Query Results 

------------------------------------------------------------
-------------------------------------------------------LHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTG
NLSRNSASSSLSPGSGSTDSDSSFPPTPTTE--RSVA--TSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGMAFLAIIKAIDPSLVDMKQALEDSARANLEKAFSIAHEALRIP
RLLDPEDIMVDPPDEQSIVTYVAQFLERFPELEVEDFMESDKEIPVESTFVRIKETPS--
EQESKILLVTENGECAYSVSHDTSHPPPAKVFVCDSP---ES-----VQGMCLSGSR---
VLSDSSSDFMHQIIDQVLQGSPGKT-GSTGEPPLESSILATRKDGRRSNSLPIKKTVHF-
-EADVYKDASCSKDPFYTQDLRFEGSPRTAQV------GQGPAADAAEDK-ELQHEVAKT
PEAAPNGVPRG-VPAAAGSL-----SSSQPPSPCDGAEESP-ASHREESHPPPPPAEDTL
-MASSLEVKVK-LLTVEAMDKDECFDSIPLKASKFSNNLVDFASTSRAVGEVPSPREETP
AED-EGFEDQDENFVGKRSAKSAHKKQESSECQVESSEHE-LPSD-----------A---
-------TLEETAERKPE--VYEKAKRKSTCRRRRSRGEGEEEEGEG-LQ--------GP
-GGELPSNP-TSSSVSLERLGSPGKDGVDFTPSPPLSKVSVIPHDLFYYPHYEVPLAAVL
EAYVEGTEDLKME-ETDL--GEQEG-GCS--------------------HPREEADASWS
SCSFSGPG-EGLPRASDLE-PAP---NKAATPASDPAPPDPR-ED---------------
--CQPRQTEE--SDPV-ESPQSQESP-SLESV-ANPLEAKVVEE-SISSKKKEKRKHVDH
VESSLFVAAGAVRSSDDLDD-DPGDR-RVPSRTSHSDSSIYLRPHTNRSLESDHFSYVHS
RNAADLDDRRHRILTRKAD-----------------------------------NSGEAA
APGTHSPHSDSLTQLVQ--------------------QPDLVY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAA-QEWDWFQREELI----GQ---ISD------IRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALTFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSYPPTPTAE--SNVA--IAMKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEESPRENLERAFQVAQETLHIP
RLLEPEDIMVDVPDEQSIVTYVAQFLERFPELEAEDFMDPDKEVPIESTFVRIRETPP--
EQESKVLLLMQNGERTYTVNHETSHPPPTKVFLCDRP---EG-------------MASSV
LS-DSSTEFVHQIIDQVLQEGLGT----SSEPAPESSNLCPRRNSQRPSFLPTKKTVHF-
-EDGAYKEPSGSQEPFYSPHFVFEGSPRPSRELL-QQGRRALLEAEAEERKLEE-AASPI
PGAGSGEVPGA-----HGPVS-P-TQPPPDSSSLNGTYEDLAGHLGEENPSLQPLGVNTV
-LASSMEIKVK-LQTAEPMGTEDYLEGVPSQARRFVSDSVDFASTSQGSGETSPGEKATG
----------------KEEAVEAASGNSAQEPQGGCDRHEHPTDS------------GQK
SPSHSSSPKETPVDRKPETPVYEKAKRKSPRHRSEDEE------DARGPPG---------
LGKELSSSS-LRASISLETVGSPSEEGLDFKSSPPLSKVSVIPHDLFYYPHYEVPLAAVL
EAYAEGTEDVNDK-----------DCLP-DMDPGEGN-----------------TEGSWS
SCSFSTLG-EGLPTASSQT-LPPTSHATAVTPASEAAAPALC-ED---------------
--QQPREAED----SE-SHQFQQEFP-DSENI-ANCLEEKVMQESSTSSKKKEKRKHVDR
VDTSSYTAPGIVQSSDDLED-DLGDC-RVPSRTSHSDSSIYIRRHTNRSLELDHISFVQL
RNAADLDDRRNRMLTR-----------------------------------KPSSSGEAE
SLGTQSLQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDIIRL---------------

--------------------MAG-HEWDWFQREELI----GQ---ISD------IRVQNL
QVERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCKPPLEVKDLFIDIQDGKILMALLEVLSGQSLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLNRNSSSSSLSSGTPGPESDSSLPMTPKGE--NIVA--LTVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RTLLNWVQRRT
RKYGVAVQDFAGSWRSGLAFLAIIKAIDPSLVDIKQALETPARENLEKAFSLAHDKLHIP
RLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPDKEIPIESTFVRIKETPT--
EQESKILLLPEKGEHTYTVNCETSQPPPPIIFVSDAS---EV-GKELIPSECPSESSGHR
RP-DSPKNQLPHIAEQAFPGGLNKP-SDINESVSEPSILLPKKAGHRPDSLPIKKTVHF-
-ESDISRDASCSKDISFKRDSGKINEP------L-KQDASVSSSGISNKTKAKE-GRMKT
LGSALNKILDD-YPLTHKKNT-V-------------FSPSE-VLPGTTERENVETNKEDI
-SPHSLEVKGQ-KLIQETLNEAAKFEEMTLKTLKQSTEMKGLTEVSQILHDKNSSPGEKN
AC--DKVSEANVEQLTKKASKCRRKMKDLTTDKSDTDMHSSNGNTVDPSDHLSLASPD--
--------------------NCEKAKQKSV-----HFD----QEENTPPEDHLESQDDLD
DEISTP--L--SSSISLETLGSQSEDSLDFKLSPPSSKVSVIPHDLFYYPHYDVPLSAVL
EAYVEASHGS----QNE-------EMVP-EKSTEDAQELD------------TKGKDPQK
YCKSKPNY-SVTE---------VR---SDVQQMDSPGHPSET-QPSSET-----VEANVL
VEHEEKEPSY--SGSV-NSSQGEEPN-NPVQLKSRNLNEKLPEE-ASSNKKTEEWNHGDQ
SDSSLFVAAKAAHFSEDLEE-EIIDR-KVISRTSHSDSSLYVRRQGNRSSDMDHVSHGRL
RPS-DMEERRTRLLIRYHTKKFTELILQVCGFKVDMKRR---CKSARKSMKKVSNYGEAM
-LQDHGTHSDSFVHFAQ--------------------QQDLVY----FILFLWLLVYCLL
LFPQLDIKKL---------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSVA--VAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLSWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFRIAHDSLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELDPEDFVNPDKEAPIESTFVRIKESPS--
EQESRVLLLSQNGEQPYTVSHETSHPPPDKVFVCDQL---ES-----PTGFSLGSAPSHK
LP-DSPTDFMHQIIDQVFQASMGNTE-STTEPTPESSILSTRKDGRRSNSLPVKKSVHF-
-ETDLHKDASCSKDPFYSSEFRFEGSPKATKELS-KQDGHASLAEVSKEK-KPEQEARLV
LEAASDKAPEDTIVDTDAMSQ-D-AQLPQDSSFCNGNVENP-ASLGEKGPSPPSPRDNTI
-LANSVELKVP-LLTVEPMDKDDYFECIPLKASKFNRDLVDFASTSQAFVEDPSSHKKTP
GEE--EGSENYTEKPGKRKSKSPHAETESTESRLEPIKLETPPKD-----------PEQE
DQGHTLPPE-TAADKKPE--VYEKAKRKSTRH-----HSEEEGEAEGGLS--------AV
-GGEMPSNP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKSE-DADL--EHPDGSYLQDSREEEEE----------EDEEEEEAHSSHS
SCNFSLPVDNSYPRVNDHV-SHVDGSSEGPTSASEPGSPPSH-ED---------------
--HQPMETKE--NGPV-ESQQSQEPP-TPELS-TKPLEEKLTEV-PTSSKKKEKRKHMDH
VESSLFIAPGTVRSSDDLEE-NPCEH-KVPSRNSHSDSSIYIRRHTNRSLELDHFSYVQL
RNAADVDDRRNRLLNR----------------------------------TGTNSSGEAV
PLGSQSPPNDSLTQFVQ--------------------QPDVIY----FILFLWLLVYCLL
LFPQLDVSRL---------------

------------------------------------------------------------
--EREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWMNL-HLEKCDPPLEVKDLFLDIQDGKILMALLEVLSGRSLLHEYK
SSSHRIFRLNNIAKALRFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTE--KNVA--ITVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIKTLLAWVQRKT
RKYGVAVQDFADSWRSGMAFLP-IKAIDPSLVDMKQALEDSPRENLEKAFSVAHEVLHIP
RLLDPEDIMVDSPDEQSIVTYVAQFLERFPELEVEDFLESEKEMPIESTFVRIKETPL--
EQESKILXXXXXXXXXXXXXXXXXXXXXXXXXVCDSP---ES-----VKGVCVDR--SRS
LA-DSSSDFVHRIIDQVFQGSPGKT-SSPGEPPLESSILATRKDGRRSNSLPIKKTVHF-
-EVDLYKDASCSKTLSL----RFEGTLQAAKGSA-------------TEDKQQV---ANA
PEVASNGILED-ASVATGFLS-S-SQPSQSSSPCNDVMESP-ASPGKESHSPVPPTEDSP
-MASPLQIQAEQQLAVEAMDGDDSFDSVPLKTSKFNRDLVEFASTSQTFGEGSSPPEKTP
AG--DEGAEMQEDKTGKRRAKSACKRKEPSECPEEASDHGPPGEA------------GPE
APSSSLAPEEAV-VHKPE--VYEKAKRKSICHRRHSGE----EEEEEEKEA----EGQQG
ADAELPSNP-ASSSVSLETLGTPSKERVDFAPSPPLSKVSVIPHDLFYYPHYEVPLAAVL
EAYAEGAEDLKME-EMDL--EEPEEAHLHDPEPR------------------EQAEGSPN
RCNFSGPG-VSSLG------PGPG---RGASPALDPAPPDPH-ED---------------
--HQPRATEK--SDPV-QSQQCQESP-NLEPV-ASPSEAKAVGE-SVSSKKKEKRKHVDH
AESSLSVVAGTVQSSDDLDE-ELRDC-RVPSRTSHSDSSIYIRRHTNRSLESDHFSYVHS
RNAADLDDRRNRIL-----------------------------------SRKANSSGEAA
VLGAQSPHDDSLTQLVQ--------------------QPDLVY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
--EREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKKTFTRWINL-HLEKCNPPLEVKDLFIDIQDGKILMALLEVLSGQNLLHEYK
SSSHRIFRLNNIAKALKFLKDSSVKLVSIDAAEIADGNPSLILGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTE--RNAA--ISVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIRTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAIIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDALHIP
RLLEPEDIMGDTLYEQSIVTYVAKFLQHSPELEAXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXQSPPPPSKVLVCDQP---ES-----AMGIRLGGASGRA
LS-GSSNELMQQIIDQVLQGGLCKT-SDVTEPSPESSILSSRKDGRRSNSLPIKKTVHFD
FEADAFKDASCSKDSFHGQDFHFDGSPRRAKK-L-KQDGHVLAREADEEKKLKLED-PET
TDTASDEPPDD-VSLVDSKVS-D-SQPPQGSSSWNGALEST-ASHQEGSPSFSSLEENTV
-IADSLEIKVK-LLSIEAMDEEGCFEGIPLKASKFSSDLVDFASTSHPFNEDPSPQEEKP
AE--NDVSEECVEKMGKRRAESAHKWKESAELPVKSDQYQPHWGP------------GQE
A-QGSLAPEEAPMDPKPE--VCGKAKSKSPRCLGDEDE----GETE----------SLEE
DGDELPSSP-PSCSVSLETLGSHSEEGLNFKPSPPLSRISVIPHDLFYYPHYEVPLAAVL
EAYAEGAEDLKNE-EMDA--EEPECYLH-DLDSGEXXXXX------------XXXXXXXX
XXXXXXXX-XXXX-----------------------------------------------
-----------------XX----XXX-XXXXX-------------------X-XXXX---
----XXXXXXXXXXXXXXXX-XXXXX-XXXXXTSHSDSSIYIRQHTYRSLES--------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

------------------------------------------------------------
--EREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SSITEPSPESSILSSRKESGRSNSLPIKKTVHF-
-EADTYKDPFCSKNL----SLCFEGSPRVAKESL-EQDGHVLAVEVAEEK-EQKQESSKI
PES-SDKVPG-DVFLVEGTNS---NSQS---SSCNGALEST-ARHEEESHSLSPPGENTV
-MADSFQIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLIDFASTSQAFNKVASPHETKA
DED-AEAFENDAEKLGKRSIKSAPKKKDSPEPQVKMDKHE-PHQD-----------SGEE
AEGCPSAPEETPMDKKPE--VHEKAKRKSTRP-----HYEEEGEDDD-LQ--------GV
-GEELSSSP-PSSCVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLF-FPHYEVPLAAVL
EAYVEDPEDLKNE-EMDL--EEPEG-YMPDLD-----------------SREEEADGSQS
SSSSSVPG-QSLPSASDQV-LYLSRGGVGTTPALEPAPLAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NLENI-ANPLEENVMKE-SISSKKKEKRKHVDH
VESSLFVAPGSVQSSDDLEE-DTSDY-SLPSRTSHSDSSIYVRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAA-HEWDWFQREEL-------------IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLGKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTE--RSAA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDALNIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELETEDFLDSDKEIPIESTFVRIKETPS--
EQEGKVFVLTENGERAYTVNHETSHPPPSKVFVCDKP---ES-----MKEFCLDGVSSHA
PS-DSSAEFMHEIINQVLQGGIGNKSSSVNEPSPESSILASRKEGRRFNSLPIKKTVHF-
-EADTCREASCSRDPFYSQDFRFEGSPRAAQEVL-KQGGPSLAVEVLEEK-EPKQESAET
LEFPSGQLPGGDTSLADGESD---DSQSSPSSSCNGAPESA-ASPGEERHSLAALEENTV
-MADSMEIKVK-LQTVEDMDREDYFECIPLRASKFNSDLIDFASTSQAFKEVPSPHEKKP
AEG--EVFEANAEKLGKKRTKSAHKRKDSPEPQAKSEQQE-PPRG-----------PERN
VLGHSLALEEMPADIKPK--ACEKAKRKSTG-R--RGGGEEEGEAVG-LQ--------SI
-GEELPSNP-PSSSVSLETLGSHSEEGLDFNPSPPLSKVSVIPHELFYYPHYEVPLAAVL
EAYAEGSEDLKNE-EMDL--EEPEG-YLRELD-----------------SREEGGDGSHS
GYRSPVLG-KGTPGASDQE-LHLDSGGEGATPALEPAAPPPL-ED---------------
--HQQREAEE--RDPV-DSYQAQEPP-NSENI-ANPVEERVTEK-SISSKKKEKRKHVDH
VESSLFIAPGTVRSSDDLEE-DTSDH-RIPSRTSHSDSSIYIRRHTNRSLESDHCSYVQL
RNTADLDDRRNRILTRYNT-----------------------------------QKLTEL
ILQFYGIRADMKRECKHARMSMKEGQQLRRSHTAGEPQPTERLADTVSAAAGHDVLYPLP
VAPGVLPAALPTARRQQALMRVSAQ

