNLFSSTESPVESD
VLTHTGRDMPL-NERSSSISTVDTARLIQAFGHDRLYLSPRQIKLYSSVTNQRRKHLEKP
CKHKRKALNTACPQMTSEHTRRRHVQVANRIMSSDSV-SSAGSCLSLDSTLSNEENVHML
NKGVQ-AGNLEIVTGA-KKYTQDVGVTFPTPSSSEARLEEDSDM---------------T
S-WSEEKAKEKKFLSNYLRGKNLRKNKPNPCEGVSWFVPVENRKSESKKENLP-KIYRPA
ISWFEPVTQTKPWREPLREQNWQAQCMNSRG----SLGGPGRDSGQSFLQPFVRATLQES
LQLHRPDFISRSGERIKRLKLLVQERKLQNLFQNEREALFNT----------ARPLPRRV
LLAVQKNKPIGKTEMIRRTRRF-YEQLPEVKKKREEEKRKSEYTSYRLRAQHYKMKVTNH
LLGR--KVPWD---------------------------------------

MEPEDLPWPDELEEEEE-EEEEEGEEEEGKKEV--------ENASAAATEEAL---TSEE
SGRLEEFE--EAGP-----DLDF-NYESQRQESSD---EEEDELAKAWLQAHPDRPGSAF
SLPPPTPP--PPPLSPRL----RYTPVEHLGKTE-------VVPLTCRVW-QQSSYQDNS
RAQFSNSSTMLLETGVRWGSEEDQRTESWHCLPQERD-SSQTLAMSQTEIG-RVEGTEVP
DLPSQEGGE-PAQSQCPGKKPK--LNVLCSPLLVIQDNFAAPDLPLLTCLIQDQEEVEPD
SLFQQSELEFAPLRGIPDKSEDSEWLARPSEVSEALIQATSETSSDLANSCFSISQHPL-
TGSTTFGSQRSLFMFEQENNGETVPSNAPDELKSQKDSD--HDVLCSYMSWPPEKDTQQP
EGNLADKDQVSTSTLSDISDESIAAKRNNSFGVSCSCNQYWNQKALQ-QTEACLASKDHA
SFP---------------------------------------------------------
---CKITP-LPNKVPYSFLQHMLKRGKEAP------------LIADNHLENVCLRTPAED
EMSLKNESLEGFEG-NEDLQKELSQFFKQKETRNTWASSQVHTRYPEIKYIGTVAVPDS-
-KKQVAEPYI-LYRGLDISDCPL---------PTVKSNLDETSEQLYFQEERNQ------
----KAASTFDEKNVDA----------TENVAFEAIIASIESSNQESLISETQTDNTELL
ADDSEEKEPLKPDLSPLNCKNEI---SFID-KLKYLKY-------QSTPGVFEPTDSKSL
L----YKEDDA-SSLYLYPDLKSS-INAPQNMLNKPVSVTLELK--------S-SLSEKA
CNQAVGLE-TQSPSFQYGI---------------SNLDLTEKVGSSSIS-FAMKIATSES
WVLEDLKQQTFEEVADSSDYK---------------------------------------
-----------------------------------------------------LEGLQGK
A-ESGVLTRCGDAKYSSLYENVGAQSER---IAVLQ------------------------
------------------------------------------------------------
----REVGCSNLGISQASPSSLPSFVPQKPTSEPEYHSSNLRMLRVSPDTLLTTHT--H-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SAGSADQKIG
A-AVVSSAYSQEIKPGSFHQEE--LPDRHLNEEIR-KVSPALRTAGQKPEM------LPV
QSSS-YSKGMK-S-IFYQHP-VSHGHQGKEPLNVSA-VSGSADNK---------------
---AFHQQ----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------TLSDSLLTEETLPVS-IIPGLGNQKTPLPSE
FSLSYSHRGKNL------------------------------------------------
--------------------PEDV-VKVSTDSGSAHKKADILTA-SSRTYQHKMKPG-NI
YHQELPDSRVPIGTRKVAFESG-PAGQ-KSGV----------------------------
-------------------------S-------HP-YG-EM-PS-VF-YQ-QGL-PD-RH
-SAK-SPTK---------------------------------------------------
------------------------------------------------------------
-----------T-FIPGP-AD-QK-TD-LSP-VPPTSS-SH-AE-KP-VS-PY-QLT-L-
PGS------------------------------------------------HLPED-V-F
K-ASSV--CKSS-DE-L-SG-ITA-LT-SASYS---------------------------
------------------------------------------------------------
-------------------------------YKGRP-N-S-SY-QQ-K-FP-DS-H----
LNEEAQKILGTTGT-VD-QKT-VTPTMSSS-FLQKEKP-SIFYQQTLPDGGLSEEDLQVS
AVPW-PADQNIAIPTVTSAAF-SQREKPRIFYQQTLSVDRLPGEPLNVLG-PSGPPDQNT
GAPTV----TPSSYFPGEESIIFYQAGFPGNTLSAMSFKVPRISG--------ST----E
QTNIT-TGSS--GSYSVGEKSIIFYHQALPDGHLPQEA-----SPAPADLNTGEP-PMYL
ASCSVGVKPIIFYQQP-MSDSQRTK-GHKESDVPG-PTDQKTGIATVHSTSQSYIGRRTV
SYQ-QEFPDL--SEKALKVLGDVGS-TEQKTQIPVVSSALL-HKEGP--SA-YQEDLPD-
-LTEEPLQILGVSEE---------VPS----------SSYQRKLPD--HIEVFLKSVG-S
GSADRKTGA---QIV---SS-SREKSSGFHQQE--LPNTGGDAVDAF----HPEPVV-QE
VRKV-----------------------------------------QTP-GAPAGPSSSHF
HKEKLSD-YQ--------------------------------------KASPDR--DLTE
SFLKASTVPGPSDQK--KKPAVSSGFCLH--KEKHEISASALLNCQTAELLTVTQRSCLH
REDPAISTVIKPDDQKIPLPTTFHGSSDQKVKPVIFVQKQLRDRDQSEDIPKIS-TVSEP
TVVN-----TVLPVLLPGSYSHREKSDS--FYPQELPDGHL-------------------
----------------------------TEVDLKVSSGLGQADQISGLPTGISGTFSHS-
---EKHQLI-SEH-VQELMDNLNSS-ES--SCLSVDS--MPLNSQIDDG---VIICKPES
LGFA----NAGC---EEMQNIDR--GSKT-LKEIQTLL-ME-AENMALKRCNFSV--PLV
PFRDVND-V--SFIRSKKVVCFKESSTTDVC-------TQRESF---VEEVPH-IEYVQK
DIGTQ--TNLKYQRGV-GNWEFISSATF--RSPLQEAEGT-ARMAYD-ETFRQYKAA-RS
VMR-SEPEGC-STGIGN-KMIIPMM-TIIKSDSS-SDVS---DGCCSWDNNLP----ESL
ESVSD-VFLNF-FPYTSPKTS-ITD--SREEEWLSESEDGYG-STDSLAAHVKYLLQCET
SLNQAKQILKNAEEEEYRVRT--QAWNLKFNLGRD--RGYSISELNEDDRRKVEEIKAKL
FGHGRATHMSEGLRSPRGIGCLPEAVCSRIIIESHEKGCFRTLTA-EQPRPDSRHCA-FR
SVEPSDLIRG-HRSPSSWRGRHINLSR-SIEQSNPCFKVGSSFQLQSHPPFQKLLPDDIK
ISKGVGMPVH---AYMDPQPSELV-----EPTCVPA---KEMDFPSSSQILPPEPKK--Q
FTTAITFSSHEHSECISDS--SGCKVGVTAD-SQCSGPSLGVFKPHIPEEQISPRDLKQK
TSFQSSLERHGSTP-----VTILADGSRQRQKLPVDFEHSHQKEKLLQRLGFKVSHSEPN
VSTNVSNFKGVQFSGKD-TIVSQDKLTSTV---------EVKEKNVTVTPDLPSCIFLEQ
PELF--EESHTPHTDLQMRKYPSPS-------CPEIASRIFL--EQPKLSEQSKAPHVD-
--HEIREDHSFFPKCQDYIVAD-PSPDFPDQQ----QC-KPPDVVGHTRKQNSLLSQGQD
YELEE-V-QHIPQSYFSNMVNVEAKVSDAISQSAPDHCTA-----ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLGERFHSLDPASKTRINSEFNSDLRI----ISSRSLEPTSKLLTC
KPVAQDQESLVFLGPKSPLDLQVAQSSLPDS-KTIFQDLKTKPPQNSQIVTSRQTQVNIS
NLEGYSKPE--GTPVSADGSQEQSK-VSFTTSFGKLS-SDAITQITTESPEKTTFSSEIF
IHADDRGQGILDPMAQ-----KPSRLASSSSVQQIPASHGK-------------------
---DAQPVLLPYKPSGNSKMYYVPLLKRVPSYL--DSKSDTTVESSHSGSNDAIAPDFPP
QMLGTRDDDLS--------------------------------------NTVNIKHKEGI
YSKRAATK--------GKNPSQKGDAAAPVQMPITWDENVLDENQE-EVISRGVVIKMAR
PEEMSSLEKDLAGPSD-------ITVQDRKTENLPDTKSI---KQKKGS-----------
---------L---EIESECHSAFENTAHSVFRSAKIYFHHPVHLPHEQDFCHESLGRS--
---VFMQHSWKDFFHHHS----GHSCLPPPGPSSDK----LDKTKMDYTRI-KSLSINLN
LGDH----EKIHTIKNQ-ARDPKG-KRQANDQ--KKDQKVTPELTTECPVSLNELWNRYQ
ERQKQQSPSG-----ACDTKELSLVERLDRLAKLLQNPITHSLRA-SESAQDDSRGGHRA
RG-WTGRRQQKQKGKQHRKWSKSLER--GQSTGDFRKSKVFS----------PHQGGKSS
QFKIEQIKLDKYILRKETGFNN-VSNTSLDSRP-SEE-SE-LLTDSPNIFSSTDSPVDSD
VLTPTDRDMPL-NERSSSISTIDTVRLIQAFGHDRLSLSPRRIKLYSTVTSQRRRYLEKP
CKHNRKALNTACPQMTSEHSRRRHIQVANHMTSSDSV-SSSGSLLSLDSALSNEETVCMV
SKGVQ-AGNLEIVAGV-KKYTQDVGVTFPTPSSSEARLEEDSDV---------------T
S-SSEEKAKEKKFLSNYLQTKNLRKSKPNPCAGVSWFVPVENGKSGSKKENLP-KIYRPG
ISWFEPVTKTKPWREPLREQNWQAQCMNSRG----SLGGPGRDSGQVSLQPFVRATLQES
LQLHRPDFISRSGERIKRLKLLVQERKLQSLFQSEREALFHS----------ARPLPRRV
LLAVQKNKPIGKKK----------------------------------------------
--------------------------------------------------

MEPEDLPWPGELEEEEEEEE-EK-EEEATAAA-------------A-----EAAAAANLD
DVVVVEEVQEEAGREL---DSDS-HYGHQHLESTDDGEDEEDEEAKAWLQAHPGRILPL-
------------PSPPRH----RYSEGERTSLEK-------IVPLTCHVW-QQILYQGNS
RTQISDTNVVCLETTAQQGSGDDQKTESWHCLPQEMD-PSQTLDTSQTRFNVRREDTEVS
DFPSLEEGV-LTQSENQVKEPN--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFASD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTTVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDSYD-DLCSYMSWKTRKDTQQP
ETNLADKDQVSVTSLSDITDENIATERNDHFDAAYSYGQYWKQEASPKQTET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDIITLDGLNE-----NAVV-CSER---ITEL-------------------------
------------------------------------------------------------
--------------------------QRKLTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDASKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLTVS-SL----ET
TTGQHT-STLNQRPLADTHLTEETLKVTAVPEPAYQKTATPTVLSSSHSHRGKPSILYQQ
GLPDSHLTEEALKVLAAPGPTDETAGIPTLTSTSYSHREKPGIFYQQELPESNLTEEPLK
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQTLPDGHLTDQALKVSAASGPADQKTG
TATVLSTPYSHREKPGIFYQQE--FPDSHQTEETL-KVSFTPGLADQKTEI------PAV
QSSS-YSQREKPS-ILSSQV-LADSRLPEEGLNVSA-VAGPADQKTGLPTVPSNAYSHRE
KLRIFYQ-QALLDSQLPEEV-LKNSAVS-----GPADRKTGTPTVTSTSSVSSSLGEKPG
AFYQQTLPNSHLTEEALKVSVVPGP-GDQKTGIPSAPSSFYSHREKPVIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHNEKSSIFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPSGSFSHREKPSIFYQQELPDSHPTEKAVKVS-TGPGPADQKTEIPTI
QSSSYPQRE-KPSVFYPQVLSDSHLPEESLKVSAF-PGPADQTTDTPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGPADQRTGTPTVTSTSYSQYREKPSI-F
HQQALPGTHIPEEAQKVSAVTG-LGDQ-KTWIPGVLSTFYSQREKPGIFYQQTLPGSHIP
EEAQKGSTVPGPADQKTGTPTPTSTS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAY---------------------------------------------
-----------------EPVDQ-TT-G---TPTATSTSYSQHREKPSI-FYQ-QSLPS-S
HLTEEAR--KVS-VVPGP-AD-QK-TG-IPT-LPSTFY-SY-TE-KP-GV-FY-QQV--L
PDNHPTEEALKISVAYEPVDQTTGTPTATSTSYSQHREKPSIFYQQLLPSSHLTEE-A-R
K-VSVV--PGPA-DQ-K-TG-TPT-ST-STFYSHTEKPGVFYQQ----VLP-DNHPTEEA
LNIS------VAYEPVDQTTG-TPT----ATSTSYSQHREKPSIFYQQSLPSSHLTEEAK
NV------SAVPGPADQKT-GTPTLPSTFYSHTEKPGV---FY-QQ-V-LP-HS-H----
LPEEALKVSVAPGP-VD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPDGRLPEESLKVS
VAPG-PVDQTTGSPTVTSPSYSQHRAKPGSFYQPALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSYSLGEKPIIIYKQAFADGHLPEEALKVSIVSG--------PT----E
RKTEIPTGPL--GSSALGEKPLTFYQQALLDSPLNKEVVKVSAAPGPVDQKTETI-PVYS
TPYSNRGKAFIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSHREKPVV
FYQ-QALPDSQLTKETLKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NTSYQQELPDG
HLTEKALKVSDVPGPADQKSGLSTVTSTSYSHREKPIISYQQELP--RFTEAGLKILRVP
GPADQKTGI---NVLSSNSYPQREQSVISYQQELPD--LTEVTLKAV---GVPGPAD-QK
TGIQIASSSSYSNREKPSIFHQQELPD--ITEETFNVFVVPGQGDQKA-EIPTVPLSYYS
HREKPSVISQ--------------------------------------QELP--DSHLTE
EALKVSPVSIPAEQK-TGIPIGPSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQ
TEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPDILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRHVTEDVLKISTIPGPPSQKTV
LPTALPSSFSHREKPDIFYQKDSPDRRLTEDALKISSALGQADQITGLHTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DLGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NGDLL-QRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EQPQLDSHSCA-FR
SAEPSEMTRG-RQSPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFH---EKMNPWLSELV-----EPAFVPP---KKVDFHSSTQMPSPEPVK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
SSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLSVDFEHSCQEEKPLERPDFTGNHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVGRSSSRLGVKEKNVTVTPDLPSCIFLEQ
RELF--EQSKAPHTDDPVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQMRENHSPLPQGQDSIASDLPSPISLEQC----QS-KAPGVDDQMSKHHFPFPQGQD
CVVEKNN-QHKPKSHIS-SINVEAKFNNVVSQSAPNQCALATS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRCHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVVQDQESLGFLGPKSSLDFRVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSADRLPKKIK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEITEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAVAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLRNENADASVQVLITGDENLSDKKQK-EIHSTRAVTEAAQ
AKEKESLQKDTADSSAAAAAEHSAQVGDPEIKNSPDTKAI---TQKEEI-HRKRTVP--E
EAWTSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGRS--
---VFMRHSWKDFFQHHPDKQREHICLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----GVTDTTKSQ-ARDYPEYSGQINDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERDV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKTKVLS----------HHGAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTATNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRRIQVANHVISSDSISSSASSFLSSNSTFCNKQNAHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPSSSEAKLEEDSDV---------------T
S-WSEEKHEEKLLFTSYPGDRKLKKNKKNSHEGVSWFVPVENVESGSKKENVP-KTWGPG
VSWFEPITKTKPWREPLREQNWQGQHLDGRG----SLAGPGREDGRDPLKPFVRATLQES
LQFHRPDFISSSGERIKRLKLIVQERKLQSMLQSERDVLFNIDRERQGHQNRMRPLPKRV
FLAVQKSKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPGPGELEEEEKDVEEEK-----EEEEKTV---------EAAAVEEEP----ATS
VEIVTEEVEEEAGPEL---DSDS-NYEFQSRESSDEE-DREDEEAKAWLQAHPEVILLP-
-----------PP-PPRY----SYVRSARTCA----------------------------
----------------------EKKTESWQYLPQEIN-SSQTLDASQTGINVKLKGNEVT
NFPSLEKGV-LIQSEDQVKEPN--RDLLCSPLLVIQDTFASPDLPLLTCLTQDQ-DIGPD
SFFHQSELDFAPLRGIPDKSEDTEWFSRPSEVSEALFQATLEVPSDFVNSCFSISQHSL-
TEGLQGKA----------------------------------------------------
------------------------------------------------------------
----ESDVI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------TLDNDTECCSLDEKAVVSSE---GVAELR------------------------
-----------RETCDQYDVTDECVDLATLEDLLD-----DLCDSSLHLEPTLQQPSEED
SNFEKLVGHSNLGINQSFSSVLPPFILHEPTRESEHRSSNLRMLRFSPDTVPKSLKHLS-
GDTSQED----------------------IAEIIQS------------KLQSGIT-----
----TSG---------------------D--SDIGSHLSLSSEDLPQLAVSSHK-----N
TTGQPI-NTLNQKALPDSHQTAASLKVSHITELAEQKTGIPTEPPLSYSRVEKPNILYQQ
GLPDGHLTDQLLTDSVVPGPADQNTETATVPSPSYSHRDKPSIFYQQELPGSYLT-----
------------------------------------------KEALKVSAVPRAPDQKTG
IPTVSSTSNSNKEEPGIFYEQD--LPESHLIEETP-KVSGVPGPPDQKSRT------PHV
TSTS-YLQRKKHS-SLYQEG-LPDGHLPEQSLKVSA-VPESATWKTSIQTITSPSYSQKD
KPDLFYQ-QAFLDSHLTEET----------------------------------------
------------------------------------------------------------
----LKVSVASKPADQKIGITTVSSNSYSHGEKSHTLNLQALPESHLTAKNLKEPILPGF
-ADQKT-EIVAVSSTSNSLRE-NSIFYQQELAQNHLTEETLKVS-TAPGPSDLKTGILTT
HSGFYSQRGKPG-VSYQQTLSDIYTTKEPLKASPV-YGLTDLKTGTLAVSS-VSHSHREK
PSVFY------EQELADSHPAEKS-LEESVVPEPADQKTSISTV-TSISYSHREKP-I-S
YQSVLSDSHLPEETLKVSAVSG-PADQ-ISSIPTLTSA----------------------
-------------------------S-------YS-YK-EK-PS-IF-YE-DKL-LD-SN
-LEN-AL--EVSSA----------------------------------------------
------------------------------------------------------------
---------------PGP-AE-QK-IG-TST-VSFASY-SQ-ID-KP-GV-FY-KQA-L-
LKS------------------------------------------------HQAED-I-L
K-VSSA--PGPD-NQ-K-DG-IST-VT-STSYS---------------------------
------------------------------------------------------------
-------------------------------HKKDP-G-I-SS-QQ-E-LP-ES-Y----
IPRDSSEVSGSPRP-AD-QKTGTPAES-SNSYSLGEKY-VIYYQQVLPSSHLPEEALKVL
ADSS-TAEQKTGTPAGPSDSY-SPGEKPIIFYQPILPSSRLPEEALKVLA-DSAAKEQKT
GTPAV----SSGSYRLGEKPIIFYQQSLADGHLPKGVLKVFASPG--------PA----D
LKTEKSTVSP--TLYSLGEKPIIFYQQALPNSEVT-KGVKISVVPEPADQKTEISSTVTS
SSYSDREKN-ISYQWE-LPDSRLTEKAEKVSLGSE-PVNQKTGTPTVLSTSYSY---PSV
SYE-EVFPDL--NEESSKVLGVVGT-DEKKTGIQIVSSTPYSNKEKP--SVSYKEVFPD-
-LNKEALKVLGVLGPAKQKTEIQIVSSTPYSNREKPVVSYQQVLSG--VNEEALKIVDVS
EPSDQKTGI---YIVPSSTSSQGEQTFVSYQPYEELPDLPEVASKTA---EVSGPAN-QK
PRIQTVSSVSYSHEEKPSVFQQQEVPN--ITEDALNVVVLSGPDDQKI-RVPTTPFLSFY
SHKEKPSVSSPQEFPDSYLTEEALKISAVFLPAEQKAGTRTGPFDSSFHGVK--PSDLTE
ESLKDSAVARQADQT-NRVPTLPSNFYSH--EENPKISTVNAPDDQKTESPSTTHSSYLQ
KEKSNISTVIGLNDQTTPLQTVFYSSYSQRVKP----QQQLPDRVQSGDTLKIS-AVPEP
TEVN-----TGIPVPLSGSYLHRDKSNT--FYLQELPDRYLTEDALKVSTIPEPADQKMV
LPGSPPSSFLYSEKQNIFHQKDMPDRHLTEDTLKVSPGLRQADQITELPIVSSGTYLPD-
---EKHRLV-SEH-VQRLIHNLNSS-D---SSFRPNN--MPLNSQVDDG----VVTKPES
SGFA----DTGS---KEVQGTAN--SSKT-LKEIQTLL-ME-AENIALKRCNFSG--PLI
PFRDVND-I--SFIQSKKVVCFKEPSTIDVS--NDDML-QREPF---TEENSN-NRCIQK
DIDTQ--TSVKCQRGI-ENWECISSTTI--RNPLQEAESK-ARVALD-ETFRQYEIA-KS
VLR-SEPEGY-SRTIGN-KIIIPMM-TFIKSESS-SDASD-GNASCSWDSNLP----ESL
ESVSD-VLLNF-FPYTSSKAS-QTD--SREEEGVSESEDGGG-SVDSLAAHVRNLLQCES
SLNHAKQILRNAEEEEYRVRT--RAWNMKYNLADD--HGYSISELNEDDRRKVEEIKAEL
FGHSRTPDLSEGLQSPRGIGGTPEPVCGHIIIESHEKRCFRTLTA-EEPQLDSHSVFRCW
GREPSEMIRG-RQCPSPWRARHINFSK-SLDQNNTNFKVWNSLQLQSHSQFHNS------
VSKGFRMPSR---EKMDPRLSELV-----EPACV--------DFHSSTQIPTPEPMR--E
FTTSITFSSHRHSKRISDS--SVFKVGVTE--SQGTGASVGVFNSNVTEEQTPPRNLKQK
TTSPS-LKTLNHSPDK--DVTIVPEGNRQSEKLPVEFEHSHQEEKLLERSDFKVSPSEPS
SSANCSNFKEVQFSDNH-TLISMSRPNSTL---------GVKEKNITVTPDLPSVIFLEQ
RELF--EQSKVPHADHRVRKHHSPF-------CPNIPSCIFL--EQRELFKQSKPPHI--
-DHPMRENHSSFPHCQEYIASDP-PSIFLEQR----QS-KAPSVDDHMRKDHFSLSQGQD
CLVEK-N-KHMPQSHISN-INVEAKCNNVIYQLPPDHCTLATS--ASAPPSNKKALSCVR
ITLCPKTPSKLDSGTLHKRFYSLDSASKTRLNSEFNSDLQA----ISSSSLEPTSKLLTR
KSVAQNQGSLGFLAPKSPLDLQVAQSPLPDS-NSIAQDLKTVPSQNSQITTSRQIQVNIS
HLEGYSKPE--GTPVCADCSPERSK-TQFSAFSGKLS-SDAVTQITTESPEKTTFSSEIF
VNAEDYGHEILEPTIR-KLQKVPVRFASSSSVQQITSNHGT-------------------
---DAQPLLLPYKPSGSPKMYYVPRLQRVPPVL--DSKSDTTIESSHSGSNDAVAPVFPA
QVLGTRDDDLP--------------------------------------STVNIKHKEGI
YSKRAVTKASLS---VGKKTSQKDKSEASVQVTIIGDENLSDKKQKEDIFSQRVMTKTAW
PEEKESLQKVTAGSSDAAPAADSAQVQDTKTESIPDTKAT---KQNEI--HIKGTSP--K
EAWTEEKESLHIDISESECHSEFENTTHSVLRSAKFYFHHPVHLPSDQDTCHESLGKN--
---VLMEQSWKDFFQHHSDKHKEHTCLSPPYQNMDK-------TNTDYTRI-KSLSINVN
LGDK----EVIHTTKSQ-GKDRPKSTVQISDS--QKNCKITSELTTQHTVSLNELWNQYQ
ERQRQQKPPG-----VRDRTELSLVERLDRLAKLLQNPITHSLQA-SESMQDDSRGEQNI
KE-WNGKQQQPKSKLQK-KRYKSPEK-GHKNIGDLKKHKVLS----------DHQTGVPN
QIKIEQFKFDKYILKRQPCFNY-ISSTSSDSRP-SEE-SGLLTDTPTNILSTTT-SVDSD
ILTQTDREVAL-HERSSSISTIDTARLIQAFGHERVCLSPRRTKLYSSITNQQRRYLEKR
CKHNKKAFNTGHPQMTSEHTRSRHIQVAHNI-SSDSV-SSASSFLSLSSTLCSENNGYML
NKGIQ-AGNLEIVTGA-KKHTRDVGVTFPTPSSSEARLEEDSDV---------------T
S-SSEEKIEEKQLFTDYFEDKKLRKNKPNSYEGVSWFVPVENVKSRSKKENVP-KIYGPG
VSWFEPVTKTKPWREPLREQNCQGQHMDGQG----SVAGRGGDDGRDPLRPFVKATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLENMLQSERDALFNT----------MRRLPRRV
FLAAQK-KPIGKKEMIQRSKRI-YEQLPEVQKKREEEKRRSEYKSYRLRAQLYKKKVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEEEEAAVAAA-----------------------TVEEAAANLD
DVVVVEVVEEEAGREL---NPDS-HYEHQHVESTDDE---EDEEAKAWLQAHPGNILPP-
------------PSPSRH----RYSEGERTSLEK-------IVPLTCHVW-QQLLYQGNG
RTQISDTNV---ETAAQQGSGDDQKTESWYYLSQEVD-SSQTLDTSETRFNVRTEDTEVT
DFPSLEEGI-LTQSENQVKELS--GDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFTPD
SLFHQSELSFAPLREIPDKSEDTEWFSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTAVGSQCPFLSSEQGKNEETIL--SVDELKIPKDGDSYD-AVCLYMSWKTQKDTQQP
ETNLADRDQVSVATSSDITDENIATKRSDHFDAACSYGQYWKQKALPKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-EFDVITLDG------LNENIV-CSER---VAEL-------------------------
------------------------------------------------------------
--------------------------QRKPRRESEYHSSDLRMLRMSPDTVPKTPKHL-A
GDTSKGS----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSSSLEDLSQLAVSSPL----ET
TTGQHT-DNLNQKTLADTHLTQETLKVTAVPEPADQKTVTPTVLPSSYSHRGKPSIFYQQ
GLPGSHLTEEALKVSAAPGPADQTTGIPTVTST---HREKPSVFDQRELPESNLTEEPLK
VSATPSPVEQKTGIPTVSSTSHSHGENPLFFYRQTLTDGHLTDQALKVSAVSGPADQKTG
TTTALSTPYSHREKPGIFYQPQ--LPDSHQTEETL-KDSSTPGPADQKTEI------PAV
QSSS-YSQKEKPS-ILYPQV-LADSHLPEESMEVSA-VSGPADQKTGLPTVPSSAHSHRE
KLLIFYQ-QALLESHLPKEA-LKISAVS-----GPADEKTGTSAVTSTSSMSSSFAEKPG
AFYQQTLPNSHLTEEALKESVVPGP-DDQKTDLPSTSSSFYSQRQTPIIFSQQILPDTLF
PEEALKVSAVSVLAAQKTGTPTVSSNSPSHREKSSLFYQQELPNSDLRRESLKMSAIPRP
-TDQKT-GTPTVPSGFFPLGEKPSIFSQQELPDSHPTEEALKVS-TGPVPADQKTKIPAV
QSSSYSQRE-KPSVLYPQVLSDSHLPEEGVKVSAF-PGSADQTTDTPAVPSTFYSQR-EK
PGILY------QQTLPDSHLPKEA-LNILVAPRPADLKTGTPTPTSTYYSQHREKPSV-F
HQQALPGTHIPEEARNVSAVTG-PGDQ-KTWIPRVLSAFYSQTEKPGIFYQQTLPGSHIP
EEAQKVSAVP--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------GP-AD-Q--TG-TPT-PTSTSY-SH-TE-KP-GI-FY-QQV--L
PDS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VAPEPVDQTTG-TPT----VTPPSYLQHRENPRIFYQQLLPSSLLTEEAK
NV------SVVPGQADQKT-GIPTLPSTFYSHTEKPGI---FY-QQ-V-LP-HS-H----
LPEDALKVSVAPGP-VD-QTTGTPTIT-SPSNSFGEKP-IVIYKQAFPDGHLPEESLKVS
VAPG-PVGQTTGTPTVTSSFYSQHRVKPSSFYQPPLLGSQIPEEALRVSS-ASGPADHTT
GIPTI----TSPSYSFGEKPIIIYKQAFPDGPIPEEALKALVVSG--------LT----E
QKTKVATGPL--GSSALGEKPITFYQQALPDRPLNQEVVKVSATPGPADQKTETL-PVYS
ITYSHRAKPVIFYEQT-LSDSHLSEEALKVPPVPR-SDAQKTGTPSVSSSLYSHSEKPIV
LYQ-QALRDGQLTKEALKVSAVPHP-ADQ-TGLSTVTSSYYSHTEKP--NISYR-DLPDS
HLTEKALKVSNVPGSADQKTGVSTVTSTSYSHREKPIISYQQELP--HFTEAALGILRVS
EPADQKTGI---NILSSNSYPQREQSVISYQQELPG--LTEVTLKAV---EVPGPAD-QK
TGIQILSSSSYSNREKPSVFHQQELPD--VTEEALNAFVFPGQGDQKT-DIPTVSSNYYS
