Query Results 

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-------------------------------MTSSYSSS-SCP----LVC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDVGCQPGAE-ANVAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHS-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADQC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--R------------QAQHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------PSCVT----AP-----------------------------CA-
---PRSSC---------GP--YTTCG-----ASTTGSQF---------------------
----------------------------------------------------------

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--------------MDFSRR-----------------SFHRSLSNSLQASV---VS----
---TVG----------MQRLG----MTPSVYGGAGGRGIRISN-SR--HTVNYGSDLT--
--GG---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKM---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRTLEQSNS--KLEVQIK-QWYETN
APR--AGRDYSAYYKQIEELRNQ--IKDAQLQNARCVLQIDNAKLAAEDFRL---KY-ET
ERGIRLTVEADFQ-------------------GLNKVFEDLTLHK--TDLEIQIQELNKD
-LALLKKEHQEEVDGLYK--HLGNTV--NVEVDAAP------------------------
---------------------------------------------------GLNLGAIMN
EMRQKYEVM----AQKNL----QEAKEQFERQT--------------------AVLQQQ-
-VTV---NTEELKGTE-VELTELRR-TSQSLEID--LQS------------HLSM--KE-
-----SLEHTLEETKARYSSQLANLQSLLSSLEA--------------------------
QLMQIRSDMERQNNEYHILLDIK---TRLEQEIATYRRLLEGED---VR---------T-
------TE---------YQLST--------------------------------------
-----------------------------LEER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EENI--------------------------------------

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-------------------------------MTSSYSSS-SCP----LVC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDVGCQPGAE-ANVAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHN-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADMC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--R------------QAQHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------PSCVT----AP-----------------------------CA-
---PHPSC---------GP--CTTCG-----ASTTGSRF---------------------
----------------------------------------------------------

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--------------------------------------MASKCLKASFSSG-SLKSPGKA
-------------------GGGSTRTSTMY-SSSSC-KLPSLSRGARSFSVC--------
--------SAG--------------LGKNNYRISSCL---PALCLPS-GGFATSYST-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQVLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFRTMEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
EVSLRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWYDTQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNSLEIE--LQA------------QQSM--RD-
-----ALDSTLAETEARYGSQLAQMQCMIGNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
GNPCAPD----------YSPSKSCLPCLPAV-----------------------------
------SCSTGAARANCSPR-----PVYVPCSG-----GRF-------------------
----------------------------------------------------------

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--------------MAFSAR-----------------SIQWSSSSRVQPSA---PSISSL
TSRKMS----------VQKI-----QAPSVYGGAGGYGTRISTSSS--S--GLGGSLQLS
ITGS---DVLLAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKS---------------------------------TMQNLND---
-------------------------RLAAY-LE-RVRSLEKSNS--LIEKQIR-EWYEKN
TVS--IGQDYSSYFKTIEELRSK--IAEAQMENSRLVLQIDNAKLAADDFRL---KF-EN
EHLLRQSVESDIT-------------------GLLRVRDDLTLTK--ADLESQIESITEE
-LVFLRKNHEEERDRLRK--EAGGSV--NVAVDAAP------------------------
---------------------------------------------------GINLATIME
NMRKQYEEM----AEKYR----QEAKEHYEQQT--------------------AELHQE-
-VAL---NAELLEGQR-KEVTERRQ-VSQSLELE--LQS------------LLSM--KQ-
-----TLEGSVAETEARYSYQLDQIQQIISSLEA--------------------------
QLRQLRADMEAQNNQYSILMDVK---TRLEMEIATYRRLLEGEE---VG---------DL
EAI--------------ASITE--------------------------------------
-----------------------------AEK---ESSKFKKIKT----------IV--E
EVVDGKIVSSEVREI-EEKM--------------------------------------

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--------------MDFSRR-----------------SFHRSLSSSSQGPA---LSMSSS
VYRKGG----------AHRLV----AAPSVYGGAGGHGTRISV-SK--SVVSYASDLS--
--SG---GDLFAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKL---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRSLEQSNS--RLEFQIK-QWYETN
APS--TVRDYSPYYTQIKELQNQ--IKDAQIQNARCVLQIDNAKLAAEDFRL---KF-ET
ERGMRITVEADLQ-------------------GLSKVFDDLTLQK--ADLEVQIEELSKD
-LALLKKEHQEEVDVLRR--QLGNNV--NVEVDAAP------------------------
---------------------------------------------------GLNLGEIMN
EMRQKYEIL----AQKNL----QEAKEQFERQS--------------------EALQQQ-
-VTV---NTEELKGTE-IQVTELRR-TYQNLEIE--LQS------------HISM--KE-
-----SLERTLEETKARYASQLAAIQGMLSSLEA--------------------------
QLMQIRSDTERQNQEHNILLDIK---TRLEQEIATYRRLLEGED---VM---------T-
------TE---------YQLST--------------------------------------
-----------------------------LESR--DIKKTRKIKT----------VV--E
EVVDGKVVSSEIKEV-EESV--------------------------------------

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------------------------------------------MPYNCCL----PN-----
----ISC-RTS--------------CSSRPCLPPSCH---G-CTLPG-AC-NIPANVGNC
GWFC---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEGRIR-EWCQEQ
VPY--VCPDYQSYFRTIEELQQK--ILCTKAENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------SLRRILDNLTLCK--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QIGERL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRILN
ETRAEYEAL----VENNR----RDVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQNFQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLSQLQCMITSVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEIATYQGLLESED---CK---------LP
CNPCATT----------NACGKPIGPCPVS--------------------------N---
---PCVPCAP---CGPCAPR-S-RCGP----------------CN--------SFVR---
----------------------------------------------------------

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--------------------------------------MTSTCCV-TSNLQASLKSCP--
------------------------RPASVCSGSVNC-RPELCLGYVYQPMACLPSVCMPT
TFRPASCVSKT--------------YLSSSR-----W---PTS--------GISSAMGAG
SWYS---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LA-RVRELERENA--ELESRIQ-EASHSQ
VLT--MTPDYQSHFRTIEELQQK--ILCTKAENSRMVVNIDNAKLAADDFRA---KY-EA
ELAMRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LMCLKKNHEEGVGSLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRVLE
EMRCQYETM----VEANR----RDVEEWFNMQM--------------------EELNQQ-
-VAT---SSEQLQNYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLTESEARYSSQLAQMQCMITNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLESEINTYRSLLESED---C---------KLP
CNPCSTP----------SCNPCAPSP----------------------------------
----------CVSRTVCVPR--TVCVPCSPCPQ-----VRY-------------------
----------------------------------------------------------

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--------------------------------------MTSTCCV-TN---SSVKSCP--
------------------------QTSSACSGSVSC-RPELCLGYVCQPMACLPSVCVPT
TFRPASCLSKT--------------YLSSSCRPSSCW---PAS--------GVATTMGTC
GWYY---EGAFSG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------IMQSLND---
-------------------------RLACY-LE-KVRQLEQENA--SLESKIQ-EACQSQ
VVT--LCPDYQSYFRTIEELQQK--VLCTKAENARMVVHIDNAKLAADDFRT---KY-EA
ELAMRQLVEADIS-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEQEVSALRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRVLE
DMRCQYETM----VETNR----RDVEEWFNVQM--------------------EELNQQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RG-
-----SLENTLAETEARYGSQLAQMQGMIGNVEA--------------------------
QLAEIRCDLERQNQEYKVLLDVK---ARLECEINTYRGLLESED---C---------KLP
PNPCDTP----------ACAPCAPAP----------------------------------
----------CLPRTVCVPR--TVCVPCSPCPP-----GRY-------------------
----------------------------------------------------------

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-------------------------MLYAKPPPTIN----------------SIKGPQRK
ERLKPAHI----------HFQQLTCLSITSPST---------MSYSCCL----PS-----
----LSC-RTS--------------CSSRPCVAPSCH----GCTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1057)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEHLIQ-ERSQQQ
EPL--LCASYQSYFKTIEELQQK--ILCGKAENARLVVQIDNAKLASDDFRT---KY-QT
EQSLRQLVESDIN-------------------SMRRILDELTLCT--SDLEAQVESLREE
-LLCLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VDTNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLAQVQCLISNVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEINTYRS----------------------
------------------------------------------------------------
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-------------------------------MDTQGCTA-TISPS---------------
------------------------------------------TPPQNCSGITNFRAAS-S
-N------------NSCHH-------------------------SGPEGQGCCSTPCL--
------CCTPI--------------DLIGS-----FN----G-----------RPCPDSC
VWYW---EGI-NSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1064)

EKE---------------------------------AMQALNG---
-------------------------RLANY-LE-KVQKLEEENA--ALEGRIQ-EECTKE
LPI--LCPDYLSYYTIIEGLQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-ET
EVSVLQLVEADTS-------------------ALQQILDALALGK--ANLEAREQSLKEE
-LLGLKTSHEEEVSLLQC--QFGDRL--NIEVTAAP------------------------
---------------------------------------------------SVDLNQILQ
KLRCQYESL----METNR----KDVEQWFNSQM--------------------EELNQQ-
-VVT---GNLQQQCCQ-AELLELRR-TVNTLEVE--RQA------------QQQM--RD-
-----SQERILGETEARYTALLSQIQSLIHTLEA--------------------------
QLAEIRSALERQNQEYEILLDTK---SQLECEIATYRSLLESSD---G------K---LP
CEPCTTK----------SEPSM-----WARAR------------------------ECPA
L--VYTS---------PAL--TGTRK---TCGP--LPRILVKICT----------IT--M
EVKDGKVISSYEHVQ--------PCYITR-----------------------------

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------------------------------------------MPYNCCL----PA-----
----LSC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGSC
NWFC---EGSFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENC--ELERRIQ-ERNQQQ
EPL--LCPSYQSYFRTIEELQQK--ILCNKAENARLVVEVDNAKLATDDFRT---KY-ET
ELSLRHLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRSHEEEVNTL-RCQ-LGDHL--NIEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSLYEAL----VETNR----REVEEWYTMQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLNESEARYGSQLSQVQGLIGSVEA--------------------------
QLAEIRADLERQNQEYPGAADVR---ARLEGEISTYRGLLESED---CR---------LP
CNPCATT----------NTCSKAIGPCV-AN-----------------------------
---PCTPCPPPAPCTPCVPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

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--------------MDFSRR-----------------SFHRSLSNSLQPSV---VS----
---TVG----------MQRLG----MTPSVYGGAGGRGIRISN-SR--HTVNYGSDLT--
--GG---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKM---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRTLEQSNS--KLEVQIK-QWYETN
APR--AGRDYSAYYKQIEELRNQ--IKDAQLQNARCVLQIDNAKLAAEDFRL---KY-ET
ERGIRLTVEADFQ-------------------GLNKVFEDLTLHK--TDLEIQIQELNKD
-LALLKKEHQEEVDGLYK--HLGNTV--NVEVDAAP------------------------
---------------------------------------------------GLNLGAIMN
EMRQKYEVM----AQKNL----QEAKEQFERQT--------------------AVLQQQ-
-VTV---NTEELKGTE-VELTELRR-TSQSLEID--LQS------------HLSM--KE-
-----SLEHTLEETKARYSSQLANLQSLLSSLEA--------------------------
QLMQIRSDMERQNNEYHILLDIK---TRLEQEIATYRRLLEGED---VR---------T-
------TE---------YQLST--------------------------------------
-----------------------------LEER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EENI--------------------------------------

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--------M------------------------------TAAGSLVRGSPESCARDA---
----------------------------------GC-APA--------STCSPEATRLSS
AGPVSGCQASS--------------LLPGTHLSPGCP---APCYLAV-GC-DGGCLVENG
PWCE---DGAFNSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1069)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRCLEEANA--ELESKIQ-GQCEPD
ALV--VCPDYQCYFDTIEDLQQK--ILCTKAENSRLAVQLDNRKLAVDDFRS---RY-DS
ELSLRQLLENDIS-------------------GLRGILGELSLCR--SDLEAQVESLKDD
-LLCLKKSHQEEVSVLRA--QLGDRL--NVELDMAP------------------------
---------------------------------------------------TVDLNGALE
EMRRQYETV----LANNR----KEAEEWFSAQA--------------------EELSQQ-
-QLS---SAEQLQGCQ-VEILELKR-TANTLEIE--LQA------------QQNL--TD-
-----SLECTMAETEAQYSTQLAQMQGLIDNVET--------------------------
QLEEIRCDLERQNQEYQVLLDTK---ARLEQEIATYRRLLDRED---SR-----QVPQLA
SSPCSVV----------M-------PSSGNP-----------------------------
-------CEPGSAYILCTV--ENCCA----------------------------------
----------------------------------------------------------

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--------M------------------------------TSDCSSTHCSPESCTTAS---
----------------------------------GC-APA--------SSCSIETACLPS
ACATSRCHTPS--------------FLPRSRGLTGCL---LPCYFTG-SC-NSPCLVGDC
AWCE---DGVFTS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRSLEETNA--ELESRIQ-EQCEQD
IPT--VCPDYQCYFNTIEDLQQK--ILCTKAENSRLAVQLDNCKLATDDFKS---KY-ES
ELSFRQLLESDIS-------------------GLHGILDELTLCK--SDLEAHVESLKED
-LLCLKKNHEEEVNLLHG--QLGDHL--SVELDTAP------------------------
---------------------------------------------------TLDLNRVLD
EMRCQYETV----LANNR----REAEEWFAVQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSSQLAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLEGEINTYRGLLDSED---S---------RLS
CNPCSTT----------CT--------SSNT-----------------------------
-------CEPCSAYVICTV--ENCCL----------------------------------
----------------------------------------------------------

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------------------------------------------MPYNCCL----PT-----
----MSC-RTS--------------CSSRPCIPNSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEARIQ-ERNQQQ
DPL--VCPAYQSYFATIEQLQQK--ILCGKSENARLVVQIDNAKLASDDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNTLEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCMITNVES--------------------------
QLGEIRADLERQNQEYQVLLDIR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVSNP-----------------------------
----------------CVTR-S-RCGP----------------CN--------TFVR---
----------------------------------------------------------

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--------------------------------------MATQGCSPVFSSGSV-KGLCGT
-------------------AGGLSRVSSVR-SVGSC-RVPSLAGAV----------GSVS
SVRL------------------------GLSSLGSCL---PGSYLSA-GC-HPSGFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELERRIR-EWYESQ
IPY--ICPDYQSYFKTIEELQQK--ILLTKAENARLVLQIDNAKLAADDFRT---KY-ET
ELSMRQLVEADTN-------------------GLRRILDELTLCK--ADLESQVESLKEE
-LLCLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-NVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYGSQLAQMQCLIGNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLESEIATYRRLLEGED---C---------KLP
AHPCATE----------GKPSIRVPYVST-------------------------------
--------VPCAPA-----------VPCGPAPQ-----VSTQIRT----------IT--E
EIRDGKVVSSREHLQ-------------------------------------------

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------------------------------------------------------------
-------------------------------MDTKGCTT-TMSSS---------------
------------------------------------------APRRSCSRITDVRTIV-S
-H------------TSCRHGG---------LEANSC-QPMGHGLRNHLSQRCQPTPCF--
------GLPPL--------------CLINN-----CS----A-----------CPSLDDC
HWCE---EGI-HC

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1063)

KEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRMLERENA--ALECKIQ-EECDKE
LPV--MCPDYQSCYAIIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLRQILNALTLGE--ADLEAQVRSLKEE
-LLCLKTTMK---SSLQS--QLGERL--SIEV----------------------------
------------------------------------------------------------
--TCQYESV----VETNR----RDVEQWFCTQM--------------------EDLNQQ-
-VAT---STQQQQCCQ-REIIELRS-TVNALENE--LQA------------LHRM--RD-
-----SQEWALAETEARYAALLAQIQRLIDNLEA--------------------------
QLAEIRGALERQNQEYEILLDIR---SRLECEITTYRSLLERSD---G------K---LP
CHPCATK----------YQPST-CTSSKTRAV------------------------EHTA
R--PHTPP--------SDP--CGIPEARAACRD--LSRILIKICT----------TT--K
EIKDGKVISSHEHVQ--------PCFITRTAKA-------------------------

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------------------------------------------------------------
-------------------------------LDTKGCTT-TMSST---------------
------------------------------------------TPCQSCSGITNLTTIL-P
-N------------TSCQHGG---------LKANSC-QPTGHVLRTLQSLDYRPTPGF--
------SLTPL--------------CLISN-----FN----T-----------CPFLDDC
GWCD---GGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKE---------------------------------TMKILNN---
-------------------------RLANY-LE-KVQMLERENT--ALECKIQ-EECNKE
LPV--ICPDYLSYYATIEELQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-EA
EMSLRQLVEADAN-------------------GLQQILNALTLGK--ADLEAQVQSLKEE
-LLCLKNDHEQEISSLQN--QLGDRL--HIEVTSAP------------------------
---------------------------------------------------SVDLNRVLQ
EMRCQYESI----METNR----KDVEEWFNTQM--------------------EELNQQ-
-VVT---STQQQQCYQ-KEITELRR-TMNALEVE--LQA------------QHRM--RD-
-----SQECALTETEARYAALLAQTQCLIDNLEA--------------------------
QLAEIRGALERQNREYEILLDVK---SRLECEIATYRSLLESSD---G------K---LP
CHPCAIK----------HESSA-CISNKARTM------------------------ECTA
P--AHTS-S-------LGP--CGIHESHSAWSI--LPRILVKICT----------IT--E
EIKDGKVISSYEHVQ--------PCFITRAAKA-------------------------

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGHTT-TNSPS---------------
------------------------------------------TPCQSCSRITNVSNIS-A
-N------------NSCQC-G--G------LKVNNR-HPAGHVQRIFQDQGCQPTRCS--
------CCMPI--------------YLVNN-----FN----A-----------RSSLDYC
SWYS---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNN---
-------------------------RLANY-ME-KVRMLERENA--ELESKIQ-EESNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---KY-EA
EASLRQLAEADAN-------------------GLKQILNVLTLGK--ADLEVQVQSRKEE
-LLCLKNNHEEEINSLQC--QLGERL--HIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCRYESI----METNR----KDAEQWFSAQM--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEVD--LQA------------QHRM--RD-
-----SQECILTETEARYTALLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEITTYRSLLESLD---G------K---LP
CYPCATK----------CEPSP-WTSCKSRAM------------------------ECTA
P--ACTS---------SAS--CGLQGPCSACGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

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-------------------------------------------MT-SNCS-ASIKSCP--
------------------------RPSSVCSSSMSC-RPEMCLGYVCQPVSCVPSVSVPT
TYRPASCFSKT--------------YLSSSCWSSSCR---PSS--------GISSSMGTC
SWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQSLND---
-------------------------RLACY-LE-KVRQLERENA--ELESKIQ-EACQSQ
VAT--MSPDYQSYFRTIEELQQK--VLCTKAENARMVVHIDNAKLAADDFRT---KY-ET
ELTMRQLVEADTN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKKNHEQEVSALRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLNRMLE
EMRCQYETV----VEANL----RDVEEWFNTQM--------------------EELNQQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLESTLAETEARYGSQLAQMQCLISNVEA--------------------------
QLAEIRCDLERQNQEYKVLLDVK---ARLECEINTYRGLLESED---C---------KLP
CNPCSTP----------SCPPCAPSP----------------------------------
----------SMPRTVCVPR--TVCVPCVPCPQ-----SRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSSG-SLKVPGGA
-------------------GGGSARVSTIF-SSSSC-KLPSFSRGPRSFSAC--------
--------SVG--------------LGKSSCRAASCL---PALCLPS-GGFATSYGM-AG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIH-EWCEQQ
VPY--LCPDYQSYFQTIEELQKK--TLCTKSENARLVVQIDNAKLAADDFRT---KY-ET
EVSMRQLVESDMN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLN
EMRCQYETL----VENNR----REAEDWFNTQT--------------------EELNQQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQMQGLIGNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRGLLDSED---C---------KLP
CNPCAPD----------HSPSKSCLPCLPAA-----------------------------
------SCGPGMARTTCSPR-----PICVPCPG-----SRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------R---TFG----------
------------------------------------------------------------
--S--SGF----IR--SGRLLE-PQAASMCFSAAMAHNNRVRVGT---TSLGRPSLCLPN
SCWS-AC------------------------------------PLPG-AV-NIPANIGNC
GNYG---EGFLNSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRELERENA--ELETKIQ-EWSKCH
PSF--VCPDYQSYFRTVEELQQ--KILCTKSENTRLVVQIDNAKLAADDFRT---KY-ET
EHSLHQLVEADIG-------------------SLRRNLDDLTLAK--CDLEAQLESLKEE
-LLSFKKNHEQEVQNLHR--QLGDKL--HIELDTAP------------------------
---------------------------------------------------PVDLNRVLG
EMRCQYEAM----VETNQ----NDVEQWFLAQS--------------------EGISMQ-
-EMS---CSEEIQCCQ-SEILELKR-SVDALEVE--LQA------------QHKL--KE-
-----CLENSLCESEARYSTELAQMQYLISNVEE--------------------------
QLSEIRADLERQNNEYQVLLDAK---ARLECEISTYRNLLESED---C------K---LP
CNPCANS----------VSCVP-----------------------------------CP-
---PPAACAS---CLPSAP--RSICAPCSSSRC---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------ASNCGPPKCSSAT-SKSHSRL
-P----I-------------------SRALSASTSC-QPKSCQINRCGGP---SNVCHPV
P-----YRSLI--------------YLLNN-----FR----P-------------SVASC
G------EGNFDS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMQMLNQ---
-------------------------RLANY-LE-KVRSLEEENV--YLECKIQ-EHHEKQ
TPM--VCPDYLSYFKIIEELQQK--ILCTKAENSRLVSQIDNTKVIADDFRA---KY-ET
EVAQRQLVETDIN-------------------SLHQILNKLTLCK--ADLEGRVESLKEE
-LLHLKHNHEEEVNSLQC--QLGDRL--NIEVNAAP------------------------
---------------------------------------------------SIDLNEALQ
KMRCKYESL----VETNR----RDVEEWFNTQL--------------------QELNQQ-
-VVS---SSEEQQCFQ-KEICDLRR-TISALEIE--LQA------------QHSL--RD-
-----SHECILTETEGRYAIQVAQIQCLIENLES--------------------------
QLAEIRCTLDRQNQEFQVLLDVK---SKLECEIATYQHLLENTD---C------R---LP
CNPCVTE----------RKPSP-CMPCISQTL------------------------ECTS
P--AYVTCRPC---NSSIC--NVRANPCNFCSS--LPAILARIYT----------LT--Q
EFQDGKVISSREHVQ--------PCYI-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTTQLCTPAFSTGSG-RAFCGT
-------------------AGGFSRVSSFR-SGGSC-RVPGLAGAV----------GSGS
SFRL------------------------GLSGPGGFL---PGSCLST-GG-HPSGFVGSG
GWLC---EGSFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1061)

NEKE---------------------------------TMQFLNE---
-------------------------RLASY-LE-KVRELERANC--ELEGRIR-EWYECQ
SPY--ICPDYQGFFRTVEELQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-DT
ELSLRQLVEADIN-------------------GLRRILDELTLCR--ADLEAQVESLKEE
-LLCLKRNHEEEVNALRG--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DVRCQYEAL----VENNR----RDVETWFNAQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYGSQLSQMQGLIGNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDTK---ARLEQEIATYRCLLDRQ---PCV----TSFFRLP
AHPCSME----------CKPAVRGPCILP-------------------------------
--------GPCTPA-----------APCVAAPQ-----VSTQIRT----------IT--E
EIRDGKVVSSREHVV--------PCPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDCPPTDCPSEPCARA----
--------------------------------------SA--------STCSVEMKCLPS
ACAASRCHTPS--------------FLPRSRLLTGCL---MPCYLAG-SC-NSPCLVGSC
AWCE---DGVFTS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRTLEETNA--ELECQIR-EQCEQD
TPL--ACPDYQHYFDAIEELQQK--ILCTKAENSRLAVQLDNCKLATDDFRS---KY-EN
ELSLRQLLEADIS-------------------GLRGILDELTLCK--SNLEAHVESLKED
-LLCLKKNHEEKVGLLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TLDLNRVLD
EMRCQYETV----LANNR----RDVEEWFTIQT--------------------EELNQQ-
-QLS---STEQLQGCQ-TEILELKR-TVNALEIE--LQA------------QQSL--TE-
-----SLECTMAETETQYSSQLAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDVK---AQLESEITTYQGLLDSED---C---------RLP
SNPCSTT----------CT--------SSNT-----------------------------
-------CEPCSAYVICAV--EKCCS----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MSFSAQ-----------------SFQLGTTARLQGTA---PGSSAL
SVRNAA----------VQRI-----QAPSVYGGAGGYGTRVSSSSV--RRQSTGGAFYSN
ISDN---DLLLSG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKS---------------------------------TMQNLND---
-------------------------RLAAY-LE-RVRSLEKANS--LLEKQIR-EWHEKN
TGG--IRSDYSSYFQTIEDLQSK--ISAAQMENAKLVLQIDNAKLAADDFRL---KF-EN
ELLLRQSVESDIN-------------------GLLRVLDDLALTK--SDLESQIENVNEE
-IVFLKKNHEEEVDRLRK--QVGGSV--NVEVDAAP------------------------
---------------------------------------------------GTDLSSIME
NMRRQYEEM----AEKNR----QEAKERFEKQT--------------------EALNQE-
-VAI---NVEQLQEQR-REVTDRRQ-ICQSLELE--LQT------------NLNM--KK-
-----SLEDTLAETEARYSFQLAQIQETIARLEN--------------------------
QLRQLRADMEAQNTEYSILLDIK---TRLEMEIATYRRLLEGED---IG---------FV
QEE--------------VLTND--------------------------------------
-----------------------------LEKA--ESSKIKKIKT----------IV--E
EVVDGKVVSSQVKEI-EEKM--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEHLIR-ERSQQQ
EPL--LCASYQSYFKTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKSNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNQVLN
QTRSQYEAL----VDTNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQSLISNVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CN---------LP
SNPCATT----------NACSKPIGPCVSNPC------------------------T---
------PCVPPAPCTPCAPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YAKPPPTVN----------------SIKGP---
--LKPAHI----------HLQQLTCFSITCPST---------MSYSCCL----PS-----
----LGC-RTS--------------CSSRPCVPPSCH----GHTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFTIIEELQQK--ILCAKAENARLVVNIDNAKLASDDFRS---KY-QT
EQSLRRLVESDIN-------------------SIRRILDELTLCK--SDLESQVESLREE
-LICLKKNHEEEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CNPCATT----------NASGNSCGSCGTS------------------------------
Q--KCC-CN---------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSSCCV-TNNLQASLKSCP--
------------------------RPASVCSSGVNC-RPELCLGYVCQPMACLPSVCLPT
TFRPASCLSKT--------------YLSSSC-----Q---AAS--------GISGSMGPG
SWYS---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LT-RVRQLEQENA--ELESRIQ-EASHSQ
VLT--MTPDYQSHFRTIEELQQK--ILCTKAENARMVVNIDNAKLAADDFRA---KY-EA
ELAMRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVGSLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRVLE
EMRCQYEAM----VEANR----RDVEEWFNMQM--------------------EELNQQ-
-VAT---SSEQLQNYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLTESEARYSSQLAQMQCMITNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLEGEINTYRSLLENED---C---------KLP
CNPCSTP----------SCTTCVPS-----------------------------------
---------PCVPRTVCVPR--TVGMPCSPCPQ-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------ASDCSPTGCSSESSARAS---
----------------------------------DC-ALA--------STCSAATTCLPS
ACATSSCQTPS--------------FLSGSRLPTGCL---PPSCFAG-SC-NIPCVLGNC
AWCE---DGAFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRGLEELNA--ELECRIR-EQSEED
VPL--VCPDYQCYFDTIEDLQQK--ILCTKAENCRLAVQLDNCKLAADDFRSKYKRY-ES
ELSLRQLVETDIS-------------------GLHGILGELTVCR--SDLEAHVESLKDD
-LLCLKKSHEEEVNVLRG--QLGDRL--SVELNTAP------------------------
---------------------------------------------------TTDLNRVLD
EMRCQYETV----LANNR----RDVEEWFAVQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSSELAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDTK---ARLECEINTYRGLLDSED---S---------RLP
CNPCSAT----------ST--------SNNT-----------------------------
-------CEPCSAYIICTV--ENSCP----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATPICIPSISAGSV-NGLCGT
-------------------AGGISRLSSVR-SMGSC-RVPSLACAG----------GSFS
SVRL------------------------G-SGLGSSL---PGSFLSS-GF-HPSGFVGSV
GWLG---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEGRIR-EWYESQ
VPY--ICPDYQSYFKTIEELQQK--KLLINAENARLILQIDNAKLAADDFQV---KY-EM
ELSARQLVEADIN-------------------GLRRILDDLTLAK--ADLEMQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYETL----VENNH----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QLSM--RN-
-----SLESTLAETEARYSSQLAQMQCLISNVEA--------------------------
QLAEIRCDLERQNHEYQVLLDVK---ARLESEIATYRGLLEGED---C---------RLP
PHPCATE----------CKSVVRTPYISS-------------------------------
--------TPCAPT-----------VPCAPAPQ-----ISTQIRT----------IT--E
EIRDGKVISSREHLL--------PCPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----SN-----
----MSC-RST--------------CSSRPCVPPSCH---S-CTLPG-AC-NIPANVGNC
NWLC---EGFFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMHSLND---
-------------------------RLASY-LE-KVRQLERENA--ELESLIQ-ERCQPQ
EPL--LCPSYQSYFRTIEELQQK--ILCGKSENARLVVQIDNAKLASDDFRT---KY-ET
ERSLRQLVEADIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLYLKQNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAV----VETNR----REVEEWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCMITNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
SNPCATT----------NACEKPIGPCVANPC------------------------V---
------QR----------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDCSSTHCSPESCTTAS---
----------------------------------GC-APA--------SSCSIETACLPG
ACATSRCQTPS--------------FLSRSRGLTGCL---LPCYFTG-SC-NSPCLVGNC
AWCE---DGVFTS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRSLEETNA--ELESRIQ-EQCEQD
IPM--VCPDYQCYFNTIEDLQQK--ILCTKAENSRLAVQLDNCKLATDDFKS---KY-ES
ELSFRQLLEADIS-------------------GLHGILDELTLCK--SDVEAHVESLKED
-LLCLKKNHEEEVSLLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TLDLNRVLD
EMRCQYETV----LANNR----REAEEWFAVQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSSQLAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLEGEINTYRGLLDSED---S---------RLS
CNPCSTT----------CT--------SSNT-----------------------------
-------CEPCSAYVICTV--ENCCL----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MTSSYSS-SSC-----------------
-----------------------------------------PLVCTMAPGTRNVSVSPID
--------------VGCQPR-----------------AEA---NV--------APMCLLA
NVAHAN----------RVRVGSTPLGRPSLCLPPTCH---NACPLP--GTCHIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 731)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLR-ERSKCH
EST--VCPDYQSYFRTIEELQQK--ILCSKTENARLIVQIDNAKLAADDFRI---KL-ES
EHSLRQLVEADKC------------------G-TQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQVWPWPLR--LPGRA-----------------------------------
------------------------------------------------------LGRQG-
--------------NQPP----GCLEQWFQAQV--------------------NGRRYS-
-KQASDSCSGGAASAASREILEPES-TVNALWRV--RSA------------------KA-
-----QPHTLVCTC-LQNSLVLKAERTLISNVEE--------------------------
QLSEIRAGPGAAEPASTRVLPGREGPRAAENEIATYRNLLESED---CK---------LP
CNPCST-P---------ASCTSCPSC---G------------------------------
---PVTGG---------SP--SGHGAS--------MGR----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSECPPKSDTPESCSKAS---
----------------------------------DH-SSV--------STHSTEIPCLPS
TGVTSRCQTPT--------------FFARSCQPTSCL---ATCYLHG-SC-NIPCVVGSC
GWGE---EGVFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLACY-LE-RVRGLEQENA--ALECKIR-EQCEPE
VPL--MCLDYQCYFDTIENLQQK--ILCTKAENSRLAVQIDNFVLAVDDFRS---KY-EA
ELSLRQQAEADIK-------------------GLRKILDDLTLCK--CDLEAHVESLKED
-LLSLKKNHDEEVCLLKE--QLGDRL--NVELDTAP------------------------
---------------------------------------------------PVDMNKVLD
DMRCQYEMV----VADNR----RDVEQWFTLQT--------------------EELNQQ-
-QLS---SSEELQCCQ-SEVLELKR-TANALDIE--LQA------------QHGL--IE-
-----SLECTQAETEAQYSTQLAQMQCLIDNVES--------------------------
QLAGIRCDLERQNQEYQVLLDMK---ALLECEIATYQSLLESED---S---------KLP
CNPCSSS----------TT--------SGNT-----------------------------
-------CEPCTACLICTV--EGCQV----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSCISS-RHS----LGC----------
------------------------------------------------TNTPGARNI---
--C--VSS----TDTGDQLGAE-ISAALLGLSATLAHANRVRVGT---TPLGRPSLCLPH
SCNT-AC------------------------------------PLPG-TC-DIPGNIGIC
GTFG---EGFFNSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRGLERDNA--ELESRIQ-ELSKCP
EST--VCPDYQSHFCIIEELQR--KILCVKSENNKLVVQIDNAKLAADDFRT---KF-QM
EHSLRQLVEADVC-------------------GMRRALDDLTLAK--ADLEAQVESRKEE
-LLCLKKNHEQEVHTLKR--QLGDKL--KIELDVEP------------------------
---------------------------------------------------TVNLGRVLE
EMRGQYEAV----VETNL----RDVEQWFQTQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRR-TVNTLEVE--LQA------------QHTL--KD-
-----CLQNSLCESEARFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLEGEIATYRNLLEKED---C------K---LP
CNPCATP----------VSITC----V-----------------------------GPS-
---ACTSCSPCLS----GP--SGSCSSPRC------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSCISS-SHC----LGS----------
------------------------------------------------TRTFGARNV---
--S--VCS----SDVGDQPGAE-AKAASLCLSATQAHTNRVCVGT---TPLGRPSLCLPH
SCNA-AC------------------------------------PLPG-TC-DIPGNIGTG
GTYG---ESTLNSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKV---------------------------------TMQFLNN---
-------------------------RLANY-LE-KVRQLERDNE--ELETKIL-ESSKCH
ESS--VCLDYQNYFRTMEELQQ--KILCSKAENARLIIQIDNAKLAADHFRI---KH-ES
ECALRQLVESDMC-------------------GMHKLLDDLSLAK--ADLEAQQESLKEE
-LLCLKSNHEQEVSSLKS--QLGDKL--RIELDTEP------------------------
---------------------------------------------------PVDLGRVLG
EVRCQYEAM----VETNH----RDVEQWFQAQS--------------------EGISLQ-
-ATS---CSEELRCCQ-SEILELRR-TVNALEVE--RQA------------QHNL--KD-
-----GLQNSLCEAEARYGTELAQIQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLEGEIAMYRNLLENED---C------K---LP
CNPCSTP----------ASCAL----R---------------------------------
-----PRC---------GP-----------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTSD-----SSPSACLS--EPCSGTSGHASASTCSVE-TTRLS----S----------
-------TC---------------------------------------------------
-------------------A------TSRCQ---TP-SLLSRSH---LLTSCLTPCYFTG
-----SC---------------------------------------N-S----PGLVGNC
TWCE---DGVFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRSLEETNA--ELECRIQ-EQCEQD
IPL--VCPDYQCYFATIEDLQQK--ILCTKAENSRLAVQLDNCKLAADDFRS---KY-ES
ELSLRQLVETDIS-------------------GLRGILNELNLCK--SNMEAHVESLKDD
-LLCLKKNHEEXXXXXXX--XXX--X--XX-XXXXX------------------------
---------------------------------------------------XXXXXXXXX
XXXXXXXXXXXXXXXXXX----XXXXXXXXXXX--------------------XXXXX--
-XXX---XXXXXXXXX-XXXXXXXX-XXXXXXXX--XXX------------XXXX--TE-
-----SLECTVAETEAQYSTQLAQMQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYDVLLDTK---ARLECEINTYRGLLERED---S------RVPQLP
CNPCSTT----------CTSSNA------------------------------------C
EPCSAYVI------------C---------------TVENCCV-----------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYNFCL----PN-----
----LSF-RSS--------------CSSRPCVPSSCC----GTTLPG-AC-NIPANVGSC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIL-ERSQQQ
EPL--VCPNYQSYFRTIEELQQK--ILANKAENARLVVQIDNAKLAADDFRVACARY-QT
ELGLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LICLKQNHEQEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRAQYEAL----VETNR----RDVEEWYIRQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEVE--LQA------------QHNL--RD-
-----SLENTLTETEARYSCQLSQVQSLIVNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLESEINTYRGLLDSED---TK---------LP
CNPCATT----------NASS--VGSYVTNP--------------------------C-T
P--CG-------------PR-S-RFGP----------------CN--------TSGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MP--Y
-SCS-LPS------LSCS---------------SSC-FSRPCVPRSCHGS----------
-------------------------------------------TLPG-SC-NIPANVGNS
GCFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 749)

