ENSGT00900000140828_1 : Linker Region Query Results

-------MEVKP-PP----GSPQPD--------SSRRKEGHDPKEPEQLSKLFIG-DL--
--------------KHFEEWGTLTDCVVMR--DPQT---KHSRGFGFVTYSC---VEEVD
AAMRARPHKVDG RVVEPKR-AVSREDS-VKSGAHLTVKKS--------------------
F------IETLEVMEDWQSGKK---RGFAF-VTFDD-HGTVDKIVLQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSGH----GGGNF-MGR-GGN------FGGG---GNFGG---
-R-----GGYGGGG--------GGSRGS-YGGGD-GGY--NGFGG-DGGNYGGGPGYS-S
RG-YGAGG-T-G--Y---------GNQGGGYGG-----GGGGYDGYNEGGNFGAG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------------------------MEVKPPPLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDYVVMR--DPQT---KRSRGFGFVTYSS---VEEVD
AAMC ARPHKVDGHVVEPKR-AVSREDS-VKPGAHLTVKKI--------------------
FY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDIVDKIV---------------
-------ALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGI------LGGG---GGNFG---
-R-----GGYGGGG--------GGSRGS-YGGGD-GGY--NGFEG-DGGNYGGGPGYR-S
RGGYGGGG-P-G--Y---------GNQAGGNGG-----GGGGYDGYNEGGNFGGC----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------GHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQVRKLFIG-GLSF
ETTD--DRLR----EHFEKWGTLADCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVTEDRQSGKK---RGFAF-VIFDD-HDT---------KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-G---------------GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGSGPGYS--
-SR--GGYGGGGPGY---------GNRGGGYGG----GG-GGYDG-----NFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPRPSRSQPDSGSRC--------HCRGEEGNDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHSEKWGILTDCVVMR--DPQT---KRSRGFGFVTFSC---AEEVD
AA MCARPHKVDARVVELKR-TVSREDS-VKPGAPVTVKKFFF GGIKEDTE-EYNLRDYFE
KY---GKIKTIEVMEDRQSGKK---KGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCDVKKALSKQEMQS-AGSQRGRGSGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--KGGYGGEG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGSGYS-S
RGGYGGLVVA-G--Y--------G-NQGGGYGGG---GG-GGYDGYNKGGNFGGG----N
YVGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRRRRRRG--------EEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
XX---XXXXXXXXXXXXXXXXX--XXXXXX-XXXXX-XXXXXXXX-Q--KYH----TING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGG-GGG--------SRGS--YGGGDGGY--NGFGG-EXXXXXXXX-----
XXXXXXXXXX----X---------XXXXXXXXXX----XXXXXXXXXXXXXXXXXX----
XNLGANYNDFANYSQQQ-SIYGPMTG--GFGGRSSG----SPYGGGYGSGG---------
GS-GGYGSRR-F------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP--GGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPSRTQPDSGGRR--------------------RQQLRKLCIG-GLSF
ETAD--DSL----REHLEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRNYFE
KY---GKIETIEVMEDRQGGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----INR
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYDGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGEYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPNEPEQLRKLFIG-GLSF
ETTD--DSF----REHFEKWGTLTDCVVMR--DPQT---KHSRGFGSVTCSC---VEEVD
AAMCAQPHKVDGRVVKPKR-AVSREDS-VKPGAHLTVKNIFVGGVKEDTE-EYNLRE---
--------------LLRKGGKK---RGFAF-ATFDD-HDTVDKIVVQGRKYHT----ING
QNCEVQKALSKQEMQSA-GSQGGRGGGSG-------------------------------
--------GYGGGG--------GGSRGS--YGGGDGRY--NGSGG-DGGNYGGGPGYS-S
RGGYGH-DGP-G--C--------G-NQGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSLG----IPYGGGYGSG----------
GGSGGYGSSRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGNRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYNGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------VAVKPPPGRPQPDSGRR------------HCEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEQVD
AAMC ARPHKVDGRVVEPKRRAVSSEDS-VKPGAHLTVKK IFIGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-GTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------SGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGD--SGNYGGGPGYS-S
RGGHGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGAPHPTRR-----Q--------GKEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMT--DSQT---KRSRGFRFVTYSC---VKEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKNIFVG-------------DYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFND-HDTADKIVVQ--KYH----TING
HNCDVKKALSKQEMQSA-GSQRGRGGGSGNF-MGH-GGN------FGSG---GGNFGCGG
NFGG--RGGYGGGGGG--------RRCS--YGGGDVDI--MDLEV-MVATMA--------
------------------------------------------------------------
------VVLF-------ILVKGPMVVV-D-------------------------------
---QDMETKV------VEDMMVTMKDEKLAVGTMVVVGTIMILEIIVDNSNQIMDP----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-DLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGSVVEPKR-AVSREDS-VKPCAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGSGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGSNY---
-GGGGNYNDFGNYSGQQQSNYRPMKG-GSFAGRSSG----SPYGGGYGSG----------
GRSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------MHDPH--SPTS---RRSRGFGFVTYSC---VEEVD
AAMCAQPNKVDGRVVEPKR-AVPREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIENIEVMDDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGHGGGSGNF-MGH-GGN------FGGG---GGNFGR--
-------GGYGGGG--------GGSRGR--YGGGDGGY--NGFGG-DGGNYGGGPGYR-S
RGGCGGGGP--G--Y--------G-NQGGGYGGR----G-GGNDGYNEGGNFGGG----N
YGGGGNYNDFRNYSGPQQSNYGPMKGG-SFGGRSSG----SPYAGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------PQGHDPKEPEQLRKLFIAL--SF
E--T--TGLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVE PKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGG----GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGCG-G--PGYSSRGGYGASGHQGGRYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------------------------------MGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVHGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYSGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYSG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---E-EVD
AAMCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTG-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCGGGSGNF-MGH-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GA-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
SGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------M-GH--
---T--HRL----CGHE--------RS-----PSFV---TH----------S---CVEVD
AAMCARPHKVDRCVVEPKR-AVSREDS-VKPVAHLPMKKIFVRGIKEDTE-EYNLRDYFE
KY---GKIETIEVMKDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYH----TING
HNCEVTKALSKQEMQSA-GSQRGHGGGSGNF-MGR-GGN------FGGG---GENFGGY-
----------GGGGGG--------SRGS--YGG-----------G-DGGNYGGSPGYS-S
RGGYGGGGPG----Y---------GSQGGGYGGG------GGYDGYNEGGNFGGGK----
TI----N------DFGNY--------------------------SGYGSCG---------
ES-GGYGSSR-------------ATV----------------------LSRRESEELSGK
LQVTLRQLSQI-------------------LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPNEPQHLRKLFIG-GLSF
ETND--DSL----REHFEKWGTLTDYS-------QT---KRSRGFGFVTCSC---VEEVD
AAMCAQPDKVDGR VVKPKR-AVSREDS-VKPGAHLTVKNIF YGKIETTEV------M---
--------------EDRQSGKK---RGFAF-AAFDD-HDTVDKIVVQ--KYHI----ING
HTCEVQKALSKQEMQSA-GSQRGRGGGSG---------N------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGRY--NGFGG-DGGNYGGGPGYS--
RGGYGH-DGP-G--C--------G-NQGGGYGGG----G-GGYNGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSLG----IPYGGGYESG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------------KEAEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCAQPHKVDGR VVEPKR-TVSREDS-VKPGAHLTVKK IFVGGIEEDTE-EYNLRDYFE
KY---GKIETIEVTEDRQSGKK---RGFAF-------------------KYHT----ING
HNCEVKKALSKQEMQS-TGLQRGQGGGSGNF-MGH-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDDGY--NGFGG-DGGNYGGGPGYS-N
RGGYGG--GP-G--Y--------G-NQGGGYGGG----G-GGYDGYNEGVNFG-G----N
YGAGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYRSG----------
GGSGEYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------MI--RSPD---QRSKGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKKIFVG-------------DYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-RDTVDKIVVQ--KYHT----ITG
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-RGN------FGGG---RGNFGRGG
NFGG--RGGYGGGG--------GRSTGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGG-GGP-G--Y--------G-NQGGGYGGD----G-GGYDGYNEGENFGGG-----
----TNYNDFGNYSGQ--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------TKWRIGPQWPPPSSAARKESAG--------LEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGG----GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG-GDG------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------RH------RR--RWQEGHDPKEPERLRELFIG-GLNF
ETTD--DSL----REHFEKWGILTDCVVMR--DPQT---KHSRGFGFVIYSC---VEEVD
AA MC-----CKSV-------PISREDY-LKSDAHLTVKK IFVGGITEDTE-EYNLRDYFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VIFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKVLSKQEMQSA-GSQRGRGGGSGNF-MGH-GVN------FGGG---GGNFGGGG
NFGG--RGGYGGGG--------GGSRGS--YGGSDGGY--NGFGS-DSGNYGGGPGYS-S
RGGYGGGGP--G--Y--------G-NQGGEYGSG----G-GGYDGYNEGGNFGSR----N
HGGGGNYNDFENYSGQQQSNYGPMKGG-SFGGRSSG----SPCGSGYGSG----------
GGRGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRREEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCV-----DGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGSFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSSRL-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------EVKLPPGRPQPDSG-----------CRRGEEGHDPKEPEQLRKLFIG-GLSL
ETTD--DSL----REHFEKWD------------PQT---KHSRGFGFVTYSS---VEEVD
AAM CARPHKVDGSVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDRE-EYNLRDYFE
KY---GKIETIEVMEDRQ----------------------IDKIAVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGCGG
NFGG--RGGCRGGG--------GGSRGS-Y-AGGDGGY--NGFGG-DGGNYGGGPGYHRS
RGGYGGGG-P-G--Y---------GNQGGGYG-----GGGGGYDGYNEGGNFGGG----N
HGGGGNYNDFGNYSGPQ-----------HFGGRSSG----SPYGGGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------------KEPEQLRKLFIG-GLSF
ETTD--DSL----REYFEKWGTLTDCVVMR--DPQP---KCSRVFGFVTYSC---VEEVV
AA MCAQPHKVHGLVVEPKR-AVPREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIEAIEVTEER--------RGFAF-VTFED-YDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCGGGSGNF-MGR-GGN------FGGG---GENFGQGC
-------------GGG-----GGGSRGS--YGGGDGGY--NGFGG-DGGNCGDGPGYS-S
RGGYGG-GGP-G--Y--------G-NQGGGYGS-----G-GGYDDYNEGGNSGGQ-----
------------------SNYEPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGCPQPDSGSRH--------RRWGEEGHDPKEPEH-----------F
ETTD--DSL----REHFEKWGTLTDCLVMR--DPQT---KRSRGFGFVTYSC---VTEVD
AAMRARPFKVDGR VVEPKR-AVSREDS-VKPGAHLTVKK IFVGSIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAS-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALAKQVMQPA-GSQRGRGGGSGNC-MGH-RGN------FGGG---GGNFGHDG
NFGG--RGGYGGGG--------GGSRGS--YGGGDVDI--MD------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------------MEGLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTFTDCVVMR--DPQT---KHSGGFGFVTYSC---AEEVD
AAVC ARPHKVDGRVVDPKR-AVSREDS-VKPGAHLTVKKI--------------------
FY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIIVQ--KYHT----ING
HNCEVKKVLSKQEMQSA-GSQRG---GSVNF-MGR-GGN------FGGG---GGNFGHGG
NF-----GGYGGGG--------GGSRGS-YGGGD----------S-DGGNYGWWSWLH-S
RRSYGGGG-P-G--Y---------GNQGGGYAG----GAGGGYDSYNEGGNFGGG----N
YGG-GNYNDFGNYSGQQQSNYGPMRGG-SFCGRSSG----SLYGGSYGSGG----GS---
---GGYGSRQFSKITEKG-------------------------YIS--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GG------
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGCRR------RH--RREEGHDPKEPKQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQA---KRSRGFGFVTYSC---VEEVD
TAM CARPHKVDGHVVEPKR-AVSRKAA-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVTEDRQSGKK---RGFAF-VTFYD-HDTVDKIVVQ--KYHT----IN-
----VKKALSKQEMQS-AGSQRGCGGGSGNF-MGC-GGN------FGGS---GGNFGCGG
NSGG--RGGYGGGG--------GGSRGS--YGRGDGGY--NGFGD-DGGNYGGGPGYS-S
RGGYGGG-GP-G--N--------G-NQGGGYGGG----G-GGYDGYNEGGNFGGS----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRRSG----SPYGSGYGSG----------
GRSGEDGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
---------------------------------PQT---KCSRGFGFVTFSC---VEEVD
AAMCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKNIFVGNIKKDTE-EYNLRDYFE
KY---GKIKTAEVMEDRWSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRG-GGRSGNF-MGH-GGD------FGG------------
------------------------------------------------------------
---------G-G--Y--------G-NQGGGYGSG----D-GGYDGYNEGGNFGG-----N
YGGDGNLNDFGNYGGQQQSNYGPMKGG-SFGGRISV----IPYGGDYGSG----------
GRSGGYGSRSF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRTQPDSSRRRRRHG--------EEGHDPKEPKQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DRQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDA-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVMEDRQSGKK---REFAF-VTFYD-HDTVDKI-VQ--KYHT----ING
HNCEVKKAFSKQEMQSR-G----RGGGSGNF-MGR-------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GSFGGRSSG----SPYGGGYGSGG---------
-GSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVV EPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGG----GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDFVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGHVVEPKR-AVSREDS-VKRGAHLTMKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIE-------------RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGH-GGN------FGGD---GGNFGRGG
NFGG--RGGYGGEG--------GGSRGS--YRGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNN---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGKSSG----SPYGGGYGSG----------
GGSGGYGSRRFKKKKQKR-------------------------ATVLS--RRESEELSGK
LQVTLRQSS---------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------M-GH--
---T--HKL----CGNE--------RS-----SNKT---LQRLWF---------------
-SVCAGPHKVDGHVVEPKR-AVSREDS-VKPGAQLTGKKIFVGGIKEDTE-ECNLRDYFE
KY---GKIETIEVMEDRQ--------RFAS-VTFDD-HDTVDKIVVQ--KYH----TING
HNCEVKKALSKQEMQSA-GSQRGHGSGSGNF-MGR-GGN------FGGG---GGSFGRG-
-------GN-FSGGGG--------SRGS--YG-GDGRC--NGFGG-DGGNYGGGPSYS-S
RGGYGGGGRG----Y---------GNQGGGY----------GYDGYNEGGNFGGGN----
YGGGGNY------DFGNYSGQQQSNYG-PMKGGSSG----SPYGGGYGSGG---------
-----------------------GSV----------------------LSRRESDELSGK
LQVTLRQ-----------------NWKN--LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKLPPGHPQPDSGPRC--------CRWGEEGHDQKEPEQLRKLCIG-GLSF
ETTD--NSL----REHFEKWGTLTDCEVMR--DPQT---KHSRVDA-AMH----------
----ARPHKVDGRVAEPKR-AVSRKDF-VKPGAHLTVKKIFVGGIKEDTE-E--------
---------------------L---RGFAF-VTFDD-YDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQST-GSQRGRGGGSGNF-MGR-GGN------FGGG---RGNFGRGG
NFGG--RGGCGGGG--------GGSRGS-YGGGDDGGY--SGFGG-DGGN----------
GGGYGGGG-P-G--Y---------GNQGGGYGG-----GGGGYDGYNEGGNFCGH----N
YGDSGNYNDFGNYSGQQQSNYVPMKGS-SFDGRSSG----SPHGGGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEDHDPKEPEQLRKLFIG-GLSF
ETTD--TSL----REHFEKWDTLTDCVVMR--DPQT---KCSRGFGLGTYSR---VEGMD
AA MCGRPHKVDGCVVEPNR-A--GEDS-VKPGAHLTVKET FVGGIQEDAE-EYNLRDYLE
KY---GEIETIEVMEVRQSGNE---RGFAF-VTFDD-RDTVDKIVVQ--KYHT----LHG
HNCEVEKALSQQEMQSA-GPQRGRGGGSGDF-MGR-GGN------FGGS---GGNFGRGG
NFGG--RGGYGGGD--------CGSRRS--YGGGDGGY--NGFGG-DGGNYGGGPGYG-S
RAGYGA-----G--Y--------G-NRGGGYGGG----G-GGCDGYNERGNFGGG----N
YGGGG----------QQPSNYGPMQGG-SFGGRTSG----SPCGGGYGSG----------
GGSSGYGSSRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------LCGN-ER--PPNK----TFQGLWF-------------
-SMCARPHKVDGPVVEPKR-AVSRKDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIEIIEVMEDRQSGKK---RGFAF-VTFND-HDTVGKMVVQ--KYHT----ING
HNCEVKKALSKQEMRSA-GSQRGCGGGSGNF-MGR-GGN------FGGG---G------G
NF-G--HGGYGGGG--------GGSRGS-YRGGD-GGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG-P-G--Y---------GNQGSGYGG------GGGYDSYNEEGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGLMKGG-SFGGRSSG----SPYSGGYGSDG----GS---
---DGYGSR-----RNCK-------------------------NLPQK---E--------
-----------------------------------R------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRCR------RH--RGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTNCAVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKTETMEVMEDRQSGKK---RGFAF-ATFDD-HDTVDKI-VQ--KYHT----ING
HNREVKKALSKQEMQS-AGSQRGCGGGSGNF-MGH-GGN------FGGG---RGNFGHGG
NFGG--RGGYGGGG--------GCSRGS--YGGGDGEY--NGFGG-DGGNCGS-------
-GGYGGG-GP-G--Y--------G-NQGGGYGG-----G-GGYDGYNEGGNFGGG----N
YGGGRNDNDFGNYSGQQQSNCEPMKGS-SFVGRISG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------EAARPPSARPDRPGTGHDPKEPEQLRKLFIG-GLSF
ETAD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCVRPHKVDG RVVEPKR-AVSREDS-VMPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQ--------RFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSPRGRGGGSGNF-MGH-GGN------FGGG---GGNLGCGG
NFGG--RGGYGGGG--------AGSRGR--YGGGDGGD--NGFEG-DGGNYGGG------
----CGGGGP-G--Y--------G-NRGGGYGGG----G-GGDDGYNEGGNFGGGNC---
-GGG------------------------AVLVESSG----SPCGGGY----------GSG
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------PKEPEQLRKLFIG-GLSF
ETTD--DGL----REHFEKWGTLTDCVVMR--DPQT---KRSRDFGFVTYSC---VEEVD
AAVCARPQKADGRVVE PKR-AISREDS-VKPGAHLTVKK IFVGSIKEDTE-EYNLRDYFE
KY---GKIETIEVMGDRESGKE---RGFAF-ITFDD-HDTVDKIVVQ--KYH----TING
HNCEVKRPFLNK------------------------------------------------
-------------------------------------K--CNLEV-MVATMA--------
------------------------------------------------------------
------EVLA-------IVVEEAMVVE-D-------------------------------
---QDMETKVVGMVEVVEDMMVTMKEEILAVINVVMVGTIMILEIIVDNSNQIMD-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDS-------------RTGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL---------------NCVVMR--DSQT---KRSRGFGFVTYSC---VKEVD
AA MCARPHKVDGPVVEPKR-AVSREDS-VKPGAHLTMKN VFVAGIKENTE-EYNLTYYFE
KY---GKIETIE------SGKK---RGFAF-VTFND-HDTADKIVVQ--KYHT----IHG
RNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGH-GGN------FGSG---GGNLGRGG
NFGG--RGGCGGGG--------GGSRGS-YGG------------G-NGGNYGSGPVYS-S
RGAYGGSG-P-G--Y---------GNQG-----------GGGYDGYHEVGNVGGG----S
YGGGGNYNDFGNYSGQQQSNYGPMNRG-SFRGRSSG----SPYGGGYGSGG----GS---
---GGYGIAGGS------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------R------RRRKRGREGHDPKEPEQLRKLFIG-SLSF
ETMD--DSL----REHFK-WGTLSDFAVMR--DPQT---KHSRGFGFVTYSC---VEEVD
AAMCAQPHKVDGHV VEPKR-SISREDS-VKPGAHLTMKK IFVGGIKEDAE-EYNLRDYFE
KY---GKIKTIEVMEDQQSGKK---RGFAF-VTFDD-HDTVDKIFV---KYHT----ING
HNCESKKALFKQEMQSS-GSQRGCGGGSGNF-MGQ-GGN------FEGG---GGN-----
-FDG--RGGYGDGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGGP-G--Y--------R-NQGGEYGGG------GGGDGYNEGGNFGGG----N
YDDSGNYNGFGNYSGQKQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKL-------------------------------PLPPQLRKLFIG-GLSF
ETTN--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSY---VEEVD
AA MCAQPHKVDRCIVEPKR-AVSREDS-VKPGLHLGVKK LFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VTFDD-HDRVDKIDVQ--KYHT----ING
HNCEWW-GLSKQEMQSV-GSQRGHGGGSGNF-MGR-GGN------FGGG---EGNFGCDG
SFGG--RGGYGGGG--------GGSRSS--YGGDDGGY--NGFGG-DGGSYGSGPGFS-S
RRGYGGGGP--G--Y--------A-NQGGGYSGG----G-GGYDGYNEGKIFGSD----N
YGGVGNYNDFGNYSGQQQSNYGTMKGG-SFDGRSLG----SPYGGGYGSG----------
GRSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------PKEPEQLRKMFIG-GLSF
ETID--DSL----REHFEKWGTLTDYVVMR--DPQT---KYSRGFGFVTYSC---VEEVY
AAMCAQS-HADGKVVESKR-GV SRKDS-VKPSAHLTEEK IFVGGIKEDTE-EYNLRVYFE
KY---GKIESIEVMEDKQSGKK---RGFAF-VTFDD-QDTVDKIVTQ--KYH----TING
HVCEVKRPFL--------------------------------------------------
-------------------------------------K--CNLEV-MVATMV--------
------------------------------------------------------------
------VVLD-------IAVEKAMAVV-D-------------------------------
---QDMETKVVDTVVVVEDMMVPVKEEVLVVVTMGV--IAMILEIIVHRSNQIMD-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPLPGHPQPNSSHCS-SQG--------EEGHDPNEPEQLRKLLIG-SLSC
ETA----DL----REHFEKWDTLTDCVVMR--DLQT---KCSRGGCSNVC-------SIT
QGFCKA-------------------------------------WSLTVKK-IFNLRDCFE
KY---GKIETIEVMEDRQNGKK---RRLAF-VTFND-HDTADKIVVQ--KYH----TNNG
HNCEVKKALSKQEMQSA-GSQRGRGCGSGNF-MGC-GGN------FGSD---GDNFGCGG
NFGG--RGGYGGGGGG--------SRGS--YGGGDGGY--NGLGG-DGGNFPQCSRGG-Y
GGG----TRG----Y---------GNQGGGYGGG----G-GGYDGHSEGGNFGGGNYS--
--GGGNYNDFGNYSGQQQSNYGPMKEG-SFGGRSLG----SPYGGGTG--V---------
GS-GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------PKEPEQLRKLFPR-GLSF
ETTD--NNL----REHFERWGTLTGCVIMR---AQT---KHSRGFGFMTFSC---AEEVN
AAMYSWPHKVDGHVVE SKR-AVSREDS-VKPDAHLMVKT IFVGGIKKDTE-EHNLRDDFQ
MF---GKIETIDVMVDRQSGK----RGFGF-VTFDD-HHTVDKIVVQ--KYL----TING
HNCEVKRPLLNK------------------------------------------------
----------------------------------------RNLEL-IMVTMV--------
------------------------------------------------------------
------VVLV-------IIVE--VAVV-E-------------------------------
---QDMETKVVDKV-VEEDMMVTMKGKILVIVTMVM--AEIILEIIVDNSNQIRD-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------VNGHDPKEPGQLRKLFIG-NLSF
ETTD--DSS----REHFEKWGTLTNCEL------QT---KHSRGFGFVTYSC---VEEVD
AAMCARPHKVDGR VME-KR-AVSRED-------------S FVGGTKEDTE-EYNLRDYFE
KY---GRIEAIEVMEDRQCGKK--QRIWGNACDSKE-CDTVNKIVVQ--KYH----AVNG
HTCEVKKALSRQEMQFA-GLQRGCGGKSGNI-MGW-GGN------FGGG---GGNFGHGN
SGNCGIGPSYSSGGGDGGGGPGYGNQGG--GYGGKGGY--NVYNE---------------
------------------------------------------------GGNFGSGN----
YGGSGNYNNFRNYGQQQ-SNYGPIKG--HLGGRSLG----SPCGGGYGSGD---------
GSGR-Y------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MDVKPPPGRPQPEFGHRR------RRRRTGEEGHDPKEREQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLPDCVVMR--DPQS---KRSRGFGFVTYSC---VEE VD
A--------VDGRVVEPKR-AVSREGS-IKPGAHLRVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVMEDRQSGKK---RGFAF-VTLDD-HNTVDKIVVQ--KYNT----ING
HNCEVKNALSKQEMQSA-GSQRGLGGESGNF-MGS-RGN------FGGG---VGNFGGGG
NFGG--RGGYGGGG--------GGCSEP--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----SEHFEKWGPLTDCVVMR--DPQT---KRSRGFGFV-----------D
AALCAQSHKFDGRVVEPKR-AVSREGS-VKPGIHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIE-------------RGFAF-VTFDD-HDKVDKIVVQ--KYHT----ING
HNCGSG------NFTG------------------C-EGN------FGGG---GGDFGHGG
NFGG--RGGYSGGG--------GGIRGS-YGGGD-GGY--NGFGG-DGGNYGGRPGYS-S
SGGYGGGG-P-G--Y---------GNQGGGYGG-----GGGGYNGYNEGGNFGGG----N
YDGGGKYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGVGYGFGG----GS---
---GGYGSRTF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGLGRCHGG--------EEGHDPKEPEQLRKLFTG-GL--
-------S-----FEHFEKWGTLTDCVVMR--DPQT---------------K---RSGVD
AAVCARPHKVDGRVAEPKR---------AV-SREDSVKEIFVGGIKEDTE-DYNLRDYFE
NY---GKIETVEVTEE-----R---QRFAL-VTFDD-HDTADKIVV Q--KYL----TING
LNCEVNKALSKQELQSA-GSQRGCGGGSGSF-MGR-GGN------FGGG---GGNFGRGG
NFG---------------------------------------------------------
--------------------------------G---------DDGYNDRGDFGGGN----
H GGGGNYNDFGNYGGQQQSNYGAMKGG-SFGGRSPG----SPCGG---------------
GS-GGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGGY---
-----------------------------------------------GSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFLG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AA TCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---SKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVLQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NSGG--RGGYGGGG--------GGSRAS--YGGGDGGY--NGFGG-DGGNYGGSPDYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYDGGYGSG----------
GGRGGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRCR--------RRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VNPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGV--------GGSRGS-Y-GGG--------------------------
---------------------------------------DGGYNGFGDGGNYGGG----P
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX----XXXXXXXXXXX----XX---
---XXXXXXXXXXXXXXX-------------------------XXXXX---XX---XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKKKKKKG

