Query Results 

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNNQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRINQKAE
RGAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAK

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGQSGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVSA------------RGDPGIQGIKGEKGESCLSC
SSVVGAQHLASST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGKAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGTSVSGPPGRDGQQGQTG---PRG-----TPGEKGPRGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVLGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNNEGDPGCIGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPP

PF01391 // ENSGT00900000140804_4_Domain_13 (1432, 1519)

GSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGLYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWVPGLWLLGLWATFSHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVSSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
SPAGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQHSQVDAQLTGRISQKAE
RGAKVHRETAA-----DECPPCVHG---ARNSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGAQG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGFPGSTGEKGQKGEK-
GDGGIKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGLPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGMPGKEGPGGKPGKPG---VKGEKGEPCEVCP
TLPEGFQNFIGLPGKLGPKGEPGDPSPA------------RGDPGIQGIKGEKGEPCLPC
VSVVGAQHLASSTGA

PF01391 // ENSGT00900000140804_4_Domain_5 (736, 800)

GGEVGSPGFGLPGLPGTAGVP---GLKGEKG--NFGEAGPAGS-P
GPPGPMGPEGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNIEDGEVRVVALPGASGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGMPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDMAGRPGQP-GPKGEQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1039)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGSTGEKGAQGS-----P
GVKGATGPMGPPG-----PPGHDGQQGQTG---ARG-----MPGEKGSRGEKGELGECSC
PSRGDVVFS---GMPGAPGM----W---MGNSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNN

PF01391 // ENSGT00900000140804_4_Domain_12 (1306, 1363)

EGDPGCVGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGPKGDP
GAAGQKGQPGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGQCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWTPGLWLLSLWVTFSHGANTGEQCPPSQQEGLKLEHSINLSANL-SFNLIRRLSLMKTT
AIKKIRNPKGGPLILRLGATLLTQPTRRVFPQGLPEEFAL-------KHTYQNTWYLFQV
TDGNGYPQISLEVNSQEQSLELRAQDQDGEFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSQPLGPRRPVQPVGHVFLGLDAEQGKPVSFDLQQAYIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAKLMGRTSQKAE
KGT--------------KCPPCVHG---TQESNVSE---------------------GGT
GERGLPG-PAGPKGEKGARG----------------------------------------
-------------NDCVLISPDAPLQVRPR-------GEALDPSGCPGPPSILCPKGEKG
VSGASVSMEPGLGESG------------PGSLFLPHPLFCGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGEPGGPPGPKGDKGSSGIPGKEGPGGKPVSDP---SSGERGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPV------------RGDPGIQGIKGEKVRELWSP
VAPLCLS-----G--------------------------GLSDPFS--SLS--RGSPAHL
GPPGQVGPAGSKGEKGEPCEPCSALSKPQDGDSHVVHLLGPAGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 881)

GLPGKQG
KAGER-GLKGQKGEPGSPGDPGRPGTTGRPGLSGEPGVPGPLGPKGEKG-DACTACPSLQ
GAVTDMTGLPGKP-GPQGERGPEGVGRPG----KPVSSSGLPSA----GVI---------
--LLPLQGEPGP-PGVGAQGPQGEPGAQGLPGIQGLPGPRGPPGPTGEKGAQVSFCFLGC
---------------------------------------------WVFR-----------
------------GFEYPGSRHREHGPEPGPLSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGLPGIDGLPGQPGLTAEVVG----
--------------TSQHSLSSICGDCVQGQRTVALSSLEKGEKGDQAIPGVPGLDNCAR
VGTVLAHP----------------------------GVVVGGDNMEKDSDCA

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1361)

GSPGLPG-
-SPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPQG-----LCGF--CLSP-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGPAGEKGEP-GPPGSEGLPGSP
GPVVSER----------GQGDGF--------QGQP-GFPGPPSHVGSLGGDGWGRGQKSE
GIRGPTGLPGPTGSPGPPGIQVSVC----PLSVAGQAGCVCARVAGGGRRELGEWRRQWR
AEWELPPGPWHGGPAGLDGLDGKDGKPGMRGDPGSPGPPGLM---GPPL----------P
------------------------SLLGWM------------GRPPG--QPGPAGISAVG
LKGDRGASGERGPAGIPGQPGPPGHPGPPGEP-GTDGATG---------------KEGDP
GPTGQKGQAGEKGRSGMPGGG----HPGSPGPAGSGDYRGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDDRMAYYTSRMQFPVEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKEGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGT
TGPMGQQG------------QPGKAGHCNPSDCFGAMPMEEQYPPMKNTKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPMRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAPLTGRISQKAE
RRAKVEVGVW------RTPLPCVHG---AQDSNLPF-WFH---------------SQGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPEAPLQCAEGPKGEKGESGALVSVGPGIGQGWWGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVPA------------RGDPGIQGIKGEKGESCLSC
SSVVGAQHLASSTGASGDVGSPGFGLPGLPVSDYF--------LPG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPCEPCPALSNLQDGDVRVVASPGPSGEKGEPGPPGFGLPGKQV
--------RWDIGDAGNPGDPGTPGITGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGPL-GRGVQGPQARRLRC----------------REVEQVAQGQ-----P
YK-----------------------------RPFVF-----VHVSQRLLYFQGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGNSWQPGP-----------------------
-----------------QVPLTR-------VSSWLQGVPGNNGLPGQPGLTAEMVG----
--------------TSQDSLSIICGDCVQGQRAHPAYLVEKGEKGDQSIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNS

PF01391 // ENSGT00900000140804_4_Domain_12 (1306, 1363)

EGDPGCVGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PVRGSWKGR----KSWGGRGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGIP---------------SPPFCRGSQRHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHV--------------------G
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDMGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPMRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAPLTGRISQKAE
RRAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPEAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVSA------------RGDPGIQGIKGEKGESCLSC
SSVVGAQHLASST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGRAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVASPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGITGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-LGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGIPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGASVSGPPGRDGQQGQTG---PKG-----TPGEKGPRGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGNSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAEMGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNSEGDPGCV

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------CPPCVHG---AQESNVTLAPSG---------------SKGET
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAEGPKGEKGASGASGPPGPPGTGGQKGQKGER-
GDGGIKGLPGRPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGIPGEPGGPPGPKGDKGSSGVPGKEGPGGKPGKPGVPGVKGEKGDPCEVCP
TLPDGFQNFVGLPGKPGPKGEPGDPAPARDALGSAGQKGDRGDPGIQGIKGEKGEPCSSC
SLVAEAQYLGPSSGS---------DLPGILEK

PF01391 // ENSGT00900000140804_4_Domain_5 (753, 800)

AGAPGPRGLKGEKG--NFGEAGPAGS-P
GPPGPVGPTGTKGEKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCSALSTPQAGSDHVVRLPGRPGEKGEPGAPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 891)

GLPGEQG
KAGER-GLKGQKGEAGNPGDPGRPGSTGRPGLSGEPGVRGPVGPKGDKG-DACTACSSLQ
GAVTDMTGLPGKP-GPRGERGPEGVGRPG----KAGKPG-------LPGVQ----GPPG-
--LKGTQGEPGP-PGVAA

PF01391 // ENSGT00900000140804_4_Domain_8 (979, 1034)

QGPQGEPGAQGLPGIQGLPGSRGPPGPAGEKGAQGP-----P
GTKGAAGLVGPPGASISGPPGE-----------------------KGSQGEKGDPGECSC
PSRGDPVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGVPGLQGLPGVDGLPGQPGLTAEVGS----
-------LP-----IERQLLKSICGDCVQGQTSIPLSPLEQGAKEDQAISGVPGLDNCAG
CFSQRERPRAEEAR---------------------------GDNNEKDFDCADSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGPAGEKGEP-GPPGSEGLPGSP
GPVGPQGERGPQGKSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGMRGP--------------------TGLP
GSTGPPGPPGIQGPAGLDGLDGKDGKPGVRGDPGPPGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGTEGEPGAMGPQGRQGPPGHIGP-PGPPG--QPGPAGISAVG
LKGDRGASGERGPAGIPGQPGPPGHPGPPGEP-GTDGATGKEGPPGKQGLHGFPGPKGEP
GPT

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1801)

GQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPQGSPGLPGVPGSM

ENSGT00900000140804_4_Linker_17_18 (1801, 1842)

GDLVNYDEIKRFIRQEIIKMFDDRMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPAGQPGKAGHCNPSDCFGAMPMEDQYPPMKNMKGPFG

---------------------------------------------------------MRV
SWIPGLWLLSLWVTFSHGANTGEMTG-----------WSGTHKPVTGFNLIRRLNLMKST
AIKKIRNPKGGPLILRLGATPLTQPTRRVFPQGLPEEFALVLTLLLKKHTYQSTWYLFQV
TDGDGYPQISLEVNSQEQSLELRAQGQDGEFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSQPLGPRRPMQPVGHVFLGLDAEQGRPVSVSAKLLH-----------GLGFY
LPCQCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPHNSKVDSKLMGRTSQQAE
RGTKV-----------EMCPPCVHG---AQESNVTLGPSS---------------SKGEP
GERGLPG-PSGPKGEKGARVSPQLCPQQAVLARPEGWGRSYLLVISEGSLGQMGVRVGLW
FLAMPGPCFSPQGNDCVRISPDAPLQVRP-------------------------------
------------------RGEACFGTKVGS----------------APXXXXGVPGLPQY
LSPSGTQLAGPPAF------------------------LPLIPPCPKP---TTLRRKNHT
LPEQGFQNFVGFPGKPGPKGEPGDPAPARLAGV-------------------AMERCCDS
I------------------------LVIFQGKAGAPGPRGLKGEKV--RNGLNQEHQRV-
----ARDLAHIFTRQGEPCEPCSALSKPQDGSSHVVHLPGQPGEKGEPGAPGFGLPGERG
KAGER-GLKGQKGDAGDPGDPGRPGTAGRPGLSGEPGVRGPEGPKGDKG-DACTACPSLQ
GAVTDMTGLPGRP-GPRGERGPEGVGRPG----KPVSCSCLPLV--LPCLCLPFVSHLVP
CGTLG-------------------PGKPGLPGVQGPPGLKGTQVCMSTAG---------P
GCSW-----------VWGRA----------------------GRAWGPEGVSGEPGECSC
PTRGDPIFS---GMPVSAFLQTLS-------LSSPPP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGLPGIDGLPGQPGLTAEVVGT---
----------S---QHTVHLPSICGDCVQDQMTNPSSLQEKGEKRDQAVSGVPGLDSCAR
CFLQRERPRAEEAR---------------------------GDNMEKDSDCVESPGLPG-
-PPGLPGQRGEEVRPGRGPPSG-----------------QGQGTQGDRGLRGLTGDKGE-
----------PGPPGSDGLPGSPGPAVSERAWGEVDMDSLVPLWALSTARLGSS-CILLL
WRQGPQGERGPQGKSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKTGAPGPPGPQAEKL----PSPTGKF---------------------RLY
QGWSV-TAGWQQGPWWTSG---------DRRTPGPG--PSLRQGQGCNDFVG-TDFQGSE
GIRGPTGLPGPPGSSGRPGAEGEPGAMGPQGRPGSPGHI------VS--QPGPAGISAVG
LKGERGASGERGPAGIPGQPGPPGHPGPPVRSHSLQHNPGEGSHL-VMLDCDFLSLKGDT

PF01391 // ENSGT00900000140804_4_Domain_17 (1741, 1795)

GPAGQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPPGNPGLP

ENSGT00900000140804_4_Linker_17_18 (1795, 1842)

GVPGSM
PS-----TCARFIRQEMIKMFDDRMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPAGQPGKAGHCNPSDCFAAMPMEEQYPSIKNVKGPFG

---------------------------------------------------------MLA
SWAPGLWLLGLWATFSHGTNTGERCPASQQEGLKLEHSSDPSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAVPLTQPTRRVFPRGLPEEFALVLTVLLKKHTFRNTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSQPLGPWQPIRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQSSKVDAQLMGRSSQKAE
RGTKAQRETEA-----DECPPCVH---GARESNVTLGPSG---------------PKGGK
GERGLTG-PSGPKGEKGARG----------------------------------------
-------------NDCVRVSPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGDLGPSGLPGSAGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGLPGIGLPGTPGDPGGPPGPKGDKGSSGTPGKEGPGGKPGKPGVPGSKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPAGEGLGVAGLKGDRGDPGIQGMKGEKGEPCSSC
SSGVGAQHLGPSP---------GY

PF01391 // ENSGT00900000140804_4_Domain_5 (745, 800)

GLPGLPGKSGVPGPKGLKGEKG--NFGDTGPAGV-P
GPPGPVGPAGTKGAKGEPCEPCAAMSKLPDGDNHVAHVPGPAGEKGEPGPPGFGLPGKQG
RAGEP-GLKGQKGDAGNPGDPGTPGTTGQPGMSGEPGVRGPAGPKGEKG-DGCTACSSLQ
GALTDVSGLPGKP-GPKGEPGPEGVGRPG----KPGKPG-------LPGVQ-------GP
PGLKGTQGEPGP-PGT

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GAEGPQGEPGAQGLPGIQGLPGPRGPPGSAGEKGAQGP-----P
GPKGATGPVGPPGASVSGPPG-----------------------EKGSRGEKGEPGECSC
ASRGEPIFS---GMPGAPGL----W---MGSSSQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGNCAQGQTAHPAFLLEKGEKGDQGIPGVPGFDNCAR
CFTGRERPRAEEARG---------------------------DNSEGEPGCPGNPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPI---------------GLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGPAGEKGES-GPPGSEGLPGPQ
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPIGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHLGP----PG--QPGPPGISTMG
PKGDRGAPGERGLAGLPGQPGTPGHPGPPGEP-GSDGAAGKEGPPGKQGLYGPPGPKGDP
GPA

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1801)

GQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGNPGLPGLPGSM

ENSGT00900000140804_4_Linker_17_18 (1801, 1842)

GDMVNYDDIKRFIRQEIIKMFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKIGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWA
SWAPGLWLLSLCVTYSHGADAGEQCPPSQQEGLKLEHRSDLSTNVTGFNLIHRLSLMKTS
AIKKIRNPK-GPHILRLGAISVTQPTRRVFPRGLPSEFALVLTLLMKKHTHRNTWYLFQV
TDGDGYPQISLEVNSQEQSLELRARGQDGDFVSCIFSVPQLFDLHWHKLVLSMAERVASV
HVDCMSASSQPLGPWRSIQPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLSGRISQKPE
RGAKAHQETAA-----DECPPCVHG---ARESNVTTGPSG---------------PQGGK
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------SDCVRLSPDAPLQCAEGPKGEKGELGALGPSGLPGSTGQKGQKGEK-
GDGGVKGSPGKPGRDNGDTGRGGLCPRRGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLQGTPGDPGGPPGPKGDKGSSGVPGKEGPGGKPGKPGVPGLKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPA------------RGDPGIQGLKGEKGESCSSC
SFAVAAQHLQPSA

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 797)

GAKGDMGPPGLGLPGLPGKAGAPGPTGLKGEKG--NFGEVGPAGS-P
GPPGPAGPTGIKGEKG

ENSGT00900000140804_4_Linker_5_6 (797, 820)

EPCEPCRALTEHQDEDSHVVALP

PF01391 // ENSGT00900000140804_4_Domain_6 (820, 871)

GPRGEKGEPGPPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPVGPKGEKG-DGCTACPGLQ
GALTDRAGLPGKP-GPKGDPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGIQGEPGP-PGV

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGDPGAQGLPGIQGLLGPRGPPGPAGEKGAKGS-----P
GVKGATGPMGPPGASVSGPPGPDGHQGQTGLPGARG-----MPGEKGSQGEKGEPGECSC
PSRGDPIFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1190)

GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPG

ENSGT00900000140804_4_Linker_10_12 (1190, 1333)

LTAELGS----
-------LP-----IEQHLLKSICRDCIQGKMAHEVALLESGEKGDQGIPGVPGLDSCAQ
CWAPGHSSLAEGAV--------------------------------------ESPGAASS
EPLHLFPWLPSQ

PF01391 // ENSGT00900000140804_4_Domain_12 (1333, 1402)

GPPGMRGSPGRRGRKGPPGFPGAVGSPGLPGLQGERGLRGLTGEKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGSPGEKGES-GPPGSEGLPGPP
GPAGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PAGFPGKAGAPGPPGPPAEKG----SEGIRGP--------------------SGLP
GPPGPPGSPGIQGPAGLDGLDGKDGKPGMRGDPGPAGPPGLM---GPPGFKGKPGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
PKGDRGATGERGLLGLPGQPGPPGHPGPPGEP-GMDGAAGKEGPPGKQGLYGPPGPKGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMRFPMEMVAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGPPGRPGSP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1898)

GVGI

PF01391 // ENSGT00900000140804_4_Domain_19 (1898, 1947)

AGEIGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGPPGKTGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWT
SWIPGLWLLSLWVTFSHGANTERQCPPSQQEGLKLEHSSDLSANVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGATPLTQPTRRVFPRGFPEEFALVLTLLLKKNSPQNTWYLFQV
TDGEGYPQISLEVNSQEQSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCVSASSQPLGPRRPVRPLGHVFLGLDSEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPAGCPPESSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQHSKVDAQVMGRIRQKTD
METKVHRETSA-----DECPPCIPA---VGETNVS---------------------ENGK
GEQGPPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRVSPDAPLQCSE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 580)