--------------------MAA-HEWDW-FQREEL------------IGQISDIRVQNL
QVERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFNSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHESSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPIKKTVHF-
-ETDTYRDPSCSKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DIFLAEGTVN---NSQS---SSYNGALEST-ARHDEESHSLSLPGEDTV
-MADSFEIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLVDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRGKRSTKSAHKKKDSPEPQVKTDKHE-PHQD-----------SGEE
AEGSPSAPEDTPTNKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EEPEV-YMSDLD-----------------SREEEADGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPAPLAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIQRHTNRSSESDHFSFVQL
RNAADLDDRRNRMLTRYNT-----------------------------------QKLTEL
ILQFYGIRADMKRESKHA-------------------RKSMKV----FLA-----VGELL
A------------------------

--------------------MAA-HEWDW-FQREEL------------IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFIDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVVKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHKTSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSVLSSRKESGRSNSLPIKKTVHF-
-ETDTYKDPSCRKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DIFLAEGTIN---NSQS---SSYNGALEST-AHHNEESHSLSPPGENTV
-MADSFEIKVN-LMTVEALEEGDDFEAIPLKASKFNSDLIDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRDKRSTKSAHKKKDSPEPQVKTDKHE-PHQD-----------SGEE
AEGCPAAPEETPTDKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKHE-EMDL--EEPEV-YMPDLD-----------------SREEEADGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPAPPAPH-ED---------------
--HQQRETKE--SDPM-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGETM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------MPWGWAGDEQGF----KR---FAHSSLYPANGFSLF
SVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWVNL-HLEKCDPPLEVKDLFIDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGMAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFRVAHEALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDLVDSDKEAPIESTFVHIKETPS--
EQESTVFLLTENGERAYTVNHEASHPPPSKVFVCDKS---ES-----AKECYLSVMPSQA
LS-DSSTDFMHQIIDQALQEVPGKA-SSTGEPSPESSILSSRKDNRRSNSLPIKKTVHF-
-EADTYKEASCSKDPFYSQDLRFEGSPRGTKDSL-KQDGDVLAAEIAEEKPKQEAPK--I
PEAASDESPGV-ESLVDKKIN-H-SQTSESCPSWNGAPEGE-AGGGKESRPLSPLGDNAV
-MADSLEIKVQ-LLTVEAMAEEDYFESTPLKASKFNSDLIDFASTSQAFNEVPPPREKRP
VE--EEVPEDHAEKLGKRRSKSVHQRKDSDESPERPDKQEPHKDP------------GRE
DPGYSLAPEEAPVEKKPE--AYEKPKRKSARRRRGEDE----GEAAGPQGPD--------
--GELPSDP-PSGSLSLETLHSRSQEGLDFKPSPPLSKVSVIPHDLFYYPHYEVPLAAVL
EAYAEGSEDLKHR-DLDL--EEPEDYLH-DLGAGAEAEEA------------EEAEGSWN
SCSFSGPD-EEGPEASIPA-PSTDRGAEGTRPASEPAPPAPP-EG---------------
--HQPGEAEE--SGPV-DSHQSQESE-NSGNL-ANSLEEKVTGE-SISSKKKEKRKHVDH
VESSIFIAPGTVRSSEDLEG-DTGDH-KVLSRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADQDDGRNRML-----------------------------------TRKANDSGEAV
FQESRTSQSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVTRL---------------

--------------------MAA-HEWDW-FQREEL------------IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFIDIQDGKILMALLEVLSGRNLMHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVVKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHKTSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSVLSSRKESGRSNSLPIKKTVHF-
-ETDTYKDPSCRKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DIFLAEGTIN---NSQS---SSYNGALEST-AHHDEESHSLSPPGENTV
-MADSFEIKVN-LMTVEALEEGDDFEAIPLKASKFNSDLIDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRDKSSTKSAHKKKDSPEPQVKTDKHE-PHQD-----------SREE
AEGCPAAPEETSTDKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EEPEG-YMPDLD-----------------SREEEADGSQS
SSSSSVPG-ESLPSASDQV-LCLSRSGAGTTPASEPAPPAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGETM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
-----------------------

PF00307 // ENSGT00900000140842_0_Domain_1 (84, 174)

CNPPLEVNDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPALVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLSRNSPSLSLSPGSGGTDSDSSFPPTPTTE--RSAV--LSLKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIKTLLSWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSSRENLEKAFSTAQDFLHIP
RLLEPEDIMVDVPDEQSVVTYVAQFLERFPALEAEDVVDADAEAPIESTFVRIRETPS--
EQESPIFLLTENGEQTYTVSQEVSQPPPAKVFVSDRP---ESKAFRF----------PRG
RS-ATSSELVHQLIDQVLQGSPCKA-SDSSEPMPETSILASRKDNRRANSLPVKKTVHF-
-ETDLYKDASCSRDPRLSLNL----TPRGAKDPL-RQDSQVVAGEVEEGKNPKPEA-PKA
PEAAPS---REGVSSAGDKLG-------DPQTSCNGALERAEDPLGEEHS--PPLRREDL
-AADPVEIRVQ-LLSVDPPDSEDSFEGIPLKASKFNHDLVDFATTSQAFREVPSSPEPAA
S-------QGRPEPRGKRSKKRAGRKKGPPEAAPEPQ------------------GPGED
AGARPSAPKEAPADRKRE--VCEKAKCKSARRGREEEE----E--------------DDD
EDRELPCNP-PSSSVSLETLGSHSEDTLDFKPSPPLSKVSVIPHDLFYYPHYEVPLAAVL
EAYTEGAEEEGKREDLEL--EDPDGGLQ-DLDFREEE-----------------AGDSLG
SCSFVVTG-QDLRGDKGQL-PYHEEGATGAREAR---PAVD-------------------
--HLDRSAQE--RDTWESSHQXXXXXXXXXXX-XXXXXXXXXXX-XX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXDHFSYVQL
RSVAELDDRRNRIS-----------------------------------TRKANHSGEAM
LPGNQNLPSDSLTQLVQ--------------------QPDVMY----FILFLWLLVYCLL
LLPQLDISSL---------------

--------------------MAA-HEWDWFQREEL-------------IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFIDIQDGKILMALLEVLSGQNLLHEYK
CSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTERERSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFRIAQDALHIP
RLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFYSDKEVPIESTFVHIKETPS--
EQESKIFVLNENGEHTYTINHETSHPPPSKVFVCDKP---ES-----MKEFRLDGISSHA
LS-DSSTEFVHQIIDQVLQGGPGDT-SDISEPSPETSILSSRKESQRSNSLPIKKTVHF-
-EADSCKDASCSKDL----SLHFEGSPRVAKEPL-MEDGHILAVEVAEEK-EWKQESLKI
PESFSDKVPG-DVFFAEGTIN---NSQSS--SSYNGALEST-ASHDEESHSLSPPGENTM
-MANSVEFKVN-LMTVEPLDEEDYFEAIPLKTSKFNSDLIDFASTSQAFNKVPSPHETKP
DED-DEAFENHAEKLGKRSTKSAHKEKDSPEPQVKSNKHE-AHQD-----------SGEE
AEGCPSAPEETPTDKKPE--VYEKAKGKSIRP-----HDEEEGEDGD-LQ--------GV
-GEELSSSP-TSSSVSLETLGSHSEEGLDFKPSPPVSKVSVIPHDVFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EGPEG-CMQDLD-----------------SREEEADGSQS
SCSSSVPG-ECLPSASDQV-LYLNRDGGNTTPASEPAPLAPH-ED---------------
--HQQRETKE--SDPM-DSHQSQESP-NPENI-ANPLEEKVTKE-PISSKKKEKRKHVDH
VESSLFIAPGTVRASDDLEE-DTGDH-SVPSRTSHSDSSIYIRRHTNRSLESDHFSHVQL
RNTADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSLQSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAA-HEWDWFQREEL-------------IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPIEVKDLFIDIQDGKILMALLEVLSGRNLLHEYK
CSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTERERSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSARENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKIFILNENGEHTYTINHETSHPPPSKVFVCDKP---ES-----MKEFHLDGISSHA
LS-DSSTEFMHQIIDRVLQGGPGDT-SDISEPSPETSILSSRKESQRSNSLPIKKTVHF-
-EADTCKDASCSKDL----SLHLEGSPRVAKEPL-MEDGRILAVEVAEEK-EWKQESSKI
PESFSDKVPG-DVFFAEGTIN---NSQSS--SSYNGALEST-ASQDEESQSLSPLGENTA
-MASSVEIKVN-LMTVEPLDEGDYFEAIPLKASKFISDLIDLASTSQAFNKVPSPHETKP
DED-DEAFENHAEKLGKRSTKSSHKQKDSPEPQVKSDKHE-AHQD-----------SGEE
AEGCPSAQEETPTDKKPE--VHEKAKRKSIHP-----HHEEEGEDDD-LE--------GV
-GEELSSSP-PGSSVSLETLQNHSEEGLDFKPSPPVSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-KMDL--EGPEG-CMQDLD-----------------SREEEADGSQS
SCSSSAPG-ECLPSASDQV-LYLNRDGGSTTPASEPAPLAPH-DD---------------
--HQQRETKE--SDPM-DSHQSQESP-NPENI-ANPLEEKVTKE-SVSSKKKEKRKHVDR
VESLLFIAPGTVRSSDDLEE-DTGNH-RVPSRASHSDSSICIRRHNNRSLESDHFSSVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
--EREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLGKCNPPLEVRDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDALSIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELETEDFLDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERAYTINHETSHPPPSKVFVCDKP---ES-----IKEFCLDGVSSHA
LS-DSSTEFMHEIIDQVLQGGVGKT-SGIGEPSPESSILSSRKDSRRFNPLPIKKTVHF-
-EADTCKEASCSKDPFYSQDLRSEGSPRAVQEVP-KQGGPSLAAEVPEGK-EPKQESAET
PEFPSDQVPS-DISLEDGTID---NSQISLSSSCNGAQESA-ASHGEESHSLAPLEENTV
-MADSVEIKVK-LQTVEDMDKEDYFEGIPLKASKYNSDLIDFASTSQAFNEVPSPHEKKP
AEG--DVFETNAEKLGKKRTKSAHKKKDSPEPQVKSEQQE-PPQG-----------PEQN
IQGHSLALEEIPVDIKPK--VCEKAKRKSTG-R--PRGGEDEGEAEG-LQ--------SI
-GEELPSSP-PSSSVSLETLGSHSEEGLGFKPSPPLSKVSVIPHELFYYPHYEVPLAAVL
EAYAEGSEDLKNE-ETDL--EEPEG-YLHDLD-----------------SWEEEADGSHS
GYSSPVPG-EGLSGARNQV-PHLDTGGEGATPASEPAAPPPH-ED---------------
--HQQREAKE--RDPV-DNYQSQEAP-NSENT-ANPEEEKVMEK-SISSKKKEKRKHVDH
VESSLFVAPGTVRSSDDLEE-DTSDH-RIPSRTSHSDSSIYIRRHTNRSLESDHCSYAQL
RNTADLDDRRNRILTRKAN-----------------------------------NSGEAT
LLESHSPRSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

-------------------------------------------------------RVSLF
SEEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVKDLFIDIQDGRILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLSRNSPPSSLSPGSGGTDSDSSFPPTPTAE--RSAA--LSVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIRTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKAALEDSMPENLEKAFRIAHDALHIP
RLLEPADIMVDTPDEQSIVTYVAQFLEHFPELEAEDFVDPDKDAPIESTFVRIKETPS--
EQESTVFYVTDDGERAYTVNHDTSHPPPSKVFVCDKP---AR-----GKDSRPGGAPGPT
PA-NSPAEVTPQGTDWDTLGASGRT-CSLSEAPPESSIL-SRKDNQRSSSLPGKKTVHF-
-EADVYKDASCSKDPVHSQDCGFEGGHRGTKDLW-KQDGHGPE--VAEERPR-----HDA
PEAAPDQALDD-VCLADSQTG-P-SQTPQGSAPRNRASERP-ASPGEESCPRARLGEETV
-MADSSELKVK-PQTAEAMDEEDDFEGIPLKASKFNSDLVDFASTSQAFGEDPPPAEDGP
AE--AGAAEAQAENLGNGRSTSAPRMEGADEPPGKP---------------------GHE
DHSRVVAPEEEPGGRKPE--VYEKAKRKSPRPPRGEEE----AEAEDPPA----------
FEGDLPSNP-PSSQVSLETLGSHSEEGLDFKRSPPLSKVSVIPHDLFYYPHYEVPLAAVL
EAYAEGQEDFKAE-DADF--EDPEDYLS-DLEQREDEDEP---------------EASES
SGSFRGLG-EDRPQPPTQE-PDRDQGAQGAKPASGPPPTLAP-ED---------------
--HQQREATA--RAPG-ESQQSQESP-NSENL-RNPLEEKVMEE-SVSSKKKEKKKHVDD
VESSVLLTPGAVRSSDDLDE-DPGFH-RVPSRTSHSDSSIYIRRHTNRSLESVSM-----
RLSSSSERHWNFTVGSYNTQRLTELILQFYGIRADMKRE---CKHARM-SMKANHSGEAS
LRESQSPRSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
-------------------------------------------MALLEVLSGRNLLQEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSLA--VAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGMAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAHEALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFMDSDREAPIESTFVRIKETPS--
EQESTVLLLTENGDRAYTVNHEASQPPPSKVFVCDKP---ES-----EKECFLSGVSSHA
LS-DSSPEFTPQIIDQALQGVPGKA-SSTNDPPPESSILSSRKDSRRSNSLPIKKTVHF-
-EADTYKAASCSKDPFYSQDLRFEGSPRGTKDSLPKQDGYILAVETAEEKPKQEVP--KG
SEAASDESPGD-ISLVDGKIN-H-SQTAQSSPSWNGEPEGA-ASPREESCPLSPFGDNTV
-MADSLEIKVK-LLTVEAMSNEDYYEDVPLKASTFNNDLIDFASTSQAFKEVPWPHEKKP
AE--DEVLENQSEKLGKRRSKSAHQRKGSDESPERPSKLEPHKDP------------RQE
DQSHSLAPGEAPADKKPE--VYEKPKRKSTRRHLDEDE----GEVVGL----------QG
PEGEAPSEP-PSSSVSLETLHSRSEVGLDFKPSPPLSKVSVIPHELFYYPHYEVPLAAVL
EAYAEGAEDLKNE-DLDL--EEPDGYLC-DVAARDEAEEAEEVEETEEAEEVEEAEVSQS
SCSFSGLG-EDVPEASFPAVPCPAGGVENTRLTSEPADLSPP-DD---------------
--HQQGEAED--SSHV-ENQQSQEFG-NQGNL-ANSLEEKVMGE-TISSKKKEKRKHVDH
VESSIFIAPGSVRSSEDLEE-DPGDH-KVLSRTSHSDSSIYIRRHTNRSLESDHVSYVQL
RNAADLDDRRNRTLTR-----------------------------------RANNSGEAT
LLESQRPQSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
----------------------------------M

PF00307 // ENSGT00900000140842_0_Domain_1 (96, 174)

DIQDGKILMALLEVLSGQKLMHEYK
SSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLNRNSSSSSLSSGPSGPESDTSYPSTPNIE--RSMS--VTVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