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETAD--DSLR----EHLQKWGTLTDCVVMR--DPQT---KGSRGFGFVTYSC---VEEVD
AA TCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDKE-EYNLRDYFE
KY---GKIEAIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKI-VQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GVSRDS--YGGGDDGY--NGFGG-DGGNYGGGPDYS-S
RGGYGGG--G--PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGSGNYG--
--GGGNYNDFGNHSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGEYGS----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------MR--DPKT---KRSRGFGFVTYSC---VEEVD
AAMYARPHK---RVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDCFE
NY---GKIETIEVMEDRQSGKK---RGCAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-GGGNYGGGPGYS-S
RGGYGGGGPG-G--Y--------G-NQGGGYGGG----G-GGYDGYNEGGNFG-G----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGRRRK-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------PHKVDGQVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRD---
HY---GKIETIEIMEDRQSGKK---GGFAF-LTFDD-QDAVDKIVVQ--KHHI----IHG
HTCEVKRALFEQDRQSA-GSQRGHGGGSGNF-MGR-GGN------FG-------------
-----------GGG--------GGRRGS-YGGSY-GGY--NGFGG-DGGDYGGGPGYR-S
RGGYGGGG-P-G--Y---------GNQGGGYGG-----CGGVCNKRQNVVLL--------
------------------------------------------------------------
-----------------------------------------------S---CMVKCLSFV
LQMLCR------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
VAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---SKIETIEVMEDQQSGKK---RGFAF-VTFDD-HDTVDKVVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRG-
--------GYCGGG--------GGSRGS--YGGSDGGS--NGFGG-DGGNYGGGPGYS-S
RGGYGSGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQ----------------SSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------RHHRRWQEGHDPKEPERLRELFIG-GLNF
ETTD--DSL----REHFEKWGILTDCVVMR--DPQT---KHSRGFGFVIYSC---VEEVD
AA M-----------------------------------------------------Y YFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VIFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKVLSKQEMQS-AGSQRGRGGGSGNF-MGH-GVN------FGGG---GGNFGGGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGS-DSGNYGGGPGYS-S
RGGYGGG-GP-G--Y--------G-SQGGEYGSG----G-GGYDGYNEGGNFGSR----N
HGGGGNYNDFENYSGQQQSNYGPMKGG-SFGGRSSG----SPCGSGYGSG----------
GGRGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGAQGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP--GGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--HPQT---KCSRGFGFVTYSC---VEEVD
AAMCARPHKVDGH VVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KHHT----ING
HNCEVKKALCKQEMQSA-GSQRGRGDGSGNF-MGR-GGN------FG-------------
-----------------------------------------------GGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQ--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------MAAIKEEREVEDYKRKGRRSS--------QGHEPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMSARPHKVDGRVVE PKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLREYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQTA-SSQRGRGGGSGNF-MGR--GN------FGGG---GGNFGRGG
NFGG--RGGYGGGG-G-----GGGSRGS--FGGGDG-Y--NGFGDVKGGNYGGGPGYG-S
RGGYGGGGGP-G--Y--------G-NPGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSG----SPYGGGYGSG----------
SGSGGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------------------MDPEGHDPKEPKQLRKVFIG-GLSF
ETTG--DSL----REHFEKWGTLTDCVVMR--DCQT---KRSRGFGFVTYSC---VEEVD
AA MCAPPHKVDGA--------VSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYTLRDYFE
KY---GKIKIIDVMEDRQSGKK---RGFAF-------------------KYHT----ING
QNCEVKRALCKQEMQSA-GSQRGRGGGSGNF-MGH-GGN------FGGG---GGNFGCGG
NFGA--RGGYGGGG--------GGSRGS-Y-GGGDGGY--NGFGS-DGRIYGGSPDYN-S
RGGYGGGG-P-G--Y---------GNQGGGYGGG------GGYD-----GNFGDG----N
YGGRGNYNDFGNCNGQQ-------KGG-GFGGRSSG----SPYGGGYGSGG----GS---
---GGYGSRRFKKTTEKG-------------------------YSS--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------MARNTKPSPGRKL-------LRVLKMEGHDTKEPEQLRKLFIG-GLSF
ETT---DSL----REHFEKCGTLTDCVVMR--DHQT---KCSRGFGFVTYSC---VDEVD
AAM CARPHKVDGCVVEPKR-AVSREDS-VKPGAHLKVKK IFVGVMKGDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-MTFDD-HDTVDKTVVQ--NYHT----ING
HNCEVKKALSKQEMRSA-GSQRGYGGESGNF-MGR-GGN------FGGS---GGNFGHGG
NFGG--RGGCGGGG--------GGSRGS--YRGGDGEY--NGVEG-NGGNYGGGPGYS-S
RGGYGGGGP--G--Y--------G-NQGGGYGGG---GG-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKQPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVE PKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GG--PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---SGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG-----SYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKLQPAHSQADS---TCHCH--------REG-GGAEPEQLKKLFIG-DD--
-------SL----REHFEKWGTLTVCGKTR--KQNV---P----GGFVTYSC---VEEVD
AAICARSHKVDGRVVEPKR---------AV-SREDSVKKFFVDGIKEDTE-EYNLRNYFG
KY---GKIETIEVMEDIQSGKK---RGFAF-VTFDD-HDTIDKIVVQ--KYH----TISG
HNY---------EMQSA-GSQRGPGGGSGNF-MGC-GGN------FGGG---GGNFGPGG
RYG---------------------------------------------------------
--------------------------------GG----G-GGYDGYYEGGNFGGGS----
Y GGDGNCNDFGNYSGQQQSNYGPMKGG-SFAGRSSD----SPYDG---------------
GS-GRYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGSR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSRRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGNYGGGG--------GAWCTRQCLERGRKSY----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------MACKEEREVEDYKRRGRRS--------SQGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMAARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQTA-TAQRNRGSSSSNF-VGR--GN------FGGS---SGSYGRGG
GFGG--RGGYGGGSGG-----GGGSRGS--FGSGDG-Y--NGF--GDGGSYGGSPGYG-S
RGGY-G-GSP-T--Y--------G-NPGGGYGGG----G-GGYDGYNEGGNFGG-----N
YGGSGSYNDFGNYSGQQTSSYGPMKGGGSFSGRSSG----SPYGGGYGSGG----GGGGG
GGSGGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------RH------RR--RWQEGHDPKEPERLRELFIG-GLNF
ETTD--DSL----REHFEKWGILTDCVVMR--DPQT---KHSRGFGFVIYSC---VEEVD
AA MC-----CKSV-------PISREDY-LKSDAHLTVKK IFVGDITEDTE-EYNLRDYFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VIFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKVLSKQEMQSA-GSQRGRGGGSGNF-MGH-GVN------FGGG---GGNFGGGG
NFGG--RRGYGGGG--------GGSRGS--YGGGDGGY--NGFGS-DSGNYGGGPGYS-S
RGGYGGGGP--G--Y--------G-NQGGEYGSG----G-AGYDGYNEGGNFGSR----N
HGGGGNYNDFENYSGQQQSNYGPMKEG-SFGGRSLG----SPCGSGYGSG----------
GGRGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------------------------------QLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGCGFVTYSC---VEEVD
AAM CTRPHKVDGRVVEPKR-AASREDS-VKPGAHLTVKK IFVGGIKEDTE-ERNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGPAF-VTFDD-HDTVDKIVVQ--KYHT----IHG
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-TGC-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--NGGGD---------G-DGGSSGGGPGYS-S
RGGYGGGGP----GY---------GNQCGGYGG----DG-GGYYGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SAYGGGYGSG----------
G---RYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGG-GGP-G--Y--------G-NQGGGYGGG---GG-GGYDGYNEGGNFGGG----N
YGG-GNYNDFGNYSGQQTTKSAVSEQ----------------------------------
--TGGYLVRSAFQVLNPQ-------------------------STRI-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------EVKLPPSLPQPKSSHCHHCQR--------KEVHDPKEPEHSRKLFIG-GLR-
---------------RFEKWGTLTDCVVMR--DPQT---KRSRGFSFVIDSC---VEEVD
AKVCARPHKG----------------S-VKPGAHLIVKKISVGAIRGDTE-EYNLRGYFE
KY---GKIETVEIMEDRQSGKK---RGFAF-VTFDD-HHTADKIVVQ--KYH----SING
LNCEVEMQSAGSQRES------------GDF-MGC-GGN------FGGG---GGNFGHGG
NFGG--RGGYGGGWGG--------SRGS--DGGGDGGC--NRLGG-DGGNYGHGPGYR-R
GGG----GY-----------------GGGGPGY-----G-NQGDMYGAGGGYDGDNEGGN
F-GAGNYNDFGNYSGQQQSNYGHMKSC-SYGG---G----YGSG------G---------
RS-GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------------------------------MGIPEGHDPKEPEQLRKPFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGHVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDME-EYNLRDYFE
KY---GKIETIEVMGDRQ--------KFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGDGSGNF-MGR-GGN------FGGG---GGNFGCGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGG--G--PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPCGGGYGSG----------
VGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------GRLAEPPGKRLQPVKMFMFWGE--------FHGHDSKEPEQLRKLFIG-GLSF
ETTG--DSL----REHFEKWAHSQIVDPHT--KSS---------------RG---FSLVD
AAMGAQPHKVDGAVPREDS---------VKPGAHLTGKKIFVGGIKEDSE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFVF-VTFDD-HNTVDKIVVQ--KYH----T ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-VSL-GGN------FGGG---SYGGGDSG
GC----------------------------------------------------------
--------------------------------GV----G-GGYDGYSEGENFGGGN----
Y GGGQNYNDFGNYSCQQQSNYRPMKGG-SFGGRSGG----YGPSG---------------
GS-GRYGRRRFL------KKQQKRAIGEGF------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------KP------PISGLKMEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDRVVMR--VPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCGGGSGNF-MGC-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGTR--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGDYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSD----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEAEQLRKLFIG-GLSF
ETMD--DSL----REHCEKWGTLIGGVVMR--DPQT---S-----------------EVD
AAGCARPHKDDRALIL--------------E-----RTKIFIGGIKEDTE-EYNLRGCFE
KY---SKIETVEVMEDRQ--------RFAF-VTFDD-HDTVDKVAVQ--KYH----TVSG
HDCEVKKALSEQEMQSA-GSQRGCGGGSGIF-MGC-GGN------FGGG---GGNFGHGG
NNGG--GGGYGGGGGG--------SRGS--YGGGDCGY--NGFGG-DGGNHGGGPGYR-Y
GGG----GPG----Y---------ENQDGGYGHG----G-GGYGGDNEGGNFGGGNYA--
--GGGNYNDFGTYSGL------------HFGGGSSG----HPYGGGCGSGG---------
GS-GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------GHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRHRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-ECNLRDYFE
KY---GKIETIEVMEDMG-------GGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGG----GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGG-G---PGY---------GNQGGGFGG----SG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFXGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRXSGKX---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------LCGN-ER--PPNK----MVQGLWF-------------
-CD--------LFLLEPKR-AVSREDS-VKPGAHLTVKKIFLGGITEDTK-EYNLRDYFE
KY---GKIETIEVMQERQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSRTGRGGGSGNF-MGC-GGS------NFGR---G------G
NFGG--RGGYGGGG--------GGSRGS-YGGGD-GGY--NGFGS-DGGNYAGGPGYS-S
RGGYGGGG-P-G--Y---------GNQ-------------GGYDGYNEGGNFGGG----N
Y GGGGNYNDFRNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYASSG----GS---
---GGYGSR-----RNCK-------------------------NLPQK---E--------
-----------------------------------G------------------------
------------------------------------------------------------
-------------------------------------------

