ENSGT00900000140820_0 : Linker Region Query Results

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-------------------------------------------------M-----SVRFS
SASRRLG--------SVRLSSP---G-AALGAGNTCGV-PGIGSGF-SCAFGGSSLAGGL
G------------------MGGASCGAFTVNEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRTQIISATAQNANI
VLQNDNARLTA-DDFRMKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLSEE
LAYLKK--NHEE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGSCVKS----K--GQGGPGNQTK-DSPKTAIV
KTVVEELDPRGKVLSSRVHTLEEKSTKVNNKN----EQRIPS--------

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----------FGGGSG---LVEALCFGGGSG--FGGGS----------------GFSGGS
G--------FGGGSGFGG---GSSFGGGASGG----FYSYGGG-------MGGGMG-G--
GVGDGGLFSGGEKQTMQNLNDRLASYLDKVRALEEANTDLE---IKIKEWYEKFGPRSGD
NGSG-RDYSKYYPIIEDLRNQIITATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGDVNVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKSEITELKRTLQ---SLEIELQS
QLAMK---SSLEGXXXXXXXXXXXXXXXXXXXISSL-EEQICQIRGETECQ--NAEYEQL
LNIKTRLEMEIE----TYRCLLDGEGGGGSDFEGVFYFRSSGSRNT--------G-----
------------S-KG-------------------------------------------S
M-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
S----SGQGRDP---SK----S-----------------RVTK-----------------
---------------TIVEEVVDGKVVSSQVSNI----SEVKF---------K-------
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-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFMAGNVCVG-SGAGSSF-SCTLGGISS----
----GGSFC-NSGGG----LGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHA
LEEANADLEQKIKGWYEKCEP-GSSREHDHD---YS-RYFSVIEDLKRQIISATICNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTNGLRRVLDELTLCTTDLEIQCETLSEE
LTYLKK--SHEE----------------------EMEVLQYTAGGNVNVEMNATPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--WFNERSATLQQQISDHEGAATAARNELTEIKRNLQ
TLEIELQSLMAV----KHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQK
LEYEQLLDVKIFLEKEIEIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAK-DSTEETIV
KTVVEELDQIGNLLSLRVHSVEEKSSKISNITV--EQRVPSKAP------

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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSNF-SCAFGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

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--------------------VD----------------------LSSNTMS---------
-----------------------------LSVRTSGLPRRLSS---Q-S----GTSGR--
---------------ARGTTAS--IV-GSS-----YGGS----TFGFGD---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------ISFA---GGLGTAYGGALGGGSGAL-----------------G-----
-------------G-------GFGGLGGGFGGLGIGF---GGGPG----G--GSV--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANAELE---NKIREWYETRGSGTGD
PGSQ-SDYSKYYPLIEDLRNEIISASIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALHQSVEADINGLRRVLDELTLARADLEMQIENLTEELAYLKKNHEE----
-ELQSFRAGG-PGEISVEMDAAPAVDLTRLLNNMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLATK---KSLEVSLAEVEGDYCGQLSQVQQLIGSL-EEQLLQVRTDTEHQ--NADHQRL
LNAKARLELEIE----TYRRLLDGEAQGDSFDETL---YVTESKPQ--------------
----------------------------------------TQSI-D--------------
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-------SSKEQSK-------S-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVQEDLM------------------------
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---------------------------MSHS-------TRVSS---S-------RAGGSS
---------------SARVSAGGSSF-SGGSRCGLGGSL----AWGFRGGT-G-----G-
----------------------CGLSGGSSSAFGGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSSGASGG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSR-RDYSKYYSIIEELRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQVSAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
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----------------------------MATSFVSSS-STYGG----------GFGGA--
GG--------------------SSS-RLSSMR-------AGS---SYRAPSIHG------
---------------G-SG--------------GRGVSVSSARYVSSAG-GGCG------
-------------------------FGGGYGGA------------------FGGGAACGF
GGGSGFGGGSGFGGG----------------A-----------------CFSGGFDLGSG
YGGGDGLLSGNEKITMQNLNDRLASYLDKVRALEEANSDLE---VKIRDWYQKQAPTS--
---PARDYSNYYKIIEDLRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELFLRQSVESDINGLRRVLDELTLSRADLEMQIETLKEELAYMKKNHEE----
-EMKEYSNQL-SGTVNVEMDAAPGIDLTRVLAEMREQYEALAEK-NRKDAE---AWFFTQ
----------------TDELN-REVATHTQQ--IQTSKSEITELRRTLQ---GLEIELQS
QLSMK---AGLEANLRDTEGRYCAQLAQIQALITSV-EEQLGELRCDMERQ--NQEYKML
MDIKSRLEQEIA----TYRQLLEGQDSQL-TGLNPKDAFG--RGRSGAED----------
-------DGKSSSTRDRRFQ----------------------------------------
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--------------------------MASYSFRQTSS-----S----------V-GGP--
-G-------------------------ASSLR-------YS-GS--FRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSGLGSGLG------
------------GC------YGGGSFSSS------------------------------F
S------YG----GGL-G------------------------------------------
---GDGLLSGNEKATMQSLNDRLASYLEKVRALEEANSDLE---TKIRNWYQKQGP-S--
---PARDYSPYFKTIEDLRDKILDATIDNA------------RIVLQVDNARL-AADDFK
T-KF-ETEQGLRMSVEADINGLRRVLDELTLSRADLELQIEGLKEELAYLKKNHEE----
-ELSALRGQV-AGQVSVELDSAPGIDLAKILADMREQYENMAEK-NRKDAE---AWFHSK
----------------TEELN-REVTVNTEQ--LQSSKSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLADTEARYGAQLAQIQGLVGSI-EAQLAELRADMERQ--NTEYKIL
MDIKTRLEQEIA----TYRQLLEGQESQM-FGSLSGTADKRD------------------
---------KH-------------------------------------------------
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---------------------------MSCL-------SRIS----S-------RAGGSS
---------------CARVSGGGSSF-SSSSRCGMGGGS----ARGYGGS--S-----S-
----------------------CGLGGGSGSGFGGG-------------------FGGGF
SCGSAV--GGYGGGSG-----SGAGFGGGASGGF--------------------------
----------------------YSYGGGAGGG----SG--YGG-------FG--------
-SGDGGLLSGSEKQTMQNLNDRLASYLDKVHALEEANTDLE---VKIKEWYDKFGPGSRD
GGAG-KDYSHFFPVIEDLKNQILHATVENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLRQCVEADTNGLRKVLDDLTMARSDLEMQIESLTEELAYLKKNHEE----
-EMKNMQSSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEDLAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---GLEIELQS
QMAMK---SSLEGTLADTEADYVAQLSQLQQQISNL-EQQICEIRGEMECQ--NAEYEQL
LNIKTRLEMEIE----TYRRLLDGEGSGSS-------SGGSGSW----------------
---------------KS----G--------------------S-----------------
G-----------------------------------------------------------
---------------------------------------------------SGDSRS-GT
S----SGQGKDSNK-------T-----------------RVTK-----------------
---------------TIVEEVVNGKVVSSQVSNV----SEVKVK----------------
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--------------------MECSTQRWSCS-------SRVSS------------SGA-S
---------------GRGAHAGGSIY-SNGSSCGLGASP----SWAFQGSS-N-----S-
----------------------CGLSGGPKGGFG-----------------------RGF
GSCVVT--GGFGAASG-----------------FGAGS----------------GFGGGS
G--------FGGGSGFGG---GSGFGGGSGFG---GSSGFGGG-S-----GFGSLG-G-G
SGGDGGLLSGTEKQTMQNLNDRLASYLDKVRALEEANADLE---TKIKAWYSKHGSG--K
DDCG-RDYSKYWPVIEELKNQVISAIIENA------------RRTLQMDNARL-AADDFR
M-KY-EHELCLRECVEADINGLRKVLDDLTMTRSDLEMRIESLTEELVLLRKNHEE----
-EMKCTQGRS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEALAEH-NRQEAE---RQFNER
----------------SASLQ-VQISTDAGA--ANSAKNEVMELRRSVQ---TLEIELQS
LLAQV---CSLEGSLADTEAGYRSQLSGIQTQISCL-EEQLSQIRGETQCQ--KAEYECL
LNIKTRLEEEIE----TYRRLLNGEGGGC-------DYGNLASRH---------------
-----------------------------------------------------------V
V-----------------------------------------------------------
---------------------------------------------------LSDSRS-GS
C----SGQGKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQVSSI----SEVKIK----------------
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-------------------------AMTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------GLG-GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GX----------------
----------------GG-GSYSSCYSFGSGS----------------------------
--------------GYGG-----GFG----------------------------------
--AVEGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSHYYQTIEDLKNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADTNGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
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--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLG------
------------S-ALGG-NSYSSCYSFGTGS----------------------------
--------------GYGG-----NFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSAYYQTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
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-----------------------MAATTTSIRQFSTS-GSVKG--------LCGPG----
----G-----------------GFS-PMSSVR--------------VGGA-CRAP-----
---------------SLLGV----------GSCGTMSV-TSSRFS-----AGLG------
--------GGYG-------G----GYTCSLGGGFGS------------------------
--------------GFG-------------------------------------------
--SSDALLGGSEKETMQNLNDRLASYLDKVRALEEANADLE---VKIHDWYKKQGPGP--
---A-RDYSHFFKTIEELRNKILAATIDNA------------SLVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADTNGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLEGSLAETEARYGAQLAQLQGLISSI-EQQLGELRCDMERQ--NQEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------ISQ
P-----TREATVTTRQVRTI----ME------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
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---------------------------MSCS-------SRVSS---S-------RAGGSG
---------------LARVSVGGSSF-TSGSRCGVGSGS----TRGFRGGT-G-----S-
----------------------CGLSGVSSSGFGGS-------------------FGGGF
GSCSVG--GGLGGTSG-----SGAGFGGGSG--FGGGS----------------GFGGGS
G--------FGGGSGFGG---GSGFGGGASGG----FYSYGGG-------MGGGMG-G--
GIGDGGLFSGGEKQTMQNLNDRLASYLDKVRALEEANTDLE---NKIREWYDKFGPGSGD
GGSG-KDYSKYYPIIEDLRNQIITATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLRQAVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRARYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QMAMK---SSLEATLADTEAGYMAQLSEIQMQISSL-EEQICQIRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGCGS-GFGGS-DFRNSGSRNT--------G-----
------------S-RNM----G--------------------SR-DM------------S
M-----------------------------------------------------------
---------------------------------------------------SGESRS-GS
C----SVQGRDP---NK----T-----------------RVTK-----------------
---------------TIVEEVVDGKVVSSQVSNV----SEVKV---------K-------
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--------------------------MTSYSYRQ----SSSTS----------TMGLG--
-S-------------------------NNSAR-------FGSGT-TFRAPSIHG------
---------------G-SG--------------GLGVSVS--RFVSSGVSGS--------
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-----------YGGSG---------SS----F-----------------S--------LG
YGGTDGLLAGNEKITMQNLNDRLASYLDKVRALEEANCDLE---VKIRDWYQKQGP-G--
---PARDYSAYMKTIEDLRDKILGATIDNS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRKVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMSALSGQI-GGQVSVEVDSAPGIDLAKILNDMRSQYEAMVEK-NRNDAE---AWFTTK
----------------TEELN-REVAVHSEQ--LQTSKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYGAQLSQIQVYISNI-EAQLSDIRADTERQ--NQEYLLL
MDIKTRLEREIA----TYRSLLEGHDSQD-TSVCISQK---SV-----------------
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-------------------------------------------------M-----SLRFS
SGSRRACPRPTTASGSLRLSGG---G-ASFGAGNACSM-PGIGSSF-SCAFGGST-SGGN
G------------------VGGNPCAGFTLNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDTEA--WFNEKSASLQQQISEDAGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLSETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGEEGACKSGGYKSKDYGSGNMGAQLK-DPIKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

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-------------------------------------------------M-----SVRFS
PASRRLGSCGG--AGSGRLSSG---G-AGFGVGSACGV-PGFGSSF-SCAFGGSSSAGGY
GAG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIISATASNASI
VLQNDNARLTA-DDFRLKFENEQALHQGVDADISGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIEFQSLLAM----KHSLECSLSETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGEDGSCVKS----K--GYGGPGNQIK-DSSKTIMV
KTIVEEIDPRGKALASRVHAMEEKSTKASTMKS--EPRVPS---------

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-------------------------------------------------M-----SLRFS
SGSRHICLRSG--AGSLRPSSG---G-TGFASSNICSS-SSAGSGF-SNALGGGLG----
----SASVGSHAGGT----LGSAACAGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLERKIKGWYEQHGP-SSCRGLDHD---TS-RYHPTIEDLKNKIISSTTANANI
ILQIDNARLAA-DDFRLKYENELALHQNTEADINGLRQVLDELTLCRTDQELQYESLSEE
MTYLKN--HDE-----------------------EMRALQCAAGGNVNVELNAAPGVDLT
VLLKNMRAEYEALAEQNRRDAEA--GFHEKSATLQQQISDDAGAATSARSELTEMKRSLQ
TLDIELQSLLAT----KHSLECSLSETEGSYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGDGNSCS----KSKGFGSGNSGNSSK-DLSKTTLI
KTVVEEIDQRGRVLSSRVQSIEEKTSKVTNGKT--EQRLPF---------

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--------------------------MTTCSRQYTSS-SSIK---------------SS-
GGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-SSSRYSSGGV-CGLG------
--------GGYGGGF----SSS-SSFGGALGSSFGG--------------GYGGGLGAGF
GG----G----FGGGVGG-----GFGGG------------------------------F-
GV-GDGLLAGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRLSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTLQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVSS-SRQVRT-K---VV------------DVHDG--KVV------S-----
---------THEQ---------------I--VRTKN------------------------
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--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTSGLPRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGA---S-----S-
-GGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGGGFGGLGMGF---VGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGAGD
A-SQ-NDYNKYYPLIEDLRNKIISASIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTVTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NMDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLDES---LFVTDSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTTS---------
-----------------------------LSVRTSGLPRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGA---G-----S-
GGGFSA-A---SM--FGSS---SGFGVGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGGGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGAGD
A-SP-NDYSKYYPLIEDLRNKIISASIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTMTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEIDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
SASRRLG--------SVRLSSA---G-AALGAGNACGV-PGIGSGF-SCAFGGSSLAGGL
G------------------MGGASCGAFTANEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRTQIISATAHNANI
ILQNDNARLTA-DDFRMKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLSEE
LAYLKK--NHEE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCRLIDGDEGSCVKA----K--GQGRPGNQTK-DSPKTAIV
KTVVEELDPRGKVLSSRVHTLEEKSTKVNK-T----EQRIPS--------

------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
GGSRHVGIQS----GSLRPPSG---G-AGFAGSSVAGG-SVAGSGF-SWALGGTLG----
----SAPGGSHATGA----LGNVSGVCFIGSEGGLLSGNEKVTMQNLNNRLASYLDNVKA
LEEANSELEKKIKTWHEKYGP-GSCRGLDRD---YS-KYHLTIEDLKSKIISSTAANANI
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQISNDLGAATSARTELTELKRSLQ
TLEIELQSLSAT----KHSLECSLAETEGNYCSQLAQIQAQISALEEQLHQVRTETEGQK
LEHEQLLDIKAHLEKEIETYCRLIDGDENSCS----VSKGFESGSSGNSPK-DVSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKMSKMSNGKA--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSHA---------------------R------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKVGGGLTVGK-------------SSEMLGKLCL-AATISF
E-RF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GIEIELQS
QLSMK---AALEDTLEETEARFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MSTTVRQFSSS-TSLKG--------FGSLG----
----G-----------------GSS-RLSSVR--------------LGAGGYRAP-----
---------------SVH------------GGSGSYSV-SS-RVV-----SGLG------
--------SAFG-------GSYCSSAGGALGGGFGG--------------SYGAGFGA--
-----------------------GFGGG------------------------------FG
GGD--GILPAGEKETMQNLNDRLATYLDKVRALEEANTELE---VKIREWYKKQAPGP--
---D-RDYSPYYRTIEELRNKVLVATVDNS------------NLLLQIDNARL-TADDFR
T-KF-ESEQALRLSVEADINGLRRVLDELTLSRADLEMQIENLKEELTYLKKNHEE----
-EMTALRGQV-GGEISVEMDAAPGIDLTKILAEMREQYESLAEK-NRRDAE---QWFFSK
----------------TEELN-REVAINTEQ--LQSGKTEITELRRTIQ---SLEIDLQS
QLSTK---AALEGTLADTEARYGTQLAQLQLLISGV-EEQLAELRCDMERQ--NHEYRAL
LDVKSRLEQEIA----TYRRLLEGEDAHMSSHYISQ------------------------
P-----VKEGPVTTRQIRTI----FE------------EVQDG--KVISSREQIT--QA-
--------------------------------AH--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTLLH-TS-S---T----------AFGGS--
ST------------------------RGGSFR-------AGG-G-GFGVGSLSG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------M-SCGFGGGVGSGFGG-------------G-FG-------
-GGFGGAFGGGF------------------------------------------------
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIREWYQKQSPTS--
---PERDYSPYFKIISELRDKILAAAIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELAMRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEDLAYLKKNHEE----
-EMKEFSNQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAIAEK-NRREAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITELRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLISSI-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AAIGFREGSL---GGGSSSS----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RFQSSS-------TSYGG-GFGAGSCQL------
-----------------GG--------------GRKISTCSSRFASGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
GGSYGGGFGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLANYLEKVRALEAANADLE---VKIRDWHLRQSPTS--
---PERDYSAYYKTIEELRVKILEATTDNN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---QWFQNK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRRTLQ---SLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFNNSGGTST--ASNASSS----------
-------P------STSG---------------------R-------L-----DFRKY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
NGSRHVCLSSG--AGSVRAPNG---G-AGFAGSSACGG-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSQGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTINANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------VGEAL---------------------
----------------------------PVSASLQQQISHDAGAATSARNQLTEMRRTLQ
TLEIQLQSLMAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGN----SCSKSKGFGSGSPGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNSKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MQNLNDRLASYLDKVRLLESENAELE---CRIREWYAKVGPSC--
E--P-RDYSCFHKEIEDLQNQILCAAMETN------------KILLNIDNSQM-TAEDFR
A-KY-ETECSLRQNVDADICNLRPVLDQLASCKADLQLQCEAVTEEMCCLRANHEE----
-EMSCLRKQA-TGDVSVEVNACPGPDLRKILEELRCQYETLMER-NRKETE---QWFACK
----------------VEEVN-LEVITSSQE--IESSNKQVTELRRQLQ---GLEINVQA
QLTMK---ENLESSLAETECRYNKYLSELQSQISCV-EQRLAEIRAEMECQ--NQEYKSL
LDVKCRLEQEIH----TYRCLLEGGQQDIMYAG-CKQS----------------------
---------------------R---AQ---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MFCSAQRGSCS-------SRVSS-----------SSGA-T
---------------GSRVWAGGSHF-SSGGSCGLGGGS----SWGFQGSS-G-----S-
----------------------CGLGGGSKGGFGSG-------------------AGGGF
GSCVVK--GGFGAVSG-----------------FGGGS----------------GFGGGS
G--------FGGSSGFGG---GSGFGGGCSGG----FSSYGG--S-----MGGGLG-G-V
GGSDGGLLSGSEKQTMQNLNDRLASYLDKVRALEEANTDLE---TKIKEWYGKHGSG--K
GEAG-RDYSRYWPVMEDLKNQIISATVENA------------RMTLQVDNARL-AADDFR
M-KY-EHEMHLRECVEADINGLRKMLDDLTMTRSDLEMQIESLTEELVLLRKNHEE----
-EMKCTQGSS-GGDVTVEMNAAPGTDLTKLLNDMRTQYEALAEQ-NRQEAE---KQFNER
----------------SASLQ-AQISTDAGA--ADSAKTEITELRRTVQ---ALEIELQS
QLALK---CSLEGTLADTQAGYMAQLSGIQTQISNV-EEQLSQIRGETQCQ--NAEYECL
LNIKTRLEEEIE----TYRRLLNGEGGGC-------DYRNLVSSH---------------
-----------------------------------------------------------V
V-----------------------------------------------------------
---------------------------------------------------LSD-MS-GS
C----SGQRKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQVSNI----SEVRIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLCQRLSS---Q-S----VLAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGP---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-SDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGA---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGGGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRTLEEANTELE---NKIREWYETRGTGTGD
A-SQ-SDYSKYYPLIEDLRNKIISANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHED----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEITDLRRAFQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRLS
SGSRRSYSRPSTGS--L----R---G-ASFGAGNACGI-PGIGSGF-SCAFGGSSSSGGN
A------------------GAGNSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQITEDVGATTSARNELTEMKRTMQ
TLEIELQSLLAT----KHSLECSLTETEGNYCSQLAQIQAQVGALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSGGYKSKDYGSGNVGSQMK-DPAKAIVV
KKVLEEVDQRSKILTTRLQSLEEKSHSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAVS----------SFGGL--
-G-------------------------GGSVR-------FGSGG-VFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRIVSS-SSGS--------
------------------------------------------------------------
-----------YGGGYGG-----SFGG----T--------------------------L-
-PVSDGLLAGNEKLTMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIENLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSAPGMDLAKILSDMRSQYEVMAEK-NRKDAE---ALFITR
----------------SEELN-KEVAVHTEQ--LQVTKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYSAQLSQIQAVISSI-EAQLSNVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKA---I------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G----------------------GSSR------------------ASCRLS-----
---------------GSLGG----------GSCRL-------GTA-----SGLG------
--------SGLGS-GLGGGSSFSSCYSFGSGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEAANSELE---VKIRDWYQRQAPGP--
---A-PDYSPYYKTIEDLKSKILVASVDNA------------NVLLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSGKSEISELRRTLQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------AGISS---S-------RA----
---------------------------SGSKQSAVRGSS----AWGFQGRG-S-----S-
----------------------CSF-------------------------------GGGL
RGGSVG--GRWGAGSG-----SGAGFGKGSC-----------------------------
---------FGGGSGFTG---VSGFSVGTGGG----LCSYRGG-------MGGGFG-S--
GMGDGGLLSGNEKLTMQNLNDRLASYLDKVRALEEANTDLE---NKIKQWYDKFGPGSGD
GGSR-RDYSNYYRILEDLRKQIAAAAVENA------------RIILQIDNARL-AADDFR
L-KY-ETELALHQGVEADINGLRRVLDELTMTRSDLEAQIEGLQEELICLRKDHEQ----
-EMKSVLGSC-GGDVTVAVDAAPGTDLTKLLNEMRAQYEQLAEQ-SQQEAE---ERFLEQ
----------------STSLQ-AQISTDAGA--ASSAKKEIAELKRALQ---GLEIEFQS
QLAMK---SSLERTLADTEAGYGAQLSGIQAQIGSL-EEHLCQVRAETECQ--DREYGLL
LDIKTRLEAEIE----TYRRLLHGEGSGSG-FERSRN-----------------------
-----------------------------------------------------------L
D-----------------------------------------------------------
---------------------------------------------------LSHSR----
P----DHPERDSGK-------T-----------------RVTK-----------------
---------------TIIEEVVDGKVISSQVSSI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MALSVRSSAGPRQFSS---R-S----GLGGG--
---------------SLRMSGG--------STGGGFGG-----GLGFGA---G-----S-
AAGFGA-A---SV--LGSG----FGGG-----FGSS-------------------AGSGF
-----G--GGFVSGSG---GGYGSGSG----SGFGGGL----------------G-----
-------------SGFGSG-SGVVFGGGFGSGAAAG--------------FGGGF--GVG
GGGDGGLLSGSKKETMQNLNDRLAAYLDKVRSLEDANTELE---RKIREWYEKNGPGAAV
PGSG-NDYSKYYPIIEDLRNKIINATIDNA------------RIILQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTRADLEMQIESLNEELAYLKKNHEE----
-ELQGLQSSA-VGQVSVEMDAAPGIDLTKLLNDMRGQYEVIAEQ-NRKEAE---AWFNEK
----------------SGELK-REISTNTEQ--LQSGKSEITDLKRTLQ---NLEIELQS
QLAMK---KSLEDTLAETEGGYCAQLSQMQLQIGNL-EAQLLQVRADMERQ--SAEYQQL
LDIKSRLEMEIE----TYRRLLDGEFVGGGQGVVFESSSLTGPKSQ--------------
----------------------------------------TQSL-DS------------S
Q-----------------------------------------------------------
------------------------------------------------------------
----------DPTK-------T-----------------RKIK-----------------
---------------TIVEEVVDGKVVASHVKEVEE------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------ASCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLA------
------------S-ALGS-NSYSSCYSFGTGS----------------------------
--------------GYGS-----SFA----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSSYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLISSV-EEQLGQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL-S---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------ASCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLA------
------------S-ALGG-SSYSSCYSFGSGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLATYLDKVRALEEANTELE---IKIRDWYQKQAPGP--
---A-RDYSHYYQTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL-Q---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------GAGY
T--------CSLGGSFGG-----GLGGG------------------------------F-
GG-GDGLLAGGEKATMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPGP--
---A-RDYSAYYLTIEDLKNKILTATVENA------------NILLQIDNARL-AADDFR
T-KY-ETELALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRVLSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------VT------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------MIFCSP-----G---TLQLHIDKV-NISQNTM-----PLRFS
NGSRHVCLRSG--AGSVRPPNG---G-TGFAGSSACSS-SVTGSEF-SCALGGGLG----
----SVPGGSHAGGA----FGNAACVGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTANANV
ILQIDNARLAA-DDFRLKYENELTFHQNVEADINGLRRVLDELTLCKTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATSSARSELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MSTYSLKQITS-----S----------GLGNF--
-S-------------------------GPSAR-------RAVGF--FGTPSVHG------
---------------G-SG--------------GRDISVSTARFVSSGFGGGLG------
------------AG------YDGGSYSS--------------------------------
-------FS----GGFGG------------------------------------------
---GDGLLSGNEKTTMQNLNDRLASYLDKVRALEEANSDLE---IKIRDWYQKQGP-G--
---PAHDYSLYYKTIEDLRDKILAATVDNS------------KVILQIDNARL-AADDFK
T-KF-ETEMALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELSFLKKNHEE----
-EMNALGGQT-GGQVSVEVDAAPGIDLSKILTDMRDQYEVMAEK-NRKDAE---TWFNNK
----------------TEELN-REVAVNTEQ--LQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLEGTLADTENRYGAQLAQIQQRIGNI-EAQLTDLRADMERQ--NSEYRML
MDIKTHLEQEIA----TYRQLLEGQGSYV-CGSSAPTVC---------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MSCS-------SRLSS---S-------RAGGSS
---------------SARVSAGGSSF-SSGSRCALGGSL----ARGFQGGA-G-----S-
----------------------CGLSGGSSGAFGGS-------------------FGGGF
GSCSVR--GGLGGPSG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFNGGAGGG----FCSYGGG-------M----G-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKFGPGSGD
SGSG-RDYSKYYPTIEDLRNQIIAATVENA------------GILLQIDNARL-AADDFR
L-KY-ENELCLRQNVEADINGLRKVLDDLTMTRSDLEIQTESLTEELAYLRKNHEE----
-EMKTMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELRRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQMQISAL-EEQICQIRGETECQ--NAEYERL
LDIKTRLEMEIE----TYRRLLDGDGGGS-------SFAGFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQERDS---SK----T-----------------RITK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GA-
CGMGG-----------------GSS-RISSVL---------------TGGSYRAP-----
---------------SAYG---------------GLSV-SSSRFSSGGA-CGMG------
--------GGYGGGF----SS-SSSFGGALGGGFGG--------------GYGAGLGGGF
GG----GFGGGFGGGLGA-----GLGGG------------------------------Y-
GG-GDGLVGGSEKITMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQKQRPAE--
---T-RDYTPYFNTIEDLRNKILMSTVDNA------------NVVLQIDNARL-AADDFR
G-KY-ETELNLRMSVEADINGLRRVLDELTLARSDLEMQIESLKEELAYLKKNHEE----
-EMNALRGHV-SGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKEAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMISGV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------S----------SQ--FSSGSQSSR-
--------DVTSSSRQVRT-K---VV------------DVHDG--KVV------S-----
---------THEQ---------------I--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------TIFCSSLKLQ--------PSTGKV-KDPLPAM-----SLRFS
TGSRHICLRSG--TGSARPSNG---G-AGFAGNNACGN-SLTGSGF-SCALGGGLG----
----SIPGGNHPGGI----LGNAAGAGFAGSDGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKSWYEKYGP-GSCRGLDQD---YT-RYHLSIADLKTKIIASTTANANV
ILQIDNARLAA-DDFRLKYENELSLHQNTEADINGMRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX----KHSLECSLTETEGNYCTQLAQIQGQIGALEEQLHQVRTETEGQK
LEYEQLLDLKLHLEKEIETYCRLIDGDGN----SCSKSKGFGSGSSATSSK-ELSKTTLV
KTVVEEIDQRGKVLSSRVHSIEEKTSKMTNGKT--EQKVPF---------

------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDADAATSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLEGSLAETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYKHLLDIKVHLEKEIETYCHLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------RNIDQSNMSCL-------SRVS----S-------RAGGSS
---------------CARASGGGSSF-SNSSRCGFGGGS----ARGFGGS--S-----T-
----------------------CGLGGG--SGFGGG-------------------FGSGF
SSSSVV--GGYGSGSS-----SGAGFGGGSSGGF--------------------------
----------------------YSYGGGVGGG----AG--GGG-------FGG-------
-AGDGGLLSGSEKQTMQNLNDRLASYLDKVRALEEANTDLE---IKIKEWYDKFGPGAKD
SGSG-KDYSHFYPVIEDLKNQIIAATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLRQSVEADTNGLRKVLDDLTMARSDLEMQIESLTEELAYLKKNHEE----
-EMKNMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEDLAEQ-NRKEAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---GLEIELQS
QLAMK---SSLEGTLADTEADYVAQLSQLQMQISSL-EQQICEIRGEMECQ--NAEYEQL
LNVKTRLEMEIE----TYRRLLDGEGGDSH-------SGGSNSW----------------
---------------KS----G--------------------NR-GS------------S
S-----------------------------------------------------------
---------------------------------------------------GGDSRC-GS
S----SGQGKDSNK-------T-----------------RVTK-----------------
---------------TIVEEVVNGKVVSSQVSNV----SEVKVK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSHQFTSS-SSMKG--------SCGIG----
----G-----------------GSG-RISSVL---------------AGGSCRVP-----
---------------STYGG---------------LSV-SSSRFSSGGA-CGIG------
--------GGYGGGF----SSS--SFGGALGGGFGG--------------GYGGGLGAGF
GGGF------------VG-----GFGGD------------------------------F-
GGVDGGLLSGNEKITMQNLNDRLASYLDKVRVLEEANTDLE---VKIRDWYQRQRPSE--
---T-RDYSSYFNTIEDLRNKIIMATVENA------------QPTLQIDNARL-AADDFR
T-KY-EHELALRQGVEADINGLRRVLDELTLSRSDVEMQIESLKEELAYLRKNHEE----
-DMRALRGQS-GGDVSVEMDAAPGRDLSSILNRMRDEYEQLAEK-NRRDAE---AWFLSK
----------------TEELN-REVASNSEL--VQSGRSEVTELRRVLQ---GLEIELQS
LLSMR---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSSSQST-SGQSYSSR--DV--V--YSSSS--
----------SSSGRQTRPIL---KE------------QVS---------TSFSQSQQS-
------K-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFT
SASRRVGTCGG--AGSVRPSAG---G-PGFGA----------GNGF-PCAFGSSGG----
--N----------------PGSASCSAFVGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPTIEDLRNQIISATTSNASV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQHETLSEE
LTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSATLQQQISDDAGATTSARNELTEMRRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCVQLSQIQAQIGALEEQLQQVRTETEGQK
LEYGQLLDIKVCLEKEIETYCRLIDGEDGACFKS---I-GYGSAGPAHQAK-DSSRTTTV
KTVVEEIDPRGKVLSTRVHSVEEKSTKIN-IKT--EPRMPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-SSSRYSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GYGGGLGAGF
GG----GLGAGFGGGFGA-----GFGGG------------------------------D-
----GGLLSGNEKLTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---V-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMTVEADTNGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDLIGNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNSTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGP---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-SDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T------------------KIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGP---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-NDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------ATTTTIRQFSTS-GSLKG--------LCMPS----
----G-----------------GFS-RVSSVH--------------VGGA-CRAP-----
---------------SFLGT----------GSLGNTSV-TSSRFS-----AGLG------
--------GGYS-------G----GYTCNLGGGFGS------------------------
--------------SFG-------------------------------------------
--VGDALLGGGEKETMQNLNDRLASYLEKVRALEEANTDLE---VKIRDWYKKQGPSP--
---A-RDYSHYFKIIEELRSKILAATMDNA------------SFVLQIDNARL-AADDFR
T-KY-ETELTLRMNVEADINGLRRVLDELTLARADLEMQIENLKEELAYMRKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATSTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---SSLEGSLAETEARYGTQLAQLQGLISSI-EQQLCELRCDMERQ--NHEYKVL
LDVKTRLEQEIT----TYRRLLEGEDAHLATHYSS-SL-------------------ASQ
P-----TREASVTSRQVRTI----VE------------EVQDG--KVVSTREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----S-STS----------SFGGL--
-G-------------------------GASVR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----I------------------------------------
LATSDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLRDQILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-ELSVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------SEELN-REVAVHREQ--LQMSNTEVSDLRRTLQ---GLEIELQS
QLSMK---AGLESTLAETEARFGAQLAEIQARISGI-EAQLGDVRADSERQ--NQEYHRL
LDVKSRLEQEIA----TYRSLLEGQEDRY-NNLSASKVLE--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLG------
------------S-ALGS-NSYSSCYSFGTGS----------------------------
--------------GYGG-----NFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSAYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------PYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLRKNHEE----
-EMNSMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEX-XXXXXX---XXXXXX
----------------TEE-L-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGGV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLASSF------------------SSGSQSHR-
--------D---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------STYG---------------GMSV-TSSRFSSGGA-CGIG------
--------GGYGGSF----SS--SSFGGGLGSGFGG--------------RF-----DGF
GGGFGGGLGGGFGGG---------LGGG------------------------------I-
---GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANSELE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KF-ETEQSLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSS-SQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR-------------------SCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLA------
------------S-ALGS-NTYSSCYSFGTGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSSYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLP
SGSRRSCPRPTT--GSLRLSGG---G-ASFGAGNACGI-PGIGSGF-SCAFGGSSTSGGN
A------------------GGGNLYAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEQFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIVVSTTSNANV
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KQSLECSLTETESNYCAQLAQIQAQLGALEEQLHQVRTETESQK
LEYEQLLGIKVLLEKEIETYCLLIGGDDGACKSGGFKSKDYGSGNMGPQVK-DSPKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQFSS---SRS----GGGG---
-------------------GGGGSSLRISSSKSS-------------HGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG-------------------------
----------FGGGSF---GG---GYGGS---SFVGSCG-------------GGGYG---
-GGGFGGGSFGGG-SFGG----GGFGG-------SGF--------------GGGIG-GGY
GGDGGGLLSGNEKAAMQNLNDRLASYLDKVRALERSNYELE---GKIKEWYEKYGNS--S
QREP-RDYSKYYQTIEDLKNQILTLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLSKADLEMQIESVTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQMLDNMRSQYEQLAEK-NRKDVE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLEGEGRGWGKGGGEGSG-----------GGRGGG-----
---------------SYGGG--SS---GGGSHGGSYGGGSSG-G----------------
-----------------GGGSYGGGSSGGSHGGSSGGGYGGGSSGGGG------------
-----HGGSSGGGYGG-G----------------------------SSSGGFKS--S-GS
GGD---QSSKGPRSAEINWGNL-----------------N--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----TSAMS----------SFGGT--
-G-------------------------GGSVR-------IGSGG-VFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRFVTS-SSGS--------
------------------------------------------------------------
-----------YGGVRGG-----SFSG----T--------------------------L-
-AVSDGLLSGNEKITMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYNHYFKTIEDLRDKILGATIDNS------------KIVLQIDNARL-AADDFR
T-KF-ETEHALRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEE----
-EITALRSQV-GGQVSVEVDSTPGVDLAKILSEMRSQYEIMAEK-NRKDAE---ATYLAR
----------------IEELN-TQVAVHSEQ--IQISKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYGVQLSQIQSVISGF-EAQLSDVRADIERQ--NQEYKQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKA---I------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
SSSRRVSSCGG--AGSVRLSSG---G-AGLGAGNICSV------------FGSSSSGGGY
GGG----------LG----GGSSSCAGFMGSEVGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKYGP-GSCRGLDHD---YS-RYFPIIEDLRNEIIAATISNASV
VLQNDNARLTA-DDFRLKYETELALHQSVEADINGLRRVLDELTLCRTDLEIQAETLNEE
RTYLKK--NHEE----------------------EMKVLQCTAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARSELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCVQLSQIQAQIGALEEQLQQIRTETEGQK
LEYERLLHIKVSLEKEIETYCLLIDGDEGICKSGGHKSKDYG---SGSQAK-EPGKAIVV
KKVLEEIDQRSKVLTTRLQSLEEKTPSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCL-------ARAA----A-------RSGGSG
---------------SVRMSGGGSSF-SSGSRCGMGGGS----AYGSGGA--G-----S-
----------------------CRMGGGAGGGFGGS-------------------FGGGC
GSSVVG--GGFGGGFG-----SG--FGGGAGAGFGGGH----------------GA----
----------GAGGGFSG---SCRMGGGAGGG----FG--G-S-------FGGGC--G-S
SVVGGYLFSGGEKQTMQNLNDRLASYLDKVHALEEANTDLE---VKIKQWYEKFGPGSTV
PGSG-RDYSKFYPIIDDLRNKIMAATIDNA------------GMVLQIDNARL-AADDFR
L-KY-ENELYLRQSVEADINGLRKVLDDLTMTRSDLEMEIESLTEELAYLKKNHEE----
-ELKGMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEALAEQ-NRKEAE---DQFNKQ
----------------SASLH-AQISTDVGA--ASSAKSEITELKRTLQ---ALQIELQS
LMTMK---SSLEGTLAETESGYVMQLSQIQHQISSL-EEQICQIRGETECQ--NAEYEQL
LNIKTRLEMEIE----TYRRLLDGEAGGSGLA-SSSTSS---S-----------------
-------------------------------------------L-GG------------G
S-----------------------------------------------------------
---------------------------------------------------RSSVVV-DS
R----VGQGRDANK-------T-----------------RVTK-----------------
---------------TIVEELVDGKVVSSQVSNV----SEMKVK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------MASTTSVRQFSTS-GSVKG--------LCAPG----
----M-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SLVGG----------GSCGNMSV-TSSRFS-----AGLG------
--------GGYG-------G----GYTCSLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGSEKETMQNLNDRLATYLDRVRALEEANADLE---VKIREWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------ASQ
P-----SREGMVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
SASRRL--------GSVRLSSA---G-TALGAGNACGV-PGIGSGF-SCAFGGSSS----
----------AGGLG----LGSTSCGAFTMNEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRAQIISATANNANI
VLQNDNARLTA-DDFKMKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLTEE
LAYLKK--NHEE----------------------EMQALQCAAGGXXXXXXXXXXXXXXX
XXXXXXXXXXXXLAEQNRRDAEA--WFQEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCRLIDGDEG----SCVKSKG--QGGPGNQTK-DSSKTAII
KTVVEELDPRGKVLSSRVHTLEEKSTKVNKNE----QRTS----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MFCSAQKGSCS-------SRVSS------------SGA-V
---------------GSRGCTGGSSF-GGGSSCGLGGGS----AWGFQGSS-N-----S-
----------------------WSLSGGSKGS-----------------------MGGGF
GSCSVR--GGFGAASS-----------------YGGGS----------------GFGGSS
G--------FGGGSGFGG---GSGFGGGSSGG----FSSYGG--S-----MGCGLG-G-V
SGYDGGLLSGSEKQTMQDLNDRLANYLDKVRALEEANTDLE---CKIKDWYGKHGSV--K
GGSG-RDYSQYYSIIEDLKKQILSATCENA------------RMTLQIDNARL-AADDFR
M-KY-EHELCLRECLEADINGLRKVLDEMTMTRCDLEMQIEGLTEELVFLRKNHEE----
-EMKCMQGSS-GGDVTVEMNAAPGVDLTKLLNDMRAQYEAMAEQ-NRQEAE---RQFNER
----------------SASLQ-AQISSDAGE--ANCARSEVMELKRTVQ---TLEIELQS
QLALK---CSLEGTLADTEAGYVAQLSGIQAQISSL-EEQLSQIRAETQCQ--SAEYECL
LNIKTRLEQEIE----TYRRLLNGDGGGC-------DYRNLVSKN---------------
-----------------------------------------------------------V
V-----------------------------------------------------------
---------------------------------------------------LSD--S-GS
C----AGQGKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGRVVSSQVSNI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAVS----------SFGGL--
-G-------------------------GGSVR-------FGSGG-VFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRIVSS-SSGS--------
------------------------------------------------------------
-----------YGGGYGG-----SFGG----T--------------------------L-
-PVSDGLLAGNEKLTMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIENLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSAPGMDLAKILSDMRSQYEVMAEK-NRKDAE---ALFITR
----------------SEELN-KEVAVHTEQ--LQVTKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYSAQLSQIQAVISSI-EAQLSNVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKA---I------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQSSS-T---S----------SFG-G--
MG------------------------GGSVRF-------GAG-G-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS-GGYG------
------------GG------YA--------AGGFGG-------------G-AG-------
-SGYGGGFGGGFGGGFGS-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWYQRQSPTS--
---PERDYSPYFKTTDELRDKILAAAIDNS------------RVILEIDNARL-AADDFR
L-KY-ENEMALRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQL-AGQVNVEMDAAPGVDLTRVLSEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKSEITDLRRTIQ---GLEIELQS
QLSMK---AGLESTLAETECRYAAQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYHSLLEGQDARM-AGIGTGEASL---GGGGG------------
--------------GKVRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----S-STS----------SFGGL--
-G-------------------------GGPVR-------FGPGV-AFRAPSIHW------
---------------G-SG--------------GRGVSVSTTRFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----I------------------------------------
LATSDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTNQDLRDQILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRVSVE--------VLDELSLARTDLEMQIEGLKEELAYLKKNHEE----
-ELSVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAVHREQ--LQMSNTEVSDLRRTLQ---GLEIELQS
QLSMK---AGLEGTLAETEARFGAQLAEIQARISGI-EAQLGDVRADSERQ--NQEYHRL
LDVKSRLEQEIA----TYRSLLEGREDRY-NNLAPTQT----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCP-------ASFSS---S-------RA----
---------------------------RGS--CVLGGNS----AWGSQGG----------
----------------------------------------------------------GF
GSCSGG--GRWGAGLG-----SGAGFGKGSY-----------------------------
---------FGGSSGFAE---VSGFSSGASGG----FCSYGGG-------MGGGFE-G--
GVGDGGLFSGSEKQTMQNLNDRLASYLDKVRALEEANTDLE---NKIKGWYDKFGPGSRD
GGSR-RDYSNYYSILEDLRKQIVAATVENA------------GTILQIDNARL-AADDFR
L-KY-EHEQSLRQSVEADISGLRRVLDGLTMTRSDLEMQIESLQEELVILKKNHEE----
-EMTSVRGSR-GGDVTVEMNAAPGTDLTKLLNDMRAQYEQLAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDVGA--ASSAKTEITELKRTLQ---ALEIELQS
QVAMK---SSLQRTLADTEAGYGAQLSGIQVKISSL-EEQICQVRAETECQ--NREYELL
LDIKTRLEVEIE----TYRRLLNGEGRLAL-VLKDPG-----------------------
-----------------------------------------------------------T
C-----------------------------------------------------------
------------------------------------------------------------
V----TPWFSDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGRVVSSQVSSI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYG---------------GLSV-SSSRFSSGGA-CGIG------
--------GGYGGGF----SSS-S-FGGGLGSGFGG--------------GFGGGIGSGF
GG-------GSFGGGFGG-----GLGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELTLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMASMKGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLSQIQEMISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-STQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAIS----------SFGGL--
-G-------------------------GGSVR-------FGSGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARIVSS-SSGS--------
------------------------------------------------------------
-----------YGGGYGG-----SFGG----T--------------------------L-
-AVSDGLLSGNEKITMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIEDLRDKILGATIENA------------RIVLQIDNARL-AADDFR
T-KF-ETEQTLRQGVEGDINGLRRVLDDLTLGRTDLEMQIESLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTTR
----------------TEELN-REVAGHTEQ--LQMSKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYGAQLSQIQGVISSI-EAQLSDVRADTERQ--NQEYQLL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKA---I------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRISS---S-------RAGGSC
---------------SVRVSAGGGSF-SSGSRCGLGGGS----TRGFRGGA-S-----S-
----------------------CGLSGGSSGG-----------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSG-----------------------------
---------FGGGSGFCG---GSGFGGGASGG----FYSYGGG-------MV-----G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANADLE---NKIKEWYDRYGPRSRD
GGSG-RDYSKYYPIIEDLKNQIVTATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELHLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EIKSMQGSS-RGDVTVEMNAAPGTDLTKLLNDMRAQYEALAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKSQITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQMKISSL-EEQICQIRAETECQ--NTEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-CFSGS-DFRNSGSRNT--------G-----
------------S-KNS----G--------------------SR-DS------------S
------------------------------------------------------------
---------------------------------------------------SCDSRS-GS
H----SGQGRDP---TK----T-----------------RVTK-----------------
---------------TIIEEVVDGKVISSQVSNV----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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-------------SA----IGNAVFAGFAGNDGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKSKVISSTAANANI
ILQIDNARLAA-DDFRLKYENELALHQNVEADINGLRRVLDELTLCRTDQELQFESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVDVQMNAAPGVDLT
LMLNNMRAEYEALAENNRRDAEA--WFNEKSATLQQQISDDAGAATSARSELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAHIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGDGDSCS----ISKGFGLGGSGNSTK-DVSKTTLV
KTVVEEIDQRGKVLSSRIHAIEEKTSKMANGKA--EQRVPF---------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SMRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGTGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RFQSSS-------TSYGG-GFGAGSCQL------
-----------------GG--------------GRKISTCSSRFATGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
GGSYGGGFG----GGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEAANADLE---VKIRDWHLKQSPAS--
---PERDYSAYYKTIEELQVKILEATTDNN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIETLNEELAYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFQTK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQELISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSKM-TGFNNSGGNGSTSTSNASSS----------
-------P------STSG---------------------R-------L-----DFRKY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RFQSSS-------TSYGG-GFGAGSCQL------
-----------------GG--------------GRKISTCSSRFASGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
GGSYGGGFGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLANYLEKVRALEAANADLE---VKIRDWHLRQSPTS--
---PERDYSAYYKTIEELRVKILEATTDNN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---QWFQNK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRRTLQ---SLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFNNSGGTST--ASNASSS----------
-------P------STSG---------------------R-------L-----DFRKY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQYSS---SRS----GHGG---
--------------------GGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSAGGCLGGSSI-VYGGG-------------------LGGGF
GG-------GY-------------------GSNFGGSYG-------------GGSFGGGY
GGGSFGGGSFGGG---------------SFG---------------------GGLG-GGF
GG-DGGLISGNEKITMQNLNDRLASYLDKVRALEESNYELE---VKIKEWYEKHGNS--S
QREP-RDYSKYYQTIDDLKNQILNLTTDNA------------NILIQVDNARL-AADDFR
M-KY-ENEVTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEK-NRRDAE---AWFNEK
----------------SKELT-TEINSNLEQ--VSSHKSEITELRRTIQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGSYGGGRSG--G------------------
----------------YGGSSGGGGGYSGGSSSGGYGGGSS-------------------
--------------------------SGGYGGGSSSGGYGGGSSSG--------------
---GGHGSSSGGGYGG-GSSSGG----------GHGSSSGGGYGSGTSSGGHKSTTS-GS
VGE---SSSKGPRSAETSWGNQ-----------------N--------------------
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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSAYGG-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTLQNLNDRLATYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RCHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLA
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDSGAATSARSQLTEMRRTLQ
TLEIQLQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCHLIDGDGNSCS----KSKGFGSGSPGNSSK-DLSRTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

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-------------------------------------------------M-----SLRFS
SGSKRSGARAST--GSLRLSSG---G-ASFGAGNACGT-PGIGSGF-SCAFGGSSS-VAN
S------------------GPSTHYAGFPLSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELEVKIKGWYEKFGP-GSCRGLDQD---YS-RYFTIIEDLKNQVIASTTSNANT
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLSETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDEGACKSGGYKSKDFGASIMGNQIK-DPIKAIVV
KKVLEEVDQRSKVLTTRLHSLEDKPQNS----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------M-SCGFGGGG------------------------------
-------AGGGFGGGFGG-----SFG--------------------------------DF
GSSDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQSPSS--
---PERDYSPYYKTIEELRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-EE-LALRQ-SEADINGLRRV-DELTLARTDLXXXXXXXXXXXXXXXXXXXX----
-EMKEFGSQL-AGQVNVEMDAAPGVDLSRMLAEMREQYEAMAEK-NRRDAE---AWFFTK
----------------TEELN-KEVASNTEM--IQSSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGLISSL-EAQLSELRCEMEQQ--NQEYNRL
LDIKSRLEQEIA----TYRSLLEGQDAKM-ANVGIREVSL---GGGGS------------
-------------SSGFRVHIE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
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--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYG---------------GMSV-SSSRYSSGGV-CGMG------
--------GGYGGGF----SSS--SFGGGL--------------------------GSGF
GG----GFGGGFGGGLGS-----GFGGG------------------------------L-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMREQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVTTNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLSQIQDMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKCRLEQEIA----TYRRLLEGEDAHL------SS---------AQ--FSSGSQSSR-
--------DVSSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
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---GDGILPAGEKETMQNLNDRLAAYLDKVRALEDANTDLE---VKIREWYKKQGPG---
---PDRDYSPYYRTIEELRSKVLVATVDNA------------NLLLQIDNARL-TADDFR
T-KY-ETELALRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEE----
-EMNCLRKQS-TGDVSVEVNACPGPDLRKILEEMRCQYETLIER-NRKEVE---DWYECK
----------------IEEVN-REVITSGQE--VETCNNQVTELRRQLQ---ALEIDLQA
QLSQI---DSLQSNLDDTERRYNMQLQQIQSMISPL-EEELASIRCEMESQ--NQEYKML
LGIKTRLEQEIA----QYRSLLE-------------------------------------
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--------------------------MTSCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG---------------LSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GYGGGFGGGF
GGGF-G-------AGFGA-----GFGGG--------------------------------
----DGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPTE--
---V-KDYSPYFRTIEDLKSKIITATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELAMRQSVEADINGLRRVLDELTLARTDLQMQIESLNEELAYLKKNHEE----
-EMLAMRGQT-GGDVSVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQGMISSV-EEQLA------------------
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---------------------------MSCS-------ARISS---S-------RAGG--
----------------YRMSGGGNSL-SSGSRCGLGSGS----A--------S-----S-
----------------------WGLSGGSSGGFGGG-------------------IGGGF
SSCSVR--GGSGAASG-----SRAGFGWGSG-----------------------------
---------------FGG---SSGFGSGASGG----FYGHGYG-------LGGSFG-D-S
DISDGGLFSGSEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKNG--SRN
SGSR-RDYSKYYSVIEDLKNQIIAATVENA------------GIILQIDNSRL-AADDFR
L-KY-ENELFLRQSVEADINGLRKVLDELTMTRSDLEMQFESLTEELAYLRKNHEE----
-EMKSLQGSS-SGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEK-NRREIE---EQFNKQ
----------------SASLQ-SQISVDAGA--ANSAKNEITELKRTMQ---ALEIELQS
QLAMK---SSLEGNLANTEAGYAAQLSKTQMLINSL-EEQICQIRGEAECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGPSK-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQVSNI----SEVKI-----------------
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--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGGIG
GGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF------SSSS------------------------SSFGSGFGGGY
GGGLGAGFSGG----LGA--------GL---------------------------G--GG
FAGGDGLLVGSEKVTMQNLNDSLVSYLDKVRALEEANADLE---VKIHDWYQWQRPAE--
---I-KDYSPYFKTIEDLRNKVASSFWEQY------------MPQA----ADT-LRFLYR
T-EY-ETELNLRMSVGADINGMRQV--------ADLEMQIESLKEEL-------------
-EMNALRGQV-GGDVNVEMDAAPGVDLSHILNEMRDQYEKMAEK-NHKDAE---ERFFTK
----------------TEELN-HEVATNSEL--VQSSKSEISELWRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCVQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKMRLEQEIA----TYHRLLEGEDAHLSSSQFFSGS--QSSR--D-------------
-------------RRQIRTK----VM------------DVHDG--KVVSTHEQVLRTKN-
------------------------------------------------------------
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----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSAGGYG------
------------GG------V-SCGFGGGAGSGFGGGYGG------GL------------
GGGYGGGLGGGFGGGFAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYYKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSSAGSVSPRSTSVTTT----------
-------S------SAS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
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-------------------------MATTTIRQYTTS-SSIKG--------SSGLG----
----G-----------------S-----SSR------------------ASCRAP-----
---------------G-SFGS--------ASSSRL-------VSG-----GSLG------
--------GGYG------GSSYSSGYSFSSGM----------------------------
GG------------SYGG-----SFG----------------------------------
--SVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTDLE---LKIRDWYQKQAPGP--
---A-RDYSAYHQTIEDLKNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KY-ETELALRTSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHDE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRTLSEMRDQYEKIAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--LQSGKSEISELRRSVQ---ALEIELQS
QLSMK---ASLEGSLAETESRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSQY----------------------------
------KPKEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH--Q--
-----------------------------------STR----------------------
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------------------------MATTTTVRQYSTS-GSMKG--------LCGLG----
----P-----------------ASS-RVSSVR--------------VGGA-CLAP-----
---------------SLLGA----------GGCGNMSV-TSSRFT-----SSL-------
-----------G-------GGYGGGYSCSLGGGFGA------------------------
---------------------------S------------------------------YG
--VGDALLGGSEKETMQNLNDRLANYLDKVRALEEANTDLE---LKIRDWYKKQGPGP--
---A-RDYSAYFKTIEDLRNKILAATIDNA------------SLVLQIDNARL-AADDFR
T-KY-ETELNLRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNTEA--LQSSKTEITELRRTVQ---NLEIELQS
QLSMK---ASLEGTLAETEARYGAQLAQLQGLISSI-EQQLCELRCDMERQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLASQYSS-TL-------------------SSG
S-----GREAMVTSRQVRTI----VE------------EVQDG--KVVSSREQLH--RS-
--------------------------------TH--------------------------
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--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGP---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGL---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-NDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCTQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------------MTTCSRQFTSS-GSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------SAYGG---------------LSV-SSSRFSSGGA-CGLG------
--------GSYGGGF----SSS-SSFGGTLGSGFGG--------------GYGGGLG---
-------------AGFGG-----GFGAG------------------------------F-
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQQPSE--
---A-KDYSPYFRTIEDLRNKIIAATVENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVTELRRVFQ---SLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQGLIDSV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLP-SQH-TSGQS-Y-SSREV--YTSSS-----
----------SSSGHQTRPIL---KE---------------------QGSSSFSQGQSS-
------KH----------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRPCPRPTT--GSLRLSSG---G-ASFGAGNACGI-PGLGSGF-SCAFGGS-SSGGN
V------------------GGSNSCASFTLNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKYGP-GSCRGLDHD---YS-RYFPIIEDLKNQIITSTTSNASA
VVQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMKVLRCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARSELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGDDGACKSGAFKSKDYGSGNVGNQGK-DPTKALAV
KKVLEEVDQRSKILTTRLHSLEEKSQNN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------G------SR------------------TSCRLA-----
---------------GSLSG----------GSCRL-------GSA-----SGLG------
--------SALG-----GSSSFSGCYSFGSGGSYGS--------------A---------
---------------YGS-----SSG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKRAPGP--
---A-PDYSHYYKIIEDLNNKIITASMDNA------------NILLQIDNARL-ASDDFR
T-KF-ETEQALRMSVEADINGLRRVLDEMTLARGDLEIQIENLQEELAYLKKNHEE----
-EMNSLRSQV-GGEINVEMDAAPGVDLSRILSXXXXXXXXXXXXXXXXXXX---XXXXXX
----------------TEELN-REVATNSQL--VQSGKSEISELRRTLQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQYKPKE------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNSLS---------
-----------------------------LSVRTPGLPRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----TFGFGA---S-----S-
GGGFSA-A---SM--FGSS---SGFGVGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------MGGGGFGGLGMGF---GGSQG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGAGD
A-SQ-NDYSKYYPLIEDLRNKIISASIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTMTRTDLEMQVESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQTSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLDES---LFVTDSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSSTS----------SFGGM--
-G-------------------------GGSVR-------FGAGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SSGG--------
------------------------------------------------------------
-----------YGGGYAG-----ALA----------------------------------
--TSDGLLAGNEKLTMQNLNDRLASYLEKVRALEEANGDLE---VKIRDWYQKQGP-G--
---PARDYSHYFKTIEDLRDQILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVETDINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISMLKGQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSK
----------------TEELN-KEVAGHTEQ--LQISKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLEETEARFGAQLAQIQALISGI-EAQLSDVRADTERQ--NQEYQHL
MDIKTRLEQEIA----TYRNLLEGQDAYY-NDLSLAKA---L------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVQYSS-SKHYSS---SRS----GGGGGGG
-------------------GGRGSSLRISSSKGS-------------IGGGFS-----S-
GGGFSG-G---SF--SRGSSGGGCFGGSLG-GYGG--------------------GLG--
-GG-LG--GGFGGGSF---GG---SYGSS---SFGGGYG-------------GGGFG---
-GGSFGGGSFGGG-GFGG----GGF---------------------------GGFG-GGY
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKQWYEKYGST--S
QREP-RDYSKYYQTIEDLKNQILHLTTDNA------------NALLQIDNARL-AADDFR
L-KY-ENEVALRQSVDADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHDE----
-EMKDFQNVN-TGDVNVEMNAAPGIDLTQLLNNMRNQYEELAEQ-NRKDAE---AWYNEK
----------------SKELT-TEIDSNIEQ--ISSYKTEITELRRTIQ---GLEIELQS
QLALK---QSLDASLAETEGRYCVQLSQIQAQISTL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGSYRGGRGGG--------------------
------------SSGGYGGSSGG--------GGGGYGGSSGG-G-G--------------
-GGGFGG--------SSG----GGGGGYGGSSGGGGGGYGGSSGGGGGGS----------
-------GSYGGSSGG-GGSF----------------------GGGS-SGGGLKSSS-GS
TGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VI-GR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGA---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGGSFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTAD
A-SQ-SDYSKYYPLIEDLRNKIISASIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHED----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAFQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------VH----------------------LSSITMS---------
-----------------------------LSVQTSGVSRRSSS---Q-S----GALGR--
---------------ARGMSAS--SA-GSG-----YGGS----ILGFGG---S-----Y-
GGGFYG-A---SM--FGSG---SGLSGGSG------------------------------
------------SFFA---GGLGAGYGGALG-----------------------------
---------------------------GGFGGLGIGF---GGSLG----G--GSP--GVL
SGNDGSLLYGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGSGTED
PGSQ-SDYSKYYPLIEDLKNKIISASIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALRQSVEADINGLRRVLDELTLARADLEMQIESLTEELAYLRKNHEE----
-DLQSFRTDG-PGQVTVEMDAAPGVDLTRLLNDMRAQYEAIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAFQ---NLEIELQS
QLAMK---KSLEDSLAQTEGEYCGQLSQVQQLIGSL-EEQLLQVRADTERQ--NADHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLDESS---SETDSKSQ--------------
----------------------------------------PQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------S-----------------RKIK-----------------
---------------AIIQKVVNDEVVSTQVQELEQLI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRVSS---S-------RAGSSG
---------------MVRVSAGGSSF-SSGSRCGLGGGS----ARGFRGGT-G-----S-
----------------------CGLSGGSTSGFGGS-------------------FGGGF
GSCSGG--GGLGGTAG-----SGAGFGGGSG--FGGGS----------------G-----
---------FGGGSGFGG---GSGIGGGASGG----FYSCGGG-------MGGGMG-G--
GVGDGGLFSGGEKQTMQNLNDRLASYLDKVRALEEANTDLE---NKIREWYEKFGPGSGD
GGSG-KDYSKYYPVIEDLRNQIITATIENA------------GIVLQIDNARL-AADDFR
M-KY-ENELYLRQAVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QMAMK---SSLEGTLADTEAGYMAQLSEIQMKISSL-EEQICQIRGETECQ--NAEYEQL
LNIKTRLEMEIE----TYRRLLDGEGGGC-------GSGGSDLRNS--------G-----
------------S-RST----G--------------------SR-N-------------M
G-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDP---NK----T-----------------RVTK-----------------
---------------TIVEEVVDGKVISSQVSNV----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRVSS---S-------GTGG--
----------------IRVSAGG-RL-GSVGKCGVGGGS----AWGSQRGA-S-----S-
----------------------CGLSGGSTCGFG-----------------------EGL
VSFSGG--GGFGAVSG-------PG--------FGGGS----------------GLGSGT
-------------------------------------GGYGGG-------TGGGLG-G--
GVGNGGLFSGNGKQTMQNLNDRLANYLDKVRTLEDANTDLE---GKIQGWYEKHGPGSTD
GGSE-RDYSKYYKTIEDLKNQIVSDTIKNA------------GTMLQIDNARL-AADDFR
L-KY-EDELCLRQCVESDVTGLRKVLDDLTMTRSDLEMQIESLTEQLTYMKKNHEE----
-EMKSVQGTT-GGDVTVEMNAAPGTDLIKLLNDMRAQYEELAEQ-NRREVE---EQFNQQ
----------------SASLK-AQISADVGA--ASSAKNEVTEARRTLQ---ALEIELQA
QLATK---SSLEGTLADTEAGYVARLLDIQLRIGSL-EEQICQIRDSNKCQ--NAEYEHL
LDVKTRLEAEIE----TYRHLLSGEGGAV-------DYRNSR------------------
----------------------------------------------D------------L
V-----------------------------------------------------------
---------------------------------------------------SGDPRS-RS
G----SGEGRDSNK-------T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQISNI----SEVKIN----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRACPRATA--GSLRLSGG---G-TGFGAGNACSM-PGIGSGF-SCTFGGS-SSGGN
A------------------GGSNLCAGFTLNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNAHA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGEDGACKSGGYKSKDYGSGNMGNQVR-DLAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQNN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSC-LS-----
---------------GGLGA----------GSCRL-------GAA-----SGXX------
------------X-XXXXXXXXXXXXXXXXXX----------------------------
--------------XXXX-----XXX----------------------------------
--XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXX--
---X-XXXXXXXXXXXXXXXXILTATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMSTLRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKIAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLGQLRCDMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------TMS---------
-----------------------------LSVRTSALSRCLSS---Q-G----GATGR--
---------------PKGMSAF--SM-GSS-----LAGS----VFGFGA---S-----Y-
GGGFSA-A---SM--FGAD---AAFGGGSG------------------------------
------------SSF-----------AGGLGSGYGGC-----------------------
------------------------LG-GGFGGLGMSL---GGSTA----G--GSL--YIP
SVGDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYEARGSRSGD
AGLQ-GDYSKYYPLIEDLRNKVISANIGNA------------QLILQIDNARL-AADDFR
M-KY-ENEAALRQAVEADTNGLRRVLDELTLARADLEMQIEGLNEELAYMRKNHEE----
-ELQSCRAGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFMEK
----------------SGELR-KEISTNTEQ--LQSSKSEITDLRRALQ---NLEIELQS
QLAMK---KSLEDSLAETEGGYCSQLSQVQEMVGNL-EEQLQQVRADTEHQ--NADYQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLDEAS---SVSGSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPSK-------S-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVKEVEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSFRSSS-SKHYSS---HIQ----GGRGGGG
-------------------GGGGSSFRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRMSS-GGCLGGSSS-GYGM---------------------SGGF
GGSSFG--GGYA-SSF---GG---GYGGG---SF----G-------------GGSFS---
-GGSFGGGGFGGG--FGG----G-----------------------------FG---GGF
GG-DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--R
QGEP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKTEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGYGGG--------------------
----------------------SS---GG-------------------------------
------------------------------------------------------------
-------------G-----------------------------GGGSSSGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYST-TKQYSS---SRS----GGGGG--
---------------------GGSSHRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSSGGCFVGSSG--YGG--------------------LGGGF
GGGSFG--GGYGSSSC---GG---------------------------------GYGGSF
GGGSFGGGSFGGG-SFG-----GGFGG-------GSF--------------GGGYG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRILEQSNYELE---SKIKEWYEKNSNS--G
QGES-RDYSKYYQTIDDLKNQILNLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--MSSYKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGG-RGGGSSGGG-------------------
----------------YYGG----------SSGGGYGG-----S-S-------GGGHSGS
SG----------------------------------GGYSGGSSGGGGHGGS--------
-------SGGGGGYGG-GSSSGG----------GHSSSSGGGYGGSSSGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----S-STS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSIHR------
---------------G-SG--------------GRGVSVSSTRLVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----I------------------------------------
LATSDGLLAGNEKLTMQNLNDRLASYLDKVRALEAAN-ELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLRDQILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-ELSVLRGQV-GGQISVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAVHREQ--LQMSNTEVSDLRRTIQ---GLEIELQS
QLSMK---AGLEGTLAETEARFGAQLAEIQARISGI-EAQLGDVRADSERQ--NQEYHRL
LDVKSRLEQEIA----TYRSLLEGQEDRY-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------R-IIS-----NMSCKKSCG---SSRIS------VG-
--------------CGGYGTSVCSFLGNSGGVCGT-------------------------
------------PA-------------------YC--------------GSVSGGAAGGL
GGEFGN---------YAA-----GWGTGAAYG----------------------FG----
-VGPEGLLAGGEKETMQNLNDRLAAYLNKVRALEEANSDLE---CKIREWYEKHRNAC--
-MPD-RDYSKYYHIIEDLKKQIQCASVENA------------RVILQIDNARL-AADDFK
L-KY-ENELCLRHGVEADINGLRKVLDELNLAKCDLESQIESLTDEIACLKKNHEE----
-EMKGYQG-A-TGHLSVEMKAAPGNDLTKHLNDMRAEYEELAEK-NRKEAE---ARFNEA
----------------SRALK-QEISCGAEQ--IQCSKNEITDLKRNLQ---ALEIDLQA
ALAMK---KTLECSLAETEGNYCVQLSKIQAKISAL-EQQLCEVRTDMERQ--SIEYEQL
LDIKTRLEMEIE----TYRRLLDGESCFTRV----LKSSLF---------FFSIK-SYPV
PTPK--EFTEPCKTRVIKTIVE----------------DIIDG--KIVSHQVTERKE---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCSIKQ-TT--GSLR--GRTSGGSCVIGGGGG
GGGAR-------------------------------------------------------
------------------I----------YTTCGIGG---SRGFS-GRSYCGGVN-YG--
-------------GGLSSGSLVGGSYGGG---------CS---GIG--------------
------------------------FSGGVVG---------------------------GG
FSGDGILLSGDEKVTMQNLNDRLASYLDKVRCLEQENADLE---CRIREWYAKQGPFC--
E--P-RDYSCYYKEIEDLQNQIVCATIDNN------------KIILNIDNSRM-TADDFR
V-KY-ETELALRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEE----
-EMNCLRKQS-TGDVSVEVNACPGPDLRKILEEMRCQYETLIER-NRKEVE---DWYECK
----------------IEEVN-REVITSGQE--VETCNNQVTELRRQLQ---ALEIDLQA
QLSQR---DNLESSLAETECRYNNHLGELQTQITCV-EQQLADLRAEMECQ--NQEYKIL
LDVKCRLEQEIH----TYRCLLE---------G-GIGQ----------------------
---------------------L---SGLGG-GVARTGGIGGGG--IIRTSHT-YTS----
-----------------SAQMPSC------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------AAAEI-----QGEGTELPWA---SS------------
-PLCWTAMLPEGRRWGREGKD-RARRQARHRQRRTGRKDWSEI-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGG-
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLG-F
GGGSFG--GSYGSSSF---GG---------------------------------LWRGSF
GG--------------------GSFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSYGGG-------------------
----------------YGGG----------SSRSGRATEAVATE-A-------ASLRRRK
LAAALRRA---A-----------------ARRGRPAGGLRGGSSGGG---QQ--------
-------RSGG---------------------------GHGAFGGGA-----RPASA-PS
PPL---LRVRGASLHLRDQGQQ-----------------KLAG-----------------
---------V----IRISFNFL--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EINTLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGI-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSHS-------TRVSS---S-------RAGGSS
---------------SARVSAGGSSF-SGGSRCGLGGSS----ARGFRGGT-G-----G-
----------------------CGLSGGSSSAFGGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSSGASGG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEELRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQVSAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSLSVLSSGLSQRMSE---Q-S----RVAGQ--
---------------ARGLSTSSPVG-G-------PGAS----AFGFGAGGFC-----C-
AGGFSA-A---SV--FGSS---SGFSGAST------------------------------
------------CSLA---RGLGTGHGGPLG-----------------------------
---------------------------GGFRGLGMAF---GDSPA----G--GSA--GIL
GGNDGGLVPGSEKATMQKLNDRLASYLEKVRALEEANADLG---QKIRDWYERQGSGARD
SSSQ-NSYSKYYPLIEDLRNKVLSASIGNA------------QVILQVDNAKL-AAEDFR
M-KY-ESELALHQMVETDIHGLHRVLDELTLPRADLEMQIEGLNEELAYLKRNHKE----
-ELQSIRAKG-PREISVEIDAVPGVDLTRLLNNMRARFEVLTEQ-NRKDAE---AWFVEK
VSTGHSALTLRLSTLQSGELQ-KEISSNTEQ--LQSSRS---------------------
---EK---KSLEDSLAETEGGYCSQLSQVQQLVGNL-EAQLQQVRTNAKCQ--GAEHQRL
LDATARLELEIE----TYRRLLDGEAAGDGLDESS---SVTVSNSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RTIK-----------------
---------------TIVQEVINGEVVSSQVQEIEEVM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-STSRFSSGGA-CGLG------
--------GGYGGGF----SSG-SSFGGGLGSGFGG--------------GFGG------
------GLGGGFGAGLGA-----GFGGG------------------------------F-
GG-GDGLLAGNEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---S-KDYSPYFKTIEDLRNKILVATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSLRGHV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELPRTMQ---SLEIELQS
QLSMK---ASLENSLEETKGRYCVQLAQIQELISGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------A----------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VV------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------TIEQLQNQIISATVDNN------------KMLLDIDNSKM-TAEDFR
M-KY-ENELVIRQTVEADINGLRNLMDDLTLVRSSLESELESLKDELIALKRNHEE----
-EMRQLQSQT-GGDVSVEVNAAPGEDLTKILNEMRDEYEQIIEK-NRREVE---QWYEVK
----------------IQEVN-QQVTSSSQD--IQTSSHQLTELRREMQ---NLEIELQA
QLSTK---TSLENSLAETESRYSCLLQQIQAQINCI-EEELASIRCEMEGQ--SQEYKML
LGIKTRLEQEIQ----QYRALLQEGQQD--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLSG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSVFGG-------------G-FG-------
-GGVGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIHDWYQKQTPTS--
---PECDYSQYFKTIEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIAIREASS---GGGGS------------
-------------SSNFHINVE----------------ESVDG--QV----------VS-
------S--HKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SGSRRSCSRPAT--GSLRLSGG---G-TSFGAGNACGI-SGIGSGF-SCAFGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
ILLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------LG----------------------PSSSTMS---------
-----------------------------LSVRTSGLPQWLSS---Q-S----GTLGR--
---------------ARDMSAS--SI-GSG-----YGGS----PFGFGG---N-----S-
GGGFSA-A---SM--FGSS---SGFGSSSGFGSSSG-------------------FG---
-----------GGSFA---GGLGAGYGGAG------------------------------
--------------------------GGGFGGLGIGF---GGSSG----G--GSV--GIF
PGIDGGLISGSEKETMKNLNDRLASYLDKVRALEEANTDLE---TKIREWYETRGSGTGD
PGSQ-NDYSKYYPLIEDLRNKIISANIANA------------QLILQIDNARL-AADDFR
M-KY-ENELALCQSVEADINGLRRVLDELTLARADLETQIETLNEELAYLKKNHEE----
-ELQSCQAGG-PGQVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIE-
K--------------QSGELR-KEISSNTEQ--LQSSKSEVTDLRRALQ---NLEIELQS
QLAMK---KSLDDSLAETEGDYCSQLSQEQQHMGSL-EEQLLQVRADAERQ--SADYQRL
LNVKARLELEIE----TYRRLLDGEAQGDSLVESS---YVTASTSQ--------------
----------------------------------------TPST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------A-----------------RKIK-----------------
---------------TIVQEVVNGEVVSTQVKEIEELM----------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRLS
SGSRRSCPRPTT--GSLRLSGG---G-ASFGAGNACGI-PGIGSGF-SCAFGSS-TSGGN
A------------------VGGNSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANTDLEQKIKGWYEQFGP-GSCRGLDHD---YS-RYFPIINDLKAQIIAATTSNANA
VLQIHNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGAITSARNELTEMKRTLQ
TLEIELQSLLAT----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNLGNQVK-DAAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKPQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSIL---------------AGGSCRAP-----
---------------STYG---------------GMSV-TSSRFSSGGA-CGIG------
--------GGYGGSF----SS--SSFGGGLGSGFGG--------------RF-----DGF
GGGFGGGLGGGFGGGLGG-----GLGGG------------------------------I-
---GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANTELE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KF-ETEQSLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSS-SQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RFQSSS-------MSYGG-GFGAGSCQL------
-----------------GG--------------GRNISSCSSRFVTGGSAGGYG------
------------GG------M-SCGFGGGAGGGFGGG-----------------------
---FGGGFGGSYGGGFGG-----GFG--------------------------------DF
GGVDGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLE---VKIRDWHLKQSPAS--
---PERDYSAYYKTIEELRIKILEATTDNN------------RIILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFQTK
----------------SAELN-KEVSSNAEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFNSGGNNTTTSNGS-PS-----------
--------------SNSG---------------------R-------P-----DFRKY--
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
--------------------------MSTTVRQFSSS-TSLK-----------GLG----
----G-----------------GSS-RLSCGR----------------AAGYRAP-----
---------------SVH------------GGSSSYSV-SS-RIV-----SGLG------
--------AGYG-------GGYCSSVGGGLGGGFGA--------------SYGAGYGAGF
GG------------GFGA-----GFGGG------------------------------FG
GGD--GILPAGEKETMQNLNDRLAAYLDKVRALEEANTDLE---VKIREWYKKQGPGP--
---E-RDYSPYYRTIEELRSKILAATVENA------------NIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLSRADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEISVEMDAAPGIDLTKILAEMREQYESLAEK-NRRDAE---QWFFSK
----------------TEELN-REVAVNTEQ--LQSGKTEITELRRTIQ---SLEIDLQS
QLSTK---AALEGTLADTEARYGTQLAQLQALITSV-EEQLAELRCDMERQ--NHEYRVL
LDVKCRLEQEIA----TYRRLLEGEDAHISSQYSSAMSS--------------------H
S-----GRDAITTSRQVRTI----VE------------EVQDG--KVVSSREQMA--LT-
--------------------------------TR--------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAMS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISTLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGI-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-SNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RRGSLL-------AGG-G-GFGWGSLCG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSVFGG-------------G-FG-------
-GGVGGSFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTIEEHRDKIMATTIDNS------------RVILEIDNARL-AVDDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFDSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAER-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGIREASS---GGGGS------------
-------------SSNFRINIE----------------ESLDG--KV----------VS-
------S--RTRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISTVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGGGLGAGF
GGGF-G-------A---------GFGGG------------------------------F-
GGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEELRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLEKSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QSSSSFSQGQSS-
------------------------------------------------------------
------------------------------------------------------------
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----------------------------------EMKALQCAAGGNVNVEMNAAPGVDLT
LMLNNMRAEYEALAENNRRDAEA--WFNEKSATLQQQISDDAGAATSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIDTYCRLIDGDGDLCS----KSKSFGSGSSGNSTK-DVTKTTLV
KTVVEEIDQRGKVLSSRIHAIEEKASKVANGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GFG----GGF
GG--------GFGGGLGG-----GFGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPGE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGGGLGAGF
GGGL-G-------G---------GFGGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EDQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QGSSSFSQGQSS-
------SN----------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYHRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-----------------------------MSVRYSSTSKKFTS---SRS----GCGG---
-------------------GGGGSSHRISCSKGS-------------LGGGYS-----S-
-GAFSN-S---SF--SRGSAGGGCFGGSSG-GYGG--------------------GIG--
--------GGLGGG------------------SYCTGYV-------------GGNFGGVY
GGGSYGGGSFGGG-SFGG----------------GGY--------------GGNFG-GGL
G--DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGGS--G
RREP-RDYSKFYQTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVSLRQSVEADINGLRRVLDELTLTKSDLEMQIESFTEELQYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEELAEQ-NRKDAE---AWFIAK
----------------SKELN-TEIDSNIQQ--MSSHKTEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISVL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGGSSGGGHGGSFGGGSS------------------
-------------------------------GGGHSGGGQAGSG-SFKPS-----SNS--
------------------------------------------------------------
-------------------------------------------------------SS-VS
TG----ESSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFSSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------SAYG---------------GLSV-TSSRFSSGGA-CGIG------
--------GGYGGGF----SSSSSSFGG------------------------GAGFGGGF
GG---AGFGSGFG-------------GG------------------------------F-
-G-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQRPAE--
---I-KDYSPYFKTIEELRSKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLAQIQEMISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGED--------FS--SS------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRSKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQVTSS-SFIKG--------SSGLG----
----G-----------------G-----LSR------------------ASCRLS-----
---------------SNLGA----------GSCRL-------GSV-----GGLG------
--------SALG------GSSYSSCHSFGYGG----------------------------
------------------------------------------------------------
----------GEKATMQNLNDRLASYLDKVRAMEEANTELE---VKIRDWYQKQAPRP--
---A-RDYSHYYHTIEDLKSKVLTDTVDNA------------NILLQIDNARL-AADNFC
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIENFKEELAYLWKNYEE----
-EMTALRGQV-GGEINVEMDAVPGVALSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKREIAELRRTVQ---TLEIELQS
QLSMK---ASLEGSLAETENHYCVQLAQIQGLIGSV-EEQLAQLRCQLEQQ--NQEYRIL
LDVKTRPEQAIT----TYRRLLEGEDAHLTQY----------------------------
------KPKEPVTTHQVRTI----HN------------LMSVHFRAILATKSYFK--NE-
--------------------------------IFRTFQI---------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKATKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSFSSKHTTT-TMYTK--GRSSSGSCVTGGSGG
RANSG-------------------------------------------------------
-------------------------------RCSSPA---RCGMS-ARSYCGGMSYGG--
-------------SGI---------------------------DSSFAGGALGCGYGGGY
GSSRF------------G-----HLGGGF------------------------------G
ICNEAPLLSCDEKMTMQNLNDRLASYLDKVRCLEEENGQLE---CKIKEWYDRQGPVN--
E--S-KDYAAYYQQIEDLKNQIVCATVENS------------KLVLDIDNNRM-TADDFR
M-KY-ETELALCQNVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEE----
-ESKHLKKQS-SGDVSVEVNTCPGPDLKKVLDELRCQYENMIEN-NRREVE---KWYESK
----------------MEEVN-LEVCNSSKE--AEDCNNQIVDLKRQLQ---TLEIDLQA
QLSLR---DTLQDSLAETECRYNGHLAEIQNQISCV-EQQLGELRAEMECQ--NREYREL
LDVKCRLEQEIQ----TYRCLLEGGQHDIATGHSSGSS----------------------
---------------------G-------G-G-------------ISRQSSG--STTRS-
--------------SPSRPSHPDSK------GHSR-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRISS---S-------RAGGSS
---------------SVRVSAGGSS---SSSRCGLGGSS----ARGFRGGA-G-----S-
----------------------CGLSGGLSGG-----------------------FGGGF
GSCSVG--GGFGGASG-----SGLGFGGGSG--FGG----------------------GS
G--------FGGGSGFGG---GSGFGGGASGG----FCNYGGG-------LG-----G--
GTGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANADLE---NKIKEWYEKYGPGSGD
GRSG-RDYSKYYPIIEDLRNQIITASVENA------------GMVLQVDNARL-AADDFR
L-KY-ENELHLRQAVEADINGLRKVLDELTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKNMQGSS-GGGVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---NSLEGTLADTEANYMAQLSEIQMRISSL-EEQICQIRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-SFGGS-DFRNSGSRNM--------G-----
------------------------------------------SR-DS------------T
------------------------------------------------------------
---------------------------------------------------SGDSKS-GS
H----SSQGRDP---NK----T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSHVSNI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------------E---G-GGFGAGNACGV-PGIGSSF-SCVLGGSSSAGAY
SGG----------TG----RGSASCAAFSGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIISATTSNANV
VLQNDNARLTA-DDFRLKYENELALHQSVETDVSSLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCASGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQPIFDDAGATSSARNEFTEMKRXXX
XXXXXXXXXXXX----KHSLECSLIETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDDGSCFKS----K--VYGGPGNQIK-DSPKTTMV
KTIVEEIDPRGKVLSSRVHTVEEKITKVNNVKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQSST-----S----------VGGGL--
-G-------------------------GH-------------SS--FRAPSIHG------
---------------G-SG--------------GRGISVSSARFVSSGAGGALG------
------------GG------YGGGMSGGNYG--------------------------AGF
GSGFGGGFGGGFGGGFGG-----GFGG----G-----------------A--------AC
GAGNDGLLSGNEKITMQNLNDRLASYLDKVHALEESNADLE---VKIREWYQKQGPTS--
---PARDYSHYYKTIEDLRDKILDATIDNN------------KIVLQIDNARL-AADDFK
T-KF-ESEQALRMSVEGDINGLRRVLDELTLARSDLELQIETLKEELAYLKKNHEE----
-ELGALSGHL-GGQVSVEVDSAPGIDLTKILAEMRDQYELLADK-NRRDAE---AWFTTK
----------------TEELS-REVAVNTEQ--LQSSKTEITDLRRTLQ---GLEIELQS
QLSMK---AALEGTLADTENRYSAQLCQIQNLISNI-EAQLVEVRSDMERQ--NSDYKML
MDIKSRLEQEIQ----TYRQLLDGHDLHF-SGADSGIIDKSG------------------
---------DGKKH----------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------VRLFPGTMSLSVRAATGPLQFSS---R-S----GYGGG--
---------------SVRLSST-------SSAGS-FGG-------GFGG---G-------
-----------PL--LNF------------------------------------------
----------GGGGYG---GGLGAGYGGGLGAGYGGGL----------------G-----
-------------GGYG--------GGGFSGGSGAG--------------FGGGY--GSG
GGGESSLLSGTEKETMQNLNDRLAAYLDRVHSLEEANTELE---RKIREWYEKNGPGTGA
LGAG-RDYSKYYPVIEDLRNKIINATIENA------------RIVLQIDNARL-AADDFR
L-KF-ENEVALRQSVEADINGLRRVLDELTLTRADLEMQIETLNEELAYLKKNHEE----
-ELIGFQSNA-TGQVSVEMDAAPGVDLTKLLNEMRAQYESIAEQ-HRKEAE---AWFNEK
----------------SGELK-REISTHSEQ--LQYGKSELTDLKRTLQ---SLEIELQS
QLALK---KSLEDTLAETEAGYCTQLAQMQLQIGNV-ESQLFQVRADMERQ--NAEYQNL
MDIKTRLEMEIE----TYRRLLDGEIGKKGF-CSFESASVTSAKS---------------
-------------------------------------------V-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSRDPNK-------T-----------------RKIK-----------------
---------------TIVEEVVDGKVVSSKVKEVEEKI----------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRNISASSARFVSSGSGGGYG------
------------GS------MRVCGFGGGAGSAFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTTEELRDKIMATNIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGSS------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------VD----------------------FPSNSMS---------
-----------------------------LSVSTCGMPRRLSS---Q-S----GTAGK--
---------------ARAMSTS--SV-GSV-----CGGS----TLGFGG---S-----R-
GGAFTA-A---SM--FGFS---SGFGGGSA------------------------------
------------GTIA---GGLVAGYGLCLG-----------------------------
----------------------------------TSL---VGSPR----G--GSL--GIL
SVNDGGLLSGSEKETMQNLNDRLASYLDNVRALEEANRELE---TKIQEWYETRGAGAGD
PGSQ-SDYTKYYALVEDLRNKIISASVGNA------------RLILQIDNARL-AAEDFR
M-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQVEGLQEELAYLRKNHEE----
-ELQSLREGS-PGQVSVEMDATPGVDLTTLLKDMRAQYETVAEQ-SRKDAE---AWFIEK
----------------SGELR-KEISTHQGQ--LQSSKGEVTELRRSLQ---NLEMELQA
QLAMK---KSLQDSLAETEGDYCGQLSQVQQLLGCL-EAQLLQLRGDTERQ--DSELQRL
LNVKARLELEIE----TYRRLLDGEPEGAGLGDTA---SEADSKSQ--------------
----------------------------------------APST-G--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDSTK-------S-----------------RKIK-----------------
---------------TIVQEVVNGQVVSSQVQEIEELM----------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SFRFS
GGS-RICSRA----GSVRLSRA---G-AGFVAGNVCIG-PGAESSF-SCTLGGVSA----
----GGSFS-NGGEG----LGGGNGTGFPGSEPGLLSGNEKVTMQNLNDRLALYLEHVAA
LEEANTDLERKIKGWYEKYGP-GCGRGLDQD---YS-RYFSVIEDLKRQIISVTACNASI
ILQNDNARLTA-DDFRMKYENELALHQTVEADTNGLRKVLEGLTHSATDLDLQFEALSEE
LTYLQK--NHEE----------------------EMEVLQNASGGNINVEMNAAPGVDLT
AVLNNMRAEYEDLAEQNRKDAEA--CFKEKSASLQQQISDDAGAATAARNELTELKRNLQ
TLEIELQSLMAM----KQSYESSLAETEGNYYAQLQQIQDQIGAKEEQLQQIRTETEGQK
LEHEQLLGIKTCLEQEIETYCTLLDGEQRRSKPTCYKLKDSKPVN---EVK-DSTEETFV
RTMVEELDQLGNLLSLRVHSVEEKSSKISNITM--EQRVTAKAL------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLCG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSVFGG-------------G-FG-------
-GGVGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIHDWYQKQTPTS--
---PECDYSQYFKTIEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQGIEADVNGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGIREASS---GGGGS------------
-------------SSNFHINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MTTYSVQNSF-SSGAG----------GFGAA--
GS--------------------GGS-RLSSVR-------VGG---SYRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSVG-GGY-------
------------------------------------------------------------
---------------------------------------------------GGGFDASCA
FGGGDGLLSGNEKITMQNLNDRLATYLQKVRALEDANAELE---VKIRDWYQKEAPTS--
---PARDYSNYYKIIEDLRDKILAATIDNS------------RVVLEIDNARL-AADDFR
L-KY-ENELFLRQSVESDINGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEE----
-EMKEYSNQL-SGTVNVEMDAAPGIDLTRILSEMREQYEALAEK-NRKDAE---AWFLTQ
----------------TDELN-REVATHTEQ--IQSSKSEITELRRTVQ---SLEIELQS
QMSMK---AGLEANLRDTEGRYCAQLAQIQNLITSV-EEQLSEIRCDMERQ--NQEYRML
MDIKSRLEQEIA----TYRQLLETQDSQM-SGVNPKDATTAGRVRGGTED----------
-------EGRSSSTRDRRY-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------------------------------MS---------
-----------------------------LSVRTSALSRRSSS---Q-S----GVAAR--
---------------PWGASAS--SV-AGS-----YGGM----ASGLGV---G-----C-
GGLLSA-A---SM--FGCG---SGFSGGST------------------------------
-------------CSL---PGLGTAYGGPLGGGFGGL-----------------------
-------------------------------G----I---GGNSG----G--GSL--CVF
SDNDGGLLSGSEKETMKNLNDRLASYLGKVRALEEANAELE---NKIREWYETRRT--GD
SGPQ-SDYSKYYPLIEELKNKIISASVGNA------------QVILQIDNARL-AAEDFR
V-KY-ENELALRQTVEADINGLRRVLDELTLARADLEAQTENLTEELAYMKKNHEE----
-ELQSFQAGA-PGDINVEMDAAPGVDLTKVLNEMRAQYEAMADQ-NRKDAE---AWFLEK
----------------SGELR-KEISSNTEQ--LQSSKSEITDLRRMMQ---NLEIELQS
QLAMK---KSLENSLAETEGGYCCQLSQVQQLIGNL-EEQLQQLRADAERQ--NADHQRL
LGVKARLEMEIE----TYRQLLDGEAQGDGFDESL---LLT--ASK--------S-----
---------------------------------------QTPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVQELEEAI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------------------------------M-----SLRLP
SGSRRACARPTT--GSLRLSGG---G-ASFGAGNACSL-PGIGSGF-SCAFGGS-ALGGN
A------------------GGSNSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKSQIIASTTSNSNA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCVAGGNVNVEMNAAPGVDLT
VLLNNMRSEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KQSLECSLTETESNYCVQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVLLEKEIETYCLLIGGDDGACKSGGYKTKDYGSGNMGSQVK-DPAKAIVV
KKVLEEVDQRSKILSTRLHSLEEKSQNLNNVPN--IRKIKAKVLV-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQTSS-------STYGS-GFGGGSCQL------
-----------------GG--------------GRGMSSCSSRFVSSGSVGGYG------
------------GG------I-SCGFGAGAGSGFGGGFGG------GAGG----------
------GYGGVFGGSFGG-----GF---------------------------------DL
VGGDGGLLTGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWHLKQSPTS--
---PERDYSPYYKTIEDLQEKIRAATIENS------------GIILEIDNARL-AADDFR
L-KY-ENELSLRQSVEADINGLRRVLDELTLSRADLEMQIESLNEELAFLKKNHEE----
-EMKEYSNQV-VGQVNVEMDATPGIDLTRTLAEMREQYEALAEK-NRRDAE---AWFQKK
----------------SEELN-KEVTSSTEM--IQTSKSEITELRRTLQ---GLEIELQS
QISMK---AGLETTVAETECRYAMQLQQIQGLISSI-EAQLGDLRSE-------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRLS
SGSRRAGPRA--TAGSLRLSSG---G-AGFGAGNACGV-PGIGSGF-SCAFGGSS-SGGN
A------------------VGGNPCAGFTVSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANTDLEQKIKGWYEKYGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAQYEGLAEQNRRDAEA--WFNEKSAPLQQQISEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYGPGNVGNQIK-DPVKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQYSS---SRS----GGGG---
--------------------GGGSSLRISSSKGS-------------LGGGYS-----S-
-GGFSG-G---SF--SRGSSAGGCFGGSSS-IYGGG-------------------LGSGF
GG-------GY-------------------GSSFGGSYG--------------GSFGGGY
GGGGFGGGSFGGG---------------SFG---------------------GGLG-GGF
G--DGGLISGNEKITMQNLNDRLASYLDKVRALEESNYELE---VKIKEWYEKYGNS--R
QREP-RDYSKYYQTIDDLKNQIFNLTTDNA------------NILIQVDNARL-AADDFR
L-KY-ENEVTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEK-NRRDAE---AWFNEK
----------------SKELT-TEINSNLEQ--VSSHKSEITELRRTIQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGSYGGGR----G------------------
----------------YGGSSGGGG-----------------------------------
---------------------------GGYGGGSSSGGYGGGSSSG--------------
---GGHGGSSGGSYGG-GSSSGG----------GHG--------GGSSSGGHKSTTT-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------GGSSG-GYGG---------------------G---
----SG--GGFGGGSF---GG---GYGSS---SLGGGFG-------------GGSFG---
-GGSFGGGSFGGG-SFGG----GSFVG-------GGF--------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNA--G
QREP-RDYSKYYQIIEDLKNQIINLTNDNA------------NVVLQIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRNQYEQLAEQ-NRKDAE---AWFNEK
----------------SQELT-TEINSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEG----------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSLR-------LGAGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SGGG--------
------------------------------------------------------------
-----------FGSSLAG-----GL-----------------------------------
-TRSDGLLGGNEKLTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRP-A--
---ETKDYSHYFKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISALRGQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSKSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISSM-EAQLSDVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRSLLEDQDAHY-NNLPTPKA---L------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSFSFRS---QSSAAS----------SFGAL--
-G-------------------------GGSVR-------VGAGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-ATGG--------
------------------------------------------------------------
-----------FGGGFAG-----RMG----------------------------------
--GTDALLGGDEKVTMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQKQGP-G--
---PARDYSHYFKTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETELNLHMSVEADINGLRRVLDDLTMTRSDLEMQIEGLKEELAYLKRNHEE----
-EISALRSQV-VGQVSVEVDSAPGTDLTKILSEMRSQYEVMAEK-NRKDAE---AWFISQ
----------------TEVLN-KEVATNTEM--IQSSKTEITELRRTMQ---GLEIELQT
HLSMK---ATLEGTLAETEERYRVQLAQIQALIGSL-EAQLSNLRADTERQ--NLEYQQL
MGLKSRLEQEIA----TYRSLLEGQDAHY-NSLPGPKG---L------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-S-SRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGGGLGAGF
SGGL-G-------A---------GFGGG------------------------------F-
AGS-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQQ-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QSSSSFSQGQSS-
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYG---------------GLSV-TSSRFSSGGA-CGMG------
--------GGYGGGF----SSS-SSFGGALGGGYGA--------------GFGGGF----
--------------GFGS-----GLGGG------------------------------L-
GG-GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANTDLE---VKIRDWYQKQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNSMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKIAEK-NRKDAE---DWFFSK
----------------TEELN-REVTTNSEL--LQSGKSEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQMQEMIGSV-EEQLAQLRCEMEQQ--SQEYKML
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------AQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VV------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTSIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-TLGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEADTELE---VKIRDWYQRQAPGP--
---A-RDYSQYYRIIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