RALLFWVQRKT
RKYGVAVQDFTSSWRSGLAFLAVIKAIDSTLVDMKHALEKSARENLEDAFSIAQNKLGVP
RLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPEKELPIESTYVHIKDTPS--
EKESKILILRESDKNMYTVNHERSHPAPPKVHIHDTP---ERILSETVPEACNGKLSQ--
------------------------V-LG-------DSQEISEDEPQRPTSLKITGSASY-
-ESSSSWEVLSD--KLMPGDGGISDDP------L-KQSDDLSPAVLTDQ-----------
------------------KNS-V-------------DS----------------------
-----FEDYSE-ELTKETYTEYDN-ETKSLSANTSSLSPLSWTSVTDSLHEEGAPAQD--
----------------------------YKEDAPEPGLQNNHGVP--SLEM---G-TE--
--------------------NG--------------------EEETIDMNSHSTSF----
YEKEVP--L-LIGEIEIEIDSQKATGNE--------DSMILQHPEVIGDNLDDFAIVGVR
--LE--------------------------------------------------------
------------------------------------------------------------
-----------------ESSNGDEKKENMIK--------------------VEELQT---
-----SEVGHTALFDDE-LE-EIANS-QELTRTCDNDSNIYLRKRFPDTAGLETSGKK--
-DQ-KMTEVDE--------------NLLIIGLKKDMETN---ET----------------
------AAPPRQTPSVE--------------------QSELFY----LIIFLWVLVYCLL
VLPQLFSFKV---------------

------------------------------------------------------------
--ERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCKPPLEVKDLFLDIQDGKVLMALLEILSGQKLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLNRNSSSSSLSSGLGGTDSDSSHPTTPSTE--KNVA--VSVKDQRRAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RALLAWVQKRT
RKYGVAVQDFAASWRSGLAFLAVIKAIDPTLVDMKQALEDSARENLERAFSVAQDRLHIP
RLLEPEDVMVDTPDEQSVMTYVAQFLEHFPELEGEDVPDPDKEFPIESTFVHIKETPV--
EQEGKIFVLNENGQRAYTINHETSQPPPPKVFVCDAP---DSSNFEISH-----------
VS-DNSNNQTSPFTDQFIPGCSKKS-ADFNQSLSEPSVLLPKKEIQRPNSLPIMSSDHF-
-ESDTCEQVLENKLAPNKWNESSLNEP------L-EQKSCLSPTVVTDEKNTIL-PAD-S
FE------VDS-EQLKDEKHA-VERARYSEG--NSEHLASE-ASPESSDNVDTTANKVLD
-DPLSASVKKA-IVIPDSLEDNVK--QLERTGSLEQVEIIDLTGSNITPDDFPSTYGERS
TV--ANSSENDADELVRKGSKSISEATGSTSI--SPCDNGPPGTAFITSDTPSIEPPNPG
L----------------E--QGERIQQESAGQTKRECG----GVEDAGPEGSGASPRDRE
DNISISSQS-VVSLKDIHVQESQQGDGA-DLMATSSSKVSVIPHDLFYYPHYNVPISAVL
EAFADSSSSPDGS-KSG-------GTLP-ETSGTVRE-----------------GEEEQA
ARPVLANY-SYQN-AFICS-FVHP---SDFMDTSLPEHPTSI-SGLSGSGYEDGESGGLP
VVKREGIPDK--REGV-SERQMFQAIENMDQLE-ATL-ETLLGE-AISSKKKEKRKHVEK
REMLKIAAATPAYLPDDPED-EITDH-KMFSRASHSDSSIYIRRDANKPVDADHFNRKES
RKS-DTEERRHLII----------------------------------------------
------------------------------------------------------------
-------------------------

MPCQPRSGKVSKPFRTGKVSISGLSILQRFCRLSPLGRGGQG---FARISFHPANGISLF
SVERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAHDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFVDSDKEAPIESTFVRIKETPS--
EQESAIFLLTEDRERAYTINHEASHPPPSKVFVCDKP---ED-----VKEPCLGGVSSQE
LE-DSSSELMNQIIEQVLQGIPGKL-NSTSEPAPESSILSSRKDSRRSNSLPIKKTVHF-
-EADTYKDASCSQDPFYSADLRFEGSPGETRDLS-EEDEQVLAADIAEEMPKREAP--EI
LEAASDEAPGD-VSSVDGEIS-H-PLTSWTSAPWNGASERA-SSPGDEGHLPSPLGENTV
-MADALEIKVK-LLTVEAMDKEDYFEAIPLKASKFNSDLIDFASTSQAFNEVPSPHEKKP
AE--EELSEDHPERLEKQRGKSACKKTDSDEAPVKLDQPDPHKDP------------GDQ
DQGYSLAPEEAPVDKKPE--VYEKAKRKSFRRRRRGEE----EGEAEC---------LRG
LGGELPSNP-PSSSVSLETLRSPSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGSEDLKNE-EMDL--EEPEGYLL-DLGAREDEA-----------DEADDAEASQS
SFSFSGLG-EDLPQASIV---------EDASPASEPSPQPSP-ED---------------
--HQQREAKN--SVPV-QGHQSQESP-NSENL-ASPLEEKVMEE-SISSKKKEKRKHVDH
VESSIFVAPGTVRSSDDLEE-DTGDH-KVLSRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADVDDRRTRMLTR----------------------------------K-ANHSGKAR
LREIQSSQSDSLTQLVQ--------------------QPDVMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
--EREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSAV--ISVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

RAIRTLLTWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAHDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFADSDKEAPIESTFVRIRETPS--
EQESTVFLLTENGERAYTVNHETSHPPPSKVFVCDKP---EG-----VKEPCV---TSQE
LA-DSCSEFMHEIVDQVLQGVPGKI-NSTGELAPESSILSSRKDSQRSTSLPIKKTVHF-
-EADTYKEASCSRDPFYSPDLRFEGSPRETKELS-RQDGQVWVAEVAEETTKQEALE--I
LEAASSEAPSD-VSSVDGKVS-H-PPTSQTSPSWNGVSERA-AGPGKEGRSPSSLVEDTI
-VADSMEIEVK-LLTVEAMDKEDPFEGIPLKASKFNSNLVGFPSTSQAFHEVPSPHEKKP
AE--EEVSEDRAEKLRKRRGKSTHRKTDLDEPPVKPNQQEPHKDP---------GPE---
DRG---SSLEAPVDKKPE--VCEKAKHKSPRRRRGEEE----E--AEGPRGLGELPS---
----------SPHSSRSETLRSPSDEGLDFEPSPPPSRISIIPHDLFYYPHYEVPLAAVL
EAYAEGVEDLRNE-EVDL--EEPEGYLP-DAGAGEAE-------------------ASQS
SCSFAGR-----G-KGHPQ-ASVA---EDASPASEPSPPSPQ-GD---------------
--HQPSEDAE--SVPV-QGHQSQEFP-NSENL-ANPLEEKVMEE-PISSKKKEKRKHVDH
VESSIFIAPGTVRSSDDLEE-DTCDH-KVLSRTSHSDSSIYVRRHANRSLEPDHFSHVQL
RNAADQDDRRNQML-----------------------------------SRKANSSGEAR
TQETHSPESDSLMQFVQ--------------------QPDVMY----FILFLWLLVYCLL
VFPQLDLNGL---------------

--------------------MAG-HEWDWFQREELI----GQ---ISD------IRVQNL
QVERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCNPPLEVKDLFIDIQDGKILMALLEVLSGQSLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLNRNASSSSLSSGPPGPDSDSSLPATPKGE--NSVA--LSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RTLLNWVQRRT
RKYGVAVQDFAGSWRSGLAFLAIIKAIDPSLVDIKQALENSARENLEKAFSIAHDKLQIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPGLEGEDFMDPDKEIPIESTFVRIKETPT--
EQEGKIFLLTENGEHTYTINCETSQPPPPIVFVCDNP---EV-GKELVTDESPSDSSSRR
YS-DSPENELSYIAEQVFPGGFNKP-NDINESLSEPSILISKKADHRPDSLPVKKSVHF-
-ESDVSKDASCSKDINFKGDSEMINET------L-AQDDSVSSSGVCNKIKFKE-GRMKS
LGSALNKILDD-YPLTHKKNG-G-------------FSTSD-ILPGNAEEDVEANEGNDA
-HPHSSEIRDE-KVIQKALVEAGGFEEMAVKATTAHSPE----MKDQTLRDENSAPVEKN
VARDGVSSKANVKQLTKKASKCHHKMKDSTADNSDTDLRSSEVPTVDSRDSSLVT-PDED
IYNYVLHLQEEAVMTELD--VSEKAKQQ-----PVNKD----QEEKAPPDNHLEIQEDVE
DEFSTP-----LSSVSLETLGSQSEDSLDLKLSPPSSKVSVIPHDLFYYPHYDVPLSAVL
EAYVEASHGS----QNE-------EIVP-EKSTEDAQELD------------TTGEDPQK
GCKSNSSF-LVTE---------LS---AEVPQMDLPSHPAET-EPSSET-----VEKKSH
VEHKGKDPPN--TDSV-DNSQSQDFQ-NVGKL--DVSLEKLPEE-ATSAKKHEEWNHGDQ
AESSLFVAARAAHFSEDLEE-EIIDH-KVISRTSHSDTSLYIRRQSNKPSEMDHYSHARL
RPT-EMEERRNR-LFRYHSKKLPELIFQVYGIKTSEEGMQKYKEVFEIILLKANNFGEAM
-LHGHHGASDSLVHFAQ--------------------QQDLVY----FILFLWLLVYCLL
LFPQLDIKKL---------------

--------------------MAA-PEWDWFQREELI----GQ---ISD------IRVQNL
QVERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWVNL-HLEKCNPPLEVKDLFIDIQDGKILMALLEVLSGQNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTE--RSTVISLSVRDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

KTLLAWVQSKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDTTRENLEKAFRLAHDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFVDSDKEFPIESTFVRIKETPP--
EQESQVLLLTENGECAYTINHETSHPPPSKVFVCDQP---ET-AKDLQLQPCPGDTAGHA
RS-GSSNELRHQIIDQVLQGS------DVTESPPESSILSSRRESRRSNSLPIKKTVHFD
FEDNTYRDVSCGKDSSYNQDLQFDGSPRRAKKLL-KEDVL--AKEMDEEKNSKEE-APKT
VKVGSDEPPDA-ISLVGSEYS-D-FPTCQGPSSHNGALEST-ADPKEESCSPPLLGEDTV
-MADSLEIQVK-LLTVEVMER-DDFEGIPLKASKFSSDLVDFASTSHAFHEVPSPQEEKP
AE--NDVSEECVEKLGKRKAKSARRRKDSAERSDEPQLHRGPGQ----------------
EPQGPLASEEAPVGQKPE--VCEKAKFKSARHRGGEDE----GEAEALEG----------
DDGDLPSTP-PSCSVSLETLGSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGAEELKNE-GMDP--EDPEGYLH-DLDTREEE-----------------ADDVRS
GCSSSVTS-EDLAGASSQG-LYLGRDALGTHPATDPGPPAGH-TD---------------
--HQLGEAGESGQAPA-ENNQSQESP-NSGNL-ANSVEEKVMEE-SISSKKKEKRKHVDH
IESSIFIAPGTVRSSDDLED-DPTDH-RVPCRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADLDERRNRMLTRYNTQKLTELILQFYGIRADMKRE---CKHARM-SMKASHPGEAT
LRE--SLQSDSLTQFVQ--------------------QPDVMY----FILFLWLLVYCLL
LFPQLDINRL---------------

MPCQPRSGKVSKPFHTGKVSISGLSILQRFCRLSRLGRGGQG---FARISFHPANGISLF
SVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAHDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFVDSDKEAPIESTFVRIRETPS--
EQESAIFLLTEDRERAYTINHEASHPPPSKVFVCDKP---ED-----VKEPCLGGVSSQE
LE-DSSSEFMNQIIEQVLQGIPGKL-NSTSEPAPESSILSSRKDSRRSNSLPIKKMVHF-
-EADTYKDASCSQDPFYSADLRFEGSPGETRDLS-KEDEQVLAADIAEETLKREVP--EI
LEAASDEAPGD-VSSVDGEIS-H-PLTSWTSPPWNGASERA-SSPGDEGHLPSPLGENTV
-MADALEIKVK-LLTVEAMDKEDYFEAIPLKASKFNSDLIDFASTSQAFNEVPSPHEKKP
AE--EELSEDHPERLGKQRGKSACKKTDSDEAPVKLDQPDPHKDP------------GDQ
DQGYSLAPEEAPVDKKPE--VYEKAKRKSFRRRRRGEE----EGEAEC---------LRG
LGGELPSNP-PSSSVSLETLRSPSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGSEDLKNE-EMDL--EEPEGYLL-DLGAREDEA-----------DEADEAEASQS
SFSFSGLG-EDLPQASIV---------EDASPASEPSPQPSP-ED---------------
--HQQREAKD--SVPV-QGHQSQESP-NLENL-ASPLEEKVMEE-SISSKKKEKRKHVDH
VESSIFVAPGTVRSSDDLEE-DTGDH-KVLSRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADVDDRRNRMLTRYTTQKLTELILQFYGIRADMKRE---YKHARMSMK-ANHSGKAR
LREIQSSQSDSLTQLVQ--------------------QPDVMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

-------------------------------------------------------RVSLF
SVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFIDIQDGRILMALLEVLSGQNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLVWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLSRNSPSSSLSPSSGGTDSDSSFPPTPTAE--RSAA--LSLKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIKTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDALHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLEHFPELEAEDFVDSDKEFPIESTFVRIKETPP--
EQESKVFLLTENGERAYTVNHETSHPPPAKVFVCDKP---ES-VKGLQLQPCLGGASSGA
LP-DSPCNLMHWSTE---QGVPYKA-SDVSEPSPETSILSSRKDSRRASSLPTKKTVHF-
-KADIYKDASCSRDPFYSQGVGFEESLRGAKDSL-KQDGHTMANEADEGKKPKQ-DALKT
LEAASNKAPDD-VSLAEGELS-G-SQSSQGTPAWNGAPDNT-ADHMGESHSVASAGESTI
-VADSLEIKVQ-LLSVEAVEKEDSFESIPLKASKFSRDLVDFASTSYAFDETPSLPENEA
TE--SDASEDHVEKLGKRRAKSAHKNKEPFTPQLPSDEHEPHKDP------------GQD
VPGSSLAPEEAPVDRKPE--VHEKAKRKSTRRGGE-EE----GEE----------ERFLE
DEGELPSNP-PSSSVSLETLRSHSEEGLDFKPSPPVSKVSVIPHKLFYYPHYEVPLAAVL
EAYTEGAEDLRNE-DADL--EDPDDYLQ-DLDSREEE-----------------ADDSQS
GCSFLVTG-EDLPGASDQL-PSLTRGPVGTQPAPDPMSPAHH-ED---------------
--HQQGEAKK--NDRT-YSQQSQKSP-NSEDS-ANPVQEKVTEE-PVSSKKKEKRKHVDH
VESSIFIAPGTVRSSDDLEE-DAPDH-KILSRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADVDDRRNRMLTRYNTQKLTELILQFYGIRADMKRE---CKHAR-KSMKANNSGEAV
LPGSHSPLSDSLTQLVH--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
-VERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCDPRLEVKDLFIDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSAA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFRIAHDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFVDSDKEAPIESTFVRIKETPS--
EQESTVFLLSENGERAYAVNHEISHPPPSKVFVCDKP---ES-----VKECYLGGISSRT
LS-DSSSEFMHQIIDQVLQGVPGKT-ISISEPSPESSILSSRKDNRRSNSLPVKKTVHF-
-EADTYKDASCSKDAAYSQDFRFEGSPRGTEELW-KQDGHVLAVEVAEDKMKQDEPE--I
LEAASDEAPGD-ISLARGKIS-H-SETSQSPPSWNGALERA-ASQEEGGRPLSPLGESTV
-MADSLEIRVK-LQTVEAMDEGDYFEGIPLKASKFSSDLVDFASTSQAFNEVPLLHEKKL
AE--DEVLEDHGEKLGKRRAKSAQKEEDSDEPPVKLDMRDPRKDP------------ERE
DEDYSLAPEEAPVEKKPE--VYEKAKRKSPRRRQGEDE----GEAEGLRALGG-------
---ELLSNP-PSRTVSLETLQSHSEEGLDFRPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYTEGAEDLKNE-EMDL--EEPEEYLC-DLGSREE------------------AEASQS
SCSFSGLG-EDPSEAGFQA-PSLDRGADHARPASEPASTSPQ-ED---------------
--HQQREAEE--SAPV-ESHQ---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