-------------PLCPYHSLG--R------GKSGLKMEGHDPKKPEQSRKLFIG-----
--------------EHFEKWGTLTDCVVMR--DPQT---KCSRGFGFVTYSC---VEKVD
AAM CARPHKVDGRVVEPKR-AVSRENS-LKPGAHLTVKK IFVGGIK-DTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KY---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

MSPVVWSQNGGKTAAQLQPNCSRCHHCGG----GVVGEKGHDSKEPELLQKLFIG-GL--
-----------------SFETTDDNCVVMR---PQK---KRSRGFGFVTYSC---VEEVE
AARCAGPHKADRCVVEPKR-AVSIEDS-VKSGAHLTVRKIFVGGIKEETE-EYNLRDYFE
KY---GKIEIAEVVEDRQSGKK---TGFAF-ITFDD-HDTVDKTVVQ--K YH----AING
HNCEVK---------K------------ALS-K--------------QE---IGSFGCGG
NSDG--RGGYGGEGGG--------SRGS--YGGGDGGY--NGFGG-DGGNYGGSPGYS-S
RG-----GY-----------------DGDGPRI-----W-W-----CEGGNFGGGNYG--
--GGGNYNDFGNYSEQQQSNYEPMKGG-TFGGRSSG----IPQG------G---------
ES-GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRCR------RH--RGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTNCAVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKTETMEVMEDRQSGKK---RGFAF-ATFDD-HDTVDKI-VQ--KYHT----ING
HNREVKKALSKQEMQS-AGSQRGCGGGSGNF-MGH-GGN------FGGG---RGNFGHGG
NFGG--RGGYGGGG--------GCSRGS--YGD--------------GGNCGS-------
--GYGGG-GP-G--Y--------G-NQGGGYGG-----G-GGYDGYNEGGNFGGG----N
YGGGRNNNDFGNYSGQQQSNCEPMKGS-SFVGRISG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPNSGHR-----------RGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAV CAGPHKVDGRVVEPKR-AISREDS-VKPGVHLTVKK IFVCGIKEDTE-EYNLRDYFE
KY---GKIETMEVMEDRQSGKK---RGFVF-VTFDD-HDAVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSSNF-MGR-GGN------FGGG---GGNFGCGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGEYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GNFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------VEKTFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTHSC---VEQAD
AAMCAQRHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GRIETTEVMEDMQSGKK---RGFAF-ATFDD-HDTVDKIVVQ--EYHT----ITG
HNCEVKKVLSKQEIQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---RGNFGHGG
NFGG--RGGYGDGG--------GGSRGS--YGGGDGGY--NGF-G-DGGNYGGGPGYS-R
G-------------Y--------G-NQGGGYGGR-----GGGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPDGGW--VSRKNVG----TPVGGA--------------
-SPQAQGARES-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------MEVKPPPPGSSRRCWREEGHDPNEPEQLRKLFIG-GLSF
ETTD--DSF----REHFEKWGTLTDCVVMR--DPQT---KHSRGFGSVTCSC---VEEVD
AAMCAQPHKVDGRVVKPKR-AVSREDS-VKPGAHLTVKNIFVGGVKEDTE-EYNLRE---
--------------LLRKGGKK---RGFAF-ATFDD-HDTVDKIVVQGRKYHT----ING
QNCEVQKALSKQEMQSA-GSQGGRGGGSG---------N------FGGG---GGNFGRGG
NCDG--RGGYGGGG--------GGSRGS--YGGGDGRY--NGSGG-DGGNYGGGPGYS-S
RGGYGH-DGP-G--C--------G-NQGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSLG----IPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGHRR------RR--RWEEGHDPKEPEQLRELFIG-GLNF
ETTD--DSL----REHFEKRGILTDCVVMR--DPQT---KRSRGFGFVIYSC---VEEVN
AA MC-----CKSVP-------ISKEDY-LKSDAHLTVKK IFVGGITEDTE-EYNLRDYFE
KY---GKTETTEIMEDRQSGKK---RGFAF-VIFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKVLSKQEMQSA-GSQRGRGGGSGNF-KGH-GVN------FGGG---GGNFGLGG
NSGG--RGGYGGGG--------GGSRGS--YGRGDGGY--NGFGS-DSGNYGDGPGYS-S
RGGYGGGGP--G--Y--------E-NQGGEYGSG----G-GGYDGYNEGGNFGSH----N
YGGGGNYNDFGNCSRQQQSNYGPMKGG-SFGGRSSG----SPCGGGYGSV----------
GGRGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------THEPKEPEQL-ELFIC-GLSL
ETTD--GSL----REHFEKWTL--DCVVMR--DPQT---KCSRGFGI VISSC---VEEVD
AAGCA--HKVGGRVVEPKR-AVSREDS-MKLGAHLTVKE IFVGGIKEDTE-EYNFRDYFE
KY---GKIETIDVMEHRQSGKK---GGFAC-VTFDD-HDTVDNIV-V--QYP----TSNG
RDCEVKRALSKREMQSA-GPQRGRGGGWGNF-GGR-GGC------GGGG---GGSRGYNQ
------GGGYGG-GGG--------DDGY--NE--------EGFGG---------------
------------------------------------------------------GN----
YGGGGNYNDFGNYSGQQ-SNYGPMKG--SFGGRSSG----SPYGGGYGSGG---------
GS-G--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLRE--QEHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGGFESPAQTR-Q
TTT--AATKGGGPGY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------IGESG-LK--------LEGHDLKEPEQLRKLFIG-GLSF
ETTD--DSV----RVHFEKW----DCVAMR--RPQT---NRSRGFGFVTYTC---VEEVN
AA MCAWPHRVHGRV------VEPKRDS-VKPGAHLTVKK VFVGGVKEDTE-EYNLRDYFG
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDEIVVQ--KYH----TING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------VGGG---GGNFGRGG
NFDG--RGGYGGAGGG--------SRGS--YGGGDGDG--GNYGG-RRLWW-WWTGYG-N
QGGGGKGYDG----Y----------SE---------------------GGDFGGGN----
YGGGGNYNDFENYGGPGF-------GG-SSSGSPCG----G----DYGSG----------
-G--GYGNR-----------------RFFF-NTAEKSCS----------SHQESEELSGK
LQVTLRQLS---------------------------------------------------
------------------------------------------------------------
-------------------------------------------