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--------GGGFGSGFAG----------------------------------------SF
GMGGDALLSGNEKVTMQNLNDRLAAYLDKVRRLEEENAQLE---HHIREWYRKQAPTA--
----SKDYSAYYQTIEQLQNQILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELFLRQSVESDINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMKEYSTQL-SGTVNVEMDAAPGIDLTRILTEMREQYEALAEK-NRKDAE---AWFLTQ
----------------TDELN-REVATHTEQ--IQTSKTEITELRRTLQ---SLEIELQS
QMSMK---AGLEANLRDTEGRYCAQLSQIQNLITSV-EEQLGEIRCDMERQ--NQEYKML
MDIKSRLEQEIA----TYRQLLETQDSQ--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------TSYCYSQ----SSAKS----------SFGGL--
-G-------------------------CGSVS-------LGPGV-------AFC------
------------------A--------------PS----------MHWGRRPRR------
------------FR----------------------------------------------
-----------VLRP--G-----V------------------------------------
LAASDRLLEGNEKLTMQNLNDRLASYLDKVRALEAANCELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLQDKLLGATIENS------------RIVLEIDNAHL-AADNFR
T-KT-DTEQALRMTLEADINGLHRVLDELTLASTDLEMQIEGLKEELAYLKKNHEE----
-EISGLRGQV-GGQVSVEVDSARGTDLARILSGMRSQYKVMAEQ-NWKDAE---AWFTSR
----------------TEELN-REVAGHTDQ--LQMSLSKVTDLQRTLQ---GLE--LQS
QLSMK---ATLEGTLAETEARVGAQLAQIQSLINGI-EAQLGDVRADSERQ--NQEYQQF
TDNKSRLQQEIA----TYRSLLEGREDHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MSTCSHQFTSS-RSMKG--------SCSIGGSI-
---GG-----------------GSS-RISSV-----------------------------
---------------------------------------LAGGSCHAPT-CGLG------
--------GGYGGGF------GSSS-------------------------SFASGFGGGY
GGGLGA--------------------SV---------------------------V--AW
------VVALLVKVTMQHLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQWPSE--
---I-KDYSPYFKTIEDLRHKIIAATIENA------------QPILQIDNARL-AADDFR
T-NY-EHELALRQTVEAGVNGLCRVLDELNLARTDLEMQMEGLKEELACLRKNHEEMRLL
LEMLALRGQT-GGKVNVETDAAPGVDLSCILNEMCNQYEQMANL-TF---H---SAFLSQ
----------------TKELN-KKVASSSEL--VQSSRSEVTELQRVFQ---GLEMELQF
QLSVK---ASLENSLEETKGCYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDMKTRLKQEIA----TYRRLLEGEDLSDSF----SPP--LLSP--TV--F---------
------TSS---SSCQTWPI----LK------------E--QG--SSSFSQGQCS-----
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
GGSRHLCLPS----GSVRPPSG---G-AGFAGSSAGGN-SVAGSGF-SWALGGALV----
----SAPGGGHADGT----LGNAAGVGFAGSEGSLLSGNEKVTMQNLNNRLASYLDNVKA
LEEANAELERKIKSWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKSKIISSTAANANV
ILQIDNARLAA-DDFRLE------------------------------------------
-----------------------------------MKVLQCSAGGNVNVEMNAAPGVDLT
VLLNNMRGEYEALAEQNRRDAEA--WFQEKSATLQQQISNDVGAATSARTELTELKRTMQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQIDALEEQLHQVRTETEGQK
LEHEQLLDIKAHLEKEIETYCRLIDGDGN----SCSK-----SGSSGTPSK-DVSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKITNSKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGM--
-G-------------------------GGSVR-------FGSGG-VFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRIVTS-SSGN--------
------------------------------------------------------------
-----------YGGGYGG-----SFGG----T--------------------------L-
-AVSDGLLAGNEKVTMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYFKTIQDLRDKILGATIDNS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSAPGVDLAKILSDMRSQYEVMAEK-NRKDAE---ALFITR
----------------TEELT-KEVAVHTEQ--LQASKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYGAQLAQIQGVISSI-EAQLSDVRADTERQ--NLEYQQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKA---I------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VI-GR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGI---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSSFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTAD
A-SQ-SDYSKYYPLIEDLRNKIISASIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHED----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAFQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MSCS-------SRVSS---R-------TRGSSA
---------------VRVSAAGGASF-SGGSSCGLGRGS----ARGFRGGA-G-----S-
----------------------CGLSGGSSWGYGGS-------------------FGGGV
SSCSVG--GGFGGASG-----SGAGFGWGSG--LGG------------------------
---------------------GSGLGGGASRG----FYSYGGG-------LG-----G--
GIGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANADLE---NKIKEWYDKFGPGSRD
GGSG-RDYSKYYPIIEDLRNQIITAMTENA------------GIVLQIDNARL-AADDFR
L-KY-ENELHLRQTVEVDTNGLRKVLDDLTTTRSGLEMQIESLTEELAYLKKNHEE----
-EMKRVQGGS-RGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYMAQLSQIQIQISSL-EEQICQIRGETECQ--NTEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGSS-DFGGS-DFRSLGSRNT--------G-----
------------S-RNM----G--------------------SR-DS------------S
M-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SVQGRDP---SK----S-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQVSNV----SEVKI---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGGGLGAGL
GAGL-G-------G---------GLGGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QGSSSFSQSQSS-
------SN----------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQSSA-------ASYGG-GFGTGSCQL------
-----------------GG--------------GRGFSTCSTRFASGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGY----------------------
--------GGSFGGSYGG-----SFS--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQKQSPAS--
---PERDYSRYFTTIDELRAKILAATTDNN------------RIVLEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAFLKKNHEE----
-EMKEFGKQV-VGQVNVEMDAAPGIDLTRVLAEMREQYEAMAEK-NRRDAE---AWFQSK
----------------SAELN-KEVASNTEM--IQTSKTEITELRRTLQ---SLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISGI-EAQLSELRSEMECQ--SQEYQML
LDIKTRLEQEIA----TYRSLLEGQDSRL-TISASPTGSASGSASTSP------------
-------------------------------------------------------RRVS-
-------DIRRF------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRSVSSCSTRFVSGGSAGGYG------
------------GG------V-TCGFGGGAGSGFGGGYGG--------------------
------GLGGGFGGGYAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYHKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMRAQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEDQDAKM-TGIPSSAGSVSPRSTSVTTA----------
-------S------SVS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-TS-S---S----------TFGGC--
ST------------------------RGGSLR-------VGG-G-GFGGGSLYG------
---------------G-GG--------------SRGISASSARFVSSGMGGGYG------
------------GG------M-SCGFGGGAGSSFGG-------------G-FG-------
-GGFGGGFGGGSGGGFGG-----GFG--------------------------------GD
FGGGDGLLSGNEKITMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQSPAS--
---PERDYSRYFKEIEELRDKILAGTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAFLRKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAVAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IHSSKTEVTELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGLIGGV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRSLLEGQDARW-PRGQTPLLFLAVLGGAAGG-----------
-----------GSSNNFRIKVE----------------ETVDG--KV----------VS-
------S--HKRD---------------V-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MATTTSIRQFSSS-GSIKG--------LCAPG----
----G-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGV----------GSCGNMSV-ASSRFS-----AGLG------
--------GGYG-------G----GYTCNLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGGEKETMQNLNDRLATYLDKVRALEEANTDLE---VKIREWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SFVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEE----
-EMNALRSQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------TSQ
P-----SRDAMVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGAATSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GMGG-----------------GSS-RISSVL---------------A------P-----
---------------SAYG---------------GLSV-TSSRFSSGGA-CGLG------
--------GGYGGGF----SSSSS---------FGG--------------GYGGGLGAGL
GS---------------G-----GFGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---T-RDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMLALRGQS-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRRDAE---EWFFSK
----------------TEELN-REVATNTEA--LQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------AQ--FSSGSQSSR-
--------DVTSSSRQVRT-K---VL------------DVHDG--KVV------S-----
---------SHEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLGSCGG--TGSGRFSSG---G-VGFGAGNACGV-PGIGSGF-SCAFGGTSSPGGY
GAG----------LG----GAIASCAAYTGNESGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPVIEDLRNQIITVTTGNANV
VLQNDNARLTA-DD-RLKYENELALHQSVEADMNGLRRVLDELTLCRTDLEIQLETLTEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCVKS----K--SYRGPESQIK-DPSKIAMV
TTVIEEIDPRGKVISSRVHTVEEKSTKVNNSKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQFSS---SRS----GGGG---
-------------------GGGGSSLRISSSKSS-------------HGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG-------------------------
----------FGGGSF---GG---GYGGS---NFVGSCG-------------GGGYG---
-GGSFGGGSFGGG-SFGG----GSFGG-------GGF--------------GGGFG-GGY
GGDGGGLLSGNEKVTMQNLNDRLASYMDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYQTIEDLKNQILTLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLSKADLEMQIESVTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQMLDNMRNQYEQLAEK-NRKDVE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLEGEGGSGGGSYGGGRGGG--------GGGSHGG-----
---------------SYGGG--SS---GGGSHGGSYGGGSSG-G-G--------------
-----------------GGGSYGGGSSGGGHGGSSGGGYGGGSSSG--------------
---GGHGGSSGGGYGG-GSSS----------------------GGQSGSGGFKSSSS-GS
GGD---QSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SGSRHICLRSG--TRSTRPPNG---G-IGFVGSNAYSS-SGAGSGF-SCALGGGLG----
----SVSAGNYAGGA----LGSAACAGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEDANADLERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLNCKIISSTTANANV
ILQIDNARLAA-DDFRLKYENELALHQNTEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
LLLNNMRAEYEGLAEQNRRDAEA--WFNEKSATLQQQISDDAGAATSAKSELTEMKRTLQ
TLDIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKAHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-ELSRTTLV
KTVVEEIDQRGKVLSSRVQSIEEKTSKMTNGKI--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
C-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSACSTRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSSFGGGFGG--------------------
----------GFGGSFGG-----GFC--------------------------------DF
GSSDGGLLTGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWHLKQAPTS--
---PEHDYSHYYKTMDELRDKILAATIENN------------RVVLEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---DWFHHK
----------------SAELN-KEVTSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYRML
LDIKTRLEQEIA----TYRSLLEGQDAKL-TGSASAGVNVSSSG----------------
---------------SS-STTA----------------SN-------T-----AGRRTS-
-------D-VRRS-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSL--KQYSS---SRS----GGGGG-G
-------------------GGGASAHRISSSKGS-------------LGGGF--------
----SS-R---SF--SRGSSSGGCIGGSSG-GYGG--------------------LGGGF
GGR-----GSYG------------------GGSFGGGYG-------------GGSCGG--
-GGGFGGGSFGGG-SYGG----GSFGGGSFGG--GGY--------------GGGFG-GGY
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEQLNYELE---SKISEWYKKHSNI--G
GGEP-RDYSTYYNVIDDLKNKILKQTTDNA------------NTLLQIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKSDLEMQIESLTEELQYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDTNIEQ--TSSYKSEITELRRNVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCMQLSQIQTQISAL-EEQLQQIRAETECQ--NSEYQEL
LDIKIRLENEIQ----TYRSLLEGEGSGRGGGRGGGSSGG--------------------
-----------------------G---HGGSSGGGYGGSSGG-G--YG------------
----------------GSSGGGHGGSSGGGHGGSSGGGYGGGQ-----------------
--GGSSGGSHGGSYGG-GSSG---------------------GGGQSGSGGFKGSSS-GS
PGE---S-SKGPRSGDTSGVTR-----------------GSLR-----------------
---------F----LSPVLAF---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-T--S---S----------SFGGG--
ST------------------------RGASLR-------AGG-G-SFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGYG------
------------GA------M-SCGFGGG----------------------AG-------
-SGFGGA----FSGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PERDYSHYFKTIEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTHVLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGLISSL-EAQLSELRCEMEAQ--NQEYNML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGVREASL---GGGGGGG----------
-------SS--SSSSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSQRYNS-SKQYSS---SHS----GGGG---
---------------------GGSSIRVSSSRGSVYGT-------GSIGGGFS-----S-
GGGSS-------------------YVSCSKGGFGSA-------------------SIRSF
GRGIGG--GSYVGSSF---G----------------------------------------
-GYGFGGG------SYSE----GNYGGGSFG----------------------GVLGGGF
GGGDGGLLTGNEKVTMQNLNDRLASYLDKVRSLEESNSELE---QKIKEWYEKNGNA--N
QREP-RDYSHYYDQIKELKDQILNLSTDNA------------NVLLQIDNARL-AAEDFR
L-KY-ENEVTLHQSVEADINGLRRVLDDLSLAKTDLEMQLENLNEELDFLKKNHEE----
-EMKDLQNVS-TGDVNVEINAAPGVDLTEYLNRMRSEYETMAEQ-NRKEAE---AWFNEK
----------------SKELT-TEIDTNVEQ--VSSYKSEITELKRNVQ---ALEIELQS
QMALK---QSLEATLGETEGRYCVQLSQIQAQITAL-EEQLQQIRAETESQ--NLEYQVL
LDIKIRLENEIQ----TYRSLLEEGGLSLSFSLPLSLFPPLSLSPS--SLFSLFL-----
------------SCGKLKGGRGCDI--SKTTLVKTVVEELDQRG-KVLSTLVHSIEEKSS
K-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SASRRLASCGG--AGSVRLSSG---G-AGFGAGNACGV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----AGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIISATASNASV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCVKS----K--GYRGPGNQIK-DSSKAAIV
KTVVEEIDPRGKVLSSRVHTVEEKATKI-NTKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQSSS-------ASYGG-GFGAGSCQL------
-----------------GG--------------GRSISTCSTRFVSGGSAGGFG------
------------GG------V-SCGFGGGAGSGYGGGFGG------------------SY
GGGFGGGFGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQTPTS--
---PERDYSPYFKTIDELREKILAATIDNN------------RIILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQL-AGQVNVEMDAAPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHSK
----------------SAELN-KEVSSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKL-IGFTTGGKKITQWERRSGSY----------
-------S------SAWGGGTS----------------GS-------S-----SGRRVP-
-------E-NSRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
--------------------------MTTCSRQFTSS-SMK----------------GT-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-SSSRFSSGGA-CGIG------
--------GGYGGGF----SS-SSSFGGALGSAYGG--------------GYGAGLGAGF
GA----GFG--------G-----GMGGG------------------------------F-
GV-SDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEELRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRVLNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--LQSGKSEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------EGL-------------------------------------------------
------------------------------------------------------------
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---------------------------MSYSTKTTLT-SSST----VGGGGTRVS--GGG
GSGGSRTGT--------------ST-VKSSVGNFSCKS--YGGG-----SKC--------
-----------SYGGGGGGGY--GGRLVSCGGYGAGFGSTCGGFS-GGGYGGGGVCGSGF
GG-----------SVMGAGGVCGGGFGGGA---MGSGFGG---S----------------
----CGFGGSG-GFGGSG-----GFG---------------------------GSG--GF
-CVDDGLLNTNEKVTMQNLNDRLANYLEKVHGLETSNADLE---KLIKEWYQNQGPTA--
S--L-KDYTPFLKEIDDIDKEIVAASVECN------------KVAVDVDNTKM-TIDDFR
T-KA-EHEMALRQNVEADINGLRPMLDQLTISKSDLEAEYESLKEELISLIKNHEE----
-EIKGLIQQT-VGDVNVEVNAAPGCDLTQTLDDLRREYDAIIQR-NRKEVE---QWYACK
----------------IAEVN-QEVNTSGQD--IETNSKQITELRRECQ---NVEIELQS
QLSML---KSLQSSLEDTECRYNIQLQQMQSVISSV-EEELAHIRCEIENQ--SQEYKML
LGIKMQLEKEIA----QYRSLLDAGSKDLPGGPE--------------------------
----------------------------GG-V--ASGGVFRG------EGGR---GGG--
--------------------V-STV---PRGGGS---G--GGSVV---------------
-----------------------------------------------------------R
-GE---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------G----------------
-----------------ST---------------------------------G--S-RGE
DRRP-S------------------------------------------------------
---------------------------K--------------------------------
------T--GEN--------------------FVYTRRTFE-------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------S-FKGLGGGSVRFG--
---------------------------------PGVAFRA---QYA--QGLRSCGV----
----SVSS------------------SRFVSS-----------------PSSGGYG--GV
LAAAEGLLAGNEKL---------------VRALEAAKGELA---VKIRDWYQKQETGS--
---S-HDYSRYYKTIQDLRDKILGATIENS------------RIVLQIHNARL-AADDFR
T-KF-ETEQALRMSVEANIKALRRGLEELILARSDLEMQIETLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGADLVKILSDMQSQCEVLAEQ-NRKDAE---ACFTSR
----------------TEEPN-REVAGHTEQ--LQMSKTER-------L-----EIELQS
LLSMK---ARLEGTLAETEAHFGVQLAEISD---------IEALLGDIERQ--NQEYQRL
LVVKLRLEQEIA----TYRSLLEGKEDRYNNLSASKVL----------------R-GGRR
PGASAVLQ-------------RVSPGWA-------------DG--KEGTLSLRYP-----
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
--------------------------------DL----GMGGS----------EFGARGR
LL-------------------------RAQHA-------LGPAA-------AAR------
---------------P-CP--------------PPASCLSSSS-----------------
------------------------------------------------------------
------------LGGYSG-----V------------------------------------
LAASDRLLEGNEKLTMQNLNDRLASYLDKVRALEAANCELE---VKIRDWYQKRGP-G--
---PSRDYSHYYKTIQDLQDKLLGATIENS------------RIVLEIDNASL-ATDNFR
T-KT-DTEQSLRMTVEADINGLRRVLGELTLASTVLEMQIEGLKEELAYLKKNHEE----
-EISGLRGQV-GGQVSVEVDSARGTDLARILSDMRSQYKAMAEQ-NWKDAE---AWFTSR
----------------TEELN-REVAGHTDQ--LQMNLSKVTDLRRTLQ---GLE--LQS
QLSMK---ATLEGTLAETEARVGAQLAQIQSLINGI-EAQLGDVRADSERQ--NQEYQQF
TDNKSRLQQEIA----TYRSLLEGQEYHY-NNLSASKVL---------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
GGSRRSCLQSG--AGSARPPSR---G---VAGGSAGGS-SVAGGGF-SCALGI-------
-----PNVGSHAGGA----LGNT-----AGNERGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKSWYEQYGP-GSCRGLDHD---YS-RYHRTIEDLKNKV----------
-----------------------------EADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLGNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQIFDDAGAATSARTELTEMKRTLQ
TLEIELQSLLAT----KRSLECSLTE----------------------------------
------------------------------------------------------------
--------------------------------------------------

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-------------------------------------------------M-----SLRYS
AGSRLLGFHSG--AGPGRP------S-VGFARSSACGN-SVVGSGF-PCALGGGLG----
----GAPGGSHSTGT----TG-NACVGFAVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKYGP-GSCRGLDHD---YN-NYHLTIEDLKAKIISSTAGNANV
ILQIDNTRLAA-ADFRLKYKNELTLHQNVEADISELRRVLDELTLCRMDRELQYESLSEE
VTYLRK--NHEE----------------------EMKALQCAAGANVNVEVNAAPGVDLT
VLLNNMRAEYEALAEQNRGDAEA--WFGEKSASLQQQMSQDAGEATRARTELSELKRRLQ
TREIELRSLLAT----KHSLECSLSETQGNYCSQLAQIQARISALEEQLHQVRTETEGQK
REYEQLLDVKVHLEKEIETYCRLIAGDEE----SCSKSKSFGSGGSGNSSK-DLSKTTLV
KTVVEELDHRGKVLSSRIHSIEEKTSKLTNKA---EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYG---------------GLTV-SSSRFSSGGA-CGMG------
--------SSYGGGF----SSSSS-FGEGLGSGFGR--------------GFGGGFGGGF
GGALGGGFGGGFGGGIGG-----GIGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---I-KDYSPFFKTIEDLRSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLSQIQEMISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSSSTQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVSS--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MATTLLQTS---S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRTISASSARFVSSGSAGGYG------
-------------------------------GGFGG-------------G-AG-------
-SGYGGGFGGGFGGGFGS-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWYQRQSPTS--
---PERDYSPYFKTTEELRDKILAAAIDNS------------RVILEIDNARL-AADDFR
L-KY-ENEMALRQSVEADISGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQL-AGQVNVEMDAAPGVDLTRVLSEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKSEITDLRRTIQ---GLEIELQS
QLSMK---AGLESTLAETECRYAAQLQQIQGLISSI-EAQLSELRSEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDARM-AGIGTGEASL---GGGGG------------
--------------GKVRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SFRLS
GGSRQICSRA----ASVRLSGG---GTTGFVAGNVCVG-SGAGSSF-SCTLGGISS----
----GGSFC-NGGGG----SGSGVGAGFLGNEHGLLSGNEKVTMQNLNDRLASYLDHVRA
LEEANADLEQKIKGWYEKCGP-GSFRRHDHD---NS-RYSSVIEDLKRQIVSVTSCNASI
VLQNDNARLAA-DDFKLKYENELALHQSVQADTSNLRRALDELTLCITDLEIQCETLSDE
LTYLKN--NHQE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
ILLNSMRAEYEDLAEQNRKDAEA--WFNEKSATLQQQIFDDAGAATAARNELTELKRNLQ
TLEIELQSLMAM----KHSYECSLAEMEGNYCDQLQQIQDQIGAMEEQLQQIRTETEGQK
LEYEQLLDIKIFLEKEIEIYCNLIDGEERKCKSTCYESKGCKPENSGNQVK-DSTEETVV
KTVVEELDQVGNVLSLRVHSVEEKSSKISNITV--EQRVPSKDHNEKKLL

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-------------------------------------------------M-----SLCLS
SGTRRSCSRPTT--GSVRLSSG---G-SGFGTGSTCGV-TGIGSGF-SCAFGSSSTV---
G------------------NGSTSCTSFLGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELEEKIKGWYEKFGP-GSCRGLDHD---YS-RYLPIIEDLKNQIIVSTTSNASA
VLQIDNARLTA-DDFRLKFESELAFHQNVEADVNGLRRVLDELTLCRTDLEIQYETLNEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
LLLNNMRAEYEDLAEQNRKDAEA--WFNEKSASLQQQISDDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCVQLSQIQAQIGALEEQLQQVRTETEGQK
LEYEQLLHIKVYLEKEIETYCLLIDGDEGACKSGSYKSKDLGSGNLGSQAK-ELGKAIVV
KKVLEEIDQRSKVLTTRLQSLEEKAPNN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------YSSGAV-CGLG------
--------GGYGGGL----SS---SLGGALCGSLVG--------------RYGGGLGV--
---------------------------G------------------------------Y-
SGGDGSLLPGNEKITMQSLNDRLASYLDKVHALEEANRELE---TKIHDWYQSQGPRP--
---A-RDYSPYFKTIEDLRNKIIEATIENA------------Q----IDNARL-AVDDFR
T-KY-EHELTLSQSVEADINGLLGVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMLALRNQT-GGDVNVEMDTAPSVDLSRILNEMCDQYEQIADR-NPRDAE---AWFLSK
----------------SEELN-KEAAFNSEL--MQNSRSELNELWRVLQ---GLEVELQS
QLCMK---AFLEKSLEETKNHYCLQLAQIQEQICSL-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLL--------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------MATTSIRQFSTS-GSIQG--------LCAPG----
----G-----------------GFS-RVPSVR--------------VGGA-RMAP-----
---------------SLLGA----------GGGGSMLV-TSSRFS-----AGLG------
--------GGYA---------------FSLGGGY--------------------------
-------------------------GSG------------------------------FG
--VSDALLGGGEKETMQNLSDRLASYLDKVHALEEANGDLE---LKIRDWYQKQGLGP--
---A-RDYSPYFKTIEDPRSKILAATMDNA------------GFVLQIDNARL-AADDFR
T-KY-EHEQSLRLSVEADTNGLRRVLDELTLARADLEMQIESLQEELAFLRKNHEE----
-EMNALRGQA-GGDVSVEMDA-AGVDLSRILNEMRDQYEKMAEQ-NRKDAE---EWFFSK
----------------TEELN-REVAANTEA--LQSSRTEITGLRRSVQ---NLEIELQS
QLSVK---ASLENSLAETEARYGAQLAQLQGLISSV-EAQLAQVRCDMERQ--NQEYQVL
LDVKTQLEQEIA----TYRRLLEGEDAHLASQYSS-SM-------------------ALQ
S-----SREASVTSRQVRTI----ME------------EVRDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNVACVGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGATTSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----NPKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGAGNTCTV-PAIGSGF-SCAFGGSSSVGGY
GGG----------LG----AGGVSCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANANLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIVALEEQLHQVRTETEGQK
LEYEQLLDVKIYLEKEIETYCLLIDGEDGSCSKS----K--GYRGQGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKSTKV-N-KN--EQRVPS---------

------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
GGSRHLGLHPG--AGSVRPPSG---G-IGFVR-STCGN-SVIGSGF-SCALGGGAG----
----GVPGGIHGGGA----PGN-ACAGFAVSEGGLLSGNEKVTMQNLNDRLASYLDNVHA
LEAANADLERKIKSWYEKYGP-GSCRGLDHD---YS-SYHLTIEDLKAKIISSTAANANV
ILQIDNARLAA-DDFRLKYENELALHQNVEADINGLRRVLDELTLCRTDQELQFESLSEE
ATYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFSEKSASLQLQISQDAGEATRARTELTELKRTLQ
TQEIELRSLLAT----KHSLECSLSETESNYCSQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDEASCS----RSKGFESGSLGNSSK-DLSKTTLV
KTVIEELDQRGKVLSSRIHSIEEKTLKPTTSKT--DPRASF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MG--
-T-------------------------NNPIR-------FGSGV-ALRAPSIHG------
---------------G-SG--------------GRGVSVS--RFVSSGLSGS--------
------------------------------------------------------------
-----------YGGGSSS-----SCSS----F-----------------S--------LG
YGGADGLLAGNEKFTMQNLNDRLASYLDKVRALEEANSDLE---VKIRDWYQKQGP-G--
---PSRDYSAYLKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EMNALRGQV-GGQVSVEVDSAPGIDLAKILADMRNQYEVMVEK-NRTDAE---AWFNHK
----------------IEGLN-QEVAVHTEQ--LQTSMTEVTDLRRTLQ---GLEIELQS
QLSMK---AALENTLAETEARFGAQLSQKQFVISNI-EAQLSDIRADTERQ--NQEYLHL
MDVKSRLEREIA----TYRSLLEGQDTQV-NNVPQSPK---AP-----------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGAGLGGGL
GGGL-G-------G---------GFGGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQS-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRTEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QGSSSFSQGQSS-
------SN----------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLGSCGG--AGSVRLSSG---G-AGFGVGSTGSV-PGFGSGF-TCAFGGSSSAGSY
SGG----------LG----GGSASCTAFTGNEHGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFTVIDDLRNQIISATTSNANI
VLQNDNARLTA-DDFRLKFENEQALHQSVDADVSSLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCTKS----K--GYGGPGNQIK-DPSKATVV
KTIVEEIDPRGKVLSSRVHTVEEKSTKVNNMKS--EQRVPS---------

------------------------------------------------------------
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------------------------------------------------------------
------------------MDAAPGVDLTKVLNEMRAQYEAMADQ-NRKDAE---AWFLEK
----------------SGELR-KEISSNTEQ--LQSSKSEITDLRRMMQ---NLEIELQS
QLAMK---KSLENSLAETEGGYCCQLSQVQQLIGNL-EEQLQQLRADAERQ--NADHQRL
LGVKARLEMEIE----TYRQLLDGEAQG--------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MATTFLQ-T--S---S----------TFGGS--
ST------------------------RGGSLR-------AGG---GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGFG------
------------GG------M-SCGFGGG----------------------FG-------
---------GGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PDRDYSHYFKTMEEIRDKILAATIDNS------------RVVLEIDNARL-AADDFR
L-KF-ENEMTLRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGVITGL-ETQLSELRCEMESQ--NQEYNML
LDIKTRLEQEIA----TYRNLLEGQDAKM-AGIGVREASL---GGSSGGV----------
-------GGSSSSSSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
----------------------MSC-RFQSSS-------MSYGG-GFGAGSCQL------
-----------------GG--------------GRNISTCSSRFVTGGSSGGYG------
------------GG------M-SCGFGGGAGGGFG-------------------------
-----GSFGGSYGGGFGG-----GFG--------------------------------DF
GGVDGGLLSGNEKITMQNLNDRLASYLEKVRALEAANADLE---VKIRDWHLKQSPAS--
---PERDYSAYYKTIEELRIKILEATTDNN------------RIVLEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSSQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFQAK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFNSGGNNATTSNGS-PS-----------
--------------STSG---------------------R-------P-----DFRKY--
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
---------------------------MATTFLQ-T--S---S----------TFGGS--
ST------------------------RGASLR-------AGG-G-SFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGFG------
------------GG------M-SCGFGGG----------------------FG-------
---------GGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PDRDYSHYFKTMEEIRDKILAATIDNS------------RVVLEIDNARL-AADDFR
L-KY-ENELTLRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGVITGL-ETQLSELRCEMEAQ--NQEYNML
LDIKTRLEQEIA----TYRNLLEGQDAKM-AGIGVREVSL---GGSSGG-----------
-------GGSSSSSSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
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--------------------------------------------------

------------------------------------------------------------
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--------------------------MASYSFRQTTS-----S----------VAGGP--
-G-------------------------GCSVR-------FGGGS--FRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSGLGSGLG------
------------GG------YGSG-FSSS------------------------------F
GGGFGGGYG----GGLGG------------------------------------------
---GDGLLSGNEKTTMQNLNDRLASYLEKVRALEEANSDLE---TKIRDWYQKQGP-S--
---PARDYSAYHKTIEDLRDQILAATIDNS------------KIVLQIDNARL-AADDFK
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLELQIESLKEELAYLKKNHEE----
-EMSALGGQV-AGQVSVELDSAPGIDLSKILADMRDQYELMAEK-NRKDAE---AWFHSK
----------------TEELN-REVAVNTEQ--LQSSKSEVSDLRRTLQ---GLEIELQS
QLSMK---GALESTLADTEGRYSAQLAHIQDLIGSI-EAQLADLRADMERQ--NSEYKML
MDIKSRLEQEIA----TYRQLLEGQESQM-FGSLSGTA----------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRYS
AGSRLLGFHSG--AGPGRP------S-VGFARSSACGN-SVVGSGF-PCALGGGLG----
----GAPGGSHSTGT----TG-NACVGFAVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKYGP-GSCRGLDHD---YN-NYHLTIEDLKAKIISSTAGNANV
ILQIDNTRLAA-ADFRLKYKNELTLHQNVEADISELRRVLDELTLCRMDRELQYESLSEE
VTYLRK--NHEE----------------------EMKALQCAAGANVNVEVNAAPGVDLT
VLLNNMRAEYEALAEQNRGDAEA--WFGEKSASLQQQMSQDAGEATRARTELSELKRRLQ
TREIELRSLLAT----KHSLECSLSETQGNYCSQLAQIQARISALEEQLHQVRTETEGQK
REYEQLLDVKVHLEKEIETYCRLIAGDEE----SCSKSKSFGSGGSGNSSK-DLSKTTLV
KTVVEELDHRGKVLSSRIHSIEEKTSKLTNKA---EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----SGLG------
------------S-ALGG-SGYSSCYSFGSGG----------------------------
--------------GYGG-----SFG----------------------------------
--GSDGLLAGNEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYKKQAPGP--
---A-RDYSQYYKTIEDLQNKILTASVDNA------------NIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELLYLRKNHEE----
-EMNTLRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--LQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--RVISSREEVH-----
----------------------------------QSPR----------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------------------MATTFLQ-TS-S---C----------TFGGG--
SA------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFMS-GSGEGYR------
------------GS------M-SCGFGGGAGGGFSG-------------G-LG-------
-GGFGGGLGGV----F-------------------------------------------F
GGGDGGLLSGNEKVTMQNLNNRLASYLDKVHALEEANADLE---VKIRDWYQRQSPAS--
---PERDYSRYFKEIEGLRDQILAGDMDNS------------QVILEIDNARL-AADDFR
L-KY-ENELSLRQTVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKRNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQSSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGLIGGL-EEQLAQLRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRRLLEGQDAKM-AGIGTRE-------AALGG-----------
-----------GGSSNFRIKVE----------------ESVDG--KV----------VS-
------S--HKRD---------------V-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGAGG-TFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SSGG--------
------------------------------------------------------------
-----------YGGSYGG-----GAL----------------------------------
-GGSDGLLAGNEKITMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSPYFKTIEDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------TEELN-REVVGHTEQ--LKVSKSEVTDLRRTLQ---SLEIELQS
QLSMK---ASLEGTLAETEARYGAQLAQIQGVISGI-EAQLSDVRADMERQ--NQEYQHL
MDIKSRLEQEIA----TYRSLLEGQDAHY-NNLPTPKG---I------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------------SSR------------------TSCRVS-----
---------------GSLGA----------GSCRL-------GSA-----GGLA------
------------G-ALGS-SNYSSCYSFGSGG----------------------------
--------------SYGG-----SFG----------------------------------
--GGDGLLAGGEKATMQNLNDRLASYLDKVRALEEANIKHE---AALEGWAGG---GP--
---L-RLRLLQHPAGERLGGKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYMKKNHEE----
-EMNSLRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--LQSGKSEISELRRSMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCDMEQQ--NQEYRIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
---------------YGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALQAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILNDMRSQYQVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLPASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTICQFTSS-SSIKG--------SSGLG----
----G-----------------G-----SSH------------------TSCRLS-----
---------------GSLGA----------GSCRP-------GSA-----GGLG------
--------SALG------GSSYSSCYSFGSGGG---------------------------
---------------YGS-----SFG----------------------------------
--GVDGLLAGSEKATMQNLNDRLASYLDKVRALEEANTELE---IKIRDWYQRQALGP--
---T-RDYSQYYKTIE-LQNEILTATVDNA------------NILQEIDNAHL-AAADFR
P-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMHIENLKEELAYLKKNHE-----
-EVRWLGQKV-GGEINVEMDAAPGVDLSRILNEMRDQYEEMAEK-KRKDAE---DWFFSK
----------------TEELN-CKVATNSEL--VQSGKSEILELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETGNRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LVVNTWLEQEIA----TYCHLLEGEDTQDSLASSHD----------------------GN
P-----SSGHPLSYYN--------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----PLRFS
GGSRHIFLQPG--TGSIRLPKA---G-AGFAGNNACGN-SAAGSGF-C--LRGALG----
----RAPGGXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX---XX-XXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXYENELSLHQNVEADITGLRRVLDELTLCKTDQELQFESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRGAEA--WFQEKSATLQQQISDEAGAATTARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCEQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCHLIDGDRN----SCSKSKGFGSGSSGNSSK-ELPKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKTTNGKT--EQRIPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MAATTTSIRQFSTS-GSVKG--------LCVPG----
----G-----------------GFS-RVSSVR--------------VGGA-CRAP-----
---------------SLLGA----------GSCGNMSV-TSSRFS-----AGLG------
--------GGYG-------G----GYTCSLGGGFGS----------------GSGFSAGF
GS------------GFGA-----GFGSG------------------------------FG
--AADALLGGSEKETMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SLVLQIDNARL-AADDFR
N-KY-ETELNLRMTVEADTNGLRRVLDELTLARADLEMQIENLKEELAFLKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLEGSLAETEARYGAQLAQLQGLISNI-EQQLCELRCDMERQ--NNEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAQFPV--------------------------PPP
P-----PPAATVTTRQVRTI----ME------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------L---------------SGSSCRAS-----
---------------SAYGG---------------LSVSCSPRYSSGGV-CGLG------
--------GGV------------------------G--------------GYGGGLGV--
---------------------------G------------------------------Y-
SGGDGSLLPGNEKVTMQNLNGRLASYLDKVHTLEEANRELE---VKTHDWYQSQGPRP--
---A-RDSSPYFKTIEDLRNKTIEATIANA------------HPLL-QDNARL-AADDFR
T-KY-EHELTLRQRVEANISGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMLALRNQI-GGDVSVEMDAAPSVDLSRILNEMRDQYEQIADR-NCRDAE---AWFLSK
----------------SEELN-KEAAFNSEL--MQKSLNELNELRPVLQ---GLEVELHT
QLCMK---ASLEKSLEETQSRYCLQLAQIQERICSV-EEQLAQLCCKMEPQ--NQEYKIL
LDVKAWLEQEIA----TYRRLLEGEDTQ--------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----TSAMS----------SFGGT--
-S-------------------------GGSVR-------IGSGG-VFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRFVTS-ASGN--------
------------------------------------------------------------
-----------YGGIRGG-----SFSG----T--------------------------L-
-AVSDGLLAGNEKITMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYNHYFKTIEDLRDKILGATIGNS------------KIVLQIDNARL-AADDFR
T-KF-ETEHALRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEE----
-EITALRSQV-GGQVSVEVDSTPGVDLAKILSEMRSQYEIMAEK-NRKDAE---ATYNAR
----------------IADLN-IQVDIHTEQ--IQLSKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYGVQLSQKQSVISGF-EAQLSDVRADIERQ--NQEYKQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKV---I------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSKQLDS-------PGRLSGG---G-TSFAAGNPCGV-PGIGSGF-SCVFGGSLSAGGY
APG----------------IGSVPYAAFAGTEHILLAGNEKVTMQNLNDRLASYLDKVRA
LEEANAELEQKIKGWYERFGP-GSCRGLDHD---YS-RYLPIIDDLKIQIISATASNANL
VLQNDNARLTA-DDFRLKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLEMLTEE
LTTLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAET--WFSEKSASLQQQISEDTEAAASAKNELTEIRRSAL
ALQIELQSSVAL----KHSLECSLSETEGNYCTQLAQIQAQIGALEEQLHQVRTEMEGQK
LEYQQLLDIKVHLEKEIETYRRLIDGDE---------------G------------HVIV
KTVVEEIDL-------------QKPSQINK--S--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
---------------YGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHCYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGRVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSE------------GLELELQS
QLSMK---AALEDTLAETEACFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRPEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMKG--------SCGIGGGS-
------------------------S-RMSSVL---------------AGGSCRAP-----
---------------STYG---------------GMSV-TSSRFSSGGA-CGIG------
--------SGYGGSF------SSSSFGGGLGSGFGACGIGSGYGGSFSSSSFGGGLGSGF
GGGLGGGFGGGFGGGIGS--------GI---------------------------G----
----DGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLKSKIITATQENA------------QFTLQIDNARL-AADDFR
T-KY-ENELFLRQSVENDINGLRKVLDELTLSRADLEMQIESLREELAFLKKNHEE----
-EMRALRGQT-GGDVNVEMDAVPGVDLSRILNEMRDQYEQMAEK-NRRDVE---AWFLKK
----------------TEELN-KEVASNSDL--IQSNRSEVAELRRVFQ---GLEIELQS
QLSMH---SSGQS---YSSREVFSSS----------------------------------
------------------------------------------------------------
-------------SRQPRSI----LK------------E--QG--STSFSQSQSQSSRD-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------STYG---------------GMSV-TSSRFSSGGA-CGIG------
--------GGYGGSF----SS--SSFGGGLGSGFGG--------------RF-----DGF
GGGFSAGL--------GG-----GLGGG------------------------------I-
---GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANSELE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KF-ETEQSLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAVPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSS-SQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAAS----------SFGGQ--
-G-------------------------GGLMR-------FGVGG-AYRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSASSSGG--------
------------------------------------------------------------
-----------YGGGYRG-----AVA----------------------------------
--SSDGLLMGNEKVTMQNLNDRLASYLDKVRALEAANGDLE---VKIRDWYLKQGP-G--
---PARDYSQHFKAIEELRDKNLGATIENS------------KVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EISALRGQV-GGQVSVEVDSAPGIDLAKILTDMRSQYEVMAEK-NRKDAE---AWFTSK
----------------TEELN-REVAGHTEQ--LQVSKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLVETEARYGVQLAQIQGLISSI-EAQLSDVRADTERQ--NLEYRQL
MDLKTRLEQEIA----TYRSLLEGQDAYY-NNLLTTKT---A------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
GGSRHICLPSG--TGPVRPPSG---G-SGFAS-STCGG-SVSGSEL-SWALGGALG----
----GVPSGSHAGGA----LGNAACGGFAGSDVGLLSGNEKVTMQNLNNRLASYLDNVKA
LEEANAELERKIKSWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTAANANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQFESLSEE
VTYLKK--DHDE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQISDDAGAATSARTELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCSQLAQIQAQVGALEEQLHQVRTETEGQK
LEHEQLLDIKAHLEKEIETYCRLIDGDGDSCS----KSKGFGCGSPGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKVSASKA--EQRGPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSCSRQYSSS-SSMK---------------GS-
CGLGG-----------------GSS-RVSSVL---------------AGGSCRAP-----
---------------SAYGG----------SGFGGMSV-TSSRFSSGGA-C---------
------------------------------------------------------------
------------------------------------------------------------
----GGLLAGGEKVTMQNLNDRLASYLDKVRALEEANSDLE---IKIRDWYQKQRPTE--
---A-RDYSPYYKTIEDLRNKILTATVDNA------------SVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRVLSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVASNSEL--VQSSKTEISELRRTMQ---NLEIELQS
QLSMK---ASLEGSLEETKGRYCMQLSQIQGLISNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAQKHLTNQ--------------------------
-------HPVTSTSRQVRT-I---VK------------DVHDG--KVVSS--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSSL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYYRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNTLRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------TSPAV---GSLPGCC--LTPHR--
---FPLWQLPYYKTIEDLRSKILVATVDNA------------RILLQIDNARL-AADDFR
T-KF-ETEQALRQSVEADINGLRRVLDELTLARADLEMQIENLNEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EAQLAQLRCEMEQQSQDQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
--------------------------MASYSVRQTSSSS--------------SYRGL--
-G-------------------------A---P-------MGAGRMFAKAPSVHG------
---------------G-YG--------------GQGISVSSAKFVSSGIGGGLG------
------------GG------S--------------------------------------Y
GGGFSSGYGAGSGYGAGS-----GYGA----G-----------------L--------SV
NVSGDVLLSGNEKETMQNLNDRLAMYLDKVRALEEANSGLE---LKIREWYEKQGP-S--
---PSRDYSHYFAIIEDLRGKILDATVDNS------------KIVLQIDNARL-AADDFR
T-KWYENELALRQSVECDINGLRKVLDELTLCRTDLEHQIESLKEELAYLKKNHEE----
-EMNAMRGQV-GGQVSVEVDAAPTVDMNKKLAEMREQYELLAEK-NRRDAE---AWFFSQ
----------------SEELN-KVVATHTEQ--IQTSKSEITDLRRTIQ---GLEIELQS
QLSMK---AALENTLSETEARYGMQLAQIQNVIGSI-EAQLADLRSDMERQ--NHEYKLL
MDIKTRLEKEIS----TYRQLLEGHDAH--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
SASRRLGSCGG--AGSVRLSGG---G-AGFGVGSTGSV-PGFGSGF-TCAFGGSSSAGSY
SGG----------LG----GGSASCTAFTGNEHGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFTVIDDLRNQIISATTSNANI
VLQNDNARLTA-DDFRLKFENEQALHQSVDADVSSLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCAKS----K--GYGGPGHQIK-DPSKATVV
KTIVEEIDPRGKVLSSRVHSVEEKSTKVNNVKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------NAMS---------
-----------------------------LSVRASGLSRRLSS---Q-N----GTAGR--
---------------SRGMSAS--SA-GSS-----YGGS----AFGLGA---G-----Y-
GGGFSA-A---SM--FGSG---SGFGGGSG------------------------------
------------SSL-----------AGGLGTGYGGA-----------------------
------------------------LGGGGFGGLGIGF---GASTG----G--GSL--GLS
SGNDGGLLTGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
SGSQ-SDYSKYYPLIEDLRNKIISANIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRRVLDELTLARADLEMQIESLTEELAYLKKNHE-----
-ELQTFRSGG-PGEVSVEMDAAPGVDLTRLLNDMRSQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEITDLS-ALQ---NLDIELQS
QLAMX---XXLEDSLAETEGDYCSQLSQVQQLIGNL-EAQLVQMRADAERQ--NTEYQRL
LNVKARLEMEIE----TYRRLLDGGPPGDGFDESL---SLTNSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TIVVEEVNGEVVSSQVQEIQELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MSYSLSQSSS-----------------------
------------------------------------------------------------
------------------------------SRMSSGI---SSRLS-DGIYRAAS------
---------------------MQGGYGGSGV-SMSSA-----------KFTSAAGSGMGF
GSGFASGASAGSGAFYGA-----SFS----------------------------------
SGGGDGLLSGNEKYTMQNLNDRLASYLAKVKTLEVANTDLE---AKIRDWYSKQGSVA--
VS-E-QSFGTLYTSIGELRQKILAATINNS------------KLVLEIDNARL-AADDFK
L-KY-ENEFSLRQTVENDISGLRHILDDLTMTRSDLELQIESLKEELIYLKANHEE----
-EVSEKKQHA-AGTVSVELDAVPGVGLLNTLNDLREQYESIADR-NRREAE---AWFLSQ
----------------VEGLQ-KEVVSSTQQ--IQSTKSESTELRRGLQ---SLEIELQS
QLSAK---AGLEASLAETEGRYAAQLFQIQNIISSM-EAQLSDLRSDLERQ--NQEYRTL
LDIKSRLEQEIA----TYHQLLEGQGGLIAAGANSSSG----------------S-SSG-
--S--------TTTR-VHA--IIKEES--------------GG--KVVSSTL--------
--------------------LKS----------F--------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------------------------------------------AYDVT--GT
GGQYDGGFSGNKKETMQNLNDRLANYVDKVRVLEAANAELE---WKINEWYDKQR---ST
SDGG-KDYSKYATLIDDLKLKVCSVEVDVF------------PICVYCELQWV-QGAKYR
L-QY-ENEQILHHSMEAAINTLHRVIDDLTLSKSKLQSQLESLTEELAYLKKNHDE----
-ETKGAPKAT-RGQVSVELKATPGTDLTKILNDMRAQHEALAQK-NRREAE---DRYEKL
----------------SADLK-QRISAGAGR--VQTGKSEISELQRTLR---ALEIELQS
QLAMK---QSLEVTVGKTEGSYCRKLSRIQVTISSI-EEHLAQLKADSESQ--HSQYQQL
LGIKTRLEQEIE----TYRRLLDGEGSKQTR-DLGQ-----------------GR-GSG-
--SG--TNSS--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------VD----------------------LSSNMMS---------
-----------------------------LSVRTSGLPRRLSS---Q-S----GTSGR--
---------------ARGTSAS--LV-GSS-----YGGS----TFGFGD---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------TSLA---GGLGTAYGGTL------------------------------
-----------------------GGLGGGFGGLGIGF---GGSPG----GS-GAV--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEAANTELE---NKIREWYETRGSGTGD
SGSQ-NDYSKYYPLIEDLRNEIISASIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALHQSVEADINGLRRVLDELTLARADLEMQIENLTEELAYLKKNHEE----
-ELQSFRAGG-PGEISVEMDAAPAVDLTRLLNNMREQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISSNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLATK---KSLEVSLAEVEGDYCGQLSQVQQLISSL-EEQLLQVRADTEHQ--NADHQRL
LDAKARLELEIE----TYRRLLDGEAQRDGFDETL---YVTESKPQ--------------
----------------------------------------TQSI-G--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDQTK-------S-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVQEELM------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTSFLQ-TS-S---S----------TFGGG--
ST------------------------RGASLL-------AGG-G-GFGGRSVSG------
---------------G-GG--------------SRSISASSARFVSSGLGGGHG------
------------GG------M-SCSFGGGAGGGF--------------------------
GGGYGGGLGGGFGGGFGS-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQSPSS--
---PERDYSHYYKTIEELRDKILAASIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADTNGLRRVLDELTLARTDLEMQIESLNEELAYMKKNHEE----
-EMKEFTNQV-AGQVNVEMDAAPGVDLTRVLAEMREQYEAIAEK-NRRDAE---AWFSQX
----------------XXXXX-XXXXXXXXX--XXXXX-XXXXXXXXXX---XXXXXXXX
XXXXK---AGLETSLAETECRYVMQLQQIQGIISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDARM-AGITTREASL---GGDG-------------
--------------GKVRINVE----------------ETMDG--KV----------VS-
------S--HKRE---------------V-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANAELE---VKIRDWYQRQAPGP--
---A-RDYSQYHRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMTALRGQA-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------RQLAGFQDTLSKNTMSSYSIRQTTTSSGSMK----------GLGGF--
-G-------------------------GGSSR-------V--SG-VYRAPSIHG------
---------------G-SG--------------GQNVSISSTRVMSGM-GGGYG------
------------SC------G--------------------------------------V
DAGLGGGYMSNYGGGYGS-----GYV-----F-----------------G--------GG
VAGGEGLISGSEKYTMQNLNDRLAAYLEKVRSLEKANGELE---IKIRDWYQKQAP-G--
---PAADYSHYYKTIEDLRNKILSATMDNA------------GLLLQIDNAKL-AADDFR
T-KY-ETELALRMNVEADINGLRRVLDDLTINRSDLEIQIESLKEELAYLKKNHEE----
-EMIALRGQA-TGQVNVEMDAAPSSDLTKTLAEMRIQYENLAEK-NRRDVE---EWFFKK
----------------TEELN-KEVANSSVM--IQSSKTEITDLKRTLQ---SLEIELQT
QLSMK---AALEGSLAETEGRYCVQLSQIQGLISSV-EAQLGELRSDMERQ--SHEYKIL
MDVKTRLEQEIA----TYRRLLEGEDAHI-SYKDTLLIKSSIPSSRTFSVFLS-------
------QKDGPKTTRQVRTIVQ----------------ETVNG--NVVSSR---------
------EDVRKLP---------------Y-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GIEIELQS
QLSMK---AALEDTLEETEARFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-----------------------------MSVRYST-SKQFSS---SRS----GGGGG-G
-------------------GGGGSSLRISNSKVS-------------HGGGFS-----S-
-GGFSG-G---SF--SRGSSSGGCFGGSSG-GYGG---------------------SL--
-G-------GFGGGSF---GG---GFGGG---SFGGGYG-------------GGSFG---
-GSSFGG---------------GSFGG-------GGY--------------GGGFG-GGY
GGGDGGLLSGNEKVTMQNLNDRLASYMDKVRALEESNYELE---GKIKEWYEKHGNA--G
QREP-RDYSKYYQTIEELKNQILTLTTDNA------------NVLLQIDNARL-AADDFR
M-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEK-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGSYGGGRGGG-G-----------GG-----
---------------SYGGG--SS---SGGGHGGSSGGG---------------------
----------------------------------QGGSYGGGSSSGGGHGSS----SGGG
LG-GSSGGGHGGSYGG-GSSS----------------------GGQSGSGGFKSSSS-GS
AGD---QSSKGPRSAETSWGNQ-----------------N--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------MFCSAQKGSCS-------SRVSS------------SGA-V
---------------GSRGCTG------SGSSYGLGGGS----AWGFQGSS-S-----S-
----------------------WGLSGGSKGS-----------------------IGGGF
SSCSVR--GGFGAGSS-----------------F--------------------------
----------------GG---GSGFGGGSSGG----VSSYGG--S-----LGGGLG-G-I
GGYDGGLLSGSEKQTMQGLNDRLANYLDKVRALEEANTDLE---TKIKDWYGRHGSG--K
DGPG-RDYSQYCSVIEDLKNQIISATCENA------------RLALQIDNARL-AADDFR
M-KY-EHELCLRQSLEADINGLRKVLDEMTMTRCDLEMQIEGLTEELVFLRKNHEE----
-EMKCLQGSS-GGDVTVEMNATPGTDLTKLLNDMRAQYEAMAEQ-NRQEAE---KQFNER
----------------SACLQ-AQISTDAGA--ANCAKSEVMELRRTVQ---TLEIELQS
QLALK---CSLEGTLADTEARYVAQLSGIQTQISSL-EEQLSQIRGETQCQ--SAEYECL
LDIKTRLEQEIE----TYRRLLNGDGGGC-------DYRNLVSRQ---------------
-----------------------------------------------------------V
V-----------------------------------------------------------
---------------------------------------------------LNDSNF-GS
C----SGQEKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQVSNI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSL-RLQNSS-------ASYGG------ACQL------
---------------G-GG--------------RGMSSGCSSRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
GGGFGGGFGGGCGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSHYYKTIEELREKILAATIDNN------------RVILEIDNSRL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQM-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHSK
----------------SAELN-KEVSSNTEM--IQTSKTEITELRRTLQ---SLEIELQS
QLSMK---AGLESTVAETECRYATQLVQIQDLISSM-EAQLSEVRADTERQ--NLEYRQL
MDIKTRLEQEIA----TYRSLLEGQDAKM-TGFPSSGAQMALSPRATPEH----------
-------L----SPPCFPGTTS-----------------S-------G-----TARRPS-
------EVTTRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------A------P-----
---------------SAYG---------------GLSV-TSSRFSSGGA-CGMG------
--------GSYGGGF----SSS-SSFGGGYGG--FA--------------GYG----GGL
GA----GLGAGLGGGLGG-----GFGVG------------------------------F-
GG-GDGLLAGSEKVTMQNLNDRLASYLEKVRALEEANAELE---VKIRDWYQRQRPVE--
---N-RDYSSYYKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNTMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRRDAE---EWFFSK
----------------TEELN-REVATNTEA--LQSSKTEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDMIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------AQ--FSSGSQSSR-
--------DVTSSSRQVRT-K---VV------------DVHDG--KVV------S-----
---------SHEQ---------------I--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------------------------------M-----SVSFS
SASKQLGS-------PGRLSEG---R-PSFPAGNPCGV-PGIRSGF-SCAFGGSWSAGGL
--G----------------TGSASCAGFAVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLQNQIISATTSNAGV
VLQNDNARLAA-DDFRLKYENELALHQSVDADINGLRRVLDELTLCRADLEIQLETLTEE
LAHLKR--NHEE----------------------EMKALQCAAGGNVNVEVNAAPGVDLT
VLLSNMRAEYEALADQNRRNAEA--WFSEKSASLQQQISEDIGSATSAKNELLEMKRMAQ
GLEIELQSSVAL----KHSLECSLSETKGNYCSQLAQIQARIAALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDKESCFKS----K--GQGGPGSQIK-DASKPAVV
KTVVEEIDPRGNVFRSRIHTIEEKPTKVNT--S--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------------SSR------------------TSCRLS-----
---------------GSLGG----------GSCRL-------GSA-----GGLA------
--------GALG------SSNYSSCYSFGSGG----------------------------
--------------SYGG-----SFG----------------------------------
--SSDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKRAPGP--
---A-PDYSHYWKSIEDLKNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYMRKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRSLQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCDMEQQ--NQEYRIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEXXXTRQVRTI----VE------------EVQDG--RVISSREQVH-----
----------------------------------QTTH----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFASS-GSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------GGGSCRAS-----
---------------NAFGG--------------M----SSSRYS-------TG------
--------GGMGGGF----SR-SSSYGGGLGGGFGG--------------GYDGVFGFFG
GN----YGGDRYPAGYGG-----GFGSS------------------------------L-
GS-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---V-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADTNGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKIAEK-NRKEAE---EWFFTK
----------------TEELN-REVATNSEL--VQSSKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQEMIGSV-EEQLAQLRCDMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSHSSR-
--------DVSSSSRQIRT-K---VV------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSLRSSS-SKHYSF---PIQ----GGGGGGG
-------------------GGGGSSFRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSS-GGCLGGSSS-GYGI---------------------SGGF
GGSSFG--GGYGSSSF---GG---GYGSS---SFGGGYG-------------GGSFS---
-GGSFGGGGFGGG--FGG----G-----------------------------FG---GGF
GG-DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--R
QGEP-RDYSKYYKTIDDLKSQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLAKADLEMQIESLTEELAYLRKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKTEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGYGGG--------------------
----------------------SS---GGGYGGGSYGGGSSG-G-GYGGGSS--GGGGGS
YGG--------------------GSSG------GGGGSYGGGSSGGGGG--S----SGGG
YGGGSSGGSSGGGF-----------------------------GGGSSSGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MPCS-------SRVSS---S-------RAGGSS
---------------SVRVSVGRSSF-SSGS-SGLGGSS----TRGFRGGT-S-----S-
----------------------CGLNGGSSSGFRGS-------------------FGGGF
ASCSVG--GGFGGSS---------GFGGGAS--FGGGS----------------G-----
---------FGRGSGFSG---GSEFGSSSGGG----FYSYGGG-------M----E-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKFGPGSRD
SASG-RDYSKYYEITEDLRNKIITATIENA------------GIVLQIDNGRL-AADDFR
L-KY-ENELYLRQSVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMRSLQGSS-GGDVSVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKSEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQMLISSL-EGQICQVRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYHRLLDGERGGS-------GFGEFDYRNS--------G-----
------------S-RNT----G--------------------SR-D-------------S
G-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDP---SK----T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQVSNV----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RMSSIL---------------AGGSCRAP-----
---------------STCGG---------------MSV-TSSRFSSGGV-CGIG------
--------GGYGGSF----SS--SSFGGGLGSGFGG--------------RFD-GFGGGF
GAGLG------------G-----GLGGG------------------------------I-
---GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLKSKIIIATQENA------------QFTLQIDNARL-AADDFR
T-KY-ENELFLRQSVEGDINGLRKVLDELTLSRADLEMQIENLREELAFLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDVE---AWFLRK
----------------TEELN-KEVASNSDL--IQSNRSEVAELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLISSV-EEQLAQLRCEMEQQ--SQEYNIL
LDVKTRLEQEIA----TYRRLLDGENIHSS-SQH-SSGQSYSSR--EV--FS--------
-----------SSSRQPRSIL---KE------------QGS---------TSFSQSQSQ-
------SSRD--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSQRYGS-SRHYSS---SRS----GGGA---
--------------------GGGSSIRISSTRGSGYGA-------GSIGGGFS-----S-
AGGFGS-----------------------------R-------------------SVGGF
VGG-------FSSSSY---G----------GGSFGGSYGG----VS----CGGGSFG---
---------------------------------------------------------GLF
DGSDGGLLSGNEKVTMQNLNDRLASYLDKVKALEDSNSQLE---QKIKEWYEKYGNS--R
QREP-RDYSHYYDVIKDLKDQILTLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALHQSVEADINGLRRVLDDLTLAKTDLEVQLESLNEELAFLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTENLNLLRSQYEQLAEQ-NRREAE---AWFNEK
----------------SKELT-TEINSNVEQ--VSSQKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCSQLSEIQAQITAL-EEQLQQVRAETEYQ--NSEYQLL
LDIKIRLENEIQ----TYRSLLEEGGSANSAAIGHGGSSGGT------------------
----------------YRGISGGVQ--GASSSSGAYGGSSAGSG-GVTSSG---------
------------------------------------------------------------
--------------------------------------------SRRGSSVVQGGSS-GS
GGESTSKSSSGTRF----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------QRVLPCPQH---------------------LRGSL-
---CV-------------------------------------------------------
---------------------------------------SFSRFSFGGA-CGLG------
--------GGYGGGF------SSSS-------------------------RYGGGLGAGF
GGGLGA--------------------GL---------------------------G--GG
FAGGDGLLVGSEKVTMQHLNDRLASYLDKVRALEEANADLE---VKIRDWYLRQRPSE--
---I-KDYSPYFKTIEDLRHKIIAATIENA------------QPILQIDNARL-A-----
-----EHELALRQTVEAGINGLCRVLDELTLARTDLEMQMEGLKEELAYLRKNHEE----
-EMLALRGQT-GGEVNVETDAAPGMDLSCILNEMRNQYEQMAKQ-NHRDAE---AWFLSK
----------------TKELN-KKVASSSEL--VQSSRSEVMELQRVFQ---GLEMELQS
QLSIK---ASLENSLEETKGCYCMQLSQIQGLIGSV-EEQLAQLSCEMEQQ--SQEYQIL
LDMKTRLEQ-IA----TYCRLLEGEDAHLSSPHASGQS--CSSR--VV--F---------
------TSSSSSSSRQTWPI----LK------------E--QG--SSSFSQGQCS-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
C-------------------------RLQGSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRSISTCSTRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGFGG------GAGS----GFGGGF
GGGFGGGFGGGFGGGFGG-----GFG--------------------------------DY
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANTELE---VKIRDWHLKQSPSS--
---PERDYSPYYKTIEELRDKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQM-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHSK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLADTECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDARM-AGLTSSGGKETTLEGS--------------
-------T------SVS-IT-------------------T-------T-----SSSRTS-
-------D-TRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----GGL
GA--------SFGGGLGG-----GLGSG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLRKNHEE----
-EMNSLRGQV-SGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------ST---------SQ--FSSGSQSSR-
--------DVTSTSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRIVSGGSAGGYG------
------------SG------V-SCGFGGGI------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LTATIENH------------QVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSSA-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----GGLG------
------------S-VLGG-SGYSSCYNFGSGS----------------------------
--------------AYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSHYYQTIEDLKNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADTNGLRRVLDELTLSRADLEMQIENLKEELAYLRKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGACRAP-----
---------------SAYG---------------GLSV-STSRYSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGGLGSGFGG--------------GYGGGLGAGF
GG----GLGAGFGGGLGA-----GFGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADTNGLRRVLDELTLSRADLEMQIETLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDLIGNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
SI------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------R-GG--------------SQSISASSARFVSSGSGGGYG------
------------GG------M-SCGFGGGAGSGFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQAPTS--
---PERDYSHYFKTIEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFNSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEMVSNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLISGL-EAQLSQLRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGVGIREASL---GGGGG------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQTSS-STFGG----------GSTRGGS
LR--A-----------------GGG-GFGGGS-------LYGGG-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------M-SCGFGGAAGAGFG-------------------------
---------GGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSVNEKVTMQNLNDRLASYLDKVRALEEANGELE---VKIRDWYQKQSPSS--
---PERDYSQYYKTIEELRDKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMRAQYEALAEK-NRRDAE---EWFNSK
----------------SAELN-KEVSSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTVAETECRYALQLQQIQGVISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFTSTGGSGATSGSG--------------
-------------------------------------------------------RRIS-
-------DTTRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MAA-----ALG----------------------------------
--ALMGCW---------------PEVRRPPCRTSMTNTELE---VKIRDWYQRQAPGP--
---T-RAYSQYYRTIKELQNKILTATVDNA------------YILLQIDNAHL-AAADFR
T-KF-ETEQALHLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQM-AGEINVEMDAAPGMDLSRILNEMRDQYEKMAEK-NRKDAE---GWFFSK
----------------TEELN-CEVATNSKL--VQSGKSEILELWRTMQ---ALEIKLQS
QLSVK---ASLEGNLAETENCYCVQLSQIQGLISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTWLEQEIA----TYHRLLEGEYAHLTQY----------------------------
-------KKEPVTTRQVCTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYG---------------GLSV-SSSRFSSGGA-CGMG------
--------SSYGGGF----SSS-S-FGGGYGGGIGG--------------GIGGGFGGGF
GG--------GFGGGIGG-----GIGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---I-KDYSSYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIETLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLSQIQEMISGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-STQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRHFSS--GSIKG--------SSGLA----
----G-----------------G------SS------------------RSCRVS-----
---------------GSLGG----------GSCRL-------GSA-----GGLG------
------------S-GLGG-SSYSSCYSFGSGGSYGS--------------G--GY----V
SG------------GYGG-----GFG----------------------------------
--GVDGLLVGGEKATMQNLNDRLASYLDKVRALEEANTELE---LKIRDWYQKQAPGP--
---A-PDYSSYFKTIEDLRNKIHTATVDNA------------NLLLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMKALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTLQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
T-------KEPVTTRQVRTI----VE------------EVQDG--RVISSREQVH-----
----------------------------------QTSH----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLP
SGSRRAGPRP--TTGSLRLSGA---G-ASFGAGNACSM-PGIGSSF-SCAFGSSS-SGGN
A------------------LGGNPCAGFTMNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQITEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYAAGNMGNQMK-DPIKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNSSMS---------
-----------------------------LSVRTPGLPRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGA---S-----S-
GGGFSA-A---SM--FGSS---SGFGVGSA------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGGGFGGLGLGF---AGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGAGD
S-SQ-NDYSKYYPLIEDLRNKIISASIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTMTRTDLEMQVESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLDES---LFVTDSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG---------------LSV-SSSRFSSGGA-CGIG------
--------SSYGGGF----SS--SSFGGGYGAGLGG--------------GF--------
GGGFG------------G-----GFGG---------------------------------
---GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLKSKIIAATLENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDVSVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQGLIGGV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLDGEDAQISS-QH-SSGQSYSS--REV--FS--------
-----------SSSRQPRSIL---KE------------QSS---------SSFSQSQSQ-
------SSRN--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAVS----------SFGGF--
-G-------------------------GGSVR-------FGSGG-VFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRIVSS-SSGS--------
------------------------------------------------------------
-----------YGGGYGG-----SFGG----N--------------------------L-
-AVSDGLLAGNEKLTMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---TLFITR
----------------TEELN-REVASHTEQ--LQMSKSEVTDLRRTLQ---SLEIELQS
QLSMK---AALEGTLAETEARYSAQLSQIQAVISSI-EAQLSSVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKA---I------------------
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-------------------------------------------------------GGGGG
GGGGG-------------------------GGGGGGGGG--GGG-GGGGGGGG-G-----
-----------GGGGGGGGGGG---GGGGGGGGGGGG---GGGGG-GGGGGGGGGGGG--
-------------GGGGGGGGGGGGGGGGGG-GGGGGGGG---GGGGGGGGGGGGGGGGY
GAGFG------------A-----GFGGG--------------------------------
FGGGDGILPAGEKETMQNLNDRLATYLDKVRALEEANTELE---VKIREWYKKQAPG---
P--D-RDYSPYYRTIEELRNKILSATVENA------------NIVLQIDNARL-AADDFR
T-KF-ESEQALRLSVEADINGLRRVLDELTLSRADLEMQIENLKEELTYLKKNHEE----
-EMTALRGQV-GGEISVEMDAAPGIDLTKILAEMREQYESLAEK-NRRDAE---QWFFSK
----------------VEEVN-LEVVTSSQE--IESSNKQVTELRRQLQ---ALEINVQA
QLTMK---ENLESSLTETECRYNKYLAELQNQISCV-EQRLAEIRAEMECQ--NQEYKTL
LDVKCRLEQEIQ----TYHCLLEGGQHDIMGGGGGGGG----------------------
---------------------G---GGGGG-GGGGGGGGGGGG--GGGGGGG-GGGGGG-
--------------GGGGGGGGGGG------GGGGGGGGGGGGGGGGG---G--------
-GGGG---GGGGGGGG-GGGGGG----------GG---G---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------GG-----------GGGGGGGG--------------
GGGGGGG------------------------GGGG----G--GGG---GGGG-G--G-GG
GG--GGGGGGGGGGGGGGGGGGGGGGGG-----GGGGSSVHD------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCSIKQ-TT--GSLR--GRTSGGSCVVGGG--
GGGAR-------------------------------------------------------
------------------ISSV---SSGRYTSCGIGG---SRGFS-GRSYCGGVN-YG--
-------------GGLSTGSLVGGNYGGGLG-AAVLGGCP---GMGFSGGSA--RFGGGM
GGGMG------------M-----GLG----G---------------------------GG
FAGDGILLSGDEKVTMQNLNDRLASYLDKVRCLEQENADLE---CRIREWYAKQGPFC--
E--P-RDYSCYYKEIEDLQNQIVCATIDNN------------KIILNIDNSRM-TADDFR
V-KY-ETELALRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEE----
-EMCCLRKQS-TGDVSVEVNACPGPDLRKILEEMRCQYETLIER-NRKEVE---DWYECK
----------------IEEVN-REVITSGQE--VETCNNQVTELRRQLQ---ALEIDLQA
QLSQR---DNLESSLAETECRYNNHLAELQSQITCV-EQQLADLRAEMECQ--NQEYKIL
LDVKCRLEQEIH----TYRCLLEGGQQDLIQQG-GIGQ----------------------
---------------------S---SGLGG-GVARSSGIGGGG--IIRTSHT-YTS----
-----------------SAQIPSC------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------AAAEI-----QVPCRRICD------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCNIKE-TI-TVSSK--GRSSGGSCIIGGGGA
A---R-------------------------------------------------------
-----------------------------ISSFGIGS---GRGFS-GRSYCGGVN-YG--
-------------GGLSVGSLAGGSYGGGN----------------------------CY
GNGLG------------F-----GLGGGVVV---------------------------GG
LGGDCLLSSCDEKVTMQNLNDRLASYLDKVKCLEKENAELE---CRIREWYATQGLSC--
E--P-RDYSCYYKEIEDLQNQIVCATIDNN------------KIILDIDNSRM-AADDFR
V-KY-ETELALRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEE----
-EMSCLRKQS-TGDVSVEVNACPGPDLRQILEDLRCQYETLIAR-NRKEVE---DWYECK
----------------IEEVN-REVITSGQE--VETCNNQVTELRRQLQ---TLEIDLQA
QLSQR---NNLESSLAETECQYNTLLGELQNQITCV-EQQLAEIRAEIECQ--NQEYKTL
LDVKCRLEQEIQ----TYRCLLEGGQQDLIHGG-GIGT----------------------
----------------------------GG-G-------------VIRTSHT-YTTTTA-
--------------AHCQPQVPPC------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------KTGDI-----QVTCRRICD------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------SFGGG--
ST------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSAGSGAGYG------
------------SM------M-SCGFGGGAGSGFGG-------------G----------
---------SGFGGGFGG-----G-----------------------------------F
GGGDGGLLSGNEKATMQNLNDRLASYLDKVRALEEANAELE---VKIRDWYQKQAPTS--
---PERDYSPYFKTIEELRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-EHELTLRQSVEADINGLRRVLDELTLARTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRELAGMREQYEALAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGSI-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGIPGAAL---GSGGG------------
-----------SSSSNLHIKIE----------------ESVDG--RK----------LS-
------S--RQRE---------------T-------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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----------------------------------------------------------MS
C-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRNVSACSTRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGG----------------------F
GGGFGGGLGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKLTMQNLNDRLASYLDKVRALEEANAELE---VKIRDWHLKQSPSS--
---PERDYSAYYKTIEELRDKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSSQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHSK
----------------SAELS-KEVSSSTAL--IQTSKTEITELRRTLQ----LEIELQS
QLSMK---AGLESTVADTECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKTL
LDIKTRLEQEIA----TYRSLLEGQDARM-AGVTASGGLSVPCPLHSSGS----------
-------A------GVT-VTTS----------------TS-------S-----SSRRLS-
-------DTRKL------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------MTSYSYRQ----SSATS----------TFGGM--
-G-------------------------SGSVR-------FGAGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SSGG--------
------------------------------------------------------------
-----------YGGSYGG-----GYGG----V--------------------------Q-
-AVSDGLLAGNEKITMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYFKTIEDLRDKIQGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLSRTDLEMQIEGLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEK-NRKDAE---AWFITQ
----------------TEELN-REVAGHTEQ--LKMSKTEITDLRRTLQ---SLEIELQS
QLSMK---AALEGTLAETEARYGAQLAQIQGVISSI-EAQLSDVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRNLLEGQEAHY-NNLPTPKA---M------------------
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--------------------------------------------------------LCRQ
AG-------------------------VQWQV-------MSAHC-------NLC------
---------------L-LG--------------SSPSPASASRLAGIAGTTGLI------
------------FV----------------------------------------------
-----------FLVEMDG-----V------------------------------------
PAASDRLLEGNEKLTMQNLNDRLASYLDKVRALEAANCELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLQDKLLGATIENS------------RIVLEIDNARL-AADNFR
T-KT-DTEQVLRMTVEADINGLRRVLGELTLASTVLEMQIEGLKEELAYLKKNHEE----
-EISGLRGQV-GGQVSVEVDSARGTDLARILSDMRSQYKVMAEQ-NWKDAE---AWFTSR
----------------TEELN-REVAGHTDQ--LQMSLSKVTDLRHTLQ---GLE--LQS
QLSMK---ATLEGTLAETEARVGAQLAQIQSLINGI-EVQLGDVRADSERQ--NQEYQQF
TDNKSRLQQEIA----TYRSLLEGQEYHY-NNLSASKVL---------------------
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--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGG----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSHYYRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQM-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
HLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTH----------------------
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-------------------------NMTTCSRQFTSS-SSMKG--------SCGLG----
----G-----------------GSS-RFSTVL---------------TGGSCRAP-----
---------------STYGG---------------LSV-SSSRFSSGGA-CGIG------
--------GGYGGGF----SS--SSFGGGLGSGFGG--------------GFGGGFGGGF
GGGLG------------G-----GFGG---------------------------------
---GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLKSKIIAATLENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---SLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQGLISSV-EEQLAQLRCEMEQQ--SQEYNIL
LDVKTRLEQEIA----TYRRLLDGEDVHSSS-QY-SSGQSYSS--REA--FS--------
-----------SSSRQPRSIL---KE------------QGS---------SSFSQSQSQ-
------SSRN--------------------------------------------------
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---------------------------------------------------------MKA
QGNGRCQA-----------------RPLPMSIKHSH--------PFSAYLAPSLLSA---
--------------NC-SLAHLLLNTMTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYG---------------GLSV-STSRFSSGGA-YGLG------
--------GGYGGGF----SSS--SYGG----GFGG--------------GYGGGLGAGF
GG--------GLGAGFGG-----GLGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLISGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKMAGIGIREASLG------G-------------
G-----G-G--SSNFH---IN---IE------------ESVDG--KVVSS--RKR-----
---------EI-------------------------------------------------
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--------------TMQNLNDRLAAYLDKVRALEDANTDLE---VKIREWYKKQGPGP--
---E-RDYSPYYRTIEELRSKVLGATVDNA------------NLLLQIDNARL-TADDFR
T-KF-ETEQALRLSVESDINGLRRVLDELTLSRADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEISVEMDAAPGIDLTKILAEMREQYESLAEK-NRRDAE---QWFFSK
----------------TEELN-REVAINTEQ--LQSGKTEITELRRTIQ---SLEIDLQS
QLSTK---AALEGTLADTEARYGTQLAQLQALITSV-EEQLAELRCDMERQ--NHEYRVL
LDVKCRLEQEIA----TYRRLLEGEDAHMTSHYASQTVKEVVKVWVGANPGTALPYRTVP
S-----PLAGPVTTRQIRTI----FE------------EVQDG--KVISSREQIT--QA-
--------------------------------AL--------------------------
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-----------------------MAATTTSFRQFSTS-GSIKG--------LGMPT----
----G-----------------GFS-RVSTVR--------------VGGA-CRAP-----
---------------SLLGA----------GSCGNMSV-NSSRFM-----AGMG------
--------GGYS-------G----GYSCNLGGGYGS------------------------
---------------------------S------------------------------YS
--VSDALLGGGEKETMQNLNDRLASYLEKVRALEEANADLE---VKIRDWYKKQGPEP--
---A-RDYSHYFKVIEELKSKILAATIDNA------------SLVLQIDNARL-AADDFR
T-KY-EMELNLRMSVEGDTNGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKIAEK-NRKEAE---DWFFTK
----------------TEELN-REVATNTEA--LQSHRTEISELRRSVQ---NLEIELQS
QLSMK---ASLEGSLAETEARYGAQLAQLQGLIGSI-EQQLGELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLANQYSS-FL-------------------ASQ
P-----TREATVTSRQVRTI----VE------------EVQDG--KVVTSREQVH--RS-
--------------------------------TH--------------------------
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-------------------------------------------------M-----SLRFS
GGSRHVGLQS----GSLRPPSG---G-AGFAGGSAGGS-SAAGSGF-SWALGGTLS----
-----APGGSHAPGA----LGNAAAVGFSGNEGGLLSGNEKVTMQNLNSRLASYLDNVKA
LEEANTELERQIKNWHEKYGP-GSCRGLDND---YS-RYHLTIEDLKSKVISSTAANANI
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDHELQYESLSEE
MTYLKK--NHEE----------------------EMKVLQCSAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEGLAEQNRRDAEA--WFQEKSATLQQQISNDMGAATSARTELTELKRSLQ
TLEIELQSLSAT----KHSLECSLAETEGNYCSQLAHIQAQISALEEQLHQVRTETEGQK
LEHEQLMDIKAHLEKEIDTYCRLIDGDENSCS----SAKGFESGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKMSKMSNGKA--EQRVPF---------