YGEKPSVSSQ--------------------------------------YELP--DSHLTE
EALKASPVSIPAEQK-TGIPIGLSSSYSHSHTEKLKISTADVPDDQKTEFPAAALSSYPQ
IEKSKISTVIGPDDQKTPSLTVFHSSYSQRVKPDVLFQQQLPDKDQSKGSLKIS-AVPEP
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRYVTEDVLKVSAIPGSAGQKTV
LPTAPSSSFSHQEKPDIFYHKDLPDRHLTEDALKISSALGQADQITRLQAVPSGTDSHG-
---EKHKLI-SEH-VQRLIDNLNSS-G---SSFSTNN--VLLN-SQADD--RVVINKPES
AGFR----DVGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLT
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NVELL-QRQAF---TDESSS-SRCIQK
DIGTQ--TNLKCQRGI-ENWKFISSTTV--RSPLQEAENK-ASMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TIIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITE--SREEEGVSESEDGGGSSIDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGFQSPRGMGCKPEAVCSHIIIQSHEKGCFRTLTS-EQPQLDSHPCV-FR
SAEPSEMTRG-RQSPSSCRARHVNLSA-RLDQNNSHFKVWNSLQLKNHSPFQNFIPDEFK
ISKGLRMPFH---EKKDPWLSELV-----EPAFVLP---KEVDFHSSSQMPSPEPMK--N
VTTSITFSSHRHSKGISDS--SVVKVGVTEG-SQCTGASVGIFNSHFTEDQNPPRDLKQK
TSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLSVDFEHSLQEEKPLERSDFTGSHCEPS
TTADCSNVKEIQISDNH-TLISRGRPSSTLGVSRSSSRLGVKEKNVTITPDLPSCIFLEQ
RELF--EQSKAPHADHHVRKHQSPSSQHQDYVAPDLPSCIFL--EQRELFEQCKVPHV--
-DHQMREKHSPLPQGQDSVASDLPSPISLEQC----QS-KAPGVDDQMRKHHFPLPQGQD
CVVEKNN-QHKPKSHIS-TINVEAKFNNVVSQSAPNHYTLTTS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRFYSLDAASKARINSEFNFDLPT----ISSRSLEPTSKLLTS
KPVAQDQESLGFLGPKSSLDFQAVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSYPE--GTPVSADRLPEKKK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INPEDRGHEITEPSNQ-KLRKASVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSS--DSISDTTVESSHSGSNDAVAPDFPA
QVLGTRDDDVS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGGKPLRNDSADASVQVLITGDVNLSDKKPK-ESHSMSAVTEAAQ
AKEKEPLQKDTADSSDAAAAEHSAQVGDPKIKNSPDSKAI---TQKEEI-HRKMTIP--E
EAWPKDKESLQINIEESECHSEFENTTHSVFRSSKFYIHHPVHLPSDQDVCHESLGRS--
---VFMRHSWKDFFQHHPDKHREHICFPLPYQNMDK-------TKPDYTKI-KSLSINVN
LGNK----EVMHTTKSQ-ATDYPKYNVQINDP--KRDQKLTPGQAAQHTVSLNELWNKYR
ERQRQQMQPK-----LGDRKELSLVERLDRLAKLLQNPITHSLQV-SESTHDDGRGERGV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SLKNTEELKKSKVFS----------HHGAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTCHPQMTSEHTRRRRIQVANHVISSDSISSSVSSFLSSNSTLCNKQNVHML
NKGIQ-AGNLEIVNGV-KKHTRDVGMTFPTPSSSEAKLEEDSDV---------------T
S-WSEEKHEEKTLFTAYPMDRKLKRNKKISHEGVSWFVPVEN-ESGSKKENMP-KMCGPG
VSWFEPLTKTKPWREPLREQNWQGQHLNGRG----SLAGPGREDGRDALKPFVRATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLQSMLQSERDALFNIDREQQSHQNCMRSLPKRV
FLAAQKNKPISKKEMIQRSKRI-YEQLPEVQKKKEEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPDELEEEEE-EEEEEGEEEEGKKEV--------ENASAAATEEAL---TSEE
SGRLEEFE--EAGP-----DLDF-NYESQRQESSD---EEEDELAKAWLQAHPDRPGSAF
SLPPPTPPPPPPPLSPRL----RYTPVEHLGKTE-------VVPLTCRVW-QQSSYQDNS
RAQFSNSSTMLLETGVRWGSEEDQRTESWHCLPQERD-SSQTLAMSQTEIG-RVEGTEVP
DLPSQEGGL-PAQSQCPGKKPK--LNVLCSPLLVIQDNFAAPDLPLLTCLIQDQEEVEPD
SLFQQSELEFAPLRGIPDKSEDSEWLARPSEVSEALIQATSETSSDLANSCFSISQHPL-
T-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------EGLQGK
A-ESGVLTRCGDAKYSSLYENLGAQSER---IAVLQ------------------------
------------------------------------------------------------
----REVGCSNLGISQASPSSLPSFVPQEPTSEPEYHSSNLRMLRVSPDTLLTTHT--H-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SAGSADQKIG
A-AVVSSAYSQEIKPGSFHQEE--LPDRHLNEEIR-KVSPALRTAGQKPEM------LPV
QSSS-YSKGMK-S-IFYQHP-VSHGHQGKEPLSVSA-VCGSAGNK---------------
---AFHQL----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------STLSDSLLTEETWPVS-VIPGLGNQKTPLPSE
FSLSYSHRGKNL------------------------------------------------
--------------------PEDV-VKVSTDSGSAHKKADILTA-SSRTYQHKMKPA-NI
YHQELPDSRVPIGTRKVAFESG-PAGQ-KSGV----------------------------
-------------------------S-------HP-YG-EM-PS-VF-YQ-QGL-PD-RH
-SAK-SPTK---------------------------------------------------
------------------------------------------------------------
-----------T-FIPGP-AD-QK-TD-LSP-VPPTSS-SH-AE-KP-VS-PY-QLT-L-
PGS------------------------------------------------HLPED-V-F
K-ASSV--CKSS-DE-L-SG-ITA-LT-SASYS---------------------------
------------------------------------------------------------
-------------------------------YKGRP-N-S-SY-QQ-K-FP-DS-H----
LNEEAQKILGTTGT-VD-QKT-VTPTMSSS-FLQKEKP-SIFYQQTLPDGGLSEEDLQVS
AVPW-PADQNIAIPTVTSAAF-SQREKPRIFYQQTLSVDRLPGEPLNVLG-TSGPPDQNT
GAPTV----TPSSYFPGEESIIFYQAGFPGNTLSAMSFKVPRISG--------ST----E
QTNVT-TGSS--SSYSVGEKSIIFYHQALPDGRLPQEA-----SPAPADLNTGEP-PMYL
ASCSVGVKPIIFYQQP-MSDSQRTK-GHKESDVPG-PTDQKTGIATVHSTSQSYIGRRTV
SYQ-KEFPDL--SEKALKVLGDVGS-TEQKTQIPVVSSALL-HKEGP--SA-YQEDLPD-
-LTEEPLQILGVSEE---------VSS----------SSYQRKLPD--HIEVFLKSVG-S
GSADRKTGA---QIV---SS-SREKSSGFHQQE--LPNTGGDAVDAF----HPEPVV-QE
VRKV-----------------------------------------QTP-GAPAGPSSSHF
HKEKLSD-YQ--------------------------------------KASPHR--DLTE
SSLKASTVPGLSDQK--KKPAVSSGFCLH--KEKHEISASALLNCQTAELLTVTQRSCLH
REDPAISTVIKPDDQKIPLPTTFHGSSDQKVKPVIFVQKQLRDRDQSEDIPKIS-TVSEP
TVVN-----TVLPVLLPGSYSHREKSDS--FYPQELPDGHL-------------------
----------------------------TEVDLKVSSGLGQADQISGLPTGIPGTYSHS-
---EKHQLI-SEH-VQELMDNLNSS-ES--SCLSVDS--MPLNSQIDDG---VIICKPES
LGFA----NAGC---EEMQNIDR--GSKT-LKEIQTLL-ME-AENMALKRCNFSV--PLV
PFRDVND-V--SFIRSKKVVCFKESSTTDVC-------TQRESF---VEEVPH-IEYVQK
DIGTQ--TNLKYQRGV-GNWEFISSATF--RSPLQEAEGT-ARMAYD-ETFRQYKAA-RS
VMR-SEPEGC-STGIGN-KMIIPMM-TIIKSDSS-SDVS---DGCCSWDNNLP----ESL
ESVSD-VFLNF-FPYTSPKTS-ITD--SREEEWLSESEDGYG-STDSLAAHVKYLLQCET
SLNQAKQILKNAEEEEYRVRT--QAWNLKFNLGRD--RGYSISELNEDDRRKVEEIKAKL
FGHGRATHMSEGLRSPQGIGCLPEAVCSRIIIESHEKGCFRTLTA-EQPRPDSCHCA-FR
SVEPSDLIRG-HRSPSSWRGRHINLSR-SIEQSNPCFKVGSSFQLQSHPPFQKLLPDDIK
ISKGVGMPVH---AYMDPQPSELV-----EPTCVPA---KEMDFPSSSQILPPEPKK--Q
FTTAITFSSHEHSECISDS--SGCKVGVTAD-SQCSGPSLGVFKPHIPEEQISPRDLKQK
TSFQSSLERHGSTP-----VTILADGSRQRQKLPVDFEHSHQKEKLLQRLGFKVSHSEPN
VSTNVSNFKGVQFSGKD-TIVSQDKLTSTV---------EVKEKNVTVTPDLPSCIFLEQ
PELF--EESHTPHTDLQMRKYPSPS-------CPEIASRIFL--EQPKLSEQSKAPHVD-
--REIREDHSFFPKCQDYIVAD-PSPDFPDQQ----QC-KPPDVVGHTRKQNSLLSEGQD
YELEE-V-QHIPQSYFSNMVNVEAKVSDAISQSAPDHCTA-----ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLGERFHSLDPASKTRINSEFNSDLRI----ISSRSLEPTSKLLTC
KPVAQDQESLVFLGPKSPLDLQVAQSSLPDS-KTIFQDLKTKPPQNSQIVTSRQTQVNIS
HLEGYSKPE--GTPVSADGSQEQSK-VSFTTSFGKLS-SDAITQITTESPEKTTFSSEIF
IHADDRGQGILDPMAQ-----KPSRFASSSSVQQIPASHGK-------------------
---DAQPVLLPYKPSGSSKMYYVPLLKRVPSYL--DSKSDTTVESSHSGSNDAIAPDFPP
QMLGTRDDDLS--------------------------------------NTVNIKHKEGI
YSKRAATK--------GKNPSQKGDAAAPVQMPITWDENVLDENQE-EVISRGVVIKMAG
PEEMSSLEKDLAGPSD-------ITVQDRKTENLPDTKSI---KQKEGS-----------
---------L---EIESECHSAFENTAHSVFRSAKFYFHHPVHLPHEQDFCHESLGRS--
---VFMQHSWKDFFHHHS----GHSCLPPPGPSSDK----LDKTKMDYTRI-KSLSINLN
LGEH----EKIHTIKNQ-ARDPKG-KRQANEQ--KKDQKVTPELTTECPVSLNELWNRYQ
ERQKQQNPSG-----ACDTKELSLVERLDRLAKLLQNPITHSLRA-SESAQDDSRGGHRA
RE-WTGRRQQKQKGKQHRKWSKSLER--GQSTGDFRKSKVFS----------PHQGGKSS
QFKIEQIKLDKYILRKEPGFNN-VSNTSLDSRP-SEE-SV-SLTDSPNIFSSTDSPVDSD
VLTPTDRDMPL-NERSSSISTIDTVRLIQAFGQDRLSLSPRRIKLYSTVTSQRRRYLEQP
CKHNRKALNTACPQMTSEHSRRRHIQVANHMTSSDSV-SSPGSLLSLDSALSNEETVRMV
SKGVQ-AGNLEIVAGV-KKYTQDVGVTFPTPSSSEARLEEDSDV---------------T
S-SSEEKAKEKKFLSNYLQTKNLRKNKPNPCAGVSWFVPVESGQSGSKKENLP-KIYRPV
ISWFEPVTKTKPWREPLREQNWQAQCMNSRG----SLGGPGRDSGQVSLRPFVRATLQES
LQLHRPDFISHSGERIKRLKLLVQERKLQSLFQSEREALFHS----------ARPLPRRV
LLAVQKNKPIGKKEMIQRTRRI-YEQLPEVKKKREEEKRKSEYKSYWLRAQHYKMKVTNH
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEEEEEEEEEEEEEDE----------------EEEEEEEEAAAA
NLDAVVVVEEEAGREL---NSDS-HYEHQHVESTDDE---EDEEAKAWLQAHPGKILPP-
------------PSPSRH----RYWEGERTSLEK-------IVPLTCHVW-QQLLYQG-G
RTQISDTNV---ETAVQQGSGDDQKTESWYYLSQEVD-SSQTLDTSETRFNVRTEDTEVT
DFPSLEEGI-LTQSENQVKELN--RDLFCSPLLVIQDSFASPHLPLLTCLTQDQ-EFTPD
SLFHQSELSFAPLREIPDKSEDTEWFSQLSEVSEVLFQATAEVASDLASSCFSISQHQL-
IDSTAGGSQCSFLPSEQGNNEETIL--SVDELKIPKDCDSYD-ALCLYMSWKTQIDTQQP
ETNLADKDQVSVLTSSDITDENIATKRSDHFDAACSYGRYWKQKASPKQGET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDVITLDGDAECCSLNENIV-CSER---IAEL-------------------------
------------------------------------------------------------
--------------------------QRKPTGESEYHSSDLRMLRMSPDTVPKTPKHL-A
G-----S----------------------IAKVTQS------------TLKPDI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLAVSSPL----ET
TSGQHT-DTLNQKTLADTHLTEETLKVTAVPEPADQKTATPTVLSSSYSKKGKPSIFYQQ
GLPDSHLTEEVLKVSAAPGPADQTTGIPTVTST---YREKPGVFDQQELPESNLIEEPLK
VSATPSPVEQKTGIPTVSSTSHSHEENPLLFYRQTLTDGHLTDEALKVSAVSGPADQKTG
TATVLSTPYSYREKPGIFYQPQ--LPESHQTEETL-RDSATPGPADQNTEI------PAV
QSSS-YSQRKKPS-ILYPQV-LADSHLPEEGLDISA-VSGPADQKTGLPTVPSSAYSHRE
KFLISYQ-EALLDSHLPKEA-LKISAVS-----GLADEKTGASTVTSTYSMS-SLAEKPG
AFYQQTLPNSHLTEEALKVSIVPGP-DDQKTGLPSTPSSFYSQTQTPIIFSQHTLPDILF
PEEALKVSAVSVLAAQKTGTPTVSSNSPSHREKSSIFYQQELPNSDLHRESLKMSTIPGL
-TDQKT-GTPTVPSGFFSLGEKPSIFSQQELPDSHPTEKALKVS-TGPVPADQKTKIPAV
RSNSYSQRE-KPSVLYPQVLPDSHLPEEGLKVSAF-PGPADQTTDTPAAPSTFYSQR-EK
PGIFY------QQTLPDSHLPKEA-LNILVAPRPADLKAGTPTPTSTYFSQHREKPSI-F
HQQALPGSHIPEETQK--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------VS-AVPGQ-AD-Q--TG-TPT-PTSTSY-SH-TE-KP-GI-FY-QQV--L
PDS---------------------------------------------------------
------------------------------------------------------HPAEEA
LKIS------VAPEPVEQITG-TPT----VTSPSYLQHREKPRIFYQPLLPSSPLTEEAK
NI------SVVPGQADQKT-EIPTLPSTFYSHTEKPGI---FY-QQ-V-LP-HS-H----
LPEETLKVSVAPGP-VD-QTTGTPTVT-SPSNSFGEKP-IVIYKQAFPDGHLPEESLKVS
VAPG-PVDQTTGTPTVTSPFYSQRRVKPSSFYQLPLLDSQIPEEALRVSS-ASGPADHTT
GIPTI----TSPSYSFGEKPIVIHKQAFPDGPIPEEALKVSVVSG--------LI----E
QKTEIPTGPL--ASSALGEKPITFYQQALPDSPLNEEVVKVSATPGPGDQKTETP-PVYS
ITYSHRGKPVIFYEQT-LSDSHLSEEALKVPPVPR-PDAQKTGTPSVSSSLYSHREKPIV
FYQ-QALRDSQLTKEALKVSAVPRP-ADQ-TGLSTITSSYYSHTEKP--NISYQ-ELPDS
HLTEKALKVSNVPGSADEKTGVSTATSTSYSHREEPIISYQQELP--HFTEGALGILRVS
EPADQKTGI---NTLSSNSYPQREQSVISYQQELPD--LTEVTSKAV---EVPGPAD-QK
TEIQILSSSSYSNREKPSVFHQQELPD--VTEEALNVFVFPGQGDQKT-DIPTVSSSYYS
YGEKPSVSSQ--------------------------------------YELP--DSHLTE
EALKVLPVSIPAEQK-TEIPIGLSSSYSHSHTEKLKISTADISDDQKTEFSATALSSYPQ
IEKSKISTVIGPDDQKTPSLTAFHSSYSQRGKPEILFQQQLPDKDQSKVSLKIS-AVPEP
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRYVTEDVLKVSAIPRPAGQKTV
LPTAPFSSLSHQEKPDI-YHKDLPDRHLTEDALKISSALGQADQITRSQTVPSCTHAHG-
---EKHKLI-SEH-VQRLIDNLNSS-G---SSFSSNN--VLLN-SQADD--RVVINKPES
AGFR----DVGP---EEIQDAES--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDLS--NVELL-QRQAF---TEESPS-SRCIQK
DTGTQ--TNLKCQRGI-ENWEFISSTTV--GSPLQEAENK-ASMALE-ETHRQYQAA-KS
VMR-AEPEGC-SGTIGN-KIIIPMM-TIIKSNSS-SDTSD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGSSSIDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEF
FGHGRTTDLSKGLQSPQGMGCKPEAVCSHIIIQCHEKGCFRTLSS-EQPQLDSHPCV-SR
SAEPSEMTRG-RQSPSSCRARHVNLSA-SLDQNNSHFKVWNSLQLKSDSPFQNFIPDEFK
ISKGLQMPFH---EKMDPWLSELV-----EPAFVPP---KEVNFHSSSQMPSPEPMK--N
ITTSITFSSHRHSKDISDS--S---VGVTEG-SQCTGASVGIFNSHFTEDQNPPRDLKQK
TSSPSSFKMHSKSPDK--EVTILAECRRQSQKLSVDFEHSLQEEKPLERSYFTGSHCEPS
TTADSSNVKEIQISDNH-TLISRGRPSSTLGVSRSSSRLGVKEKNVTITPDLPSCIFLEQ
RELF--EQSKAPRADHHVRKHHSTSPQHQDYIAPDLPSCIFL--EQRELFEQCEVPRV--
-DHQMREKHSPLPQGHDSVASDLPSPISLEQC----QS-KTPGVDDQMRKHHSPLPQGQD
CIVEKNN-QHKPKSHIS-TINVEAKFNNV-SQSDPNHYRLPTS--AST-PSNRKALSCVR
ITLCPKTSSKLDSGTLDKRFYSLDAASKARINSELNFDLPT----ISSRSLEPISKLLTS
KPVAQDQESLGFLGPKSSLDFQVIQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIEVNIS
DFEGHSNPE--GTPVSADRLPEKKK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INPEDHVHEITEPSNQ-KLRKASVKFASSSSVQQVTFSHGT-------------------
---DGQPLLLPYKPSGSMKMYYVPQLRQIPPSL--DSKSDTTVESSHSGSNDAIAPDFPA
QVLGTRDDDVS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---LGGKPLRSDSADASVQVLITGDENLSDKKLK-ESHSTSAVTEAAQ
AKEKEPLQKDTADSSDAAAAEHSAQVGDPKIKSFPDSKAI---TQKEEI-HRKRTIT--E
ETWPKDKESLQINIEESECHSKFENTTHSVFRSAKFYIHHPVHQPSDQDVCHESLGRS--
---VFMRHSWKDFFQHHPDKHREHICLPLPYQNMDK-------TKMDYTKI-KSLSINVN
LGNK----EVIHTTKSQ-ATDYPKYNVQINDP--KRDQKLTPEQTTQHNVGLNELWNKYR
ERQRQQRQPK-----LGDRKELSLVERLDRLAKLLQNPITHSLQV-SESTRDDGRGERRM
KE-WSGRQQQ-RNKLQKKKQFKSLEK-SHKNTGELKKSKVFS----------HHGAGRSN
QIKIEQIKFDKYILSKQPGFDY-ISNTSSDCRP-SEE-SELLTDTTTTILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGRERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLTTCHPQMTSEHTRRRRIQVENHVISSDSISSSVSSFLSSNSTLCNKQNVHML
NKGIQ-AGNLEIVNGA-KKNTRDVGMTFPTPSSSEAKLEDDSDV---------------T
S-WSEEKHEEKMLFTTYPVDRKLKRNKENSHEGVSWFVPVENVESGSKKENMP-KMCGPG
VSWFEPLTKTKPWREPLREQNWQGQHLDGRG----SLAGPRREDGRDTLKPFVRATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLQSMLQSERDALFNIDREQQSHQNCMRPLPKRV
FLAAQKNKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWN---------------------------------------

MEPEDLPWPDELEEEE--EEEEEGEEEEGKDEV--------ENALAAATEEAL---TSEE
SGRLEEFE--EAGP-----DLDY-NCESQLQESTD---EEEDELAKAWLQAHPDRPASAF
SPAPPTPP--PPPLSPRH----RYTPVEHLGKTE-------VVPLTYHVW-QQSSYQDNS
RAQFSNSSTMLLETGVQWSSEEDQRTESWHCLPQERD-SSQTLDMSQTEID-RVERTEVT
DLPSQEGDE-SAQSQRPVKKPK--LNLLCSPLLVIQDNFAAPDLPLLTCLIQDQEEVEPD
SLFQQSELEFAPLRGIPDKSEDTEWLARPSEVSEALIQATSETSSDLANSCFSISQHPL-
T-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------EGLQGK
A-ESGILTLCGDAKYSSLYESAGAHSER---IAELQ------------------------
------------------------------------------------------------
----REVDCSNLGISQASPSSLPSFIPQEPTSESEYHSSNLRMLRVSPDTLVTTHT--H-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------STGSVDQKTG
A-AVVSSAYSQEIKPGRFHQEE--LPDRHLNEGVR-KVSPALRTAVQKPEM------LPV
QSSS-YSKGMK-S-IFYQHP-VSHRHQGKEPLNVSA-VSGSADNK---------------
---AFYQQ----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------TLSDSLLTEETLPVS-VIPGPGDQKTPLPSE
FSLSYSHRGKNL------------------------------------------------
--------------------PEDV--KVSTDSGSAHKKADIPTA-SSSTYQHKTKPG-NI
CHQELPDSRVPIGSRKVAFESG-PAGQ-KSGV----------------------------
-------------------------S-------HP-YD-EM-PS-VF-YQ-QEL-SD-SH
-SAK-GPTK---------------------------------------------------
------------------------------------------------------------
-----------T-FIPGP-AD-QK-TD-LTT-VLPTSS-SH-AE-KP-VS-PY-QLT-L-
PGS------------------------------------------------HLPED-V-F
K-ASSV--CKSF-DK-L-SG-ITA-LT-SASSS---------------------------
------------------------------------------------------------
-------------------------------YKGRP-N-I-SN-QQ-K-FP-DS-H----
LIEEAQKILGTTGT-VD-QKT-VTPTMSSTFFLQREKP-SIFYQQTLPDGGLSEEDLQVS
AVPW-PVNQNIAIPTVTSASF-SQREKPQIFYQQTLSVDHLPGEPLNVLA-ASGPPDQNT
GAPTV----TPSSYFPGEESIIFYQAGFPGNTLSAMSFKVPRISG--------ST----E
QTNIT-TGSS--GSYSVGEKSIIFYHQALPDGHLPKEA-----SPAPADLKTGEP-PIYL
ASCSVGGKPIIFYQQP-MSDSQLTK-GHKESVVPG-PTDQKTGIPTVHSTSQSYIERRTV
SHP-QEFPDL--SEKALKVLGDVGS-TELKTQIPVVSSALL-YKEGP--SA-YHEDLPD-
-LTEEALQILGVPEE---------VPS----------ISYQKKLPD--HTEVSLKSVG-S
GSAHQKTGA---QIV---FS-RREKSSGFHQQE--LPNTGGDALDVF----HPEPVV-QK
VRKATEPSSYYPQG-EASALSPQELPASHLTGEALKVSDGSALAAQTP-GTPAGPSSSHF
HKEKLSD-YQ--------------------------------------KASPDR--DLTE
SSLKASTVPGLSDQK--KRPAVSTGSCLH--KEKHKISASDLLDCQTAELPTVTQRSCLH
REDPAISSVIKPDDQKIPLSTTFHGSCAQKVKPVIFIQKQLRDRDQSEDIPKIS-TVSEP
TVVN-----TVVPVLLSGSHSHREKSDS--FYPQELPDRHL-------------------
----------------------------TEVDLKVSSGLGQADQISGLPTGIPGTYSHS-
---EKHQLI-SEH-VQELMDNLNSS-ES--SCLSVDS--MPLNSHIDDG---VIICKPES
LGFA----NVGY---EEIQDIDH--GSKT-LKEIQTLL-ME-AENMALKRCNFSA--PLV
PFRDVND-V--SFIQSKKMVCFKESSTPDVC-------TQRESF---VEEVPH-IEYVQK
DIGTQ--TNLKYQRGV-GNWEFISSATF--RSPLQEAEGT-ARVAYD-ETFRQYKAA-RS
VMR-SEPEGC-STGIGN-KIIIPMM-TIIKSDTS-SDVS---DGCCSWDNNLP----ESL
QSVSD-VFLNF-FPYTSPKTS-ITD--SREEEWLSESEDGYG-STDSLAAHVKYLLQCET
SLNQAKQILKNAEEEEYRVRT--QAWNLKFNLGRD--RGYSISELNEDDRRKVEEIKAKL
FGHGRATHMSEGLRSPRGIDCLPEAVCSRIIIESHEKGCFRTLTA-EQPRPDSHHCA-FR
SVDPSDLIRG-HWSPSSWRGRHINLSK-SIEQSNPRFKVGNSFQLQSHPPFQKLLPDDIK
ISKGVGMPVH---AYMDPQPSELV-----EPICVPA---KEIDFPSSSQILPPEPKK--Q
LTTSITFPSHEHSKCISDS--SGCKVGVTAG-SQCTGSSLGVSKPHIPEEQISSRDLKQK
TSFQLSLERHGSTP-----VTILADGSRQRQKLPVDFEHSHQKEKLLQRSGFKVSHSEPN
VSTNVSNFKGVQFSGKD-TIFSQDKLTSTV---------EVKEKTITVTPDISSCIFLEQ
QELF--EGSHTPHTDLHMRKHTSPS-------CPEIASCIFL--EQPKPCEQSKAPHVD-
--YEVREDHSFFPKCQDYIVAD-PSPDFPDQQ----QC-KPPDVDGHTRKQNYLLSQVQD
YGVEE-V-PHIPQSYFSNMVNVEAKVSDTISQSAPDHCTA-----TSTPPSNRKALSCVR
ITLCPKTPSKLDSGTLDERFHSLDPASKTRINSEFNSDLRI----ISSRSLEPTSKLLTC
KPVAQDQESLVFLGPKSLLDLQVAQSSLPDS-KTIFQDLKTKSPQNSQIVTSRQTQVNIS
NLEGYSKRE--GTPVSADGSQEQSK-VSFTTSFGKLSSSDAITQITTESPEKTTFSSEIF
INADDHGQGTLDPMAQ-----KPSRFASSSSEQQIPASHGK-------------------
---DAQPVLLPYKPSGSSKMYYVPLLKRVPSYL--DSKSDTTVESSHSGSNDAIAPDFPP
QMLGTRDDGLS--------------------------------------NTVNIKHKEGI
YSKRVATK--------GEKHSQKDNTAAPVQMPITWDEKVLDENQE-EVLGRGVVIKMAG
PEEMSSLEKDLAGPSD-------ITVQDRKTENLPDTKSI---KQKEGS-----------
---------L---EIESECHSSFENTTHSVFRSAKFYFHHPVHLPHEQDFCHESLGRS--
---VFMQHSWKDFFHHHS----GHSCLPPPGPSSDK----LDKTKMDYTRI-KNISINLN
LGDH----EKINTIKNQ-ARDPKG-KRQANDQ--KKDQKVTPELTTECPARLNELWNRYQ
ERQKQQKPSG-----ACDTKELSLVERLDRLAKLLQNPITHSLRA-SESTQDDSRGEHGA
RG-WTGRRQHQQKGKQHRKWSKSLER--GQSTGDFRKSKVFS----------PHQGGKSS
QFKIEQIKLDKYILRKEPDVNN-VSNTSLDSKP-SEE-SE-LLTDSPNIFSSTDSPADSD
VLTPTDRDISL-NERSSSISTIDTVRLIQAFGHDRLCLSPRRIKLYSSVTSQRRRYLEKP
CKHNRKALNIACPQMTSEHTRRRHIQVANHMTS-DSV-STAGSLVSLDSALSSEETVLMV
SKGVQ-AGNLEIVAGV-KKYTQDVGVTFPTPSSSGARLEEDSDV---------------A
S-SSEEKPKEKKFLSNYLQGKNLRKNKPSPCEGVSWFVPVENGKSGSKKENLP-KIYRPG
ISWFEPVTKTKPWREPLREQNWQAQCMSDRG----SLGGPGRDSGQVSLRPFVRATLQES
LQLHRPDFISRSGERIKRLKFLVQERKLQNLFQNEREALFNS----------VRPLPRRV
LLAVQKNKPIGKKEMIQRTRRI-YEQLPEVKKKREEEKRKSEYKSYRLRAQHYKMKVTNH
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEEEAAAAAKA-----------------T------NS----DAA
--EAVGE-VGEEAGKL---DSDF-NYGYHHLESTDD--DDEDEEAKAWLQAHPGGPLPP-
-----------PSPSAKY----GYSEGEQPSPGK-------VVPLNCYVW-QQSFHQGSS
RTQITNTNA--PETTAQWGSGDDQRIESWHCLPQEMD-SSLTLATPQTEFSATAEGTEVT
DFPSVEEGV-LTQSENQVKAPT--RNLLCSPLLVIQDSFASPDLPLLTCPSQDQ-EFGSD
SLFHQSELGFAPLRGIPDRSEDTEWLSRPSEVSEALFQATSEVTSDLSNSCFSVSQHTL-
RGSTAVGSQRSL----QGNNEEAISSGTVDELKTPNVSDSYG-APSSYMSWKTQKDTQQP
EINLTDKDEVSISTSSDITDGNIDTKRSSNFDASCSHSQYWTQGVLQ-PEETYLIKGLQG
KTE--SDVI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------TPAAAAERYSLYENVVGGE-----R----------------------------
----------------------------------------------------A-------
------------------------EVPRKPTRGSEYHSSTLRMLRVSPDALPKTLQHLT-
GDTTKGG----------------------IAEITQS------------NLKSGIT-----
----TTPG--------------------DSDTL--SHLSLSPEDLSQSAVSSPQD----N
TIGQHT-DTLKQKTLAD-------------------------------------------
---------------------------------------------------THL------
-----------------------------------------TEETLKVSAIPEPTDQKTR
TPTVPSSSYSHRGKPNIFYRQG--LPDSHLTEEAL-KVLGVPGPADQKTGI------PTI
TSTS-HSHRGKPV-IFYQQG-LTGSPIPEEALKVSA-VSGPADQKTRIAPVPSTPYSHRE
RPGTFYQQELLDIKQTEEAPKICLVKMP-----GFSLSEL--------------------
-------------------------------------------QLVVCQFYGQQVQVQLK
L-------SDPLW--VDDYLPRSG----------GRKYQASLYLS---RE---VLVLSGS