NEKE---------------------------------TMQFLNS---
-------------------------RLANY-QE-KVRQLERDNA--ELESRIW-EQSQQQ
YPL--VCPDYQSRFRTIEDLQQK--XXXXXXXXXXXXXXXXXXXXXXXXXXX---XY-ET
EVSLRQLVEADLK-------------------SLSRILDEPTLCK--SDLEAQVESLKEE
-LILKNH--EQEANSLRR--QLGDRLNEE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLRS------------------------GLSGLGSCL---PGSYLSS-GC-HSSGFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWYESQ
IPY--ICPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------SLRRILDELTLCK--ADLEAHVESLKEE
-LMCLKKNHEEEVSVLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILE
DMRCQYEAL----VENNL----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNTLEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRRLLEGED---C---------KLP
PPPCAMA----------CKPAIRVPSVPL-------------------------------
--------VPCAPA-----------VPCTSAPQ-----VGTQIRT----------IT--E
EIRDGKVISSREHLQ--------SHLL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MPISRG-----------------KFIRSNSNEAI--------FINP
VFRMPA----------KQ-VF----YTPSVYGGAGGWGTRIST-ST--TQIQYGEGLG--
---A---GKLLTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKG---------------------------------TMQNLND---
-------------------------RLANY-LE-KVRSLQQANS--KLEVQIR-QWHEKN
STP--LGRDYRSYYKAIEELQEQ--IKNAQINNAQLVLQMDNAKLAAEDFRI---KY-ET
ELGMRLSVENDIQ-------------------GLNKVTDDLTLKK--ARLESEIENLTEE
-LVLLRKNHEEEVDTLRK--HLGATV--KVEVDAAP------------------------
---------------------------------------------------GPDLGAIIN
EMRDKYESL----AKKNI----QKAKERYETQT--------------------IELETQ-
-ITL---NNRELETST-TQVKELRR-KCQNLEME--LQS------------LLSQ--RD-
-----SLDLTLAETNTRYEARLAQLQAVLKALKD--------------------------
QLIQVRSESEKQRDQFNTLLDVK---NRLEQEIITYRRLLEGED---IV---------T-
------LD---------SETTT--------------------------------------
-----------------------------LEER--DAKKIRKIRM----------VV--E
EVVDGKIVSSKTKEM-EETL--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKAGFSSR-SLKGPGGA
-------------------SGGSTPVSAMY-SSSSC-KLPSLSRGARNFSAC--------
--------SAG--------------LGRSSYGAVSCL---PTLCLPA-GGFTNSYSM-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIR-EWCEKQ
VPY--MCPDYQSYFQTIEELQKK--TLCSKAENARLVVEIDNAKLAADDFRT---KY-EM
EVSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNQQ-
-VVS---SAEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQMQSLITNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEISTYRGLLESED---S---------KLP
CNPCAAD----------YSPSKSCLPCLPAA-----------------------------
------SCGPSAARTTCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSAG-SLKSPGGA
-------------------RGGSPRVSAVY-SSSSC-KLPSLSRGARSFSVS--------
--------SAG--------------LGRSSYRVASCL---PALCLPA-GGFATGYGA-GG
GWYG---EGVLTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQLLND---
-------------------------RLASY-LE-KVRQLEQENT--SLESRIR-EWCEQQ
VPY--MCPDYQSYFQTIEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
EVSLRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AELIELRR-TVNALEIE--LQA------------QQSM--RD-
-----ALESTLAETETRYGSQLAQMQCMISNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLEGEISTYRGLLESED---C---------KLP
CNPCAPD----------YSPSKSCLPCLPAA-----------------------------
------SCSPGVVCAASSPR-----PVCVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTSP-----SSIKSCPRPSSVCSNN-------MACRP-ELCLG----Y----------
-------IC---------------------------------------------------
-------------------Q------PMTCV---PS-VCMPTTY---RPASCLPKTYLSS
-----SC-----------------------------R-------AAA-G----SSSMGTC
SWLC---EGPFSG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQVLND---
-------------------------RLANY-LE-KVRQLEQENA--SLESKIQ-EACQSQ
VPT--MCPDYQSYFRTIEELQQK--VLCTKAENARMVVHIDNAKLAADDFRT---KY-ET
ELAMRQLVEADTN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKKSHEEXXXXXXX--XXX--X--XX-XXXXX------------------------
---------------------------------------------------XXXXXXXXX
XXXXXXXXXXXXXXXXXX----XXXXXXXXXXX--------------------XXXXX--
-XXX---XXXXXXXXX-XXXXXXXX-XXXXXXXX--XXX------------XXXX--RD-
-----SLENTLTETEGRYSSQLSQMQCMITNVEA--------------------------
QLADIRSDLERQNLEYKVLLDVK---ARLECEINTYRGLLESED---C------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYSCGL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLNN---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--VCASYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLASDDFRT---KY-ET
EVSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLEHTLTESEARYSSQLSQVQRLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACEKSTGPCISNPC----------------------------
-----------------GLR-A-QCRP----------------CN--------TFGY---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PA-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGSC
NWFC---EGSFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENC--ELERRIQ-ERNQQQ
EPL--LCPSYQSYFRTIEELQQK--ILCNKAENARLVVEVDNAKLATDDFRT---KY-ET
ELSLRHLVESDIN-------------------GLRRILDELTLCR--ADLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------SVDLNRVLN
EVRSTYEAV----VETNR----REVEEWYTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLNENEARYGSQLSQVQGLIGSVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CR---------LP
CNTCTTS----------NACDKLTGPCVA---------------------------N---
---P------------CITR-P-RCGP----------------CG--------PFGH---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSACCV-TNNLQASLKSCP--
------------------------RPASICSSSVNC-RPELCLGYVCQPMACLPSVCMPT
TFRPASCLSKT--------------YLSSSR-----L---AAS--------GISSSTGPG
SWYR---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TLQFLNE---
-------------------------RLASY-LT-RVRQLEQENA--ELESRIQ-EASHSQ
VLT--MTPDYQSHFRTIEELQQK--ILCTKAENARMVVNIDNAKLAADDFRA---KY-EA
ELAMRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVGSLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRVLE
EMRCQYETM----VEANR----RDVEEWFNMQM--------------------EELNQQ-
-VAT---SSEQLQNYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLTESEARYSSQLAQMQYMITNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLESEINTYRSLLESED---S---------KLP
CNPCSTP----------SCTPCVPS-----------------------------------
---------PCVPRTVCVPR--IVGVPCSPCPQ-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKAGFSSG-SLKSPGGA
-------------------GGACSRVSTMY-SSSSC-QLPSLSRGSRSFSAC--------
--------SAG--------------LGRSSYRVASCL---PALCLPA-GGFATSYSV-GG
GWFG---EGILTGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1068)

EKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIR-EWCDKQ
VPY--MCPDYQSYFRTIEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-EM
EVSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIVELRR-TVNALEIE--LQA------------QHSM--RD-
-----ALESTLVETEGRYGTQLSQVQCMITSVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
CNPCAPD----------SSPSKSCLPCLPAA-----------------------------
------SCGPSAIRTTCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGCTT-TNSPS---------------
------------------------------------------TPCQNCSRITNVSTIS-S
-N------------NRCHP-G--G------LKVKNY-QPAGHTLRTTLDQGCQPTPCF--
------CRKPI--------------YLTNN-----FI----V-----------RSSLDDC
SWYG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVQMLEQENA--ELESKIQ-EENNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVLQIDNTKLTADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLKQILNVLTLGK--ADLEAQVQSLKEE
-LLCLKNNHKEEINSLQC--QLGERL--HIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCQYESI----METNR----KDVEQWFNTQI--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEVE--LQA------------QHRM--RD-
-----SQECILMETEARYTALLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEITTYRSLLESLD---G------K---RP
CYPCATK----------CEPSP-WTSYKSGAM------------------------ECTA
P--ACTS---------SAP--CGLKEHCSACGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------

PF00038 // ENSGT00900000140814_1_Domain_1 (731, 1069)

QEVTSSKC--QIGERL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLI
ETRCQFEAL----VETNR----RDVEEWFVKQT--------------------EELNQQ-
-VVT---SSEQLQCCQ-SEIIELRR-TVNALEVE--LQA------------QHNL--RN-
-----SLENTLTETEARYSSQLAQVQCMITSVED--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLECEIATYRNLLESED---CK-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSTG-SLKSPGGA
-------------------AGGSTRVATVY-SSSSC-KLP---HGLHSFSVC--------
--------PAG--------------LGRSSFGAAGCL---PVPCLPV-GGFATSYGMAG-
GWFG---EGVLTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLERENS--ELERRIR-EWCEQQ
VPY--MCPDYQSYFRTIEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----REAEDWFDSQT--------------------EELNQQ-
-VVS---SSEQLQNCQ-VDIIELRR-TVNALEIK--LQA------------QHSM--RD-
-----ALESTLVETEARYGSQLSQMQGLIGNVEA--------------------------
KLAEIRADLERQNQEY-----VR---ARLECEISTYRGLLESED---C---------KLP
CNPCGPD----------HVPSKSCLPCLPPA-----------------------------
------SCSPGTVRTTCSPR-----PVCVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------ASNGSQVRGPPEPCARDP---
----------------------------------GC-NST--------STCPPEATRLPS
AGPVSGCQALS--------------FLPRTRLSPGCL---APCYLAA-SG-DSPCVVEHG
AWCE---DGAFSS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRSLEETNA--ELEGKIA-GQCEPG
ALF--VSPDYQCYFDSIEELQQK--ILCTKAENSRLAVQLDNCKLAADDFRS---KY-DA
ELSLRQLVENDIS-------------------GLRGILGELTLCR--SNLEAHVEGLKED
-LLCLKQSHQEEVGVLHG--QLGDRL--NVELDMAP------------------------
---------------------------------------------------TVDLNGALE
EMRCQYETV----LADNR----KEAEEWFAAQA--------------------EELSQQ-
-QLS---SAKQLQCCQ-TEILELKR-RASALEIE--LQA------------QQNL--TD-
-----SLECTMAETEAQYSTELAQMQGLIDSVEA--------------------------
QLAEIRCDLERQNQEYEVLLDTK---ARLEGEIDTYRGLLDSED---SR---------LA
SDPCSA-----------A-------SASSTT-----------------------------
-------CEPSPAYLLCTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MEP--------------ESGFETSSSSAPSS---------IMPYNCL----PN-----
----LSC-RSS--------------SSSRPCVPSSCQ----GITLPG-AC-NIPATVSSG
NWFC---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELERQIQ-ERSQQQ
EPL--VCPNYQSYFRTIEELQQK--ILSGKSENARLVVQIDNAKLAADDFRT---KY-QT
ELGLRQLVESDIN-------------------SLRRTLDELTLCK--ADLEAQVESLKEE
-LLCLKQNHEQEVNSLRS--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------TVDLNSVLS
ETRSQYEAL----VETNR----RDVEEWFARQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEVE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLAQVQGLIGNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
SNPCATT----------NAH---------SS--------------------------C-T
P--CG-------------PR-T-CFKS----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LSNMTSLKSCP--
------------------------RPSSVCSSSMSC-RPEVYLGYVCQPMAYFPSACMPT
TYRAASCLPKT--------------YLSSS-----CR---PAS--------GISSSVGSC
GWLC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENT--SLESKIQ-EACQAQ
VPT--VCPDYQAYFRTIEEIQQK--VLCTKAENARMLVHIDNAKLAADDFRT---KL-RD
GAVPAQL-VSDIN-------------------SLRRILDELTLCK--ADLEMQVESLKEE
-LLCLKKNHEEEVSALQC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLNRMLE
EMRCQYETV----VETNR----RDVEEWFTTQM--------------------EELNQQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLESMLAETEARYSSQLAQMQCLISSVES--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLEGEINTYRGLLESED---C---------KLP
CNPASTP----------SCPPCMPCP----------------------------------
---------------PCGPH--TVCVPCMPCPP-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDCSSTHCSPESCTTAS---
----------------------------------GC-APA--------SSCSIETACLPG
ACATSRCQTPS--------------FLSRSRGLTGCL---LPCYFTG-NC-DSPCLVGNC
AWCE---DGVFTS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRSLEETNA--ELESRIQ-EQCEQD
IPM--VCPDYQCYFNTIEDLQQK--ILCTKAENSRLAVQLDNCKLATDDFKS---KY-ES
ELSFRQLLEADIS-------------------GLHGILDELTLCK--SDLEAHVESLKED
-LLCLKKNHEEEVNLLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TLDLNRVLD
EMRCQYETV----LANNR----REAEEWFAVQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSSQLAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDMK---ARLEGEINTYRGLLDSED---S---------RLS
CNPCSTT----------CT--------SSNT-----------------------------
-------CEPCSAYVICTV--ENCCL----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNSCL----PS-----
----ISC-RTS--------------CTSRPCLPPSCH---G-CTLPG-AC-NIPANIGTC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWCQQQ
VPY--VCPDYQNYFRIIEELQQK--ILCTKAENTRLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVEADIN-------------------GLRRILDGLTLCK--SDLEAKVESLKEE
-LLCLKQNHEQEVNTLRC--QIGERL--NVEVDAAP------------------------
---------------------------------------------------NVDLNRVLN
ETRCQYETV----VENNR----RDVEEWFTTQT--------------------EELNKQ-
-VLS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTETEARYSSQLSQVQCMITNVEH--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEISTYRGLLESED---CK---------LP
CNPCATT----------NACGKPIGPCPIS--------------------------N---
---PCVPCT------PCIPR-S-RCGP----------------CN--------SFVH---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SFHRSLSSSSQGPA---LSMSSS
MYRKGS----------AQRLV----AAPSVYGGAGGHGTRISV-SK--SVVSYASDLS--
--SG---GDLFAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKL---------------------------------TMQNLND---
-------------------------RLASY-LE-KVRSLEQSNS--RLEVQIK-QWYETN
APS--TIRDYSPYYAQIKELQNQ--IKDAQIQNARCVLQIDNAKLAAEDFRL---KF-ET
ERGMRITVETDLQ-------------------GLSKVYDDLTLLK--TDLEVQIEELSKD
-LALLKKEHQEEVDVLRR--QLGNNV--NVEVDAAP------------------------
---------------------------------------------------GLNLGEIMN
EMRQKYEIL----AQKNL----QEAKEQFERQS--------------------EALQQQ-
-VTV---NTEELKGAE-IQVTELRR-TYQNLEIE--LQS------------HLSM--KE-
-----SLERTLEETKARYASQLAAIQGMLSSLEA--------------------------
QLMQIRSDTERQNQEHNILLDIK---TRLEQEIATYRRLLEGED---IG---------T-
------TE---------YQLCT--------------------------------------
-----------------------------LESR--DIKKTRKIKT----------VV--E
EVVDGKVVSSEIKEV-EESV--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------PANVGNC
GWLC---EDSF

PF00038 // ENSGT00900000140814_1_Domain_1 (492, 985)

NGNE-----------------------------------EMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESHIR-EWCQQQ
VPY--ACPDYQSYFRTIEELQQK--ILCSKSENARLVVQIDNAKLATDDFRT---KY-ES
ELSLRQLVEADIN-------------------SLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKQTHEQEVNTLRS--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----RDVEEWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLNESEARYSSQLAQL-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LVC----------
------------------------------------------------TMAPGARNV---
--S--VSA----IDVGCQPGAE-ASVAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHN-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---KNTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADQC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----LETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQ----------AQHTL----KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------ASC--------------------------------------T-
---SCPSC---------GP--VTGGSSSG-HGASMGR-----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGCTT-TNSPS---------------
------------------------------------------TPCQNCSRITNVNTIS-S
-N------------NGCHP-G--G------LTVNNC-QPAGHVLRIPWDQGCQPTPRF--
------CRKPV--------------YLMNN-----FN----A-----------RFSLDDC
SWYG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKE---------------------------------TMHILNE---
-------------------------RLANY-LQ-KVRMLERENA--ELESKIQ-EESNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVLQIDNTKLTADDLRA---KY-EA
EVSLRQLVESDAN-------------------GLKQILNVLTLGK--ADLEAQVQSLKEE
-LLCLKNNHKEEINSLQC--QLGERL--DIEVTAAP------------------------
---------------------------------------------------SADLNQVLQ
EMRCQYESI----METNR----KDVEQWFNTQI--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-SVNTLEVE--LQA------------QHRM--RD-
-----SQERILTETEARYTALLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEITTYRSLLESSD---G------K---RP
CYPRATK----------CEPSP-WTSCKSGAI------------------------ESTA
P--ACTS---------SSP--CSLKEHRSACGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------ASDGSPGCCSSEPCAEAS---
----------------------------------GC-VAA--------SPCPTDTTCLPS
TCATSRCQTPS--------------FLCRTHL--------SPCYFAG-GC-NSPCLVGSC
AWCE---EGAFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-RVRSLEENNA--ELECRIR-EQCEPD
APL--VCPDYQRYFDTIEELQQK--ILCTKAENSRLAVQVDNCKLAADDFRS---KY-ES
ELSLRQLVENDIS-------------------GLRGILGELTLCK--SDLEAHVESLKDD
-LICLKKGHEEEVNLLRE--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TVDLNKVLD
EMRCQYERV----LANNR----RDAEEWFTAQT--------------------EELNQQ-
-QMS---SAQQLQGCQ-TEMLELKR-TANALEIE--LQA------------QQTL--TE-
-----SLECTVAETEAQYSTQLTQMQCLIDSVEH--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRGLLEKED---S---------RLP
CNPCSTV----------PT--------SNST-----------------------------
-------CEPCSAYVICTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------LDTKGCTT-TMSSA---------------
------------------------------------------TPCQSCSGITNLTTIL-P
-N------------TSCQHGG---------LKANSC-QPTGHDLRTLQSQDDEPTPCF--
------SLTPL--------------CLISN-----FH----T-----------CPFLDDC
GWCD---GSI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKE---------------------------------TMKILNN---
-------------------------RLTKY-LE-KVRMLERENA--ALECKIQ-EECNKE
LPV--ICPDYLSYYATIEELQQK--ILCTKAENSRLVSQIDNTKLTADDVRA---KY-EA
EVSLRQLVEADAN-------------------GLQQILNALTLGK--ADLEAQVQSLKEE
-LLCLKNDHEQEISSLQS--QLGDRL--NIEVTSAP------------------------
---------------------------------------------------SVDLNRVLR
EMRCQYESI----METNR----KDVEEWFNTQM--------------------EELNQQ-
-VVT---STQQQQCYQ-KEIIELRR-TMNALEIE--LHA------------QHRM--RD-
-----SQECALTETEARYAALLTQIQCLIDNLEA--------------------------
QLAEIRGALERQNREYEILLDVK---SRLECEIATYHSLLESSD---G------K---LP
CHPCAIK----------HEPSA-CISSKARTM------------------------ECTA
P--VHTS-S-------LGP--CGIHESRSACSI--LPRILVKICT----------IT--E
EIKDGKVISSHKHVQ--------PCFITRTAKA-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSFNFCL----PN-----
----LSF-RSS--------------CSSRPCVPPSCC---G-TTLPG-AC-NIPANVGSC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIL-ERSQQQ
EPL--VCPNYQSYFRTIEELQQK--ILCAKSENARLVVQIDNAKLAADDFRT---KY-ET
ELGLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LICLKSNHEEEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRAQYEAL----VETNR----RDVEEWYIRQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-TEIIELRR-TVNALEVE--LQA------------QHNL--RD-
-----SLENTLTETEARYSCQLNQVQSLISNVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEINTYRGLLDSED---CK---------LP
CNPCATT----------NAYGKTITPCIS---------------------------S---
---PC---APAAPCTPCVPR-S-RCGP----------------CS--------SYVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MLYAKPPPTIK------------------------
---------------------EVTCSPITCPST---------MSLTCCQ----PS-----
----FSC-RTS--------------CSSRPCVAPSCH----SCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRRLERENA--ELESLIQ-QRCQEQ
DPL--VCANYQSYFRTIEELQQK--ILCAKSENARIVTKVDNAKLASDDFRT---KY-ET
ELSLRQLVESDIN-------------------SLRRVLDELTLCR--SDLEAQVESLREE
-LLCLKKNHEEEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNQVLN
ETRSQYEAL----VETNR----REVEEWFTRQT--------------------EELSKQ-
-VVS---SSEQLQSCQ-AEIIELRR-MVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCMITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRALLDGED---CK---------LP
CNPCATT----------NASGNPCGPCGCSQK----------------------------
---CGCN-----------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICSPIFSSGSV-RGLCGT
-------------------AGGISRVSSVH-SVGSC-RVPSLAGAA----------RSAS
SVRL------------------------GLSGLGSCL---PGSYLST-GC-YPSGFAGSG
TWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWYESQ
IPY--ICPDYQSYFKTIEDLQQK--ILLTKAENARLVLQIDNAKLAADDFRT---KY-ET
ELGLRQLVEADTN-------------------GLRRILDELTLCK--ADLEMQVESLKEE
-LVCLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLTKILD
DMRCQYEAL----VENNR----RDVESWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQMQGLISNVEA--------------------------
QLAEIRCDLERQNHEYQVLLDVK---ARLESEIATYRRLLESED---C---------KLP
AHPCATE----------CKPAVRVPYIST-------------------------------
--------GP-----------------CAPGSQ-----VSAQIRT----------IT--E
EIRDGKIISSREHMQ--------PCPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------DVGVHYGPE-GDTAPLCLSATVAHANRVRVGS---TPLGRPSLCLPQ
SCRT-AC------------------------------------ALPG-TC-HIPGNVGIC
GAYG---EVTLNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

HEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELETTIR-ETSKCH
ETS--VCPDYQSYFRTIEELQQ--KILCTKAENARIVIQIDNAKLAADDFRI---XX-XX
XXXXXXXXXXXXX-------------------XXXXXXXXXXXXX--XXXXXXXXXXXXX
-XXXXXXXXXXEVNTLRC--QLGDKL--RIELDTQP------------------------
---------------------------------------------------TIDLSRVLE
EMRCQYEAM----VETNR----QDVEQWFQAQS--------------------EGINLQ-
-AMS---CSEELQCCQ-SEILELRC-KVNALEVE--REA------------QHNL--KD-
-----CLQNSLCEAEARFGTELAQMQILISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLESEINTYRRLLESED---C------K---LP
CNPCSTP----------PTYVA----PA-----------------------------ST-
---PRPSC---------VP--RVPCGSGSVCGVSTSGRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSFYSTS-SCP----LGC----------
------------------------------------------------TMAPGARNV---
--F--VSP----IDVGCQPVAE-ANAASMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TSHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---KNTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMKFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELETTLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLHQLVEADKC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKF--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----VETNH----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQ----------AQHTL----KD-
-----CLQNSLCEAEDRYGTELAQMQSLISNLEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------ASC--------------------------------------T-
---SCPSC---------GP--VTGGSPSG-HGASMGR-----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGHTT-TNSPS---------------
------------------------------------------TPCQSCSRITNVSNIS-S
-N------------NSCQC-G--G------LKVNNR-QPAGHVQRIFQDQGCRPTSCS--
------CRMPI--------------YLVNN-----FN----A-----------RSSLDDC
SWYS---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNN---
-------------------------RLANY-ME-KVRMLERENA--ELESKIQ-EESNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLKQILNVLTLGK--ADLEVQVQSLKEE
-LLCLKNNHKEEINSLQC--QLGERL--HIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCHYESI----METNR----KDAEQWFNTQM--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEVD--LQA------------QHRM--RD-
-----SQECILTETEARYTALLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDIK---SRLECEITTYRSLLESLD---G------K---LP
CYPCATK----------CEPSP-WTSCKSRAM------------------------ECTA
P--ACTS---------SAS--CGLQEPCSACGP--LSRILVKIFT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFTGR-----------------SLHRSVSSSSRGPA---LSVSSS
MYRLGG----------TQHLQ----VAPSVYGGAGGHGTRIST-SR--RVVSYGGDLS--
---G---GDLLVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKM---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRSLEQSNL--HLEVQIR-QWNETN
APS--ASRDYSAYYKQIEALRNQ--IKDAQLKNARCVLQIDNAKLAAEDFRL---KY-ET
ERGIRLTVEADLQ-------------------GLHRVLDDLTLRK--TDLEIQIEELKKD
-LILLQKEHQEEVNSLRR--QLGNTV--SVEVDAAP------------------------
---------------------------------------------------GLNLSAIMD
EMRQKYEAM----AQENL----RKAKEQFELQI--------------------ETLHQE-
-VIL---SSKELKENE-GRIKELRR-TYQNLEID--LQS------------YLSK--KD-
-----SLERTLAETKARYADQLATIQALLSTLEF--------------------------
QLMQIRTDAERQNNDYSILLDIK---TRLEQEIATYRRLLEGED---VM---------G-
-------S---------YILCL--------------------------------------
-----------------------------NLNS--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EENM--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDCSSTHCSPESCTTAS---
----------------------------------GC-APA--------SSCSMETACLPG
ACATSRCQTPS--------------FLSRSRGLTGCL---LPCYFTG-SC-NSPCLVGNC
AWCE---DGVFTS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRSLEETNA--ELESRIQ-EQCEQD
TPM--VCPDYQHYFNTIEDLQQK--ILCTKAENSRLAVQLDNCKLATDDFKS---KY-ES
ELSLRQLLEADIS-------------------SLHGILDELTLCK--SDLEAHVESLKED
-LLCLKKNHEEEVNLLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TLDLNRVLD
EMRCQYETV----LANNR----REAEEWFAVQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSCQLAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLEGEINTYWGLLDSED---S---------RLS
CNPCSTT----------CT--------SSNT-----------------------------
-------CEPCSAYVICTV--ENCCL----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCYL----PN-----
----LSF-RSS--------------CSSRPCVAPSCH---S-APLPG-AW-NIPANVGNC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLNE---
-------------------------RLASY-LE-KVRQLERENA--ELESRIQ-ERCQQQ
EPL--MCPSYQSYFRTIEEFQQK--ILCAKSENARLVVQIDNAKLAADDFRT---KY-ET
ELGLRQLVESDMN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKRNHEEEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAM----VETNR----RDVEEWYTNQT--------------------QELNKQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLSQVQCMITNVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACSKP-------------------------------------
----IGPC-VSNPCTPCVPR-P-RCGP----------------CS--------PFVH---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------IMASQLCSPIFSSGSL-RGHCGT
-------------------TSGISRVSCVR-SVGSC-RGPSLAGVS----------GSAS
SIRL------------------------GLSSLGSCL---PGSFLSS-GL-HSSGFAGAG
GWLC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-EWYESQ
VPY--ICPDYQSYFKTIEELQQK--ILLTKADNARLVLQIDNAKLAADDFRT---KY-ET
ELGVRQLVEADTN-------------------GLRRILDELTLCK--ADLEMQVESLKEE
-LICLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
EMRCQYETL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-NVNALEIE--LQA------------EHSM--RN-
-----SLECTLAETEARYSSQLAQMQGLIGNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLESEIATYRRLLEGED---C---------KLP
AHPCATE----------CKPAVRVSYVSS-------------------------------
--------GS-----------------CAPAPQ-----LSTQIRT----------IT--E
EIRDGKIISSREHVQ--------PL---------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---S-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKSNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----REVEQWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CN---------LP
SNPCATT----------NACSKPIGPCLSNPC------------------------T---
------SCVPPAPCTPCAPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSEASHTHCSSESCARAS---
----------------------------------GC-APA--------SAHSLERTCLPS
DGSAGRCRSPG--------------FLSRSCLSTRCL---TPCYLVG-SC-DSPCLAGSC
AWCE---DGMLNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQLLND---
-------------------------RLASY-LE-KVRSLEETNA--ELECKIR-EQCQES
IPL--PCPDCQCYFNIIEDLQQK--ILCTKAENSRLAVQLDNCKLAAEDFRT---KY-DS
ELSLRQLVENDIS-------------------GLRGILGELTLCK--SDLEAQVESLKDD
-LLCLKKSHKEEVNLLHG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TIDLNEVLD
EMRCQYETL----LANNR----RDVEEWFAAQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEMLELKR-TANTLEIE--LQA------------QQSL--IE-
-----SLECTVAETEAQYGTQLAQMQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDTK---ARLESEISTYRGLLDSED---C---------RLS
CNPCSTA----------CT--------SNST-----------------------------
-------CEPCSAYVLCTI--ENCHL----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSSG-SLKVPGGA
-------------------GGGSARVSTIF-SSSSC-KLSGLSRGPRSFSAC--------
--------SVG--------------LGKSSCRAASCL---PALCLPS-GGFATSYGM-AG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIRPDWCEQQ
VPY--LCPDYQSYFQTIEELQKK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-ET
EVTMRQLVESDMN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLN
EMRCQYETL----VENNR----REAEDWFNTQT--------------------EELNQQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQMQGLIGNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEISTYRGLLDSED---C---------KLP
CNPCAPD----------HSPSKSCLPCLPAA-----------------------------
------SCGPGTAHTTCSPR-----PICVSCPG-----SRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-YTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
EQSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQMESLKEE
-LLSLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRNQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RY-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACEKPIGSCVTNPC----------------------------
-----------------GPR-S-RCGP----------------CN--------TFGY---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSDR-----------------SFQRSLSSSSETTA---IS----
---IGG----------NQHLR----VVLSVYGGYGGHGTRISN-SR--HWVNC-------
--GN---GDLLFG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKT---------------------------------TMQNLND---
-------------------------RLASH-LE-KVRTLEPFNS--KLELKIK-RWYEKD
APS--TNRDYSAYYRQIEEPKNQ--IKEAQQE-KACVLKVDN--IAAEDFRL---KY-ET
EGGMHLAMEADLQ-------------------GS-NVFDDLTLYK--TDLEIQIEQLNKE
-LVILKKEHQEEVDGLHK--QLGNTV--NVQLNAVP------------------------
---------------------------------------------------GQSLSAIMD
EMRQKYEAL----AQENL----QKAKEQFKIQT--------------------ETLQQQ-
-VTV---NVADLKDSE-IQLKKLSR-TYQNLSLN--LKS------------HLSM--KD-
-----SLEHTLQDTKAHYHRQLAAVQELLNTLKA--------------------------
QMMQVRIDAER-NKEFEALLDIK---TRLEQETATYRHLLEAED---MS---------T-
------TE---------YQISI--------------------------------------
-----------------------------LEDR--EIKKTRKIKT----------VM--Q
EVVDGKVVTSEIKDM-ESV---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MLCDELIPTS
WGIKGP-RRQRPHSDHCTNP---STAL-LTTMPYNCCLP-SISCH----T----------
-------SC---------------------------------------------------
-------------------S------SRPCL---PP-SCHSCTL---P-----------G
-----AC---------------------------------------N-I----PANVGTC
GWSC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEGRIQ-EWCQQQ
VPY--VCPNYQSYFRTIEELQQK--ILCSKSENNRLVVLIDNAKLASDDFRT---KY-ET
ELSLRQLVEADIN-------------------SLRRILDNLTLCK--SDLEAQVESLREE
-LLCLKKNHEEXXXXXXX--XXX--X--XX-XXXXX------------------------
---------------------------------------------------XXXXXXXXX
XXXXXXXXXXXXXXXXXX----XXXXXXXXXXX--------------------XXXXX--
-XXX---XXXXXXXXX-XXXXXXXX-XXXXXXXX--XXX------------XXXX--KN-
-----SLENTLTESEARYSSQLSQLQCMVTNVES--------------------------
QLAEIRGDLDRQNQEYQVLLDVK---SRLECEISTYRNLLECED---H------K---LP
CNPCATT----------NACGNS------------------------------------C
GSCVKSCSRTC-------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------LAVSH-----------------RFHRSLSSSSQGSP---LS----
---TIG----------MQHLQ----PAFSVYGGAGGHGTRIST-PR--GIANSWNELT--
---G---DNLFFG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKA---------------------------------LLQSLNG---
-------------------------RLASY-LD-KVQALEMSNS--KLEAQIK-QWYETN
LPR--IDGDYSTHYKQIEELQKQ--XXXXXXXXXXXXXXXXXXXXXXXXXXX---XX-XX
XXXXXXXXXXXXX-------------------XXXXXXXXXXXXX--XDLESQIEDLTGD
-SLLLKKEHEEEVNRLHE--RLGKNV--SVELDAAP------------------------
---------------------------------------------------GLSLRTIMN
EMRQKYEDM----VQKNL----QEVKEQFEKQT--------------------KALQQQ-
-VAV---NTEEMKGRE-VQVNELKL-TYQSLKTE--LQS------------HLSM--KK-
-----ALKNTLEETKAQYHAKLASIWELLSSLEA--------------------------
KLMKIRKEAEHQRDECNTLLDIK---TRLEQEIATYRHLLKGKD---VK---------G-
-----------------LQLST--------------------------------------
-----------------------------PKER--EVKKMRKIKA----------IV--K
EVVNDKVVSSTVFEKMEEEI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFNQR-----------------RFHRSLSSSSQGPA---LSMSSS
IYRRG--------------------VAPSVYGGAGGHGTRIST-SR--HMLNYGSDPA--
---G---GNLFAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKM---------------------------------TMQNLND---
-------------------------RLASY-LE-RVRSLEQSNS--HLELQIK-HWYETN
TPS--TSRDHSAYLEQIKELRDQ--IKDAQLQNARCVLQIDNAKLAIEDFRL---KY-EA
EQGICQTVVADIH-------------------GLKMVFDDLTLKK--ADLEIQIEELTKD
-LHLLQKEHEEEVRSLRA--HLGNNV--NVEVDAAP------------------------
---------------------------------------------------SLNLGAIMN
EMRQKYDAM----AQENL----QKAKEQFEIQI--------------------NDLQKQ-
-VTV---STEELKGNK-DQIKEQRH-THQVLEIE--LQS------------LLSM--KE-
-----ALEHTLQETNARYSSHLATIQAQLNLLEG--------------------------
QLVQVRMDTERQIHEYNILLDIK---IRLEQEIATYRRLLEGED---VK---------KT
--KNKTRE---------YQLST--------------------------------------
-----------------------------LDER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EENI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYSCCL----PS-----
----LSC-RTS--------------CASRPCVPPSCH---G-CTLPG-AC-NIPANVSSC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELECRIR-ERCQPQ
EPL--VCANYQSYFRTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-ET
EMSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKSNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VDTNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQCMISNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CN---------LP
SNPCATT----------NACGKPIGPCVSNPC------------------------T---
---PCTPCAPPVPCTPCVPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSGGSPVCSPSESCAGDP---
----------------------------------GC-D----------------AARLPS
AGPVPGCQAPS--------------FLPRAHLPLGCL---APCYLSG-SC-DGPCLVESG
VWCE---DGAFNCH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1069)

EKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRSLEETNA--ELESKIQ-GQWELD
ALF--VCPDCQRYFHTIEELQQK--ILCTKAENSRLAVQLDNCKLAAADFRS---KY-DS
ELSLRQLVENDIS-------------------GLRGILGELSLCR--SGLEAHVESLKEE
-LLCLKKSHQEEVSVLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TVDLNGALE
EMRCRYETV----LANNR----REAEKWFSAQA--------------------EELNQQ-
-QLS---SVEQLQGCQ-TEILELKR-SANTLEIE--LQA------------QQNL--TE-
-----SLECTVAETEAQYSTQLAQMQGLIDNVET--------------------------
QLAEIRCDLERQNQEYQVLLDTK---AQLESEISTYQGLLDSED---SR---------LT
SNPCSI-----------M-------PASSST-----------------------------
-------CEPVSAFVLCTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSCESCL----PT-----
----MSC-RTS--------------CSSRPCIPNSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEARIQ-ERNQQQ
DPL--VCPAYQSYFATIEQLQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLGEIRADLERQNQEYQVLLDIR---ARLECEINTYRGLLESED---CK---------LP
CNPCATS----------NACGKPIGPCVSNPC------------------------T---
------PCPPPAPCTPCVPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MT---
--S--DHC----SSLLSEQVSE-ANAASLCLLANVAYANRVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYS---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERDNA--ELETKLR-ERSKCH
EST--VCPDYQSYFCTIQELQQ--KILCTKSENNRLVVQIDNAKLAADDFRT---KY-ET
ERSLHQLVEADIC-------------------GLRRVLDNLTLAK--CDLEAQLESLKEE
-LLCLKKNHEQEARTLRG--QLGDKL--RIELDIEP------------------------
---------------------------------------------------TIDLSRVLG
EMRGQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRR-SVNALEVE--LQA------------QHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLINNVEE--------------------------
QLSEIRADMERQNQEYQVLLDVK---VRLENEIATYRNLLESED---C------K---FP
CNPCATP----------AFS------TP-----------------------------SP-
---APAACAPC---SR------ATHGLCSSIGY---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSMGSV-KGLCGA
-------------------AGGISRVSSIR-SVGSC-RVPSLAGAA----------GCIS
SVRS------------------------GLTSLGSCL---PGSYLSA-GC-HPSGFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWYESQ
IPY--TCPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVGALRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRILE
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VLS---SSEQLQCCQ-SEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRRLLEGED---C---------KLP
PPPCAMA----------CKPAIRVPSVPP-------------------------------
--------APCAPA-----------VACIPAPQ-----AGTQIRT----------IT--E
EIRDGRVISSREHLQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SFHRSSSSS--------SQISGP
VVRKGT----------MQNI-----YAPSVYGGAGGQGIRISST-S--YVTNSRGGL---
---S---GDFSVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKI---------------------------------TMQNLND---
-------------------------RLASY-LE-KVRSLEQSNS--HLEIQIR-QWYEKN
SPT--LSRDYSAYFKTIEDLQNK--IKDARLANAHCVLQLDNSKLAAEDFRI---KY-ET
EHGMRLSVEADLQ-------------------GLHKVFDDLTLQK--TDLEIQIESLTEE
-LAFLKKAQEEDIANLRG--QLGKTV--NVEVDAAP------------------------
---------------------------------------------------GHDLATIMN
EVRQKYELM----AQKNL----QEAKEQFEKRT--------------------KDLQVE-
-VRL---SIDEIKTYE-PQVTELRR-NYQNVKID--LQA------------QYSM--KE-
-----SLERALEETEARYGSRLAQIQALISAIEA--------------------------
QLIQVRSDTERQNEEYNVLLDIK---TRLEMEIATYRRLLEGED---VX---------X-
------XX---------XXX-X--------------------------------------
-----------------------------XXXX--XVKKIRKIKT----------VV--E
EVVDGKVVSSQVRIE-ESV---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSGGSPVCSPSESCAGDP---
----------------------------------GC-D----------------AARLPS
AGPVPGCQAPS--------------FLPRAHLPLGCL---APCYLSG-SC-DGPCLVESG
VWCE---DGAFNCH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1069)

EKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRSLEETNA--ELESKIQ-GQWELD
ALF--VCPDCQRYFHTIEELQQK--ILCTKAENSRLAVQLDNCKLAAADFRS---KY-DS
ELSLRQLVENDIS-------------------GLRGILGELSLCR--SGLEAHVESLKEE
-LLCLKKSHQEEVSVLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TVDLNGALE
EMRCRYETV----LANNR----REAEKWFSAQA--------------------EELNQQ-
-QLS---SVEQLQGCQ-TEILELKR-SANTLEIE--LQA------------QQNL--TE-
-----SLECTVAETEAQYSTQLAQMQGLIDNVET--------------------------
QLAEIRCDLERQNQEYQVLLDTK---AQLESEISTYQGLLDSED---SR---------LT
SNPCSI-----------M-------PASSST-----------------------------
-------CEPVSAFVLCTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQVCSPVFSSGSV-KGLCGT
-------------------AGGISRVSSVR-SVGSC-RVPGLAGAV----------GSAS
SIRL------------------------GLSGLGSRL---PGSYLAA-GC-YPSGFVGSG
GWFC---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELETRIR-EWYESQ
IPY--ICPDYQSYFKTIEDLQQK--ILLTKAENARLVLQIDNAKLAADDFRT---KY-ET
ELSMRQLVEADTN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VMS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQMQCMITNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLESEIATYRRLLEGED---C---------KLP
AHPCATE----------CKPSVRAPYVST-------------------------------
--------VPCAPA-----------VPCGPAPQ-----VSTQIRT----------IT--E
EIRDGKVVSSREHLQ--------PCPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------IL

PF00038 // ENSGT00900000140814_1_Domain_1 (628, 1069)

CSKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVEADIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VDTNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQNYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLSEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVTNPC----------------------------
-----------------ITR-S-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MAAPS-THTCGSLKGP----------
-------CR------------------------------VSTVSRPNSAASATCRPG---
--------------NIFPRR------SSICL-PSLG-QPTPSLPNSCRSGGFMPSTCLPP
PSLGSTCVPPP--------------CIL--------------------P--SARPLQCFP
RGPE---EGILNC

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMEFLNN---
-------------------------RLGNY-LE-RVRCLEQENA--ELEAKIR-EWYEHE
NAY--VCTDFKPFYCTIDELQQQ--ICCTKADNAKLCLDIDNLKMASDDYCT---KY-DY
ELSLRQRDECDSS-------------------GLRKVLDNLTLCR--ADLEAQLESLTEE
-MMCLKKNHEEESSALRS--QLGDRI--NVEVDAAP------------------------
---------------------------------------------------SCNLNKVLD
EMRCQYEAD----LEKNR----REVEDWYCAQM--------------------EELNKE-
-VIS---SGEQLQCCQ-TEIIETRR-CVQTLEIE--LQA------------QQSM--KS-
-----ALETTLQETESRYCTQLAQLQCLISNVEA--------------------------
QLTEIRSDIERQNCDYKALLDEK---ARLDCEIAAYRNMLEGED---C------KIPNRP
CDPEGSTTVRSTVCRQVCKPEPICVPICPPDCKPPGPMVGPKLTPSCANPSGPVFATCGP
PPCAP---PPCGPRGPCGPRSPVCPQPCGPCPP--GPRINTKICR----------M----
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESLIQ-ERCQPQ
EPL--LCPSYQSYFRTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEEEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCMISNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACSKPIGPCVSNPC------------------------V---
------PCAPPTSCTPCTPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTNGCT--TVSSS---------------
------------------------------------------TPLQSCSRITNFRTIF-S
-N------------KGCQGGG---------LEANSC-Q---------------AIPCF--
------CPMPI--------------CLSGN-----FS----A-----------CLPPNDC
GWCG---EGF-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMQILND---
-------------------------RLANY-LE-KVQMLERENA--DLECKIQ-GECNKE
VPV--ECPDYLSYYTTTEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---KY-EA
EVSVRQLVEADAK-------------------GLQQILNALTLGK--ADLEARVESLKGE
-LLCLKNNHKQEINSLQS--QLGDRF--NIEVTTAP------------------------
---------------------------------------------------SVDLNRVLQ
EMRCQYESI----VETNR----RDVEQWFNMQM--------------------EELNQQ-
-VVT---SSQQQLCYQ-KEIIELRC-TMNTLEIE--LQA------------QQRM--RE-
-----SQECILAETEARYTALLAQIQCLIDGLEA--------------------------
QLAEIQCALERQNQEYEVLLNVK---SRLECEIATYRSLLESSD---G------K---FP
CNPRATK----------CNSSC-E----TKAM------------------------ECTA
P--VYTSCSQC---AALAP--RGICEPCNTCRP--LPRILVKICT----------IT--K
EIKDGKVISSHEHVQ--------PCYITRPAKG-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTQGCTM-TVS-----------------
-----------------------------------------STPSQNCSGITNLRTISSH
--------------HVCHHS-----------------N----------------------
-------AERIPQ--------------DQRCQPVPCL-RHIPIYLM--SNFNGRASLDDY
SWCS---EG-INSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1064)

ERE---------------------------------TMQILND---
-------------------------RLASY-LE-KVRMLEQENA--ELEGKIQ-EEGNKE
LPI--LCPNYLSYYATIEELQQK--ILCTKAENSRLVSQIDNTKLAADDMRA---NY-EA
EVSLRQLVEADAK-------------------AVQQILGVLTLNK--ADLEARVQSLKEE
-LLCLKNSHQEDISSLQC--QLGDRL--NIEVTAAP------------------------
---------------------------------------------------SVDLNQILQ
EMRCRYESI----IETNR----RDIEQWFNAQV--------------------GKVEKS-
-KTV---ITLPSQIPA-ISVFQMEE-L------------------------NQQV--RD-
-----SQECIVEETEARYTALLVQIQSLVHHLEA--------------------------
QLAEIRSASERQSQEYEILLDIK---SRLECEIATYRSLLESSD---GK---------FP
CKPCAT-K---------CEPSRT-------------------------------------
---RAVECTAAPVYSSSVP--HGLLQPCRACGP--PSRILVKIHT----------IT--K
EIKDGKVISSHEHVQ--------PCYITRSARA-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SVHRSLSSSSQGPA---LSMSGS
LYRKGG----------VQRLG----AAPSVYGGAGGHGTRISV-SK--TVVSYT------
--SG---GDMFGG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NGKL---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRSLEQSNS--RLEAQIK-QWYETN
APS--TVRDYSPYYAQIKDLQNQ--IKDAQMQNARCVLQIDNAKLAADDFRL---KY-EA
ERGMLVTVEADLQ-------------------GLSKVFDDLTLQK--TDLEIQIEELNKD
-LAILQKEHQEEVDALRR--QLGTNV--NVEVDAAP------------------------
---------------------------------------------------GLNLGEIMN
EMRQKYEVL----AQKNL----QEAKEQFEKQS--------------------AALQQE-
-VTV---NTAELKGTE-LQVTELRR-TCQGLEIE--LQS------------LLSM--KE-
-----SLERTLEETKARYASQLAALQGMLSSLEA--------------------------
QLMQIRSDTERQNQEHNALLDIK---TRLEQEIATYRRLLEGED---VR---------T-
------TE---------YQLAT--------------------------------------
-----------------------------LESK--DIKKTRKIKT----------VV--E
EVVDGKVVSSEIKEV-EERV--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----SN-----
----LSC-RSS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESLIQ-ERCQPQ
EPL--LCPSYQSYFRTIEELQQK--ILCAKSENARLVVQIDNAKLASDDFRT---KY-QT
EQSLRQLVEADIN-------------------SLRRILDELTLCK--SDLEAQVESLREE
-LLSLKKNHEEEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRAQYEAL----VETNR----REVEEWFTTQS--------------------EELNKQ-
-VVS---SSEQLQTHQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCMISNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CNPCATT----------NVSGSSCGPCCSSQK------------------------R---
------------------------C-----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTQGCTA-TISPS---------------
------------------------------------------TPPQNCSGITNFRAAS-S
-N------------NSCHH-------------------------SGPEGQGCCSTPCL--
------CCTPI--------------DLIGS-----FN----G-----------RPCPDSC
VWYW---EGI-NSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1064)

EKE---------------------------------AMQALNG---
-------------------------RLANY-LE-KVQKLEEENA--ALEGRIQ-EECTKE
LPI--LCPDYLSYYTIIEGLQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-ET
EVSVLQLVEADTS-------------------ALQQILDALALGK--ANLEAREQSLKEE
-LLGLKTSHEEEVSLLQC--QFGDRL--NIEVTAAP------------------------
---------------------------------------------------SVDLNQILQ
KLRCQYESL----METNR----KDVEQWFNSQM--------------------EELNQQ-
-VVT---GNLQQQCCQ-AELLELRR-TVNTLEVE--RQA------------QQQM--RD-
-----SQERILGETEARYTALLSQIQSLIHTLEA--------------------------
QLAEIRSALERQNQEYEILLDTK---SQLECEIATYRSLLESSD---G------K---LP
CEPCTTK----------SEPSM-----WARAR------------------------ECPA
L--VYTS---------PAL--TGTRK---TCGP--LPRILVKICT----------IT--M
EVKDGKVISSYEHVQ--------PCYITR-----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSACCV-TSNLQASLKSCP--
------------------------RPASVCSGSVNC-RPELCLGYVYQPMACLPSVCMPT
TFRPSSCISKT--------------YLSSSR-----W---PAS--------GISSTMGPG
GWYS---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LA-RVRELERENA--ELESRIQ-EASHSQ
VLT--MTPDYQSHFRTIEELQQK--ILCTKADNSRMVVNIDNAKLAADDFRA---KY-EA
ELAMRQLVEADIN-------------------GLRRVLDDLTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVGSLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRVLE
EMRCQYETM----VEANR----RDVEEWFNMQM--------------------EELNQQ-
-VAT---SSEQLQNYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLTESEARYSSQLAQMQCMITNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRNLLESED---S---------KLP
CNPCSTP----------SCNPCAPSL----------------------------------
----------CVSRTVCVPR--TVCVPCSPCPP-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-YTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACEKPIGSCVTNLC----------------------------
-----------------GPR-S-RCGP----------------CN--------TFGY---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LGC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDIGCQPGAE-ANVAPMCLLANVAHTNRVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADKC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----LETNR----QDVEQWFQAQS--------------------EGISLQ-
-DMS---CSEELQCCQ-SEILELRC-TVNALEVE--R------------QAQHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---TRLENEIATYRNLLESED---C------K---LP
CNPCSTP----------PSCVT----AP-----------------------------CA-
---PRPSC---------GP--CTTCGPTC-GASTTGSRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLRS------------------------GLSGLGSCL---PGSYLSS-GC-HTSGFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELESRIR-EWYESQ
IPY--ICPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LTCLKKNHEEEVSVLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILE
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQMAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRRLLEGED---C---------KLP
PPPCATA----------CKPAIRVPSVPP-------------------------------
--------VPCAPA-----------VPCTPAPQ-----VGTQIRT----------IT--E
EIRDGKVISSREHVQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKAGFSSG-SLKSPGGA
-------------------SGGSTRVSPMY-SSSSC-KLPSLSRVARSFSAC--------
--------SVG--------------LGRSSYRATSCL---PTLCLPA-GGFATSYSV-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIH-EWCEQQ
VPY--MCPDYQSYFQTIEELQKK--TLCSKAENARLVVEIDNAKLAADDFRT---KY-ET
EVSLRQLLESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQS--------------------EELNQQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEID--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQMQCMITNVEG--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
CNPCAPD----------YSPSKSCLPCLPAA-----------------------------
------SCGPSAARTNCSPR-----PICVSCPG-----GRF-------------------
----------------------------------------------------------

MSYNCCLPNLSCRTSCSSRPCVAPSCHGCTLPGACNIPANVGTCGWLCEGSFNG

PF00038 // ENSGT00900000140814_1_Domain_0 (55, 391)

NEKETM
QFLNDRLASYLEKVRQLERENAELEGRIHEWCQQQVPFVCPDYQSYFRTIEELQQKILCS
KSENARLVVQIDNAKLAADDFRTKYETELSLRQLVEADINSLRRILDELTLCKADLEAQV
ESLKEELLCL---KKNHEEEANSLRSQIGDRLNVEVDAAPTVDLNRVLNETRCQYEAL--
--VETN-RRDVEEWFI-TQTEELNKQVVSSSEQVQSCQA-EIIELRRTVNALEIELQAQH
NLRNSLENTLNETEARYSSQLAQVQCLISSVESQLA----------------EIRGDLER
QNQEYQVLLDVRARLEGEINTYRGLLESED

ENSGT00900000140814_1_Linker_0_1 (391, 494)

CNT---------MPYNCCL----PN-----
----LSC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGSC
GWLC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEGRIH-EWCQQH
VPF--VCPDYQSYFRTIEELQQK--ILCGKSENTRLLVQIDNAKLASDDFRT---KY-EM
ELSLRQLVEADLN-------------------SLRRILDNLTLCK--SDLEAQVESLREE
-LLCLKKNHEEEANSLRS--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----RDVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSSQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLNETEARYSSQLAQLQSLISSVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLEGEINTYRGLLESED---CK---------LP
CNPCATT----------NACGNSCG---PRGC------------------------S---
------------------QQ-R-CC-----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------TDFSRR-----------------SFHRSLSNSLQASV---VS----
---TVG----------MQRLG----MTPSVYGGAGGRGIRISN-SR--HRANYGSNLT--
--GG---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKM---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRTLEQSNS--KLEVQIK-QWCETN
APR--AGPDYSAYYKQIEELRNQ--IKDAQLQNARYVLQIDNAKLAAEDFRL---KY-ET
ERGIRLTVEADFQ-------------------GLNKVFDDLSLHK--TDLEIQIQELNKD
-LALLKKEHREEVDGLYK--HLGNTV--NVEVDAAP------------------------
---------------------------------------------------GLNLGAIMN
EMRQKYEVM----AQKNL----QEAKEQFERQT--------------------AVLQQQ-
-VTV---NTEELKGTE-VELTELRR-TSQSLEID--LQS------------HLSM--KE-
-----SLEHTLEETKARYSSQLANLQSLLSSLEA--------------------------
QLMQIRSDMERQNSEYHILLDIK---TRLEQEIATYRRLLEGED---VR---------T-
------TE---------YQLST--------------------------------------
-----------------------------LEER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EENI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSFYSSS-SCP----LGC----------
------------------------------------------------TMAPGARNA---
--P--VSP----IDVGCQPGAE-ANAASMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHA-AC------------------------------------PLPG-TC-HIPGNIGIC
GASG---KNTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELETTLL-ERSKCH
EST--VCPDYLSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADKC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----LETNH----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQ----------AQHTL----KD-
-----CLQNSLCEAEDRYGTELAQMQSLISNLEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------ASC--------------------------------------T-
---SCPSC---------GP--VTGGSPSG-HGASTGR-----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSNCCVTTTGSPGTGKSCT--
------------------------RAASVCSTGMSC-RPEACMSYVCQPMGYVPSVCLPT
TYRTTSCLSKT--------------YLSSSCRPSSCR---PSCSLPG-SY-GIPCSVGGS
NWYC---DGVFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--NLESKIQ-EACQSQ
MPT--MCPDYQAYFRTIEELQQK--VLCTKAENARMVVQIDNAKLAADDFRT---KY-ET
EVSLRQLVEADIN-------------------GLRRILDEMTLCK--ADLEAQVESLKEE
-LLCLKKNHEDEVNALRC--QLGDRL--NIAVDAAP------------------------
---------------------------------------------------PVDLNRMLE
EMRCQYETV----VENNR----RDVEEWFNAQM--------------------EELNQQ-
-VTT---SSEQLQSYQ-SDIIDLRR-AINALEIE--LQA------------QHSM--RD-
-----SLENTLNETEARYSSQLAQMQCMITNVES--------------------------
QLADIRCDLERQNQEYKILLDVK---ARLECEIATYQSLLESED---C---------KLP
CNPCTTP----------SSC----TP----------------------------------
----------CVPRTICVPR--TVCVPCTPCTP-----MSRY------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------IT---------MPYSCSL----PS-----
----LSC---S--------------CFSWPCVPRSCH----GSTLPW-SC-NIPVNVGNS
GCLC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLNS---
-------------------------RLASY-LE-KVRQLERDNA--ELESRIR-ERSQQQ
DPL--VCPDYQSHLRTIEELQQK--ILCTKAENTRLVVQIDNAKLAADGFRT---KY-EM
ELGLRQLVESDIN-------------------DLRRILDELTLCK--SDLEVQVESLKEE
-LLCLKSNHEEEANSLRR--QLGDRL--NVEVDAVP------------------------
---------------------------------------------------TVDLNNVLN
ETRSHYEAL----VESNH----RDVQEWFTRQT--------------------EELNGQ-
-VVS---SLEQLQSYQ-AEITEQRR-TVHALEVE--LQT------------QHNL--RD-
-----SLENTLTEMEARYSAQLAQVQCLISNVES--------------------------
QLAEIRRDLERQNQEYRVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACGKTIMPCD-SS-----------------------------
---ACTPCAPTARFSPCVPR-P-HCGP----------------CN--------SYTC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCP----PT-----
----PSC-RTS--------------CASRPCVPPSCH---G-CTLPG-AC-NIPANVGSC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLGSY-LE-KVRQLERENC--ELERRIQ-ERSQQQ
EPS--LCPSYQSYFRTIEELQQK--ILCNKAENARLVVEVDNAKLATDDFRT---KY-QS
ELSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------SVDLNRVLN
EVRSTYEAV----VETNR----REVEEWYTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLNESEARYSSQLSQVQCLIGSVES--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLDSED---CK---------LP
CNPCATT----------NACDKPIGPCVSNP-----------------------------
----------------CISR-S-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MPYAKPPPTVN----------------SIKGPQRK
ERLKPAHI----------HLQQLTCFSITCPST---------MSYSCCL----PS-----
----LGC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFTIIEELQQK--ILCAKAENARLVVNIDNAKLASDDFRS---KY-QT
EQSLRQLVESDIN-------------------SIRRILDELTLCK--SDLESQVESLREE
-LICLKKNHEEEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQLQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CNPCATT----------NASGNSCGPCGTS------------------------------
Q--KCC-CN---------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------S---AMRYN---------------------------YCLPN
MSCRSTC-------------------SSRPCVPPSCH----SCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 959)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESLIQ-ERCQPQ
EPL--LCPSYQSYFRTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEEEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--XX-
-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------
XXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX---X---------XLP
PNPCATT----------NACSKPIGPCVS-------------------------------
--------NPCAPCA---PP--TPCTPCAPRPR-----CGP--CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYSCFL----PS-----
----LSC-RST--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGSC
SWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-ERCQQQ
EPE--VCPNYQSYFRTIEELQQK--ILVSKSENARLVVQVDNAKLAADDFRT---KY-QT
ELGLRQLVESDIN-------------------GLRRILDELTLCR--SDLETQVESLKEE
-LISLKQNHEQEVNSLRS--RLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----RDVEEWFIKQT--------------------EELNRQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLSQVQGLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLESEINTYRGLLESED---CK---------LP
SNPCATT----------NAGDRSCI-----------------------------------
----------TNPCTPCVPR-P-RCGP----------------CN--------TFG----
-C--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-RTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
EMSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQLQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NAYEKSIGSCVTNAC----------------------------
-----------------GPR-S-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKNCAT-TMSSS---------------
------------------------------------------TPRKSCPGITNSEMLS-S
-N------------SSCQPGA---------LKTNSC-QPTGHVGRALPCQGCQSTPCL--
------CLTPV--------------CLVRN-----FI----T-----------CLSLDDC
GWCG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------SLQILNS---
-------------------------RLANY-LG-KVRMLEQENA--ELERKIQ-EESNKM
LPA--ICPNYRAYYTTIEELQQK--ILCTKAENSRLVSQIDNSKLTADDLRA---KY-QA
ELSQRQLAEADAN-------------------SLKQILDILTLGK--ADLETRVQSLKEE
-LLCLKTNHEKEIASLQS--QLGHRL--NIEVTAAP------------------------
---------------------------------------------------SVDLNRVLQ
EMRCQYESI----METNR----KDVEQWFNMQM--------------------EALKLQ-
-IDT---NSQEQQSCQ-KEIMELRR-TKNTLEVE--LQA------------QHQM--RD-
-----SQECILTETEAHYTGLLAQFQCLIDNLEA--------------------------
QLAEIRCSLERENQEYEILLDVK---SRLECEIATYRSLLENSD---G------K---LP
CNPCATK----------CEPPT-CMHSKARVM------------------------ECTA
P--VNTSV--------PAP--RGMCEPSCAYGA--LSRLLVKICT----------IT--E
EIQDGIVISSHEHVQ--------PCYIIRSAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LVC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDVGCQPGAE-ANVAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHN-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLL-ERSKCH
EST---------------ELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADQC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIE-------------------------
---------------------------------------------------------VLG
EMRAQYEAM----VETTA-----------GSQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--R------------QAQHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------PSCVT----AP-----------------------------CA-
---PRSSC---------GP--YTTCG-----ASTTGSQF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------LGYICQPGACVPSLCVST
TYHPTS---------------------------------------------RIFSSMGSC
SLYY---ESVFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TLQFLNS---
-------------------------RLAAY-LE-RVRQLERENV--ELERRLQ-EACDFQ
EPT--VGPNYLCCFKTIEELQQK--ILYSKAENARIVVQIDNTKLAADDFRS---KY-ET
ELGLRQLVEADTN-------------------GLRRILDELTLCK--ADLEMQVESLKEE
-LMCLKKNHEEEVGALRC--QLGDRL--NIEVDAVS------------------------
---------------------------------------------------PVDLNTVLE
EMRCRYEAL----VETNR----RDVEEWFTRQM--------------------EELNQQ-
-VVT---SSEQLQSYQ-SDIIDLRR-TVDTLEIE--LQT------------QHSL--RD-
-----SLENTLTETEARYASQLAQMQGLVTNVES--------------------------
QLAEIRCDLERQNQEYRVLLDVR---ARLEAEINTYRGLLDSED---C---------KLP
CNPCSTP----------SQP----SS----------------------------------
----------SVPRTVCVPR--TVCVPCVPCHP-----SCH-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGCT--TISCS---------------
------------------------------------------TPQQRCSRITNFQTIS-S
-N------------ANCQHSG---------LEANSR-QPTGHVLWA-----ARPTPCF--
------YFTPI--------------CLINN-----VN----A-----------CLPLDDC
GWCG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVRTLEKENA--ELECKIL-EECNKE
FCV--VCPDYMSYYATIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---KY-EA
EVSVRQLVEADAK-------------------GLQQILNALTLAK--ADLEAQVQSLREE
-LLFLKNKHEEEINSLQS--QLGDRL--NIEVTAAP------------------------
---------------------------------------------------SVDLNRVLQ
EMRCQYESI----METNR----REVEQWFNTQM--------------------EALNQQ-
-VVT---SSQQQQCCL-KEITELRR-TMNALEIE--LQA------------QHRM--RD-
-----SQECILVETEARYTALLAQIQCLVDNIEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEIAIYRSLLESSE---V------K---LL
CNPCATK----------CEPSS-KAS--AM--------------------------ECTA
L--VYNTPS-------SDS--RRTQEPCCAYRV--LPRILVKICT----------IT--Q
EIQDGKIISSHEHVQ--------PCFLIRIARV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTSTFSSGSV-RGLCGS
-------------------AGGFSRMSSFR-SGGSC-RVPRLAGTV----------GSGS
SFRL------------------------GLSGPGSFL---PGSCLST-GG-HPSGFLGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRELEQENA--GLEARIR-EWYECQ
VPY--ICPDYQGFFRTMEELQQK--ILLTKAENARLILQIDNAKLAADDFRT---KY-DS
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNTLRG--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
EMRCQYEAL----VENNR----RDVEIWFNTQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLSETEARYGSQLAQMQGLISSVES--------------------------
QLAEIRCDLERQNQEYRMLLDTK---ARLEQEIATYHRLLDSE---DC---------KLP
AHPCSTE----------YKPAVQSPYI---------------------------------
--------APCAPA-----------GSCVAAPQ-----VSTQIRT----------IT--E
EIRDGKVVSSREHLV--------PRLL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSNCCV-TNSLQTSVKSCP--
------------------------RPFSVCSSSMSG-RPELCLGYVCQPMACLSSICMPT
TFRPASGFSKT--------------YLSSSYQPSSCR---PVS--------GIASSMGTC
GWFR---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-ME-KVRQLERENA--ELEGKIQ-EACQAQ
VVT--LCPDYQSYFRTIEELQQK--ILCTRAENARMVVHIDNAKLAADDFRT---KY-EA
ELAMRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVSALRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRVLD
EMRCQYETM----VETNR----RDVEEWFNVQM--------------------EELSQQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TINTLEIE--LQA------------QHSL--RD-
-----SLENTLTETEARYSAQLAQMQGLITNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLEGEIDTYRGLLESED---S---------KLP
CNPCSTP----------ACAPCAPSP----------------------------------
----------GVPRTVCVPH--TVYVPCSPCPP-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFNQK-----------------SFRRTLSSSSQGPA---LSISSS
IYRKGG----------TQYLG----AAPSVYGGAGGHGTRIST-SR--RVVSYGSDQA--
---E---GNLWVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKM---------------------------------TMKNLND---
-------------------------RLASY-LE-KVRSLEQSNS--KFELQIK-QWYESN
TPG--ISRDHSAYLQQIQDLRNQ--IRDAQLQNARCVLQIDNAKLAAEDFRL---KY-ET
ERGIRLAVEADLQ-------------------GLHNVFDDLTLTK--TDLEIQIEELNKD
-LALLQKEHEEEVQSLRA--HLGNNV--NVEVDAAP------------------------
---------------------------------------------------SLNLSAIMS
EMRQKYEAM----AQENL----QKAKEQFQLQI--------------------ETLQQE-
-VTV---STEELKGAK-DEVKNHRR-TYQSLEIE--LQS------------HLST--KA-
-----ALEHTLEETKARYGAYLAKLQTQINSLED--------------------------
QLVQIRTDTEHQINEYNILLDIK---TRLEQEIATYRRLLEGED---YK---------T-
------TE---------YQLST--------------------------------------
-----------------------------LEEK--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EESI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLQAGFSSG-SLKSPGGA
-------------------GGVSTRVSTMN-SSSSC-KLPGLSRGARSFSAC--------
--------STG--------------LGRSSYRAASSL---PALCLPV-GGFATSYSM-GG
DWFG---EGILTGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1068)