------------------------------------------------------------
---RET

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINLPNLIRCDPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKEVTG
NLSRSSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIRTLLAWVQRKT
RXXXXXXXXXXXXXXXXXXX-XAVIAIDPSLVDMKQALN-SMRENLEKAFSIAHDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFVDSEQEAPIESTFVRIKETPS--
EQESTIFLLTENGERAYTVNHETSHPPPSKVFVCDKP---DS-----VKEHCLGGVSSQE
LS-DSSTEIMHQIIDQVLQGVPGKT-NDTSEPPPETSILSSRRDNRRSNSLPIKKTVHF-
-EADVYPDASCSDDPSYRQNFRFEGSPRATKELS-KQDGHVSAVEVAEETPKQEAP--KV
LEAASDKAPGD-VSLVDAKVD-H-SEAFQTSPSWDGASERA-GSREEESRPLSPLGDNTV
-MAESLEIKVK-LLTVEAMDKEDYFEGIPLKASKFNSNLTDFASTSQAFSEVPLPHENKP
AE--DGVLEDHLEKLGQSGDSAHHIG-ASEREPPEIEQHTPPQDP------------GAE
DQGCSSAPEEAAVDKKPE--VYEKAKRKSPHRHKGEEE----GDPD----------NTQG
LGGELPSSP-PSNNVSLETLQSPSEEGLDFRPSPPLSKISVIPHDLFYYPHYEIPLAAVL
EAYAEGSEDLKNE-DMDL--EESEGYLP-DLGSREEEA--------------DEAEGSQS
SCSFLGLR-EDLSWASH----------GDARPASEPAPPAPQ-GD---------------
--HQQREAEE--SAPG-ESHQSQEFP-KSENL-ANPLEAKVMEE-SISSKKKEKRKHVDH
VESSIFIVPGTVQSSDDLEE-DTGDR-KVPS-----------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSVA--VAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLSWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRDNLEKAFSIAHDSLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEDFVNPDKEAPIESTFVRIKESPS--
EQESRVLLLSENGERAYTVNHETSYPPPDKVFVCDQL---ES-----PTGFCLDSAPSHK
LS-DSSTEFMHEIIDQVLQGSMGKTG-SMAEPAPESSILSTRKDGRRSNSLPVKKTVHF-
-EADLHKDASCSKDPFYSSDFRFEGSPKATKELS-KQDGHVSLAEVSKEK-KPEQEAKLV
LEVASDKAPESTADGLDAVPQ-D-AQPSQDSSFCNGTVESP-SSQGEKGPSPPFPGDHTI
-LASSTELKVQ-LLTVEPMDKEDYFECIPLKASKFNKDLVDFASTSQAFGEDPSSHEKTR
GEE--EGSENHAEKPGKRKSKSPHAETESTESRLEPKELEPPPKD-----------PEQ-
DQGRALPPE-TPADKKPE--VYEKAKRKSTRH-----HNEEEGEAESGLS--------AV
-GEETPFIP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKSE-DADL--EHPEESYLQDSREEEAD------------EDEEEAHSSQS
SCSFSLPVDNSHPSVSDHV-SHVDGSSEEPTSALEPGSPPSH-ED---------------
--HQPKETKE--NGPV-ESQQSQEPP-NPELP-TKPLEEKLTEA-STSSKKKEKRKHVDH
VESSLFIAPGTVRSSDDLEE-NPSEH-KVPSRNSHSDSSIYIRRHTNRSLELDHFSYVQL
RNAADLDDRRNRVLNRYNSQKLTELILQFYGIRADMKRE---YKHARLSMTGTNSSGEAV
PLGNQSPPSDSLTQFVQ--------------------QPDVIY----FILFLWLLVYCLL
LFPQLDVSRL---------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFIDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSVA--VSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKRALEDSTRENLEKAFSIAHDSLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEDFVNPDREAPIESTFVRIKESPS--
EQESRVLLLSENGERAYTVNHETSHPPPAKVFVCDQS---EN-----EKGFCLSAVPSQS
LS-DSATEFMHQIIAQVLQETPGKAG-PTNEPAPESSILSSRKDGRRSNSLPIKKSVHF-
-EADMHKDASCSKDPFYSSDFRFEGSPRAAKELS-KQDGHVSFVEVTKEKK-TEQEARSV
PETASDKGPG-DIVGVDGMPY-H-GQPPQDPSFCNGTVESV-ASQGEKGLSPPSPGDHTI
-LANSTELKVQ-LLTVEPMEKDDYFEGIPLKASKFNRDLADFASTSQAFGEDPSTHEKAP
GEE--EGSENYAEKLGKRKSKSPHTETEAPESQEEPDSHEPPPRG-----------PKQE
DQEHPLPPEETPADKKPE--VYEKAKRKSTRH-----RSEEEGETEG-LS--------GV
-GGEMPSNP-PSTSVSLETLRSHSEEGLDFRPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKGE-EVEP--GEPEEGYLQDSREEE----------------EEEAHSSQS
SCSFSLPVDNGHPSVGDQV-SHVDGNSEGPITASGPESPSSH-ED---------------
--HQERETKE--DGLV-ESQQPQEPP-NPELP-TKPLEEKSTEA-STSSKKKEKRKHVDQ
VENSLFIAPGTVRSSDDLEE-NPCEH-KIPSRNSHSDSSIYIRRHANRSLELDHFSYVQL
RNAADLDERRNRVLNR----------------------------------TGTNSSGEAV
PLGSQSPPNDSLTQFVQ--------------------QPDVFY----FILFLWLLVYCLL
LFPQLDVSRL---------------

-------------------------------------------------LRPASDGMSLF
SVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKENGRSNSLPIKKTVHF-
-EADTYKDPFCSKNL----SLCFEGSPRVAKESL-RQDGHVLAIEVAEEK-EQKQESSKI
PESSSDKVPG-DIFLVEGTNN---NSQS---SSCNGALEST-ARHNEESHSLSPPGENTV
-MADSFQIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLIDFASTSQAFNKVPSPHETKP
DED-AEAFENHAEKLGKRSIKSAHKKKDSPEPQVKMDKHE-PHQD-----------SGEE
AEGCPSAPEETPVDKKPE--VHEKAKRKSTRP-----HYEEEGEDDD-LQ--------GV
-GEELSSSP-PSSCVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYVEDPEDLKNE-EMDL--EEPEG-YMPDLD-----------------SREEEADGSQS
SSSSSVPE-ESLPSASDQV-LYLSRGGVGTTPASEPAPLAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NLENI-ANPLEENVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSVQSSDDLEE-DSSDY-SIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRILTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVSRL---------------

--------------------MAA-QEWDWFQREELI----GQ---ISD------IRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRSLLHEYK
SSSHRIFRLNNIAKALTFLEESNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTAE--RNVA--IAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEESPQENLERAFRVAHDALHIP
RLLEPEDIMVDVPDEQSIVTYVAQFLERFPELEAEEFMDPDKEVPIESTFVRIRETPP--
EQESKVLLLTQNGERTYTVNHETSHPPPAKVFVCDRP---EG-----AQGPGPAGLPSSG
LS-DSSAEFVYQIIDQVLQTG------ATSEPAPEASVLSIRRDSRRPSLPPTKKTVHF-
-EDGTYKDPSGSQEPFYSPDFHFEGSPRPARELL-KQGWRASVEDDTEEGKPEEAA-SLI
PEAASSEVPGT-YELVS-----P-VQPPQDSSSFNGALEGP-ASRGEESPTLLPPGVNTV
-LANSMEIKVK-LQTAEPLGNEDCLEGVPSHAAKFISDVLDFASYSQGEAP----SGEHA
AGEDGEAA----------------SGNCVQEPRVGCDRHEPPTGS------------GQE
SPSYSSSLKETPVDRKPATLVCEKAKRKSPRHRSED------EEEASGPPGLA-------
--EELSCSS-LRTSISLETLGSPSEEGLDFKPSPPLSKISVIPHDLFYFPHYEVPLAAVL
EVYSEGTEDVRDK-----------DCLP-DLDPGED------------------AEGSWS
RCSFSALG-EDLPRASSQE-LSPDRLITVATPASEAAPPALH-EN---------------
--QQPGETKG--SEPA-ESHQSQEFP-DSENA-ANSLEEKVMEE-STSSKKKEKRKHVDH
VDNSLYRAPGMVQSSDDI-G-DVDDY-AVPSRTSHSDSSIYIRRHSNRSLESDHISFVQL
RNAADLDERRNRML-----------------------------------TRKPSSSGEAE
SLGTQSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVTRL---------------

-------------------------------MAAHEWDWFQREEL---IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPQLEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTDFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKENGRSNSLPIKKTVHF-
-EADTYKDPFCSKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAEEK-EQKQESSKI
PESSSDKVPG-DIFLVEGTNN---NSQS---SSCNGALEST-ARHDEESHSLSSPGENTV
-MADSFQIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLIYFASASQAFNKVPSPHETKP
DED-AEAFENHAEKLGKRSIKSAHKKKDLPEPQVKMDKHE-PHQD-----------SREE
AEGSSSAPEETPMDKKPE--VHEKAKRKSTRP-----HYEEEGEDDD-LQ--------GV
-GEELSSSP-PSSCVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYVEDPEDLKNE-EMDL--EEPEG-YMPDLD-----------------SREEEADGSQS
SSSSSVPG-ESLPSASDQV-LYLSRGGVGTTPASEPAPLAPQ-ED---------------
--HQQRETKE--NDPV-DSHESQESP-NLENI-ANPLEENVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSVRSSDDLEE-DSSDY-SIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLHDRRNRILTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVSRL---------------

--------------------MAA-QEWDWFQREE----------LIGQ---ISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFIDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRGSPSSSLSPGSGGTDSDSSYPPTPTTE--RNVA--VSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTMLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDTLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEEFVNLDREAPIESTFVRIKESPS--
EQESRVLLLSENGERAYTVNHETSHPPPAKVFVCDEP---EN-----EKGFCLGTVPSHK
LS-DSATEIMHQIIDQVLQGSPGRTG-PTNEPAPESSILSTRKDGRRSNSLPIKKSVHF-
-EADLHRDASCSKDPFYSSDFRFEGSPKVAKELS-KQDVPVSLVEVAKEKK-TEQEARP-
--TASEKGPG-DIVGVDGMPY-H-GQPPQDPSFCNGTVESL-ASHGEKGPSPPSPGVHTI
-LATSTELKVP-LLTVEPMDKDDYFEGIPLKASKFNRDLADFASTSQACGEDTSTHEKTP
GEE--EGFENYAEKLGKRKSKSPHAETEAPESQEEPDSHEPPPKG-----------PEQE
DPEHPLPPEETPADKKPE--VYEKAKRKSTRH-----RSE-EGEAEG-LS--------GV
-SGEMPSNP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKGE-DIEL--EEVEEGFLQDSREEE-----------------EEAHSSQS
SCSFSLPVDNGQPSVGDQE-SHVDGNSEGPTTASGPGSPSSH-EN---------------
--HQQRETKE--NGPV-ESQQPQEPL-NPELP-TKPLQEKSMGA-STSSKKKEKRKHVDQ
VENSLFIAPGTVRSSDDLEE-NPCEH-KIPSRNSHSDSSIYIRRHANRSLELDHFSYVQL
RNAADLDERRNRVLNRYNSQKLTELILQFYGIRADMKRE---FKHARL--NGTNSSGEAV
PLGSQSPASDSLTQFVQ--------------------QPDVFY----FILFLWLLVYCLL
LFPQLDVSRL---------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSVA--VAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLSWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRDNLEKAFSIAHDSLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEDFVNLDKEAPIESTFVRIKESPS--
EQESRVLLLSENGERAYTVNHETSYPPPDKVFVCDQL---ES-----PAGFCLDSAPSHK
LS-DSSTEFMHEIIDQVLQGSTGKTG-SIAEPTPESSILSTRKDGRRSNSLPVKKTVHF-
-EADLHKDASCSKDPFYSSDFRFEGSPKATKELS-KQDGHVSLAEVSKEK-KSEQEARLV
LEAASDKAPESAVDGLDAVPQ-D-AQPSQDSSFCNGTVESP-SSQGEKGPPPPSPEDHTI
-LANSTELKVQ-LMTVEPMDKEDYFECIPLKASKFNRDLVDFASTSQAFGEDPSSHEKTR
GEE--EGSENHAEKPGKRKSKSPHAETESSESRLEPKKLKPPPKD-----------PEQE
DQGHTLPPE-TPADKKPE--VYEKAKRKSTRH-----HSEEEGEAESVLS--------AV
-GEEIPSTP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKSE-DMDP--EHPEESYLQDSREEEAD------------EDEEEAHSSQS
SCSFSLPVDNSYPSVSDHV-SHVDGSSEGPTSALGPGSPPSH-ED---------------
--HQPKETKE--NGPV-ESQQSQEPP-NPELP-TKPLEEKLTEA-STSSKKKEKRKHVDH
VESSLFIAPGTVRSSDDLEE-NSSEH-KVPSRNSHSDSSIYIRRHTNRSLELDHFSYVQL
RNAADLDDRRNRVLNRYNSQKLTELILQFYGIRADMKRE---YKHARLSMTGTNSSGEAV
PLGNQSPPNDSLTQFVQ--------------------QPDVIY----FILFLWLLVYCLL
LFPQLDVSRL---------------

-------------------------------MAAHEWDWFQREEL---IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKENGRSNSLPIKKTVHF-
-EADTYKDPFCSKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAEEK-EQKQESSKI
PESSSDKVAG-DIFLVEGTNN---NSQS---SSCNGALEST-ARHDEESHSLSPPGENTV
-MADSFQIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLIDFASTSQAFNKVPSPHETKP
DED-AEAFENHAEKLGKRSIKSAHKKKDSPEPQVKMDKHE-PHQD-----------SGEE
AEGCPSAPEETPVDKKPE--VHEKAKRKSTRP-----HYEEEGEDDD-LQ--------GV
-GEELSSSP-PSSCVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYVEDPEDLKNE-EMDL--EEPEG-YMPDLD-----------------SREEEADGSQS
SSSSSVPG-ESLPSASDQV-LYLSRGGVGTTPASEPAPLAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NLENI-ANPLEENVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSVQSSDDLEE-DSSDY-SIPSRTSHSDSSIYLRRHTHRSSESDHFSYVQL
RNAADLDDRRNRILTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVSRL---------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_0 (67, 114)

VQKRTFTRWINL-HLEKCNPPLEVTDLFVDIQDGKILMALLEVLSGRNGPFRPL
RCRWLYIIL---HAHTSFTSSSSGRRSCRRKC----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

