Query Results 

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-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVRQ-NGQWGTVCDDGWDIKDV
AVVCRELGCGAANGTPS-GILYEPPAENEQKVFIQEVSCTGTEDTLAQCEQ----EEAY-
NC------L-HNEDAGALCENP--------------------------------------
---------------------------------------EIPL-----------------
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-----------------------------------------SPV----------------
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----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGRCKGRVEVK-HQN---WWYSVCQTGWSLRAAKVVCRQLGCGRAV
RTQKRCKKLAQGQRSIWLSQMSCSGREATLQDCPSGPWGKS---TCIHDEDTWVKCED--
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-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFKDRKSYGPGVGRIWLDDVRCL
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSG--------------------------
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-----------------------------------------------MSLLL-TLILA--
-ICPGLGLL----------ESAPRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEVEQ-NGQWGTVCDDGWDLQDV
AVVCRELGCGIAKKSPS-GTQYKPLAEKDQSVLIQNVGCSGMEDTLAQCEQD---EDVF-
NC------P-HEEDAGASCEKP--------------------------------------
---------------------------------------ESSSSTGPES-----------
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----------------------------S---FSLAPEVPFFLV----------------
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----------------------------------------------------------PD
SVRL--A-----S

PF00530 // ENSGT00900000140803_2_Domain_6 (1034, 1137)

GPGHCVGRVEVE-HKG---QWSTVCKTGWNLQAAKVLCRQLGCGRAL
VAQRQCKETTQGQGSIWMSKMTCLGEEAMLQDCDSGPLK-N---SCTHHDDAWVECED--
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-----------------------------------------AFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKFCSGRLE
VLHKNDWGTVCDDSWGEQEDQVVCKQLGCGKPL--FSSSKTQKRYGPGVGRIWLDDVRCS
GKEKSLDQCKHRFWGHH---DCVHKEDVSVTCSE--------------------------
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------------------------------------------------MRGL--------
-ACL--------LAMLVGIQAIERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-SGRWGTVCDDGWDLRDA
EVACRVLGCGGALAAPG-GAFFGEG---TGPVWLSELNCRGNEGQLGICPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CVGQRAANSRE--DSMSLLDGDPWLALSGELSPSSEEPPITH
APQPAASSQN--GPRKKNPRPPKQTKSTRAPVLTNGAPHQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGEGPVWMDDV
GCGGGEEALRDCPRSPWGRSN---CDHTEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
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----------------PAPRIRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACKELGCGGALAAPGGAFF--------GEGTGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-AVQPTVP--AV
DSNSTAH-----R-LLST------------------------------------------
---------------SVGQMPGPAG-----PWPPSASPT-------APPEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDMRDSAVVCRELGCGRPR
QPDPAAGRFGWGAGPIWLDDVGCMGTEASLSECPAASWGKH---NCAHNEDVGVTCTGTP
GLDTISDPFSWSWLPGLGRDQDAWLPGELTTKPS----ASLTSSVPQKP-TKVPGKAPKS
TKKWVTKNARRPTTQPPGMPTTKHSRAPGTPTSLHPTAR------------------TSE
LPKRLTTEAPHRQTSHTTVRLTPRVPWEWTSEPVVSQSTQGPQEVTSEATTTE-NPQTSL
EPS-----G-ENT-EGSLESSQD---PATTPTAGVPV-PSGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGLWGTVCDDSWDIRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEMSLSDCPSGAWGKH---NCDHEEDVVLTCTGYTGDDDYPSWTWDPTSGEDLTKGTTV
AARPGHTLSWAT-TTNTEVPS---PATQNLPDT--DDQGGYESSWTWDT-PSGRGLF---
KGTPTTTKPGSTVTTSTSKSPGHPFPAPRAR--AGSPRKP-----TPERRPL---PTSA-
TT-----SSPASSSSPEPSGSRQ------TSGSWPQLIP-DS----KQEGTSSSPKPSLL
-----TPGLPSP--------------------ATFA-------LSTPNTSLLP--TRSPE
LSGSPTPTSPEG----------------LTSASSMLSEVSRLSPTSEL-TPG---PDTTP
----AP--EIIPE--------SSDSSDLPMNTRTPTQPF--------------------T
A-------------------------SHPTSIPQ--------------------------
------------------------------------------------------------
----LNTTSYPTIAPQPTTNPQQPRSPHPATS----------------------------
-------------------------------PQPPTNTH-----P-----SST--P-A-T
-PTESLPSSRKTELSSPT-----KPRLNSELTFE-EAPSTDASQTQNLEL---FLASESG
PSSPSPASNLDPLPTDAFKPPRSQT----------LHSAS--------------------
------DHLTQGPTPNHNPDPFGPCVSPLP-----PVRVMACEP-PALVELVGAVREVGD
QLQRLT------WVLEQDRQERQVLALGLAQLVEAAQGLGQLSETV--------------
---------------------------------KRLAEVA--------------------
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--------------------WPPSTPVPMTTTTEE--EERPLRGDV--------------
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-----------------------------------------QLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VNGTNHCSGRVEVLY
GQQWGTVCDDNWDLLDAEV-VCRQLGCGT-----ALSAASSAYF----GRGSDPIWLDDV
MCKGTEAALSECTAKPWGKHN---CGHGEDA------GVVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

SGF----------------
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-------------AKP--APLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VGGSTHCSGR-----IEVLYGQRWGTVCD--DG-WDL
ADAEVVCRQLGCGKALSAPHGAHF--------GQGSDP-------------IWLDDVSCI
---G-------TEAALSACKASPWGSHNC---RHGEDAGVVCAGFA--------------
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---------------------------------------------------------ELL
PVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGSNFCSGRVEVF-REQ---QWGTVCDDSWDLTDAQVVCRQLGCGEAI
S-APGSARYGQGTGKIWLDDVNCAGSETALTDCRAKPWGDH---NCNHGEDAGVVCSG--
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----------------------------T--------AEPA--SIRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GPSHCAGRVE
VFHDLQWGTVCDDSWDKAEANVVCRQLGCGAAISAP----GSARFGQGSGPIWLDDVSCV
GTEAALSQCQLQAWGSH---NCKHGEDAGVVC

ENSGT00900000140803_2_Linker_9_11 (1473, 1517)

SE--------------------------
-------PAP---VRL

PF00530 // ENSGT00900000140803_2_Domain_11 (1517, 1734)

VNGSN---FCSGRVEVFH-EQQWGTVCDDSWD-LTDAQVVCR--
-Q-LGC--------GEAISAPGSA------------------------------------
------------------------------------RY----------GQGTGKIWL---
-DDVNCAGSEIA------LAECR--------VKPWGDHN---CNHGEDAGVVCS------
------------------------------------------------------------
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--------------------------------GTV--------------------RK---
--------------T---------------------------------------------
----IW------------------------------------------------------
--CKR--T----------------------------------------------------
-GLTWS---------SQ-------------------------------------------
-------------TSAEKASIT----------------------EPAPIRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VNGPNLCTG
RVEVF--HDHQWGTVCDDGW----------DKAEANVVCRQLGCGA-------AISAPGS
AHFGQGSDPI-------WLD--DVSCVGTEAALSQCQFQTWGSHN---CKHREDAGVVCS
DNMKFLFLS-------LAGQ-IALYTEQEWCSVSQSGSSAERKINPIFIINQHLICE---
-----CEIGSLH-----------------TSNAEHAGEYEVDYGRSPAH-----------
PECPL---HPLGTLVG-------------TGT-AEAAPLRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2662)

VNGPSRCAGRVEVLLGQQW
GTVCDDSWGLSDAAVVCKQLGCGTAMSAPGSAYFGQGFGRIWLDDVRCSSSESALSECAA
RPWGVHN---CNHGEDAGVVCSAN-------------------------------EER-Q
AVTQSNFR----PTSEVSLTVLTVKL-------VFSFVASTLLQKR--------------
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------------------------------------------------MRVL--------
-ACL--------LVALMGTQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGGERQLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 526)

CAGQRGTDSRDHDDPPSVLDGDPWPGLAGELSPGSEEAPVTP
APRPAGTPQS--GSRKKSPRLPKPAKSTRAPVLTAGAPRQERLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VSGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

TG-----------------
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----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGTVCD--DG-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--AA
GSNSSGPRGAPSR-SPPP------------------------------------------
---------------TASQAPQMPG-----VSVPPAPPT-------FLQEPGPD--AGSP
QLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1136)

-AGPSRCSGRLEVW-HAG---RWGTVCDDGWDLRDTAVVCRELGCGGPR
QSDPTAGRFGWGAGPIWLDDVRCTGTEAALADCLAAPWGKH---NCAHNEDVGVTCAGTP
GLDSISDPFSWSWIPGLGRDPDAWLPGELATKPS----ARQTPSIPEKT-TKAPGKMPKS
TKKWVTKNAKRPTTQPPAMPTTKHSRVSGTQSPPELTSRTT--STLATGAS---RRPTSE
FTTRLTTQAPRRLTSHTTVTRTSRAPRERTSKTVATLATQGPRLVTSEAT---------V
EPS-----A-ELPGQGSPESSTD---PAPSPTGAAVP-PAGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-GPNRCAGRLE
VWHAGQWGTVCDDGWDLRDGMVTCWELGCGRVRPRV----GKTHYGPGTGPIWLDDVGCK
GSESSLSDCPARAWGQH---NCDHEEDVGLTCTGYADEEDYPPWTWDPTSGEDLAKGTTS
AGVPGHTLSRET-TGSPGAPT---PATRRLPST--GDKDCREPSRTGDT-PSGGVPA---
KETPTAATPGP---PGTTRSSGHPSLAPRLRGDTGSQRRR-----WPERR-LR--PTTA-
RTK-PAAPSPPASAAPGPADPPL---T---SASAPPLIR-TAAS--TPEATPDATSAVPP
-----SPVAASR--GSAHR---------TSTSPGLT-------GPSPDAAAAP--APTSR
LSPTPPPTAPKE----------------LTSDPSAPAAATHLSPTSGL-TPD---PDKAP
GRGTSPQPSTVPE--------PSSSPDRSTGPHPTTAPYSTMTSHPEPTSHPTTAPYSSM
TSHPAATSHPTTAPYSTMTSH-PT------------------------TALYSTMTSHP-
----------APTSHPTTAPYTIMT-SHPA------------------------ST----
------------------------------------------------------------
-------------------------------------SH-----PT--------------
------------------TAPPVKPSLHPQLTFTG-APRPSTS--------------PAS
ESSLSPAPSMDIPSTENFKAATSQSP----------------------------------
--EPPPDHLSLGPAPSPSSGPLGPCEAPVP-----PVRVMACEP-PALVELVAAVRDVGS
QLQRLT------QALERDQQDRRALGLGLTQLVEAAQGLGQLGEVV--------------
---------------------------------KRLAEVA--------------------
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--------------------WPPTTPVPTTTTPEW--EERPLRGDV--------------
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PF00530 // ENSGT00900000140803_2_Domain_2 (367, 440)

VGCGSALSAPV-GATFGQG---AGQIWMDDVICVGTEASLSLCW-IT--SWGSH
NC------G-HREDAGVEC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SEP--------------------------------------
----------------------------------------TQVRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VNGSSRCSGRIEVHH
NQRWGTVCDDGWDLADAEV-VCRQLGCGT-----AVSAPGKALF----GQGHDPVWLDEV
NCTGTEGAITECSLKRWGDHN---CKHDEDA------SVVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

SD-----------------
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-----------------PTELRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

ANGPNRCAGR-----VEVLHQEQWGTVCD--NA-WGM
EHAKVVCRQLGCGTPIYAPGWARF--------GRGYDP-------------IWLEKVTCS
---G-------MESALSECTVQSWGQHSC---HHGEDASVVC

ENSGT00900000140803_2_Linker_4_5 (883, 884)

T

PF00530 // ENSGT00900000140803_2_Domain_5 (884, 1017)

GTEDSLSKCRARPK---
----------------------GV------------------------------------
------------TGCHHGED-------------------------ASV------VC

ENSGT00900000140803_2_Linker_5_6 (1017, 1032)