GPKGEKGTAGALGPLGPPGSTGQKGQKGEK-
GDGGIKGLPGKPGRDGRP-GEICVIGPKGQ---------

ENSGT00900000140804_4_Linker_1_2 (580, 617)

KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPG

PF01391 // ENSGT00900000140804_4_Domain_2 (617, 658)

GPAGPKGNKGSPGTPGKEGPSGKPGKPGVPGTKGNKGEPCEVCP
TLPEGFQNFVGLPGKTGPKGEPGDPAPA------------GGDPGIQGIKGEKGEPCLAC
SSVVEAQHLRDAGSA------------GLPVKADIP----SLHPGG-

PF01391 // ENSGT00900000140804_4_Domain_5 (768, 798)

-NLGETGPAGN-P
GLPGPVGPAGAKGAKGE

ENSGT00900000140804_4_Linker_5_6 (798, 822)

PCELCSGLSMTQDGNGHVVALPGP

PF01391 // ENSGT00900000140804_4_Domain_6 (822, 898)

TG----------------G
KAGER-GLKGQKGDAGSPGDPGMPGTVGQPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GAMTDMMGLPGRP-GPKGEQGPEGVGQPG----KAGQPG-------LPGVP----GPPG-
--LKGTQGEPGP-PGMGAQGPQXXXXXXXXXXXXGLPGPQGPAGPAGEKGDQGA-----P
GVKGSIGPAGPPGASVS

PF01391 // ENSGT00900000140804_4_Domain_9 (1038, 1077)

GPPGRDGLQGQMGSPGVRG-----TPGEKGSQGEKGEPG

ENSGT00900000140804_4_Linker_9_10 (1077, 1115)

ECSC
PYRGEPVFS---GMPGAPGL----W---MGNSWQ

PF01391 // ENSGT00900000140804_4_Domain_10 (1115, 1188)

PGP-----------------------
-----------------QGPPGVPGPPGPPGAPGLQGVPGNNGLPGQ

ENSGT00900000140804_4_Linker_10_12 (1188, 1305)

PGLTAELGV----
-------SAPL---ARNGVFPSICGNCAQAQVAHSVSFLEKGEKGDQGIPGVPGLDNCAR
CFSERERPRAEEAR---------------------------GDN

PF01391 // ENSGT00900000140804_4_Domain_12 (1305, 1365)

GEGEPGCAGSPGLPG-
-PPGLPGQRGEEGPPGMRGAPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGLSGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGHSGPAGEKGEP-GPPGSEGLPGPQ
GPVGPRGERGPQGTSGQKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGMRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGEPGPAGSPGLM---GPPGFKGKPGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAMG
LKGDRGATGERGLMGLPGQPGPPGHPGPPGEP-GTDGADGKEGPPGKQGLYGPPGPKGDP
GPAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIVKMLDERMAYYTSRLQFPME

PF01391 // ENSGT00900000140804_4_Domain_18 (1838, 1896)

MVAAPGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGVPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------CPPCVHG---AQESNVTLGPSS---------------SKGEP
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAEGPKGEKGASGASGPSGLPGPGGQKGQKGEK-
GDGGIKGLPGRPGRDGRP-GELCVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGLPGMGLPGTPGEPGGPPGPKGEKGSSGVPGKEGPAGKPGKPGVPGVKGEKGNPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPARDAMESTGRKGDRGDPGIQGIKGEKGEPCSSC
SLVAEAQFLGPSSG---------SSLP

PF01391 // ENSGT00900000140804_4_Domain_5 (748, 800)

GLLGKAGAPGPRGLKGEKG--NFGEAGPAGD-P
GLPGPVGPAGTKGQKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCSALSKPQDGSSHVVHLPGQPGEKGEPGAPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 891)

GLPGERG
KAGER-GLKGQKGDAGDPGDPGRPGTAGRPGLSGEPGVRGPEGPKGDKG-DACTACPSLQ
GAVTDMTGLPGRP-GPRGVRGPEGVGRPG----KPGKPG-------LPGVQ----GPPG-
--LKGTQGEPGP-PGM

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GAQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGP-----P
GTKGATGLVGPPGASISGPPGE-----------------------KGSQGEKGEPGECSC
PTRGDPIFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGLPGIDGLPGQPGLTAEVGS----
-------LP-----IERQLLKSICGDCVQDQMTNPSSLQEKGEKRDQAVSGVPGLDSCAR
CFLQRERPRAEEAR---------------------------GDNMEKDSDCVESPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGDRGL

PF01391 // ENSGT00900000140804_4_Domain_12 (1371, 1433)

RGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGPAGEKGEP-GPPGSDGLPGSP
GPAGPQGERGPQGKSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKTGAPGPPGPQAEKG----SEGIRGP--------------------TGLP
GPPGPPGPPGIQGPAGLEGLDGKDGKPGVRGDPGPPGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGSPGHIGP-PGPPG--QPGPAGISAVG
LKGERGASGERGPAGIPGQPGPPGHPGPPGEP-GMDGATGKEGPPGKQGLHGFPGPKGDT
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPPGNPGLPGVPGSM
GDLVNYDEIKRFIRQEMIKMFDDRMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPAGQPGKAGHCNPSDCFAAMPMEEQYPSIKNVKGPFG

---------------------------------------------------------MLA
SWAPGLWLLGLWATFSHGVNIGEQCPSSQQEGLKLEHSSDPSTNVTGFNLIRRLNLMKIS
AIKKIRNPK-GPLILRLGAAPLTQPTRKVFPWGLPEEFVLVLTVLLKKQTFRNTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSQPLGPWQPIRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLMGRSSQKAE
RGTKVDGGGGRSSQCPLSCPPCVHS---ARESNVS-------------------GWGGGK
GERGLTG-PSGPKGEKGARV----------------------------------------
-------------STQTKST-SGPLPLERSLVGCKLTSHHLRTVLVTCIFLPQ

PF01391 // ENSGT00900000140804_4_Domain_1 (534, 602)

GQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGLPGIGLIPTPL-----------------------------------FLSQGCRLEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPA------------RGDPGIQGMKGEKGEPCSSC
TSGVGAQHLS------EDPGSSGHGLPGLPGKSGVSGPRGLKGEKVSPG--DTGSRGD--
---SPERQVSIFALQGEPCEPCAALSRLPDGDSHVVHLPGPAGEKGEPGPPGFGLPGKQV
NSGISGGGCGQDGDAGNPGDPGTPGTTGQPGMSGEPGVRGPAGPKGEKVSG-----PSLE
EF----VALANRNQGVSNEGEPQG-SPAG-----------------EPGAQ-------GL
PGIQVGFLWPGG-DN------------QLGFHLQGLPGPRGPPGSAGERGAQVS-----P
FFCGCWGCRHG----------------DLGLSD---------------------------
-------------------S----S---RGFSSQPGPQVCVACLLCLASCRGFPALTLLP
SPVAGSSHPPLILSSLPQGPPGVPGPPGPPGLPGLQGLPGHNGLPGQPGLTAELVG----
-------IS-----QD---TLSICGNCAQAQTAHPAFLLEKGEKGDQGVPGVPGFDNCAR
VGTGQRRAA-------------------------------MGDNSEGEPGCPGNPGLPG-
-PPGLPGQRGEEGLEDIGS---------------------TSGLQGERGLTGLTGDKGE-
----------PVRKGP-RIPAAMA--------EGW---PLSGRWGES-RSPD------A

PF01391 // ENSGT00900000140804_4_Domain_13 (1440, 1525)

E
GLGGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLEGLDGKDGKPGLRVRWGWGV-----------GWAGPL--PNLL
--LIKCAEKSPLHQGGHLL---APGTWW-WGLGSASGLVGS-AS--P--FPAHFHPIFQG
LKGDRGAPGERGLAGLPGQPGTPGHPGPPG-------------PPGKQGLYGPPGPKGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGNPGLPGLPGSM
GDMVNYDDIKRFIRQEIIKMFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MPSV--------
----------------------------------------------STRSCTPTVPVPGS
TLKKVLDRTGSV-PSS-----------Y---------------HSAERGMLCK-------
-------------------DRSFWGSGVEYIQQNWGWKPLVLTSSN---------HQNPA
----PRA-----------------------------SSPTGEG-----------------
----LGGGVGKALLTVLWGSAPFQG----SEGIRGP--------------------PGMP
GPPGPPGSPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHIGP-PGPPG--QPGPAGISAVG
LKGDRGAPGERGMLGLPGQPGTPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGPKGDP
GPS

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1802)

GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
G

ENSGT00900000140804_4_Linker_17_18 (1802, 1842)

DMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1893)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGVPGMRGLPGTKGEKGDVGIGMAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
PWVLGLWLLNLWGTFSHGANTGEQCPPSQQEGLKLEHSSDLSANVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGTAPLTQPTRRVFPRGLPEEFALVLTLLLKKHTHQNTWYLFQV
TDGDGYPQISLEVNSQEQSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCLSASSQPLGPRRSTRPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQPTGRISQKAE
RGAKIHRETAA-----DECPPCVHG---AQESNVTLGPSG---------------PKGGK
GDQGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 561)

GPKGEKGESGALGPSGLPGSIGQKGQKGER-
GDGGIKGLPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGTGLPGTPGDPGGPPGPKGDKGSSGMPGKEGPGGKPGKPG---MKGEKGDPCEVCP
TLPEGFQNLVGLPGKPGPKGEPGDPAPA------------RGDPGIQGIKGEKGESCLSC
SSVVGAQHLGSSAGASGDVGSPGFGLPGLPGKAGVPGPTGLKGEKG--SSGEAGPAGS-P
GPPGPVGSAGIKGAKGEPCEPCLALSGPQDGGIHAVALPGPAGEKGEPGSPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KPGER-GLKGQKGDSGNHGDPGIPGTMGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GALTDLPGLPGRP-GPKGDQGLEGVGRTG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGAPGARGLPGTQGLPGPQGPPGRTGEKGAQGS-----P
GLKGAIGPMGPPGASISGPPGRDGQQGQTGLSGARG-----MPGEKGSRGEKGEPGECSC
PSRGDPIFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCGQGQMAYPASILEKGEKGDQGIPGVPGFDNCAR
CFAERERPRAEEAR---------------------------GDNSEGDPGCAGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYVGPAGEKGES-GPPGSEGLPGSP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GPPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGLQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGIPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGPKGDP
GPS

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1802)

GQKGQAGEKGRSGMPGGPGKSGSMGPAGPPGPAGERGHPGSPGPTGSPGLPGVPGSM
G

ENSGT00900000140804_4_Linker_17_18 (1802, 1842)

DMVNYDEIKRFIRQEITKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGTPGRPGSP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGVGITGESGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGPPGKTGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

------------------------------------------------------------
---------------------GGQCPPSQQEGLKLEYRSDLSTNVTGFNLIHRLNLLKTS
AIKKIRNPK-GPLVLRLGATALTQPTRRVFPRGLPDEFALVLTLLLKKHTHQSTWYLFQV
TDGDGYPQISLEVNSRERSLELRARGQDGDFVSCVFPVPQLFDLRWHKLVLSVAERVASV
HIDCTSASSQPLGLRRPVQPVGHVFLGLDSEQGKPVLFDLQQAHIYCDPELVLEEGCCEI
VPGGCPQETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQSSKVDTHLTGRISQKAE
RGTQAHRETEA-----HECPPCVPG---AQESNVTIGPSG---------------PKGGK
GERGLPG-PSGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGEAGALGPSGHPGSTGQKGQKGEK-
GDEGIKGLPGKPGRDGRP-GEICVMGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGRGLPGTPGDPGGPAGPKGDKGSSGAPGKEGPGGKP--PGVPGLKGEKGDPCEVCP
TLPEGFQNFMGLPGKPGPKGEPGDPAPA------------RGDPGIQGLKGEKGESCLSC
SLAVGAQHLEPSTGAKGDVASPGF

PF01391 // ENSGT00900000140804_4_Domain_5 (745, 798)

GLPGLPGKVGAPGPTGLKGEKG--DFGEAGPAGS-V
GPPGPVGPAGIKGEKGE

ENSGT00900000140804_4_Linker_5_6 (798, 834)

PCELCPALSEPQDGAGHMVALPGPPGEKGEPGLPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGSMGQPGLSGEPGVRGPTGPKGEK

ENSGT00900000140804_4_Linker_6_7 (889, 908)

G-DGCTACPSLQ
GALTNIA

PF01391 // ENSGT00900000140804_4_Domain_7 (908, 975)

GLPGKP-GPKGEPGPEGVGRPG----KPGKPG-------LPGVQ----GPPG-
--LKGTQGEPGP-PGMGVQGPEGEPGAQGLPGVQGLPGPRGPPGPTGQKGAKGF-----P
GVKGAIGPVGPPGASVSGPPGAEGQRGQTGLPGARG-----MPGEKGSQGEKGEAGECSC
PSR-DLVFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1190)

GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGVPGLQGVPGNNGLPGQPG

ENSGT00900000140804_4_Linker_10_12 (1190, 1313)

LTAELGS----
-------LP-----IEQHLLKSLCGDCVQGQTALPAALLEKGEKGDRGIPGVPGFDSCAR
CFAERERPRAEEAR---------------------------GDNNEGDPDCV

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1373)

GSPGRPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGPTGEKGE-
----------PGPAGQPGYPGAMGPPGLPGIKGERGYAGAPGEKGES-GPPGSEGLPGPV
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKE----AEGCKGS--------------------LKTP
GLPAQMPFSGFQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-P-PPG--QPGPAGISVVG
LKGDRGPTGERGLLGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGLPGPKGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMVAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1898)

GIGI

PF01391 // ENSGT00900000140804_4_Domain_19 (1898, 1947)

AGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPADCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANAGEQCPLSQQEGLKLEHSSGLSANVTGFNLIRRLSLLKTS
AIKKIRNPK-GPLILRLGAAPLTQPTRRVFPRGLPEEFALVLTLLLKKHTHQNTWYLFQV
TDGDGYPQISLEVNSHERSLELRARGEDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSQPLGPRRPTKPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLTRRTSQKAE
RGAKAPREAAG-----DECPPCVPG---AQESNVTLGPSG---------------PKGGK
GEQGPPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---AKGEKGDPCEVCP
TLPEGFQNIVGLPGRPGPKGEPGDPAPA------------RGIQGIQGIKGEKGEPCSSC
DIVAGALHLRPSAGASGEVGSPGFGLPGLPGKPGAPGPTGLKGEKG--NLGPAGTAGG-P
GPPGPAGPAGVKGAKGEPCEPCAALSSPQDGDVRVVALPGPAGEKGEPGAPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTMGQPGLSGEPGVRGPVGPKGEKG-DGCTACPSLQ
GAQTNMAGLPGKP-GPKGDQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGIQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1033)

GAQGPQGEPGAQGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGAMGPVGPPGAGVSGPPGRDGQQGQSGLPGARG-----MPGEKGSQGEKGEPGECSC
PSRGDPVFS---GMPGAPGL----W---MGNSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCAQGQLTHPASLLQKGEKGDQGIPGVPGLDSCAG
CFSERERPRAEEAR---------------------------GDNINGDADCP

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGPTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYSGPAGEKGES-GPPGSEGLPGPT
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGMRGP--------------------AGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAMG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GADGAVGKEGPPGKQGLYGPPGLKGDP
GSPGQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCTPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLVLWATFSHGANAGEQCPPSHQEGLKLEYSSSLSANVTGFNLIRRLSLMKIS
AIKKIRNPN-GPLILRLGATPLTQPTRRVFPRGLPEEFALVLTLLLKKHTYQNTWYLFQV
TDGSGYPQISLEVNSQEQSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSQPLGPWKRTKPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQNSKVDTQLTGRISQKAE
RGAKAHRESAA-----DECPPCVHD---ARESNVTLGPSG---------------PKGGK
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGDLGPSGLPGSIGQKGQKGEK-
GDGGTKGFPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGR
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPA------------RGIQGIQGIKGEKGEPCLSC
STVVGAQHLESST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 798)

GASGDVG-----FPGLPGKPGAPGLMGLKGEKG--NLGAAGPAGH-P
GLPGPAGPAGIKGAKGEPCEPCPGLSSSQDGDVRVVALPGPAGEKGEPGPPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGSMGRPGLSGGPGVRGPVGPKGEKG-DGCTACPSLQ
GALTDMAGLPGKP-GPKGDQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGIQGEPGP-PGM

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GAEGPQGEPGAQGLPGIQGLRGPQGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGANVSGPPGRDGQPGQSGPPGAKG-----MPGEKGSRGEKGEPGECSC
PSRGDPIFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1190)

GMPGAPGL----W---MGNSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQYLLKSICRDCVQGQVAHPASLLEKGEKGDQGIPGVPGLDSCTW
CFSERERPRAEEAR---------------------------GDNNEGDPGCAGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGLPGPIGPPGFPGAVGSPGLPGLQGERGPPGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYVGPAGEKGES-GPPGSEGLPGSP
GPAGPRGERGPQGNSGEKGDQGF--------Q

PF01391 // ENSGT00900000140804_4_Domain_13 (1473, 1576)

GQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------TGMP
GPPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGSAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGSPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHIGP-PGPPG--QPGPAGISAMG
LKGDRGATGERGLAGLPGQPGSPGHPGPPGEP-GADGPAGKEGPPGKQGLYGPPGPKGDP
GPAGLKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGLPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGTPGRPGSP
GAPGLPGQIGREGRQGLPGMRGLPGTKGEKGDT