-S-EGT-GAVRVFWSAG-------------------------------------------
------------------------------------------------------------
--QNC------KKLSIDSHLPKED-QKVLAAPGPADHKTGIPPTVISTSYSDREKPGI-F
YQQALAGSHIPEEALRVSFVPG-PVDQ-TTGIATVTSTS---------------------
-------------------------K-------SQ-HR-EK-PG-VF-YQ-QDL-PG-SH
-LAE-EAQ-KVLVV----------------------------------------------
------------------------------------------------------------
---------------SGP-AD-QT-SG-IPT-VTSTSY-SH-RE-KP-GI-FY-QQV-L-
PGS------------------------------------------------HIPKE-T-L
R-VPFA--PSPA-DQ-K-TG-RPT-VT-SASNL---------------------------
------------------------------------------------------------
-------------------------------HREKP-I-I-FY-QE-A-LP-DT-H----
LPEKAQKVSPSLGS-AD-QKTDIPTAA-SPSYSPIEKP-IIFYQQTLSDSHPTEEAQKVS
FVSG-PADQKTGIPTVTSTPY-PQREKLGIFYQQGLPGSHLTEEALKVSA-VPESTDQKT
GTPTV----SPTSYSLGDKSIIFYPQVLPDSHLTEEALKVSVVSG--------PA----D
QKTGIPTVSP--VSYSLGEKPIIFYQQTLSDSQLSKESLKVLGVAGPVDQKTGIP-PVTY
SSYSQREKPIISYQQE-LPDSLLTKKALKVSNVPE-PAGQKTGIP---------------
----------------------------------TVTSTSYSHRERP--GVSYQQDLPE-
-FDEEALILSGIASGVDQRNVIRIVPSGSYSHNGKPIISYQQELPN--YTEEALKVLVVP
GTADQKTGI---QIVPSTSYSQGEQSIIYQ-QE--LPDLTEVALKSF---GVSGPAD-QK
TEIQKASSSSYSHREKPSIYPQQEFPD---------------------------------
---------------------------------SH----------------------LTD
EALKASAVFVPAEQD-TGIPTGIPNYYSP--QEKLKISAVNALDVQKTELPTTTPSSYSY
EETPRISTVIGPDDQKTPLLTVFRSPYSQRVKPAILLQQQLPDGDQSESILKIS-TVPEP
TDVKPVPLPAGKPVPLSSSSFQREKPTI--FYPQELPDTHLTEDTLKLSTVPGSADQKTV
LPVVSPSSFSLREKSNIFYQKDLPDRHVTEDALKFSGGPGQADQITGLQTVPSDAYSDG-
---EKHKLV-SKH-VQRQINNLNSS-D---SSVSSNN--MPLN-SQADG--KVVINKPES
AGLV----DVGS---EEIRDAEN--SSKT-LKEIQTLL-ME-AENIALKRCNFPA--PLV
PFRDVGD-I--SFVQSKKVVCFKEPSMTDVC--NGDLLQ-RQPY---TEESPN-NRCMQK
DIGTQ--TNLKCQKGI-ENWEFISATTV--RSPLQEAECK-ASMALE-ETLRKYEAA-KS
VMR-SEPEGY-NRTIGN-KIIIPMM-TIIKSDSSS-DISD-GNGSYSWDSNL---PE-SL
ESVSD-VLLNF-FPYVTPKTS-ITD--SREEEGMSESEDGGGSSIDSLAGHVKNLLKCES
SLNHAKQILRNAEEEECRVRA--RAWNMKFNLAHD--YGYSISELNEDDRRKVEEIKSKL
FGHGRTTDLSKDLQSPRGIGCKPEAVCSHIIIESHEKGCFRTLTAAEQSQLDSHTCV-FR
SSDPSEMIRG-RRSPSSWKDGHINLST-SLDQNNPHLKVWNSVQLQSHSPFQEFVSDDFK
ISKGLRMPFH---EKMNAF--------------VPP---KEVDFHSSSQMPPPEPTK--K
FTTSITFSSHRHSKCISDS--SMLKVGVSEG-SQCTGASVGVFNSHFTEEQNPPRDLSQK
TSSPSSFKTHSHSSDK--DVTILAEGSRKSQKLPVNFKHSHKEEKCLERSDFKGSHSEPS
ASANCSNFKEVQFSDNH-TLISMGRPSSTL---------GVKQKNVTITPDIPSSIFLEQ
RELF--EQSRAPHADHHVRKQISRLVP---------------------------------
-----------------EVGASFLSPIFLEQR----QS-KAPCIDNYMKKHHFPFPQGQD
SVVEKND-QHKPKSHASNMISVEAKFSNV-SQSPPDYCTLETS--ASTPPSNRKALSCVR
ITLCPKTPSKLDSGTLDKRFHSLDAASKTRMNSEFNFDLQP----ISSRSLEPTSKLLTS
KPIAQDQECLGFLGHKSTLDFQVVQSSLPDS-NTVTQDLKTIPSQNRQIVTSRQTQVNIS
DLEGYSNPE--GTPISADRSSQKIK-TPCSAFPGKLS-SDAVTQITTESPEKAIFSSQIF
INAEDRGREIPESSSQ-KLNKAPIKFASSSAVQHLTFPRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLGKIPPSM--DSTSDTTIESSHSGSNDAIAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRATSKAFLP---VGKKPLQKDNADASVQVAIIGDEDLSNKKQKEEIISTSEVTKVAQ
PEEKESLQKDTADSSDVTAAEHSAQVQDTKIKDLPDTKAI---KQKEKI-HSKTTVP--M
QAWPEDEKSLQIDIEEAECRSEFENTTHSVFRSAKFYIHHPVHPPSDQD-GQESLGRS--
---VFVRHSWKDFFQHHPGKHREHARLP-SFENADK-------TKTDHARI-KSLSINVN
LANK----EVVHTPKSQ-GKDHPQHNRQISDP--KKDHKVTPELKTPHTVCLNELWNKYK
ERQRQQKPSE-----LSDKKELSLVERLDRLAKILQNPITYSLQA-SESTQDDSRGERGA
KE-WSSRQQQ-RHKLLKKKRYKSLEK-SRKNTGDLKKNKVLS----------THQAGRSN
QIKIEQIKFDKYILRKQPNFNY-ISNTSSDSRP-SEE-SELLTDTPTNILSTT--SVESD
VLTQTDGEVAL-HERSSSISTIDTARLIQAFGHDRVCLSPRRIKLYSSVTNQQRRYLERR
SKHNIKALNTGHPLMTSEHTRR-HIQVAKRVISSDSISSSANSFLSSNSTMCNKQNVRML
NKAIQ-AGNLEIVNGT-KKHTRDVGLTFPTPSSSKARLEEDSDM---------------T
S-WSEEKIEEKVLFTSYPEDKKLKKNKQISYEGVSWFVPVENMKSGSKKENVP-EIFGPG
ISWFEPITKTKPWREPLREQNWQGQRMDCPE----SLADPG----KEPPKPFVRATLQEA
LQLHRPDFISRSGERIKRLKLIVQERKLQNILQNEREELFNSERLWPGSRNPVHRLPKRV
FLAVQKNRPIGRKEMIQRSKRI-YEQLPEVRKRREEEKRRSEYKSYRLRAQLYKTKVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPRPGELEEEEEE------EEEEA----------------------AAAAAANVD
DVVVVEEVEEEAGREL---DSDS-HYGPQHLESIDDEE---DEEAKAWLQAHPGRILPP-
------------PSPPQH----RYSEGERTSLEK-------IVPLTCHVW-QQIVYQGNS
RTQISDTNVVCLETTAHWGSGDDQKTESWHCLPQEMD-SSQTLDTSQTRFNVRTEDTEVT
DFPSLEEGI-LTQSENQVKEPN--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFAPD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHPL-
IGSTAVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDRYD-DLCSYMSWKTRKDTQWP
ENNLADKDQVSVATSSDITDENIATKRSDHFDAACSFGQYWTQEDSSKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDVITLDGLNE-----NAVV-CSER---VAEL-------------------------
------------------------------------------------------------
--------------------------QRKPTRELEYHSSDLRMLRMSPDTVPKARKHLKA
GDTSKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLAVSSPL----ET
TTGQHT-DTLNQKTLADTHLTEETLKVTAVPEPADQKTATPTVLSSSHSHRGKPSIFYQQ
GLPDSHLTEEALKVSAAPGLADQTTGVSTLTSTSYSHREKPGTFYQQELPESNLTEEPLE
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTG
TATVLSTPHSHREKPGIFYQQE--FADSHQTEETLTKVSATPGPADQKTEI------PTV
QSSS-YSQREKPS-ILYPQE-LADSHLPEEGLKVSA-VAGPADQKTGLPTVPSSAYSHRE
KLLVFYQ-QALLDSHLPEEA-LKVSAVS-----GPADGKTGTPTVTSTSSASSSLGEKPS
AFYQQTLPNSHLTEEALKVSVVPGP-GDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTLSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPSDSFSHREKPSIFYQQELPDNYATEKALKVS-TGPGPADQKTEIPAV
QSSSYPQRE-KPSVLYPQVLSDSHLPEESLKVSAF-PGPADQMTDTPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGLADQKTGTPTVTSTSYSQHREKPSI-F
HQQALPGTHIPEEAQKVSAVTG-PGNQ-KTWIPRVLSTFYSQREKPGVFYQQTLPGSHIP
EEAQKVSPVLGPADQKTGTPTPTSAS-------YS-HT-EK-PG-VF-YQ-QVL-PD-SH
-PTE-EAL-KISVAS---------------------------------------------
-----------------EPVDQ-TT-G---TPAVTSTSYSQYREKPSI-FYQ-QSLPS-S
HLTEEAK--NVS-AVPGL-AD-QK-TV-IPI-LPSTFY-SH-TE-KP-GV-FY-QQV--L
PHS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VASEPDDQTTG-TPT----VTSTSYSQHREKPSILYQQLLPGSHLTEEAK
NV------SAVPGPADRKT-GIPTLPSTFYSHTEKPGS---FY-QQ-V-LP-HG-H----
LPEEALEVSVAPGP-VD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPDGNLPEESLKVS
VAPG-PVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSYSFGEKPIVNYKQAFPDGHLPEEVLKVSIVSG--------PT----E
KKTDIPAGPL--GSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETL-PVHS
TTYSNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSYREKPIV
FYQ-QALPDSQLTQEALKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NISYQQELPDS
HLTEKALKVSDVPGPADQKTGVSTVTSTSYSHREKPIISYQRELP--HFTEAGLKILRVP
---DQKTGI---NILSSNSYPQREHSVISYEQELPD--LTEVTLKAA---GVPGPAD-RK
TGIQIASSSSYSNREKASTFHQQELPD--ITEEALNVFVVPGEGDRKT-EIPTVPLSYYS
RREKPSVISQ--------------------------------------QELP--DSHLTE
EALKVSPVSIPAEQK-TGIPIGLSSSYSHSHKEKLKISTVHILDDQKTEFPAATLSSYSQ
IEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPVSLSSSYFHREKSNI--FSPQELPGRHVTEDVLKVSTIPGPAGQKTV
LPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DVGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENMALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTGVS--NGDLL-QRRPF---TEESPS-SRCIQK
DIGTQ--TNLKCRRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIVPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EHPQLDSHPCA-FR
SAEPSEMTRG-RQNPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLQMPFH---EKMDPWLSELV-----EPAFVPP---KEVDFRSSSQMPSPEPMK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
TSSPSSFKTHSNSQDK--EVTILAEGRRQSQKLPVDFEHSFQEEKHLERSDFTGSHSEPS
TSANFSNFKEIQISDNH-TLISMGRPSSTLGVSRSSSRLGVKEKNVTITPDLPSCIFLEQ
RELF--EQSKAPRADDHVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQMRENHSPLPQGQDSIASDLPSPISLEQC----QS-KAPGVDDQMNKHHFPLPQGQD
CVVEKNN-QHKPKSHIS-NINVEAKFNTVVSQSAPNHCALAAS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDERFHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVAQDQESLGFLGPKSSLDFQVIQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSADRLPEKMK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEIIEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSIKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAIAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLQNENADASVQVLITGDENLSDKKQQ-EIHSTRAVTEAAQ
AKEKESLQKHTADSSAAAAAEHSAQVGDPEMKNLPDTKAI---TQKEEI-HRKKTVP--E
EAWPNNKESLQINIEESECHSEFENTTRSVFRSAKFYIHHPVHLPSDQDICHESLGKS--
---VFMRHSWKDFFQHHPDKHREHMCLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVMDTTKSQ-ARDYPKHNGQISDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERSV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTRELKKSKVLS----------HHRAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRHIQVANHVISSDSISSSASSFLSSNSTFCNKQNVHML
NKGTQ-AGNLEIVNGA-KKHTRDVGITFPTPSSSEMEKSSTAVT---------------Q
S-S---------------LQQNQTQGHPVASDRVSWFVPVENVESRSKKENVP-NTCGPG
ISWFEPITKTRPWRKPLREQNWQGQHLDSRG----SLAGPGREAGRDLLKPFVRATLQES
LQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDALFNIDRERQGHQNCMRPLPKRV
FLAIQKNKPISKKEMIQRSKRL-GVVSKKIKSYL--KRVLHTWKIYM-------------
--------------------------------------------------

MEPEDQPWQGELEEEEE---------EEA----------------------AEAAAANLD
DVVVVEEVEEEAGREL---DSES-HYGHQHLESTDDEEDEEDEEAKAWLQAHPGRILPP-
------------PSPPQH----RYSEGERTSLEK-------IVPLTCHVW-QQILYQGNS
RTQISDTNVVCLETAAQQGSGDDQKTESWHCLPQEMD-SSQTLDTSQTRFNVRTEDTEVT
DFPSLEEGI-LTQSENQVKEPS--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFAPD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSCFSVSQHLL-
IGSTAVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDSYD-DLCSYMSWKTRKDTQQP
ENNLADKDQVLVATSSDITDENIATKRSDHFDAACSYGQYWKQEDSPKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDIITLDGLNE-----NAVV-CSER---VAEL-------------------------
------------------------------------------------------------
--------------------------QRKPTRELEYHSSDLRMLRMSPDTVPKAPKHLKA
GDTSKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEVLSQLAVSSPL----ET
TTGQHT-DTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSQSHRGKPSIFYQQ
GLPDSHLTEEALKVSAAPGPADQTTGISTLTSTSYSHREKPGTFYQQELPESNLTEEPLK
VSAAPGPVEQKSGIPTVSSTSLSHGEDLLFFYRQTLPDGHLTDQALKVSDVSGPADQKTG
TATVLSTPHSQREKPGIFYQQE--FPDSHQTEETL-KVSATPGPAHQKTEI------PAV
QSSS-YSQREKPS-ILYPQE-LADSHLPEEGLKVSA-VAGPADQKTGLPTVPSSAYSHRE
KLLIFYQ-QALLDSRLPEEA-LKISAVS-----GPADGKTGTPTVTSTSSASSSLGEKPS
AFYQQTLPHSHLTEEALKVSVVPGP-GDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLL
PEEALKISAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPSGSFSHREKPSIFYQQELPDSHPTENALKVS-TGPGPADEKTEIPAV
RSSSYTQRE-KPSVLYPQVLSDSHLPEESLKVSAF-PGPADQMTDTPAVPYTFYSQR-EK
PGISY------QQTLPESHLPKEA-LKISVAPGPADQKTGTPTVTSTSYSQHREKPSI-F
HQQALLGTHIPQEAQKVSAVTG-PGDQ-KTWIPRVLSTFYPQREKPGIFYQQTLPGSHIP
EEAQKVSAALGPADQKTGTPTPTSAS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISIAS---------------------------------------------
-----------------EPVDQ-TT-G---TPTVTSTSYSQYREKPSI-FYQ-QSLPS-S
HLTEEAK--DVS-AVPGP-AD-QK-TV-IPT-LTSTFY-SH-TE-KP-GV-FY-RQV--L
PHS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VASEPVDQTTG-TPT----VTSTSYSQHREKPSVFYQQSLPGSHLTEEAK
NV------SAVPGLADGKI-GIPTLPSTFYSHTEKPGV---FY-QQ-V-LP-HS-H----
LPEEVLEVSVAPGP-VD-QTIGTPTVT-SPSSPFGEKP-IVIYKQAFPV-----------
------------------------------------------------------------
------------------------------GHLPEEALKVSIVSE--------PT----E
KKTDIPTGPL--GSNALGEKPITFYQQALLDSPLNKEVVKVSAAPGPADQKTETI-PVHS
TTYSNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETLSVSSSLYSYREKPIV
FYQ-QALPDSQLTKEALKVSAVPRP-ADQTTGLSTVTSSFYSHTEKP--NISYQQELPDS
HLTEKALKVSNVPGPADQKTGVSTVTSTSYSHREKPIISYQQELP--HFTEADLKILRVP
GPADQKTGI---NILSSNSYPQREQSVISYQQELPD--LTEVTLKAV---GVPGPAD-QK
TGIQIASSSSYSNREKPSIFHQQELPD--VTEEALNVFVVPGQGDQKT-EIPTVPLSYYS
HREKPSVISQ--------------------------------------QELP--DSHLTE
EALKVSPVSITAEQK-TGIPIELSSSYSHSHKEKLKIST-------KTEFPAATLSSYSQ
IEKPKISTVIGPNDQKTPSQTAFHSSYSPTVKPDILFQQQLPDRDQSKGILKIS-AIPEL
ADVN-----TGKPIPLSSSYFHREKSNI--FIPQELPGRHVTEDVLKVSTIPGPAGQKTV
LPTALPSSFSHREKLDIFYQKDLPDRHLTEDALKISGALGQADQITGLQTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DVGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENTALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NGDLL-QRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCRRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEERQVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCSRTLTS-EHPQLDSHPCA-FR
SAEPSEMTRG-WQSPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFH---EKMVPWLSELV-----EPAFVPP---KEVDFHSSSQMSSPEPMK--K
FSTSITVSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
TSSPSSFKMHSNSPDK--EVTILAEGRRQSKKLPVDFEHSFQEEKPLERSDFTGSHSEPS
TNANCSNFKETQISDNH-TLISTGRPSSILGVGRSSSRLGVKEKNVAVTPDLPSCIFLEQ
RELF--EQSKAPHADDCVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKALHV--
-DHQMRENHSPLPQGQDSIASDLSSPISLEQC----QT-KVPGVEDQMNKHHFPLPQGQD
CVVEKNN-QHKPKSHIS-NINVEAKFNTVVSQSAPNHCTLATS--ASTPPSNKKALSCVR
ITLCPKTSSKLDSGTLNNRLHSLDAASKARMKSEFNFDLHT----VSSRSLEPTSKLLTS
KPVAQDQESLGFLGPKSSLDFQVVQPSLLDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSADRLPEKMK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEIIEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSRKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAIAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKKVVTKASLP---VGEEPLRNENADASVQVLITGDENLSDKKQK-EIHSTRA------
AKEKESLQKDTADSSAAAAAEHSAQVGDPEIKNSPDTKAI---TQKEEI-HRKRTVP--E
EAWPSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGKT--
---VFMRHSWKDFFQHHPDKHRKNICLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVMDTTKSQ-ARDYPKYNGQINDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LSDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERSV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKSKVLS----------HHRAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSSTTSIVESD
TLTQTDREMAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQKRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRHIQVANHVISSDPVSSSASSFLSSNSTFCNKQNVHML
NKGTQ-AGNLEIVNGA-KKNTRDVGITFPTPSSSEAKLEEDSDV---------------T
S-WSEEKREEKIIFAGYPGDRKLKKN-KNSHEGISWFVPVENVESGSKKENVP-KAHGPG
ISWFEPITKSKPWREPLREQNSQGQHLDSRG----SLAGPGRGDGRDPLKPFVRATLQES
LQFHRPDFISRSGERIKRLKLIVQERKLQSMLQSERDALFNPDRERQGHQNRMCPLPKRV
FLAIQKNKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNH
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEE--EEAAVAAA-----------------------TGEEEAANLD
EVVVVEVVEEEAGRDL---NSDS-HCEHRHVESTDDE---EDEEAKAWLQAHPGNILPP-
------------TSPSRH----CYSEGKRTSLEK-------IVPLTCHVW-QQLLYQGNG
RTQISDTNV---ETAAQQGSGDDQKTESWYYLSQEVD-SSQTLDTSETRFNVRTEDTEVT
DFPSLEEGI-LTQSENQVKELS--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFTPD
SLFQQSELSFAPLREIPDKSEDTEWFSRPSEVSEALFQATAEVASDLASSCFSISQHPL-
IGSTVVGSQCPFLPSEQGNNEETIL--SIDELKIPKDGDSYD-ALCLYMSWETQKDTQQP
ETNLADKDQVSIATSSDITDENIATERSDHFDAACSYGQYWKQKALPKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDVVTLDGDAECCSLNENIV-CSER---VAEL-------------------------
------------------------------------------------------------
--------------------------QRKPRRESEYHSSDLRMLRMSPDTVPKTPKHL-A
GDTSKGS----------------------IAKVTQS------------NLKPGI------
---ITTPVDS------------D----I------GSHLSSSLEDLSQLAVSSPL----ET
TTGQHT-DTLNQKTLVDTHLTEETLKVVAVPEPADQKTATLTVLPSSYSHRGKPSIFYQQ
GLPGSHLTEEALKVSAAPGPGDQVTGIPAVTST---HGEKPGVFDQRELPESNLTEKPLK
VSATPSPVEQKTGIPTVSSTSHSYGENPLFFYRQTLTDGHLTDQALKVSAVSGPADQKTG
TATVLSTPYSRREKPGVFYQPQ--LPDSHQTEETL-KDSFTPGPADQKTEI------PAV
QSIS-YSQKENPS-ILYPQV-LADSHLPEEGLEVSG-VSGPADQRTGLPTVPSNAYSHRE
KLLIFYQ-QALLDSHLPKEA-LKISAVY-----GPADEKTRTSTVTSTSSVSSSLSEKPG
AFYQQTLPSSHLTEEALKVSVVPGP-DDQKTGLPSTPSSFYSQRQTPIIFSQQTLPDILF
PEEALKGSAV---STQKTGTPTVSSNSPSYRDKSSIFYQQELPNSDVRRESLKMSAIPGL
-TDQKT-GTPTVPSGFFSLGEKPSIFSQQELPDSHPTEKALKVS-TGPGPADQKTEIPAV
QSSSYSQRE-KPSVLYPQVLSDNHLPEEGLKVSAL-PGPADQTTDTPAVPS-FYSQR-EK
PGILY------QQTLPDSHLPKEA-LNVLVAPRPADLKTSTPTPTSTYYSQHREKPSV-F
HQQALPGTHIPEEARNVSAITG-PGDQ-KTWIPRVLSAFYSQTEKPGIFYQQTLPGSRIP
EEAQKVSAVPRPADQ-TGTPTPTSTS-------YS-HT-EK-PD-IF-YQ-QTL-P----
------------------------------------------------------------
-------------------------------------------EKPDI-FYQ-QTLPG-S
HIPGEAQ--KVS-AIPRP-AD-Q--TG-TPT-PTSTSY-SH-TE-KP-GI-FY-QQV--L
PDS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VAPEPVDQTTG-TPT----VNSPSYLQHRENPRSFYQQLLPSSLLTEEAK
NI------SVVPGQADQKT-GIPTLPSTFYSHTEKPGI---FY-QQ-V-LP-HS-H----
LPEEALKVSVAPGP-VD-QTTGIPTVT-SPSNSFGEKP-IVIYKQAFPDGHLPEESLKVS
VVPG-PVDPTPGTPTVTSRFYSQHRVKPSSFYQPPLLGSQIPEEALRVSS-ASGPADHTT
GIPTI----TSPSYSFGEKPIIIYKQAFPVGPIPEEALKALVVSG--------LT----E
QKTKIATGPL--GSSALGEKPITFYQQALQDSPLNQEVVKVSATPEPADQKTETP-PVYS
ITYSHRGKPVIFYEQT-LSDSHLSEEALKVPPIPR-PDAQKTGTPSVSSSLYSHSEKPIV
FYQ-QALRDTQLTKEALKVSVVPHP-ADQ-TGLSTVTSSYYSHTEKP--NISYQEELPDS
HLTEKALKVSDVPGSADQKTGVSTVTSTSYSHRDKPIISYQQELP--HFTEATLGILR--
EPADQKTGI---NILSSNSYPQREQSVISYQQELPD--LTEVTLKAI---EVPGPAD-QK
TGIQILSSSSYLNREKPSVFHQQELPD--VTEEALNVFVFPGQGDQKT-DIPTASSSYYS
YGEKPSVSSQ--------------------------------------YELP--DSHLTE
EALKVSPVSIPAEQK-TGIPIGLSSSYSHSHTEKLKISTADVPDDQKTEFPAAALSSYPQ
IEKSKISTVTGPDDQKTPSLTVFHSSYSQRVKPDVLFQQQLPDKDQSKG-LKIS-AVSEP
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRYVTEDVLKVSAIPGPAGQKTV
LPTAPFSSFSHQEKPDIFYHKDLPDRHLTEDALKISSALGQADQITRLQTVPSGTYSHG-
---EKHKLI-SEH-VQRLIDNLNSS-G---SSFSSNN--VLLN-SQADD--RVLIKKTES
AGLR----DVGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDLS--NVELL-QRQAF---TEENPS-SRCMQK
DIGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAENK-ASMALE-ETLRRYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TIIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSIDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGFQSPRGMGCKPEAVCSHIIIQSHEKGCFRTL-S-EQPQLDSHPCV-FR
SAEPSEMTRG-RQSPSSCRARHVNLSA-PLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFR---EKMDPWLSELV-----EPAFVPP---KEVDFHSSSQMPSPEPMK--N
VTTSITFSSHRHSKGISDS--SVVKVGVTEG-SQCTGASVGIFNSHFTEDQNPSRDLKQK
TSSPSSFKMHSNSPDK--EVTIVAEGRRQNQKLSVDFEHSLQEEKPLERSDFTGSHCEPS
TTADSSNVKEIQISDNH-TLISRGRPSSTLGVSRSSSRLGVKEKNVTITPDLPSCIFLEQ
RELF--EQSKAPHADHHVRKHQSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKVPHV--
-DHQMREKHSPLPQGQDSVASDLPSPISLEQC----QS-KVPGVDDQMRKHHFPLPQGQD
CVVEKND-QHKPKSHIS-TINVEAKFNDV-SQSAPNHYTLTTS--ASTPPSNRKALSCVR
ITLCPKTSSKLNSGTLDKRFYSLDAASKARINSEFNFDLPT----VSSRSLEPTSKLLTS
KPVAQDQESLGFLGPKSSLDFQVIQPSLPDSN-TITQDLKTMPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSTDRLPEKKK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INPEDRGHEITEPSNQ-KLRKASVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSS--DSKSDTTIESSHSGSNDAVAPDFPA
QVLGTRDDDVS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGGKPLRSDSADASVQVQITGDVNHSDKKPK-ESPSTSAVTEAAQ
AKEKEPLQKDTADSSDAAAAEHSAQVGDPKIKNSPDSKAI---TQKEEI-HRKMTIP--K
EAWPKDKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDVCHESLGRS--
---VFMRHSWKDFFQHHPDKHREHICLPLPYQNMDK-------TKTDYTKI-KSLSINVN
LGNK----EVMHTTKSQ-ATDYPKYNVQINDP--KRDQKLTPEQAAQHTVSLNELWNKYR
ERQRQQMQPR-----LDDRKELSLVERLDRLAKLLQNPITHSLQV-SESTPDDGRGERGV
KE-WSGRQQQ-RNKLQKKKPFKSLEK-SHRNTGELKKSKVFS----------HHGAGRSN