SDPT
EVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGSNHCSGRVEVL-HNQ---RWGSVCDDGWDLNDAEVVCRQLGCGTAI
W-APSAARFGQGYEPIWLDDVNCTGSEAALSECRARPWGVS---NCNHKEDAGVVCIGKR
LAFLC-GAA---------------------------------------------------
------------------------------------------------------------
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----------------------------L--------EGVMLEALRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GSNSCAGRVE
VLHKQLWGSVCDDGWDTEDAAVVCRQLGCGTVLSAP----GRAWFGRGRNAIWLDDVNCT
GTENDLLECSARPWGEH---NCNHGEDAGVVCSG--------------------------
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PF00530 // ENSGT00900000140803_2_Domain_6 (1061, 1137)

GWNLKSAKVVCRQLGCGRAI
NTQKPCDKSTQGKGPIWQSRISCLGQEVVLQDCQSRPWEKN---NCTHAEDTWVDCED--
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-----------------------------------------PLEWKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GHSRCSGRLQ
VLHHGMWGSVCDDGWGEQEDQVVCKQMGCGKPV--SPSMKERKIFGPGVGRIWLDDVDCS
GNEQSLELCRHRFWGRH---DCTHEEDVAVICSD--------------------------
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------------------------------------------------MRVL--------
-AGL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLSVELSPSTEEPPVTH
GPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTIGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MMSQAPGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKYAKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTAE
FTRRPTTEAPRRWTSHTTATLTPQAPRERTTKTTAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSASTTR-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
ARVPGHTLPWGT-TRRTGISS---PATRRLPDT--GGKDGYKLPWTWDT-PSGRGLG---
EGTPTAGKLGPTLGAGTTRSPGSP-PTPRVHGDTGSARKP-----WPERRPPR--PAAT-
RTA-PATPSPGPSASPGPPGPAL---T---SDCSPELTP-HPAL--TPEATSDPPDTSPP
-----TPDPTSR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTLE
PSPTPLPTLPKE----------------LTSDPSTPLEVTSLSPTSEQ-IPE---SDTTP
DLDTTPYSSTVSE--------YSRSPAPSPSPHPTTIPDPT------MTP------NHTT
TPNPTVTPQFPTTTHPTTTPQ-------PTTISYSTMIPDPTTTPQPF------------
------------------------------TTMQPTTTPHP-------TTPHPTTTPHPT
TTTHSTMIPDPTTTPQPFTTMQPTMIPHPT-TPYPTTTPHPTTTPHPTTTPHPIT--T--
--PDPTTT-----------------PHPTTTPDPTTTPH-----P-TTTPDSS--STPII
-TTKSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTMSP----DPHLSLIAHP
LDHPPLDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRVVEMA--------------------
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--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
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-----------------------------------------------MVLLF-FLTLA--
-IGPGLGFS----------DHPHGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGHNRCNGRVELQK-NGQWGTVCDDHWTNETV
AMVCQELQCGPAVKVWA-GRLFPPKAPKDQPIW--NLKCQGTEKTLAECEE-----DTVE
CD------D-HYEDAGAICKEP--------------------------------------
---------------------------------------L--------------------
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-------------------------------------------N----------------
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----------------------------------------------------------IE
ELRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPNRCIGRVEVK-YAE---KWGTVCNADWTLQHAKILCQELGCGRAI
LTKGCCNKNQQGTGDIWPGQVKCQGSEESLRDCPVVPMEKN---NCTHKDDTWVYCEE--
------------------------------------------------------------
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-----------------------------------------QFAMRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VD-GESKCSGRLE
VLHKGVWGSVCNDGWGEKEDQVVCQELHCGKAL--SQKPRARKSFGPGKGRIWLDDVRCQ
GTETSLIQCQHRFWGYH---DCTHREDISVLCSEK-------------------------
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------------------------------------------------MRVL--------
-ACL--------IAALMGIQAVERLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

ADGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---TGPVWLSELACRGSEGQLGLCPHR---GWKAH
IC------S-HEEDAGVVC

ENSGT00900000140803_2_Linker_2_3 (440, 533)

AGQRVANSRDGDDPPPILERDPWPGLSEELNPGSEEPPVTH
APRPAGTPQN--NSRKKSPRPLKQPKSTRAPVLTAGAPRHGQLGLTWGPPGC

PF00530 // ENSGT00900000140803_2_Domain_3 (533, 642)

LAGLQCGR
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

TG-----------------
------------------------------------------------------------
----------------PAPRLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

ADGPHGCAGR-----LEVWHSGRWGTVCD--DA-WDL
RDATVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAPAPAV
DSNRSLPREVASR-PPAP------------------------------------------
---------------TGSQAPGTAG-----ISPPPASPT-------VPREPGPE--AGSP
QLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSRCAGRLEVW-HNG---RWGTVCDDSWDLRDSAVVCRELGCGRAR
QQDPAAGRFGWGAGPIWLDDVGCLGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTDTS
GLDSISDPFSWSWIPGLGRDPDAWLPGEPATKPP----AKLTPSLPEKTTTKAPGKTPKS
TKKWVTKNARRPTTQPPVVPTTKHSRVMGTQRPPELTSRTTT--TLTTEAS---RRTVSE
STAKMTTEVPHRMTSHTTATRTPRVPRERTAKTVATSTTQSPREMTSDAMVKR-TPLVST
EPS-----A-ETPAQGSPESSKD---PAPSPTGSTAGGSAGPFRVRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

AD-GPNRCAGRLE
VWHAGRWGTVCDDSWDLRDSTVACWELGCGRVRPRV----GKTHYGPGTGPIWLDDVGCK
GIEASLSDCPAGAWGQH---NCDHEEDVGLTCTGYADEDDYPPWTWDPTSGEDLAKGITT
AGVPGHTLSWAI-TKSPGTPS---PATRSLPNT--GDEDSYEPSRTLDT-PSGGALP---
KGTPTAGRAGSTLTAGTTRSAGHPSPAPRIRGDTGSLRKP-----WPERRLQH--TTTA-
GTA-PPAPSPAPTASPEPSGPLV---T---SNSVPEHIS-EAAS--TQEVTSDPADTLTP
-----SPDLASG--MNSDL---------TLTTPGLT-------LSTPDAAVIP--ALTPD
LSPTPPPTLPKE----------------LTSDPSAPVVVTHFFSTSEL-TPE---SDTTP
NLDTASYSNTVPD--------HSRSPDPSTSPHPTSTPHSTLTSHPSMTSQP--------
----------MTTPHSTT------------------------------------------
-------------------------------------------------------TPQPT
TTLQPTTTPQPTTTPQPTTTPQP-------------------------------------
------------------------------------------------------------
-------TTARTELLSPTRAPTVKPSLYPWLTST-GSSHLSISQMASLAP---LPASESS
HSRPSPASSMDILSTEDFEPPRSQSH----------------------------------
--QPLPDHLTPRPTPGQSPDPFGPCVAPPP-----PVRVMACEP-PALIELVAAVRDVGG
QLQRLT------QVLEQEQQQRQALGLGLTQLVEATRNLGQLGEVV--------------
---------------------------------KRLAEGA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTSAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MET--VL---FLLV---WL----
-----------C-----GVANSAPIRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VDGPNHCAGRLEVLW-KQQWGTVCDDSWDISDA
TVVCRQLDCGKPLSAPG-SAHFGQG---TGPIWLDDMKCNGTEVDLSACR-TR--TWGEH
NC------N-HGEDASVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SGNN-------------------------------------
------------------------------------K--TVQLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VNGTDHCSGRVEVLY
GQQWGTVCDDSWDLIDAEV-VCRQLGCGT-----ALSAASSAYF----GRGSDPIWLDDI
MCKGTEAALSECTAKPWGKHD---CGHGEDA------GVVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

SGF----------------
------------------------------------------------------------
-------------AKP--APLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 882)

VDGSTHCSGR-----IEVFYGQHWGTVCD--DG-WDL
ADAEVVCRQLGCGKALSAPHGAHF--------GQGSDP-------------IWLDDVSCT
---G-------TEAGLSTCKASAWGSHNC---GHGEDAGVVCAGLA--------------
------------------------------------------------------------
---------------------------------------------------------ELL
PVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGSNFCSGRVEVF-HEQ---QWGTVCDDSWDLTDAQVVCRQLGCGEAT
S-ATGSARFGQGTGTIWLDDVNCAGSETALTECPAKPWGDH---NCNHGEDAGVVCSG--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------A--------AEPA--PIRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GPSHCAGRVE
VFHDRQWGTVCDDNWDKAEANVVCRQLGCGAALSAP----GSARFGQGSDPIWLDDVNCV
GTEAALSQCRFPGWGSH---NCKHGEDAGVVC

ENSGT00900000140803_2_Linker_9_11 (1473, 1518)

SD--------------------------
------IPRAAP-LQLT

PF00530 // ENSGT00900000140803_2_Domain_11 (1518, 1733)

NGPS---RCSGRVEVFY-GHQWGTVCDDNWD-ISDAEVVCQ--
-Q-LGC--------GRALSTATSA------------------------------------
------------------------------------SF----------GEGSGPIWL---
-DDVNCTGAETS------LSKCE--------TSLWGAHN---CNHGEDAGVVCL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------GVP--------------------EP---
--------------APVRL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2237)

VNG----------------------------SNFCSGRVEV
FHEQQWGT---------------------VCDD----SW-----------DLT--DAQV-
-VCRQ--LGCGEAI--------------------------------------------ST
PGSARFGQGTGTIWLDDVNCAGSETA------------LIECQVRPWGE-----------
H---NCNHGEDAGVVC

ENSGT00900000140803_2_Linker_15_16 (2237, 2272)

SG--IA----------------------EPAPIRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VNGPNLCTG
RVEVF--HDHQWGTVCDDNW----------DKAEANVVCRQLGCGA-------ALSAPGS
AHFGQGSDPI-------WMD--DVSCVGTEAALSQCRFRGWGSHN---CKHGEDAGVVCS
G-----------------------------------------------------------
------------------------------------------------------------
-------------------------------T-AEAAPLRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2662)

VNGPSHCAGRVEVLHSQQW
GTVCDDSWDLSDAAVVCQQLGCGTAMSAPGSAYFGQGYGRIWLDDVKCSSRESALAECAA
RPWGVHN---CNHGEDAGVICSG-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPAFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVKQ-NGQWGTVCDDGWDIKDV
AVVCRELGCGAANGTPS-GILYEPPAENEQKVFIQEVGCTGTEDTLAQCEQ----EEAY-
NC------L-HNEDAGALCENP--------------------------------------
---------------------------------------ESPF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---QWYSVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKPGQGQRSMWLSQMSCSGREVTLQNCASGPWGKS---TCIHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDELCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFKGRKSYGPGVGRIWLDDVHCS
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-----------QLSSHIFSESSSRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGDHRCEGRVEVQR-YGEWGTICDDGWDIKDV
AVVCRELDCGVAKRALS-GTLFGPPTQQQQKIFIQQVKCHGMEENLSQCEEE----DAF-
DC------T-HDEDAGVVCETP--------------------------------------
---------------------------------------PLSFP----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------IV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGHKRCQGRVEVK-QQG---QWGTVCKGSWNFAAAKVVCQQVGCGRAI
LTRKCCNKATQGQGPIWPRKVSCSGKEISLQDCPSEVWEKN---NCTHDEDMWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1472)

VG-GDSPCAGRLE
VLHKGEWGTVCDDDWGEMADQVVCRQLGCGASL--SPSVKFRRRFGPGVGRIWLDDVACS
GNERSLEQCRHRFWGHH---NCKHTEDVAVVCAG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

PF00530 // ENSGT00900000140803_2_Domain_3 (556, 642)

DAGV-VCRHLGCGT-----ALSAPGGARF----GRGSERIWLDDV
NCKGTEAALSECTARPWGDHN---CNHGEDA------SAVC

ENSGT00900000140803_2_Linker_3_4 (642, 748)

SDS----------------
------------------------------------------------------------
-------------APPGEIPLRLGEWP

PF00530 // ENSGT00900000140803_2_Domain_4 (748, 883)

RRCAGR-----VEVLHGQQWGTVCD--DS-WDL
SDAGVVCRQLGCGTALSAPGGARF--------GRGSES-------------IWLDDVNCT
---G-------TEASLSECKSRPWGDHNC---NHGEDASAVCSDSTS-------------
------------------------------------------------------------
--------------------------------------------------------PGEI
PLRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

NGSSRCAGRVEVL-HDQ---QWGTVCDDSWDLTDAGVVCRQLGCGTAL
S-APGGARFGRGSERIWLDEVNCKGTEAALSECTARPWGDS---NCTHGEDASAVCSD--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------S--------TTPGEIPLRLAN