ENSGT00900000140804_4_Linker_18_19 (1894, 1896)

GV

PF01391 // ENSGT00900000140804_4_Domain_19 (1896, 1946)

GIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MLA
PWAPGLWLLGLWATFSHGTNIGERCPTSQQEGLKLEHSSDPSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGTAPLTQPTRRVFPRGLPEEFALVLTVLLKKHTFRNTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCVSASSQPLGPRQPIRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETTKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVGELGKHKGT----
----------------------------PDLAEVTLGPSG---------------PKGGK
GERGLTG-PSGPKGEKGERG----------------------------------------
-------------SDCVRVSPDAPLEVRLGGEASRSLA----------------------
------------------------ERSGRK-------TKMGDPGFVGPEGLAGEPGPPGL
PGLPGIGLPGTPGDPGGPPGPKGDKGSSGTPGKEGPGGKPGKPGVPGTKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPARVS-------------------AQAGEPCSSC
SSG-----------VNEDLGSPGHGLPGLPGKSGVPGPRGLKGEKVSPELGDTGKAGE-T
GPPGPVGPAGTKGAKGEPCEPCAALSKLPGGESHVVHLP

PF01391 // ENSGT00900000140804_4_Domain_6 (820, 877)

GPAGEKGEPGPPGFGLPGKQG
RAGER-GLKGQKGDAGNPGDPGLPGTNGHPGISGEPGVRGPAGPKGEKG-DGCTACSSLQ
GALTDAAGLPGKP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ-------GP
PGLKGTQGEPGP-PGTGAEGPQGEPGAQGLPGIQVGLLW---------------------
-------PGGNVAYNL-------------------------------------------S
PS--FATPT---PTQGAPGL----W---MGSSSQPGPQVCVA------------------
----WSSLPSLTLCSLPQGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCAQGQTAHPAFLLEKGEKGDQGIPGVPGFDNCAR
VGTGQRRAGT--------------------------------------GGFPGVGGL---
----------------------------------------------------------P-
----------GGPPGQPGYPGAMGPPGSEGLPGPQGPAVSHGVVCVA-GEPP-----GP-
--F--LCPEDWEMGSGEKGDPVSDEQGREMKHIEKGGDGPLLG-----------------
---

PF01391 // ENSGT00900000140804_4_Domain_13 (1504, 1586)

-PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGTEVRTGVLCITAVT---QPWGP-QGPPG--QPGPPGISTMV
RGQGVRSMRQG---------------WMTGEP-GSDGA---------------AGKEGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGLPGSM
GDMVNYDDIKRFIRQEIIKMFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MGPKGQ---------KGDPGFVGPEGLAGEPGRPGL
PGPPGIGLPGTPGDPGGPPGRKGDKGSSGIPGKDGPGGKPGKPGVPGLKGEKGDPCEVCP
TLPEGLQNF

PF01391 // ENSGT00900000140804_4_Domain_4 (670, 716)

VGLPGKPGPKGEPGDPAPFKERQGTVGQKGDRGDPGIQGIKGEKGE

ENSGT00900000140804_4_Linker_4_5 (716, 745)

PCLSC
SSAVGAQQLRSFTGTEGDVGIPGF

PF01391 // ENSGT00900000140804_4_Domain_5 (745, 798)

GLPGLPGKVGAPGPRGLKGEKG--NFGEAGPAGS-P
GQPGPVGPAGIKGEKGE

ENSGT00900000140804_4_Linker_5_6 (798, 834)

PCEPCLALSESQDGEGRVVALPGPSGEKGEPGSPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKPG
KAGER-GLKGQKGDAGNPGDPGTPGTMGQPGLSGEPGIRGPAGPKGEKG-DGCTACPSLQ
GAVAGMAELPGKP-GPKGDQGPEGVGRPG----KPGKPG-------LPGVP----GPPG-
--LKGSQGEPGP-PGM

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GAQGSQGEPGAQGLPGIQGLPGPRGPPGPTGEKGAKGS-----P
GLKGAMGPGGPPGASVAGPPGRDGQQGQTGLPGARG-----VTGEKGSRGEKGEPGECSC
PSRGDPIFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1191)

GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGNNGLPGQPGRTAELGS----
-------LP-----IEQQLLKSICGDCVQGQTAHPVSIVEKGEEGDQGIPGVPGHDNCVR
CFTERERPRAEEAR---------------------------GDNHEGDPGCAGSPGLPG-
-PPGLPGQRGEEGPPGVRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYVGPAGEKGES-GPPGSEGLPGPT
GPVGPRGERGPQGNSGEKGDQGF--------Q

PF01391 // ENSGT00900000140804_4_Domain_13 (1473, 1576)

GQP-GFPGPPG-----------------
----PSGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GPPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGLAGPPGIM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHLGP-PGPPG--QPGPAGISAVG
LKGDKGATGERGLGGLPGQPGPPGHPGPPGEP-GMDGAAGKEGPPGKQGLYGLPGSKGDP
GPAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPVGERGHPGSPGPAGSPGLPGMPGSM
GDMVNYDEIKRFIQQEIIKMFDERMAYYTSRMQFPVEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGSPGRPGAP
GSPGLPGQIGREGRQGVPGMRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1896)

GV

PF01391 // ENSGT00900000140804_4_Domain_19 (1896, 1946)

GIAGESGLPGPPGPQGPPGYGKMGP
TGPMGQQGIPGIPGPPGPTGQPGKTGHCNPSDCFGAMPMEEQYPPMKNMKGPFG

---------------------------------------------------------MWA
SWAPGLCLLGLWTTFSHGANPGEQCPSSQQEGLKLEHSSDLSANVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAASLTQPTRRVFPRGLPEEFALVLTVLLKKHTFQNTWYLFQV
TDADGYPQISLEVNSQERSLELRARGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASM
HVDCISASSQPLGPRRPMGPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQMEGKVYTRCFCLEEPQNSKVDAQLMGRSSQNTE
RQTKVEMVGGG------RSPWCSLSAPSLREDTALLFSSCLDRAGLCDASSERENRWGGT
DSAGLSL--------ESCRA----------------------------------------
-------------GPGPFSTPSLPIQCTEGPKGEKGEKGR--------------------
GDGGLEGSCFSPS-------WS-CPGQKGE-------KGDGDPGFVGPEGLAGEPGPPGP
PGLPGIGMPGTPGDPGGSPGPKGDKGSSGIPGKEG---KPGKPGVPGTKGEKGDPCEVCP
TLPEGFQNFLGLPGKPGPKGEPGNPAPATVS--------ALGDPGIQGMKGEKGEPCSSC
SSGVGAQQLGPATGLDGDLGSPGYSVSGLSLG---------------------ILVAI-L
GPPGPVGPAGSKGAKGEPCEPCAVLSKLQNGDSHIVHLPGPAGDKGEPGPPGFGLPGKQV
SSEKG-AVL--------------PCVSGLPEQKGKVGLGEGLSAHRSQGGNLSPAGP--S
PILLELYSLQ---------------GDAG----NPGDPG-------MPGTL-------GQ
P------------------------------GLSGEPGARGPVGPKGEK-VGGP-----P
GSKGDTGPMGPPGASVSGPPG-----------------------EKGSRGEKGEPGECSC
PSRGDPIFS---GMPGAPGL----W---MGSSSQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGMPGINGLPGQPGLTAELGS----
-------LP-----IEQHVLKSICGDCAQGLTARIAIPLEKGEKGDQGVPGVPGLDNCAR
CFTDRERPRAEEARVSKPLPS-LIP-------------PSLLHNGE

PF01391 // ENSGT00900000140804_4_Domain_12 (1307, 1412)

GEPGCPGSPGLPG-
-PPGLP---------------------------------------GERGLMGLTGDKGQ-
----------PGPPGQPGYPGAMGPPGLPVSKGTLTSWGTRGT-GWW-SGQGSEGLPGPQ
GPAGPRGERGPQGNTGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPPGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSNGRPGAEGEPGAMGPQGRPGPPGHLGP-PGSPG--QPGPPGMSTAG
LKGDRGAPGERGVAGLPGQPGTPGHPGPPGEP-GSDGAAGKEGPPGKQGLYGLPGPKGDT
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDVVNYDDIKRFIRQEIVKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGGTRSS---------------VDADLSPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPTGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWA
YWAPGLWLFGLWATCSHGAQTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXRVFPRGLPHEFALVLTLMLKKHTPQSTWYLFQV
TDGDGYPQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFDLQPEHVYCDPELVLEEGCCEI
SPDGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSQVDAQLSGRISQKTD
RGAKAHRGTAADEXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XX--------X----
------X-XXXXXXXXXXXX----------------------------------------
-------------XXXXXXXXXXXXXCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 580)

GPKGDKGESGALGPSGLPGSVGQKGEKGSK-
GDGGVKGLQGRPGRDGRP-GEICVIGPK---------GQ

ENSGT00900000140804_4_Linker_1_2 (580, 617)

KGDPGFVGPEGLAGEPGPPGL
PGPPGVGLPGTPGDPG

PF01391 // ENSGT00900000140804_4_Domain_2 (617, 658)

GPPGSKGDKGSSGTPGKEGPDGKPGRPGVPGLKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPA------------RGDPGLQGFKGEKXXXXXXX
XXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXSSV

PF01391 // ENSGT00900000140804_4_Domain_5 (771, 801)

GHAGPAGS-P
GLPGSVGAAGTKGEKGEPCGPCAALSKPQNGDDHVVGLPGPSGEKGEPGPPGLGLPGKPX
XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXVRGPPGLKGEKG-DGCTACPDRP
GAVPGTFGRPGQP-GPRGEPGPEGVGRPG----KPGQPG-------LPGVQ-------GP
PGLKGMQGEPGT-PGMGAE

PF01391 // ENSGT00900000140804_4_Domain_8 (980, 1046)

GPQGEPGAQGLPGIQG---PRGPPGPSGEKGAKGP-----P
GVKGATGPAGPPGASAPGPAGRDGQ

ENSGT00900000140804_4_Linker_8_10 (1046, 1115)

HGXXXXXXXXX--------XXXXXXXXGEAGECSC
PSRGDPVFS---GMPGAPGL----W---MGSSWQ

PF01391 // ENSGT00900000140804_4_Domain_10 (1115, 1188)

PGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGMPGNNGLPGQ

ENSGT00900000140804_4_Linker_10_12 (1188, 1307)

PGLSELXXX----
-------XX-----XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
CFMERERPRAEEARG---------------------------DTSE

PF01391 // ENSGT00900000140804_4_Domain_12 (1307, 1346)

GEPGCAGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIXXXXXXXXXXXXXXXGLQGERGLRGLTGDKGE-
----------LGPPGQPGYPGAMGPPGLPXXXXXXXXXXXXXXXXXX-XXXXXXXX----
-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXG-----------------
----PSGFSGKAGAPGPPGLQAEKG----SEGTRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGQPGPPGSSGRPGTEGEPGSVGPQGRPGPPGHLXX-XXXXX--XXXXXXXXXXG
PKGDRGATGERGLSGIPGQPGSPGHPGPPGEP-GSDGAAGKEGPPGKQGLYGLPGPKXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPGPTESPGMPGVPGSM
GDTVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPVEMAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1841, 1899)

APGRPGPPGKDGVPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGESGLPGPP-------------
------------------------------------------------------

---------------------------------------------------------MLT
SWAPGLWVLGLWATFSHGTNIGERCPTSQQEGLKLEHSSDPSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTVLLKKHTFRNTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCVSASSQPLGPRQSIRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKSRRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLMGRNIQKAE
RGTKVHQGTGV-----NECPPCAH---SARESNVTLGPSG---------------LKGGK
GERGLTG-PSGPKGEKGARG----------------------------------------
-------------NDCVRVSPDAPLQCVE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 561)

GPKGEKGESGDLGPPGLPGPTGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGEKGSSGIPGKEGPGGKPGKPGVPGTKGEKGDPCEVCP
TLPEGSQNFVGLPGKPGPKGEPGDPAPAWEGLGTVGLKGDRGDPGIQGMKGEKGEPCSSC
SSGVGAQHLGPS---------PGH

PF01391 // ENSGT00900000140804_4_Domain_5 (745, 801)

GLPGLPGTSGIPGPRGLKGEKG--SFGDTGPAGV-P
GSPGPVGPAGIKGAKGEPCEPCTALSELQDGDMRVVHLPGPAGEKGEPGSPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKG-DGCTACPSLQ
GALTDVSGLPGKP-GPKGEPGPEGVGHPG----KPGQPG-------LPGVQ-------GP
PGPKGTQGEPGP-PGT

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1033)

GAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGS-----P
GPKGAIGPMGPPGAGVSGPPG-----------------------QKGSRGEKGEPGECSC
PSRGEPIFS---GMPGAPGL----W---MGSSSQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGS----
-------LP-----IEKHLLKSICGDCAQGQTAHPAFLLEKGEKGDQGIPGVPGFDNCAR
CFIERERPRAEEARG---------------------------DNSE

PF01391 // ENSGT00900000140804_4_Domain_12 (1307, 1392)

GEPGCSGSPGLPG-
-PPGMPGQRGEEGPPGMRGSPGPPGPI---------------GLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGPSGEKGES-GPPGSEGLPGPQ
GPAGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHLGP----PG--QPGPPGLSTVG
LKGDRGVPGERGLAGLPGQPGTPGHPGPPGEP-GSDGAAGKEGPPGKQGLYGPPGPKGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGNPGLPGLPGSM
GDMVNYDDIKRFIRQEIIKLFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKSMKGPFG

---------------------------------------------------------MWV
SWLPGLWLLSLWAACSQAADTGEQCPLSQEEGLKLEHRSHLSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAAPLTQPMRRVFPRGLPSEFALVLTLLLKKHTHQHTWYLFQV
TDGDGYPQISLEVNSQERSLELRARGQDGDFVSCIFPVPQLFDLRWHKLVLSVAERVASV
HVDCTSASSRPLGPRRPMRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLTGSISQKEE
RGTKARQEPAA-----NECPPCVHG---ARESNVTVGPSG---------------PKGGK
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------SDCVRVSPEAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSAGQKGQKGEK-
GDGGIKGSPGKPGRDGRP-GEICVMGPKGQ---------KGDPGFVGPEGLAGKPGPPGH
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGVPGKEGPGGKPGKPGVPGLKGEKGDPCEVCP
TLPEGFQNFMGLPGKPGPKGEPGDPAPAKEGLGAVGWKGDRGDPGIQGPKGEKGDSCSSC
SLAVGAQHLGPSTGAK

PF01391 // ENSGT00900000140804_4_Domain_5 (737, 797)

GDVGSPGFGLPGLPGKTGAPGPAGLKGEKG--NFGEAGPAGR-Q
GPPGPAGPTGTKGEKG

ENSGT00900000140804_4_Linker_5_6 (797, 834)

EPCEPCPALSKPQDEDGYVVALPGPPGDKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
RAGER-GLKGQKGDAGNPGDPGVPGTMGQPGLSGEPGVRGPVGPKGEKG-DGCSACPSLQ
GAVTNAAGLPGKP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGIQGEPGS-PGK

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GAQGPQGEPGVQGLPGIQGFPGPRGPPGPTGEKGAKGS-----P
GLKGAAGPMGPPGASVSGPP-----------------------GEKGPQGEKGEPGECSC
PSRGDPIFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1190)

GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGLPGNTGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQTAHPVGLLEKGEKGDQGIPGVPGLDSCAR
CFAERERPRAEEAR---------------------------GRQREGDPGCAGSPSLPG-
-LQGLLGQRGEEGPPGMRGSPGPPGPIG---------------LQGERGLRGPTGEKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYIGPPGEKGES-GPPGSEGLPGPA
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------PGMP
GPPGPPGSPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHIGP-PGPPG--QPGPAGISAMG
LKGDRGATGERGLLGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGPKGDP
GPS

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1800)

GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGS

ENSGT00900000140804_4_Linker_17_18 (1800, 1842)

M
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGVPGMRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1898)

GIGI

PF01391 // ENSGT00900000140804_4_Domain_19 (1898, 1946)

AGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANAGEQCPPSPQEGLRLEHSSGLSANVTGFNLIRRLSLLKTS
AIKKIRNPK-GPLILRLGAAPLTQPTRRVFPRGLPEEFALVLTLLLKKHTHQNTWYLFQV
TDGDGYPQISLEVNSQERSLELRARGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSQPLGPRRPTKPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLMGRTSQKAE
RGAQAHREATG-----NECPPCVPA---AQESNVTLGPSG---------------PKGGK
GEQGPPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGQKGQKGEK-
GDGGMKGLPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGVPAPA------------RGIQGIQGIKGEKGEPCLSC
SSVVGAQHLGPSAGASGEVGSPGSGLPGLPGKPGAPGLTGLKGEKG--NLGAAGPAGG-P
GPPGPAGPAGVKGAKGEPCEPCAALSSPQDGDVRVVALPGPAGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTVGRPGLSGEPGVRGPVGPKGEKG-DGCTACPSLQ
GALSNMAGLPGKP-GPKGDQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1033)