QIKIEQIKFDKYILSKQPGFNY-VSNTSSDCRP-SEE-SELLTDTTTNVLSSTTSAVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTCHPQMTSEHTRRRRIQVANHVISSDSISSSVSSFLSSNSTLCNKQNVHML
NKGIQ-AGNLEIVNGA-KKHTRDVGMTFPTPSSSEAKLEEDSDV---------------T
S-WSEEKHEEKMLFTAYPVDRKLKRNKKNSHEGVSWFVPVENMESGSKKENMP-KMCGPG
VSWFEPLTKAKPWREPLREQNWQGQHLVGRG----SLAGPGREDGRDALKPFVRATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLQSMLQSERDALFNIDRERQSHQNCIRPLPKRV
FLAAQKNKPISKKEMIQRSKRI-YEQLPEVQKKKEEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-----------------VGAPGI-LSTYSNGIKPGSFSQEEWPDRHLTEETQKASASPGL
-ADQKP-GTPTIHSSSYSQGMKPGIFCQQLLSHRHPSKESLDVS-AVSRSSDQKTW----
-------------VFYQQTLSDSHLTEEALPVPVV-PSRSSQKTSLPSESSGSS------
-------------SHRDTHLPEDA-VKVSADSGSADQNANSPTM-SSSSYSHKKKPS--I
YQQELPGSHVPTGTWKIAFVPE-STAQ-KPGM----------------------------
-------------------------S-------HL-YS-EK-PI-VF-FQ-QEL-PD-SY
-PVE-KPTKAL-------------------------------------------------
------------------------------------------------------------
-------------FVPGP-AD-QL-SG-VPT-LTTASY-SC-EE-KP-SI-SY-QQK-F-
PDS------------------------------------------------HLTEN-M-L
K-VSGA--PGPA-DQ-K-TG-TSK-VS-STSYS---------------------------
------------------------------------------------------------
-------------------------------RRERP-G-I-FY-EQ-A-LP-DG-P----
VSEEALKASTASRP-AD-QSITIPSIT--STFSQREKP-GGFYQQAMPGVHLPGVSLKAS
AAPE-PADQNTGTLAISSGPH-PLGEESIIFYQSRLLGSPLSAENFTVPL-VSGATEQKT
DTPTGVSIGYPGSHPVGEKHIIFYQQALPDSHLPKETLNVLTSPG--------PV----D
LKTGEPTIYS--TSYPFGEKPIILYQQALPEAQLTKE-----VVSGPVDQKTGIP-LITS
SSCPNLENVIDSYQQE-LPDGHLTENTKKVSVVPG-PTDQKTGIPT--------------
-----------------------------------VPP-TSSCIVRP--SASYQQELPD-
-LSEKALKALGVVRPAQQKTGIQILSSTPYSHKGRPSISFQQELPD--LTKEALQVLGVP
GVSKQKTE---------------------------------EALGVF---VHPGPVV-QK
VGIPVEPLSYYSQR-EPSAFSPQELPASHLTEEALNVPALSVLGTQKP-GAPSGPSSSYF
HREKLNDF--------------------------------------YQRALP--YHHPTE
GSLKASTVPGLYDQN--RRPTVPSGSCSF--KEKVKISTADLLHDQKTKLPTAAHSSYLN
REKPVISTVIRPDDQKTPLLTVFHGSYPQRIKPVIFFQKQLPGRDQSEDTLKIS-TDSEP
TDVN-----TETPVLLSGSYSHTEKADT--FYPQELPDRHLTED----------------
-------------------------------APKGSSGLGQVDQIAWVPTVSLGIYSHD-
---EKHQLV-SEH-AQRPIDNLNSP-D---SFLRPNN--MPLNSQIDDA---VIISKPES
STIG----DVGY---EEIRDADN--SSKT-LKEIRTLL-ME-AENIALKGCNFPA--PLV
LFRDVSD-V--SFIQSKKVVCFKEPSTTDVC-------NQRDPV---TEECPR----MQK
DIGTQ--TNLKYQRGI-ENWEFISSTTI--RSPLQEAEDT-ARVAFD-ETFRQYEAA-RS
AMR-SEPEGY-SAAIGN-KIVIPMM-TIIKSDSN-SDI---SDGCCSRDSNLP----ESL
ESASD-IFLNS-FPYTSPKTS-MTD--SRDEEGLSENEDSCG-SIDSLAAHVKYLLQCES
SLNQAKQILRNAEEEECRVQA--QAWNLKFNLGHD--YGYSISELNEDDRKKVEEIKAKL
FGHERAAHVSEDLQSPWGIGCVPKAVCGHIIIESHEKGCFRTLTA-EQPHLHGHPCV-LR
SADPSEVIRG-RRSPSSWRTRHINISK-SLDQSNPRFKVWDSLQLQSHPPFQQLTPEDFK
ISKGVGVSFN---ANFDPRLSELV-----EPTCMPS---EEMDFPSSTQTSPPEPMK--Q
FTTSITLSSHQHPDCISDT--SVFKVGVTEG-SQCTGPSGWVCKSHKPEEQISPKDLTQK
TPSPSSLKRHSHSP-----VTILAEGDRQRHKLPVDSEHSHQKGKLLERSYFKASHSDPS
VSTNYSNFKGVQFSHKD-ILIILDKLSSTS---------EVKEKNVALTPDLSSCIFLEQ
QELF--EQSHTPHTDHHVRKYRSPS-------CPDIASCIFL--EQQELFEQSKAPHT--
-DHTMREDHALLPQCHDYIVSDLPS-VFLEQQQY-----KSQDVDDHMRN----LSQGQC
SVVEK-I-ECIPKSHFSNLINVEAKFSNMISQSAPDHCT---S--ASTPPSNRKAISCVH
ITLCPKTPSKLDSGT-DERFHSLDPASKTRINSEFNCDLQT----ISSRSLEPTSKLLTC
KPVAQDQEFLGFQGPKSPLDLEVVQSSLPAS-KTVTQDLKTIPPQNSQMVISRQTQVNIS
DLEGP---Q--GTPVSADGSRDQSE-TP----SGKLF-SDAVTQITTESPEKTTFSSEIF
INAG------LDPTTQ-KPHKFPVKFASSSSVQQHTASRGK-------------------
---DAQRELLPYKPSGSSKMYYVPQLKTVPSFP--DFKSDTTVESSHPGSNDAIAPDFPP
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRAVTK--------GKKRFQKDNAEAPVQAPITGDV-------QKEIISGVFLTKTAR
PEEKESLQDTTDS--------CDAAVQDRKTERLADTKFI---KQTEET-----------
---------------CSECHSSFENTTHSAFRSAKFCFDHPVHLPHEQDICHESLGRS--
---VSMQHSRKDFFHHHSDTHREHSCLPPPHPSVDK---------MDYSRI-KSLSINLN
LGDI----EKMHTTKSQ-SKDHPKSKTQMNDP--KKELKVTPELTAQCTVSLNELWNKYQ
ERQKQQKPPD-----ICDKKELSLVERLHRLAKLLQNPITHSLQF-SESTQDDSRRGHGA
RGQGGGRQQQQKSRTQKQKWCKSLEK-GPQNAGYRGPSRELS----------PQQDNSSS
QIKTEQIKLNKYILRKQPDFNF-ISNSSLDSRP-SEE-SELLTDSPTNCLSSTTSPLDSD
VLTQTDREVTL-HERSSSISTIDTARLVQAFGRERLYLSPRRIKLYSSITNQQRRYLEKR
CKHNKKTLNTGHPQMTSEHTRRRHIQVADHLVSSDSV-SSTSSFLSLNSTPCNEQSVHLL
NKSIQ-TGNFEIMTGT-KKHTRDVGVTFPTPSSSEARLE-DSDM---------------T
S-CPEEKVQEKMFFISYLGNKKLQKDKPKSCKGVSWFVPVEYVKSASKKENLP-NVYVPG
ITWFEPVTRTKPWREPLREQNWQGQCTDGWW----SLGGPGGDGGCVPPRPFVRATLQEA
LQLHRPDFISRSGERIKRLKLTVQERKLQNMFQSERDVLFN-----------VHPLRRRV
FLAPQN-KPIGKKEMIQRSKRI-YEQLPEVKKKREEEKRKSEYKSYRLRAQHYKMKVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEGEKEEEEEEKAVEPA-----------EVAEQEDSV----KSD
ETVLVEEVEEEARPEL---NVDF-DFEFQSRESIDD--EEEDEEAKAWLQAPPEASFSL-
------------PPPPRH----SYLTGERTSREK-------IVPLTCNIW-QQPLYQGNV
RTQSSDTSFVSLETTSQWSSEDDQRMESWHGLLQEKKSSPQSLDTSQTRINLKAERSKVT
ESSFLEEGV-LTQSEGQVKKL-------SSPLLVIQDDFATPDLPLLTCLTQDQ-EFGPD
SLFHQSELDFAPLRGIPDKSEDIEWFSRPSEVSEALLQATSEASSDLVNSCFSVSQYPL-
LSSTNIGSQHSCLSPEQKSEEYV-----VNDLKTPKEVDSYN-VLCSCMSWNLGKDTKQS
ENNLADKDQVSVSTLSAISDDNIATKSNDSFDASSEHVQCWKEEALQ-QAETCLNSTDNI
CFP---------------------------------------------------------
---QEVATPPHSKRSYSFLRCLLERRGKKEAPLDPE---------NHYFENVDLRVPAEN
EVKQKMDFLEGYEG-NEDLQKELSRYFEQNESRSNLASSEVHPTSPEMNYAENVVVVDN-
-SVRFSEAHI-LSRGHDISKTETV-----------EVQLDETSEPLYFEEERNQ------
----KATSIFGENNIDA----------TENVAFEAVIASIESTKIESTVN----------
--DSQERQPPNPDLSQLNYPDEN---SFFD-KFKHPNY-------QSALGVFEPADSESL
LP-----KEYDDSSLHWYPNIKSP-PNAPQNMFIKPLFVISELKPS-------DSLSEKS
YNQAIGQGKTQSALFQCDK-YNESFLPFGKIKSISGLDLAKKVGSSNIIC-PM-------
--KQDLKQQTFEEVADSSD-----------------------------------------
---------------------------------------------------HNLEDLHGK
A-KSDVITLDGDSKCRSLDEHAVVCCEK----VELQ------------------------
------------------------------------------------------------
----GKVSHSNLCINQSFSSTLPSFAPYEPTRDSEHHSSNLRMLRVSPDTPLTSD-----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------DQKSGIATVSSVPYSPRDQPGIFYQP
VEPKGHLPEETLKTSAPLGPADQKTGISLSTKNSYSQRKH--------------------
------------------------------------------QES-----LPVSHPTDCG
IPIVTSVPYSYREEPDKFFQQV--LPESHLSEESL-KTSGIIGSDDKKTRI------PTV
SSAL-YSNGE--------------NHLTEEL-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------RKVS-VSPRPGDQKIGMPSE
LSSSYSQREKPS-IFFQQTLPGSYLFQEALKV----------------------------
----------------------------ASDSGSADQNSGIRAV--------PSRPSV-I
YQQELPDSHQVEKSLKVVVVPG-PDGQ-KSGISI--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------VSSTPY-SQ-RE-KP-II-FY-QHT-L-
PDR-----------------------------------------------IVEANK-I-L
S-V-----SGSA-NQ-I-PG-VSI-TP-STSYL---------------------------
------------------------------------------------------------
-------------------------------YKEKS-G-I-CY-EK-R-WS-QS-H----
LTEATLNISGVSGT-RD-QKTETP------------------------------------
---------------IPSASY-LQREKPGIFYQQAIPGSPIPRESLKVSV-VPGPADQNT
GTPI-----------LGEESIIFYQHALPCSPLTNGALKVSAISR--------QA----K
QKIGTPVEPS--DSYLLGEKSI-FYQEGLQESHLHKDPLKVLVFPEEVDQKPGIP-PVTS
LSYSSQQKTIVSYQQE-LPDSNQTEKNMNISVVPG-PTDQKSRIST--------------
-----------------------------------VP---------S--GISLQQYLPD-
-HSEEVLKVLGVFRPAEQNTGIQIVTSTPYSHKEKPIISYQQELPD--ITTEALKVIGVP
RLADDMSGI---YIVPSPGYSQKEEPVISYQPE--VPSLIEGTLKTG----VSGPKD---
---------PYSHTEKPSVPTVPVSSH--LTEESPKVSAVSVSAEQ---KKPTGPSS---
------------------------------------SSQRENPSDFYQQTLP--DGDLTE
GSLKSSTAPGPTEQN-R-SPT-VPSSYSH--KEKLKISTANLLDDQKTELPTATHSSYLQ
REKPKVSTVIGSDDQKTPL-AVFRSFYSQKVKPGIFFQQQLPHKEQSKN---IS-TVPEP
TD-------------------------------------------------------KTV
LPTASSSSFSHKEKGNSFYQKDLPDRHQTENSLKGSSGLGKAEQITGLPTVSSGTYSHD-
---KKQELV-SEH-VQRLADNLNSD-S----NVCSNN--MLLNSETDDG---VIISKPES
QSFG----DVVF---EEIGDSDN--GSKT-LKEIRTLL-ME-AENIALKRCNFSA--PLV
PFRDVND-I--PFVQSKKMVCFKEPSKTD-----------RQTF---TEESPS-IRCIQK
DIGTQ--TNLKFQRGI-GNWEFISSTTL--RSPLQEAESK-PRVSLE-GPFRQYEAA-RS
MMR-SEPEGY-NGTIGN-KMIIPMM-TIIKNDSS-SDVSD-GNGSCSWDSNLP----ESL
ESVSD-VVLNF-LPCVSPKTS-ITD--SREEECVSDSEDGYD-SVDSLAAHVKNLLQCES
SLNHARQILKNAEEEESRVRA--QAWKLKLNLAHD--YGYPISELNEDDRRKVEEIKAKL
FCEGRTADFSE---SPRGIGCPPESVCSHIIIESHEKGCFRTVST-QPPQVNSHPCV-SR
SVEPSEVIRG-RRSPAPWRNRHINFSK-SLDQNNPHLKVWNSLQLQSHPPFQNLMHDDFK
ISKSFGVPFR---ENIDPWLSEI------EPAFVPP---KEVDFHSSPQILPSEPMKQKQ
FTTSITFSSHRHSKCISDS--SVFKVGVTQG-SQYTGAPVGVFNSHVIEEQISPRDLKQK
ASSPSSIKKLSYLPDR--EMTILAEGSRQSQTLPVDSEHSHQEEKLLERSGFKVSHSEPR
---NGTNSKEVQLSDNN-TLISMDRPSSTL---------GVKEKNVIITPDLPSHIFLEQ
RELF--EQSKSPHTDHSVRKHHSPP-------CLNLPPCIFL--EQKELYEQSKVPHV--
-DHEMRKSHTPLPQCQDSVASDLHSPICFEQH----QS-KAPGVDA----HHFLFSQGQD
CVVEK-T-QHRPNSPISNLINVEAKFNNVISQSAPDYCQLETS--ASTPPSNRKALSCIR
ITLSPKTPSKLDSGTLDKRFHLLDPASKTRMNSEFNRDLQY----KSSESLEATSKLLTS
KPLAQDQEYVGFLGPKTPPDLQAVQSPFPDS-KTIIQDLKNLPSQNSQIVTSRQTQVNIS
DLEGYSKPE--ETPVSADGSREQSK-PHFSASSGKLS-SDAVTQITTESPEKTMFSSEIF
INAGDC----EEPSTS-KPHTVPVKFASSSSVQQISPSHGV-------------------
---DAQPVLLPYKPAGSQKMYYVPQLEAIPSFPD-CKSSDTTLESSHSGSNDAIAPDFPA
QVLGTRDDNPP--------------------------------------DTVNIKHEEGI
YSKRAVTKPF-----------QKGDAEAPIQVPE-----ILSGKHKEEIFSQRVVTKIAW
PEGSECLQKDTEA-----------QIQDKKIENLPETKFI---QS---------------
-----------FFLTESKCHSEFENTTHSVFRSAKFYFHHPVHLPNDQDFCHESLGKS--
---TLMRHSWKDFFQHHSNKLR----------DVDK-------TKMDYSRG-KSLSINMN
LGDN----EEAHASKSQ-ARDNLKNKRQINDP--KKDHKVTTELTTQPTTSLNELWNKYQ
ERQKQQKPLD-----VSDKKELSLIERLDRLAKLLQNPITHSLQV-SESTLDDSRGERDF
KE-WNNKQQ--KKKLQKQKRYRSLEK-GHKNIGDLKKSKVAS-----------HQTGKSN
QIKIEQIKFDKYILKKQPYLNY-ISNTSSDSRP-SEE-SELLTDTTTNILSTTTSPRDSD
ILTQTDREVTL-HERSSSISTIDTARLIQAFGHERVCLSPRQIKLYSSITNQQRRYLEKR
CKHTKKALNISHPQMTSEHTRRKHIQMANHRISSDSV-ASASSCLSLESTLCTEQIVPMF
NKGIQ-AGNLEILDGV-KKHTRDVGVTFPTPCSSEARLEEESDE---------------T
S-VSEEIIKEKTLFASPLEDKKLK-SKQNSYEGVSWFVPVENVKPATKKENCP-KSYGPG
ISWFEPMSRTKPWREPLREQNWQKQCMVGWG----LQPGPGGDVGQEQLTPFVRTTLQES
LQLHRPDFISRSGERVKRLKLIVQERKLQNVFQSERNALFNA----------MHPLPKRV
LRIVQKNKPIGRKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSNRLRAQLFRKKLTSQ
LLGR--KVPWD---------------------------------------

MELEDLPWPGELEEEEEEEEEEEEGEEKKKEERTA---------EAAAAEEEP----AAW
VEIVTEEAVEEAGREV---DSDS-NYEVQPRPNS----EEEDEEAKAWLQARPGVLS-P-
-----------PPPPPRY----SCARSERTGAEKVSGAGEPSEPVWCRVW-EAHLMIV--
------------AGSVRGRTREERETESWQCLPQEID-SSQTSDASQMRINVKLKGNKEI
NVPSLEEGV-SIQSEDQVKEPN--RNLLCSPLLVVQDSLASPDLPLLTCLTQDQ-EFGPE
FLFHQSELDFAPLRGIPDKSEDPEWFSRPSEVSEALFQATLEVPSDFTSSCFSISQHSI-
TGNTTAGALHCFLSFEQETNEDDVLSGSVDELKTPKGCDNYD-VLYSHMSWKTQKEIQQP
ESILADKGQVSVSSLPDSSDENGVTKRSDSFVGSCSDLQCWEPEALQ-QDLVFFPHDAAP
HNK---------------------------------------------------------
-------------------QCLLEKRGKGV-PLTSAS---------HDCKSDYLRAQAEN
E--------------NEGLQRELCQHFKQKETRNNLVSSEVYPRPSEMKCSRNFIVPDN-
-SVKVSEAHML-SRGHGISKMESSGGPLQT----ARSNLNETSKQLCFQEERN-------
----QKATIFGEKNVNA----------TENVAFEAVTASLEPSKKDSIISEILTEISKSS
KDESHEQELKNPDLSPLNYCNDES--SLFD-KLRHPYY-------QYTPGVFELAVSEPL
L----HKEDDDANFLYWYTNFK--------------------------------------
---------------------------------------------------------SPP
IHLK----------------------------------------------KC----SLRH
FLLFR-SLIITVGQETLLKADRSQGEILWPVGAECRFTIYTVMQ----NDSCFVEGLQGK
A-DSDVITVDDDTECCSLDEKAVVCSER---VAELR------------------------
-----------R------------------------------------------------
-----EVGHSDLGINQSVSSVSPGFIPYEPTRALEHRPSNLRMLRFSPDTVLKSITT---
------------------------------------------------------------
------SG--------------------DS--DIGSHLSLSSEGLPQLAVNSQK-----N
TTGQLV-DTLNQKAWPD-------------------------------------------
---------------------------------------------------SHQT-----
------------------------------------------AASLKVSHITEPPDQKTG
LPTEPSTSYPHDEKPNVLYQES--LPGGHLTDQSL-TVSAVLRPADQKTET------TTV
-PSS-YSNKEKPS-IFYQQE-LPGSYQTEEGVKVSA-IPGALDQKTGISTIRTTPSSHRE
ESGIFYQ-EELPESHLTEET-LKLSGVL-----GPPD-----------------------
------------------------------------------------------------
------------------------------------------------------------
---QKS-RTPHI-------TSKPSSLYQEGLPDGHPSEQSLKVS-AIPGSANQKTGIQNI
TSPSY-------------------------------------------------------
--------------------------------------------------SQKDKPDL-F
YQQALPDNQLTEETLKVSVAPK-PAEQ-KSRITTVS------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------PTSY-SP-GK-KS-YA-LN-LQA-L-
PES------------------------------------------------HLTDK-N-L
K-VLAIPG---I-DQ-K-AR-TVT-VP-STSNL---------------------------
------------------------------------------------------------
--------------------------------LREN-S-S-FY-QQ-E-LP-QS-H----
LTEETLKTSTARGP-DD-LKTKILTTH-SDFYSQREKP-GISYQQTLSDIYTTKEPLKAS
AFYG-LADQKTGIPAVSSISR-SHREKPSVFYQQELPDN-----TLRVSA-SPRPADQKT
GTPIG----PSGSYSLGEKPVILYQQSSPGAPQPKGILKVFASPG--------PA----D
LKTEKSALSP--AFYSLGEKPIIFYQQTLPDSELTKESVKISVVPKPTDQKTGISSPVTS
SSYSDREKNIISYQQE-SPDSHLPEKAEKVSLVSG-QVYQKTAIP---------------
----------------------------------TVPSPPYSY---P--SVYYDEVFSD-
-LNKEGSKVLGVVGPAEKKTGIQIVSSTPYSKREKPVTSYQQVSSG--LNEEDLKVLGVA
GPSDQKSEV---YIVPSPTYSQGEQSFISYQPYQEQPDLPKVASKTV---EVSGPAG-QK
PRIQTVSSASYLRGEKPI------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------FHDTLSIS-TVPEP
TYIN-----TGIPVPLSSSSLHREKSNT--FYPQELPDRYLTEDALKVSTIPEPTDQKMV
LPASPPIAFSHSEKQNIFYQKDVPGTHLTEDALKVSAGLRQADQITELPIVSPGNYLPD-
---EKHKLV-SEH-VQRLTHNLNSS-D---SSVRPNN--MPLNSQINDG----VVTQPVS
SGFG----DTSF---EEIQGTEN--TSSKTLKEIQTLL-ME-AENIALKRCNFSA--PLI
PFRDVND-I--SLIQSKKVVCFKEPPT-------------REPF---TEENSN-SRYTQK
DTDTQ--TSLKCKRGI-ENWEFISSTTI--RNPLQEAESK-ARVALD-KTLRQYEVA-KS
VLR-SEPEGY-SGTIGN-KIIIPMM-TIIKSESS-SDASD-GNASCSWDSNLP----ESL
ESVSD-VLLNF-FPYASSKAS-LTD--SREEEGVSESEDG-GCSVDSLGAHVRNLLQCES
SLNHAKQILKNAEEEEYRVRK--RAWNLKFNLADD--RGYSISELNEDDRRKVEEIKAKL
FGHCRTPDLSEGLQSPRGIGCTPERVCGHIIIESHEKGCFRTLTA-EQPQLDSPSCV-FR
SAEPSEVIRG-RRCPSPWRARHISFSK-SLDQDNSHFKVWNSLQLQSHSQFHNS------
ISKGFQVPSC---EKPDHWPSELV-----EPACV--------DFHSSTQIPTPEPMR--Q
FTTSITFSSHRHSKCISDS--SVFKVGVTES-SQGTGASVGVFNSSVTEEQTPPRDLKQK
TSSPSSLKTLNHSADK--DVTVVPEGNRQSEKSPVDFDHSHQEEKLLERSDFKVSPSKPR
SSANCSNFKEVQFSDNH-TLISMSRPNSTL---------GVKEKS--VTPDLPSLIFLEQ
RELF--EQSKDPHADHHVGKHHSLP-------CPNVPSCIFL--EQRELFEQSKPPHI--
-DHEMRENHSSFPHCQDYIASELPPCIFLEQH----QS-KAPSVDDHVKKDHFFISQGQD
CVVGK-N-KHSPKSHISN-VNVEANFSNVTSQLPSDHYTLATS--ASAPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRLYSLDPASKTKMNSEFNCDLQT----ISSRSLDPASKLLTS
KSVAQSQESLGFLGPKSPLDLQVVQSPLPDS-NTIAQDLNTVPSQNSQITTSREIQVNIS
DLEGYSKPE--GTPVSADRLPEQSK-TQVSAFSGKLS-SDAVTQITTESPEKTLLSSEIF
INAKDHGHEILEPTTQ--------KFASSSSVQQITSNRGT-------------------
---DAQPVLLPYKPSGSPKMYYVPQLGTVPPIL--ESKSESTIESSHSGSNDAIAPDFPA
QVLGTRDDDLQ--------------------------------------FTVNIKHKEGI
YSKRAVTKKGKK---PSRFALKVQHPDR---CSL-DNKKDRRNQRTKDIFSQGVKTKTAS
PEEKESLQKDTAG----------TQVQDTKVENLPDTKAT---KQNEI------------
---------------ESECHSEFENTTHSVFRSAKFYFHHPVHLPSDQDTCHESLGRN--
---VFMRQSWKDFFQHHSDKHKEHPGLSLPYQNVDK-------NKTDYTRI-QSLSINVN
LGDK----EVIHTTKSQ-GRDHPKSNVQINDS--QKDRKITSELTTPHTVGLNELWNKYQ
ERQKQQKPPG-----VSDRTELSLVERLDRLAKLLQNPITNSLQA-SESMRDDSRGERDI
KE-WSGKQRQPKSKLQK-KQYKSPEK-GHRNISDRKKHKVLS----------AYQTGSPN
QIKIEQIKFDKYILKRQPCFNS-VSNTSSDSRP-SEE-SGLLTDTPTNILSTTP-SVDSD
MLTQTDREVTL-HERSSSISTIDTARLIQAFGHERVCLSPRQVKLYSSITNQRRRYLEKR
CKHNKKAFNTGHPQMTSEHTRRRHIQVAHHI-SSDSM-SSASSFLSLNSTLCNEKNGPML
NKGVQ-AGNLEIVTGA-KKHTRDVGVTFPTPSSSEARLEEDSDV---------------T
--WSEEKPEEKKLFTDYRGDKKLRKNKPISYEGVSWFVPVENVKSGSKKENLP-KNYGPG
ISWFEPVTRTKPWREPLREKNWQGQRMGGQG----PVADQGGEDGQGPPRPFVKATLQES
LQLHRPDFISSSGERIKRLKLIVQERKLQNMLQSERDVLFNT----------VHPLPRRV
YLAAQKKKPIGKKEMIQRSKRI-YEQLPEVRKKREEEKRRSEYKSYRLRAQLYKTKVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEEEAEEKEEEATAAAA------------AAAAAAAAAAAANLD
DVVVVEEVQEEAGREL---DSDS-HYGHQHLESTDDEEEEEDEEAKAWLQAHPGRILPL-
------------PSPPRH----RYSECERTSLEK-------IVPLTCHVW-QQILYQGNS
RTQISDTNVVCLDTTAQQGSGDDQKTESWHCLPQEMD-SSQTLDTSQTRFKVRREDTEVS
DFPSLEEGV-LTQSENQVKEPN--RGLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFASD
SLFHQSELSFAPLRGIPDKSEDTEWFSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTTVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDSYD-DLCSYMSWKTQKDTQQP
ETNLADKDQVSVATFSDITDENITAKRSDHFDAAYSYGQYWKEEASPKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDVITLDGLNE-----NAVV-CSER---ITEL-------------------------
------------------------------------------------------------
--------------------------QRKLTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDASKGG----------------------IAKVTDS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLTVSSLL----ET
TTGQHT-DTLNQRPLADTHLTEETLKVTAIPEPAYQKTATPTVLSSSHSHRGKPSIFYQQ
GLPDSHLTEEALKVLTVPGPTDQTTGLPTLTSTSYSHREKPGIFYQQELPESNLTEEPLK
VSAAPGPVEQKTGIPTVSSTSQSHGEDLLFFYRQTLPDGHLTNQALKVSAMSGPADQKTG
TATVLSTPHSHREKPGIFYQQE--FPDSHQTEETL-KVSVTPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYPHV-LADSHLPEEGLKVSA-VAGPADQKTGLPTVPSNAYSHRE
KLLIFYQ-QALLDSQLPEEV-LKNSAVS-----GPADGKTGTPTVTSTSSVSSSLGEKPG
AFYQQTLPNSHLTEEALKLSVVPVP-GDQKTGIPSAPSSFYSQREKPIIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSIFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPLGSFSHRENPSIFYQQELPDSHPTEKAVKVS-TGPGPADQKTEIPTV
QSSSYPQRE-KPGVLYPQVLSDSRLPEESLKVSAF-PGPADQTTDTPAVPSSFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGPADQKTGTPTVTSTFYSQYREKPSI-S
HQQALPGTHIPEEAQKVSAVTG-PGDQ-KTWIPRVLSTFYSQREKPDIFYQQTLPGSHIP
EEAQKVSAVPGPADQKTGTPTPTSTS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAY---------------------------------------------
-----------------EPVDQ-TT-G---TPAATSTSYSQHREKPRI-FYQ-QSLPS-S
HLTEEAR--KVS-AVPGP-VD-QK-TG-TPT-STSTFY-SH-TE-KP-GI-FY-QQV--L
PHS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VAYEPVDQTTG-TPT----ATSTSYSQHREKPSIFYQQSLPSSHLTEEAK
NV------SAVPGPADRKT-GIPTLPSTFYSHTEKPGI---FY-QQ-V-LP-HS-H----
LPEEALKVSVAPGP-VD-QTIGITTVT-SPSSSFGEKP-IVIYKQAFPDGHLPGQSLKVS
VAPG-PVDQTTGSPTVTSPSYSQHRAKPGGFYQPALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSYSLGEKPIIIYKQAFADGHLPEEALKVSIVSG--------PS----E
KKTEIPTGPL--GSSALGEKPITFYQQALLDSPLNKEVVKVSAAPGPADQKTETI-PVHS
TPYSNRGKPVIFYQQT-LSDSHVPEEALKVPPVPG-PDAQKTETPSVSSSLYSHREKPVV
FYQ-QALPDSQLTKEALKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NTSYQKELPDS
HLTEKSLKVSDVPGPADQKSGLSTVTSTSYSHREKPIISYQQELP--RFTEAGLKILRVP
GPADQKTGI---NILSSNSYPQREQSVISYQEELPG--LTEVTLKAV---GVPGPAD-QK
TGIQIASSRSYSNREKPSIFHQQELPD--VTEEALNVFVVPGQGDQKA-EVPTVPLSYYS
HREKPSVISQ--------------------------------------QELP--DSHLTE
EALKISPVSIPAEQK-TGIPIGPSSSYSHSHKEKLKISTVHIPHDQKTEFPAATLSSYSQ
IEKPKISTVIAPNDQKTPSQTAFHSSYSQTVKPDILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRRVTEDVLKISTIPGPPSQKTV
LPTALPSSFSHREKPGIFYQKDSPDRRLTEDALKISSAFGQADQITELHTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DLGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NGDLL-QGQPF---TEESPS-SRCIQK
DIGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRRYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTADLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EQPQLDSHSCA-FR