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-GSSRCAGRVE
VLHDQQWGTVCDDSWDLTDAGVVCRQLGCGTALSAP----GGARFGRGSERIWLDDVNCK
GTEAALSECKSRPWGDH---NCNHGEDASAVCSG--------------------------
-------NSLLC-HLLA-G-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LXXXXXXXXXXWLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

ADGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGGEQQLGLCPHR---GWKAH
IC------S-HEEDAGVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

AGQRVSDSRDWDDSPSVLDGDPWPGLSGELSPGSEEAPVMP
APRPAGTPQS--GSRKKSPRPPKPAKSTRAPLLTAGAPRQERLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VSGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCLRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

TG-----------------
------------------------------------------------------------
----------------PAPRLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

ADGPHGCAGR-----LEVWHSGRWGSVCD--DA-WDL
RDAAVACHELGCGAALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--AV
GSNS-------SR-PPPP------------------------------------------
---------------TVSQAARIAG-----ISPPPASPA-------APQEPGPE--AGSP
QLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSRCSGRLEVW-HGG---RWGTVCDDSWDLRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVRCVGTEASLADCPAAPWGKH---NCAHNEDVGVTCTGTP
GLDSISDPFSWSWIPGLGRDPDARLPGEQVTKPY----PRRTPSVHEKTTIKAPGKIPES
TKKWVTKNAKRPTTQPAVIPTAKHSRAQ---SPPELTSLTTP-T--------------SA
FTTRLTTEDPHRLTSHTTERRTPRVPRERTSKTLATPTTQGPRELTSEAT---------M
EPL-----A-EIP-GGSPESSKD---PAPSPTG-----ASGLFRVRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

AD-GPNRCAGRLE
VWHAGRWGTVCDDSWDLRDGMVACWELGCGRVRPRV----GKTHYGPGTGPIWLDDVGCK
GSEASLSDCPARAWGQH---NCDHEEDVGLTCTXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX---XXXX-XXXXXXXXXXXXXXXXXXXX--XGEDGYEPSWTWDT-PSGEVPA---
KGTPTAGIPGPSGTAGTIRSPGHPSLAPRVRG----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-FLILA--
-ICTRPGLL----------ESPFTVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGSHRCEGRVEVEQ-EGRWHLVCDDDWDKNDV
AVVCRELGCGAAKKALS-GFLYKPPPEQWQEFLFQNVNCSGMEDALAHCEKD---EGDI-
DC------S-IEEAAGALCENP--------------------------------------
---------------------------------------DS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------PV----------------
------------------------------------------------------------
----------------------------------------------------------FE
EVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGRCKGRVEVK-YQD---QWSPVCKTGWNLRAAKVVCHQLGCGRAI
LAQKHCSKAAQSQGPIWLNQISCSGKETALQDCPSEPWGKN---NCTYEDHVWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKRCSGRLE
VFHKGVWGSVCDDGWGKKEDQVVCKQVGCGKSL--SPSSKVRKSYGPGVGRIWLDDVRCS
GDEQSLEQCKHRFWGYH---DCTHKEDVAVICSE--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTGFPVADSGSPEVAQLRLS

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 440)

NGSSRCAGRVEVLH-DQQWGTVCDDGWDLTEA
RVVCRQLGCGTALAAPH-GSRFGHG---TGRIWLDEVNCTGTEAALSECR-AK--PWGEH
NC------N-HVEDASVEC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SEL--------------------------------------
----------------------------------------APIRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VNGPSPCAGRVEVLH
DQQWGTVCDDGWNLTEAGV-VCRQLGCGT-----AVAAPHGSRF----GHGTGRIWLDEV
NCTGTEAALSECRAKPWGEHN---CNHVEDA------GVEC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

SD-----------------
------------------------------------------------------------
-----------------PGLLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VNGPNRCAGR-----VEVFHSRQWGTVCD--DD-WDL
SDVGVVCRQLGCGTAVAAPGGALF--------ERGSDT-------------IWLDDVNCT
---G-------SEAALSDCRARPWGNNNC---HHGEDAGVVCSGNPPQLLLSCL--R---
----------------------GG------------------------------------
------------LCVPVGHA-------------------------PSSLLGPVCSPDSAL
PHRA--S-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

NGSSRCAGRVEVL-HDK---QWGTVCDDGWNITDAGVVCRQMGCGTAV
S-APGKAHFGLGHGPIWLGDVNCTGTEAALSECWARPWGKNI--NCHHGEDAGVVCSE--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AVQLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GPNRCAGRVE
VFHGHRWGTVCDDGWDLQDARVVCQQLGCGTASSAP----GRSHFGRGTDIIWLDEVQCT
GTEAALTVCRARPWGIH---NCHHGEDAGVVC

ENSGT00900000140803_2_Linker_9_11 (1473, 1517)

SEE-------------------------
----------SQ-LRL

PF00530 // ENSGT00900000140803_2_Domain_11 (1517, 1734)

VNGSS---TCSGRVEVLH-NQQWGTVCDDGWD-LIDAEVVCR--
-Q-LGC--------GTALLAPRAS------------------------------------
------------------------------------RF----------GQGSDPIWL---
-DDVQCTGTEAA------LSACK--------AKPWGTHN---CQHREDASVVCS------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------VYLRL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2237)

VSG----------------------------PNRCTGRVEV
LHDQQWGT---------------------VCDD----GW-----------DIT--DAGV-
-VCWQ--LGCGTAV--------------------------------------------SA
PGGARFGQGDYRIWLDDVQCTGTEAA------------LTECKARPWGD-----------
N---NCHHREDAGVVC

ENSGT00900000140803_2_Linker_15_16 (2237, 2272)

SE---------------------------ADQLRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VNGSSRCTG
RVEVL--HNQHWGTVCDDSW----------DLTDATVVCRQLGCGT-------ALSAPLR
AHFGRGSDPI-------WLD--DLRCTGTEAALSDCRARPWGDNN---CNHGEDAGVVCS
GDPPPSHLVPL---NS--------------------------------------------
--------------------------------------ALAHHAPSPS-----------A
APCP------------------------GASI-SEADQLRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2662)

VNGSSRCNGRVEVLHNQHW
GTVCDDSWDLTDATVVCRQLGCGTAISAPRGSYFGRGSDPIWLDDLRCTGTEAALSDCRA
RPWGDNN---CNHGEDAGVVC

ENSGT00900000140803_2_Linker_18_19 (2662, 2703)

SDFPLP---------------------------EVAPSR
LA

PF00530 // ENSGT00900000140803_2_Domain_19 (2703, 2809)

DGPSRC-----AGRV--EVFHGLQWGTVCDDDWDLTDAGVVCRQLGCGTALAAPHGAH
FGRGSDPIWLDDVQCTGAEVALSKCRARL---WGDGNCQHGEDAGAVC

ENSGT00900000140803_2_Linker_19_20 (2809, 2832)

SVTRPSEIPSLM
PCRDEVAVLRL

PF00530 // ENSGT00900000140803_2_Domain_20 (2832, 2933)

MNGPSRCAGRVEVLHNRQWGTVCDSGGWDLHSAAVVCRQLGCGKVLAAP
HGAYFGTGNNRIWLDGVRCTGAETALSECKARPWGT---HDCDLGQDASVVCSG------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MA-LL-FLILA--
-ICTGSGLS----------DSQTGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VRGPHRCEGRVEIER-MGHWGTVCDDGWDMKDV
GVLCRELGCGPAKGTPS-GYLYKPSAGNEQRVLTQLVNCTGMEKMLSECEQD---EDVF-
DC------S-HKEDAGALCENP--------------------------------------
---------------------------------------DIPL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
SVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPGRCKGRVEIQ-YQG---KWNTVCKTGWNLKSAKVVCRQLGCGRAI
NTQKPCDKSTQGKGPIWQSRISCLGQEVVLQDCQSRPWEKN---NCTHAEDTWVDCED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PLEWKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GHSRCSGRLQ
VLHHRMWGSVCDDGWGEQEDQVVCKQMGCGKPV--SPSMKERKIFGPGVGRIWLDDVDCS
GNEQSLELCRHRFWGRH---DCTHEEDVAVICSD--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALLGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWY-GGRWGTVCDDGWDLRDA
TVACRELGCGGALAAPG-GAFFGEG---TGPVWLSELACQGREGRLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVADSRD--DSTSPLVGELWPGLSAELSPASEEPPMTH
APRPAGSPQN--SPRKKSPRPPKQTKSTRAPLLTTGAPRQDRLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDATV-ACRELGCGG-----ALAAPGGARF----GPGLGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWQGGRWGSVCD--DA-WDL
RDAAVACRELGCGAALAAPGGAFF--------GEGSGP-------------IILDDLRCL
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVASTAP--AG
DRNSSASGEAAPG-SSPS------------------------------------------
---------------TSSRAPGTAG-----SSPPPASPT-------AAREPGPD--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDTQDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVGCVGTEASLADCPAAPWGKH---NCAHNEDVGVTCTGSP
GLDTIADPFSWSWLPGLGRDRDAWLPGELATKPS----ASLTSSVPEKTTTKAPGKTPKS
TKKWVTKNAKRPTTQPPRMPTTKHPRGLGTQSSPELTSQTK--T-LTTEAS---PKRTSE
LPKRLPTEAPHRWTSYLTSKTTPRALWEWPSGTTTTLSPQGPREMTSETTIEQ-IHQASL
EPS-----A-ETPA--------------SSPTASISR-ESGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVVCWELGCGKVRARV----GKTHYGPGTGPIWLDDMGCK
GSETSLSDCPSGGWGKH---NCDHEEDVGLACTGYTDDDDYPSWTWDPTLGEDLAKGATT
APGPGRALPWGT-TRHPGISS---PAARRPPVT--GGQDGYKLSGTWDT-PLDRSPV---
KGTPTTARPAPTPFSGTTRHPGHPSPAPRARGDTGSPRRP-----GPDHRLLR--PTAA-
RAA-PPTRRPAPSASPGPP---L---T---SD-----------------STSVPPGTSAP
-----TPDLPSS--TTPDL---------AP------------------------------
-APTSLPTAPQE----------------LTSEPSAP---------PEG-TPG---SDTTP
DLGTATG--------------TSGSPERSTSPHPTTASYSTTA-----------------
--------------------------------------PNPTTAPIPTTA----------
------------------------------------------------------------
--QYLTTTPLPTTTPLPTTTPLPATSPH--------------------------------
----------------------------HTTPPPPTISD-----P-TRPPNPS--SSPVI
-TTQSLATSPGTEFPSSTPAPRVMPSLHPQVTSK-GAPHTPTSQMWSPAP---SPASEAS
PSRFPPASSTDPLSTKDFRTPRSQNPTLTPPQTQTPAPASSPTVIS----DLPLPPTSHP
LDQPPLDHLPLGPSPGQTLDPLGPCASPAP-----PMRVMACEP-PALVELVAAVRDIGG
QLQRLT------WVLEQDLQERQALGLGLAQLVEAAQGLGQLGETV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPIPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALMGIQAVERLLL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

ADGPHECAGRLEVWH-AGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGSEGRLGLCPHR---GWKAH
IC------S-HEEDAGIVC

ENSGT00900000140803_2_Linker_2_3 (440, 529)

AGQRVAANSR--ESAPLVGGDLWLGLSREFSPGPEVPPTTS
VPRLVGSSQNSGGSRKKSPRPPKQAKSTRAPVLTTGAARQGLMHWSQV

PF00530 // ENSGT00900000140803_2_Domain_3 (529, 642)

PHSCVGRLEVWH
AGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

TG-----------------
------------------------------------------------------------
----------------PAPRLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

ADGPHGCAGR-----LEVWHAGRWGTVCD--DA-WDL
RDAAVACRELGCGAALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPSRAWSQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TA
GNNNSTSR------ALPP------------------------------------------
---------------TVTQTLWTAG-----ILPPPASPT-------VPPEPGPA--AGSP
HLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSRCSGRLEVW-HDG---RWGTVCDDSWDLRDSAVVCRELGCGGAQ
QPDPPAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGTP
GLDSISDPFSWSWIPDLGGDRDAWLPGQLATKPS----ARLIPSAPEKTTTKAPGKMPKS
TKKWVTKNARRPTTQPPVMPTTKYSRGLGTQNPLELTSRTT------------------T
FTMRLTTEAPHRSTSYTTATLMPQAPRELTSKTLATLTTQGHREMTSEATIKQ-IPQASM
EPS-----S-EILAEGSPESSKD---SSPSPTGTSTG-ESGPFRVRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