MSPVVWSQNGGKTAAQLQPNCSRCHHCGG----GVVGEKGHDSKEPELLQKLFIG-GL--
-----------------SFETTDDNCVVMR---PQK---KRSRGFGFVTYSC---VEEVE
AARCAGPHKADRCVVEPKR-AVSIEDS-VKSGAHLTVRKIFVGCIKEETE-EYNLRDYFE
KY---GKIEIAEVVEDRQSGKK---TGFAF-ITFDD-HDTVDKTVVQ--K YH----AING
HNCEVK---------K------------IWQ-FYY-GGN------FGGG---RGSFGCGG
NSDG--RGGYGGEGGG--------SRGS--YGGGDGGY--NGFGG-DGGNYGGSPGYS-S
RG-----GY-----------------DGDGPRI-----W-W-----CEGGNFGGGNYG--
--GGGNYNDFGNYSEQQQSNYEPMKGG-TFGGRSSG----IPQG------G---------
ES-GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLSIG-RLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CAWPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMKDRQSGKK---RGFAF-VTFDD-HDTVDKTVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCGGGSGNF-MGR-GGN------FGGD---G------G
NFGG--RGGYGGGG--------GGSRDS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-R
RGGYGGCG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGSFGGGNY---
-GGGRNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GRSGGYGSRRFK------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVE PKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGG---------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGGP-G--Y--------G-NQGGGYGG-----G-GGYDGYNEGGNFGG------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLKK--REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC-----EVD
AAMCA RPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTG-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCGGGSGNF-MGH-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRTQPDSSRRR--------RRHREEGHDPKEPKQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DRQT---KRSSGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDA-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVMEDRQSGKK---REFAF-VTFYD-HDTVDKI-VQ--KYHT----ING
HNCG------------------------------------------------GGNFGRGG
NSGG--RRGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
GGGYGGG-GP-G--N--------G-NQGGGYGGG----G-GGYDGYNEVGNFGGG----N
YGGGGNYNDFGN-SGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQMRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHPTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKTVVQ--KSHT----ING
HNCEVKKALSKQEMQSA-GSQRGHGGGSGNF-MGR-AGN------FGGG---GGNFGCGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQ-----------HFGGRSSD----SPYGGGYGSG----------
GGSGGYGSRSF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------VEVKPPPGHPQLDSSHCR-HCS--------REGHDPKEPKQLRKLFIG-GLNF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KCSRGFGFVTYSY---VEEVD
AV MCAGPHKVDGQVVEPKR-AVSREDS-VKPGAHLTVKKILL------------------
-----GKIETIEVMEDRQSRKK---RGFAF-VTCDD-HDTVFKTV-Q--KYH----TING
HNCEVKNPLSKQEMQFT-RSQRAHGEGSGNF-MGH-G----------DG---RGNFGCGG
NFGG--RGSYSGGGGG--------SRGS--YGGGDGGY--NGFRG-DGGKYG--------
------------------------------------------------------------
--GCPGYSSRGGYGGGGP-GCGNQGGG-YGGGDMIG----SDVAVNYGIG----------
---RRYGSDPML------CGCGTGRWLQLRLDP-------------------S----SGN
LHMPPVQALNEKKRPKK-------IFFNL-------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPLPGHPQPNSSHCS-SQG--------EEGHDPNEPEQLRKLLIG-SLSC
ETA----DL----REHFEKWDTLTDCVVMR--DLQT---KCSRGGCSNVC-------SIT
QGFCKA-------------------------------------WSLTVKK-IFNLRDCFE
KY---GKIETIEVMEDRQNGKK---RRFAF-VTFND-HDTADKIVVQ--KYH----TNNG
HNCEVKKALSKQEMQSA-GSQRGRGCGSGNF-MGC-GGN------FGSD---GDNFGCGG
NFGG--RGGYGGGGGG--------SRGS--YGGGDGGY--NGLGG-DGGNFPQCSRGG-Y
GGG----TRG----Y---------GNQGGGYGGG----G-GGYDGHSEGGNFGGGNYS--
--GGGNYNDFGNYSGQQQSNYGPMKEG-SFGGRSLG----SPYGGGTG--V---------
GS-GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPEEPEQLRKLFIG-DLSF
ETTD--DSL----KEHFEKWGTLTDFVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
VAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLIVKK IFVGSIKEDTK-ECNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTIDKIVVQ--KYHT----ING
HNCEVKKAPFKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GCGG----
---------------G-----GGGNRGS--Y-GGDGEY--NGFGG-DGGNCGSGPGYS-S
RGGYGG-GGP-G--Y--------G-NQGGRYGG-----G-GGDDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQ------------HFGGRSSG----SPYGGGYGSG----------
GRSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVE PKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGSYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------TFY------------------
-----------------------VAGN-ER--SPNK----TLQGLRF-------------
-SMCARPHKVDGRXXXXXX-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
---------YG-GG--------GGSRGS-YGGGD-GGY--NGFGG-DGGNYGGGPGYS-S
RGGYGG-G-P-G--Y---------GNQ---------------------------G----N
YGGGGNYNDFGNYSGQQQSDYGPWKRG-SCGAR---------------------------
-----------------S-------------------------SVLSR---RESEELSGK
LQVTLRQSSQMHP------RNCKN------LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------SKEPEQLRKLFID-GMRF
ETTE--NSL----REHFEKLNTLRDCVVIG---PQT---KRSSGSCFMT YSC---LEED-
AAVC-APHKVDRGAVEPKR-AVSREDS-V----HLTVKK IFVSGINEDTE-EYNLSYYFD
KY---VKIESIEFMEDRQSGKK---RGFAF-VTFYN-HNTVYKIVIQ--KDH----TINE
HTFEVKRSFLNK------------------------------------------------
-------------------------------------K--FKLEV-MVTTMV--------
------------------------------------------------------------
------VVLE-------IAVEEVLVVV-D-------------------------------
---QDMEAKVVDTV-VGEDMVVIMKEES-LVVTMVVVGITMILEIAVDSSNQMMH-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------------MNRRRLRGEEDHDPKEPEQLRKLFIG-DLSF
ETTD--DSL----REHFEKLATLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AA MCARPHKVDGAV--------SREDS-VKPGTHLTVKK IFVGSIKEDTE-EYNLRDYFE
KY---GKIEIIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHS----ING
HNCEVKKALSKQEMQSA-GSQKGHGGGSGNF-MGG-----------------GGNFGHGG
NFGG--RGGYGGGG--------SSSRGS--YGGGDGGY--NGFGG-DGGNCGNGPGYS-S
RGGYGG-GGP-G--Y--------G-NQGGGYGG-----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYRPMKGG-SFGGRSSG----SPYGGGYGS----------G
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------------------------M--------GGSQDPKEAEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDC-----------------GFDFVTYSR---VKEVE
AAMCAQPHKVDKCVVEPKR-AVSTEDS-IKPGAHLTVKKLSVG--------EYNLRDYFE
KY---GKIETIEVMENRQNGKK---GGFAF-VSFDN-YVSVDKIVVQ--KYY----TIYK
HNCEVQRALSKQEIQFS-GSQRGYEGGPGNF-MGR-GGN------FGGG---GGNFSSGG
NFWW--KRGYGGRGSS--------SR-------------------------GDGPGYS-S
RGGYGSGGPE----Y---------GNQGGGYGSG----G-RRYNGYNKGGNFG-------
---GGNYNDFGNYSEP-------MRGG-SFGGKSSG----S----GYGSGG---------
GS-GGYGQRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------------------IKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFDFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREVS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRNYFE
KY---GKIETIEVMEDRQGGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----INR
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYDGG--G--PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGAPHPTR-------------RQGEEGHDAKEPEQLRKLFIA-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMT--DSQT---KRSRGFGFVTYSC---VKEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKN IFVGGIKENTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFND-HDTADKIFVQ--KYHT----ING
HNCDVKKALSKQEMQSA-GSQRGRGGGSGNF-MG--------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------NPYGGGYGSGG----GN---
---GGYGSRRFLKQQKRA-------------------------TTLRR---RESKELSGK
LQVTLRQ-----------------------LPQMH-------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGR-------------------------------------SC-LLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KHSRGFGFVTYSC---VEEVD
AAMCAGPQKVDGR VVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIQVMEDWKSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----IYR
HNCEVKRALSKQEMQSA-GSHRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGD--NGFGG-DGGNYGGV-----L
RGGYGGGEP--G--Y--------G-NQGGGYGGG----G-GGYDGYSEGGNFGG------
-----------------QSNYGPVKGG-SFGGRSSG----SPYGGGYGSG----------
DGSGGYGSRGFKN-TAEK-------------------------GYSS-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------------------MKIEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKK-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---TGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGHGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NSGG--RGGYGGGG--------GGSRGS--YGRGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYDGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTYR------------------
-----------------------LCGKIER--SPTK----RSRGFGFV--------TYSC
VEEVDAAMCVDGRVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQ--------RFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVNKALSKQEMQSA-GSQRGCGGGSGNF-MGR-GGN----------------FGRGG
NFGG--RGGYGGGG--------GGSRGS-YGGGD-GGY--NGFG--DGGNYGGGPGYS-S
RRGYGGGG-P-G--Y---------GNQGGGYGG----------------GNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSGG----GS---
---GGYGS-------RRA-------------------------TVLSR---RESEELSGK
LQVTLRQSN------------CKN------LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHYSKEPEQLRKLFIG-GLSF
ETAD--DSL----REHFEKWGTLTDCVVTR--DPQT---KRSRGFGFVTCSC---VEEVD
AAMCALPHK VDGRVVESKR-AISREDS-VKLGAHLTVKK IFVGGIKEDTE-EYKLRDYFE
KC---GKIETIEVMEDRQSGKK---REFAF-VTFGD-HDTVD-IIVQ--KYHT----ING
QNCEVKKALSKQVMQSA-GSQRGCGGGSGNF-MHR-GGN------FGGG---GGNFGRGG
NFGG--RGDYGG---G-----GGGSRGS--YGAADGGY--NGFGG-DGGNYSGGPGYT-S
RGGYAG-GGP-G--Y--------G-NQGGGYGG-----G-GGYDGYNKGGNFSSG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGS----------G
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------------------------------------MEVKLLPGVEKLFIG-GLSF
ETTD--DSL----REHLEKWGPLTDCVVMR--YPQT---KSSRGFGFMTHSC---VEEVD
A ATCTQPHRLK---------IVSREDS-IKPDAHLRVKKN FVGGIKEDTE-EYNLRDYFE
KY---GKIEAIEVMEDRQSGIK---RGFAF-ATFED-HDTVDNIVVQ--EYHT----ING
E-----KALSEQEMQSA-GSQRGCGGGSSNF-VGH-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS-Y-GGGDVGY--NGYGS-DSDNSGSGPGYS-S
RGAMVVM--D-Q--D---------MAQGGGYG-----GGGGGYDGYNEGGNL--------
------FNDFGNHSG---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------TEVKRPPGRPQPDSSCRC------H--HRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REYFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYTC---VEEVD
AAMCAQPHKVDGHVVE PKR-AVSRDDS-IKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETI-VMEDRHSGKK---RGFAF-VTFDD-HDTVDKIV---------------
HNCEVKKALSKQEMQS-AASQRGRGGVSGNF-MGR-GRN------FGGG---GGNFGRGG
NFGG--RGGYGHGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP-G--Y--------G-NQGGGYGGG----G-GGYDGYNERGNFG-G----N
CGGGRSYNDFGNYSGQQQSNYGPMKGG-SFGGRSLA----SPYGGGYGSG----------
GGNGGCGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------MR--YPQT---KSSRGFGFMT-------EEVD
AATYTQPHR--T---------VSKEDS-IKPDAHLTVKKNFVGGTKEDTE-EYNLRDYFE
KY---GNIEAIEVMQDRQSGKK---RGFAF-ATFDD-HDTVDNIVVQ--EYH----TTNG
HNCE---------MQSA-GSQRGCGGGFGNF-MGC-GGN------FGGG---GGNFSRGG
NFGG--RGGYGGGGGG--------SRGS--YGGGDGGY--NGFGG-DGDNSGSGPGYS-S
RGGYGGDRPG----Y---------GPR---------------------WRKFGGGN----
YSGGGNYNDFGNYSGQQYSNYAPIFCG-RSSSHRLR----N----NPGGG----------
--------------------------SIFL-NSLPVF-----------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------MR--DPQT---KCSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVEPKT-EVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDRVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCRGGSGNI-MGR-GGN------FGGG---GDTFGCDG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGHPGYS-S
RGGCGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGG------
----GNYNDFGNYSGQQQSNYGPMKG-DSFGGRGSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVTPPPGCPQPDSSQ------------------------RLRKLFIG-GLSF
ETTD--DRL----REHFEKW----DCVVMR--DPQT---KRSRGFGFVTYSC---VEEVG
AAVC APPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVEK VFVDGVKEDTE-EYNLKDCFE
KY---GKIETIEAMEDRQ--------RFAF-VTFGD-HDTVDKIVVQ--KYH----TING
HDCEVKKTLSKQEMQSA-GSQRGRGGGSGNF-GGG-RGN------FGR----------GV
NFGG--RGGCVGGGGG--------SRGS--YGGGDGGD--NGFGG-DGGNYGGGY-----
GGG----GPG----Y---------GNQ-----------------------GGGCGN----
YGGGGNYNDFGNYSGQH-E-----RG--SSGGRSSG----SPYGGAYGSRC---------
IPSRGMGSQSPF------LHQGK--MLIHYQK----------------------------
--------PHRVLKPAR-------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------EEGHDPKEPEQLRGLSE------
--TT--EDS----REH-LKMSTLTDCVVMR--DPQK----RSRGF-FVTYSC---VEEVD
AAMCARPHKVDGRVVQPKR-AVSREDS-VKP-AHLTVKKIFVGGIKEDT--EYNLRDYFE
KY---GKIETIEVMEDRQSGKR----GFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HN CEVKKALSKQEMQSA-GSR-GRGGGSGNF-MGR-GGN------FGGG----GNFGCGG
NFGG--RGGYGGGG--------GDSRGS-Y------------------------------
---------------------------------------GGGYDGYNEGGNFGGV----N
YGG GGNYNDFGNYSGQ-QSNYGPMKGG-SFGGRSSG----SPYGGGYGPGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------KQSPSLPQPNSGHHH--------CHLGMEGYDPKEAEQLRKLFIG-G-SF
ETMD--DSL----REHC----TLTDCVVMR--DPQA---KCSRHFGFVTYSC---VEEVH
AKMCARPHKVDGRVVEPKR-AISRQDS-IKPGAHLTMKKIFVGDIKEDKE-EYNLRDYFE
KY---GETETIEIIEDRQRRKK------RI-CIHDDDHDTVDKLVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGHGGGSGNL-VDH-GGN------FEGS---GGNFGCGG
NFGR--Q-DYGGGG--------GGSRGG-F-GGGDGGY--NEFGG-DGGNCGGGPGYS-S
RGDYGDGG-P-G--Y---------GYQGGGYV-----CGGGGYDGYNVGGSFG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------DRSGSCR------RRSGLKMEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP---GGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPASRLQPDSSH---------RRCWGEEGHDPKEPEQLRKLFIG-GLTF
ETTD--DSL----REHFEKWGTLTDCVIMR--DPQT---KRSRGFGFVTFSC---AEEVD
AAM CAWPHKVDGRVVEPKR-AISREDF-VKP-----VKKIFAGGSK EDTE-EYNLRDYFE
KF---GKIETIEVMEDRQSRKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHS----ING
HNCEVKKALSKQGMQSA-GSQRGHGGGSDNF-MGR-GGN------FGGG---GGNFGPGG
NFGG--RGGYGGGD--------GGNRSS--YGGGDG---YNGFGG-YGGNYGGDPGYS-S
RGGYGGGGP--G--Y--------G-NQGGGYGGG---GG-GGYDSYNEGGNFGGG----N
YGG-GNYNDFGNYDGQQQSNYGPMKGG-SFGGRSSS----SPYGGG--------------
-GSGGYGSRRFKKKQQKR-------------------------ATVLS--RRESEEVSGK
LQVTLDSCPKCIRGT-----------IK-IYHRRSD----------DP------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------LCGN-ER--PPNK----MVQGLWF-------------
-CD--------LFLLEPKR-AVSREDS-VKPGAHLTVKKIFLGGITEDTK-EYNLRDYFE
KY---GKIETIEVMQERQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSRTGRGGGSGNF-MGC-GGS------NFGR---G------G
NFGG--RGGYGGGG--------GGSRGS-YGGGD-GGY--NGFGS-DGGNYAGGPGYS-S
RGGYGGGG-P-G--Y---------GNQ-------------GGYDGYNEGGNFGGG----N
Y GGGGNYNDFRNYSGQQQSNYGPMKGG-SFGGRSSA----SPYGGGYASSG----GS---
---GGYGSR-----RNCK-------------------------NLPQK---E--------
-----------------------------------G------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------LSQKLIQLGPI-------------LNSSWKRRGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AISREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGHGG
NFGG--RGGYGGG---------GGSRGS--YGGGDGGY--NGFGG-DGRNYGGGPGYC-S
RGGYGGG-----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGG-GP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------PGRPQPDSGRRR--------RRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVE PKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVAI--YWNW----N-E
HNSTYKALIVVEETVFP-SVKMKA----IDFNIKT-GFT------FLLASILV-LFT---
--------TCQQ-------------------AAFIMFS--CHLTF-LGGNYGGGPGYS-S
RGGYGGG--P-G--Y---------GNQGGGYG-----GGGGGYDGYNEGGNFGGG----N
YGG-GNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGGLQPDSGRR--------RHRRGEEGHDPKEQEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGSVTYSY---VEEVD
AAM CAGPHKVDGRVVEPKR-AVSREDS-VKPGAHLT VKKIFVG-----------------
-V---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEAKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGHGG
NFGE--E-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------MR--DPQT---KRSRGFDFVTYSC---VEEVD
AAMCAGPHKVDGRVVEPKR-AVSREDS-VKPGAHLTGKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIAVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGRSGNF-MGP-GGN------FGGG---GGNFGLGG
NFGG--RGGYGGAG--------GGSRGS--YGGGDGEY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP--G--Y--------G-NQGGGYGGG----G-GGYDGYKEGGNVGGG----N
YG--------------KQSNYGPRKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRSF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------------MEPDSGHRH------RR--SWQEGHDPKEPERLRELFIG-GLNF
ETTD--DSL----REHFEKWGILTDCVVMR--DPQT---KHSRGFGFVIYSR---IEEVD
AAMC-----VDG HVVEPKS-CFQREDY-LKSDAHLTVKK IFVGGITEDTE-EYNLRDYFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VIFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKVLSKQEMQSA-GSQRGRGGGSGNF-MGH-GVN------FGGG---GGNFGGGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGS-DSGNYGGGPGYC-S
RGGYGGGGP--G--Y--------G-NQGGEYGSG----G-GGYDGYNEGGNFGSR----N
HGGGGNYNDFENYSGQQQSNYGPMKGG-SFGGRSSG----SPCGSGYGSG----------
GGRGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------L------------------------------------
-CEVDAAMCVDGCAVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDFFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDE-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGS--------------------------------
-------------G--------GGSRGS-YGGGA-GGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG-P-G--Y---------GNQGGGYGG-----DGGRYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMNGD-SSGGRSSG----SPYGGGYGSGG----GS---
---GGYGSRRFEKQQKRA-------------------------TVLSR---GEREELSGK
LQLTLRQ-N------------CKN------LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