SAEPSEMTRG-RQSPSSCRAKHVNLSA-SLDQNNSHLKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFH---EKMNPWLSELV-----EPAFVPP---KKVDFHSSSQMPSPEPMK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
TSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLPVDFEHSCQEEKPLEMSDFTGNHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVGRSSSRLGVKEKNVTVTPDLPSCIFLEQ
RELF--EQSKAPHTDDHVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFKQCKAPHV--
-DHQMRENHSPLLQGQDSIASDLPSPISLEQC----QS-KVPGIDDQMSKHHFPLPQGQD
CVMEKNN-QHKPKSHIS-SINVEAKFNNVVSQSAPNHCTLATS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRCHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVVQDQESLGFLGPKSSLDFQVIQPSLPDSN-TITQDLKTIPSQNSQIVTSRQTQVNIS
DFEGHSNPE--GTPVSADRLPEKIK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEITEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTIESSHSGSNDAVAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLRNENADASVQVLITGDENLSDKKQK-EIHITRAVTEAAE
AKEKESLQKDTADSGDAAAAVHSAQVEDPEIKNSPDTKAI---TQKEEI-HRKRTVP--E
EAWTSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGRS--
---VFMRHSWKDFFQHHPDKHREHICLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVTDTTKSQ-ARDYPKYSGQINDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQKRQPE-----WGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHNDSRGERDV
KE-WRGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKTKVLS----------HHRAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSSTTSTVESD
ILTQTDREMAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLMTSEHTRRRRIQVANHVISSDSISSSASSFLSSNSTFCNKQNAHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPTSSEAKLEEDSDV---------------T
S-WSEEKREEKLLFTSYPGDRKLKKNKKNSHEGVSWFVPVENVESGSKKENVP-KTWGPG
VSWFEPITKTKPWREPLREQNWQGQHLDGRG----SLAGPGREDGRDPLKPFVRATLQES
LQFHRPDFISSSGERIKRLKLIVQERKLQSMLQSERDALFNIDRERQGHQNRMHPLPKRV
FLAVQKNKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKVSGSS
VYSGMDQVYWGKEKWRKHVAS-----------------------------

MEPEDLPWPGELEEEEEEEEEEEEEEEEA----------------------AAAAAANVD
DVVVVEEVEEEAGREL---DSDS-HYGPQHLESIDDEE---DEEAKAWLQAHPGRILPP-
------------LSPPQH----RYSEGERTSLEK-------IVPLTCHVW-QQIVYQGNS
RTQISDTNVVCLETTAQRGSGDDQKTESWHCLPQEMD-SSQTLDTSQTRFNVRTEDTEVT
DFPSLEEGI-LTQSENQVKEPN--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFAPD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHPL-
IGSTAVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDRYD-DLCSYMSWKTRKDTQWP
ENNLADKDQVSVATSFDITDENIATKRSDHFDAARSYGQYWTQEDSSKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
V-ESDVITLDGLNE-----NAVV-CSER---VAEL-------------------------
------------------------------------------------------------
--------------------------QRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDTSKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLAVSSPL----ET
TTGQHT-DTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQ
GLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLE
VSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTG
TATVLSTPHSHREKPGIFYQQE--FADSHQTEETLTKVSATPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYPQD-LADSHLPEEGLKVSA-VAGPADQKTGLPTVPSSAYSHRE
KLLVFYQ-QALLDSHLPEEA-LKVSAVS-----GPADGKTGTPAVTSTSSASSSLGEKPS
AFYQQTLPNSHLTEEALKVSIVPGP-GDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVS-TGPGPADQKTEIPAV
QSSSYPQRE-KPSVLYPQVLSDSHLPEESLKVSAF-PGPADQMTDTPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGLADQKTGTPTVTSTSYSQHREKPSI-F
HQQALPGTHIPEEAQKVSAVTG-PGNQ-KTWIPRVLSTFYSQREKPGIFYQQTLPGSHIP
EEAQKVSPVLGPADQKTGTPTPTSAS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAS---------------------------------------------
-----------------EPVDQ-TT-G---TPAVTSTSYSQYREKPSI-FYQ-QSLPS-S
HLTEEAK--NVS-AVPGP-AD-QK-TV-IPI-LPSTFY-SH-TE-KP-GV-FY-QQV--L
PHS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VASEPVDQTTG-TPT----VTSTSYSQHTEKPSIFYQQSLPGSHLTEEAK
NV------SAVPGPGDRKT-GIPTLPSTFYSHTEKPGS---FY-QQ-V-LP-HS-H----
LPEEALEVSVAPGP-VD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPEGHLPEESLKVS
VAPG-PVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSG--------PT----E
KKTDIPAGPL--GSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETL-PVHS
TSYSNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSYREKPIV
FYQ-QALPDSELTQEALKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NISYQQELPDS
HLTEEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELP--HFTEAGLKILRVP
GPADQKTGI---NILPSNSYPQREHSVISYEQELPD--LTEVTLKAI---GVPGPAD-QK
TGIQIASSSSYSNREKASIFHQQELPD--VTEEALNVFVVPGQGDRKT-EIPTVPLSYYS
RREKPSVISQ--------------------------------------QELP--DSHLTE
EALKVSPVSIPAEQK-TGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQ
IEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPVSLSSSYFHREKSNI--FSPQELPGSHVTEDVLKVSTIPGPAGQKTV
LPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DVGS---EEIQDAEN--SAKT-LKEIRTLL-ME-AENMALKRCNFPA--PLA
RFRDISD-I--SFIQSKKVVCFKEPSSTGVS--NGDLL-HRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCRRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNMKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EHPQLDRHPCA-FR
SAGPSEMTRG-RQNPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFD---EKMDPWLSELV-----EPAFVPP---KEVDFHSSSQMPSPEPMK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
TSSPSSFKMHSNSQDK--EVTILAEGRRQSQKLPVDFERSFQEEKPLERSDFTGSHSEPS
TRANCSNFKEIQISDNH-TLISMGRPSSTLGVNRSSSRLGVKEKNVTITPDLPSCIFLEQ
RELF--EQSKAPRADDHVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQMRENHSPLPQGQDSIASDLPSPISLEQC----QS-KAPGVDDQMNKHHFPLPQGQD
CVVEKNN-QHKPKSHIS-NINVEAKFNTVVSQSAPNHCTLAAS--ASTPPSNRKALSCVH
ITLCPKTSSKLDSGTLDERFHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVAQDQESLGFLGPKSSLDFQVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVFADRLPEKMK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEIIEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAIAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLQNENADASVQVLITGDENLSDKKQQ-EIHSTRAVTEAAQ
AKEKESLQKDTADSSAAAAAEHSAQVGDPEMKNLPDTKAI---TQKEEI-HRKKTVP--E
EAWPNNKESLQINIEESECHSEFENTTRSVFRSAKFYIHHPVHLPSDQDICHESLGKS--
---VFMRHSWKDFFQHHPDKHREHMCLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVMDTTKSQ-VRDYPKHNGQISDP--QRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERSV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKSKVLS----------HHRAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSGTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRHIQVANHVISSDSISSSASSFLSSNSTFCNKQNVHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPSSSEAKLEENSDV---------------T
S-WSEEKREEKMLFTGYPEDRKLKKNKKNSHEGVSWFVPVENVESRSKKENVP-NTCGPG
ISWFEPITKTRPWREPLREQNCQGQHLDGRG----YLAGPGREAGRDLLRPFVRATLQES
LQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDALFNIDRERQGHQNRMCPLPKRV
FLAIQKNKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

------------------------------------------------------------
---------------------------MEPGEEVE------DEEEE--------QSVPP-
---------------------------------------IATTP-PRRSWREESLSQSSS
ETQASAASGISLGEAIRQRTAVNQEIDSWYQLPGEVD-ASRLTAASETKLGLASDRNDLT
EFPTLEEGV-LPSAETSRRQHT--EDTVHGLLLDIQDSQLSPCLPLLMYSTPGQ-RILDE
TLFQQSERDFIHLRGVPDVSGASEQHSNRLHVPEAAWLTDVETPSDAPSDCYSLSQHPL-
SFRQTEPGDASYLSQQASRFSERLLM----NKKASEDCRNDAN-----------------
-----E----------------------------KSSIPHMGDKAMN-QTEASLAKQTCG
TSA-------------------EDACFTCN------------------------------
------------------------------------------------------------
-------------------NNVLAPVFELSEKEKELLRR------------------DEF
SSSENSSCKAALTKNSGKSE----------------------------------------
------------R-------------------------------------EMQMEKVK--
------------------MAESE-----SEGCLRHPER----------------------
--------------------LEK-------------------------------------
-------------------------------------EKAPELGSSKTL-----------
------------------------------------------------------------
-------------------------------------------SDDLKKDSCKNSGAQGV
FS-AKTSEIARESKECRVGLNDFGSMKFVAVTNELQ------------------------
---------------------GAFLDHEAKQGVRE-------------------------
-------------------EELSPIVP------------------SSSDSAPKQLVVTN-
--VESPS----------------------CTENAQV------------EVQPGVR-----
----KAE-----------------------------------------------------
------------------------LTISDVSI----------------------------
--ERGH----------------KVTDIS----PSLNFTVDDGSFFRHFSHPSY-------
------------------------------------------------------------
-----------QSTPGILLKNVKTDPGAHVIKSDV-HAPPLCL-NEDNSG-------NSL
SSTP--TSGEKQRSLQCAQK-ENNKHFDS--LKLK--------------------YPHTG
R------IQSLPSLYFMEKV----------------------------------------
-------------------------------------------------------DT---
----WNMSQ---------------------------------P-----------------
----------------------------ENMSD----------------------ALASR
DQSVISHRKKAYSVVA------------------S------SANNILSMQ---NSSR--N
PEVHVAAPSGETHSLENIHFHDKISERVHPLTR--SQSDNSVHV-ASKNNS---QTDV-V
QPVNREAMQPLEGKSNVSGVPE---NR-LGGAL---------------------------
----------------------------------------------------------IH
------------------------------------------------------------
------------------------------------------------------------
---------KLTTEIASPSVD----KGAEGSSVGQSSY--------P-NA-FI-PSERV-
--------------------------------------------------AHLIKEDG--
--------NSPTDDQKRCDGLENPRLP------HNLDIGHVSVDNVGDISPDSLNLP---
-----------------------------------AC-----------------------
-----------SGESSHG-------------ALGSPVVTRHFFTSA-G----DDNF----
IPSSTATVLETPEK-EE--------------LNIEER--IPIYLRNL-------------
-----GIDQSPGTILTPFVPR-GPI-REVEFSPSDLR-------TLKDST------DTLT
R---------------------TIQQPQGDLLTAVDVIQTSFNSGTSTVSISIPMNSETD
SDTFSPRELSPRFSIPFGEKPKSQC---------TMSCHKVEATTP--------------
----------LSTQWE--------------------------------------------
------------------------------------------------------------
------AECSVVSKLAEPSQHLQTVSPDCHSNRESPMLVAKGVQDL--LAKKELKD--VS
GSSQRWTAS-----------------------------------------SSAGVKDEQG
RGSQTSSEGSEKNKAQESDY----LIG----SGAL-------------------------
-----------------------QEIRKLLAEAE--------------------------
------NIAGSWHD----------------------------------------------
--------------------PVFSNASSTETES-SPVQMEKEDGTKDSELVKDS-IPPLQ
KVM---------------------------SWAESMNQRSIHEGS-----IT--------
-------------KPQDSCKDDLKW------ERSFDGGLCSREDVVEMTREFRTGKSVGR
SEPEGCSSVTTDRNLPAVVAVAQSSANSEFSTERPSELGSPSP-SEPQG---SVINVPAS
FQSKLSKANVAVSTAGGIRESSGSSSGDSLAAHVKNLL-GN----------------PLM
LLGRTAD-IS--------------------------------------------------
-----------------GGFQSMMSKTS-------AAG----------------------
----SKAEGV-QESHGS----------------------SSGDSLAARVKNLLGDPSETL
GSTTD-VPGGFQSVLSKPSAA------GSKAGGVQESD--GSSSADSLAARVKSLLRNGS
PLMPATPILRSSDEEERKARA----W-VKLKLANR--SQEAVLDLSEEDRQRIEEIKAEL
LLSAKKSGQAKGTRSYSSLAAS-VYSCNQEADEEHSKASSDK-----RFHSDSQTQA-FR
TKELLEPSLQ--HVVPLYRAELSDCCL----LKNTQLKSLSTAEPPTCSQHQA-IASSRS
GCVGLHLPLE---KQQDTRVMSFAAASDAQTAKVPSPAQKKLSFPK-----CSEEMS--K
QITSITFSSRRRFQSPLTS---VVLDGFFSGD-DLDEIMPLEMDSVTTEEQSHGKQHWER
----------------------------------------------SETCPLSG--SAP-
---AGSQSNEIAFTADKDRFHDVSADGNRA---------GAYQETDCLSDREPVTVCADE
RQTPSAKNLDTPSQDVTELDRHSAR-------LLGLDCDRRFSQGMKGLHESHSI-----
-SSYQQEKSSPTSHIQLCES--------LEGS--------DPAIQTDLPKDHGKLLE---
-----EE-KCPSDAVPFI--QKEV-SGEQI-DAHQHSDEILPT--MSPSSPIKKVLSCVH
ITLSPKCNNSE-------LHRDLNTENEMRLEDKLEVNSQPVPLKTPETLLQADPKLPTA
DLIPEDQRCSSFPVPSSDP------CSVF---------SSVPSTAGQELLLHG-------
-SEKLQ------AMSSGGCSLKNICSCTDPAKSRKST-SDATTQITTESPGKTTFSAEIY
VNSQDIESSAHQSSTQ-KAKEFPQNTAS--SLNRTSSFPRQ-------------------
---GGQPLLLPYKPSGSTEMYYVPYLKAGAKIS--PL------GSENNGSNDALPPGLPA
NVLGIQDDKPP--------------------------------------DTTAIKHKEGV
CSERAKPKLAWA---EEQMIAQEGAPG---------------------------------
------------------------------------------------------------
-----------------SHRLKSVNATHSVFKSAQFYLHHPVPTCENY-LLSNSELSEDS
SGVGHTGISSSTVIQNRKKAHRHRRVFSAHHKKDGEREFFPLTAEADYSKN-EDLNVDTS
LNNETPGEELLQRGRRE-ADQMAACS-QMSNLRENVVKDLPLRQRTHSAGSLDELWVKFL
ERQKRYQQHH-----FRRNGELTLVERLDRLARVLQNPIRYTLI-PAKSERSASENTSEV
KE-------QEKIRLPEKSMAESTLG-PHAAR--VKERPRINCRERSFVELRKDRSGEKV
-------TCHTNEISEHRQYLDTCSDTCSETRL-S---KDL----CTTISSTIS---ESD
AVTQTDIETTTQTEVSSSVSTIDTARLVRAFGHRRVQVSPRLSQLYHTIHQ-QKSRSEKW
DEESSGVRDVEHPKVASERHRK----QKETQKALDPA-LTSSGSWGPSSALSNKRRARML
NKGIQ-AGDLEIVNGATKKNTRDVGVTFPTPRSIQPNQRPRDPWHRVDGIFGESDGMVTD
HQAAGSK-------------------------GISWFVQAEDLKFESRKENRSNSIPGPG
SSWFEPFTTTKPWREPLREKNFQEQQYSKV----TQSAVPERDAETRPTRPTVKLTLQEA
LAVHRPDFISRSGERVKHLKLVMEERRIQSALQSEQEELFNPPEKRKGYRNASHVLPGRG
HLIKEKRRAIPKSEMVQRSKRI-YEQLPEVQKKREEEKRKSEYNSYRLKAQLYKMKITNH
VLGR--KVPWN---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------MPPPRF----SFARGERTC-----------------------------
----------------------AQKTESWQCHPQQRD-SYQTTNASQMEINVDLKGNEVT
DFSSLEEDL-LIQSEDEVKERS--RNLLCSPLLVIQDSFASPDLPLLTCLAQDQ-EFGPD
SLFHQSELDFAPLRGIPDKSEDAEWFSRPSEVSEALFQATLEVPPDFINLS--ISQHSI-
T-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------EGLQGK
A-DSDVTTLDDDTECCCLEEKAVVCSES---VAELP------------------------
-----------RESCDQHDVTGECVHLATSEDLLD-------CDSPQHWQPTLQQPPEEE
STFKKPVGHSNLGINYPFPCILPEFIPYEPIRESEHSSSNLRMLRFSPDTVPKSLKHLS-
GDTSKED----------------------LAA----------------KLQSGIP-----
----TSG---------------------D--SDFGSNLSLSSEDLPQLAISSQK-----N
TTGQLI-DTVKQNTLPVIHQTAASLKVSHFTELPDQKTGLPIEPSASYSQSEKPNILYRE
GLPDDHLTDQSLTVLAVLGPDDQKTDTTAVSSF----SSHKGKPYQQELPSSYLT-----
------------------------------------------EEALKVVAVPGTPDQKTG
RPTVITTSYPHREEPGIFYQQE--LPNG----DTP-KVSGVPGPPDQKSRT------PRV
TPTP-YLQSKKPS-SLYQDS-LPDGHLPEESLKVSS-FPGSVDQKTGIQTII---YPQID
KPDFFYQ-QALPDNHLTEET----------------------------------------
------------------------------------------------------------
----LKVSVAPKPAEQKIGIIPVSSTSYSHGEKSHTLNLQVLPESHLTDKNLEVLAIPGI
-ANQKA-RTVPVSSTSSLLRE-NNILYQQELPQSHLTEETLKIS-TAPRPDDLKTGILT-
HSGFYSQREKPG-IPYQQTLSDIDTTKETLKASAF-YGLTDQKTCTPAVSS-IFHSHREE
PSVYY------QQELPDSHPTEKC-LEESVVPGPADQKSRIPTV-TSVSYSHRDKPG--S
YQQVLSDSHLHEDTVKVSAISE-PADQ-ISGIPTLTSA----------------------
-------------------------S-------YS-YK-EK-PS-IF-YQ-CKL-LD-SN
-LER-AL--KVSSAP-QAAE-LKIG-TPIV-FSAS-YSQI-DKPG-VFS-MPA-VLK-SH
-QTE-DIL-KV-SSV-PGP-DQ-KG-GI-SAV-TST-ST-LYRKEPGI-SSQ-QELPE-S
Y--------ISR-DFPRP-AD-QK-PG-TPA-GPSDSS-SL-GK-KP-II-FY-QQV-L-
PSS------------------------------------------------CQPEE-A-L
K-VLAA--SGTV-GQ-K-TG-TPA-VS-SASYSQIDKP-AV-FCK-EVL-LK-SHQT---
------------------------------------------------------------
------------G--PDQKGGISTLTSTPTSHRREP-G-I-SS-QQ-E-LS-ES-Y----
VPRESPKVSASPRP-AD-QKTGAPAGP-SDSYSLSEKP-IIFCQQVPPSSHLPEEALKIL
VASG-TAEQKPETPTGPSDSY-SLGEQPIIFCQPVLPSSHLPEEALKVSA-DSTIAEQTP
ATPAG----SSGSYSLGEKPIIFCQQFLPGVLQPKGILKAFASPG--------PG----D
LKTERSTISP--TFYSLREKPITVYQQAPPDSELTKEGVKFSVVPKPADQKTGISSTVT-
SCYSEREKNIICYQQE-LPDSRLTE---KVSLVPG-SVCRKTETQTVSSHSYSY---STG
FYE-EVFPDT--------------------------------------------------
--NEKASEVLGVLGPVEKKTGIQIVSSTPYSNREKPVTSYQKVLSSPN--GEALKVVGVP
GPSDQKTAL---YAVPSPTYSQGEQSFIYYQPYENLPDLPEEASKTK---EVSGSAS-QK
PSIQTVSSASCSHGEKPSDFHQQELPN--ITEGALYV-----------------------
------------------------------------------------------------
------ILPGTDGQK-FRIPTTPLSFYLP--EEKSKISTVNIPEDQKTESPITTHSSYLQ
KEKPKISPVIALNDQTTPSLTVFHSLHSQRIKS----QQQMPD---SGDTPKIS-TVPEP
TYIN-----TGIPVSLSGSYLHKEKCNT--FYPQELPDRYLTKDALKVSTIPEPADQKVV
LPTS-ATSFSYCEKRNVFHQKNVPGRHVTEDVLKVSTRLRQADQITELPVVSPDTCLPD-
---GKHKLV-SEH-VQKLLNNLNSS-D-----VRPND--MPLHSQVDDG----VVTKPES
SGFG----DTGS---EEIRGTQN--SSKT-LKEIRTLL-ME-AENIALKRCNFSA--PLI
PFRDVND-I--SFIQSKKVVCFKEPPTIDIS--NGDTL-QREPF---TEDNPN-NRYIQK
DIGTQ--TSLKCQRGI-ENWEFITSTTI--RNPLQETESK-SRVALE-ESLRQYEVA-KS
VLR-SEPEGY-SGSIGN-KIIIPMM-TIIKSETS-SDASD-GNASCSWDSNFP----ESL
ESVSD-VFLNF-FPCASSKAS-LTD--SREEEGVSESEDG-GCSVDSLGVHVRNLLHCES
SLNHAKQILKNAEEEEYRVRK--RAWNLKLNLANN--PGYSISELNEDDRRKVEEIKAKL
FGHGRTPDLSEDLRSPRGIASTPEPVCSHIIIESHERGCFRTLTP-EQPQLDSHSCV-FR
STEPSEVIRG-QPCPSPWRTRHINFSK-SLDQNNSHFKVWNSLQLQSHSQFHNN------
ISKGFRAPSY---EKSDPWLSELV-----GPACV--------DFHSSTQIPTPEPMR--Q
FTTSITFSSHRHSKCISDS--SVFKVGVTES-SQGTGASVGVFNSNVTEEQTPPRDLKQK
SSSPSSLKTLSHSPDK--DVIIVPEGNRQSKKSPVDFQHSHEEEKLLERSDFKVNLFNPG
SRANCSHFKEVQFSDSH-TLVSTSRPNSTL---------GVK-ENITITPDIPSLIFLEQ
QELF--EQSKDPHADHHQQKHHSPP-------CPNVPPCIFL--EQ-ELFEQSKLPHIEH
VNHEMRVSHSSFPHCQDYIASDLPS-IFFKQH----QS-KIPSVDDHKKKDHFPLSQGQD
CVVEK-N-KHTPKSHVSN-TNVEAKFNNAVSHLSPDHYTLATS--ASAPPSNRKALSCVR
ITLSPKTTSKLDSGTLDKRFYSLDPASKTRMNSEFNSDLQT----ISSRSLEPTSRLLTS
KSVAQNQESLGFLGSKSSLDFQVVQSPLPDS-NTIAQNSNTVPSQNSQITTSRQIQVNIS
DLEGYSKPE--GTPISADGSPEQNK-TQFSAFSGKLS-SDAVTQITTESPEKAVFSSEIF
INAEDHGQEILESTTQ-KLQKVPVRFASSSSVQQITSNCGADETEVILDLPLYSMGKNKK
HGGTAQPILLPYKPSGSPKMYYVPQLQAVHPML--DSKSDTTIESTHSGSNDAIAPDFPA
QVLGTRDDNLS--------------------------------------STVNIKHKEGI
YSKRAVSKASLS---VGKKIFEKDNAEASVQVSITGDENLSDKKQEEDIFSQGIETKTAR
PEEKESLQKDTAGTSDTTPAEHPAQVQDTKVEDAK----------QNET-DIKGNIP--K
EAWTEEKESLHIDISESECHSELENTTHSVFRSAKFYFHRPVHLPSDQDTCHESLEQS--
---IFMRQSWNDFFQHHSDKHKENTCPSPPYQNVDK-------TKADYPRI-KSLSINVN
LGDK----EVICTTNSQ-DRDHPKSNIQINDS--QKNCKITSELTTQHTMSLNELWNKYQ
ERQKQQKPPG-----VSDRTELSLVERLDRLAKLLQNPITKSLQA-SERVQDDSREEQDI
KE-WTGKQKQPKSKLQK-KRYKSPEK-GHKSIGDLKKHKVLS----------ANQTGGPN
QIKIEQIKFDKYVLKRQPCFKS-VSNTSSDSRP-SEE-SGLLTDTPTNVCSTST-SVDSD
MLTQTDREVAL-HERSSSISTIDTARLIQAFGHERVCLSPRRIKLYSSVTNQQRRYLEKR
CKQNKKPFNTGHPQMTAEHTKRKHIQMSH-YISSDSV-SSASSFLSLNSTLCSENHKHML
NKGIQ-AGNLEIVTGA-KKHTRDVGVTFPTPTSSEARLEEDSDV---------------T
S-WSEEKIEEKKLFTDYLGDKKLRKNRPISYEGVSWFVPVENVKSGSKKENVP-KVYSPG
ISWFEPVTKTKPWREPLREKNWQGQHMNCQG----SVADQGRDDGRGSPRPFVKATLQES
LQFHRPDFISRSGERIKRLKLIVQERKLQNRLQSERDALFNS----------TRPLPRRV
FLAAQK-KPVGKKEMIQRSKRI-YEQLPEVQKKREEEKRRSEYKSYRLRAQLYKKVYPAR
NHRK--TSRMRLDTMTRSQEPEA------RNTERSTPKMNRRV-WGRISV

MEPEDLPGPGELEEEEKDVEEEK-----EEEEKTV---------EAAAVEEEP----ATS
VEIVTEEVEEEAGPEL---DSDS-NYEFQSRESSDEE-DREDEEAKAWLQAHPEVILLP-
-----------PP-PPRY----SYVRSARTCA----------------------------
----------------------EKKTESWQYLPQEIN-SSQTLDASQTGINVKLKGNEVT
NFPSLEKGV-LIQSEDQVKEPN--RDLLCSPLLVIQDTFASPDLPLLTCLTQDQ-DIGPD
SFFHQSELDFAPLRGIPDKSEDTEWFSRPSEVSEALFQATLEVPSDFVNSCFSISQHSL-
TEGLQGKA----------------------------------------------------
------------------------------------------------------------
----ESDVI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------TLDNDTECCSLDEKAVVSSE---GVAELR------------------------
-----------RETCDQYDVTDECVDLATLEDLLD-----DLCDSSLHLEPTLQQPSEED
SNFEKLVGHSNLGINQSFSSVLPPFILHEPTRESEHRSSNLRMLRFSPDTVPKSLKHLS-
GDTSQED----------------------IAEIIQS------------KLQSGIT-----
----TSG---------------------D--SDIGSHLSLSSEDLPQLAVSSHK-----N
TTGQPI-NTLNQKALPDSHQTAASLKVSHITELAEQKTGIPTEPPLSYSRVEKPNILYQQ
GLPDGHLTDQLLTDSVVPGPADQNTETATVPSPSYSHRDKPSIFYQQELPGSYLT-----