--------------------MAA-HEWDW-FQREE---------LI---GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHESSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPIKKTVHF-
-ETDTYRDPSCSKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DIFLAEGTIN---NSQS---SSYNGALEST-ARHDEESHSLSPPGEDTV
-MADSFEIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLVDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRGKRSTKSAHKKKDSPEPQGKTDKHE-PHQD-----------SGEE
AEGCPSAPEETPVDKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EEPEG-CMPDLD-----------------SREEEADGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPAPPAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSVA--VAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLSWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRDNLEKAFSIAHDSLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEDFVNPDKEAPIESTFVRIKESPS--
EQGSRVLLLSENGERAYTVNQETSYPPPDKVFVCDQL---ES-----PTGFCLDSAPSHK
LS-DSSTEFMHEIIDQVLQGSTGKTG-SIAEPTPESSILSTRKDGRRSNSLPVKKTVHF-
-EADLHKDASCSKDPFYSSDFRFEGSPKATKELS-KQDGHVSLAEVSKEKKKSEQEARLV
LEAASDKVPESTVDGLDAVPQ-D-AQPSQDSSFCNGTVESP-SSQGEKGPPPSSPGDHTL
-LANSTELKVQ-LLTVEPMDKEDYFECIPLKASKFNRDLVDFASTSQAFGEDPSSHEKTR
GEE--EGSENHAEKPGKRKSKSPRAETEAAESRLEPKKLEPPPKD-----------PEQE
DQGHALPPE-TPADKKPK--VYEKAKRKSTRH-----HSEEEGEAESGFS--------AV
CEEEIPSAP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKSE-DTDL--EHPEDSYLQDSREEEAD------------EDEEEAQSSQS
SCSFSLPVDNSYPSVSEHV-SHVDGSSEGPTSALGPGSPPSH-ED---------------
--HQPKETKE--NGPV-ESQQSQEPP-NPELP-TKPLEEKLTEA-STSSKKKEKRKHMDH
VESSLFIAPGTVRSSDDLEE-NSSEH-KVPSRNSHSDSSIYIRRHTNRSLELDHFSYVQL
RNAADLDDRRNRVLNRYNSQKLTELILQFYGIRADMKRE---YKHARLSMTGTNSSGEAV
PLGNQSPPNDSLTQFVQ--------------------QPDVIY----FILFLWLLVYCLL
LFPQLDVSRL---------------

------------------------------------------------------------
-------------------------------------------MA

PF00307 // ENSGT00900000140842_0_Domain_1 (106, 174)

LLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALSFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RNAA--IAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVVKAIDPSLVDMKQALEESPRENLEKAFRIAHEALHIP
RLLEPEDIMVDVPDEQSLVTYVAQFLERFPELEAEEFVDPDKEVPIESTFVRIRETPP--
DQESKVLLLTQNGERTYTMNHETSHPPPAKVFVCDRP---EC-------------STSSS
MS-DSSAEFVHQIIDQILQEGPGKT-GATSESTPESSILSTRKDSRRSSLLPTKKTVHF-
-EDGTYKDTSYSQEPFYSPDFRFEGSPRAVRELL-RQGRHASVEEDVEERKLEEAA-SLV
PEAGSGEVSRA-----DGTMG-H-TQPPQDSSSFNGSLEAP-ASHSEESPSLPPFGVKTV
-LADSVKIEVE-LQTAEAMQKD-FLEDVPSQA--VISSMVDLASTSQALGEAPSGEKAAG
EEE-------------------EASRNCAQEPPVRCDRHKPPTGS------------GRD
SPGYSVSPGETAVDKKPETPVHEKAKRKSPRHCSEDEE------EADGPPG---------
LGEELSSNS-LRGSISLETLSSPSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGREDERSV-DLEL--EEPMDCLP-DLEPSEDN-----------------AEGPLS
SCSFSGPG-QGLPSASNQV-LPPSRHTVVATPASGPAPPALS-GD---------------
--QQPREAKE--SNPV-GSHQSPKFP-DSENT-ANSLEEKVMEE-STSSKKKEKRKHVDH
VESSLYRAPGIVQSSEDLED-NIGDH-RVPSRTSHSDSSIYIRRHTNRSAESDHISFVQL
RNAADVDDRRNRML-----------------------------------TRKASSSGEAE
SLGSQSMPSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDINRL---------------

------------------------XEWDWFQREEL-------------IGQISDIRVQNL
QVERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPSPGGTDSDSSFPPTPTTE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDILDSDKEAPIESTFVRIKETPS--
EQESKIFVLTENGERAYTVNHETSHPPPSKVFVCDKP---ES-----MKEFFLDGVSGHS
LS-DTSTEFMHQIIDEVLQGGLGKT-TSINEPSPESSILSSKKDSRRYSSLPIKKTVHF-
-EADTCKEASCSKDPFYNQDFRFEGSPRATKDVL-KQSRPTLAVEVTEEK-EPKQESSET
LEFTSDQVPG-DVSLEDGTID---NSQSSPNSSCNGALESA-ASHGEESHSPAPLEENTV
-LANSLEIKVN-LMTVEDMDKEEYFEGIPLKASKFNSDLVDFASTSQAFKEVPLPHEHKP
TEG--EDSENEAEKPGKRRSKSAHRRKDSLEPQDESDYQE-PTQG-----------PGEK
LQGYS--PEEVSVDKKPE--VYEKAKRKSIHRH--PRGGEEEGEAEG-LQ--------GV
-GEDFPSNP-PSSSISLETLGSHSEEGLDFRPSPPLSKVSVIPHELFYYPHYEVPLAAVL
EAYAEGSEDLKNE-EMDL--EESEG-YLHDLD-----------------SREEEADGSYS
SCSSPVAG-EVLPSASSQL-SHLKRGGMGATPASEPAPPFSS-ED---------------
--HQQREAEE--HDPT-ESHQPQESP-KSENI-ANPIEEKVVEK-SISSKKKEKRKHVDH
VESSLFIAPGTIRSSDDLEE-DSSEH-RIPSRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADLDERRNRMLTRKSN-----------------------------------NSGEAT
LLESHSPRSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAA-QEWDWFQREELI----GQ---ISD------IRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALSFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RNAA--IAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVVKAIDPSLVDMKQALEESPRENLEKAFRIAHEALHIP
RLLEPEDIMVDVPDEQSLVTYVAQFLERFPELEAEEFVDPDKEVPIESTFVRIRETPP--
DQESKVLLLTQNGERTYTTNHETSHPPPAKVFVCDRP---EC-------------STSSS
MS-DSSAEFVHQIIDQILQEGPGKT-GATSESTPESSILSTRKDSRRSSLLPTKKTVHF-
-EDGTYKDTSYSQEPFYSPDFRFEGSPRAVRELL-RQGRHASVEEDVEERKLEEAA-SLV
PEAGSGEVSRA-----DGTMG-H-TQPPQDSSSFNGSLEAP-ASHSEESPSLPPFGVKTV
-LADSVKIEVE-LQTAEAMQKD-FLEDVPSQA--VISSMVDLASTSQALGEAPSGEKAAG
EEE-------------------EASRNCAQEPPVRCDRHKPPTGS------------GRD
SPGYSVSPGETAVDKKPETPVHEKAKRKSPRHCSEDEE------EADGPPG---------
LGEELSSNS-LRGSISLETLSSPSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGREDERSV-DLEL--EEPMDCLP-DLEPSEDN-----------------AEGPLS
SCSFSGPG-QGLPSASNQV-LPPSRHTVVATPASGPAPPALS-GD---------------
--QQPREAKE--SNPV-GSHQSPKFP-DSENT-ANSLEEKVMEE-STSSKKKEKRKHVDH
VESSLYRAPGIVQSSEDLED-NIGDH-RVPSRTSHSDSSIYIRRHTNRSAESDHISFVQL
RNAADVDDRRNRML-----------------------------------TRKASSSGEAE
SLGSQSMPSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDINRL---------------

------------------------MPWASVCPPPRISPWEGEGVIFHILLILPANGMSLF
SVERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCNPPLEVKDLFIDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFDLDKEVPIESTFVRIKETPS--
EQESKVFVLTENGER-YTVIHETSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPNKKTVHF-
-EADTYKDPFCSKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAEEK-KQKQESSKI
PESSSDKVPG-DIFLVEGTNN---NSQS---SSCNGALEST-AHHDEESHSLSSPGENTV
-MADSFQIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLIDFASTSQAFSKVPSPHESKP
DKD-AEAFENHAEKLGKRSTKSAHKKKDSPEPQVKMDKYE-PHQD-----------SGEE
AEGCPSAPEETPMDKKPE--VHEKAKRKSTRP-----HYEEEGEDDD-LQ--------GV
-GEELSSSP-PSSCVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAVNL
EAYVEDPEVLKNE-EMDL--EEPEG-YMPDLD-----------------SREEEADGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGVGATPASEPAPLAPY-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NLENT-ANPLEENVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSVQSSDDLEE-DTSDY-SIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FIVFLWLLVYCLL
LFPQLDVNRL---------------

------------------MPIIQ-ELWRPRQESPELE------AILDPISKTPAKKKRLY
CLEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFIDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRGSPSSSLSPGSGGTDSDSSYPPTPTTE--RNVA--VSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTMLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDTLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEEFVNLDREAPIESTFVRIKESPS--
EQESRVLLLSENGERAYTVNHETSHPPPAKVFVCDEP---EN-----EKGFCLGTVPSHK
LS-DSATEIMHQIIDQVLQGSPGRTG-PTNEPAPESSILSTRKDGRRSNSLPIKKSVHF-
-EADLHRDASCSKDPFYSSDFRFEGSPKVAKELS-KQDVPVSLVEVAKEKK-TEQEARP-
--TASEKGPG-DIVGVDGMPY-H-GQPPQDPSFCNGTVESL-ASHGEKGPSPPSPGVHTI
-LATSTELKVP-LLTVEPMDKDDYFEGIPLKASKFNRDLADFASTSQACGEDTSTHEKTP
GEE--EGFENYAEKLGKRKSKSPHAETEAPESQEEPDSHEPPPKG-----------PEQE
DPEHPLPPEETPADKKPE--VYEKAKRKSTRH-----RSE-EGEAEG-LS--------GV
-SGEMPSNP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKGE-DIEL--EEVEEGFLQDSREEE----------------EEEAHSSQS
SCSFSLPVDNGQPSVGDQE-SHVDGNSEGPTTASGPGSPSSH-EN---------------
--HQQRETKE--NGPV-ESQQPQEPL-NPELP-TKPLQEKSMGA-STSSKKKEKRKHVDQ
VENSLFIAPGTVRSSDDLEE-NPCEH-KIPSRNSHSDSSIYIRRHANRSLELDHFSYVQL
RNAADLDERRNRVLNRYNSQKLTELILQFYGIRADMKRE---FKHARLSMNGTNSSGEAV
PLGSQSPASDSLTQFVQ--------------------QPDVFY----FILFLWLLVYCLL
LFPQLDVSRL---------------

------------------------------------------------------------
-------

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGQNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVRLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSAGTDSDSSYPPTPTTE--RNAA--LSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDPMRENLEKAFSIAHDALHIP
RLLEPEDVMVDTPDEQSVVTYVAQFLERFPELEPEDFVDPDREAPIESTFVRIKETPS--
EQESRILLLPENGERACTVNHESSHPPPAKVFVCEQP---ES-----GKGFSLGTVSHPA
HA-DSNNEFMHQIIDQVLQDVPGRV-DPINEPAPDSSILSTRKESRRATSLPIKKSVHF-
-EADTYKDASCS---NYNPDLRFEGSRRATKELL-KPDGHVCSVGLTQEKKPDPE-ASPI
LEAPCDKAPGD-AARPDAPTP-P-ASAPQGSPFCNGTLESP-PSYGEETS---HPPLDVI
-MAESLEIKVK-LLTVEAMNKDDYFEGIPLKASKFNSDLVDFASTSQAFGELPSPQDKTP
EE--EEGTDSYAEKLRKRRAKSARIKFESPAPQEDSHEGEPPENP---------G--LEA
QDHHGAAPDQAPADKKPE--VFEKAKKKSTRRGSEDDA----E-AEAL----------VG
ISAELLSNP-PSANISLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYVEGAEELKNEDDVDL--DEPEGFLH-GLDSREE------------------AYSSQS
SCSFSSPD-EGHPSASRLA-PSPH-------------------K----------------
------ETKE--SGPE-DSQQTQDST-KSENI-ANPLETKVAGE-STSSKKKEKRKHVDH
VETSFFVAPGTVRSSEDLED-DSGDH-RVPSRTSHSDSSIYIRRHSNRSLETDHFSYVQL
RNAADVDDRRNRMLNRYNTQKLTELILQFYGIRADMKRE---CKHTRI-SMKANHSGEAM
LQGSQSPQSDSLTQLVQ--------------------QPDVMY----FILFLWLLVYCLL
LFPQLDMNRL---------------

-----------------------------------------A---GAH------VCISLF
SVERET

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLDKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALQFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSAA--LSGKDQRRAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFTGSWRSGLAFLAVIKAIDPSLVDMKQALEDSARENLEKAFSIAQEGLHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDVLDSDKDIPIESTFVRIKETPS--
EQESKVFVLTENGERAYTVNHETSQPPPSKVFVCDKP---EN-----LHEFCLGGVSHQA
GS-TGSSEDMDQAAHPVLQGDPSKT-SGVSELSSESSILSSRKDSRRSNSLPVKKMVHF-
-ETDAFKDTSRSQDPSHG-------RPRAPKDSQ-KLEGLGLAVEVAEKAALEEASS-GL
PDATSGEAPDDGVSWAEGVI-----PDTQPSP----SSEAA-AG-HGEEGPRSPPGENAI
-MAESWEIQVK-LQTVDAMDEEDFFEGIPLKASKFNSDLVDFASTSQAFDEDPSPREETP
TA--PQAPEDPAERRGKRRAKTAHRERGPPEPRVDADGLEPREG------------PGRG
TPDSSSAPEATPLGGEPE--RCEKAKGKSARP--GDED----KEEAPGPQ-------EQE
AGGDVPSGP-PSGSVSLETLGSPSDESLSFQPSPPLSKVSVIPHDLFYYPHFEVPLATVL
EAYAEGLGDLKDE-EVEG--EEPAGAAW-ERDSREE------------------AEAAQR
GLPFSRLD-EGLSGASDWV-PDPDRAVEDAALASGPAAPAPD-QD---------------
--HRPRETQE--SDPS-RE-----PP-NAA-STAGPLDAKAAAE-PVSSKRKEKRRHVGR
VESSLSVAPGPAQASDDLEY-AASDA-RIPSRASHSDSSIYVRQHANSSLESDHFSYVPW
RSAAELDDRGNRTL-----------------------------------TRKAKKLGAAA
-SPGHCPQSSSLTQLVQ--------------------QPDTLY----FILFLWLLVYCLL
LFPQLDVARL---------------

------------------------------------------------------------
----------------------------------I

PF00307 // ENSGT00900000140842_0_Domain_1 (96, 174)