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----------------------MSC-RLQTSS-------SSYGA-GYGGGSCQL------
-----------------GG--------------GRSFSTCSTRFASGGSAGGYG------
------------AG------M-SCGFGAGAGSGFGGGY----------------------
----GGGFGGSFGG---------GFG--------------------------------DF
GGGDRGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQSPVS--
---PERDYSRYYKDIEELRAKILAATTENN------------QVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLRKNHEE----
-EMKEFSKQV-VGQVNVEMDATPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFQSK
----------------SAELN-KEVASNTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLEGTLAETECRYALQLQQIQGLISGI-EAQLADLRAETECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDARL-AVSASSAGS----GSATSNV----------
-------S----------GSG------------------SP---------RR------S-
------D-IRRF------------------------------------------------
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------------------YENELALHQSVEADVNGLRRVLDEITLGKTDLEIHYETLNEE
ITYIKR--NHKE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
ILLNNMRAEYEGLAEQNRRNVEA--WFNEKSASLQQQISEDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCEQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLLGGDDGACKSGGYKSKDYGSGNVGNQIK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSPNN----------------------

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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGAATSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
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---------------MQNLNDRLASYLDKVRALEEANAELE---VKIRDWYQKQAPGP--
---A-RDYSHYYRTIEDLQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDEMTLARADMEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIT----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--RVISSREEVH-----
----------------------------------QTTR----------------------
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--------------------------MTTCSRQFTSS-SSMKGS--------CGIGS---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----GGL
GA--------GFGGGLGA-----GFGGG------------------------------F-
AG-SDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------ASCRLS-----
---------------SSLGG----------GSCRL-------GSV-----GGLG------
------------S-ALGG-SSYSSCHSFGSGG----------------------------
--------------SYGG-----SFG----------------------------------
--GVDGLLGGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSHYYHTIEDLKSKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMTALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEIAELRRTVQ---TLEIELQS
QLSMK---ASLEGSLAETENRYCVQLAQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYRIL
LDVKTRLEQEIT----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFVAGNVCVG-SGAGSSF-SCTLGGISS----
----GGSFC-NSGGG----LGSGACSGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVRA
LEEANADLEQKIKGWYEKCEP-GSSRGHDHD---YS-RYFSVIEDLKRQIISATTCNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIHCETLSEE
LTHLKK--NHEE----------------------EMEVLQCTAGGNVNVEMNATPGVDLT
LLLNNMRAEYEDLAEQNCKDAEA--WFNERSATLQQQISNDEGAATAARNELTELKRNLQ
TLEIELQSLMAV----KHSYECSLAETEGNYCNQLQQIQDQIGVREEQLQQIRTETEGQK
LEYEQLLDVKIFLEKEIEIYCNLLDGEERKSKSTCYKSKGCRPVNSGNQGK-DSAKETIV
KTVVEELDQIGSVLSLRVHSVEEKSSKISNITV--EQRVPSKAP------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSHS-------TRVSS---S-------RAGGSS
---------------SARVSGGGSSF-SGGSRCGLGGSS----ARGFRGGA-G-----S-
----------------------CGLSGGSSSLWR--------------------------
---------GFGSSSG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSS---GG----FYSYGGG-------M----R-G--
DVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDDSKYYSIIEELRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADISGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQISAL-EEEICHLRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGG-
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLGGF
GGGSFR--GSYGSSSF---GG---------------------------------GYGGSF
GGGSFGGGSFGG----------GSFGG-------GSF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGEP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--ISSYKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSFGGG-------------------
----------------YGGG----------GG----------------------------
------------------------------------------------------------
---------------------------------------------GSSSGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGAGNTCGV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKN--EQRVSS---------

------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLGSCGG--AGSLRLSSG---G-SGLGAGNACGV-PGIGSGF-SCAFGGGSVAGGY
GGG----------LG----GGSAPCSAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEQYGP-GSCRGLDHD---YS-RYFPIIGDLKNQIISATTSNASV
VLQNDNARLTA-DDFRMKFENEMTLHQSVEADINGLRRVLDELTLCRNDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNERSASLQQQISDDEGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLGIKVLLEKEIETYCHLIDGEDGSCFKS----K--GHRGPGSQTK-DSSKAAIV
KTVVEEIDSRGKVLSSRVHTTEEKATKA-NTKS--EPRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTICQFTSS-SSIKG--------SSGLG----
----G-----------------G-----SSR------------------TSCRLS-----
---------------GGVGA----------GSCRL-------GSA-----GSLG------
--------SALG------GSSYSSCYSFGSGGG---------------------------
---------------YGS-----SFG----------------------------------
--GIDGLLAGGEKATMQNLNDGLASYLDKVCTLEEASTELE---VKICDWYQRQAPGP--
---A-SDYSQYYRTIEELQNKILTATVDNA------------NILLQIDNAHL-ATADFR
P-KF-ETEQALRLSVEADINGLHRVLDELTLARADLEMHIENLKEELAYLKENHE-----
-EVRWLGQKV-GGEINVELDAAPGVDLSRILNEMHDQYEEMADK-NRKDAE---DWFFSK
----------------TEELD-CEVATNSEL--VQSGKSEILELRRTMQ---ALEIELQS
QLNMVGTSSSLEGNLAETENRYCMQLSQIQGLISSV-EKQLAQLRCEMEQQ--NGEYKIL
LDVNTWLEQEIA----TYRHLLEGEDAHEGLLAPTH-F--------------------KV
P-----ASPAAVTTRQVCSI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGG-
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLGGF
GGGSFG--GSYGSSSF---GG---------------------------------GYGGSF
GGGSFGGGSFGG----------GSFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSYGGG-------------------
----------------YGG-----------GS---SGGGSSGGG-Y-------GGGHSGS
SGGGYGGG---SSGGGSSGGGYGGGSSSGGYG--------GGSSGGG---HG--------
-------GSSGGG-HG-GSSGGG-------------GSSGGGFGGGSSGGGHKSSSS-GS
VGE---SSSKGPRSAETSWGNQ-----------------N--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---A-TSFGAGNSCGI-SGIGSGF-SCAFGGS-SSGGN
T------------------GGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTSNRQFSSS-NSIRG--------SSGLG----
----G-----------------SSS-----L------------------TSRQLS-----
---------------GSLG-----------------------------------------
--------NA-----L-GGGSYSGCYSFGSGGG---------------------------
---------------YGS-----GFG----------------------------------
--GGDALLGASEKATMQNLNDRLASYLEKVRALEEANTDLE---VKIRDWYQKQTPGP--
---T-SDYSAYFKTIEDLRNKILMATTDNA------------NVLLQIDNSRL-AADDFR
T-KF-ETEQALRVSVESDINGLRRVLDELTLARADLEMQIENLKEELVYLRKNHEE----
-EMKVLRGQV-GGEINVEMDAAPGVDLSRILNEMREQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVASNSEM--VQSSKSEISELRRTMQ---NLEIELQS
HLSMK---ASLENSLAETENRYCLQLSQIQGLVGSV-EEQLAQLRCEMGQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAQLTLH----------------------------
------KSREPVTTRQVRTI----VE------------EVQDG--RVISSREQVQ-----
----------------------------------QSNI----------------------
------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFVAGNVCVG-SGAGSSF-SCTLGGISS----
----GGSFC-NSGGG----LGSGACPGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVRA
LKEANADLEQKIKGWYEKCEP-GSFRGHNHD---YS-RYFSVIEDLKRQIISATTCNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTNGLRRVLDELTLCTTDLEIQCETLSEE
LTYLKK--NHEE----------------------EMEVLQCTAGGNVNVEMNATPGVDLT
VLLNNMRAEYEDLAEQNCKDAEA--WFNERSATLQQQISNDEGAATAARNELTELKRNLQ
TLEIELQSLMAV----KHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQK
LEYEQLLDLKIFLEKEIEIYCNLLDGEERKSKSTCYKSKGCRPVNSGNQGK-GIDGFFTW
C---NSLNSVSCVN------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVRTSGLSQRLSS---Q-G----GTLGR--
---------------ARGTSAS--SI-GSS-----YGGS----AFGFGG---S-----S-
GGGFSA-A---SM--FGSG---YGFGGGSG------------------------------
------------SSFA---GGLGAGYGGAGYGGAGYG-----------------G-----
-------------A-----------GGGDFGGLGIGF---GG----------GSP--GIL
SGNDGGLLSGSEKETMKNLNDRLASYLDKVRALEEANTDLE---NKIREWYETRGSGTGD
PRSQ-SDYSKYFPLIEELKNKIISASIANA------------QLILQIDNARL-AAEDFR
M-KY-ENEVALCQNVEADINGLRRVLDELTLVRADLETQIETLNEELAYLKKNHEE----
-V-------S-PGQVSVEMDAAPGVDLTKLLNDMRAQYEAIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRALQ---NLEIELQS
QLAMK---KSLEDSLAETEGDYCAQLSQVQQLIGGL-EEQLLQVRADAERQ--NADYQRL
LNVKARLELEIE----TYRRLLDGEAQGLRVRSLP---LLSGLTIR--------R-----
------------C-REL----WCRLQTRLGSRAGGYSSNSTPSL-GT------------S
MC----------------------------------------------------------
-----------------------------------------------------RGSG-PR
N----SNNNNNNNK-------D-----------------KKTK-----------------
---------------KKKMHFQNAKVTFKSL-NLTDCISQDLT-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGG-
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GSGGF
GGGSFR--GSYGSSSF---GG---------------------------------GYGGSF
GGGSFGGGSFGG----------GSFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGEP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--ISSYKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSFSGG-------------------
----------------YGG-----------GS---SGGGSSGGG-Y-------GGGHGGS
SGGSYGGG---SSGGGSSGGGYGGGSSSGGHGGSSGGGYGGGSSGGG---G---------
----------------------G-------------GSSGGGYGGGSSSGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MLSRQKE--NHASKQTLTHVDTPYQHIHKGL
SLSL----------V--AGAPWL--NSITMSVRYSS-SKHYSS---SRS----GGGG---
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG---------------------L---
--------GGFGGGSF---GG---SYGSS---SFGGGYG-------------G-SFG---
-GGSFGGGSFGGG-GFGG----GGF--------------------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRG-------------------GG-----
---------------SYGGG--Y----GGGSSGGGYGGGSSG-G-GYG------GGHGGS
SGGGYGG--------GSSGGGSSGGG-Y--GGGSSGGGYGGGSSGGGYGGGS--------
SS-GGHGGSSGGGHGG-S-SG----------------------GGGSSGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SGSKRSGARAST--GSLRLSSG---G-ASFGAGNACGT-PGIGSGF-SCAFGGSSS-VAN
S------------------GPSTHYAGFPLSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELEVKIKGWYEKFGP-GSCRGLDQD---YS-RYFTIIEDLKNQVIASTTSNANT
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLSETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDEGACKSGGYKSKDFGASIMGNQIK-DPIKAIVV
KKVLEEVDQRSKVLTTRLHSLEDKPQNS----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------GFRGGA-G-----S-
----------------------YGLSGGSSGG-----------------------FGGGF
GSCSVG--GGFGGASG-----SGIGFGGGSS--FGGGS----------------SFGGGS
S--FGGGSSFGGGSGFGG---SAGYAGGASGG----FYSYAGG-------VGGGVG-G--
GLGDGGLFSGGEKQAMQNLNDRLANYLDKVRALEEANADLE---NKIKEWYEKFGPRSGD
GGAG-RDYSKYYPVIEDVRTQIITATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELHLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-RGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ANSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEANYMVQLSQIQMQISSL-EEQICQIRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGG---------------------------------
---------------NM----G--------------------SR-DS------------S
M-----------------------------------------------------------
---------------------------------------------------SDGSRS-GT
S-----VQGRDP---SK----S-----------------RVTK-----------------
---------------TIVEEVVDGKVISSQVSNV----SEVKL---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSSSTTS---------
-----------------------------LSVRAPGLSRRLSS---Q-S----GMAGR--
---------------PRGMSAS--SV-GSS-----YGGC----AFGLGA---G-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSI-----------AGGLGSGYGRA-----------------------
------------------------LGGGGFGGLGMGF---GGGPG----D--ASL--GIV
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETQGTGTGD
PASQ-NDYSKYYPLIEDLRNKIISASIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALRQSVEADINGLRRVLDELTLTRSDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYEAIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGEYCGQLAQVQQLIGSL-EAQLLQVRSDAERQ--NADHQRL
LDVKARLELEIE----TYRRLLDGEAQGDGLDESL--LLVTDSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSIDSSK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGG-
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLG-F
G----G--GSYGSSSF---GG---------------------------------GYGGSF
GGGSFGG---------------GSFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSYGGG-------------------
----------------YGGG----------SSGGGYGGG------H-------GGSSGGY
GGGGYGGG---SSGGGSSGGGYGGGSSGGG------GGYGGGSSGGG---SS--------
--------------------SGG-------------GHGGGSGGGGSSGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SLVSS---S-------RAG---
----------------------GSSF-SSRSRCSLGGGS----ARGFRGGA-G-----S-
----------------------CGLSGGSSKGSGGS-------------------FGGSF
GSCSIG--GGLGGASG-----SGIGFGGGAG--FG-------------------------
---------------------------RTSGG----FYSYAGG-------MGG-------
GVGHGGLFSGGEKQTMQNLSDWLANHLDKVRALEK--ADLE---NKIKEWYDKFGPGSGV
GGAG-RDYSKYYPIIEDLRNQILTATLENA------------GIVLQIDNARL-TADDFR
L-KY-KNELHLRQPVEADINGLQKVLDDLTMTRSDLEMQTESLTEELAYLKKNHQE----
-EMKSMQRSS-GG-VTVELN--PGT--DKLLNDVRAQYEDLAEQ-NHCEAE---GQFNEQ
----------------SASLQ-AQISTDAGARPASSTKNEITELKRTLQ---ALEIELQS
QLAVK---SSLEGTLADTEAGYMVQLSQIQMQISGL-EEHICQIWSETERQ--NTEYEQL
LDIKTRLEMEID----PYHCLLDGEGGGS-GFGGS-DFRN-----S--------G-----
------------S--NT----G--------------------SR-D-------------P
V-----------------------------------------------------------
---------------------------------------------------SSDSRS-GS
C----SVQGRDPS--------T-----------------RVTK-----------------
---------------TIVAEVVDGKVVSSQVSNV----SEVKLK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ--------------------------
-------------------------------Y-------FGPGV-AFRAPSMHW------
---------------G-SS--------------GRGVSVSSARLVSRRP----G------
------------R-----------------------------------------------
------------------------------------------------------------
---VRRAAGGHEKLNMQNLNDPLASYLDKMCALEAANRELE---VKIHDWYQTQGP-R--
---PSRDYSHYYKTIQDLRDKILGATVENS------------GIVLEIDNARL-AADDFR
T-KT-ETEQALRMSMEADINGLRRVLDELTLASTDLEIQIEGLKEELAYLKKNHEE----
-KISGLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVIAVQ-NWKDAE---AWFTSR
----------------TEELN-REVAGHTDQ--LQMNRSKVADLRRTLQ---GLE--LQS
RLSMK---AALEGTL----ARFGAQLAQIQPLINCI-VAQLGDVRADSERQ--NQEYQQF
MDVKSRLEQEIS----TYRSLLEGREDHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

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----------------LSRLSS-------TSSGGGFGGN----IFGSGA---S-----S-
GGSFSA-V---SM--FGSS---CGFGNSSR------------------------------
------------SAFG---GGLGGGYGAGLG---GAG-----------------------
------------------------MGSGYGGGLGNGY---GGCP--------GSV--GIP
CSNDGGLLSGSEKETMQNLNDRLASYLAKVRALEEANTDLE---NKIRDWYETRVT--GE
PGSG-NDYEKYYPLIEDLKNKILSATIENA------------RLILQIDNARL-AADDFR
M-KY-ENEQALRQNVEADINGLGRVLDELTLPRADLEMQIESVMEELAYLKKNHEE----
-ELQAIQAAG-LGQVSVEMDAAPGINLTKFLNDIRGQYVS-AEQ-NRKEAE---AWFLEK
----------------SGELK-KEISSNTEQ--LQTSKSEITDLKRMLQ---SLEIELQS
QLAMR---KSFEDTLAETESGYCNQLSQIQLQIGNL-EAQLSQLRSELERQ--NAEYEQL
LNIKTRLEMEIE----TYRRLLEGELEGXXXXXXX---XXXXXXXX--------------
----------------------------------------XXXX-X--------------
------------------------------------------------------------
------------------------------------------------------------
-------XXXXPSR-------S-----------------RKIK-----------------
---------------TIVQEVVDGKVVNSEVREIEEEL----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-----------------------------MSVRYSS-SKQYSS---SRS----GGGG--G
-------------------GGGGSSFRISSSKGS-------------IGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG-------------------------
----LG--GGFGGGSF---GG---GYGGS---SFGGVCG-------------GGSFG---
-GGSFGGGGFGGG-GF------------------------------------GGYG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--R
QREP-RDYSKYYQTIEDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRNQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEINSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLESSLAETEGRYCVQLSQIQAQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGXXX--XXXX-X------------X-----
---------------GYGGG--SS---SGGSSAGGHGG-------GLA------GGSASS
FGGGSSG--------GGSGGCGLSGGSSSGFGGSFGGGFGSCSVGG--GLGG----T-LG
SG-ASFGGGSGFGGGS-G-FG----------------------GGSG-------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VI-GR--
---------------PRGMSAS--SV-GSG-----YGGS----ALGFGV---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGGSFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTAD
A-SQ-SDYSKYYPLIEDLRNKIISASIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHED----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---VWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAFQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
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----------------------------------------------------------MR
ETRTLQRQRPPLQETMQNLNDRLATYLDKVRALEDANSDLE---IKIKEWYKKQGPGP--
---D-RDYSPYYRTIEDLKSKILAATVDNA------------RILLQIDNARL-TADDFR
T-KY-ETELALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNILRSQL-GGEITVEMDAAPGVDLTKILADMREQYESLAEK-NRKEAE---QWFYTK
----------------TEELN-REVAMNTEQ--LQSGKSEITELRRTIQ---GLEIELQS
QLSMK---AALEGTLAETEARYGTQLAQLQALITSV-EEQLAELRCDMERQ--NHEYKIL
VDVKTRLEQEIA----TYRRLLEGEDAHIASQYAS-------------------------
------ARDASLTTRQVRTI----VE------------EVQDG--KVISSREQVH--QT-
--------------------------------VR--------------------------
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--------------------------MTTCSRQFTSS-SSMKGS----------FGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GSYGGGF----SS-SSSFGSG----FGG--------------GYG----GGL
GA----GLGGGLGAGFGG-----GLGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-S-SRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGGGLGAGF
GGGL-G-------A---------GFGGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---TWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQQ-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QSSSSFSQGQSS-
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGAGNTCGV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELIEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKN--EQRVSS---------

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-------------------------------------------------M-----SLRLS
SGSRRSSPRSGT--GSLRLSSG---G-ASFGAGNACGI-PGIGSSF-SCAFGGSSS-MGN
A------------------GTGNPCAGFAVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANTDLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRQDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLSETEGNYCSQLAQIQARIAALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDEGACKSGGYKSKDFGASNMGNQIK-DPIKAIVV
KKVLEEVDQRSKILTTRLHSLEDKPQNN----------------------

MDSSRRSFHRSLSSSSQGPALIMSSSIYRKGGLQPLVAAPSVYGGAGGHGTRISTSRQSA
SYGNDLSGGRDLFAGNEKMTMQNLNDRLASYLDKVRSLEQSNSKLEALIKQWYEANAPSG
SRDFSAYYKQMEELQNQIKDAQSQNSQRVLQIDNAKLAAEDFRLKFESERAIRLAVEADL
QGLGKVFDDLTIKRTNLEVQVEELNNDLALLKKEHQEETDALRRHLGNTVNVEVDATPGL
NLGDIMSEMRQKYEI--MAQKNLQEAKEQFERQTEALQQQVTV---D-T----Q---E--
---------------LKGTEAQVTEL-KRT-----YQSL----EIDLR------------
----SQ-L---SM--KESL-----------------------------------------
------------EHTL---EETKARYGNQLATIQ--------------------------
---------------------------GLLSSLEAQLMQVRSDTERQNNEYNALL--DIK
TRLEQ--EIATYRLLLEGED V KLASYLDKVRALEDANAELE---NKIREWYEARGHGHGD
CGPQ-HDYSKYHPLIEDLRNKIISASIGNA------------QLILQIDNARL-AADDFR
M-KF-ENEAALRQTVEADINGLRRVLDELTLARADLEAQIESLTEELAYMKKNHEE----
-ELQSCRAGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYEAIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRALQ---NLEIELQS
QLAMK---KSLEDSLAETEGDYCGQLSQVQQLVGDL-EAQLQQVRSDTERQ--NMDYQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLDESS---AMTGSRSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPSK-------T-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVQEIQELM----------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------------MTSCSYPQ----SSSTS----------SFGGL--
-G-------------------------GGSVH-------FGPGV-AFRAPSIHA------
---------------G-SG--------------GRGVSLSSARFVYSSS----S------
------------GG----------------------------------------------
-----------CGGGYGC-----I------------------------------------
LAASNGLLAGNEKLNMQNLNDRLACYLDKVRVLEAANRELE---VKIRDWYHKQGP-G--
---PSRDYSHYYKTIQDLRDKILGATIDNS------------R I----------------
---F -ETEQSLCMSLEADINGLHRVLDELTLARTDLEMQIEGLKEELAYLKKSHEE----
-ELSVLRGQA-GGQVSVDMGSAPGTDLAKILSDIQSQYEVMAEQ-NRKDAE---AWFISR
----------------TEELN-REVAGHREQ--LQKSNTEVSDLRRTLQ---GLEIELQS
QLNMK---AVLEGTLAETEARFGAELAEIQARISGI-EAQLGDMRANSEQQ--NQEYQRL
LDVKSRLEQEIA----TYRSLLEDQENRY-NNLSASKVL---------------------
------------------------------------------------------------
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---------------------------MSRS-------ACVSS---S-------RAGGGS
---------------SARVSAAGSSF-SGGSRCGLGGSS----ARGFRGGT-G-----G-
----------------------CGLSGGSSSAFRGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSS---GG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEELRNQNIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQVSAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEEGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSV----SEVQV---------K-------
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--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------------SSR------------------ASCRLS-----
---------------GSLGG----------GSCRL-------GSA-----SGLG------
--------SS-----LGGGSSYSSCYSFGSGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVEGLLAGGEKATMQNLNDRLASYLDKVRALEQANAELE---VKIRDWYQRQAPGP--
---V-RDYGPYYKAIEDLKSKILVASVENA------------NVLLQIDNARL-AADDFH
T-KF-ETEQALRMSVEADINGLRRVLDELTLARGDLEMQIENLTEELAYLKRNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQY---------------------------K
-------PKEPVTTRQVRTI----VE------------EVQDG--KVISSHEQVH-----
----------------------------------QTTR----------------------
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-----------------------------MSVRYSS-SKHYSS---SRS----GGGGG-G
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSS-G---SF--SRGSSGGGCFGGSSG-GYGG---------------------L---
--------GGFGGGSF---GG---GYGSS---SFGGGYG-------------G-SFG---
-GGSFGGGSFGGG-SFGG----GGF--------------------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRG-------------------GG-----
---------------SYGGG--Y----GGGSSGGGYGGGSSG-G-GYG------GGHGGS
SGGGYGG--------GSSGGGSSGGG-Y--GGGSSSGGYGGGSSGGGHGGSS--------
GG---------GGSSG-G-GF----------------------GGGSSGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
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-------------------------------------------------M-----SFRLS
SGSRWICSQA----GSGRLSGG---G-TGFGAGNTCGG-LGAGGSF-PGALGSASS----
----VGAFS-SSGGG----LGSGVCAGFLGNEHGLLSGNGKVTMQNLNDRLASYLDHVRA
LEEVNADLEQKINGWHEEYGP-GSRRELAHD---HS-RYLSVVEDLKRQIISVTACNASV
VLQNDNARLTT-DDFRLKYENELALHQSVEADINSLHRVMDELTLCTTDLEIQCEALSDE
LTYLKK--SHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNHMRAGYEDLAEQNRRDAEA--WFNEKSTSLQQQIYDDAGAATAARNELTELKRSLQ
TLEIELQSLMAK----KHSYEGSLAETEGSYCLQLQQIQDQVGMMEGQLQQTRTETEGQK
LQYEQLLDIKIFLEKEIETYCKLIDGEERKSKSTCYKTKGRGPINSENQIK-DSKEETVV
KTVVEELDQLSKVLSLRVHSFEEKSSKISNITV--EQRVPSKAPK-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVRTSGLSRRLSS---Q-S----GMSGR--
---------------PRGISAS--SI-ASGYGGSGYGGS----GYGLGM---G-----Y-
GGGFSA-A---SM--FGSS---SVLGGGSG------------------------------
------------SSLA---GGLGAGYGGSLGGGFGGG-----------------------
------------------------MGMGMGMGMGMGM---GGNLG----G--GSL--VVL
SGNDGGLLSGSEKETMKNLNDRLASYLDKVRALEEANADLE---SKIRDWYETRGTRTVD
SGSQ-NDYSKFYPVIEDLRNKIISANIGNA------------QIILQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRKVLDDLTLARTDLEMQIENLTEELAYLKKNHEE----
-ELLSFRAGG-PGEVSVEMDAVPGVDLTRLLNDMRTQYESMAEQ-NRKDAE---AWFLEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAMQ---NLEIELQS
QLAMK---KSLEDSLAETEGGFCYQLSQVQQLIGNL-EAQLQQVRADAERQ--SVDHQRL
LDAKARLELEIE----TYRRLLDGEDQGCVHVQTG--NTFRG------------------
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-------------------------------------------------M-----SLRLS
SGSRRSCPRPTA--GSLRLSGV---T-AGFGAGNTCSM-SGIGSSF-SCTFGGS-SSGGN
V------------------GGSNLCAGFTLNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGNQVK-DLAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQNKYSQRR--ESIMS----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGAGFGGGL
GGGL-G-------G---------GFGGV------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPVLQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQS-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QGSSSFSQGQSS-
------S-----------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
----------------------MSC-RLQTSS-------SSYGA-GYGGGSCQL------
-----------------GG--------------GRSFSTCSTRFASGGSAGGYG------
------------AG------M-SCGFGAGAGSGFGGGY----------------------
----GGGFGGSFGG---------GFG--------------------------------DF
GGGDRGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQSPVS--
---PERDYSRYYKDIEELRAKILAATTENN------------QVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLRKNHEE----
-EMKEFSKQV-VGQVNVEMDATPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFQSK
----------------SAELN-KEVASNTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLEGTLAETECRYALQLQQIQGLISGI-EAQLADLRAETECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDA---------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLA------
------------S-ALGS-NSYSSCYSFGTGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSSYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNSLRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL-S---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
--------------------------MASYSYRQ----SSSAL----------FFGDM--
-G-------------------------SGSML-------FRLVA--TSAPSIHG------
---------------G-SG--------------GRGVSMSSARFVSSSSSGG--------
------------------------------------------------------------
-----------YGNGYAG-----VLS----------------------------------
--TSDGLLSGNEKITMQNLNDRLASYLDKVCALETANTDLE---VKIRDWYQKQGP-G--
---PASDYNHYYKTIEDLRDQILGATIQNS------------KVVLQIDNARL-AADDFC
I-KF-EAEQAL-VSVEADINRLRRVLDELTMAPADLEMQSEGLKEELAFLKKN-------
-----LKAQV-GGQVSVEGDSTPGIDLAKILNHMRSQYELMAEK-NRKDAE---AWFIKQ
----------------TEELK-LEVDVHTEK--PRVSNTEVTDLRQMLQ---SHEIELQS
QLSMK---AALEGTLAETEARLGAHLAQIQAMVSSM-EAQLSEVRSNTEWQ--NQEYQLL
LGIKSRLEQEIA----TYRSLLEGQDAHY-KDLATTRA---L------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------MSLRISTA-------SRRIS---P-------IAGGNG
---------------GIKL-------------LGSGGSG----MHGYGGGSLA-----A-
------------------------LG----SGCGGS-------------------VCGGF
GG------AGFGSGGG---YGSGVSFS-SRGSGFGGGS----------------GFGGGS
G--------FGGGSGFGG---EAGFGSASMSS-----ANYGGNYR--PSSAMVSSS-G-F
GTGDSIFLAGAEKETMQNLNNRLANYLEKVRSLEEANAELE---VKIRHWYEKNGPG--A
PGVV-RDYTKYHQIIEDLRNKIVNTTIDNA------------NVVLQIDNARL-AADDFR
L-KF-ENELFLRQSVESDINGLRRVLDELTMNRSDLEAQLENLTEELAYLKKNHEE----
-EINMLKSNS-TGDVTVEMNAAPGIDLTKLLNDMRAQYEDLAEQ-NRREAE---EQFHKM
----------------SQPLQ-QQIYDDAGA--VSSARNELIELKRSFQ---SLEIELQS
LLAKK---ASLEGTLTETEANYSSQLHQLQLQVSNL-EEQLQQIRSETECQ--NSEYQQL
LGIKTRLEMEIE----TYRRLLDGENFHSY--------D---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
T----KVHMREPSK-------T-----------------RVVK-----------------
---------------TIVEEVVDGKVVSSQVKSV----EERATK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NVCRSTMSCS-------SRVSS---S-------RAGGSG
---------------SVRVSAAGSSF-SSGSRCGLGGGS----TRGFRGGT-G-----G-
----------------------CGLSRGSSSGSGGG-------------------FGS--
---SVQ--GGFGGTSG-----SGAGFGGGSG--FGGGS----------------G-----
---------FGGGSGFGG---GSGIGGGASGG----FYIYGGG-------LGGGRG-G--
GVGDGGLFSGGEKQTMQNLNDRLASYLDKVRALEEANSDLE---NKIKEWYDKFGPGSGD
GGSG-KDCNKYYPVIEDLRNQIIAATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLWQAVEADINGLRKVLDDLTMTRSDLEMQTESLTEELAYLKKNHEE----
-EMKTMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELRRTLQ---ALEIELQS
QTAMK---SSLEATLADTEADYMAQLSENQMQISGL-EEQICQIRGETECQ--NAEYEQL
LNVKTCLEMEIE----TYHRLLDGEGGNT-------GSR---------------------
---------------NM----G--------------------SR-DL------------S
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGREA---NK----T-----------------RVTK-----------------
---------------TIVEEVVDGKVISSQVSNV----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSVRYSS-SKQYSS---SRS----GGGG--G
-------------------GGGGSSFRISSSKGS-------------IGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG---------------------LG--
-GGFGG--GGFGGGGF---GG---GYGSS---SFGGGYG-------------GGSFG---
-GGSFGGGGFSGG-SF------------------------------------GGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGGS--G
QREP-RDYSKYYQTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVTLRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRNQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEINSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCMQLSQIQAQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGRIIPIGLIRCSKSP-GFS----K-TQSAG-----
---------------GWAKG--RR---RGKA--------------EYR------ESCVHI
--KLFVS--------G-------SENPYSTVVASHGGGYGGGSSGGGG------------
----GHGGSS---SGG-G-YG------------------------GGSSGGHKSSSS-GS
VGE---PSSKGPRSAETSWGNQ-----------------N--------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGRLCG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSVFGG-------------G-VG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTIEELRDKIRATTIDNS------------RVILEIDNARL-AADDFR
L-K--------------------CVLDELTLARTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGIREASS---GGGSS------------
-------------SSNFRINIE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVRTSGLSRRPSS---Q-S----GTSGR--
---------------ARGTSAS--IV-GSG-----YGGS----TFGFGD---S-----Y-
GGGFSS-A---SM--FGSS---SGFGGGSG------------------------------
------------ISFA---GGLGSAYGGALGGGSGAL-----------------G-----
-------------GGFGSLGSGFGGLGGGFGGLGIGF---GGSPG----G--GPG--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGSGTGD
PGSQ-SDYSKYYPLIEDLRNKIISATIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALRVSVEADTNGLRRVLDELTLARADLEMQIENLREELAYLKKNHEE----
-ELQTFLAGG-PGQVSVEMDAAPGLDLTRLLNDMRAQYEAIAEQ-NRKDAE---AWFVEK
----------------SGELR-KEISINTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLATK---KSLEDSLAEVEGDYCGQLSQVQQLIGSL-EEQLLQVRADAERQ--NADHQRL
LNAKARLELEIE----TYRRLLDGEAQGDGFDESL---YVTDSKSQ--------------
----------------------------------------TQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------S-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVQEELI------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSSAS----------TFGGL--
-G-------------------------GGPAR-------FGGGS-SFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS--S----------
------------------------------------------------------------
------------SGGYGG-----GYGV----S--------------------------L-
-AGSDGLLSGNEKITMQNLNDRLASYLEKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYFKTIEDLRDKIHGATIDNS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLKGQV-GGQVSVEVDSAPGVDLAKILSEMRSQYEVMAEK-NRKDAE---AWFVSR
----------------TEELN-QEVAINTEQ--LKTSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISSI-EAQLSDVRADTERQ--NQEYQQL
MGIKSRLEQEIA----TYRSLLEGQDIHN--NLPTPKV---V------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVRTSGLPQWLSS---Q-S----GTLGR--
---------------ARDMSAS--SI-GSG-----YGGS----AFGFGG---N-----S-
GGGFSA-A---SM--FGSS---SGF------GSSSG-------------------FG---
-----------GGSFA---GGLGAGYGGAG------------------------------
--------------------------GGGFGGLGIGF---GGSSG----G--GSV--GIF
PGIDGGLISGSEKETMKNLNDRLASYLDKVRALEEANTDLE---TKIREWYETRGSGTGD
PGSQ-NDYSKYYPLIEDLRNKIISANIANA------------QLILQIDNARL-AADDFR
M-KY-ENELALCQSVEADINGLRRVLDELTLARADLETQIETLNEELAYLKKNHEE----
-ELQSCRAGG-PGQVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWLAAI
H--------------GSGELR-KEISSNTEQ--LQSSKSEVTDLRRALQ---NLEIELQS
QLAMK---KSLEDSLAETEGDYCGQLSQVQQLIGSL-EEQLLQVRADAERQ--SADYQRL
LNVKARLELEIE----TYRRLLDGDAQGDSLVESS---YVTASTSQ--------------
----------------------------------------APST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------A-----------------RKIK-----------------
---------------TIVQEVVNGEVVSTQVKEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
GGSRHTC-LRP-GTGSVRSPSG---G-AGFAGSNAGGG-SAAGSGFL-SAIGSGFSAGGY
GGG----------LG----GGSASCVAYTGSENGLLSGNGKVTMQNLNDRLASYLDKVRA
LEEANAELEQKIKAWYEQYGP-GSCRGLDHD---YS-RYFSIIEDLGNQIISATASNANV
LLQNDNARLTA-DDFRLKYENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
LMLNNMRAEYEALAENNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAHIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEEGSCSKA----K--GYREPGTQIK-DSLISSIV
KTVVEEIDPRGKVLSSRVHTVEEKSAKAS-NKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSTRFVSGGSAGGYG------
------------GG------V-SCGFGGGAGSGFGGGYGG--------------------
--GYGGGLGGGFGGGFAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANANLE---VKIRDWHLKQSPAS--
---PERDYSPYHKTIDELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAR
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGVPSSAGSVSPRSTSVTTT----------
-------S------SAS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-----------------------------MSVRYSL--KQYSS---SRS----GGGGG-G
-------------------GGGASAHRISSSKGS-------------LGGGFR-----L-
GGGFGG-S---SY--GGGSYGGGSFGGAYA------------------------------
-GGSCG--GGFG----------------------------------------GGSYG---
-GGGFGGGSFGGG-SYGG----GSFGGGSFGG--GGY--------------GGGFG-GGY
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---SKIKEWYEKHSNV--G
RGEP-RDYSKYYDTIDDLKNKILKQTTDNA------------NTLLQIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKSDLEMQIESLTEELQYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKDLT-TEIDTNIEQ--MSSYKSEITELRRNVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCMQLSQIQTQISAL-EEQLQQIRAETECQ--NSEYQEL
LDIKIRLENEIQ----TYRSLLEGEGSGRGGGRGGGSSSG--------------------
---------------G-----------HGGSSGGGYGGSSGG---GYG------------
------G----------SSGGSHGGSSGGGHGGSSGGGYGGGQG----------------
---GSSGGSHGGSYGG-GSSG---------------------GGGQSGSGGFKGPSS-GS
PGE---S-SKGPRSGDTSSGDQ-----------------RQLA-----------------
---------F----SPPCACFLNYRAA---------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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---------------------------MSCSIKRTSS-TSYR----SGAGA---------
--GGACGGS--------------SG-RSSSVSCRRYAS-------------S--------
-----------VIGG-------------------------------------------GY
G--------------------------GA----ACGGYGG---G----------------
----LSMGGLAGGFG--G-----GFA---------------------------GSC--G-
-PGGDLLLSGNEKVTMQNLNDRLAAYLEKVRRLEEENAQLE---HHIREWYRKQAPSV--
---S-KDYSSYYQTIEQLQNQIISATVDNN------------RMLLDIDNSKM-TADDFR
M-KY-ENELVIRQTVEADINGLRNILDGLTTTRSSLESELESLKDELIALKRNHEE----
-EMRQLQSQT-GGDVSVEVNAAPGEDLTKILNDLRDEYEQIIEK-NRREVE---QWYEVK
----------------IQEVN-QQVTSSSQD--IQTSSHQLSELRREMQ---NLEIELQA
QLSTK---SSLENSLAETESRYGRMLQQIQAQVNSV-EEELGSIRCEMEGQ--SQEYKML
LGIKMRLEQEIQ----QYRALLQEGQQDLVSSQG--------------------------
----------------------------AL-Q---------G--------------GG--
--------------------T-SSH-------S---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------Y----------------------------SSS--S-YCH
GQSS-D------------------------------------------------------
---------------------------K--------------------------------
------A--GQS--------------------RVC-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQSSS-------ASYGG-GFGSGSCQL------
-----------------GG--------------GRSFSTCSSRFASGGSAGGYG------
------------GG------M-SCGFGGGAGSSFGG------------------------
--------------GFGG-----CFG--------------------------------DF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQRQSPAS--
---PERDYSRYYTTIGELQVKILAATTDNN------------RIVLEIDNARL-AADDFR
L-KY-ENELSLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSKQV-VGQVNVEMDATPGVDLTRVLAEMREQYEVMAEK-NRRDAE---AWFQSK
----------------SAELN-KEVASNTEM--IQSSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYALQLQQIQGLISSI-EEQLAQLRSEMESQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDARL-TVSASPTGSVSYSSTSASSS----------
-------G----FHLGLRFRLR--------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------SAYGG---------------LSV-TSSRFSSGGA-CGIG------
--------GGYGGGF----SSSSSSFGVGLGSGFGG---------------------AGF
GGGFGG-------AGFGS-----GFGGG------------------------------F-
GG--DGLLVGSEKVTMQNLNDRLATYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---I-KDYSPYFRTIEELKSKIIAATLENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLISNV-EEQLAQLRCEMEQQ--SQEYNIL
LDVKTRLEQEIA----TYRRLLDGEDAHISSSQH-SSGQSYSSHEGKA--SGVPE-----
----------------TMSHS---LT------------LWAVG--QAPRCR---------
------------------------------VLGFPSPTWQLA------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVCTSALSRRSSS---Q-N----GAAGR--
---------------PWGASAS--SV-AGG-----YGGS----ASGFGV---G-----C-
GGLFSA-A---SM--FGSS---SGFSGGSA------------------------------
-------------GCL---PGLGSAYGGPLRGGAGGM-----------------------
-------------------------------GIGMGI---AGSSG----G--GSL--CIF
SGNDGGLLSGSEKETMQNLNDRLASYLGKVRSLEEANAELE---NKIREWYETRRT--RD
AGSQ-SDYSKYYPLIEDLKNKIVSARVSNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRRVLDELTLTRADLEAQLETLTEELAYMKKNHEE----
-ELQSFQAGG-PGEVNVEMDAAPGVDLTKVLNEMRAQYEAMAEQ-NRKDAE---AWFLEK
----------------SRELR-KEISSNTEQ--LQSSKSEVTDLKRMVQ---NLEIELQS
QLAMK---SSLEGSLAETEGGYCCQLSQVQQLIGSL-EEQLQQVRADAERQ--NADHQRL
LGVKARLEMEIE----TYRRLLEGDSQGDGFDESS---SLSVSKP---------------
---------------------------------------QTPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVQELEEEM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-T--S---S----------TFGGG--
ST------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGYG------
------------GG------M-SCGFGGG----------------------AG-------
-SGFGGA----FGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PERDYSHYFKTMEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARTDLEMQIEHLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQSSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGLISSL-ESQLSELRCEMEAQ--NQEYNML
LDIKTRLEQEIA----TYRNLLEGQDAKM-AGIGVREASL---GGGSGGG----------
-----------SSSSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LPGNSVL---------
-----------------------------LSVRTSGPSRRLSA---Q-S----GIVGR--
---------------PRGMSAS--SV-GNG-----YGGN----AFGFGA---G-----Y-
GGGFSA-A---SM--FGSS---SGFGGGCG------------------------------
------------SSLA---GGLGSSLAGGLGSGYGRA-----------------------
------------------------LGGGGFGGLGIGF---GGSSG----S--ASL--GLI
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
PASQ-SDYSKYYPLIEDLRNKIISANIGNA------------QILLQIDNARL-AAEDFR
M-KY-ENELALRQSVEADINGLRRVLDELTLARSDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYEAIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGEYCGQLSQVQQLIGNL-EAQLLQVRADAERQ--NSDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVPDSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------K-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEEPM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQFSS---SRS----GGGG---
----------------------GGSCRISSSRGS-------------LGGGFS-----S-
-GGFSG-S---SF--SRGSSGGGCFGGSGG--YGG------------------------L
GGGFGG--GGFGGGSF---GG----------GSFGGGYG-------------SSSFSGGF
GGGSFGGGSFGGG---------------SFG---GGY--------------GGGF-----
GG-DGGLLSGNEKVTMQHLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--N
QGQP-RDYSKYYQTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
M-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEEVAYLKKNHEE----
-EMKNLGNVS-TGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--MSSHKSEITELRRNVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISSL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGRITPMTFISVFYIG--------RK--PQG-----
------------NAREWEETDTNKTRVIKT-----IIEEVAPDG-RVLSSMVESETKKHY
Y-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
GGSRRICLPAG--TGSVRPASG---G-TGFAGSNACGT-SVPGSGF-SCTLGGGLG----
----GVPSGRHTSGA----LGNAACVGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKVISSTAANANV
ILQIDNARLAA-DDFRLKYENELALHQNVEADINGLRRVLDELTLCRTDQELQFESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEN--WFNEKSATLQQQISDDAGAATSARNELTEMKRTLQ
TLEIELQSLLAT----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEHEQLLSIKVHLEKEIETYCRLIDSDGNSCS----KSKGFESGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNSKT--EPRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSL-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSVGGYG------
------------GG------I-SCGFGGGAGSAFGGGYG---------------------
-----GGLGGGFGGGFAG-----GFG--------------------------------DF
CAGDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANTDLE---VKIRDWHLKQSPSS--
---PERDYSAYYKTIEELREKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELSLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHAK
----------------SAELT-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENSVAETECRYALQLQQIQGLISSI-EAQLSQLRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSAGNVSPRSTSVTTTA----------
-------S------AS-----V----------------TT-------T-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLQFS
NGSRHVCLRSG--AGSVRPLNG---G-AGFAGSGACGG-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLA
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDSGAATSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLECSLTETESNYCTQLAQIQAQIRALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSPGNSSK-DLSKTTLV
KTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRACPRPT--TGSLRLSG----GGASFAAGNACSI-SGIGSGF-SCAFGGSAS----
----GGNAG-----------GSNSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANT
VLQIDNAKLTA-DDFRLKYENELALHQSVETDVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXGDDGACKSGGYKSKDYGSGNMGNQVK-DPAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKAQNN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------FGGGF
SSISGM--GGHGGDWG-----SGAG-----------------------------------
----------------------------FGGG----FSSYCAGAL-----GSGGTG-S-L
GASDGGLFSGSEKQTMQSLNDRLASYLDKVHALEEANTDLE---VKIKEWYDKSG--NKD
ADSK-KDYNKYYQIIEGLRNQIIEATIDNA------------KIMTPIDNARL-AAEDFR
M-KY-DNELCLRQSVEADINGLHKVLEELNMTTSGLKMQFESLNEELVYLKKNHEE----
-EMNSTQGKN-HGDVSVEMNAAPGMDLTKMLNNMRAQYEELAEQ-NRREAE---DQFQKQ
----------------SSALQ-AQIITDTGA--TDSAKSEMMELKRTLQ---GLEIELQS
LMAMQ---DSLEGTLADTEADYVARLSQMQLQISSL-EQQICQIRGEMECQ--NTEYEQL
LNIKTRLEMEIE----TYRSLLDGE-----------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLGSCGG--VGSVRMSSG---G-AGFGAGNTCGV-SGFGSGF-SCAFGGSSSAGGY
GAG----------LG----GGSASCAAFIGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANTDLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIISATTSNASV
ILQNDNARLTA-DDFRLKFENEQALHQSVDADVSSLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------DMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFHEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLSETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCVKS----K--GYKGPGNQIK-DSSKTTTV
KTIIEEIDPRGKVLSSKVHTTEEKPTKVNNMKS--EQKVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSHS-------TRVSS---S-------RAGGSS
---------------SARVSGGGSSF-SGGSRCGLGGSS----ARGFRGGA-G-----S-
----------------------CGLSGGSSSAFGGS-------------------FGGGF
GSCSVG--GGLGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSS---GG----FYSYGGG-------M----R-G--
DVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDDSKYYSIIEELRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADISGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYDELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQISAL-EEEICHLRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRHLLDGEGGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISTLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISSI-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------TTTVRQYSTS-GSMKG--------LCT-G----
----G-----------------GSS-RVSSVR--------------VGGA-CLAP-----
---------------SLLGA----------GSCGNMSA-TSSRFT-----SSLG------
--------GSYG-------GGYGGGYSCSLGGGFGT------------------------
---------------------------S------------------------------YG
--VGDALLGGSEKETMQNLNDRLANYLDKVRALEEANTDLE---LKIRDWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SLVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNTEA--LQSSKTEITELRRTVQ---NLEIELQS
QLSMK---ASLEGTVAETEARYGAQLTQLQGLISSI-EQQLCELRCDMERQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAXXXXXXXX-X--------------------XXX
X-----XXXXIVTSRQVRTI----ME------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------MATTTSIRQFSTS-GSIKG--------LCAPG----
----G-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SFLGS----------GSCGNMSV-TSSRFS-----AGLG------
--------GSYG-------G---SGYTCNLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGSEKETMQNLNDRLAAYLDKVRALEEANADLE---VKIRDWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SFVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLSRADLEMQIETLKEELAYMKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLGQLQGLICSV-EEQLAQLRCDMERQ--SHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-M-------------------ASQ
S-----SREAMVTSRQVRTI----VE------------EVQDG--KMVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRNISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSAFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTTEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGGS------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------------SSR------------------TSCRLS-----
---------------SGLGA----------GSCRL-------GSA-----SGLG------
--------SSLGSA-L-GSGSYSSCYSFGSGSG---------------------------
---------------YGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSHYYHTIEDLKNKILTATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMNSLRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEE-GPGEV-----RKADK
----------------TEELN-REVATNTEL--VQSSKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCDMEQQ--NQEYKIL
LDVKTRLEQEIT----TYRRLLEGEDAHLTQY----------------------------
------KPKEPVTTRQVRTI----VE------------EVQDG--KVISSREQIH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-----------------------------MSVRYSS-TKQYSS---SRS----GGGG---
-------------------GGGGSSLRISNSKGS-------------LGGGYS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GFGG---------------------IG--
-G-------GYGGGSF---GG---GFGGS---SFGGGYG-------------SGGYG---
-GGSFGGGSF------GG----GSFGG-------GGY--------------GGGFG-GGF
GGD--GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYQTIEELKNQILNLTTDNA------------NVLLQIDNARL-AADDFR
M-KY-ENEVTLRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELQYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEK-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQGQITSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGSYGGGRGGG-S----------SGG-----
---------------GYGGS----------SGGGSYGGSSGG-G-GYG------GSSGGS
----------------------HGGSSGGGHGGSHGGSFGGGSSGGGGHGSS----S---
------GGGHGGSFGG-GSSG----------------------GGQSGSGGFKSSSS-GS
AGE---ASSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LPSNSVS---------
-----------------------------LSVRSSGLSRRLSS---Q-S----GIAGR--
---------------PRVMSAS--SA-GSG-----YGGS----TFGFGA---S-----H-
GGGFSA-A---SM--FGSG---AGFGGGSG------------------------------
------------SSW-----------AGGLGTGYGRA-----------------------
------------------------MGGGGFGGLGIGF---GGSAG----N--ASV--GII
SGNDGGLLTGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
PASQ-SDYSKYYPVIEDLRNKIISANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRRVLDELTLAKADLEMQIENLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGEYCGQLSQLQQLIGSL-EAQLLQVRADAERQ--NADHQRL
LDVKARLELEIE----TYRRLLDGEAQGDGLDESL--LFVTDSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------K-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRHFSS--GSIKG--------SSGLG----
----G-----------------------ISS------------------RSCRVS-----
---------------GSLGG----------GSCRL-------GSA-----GGLG------
--------SGLG------GSSYSSCYSFGSGGGYGS--------------G--GF----V
GG------------GFGG-----GFG----------------------------------
--GVDGLLVGGEKATMQNLNDRLASYLDKVRALEEANTELE---LKIRDWYQKQAPGP--
---A-PDYSSYFKTIEDLRNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADTNGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMKALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTLQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLVSSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHWLCSGGWG----------------------WA
P-----THPGSVTTRQVRTI----VE------------EVQDG--RVISSREQVH-----
----------------------------------QTTH----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRVSS---S-------RAGGSS
---------------SARVSAGGSSF-SSGSRCGLGGSS----AQGFRGGA-S-----S-
----------------------CSLSGGSSGAFGGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGTGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSRFSSGASGG----FYSYGGG-------M----G-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGLG-RDYSKYYSIIEDLRNQIIAATVENA------------GIILHIDNARL-AADDFR
L-KY-ENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLKKNHEE----
-EMKNMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ATSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQISAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEVEIE----TYRRLLDGEGGGS-------SFAEFGGRNS--------G-----
------------S-INM----G--------------------SR-D-------------L
A-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIVEELVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGS---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-NDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYG---------------GLSV-STSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSYG----GGFGG--------------GYGGGLGAGF
GGGL-G-------AGFGG-----GLGGG------------------------------F-
GGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQS-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---TWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLISSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-TSGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QSSSSFSQGQSS-
------KN----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------IIAATIENA------------GVVLQIDNARL-AADDFR
L-KY-ENELYLRQSVETDTNGLRKVLDDLTMNRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKTEITELKRTLQ---GLEIELQS
QLAMK---NSLEGTLADTEADYVAQLSQLQMQISSL-EQQICEIRGEMECQ--NSEYEQL
LNIKTRLEMEIE----TYRRLLDGEGGSSSIG-GSGGSGGSNSW----------------
---------------KS----G--------------------NR-GS------------T
S-----------------------------------------------------------
---------------------------------------------------HDDSRG-GN
S----SGQGKDSNK-------T-----------------RVTK-----------------
---------------TIVEEVVNGKVVSSQVSNV----SEVKVK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGG-
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GL-GF
GGGSFG--GSYGSSSF---GG---------------------------------GYGGSF
GGGSFGGGSFG------G----GSFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTDYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSYGGG-------------------
----------------YGGG----------SSGGGYGGGSSGGG-Y-------GGGHSGS
SGGGYGGG---SSGGGSSGGGYGGGSSGGGHGGSS---------GG--------------
-------------GHG-GSSGGG-------------GSSGGGFGGGSSGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
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-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSARLSGG---G-TGFVAGNACVG-SGAGSSF-SCTLGGISS----
----AGSFC-NSGGG----LGSGACAGFLGIEHSLLSGNEKVTMQNLNDRLASYLDHVRA
LEEANADLEQKINGWYQKCEP-GSSRRHDHD---HS-RYFSVIEDLERQIISATTCNTSI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTNGLRRVLDELTLCTTDLEIQCETLSEE
LTYLKK--NHEE----------------------EMTVLQCTAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--WFNERSATLQQQISDHEGAATAARNELTELKRNLQ
TLEIELQSLMAM----KYSYECSLAETEGNYCNQLQQIQDQIGAMEEQLQQIRTETEGQK
LEYEQLLDVKIFLEKEIEIYCNLLDGEERKGKSTCYTSKGYEPVNSRNQAK-DSTEETIV
KTVVEELNQIGNVLSLRVHSVEEKSSKISNITM--EQRVPSKVP------