EKE---------------------------------TMQFLNN---
-------------------------RLASY-LE-KVRQLERENL--ELEGRIR-EWCQQQ
VPF--MCPDYQSYFKTTEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
EVSLRQLVEADIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LMCLKKNHEEEVNALRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QQSM--RD-
-----TLESTLAETEARYSAQLAQMQGLITNVEE--------------------------
QLVEIRCDLERQSQEYQVLLDVR---ARLEGEIDTYRGLLESED---S---------KLP
CNPCAPD----------YSPSKPCVPCLPVA-----------------------------
------SCGSGTARTTCSPH-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PN-----
----FSC-RSS--------------CASRPCVAPSCH---S-STLPG-AC-NIPANVGNC
GWLC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELECRIR-ERCQPQ
DPC--VCPNYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
EQGLRQLVESDMN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
DTRSQYEAL----VETNR----RDVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLSQVQCMITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------N----A-------------------------------------
----CG------------SQ-S-RCGP----------------SS--------NFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SFHRSLSNSLQASV---VS----
---TVG----------TQRLG----MTPSVYGGAGGRGIRISN-SR--HTVNYGSDLT--
--GG---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKM---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRTLEQSNS--RLEVQIK-QWYETN
APR--AGRDYSAYYKQIEELRNQ--IKDAQLQNARCVLQIDNAKLAAEDFRL---KY-ET
ERGIRLTVEADFQ-------------------GLHKVFDDLTLHK--TDLEIQVEELNKD
-LALLKKEHQEEVDGLYK--HLGNTV--TVEVDAAP------------------------
---------------------------------------------------GLNLGAIMN
EMRQKYEVM----AQKNL----QEAKEQFERQT--------------------EVLQQQ-
-VTV---NTEELKGTE-VELTELRR-TSQSLEID--LQS------------HLSM--KE-
-----SLEHTLEETKARYSSQLANLQSLLSSLEA--------------------------
QLMQIRSDMERQNNEYHILLDIK---TRLEQEIATYRRLLEGED---VR---------T-
------TE---------YQLST--------------------------------------
-----------------------------LEER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EESI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSHSSPRCCSAEPCAA-----
----------------------------------NC-TSD--------PPCPTDTTCLPG
TCATSRCQTPS--------------FISRCHLPICCV---TPCHFAD-GC-NSPGVAGSC
PWCE---EGAFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-RVRSLEETNA--ELECRIR-EQCEPD
APL--VCPDYQCYFDTIEELQQK--ILCTKAENSRLAVQLDNCKLAADDFRS---KY-ES
ELSLRQMVETDIS-------------------GLRGILGELTLCK--SDLEAHVESLKDD
-LLCLKKNHEEEVNLLRD--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TVDLNKVLD
EMRCQYETV----LANNR----RDAEEWFAAQT--------------------EELNQQ-
-QLS---STEQLQGCQ-TEMLELKR-TANTLEIE--LQA------------QQSL--TE-
-----SLECTAAETEAQYSTQLAQMQCLIDSVEH--------------------------
QLEEIRCDLERQNQEYEVLLDTK---ARLECEIGRYRGLLESED---S---------RLA
CNPCSTA----------ST--------SSSA-----------------------------
-------CEPCSAYVICTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SLHRSLSSSSSGPA---LSMSGS
LYRKTS----------VQRLG----AAPSVYGGAGGHGTRISV-SK--SVTSYGSDLS--
--SG---GDLFAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKL---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRSLEQSNF--ALEAQIK-RWYETN
APS--TIKDYGPYYTQIKELQNQ--IKDAKIQNARCILQIDNAKLAAEDFRL---KF-ET
ERGMRITVEADLQ-------------------GLGKVFDDLTLQK--TDLELQIEELSKD
-LALLKKEHQEEVDVLRR--QLGNNV--NVEVDAAP------------------------
---------------------------------------------------GLNLGEIMN
EMRQKYEVL----AQKNL----QEAKEQFERQS--------------------EALQQQ-
-VTV---NTQELKGTE-VQVTELRR-TYQNLEIE--LQS------------HLSM--KE-
-----SLERTLEDTKARYASQLAAIQGMLSSLEA--------------------------
QLMQIRSDAERQNQEHNILLDIK---TRLEQEIATYRRLLEGED---VT---------T-
-----TKE---------YHLST--------------------------------------
-----------------------------LEAK--DTQKTRKIKT----------IV--Q
EVVDGKVVSSEIKEV-EENV--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSTGSV-KGLCGT
-------------------AGGISRVSSIR-SVGSC-RVPSFGGAA----------GSVS
SARL------------------------GLSGLGSCL---PGSYLSS-GC-HPSGFVGTG
GWFC---EGSFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELERRIR-EWYESQ
IPY--ICPDYQSYFKTIEDFQQK--ILLTKAENTRLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVSALRG--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKVLD
EMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLENTLAETEARYGSQLAQMQCLISNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLECEINTYRRLLEGED---C---------KLP
AHPCATE----------CKPAARVPYVPS-------------------------------
--------VPCAPA-----------VPCTPAPQ-----LSAQIRT----------IT--E
EIRDGKVICSREHLQ--------PRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTTQLCTPAFSTGST-RGLCGS
-------------------TGSFSRMSSIH-TMGSC-KASGLVGTG----------GSMS
TFRT------------------------GLSGFGSCL---PGSYLFS-GY-PSSGFGGNG
GWFS---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQVLND---
-------------------------RLASY-LE-KVRQLERENA--ELEQRIR-EWYECQ
IPY--VCPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKRSHEEEVNALRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-NVNALEIE--LQA------------QQSM--RN-
-----SLESTLAETEARYSSQLAQMQCMITNVES--------------------------
QLADIRCDLERQNHEYQVLLDVK---ARLESEIATYRRLLEGED---C---------KLP
AHPCATE----------CKPTMRVSYAPS-------------------------------
--------GSCIP------A-----GPCTPAPQ-----VSTQIRT----------IT--E
EIRDGKVISSREHVL--------PRL--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------Y

PF00038 // ENSGT00900000140814_1_Domain_1 (571, 1068)

-LE-RVRGLEQENE--ALECKIR-EQCELE
VPL--VCPDYQCYFNTIENLQQK--ILCTKAENSRLAVQIDNFKLAADDFRS---KY-ET
ELSFHQLVEADIS-------------------GLQKILDDLTLCK--RDLEAHVESLKED
-LLCLRKNHDEXXXXXXX--XXX--X--XX-XXXXX------------------------
---------------------------------------------------XXXXXXXXX
XXXXXXXXXXXXXXXXXX----XXXXXXXXXXX--------------------XXXXX--
-XXX---XXXXXXXCQ-SEILELKR-RANALDIE--LQA------------QHGL--IE-
-----SLECTKTETETQYGTQLAQMQCLIDNVES--------------------------
QLADIRCDLERQNEEYQVLLDTK---ALLECEIATYQSLLESED---C------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MT-SNCST-SIKSCP--
------------------------RPSSVCSSSMSC-RPELCLGYVCQPMTCMPSVCLPS
TYRPASCLSKT--------------YLSSSCWPSSCR---PTS--------GISSSVGTC
SWYC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENT--QLESKIQ-EACQSQ
AAT--MCPDYQSYFRTIEELQQK--VLCTKAENARIVVHIDNAKLAADDFRT---KY-ET
ELAMRQLVEADTS-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKKNHEQEVSALRC--QLGDHL--NIEVDAAP------------------------
---------------------------------------------------PVDLNRLLE
EMRCQYETV----VESNL----RDVEEWFNTQM--------------------QELNQQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLESTLAETEGRYGSQLAQVQHLIVNVEL--------------------------
QLAEIRSDLERQNQEYKVLLDVK---ARLESEIATYRGLLESED---C---------KLP
GNPCSTP----------SRPTCAPSP----------------------------------
----------SMARTICVPR--TVCVPCVPCPP-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKDCST-TSSSS---------------
------------------------------------------TPCQGCSRITNFRIIS-S
-N------------TSCQQ-----------LETSKC-QPTGHVLRTFQSQGCQPTPCF--
------CPMPI--------------CLVPN-----V----------------------DC
GWCG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

HEKE---------------------------------TMQILND---
-------------------------RLANY-LE-KVRMLEQENA--ELECKIQ-EECNKE
LPV--ICPDYLSYFSTIKELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLQRILNALTLGK--ADLEARVQSLKEE
-LLCLKSDHEKETNSLQS--QLGDRL--NIEVTAAP------------------------
---------------------------------------------------SVDLNRVLQ
EMRCQYESI----METNR----RDVEQWFNTQM--------------------EELNQQ-
-VET---SSQQQQCCQ-KEIIELRR-TMNALEVE--RQA------------QHRM--RD-
-----SQECLLAETEARYTALLAQMQCLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SQLECEIATYRRLLESSD---S------K---LS
CNPCATI----------GEPSV-CT-----TM------------------------ECTA
P--VYTP-S-------SAL--QGIPEPSCAYED--LPRLLAKILT----------IT--K
EIKDGKVISSHEHVQ--------PCFIIRAAKA-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------NEI--------------------------------
----ETANM------------------------------ACNCGPPNCSSSASFKSHSRL
-L----T-------------------SKALSACPGY-PSRSHGISQCQAKAYPPNACHPI
P-----YRSPI--------------YLLNN-----FR----V-----------SSGEASC
GWSV---EGSFDS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQMLNQ---
-------------------------RLASY-LE-KVRRLEQENA--SLECRIR-EQHERQ
TPV--LCPDYLSYFKIIEELQQK--ILCTKAENSRLVSQIDNTKVAADDFRA---KY-ET
EVSQRQLVEADTN-------------------SLHQILNALTLCK--ADLEGRVESLKEE
-LLELKHNHEEEVNSLQC--QLGDRL--NIEINAAP------------------------
---------------------------------------------------SVDLNQALQ
KMRCKYESL----VESNR----RDVEEWFNTQL--------------------QELSQQ-
-VVS---SSEQQQGFQ-KEILDLRH-NISALEIE--LQA------------QHSL--RT-
-----SQECILTETEGRYAIQLAQIQCLIETVES--------------------------
QLAEIRCTLERQNQEYQVLLDVK---SKLECEIATYRHLLENTD---C------K---LP
CNPCALE----------CKPSP-HRPCKAQDT------------------------ERMV
P--VYVPCKLCSLYAPSV---------CNLCST--LPGILARIYT----------LT--Q
EVQDGKVISSREHVQ--------PRFIPRLQVH-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MEFTGR-----------------SFHRSLSSSLQGPA---LSMRGS
MYGKGG----------MQHFG----AAPSVYGGAGGQGIRIST-SR--PMVGYGSDLT--
---R---GDVFAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NDKM---------------------------------TMQNLND---
-------------------------RLASY-LE-KVHSLEQSNS--KLELLIK-QWYETN
TPG---IRDDSAYYQQIKELQNQ--IKSVQLQNFHCVLQIDNAKLAAEDLRL---KY-EA
ERETRLTVESDIQ-------------------GLNKVSADLSLSR--TDLEIQIKELTKD
-LDLLKKEHQEEVDSLRR--HLGDTV--CVEVDAAP------------------------
---------------------------------------------------GLELGTVMN
ELRQKYETI----VQENL----QKAKEQVSNY----------------------------
--------VEAIKDNE-AQVKELRH-TYRNLEIE--LQS------------HLSM--KE-
-----SLERTLEETRARYGSQLATIQALLNSIEA--------------------------
QMTQIWSDTERQNKEYNILLDIK---TRLEQEIATYRRLLEGED---VI---------QT
NT---TIE---------HLPST--------------------------------------
-----------------------------LEEK--DVKRKRKIKT----------IV--E
EVVDGKVVSCETKEM-EEDV--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----SN-----
----VSC-RSS--------------CSSRPCVPHSCH----GCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 727)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEARIQ-ERNQQQ
EPL--VCPSYQSYFRTIEELQQK--ILCTKSENSKLVVEIDNAKLAADDFRT---KF-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRYS-SQ------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------LSQVQCMITNVES--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACGKPIGPCV-AN-----------------------------
---PCTPCAPPAPCTPCVPR-S-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYSCGL----PN-----
----MSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--VCASYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLASDDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-VEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQRLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACDKSTGPCISNPC----------------------------
-----------------GPR-A-RCGP----------------CN--------TFGY---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGCTT-VSS-----------------
-----------------------------------------SMPLQSCSGITNFRTISSN
--------------QGCQGT----------------------------------------
-------GLES-----------------NSCPAVPRV-SHVPIYLT--SHFDACLPLVDC
TWXX---XX-XXXXXXX---------------------------------XXXXXXX---
-------------------------XXXXX-XX-XXXXXXXXXX--XXXXXXX-XXXXXX
XXX--XXXX

PF00038 // ENSGT00900000140814_1_Domain_1 (610, 1068)

XXXXXXXXXXXXXX--ILCTKAENSRLVSQIDNTKVAADDLRA---KY-EA
EVSGRQLVEADAK-------------------GLQQILNMLTLGK--ADL----------
----------EEINSLQS--QLGDRF--NIEVTAAP------------------------
---------------------------------------------------SVDLNQILQ
EMRCQYESI----VETNR----RDVEQWFTMQM--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEIE--LQA------------QHRM--RD-
-----SQECILVETKARYTALLAQIQRLIDSLEA--------------------------
QLAEIRCALERQNQEYEILLDVT---SHLESEIATYRSLLESSD---S------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSFYSTS-SCP----LGC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDVGCQPGAE-ANAASMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---KNTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELETTLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADKC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-HLSLKSNHEQEVKILRS--QLGEKF--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQ----------AQHTL----KD-
-----CLQNSLCEAEDRYGTELAQMQSLISNLEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------ASC--------------------------------------T-
---SCPSC---------GP--VTGGSPSG-YGASTGR-----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYRSS-SCP----LGC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDFGCQPGAE-ANIAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELEATLL-ERSKCH
EST--VCPNYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADKC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----LETNR----QDVEQWFQAQS--------------------EGISLQ-
-DMS---CSEELQCCQ-SEILELRC-TVNALEVE--R------------QAQHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---TRLENEIATYRNLLESED---C------K---LP
CNPCSTP----------PSCVT----AP-----------------------------CA-
---PRPSC---------GP--CTTCGPTC-GASTTGSRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVFSCLSQ-IT----------------NVF-----
----------------KLTSRAPLPPCT--------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH----GYTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
EQSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQMESLKEE
-LLSLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQTG--------------------ELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQRLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACEKPIGSCVTNP--------------------------C-G
P------------------R-S-CCGP----------------CN--------TFGY---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PN-----
----LSC-RST--------------CSSRPCVPPSCH---T-CTLPG-AC-NIPANVGNC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-EWCQQQ
EPY--VCPSYQSYFRTIEELQQK--ILCAKSENARLVVQIDNAKLAADDFRT---KY-ET
ELGLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEEEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNRVLN
RQ--------------------------VLFQT--------------------EELNKQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLAQVQCLISNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACGSAGS-----------------------------------
----CVSN-SCAPCTPCVPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYTCCL----PA-----
----LSC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 733)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRELERENA--ELERRIQ-ERNQQQ
EPL--LCASYQSYFRTIEELQQK--ILCNKSENARMVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLSLKQNHEPGLAGASFQLPQAC------------------------------------
------------------------------------------------------------
---CTKEAV----LQTNG----F-------------------------------------
------------------------------VEDE--LEA------------GR----R--
-----------RKEGGQLGEEERSQLMLLSSVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVA-------------------------------
--------------NPCISR-S-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MTS---------------------
------------------------------------------------------------
-----HRC----SSLRGGQVPE-AKAASLCLSATVAHANRARVGS---TPLGQPSLCMPH
SCCT-AC------------------------------------PLPG-TC-NIPGNIGVC
ENYA---EGVPNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKV---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERDNE--ELETRIR-ESSKCH
EST--MCPDYQSYFQTIEELQQ--KILCIKSENNKLVVQIDNAKLAADDFRT---KY-QT
EHSLCQLGEADIC-------------------GLRRALDDLTLAK--SDLEAQLESLKEE
-VLCLKKNHEQEVHILKC--QLGDKL--QIKLDVEP------------------------
---------------------------------------------------TVDLSRVLQ
EMRCHYEAL----VQTNH----NDLEEWFQDQS--------------------ESISKQ-
-DMS---CAEELRCCQ-SEILELRR-TVNALEVE--LQA------------QHTL--KD-
-----CLQNSLCEADARFGTELAQMQILISNVEE--------------------------
QLSEIRADLERQNQEYEELLDTK---ARLEGEINTYRNLLESED---C------K---LP
CNPCATP----------ASS------TP-----------------------------RP-
---APAACTPCSPCLSGPP--RASCGS---------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LGC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDVGCQPGAE-ANIAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADKC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----LETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-THTLVRVL--HPHFSLGALYILSPYFPLQ--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---TRLENEIATYRNLLESED---C------K---LP
CNPCSTP----------PSCVT----AP-----------------------------CA-
---PRPSC---------GL--CTTCGPTC-GASTTGSRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---S-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKSNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----REVEQWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CN---------LP
SNPCATT----------NACSKPIGPCLSNPC------------------------T---
------PCVPPAPCTPCAPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-RTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NAYEKSIGSCVTNAC----------------------------
-----------------GPR-S-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----SN-----
----LSC-GSS--------------CPSRPCVAPSCH---D-IPLPG-AS-NIPANVGNC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIQ-ERCQQQ
EPL--MCPSYQSYFRTIEELQQK--ILCAKSENARLVIQIDNAKLASDDFRT---KY-EM
EHSSRQLVESDIN-------------------SLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----LETNR----RDVEEWYTNQT--------------------QELNKQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEGRYSSQLSQVQCMITNVEE--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLECEINTYRNLLESED---CN---------LP
CNPCATT----------NACGNS-------------------------------------
----CGPC----------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGSTV-TISSS---------------
------------------------------------------TPPQNCSGNTNFRTNSSS
-N------------KS-CHD---------------G-QSTGRALQTPQGQGCGSSPCL--
------YRCPH--------------YLIRT-----YS----F-----------HPCLNDG
SWCT---EGI-NTH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1063)

EKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVRMLEGENT--DLEEKIQ-EACSKA
LPI--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---NY-EA
ELSLRQLVEADAN-------------------GLKQILDALTLSK--ADLEARVQSLTEE
-LLCLKTNHEEEVNSLQC--QLGDRI--NIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCRYESI----METNR----KEVEEWFNTQM--------------------EELNQQ-
-VVS---SSQQQQCYQ-KDIIELRR-TISALEVE--LQA------------QHRM--RE-
-----SQECILTETEARYTALLAQIQSLIHNLEA--------------------------
QVADIRSALQRQNQEYEVLLDIK---SRLECEIATYRSLLESLD---G------R---LP
CNPCATK----------WEPS-----CQARAM------------------------ECFT
P--VFTS---------SSL--PGIHKPCRASGP--PSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCYITRAAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MT---
--S--DHC----SSLLSEQVSE-AKAASLCLLANVAHANQVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TR-HIPGNIGIC
GAYS---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERDNA--ELETKLR-ERSKCH
ESS--VCPDYQSYFCTIQELQQ--EILCTKSENNRLVVQIDNAKLAADDFRT---KY-ET
ERLLHQLVEADIC-------------------GLRRVLDNLTLAK--CDLEAQLESLKEE
-LLCLKKNHEQEARTLRG--QLGDKL--RIELDIEP------------------------
---------------------------------------------------TIDLSRVLG
EMRGQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRR-SVNALEVE--LQA------------QHTL--KD-
-----CLQNSLCEAEDRYGTELAQMQSLINNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---FP
CNPCATP----------AFS------TP-----------------------------SP-
---APAACAPC---SW------ATHGLCSSAGY---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKAGFSSG-SLKGLGGA
-------------------GGASSRVPAMY-SSSSC-KLPSLSRGSRSFSAS--------
--------SAG--------------VGRGSYRAASCL---PALCLPAAGGFAASYGG-GG
GWFG---EGILSG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELEGRIR-EWCEQQ
VPY--MCPNYQSYFQTIEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-EM
ELSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LMCLKKNHEEEVNSLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNQQ-
-VVS---SSEQLQNCQ-AEITELRR-TVSALEIE--LQA------------QHSM--RD-
-----ALESTLVETEARYSSQLAQVQCMVTNVEA--------------------------
QLAEIRCELERQNQEYQVLLDVR---ARLEGEINTYRGLLESED---C---------KLP
CNPCSPD----------SSSSKSCLPYLPAA-----------------------------
------SCGPSAVRATCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MPSICMPT
TYRSASCLSKT--------------YLSSSCQPSNRR---PTS--------CVSSSMGTY
GLFY---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQVLND---
-------------------------RLASY-LE-KVRQLERDNA--ELEGKIQ-DVYQAQ
VLT--MCPDYQSYFQTIEELQQK--VLCTKAENARMIVHIDNAKLAADDFRT---KY-ET
ELAMRQLVEADTN-------------------GLRRILDELTLNK--ADLEAQVESLKEE
-LLCLKRNHEEEVGVLRQ--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRMLE
EMRCQYETM----VETNH----RDVEDWFNMQM--------------------EELNKQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLGETEGRFTSQLSQMQCMITNVES--------------------------
QLANIRCDLERQNQEYKVLLDVK---ARLECEIDTYRGLLESED---S---------KLP
CNPCSAA----------ACQPCAPSP----------------------------------
----------GVSRPVCVPH--TVCVPCSPCLQ-----SRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDGSPSCCSSEPCAGAS---
----------------------------------SC-ATA--------SLCPTNTTCLPN
TCSASRCQTPS--------------FLCRASLPACCL---SPCYLAG-GC-NSPCLVGSC
AWCE---EGTFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-RVRSLEENNA--ELECRIR-EQCEPD
APL--VCPDYQRYFDTIEELQQK--ILCTKAENSRLAVQVDNCKLAADDFRS---KY-ES
ELSLRQLVENDIT-------------------GLRGILGELTLCK--SDLEAHVESLKDD
-LLCLKKGHEEEVNLLRE--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TVDLNKVLD
EMRCQYERV----LADNR----RDAEEWFAAQT--------------------EELNQQ-
-QRS---SAEQLQGCQ-TEMLELKR-TANTLEIE--LQA------------QQTL--TE-
-----SLECTVAETEAQYSTQLAQMQCLIDSVEH--------------------------
QLAEIRCDLERQNQEYQVLLDTK---ARLECEINTYRGLLEKED---S---------RLP
CNPGSRA----------PRPNTTCEPCSNST-----------------------------
-------CEPCSAYVICTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSSG-SLKSPGGA
-------------------GAGSARVSTMY-SSSSC-KLPRGSRGAKSFSAY--------
--------SAG--------------LGRNNYRVASCL---PALCLPN-GGFATSFSM-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFRTMEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
EVSLRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWYDTQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-ADMIELRR-TVNSLEIE--LQA------------QQSM--RD-
-----ALDSTLAETEARYSSQLSQMQCMIGNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---C---------KLP
CNPCAPD----------YSPSKSCLPCLPAA-----------------------------
------SCA-GAARTTCSPR-----PVCVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------RLYAKPSPTIK----------------GIKGQLRK
EKLILTHI----------HLQEFIYSSITSPSI---------MPYTCCL----PS-----
----LSC-RTS--------------CSSRPCVPHSCR----SSTLPG-AC-NIPANVGSC
GWPC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LQ-RVRELERENA--ELEGRIQ-EFNQQQ
EPI--VCPNYQSYFRTIEELQQK--ILCAKSENSRLVVQIDNAKLASDDFRT---KY-ET
EVSLRQLVEADIN-------------------SLRRILDELTLCK--SDLEAQVESLREE
-LVFLKKNHEEEVNSLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNSVLN
ETRAQYEAL----VQTNR----RDVEEWFTRQT--------------------EELNRQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSTQLSQVQYMITNVES--------------------------
QLGEIRSDLERQNQEYQVLLDVR---ARLEGEINTYRGLLESED---CK---------LP
VNPCATT----------NASGSSRGSCGSCQT------------------------RC-Y
---------NL-------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MELAHR-----------------SLQRSLSSSSQGPA---LS----
---KGS----------VQRFG----VAPSVYGGAGGHNTRIST-SR--QVVGY-------
---G---GDLFAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKT---------------------------------AMQNLND---
-------------------------RLASY-LD-RVRSLEQSNS--QLELQIK-QWYDVN
APA--ATRDYSAYYKQIEELQNQ--XXXXXXXXXXXXXXXXXXXXAMD--DR---EY-EN
ERGLRLTVEADVQ-------------------GLTKVFDDLTLKK--TDLEIQVEELNKD
-LALLKKEHQEEVATLRR--ALGSTV--SVEVDAAP------------------------
---------------------------------------------------SLNLSAVMN
EMRQKYEIM----AQENI----QKAKEQFEFQI--------------------EALQQE-
-VTV---GTEELKISE-SQIKELRH-TYQNLEIE--LRS------------HLSM--KE-
-----ALERTLEDTKARYGAQLAAMQTRLSLLEN--------------------------
QLMQVRSDTEHQISEYHILLDIK---TRLEHEIATYRHLLEGED---VT---------N-
------TE---------FQLST--------------------------------------
-----------------------------LEEK---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKAGFSSG-SLKSPGGA
-------------------SGGSTRVSAMY-SSSSC-KLPSLSRGDRSFSAC--------
--------SAG--------------VGRSSYRATSCL---PTLCFPV-GGFTTSYSV-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFRTIEELQKK--TLCSKAENARLVVEIDNAKLAADDFRT---KY-ET
EVSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNQQ-
-VVS---SSEQVQSCQ-AEIIELRR-TVNTLEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYTSQLAQMQCMITNVET--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYQGLLESED---S---------KLP
CNSCAPD----------YSPSKSCLPCLPAA-----------------------------
------SCGPSAARLTCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PA-----
----LSC-HTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGSC
NWFC---EGSFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENC--ELERRIQ-ERNQQQ
EPL--LCPSYQSYFRTIEELQQK--ILCNKAENARLVVEVDNAKLATDDFRT---KY-ET
ELSLRHLVESDIN-------------------GLRRILDELTLCR--ADLEAQVESLKEE
-LLSLKQNHQQEVNTLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------SVDLNRVLN
EVRSTYEAV----VETNR----REVEEWYTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHTL--RN-
-----SLENTLNESEARYGSQLSQVQGLIGSVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLDSED---CK---------LP
CNPCATT----------TACEKPIGPCIA---------------------------N---
---P------------CISR-S-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKAGFSSG-SLKSPGGA
-------------------SGSSTRVSAMY-SSSSC-KLPSLSHGARSFSAC--------
--------SAG--------------LGRSSYRATSCL---PTLCLPA-GGFTTSYSV-SG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQDNA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFRTIEELQKK--TLCSKAENARLVVEIDNAKLAADDFRT---KY-ET
EVSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----QDAEDWFDTQT--------------------EELNQQ-
-VVS---SSEQVQSCQ-AEIIELRR-TVNTLEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQMQCMITNVET--------------------------
QLTEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
CNPCAPD----------YSPSKSCLPCLPAA-----------------------------
------SCGPSAARLTCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------HANRVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERDNA--ELETKLR-ERSKCH
ESS--MCPNYQSYFCTIQELQQ--KILCTKSENNRLVVQIDNAKLAADDFRT---KY-ET
ERSLHQLVEADIC-------------------GLRRVLDNLTLAK--CDLEAQLESLKEE
-LLCLKKNHEQEARTLRG--QLGDKL--RIELDIEP------------------------
---------------------------------------------------TTDLSRVLG
EMRGQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRR-SVNALEVE--LQA------------QHTL--KD-
-----CLQNSLCEAEDRYGTELAQMQSLINNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVR---ARLEGEINTYRSLLESED---C------K---FP
CNPCATP----------AFS------TP-----------------------------SP-
---APAACAPC---SW------ATHGPCSSTGY---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDCSSTHCSPESCTTAS---
----------------------------------GC-APA--------SSCCIETACLPS
ACATSRCHTPS--------------FLPRSRGLTGCL---LPCYFTG-SC-NSPCLVGDC
AWCE---DGVFTS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRSLEETNA--ELESRIQ-EQCEQD
IPT--VCPDYQCYFNTIEDLQQK--ILCTKAENSRLAVQLDNCKLATDDFKS---KY-ES
ELSFRQLLESDIS-------------------GLHGILDELTLCK--SDLEAHVESLKED
-LLCLKKNHEEEVSLLHG--QLGDHL--SVELDTAP------------------------
---------------------------------------------------TLDLNRVLD
EMRCQYETV----LANNR----REAEEWFAVQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSSQLAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLEGEINTYRGLLDSED---S---------RLS
CNPCSTT----------CT--------SSNT-----------------------------
-------CEPCSAYVICTV--ENCCL----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSSG-SLRGLGGA
-------------------GGGSARVSAMY-SSSSC-KLPSLSRGARSFSAC--------
--------SVG--------------LGRSSSRAAGCL---SALCLPA-GGFTTSYNL-GG
GWFG---DGVLTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLERENA--SLEGRIR-EWCEQQ
VPY--LSPDYQSYFRTIEELQKK--TLCTKAENARLVVQIDNAKLAADDFRT---KY-ET
ELSMRQLVESDMN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEEWFNTQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-AEIIELRR-SVNALEIE--LQA------------QQSM--RD-
-----ALESTLAETEARYSSQLAQMQCLISNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRGLLESEE---G---------KLP
CNPCAPD----------HTPAKSCLPCLPAV-----------------------------
------SCGPGAVRSTCSPR-----TICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------LS--
------------------------WKRVFLSSCMSC-WPERCLGYICQPGACVPSLCVST
TYQPTS---------------------------------------------RIFSSMGSC
SLYY---ESVFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TLQFLNN---
-------------------------RLAAY-LE-RVRQLERENV--ELERRLQ-EACDFQ
EPT--VGPNYLCCFKTIEELQQK--ILYSKAENARIVVQIDNTKLAADDFRS---KY-ET
ELGLRQLVEADTN-------------------GLRWILDELTLCK--ADLEMQVESLKEE
-LMCLKKNHEEEVGALRC--QLGDRL--NIEVDAVS------------------------
---------------------------------------------------PVDLNTVLE
EMRCRYEAL----VETNR----RDVEEWFTRQM--------------------EELNQQ-
-VVT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQT------------QHSL--RD-
-----SLENTLTETEARYASQLARMQGLVTNVES--------------------------
QLAEIRCDLERQNQEYRVLLDVR---ARLEAEINTYRGLLDSED---C---------KLP
CNPCSTP----------SQP----SS----------------------------------
----------SVPRTVCVPR--TVCVPCVPCHP-----SCH-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSAGSA-KGLCGT
-------------------SGSFSRISSIH-SMGSC-RAPSLVGTV----------GSVS
SFRT------------------------GFSGPGSCL---PGSYLSS-GC-HSSGFAGSG
GWFC---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKA---------------------------------TMQILND---
-------------------------RLANY-LE-KVRQLEQENT--QLECRIR-EWYECQ
IPY--ICPDYQSYFKTAEELQQK--ILLTKSENARLILQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKRNHEEEVNALRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYETL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNSLEIE--LQA------------QQSM--RN-
-----SLESTLAETEARYSSQLGQMQCLITNVES--------------------------
QLAEIRCDLERQNHEYQVLLDVK---ARLESEIATYRRLLDGED---C---------KLP
AHPCSTE----------CKPAVRVPYIPS-------------------------------
--------TTCTPAGPCTPA-----GPCTPAPQ-----VSTQIRT----------IT--E
EIRDGRVISSREHVV--------PRAM-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSSG-SLKGPGGA
-------------------IGVSTPVSTMY-SSSSC-QLPSLSWGARSFSAC--------
--------STG--------------LGRSSCRAASCL---PTLGLPI-GGFATSYSL-GG
SWFG---EGVLNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQVLND---
-------------------------RLANY-LE-KVRQLEQENT--SLEGRIR-EWCEQQ
VPY--MCPDYQFYFRTIEELQKK--TLSTKAENARLVVQIDNAKLAADDFRT---KY-EI
ELSMRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEANSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----WDAEDWFITQT--------------------EELNQQ-
-VVS---SSEKLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHSL--RD-
-----ALDSTLAETEARYSAQLAQMQHLISNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
CNPCAFN----------YSPSKSGLPCLPAA-----------------------------
------SCSPGTIRMSCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PS-----
----ISC-RTS--------------CASRPCLPPSCH---G-CTLPG-AC-NIPSNIGTC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWCQQQ
VPY--VCPDYQNYFRIIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------SLRRILDNLTLCK--SDLEAKVESLKEE
-LLCLKQNHEQEVNTLRC--QIGERL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRILN
ETRCQYETV----VENNR----RDVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQNCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLSQVQCMITNVED--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEIATYQGLLESED---CK---------LP
CNPCATT----------NACGKPIGPCPIS--------------------------N---
---PCGPCG------PCAPR-S-RCGP----------------CN--------SFIC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PN-----
----FSC-RSS--------------CASRPCVAPSCH---S-STLPG--C-NIPANVGNC
GWLC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELECRIR-ERCQPQ
DPC--VCPNYQSYFKTIEELQQK-----------RLVVKIEHSKLASDDFRP---KY-ET
ELGLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
DTRSQYEAL----VETNR----RDVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLSQVQCMITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CN---------LP
CNPCATT----------NASENS-------------------------------------
----CV------------QH-T-RCGP----------------CK--------TFMY---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSAGSA-KGLCGT
-------------------TGSFSRISSIH-SMDSC-RAPSLVGTV----------GSVS
SFRT------------------------GFSGPGSCL---PGSYLSS-GC-HSSGFAGSG
GWFC---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKA---------------------------------TMQILND---
-------------------------RLANY-LE-KVRQLEQENA--QLECRIR-EWYECQ
IPY--ICPDYQSYFKTAEELQQK--ILLTKSENARLILQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKRNHEEEVSALRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYETL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QQSM--RN-
-----SLESTLAETEARYSSQLGQMQCLITNVES--------------------------
QLAEIRCDLERQNHEYQVLLDVK---ARLESEIATYRRLLEGED---C---------KLP
AHPCSTE----------CKPAVRVPYIPS-------------------------------
--------TTCTPTGPCTPA-----GPCTPAPQ-----VSTQIRT----------IT--E
EIRDGRVISSREHVV--------PRAM-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDGSPTCCSSESCARAS---
----------------------------------DC-AFA--------STCSVDTTCLPS
TPATSRCQTPS--------------FLSRSRLPTGCL---TPCYLAG-TC-N-PCMVGNC
AWCE---DGVFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRGLEEMNA--ELECRIR-EQCEED
LPL--VCPDYQCYFDTIEELQQK--ILCTKAENSRLAVQLDNCKLAADDFRS---KY-ES
ELSLRQLVETDIG-------------------GLRGILDELTLCK--SDLEAHVESLKDD
-LLCLKKNHEEAVSLLRE--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TIDLNRVLD
EMRCQYETV----LANNR----RDVEEWFAVQT--------------------EELNQQ-
-QVC---STEQLQDCQ-AEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSTQLAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYEVLLDTK---ARLECEINTYRGLLESED---S---------RLP
CNPCSAI----------ST--------SSNT-----------------------------
-------CEPCSAYVICTV--ENCCT----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MPSSCCV-TNTSSASLKSSA--
------------------------RPSSVCSSNMGS-RSELCLGYVCQPLQCMPSVCMPT
TYRPASCLSKT--------------YLSSSCQPSNRR---PNG--------CISSSMGTY
GLFC---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQVLND---
-------------------------RLANY-LE-KVRQLEKENA--ELEGKIQ-DVYQGQ
VLT--MCPDYQSYFQTIEELQQK--VLCTKAENARMIVHIDNAKLAADDFRT---KY-ET
ELALRQLVEADTN-------------------GLRRILDELTLNK--ADLEAQVESLKEE
-LLCLKRNHEEEVGVLRQ--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRMLE
EMRCQYETM----VETNH----RDVEEWFNMQM--------------------EELNKQ-
-VAT---SSEQLQGYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLGETEGRFTSQLSQMQCMITNVES--------------------------
QLADIRCDLERQNQEYKVLLDVK---ARLECEIDTYRGLLESED---S---------KLP
CNPCSTP----------SCQPCAPSP----------------------------------
----------GVSRSVCVPR--TVCVPCSPCLQ-----TRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSSGSV-KGLCGP
-------------------AGSICRVSSIR-SVGSC-RVPSLAGVA----------GSVS
SVRL------------------------GLSGLGSCL---PSSCLPA-GY-HSSGFVGTG
GWFY---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERDNA--ELECRIR-EWCQQQ
EPY--VCPNYQSYFKTIEELQQK--ILMTKSENARLVLQIDNVKLAADDFRT---KY-ET
ELSMRQVVEADIN-------------------GLRRILDELTLCK--ADLEMQVESLKEE
-LMCLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKVLD
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------QELNQQ-
-VVS---SSEQLQCYQ-TDIIELRR-TVNALEIE--LQA------------QHST--RN-
-----SLESTLAETEARYSSQLAQMQCLITNVEA--------------------------
QLAEIRCDLERQNHEYQVLLDVK---ARLESEIATYRRLLEGED---C---------KLP
AHPCATE----------CKPAIRVPYLPS-------------------------------
--------MSCATS-----------VPCTSGPQ-----ISTQIRT----------IT--E
EIRDGKVISSREQVQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSCYISS-SQC----PGS----------
------------------------------------------------TRLPAPTSV---
--Y--GPS----MDLVTQPGAE-ARAASLCLSATVAHANRPRVGA---TPLGKPSLCMPF
SCCT-AC------------------------------------PLPG-TC-NIPGNIGVC
ENYA---EGAPNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKV---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERDNE--ELETKIR-ESSKCH
EST--MCPDYQSYFQTIEELQQ--KILCSKAENTRLIIQVDNAKLAADDFRI---KH-ES
ELSLRQMVEADMC-------------------GMHKLMDDLSLAK--ADLEAQQESLKEE
-LLCLKKNHEQEVSILRS--QLGDKL--QIKLDVEP------------------------
---------------------------------------------------TVDMSRVLQ
EMRCHYEAM----VQTNH----NDLEEWFQDQS--------------------ESISKQ-
-DMS---CSEELRCCQ-SEILELRR-TVNALEVE--LQA------------QHSL--KD-
-----CLQNSLCEADARFGTELTQMQVLISNVEE--------------------------
QLSEIRGDLERQNQEYQVLLDVK---ARLECEIATYRKLLESED---C------K---LP
CNPCSTS----------ASCVT----TP-----------------------------CA-
---PRPSCTPCN-TCV--P--GPACGTSIGSRF---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSSG-SLKSPGKA
-------------------AGGSTRVSNMY-SSSSC-KLPNPSRGARSFSVC--------
--------SAG--------------LGRGNYRVSSCL---PALCLPT-GGFAASYGM-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFRTMEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
EVSLRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWYDTQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-SDIIELRR-TVNSLEIE--LQA------------QQSM--RD-
-----ALDSTLAETEARYSSQLAQMQCMIGNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
CNPCAPD----------YSSSKSCLPCLPVV-----------------------------
------SCSTGAARTTCSPR-----PVCVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MNREHCPGAE-ANAASMCLLANVAHANRVRVGL---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---KNTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELETTLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADKC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-HLSLKSNHEQEVKILRS--QLGEKF--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQ----------AQHTL----KD-
-----CLQNSLCEAEDRYGTELAQMQSLISNLEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------ASC--------------------------------------T-
---SCPSC---------GP--VTGGSPSG-YGASTGR-----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYSCGL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELENLIR-ERSQQQ
EPL--VCASYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLASDDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQRLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCTTT----------NACDKSTGPCISNPC----------------------------
-----------------GLR-A-RCGP----------------CN--------TFGY---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
EQSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLHC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQRLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACEKPIGSSVTNLC----------------------------
-----------------VPR-S-RCGP----------------CN--------TFGY---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLRL------------------------GLSGLGSCL---PGSYLSS-GC-HTSGFVGNG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWYESQ
IPY--ICPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVSVLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILE
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQVQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRRLLEGED---C---------KLP
PPPCATA----------CKPVIRVPSVPP-------------------------------
--------VPCVPA-----------VPCTPAPQ-----VGTQIRT----------IT--E
EIRDGKVISSREHVQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKAGFSSG-SLKSPGGA
-------------------SGGSTRVSAMY-SSSSC-KLPSLSRGARSFSAC--------
--------SAG--------------LGRSSYRATSCL---PTLCLPA-GGFTTSYSV-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQDNA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFRTIEELQKK--TLCSKAENARLVVEIDNAKLAADDFRT---KY-ET
EVSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNQQ-
-VVS---SAEQVQSCQ-AEIIELRR-TVNTLEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQMQCMITNVET--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
CNSCAPD----------YSPSKSCLPCLPAA-----------------------------
------SCGPSAARLTCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MAFSNR-----------------SFQMGSSTRFQTSA---PSVSGL
SVRSSS----------IQKL-----QAPSVYGGAGGYGTRISTGTS--LGPNFGGSFQLN
VTGN---DVLLAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKS---------------------------------TMQNLND---
-------------------------RLASY-LE-RVRSLEKANS--LLEKQIK-EWYEKN
VTH--VRQDHSAYLKTIEDLQNK--ISVAHLENARLVLQIDNAKLAADDFRL---KF-EN
ELLLRQSVENDIN-------------------GLLRVRDDLTLTK--SDLESQIENVNEE
-LLFLKRNHEEEVDRLQK--QVGGSV--NVEVDAAP------------------------
---------------------------------------------------SIDLATTME
NMRRQYEEM----AEKNR----QEAKERFEKQT--------------------EELNLE-
-VAI---NMEQLQEQK-REITERRQ-VYQSLELE--LQS------------HLNM--KK-
-----ALEDTLDETEARYTYQLNQIQEAVARLEA--------------------------
QLRQLRSDMEAQNNEYSILLDIK---TRLEMEIATYRRLLEGED---SR---------SA
QVN--------------LHAEE--------------------------------------
-----------------------------TEKA--ESNKIKKIKT----------IV--E
EVVDGKVVSSEVKEI-EEKI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----SN-----
----VSC-RSS--------------CSSRPCVPHSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 969)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEARIQ-ERKQQQ
EPL--VCPGYQSYFRTIEELQQK--ILCAKSENSKLVVNVDNAKLASDDFRT---KY-ET
ERSLRQLVESDIN-------------------SLRRILDELTLCR--ADLEAQVESLKEE
-LLSLKRNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNQVLN
ETRSQYEAL----VETNR----REVEEWFTTQE---------------------------
------------------------------------------------------------
--------NTLTESEARYSSQLSQVQCMITNVES--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRSLLDSED---CN---------LP
CNPCATT----------NATGNSCGPCSS---------------------------S---
---QKCCS----------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------ASDDAPWGCSAESCVQA----
---------------------------------------------------------APN
AHLSSRCQTPS--------------FICRSHLTTGCL---TPCYYAG-TC-HSPCLVGNC
TWCE---EGTFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRSLEEANE--ELECRIQ-EQCEPE
APV--VCPDYQCYFDTIEELQQK--ILCTKAENSRLAVQLDNCKLAADDFRS---KY-ES
ELSLRQLVESDIS-------------------GLRGILSELTLCK--ADLEAHVESLKDD
-LLCLKESHEEEVNVLRD--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TMDLNKVLE
EMRCQYETL----LANNR----RDAEEWFAAQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEMLELKR-TANTLEIE--LQA------------QQNL--TK-
-----SLECTVAETEAQYGTQLAQMQCLIDGVEN--------------------------
QLAEIRCDLERQNQEYEVLLDTK---ARLECEINTYRGLLDSED---S---------RQL
NL--------------------KLIPPPSNT-----------------------------
-------CEPCTAYVICTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------SSDCSSMPCSPESCTRAS---
----------------------------------CC-APA--------SSCSMETACLPG
SCGASRCQTPS--------------FLSRSLGLTGCL---LPCYFTG-SC-NGPCLVGNC
AWCE---DGVFTS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRSLEETNA--ELESRIQ-EQCEQD
IPL--VCPDYQCYFNTIEDLQQK--ILCTKAENSRLAVQLDNCKLATEDFKS---KY-DS
ELSLRQLLEADIS-------------------GLRGILGELTLCK--SNLEAHVESLKED
-LLCLKKTHEEEVNLLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TLDLNRVLD
EMRCQYETV----LANNR----REAEEWFAVQT--------------------EELNQQ-
-QLS---STEQLQGCQ-MEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTMAETEAQYSSQLDQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLEGEINTYRGLLDSED---S---------RLS
CNTCSTT----------CT--------PSNA-----------------------------
-------CEPCSAYVICTV--ENCCL----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MMSKCCVT-SSL-----------------
-----------------------------------------QTSVKSCPRPSS--VCSSS
--------------VSCRPE-----------------LCL---GYVCQPVTCMPSICMPT
TYRPAGCSSKTYL--------------PSSCRP-T---------------SGITSTMGTC
NWFC---EGTFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 911)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQDNA--NLENKIQ-EACQSQ
VLT--MCPDYQSYFRTIEELQQK--VLCTKAENARMVVHIDNAKLAADDFRT---KY-ET
EVSLRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LMCLRKNHEKEVSTLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRMLD
EMRCQYETM----VETNQ----RDVEEWFNTQX--------------------XXXXXX-
-XXX---XXXXXXXXX-XXXXXXXX-XXXXXX-------------------XXXX--XX-
-----X----XX-X-XXXXXXXXXXXXXXXXXXX------XXXX-XXX-XXXX-------
XXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX---XX---------LP
CNPCST-S---------SCFPCVPSP--CV------------------------------
---PRTV---------CVP--PTVCVPCSPCPP--GRY----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------ASDCSPTGCSSESSARAS---
----------------------------------DC-ALA--------STCSVETTCLPS
ACATSSCQTPS--------------FPSGARLPTGCL---PPACFAG-SC-NIPCVVGNC
AWCE---DGVFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRGLEELNA--ELECRIR-EQCEED
VPL--VCPDYQCYFDTIEDLQQK--ILCTKAENCRLAVQLDNCKLAADDFRSKY----ES
ELSLRQLVETDIS-------------------GLRGILGELTVCR--SDLEAHVESLKDD
-LLCLKKSHEEEVNVLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TTDLNRVLD
EMRCQYETV----LANNR----RDVEEWFAAQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANTLEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSSELAQIQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYRVLLDTK---ARLECEINTYQGLLDSED---S---------RLP
CNPCSAT----------SM--------SNDT-----------------------------
-------CEPCSAYVICTV--ENSCP----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYSCGL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--VCASYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLASDDFRT---KY-ET
EMSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQLQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACDKSIGPCISNPC----------------------------
-----------------GPR-A-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYSCCL----PT-----
----LSY-RSS--------------CSSRPCVPHSCR---G-TTLPG-AC-NIPANVGSC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELESRIL-ERSQQQ
EPL--LCPNYQSYFRTIEELQQK--ILCAKSENSRLVIQIDNAKLAADDFRT---KY-ET
ERSLRQLVESDIN-------------------SLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEANSLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRAQYEAL----VETNR----RDVEEWYIRQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEVE--LQA------------QHNL--RD-
-----SLENTLTETEARYSCQLAQVQGLIGNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRGLLDSED---SK---------LP
CNPCATT----------NASSISCRSSAQ-------------------------------
----------NRCC----------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MASKCLKA-SFSAGSLK---------SP-
-----------------------------------------GRPSGGSPRVSAMYSS--S
-SCK-LPS------LSRGTRS--FSAFSAGLGRSSY-RVASCLPTLC-------------
--------------------------------------------LPA-GG-FAISYGGGG
GWFG---DGMLTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

SEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLERDNA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFQTIEELQKK--XXXXXXXXXXXXXXXXXXXXXXXXXXX---XX-XX
X--XXXXXXXXXX-------------------XXXXXXXXXXXXXXXXXXXXXXESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-AELIELRR-TVNALEIE--LQA------------QHSM--RD-
-----ALESTLAESEARYSSQLAQMQCMIGNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---C------K---LP
SNPCAPD----------YSPSKSCLPCLPA------------------------------
-----ASCSPGAIRATSSP--RPICVPCPGGRF---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MFSLPVTP
--------------KDVSRR-----------------SVHRSLSSSLQGS----------
---AVS----------MQHLG----MAPSVYGGAGGRGTRISTTSR--NTVSYGSDLI--
--GS---GDLFVGNEKM---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRALEESNS--KLEVQIK-QWYEAN
APS--GGRDDSAYYRQIEELRNQ--IKDAQLINSRCILQIDNAKLAAEDFRL---KF-ET
ERGIRLTVEADLQ-------------------GLSKVFDDLTLQK--TDLEVQIEDLNRD
-LALLKKEHQEEVDSLHR--HLGNTV--NVEVDAAP------------------------
---------------------------------------------------GRNLGAIMN
EMRQKYEDM----AQKNL----QEAKEQFER-----------------------------
--------------------------------------------------------

PF00038 // ENSGT00900000140814_1_Domain_1 (957, 1068)

-KE-
-----SLEHTLEETKARYSIQLANLQSLLSSLEA--------------------------
QLMQIRSDTERQNNEYHILLDIK---TRLEQEIATYRRLLEGED---VK---------I-
------TE---------YQLST--------------------------------------
-----------------------------QEEK--DIKKTRKIKT----------VV--E
EVVDGKVVSSEVREV-EENI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PA-----
----MSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 872)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-ME-KVRQLERENA--ELECRIQ-ERNQQQ
DPL--VCPAYQAYFRTIEELQQK--ILCGKSENARLVVQIDNAKLASDDFRT---KY-ET
ELSLRQLVEADIN-------------------SLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWYTTQR---------------------------
----------------------------------------------------------N-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLGEIRADLERQNQEYQVLLDIR---SRLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVPNP-----------------------------
----------------CVTR-P-RCGP----------------CN--------TFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKRLKAGFSSG-SLKSPGGA
-------------------SGGSTPVSAMY-SSSSC-KLPSLSRGARNFSAC--------
--------SAG--------------LGRSSYRAASCL---PTVCLPA-GGFATSYSV-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQENA--ELESRIR-EWCEKQ
VPY--MCPNYQSYFQTIEELQKK--TLCSKAENARLVVEIDNAKLAADDFRT---KY-EM
EVSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRALD
EMRCQYETL----VENSR----RDAEDWFDTQT--------------------EELNQQ-
-VVS---SAEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQMQSLITNVEA--------------------------
QLAEIRADLERQNQEYQVLLNVR---ARLECEINTYRGLLESED---S---------KLP
CNPCAPD----------YSPSKSCLPCLPAA-----------------------------
------SCGPSAARTTCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYISS-SCP----LGA----------
------------------------------------------------KIP-GAEN----
------VF----IDVGCQPGAE-AKVAFPCLLANVAHANRVRVGS---TPLGRPSLCLPQ
SCRT-AC------------------------------------PLPG-TC-HIPGNIGIC
GSFG---EGSLNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

HEKE---------------------------------TMQFLND---
-------------------------RLANY-LQ-KVRQLEKENA--ELETGIR-EISKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIIQVDNARLAADDFRI---KH-ES
EHSLRQLVEADMC-------------------GMQKLLDDLTLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRG--QLGDKL--RIELDTEP------------------------
---------------------------------------------------TIDLSRVLE
EMRCQYETM----VETNR----RDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELKC-KVNALEVE--RQA------------QHNL--KD-
-----CLQNSLCEAEGRYGTELAQMQSLITNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARL-CEIATYRNLLESED---C------K---LP
CNPCSTP----------ASCLA----PA-----------------------------CA-
---PRPSC---------AS--RTTCGPGSVCGVSTGSRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFTHR-----------------SLHRGLSSSSEGPA---ISVSGS
THRKGA----------MQYLA----AAPSVYGGAGGQGIRISN-SR--HMMSYGGDPS--
---G---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1063)

NGKM---------------------------------TMQNLNE---
-------------------------RLANY-LA-KVQSLEKSNA--KLELQIK-QWYETN
TPG---TRDHSAYYQQIEELQNQ--IKKVQLENAHCVLQIDNARLAAEDFKL---KY-ET
ERALHLTVEGDIR-------------------GLNKVLGDLSLTR--TDLEIQIKELSKD
-LDILKKEHQEEVDSLRK--HLGNTV--SVELDAAP------------------------
---------------------------------------------------CLNLGTTMN
EMRQKYEVI----AQENL----QKAKEQFEKQT--------------------QALQQQ-
-VTL---SNEELKETE-AHVKELRR-TYQNLEIE--LQS------------LLSL--KE-
-----TLEHTLEDTKDRYSRKLATIQGVMDNLEA--------------------------
QLVQIRKDTERQSNEYNILLDIK---TRLEQEIATYRRLLEGDV---IK-----------
-----TTE---------DDLSI--------------------------------------
-----------------------------SEEK--DIKRKRKIRT----------VV--E
EVVDGKVVSYQSKEE-EEDL--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYSCSL----PA-----
----LSC-RTS--------------CSSRPCVPPSCH---G-YTLPG-AC-NIPTNMGNC
TWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRELERENA--ELERRIQ-ERSQQQ
EPL--LCPSYQSYFRTIEELQQK--ILCNKSENARLVVQIDNIKLAADDFRT---KY-ES
ELSLRQLVESDIN-------------------GLRRTLDELTLCK--SDLEAQVESLKKE
-LLCLKQNHEQEVNTLSC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------SMDLNRVLN
EVRNTYEAL----VETNR----REVEEWYTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLAQVQQLISSVES--------------------------
QLAEIRGDLERQNQEYQVLLDMQ---SRLEGEINTYRGLLESED---CK---------LP
CNPRATT----------NACDKPIVPYVI---------------------------K---
---P------------CLTR-PRRCGP----------------CG--------PFGH---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSSCCV-TSTLPVSLKSSS--
------------------------RPSSVCSSNMGS-RPELCLGYVCQPLQGMSSICMPT
TYRPASCLSKP--------------YLSSSCQPSNRR---PTG--------CISSSMGTY
SLIC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEGKIQ-DVYQAQ
VVT--MCPDYQSHFQTIEELQQK--VLCTKAENARMIVHIDNAKLAADDFRT---KY-ET
ELALRQLVEADTN-------------------GLRRILDELTLNK--ADLEAQVESMKGE
-LLCLKKSHEEEVGVLRQ--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRMLE
EMRCQYETM----VETNH----RDVEEWFNMQM--------------------EELNKQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLGETEARYTSQLSQMQCMITNVES--------------------------
QLADIRCDLERQNQEYKVLLDVK---ARLECEIDTYRGLLESED---S---------KLP
CNPCSAP----------SGQPCAPSS----------------------------------
----------GVSRSVCMSR--TVCVPCSPCLQ-----SRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

PF00038 // ENSGT00900000140814_1_Domain_1 (656, 1075)

RY-QM
EHSLYQLVEADIC-------------------GLRRALDDLTLAK--CDLEAQVESLKEE
-LLCLKKNHEQEVHTLTC--QLGDRL--LIELDTEP------------------------
---------------------------------------------------TVDLSRVLE
EMRCQYETM----VETNR----HDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRR-TVNALEVE--LQA------------QHHL--KD-
-----CLQNSLCEAEARFGTELAQMQCLISTVEE--------------------------
QLAEIRADLERQNQEYQVLLDVK---ARLEGEI-TYRNLLESED---F------K---LP
CNPCTTP----------ASS------TP-----------------------------CP-
---APAACTPCPPCPSRPL--QASRGPCSSPQR---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSDR-----------------SLQLSLSPSSQVSE---LNEGGF
RYRKRV--------------M----AAPSVYGGAGGHGTRIST-FS--PMVHSGNEIH--
---T---CNLFVD

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1063)