DIQDGKILMALLEVLSGQKLMHEYK
SSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLNRNSSSSSLSSGPSGPESDTS-PSTPSVE--RNMS--ITVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RALLIWVQRKT
RKYGVAVQDFTSSWRSGLAFLAVIKAIDCTLVDMKHALEKSARENLEDAFSIAQNKLGVP
RLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPDKELPIESTYVHIKDTPS--
EKEGKILILSESEESMYTVNHERSHPAPPKVHIHDIP---ERIPSETTSENCNGKLSQ--
------------------------V-LD-------DLQGMSEEEPQRPTSLKITGPVSF-
-ESNSSWEVLND--KFMPGEGSISDDP------L-KQNDDLSPAVLTDQ-----------
------------------KNS-V-------------DS----------------------
-----FEEYSE-ELTKETPTEYDN-ETKSLSANTSSLSPLSWTSVTDVLHDQNLPEQD--
----------------------------HKEDAPEPDLENKLGTS--PSET---D-TE--
--------------------NS--------------------EEETTKTSSHVNSS----
DEKEVP--L-IVEELEIEEDGNKATNHE--------DSAIPLHPEVFYFILEDLPIAIKT
--PE--------------------------------------------------------
------------------------------------------------------------
-----------------ENSNGEEEEKNMIE--------------------E-NLQI---
-----SEVATT-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSMA--VSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDTLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEEFVNPDKEAPIESTFVRIKESPS--
EQESRVLLLSENGERAYTVNHETSHPPPAKVFVCDQP---ES-----AKGFCLGVVPSHK
LS-DSATEFMHQIIDQVLQGSPGKTE-SSTEPVPESSILSTRKDGRRSNSLPIKKSVHF-
-EADLHKDASCSKDPFYSSDFRFEGSPRAAKDLP-KQDSHGSLAEVAKEKK-TEQEARPV
PETASDRGPE-DIVGVDGVPH-H-DQPPQDPSFCNGSVE---ASQGEKDLSLLSPADHTI
-LANSTELKVQ-LLTVEPMDKDDYFEGIPLKASKFNRDLADFASTSQAFGEDPSPPEKTP
GEE--EGLENNTEKLGKRKSKSPHAETESPESQSEADKHEPPPKG-----------PEQ-
DQDHPLPPEETPTDKKPE--VYEKAKRKSTRH-----RSEEEGEAEG-LS--------GV
-GGEVPSNP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKGE-DL----GEPDEGYLQDSREE------------------EEAHSSQS
SCSFSSPIDNGHPSTGDQA-SHVDGTSEGPTSTSRPGSPPSY-ED---------------
--QQQRETKE--NGPV-ESQQPQEAP-NPELP-EKPLEEKSMEA-STSSKKKEKRKHVDQ
VESSLFIAPGTVRSSDDLEE-NPCEH-KVPSRNSHSDSSIYIRRHANRSLELDHFSYVQL
RNAADLDERRNRVLNR----------------------------------TGTNSSGEAV
PLGSQSPPNDSLTQFVQ--------------------QPDVVY----FILFLWLLVYCLL
LFPQLDVSRL---------------

------------------------------------------------------------
-VERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLGKCKPPLKVKDLFIDIQDGKILMALLEVLSGQKLMHEYK
SSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLNRNSSSSSLSSGPSGPESDTS-PSTPSVE--RNMS--ITVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RALLIWVQRKT
RKYGVAVQDFTSSWRSGLAFLAVIKAIDCTLVDMKHALEKSARENLEDAFSIAQNKLGVP
RLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPDKELPIESTYVHIKDTPS--
EKEGKILILSENEENMYTVNHERSHPAPPKVHIHDIP---E-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

------------------------------------------------------------
-VERENV

PF00307 // ENSGT00900000140842_0_Domain_1 (68, 174)

QKRTFTRWINL-HLEKCNPPLEVKDLFIDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMRENLGEAFSIAHDALHIP
RQIKKKYIMVDTPDEQSIVTYVAQFLEHFPELEAEDFVDSDKEAPIESTFVRIKETPS--
EQESAIFLLTEDGERAYTINHEASHPPPSKVFVCDKP---ED-----AKEPWLGGVSSQE
LV-DSSSEFMNQIIEQVLQGIPGKL-NSTSEPAPESSILSSRKDSRRSNSLPIKKTVHF-
-EADTYKDASCSQDPFYSADLHFEGSPGESKESS-KQDERVLAADAAEQTPKREAP--EI
LEVASNEVPGD-MSSVDGEIS-H-PPTSWTSPSWNGASERA-SSPGDEGHLPSPPGENTV
-MASALEIKVK-LLTVEAMDKEDYFEAIPLKASKFNSDLIDFASTSQAFNEVPSPHEKKP
AE--EELSEDHPERLGKRRGKSAHKKTDSDEAPVKLDQPDPHKDP------------GDQ
DQGYSLAPEEALVDKKPE--VYEKAKRKSFRRRRRGEE----EGEAEC---------LRG
LGGELPSNP-PRSSVSLETLRSPSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGSEDLKNE-EMDL--EEPEAYLL-DLGAREDEP-----------E---EAEASQS
SFSFSGLG-EDLPQASIA---------EDASPASEPSPQPSP-ED---------------
--HQQREAKD--SVPV-QGHQSQESP-NSENL-ASPLEEKVMEE-SISSKKKEKRKHVDH
VESSIFVAPGTVRSSDDLEE-DTGDH-KVLSRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADVDDRRNRMLTRYNTQKLTELILQFYGIRADMKRE---WKHARMSMQKANHSGKAR
LREIHSSQSDSLTQLVQ--------------------QPDVMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
-------------------------------------------MA

PF00307 // ENSGT00900000140842_0_Domain_1 (106, 174)

LLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLNRNSPSSSLSPGSGGTDSDSSYPPTPTTE--RNVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSARENLEKAFRVAHEALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDFVDLDKEDPIESTFVRIKETPP--
EQESKVLLLTENGEQAYTVNHETSHPPPTKVFVCDQP---ES-----TRGFCRGGMSSRS
LSSESSTDFMQQFIDQVLQGSPGKL-SSTSEPAPESSILSTRKDGRRSNSLPIKKTVHF-
-EADTYKDASCSNDPLYGPDLSFEESPSATQEPP-KQDEQAPSIQVAQEK-KPTQEPSAV
PGAASTRVPGD-LPGADDHA-----QPSQHPSSCNGAVEGP-PGLREEGHSPPHPGENTI
-LASAQEVKVT-LLTVEAADKEDYFEGIPLKASKFNSDLVDFASTSQVFPEAPLPQEKTP
AEE--VAADTPAEKLGKKRGKSAHTGRESPEPQLKRDRQE-PPKG-----------SEQE
ARVSSLAPDEAPVDKKPE--VYEKAKRKSTRS-----LEEEEGEAEG-LP--------GV
-VEELPSNP-PSGSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGTEDLKSE-DVDL--EEPEG-YPHELD-----------------PRNREAASAQS
SCSLSTLV-GVLPSASTHA-SYVNGNAAGAMPAAEPSPLSPN-KD---------------
--HQPRETKE--SGPE-ESPQSQGSP-RPENT-ANPLEVKVQEE-PTSSKKKEKRKHVDP
DEGSLFIAPGTVRSSEDLEE-DAGDH-KVPSRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADLDDRRNRMLTRKAK-----------------------------------NSGEAM
SLGSQSPQSDSLTQFVQ--------------------QPDVMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
-------------------------------------------MA

PF00307 // ENSGT00900000140842_0_Domain_1 (106, 174)

LLEVLSGRNLLHEYK
SSSHRIFRLNNIAKVLNFLEDSNVKLVSIDAAEIVDGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSCSLSPGSAGTDSDSCYPPTPTAQ--GNAG--ITGKDQRRAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEESPRENLEKAFRIAREALHIP
RLLEPEDIMVDVPDEQSLVTYVAQFLERFPELEAEDFMEPDREVPIESTFVRIRETPP--
DQESKVFLLTQNGEQTYTVNHETSHPPPAKVFLGDRL-----------------------
VP-ESSADFEHRNMDQALQGSPGKT-RTTSESAPESSILPTRKDSRRSSLLPTKKTVHF-
-EDGTYKDTSSSQEPFYSPGFRFEESPRAARELL-RQGRRASVEEEIQERTPEEV-----
---ASSEVPGA-----DGTVS-H-AQPLQDSSPFNGALEGP-ASHGEGSPSLPALRLNTV
-LADSITIKVK-LQTAEPLQKEGCVEGVPSQAVKLLNSMVDFASTSQTFGEAPAGEKAAG
MEEEE--------------EEEVGSGNCAQEPSVKCDRHRPPTGS------------GRE
SPGYFVSPEETPADKKPETPVHEKAKKKSPRPHSEVEE------EADGPWG---------
LGEQLSSSC-LRGSISLETLGS---------PSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGSEDTRSV-DSEL--EGPKDCLP-GPDPGEGD-----------------AEGPWD
SGSFSDPG-QGLPSASDQV-PPSSGHTGVATPASGPAPPALP-ED---------------
--QQPREAKD--SDPV-GSHQSPEFP-DPEST-ANSLEEKVMEE-STSSKKKEKRKHVDH
VESTLHGAPGIVQSSDDLED-GVGDH-GIPSRTSHSDSSVYIRHRANRSVESDHISFAQL
RNATAVGYRRNRTS-----------------------------------ARKASSSGEAK
SLGNQSPPSDSLAQLVQ--------------------QPDLMY----FILFLWLLVYCLL
LFPQLDINRL---------------

--------------------MAA-QEWDWFQREELI----GK---ISD------IRVQNL
QXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLHEYK

PF00307 // ENSGT00900000140842_0_Domain_1 (121, 174)

SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--PSAA--VSVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

RAIRTLLAWVQRRT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALQDSMRENLEKAFSIAHDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFVDSNKEAPIESTFVRIKETPS--
EQESTVFFLTENGERAYTMNHETSHPPPSKVFVCDKS---ES-----MKESHLDGVSSHE
LS-DSSTEVIHQVIDQVLQGVSGKT-SSISEPSPEYSILSSRKDSRRSNSLPIKKTVHF-
-ESDTYKDASCSKDPFYSPDFGFEGSPRPTKELS-KQDEHDLAVTIAEEKPKEEA--LKI
LEVASDEALGD-VSVADGKIN-N-SQTSQSSPSWDGTLERA-ASQGEESHPLSPLGEDTV
-MAESLEIKVK-LLTVQVMDKEDYFECIPLKASKLSSDLVDFASTSQAFNELSSPPKKKP
AE--DEVVEEHAEKLGKRRSKSTHKNEEPDEPRVAAGSHGPSMGL------------EQE
DQGYSLALDDGPVDKKPE--VYEKAKRKSLRHPAGEEE----AEAES----------PQG
LGRELPSSP-PSSSVSLETLRSHSEEGLDFRPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGSEDLKNE-ELDF--EEPEGYLC-DRGPGEGE---------------EEAEASQS
SCSFSGPS-KNLPQATVHE-LYLDEGAEGAQPASEPAAPAAQ-ED---------------
--PQQREAED--SVPG-ESHQSQESP-RSENL-ANPLEEKVMEE-SISSKKKEKRKHVDH
VESSVFVTPGTVRSSDDLED-DTGDY-RVLSRTSHSDSSIYIRRHSNRSLXXDHFSYVHT
RNAADLDDRRNRML-----------------------------------TRKATHSGEAI
LREGGGLHSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDINRL---------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLERAFRIAHDILHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEDFVNPDKEAPIESTFVRIKESPS--
EQESRVLLLSENGERAYTINHESSHPPPAKVFVCDQP---ES-----TKGFCLGGMPSRD
LS-DSATEFMHQIIDQVLQESPGK----TNEPAPESSILSTRKDGRRSNSLPIKKSVHF-
-EADLHKDASCSKDPFYSSDFRFEGSPRAAKEVS-KPDSYVSVVEVAKEKK-TEQEARPA
QEAASDKGPR-DTVGVDGMPH-H-SQPPQDPTFCNGTVEGP-ASQGEKGPSSASPGDHTI
-LANSTELKVQ-LLTVEPMDKDDYFEGIPLKASKFNRDLADFASTSQAFSEEPSPREKTL
EEE--EGFENYAEKLGKKKSKSPHAETESPESQAEPDKHESPPKG-----------PEQE
DQDHPLPPEETPADKKPE--VFEKAKRKSTRH-----RSEEEGEAED-LS--------GV
-GGEMPSNP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYSEGGEDLKNE-DADL--GEPEEGYLQDSREEE-----------------EEAHSSQS
SCSFSLPVDNGHPSVSDQV-SQVDENSEGPTSASGTGSSPSP-ED---------------
--HQQRETKE--NGPV-ESQQPQEPP-NLELP-TKPIEEKLTEA-STSSKKKEKRKHVDQ
VESSLFIAPGTVRSSDDLEE-NPCEH-KIPSRNSHSDSSIYIRRHANRSLELDHFSYVQL
RNAADLDERRNRVLNR----------------------------------TGTNSSGEAV
PLGSQSPPNDSLTQFVQ--------------------QPDVIY----FILFLWLLVYCLL
LFPQLDVSRL---------------

--------------------MAA-HEWDW-FQREE---------LI---GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAMDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHESSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPIKKTVHF-
-ETDTYRDPSYSKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DIFLAEGTIN---NSQS---SSYNGALEST-ARHDEESHSLSPAGEDTV
-MADSFEIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLVDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRGKRSTKSAHKKKDSPEPHGKTDKHE-PHQD-----------SGEE
AEGCPSAPEETPVDKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EEPEG-CMPDLD-----------------SREEEAGGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPAPPAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAA-HEWDW-FQREE---------LI---GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPSLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFTHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPIKKTVHF-
-ETDTYKDPSCRKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DIFLAEGTIN---NSQS---SSYNGALEST-AHHDEESHSLSPPGENTV
-MADSFEIKLN-LMTVEALEEGDYFAAIPLKASKFNSDLVDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRGKRSTKSAHKKKDSPEPEVKTDKHE-PHQD-----------SGEE
AEGCPSAPEETPTDKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETFGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EEPEG-YMPDLD-----------------SREEEADGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPAPPAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIESSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYIQL
RNAADLDDRRNRMLTRKAS-----------------------------------SSGGTM
SPGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
--EREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXX--XXXXXXX

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

XXXXXXXXXXXXXX
XXYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPEVEAEDFVDLDKEIPIESTFVHIKETPS--
EQESKILLLTENGERAYTINHESSHPPPSKVFVCDKPDKPES-----GKGFSLGGVSSRA
LS-DSSTEFMHQIIDQVLQATPGKT-SGVSDPSPESSILSSRKDNRRTNSLPIKKTVHF-
-EADIYKDASCSRGPFHSHDVGFEGSPGTAKGPL-TQDGHVLAAEVE-EK-TQKQEASTI
REAASDGVPSDVLG-DS--------------SSPRGPSAGN-GAGGRESPAPPTPGXXXX
-XXXXXXXQVQ-LLTAEAMDED-DFEGVPLKASKFNSDLVDFASTSQAFHEVPSPPEDKP
AEG--EVSEHCAEKLGKRRVKSAHKKKDSSEPRDQADPQE-PQEG-----------SPQE
AQGYAG----APADGKPE--VYEKAKRKSSHR-----PGEEEGAAEG-LQ--------GL
-GGELPSNP-PSSSVSLETLGCHSEEALDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGTEELKNK-DVDL--QEPEG-YSHDLD-----------------SQEEQAGGSQS
SSSFSVPG-VRSPSARDQE-SDLGRDTEPAIPASEPTASPPE-ED---------------
--QHQREAGE--SDPG-EGQKSQESP-NLETV-ANPLEEKVTGG-SVSSKKKEKRKHVDH
AESSLFVAPGTVHSSDDLED-NAGDH-QVPSRPSHSDSSIYIRRRSNRSLESDHFSYIQL
KTAADLDDRRNRTSTRKAS-----------------------------------NSGEAG
LPGPCGLQSDSLTQLVQ--------------------QPDMMY----FIIFLWLLVYCLL
LFPQLDITRL---------------