------------------------------------------------------------
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----DLLLSTNEKLTMQNLNDRLASYMDKVRLEEE-NSQ-L---SSIREWYKSQAPSQ--
---S-KDYSQYYRTIEELQNQIVGANVDLN------------RMLLDMDNTRM-TVDDFR
L-KY-ETEYTLHQSVASDINGLRPLLDQLTLSRSDLETQFESLKEELIFLKKNHEE----
-EMRGLQGQS-GGDVNVEVNATPGINLMEKLNEMRCEYERLIEN-NRKEVE---SWYETK
----------------MEEVN-QQVHTSGQE--IQSSNQQISELRREYQ---SLEIELQS
QISM--------------------------------------------------------
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---------------------V----------------------LSSNTMS---------
-----------------------------LSVRPSELPQRLSS---Q-M----EASSR--
---------------ARGMSAS--SV-GSG-----CGGS----ALGFGG---N-----C-
GGGFSA-A---SM--FGSS---SGFGGASG------------------------------
------------SSL-----------IGGLSTAYGGA-----------------------
------------------------LG-GGFGGLGIGL---GGSPG----S--CSL--GIL
SGSDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYEARGSGTGD
PELQ-NDYSKYYPLIEELRNKIISATIGNA------------QIILQIDNARL-AAEDFR
M-KY-ENELALHQSVEADINGLRRVLDELTLARANLEMQIESLNEELAYMKKNHEE----
-ELQSFQAGG-PGQVSVEMDATPGVDLTKLLNEMRAQYETMAAQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKNEITDLRRAFQ---NLEIELQS
QLAMK---HALEGSLAEAEGDYCQ-LLQVRQLISSL-EEQLLQVRSDTERQ--YADHQRL
LNAKARLELEIE----TYRQLLDGDVQSGGIDESS---SMAGSRSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEVVNGEVVSSQVQEIEELI----------------------
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-------------------------------------------------M-----SLRFS
GGSRHVGLQS----GSLRPSGA---G-AGFGGSSAGGS-SAAGSGF-SWSLGGTLS----
----GAPGGSHPTGA----LGNAAGVGFVGNEGGLLSGNEKVTMQNLNNRLASYLDNVKA
LEEANAELERQIKNWHEKYGP-GSCRGLDHD---YS-QYHLTIEDLKSKIISSTAANANI
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
LTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPSVDLT
VLLNNMRAEYEALAEQNRRDAEA--GFQEKSATLQQQISNDMGAVTSARTELTELKRSLQ
TLEIELQSLSAT----KHSLECSLAETEGNYCSQLAHIQAQIGALEEQLHQVRTETEGQK
LEHEQLMDIKAHLEKEIETYCRLIDGDENSCS----NSKVFESGSSGNSSK-ELSKTTLV
KAVVEEIDQRGKVLSSRIHSIEEKMSKTSPGKA--EQRAPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLCG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSVFGG-------------G-FG-------
-GGVGGGFGGG------------------------------------------------F
GGGNGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIHDWYQKQTPTS--
---PECDYSQYFKTIEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGIREASS---GGGGS------------
-------------SSNFHINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
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--------------------------------------------------

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--------------------------MATCSRQFTSS-SSMKG--------SCGISGGS-
------------------------S-RMSSIL---------------AGGSCRAP-----
---------------STCG---------------GMSV-TSSRFSSGGA-CGIG------
--------GGYGGSF------SSS--------------------------SFGGGLGSGF
GGGFGGGLGGGLGGGLGG--------GI---------------------------G----
----DGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLE---VKIRDWYQRQRPTE--
---I-KDYNPYFKTIEDLKSKIIIATQENA------------QFTLQIDNARL-AADDFR
T-KY-ENELFLRQSVENDINGLRKVLDELTLSRADLEMQIENLREELAFLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDVE---AWFLRK
----------------TEELN-KEVASNSDL--IQSNRSEVAELRRVFQ---GLEIELQS
QLSML---TALLWTVVFFSRSLLLIL----------------------------------
------------------------------------------------------------
----------------PPAP----VH------------P--QG---ARFNQLQPEPKSE-
----------FQG-----------------------------------------------
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--------------------------------------------------

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--------------------------MTTTIHQFTSS-SSIKG--------SPGLG----
----G-----------------G-----LSH------------------TSCWLS-----
---------------GGLGA----------SSCRL-------GCA-----GGLG------
--------SAPG------GSSYSSCYSFGSGGG---------------------------
---------------YGS-----SFG----------------------------------
--GVDGLPAGGEKATMRNLNDRLASYLDKVRALEEANTELE---VKIHDWYQRQAVGP--
---A-HDYSQYYRTIEELQNKILTATVDNA------------NILLQIDNAHL-AVDDFA
PSEF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLREELAYLKENHE-----
-KVRWLGQKV-GGEISVEMDAAPGVDLSHILNEMRDQYEKMAEK-NRKDAK---DWFFSK
----------------TEELN-REVATNSEL--VQSSKSEISELQGTTQ---ALEIELQS
QLSMK---AYLEGNLEETENRYRVQLSRIQGLIGSM-EEQVAQLRCEMEQQ--NQEYKIL
LD------QEIA----TYRRLLEGKDAHLTQY----------------------------
-------KKESVTTRQVRTI----VE------------EVQDG--KVISSPQAEG--G--
---------------------------------HQTCRRGEDP-----------------
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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGAATSARSQLTELRRTLQ
TLEIQLQSLMAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYG---------------GLSV-SSSRFSSGGA-CGIG------
--------SSYGGGF----SSS-S-FGGGYGAGLGG--------------GFGGGF----
-------------------------GGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMASMKGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLSQIQEMIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-STQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRICSRPPA--GSVRLSAS---G-AGFGAGNGCGV-PGIGSGF-SCAFGGGSS--GG
N------------------LGSASCSAFVGTEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLRNQIISSTTCNASA
VLQIDNARLTA-DDFRMKFENELALHQTVEADVNGLRRVLDELTLCRTDLEIQYETLSEE
LTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCVQLSQIQAQIGALEEQLQQVRTETEGQK
LEYEQLLDIKVYLEKEIETYCRLIDGEDGACKSGSFKSTGYASGVLASQLK-EPPKTIVV
KKVLEEVDQRSKVLTTRLHSLEEKPQSK----------------------

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-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFVAGNVCVG-SGAGSSF-SCTLGGISS----
----GGSFC-NSSGG----LGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHA
LEEANADLEQKIKGWYEKCEP-GSSRGHDHD---YS-RYFSVTEDLKRQIISATICNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTNGLHRVLDELTLCTTDLEIQCETLSEE
LTYLKK--SHEE----------------------EMEVLQCTAGGNVNVEMNATPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--WFNERSATLQQQISDHEGAATAARNELTELKRNLQ
TLEIELQSLMAV----KHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQK
LEYEQLLDVKMFLEKEIEIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAK-DSTEETIV
KTVVEELDQIGNVLSLRVHSVEEKSSKISNITV--EQRVPSKAP------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSSTS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----I------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-ELSVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHREQ--LQMSNTEVSDLRRTLQ---GLEIELQS
QLSMK---AGLEGTLAETEARFGAELAVIQAQISGI-EAQLGDVRADSERQ--NQEYQRL
LDVKSRLEQEIA----TYRSLLEDQEDRY-NNLSASKVL---------------------
------------------------------------------------------------
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---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRNISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSAFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTIEELRDKITATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGGS------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SFRLS
SGSRRICSRAG--AGPGRLSNT---G-TGLGAGNGCGV-AGVGNGF-PCAFGGGPSGGGF
CGGGV--------GG----LGGGACSAFIGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEELKNEIVSVTTCNATI
VLQNDNARLTA-DDFRLKYENELALHQSVEADINGLRRVLDELTLCTTDLEIQYETLTEE
LTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQITDDAGATATARNELTELKRTLQ
TLEIELQSLSAM----KHSYECSLSETEGNYCIQLTRIQAQIEALEDQLQQIRTESEGQK
LEYEQLLDIKIYLEKEIETYCCLIDGEDKACKSSCLKSKGYVPGGSGSQSK-DSTQTTVV
KTVVEELDQRGKVVSLRVHSVEEKSSKISNITM--EQRVPS---------

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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGAATSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------TTTTIRQYTTS-SSIKG--------SSGLG----
----G-----------------G-----SSR------------------ASCRAP-----
---------------GSSFGS--------VSSSRL-------VSG-----GGLG------
--------GGYG------GSCYSGNYSFGSGL----------------------------
GG------------SYGS-----SFG----------------------------------
--SVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTDLE---LKIRDWYQKQAPGP--
---A-KDYSGYYQTIEDLKNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KY-ETELALRTSVEADINGLRRVLDELTLSRADLEMQIENLKEELAYLKKNHDE----
-EMNALRGQV-SGEINVEMDAAPGVDLSRTLAEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--LQSGKSEISELRRSVQ---ALEIELQS
QLSMK---ASLEGSLAETESRYCVQLSQIQGLISSV-EEQLAQLRCEMEQQ--NQEYKVL
LDVKTRLEQEIA----TYRRLLEGEDAHLSQY----------------------------
------KPKEPMTTRQVRTI----VE------------EVQDG--KVISSREQVH--Q--
-----------------------------------STR----------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKATKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGGIG
GGIGG-----------------GSS-RISSVL---------------TGGSYRAP-----
---------------STYGG---------------LSV-SSSRFSSGGA-CGIG------
--------GGYGGGF----SSGSSSFGGALGGGFGG--------------GYGGGLGAGF
GGALG------------A-----GFGGG------------------------------L-
GGG-DGLLVGSEKITMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQKQRPAE--
---T-RDYTPYFNTIEDLRNKIIAANIDNS------------NIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMKSLQGHV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVVTNSEL--V--------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SFRLS
GGSRRICAQA----GSARLPRA---G-SGFGAGSTCAAPGAAESSF-ACTLAGISA----
----AGSAC-QGGGG----SGGSSCGGFLGNEQGLPSGNEKVTMQNLNDRLASYLAHVRA
LEEANAELERKIAGWYDRCGP-ERFPGLGHD---YS-RYFAAIEDLKTQIISVTASNASI
VLQSDNARLTA-DDFKLKYENELGLHQIMEADTSNLRGVLEELTRCAADLEIQRENLAEE
LSCLRK--NHEE----------------------ETRALQGASGGNVNVEMNAAPGVDLA
VLLNNMRAEYEDLAEQNRRDAEA--CFHEKSASLQQQISDDAGAAMAARSQLTEQKRSLQ
TLEIELQSLLAM----KQSYEHTLAETEGNYCVQLQQIQDQIATREEQLQQIRTEMEAQK
LEYEQLLDIKMILEKEIETYCSLLDGEEGRSNSTCCKSKGPKPANSGNQVK-----ETFV
KAMVDELDQLGSVLSLRVHSVEERSSKISNITM--EQRVPPKAP------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---HTQ----GGGGGGG
-------------------GGGGSSFRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSS-GGCLGGSSS-GYGI---------------------SGGF
GGSSFG--GGYGSSSF---GG---GYGGG---SF----G-------------GGSFS---
-GGSFGGGGFGGG--FGG----G-----------------------------FG---GGF
GG-DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--R
QGEP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKTEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGSGYGGG--------------------
----------------------GY---GGGSSGGGYGGGSSG-G-GYGGGSS--GGG---
YGG--------------------GSSGGGHGGGSSGGGHGGGSSGGSSG--G----GFGG
SSGGGFGGSSGGGF-----------------------------GGGSSSGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------VG----------------------LSRSTMS---------
-----------------------------LSAHTSGMPQWLSS---Q-S----VTLGR--
---------------ARGISAS--SI-GSS-----YGGS----AFGFGG---S-----Y-
GGGFTA-A---SM--FASS---SGFGGGSG------------------------------
------------SSFA---GGLGAGYGGARG-----------------------------
---------------------------GGFGSLGIGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANADLE---NKIREWYEIRGSGD--
--PP-NDYSKYQLLIEDLRNKIISESTANA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALCQNVEADINGLRKVLDEMTLARADLEMQIETLNEELAYRKKNHEE----
-EL-SFRAGG-PGEVSVEMDAAPGVDLTSLLNDMRGQYEAVAQQ-NREDAE---ACFIEK
----------------SAELR-KEISSNTEE--LQSSKSVVTDLRRVLQ---TLEIELQS
QLATK---KSLDDSLAETEGDYYSQLSQVRQLIGNV-EEQLLQVRGDAERQ--SADYQLL
LNIKAHLELEIE----TYRRLLDGEAQSDCLDESS---SVTASNSQ--------------
----------------------------------------APST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTR-------A-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVQEIEEII----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSSTS----------SFGGM--
-G-------------------------GGSMR-------FGAGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SSGG--------
------------------------------------------------------------
-----------YGGGYGG-----ALA----------------------------------
--TSDGLLAGNEKLTMQNLNDRLASYLEKVRALEEANGDLE---VKIRDWYQKQGP-G--
---PARDYSHYFKTIEDLRDQILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMSVLKGQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVIAEK-NRKDAE---AWFISQ
----------------TEELN-REVAGHTEQ--LQISKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISGI-EAQLSDVRADTERQ--NQEYQHL
MDIKTRLEQEIA----TYRNLLEGQDAYF-NDLSLAKA---L------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTSYSYRQSSATSSFGG----------LGGGL--
-G--------------------------GSVR-------FGAGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SSAG--------
------------------------------------------------------------
-----------YGGGYGG-----GFAS----G--------------------------L-
-AGSDVLLAGNEKATMQNLNDRLASYLDKVRSLEKANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYFKTIEDLREKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRLGVEADINGLRRLLDDLTLARTDLEVQIENLKEELVYLKKNHEE----
-EISVLRGQV-GGQVNVEVDSAPGVDLAKILSDMRSQYEVLAEQ-NRKDVE---TWYTGQ
----------------IDILN-KEVTSNKEQ--LQISKSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTVAETEARYGAQLAQIQGLISAI-EAQLAEVRADSERQ--NQDYQRL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NDLPTSKV---I------------------
------------------------------------------------------------
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-----------------------------------------------MECQ--NQEYKIL
LDVKCRLEQEIH----TYRCLLEGGQQDLIQQG-GIGQ----------------------
---------------------S---SGLGG-GVARSSGIGGGG--IIRTSHT-YTS----
-----------------SAQIPSC------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------AAAEI-----QVPCRRICD------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------RGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSI--------
----------------------------------RGVSVSSSRFVSSSS----S------
------------GG----------------------------------------------
---------------YGG-----V------------------------------------
LAAADGLLAGKEKLTMQNLNYRLASYLDKVRALQAAKSELE---VKIRDWYQKQGT-G--
---PSHDYSHYYKTIQDLRDKILGATIENS------------RIVLQIHNAHL-AADDFR
T-KF-ETEQALRMSVEANIKALRRGLDELTLARSDLEMQSEALKEELVYLKKSHEE----
-EISVLRGHV-GGQVSVVVDSAPGADLVKILSDMQSQREVLAEQ-NRKDAE---AWFTSR
----------------MKNRT--------------------GRSLRTLQ---RLEIELQS
LLSTK---AGLEGTLAETEAHFGGQLAE----ISGI-EALLGHVRADSERQ--NQEYQRP
MDVKSQLEQEIA----TYRSLLEGQEDRY-NNLSASKVP---------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYGG---------------LSV-SSSRYSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGGLGSGFGG--------------GYGGGLGAGF
GGGL-G-------AGFGA-----GFGGG------------------------------F-
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQRPSE--
---A-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELTLRQSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQT-GGDVSVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSGRSEVTELRRVLQ---GLEIELQS
QLSMK---ASLEGSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHL-SSQQ-GSSHS-Y-SSHNV--FSSSSS----
----------SSSGHQTRPIL---KE---------------------QGSSSFNQGQGS-
------KH----------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------IIASTTSNSNA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCVAGGNVNVEMNAAPGVDLT
VLLNNMRSEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KQSLECSLTETESNYCVQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVLLEKEIETYCLLIGGDDGACKSGGYKTKDYGSGNMGSQVK-DPAKAIVV
KKVLEEVDQRSKILSTRLHSLEEKSQKNVANS---LCSINLPS-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MFCSAQRGSCS-------SRVSS---S-------SSGA-M
---------------GSRVCSAGSTF-SSGSGCGLGGGS----SWGFQGSS-S-----S-
----------------------CGPSGWSK--------------------------GGGF
GGCSVK--GGFGATSG-----------------FGGGS----------------GFGGGS
G--------FGGGSGFGG---GSGFGGGSGF----------G--G-----MGGGLG-G-V
SGSEGGLLSGSEKQTMQNLNDRLATYLDKVRALEEANTDLE---TKIKEWYGKHGSG--K
GESG-RDYSKYWPIIEDLKNQVISATIENA------------RMALQFDNARL-AADDFR
V-KY-EHELCLRECIEADINGLRKVLDDLTMTRSDLEMQIECYTEELVLLRKNHEE----
-EMTCMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEALAEQ-NRQEAE---RQFNER
----------------SASLQ-AQISTDAGA--ANSAKNEVMELRRSVQ---ALEIELQS
QLALK---CSLEGTLADTEASYMAQLSGIQTQISSL-EEQLSQIRGETQCQ--NAEYECL
LNIKTRLEEEIE----TYRRLLNGEGGEC-------DYRNLASRH---------------
-----------------------------------------------------------V
A-----------------------------------------------------------
---------------------------------------------------LNDSRP-GS
C----SGQGKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQVSNI----SEVIIK----------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
SGSRQICLWSG--TGSVRPTSG---G-SGFAGSNACGG-SVAGSGF-SCALGGGLG----
----SVPGGSHAGGV----LGNAACSGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYDKYGP-GSCRGLDHD---YS-RYHLIIEDLKNKIISSTTANANV
ILHIDNARLAA-DDFRLKYENELALHQNTEADINGLRRVLDELTLCRTDQELQYESLSEE
MRYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEAPARWGARSPPPPRHPALQSAILQQQISDHAGAATSARNELTDLKRTLQ
ALEMELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDGNSCS----RSKGLGSGGSGNSPK-ELSKTTLV
KTVVEEIDQRGKVLSSRVHSVEEKTSKVNSGKT--EQKAPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSL--KQYSS---SRS----GGGGGGG
--------------------GGASAHRISSSKGS-------------LGGGFS-----S-
-------R---SF--SRGSSSGGCIGGSSG-GYGG--------------------LGG--
---------GFGG------------RGSYGGGSFGGGYGG----GS----CGGG---GGF
GGGSFGGGSY------GG----GSFGGGSFGG--GGY--------------GGGFG-GGY
GG-DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHSNT--G
RGEP-RDYSKYYDTIDDLKNKVRDIFMPTL--------------L-----------LPME
H-RY-ENELALRQSVEADINGLRRVLDELTLAKSDLEMQIESLTEELQYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDTNIEQ--TSSYKSEITELRRNVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCMQLSQIQTQISAL-EEQLQQIRAETECQ--NSEYQEL
LDIKIRLENEIQ----TYRSLLEGEGSSRGGGRGGGSSGGG-------------------
---------------------------HGGSSGGGYGGSSGG---GY-------------
---------------GGSSGGSHGGSSGGGHGGSSGGGYGGGQG----------------
---GSSGGSHGGSYGG-GSSGG---------------------GGQSGSGGFKGSSS-GS
PGE----SSKGPRSGDTSWGDQ-----------------RQLA-----------------
---------F----SLPCACFLNYRAA---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------ILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQAMRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EVNALRSQV-GGQVSVEVDSVPGTDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------SEELT-REVAVHTEQ--LEAGKTEVTDLRRSMQ---SLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISSI-EAQLSDVRADTERQ--NLEYQQL
MGIKSRLEQEIA----TYRSLLEGQEAHY-NNLPGPKV---L------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRSCSRPTT--ASLRLSGG---G-TSFGAGNACGI-SGIGSGF-SCAFGGS-SSGGN
A------------------AGGNPCSGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANTDLEQKIKGWYEKFGP-GSCRGLDHD---YT-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
ILLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEDKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------SGGGGRSSVKVSSSRGSS-----------SVGGGFS-----L-
GGGSA-------------------------------------------------------
--------------------------------------GG----SY----CYGGSSGGGF
CSGGF----------------------------GGGS--------------GGGFG----
---GGMLLSGNEKVTMQNLNDRLASYLGKVRELEESNFELE---RKIKEWYEKYGSS--T
QREP-RDYSRYYQVIEDLKNQIITLTTDNA------------SVLLQNDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQLESLSEELAYLKKNHEE----
-EMRDLQNVT-TGDVNVEMNAAPGVDLTELLNGMRAQYEQLAEQ-NRRDAE---AWFNEK
----------------SKELT-TEINASVEQ--MSGHKSEITELRRTLQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQVQITSL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLEGEGGENSSSQKIFNCGTKCFSLC--FLFSS-------
------------SGGGYGGRETGSNRT---PVIKTIVEEVGPDG-RVLSSKVESETKKHF
Y-----------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
SSSRRLG--------SMRLPSG---G-AGFGAGGSCGV-PGIGSGF-SCAFGGSASAGAY
G------------------GGSTSCVAFTGNENGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIISATASNANI
VLQNDNARLTA-DDFRMKFENELALHQSVEADINGLRRVLDELTLCRTDLEVQLETLTEE
LVYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRSEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATISAKNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCSQLAQIQAQIGALEEQLHQVRTETEGQK
LEHEQLLDIKVHLEKEIETYCRLIDGDEGSCVKS----K--GHGGPGSQIK-DSPKTAIV
KTVVEEIDPRGKVLSSRVHTTEEKSAKVNKNE----QRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------G------SS------------------RSCRLS-----
---------------GGLGS----------GSCRL-------GSA-----SALG------
------------S-ALGG-SSYSSCYSFGSGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSPYYNAIEDLRNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLSRSDLEMQVETLKEELAYLKKNHEE----
-EMNVLRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MASCSRQFTSS-SSMKG--------SCGIGG---
--------------------------RV---------------------SSCRVP-----
---------------STYGG---------------LSV-TSSRFSSGGA-CGLG------
--------GGYGGGF----SSS--SFGGGYG----S--------------GFGAGLGGGF
GA------------GFGG-----GFGAG------------------------------F-
GG-GDGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFRTIEDLKDKIFTATTENA------------QSVLQIDNARL-AADDFR
T-KY-EHEQALRLSVEADINGLRRVLDELTMTRSDLEMQIESLKEELAFLRKNHEE----
-EMLALRNQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSDL--IRSGRSEVSELRRVLQ---GLEIELQS
QLSMK---ASLESSLEETKGRY--------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLG--------SVRLSSS---G-AALGAGNACGV-PGIGSGF-SCAFGGSSLAGGL
G------------------MGGASCGAFTANEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRTQIISATAHNANI
ILQNDNARLTA-DDFRMKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLSEE
LAYLKK--NHEE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCRLIDGDEGSCVKS----K--GQGGPGNQTK-DSSKTAIV
KTVVEELDPRGKVLSSRVHTLEEKSTKVNK-P----EQRIPS--------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SGSRRSYARPSTGS--L----R---G-ASFGAGNACGV-AGIGSGF-SCAFGGSA-TGGN
T------------------GVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYGSGNAGNQIK-DSVKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------GMGFSGG--SARFGGGMGGG------------------MGVGLG-GGG
FAGDGILLSGDEKVTMQNLNDRLASYLDKVRCLEQENADLE---CRIREWYAKQGPFC--
--EP-RDYSCYYKEIEDLQNQIVCATIDNN------------KIILNIDNSRM-TADDFR
V-KY-ETELALRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEE----
-EMCCLRKQS-TGDVSVEVNACPGPDLRKILEEMRCQYETLIER-NRKEVE---DWYECK
----------------IEEVN-REVITSGQE--VETCNNQVTELRRQLQ---ALEIDLQA
QLSQR---DNLESSLAETECRYNNHLAELQSQITCV-EQQLADLRAEMECQ--NQEYKIL
LDVKCRLEQEIH----TYRCLLEG------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLS-SS-------TSYGG-GFGAGSCQL------
-----------------GG--------------GRKISTCSSRFVSGGSVGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
--------GGSYGGGFCG-----GFG--------------------------------DF
GGGDSGLLSGNEKITMQNLNDRLAIYLEKVRALEAANADLE---VKIRDWHMRQSPTS--
---PERDYSGYYKTIDELRTKILAATTDNN------------RILLEIDNARL-AADDFR
L-KY-ENELSLHQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELVYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLTEMRQQYEALAEK-NRRDAE---EWFQSK
----------------SAELN-KEVSSSAAK--IQTSKTEITELRRTLQ---SLEIELQS
QLSMK---AGLESTVAETECRYALQLQQIQGLISSI-EAQLTELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDANT-TSTSKTSISTSASASG--------------
--------------------------------------------------------RAS-
------NDVRRF------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
----------------------------SYSYRQ----FSASS----------FE--L--
-G--------------------------GSV----------RPE-VFRAPSIHG------
----------------------------------SRVSVSSARFVSSS-----S------
------------SG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDK----------------------------------------------------------NGLRRVLDET--TRTDLEMQIEGLKEELAYLKKNPPE-----EISTLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR----------------TEELN-REVAGHTEQ--LQMSRSEVTDLRRTLQ---GLEIELQSQLSMK---AALEDTLAETEARFGAQLAHIQALISGI-EAQLGDVRADSERQ--NQEYQRLMDIKSRLEQEIA----TYRSLLEGQEDHY-SNLSASKVL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DK---------------------------------------
-------------------NGLRRVLDET--TRTDLEMQIEGLKEELAYLKKNPPE----
-EISTLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGI-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-SNLSASKVL---------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
GGSRHVGIQS----GSLRPPSG---G-AGFAGSSVAGG-SVAGSGF-SWALGGTLG----
----SAPGGSHATGA----LGNVTGVCFMGSEGGLLSGNEKVTMQNLNNRLASYLDNVKA
LEEANSELERKIKTWHEKYGP-GSCRGLDRD---YS-KYHLTIEDLKNKIISSTAANANI
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQISNDLGAATSARTELTELKRSLQ
TLEIELQSLSAT----KHSLECSLAETEGNYCSQLAQIQAQISALEEQLHQVRTETEGQK
LEHEQLLDIKAHLEKEIETYCRLIDGDENSCS----VSKGFESGSSGNSPK-DVSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKMSKMSNGKA--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSSSSKQFSS---SRS----GGGGG--
--------------------GGGGSVRVSSTRGS-------------LGGGYS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG--------------------FG---
-----------------------------GGGSFGGGYG-------------G-SFGGGY
GGSSFGGGSFGGGGSFGG----G-----SFGG--GSY--------------GGGFGGGGF
GGDGGSLLSGNEKVTMQNLNDRLATYMDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYKTIEDLKGQILTLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVTLRQSVEADINGLRRVLDELTLSKSDLEMQIESLNEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEK-NRKDAE---DWFNQK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLDGEGSSSGG--GRGGGSHG-------------------
--------------GSYGG---------GSSGGGSYGGSSGGGG-SH-------------
-----------------GGSYGGGSSGGGSHGGSSGGGYGGGSSSGGA------------
---GGHGGSSGGGYGG-GSSS----------------------GGQGGSGGFKSS---G-
GGD---QSSKGPRY----------------------------------------------
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-----------------------------MSVRYSS-SKQYSS---SRS----GGGG--G
-------------------GGGGSSFRISSSKGS-------------IGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG-------------------------
----LG--GGFGGGNF---GG---GYGSS---SFGGGYG-------------GVSFG---
-GGSFGGGSFGGG-GFSG----GSF---------------------------GGYG-GGY
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--S
QRAP-RDYSKYYQTIEDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRNQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEINSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEGSLAETEGRYCVQLSQIQAQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGS------------------------SGGG-----
---------------GYGGG--RG----GGSSGGGYGGSSGG-G--Y-------GGS--S
GGGGYGG--------GSSGGGGHSGGHSGGHSGSSGGGYGGGSSSGGGGYGG----GSSG
GG-GSHGGS----SGG-G-YG----------------------GGSSSSGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
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-------------------------------------------------MS---------
-----------------------------LSVRTSGLPRRLSS---Q-S----GTSGR--
---------------ARGTSAS--IV-GSS-----YGGS----TLGFGD---S-----Y-
GGGFSA-A---SM--LGSS---SGFGGGSG------------------------------
------------ISFA---GGLGAAYGGALGGGSGAL-----------------G-----
-------------GGFGALGGGFGGLGGGFGGLGIGF---GGSPG----G--GSA--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGSGTGD
PGSQ-SDYSKYYPLIEDLRNEIISASIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALHQSVEADINGLRRVLDELTLARADLEMQIENLTEELAYLKKNHEE----
-ELQSFRAGG-PGEISVEMDAAPAVDLTRLLNNMRAQYEAIAEQ-NRKDAE---AWFIEK
R--------------QSGELR-KEISTNTEQ--LQSSKSEVTDLRRALQ---NLEIELQS
QLATK---KSLEASLAEVEGDYCGQLSQVQQLIGSL-EEQLLQVRADTERQ--NADHQRL
LNAKARLEMEIE----TYRRLLDGEAQGDGFDETL---YVTESKSQ--------------
----------------------------------------TQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------S-----------------RRIK-----------------
---------------TIVQEVVNGEVVSSQVQEELM------------------------
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--------------------------------------------------

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--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------SAYGG---------------LSV-STSRFSSGGA-CGLG------
--------GGYGGGF----SSG-SSFGGGLGSGFGG--------------GFGGGLGGGF
D----------------A-----GFGGG------------------------------F-
GGG-DGLLTGNEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---S-KDYSPYFKTIDDLRNKIMAATTENA------------QSILQIDNARL-AADDFK
N-KY-EHELTLRQSVESDINGLRRVLDELTLSRTDLEIQVESLREELAYLKKNHEE----
-EMNSLRGHV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELPRTMQ---SLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHSLSSQHTSGQ-SHS--SREV--FT--SSSS--
----------SSPSRQTRPIL---KE------------QG---------SSSFSQDQSS-
------KY----------------------------------------------------
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--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYHRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
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-------------------------------------------------M-----SMRFS
SVSKRLDS-------PGRLSGG---A-AGFTAGNACGV-PGIGSGI-SCAFGGSPSAGGY
TLG----------------AGSDPCAAFAGTEHGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIISATVSNANV
VLQNDNARLTA-DDFRLKYENELALHQSVDADINGLRRVLDELTLCRADLEIQLEALTEE
LAHLKK--NHEG----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRTEYEALAEQNRRDAEA--WFNEKSASLQQQISEDTGATTSAKNELTEKKRVAL
ALEIELQSNVAL----KHSLECSLSETEGNYCSQLAQLQAQVGALEEQLHQVRTETEGQK
LEYGQLLDLKVHLEKEIETYCRLIDGDDGSCFRS----K--GQGGPGYQIR-DAPKPIIV
KTVVEETDCRSQVFPSRIQTIEEKPSKINK--N--EQRVSPPRKDSSLN-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------LGTMTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-STSRYSSGGA-CGLG------
--------GGYGGGF----SS-SSSFGGGLGSGFGG--------------GYGGGLGAGF
GG----GF--------GG-----GLGAG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADTNGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ----LEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDLIGNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHYGAGSSGACGRG------GG--GSFGSSYGGG
S-----GGGFSAGSFGGRSR----------------------------------G-----
---------FGGGSGGCFGGGSG-----G-GFGGSGGFYGGGNSSGGGSGGS--------
-HG----------------GGSG----------GSYGGGSS-S----GGGSGGSYGGGSS
SGG---GSGGGYEEGSG---SEGGSG----RSSQSQSYSSKS------------------
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--------------------------MASCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSG-RVSSVL---------------AAGSCRAP-----
---------------SAYGG---------------LSV-SSSRFSSGGA-CGIG------
--------GGYGAGF----SSS-SSFGGALGGGFGG--------------GYGGGLGAGF
----------------GG-----GFSGG------------------------------F-
IAGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---GKIRDWYQRQRPCE--
---S-KDYSTYFQTIEDLRNKIIRATTENA------------QPLLEIDNARL-AADDFR
T-KY-EHELALRQSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EMTALRDQT-GGDVSVEMDAAPGVDLCRILNEMRDQYEQIAEK-NRRDAE---SWFLCK
----------------TEELN-KEVACNSEL--VQTSRSEVTELRRVLQ---GLEIELQS
QLSM--------------------------------------------------------
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--------------------MSLSLLTSGSS-------RQLSS---YSV----GGGGGGG
---------------SVRLSSGG-GF-GSGSKF-VGGYS----GGGYAGGS-L-----A-
----------------------GGYGSGLGGGSGGG-------------------FGGGF
SSSSFA--GGFGGGHG-------GGFGGGHGGGFGGGH----------------G-----
----------------------GGFGGGHGGG------------------FG---G-G-F
GGGDSGLLSGDEKHTMQNLNDRLANYLGKVHALEEANAELE---LKIKDWYAKCS----I
PDTS-RDYTKYFNIIEDLRGKILRQTIENA------------GIVLQIDNARL-AADDFK
L-KY-ENELFLHQNVENDINGLRRVLDDLTMHRSDLELQIEGLNEELAYLKKNHEE----
-ELKSFRGAS-SGDVSVEMDAAPGVDLTKLLNSMRSQYEELAEK-NRQEAE---DQFNKQ
----------------VGALR-QEISANVDQ--LSTGKTEITDLRRTLQ---GLELELQA
QLAMK---QSLEGTLAETERNYCDQLAQIQSQIAGL-EEQLLQLRADMENQ--NSDYQHL
LGIKTRLEQEIE----TYRRLLDGEGGFGSGV----SYG---STSY--------G-----
------------S-TSY----G--------------------ST-G--------------
------------------------------------------------------------
------------------------------------------------------------
S----GGSGTESKK-------T-----------------RKIK-----------------
---------------TVVEEIVDGRVVSSQVKSV----EEKQAT----------------
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-------------------PAFHPPTLQ--------PPRGKA--HLSLTM-----SLRFS
SGSRHICLRSS--TGSVRPPSG---G-ASFAGSNACGS-SAAGSGF-SCVLGGGLG----
----SPAGGNHAGGA----LGNAVCVGFAGNEGGLLSGNEKVTMQNLNDRLASYLDSVRA
LEEANTELERKIKSWYEMYGP-GSCRGLEHD---YS-RYHLTIEDLKNKLISSTTANANV
ILQIDNARLAA-DDFRLKYENELALHQSIDADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EVA-LQCVSSYVVMSAFCV-------
LALLHMRAXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLQ
TLEIELQSLLAT----KHSLECSLTEIEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDLKVHLEKEIETYCLLIDGEGN----SCAKSKGFGSGNSGNISK-DLPKTTLV
KTVVEEIDQRGKVLSSRVHSIEEKTSKMTNGKT--EQRIPF---------

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
---------------------------MSTTFLQ-TS-S---S----------TFGGG--
ST------------------------WGGSLM-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFFSSGSAGGYG------
------------GG------FS-------------G-------------G-AG-------
---------SGLGGGFGG-----GFG--------------------------------DF
GG--GGLLSGNEKLTMQNLNDRLASYLEKVRALEEANADLE---VKIRDWYQKQSPTS--
---PERDYSPYFKTIEELRDKILAATIDNS------------RVSLEIDNSRL-AADDFR
L-KY-ENELALRQSMEADINGLRRVLDELTLARADLELQTESLNEELAYLRKNHEE----
-EMKEFSNQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEIVDLRRTVQ---GLEMELQS
QLSKK---AGLESTLAETECRYALQLQQIQGFIGSI-EARLSELRSEMECQ--SQEYKML
LDTKARLEQEIA----TYRSLLEGQDARM-AGIGTREASL---GGGGS------------
--------------GKVLINVE----------------ESADG--KV----------VS-
------S--RKRD---------------I-------------------------------
------------------------------------------------------------
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--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------------SSR------------------ASCRLS-----
---------------GSLGG----------GSCRL-------GSA-----SGLG------
--------SS-----LGGX-XXXSCYSFGSGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVEGLLAGGEKATMQNLNDRLASYLDKVRALEQANAELE---VKIRDWYQRQAPGP--
---V-RDYGPYYKAIEDLKSKILVASVENA------------NVLLQIDNARL-AADDFH
T-KF-ETEQALRMSVEADINGLRRVLDELTLARGDLEMQIENLTEELAYLKRNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLRWRADAHLTQY---------------------------K
-------PKEPVTTRQVRTI----VE------------EVQDG--KVISSHEQVH-----
----------------------------------QTTR----------------------
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----------------------------MTSRQGTSS-SSMKG--------SYVISGGS-
------------------------S-CGSSAR---------------AGGSFRAP-----
---------------SAYGG-------------------VSSRYSSGGV-CGVG------
--------GGYGGNY------SSSS-------------------------SFGGAMGSGF
GGGYGGGFGGGSGG------------GV---------------------------C--GG
FGGGDGLLVASEK-TMQNLNDRLASYLDDVRALEEANTDLE---VKIRDWYQKQ-PTE--
---I-MDYSAYFRTIEDVR-KILAATVDNA------------NIVLQIDNARL-AADDFR
T-KY-ETELNLRLSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEEXXXX
XXXXXXXXXX-----XXXXXXXXXXXXXXXXDEMREQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVASSSEM--VQSSKSEISELRRTMQ---NLEIELQS
HLSMK---SSLENSLEETKNRYCLQLSQIQGLICNV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDARFPTSQFSSGS--QSSR--DV--T---------
------SS-----SRQIRTK----VL------------DVQDG--KLVSSHEQIVRTKN-
------------------------------------------------------------
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--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGG----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSHYYRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELVYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTH----------------------
------------------------------------------------------------
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--------------------SNLCIDTMSLSVYNSGTSQQASS---R-S----GVGGR--
---------------RLSRLSS-------TSSGGGFGGN----IFGSGA---S-----S-
GGGFSV-V---SM--FGSS---SGFGSTSR------------------------------
------------SAFG---AGLGSGYGAGLGSGFGAG-----------------------
------------------------L-------LGSGY---GGGLG------SASM--GIP
CSNDGVLLSGSEKETMQNLNDRLASYLAKVRALEEANTDLE---NKIRDWYETRVT--GD
SASG-NDYEKYYPLIEDLKNKIISATIENA------------RLILQIDNARL-AADDFR
M-KY-ENEQALRQNVEADINGLRKVLDELTLARADLEMQIESLMEELAFLKKNHEE----
-ELQAIQAGG-PGQVSVEMDAAPGINLTKLLNDMREQYEAIAEQ-NRKEAE---AWFVEK
----------------SGELK-KEISSNTEQ--LQTSKSEITDLKRMLQ---SLEIELQS
QLAMR---KSFEDTLAETESGYCNQLSQIQLQIGNL-EAQLCQVRSDMERQ--NAEYEQL
LNIKTRLEMEIE----TYRRLLEGEGEGNGAIESL---TVPESNSQ--------------
----------------------------------------AHSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTR-------T-----------------RKIK-----------------
---------------TIVQEVVDGKVVTSEVREIEEEI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTSICQFTSS-SSIKG--------SSGLG----
----G-----------------S-----SSR------------------TSCQLS-----
---------------GSLGA----------GSCRL-------GSA-----GGLG------
--------SALG------GSSYSSCYSFGSGGG---------------------------
---------------YGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEADTELE---VKIHDWYQRQAPGP--
---A-RDYSQYYRIIEELQNKILTATVDNA------------NILLQIDNAHL-AAADFR
T-KF-ETEQALCLSVEAGINGPCRVLDELTLARADLEMHIENLKEELAYLKKNHE-----
-EMNAPRGQV-GGEINVEMGAAPGVDLSRILNEMREQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENRYCMQLSQIQGLIGSV-EEQLAQLLCEMEQQ--NKEYKIL
LDMKMRLELEIT----TYHRLLEGEDAHLTQ-----YK--------------------KE
H-----KHLGG-------------------------------------------------
------------------------------------------------------------
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----------------------MSC-RLQTSS-------SGLG------GSCRL------
-----------------GG--------------GRSVSSSSSRFVTSGS----G------
------------GG------M-SCGFDFG-------------------------------
-------------------------G--------------------------------AL
GGADGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANADLE---QKIRDWHLKQSPSS--
---PERDYSHYYKTIEDLRDKIMAATIDNN------------RVVLEVDNARL-AADDFR
L-KY-ENELVLRQSVEADINGLRRVLDELTLAKTDLEMQIESLTEELAYLKKNHEE----
-EMKEFSNQL-VGQVNVEMDAAPGVDLTRVLSEMREQYEAMAEK-NRRDAE---AWFHSK
----------------SEELS-KEVASSTEL--IQTSKTEVTELRRTLQ---GLEIELQS
QLSMK---AGLEATVAETECRYAMQLQQIQGLIGSI-ECQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSKM-PGFTSKNVFCLLPSRRPLTS----------
-------N----VEAQAV---------------------A------LTKAWGPRGRGLR-
----------KR------------------------------------------------
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--------------------------------------------------

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--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GSYGGGF----SS-SSSFGSG----FGG--------------GYG----GGF
GA--------GLGGGLGG-----GLGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
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---------------------------MSCSIKQ-TT--GSLR--GRTSGGSCVIGGGGG
GGGAR-------------------------------------------------------
------------------ISSV---SSGRYTTCGIGS---SRGFS-GRSYCSGVN-YG--
-------------GGLSSGSLVGGSYGGGLG-ATVLGGCS---GIGFSGGSA--RFGGGI
GGGLG------------I-----GIGGGVVG---------------------------GG
FAGDGILLSGDEKVTMQNLNDRLASYLDKVRCLEQENADLE---CRIREWYAKQGPFC--
E--P-RDYSCYYKEIEDLQNQIVCATIDNN------------KIILNIDNSRM-TADDFR
V-KY-ETELALRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEE----
-EMNCLRKQS-TGDVSVEVNACPGPDLRKILEEMRCQYETLIER-NRKEVE---DWYECK
----------------IEEVN-REVITSGQE--VETCNNQVTELRRQLQ---ALEIDLQA
QLSQR---DNLESSLAETECRYNNHLGELQTQITCV-EQQLADLRAEMECQ--NQEYKIL
LDVKCRLEQEIH----TYRCLLS-------QQG-GISQ----------------------
---------------------L---SGLGG-GVARTGGIGGGG--IIRTSHT-YTS----
-----------------SAQMPSC------------------------------------
------------------------------------------------------------
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-----------------------AAAEI-----QAMLR----------------------
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--------------------------------------------------

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---------------------------MSTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGVSFQ-------AGG-G-YFGGGSLYG------
---------------G-GG--------------GRSISASSTRFVSLGLGGGYG------
------------GG------M-SCGFGGGAG-----------------------------
---------GGFGGGFGG-----SFR--------------------------------DF
SGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQSPTS--
---PERDYSHYFQTIEEIRDKILAASINNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARTDLEMQIESLNEELAYLKKNHEE----
-ERKEYGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSTK---AGLENSLAEIECRYATQLQQIQGLISSL-ETQLSELRWEMEAQ--NQEYNML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGTREAFL---GGGGGSS----------
-------S---SSSSKVRINVE----------------ESVDG--KI----------VS-
------S--RKTE---------------I-------------------------------
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-----------------------------MSVRYSS-SKHYSS---SRS----GGGGG-G
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSS-G---SF--SRGSSGGGCFGGSSG-GYGG---------------------L---
--------GGFGGGSF---GG---GYGSS---SFGGGYG-------------G-SFG---
-GGSFGGGSFGGG-SFGG----GGF--------------------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRG-------------------GG-----
---------------SYGGG--Y----GGGSSGGGYGGGSSG-G-GYG------GGYGGS
SGGGYGG--------GSSGGGSSGGG-Y--GGGSSSGGYGGGSSGGGHGGSS--------
GG---------GGSSG-G-GF----------------------GGGSSGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
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--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGS---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-NDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKATKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQYSS---SRS----GGGG---
-------------------GGGGSSLRISSSKSS-------------HGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG---------------------LG--
-GGSFG--GGYGGG------------------SFGGGYG-------------GGSFG---
-GGSFGGGSYGGG-SFGG----GNFGG-------GGY--------------GGGFG-GGY
GGDGGGLLSGNEKVTMQNLNDRLASYMDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYQTIEDLKNQILTLTTENA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLSKADLEMQIESVTEELAYLKKNHEE----
-EMRDLQNVT-TGDVNVEMNAAPGVDLTQMLDNMRSQYEQLAEK-NRKDVE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQGQISAL-EEQLQQIRAETECQ--NSEYQQL
LDIKTRLENEIQ----TYRSLLEGEGSGRGKGGGKGAGI------------SGGG-----
---------------SYGGGR------GGGSHGGSYGGGSSG-G-G--------GSHGGS
YGG------------GS-------SSGGGSHGGSSGGGYGGGSSSGGG------------
-----HGGSSGGGYGG-GSSS----------------------SGQSGSGGFKSSSS-GS
GGD---QSSKGPRSAETSWGNL-----------------N--------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------------------MATTFLQ-T--S---S----------TFGGG--
ST------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGYG------
------------GG------M-SCGFGGG----------------------AG-------
-GGFGGA----FSGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PERDYSHYFKTMEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARTDLEMQIEHLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTHVLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGLISSL-ETQLSELRCEMEAQ--NQEYNML
LDIKTRLEQEIT----TYRNLLEGQDAKM-AGIGAREASL---GGGGSSG----------
-----------SGSSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
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--------------------------------------------------

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--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GA----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISTLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGI-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------MATCSRQFTS--SSMKG--------SCGIGGS--
------------------------S-RV---------------------SSCRGP-----
---------------STYGG---------------LSV-SSSRFSSGGA-CGLV------
--------GGYAGSF----SSG-SSFGGGYG----G------------------ALGI--
--------------NFGG-----GFGGV--------------------------------
---DGGLLAGNEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFRTIEELKSKIITATMENA------------QSILQIDNARL-AADDFR
S-KY-EHELCLRQTVEADINGLRRVLDELTMTRSDLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDISVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRREAE---AWFLRK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHISGGQSYSSRE---------------------
----------SSTSRQPRPIL---KE------------QSS---------ASFSQVQSS-
------RN----------------------------------------------------
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--------------------VD----------------------LSSITMA---------
-----------------------------LSVRTSGLPQRLSS---Q-S----GTLGR--
---------------ARGMSSS--SI-GSS-----YAGS----AFGFGG---G-----Y-
AGGFSA-A---SM--FGSS---SGLGGGSA------------------------------
------------SSFA---GGMGTGYGGAMG-----------------------------
---------------------------GGFGALGLAF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMKNLNDRLASYLDKVRALEEANTELE---NKIREWYETQGSGAGD
PRSQ-NDYSKYYPLIEDLRNKIISASIANA------------QLILQIDNARL-AAEDFR
M-KY-ENELALCQNVEADINGLRRVLDEMTLARADLEMQIENLQEELAYLKKNHEE----
-ELKSFQAGG-AGQVSVEMDAAPGVDLTRLLNDMRAQYEAIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAFK---NLEIELQS
QLAMX---XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX--XXXXXXX
XXXXXXXXXXXX----XXXXXXXXXXXXDSLDESS--YVMTASKSQ--------------
----------------------------------------APST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------A-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGAGNTCGI-PAIGSGF-SCAFGGSSSVGGY
GGG----------LG----GGSVSCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYETLAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCFLIDGEDGSCSKS----K--GYRGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKSTKV-N-KN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSFSYRQ----SSVSS----------SLGGM--
-G-------------------------GGSVR-------FGPGS-ALRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-GAGG--------
------------------------------------------------------------
-----------FGGGFSS-----SFAG----G--------------------------I-
-AGQDALLGGDEKVTMQNLNDRLASYLDKVRALEAANGDLE---LKIRDWYQKQGP-G--
---PTRDHSHYYKTIQDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRKVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EVNALRSQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------SEELT-REVAGHTEQ--LEVSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQAVISSI-EAQLSDVRADTERQ--NLEYQQL
MGVKSRLEQEIA----TYRSLLEGQDAHY-NNLPGPKV---L------------------
------------------------------------------------------------
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------------------------MATTTSTRHFSTS-GSVQG--------LYAPG----
----G-----------------GFS-RVSSVR--------------VGGA-CLAP-----
---------------SLLRA----------GSGGSMSV-TSSRFS-----AGLG------
--------GG---------------YACSLGGGYGS------------------------
---------------------------S------------------------------LG
--VSDVLLGGGEKATMQNLNDRLASYLDKVQVLEEANADLE---VKIRDWYKKQGPGL--
---A-RDYSPYFKTIEDLRSKGLAATIDNT------------SFVLQIDNARL-GADDFR
T-K--GTELNLRMSVEADINGLRRVLDELTLARADLEMQLEGLKEELAFLKKNREE----
-EMLALRGQS-GGNVNVERDAAPGVDLSRILKEMRNQYEKMAEK-NRRDAE---EWFLSK
------------------ELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEMELQS
R--SK---ASLENSLAETEARYGAQLAQLQGLIGSV-EEQLAQVRCDMERQ--NHEYQVL
LNVKTRLEQEIA----TYGRLLEGEDAHLAAQYSS-SL-------------------ASQ
P-----SREGELTSHQVHTI----VE------------EVQDG--RVVSSREQVH--RS-
--------------------------------RH--------------------------
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---------------------------LDHD---YS-RYFPIIEDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------XXXXXXXXXXXXXXXXMNAAPRMD-T
VLLNNMRAEYEDLAEQNRRDA-E--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDEGACKSGGFKSKDYSSGNVGIQMK-DPAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKPQNN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSL--KQYSS---SRS----GGGG---
---------------------GGGAHRISSSKGS-------------LGGGF--------
----SS-R---SF--SRGSSSGGCIGGSSG-GYGG--------------------LGGGF
-----------GGSSY---GG--GSYGGG---SFGGAYA-------------GGSCGGGF
GGGSYGGGGFGGGGSFGG----GSFGG-------GGY--------------GGGFG-GGY
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---SKINEWYKKHSNI--G
GGEP-RDYSTYYNVIDDLKNKILKQTTDNA------------NTLLQIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKSDLEMQIESLTEELQYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKDLT-TEIDTNIEQ--MSSYKSEITELRRNVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCMQLSQIQTQISAL-EEQLQQIRAETECQ--NSEYQEL
LDIKIRLENEIQ----TYRSLLEGEGSGRGGGRGGGSSSG--------------------
-----------------------G---HGGSSGGGYGGSSGG-G--YG------------
----------------GSSGGSHGGSSGGGHGGSSGGGYGGGQG----------------
---GSSGGSHGGSYGG-GSSGG---------------------GGQSGSGGFKGPSS-GS
PGE---S-SKGPRSGDTSGVTR-----------------GSLR-----------------
---------F----LSPVLAF---------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRTISASSARFVSSGSGGGYG------
------------AG------MRVCGFGGGAGSAFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTTEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGGS------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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---------------------------MSCSQRSS---SCLR----GGSGG---------
----S---------------------QHGSASAHRYTASRA-GG-RHAGGSCS-GGSSRS
----------------------------S---CGA---ASFGRMR-RSSYGGGTSGG--M
GGSSYA--GGWR--------------------------------GS----GFGAGYGGSF
G---SGDAGFSVGSFGGG-----GFGG---------------------------------
--ENLGILSNDEKLTMQNLNDRLASYLDKVRSLEKENARLE---QLIREWYQKQGPAG--
---R-KDYSHYYSTIEDLQNQILTATVETN------------KVLLDLDNTRM-TAEDFR
T-KY-ETEYGLRQNVEADINTLRPLLDSLTLTRSDLEMQAESLKEELVGLKKDHEE----
-DMKSLQAQS-SGDVNVEVNAAPGEDLLKKLNDMRQEYEQIIQK-NREEVE---SWYESK
----------------MEEVS-QQVHSSGQE--LESSNQQISVLRRDYQ---SLEIELQS
ELSRV---GALQSNLEDTERRYNMQLQQIQGMIGPL-EEELASIRCEMESQ--NQEYKVL
LGIKTRLEQEIA----QYRSLLEEGQHGIRYAPVLLQP----------------Y-KEL-
------------RGR--QS--ESGPDEGGA-GGGSSGGHGHGG--TSGSSARGGSGGGS-
--------------SWCSGGGSSGG---SGGKTSGGGG--GGSSRG-G---G--------
-CGKA---SGGGGGSG-GGEGGK----------GCMSCGTK---------S-SSSTTRIS
SGG---G-GCG------------SGS----GGGGG----------------------SSC
G--------------------------I---------------------------RKS--
-----------------------------------------GGYSS--------------
--------------------------------------------------------VS--
----------------------------TRKYTS----SGGSGG----------------
-----------------FS-GRSF-GG--------------GG-------SKS--S-YGG
GFSSGSCG--RIGRSSYGGRVS---G-GSYGGGMG----GSMGGGYGSCGGGFGGMGGGY
GG-------GSFGGGSGGYSGGGF--SGFGS-------SGGFG-----------------
-----------G--------------------GSYGGGSFGGVGFG--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSIRYSS-TKQYSS---SRS----GGG----
-------------------GVGGSCHRISGSKGS-------------VCGGFS-----S-
-GGFSG-G---SF--SRGSSSGGCFVGSSS--YGG-------------------------
----VG--GGFSGGGF---GG---GYGSG---SCGGGYG-------------GGSFG---
-GGSFGGGSFGSG--FGG----G------------SF--------------GGGYG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRLLEESNYELE---SKIKEWYEKNGNS--G
QRET-RDYSKYYQTIDDLKNQILNLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--MSSYKSEITELRRNVQ---ALEIELQS
QLALK---QSLEGSLAETEGRYCVQLSQIQAQIAAL-EEQLQQIRAETECQ--NTEYQQL
LDIKTRLENEIQ----TYRSLLEGEGSSGGGRGG--------------------------
----------------YGGS-------SGGSSGGGYGGSS--------------------
-GGG------------------YGGSSGGGHGGGHGGGHGGGSSSGGGHSGS----SGGG
YG-GG--SSSGGGYGG-----------------------------GSSGGGHKSSSS-GS
AGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSAGGYG------
------------GG------V-SCGFGGGAGSGFGGGYGG------GL------------
GGGYGGGLGGGFGGGFAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYYKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHTK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSSAGSVSPRSTSVTTT----------
-------S------SAS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------TSTSMKGSCGIGGSI-
GGSIG-----------------A-------------------------------P-----
---------------AAVSA--------------SGKT-MSLRYSAGSRLLGFH------
--------SGAGP--------GRPSVGFARSSACG-----------------NSVVGSGF
PC----ALGGGLGGAPGG-----SHSTG------------------------------T-
TG-NGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRREAE---DWFFSK
----------------TEELN-REVATNTEA--LQSGRTEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQDMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------AQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------SHEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
-------------------------------------------------M-----SFRLS
SGSRRICSRP----GSVKLSSC---G-AGFGAGNSCGGGSGGGSSF-SSTLVGASS----
----GGSYCGNLSGG----LGSGVCAGFLGNENGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDDD---CS-RYFPIIEELRSQIISATACNANI
VLQNDNARLTA-DDFRLKYENELALHQSVEADINGLRRVLDELTMCTTDLEIQYETFNEE
LTFLKK--NHEE----------------------EMKVLQCSAGGNVSVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRKDAET--WFNEKSASLQQQISDDVGATTAARNELTELKRNLQ
TLEIELQSIMAM----KHSYECSLAETEGNYCLQLSQIQDQIGALEDQLQQIRTETESQK
VEYEQLLDMKIYLEKEIETYCCLIDGEEGXXXXXXXXXXXXXXXXXXXXXX-XSAQSTVV
TTVVEEKDPNGPVLSVKVHSVEEKSSKISNITM--EQRMPSKAP------

------------------------------------------------------------
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-------------------------------------------------M-----SARFS
SASRRLG--------SVRLSGT---G-TALGAGNACGV-PGIGSGF-SCAFGGSSSAGGL
G------------------MGSASCGAFTTNEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRSQIISATANNANI
VLQNDNARLTA-DDFRMKYESELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLTEE
LAYLKK--NHEE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCRLIDGDEGSCVKS----K--GPGGPGNQIK-EPSKTAIV
KTVVEELDPRGKVLSSRIHTLEEKSTKTHTIP----NQSNFQHQWRRNS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYLQ----WSAMS----------SVGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SD--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-E--
---PSRDYSHYYTTIQDLRDNILGATIENS------------RIVLQIENARL-AADDFR
T-KF-ETEQALRMSLEADINGLCRVLEELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGLV-GGQVSVEVDSAPGTDLATILNDIRNQYQVMAEQ-NRKDTE---AWFTSR
----------------TEESN-RELSGHTEQ--LQISRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEVRFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSPLKGQEDHY-NNLFMLLSTQTSQ-----------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCGTKSSSS-TTRI----SSSGGGCGSGSGGG
GGGGSSCGIRKSG-------------GYSSVSTRKYTSSGGSGG--FSGRTFG-GGGSKS
-----------SYGG--------GFSSGSCGRIGR---SSYGRMS-GGSYGGGMGGS--M
GGGYGS--CGGG---------------FGG---MGGGYGG---GGF--GGGSGGYSGGGF
S-GFGGSGGFGGGSYGGG-----SFGGVG-------------------------------
FGEDSGLLSTNEKLTMQNLNDRLASYMDKVRGLEEENAHLE---RLIREWYQKQGPTG--
---S-KDYSQYYRTIEELQNQIVGANVDLN------------RMLLDIDNTRM-TVDDFR
L-KY-ETEYTLHQSVASDINGLRPLLDQLTLSRSDLETQFESLKEELIYLKKNHEE----
-EMRGLQTQS-SGDVNVEVNATPGTNLMEKLNEMRCEYERLIEN-NRREVE---SWYETK
----------------MEEVN-QQVHSSGQE--IQSSNQQISELRREYQ---SLEIELQS
QLSMV---DSLQSNLEDTERRYNMQLQQIQGMIGPL-EEELASIRCEMESQ--NEEYKML
LGIKTRLEQEIA----QYRALLEEGQQDLVIP----------------------------
-------------------------AGGMG-GGMG--GGRIGG--GGFS------GGGR-
--------------G-------------GSG----------------S---I--------
-C----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------GGMG----GGIGGGSGGIGGGSGGIGGGS
GGIGGGSGGSCIIGGGG-SGGGGRTSGGVSS-------SHSYSSSSQS------------
-QSCRGG--GES--------------------QGYGRKSFD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SGSRRSYARPSTGS--L----R---G-ASFGTGNACGI-PGIGSGF-SCAFGSSS-TGGN
T------------------GVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYGSGSAGNQIK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
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------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRSGARPST--GSLRLSSG---G-ASFGAGNACGI-PGIGSGF-SCAFGSSSS-VGN
V------------------GTGSTCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRSEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLSETEGNYCSQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDDGACKSGGYKSKDFGASIMGTQIK-DPIKAIVV
KKVLEEVDQRSKVLTTRLQSLEDKPQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYTSTSKQYSS---SRS----GGGG---
-------------------GGGGSTHRISSSKGS-------------LGGGFS-----S-
-GGFSS-S---SF--SRRSSGGGCFGGSSS-GYGG--------------------LGGGF
SGGSFG--GVFGG----------------------------------------GSFGGGY
GGGSFGGGSFGGS--------------------GYGS--------------LGGF-----
--GDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--G
RREP-RDYSKYYQTIEELKNQIVSLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKSDLEMQIESLTEELQYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKEAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSIKTEITELRRTVQ---SLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLESEIQ----TYRSLLEGEGRSSQGGGHGGGRGGG-------------------
---------------SYGGSHGGS---SG--GGGSYGGGQGGSS-G--------------
-----------------------GGSYGGSHG----GSSGGGGSYGGG------------
-HGGSSGGGHGGSYGG-SSSSAG----------GV---GGGSSGGQGGSGGFKSSSS-GS
TGE---S-SKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------SQ----SSAKS----------SFGGL--
-G-------------------------GGSVS-------LGPGV-------AFC------
------------------A--------------PS----------MHWGRRPRR------
------------FR----------------------------------------------
-----------VLRRFVG-----V------------------------------------
LAASDRLLEGNEKLTMQNLNDRLASYLDKVRALEAANCELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLQDKLLGATIENS------------RIVLEIDNAHL-AADNFR
T-KT-DTEQALRMTVEADINGLHRVLDELTLASTDLEMQIEGLKEELAHLKKNHEE----
-EISGLRGQV-GGQVSVEVDSARGTDLARILSGMRSQYKVMAEQ-NWKDAE---AWFTSR
----------------TEELN-REVAGHTDQ--LHMSLSKVTDLQRTLQ---GLE--LQS
QLSMK---ATLEGTLAETEARVGAQLAQIQSLINGI-EAQLGDVRADSERQ--NQEYQQF
TDNKSRLQQEIA----TYRSLLEGREDHY-NNLSASKVL---------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SVRFS
SASRRLASCGG--AGSVRLSSG---G-AGFGAGNACGV-PGIGSGF-SCAFGGGSSAGGY
GGG----------LG----AGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIISATASNASV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVSVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARSELTEMKRTLQ
TLEIELQSLLAM----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCVKS----K--GYRGPGNQIK-DSSKAAIV
KTVVEEIDPRGKVLSSRVHTMEEKATKV-NNKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLG------
------------S-ALGS-NSYSSCYSFGTGS----------------------------
--------------GYGG-----NFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSAYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSSKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCGV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GRGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKATKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSLSVPGPVLSRRLSA---Q-S----GVVGR--
---------------AWGLPASSLAG-G-------QAGS------APGLGA-G-----W-
AGGFSA-A---SM--FGSS---SGFGGG--------------------------------
--------------------GVGAGHGATLG-----------------------------
---------------------------GSFGGLGMVF---WGSAG----D--GSA--GVL
GSGDGGLVSGSEKATMQNLNDRLASYLEKVHALEVANGELE---QKIREWYDQRAT--RD
PKAR-SDDSKYYPLIEDLRNKIISGSIGNA------------QLVLQIDNARL-AAEDFR
M-KY-ENELALCMSVEADINGLRRVLDELTLAKTDLEVEVESLQEELAFLKKNHEE----
-ELQSF--EG-PGEVSVKMDAAPGVDLTHLLNTMRATYEDLAEQ-NRKEAE---SCFLQK
----------------SQELQ-KEISTNSEQ--LQSGRSEVTDLRRTLQ---SLEIELQS
QLTVK---KSLEDSLAETEHYYSSQLSQVQQLVDHL-EAQLQQVHADAERQ--GAEHQRL
LDAKARLELEIE----TYRRLLDGEAAGDSLIESSA-LTVPDSKSQ--------------
----------------------------------------TPSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RRIK-----------------
---------------TIVQEEVNGQVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGLL--
LL-------------------------G--------------------------------
--------------------------------------------LSLQGQEGLR------
------------GG------MRVCGFGGGAGSAFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PECDYSQYFKTTEELRDKIMATNIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMV---RPPSPHPTPSR---GGSL---NFIQSGLENSLLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGS-------------
------------SSSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------R------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
--------SALR------GSSYSSCYCFGSGGG---------------------------
---------------YGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYYRTIEELQNKILTATLNNA------------NILLQIDNAHL-AAADFC
T-KF-ETEQALRLSVEAAINGLRRVLDGLTLARADPEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGMDLSRILNEMRPDLGEGSRL-TPP--C---PVSCLQ
----------------TEELK-REVATNSEL--VQSGKSKISELWRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENCYCMQLSQIQGLIGSV-EEQLAQLRCETEQQ--NQEYKIL
LDVKTRLEQEIA----TYHRLLEGEDGLLAP----THF--------------------KA
P-----ASPAAVTTHQVGTI----VE------------EVQDG--KVISSHEQVH--Q--
-----------------------------------TTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGGG
---------------GCGGGGGVSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLGGF
GGGSFR--GSYGSSSF---GG---------------------------------SYGGIF
GGGSFGGGSFGGG-SFGG----GGFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGEP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--ISSYKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSFGGG-------------------
----------------YG-G----------GS---SGGGSSGGG-H-------GGGHGGS
SGGGYGGG---SSGGGSSGGGYGGGSSSGGHGGSSSGGYGGG--------SS--------
-------GGGGGGYGG-GSSGGG-------------SSSGGGYGGGSSSGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
SI------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------R-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------A-SCGFGGGAGSGFGG-------------G-FG-------
-CGIGGGFGGG------------------------------------------------F
GGSDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQAPTS--
---PERDYSQYFKTIEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAVPGMDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEMVSNTEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSTK---AGLENSLAETECRYAMQLQQIQGLISGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AAVGIREASL---GGGGG------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------PV----VPAKS----------SFGGLGR
----------------------------GSRE-------SGPRC-SPFAAPSMP------
---------------------------------LG---RQAAVA----------------
------------------------------------------------------------
-------------SVSFG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDGLASYLDKVRALEA----LE---VKIRDWHQKQGP-G--
---PSRDYSHYYKTIQDLRDKLLGATIENS------------RIVLEIDNARL-AADNFR
T-KT-ETEQALRMTVEADINGLSRVLDELTLASTDLEMEIEGLKEELAYLKKNHEE----
-EISRLRGQV-GGQVSVEVDSAQGTDLARILSDMRSQYKVMAGQ-NWKDVE---AWFTSR
----------------TEELK-REVAGHTDQ--LQMSLSKVTDLRHTLQ---GLE--LQS
QLSMK---ATLEGTLAETEARVGAQLAQIQPLINGI-EAQLGDVRADSEGQ--NQEYQQF
TDIKSRLQREIA----TYRSLLEGQEDHY-NTLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQTSS-------STYGS-GFGGGSCQL------
-----------------GG--------------GRGMSSCSSRFVSSGSMGGYG------
------------GG------M-SCGFGGGAGSGFGGGFCG------GAGG----------
------GFGGSFGGSFGG-----GF---------------------------------DL
GGGDGGLLTGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWHLKQSPTS--
---PEKDYSPYYKTIEELRAKIQEATIDNS------------RTILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIEGLNEELAYIKKNHEE----
-EMKEYSNQV-VGQVNVEMDATPGIDLTRTLAEMREQYEALAEK-NRRDAE---NWFQQK
----------------SEELN-KEVTTNTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLEASVAETECRYAMQLQQIQGLISSI-EAQLSDIRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLDGQDSKM-TGFTTSGTTSISSNSSSSAN----------
-------V-----S----------------------------------------------
-------AGTRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------ILAATIDNS------------RVILEIDNARL-TVDDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKADLEMQIEGLKEELAFLKKNHEE----
-XXXXXXXXL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFHSK
----------------TEELS-KEVATNTEM--MQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGIIGSL-ETQLGELRCEMEQQ--SQEYNML
LDVKTRLEQEIA----TYRRLLEGEDAKM-AGVGSRGASL---GGGGGGG----------
------------SSSKVRVNVE----------------ESVDG--KV----------VS-
------S--HNRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRVSS---S-------RAGGSS
---------------SARVSAGGSSF-SSGSRCGVGGSS----AQGFRGGA-M-------
---------------------------GSSGAFGGG-------------------FEGGF
GG---G--FGFGGASG-----SGAGFGGGSS--LGGVS----------------G-----
---------FGRGSGFCG---SSGFSSGASGG----FYSYGGG-------M----G-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEKANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEDLRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLQQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELTYLKKNHEE----
-EMKDMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ATYAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQISAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEVEIE----TYRRLLDGERGGS-------SFAEFGGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIVEELVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SGSRRSSPRSGT--GSLRLSSG---G-ASFGAGNACGI-PGIGSSF-SCAFGGSSS-MGN
A------------------GTGNPCAGFAVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANTDLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRQDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLSETEGNYCSQLAQIQARIAALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDEGACKSGGYKSKDFGASNMGNQIK-DPIKAIVV
KKVLEEVDQRSKILTTRLHSLEDKPQNN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLCG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSVFGG-------------G-FR-------
-GGVGG----G------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIHDWYQKQTPTS--
---PECDYSQYFKTIEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADVNGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGIREASS---GGGGS------------
-------------SSNFHINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSAGGYG------
------------GG------V-SCGFGGGAGSGFGGGYGG------GL------------
GGGYGGGLGGGFGGGFAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYYKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSSAGSVSPRSTSVTTT----------
-------S------SAS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSAGGYG------
------------GG------V-SCGFGGGAGSGFGGGYGG--------------------
------GLGSGFGGGFAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIREWHLKQSPAS--
---PERDYSPYYKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSSAGSVSPRSTSVTTT----------
-------S------SAS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGTGNSCGI-SGIGSGF-SCAFGGS-SSGGN
T------------------GGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MATTTSIRQFSTS-SSVKG--------LCAPG----
----G-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGNMSI-TSSRFS-----AGLG------
--------SSYG-------G----GYTCSLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGGEKETMQNLNDRLATYLDRVHALEEANTDLE---VKIRDWYKKQGPGP--
---A-RDYSSYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQQL
LDVKTRLEQEIA----TYRRLLEGEDTHLATQYSSS-M-------------------ASQ
P-----SREGMVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYG---------------GLSV-STSRFSSGGA-YGLG------
--------GGYGGGF----SSSSS-----YGGGFGG--------------GYGGGLGAGF
GG----GLGAGFG----G-----GLGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGP---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-NDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGSF--
-G-------------------------GGSVR-------FGSGG-AFRAPSIHG------
---------------G-SG--------------GRGISVSSARFVSS-SS----------
------------------------------------------------------------
------------AGGYGG-----GYGG----V--------------------------L-
-AGSDGLLAGNEKVTMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYFKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISALRGQV-GGQVNVEVDSTPGIDLAKILNDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------TEELN-REVAGHSEQ--LKMSESEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYGARLAQIQARISSI-EAQLGDVRADTERQ--NLEYQQL
MDIKSRLEQEIA----TYRSLLEGQDAHY-NNLPNV------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG---------------LSV-TSSRFSSGGA-CGMG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GFGGGFGAGF
G------------VGFGG-----GFGAG------------------------------F-
GVGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPSE--
---I-KDYSPYFRTIEDLRNKIITATMENA------------QPILQIDNARL-AADDFR
T-KY-EHELTLRQTVEADVNGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFISK
----------------TEELN-KEVASNSEQ--IQSGRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYNIL
LDVKTRLEQEIA----TYRRLLEGEDSHSS-SQH-SSGQS-Y-SSREV--FSS-------
------------SSHQIRPIL---KE---------------------QSSSSFSQSQSQ-
------SQSSRN------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRISS---S-------RAGGRS
---------------SARVSAGGSSF-SSGSRCGLGGSS----AQGFPGGA-R-------
---------------------------GSSGAFGGS-------------------LGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSSGASGG----FYSYGGG-------M----G-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEDLRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLKENHEE----
-EMKNMQGIS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQISAL-EEEICQIRGETKCQ--NTEYEQL
LDIKTHLEVEIE----TYRRLLDGEGGGS-------SFAEFGGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-T--S---S----------TFGGG--
ST------------------------RGGSLR-------AGG-G-SFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGYG------
------------GG------M-SCGFGGG----------------------AG-------
-SGFGGT----FGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PERDYSHYFKTMEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEANINGLRRVLDELTLARTDLEMQIEHLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGLISSL-ESQLSELRSEMEAQ--NQEYNML
LDIKTRLEQEIA----TYRNLLEGQDAKM-AGVGVREASL---GGGSGGS----------
-----------SSSSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MPGP--------PLPRSIKPGILSELSH
RAPFSS---LCDLLTR-S-LTSLLGTMATCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSIL---------------GGGSYRAP-----
---------------SAYG---------------GLSV-TSSRYSSGGV-CGLG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GYGGGLGAGF
G--------GGFG----G-----GFGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---S-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELISGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTS-TRQIRT-K---VM------------DVHDG--KVV------S-----
---------SHEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
GRPSHICFRPG--SGSARLPSG---G-T---RSTMCGS-FVAGTGF-SCALGGGMD----
----SVPRGAYAGGA----LRSAACVGFAGSEGGLLSGNEKVTMQHLNDRLASYLDSVRA
LEEDNTELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHVTIEELKNKVISATTANANV
ILQIDNARLAA-DDFQLKYENELALHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKR--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEKNRRDAEA--WFNEKSASLQLQISHDAGATTSARNELTELKRTLQ
TLEIELQSRLAT----KHSLECSLTETEGNYCAQLAQIQTQIGALEEQLHQVRTETEGQK
LEYEQLLDIKSHLEKEIETYCRLMDDNGNSCS----KSKNFGSGSSGNSSK-DLSKTTLV
KTVVEELDQRGKVISSRVHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
SN------------------------RAGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGSGGVYG------
------------GG------M-SCGFGGGAGSGFGG-------------G-F--------
----GGGVGGGFGGSFGG-----G-----------------------------------F
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPTS--
---PERDYSHYFKTMEELRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYMKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRALAEMREQYEAMAEK-NRREAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCDMEAQ--NQEYKVL
LDIKTRLEQEIA----TYRSLLEGQDTNG-PAAASASLAF---GPLSR------------
-----------G----LRPSKQ-------------------AA--KG----------FL-
------S--F--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFVAGNVCVG-SGAGSSF-SCTLGGVSS----
----GGSFC-NSGGG----LGSGACSGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVRA
LEEANADLEQKIKGWYEKCEP-GSSRGHDHD---YS-RYFSVIEDLKRQIISATTCNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIHCETLSEE
LTHLKK--NHEE----------------------EMEVLQCTAGGNVNVEMNATPGVDLT
LLLNNMRAEYEDLAEQNCKDAEA--WFNERSATLQQQISNDEGAATAARNELTELKCNLQ
TLEIELQSLMAV----KHSYECSLAETEGNYCNQLQQIQDQIGVREEQLQQIRTETEGQK
LEYEQLLDVKSF-RKEIEIYCNLLDGEERKSKSTCYKSKGCRPVNSGNQGK-DSAKETIV
KTVVEELDQIGSVLSLRVHSVEEKSSKISNITV--EQRVPSKAP------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------RS----------------------NPATAMS---------
-----------------------------RSGCTSGLLYQLSS---Q-N----GTTSR--
---------------ARGMSAS--SI-GSG-----YGGS----TAGFGG---N-----C-
GGGFSA-P---SM--FGSS---SVLGSGSG------------------------------
------------SYFA---GGLG-------------------------------------
---------------------------SGFRGLGTGF---GGSPV----G--GFL--SIL
SGSDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETQGSETGD
SGSQ-NDYNKYHPLIETLRNKIISASIGNA------------QLILQIDNARL-AAEDFR
T-KY-ENELALRQGVEADIHGLRRVLEELTLARSDLEVQMESLTEELAHLKKSHEE----
-ELQSFRAGG-TSQVSVEMDAAPGVDLTGLLNDMRTQYEAIAEQ-NRKDVE---AWFNEK
----------------TRELR-KEISTNTEQ--LQSSKSQVADLRRQFQ---SLEIELQS
QLAMK---KSLEDSLAETEGDYCSQLSQVQQAIEGL-EAQLLQVHADAECQ--NADHQRL
LNIKARLELEIE----TYRRLLEGEAEGNSVDESS---SVIDSKFE--------------
----------------------------------------TQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPSK-------T-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVQETEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------MPVSFSSASKRL-----G----------------------
---S-----------PGRL------SG----GRPSFQAGKPCG-----------------
-------------------------VTGT--GSGFSCALGGSWSAG--------------
----------------ALGTGSAPCAVLDGTEHGLLSGN-EKVTMQNLNDRLASYLDKVR
AL---EEANADLEVKIKGWYDKFGPGSCRGLDRDYSRYFPIIDDLQNQIISMTASNSNVV
LQNDNASLATDDFRLKYENEQALHQSVEADLNGLRRVLDELTLCRADLEIQLESLTEELA
HLKRSHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLSNMRAEYEALAEQNRRDAEAWFS
KKVQRL RAGRTGVLSCQGGPGAEAVRTPDPASIL QSASLQQQISEDSGAATLARNELLEM
KRIAQGLEIELQSSVALKHSLECSLSETEGHYCSQLAQIQAQIGALEEQLHQVRTETEGQ
KLEYEQLLDVKVHLEKEIETYCRLI-----------DGD EGV-LGCAVAM-----SFRFP
NGSRRICSQA----GPARLSRV---G-SGLRAGSACVTPGA-EGSF-ACTLEGVSP----
----GGNSC-HGGGG----SGGGICTGFLGSEQGLLSG NEKVTMQNLNDRLASYLAHVHA
LEEANADLEVKIAGWYDRYGP-ERFPGLGHD---YS-RYFSAIEDLKKQIISVTACNASI
VLQNDNARLTA-EDFKLKYENELGLHRIMGADTGSLRRALEELSLCITDLEVQRESLGEE
LTSLQK--NHEE----------------------ETKALQCASGGNVNVEVNAAPGVDLT
ALLNNMRAEYEDLAEQNRRDAEA--CFHEKSACLQQQILDDAGAATAARNQLMEQKRSLQ
TLEIELQSLLAM----KQSYGHALAEVEGNYCVQLQQFQDRIGTMEEQLQQIRTETEGQK
LEYEQLLDIKMILEKEIETYCSLLDGEEGRNKSMCYKSKGPRLVNSGNQVK-DLTEETFV
KAMVEELDQLGNVLSLRVHSIEEKSSKISNITM--EQRVPAKAP------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCR-------ASVSS---S-------SWAR--
---------------------GSKQA-GSGCSYGLGGGS----AWSFQGGA-G-----S-
----------------------CGLSGGSSGGSGGG-------------------LGGGF
GSCSVG--GRWGAGTG-----SGASFGKGSC-----------------------------
---------LGGGSGFSG---GFGFSGGASGG----FG----S-------SGGGFG-G--
DAGDGGLLSGNEKLTMQNLNDRLASYLDKVRALEDSNTDLE---IKIKEWYERFGPGSRD
GGSR-RDYSNYYAILDDLRKQMVAATIENA------------RISLQIDNARL-AADDFR
L-KY-ENERCLRQGVDADISGLRRVLDDLTLAKADLEMQIEDLQEELVILKKNHEE----
-EMRSAQGSS-GGDVSVEMNAAPGTDLTQLLNDTRAQYEQLAEQ-NRRDAE---QQFNRQ
----------------SASLQ-AQISTDVGA--ASSAKREITELKRTLQ---ALEIELQS
QLAMK---SSLERSLADTEASFSAQLSGIQMKIDSL-EEQICQVRGETECQ--NREYEVL
LDIKTRLEREIE----TYRRLLNGEGGGSG-FERSRD-----------------------
-----------------------------------------------------------L
V-----------------------------------------------------------
---------------------------------------------------SSASR----
P----ASQERDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGRVISSQVSSI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
SASRRLGSCGG--AGSVRLSSG---G-AGFGVGNACGV-PGIGSGF-SSAFGGSSS----
----A--GGYGGGLG----GGSASCAAFSGNEHGLLSGNEKVTMQNLNDRLASYLDHVRA
LEEANADLEQKIKGWYEKFGP-GVCRGLDHD---YS-RYFPIIDDLRNQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXELT-RWGEGEVQLETLGEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VQLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCHLIDGED--------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGAGF----SSS-SSFG----SGFGG--------------GYGGGLGAGF
GGGF-G-------A---------GFGGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QSSSSFSQGQSS-
------QN----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAAS----------SFGGL--
-G-------------------------GGSVR-------FGAGG-SFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SS----------
------------------------------------------------------------
------------SGGYGG-----GYGV----A--------------------------L-
-AGSDGLLAGNEKITMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYFKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLELQIEGLKEELAYLKKNHEE----
-EISALRGQV-GGQVSVEVDSAPGIDLGKILSEMRSQYEVMAEK-NRKDAE---AWFNSR
----------------TEELS-REVAVNTEQ--LKSSRSEVTDLRRTMQ---GLEIELQS
QLSMK---AALEGTLAETEARYGAQLAQIQAVISSI-EAQLSDVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRSLLEGQDAHY-NNLPTSKV---I------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RFQSSS-------MSYGG-GFGAGSCQL------
-----------------GG--------------GRNISSCSSRFVTGGSAGGYG------
------------GG------M-SCGFGGGAGGGFG-------------------------
-----GGFGGGYGGGFGG-----GFG--------------------------------DF
GGVDGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLE---VKIRDWHLKQSPAS--
---PERDYSAYYKTIEELRIKILEATTDNN------------RIVLEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGVDLTRVLTEMREQYEALAEK-NRRDAE---EWFQAK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFNSGGNNTTTSNGS-PS-----------
--------------SNSG---------------------R-------P-----DFRKY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SFRLS
GGSRQICSRA----ASVRLSGG---G-TGFVAGNVCVG-SGAGSSF-SCTIGGISS----
----GGSFC-NGGGG----LGSGVCTGFLGNEHGLLSGNEKVTMQNLNDRLASYLDHVRA
LEEANADLEQKIKGWYEKCGP-GSFQRHDHD---NS-RYSSVIEDLKRQIISVTSCNASI
VLQKDNARLAA-DDFKLKYENELALHQSVQADTNNLRRVLDELTLCITDLEIQCETVSEE
LTYLKK--NHQE----------------------EMQVLQCVAGGNVNVEMNAAPGVDLT
VLLNSMRAEYEDLAEQNRKDAEA--WFNEKSATLQQQIFDDAGAATAARNELTELKRNLQ
TLEIELQSLLAM----KHSYECSLAETEGNYCDQLQQIQDQIGAMEEQLQQIRTETEGQK
LEYEQLLDIKIFLEKEIEIYCNLLDGEERKCKSSCYESKGCKPANSGNQVK-DSTEETVV
KTVVEELDQLGNVLSLRVHSVEEKSSKISNITV--EQRVPSKDHNEKKLL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVRTSALSRRSSS---Q-N----GVAGR--
---------------PWGASAS--SV-ACG-----YGGT----ASGFGV---G-----C-
GGLLSA-A---SM--FGSS---SGFSGGST------------------------------
-------------GCS---PGLGTAYGGPLGAGVGGM-----------------------
-----------------------------------GI---GGSSG----G--GSL--CIF
SGNDGGLLSGSEKETMQNLNDRLASYLGKVRALEEANAELE---NKIREWYETRRT--GD
SGSQ-SDYSKYYPLIEDLKNKIISASVSNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRRVLDELTLARADLEAQTENLTEELAYMKKNHEE----
-ELQSFQAGG-PGEVNVEMDAAPGVDLTKILNEMRAQYEAMADQ-NRKDAE---AWFLEK
----------------SGELR-KEINSNTEQ--LQSSKSEVTDLKRMVQ---NLEIELQS
QLAMK---SSLEGSLAETEGGYCCQLSQMQQLIGSL-EEQLQQLRADAERQ--NEDHQRL
LGVKARLEMEIE----TYRRLLEGDSQGDGFDESL---SLTVSKP---------------
---------------------------------------QAPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVQELEEAM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RFQSSS-------TSYGG-GFGAGSCQL------
-----------------GG--------------GRKISTCSSRFVTGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
GGSCGGGFGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLISGNEKITMQNLNDRLANYLEKVRALEAANADLE---VKIRDWHMRQSPAS--
---PERDYSAYYKTIEELRNKILEATTDNN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFQRQ
----------------SAELN-KEVSSSAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-ETQLSDLRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSKM-TGFSNAGGNGTASSSNASVS----------
-------P------STSG---------------------R-------L-----DFRKY--
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------MAATTTSIRQFSSS-GSVKG--------LCVPG----
----G-----------------GFS-RTSSVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGNMSV-TSSRFS-----TGFG------
--------GGYG-------G----GYTCNLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGGEKETMQNLNDRLASYLDKVRALEEANADLE---MKIREWYKKQGPGP--
---A-PDYSHYFKTIEDLRSKILAATIDNA------------SLVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QISMK---ASLENSLAETEARYGAQLAQLQGLISSI-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDSHLASQYSSS-L-------------------TSQ
P-----SREATVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-TS-S---S----------SFGGS--
SS------------------------RGGSLR-------AGG-G-SFGGGSLSG------
---------------G-GG--------------SRSVSASARFVSSSGSGGGYG------
------------GG------L-SYGFGGGFCGGFGG-------------G-LG-------
-GGFG-----------GG-----GFG--------------------------------DF
GGGDGVLLAGNEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQSPAS--
---PERDYSRYYKEIEELRDKILASTIDNS------------RVILEIDKPGWLPMTSGS
S-KY-EHELALRQTVEADINGLRRVLDELTLSKTDLEMQIESLQEELAYLRKNHEE----
-EMKEFNSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTGKTEVTELRRTLQ---GLEIELQS
QLSMK---AGLEGTLAETECRYATQLQQIQGLIGGV-EEQLAQLRCEMEQQ--SQEYNML
LDVKTRLEQEIA----TYRSLLEGQDAKM-ASVGSRE---AVLGGGSS------------
------------GGGSFRIKVE----------------ESVDG--KV----------VS-
------S--HKRD---------------V-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-T--S---S----------TFGGS--
ST------------------------RGASLR-------AGG-G-SFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGFG------
------------GG------M-SCGFGGG----------------------FG-------
---------GGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PDRDYSHYFKTMEEIRDKILAATIDNS------------RVVLEIDNARL-AADDFR
L-KY-ENELTLRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGVITGL-ETQLSELRCEMEAQ--NQEYNML
LDIKTRLEQEIA----TYRNLLEGQDAKM-AGIGVREASL---GGSSGG-----------
-------GGSSSSSSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSSF-SCALGGS-SSGGN
A------------------VGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KRSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDHGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LPAHTSGLCRRLSS---Q-N----GVAGG--
---------------PRGFSAS--SI-GSG-----YLGS----ALGFKA---G-----C-
GGGFST-A---SM--FGGG---SG------------------------------------
-------------SSL---AGLGTGYGGSLG-----------------------------
---------------------------GGFGGLGMGL---GAGSG----G--GSL--SLL
AGSDGGLVSGSEKATMKNLNDRLASYLDKVRALEEANAELE---NKIRDWYEARGTGSVD
SGSQ-SDYSKYYPVIEELRNKIISASIGNA------------QLILQIDNARL-AADDFR
M-KY-ENELALRQTVEADINGLRRVLDELTLTRADLEMQIEGLKEDLAYMKKNHEE----
-ELQSFQAGG-PGDINVEMDAAPGVDLTRLLNDMRSQYEAMAEQ-NRKDAE---AWFLEK
----------------SGELR-KEISVNTEQ--LQSSKSEVSELRRALQ---NLEIELQA
QLAMK---KSLEDTLAETEGGYCGQLSQVQQLIGSV-EEQLQQVRADAERQ--NADHQRL
LDAKARLELEID----TYRRLLDGEMQGDGFDDSL---FVTASKSA--------------
----------------------------------------APSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSSDPSK-------T-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSKVQEVEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQYSS---SRS----GGGG--G
-------------------GGGGSSFRISSSKGS-------------IGGGFS-----S-
-GGFSG-G---SF--SRGSSSGGCFGGSSG-GYGG-------------------------
----LG--GGFGGGNF---GG---GYGSS---SFGGGCG-------------GGSFG---
-GGSFGGGGFGGG-GFGG----GSF---------------------------GGYG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYQTIEELKNQILSLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVDADINGLRRVLDELTLAKADLEMQIESLTEELAYLKKNHEE----
-EMKDLHNVS-TGDVNVEMNAAPGVDLTELLNNMRNQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEINSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLESSLAETEGRYCVQLSQIQAQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSS-----------------------SGGG-----
---------------GYGGG--RG----GGSSGGGYGGGSSG-G-G--------------
------------------------------------------------------------
---------------------------------------------------HKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MSTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYGG---------------LTV-SSSRFSSGGA-CGMG------
--------SSYGGGF----SSSSSSFGGGLGSGFGR--------------GFGGGFGGGF
GGGLV------------G-----GFGG---------------------------------
---GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPSE--
---I-KDYSSYFHTIEDLRSKIVAATLANA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-REVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLISGV-EEQLAQLRCEMEQQ--SQEYNIL
LDVKTRLEQEIA----TYRRLLDGEVVHSS-SQH-SSGQSYSSRE--G--F---------
-----------SSSHQPRSIL---KE------------QGS---------SSFSQSQSQ-
------SSRN--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSM--------KGSCGIGGGSS
R--------------------------ISS---------------VLAGGSCR-------
----------------------------------AP-----------STYGGLSVSSSRF
SS---------------------GGACGLGG-GYGGGFSS---SSSF-GGALGSGFGGGY
GGGFGGG--L------GG-----GFG--------------------------GGFG--GG
FGGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQRPTE--
---I-RDYSPYFKTIEDLKNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLNEELAYLKKNHEE----
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXXXXX---XXXXXX
----------------XXXXX-XXXXXXXXX--XXXXXXXXXXXXXXXX---XXXXXXXX
XXXXK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSSSQFSSGS----------------Q-SSR-
--DV------TSSSRQIRT--K--VMD------------VHDG--KVVSTHEQVLRT---
--------------------K-N-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NLCRSIMSCS-------SRISS---S-------RAGGSS
---------------SVRVSAGGSS---SSSRCGLGGSS----ARGFRGGA-G-----S-
----------------------CGLSGGLSGG-----------------------FGGGF
GSCSVG--GGFGGASG-----SGLGFGGGSG--FGRGS----------------GFGGGS
G--------FGGGSGFGG---GSGFGGGASGG----FYNYGGG-------LG-----G--
GTGDGGLFSGDEKQTMQNLNDRLANYLDKVRALEEANADLE---NKIKEWYEKYGPGSGD
GRSG-RDYSKYYPIIEDLRNQIITASVENA------------GMVLQVGNARL-AADDFR
L-KY-ENELHLRQAVEADINGLRKVLDELTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKNMQGSS-GGGVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---NSLEGTLADTEANYMAQLSEIQMRISSL-EEQICQIRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGG----FGGS-DFKNSGSRNM--------G-----
------------------------------------------SR-DS------------T
------------------------------------------------------------
---------------------------------------------------SGDSKS-GS
H----SSQGRDP---NK----T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSHVSNI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MS-------------------------------
---------------------------VRYSSSKQYSSSRSGGG-GGGGGGGSSLKISRS
------------------------------------KGSSGGGYS-SRGFSGGSCSRGSS
GGSMLGTVFGSHGGGFGESSFGGGSFCGG-G-GFGGGGFG---GGSYGG--------GSY
GGGSFGGGSFGGGSFGGG-----SFGGGSFG---------------------GGYG--GG
FGGDGGLLSGNEKTTMQNLNDRLASYLDKVRALEDSNHELE---SKIKEWYEKHGHTG--
QGET-PDYSNYYKTIQDLKKEILDRTIDNA------------NVLLQADNARL-AADDFR
M-KY-ENELTLRQGVEADINGLRRVLDELTLAKSDLEMQIESLTEELSYMKKNHEE----
-XXXXLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQVAEQ-NRKDAE---NWFNEK
----------------SKELT-SEIDSNIQQ--VSSYKTEITDLRRTVQ---GLEIELQS
QLALK---QSLEASLA-TDARYCVQLAQIQAQITAL-XXXXXXXXXXXXXX--XXXXXXX
XXXXXXXXXXXX--------XXX-----XX------------------------------
-----------------XX--XXXXSGGGG-GGGGYGGGGYG------------------
------------------------------GGSSGGGGYG--------------------
-YGGG---SSGG---------------------GXXXXXXX-XXXXXXXXX-XXXXXXXX
XXX---X-XXX------------XXX----XXXXX----------------------XXX
X--------------------------XXXXXXXXXXXXXX---XXXXXXXXXXXXXX--
-----------------------------------------XXXXX--------------
--------------------------------------------------------XXX-
--XXX-----------------------XXXY----------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRLS
SGSRRSGPRTTA--GSLRLSGG---G-ASFGAGNACGI-PGIGSGF-SCAFGGS-SSGGN
V------------------GGASSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLXXXXXXXXX-XXXXXXYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLATTHTLKHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGSYKSKDYGSGNMGNQVK-DPAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSXXX------
---------------X-XX--------------XXXXXXXXXXX---XX----X------
------------XX----------------------------------------------
-----------XXXXXXX-----X------------------------------------
XXXXDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
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-------------------------------------------------------Q----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSSRTEITELRRTVQ---NLEIELQS
QLSMK---ASLEGSLAETEARYGAQLAQLQGLISSI-EAQLSELRCDMERQ--NQEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLSTQYSSS-L-------------------VSQ
P-----TREGTVTTRQVRTI----ME------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
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--------------------------------------------------