-------LSQKLIQLG-------PI------LNSSWKRRGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AISREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGHGG
NFGG--RGGYGGG---------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYC-S
RGGYGGG-----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPKQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DRQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVFREDA-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETTKVMEDRQSGKK---REFAF-VTFYD-HDTVDKI-VQ--KYHT----ING
HNCEVKKAFSKQEMQSA-G----S------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------LI------LNSSWKRRGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLRELRNGEIEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGGG---GG-GGYDGYNEGGNFGGGNY---
-GV-GNYNDFGNYSEQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLVIG-GLSF
ETTD--DSL----REHFEKWGTLTDRVVMR--DPQT---KRPRSFGFVTYSC---VEKVD
AA MCARPHKADGHVVEPKT-AVSREDS-IKPGAHLAVKK IFVGGIKEDME-EYNLRDYFE
KH---GKIETIEVMEDRQSGKK---RICF-----------FDKIVDQ--TYHT----ING
HDCEVKKALSKQEMWSA-GSQRGRGGGSGNF-MGR-RG----------------NCGRGG
NFGG--SGGCGGGG--------GGSRGG--YGGGDGGY--GGFG--DGGNYGGGPGYS-S
RGGYGGGGP--G--Y--------G-NQGGGCGGG----G-GGYDGYNEGGDFGGG----N
YGG-GNCNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGAEGSKNSRQGL-------------------------QFLAG--ERA-------
-RGCQESCR---------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRTQPDSSRRRRRHR--------EEGHDPKEPKQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDA-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
MY---GKIETTEVMEDRQSGKK---REFAF-VTFYD-HDTVDKIV-Q--KYH----TING
HNCEVKKAFSKQEMQSA-GSQRGRGGGSGNF-MGL-RGN------FGGG---GGNFGPGG
NSGG--RRGYGG-GG------------G--SK-RKLVF--LHFTA-SRECPHFLT-----
RGHLPTSKPE----M---------ASQVSHC--I----TLTHTQLPPSPTIKRPLV----
ITLGPAR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------MDRLGTRVGR------GESGLKMEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHCEKWGTLTDCVVMR--DPQT---RRSR GL------------EVD
AAMCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKKS FVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMENRQSGKK---RGFAL-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGP-GFG------RKRP---R-ELGVA-
---I--QSACGG------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------GRNHRPTGRLQSSKTRSGWRPGREPGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDRVVMR--DPQT---KRSRGFGFVTCSG---VEEVD
AA VCARPHEVDGPVS--------REDS-VKPGAHLTVKK IFVGGVKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFG--HDTVNKIVVQ--KYHT----ING
HNREVKKALSKQEMQSA-GPQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGLGG-DGGNHGGGPGFS-S
RGGYGG-GGP-G--Y--------G-NQGGGCGG-----G-RRYDGCNEGGNFGGG----N
YGDGGNDNDFGNYSGQQQSNYGPVKGG-SFGGRSLG----SLYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------IEVKLMPRRPQLDSGCHC------CR-------RGRREPEQLRKQFFG-GLSF
ETTD--DSL----REHFEKWD------------PQT---KRSRGFGFVTYSC---VEEVA
TAMCARPHRLMAR-------------------CPSTVKKIFVGGIKEDTE-KYNLRDCFE
KY---GKIETIEVMEDRQSGKR---RGFGF-VTFFFFLVFFDKIVVQ--KYHT----ING
HNCEVKKARSKQEMQSA-GSQRGHGGGSGNF-VGR-GGN------FGGD---KGNFGRSG
NFGG--RGGYGGGG--------GGSRGS-Y-GGGDGGY--DGFGG-DGGNYGGGPGYG-S
RGGYGGGG-P-G--Y---------GNQGGRYG-----GDGGGYDGYEEGGNFGGG----N
YGGRGNYHDFGNYSGQQQSNYRPMEGG-SFGGRSSG----SPYGGGYGTGG----GS---
---GGYGSRWF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKLPPSS---------------------------PKPAQLRKLFTG-GLSF
ETTN--GSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSY---VEEVD
AA MCARPHKVDRCVVEPKR-AVSREDS-VKPGLHLGVKK LFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VTFDD-HDRVDKIDVQ--KYHT----ING
HNCEGW-GLSKQEMQSA-GSQRGHGGGSGNF-MGR-GGS------FGGG---EGNLGCDG
SFGG--RGGYGGGG--------GGSRSS--YGGDDGGY--NGFG-----AYGSGRGFS-S
RWGYGGGGP--G--Y--------A-NQGGGYSGS----G-GGYDGYNEGKIFGSD----N
YGGVGNYNDFGNYSGQQQSNYGTMKGG-SFGGRSLG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------EFVGPI------LNSSWKRRGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVV-------------------------------D
AAVCARPHKVDGRVAEPKR-DVSRGDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSPGR----GFAF-VRFDD-HDTTDKIVV Q--KYLT----ING
HNCEVKKALSKQELQSA-GSQRCRGGGSGSF-MGR-GGN------FGGG---GGNFGHGG
NFGG--R-----------------------------------------------------
----------------------------------------GGYDGYNHGGDFGGG----N
H GGGGNYNGFGNYGGQQQSNYGAMKGG-SFGGRSSG----SPCGGGS-------------
---GGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------M------IFICQLKEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSS----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MKVKPPPGRPQPDSSGSR---------RRGEEGHDPKESEQLRKPFTG-GLTH
S----------------EKWGTLTDCVVMR--DPQT---NRSRVFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-PVSGEGS-VKPGAHLTVKT IFVGGIEEDTE-ECNLRDYVE
KY---GKIETTEVLEDGQSGQK---RGFAF-VTFDD-HDTVDKIVVQ--QYHT----VNG
QNGEVQKALSKQEMHSA-GSQRGRGGGSGNF-MGR-AGS------FGGG---GGNFGRVG
NFGG--RGCYGGGG--------GGSRGS--YGGGDGGY--NGSGG-DGGNYGGGPGYR-S
RGGYGGGGP--G--C--------G-NRGGGHGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSSRL-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPP--GAPHPT-----------RRQGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----RKHFEKWGTLTDCVVMT--DSQT---KRSRGFGFVTYSC---VKEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKN IFVGGIKENTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFND-HDTADKIFVQ--KYHT----ING
HNCDVKKALSKQEMQS-AGSQRGRGGGSGNF-MGH-GGN------FGSG---GGNFGCGG
NFGG--RGGYGGGG--------G----------GN------------GGNYGGGPVYS-S
KGAYGGG-GP-G--Y--------G-NQG----------G-GGYDGYHEGRNVGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMNGG-SFGRRSSG----NPYGGGYGSG----------
GGNGGYGDRRSAYRGPTP-------------------------APVSEFP----------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------------SYGERGKRK------NFLILCRISHDPKEREQLRKLFIG-GLSF
ETTD--DSL----REQFEKWDTLTDCVAMR--DPQT---KRSRGFGFVI--C---VEEVN
ATMCA--HKVD GCVVEPKR-AVSREDS-VKPGAHLPVKK IFVCGIKEDIE-EYNLRDYFE
KY---GKIKNIEVMEYRQSGKK---RGFAF-VTFDD-HDIVDKIVVQ--KYHT----IDG
HNCEMKKALFTQEMQF-AGSQRGRGGGSGNF-MGC-GGN------FGGG---GGNFGHGG
NFGG--RGGYGDGG--------GGSRDS--YGGGDG----------DGGNYGGGPGYS-S
RGGYDGG----G--Y--------G-NQGVRYGG-----G-GGYDDYNEGGNFGGG----N
YG-GRNYNDFGNYSGQQQSNYGPMKRG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------EEGHDPKEREQLRKPFIG-GLSF
ETTD--DGL----REHFEKWGTLTDCVVMR--DPQT---KCSRGFGFVTYSC---VEEVD
AAMCARPHKVDG CVVEPKR-AVSREDF-VKSGTHLTVKK IFVGGIKEDT--EYNLRDYFE
KY---GKMESTEVMEDRQS--K---RGFAL-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEPYDGGYGS------GSRSC-RYGSRTF-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------------PQPDSGHRH------RR--RWQEGHDPKEPERLRELFIG-GLNF
ETTD--DSL----REHFEKWGILTDCVVMR--DPQT---KHSRGFGFVIYSC---VEEVD
AAMC-----VDG HVVEPKS-CFRREDY-LKSDAHLTVKK IFVGGITEDTE-EYNLRDYFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VIFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKVLSKQEMQSA-GSQRGRGGGSGNF-MGH-GVN------FGGG---GGNFGGGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGS-DSGNYGGGPGYS-S
RGGYGGGRP--G--Y--------G-NQGGEYGSG----G-GGYDGYNEGGNFGSR----N
HGGGGNYNDFENYSGQQQSNYGPMKGG-SFGGRSSG----SPCGSGYGSG----------
GGRGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------KP------PISGLKMEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDRVVMR--VPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLXDHFE
KY---SKIETIEVMEDRQSEKK---RGFAF-VTFDD-HDTVDKT--------S----MNG
HNCEVEKPISKQEMPSG-GGQSGCGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGTR--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGP---G--Y--------G-NQGGGDGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSD----------
GGSGGYGSRRFKKKTTEK-------------------------GYSS-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------------------------------EGHDPKEPEQLRKLFMG-GLSF
EITD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYTC---VEEVD
AAMC-----V DGRVAEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLTEYVE
KY---GKIETIEVMEDRQSEEK---RGFAF-VTFDD-HDTVDKIV---------------
-------ALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGCGG
NFGG--GGGYGGGG--------GGSRGS--HGGGDGGD--NGFGG-DGGNYGGILVTV-V
EEAMVVVD-Q-D--V--------E-TKVVDMVGG---GG-GGDDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRCSG----SPYGFGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------DALPPPWRMRS--HGGESGLK--------MEGHDPKEPEQLRKPFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KHSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKKS FVGGIKEDTE-EYNLREYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKSLSKQEMQSA-GSQRGRGGGSSNF-MGR-GGN------FGGG---GGNFGRDG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGP--GDGGNYGGGPSYS-S
RGGYGD-GGP-G--Y--------G-NQGGGYGGG----G-GGYGGYNEGGNFRGG----N
YGGGGNYNDFGNYSGQ--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------GVVMR--EPRT---KLSRGFGFVTSCC---VEEVD
AAMCARPHQADGRVVEPKR-AVSRADS-VKPGAHLTVKKIFVGSIKEDTE-EYNLRDYFL
KY---GKIETIEVMEDRQRGKK---RGFAF-VTFDD-HNTGDKI IVR--EYHI----VKW
-------------MQSA-GSQRGHGGGSGNF-MGR-RGD------FGGG---GGNFGNFG
NFGG--RGGYGGGG--------GSSRGS-YGGGD-GGY--IGFGG-DGGKYGGGPGYS-S
RGGY--------------------GNQGGGYGG-----GGRGYDGYSEGGNFGGG----N
Y GGGGNYSDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSGV----EV---
---VDMVAEGF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPP--GAPHPT-----------RRQGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMT--DSQT---KRSRGFGFVTYSC---VTEVD
AAM CAPPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKN IFVGGIKENTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFND-HDTADKIFVQ--KYHT----ING
HNCDVKKALSKQEMQS-AGSQRGRGGGSGNF-MGH-GGN------FGSG---GGNFGCGG
NFGG--RGGYGGGG--------GGRRCS--YGGGN------------GGNYGGGPVYS-S
KGAYGGG-GP-G--Y--------G-NQG----------G-GGYDGYHEGRNVGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMNGG-SFGRRSSG----NPYGGGYGSG----------
GGNGGYGSRRFLKQQKRA-------------------------TTLRRRES---KELSGK
LQVTLRQLPQMH------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKLWPGHPQPDSGHRRHRQG--------EEGRDPKEPGQLRKLFSG-GLSF
ETTD--DSL----REHFEKWGMLTDCVVMR--DPQT---KCSRGFGFVTYSC---VEEVD
AAMCAQPHKVDGR VVEPKR-AVSRKDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIDTIEVMEDRQSGKK---REFAF-VTFDD-HSTVDKIVFQ--KYHT----ING
HNCEVKRALSKQEIHSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGLGG
NFGG--RGGYGGGGG--------GS------RGGDGGY--NGFGG-DGGNYGSGPGYS-S
RGGYSG-SGP-R--Y--------G-NQGGRYGG-------GGYYGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQ------------HFGGRSSG----SPYGGGYGSG----------
GGSGRYGSRRFLKTTEKG-------------------------YSS--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPSGRPQPDSGRR---------HRQGEEGHDPKEPEQLRKLFID-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AA MCG-----DGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVIEDRQSGKK---RGFAF-VTFDD-HDTVDKI-VQ--KYHT----ING
HNCEVKKALSKQEMQS-AGSQRGRGRGSGNF-MGR-GGN------FGGG---GGNFGRRG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGG--GP-G--Y--------G-NQGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSV----------
VDMVAEGSKNSRKGLQFL-------------------------AGERGVVRKAAGYFETV
VPNALEDL----------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIA-GLSF
ETTD--DSL----REHFEKWGTLTDCLVMR--DPQT---KCSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVAEPKT-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKTLSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGV--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGCGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRSF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
---------------------------------PNK----TFQGLWFCEVDA--------
-AMCARPHKVDGHVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYSLRDCFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYLT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSRNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGCG-----------GGSRGS-YGGGD-GGD--NGFGG-DGGNYGSGPGYS-S
RGGYGGGG-P-G--Y---------GNQGGGYCG-----GGGGDDGYSKGGNFGGG----N
YGGGGNYNDFRNYR------------G-SFGGRSSG----SPCGVGYGSGG----GS---
---GGYGSR-----RA---------------------------TVLSR---RERKELSGK
LQVTLRRSS---------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGG---------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------PRLAPPPHVRLPTSRRRR-------AVSASRAGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGGP-G--Y--------G-NQGGGYGGG---GG-GGYDGYNEGGNFGG------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------------------------------QLRKLFIG-DLSF
ETTN--DSL----REHFEKRGTLTDCVVMR--DPQT---KRSRGFGFVTYSY---VEEVD
AAM CARPHKVDRCVVEPKR-AVSREDS-VKPGLHLRLKK LFVGGIKEDTE-EYNLRDYFE
KY---GNIETIEIMDDRQSGKK---RRFAF-VTFDE-HDTVDKIVVQ--KYH----TING
HNCEVVKAILAVMET---------------------------------------------
-------------------------------------L--VEEEV-MVVEVV--------
------------------------------------------------------------
------V-AE-------VVMEE-VMVD-I-------------------------------
---MDLEVMVVTM---------AVVLVLVVVITMVVVGTIMILEIIVDNSNQIMD-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------M-GH--
---T--HRL----CGNE--------RP-----PNKM---LQGLWF---------------
-SMCARPHKVDGCVVEPKR-AVSREDF-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVIEDRQSGKK---RGFAF-VTFDD-HDTVDKILVQ--KYH----TING
HNCEVKKPLSKQAMQSA-GSQRGCGDGSGGG--------------YGG------------
------------GGGG--------SRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGRGGPG----C---------GNQGGGYGGG----G-GGYDGYNEGGNFGHGN----
YGGGLM------------------KGG-SFGGRSSG----SPYDGGYGSGG---------
RS-GRYGSRR-------------ATV----------------------LSRRESKELSGK
LQVTLRQ------S----------NCKN--LPQKEQ------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG--G--PGY---------GNQGGGYGG----GG-N----------Y--------
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP--G-Y---------GNQ-GGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------IEVK-----------PLC-------RRPRGEEVQDPKEPEQLRKLFIG-YLSF
ETTD--DSL----KEHFEKWGTLTDCVVMI--DLLT---KHSRGFGFVTYSC---VEEVD
AAM CAWPHKVDGQVVEPKR-AVSREDS-VKPGAHLTVKKT FVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HNTVDKTVVQ--KYHT----IKG
HNCQVKKALSKQEMQSA-GSQRGRGGGSGNF-MCR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDDICMFEMCVL-DK------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLLIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYAC---VEEVD
EAM CARPHKVDGRAVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-PDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-EGN------FGGG---GGNLGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGSGPGYS-S
RGGYGGGP-----GY---------ENQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GG----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFQKWGTLTDCVVMR--DPQT---KHSRGFGFVTYSC---VEE VD
A--------VDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCGGGSGNF-MGR-RGN------FGG----GGNFGHGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGGS----G-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKE-GSFGGRSSG----SPYGGGYGSG----------
GGGGGYGSSRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGKFAGG
NYGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPSGRPQPDSGRRR--------RRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVV--FVKF----FK-
---------------IFLACLKGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGG--GP-G--Y--------G-NQGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGK--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPLSAQL--QPSLHHC-QR--------EESHDHKESEQLKKPFTG-GLSF
KTTD--DSL----REHYEKWGTLTDCVMRD--PPQT---KCSRGFGFVIYSC---VEEVN
-AMCAQPHKVDWCVVEPKK-AISREDS-IKPEDTEE----------------YNLRDYFE
KY---GKIETTEVMEDRQI----------------------DKTVVQ--KYH----IIKG
HNCEVKKALSKQEMQSA-GSQRGRGGGPGNF-MGCRGGS------FRDD---RDNFGRGR
SLGG--RGGYAGGGGG--------SKGG--YGGGDGGY--NGFGG-DCGNYGGGPGYS-S
RGGYGGGGPG----Y---------GNQGGRYSG-----S-RGYDGYNEGGNFGSGN----
YGGGGNYNDFGNYSGQQQSNYELMKGD-SFGGRSSG----SPHGGRYGSGG---------
GS-GRYSSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------SGR-GSSPTHSP------SESGLEMEGHNSKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWD------------PQT---KCSRGFGFVTYSC---VEEVD
AA MCARPYKVDGA--------VSREDS-VKPGAHLTVKK IFVSGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQ----------------------IDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQGGHGGGSGNF-MGH-GGN------FGGG---GGNFGRGG
NFGG--RGGYDGGG--------SGSR-G-Y-GGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG-P-G--Y---------GNQGGGYS-----GGGRGYDGYHEGGNFGG------
----GNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPCGGGYGSGG----GS---
---GGYGSGRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------KMEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDG CVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGD------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-----------------------------------------------------
-----------------QSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------L------------------------------------
-CEVDAAMC---------R-AVSREDS-VKPGAHLTMKKIFIGSIKEDTE-EYNLRDHFE
KC---GKIETIEVMEDRESGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKREMQSA-GSQRGCGGGSGNF-MCG-GGN----------------FVHSG
NFGG--RGGYGGGG--------GGSRGS-YRGGD-GGY--NGFGR-DDGNYGGGPGYS-S
RGGYGGGG-P-G--Y---------GNQGGGYGG------GGGYDGYNEGGIFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKWG-SFGGRSSG----SPYGGGYGSDG----GS---
---GGYGS-------RRA-------------------------TVLSR---RESEELSGK
LQW-----N------------CKN------LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------------RCRQGEEKLFTG-GLSF
ETTN--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSY---VEEVD
AA MCARPHKVDRCIVEPKR-AVSREDS-VKPGLHLGVKK LFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VTFDD-HDRVDKIDVQ--KYHT----ING
HNCEGW-GLSKQEMQSA-GSQRGHGGGSGNF-MGR-GGN------SGGG---EGNFGCDG
SFGG--RGGYGGGG--------GGSRSS--YGGDDGGY--NGFGG-DGGSYGSGPGFS-S
RRGYGGGGP--G--Y--------A-NQGGGYSGG----G-GGYDGYNEGKIFGSD----N
YGGVGNYNDFGNYSGQQQSNYGTMKGG-SFGGRSLG----SPYGGGYGSG----------
GRSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------------MQQLRKLFIGGGLSF
ETTD--DSLR----EHFEKRGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-QYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGG-G---PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRNSG----SPYGGGYGSG----------
GGNGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-----------------------------------------VVQPWLTTSSASGFTPFSC
LSLLSSWDYRKCLVVEPKR-AVSRQDS-VKPVAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDIIDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGHGGGSGNF-MGC-RGN------FGGA---GGNFGLGG
NFGG--RGGYGGGG--------GGSRGS-YGRGD-GGY--NRFGR-DGGNYGGGPGYS-S
RGGYGGGG-T-G--Y---------GNQGGAYGG-----GGEGYDGYNEGGNFGGG----N
YGGGGNYNDFGNHSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSGG----GS---
---GGYGSR-----RF--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVESLTGRPQPGSGRRF--------RRRGEEGHYSKEPEQLRKLFIG-GLSF
ETAD--DSL----REHFEKWGTLTDCVVTR--DPQT---KRSRGFGFVTCSC---VEEVD
AAMCALPHK VDGRVVESKR-AISREDS-VKLGAHLTVKKIFVG-------------DYFE
KC---GKIETIEVMEDRQSGKK---REFAF-VTFGD-HDTVDII-VQ--KYHT----ING
QNCEVKKALSKQVMQS-AGSQRGCGGGSGNF-MHR-GGN------FGGG---GGNFGRGG
NFGG--RGDYGGGG--------GGSRGS--YGAADGGY--NGFGG-DGGNYSGGPGYT-S
RGGYAGG-GP-G--Y--------G-NQGGGYGG-----G-GGYDGYNKGGNFSSG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKLLPGCPQPDSGR----------HRRGEEDHNPKEPEQLRKLFTI-GLSF
ETTD--DRL----RDHFEKWGTLTDCV--------------------------------D
AAMCARPHKVDGRVVEPKK-AVSRKDS-VKPGAHLTVKTIFVGGIKEDTE-ECNLRDYFE
KY---GKIETIEVMEDRQSGKK---KGFAF-VTFDD-HDTVDKIIVQ--KYQT----ING
HNCEVKKALSKQEMQSS-GSQRGRGGGSGNF-MGR-RGN------FGGG---GGGSFGGR
NSGS----PYGGGY--------GS-------GGG--------------------------
---------------------------------------SGGY---------GGR----R
F-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------LLVTPAPGDPTLYSHLPR-----------GESGFK------------------
-----------------------MEGHDPK--EPEQLRKLFISGLSFETTDD------SL
REHFEKWGILAD-CVWNQR-AVSRKDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIQ-------RQSGKK---RGFAF-VTSDD-HDTVDKIAVQ--KYHI----ING
HNCGVKKALSKQEMQSA-GSQRGQEGGSGNF-MGR-GVD------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS-YGGSD-SGY--NGFGG-DGGNYGSSPGYS-S
RGGYGGGG-P-G--Y---------GNQGGGCGG------GRRYDGCNEGGNFGGG----N
YGDGGNDNDFGNYSGQQQSNYGPVKGG-SFGGRSLG----SLYGGGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------MAAIKEEREVEDYKRKGRRSS--------QGHEPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMSARPHKVDG RVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLREYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQTA-SSQRGRGGGSGNF-MGR--GN------FGGG---GGNFGRGG
NFGG--RGGYGGGG-G-----GGGSRGS--FGGGDG-Y--NGFGD--GGNYGGGPGYG-S
RGGYGGGGGP-G--Y--------G-NPGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSG----SPYGGGYGSG----------
SGSGGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------------------------------MDQEGHDPKEPEQLRKLFIG-GLSF
ETT---G------------DSTLTDCVVMR--HPQT---KRSSGFGFVTYSC---VEKVD
AAMCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKTIFVGGIKEDME-EYNLRGYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ISG
HNCEVKKAFSKQEMQSA-GSQRGRGGGSGNF-MGR-G---------------GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGEY--NGFGD--GGNYGGGPGYS-S
RGGYGGGGPG-G--Y--------G-NQGGGYGGG----G-GEYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPLPGHPQPNSSRRS-GQG--------EEGHDPNEPEQLRKLLIG-GLSC
ETT----DL----REHFEKWDTLTDCVVMR--DPQT---KRSRSFQFVTYSC---VEEVD
ATMCARPHKVDGHLVEPKR-AVSTEDS-VKP-----VKK IFVGGIKEETE-KYNLRDCFE
KY---GKIESIEVMEDRQNGKK---RRFAF-LTLND-HDTADNIFVQ--KYH----TNNG
HNCELKKALSKQEMQSA-GSQRGRGRGSGNF-TGC-GGN------FGGD---ADNFGCGG
NWWK--RRLW--------------------------------------------------
------------------------------------------------------------
--------------------WWTWWQQ-SFGGRSLG----SPYGVGTG--V---------
GS-GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGYDPKEPEQLRKLFIG-----
---D--DSL----REHFEKWDTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CAQPHKIDGSVVAPKR-AVSREGS-IKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFVF-VTFDD-HDTVDKIVVQ--KYLT----ING
HNCEVKKALSKQEMQSR-----GRGGGSGNF-MGC-GGN------FGDG---GGNFGCSG
NFGG--RDGYGGGG--------GGSRDS-Y-GGGDVEI--MDLEV-M------VATMAVS
RGGYGCGE-P-G--Y---------GNQGGGYA-----GGGGGDDGYSKGGNFGGG----N
YGGGGNY-DFGNYSGQQQSNYGLMKGG-SFGGRSSG----SPYGGGDGSGG----GS---
---DGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGCR--------RRRRREEGHDPKEPEQLRKLFIG-GLSF
ETTD--DRLR----EHFEKWGTLTDCVVMR--DPQT---KRSRDFGFVTYSC---VEEVD
AAMC ARPLKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RAFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGSGSGNF-MGH-GGN------FGGG---GGNFGCGG
NFGG--RGGYGG----------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-G---PGY---------GNQGGGYGG----GG-GGYDGYNEGGHFGGNY----
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---IEEVN
AAM CARPHKVDGRVVEPKR-AVSREDSRVKPGAHLTVKK IFLGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----INR
QNCEVKKALSKQEMQSA-GSQRGRGRGSGNF-MGR-GGN------FGGG---GGNFG---
---G--RGGYGG---G-----GGGSRGG--YRGGDGGY--NGFGG-DGGNCGSG-PYS-S
RGGYGG-GGP-G--Y--------G-NQGGGYGG-----G-GGYDGYNEGGNFGGGNY---
GGGGGNYNDFGNYSGQQQSNYRPMKGG-SFAGRSSG----SPYGGGYGSG----------
GGSGGYGSRGF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------MSPGHDSKEPELLQKLFIG-GLSF
KTTD--D-----------------NCVVM---RPQK---TRSRGFAFVTYSC---VEEVE
AARCARPHKADRCVVGPKR-AVSIEDS-VKSGAHLTARKIFVGGIKEETE-EYNLRDYFE
KY---GKIETAEVMEDRQSGKK---TGFAF-ITFDD-HDTVDKIVVQ--KY HS----ING
HNCEVKKALSKQEI---------------------------------------GSFGCGG
NSDG--RGGYGGEG--------GGSRGS-YGRGD-GGY--NGFGG-DGGNYGGSPGYS-S
RGGYDGDG-P-R--I---------W-----------------W---CEGGNFGGG----N
Y GGGGNYNDFGNYSEQQQSNYEPMKGG-TFGGRSSG----IPHG------G----ES---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------MAAIKEDREVEDYKRKGRRSSQQKYRRLNKGHEPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMSARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLREYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQTA-SSQRGRGGGSGNF-MGR--GN------FGGG---GGNFGRGG
NFGG--RGGYGGGG-G-----GGGSRGS--FGGGDG-Y--NGFGD--GGNYGGGPGYG-S
RGGYGGGGGP-G--Y--------G-NPGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSG----SPYGGGYGSG----------
SGSGGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------MAAIKEEREVEDYKRKGRRS--------SQGHEPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMSARPHKVDGRVVE PKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLREYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQTA-SSQRGRGGGSGNF-MGR--GN------FGGG---GGNFGRGG
NFGG--RGGYGGGG-G-----GGGSRGS--FGGGDG-Y--NGFGDVKGGNYGGGPGYG-S
RGGYGGGGGP-G--Y--------G-NPGGGYGGG----G-GGYDGYNEGGNFGGGTKC-N
YGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSG----SPYGGKYISVQKNPCGYGSG
SGSGGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVE PKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGG---------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGGGGPGGY---------GNQGGGYG------G-GGYDGYNEGGNFGG-NY---
-GGGGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEAKLLPS---------------RGHRCWGEEGHDPKEPEQLRKLLMG-GLSF
ETPG--DSL----REHSEKWGTLTDCVVMR--DSQT---HRSRGFGFVTYSW---VEEVD
AA TC-----VDGRVVEPER-AASREDS-VKPAAHLTVKKM FVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VSFDD-HDTVGNIVVQ--KSHT----ING
PNCEVEKTLYEQEMQSA-GSQRGPGGGSGNF-MGR-GGN------FGGG---GGDFGRGG
NSGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGG------
--G-YGGGGP-G--Y--------G-NQGGGYGS-----G-GGYDGYNEGGNFGSG----N
YGGGGNYNDFGNYSGQQQSNCEPMKGG-SFGGRSSR----SPSGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------M-GH--
---T--YRL----CDNE--------RA-----PNKT---FQRLCFCDPENSR---VEEVD
AALCAWPHKVDGHVVEPKR-TVSREDS-VKPGAHLTVKKIFVGGIKEDME-VYNLRDYFE
KY---GKIETIEVIEARQSGKK---RGFSF-VTFDD-HDTVDNVVVQ--KDH----TING
HNCEVKKALSKQEMQSA-GSQRGRGGRSGNF-MGR-GGK------LGDG---GGNFGRR-
-------GGYCSGGGG--------SRGS--YGSGDGRY--NGLGG-DGGNYGSGPGYS-S
RGDYGGGGPG----Y---------GNQGGRCGGG----G-RGYDGYSEGGNFGGGN----
YGGGGNY------SGQQQSNYGPMKEG-SFGGRSSG----NPYGGGYGSGG---------
GS-GGYASRRFL------NKTETATV----------------------LSRRESEVLSGK
LQVTLSQSSQISLE----------NCKN--LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