--------------------MAA-QEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSVA--VAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLSWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRDNLEKAFSIAHDSLHIP
RLLEPEDIMVDMPDEQSIVTYVAQFLERFPELDPEDFVNPDKEAPIESTFVRIKESPS--
EQESRVLLLSENGERAYTVNHETSYPPPDKVFVCDQL---ES-----PTGFCLDSAPSHK
LS-DSSTEFMHEIIDQVLQGSSGKTG-SITEPTPESSILSTRKDGRRSNSLPVKKTVHF-
-EADLHKDASCSKDPFYSSDFRFEGSPKATKELS-KQDGHVSLAEVSKEK-KSEQEARLV
LEAASDKVSESMVDGLDAVPQ-D-AQPSPDSSFCNGTVESP-SSQGEKGPPPPPPGDHTL
-LANSTELKVQ-LLTVEPMDKEDYFECIPLKASKFNRDLVDFASTSQAFGEDPSSHEKTR
GEE--EGSENHAEKPGKRKSKSPRAETESAESRLEPKKLRPPPKD-----------PEQE
DQGHTLPPE-APADKKPE--VYEKAKRKSTRH-----HSEEEGEAESGLS--------AV
CE-EIPSTP-PSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEDLKSE-DTDL--EHPEDSYLQDSREEEAD------------EDEEEAQSSQS
SCSFSLPVDNSYPSVSEHV-SHVDGSSEGPTSALGPGSPPSH-ED---------------
--HQPKETKE--NGPV-ESQQSQEPP-NPELP-TKPLEEKLTEA-STSSKKKEKRKHMDH
VESSLFIAPGMVRSSDDLEE-NSSEH-KVPSRNSHSDSSIYIRRHTNRSLELDHFSYVQL
RNAADLDDRRNRVLNRYNSQKLTELILQFYGIRADMKRE---YKHARLSMTGTNSSGEAV
PLGNQSPPNDSLTQFVQ--------------------QPDVIY----FILFLWLLVYCLL
LFPQLDVSRL---------------

--------------------MAA-HEWDW-FQREE---------LI---GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDVFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHESSHPPPSKVFVCDKP---ES-----MKEFRLDGISSRA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPIKKTVHF-
-ETDTYRDPSCSKNL----SLCFEGSPRAAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DLFLAEGTIN---NSQS---SSYNGALEST-ARHDEESHSLSPPGEDTV
-MADSFEIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLVDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRGKRITKSAHKKKDSPEPQGKTDKHE-PHQD-----------SGEE
AEGCPSAPEETPADKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EEPEG-CMPDLD-----------------PREEEAGGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPTPPAPH-EE---------------
--HQQRETKE--NDPV-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
-------------------------------------------MA

PF00307 // ENSGT00900000140842_0_Domain_1 (106, 174)

LLEVLSGQNLLHEYK
PSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSMVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLNRNSSSSSLSSGPSGPDSDTSHPNTPNVE--KNMS--VGVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

KAILTWVQRKT
RKYGVAVQDFASSWRSGLAFLAVIKAIDPNLVDMKQALEKTSLENLEDAFTIAQDYLGIP
RLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEREDFSDPDKEFPVESTYVHVKESPG-D
EIQGKVLILNENGEHTYTPVLNRSHSPPPKIHILSLP---LDQENQERNDN-----QDHS
LS-N--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

--------------------MAA-PEWDWFQREELI----GQ---ISD------IRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWVNL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSTA--IAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAQEALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFMDSDREAPIESTFVRIRETSS--
EQESALFLLTENEERAYTVNHEASHPPPSKVFVCDKP---ED-----VVERCLGGVSSQE
PP-DGSSESTHPIIEQVLQGVPRKI-STPSEPAPESSILSSRKDTRRANSLPGKKTVHF-
-EADTYRDAACSQDPFYSQDPRFEGSPRGSKEGS-KQDGHVSAGEVAGESPKQEAPRVPA
AA--PAEAPGE-VSLVDGKIE-H-PPPFQPSPSWNGASEQA-ASPGEEGHPLSPLGGVPV
-MANSLEIKVK-LLTVKAMEREDYFEGIPLKASRFNSDLIEFASTSQAFNEAPSAHEK-T
PAEKEQVPEDPAENLGKRRDSSGHQQTDGDESPGNPDPHAPPQDA---------G-PE--
EPGYSLAPQGTPVDKKPE--VYEKAKRKSPRRRR-GED----GEAGDPPG----------
LGREWPSTL-ASSSASLETLHSASEEDLDFKPSPPLSKIS-VPPDLFYYPHYEVPLAAVL
EAYAEGPEDLKSQ-EMDL--EEPEGYPP-GLGAREDEDED------------EEAEPSQS
SCSFP-GL-GEDR----PQ-ASIA---EDARRASVPTPPARR-ED---------------
--DQPREPAE--NVPV-PDQQSQEFA-NSENL-ANPLEEKVKEE-SISSKKKEKRKHVDH
VESSVFIAPGTVRSSDDLEE-DISDH-RVISRTSHSDSSIYIRRHTNRSLESDQVSYVQL
RNAADLDDRRNRTL-----------------------------------TRKANNSGEAG
LQEGRGPQSDSLAQLVQ--------------------QPDVMY----FLLFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAA-QEWDWFQREELI----GQ---ISD------IRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALTFLEESNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTAE--RNAA--IAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVVKAIDPSLVDMKQALEESPRENLERAFQVAHDALHIP
RLLEPEDIMVDVPDEQSVVTYVAQFLERFPELEAEDFVDPDKEVPIESTFVRIRETPS--
EQESKVFLLTQNGERTYTVNHEASHPPPAKVFVCDRP---EG-----SQGPCPDSMPSST
LS-DSSAEFVHQIIDQVLQGGPGTT-SSTSEPASEFFMLTTRRDSRRPSLPPTKKTVHF-
-EDVTDKDTSGRQEPFHSPAFHFEGSPRPARELL-RQGGRASVEDDAEEGEPEEA-ASPI
PEPASSEVPGA-----RGAAS-H-AQPPEDSSSFSGALEGP-GGCGAERPSVLPLGISTV
-LASTTEVKVK-LQTAEPLGTKGCPEGAPSRAVTVTGDMVDFASTSQGLSELPPPGKKTA
GAEKAAAASEN----------C------AQESQVGCDRHGPPAGA------------TQE
PPSYSSSPKEIPRDRKPETPVHEKAKRKSPRRHSE--E----EEEADSPLGLGEES----
--EELSSSS-LRASISLETLTSHSQEGLDFKPSPPLSKISVIPHDLFYFPHYEVPLSAVL
EAYAEGTEDGRDR-----------DYLP-DLDPGEQD-----------------TEGSWS
SCSISAPG-KGLSSASSQV-LPPSGHTTEATLASGAAPPGLY-ED---------------
--PQPRESRD--SEAM-ESHQPQEFP-DPESI-ANSLEEKVMEE-STSSKKKEKRKHVDH
VESSLYRAPVMVQSSDELED-DFGDY-RVPSRTSHSDSSIYIRRHANRSLESDHISFVQL
RNAADLDDRRNRMLTRYNTQKLIELILQFYGIRADMKRE---CKHAGM-SMKPSSSGEAE
SLGPQSPQSDSLTQLVQ--------------------QPDMMY----FLLFLWLLVYCLL
LFPQLDITRL---------------

---------------------------------------------------------LIF
VVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLGKCKPPLKVRDLFMDIQDGKILMALLEVLSGQKLMHEYK
SSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLNRNSSSSSLSSGPSGPESDTSYPSTPNIE--RSMS--VTVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIRALLFWVQRKT
RKYGVAVQDFASSWRSGLAFLAIIKAIDSTLVDMKHALGKPARENLEDAFSIAQNKLGVP
RLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPEKELPIESTYVHIKDTPS--
EKESKILILRESDKNMYTVNHERSHPAPPKVHIHDTP---E-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------IKELTG
NLSRSSPSSSLSPGSGGTDSDSSYPPTPTTE--RSVA--VSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSMQENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEPEDFMNPDKEAPIESTFVRIKESPS--
EQESRVLLLTKNGERAY-VNHKTSHPPPAKVFVCDQP---ES-----TKDFYLGAVPSHR
LS-DSSTEFMHQIIDQVLQGSQEKTEATTSEPDPESSILSTRKDGWRSSSLPVKKTVHF-
-EADLHKGVSCSKDPVYSPDLCFEGSPGAAKELS-KQDGHVLLTEAAEEK-KLEQEAKPV
LEVASDKASE-DTVHVDGMPH-H-AQPLQDSSFCNGTVESL-ASHAEEGPPPS-LEDQAV
-LANSTELKVP-LLTVEPMDKDDYFEGIPLKASKFNRDLADFASTSQALSEVPSLHEKPS
G-E--EGFEGYPEKPGKRKSKSPHTKRESPESQAEPD--KPPPES-----------PEQE
GQDHPLPPEEAPVDNKPE--VFEKAKRKSARH-----HSEEEGEAEG-LP--------GV
-GGEIPSNP-PSTSVSLETLRSHS---LDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGGEGLKSE-DVDL--EEPEE------------------------EEEEEAHSSQS
NCSFSVPSVEVHPCTSDQV-PPVNGGGVEATPDSGPASPPHHDED---------------
--HQPRETRE--SDPV-ESQQSEDSQ-KPEQP-RKPLEETVVEE-STSSKKKEKRKHVDQ
VESSLFIGPGTVRSSDDLEDSSPCEH-KVPSRTSHSDSSIYIRRHTNRSLELDHFSYVQS
RNAANLDDRRNRMLNRYNTQKLTELILQFYGIRADLKRD---YKHARM--NGTNFSGEAV
PPGSRSPPSDSLTQLVQ--------------------PPDVMY----FILFLWLLVYCLL
LFPQLDVNRF---------------

---------------------------MVVQSRTQ-------------HAGSSSPGAGPA
AVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
CSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTERERSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKILVLNENGEHTYTFNYETSHPPPSKVFVCDKP---ES-----MKEFRLDGISSHA
LS-DSPTEFVHQIIDQVLQGGPGDT-SDISEPSPETSILSSRKESPRSNSLPIKKTVHF-
-EADSCKDASCSKDL----SLHFEGSPRVAEEPL-MEDGHVLAVEVAEEK-EWKQESLKI
PESFSDKVPG-DVFLAEGAIS---NSQSS--STYNGALEST-ASHDEESQSLSPPGENTV
-MANSVEFKVN-LMTVEPLDEGDYFEAIPLKASKFNSDLIDFASTSQAFNEVPSLHETKP
DED-DEALENHAEKLGKRSTKSAHKEKDSPEPQVKSNKHG-AHQD-----------S-RE
AEGCPSAPEETPTDKKPE--VYEKAKGKSIRP-----YDEEEGEDDD-LQ--------GV
-CEELSSSP-TSSNVSLETLRSHSEEGLDFKPFPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--KGPEG-CMQDLD-----------------SREEEADGSQS
SCSSSAPG-EYLPSASDPV-LYLNGDGGSTTPASEPAPLAPH-ED---------------
--HQQRETKE--SDPV-DSHQSQESP-NPENI-ANPLEEKVTKE-SISSKKKEKRKHVDH
VESSLFIAPGTVRASDDLED-DIGDH-SVPSRTSHSDSSIYIRRHSNRSLESDHFSHVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------LAK-RLWSWAGKKWIL----A----TM----QVIVDPLLF
SVERENVQK

PF00307 // ENSGT00900000140842_0_Domain_1 (70, 173)

RTFTRWVNL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILF

ENSGT00900000140842_0_Linker_1_2 (173, 230)

FQIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSMA--VSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 329)

RTLLAWVQRKT
RKYGVAVQDFAGSWRSGMAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAHEALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEAEDFSDLDKEAPIESTFVRIKETPS--
EQESTVFLLTENGDRAYTINHEASQPPPSKVFVCDKP---ES-----MKESFQDGVSSCA
LS-DSAPEFMHQIIDQALQGDPGKA-SSTNDPSPESSILSSRKDSRRSNSLPIKKTVHF-
-EADTFKDASYSKDPFYSHDFRFEGSPRGTKDSL-KQDGYLLAVEIAEEKSQQEAP--KI
AEAASDESPGD-VSLADGKSN-H-SQTSQSSPSWNGEPEGA-GSPGEESCPLSPLEDNTI
-MANSLEFKVK-LLTVEAMGGEDYFEGIPFKTSKFSSDLIDVASTSQAFNEVPSPHEKKP
AE--DEVLEDHAEKPEKRRSKSVHQRKDSDESPERPDGLEPHRDT------------GQE
DQGSSPAPGEAPVDKKPE--VYEKPKRKSPRRRRGEDN----GEAPGL----------QE
PEGELSPDP-LRGSDSLETLCSRSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVL
EAYAEGVEDLKNE-DLEL--EEPEGYPC-AVGARDEAQEA------------AEAEASRS
SCSFSGPE-EDVPEASIPAAPCPDGGVEDATLAAEPATLSPP-DD---------------
--RQRGEADD--CAPV-ESHQAQEFG-NSGTL-ANSLEEKVMGE-SISSKKKEKRKHVDH
VESSVFIAPGTVRSSDDLEE-DTGDH-KVLSRTSHSDSSIYVRRHTNRSLESDHFSYVQL
RNAADLDDRRNRMLTR-----------------------------------KANNSGEAT
LPESQSPQSDSLTQFVQ--------------------QPDLMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAT-LEWDWFQREELI-------------GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_0 (67, 113)

VQKRTFTRWINL-HLEKCDPPLEVTDLFVDIQDGKILMALLEVLSGRNLVCMP-
---HTLWCLCPLCRGTSSLWQH--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

------------------------------------------------------------
-------------------------------------------MALLEVLSGQNLLHEYK
SSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFFQIKELTG
NLNRNSSSSSLSSGPSGADSDTSHPSTPNIE--RGMS--VSVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

RVLLTWVQRKT
RKYGVAVQDFTSSWRSGLPFLAIIKAIDSSLVDMKQALEKSARENLEDAFSIAQNSLGVP
RLLEPEDIMVESPDEQSIVTYVAQFVEHFQELEGEDFSDPDKEIPIETTYVHIKDTPS--
EQESKILILNENGECAYTVNHERSHSPPTKVCVHDLP---EELQSENVHEELTDKLNQ--
----------------PL------S-ANSQEVSEESLVLSSVEEHQRPTSLQITGSVSF-
-ESSSSWEVLSDKLIQNEGSI--S------DDQL-KENDELSATILTEQKNSVDTV----
----------------DSESSSKEELTIKTSPECNNEIKD--------------------
----SLVNK--------------TCDSYPLRPLSQISDIHEKEPTNLVENTEPII-----
-----------------------------------------------STFLPEYASKEED
MPKYILHLLNEEISKKLS-EGYEHPKQPPVFHTLQDTN--WSSKDSDLKG-QMEM--SLS
CKSENST---SPVTKKSENLEMHNEDESSAKMSPNSSKVSVIPHDLFYYPHYTVPISAVL
EAFAEPRPASYISENSKICDELSVNYFH-EGEPLVL--------------------NSEG
GI--LELG-LQ---TSLSV--SPAQMEAEATEEEKVDPDSPT-KS-----FSEKVQD-VL
IEEN-VELKED-ISIC-TNSQDSTNPENPEIVWLEDTLSAVQRP-KISSKKKEKKKNVIQ
AENFQTSEIETTQLPDKQKQ-EIVHY-QEFSRLSYSDSSVYLKNRIPNSTEKEHVSDNKQ
KNT-DMGESTNLLIIRKK---------------KDL------------------------
-EAPENAIPPPEPPCVE--------------------QPELFY----FIVFLWVLVYCLL
LLPHLVSNKL---------------