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---------------------------MSCS-------TRVSS---S-------RARGSS
---------------SVRVSAGGSSF-SSGSRCGLGAGS----APGFRGGA-G-----S-
----------------------CGLSGGSSSGFGGS-------------------FRGGF
GSCSVA--GGFGGASG-----SVAGYGGGSG--FGGGS----------------GFGGGS
G--------FGGGSGFGG---GSGFGGGASGG----FYSYGGG-------LG-----G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANADLE---HKIKEWYDKFGPGSRD
VGSG-RDYSKYYPIIDDLRKQITAATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLRQSVEADINGLRKVLDDLTMTRSDLEMQMENLVEELTYLKKNHEE----
-EMKSMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFKKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLVMK---SSLEGTLADTEAGYMAQLSQIQIQISSL-EEQICQIRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-GFGGC-DFRNSGSRNT--------G-----
------------S-RNI----G--------------------SR-DS------------S
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SVQGRDP---SK----S-----------------RVTK-----------------
---------------TIVEEVVDGKVVSSQVSNI----SEVKL---------K-------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTANEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKATKV-NNKN--EQRVPS---------

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---------------------ILSLTTDNA------------NVLLQIDNARL-AADDFR
M-KY-ENEVTLRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEK-NRKDAE---AWFNEK
----------------SRELT-TEIDSNIEQ--MSSHKTEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQGQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGSYGGGRGGSSS------------G-----
------------CHGGYGGGSSLR------G-----------------------------
----------------------------------HGGGYEGRLSYDHGDGVH----SGKS
LRGQGDGGSRG-------------------------------------------------
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--------------------------------------------------

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--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EINTLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGI-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------------MTTCSRQFTSS-SM---------K-------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYG---------------GMSV-TSSRFSSGGA-CGMG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GFGG------
----------GFGGGFGG-----GFGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---I-KDYSSYFKTIEELRNKXXXXXXXXX------------XXXXXXXXXXX-XXXXXX
X-XY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQEMIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSS---------------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VV------------DVHDG--KVVSS--HEQ-----
---------VL---------------------RTKN------------------------
------------------------------------------------------------
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--------------------------------------------------

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----------------------MSC-RLQSSS-------TSYGG-GFGGGSCQL------
-----------------GG--------------GRSFSTCSTRFASGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
----GGGFGGSYGGGSFG-----GFG--------------------------------DF
GSGDGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQKQSPAS--
---PERDYSPYYKTIDELRAKILAATTENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFGKQV-AGQVTVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFQSK
----------------SAELN-KEVASNTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSST-T----------------SNV----------
-------S----------GSG------------------SP---------SSSSPRRVS-
------D-VRRF------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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----------------------MSS-RLQSSS-------ASYGG-GFGAGSCQL------
-----------------GG--------------GRSISTCSTRVVSGGSAGGYG------
------------SG------I-SCGFGGGAGSGFVGGFGS------GFGG----SFGGGF
GGGFGGSYGVGFNGG--------------------------------------------F
GGGDGSLLSGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPTS--
---PERDYSHYYKIIEELRDKILAATIDNN------------RVLLEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSKQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHSK
----------------SVELN-KQVTSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSVAETECRYALQLQQIQGLISGI-EQQLSDLRSEIECQ--NQEYKVL
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSGGGNSGSASITVSTR----------
-------R------TS--------------------------------------ETRTS-
-------ETRKA------------------------------------------------
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---------------------------MSRS-------SRVSS---S-------RAGGSS
---------------SVRVSVGGSSF-SSGSRCGLGGGS----ARGFRGGA-S-----S-
----------------------YGLGEG------SG-------------------FGGGF
GSCSVG--GGFGGSSG-----SVAGFGVDSG--FGGGS----------------GLG---
---------------------------GASRG----FYSYGGG-------MS-----G--
GFGNGGLFSGGEKQTMQNLNDRLASYLDKVRALEEANTDLE---NKIKEWYDRFGSGSGD
AGSG-RDYSKYYPIIEDLRNQIITATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLRQTVEADVNGLRKVLDDLTMTRSDLETQIESLTEELAYLKKNHQE----
-EMKSMQGTS-GGDVTVEMNATPGTDLTKLLNDMRARYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--TSSAKSEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYMAQLSEIQLKISSL-EEQICQTRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGAS-GFGGG-DFRNSGLRNT--------G-----
------------S-RDL-------------------------------------------
I-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
S----SSQGRDP---SK----T-----------------RVTK-----------------
---------------TIVEEVVDGKVVSSQVSNV----SEVKI---------K-------
------------------------------------------------------------
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--------------------------------------------------

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--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGAGFGAGL
GAGL-G-------G---------GFGGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQS-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRTEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QGSSSFSQGQSS-
------SN----------------------------------------------------
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--------------------------------------------------

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----------------------LRRNAMSCS-------SRMPS---S-------RAGGSS
---------------SVRVSAGGSSF-SSGSRIGLGGGS----ARSFRGGA-G-----S-
----------------------YGLSGGTSGG-----------------------FGGGF
GSCSIG--GGFGGASG-----SGIGFGGGLS--FGGGS----------------S-----
---------FGGGSGFGR---GAGYGGGASGG----FYSYGGG-------VGGGVG-G--
GLGDGGLFSGGEKQAMQNLNDRLANYLDKVRALEEANVDLE---NKIKQWYEKFGPGSRD
GGAG-RDYSKYYPVIDDLKNQIITATTENA------------GIILQIDNARL-AADDFR
L-KY-ENELHLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKTMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEANYVVQLSQIQMQISSL-EEQVCQIRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-GFGGS-DYRSSGSRNM--------G-----
------------S-RNM----G--------------------SR-DS------------S
V-----------------------------------------------------------
---------------------------------------------------SDGSRS-GT
C-----VQGRDP---SK----S-----------------RVTK-----------------
---------------TIVEEVVDGKVISSQVSNV----SEVKL---------K-------
------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SIPGGSHAGGA----FGNAACVGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTSNANV
ILL-------AADDFRLKYENELTLHKICRGRHQRLRRVLDELTLCKTDQELQYESLKVG
GLYLYHACASLQ----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISHDAGAATSARSQLTEMRRTLQ
TLEIQLQSQLAT----VGDSEGQP------------------------------------
------------------G----SCDSRN----SCSKSKAFGSGSSGDLPK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKITNGKT--EKRVPF---------

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-------------------------------------------------M-----SSRLS
SCSGG--SASS--TGILRALCLGLECCGHFWGIGKVAS-PWLGRQ---------LI----
----GQEN--------------------QQREPILSAGSPFMAMRRIMEPPASLLDNVHA
LEEANV-----QKGWLRILGP-GC------------------------LIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KRSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRSISTCSSRFVSGGSTGGYG------
------------GG------V-SCGFGGGAGSGFGAGFGG------GF------------
GGSFGGGFGGGVAGGF-------GFG--------------------------------DF
GGGDGGLLAGNEKITMQNLNDRLASYLEKVRALEEANTDLE---VKIRDWYQKQSPSS--
---PERDYSPYFKTIEELRDKIQAANIENN------------RVVLQIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAFLKKNHEE----
-EMKEFSNRV-VGQVNVEMDATPGVDLTRVLAEMREQYEAMAEK-NRREAE---EWFNKK
----------------IEELN-KEVISSTAL--IQTSKTEITELRRTLQ---GLEIELQS
QLSTK---AGLENSLAETECRYALQLQQIQGLIGSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSNL-AGGGGPSN----------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRVG--------SVRLSSG---G-SGLGAGNTCGV-PGIGNGF-SCAFGGSSSAGSY
SGG----------LG----SGSVPCSTFTSNEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIITATTSNANI
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEVQLETLTEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTMQ
TLEIELQSLLAT----KQSLECSLVETEGNYCTQLAQIQAQIGALEEQLHQVRT------
------------------------------------------------------------
--------------------------------------------------

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-------------------------------------------------M-----SLQFS
NGSRHVCLRSG--AGSVRPLNG---G-AGFAGSSACGG-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCCGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVELA
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDSGAATSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSPGNSSK-DLSKTTLV
KTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGV-G-GFGGGSLYG------
---------------G-GG--------------SRSISVSSSRFVSSGSGGGFG------
------------GG------AG-----SGLGGGFGG-------------G-LG-------
-GGLGGGFGGGFAGSFGG-----GFG--------------------------------DF
GGGNGGLLAGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIHDWYKKQSPSS--
---PERDYSPYFKTMEELRDKIRAAAIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTVQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGLIGGL-ETQLSELRSEMECQ--NQEYKIL
---------------------LEGQDARM-AGIGTREASL---GGG-G------------
--------------GKVRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----AGL
GG--------GLGGGFGG-----GFGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----AGL
GG--------GLGGGLGG-----GFGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
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--------------------------MTATIRQFTSS-SSIKG--------SSGLG----
----A-----------------ARP-----------------------------------
------------------------------------------------------------
------------APPAGCLAAWSSCYSFGSGSG---------------------------
---------------YGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVP-----NTELE---VKIRDWYQRQAPGP--
---A-HDYSQYYRTIQELQNKILTATVDNA------------NILQQIDNAHL-AAADFR
P-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMHIENLKEELAYLKKNHE-----
-EVRWLGQKV-GGEINVEMDAAPGVDLSHILNEMRDQYEKMAEK-NHKVAE---DWFFSK
----------------TEELN-CKVATNSEL--VQSGKSEILELRRTMQ---ALEIELQS
QLSMK---ASLEGNLVETGNRYCLQLSQIQGLIGSM-EEQLAQLCCDMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRHLLEGEDAHLTQYKK--------------------------
E-----HKHLPVTTRQVCSI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
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------------------------MAPCRYG----G------------------ALGI--
--------------NFGG-----GFGGV--------------------------------
---DGGLLAGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPSE--
---I-KDYSPYFRTIEELKSKIITATMENA------------QSILQIDNARL-AADDFR
S-KY-EHELCLRQTVEADINGLRRVLDELTMTRSDLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDISVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRREAE---AWFLRK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHISGGQSYSSRE--------V--FS--SSSS--
----------SSTSRQPRPIL---KE------------QSS---------ASFSQVQSS-
------RN----------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRTCPRTT--AGSLRLSA----GGASFGAGNACGV-PGIGSNF-SCAFGSSSL----
----GANAG-----------GSNSCASFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIAATTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MSYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDLKVHLEKEIETYCLLIGGDDGACKSGSYKSKDYGSGNMGSQLK-DPIKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQGN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MSTTTVRQYSSS-SSLKG--------LGGLG----
----G-----------------GCS-RLSCVR----------------GGGYRAP-----
---------------SVH------------GGSSSYSV-SS-RIV-----SGLG------
--------SGYG-------GSYCSSVGGGLGAAFGG--------------SYGAGFGSGF
GA------------GFGS-----GFGGG------------------------------FG
GGD--GILPAGEKETMQNLNDRLAAYLDKVRALEDANTDLE---VKIREWYKKQGPGP--
---D-RDYSPYYRTIEELRSKILAATVENA------------NIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGEISVEMDAAPGIDLTKILTDMREQYETLAEK-NRRDAE---QWFFSK
----------------TEELN-REVAINTEQ--LQSGKTEITELRRTIQ---SLEIDLQS
QLSTK---AALEGTLADTENRYGAQLAQLQGLITSV-EEQLGELRCDMERQ--NHEYRVL
LDVKCRLEQEIA----TYRRLLEGEDAHISSQYSSAMSS--------------------H
S-----GRDGMTSSRQVRTI----VE------------EVQDG--KVVSSREQVA--LT-
--------------------------------TR--------------------------
------------------------------------------------------------
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-------------------------------------MQIESLNEELAYMRKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSLK---------------GS-
CGIGG-----------------GSG-RISSVL---------------TAGSCRAP-----
---------------SAYG---------------GLSV-TSSRFSSGGA-CGIG------
--------GGYGGGF----SS--SSFGGALGSGFGG--------------GYGGGLGAGF
GG----GFGGGYGGGLGG-----GFGGG------------------------------L-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARTDLEMQIESLKEELVYMRKNHEE----
-EMNSLRSQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKIAEK-NRKDAE---EWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHVLFCLHSLS---------SS--FSSGSQSHR-
--------EGTSTSRQIRT-K---VV------------DVHDG--KVV------S-----
---------SHEQ---------------V--LRSKN------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLVQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKATKV----------------------

------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSSF-SCALGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KRSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQSSS-------TSYGG-GFGGGSCQL------
-----------------GG--------------GRSISTCSSRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
--------GGGFGGSFGG-----GFG--------------------------------DF
GG-EGSLISGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPTS--
---PERDYSHYYKTIEELREKILAATIGNN------------RVLLEIDNARL-AADDFR
L-KY-ENELTMRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGKVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFQSK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQELITSL-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-SGFSSGGKFSVGGVLGS-------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSSRFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIRD-----------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLG--------SVRLSSA---G-GALGAGSTCGV-PGIGSGF-SCAFGASSASGGL
--------------------GSASCGAFTTNEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-LYFPIIEDLRTQIISATAHNANI
VLQNDNARLTA-DDFRMKYENELALHQSVEADINGLRRVLDELTLCRTDLEVQLETLSEE
LAYLKK--NHAE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLAETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCRLIDGDEGSCVKS----K--GQGEPRNQTK-ESSKTAIV
KTVVEELDPRGKVLSSRIHTLEEKSTKVTKNE-----QRVPS--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLG------
------------S-ALGS-NSYSSCYSFGTGS----------------------------
--------------GYGG-----NFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSAYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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--------------------VD----------------------LSSNTMS---------
-----------------------------LSVRTSGLPRRLSS---Q-S----GTSGR--
---------------VWGMSAS--SA-GGG-----YGGS----AFGLGS---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------GSCA---GGLGTAYGGALG-----------------------------
---------------------------GGFGGLVVGF---GASPG----G--GSL--GVL
SSNDGGLLSRSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGSGTVD
PGSQ-NDYSKYYPLIEDLRNKIISASIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALRQNVEADINGLRRVLDELTLARAD-EMQIENLKEELAYLRKNHEE----
-ELQSFRADG-PGQVSVEMDAAPGVDLTRLLNDMRAQYEAIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAFQ---NLEIELQS
QLAMK---KSLEDSLAETEGDYCGQLSQVQQLIGSL-EEQLLQVRADAERQ--NADHRRL
LDVKHRLELEIE----TYRRLLDGEAQGDVLDEIT---SVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TIVQEVLNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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---------------------------MSCS-------AWSGS---C-------SSR---
---------------VSSSVTGGNSF-SSRSRCGVGGGS----AQGFQGGASS-----S-
----------------------CGLSGGSKGGFGSG-------------------GEWGF
RSCSVR--GGFGAASG-----FGSG-----------------------------------
---------FDGGSGFGG---GSGFSSGTSGG----FYSAGGG-------IGGGLG-G--
GGSDGGLFSGSEKQTMQNLNDRLANYLNKVRALEEANTDLE---IKIKEWYAKHGRGFRD
GGSG-RDYSKYHSIIEDLKNQIITATVENA------------RMTLQIDNARL-AAEDFR
L-KY-ENELCLWQSVEADINGQRKVLDGLTMTRSDLEMQIEGLTEELVYLRKNHEE----
-EMKCMQGTS-RGDVTVEMNAAPGIDLTKLLNDMRAQYEELAAQ-NRQEAE---EQFHKQ
----------------SASLQ-AQISMDAGA--ASSAKSEVTELRRTVQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYMARLSEIQVQISCL-EEQICQIRGETECQ--NAEYSRL
LDIKTRLEMEIE----TYRRLLDGEGGRH-------DYRSSGSRD---------------
-----------------------------------------------------------V
A-----------------------------------------------------------
---------------------------------------------------SCDSRS-GS
C----SGQGRDPNK-------T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQISNI----SEVKIQ----------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRSCPRPTT--GSLRLSGG---G-ASFGAGNACGI-PGIGSGF-SCAFGSS-TSGGN
A------------------GGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANSDLEQKIKGWYEQFGP-GSCRGLDHD---YS-RYFPIIDDLKAQIIAATTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGEDGACKSGGYKSKDYGSGNLGNQVK-DTAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------G-SSR------------------TSCRLS-----
---------------GSLGG----------GSCRL-------GSA-----SALG------
------------S-ALGS-SSYSSCYSFGAGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSPYYQTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETESRYCVQLSQIQGLISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTH---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRSCSRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSGF-SCAFGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIVTSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
ILLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------SGYGG---------------LSV-SSSRYSSGGA-CGLG------
--------GGYGGGF----SS--SSFGGALGSGFGG--------------GYGGGFG---
-------------GGFGG-----GFGGG------------------------------F-
GGADGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPSE--
---V-KDYSPYFRTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYMKKNHEE----
-EMLALRGQT-GGDINVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVAELRRVFQ---SLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHYQ-SQH-SSGQS-Y-SSREV--FTSSSS----
----------SSSGHQTRPIL---KE---------------------QGSSSFSQSQSS-
------KH----------------------------------------------------
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--------------------------------------------------

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--------------------MFCSAQRGSCS-------SQVSS---S-------SSGA-V
---------------GSRVYDAGYTF-SSGSSCGLGGGS----SWGFQGSS-S-----S-
----------------------CGLSGVSKGGFGSG-------------------IGGGF
GGCSVR--GGLVGGSG-----------------FGGGS----------------GFHGGS
G--------FGGGSSFGG---GSGFGGNSSAG----FSSYGG--S-----LGGGLG-G-I
GGSEGGLLSGSEKQTMQNLNDRLATYLDKVRALEEANTDLE---TKIKEWYDKHGSG--K
GESG-RDYSKYWPIIEDLKNQVISATTENA------------RMSLQIDNARL-AVDDFR
V-KY-EHELCLRESIEADINGLRKVLDDLTMTRSDLEMQIEYYTKELVLLRKNHEE----
-EMKCMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEALAEQ-NRQEAE---KQFNER
----------------SASLQ-AQISTDAGE--ANSAKNEVMELRRSVQ---ALEIELQT
QLALK---CSLEGTLADTEAGYMSRLSGIQTQISSL-EEQLSQIRGETQCQ--NAEYECL
LNIKTRLEEEIE----TYRRLLNGEGGGC-------DYRNLVSRH---------------
-----------------------------------------------------------V
A-----------------------------------------------------------
---------------------------------------------------LDDSRS-GS
C----SGQGKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGVVVSSQVSNI----SEVRIK----------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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---------------------------MTTYTVQNSF-ASGAG----------GLGAA--
GS--------------------GSS-RLSSVR-------VGG---SYRTPSIHG------
---------------G-SG--------------GRGVSIST-KYVSSVG-GGYG------
------------GG------S-CAGFGGGYGGGY---------------GGFGGGAVCGL
G------------GG----------------A-----------------GFGGGFDAICA
FGGGDGLLSGNEKITMQNLNDRLATYLQKVRALEDANAELE---VKIRDWYQKEAPSS--
---PARDYSNYYKIIEDLQDKILAATIDNS------------RVVLEIDNARL-AADDFR
L-KH-ENELFLRQSVESDINGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEE----
-EMKEYSNQL-SGKVSVEMDAAPGIDLTRILSEMREQYEALAEK-YRKDAE---AWFLTQ
----------------TTELN-HEVATHTEQ--IQSSKSEITELRRTMQ---SLEIELQS
QISMK---AGLEANLRDTEGRYCAQLAQIQNLITSV-EEQLSEIRCDMERQ--NQEYRML
MDIKSRLEQEIA----TYRQLLETQDSQM-SGVNPKDASAAGRARGGTED----------
-------EGRSSSTRDRRHQ----------------------------------------
------------------------------------------------------------
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-M--------------------ALS-VRSSVGPRQFSSRSSLGG-GSLRLSGN----ST-
--------------GGGFGGSGLGFGGGSAGGFGA-------------------------
------------ASVLGSGSGFSGGFGSSVGSGFGGGF------ASGSGGGYGSGSGGGF
GGGFGSGFGSGSGIIFGG-----GFGSGAAPG------------------LGGGFG--IG
GGGDGGLLSGSKKETMQNLNDRLAAYLDKVRSLEDANTELE---RKIREWYEKNGPGAAV
PGSG-NDYSKYYPIIEDLRNKIINATIDNA------------RIILQVDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTRADLEMQIESLNEELAYLKKNHEE----
-ELQGLQSSA-VGQVSVEMDAAPGIDLTKLLNDMRGQYEVIAEQ-NRKEAE---AWFNEK
----------------VITSH-MENSVQ-----------HSGELKREISTNTEHQLLLCI
FPTQK---KSLEDTLAETEGGYCAQLSQMQLQIGNL-ESQLLQVRADMERQ--SAEYQQL
LDIKSRLEMEIE----TYRRLLDGEFVSGGQ-GVVFESSSL----------TG-S-KSQT
QSLD--SSQDPTKTRKIKTIVE----------------EVVDG--KVVASHVKEVEEK--
----------------------------I-------------------------------
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---------------------------MSCSRSSS---SCLR----GGSGG---------
----S---------------------QHGSASAHRYTASRA-GG-RPAGGSCS-GGSSRS
----------------------------S---CGA---TGFGRMR-RSSYGGGMSSG--M
GGSSYA--GGWSAGTYGGTMR------CGG---MGGGFGA---GGS----GFGAGYGGGF
G---SGSAGFSAGSFGGG-----GFGG---------------------------------
--ENMGILSNNEKLTMQNLNDRLASYLDKVRSLERENARLE---QLIREWYQKQGPTG--
---R-KDYSHYYTTIEDLQNQILTAAVETN------------KILLDLDNTRM-TAEDFR
T-KY-ETEYGLRQNVEADINTLRPLLDSLTLSRTDLEMQFESLKEEMINLKKDHEE----
-DMKSLQTQS-SGDVNVEVNAAPGEDLLKKLNDMRQEYEQIIQK-NREEVE---SWYESK
----------------MEEVS-QQVHSSGQE--LESSNQQISVLRRDYQ---SLEIELQS
ELSRV---GALQSNLEDTERRYNMQLQQIQGMIGPL-EEELASIRCEMESQ--NEEYKML
LGIKTRLEQEIA----QYRALLNEGQHGIST-----------------------------
-------------------------SQGGA-GGGSSGGHGHGG--TSGSSAQGGSGGGS-
--------------SWCSRGRSSGG---SGGKTSGGGG---------G---G--------
-CGKA---SGGGGGSG-GGEGGK----------GCLSRSSS---------S-HSQSG---
--------SCE------------SPG----DAENL----------------------KLC
L--------------------------E-G-N---K-----------------TLERG--
-----------------------------------------ATMEE--------------
--------------------------------------------------------VSE-
--AIK-----------------------TLRSRK----ASGPDS----------------
-----------------IS-ND--------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MATYSFRQTTS-----S----------VAGGP--
-C-------------------------GRSLR-------LGGGS--FRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSGLGSGLG------
------------GG------YGGA-FSSS------------------------------F
SAGFGGGYG----GGLGS------------------------------------------
---GDGLLSGNEKTTMQNLNDRLASYLDKVRALEEANSDLE---TKIREWYLKQGP-G--
---PARDYSPYYKAIEDLRDQILAATIDNS------------KVVLQIDNARL-AADDFK
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLELQIENLKEELAYLKKNHEE----
-EMSALGGQV-AGQVSVEVDSAPGIDLSKILADMRDQYEHMAEK-NRKDAE---AWFHSK
----------------TEELN-REVAVNTEQ--LQSSKSEVTDLRRTLQ---GLEIELQS
QLSMK---GALESTLADTEGRYGAQLAQIQDMIGSI-EAQLAELRADMERQ--NSEYKML
MDIKTRLEQEIA----TYRQLLEGQESQL-FGSLSGSPDKRD------------------
---------KPADGK---------------------------------------------
------------------------------------------------------------
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-------------------MSLRLSGGSRRSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEVKIKGWYDKFGP-GSCRGLDHD---YS-RYFPIIEELKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLSETEGNYCSQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDEGACKSGGYKSKDFGAGSMGNQIK-DPIKAIVV
KKVLEEVDQRSKILTTRLHSLEDKPQSN----------------------

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-------------------------------------------------M-----SLRFS
SGSRHICLRSG--SGSVRPSNG---G-TGFAGSNACGS-SVAGSGF-SCALGGGLG----
----SVPGGNHAGGV----LGSSACAGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDRD---YS-GYHLTIEDLKNKIISSTTANANV
ILQIDNARLAA-DDFRLKYENELALHQNTEADINGLRRVLDELTLCRTDQELRYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSATLQQQISDDAGAATSARNELTEMKRSLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKATLV
KTVVEEIDQRGKVLSSRVQSIEEKRSKMANGKT--EQRVSF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRASS---S-------RAGGSS
---------------SARVSAGGSSF-SSGSRCGLGGSS----AQGFRGGA-S-----S-
----------------------CSLSGGSSGAFGGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGTGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSRFSSGATGG----FYSYGGG-------M----G-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEDLRNQIIAATVENA------------GIILHIDNARL-AADDFR
L-KY-ENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEE----
-EMKNMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---ERFNKQ
----------------SASLQ-AQISTDAGA--ATSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQISAL-EEEICQIWGETKCQ--NAEYKQL
LDIKTRLEVEIE----TYRRLLDGEGGGS-------SFAEFGGRNS--------G-----
------------S-VNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIVEELVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHAVEEKATKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MSTTVRQYSSS-TSLKG--------FGSLG----
----G-----------------GSS-RVSSVR--------------VGPGGYRAP-----
---------------SVH------------GGSGSYSV-SS-RVV-----SGLG------
--------GAFG-------GSYCSSAGGALGAGFGG--------------SYGAGFGA--
-----------------------GFGAG------------------------------FG
GGD--GILPAGEKETMQNLNDRLAAYLDKVRALEEANTDLE---VKIREWYKKQGPGP--
---D-RDYSPYYRTIEELRNKILVTTVENS------------NLLLQIDNARL-TADDFR
T-KF-ETEQALRVNVEADINGLRRVLDELTLSRADLEMQIENLKEELAYLKKNHEE----
-EMTALRGQV-GGEISVEMDAAPGIDLTKILADMREQYETLAEK-NRRDAE---QWFFTK
----------------TEELN-REVAINTEQ--LQSGKTEITELRRTIQ---SLEIDLQS
QLSTK---AALEGTLADTEARYGTQLAQLQMLITGV-EEQLAELRCDMERQ--NHEYRVL
LDVKCRLEQEIA----TYRRLLEGEDAHHISAQQPSDGA--------------------G
S-----AHELMTSSRQVRTI----VE------------EVQDG--KVVSSREQVA--LT-
--------------------------------TR--------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----FGNAACVGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLEHD---YS-RYHLTIEDLKNKIISSTTANANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCKTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISHDAGAATSARSQLTEMRRTLQ
TLEIQLQSQLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCHLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKITNGKT--EKRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAMS----------SYGGM--
-G-------------------------GGPVR-------FGSGG-VFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRIVSS-SSGG--------
------------------------------------------------------------
-----------YVGGRGG-----SFSG----A--------------------------L-
-TVTDGLLGGNEKITMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PFRDYSQYFKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIENLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSTPGIDLAKILSEMRSQYEAMAEK-NRKDAE---AWYLTQ
----------------IDELN-TQVAVHTTQ--IQINKTEVTELRRKVQ---DLEIELQS
QLSMK---AALEGTVAEIEARYGAQLSHIQGVISSI-EVQLSNVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NSLSIAKA---L------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------MPYSVQKSS----LWQFS------------
------------------------------------------------------------
---------------------SGQGRGGTAG-----------------------------
-----------------K---KYGLS-GSLGG---SFSSTFGGY-------------N-F
GGGENGLLSGNEKGTMQNLNDRLAVYLDQVRALEQANNELE---SKIKEWYKKFGPGSTS
HGEN-RDYSEYYQIIKELKHKILDSTISNA------------DIMLQTDNVRL-AADDFK
L-KY-ETELALRQSVESDINGLRRVLDDLTLAKTDLEIQIETLSEEVAYLKKNHAE----
-EMKGLQKVA-SSDVNVEMNAAPGTDLTKLLNDMRAQYEALAEQ-NRKDVE---TWFNSK
----------------SELLQ-QQISLATDE--SNSAKTEISELKRTSQ---TLEIELQS
ALALK---KSLEGSLSETEAGYSTQLSQTQNQISSL-EAQLIQIRDEAESQ--STEYKQL
LDIKTRLENEIE----TYRRLLDEEGGMEGIPILSAFYRE----N---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
Q----GSKKLKPTK-------T-----------------F--------------------
------------LYKTIVEELVDGIVVSSKIKDVHQRSA---------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGAGNTCGV-PGNASGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPVIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHDE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKN--EQRVSS---------

------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSSF-SCALGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQSSS-------ASYGG-GFGAGSCQL------
-----------------GG--------------GRSISTCSTRFVSGGSAGGFG------
------------GG------V-SCGAGSGYGGG----------------------FGGSF
GGGFGGGFGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQTPTS--
---PERDYSPYFKTIDELREKILAATIDNN------------RIILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQM-AGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---AWFHSK
----------------SAELN-KEVSSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGVLTVA-GSMCNPG-QVTYPCGLTFL-----------
-------P------AQYSLGSY----------------ES-------Q-----MLRTVQ-
-------ASSKCS---------------IN------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------IISATTSNASV
VLQNDNARLTA-DDFRLKYETELALHQSVEADINGLKRVLDELTLCRTDLEIQAETLNEE
LTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--WFNEKSATLQQQISDDAGATTSARSELTEMKRTVQ
TLEIELQSLLAT----KHSLECSLTETEGNYCVQLSQIQAQIGALEEQLQQVRTETEGQK
LEYEHLLDIKVYLEKEIATYCSLIDGE--DCYKS---KGSYVPGGPGNQIK-DSSKTTLV
KTVVEEIDPRGKVVSSRVHSVEEKSSKISAIKT--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSQRYGS-SKNFSS---SRS----GGG----
---------------------GSSSIRISSSRGS-------------SYGGGS-----V-
GGRFISTG---SS--S--------YGSCSRGGYGGG-------------------SLGGF
GG-------GFGGGSC---GG----------GSFGGGYGG----GS----CGGGSFGGGY
GGGSFGGGSFG------G----GSFGGGSF---------------------GGGLLGGSF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVKALEDSNYELE---QKIKEWYEKNGNS--R
QREP-RDYSNYYDTIADLKNQILNLTNDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDDLTLAKTDLEMQLEGLSEEMAFLKKNHEE----
-EMKDLQNVT-TGDVNVEMNAAPGVDLTQYLNRMRNEYEQLAEQ-NRRDAE---AWFNEK
----------------SKELT-TEIDSNVEQ--MSSHKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCSQLSQIQVQITAL-EEQLQQIRAETECQ--NSEYQML
LDIKIRLENEIQ----TYRSLLEEGGSGGSYGGG--------------------------
-----------------------S---RGGSSGGGYGGSSGG-G-GY-------------
-------------------------------GGSSGGGQGGGSSSGGYGGSS--------
-------------------GGSG----------EFKSS--GSRG---GSSGRQGGSS-GS
GGESPSKSSSGTRF----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AAFAGSSACGS-SVIGSEF-SCALGGGLG----
----SAPGGSHAGGV----FGNAACVGFVGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-IYHLTIEDLKNKIISSTTANANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCKTDQELQYESLNEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQITHDAGAATSAQSQLTEMRRTLQ
TLEIQLQSQLAT----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNLPK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKITNGKT--EKRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LCIDTMSLSVYNSGASRQTSS---R-S----GVGGR--
---------------RLSHLSS-------SSSGGGFG---------SGA---C-----S-
GGSFSA-A---SM--FGSS---CGFGSSSG------------------------------
------------NAFG---GGLGSGYGAGLGSGYAVG-----------------------
------------------------LGSGYGSGLGNSY---GGGLG------SGSM--GIS
CSNDGGLLSGSEKETMQNLNDRLASYLTKVRALEEANTELE---NKIRDWYETRIT--GD
SVSR-NEYEKYYPLIEDLRNKIISATIENA------------RLILQIDNARL-AADDFR
M-KY-ENEQALRQNVEADINGLRRVLDELTLARTDLEMQIEGLMEELAYLKKNHEE----
-ELQAIQAGG-PGHVSVEMDAAPGINLTKLLNDMRGQYETIAEQ-NRKEAE---AWFIEK
----------------SGELK-KEISHNTEQ--LQTSKSEITDLKRTLQ---SLEIELQA
QLAMK---KSFEDTLAETEGGYCNQLSQIQFQIGSL-EAQLSQVRCDMERQ--NAEYEQL
LNIKTRLEMEIE----TYRQLLEGELEGNDAVENL---NVPESNSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPAR-------T-----------------RKIK-----------------
---------------TIVQEVVDGKVVASEVREIEEEI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGG---
--------------------GGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLGGF
GGGSFG--GSYGSSSF---GG---------------------------------GYGGSF
GGGSFGGGS------FGG----GGFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSFGG-GYGGGSSGGG-------------------
----------------YGGG----------SSGGGFGGGSSGGG-Y-------GGGS---
----SGGG---SSGGGSSGGGYGGGSSSGGHGSSSGGGYGGGSSGGG-------------
---------------------GG-------------SSGGGGYGGGSSSGGHKSSSS-GS
VGE---SSSKGPRSAETSWGNQ-----------------N--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LSVRTSGGSRPFSS---R-S----GFGGG--
---------------SLRMSNS-------S-GGGGYGGS----GLGFGG---G-----S-
GGGFGA-A---SL--ASSS----GFGGGFGSSSVAG-------------------FGSNL
-----S--SGFGGSYG---GGLGGSYGSGLGSGFGGGL----------------G-----
-------------SGFGSS-SGAAFGSGFGGGLGTG--------------FGGGF--GPA
GAGDGGLLSGSKKETMQNLNDRLAAYLDKVRSLEEANTELE---SKIREWYEKNGPGTGT
PGSG-NDYSKFYPLIEDLRNKIINATIDNA------------RIILQVDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTMTRADLEMQIESLNEELAYLKKNHEE----
-ELQGIQSSE-FGQVSVEMDAAPGTDLTKLLNDMRGQYEVIAEQ-NRKEAE---AWFNEK
----------------SGELK-REISTNTEQ--LQSGKSEITDLKRTLQ---SLEIELQS
QLAMK---KSLEDTLAETEGGYCAQLSHIQMQIGNL-ESQLFQVRADMERQ--NAEYQQL
LDIKTRLEMEIE----TYRRLLDGEFVGGGGGGGGGGGGGGGGGGG--------------
----------------------------------------GGGG-GG------------G
GG------------GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG------G-
-GGGGGGGGGGGGGGG-G-GGGG----------G---GGGGGGGGGGGGGGGGGGGG-GG
G----GGGGGGKKK-------K-----------------KKVK-----------------
---------------W--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----ALRCP
SGSRHRGLYSG--AGSIRPASR---G-TGLVSSGSCGS-AVFGSPF-SCAFGGGLG----
----GVPGGNPGGGG----SG-HACTSFAGSEGGLLSGSEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKSWYDTYGP-GSCRGLDQD---YS-SLHLTIEDLKAKIISSTAANARV
ILQIDNARLAA-DDFRLKYENEVTLHQNVEADINGLRRVLDELTLCKTDQELQYESLSEE
ASYLKR--NHEE----------------------DMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAQQNHSDAEA--WFSEKSASLQQQMSHDAGKATRARTELTELKRTLQ
TQEIELRSLLAT----KHSLECSLSETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYRRLIDGDEG----SCSKSEGFGSGSSGHSPK-DLPKTTLV
KTVVEELDQGGNVLSSRIYSIEEKTLTLINKT---DQRVPF---------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGPGNSCGI-SGIGSGF-SCAFGGS-SSGGN
T------------------GGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYLPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGAYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTALLQ-SS-S---S----------TFGGG--
SA------------------------RGGSLR-------AGG-G-GFGGGSLCG------
---------------GAAG--------------SRSISASSARFVS-GSAGGYG------
------------GG------M-SCG-----------------------------------
--GFGGGFGGGLGGGFGG-----GFG--------------------------------DF
GGGDGGLLGGNEKITMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQRQGPAS--
---PERDYSRYFKEIEELRDKIMAGTIDNS------------RVILEIDNARL-AADDFR
L-KY-EHELNLRQTVEADINGLRRVLDELTLARADLEMQIEGLNEELAFLRKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYATQLQQIQGLIGGL-EEQLAQLRCEMEAQ--SQEYNML
LDIKTRLEQEIA----TYRSLLEGQDAKY-GTGTVPLLSVAA----LGS-----------
-----------GGSSNFRIKVE----------------ESVDG--KV----------VS-
------S--HKRD---------------L-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRISS---S-------RAGGSS
---------------SVRVSAGGSSF-SSGSRCGLGGGS----GRSFRGGA-G-----S-
----------------------CGLSGGSG----GG-------------------FGGGF
GSCSVG--GGLGGV-G-----YGAGFGGGSG--FGGGS----------------S-----
---------FGGGSGFGG---SSGFGGGASGG----FYSYGGG-------M----G-G--
GAGDGGLFSGGEKQTMQNLNDRLASYLDKVRALEEANADLE---NKIKEWYDKFGPGSRD
GGSG-RDYSKYYPIIEDLKNQIMTATVENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLRQSVEADINGLRRVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMRNMQDNS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQITTDAGA--ASSAKTEVTELKRTLQ---ALEIELQS
QLAMK---SSLERTLADTEAQYMSQLSEIQMHISSL-EEQICQIRGETECQ--NAEYAQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------YSGGSGSR----------------
---------------NM----G--------------------SR-G-------------S
G-----------------------------------------------------------
---------------------------------------------------SGDSRC-GS
G----SGQGRDP---SK----T-----------------RVTK-----------------
---------------TIVEEVVDGKVVSSQVSNV----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRKPGPRPTT--GSLRLSST---A-ASFGAGNACGI-PGIGSGF-SCAFGGS-SSGGN
A------------------GGSSLCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAGLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRALDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYENLAEQNRRDAED--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLAETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGEDGACKSGSFKSKDYGSGNVVTQVR-DPPKAIVV
KKVLEEVDQRSKMLTTRLHSLEERSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVCTSGLSRRSSS---Q-N----GAAGR--
---------------PWGASAS--SI-ACG-----YGGM----ASGFGV---G-----C-
GGLISA-A---SM--FGSS---SGFSGGSA------------------------------
-------------GSL---PGLATAYGGPLGGGLGGL-----------------------
-------------------------------GM--GI---GRSSG----G--GSL--CIL
SDNDGGLFSGSEKETMQNLNDRLASYLGKVRALEEANAELE---SKIREWYETRRT--GG
SGPQ-GDYSKYYPLIEDLKNKIISASVGNA------------QVLLQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRRVLDELTLARADLEAQTENLTEELAYMKKNHEE----
-ELQSFQAGG-PGEVSVEMDAAPGIDLTKVLNEMRAQYETMADQ-NRKDAE---AWFLEK
----------------SGELR-KEISSNTEQ--LQSSKSEITDLRRMVQ---NLEIELQS
QLAMK---KSLENSLAETEGGYCCQLSQVQQLIGNL-EEQLQQLRADAERQ--NADHQRL
LGVKARLEMEIE----TYRRLLDGEAHGDGFEESS---SLAVSKPQ--------S-----
---------------------------------------QAPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVQELEEAM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSTRFVSGGSAGGYG------
------------GG------V-TCGFGGGAGSGFGGGYGG--------------------
------GLGGGFGGGYAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYHKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGVPSSAGSVSPRSTSVTTT----------
-------S------SVS-ATTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MATTFLQ-T--S---S----------TFGSG--
ST------------------------RGGSLR-------VGG-G-SFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGVGFG------
------------GG------M-SCGFGGG----------------------FG-------
---------GG----FGG-----GFG--------------------------------DF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQSPAS--
---PDRDYSHYFKTMEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGLITGL-ETQLSELRCEMEAQ--NQEYNML
LDIKTRLEQEIS----TYRNLLEGQDAKM-AAIGVREASL---RGGS-------------
----------SGGGSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------S-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRNISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSVFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTTEELRDKITATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGGS------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSVRYSS--KQYSS---SRS----GGGGGG-
--------------------GGGSSLRVSSSKSS-------------HGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GY------------------------GGF
GGGSFG--GGFGGGS----------------------------------------YGGGY
GGGSYGGGSYGGG-SYGG----GSFGG-------GGY--------------GGGFG-GGY
GGDGGGLLSGNEKVTMQNLNDRLASYMDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYQTIEELKNQLLIFLHEFVYYKCCHDMKSNLNTFFLLYIQCL---CPAC
F-RY-ENEVALRQSVEADINGLRRVLDELTLSKADLEMQIESVTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGIDLTQKLNNMRSQYEQLSEK-NRKDIE---TWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQGQISVL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLEGEGGYVGNLQTRRVGRGGG------------------
--------------------------RGAVSGGGSYGGGRGGGG-SYG------------
--------------GGSSGGGSHGGSYGGGSSGGGGGSYGGGSSSGGG------------
---GSHGGSSGGGYGG-GSSSGG----------QS-----------GSGGGFK--SS-GS
GGD---QSSKGPRSAETSWGNL-----------------N--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGAGFGGGL
GGGL-G-------G---------GFGGV------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQS-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRNEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QGSSSFSQGQSS-
------SN----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------IIAATIDNA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQT-GGDVSVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSQL--VQSSRSEVTELRRTLQ---GLEIELQS
QLSMK---ASLEGSLEETKGRYCMQLSQIQGLIGNV-EEQLAQLRCEMEQQ--NQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSSSQH-SSGSGQYSSSRDA--YT-SSSSS--
----------SSTGRQTRPIL---KE---------------------QGSSSFGQSSK--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSLKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----AGL
GG--------GLGGGLGG-----GFGGG------------------------------F-
AA-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MATTTSIRQFSTS-GSVKG--------LCVPG----
----G-----------------GFS-RVSSIR--------------VGGA-CRAP-----
---------------SLLGA----------GTCGNMSM-ASSRFS-----AGLG------
--------GGYS-------G----GYTCSLGGGFGS------------------------
--------------SFG-------------------------------------------
--VADALLGGSEKETMQNLNDRLASYLDKVRALEEANADLE---VKIHDWYKKQGPGP--
---A-RDYSAYFKTIEDLRSKILAATIDNA------------NLVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKIAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLEGSLAETEARYGAQLAQLQGLISSI-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLAAQYSSS-L-------------------VSQ
P-----TREATVTTRQVRTI----ME------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RIQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRSISTCSSRFVSGGSAGGYG------
------------GG------M-SCGFGAGAGSGFGGGF----------------------
GGGFGGGLGGGFGGGFGA-----GFG--------------------------------DF
GGGDGGLLSGNEKLTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQSPSS--
---PERDYNHYYKTIEDLRDKILAATIDNN------------RVVLEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAFLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHSK
----------------SAELN-KEVSSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSLAEMECRYAMQLQQIQGLIGGI-EAQLSELRSEMECQ--NQEYRML
LDIKTRLEQEIA----TYRSLLEGQDARM-AGLPSSGGKETTRWESLS-V----------
-------S----CPLCFSGSTS----------------VT-------GTTASPPSRRIS-
--------DTRKP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMKS--------SCGIG----
----G-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------STYGG---------------MSV-TSSRFSSGAA-CGIG------
--------GGYSGGF----SS--SSF--------GG--------------GFGGGLGGGF
GGGLG------------G-----GFGGG------------------------------L-
---GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANSDLE---VKIRDWYQRQRPTE--
---I-KDYTPFFRTIEDLQSKIVRAKQENA------------QSVLQIDNARL-AANDFR
T-KY-DNETSLRQLVESDINNLRRVLDELTMSRADLEMQIESLREELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDVE---AWFQSK
----------------TEELN-QEVASNHEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCVQLSQIQGLIGSL-EEQLAQLRCEMEQQ--SQEYNIL
LDVKTRLEQEIA----TYRRLLDGENVHSSSSQH-SSGQSYSSG--EV--FS--------
-----------SSSRQPRSIL---KE------------QGS---------TSFSQSQSQ-
------SSGY--------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQYTSS-SSIK---------------SS-
GGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-SSTRYSSGGA-CGRG------
--------GGYGGGF----SSS-SSFAP--------------------------------
------------------------------------------------------------
--------GGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRLSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVSS-SRQVRT-K---VV------------DVHDG--KVV------S-----
---------THEQ---------------I--VRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGG----------GSCRL-------GSA-----SGLG------
------------S-GLGGSSGFSSCYSFGSGS----------------------------
--------------GYGG-----SFG----------------------------------
--AVDGLLGGGEKATMQNLNDRLASYLDKVRALEQANAELE---VKIRDWYQKQAPGP--
---V-RDYSPYYKTIEDLKNKILVASVDNA------------NVLLQIDNARL-AADDFR
T-KF-ETEQALRMSVESDINGLRRVLDELTLSRADLEMQIENLNEELAFLKKNHEE----
-EMNALRGQM-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLISSV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMKG--------SCGIGGS--
------------------------S-RV---------------------SSCRGP-----
---------------SAYGG---------------LSV-TSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGGY----------------------GGGLGAGF
GS------------GFGG-----GFGGG------------------------------F-
GG-GDGLLAGNEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFRTIEDLKNKILTATKENA------------QSVLQIDNARL-AADDFR
T-KF-EHEQALRMSVEADINGLRRVLDELTLARTDLEMQLEGLKEELAFLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQLAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCVQLSQIQGLIGGV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHISSGQAYSSRE--------V--FS--SSSS--
----------SSTSRQPRPIL---KE------------QSS---------ASFSQGQSS-
------RN----------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SGSRHIALRSA--AGSARAPST---G-AGFASSNVCGS-SPAGSGF-S--LGGGLG----
----SAASGSQASGI----LGNAASVGFAGSEGGLFSGNEKVTMQNLNDRLASYLESVRA
LEEANXXXXXXXXXXXXXXXX-XXXXXXXXX---XX-XXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX--XXXX----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--RFNEKSATLQQQISDDAGAATSARNELTEMKRSLQ
TLEIELQSLLAT----KHSLEGSLTETEGNYCAQLSQIQAQIGALEEQLHRVRTETEGQK
LEYEQLLDLKVHLEKEIETYCRLIDGDGS----SCSTPKGFGSGIPGDASK-DLSKTTLV
KTVVEEIDQRGKVLSSRVHSIEEKTSKMTNGKT--EQRIPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----GGL
GA--------GLGGGLGG-----GFGGG------------------------------F-
AG-SDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNVACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYRP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGAATSARSQLTEMRRTLQ
TLEIQLQSLTAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSSTS----------TLGLG--
-S-------------------------NNAAR-------FQRG---FRAPSIHG------
---------------G-SG--------------GLGVSVS--RFASSGLGGS--------
------------------------------------------------------------
-----------YGGGS---------SS----F----------------------------
WATADGLLAGNEKITMQNLNDRLASYLDKVRALEEANAGLE---VKIRDWHQKQGP-G--
---PARDYSAYMRTIQDLRDQILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EISALSGQV-GGQVSVEVDSAPGIDLAKILTDMRSQYEAMVEK-NRNDAE---AWFTSK
----------------TEELN-REVAGDKEQ--LQISKTEITDLRRTFQ---GLEIELQS
QLSMK---AALEGTLAETEARYGAQLSQIQVLISNI-EAQLSDIRADMERQ--NQEYLLL
MDIKSRLEQEIA----TYRSLLEGHDAQD-NIIPTTPK---AF-----------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-TLGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYYRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSAGGYG------
------------GG------V-SCGFGGGAGSGFGGGYGG------GL------------
GGGYGGGLGGGFGGGFAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYYKTIEELRDKILTATIENN------------RVILEIDNGRL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSSAGSVSPRSTSVTTT----------
-------S------SAS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLCFS
AASCR--LGSC--GGSARFSS----GGAGFWGSSA-----------------GGCG----
----GGLGG-----------GNTPCAAFTGNEHGLLSGNKKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-KYLPIIEDLQNQILSATTSNTNV
ALQNDNARLTA-DDFIL-----LALHQSVQADINGLHRVLDELSMCRTELETQLGTLSEE
LAYLKK--NHQE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEGLAEQNRRNAET--WFNEKSASLQQQISHDVGATTSARKELTEMXXXXX
XXXXXXXXXXXX----XXXXXXXXXXXX-XXXXXXXXXXXXX-XXXXXXXXXXX-X---X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXSKTSIV
KTVLEEVDPRGKGLSSRIHTMDDKSTRVN-IKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGG----------GSCRL-------ASA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SF-----------------------------------
----DGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSHYYKTIEELQNKILTASVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELVYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-HEVATNSEL--VQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTH----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MASTTSVRQFSTS-GSVKG--------LCAPG----
----M-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGNMSV-TSSRFS-----AGLG------
--------GGYG-------G----GYTCSLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGSEKETMQNLNDRLATYLDRVRALEEANADLE---VKIREWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------ASQ
P-----SREGMVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYHRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-------------------------MASTTICQYTTS-SSIKG--------SSSLG----
----G-----------------S-----STR------------------ASCWAP-----
---------------GSSFGS--------VSSSRL-------VG------GSLG------
--------GGYG------GSCYFGCLRSGMGD----------------------------
--------------SYGS-----SFG----------------------------------
--GVDGLMAGGEKATMQNLTDCLASYLDKVA--QEASTDLE---LKIRDWYQKQAPDP--
---A-KNYSGYHQTIEDLKNKILTATVDNA------------NILLQIDNARL-AAADFR
T-KY-ETELALRTSMDTDISGLHRT-----LSRTDLEMQIQNMKEELAYLRKNHEE----
-EMNSLRGQV-SGEINVEMDAAPGVDLSRTLAEMCDQYEKMVEK-TRKDAE---DWFFSK
----------------TEELN-QEVDTNSEL--LQSGKSEISELRRSVQ---ALDIELQS
QLSMT---ASLEGSLAETESCYCVQLSQIQGLSSSA--EELAQLHCEMERQ--NRLHKVL
LDVKTHLEQEIA----TYRLLLGREDAXXXX-----------------------------
------XXXXXVTAHQVHII----VE------------EVQDG--KVISSREQVH--QS-
--------------------------------PH--------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSV-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSSRFVSGGSAGGYG------
------------GG------V-SCGFGGGAGSGFGGGFGG------GVGG----SFGGSF
GGGFGGSFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNERLASYLDKVRALEEANTELE---VKIRDWYQKQAPTS--
---PERNYSHYYKTIEELREKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMRAQYETLAEK-NRRDAE---EWFQSK
----------------SAELT-KEVTSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENSVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKVL
LDIKTRLEQEIA----TYRSLLEGQDAKM-VGFASAGGSVSTSTNGSTVR----------
-------T------S---------------------------------------------
--------EVRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGG-
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLGGF
GGGSFR--GSYGSSSF---GG---------------------------------SYGGSF
GGGSFGGGSFGGG-SFGG----GGFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGEP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--ISSYKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSXXXX-------------------
----------------XXXG----------GS---SGGGSSGGG----------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------SSSKQYSSSRSGGG-GGGSSSI--R-ISSS
-------------------------RGSGYGVSSIGGGSSYGSCS-RGGFGSGSVRG--F
---------GGGGGGFGASSSFGSSFGGGG---FGGGSCG---GGSFGGGSFGG---GGF
GGGSYGGGSFGGGSFGGG-----GFGGGLGGG-----------------LGGGLGG--GF
GGGDGGLLTDESYWTSNELLKK-ASEIKEMKKQERCNLYLPRISKIQTCWTNS-------
---K-YNYLGIYRVT--NKAEILNLSTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVTLRQSVEADINGLRRVLDDLTLAKSDLEMQLESLNEELAFLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTEYLNRMRSEYEAMAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDTNVEQ--MSSHKSEITELKRSLQ---ALEIELQS
QLALK---QSLESSLAETEGRYCVQLSQIQAQITAL-EEQLQQIRAETECQ--NSEYQVL
LDIKIRLENEIQ----TYRSLLEEGGSNYLVSLSKK------------------------
--------------KNLGG--RLSSSGGGG-RGGGSGGGYGG------SSGGGGYG----
---------------GSSGGG-------GYGGSSGGGGY--GGSSGGG---G--------
-YGGS---SGGGGYGG-SSGGSG----------GFKSSGSR-GGSSGGQGG-ST------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------GSGGESSS--K-G--
-GS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
-------------------------------------------------M-----SLQFS
NGSRHVCLRSG--AGSVRPLNG---G-AGFAGSSACGG-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLA
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSPGNSSK-DLSKTTLV
KTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQYSS---SKS----GGGG---
--------------------GGGGSIKISSSKSS-------------HGGGYS-----S-
GGGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG--------------------GLG--
-G-------GYGGGSF---GG---GYGGG---SFGGGYG-------------GSSFG---
-GGSFGGGNFGGG--FGG----------------GGY--------------GGGFG-GGM
G--DGGLLSGNEKITMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKYGNR--G
QREP-RDYSKYYRTIEELKNQILNLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVDADINGLRRVLDELTLTKADLEMQIESLTEELAYLRKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------VTGLPLHEIDSNIEQ--MSSQKTEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISSL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGGYSKSPGFPKTQG-----------SAREC-----
------------SKGGYGG----------GSSGGGYGGGSSG-G-GY-------------
-----GG--------GSSGGGG--GGSYGGGSSGGGGSYGGGSSGGGYGGG---------
----SSGGGGGGSYGG-G-----------------------------SSGGGRKTSS-GS
TGE---SSSKGPRSGEPGWGNK-----------------NS-------------------
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--------------------------MTSYSYRQ----SSVSS----------SLGGL--
-G-------------------------GGSGR-------YGV---ALRAPSIHG------
---------------G-SG--------------GRGVSMSSARFVSS-SSGG--------
------------------------------------------------------------
-----------YGGGF---------VG----G--------------------------M-
-AGPDALLSGNEKVTMQNLNDRLASYLDKVRALEAANGDLE---VKIRDWYQKQGP-G--
---PSRDYSHYYQTIQDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQAMRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EVNALRSQV-GGQVNVEVDSVPGTDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------SEELT-REVAVHTEQ--LEAGKTEVTDLRRSMQ---SLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISSI-EAQLSDVRADTERQ--NLEYQQL
MGIKSRLEQEIA----TYRSLLEGQEAHY-NNLPGPKV---L------------------
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------------------------------------------------------------
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-----------------------------MSVRYSS-HKQYSS---SRS----GGG----
-------------------GGGGSSLRISSSKGS-------------LGGGFG-----S-
-GGFSG-G---SF--SRGSSSGGCFGGSSG-GFG--------------------------
--------GGYGGSSF---GG---GYGSS---SFGGGYG-------------GGSFG---
-GGSFGGGSYGGG-SFGG----GGF--------------------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYQTIEDLKNQILTLTTDNA------------NILLQIDNARL-AADDFR
M-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQGQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGRYAGEVPQ--PPAP-SIPLS--PSSSGGG-----
---------------SYGGG--RG----GGSSGGGYGGSSGG-G-GYG------GGS--S
SGGGYGG--------GSSSGGGHGGGSSGGG---HGGGYGGGSSSSG-------------
----GHGGS----YGG-G-SS----------------------GGGQSGGGGFKSSS-GS
AGE---SSSKGPR-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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----------------------MSC-RFQSSS-------MSYGG-GFGAGSCQL------
-----------------GG--------------GRNISSCSSRFVTGGSAGGYG------
------------GG------M-SCGFGGGAGGGFG-------------------------
-----GGFGGSYGGGFGG-----GFG--------------------------------DF
GGVDGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLE---VKIRDWHLKQSPAS--
---PERDYSAYYKTIEELRIKILEATTDNN------------RIVLEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFQAK
----------------SAELN-KEVSSNAEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFNSGGNNTTTSNGS-PS-----------
--------------SNSG---------------------R-------P-----DFRKY--
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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSSF-SCALGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KRSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTSIRQFTSS-SSIKG--------SSGLG----
----G-----------------S-----SSR------------------ISCQLS-----
---------------GSLGA----------GSCRL-------GSA-----GGLG------
--------SALG------GSSYSSCYSFGSGGG---------------------------
---------------YGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEADTELE---VKIHDWYQRQAPGP--
---A-RDYSQYYRIIEELQNKILTATVDNA------------NILLQIDNAHL-AAADFR
T-KF-ETEQALCLSVEAGINGPCRVLDELTLARADLEMHIENLKEELAYLKKNHE-----
-EMNAPRGQV-GGEINVEMGAAPGVDLSRILNEMREQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENRYCMQLSQIQGLIGSV-EEQLAQFLCEMEQQ--NKEYKIL
LDMKMWLELEIT----TYHRLLEGEDRGSPG----PYF--------------------KA
P-----ASPAAVTTCQVPTI----VE------------EVQDG--KVISSREQVH--Q--
-----------------------------------TTR----------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
---------------------------MSCRLQSS-------------------------
--------------------------------------STSYGG-GFGGGSCQLGGGRS-
-----------------------------VSTCST-------------------------
------------------------RFASG---GSACGYGG---GASF---GFGSGAGSGF
GGGFG------------G-----GFGG----------------------GFGGGFG--DF
GGADGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQSPSS--
P--E-RDYSPYYKTIEELREKILAATIDNN------------RIILEIDNARL-AADDFR
L-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFNSK
----------------SAELN-KEVSSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSTK---AGLENTVAETECRYALQLQQIQGLISSI-ESQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDARMTGTASSSSS----------------S-SAS-
--------------RRISD--TPRPS----------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSAR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISTLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGI-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
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-----MTN-----------------GQRPSVCRLHL--------PACEFLRPRYPPTPPL
PAGRHKRRGAKARPLL-TRQLGACRYCPPFAMTS---FSYRTQ----------SFGGL--
-G-------------------------GGSLR-------LGT-G-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRFVSS-GAGG--------
------------------------------------------------------------
-----------LGGGFAV-----RMG----------------------------------
--GQDALLGGDEKITMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQRQGP-G--
---PARDYSHYYKTIEDLRSKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEK-NRKDAE---AWFISQ
----------------TEVLT-KEVATNKEM--VQTSKTEITELRRTVQ---SLEIELQS
QQSMK---AALEGTLADTEARYEVQLAQIQALISSL-EAQLSSLRADTERQ--NLEYQQL
MGVKSRLEQEIA----TYRSLLEGHDAH--------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRSGTRPST--GSLRLSST---A-GSFGAGNACGV-PGIGSGF-SCAFGGSSL-AGS
A------------------GGSSSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELEQKIKAWYEQYGP-GSCRGLDHD---YS-RYLPIIEDLKTQIIAATTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRALDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
LMLNNMRAEYEALAENNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAHIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVYLEKEIETYCLLIGGDEGACKTSSYKSKDYGSGSVGNQVK-DPTKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-TLGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYHRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
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-------------------------------------------------M-----SVRFS
SASRRLGSCGG--AGSVRLSSG---G-ASFGVGSTGSV-PGFGSGF-TCAFGGSSSAGSY
SGG----------LG----GGSASCTAFTGNEHGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFTVIDDLRNQIISATTSNANI
VLQNDNARLTA-DDFRLKFENEQALHQSVDADVSSLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCTKS----K--GYGGPGNQIKVDPSKATVV
KTIVEEIDPHGKVLSSRVHTVEEKSTKVNNMKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVCTSALSRRSSS---Q-N----GVAGR--
---------------PWGASAS--SV-AGG-----YGGT----ASGFGV---G-----C-
GGIFSA-A---SM--FGSG---SGFSGGSA------------------------------
-------------GCL---PGLGSAYGGPLRGGAGGM-----------------------
-------------------------------G--MGI---AGSSG----G--GSL--CIF
SGNDGGLFSGSEKETMQNLNDRLASYLGKVRSLEEANAELE---NKIREWYETRRT--GD
AGSQ-SDYSKYYPLIEDLKNKIISASVSNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRKVLDELTLTRADLEAHLENLTEELAYMKKNHEE----
-ELQSFQAGG-PGEVNVEMDAAPGVDLTKVLNEMRAQYEAMAEQ-NRKDAE---AWFLEK
----------------SGELR-KEISSNTEQ--LQSSKSEVTDLKRMVQ---NLEIELQA
QLAMK---SSLEGSLAETEGGYCCQLSQVQQLIGSL-EEQLQQVRADAERQ--NADHQRL
LGVKARLEMEIE----TYRRLLEGDGQGGGFDENS---TLSVSKP---------------
---------------------------------------QTPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVQELEEEM----------------------
------------------------------------------------------------
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-----------------------------MSVRYSSSSKQFSS---TRS----GGGGG--
-------------------GGGGSSVRVSSTKGS-------------LGGGYS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG--------------------FG---
-----------------------------G-GSFGGGYG-------------GGSFGGGC
GGGSFGGGSFGGGGSFGG----GSFGGGSFGG--GSY--------------GGGFGGGGF
GGDGGSLLSGNEKVTMQNLNDRLASYMDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYKTIEDLKGQILTLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLSKSDLEMQIESLTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEK-NRKDAE---DWFNQK
----------------SKELT-TEIDSNIEQ--MSSHKNEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLEGEGSG--GGGGRGGGSHG-------------------
--------------GSYGG-------------------GSSGGG-SYGGS----------
----SG---------GGGGSYGGGSSGGGSHGGSSGGGYGGGSSSGGG------------
---GGHGGSSGGGYGG-GSSS----------------------GGQSGSGGFKSSGS-G-
GGD---QSSKGPRY----------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSKRSYARPSTGS--L----R---G-ASFGAANACGV-AGIGSGF-SCAFGSSS-TGGN
T------------------GVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYTSGNAGNQSK-DSPKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLG--------SVRLSSA---G-AALGAGNACGV-PGIGSGF-SCAFGGSSLAGGL
G------------------MGGASCGAFTANEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRSQIISATAHNANI
ILQNDNARLTA-DDFRMKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLSEE
LAYLKK--NHEE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCRLIDGDEGSCVKS----K--GQGGPRNQTK-DLSKTAIV
KTVVEELDPRGKVLSSRVHTLEEKSTKVNNKN----EQRIPS--------