AD-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDAAVACWELGCGRVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPAGAWGKH---NCDHEEDVGLTCTGYTDDEDYPPWTWDPTSGEDLAKGTTA
ARAPGLTLSWGT-TRSPGAPS---SATRHLPDT--GDKNNYELSWTWDT-PSRGDVA---
KGTAAAGIPGISITTATTRSPGHPFPTWRVHGGTGSARKP-----CPERRLRPAAT----
RTA-LPTPSPAPPASPGPPGPLVT------SDFAPQVTSEPSAS--RREVTSYPPDTSTP
-----TPDPASW--MNP----------------------------TPDSAVVS--DLTPE
LSPTPPPTLPKE----------------LTSDPSALRR-DHSSPTSEL-TPE---SHTRA
DLDTTSYPDTITE--------PSGSPDPSTSPHPTTPSTSTTQ--------------PST
SLHPSRSPHRTSTTRPGRDPS---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------TPSH--------------------I
-PGCRALGSF--------------------------------SQPRSSSP---L------
-QGFLPAPSN-------GPTVPNQSLKLTSPPMQNPLSASDSTVSP----DLHLFPWP-T
LGSTSPCHISLGPTSGQSP-PFGPCVAPTP-----PVRVMACEP-PALVELVATVRDVGA
QLQ-LT------QALERDQQERQALGMGLSQLVEATRGLGQLGEAV--------------
---------------------------------KRLAEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WAPSTPSPTTTTPEEEEEERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-NLIL---
AIFIRPGLS----------ESPPRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGAHRCEGRVEVEY-NGQWGTVCDDGWDLKDV
AVVCQELGCGAAKITRS-GALYKPPASNEQPVLIQGVNCSGMEDTLTKCKTD---EYVL-
EC------S-HEEDAGAVCENP--------------------------------------
---------------------------------------ENSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PLV----------------
------------------------------------------------------------
----------------------------------------------------------PE
SVQL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGRCQGRLEMI-HRG---QRSTVCKAGWNLRAAKVVCRQLGCGKAL
LTQRHCNKITQGKAPIWKSQILCSGQETDLQHCLFRPWE-N---NCTHDEDTWIECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AFELRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1472)

VG-GDSLCSGRLE
VLHKGVWGSVCDDGWGEEEDQVVCNQLGCGESI--LPSSKARKSYGLGAGRIWLDDVVCS
GEEPSLEFCLHRLWGYH---DCTHKEDVAVICDSDT------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------ERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHSCAGRLEVWY-SGRWGTVCDDGWDLRDA
AVACRVLGCGGALAAPG-GAFFGEG---TGPVWLSELACRGSEGQLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CVGKETQTPHMVM-----APGAPKSLVLRCLIP---YPHHHP
PNFPAANSQN--GPRKKNPRPPKQTKSTRAPVLTNGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GSRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQTLRDCPRSPWGRSN---CDHTEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDATVACRELGCGGALAAPGGAFF--------GEGAGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-DVQPTAP--AA
GSNTSVPR------ILST------------------------------------------
---------------SAGQTPGPAG-----RWPPPVSPT-------APPEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDGWDMRDSAVVCRELGCGGPR
QPDPAAGHFGWGAGPIWLDDVGCVGTEASLSECPAASWGKH---NCAHNEDVGVTCTGTP
GLDTISDPFSWSWLPGLGRDQDAWLPGELATKPS----PSLTSSVPEKT-TKSPGKAPKS
TKKWVTKNAKRPTTQPPGIPTTKRSRVPGTPSTPNLTPRT------------------SE
LPKRLTTEAPRRQTSHTTVKLTPRVPWEWTSETATSQSPQDPQDLTSEATITQ-TPQASL
EPS-----G-ESP-EASPESSRD---PAPTPSAGAPM-PSGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNSCAGRLE
VWHAGLWGTVCDDSWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GTETSLSDCPSGPWGKH---NCDHEEDVVLTCTGYTDDDDYPSWTWDPTSGEDLSKGPTV
AAQPGHAPSWAA-TRNPQVPS---AGTQRLPDT--GEGLDRELVWAWPS-TTGLTPGSVT
--TPD-------------------------------------------------------
------------------------------LGTTPEIVP-ESS------GTSD------L
PMSPRT------------------------------------------------------
--PTQPLTAPHP------------------------------------------------
--TTTSEPTTVPE--------PTTTPEP--------------------------------
-----------------------------TTTPESTSVPHPTTTLKPTTALEL-------
----------------TTTPELTSI-PHPTTAPEPTTTPEPTTTPEPTTTPEPTSVPHPT
TTLKPTTIPKLTSVSHPTTTPEPPKASHPTVTP---------------------------
--PQHTTN-----------------PQFPRTPHPTTASQ-----PSPNLSHAS--SAPAT
-AAKSLPSSPETDFPSLAPEPRVEPGPHPGLTFM--------------------------
-------HSMDPLSTEVFKPPSSQSPKLTSPSVQTSRSAPDPTVAP----DLHLA-MAPP
LEQPPPDHLTQGPPPHHNPGPLGPCVSPAP-----PVRVMACEP-PALAELVAAVREVGD
QLQRLT------RVLEQDRQERQVLGLGLLRLAEAAQGLGQLTETV--------------
---------------------------------KRLAEAA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------RPPSTPVPAFTTTTE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------IAALMGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-SGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---SGPVWLSELACRGSEGQLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 526)

CAGQRVANSRDGEDPPSILEGDLWPGLSGELSPGSQEPPVTH
APRQAGTPQN--NSRKKSLKPVKQPKSTRAPMLTAGAPRQERLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VSGPHGCSGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGS-----ALAAPGGARF----GPGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

TG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHSGRWGTVCD--DA-WDL
RDATVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPTRPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--AA
DSNRSSSQEAVSR-PSAP------------------------------------------
---------------TGSLSLGTAD-----ILPPPASPT-------VPQETGPE--AGSP
QLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSRCSGRLEVW-HNG---LWGTVCDDSWDLQDSAVVCRELGCGRAR
QQDPAAGRFGWGAGPIWLDDVGCLGTEASLSECPASPWGKH---NCAHNEDVGISCTDTP
GLDSISDPFSWSWIPGLGRDPDAWLPGELTTKPP----AKLTPSVTEKTTTKAPGKNPKG
TKKWVTKNARRLTTQPPVIPTTKHSRVLGTQRPPELTSQTTT-T-LTTEAS---RRTVSE
STARLSTEAPHRMTSHTTATRTPRAPRERTAKTVATPTTQSPREITSEATVEQ-IPLAST
EPS-----T-ETPTQGSPDSSKD---PAPSPTGSTARG----------------------
------------------------------------------------------------
--------------------------------SGHADEDDYPPWTWDPTSGEDLAKLTTT
AGVPGHTLSWGT-TKSPGAPS---PATRRLPDT--GNEDSYEPSWTWDT-PSGGAPP---
EGTPTAGRPGSTLTTATTQSPGRPSSAPRIRGDTGSLRKL-----WPDRRLQR--PTAA-
RTA-PPAASPAPSASPEPPGPPV---T---LDSVPRLIP-EAAS--RRGVTSDPPDTSTP
-----NPDLASQ--MNSDL---------TLTTPGLT-------LSTPEGAVTP--ALIPD
LSPTPPPTLPKE----------------LTSDPSAPSVVTHLSSTSEL-TPE---SDTTP
NLGTAPYANTFPD--------HSKSPDSSINPHPTGTPHSTLTSQPMTTP----------
--------HSATTPPLTRTP-------------------QPTTPPQPTI-----------
-------------------------------------------------------SLQPT
TSIQPTTTPHPTMTPQSTAS-------------------------PPTTTPHPITNPYPA
T------T-----------------PHPTMTLHSTTSTH-----P-SMTADPT--STPMI
-TTKSILTSSGTELFSPTPAPTVKSSLHPWLTST-GSSHLSTSKMSSLAP---FPNSESS
HSRPSPAPSVDTLSTDDFEPPRSQSPKPSPPPPQTPHSASDPTVTS----DLHLSSMALP
LGQPFPDHLTPRPTPGQSPDPLGPCMAPTP-----PVRVMACEP-PALVELVAAVREVGG
QLQRLT------QGPGGPLAGVQAG---AASWV---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
HC------N-NGRDASVGCSDS--------------------------------------
---------------------------------------EIPLRLA

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 642)

NGSSRCAGRVEVLH
DQQWGTVCDDDWDLTDAGV-VCRQLGCGT-----VLSAPGAAQF----GQGSERIWLDDI
NCKGTEAALSECTARPWGDNN---CNHGEDA------SAVC

ENSGT00900000140803_2_Linker_3_4 (642, 758)

SDC----------------
------------------------------------------------------------
-------------RGH-KEPGRFAGSGANSLVW----

PF00530 // ENSGT00900000140803_2_Domain_4 (758, 883)

-VEVLHDQQWGTVCD--DD-WDL
TDAGVVCRQLGCGTVLSAPGAAQF--------GQGSER-------------IWLDDINCK
---G-------TEAALSECTARPWGDNNC---NHGEDASAVCS-----------------
------------------------------------------------------------
---------------------------------------------------------AEI
PLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGPSHCAGRVEVL-HDQ---QWGTVCDDDWDLTDAGVVCRQLGCGTVL
S-APGVAQFGQGSGRIWLDDVNCTGTEAALSECTARPWGDS---NCNHGEDASAVCSALG
LSFVD-NNA---------------------------------------------------
----------------------------GQAP-----------LPPTQP-----------
------------------------------------------------------------
------------L----LV------PTNS--------TPPAEIPLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GPSHCAGRVE
VLHDQQWGTVCDDDWDLTDAGVVCRQLGCGTVLSAP----GVAQFGQGSGRIWLDDVNCT
GTEAALSECTARPWGDS---NCNHGEDASAVCSV--------------------------
------LLTLRF-TGKGAGG------ATVGSAQA-DGAWGHHG-KAWRERKEKEIYCR--
-IQLGA--------ETGPIGPGS-------------------------------------
------------------------------------LD----------QTRSAPGWN---
-NQTSCPLPLSC------LY----------------------------------------
-----------------RP-------------VSH-------------------------
-------------------------PLAVAVI----------------------------
------------------------------------------------------------
-------KHS----------------TV---LVLT--------------------GE---
--------------IPLRLA

PF00530 // ENSGT00900000140803_2_Domain_15 (2001, 2108)