------------------------------------------------------------
--EREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLGKCKPPLKVKDLFMDIQDGKILMALLEVLSGQKLMHEYK
SSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLNRNSSSSSLSSGPSGPESDTSHPSTPNVE--RNMS--VTVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 326)

KAIRALLIWVQRKT
RKYGVAVQDFASSWRSGLAFLAVIKAIDSTLVDMKQALEKSARENLEDAFSIAQNKLGVP
RLLEPEDIMVESPDEHSIVTYVAQFL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

--------------------IAA-HEWDWFQREGFI-------------WQLSDIRVQNL
QXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLHEYK

PF00307 // ENSGT00900000140842_0_Domain_1 (121, 174)

SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXX--XXXXXXXXXXXXX

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 319)

XXXXXLLAWVQR-T
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDALHIP
RLLEPEXXXXXXXXXXXXXXXXXXXXXXXXXXXXDDFVESDREFPIESTFVRIKETPS--
EEESKVFFVTENGERAYTINHETSHPPPAKVFVCDRP---ESVG-ALPLQPCLEDAISGG
PP-DSPGDLMEQIIDQVLQDIPYKA-GDVSELSPETSILSSRKDSRRANSLPTKKTVHF-
-EADTYKDASCSKDPACSQGVCFEGNPRGAKESL-NQDGHTSAIEDDEGKKPKQ-EAPKT
LEAASDKALDG-ALSADGKAS--DSQSSQGSPAWSGAPGRT-ADHEGESHSLASAGENTP
QMADSXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX---XXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------XXX
XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXX----XXXXXXXXXX------XX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXRND-SADL--RRPDNYRQ-DLDSME-------------------EVDCHS
GCSFSVTG-KDLPKASDQV-PYLDREAVGTQPAPDPVFPAHL-ED---------------
--HHQGETKE--SNPSETGQXXXXXX-XXXXXXXXXXXXXXXXX----XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXTSHSDSSIYVHRHTNRSLES--------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

-------------------------------MAAHEWDWFQREEL---IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHETSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKENGRSNSLPIKKTVHF-
-EADTYKDPFCSKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAEEK-EQKQESSKI
PESSSDKVPG-DIFLVEGTNN---NSQS---SSCNGALEST-ACHDEESHSLSPPGENTV
-MADSFQIKVN-LMTVEALEEGDYFEAIPLKASKFNSDVIDFASTSQAFNKVPSPHETKP
DED-AEAFENHAEKLGKRSIKSAHKKKDSPEPQVKMDKHE-PHQD-----------SGEE
AEGCPSAPEETPVDKKPE--VHEKAKRKSTRP-----HYEEEGEDDD-LQ--------GV
-GEELSSSP-PSSCVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYVEDPEDLKNE-EMDL--EEPEG-YMPDLD-----------------SREEEADGSQS
SSSSSMPG-ESLPSASDQV-LYLSRGGVGTTPASEPAPLAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQECP-NLENI-ANPLEENVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSVQSSDDLEE-DSSDY-SIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRILTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVSRL---------------

--------------------MAA-HEWDW-FQREE---------LI---GQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDVFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHESSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSRA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPIKKTVHF-
-ETDTYRDPSCSKNL----SLCFEGSPRAAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DLFLAEGTIN---NSQS---SSYNGALEST-ARHDEESHSLSPPGEDTV
-MADSFEIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLVDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRGKRITKSAHKKKDSPEPQGKTDKHE-PHQD-----------SGEE
AEGCPSAPEETPADKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EEPEG-CMPDLD-----------------PREEEAGGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPTPPAPH-EE---------------
--HQQRETKE--NDPM-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------MRNSSSLVLPREPIIIS-RIWQL-LHKYQISPWEGEGVILRVFLFLPANGVSLF
SVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDVFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHESSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSRA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPIKKTVHF-
-ETDTYRDPSCSKNL----SLCFEGSPRAAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DLFLAEGTIN---NSQS---SSYNGALEST-ARHDEESHSLSPPGEDTV
-MADSFEIKVN-LMTVEALEEGDYFEAIPLKASKFNSDLVDFASTSQAFNEVPSPHETKP
DED-AEAFENHAEKRGKRSTKSAHKKKDSPEPQGKTDKHE-PHQD-----------SGEE
AEGCPSAPEETPADKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDL--EEPEG-CMPDLD-----------------PREEEAGGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPTPPAPH-EE---------------
--HQQRETKE--NDPM-DSHQSQESP-NPENI-ANPLEGNVTKE-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

------------------------------------------------------------
-----------------------CDPP

PF00307 // ENSGT00900000140842_0_Domain_1 (88, 174)

LEVTDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALTFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSYPPTPTAE--SNVA--IAVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KTLLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEESPRENLERAFQVAQETLHIP
RLLEPEDIMVDVPDEQSIVTYVAQFLERFPELEAEDFVDPDKEVPIESTFVRIRETPP--
EQESKVLLLMQNGERTYTVNHETSHPPPTKVFLCDRP---GG-------------TASSV
LS-DSSTEFVHQIIDQVLQEGLGT----SSEPAPESSNLCPRRNSQRPSFLPTKKTVHF-
-EDGAYKEPSGSQEPFYSPHFVFEGSPRPSRELL-QQGRWALLEAEAEERKLEE-AASPI
PGAGSSEVPGA-----HGPVS-P-TQPPPDSFSLNGTYEDLAGHLGEENPSLQPLGVNTV
-LASSMEIKVK-LQTAEPMGTEDYLEGVPSQAGRFVSDSVDFASTSQGSGETSPGEKATG
----------------KEEAVEAASGNSAQEPQGGCDRHEHPTDS------------GQK
SPSHSSSPKETPVDRKPETPVYEKAKRKSPRHRSEDEE------DARGPPG---------
LGKELFSSS-LRASISLETVGSPSEEGLDFKSSPPLSKVSVIPHDLFYYPHYEVPLAAVL
EAYAEGTEDVNDK-----------DCLP-DMDPGEGN-----------------TEGSWS
SCSFSTLG-EGLPTASSQA-LPPTSHATAVTPASEAAAPALC-ED---------------
--QHESHQIE----LL-LGPFQQEFP-DSENI-ANCLEEKVMQESSTSSKKKEKRKHVDR
VDTSSYTAPGIVQSSDDLED-DLGDC-RVPSRTSHSDSSIYIRRHTNRSLELDHISFVQL
RNAADLDDRRNRMLTRYNTQKLIELILQFYGIRADKKRE---CKHAGM-SMKPSSSGEAE
SLGTQSLQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDIIRL---------------

------------------------------------------------------------
--EREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAE--RSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKVFVLTENGERTYTVNHESSHPPPSKVFVCDKP---ES-----MKEFRLDGVSSHA
LS-DSSTEFMHQIIDQVLQGGPGKT-SDISEPSPESSILSSRKESGRSNSLPIKKTVHF-
-ETDTYRDPSFSKNL----SLCFEGSPRVAKESL-RQDGHVLAVEVAAEK-EQKQESLKI
PESSSDKVPG-DIFLAEGTIN---NSQS---SPYNGALEST-ARHDEESHSLSPPGEDTV
-MADSFEIKVN-LMTVEALEEGDYFEAIPLKTSKFNSDLVDFASTSQAFNKVPSPHETKP
DED-AEAFENHAEKRGKRSTKSAHKKKDSPEPQGKTDKHE-PHQD-----------SGEE
AEGCPSAPEETLADKKPE--VHEKAKRKSTRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-PSSRVSLETLGSHSEEGLDFKPSPPLSKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDLKNE-EMDF--EEPEG-CMPDLD-----------------SREEEAGGSQS
SSSSSVPG-ESLPSASDQV-LCLSRGGAGTTPASEPAPPAPH-ED---------------
--HQQRETKE--NDPM-DSHQSQESP-NPENI-ANPLEGNVTKD-SISSKKKEKRKHVDH
VESSLFVAPGSIQSSDDLEE-DTSDH-CIPSRTSHSDSSIYIRRHTNRSSESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQLVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

--------------------MAA-HEWDWFQREEL-------------IGQISDIRVQNL
QVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWINL-HLEKRNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
CSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 230)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERERSVA--ISVKDQRKAI

PF00307 // ENSGT00900000140842_0_Domain_2 (230, 330)

KALLAWVQRKT
RKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIP
RLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPS--
EQESKILVLNENGEHTYTINHETSHPPPSKVFVCDKP---ES-----MKEFCLDGISSHA
LS-DSSTEFVHQIIDQVLQGGPGNT-SDISELSPETSILSSRKESQRSNSLPIKKTVHF-
-EADTGKDASCSKDL----SLHFEGSPRVAKEPL-MEDGHVLAVEVAEEK-EWKQESLKI
PESFSDKVPG-DVFFVEGTIN---NSQSS--SSYNGTLEST-ASHDEESHSLSPPGENTV
-MANSVEIKVN-LMTVEPLDEGDYFEAIPLKASKFNSNLIDFASTSQAFNKVPSPHETKP
DED-DEAFENYAEKLGKKSTKSAHEEKDSPEPQVKSDKHE-AHQD-----------SGEE
AEGCPLAPEETPTDKKPE--VYEKAKGKSIRP-----HDEEEGEDDD-LQ--------GV
-GEELSSSP-SSSSVSLETLGSHSEEGLDFKPSPPISKVSVIPHDLFYFPHYEVPLAAVL
EAYAEDPEDVKNE-EMDL--EGPEG-CMQDLD-----------------SREEEADGSQS
SCSSSAPG-ECLPSASDQV-LYSNRDGGSTTPASEPAPLAPH-ED---------------
--HQQRETKE--SDPM-DSHQSQEFP-NPESI-ANPLEEKVTKE-SIGSKKKEKRKHVDH
VESSLFIAPGTVQSSYDLEE-DTGDH-RVPSRTSHSDSSIYIRQHTDRSLESDHFSYVQL
RNAADLDDRRNRMLTRKAN-----------------------------------SSGEAM
SLGSHSPQSDSLTQFVQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVNRL---------------

---------------------------TLRGPSWEE----E----SSILHVHPANGISLF
SVEREN

PF00307 // ENSGT00900000140842_0_Domain_1 (67, 174)

VQKRTFTRWVNL-HLEKCDPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYK
SSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFF

ENSGT00900000140842_0_Linker_1_2 (174, 227)

QIKELTG
NLSRNSPSSSLSPGSGGTDSDSSFPPTPTTE--RSLA--VSVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIRTLLAWVQRKT
RKYGVAVQDFTGSWRSGMAFLAVIKAIDPSLVDMKQALEDSMRENLEKAFSIAHEALHIP
RLLEPEDIMVDTPDEQSIVTYVAQFLEHFPELEADDFVDSDKEAPIESTFVRIKETPS--
EQESTVFLLTENGERAYTINHEASQPPPSKVFVCDKP---ES-----GKECFLSGVSSSA
LS-DGSAEFMHQIIDQALQGVPGKA-SNTNDPSPESSILSSRKDSRRSNTLPVKKTVHF-
-EADTYKDASCSKDPFYSQDLRFEGSPKGTKDSLLKQDGYILAVETAEEKLKQEAP--KI
SEAASDESPGD-ISLVDGKIS-H-SQTTQNSPSWNGEPEGA-ASPGEVSRPLSLLGDDTV
-MADSLEIKVK-LLTVEAMGKEDYFEGIPLKASKFSSDLIDFASTSQAFKGVPSPHEKKP
VE--GEVSEDQPEKLGKRRSKSAHQRKDSDESPERPDKLEPHRDP------------RQE
DQGYSLAPGEAPVGKKPE--VYEKPKRKSTRRRRGKDE----GEAAGPQG-LGP----QG
PERELPSEPPPSSSVSLETLPSHHEEGLYFKASPPLSKVSVIPHDLFYYPHYEVPLATVL
EAYAEGAEDLKNE-DLDL--EELESYLC-DVGVGDEAEEA------------EEAEASRS
SCSFSGLA-EDVPKASIPVVPCPDRGVEDARPASEPTDPSPP-ED---------------
--RQRGGAED--RSPV-ESQQSQELG-NSENL-ANSLEEKVMGE-SISSKKKEKRKHVDH
VESSIFIAPGTVQSSDDLED-DTGDR-KVLSRTSHSDSSIYIRRHTNRSLESDHFSYVQL
RNAADLDDRRNRTLTRYNPQKLTELILQFYGIRADMKRE---CKHARMSIRKANNSGEAT
LPESQSPESDALTQFAQ--------------------QPDMMY----FILFLWLLVYCLL
LFPQLDVHRL---------------

------------------------------------------------------------
--ERENVQKRTFTRWINL-HLEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXVKLVSIDAAEIADGNSSLVLGLIWNIILFFQIKELTG
NLNRNSSSSSLSSGTPGPDSDSSLPMTPKGE--NSVA--LSVKDQR

PF00307 // ENSGT00900000140842_0_Domain_2 (227, 330)

KAIRTLLNWVQRRT
RKYGVAVQDFAGSWRSGVAFLAIIKAIDPNLVDIKQALEDSARENLEKAFSIAHDKLHIP
RLLEPEDIMVDSPDEQSIVTYVAQFLEHFPDLEGEDFTDPDKEIPIESTFVRIKETPT--
EQESKIFLVPEKGERTYTVNCETSQPPPPKVFVCDKW---KS------TNECLSESSSHK
GP-GSPKNQPSHITEQAFPGGLTKP-SDISESLSEQSILLPKKAGHRPDTLPIKKTVHF-
-ESDISKDASCSKDF-VKGNLGKINEP------L-KQDNSVSSSSVSNKMKAKE-GCMKT
LGSALNKILDD-YPLTHKKNSGF-----SASEVLPGYSEE------------EANKGHDI
-NPHSLEVRGQ-KLIQETIDEIAKFEERTMESLKQGTEMKGLTGLGQTLHDKNSSPGEKN
ASH-SIVSEANMEQLAR-KHKCRRKMKDSXXXXXXXXXXXXXXXXXXXXXXXXXX-----
X-X---XXXXXX-XXXXX--XXXXXXXXXX-XXXXXXX----X-XXXXXX----------
XXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX-XXXX----XXXXXX-XXXXXXXX-----------------XXXXXX
XXXXXXXX-XXXXXXXXXX--XXX---XXXXXXXXXXXXXXX-XX-----------X-XX
XXXXXXXXXX--XXXXXXXXXSQDFQ-NVG---KLCLFGELPEE-ASSLKKKKEWHHGDQ
TESSLFVAAKAAHFSEDLEE-EXXXXXXXXXXTSHSDSSLYNRRQGNKSSEMXXXXXXXX
XXXXXXXX-----------------------------------XXXXXXXXKVSSFGEAM
LQGHHGAHSDSLVHFAQ--------------------QQDLVY----FILFLWLLVYCLL
LFPQLDIKKL---------------