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-------------------------------------------------M-----SLRLS
SGSRRSYARPSTGS--L----R---G-ASFGAGNACGV-AGIGSGF-SCAFGGSS-TGGN
T------------------GVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYGSGNAGTQIK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MFCSAQKGSCS-------SRVSS---S-------SSGA-V
---------------GSRGCTGGSSF-GSGSSCGLGGGS----AWGFQGSS-S-----S-
----------------------WGLSGGSKGS-----------------------VGGGF
GSCSVR--GGFGAASS-----------------YGGGS----------------GFGGGS
G--------FGGGSGFGG---GSGFGGGSSGG----FSNYGG--S-----VGGGLG-G-I
SGYDGGLLSGSEKQTMQDLNDRLANYLDKVRALEEANTDLE---TKIKDWYGKHGSV--K
DGCG-RDYSQYYSVIEDLKNQIISATCENA------------RMTLQIDNARL-AADDFR
M-KY-EHELCLRECLEADINGLRKVLDEMTMTRCDLEMQIEGLTEELVFLRKNHEE----
-EMKCMQGSS-GGDVTVEMNAAPGVDLTKLLNDMRAQYEAMAEQ-NRQEAE---KQFNER
----------------SASLQ-AQISTDAGA--ANCARSEVMELKRTVQ---TLEIELQS
QLALK---CSLEGTLADTEAGYVAQLSGIQAQISSL-EEQLSQIRGETQCQ--SAEYECL
LNIKTRLEQEIE----TYRRLLNGDGGGC-------DYRNLVSRN---------------
-----------------------------------------------------------V
V-----------------------------------------------------------
---------------------------------------------------LSD--S-GS
C----AGQGKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGRVVSSQVSNI----SEVKIK----------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
----------------------MSL-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSVGGYG------
------------GG------I-SCGFGGGAGSAFGGGCG---------------------
-----GGLGGGFGGGFAG-----GFG--------------------------------DF
CAGDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANTDLE---VKIRDWHLKQSPSS--
---PERDYSAYYKTIEELREKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELSLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHTK
----------------SAELT-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENSVAETECRYALQLQQIQGLIGSI-EAQLSQLRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSAGNVSPRSTSVTTTA----------
-------S------AS-----V----------------TT-------T-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MTTTFLQ-SS-S---S----------TFGGG--
SH------------------------RGGSLW-------AGG-G-GFGGGNLYG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------M-SCGFGGGAGSGFGG-------------G-F--------
----GGGVGGGFGGSFGG-----G-----------------------------------F
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPTS--
---PERDYSHYFKTMEELRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARTDLEMQIESLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRALAEMREQYEAMAEK-NRREAE---AWFFSK
----------------TEELN-KEVASSTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLETSLAETECRYATQLQQIQGLIGGI-EAQLSELRCEMEAQ--NQEYKVL
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGVGISAAAL---GSGGS------------
-----------SSSGNLHIKIE----------------ETVDG--KK----------FS-
------S--HQEI-----------------------------------------------
------------------------------------------------------------
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--------------------MSFQLSSGSKQMC--SGA----------------------
---G-----------SVRL------SG----KGTGYGARNVCG-----------------
-------------------------TLGA--GSRFSCTLGGV-SSG--------------
----------GGFYKGSGGLGSRFCMGFLGNENGLLSGN-EKATMQNLNDRLASYLDHVC
AL---EEANADLEQKIKGWYEKYRPGSCPGLDHDYSNYFSIAEDLKKQIFSITTCNANVV
LQNDNARLTADDFKLKYEHELALHKNIEGNINSLRRVLDELVFCTNDLEIQCEMLTEELT
YLKKNHEEEMKVLQGAVGGDVNVEMNAAPGMDLTVLLNNMRTEYEDLAEQNRKDAQACFK
EK---------------------------------SALLQQQVSDDAGAATAARNELTEM
KRNLQTLEIELQSFTAVKHSHECSLAETEGNYCLQLQQIQDQIGVVEGQLQQIRTETEGQ
ARDYEKLLDIKLFLEKEIETYRNLIEEE ERGSKSTCYKSKGN-GPVNSGN-----QVKVD
TGDPAPVP-PQDRSGSL--V-G---G-P--ALGLEMLA-AGIGNGF-SCAFSGTS-SGGN
A------------------VGSNSCAGFTVNEGGLLSG NEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDRD---YS-KYFPIIDDLKIQIVASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
ITYLKK--NHKE----------------------EMQVLQCAAGGNVNVEVNAAPGVDLT
VLLNNMRAEYEDLAEQNRRNVEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCEQLTQIQAQIGALEEQLHQVRTDTEGQK
LEYEQLLDIKVHLEKEIKTYCLLIGGDVGACKSEGYKSKDYGSGNVGNQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSPSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTLLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLR-------VGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------SG------M-SCGFGGGAGSGFGG-------------G-FG-------
-GGFGGGFGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANTDLE---VKIRDWYQKQSPAS--
---PERDYSHYFKTIEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRKVLDELTLARTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLSEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITELRRTMQ---GLEIELQS
QLSMK---AGLENSLAEIECRYATQLQQIQGLISGL-EAQLSELRCEMEAQ--SQEYNML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGIREASL---GGGG-------------
-------------SSSFHIKVE----------------ESVDG--KV----------VS-
------S--RKRE---------------V-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MATCSRQFTST-SMK----------------GS-
CGIGG-----------------GSS-RVSSIL---------------A------P-----
---------------STYG---------------GLSV-SSSRFSSGGA-CGLV------
--------GGYAGSF----SSGS---------SFGG--------------GYGGALGVNF
GG----GFGGG-------------------------------------------------
---DGGLLAGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRREAE---DWFFSK
----------------TEELN-REVATNTEA--LQSGRTEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQDMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------AQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------SHEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-------------------------------------------------MS---------
-----------------------------LSVCTSGLSRRSSS---Q-N----GTAAR--
---------------PWGASAS--SV-AGG-----YGGM----ASGFGV---G-----C-
RGLISA-A---SM--FGCG---SGFSGGST------------------------------
-------------CSL---PGLGTAYGGPLGGSLGGL-----------------------
-------------------------------G----I---GGSSG----G--GSL--CVL
SNNDGGLLSGSEKETMQNLNDRLASYLGKVHALEEANAELE---NKIREWYETRRT--GD
SGPQ-SDYSKYYPLIEDLKNKIISASVGNA------------QVILQIDNARL-AAEDFR
V-KY-ENELALRQTVEADINGLRRVLDELTLARADLEAQAENLTEELAHMKKNHEE----
-ELQSFQAGG-PGDVNVEMDAAPGVDLTKVLNEMRAQYEAMADQ-NRKDAE---AWFLEK
----------------SGELR-KEISSNTEQ--LQSSKSEITDLRRMVQ---NLEIELQS
QLAMK---KSLENSLAETEGGYCCQLSQVQQLIGSL-EEQLQQLRADAERQ--NADHQRL
LGVKARLEMEIE----TYRRLLDGEAQGDGFDESV---SLT--VSK--------P-----
---------------------------------------QTPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVQELEEAI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------V----------------------ALSSTMS---------
-----------------------------LLVQYSELRRQLSS---Q-S----GTLGR--
---------------ARGMSAS--SV-GSG-----YGGS----GLGFGG---G-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSCA---GVLGTAYGG--------------------------------
-------------------------------GLGIGF---GGSPG----G--GSL--CIL
SGNDGGLLSGSEKETMQNLNDRLASYLHKVRALEEANTELE---NKIHVWYETRGSGTED
PGSQ-NDYSKYYPLIEDLRNKIISASTGNA------------QLILQTDNARL-AADDFR
M-KY-ENERALRQSVEADTNGLRQVLDKLTLARADLEMQIESLVEELAYLRKNHEE----
-ELQSFQSDG-PAQVSVEMNAAPGVDLTRLLNNMRAQYEAIAEQ-HRKDAE---AWFIEK
----------------SRELE-KEISTNTEQ--LQSSKSEITDLRRAFQ---NLEMELQS
HLAMK---TSLEDSLARTEGDYCGQLSQVQQLIRSL-EEQLLQVRRDTECQ--NANHQRL
LNVKASLELEIE----TYRDLLDGEAQGDGVDETS---PVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SAKDPPK-------P-----------------RKIK-----------------
---------------TVIQTVVNEEMVSSQVQEFEALI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------M-AP-----PANLSLWHQGR-------------------------
--------------------------SVRAPSRHDFLQ----------------------
------------------------------------LQPVVRQVV-LRGLGGGSVSLG--
---------------------------------PGVAFCA---PSM--HW----GR----
----QPRR------------------VLCLSS-----------------SSLGGYS--GV
LAASDGLLAGNEKLTMQNLNDGLASYLDKVRALEAAICELE---VKIRDWYQKQGPGP--
---S-RDYSHYYKTIQDLRDKLLGATIENS------------RIVLEIDNARL-AADNFR
T-KT-ETEQALRMTVEADINGLRGVLDELTLASTDLEMHIKGLKEELAYLKKNHEE----
-ETSGLRGQV-GGQVSVEVDSAQGTDLARILSDMRSQYKVMAEQ-NWKDAE---AWFTSR
----------------TEELK-REVAGHTDQ--LQMSLSKVTDLRHTLQ-----GLELQS
QLSMK---ATLEGTLAETEARVGAQLLG--------------DVGADSKRQ--NQEYQQF
TDIKSRLQREIA----TYRSLLEGQEDHCNNLSASKVL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SVRFS
SASRRLG--------SVRLSSA---G-AALGAGNACGV-PGIGSGF-SCAFGGSSLAGGL
G------------------MGGASCGAFTANEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRTQIISATAHNANI
ILQNDNARLTA-DDFRMKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLSEE
LAYLKK--NHEE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCRLIDGDEGSCVKA----K--GQGRPGNQTK-DSPKTAIV
KTVVEELDPRGKVLSSRVHTLEEKSTKVNK-T----EQRIPS--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTTFLQ-TS-P---S----------SFGGG--
SA------------------------RGLSLR-------AGG-G-CLGGGSLYG------
---------------G-GG--------------GRSISASSPRFVSSGFGGSYG------
------------GA-------------------ASG-------------G-FG-------
-GGFGGGLGGSFGGGFSG-----SFG--------------------------------DF
VGGDGGLLSGNGKVTMQNLNDRLASYLDKVRALEEANAELE---GKIRDWYQKQSPAS--
---PERDYSHYFQTMEDLRDKILAATIENS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EMKEYGSQL-AGQVNVEMDAAPGADLTRALKEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLISSI-EQQLSELRSEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGIGTRDASL---GGGGGG-----------
--------------GKVRVHVE----------------ESVDG--KV----------VS-
------S--HKRE---------------V-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFASS-SSMK---------------GS-
CGLGG-----------------GSS-SLSTVL---------------A------P-----
---------------STYG---------------RLSL-SSSRFSSGGACG---------
-------------GF----SS---------SSGFGG--------------GYGGGLGGGF
RN----VLGGIYGSGF-T-----GFDSG------------------------------L-
GG-GDALLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLKSKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRREAE---EWFFSK
----------------TEELN-REVATNTEA--LQSGKSEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQEMIGSV-EAQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------AQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VV------------DVHDG--KVV------S-----
---------SHEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
---------GDEKVTMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQKQGP-G--
---PARDYSHYFKTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETELNLHMSVEADINGLRRVLDDLTMTRSDLEMQIEGLKEELAYLKRNHEE----
-EISALRSQV-VGQVSVEVDSAPGTDLTKILSEMRSQYEVMAEK-NRKDAE---AWFISQ
----------------TEVLN-KEVATNTEM--IQSSKTEITELRRTMQ---GLEIELQT
HLSMK---ATLEGTLAETEERYRVQLAQIQALIGSL-EAQLSNLRADTERQ--NLEYQQL
MGLKSRLEQEIA----TYRSLLEGQDAHY-NSLPGPKG---L------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YSGVYGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSCSRQFTSS-SSHEG-------APCGIGGG--
------------------------S-SCSSVL---------------AGGSCRAP-----
---------------SA-GG--------------GMSV-SSSRYSF-GA-CGLG------
--------GGYGGGF----SS--SSFGGALGGGFGG--------------GYGGGLG---
-------------AGFGA-----GFGAG------------------------------F-
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---A-KDYSPYFRTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELTLRQSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYMRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDVE---AWFLSK
----------------TEELN-KEVASNSEL--VQTSRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQGLISSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSS-QH-MSSQSYS--SRDV--ISS---SS--
----------SSSGRQTRSIL---KE---------------------MDSSSFSQGQ---
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRSGPRPSA--GSLRLSSG---A-ASYGASNTCGV-SGIGSGF-SCAFGSSSL-GGN
A------------------GAGSSCASFA-NEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELEVKIKSWYEKYGP-GSCRGLDHD---YS-RYLPIIDDLKAQIIAATTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
LLLNNMRSEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIDTYCLLIGGDEGACKSGSYKSKDYGSGNVVNQIK-DSTKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSPSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----GGL
GA----GL--------GA-----GFGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVGANINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYGG---------------LSV-SSSRFSSGGA-CGMG------
--------SSYGGGF----SS--SSFG-GYGGGIGC--------------GIGGGFGGGF
GGGFG------------G-----GLGG---------------------------------
---GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---I-KDYSSYFRTIEDLKSKIIAATLENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLESSLEETKGRYCMQLAQIQGLISGV-EEQLAQLRCEMEQQ--SQEYNIL
LDVKTRLEQEIA----TYRRLLDGEDAHLLSSQS-PP---IFSPFFAV--FS--------
-----------SSSRQPRSIL---KE------------QGS---------SSFSQSQSQ-
------SSRN--------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------S---S-------RAGGSS
---------------SIRASTGGSSF-NGSSKCSLGGGS----TRGFRGGT-S-----C-
----------------------CGLSGGSSGGFGGS-------------------FGGGF
GSCSVG--AGFGGNSG-----YGASSAFGSG--FGGSS----------------G-----
---------FGRGSG---------FASGAGGG----FSSYGAG-------V----G-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANADLE---NKIKEWYDKLGPGSRD
GVPG-KDYSKYYAVIEDLRNQIITATTENA------------GIILQIDNARL-AADDFR
L-KY-ENELHLRQSVEADINGLRKVLDDLTMTRSDLEMQVESLTEELAFLKKNHEE----
-EMRSMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ATSARNEITELKRTLQ---ALEIELQS
QLAMK---CSLEGTLADTEAGYVAQLSEIQAKISSL-EEQICQVRGETECQ--NSEYQQL
LDIKTRLEKEIE----TYRCLLDGEGHGS-------CFGGFDYRKS--------G-----
------------S-RNM----E--------------------SR-D-------------V
G-----------------------------------------------------------
---------------------------------------------------AGDSRS-GS
C----SGQGRDP---SK----T-----------------RVTK-----------------
---------------TIVEEVVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MP-----
---------------PALRG--------------GLSV-SSSCLSSGGA-CGLG------
--------GGYGGGF----GSS-SSFGS----GFGG--------------GYGGGLGAGF
G-------------------------GG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDCLASYLDEVRALEEANADLE---VKIRDWYQRQQPSE--
---I-KDYSPYFKTIEDLRNTIIAATIENV------------QPILQIDNVRL-AAGDFR
T-KY-EHELALRQTVEADVNGLCRVLDELTLARTDMEMQIEALKEELAYLRKNHEE----
-EMLVLRGQT-GGEVNVEMDAAPGVDLSCILNEMHYQYQQMAKK-NRRDAE---AWFLSR
----------------TEELN-KEVASNSKL--VQSSCSEVTELQRVFQ---GLEIELQS
QLSIK---ASLENSLEETKGHYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDMKTQLEQKID----TYRRLLGCEDTQ--------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MSTSFRQYTSS-SSVKG---------GSFG----
----G-----------------GSS-RLSHL-----------------GRGYVAP-----
---------------GIH------------SGLGGISV-SSSRYV-----SGVG------
--------SALG-------GGYGGS-------------------------SYCSSYGGGF
GG------------GFGG-----GFGGG---------------------------S--FV
AGGGDVLLAGGEKETMQNLNDRLASYLDKVRALEEANTDLE---VKIKEWYKKQGPSP--
---E-RDYSPYFRTIEELRSKILAATVDNA------------SIVLQIDNARL-AADDFR
N-KF-ETEHALRVNVEADINGLRRVLDELTLARADLEMQIENFKEELVYLRKNHEE----
-EMSIFRSQS-GGEISVEMDAAPGVDLTKILSEMREQYESLAEK-NRKDAE---QWFFSK
----------------TEELT-REVAINTEQ--LQSGKTEITELRRTYQ---NLEIELNA
QLSMK---AALESSLADTEARYGAQLSQIQVLITNV-EEQLADLRCEMERQ--NHEYKML
LDVKTRLEQEIA----TYRRLLEGEEAHISSQYNAAI-----------------------
S-----GREVSKTSRQVRMI----VE------------EVENG--KVVSSREQLQ--QS-
--------------------------------AY--------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SGSRRSYARPSTGS--L----R---G-TSFGAGNACGI-AGIGSGF-SCAFGGSS-TGGN
T------------------GVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLENVQA
LQEANADLEQKIKSWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCSQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSASYKSKDYGSGNAGNQIK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LPSNSIS---------
-----------------------------LSVRNSGLSRRLSS---Q-S----GIAGR--
---------------PRVMSAS--SA-GSG-----YGGS----AFGFGA---S-----H-
GGGFSA-A---SM--FGSS---AGFGGGSG------------------------------
------------SSL-----------AGGLGTGYGRA-----------------------
------------------------MGGGGFGGLGIGF---GGSSG----N--ASL--AII
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
PASQ-SDYSKYYPLIEDLRNKIISANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRRVLDELALSKTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCGQLSQVQQLIGSL-EAQLLQVRADAERQ--NADHQRL
LDVKARLELEIE----TYRRLLDGEAQGDGLDESL--LFVTDSKSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------K-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSG-RISSVL---------------TGGSYRAP-----
---------------SAYG---------------GLSV-SSSRFSSGGA-CGIG------
--------GGYGAGF----SSSSSSSGGGFGGGY--------------------------
----GGGLGGGLGGGFGG-----GLGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIXXXXXXXXXXX--
---X-XXXXXXXXXXXXXXXXILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMISGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAXXXXXXXXXXXXX--------------------
------XXXGSSTNRQIRT-K---VL------------DVHDG--KVVSS--HEQ-----
---------VIRSKN---------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MATTFLQ-T--S---S----------TFGGG--
ST------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGYG------
------------GG------M-SCGFGGG----------------------AG-------
-SGFGGA----FGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PERDYSHYFKTMEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARTDLEMQIEHLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQSSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGLISSL-ESQLSELRCEMEAQ--NQEYNML
LDIKTRLEQEIA----TYRNLLEGQDAKM-AGIGVREASL---GGGSGGG----------
-----------SSSSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSVRYSS-RKQYSS---SRS----GGG----
-------------------GGGGSSLRISSSRGS-------------FGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG---------------------G---
----SG--GGFGGGSF---GG---GYGSS---SLGGGFG-------------GGSFG---
-GGSF-----GGG-SFGG----GSFVG-------GSF--------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNA--G
QREP-RDYSKYYQIIEDLKNQIINLTNDNA------------NVVLQIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRNQYEQLAEQ-NRKDAE---AWFNEK
----------------SQELT-TEINSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISSL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGS------------------------SRGG-----
---------------GR-----------------AYGGSSGG-G--Y-------GGS--S
GGG---------------------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLGSGGP-AAGSVRLSSG---G-SGFGAGNTCGV-PGIGSGF-SCAFGGSASAGSY
GGG----------LA----GASASCTAFLGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLRNPIISASTSNANV
VLQNDNSRLTA-DDFRLKYENELALHQSVEADMNGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAET--WFNEKSATLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLTQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDLKVHLEKEIETYCRLIDGEDGSCVNL----K--GYRGPGNQIK-ESAKTTLV
KTVV-EIDPRGKVISPRIHTIGEKSTKVNTQTG--TRVA-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MSTCSHQFTSS-RSMKG--------SCSIGGSI-
---GG-----------------GSS-RISSV-----------------------------
---------------------------------------LAGGSCHAPT-CGLG------
--------GGYGGGF------GSSS-------------------------SFASGFGGGY
GGGLGA--------------------SV---------------------------V--AW
------VVALLVKVTMQHLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQWPSE--
---I-KDYSPYFKTIEDLRHKIIAATIENA------------QPILQIDNARL-AADDFR
T-NY-EHELALRQTVEAGVNGLCRVLDELTLARTDLEMQMEGLKEELACLRKNHEEMRLL
LEMLALRGQT-GGKVNVETDAAPGVDLSCILNEMCNQYEQMANL-TF---H---SAFLPQ
----------------TKELN-KKVASSSEL--VQSSRSEVTELQRVFQ---GLEMELQF
QLSVK---ASLENSLEETKGCYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDMKTRLEQEIA----TYRRLLEGEDLSDSF----SPP--LLSP--TV--F---------
------TSSSSSSSCQTWPI----LK------------E--QG--SSSFSQGQCS-----
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------KQSTWSTMALSVRTSGGSRQFSS---R-S----GLGGG--
---------------TLRMSNA-------SAAGGGFGGS----GFGFGG---G-----A-
GGGFGT-T---SL--LGSG--------------------------------------SSF
-----S--GGFGS-----------------------------------------------
------------------------------SCSGAG--------------FGGGF--GTG
GGGDGGLLSGSKKETMQNLNDRLAAYLDKVRSLEDANTELE---RKIREWYEKNGPGTGV
PGSG-NDYSKYYPIIEDLRNKIINATIDNA------------RIILQVDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTRADLEMQIESLNEELAYLKKNHEE----
-ELQGFQSNA-VGQVSVEMDAAPGIDLTKLLNDMRGQYEVIAEQ-NRKEAE---AWFNEK
----------------SGELK-REISTNTEQ--LQSGKSEITDLKRTLQ---SLEIELQS
QLAMK---KSLEDTLAETEGGYCAQLSQMQLQIGNL-ESQLFQVRADMERQ--NAEYQQL
LDIKSRLEMEIE----TYRRLMDGEFVSGGQGLSFESSSLTGSKSQ--------------
----------------------------------------TQSL-DS------------S
Q-----------------------------------------------------------
------------------------------------------------------------
----------DPTK-------T-----------------RKIK-----------------
---------------TIVEEVVDGKVVASHVKEVEEKI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------TRVSS---S-------RAGGSS
---------------SIKVSGGGSSF-SSRSRCGLGGGS----AQGFRGGA-S-----S-
----------------------CGLSGGSSGGFGGS-------------------FGGGM
SSCSVG--GGFGGISG-----SGAGFVGGSG--FGG------------------------
------------GSGFGG---GSGFGGGASGG----FYSYGGG-------MGGGAG-G--
GIGDGGLFSGGEKQTMQNLNDRLASYLDKVRALEEANTDLE---NKIKEWYERFGPGSGD
GGSG-RDYSKYFAVIEDLKNQITSATIENA------------GIILQVDNARL-AADDFR
M-KY-ENELRLRQSVEADINGLRRVLDEMTMTRSDLEMQIESLNEELAYMKKNHEE----
-EMKSLQASS-GGGVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ANSAKTEVTELRRTLQ---ALEIELQS
QLAMK---NSLEGTLADTEAGYMSQLSEIQMQISSL-EEQICQIRGETECQ--NAEYEQL
LDIKMRLEKEIE----TYRHLLDGEGGG---FGGS-DYRNSGSQNT--------S-----
------------S-RNR----G--------------------SR-DL-------------
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
F----AGQGRDS---NK----T-----------------RVTK-----------------
---------------TIIEDVVDGRVVSSQVSNV----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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----------------------------------------------RTTM-----SLRFS
AGSRRGCSRPG--AGCG-------------------------NSNF-SCSLGGGPAGGSF
GSSLNGPGGNHIGGS----LGNASCSAFVGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKYGP-GSCRGLDHD---YS-RYFPVIEDLRNQIVSSTTCNANV
VLQIDNARLAA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQYETLSEE
LTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSATLQQQISDDAGAATSARNELTEMRRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCVQLSQIQAQIGTLEDQLQQIRTETEGQK
LEYEQLLDIKIHLEKEIETYCRLIDGDGESCF----QSKSYVPGGLGSPSK-DLSKTTLV
KTVVEEIDQRGKVLSSRVHSIEEKSSKLSAIKT--EQRTPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSSTS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-ASRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------RG----------------------------------------------
-----------YGGGYGG-----I------------------------------------
LAASDGLLAGNEKLTMQNLSDRPASYLDKVRALEAAKGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLRDKILGATIENS------------RIVLQISNARL-AADDFR
T-EF-ETEQALRMSVEADINGLRRELDELTLARTDLEMQIEGPKEELAYLKKNHEG----
-ELSVLRGQV-GGQVSVEVDSAPGTDLAKILSDVRSQYEVIAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHREQ--LQMSNTEVSDLRRTLQ---GLEIELQS
QLSMK---AGLEGTLAETEARFGAELADIQARISGI-EAQLGDVRADSERQ--NQEYQRL
LDVKSRLEXXXX----IETILAMVKPHLY-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATTFLQTS---S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRTISASSARFVSSGSAGGYG------
-------------------------------GGFGG-------------G-AG-------
-SGYGGGFGGGFGGGFGS-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWYQRQSPTS--
---PERDYSPYFKTIDELRDKILAAAIKNS------------QVILEIDNARL-AADDFR
L-KH-ENEMALRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQL-AGQVNVEMDAAPAVDLTRVLSEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTIQ---GLEIELQS
QLSMK---AGLESTLAETECRYAAQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSRM-AGIGTREASL---GGGGG------------
--------------GKVRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

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MS--------------------QYS-FKQSTKSVQYSSGSNAGG-GYQCGV---------
--------------GGGFGGD-GGF-----------------------------------
----------------GGGAGYGAGFGAGGYEGGAGGFGG---GGYGGGAGFGGGAGFGG
GAGFGGGAGFGGGA---------GFG--GGAG------------------FGGGAG--FG
GGPSGGLHMVSEKETMQNLNDRLASYLDKVNALEAANAELE---RKIKEWYDKQKPSTTT
GEGA-KDYSKYYKDIEDLKAKIIAASKENA------------ALLLQCDNARL-AADDFK
Q-KY-ESELHLRQTVEADINGLRRVMDELNLAKTDLDSQFQGLTEELASLKKNHED----
-EVKGVQVTE-AGKVKVEMNAAPSNDLTKRLNDMRAQYEDLAKK-NRQELE---NKFNAA
----------------TGPVK-EKIKEDVKE--DTTVKTQISDLKRSLQ---ALEIELQS
LLAMK---KSLELQLAETEGRFCMKLSVLQENIASI-EQHLEQLRAESECQ--KDEYDQL
LEMKTKLENEIK----TYQSLLDKLGAIQVTQGQGQ-----------------GQ-GQ--
-GQG--QAQDQSRGQAPQKH----------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MATTFLQ-TS-S---C----------TFGGG--
SA------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFMS-GSGEGYR------
------------GS------M-SCGFGGGAGGGFSG-------------G-LG-------
-GGFGGGLGGV----F-------------------------------------------F
GGGDGGLLSGNEKVTMQNLNNRLASYLDKVHALEEANADLE---VKIRDWYQRQSPAS--
---PERDYSRYFKEIEGLRDQILAGDMDNS------------QVILEIDNARL-AADDFR
L-KY-ENELSLRQTVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKRNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQSSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGLIGGL-EEQLAQLRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRRLLEGQDAKM-AGIGTRE-------AALGG-----------
-----------GGSSNFRIKVE----------------ESVDG--KV----------VS-
------S--HKRD---------------V-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSTRFVSGGSAGGYG------
------------GG------V-SCGFGGGAGSGFGGGYGG--------------------
------GLGGGFGGGFAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYHKTIDELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGVPSSAGSVSPRSTSVTTT----------
-------S------SVS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRL-------AGSVRLSSG---G-AGFGAGNTGHL-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSTSCAAFTGSEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIISATTSNANV
ILQNDNARLTA-DDFRLKFENEQALHQSVDADVSSLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
LLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATSSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCVKS----K--GYGGPGNQIK-DSSKTTVV
KTIVEEIDPRGKVLSSRVHTMEEKSTKVNNMKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------YNFRQSQSSSG-GGSGCSCV-GGGSSG
GGGSSGSGHSGSGSGGGGFSSGSSIRHTSTGRNSQGFS---GVGR-GSGYGGGSMRRGSF
S------------GGFGSSSGFGGGYGGGS---FGG------------------------
------------GFGPAG-----GFGGGSLGG-----------------GF--GGA--GF
GGDDTGFLSNNEKSTMQNLNDRFASYLNKVKSLEAENNQLE---TLIREWYQKHGQTS--
E--P-KDYSSYYTEIDQLVNELISASLESN------------KILLDVDNARM-AAEDFK
L-KY-ETEYGLRQNVDADLQGLRPLLDKLTMDKSDLEMQYESLHEELVHLKKNHDE----
-VMKSQHHQS-GGDVNVEVNSSPGQDLTKTLNDLRQEYEEIIMK-NRKEVQ---QWFEAK
----------------MEEAR-QQQSPESQE--GGSGRHQITELTREYQ---TLEIELQT
QLSTV--CDALQNNLNNTEGGYNMQLQQLASQIEPV-EAELAGIKGEIQNQ--TQEYQTL
LGIKTYLEQEIN----QYRQLLEEGKQLAIYSKLFTHH----------------S-IYS-
--I--------SFGVGFGL--WANVQGGGSGGTGSYGGSSGGG--R--------------
---------------HSVGG--------ISGGSSGGGGSGGGHSYGGI---S--------
-RGGS---SGGGGESG-SGHSYG----------GISEGGSS-GGGRSTSGG-RHSTSGIS
HGG---S-SIG------------I------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------SQ-
--G-G-----------------------SSRGRE----SGGVGG----------------
-----------------HS-SGRISPGGS---------SGGGGSGGRGGQSHS--G-ISH
GGSSGGGGSGGRGGQSHSGISH---G-GSAGGGSA----GRPSSGGVSQGGSSGRRGSES
-GR-QSPSGGHSGGGRGSVGGGGHSSGGISHGRGSGGGSHHLSSSS--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-------------TIEELQNQIISATVDNN------------RMLLDIDNSKM-TADDFR
M-KY-ENELVIRQTVEADINGLRNLMDDLTLVRSSLESELESLKDELIALKRNHEE----
-EMRQLQSQT-GGDVSVEVNAAPGEDLTKILNDLRDEYEQIIEK-NRREVE---QWYEVK
----------------IQEVN-QQVTSSSQD--IQTSSHQLSELRREMQ---NLEIELQA
QLSTK---SSLENSLAETESRYGRMLQQIQAQVNSV-EEELGSIRCEMEGQ--SQEYKML
LGIKTRLEQEIQ----QYRALLQEGQQDLVASQG--------------------------
----------------------------AF-Q---------G--------------GG--
--------------------K-SSQ-------S---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------Y----------------------------SA---S-YSH
SQCG-D------------------------------------------------------
---------------------------I--------------------------------
------S--GQS--------------------RVC-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGLGG-----------------GSS-RV-SIL---------------GGGSGRAS-----
---------------SVYGG----------SGFGGMSV-TTSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GYGSG--AGF
GG----GLGGGFGGGFGG-----G-GGG------------------------------Y-
GG-MDGLLAGGEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---A-KDYTPYFNTIEDLKNKILEARVENA------------RILLQVDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRSQV-GGDVNVEMDAAPGVDLSRTLAEMREQYERMAEK-NRKDAE---EWFFSK
----------------TEELN-REVASNSEM--VQSGKSEISELRRSLQ---SLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQGLITNV-EEQLAQLRCEMEQQ--NQEYKVL
LDVKTRLEQEIA----TYRRLLEGEDAHLAS----------------Q--FSSGSQSSR-
--------DVSSTSRQVY-SK---VL------------DVHDG--KVVSS--HEQ-----
---------VIRTKN---------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVSFS
SASKQLGS-------PGRLSEG---R-PSFPAGNPCGV-PGIRSGF-SCAFGGSWSAGGL
--G----------------TGSASCAGFAVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLQNQIISATTSNAGV
VLQNDNARLAA-DDFRLKYENELALHQSVDADINGLRRVLDELTLCRADLEIQLETLTEE
LAHLKR--NHEE----------------------EMKALQCAAGGNVNVEVNAAPGVDLT
VLLSNMRAEYEALADQNRRNAEA--WFSEKSASLQQQISEDIGSATSAKNELLEMKRMAQ
GLEIELQSSVAL----KHSLECSLSETKGNYCSQLAQIQARIAALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDKESCFKS----K--GQGGPGSQIK-DASKPAVV
KTVVEEIDPRGNVFRSRIHTIEEKPTKVNT--S--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------AGGSCHAP-----
---------------STYG---------------GLSV-STSRFSSGGA-CGLG------
--------GGYGGGF----SSSSS-----YGGGFGG--------------GYGGGLGAGF
GG----GLGGGFG----G-----GLGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------------ILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVDADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEK-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLESSLAETEGRYCVQLSQIQSQITSL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLDGEGGSGGGSYGGGRGGG--------------------
----------------YGG----------SSSGGGYGGGSSG-G-GHGSS----------
SGGGHGG--------------SSGGGGYGGGSSGSGGGYGGGSSGGGGGYGGGSSSSGGG
YGGGS--SSSGGGYGG-GSSGGG----------GG---SGGGYGGGSSSGGHKSSSS-GS
VGE---TSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVCTSALSRRSSS---Q-N----GAAGR--
---------------PWGASAS--SV-AGG-----YGGS----ASGFGV---G-----C-
GGLFSA-A---SM--LGSS---SGFSSGSA------------------------------
-------------GCL---PGLGSAYGGPLRGGAGGM-----------------------
-------------------------------GMGMGI---AGSSG----G--GSL--CIF
SGNDGGLLSGSEKETMQNLNGRLASYLGKVRALEEANAELE---NKIREWYETQRT--GN
AGSQ-SDYSKYYPLIEDLKNKIISASVSNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRRVLDELTLTRADLEAQLETLTEELAYMKKNHEE----
-ELQSFQAGG-PGEVNVEMDAAPGVDLTKVLNEMRAQYEAMAEQ-NRKDAE---AWFLEK
----------------SGELR-KEISSNTEQ--LQSSKSEVTDLKRMVQ---NLEIELQS
QLAMK---SSLEGSLAETEGGYCCQLSQVQQLISSL-EEQLQQVRADSERQ--NADHQRL
LGVKARLEMEIE----TYRRLLEGDSQGDGFDESS---SLSVSKP---------------
---------------------------------------QTPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPSK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVHELEEEA----------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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--------------------------CITMSQRYGS-SRHYSS---SRS----GGGA---
--------------------GGGSSIRISSTRGSGYGA-------GSIGGGFS-----S-
AGGFGS-----------------------------R-------------------SVGGF
VGG-------FSSSSY---G----------GGSFGGSYGG----VS----CGGGSFG---
---------------------------------------------------------GLF
DGSDGGLLSGNEKVTMQNLNDRLASYLDKVKALEDSNSQLE---QKIKEWYEKYGNS--R
QREP-RDYSHYYDVIKDLKDQILTLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALHQSVEADINGLRRVLDDLTLAKTDLEVQLESLNEELAFLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTENLNLLRSQYEQLAEQ-NRKEAE---AWFNEK
----------------SKELT-TEINSNVEQ--VSSQKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCSQLSEIQAQITAL-EEQLQQVRAETEYQ--NSEYQLL
LDIKIRLENEIQ----TYRSLLEEGG----------------------------------
------------------GISGGVQ--GASSSSGAYGGSSAGSG-GVTSSG---------
------------------------------------------------------------
--------------------------------------------PRRGSSVVQGGSS-GS
GGESTSKSSSG-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTSYSYRH----SSATS----------SFGGL--
-G-------------------------GGSLR-------LGPGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SSGG--------
------------------------------------------------------------
-----------YGGGFTS-----GL-----------------------------------
-GRSDGLLAGNEKLTMQNLNDRLASYLDKVRALEEANGDLE---VKIRDWYQRQGP-G--
---PARDYSHYFKTIEDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLELQIEGLKEELAYLKKNHEE----
-EISALRGQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------TEELS-REVAGHTEQ--LQISKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISSM-EAQLSDVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRSLLEGQDAHY-NNLPTPKA---L------------------
------------------------------------------------------------
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------------------------------------------------------------
-----------------------MAATTTSIRQFSTS-GSVKG--------LCVPG----
----G-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGA----------GSCGNT----LSRFS-----AGFG------
--------GGYG-------G----GYTCSLGGGFGS------------------------
--------------SFGA-----GFGSS------------------------------LS
--SSDALLGGSEKETMQNLNDRLASYLDKVRALEEANADLE---VKIHDWYKKQGPGP--
---A-RDYSHFFKTIEELRNKILAATIDNA------------SLVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADTNGLRRVLDELTLARAGLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLEGSLAETEARYGAQLAQLQGLISSI-EQQLCELRCDMERQ--NQEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------ISQ
P-----TREATVTTRQVRTI----ME------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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------------------------------------------------IM-----SLRLS
SGSRRSYPRPS--TGSLRLSGG---A-GSFGAGNACGI-PGIGSSF-SCAFGGSS-SGAN
A------------------GTGNPCTGFTLNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTMQ
TLEIELQSLLAT----KQSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEHEQLLDIKVHLEKEIETYCLLIGGDEGACKSSGYKSKDYGVGNVGTQIK-DSAKPIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SASRKSCPRPTT--GSLRLSGG---G-TSFGTGNSCGI-SGIGSGF-SCAFGGS-SSGGN
T------------------AGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVESQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

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-------------------------------------------------M-----SLRCS
GESRHVGFQSP--AAAARPPSR---G-ASFGGSSTYGS-SVATSGF-SCGLGTGLG----
----SVAGGS---GT----LGNAACAGLAGSEGGLLSGNEKMTMQNLNNRLASYLDSVKA
LEEANADLEKKIKSWYEKYGP-GSCRGLDHD---YS-VYHLTIEDLKSKIIASTAANANV
ILQIDNARLAA-DDFRLKYENELSLHQNVEMDINGLRRVLDELTLCKTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRREAEA--WFQEKSASLQQQIFDDAGAASSARAQLTEMKRTMQ
TLEIELQSLLAT----GNLAPTQGNQGGGPF----FLKGAQIGALEEQLHQVRTETEGQK
LEHEQLLDIKAHLEKEIETYCRLIDGDGN----SCSKSKGFGSDSSGNPPK-DSPKTTLV
KTVVEEIDQRGKVLSSRIQSIEEKTSKMTNGKT--EKKTPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
C-------------------------RLQSSS-------TSYGG-GFGGGSCQL------
-----------------GG--------------GRNVSTCSTRFVSGGSAGSYG------
------------GG------M-SCGFGGGAGSGFGGG-----------------------
---YGSGFGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWYQKQSPAS--
---PERDYSHYYKTIEELREKVSP AQ---------------------------------G
K-GY -ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFQSK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLADTECRYALQLQQIQGLISSI-EAQLSDLRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSK--------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-----------------------------MSVRYTS-SKQFSS---SRS----GGGGGGG
-------------------GGGASSLRISSSKGS-------------HGGGFS-----S-
-GRFSS-G---SF--SRGSSGGGCFGSSSG-GYGG--------------------GFG--
-GGSFG--GGFGGGSF---GG---GFGGG---SYGGGFG-------------GGSFG---
-GGSYGGGGYGGG-GYGG------------------------------------------
-GGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---SKIKEWYEKHGNS--S
QREP-RDYSKYYQTIEDLKNQILSLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVDADINGLRRVLDELTLTKSDLEMQIESLSEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLESSLAETEGRYCMQLSQIQAQISSL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGSYGGGRG---------------------
---------------------------GGSSGGGSYGGSSGG------------GGHGGS
SGGGYGG--------GSSG-------GGGGHGGSSGGGYGGGSSSGGYGGGS----SGG-
-G-GGHGGSSGGGYGG-G-SS----------------------GGQSGSGGFKSSSS-GS
AGE---S-SKGPRSAENIWGNQ-----------------H--------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MLLSVPIPGLSRHLSA---Q-S----GVAGR--
---------------ATGLSASSPVR-G-------PGGG------AFGAGGFG-----C-
A-----------------------------------------------------------
-------------------GGLGTGQGGPLG-----------------------------
---------------------------GGCRGLGMAF---GGSPA----G--GST--GVL
CGLHGGLLPGSEKATMQNLNDRLASYLERVGALEEENATLG---QKIRDWYERCGA--ED
AGSQ-TDYSKYYLLIEDLRNKITSASTRNA------------QVTLQMDYARL-AAEDFQ
T-KY-ENELCLRQSVEADASGLRRVLDERTLARADLEVQIEGLAEELAYLRKTREE----
-ELRSFPADC-PREISVEIDAAPGVDLTRLLNDMRAQYEVLAEQ-NRKDAE---AWFMEK
----------------SGELR-KEISSNTQQ--LQSSRSEVTDVRRARQ---SLELELQS
QLALK---KSLEDSLAETEGGYCGQLSQVQRLVGSL-EAQLQQVLADAEGQ--GAEHRRL
LDAKAGLELEIE----TYRGLLDGEAAGDDLEESAS-E--TGSKPQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RTIK-----------------
---------------TIVQEVVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTICQFTSS-SSIKG--------SSGLG----
----D-----------------G-----SSR------------------TSCRLS-----
---------------GGVGA----------GSCRL-------GCA-----GGLG------
--------SALG------GSSYSSCYSFGSGGG---------------------------
---------------YDS-----SFG----------------------------------
--GVDGLLARGEKATMQNLNDRLASYLDKVCALEEANTELE---VKIRDWYQRQAPGP--
---Y--------RTIEELQNKV--GHLDNA------------NILLQIDNAHL-AAADFP
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMHIENLKEELAYLKKNHEE----
-EMNALGSQV-GGEINVEMDAAPGVDLSRILNEMRDQYEEMAEK-KLKDAE---DWFFSK
----------------TEELN-HEVATNSEL--VQSGKSEILELRCTMQ---ALEVELQS
QF------TSLEGNLAETENRYCMQLSQIQGLIGSM-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTSWSRRSPPTATCWRARIEG-------LLAPTHF--------------------KV
P-----ASPAAVTTRHVCSI----VE------------EVQDG--KVISSREQVH--QT-
--------------------------------TD--------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MASTTSIRQFSTS-SSMKG--------FCAPG----
--GSG-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGNMSV-TSSRFS-----AGLG------
--------SGYG-------G----GYSCSLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGNEKETMQNLNDRLATYLDRVHALEEANTDLE---VKIRDWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLSRADLEMQIESLKEELAYMKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------ASQ
P-----SREAMVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SGSRHICLWSG--TGSARPSSG---G-SGLGAGNACGV-PGIGSSF-SCAFGGSSSAGGY
--------------G----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIISATTSNANI
ILQNDNARLTA-DDFRLKFENEQALHQSVDADVSGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCVKS----K--GYGGPGNQIK-ESSKTTMV
KTIVEEIDPRGKVLSSRVHTVEEKSTKVNNVKS--EQRVPS---------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SFRLS
SGSRRICSR----PGSVRLSSC---G-GGFGAGNSCGGGSGVGSSF-SGTLGGASSGGSY
SGG----------------LGSGGCAGFLGNENGLLSGNEKVTMQNLNDRLASYLENVKA
LEEANADLEQKIKGWYEKYGP-GSCRGLDHD---YS-RYFSIIEDLKNEIISATACNANV
VLQNDNARLTA-DDFRLKYENELALHQSVEADINGLRRVLDELTLCTTDLEIQYETFSEE
LTFLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--WFNEKSATLQQQISDDVGATTAARNELTELKRSLQ
TLEIELQSLMAM----KHSYECSLAETEGNYCLQLSQIQDQIGALEDQLQQIRMETEGQK
LEYDHLLDIKIYLEKEIETYCCLIDGEERDCKSTCQKSKSYETAKPGNQVK-DSAQSTVV
KTVVEERDSNGPVLSVKVHSVEEKSSKISNITM--EQRVPSKAP------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MSVK--GGG
SSGGSAGGSYGSGGGSHTASGGSSR-RISSTGISSGGI--SGGG-TSGGGISS-GGLSSG
-----------GVSGGGGSSSGGGVRITS-------SSSSSRGYS-GRSYGGGGSRSGGF
SSGSAG--RISRGRVYGGSSYGGGSYGGGS---YGGGYGG---GGY-GGVSYGSGGG---
----YSSGSFSGGSYGGG-----GYGGGYYPF-----------------RR--GSF--GM
GGGDGGLLSNNEKSTMQNLNDRLAAYMNKVKYLEDENAQLE---VLIREWYQKHGDVG--
T--V-RDYTHHYQEIDQLFNELVNETDDYN------------KILLNIDNTRM-TAEDFQ
I-KY-QTEAGLRQNVEADINGLRPMLDQLTLARSDLEAQFESAKEELITLKKNHQE----
-ALRELQSQRGHGDINVEVNAAPGPDVKQRLDQLRAEYEAIIDN-NRREVE---QWFESK
----------------MEEVR-QQVSSSGLE--ISSGNQQVTDLRRQYQ---TLEIELQS
ALSMI---QSLQSNLEDTERRYNLQLQQIQSMIQPV-EGELASLRGEIESQ--SQEYQSL
LGIKTRLEQEIA----QYRQLLDEGQQEIGSGGG--------------------------
----------------------------GG-YGGGYGGGYGGG--RRGSIGR---IGGG-
--------------GMSSGGMSSGG---MSGGGM---S--SGTISGGG---M--------
-SGGM---SGGG----------------------MSSSG-------------------IS
-GG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------G----------------
-----------------IS-GGSMSGG--------------GL-------SSG--S-MSG
GGMSGGS-------------I-------SSGGKMS----GSMSS----SGM---------
------SSGGVIGGGSIGSGGGGSQIGG--------------------------------
------G--GGS--------------------SRHGRKSFD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVCTSALSRRSSS---Q-N----GAAGR--
---------------PWGASAS--SV-ASG-----YGGS----ASGFGV---G-----C-
GGLFSA-A---SM--FGSS---SGFSGGSA------------------------------
-------------SCL---PGLGSAYGGPLRGGAGGM-----------------------
-------------------------------GIGMGI---AGSSG----G--GSL--CIF
SGNDGGLLSGSEKETMQNLNDRLASYLGKVRSLEEANAELE---NKIREWYETRRT--GD
AGSQ-SDYSKYYPLIEDLKNKITSARVSNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQTVEADINGLRRVLDELTLTRADLEAQLETLTEELAYMKKNHEE----
-ELQSFQAGG-PGEVNVEMDAAPGVDLTKVLNEMRAQYEAVAEQ-NRKDAE---AWFLEK
----------------SGELR-KEISSNTEQ--LQSSKSEVTDLKRMVQ---NLEIELQS
QLAMK---SSLEGSLAETEGGYCCQLSQVQQLIGSL-EEQLQQVRADAERQ--NADHQRL
LGVKARLEMEIE----TYRRLLEGDSQGDGFDESS---SLSVSKP---------------
---------------------------------------QTPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVQELEEEM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSSSSKQFSS---SRS----GGGGG--
-------------------G-GGGSVRVSSTRGS-------------LGGGYS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG--------------------FG---
-----------------------------GGGSFGGGYG-------------GSSFGGGY
GGSSFGGGSFGGGGSFGG----G-----SFGG--GSY--------------GGGFGGGGF
GGDGGSLLSGNEKVTMQNLNDRLASYMDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYKTIEDLKGQILTLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVTLRQSVEADINGLRRVLDELTLSKSDLEMQIESLNEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEK-NRKDAE---EWFNQK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLSETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLEGEGSS--GGGGRGGGSHG-------------------
--------------GSYGG----------SSGGGSYGGGSSGGG-SYGGS----------
----S----------GGGGSYGGGSSGGGSHGGSSGGGYGGGSSSGGA------------
---GGHGGSSGGGYGG-GSSS----------------------GGQGGSGGFKSS---G-
GGD---QSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-FLQNSS-------ASYGG-----GSCKL------
-----------------GG--------------GRSISSSSTRFCSGGSAGGFG------
------------GG------I-SCGFGGGAGSGLGGGFGG------GLGG---GSFGGCF
GGGFG-DFGGGYGGGLGG----------------------------------------SL
GGGDGGLLSGNEKITMQNLNSRLASYLEKVRTLEEANADLE---VKIRDWHLKKSPTS--
---PERDYSSYFKTIEDLRDKILAATIDNN------------RIILEIDNSRL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLMKTDLEMQIESLNEELAYLKKNHEE----
-EMKELRNQV-IGQVNVEMDATPGIDLSRVLAEMREQYEAMAEK-NRRDAE---EWFNSK
----------------SEELA-KEVSSSTAS--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTVSETECRYALQLQQIQGFISSI-EAQLSELRSEMECQ--SQEYKML
LDIKARLEQEIA----TYRSLLEGQDAKL-PGFPAGGTISTSSTTSTR------------
--------------------------------------------------------RIS-
------EK--TRP-----------------------------------------------
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--------------------------------------------------

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--------------------------MTTSIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-TLGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYYRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLYGG---G-TSFGTGNSCGI-SGIGSGF-SSAFGGS-SSGGN
T------------------GGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DPAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSTRFVSGGSAGGYG------
------------GG------V-TCGFGGGAGSGFGGGYGG--------------------
------GLGGGFGGGFAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYHKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMRAQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEDQDAKM-TGVPSSAGSVSPRSTSVTTT----------
-------S------SVS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
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-------------------------------------------------M-----ALRCP
SGSRHRGLYSG--AGSIRPANR---G-TGLVSSGSCGS-AVFGSPF-SCALGGGLG----
----GVPGGNPGGGG----SG-HACTSFAGSEGGLLSGSEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKSWYDTYGP-GSCRGLDQD---YS-SLHLTIEDLKAKIISSTAANARV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCKTDQELQYESLSEE
ASYLKR--NHEE----------------------DMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAQQNHSDAEA--WFSEKSASLQQQMSHDAGKATRARTELTELKRTLQ
TQEIELRSLLAT----KHSLECSLSETEGNYCTQLAQIQVQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYRRLIDRDEG----SCSKSEGFGSGSSGHSPK-DLPKTTLV
KTVVEELDQGGKVLSSRIYSIEEKTLTLINKT---DQRVPF---------

------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGAGNTCIV-PGIGSGFSSCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRT
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTMKEKSTKV-NNKN--EQRVPS---------

------------------------------------------------------------
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-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFVAGNVCVG-SGAGSSF-SCTLGGISS----
----GGSFC-SSGGG----LGSGARTGFLGNEHSLLSGNEKVTMQNLNDRLASYLNHVRA
LEEANADLEQKIKGWYEKCEP-GSFRGHNHD---YS-RYFSVIEDLKRQIISATTCNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTNGLRRVLDELTLCTTDLEIQCETLSEE
LTYLKK--NHEE----------------------EMEVLQCTAGGNVNVEMNATPGVDLT
LLLNNMRAEYEALAEQNCKDAEA--WFNERSATLQQQISNDEGAATAARNELTEVKRNLQ
TLEIELQSLMAV----KHSYECSLAETEENYCNQLQQIQDQIGLMEEQLQQIRTETEGQK
LEYEQLLDVKIFLEKEIEIYCNLLDGEERKSKSTCYKSKGCRPVNSGNQGK-DSAKETIV
KTVVEELDQIGSVLSLRVHSVEEKSSKISNITV--EQRVPFKAP------

------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLG--------SVRLSSA---G-AGFGAGSACGV-PGMGSGF-SCAFGGSSSAGGY
G------------------VGSASCGAFTANEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIISATASNANI
VLQNDNARLTA-DDFRLKYENELALHQSVEGDINGLRRVLDELTLCRTDLEVQLETLTEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIDGDEGSCVKS----K--GQGGPGNQTK-DSSKTAIV
KTVVEELDPRGKVLSSRVHTLEEKATKINKNE----Q-RVPS--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
---------------YGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHCYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGRVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSE------------GLELELQS
QLSMK---AALEDTLAETEACFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHH-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRNISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSAFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTTEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLEHSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGGS------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
SGSRHICLRSG--TESVRPSSG---G-TGFAGSNVYGN-SGAGCGF-SYALGGGLG----
----SLPGGDHAGGI----PGSGTCVGFAGSEGGLFSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKSWYEKHGP-GSCHGLDHD---YS-RYHLTIEDLKNKIISSTTANANV
ILQIDNARLAA-DDFRLKYENELALHQNTEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EVKALQCVAGGNVNVEMNAAPGVDLT
LLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISDDAGAASSARGELTEMKRTVQ
TLDIELQSLLAT----KHSLECSLMETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDRNSCS----KSKGFGSGSPGNSSK-DLSRTTLV
KTVVEEIDQRGKVLSSRVQSIEEKTSKMTNGKT--KQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATTIRQFTSS-SSIKG--------SSGLG----
----G-----------------------GSR------------------TSCRLS-----
---------------GSLGG----------GSCQL-------GFA-----SGLG------
--------STLGASALGGSSSFSGCYSFGSGGGYSS--------------G---------
---------------YGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPRP--
---A-PNYNHYYQTIEDLKNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMNSLRSQV-GGDINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTLQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLPQY----------------------------
------KPREPVTTRQVRTI----VE------------ELQDG--RVISSQEKVH-----
----------------------------------QTTH----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MASTTSIRQFSTS-GSVKG--------LCAPG----
----M-----------------GFS-RMSSVR--------------IGGA-CRAP-----
---------------SLLGG----------GSCSNMSV-TSSRFS-----AGLG------
--------GSYG-------G----GYTCSLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGSEKETMQNLNDRLATYLDRVRALEEANTDLE---VKIREWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIETLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSM-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------ASQ
A-----SREGTVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

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-----------------------------------LSGNEKVTMQNLNDRLASYLDKVRA
LEEANADLEVKIKGWYETYGP-GSCRGLSRD---YS-GFHLTIEDLKAKITSSTAANTNV
TLQIDNARLAA-ADFRLKYENELSLHQNVEADINGLRRVLDELTLCRTDRELQYESLSEE
ATYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLSNMRAEYEALAEQNRRDAEA--WFSEKSASLKQQLSQDTGEATQARTELSELKRTLQ
TQEIELRSLLAT----KHSLECSLSETEGHYCSQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLNVKVHLEKEIETYCRLIDGDEGSCS----KSKGFGSGNSGNSSK-DFPKITLV
KTVLEELDQRSKVLSSRIHSIEEKTPKVTTIMK---QRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGLGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYG---------------GLSV-TSSRFSSGGA-CGMG------
--------GGYGGGF----SSS--SF--------GG--------------GLGGGLGVGF
GG----GYGGGFGGGISV-----GFGVG--------------------------------
---DGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---S-KDYSPYFKTIEELRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLSRADLEMQIETLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLQQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
C-------------------------RFQSSS-------TSYGG-GFGAGSCQL------
-----------------GG--------------GRKISTCSSRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGG------------------------
--GFGGSYGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLANYLEKVRALEAANADLE---VKIRDWHLRQSPAS--
---PERDYSAYYKTIEELRVKILEATTDNN------------RIILEVDNARL-AADDFR
L-KY-ETELNMRQSVEADINGLRRVLDDLTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFQSK
----------------SAELN-KEVSSSAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGFNNAGGNVTTTASASVSP----------
-------S------TSG-RV---------------------------------DFRKY--
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------VD----------------------FPGKAMS---------
-----------------------------LSMRSSGLSQRLSS---Q-S----GTAGR--
---------------TWGMSTS--GA-GSI-----YGGS----PFGFGG---S-----Y-
GGGFPA-A---SM--FGSG---SGFGGGSA------------------------------
------------SSSA---GGLGTGYGGSPG-----------------------------
---------------------------GAFVGLGAGF---RGGSG----G--GSA--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYEARGSGVVD
PKSQ-SDYSKYYMLIEDLRNKIISANVGNA------------QLILQIDNARL-AADDFR
M-KY-ENELALYQSVEADINGLRRVLDELTLARADLEMQIENLNEELAYLKKNHEE----
-ELQSFREDS-PGQVNVEMDATPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFAEK
----------------SGELR-KEISTNKEQ--LQSSKSEVTELKRAFQ---NLEIELQS
QLAVK---KSLEDSLAETEGDYCGQLDQVQQLITCV-EEQLLQVRADAERQ--SADYQRL
LNVKARLELEIE----TYRRLLDGEAA---------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSRS-------TRVSS---S-------RAGGSS
---------------SARVSAAGSSF-SGGSRCGLGGSS----ARGFRGGT-G-----G-
----------------------CGLSGGSSSAFRGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSS---GG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEELRNQNIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQVSAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCL-------SGVSS---F-------R--A--
---------------------------GGSRMSTGGSSS----AWGFQGGA-G-----S-
----------------------CGLSGGFSGGFGGG-------------------TGGGF
GSCSIE--GRWGAGSG-----SGAGFGGGSG-----------------------------
---------FG------G---ASGFSSGASGG----FCSYGGG-------TGGGFG-G--
GSGDAGLLPGNEKQTMQNLNDRLASYLGKVRALEEANTDLE---NKIKEWYDKFGPGSRD
GGTR-RDYSHYYSILEDLRKQITAATTENA------------RTMLQTDNARL-AADDFR
L-KY-EHELSLRQGVEADINGLRRVLDELTLSKTDLEMQIEGLTKELAYLKRNHEE----
-EMKSVQGSS-GGNVTVQVNAAPGVDLTKLLNDVRAQYEQLAEQ-NRREVE---ERYNEQ
----------------SASFQ-AQISTNAGA--ASSAKTEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADAEVGYVAQLSGIQMKIGSL-EEQICQIRRETECQ--NREYEVL
LDIKTRLEREIE----TYRRLLNGERGGSG-FERSED-----------------------
-----------------------------------------------------------L
V-----------------------------------------------------------
---------------------------------------------------TGNSR----
S----ESQGRDPNK-------T-----------------RVTK-----------------
---------------TIIEEVVDGRVVSSQVSSI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSTRFVSGGSAGGYG------
------------GG------V-TCGFGGGAGSGFGGGYGG--------------------
------GLGGGFGGGYAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVSALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYHKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGVPSSAGSVSPRSTSVTTT----------
-------S------SVS-ATTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRVSS---S-------RAGGSS
---------------SARVSAGGSSF-SSRSRCALGGSL----AWGFQGGA-G-----S-
----------------------CGLSGGSSGAFGGS-------------------FGGGF
GSCSVG--GGLGGPSG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSGGAGGG----FCSYGGG-------M----G-G--
GVGDGRLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKFGPGSGD
SGSG-RDYSKYHPTIEDLRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQSVEADINGLRKVLDGLTMTRSDLEIQIESLTEELVYLKKNHEE----
-EMKIMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELRRTLQ---ALEIELQS
QLAMK---NSLEGTLADTEAGYVAQLSEIQMQISAL-EEQICQIRGETECQ--NAEYAQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAGFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQERDS---SK----T-----------------RITK-----------------
---------------TIVEELVDGKVVSSQVSSI----SEVKL---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYTS--KQYSS---SRS----GGGG---
--------------------GGGSAHRISSSKGS-------------LGGGFS-----S-
-GGFSS-S---SF--SRGSSSGGCFGGSSG-GYGG---------------------LG--
-G-------GYGGGSF---GG--GGYGGG---SFGGGYG-------------GGSYG---
-GGSFGGGSFGGG-SFGG----G------------GY--------------GGGFG-GGL
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHSNT--S
RGER-RDYSKYYDTIDDLKNQILSLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLNKSDLEMQIESLSEELQYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLADK-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKTEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NSEYQVL
LDIKIRLENEIQ----TYRSLLEGEGSGGGHGGGRGGG----------------------
---------------SYGGSHGGS---SGG--------GHGG-G-SYG------GSHGGS
SGGGHGG-----------------GSFGGSHGGSSGGGHGGGSFGGS-HSGG----HGGS
SGGGHSGSFGGGSSGG-GSSG----------------------GGQGGSGGFKSSSS-GS
PGE---S-SKGPRSGESSWGNQ-----------------NQF------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSHS-------TRVSS---S-------RAGGSS
---------------SARVSAGGSSF-SGGSRCGLGGSS----ARGFRGGT-G-----G-
----------------------CGLSGGSSSAFGDS-------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---GSGFSSGASGG----LYSYGGG-------T----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKHGPGSGD
GGSG-RDYSKYYSIIEELRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EVKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRVQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQISAL-EEEICQIRGETKCQ--NAEYEQL
LDVKTRLEMEIE----TYCRLLDGEGGCS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYGG---------------LSV-SSSRFSSGGA-CGMG------
--------SSYGGGF----SS--SSFG-GYGGGIGC--------------GIGGGFGGGF
GGGFG------------G-----GLGG---------------------------------
---GDGLLVGSEKVTMQNLNDRLASYLDKVRALEQANTDLE---VKIRDWYQRQRPAE--
---I-KDYSSYFRTIEDLKSKIIAATLENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLESSLEETKGRYCMQLAQIQGLISGV-EEQLAQLRCEMEQQ--SQEYNIL
LDVKTRLEQEIA----TYRRLLDGEDAQISSSQH-SSGHSYSSREREV--FS--------
-----------SSSRQPRSIL---KE------------QGS---------SSFSQSQSQ-
------SSRN--------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYG---------------GLSV-STSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSYG----GGFGG--------------GYGGGLGAGF
GGGL-G-------GGFGG-----GLGGG------------------------------F-
GGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRTEVTELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQGLIGSV-EEQLAQIRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-TSGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QSSSSFSQGQSS-
------K-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSVLYSSSSKQFSS---SRS----GGG----
--------------------GGGGSVRVSSTRGS-------------LGGGYS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG--------------------FG---
-----------------------------GGGSFGGGYG-------------GSSFGGGY
GGSSFGGGSFGGGGSFGG----G-----SFGG--GSY--------------GGGFGGGGF
GGDGGSLLSGNEKVTMQNLNDRLASYMDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYKTIEDLKGQILTLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVTLRQSVEADINGLRRVLDELTLSKSDLEMQIESLNEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEK-NRKDAE---EWFNQK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLEGEGSSSGGGGGRGGGSHG-------------------
--------------GSYGG----------SSGGGSYGGSSGGGG-SYGGS----------
----S----------GGGGSYGGGSSGGGSHGGSSGGGYGGGSSSGGA------------
---GGHGGSSGGGYGG-GSSS----------------------GGQGGSGGFKSS---G-
GGD---QSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MS-TYYQSSS-SSHGG----------GMGFG--
GG--G-----------------GSS-RLSSG--------------------GFG------
---------------G-SG--------------GGRMSSSSVRYVSSGG--GHG------
------------GG------Y-GGSLGGGYGSGFISGGGV------GLASGFGGGAGGGY
GGGAGGGYGGGFGGGFGG-----GYGG----G-----------------GFGSCFD--FA
AGGDGVLLAGNEKVTMQNLNDRLATYLDKVRALEEANTELE---VKIRDWHQKQAPKS--
---PSRDYSQYYKIIEDLRDKILGTTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELHLRQSVEADINGLRRVLDELTMSKSDLEMQIEGLKEDLAYLNKNHEE----
-LMKEFSTQL-TGKVSVEMDAAPGIDLTKILADMREQYEHLAEQ-NRKDAE---TWFFSK
----------------TEELN-REVATNTEQ--IQTSKSEISELRRTIQ---GLEIELQS
QLSMK---AGLESNLAETEGRYCAQLAQIQNLITGV-EEQLAELRNDMERQ--NQEYKML
MDIKTRLEQEIA----TYRNLLEGQDSKL-STWSPKDGT---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFP
GGSRHNCLRAG--TGSVRPPSG---G-AGFAGSNACGS-SVAGSGF-SCTLGGGLG----
----GVPSGSHASGA----LGNAAGMGFVGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKTWYEKYGP-GSCRGLDHD---YS-RYHLTIEELKNKLISSTTANANV
ILQIDNARLAA-DDFRLKYENELALHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGHVSVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSATLQQQISDDAGAATSARNELTEMKRTLQ
TLEIELQSLLAT----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVISSRVHSIEEKTSKVTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSTRFVSGGSAGGYG------
------------GG------V-TCGFGGGAGSGFGGGYGG--------------------
------GLGGGFGGGYAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYHKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGVPSSAGSVSPRSTSVTTT----------
-------S------SVS-ATTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------RTTV-KPAESFPAATMSCGSKQTSR-SCHR------------------
---------------------------GSSASSRRYTARTSSGG-RFSGGS-C-GGGSSS
-----------CYGG--------AASGGSYGRIRH------------CSYGGGMSGG---
-----S--CRGG---------------------GGGGYFG---GGM-SGGSYGGMSGGGY
G-G-----GMRRGSM-GG-----GFGSAR-------------------------------
SGWSMGILSNDEKLTMQNLNDRLASYLDTVRNLEKENAQLE---QLIREWYQKQGPTG--
---R-KDYSHYYGEIEDLQNQLVTAAVETN------------KILLDLDNTRM-TAEDFR
I-KY-ETEYGLRQNVEADINTLRPLLDNLTLSRSDLEMQFESLKEEMIGLKKNHEE----
-EIKSLQTQS-GGDVNVEVNAAPGEDLLKKLNDMRQEYEHIIQK-NREEVE---RWYESK
----------------MEEVS-QQVHSSGQE--LESSTQQISALRRDYQ---SLEIELQS
QLSMV---RSLQSNLEDTERRYNMQLQQIQSMISPL-EEELASIRCEMESQ--NQEYKML
LGIKTRLEQEIA----QYRALLQEGQHGIGSS----------------------------
-------------------------QGGGG-GGGSSGGGGHGG--INWSSGRGSSGGGR-
--------------SWSSGGGSSGG---RTG----------------G---S--------
-CG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----K-----------------------ASRYTS----SGGSGG----------------
-----------------FS-GRSF-GG--------------GG-------SRS--S-YGG
GFSSGSCG--RIGRSSYGGRIS---S-GSYGGGMG----GSMGGGFGSV---------PA
GGMGGGMGGGRIGGGSYSGGGRGGSAGGVSS-------SHSYSSSSQS------------
-QACR-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------LGTMTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-SSSRYSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGGLGSGFGG--------------GYGGGLGAGF
GG----GFG----GGLGA-----GFGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADTNGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDLIGNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHYGGGSSSGGGSG------GN--YGGGSSSGG-
--------G--SGGKGGSGGS---YG------------GGGSG--GSYGG--GSS-----
---------SGGGSGGSYGGGSSSGGGSG-GRRGSGGSYGGGISSGGGSRGS--------
-YGGG---SSSGGGSG-GRGGSG----------GSYGGGSS-T----GGGSGSSYGGGSS
SGG---GSGS--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLP
SGSRRASPRP--TTGSLRLSSG---G-ASFGAGNACSM-PGIGSSF-SCAFGGSS-SGGN
A------------------LGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQITEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYGAGNVGNQMK-DPVKAIVV
KKVLEEVDQRSKILTPRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MS
C-------------------------RMQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSSGGYG------
------------GG------I-SCGFGGGAGSAFGGGCGS------G------------F
GGGFGGGFGGSFGGGFGS-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWHLKQSPSS--
---PERDYSHYYKTIEELRDKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFNQR
----------------SAELN-KEVTSSTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLEGTVAETECRYAMQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFTSSAGSSSSTVNASTT-----------
-------------------------------------------------------RRPS-
-------ETNRRN-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQSSATSSFGG----------L------
-G-------------------------GGSVR-------FGAGG-AYRAPSIHG------
---------------G-SG--------------GRGVSVSSARLVSS-SSGG--------
------------------------------------------------------------
-----------YGGGYTG-----GFVS----T--------------------------L-
-AGSDGLLVGNEKTTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYFKTIEDLRDKILSATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVNVEVDSAPGIDLAKVLSDMRSQYEVMAEK-NRKDVE---TLFITQ
----------------MDTLN-QEVISHKEQ--LEIKKSEVTDLRRTLQ---GLEIELQS
HLSMK---AALEGTLAETEARYGAQLAQIQALISSL-EAQLGDVRAESERQ--NQDYQRL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTSKV---V------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----AGF
GG--------GLGAGLGG-----GFGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SASRRAGPWPTT--GSLRLSGG---G-ASFGAGNTCSI-PGIGNGF-SCAFGGS-SSGGN
A------------------AGSNSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVETDVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
LLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGNQVK-DPAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SSSRRVGSCGG--AGSVRLPSG---G-AGFGVGSTCGM-PGIGSGF-SCAFGGNSSGGGY
GLG----------------GGSSSYATLLGNEAGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKYGP-GSCRGLDHD---YS-RYFPIIEDLKNKVISATTSNANV
VLQNDNARLTA-DDFRLKYETELALHQSVEADINGLRRVLDELTLCRTDLEIQAETLNEE
LTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
ILLNNMRAEYEDLAEQNRRDAEA--WFNEKSATLQQQISDDAGATTSARSELTEMKRTVQ
TLEIELQSLLAT----KHSLECSLTETEGNYCVQLSQIQAQIGALEEQLQQVRTETEGQK
LEYEHLLDIKVYLEKEIGTYCSLIDGEDGDCYKS---KAGFASGGSGNQIK-DSSKTTVV
KTLVEEIDPRGKVLSSRVHSVEEKSSKINTIKT--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGP---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-NDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDF R
M--------------------------------------IESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLATK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQSSS-------TSYGG-GFGGGSCQL------
-----------------GG--------------GRSFSSCSTRFASGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
----SGGFGGGFG-GSYG-----GFG--------------------------------DF
GSGEGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQRQSPAS--
---PERDYSAYYKTIDELRAKILAATTENN------------RVILEVDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFGKQV-VGQVTVEMDAAPSVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFQSK
----------------SAELN-KEVASNTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQGLVSSI-EVQLGELRSETECQ--SQEYKIL
LDIKTRLEQEIA----TYRSLLEGQDSRL-TVSASPAGSGSYSVGTTSNV----------
-------S----------GSVS----------------GSV---------SGSFP-----
------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
SRSKHICLRPG--TGSVRPPSG---G-A-------------AGSGF-ACALGGGLG----
----SVPGGSHVAGA----LGNAACVGFAGNEGRLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCHGLDHD---YS-RYHLTIEDLKNKIISSTTANANV
LLQIDNARLAA-DDFRLKYENELSLHQTVDADINGLRRVLDELTLCRTDQELQFESLSEE
MTYLKN--SHEE----------------------EVKALQCAAGGNVNVEMNAAPGVDLT
ILLNNMRAEYEDLAEQNRRDAGA--WFNEKSAILQQQISDDAGAATSARNELIEMNRSLQ
TLEIQLQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTKTEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGNSGDASK-DLSKTTLV
RMVVEEIDQRGKVLSSRVQSIEEMTSKMTNGKK--EQRILF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATAFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGVGGGYG------
------------GG------M-SCGFGGG----------------------TG-------
-GGFGGGFGSGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PEQDYSHYFKTMEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-EHELSLRQAVEADINGLRRVLDELTLARTDLEMQIENLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQSSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGLISGL-ETQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRNLLEGQDAKM-AGIGIREASL---GGGGGGA----------
-------SSSSSSSSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRSGTRPS--TGSLRLSSG---A-AGFGAGNACGL-PGIGSGF-SCAFGGSA-SGGN
A------------------GTGNPCAGFTMNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KQSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDLKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNMGNQIK-DPAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MSYSVQKSS----LWQFS------------
------------------------------------------------------------
---------------------SGQGRGGSIR-----------------------------
-----------------K---KHGPG-GTSGG---VFSSTFGGY-------------T-F
GGRENGLLSGNEKGTMQNLNDRLAIYLDKVRALEEANTELE---YKIKEWYKKFGPGSTS
HGEN-RDYSEYYQIIEELKQKILDSSLSNT------------DIMLQVDNVRL-AADDFR
L-KY-ETELALRQSVESDINGLRRVLDDLTLAKTDLEMQIETLSEEVAYLKKNHAE----
-EMKGLQKAT-SSDVNVEMNAAPGTDLTKYLHDMRAQYEALAEQ-NRKDVE---TWFNDK
----------------SEVLQ-QQISFANDE--SNSAKTEISELKRTSQ---TLEIELQS
ALALK---KSLEGSLSETEAGYGTQLSHTQNQISSL-EAQLIQIRDEAENQ--STEYKQL
LDIKTRLENEIE----TYRRLLDEEGGAGLE-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----NRAKKESTK-------T-----------------F--------------------
------------LYKTIVEELVDGIVVSSKIKNVHQRSA---------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
SASRRLG--------SVRLSSA---G-TALGAGNACGV-PGIGSGF-SCAFGGSTSAGGL
G------------------LGSASCGAFTTNEHGLLSGNEKVTMQNLNDRLASYLENVQA
LEEANADLEQKIKDWYEKFGP-GSCRGLDND---YS-IYFPIIDDLRSQIISATANNANI
VLQNDNARLTA-DDFKMKYENELALHQSVEADINGLRRVLDELTLCRTDLEVQLETLTEE
LAYLKK--NHAE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCRLIDGDEGSCVKS----K----GGPGNQTK-DSSKTAIV
KTVVEELDPRGKVLSSRVHTLEEKSTKVNKNE----QR------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------TSCS-------SRISS---S-------RAG---
---------------SSRVSAGRSSV-SSGSRCGLGGGS----ARGFQGGT-G-----N-
----------------------CGLSGGPSSGF-----------------------GGGF
GSCSVR--GGLGATLG-----SGSCFGG--------------------------------
---------------------GSGFSSGDNRG----FYSHGGG-------MGGCLS-G--
GLGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKAWYDKFGPGSGK
DGSG-RDYSKYYSIIEDLRNQIITATVENA------------GTILQIDNARL-AADDFR
L-KY-ENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQTESLTEELTYLKKSHEE----
-EMKSVQGSS-GGDVTVQMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SAALQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAM--------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSLR-------LGAGS-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SSGG--------
------------------------------------------------------------
-----------YGGGYGG-----TFGS----S--------------------------F-
GARSDGLLAGNEKLTMQNLNDRLASYLDKVRALEEANGDLE---VKIRDWYQKQGP-G--
---PAHDYSHYFKTIEELREKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQAMRMSVEADINGLRRVLDELTLAKSDLEIQIESLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGIDLAKILGDMRSQYEVMAEK-NRKDAE---AWFISR
----------------TEELN-REVAGNTEQ--LQISKSEVTDLRRTLQ---GLEIELQS
QLSMK---AALESTLAETEARFGVQLAQIQTLISTL-EAQLSEVRADTERQ--NQEYQQL
MDVKSRLEQEIA----TYRSLLEGQDAQY-NNLPTPKA---L------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGS---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-NDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSVRFSSNSRQYSS---ARS----GGGGG-G
-------------------GGGGSSIRVSSTKSS-------------LGGGYS-----S-
-GGFSG-G---SF--SRGSSSGGCFGGSSG-GYGG---------------------FG--
-GGSFG--GGYGGGSF---GG---GYGGG---SFGGGYG-------------GGSFG---
-GG-YGGGSFGGG-SFGG----GSFGG-------------------------GSFG-GGL
GGDGGGLLSGNEKVTMQNLNDRLASYMNKVRDLEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYKTIEDLKGQIVNLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLSKADLEMQIESLTEELAYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEK-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKTRLENEIQ----TYRSLLEGEGGYVGNLQITLNCFPSEFHLA--KLTQTQG-----
------------KTRGWKGSNTNK---TRVIKT-IIEEVTPE-G-RVLSSMIESETKKHF
Y-----------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SSSRRLG--------SVRLSGG---E-ASFGAGNAFGV-PGIGSGF-SCAFGGSSAAGGY
GGV----------LG----GGSASCATFTRNENGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRNQIIAATTSNANV
ILQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEVQLETLTEE
LAYLKK--NHEE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLGNMRAEYEALAEQNRQDAEA--WFQEKSASLQQQISDDAGATTSARNELTELKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLMDVKAHLEKEIETYCRLIDGDDESCVKS----K--GHGGPGNQIK-DSSKTAIV
KTVVEELDLRGKILSSRVHTIEEKPTKP-NNKS--EQRVPS---------