------------MARNTKPSPGRKL------GKSGLKMEGHDTKEPEQLRKLFIG-GLSF
ETTD--S--------------TLTDWVVMR--DPQT---KCSRGFGFVTYSC---VNKVD
AAMCAQPHKVDGCVVEPKR-AVSREDS-VKPDTHLT--KIFIGGMKEDTE-EYSLRDYFE
KC---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKTVVQ--NYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCGGGSGNL-MGR-RGN------SGGG---GGNFGHGG
NFGG--RGGCGGGG--------GGGRGS-Y-GGGDGGY--NGVEG-DGGNYGGGPGYS-S
RGGYGGGG-P-G--Y---------GNQGV------------VEDGYNEEGNFSSD----N
YGGGGNWVSF--------------------GGRSLG----SPFGGGYGSGD----GS---
---GGCGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------SSSH-------QC-H--------HHGGEEGHDPNEPEQLRKLSVG-DLSC
ETTD--DHL----RKHLEKWGTLTDCVVMK--DSQT---KRSRDFGFVTYSC---VEEME
AAMCARPQK VDGHVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDIE-EYNLRNYFE
KY---GKIETMEVMEDRQ------------------------------------------
------------KMRFA-GSQRGRGSGSGNF-MGR-RGN------FGGG---GDNFGCGG
NFDG--RGHYGGRG--------GGSRGS-YEGGD-GGY--NTLGD-DGGNYGSGLGYS-S
RGGYGGGE-P-G--Y---------GNLGGGYGD-----GGGGHDGYNEGGNFGSG----N
YGDDGNYNNFGNYSGQQQSNYEPMKEG-SFSGRSSG----SSCSGGYGSGS----ES---
---DEYDSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGCPQPDSSRR---------CRQEEEGHDPKEPEQLRELFIG-GMSF
ETTD--ANL----REHFEKWGILTDCVVMR--DLQT---KRSRDFGFVTYSC---VEEVD
AAMCALPHK TDGRVVEPKR-VVSREDL-VKPSAH-TVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKTETIKVMEDKQSAKKKKIRGFAF-VTFDD-HDTVDKIVVQ--KYHN----ING
HSCEVRKTLSKQEMWSA-GSPRGR-GGSGNF-MGH-GGN------FGGG---GGNFGHGG
NSGY--GNQ-GGGY-----------------GGG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------GHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------MLEGHDPKEPEQLRKLFIG-DLSF
ETTD--DSLR----EYFEKWGTLTDCVVMR--DAQT---KRSRGFGFVAYSC---VTEVD
AA MCARPCKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGSIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAS-VTFDD-HDTVDKTVVQ--KYHT----ING
HNCEVKKAFAKQVMQSA-GSQRGRGGGSGNF-MGC-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGSGPCYS-S
RGGYGGGG----PGY---------GNQSGGYGG----GV-GGYDGYNEGGNVDGGNY---
-GGGGKYNDFGNYSGQQQSSYGPMKG-GSFGGRSLG----SPYGGGYGSG----------
SGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRRRRRRG--------EEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HSCEVKKALSKQEMQSAAGSPRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGSFFIII--------LGSPGS--CCSFDCIL--PGFA-VLGGNYGGGPGYS-S
RGGY-G-GGP-G--Y--------G-NQGGGYGG-----G-GGYDGYNEGGNFGG------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPLAQLAPSPT-----------RRQGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMT--DFQT---KRSRGFGFVTYSC---VKEVD
AAM CTRPHKVDGRVVEPKR-AVSREDS-GKPGAHLTVKN IFVGGIKENTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFND-HDTADKIVVQ--KYHT----ING
HNCDVKKALSKQEMQS-AGSQRGRGGGSGNF-MGH-GGN------FGSG---GGNFGCGG
NFGG--RGGYGGG--------------------GN------------GGNYGGGPVYS-S
RGAYGGG-GP-E--Y--------G-NQG----------G-GGYDGYHEGGNVGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMNGG-SFGRRSSG----SPYGGGYGSG----------
GGNGGYGSRRFLKQQKRA-------------------------TTLRRRES---EELSGK
LQVTLRQLLQMH------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------VV--RPWL---TTSSASGFTPFSC---LSLLS
SW-----DYRKCLVVEPKR-AVSREDS-VMPVAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDIIDKIVVQ--KYHT----TNG
HNCEVKKALSKQEMQSA-GSQRGHGGGSGNF-MGC-GGN------FGGA---GGNFGLGG
NFGG--RGGYGGGG--------GGSRGS--YGRGDGGY--NRFGR-DGGNYGGGPGYS-S
RGGYGGGGT--G--Y--------G-NQGGGY----------GYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPLPGHPQPNSSRHV---------GQGEEGHDPNEPEQLRKLFIG-GLSR
ETTD--DSL----REHFEKWGTWTDCVVMG--DPQT---KCSRGFDFVTYSC---VEEVD
AV MCAQPHKVDGHLVEPKR-AVSTEDS-VKSGA-LTVKK IFVGGIKEDIE-EYNLRAYFE
KY---GKIETTEVMEDRQSGKK---RRFAF-VTFND-HDTADKIV---------------
-------ALSKQEIQSA-GSQRGHGGGSVNL-TGC-GGN------FGDA---GDNFGCGG
NFGG--RGG--------------GSRGS-Y-GGGDGRY--NGLGG-EDGNYRGGPGYS-S
RGG-----------Y---------GNQGGGYG-----GGGGGYDGHNEGGNFGGG----N
YSGGGNYTDFGNYSGQQRSNYGPIKEG-SFGGGSSG----SPYGGGYGSGV----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------SREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGC-GGN------FGGG---GGNFGSGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS--
-------------RY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGNY----
-GGGGNYNDFGNYSGQQQSNYRPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------IEVKPLP-------GCPQ--------PTLAITGHDPNEPEQLRKLSIG-GLSC
ETTD--DRL----REHFEKWGTLTDCIVMK--DPQT---KCSRDFGFVIYSC---VEEVE
AAMCARPHKVDRHVVEPKR-AVSGEDS-VKPGAQLTVKKIFVGGIK-DIE-EYNLRNYFE
KY---GKIETIEVMEDRQ------------------------------------------
------------KMQFA-GSQRGRGSGSGNF-MGH-RGN------FGGG---GDNFGCGG
NFGG--RGHYGGGG--------GGSRGS-YEEGD-GGY--NTLGD-DGGNYGGGLCYS-S
RGGYGGGE-P-G--Y---------GNLGCGYGD-----GGGGHDGYNEGGNFGGG----N
YGDGGNYNNFGNYSGQQQSNYGPMKEG-SFSGRSSG----SSCSGGCGSGG----GS---
---DEYDSRKF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------I------LNSSWKRRGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVV-------------------------------D
AAVCARPHKVDGRVAEPKR-DVSRGDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSPGR----GFAF-VRFDD-HDTTDKIVV Q--KYLT----ING
HNCEVKKALSKQELQSA-GSQRCRGGGSGSF-MGR-GGN------FGGG---GGNFGHGG
NFGG--R-----------------------------------------------------
----------------------------------------GGYDGYNHGGDFGGG----N
H GGGGNYNGFGNYGGQQQSNYGAMKGG-SFGGRSSG----SPCGGGS-------------
---GGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFG-GNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------LEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWDTLTDCVVMR--DPQT---KHSRGFGFVTYTC---VEEVD
AAMCAQPHK VDGHVVDPKR-AVSREDS-VKPGTHFTVKKIFVG DT-----EEYNLRDYFE
KY---GKIETIKVMEHRQSGKR---RGFAF-VTFDD-HDTIDKIVVQ--KHHT----ING
YDCEVKKS--------A-GSQRGRGGGSGNF-MGR-GGI------FGGG---GGNFGRG-
--------DYGGGG--------GGSRGS-Y-GGGDGGY--NGFGG-DGGNYG--------
--GYGGGG-P-G--Y---------GNQGGGYG-----GGGGGYDGYNEGGNFGGG----N
YAGGGNYNDFRNYSGQHG------------------------------------------
----GYGTRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG-----G-GGYDGYNDEGGFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------------KELEQLKKLFIG-GLSF
ETRD--GSF----REYFKKWSTLTGCVIIR--DPQT---KCSTNSGFVTYSC---VEEVD
AA MCARPHKAR--AMEPKT-AVSRESS-VKASAHPTVKNRG VGGVEEDTE-EHNLRDYFE
KY---HKIETTEVTEDRQSGKK---RGFAC-VTFDD-HDK---IVVQ--KHSINRRE---
-----------------------------------------------VK---NGSFGLGR
NSGG--RGGYGA-GSG--------SRSS--YGGGVAGY--NGFEG-DGGNYHSCPGFD-S
KG-----GY-----------------GGGRYGGS----S-GGYDGYNEEGNLGSGNYG--
--GGRNYNDFGYY-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRIQPTPA----VAG--------GGGHDPKESEQMRKLFIG-GLSF
ETTD--D-------------------------NPQT---KRSRSFGFVTYSC---VEEVD
AAMCTQPHKID---------AVLREDS-VNPGAHLTLKKIFY------------------
-----GKIETIEVMEVRQSGRK---RGFAF-VTFDD-HDTVDEIV VQ--KYY----PISG
LNCEVKKALSKQEMLSA-GSQRGCGGGSGNF-MGC-GGN------FGRG---RGNFGRDG
NFNE--RGGYDGYNEG--------------------------------------------
------------------------------------------------------GN----
F GGGGSYNDFGNYSGQQQSNYRPMKGG-SFGGRSPG----CPYGGGYGSAG---------
GS-GGYGSRRFK------KKNKQEKRAIVLSRR-------------------E----SEE
LQVTLR------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------------------------------EGHDPKEPEQLRKLFIG-GLSF
ETTD--D-----------------NCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCA RPHKVDGRR------GVSREDS-VKPGVHLTVKK IFVGGIKEDTE-EHNLRDYFE
KY---GKIETIEVTKEWEK-------GF-----------------AF--KYH----TING
HNCEVKKALSKQEMQSA-GSRRGRGGGSGTF-MGR-GGN------CGGG---GGNFGRGG
NFGG--R-GYGGGGGG--------SRGN--YGGGDGG------------NYGGSPGYS-S
RGGYGGGGPG----Y---------GNQGGGY------------DGYNEGGNFGGGN----
CGGGGNYNDFGSYSGQQQLNYGPMKGG-SFGGRSSG----G----RS-------------
---GGYGSRRLK------KKKNNKKGLQFLAGETARSCQE--------------------
---------CCRLL----------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------IEVKPLPGHPQPDSGHLS---------------CCCGEEERLRKLFIG-GLSF
ETID--DNC----VVMR--------DS-----PNKM---FQGLWF---------------
-SMCARPHKVDGRVVEPKR-AISREDS-VKPGAHLTVKKIFAGGIKEGTE-EHNLRDYFE
KY---GKIETIEVMEDRQSGKK---KGFAF-VTFDD-HDTVDKIVVQ--KYH----TING
HNCES-----------D-GSQRDRGGGSGNF-MGR-GGN------FGRR---GVYGGGG-
--------------GG--------SRGS--Y-GGG--------DG-DGGSYGGGPGYS-S
RGGYGGGGPG----Y---------GNQGGGYGGG----G-GGYDVYNEGGNFGGGN----
YGGGGNYNDFGNYGGQQQSNYGPMKGR-SFGGRSSG----SPHGGGYGSGG---------
GS-GGYGSRRFK------KSR-----------------------------KG-----L--
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRGR------RRRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCAQPHKVDGR VVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---SKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQQMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGKYNDFGNYSGQQQSNYGPMKG-GSFGGSSSG----SPCGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKQPPGRPQPDSGR-R-------RRRRGEEGHDPKEPEQLRKLFIG-GLKH
FEK----------------WGTLTDCV-------------------------------VD
AAMCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NLGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP--G--Y--------G-NQGGGYGGS----G-GGYDGYNEGGNFG-G----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKLPPGRPQPDSGCRR--------CRREEEGHDPKEPKQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
TAM CARPHKVDGRAVEPKR-AVSREAA-VKPGAHLTVKK IFVGGIKEDTEEEYNLRDYFE
KY---GKIETTEVTEDRQSGKK----RICF-CNFYD-HDTVDKIVVQ--KYHT----ING
MS--------------A-GSQRGCGGGSGNF-MGR-GGN------FGGG---GGNFGCG-
--------GYGGGG--------GGSRGS-Y-GRGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGSGG-P-G--N---------GNQGGGYG-----GGGGGYDGYNEGGNFGGS----N
YGGGG-----------------------SFGGRSSG----SPCGGGYGSGG----RS---
---GEYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGCPQPDSGSRH--------RRWGEEGHDPKGPEH-----------F
ETTD--DSL----REHFEKWGTLTDCLVMR--DPQT---KRSRGFGFVTYSC---VTEVD
AAMRARPFKVDGR VVEPKR-AVSREDS-VKPGAHLTVKK IFVGSIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAS-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALAKQVMQPA-GSQRGRGGGSVNC-MGH-RGN------FGGG---GGNFGHDG
NFGG--RGGYGGGG--------GGSRGS--YGGGDVDI--MD------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------LCGN-KR--SSDK----TFQGLRF-------------
-SICARPHKVDGCVVEPKQ-AVYREDS-VKPGVHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIKVMEDRQSGKE---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALYKQEMQPA-GSQRGRGGGSGNF-MGC-GGN------FGGG---G------G
NF-G--RGGYGGGV--------GGSRGS-YGGSD-GGC--NGFGG-DGDNYDGSPGYS-S
RGGYGGGG-P-G--Y---------GNQGE----------GGGYDGYNEGGNFGGC----N
YDGGGNYNDFGNYSGQQQSNYGPIKGG-SFGGRSSG----SPYGGCYGPGG----GS---
---GGYGSR-----RKRA-------------------------TVLSR---RESKELSGK
LQVTLRQSN------------GKN------LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------WDTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AA MCAQPHKGDGRVVEPKR-AVSGEDS-AKPGAHLTMKKN FVGGIKEDTE-EYNLRDCFE
KYGKYGKMETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIALS--KQEM----Q-S
AGS---------------------------------------------------------
--------------------------------------------Q-RGRGGGSGNFMG-R
GGNFGGR--G-G--Y---------GNQGGGYG-----GGGGGYDGYNEGGNFGGG----N
YGGRGNYNDFGNYSGQQQP------RG-SFGGRSSG----SPYGGGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------PAPTSP--HTGKGTLKIR--------EGRDGRHGQEQLRKLFIG-SLT-
ETTG--DSL----REHFEKWGTFTGCVVIK--DPQT---KCSWGFGFVIYS C---VEERY
-----------------QR-AISREDS-AKSAAQLTAKK IFVGGIKEDIE-EYNLRDHFK
RY---GKTETTEVMEDWQIGK----RGFAF-VTFDD-HATVDKTVIQ--KYH----NING
HNWEVKEAHSIQEMWSA-GLQRGCGGGSGNF-MGG-GGN------SGGG---GSNFGCGR
NFGG--RRGYSGEAGG--------SRDS--YGGGAGGC--NGFGG-DGGTYDGGPGSS-G
RGGYGGGGPG----Y---------RNQGARYGG-------GGYDGYNEGGNFGGGACGGT
CGGGRNNNDSGNYSGRQQSNFGSMKGG-SFGGRSSG----SPYGGGYGSGG---------
GV-VDMVAEVF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGG----GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGG-GP---GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGCRR------RH--RREEGHDPKEPKQLRKLFIG-GLSF
ETTD--DSL----REHFEKWDTLTDCVVMR--DPQA---KRSRGFGFVTYSC---VEEVD
TAM CARPHKVDGHVVEPKR-AVSRKAA-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVTEDRQSGKK---RGFAF-VTFYD-HDTVDKIVVQ--KYHT----IN-
----VKKALSKQEMQS-AGSQRGCGGGSGNF-MGC-GGN------FGGS---GGNFGCGG
NSGG--RGGYDGGG--------GGSRGS------DGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG-GP-G--N--------G-NQGGGYGGG----G-GGYHGYNEGGNFGGS----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRRSG----SPYGSGYGSG----------
GRSGEDGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MKVKPPPGHPQPDSGSRR------RRRCRGEEGHDPKESEQLRKPFTG-GLTH
S----------------EKWGTLTDCVVMR--DPQT---NRSRVFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-PVSGEGS-VKPGAHLTVKT IFVGGIEEDTE-ECNLRDYVE
KY---GKIETTEVLEDGQSGQK---RGFAF-VTFDD-HDTVDKIVVQ--QYHT----VNG
QNGEVQKALSKQEMHSA-GSQRGRGGGSGNF-MGR-AAS------FGGG---GGNFGRVG
NSGG--RGCYGGGG--------GGSRGS--YGGGDGGY--NGSGG-DGGNYGGGPGYR-S
RGGYGGGGP--G--Y--------G-NRGGGHGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSSRL-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTYR------------------
-----------------------LCEV-D-------------------------------
AAMCAGPQKVDGRVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIQVMEDWKSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----IYR
HNCEVKRALSKQEMQSA-GSHRGRGGGSGNF-MGR-G----------------------G
NFGG--RGGYSGGG--------GGSRGS-YGGGD-GGD--NGFGG-DGGNYGGV-----L
RGGYGGGE-P-G--Y---------GNQGGGYGG-----GGGGYDGYSEGGNFGGV----T
M--------------VMQSNYGPVKGG-SFGGRSSG----SPYGGGYGSGD----GS---
---GGYGSR-----GFKN-------------------------TAEKA---RESEELSGK
LQVTLR------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPYKVDG RVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMRSA-GSQRDRGGGSGNF-MGR-GGN------FGGG---GG------
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------------------------------QGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFVFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGG---------GGSRGS--YGGGDGGY--NGFGG-D-GNYGGGPGYS-S
RGGYGGGGGG--PGY---------GNQGGGYGG-----G-GGYDGYNEGGNFGG-----G
NYGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------------------------------------------------GHTY
R-------L----CGDD--------RS-----PNKT---FQGLWF---------------
-SMCARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKKIFVGSIKEDTE-EYNLRDYFE
KY----------VMGDRQSRRK---RGFAF-VTFDD-HDTVDITVVQ--KYH----TMNG
HNCEVKK------MQSA-GSQRGHGGGSGNL-MGR-GGN------FGGG---GGNFGHG-
-------G-----KFG--------GRGG--YGGGG--------GG-DGGNYGGGPGYS-S
RGSYGGGGPG-G--N---------GNQGGRYCGG----G-GGYDGYNEGGNFG-GY----
YGGGGNYNDSGNYSGQQQSNYGPMKGG-SFGGRSSG----SPSGGGYGSGG---------
GS-GGYGSRRDT------VIS-----------------------------RR-----ERK
LKVTLRQ------S----------NYKN--LPQKE-------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGLRRPDSSSRC------HH--QGKEDHDPEEPEPLRKLFIG-GL--
--------------KHFEKWGTLTDCVVMR--DPHT---KRSRGFGFVTYSC---VEEVD
AAM CAGPHKVDGRVVEPER-AVSREDS-VKPGAHSTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSAKK---RGFDL-VTFDD-HDTVDKIVGQ--KYHI----ING
YNCEVKKALSKQEMQS-AGSQRGHGGGSGNF-MGH-GGN------FGGG---GGNFGRGG
NFGG--RDGYGGGG--------GGSRGS--YGGGDG------------------------
-GGYGGG-GP-G--Y--------G-NQGGGHGGG----G-GGNDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGPQQSNYGPMKGG-SFGGRSAG----SPYGGGYGTG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------LCGN-ER--PPNK----TFQGLRFY---A--------
-AMCARPHKVDGHVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDG-HDTVDKIVVQ--KYHT----INR
HNCE---------MQFA-GSQRGRGGGSGNF-MGC-GGN------FGDG---GGNFGLGG
NFGG--RGGYGGGG--------GGSRGS-YGGGD-GGY--NGFGG-DGGNYGS-------
-GGYGGGG-P-G--Y---------GNQGVGYGG-----GGGGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRRSG----SPYGGGYGSGG----GS---
---GGYGSR-----R-------------------------------------ESEELSGK
LQVTLRQLS------------QMH------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KCHT----ING
HNCEVKKALSKQEIQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGGGGSRGSYGGGDGGY--NGFG----------G---------------
------GYGGGP-GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGHMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------MEVKPPPPGSSRRCWREEGHDPNEPEQLRKLFIG-GLSF
ETTD--DSF----REHFEKWGTLTDCVVTR--DPQT---THSRGFGSVTCSC---VEEVD
AAMCAQPHKVDGRVVKPER-AVSREDS-VKPGARLTVKNIFVGGVKEDTE-EYNLRE---
--------------LLRKSGKK---RGFAF-AAFDD-HDTVDKIVVQ--KYHT----ING
HNCEVQKALSKQEMQSA-GSQGGRGGGSG---------N------FGGG---GGNFGRGG
NCDG--RGGYGGGG--------GGSRGS--YGGGDGRY--NGSGG-DGGNHGGGPGYS-S
RGGYGH-DGP-G--Y--------G-NQGGEYGSG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSLG----IPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------G---------------HDPKEPEQLRKLFIG-GLSF
ETPD--DSL----REHFEKWGTLTDHR-----PPKT---KLSRGFGFVTCSR---VEEVD
AA MCVQLHKVDRRVVEPKR-----VDS-VIPGAHLTVKKIFG GGIKEDTE-EYNLRDYFE
KY---GNIETIEVMEDRQSGKK---RGFKY-LTINE-H----------------------
-NC--------------------CGGRSGNF-MGC-GGN------FGRC---ENVG--G-
-------RGYYGGGGG--------NRGG--YG-GEGGH--NGFVG-DGGHYGSGPGYS-S
TGVYGGGGPG----Y---------GNQGGGYGGS----G-GRYDGYNEGGNFGGGN----
YGGDGHY---------NQSNYEPMKGS-IFGGRSSG----SPYGGGYGSDG---------
RS-GGF------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEAKLSPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETMD--DSL----REHFEKWGILTDCVVMK---PQT---KRSRGFGFVTYSC---VEKVD
VA MCARPHKVDGCVGEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTADKIVVQ--KYHT----ING
HNCDVKKALSKQEMQSA-GSQRGRGGGSGNF-MGH-GKN------FGGG---GGNFGYGG
NFGG--RGGYGGGD--------GGSRGS--YGGGGGGY--NGFGG-DGGNYGSGPGYS-S
RAMKGGSFGGRS--L--------GSPYSGGYGSG---GGSGGYSSRRF------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKLPPGHPQPNSSR-----------RRGEEGHDPKEPEQLSKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KHSRGFGFVTYSC---VEEVD
AAM CARPHKVDGHVVEPKR-AVSREDS-VKPGAHLTVKK IFVSGIKEDTE-ERNLRDYFE
KY---GEIETTEVKEDRQSGKK---RGFAF-------------------KYHT----ING
NNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGC-GGN------FGGG-----------
--------GYGGGG--------GGSRGS-Y-GGG--------------------------
---------------------------------------DK-DDGYNEGGNFGGG----N
YGDGGNYNDFGNYSGQ--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKRGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRV VEPKR-AISREDS-VKPGAHLTVKK IFVGGIKEDTE-EHNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NSGE--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG--G--PGY---------GNQGGGYGG----GG-GRYDGYNEGGNFGGNY----
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------MIEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPNR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG--DGGNYGGGPGYS-S
RGGYGGG-GP--GGY---------GNQGGG------------YGGYNEGGNFGGGNYGG-
---GGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------------G-----------------HTYR------------------
-----------------------LVCN-ER--SPNQ----TFQGLWFL--------DAA-
--MCARPHKVDGRAVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYLE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MG--------------------------
--------GYGGGG--------GGSRGS-YGGGD-GGY--NGFG--DGGNYGGGPGYS-S
RGGYGGGG-P-G--Y---------GNQGGGYGG----------------GNFGGG----N
Y GGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSGG----GS---
---GGYVAEGSKSSRKRA-------------------------TVLSR---RESEELSGK
LQVTLRQSN------------CKN------LPQKER------------------------
------------------------------------------------------------
-------------------------------------------