GAQGPQGEPGAQGLPGIQGLPGPRGPPGATGEKGAQGS-----P
GVKGAAGPVGLPGAGVSGPPGRDGQQGQSGLPGARG-----MPGEKGSQGEKGEPGECSC
PSRGDPIFS---GMPGAPGL----W---MGNSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCAQGQMAHPASLLQKGEKGDQGIPGVPGLDSCAR
CFSERERPRAEEAR---------------------------GDNIDGEPDCP

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGPTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGPAGEKGES-GPPGSEGLPGPA
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------AGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAMG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGLKGDP
GSPGQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCAPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNNQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPWRPLRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRINQKAE
RGAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGQSGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVSA------------RGDPGIQGIKGEKGESCLSC
SSVVGAQHLASST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGKAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGMGQPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGREVQ

PF01391 // ENSGT00900000140804_4_Domain_8 (980, 1034)

GPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGASVSGPPGRDGQQGQTG---PRG-----TPGEKGPRGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNNEGDPGCIGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPP

PF01391 // ENSGT00900000140804_4_Domain_13 (1432, 1519)

GSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGLYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNNQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTHCFCLEEPQNSQVDAQLTGRINQKAE
RGAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGQSGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVSA------------RGDPGIQGIKGEKGESCLSC
SSVVGAQHLASST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGKAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGMGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGREVQ

PF01391 // ENSGT00900000140804_4_Domain_8 (980, 1034)

GPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPMGPPGASVSGPPGHDGQQGQTG---PRG-----TPGEKGPRGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNN

PF01391 // ENSGT00900000140804_4_Domain_12 (1306, 1363)

EGDPGCIGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGLYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGTQCPPSQQEGLKLEHSSSLPANVTGFNLIHRLSLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLMKKHTHQKTWYLFQV
TDANGYPQVSLEVNSQERTLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCAI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRISQKAE
RGAKVHRETAV-----DECPPCVHG---TQDSNVTLAPSG---------------PKGGK
GERGLPG-PAGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGIKGLPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPVPA------------RGHPGIQGIKGEKGEPCLSC
SSVVGAQHLVSST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 799)

GASGDVGSPGFGLPGLPGRAGVP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPAGIKGVKGEP

ENSGT00900000140804_4_Linker_5_6 (799, 834)

CEPCPALSNLQDGDIRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDMAGWPGQP-GPKGEQGPEGMGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGRG

PF01391 // ENSGT00900000140804_4_Domain_8 (978, 1035)

VQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGASVSGPPG--------------------------------EPGECSC
PSRGDLVFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1190)

GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPG

ENSGT00900000140804_4_Linker_10_12 (1190, 1313)

LTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNSEGDPGCV

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1369)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGP-
CSPGPPG-PGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1898)

GIGI

PF01391 // ENSGT00900000140804_4_Domain_19 (1898, 1946)

AGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNNQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRINQKAE
RGAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGQSGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVSA------------RGVPGIQGIKGEKGESCLSC
SSVVGAQHLASST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGKAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGMGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGVQGLPGPRGPPGRTGEKGAQGS-----P
GVKGATGPVGPPGASVSGPPGRDGQQGQTG---PRG-----TPGEKGPRGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNNEGDPGCI

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGLYGPPGPKGDP
GAAGPKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIHRLSLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRISQKAE
RGAKVHRETAA-----DECPPCVHG---ARDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGIKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPVPA------------RGDPGIQGIKGEKGEPCLSC
SSVVGAQHLVSST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGRAGVP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPAGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDMAGRPGQP-GPKGEQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGASVSGPPGRDGQQGQTG---LRG-----TPGEKGPRGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNSEGDPGCVGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGPPGPP
GPVGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGSPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLA

PF01391 // ENSGT00900000140804_4_Domain_16 (1695, 1754)

GLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQAGEKG

ENSGT00900000140804_4_Linker_16_18 (1754, 1842)

RAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFNHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRIFPRGLPEEFALVLTLLLKKHTYQKTWYLFQV
TDADGYPQISLEVNSQERSLELRAQGQDGDFVSCVFPVPQVFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSQVDAQLTGRISQKAE
RGAKVHRETAA-----DECPPCVHG---AGNSSVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGAQG----------------------------------------
-------------NDCVRISPDAPLQCAEGPKGEKGESGAL-------------------
----------------------------------------GDPGFVGPEGLAGEPGLPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGMPGKEGPGGKPGKPG---VKGEKGEPCEVCP
TLPEGFQNFVGLPGKLGPKGEPGDPAPA------------RGDPGIQGIKGEKGEPCLSC
SSVVGAQHLASSTGAGGEVGSPVFSL

PF01391 // ENSGT00900000140804_4_Domain_5 (747, 799)

PGLPGTAGAP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPAGIKGAKGEPCEPCPALSNLQDGEVRVVALPGTSGDKGEPGPPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGMPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTNMAGRPGQP-GPKGEQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGSTGEKGAQGS-----P
GMKGATGPMGPPGASVSGPPGRDGQQGQTG---ARG-----TPGEKGSRGEKGEPGECSC
PSRGDVVFS---GMPGAPGM----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNNEGDPGCVGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGSP
GPVGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP

PF01391 // ENSGT00900000140804_4_Domain_14 (1561, 1622)

GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GADGTAGKEGPPGKQGLYGPPGPKGDP
GAAGQKGQPGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGQCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNNQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRINQKAE
RGAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGQSGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVSA------------RGDPGIQGIKGEKGESCLSC
SSVVGAQHLASST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGKAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1033)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGTQGS-----P
GVKGATGPVGPPGTSVSGPPGRDGQQGQTG---PRG-----TPGEKGPRGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVLGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNNEGDPGCIGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSP

PF01391 // ENSGT00900000140804_4_Domain_12 (1360, 1430)

GLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGLYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------M---GPPGFKGKTGHPGLP
GPKGDCGQPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHIGP-PGPPG--QPGPAGISAVG
MKGDRGATGERGLVGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGPKGDP
GPAGQK

PF01391 // ENSGT00900000140804_4_Domain_17 (1747, 1801)

GQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM

ENSGT00900000140804_4_Linker_17_18 (1801, 1842)

GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEIAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1896)

GI

PF01391 // ENSGT00900000140804_4_Domain_19 (1896, 1946)

GVAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

MRKLRPNERTGVHHTAKRIRISAGHLPNFSGPVFYCEVPKLRMTPRCCGCGSSLWTKMWV
SWAPGLWLLGLWATFSHGANTGGQCPPSQQEGLKLEHSSDPSANVTGFNLIRRLSLLKTS
AIKKIRNPK-GPLILRLGAAPLTQPTRRVFPRGFPEEFALVLTLLLKKHTPQSTWYLFQV
TDGDGYPQISLEVNSQERSLELRAQGQDGDFMSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCVSASSQPLGPWRPVRPLGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLTGRISPKAD
RGAKVHRETAA-----DECPPCDKG---TGESNVTLGPSG---------------PKGGK
GEQGPPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRVSPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGAAGAVGPSGPPGSTGQKGQKGEK-
GDGGIKGLPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGNKGSPGVPGREGPGGKPGKPGVPGMKGQKGEPCEVCP
TLPEDFQNFVGLPGKPGPKGEPGDPAPIREGLGSAGQKGDRGDPGIQGIKGEKGEPCLSC
GSPVEAQHLRE-------VSSPGL

PF01391 // ENSGT00900000140804_4_Domain_5 (745, 800)

GLPGLPGKAGAPGPAGLKGEKG--NFGEAGPAGS-P
GPPGPAGPAGIKGAKGEPCEPCPVLSEPQDGVGRMVALPGPAGEKGDPGPPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGMPGTVGQPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GALT

PF01391 // ENSGT00900000140804_4_Domain_7 (905, 975)

GVAGLPGRP-GPKGEQGPEGVGRPG----KAGQPG-------LPGVP----GPP--
-GLKGTQGEPGP-PGIGAQGPQGEPGAQGLPGIQGLPGPRGPPGPTGETGAQGA-----P
GMKGATGPAGPPGASVSGPPGHAGQQGQMGHPGVRG-----MPGEKGSRGEKGEPGECAC
PHRGDPIFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1190)

GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQTARSVSLLEKGEKGDQGIPGVPGLDNCAR
CFLERERPRAEEAR---------------------------GDNSEGEPGCAGSPGLPG-
-PPGLPGQRGEEGPPGVRGSPGPPGPIGPPGFPGAVGSP

PF01391 // ENSGT00900000140804_4_Domain_12 (1360, 1429)

GLPGLQGERGLRGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYSGPAGEKGES-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDPGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGMRGP--------------------SGMP
GPPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGNPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAMG
LKGDRGATGERGLVGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGLYGPPGPKGDP
GPAGQKRAKQERR--GEPACLGGLARAAPWGLSGRQVLRGREATLGLRGQLGALDCPGCL
APWETW------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------

---------------------------------------------------------MWI
SWAPGLWLLGFWVTFSHGTVTGDKCPPSQQEGLKLEHSSDLSANVTGFSLIRRLNLMKTP
AIKKIRNPK-GPLILRLGAAPLTQPTRRVFPRGFPEEFALVLTLLLKKHTFQNTWYLFQV
TDADGYPQISLEVNSQERSLELRAQGQDGDFVSCLFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSHPLGPRRPMRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVGWQGWHK------
-----GHCPDS-----DLCPPCVH---GARESNVS----Q---------------WRGGK
GERGLPG-PSGPKGEKGAR-----------------------------------------
------------------VSPPAKSMCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGQKGESGALGPSGLPGSTGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGLKGDKVSAG------------------PGSGWGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPT------------KGDPGIQGMKGEKGEPCSSC
SLGVEAQHLVPSV

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 794)

GVSGDVGSPGSRLPGLPGDAGNPGDPGIPGTMG--QPGLSGEPGI--
-----RGPAGPKGEKVS------WMGADRN-QAEKTSGAGPEHQRSVETPRSS-------
------GMASQRA-------QGPSFLTCLPALA----HGLLAVPLSDQG-DGCTACPSLQ
GALTDVAGLPGKP-GPKGERGPEGVGRPG----KPGQPG-------LPGVQ-------GP
PGMKGTQVWPGV---------------GAGDGYIGLPGPRGPPGPTGEKGAQVS-----L
CFYQHW-PTGLLKV-LAAG------TGDPGLSDAHQ------------RVTKTPSTVCPL
PQ-GPPG-----LKGGAPGL----W---MGSSWQPGP-----------------------
-----------------QVLPC--------GLPMLMLLPVTVGRSSLPF----LIF----
-------PS-----LPQGPPGSICGDCAQSQTAQPAFLMEKGEKGDQGIPGVPGFDNCA-
-------------RG---------------------------DNSEGEPGCPGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPVSRGSWAYTGQGGVEGEP-P-----------
--RPSLGERGPQGNSGEKGDQVM--------VGGLVTSPSFPP-----------------
----TPPTSCKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHP

PF01391 // ENSGT00900000140804_4_Domain_14 (1618, 1676)

GLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHAGP-PGPPG--QPGPAGISAVG
LKGDRGAPGERGLAGLPGQPGTPGHPGPPVRP-QPRGSGQLALHCTRGGFW--EGDGGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGFPGTKGEKGDIGVGMAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPIKSMKGPFG

------------------------------------------------------------
----------------------EQCPPSQQEGLKLEHSSNLSANMTGFNLIHRLSLMKTS
AVKKIRNPK-GPLILRFGAAPLTQPTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFDLQQAHIYCDPELVLEEGCCEI
SPRGCPPETSKSRRDTQSNELIEINPQAEGKVYTRCFCLEEPQNSKVDAQRSGRISQKGE
RETKAHQEAVA-----DEXXXXXXX---XXXXXXXXXXXX---------------XXXXX
XXXXXXX-XX--X---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXX--------XXXXXXXX-
---------------XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----X
----XXXXXXXXXX-------------XX---------XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX----XXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX-X----XXXXXXXXXXXXXXXXXXXXXXXXXXXXG-

PF01391 // ENSGT00900000140804_4_Domain_5 (768, 799)

-NIGEAGPAGS-P
GLPGSVGPAGIKGEKG-P

ENSGT00900000140804_4_Linker_5_6 (799, 837)

CEPCLALSELQDGGSRVMALPGPPGEKGEPGPPSFGS-

PF01391 // ENSGT00900000140804_4_Domain_6 (837, 899)

GKLG
KAGEH-GPKGQKGDAGNPGDPGTPGTTGQPGLSGEPGVRGPAGPKGEKG-DGCT-CPS

ENSGT00900000140804_4_Linker_6_7 (899, 926)

LQ
GALTDMEGLPGKR-GPKGDQGPEGV

PF01391 // ENSGT00900000140804_4_Domain_7 (926, 1003)

GRPG----KPGKPG-------LPGVP-------GP
PGLKGVQGEPGP-PGMAVQGSQGEPGAQGLPGIQGLPGPRGPPGPTXXXXXXXXXXXXXX
-----XXXXXXXXXXXXXXXGHEGQQGQTGVPGARG-----VTGEKGSQGEKGEPGECSC
PSRGDPIFS---GMPGAPGL----W---MGTSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQXXXXXXXXXXXXXXXX--------
--------XXXXXXXXXXXXXSLCGDCAQGQMARPVSILEKGEKGDQGIPGVPGLDSCAR
CLTERERPRAEEAR---------------------------GDNNEGXXXXXXXXXXXX-
-XXXXXXXXXXXGPPGMRGSPGPPGPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXGF--------Q

PF01391 // ENSGT00900000140804_4_Domain_13 (1473, 1525)

GQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKGSEGXXXXXXXX------------------------
XXXXXXXXXXXXGPTGLDGLDGKDGKPGLRGDPGPAGPPGIM---GPPXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXGEPGAMGPQGRPGPPGHLXX-PGPPG--QSGPAGISAV

PF01391 // ENSGT00900000140804_4_Domain_15 (1680, 1709)

G
LKGDRGATGERGLVGLPGQPGPPGHPGPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
GDLVNYDEIKRFIRQKIIKMFDERMAYYTSRMQFPVEMAAAPGRPGPPGNDVSP-SPGAP
SSPGLPGPIATDRRAXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXPQGPPGY

PF01391 // ENSGT00900000140804_4_Domain_19 (1916, 1947)

GKIGP
TGPMGQQGIPGIPGPPGPTGQPGKTGHCSPSDCFGAMPMEEQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFGHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIHRLSLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAE
RGAKVHQETAA-----DECPPCVHG---ARDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGIKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPVPA------------RGDPGIQGIKGEKGEPCLSC
SSVVGAQHLVSST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGRAGVP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPAGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKG-DGCTACPSLQ
GTVTDMAGRPGQP-GPKGEQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGASVSGPPGRDGQQGQTG---LRG-----TPGEKGPRGEKGEPGECSC
PSQGDLIFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNSEGDPGCV

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGSPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWA
SWAPGLWLLSLCVTYSHGADAA-FCPPSLN--------SSSGVSLKGFNLIHRLSLMKTS
AIKKIRNPK-GPHILRLGAISVTQPTRRVFPRGLPSEFALVLTLLMKKHTHRNTWYLFQV
TDGDGYPQISLEVNSQERSLELRARGQDGDFVSCIFSVPQLFDLHWHKLVLSMAERVASV
HVDCMSASSQPLGPWRSIQPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQNSKVCSQGRQTWAQ--A
RGGHFHIPVGL------------------------LSWEA---------------PGLSH
SHSLPPAPPTGPA-----R--R--------------------------------------
-------------DLCHRAQR------A---------EGEL-------------------
-------------------------RPSDGEELVGGAEAVGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPVSTPCSSCRFPLR--DPSPSRPGWGGGAGS--QGARLGERGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPA------------RGDPGIQGLKGEKGESCSSC
SFAVAAQHLQPSAGAKGDMGPPGLGLPGLPVRPGYIPSPRFQA-------------W---
---AGVPQSCVLARQGEPCEPCRTLTEHQDEDSHVVALPGPRGEKGEPGPPGFGLPGKQV
SSGAC-G-GGIQGDAGNPGDPGTPGTTGRPGLSGEPGVRGPVGPKGEKG-DGCTACPGLQ
GALTDRAGLPGKP-GPKGDPGPEGVGRSG----YLPSRPSLPGLSFSPSCPLVLVGALAH
LCLLGPAWSTR---SSRTPRTEGHTG-VLCFHLQGLLGPRGPPGPAGEKGAKGS-----P
GVKGATGPMGPPGASVSGPPVRAPSVFHTGDVAETK-----AASPRS------PALGVDV
AYNLSPSFATPTPTQGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQVKRESEGRAGRQGA----------
----CCMLDPKCAAPWPQHLYSICRDCIQGKMAHEVALLESGEKGDQGIPGVPGLDSCAQ
CFMERERPRAEEAR---------------------------GDNHEGDPGCAGSPGLPG-
-PPGLPGQRGEEVRAWAGPR----------------------------GGWAVSSCQWSP
WTFWWLLVSPWEPPRTPHCTGFICPPGARGLRAVL---GPRPL--------------FLP
WPA---------------------------------------------------------
-------------ALSSPGLREERLREEDGAFITKFRACSC------------SWSLTTS
QGLGPPGPPGQPGPAGISAVVSAVL----------------LLASLPPRCLSLRVPIPL-
-----------------------PSLLGPEATPGSFPKFRQRLGIGGQSPSSSVSASGSG
PKGDRGATGERGLLGLPGQPGPPGHPGPPVRPHLSGLSPGGKG---------QWTLSGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMRFPMEMVAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGPPGRPGSP
GSPGLPGQIGREGRQGLPGMRG------EKGDIGVGIAGEIGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGPPGKTGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLSLWATFSHGANTGTQCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNTK-GPLILRLGAAPVSQPTRRVFPRGLPEEFALVLTLLLKKNTHQKTWYLFQV
TDANGYPQVSLEINSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLTVAGRVASV
HVDCSSASSQPLGPRRPTRPVGHVFLGLDAEQGKPVLFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELVEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRISQKAE
RGAKV------------DCPPCVHG---ARDSNVSEWRVC--------------------
-------------RVERARG----------------------------------------
-------------NDCVRISPDAPLQCAEGPKGEKGESGALVSVGPGIGQGWWGQKGEK-
GDGGIKGVPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPG-------------SSGIPGKEGPGGKPGKPGV---KGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPVPA------------RGDPGIQGIKGEKGEPCLSC
SSVAGVQHLVSSTGASGDVGSPGFGLPGLPVSDCFL-----------------PAQPS-S
GPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVLALPGPSGEKGEPGPPGFGLPGKQV
RWDIGRGLWRGDGDAGNPGDPGMPGTTGRPGLSGEPGVRGPVGPKGEKVSQPGTVLLPLQ
-------GEPG----------PPGRGVQGPQVNAPPRPG-------LLVQQ-------GQ
WGR-------LA-VASALSDLQGEPGAPGLPGIQVRL----PESSRRIAEEGGS-----P
GVKGATGPVGPPGASVSGPPGRDGQQGQTGPRGTPDGGG----------GD--ILGSLLP
PF---QGLH---ICLTSPGC----W---SGTQP--GLR----------------ETG--K
LQERWSPL--------------------TRVSSWLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEARG---------------------------DNSEGDPGCVGSPGLPG-
-PPGLPGQRGEEVRPGMRIHPQGSWGPGPPGFPGAVGSPGLPGIKGE-------------
----------------------------------RGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKV----SRT------------------------PGLP
HQHVEMPLSCFQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKVRAGDLCQAGYVCSPE------GLPPERPSQHQSLLGP-LV-PG--RL-GQGFSVYQ
LEGVRGPLAKAGA-------GGRGDCGKPGPP-GSTGRPGAEGPPGKQGFYGPPGPKGDP
GAA