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-------------------------------------------------M-----SLRLS
SGSRRSYARPSTGS--L----R---G-TSFGAGNACGV-PGIGSGF-SCAFGGSS-SGGN
T------------------GVGSSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQFETLSEE
LTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSASYKSKDYGSGNAGSQIK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MACS-------SRVSS---S-------RAGGSS
---------------SFKMSAGGSSF-SSGSRCGLGGGS----ARSFRGGA-S-----S-
----------------------CGLGGGSGGGFGGS-------------------FGGGM
SSCSVG--GGFGGISS-----SGAGFGGSSG--YGGGY----------------GFGGG-
---------------------SSGFGGGASGG----FYGYGGG-------MGGGVG-G--
GMGDGGLFSGGEKQTMQNLNDRLASYLDKVRALEEANTDLE---NKIKEWYEKFGPGSRD
GKPG-RDYSKYYPVIEDLKNQIIKATIENA------------GILLQSDNARL-AADDFR
L-KY-ENELYLRQSVEADINGLRRVLDEMTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGTS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--TSSAKSEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTESRYMAQLSEMQMHISSL-EEQICQIRGETECQ--NAEYEQL
LDIKTRLEQEIE----TYRRLLDG EGGVTNLGGGKNGFSLLNKRNY--------T-----
------------K-KAK----F--------------------C----------------L
L-----------------------------------------------------------
---------------------------------------------------LHS------
-----SFYGRNYRNVSKILNFS-----------------RFQM-----------------
------QLAAVDLRQKFENELDLPQSVKADISRLCCILDDLDLSKTDLEIQIEALAEEFI
YLKKTHEDVCAQNKHNLPLSSLILVF---NSNLMRVRKAL--------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTANEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKATKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MATTTTVRQYSTS-GSMSG--------VCGLG----
----G-----------------GSS-RMSSVR--------------VGGA-CLAP-----
---------------SLLGA----------GSCGNMSV-TSSRFT-----SSLG------
--------SSYG-------GGYGSGYTCNLGGGFGS------------------------
---------------------------S------------------------------YS
--VGDALLGGSEKETMQNLNDRLASYLDKVRALEEANTDLE---LKIRDWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SLVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKRNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSSKTEITELRRTVQ---NLEIELQS
QLSMK---ASLEGTLAETEARYGAQLAQLQGMISSI-EQQLCELRCDMERQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLASQYSS-AL-------------------SSQ
S-----GRDAMVTSRQVRTI----VE------------EVQDG--KIVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-S-SRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGGGLGAGF
GGGL-G-------AGF---------GGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQQ-ASGQSYS--SREA--EITPS--H--
----------SSLGNRVRSCL---KN---------------------NSSLLYFSYLIA-
------LHVFSTVSCSCFKMQ---------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
-------------------------------------------------M-----SLRIS
SGPRRICSWSG--AGSVRMPNG---S-TGFGNSNMCGA-SAVGSEL-TCALGSS-G----
----GAPSGIPIGGS----FGNASCAGFVGSE-GLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANSELEQKIKGWYEKFGP-GSCRGLDHD---YS-RYQLTIEELKNKLISSTTSNANV
VLQIDNARLAA-DDFRLXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX
XXXXXXXXXXXX----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--WFNEKSATLQQQISDDAGATTSARSELTEMKRTVQ
TLEIELQSLLAT----KHSLECSLSETEGNYCVQLSQIQAQIGALEEQLQQVRTEMEGQK
LEYEQLLDTKIRLEKEIETYCRLIDGDGS----SCSKTKGYGPGGPGNSTK-DLSKTTLV
KTVVEELDQRGKVLSTRV--IEEKSSKLSNGKA--EQRAPF---------

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFVAGNVCVG-SGAGSSF-SCTLGGISS----
----GGSFC-SSGGG----LGSGACTGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVRA
LEEANADLEQKIKGWYEKCEP-GSFRGHNHD---YS-RYFSVIEDLKRQIISATTCNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTSGLRRVLDELILCTTDLEIQCETLSEE
LTYLKK--NHEE----------------------EMEVLQCTAGGNVNVEMNATPGVDLT
LLLNNMRAEYEALAEQNCKDAEA--WFNERSATLQQQISNDEGAATAARNELTEVKRNLQ
TLEIELQSLMAV----KHSYECSLAETEENYCNQLQQIQNQIGVIKEQLQQIRTETEGQK
LEYEQLLDVKIFLEKEIEIYCNLLDGEERKSKSTCYKSKGCRPVNSGNQGK-DSAKETIV
KTVVEELDQIGSVLSLRVHSVEEKSSKISNITV--EQRVPSKAP------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSSF-SCALGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KRSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLDEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSHS-------TRVSS---S-------RAGGSS
---------------SARVSAGGSSF-SGGSRCGLRGSS----ARGFQGGT-G-----G-
----------------------CGLSGGSSSAFGGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGEVS----------------G-----
---------FGRGSGFCG---SSGFSSGASGG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSR-RDYSKYYSIIEELRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADINGLRKVLDDLTMTRSDLETQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQVSAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-SS-S---S----------TFGGC--
ST------------------------RGGSLR-------AGGGG-GFGGGSLYG------
---------------G-GG--------------SRGISASSARFVSSGLGGGYG------
------------GG------A-GCGFGGGAGGGFGG-------------G-FG-------
-G----GFGGGLGGGFGG-----GFG--------------------------------DF
GGGDGGLLTGNEKVTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQSPAS--
---PERDYSRYFKEIEELRDKILAGAIDNS------------RVILEIDNARL-AADDFR
L-KY-EHELNLRQTVEADINGLRRVLDELTLAKTDLEMQIESLNEELAFLKKNHEE----
-EMKEFGSQL-AGQVTVEMDAAPGVDLTRVLAEMREQYEAVAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEVTELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGLIGGL-EEQLAQLRCEMEQQ--SQEYNML
LDIKTRLEQEIA----TYRSLLEGQDARM-AGVGTR---EAVLGGGGSG-----------
-----------GGSSNFRIKVE----------------ESVDG--KV----------LS-
------S--HKRD---------------V-------------------------------
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-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFMAGNVCVG-SGAGSSF-SCTLGGISS----
----GGSFC-NSGGG----LGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHA
LEEANADLEQKIKGWYEKCEP-GSSREHDHD---YS-RYFSVIEDLKRQIISATICNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEE
LTYLKK--SHEE----------------------EMEVLQYTAGGNVNVEMNATPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--WFNERSATLQQQISDHEGAATAARNELTEIKRNLQ
TLEIELQSLMAV----KHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQK
LEYEQLLDVKIFLEKEIEIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAK-DSTEETIV
KTVVEELDQIGNLLSLRVHSVEEKSSKISNITV--EQRVPSKAP------

------------------------------------------------------------
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------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGTGNSCGI-SGIGSGF-SCAFGGS-SLGGN
T------------------AGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

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-------------------------------------------------M-----SLQFS
NGSRHVCLRSG--AGSVRPLNG---G-AGFAGSSACGG-SVAGSEI-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVELA
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDSGAATSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSPGNSSK-DLSKTTLV
KTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGAGNTCGV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKN--EQRVSS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MATTTSIRQYSSS-SSVKG--------LCAPG----
----G-----------------GLS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGNMSL-TSSRFS-----AGLG------
--------GGYG-------G----GYTCNLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGSEKETMQNLNDRLATYLDRVHALEEANTDLE---VKIRDWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLSRADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQLL
LDVKTRLEQEIA----TYRRLLEGEDTHLASQYSSS-M-------------------ASQ
P-----SREAMVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSNF-SCAFGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNNTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VI-GR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGT---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGACYGRA-----------------------
------------------------LGGGSFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTAD
A-SQ-SDYSKYYPLIEDLRNKIISASIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHED----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAFQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-----------------------MTATATSIRQISTS-GSVKG--------LCMPS----
----G-----------------GFS-R--------------------------MS-----
---------------SIRVG----------GACRA-------PSL-----LGVG------
--------SS------GNMSMSSSRFSMGLGGGYGG--------------GYTCN----L
GG------------GFGG-----GFG----------------------------------
--GVDGLLVGGEKATMQNLNDRLASYLDKVRALEEANTELE---LKIRDWYQKQAPGP--
---A-PDYSSYFKTIEDLRNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLRKNHEE----
-EMKALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTLQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHSLTQYKTKER--------------------KH
F-----GNRGPVTTRQVRTI----VE------------EVQDG--RVISSREQVH-----
----------------------------------QTTH----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------MATTTSIRQYSSS-SSVKG--------LCAPG----
----G-----------------GLS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGNMSL-TSSRFS-----AGLG------
--------GGYG-------G----GYTCNLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGSEKETMQNLNDRLATYLDRVHALEEANTDLE---VKIRDWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLSRADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQLL
LDVKTRLEQEIA----TYRRLLEGEDTHLASQYSSS-M-------------------ASQ
P-----SREAMVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
SGSRHICLRSG--TESLRPSSG---G-TGFAGSNAWGN-SGAERGF-SYALGGGLG----
----SLPGGDHAGGI----PGSGTCAGFAGSEGGLFSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKSWYEKHGP-GSCRGLDHD---YG-RYHLTIEDLKNKIISSTTANANV
ILQIDNARLAA-DDFRLKYENELALHQNTEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
LLLNNMRAEYEALAEQNRREAEA--WFNEKSASLQQQISDDAGAASSAQGELTEMKRTVQ
TLDIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDRNSCS----KSKGFESGSPGNSSK-DLSRTTLV
KTVVEEIDQRGKVLSSRVQSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYAS--SKYSS---SRS----GGG----
-------------------GGGGSSLRISSTKSS-------------HGGGYS-----S-
-GGFSG-G---SF--SRGSSSGGCFGGSSGGGYGG--------------------GLG--
-G-------GFGGSSF---GG-----------SFGGGYG-------------GGSSF---
-GGGFGGGSFGGG-GYGG----GGYGG-------------------------GYGG-GGY
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--S
QREP-RDYSKYYQTIDDLKNQILSLTTDNA------------NVLLQIDNARL-AADDFR
M-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESMTEELAYMKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDVE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKTEITELRRTVQ---GLEIELQS
QLALK---QSLESSLAETEGRYCMQLSQIQAQISAL-EEQLQQIRAETECQ--NSEYQML
LDIKIRLENEIQ----TYRSLLEGEGSSGGRGGGGGG-----------------------
-------------------------------HGGSYGGGSSG-G-GHGETLLLSRMERCL
FTQAILSDAGAKTSASVLMACGHRFTP---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQSSSTSSFGG----------LGGGL--
-G-------------------------GGSVR-------FGAGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SSAG--------
------------------------------------------------------------
-----------YGGGYGG-----GFAS----A--------------------------L-
-AGSDGLLAGNEKATMQNLNDRLASYLDKVRALETANGELE---VKIRDWYQKQGP-G--
---PFRDYSHYFKTIEDLREKILGATIENS------------RVVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIENLKEELAYMKKNHEE----
-EISVLRGQV-GGQVNVEVDSAPGIDLAKILSDMRSQYEVLAEQ-NRKDVE---TWYTGQ
----------------IDILN-KEVTSNKEQ--LQISKSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEAHFGAQLVQIQGLISAI-EGQLADLRADSERQ--NQDYQRL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NDLPTSKV---V------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYG---------------GLSV-SSSRFSSGGA-CGMG------
--------SSYGGGF----SSS-S-FGGGYGGGIGG--------------GIGGGFGGGF
GG--------GFGGGIGG-----GIGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPAE--
---I-KDYSSYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIETLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLSQIQEMISGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-STQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTVRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----SGLG------
------------S-ALGG-SGYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GADGLLAGNEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYKKQAPGP--
---A-RDYSQYYKTIEDLQNKILTASVDNA------------NIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELLYLRKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--RVISSREEVH-----
----------------------------------QSPR----------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--TGSVRLSSG---G-AGFGVGNTCGM-PAIGSGF-SCAFGGSSSVGGY
GGG----------LG----GGSVSCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIISATASNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHAE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSAQNELTEMKRTLQ
TVEIELQSLLAT----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGEDGSCSKS----K--GYRGSGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRIHTVEEKSTKV-N-KN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------STYG---------------GMS-----RFSSAGA-YAVG------
--------SGYGGGF----SSS--SFGGGFGGGIGG--------------GIGGGLGGGI
GGGFGGGIGGGFGGGIGS-----GFGGG------------------------------L-
---GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANSDLE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KF-ETEQSLRINVESDINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSS-AQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------SGSMR-------FGVGS-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSSSGG--------
------------------------------------------------------------
-----------YGGGYAG-----ALA----------------------------------
--GSDGLLAGNEKLTMQNLNDRLASYLEKVRALEEANGDLE---VKIRDWYQKQGP-G--
---PARDYSHYFKTIGALRDQILGATVENS------------RMVLQIDNARL-AADDFR
T-KF-ETEHALRVSVEADINGLRRLLDELTLARTDLEMQIENLKEELAYLKKNHEE----
-EISVLKGQV-GGHVSVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSQ
----------------TEELN-REVAGHTEQ--LQSSKTEVTDLRRTLQ---GLEIELQS
QISMK---AALDGTLAETEARFGAQLAQIQALISGV-EAQLSDVRADTERQ--NQEYQHL
MDIKSRLEQEIA----TYRNLLEGQDAYY-NDLSTPNV---L------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------IIFCSPLKLQ--------LPTDKA-SISHTTM-----SLRFS
SGSRHICLQSG--PGSVRPSSV---G-AGFAGSNACGN-SLTGSGF-SCTLAGGLG----
----S---GSHTNGA----VGNAACADFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGRD-P---YG-RYHLSIEDLKNKISSTTA-N-AS
VLQIDNARLAA-DDSRLKNENELVLHQNTEADINGLRRALDELTLCRNDQELQYGSLSEG
GAHLKRTLEEXX----------------------XXXXXXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXXXXXXXX--XXXXXSATLQQQISDDVGAATSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LECEQLLDIKVHLEKEIETYCRLIDGEEV----SCSKSKVVGS---GNSPK-ELAKTTLV
KTVVEEIDQRGKVLSSRVHSNEKKPSKMTNS-A--EQRAPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTYSYRQ----SSATS----------SFGGL--
-G-------------------------SGSLR-------FGAGG-TIRAPSIHG------
---------------G-SG--------------GRGVSVSSASFVTSSSSGS--------
------------------------------------------------------------
-----------YGGGYAG-----TLA----------------------------------
--GSDGLPAGNEKETMQNLNDRLASYLDMVRALEQANGDLE---VKIRDWYLKQGP-G--
---PARDYSHYFKTIEELRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLKMQIEGLKEELAYLKKNHEE----
-EISVLRGQ-----VTVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTTK
----------------TEELN-REVAGHTEQ--LQINKTEITDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISSI-EAQLSDVRADTERQ--NQEYQLL
LDVKTRVEQEIA----TYRSLLEAQD----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQLTSS-SSVK------------------
---------------------------------------------VLSGSSCQ-------
----------------------------------A-----------SSAYGGLSVSC---
------------------------------------SPCC--------SSGGVCGLGGGY
GGGFSNSSSLG------G-----ALCGSLVGG-----------------YGGGLGV--GY
SGGDGSLLPDNEKITMQNLNGRLASYLGKVHALEEANRELE---TKTHDWYQSQGPRP--
---A-RDYSSYFKTIEDLRNKVECTAPS------------------ADDNARL-AADDFR
T-KY-EHELTLCQRVEADINGLHRVLDELTLARTDLEMQVEGLKEELAYLKKNHEE----
-EMLALQNQI-GGDVSVEMDAASSVDLSRVLNEMRDQYDSRQKL-QGRQALYTFCSFLSQ
----------------SEELN-KEAAFNSEL--MQKSHSELNELRRVLQ---GLEVELRS
QLCMK---ASLEKSLEETQHRYCLQLAQIQERISSV-EEQLAQLHCEMEPQ--NQEYKIL
LDVKAWLEQEIA----TYRRLLEGEDTHELSADESPRS----------------I-CHPC
PPIHPHNHRHLPFSLELGLLLFISPTLIST------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
SGSRHIRLWSG--TGSIRPSSG---S-SGFVGSNVCGS-SVAGSGF-SCALGGGLG----
----SVPGGNHASGV----LGNAACSGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYDKYGP-GSCRGLDHD---YS-RYHLIIEDLKNKIISSTTANANV
ILHIDNARLAA-DDFRLKYENELALHQNTEADINGLRRVLDELTLCRTDQELQYESLSEE
LRYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCAQLSQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGEDGSCV----KSKGYG--GPGNQIK-ESSKTTMV
KTIVEEIDPRGKVLSSRVHTVEEKSTKANNVKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSCSRQFTSS-S-MKG--------TCGIG----
----G-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYGG---------------LSV-SSSRFSSGGA-CGIG------
--------GGYGGGF----SSS-SGFGGALG-----------------------------
------------------------------------------------------------
----SALLSGNEKITMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQRPTE--
---V-KDYSPYFRTIEELRSKIISATLENA------------QPILQIDNARL-AADDFR
T-KY-EHELNLRQSVEADINGLRRVLDELTLARTDLEAQIEGLKEELAYMKKNHEE----
-EMLALRGQT-GGDISVEMDAAPGVDLSRILNEMRDQYERMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQGLIGGV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSSQQ--ASGQSYSSR--DV--FSSSS--S--
----------TSAARQTRPIL---KE------------Q---------GSVSFSQSQSQ-
------SQSSRN------------------------------------------------
------------------------------------------------------------
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--------------------------------------------LSSKAM-----SLRIS
TGPRRICSWSG--AGAVRIPNA---S-TSFGNNSMYGG-SVVGGGN-L--PGGSYGSCLS
GSSGGAPSGNPVVSS----FGSASGAGFVGNE-GLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANSELEQKIKGWYEKFGP-GSCRGLDHD---YS-RYQVTIEELKNKLISSTTSNANV
VLQIDNARLAA-DDFRLKFENELAFHQSVEADINGLRRVLDELTLCRTDLEIQYETMNEE
LTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSATLQQQISDDAGATTSARSELTEMKRTVQ
TLEIELQSLLAT----KQSLECSLRETEGNYCVQLSQIQNQIGALEEQLQQVRTETEGQK
LEYEQLLDTKIHLEKEIETYCRLIDGDGSSCS----KTKSYESGVPGSSIK-DLSKTTLV
KTVVEELDQRGKVLSTRVHSIEEKTTKMSNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------ITVTMSL---------R--------------------
---------------------SSSSY-SVQSKSVS-------------------------
--------------------------------GGGG-------------------FGSGY
GASFGG--GSFSGGSY-----GGSSF----GGGFGA------------------------
-----------------------GFGGGAASG----FSASSAGG----------FG-AAS
ASSSFSSFGGSDKQTMQNLNDRLAAYLEKVRALEAANADLE---LKIREWYEKQR-TSGI
GAGA-KDFSKYFDIITDLRSKILFATIDNS------------RVVLQIDNAKL-AADDFR
L-KF-ENELALRQSVEADINGLRRVLDELTLARGDLEMQIESLTEELAYLKKNHEE----
-EMSIAKSSA-AGQVTVEMDAAPGTDLTNILNNMRADYETLAEK-NRRDAE---LWFNQK
----------------SGELK-KEILTGVEL--VQSSKSEISDLRRSLQ---SLEIELQS
QLAMK---KSLEDSLAETDGRYGAQLQTIQLSIRSL-EEQLLQIRSDMERQ--NMEYKQL
LDIKTRLEMEIE----TYRRLLEGELSSSSSSV---------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------QVITS--QS
S----SSSKKDPSK-------T-----------------RKVK-----------------
---------------TIVEEVVDGKVVSSRVEEVEENVK---------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------STYGG---------------LSV-TSSRFSSGGA-CGMG------
--------GGYGGGF----SSS-SSFGGALGGGYIG--------------GL--------
----------------GA-----GFGSG------------------------------F-
GVGDGGLLSGNEKVTMQNLNDRLATYLDKVRALEEANADLE---VKIRDWYQRQRPNE--
---I-KDYSPYFRTIEDLRSKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELAMRQSVEADINGLRRVLDDLTLARADLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGNV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHPQRPPAPHSGQSYSSR--EG--KSP-------
------------GGSGMTPCH---LF------------LWVYA--ESLSSEPLVSSSGG-
------QLSSQSSTHLCFSFLQSSPRPHLHPLASPGPS----------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------------------DL----GMGGS----------EVFFGFF
LF-------------------------F-FFC-------L---C-------AFC------
---------------I-MK--------------RSSSCLSSSS-----------------
------------------------------------------------------------
------------LGGYSG-----V------------------------------------
LAASDRLLEGNEKLTMQNLNDRLASYLDKVCALEAANCELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLQDKFLGATIENS------------RIVLEIDNARL-AADNFR
T-KT-DTEQALRMTVEADINGLRRVLGELTLASTVLEMQIEGLKEELAYLKKNHEE----
-EISGLRGQV-GGQVSVEVDSARGTDLARILSDMRSQYKVMAEQ-NWKDAE---AWFTSR
----------------TEELN-REVAGHTDQ--LQMSLSKVTDLRRTLQ---GLE--LQS
QLSMK---ATLEGTLAETEARVGAQLAQIQSLINGI-EAQLGDVRADSERQ--NQEYQQF
TDNKSRLQQEIA----TYRSLLEGQEYHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

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----------------------------------SYS-SKSR----SGGGG---------
--GG---GG--------------RG-LSSSSSSVRFGS--GGGG-----RFC--------
-----------SAGG-------------------------------------------GF
G--------------------------GG----FGGGFGG---G----------------
----LG-GGSGGGFG--G-----GFG---------------------------GGF--G-
-GEDGGLLSGNEKVTMQNLNDRLASYLEKVRALEEANADLE---QKIHDWYQKQSPSS--
P--T-RDYSHYYKTIEDLRSQIITTTVENN------------KIVLAIDNTRM-TVDDFR
M-KY-EMELNLRQSVEADVNGLRHVLEELTLSRSDLEMQLQSLQEELEALKKNHEE----
-EMKQMTGQR-SGEVSVEMNAAPSIDLTKALNDMRQEYEMLNAK-NLKEIE---DQYEAQ
----------------MNKMH-QQVTSHSQE--IQTTSSQVTELRRTLQ---GLEIELQS
QLSTK---AALEQSLEETKGRYCVQLAHIQEQIGAL-EAQLSEIRGETECQ--SQEYNVL
LDIKARLEQEIA----TYRSLLEGGQQDIGNASG--------------------------
----------------------------GS-GRGSGSGVLVG--------------GG--
--------------------G-SGG---IRGGSF---G--GGSGT---------------
-----------------------------------------------------------V
-GG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------G----------------
-----------------SG-GG----------------------------SSS--S-FGG
GKSS-Q------------------------------------------------------
---------------------------A--------------------------------
------Q--GSV------------------------------------------------
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--------------------------------------------------

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-------------------LHCFPLTLQ--------LPTNKR-NISPNAM-----SLRFS
GGSRHICLRPG--TGSAGPSNG---G-TRFAGSNACGS-SVAGSGF-S--LGGGLG----
----SVPGGSHAGGA----LGNAVCVGFAASEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANTELERKIKGWY-KYGP-GSCRGLDHD---YS-RYH-TIEDLKNRVISSTTANANV
ILQIDNARLDVCFSICIKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHDA----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSATLQQQISDDAGAATTARNELTEMRRSLQ
TLEIQLQSLLAT----KHSLECSLAETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEHEQLLDIKVHLEKEIETYCRLLDGDGS----SCSKSKVFGSGSSGNPSK-DLSKTTLV
KTVVEEIDQRGKVLSSRVHSIEEK-SKVTSGKA--EQRAPFW--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYT--SKQYSS---SRS----GGG----
-------------------GGGGSAHRISSSKGS-------------LGGGFS-----S-
-GGFSS-S---SF--SRGSSGGGCFGGSSG-GYGG---------------------LG--
-G-------GFGGGSF---GG---GYGGG---SFGGGYG-------------GGSFG---
-GGSFGGGSF------GG----GGYGG-------GGY--------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--G
RGEP-RDYSKYYGPIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKSDLEMQIESLSEELQYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKTEITELRRTIQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSYSSSHGG-GRGG---------------G-----
---------------SYGGSHGGS---SGGGHGGSSGGGHGG-G-SYG------G-HGGS
SGGGHGG--------------SSGGGHGGSSGGGHGGGYGGSSSSGGSHGG---------
----SHGGSHGGGHG--GSSG----------------------GGQSGSGGFKSSSS-GS
TGE---S-SKGPRY----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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----------------------MTSY-RS-------------------------------
-----------------------------------S-------------------SASYY
SSSSGK--GGFGGSSY-----GGSSL---AGSGFGG------------------------
-----------------------GFGSGAGSS----FSSSGGNF----------AM-AAA
ASSSLSNFGGNEKHAMQNLNDRLASYLEKVRALEASNADLE---GKIRTWHEKQT-GTGL
GAGS-KDYSKYFEIISELRGKIHGATVDNA------------TVTLQIDNARL-AADDFR
L-KF-ENELALRQSVEADIAGLRRVLDELTLARGDLEMQIESLTEELAYLKKNHEE----
-EMMHAKSQS-AGKVSVEMDAAPGVDLTNILNNMRADYEILAEK-NRRDAE---LWFTQK
----------------SGELK-KEISVGVEQ--VQASKSEITELKRSLQ---SLEIELQS
QLAMK---QSVEGNLNELQGFYSAQLLQIQNTISSL-EEQLLQIRSDMEHQ--NMEYKQL
LDIKTRLEMEIE----TYRRLLDGELGQMTTVS---------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------KASSLE-SS
S----ESSSTTTTR-------T-----------------RTVK-----------------
---------------TIVEEVVDGKVVSSTVS----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------MFCSAQKGSCS-------SRVSS------------SGA-V
---------------GSRGCTGGSSS-GGGSSCGLGGGS----AWGFQGSS-N-----S-
----------------------WSLSGGSKGS-----------------------MGGGF
GSCSVR--GGFGAASS-----------------YGGGS----------------GFGGGS
G--------FGGGSGFGG---GSGFGGGSSGG----FSSYGG--S-----VGCGLG-G-V
SGYDGGLLSGSEKQTMQDLNDRLANYLDKVRALEEANTDLE---CKIKDWYGKHGSV--K
GGSG-RDYSQYYSIIEDLKKQILSATCENA------------RMTLQIDNARL-AADDFR
M-KY-EHELCLRECLEADINGLRKVLDEMTMTRCDLEMQIEGLTEELVFLRKNHEE----
-EMKCMQGSS-GGDVTVEMNAAPGVDLTKLLNDMRAQYEAMAEQ-NRQEAE---RQFNER
----------------SASLQ-AQISSDAGE--ANCARSEVMELKRTVQ---TLEIELQS
QLALK---CSLEGTLADTEAGYVAQLSGIQAQISSL-EEQLSQIRAETQCQ--SAEYECL
LNIKIRLEQEIE----TYRRLLNGDGGGC-------DYRNLVSKN---------------
-----------------------------------------------------------V
V-----------------------------------------------------------
---------------------------------------------------LSD--S-GS
C----AGQGKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGRVVSSQVSNI----SEVKIK----------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
----------------------MSV-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
--------GGGFGGGFGG-----GFG--------------------------------DF
GGGSGGLLSGNEKITMQNLNDRLASYLDKVRALEEANAELE---VKIRDWYQKQAPTS--
---PERDYSPYFKTIEELRAKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTMSKADLEMQIESLNEELAYMKKNHEE----
-EMKEFSKQV-VGKVEVEMDATPGIDLTRVLAEMREQYEALAER-NRRDAE---EWFHSK
----------------SAELN-KEVTTNAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYALQLQQIQGLISSI-ETQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFPSTGGKKTAPCGSARRT----------
-------S------D-Q-GGTS----------------VN-------S-----STRRPS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------------LDKVKALEESNYELE---QKIKEWYEKNGNA--N
QREP-RDYSRYYDQIKDLKNQILNLTNDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEATLRQSVEADINGLRRVLDDLTLSKTDLEMQLESLNEELAFLKKNHEE----
-EMKDLQNVS-TGDVNVEINAAPAVDLTEYLNRMRTEYEAMAEQ-NRKDAE---AWFNEM
----------------SKELT-TEINTNVEQ--VSSHKSEITELKRSLQ---ALEIELQS
QLALK---QSLEATLADTEGRYCVQLSQIQGQITAL-EEQLQQIRAETECQ--NSEYQVL
LDIKIRLENEIQ----TYRSLLEGGSTSGSSDHEV-------------------------
------------NSSGYG----------GSTSGGGYGRRSSGVQ-GSNSS----------
--------------------------------------VGNGVSSG--------------
--------------------GSG----------EFKSS-----GSRGGSVGGQGEST-VS
GGESPLKSSSGTRF----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-GSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------TGGSYRAP-----
---------------SAYG---------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSSSSSFGGALGGGFGG--------------GYGGGLGGGL
GG----GFGGGFG----G-----GLGGG------------------------------F-
GG-GDGLLVGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---M-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDLISNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------AS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGGG
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSS-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLGGF
GGGSFG--GGYGSSSF---GG---------------------------------GYGGSF
GGGSFGGGSFG------G----GSFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSYGGG-------------------
----------------YGGG----------SSGGGYGGGSSGGG-Y-------GGGHGGS
SGGGYGGG---SSGGGSSGGGYGGGSSSGGYGGGSSGGGHGGSSGGG-------------
-------GSSGGGF------------------------GGGSSGGGSSGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MS---------
-----------------------------LSVRTSGLSRRSSS---Q-N----GAAGR--
---------------PWGASAS--SA-ASC-----YGGL----ASGFGV---G-----C-
GGLISA-A---SM--FGSG---SGFSGSST------------------------------
-------------ASF---AGLGAACGGPLGGGLGGM-----------------------
-------------------------------GM--GI---GGSSG----G--GSL--CIL
SDNDGGLLSGSEKETMQNLNDRLASYLGKVRALEEANAELE---HKIREWYETRRT--GD
SGPQ-SDYSKYYPLIEELKNKIISASVGNA------------QIILQIDNARL-AAEDFR
M-KY-ENELALHQTVEADINGLRRVLDELTLARADLEAQTENLTEELAYMKKNHEE----
-EMQSFQTGG-PGEVNVEMDAAPGVDLTKVLNEMRAQYEVMADQ-NRKDAE---AWFLEK
----------------SGELR-KEISSNTEQ--LQSSKSEITDLRRMVQ---NLEIELQS
QLAMK---KSLENSLAETEGGYCCQLSQVQQLIGSL-EEQLQQLRADAERQ--NADHQRL
LGVKARLEMEIE----TYRRLLDGDGQGTGFDESL---SLAVSK----------S-----
---------------------------------------QTPSV-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPSK-------T-----------------RKIK-----------------
---------------TVVQEIVNGEVVSSQVQELEEAM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYGG---------------LSV-STSRYSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGGLGSGFGG--------------GYGGGLGAGF
GGGF-G-------GGLGA-----GFGGG--------------------------------
----DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---V-KDYSPYFKTIEDLRNKIITATIENA------------QPVLQIDNARL-AADDFR
T-KY-EHELTLRQSVEADINGLRRVLDELTLSRTDLEMQIESLKEELAYLKKNHEE----
-EMLALRGQT-GGDVSVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSGRSEVTELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDLIGNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAQHSLSQQ-ASGHS-Y-SSHNV--FSSSS-----
----------SSSSHQTRPIL---KE---------------------QGSASFNQVQSS-
------KH----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQYSS---SRS----GHGG---
--------------------GGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSAGGCLGGSSI-VYGGG-------------------LGGGF
GG-------GY-------------------GSNFGGSYG-------------GGSFGGGY
GGGSFGGGSFGGG---------------SFG---------------------GGLG-GGF
GG-DGGLISGNEKITMQNLNDRLASYLDKVRALEESNYELE---VKIKEWYEKHGNS--S
QREP-RDYSKYYQTIEDLKNQILNLTTDNA------------NILIQVDNARL-AADDFR
M-KY-ENEVTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLTEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEK-NRRDAE---AWFNEK
----------------SKELT-TEINSNLEQ--VSSHKSEITELRRTIQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGRMGESGKRGGKVHKKA------------------
----------------YATSLSVPTNLTQNTFCPGYKSPSP-------------------
--------------------------GGGSSGGGRSGGYGGSS-----------------
------------GGGG-GXSSGG----------GHGSSSGGGYGGGTSSGGHKSTTS-GS
VGE---SSSKGPRS----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-------------------MSYSASFKQSTK-SGNQGYGG---SQAG-GAYFS-------
--------TSTAGV---------GFG--GAAG------------------YGGGFA--FD
GSA---IGIGNEKEAMQDLNGRLASYLDKVHELEAKNAELE---RKIKEWLDKHGPAP--
AEAP-KDYSKYYKEIEDLKVKIITASKDNA------------VILLQCDNARL-AADDFK
Q-KY-ESEHVLSQAVEADINGLHKVMDDLNMSKTDLQSQLDGLTEELTYLKKNHDE----
-EVKAIKAPV-AGTVSVEMHAAPGSDLTKLLNDMRAQYEDLAQR-NRKEAE---DNFNKL
----------------SADLK-KQIDQGQTV--VVESSTEVTNLKRALQ---SLEIELQS
LLAQK---KSLEMQLAETEGRFCTKLSHIQENIASI-EQHLEQLRAESECQ--KDEYDQL
LDLKTKLEAEIK----TYQSLLDKLGAIKVSQGEGQ-----------------TR-GGQT
RGQD--QMQSQTRGSG--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
---------------------------MALSVSGSALSRRLSA---Q-S----GMAGR--
---------------AQGLSASSLAG-G-------LGGS------GFGLGA-G-----C-
AGGVSA-A---SM--FGSS---SGFGGGSG------------------------------
-------------------WGLGTGHGGLLG-----------------------------
---------------------------SCFGGLGMAF---GGGPG----G--GSA--GIL
CSSDGGLVSGSEKATMQNLNDRLACYLDKVHALEDANTELE---QKIRDWYERRAT--GD
PASR-SDYSKYYPLIEDLRNKIIAASIGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALRLSVEADISGLRRVLDELTLARADMEMQIEGLQEELAYLKKNHEE----
-ELQSFRADG-PGEVSVEMDAAPGVDLTRLLNAMRAQYEAVAEQ-NRKDAE---AWFLEK
----------------SGELR-KEISTNTEQ--LQSGRSEVTDLRRALQ---SLEIELQS
QLAVK---KSLEESLAETERDYCGQLSQVQQLVGHL-EAQLQQVRADAERQ--GGEHQRL
LDAKARLELEID----TYRRLLDGEAAGDGLIET---LPGTDSKSR--------------
----------------------------------------TPST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPSK-------T-----------------RRIK-----------------
---------------TIVQEEINGQVVSSQVQEVEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MSYSSV---------------------KGGGSG
KG--------------------GYS-IESGFNSIRCQLCAARGC-NWCCTNCP----SV-
--------------SNVFAGQGGGL-----------------------------------
----------------GGG--FGRGFGGG----SGGGFG----ARY--GGGFGGGSGSGF
GAGYGGGFGGGSGG---------GFG--GGAK------------------VAYEVT--GT
GGQYGSSVFGNKKETMQNLNDRLANYLDKVNALEAANAELE---RKIKEWYDKQP---TT
SDGG-KDYNKYYSLINELNQKILNAALDNA------------ELALHCENAKL-AAEDFR
L-KY-ESEWTLSQAVVSDINGLRKLMDDLTLSKSSLESQIESLSEELAYLNKTHDE----
-EIKGTQNTK-LSQVSVEMKAQPGTDLTKILNDMRAQHEALAQK-NRREAE---DRYNKM
----------------SAELR-QQISAGVGQ--VQTSKTETSELKKTLQ---ALEIELQA
QIAKK---QSLELMLAETEGSYCMKLSRIQVTISSI-EEHLAQLKGDSECQ--RSKYEQL
LGIKIRLEQEIE----MYRKLLEGGGSNQTS-DVGQ-----------------RR-GGG-
--SG--TSDTTVRTITVKKIVE----------------NVVNG--KVVSKEEVI--ER--
----------------------------L-------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQISRSEVTDLRRTLQ---GLEIELQS
QLSMK---AALEDTLAETEARFGAQLAHIQALISGV-EAQLGDVRADSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGGS-
------------------------S-RMSSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF------SSSS-------------------------SFGGALGSGF
GGGYGGGLVPGFGGGFGA-----GFGGI---------------------------D----
----GGLLSGNEKITMQNLNDRLVSYLDKVRALKANA--DL---VKIRDWYQRQRLSE--
---V-KDYSLYFKTIELM--TIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQLAEK-NRKDAE---AWFLSK
----------------TEELN-REVASHSEQ--VQTSRSEVTELRRVLQ---GLEIELQS
QLSMK---ASLEGSLEETKGRYCMQLSQIQGLISSX-XXXXXXXXXXXXXX--XXXXXXX
XXXXXXXXXX-X----XXXXXXXXXXXXXFSQNTSGQA--YSSR--EV--F---------
------SS--SSSGHQTRPI----LK------------E--QG--SSSFSQSQTSK----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RMSSIL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-SSSRYSSGGG-YGLG------
--------GGYGGGF----SSG-SSFGGGLGSGFGG--------------GYGGGLGGGL
----------------GG-----GLGGG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADTNGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSMRGQV-GGDVNVEMDAAPGVDLSR-LNEMRDQYEKIAEK-NRKDAE---DWS-SK
----------------TEELN-REVATNSEL--VQSSKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELISGV-EEQLAQLRCDMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VV------------DVHDG--KVV------S-----
---------SHEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MTSYYRQ----SSASS----------SFGGL--
-G-------------------------GGTVR-------FGAGG-AYRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSSSGG--------
------------------------------------------------------------
-----------YGGGYAG-----ALV----------------------------------
--GSDRLLAGNEKVTMQNLNDRLASYLDKVRALEAANGDLE---VKIRDWYQKQGP-G--
---PARDYSHYYKTIEELRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRKVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EISALRGQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSQ
----------------TEELN-REVAGHTEQ--LQISKTEVTDLRR--------------
-LSMK---AALEGTLAETEARFGAHLAQIQALISSI-EAQLSDVRADTERQ--NLEYQQL
MDIKTRLEQEIA----TYRSLLEGQDAYY-NNLPTTKT---A------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTTFLQ-TS-S---S----------AFGGG--
ST------------------------RGGSLR-------AGG-G-SFGGGSLYA------
---------------G-GG--------------GRSILASSVRFVSSGSGGGSG------
------------GG------M-SYGFGGGAGSGFG-------------------------
-GGFRGSLGGGFGGGFGG-----GIG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDV-RALEEAA--DL---VKIRDWHQ-QSPAS--
---PXXXXXXXXXXXXXXXXXILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSRADLEMQIESLNEELAYLKKNHEE----
-EMREFSSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVAS-TEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGLISGL-ETQLSELRCEMEAQ--NQEYKIL
LDIKTRLEQEIA----TYRSLLEGQDARM-AGIGTREASL---GGGSS------------
--------------GKLHINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRLS
SGSRRSYARPSTGS--L----R---G-ASFGAGNACGV-AGIGSGF-SCAFGGSS-TGGN
T------------------GVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYGSGNAGNQIK-DSVKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLW-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------M-SCGFGGGAGSGFGG-------------G-FGGGSGSGF
GGGFGGGLGGGFGGGYGG-----GFG--------------------------------DY
GGGDGGLLSGNEKITMQNLNDRLASYLDKVHALEEANGDLE---VKIRDWYQKQSPSS--
---PERDYSPYFKTIEELRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQGVEADINGLRRVLDELTLAKADLEMQIEGLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGLISSL-EAQLSELRSEMECQ--NQEYKTL
LDIKTRLEQEIA----TYRSLLEGQDARM-AGIGTREASL---GGGGG------------
---------------KVRINVE----------------ETVDG--KV----------VS-
------S--RKRE---------------V-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MSCL-------SGVSS---F-------R--A--
---------------------------GGSRMSTGGSSS----AWGFQGGA-G-----S-
----------------------CGLSGGFSGGFGGG-------------------TGGGF
GSCSIE--GRWGAGSG-----SGAGFGGGSG-----------------------------
---------FG------G---ASGFSSGASGG----FCSYGGG-------TGGGFG-G--
GSGDAGLLPGNEKQTMQNLNDRLASYLGKVRALEEANTDLE---NKIKEWYDKFGPGSRD
GGTR-RDYSHYYSILEDLRKQITAATTENA------------RTMLQTDNARL-AADDFR
L-KY-EHELSLRQGVEADINGLRRVLDELTLSKTDLEMQIEGLTKELAYLKRNHEE----
-EMKSVQGSS-GGNVTVQVNAAPGVDLTKLLNDVRAQYEQLAEQ-NRREVE---ERYNEQ
----------------SASFQ-AQISTNAGA--ASSAKTEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADAEVGYVAQLSGIQMKIGSL-EEQICQIRRETECQ--NREYEVL
LDIKTRLEREIE----TYRRLLNGERGGSG-FERSED-----------------------
-----------------------------------------------------------L
V-----------------------------------------------------------
---------------------------------------------------TGNSR----
S----ESQGRDPNK-------T-----------------RVTK-----------------
---------------TIIEEVVDGRVVSSQVSSI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTTFLQ-TS-S---S----------TFGGG--
S-------------------------RGGCLR-------GGG-S-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------M-SSGFGGGA------------------------------
----GGGFGGGYGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEDANADLE---VKIRDWYQKQSPDS--
---PARDYSHYFKAIEELRDKILAATIDNS------------RVILEIDN-RL-AADDFR
L-KY-ENELALRQSVEADINDLRRVLDELTLAKADLEMQIENLNEELAYLRENHEE----
-EMKEFGSQV-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGLVSSL-ETQLGELRSEMEAQ--NQEYKLL
LDIKTRLEQE-T----TYRNLLEGQDARM-AGIGTREASL---GGGGG------------
---------------KLHINVE----------------ESVDG--KV----------VS-
------S--PQER---------------DL------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSSSGGGYG------
------------GG------L-SCGFGGGAA-----------------------------
--------GGGFGGGLGG-----GYG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANTELE---VKIHDWYQKQSPAS--
---PERDYSHYFKTMEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRHSVDADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQL-AGQVNVEMDAAPGLDLTRMLAEMREQYEAIAEK-NRKDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSMK---AGLENSLAEIECRYATQLQQIQGLISGL-ESQLSELRCEMETQ--SQEYNML
LDIKTRLEQEIA----TYRSLLEGQDAKG-GGWERQGGGT---G----------------
-------GGSSSSSSSFRVHVV----------------ESSDG--KL----------VS-
------S--SKRD---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSL-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSVGGYG------
------------GG------I-SCGFGGGAGSAFGGGYG---------------------
-----GGLGGGFGGGFAG-----GFG--------------------------------DF
CAGDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANTDLE---VKIRDWHLKQSPSS--
---PERDYSAYYKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHTK
----------------SAELT-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENSVAETECRYALQLQQIQGLISSI-EAQLSQLRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-IGFPSAGNVSPRSTPVTSTA----------
-------S------AS-----V----------------TT-------T-----SGRRTS-
-------D-VRRP-----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSVRSSS-SKRYSY---AIQ----GGGG-GG
-------------------GGGGSSFRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSS-GGCLGGSSS-GYGI---------------------SGGF
GGSSFG--GGYGSSSF---GG---GYGGG---SF----G-------------GGSFS---
-GGSFGGGGFGGG--FGG----S-----------------------------FGGG-GGF
GG-DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--R
QGEP-RDYSKYYKTIDDLKSQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKTEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NSEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGY-----------------------
---------------------------GGGSSGGGYGGGSSG-G-GYGGGSS--GGG---
YGG--------------------GSSSSGGGYGG-GGSYGGGSSG------------GGG
SYGGGSSGGGGGSS-----------------------------GGGSSSGGHKSSSS-GS
VGD---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTTFLQSSS-STYGG----------GFGGG--
SL------------------------RGASLL-------AGG---GYGGGSLYR------
---------------GG------------------QISASSAKFVSSGSVGGYG------
------------GG------M-SYGFGGGTSGGF--------------------------
--------SAGYGGAFGG-----GF---------------------------------DL
GGSDGGHLSGNEKVTMQNLNDRLASYLDKVRALEEANAGLE---VKIRDWYQKQGPTS--
---PERDYSPYFKTIKELQDKIMEAKADNS------------GIVLEIDNTQL-AIEDFR
N-KY-ENELHLRQNVESDIRDLHKVMEEMNLLKTDLEMKIEDLKEQLDLLKKNHEE----
-EMKEYTNQL-VGQVNVEMDAAPGVDLTRALSEMREQYEGIAEK-NRQDAE---AWFFSK
----------------TEELS-KEVASNTEM--IQSSKTEITDLRRTLQ---GLEIELQS
QLSVK---AGLESSLAETENRYATQLQQIQGIISNI-EVQLSELRNEMECQ--NQQYNML
LDIKTRLEQEIA----TYHSLLEGQDSKM-VDLRTREGSLGGIDG---------------
----------SSSSSKVQITTE----------------ESVDG--KV----------IS-
------S--QKRE---------------V-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MATAFLQ-TS-S---S----------TFGGG--
ST------------------------RGASLR-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SR-LSVASARFVSSGAGGGYG------
------------GG------M-SCGFGG--------------------------------
--GFGGGIGGGFGGGLGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEQANADLE---VKIRDWHQKQSPAS--
---PERDYSPYFKTIEEIRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLARTDLEMQIENLNEELAYMRKEHEE----
-ALKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDAE---AWFFSQ
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAEIECRYALQLQQIQGLISSI-ETQLSELRSEMECQ--NQEYNML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGVGVREASL---GGGGGGS----------
-------SG----SSNFRVHVE----------------ETVDG--KV----------VS-
------S--RKRD---------------I-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYG---------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SGS-SSYG----GGFGG--------------GYGGGLGAGF
G----------------G-----GLGAG------------------------------F-
GGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPTE--
---I-KDYSPYFRTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEMTELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQIRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDTHLS-SQH-TSGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QSSSNFSQGQGS-
------K-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSRS-------TRVSS---S-------RAGGSS
---------------SARVSAAGSSF-SGGSRCGLGGSS----ARGFRGGT-G-----G-
----------------------CGLSGGSSSAFRGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSS---GG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEELRNQNIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYMAQLSEIQTQVSAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKQYSS---SRS----GGG----
-------------------GGGGSSHRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGSSSG-GYGG---------------------LG--
-G-------GLGGGNF---GG---GFGSS---SFGGGYG-------------GGMVG---
-GGNFGIVGSGGG-GFGG----GGYGGGYGGGYGGGY--------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--R
QQKP-RDYSKYYQIIDDLKNKILNLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHDE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---SLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQIATL-EEQLQQIRAETECQ--NTEYQQL
LDIKTRLENEIQ----TYRSLLEGEGSSGGGSYGGGRGGG-SSG----------G-----
---------------GYSGS-----------SGGGYGGSSGG-G-G--------------
-----------------GGGSSSGGGSSGG-GGSSG---GGGSSGGG-----------GP
YG-GGNFGGGGGPHGG-GNFG----------------------GGGSYGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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--------------------------MTSCSRQFTSS--SSKG--------SCGFG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STCGG---------------LSF-SSSRLSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GYGAGFGAGY
-----G-------AGFGG-----GFGAG------------------------------F-
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANADLE---GKIRDWYQRQRPTE--
---T-KDYSPYFRTIEDLRNKIIAATIENA------------QPVLQIDNARL-AADDFR
T-KY-EHELALRQSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLESSLEETKGRYCMQLAQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-TSGQS-Y-SSRDV--FTSSSSSS--
----------SSAGRQTRPIL---KE---------------------QGSSSFSQGQSA-
------KH----------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQFSSS-GSMKG--------SCGIG----
----G-----------------GSS-RMSSVL---------------GGGSCRAS-----
---------------NAFGG-----------------M-SSSRYSSGGA-CGLG------
--------GGYGGGF----SSS--SYGGGLGSGFGG--------------GLGGGFGGGY
GG------------GFGG-----GFGAS------------------------------I-
GGGDGGLLSGNEKFTMQNLNDRLASYLDKVRALEDANADLE---VKIRDWYQRQRPSE--
---V-KDYSHYFKTIEDLRNKIITATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMLALRGQT-GGDINVEMNAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TDELN-KEVASNSQM--VQSNRSEVTELRRVLQ---GLEIELQS
QLSMK-KKASLEGSLEENKGRYCMQVSQIQGMIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSSSQHTSSSSQSYS-SRDA--------VS--
----------SPSGRQTRPLL---KE------------Q---------GSSSFSQGQSS-
------KH----------------------------------------------------
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--------------------------------------------------

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---------------------------MSCS-------SRVSS---S-------RAGGSS
---------------SARVSAGGSSF-SSGSRCGLGGSS----AQGFRGGA-S-----S-
----------------------CSLSGGSSGAFGGS-------------------FGGGF
DSCSVG--GGLGGASG-----SGTGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSRFSSGASGG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEDLRNQIIAATVENA------------GIVLHIDNARL-AADDFR
L-KY-ENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLKKNHEE----
-EMKNMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ATSAKNEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYMAQLSEIQTQISAL-EEEICQIRGETKCQ--NAEYEQL
LDIKTRLEVEIE----TYRRLLDGEGGGS-------SFAEFGGRNS--------G-----
------------S-INM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQGRDS---SK----T-----------------RVTK-----------------
---------------TIVEELVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------MQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQSPAS--
---PERDYSPYFKTIEELRDKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFHSK
----------------SAELN-KEVSTSTAL--IQTSKTEITELRRTLQ---SLEIELQS
QLSMK---AGLESTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKTL
LDIKTRLEQEIA----TYRSLLEGQDAK--------------------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRNISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSAFGG-------------G-FG-------
-GGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTTEELRDKITATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGGS------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-----------------------------GNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIISATTSNANV
ILQNDNARLTA-DDFKLKYENELTLHQSVEADVNSLRRVLDELTLCRTDLEIQVETLGEE
LAYLKK--NHEE----------------------XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTEMEGQK
LEYDQLLDIKVHLEKEIETYCHLIDGEDG----SCVKSKGYGGPGN--QIK-DSSKTTMV
KTIVEEIDPRGKVLSARVHTLEEKSTKVNNVKS--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRLSS---S-------RAGGSS
---------------SARVSAGGSSF-SSGSRCALGGSL----ARGFQGGA-G-----S-
----------------------CGLSGGSSGAFGGS-------------------FEGGF
GSCSVG--GGLGGPSG-----SGACFGGGSS--FGRVS----------------G-----
---------FGRGSGFCG---SSGFSGGAGGG----FCSYGGG-------M----G-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKFGRGSGD
SGSG-RDYSKYYPTIEDLRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQSVEADINGLRKVLDDLTMTRSDLEIQIESLTEELAYLKKNHEE----
-EMKIMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTEAGA--ASSAKNEITELRRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSKIQMQISAL-EEQICQIRGETECQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAGFDGRNS--------G-----
------------S-TNI----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SGQERDS---SK----T-----------------RITK-----------------
---------------TIVEELVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPSNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGAATSARSQLTELRRTLQ
TLEIQLQSLMAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------TGGSCRAP-----
---------------SGYG---------------GLSV-SSSRYSSGGA-CGLG------
--------GGYGGGF----SSSSGGFG--------------------------GGFGGGF
GG----GFGGGFG----G-----GLGSG------------------------------F-
GG-GDGLLVGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---M-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYMKKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELISNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VV------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
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-----------------------------MSVRYSS-SKQHSS---SRS----GG-----
--------------------GGGSSLRISSSKSS-------------HSGGFS-----S-
-GGFSS-G---SF--SRGSSSRGCFGGSSG-GYGG-------------------------
---------GLGGGSF---GG---GYGSSFGGGYGGSFG-------------SCGLG---
-GGSFGGGGFGGG-GFGG----GGFGG-------GSY--------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLANYLDKVRALEESNYELE---GKIKEWYEKHGNS--G
-REP-RDYSKYYQTIEDLKNKILNLTTDNA------------NTLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAFLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTQLLNNMRNQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---GLEIELQS
QLALK---QSLESSLAETEGRYCAQLSQIQAQISSL-EEQLQQIRAETECQ--NVEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGSHGGGRGSS-GGGY----GGSSGG-----
---------------GYGGGHGGG---HGSSSGGGHGG-SSG-G-GYG------GGHGGS
----------------------------------SGGGYGGGHGGS--SGGG----HGGG
SS-GGHGGGSSGGY-----------------------------GGGSSSGGHKSSSS-GS
TGE---S-SKGPRY----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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----------------------MTSY-RS-------------------------------
-----------------------------------S-------------------SASYY
SSSSGK--GGFGGSSY-----GGS--------SFGG------------------------
-----------------------GFGSGAGSG----FSSSGGNF----------AM-AAA
DSSNLSNFGGNEKHAMQNLNDRLASYLDKVKALEASNVTLE---GKIHDWYDSKV-DAGI
GAGS-KDYSKYFEIINELRSKIGAATVGNA------------TVTLQVDNARL-AADDFR
L-KF-ENELALRQSVEADIAGLRRVLDELTLARGDLEMQIESLTEELAYLKKNHEE----
-EMSHAKSQS-AGKVSVEMDAAPGVDLTNILNNMRADYEILAEK-NRRDAE---LWFNQK
----------------SGELK-KEISVGVEQ--VQASKSEITELKRSLQ---SLEIELQS
QLAMK---QSVEGNLSEVQGFYSAQLLQIQNTISSL-EEQLLQIRSDMEHQ--NMEYKQL
LDIKTRLEMEIE----TYRRLLDGELGQMTTVA---------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------KASSVE-SK
T----ESS---TTR-------T-----------------TMVK-----------------
---------------TIVEEVVDGKVVSSRIE----------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGG----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--SVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSHYYRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIENLKEELVYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTH----------------------
------------------------------------------------------------
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--------------------------------------------------

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----------------------MSC-RLQSSS-------ASYGG-GFGSGSCQL------
-----------------GG--------------GRSFSTCSSRFASGGSAGGYG------
------------GG------M-SCGFGGGAGSSFGG------------------------
--------------GFGG-----CFG--------------------------------DF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQRQSPAS--
---PERDYSRYFTTIGELQVKILAATTDNN------------RIILEIDNARL-AADDFR
L-KY-ENELSLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSKQV-VGQVNVEMDATPGVDLTRVLAEMREQYEVMAEK-NRRDAE---AWFQSK
----------------SAELN-KEVASNTEM--IQSSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESSLAETECRYALQLQQIQGLISSI-EEQLAQLRSEMESQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDARL-TVSASPTGSVSYSSTSASSS----------
-------S----VSTSVSGSVS----------------GSASG--SVSVSGSASPRRVS-
------E-VRRF------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRFS
GGSRHVGLQS----GSLRPSSV---G-AGFAGSNAGGS-SAAGSGF-SWALGGPLS----
----SAPGGSHATGT----LGNAAGVGFVGNEGGLLSGNEKVTMQNLNNRLASYLDSVKA
LEEANAELERQIKNWHEKYGP-GSCRGLDQD---YS-QYHLTIEDLKSKIISSTAANANI
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
LTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPSVDLT
ALLNNMRAEYEALAEQNRKDAEA--GFQEKSATLQQQISNDMGAVTSARTELTELKRSLQ
TLEIELQSLSAT----KHSLECSLAETEGNYCSQLAHIQAQISALEEQLHQVRTETEGQK
LEHEQLMDIKAHLEKEIETYCRLIDGDENSCS----N---FESGSSGNSSK-DLSKTTLV
KAVVEEIDQRGKVLSSRIHSIEEKMSKISNGKA--DQRAPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------S--SI-GSG-----YGGS----AFGFGG---N-----S-
GGGFSA-A---SM--FGSS---SGFGSSSGFGGA----------------------C---
-----------GSSFA---GGLGAGYGGAG------------------------------
--------------------------GGGFGGLGIGF---GGSSG----G--GSL--GIL
PGIDGGLISGSEKETMKNLNDRLASYLDKVRALEEANTDLE---TKIREWYETRGSGTGD
PGSQ-NDYSKYYPLIEDLRNKIISANIENA------------QLILQIDNARL-AADDFR
M-KY-ENELALCQNVEADINGLRRVLDELTLARADLETQIETLNEELAYLKKNHEE----
-ELQSCRAGG-PGQVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIE-
---------------KSGELR-KEISSNTEQ--LQSSKSEVTDLRRALQ---NLEIELQS
QLAMK---KSLEDSLAETEGDYCGQLSQVQQLIGSL-EEQLLQVRADAERQ--SADYQRL
LNVKARLELEIE----TYRRLLDGEAQGDSLVESS---YVTASTSQ--------------
----------------------------------------APST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSQDPNK-------A-----------------RKIK-----------------
---------------TIVQEVVNGEVVSSQVKEIEELIVR--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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---------------------------MSCNIKE-TI-TVSSK--GRSSGGSCIIGGGGG
A---R-------------------------------------------------------
-----------------------------ISSYAIGS---GRGFS-GRSYCGGVN-YG--
-------------GGLSVGSLAGGSYGGGN----------------------------CY
GNGLG------------F-----GIGGGVVV---------------------------GG
LGGDCLLSSCDEKVTMQNLNDRLASYLDKVKCLEKENAELE---CRIREWYATQGLSC--
E--P-RDYSCYYKEIEDLQNQIVCATIDNN------------KIILDIDNSRM-AADDFR
V-KY-ETELALRQSVEADINGLRQVLDQLTLCRSDLEAQLESLREELCCLKKNHEE----
-EMNCLRKQS-TGDVSVEVNACPGPDLRQILEDLRCQYETLIAR-NRKEVE---DWYECK
----------------IEEVN-REVITSGQE--VETCNNQVTELRRQLQ---ALEIDLQA
QLSQR---NNLESSLAETECQYNTLLGELQNQITCV-EQQLAEIRAEIECQ--NQEYKTL
LDVKCRLEQEIQ----TYRCLLEGGQQDLIHGG-GIGV----------------------
---------------------G---SGVGG-G-------------VIRTSHT-YTTTTA-
--------------SHCQPQVPPC------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------KTGDI--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATYSFRQTS------S----------AAGGL--
-G-------------------------GRSLR-------LGGVP--FRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSGLGSGPG------
------------GG------YGGA-FSSG------------------------------F
GAGFGGGCG----GGWGS------------------------------------------
---GDGLLSGNEK-TMQNLNDRLASYLDKVRALEEANAELE---TKIREWYLKQGP-G--
---PVRDYSPYYKAIEDLRDQILAATIDNS------------KVVLQIDNARL-AADDFK
T-KF-ETEQALRMSVEADISGLRRVLDELTLARTDLELQIENLKEELAYLKKNHEE----
-EMSALGGQV-AGQVSVEVDSAPGIDLSKILADMRDQYEHMAEK-NRKDAE---AWFHSK
----------------TEELN-REVAINTEQ--LQSSKSEVTDLRRTLQ---GLEIELQS
QLSMK---GALESSLADTEGRYGAQLAQIQEMIGSI-EAQLAELRADLERQ--NNEYKML
MDVKTRLEQEIA----TYRQLLEGQESQL-FGSLSGSPDKGD------------------
---------KLADGK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQTSS-------SVYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSSRFVSSGSMGGYG------
------------GG------M-SCGFGGGAGSGFGGGFGG------GAGG----GYGGGF
GGGFGGAFGGGF----------------------------------------------DL
ASGDGGLLTGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWHLKQGPTS--
---PERDYSPYFKTIEELREKIQAATIDNS------------RVVLEIDNARL-AADDFR
L-KY-ENELTLRQGVEADINGLRRVLDELTLSKTDLEMQIESLTEELAFLKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRTLAEMREQYEALAEK-NRRDAE---AWFQQK
----------------SEELN-KEVTTSTEM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLEATVAETECRYAMQLQQIQGLIGSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSKM-TGFPTSGTGSGISGGTTIS-----------
-----------------------------------------------S-----GNRRTS-
--------ETRKP-----------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SFRLP
SGSRRICSRA----GSVRLPGG---G-PSFGARNVYGG-SGVGSNF-PCTMGGISS----
----GGGLS-NVSRG----LESGVCTGFLGNEQGLFSGNEKMTMQNLNNRLASYLDHVQA
LEDANAELEKKIKDWYEKYGP-GSCRGLDQD---YS-RYMSVIEDLKREIISVTTCNASI
VLQNDNARLTA-EDFRLKYENELTLHQSVEADINGLHQVLEELTLCTTDLEIQLETLSEE
LMCLKD--NHKE----------------------EMKVLQGTAGGNVNVEMNATPGVDLA
VLLNHMRAKYEDLAEQNRKGTEA--WFNEKSAPLQQQIFDDTGAATAARNELMELKRNTQ
SLEIELRSLMAV----KHSHERTLTETEGNYHLQLQQIQDQIGALEEQLQHIRTEMEGQK
LEYEQLLDTKVFLEKEIETYCRLLDGEEGGSKSTCYKSKGCVPVKAGNQVK---------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-S-MKG--------SCGIS----
----G-----------------GSS-RMSSVL---------------AGGSCRAP-----
---------------SAYGG---------------MSV-TSSRFSSGGA-CGMG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GFGGGFG---
-----------------G-----GFGGG------------------------------F-
GGADGSLLSGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPNE--
---I-KDYSSYFKTIEELRSKIIAATMDNA------------QPILQIDNARL-AADDFR
T-KY-EHELTLRQSVEADINGLRRVLDELTLARTDLEMQVEGLREELAYIKKNHEE----
-EMLALRGQT-GGDVSVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---TWFLSK
----------------TEELN-KEVASNSEL--IQSGRSEVSELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGNV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSSQQ---SGQSYSSRE--V--FSSSSS----
-----------SSSRQTRSTL---KE------------Q---------GSVSFNQSQSQ-
------NSR---------------------------------------------------
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---------------------IFDLTTDNA------------NILLQIDNARL-AADDFR
M-KY-ENEVTLHQSVEADINGLRRVLDELTLTKSDLEMQIESLNEELAYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAQN-RD---A---ACFN-E
----------------SRELT-TEINSNIEQ--VSSYKSEITELRRTVQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQSQITAL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGGSGGGGYGYGGGRS-------------GG-----
------------SSGSYGGSSGGGGGSSGGH-----------------------------
----------------------------------GGSSYGGGSSGGHGGSS---------
YGGGS--FGGGGGYGG-GSSSGG----------GQSGSSGGDYGGGSSSGGHKSSSS-GS
IGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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----------------------MSC-RFQSSS-------MSYGG-GFGAGSCQL------
-----------------GG--------------GRNISTCSSRFVTGGSSGGYG------
------------GG------M-SCGFGGGAGGGYGGG-----------------------
---FGGGFGGSCGGGFGG-----GFG--------------------------------DF
GSVDGGLLSGNEKITMQNLNDRLASYLEKVRALEAANADLE---VKIRDWHLKQSPTS--
---PERDYSAYYKTIEELRIKILEATTDNN------------RIVLEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEE----
-EMKEFSNQA-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---AWFQAK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLESTLAETECRYALQLQQIQALISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFNTGGNSTTTSNTSTSP-----------
--------------STSG---------------------R-------P-----DFRKY--
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-------------------------------------------------M-----SFRFS
SGSRRICSQA----GSARLSKG---G-SSFGSGSTSVAPGT-ESSF-ACALGGISS----
----GGNSC-QGGGG----SGSSICTGFLGNEQGLLSGNEKVTMQNLNDRLASYLAHVRT
LEAANAELEGKIEGWYDRYGP-ERFPGLGQD---YS-RYFSAIEDLKNQIISVTACNASI
ILQNDNARLTA-DDFKLKYENELSLHQIMEADTNNLRRVLEELTLCATDLEIQHENLTEE
LTYLQK--NHEE----------------------ETRALQRASGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--CFREKSASLQKQISDDAGAATAARNQLMEQKRSLQ
TLEIELQSLLAM----KQSYEHTLAETEGNYCVQLQQIQDQIGTMEEQLQQIRTETEGQK
LEYEQLLDIKMILEKEIETYCNLLDGEEGTSKAPCYKSKGARPVNSGNQVK-DLTEETFV
KTMVEELDQLGNVLSLRVHSVEEKSSKISNITM--EQRVPAKAP------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGG--
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GLGGF
GGGSFR--GSYGSSSF---GG---------------------------------SYGGSF
GGGSFGGGSFGGG-SFGG----GGFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGEP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDNNIEQ--ISSYKSEITELRRNVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSFGGG-------------------
----------------YGGG-------------------SSGGG-Y-------GGGHGGS
SGGGYGGS---S-GGGYGGGSSGGGSSGGGHGGSSGGGYGGGSSGGG---SS--------
-------GGGGGGYGG-GSSGGG-------------SSSGGGYGGGSSSGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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-----------------------------MSVRYSS-SKHYSS---SRS----GGGG--G
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG---------------------L---
---------GFGGGSF---GG---SYGSS---SFGGGYG-------------G-SFG---
-GGSFGGGSFGGG-SFGG----GGF--------------------------GGGFG-GGF
GGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRG-------------------GG-----
---------------SYGGG--Y----GGGSSGGGYGGGSSG-G-GYG------GGHGGS
SGGGXHG--------GSSGG----------------------------------------
-------------------------------------------GGGSSGGGHKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGSEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-PNYSPYFQTIEDLKNKILTATVDNA------------SIHLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYMKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------REPVTTRQVRTI----VE------------EVQDG--RVISSREQVH-----
----------------------------------QTTH----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-TLGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYYRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGNLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASKQLDS-------PGRLSGA---G-TSFAAGNPCGV-PGIGSGF-SCVFGGSLSAGGY
APG----------------IGSVPYAAFAGTEHILLAGNEKVTMQNLNDRLASYLDKVRA
LEEANAELEQKIKGWYETFGP-GSCRGLDHD---YS-RYLPIIDDLRIQIISATASNANL
VLQNDNARLTA-DDFRLKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLEMLTEE
LTTLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAET--WFSEKSASLQQQISEDTGAAASAKNELTEIRRSAL
ALQIELQSNIAL----KHSLECSLSETEGNYCTQLAQIQAQIGALEEQLHQVRTEMEGQK
LEYQQLLDVKVHLEKEIETYRRLIDGDE---------------GGPGRTGI-SAKRHVIV
KTVVEEIDL-------------QKPSKINK--S--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MS----------SVGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSMHG------
---------------G-SG--------------GRGVSVSSSRFASSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----V------------------------------------
LATSDGLLAGNEKLTMQNLKDRPASYLDKVQALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYTTIQDLRDNILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLEELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGLV-GGQVSVEVDSAPGTDLAKILNDMRSQYQVMAEQ-NRKDAE---AWFTSR
----------------TEESN-RELSGHTEQ--LQIS-----------------------
--SMK---AALDDTLAETEARFGAQLG----LISGV-EAQLGDVR-------------RL
MDIKSRLEQEIA----TYRSPLEGQEDHY-NNLSASKVL---------------------
------------------------------------------------------------
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--------------------------------------------------