---------------------MEVKPPPPGSSRRCWREEGHDPNEPEQLRKLFIG-GLSF
ETTD--DSF----REHFEKWGTLTDCVVMR--DPQT---KHSRGFGSVTCSC---VEEVD
AAMCAQPHKVDGRVVKPER-AVSREDS-VKPGARLTVKNIFVGGVKEDTE-EYNLRE---
--------------LLRKSGKK---RGFAF-ATFDD-HDTVDKIVVQ--KYHT----ING
HNCEVQKALSKQEMQSA-GSQGGRGGGSG---------N------FGGG---GGNFGHGG
NCDG--RGGYGGGG--------GGSRGS--YGGGDGRY--NGSGG-DGGNYGGGPGYS-S
RGGYGH-DGP-G--C--------G-NQGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSLG----IPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------CSGSWT------SESGLKMEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQ--------RFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGD---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGSDGGY--NGFGG-DGGNYGGGPDYS-S
KGGYGC-GG---PGY---------GNQGGGYGGS----G-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDS-------------RPGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL---------------NCVVMR--DSQT---KRSRGFGFVTYSC---VKEVD
AA MCARPHKVDGPVVEPKR-AVSREDS-VKPGAHLTMKN VFVAGIKENTE-EYNLTYYFE
KY---GKIETIE------SGKK---RGFAF-VTFND-HDTADKIVVQ--KYHT----ING
RNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGH-GGN------FGSG---GGNLGRGG
NFGG--RGGCGGGG--------GGSRGS-YGG------------G-NGGNYGSGPVYS-S
RGAYGGSG-P-G--Y---------GNQG-----------GGGYDGYHEVGNVGGG----S
YGGGGNYNDFGNYSGQQQSNYGPMNRG-SFRKRSSG----SPYGGGYGSGG----GS---
---GGYGSRRFLKHQKRA-------------------------TTLRR---RESEELSGK
LQVTLRQ-----------------------LPKMH-------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRRR--------RSQGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGR-----------GDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFG--HDTVNKIVVQ--KYHT----ING
HNREVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS-Y-GGGD------------GGNYGGGPGYS-S
RGGYGGGG-P-G--Y---------GNQAHGSG-----GGGGGYDGYNEGGNFGGA----R
APPCGCRVRAA-------------------------------------SGG----GV---
---QGSGPGVREEQMVKR-------------------------REWEG---GP---IAAR
SRAGARTITMATEEGRTHPASCLFRTWN-LVPRLPTEGLGQNYKPQNPLHSSILPPVFLF
AKVFWEW-----------------------------------------------------
-------------------------------------------