------------------------------------------KEALKVSAVPRAPDQKTG
IPTVSSTSNSNKEEPGIFYEQD--LPESHLIEETP-KVSGVPGPPDQKSRT------PHV
TSTS-YLQRKKHS-SLYQEG-LPDGHLPEQSLKVSA-VPESATWKTSIQTITSPSYSQKD
KPDLFYQ-QAFLDSHLTEET----------------------------------------
------------------------------------------------------------
----LKVSVASKPADQKIGITTVSSNSYSHGEKSHTLNLQALPESHLTAKNLKEPILPGF
-ADQKT-EIVAVSSTSNSLRE-NSIFYQQELAQNHLTEETLKVS-TAPGPSDLKTGILTT
HSGFYSQRGKPG-VSYQQTLSDIYTTKEPLKASPV-YGLTDLKTGTLAVSS-VSHSHREK
PSVFY------EQELADSHPAEKS-LEESVVPEPADQKTSISTV-TSISYSHREKP-I-S
YQSVLSDSHLPEETLKVSAVSG-PADQ-ISSIPTLTSA----------------------
-------------------------S-------YS-YK-EK-PS-IF-YE-DKL-LD-SN
-LEN-AL--EVSSA----------------------------------------------
------------------------------------------------------------
---------------PGP-AE-QK-IG-TST-VSFASY-SQ-ID-KP-GV-FY-KQA-L-
LKS------------------------------------------------HQAED-I-L
K-VSSA--PGPD-NQ-K-DG-IST-VT-STSYS---------------------------
------------------------------------------------------------
-------------------------------HKKDP-G-I-SS-QQ-E-LP-ES-Y----
IPRDSSEVSGSPRP-AD-QKTGTPAES-SNSYSLGEKY-VIYYQQVLPSSHLPEEALKVL
ADSS-TAEQKTGTPAGPSDSY-SPGEKPIIFYQPILPSSRLPEEALKVLA-DSAAKEQKT
GTPAV----SSGSYRLGEKPIIFYQQSLADGHLPKGVLKVFASPG--------PA----D
LKTEKSTVSP--TLYSLGEKPIIFYQQALPNSEVT-KGVKISVVPEPADQKTEISSTVTS
SSYSDREKN-ISYQWE-LPDSRLTEKAEKVSLGSE-PVNQKTGTPTVLSTSYSY---PSV
SYE-EVFPDL--NEESSKVLGVVGT-DEKKTGIQIVSSTPYSNKEKP--SVSYKEVFPD-
-LNKEALKVLGVLGPAKQKTEIQIVSSTPYSNREKPVVSYQQVLSG--VNEEALKIVDVS
EPSDQKTGI---YIVPSSTSSQGEQTFVSYQPYEELPDLPEVASKTA---EVSGPAN-QK
PRIQTVSSVSYSHEEKPSVFQQQEVPN--ITEDALNVVVLSGPDDQKI-RVPTTPFLSFY
SHKEKPSVSSPQEFPDSYLTEEALKISAVFLPAEQKAGTRTGPFDSSFHGVK--PSDLTE
ESLKDSAVARQADQT-NRVPTLPSNFYSH--EENPKISTVNAPDDQKTESPSTTHSSYLQ
KEKSNISTVIGLNDQTTPLQTVFYSSYSQRVKP----QQQLPDRVQSGDTLKIS-AVPEP
TEVN-----TGIPVPLSGSYLHRDKSNT--FYLQELPDRYLTEDALKVSTIPEPADQKMV
LPGSPPSSFLYSEKQNIFHQKDMPDRHLTEDTLKVSPGLRQADQITELPIVSSGTYLPD-
---EKHRLV-SEH-VQRLIHNLNSS-D---SSFRPNN--MPLNSQVDDG----VVTKPES
SGFA----DTGS---KEVQGTAN--SSKT-LKEIQTLL-ME-AENIALKRCNFSG--PLI
PFRDVND-I--SFIQSKKVVCFKEPSTIDVS--NDDML-QREPF---TEENSN-NRCIQK
DIDTQ--TSVKCQRGI-ENWECISSTTI--RNPLQEAESK-ARVALD-ETFRQYEIA-KS
VLR-SEPEGY-SRTIGN-KIIIPMM-TFIKSESS-SDASD-GNASCSWDSNLP----ESL
ESVSD-VLLNF-FPYTSSKAS-QTD--SREEEGVSESEDGGG-SVDSLAAHVRNLLQCES
SLNHAKQILRNAEEEEYRVRT--RAWNMKYNLADD--HGYSISELNEDDRRKVEEIKAEL
FGHSRTPDLSEGLQSPRGIGGTPEPVCGHIIIESHEKRCFRTLTA-EEPQLDSHSCV-FR
SAEPSEMIRG-RQCPSPWRARHINFSK-SLDQNNTNFKVWNSLQLQSHSQFHNS------
VSKGFRMPSR---EKMDPRLSELV-----EPACV--------DFHSSTQIPTPEPMR--E
FTTSITFSSHRHSKRISDS--SVFKVGVTE--SQGTGASVGVFNSNVTEEQTPPRNLKQK
TTSPS-LKTLNHSPDK--DVTIVPEGNRQSEKLPVEFEHSHQEEKLLERSDFKVSPSEPS
SSANCSNFKEVQFSDNH-TLISMSRPNSTL---------GVKEKNITVTPDLPSVIFLEQ
RELF--EQSKVPHADHHVRKHHSPF-------CPNIPSCIFL--EQRELFKQSKPPHI--
-DHPMRENHSSFPHCQEYIASDP-PSIFLEQR----QS-KAPSVDDHMRKDHFSLSQGQD
CLVEK-N-KHMPQSHISN-INVEAKCNNVIYQLPPDHCTLATS--ASAPPSNKKALSCVR
ITLCPKTPSKLDSGTLHKRFYSLDSASKTRLNSEFNSDLQA----ISSSSLEPTSKLLTR
KSVAQNQGSLGFLAPKSPLDLQVAQSPLPDS-NSIAQDLKTVPSQNSQITTSRQIQVNIS
HLEGYSKPE--GTPVCADCSPERSK-TQFSAFSGKLS-SDAVTQITTESPEKTTFSSEIF
VNAEDYGHEILEPTIR-KLQKVPVRFASSSSVQQITSNHGT-------------------
---DAQPLLLPYKPSGSPKMYYVPRLQRVPPVL--DSKSDTTIESSHSGSNDAVAPVFPA
QVLGTRDDDLP--------------------------------------STVNIKHKEGI
YSKRAVTKASLS---VGKKTSQKDKSEASVQVTIIGDENLSDKKQKEDIFSQRVMTKTAW
PEEKESLQKVTAGSSDAAPAADSAQVQDTKTESIPDTKAT---KQNEI--HIKGTSP--K
EAWTEEKESLHIDISESECHSEFENTTHSVLRSAKFYFHHPVHLPSDQDTCHESLGKN--
---VLMEQSWKDFFQHHSDKHKEHTCLSPPYQNMDK-------TNTDYTRI-KSLSINVN
LGDK----EVIHTTKSQ-GKDRPKSTVQISDS--QKNCKITSELTTQHTVSLNELWNQYQ
ERQRQQKPPG-----VRDRTELSLVERLDRLAKLLQNPITHSLQA-SESMQDDSRGEQNI
KE-WNGKQQQPKSKLQK-KRYKSPEK-GHKNIGDLKKHKVLS----------DHQTGVPN
QIKIEQFKFDKYILKRQPCFNY-ISSTSSDSRP-SEE-SGLLTDTPTNILSTTT-SVDSD
ILTQTDREVAL-HERSSSISTIDTARLIQAFGHERVCLSPRRTKLYSSITNQQRRYLEKR
CKHNKKAFNTGHPQMTSEHTRSRHIQVAHNI-SSDSV-SSASSFLSLSSTLCSENNGYML
NKGIQ-AGNLEIVTGA-KKHTRDVGVTFPTPSSSEARLEEDSDV---------------T
S-SSEEKIEEKQLFTDYFEDKKLRKNKPNSYEGVSWFVPVENVKSRSKKENVP-KIYGPG
VSWFEPVTKTKPWREPLREQNCQGQHMDGQG----SVAGRGGDDGRDPLRPFVKATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLENMLQSERDALFNT----------MRRLPRRV
FLAAQK-KPIGKKEMIQRSKRI-YEQLPEVQKKREEEKRRSEYKSYRLRAQLYKKVSGGS
TVS---RAEWIIHLE-----------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MREEGTEVT
DFPSVEEGI-LTQPENQVKKSK--RDLLCSPLLVIQDNFASPDLPLLTCLTQDQ-EFESD
SLFQPSELEFVPLRGIPGKSEDTEW-----FSR---------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------P----------------------------------
-----------------SEVSE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ALFQ------------AASEVAS---DLEGLQ---------GKAESGT
YTLDDDTECCNLDENAVVCSTRVDDLQREPARELEYHSSDLRMLRVSPDTVQKTLEHSA-
GDTSKGG----------------------IAEITQS------------SLKPGIT-----
----TT-R--------------------ES--DTGSLLSLFPEDFPQLALRSPQ----EI
TIGQHS-DTLHQQELVGSHKTEETPKVSTVPKLDDQNTGISTVPSSSYSQRGKPSILHQQ
SLPDSYLAEEALKVAAVPEPTDQKTSIPTVLPGSYSLGEKHCIFYPQTLPESHLT-----
------------------------------------------EEAVRVSAFSGLADQKTD
IPTVLPSSYSLREKHNIFYQQA--LPDSHLTEEAV-RVSAVPGPADQKTRI------HIV
LPGS-HSLGEKAS-IFHQQA-LPESHLTEEAVRVSAAVPGSVDQKTGIPTVLPGSYSLGE
NCNIFQP-QTLPDGHLTGEA-VRVSTVP-----GPVDQKTGIPTVLSGS---YSLGEKRN
IFHPQTLPGIHLTEEAQRVLAVPGP-ADEKTGIPTVLPGSYSLGEKRNIFHPQTLPSIHL
TEEAQRVLAVPGPADEKTGIPTGLAGSYSLGEKRNIFYPQTLPQSHLTEEALKVLAGPGP
-VDQKT-GIPTILPGSYSLGERRNIFHPENLRDSHLTEEALRVS-GVPSPADQKTDIPAG
LAGSYSLGEKRN-IFYPQTLSQSHLIEEAIRVSAF-PGPADQKTGIPTGLAGSYSLG-EK
CNIVH------SETLPDNHLTEGT-QRVLAVPGPVDQKTGIPTG-LAGSYSLGEKRNI-F
HPENLPESPLTEEALKVLAGPG-PADQ-KTGIPIGLPGSYSLGEKHHIFHSENLPDSHLT
EEAVRVSAVPSPADQKTGIPTVLPGS-------YS-LG-EK-CN-IF-HP-ENL-PD-SH
-LTE-EAL-KVLAVP-GLAD-QKTG-IPTV-LPGS-YSLG-EKHH-IFH-TKN-LAD-NP
-LTE-EAI-RV-SAF-PGP-VDQKT-DI-PTG-FPG-SYSLEGEKHSI-FHP-EILPD-N
HLT-EEA-VRVL-TVPGP-PD-QK-TD-RPT-GHPGSY-SP-RE-KH-NI-FY-PQT-L-
PES------------------------------------------------PRTEE-A-L
R-VSAV--PGPV-DQ-K-TG-RPT-VL-PGSYSPGEKH-HI-LHP-ETL-PD-SHLTE-E
SL-KIS-TVP-VP-TDQ-RTE-KII-VPS-AS-L-SQ-REKHVIFSQQQLSDGDLTAQVL
-K-A-S-VA--PGPADQNI-GLPTLSSSSYSLGEKH-C-I-CY-QQ-A-LL-DS-H----
LIEQAQKVAAVPRP-AD-QKTRIPLASSTSYLQGREKH-SIFYQQEFLGSSLIEPAQKVS
PVPG-PTDQKPEIPT-VTSTY-SHVEKPFIFYPQGLPDSPLPEEALKVTA-VSEPTDQQT
GTPVV----PSSSYSPGEKPIIFYPQGLTDSHLPQKALKVSAILG--------PG----D
QKTGLLSEPS--SSYSHREKSNIFYAQEFPGSHLTEEALKVSAFSGIGDQKTGIP-TVLS
SSYSLRGKPIIFYQQA-LSDRHLTDEALNVSASSG-PADQETGIPTVSSVSYSHRERPSI
LYQ-QPFSDNQLAIAALKVSAVSGS-DDQKTRKPTITSASYSEREKP---IIYHQQLPD-
-LTQESLNVFRIPGLGDQRTGITAVTSTTYSHREKPVISYQQELPAPN--EGALKVLGAP
GSADQQSGI---RFGPSTSYSHRKNPIFSYL-E--SPDITEETLKIS---AVSGPGD-QK
TGIHIIPSSSYSYREKDSIFYQEELPD---------------------------------
---------------------------------------------------------VTE
AALKVFALPGPADQK-TEIPIGPSSSYSH--EEKLKISPVILPDDQETELLTAPLSFYSK
REKPKISTVIGSDNQKTPLLTVLHNSYSQKVKPGIFLQHQLSDKHQSENILKIS-AVSEP
IDVN-----SGIPISLSSSYSHREKSNN--FYPQELPDKHLGKGALKVSTIPLPADQKSL
LPTAP-SSFSHREQPDIFCQQDFPDRHLTQDALMFSSGVGQADQITGLSTVTPGTYSYS-
---EKQKLV-SDH-VQMLIDNLDSS-N---SSVTSNS--MPLN-SQADG--RVIISKPES
SSFE----DVRS---EEIQDRSS--GSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLV
PFRDVSD-I--SFIQSKKVVCFKEPLTADEY--NGDLP-QRQPF---IEESPS-NKCIQK
DISTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-ARVTVD-ETCRQYRAA-KS
VMR-SEPEGY-SGTIGN-KIVIPMM-TIIKSDSS------SDASSCSWDSNSL-------
ESVSD-VLLNF-FPYSSPKTS-LTD--SRE-EGVSESDDGGGSSVDSLAAHVRNLLKCES
SLNHAKQILRNAEEEECRVRA--RAWNLKFNLAHE--CGYSISELNEDDRRKVEEIKAKL
FSHERTTDLSKGLQSPRGIGCKPEAVCSHIIIESHEKGCFRTLTA-EQPQLDSHPCV-FR
SADPSDMIRG-QRSPSSWRTRHIDLSK-SLDQCNPHFKVWNSLQLRSHSPFQNFAADDFR
ISQGLRMPFH---EKIDPWLSELV-----EPASVPL---EEMDCHSSSQMLPPEPMK--K
FTTSITFSSHRHSKCFSDS--SVLKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLEQR
TSSPSSFKIVSHSPDK--AVTILAESSRQSPKLSV--EHSQQEEKFLERSDFKSSDSEPS
TSTKCSNVKEVHFSDNH-TFISMSRPSSTL---------GVKEKNVTITPDLSSHIILEQ
RQLF--EQSKAPHADHHVRKHHSPPPQHQDYVAPNLPCRIFL--EKQELFEQSKAPHL--
-DHQMRENHSPFLQGQDYIASDLPSSIFLEQRQLFEQS-KAPDVD-HMGKYHSPLPQVQD
YVVEKNN-QHKFKSYISNMINVEAKFDNVISQSAPSQCTLVTSTSASTPPSNRKALSCFR
ITLYPKTPSKLDSGTLDKRFHTLDPASKTRMNSEFNSDLQT----ISSRSLEPTSKLLAS
KPIAQNQESLGFVGPKSSPDFQVVQSPLPDS-NDISQDLKSILFQNSQIVTSKQTQVNIS
DLEGYSSPE--GTPVSADRSSEGIK-APFSAFPGKLS-SDAVTQITTESPGKTMFSSEIF
INTKDRGLAISEPSTQ-KLGKGPVKFASSSSVQQITHPHGT-------------------
---DAQPSLLPYKPPGSTKMYYVPELRQIPPSL--DSKSDTTVESSHSGSNDAIAPDFPA
EVLGTRNDDLT--------------------------------------VPANIKHKEGI
YSKRVVPKASLL---VGRKTPQKDNADAQVQVSITDDENLSDKNQKKEIYTKKAVTKAAQ
PEE-ESLQKASKGSSDAAAAEHSARLQDIKLESLPDTKAI---KQKEEI-LNKRTFP--K
EAWKEDKESLQIDIAESRCHSEFENTTHSVFRSAKFYFHHPVHLPSDQDFCHESLGRS--
---VFMRHSLKDFFQHHPDKQREHTSLPSPRQNVEK-------TKTDYTRI-ESLSINVN
LEN-----DVMHTAKSR-ARDNPKSDKQLNDQ--KRDHKVTPEPTAQHTVSLNELWNRYQ
ERQRQQRPPQ-----FGDRKELSLVDRLDRLAKLLQNPITYSLRT-SESTQDDSRGERDV
KE-WSGRQQQQKSKLQKKKRYKSLEK-FHKNAGELKKSKMLS----------THQAGKSN
QIKIEQIKFDKYILRKQPDFHY-RNNTSSDSRP-SEE-SELLTDTATNLLSTTTSPVESD
ILTQTDREVTL-QERSSSISTIDTARLIQAFGHERVCLSPRQIKLYSSITDHQRRYLERR
SKKNKKALNMNHPQMTSEHTRRKHIQVADHVISSDSVSSSTSSFWSSSSTLCNMQNVQML
NKAVQ-AGNLEIVNGV-KKHTRDVGMTFPTPSSSEARIEEDSDM---------------T
S-WSEEKIEEKRLLTNYLGDKKLRKNKHSCCEGVSWFVPVENVKSEPKKENLP-KLHGPG
ICWFAPITNTKPWREPLREQNWQGQHVDGHR----PLAGPD----RERLRPFVRATLQES
LHLHRPDFISRSGERIKRLKLIVQERKLQNMLESEREALFNVSREWQGYRDPTHLLPKKG
FLDARKSRPIGKKEMIQRSKRI-YEQLPEVQRKREEEKRRLEYKSYRLRAQLFKKKVTNQ
LLGR--KVPWN---------------------------------------

MEPEDLPWPGELEEEEEEEEEEAEEKEEEAT----------------------AAAAANL
DVVVVEEVQEEAGREL---DSDS-HYGHQHLESTDDEEEEEDEEAKAWLQAHPGRILPL-
------------PSPPRH----RYSECERTSLEK-------IVPLTCHVW-QQILYQGNS
RTQISDTNVVCLDTTAQQGSGDDQKTESWHCLPQEMD-SSQTLDTSQTRFKVRREDTEVS
DFPSLEEGV-LTQSENQVKEPN--RGLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFASD
SLFHQSELSFAPLRGIPDKSEDTEWFSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTTVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDRYD-DLCSYMSWKTQKDTQQP
ETNLADKDQVSVATFSDITDENITAKRSDHFDAAYSYGQYWKEEASPKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDVITLDGLNE-----NAVV-CSER---ITEL-------------------------
------------------------------------------------------------
--------------------------QRKLTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDASKGG----------------------IAKVTDS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLTVSSLL----ET
TTGQHT-DTLNQRPLADTHLTEETLKVTAIPEPAYQKTATPTVLSSSHSHRGKPSIFYQQ
GLPDSHLTEEALKVLTVPGPTDQTTGLPTLTSTSYSHREKPGIFYQQELPESNLTEEPLK
VSAAPGPVEQKTGIPTVSSTSQSHGEDLLFFYRQTLPDGHLTNQALKVSAMSGPADQKTG
TATVLSTPHSHREKPGIFYQQE--FPDSHQTEETL-KVSVTPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYQHV-LADSHLPEEGLKVSA-VAGPADQKTGLPTVPSNAYSHRE
KLLIFYQ-QALLDSQLPEEV-LKNSAVS-----GPADGKTGTPTVTSTSSVSSSLGEKPG
AFYQQTLPNSHLTEEALKLSVVPVP-GDQKTGIPSAPSSFYSQREKPIIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSIFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPLGSFSHRENPSIFYQQELPDSHPTEKAVKVS-TGPGPADQKTEIPTV
QSSSYPQRE-KPGVLYPQVLSDSRLPEESLKVSAF-PGPADQTTDTPAVPSSFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGPADQKTGTPTVTSTSYSQYREKPSI-F
HQQALPGTHIPEEAQKVSAVTG-PGDQ-KTWIPRVLSTFYSQREKPDIFYQQTLPGSHIP
EEAQKVSAVPGPADQKTGTPTPTSTS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAY---------------------------------------------
-----------------EPVDQ-TT-G---TPAATSTSYSQHREKPRI-FYQ-QSLPS-S
HLTEEAR--KVS-AVPGP-VD-QK-TG-TPT-STSTFY-SH-TE-KP-GI-FY-QQV--L
PHS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VAYEPVDQTTG-TPT----ATSTSYSQHREKPSIFYQQSLPSSHLTEEAK
NV------SAVPGPADQKT-GIPTLPSTFYSHTEKPGI---FY-QQ-V-LP-HS-H----
LPEEALKVSAAPGP-VD-QTIGITTVT-SPSSSFGEKP-IVIYKQAFPDGHLPGQSLKVS
VAPG-PVDQTTGSPTVTSPSYSQHRAKPGGFYQPALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSCSLGEKPIIIYKQAFADGHLPEEALKVSIVSG--------PS----E
KKTEIPTGPL--GSSALGEKPITFYQQALLDSPLNKEVVKVSAAPGPADQKTETI-PVHS
TPYSNRGKPVIFYQQT-LSDSHVPEEALKVPPVPG-PDAQKTETPLVSSSLYSHREKPVV
FYQ-QALPDSQLTKEALKVSAVSQP-ADQKTGLSTVTSSFYSHTEKP--NTSYQKELPDS
HLTEKSLKVSDVPGPADQKSGLSTVTSTSYSHREKPIISYQQELP--RFTEAGLKILRVP
GPADQKTGI---NILSSNSYPQREQSVISYQEELPG--LTEVTLKAV---GVPGPAD-QK
TGIQIASSRSYSNREKPSIFHQQELPD--VTEEALNVFVVPGQGDQKA-EVPTVPLSYYS
HREKPSVISQ--------------------------------------QELP--DSHLTE
EALKISPVSIPAEQK-TGIPIGPSSSYSHSHKEKLKISTVHIPHDQKTEFPAATLSSYSQ
IEKPKISTVIAPNDQKTPSQTAFHSSYSQTVKPDILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRRVTEDVLKISTIPGPPSQKTV
LPTALPSSFSHREKPGIFYQKDSPDRRLTEDALKISSAFGQADQITELHTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DLGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NGDLL-QGQPF---TEESPS-SRCIQK
DIGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRRYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTADLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EQPQLDSHSCA-FR
SAEPSEMTRG-RQSPSSCRAKHVNLSA-SLDQNNSHLKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFH---EKMNPWLSELV-----EPAFVPP---KKVDFHSSSQMPSPEPVK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
TSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLPVDFEHSCQEEKPLEMSDFTGNHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVGRSSSRLGVKEKNVTVTPDLPSCIFLEQ
RELF--EQSKAPHTDDHVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFKQRKAPHV--
-DHQMRENHSPLLQGQDSIASDLPSPISLEQC----QS-KVPGIDDQMSKHHFPLPQGQD
CVMEKNN-QHKPKSHIS-SINVEAKFNNVVSQSAPNHCTLATS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRCHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVVQDQESLGFLGPKSSLDFQVIQPSLPDSN-TITQDLKTIPSQNSQIVTSRQTQVNIS
DFEGHSNPE--GTPVSADRLPEKIK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEITEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTIESSHSGSNDAVAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLWNENADASVQVLITGDENLSDKKQK-EIHSTRAVTEAAE
AKEKESLQKDTADSGDAAAAVHSAQVEDPEIKNSPDTKAI---TQKEEI-HRKRTVP--E
EAWTSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGRS--
---VFMRHSWKDFFQHHPDKHREHICLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVTDTTKSQ-ARDYPKYSGQINDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQKRQPE-----WGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHNDSRGERDV
KE-WRGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKTKVLS----------HHRAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSSTTSTVESD
ILTQTDREMAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLMTSEHTRRRRIQVANHVISSDSISSSASSFLSSNSTFCNKQNAHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPTSSEAKLEEDSDV---------------T
S-WSEEKREEKLLFTSYPGDRKLKKNKKNSHEGVSWFVPVENVESGSKKENVP-KTWGPG
VSWFEPITKTKPWREPLREQNWQGQHLDGRG----SLAGPGREDGRDPLKPFVRATLQES
LQFHRPDFISSSGERIKRLKLIVQERKLQSMLQSERDALFNIDRERQGHQNRMHPLPKRV
FLAVQKNKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEEEEEEKEEEATAAAA------------E-----AAAAATNLD
DVVVVEEVQEEAGREL---DSDS-HYGHQHLESTDDE---EDEEAKAWLQAHPGRILPL-
------------PSPPRH----RYSEGERTSLEK-------IVPLTCHVW-QQILYQGNS
RTQISDTNVVCLETTAQQGSGDDQKTESWHCLPQEMD-PSQTLDTSQTRFNVRREDTEVS
DFPSLEEGV-LTQSENQVKEPN--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFASD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTTVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDSYD-DLCSYMSWKTRKDTQQP
ETNLADKDQVSVTSLSDITDENIATERSDHFDAAYSYGQYWKQEASPKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDIITLDGLNE-----NAVV-CGER---ITEL-------------------------
------------------------------------------------------------
--------------------------QRKLTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDASKGG----------------------IVKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSFEDLSQLTVSSPL----ET
TTGQHT-STVNQRPLADTHLTEETLKVTAIPEPAYQKTATPTVLSSSHSHRGKPSIFCQQ
GLPDSHLTEEALKVLAAPGPTDQTTGIPTLTSTSYSHREKPGISYQQELPESNLTEEPLK
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQTLPDGHLTDQALKVSAMSGPADQKTG
TATVLSTPHSHREKPGIFYQQE--FPDSHQTEETL-KVSFTPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYPQV-LADSHLPEEGLSVSA-VAGPADQKTGLPTVPSNAYSHRE
KLRIFYE-QALLDSQLPEEV-LKNSAVS-----GPADRKTRTPTVTSTSSVSSSLGEKPG
AFYQQTLPNSHLTEEALKVSVVPGP-GDQKTGIPSAPSSFYSHREKPVIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSIFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPSGSFSHREKPSIFYQQELPDSHPTEKAVKVS-TGPGPADQKTEIPTI
QSSSYPQRE-KPSVFYPQVLSDSRLPEESLKVSAF-PGPADQTTDTPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGPADQRTGTPTVTSTSYSQYREKPSI-F
HQQALPGTHIPEEAQKVSAVTG-LGDQ-KTWIPGVLSTFYSQREKPGIFYQQTLPGSHIP
EEAQKGSTVPGPADQKTGTPTPTSTS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAY---------------------------------------------
-----------------EPVDQ-TT-G---TPTATSTSYSQHREKPSI-FYQ-QSLPS-S
HLTEEAR--KVS-VVPGP-AD-QK-TG-IPS-LPSTFY-SH-TE-KP-GV-FY-QQI--L
PHSHPTEEGLNISVAYEPVDQTT-------------------------------------
------------------------------------------------------------
--------------------G-TPT----VTSTSYSQHREKPSIFYQQSLPSSHLTEEAK
NV------SAVPGPADQKT-GTPTLPSTFYSHTEKPGV---FY-QQ-V-LP-HS-H----
LPEEALKVSVAPGP-VD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPDGHLPEESLKVS
VAPG-PVDQTTGSPTVTSPSYSQHRAKPGSFYQPALLGSQIPEEALRVSS-APGPADQTT
GVPTI----TSTSYSLGEKPIIIYKQAFADGHLPEEALKVSIVSG--------PT----E
RKTEIPTGPL--GSSALGEKPLPFYQQALLDSPLNKEVVKVSAAPGPVDQKTETI-PVYS
TPYSNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSHREKPVV
SYQ-QALPDSQLTKETLKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NTSYQQELPDG
HLTEKALKVSDVPGPADQKSGLSTVTSTSYSHREKPIISYQQELP--HFTEAGLKILRVP
GPADQKTGI---NVLSSNSYPQREQSVISYQQELPD--LTEVTLKAV---GVPGPAD-QK
TGIQIASSSSYSNREKPSIFHQQELPD--ITEETFNVFVVPGQGDQKA-EIPTVPLSYYS
HREKPSVISQ--------------------------------------QELP--DSHLTE
DALKVSPVSIPAEQK-TGIPIGPSSSYSHSLKEKLKISTVHIPDDQKTEFPAATLSSYSQ
TEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPDILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRHVTEDVLKISTIPGPPSQKTV
LPTALPSSFSHREKPDIFYRKDSPDRLLTEDDLKISSALGQADQITGLHTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DLGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NGDLL-QRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EQPQLDSHSCA-FR
SAEPSEMTRG-RQSPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFH---EKMNPWLSELV-----EPAFVPP---KKVDFHSSTQMPSPEPVK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
SSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLSVDFEHSCQEEKPLERSDFTGNHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVGRSSSRLGVKEKNVTVTPDLPSCIFLEQ
RELF--EQSKAPHTDDPVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQMRENHSPLPQGQDSIASDLPSPISLEQC----QS-KAPGVDDQMSKHHFPFPQGQD
CVVEKNN-QHKPKSHIS-SINVEAKFNNVVSQSAPNQCTLATS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKGCHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVVQDQESLGFLGPKSSLDFRVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSADRLPKKIK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEITEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAVAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLRNENADASVQVLITGDENVSDRKQK-EIHSTRAVTEAAQ