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1802)

GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
G

ENSGT00900000140804_4_Linker_17_18 (1802, 1842)

DMVNYDEIKRFIIQQIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWV
SWTPGLWLLSLWVTFSHGARTGEQCPPSQQEGLKLEHSSDLSANVTGFNLIRRLNLMKTT
AIKKIRNPKGGPLILRLGTTPLTQPTRRVFPQGLPEEFALVLTLLLKKHTYRSTWYLFQV
TDGDGYPQISLEVNSQEQSLELRAQGQDGEFVSCIFPVPQLFDLHWHKLMLSVAGRVASV
HVDCISASSKPLGPRRPMRPVGHVFLGLDAEQGKPVAFDLQQAHIYCDPELVLEEGCCEI
LPGGCPSETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKADAKLMGRTSQKAE
RGAKVLQDSAT-----GECPPCVPG---AQDSNVTLGPSG---------------SKGEI
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------SDCVRISPDAPLQCSGGPKGEKGALGASGPPGLPGTEGQKGQKGEK-
GDGGIKGLPGRPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGIPGEAGGPPGPKGDKGSSGVPGKEGPGGKPGKPGVPGTKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPAKDILASAGQKGDRGDPGIQGIKGEKGEPCSSC
SLVTASQYLGPSSDS---------NLPDIL

PF01391 // ENSGT00900000140804_4_Domain_5 (751, 801)

GKAGAPGPRGLKGEKG--NFGEAGPTGG-L
GPPGPVGPTGTKGEKGEPCEPCAALSETQDGSSHVVHLPGQPGEKGEPGAPGFGLPGERG
KAGER-GLKGQKGEAGNPGDPGRPGTTGRPGLSGEPGVRGPIGPKGEKG-DACTACPTLQ
GAVTNMTSLPGKP-GPRGERGPEGVGRPG----KPGKPG-------LPGVQ----GPPG-
--LKGTQGEPGP-PGV

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GAQGPQGEPGAQGLPGGQGLPGPRGPPGPTGEKGAQGP-----P
GTKGATGLVGPPGASISGPPGE-----------------------KGSHGEKGDPGECSC
PSRGDPIFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGLPGIDGLPGQPGLTAEVGS----
-------LP-----IERQLLKSICGDCVQGQTTGPLSP---QEKGDQAISGVPGLDNCAR
CFLQRERPRAEEAR---------------------------GDNSEKDFDCIENPGLPG-
-SPGLPGQRGEEGPPGMRGSPGPPGPIG---------------LQGERGLRGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGPAGEKGEP-GPPGSEGLPGSP
GPVGPQGERGPQGKSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKTGAPGPPGPQAEKG----SEGIRGP--------------------TGLP
GPTGPPGPPGIQGPAGLDGLDGKDGKPGVRGDPGPPGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSNGRPGAEGEPGAMGPQGRPGPPGHIGP----PG--QPGPAGISAVG
MKGDRGTSGERGPAGIPGQPGPPGHPGPPGEP-GSDGATGKEGPPGKQGMYGLPGPKGDP
GPA

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1801)

GQKGQAGEKGRSGIPGGPGKSGSMGPIGPPGPAGERGHPGSPGPPGSPGLPGVPGSM

ENSGT00900000140804_4_Linker_17_18 (1801, 1842)

GDLVNYDEIKRFIRQEIIKMFDDRMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPAGQPGKAGHCNPSDCFGAMPMEDQYPPMKSMKGPFG

---------------------------------------------------------MWV
SWTPGLWLLSLWVT----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------FSHGFDLQQAYIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAKLMGRTSQKAE
KGT--------------KCPPCVHG---TQESNVSEGG-------------------AKT
GERGLPG-PAGPKGEKGARG----------------------------------------
-------------NDCVLISPDAPLQVRPR-------GEALDPSGCPGPPSILCPKGEKG
GYGGIKGLPGKPGRDGRP-GEICVIGPKGQKVSLESGGWRGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPG-------------SSGIPGKEGPGGKPGKPGVPGLKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPV------------RGDPGIQGIKGEKGEPCSPC
TLVAEAQYLGPSMGAQGEVGSSGSNLPGLLVSSPPLP-S----STP--PL----SLWYPE
GPPGQVGPAGSKGEKGEPCEPCSALSKPQDGDSHVVHLLGPAGEKGEPGPPGFGLPGKQG
KAGER-GLKGQKGEPGSPGDPGRPGTTGRPGLSGEPGVPGPLGPKGEKG-DACTACPSLQ
GAVTDMTGLPGKP-GPQGERGPEGVGRGL----P-SGPF-------LPGLYLLFLGPPVP
CGTLEHGPEPGPLPSNP------------------------APVTFVPYLPQGP-----P
GAEGATGPVGPPGASISGPPGE-----------------------KGSQGEKGDPGECSC
PSRGDPIFS---GMPVSGAENLLCWGRGLSSHLSSPP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGLPGIDGLPGQPGLTAEVGS----
-------LP-----IERQLLRSICGDCVQGQRTVALSSLEKGEKGDQAIPGVPGLDNCAR
CFSQRERPRAEEAR---------------------------GDNMEKDSDCAGSPGLPG-
-SPGLPGQRGEEGPPGMRGSPGPPGPIG---------------LQGDRGLQGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGPAGEKGEP-GPPGSEGLPGSP
GPVGPQGERGPQGKSGEKGDQVS--------DGPT-GLPGPTG-----------------
----SPGPPGIQVSVCPL-------------SVAGQ--------------------W--R
AEWELPPGPWHGGPAGLDGLDGKDGKP----DPGSPGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRQG------S-PGPPG--QPGPAGISAVG
LKGDRGASGERGPAGIPGQPGPPGHPGPPVRSHHLQHSLGERGLPGKQGLSGFPGPKGDP
GPT

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1802)

GQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
G

ENSGT00900000140804_4_Linker_17_18 (1802, 1842)

DMVNYDEIKRFIRQEIIKMFDDRMAYYTSRMQFPVEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKEGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGT
TGPMGQQGIPGIPGPPGPAGQPGKAGHCNPSDCFGAMPMEEQYPPMKNTKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPPILRLGAASVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRGPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAPLMGRISQKAE
RRAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFIGLPGKPGPKGEPGDPVSA------------RGDPGIQGIKGEKGESCLSC
SSIVGAQHLASSTGASEDVGSPGF

PF01391 // ENSGT00900000140804_4_Domain_5 (745, 799)

GLPGLPGRAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGSGLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTMTDVAGRPGQP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-LGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGASVSGPPGRDGQQGQTG---PRG-----TPGEKGPQGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNSEGDPGCV

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWT
SWVPGLWLLGLWATCSHAADTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPQGLPGEFALVLTLLLKKHTHQNTWYLFQV
TDAQGYPQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDAQLTGRVSQKTE
WGAKAHQEAAA-----NEXXXXVHG---AQESNXXXXXXX---------------XXXXX
XXXXXXXXX---------XX-------XXXXX------XXXXXXXXX--------XXXXX
XXXX---------XXXXXXXX---------------XXXXXXXXXXXXXXXXX

PF01391 // ENSGT00900000140804_4_Domain_1 (534, 604)

GQKGDR-
GDGGIKGSPGKPGRDGRP-GEICVMGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGL

ENSGT00900000140804_4_Linker_1_2 (604, 607)

PGI

PF01391 // ENSGT00900000140804_4_Domain_2 (607, 650)

GLPGTPG-PGGPPGRKGEKGNSGTPGKEGPSGKPGKPGMPGLKGEKXXXXXXXX
XXXXXXXSFIGLPGKPGPKEEPGDPAPA------------RGDPGIQGLKGEKGESCLSC
SSVGQSHTPGSITGAKGDV

PF01391 // ENSGT00900000140804_4_Domain_5 (740, 801)

GPPGFGLPGLPGKIGAPGPTGLKGEKG--NFGEAGPSGS-P
GPPGPVGPAGIKGEKGAPCE

ENSGT00900000140804_4_Linker_5_6 (801, 837)

PC--LSGPQEGSNHVQAFPGPPGEKGEPGPPGFGLP

PF01391 // ENSGT00900000140804_4_Domain_6 (837, 898)

GKQG
KAGDR-GLKGQKGDAGYPGDPGMPGTTGQPGLSGEPGVRGPMGPKGEKG-DGCTACS

ENSGT00900000140804_4_Linker_6_7 (898, 926)

SLQ
GAPTNMVGLPGKP-GPKGEPGPEGT

PF01391 // ENSGT00900000140804_4_Domain_7 (926, 975)

GQPG----KPGQPG-------LPGVQ----GPP--
-GLKGMQGEPGP-PGVGVQGSQGEPGAQGLPGTQGLPGPQGPPGRTGEKGAKGS-----P
GVKGAAGPMGPPGAGVSGSPGQDGQKGQAGVPGVRG-----MPGEKGSQGEKGEPGECSC
PSRGEPVFS---GMPGAPGL----W---M

PF01391 // ENSGT00900000140804_4_Domain_10 (1110, 1191)

GSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGLPGMQGMPGNNGLPGQPGA

ENSGT00900000140804_4_Linker_10_12 (1191, 1313)

AAELXXXX--
--------------XXXXXXXTICGDCGQSQTVQPAALLEKGEKGDQGIPGVPGFDNCAR
CFLERERPRAEEAR---------------------------GDNSEGEPGCA

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1374)

GSPGMPG-
-SPGLPGQRGEQGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGLTGEKGE-
----------LGPPGQPGYPGAMGPPGLPGIKGERGYVGPSGEKGES-GPPGSEGLPGPS
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----NEGMRGP--------------------SGLT
GSPGPPGPPGIQDL-CLDCLDGKC--KLLKGDPGPAGPPGLM---GPP-AQGKTGHPGLP
G-KGDCGQPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHAXXXXXXXXXXXXXXXXXXXXX
XXXXXXX---XXXXXXXXXXXXXXXXXXXGEP-GADGAAGKEGPPGKQGVYGPPGPRXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXRMAYYTSRMQFPVE

PF01391 // ENSGT00900000140804_4_Domain_18 (1838, 1896)

MAAAPGRPGPPGKDGTPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGV

ENSGT00900000140804_4_Linker_18_19 (1896, 1916)

GIAGENGLPGPPGPQGPPGY

PF01391 // ENSGT00900000140804_4_Domain_19 (1916, 1947)

GKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPVKNMKGPFG

---------------------------------------------------------MLA
SWAPGLWVLGLWATFSHGTNIGERCPTSQQEGLKLEHSSDPSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAAPLTQPTRQVFPRGLPEEFALVLTVLLKKNTFRNTWYLFQV
TDANGYPQISLEVNSQERSLELRARGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCDSASSQPLGPRQSIQPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKSRRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLMGRSIQKTE
RGTKVHQGTGV-----NECPPCVH---SARESNVTLGPSG---------------LKGGK
GERGLTG-PSGPKGEKGARG----------------------------------------
-------------NDCVRVSPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GLKGEKGESGDLGPSGLPGPTGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGR
PGPPGIGLPGTPGDPGGPPGPKGEKGSSGIPGKEGPGGKPGKPGVPGTKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPAWEGLGTVGLKGDRGDPGIQGMKGQKGEPCSSC
SSGVGAQHLGPSTGSSEDVGSPG

PF01391 // ENSGT00900000140804_4_Domain_5 (744, 801)

RGLPGLPGKSGIPGPRGLKGEKG--SFGDTGPAGV-P
GAPGPVGPAGIKGAKGEPCE

ENSGT00900000140804_4_Linker_5_6 (801, 834)

PCTALSTLQDGDTHVVRLPGPAGEKGEPGSPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGQPGLSGEPGIRGPAGPKGEKG-DGCTACPSLQ
GVLTDVSGLPGKP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ-------GP
PGPKGTQGEPGP-PGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGP-----P
GPSGAIGPMGPPGASVSGTPG-----------------------QKGSRGEKGEPGECSC
PSRGEPIFS---GMPGAPGL----W---MGSSSQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGS----
-------LP-----IEKHLLKSICGDCAQGQTAHPAFLLEKGEKGDQGIPGVPGFDNCAR
CFIERERPRAEEARG---------------------------DNSEGEPGCPGSPGLPG-
-PPGMPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSP

PF01391 // ENSGT00900000140804_4_Domain_12 (1360, 1429)

GLPGLQGERGLMGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGPAGEKGES-GPPGSEGLPGAQ
GPAGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHLGP-QGPPG--QPGPPGLSTVG
LKGDRGVPGERGLAGLPGQPGTPGHPGPPGEP-GSDGAAGKEGPPGKQGLYGPPGQKGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGNPGLPGLPGSM
GDMVNYDDIKRFIRQEIIKLFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGTPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGVGTAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKSMKGPFG

---------------------------------------------------------MWA
SWAPGLWLLSLWTTCSHGAYTGEQCPPSQQEGLKLEHSSDLSSNMTGFNLIHRLNLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPLRRVFPRGLPDEYALVLTLLLKKQTCRDTWYLFQV
TDGDGYPQISLEVNSQERSLELRARGQDGDFVSCIFPVPQLFDLRWHKLVLSVAGRVASV
HVDCTSAFSQPLGPRLPMKPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPEFTLEEGCCEI
SPGGCPPETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLSGRISQKAE
RGTKAHQEMAA-----DECPPCVYG---AQESNVTL

PF01391 // ENSGT00900000140804_4_Domain_0 (397, 494)

GPSG---------------PKGGK
GERGLPG-PSGPKGEKGAPG----------------------------------------
-------------

ENSGT00900000140804_4_Linker_0_1 (494, 510)

NDCVRISPDAPVQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 553)

GPKGEKGESGALGPSGLPGSIGQKGQKGEK-
GDGGIRGTPGKP

ENSGT00900000140804_4_Linker_1_2 (553, 617)

GLDXXXXX-XX---------XXXSQGQKGDPGFVGPEGLA-EPGPPGI
--GPGIGLPGTPGDPG

PF01391 // ENSGT00900000140804_4_Domain_2 (617, 658)

GPPGPKGDKGSSGVPGKEGPAGKPGKPGVPGLKGEKGDPCEVCP
TLPEGIQNFMGLPGKPGPKGEPGSPAPA------------RGEPGIQGIKGEKGESCLPC
NLGVEAQQLRPSTEATSNVGSPGFGLPGLPXXXXX---X

PF01391 // ENSGT00900000140804_4_Domain_5 (760, 801)

GLKGEKG--TFGDTGPAGS-P
GLPGPVGPAGTKGEKGEPCE

ENSGT00900000140804_4_Linker_5_6 (801, 838)

PCTVLSRTQDGDGHVVALPGPPGKKGEPGPPGLSLPG

PF07054 // ENSGT00900000140804_4_Domain_6 (838, 873)

KPG
KAGER-GMKGQKGDAGNPGDPGIPGTTGQPGL

ENSGT00900000140804_4_Linker_6_7 (873, 933)

SGDPGVRGPAGPKGQKG-DGCTACPSLQ
GAMVDMAGLPGKP-GPKGEPGSEGVGRPG---

PF01391 // ENSGT00900000140804_4_Domain_7 (933, 1006)