NG----------------------------SSRCAGRVEV
LHGQQWGT---------------------VCDD----DW-----------DLT--DAGV-
-MCRE--L----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLLLELSPSTEEPLVTH
APRPAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSPPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTEPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKNAKRPTTQPPVMPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRRTSE
FTRRPTVEAPQRWTSHTTATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKS-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSVSTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
AGVPGHTLPWRT-TRRPGSSS---PATRRLPDT--GSKDGYKLPWTWDT-PSGGGLA---
EGTPTAGKLGPTLGAGTTRSPGSP-PTPRVHGDTGSPRKP-----WPERRPPR--PAAT-
RTA-PPTPSPGPSASPGPPGPAL---T---SDSSPELTP-HSAL--TSEATSDAPDTSPP
-----TPDPASR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
LSPTPLPTLPKE----------------LTSDPSTPSEVTSLSPTSEQ-VPE---SDTTP
DLDTTPYSSTVSE--------YSRSPDPSPSPHPTTTPDPT------MAP------DRIT
TPNPTVTPHFPTTPHPTTTPQ-------PTTITHSTMIPDPTTTPQPFTTMQP-------
----------------TTIPHPTTT-PHPTTTXXXXXXXXS-------TTPHPTTTPHPT
TTPHPTTTPHPTTTPHPTTTPHPTTTPHPTTTPHPTTTPHPTTTPHPTTTPHPTT--T--
--PDPTTT-----------------PYPTTTPDPTTTPH-----P-TTTPDPS--STPVI
-TTMSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPSLTPPPTHTPHSASDLTVSP----DPLLSPTAHP
LDHPPLDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQERQERQALLLGLTQLVEAARGLGQLSEAV--------------
---------------------------------KRLAEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------RESP--------
-RCL--------A---PFLQPSERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLLLELSPSTEEPLVTH
APRPAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
QDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSPPPAFPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTEPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKNAKRPTTQPPVMPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTSE
FTRRPTTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKS-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSVSTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLQDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
AGVPGHTLPWRT-TRRPGSSS---PATRRLPDT--GSKDGYKLPWTWDT-PSGRGLA---
EGTPTAGKLGPTLGAGTTRSPGSP-PTPRVHGDTGSPRKP-----WPERRPPR--PAAT-
RTA-PPTPSPGPSASPGPPGPAL---T---SDSSPELTP-HSAL--TSEATSDAPDTSPP
-----TPDPASR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
LSPTPLPTLPKE----------------LTSDPSTPSEVTSLSPTSEQ-VPE---SDTTP
DLDTTPYSSTVSE--------YSRSPDPSPSPHPTTTPDPT------MAP------DRIT
TPNPTVTPHFPTTPHPTTTPQ-------PTTITHSTMIPDPTTT----------------
--------------------------PQPFTTM---------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------HLHPQLTFTAPAPHTSTSQIPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPSLTPPPTHTPHSASDLTVSP----DPLLSPTAHP
LDHPPLDPLTLGPTPGQSPGHHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQERQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRLAEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTATPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRGL--------
-ACL--------LAMLVGIQAIERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWY-SGRWGTVCDDGWDLRDA
AVACRVLGCGGALAAPG-GAFFGEG---TGPVWLSELNCRGNEGQLGICPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CVGQRAANSRE--DSMSLLDGDPWLALSGELSPSSEEPPITH
APQPAASSQN--GPRKKNPRPPKQTKSTRAPVLTNGAPHQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGEGPVWMDDV
GCGGGEEALRDCPRSPWGRSN---CDHTEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDG----------------
------------------------------------------------------------
----------------------------------------------------------SP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVGCVGTEASLSECPAASWGKH---NCAHNEDVGVTCTGTP
GLDTISDPFSWSWLPGLGRDQDAWLPGELTTKAS----AGLTSSVPQKP-TKAPGKAPKS
TKKWVTKNAKRPTTQPPGMPTTKRSRVPGTPTSLNPTPR------------------TPE
SPRRLTTEAPHRQSSHTTERLTPRVPWEWTSEPVVSLSTQGPQKVTSEATTTP-TPQTSL
EPS-----G-ENP-EGSLESSQD---PAATPTAGVPV-PAGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGLWGTVCDDSWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSETSLSDCPSGAWGKH---NCDHEEDVVLTCTGYTDDDDYPSWTLDPTSGEDLTKGTTV
AARPGHTLSWAT-ATNTGVHS---PATQSLPDT--DDGGGYEFSWTWDT-PSGRGLS---
KGTPTTTKPGSTVITSTRKSPGHPFPAPRARADTGSPRKA-----KPERRPL---PTSA-
RTA-PTTSPPASSTSPEPSG------SRQTSGSWPQLIP-DSAS--KQEGTSSPPKPSPL
-----TPGLPSP--------------------ASFA-------LSTPDARLLP--TPSPE
LSVSPTPTSPEG----------------LTSDSSVLSEVSSRSPTSEL-TPG---SDTTP
----AP--EITPE--------SSDSSDLPMNPRTPTQPF--------------------T
A-------------------------PHPTTIPQ--------------------------
------------------------------------------------------------
----LNTTSYPTMAPQLTTNPQQPRSPHPTTS----------------------------
-------------------------------PQSPTNTQ-----P-----SST--PAA--
-PTESPPSPGETEFSSPTSQPRVKASLTPELTFE-EAPSTDTSQMQNLEL---LLASKSG
PSRPSPASNMNPLSTDAFKPPRSQT----------LYSASDPMVTP----DLPISSVAHP
SGQPSPDHLTQEPTPNHNPGPFGPCVSPVP-----PVRVMACEP-PALVELVGAVRQVGD
QLQRLT------WVLEQDRQERQVLALGLAQLVEAAQGLGQLSETV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPVPTTITTEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLL-NLMLAIS
TIFVESCLS----------ESPSKVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGAHRCEGRVEVER-NGQWGTVCDDGWDWNDL
VVVCRELSCGAAKRTQS-GASYRPPAPEDQKVLIQDVNCTGMEDTLSQCEQN---EDVY-
NC------P-HSEDAGARCVNP--------------------------------------
---------------------------------------DS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
DVRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGRCQGRVELL-HQE---QWSTVCKAGWNLRAAKVVCRQLGCGRAL
LTHRCCNKMTQGQGPIWMRQVSCFGQEVNLQDCPLRPLE-N---NCTHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFQLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDNPCAGRLE
VLHKGTWGSVCDDSWGEEEDQVVCKQLGCGKPL--SLSFKAQKSYRPGAGHIWLDDVVCS
GKEKSLESCQHRLWGYH---DCTHKEDVAVMCSEFDV-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ASPPGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVRQ-NGQWGTVCDDGWDIKDV
AVVCRELGCGAANGTPS-GILYEPPAENEQKVFIQEVSCTGTEDTLAQCEQ----EEAY-
NC------L-HNEDAGALCENP--------------------------------------
---------------------------------------ESPL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---RWYSVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKPAQGQRSIWLSQMSCSGREATLQDCPSGPWGKS---TCIHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLDCGKSL--SPSFKDRKSYGPGVGRIWLDNVRCL
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------MALGRHL--SL------------RG--
-LCV-------LLLGTVVGGQDLEVRLN

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 440)

DGTHRCEGRVEVRL-QGEWGTVNDHNWSMEEA
AVACRQLGCGGAVDAPK-GAKFGLG---VGPIWFDYIYCKGHESAITECSYPTVKDHRPE
GH------S-HDKDAGAVC

ENSGT00900000140803_2_Linker_2_3 (440, 527)

SAL--------------------------------------
-----------------------------------------EVRLK

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 642)

DGAHRCEGRVEVKH
QGEWGTVDDLNWSMEEAAV-VCRQLGCGG-----ATDAPKRAHF----GPGIGPIWFRYI
YCKGPESAITECSYPPVKDHRPEGNSHDKDV------GAVC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

SD-----------------
------------------------------------------------------------
------------------LELRLK

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 1018)

DGAHHCEGR-----LEVKHQGEWGTVND--LN-WSI
EEAAVVCRQLKCGAAVDAPKGARF--------GPGIGP-------------IWFDYIYCK
---G-------PESAITECSYPTVKDHRPEGHSHDKDAGAVC------------------
------------------------------------------------------------
---------------------------------------------------------

ENSGT00900000140803_2_Linker_4_6 (1018, 1033)

SVL
EVRL--K-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGAHHCEGRVEVK-YQG---EWGTVNDHNWSLEAAAVVCRQLECGAAI
N-ASREAHFGPGIGPIWFQYIYCNGTESVLRECSYPTIKDHLAESLSHDGDAGAVC

ENSGT00900000140803_2_Linker_6_8 (1137, 1177)

SDL-
-------EVR------------------------LK

PF00530 // ENSGT00900000140803_2_Domain_8 (1177, 1361)

DGA-HRCEGR---------VEVKH
LGEWGTVNDHNWRLEE--AQVVCRQLGCGAAT-----------DAFRGAHFGPGIGPIWF
RYTY----------------------------------CHGLESVLT-------------
------ACTYPVPKDYHPEGLSHDQDAG---------AVC

ENSGT00900000140803_2_Linker_8_9 (1361, 1368)

SNLELRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

TN-GDHSCEGRVE
VKHQGEWGTVNDLNWNMEEAHVVCRQLRCGAAVGAP----KASKFGPGIGPIWFHYIYCK
EQESVITECSYPPLKDHRTEGYSHNKDAGAIC

ENSGT00900000140803_2_Linker_9_12 (1473, 1518)

SA--------------------------
----------RE-VRLK

PF00530 // ENSGT00900000140803_2_Domain_12 (1518, 1976)

DGAH---HCEGRVEVKH-QGEWGTVNDHNWS-LEAAAVVCR--
-E-LEC--------GAAINASRGA------------------------------------
------------------------------------HF----------GPGIGPIWF---
-QYIYCNGTESS------LMECS--------YPPLKNHLPEGLSHDGDAGAVC-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

ENSGT00900000140803_2_Linker_12_15 (1976, 2001)

SA---
--------------LEVRLK

PF00530 // ENSGT00900000140803_2_Domain_15 (2001, 2237)

DG----------------------------AHSCEGRVEV
KHQGEWGT---------------------VNDH----NW-----------NIE--GAQV-
-VCRQ--LGCGAAI--------------------------------------------DA
PGGAYFGPGIGPIWFHSINCQGKESL------------LTVCSYPSLKD--------YRP
E---GLSHDQDAGAVC

ENSGT00900000140803_2_Linker_15_16 (2237, 2273)

S----------------------------ALELRLR

PF00530 // ENSGT00900000140803_2_Domain_16 (2273, 2400)

DGAHSCEG
RVEVK--HQGEWGTVNDYNW----------NIEEARVVCRQLRCGP-------AVDAPQR
SKFGPGTGPI-------WFH--YIYCKGQESAINECSYPVVIDHHPEGHSHNKDAGVVCS
V-----------------------------------------------------------
------------------------------------------------------------
------------------------------------LEVRLK

PF00530 // ENSGT00900000140803_2_Domain_18 (2563, 2662)

DGAHHCEGRVEVKHQGEW
GTVNDDTWSMEEAQVVCRQLKCGAATDAPRGAYFGSGIGPIWFQYVYCNGTEAMLTQCSY
PPLKDHHPEGLSHDKDAGAVC

ENSGT00900000140803_2_Linker_18_19 (2662, 2703)

SAL---------------------------------ELR
LK

PF00530 // ENSGT00900000140803_2_Domain_19 (2703, 2809)

DGAHSC-----EGRV--EVKHQGEWGTVNDQNWSLEEAAVVCRQLGCGVAINASRGVH
FGPGIGPIWFQYIYCKGTESVLTTCTYPVLKDYRPEGLSHDQDAGAVC

ENSGT00900000140803_2_Linker_19_20 (2809, 2833)

SA----------
------LEVRLN

PF00530 // ENSGT00900000140803_2_Domain_20 (2833, 2933)

DGTHRCEGRVEVRLQGEWGTVNDH-NWSMEEAAVACRQLGCGGAVDAP
KGAKFGPGVGPIWFDYIYCKGQESAITRCSYPTVKDHRPEGHSHDKDAGAVCSGKCCLVQ
KGIPSRRSL-------------SLIPRITMRIWITAFRTFLGEDSSDPVTP---------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------ELRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGSSPCAGRVEVKL-QGEWGSVADGDWDMEDA
EVVCRQLGCGSASKANYARDTFGIG---NGLVSLVLVDCRGDEATLWDCEIR---GWGPY
NG------SDHFLDTAVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

Q----------------------------------------
----------------------------------------GFSRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VGGDGACAGRLEVRR
GRAWVGVCADQVDMKAAQV-VCRELGCGE-----GLAIPGSARF----GRGSGSFWDGDF
QCNGTESLLSACARRL-----PLSQACAGPA------SVIC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

SEG----------------
------------------------------------------------------------
-------------P---EVRVRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 883)

GSSGRCAGR-----VEVYSGGSWSSVCQ--EG-WEL
QDAAVVCRELGCGTALEAPSRARF--------GEGTGR-------------IWLQLFFCL
---G-------GENALEECPHLGWGLHFC---GHDRDVGVTCT-----------------
------------------------------------------------------------
---------------------------------------------------------DAV
ELRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-GGSSPCAGRVEVK-LQG---QWGSVGDDDWDMEDAEVVCRQLGCGSAS
GAYSAHDTFGQGNGLISLARVDCGGYEATLWDCEIRGWGPYK--FFNHYWDTAVVC

ENSGT00900000140803_2_Linker_6_8 (1137, 1176)

QG--
-------LSR------------------------L

PF00530 // ENSGT00900000140803_2_Domain_8 (1176, 1347)

VGGD-GACAGR---------LEVRR
GRAWVGVCEDQVDMKA--AQVVCRELGCGEAL-----------AIPGSARFGRGSGSLWD
GGFQ----------------------------------CNGTESLLS-------------
------ECARRLPLSQACAGPASVIC

ENSGT00900000140803_2_Linker_8_9 (1347, 1370)

S-------------AYTGFRLGN

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-SSSGCSGRVE
VAVRGTWGSVCASEWDLADAHVLCRHLGCGRASSVP----PGGSFGSGEGTLRPDAFGCH
GSERHPGECPVAVLGKP---PCVPGNAAAVNCSGM-------------------------
---------DDQ-LEEMGDVS---------------------------------------
------------------------------------------------------------
--------------------------------------------------GMGPA-----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------LNS-----------------------
------------------------------------------------------------
-------------------------SVEEMAITCS--------------------GS---
--------------RQVRLA