AKEKESLQKDTADSSAAAAAEHSAQVGDPEIKNSPDTKAI---TQKEEI-HRKRTVP--E
EAWTSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGRS--
---VFMRHSWKDFFQHHPDKQREHIYLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVTDTTKSQ-ARDYPEYSGQINDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERGV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKTKVLS----------HHGAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTATNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRRIQVANHVISSDSISSSASSFLSSNSTFCNKQNAHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPSSSEAKLEEDSDV---------------T
S-WSEEKREEKLLFTGYPRDRKLKKNKKNSHEGVSWFVPVENVESGSKKENVP-KTWGPG
VSWFEPITKTKPWREPLREQNWQGQHLDGRG----SLAGPGRVDGRDPLKPFVRATLQES
LQFHRPDFISSSGERIKRLKLIVQERKLQSMLQSERDVLFNIDRERQGHQNRMRPVPKRV
FLAVQKSKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEEE-EK-EEEATAAA-------------A-----EAAAAANLD
DVVVVEEVQEEAGREL---DSDS-HYGHQHLESTDDGEDEEDEEAKAWLQAHPGRILPL-
------------PSPPRH----RYSEGERTSLEK-------IVPLTCHVW-QQILYQGNS
RTQISDTNVVCLETTAQQGSGDDQKTESWHCLPQEMD-PSQTLDTSQTRFNVRREDTEVS
DFPSLEEGV-LTQSENQVKEPN--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFASD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTTVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDSYD-DLCSYMSWKTRKDTQQP
ETNLADKDQVSVTSLSDITDENIATERNDHFDAAYSYGQYWKQEASPKQTET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDIITLDGLNE-----NAVV-CSER---ITEL-------------------------
------------------------------------------------------------
--------------------------QRKLTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDASKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLTVSSPL----ET
TTGQHT-STLNQRPLADTHLTEETLKVTAIPEPAYQKTATPTVLSSSHSHRGKPSILYQQ
GLPDSHLTEEALKVLAAPGPTDETTGIPTLTSTSYSHREKPGIFYQQELPESNLTEEPLK
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQTLPDGHLTDQALKVSAMSGPADQKTG
TATVLSTPYSHREKPGIFYQQE--FPDSHQTEETL-KVSFTPGLADQKTEI------PAV
QSSS-YSQREKPS-ILSSQV-LADSRLPEEGLNVSA-VAGPADQKTGLPTVPSNAYSHRE
KLRIFYQ-QALLDSQLPEEV-LKNSAVS-----GPADRKTGTPTVTSTSSVSSSLGEKPG
AFYQQTLPNSHLTEEALKVSVVPGP-GDQKTGIPSAPSSFYSHREKPVIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHNEKSSIFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPSGSFSHREKPSIFYQQELPDSHPTEKAVKVS-TGPGPADQKTEIPTI
QSSSYPQRE-KPSVFYPQVLSDSRLPEESLKVSAF-PGPADQTTDTPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGPADQRTGTPTVTSTSYSQYREKPSI-F
HQQALPGTHIPEEAQKVSAVTG-LGDQ-KTWIPGVLSTFYSQREKPGIFYQQTLPGSHIP
EEAQKGSTVPGPADQKTGTPTPTSTS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NR
-PTE-EAL-KISVAY---------------------------------------------
-----------------EPVDQ-TT-G---TPTATSTSYSQHREKPSI-FYQ-QSLPS-S
HLTEEAR--KVS-VVPGP-AD-QK-TG-IPT-LPSTFY-SY-TE-KP-GV-FY-QQV--L
PDNHPTEEALKISVAYEPVDQTTGTPTA--------------------------------
------------------------------------------------------------
------------------------------TSTSYSQHREKPSIFYQQSLPSSHLTEEAK
NV------SAVPGPADQKT-GTPTLPSTFYSHTEKPGV---FY-QQ-V-LP-HS-H----
LPEEALKVSVAPGP-VD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPDGHLPEESLKVS
VAPG-PVDQTTGSPTVTSPSYSQHRAKPGSFYQPALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSYSLGEKPIIIYKQAFADGHLPEEALKVSIVSG--------PT----E
RKTEIPTGPL--GSSALGEKPLTFYQQALLDSPLNKEVVKVSAAPGPVDQKTETI-PVYS
TPYSNRGKAFIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSHREKPVV
FYQ-QALPDSQLTKETLKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NTSYQQELPDG
HLTEKALKVSDVPGPADQKSGLSTVTSTSYSHREKPIISYQQELP--RFTEAGLKILRVP
GPADQKTGI---NVLSSNSYPQREQSVISYQQELPD--LTEVTLKAV---GVPGPAD-QK
TGIQIASSSSYSNREKPSIFHQQELPD--ITEETFNVFVVPGQGDQKA-EIPTVPLSYYS
HREKPSVISQ--------------------------------------QELP--DSHLTE
EALKVSPVSIPAEQK-TGIPIGPSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQ
TEKPKISAVIGPNDQKTPSQTAFHSSYSQTVKPDILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRHVTEDVLKISTIPGPPSQKTV
LPTALPSSFSHREKPDIFYQKDSPDRRLTEDALKISSALGQADQITGLHTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DLGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NGDLL-QRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EQPQLDSHSCA-FR
SAEPSEMTRG-RQSPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFH---EKMNPWLSELV-----EPAFVPP---KKVDFHSSTQMPSPEPVK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
SSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLSVDFEHSCQEEKPLERSDFTGNHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVGRSSSRLGVKEKNVTVTPDLPSCIFLEQ
RELF--EQSKAPHTDDPVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQMRENHSPLPQGQDSIASDLPSPISLEQC----QS-KAPGVDDQMSKHHFPFPQGQD
CVVEKNN-QHKPKTHIS-SINVEAKFNNVVSQSAPNQCTLATS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRCHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVVQDQESLGFLGPKSSLDFRVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSADRLPKKIK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEITEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAVAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLRNENADASVQVLITGDENLSDKKQK-EIHSTRAVTEAAQ
AKEKESLQKDTADSSAAAAAEHSAQVGDPEIKNSPDTKAI---TQKEEI-HRKRTVP--E
EAWTSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGRS--
---VFMRHSWKDFFQHHPDKQREHICLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----GVTDTTKSQ-ARDYPEYSGQINDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERDV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKTKVLS----------HHGAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTATNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRRIQVANHVISSDSISSSASSFLSSNSTFCNKQNAHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPSSSEAKLEEDSDV---------------T
S-WSEEKHEEKLLFTSYPGDRKLKKNKKNSHEGVSWFVPVENVESGSKKENVP-KTWGPG
VSWFEPITKTKPWREPLREQNWQGQHLDGRG----SLAGPGREDGRDPLKPFVRATLQES
LQFHRPDFISSSGERIKRLKLIVQERKLQSMLQSERDVLFNIDRERQGHQNRMRPLPKRV
FLAVQKSKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPSPGELEEEEDKEEEEEAEVEKQAAEE------------------PR----DS-
--EETVNVEEEAGPES---DSDF-QDEFQELESTD---EEEDDEAKAWLQAYPGRAFPL-
------------PPPPRHL----YAA-ERPASPEVSGTRG---------------AAGRS
RRGVTSR--------SLPLTVPDGRTESWHCLLQERD-SFQTVDISQTRIIARAEVTEVT
DFPSLEEDK-LTQ-SGQVKEPN--SDLLCSSLLVIQDDFASPALPLLTCLTQDQ-EFGPD
SLFHQSELDFAPLRGIPDKSEDSEWFSRPSEVSEALFQATSEASSDLVNSCFSISQHPL-
TEGPQGKAE---------------------------------------------------
------------------------------------------------------------
-----S------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----DIITLDGDTEYSSLDENAAMCSER---VTESQ------------------------
-----------RQL----------------------------------------------
------------------------------------------------------------
--------------------------------------------------KSSI------
------IG--------------------D--SDIETHSCLSIEDLPNLDVSFPK----EN
IVGLHT-DNVNQKALTDSHLTKERLKVSNITEPSDQNTGTSTTIFTPYSQRKKSNILYQE
GLPDDNKIDQARTVSIVSGPTDQKSDVPILTSASYSQREKPDISYWQHLSGSHLP-----
------------------------------------------EEVLKISEYSDPEAQKTR
AQ--------RASRPSVHYSQI--LPGGPLPQETL-KTLEDYEPVDQKTVA------PTA
STAS-YSQRQRPS-VHFSQI-LPGGPLPQETLKALD-DYEPVDQKTVAPTASTASYSQKQ
RASAYSS-QALSDGALPEET----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------LKVS----------------
------------------------------------------------------------
-------------------------------DEPIDHKTGTPEA--------PSRPSI-Y
YQQALPGGPLPEKALKISYEP---IDQ-KTETQRMSSVSH--------------------
------------------------------------PQ-KR-PT-IS-SQ-DAL-LG-GA
-IPQ-EPW-EV-------------------------------------------------
--------------------------------------------------------S---
--------------DNYE-VE-LN-TG-IPT-VSTALY-SQ-RQ-RP-TV-YY-QPA-V-
PSG-------------------------------------------------LPEE-A-L
I-VSKD--YGPV-DQ-K-TA-TSR-TS-SASFS---------------------------
------------------------------------------------------------
-------------------------------QRQRP-G-V-YY-PQ-A-LS-DG-P----
LLEEALKVLGDSEP-VD-QKTRIPTPS-----SQNQRPSGILYQEALK----------V-
-SDE-PLDQEPGTPISYSESS-SQRQRPGVYLQQPLPHAYVSSS----------------
------------------------------------------------------------
----------------QRQIPNTHYQQAFPGSHLFEESLKAST---------GTS-ATSS
SSYPSGKESTTFYHQA-LPSSHLPEESPKVSTSPL-SADQKTGTP---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----TISSHSYPFVEKSIIFYQNDFPNSPLTTE---------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------TLNVEDILKIS-TVPEP
TDTS-----TGIPVLLSGSYSPREEYNS--FCPQELPDRHLTEGVLKVTIIPEPADKKTV
LVTALPSSFSHRGKRSISYQNDLTNRHLTEDALKVSSGLGQTDQIAGSPTVSPGAYSHG-
---DKHKLV-SEH-VQRLIDDLNSP-D---SYVSSNS--MPLNSQVDDA---DVINKPES
SVLG----DAGC---EEIQDTDH--SSKT-LKEIRSLL-ME-AENIALKRCNFPA--TLV
PFRDVND-V--PCVQSNKVVCFKEPSTSDVS---HDI-HQREPI---TDESPR-VDCIQK
DIGTQ--TNLKCQQGI-ENWEFFSSTTI--RSPLPEAGSM-ARTTLD-ETFRHYQAA-KS
VMR-SEPEGC-CSTIGN-KIIIPMM-TIIKSDSS-SDV---SDGCCSWDSNLP----ETL
ESVSD-VLLNF-FPHTPFKTS-IAD--SRDEEGLSESEDGCG-SVDSLATHVKHLLQCES
SLNHARQILKNAEEEECRVRA--RAWNMKFNLGHE--CGYSISELNEDDRRKVEEIKAKL
FGHGRATHVSEGLQSPWGIGCKPEAVCSHIIIESHEKGCFRTLNV-EQPQLDSHSCA-FK
SAGLSEVIQG-RQSPSSWRAGH-NLSK-SLDQNNHHFKVGNSLQLQSHSPFQQLTPDDFK
VSKDVEMPPFHANTNTDSWLSELA-----EPTCVPP---KGMDFPSTSQTPPPEPMK--Q
FTTSITFSSHRHSKCISDT--SVFKVGVTEG-SQYTGTSVGIFNSHVTEEQNSPRDLKKK
TFSPSSLKRHSHIPGK--EVAILVH-SRQNSKLPAGFEHSHQEEKLLERSNLKGNHSEHI
TSTNYSNSKGVQFSDNH-TLISMGKPSSTL---------EVKEKNVIITPDLPSCIFLEQ
RELF--EKSQALYTDHHMRKHHSPP-------CPDIPSCIFL--GQQQLIEQSKAPHL--
-DHEMRESHSFFSQSQENIILDLPSPIFLEER----QC-RSPDVDDHMTKQHVPLSQGQD
CVVEK-I-EYTTKSHICKGINAETEFSNVVSQSPPNHCTLVTS--ECTPPSNRKALSCVR
ITLCPKTPSKLDSGILNERFHSLDPASKTRINSELNSDLQT----ISSRSLEPASKLLTS
KPIAQNTESLDFLGPKSLPDLQVIRSPLPDS-KTITKDLKTIPTQDSQIVTSKQTQVNIS
DLEGYSKPE--GTSVSADGSPGQSN-IPFSASSGKLS-SDAVTQITTESPEKTMFLSEIF
INTDDNGHEGVDLSTQ-KT----HKVASSPSVQQVTTGSGP-------------------
---DAQPVLLPYKPSGSSKMYYVPQLQAVPSVP--DSKSDTTIESSHSGSNDAIAPNFPA
QVLGTRNDDLP--------------------------------------ATVNIKHKEGI
YSKRAVTKGPLS---MRKTLSQKDDAVQ--------------------------------
--------LE-----SSSSGAVAVQVQDRMTESLPGTKTM---TQKEEI-HNKKTIP--K
---------------ESECHSEFENTTHSVFRSAKFYFHRPVHPPNDQDFCHESLGRS--
---VFMRHSWKDFFHHHSDTHREHICLSPPYPLVDK-------TMVDYTRI-KSLSIDVN
VEDN----KMMHTKSQ---ARDPKNKRQINDS--KRDQKVTPEVTTQHTVSLNELWSKYQ
ERQKQQKPPD-----VCDRKELSLVERLDRLAKLLQNPITHSLQA-SE--RDNSRGRQNV
KG-WSYGKQQ-KSKLQ--KQCKSLER-G--HEGDFRKGKVLS-----------HQPGRSN
QIKIEQIKFDKYILSKQPNFNY-ISNTTSDSRP-SEE-SDLLTDSPTYVLSSTTSPVDSD
ILTQTDKDVTL-HERSSSISTIDTARLIHAFGHERLCLSPRRIKLYSSITNQQKRYLEKR
CKHNKKSLSIGHPQMTSEHTKRRHIQVANSMISSDCV-SSSSSVLSLNSALYNEQNVHML
NKGVQ-AGNLEIVTGA-KKHTRDVGVTFPTPSSSEARLEEDSDM---------------T
S-WSEEIVEEKMFLANNPGEKKLRKNK-NSCEGVSWFVPVGNMKSGSQKENLP-KSYGPG
VSWFEPVTKTKPWREPLREQNLQGRHMDCQE----SLGGPGGDDGQGPLKPFVRATLQEA
LQLHRPDFISRSGERIKRLKLIVKERKLQNMFQCERNALFNA----------PHPL SRRS
MSSC-------------PFP EI-YEQLPEVKKKREEEKRKSEYKTYRLRAQLYKTKVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEE---------EEA----------------------AAAAAANVD
DVVVVEEVEEEAGREL---DCDS-HYGPQHLESIDDEE---DEEAKAWLQAHPGRILPP-
------------PSPPQH----RYSEGEQTSLEK-------IVPLTCHVW-QQIVYQGNS
RTQISDTNVVCLETTAQRGSGDDQKTESWHCLPQEMD-SSQTLDTSQTRFNLRTEDTEVT
DFPSLEEGI-LTQSENQVKEPN--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFAPD
SLFHQSELSFASLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHPL-
IGSTAVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDRYD-DLCSYMSWKTRKDTQWP
ENNLADKDQVSVATSSDITDENIATKRSDHFDAACSYGQYWTQEDSSKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDVITLDGLNE-----NAVV-CSER---VAEL-------------------------
------------------------------------------------------------
--------------------------QRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDTSKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLAVSSLL----ET
TTGQHTADTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQ
GLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEETLE
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTG
TATVLSTPHSHREKP------E--FADRHQTEETLTKVSATPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYPQE-LADSHLPEEGLKVSA-VAGPADQKTGLPTVPSSAYSHRE
KLLVFYQ-QALLDSHLPEGA-LKVSAVS-----GPADRKTGTPTVTSTSSASSSLGEKPS
AFYQQTLPNSHLTEEALKVSVVPGP-GDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVYYQQELPDSDLPRESLKMSAIPGL
-TDQKTVPTPTVPSGSFSHREKPSIFYQQELPDSYATEKALKVS-TGPGPADQKTEIPAV
QSSSYPQREEKPSVLYPQVLSDSHLPEESLKVSAF-PGPADQMTDTPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGLADQKTGTPTVTSTSYSQHREKPSI-F
HQQALPGTHIPEEAQKVSAVTG-PGNQ-KTWIPRVLSTFYSQREKPGIFYQQTLPGSHIP
EEAQKVSPVLGPADQKTGTPTSTSAS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAS---------------------------------------------
-----------------EPVDQ-TT-G---TPAVTSTSYSQYREKPSI-FYQ-QSLPS-S
HLTEEAK--NVS-AVPGP-AD-QK-TV-IPI-LPSTFY-SH-TE-KS-GV-FY-QQV--L
PHS---------------------------------------------------------
------------------------------------------------------HPTEEA
LKIS------VASEPVDQTTG-TPT----VTSTSYSQHREKPSIFYQQSLPGSHLTEEAK
NV------SAVPGPADQKT-GIPTLPSTFYSHTEKPGS---FY-QQ-L-LP-HS-H----
LPEEALEVSVAPGP-VD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPDGHLPEESLKVS
VAPG-PVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSG--------PT----E
KKTDIPAGPL--GSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETL-PVHS
TTYSNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSYREKPIV
FYQ-QALPDSQLTQEALKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NISYQQELPDS
HLTEKALKVSYVPGPADQKTGVSTVTSTSYSHREKPIISYQRELP--HFTEAGLKILRVP
GPADQKTGI---NILLSNSYPQREHSVISYEQELPD--LTEVTLKAV---GVPGPAD-RK
TGIQIASSSSYSNREKASIFHQQELPD--VTEEALSVFVVPGQGDRKT-EIPTVPLSYYS
RREKPSVISQ--------------------------------------QVLP--DSHLTE
EALKVSPVSIPAEQK-TGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTQFPAATLSSYSQ
IEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPVSLSSSYFHREKSNI--FSPQELPGRHVTEDVLKVSTIPGPAGQKTV
LPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALEQADQITGLQTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDSLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DVGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENMALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTGVS--NGDLF-QRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCRRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VTR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EYPQLDSHPCA-FR
SAEPSEMTRG-RQNPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLQMPFH---EKMDPWLSELV-----EPAFVPP---KEVDFHSSSQMPSPEPMK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
TSSPSSFKMHSNSQDK--EVTILAEGRRQSQKLPVDFEHSFQEEKPLERSDFTGSHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVSRSSSRLGVKEKNVTITPDLPSCIFLEQ
RELF--EQSKAPRADDHVRKHHSPSPQHQDYVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQMRENHSPLPQGQDSISSDLPSPISLEQC----QS-KAPGVDDQMNKHHFPLPQGQD
CVVEKNN-QHKPKSHIS-NINVEAKFNTVVSQSAPNHCTLAAS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDERFHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTG
KPVAQDQESLGFLGPKSSLDFQVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPE--GTPVSADRLPEKMK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEIIEPGNQ-KLRKAPVKFVSSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAIAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLQNENADASVQVLITGDENLSDKKQQ-EIHSTRAVTEAAQ
AKEKESLQKDTADSSAAAAAEHSARVGDPEMKNLPDTKAI---TQKEEI-HRKKTVP--E
EAWPNNKESLQINIEESECHSEFENTTRSVFRSAKFYIHHPVHLPSDQDICHESLGKS--
---VFMRHSWKDFFQHHPDKHREHMCLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVMDTTKSQ-ARDYPEHNGQISDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERSV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKSKVLS----------HHRAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRHIQVANHVISSDSISSSASSFLSSNPTFCNKQNVHML
NKGIQ-AGNLEIVNGA-KKHTRDVGMTFPTPSSSEAKLEEDSDV---------------T
S-WSEEKREEKMLFTGYPEDRKLKKNKKNSHEGVSWFVPVENVESRSKKENVP-NTCGPG
ISWFEPITKTRPWREPLREQNCQGQHLDGRG----SLAGPGREAGRDLLKPFVRATLQES
LQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDALFNIDRERQGHQNRMCPLPKRV
FLAIQKNKPISKKEMIQRSKR---------------------------------------
--------------------------------------------------

MEPEDLPWPGELEEE-EEEGAE-----------------------------NL----DED
EVVMVEEMEEEERREP---EADF-NYESQRRESTD---DEDDEEAKAWLQAQPSAALPQA
SLP-RHR----------------FSESELTSPGK-------VLPLTCHLW-QQPLYQNDS
GTQISDTNVASLEKIAPWGSGDDQRTESWHCLPQEMD-SSCTLDTAQTGFNMREKGTEVT
DFTSLEEGI-STQSENQGKDPN--RDLLCSPLLVLQDSFASPDLPLLTCLTERQ-EFGPD
SLFHQSELDFAPLRGIPGKSEDTEWFSRPSEVSEALFQAASGVASDLVNSCFSISQHPL-
IGSTAVKSQHSLLTPEQGTREETVSSNTLDDQKTCEDSGNYD-AVYSYMSWETQEVMQEP
ATNLADKDQVSFSTASDISDEYINPKGSDSFDASYLYAQYENQGTLQ-QSEKYLVC----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------PSNTD
-------------------INESFSS----------------------------------
------------------------------------------------------------
--------------------VLPPFVPREPARDLEYHSSNLRMLRVSPDTASRTVRHLT-
GDTSKGG----------------------TAEIPQS------------TFKPGIT-----
----TFPE--------------------DS--DTVSPLSLSPEDFPQLAGRSPQ----VK
NIGGYT-DTLNQQTLVDSRLTEETLKISSIPGLADQKTRIAAVSSSSYSQREKPNIFYPQ
ALPDSHLTEEALKAGAVPGLGDQKTGLSTVPPSSYLLGEKHSIFYPQALPDSHQT-----
------------------------------------------EESLNVSVLPGLVDQKTG
KPIVPASSYSVGEEPGIFYHQV--LPDSQLPEEAL-KVLASPIPVDQKSGL------PTL
S-ST-YSYGEKPH-IFYQQT-LPDSHPTEQTLKVSA-APGLAEQKTGVPTITSPSYSHKE
---------------------------------------------------------KPS
IFYQPELPNRRLIQEAHQVSAAPGL-VEQKAGISIVPSTSYSQREKPNVVYQQELPDSHL
IQEVQQ-----------------------------------------------VSAVPGL
-AEQKT-GIPAIPSASYSHREKPSIVYQQELSDSQLIEQSQKVS-SVPGLAEQKTGIPTV
PSTSYSHREKSS-IFYQQELPDSHLIQEVQQVSTA-AGPLEQKTGIPTVPSTSYSH----
------------------------------------------------------------
------------------------------------------REKSSIFYQQELPDSHLI
QEVQQVSTAAGPLEQKTGIPTVPSTS-------YS-HR-EK-PH-IF-YQ-QEL-PE-SH
-VTE-QAQ-KVSSVP-GLAE-QKTG-ISTV-ASAS-YSHR-E------------------
--------------------------------------------KPSI-LYQ-QELPD-V
HVI-HKV-PEVS-SVPGL-AE-QK-AR-IPV-IPSTSY-SH-RE-KP-SI-LY-QQE-L-
PDS------------------------------------------------HLTEQ-V-Q
K-ASAA--PGPA-EQ-K-IG-IPI-IT-SASYLHREKP-VI-FYQ-QDL-PD-SHLTK-E
AQ-KVP-AVS-GL-AHQ-KSG-IPI-VPP-AF-Y-SH-GGKTGLFYQQELPDSHLSDQTQ
-K-I-S-AI--PGPVDQNT-GIQTAPSTSYSYREKP-I-T-FY-QQ-E-LP-GR-L----
LTEEVLKVSALPRT-TD-QNTGIITGS-SRSYLFGEKPSGLFYQQVLPDGSLTEEALKVS
PASR-PSDQKTGVLLLPASSY-SHREKPGIFYPQASPSSHLSEETLKDST-VLGPADQKA
GTS-E----PSGSYSHREESSIFYQQELPDSHITGEALKISGVSG--------TG----D
QKTGIPIVTS--PSYSQKEKPIVFYQQISPDSYLPEEALNVSNTPSRADQKTGIP-IVTS
PSFSYNEKPIIFYQQA-LPDSQLTVEALKVSDVPG-PSDQKTGIP---------------
----------------------------------TVPPSSYSYGEKP--VISYQQESPD-
-LTQVALKVFEVPGPADQEIGIPPVTSTSYSYGEKPIISYQQELPD--ANENALKGLGVP
RQADQTIG---VRIVPPSSYSHRESPIFSYQQE--LPDLTEEA-----------------
------------------------------------------------------------
------------------------------------------------------------
--LKVFALPGPPDQN-AEIPIGPSSSYSH--KEKLKI----LPDGQKTELPLTPSGSYSH