-KPGQPG-------LPGVQ----GPP--
-GLKGTQGEPGP-PGREVQGPRGLPGAQGLPGIQGLPGPQGPPGPTGEKGAKGP-----P
GVKGATGPAGPPGANVSGPPGRDGQQGQSGLPGARG-----MPGEKGSRGEKGEPGECSC
PSRGDPIFT---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------Q

PF01391 // ENSGT00900000140804_4_Domain_11 (1159, 1189)

GPPGVPGPPGPPGMPGLQGVPGINGLPGEPGLTAELGS----
-------LP-----IEQQLLKSICGDCAPGQTVRPVSILEK-EKGDQGIPGVPGLDNCAR
CFMERERPRAEEAR---------------------------GDNIEGDPDCVGSPGLPG-
-PPGLPGQRGEEXXXXXXXXXXXXXXXGPPGFPGAVGSPGLPXXXXXXXXXXXXXXXXX-
----------XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX

PF01391 // ENSGT00900000140804_4_Domain_13 (1429, 1518)

GPPGSDGIPGPQ
GPAGPRGERGPQGNSGQKGDQGF--------QGQP-GFPGLPG-----------------
----PPGLPGKPGAAGPPGPQAEKG----SEGMRGP--------------------PGLP
GSPGPPGPPGIQGPTGLDGLDGKDGKPGVRGEPGPAGTPGLM---GPPGFKGKTGHPGLP
GHKGDCGKPGPPGISGRPGAEGEPGAMGPQGRPGPPGHLGP-PGPPG--QPGPAGISALG
LKGDRGATGERGLAGIPGQPGPPGHPGPPGEP-GSDGEPGKEGPPGKQGLYGPPGPKXXX
XXXXXXXXXXXXGRAGLPGGPGKSGSMGPVGPPGPAGERGHPGSL-PAGSPGLPGLPGSM
GDMVNYDEIKRFIRQEIIKMFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPQGPPGY

PF01391 // ENSGT00900000140804_4_Domain_19 (1916, 1947)

GKMGP
TGPMGQQGIPGIPGPPGPIGQPGKTGHCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWA
SWAPGLWLLSLYVTYSHGADAGEQCPPSQQEGLKLEHRSDLSTNVTGFNLIHRLSLMKTS
AVKKIRNPK-GPFILRLGAVSVTQPTRRVFPRGLPSEFALVLTLLMKKHTHRNTWYLFQV
TDGDGYPQISLEVNSQEQSLELRTRGQDGDFVSCIFSVPQLFDLRWHKLVLSVAERVASV
HVDCMSASSQPLGPRRSIEPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPEFVLEEGCCEI
LPGGCPPETSKARRDTQNNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLSGRISQKPE
RGAKAHQETAA-----DECPPCVHG---AQESNVTIGPSG---------------PQGGK
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GLKGEKGESGALGPSGLPGSTGQKGQKGEK-
GDGGVKGSPGKPGRDGRP-GEVCVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGNSGVPGKEGPGGKPGKPGVPGLKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPA------------RGDPGIQGLKGEKGESCSSC
SFAVAAQHLQPSAGAK

PF01391 // ENSGT00900000140804_4_Domain_5 (737, 797)

GDVGPPGLGLPGLPGKAGAPGPTGLKGEKG--NFGEVGPAGN-P
GPPGPAGPTGIKGEKG

ENSGT00900000140804_4_Linker_5_6 (797, 823)

EPCEPCRALTEHQDEDSHVVALPGPR

PF01391 // ENSGT00900000140804_4_Domain_6 (823, 880)

GEKGEPGPPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGITGRPGLSGEPGVR

ENSGT00900000140804_4_Linker_6_7 (880, 908)

GPVGPKGEKG-DGCTACPSTQ
GALTDRA

PF01391 // ENSGT00900000140804_4_Domain_7 (908, 975)

GPPGKP-GPKGDPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGIQGEPGP-PGVGVQGPQGEPGAQGLPGIQGLPGPRGPPGPAGEKGAKGS-----P
GVKGAAGPVGPPGASVSGPPGPDGQQGQAGLPGARG-----MPGEKGSQGEKGEPGECSC
PSRGDLIFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1190)

GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPG

ENSGT00900000140804_4_Linker_10_12 (1190, 1306)

LTAELGS----
-------LP-----IEQHLLKSICGDCIQGKMAHEVALMESGEKGDQGIPGVPGLDSCTQ
CFMERERPRAEEAR---------------------------GDNH

PF01391 // ENSGT00900000140804_4_Domain_12 (1306, 1363)

EGDPGCAGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGRRGQKGPPGFPGAVGSPGLPGLQGERGLRGLTGEKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGSPGEKGES-GPPGSEGLPGPP
GPAGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQADKG----SEGIRGP--------------------SGLP
GPPGPPGSPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKPGHPGLP
GQKGDCGKPGPQGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
PKGDRGATGERGLLGLPGQPGPPGHPGPPGEP-GMDGAAGKEGPPGKQGLYGPPGPKGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPAGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGPPGRPGSP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1898)

GVGI

PF01391 // ENSGT00900000140804_4_Domain_19 (1898, 1946)

AGEIGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPIGPPGKTGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MLV
SWAPGLWVLGLWATFSHGTNIGERCPTSQEEGLKLEHSSDPSTNMTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAAPLTQATRRVFPRGLPEEFALVLTVLLKKHTFRNTWYLFQV
TDANGYPQVSLEVNSQERTLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVASRVASV
HVDCVSASSQPLGPRQPIRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKSRRDTQSNELIEINPQTEGKVYTRCFCLEEPHNSKVDAQLMGRSSQKAE
RGTKAHQETGA-----SECPPCAR---SARESNVTLGPPG---------------LKGGK
GDQGLTG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDGPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGDLGPSGLPGPTGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGAKGSSGIPGKEGPGGKPGKPGVPGTKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPA------------RGDPGIQGMKGEKGEPCSSC
SSGVGAQHLGPSTGVNEDMGSPV

PF01391 // ENSGT00900000140804_4_Domain_5 (744, 801)

HGLPGLPGKPGIPGPRGMKGEKG--SFGDAGPAGV-A
GPPGPVGPAGIKGAKGEPCEPCASLSKLQDGDTQVVHLPGPAGEKGEPGPPGSGLPGKQG
RAGER-GLKGQKGDAGNPGDPGTPGITGQPGMSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GALTDVSGLPGKP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ-------GP
PGLKGTQGEPGP-PGTGAEGPQGEPGTPGLPGIQGPPGPRGPPGSTGEHGAQGP-----P
GPKGATGPMGPPGASISGPPGHEGLRGQTGLQEHHRVQCPGSRGQKGSRGEKGEPGECSC
PSRGEPIFS---GMPGAPGL----W---MGSSSQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCAQGQAAHSASLLVKGEKGDQGVPGVPGFNDCAR
CFIERERPRAEEARG---------------------------DNSEGEPGCPGSPGLPG-
-PPGMPGQRGEEGPPGMRGSPGLPGPVGPPGFPGAVGSP

PF01391 // ENSGT00900000140804_4_Domain_12 (1360, 1430)

GLPGLQGERGPTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGPAGEKGES-GPPGSEGLPGPQ
GPAGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGMRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHLGP-QGPPG--QPGPPGLSTMG
LKGDRGSPGERGLAGLPGQPGTPGHPGPPGEP-GSDGAAGKEGPPGKQGLYGPPGPKGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGNPGLPGLPGSM
GDMVNYDDIKRFIRQEIIKLFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGDKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPIKSMKGPFG

---------------------------------------------------------MCV
SWAPGVWLLGLWATFSHGATTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXQVFPRGLPDEFTLVLTLLLKKHTSRSTWYLFQV
TDGDGYPQISLEVSSPERSLEFRARGQDGDFVSCIFSVPQLFDLRWHKLALSVAGRVASV
HVDCTSTSSQPLGPRRPLRPTGHVFLGLDAEQGKPVSFDLQQVHIYCDPDLVLEEGCXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDAQLTGRIGQKTE
QGTKAQREAAA-----DEXXXXXXX---XXXXXVTLSSSG---------------PKGGK
GERGPQG-PSGPKGEKGARG----------------------------------------
-------------SDCIRVSPDAPLQCAEGPKGEKGQSGASGPPGLPGSTGQKGQK

PF01391 // ENSGT00900000140804_4_Domain_1 (537, 607)

GEK-
GDLGVKGVPGKPGRDVRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGL

ENSGT00900000140804_4_Linker_1_3 (607, 629)

GLPGTPGDPGGPPGPKGDKGSS

PF01391 // ENSGT00900000140804_4_Domain_3 (629, 688)

GVPGKEGPSGKPGKPGIPGLKGEKGDPCEVCP
TLPEGFQNFMGLPGKPGPKGEPGEPAPA------------GGDPGIQGLKGEKGEPCWAC
SSAVVDQNLGPSSGATEGVSSPGLSLGLPXXXXXXXXXXXXXXXXX--XXXXXXXXXX-X
----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF01391 // ENSGT00900000140804_4_Domain_6 (838, 898)

XXG
AAGER-GLKGQKGEAGNPGDPGTPGAVGQPGLSGEPGGRGPAGPKGEKG-ESCTACTSLH
EALTETTSLLGLG-XXXXXXXXXXXXXXX----XXXXXXXXXXX--XXXXXXXXXXXXX-
-XXXXXXXXXXX--XXXXXXXX--XXXX-------------XXXXXXXXXXXXXXXXXXX
XXXXXXXXX-----XXXXXX-X----XXXXXXXXXX-----XXXXXXXXXXXXXXXXXXX
XXXXXXXXX---XXXXXXXXXXXXXXXXXGSSWQPP------------------------
------------------QGPGVP

PF01391 // ENSGT00900000140804_4_Domain_11 (1165, 1189)

GPPGPPGMPGLQGMPGNNGLPGQPGLTAELGS----
-------LP-----IEQQLLKSICGDCAQGQLASPVS-REKGEKGDQGIPGVPGLDSCAR
CFLERERPTAEQAQ----------------------------RDVSEDPGCAGSPGLPG-
-PPGLPGQRGGEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGLQGERGLRGLTGDKGE-
----------PXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXGPPGSE-GP

PF01391 // ENSGT00900000140804_4_Domain_13 (1438, 1531)

GAP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKX----XXXXXXX--------------------XXXX
XXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXGFKGKTGHPGLP
GPKGDCGNPGPPGGSGRPGAEXXXXXXXXXXXXXXXXXXGP-PGPPG--QPGPAGISAVX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXGEP-GADGMAGKEGPPGKQGLYGPPGPKGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPAGPPGPAGERGHPGSPGPTGSPGLPGLPGSM
GDMVNYDEIKRFIRQEVIKMFDDRMAYYTSRVQFPMEMVA

PF01391 // ENSGT00900000140804_4_Domain_18 (1841, 1887)

APGRPGPPGKEGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGXPGT

ENSGT00900000140804_4_Linker_18_19 (1887, 1916)

K-EKGDIGVGIAGENGLPGPPGPQGPPGY

PF01391 // ENSGT00900000140804_4_Domain_19 (1916, 1947)

GKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGALPVEQQYPP---------

---------------------------------------------------------MRA
PWVPGLWLLSLWAVCSRGADTGEQCPPSQQEGLKLEHRSHLSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAAALTQPVRRVFPRGLPDEFALVLTLLLKKHTHQSTWYLFQV
TDGDGYPQISLEVNSPERSLELRARGQDGDFVSCIFRVPQLFDLRWHKLVLSMSERVASV
HVDCISASSKPLGPRQPMRPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGRVYTRCFCLEEPQNSKVDAQRTGSISQQAE
RGTKARQETAA-----DECPPCVHG---ARGSNVTVSPSG---------------PKGGK
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 561)

GPKGEKGESGALGPSGLPGSTGQKGQKGEK-
GDGGIKGSPGKPGRDGRP-GEICVMGPKGQ---------KGDPGFVGPEGLAGEPGRPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGVPGKEGPGGKPGKPGVPGLKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPAPAKEGLGAVGWKGDRGDPGIQGPKGEKGDSCLSC
SLAVGSQHLGPSTGAK

PF01391 // ENSGT00900000140804_4_Domain_5 (737, 797)

GDTGAPGFGLPGLPGKVGAPGPAGLKGEKG--NFGETGPAGR-Q
GPPGPVGATGIKGEKG

ENSGT00900000140804_4_Linker_5_6 (797, 823)

EPCEPCPALSRPQDGDSYTVALPGPP

PF01391 // ENSGT00900000140804_4_Domain_6 (823, 881)

GEKGETGPPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGVPGTTGQPGLSGEPGVRG

ENSGT00900000140804_4_Linker_6_7 (881, 908)

PMGPKGEKG-DGCTACPSLQ
GAVTNMA

PF01391 // ENSGT00900000140804_4_Domain_7 (908, 976)

GLPGKP-GPKGEPGPEGMGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGIQGEPGL-PGKGVQGPQGEPGVQGLPGIQGLPGPRGPPGPAGEKGAKGS-----P
GLKGAAGPMGPPGASISGPPGPDGQQGQTGLPGARG-----MPGEKGPQGEKGEPGECSC
PSRGDPIFS---

PF01391 // ENSGT00900000140804_4_Domain_10 (1093, 1190)

GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGNTGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQTARPVAFLEKGEKGDQGVPGVPGLDSCAR
CFAERERPRAEEAR---------------------------GDNGEGDLDCAGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGPTGEKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYVGPAGEKGES-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGA--------------------PGMP
GPTGPPGPPGIQGPAGLDGLDGKDGKPGLR

PF01391 // ENSGT00900000140804_4_Domain_14 (1591, 1650)

GDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHIGP-PGPPG--QPGPAGISAMG
LKGDRGATGERGLLGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGPKGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGSPGLPGMPGSM
GDMVNYDEIKRFIRQEILKMFDERMAYYTSRMQFPMEMAAV

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGVPGMRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1898)

GIGI

PF01391 // ENSGT00900000140804_4_Domain_19 (1898, 1946)

AGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------CPPCAY---GAQRSNVTLGPSE---------------PQGGK
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISQDAPLQCAEGPKGEKGEAGGVGPSGLPGSIGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGEPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVPGTKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPASAREGLGTVGLKGDRGDPGIQGLKGEKGEPCLSC
STAVGAQHLGPSP---------GL

PF01391 // ENSGT00900000140804_4_Domain_5 (745, 801)

GLPGLPGKAGVPGPRGLKGEKG--NFGEPGPAGS-P
GPPGQVGPAGIKGAKGEPCE

ENSGT00900000140804_4_Linker_5_6 (801, 837)

PCSALSRTQDGDSHVVHLPGPVGEKGEPGPPGFGLP

PF01391 // ENSGT00900000140804_4_Domain_6 (837, 891)

GKQG
KAGER-GLKGQKGDAGSPGDPGTPGTTGQPGLSGEPGIRGPMGPKGEKG-DGCTACPNLQ
GALTDMAGLPGKP-GPKGEQGPEGVGRPG----KPGQPG-------LPGVQ-------GP
PGLKGTQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1033)

GVQGPQGEPGVQGLPGVQGPPGPQGPPGRTGEKGVQGP-----P
GMKGATGPMGPTGASVSGPPG-----------------------EKGSRGEKGEPGECSC
PSRGDPIFS---GMPGAPGL----W---MGSSSQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLIKSICGDCAQGQMAQPASVLVKGEKGDQGIPGVPGLDNCAR
CFLERERPRAEEARG---------------------------DNG

PF01391 // ENSGT00900000140804_4_Domain_12 (1306, 1363)

EGDPGCPGSPGLPG-
-PPGVPGQRGEEGPPGMRGSPGLPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGPAGEKGEL-GPPGSEGLPGPA
GPAGPRGERGPQGAAGEKGDQGF--------QGQP-GFPGLPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPTGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-AGPPG--QPGPAGISALG
LKGDRGAPGERGLAGLPGQPGTPGHPGPPGEP-GTDGAAGKEGPPGKQGLYGPPGPKGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGMPGSM
GDMVNYDEIKRYIRQEIIKMFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPTGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGANCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNHQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRINQKAE
RGAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVSARDHPKAVGQKGDRGDPGIQGIKGEKGESCLSC
SSVVGAQHLASST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGRAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 820)

EPCPALSNLQDGDVRVVALP

PF01391 // ENSGT00900000140804_4_Domain_6 (820, 871)

GPSGEKGEPGPPGFGLLGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPVGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGRGVQGPQGEPGAPGLPGIQVRLPESW-RRIAGERSILGYGLTNCA
SICRDFRDLGDHLAPLERRVPRD------------------LQG----------------
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--------------------------------IRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGTEGEPGAMGPQGRPGPPGHLGP-QGPPG--QPGPPGISTMG
LKGDRGAPGERGLAGLPGQPGTPGHPGPPG-------------PPGKQGLYGPPGPKGDP
GPA

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1801)

GQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGNPGLPGLPGSM

ENSGT00900000140804_4_Linker_17_18 (1801, 1842)

GDMVNYDDIKRFIRQEIIKMFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDI

ENSGT00900000140804_4_Linker_18_19 (1894, 1897)

GVG

PF01391 // ENSGT00900000140804_4_Domain_19 (1897, 1946)

IAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFGHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIHRLSLMKMS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRISQKAE
RGAKV------------ECPPCVHG---AWDSNVSEW-------------------RGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQVRL---------GGDGPSGLPGSTGEKGQKGEK-
GDGGIKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGMGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPVPA------------RGDPGIQGIKGEKGEPCLSC
SSVVGAQHLVSST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGRAGVP---GLKGEKG--NFGEAGPAGS-P
GTPGPVGPAGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 820)

EPCPALSNLQDGDVRVVALP

PF01391 // ENSGT00900000140804_4_Domain_6 (820, 881)

GPSGEKGEPGPPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGP------RG-DGCTACPSLQ
GTVTDMAGRPGQP-GPKGEQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQV---------CVSLGGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGLPGASVSGPPGRDGQQGQTGLR---G-----TPVSTVLLYFQGEPGECSC
PSRGDLIFS---GMPGPP------------------------------------------
---------------------GIPGPPGPPGVPGLQVKGE-KRMRSLGGRAHGSGWLLLA
GPQGCCSPTPK---TQTCHFSLLCLPASQGGKEGPLSL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------

---------------------------------------------------------MWA
CWAPGLWLLGLWATCSHGANTGEMTHPQPFSGVACTHLPTLGVSPEGFNLIRRLNFMKTS
AIKKIRNPN-GPLILRLGATPLTQPTRRVFPRGLPDEFTLVLTLLLKKHTHQNTWYLFQV
TDGEGYPQISLEVNSQEQSLELRALGHDGDFVSCIFSVPQLFDLRWHKLQLSVAERVASV
HVDCTSASSQPLGPRRPIRPVGHVFLGLDSEQAKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPEASKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQSSKVDAQLTGRISQKAD
RGTKAHQETAP-----DECPPCVHG---AQESNVSEFWSH---------------PQGGK
GEQGPPG-PSGLKGEKGARG----------------------------------------
-------------NDCVRVSPDAPLQCSEGPKGEKGESGALGPSGPPGSTGQKGQK

PF01391 // ENSGT00900000140804_4_Domain_1 (537, 607)

GEK-
GDGGIKGSMGKPGRDGRP-GEICVMGPKGQ---------KGDPGFVGPEGLAGEPGPPGR
PGPPGI

ENSGT00900000140804_4_Linker_1_2 (607, 617)

GLPGIPGDPG

PF01391 // ENSGT00900000140804_4_Domain_2 (617, 658)

GPAGPKGDKGSSGVPGKEGPGGKPGKPGVPGLKGEKGDPCEVCP
TLPEGFQNIVGLPGKPGPKGEPGDPAPA------------RGDPGIQGLKGEKGESCLSC
SPAVGAQQLGPLAGIKGDVGPPGLGFPGLPGKVGAPGPAGLKGEKV--RPGLEVRDTWIP
SLA-WGPQPCVLARQGEPCEPCSALSEPQNGNSRVAALPGPPGEKGEPGPPGFGLP

PF01391 // ENSGT00900000140804_4_Domain_6 (837, 898)

GKQG
KAGER-GLKGQKGDAGNPGDPGTPGTSGQPGLSGEPGVRGPMGPKGEKG-DGCTACP

ENSGT00900000140804_4_Linker_6_7 (898, 926)

SLQ
GALTQAAGLPGKP-GPKGEPGPEGV

PF01391 // ENSGT00900000140804_4_Domain_7 (926, 975)

GWPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGMGVQGPEGEPGAPGLPGVQGFPGPRGPPGPAGEKGPKGS-----P
GVKGAIGPMGLPGASVSGPPGRDGQQGQTGLPGARG-----TPVSSVWRQQEGEPGECSC
PSRGDPVFS---GMPGAPGL----W---MGSSWQ

PF01391 // ENSGT00900000140804_4_Domain_10 (1115, 1188)

PGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGIPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLQSICGDCVQGQKARPAALLQKGEKGDQGIPGVPGFDNCAR
CFTERERPRAEEAR---------------------------GDNSEGDPGCAGSPGLPG-
-PPGLPGQRGEEGPPGVRGSPGPPGPVGPPGFPGAVGSPGLPGLQGERGLRGLTGEKGE-
----------LGPPGQPGYPGAMGPPGLPGIKGERGYAGPAGEKGES-GPPGSEGLPGPP
GPAGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGMRGP--------------------SGMP
GPPGPPGPPGIQGPAGLDGLDGKDGKPGFRGEPGPAGPPGLM---GPPGFKGKTGHP

PF01391 // ENSGT00900000140804_4_Domain_14 (1618, 1680)

GLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHAGP-PGPPG--QPGPAGISAVG
QKGDQGATGERGLAGFPGEPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGPKGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPVGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRIQFPME

PF01391 // ENSGT00900000140804_4_Domain_18 (1838, 1896)

VAAAPGRPGPPGKDGAPGRPGSP
GAPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGV

ENSGT00900000140804_4_Linker_18_19 (1896, 1916)

GIAGENGLPGPPGPQGPPGY

PF01391 // ENSGT00900000140804_4_Domain_19 (1916, 1947)

GKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKSMKGPFG

---------------------------------------------------------MWA
SWASGLWLLGLWATCSHGANTGEHCP-SQQEGLKLEHRSDLSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAAPLTQPTRRVFPRGLPNEFALVLTLLLKKRTHQNMWYLFQV
TDEDGYPQISLEVNSQEQSLELRARGQDGDFVSCIFSVPQLFDLHWHKLQLSVAERVASV
HVDCTSASSQPLGPRRPMQPVGHVFLGLDAEQGKPVPFDLQQAHIYCDPELVLEEGCCEI
LPGGCSPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLTGRINQKTE
KGTKAHQETAS-----DECPPCVHG---ARESNVTI

PF01391 // ENSGT00900000140804_4_Domain_0 (397, 494)

GPSG---------------LKGGK
GEQGLPG-PSGPKGEKGARG----------------------------------------
-------------

ENSGT00900000140804_4_Linker_0_1 (494, 510)

NDCVQISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 580)

GPKGEKGESGALGPSGLPGSTGQKGQKGER-
GDGGIKGSMGKPGRDGRP-GEICIIGPKGQ---------KGDPGFVGPEGLAGEPGPPGQ
PGPPGIGLPGTPGDPGGPPGPKGNKGSSGTPGKEGPGGKPGKPGV-------GDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGNPAPA------------RGDPGIQGLKGEKGESCLSC
SSAVAAQHLGPFTGAK

PF01391 // ENSGT00900000140804_4_Domain_5 (737, 798)

GDVGPPGFGLPGLPGKVGDPGPTGLKGEKG--DFGEAGPAGS-S
GPPGPVGPTGIKGEKGE

ENSGT00900000140804_4_Linker_5_6 (798, 837)

PCEPCPALSKPQDGDSQVVALPGPPGEKGEPGPPGFSLP

PF01391 // ENSGT00900000140804_4_Domain_6 (837, 898)

GKQG
KAGER-GLKGQKGDAGNPGDPGIPGTSGQPGLSGEPGVRGPVGPKGEKG-DGCTACP

ENSGT00900000140804_4_Linker_6_7 (898, 933)

SLQ
GTLTDMAGLPGKP-GPKGDPGPEGVGRPG---

PF01391 // ENSGT00900000140804_4_Domain_7 (933, 1006)

-KPGQPG-------FPGVQ----GPPG-
--LKGVQGEPGP-PGMRVQGPQGEPGAQGLPGIQGLPGPRGPPGPAGAKGTKGS-----P
GVKGAIGPVGPPGASVSGPPGADGRQGQTGLPGARG-----MPGEKGSQGEKGEPGECSC
PSRGDPVFS---GMPGAPGL----W---MGSSWQ

PF01391 // ENSGT00900000140804_4_Domain_10 (1115, 1188)

PGP-----------------------
-----------------QGPPGIPGPPGPPGMPGLQGEPGNNGLPGQ

ENSGT00900000140804_4_Linker_10_12 (1188, 1307)

PGLTAELGS----
-------LP-----IEQHLLQSLCGDCVQGQRAHPAAFLQKGEKGDQGIPGVPGLDSCAR
CFAERERPRAEEAR---------------------------GDNNE

PF01391 // ENSGT00900000140804_4_Domain_12 (1307, 1368)

GEPGCAGSPGLPG-
-PPGQPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGL-GLTGEKGE-
----------LGPPGQPGYPGAMGPPGLPGIKGERGYTGPSGEKGES-GPPGSEGLPGPA
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKEGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GPPGPPGPPGIQGPAGLDGLDGKDGKPGLPGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-QGPPG--QPGPAGISAVG
LKGDRGATGERGLSGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGLYGPPGPKGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPVGAPGPAGERGHPGSPGPVGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRIQFPVE

PF01391 // ENSGT00900000140804_4_Domain_18 (1838, 1896)

VAAAPGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGI

ENSGT00900000140804_4_Linker_18_19 (1896, 1916)

GIAGDNGLPGPPGPQGPPGY

PF01391 // ENSGT00900000140804_4_Domain_19 (1916, 1947)

GKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWA
SWAPGLWLLSLCVICSHEADTGERCPPSQQEGLKLEPRSDLSTNVTGFNLIRRLRLMKIS
AVKKIRNPK-GPLILRLGAVSVTQPVRRVFPRGLPSEFALVLTLLLKKHTHQNTWYLFQV
TDGNGYPQISLEVNSQERSL-FRARGQDGDFVSCIFSVPQLFDLRWHKLVLSVAERVASV
HVDCTSVSSRPLGPWRPMQPVGHVFLGLDAEQGKPVSFDLQQAHIYCDSDLVLEEGCCEI
LPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLTGRISQEAE
RETKVHQETAV-----DECPPCVHX---XXXXXVTIGPSG---------------PQREK
GEQGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 580)

GRKGEKGESGALGPSGLPGSTGQKGQKGDK-
GDGGIKGSPGKPGRDGRP-GEICVMGPKGQ---------

ENSGT00900000140804_4_Linker_1_2 (580, 617)

KGDPGFVGPEGLAGEPGPPGL
PGPAGIGLPGTPGDPG

PF01391 // ENSGT00900000140804_4_Domain_2 (617, 658)

GPPGPKGDKGSSGVPGKEGPGGKPGKPGVPGLKGEKGDPCEVCP
ALPEGFQNFVGLPGKPGPKGEPGVPAPA------------RGDPGIQGLKGEKGESCLSC
SSPVAAQHLGPSIGPK

PF01391 // ENSGT00900000140804_4_Domain_5 (737, 798)

GDVGPPGLGLPGLPGKVGAPGPTGLKGEKG--NFGEAGPAGG-L
GPPGPVGPTGVKGEKGE

ENSGT00900000140804_4_Linker_5_6 (798, 838)

PCESCSALXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF01391 // ENSGT00900000140804_4_Domain_6 (838, 898)

XXG
KAGEH-GLKGQKGDAGNPGDPGTPGTMGRPGLSGEPGVRGPSGPKGEKG-DGCTACP

ENSGT00900000140804_4_Linker_6_7 (898, 933)

SLQ
GALTDRAGPPGKP-GLKGDPGPEGVGRPG---

PF01391 // ENSGT00900000140804_4_Domain_7 (933, 1006)

-KPGQPG-------LPGVQ----GPPG-
--LKGIQGEPXXXXXVGVQGPQGEPGAQGLPGIQGLLGPRGPPGPAGEKGAKGS-----P
GVKGATGPVGPAGASVSGPPGPAGQQGQTGLPGARG-----MLGEKGTQGEKGEPGECSC
PSRGDPIFS---GMPGAPGL----W---MGSSWQP

PF01391 // ENSGT00900000140804_4_Domain_10 (1116, 1189)

GP-----------------------
-----------------QGPPGVPGPPGPPGTPGLQGVPGSNGLPGQPGLTAELGS----
-------LP-----IEQHVLKSICGDCVQGQTAHPAALLESGEKGDQGNPGVPGLDSCAR
CFTERERPRAEEAR---------------------------GDNGEGDAGCAGSPGLPG-
-APGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGLTGEKGE-
----------P

PF01391 // ENSGT00900000140804_4_Domain_12 (1392, 1452)

GPPGQPGYPGAMGPPGLPGIKGERGYGGSPGEKGES-GPPGSEGLPGPP
GPAGPRGERGPQGNLGEKGDQXX--------XXXX-XXXXXXG-----------------
----PPGFPGKAGAPGLPGPQAEKG----SEGIRGP--------------------SGLP
GPPGPPGSPGIQXXXXXXXXXXXXXXXXXXGDPGPAGPPGLM---GPPGFKGKPGHPGLP
GLKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHVGP-PG-SG--QPGPAGISAVG
PKGDRGSTGERGLSGLPGQPGPPGHPGPPGEP-GADGEAGKEGPPGKQGMYGPPGPKGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPSGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPME

PF01391 // ENSGT00900000140804_4_Domain_18 (1838, 1896)

MAAAPGRPGPPGKDGPPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGV

ENSGT00900000140804_4_Linker_18_19 (1896, 1916)

GIAGEVGLPGPPGPQGPPGY

PF01391 // ENSGT00900000140804_4_Domain_19 (1916, 1947)

GKMGA
TGPMGQQGIPGIPGAPGSMGPPGKAGHCNPSDCFGAMPMEQEYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAHCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKMS
AIKKIRNPK-GPLILRLGAASVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDADGYPQISLEVNNQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRINQKAE
RGAKVHRETAA-----DECPPCVHG---AQDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGQSGALGPSGLPGSTGEKGQKGEK-
GDGGLKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGDPVSA------------RGDPGIQGIKGEKGESCLSC
SSVVGAQHLASST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGKAGLP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPVGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDVAGRPGQP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGMQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGTSVSGPPGRDGQQGQTG---PRG-----TPGEKGPRGEKGEPGECSC
PSRGDLVFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVLGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNN

PF01391 // ENSGT00900000140804_4_Domain_12 (1306, 1363)

EGDPGCIGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGLYGPPGPKGDP
GATGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCSPSDCFGAMPMEQQYPPMKTMKGPFG

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------CPPCVHG---TQESNVTLGPSG---------------SKGET
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAD

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 561)

GPKGEKGASGASGPSGLPGLTGQKGQKGEK-
GDGGIKGLPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGEAGGPPGPKGDKGSSGVPGKEGPGGKPGKPGVPGVKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDSAPARDGLGSAGQKGDQGDPGIQGIKGEKGEPCSSC
TLGAEAQYLGPSPG---------SSLPGLLEK

PF01391 // ENSGT00900000140804_4_Domain_5 (753, 800)

SGAPGPRGLKGEKG--NLGEAGPVGS-P
GPPGPVGPTGTKGEKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 835)

EPCSALSKPQDGDRHVVHLPGPTGEKGETGPPGFG

PF01391 // ENSGT00900000140804_4_Domain_6 (835, 891)

LPGKQG
KAGER-GLKGQKGEPGNPGDPGRPGTTGRPGLSGEPGVPGPLGPKGEKG-DACTACPSLQ
GAVTDMTGLPGKP-GPPGEQGPEGVGRPG----KPGKPG-------LPGVQ----GPPG-
--LKGSQGEPGP-PGV

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1033)

GAQGPQGEPGTQGLPGIQGFPGPQGPPGPTGEKGAQGP-----P
GAKG---PVGPPGVGISGPPGE-----------------------KGSQGEKGEPGECSC
PSRGDSIFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGLPGIDGVPGQPGLAAEVGS----
-------LP-----IERQLLKSICGDCVQGQRTIALSPLEKGEKGDQAIPGVPGLDNCAR
CFSQRERPRAEEAR---------------------------GDNMEKDSDCAGSPGLPG-
-SPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGDRGLQ

PF01391 // ENSGT00900000140804_4_Domain_12 (1372, 1430)

GLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGPAGEKGEP-GPPGSEGLPGSP
GPVGPQGERGPQGKSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKTGAPGPPGPQAEKG----SEGIRGP--------------------TGLP
GSTGPPGPPGIQGPAGLDGLDGKDGKPGVRGDPGPPGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRQGPPGHIGP-PGPPG--QPGPAGISAVG
LKGDRGTSGERGPAGIPGQPGPPGHPGPPGEP-GTDGATGKEGPPGKQGLHGIPGPKGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPVGPPGPVGERGHPGSPGPAGSPGLPGVPGSM
GDLVNYDEIKRFIRQEIIKMFDDRMAYYTSRMQFPVEMVAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKEGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPSGQPGKAGHCNPSDCFGAMPMEEQYPPMKNTKGPFG

------------------------------------------------------------
-------MLGLWTTFSHGTNIGEQCPTSQQEGLKLEHSSDPSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAAPLTQPTRRVFPRGLPEEFALVLTVLLKKHTFRNTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCVSASSQPLGPRQSIRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LTGGCPLETSKSRRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLMGRSIQKAE
RGTKVHQGTEV-----NECPPCAH---SARESNVTLGPSG---------------LKGGK
GERGLTG-PSGPKGEKGARG----------------------------------------
-------------NDCVRVSPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGDLGPPGLPGPTGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGEKGSSGIPGKEGPGGKPGKPGVPGTKGEKGDPCEVCP
TLPEGSQNFVGLPGKPGPKGEPGDPAPAWEGQGTVGLKGDRGDPGIQGMKGEKGEPCSSC
SPGVGAQHLGPS---------PG

PF01391 // ENSGT00900000140804_4_Domain_5 (744, 801)