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---------------------------MSTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLR-------VGG-G-SFGGGSLCG------
---------------G-GG--------------SRSISASSARFVSSGSGGGYG------
------------GG------M-SCGFGGGAGSGFCG-------------GGFGGGL----
--GGGGGLGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKLTMQNLNDRLASYLDKVRALEEANGDLE---VKIRDWYQRQSPSS--
---PERDYSPYFKTIEELRDKILAATIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIESLKEELAYLKKNHEE----
-EMKEFGGQL-AGQVSVEMDAAPGVDLTRVLAGMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ----LEIELQS
QLSMK---AGLEGSLADTECRYATQLSQIQGLISGL-EAQLSELRSEMECQ--NQEYKTL
LDIKSRLEQEIA----TYRSLLEGQDARM-AGIGTREALL---GGGGS------------
---------------KVRINVE----------------ETVDG--KV----------VS-
------S--HKRE---------------V-------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
SASRRLGSCGG--AGSVRLSTG---G-AGFGAGNTCGG-PGIGSGF-SCTFGGSSSTGGF
GAG----------LS----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIISAATSNASV
ALQNDNARLTA-DDFRLKYENELALHQSVEADINGLRRVLDELTLCRTDLEIQVETLSEE
LAYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEKNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTDTEGQK
LEHEQLLDIKSYLEKEIETYCHLIDGEDGSCSKS----K--GFGGLGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTMEEKPTKV-NNKS--EQRAPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------VD----------------------FPRNTMS---------
-----------------------------LSVGTYGPSQRLSS---Q-S----GTAGR--
---------------VRGVSTS--SA-GSI-----YGGS----IFGFGG---S-----C-
GGGFSA-A---SM--FGSS---SGFGGGSA------------------------------
------------CSFA---GGLGTGYGGSLG-----------------------------
---------------------------GGFGGLGAGF---GVSSG----G--GSI--GIL
SGNDGGLLSRSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGSGIGD
PRSQ-SDYSKYYTLIEDLRNKIISANVGNA------------QLILQIDNARL-AAEDFR
M-KY-ENELALCQSVEADINGLRRVLDELTLARADLEMQIESLNEELAYLKKNHEE----
-ELQSFREGS-PGEVSVEMDATPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFTEK
----------------SGELR-KEITTNKEQ--LQSSKSEVTELRRTLQ---NLEIELQS
QLATK---KSLEDSLAETEGDYCGQLDQVQQLIGCL-EAQLLQVRTDAERQ--NADHQRL
LNVKARLELEIE----TYRRLLDGEVEGDGLDESS---LVRGSKSQ--------------
----------------------------------------TQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDSAK-------S-----------------RKIK-----------------
---------------TIVQEMVNGEVVSSQVQETEEVI----------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-ASFGAGNACSF-PGIGSGF-SCAFGGS-SSGGN
T------------------GGGNSCAGFTLNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANTDLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNKVITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLSRTDLEIQFETLSEE
MTYLKK--NHKE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
ILLNNMRAEYEALAEKNRKDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLNIKSHLEKEIKTYCLLIGGDDGTCKSGGYKSKDCGSANIGNQVK-DSAKAIVI
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RMSSIL---------------AGGSCRAP-----
---------------SAYGG---------------S-L-SSSRYSSGGV-CGMG------
--------GGYGGGF----SS--SSFGGGLGSGFGG--------------GFGGGFG---
-GGL-G-------SGFGG---------G------------------------------L-
GGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQRPAE--
---T-KDYSPYFRTIEDLKNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQSVEADINGLRRVLDELTLARTDLEMQVEGLKEELAYMKKNHEE----
-EMLALRGQT-GGDVSVEMDAAPGRDLSRILNEMRDQYEQMAEK-NRRDAE---AWFQSK
----------------TEELN-KEVASNSQL--VQSSRSEVTELRRVIQ---GLEIELQS
QISMK---TSLEGSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKCRLEQEIA----TYRRLLEGEDAHLSSSQH-SSGQSY--SSHEV--FSSS---S--
----------STTGRQTRPIL---KE---------------------QGSSSFSQSQNS-
------K-----------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR-------------------SCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLA------
------------S-ALGS-NTYSSCYSFGTGS----------------------------
--------------GYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSSYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGVGNACGI-SGIGSSF-SCALGGS-SSGGN
A------------------AGGNPCAGFTVNEAGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSPVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSSSSVNG--DNKSS----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------QY-SSSKQYSS---SRC----GGRS--G
-------------------GGGGSSIKISSSKGS-------------IGGGFV-----P-
-GGFSC-G---SF--SRGSSSGVCFGGSSG-GYGG--------------------IGGGL
GG-----------GSF---GG----------SIFGGGYG-------------GGSFGGGY
GGGGFGGGSFSGG---------------SFG----------------------GFG-GGF
G--EGGLLSGNEKLTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNV--G
QREP-RDYSKYFQIIEELKNQIINLTTDNA------------NILIQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLARADLEMQIESLTEEVAYLKKNHEQ----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRRDAE---AWFNEK
----------------SKELT-IEIDTNIEQ--ISSYQTEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAEIECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGGSSGGVQTGSISY----KVS--SSSSTSV-----
---------------GESSSKGAR---S--------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------ESTMSCS-------SRISP---S-------RAGGSS
---------------SVRVSAGGSSF-SSGSRCGLGGGS----ARGFRGGV-S-----S-
----------------------YGLSGGSGSGFGGS-------------------FGGSF
GSCSVG--GSFGGS--------G------AG--FGGGS----------------G-----
---------FGRSSGFGG---GSGFGSGASGG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYEKFGPGSRD
GASK-RDYSKYYPIIEDLRNQIITATSENA------------GIILQIDNARL-AADDFR
L-KY-ENELYVRQSVEADINGMRRVLDDLTMTRSDLEIQIESLSEELAYLKKNHEE----
-QMKSMQGSS-GGDVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---DQFNKQ
----------------SASLQ-AQISTDAGQ--ASSAKNEITELKRTVQ---ALEIELQS
QLAMK---SSLEGTLAGTEAGYVAQLSGIQTQINSL-EEQVCQIRGETECQ--NAEYEQL
LNIKTGLEMEIE----TYRRLLNGEGGNT-------ECR-----NT--------G-----
------------S-----------------------------SG-W-------------V
S-----------------------------------------------------------
---------------------------------------------------GGDSRS-GS
S----SGQGRDP---SK----T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSHVSNV----SEVKL---------K-------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSRS-------TRVSS---S-------RAGGSS
---------------SARLSAGGSSF-SGGSRCGLGGSS----ARGFRGGA-G-----S-
----------------------CGLSGGSSSAFGGS-------------------FGGGF
GSCSVG--GGFGGASG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSS---GG----FYSYGGG-------M----G-G--
GVGNGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLE---NKIKEWYDKYGPGSGD
GGSG-RDYSKYYSIIEELRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLWQTVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYLKKNHEE----
-EMKSMQGSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEITELKRTLQ---ALEIEFQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQTQISAL-EEEICHIRGETKCQ--NAEYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAEFDGRNS--------G-----
------------S-TNM----G--------------------PR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------SGDSRS-GS
C----SAQGRDS---SK----T-----------------RVTK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVQV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----PLRLS
GAPRLPGLL--------------------------SGN-AALASGL-RCALAGGRA----
----R-------------------AVGSAGSEGGLLPGNEKAAMQSLNDRLAA-------
---ANVGLERKIESWRDRYGPPGSSCGLDGD---YS-DYHLTIEDLRAKIILSTAANANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLQRVLEELALCRTGQELQHESLSEE
VTYLRR--NHEE----------------------EMKTLQCAAGGNVNVEMNAAPSVDLT
VLLSNMRAEYEALAEQNRRDAEA--WFSAKSALLQQQMSQDAGEAMRARTQVTELKRTLQ
TQEIELRSLLAT----KHSLECSLSETEGSYCSQLAQIQAQVGALEEQLHQVRTETEGQK
LEYGQLLDLKVHLEKEIETYCRLIDGDDG----SCSKLKGVGLGSPGSSSK-DLSKTTLV
KTVVEELDQNGKVLSARVHSIEEKTLKLPNSKTGQRQRPPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYTSTSKQYSS---SRS----GGGG---
-------------------GGGGSTHRISSSKGS-------------LGGGFS-----S-
-GGFSS-S---SF--SRRSSGGGCFGGSSS-GYGG--------------------LGGGF
SGGSFG--GVFGG----------------------------------------GSFGGGY
GGGSFGGGSFGGS--------------------GYGS--------------LGGF-----
--GDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--G
RREP-RDYSKYYQTIEELKNQIVSLTTDNA------------NVLLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKSDLEMQIESLTEELQYLKKNHEE----
-EMKDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRKEAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSIKTEITELRRTVQ---SLEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLESEIQ----TYRSLLEGEGG---------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------GGSSGGQGGSGGFKSSSS-GS
TGE---S-SKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----TSAMS----------SFGGT--
-G-------------------------GGSVR-------IGSGG-VFRAPSIHG------
---------------G-SG--------------GRGVSVSSTRFVTS-SSGS--------
------------------------------------------------------------
-----------YGGVRGG-----SFSG----T--------------------------L-
-AVSDGLLSGNEKITMQNLNDRLASYLDKVRALEQANGELE---VKIRDWYQKQGP-G--
---PSRDYNHYFKTIEDLRDKILGATIDNS------------KIVLQIDNARL-AADDFR
T-KF-ETEHALRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEE----
-EITALRSQV-GGQVSVEVDSTPGVDLAKILSEMRSQYEIMAEK-NRKDAE---ATYLAR
----------------IEELN-TQVAVHSEQ--IQISKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARYGVQLSQIQSVISGF-EAQLSDVRADIERQ--NQEYKQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKA---I------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQLTSS-SSTKG--------SCGLGGSG-
------------------------R-----------------------VSSCLGP-----
---------------STYG---------------GLSV-S-SRFSSRGA-CGMG------
--------GGAAGGF------SSNS-------------------------GFGGG----Y
GGGLGGGLAGGFGGVFGG-----GYGGL---------------------------G--GG
FGGGDVLLSGNEKVTMQNLNDRLASYLDKVRALEAANADLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLKSKIVMATMENA------------QSILKTDNARL-AADDFK
N-KY-EHELNLRQTVEADINGLRRVLDELTLARADLEMQIEGLKEELAFLRKNHEE----
-EMLALRGRT-GGDVNVEVDAAPGVDLSRILNEMRDQYEQMAEK-NRREAE---AWFLSK
----------------TEELN-KEVASSSEL--IQSGRSEISELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQEMIGSV-EAQLAQLR---------------
----------------------------CEMEISGGQA--YASR--EV--F---------
------SS--S--SRQPKPI----LK------------E--QS--SASFSHSQSSQN---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGL-----
------------------------G-GGSSR------------------TSCRLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
------------S-ALGG-SSYSSCYSFGSGG----------------------------
--------------GYGS-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQRQAPGP--
---A-RDYSQYHRTIEELQNKILTATVDNA------------NILLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
--------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRSVSACSTRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGFGG------GL------------
GGGFGGGLGGGFGGGFGG-----GFG--------------------------------DY
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANTELE---VKIRDWYQKQSPSS--
---PERDYSPYFKTIEELRDKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLNEELAYLKKNHEE----
-EMKEFSSQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHSK
----------------SAELT-KEVTSSTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLEGTVADTECRYATQLQQIQGLIGSL-EAQLSELRSEMECQ--NQEYKTL
LDIKSRLEQEIA----TYRSLLEGQDARM-AGLTSSGGKETTPGNSSVTV----------
-------T------TT-----S----------------SN-------S-----SGRRTS-
-------GTGRL------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
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-------------------------------------------------M-----SLRLS
SASRRSCPRPTT--GSLRLSGG---G-TSFGAGNACGI-SGIGSNF-SCAFGGS-SSGGN
A------------------AGGNPCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRSISASSSRFVSSGSGGGYG------
------------GG------M-SCGFGGGAGGGFGG-------------G-FG-------
-GGAGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---GKIRDWYQKQAPTS--
---PERDYSHYFKTMEELQDKILAAAIDNS------------RVILEIDNARL-AVDDFR
L-KY-ENELGLRQSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYMKKNHEE----
-EMKEFGSQL-VGQVNVEMDAAPGVDLTRVLAEMREQYEAIAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLISSL-EAQLSELRCEMEAQ--DQEYRML
LDIKTRLEQEIA----TYRSLLEGQDAKM-AGAGIREASL---GGGSGGS----------
-------------SSGVRIKVE----------------ESVDG--KV----------VS-
------S--HKRE---------------V-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD----------------------LSNSTMS---------
-----------------------------LSVRTPGLSRRLSS---Q-S----VIAGR--
---------------PRGMSAS--SV-GSG-----YGGS----AFGFGP---S-----Y-
GGGFSA-A---SM--FGSS---SGFGGGSG------------------------------
------------SSM-----------AGGLGAGYGRA-----------------------
------------------------LGGSGFGGLGMGF---GGSPG----G--GSL--GIL
SGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELE---NKIREWYETRGTGTGD
A-SQ-SDYSKYYPLIEDLRNKIIAANIGNA------------QLLLQIDNARL-AAEDFR
M-KY-ENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEE----
-ELQSFRVGG-PGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQ-NRKDAE---AWFIEK
----------------SGELR-KEISTNTEQ--LQSSKSEVTDLRRAVQ---NLEIELQS
QLAMK---KSLEDSLAEAEGDYCAQLSQVQQLISNL-EAQLLQVRADAERQ--NVDHQRL
LNVKARLELEIE----TYRRLLDGEAQGDGLEES---LFVTDSKSQ--------------
----------------------------------------AQST-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPTK-------T-----------------RKIK-----------------
---------------TVVQEMVNGEVVSSQVQEIEELM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLCLS
SGPRRSCSRPTT--GSVRLSSG---G-SVFGSG--NGV-PGIGSGF-SCAFGSSSTG---
G------------------NSSTSCASFLGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEEKIKGWYEQFGP-GSCRGLDHD---YS-RYLPIIEDLKNQIITSTTSNASA
VLQIDNARLTA-DDFRLKFESELAFHQNVEADVNGLRRVMDELTLCRTDLEIQYETLNEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
LLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISDDVGATTSARSELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLSETEGNYCVQLSQIQAQIGALEEQLQQVRTETEGQK
LEYEQLLHIKVSLEKEIETYCLLIDGDEGACKSGGYKSKDHGSGNLGSQAK-EPGKAIVV
KK-LEEIDQRSKVLTTRLQSLEEKAPSN----------------------

------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNVACVGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGATTSARSQLTEMRRTLQ
TLEIQLQSLMAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSYSTKQ-TV-TLATK--GKSSGGSCVVGGGGA
GKISS-------------------------VSSGRYGSC--GLG-SGGGFSCR-S-----
-----------FSGGAGKISSV---SSGRYGSCGLGS---GRGFS-CRSFSGGAG-----
---------------SFSGGSCGGVFGGGLP-GYSCGGCP---GVGLSGGASHCGYGGGF
GGGFG------------A-----AVSGGFLG---------------------------GG
VCGDGAFVTCDEKLTMQNLNDRLASYLDKVRCLEEENAALE---CKIREWYAQHGHSG--
L--P-KDYSCYHKEIEDLQNQIVCATLDNN------------KIILNIDNSRM-AADDFR
L-KY-ETELALRQSVEADINGLRRVLDELTLCRSDLEAQLECLKEELCCLKKNHEE----
-EIICLRNQS-TGDVSVEVNSSPGPDLKKILDEMRCQYETMIAQ-NCKEVE---DWYECK
----------------IEEVN-REVITSGQE--VESCNNQVSELRRQLQ---CLEIDLQA
HLSQR---DNLEASLAETESRYNAHLCQLQQQITCV-EQQLSDLRAEIESQ--NHEYKVL
LDVKCRLEQEIH----TYRCLLEGGQRDIIVPEGGIGV----------------------
---------------------G---SGA-----GK-CAGGGGV--VIKSSHS-YST--S-
--------------SHCLPHVPPC------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------HPAEK------GHGRKICD------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
----G-----------------G-----SSC------------------ASCWLS-----
---------------GGLGA----------GSCRL-------GSA-----GGLG------
--------SALR------GSTYSSCYRFGSGGG---------------------------
---------------YGS-----SFG----------------------------------
--DVDGLLARGEKATMQHLNDRLASYLDKMRTLEEANTELE---VKIRDWYQRQAPGP--
---A-HDYSHYYRTIEELQ-----------------------------------------
N-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMHIENLKEELAYLKKNHE------EMNALRGQV-GGEINVEMDAAPGVDLSRILNKMREQYEKMAEK-NRKDAE---DWFFSK----------------TEELN-REVATNSEL--VQSGKSEILELQHTMQ---ALEIKLQFQLSVK---ASLEGNLAETENRYCMQLSQIQGLIGSV-KEWLAQLRCEMEQQ--NQEYKILLDVKTRLELEIT----TYHRLLEGEDAHLTQY-----------------------------------KKEPVTTCQVCTI----VE------------EVQDG--KVISSHEQVH---------------------------------------QTTR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEELQ-----------------------------------------N-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMHIENLKEELAYLKKNHE-----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILNKMREQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEILELQHTMQ---ALEIKLQF
QLSVK---ASLEGNLAETENRYCMQLSQIQGLIGSV-KEWLAQLRCEMEQQ--NQEYKIL
LDVKTRLELEIT----TYHRLLEGEDAHLTQY----------------------------
-------KKEPVTTCQVCTI----VE------------EVQDG--KVISSHEQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MTSAYSYRQ----SSATS----------SFGGL--
-G-------------------------GGTLR-------HVTGG-SYRAPSIHG------
---------------G-SG--------------GRGVSVSSARILSS-SS----------
------------------------------------------------------------
-------------GGYGG-----GYGG----S--------------------------L-
-VLSDGLLAGNEKFTMQNLNDRLASYLAKVRALEEANGQLE---VKIRDWYQKQGP-G--
---PSRDYSNYYQIIEDLRDKILAATIDNA------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-ELSVLKGQI-GGQVSVEVDSAPGVDLAKILSDMRSQYEVMAEK-NRKDAE---AWFISQ
----------------TEELN-RTVAGHTEQ--LRVSNSEVTELRRNLQ---GLEIELQS
QLSTK---AALEGTLAETEARYGAQLAQIQALISSI-EAQLSEVRADTERQ--NQEYQLL
MGIKSRLEQEIA----TYRSLLEGHEAHR-TTLIEAL-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLS
SGSRRAYTHPT--TGSLRLSS----GGASFGAGNTCGV-PGIGSSF-SCAFGSSSL----
----GGNAG-----------GINSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
MTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRTLQ
TLEIEHQSLLAT----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXACKSGDYKSKDYGSGNAGSQVK-DPIKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQNN----------------------

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SGSRHICLWSG--AGSVRPSSG---G-LGFAGSNACGS-SVAGSGF-SCALGGGLG----
----NVPGGNHAGGV----LGNAACAGFAGSEGGLLSGNEKVTMQNLNDRLASYLGNVRA
LEEANAELERKIKGWYDKYGP-GSCRGLDHD---YS-RYYQIIEELKNKVISSTIANANV
ILHMDNARLAA-DDFRLKYENELALHQNTEADINGLRRVLDELTLCRTDQELQYESLSEE
LRYLKK--NHEE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGVCKSGGYKSKDYGSGNMGNQVR-DLAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
GGSRHVGIQS----GSLRPPSG---G-AGFAGSSVAGG-SVAGSGF-SWALGGTLG----
----SAPGGSHATGA----LGNVSGVCFIGSEGGLLSGNEKVTMQNLNNRLASYLDNVKA
LEEANSELERKIKTWHEKYGP-GSCRGLDRD---YS-KYHLTIEDLKSKIISSTAANANI
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQISNDLGAATSARTELTELKRSLQ
TLEIELQSLSAT----KHSLECSLAETEGNYCSQLAQIQAQISALEEQLHQVRTETEGQK
LEHEQLLDIKAHLEKEIETYCRLIDGDENSCS----VSKGFESGTSGNSPK-DVSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKMSKMSNGKA--EQRVPF---------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----STRFS
SASRRLGSCGG--PGSVRLSSG---G-AGFGAGNVCGV-PGIGSGF-SCSFGSSSSAGSY
GGG----------LA----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLRTQIISATTSNANV
VLQNDNARLTA-DDFRLKFENELALHQSVDADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRSEYEALAEQNRRDAEA--WFNGKSASLQQQISDDAGATTSARDELTEMKRTLQ
TXXXXXXXXXXX----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDAKIHLEKEIETYCHLIDGENDSCSKS----K--GYGGPGNQIK-DSSKTAIV
KTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKS--EQRVPS---------

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRIS
TGPRRICSWSG--AGSVRIPNG---S-TSFGNNSLCGG-SIVGGGN-L--PGGGYGSCFG
GSSGGSPSGNPVGGS----FGSASCAGFGGNE-GLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANSELEQKIKGWYEKFGP-GSCRGLDHD---YS-RYQLTIEELKNKLISSTTSNANV
VLQIDNARLAA-DDFRLKFENELAFHQSVEADINGLRRVLDELTLCRTDLEIQYETMNEE
LTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSATLQQQISDDAGAATSARSELTEMKRTVQ
TLEIELQSLLAT----KHSLECSLNETEGNYCVQLSQIQAQIGALEEQLQQVRTETEGQK
LEYEQLLDTKIRLEKEIETYCRLIDGDGSSCS----KTKGYGSGVSGNSTK-GIKMHSYF
YCFL----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MFCSAQKGSCS-------SRVSS-----------SSGA-V
---------------GGRGCTGGSSF-GGGSSCGLGGGS----AWGFQGSS-S-----S-
----------------------WSLSGGSKGS-----------------------MGGGF
GSCSVR--GGFGAASS-----------------YGGGS----------------GFGGGS
--------------GFGG---GSGFGGGSSGG----FSSYGG--S-----VGCGLG-G-V
SGYDGGLLSGSEKQTMQDLNDRLANYLDKVRALEEANTDLE---CKIKDWYGKHGSV--K
GGSG-RDYSQYYSVIEDLKKQILSAICENA------------RMTLQIDNARL-AADDFR
M-KY-EHELCLRECLEADINGLRKVLDEMTMTRCDLEMQIEGLTEELVFLRKNHEE----
-EMKCIQGSS-GGDVTVEMNAAPGVDLTKLLNDMRAQYEAMAEQ-NRQEAE---KQFNER
----------------SASLQ-AQISTDAGE--ANCARSEVMELKRTVQ---TLEIELQS
QLALK---CSLEGTLADTEAGYVAQLSGIQAQISSL-EEQLSQIRAETQCQ--SAEYECL
LNIKTRLEQEIE----TYRRLLNGDGGGC-------DYRNLVSRN---------------
-----------------------------------------------------------V
V-----------------------------------------------------------
---------------------------------------------------LSD--S-GS
C----AGQGKDPSK-------T-----------------RVTK-----------------
---------------TIIEEVVDGRVVSSQVSNI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-------------------------------------------------M-----SLRLS
SGSRRSYARPSGGS--L----R---G-TSFGAGNTCGI-GGIGSGF-SCAFGSSS-TGGN
T------------------GVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLENVQA
LQEANADLEQKIKSWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSASYKSKDYGSGNAGNQIK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
GGSRHAGLQS----GSLRPPSG---G-AGFAGSSAAGG-SVAGSGF-SWALGGTLC----
----SAPGGSHATGA----LGNVTCVGFAGSEGGLLSGNEKVTMQNLNNRLASYLDNVKA
LEEANTELERKIKTWHEKYGP-GSCRGLDRD---YS-NYHLTIEDLKSKVISSTAANANI
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSATLQQQISNDLGAATSARTELTELKRSLQ
TLEIELQSLSA-------------------------------------------------
--------------------------------------TGFESGTSGNSSK-DVSKTTLV
KTVVEEIDPRGKVLSSRIHSIEEKMTKISNSKA--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MATKSIRQISTS-GSVKG--------LCMPS----
----G-----------------GFS-RMSSIR--------------VGGA-CRAP-----
---------------SLLGV----------GSSGNMSM-SSSRFS-----MGLG------
--------GSYG-------G----GYTCNLGGGFGS------------------------
--------------SFGM------------------------------------------
---ADNLLGGSEKETMQNLNDRLASYLEKVRALEEANADLE---VKIHDWYKKQGPGP--
---A-RDYSHYFKTIEELRSKILAATIDNA------------NLVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSSRTEITELRRTVQ---NLEIELQS
QLSMK---ASLEGSLAETEARYGAQLAQLQGLISSI-EAQLSELRCDMERQ--NQEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLSTQYSSS-L-------------------VSQ
P-----TREGTVTTRQVRTI----ME------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------GGSVR-------FSGGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-SA----------
------------------------------------------------------------
------------SGGYGG-----GYAG----A--------------------------L-
-AVSDGLLAGNEKFTMQNLNDRLASYLAKVRALEEANGELE---VKIRDWYQKQGP-G--
---PSRDYSQYYQTIDDLRDKILAATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISALRGQV-VARVSVEVDSAPGIDLAKILTDMRNQYEVMAEK-NRKDAE---AWFTSR
----------------TEELD-QQVAVHTEQ--LQISKTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAKLAQIQALISSI-EAQLSEVRADTERQ--NQEYQQL
LGIKSRLEQEIA----TYRSLLEGQDA---------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
---------------------------MALSVRTSGGPRQFSS---R-S----GFGGG--
---------------SLRISSS--------SGGGGFGGS----GLGFGG---G-----S-
GGGFGA-A---SL--LGS--------------------------------------SSGF
-----G--GGFGGGLG---GSYGSGLG----SGFGGGL----------------G-----
-------------SGFGSS-SGAAFGSGFGGGLGTG--------------FGGGF--SPA
GAGDGGILSGSKKETMQNLNDRLAAYLDKVRSLEDANTELE---RKIREWYEKNGPGTGT
PGSG-NDYSKFYPLIEDLRNKIINATIDNA------------RIILQVDNARL-AADDFR
V-KY-ENEVALRQSVEADINGLRRVLDELTMTRADLEMQIESLNEELAYLKKNHEE----
-ELQGIQSSE-LGQVSVEMDAAPGTDLTKLLNDMRGQYEVIADQ-NRKEAE---AWFNEK
----------------SGELK-REISTHTEQ--LQSGKSEITDLKRTLQ---SLEIELQS
QLAMK---KSLEDTLAETEGGYCAQLSQIQMQIGNL-ESQLFQVRADMERQ--NAEYQQL
LDIKTRLEMEIE----TYRRLLDGD---AGQAATFESSSLTGSKSQ--------------
----------------------------------------TQSL-DS------------S
Q-----------------------------------------------------------
------------------------------------------------------------
----------DPTK-------T-----------------RKIK-----------------
---------------TIVEEVVDGKVVASHVKE---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MSLSVLSSGLSQRMSE---Q-S----RVAGQ--
---------------ARGLSTSSPVG-G-------PGAS----AFGFGAGGFC-----C-
AGGFSA-A---SV--FGSS---SGFSGAST------------------------------
------------CSLA---RGLGTGHGGPLG-----------------------------
---------------------------GGFRGLGMAF---GDSPA----G--GSA--GIL
GGNDGGLVPGSEKATMQKLNDRLASYLEKVRALEEANADLG---QKIRDWYERQGSGARD
SSSQ-NSYSKYYPLIEDLRNKVLSASIGNA------------QVILQVDNAKL-AAEDFR
M-KY-ESELALHQMVETDIHGLHRVLDELTLPRADLEMQIEGLNEELAYLKRNHKE----
-ELQSIRAKG-PREISVEIDAVPGVDLTRLLNNMRARFEVLTEQ-NRKDAE---AWFVEK
VSTGHSALTLRLSTLQSGELQ-KEISSNTEQ--LQSSRS---------------------
---EK---KSLEDSLAETEGGYCSQLSQVQQLVGNL-EAQLQQVRTNAKCQ--GAEHQRL
LDATARLELEIE----TYRRLLDGEAAGDGLDESS---SVTVSNSQ--------------
----------------------------------------AQSI-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RTIK-----------------
---------------TIVQEVINGEVVSSQVQEIEEVM----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
-------------------------------------------------M-----SFRLS
GGSRRICSRT----GSGRLSGG---G-TGFVAGNVCVG-SGARSSF-SCTLEGISS----
----GGSFC-NSGGG----LGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHA
LEEANADLEQKIKGWYEKCEP-GSSREHDHD---YS-RYFSVIEDLKRQIISATICNASI
VLQNDNARLTA-DDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEE
LTYLKK--SHEE----------------------EMEVLQYTAGGNVNVEMNATPGVDLT
VLLNNMRAEYEDLAEQNRKDAEA--WFNERSATLQQQISDHEGAATAARNELTELKRNLQ
TLEIELQSLMAV----KHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQK
LEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAK-DSTEETIV
KTVVEELDQIGNLLSLRVHSVEEKSSKISNITV--EQRVPSKAP------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRLP
SGSRRASPRP--TTGSLRLSGA---G-ASFGAGNACSM-PGIGSSF-SCAFGSSS-SGGN
A------------------LGGNPCAGFTMNEGGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLKNQIIASTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVESDVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQVLQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQITEDVGATTSARNELTEMKRNLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIGGDDGACKSGGYKSKDYAAGNMGNQMK-DPIKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RI-SMI---------------GGGSCRAP-----
---------------SAYGG----------SGFGGMSV-TTSRFSSGGA-CGLG------
--------GGYGGAF----SSS-SS--------FGG--------------GYGSG--AGY
GS----GFGGGYGGGFGG-----GYGGG------------------------------F-
GS-MDGLLAGGEKVTMQNLNDRLAAYLDKVRSLEEANTELE---VKIRDWYQKQRPTE--
---R-KDYSPYYRTIEELKNKILTATVENA------------NILLQIDNARL-AADDFR
T-KY-ETEANLRMSVEADINGLRKVMDELTLSKADLEMQIENLKEELAYLRKNHEE----
-EMNSLKGQV-GGDVNVEMDAAPGVDLTRELTEMREEYEALVEK-NRKDAE---AWFFSK
----------------TEELN-REVTSNSEL--VQSGKSEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCLQLSQIQGLISNV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLASQ------------------FSSSSQSP--
-------KDVSSTSRQVYT-K---VL------------DVQDG--KVVSS--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MGIKHSH--------PFP-----------IY
PSTFSP---LSQLLAR-S-LTSLLGTMTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----AGL
GG----GL--------GS-----GFGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSATS----------SFGGM--
-G-------------------------GGSVR-------FGPGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------FGGGYTS-----V------------------------------------
LAGSDGLLAGNEKLTMQNLNDRLASYLDKVRALEEANGDLE---VKIRDWYQKQGP-G--
---PSRDYSPYFKTMEDLRDKILSATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVSVEVDSAPGIDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHTEQ--LQMSKSEVTDLRRTLQ---GLEIELQS
QLSTK---AALEGTLAETEARFGAQLAQIQALIGNI-EAQLGDVRTDSERQ--NQEYQRL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NDLSAPKVL---------------------
------------------------------------------------------------
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-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTANEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHTVEEKATKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-S-SRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGGGLGAGF
GGGL-G-------AGFG---------GG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVLQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQQ-ASGQSYS--SREA--EITPS--H--
----------SSLGNRVRSCL---KN---------------------NSSLLYFSYLIA-
------LHVFSTVSCSCFKMQ---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSLSVRTSGQSRRLSS---Q-S----KMAGR--
---------------PQRMSAA--SL-ANG-----YGGR----TFGCGV---G-----C-
EGGLSAAA---SM--FGTG---SL------------------------------------
-------------------AGPGTGYWGPLG-----------------------------
---------------------------GGFGGLGMGF---GGSGG-------GSA--CIL
SGNDGELPYGSGKETI------LASYLGKVRALEEANAALE---SKIREWCELQRT--GD
SGSQ-SDYSKYNPMIEDLKNKIISASIGNA------------QIILQIDNVRP-AAEDFR
P-KY-ENELALWQLVEANINGLRRVRDELTLTRANLEAQIEDLTKELVYLNKNHE-----
-ELQSFQADG-PSEVNVEVDAAPGMDLTRVLNKMRAQHEAMADQ-NRKDAE---AWFLEK
----------------SGELR-TEINSNTEQ--LQFSKSEVTDLRRTMQ---NLEIEPQS
QLAL----KSLEDSLAETEGGYCCQVSQVQQLIRSL-EEKLQQMRADAERQ--NVS----
----LEMEIETE----TYRHLLDGETQGDGFDDSS---SVTVSKSQ--------------
----------------------------------------APPT-D--------------
------------------------------------------------------------
------------------------------------------------------------
-------SSKDPNK-------T-----------------RKIK-----------------
---------------TIVQEVMNGEVVSSQVQEIEEMI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SGSRHICLRSG--TESLRPSSG---G-TGFAGSNAWGN-SGAERGF-SYALGGGLG----
----SLPGGDHAGGI----PGSGTCAGFAGNEGGLFSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELEREIKSWYEKHGP-GSCRGLDHD---YG-RYHLTIEDLKNKIISSTMANANI
ILQIDNARLAA-DDFRLKYENELALHQNTEADINGLRRVLDELTLCRTDQELQYESLSEE
LTYLKK--NHEECQGIQNKEFHVSRSALRISSPKEMKALQCAAGGNVNVEMNAAPGVDLT
LLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISDDAGAASSAQGELTEMKRTVQ
TLDIELQSLLAT----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDRNSCS----KSKGFESGSPGNSSK-DLSRTTLV
KTVVEEIDQRGKVLSSRVQSIEEKTSKMTNGKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKGS----------FGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-YGLG------
--------GGYGGGF----SS-SSSFGSG----FGG--------------GYG----GGL
GA----GL--------GG-----GLGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SVRFS
STSRRLGSCGG--AGSVRLSSG---G-AGFGAGNTCSV-PGIGSGF-SCAFGGSSSAGGY
GGG----------LG----GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDELKNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCLLIDGEDGSCSKS----K--GYGGPGNQTK-DSSKTTIV
KTVVEEIDPRGKVLSSRVHAVEEKATKV-NNKN--EQRVPS---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSSTS----------SFGGL--
-G-------------------------GGSVR-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGGYGG-----I------------------------------------
LAASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSRDYSHYYKTIQDLRDKILGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-ELSVLRGQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAVHREE--IKTSHTEVSDLRRTLQ---GLEIELQS
QLSMK---AGLEGTLAETEARFGAELAEIQARISGV-EAQLGDMRADSEQR--NQEYQRL
LDVKSRLEQEIA----TYRSLLEGQEDRY-NNLSASKVL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
--------------------------MAVYNYHQ----SSSAS----------SFGGM--
-G-------------------------GGSML-------FGVGG-HFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSSSSSGG--------
------------------------------------------------------------
-----------YGSGYGG-----VLS----------------------------------
--TSDGLLSGNEKITMQNLNDRLASYLDKVRALETANTDLE---VKIRDWYQKQGP-G--
---PARDYSHYYKTIEDLRDQILGATIQNS------------KVVLQIDNARL-AADDFR
T-KF-ETEQALRVSVEADINGLRRVLDELTLARADLEMQIEGLKEELAFLKKNHEE----
-EISVLKAQV-GGQVSVEVDSTPGIDLAKILNDMRSQYELMAEK-NRKDAE---AWFIKQ
----------------TEELK-LEVDVHTEK--LQVSKTEVTDLRRTLQ---SHEIELQS
QLSMK---AALEGTLAETEARFGAHLAQIQAMVSSM-EAQLSEVRSDMERQ--NQEYQLL
LGIKSRLEQEIA----TYRSLLEGQDAHY-KDLATTRV---L------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------AGISS---S-------RA----
---------------------------SGSKQSAVRGSS----AWGFQGRG-S-----S-
----------------------CGF-------------------------------GGGL
RGGSVG--GRWGAGSG-----SGAGFGKGSC-----------------------------
---------FGGGSGFTG---VSGFSVGTGGG----LCSYGGG-------MGGGFG-S--
GMGDGGLLSGNEKLTMQNLNDRLASYLDKVRALEEANTDLE---NKIKQWYDKFGPGSGD
GGSR-RDYSNYCRILEDLRKQIAAAAVENA------------RIILQIDNARL-AADDFR
L-KY-ETELALHQGVEADINGLRRVLDELTMTRSDLEAQIEGLQEELICLRKDHEQ----
-EMKSVLGSC-GGDVTVAVDAAPGTDLTKLLNEMRAQYEQLAEQ-SQQEAE---EHFLEQ
----------------STSLQ-TQISTDAGA--ASSAKKEIAELKRALQ---GLEIEFQS
QLAMK---SSLERTLADTEAGYGAQLSGIQAQIGSL-EEHLCQVRAETKCQ--DREYGLL
LDIKTRLEAEIE----TYRRLLHGEGSGSG-FERSRN-----------------------
-----------------------------------------------------------L
D-----------------------------------------------------------
---------------------------------------------------LSHSR----
P----DHPERDSGK-------T-----------------RVTK-----------------
---------------TIIEEVVDGKVISSQVSSI----SEVKIK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQTSRQSSVTP----------SLGGL--
-G-------------------------GGSVR-------FGAGG-ALRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS-GAGG--------
------------------------------------------------------------
-----------YGGGF---------VG----G--------------------------M-
-AGQDTLLGGDEKVTMQNLNDRLASYLDKVRALEAANGDLE---LKIRDWYQKQGP-G--
---PTRDHSHYYKTIQDLRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EVSALRSQV-GGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTSR
----------------SEELT-REVAGHTEQ--LEVSRTEVTDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISSI-EAQLSDVRADTERQ--NLEYQQL
MGIKSRLEQEIA----TYRSLLEGQDAHY-NNLPGPKA---V------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKGS--------CGIGG---
-GIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSSSSSFGSG----FGG--------------GYG----GGL
GA----GL--------GG-----GFGGG------------------------------F-
AG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MASTTSIRQFSTS-SSVKG--------LCTPG----
----M-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGNMSV-TSSRFS-----AGLG------
--------GGYG-------G----GYACSLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGGEKETMQNLNDRLATYLDRVRALEEANTDLE---VKIRDWYKKQGPGP--
---T-RDYSPYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------ASQ
P-----SREGMVTSRQVRTI----VE------------EVQDG--KVVTSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGGS-
------------------------S-RMSSVL---------------AGGSCRAP-----
---------------STCG---------------GMSV-TSSRFSSVGA-CGIG------
--------GGYSGSF------SSSGFGGGLGSGFG-------------------------
-GR-FDGFGGGFGAGLGG--------GL---------------------------G----
----DGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLE---VKIRDWYQRQRPTE--
---V-KDYSSYFRTIEDLKNKIIIATQENA------------QSTLQMDNARL-AADDFR
T-KY-ENELFLRQSVENDINGLRKVLDELTLSRADLEMQIENLREELAFLKKNHE-----
-EMLSLRGQT-GGDISVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDVE---AWFLRK
----------------TEELN-KEVATKSDL--IESSRSEVAELRRVFQ---GLEIELQS
QLSMH---SSGQS---YSSREVFSSS----------------------------------
------------------------------------------------------------
-------------SHQPRSI----LK------------E--QG--STSFSQSQSQSSRN-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLG------
------------S-ALGS-NSYSSCYSFGTGS----------------------------
--------------GYGG-----NFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSAYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLSQIQGLIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSSTS----------SFGGL--
-G-------------------------GGSVC-------FGPGV-AFRAPSIHG------
---------------G-SG--------------GCGVSVSSARFVSSSS----S------
------------GG----------------------------------------------
-----------YGGDYGG-----I------------------------------------
LAASDGLLAGNEKFTTQNLNDRPASYLDKVRALEAANGELE---VKIRDWYQKQGP-G--
---PSCDYNHYYKTIQDLRDKILGATTENS------------RIVLQIDKVRL-AAGDFQ
T-KF-ETEQALHVSVEADINGLRRVLDEQTLARTDLEMQIEGLKEELAYLKKNHEE----
-ELSVLRGQV-GGQVSVEVDSALGTDLAKILSDMRSQYEVMAEQ-NRKDAE---AWFTSR
----------------TEELN-REVAGHREQ--LQMSNTEVSDLRRTLQ---GLEIELQS
QLSMK---AGLEGTLAETEVCFGAELAEIQARISGI-EAQLGDVRADSERQ--NQEYQRL
LDVKSRLEQEIA----TYHSLLEDQEDQTFINLCFSNAL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MATCSRQFTSS-SSMK---------------GS-
CGIGG-----------------SSS-RMSSVL---------------AGGSCRAP-----
---------------STYG---------------GMSV-TSSRFSSGGA-CGMG------
--------GGYGGSF----SSS-SSFGGGLGSVFGG--------------RF-----DGF
GGGFG------------G-----GLGSG------------------------------I-
---GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANTELE---VKIRDWYQRQRPTE--
---V-KDYSPYFKTIEDLKSKILAATVDNA------------NVLLQIDNARL-AADDFR
T-KF-ETEQSLRISVESDINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EMASMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENNLEETKGRYCMQLAQIQEMISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSS-SQFS--SS------SQ--FSSGSQSSR-
--------DVTSTNRQIRT-K---VM------------DVHDG--KVVST--HEQ-----
---------VLRTKN---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------GNEKITMQNLNDRLAAYLDKVRALEEANGELE---VKIRDWYQKQSPTS--
---PERDYSHYYKTIEELRDKILAATIDNS------------RVILEIDNARL-TVDDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKADLEMQIEGLKEELAFLKKNHEE----
-XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX---XXXXXX
----------------XXXXS-KEVATNTEM--MQTSKTEITELRRTLQ---RLEIELQS
QLSMK---AGLESSLAETECRYATQLQQIQGIIGSL-ETQLGELRCEMEQQ--SQEYNML
LDVKTRLEQEIA----IYRRLLEGEDAKM-AGVGSRG-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MSTQR-SSSKQYSS---SRS----GGGGG-G
-------------------GGGVSSLRISSSKCS-------------IGGGGL-----S-
SGGFSG-G---SF--SRGSSGGGCFGGSSG-GYGG--------------------GLGGF
GGGSFG--GGYGSSSF---S-------SCGGGSFGGGYG-------------GSSFG---
-GGGFGGGSFGGGGGFGG----GGFGGGSFGG-GGGF--------------GGGGF-GGF
--GDGGLLNGNEKVTMQNLNDRLASYLDKVRALEDSNYELE---VKIKEWYDKHGNV--G
RREP-RDYSKYYKIIEDLKNQIINLTVDNA------------NILIQVDNARL-AADDFR
M-KY-ENEVTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAYLKKNHEE----
-EMRDLQNVS-TGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEQ-NRRDAE---AWFNEK
----------------SKELT-TEINTNIEQ--VSSYKSEITELRRTIQ---GLEIELQS
QLALK---QSLEASLAETEGRYCVQLAQIQSQITAL-EEQLQQIRAETECQ--NAEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGFTHSGGRGGGS-------------------
----------------------------SGGGGGSYGGGSSG-G-GG-------------
------------------------GSYGGGSSGGGGGSYGGGSSGGGGGS----------
-YGGGSSGGGGGSYGG-GSSG----------------------GGGGSSGGLKSSSS-VS
IGE---QSSKGPRSAETSWGNQ-----------------N--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTSYSYRQ----SSAMS----------SFGGT--
-G-------------------------GGSVR-------IGSGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSIRLVSS-SSGS--------
------------------------------------------------------------
-----------YGGIRGG-----SFSG----T--------------------------L-
-AVSDGLLSGNEKITMQNLNDRLATYLDKVRALEQANGELE---VKIRDWHQKQGP-G--
---PSRDYNHYFKTIEELRDKILGATIDNS------------KIVLQIDNARL-AADDFR
T-KF-ETEHTLCLSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EITALRRQV-GGQVSVEVDSTPGVDLAKILSEMRSQYEIMAEK-NRKDAE---ATYLAL
----------------IEELN-TQVTISTEQ--IQISKSEITELRRTLQ---THEIDLQS
LLSTK---AALEGTLEETKARYGLVLSQIQSVISSL-EAQLSDVRAETERQ--NQEYKQL
MDIKSRLEQEIA----TYRSLLEGQEAHY-NNLPTPKA---I------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------MVPAIQQETIISATVDNN------------RMLLDIDNSKM-TADDFR
M-KY-ENELVIRQTVESDINGLRNMLDDLTLVRSSLESELESLKDELIALKRNHEE----
-ELRQLQSQT-GGDVSVEVNAAPGEDLTKILNDLRNEYEQIIEK-NRREVE---QWYEVK
----------------IEEVN-RQVTSSSQD--IQTSSHQLTELKREMQ---NLEIELQA
QLSTK---DSLENSLAETESRYGCLLQQIQGQINSV-EEELANIRCEMEGQ--SQEYKML
LGIKTRLEQEIA----QYRALLHEGQQDLAASQG--------------------------
----------------------------SF-Q---------G--------------GG--
--------------------K-SSQ-------S---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------Y----------------------------SSS--S-FSQ
SQSG-D------------------------------------------------------
---------------------------V--------------------------------
------T--GQS--------------------RVC-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MATTTTSIRQFSTS-GSIKG--------LCTPG----
----G-----------------GLS-RMSTVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGTMSA-ASSRFS-----AGLG------
--------GGYG-------G----GYTCSLGGGFGS------------------------
--------------SFGS-----AFG----------------------------------
--VSDALLGGGEKETMQNLNDRLASYLDKVRALEEANADLE---VKIREWYKKQGPGP--
---A-PDYSHYFKTIEDLRSKILAATIDNA------------SFVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNTEA--LQSNRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSI-EQQLCELRCDMERQ--NHEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSSSM-------------------ASQ
S-----TREGTVTSRQVRTI----TE------------EIQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSVRYSS-SKHYSS---SRS----GGGGGG-
-------------------GGGGSSLRISSSKGS-------------LGGGFS-----S-
-GGFSG-G---SF--SRGSSGGGCFGGSSG--GYG--------------------GL-GL
GGGSFG--GSYGSSSF---GG---------------------------------GYGGSF
GGGSFGGGSFG------G----GSFGG-------GGF--------------GGGFG-GGF
GGD-GGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE---GKIKEWYEKHGNS--H
QGQP-RDYSKYYKTIDDLKNQILNLTTDNA------------NILLQIDNARL-AADDFR
L-KY-ENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEE----
-EMKDLRNVS-TGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQ-NRKDAE---AWFNEK
----------------SKELT-TEIDSNIEQ--MSSHKSEITELRRTVQ---ALEIELQS
QLALK---QSLEASLAETEGRYCVQLSQIQAQISAL-EEQLQQIRAETECQ--NTEYQQL
LDIKIRLENEIQ----TYRSLLEGEGSSGGGGRGGGSYGGG-------------------
----------------YGGG----------SSGGGYGGGSSGGG-Y-------GGGHSGS
SGGGYGGG---SSGGGSSGGGYGGGSSSGGYGGGSS--------G---------------
------------GGHG-GSSGGG-------------GSSGGGFGGGSSGGGLKSSSS-GS
VGE---SSSKGPRY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSCS-------SRVSS---S-------KAGGSG
---------------SVRVSVGRSSF-SSGSKCGLGGSS----TRGFRGGT-S-----S-
----------------------CGLSGGSSSGFGGS-------------------VGGGF
GSCSVG--GGFGGSS---------GFGGGAS--FGGGS----------------G-----
---------FGRGSGFGG---GSGFGGSSGGG----FCSYGGG-------M----G-G--
GAGDGGLFSGGEKQTMQNLNDRLANYLDKVKALEEANTDLE---NKIKEWYDKFGPGSRD
SASG-RDYSKYYAIIEDLRNKIITATIENA------------GIVLQIDNARL-AADDFR
L-KY-ENELYLRQSVEADINGLRKVLDDLTMTRSDLEMQIESLTEELAYMKKNHEE----
-EMRSLQGSS-GGDVTVEMNAAPGTDLTKLLNGMRAQYEELAEQ-NRREAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKSEITELKRTLQ---ALEIELQS
QLAMK---SSLEGTLADTEAGYVAQLSEIQMRISSL-EEQICQVRGETECQ--NMEYEQL
LDIKTRLEMEIE----TYRRLLDGERGGS-------GFGGFDYKTS--------G-----
------------S-KNT----G--------------------------------------
------------------------------------------------------------
---------------------------------------------------SDDSRS-GN
C----SGQGRDP---SK----T-----------------RVTK-----------------
---------------TIIEEVVDGKVVSSQVSNI----SEVKV---------K-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------------------M-----SVRFS
SASRRLGS-GG--AGSVRFSSG---G-AGFGAGNACSV-PGIGSGF-SCAFEGSSSAGGY
GGG----------LV----GGSASCAAYTGNEHGLLSGNEKVTMQNLNDRLASYLENVRA
LEEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIEDLRNQIISATTSNAHV
VLQNDNARLTA-DDFRLKFENELALHQSVEADMNGLRRVLDDLTLCRTDLEIQLETLSEE
LAYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFNEKSASLQQQISDDAGATTSARNELTEMKRTLQ
TLEIELQSLLAM----KHSLECSLTETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCLLIDGEDGSCVKS----K--SYGGPGNQTK-DPSKTTMV
KTVVEEIDPRGKVISSRVHTMEEKSTKVINAKS--EQRVPS---------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-----SLRFS
SGSRSIHLRSG--IGSVRPSNG---G-AGFAGSNACGS-SVAGSGF-SCALGGGLG----
----SVPGGNHAGGA----LGG-ACAGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVHA
LEEANAELERKIKGRYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKTNI-SCTTANANV
ILQIDNARLAA-DDFRLKYESELALHQNTEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLRK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEDLAEQNRRDAEA--WFHEKSATLQQQISDDAGAATSARTELTEMKRTLQ
TQEIELQSLLAM----KHSLECSLSETEGNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCHLIDGDGNSCS----KSKGFGSGSSVNLSR---------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MPGP--------PLPRSIKPGIL--LTH
LSTFLF---PADSLTC-S-FTSLLGTMTTCSRQYTSS-SSIK---------------SS-
GGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------SAYG---------------GLSV-SSTRYSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GYGSGLGAGF
GG----GVGSGFGGG---------FGGG------------------------------Y-
GV-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPAE--
---T-KDYSPYFKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRLSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEVPDPLS------C----------PQ--LTP--SLLS-
--------SLVSSSRQVRT-K---VV------------DVHDG--KVV------S-----
---------THEQ---------------I--VRTKN------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGTLR-------VGG-G-GFGGGSLCG------
---------------G-GG--------------SRTISASSARFVSSGSGGGYG------
------------GG------M-SCGFGGGACSG---------------------------
---FGGGLGGGFGGSFGG-----GFG--------------------------------DY
GGGDGGLLSGNEKITMQNLNDRLASYLEKVRALEEANTELE---VKIRDWYQKQSPSS--
---PERDYSPYFKTIEELRDKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKADLEMQIEGLNEELAYLKKNHEE----
-EMKEYGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---GLEIELQS
QLSMK---TGLEGSLAETECRYATQLQQIQGLISSL-EAQLSELRNEMECQ--NQEYKTL
LDIKSRLEQEIA----TYRSLLEGQDARX-XXXXXXXXX---------------------
------------------------------------------------------------
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-------------------------------------------------M-----SFRFP
GGSRHNCLRAG--TGSVRPPSG---G-AGFAGSNACGS-SAAGSGF-SCTLGGGLG----
----SVPSGSHASGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKSWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKLISSTTANANV
ILQIDNARLAA-DDFRLKYENELALHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFNEKSATLQQQISDDAGAATSARNELTEMKRTLQ
TLEIELQSLLAT----KQSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDIKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVISSRVHSIEEKTSKVTNSKT--EQRVPF---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MASTTSIRQFSTS-GSVKG--------LCAPG----
----M-----------------GFS-RMSSVR--------------VGGA-CRAP-----
---------------SLLGG----------GSCGNMSV-TSSRFS-----AGLG------
--------GGYG-------G----GYTCSLGGGFGS------------------------
--------------SFG-------------------------------------------
--VSDALLGGSEKETMQNLNDRLATYLDRVRALEEANADLE---MKIREWYKKQGPGP--
---A-RDYSPYFKTIEDLRNKILAATIDNA------------SIVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNALRGQV-GGDVSVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNTEA--LQSSRTEITELRRSVQ---NLEIELQS
QLSMK---ASLENSLAETEARYGAQLAQLQGLISSV-EQQLCELRCDMERQ--NHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDAHLATQYSSS-L-------------------ASQ
P-----SREGMVTSRQVRTI----VE------------EVQDG--KVVSSREQVH--RS-
--------------------------------TH--------------------------
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--------------------------------------------------

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--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRA------
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGGGLGAGF
GGGL-G-------AGFGG-----GLGGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQT-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QGSSSFSQSQSS-
------S-----------------------------------------------------
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--------------------------------------------------

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-----------------------MSPEFGSCYRQ----SSVSS----------SIGGL--
-G-------------------------GGSLR-------FGAGG-PFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVSS--SGG--------
------------------------------------------------------------
-----------FGGGYAG-----ALA----------------------------------
--VSDGLLAGNEKITMQNLNDRLASYLDKVRALEEANGDLE---VKIRDWYQKQGP-G--
---PARDYSPYFNTIEDLREEVLGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EVSALRHQV-GGQVSVEVDSAPGIDLTKILSEMRSQYEDLAEK-YRRDAE---AWFTNE
----------------TVELN-QTVASHTQQ--LQVNETEVTELRRTFQ---GLETELQS
QLSMK---AALEGTLAETEARFGVQLAHIQGLITRI-EAQLSNLRADAERQ--NLEYQHL
MGIKLRLEQEIA----TYRSLLEGQDTHL-NSLATSKA---L------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTSYSYSQ----SSAKP----------SFGGLGR
----------------------------GSVS-------LGPRV-AFWAPTAAR------
---------------P-CP--------------APASCLSSSSL----------------
------------------------------------------------------------
-------------GGHSG-----V------------------------------------
LAASDGLLAGNEKLTMQNLNDGLASYLDKVRALEA----LE---VKIRDWHQKQGP-G--
---PSRDYSHYYKTIQDLRDKLLGATIENS------------RIVLEIDNARL-AADNFR
T-KT-ETEQALRMTVEADINGLSRVLDELTLASTDLEMEIEGLKEELAYLKKNHEE----
-EISRLRGQV-GGQVSVEVDSAQGTDLARILSDMRSQYKVMAGQ-NWKDVE---AWFTSR
----------------TEELK-REVAGHTDQ--LQMSLSKVTDLRHTLQ---GLE--LQS
QLSMK---ATLEGTLAETEARVGAQLAQIQPLINGI-EAQLGDVRADSEGQ--NQEYQQF
TDIKSRLQREIA----TYRSLLEGQEDHY-NTLSASKVL---------------------
------------------------------------------------------------
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--------------------------MTTCSRQFTSS-SSMKG--------SCGLG----
----G-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG---------------LSV-TSSRFSSGGA-CGMG------
--------GGYGGGF----SSS--SFG--------G--------------GLGGGLGVGF
GGGYG--------GGFGG-----GISVG------------------------------F-
GVGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPSE--
---I-KDYSPYFRTIEDLRSKIIAATMDNA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADINGLRRVLDELTLTRADLEMQIEGLKEELAYLKKNHEE----
-EMLALRGQT-GGDVSVEMNAAPGVDLSRVLNEMRDQYEQMAEK-NRRDVE---AWFLRK
----------------TEELN-KEVASNSEL--IQSGRSEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCAQLQQIQGLICSV-EEQLAQLRCEMEQQ--SHEYQVL
LDVKTRLEQEIA----TYRRLLEGEDSVSPPLL---SLSVFSSS----------------
-------------SRQPRPIL---KE------------QS-YS--QSQSSRN--------
------------------------------------------------------------
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--------------------------------------------------

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----------------------MSL-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSTCSTRFVSGGSVGGYG------
------------GG------I-SCGFGGGAGSAFGGGYG---------------------
-----GGLGGSFGGGFAG-----GFA--------------------------------DF
CAGDGGLLTGNEKITMQNLNDRLASYLEKVRALEAANTDLE---VKIRDWHLKQSPSS--
---PERDYSTYYKTIEELREKILSATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFTNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEAMAEK-NRRDAE---EWFHTK
----------------SAELT-KEVSTNTAI--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENSVAETECRYALQLQQIQGFISSI-EAQLSQLRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDSKM-TGFPSAGNVSPRSTSATTTA----------
-------S------AS-----V----------------TT-------T-----SGRRTS-
-------D-VRRP-----------------------------------------------
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--------------------------MTSYNYRQ----S-ATS----------SFGGL--
-G-------------------------GGALR-------FGAGG-AFRAPSIHG------
---------------G-SG--------------GRGVSISSARFLSSSSSGG--------
------------------------------------------------------------
-----------YGGGALL------------------------------------------
--SSDGLLAGNEKMTMQNLNDRLASYLDKVRDLETANGDLE---VKIRDWYQKQGP-G--
---PARDYDHYLKTIEDLRGQILDATIENS------------KVVLQIDNARL-AADDFR
T-KF-ETEQALHMSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEE----
-EISALRGQV-GGQVSVEVDSAPGVDLAKILSDMRSQYEVMAEK-NRKDVE---AWFASQ
----------------TEELT-REVAGHTEQ--LKMNKTEVTDLRRTLQ---GLEIEQQS
QLSMK---AALEGTLAETEARYGVQLAQIQALISSI-EAQLSDVRADTERQ--NLEYQQL
MDIKSRLEHEIA----TYRSLLEGQDALY-NNLPTAKA---L------------------
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---------------------------MATTFLQ-T--S---S----------TFGGS--
ST------------------------RGVSLR-------AGG-G-SFGGGSLYG------
---------------G-GG--------------SRSISASSARFVSSGAGGGFG------
------------GG------M-SCGFGGG----------------------FG-------
---------GGFGGGFGS-----GFG--------------------------------DF
GGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELE---VKIRDWYQKQSPAS--
---PDRDYSHYFKTMEEIRDKILAATIDNS------------RVVLEIDNARL-AADDFR
L-KY-ENELTLRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEE----
-EMKEFSSQL-AGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEK-NRRDVE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTLQ---GLEIELQS
QLSMK---AGLENSLAEVECRYATQLQQIQGVITGL-ETQLSELRCEMEAQ--NQEYNML
LDIKTRLEQEIA----TYRNLLEGQDAKM-AGIGVREASL---GGSSGG-----------
-------G-----SSNFHISVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
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---------------------------MTTTFLQ-TS-S---S----------TFGGG--
ST------------------------RGGSLL-------AGG-G-GFGGGSLYG------
---------------G-GG--------------SRNISASSARFVSSGSGGGYG------
------------GG------MRVCGFGGGAGSAFGG-------------G-FG-------
-AGIGGGFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQKQAPTS--
---PERDYSQYFKTTEELRDKIMATTIDNS------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLAKTDLEMQIEGLKEELAYLKKNHEE----
-EMKEFGSQL-AGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK-NRRDAE---AWFFSK
----------------TEELN-KEVASNTEM--IQTSKTEITDLRRTMQ---ELEIELQS
QLSMK---AGLENSLAETECRYATQLQQIQGLIGGL-EAQLSELRCEMEAQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-ADIGIREASS---GGGGS------------
-------------SSNFRINVE----------------ESVDG--KV----------VS-
------S--RKRE---------------I-------------------------------
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--------------------------------------------------

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----------------------MSV-RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSTRFVSGGSAGGLG------
------------GG------L-SCSFGGGAGSGFGGGFGG------GIGG----GFSGSF
GGGFGGSFGGG------------------------------------------------F
GGGDGGLLSGNEKITMQNLNERLASYLDKVRALEEANTELE---VKIRDWYQKQAPTS--
---PERDYSHYYKTIEELRDKILAASINNN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEVMAEK-NRRDAE---EWFQSK
----------------SAELN-KEVTSSTAM--IQSSKTEITELRRTLQ---GLEIELQS
QLSTK---AGLENSLAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKVL
LDIKTRLEQEIA----TYRSLLEGQDAKI-TGSTSAGGSVNIAVNGSSRR----------
-------T------RS--------------------------------------------
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--------------------------MTSYSYRQ----SSATS----------SFGGL--
-G-------------------------SGSLR-------FGAGG-NFRAPSIHG------
---------------G-SG--------------GRGVSVSSARFVTSSSSGS--------
------------------------------------------------------------
-----------YGGGYAG-----TLA----------------------------------
--GSDGLPAGNEKETMQNLNDRLASYLDKVRALEQANGDLE---VKIRDWYLKQGP-G--
---PARDYSHYFKTIEELRDKILGATIENS------------KIVLQIDNARL-AADDFR
T-KF-ETEQALRLSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISVLRGQV-GGQVTVEVDSAPGIDLAKILSDMRSQYEVMAEK-NRKDAE---AWFTTK
----------------TEELN-REVAGHTEQ--LQINKTEITDLRRTLQ---GLEIELQS
QLSMK---AALEGTLAETEARFGAQLAQIQALISSI-EAQLSDVRADTERQ--NQEYQLL
LDVKTRLEQEIA----TYRSLLEAQDVTH-QIV---------------------------
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---------------------------MSCS-------SRLTS---S-------RAGGSS
---------------SARVSAGGSSF-SSGSRCAIGGSL----ARGFQGGA-S-----S-
----------------------CGLSGGSSGAFGGS-------------------FGGAF
GSCSVG--SGLGGTSG-----SGAGFGGGSS--FGGVS----------------G-----
---------FGRGSGFCG---SSGFSGGAGGG----FCSYGGG-------M----G-G--
GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEQANTDLE---NKIKEWYDKFGPGSGD
SGSG-RDYSKYYPPIEDLRNQIIAATVENA------------GIILQIDNARL-AADDFR
L-KY-ENELCLRQSVEADINGLRKVLDDLTMTRSDLEIQIESLTEELAYLKKNHEE----
-EMKIMQDSS-GGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQ-NLQEAE---EQFNKQ
----------------SASLQ-AQISTDAGA--ASSAKNEVTELRRTLQ---AMEIELQS
QLAVK---SSLEGTLADTEAGYVAQLSEIQMQISAL-EEQICQIRGETECQ--NAAYEQL
LDIKTRLEMEIE----TYRRLLDGEGGGS-------SFAGFDGRNS--------G-----
------------S-TNM----G--------------------SR-D-------------L
V-----------------------------------------------------------
---------------------------------------------------PGDSRS-GS
C----SGQERDS---SK----T-----------------RITK-----------------
---------------TIIEELVDGKVVSSQVSSI----SEVKV---------K-------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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--------------------------MTTCSRQFTSS-SSMKG--------SCGLG----
----G-----------------GSS-R-VSIL---------------GGGSCRTP-----
---------------SAYGG----------SGFGGMSV-TTSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GYGSGAG---
------------------------------------------------------------
--------AGGEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---D-KDYSPYFRTIEELKNKILTATTDNA------------QTVLQIDNARL-AADDFR
N-KY-EHELVLRQTVEADINGLRRVLDELTLARTDLEMQIESLKEELVYLKKNHEE----
-EMNALRGQT-GGDVSVEMDAAPGINLSQVLSDMRDQYEQIAEK-NRRDAE---AWFLSK
----------------TEELN-REVASNSEL--VQSSKTEISELRRTLQ---GLESELQS
QLSMK---TSLENNLEETKGRYCLQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLSSQYT--SGQSSHT-SQEV--YL-----S--
----------RHSGHQIRPII---KE------------QTVTT--T------HSQSQRS-
------KH----------------------------------------------------
------------------------------------------------------------
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---------------------------MSTAFLETSS-SAFQG----------GLTW---
----------------------------RTSL-------WGWGG-GFGGGSLCG------
---------------L-GG--------------GRSVSACSTRFVSGGSAGGYG------
------------GG------M-SCGFGGGAGSGFGGGF----------------------
GGGFGGGLGSGFGGGFGG-----GFG--------------------------------DF
GGDDGGLLSGNEKITMQNLNDRLAAYLDKVRALEEANTDLE---VKIRDWHQKESPAS--
---PERDYSPYYKTIEEIRAQIMEGTIANN------------RVILEIDNARL-AADDFR
L-KY-ENELVLRQGVEADINGLRRVLDELTLARSDLEMQIESLNEELTYMKKNHEE----
-EMKEFSNQV-AGQVKVEMDAAPGMDLTRVLAEMREQYEAMAEK-NRRDAE---DWFNAQ
----------------SAELN-KEVTSSTTM--IQTSKTEITELRRTLQ---SLEIELQS
QLSMK---AGLESTVAETECRYAMQLQQIQGLISSI-EGQLSDLRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLIEGQDARM-TGVASGGGTVSGTTSSNASA----------
-------S------------------------------------------NAASGRRVS-
------DT-RRI------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------A------P-----
---------------SAYG---------------GLSV-TSSRFSSGGA-CGMG------
--------GSYGGGF----SSS-SSFGGGYGG--FA--------------GYG----GGL
GA----GLGAGLGGGLGG-----GFGVG------------------------------F-
GG-GDGLLAGSEKVTMQNLNDRLASYLEKVRALEEANAELE---VKIRDWYQRQRPVE--
---N-RDYSSYYKTIEDLRNKILTATVDNA------------NVVLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINALRRVLDELTLARADLEMQIESLKEELAYLRKNHEE----
-EMNTMRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRRDAE---EWFFSK
----------------TEELN-REVATNTEA--LQSSKTEISELRRSVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQDMIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------AQ--FSSGSQSSR-
--------DVTSSSRQVRT-K---VV------------DVHDG--KVV------S-----
---------SHEQ---------------I--LRTKN------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SFRLS
GGSRRVCLRA----SPGRLSSG---T-TAFGAGSACTG-TGAGSSF-ACSLGSVSS----
----GGAFG-NGGGG----LGGGLYKGLLGNEHGVFTGNEKVTMQNLNDRLASYLDHVQA
LEEANGDLEQKIKGWYEKYGP-ESLRELDRD---YS-RYFPIIEDLKKQIISLTNCNASI
VLQNDNARLTA-EDFKLKYENELALHQSVETDINSLHRLLEELTHCTTDLEIQCETLNEE
LTSLKT--NHEE----------------------EMKVLQSAAGGTVNVEMNAAPGVDLT
VLLNNMRAEYELLAEQNRRDAEA--WFDEKSASLQQQISVDEGAATAARNELTELKRNLQ
TLEIEFQSVMAM----KHSYESSLAETEGNYCLQLQKIQDQIRGLQEQLQQIRTETEGQK
MEYERLLDIKILLEKEIETYCKLMDGEESNCKV-GYKAKACLI-----ESQ-VSKEEIVV
KTVVEELDQRGNVLSLRVHSIEEKSSKISNITM--EQRVPSKAP------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MSC-RLQNSS-------FSYGG-GFGGGSCKL------
-----------------GG--------------GRSISSCSTRFVSG-SAGGYG------
------------GG------M-SCGFGG--------------------------------
--GFGGGIGGGFGGGFGG-----GFG--------------------------------DF
GGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSHYYKTIEELREKILAATIDNN------------RVILEIDNARL-AADDFR
L-KY-ENELALRQSVEADINGLRRVLDELTLSKTDLEMQIETLTEELAYMKKDHEE----
-EMKELNNQV-VGQVNVEMDATPGIDLTRVLAEMREQYEALAEK-NRRDAE---EWFQSK
----------------SAELN-KEVSSNAAM--IQTSKTEITELRHTLQ---SLEIELQS
QLSMK---AGLESSLAETECRYALQLQQIQGLISSI-ETQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEGQDAKM-TGFPSSGGNVSPGNANSASA----------
-------S------AS----------------------VA-------A-----SSRRVS-
-------DARRF------------------------------------------------
------------------------------------------------------------
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-------------------------------------------------M-----SLRFS
SGSRRSYARPSTGS--L----R---G-ASFGSGNTCGV-AGIGSGF-ACAFGSSS-TGGN
A------------------GVASSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSASYKSKDYGSGNAGNQIK-DSAKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MTTTTYRQYTSS-SSAKG--------S-SFG----
----G-----------------GSS-RPSSVH--------------VG-GGYQPS-----
---------------SIH------------GGLGGISV-SSSRYV-----SGVG------
--------SSLG-------GGYGG-------S------------------SYCSSYGGGF
GG------------GFGG-----GFGGG---------------------------S--FV
AGGSDVLLAGGEKETMQNLNDRLATYLDKVRALEHANTELE---VKIREWYQKRGPGP--
---Q-RDYSSYFRTIEDLRSKILAASVQNA------------TILLQLDNAKL-TADDFR
T-KY-ETEHALRTSVEADIHGLRKVMDELTLTRSDLEMQLENLKEELAYLHKNHEE----
-ELKVLRSQM-GGEITVEMDAAPGVDLTKILAEMREQYEHLAEK-NRKDAE---QWFFSK
----------------TEELN-QEVAINTEQ--LQSGKSEVIELRRTLQ---GLEIELQT
QLSMK---SSLEGTLAETESRYGLQLNQLQALITSV-EEQLAELRCDMERQ--NSEYKIL
LDVKTRLEQEIS----TYRRLLEGEEAHISSQYSS-------------------------
---------GPTTTRQVRTI----VE------------EVQDG--KVISSREQVH--VS-
--------------------------------GR--------------------------
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----------------------------------------------------------MS
L-------------------------RLQSSS-------ASYGG-GFGGGSCQL------
-----------------GG--------------GRGVSSCSTRFVSGGSAGGYG------
------------GG------V-TCGFGGGAGSGFGGGYGG--------------------
------GLGGGFGGGYAG-----GFV--------------------------------DF
GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLE---VKIRDWHLKQSPAS--
---PERDYSPYHKTIEELRDKILTATIENN------------RVILEIDNARL-AADDFR
L-KY-ENELTLRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEE----
-EMKEFSNQV-VGQVNVEMDATPGIDLTRVLAEMRAQYEAMAER-NRRDAE---EWFHAK
----------------SAELN-KEVSTNTAM--IQTSKTEITELRRTLQ---GLEIELQS
QLSMK---AGLENTVAETECRYALQLQQIQGLISSI-EAQLSELRSEMECQ--NQEYKML
LDIKTRLEQEIA----TYRSLLEDQDAKM-TGVPSSAGSVSPRSTSVTTT----------
-------S------SVS-VTTT----------------SN-------A-----SGRRTS-
-------D-VRRP-----------------------------------------------
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-------------------------------------------------M-----SLRLS
SGSRRSYARPSTGS--L----R---G-ASFGAGNACGV-AGIGSGF-SCAFGGSS-TGGN
T------------------GVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQA
LQEANADLEQKIKGWYEKFGP-GSCRGLDHD---YS-RYFPIIDDLKNQIITSTTSNANA
VLQIDNARLTA-DDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEE
LTYLKK--NHKE----------------------EMQALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--WFQEKSASLQQQITEDVGATTSARNELTEMKRTLQ
TLEIELQSLLAT----KHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQK
LEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYGSGNAGNQIK-DPVKAIVV
KKVLEEVDQRSKILTTRLHSLEEKSQSN----------------------

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-------------------------------------------------M-----SLRFS
NGSRHVCLRSG--AGSVRPPNG---G-AGFAGSSACGS-SVAGSEF-SCALGGGLG----
----SVPGGSHAGGA----LGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRA
LEEANAELERKIKGWYEKYGP-GSCRGLDHD---YS-RYHLTIEDLKNKIISSTTTNANV
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE----------------------EMKALQCAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRKDAEA--WFNEKSASLQQQISHDAGAATSARSQLTELRRTLQ
TLEIQLQSLMAT----KHSLEGSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK
LEYEQLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSSGNSSK-DLSKTTLV
KTVVEEIDQRGKVLSSRIHSIEEKTSKMTNGKT--EQRVPF---------

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--------------------------MTTTIRQFTSS-SSIKG--------SSGLG----
--------------------------GGSSR------------------TSCRLS-----
---------------GSLGA----------GSCRL-------GSA-----SGLA------
------------S-ALGS-NSYSSCYSFGTGG----------------------------
--------------GYGG-----SFG----------------------------------
--GVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE---VKIRDWYQKQAPGP--
---A-RDYSSYYHTIEDLKNKILVATVDNA------------SILLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEE----
-EMNALRGQV-GGEINVEMDAAPGVDLSRILSEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---ALEIELQS
QLSMK---ASLEGSLAETENRYCVQLAQIQGLIGGV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHLTQ---------------------------YK
P-------KEPVTTRQVRTI----VE------------EVQDG--KVISSREQVH-----
----------------------------------QTTR----------------------
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--------------------------MTTCSRQFTSS-SSMKG--------SCGIGGG--
--IGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYGG--------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFG----SGFGG--------------GYGAGFGAGL
GAGL-G-------G---------GFGGG------------------------------F-
AGG-DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPSE--
---I-KDYSPYFKTIEDLRNKIIAATIENA------------QPILQIDNARL-AADDFR
T-KY-EHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEE----
-EMLALRGQS-GGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK-NRRDAE---AWFLSK
----------------TEELN-KEVASNSEL--VQSSRTEVTELRRVFQ---GLEIELQS
QLSMK---ASLENSLEETKGRYCMQLSQIQGLIGSV-EEQLAQLRCEMEQQ--SQEYQIL
LDVKTRLEQEIA----TYRRLLEGEDAHLS-SQH-ASGQSYS--SREV--FTSSS--S--
----------SS-SRQTRPIL---KE---------------------QGSSSFSQGQSS-
------SN----------------------------------------------------
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--------------------------MTTCSRQFTSS-SSMK---------------GS-
CGIGG-----------------GSS-RISSVL---------------AGGSCRAP-----
---------------STYG---------------GLSV-SSSRFSSGGG-FGLG------
--------GGYGGGF----SSSSG-----YGGGFGG--------------GYGGGLGAGF
GG---------------------GLGAG------------------------------F-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE---VKIRDWYQRQRPTE--
---I-KDYSPYFKTIEDLRNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEK-NRKDAE---EWFFTK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTMQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQELIGSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTSSSRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
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-------------------------------------------------M-----SLRFS
GGSRHVGLQS----GSLRPPSG---G-AGFAGGSAGGS-SAAGSGF-SWALGGTLC----
----GGPGGSHAAGA----LGNAAGAGFTGNEGGLLSGNEKVTMQNLNNRLASYLDNVKA
LEEANTELERRIKNWHEKYGP-GSCRGLDND---YS-QYHLTIEDLKSKIISSTAANANI
ILQIDNARLAA-DDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEE
MTYLKK--NHEE-------------------------VGECAAGGNVNVEMNAAPGVDLT
VLLNNMRAEYEALAEQNRRDAEA--GFQEKSATLQQQISNDMDAVTSARSELTELKRSLQ
TLEIELQSLSAT----KHSLECSLAETEGNYCSQLAHIQAQISALEEQLHQVRTETEGQK
LEHEQLMDIKAHLEKEIETYCRLIDGDEN----SCSGSKGFESGSSGNSSK-DLSKTTLV
KAVVEEIDQRGKVLSSRIHSIEEKMSKMSNGKA--EQRVPF---------

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--------------------------MTTTIRQFTSS-SSVKGSGGGLGGGSCSIGGGS-
CGIGG-----------------GSS-RISSVL---------------AGGSYRAP-----
---------------SAYG---------------GLSV-SSSRFSSGGA-CGLG------
--------GGYGGGF----SSS-SSFGGALGSGFGG--------------GYGGGLGAGF
GG----G--------FGG-----GFGGG------------------------------L-
GG-GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANTDLE---VKIRDWYQRQRPTE--
---T-KDYSPYFKTIEDLKNKILTATVDNA------------NVLLQIDNARL-AADDFR
T-KY-ETELSLRMSVEADINGLRRVLDELTLSRADLEMQIESLKEELAYLRKNHEE----
-EMNSLRGQV-GGDVNVEMDAAPGVDLSRVLNEMRDQYEKMAEK-NRKDAE---DWFFSK
----------------TEELN-REVATNSEL--VQSGKSEISELRRTVQ---NLEIELQS
QLSMK---ASLENSLEETKGRYCMQLAQIQEMISSV-EEQLAQLRCEMEQQ--NQEYKIL
LDVKTRLEQEIA----TYRRLLEGEDAHL------SS---------SQ--FSSGSQSSR-
--------DVTS-SRQIRT-K---VM------------DVHDG--KVV------S-----
---------THEQ---------------V--LRTKN------------------------
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--------------------------MTTYSYRQ----SSATS----------SYGGL--
-G-------------------------GGSLR-------FGTGG-AFRAPSIHG------
---------------G-SG--------------GRGVSVSSARLVSS-VS----------
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-------------GGYGG-----GYGG----S--------------------------L-
-AVSDGLLAGNEKITMQNLNDRLASYLDKVRALEQANTELE---VKIRDWHQKQGP-G--
---PSRDYSHYFKTIEDLRDKIHGATIENS------------RIVLQIDNARL-AADDFR
T-KF-ETEQALRMSVEADINGLRKVLDELTLARTDLEMQIEGLKEELAYLKKNHEE----
-EISALRSQV-GGQVSVEMDSTPGTDLTKILSDMRSQYEVMAEK-YRKDAE---TRFISQ
----------------TEELN-REVAGHTEQ--LQAHTSEVTDLRRTLQ---GLEIELQS
WLSMK---AALEGTLAETEARYGAQLAQIQGKISSI-EAQLSDVRADTERQ--NQEYQQL
MDIKSRLEQEIA----TYRNLLEGQDTHY-NNVPGSKG---F------------------
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Query Results

"ENSGT00900000140820_0"

ENSGT00900000140820_0