---------------------------------MYLFSQGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGG----GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGKYFFI----------
FLVK-F-SIDFLI-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-----------GAVR----RWPGRN--------ATDGLEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKCGTLTDCVVMR--DPQT---KCSRDFGFVTYSC---VEEVD
GAICALPHK VDGRVVEPNR-AVSREDS-EK YTEEYNLRDY------------------FE
KY---GKIETIEVMEDRQSGKK---RNF-------------DKIVFQ--KYHT----INV
HNCEVEKALYEQEMQSA-GSQRGRGGGSGNF-MGR-GVN------FGGG---GGNFGRGG
NFGG--KGGYGGGG--------CGSRGN-YGRGG-SGY--NGFGG-DGGNSGGGPGYS-S
G-----GG-L-G--Y---------GNQGDGYGG------GGGYDGYNEGGNFGGG----N
YGGGGNYKDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSGG----GS---
---GRYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--DGGYNGF-G--------GDGGN--YGGGP-GY--SSRGG---------------
------YGGGGP-GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------M---RPQT---KRSRGFGFVTYSC---VKEVE
AARCARPHKADRCVVEPKR-AASTEDS-VKSGAHLTVKKTFVGRIKEETE-EYNLRDYFE
KY---GKIETADVREDRQSGKK---RGFAS-LTFDD-HDTVDKTVV Q--KYHHTGRAING
HNCEVKKVLSKQEMKGH---------------RGR-SGN------FGGG---GGNFGCGG
NFGG--REGYGGEG--------GGSRGS-YGGGD-GGY--NAFGG-DGGNYIGIPGYS-S
RGGYDGDG-P-R--I---------W-----------------WWWWSDGGNFDGG----N
Y GGGGNYNDFGNYSEQQQSNYEPMKGG-SFGGRSSG----IPYG------G----QS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------------MEPDSGHRH------RR--RWQEGHDPKEPERLRELFIG-GLNF
ETTD--DSL----REHFEKWGILTDCVVMR--DPQT---KHSRGFGFVIYSC---VEEVD
AAMC-----VDG HVVEPKS-CFQREDY-LKSDAHLTVKK IFVGGITEDTE-EYNLRDYFE
KY---GKIETIEIMEDRQSGKK---RGFAF-VIFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKVLSKQEMQSA-GSQRGRGGGSGNF-MGH-GVN------FGGG---GGNFGGGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGS-DSGNYGGGAGYS-S
RGGYGGGGP--G--Y--------G-NQGGEYGSG----G-GGYDGYNEGGNFGSR----N
HGGGGNYNDFENYSGQQQSNYGPMKGG-SFGGRSSG----SPCGSGYGSG----------
GGRGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------KTAAGCPQPGSGHCRR--------CQGEEGHDPKEREQLRKPFIG-GLSF
ETID--DGL----REHFEKWGTLTDCVVMR--DPQT---KCSRGFGFVTYSY---IEEVD
AAM CARPHKVDGCVVEPKR-AVSREDF-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVIEDRQSGKK---RGFAF-VTFDD-HDTVDKILVQ--KYHT----ING
HNCEVKKPLSKQEMQSA-GSQRGCGD----------------------------------
-------------------------------------------GSGDGGNYGGGPGYS-S
RGGYGR-GGP-G--C--------G-NQGGGYGGG----G-GGYDGYNEGGNFGHG----N
YGGGGNYNDFGNYSGQQQSN----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------------MTYSI--------ACWGEEGHDPKELVKLKKLFIG-DLS-
------DSS----REHFEKWGILTDCALMR--DSQT---KCSRGFGFVAYSY---VGEVD
AAI CAGPHKVDGCVVEPKI-AVSREDS-MKPGAHLTVKK IFVGDIKEETG-EYNLRGYFE
KN---GKIETIEVMEDRQSGKK---SKFAF-ITFDD-HDTADKI-VQ--KYHT----ING
HNCEVKKALSKQDIQSA-RSQRGHGGRSGNF-MGH-GGN------FGGG---GGNFGHGG
NLSG--RGGYGGGG--------GSSRG-----GN-GGY--NEFED-DGGNYGSGPGYS-S
RGGYGAGG-P-G--Y---------GSQSGGYDS------GGGYDGCNEGGNFGGG----N
YGGGGSYNDFGNYSGQQQSNYRSMKVD-SFGGRSSG----SPCGGGYGSGG----GS---
---GGYGSRRFLKNNRIG-------------------------LQFLA---GERAKSCQE
SCRLL-------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGG----PGY---------GNQGGGYGG-----G-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------M---RPQT---KRSRGFGFVTYSC---VEEVE
AARCARPHKADRCVVEPKR-AASTEDS-VKSGAHLTVKKTFVGSIKEETE-EYNLRDYFE
KY---GKIETADVREDRQSGKK---RGFAS-LTFDD-HDTVDKTVK----YH---HSING
HNCEVKKVLSKQEMKGH---------------RGR-SGN------FGGG---GGNFGCGG
NFGG--REGYGGEG--------GGSRGS-YGGGD-GGY--NAFGG-DGGNYIGIPGYS-S
RGGYDGDG-P-R--I---------W-----------------WWWWSDGGNFDGG----N
Y GGGGNYNDFGNYSEQQQSNYEPMKGG-SFGGRSSG----IPYG------G----ES---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKLPPGRPQPHSSCRH--------RCWGKEGLDPKETQQLRKLFIG-GLSF
ETTD--DSL----REHLEKWGTLRLCGNER--SPNE----TFQGLWFCDLSC---VEEVD
VAMCAPPHKVDGRVVEPKR-AVSRVDS-VKPGAHLTVKKFFVGSIKEDTE-EYNLRDNFE
KH---GKIETIEVTEDRQSGKK---RGFAF-ITFDD-HDTVDNFVVQ--KYHT----ING
HDCEMKKAPSKQEMRSA-GSQGGRGGGSGNF-MGR-GGN------FGGG---GGNFGH--
--------GYAGGG--------GSSRGS-Y-GGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGY----------------------GG-----GGGGGYDGYNKGGNFGGG----N
YGG--------------QSNYGPMKGG-SFGGRSSG----SPYGDGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTH-------------------
-----------------------------------------RLGFGFV--------TYPC
VEEVDAAMCVDGRVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNYEVKK--------SA-GSQRSRGGGSGNF-MGR-GGN----------------FGRGG
NFGG--RGGYGGGG--------GGSRGS-YG-GD-GGY--NGFGG-DGGNYGRGPGCS--
RGGY-GGG-P-G--Y---------GNQGGGYGS-----GGGGYDGYNEGGNFGSG----N
YGGGGNCNDFGNYSGQ------------HFGGRSSG----SPYGAGYGSGG----GS---
---GGYGS-------RRA-------------------------IVLSR---RESKELSGK
LQVTLRQLN------------CKN------LPQKEL------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------SE--------GHGHDPKEPKQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTFTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDA-VKPGAHLTVKKI FVAGIKEDT--EYNLRDYFE
KY---GKIETTEVTEDRQSGKK---REFAF-VTFYD-HDTVDKI-VQ--KYHT----ING
HNCEVKKAFSKQEMQSA-GSQRGHGGGSGNF-MGR-GGN------FGGG---GGNFGPGG
NSGG--RRGYGGGG--------GGSRGS--YGGGDGGY--NGFG-GDGGNYGG-------
--YG-G-GGP-G--N--------G-NQGGGYGGG----G-GGYDGYNEGGNFGSH----N
HGGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSGG---------
-GSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MRVKQEPSHPQLDSSHPS--------LRWGEEGHYPKKPD------------F
EITE--DSL----REYFEKWGTLTDGVVMR--HPQT---KCSRGFAFVTYSG---VEEVD
AA VCARPHKWNQKGLI----------------LERTHEENFA GGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQRGKK---RGFAF-VTFDG-HDTVDKIVVQ--KSHT----SNG
HNCDVKRAFSKQEMQSS-GSQRGRGGRSTNF-MGC-RGN------FGGG---RENFGCGG
NFGG--RGGYGGGG--------GGSRGS-YGGGD-GGY--NGLGG-DGGNYGGGPGYS-S
RGGYDGGG-P-G--Y---------ENQDGGYGG-----GGGGYDGYNEGGNFGGG----N
YGGGGNCNDFGNYSGQQQSNYGPMKWG-SFCGN-SG----SLYGGCYGSGG----GS---
---GF-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------IRPQPDSGR-H-------CRRVGEEGHDRKEPEQLRKLFIG-GLSF
ETTDDNDSL----REHFEKWGTLTDCVVMR--DPQT---KCSRGFGFVTYSC---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAHPTVKK IFVSGIKEDME-AYNLRHYFE
KY---GNIETTEVMEDRQSGKK---RGFTF-VTL------------I--KYHT----ITG
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GRSTGS--YGGGDGGY--NGFG--DGGNYGGGPGYG-S
RGGYGG-GGP-G--Y--------G-NQGGGYGGD----G-GGYDGYNEGENFGGG-----
----TNYNDFGNYSGQ--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPVRTQPDSSRRRRRHG--------EEGHDPKEPKQLRKLFIG-GLSF
ETTD--D-----------------NCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AA MCARPHKVDGPVVEPKR-AVSREDV-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVMEDRQSGKK---REFAF-VTFYD-HDTVEKIV-Q--KYH----TING
HNCEVKKAFSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGPGG
NSGG--RR-------------------G--SK-RKLVF--LHFTA-SRECPHFLT-----
RGHLPTSKPE----M---------ASQVSHC--I----TLTHTQLPPSPTIKRPLV----
ITLGPAR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFTG-GLSF
EATD--DSL----REHFEKWGTLTDCV-------------RSRGFGFVTYSC---VEEVE
AAMC ARPHKVDGRPVEPKT-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMED----------RFAF-VTFDD-HDSVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGGGCG--------
---------CGG-----------------GGGGSDGGY--NGFGG-DGGNYGGGPGYR-S
RGGYGGGG-P-G--Y---------GNQGGGYG----------------GGNFGGG----N
YGGGGSYSDFGNYSGQQH-----------FGGG----SSSSPCGGGYGHGG----GS---
---GGYGSKGFRNSREGL-------------------------QFLAG---ER----ARS
CQE----------------STGYFET----VAPKALEEL---------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGRR--------RRRRGEEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSLR----EHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGG-GGSRGSYGGGDGGN--YGGGP-GY--SSRGG---------------
------YGG-GP-GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------MG--------EEGHDPKEPEQLRKLFIG-DLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFDFVTYSC---VEEVD
AAM CARPHKVDGSVVEPKR-AVSREDS-VKPCAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGHSG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFG-GDGGNYGGGPGYS-S
RGGYGG-GGP-G--Y--------G-NQGGGYGG-----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQSFICCSFVFFFFFSLYQVY----CPVNC----GS---------
-GTRNKKLRNF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------LCGN-ER--PPNK----MLQGLWF-------------
-SMCARPHKVDGCVVEPKR-AVSREDF-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETTEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGCGDGSENF-GGG-GGN------F-GC---G------G
NFGG--GGGYAGGG--------SGSRDS-YGGGD-GGY--NGFGG-DGGNYGGGPGYS-S
RGGYGRGG-P-G--C---------GNQGGGYGG-----SGGGYDGYNEGGNFGRG----N
YGG------------------GLMKGG-SFGGRSSG----SPYDGGYGSGG----GS---
---GRYGSR-----RA---------------------------TVLSR---RESKELSGK
LQVTLRQWN------------CKN------LPQKEQ------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVRLLSGHPQPHSSLRLCPGG--------RGGHDLKEPEQLRKLFIG-GF--
ETTD--DSL----REHFEKWGTLTDGVVMR--VPQT---ERSRGFG SMTSSC---VGEVD
AAVYSRPLR----VVEPKR-AVSREDS-VKP-------K IFVGGIKEDTE-ECNLRDCFE
KY---GKIKTID------SGKK---RGFAF-VTFDD-HDLVDNIVVQ--KYH----TING
HNCEVKRPLPKQELQS----QRGLGDESGNF-MGL-GGN------FGGG---GGKFGSGG
NFGG--RGGYGGGGGG--------CRGS--YGGGDGTY--NGFGG-DGGNYGGGPGYS-S
RAW----CA---------------------------------GGGPEHDRNFGCGNYS--
--GGENYNDFGNYSGQQQIT-DPCRGC-SLSGRNSG----SPCGGGYGSGG---------
GS-GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGHPQPNSGRRRCRWG--------EEGHDPKEPEQLRKPFIG-GL--
------------------------NCVIMR--DPET---KRSRGFGFVTYSY---VEEVD
AAMC ARPHKVDGRVVEPKR-AVSREDS-VKPGAYLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETLEVTEDKQSGKK---RGFAF-VTFND-HDT---------KYH----TING
HNCEAKKALSKQEMLSA-GSQRGRGGGSGNF-MG---GN------FGGG---GGNFGHSR
SGGN--YGLWLG-EAA--------KTEG--SK-GKAGI--QGLEG--PEADEIEM-----
DG------EE----G---------ASGISV------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------GHEPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMSARPHKVDGRV VEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLREYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQTA-SSQRGRGGGSGNF-MGR--GN------FGGG---GGNFGRGG
NFGG--RGGYGGGG-G-----GGGSRGS--FGGGDG-Y--NGFGD--GGNYGGGPGYG-S
RGGYGGGGGP-G--Y--------G-NPGGGYGGG----G-GGYDGYNEGGNFGGG----N
YGGSGNYNDFGNYSGQQQSNYGPMKGGGSFGGRSSG----SPYGGGYGSG----------
SGSGGYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MKVKPPPGRPQPDSGRRR------RRRCRGEEGHDPKESEQLRKPFTG-GLTH
S----------------EKWGTLTDCVVMR--DPQT---NRSRVFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-PVSGEGS-VKPGAHLTVKT IFVGGIEEDTE-ECNLRDYVE
KY---GKIETTEVLEDGQSGQK---RGFAF-VTFDD-HDTVDKIVVQ--QYHT----VNG
QNGEVQKALSKQEMHSA-GSQRGRGGGSGNF-MGR-AGS------FGGG---GGNFGRVG
NFGG--RGCYGGGG--------GGSRGS--YGGGDGGY--NGSGG-DGGNYGGGPGYR-S
RGGYGGGGP--G--Y--------G-NRGGGHGGG----G-GGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGGGYGSG----------
GGSGGYGSSRL-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------MEGHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----SEHFEKWGPLTDCVVMR--DPQT---KRSRGFGFV-----------D
AALCAQSHKFDGRVVEPKR-AVSREGS-VKPGTHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIE-------------RGFAF-VTFDD-HDKVDKIVVQ--KYHT----ING
HNCGSG------NFTG------------------C-EGN------FGGG---GGDFGHGG
NFGG--RGGYSGGG--------GGIRGS-YGGGD-GGY--NGFGG-DGGNYGGRPGYS-S
SGGYGGGG-P-G--Y---------GNQGGGYGG-----GGGGYNGYNEGGNFGGG----N
YDGGGKYNDFGNYSGQQQSNYGPMKGG-SFGGRSSG----SPYGVGYGFGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPGRPQPDSGHRR--------RRRWEEGHDSKEPEQLRELFIG-GLNF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRFRGFGFVIY----------
----SCVEEVDAAMCCKSV-PISSEDY-LKSDAHLTVKKIFVGGITEDTE-EYNLRDYLE
K----------------QSGKK---RGFAF-VIFDD-HDTVDKIVVQ--KHHT----ING
HNCEVKKVLSKQEMQSA-GSQRGRGGGSGNF-KGH-RVN------SRGG---GGNFGRGG
NFGG--RGGYGGRG--------GDSRGS-YGGGD-GGY--NGFGS-DSGNYGGGPGYS-S
RGGYGGGG-P-G--Y---------GNQGGEHGS-----GGGGYDGYNERGNFGGR----N
YGGGGNYNDFGNCSGQQQSNYGPMKGG-SFGGRSSG----SPCGGGYGSGG----GR---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------MR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMCARPHKVDGRVVKPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----INW
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGG--G--PGY---------GNQGGGYGG----GG-GGYDGYNEGGNFGSNYG---
--DGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPLPGHPQPNSSRHV---------GQGEEGHDPNEPEQLRKLFIG-GLSR
ETTD--DSL----REHFEKWGTWTDCVVMG--DPQT---KCSRGFDFVTYSC---VEEVD
AVMY AQPHKVDGHLVEPKR-AVSTEDS-VKSGA-LTVKK IFVGGIKEDIE-EYNLRDYFE
KY---GKIETTEVMEDRQSGKK---RRFAF-VTFND-HDTADKIV---------------
-------VQKYH------------------------------------------------
-------TN--------------NGRGS-Y-GGGDGRY--NGLGG-EDGNYRGGPGYS-S
RGG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

----------------------MDD------HWPSTDDQGHEPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEQWGKLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAMSARPHKVDGRVVE PKR-AVSREDS-ARPGAHLTVKK IFVGGIKEDTE-EYHLRDYFQ
SY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQTA-SAQRGRGGGGSNF-MGR-GGN------YGGGGGGGGNFGRGG
GFGN--RGGYGGGG--------GGGRGGGYGSGGDGGY--NGFGG-EGGNYGGGPGYGGR
--G-YGGS-P-G--Y---------GNQGGGYGGGGSGGGGGGYDGYNEGGNFGG------
----GNYNDFGNYGGQQQSNYGPMKGG-SFSGRSSGGSGSGPYGGGYGSGG----GGGGG
GGGGSYGGRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

-------MEVKPPPP----GSSRRR--------RCQREEGHDPNEPEQLRKLFIG-GLSF
ETTD--DSS----REHSEIWGTLTDCVVMR--DSQT---KRSRRFGFVTCSC---VEEVD
AAMCARPHKVDGRVVKPKR-AVSREDS-VKPGAPLTVKHI--------------------
FY---SKIETTEVMEDRQSGKK---RGFAF-ATFDD-HDTVDKIVVQ--KYHI----ING
HNCEVQKALSKQEMQSA-GSQRGRGGGSGNF-IVE-ETLEVVEVILAVV---ETLVE---
-E-----EAYGGGG--------GGSRGS-YGGGD-GRY--NGFRG-DGGSYGGGPGYS-S
RGDYGHDG-L-G--C---------GNQGGGYGG-----SGGGYDGYNEGGNFGGS----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSLG----IPYGGGYGSGG----GS---
---GGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------------------------------GHDPKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFEKWGTLTDCVVMR--DPQT---KRSRGFGFVTYSC---VEEVD
AAM CARPHKVDGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCEVKKALSKQEMQSA-GSQRGRGGGSGNF-MGR-GGN------FGGG---GGNFGRGG
NFGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGGGPGYS-S
RGGYGGGGP----GY---------GNQGGGYGG----GG-GGYDGYNEGGNFGGGNY---
-GGGGNYNDFGNYSGQQQSNYGPMKG-GSFGGRSSG----SPYGGGYGSG----------
GGSGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

--------------------------------------EGHSAKEPEHLRKLFIG-GLSF
ETID--DSL----REHFEIGA--------------H---SQIVGFGFVTYSC---VQEVD
GAMCAQPHKVDRYVVEPKR-AISREDS-VKLGAHLTVKKIFVGGIKEDTK-EYNLRDYFE
KY---GKIETIEITEDRQSVKK---RGFAF-VTFDD-HDTVDKIVVQ--KYHT----ING
HNCER-KALSKQEMQSA-GSQRGQGGGSGNF-MGR-GGN------FGGS---GGNFGRGG
NFGG--RGGYGGRG--------DGSRGS-Y-GGGDGAY--NGFGG-DGGNYGGGPGYS-S
RRGYGGGH---------------------------------------GGGNF-RG----N
YGGSRNYNNFRNCSGQQQSNDGPIKGG-SFFFFFFETESHCVA-----------------
-------QARV---SAVA-------------------------SSWLT---AT-------
-----------------------SNSWA--------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------------------------EEDHDSKEPEQLRKLFIG-GLSF
ETTD--DSL----REHFE-WGTLTDCVVMR--DPQR---KHSRGFGFVTY SC---VE---
------PHKADGRVVEPKR-AVSREDS-VKPGAHLTVKK IFVGSIKEDTE-EYHLRDYFE
KY---GKIKTIEVVEDRQSGKK---RGFAF-ATFDD-HDTVDKIVVQ--KSHT----ING
HNCEVKKALSKQEMQSA-GLQRGHEGGSGNF-MGW-GGN------FGGG---GGNFDRGG
NLGG--RGGYGGGG--------GGSRGS--YGGGDGGY--NGFGG-DGGNYGSGPGYS-S
RGGYGGGGP--G--Y--------G-NQGGGYGG-----G-GGYEGYNEGGSFG-G----N
YGGSGNYNDFGNYSGQQQSNYGPMKGG-SFGGRSLG----SPYGGGYGSG----------
GGIGGYGSRRF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

---------------ME--VKLLPGG-PK--------PNSGCGYHRRGKGKLFIG-GLSF
ETTD--DSL----REHLEKWGPLTDCVVMR--YPQT---KSSRGFGFMTHSC---VEEVD
A ATCTQPHRLKT---------VSREDS-IKPDAHLRVKKN FVGGIKEDTE-EYNLRDYFE
KY---GKIEAIEVMEDRQSGIK---RGFAF-ATFDD-HDTVDNIVVQ--ECH----TING
HNCE---------MQSA-GSQRGCGGGSSNF-VGY-RGN------FGGG---GGNFGRGG
NFGG--RGGYGGGGGG--------SRGS--YGGGDVGY--NGYGG-DSDNSGSGPGYS-S
RGGYGGDGPG----Y---------GPR---------------------WK-FGGGN----
YGGGGNYNDFGNHRG--------SFCG-RSSDMAQG----G----GYGGG----------
-G-GGYDGYNE-------------GGNLAV-VTMVVVGTIMILEIIVDNSNQIMHPRKGV
VFVEEAQSSLCWWL----------WIW---------------------------------
------------------------------------------------------------
-------------------------------------------

-------------------MG-----------------HTHR------------------
-----------------------LCGN-ER--PPNK----TFQGLRFY---A--------
-AMCARPHKVDGHVVEPKR-AVSREDS-VKPGAHLTVKKIFVGGIKEDTE-EYNLRDYFE
KY---GKIETIEVMEDRQSGKK---RGFAF-VTFDG-HDTVDKIVVQ--KYHT----INR
HNCE---------MQFA-GSQRGRGGGSGNF-MGC-GGN------FGDG---GGNFGLGG
NFGG--RGGYGGGG--------GGSRGS-YGGGD-GGY--NGFGG-DGGNYGS-------
-GGYGGGG-P-G--Y---------GNQGGGYGG-----GGGGYDGYNEGGNFGGG----N
YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGGRRSG----SPYGGGYGSGG----GS---
---GGYGSR-----R-------------------------------------ESEELSGK
LQVTLRQLS------------QMH------------------------------------
------------------------------------------------------------
-------------------------------------------

Query Results

"ENSGT00900000140828_1"

ENSGT00900000140828_1