HGLPGLPGTSGIPGPRGLKGEKG--SFGDTGPAGV-P
GSPGPMGPAGIKGAKGEPCEPCTALSGLQDGDIRVVHLPGPAGEKGEPGSPGFGLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKG-DGCTACPSLQ
GALTDVSGLPGKP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ-------GP
PGPKGTQGEPGP-PGT

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1033)

GAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGP-----P
GPNGAIGPMGPPGAGVSGPPG-----------------------QKGSRGEKGEPGECSC
PSRGEPIFS---GMPGAPGL----W---MGSSSQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGS----
-------LP-----IEKHLLKSICGDCAQGQTAHPAFLLEKGEKGDQGIPGVPGFDNCAR
CFIERERPRAEEARG---------------------------DNSEGEPGCSGSPGLPG-
-PPGMPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGPSGEKGES-GPPGSEGLPGPQ
GPAGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHLGP-QGPPG--QPGPPGLSTVG
LKGDRGVPGERGLAGLPGQPGTPGHPGPPGEP-GSDGAAGKEGPPGKQGLYGPPGPKGDP
GPA

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1801)

GQKGQAGEKGRSGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGNPGLPGLPGSM

ENSGT00900000140804_4_Linker_17_18 (1801, 1842)

GDMVNYDDIKRFIRQEIIKLFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKSMKGPFG

---------------------------------------------------------MLA
SWAPGLWLLGLWATCSHGAYTGEQCPPSQQEGLKLEHSSDLSSNVTGFNLIRRLNLMKMS
AIKKIRNPK-GPLILRLGAAPLTQPLWRVFPQGLPDEFALVLTLLLKKHTHQNTWYLFQV
TDGDGYPQISLEVNSQEQSLELRARGQDGDFVSCIFPVPQLFDLSWHKLVLSVAGRVASV
HVDCTSASSQPLGPRQPVQPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELALEEGCCEV
SPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLSGRISQKAE
RGTKAQQETAA-----GECPPCAHS---AQESNVTF

PF01391 // ENSGT00900000140804_4_Domain_0 (397, 494)

GSSG---------------PKGGK
GERGLPG-PSGPKGEKGARG----------------------------------------
-------------

ENSGT00900000140804_4_Linker_0_1 (494, 510)

NDCVQISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 580)

GPKGEKGESGALGPSGLPGSTGQKGQKGEK-
GDGGIKGMPGKPGRDGRP-GEICVIGPKGQ---------

ENSGT00900000140804_4_Linker_1_2 (580, 617)

KGDPGFVGPEGLAGEPGPPGL
PGPPGIGMPGTPGDPG

PF01391 // ENSGT00900000140804_4_Domain_2 (617, 658)

GLPGPKGDKGSSGVPGKEGPGGKPGKPGVPGLKGEKGDPCEVCP
TLPEGFQSFVGLPGKPGPKGEPGNPLPAREGLRTVGQKGDRGDPGIQGIKGEKGESCSSC
NLGVEAQQFRPSTGATGNV

PF01391 // ENSGT00900000140804_4_Domain_5 (740, 801)

DSPGFGLPGLLGKAGAPGPTGLKGEKG--TSGDAGPAGS-P
GLPGPVGPAGTKGEKGEPCE

ENSGT00900000140804_4_Linker_5_6 (801, 837)

PCTVLSKPQDGDGHVVALPGPPGKKGDPGPPGLNLP

PF01391 // ENSGT00900000140804_4_Domain_6 (837, 898)

GKPG
KAGER-GMKGQKGEAGNPGDPGIPGTTGQPGLSGEPGVRGPAGPKGEKG-DGCTACP

ENSGT00900000140804_4_Linker_6_7 (898, 926)

SLQ
GAMTNMAGLPGKP-GPKGEPGPEGV

PF01391 // ENSGT00900000140804_4_Domain_7 (926, 975)

GRPG----KPGQPG-------LPGVQ----GPRG-
--LKGTQGEPGP-PGMGIQGPQGEPGAQGLPGIQGLPGPQGPPGPTGEKGAKGP-----P
GVKGATGPVGPPGASVSGPPGE-----------------------KGSQGEKGEPGSAPA
PLRAQPTAS---HTAGAPGL----W---MGSSWQ

PF01391 // ENSGT00900000140804_4_Domain_10 (1115, 1188)

PGP-----------------------
-----------------QGPPGVPGPPGPPGVPGLQGVPGNNGLPGQ

ENSGT00900000140804_4_Linker_10_12 (1188, 1321)

PGLTAELGS----
-------LP-----IEQQLLKSICGECAQGQTARPASILEEGEKGDQGIPGVPGLDNCAR
CFIERERPRAEEAR---------------------------GDHNEGDPDCGGSPGLPG-

PF01391 // ENSGT00900000140804_4_Domain_12 (1321, 1406)

-APGLPGQRGEEGPPGMRGSPGLPGPIG---------------LQGERGLRGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGPAGEKGES-GPPGSEGIPGSQ
GPVGPRGERGPQGKSGEKGDQGF--------QGQP-GFPGLPG-----------------
----PPGSPGKAGAPGPPGPQAEKG----SEGIPGS--------------------SGIP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGVRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGSPGHLGP-PGPPG--QPGPAGISAMG
LKGDRGATGERGLAGIPGPPGPPGHPGPQGEP-GADGEAGKEGPPGKQGLYGPPGPKGDP
GPSGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPIE

PF01391 // ENSGT00900000140804_4_Domain_18 (1838, 1896)

MAAAPGRPGPPGKDGSPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGV

ENSGT00900000140804_4_Linker_18_19 (1896, 1916)

GIAGESGLPGPPGPQGPPGY

PF01391 // ENSGT00900000140804_4_Domain_19 (1916, 1947)

GKMGP
TGPMGQQGIPGIPGPPGPMGQPGKTGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFGHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIHRLSLMKMS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSQVDAQLTGRISQKAE
RGAKVHQETAA-----DECPPCVHG---AWDSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGARG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGIKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGMGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPG---VKGEKGDPCEVCP
TLPEGFQNFVGLPGKPGPKGEPGDPVPA------------RGDPGIQGIKGEKGEPCLSC
SSVVGAQHLVSST

PF01391 // ENSGT00900000140804_4_Domain_5 (734, 800)

GASGDVGSPGFGLPGLPGRAGVP---GLKGEKG--NFGEAGPAGS-P
GTPGPVGPAGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDMAGRPGQP-GPKGEQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS-----P
GVKGATGPVGPPGASVSGPPGRDGQQGQTG---LRG-----TPGEKGPRGEKGEPGECSC
PSRGDLIFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ
CFLSLERPRAEEAR---------------------------GDNSEGDPGCV

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPVGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGSPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGATGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GTDGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWA
SWAPGLWLLSICITCSHGAGTGEQCPPSQQEGLKLEHRSDLSTNVTGFNLIHRLSLMKTS
AIKKIRNPK-GPLILRLGATSVTQPTRRVFPRGLPGEFALVLTLLLKKHTHQNTWYLFQV
TDGDGYPQISLEVNSQERSLELRARGQDGDFVSCIFLVPQLFDLRWHKLVLSVAERVASV
HVDCTSASSQPLGPRRPIRPVGHVFLGLDAEQGKPVSFDLQQAHIYCDPEFVLEEGCCEI
SPGGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLTGGISQKAE
RGAKAHQDTAA-----DECPPCVHG---ARESNVTIGPSG---------------PKGGK
GEPGPPG-PLGPKGEKGARG----------------------------------------
-------------NDCVRISLDAPLRCSE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGQKGQKGEK-
GDGGIQGSPGKPGRDGRP-GEICVMGPKGQ---------KGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGVPGKEGPGGKPGKPGVPGLKGQKGDPCEVCP
TLPKGFENFVGLPGKPGPKGEPGDPAPAREGLRAVGQKGDRGDPGIQGLKGEKGEPCSSC
SSAVAAQHLGPSTGAK

PF01391 // ENSGT00900000140804_4_Domain_5 (737, 797)

GDVGPPGLGVPGLPGKVGAPGPTGLKGEKG--NFGEAGPAGS-P
GPPGPVGPTGIKGEKG

ENSGT00900000140804_4_Linker_5_6 (797, 834)

EPCEPCPALFQHQEEDSHVVALPGPPGKKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKHG
KAGER-GLKGQKGDAGNPGDPGIPGTTGQPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GAMTNMAGQPGKP-GPKGDQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGIQGEPGP-PGV

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGSQGEPGAQGLPGTQGPPGPQGPPGPAGGKGAKGS-----P
GVKGATGPVGPPGASVSGPPGPRGQQGETGLPGARG-----MPGEKGSQGEKGEPGECSC
PSRGDPIFS---GMPGAPGL----W---MGSSWQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCL-GQTAHPAALLENGEKGAQGIPGVPGLDSCAR
CFMEREHPRAEEARVSGPPSPHHLPPAASWGCSHSPSIPLQGDNGEGDPGCAGSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLRGLTGEKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGSPGEKGES-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GPPGPPGSPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKPGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHIGP-PGPPG--QPGPAGISAVG
LKGDRGSPGERGLLGLPGQPGPPGHPGPPGEP-GMDGAAGKEGPPGKQGLYGPPGPKGDP
GPS

PF01391 // ENSGT00900000140804_4_Domain_17 (1744, 1802)

GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPAGSPGLPGVPGSM
G

ENSGT00900000140804_4_Linker_17_18 (1802, 1842)

DMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMVAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGSP
GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGVGIAGEIGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKNMKGPFG

---------------------------------------------------------MLT
SWAPGLWVLGLWATFSHGTNIGERCPTSQQEGLKLEHSSDPSTNVTGFNLIRRLNLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTVLLKKHTFRNTWYLFQV
TDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASV
HVDCISASSQPLGPRQSIRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPGGCPPETSKSRRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLMGRSIQKAE
RGTKVHQGTGV-----NECPPCAH---SARESNVTLGPSG---------------LKGGK
GERGLTG-PSGPKGEKGARG----------------------------------------
-------------NDCVRVSPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGDLGPPGLPGPTGQKGQKGEK-
GDGGLKGLPGKPGRDGRP-GEICVIGPK---------GQKGDPGFVGPEGLAGEPGPPGL
PGPPGIGLPGTPGDPGGPPGPKGEKGSSGIPGKEGPGGKPGKPGVPGTKGEKGDPCEVCP
TLPEGSQNFVGLPGKPGPKGEPGDPAPAWEGLGTVGLKGDRGDPGIQGMKGEKGEPCSSC
SSGVGAQHLGPS---------PGH

PF01391 // ENSGT00900000140804_4_Domain_5 (745, 801)

GLPGLPGTSGIPGPRGLKGEKG--SFGDTGPAGV-P
GSPGPVGPAGIKGAKGEPCE

ENSGT00900000140804_4_Linker_5_6 (801, 834)

PCTALSELQDGDMRVVHLPGPAGEKGEPGSPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKG-DGCTACPSLQ
GALTDVSGLPGKP-GPKGEPGPEGVGRPG----KPGQPG-------LPGVQ-------GP
PGPKGTQGEPGP-PGT

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1033)

GAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGP-----P
GPKGAIGPMGPPGAGVSGPPG-----------------------QKGSRGEKGEPGECSC
PSRGEPIFS---GMPGAPGL----W---MGSSSQPGP-----------------------
-----------------QGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGS----
-------LP-----IEKHLLKSICGDCAQGQTAHPAFLLEKGEKGDQGIPGVPGFDNCAR
CFIERERPRAEEARG---------------------------DNS

PF01391 // ENSGT00900000140804_4_Domain_12 (1306, 1363)

EGEPGCSGSPGLPG-
-PPGMPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGPSGEKGEL-GPPGSEGLPGPQ
GPAGPRGERGPQGSSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKAGAPGPPGPQAEKG----SEGIRGP--------------------SGLP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHLGP-QGPPG--QPGPPGLSTVG
LKGDRGVPGERGLAGLPGQPGTPGHPGPPGEP-GSDGAAGKEGPPGKQGLYGPPGPKGDP
GPAGQKGQAGEKGRSGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGNPGLPGLPGSM
GDMVNYDDIKRFIRQEIIKLFDERMAYYTSRMQFPMEVAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKSMKGPFG

---------------------------------------------------------MWV
SWAPGLWLLGLWATFSHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTYQKTWYLFQV
TDADGYPQISLEVNSQERSLELRAQGQDGDFVSCVFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPWRPLRPMGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSQVDAQLTGRISQKAE
KGAKVHRETGA-----DECPPCVHG---ARNSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGAQG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 560)

GPKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGIKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGLPGL
PGPPGIGLPGTPGDPGGPPGPKGDKGSSGMPGKEGPGGKPGKPG---VKGEKGEPCEVCP
TLPEGFQNFVGLPGKLGPNGEPGDPAPA------------RGDPGIQGIKGEKGEPCLSC
GLVAGAQHLASSTGA

PF01391 // ENSGT00900000140804_4_Domain_5 (736, 800)

GGEVGSPGFGLPGLPGTAGAP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPAGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQDGEIRVVALPGTSGEKGEPGRPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDMAGRPGQP-GPKGEQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGSQGEPGAPGLPGIQGLPGPRGPPGSTGEKGAQGS-----P
GVKGATGPMGPPGASVSGPPGRDGQQGQTG---ARG-----TPGEKGSRGEKGEPGECSC
PSRGDVIFS---GMPGAPGM----W---TGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGLDTCAQ
CFLSLERPRAEEAR---------------------------GDNNEGDPGCV

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYTGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQPGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDTGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGQCNPSDCFGAMPMEQQYPPMKTMKGPFG

---------------------------------------------------------MWA
SWAPGLWLLGLWATFSHGANTDAQCPPSQQEGLKLEHSSSLPANVTGFNLIRRLSLMKTS
AIKKIRNPK-GPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTYQKTWYLFQV
TDADGYPQISLEVNSQERSLELRAQGQDGDFVSCVFPVPQLFDLRWHKLMLSVAGRVASV
HVDCSSASSQPLGPRRPLRPAGHVFLGLDAEQGKPVSFDLQQAHVYCDPELVLEEGCCEI
LPAGCPPETSKARRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSQVDAQLTGRISQKAE
RGAKVHRETAA-----DECPPCVHG---AQNSNVTLAPSG---------------PKGGK
GERGLPG-PPGSKGEKGAQG----------------------------------------
-------------NDCVRISPDAPLQCAE

PF01391 // ENSGT00900000140804_4_Domain_1 (510, 561)

GLKGEKGESGALGPSGLPGSTGEKGQKGEK-
GDGGIKGVPGKPGRDGRP-GEICVIGPKGQ---------KGDPGFVGPEGLAGEPGLPGL
PGPPGIGLPGPPGAPGGPPGPKGDKGSSGMPGKEGPGGKPGKPG---VKGEKGEPCEVCP
TLPEGFQNVVGLPGKLGPKGEPGDPAPA------------RGDPGIQGIKGEKGEPCLSC
GLVVGAQHLASSTGA

PF01391 // ENSGT00900000140804_4_Domain_5 (736, 800)

GGEVGSPGFGLPGLPGTAGAP---GLKGEKG--NFGEAGPAGS-P
GPPGPVGPAGIKGAKGEPC

ENSGT00900000140804_4_Linker_5_6 (800, 834)

EPCPALSNLQNGKVRVVALPGASGEKGEPGPPGF

PF01391 // ENSGT00900000140804_4_Domain_6 (834, 889)

GLPGKQG
KAGER-GLKGQKGDSGNPGDPGMPGTTGRPGLSGEPGVRGPAGPKGEKG-DGCTACPSLQ
GTVTDMAGRPGQP-GPKGDQGPEGVGRPG----KPGQPG-------LPGVQ----GPPG-
--LKGVQGEPGP-PGR

PF01391 // ENSGT00900000140804_4_Domain_8 (977, 1034)

GVQGPQGEPGAPGLPGIQGLSGPQGPPGSTGEKGAQGS-----P
GVKGATGPMGPPGASVSGPPGRDGQQGQTG---ARG-----TPGEKGSRGEKGEPGECSC
PSRGDVVFA---GMPGAPGM----W---TGSSWQPGP-----------------------
-----------------QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS----
-------LP-----IEQHLLKSICGDCVQGQRAHPAYLVEKGEKGDQGIPGVPGFDNCAQ
CFLSLERPRAEEAR---------------------------GDNNEGDPGCV

PF01391 // ENSGT00900000140804_4_Domain_12 (1313, 1372)

GSPGLPG-
-PPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE-
----------PGPPGQPGYPGAMGPPGLPGIKGERGYAGSAGEKGEP-GPPGSEGLPGPP
GPAGPRGERGPQGNSGEKGDQGF--------QGQP-GFPGPPG-----------------
----PPGFPGKVGAPGPPGPQAEKG----SEGIRGP--------------------SGMP
GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM---GPPGFKGKTGHPGLP
GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGP-PGPPG--QPGPAGISAVG
LKGDRGATGERGLAGLPGQPGPPGHPGPPGEP-GADGAAGKEGPPGKQGFYGPPGPKGDP
GAAGQKGQPGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGSPGPSGSPGLPGVPGSM
GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA

PF01391 // ENSGT00900000140804_4_Domain_18 (1842, 1894)

PGRPGPPGKDGAPGRPGAP
GSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGA
TGPMGQQGIPGIPGPPGPMGQPGKAGQCNPSDCFGAMPMEQQYPPMKTMKGPFG