REKPKTSTVIGPADQKSPLLTGFPNSYPQRVKPSIFLQQQLADRHQSGDILKIS-PVAEP
TDVN-----SRIPIPLSSSHSHREKSNI--FYPQELPDKHLREDSLKVSTVPGPADKKTV
LPVVPPSSFSHREKPAILYHQDFPERHLTEDNLKFSSSLGQADQMNGLSTGPPGTYSHS-
---EKHKLV-SHH-VQRLTDNLDSS-H---TSVISNN--MPLN-SQADG--RVVINKPES
SGFE----DVGS---EEMRDTEN--SSKT-LKEIQTLL-ME-AENIALRRYNFPT--PLV
PFRDVSD-I--SFIQSKKMVCFKEPLTTDES--NGDLS-QRQPF---TEESPS-NKCIQK
DISTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAEGK-ARVAFD-ETLKKYRAA-RS
VMR-SEPEEY-SRTIGN-KIVIPMM-TIIKSDSS------SDASSCSWDSNSL-------
ESVSD-VLLNF-FPYSSPKTS-MTD--SREEEGVLESDDGGRSSVDSLAAHVKNLLKCES
SLNHAKQILKNAEEEESRVRA--RAWNLKYNMAHE--YGYSISELNEDDRRKVEEIKAKL
FGQGRTTDLSKDLQSPRGIGCKPEAVCSHIIIESHEKGCFRTLTA-ERPRLDSHPCV-FR
SAEPSEIVRG-QWSPSSWRTRHINLSK-SLDQNNSQFKVWNSLQLQSHSPFQNFISDDLE
ISKGLRMPFH---EKLDPWLSELV-----EPACMPP---EEMDCHSSSQMLPPEPMK--K
FTTSITFSSHRHSKCFSDS--SFLKVGVTEG-SQCSGASVGVVNSHFTEEQNPPRDLKQR
TSSPSSLKIISQSPDK--AVTILAENSSQSQKLSV--EHSYQEEKPLEKSDFKSSHPKPS
ASANDSNFKEVHFSDNH-TLISMGRPNSTV---------EVKEKNVTITAGLPSHIFLEQ
-EVF--EQSTAPHADQHVRKHHSPPPQHQDYVAPNLPCRIFL--EKRELFKQSKAPHV--
-D-QLRENHSPLPQSQDYIASDLPSSIFLEH--------KAPNVDHHLKKLHSPLSQSQD
SVVEKNN-EHKPRLHISDTIDVEAKFSDVVSPSAPNQCTVATS--ASSPPSNRKALSCIR
ITLSPKTPSKLDSGNLDKRLHSLDPATKTRMNSEFNSDLQT----ISSRSLEPTSKLLIS
KPVAQNQESLGFLGPKSSSDFQVVQSPLPDS-NVITQDLKTIPYQNSQIVTSRQTQVSSS
DLEEYSNPE--GTPVSADRSPEEIK-TLFSPSSGKLS-SDAVTQITTESPGKATFSSEIF
VNAGDHGREIPELSTQ-KLGNVPVKFASSSSVQQITVPHGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLTQIPSST--DSKSDTTIESSHSGSNDAIAPDFPA
QVLGTRDDDLA--------------------------------------DTVNIKHKEGI
YSKRAVTKASLS---MGKKPFQKDNA--DAQVLITGDEDLSDKNQEKEIYTKKAVTKIAY
SEEKESLQKDATGSSTAAASQHSTQLQ-DTKTDIKQ---------KEEI-HSKRKVT--K
EAWSEEKKSLQIDIAESKCHSEFENTTHSVFRSAKFYFHHPVHLPSDQDFCHESLGRS--
---VFMKHSWKDFFQHHPDKQREYTCLPSPCQHMEK-------TKTDYTRI-QSLSINVN
LENK----ELKHASKSQ-ARDFPKSDKQINDL--KRDPKATPELTTEHTVSLNELWNRYQ
ERQKQQK-PE-----FSAKKELSLVERLDRLAKLLQHPITHSLQP-SESTQDDSRGEQDV
KE-WGDKQQQQKNKLQKKKQYKSLEK-CHKNTGDLKKNKILS----------THQAGRSN
QIKIEQFKFDKYILRKQPGFHY-INNTSSDSRH-SED-SELLTDTATNILSTTTSPVESD
ILTQTDKEMTL-QERSSSISTIDTARLIHAFGHERVCLSPRRIKLYSSITDHQRRYLEKR
SKKNKKALNTGYPQITSEHTRRKHIQVTDHV-SSDSVSSSTSSFWSSNSTLCNKQNAHML
NKGVQ-AGNLEIVSGV-RKNTRDVGMTFPTPSSSEARMEEDSDV---------------T
S-WSEEKIEEKRLLTSYLVDKKLKKNKKSCCEGVSWFVPVENMKSGPKKENMP-KLHGPG
VSWFAPITNTKPWREPLREQNWQGRHMDSHS----SPAGPG----KEPLKPFVRATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLQNMLQSEREALFNAVQEWQGYQDPMHLLRKRG
FLAAQKKRPIGKKEMIQRSKRI-YEQLPEVQKKRDEEKRRSEYKSYRLRAQLYKKKVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEEE-EEKEEEATAAAA------------E-----AAAAATNLD
DVVVVEEVQEEAGREL---DSDS-HYGHQHLESTDDEEDEEDEEAKAWLQAHPGRILPL-
------------PSPPRH----RYSEGERTSLEK-------IVPLTCHVW-QQILYQGNS
RTQISDTNVVCLETTAQQGSGDDQKTESWHCLPQEMD-PSQTLDTSQTRFNVRREDTEVS
DFPSLEEGV-LTQSENQVKEPN--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFASD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTTVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDSYD-DLCSYMSWKTRKDTQQP
ETNLADKDQVSVTSLSDITDENIATERSDHFDAAYSYGQYWKQEASPKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
A-ESDIITLDGLNE-----NAVV-CSER---ITEL-------------------------
------------------------------------------------------------
--------------------------QRKLTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDASKGG----------------------IAKVTQS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLTVSSPL----ET
TTGQHT-STLNQRPLADTHLTEETLKVTAIPEPAYQKTATPTVLSSSHSHRGKHSIFYQQ
GLPDSHLTEEALKVLAAPGPTDQTTGIPTLTSTSYSHREKPGIFYQQELPESNLTEEPLK
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQTLPDGHLTDKALKVSAMSGPADQKTG
TATVLSTPHSHREKPGIFYQQE--FPDSHQTEETL-KVSFTPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYPQG-LADSHLPEEGLNVSA-VAGPADQKTGLPTVPSNAYSHRE
KLRIFYQ-QALLDSQLPEEV-LKNSAVS-----GPADRKTGTPTVTSTSSVSSSLGEKPG
AFYQQTLPNSHLTEEALKVSVVPGP-SDQKTGIPSAPSSFYSHREKPVIFSQQTLPDFLF
PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSIFYQQELPDSDLPRESLKMSAIPGL
-TDQKTVSTPTVPSGAFSHREKPSIFYQQELPDSHPTEKAVKVS-AGPGPADQKTEIPTI
QSSSYPQRE-KPSVFYPQVLSDSRLPEESLKVSAF-PGPADQTTDTPAVPSTFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGPADQRTGTPTVTSTSYSQYREKPSI-F
HQQALPGTHIPEETQKVSAVTG-LGDQ-KTWIPGVLSTFYSQREKPGIFYQQTLPGSHIP
EEAQKGSTVPGPADQKTGTPTPTSTS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAY---------------------------------------------
-----------------EPVDQ-TT-G---TPTATSTSYSQHQEKPSI-FYQ-QSLPS-S
HLTEEAR--KVS-VVPGP-AD-QK-TG-IPS-LPSTFY-SH-TE-KP-GV-FY-QQV--L
PHSHPTEEAPNISVAYEPVDQTA-------------------------------------
------------------------------------------------------------
--------------------G-TPT----ATSTSYSQHREKPSIFYQQSLPSSHLTEEAK
NV------SAVPGPADQKT-GTPTLPSTFYSHTEKPGV---FY-QQ-V-LP-HS-H----
LPEEALKVSVAPGP-VD-QTIGTPTVT-SPSSSFGEKP-IVIYKQAFPDGHLPEESLKVS
VAPG-PVDQTTGSPTVTSPSYSQHRAKPGSFYQPALLGSQIPEEALRVSS-APGPTDQTT
GVPTI----TSTSYSLGEKPIIIYKQAFADGHLPEEALKVSIVSG--------PT----E
RKTEIPTGPL--GSSALGEKPLTFYQQALLDSPLNKEVVKVSAAPGPVDQKTETI-PVYS
TPYSNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSSLYSHREKPVV
FYQ-QALPDSQLTKETLKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NTSYQQELPDG
HLTEKTLKVSDVPGPADQKSGLSTVTSTSYSHREKPIISYQQELP--RFTEAGLKILRVP
GPADQKTGV---NVLSSNSYPQREQSVISYQQGLPD--LTEVTLKAV---GVPGPAD-QK
TGIQIASSSSYSNREKPSIFHQQELPD--ITEETFNVFVVPGQGDQKA-EIPTVPLSYYS
HRQKPSVISQ--------------------------------------QELP--DSHLTE
DALKVSPVSIPAEQK-TGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQ
TEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPDILFQQQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGGHVTEDVLKISTIPGPPSQKTV
LPTALPSSFSHREKPDIFYQKDSPDRRLTEDALKISSALGQADQITGLHTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DLGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NGDLL-QRQPF---TEESPS-SRCIQK
DIGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRQYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIIIESHEKGCFRTLTS-EQPQLDSHSCA-FR
SAEPSEMTRG-RQSPSSCRAKHVNLSA-SLDQNNSHFKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFH---EKMNPWLSELV-----EPAFVPP---KKVDFHSSTQMPSPEPVK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
SSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLSVDFEHSCQEEKPLERSDFTGNHSEPS
TSANCSNFKEIQISDNH-TLVSMGRPSSTLGVGRSSSRLGVKEKNVTVTPDLPSCIFLEQ
RELF--EQSKAPHTDDPVRKHHSPSPQHQDSVAPDLPSCIFL--EQRELFEQCKAPYV--
-DHQMRENHSPLPQGQDSIASDLPSPISLEQC----QS-KAPGVDDQMSKHHFPFPQGQD
CVVEKNN-QHKPKSHIS-SINVEAKFNNVVSQSAPNQCTLATS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRCHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVVQDQESLGFLGPKSSLDFRVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQIQVNIS
DFEGHSNPD--GTPVSADRLPKKIK-TPLSAFSEKLS-SDAVTQITTESPEKTLFSSEIF
INAEDRGHEITEPGNQ-KLRKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSP--DSKSDTTVESSHSGSNDAVAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLRNENADASVQVLITGDENLSDKKQK-EIHSTRAVTEAAQ
AKEKESLQKDTADSSAAAAAEHSAQVGDPEIKNLPDTKAI---TQKEEI-HRKRTVP--E
EAWTSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGRS--
---VFMRHSWKDFFQHHPDKQREHICLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVTDTTKSQ-ARDYPEYSGQINDP--KRDQKVTPEQTTQHAVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERNV
KE-WSGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKTKVLS----------HHGAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTATNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIRLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRRIQVANHVISSDSVSSSASSFLSSNSTFCNKQNAHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPSSSEAKLEEDSDV---------------T
S-WSEEKREEKLLFTSYPGDRKLKKNKKNSHEGVSWFVPVENVESGSKKENVP-KTWGPG
VSWFEPITKTKPWREPLREQNWQGQHLDGRG----SLAGPGREDGRDPLKPFVRATLQES
LQFHRPDFISSSGERIKRLKLIVQERKLQSMLQSERDVLFNIDRERQGHQNRMRPLPKRV
FLAVQKSKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEDVEEEKEVEEK------TV---------EAVAVAEEP----AT-
SVEVMTEEEEEAGREL---DSDS-NYEVQPRESSDEE-DREDEEAKAWLQARPEVILLP-
-----------P-PLPRLLVHFRYTVQLYSL--------LDLVPLHDRSW-FSFYPLSLY
SL--HSSSLPSLQT-LHF-HFFIFKTESWQWLPQEIS-SSQTLDTSQTGINVKLKGNEMT
NFPSLEKGV-LIQSEDQVKEPS--RDLLCSPLLVIQDSFASPDLPLLTCLTQDQ-EFGPD
SLFQQSELDFAPLRGIPDKSEDSEWFSRPSEVSEALFQATLEVPSDFVSSCFSISQHSL-
TGNPTAGALRSFLSSEQEKNEDNVLSDTVDELKTPKDYYNYD-ALYSHMSWKTQKDTQQP
ENILADKDQVSVSTLSDISDENGVTKRSDSFVASSSNLQCWEPEALQ-RAEACLTNKDPV
YFP---------------------------------------------------------
---HDAAP-HHNKMSCSFLQCLLERRGKGV-PLTSDS---------HYFESDYLRVQAED
ELKQNTDSLKGYER-NEGLQQELCQRFKQKETKNNLIPSEV-----LRTCIRNFIVPDN-
-SVKVSEVLM-LSRGHDLSKMESSG---------AKSNLNETSKQLCFQEGRNQ------
----KTSSIFGEENVDA----------TENVAFEAVIASIEPSKKESTVSEIQTDISKSL
KDENHEREPENPDLSPLNCYNDES--SFFD-KLKHPNY-------QSAPGVFEPAASEPL
L----HVEDYDASFLFCYPNLKSP-PNAPQKMLIKPLSVIPEHKSSAS--LCEKPYMSQA
--------------------------VVKTQSSISTIDLAEKVGSSNII-YSMKLSASDS
LVSQDLKQQTFEEVA---------------------------------------------
-----------------------------------------------DSSDCNLEGLQGK
A-ESDVITLDDDTECCSLDEKAVVRSER---VAELQ------------------------
-----------R------------------------------------------------
-----EVGHSNLGINQSFSSILPPFISYEPTRESEHRSSNLRMLRFSPDTSLTVSVV---
------------------------------------------------------------
------SG---------------------S------------------------------
---------V--------------------------------------------------
---------------------DQKTETATVLSPSYSHKEKPNIFYQQELPGSYLTK----
-----------------------------------------DKETLKVSALPGAPDQKTG
IPTVSSTSYSSREEPGISYQQE--LPESHLTEETS-QVLGVSGPPDQKSRT------PHI
TSAS-YVQRKKPS-SLYQEG-LPDGHIPEQSLKVSA-VSESAKQKTGIQTITSPSYSQKD
KPDLFYQ-QPLPDSLLNEET-LK-------------------------------------
------------------------------------------------------------
---------------------------------------------------------VSV
-ADQKT-GITIV------------------------------------------------
SSTSYSHGEKSH------------------------------------------------
---------------------------------------------------------T-L
NLQALPESPLTATNLKESTL----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------RGFA-DQ-K-TG-IVT-VS-STSNS---------------------------
------------------------------------------------------------
--------------------------------LREN-S-I-LH-QQ-E-LV-QS-H----
LSEETLKVSSASGP-SD-PKNGILTTHSGGFYSQREKP-GISYQQTLSDIYTTKEPVKAS
AVYG-LADQKTGTPAVSSISH-SHREKPSVFYEQELPDNHPTEKSPEESV-VPGPADQKT
RIPAV----TSVLYSRREKPI-SYQPVLSGSHLPEDTLKVSAVSG--------PA----D
QIYHIPTLTS--APYSYKEKPSVFYQDKLLDGNL-ENAVKVSSAPGPVEQKTGTS-AVSS
ASYSQIDKPGIFYNHQ-------AEDILKVSSAPG-PDNQKGGIS---------------
----------------------------------TVTSTSYSHRKDP--GISSQKELPES
YIPRDSPKVS--ASPADQKTGTPTGSSSSYSLGEKPIIFYQPVLLSSHLPEEALKVLADS
AAAEQKTGT---PAVSSGSYVFGEKPPY-----QELPDLTEVASETVEVSANQKPNV-FK
IRVPLTPSSFYSHKEKPSVSLPQEFPD---------------------------------
---------------------------------KQKAGTPTGPFGSSSHGVK--PGGLTE
ESLKASAVPRLADQT-NRVPTLPSNFYSC--EEKPKISTVNMPDDKKIEPPTTTCSSYLQ
KDKPSISPVIGLNDQTAPLLTIFHSSYSQREKP----QQHLPDRDQSGDTLKIS-SVPEP
AVVN-----TGIPIPLSDSYLHREKSNT--FHLQELPDRNLTED----------------
----------------------------------VSTGLRQGDQITELPVVSSGTYLPD-
---EKHKLV-SEH-VQRLIHNLNSS-D---FSFRPNN--MFLNSQVDDG----VVTKPES
KRFE----DIGS---EEVQDTAN--SSKT-LKEIRTLL-ME-AENIALKRCNFSA--PLI
PFRDVND-I--SFIQSKKVVCFKEPSSIDVS---------NEPF---TEENPN-NRYIEK
DTGTQ--TSVKCQRGI-ENWEFISSTAI--RNPLQEVESK-ARVALD-ETFRQYEVA-KS
VLR-SEPEGY-SGTIGN-KIIIPMM-TFIKNDLS-SDASD-GNASCSWDSNLP----ESL
GSVSD-VLLNF-FPYTSSKAS-LTD--SREEEGVSESEDGGG-SVDSLAAHVRNLLQCES
SLNHAKQILRNAEEEEYRVRT--RAWNMKYNLADD--HGYSISELNEDDRRKVEEIKAEF
FGHRRTPDLSEGLQSLRGVGCTPEPVCGHIIIESHEKGCFSTLTA-EEPQLDSRSCV-FR
SAEPSEVIRG-RRCPSPWRARHINFSK-SLEQNNPHFRVWNSLQLQSHSQFHNS------
ISKDLRMPSR---EKTEPWLSELV-----EPACA--------DFHSSTQIPTPEPMR--Q
FTTSITFSSHRHSKCISDS--SVFKVGVTES-SQGTGASVGVFNSNVTEEQTPPRDFKQK
TSSPSSLKTFNHSPDK--DVTVALEGNRQREKSPVDFEHSHQEDKLLERSDFKVSPSEPS
SSANCSNFKEVQFSDNH-TLISMSRPNSTL---------EVKENNITITPDLPSLIFLEQ
RELF--EQSKVPLSDHHVRKHHSPF-------CPNVPSCIFL--EQRELFKQSKPPHT--
-DPEMRENHSSFSHCQDYIASDLPSSIFLEQH----QS-KALSVDDHMRKDHFSLSQGQD
CIAEK-N-KHTPKSHISN-INVEAKFNNLMSQLPPGHCTLTAS--ASAPSSNKKALSCVR
FTLCPKTPSKLDSGTLDKKFYPLDSASKTRMNSEFNSDLQT----VSSSLLEPASKLLTS
KSVAQNQEPLGFLRLKSPLDLQVVQSPLPDS-NSIVQDLKTVPSQNSQITTSRQIQVNIS
DLEGYSKPE--GTLVSADRSLEQSK-TQISAFSGKLS-SDAVTQITTESPEKTMFSSEIF
INAEDHGPD-----------KLPVRFASSSSVQQITSNRGT-------------------
---DAQPVLLPYKPSGSPQMYYVPQLQTVPPIL--DSKSDTTIESSHSGSNDAIAPDFPT
QVLGTRDDDLP--------------------------------------STVNIKHKEGI
YSKRAVTKTFQ-----------KD-KSAAVQVAITGGENLSDKNQKEDIFSRGVMTKTAW
PEEKESMQKVTAG----------TQVQVTKTESIPDTKAT---KQNEI--HIKGTIP--K
---------------ESECHSEFENTTHSVFRSAKFYFHHPVHLPSDQDTCHESLGKS--
---VFMRQSWKDFFQHHSDKHKEHTCLSPPYQNVDK-------TNTDYTRI-KSLSINVN
LGDK----KMIHTTKSQ-AIDHPKSTIQISDS--QKNYKITSELTTQHTLNLNELWNKYQ
ERQRQQKPPG-----IGDRTELSLVERLDRLAKLLQNPITHSLQA-SESMQDDSRRQQDI
KE-WNGKQQQPKRKLQK-KRYKSLEK-GHKDIGDLKKHKVLS----------GHQTGVPN
QIKIEQIKFDKYILQRQPCFNY-ISNTSSDSRP-SEE-SGLLTDTTTNILSTTT-SVDSD
ILTQTDREVAL-HERSSSISTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
CKHNKKAFNTGHPQMTSEHTRRRHIQVAHHI-SSDSV-SSASSLLSLNSTLCNEKNGHML
NKGIQ-AGNLEIVTGA-RKHTRDVGVTFPTPSSSEAILEEDSDV---------------T
S-LSEEKIEEKQLFTSYLEDKKLRKIKANSYEGVSWFVPVENVKSRSKKENMP-KIYGPA
VSWFEPITKTKPWRKPLREQNWQRQHVDSQGS----VA--DRDDGQGPPRPFVKATLQES
LQLHRPDFISRSGERIKRLKLIVQERKLQNMLQSERDVLFNT----------MRPLPRRV
FLAAQKKKPIGKKEMIQRSKRI-YEQLPEIQKKREEEKRRSEYKSYRLRAQLYKKKVTNQ
LLGR--KVPWD---------------------------------------

MEPEDLPWPGELEEEEEEEKEEEA---------------------------TAAAAANLD
NVVVVEEVQEEAGREL---DSDS-HYGHQHLESTDDEEDDEDEEAKAWLQAHPGRILPP-
------------PSPPRH----RYSECERTSLEK-------IVPLTCHVW-QQTLYQGNS
RTQISDTNVVCLETTAQQGSGDDQKTESWHCLPQEMD-SSQTLDTSQTRFNVRREDTEVS
DFPSLEEGV-LTQSENQVKEPS--RDLFCSPLLVIQDSFASPDLPLLTCLTQDQ-EFASD
SLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSCFSVSQHPL-
IGSTTVGSQCPFLPSEQGNNEETIS--SVDELKIPKDCDSYD-DLCSYMSWKTRKDTQQP
ETNLADKDQVSVATLSDVTDENITTKRSDHFDAAYSYGQYWKEEASPKQAET--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------YLTKGLQGK
T-ESDVITLDGLNE-----NAVV-CSER---ITEL-------------------------
------------------------------------------------------------
--------------------------QRKLTRESEYHSSDLRMLRMSPDTVPKAPKHLKA
GDASKGG----------------------IAKVTDS------------NLKSGI------
---TTTPVDS------------D----I------GSHLSLSLEDLSQLTVSSPL----ET
TTGQHT-GTLNQRPLADTHLTEETLKVTAIPEPAYQKTATPTVLSSSYSHRGKPSIFYQQ
GLPDSHLTEEALKVLTVPGPTDQTTGLPTLTSTSYSHREKPGIFYQQELPESNLTEEPLK
VSAAPGPVEQKTGIPTVSSTSHSHGEDLLFFYRQTLPDGHLTDQALKVSAMSGPADQKTG
TATVLSIPHSHREKPGIFYQQE--FPDSHQTEETL-KVSVTPGPADQKTEI------PAV
QSSS-YSQREKPS-ILYPHV-LADSHLPEEGLKVSA-VAGPADQKTGLPTVPSNAYSHRE
KLLIFYQ-QALLDSQLPEEV-LKNSAGPDIGTAVTSDGKTGTPTVTSTSSVSSSLGEKPG
AFYQQTLPNSHLTEEALKLSVVPGP-GDQKTGIPSAPSSFYSHRERPITFSQQTLPDFLF
PEEALKVSTISVLAAQKTGTPTVSSNSHSHSEKSSIFYQQELPDSDLPRESLKTSAIPGL
-TDQKTVPTPTVPSGSFSHRENPSILYQHELPDSHPTEKAVKVS-AGPGPADQKTEIPTV
QSSSYPQRE-KPSVLYPQVLSDSRLPEESLKVSAF-PGPADHTTDTPAVPSSFYSQR-EK
PGIFY------QQTLPESHLPKEA-LKISVAPGPADQKTGTPTVTSTSYSQYREKPSI-F
HQQALPGTHIPEEAQKVSAVIG-PGDQ-KTWIPRVLSTFYSQTEKPGIFYQQTLPGSHTP
EEAQKVSPVPEPADQKTGTPTPTSTS-------YS-HT-EK-PG-IF-YQ-QVL-PD-NH
-PTE-EAL-KISVAY---------------------------------------------
-----------------EPVDQ-TT-G---TPAATSTSYSQHREKPRI-FYQ-QSLPS-S
HLTEEAR--KVS-AVPGP-VD-QN-TG-TPT-STSTFY-SH-TE-KP-GV-FY-QQV--L
PHS---------------------------------------------------------
------------------------------------------------------HLTEEA
LKIS------VAYEPVDQTTG-TPT----ATSTSYSQHREKPSIFYQQSLPSSHLTEEAK
NV------SAVPGPADQKT-GIPTLPSTFYSHTEKPGI---FY-QQ-V-LP-HS-H----
LPEEALKVSVAPGP-VD-QTIGTTTIT-SPSSSFGEKP-IVIYKQAFPDGHLPGESLKVS
VAPG-PVDQTTGSPTVTSPSYSQHRAKPGGFYQPALLGSQIPEEALRVSS-APGPADQTT
GIPTI----TSTSYSLGEKPIIIYKQAFADGHLPEEALKVSIGSG--------PT----E
KKTEIPTGPL--GSSALGEKPITFYQQALLDSPLNKDVVKVTAAPGPADQKTETI-PVHS
TPYPNRGKPVIFYQQT-LSDSHLPEEALKVPPVPG-PDAQKTETPSVSSNLYSHREKPVV
FYQ-QALPDSQLTKEALKVSAVPQP-ADQKTGLSTVTSSFYSHTEKP--NTSYQQELPDS
HLTEKALKVSDVPGPADQKSGLSTVTSTSYSHREKPIISYQQEVP--RFTEAGLKILRVP
GPADQKTGI---NILSSNSYPQREQSVISYQQELPD--LTEVTLKAV---GVPGPAD-QK
TGIQIASSSSYSNREKPSIFHQQELPD--VTEEALNVFVVPGQGDQKA-EVPTVPLSYYS
HREKPSVISQ--------------------------------------QELP--DSHLTE
EALKVSPVSILAEQK-TGIPIGPSSSYSHSHKEKLKISTVHIPHDQKTEFPAATLSSYSQ
IEKPKISTVIAPNDQKTPSQTAFHSSYSQTVKPDILFQHQLPDRDQSKGILKIS-AVPEL
TDVN-----TGKPIPLSSSYFHREKSSI--FSPQELPGRRVTEDVLKTSTIPGPPSQKTV
LPTALPSSFSHREKLGIFYQKDSPDRRLTEDALKVSSAFGQADQITELHTVPSGTYSHG-
---ENHKLV-SEH-VQRLIDNLNSS-D---SSVSSNN--VLLN-SQADD--RVVINKPES
AGFR----DLGS---EEIQDAEN--SSKT-LKEIRTLL-ME-AENIALKRCNFPA--PLA
PFRDISD-I--SFIQSKKVVCFKEPSSTDVS--NGDLL-QRQPF---TEESPS-SRCIQK
DTGTQ--TNLKCQRGI-ENWEFISSTTV--RSPLQEAESK-VSMALE-ETLRRYQAA-KS
VMR-SEPEGC-SGTIGN-KIIIPMM-TVIKSDSS-SDASD-GNGSCSWDSNLP----ESL
ESVSD-VLLNF-FPYVSPKTS-ITD--SREEEGVSESEDGGGSSVDSLAAHVKNLLQCES
SLNHAKEILRNAEEEESRVRA--HAWNLKFNLAHD--CGYSISELNEDDRRKVEEIKAEL
FGHGRTTDLSKGLQSPRGMGCKPEAVCSHIVIESHEKGCFRTLTS-EQPQLDSHSCA-FR
SAEPSEMTRG-RQSPSSCRAKHVNLSA-SVDQNNSHLKVWNSLQLKSHSPFQNFIPDEFK
ISKGLRMPFR---EKMNPWLSELV-----EPAFVPP---KKVDFHSSSQMPSPEPVK--K
FTTSITFSSHRHSKCISNS--SVVKVGVTEG-SQCTGASVGVFNSHFTEEQNPPRDLKQK
TSSPSSFKMHSNSPDK--EVTILAEGRRQSQKLPVDFEHSCQEEKPLERSDFTGNHSEPS
TSANCSNFKEIQISDNH-TLISMGRPSSTLGVGRSSSRLGVKEKNVTVTPDLPSCIFLEQ
RELF--EQSKAPHTDDHVRKHHSPSPQHQDFVAPDLPSCIFL--EQRELFEQCKAPHV--
-DHQMRENHSPLPQGQDSIASDLPSPISLEQC----QS-KVPGVDDQMSKHHFPLPQGQD
CVVEKNN-QHKPKSHIS-SINVEAKFNNVVSQSAPNHCTLATS--ASTPPSNRKALSCVR
ITLCPKTSSKLDSGTLDKRCHSLDAASKARMNSEFNFDLHT----VSSRSLEPTSKLLTS
KPVVQDQESLGFLGPKSSLDFQVVQPSLPDSN-TITQDLKTIPSQNSQIVTSRQTQVNIS
DFEGHSNPE--GTPVSADRLPEKIK-TPLSAFSEKLS-SDAVTQITTQSPEKTLFSSEIF
INAEDRGHEITEPGNQ-KLCKAPVKFASSSSVQQVTFSRGT-------------------
---DGQPLLLPYKPSGSTKMYYVPQLRQIPPSL--DSKSDTTIESSHSGSNDAVAPDFPA
QVLGTRDDDLS--------------------------------------ATVNIKHKEGI
YSKRVVTKASLP---VGEKPLRNENA----------------------------------
------------DSGDAAAAEHSAQVEDPEIKNSPDTKAI---TQKEEI-HRKRTVP--E
EAWTSNKESLQINIEESECHSEFENTTHSVFRSAKFYIHHPVHLPSDQDICHESLGRS--
---VFMRHSWKDFFQHHPDKHREHICLPLPYQNMDK-------TKTDYTRI-KSLSINVN
LGNK----EVMDTTKSQ-ARDYPKYSGQITDP--KRDQKVTPEQTTQHTVSLNELWNKYR
ERQRQQRQPE-----LGDRKELSLVDRLDRLAKILQNPITHSLQV-SESTHDDSRGERDV
KE-RRGRQQQ-RNKLQKKKRFKSLEK-SHKNTGELKKTKVLS----------HHRAGRSN
QIKIEQIKFDKYILSKQPGFNY-ISNTSSDCRP-SEE-SELLTDTTTNILSSTTSTVESD
ILTQTDREVAL-HERSSSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKR
SKHSKKVLNTGHPLVTSEHTRRRRIQVANHVISSDSISSSASSFLSSNSTFCNKQNAHML
NKGIQ-AGNLEIVNGA-KKHTRDVGITFPTPTSSEAKLEEDSDV---------------T
S-WSEEKREEKLLFTSYPGDRKLKKNKKNSHEGVSWFVPVENVESGSKKENVP-KSWGPG
VSWFEPITKTKPWREPLREQNWQGQHLDGLG----SLAGPGREDGRDPLKPFVRATLQES
LQFHRPDFISSSGERIKRLKLIVQERKLQSMLQSERDVLFNVDRERQGHQNRMHPLPKRV
FLAVQKNKPISKKEMIQRSKRI-YEQLPEVQKKREEEKRKSEYKSYRLRAQLYKKRVTNQ
LLGR--KVPWD---------------------------------------

Query Results

"ENSGT00900000141032_1"

ENSGT00900000141032_1