NEKI---------------------------------TMQSLNE---
-------------------------RLANY-LK-NVHHLEHSNS--RLEVQIK-QWYETN
SAS--TRRDYSEYYQQIQELQHQ--VKDALLKNARCVLQIDNAKLAAEDFKI---KY-EI
EKSMRLTVESEIQ-------------------SLKKVCDELTLLK--TDMEIQIEELNKD
-LAVLKKEHQEEVDCLKK--QLGKTV--NVEVDAPP------------------------
---------------------------------------------------GQNLGTIMN
EMREKYEAM----AQKYL----QDAKEQFDLQI--------------------GTLQQQ-
-VTV---STEELKGTE-LQIKELSH-HHQNLKIQ--FHT------------QLSM--KE-
-----SLARTLEETKARYSGQLAKIQALLKSLET--------------------------
QLRQIRTELECQNKEYDILHDIK---TQLEHEIATYRSLLEGVD---VT---------T-
------TG---------FPLNI--------------------------------------
-----------------------------PEEI--DRKATRKTKT----------DV--Q
VIVDGKVVLSEVNET-EETV--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MPYAKPPPTVN----------------SIKGPQRK
ERLKPAHI----------HLQQLTCFSITCPST---------MSYSCCL----PS-----
----LGC-HTS--------------CSSRPCVPPSCH----SHTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFTIIEELQQK--ILCAKAENARLVVNIDNAKLASDDFRS---KY-QT
EQSLRRLVESDIN-------------------SIRRILDELTLCK--SDLESQVESLREE
-LICLKKNHEEEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNRVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEVRYSSQLSQVQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CNPCATT----------NASGNSCGPCGTS------------------------------
Q--KCC-CN---------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SFHRSLSNSLQASV---VS----
---TVG----------TQRLG----MAPSVYGGAGGRGIRISN-SR--HTVNYGSDLT--
--GG---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKM---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRTLEQSNS--RLEVQIK-QWYETN
APR--AGRDYSAYYKQIEELRNQ--IKDAQLQNARCVLQIDNAKLAAEDFRL---KY-ET
ERGICLTVEADFQ-------------------GLHKVFDDLTLHK--TDLEIQVEELNKD
-LALLKKEHQEEVDGLYK--HLGNTV--NVEVDAAP------------------------
---------------------------------------------------GLNLGAIMN
EMRQKYEVM----AQKNL----QEAKEQFERQT--------------------EVLQQQ-
-VTV---NTEELKGTE-VELTELRR-TSQSLEID--LQS------------HLSM--KE-
-----SLEHTLEETKARYSSQLANLQSLLSSLEA--------------------------
QLMQIRSDMERQNNEYHILLDIK---TRLEQEIATYRRLLEGED---VR---------T-
------TE---------YQLST--------------------------------------
-----------------------------LEER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EESI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYSCVL----PS-----
----LSC-RTS--------------CSSRPCVAPSCH---S-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEVRIQ-ERCQEQ
DPL--VCANYQSYFRTIEELQQK--ILCAKSENARMVMKIDNTKLASDDFRT---KY-ET
ERSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQVESLREE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTRQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLAQVQCMVTNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEIETYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVTNPC------------------------G---
------------------PR-P-RCGP----------------CN--------TFVC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------ST---------MSYSCVL----PS-----
----LGC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGNC
NWFC---EGSFNGR

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1069)

EKE---------------------------------T---------
-------------------------------------------T--ELESRIQ-ERCQEQ
DPL--VCANYQSYFRTIEELQQK--ILCSKSENARLVVQIDNAKLASDDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLREE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VDTNR----REVEEWFTRQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLAQVQCMVTNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEIETYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVSNPC------------------------TP-R
V--RC--------------------GP----------------CN--------TFVC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MLYARPPPTIN----------------GIKGLQRK
ERLKPAHI----------HFQQLTCLSITCPGT---------MSYSCCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEHLIQ-ERSQQQ
EPL--LCASYQSYFKTIEELQQK--ILCGKAENARLVVQIDNAKLASDDFRT---KY-QT
EQSLRRLVESDIN-------------------SLRRILDELTLCT--SDLEAQVESLREE
-LLCLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VDTNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQSLISNVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CNPCATT----------NASANSCGPCGTSQK----------------------------
---CCCN-----------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSNIIRT-SSCY---PLG----------
------------------------------------------------SKLPGATNI---
--S--ISS----IDVGGKPGAQ-VKAASMCFSAAMAHNNRVRVGT---TSLGRPSLCLPN
SCWS-AC------------------------------------PIPG-AV-NIPANIGNC
GNYG---EGFLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELETKIQ-EWSKCH
PSF--VCPDYQSYFRTIEELQQ--KILCTKAENNRLVIQVDNAKLAADDFRI---KY-ES
ELSLRKLVEADMC-------------------GMHKLMDGLTLAK--CDLEAQVESLKEE
-QLSLKSNHEQEVHNLQC--QLGDKL--HIELDTAP------------------------
---------------------------------------------------PVDLNRVLG
EMRCQYEAM----VETNR----NDVEQWFLAQS--------------------EGISMQ-
-EMS---CSEEIQCCQ-SELLELRC-SVNALEIE--RQA------------QHKM--KE-
-----CLENSLCESEARYSTELAQMQYLISNVEE--------------------------
QLSEIRADLERQNNEYQVLLDVK---ARLECEISTYRNLLESED---C------K---LP
CNPCATP----------ASCVP----PP-----------------------------CG-
---PRPSCAPRTTCVPPR----SACGTNMSGRF---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSTCCV-TNSLQTSVKSYP--
------------------------RPSSVCLGSVSC-RPEPCLGYVCQPVARLPSACVPT
TFRPASCVSKT--------------FLSSSCWPSSCR---PAS--------GILSFMGPS
GWYG---EGAFSG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLNE---
-------------------------RLASY-LE-KVRQLEQENA--ELEGKIQ-EASQTQ
VLT--TCPDYQSYFRTIEELQQK--VLCTKAENARMVVHIDNAKLAADDFRT---KY-EA
ELAMRQLVEADIS-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEQEVSALRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRVLE
EMRCQYEAM----VETNR----RDVEDWFNMQM--------------------EELNQQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLAETEGRYSSQLAQVQCMVTNVEA--------------------------
QLAEIRCDLERQNQEYQMLLDVR---ARLEGEINTYRGLLESED---C---------KLP
ENPCTTS----------SCPPCAPST----------------------------------
----------CVPQTICVPR--TICVPCVPCPQ-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDSSPTSCSSEPHAGVS---
----------------------------------DG-ATA--------STCSTETTGLPN
TCATSRCQTPG--------------FLSTSRLPTTCF---VPCYLAG-SC-NLPCMVGNC
AWCE---DGVFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NERE---------------------------------TMQFLND---
-------------------------RLASY-LE-RVRGLEEMNA--ELECRIR-EQCGGD
IPL--VCPDYQCYFDTIEDLQRK--ILCTKAENSRLTIQLDNCKLAANDFRS---KY-ES
ELSLRQLVETDIG-------------------GLRGILDELTLCK--ADLEAQVESLKED
-LLCLKKHHEEEINLLRG--QLGDRL--TVELDSAP------------------------
---------------------------------------------------NIDLNGVLN
EMRCQYETV----LANNR----RDVEEWFAAQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-IEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSTQLAQMQCLIDNVEE--------------------------
QLAEIRCDLERQNQEYQVLLDTK---ARLEGEISTYQGLLESED---S---------RLP
CNPCSTT----------SV--------SSNT-----------------------------
-------GEPCSAYVLCTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSTG-SLKSPGGA
-------------------AGGSTRVATMY-SSSSC-KLP---RGPRSFSVC--------
--------PAG--------------LGRSSFGAASCL---PAPCFPA-GGFAASYGVAG-
GWFG---EGVLTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLERENS--ELEGRIR-EWCEQQ
VPY--MCPDYQAYFRTIEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGNRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----REAEDWFDTQT--------------------EELNQQ-
-VVS---SSEQLQGCQ-AEIIELRR-TVNALEIE--LQA------------QQSM--RD-
-----ALESTLVETEARYGSQLAQMQGLIGSVES--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLDSED---C---------KLP
GNPCAPD----------HAPSKSCLPCLPPS-----------------------------
------SCSPGTARTTCSPR-----PVCVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQFCSPIFSSGSV-KGLCGT
-------------------SGGISRVSSVR-SVGSC-RVPSLAGVG----------GSAS
SIRL------------------------GLSGFGSYL---PGSCLSS-GY-NSSSFAGSG
GWFC---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERDNA--ELESRIR-EWYESQ
IPY--ICPDYQAYFKTIEELQQK--ILITKADNARLVLQIDNAKLAADDFRT---KY-ET
ELGMRQLVEADTN-------------------GLRRILDELTLCK--ADLEMQVESLKEE
-LICLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-NVNALEIE--LQA------------QHSM--RN-
-----SLEATLAETEARYSSQLAQMQGLISNVEA--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLESEIATYRRLLEGED---C---------KLP
AHPCATE----------CQPAVRVPYVSS-------------------------------
--------VP-----------------CAPAPQ-----LSTQIRT----------IT--E
EIRDGKIISSREHLQ--------PLALL------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTQGSTA-AMSPS---------------
------------------------------------------APPQNCSGITNSRSIS-S
-Y------------NTCHHG---------------G-PEANSCQPTGQGRGCQSTLCI--
------CCTPS--------------NLMSS-----FS----S-----------RPCLDNC
AWHW---EGI-NSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1068)

EKE---------------------------------TMQLLND---
-------------------------RLANY-LE-TVRKLEGENA--ALECRIR-EVRDQE
GPA--VCPEYLSYFATIEKLQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-EA
EVSLRQLVDADTN-------------------ALRQILDALALGK--ADLEVRVQSLKEE
-LLCLKTNHEEEVSSLQS--QLGDRL--TIEVTAAP------------------------
---------------------------------------------------SVDLTQVLQ
KMRCQYESI----METNR----KDVEQWFSAQM--------------------EELSRQ-
-VVA---RAHQQQCCQ-AELTELRR-TLTALEVE--RQA------------QHRM--RD-
-----SQERILEETEARYTTLLSQIQGLIHSVEG--------------------------
QLAEIRGALERQNQEYESLLDTK---SRLECEIATYRSLLESWD---C------T---LP
CYPCATK----------SEPSV-GGSCNVKVR------------------------ECPA
P--VYTS---------SVP--TVTCK---TCGP--LSPILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCYITRSAQV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------SFHGSLSSSLQGSA---LSPS--
---TRG----------MLRLG----AAPSVYGGAGGRGTRIST-RR--HMVSYASNFT--
--GG---GDLFLG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKT---------------------------------IMQNLND---
-------------------------RLASY-LE-TVRSLEQSNF--KLEAQIK-QWYETH
APS--TGRDYSAYYNQIKELQNQ--IKDAHLQNAQCVLKIDNAKLAAEDFKL---KY-ET
ERGMRLTLEADLQ-------------------GLNKIFDDVTLLK--TDLELQIENLNRD
-LALLKKEHEEEVDSLRR--HLGNTV--NVEVDAAP------------------------
---------------------------------------------------GLNLSAIMD
DMRQKYEVM----VQKNI----QDAKEHFERQT--------------------KTLQQQ-
-VQV---NTEELKGTE-SQLRELRH-TSQSLEIE--LQS------------HLSM--KE-
-----SLKHTLEETNARFRGQLDNLQALLQSLEA--------------------------
QLMQIRSNTESQNAEYTILLDLK---IRLEQEIATYRRLLEGED---VK---------T-
------TE---------YQLNT--------------------------------------
-----------------------------LEER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EEQLAINSCHKKMLLKF-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MEFTRR-----------------SLHRGLSSSSQGSA---HSVSGS
IYRKGG----------MQHFG----AAPSVYGGAGGQGIRISN-SS--QKMSYGNDDT--
---K---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKT---------------------------------TMQNLNE---
-------------------------RLASY-LA-KVQSLEQSNS--QLELQIK-QWYETK
TPS---TRDYSAYYQQIEELQNQ--IKNAQLENVHCVLQIDNTKLAAEDFKL---KY-ET
ERGLRLAVESDIQ-------------------GLNKVLGDLSITR--TDLEIQIKELSKD
-LDILKKEHQEEVDSLHR--HLGNTV--NVELDAAP------------------------
---------------------------------------------------SLNLGTIMN
EMRQKYEVI----AQENL----QKAKEQFEKQT--------------------QTLQQQ-
-VTV---SSEELKETE-AQVKELRR-TYQNLEIE--LQS------------LLSL--KE-
-----TLEHTLEDTKDRYSSKLVTIQAVLDNLEA--------------------------
QLVQIRTDMERQSNEYNILLDIK---TRLEQEIATYRRLLEGED---VV---------TK
RTKNSTTE---------SALSI--------------------------------------
-----------------------------PEEK--DIKRKRKIMT----------VV--Q
EVVDGQIVSCETKEM-EEDL--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSDGSPTGCPSESCAGAS---
----------------------------------DC-AIA--------SSCSLETTCLPN
ACAASRCQTPS--------------FLSRSHLPASCI---TPCHFAG-SC-NIPCLVGNC
AWCE---DGVFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRGLEEMNA--ELECRIR-EQCEED
VPL--VCPDYQCYFDTIEDLQQK--ILCTKAENSRLAVQLDNCKLAADDFRS---KY-ES
ELSLRQLVETDIS-------------------GLHGILGELNLCK--ADLEAHVESLKDD
-LLCLKKNHEQEVNLLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TIDLNGVLD
EMRCQYETV----LANNR----REAEEWFAVQT--------------------EELSQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANALEIE--LQA------------QQSL--TE-
-----SLECTVAETEAQYSSQLAQMQCLIDNVEN--------------------------
QLAEIRCDLERQNQEYEVLLDTK---ARLEGEINTYRGLLESED---S---------RLS
YNPCPTT----------SM--------PRNT-----------------------------
-------CEPCSAYVICTV--ENCCS----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------T----------GYIS
SARS------------------------GLSGLGSCL---PGSYLSS-GC-HSSGFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWYESQ
IPY--ICPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVSVLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILE
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNTLEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRRLLEGED---C---------KLP
PPPCAMA----------CKPAIRVPSVPL-------------------------------
--------VPCAPA-----------VPCTSAPQ-----VGTQIRT----------IT--E
EIRDGKVISR-EQVQ--------SRLL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGRTT-TNSPS---------------
------------------------------------------TPCQSCSRITNVSTIS-S
-N------------NSCQR-G--G------LKVNNR-QPAGHVQRIFQDQGCRPTLCS--
------CCMPI--------------YLLNN-----FN----A-----------RSSLDDC
SWYS---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNN---
-------------------------RLANY-ME-KVRMLERENA--ELESKIQ-EESNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSKIDNTKLAADDLRA---KY-EA
EVSLRQLAEADAN-------------------GLKQILNVLTLGK--ADLEVQVQSLKEE
-LLCLKNNHKEEINSLQC--QLGEKL--HIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCHYESI----METNR----KDAEQWFNAQM--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRC-TVNTLEVE--LQA------------QHRM--RD-
-----SQECILTETEARYTALLTQIQSLIDNLEV--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEITTYRSLLESLD---G------K---LP
CYPCATK----------CEPSP-WTSCKSRAM------------------------ECTA
P--ACTS---------SAS--CGLQEPCSACGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPTKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LVC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDVGCQPGAE-ANVAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHN-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADQC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----VETNR----QDLEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQ----------AQHTL----KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNMEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------ASC--------------------------------------T-
---SCPSC---------GP--VTGGSASG-HGA---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSDG-----------------SFHWSPNSSQV-----------S
AMRAVG----------MQHRV----TAPSVYGGAGGHGIRIST-FR--HMGNYGNELN--
---G---GNLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKM---------------------------------IMQNLND---
-------------------------RLANY-LQ-KVHSLELSNS--KLEMQIK-QWYETN
APS--SSRDYSAYYKQIEELRNQ--IKDELLKKAQCILQIDNAKLASGDFKL---XX-XX
XXXXXXXXXXX-X-------------------XXXXXXXXXXXLK--TDLEIQIEELNKD
-LALLKKEHQEEVTG-KK--LLGNNV--NVELKAAP------------------------
---------------------------------------------------GLNLGAIMN
EMREKYEAM----AQKYL----QDAKEQFETQI--------------------VTLQQK-
-VTV---STEELKGTE-SQIKEQRR-NYQNVEIE--FQT------------QLSM--KE-
-----SLERALEETKARYSGKMVTIQAILTSLET--------------------------
QLKQIRTDIERQNKEYNILLDMK---TRLEQEIATYRRLLEGED---IX---------X-
------XX---------XSLST--------------------------------------
-----------------------------LEEK--DIMKTRKIKT----------VV--E
EIVDGKIVSSEVKEM-EENI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LVC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDVGCQPGAE-VNVAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHN-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADQC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----LETNR----QDLEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--R------------QAQHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNMEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLETED---C------K---LP
CNPCSTP----------PSCVT----AP-----------------------------CA-
---PHSSC---------GP--CTTCG-----ASTTGSRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MYSS--S
-SCK-LPS------LSHGART--FSAFSAGLGRSSC-RAASCLPVLCLPAGGFATSY---
--------------------------------------------------------SMGG
GWFG---DGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------T---------
M-----QSLN--DR-L-A-SY-L-EK-VR--Q------LEKENA--ELESRIR-EWCEQQ
VPY--MCPDYQSYFRTIEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---XX-XX
XXXXXXXXXXXXX-------------------XXXXXXXXXXXXX--XXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXX--XXXXXX--XXXXXXXX------------------------
---------------------------------------------------XXXXXXXXX
XXXXXXXXX----XXXXX----XXXXXXXXXXT--------------------EELNQQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQIQCMITNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---C------K---LP
CNPCAPD----------YSPSKSCLPCLPA------------------------------
-----ASCGPGVARTICSP--RPVCV---PCPG--GR-F---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MTSSYSSS----SCLLGCT-M-AP----------------GGR-----
----------------NACVSPIDTGCQPGAEA---------KAASMCLL---ANVA-HA
NRVRVGS-TPL--------------GRPSLCLPPTCH---TACPLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1069)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESQLR-ERSKCH
EST--VCPDYQSYFRTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKSNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNQVLN
QTRSQYEAL----VDTNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQSMISNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACEKPIGSCVTNS-----------------------------
----CC------------PR-S-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LVC----------
------------------------------------------------TMAPGARNV---
--S--VCP----IDVGCQPGAE-ANVAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHN-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADQC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----LETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--R------------QAQHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------PSCVT----AP-----------------------------CA-
---PRSSC---------GP--YTTCG-----ASTTGSRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGCTT-TNSPS---------------
------------------------------------------TPSQNCSRITNVSTIS-S
-N------------NCCHS-G--G------LKVKNC-QPAGHTLRTTRDQGCQPTPCF--
------CRKPI--------------YLINN-----FI----L-----------HSSLDDC
SWYG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVRMLERENA--ELESKIQ-EENNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLKQILNVLTLGK--ADLEAQVQSLKEE
-LLCLKNNHKEEINSLQC--QLGERL--HIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCQYESI----METNR----KDVEQWFNTQI--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEVE--LQA------------QHRM--RD-
-----SQECILTETEARYTALLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEITTYRSLLESLD---G------K---RP
CYPCTTK----------CEPSP-WTSYKSGAM------------------------ECTA
P--ACTS---------SAP--CGLKEHCSAYGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDAKGRTT-TNSPS---------------
------------------------------------------TPCQSCSRITNVSNIS-S
-H------------NSCQC-G--G------LEVNNR-QPAGHVQRIFQDQGCQPAPCS--
------CCVPI--------------YLVNN-----FN----A-----------HSSLDDC
NWYS---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNN---
-------------------------RLANY-ME-KVRMLERENA--ELESKIQ-EESNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLKQILNVLTLGK--ADLEVQVQSLKEE
-LLCLKNNHKEEINSLQC--QLGERL--HIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCHYESI----METNR----KDAEQWFNTQM--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEVD--LQA------------QHRM--RD-
-----SQECILTETEARYTALLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEITTYRSLLESLD---G------K---LP
CYTCATK----------CEPSP-WTSCKSRAM------------------------ECTA
P--ACTS---------SAS--CGLQEPCSACGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYSCGL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELENLIR-ERSQQQ
EPL--VCASYQSYFKTIEELQQK--ILCGKSENARLVVQIDNAKLASDDFRT---KY-ET
EMSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSAQLSQVQSLITNVES--------------------------
QLAEILCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCTTT----------NACDKSIGPCISNPC----------------------------
-----------------GPR-A-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDAKGCTT-TNSPS---------------
------------------------------------------TPCQNCSRITNVSTIS-S
-N------------NRCHP-G--G------LKVNNC-QPAGYILRTPRDRGCQPTPCF--
------CRKPI--------------YLMNN-----FD----A-----------RSSLDDC
SWYG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVRMLERENA--ELESKIQ-EESNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLKQILNVLTLGK--ADLEAQVQSLKEE
-LLCLKNNHKEEINSLQC--QLGERL--DIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCQYESI----METNR----KDVEQWFNTQI--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEVE--LQA------------QHRM--RD-
-----SQECILTETEARYTALLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDIK---SRLECEITTYRSLLESLD---G------K---RP
CYPCATK----------CEPSP-WTSCKSGAM------------------------ESTA
P--ACTS---------SAH--CGLKEHCNACGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSSRGN-NSSRGSLKSC----------
------------------------------------------------LKPSGRRAV---
--SI-----------TGHSGASAPKFPFP-----YRANSYQSSQS---TPLGHLRP--NT
RCH--SM-----------------------------------SSLPG-AH-NIPANVGTC
SWFG---DIALNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMRFLND---
-------------------------RLANY-LE-KVRRLEREKA--ELEGKLQ-EWSQCQ
VPN--ICSNYTTYFKTIDELQR--KLLCSKSENSRLVVQVDNAKLAADDFKT-------S
ELYLRKIVETDIN-------------------SLHRNLDDLSLAK--CELESQVESLKEE
-MLCLKKNHEQEVHNLQC--QLGDKL--RFELDTDP------------------------
---------------------------------------------------PGDLNRVLG
EMRCQYEAM----VKTNQ----NDVEQWFIAQS--------------------EGISLK-
-AMS---CSEELQCCQ-SEILELKR-SVNALEVE--LQA------------QHKM--RD-
-----CLENSLTESEARYSTELAQMQYLISNVEE--------------------------
QLAEIRADLERQNQEYQVLLDVK---ARLVCEISTYRNLLERED---S------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------VPFHILQGNQQ----------------GEKGISRK
FRLC----L----------QPG---THSLPPST---------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---S-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKSNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----REVEQWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CN---------LP
SNPCATT----------NACSKPIGPCLSNPC------------------------T---
------PCVPPAPCTPCAPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSTCCV-TSNLQASLKSCP--
------------------------RPASVCSGSVNC-RPELCLGYVYQPMACLPSVCMPT
TFWPASCVSKT--------------YLSSSR-----W---PAS--------GISSAMGPG
SWYS---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LA-RVRELERENA--ELESRIQ-EASHSQ
VLT--MTPDYQSHFRTIEELQQK--ILCTKAENSRMVVNIDNAKLAADDFRA---KY-EA
ELAMRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVSSLRC--QLGDCL--NIEVDAAP------------------------
---------------------------------------------------PVDLNRVLE
EMRCQYETM----VEANR----RDVEEWFNMQM--------------------EELNQQ-
-VAT---SSEQLQNYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLTESEARYSSQLAQMQCMITNMEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLESEINTYRSLLESED---I---------KLP
GNPCSTP----------SCTPCAPSP----------------------------------
----------CVSRTVCVPH--TICVPCLPCPQ-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCP----PA-----
----PSC-RTS--------------CASRPCVPPSCH---G-CTLPG-AC-NIPANVGSC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENC--ELERRIQ-ERSQQQ
EPS--LCPSYQSYFRTIEELQQK--ILCNKAENARLAVEVDNAKLATDDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEEEVNTLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSLYEAL----VETNR----REVEEWYTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLNESEARYSSQLSQVQCLIGSVES--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLDSED---CK---------LP
CNPCATT----------NACNKPTGPCVANPC------------------------T---
------PCPPPAPCTPCIPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LGC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDIGCQPGAE-ANIAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---ENTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELEATLL-ERSKCH
EST--VCPDYQSYFHTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADKC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----LETNR----QDVEQWFQAQS--------------------EGISLQ-
-DMS---CSEELQCCQ-SEILELRC-TVNALEVE--R------------QAQHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---TRLENEIATYRNLLESED---C------K---LP
CNPCSTS----------PSCVT----AP-----------------------------CA-
---PRPSC---------GP--CTTCGPTC-GASTTGSRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------T---------MPYNCCL----SN-----
----MSC-RST--------------CSSRPCVPPSCH---S-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRKLERENA--ELESLIQ-ERCQPQ
EPL--LCPSYQSYFRTIEELQQK--ILCGKSENARLVVQIDNAKLAADDFRT---KY-ET
ERSLRQLVESDIN-------------------SLRRVLDELTLCK--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCMITNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---C------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKAGFSSG-SLKSPGGA
-------------------SGGSTRVSAMY-SSSSC-KLPSLSRGARSFSAC--------
--------SAG--------------LGRSSYRATSCL---PTLCLPA-GGFTTSYSV-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLEQDNA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFRTIEELQKK--TLCSKAENARLVVEIDNAKLAADDFRT---KY-ET
EVSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFDTQT--------------------EELNQQ-
-VVS---SSEQVQSCQ-AEIIELRR-TVNTLEIE--LQA------------QHSM--RD-
-----ALESTLAETEARYSSQLAQMQCMITNVET--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
CNSCAPD----------CSPSKSCLPCLPAA-----------------------------
------SCGPSAARLTCSPR-----PICVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------SLTPSSA---------MSYSCFL----PS-----
----LSC-RST--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGSC
GLFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-ERCQQQ
EPE--VCPNYQSYFRTIEELQQK--ILVSKSENARLVVQIDNAKLAADDFRT---KY-ET
ELGLRQLVESDIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKQNHEQEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----RDVEEWFTTQT--------------------EELNRQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLSQVQGLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLESEINTYRGLLESED---CK---------LP
CNPCATT----------NACDTSIGSCVSNPC----------------------------
-----------------VPR-T-RCGP----------------CN--------TFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PN-----
----LSC-RST--------------CSSRPCVPPSCH---T-CTLPG-AC-NIPANVGNC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-EWCQQQ
VPF--VCPSYQSYFRTIEELQQK--ILCNKSENARLVVQIDNAKLASDDFRT---KY-ET
EVGLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLSLKQNHEQEVNILRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----RDVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLNQVQCMITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVSNPC------------------------A---
------------------QR-A-WCGP----------------CN--------TFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSCISL-PCS----LGC----------
------------------------------------------------PKPLGARSV---
--PVPVPV----VEVECPTR-------PECLLANLAHANRVRVGS---TPLGRPSLCLPP
TCQA-AC------------------------------------TLPG-TR-HIPGNIGIC
GSYC---EGSLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMRFLND---
-------------------------RLANY-LE-KVRQLERDNA--DLEAKLR-EWTRCH
ESS--VCPDYQSYFRTIEEFQQ--KILCSKAENTRLIVQIDNAKLAADDFRI---KH-ES
ERALRQLVEADMC-------------------GMQKLLDDATLAK--ADLEAQQESLKEE
-QLALKSNHEQEVKILRS--QLGDKI--RIELDTEP------------------------
---------------------------------------------------TVDFSRVLG
EMRCQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQA------------QHTL--KD-
-----CLQNSLCEAEARYGTELAQMQSLIGNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLEDEINTYRKLLECED---C------K---LP
CNPCSTP----------PSCVP----AA-----------------------------CA-
---PRPSC---------AP--RTVCGPASVCGAGTGSRF---------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKSC-ATTTSSS---------------
------------------------------------------TSCQNCSRTTNVIN---S
-S------------NTCHR-G--G------LKANSC-R----VLRTVQVLGCQPTPCF--
------CRRPI--------------YLVNN-----FS----A-----------CPSLDDW
DCCG---EGI-NSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1068)

EKE---------------------------------TMQILND---
-------------------------RLANY-LE-KVRVLEQENA--QLEGKIQ-EECSRE
LPV--LCPDYLSYYSTIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---KY-EA
EVSLRQPVEADAN-------------------SLRQILNALTLAK--ADLEARVQSLKEE
-LLCLKSNHEEEVNSLQS--QLGDRL--NIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCQYESI----METNR----KDVEQWFNAQM--------------------EELNQE-
-VVT---SSQQQQCCQ-KEIIELRR-TRNALEVE--LQA------------QHRM--RD-
-----SQECMLTETEARYAALLAQIQSLIDNLEV--------------------------
QLAEIRSALEGQNQEYEILLDVK---SRLEGEIATYRSLLESSD---C------E---LP
WNPCATE----------CESPM-HTSCKAR-----------------------------A
P--AYTS---------SVP--QGIRKAYSACAP--LSRILVKICT----------IT--Q
EIQDGKIISSHEHVQ--------PCYITRLARV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTEGCTA-TTSSS---------------
------------------------------------------TSPPNCSGNTNFKIIS-L
-K------------KSCHHT-------------NRR-QTPSGVVRNPLGRGCPPTPCL--
------GHIPI--------------YLIRN-----HS----G-----------GPSLDDC
S--------I-NSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1064)

EKE---------------------------------TMRILND---
-------------------------RLANY-LE-KVRMLERENG--ELERRIQ-EECSKE
PPD--PCPDYQSYYATVEQLQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---NY-EA
EVSLRQLVEADAN-------------------GLQQILDVLTLSK--ADLEARVQSLKEE
-LLCLKTNHEQEINSLQG--QLGDRI--NIEVTAAP------------------------
---------------------------------------------------AVDLNEILQ
QMRCQYESI----METNR----KDVEQWFNTQM--------------------EELNEQ-
-VAT---SSQQQQCFQ-KEVIELRR-TMSALEVE--LQA------------QHRM--RD-
-----SQESILTETEARYATLLAQTQSLIHNLEA--------------------------
QLAEIRGALQKQNQEYEVLLDLK---SRLECEIATYRGLLESSD---D------T---LP
CNPCATR----------CTP------CTAGAM------------------------EHAV
A--GHSS---------SVL--PATHKPCSASGL--PSQILVKIHT----------IT--K
EIKDGKVISSYEHVQ--------PCYIPRSTKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SVHRSLSSSSQGPV---LGMSGS
VYRKGG----------VQRTG----GAPSVYGGAGGQGTRISI-SR--STVS--------
--SG---SDLLAG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

DEKR---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRSLEQSNL--QLEAHIK-QWYETN
APS--AVRDYGRYYAQIKELQDQ--IKDAQIQNARCVLQIDNAKLAAEDFRL---KF-ET
ERGIRLTVEADLQ-------------------GLNKVFDDLTLHK--TDLEIQIEELNKD
-LAVLKKEHQEEVDVLRR--QLGNTV--NVEVDAAP------------------------
---------------------------------------------------GLNLGDIMN
EMRQKYEVL----AQKNL----QEAKEQFERQS--------------------ETLQQQ-
-VMV---NNEELKGTE-AQVTELRR-TCQSLEIE--LQS------------HLSM--KD-
-----SLEHTLEDTKARYANQLATIQGVLSSLEA--------------------------
QLMQVRSDMERQNNEYNALLDIK---TRLEQEIATYRRLLEGED---VK---------S-
------TQ---------YQLST--------------------------------------
-----------------------------LEER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EESI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------PSDSSPTCCSSESGARASD--
-----------------------HPSV-SCSGETSS-PPSACATSRC-------------
-------QTPT--------------FLPRSHLSTGCL---TPCYFAG-SC-NIPCLLGTS
AWCE---DGVFNSNEKX---------------------------------XXXXXXX---
-------------------------XXXXX-XX-XXXXXXXXXX--XXXXXXX-XXXXXX
XXX--XXXX

PF00038 // ENSGT00900000140814_1_Domain_1 (610, 955)