PF00530 // ENSGT00900000140803_2_Domain_15 (2001, 2202)

GS----------------------------SGRCAGRVEV
YSGGSWSS---------------------VCQE----GW-----------ELQ--DAAV-
-VCRE--LGCGTAL--------------------------------------------EA
PSRARFGAGTGPLWPYVPDCSGSEES------------LWEC------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------GRPSHCLL--------
-PFF--------AAALVGIQAVDRLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWY-GSRWGTVCDDGWDLQDA
AVACRELGCGGALAAPG-GAFFGEG---TGPVWLSELACQGLEERLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 538)

CTGQRAADSQH--DSTSPLDGEP--------RPGSEEPPVTH
GEPP---------------------------------------------------DR

PF00530 // ENSGT00900000140803_2_Domain_3 (538, 641)

VWH
GGRWGSVCDDGWDLQDAAV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCAGAEQALRDCPRSPWGRSN---CDHREDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 765)

CTG-----------------
------------------------------------------------------------
----------------RR---------------------GGGPG

PF00530 // ENSGT00900000140803_2_Domain_4 (765, 882)

GRWGSVCD--DA-WDL
QDAAVACRELGCGGALAAPGAAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YATPTRP--VV
DSNSSG------------------------------------------------------
---------------TVSQAPRMPG-----SLPPAASPT-------APQEPGPD--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDLRDSAVVCRELGCRGPR
QPDPAVGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVMCTGTP
GLDTISDPFSWSWLPGLGRDRDAWLPGELATKPS----ASLTSIVPEKTTTKAPRKTPKS
TKKWVTKHAKRPTAQPPRMPTTKHSRGLGTQSPPELTSQTTTLT--------------TE
LLKRLLTEAPHRWTSHTTSKPTPQAPWTWPSGTMTTLSPQGPQEMTSETTIEK-IRQASL
EPS-----A-ETPAF--------------SPTGL---PPPGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDSWDLRDATVVCWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSETSLSDCPSGGWGKH---NCDHEEDVGFTCTGYTDDDDYPPWTWDPTSGEDLAKGATM
APGPGRALPWSS-TRHPAISS---PATRLLSVT--GDQEGYKPSGTWDT-PWGRGSA---
KRTPT---TAPTLSSGTSRPPGHPSLAPRAHGDTGEQVAG--------------------
------IAI--------------------------------------------RSSRL-P
GSGI--------------------------------------------------------
--------------------------------SAPQGE-------------------GTP
GPNTAPYWGTAVG--------TSGSPEPSTSPHPTATKSSP-------------------
------------------------------------------------------------
------------------------------------TTPYPTITPNPTTTANPTTSPHYT
TTLQPMATPLPASTLPTTTIPL--------------------------------------
----PATT-----------------PHPTATPHPATTTR-----P-ARTADPS--STPMV
-TTKSLPTSLGPESPSS-------------------------TTMQSPVP---SPASEAS
PSRAPLTSSRGPLSTEDFRPPRSQNPTLTPGPASEPILPSDP-----------------H
SDQLPHDHPPLGPTPGQTLGPLGPCACPAA-----PVRVRACEP-PALVELVAAVRDVGG
QLQRLA------TVLEQDWQERQALGLGLAQL-----GLGQLGETV--------------
---------------------------------RRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WAPSTPVSTSTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MAPLF-NLMLAIL
SIFVGSCFS----------ESPTKVQL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGAHRCEGRVEVEH-NGQWGTVCDDGWDRRDV
AVVCRELNCGAVIQTPR-GASYQPPAS-EQRVLIQGVDCNGTEDTLAQCELN---YDVF-
DC------S-HEEDAGAQCENP--------------------------------------
---------------------------------------DSDL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LFI----------------
------------------------------------------------------------
----------------------------------------------------------PE
DVRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

DGPGHCQGRVEVL-HQS---QWSTVCKAGWNLQVSKVVCRQLGCGRAL
LTYGSCNKNTQGKGPIWMGKMSCSGQEANLRSCLLSRLE-N---NCTHGEDTWMECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1472)

VG-GDTPCSGRLE
VLHKGSWGSVCDDNWGEKEDQVVCKQLGCGKSL--HPSPKTRKIYGPGAGRIWLDDVNCS
GKEQSLEFCRHRLWGYH---DCTHKEDVEVICTDFDV-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLL-NLMLAIS
TVFIGSCLS----------ESPSKVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGAHRCEGRVEVER-NGQWGTVCDDGWDLNDV
AVVCRELSCGAAIKARS-GSSYKPPAPE-QKVLIRDFNCKGMEDTLSQCEQD---GHVY-
NC------P-HTEDAGAQCENP--------------------------------------
---------------------------------------DIDS-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFI----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGRCQGRVEVL-HQL---EWSSVCKAGWNLQASKVACRQLGCGRAL
LTHACCNKTTQGKGPIWASQMSCAGQEANLRDCPFRSLE-K---NCTHDEDAWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDNPCSGRLE
VLHQGTWGSVCDDGWGEKEDQVVCKQLGCGKPL--VPSSKARKSYGPGAGRVWLDDVVCS
GEEQSLESCRHRFWGYH---DCTHKEDVAVICSDFDG-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILT--
-VCIRPGFL----------ESPSRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEVEQ-KGQWGTVCDDGWDKNEV
AVLCRELGCGDANGTPS-GYLFEPPAEKNQEVLLQEIRCTGTEDTLAQCEQ----EAAY-
DC------S-HDEDAGASCENP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGHVEVK-HQD---QWYSVCQAGWSLRAAKVVCRQLGCGRAL
LIQKHCRKPAQGQRPIWLSQMSCSGREATLQDCPSGPWGSN---SCNHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AFALRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDGWGEKEDQVVCKQMGCGQSL--SPSFKDRKSHGPGAGRIWLDDVRCS
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSE--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MRVLACLLERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVCTGTSGWGLAPPVFLRPR--
------LPL---------------------------------------------------
---------APPVTKNACLRLEPSPGMQEALAA-----LCHWAGHGRDPLGE--PF----
-SVANLCSFPVLKGAGGKEGGRLV--------TWGHGGRLRQGGDIHGDLCVQLRGLRKD
DAGGGGAS-------SRM--------EGV---CGWQSLTPCSTGMPLG-YVPPTAP---T
DSNNSTPREAASR-PPAT------------------------------------------
---------------MMSQAPGTAG-----VSPPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGSP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKNANRPTAQPPVTPTTKHSRAQ---SPPDLTSQTTT--ALTTEAS---RRPTSE
FTRRPTTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTTQGPQEMTSEAAIER-VPQASL
EPS-----A-EIP-EGSLESPKD---PAPSPSASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
ARVPGHSLPWGT-TRRPGSSS---PATRRLPDT--GGKDGYKLPWTWDT-PSGRGLA---
EGTPTAGKLGPTLRAGATRSPGSP-PTPRVHGDTGETRGW------GEGTGRY-------
----------------------LSWGK---------------------ETDS--------
------------------------------------------------------------
-------RLPSG----------------------------------TL-TPE--------
---------------------RLS-----RTQWL--------------------------
------T------------PV------------------------IPTL-----------
------------------------------------------------------------
----------------------------------WEA-----------------------
------------------------------------------------------------
----QAGGSRGQEIE-TILANTVKPRL----YYKY-------------------------
------------------K-----------------------------------------
-------K----------------LSRRRG-----GRLVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRLAEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSVPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------A----------ESPPKVRLI

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

GGPHRCEGRVELEL-NGQWGTVCDDGWDLTDV
AVVCRELNCGAANKTLS-GTLYKPAAPENQRVLIQDVNCNGMEDALSECEQN---EDVF-
NC------P-HSEDAGARCED---------------------------------------
------------------------------------------A-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFS----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGRGHCQGRVELL-HQV---QWSSVCKAGWNLRASKVVCRQLGCGRAL
QTHRGCSKMAQGKGHIWMGQMSCSGQEANLQDCPFKPLQ-N---HCTHSEDTWIECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELRLAG

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-GDNPCSGRLE
VLHKGSWGSVCDDGWGEKEDQVVCRQLRCGKPL--S---EARRSYGPGVGRIWLDDVVCT
GEEPSLESCLHRLWGYN---DCTHKEDVAVTCSETTPDFDV-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRAL--------
-ACL--------LAMLVGIQAIERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-SGRWGTVCDDGWDLRDA
EVACRVLGCGGALAAPG-GAFFGEG---TGPVWLSELNCRGNEGQLGICPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CVGQRAANSRE--DSMSLLDGDPWLALSGELSPSSEEPPITH
APQPAASSQN--GPRKKNPRPPKQTKSTRAPVLTNGAPHQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGEGPVWMDDV
GCGGGEEALRDCPRSPWGRSN---CDHTEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRIRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACKELGCGGALAAPGGAFF--------GEGTGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-AVQPTVP--AV
DSNSTAH-----R-LLST------------------------------------------
---------------SVGQMPGPAG-----PWPPSASPT-------APPEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDMRDSAVVCRELGCGRPR
QPDPAAGRFGWGAGPIWLDDVGCMGTEASLSECPAASWGKH---NCAHNEDVGVTCTGTP
GLDTISDPFSWSWLPGLGRDQDAWLPGELTTKPS----ASLTSSVPQKP-TKVPGKAPKS
TKKWVTKNAKRPTTQPPGMPTTKHSRAPGTPTSLHPTAR------------------TSE
LPKRLTTEAPHRQTSHTTVRLTPRVPWEWTSEPVVSQSTQGPQEVTSEATTTE-NPQTSL
EPS-----G-ENT-EGSLESSQD---PAATPTAGVPV-PSGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGLWGTVCDDSWDIRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEMSLSDCPSGAWGKH---NCDHEEDVVLTCTGYTGDDDYPSWTWDPTSGEDLTKGTTV
AARPGHTLSWAT-TTNTKVLS---PATQSLPDT--DDQGGYEFSWTWDT-PSGRSVF---
KGTPTTTKPGSTVTTSTSKSPGHPFPAPRARADTGSPRKP-----TPERRPL---PTSA-
TT-----SSPASSSSPEPSGSRQTSGSRQTSGSRPQLIP-DS----KQEGTSSSPKPSSL
-----TPGLPSP--------------------ATFA-------LSTPNTSLLP--TRSPE
LSGSPTPTSPEGLT--------SASPEGLTSASSMLSEVSRLSPTSEL-TPG---PDTTP
----AP--EIIPE--------SFDSSDLPMNTRTPTQPF--------------------T
A-------------------------SHPTRIPQ--------------------------
------------------------------------------------------------
----LNTTSYPTIAPQPTTNPQQPRNPHPATS----------------------------
-------------------------------PQPPTNTH-----P-----SST--P-A-T
-PTESLPSSRKTEFSSPT-----KPRLNSELIFE-EAPPTDASQTQNLEL---FLASESG
PSSPSPASNLDPLPTDAFKPPRSQT----------LHSAS--------------------
------DHLTQWPTPNHNPDPFGPCVSPVP-----PVRVMACEP-PALVELVGAVREVGD
QLQRLT------WILEQDRQERQVLALGLAQLVEAAQGLGQLSEAV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPVPMTTTTEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------L---------ERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLSVELSPSTEEPLVTH
VPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEALLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKYTKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTAE
FTRRPTTEARRRWTSHTTATLTPQAPRERTTKTIAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSAGTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
ARVPGQTLPWGT-TRRMGISS---PATSRLPDT--GGRDGYKLPWTWDT-PSGRGLA---
EGTPTAGKLGPTLGAGTTRSPGSP-PTPRVHGDTGSPRKP-----WPERRPPR--PAAT-
RTA-PPTPSPGPSASPGPPGPAL---T---SDCSPELTP-HPAL--TPEATSDPPDTSPP
-----TPDPTSR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PLPTPLPTLPKE----------------LTSDPSTPSEVTSLSPTSEQ-IPE---SDTTP
DLDTTPYSSTVSE--------YSRSPDPSPSPHPTTIPDPT------MTP------DHNT
TPNPTVTPHFPTTTHSTTTPQ-------PTTITHSTMIPDPTTTPQPFTTMQPTTTPHPT
TPHPTTTPHPTTTTHSTMIPDPTTT-PQPFTTMQPTTTPHP-------TTPHPTTTPHPT
TTTHSTMIPDPTTTPQPFTTMQPTMIPHPTTTPYPTTTSHPTTTPHPI------------
-----------------------------TTPDPTTTPH-----P-TTTPDPS--STPII
-TTKSLPTSLGTELSFPTLAPTVKPSLHPQLTFTAPAPHTSTSQMPTLEP---SPALESS
PSRSSTATSMDPLSTEEFKPPRSQSPNLTPPPTHTPHSASDLTMSP----DPHLSPIAHP
LDHPPLDPLTLGPTPDQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAAQGLGQLGEAV--------------
---------------------------------KRLAEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVEQ-KGQWGTVCDDGWDIKDV
AVVCRELGCGAASGTPS-GILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQ----EEVY-
DC------S-HDEDAGASCENP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
GVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---QWYTVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKN---TCNHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDNLCCGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFRNRKCYGPGVGRIWLDNVRCS
GEEQSLEQCQHRFWGFH---DCTHQEDVAVFCSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---TGLVWLSELACRGSEGQLGFCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 526)