XXXXXXXXXXXXXX--ILCTKAENSRLAVQLDNCKLAADDFRS---KY-ES
ELSLHQLVETDID-------------------SLRRILDELTLCK--SDLEASVESLKDD
-LFCLKKSHEEEVNLLRG--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TVDLNSVLD
EMRCRYETV----LASNR----RDAEEWFAAQT--------------------EELNQQ-
-QLS---SAEQLQGCQ-TEILELKR-TANALEIE--LQA------------QQNL-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKTSFSSA-SLKGLGGA
-------------------GGGSTRVSAMY-SSSSC-KLPSLSRGARSFSAC--------
--------SVG--------------LGRSSCRAASCL---PALCLPS-GGFATSYSL-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-EWCQQQ
VPY--LCPDYQSYFRTIEELQKK--TLGTKAENARLVVQIDNAKLAADDFRT---KY-ET
ELSMRQLVESDMN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEEWFNTQT--------------------EELNQQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNGLEIE--LQA------------QQSM--RD-
-----ALESTLAETEGRYGSQLAQMQHLIGNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRGLLESEE---G---------KLP
CNPCAPD----------HSPTKSCLPCLPAV-----------------------------
------SCSPAAVRTTCSPR-----PICVPGPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PT-----
----MSC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 731)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEQRIQ-ERNQQQ
DPL--VCPAYQSYFRTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEE-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACGKPIGPCV-SN-----------------------------
---PCAPCPPPAPCTPCVPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSTGSA-KGLCGT
-------------------VGSFSRMSSIH-SMGSY-RAPSLVGTV----------GSMP
SFRT------------------------GFSGLGGCL---PGSYLSS-GC-HSSGFAGSG
GWFC---EGTFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKA---------------------------------TMQVLND---
-------------------------RLANY-LE-KVRQLEQENA--SLECRIR-EWYECQ
VPY--ICPDYQSYFKTAEDLQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNVLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYETL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VLS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYGSQLGQMQCLITNVES--------------------------
QLTEIRCDLERQNHEYQVLLDVK---ARLESEIATYRHLLEGED---C---------KLP
AHPCSTE----------CKPAVRVPYISS-------------------------------
--------TP------CTLA-----GPCTPAPQ-----VSTQIRT----------IT--E
EIRDGRVVSSREHVV--------PRAL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MP----LVC----------
------------------------------------------------TMAPGSNEI---
--LC----------LSIDPRAEANFLAKMCLCRQRGHANRVRVGS---TSPGPPQPLSAP
TFSHSGF-----------------------------------VLCQG-PV-TFPAHWK-L
WAYA---KTPCNGHEKE---------------------------------TMQFPER---
-------------------------PGWPTPGE-GCRPAGAGNARAGEPHFPR-GASKCH
EST--G------------SLQQ--K--V

PF00038 // ENSGT00900000140814_1_Domain_1 (629, 1075)

SKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADQC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQA------------QHTL--KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------ASCTS----C---------------------------------
-----PSC---------GP--VTG-GSASGHGASMGR-----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------CQPPPTNK----------------GIKGLRRK
ERLKPHH-I----------HLYRLTCSITSPCT---------MPYNCCL----PN-----
----LSC-RST--------------CSSRPCVPPSCH---T-CTLPG-AC-NIPANVGNC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-EWCQQQ
VPF--VCPSYQSYFRTIEELQQK--ILCAKSENARLVVQIDNAKLASDDFRT---KY-HT
ELGLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLREE
-LLSLKSNHEEEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----RDVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLAQVQCLISNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACGNS-------------------------------------
----CGSC-GKCQ--------T-RC-----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SFHRSLSNSLQASV---VS----
---TVG----------TQRLG----MTPSVYGGAGGRGIRISN-SR--HTVNYGSDLT--
--GG---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKM---------------------------------AMQNLND---
-------------------------RLASY-LE-KVRTLEQSNS--RLEVQIK-QWYETN
APR--AGRDYSAYYKQIEELRNQ--IKDAQLQNARCVLQIDNAKLAAEDFRL---KY-ET
ERGIRLTVEADFQ-------------------GLNKVFDDLTLHK--TDLEIQIEELNKD
-LALLKKEHQEEVDGLYK--HLGNTV--NVEVDAAP------------------------
---------------------------------------------------GLNLGAIMN
EMRQKYEVM----AQKNL----QEAKEQFERQT--------------------EVLQQQ-
-VIV---NTEELKGTE-VELTELRR-TSQSLEID--LQS------------HLSM--KE-
-----SLEHTLEETKARYSSQLANLQSLLSSLEA--------------------------
QLMQIRSDMERQNNEYHILLDIK---TRLEQEIATYRRLLEGED---VR---------T-
------TE---------YQLST--------------------------------------
-----------------------------LEER--DIKKTRKIKT----------VV--Q
EVVDGKVVSSEVKEV-EENI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGCTT-TNSPS---------------
------------------------------------------TPCQNCSRITNVSTIS-S
-N------------NRCHP-G--G------LKVKNC-QPAGHTLRTTRDQGCQPTPCF--
------CRKPI--------------YLINN-----FI----V-----------RSSLDDC
SWYG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVRMLERENA--ELESKIQ-EENNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLKQILNVLTLGK--ADLEAQVQSLKEE
-LICLKNNHKEEINSLQC--QLGERL--HIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCQYESI----METNR----KDAEQWFNTQI--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEVE--LQA------------QHRM--RD-
-----SQECILTETEARYTTLLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEITTYRSLLESWD---G------K---RP
CYPCATK----------CEPSP-WTSYKSGAM------------------------ECTA
P--VCTS---------SAP--CGLKEHCSACGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTTNSCQS-TFSSSVS-------------
-------------------------------------------------LKSYYRVPISK
-----PVS----TSFSCHPGD---------FEHGDC-RPTGCVSSTCQPGECPPTLCLPS
PQ-----WTSS--------------HLTSS-----CN----P-----------PSHLRSC
GWYG---EGYFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMQSLNA---
-------------------------RLASY-LD-KVRCLEQENA--NLECKIQ-EFCQNQ
APA--VCPDYLAYFRMIEELQQK--ILCTKAENSRLVTQIDNTQLASDDFRT---KY-KV
ELSLRQLVEADIN-------------------GLQRILGKLILCK--ADLEMQVESLKEE
-LLCLRNNHTEEVNSLQC--QLGNRL--NIQVDIAP------------------------
---------------------------------------------------SVDLNQALE
KMRCQYESL----LETNR----RDIQEWFNTQR--------------------EELNQQ-
-MAF---SSGQLQCCQ-SESIELRR-TVNALEIE--LEA------------QHSL--RN-
-----SQENILTEVKARYSSQLAQVQALIDNVEF--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLEGEISTYRSLLESED---C------K---LP
SNPCARE----------STVST-CPPCKPCAI------------------------ECTA
P--TQAACEPCNLCAPPAS--LGKCMPCKTCTP--APRIIVKIFT----------II--E
EIRDGKVISTQKLVQ--------PCVFYNPQFQ-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSACS-SSCSPESCCRAT---
----------------------------------DC-PSV--------STCSTDIPCLPA
TCGAARCQTPR--------------FLCRSRLSSSCY---LP-------------VVGHC
GWRD---EWAFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-RVRCLEVENA--ELECKIR-EQCEQQ
IPF--VCPDYQCYFNTVENLQQK--ILCTKAENSRLAVQIDNCKLAADDFRT---KY-EA
ELSLRRPVEADVG-------------------GLRRILDDLTLCK--SDLEAQLESLKED
-LLCLKKNHEEEVNALQA--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TVDLNKLLD
EMRCQYENV----VANNR----REAEEWFAVQT--------------------EELNQQ-
-QLS---SAEELHCCQ-SEIIELDR-TANALEIE--LEA------------QESL--KE-
-----SLECTLSETEDRYSSQLAQMQCLIDNVEI--------------------------
QLAEIRCDLERQNQEYQILLDVK---ARLECEIATYQSLLENED---C---------KLP
CNPCSAP----------NA--------SCTF-----------------------------
-------CDLSEPFVICTV--ENCQA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------RLAAKPPPTIK----------------SIKGPGRK
GRLTLTHI----------YLHPLTCPSISPTHT---------MPYNCCL----PN-----
----MSC-HSS--------------CSSRPCIPPSCH----GCTLPG-AC-NIPANIGSC
GWFC---EGSFNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLECENA--ELE-RIQ-EWCQQQ
--Y--VCPNYQ-YFRTIEELQQK--ILCAKSENTRLVVQIDNAKLASDDFRT---KY-EM
ERCSRQLVESDIN-------------------SLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNTLRC--QIGDRL--NIEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----RDVEEWFTTQS--------------------EELNKQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLGQVQCMITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRCLLEGED---C------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGCTT-TNSPS---------------
------------------------------------------TPCQNCSRITNASIIS-S
-N------------NRCHP-G--G------LKVNNC-QPAGHVLRTPWDQGCQPTPCF--
------CRKPI--------------YLMNN-----FN----T-----------RSSLDDC
SWYG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1062)

NEKE---------------------------------TMQILNE---
-------------------------HLANY-LE-KVRMLERENA--ELESKIQ-EESNKE
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLTADDLRA---KY-EA
EVSLRQLVEADAN-------------------GLKQILNVLTLGK--TDLEAQVQSLKEE
-LLCLKNNHKEEINSLQC--QLGERL--DIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCQYESI----METNR----KDVEQWFNTQI--------------------EELNQQ-
-VVT---SSQQQQCCQ-KEIIELRR-TVNTLEVE--LQA------------QHRM--RD-
-----SQECILTETEARYTALLTQIQSLIDNLEA--------------------------
QLAEIRCALERQNQEYEILLDVK---SRLECEITTYRSLLESLD---G------K---CP
CYPCATK----------CEPSP-WASCKSGAI------------------------ESKA
P--ACTS---------SSP--CSLKEHCSACGP--LSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCFIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------S-LLGLWVVFLCWPTACR-------
--------PPP--------------VSPRA-----TC----PAPGPA-AR-STSGSMGSY
TRHY---EVSYPQ

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

NDRE---------------------------------TLQFLND---
-------------------------RLASY-LD-RVRQLERENE--EVERRLQ-EAN-QQ
PQA-GKSNGYQSYFRVIEELQQKVRILLTKADNTRMLVHIDNAKLAADDFRT---KY-QS
ELSLRQVVEWDIH-------------------GLRRILDDLTLCK--AGLEAQVESLKEE
-LLSLKKSHEEEVAQLQS--QLGDRL--NIEVAAAP------------------------
---------------------------------------------------PVDLTRVLE
EMRHQYEAV----VETNR----RDAEQWFSTQM--------------------EELNQQ-
-VAT---SSAQLQNYQ-EDIIDLKR-SANILEIE--LQA------------QNSL--RD-
-----SLENTLNETKARYGSQLAQMQGLIGSVES--------------------------
QLVEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLDSED---F------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYTCCL----PA-----
----LSC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 954)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRELERENA--ELERRIQ-ERSQQQ
EPL--LCPSYQSYFRTIEELQQK--ILCAKSENNRLMVQIDNAKLAADDFRT---KY-DT
ELSLRQLVEADIN-------------------SLRRILDELTLCK--SDLEAQVESLREE
-LLSLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------SVDLNRVLN
EVRSTYEAV----VETNR----REVEEWYTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--VR-
-----GR-----------------------------------------------------
----WGWGSPRQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NASGSSCGPCGSYAP------------------------SH-R
H--RF--------------P-S-PCTP----------------RL--------SFCT--S
DSLCSI----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSTGSA-RGLCGT
-------------------TSSFSRMSSIH-SMGSC-RAPSLVGTV----------GPMS
SFRT------------------------GFSGLGGCL---PGPYLSS-GC-HSSGFAGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKA---------------------------------TMQVLND---
-------------------------RLANY-LE-KVRQLEQDNA--QLECRIR-EWYECQ
VPY--ICPDYQSYFKTAEDLQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCR--ADLEAQVESLKEE
-LLCLKKNHEEEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYETL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VLS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QQSM--RN-
-----SLESTLAETEARYGSQLAQMQCLITNVES--------------------------
QLAEIRCDLERQNHEYQVLLDVK---ARLESEIATYRCLLEGED---C---------KLP
AHPCSTE----------CKPVVRVPYTPS-------------------------------
--------TP------CTPA-----GPCTPAPQ-----VSTQIRT----------IT--E
EIRDGRVVSSREHVV--------PRAL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MASKCIKS-SFS-----------------
-----------------------------------------SASLKSPGGAPGG------
------------------------------------------------------STCVST
MYSSGSCKLPSPSRRTRSFSACSTGLSRSSCRATSF----LPALCH--HIFATGY-SMGG
GWFG---EGILTS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENT--ELESRIR-EWCQQQ
VPY--MCPNYQSYFQTIEELRKK--TLCTKAENARLVVQIDNAKLAADDFRT---KY-EM
ELSMRQLVEADIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKTHEEXXXXXXX--XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX-------
---------------------------------------------------XXXXXXXXX
XXXXXXXXX----XXXXX----XXXXXXXXXXX--------------------XXXXXX-
-XXX--------------XXX--XX-X------------------------XXXX--XX-
-----XX---X--X-XXXX-XXXXXXXXXX--------------XXXXXXXXXXXXXXXX
XXXXXXXXXXWWNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CHPCAP-D---------YSPSKSCLP--CP------------------------------
---PVASCSPGTARTTCSP--RAICVPCPGS-----RF----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MY-SSSSC-KLPSLSRGARSFSAC--------
--------SAG--------------WGRSSCRAASCL---PALCLPS-AGLATSYSL-GG
GWYG---EGILTV

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQVLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIR-EWCEQQ
VPY--LCPDYQSYFRTIEELQKK--ALCSKSENARLVVQIDNAKLAADDFRT---KY-EM
ELSMRQLVESDMN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWFNTQT--------------------EELNQQ-
-VVS---SSEQLQTCQ-AEIIELRR-TVNALEIE--LQA------------QQSM--RD-
-----SLENTLTETEARYSSQLSQVQCMITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---C---------KLP
CHPCTPD----------QLPSKSCLPCLPAA-----------------------------
------TCSPGAARTTCSPR-----PTCVPCPR-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------RRLGF-IP----------------ETR-----
----------------NQILKLIFRALT--------------MPYNFCM----PN-----
----LSC-RTS--------------CTSRPCIPPSCH----SCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIQ-ERNQQQ
DPL--VCPAYQSYFRTIEELQQK--ILCSKSENARLVVQTDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTTQVGIEVQRQQLTLSLPLLLLQTEELNKQ-
-VVS---SSEQLQSYQ-R----------------------------------------N-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLSEIRSDLERQNQEYQVLLDVK---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVINP--------------------------C-A
T------------------R-S-RCGP----------------CN--------TFGH---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSYSCGL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--VCASYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLASDDFRT---KY-ET
EMSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQLQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACDKSTGPCISNPC----------------------------
-----------------GPR-A-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYTCCL----PA-----
----LSC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 987)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRELERENA--ELERRIQ-ERNQQQ
EPL--LCASYQSYFRTIEELQQK--ILCNKAENARLVVQIDNAKLAADDFRT---KY-DT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEEQ------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------LAQVQQLISSVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACGKPIGPCV-AN-----------------------------
---PCTPCPPPAPCTPCVPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSTYVSS-SHP----LCS----------
------------------------------------------------TKVPGASNI---
--P--ISS----INVRGRPGTQ-AKCASLCFLANLAHAN-VGLGS---TSLGRPSLCLSP
SCHT-AC------------------------------------PLPG-TR-HILGSNGSC
TTYG---EGTLNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 731)

HEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVWQLERENA--ELETKIW-DSKCEG
KSN--VCPDYQSCFRTIEELQQ--KVLCSKAENARLIMQVDSAKLAADGFQI---KH-EN
EHALSQLVEADMC-------------------GMHKLLDDLSLAK--AGLEVQVESPKEE
-QLCLKSNHEQ-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGSTV-TISSS---------------
------------------------------------------AAPQNCSGNTDFRTSS-S
-N------------NSCCHS---------------G-QSTGHAQRTPQGQGCRPTPCL--
------YRTPN--------------YLIRT-----YN----F-----------HPCLEDC
SLCG---EGI-NSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1063)

EKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVRMLEGENS--ELEDKIQ-EECSKV
LPV--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---NY-EA
ELSLRQLIEADAK-------------------GLKQILDVLTLSK--ADLEARVQSLTEE
-LLCLKTNHEEEINSLQC--QLGDRI--NIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
EMRCRYESI----VETNR----KDVEQWFDTQM--------------------EELNQQ-
-VVT---SSQQQQCYQ-KDVIELRR-ARSALEVE--LQA------------QHRM--RD-
-----SQECILTETEARYTTLLAQIQGLIHNLEA--------------------------
QVSDIRGALERQNQEYQVLLDIK---SRLECEIATYRSLLESLD---G------R---LP
CNPCATK----------CEPS-----YQAGAM------------------------ECFA
P--IYTS---------SSL--PWIHKPCSASGP--PSRILVKICT----------IT--K
EIKDGKVISSHEHVQ--------PCYIIRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MTTCSRQ-FTSSSSMKGS----------
-------CG------------------------------IGGGIGGGSSRISSVLAG---
--------------GSCRAP------STYGGGLSVS-SSRFSSGGACGLGGGYGGGFSSS
SSFGSGFGGGY--------------GGG---LGAGFG-------GGL-GA-GFGGGLGGG
FAGG---DGLLVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

SEKV---------------------------------TMQNLND---
-------------------------RLASY-LD-KVRALEEANA--DLEVKIR-DWYQRQ
RPT--EIKDYSPYFKTIEDLRNK--IIAATIENAQPILQIDNARLAADDFRT---KY-EH
ELALRQTVEADVN-------------------GLRRVLDELTLAR--TDLEMQIEGLKEE
-LAYLKKNHEEEMLALRG--QTGGDV--NVEMDAAP------------------------
---------------------------------------------------GVDLSRILN
EMRDQYEQM----AEKNR----RDAEAWFLSKT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-RVNTLEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRRLLEGED---C------K---LP
PPPCAMA----------CKPAIR------------------------------------V
PSVPPVP---CAPAVPCTS-A---------------PQVGTQIRT----------IT--E
EIRDGKVISSREHVQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------METKGSTV-TISSS---------------
------------------------------------------TAPQNSSGDTNFRISS-S
-N------------NNCCPD---------------S-QPTGLTQRTPQSRGCGPTPCL--
------YRTAN--------------YLIRP-----YH----F-----------HPCLEDY
SWCS---EGI-NSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1062)

EKE---------------------------------TMQTLNE---
-------------------------RLASY-LE-KVRMLEGENS--ELENKIQ-EECSKA
LPV--LCSDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---NY-EA
ELSLRQLVETDAN-------------------GLRQILDVLTLSK--TDKEARVQSLTEE
-LLCLKTNHEEEINSLQC--QLGDRI--NIEVTAAP------------------------
---------------------------------------------------SIDLNKILQ
EMRCRYESI----VETNR----KDIEQWFNTQM--------------------EELNQQ-
-VIT---SSQQQQCCQ-KDLIELRR-TMSSLEVE--LQA------------QHRM--RD-
-----SQECILTETEARYTTLLAQIQGLIHNLEA--------------------------
QVADIRSALERQNQEYEVLLDTK---SRLECEIATYRSLLENLD---G------R---LP
CNPCATK----------CEPS-----FQARAV------------------------EYFT
P--VYTS---------SSL--PEIHKPCSASGP--PSRILVKICT----------IT--K
EIKDGKVISSHEHVQ--------PCYITRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSMGSV-KGLCGT
-------------------AGGISRVSSTR-SVGSC-RVPSLAGAA----------GCIS
SVRS------------------------GLSSLGSCS---LGSYLSA-GC-HPSGFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-EWYESQ
IPY--ACPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--ADLETQVESLKEE
-LLCLKKNHEEEVSALRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRILE
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYGSQLAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEITTYRRLLEGED---C---------KLP
PPPCAMA----------CKPAIRVPSVPS-------------------------------
--------APCAPA-----------VACIPAPQ-----VGTQIRT----------IT--E
EIRDGRVISSRENLQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-RTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NAYEKSTGSCVTNAC----------------------------
-----------------GPR-S-RCGP----------------CN--------TFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSGR-----------------SFHRSLSSSSQDPA---LSMSGS
LYRKGT----------VQRLG----AAPSVYGGAGGHGTRI---SK--AVVSYGGDLS--
--NG---VDLFGG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NGKL---------------------------------AMQNLND---
-------------------------RLANY-LE-KVRSLEQSNS--RLEVQIK-QWYDTN
APS--TIRDYSSYYTQIMELQKQ--VKDAQVQNAQCVLRIDNAKLAAEDFRL---KF-ET
ERGMRVTVEADLQ-------------------SLSKVYDNLTLQR--TDLEIQIEELNKD
-LALLKKEHQEEVEVLRR--QLGNNV--NVEVDAAP------------------------
---------------------------------------------------GLNLGEIMN
EMRQKYEVL----AQKNL----QEAKEQFERQS--------------------QALQQE-
-VTV---NMEELKGFE-VQVTELRR-TYQTLEIE--LQS------------HLSM--KE-
-----SLERSLEDVKARYASQLAVIQEMLSSLEA--------------------------
QLMQIRSDTERQNQEHNVLLDIK---TRLEQEIATYRRLLEGED---IK---------T-
------TE---------YQLST--------------------------------------
-----------------------------LETK--DIKKTRKIKT----------VV--E
EVVDGKVVSSEVKEI-EESV--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MACNCL----PN-----
----LSC-RTS--------------CASRPCIPHSCH----SCTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 652)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIQ-ERNQQQ
DPL--VCPAYQSYFRTIEELQQK--ILCAKSENSRLLVQVDNAKLASDDFRT--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-TRCQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNSLEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLSEIRSDLERQNQEYQVLLDVR---SRLECEINTYRGLLESED---CK---------LP
CNPCATT----------NASGNSCGS---CQK------------------------RC-C
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSTGSA-KGLCGT
-------------------VGSFSRMSSIH-SMGSY-RAPSLVGTV----------GSMP
SFRT------------------------GFSGLGGCL---PGSYLSS-GC-HSSGFAGSG
GWFC---EGTFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKA---------------------------------TMQVLND---
-------------------------RLANY-LE-KVRQLEQENA--SLECRIR-EWYECQ
VPY--ICPDYQSYFKTAEDLQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LL---------FNVLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
DMRCQYETL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VLS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYGSQLGQMQCLITNVES--------------------------
QLTEIRCDLERQNHEYQVLLDVK---ARLESEIATYRHLLEGED---C---------KLP
AHPCSTE----------CKPAVRVPYISS-------------------------------
--------TP------CTLA-----GPCTPAPQ-----VSTQIRT----------IT--E
EIRDGRVVSSREHVV--------PRAL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------Q-

PF00038 // ENSGT00900000140814_1_Domain_1 (625, 1026)

-ILCSKSEDARLLVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQVESLREE
-LLCLKQNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VDTNR----REVEEWFTRQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLAQVQCMVTNVEA--------------------------
QLAEIR------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSACCV-TNNLQASLKSCP--
------------------------RPASICSSSVNC-RPELCLGYVCQPMACLPSVCMPT
TFRPASCLSKT--------------YLSSSR-----W---AAS--------GISSSTGPG
SWYR---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TLQFLNE---
-------------------------RLASY-LT-RVRQLEQENA--ELESRIQ-EASHSQ
VLT--TTPDYQSHFRTIEELQQK--ILCTKAENARMVVNIDNAKLAADDFRA---KY-EA
ELAMRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVGSLRC--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRVLE
EMRCQYETM----VEANR----RDVEEWFNMQM--------------------EELNQQ-
-VAT---SSEQLQNYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLTESEARYSSQLAQMQYMITNVEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLESEINTYRSLLESED---S---------KLP
CNPCSTP----------SCTPCAPS-----------------------------------
---------QCVPRTVCVPR--IVGVPCSPCPQ-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MLYAKPPPTIN----------------GIKGPQRK
ERLKPAHI----------HLQQLTCFSITCSST---------MSYSCCL----PS-----
----LGC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVHQLERDNA--ELEKLIQ-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCAKAENARLVVNIDNAKLASDDFRS---KY-QT
EQSLRRLVESDIN-------------------SIRRILDELTLCK--SDLESQVESLREE
-LICLKKNHEEEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSAQLSQVQRLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CNPCATT----------NASGNFCGPCVILSS------------------------QP-V
----CCSCLAIIYTYSSL-K-I-HLH----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQTCTPTFSTGSV-KGLCGT
-------------------AGGISRVSSIH-SVGSC-RVPSLAGAA----------GYIS
SARS------------------------GLSGLGSCL---PGSYLSS-GC-HSSGFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWYESQ
IPY--ICPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVSVLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILE
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNSLEIE--LQA------------QHSM--RN-
-----SLESTLVETEARYSSQLAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRRLLEGED---C---------KLP
SPPCAMA----------CKPAIRVPSVPL-------------------------------
--------VPCAPA-----------VPCTSAPQ-----VGTQIRT----------IT--E
EIRDGKVISSREHVQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------KDFSRR-----------------SFHQSLSLSTQGPS---LSPS--
---VRS----------MPPLW----AAPSVYGGAGGYGTRIST-SR--STASSHSI----
PTSV---GGLLNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKT---------------------------------TMQNLND---
-------------------------RLASY-LE-KVRFLDQSNS--KLEAQIK-QWYETK
APS--SGRDYSAYYKQIQELQNQ--IKDAQLHNARCVLQIDNTKLAVEDFRL---KY-ET
ERAMHLTLKVDLQ-------------------SLSKVFDDLTLHK--TDLELQIEELNRD
-LAVLKKEHKEEVDGLQR--HLGNTV--NVEVDVAP------------------------
---------------------------------------------------GLNLSAIIN
EMRQKYEVM----AQEYI----QKAKEQFEMQI--------------------EDLQQE-
-VTV---STEELKETE-AQLKKLRN-TSQSLEIE--LQS------------CYSV--KT-
-----SLEHTLEETNVAYSGQLANLQARLNAVED--------------------------
ELMQVRGDAERQKAEYLTLLDVK---IRLEQEIATYRRLLEGED---VK---------KR
--KNRMTE---------YQLNT--------------------------------------
-----------------------------LEEK--DVKKTRKIKT----------LVQVQ
EVVDGKVVSSTVKEI-KEMEENI-----------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSSYSSS-SCP----LVC----------
------------------------------------------------TMAPGARNV---
--S--VSP----IDVGCQPGAE-ANVAPMCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHS-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYG---KNTLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEATLL-ERSKCH
EST--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KL-ES
ERSLRQLVEADQC-------------------GTQKLLDDATLAK--ADLEAQQESLKEE
-QLSLKSNHEQEVKILRS--QLGEKL--RIELDIEP------------------------
---------------------------------------------------TIDLNRVLG
EMRAQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-TVNALEVE--RQ----------AQHTL----KD-
-----CLQNSLCEAEDRFGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---LP
CNPCSTP----------ASC--------------------------------------T-
---SCPSC---------GP--VTGGSASG-HGASMGR-----------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PA-----
----MSC-RTS--------------CSSRPCVPPSCH----GCTLPG-AC-NIPANVGNC
NWI---------------------------------------------------------
---------------------------------------------------

PF00038 // ENSGT00900000140814_1_Domain_1 (592, 869)

-Q-ERNQQQ
DPL--VCPAYQAYFRTIEELQQK--ILCGKSENGRLVVQIDNAKLAADDFRT---KY-ES
ELSLRQLVESDLN-------------------GLRRILDELTLCK--SDLEAQVESLRQE
-LLCLKQNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWL-------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------P
CNPCATT----------NACDKPIGPCVTNP--------------------------C-V
T------------------R-S-RCGP----------------CN--------SFGC---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGCTT-TIASS---------------
------------------------------------------TPCQNCSRITNFRTIS-S
-N------------NSCHR-G--G------LEANSC-QPPGHVLRMPQDQGCQPTPCF--
------CRMPT--------------YIIRN-----LN----A-----------CLSPDDC
GWYG---EGI-NSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1068)

EKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVRMLEKENT--ELECKIQ-EECTKE
LPV--LCPDYQSYYRAIEELQQK--ILCTKAENSRMVSQIDNTKLAADDLRA---KY-EA
EVSLRQLVEADAN-------------------SLKQILNALTLGK--ADLEAQVESLKEE
-LLCLKNSHREEIDSLQS--QLGDRL--HIEVTAAS------------------------
---------------------------------------------------SVDLNQVLQ
ETRCQYESI----METNR----KDVEQWFNTQM--------------------EELNQQ-
-VVT---SSEQQQCCQ-KEIVELRR-TVNALEVE--LQA------------QHRM--RD-
-----SQECFLTEIEAHYTALLTQIQCLIDNLEA--------------------------
QLAEIRCALERQNQEYESLLDIK---SRLECEIATYRSLLEGLD---C------K---LP
CNACATK----------CELST-CTPCKARAT------------------------ECTA
P--VCTA---------SAP--RGARKPCSAYDP--LSRILVKILT----------IT--K
EIKDGKVISSHEHVQ--------PCYITRPAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PT-----
----MSC-RTS--------------CSSRPCIPNSCH---S-CTLPG-AC-NIPANIGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-ME-KVRQLERENA--ELESRIQ-ERNQQQ
DPL--VCPAYQAYFRTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLGEIRADLERQNQEYQVLLDIR---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACGKPIGPCVSNPC------------------------T---
------PCPPPAPCTPCVPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSSG-SLKSPGKA
-------------------GGGSTRTSTMF-SSSSC-KLPSLSRGARSFSVC--------
--------SAG--------------LGRNNYRISSCL---PALCHPM-GGFATSYGT-GG
GWFG---EGILTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQVLND---
-------------------------RLASY-LE-KVRQLEQENA--SLESRIR-EWCEQQ
VPY--MCPDYQSYFRTMEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
EVSLRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----RDAEDWYDTQT--------------------EELNQQ-
-VVS---SSEQLQSCQ-AEIMELRR-TVNSLEIE--LQA------------QQSM--RD-
-----ALDSTLAETEARYGSQLAQMQCMIGNVES--------------------------
QLGEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---S---------KLP
CNPCAPD----------YSPSKSCLPCLPAV-----------------------------
------SCSTGAARANCSPH-----PVCVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PA-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-ME-KVRQLERENA--ELECRIQ-ERNQQQ
DPL--VCPAYQAYFRTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-ET
ELGLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKRNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAM----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHCM--RN-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLGEIRADLERQNQEYQVLLDVK---ARLECEINTYRGLLESED---CK---------LP
CNPCATS----------NACGKPIGPCVSNPC------------------------A---
------PCPPPAPCTPCVPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSCESCL----PA-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-MEKKVRQLERENA--ELECRIQ-ERSQQQ
DPL--VCPAYQAYFRTIEELQQK--ILCAKSENARLVVQIDNAKLASDDFRT---KY-QT
ELSMRQLVEADIN-------------------SLRRILDELTLCK--SDLEAQVESLREE
-LLCLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWYTTQS--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHCM--RN-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLGEIRADLERQNQEYQVLLDIR---SRLECEINTYRSLLESED---CN---------LP
CNPCATT----------NASGGCCGPCGS---------------------------S---
---KR-CC----------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------FSRIDLRSVI-IS
--------------IRLIDQ-----------------MYKHVVVKGGHVQV---GGSGGG
NYRKIS------------VGG----YASSVYAGAGGRNTKVSTDGS--PGELTSRHLY--
--IK---TVSIGG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMRNLNN---
-------------------------RLATY-LE-KVRSLEKANA--ELEGQIK-EWYQQN
SGF--GKRDDAHYFQVIEELTKQ--IVNAKMENGKLLLQMDNATLALDDFKM---KL-EY
ELNLGAAVEKDLS-------------------ELRKVVDDLTMTR--TDLESQIESLKEE
-MVYLKKNHTQDMVGLHK--QEG-TI--DVEVDAAP------------------------
---------------------------------------------------SVDLGKTME
DMRSQYEQL----VEKQR----LEAKYGFDRKV--------------------EEWNEE-
-VQT---NTAELEKCR-KDLSELKH-KVQDLEIE--SQA------------ELSK--RK-
-----AAGNALDNVNSRYTMELADKQEKIARFEE--------------------------
HLQQTRRDVGFQIQEFTILFDLK---NRLEAEISTYRRLLDAEG---Q------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MATQICTPTFSMGSV-KGLCGT
-------------------AGGISRVSSIR-SVGSC-RVPSLAGAS----------GCIS
SVRS------------------------GLSSLGGCL---PGSYLSA-GC-HPSGFVGSG
GWFF---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIR-EWYESQ
IPY--TCPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVSALRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRILE
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRRLLEGED---C---------KLP
PPPCAMA----------CKPAIRIPSVPP-------------------------------
--------APCAPA-----------VACSPAPQ-----VGTQIRT----------IT--E
EIRDGRVISSREHLQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------SS-SCS----LGC----------
------------------------------------------------TKPLGARNV---
--C--ISP----VDVECQPR-------VECLLANVAHANRIRVGS---TPLGRPSLCLPP
SCHA-AC------------------------------------PLPG-TC-HVPGNIGIC
GAYG---EGSLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMRFLND---
-------------------------RLANY-LE-KVRQLERDNA--ELETKLR-EWSRCH
ESS--VCPDYQSYFRTIEELQQ--KILCSKAENARLIVQIDNAKLAADDFRI---KH-ES
ELALRQLVEADMC-------------------GTQKLLDDATLAK--SDLEAQQESLKEE
-QLALKSNHEQEVKILRS--QLGDKL--RIELDTEP------------------------
---------------------------------------------------PVDLSRVLG
EMRCQYETM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRC-SVNALEVE--RQA------------QHTL--KD-
-----CLQNSLCEAEARYGTELAQMQSLISNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLEDEINTYRKLLESED---C------K---LP
CNPCSTP----------ASCTL----CP-----------------------------GR-
---APAA-----------------CGPPSASGA---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCSL----PT-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEQRIL-ERSQQQ
DPL--VCPAYQAYFRTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLYLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLGEIRADLERQNQEYQVLLDIR---SRLECEINTYRGLLESED---RK---------LP
CNPCATT----------NTCDKPIGPCVPNP-----------------------------
----------------CVTR-P-RYGP----------------C----------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MATQICTP-TFSAG----L----------
-------CG------------------------------SAG----SISRVSSFRSX---
--------------XXXXXX------XXAGA---AS-SVRSGLS---GLWSCLPGSYLPA
-----GC---------------------------------------H-P----SSFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELECRIR-EWYESQ
IPY--ICPDYQSYFKTIEDLQQK--VLLTRAENTRLVLQIDNAKLAADDFRT---KY-ET
ELSMRQLVEADIN-------------------GLRRMLDELTLCK--ADLEMQVESLKEE
-LLCLKRNHEEEANALRC--QXX--X--XX-XXXXX------------------------
---------------------------------------------------XXXXXXXXX
XXXXXXXXXX-XXXXXXX----XXXXXXXXXXT--------------------EKLNQ--
-QVL---TRKQGQECQ-AEIIEVIC-TVNDLEI---LQA------------QHSM--RN-
-----SLESTLAETEARYSAQLAQMQCLITNVES--------------------------
QLAEIRCDLERQNHEYQVLLDVK---ARLESEIATYRRLLDGED---C------RLPA--
-HPCATE----------CKPALR------------------------------------V
P---YLPSMPCATSVPCAP-A---------------PQLSAQIRT----------IT--E
ELRDGKVISSREHVQ--------SRPL-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MTSDH---
--C--SSP----L---RGQVSE-AKAACQGLLASLAHANRVRVGT---TPLGRPNLCLPN
SCHN-AC------------------------------------PLPG-TR-NIPANIGSC
GAYG---EGTLNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