CAGQRVANSRD--NPASTLDGDSWLGLSGELSLTSEEPPVTP
APHPAGSPQN--SSRKKTPRPPKQAKSTRAPLLTSGSPRQERLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VSGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

TG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHSGRWGSVCD--DA-WDL
RDAAVACRELGCGRALAAPGGAFF--------GEGSGP-------------IILDDLRCR
---G-------NETALRFCPSRTWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--AV
DSNTSTSRQAASM-PLSP------------------------------------------
---------------TVSQALGTAG-----ISPPPASPT-------APWEPGPE--VGSP
QLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSRCSGRLEVW-HDG---RWGTVCDDSWDMRDSAVVCWELGCGGPR
QPDPAAGRFGWGAGPIWLDDVGCVGTESSLSDCPAALWGKH---NCAHNEDVGVTCTGPP
GLDSVSDPFSWSWIPGLGRDQDAWLPGEVVTKPP----ASLTSSVPEKTTTKVPGKMPKS
TKKWVTKNTKRPTTQPPVMPTTKHAGGLGTQNPPALTSWTTT-T-LT-----------AE
FTTRLTTETPPRQISHRTAILTSQSPQERNSKTTAILTAQGPQEMTSEATIRK-IPQASL
EPS-----A-ELPAEGSPESPKE---PSLSPTDSTTE-KSGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSETSLTNCPSRPWGKH---NCDHEEDVGLTCTGYSDEDDYPPWTWDPSSGEDLAKGTTV
EGVPGHALSWGT-TRRPAVSS---LSTWRLPDT--GDKDGYKPPWMWDK-SMGRGLV---
KGFPTTGKPL-THATGTTRSQGSPLPAPRFYGDTGSRRKQ-----WPERRLLR--PTEV-
RTA-PLTPSPAPSASMELPSPPL---T---SDSQPQLIP-NLVS--RPEATSNPPDTSPP
-----TPDLASW--TNPDL---------VFTSPHLI-------LSTPDSSVIP--MPTPE
LSPPLPPTLPVG----------------LTSDSSVL---------SEM-TPE---SDTTP
DLDTTPYPKTVLE--------SSSSPNLSTSPYHTTTPHPTITLHPATTP------Q---
---------PPTTPYPVTTPQ-------LITT------------PQPMI-----------
------------------------------------------------------------
-T----------------------------------------------------------
--TEPTMT-----------------PELTTTPQPTTAPQ-----P-TTDPHLT--SAPIF
-TSKFLPTSLGTELSSLTSTPTSKPSLPPELSFTTPATHTSTSQMPTLEP---SSTLESN
TSSFSTAQSLEPLSTEDFESSGSQSS----------------------------------
--KPPPDHLNLGLPTGQSSGPVGPCVVPTP-----PVRVMACEP-PALMELVAAVRDVGG
QLQRLT------HVLEQDRQERQALGLGLTQLVEAAQGLGQLGEVI--------------
---------------------------------KRLAEVT--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPVPTTTTLEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---TGPVWLSELACRGSERQLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVADSRDREDSPSILDRDPWPGLSGELSPSSEEPPVTP
APRPAGTPQN--TSRRKSPRPSKQAKSTRAPLLTAGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCSGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--AV
DSNSSRPREAASR-PPPP------------------------------------------
---------------AASQAPGTAG-----LPPPPASPT-------APREPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDLRDSAVVCRELGCGSPR
LSDPAAGRFGWGAGPIWLDDVRCMGTEASLADCPAAPWGKH---NCAHNEDVGVTCTGMP
GLDSISDPFSWSWIPGLGRDPGVWLPGELATKPS----ARLTPSVPEKTTTKAPGKMPKS
TKKWGTKTTKKPTTQPPEMPTTKHSRAPGTQGPPELTSRTTA-TTLPPEAS---RRPTSA
PTT--------RLTSHAPVTRTPRAPRERSSKTMAAPTKQEPGEMTSEAP---------V
EPS-----A-EILGEGSPESSKE---PA-------TG-GSGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDGWDLRDSTVVCWELGCGRVRPRV----GKTHYGPGTGPIWLDDVGCK
GSEASLSDCPSRGWGQH---NCDHEEDVGLTCTGYSDEEDYPPWTWDPTSGEDVAKGTTA
AGMPGRSPSWGT-TRRPGTPAVAATATRRLPGT--GDKDGYALSWTWDT-PLGGTLA---
KGTPTEGLPGPPGTPGTTRSPGHPSPAPRACGDTGSARKP-----LPERRLLR--PTAA-
RTA-PPVPSPAPSTSPEPPGPLP---T---SDSPPQLIP-TAAS--TPEVTSDPPDTLPP
-----SPDPASS--MNSHR---------ALTTPGLD-------FSTHAATVVP--ALTPG
LS----PSMPKE----------------LTSDPTAPAVVTRLSSTSERTQPE---SDTDP
GWDTTPYPSTVPE--------LSSSPGPPTSPHPTVTTS-----HPAT--TL----HPTT
TFHPTATPQQTFTPYLTTTPR-------PTTTAQPTTTPRPTTTAQPT------------
------------------------------------------TTPRPTTTAQPTTTPRPT
TTAQPTTTPRPTTTAQP------TTTPRPTTTAQPTTTPRPTTTAQPTMTPYPVTT----
-------------------------------SYPATTPH-----LTTTTPNPT--TTPLI
-TSQSLLTSLGTEPPSSSPAPAVEPTF-------AGAPHPSGSQTWSPEP---SPVPS--
-----------TPSTENLTPPGSQSPKLTSPSTQDPYSVPDPRVTP----DLHLPHMAHP
LDQPPPDRLTPGPTPVQSPGPFGPCEAPAP-----PVRVMACEP-PALVELVAAVRDVSG
QLQRLT------QALERDQQERQALGLGLTQLVEAAQGLGQLGEVV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTSAPITTTLEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------

PF00530 // ENSGT00900000140803_2_Domain_3 (538, 642)

VWH
GGRWGTVCDDGWD-RDAAV-ACRELGCGG-----PLAAPGGSRF----GPGAGPVWMDDV
GCGGGEKALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

TG-----------------
------------------------------------------------------------
----------------PAPRLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

ADGPHGCAGR-----LEVWHSGRWGTVCD--DG-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------IMLDDLRCR
---G-------NETNLRFCPARPWGQHDC---HHREDAGAVCDGMPLG-HMPPTAP--MV
DSSNXXXXXXXXXXXXXX------------------------------------------
---------------XXXXXXX---------XXXXXXXX-------XXXXXXXXXXXXXS
HLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSRCSGRLEVW-HGG---RWGTVCDDSWDLRDSAVVCRELGCGGPQ
QLDPTVGRFGWGAGPIWLDDVSCVGTEVVLTDCPAAPWGKH---NCAHNEDVGVTCSGTP
GLDTISDPFSWSWLPGLGREQDAWP-GGLVTKPTASXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXX-----X-XXX-XXXXXXXXX------X--XX-XX-XXXXXXXXXXX-XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXX-XXXXXXXXXXXXX
XXXXXXXXXX---XXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-XXXXXXXX---XXXXXXXXX--XXXXXXXXXXXXXX-XXXXXXX---
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSPRKP------------------GF
KHWLLPTPSPAPSASPGTLLTSA------TPD-----------PEPTAEATSDPSATSPP
TTEPAS----------------------------LP-------WSTSASSATLGGTAEPS
PTHTSLPTLSTE----------------LTSDRSAQGDVSSLAPTSEL-SPE---LDTTP
DISSTSYPRIDP------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ESPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEVEQ-KGQWGTVCDDDWDIKDV
AVVCWELGCGAAYGTPS-GILYEPPAEKEQKVLIQSVNCTGTEDTLAQCEQ----EEVY-
DC------S-HDEDAGASCENP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
GVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGHVEVK-HQN---QWYIVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKHGYGQKPIWLSQMSCSGRETTLQDCPSGPWGKN---TCNHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFKDRKSYGPGVGRIWLDNVRCS
GEEQSLEQCQHRFWGFH---DCTHQEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------LRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---VGPVWLSELACRGSEGQLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 526)

CADGQVPALLHRD-------------------------PIFC
SP-------------------------------DPGTLPHSRLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VSGPHGCSGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

TGMKTASTCVPTLHVET--
------SSW---------------------------------------------------
---------E--V--SPAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDASVS-------------
------------------------------------------------------------
--------------------------------SPKSAPS-------VVWPTGQETTAIGK
ILRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1136)

-AGPSRCSGRLEVW-HSG---RWGTVCDDSWDLRDSAVVCRELGCGGAR
QPDPAAGRFGWGAGPIWLDDVRCVGTEASLFQCPAAPWGKH---NCAHNEDVGVTCA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-TLILA--
-ICAGPGLS----------ETPPRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEVER-SGQWGTVCDDGWGLEDV
AVVCRELGCGAAKKSPS-GTVYGPLAEKHQSIFTQNVNCNGMEDTLAQCEQD---EEVY-
GC------D-HNEDAGASCDNP--------------------------------------
---------------------------------------ESSSSPEPES-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------S---FSTGPEIPFSLV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

GGPGRCAGRVEVQ-HEG---RWSTVCKTGWSLQAAKVLCRQLGCGRAL
LVLRQCNNTIQGQGSIWMSMMKCSGQEATIQDCNSGPLKKN---SCTHLDDTWVKCED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AFELRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GGSICSGRLE
VLHKNKWGTVCDDSWGEQEDQVVCKQLGCGKPL--ISHS--GKRYGPGFGRIWLDDVRCS
GKEQSLDQCKHRFWGYH---DCDHTEDVSVTCSE--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MRVLACLLERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHTEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTGMRDGWGAQITPSP----
---------------------LQFSGPSSSLPPGS-----------------SCLSAHSL
EIWEILVTLSPVLYPGPAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------IVLDDLRCR
---G-------NETALRFCPSRSWGQHDC---HHREDAGAVCDGMPLG-DVQPTAP--TV
DSNTSAPRLL------ST------------------------------------------
---------------SVNQTPGPVG------SLPSASPT-------DPPEPGPK--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDGWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVGCVGTEASLSECPAASWGKH---NCAHNEDVGVTCTGTP
GLDTISDPFSWSWLPGLGRDQDAWLPGELATKPS----ADLTSSVLEKT-TKAPGKAPKS
TKKWVTKNAKRPTTPPPGMPTTRRSRVPGTPSTLNITPRT------------------SK
LPKRLTTEAPHRQMSHTPVKLTPRVPWEWTSETVTSLYTQDPQEVTSEATITQ-TPQASL
EPS-----G-EMESS------RY---PAPTPSAGVPT-PSGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1452)