HEKE---------------------------------TMQFLND---
-------------------------RLANY-LQ-KVRQLEQENA--ELETKIR-EWSKCH
ETT--MCPNYQCYFQTIEELQQ--KILCIKSENNRLVIQVDNAKLAADDFRT---KY-QM
EHSLYQLVEADIC-------------------GLRRALDDLTLAK--CDLEAQVESLKEE
-LLCLKKNHEQEVHTLTC--QLGDRL--LIELDTEP------------------------
---------------------------------------------------TVDLSRVLE
EMRCQYETM----VETNR----RDVEQWFQAQS--------------------EGISLQ-
-ATS---CSEELQCCQ-SEILELRR-TVNALEVE--LQA------------QHHL--KD-
-----CLQNSLCEAEARFGTELAQMQCLISTVEE--------------------------
QLAEIRADLERQNQEYQVLLDVK---ARLEGEIATYRNLLESED---F------K---LP
CNPCTTP----------ASS------TP-----------------------------CP-
---APAACTPCPPCPSRPL--QASYGPCSSPQR---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MPSSCCI-TNTSSASLKSSA--
------------------------RPSSVCSSNMGS-RSELCLGYVCQPLQCMPSICMPT
TYRPASCLSKT--------------YLSSSCQPSNRR---PTG--------CISSSMGTY
GLFC---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQVLND---
-------------------------RLANY-LE-KVRQLEKENA--ELEGKIQ-DVYQAQ
VLT--MCPDYQSYFQTIEELQQK--VLCTKAENARMIVHIDNAKLAADDFRT---KY-ET
ELALRQLVEADTN-------------------GLRRILDELTLNK--ADLEAQVESLKEE
-LLCLKRNHEEEVGVLRQ--QLGDRL--NIEVDAAP------------------------
---------------------------------------------------PVDLTRMLE
EMRCQYETM----VQTNH----RDVEEWFNMQM--------------------EELNKQ-
-VAT---SSEQLQSYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLGETEGRFTSQLSQMQCMITNVES--------------------------
QLADIRCDLERQNQEYKVLLDVK---ARLECEIDTYRGLLESED---S---------NLP
SP-CSNF----------LSN----------------------------------------
------------------------ISSCFFCYS-----ESYPTKA--------SVVN--S
HACQGQAVTI--HM--------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRQ-----------------SFHRSLSSSSQGPA---LSMSGS
LYRKGT----------VQRLG----AAPSVYGGAGGHGTRISV-SK--AVMSYGGDLS--
--NG---SDLFGG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NGKL---------------------------------AMQNLND---
-------------------------RLANY-LE-KVRSLEQSNS--RLEAQIK-QWYETN
APS--TIRDYSSYYAQIKELQNQ--VKDAQVQNAQCVLRIDNAKLAAEDFRL---KF-ET
ERGMRIAVEADLQ-------------------GLSKVYDNLTLQK--TDLEIQIEELNKD
-LALLKKEHQEEVEVLRR--QLGNNV--NVEVDAAP------------------------
---------------------------------------------------GLNLGEIMN
EMRQRYEVL----AQKNL----QEAKEQFERQS--------------------QTLQQQ-
-VTV---NTEELKGFE-VQVTELRR-TYQNLEIE--LQS------------HLSM--KE-
-----SLERNLEDVKARYASQLAAIQEMLSSLEA--------------------------
QLMQIRSDTERQNQEHNILLDIK---TRLEQEIATYRRLLEGED---IK---------T-
------TE---------YQLST--------------------------------------
-----------------------------LEMK--DIKKTRKIKT----------VV--E
EVVDGKVVSSEVKEI-EESV--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----PN-----
----VSC-RST--------------CSSRPCVPPSCH---T-CTLPG-AC-NIPANVGNC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELESRIR-EWCQQQ
VPF--VCPSYQSYFRTIEELQQK--ILCSKAENARLVVQIDNAKLASDDFRT---KY-ET
EVGLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----RDVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTETEARYSSQLSQLQCMITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLECEINTYRGLLESED---CK---------LP
CNPCATT----------NACDKPIGPCVSNPC------------------------T---
------------------QR-A-RCGP----------------CN--------TFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------ST---------MPYNCCL----PN-----
----LSC-RTS--------------CASRPCLPPSCH----SCTLPG-AC-NIPANVGTC
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELEGRIQ-EWCQEQ
VPY--VCPDYQSYFRTIEELQQK--ILCTKAENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------SLRKILDELTLCK--SDLEAQVESLKEE
-LICLKRNHEEXXXXX-XXX-XXXXX--XXXXXXXP------------------------
---------------------------------------------------TVDLNRILN
ETRCQYEAV----VENNR----RDVEEWFITQT--------------------EELNKQ-
-VVS---SSEQLQNCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTETEARYSSQLSQVQCMITNVED--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEISTYRGLLESED---CK---------LP
CNPCATT----------NACGKPIGPCPVTN-----------------------------
---PCIPCAPCAPCTPCVPR-S-RCGP----------------CT--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTKGSTV-TISSS---------------
------------------------------------------TPPQNCSGNTNFRTNSSS
-N------------KSCCHD---------------G-QSTGCALQTPQGQGCGSSPCL--
------YRCPH--------------YLIRT-----YS----F-----------HPCLDDG
SRCT---EGI-NTH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1063)

EKE---------------------------------TMQILNE---
-------------------------RLANY-LE-KVRMLEGENA--DLEDKIQ-EACSKA
LPI--LCPDYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---NY-EA
ELSLRQLVEADAN-------------------GLKQILDALTLSK--ADLEARVQSLTEE
-LLCLKTNHEEEVNSLQC--QLGDRI--NIEVTAAP------------------------
---------------------------------------------------SVDLNQILQ
EMRCRYESI----METNR----KDVEEWFNTQM--------------------EELNQQ-
-VVS---SSQQQQCCQ-KDIIELRR-TISALEIE--LQA------------QHRM--RE-
-----SQECILTETEARYTALLAQIQSLIHNLEA--------------------------
QVADIRSALQRQSQEYEVLLDIK---SRLECEIATYRSLLESLD---G------R---LP
CNPCATK----------WEPS-----CQARAM------------------------ECFT
P--VYTS---------SSL--PGIHKPCRASGP--PSRILVKICT----------IT--K
EIKDGKVISSYEHVQ--------PCYITRATKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MTSNIIRT-SSSY---PLG----------
------------------------------------------------SKVPGVTNI---
-----VSS----IDVGGRPGAD-VKAASMCFSAAMAHNNRVRVGT---TSLGRPSLCLPN
SCQS-AC------------------------------------PLPG-TL-NIPANIGNC
GNYG---EGFLNGH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLEQENA--ELETKIQ-EWSKCH
ASY--VCPDYQSYFRTIEELQQ--KILCTKAENTRLVIQVDNAKLAADDFRI---KY-ES
ELSLRKLVEADMC-------------------GMNKLMDGLTLAK--CDLEAQVESLKEE
-QFSLKSNHEQEVHNLQC--QLGDKL--HIELDSAP------------------------
---------------------------------------------------PVDLNRVLG
EMRCQYEAM----VETNR----NDVEQWFLAQS--------------------EGISLQ-
-EMS---CSEELQCCQ-SELLELRC-AVNALEIE--RQA------------QHKM--KD-
-----CLENSLCESETRYSTELAQMQYLISNVEE--------------------------
QLAEIRADLERQNHEYQVLLDVK---ARLECEISTYRNLLESED---C------K---LP
CNPCATP----------ANCAP----PP-----------------------------CA-
---PRPSCAPRTTCIPSR----SACGTNLSNRF---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MSCESCL----PA-----
----LSC-RTS--------------CSSRPCIPNSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENG--ELGTRIQ-ERNQQQ
APL--VCPAYQSYFATIEQLQQK--ILCAKSENARLAVQIDNAKLASDDFRT---KY-QT
EQSLRQLVESDIN-------------------SLRRILDELTLCK--SDLEAQVESLREE
-LLCLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCLITNVES--------------------------
QLGEIRADLERQNQEYQVLLDIR---SRLECEINTYRSLLENED---CN---------LP
CNPCATT----------NASGSSCGPCGG---------------------------C---
---QKRCC----------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---KPAHI----------HLQQLTCFSITCPST---------MSYSCCL----PS-----
----LGC-RTS--------------CSSRPCVPPSCH----GHTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFTIIEELQQK--ILCAKAENARLVVNIDNAKLASDDFRS---KY-QT
EQSLRRLVESDIN-------------------SIRRILDELTLCK--SDLESQVESLREE
-LICLKKNHEEEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CNPCATT----------NASGNSCGSCGTS------------------------------
Q--KCC-CN---------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------M------SANNSC-QSTGHEPRTPQSRVCQSTHRL--
------CRTPI--------------YLISN-----FC----V-----------HPSLDDC
SWLG---EGI-NS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1075)

NEKE---------------------------------TMQILND---
-------------------------RLANF-LE-KVRMLERENA--ELECRIQ-EERNKE
LPV--LCPNYLSYYTTIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---NY-EA
EVSLRQLVEADAN-------------------SLRKILDALTLSK--ADLEARVQSLKEE
-LLCLKNSHQEDINSLWG--QLGDRL--NIEVTAAP------------------------
---------------------------------------------------SVDINQILQ
EMRCQYESI----METNR----KDVEQWFNTQM--------------------LELNQQ-
-VVT---SSQQQQCSQ-KEIAELRR-TVNALEVE--LQA------------QHRM--RD-
-----SQECILTETEARYTTLLAQIQSLVHNLEA--------------------------
QLAEIRSALERQNQECDILLDIK---SRLECEIATYRSLLESSD---C------K---LP
CNPCATR----------CKPST-CTPSKPSTV------------------------ECTA
P--VFTS---------SAP--NGILKRYNVCGP--PSRILVKICT----------IT--K
EIQDGKVISSHEHVQ--------PCFIPRLAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MDFSRR-----------------SVHRSLSSSSQGPA---V-----
--RKGG----------QQRLG----AAPSVYGGAGGYGTRIST-AS--SALSYGNSLG--
--GG---SDLFPG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1177)

SEKM---------------------------------AMQNLND---
-------------------------RLASY-LD-KVRSLEQSNT--KLEALIK-QWYEAN
APS--GIRDFSAYYQQIEELQNQ--IKNAQLENSRCTLQIDNAKLAAEDFRL---KF-ET
ERGLRLAVEADLQ-------------------GLRKILGELTLQR--SDLEIQIEELNKE
-LDLLKREHEEEVDVLRR--QLGNTV--NVEVDAAP------------------------
---------------------------------------------------GLNLGEIMS
EMRQKYEVL----AQKNL----QEAKEQFERQT--------------------ETLQQQ-
-VTV---DTQELKGIE-AQVTELKR-TQQILEID--LQS------------QLSM--KE-
-----SLERTLEETEARYGNQLATLQGMLGSLEA--------------------------
QLVQVRSDTERQNNEYNALLDIK---TRLEQEIATYRRLLEGDD---A------------
------------------------------------------------------------
------------------------------------VKKTRKIKT----------VV--E
EVVDGKVVSSEIKEI-EEPV--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNCCL----SN-----
----VSC-RSS--------------CSSRPCVPHSCH---G-CTLPG-AC-NIPANVGNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEARIQ-ERNQQQ
DPL--VCPSYQSYFRTIEELQQK--ILCSKSENSRMVVDIDNAKLASDDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDELTLCR--ADLEAQVESLKEE
-LLCLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNQVLN
ETRSQYEAL----VETNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCMITNVES--------------------------
QLAEIRADLERQNQEYQVLLDIR---ARLECEINTYRSLLDSED---CK---------LP
CNPCATT----------NACDKPIGPCVSNP-----------------------------
----------------CVTR-S-RCGP----------------CS--------NFGR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------M------------------------------TSSGSPVRGSSESCARDI---
----------------------------------GC-DTA--------STRPPEATCLPS
AGPVSGCQARS--------------FLPRTYLSPGCL---APCYLAA-GC-DSPCLVENG
AWCE---DGAFNSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1069)

EKQ---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRYLEETNE--QLESKIQ-GQCEPD
ALF--VCPDYQCYFDSIEELQQK--ILCTKAENSRLAVQLDNCKLAADDFRS---KY-ES
ELSLRQLVENDIS-------------------GLRGILGELNLCR--SNLEAHAESLKDD
-LLCLKKSHQEEVSVLHE--QLGDRL--NVELDTAP------------------------
---------------------------------------------------TVDLNGALE
EMRCQYETV----LADNR----RDAEEWFAAQA--------------------EELSQQ-
-QLS---SAEELTGCQ-TEILELKR-TANALEIE--LQA------------QQHL--TD-
-----SLECTVVETEAQYSSQLAQMQRLIDNVET--------------------------
QLAEIRCDLERQNQEYEVLLDTK---ARLECEINTYRGLLDSED---SR---------LT
SNPCPV-----------V-------STSSNA-----------------------------
-------CESSSAYVLCTV--ENCCA----------------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVAPSCH---S-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENA--ELEHLIR-ERSQQQ
EPL--LCASYQSYFKTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKSNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNQVLN
QTRSQYEAL----VDTNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLAQVQCLISNVES--------------------------
QLAEIRGDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CN---------LP
SNPCATT----------NACSKPIGPCVSNSC------------------------T---
------PCIPPAPCTPCAPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MYSLPVTP
--------------KDVSRR-----------------SFHRSLSSSLQGS----------
---AVS----------MQRLG----MAPSVYGGAGGRGTRISTTSR--NMVSSGSDLI--
--GS---GDLFVG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

NEKT---------------------------------TMQNLND---
-------------------------RLASY-LD-KVRALEQSNS--ELEVQIK-QWYETN
APS--GGRDYSAYYRQIEELRNQ--IKDAQLKNARCILQIDNAKLAAEDFRL---KF-ET
ERGIRLTVEADLQ-------------------GLSKVFDDLTLQK--TDLEVQIEDLNRD
-LALLKKEHQEEVDGLHR--HLGNTV--NVEVDAAP------------------------
---------------------------------------------------GQNLGAIMN
EMRQKYEDM----AQKSL----QEAKEQFERQT--------------------AALQQQ-
-VTV---NTEELKETE-VQLTELRR-TFQSLEIE--LQS------------YLSM--KE-
-----SLEHTLEETKARYGIQLANLQSLLSSLEA--------------------------
QLMQIRSDTEHQNNEYHILLDIK---TRLEQEIATYRRLLEGED---VK---------T-
------ME---------YQLST--------------------------------------
-----------------------------QEEK--DIKKTRKIKT----------VV--E
EVVDGKVVSSEVREV-EENI--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MT---
--S--DHC----SSLLSEQVSE-TSAASLCLLANVAHANRVRVGS---TPLGRPSLCLPP
TCHT-AC------------------------------------PLPG-TC-HIPGNIGIC
GAYS---ENTLNSH

PF00038 // ENSGT00900000140814_1_Domain_1 (495, 1075)

EKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERDNA--ELETKLR-ERSKCH
EST--VCPDYQSYFCTIQELQQ--KILCTKSENNRLVVQIDNAKLAADDFRT---KY-ET
ERSLHQLVEADIC-------------------GLRRVLDNLTLAK--CDLEAQLESLKEE
-LLCLKKNHEQEARTLRG--QLGDKL--RIELDIEP------------------------
---------------------------------------------------TIDLSRVLG
EMRGQYEAM----VETNR----QDVEQWFQAQS--------------------EGISLQ-
-AMS---CSEELQCCQ-SEILELRR-SVNALEVE--LQA------------QHTL--KD-
-----CLQNSLCEAEDRYGTELAQMQSLINNVEE--------------------------
QLSEIRADLERQNQEYQVLLDVK---ARLENEIATYRNLLESED---C------K---FP
CNPCATP----------AFS------TP-----------------------------SP-
---APAACAPC---SR------ATHGLCSSTGY---------------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MTSSCCV-TNNLQASLKSCP--
------------------------RPASVCSSGVNC-RPELCLGYVCKPMACLPSVCMPT
TFRPASCLSKT--------------YLSSSH-----Q---AAS--------GISGSMGPG
SWYS---EGAFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMRFLND---
-------------------------RLASY-LT-MVRQLEQENA--ELESRIQ-EASHSQ
VLT--MTPDYQSHFRTIEELQQK--ILCTKAENARMVVNIDNAKLAADDFRA---KY-EA
ELAMRQLVEADIN-------------------GLRRILDDLTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVGSLRC--QLGDRL--KIEVDAAP------------------------
---------------------------------------------------PVDLTRVLE
EMRCQYEAM----VEANR----RDVEEWFNMQM--------------------EELNQQ-
-VAT---SSEQLQNYQ-SDIIDLRR-TVNTLEIE--LQA------------QHSL--RD-
-----SLENTLTESEARYSSQLAQMQCMITNIEA--------------------------
QLAEIRADLERQNQEYQVLLDVR---ARLEGEINTYRSLLESED---C---------KLP
CNPCSTP----------SCTPCVPS-----------------------------------
---------PRVPRTVCVTR--TVGVPCSPCPQ-----GRY-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASKCLKASFSTG-SLKSPGGA
-------------------AGGSTRVATVY-SSSSC-KLP---HGLHSFSVC--------
--------PAG--------------LGRSSFGAAGCL---PVPCLPV-GGFATSYGMAG-
GWFG---EGVLTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQSLND---
-------------------------RLASY-LE-KVRQLERENS--ELERRIR-EWCEQQ
VPY--MCPDYQSYFRTIEELQKK--TLCSKAENARLVVQIDNAKLAADDFRT---KY-ET
ELSLRQLVESDIN-------------------GLRRILDDLTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNRVLD
EMRCQYETL----VENNR----REAEDWFDSQT--------------------EELNQQ-
-VVS---SSEQLQNCQ-VDIIELRR-TVNALEIK--LQA------------QHSM--RD-
-----ALESTLVETEARYGSQLSQMQGLIGNVEA--------------------------
KLAEIRADLERQNQEYQVLLDVR---ARLECEISTYRGLLESED---C---------KLP
CNPCGPD----------HVPSKSCLPCLPPA-----------------------------
------SCSPGTVRTTCSPR-----PVCVPCPG-----GRF-------------------
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDTAGYTT-ASS-----------------
-----------------------------------------STLLPNCSRITNVRTTASH
--------------HSCPGR----------------------------------------
-------VLRKPQ--------------PQGCQPSAGF-CGTPICRT--DTFSACLPLDGR
GWCG---DG-LNS

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMRILNH---
-------------------------RLAKY-LE-KVQMLERENM--ELEWKIQ-QECSKE
VPV--VCPEYLSYYTAIEELQQK--ILCTKAENSRLVSQIDNTKLAADDLRA---XX-XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXX----------
----------XEIHSLQS--QLGDRF--NIEVTAAP------------------------
---------------------------------------------------SVDLNQVLQ
DMRCQYESI----VETNH----RDVEQWFNMQM--------------------EELNQQ-
-VVT---SSQQQQCCQ-RELIELRR-ALNTLEIE--LQA------------QHRM--RD-
-----SQEGILAETEARYTALLGQIQGLINSLEA--------------------------
QLTESRCALERQNQEYEILLDIK---SRLECEIATYRSLLESLD---GK---------LP
CNLCAT-K---------RDPSTGTSW--KA------------------------------
---RAMEGM-VPVCASLAR--HGFHEPCSVCRS--LPRILVKICT----------TT--K
EIKDGKVISSHEHVQ--------PCYITRAAKV-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MASQLCSPIFSSGSL-RGHCGA
-------------------TSGISRVSCVR-SVGSC-RGPSLAGVS----------GSAS
SIRL------------------------GLSSLGSCL---PGSFLSS-GL-HSSGFAGAG
GWLC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENT--ELESRIR-EWYESQ
VPY--ICPDYQSYFKTIEELQQK--ILLTKADNARLVLQIDNAKLAADDFRT---KY-ET
ELGVRQLVEADTN-------------------GLRRILDELTLCK--ADLEMQVESLKEE
-LICLKKNHEEEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILD
EMRCQYETL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCYQ-TEIIELRR-NVNALEIE--LQA------------QHSM--RN-
-----SLECTLAETEARYSSQLAQMQGLIGNVET--------------------------
QLAEIRCDLERQNQEYQVLLDVK---ARLESEIATYRRLLEGED---C---------KLP
AHPCATE----------CKPAVRVSYVSS-------------------------------
--------GS-----------------CAPAPQ-----LSTQIRT----------IT--E
EIRDGKIISSREHVQ--------PL---------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-CTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1068)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELESLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCTKSENARLVVQIDNAKLAADDFRT---KY-QT
ELSLRQLVESDIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKSNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRSQYEAL----VETNR----REVEQWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CN---------LP
SNPCATT----------NACSKSIGPCVSNPC------------------------T---
------PCIPPAPCTPCAPR-P-RCGP----------------CN--------SFVR---
----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------LTSTIIR-SSC-----------------
-----------------------------------------PLGIPKASAGTNVCITSIG
--------------VGGRPG-----------------AEI---KA--------ASQCLSA
SLAHAN----------RVRVGSTPPGMPSLCLPPSCK---AACSLS--GTCHIPTNLGSC
GLSR---EGALNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 672)

QEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVLRLERENA--ELEAKIG-E-----
------VPDCQSYFRTIERLQWK--ILCSKVENARLAIHISNAKLAADDFRI---RH-ER
EFSLRQLVQADVC------------------TGLHTLLEDVTLAT--SNLEAPQESLREK
-QGYFMSSHKQ-------------------------------------------------
------------------------------------------------------------
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------------------------------------------MSYSCCL----PS-----
----LGC-RTS--------------CSSRPCVPPSCH---G-HTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFTIIEELQQK--ILCAKAENARLVVNIDNAKLASDDFRS---KY-QT
EQSLRRLVESDIN-------------------SIRRILDELTLCK--SDLESQVESLREE
-LICLKKNHEEEVNTLRS--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNH----REVEQWFATQT--------------------EELNKQ-
-VVS---SAEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQSLITNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
CNPCATT----------NASGNSCGPCGT---------------------------S---
---QKCCCN---------------------------------------------------
----------------------------------------------------------

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--------------------------------------MASKCLKANFSSG-SLKSPGGT
-------------------GGGSTRVSAMY-SSGSC-KLPSLSRGSRSFSVS--------
--------SAG--------------LGRGSYRAASC--------LPA-GGFATSYGM-GG
GWFG---EGIFTG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1064)

SEKE---------------------------------TMQVLND---
-------------------------RLASY-LE-KVRQLERENA--ELEQRIR-EWCEQQ
VPY--MCPDFQSYFRTMEELHKK--TLCSKSENARLVVEIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--SDLEAQVESLKEE
-LLCLKKNHEEEVNSLRC--QLGDRL--SVEVDAAP------------------------
---------------------------------------------------PVDLNRVLE
EMRCQYETL----VENNR----RDAEDWYDAQT--------------------EELNQQ-
-VVS---SSEQLQNYQ-ANIIELRR-TVNGLEIE--LQA------------QQSM--RD-
-----ALDSTLAETEARYSSQLSQMQCLITNVES--------------------------
QLSEIRADLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---G---------KLP
CNPCAPD----------QSSSKPRLLCLPAA-----------------------------
------SCSPGPTPLTCSPR-----PVCVPCPG-----GRF-------------------
----------------------------------------------------------

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--------M------------------------------ASDGSPGCCSSEPCAEAP---
----------------------------------DC-AAA--------SPCPTDTTCLPS
TCATSRCQTPS--------------FLCRAHLSAGRL---SPCYFAG-GC-NSPCLVGSC
AWCE---EGAFNSNEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-RVRSLEENNA--ELECRIR-EQCEPD
APL--VCPDYQRYFDTIEELQ

PF00038 // ENSGT00900000140814_1_Domain_1 (622, 1068)

QK-------------------------------------
------------------------------------------------------------
-----------EVNLLRE--QLGDRL--SVELDTAP------------------------
---------------------------------------------------TVDLNKVLD
EMRCQYERV----LANNR----RDAEEWFAAQT--------------------EELNHQ-
-QMS---SAEQLQGCQ-SEVLELKR-TANTLEIE--LQA------------QQTL--TE-
-----SLECTVAETEAQYSTQLAQMQCLIDSVEH--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEINTYRGLLESED---C------------
------------------------------------------------------------
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--------------------------------------MATQTCTPTFSTGSI-KGLCGT
-------------------AGGISRVSSIR-SVGSC-RVPSLAGAA----------GYIS
SARS------------------------GLSGLGSCL---PGSYLSS-EC-HTSGFVGSG
GWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1078)

SEKE---------------------------------TMQFLND---
-------------------------RLANY-LE-KVRQLERENA--ELESRIQ-EWYEFQ
IPY--ICPDYQSYFKTIEDFQQK--ILLTKSENARLVLQIDNAKLAADDFRT---KY-ET
ELSLRQLVEADIN-------------------GLRRILDELTLCK--ADLEAQVESLKEE
-LMCLKKNHEEEVSVLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------PVDLNKILE
DMRCQYEAL----VENNR----RDVEAWFNTQT--------------------EELNQQ-
-VVS---SSEQLQCCQ-TEIIELRR-TVNALEIE--LQA------------QHSM--RN-
-----SLESTLAETEARYSSQLAQMQCLISNVEA--------------------------
QLSEIRCDLERQNQEYQVLLDVK---ARLEGEIATYRHLLEGED---C---------KLP
PQPCATA----------CKPVIRVPSVPP-------------------------------
--------VPCVPS-----------VPCTPAPQ-----VGTQIRT----------IT--E
EIRDGKVISSREHVQ--------SRPL-------------------------------

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------------------------------------------MTYSCCL----PS-----
----LSC-YTS--------------CASRPCVPPSCH---G-CTLPG-AC-NIPANVSSC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELESLIR-ERCQPQ
EPL--VCANYQSYFRTIEELQQK--ILCSKSENARLVVQIDNAKLASDDFRT---KY-ET
EMSLRQLVESDIN-------------------GLRRILDELTLCR--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TMDLNRVLD
ETRCQYEAL----VDTNR----REVEEWFTTQT--------------------EELNKQ-
-VVS---SSEQLQSCQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLTESEARYSSQLSQVQCMITNVEE--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEISTYRGLLESED---CK---------LP
CNPCSTT----------NACDRPFGPCISNPC------------------------T---
------------------TR-A-RCGP----------------CN--------TFMC---
----------------------------------------------------------

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------------------------------------------MPYNCCL----PN-----
----LGC-------------------YTRPCMAPSCH----TCPLPG-AC-NIPANVSNC
GWLC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

NEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERENG--ELESRIQ-E-CQQQ
VPF--ACSDQS-YFD---IEQQR--ILTGKAENSRLVVQIDNAKLATDDFRT---KY-ES
ELSLRQLVEADIN-------------------SLRRILDELTLCK--ADLEAQVESLKEE
-LLCLKQTHEQEVNTLRS--QIGDRL--NVEVDAAP------------------------
---------------------------------------------------TVDLNRVLN
ETRCQYEAL----VETNR----RDVEEWFATQS--------------------QELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RN-
-----SLENTLNESEARYSSQLAQLQGLISNVES--------------------------
QLAEIRCDLERQNQEYQVLLDVR---ARLECEISTYRSLLESED---CK---------LP
CNPCATT----------NAC----GPCTSYPC------------------------A---
------------------PR-A-QCGP----------------CN--------TFVC---
----------------------------------------------------------

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--------------------------------T---------MPYNFCL----PS-----
----LSC-RTS--------------CSSRPCVPPSCH---G-YTLPG-AC-NIPANVSNC
NWFC---EGSFNG

PF00038 // ENSGT00900000140814_1_Domain_1 (494, 1069)

SEKE---------------------------------TMQFLND---
-------------------------RLASY-LE-KVRQLERDNA--ELENLIR-ERSQQQ
EPL--LCPSYQSYFKTIEELQQK--ILCSKSENARLVVQIDNAKLAADDFRT---KY-QT
EQSLRQLVESDIN-------------------SLRRILDELTLCR--SDLEAQVESLKEE
-LLSLKQNHEQEVNTLRC--QLGDRL--NVEVDAAP------------------------
---------------------------------------------------AVDLNQVLN
ETRSQYEAL----VETNR----REVEQWFATQT--------------------EELNKQ-
-VVS---SSEQLQSYQ-AEIIELRR-TVNALEIE--LQA------------QHNL--RD-
-----SLENTLTESEARYSAQLSQVQRLITNVES--------------------------
QLAEIRSDLERQNQEYQVLLDVR---ARLECEINTYRSLLESED---CK---------LP
SNPCATT----------NACEKPIGSCVTNPC----------------------------
-----------------GPR-S-RCGP----------------CN--------TFGY---
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