-GPNRCAGRLE
VWHAGQWGTVCDDSWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSETSLSDCPSGTGRRH---MLP------SLSPGYTGDDDYPSWTWDPTSGEDLTKGTTT
AARPGRTLSWAATTRNPEVPS---SGTQRRPDT--DGQGGYEVSWTWDT-PSRRGLS---
RGTPTTTKPRPTVTSATGKSPGHPFPAPRARAGTGERTTG--------------------
-----------------------------------------------------PPQTSPP
-----TPGLSS------------------LTASDST-------LSTSDASLLP--TGIPQ
HS--------QR----------------LTSDSSTLPEGTRFN--------------TTP
GLGA--TPKIVPE--------SSDFSGIPMSPRTPTQPST--------------------
------VPH-------------------PTPATHPTTTPHPTTTPQH-------------
------------------------------------------------------------
------TTSYPTMTPEHTTDPQLPKALHPT------------------------------
-----------------------------TTPQPP------------TNPHTS--LTAAT
-PTKSLPSSPETGFPSLTLEPRVKPSLHPELTFE-EAPPTSTSGKQNLEP---SPASESD
PSRHSPAPSMDPQSTEVFKPPRSQSPKLTSPPLQTSHSPPDPTVTS----DLHLSSMAHP
LDQPP------RPSPNHNPEALGPCLSPVP-----PVRVMACEP-PALVELVAAVREVGD
QLQRLT------RVLEQDRQERQVLGLGLVRLVEAAQGLGQLSETL--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPVPTTTTTE---EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------SPSRVRV

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGDHRCEGRVEVQQ-DGKWGTVCDDGWDKNDA
AVVCRELGCGAVKRAIS-GTSFGPLTQEDQKIFIQEFKCSGMEESLSQCERE----DFF-
DC------T-HEEDAGVVCGF---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------PQ
TVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPKPCQGRVEVK-HQG---EWGSVCKASWSFAAAKVVCRQLGCGRAI
LTRKCCNKATQGQGPIWLRKASCSGKEISLQDCPSGVWEKS---NCTHDDDMWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELQL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDDRCSGRLE
VLHKGEWGTVCDDGWGEEADQVVCRQLSCGDPL--SPSAKFRRRFGPGVGRIWLDDVACS
GKERSLEQCPHRFWGQH---DCSHTEDVAVVCAGQTPDC---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLV-FLLLA--
-FFTGPAQF----------ESSSTVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEVQQ-NGEWGTVCDDGWGMEDV
AVVCRELNCGEAKWTPS-GTLYTPSTDKDQKVFLQEVICQGHELNLSQCDQV----EVF-
DC------T-HDEDAGAQ

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CEKP--------------------------------------
---------------------------------------SLTVRLA

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 642)

GGPHRCEGRVEVQQ
NGEWHTMCHAGWGMEEAAV-VCRELNCGE-----AKGTPRGTAYEPSTGT-DQKVLMQEV
ICQGHELNLTACEPVD--IFD---CFHNEGA------GVQC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

EK-----------------
------------------------------------------------------------
----------------PSLTVRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 883)

GGPHRCEGR-----VEVQQNGEWHTMCH--AG-WGM
EEAAVVCRELNCGEAKGTPRGTAYEPS-----TGTDQK-------------VLMQEVICQ
---G-------HELNLTACEPVD--IFDC---FHNEGAGVQCEM----------------
------------------------------------------------------------
----------------------------------------------------------LE
NVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-GGPRRCKGRVEVK-HQG---KWGTVCKAGWNLSAVKVVCRQLGCGKAL
LTKRCCS-TTQGQGPIWLSEVSCSGRELSLQRCSSGILGKN---NCTHDDDMCVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDTNCSGRLE
VLHKGEWGSVCDDGWGEEEDRTVCKQLGCGESL--FPSAKI-QKFGRGVGRIWLDDVRCS
GKEKSLEQCQHRFWGHH---DCNHKEDVAVICSEP-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---TTCLFV----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGLHRCEGRVEVKQ-NGQWGTVCDDGWDIKDV
AVVCRELGCGAANGTPS-GILYEPPAENEQKVFIQGVSCTGTEDTLAQCEQ----EEAY-
NC------L-HNEDAGALCENP--------------------------------------
---------------------------------------ESPL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQK---QWYSVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKPAQGQRSIWLSQMSCSGREATLQDCPSGPWGKS---TCIHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFKDRKSYGPGVGRIWLDNVHCS
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALLGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DPTSPLDGAPWPGLSVELSPSTEEPPVTH
VPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGMGRDRDAWLPGELATKPS----ASVTAGVLEKTTTKAPGKMPKS
TKKWVTKYAKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTAE
FTRRPTTEAPRRWTSHTTATLTPQAPRERTTKTTAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPASPKD---PAPSPSAGTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
AGVPGHTLPWGT-TRRTGISS---PATKRLPDT--GGRDGYKLPWTWDT-PSGRGLA---
EGTPTAGKLGPTLGAGTTRSPGSP-PSPRVHGDTGFPRKP-----WPERRPPR--PAAT-
RTA-PPTPSPGPSASPGPPGPVL---T---SDCSPELTP-HPAL--TPEATSDPPDTSPP
-----TPDPTSR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PSPTPLPTLPKE----------------LTSDPSTPSEVTSLSPTSEQ-IPE---SDTTP
DLDTTPYSSTVSE--------YSRSPDPSPSPHPTTIPDPT------MTP------DHTT
TPNPTVTPHFPTTTHPTTTPQ-------PTTITHSTMIPDPTTT----------------
--------------------------PQPFTTMQPTTTPHP-------TTPYXXXX----
--------------XXXXTTMQPTMIPHPTTTPHPTTTPHPITTP------DPTT--T--
--PDPTTT-----------------PHPTTTPDPTTTPH-----P-TTTPDPS--STPII
-TTKSLPTSLGTELSSPTLAPTVRPSLHPQLTFTAPAPHTSTSQMPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPSLTPPPTHTPHSASDLTMSP----DPHLSPIAHP
LDHPPLDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAAQGLGQLGEAV--------------
---------------------------------KRLAEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LGDLS-SVPAERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 442)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGGEQQLGLCPHR---GWKAH
IC------S-HEEDAGVVC--

ENSGT00900000140803_2_Linker_2_3 (442, 527)

QRGTDSRDHDDPSSVLDGDPWPGPAGELSAGSEEPPVTP
AARPAGTPQS--GSRKKSPRLPKPAKSTRAPVLTAGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGTVCD--DG-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--AA
GSNSSGPRGAASR-PPPP------------------------------------------
---------------MVSLAPWTPG-----VSAPPVPPT-------ALQEPGPD--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HAG---RWGTVCDDGWDLRDAAVVCRELGCGGPR
QPDPTAGRFGWGAGPIWLDDVRCTGTEAALADCPASPWGKH---NCAHNEDVGVTCAGTP
GLDSISDPFSWSWIPGLGRDVDAWLPGELATKPS----ARRTPSIPEKTTTKAPGKTPKS
TKKWVTKNAKRPTTQPPAMPTTKHSRVSGTQSTPELTSRTTSTSTLAMGAS---RRPTSE
FTTRLTTQAPRRLTSHSTVTRTSRAPRERTSKTVVTPATQGPRLVTSEAT---------V
EPS-----A-ELPGQGSPESSTD---PAPSPTGA-----AGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDGWDLRDGMVACWELGCGRVRPRV----GKTHYGPGSGPIWLDDVGCK
GSESSLSDCPARAWGQH---NCDHEEDVGLTCTGYADEEDYPPWTWDPTSGEDLAKGTTA
AGVPGHTLSRET-TGSPGAPA---PARRRLPST--GDKDCREPSRTGDT-PSGGVPA---
KETPTAATPGP---PGTTRSSGHPSLAPRLRGDTGSLRRR-----WPERR-LR--PTTA-
RTA-PAAPSPPRSAAPGPADPPL---T---STSAPPLIR-TAAS--TPEETPDGTSAVPS
-----SPAAASR--GSAHR---------TSTSPGLT-------VPSPDASAPP--APTSG
LSPTPPPTAPRE----------------LTSDPSSPAAATHLSPTSGL-TPE---PDRAP
GRGTSPQPSAVPE--------PSSSPDRSTGPHPTTAPYSTMTSHPAATSHPTSAPYSTM
TFHPAATSHPTTAGYSTMTSH-PAATSHPTTAPHSTMTSHPAATSYPITAPYSTMTSHP-
----------AATSHPTTAPYSTMT-SHPTTAPYSTMTSHPTTAPYSTMTSHPTAISHPT
TTLYPTSTPHATTTPYPTTTPYPTTTSHPTTPYPPTS-THSTSTPHPTTTPPPI------
--TTPITT-----------------PHPATTPHPAKTSH-----PTT--PHPI--TTP--
---------YPTTTPQSPSPSLVKPSLHPQMTFMG-APRPSTS--------------PAS
ESSLSPAPSMDILSTENFKPTTSQSPQVTSPPTQTPHSAPDPTVTPVGSSGDHLAPMAHP
LDQPPPDHLSLGPAPSPSSGPPGPCEAPVP-----PVRVMACEP-PALVELVAAVRDVGS
QLQRLT------QALERDQQERRALGLGLTQLVEAAQGLGQLGEVV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPTTPVPTTTTPEW--EDRPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MMDV
QCQGTEAALGTCTYKH-AENL---CEHFEDV------GARCQD-----------------
------------------------------------------------------------
--------------------VRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 882)

VGGPHSCAGR-----VEVLVAGRWGTVCD--DG-WDE
KDVAVVCRQLGCGQAVESLSSDVFGPG-----S-ESQP-------------VLLTDVQCQ
---G-------TEAALGTCTYEDP-GGNC---DHKEHVGARCHEVPKVPV----------
------------------------------------------------------------
------------------------------------------------------------
-RLV--G-----SN

PF00530 // ENSGT00900000140803_2_Domain_8 (1035, 1360)

ATRCSGQVEIF-HQG---RWGTVCGLGWDLTDAKVLCRELGCGTPR
YITQSCLKFSRSSEPILLGLLDCTGHETSLTQC---------------------------
-------------------------------------------------------QF---
-QDWAEKP----------------------------------------------------
------------------------------------------------------------
--C---PY-----------------------HRDTGVKC

ENSGT00900000140803_2_Linker_8_9 (1360, 1368)

QEPFALRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VD-GPGRCAGRLE
VQYDGEWGTVCDDHWSNSSADVVCRELGCGPAEPMVAKLRDRPRFGKATGRIWLDDVRCK
GTEKTLQNCAHRVWGYH---DCTHHEDISVVCQES-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILT--
-ICIRPGFL----------ASPSRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEVEQ-KGQWGTVCADGWDKNEV
AVLCRELGCGDANGTPS-GYLYEPPAEKTQEVLIQEIRCTGTEDTLAQCEQ----EAAY-
DC------S-HDEDAGASCENS--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRIEVK-HQD---QWYSVCQAGWNLRATKVVCRQLGCGRAV
LTQKRCHKPAQGQRPIWLSQMSCSGREATLQDCPSGPWGSN---SCNHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AFALRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHRGVWGSVCDDGWGAKEDQVVCKQLGCGQSL--SPSFKDRKSHGPGVGRIWLDDVRCS
GEEQTLEQCQHRFWGYH---DCTHQEDVAVICSEEYPGVLH-------------------
-----------------A------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------IRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VNGPNRCTGRLEVLW-NQQWGTVCDDSWDLPDA
MVVCRQLECGEALSAPG-LAQFGQG---TGRIWLDDMNCNGTEVDLSACR-TR--PWGEH
NC------N-HGEDAGVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SGLN-------------------------------------
------------------------------------K--TVPIRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VNGTSHCSGRVEVFY
GHQWGTVCDDNWDIVDAEV-VCRQLGCGT-----ALSAPSSAYF----GRGSEPIWLDEV
ICRGTEAALSECSTKPWGLHD---CVHGEDA------GVVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

SGF----------------
------------------------------------------------------------
-------------AKP--APLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VDGLTPCSGR-----IEVFYGQRWGTVCD--DD-WDL
VDAEVVCRQLGCGKALSAPHRAYF--------GQGSDP-------------IWLDNVNCT
---G-------TEAALSECMATPWGVHNC---GHGEDAGVVCE-----------------
------------------------------------------------------------
---------------------------------------------------------EPV
PVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGSNFCSGRVEVF-HEQ---QWGTVCDDSWDLADAQVVCRQLGCGAAI
S-APGSAQFGQGTGQIWLDDVNCAGAESVLTECRAKPWGDH---NCNHKEDAAVECSD--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------V--------AETA--PIRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GPSHCAGRVE
VFHDQQWGTVCDDGWDIAEANVVCRQLGCGAALSAP----GSARFGEGSDPIWLDDVNCI
GTELHYTISKLYSA----------KYGTQTIS

ENSGT00900000140803_2_Linker_9_11 (1473, 1517)

LD--------------------------
------IPRVAP-LQL

PF00530 // ENSGT00900000140803_2_Domain_11 (1517, 1734)

MDGPN---HCSGRVEVFY-GQQWGTVCGDSWD-IRDAEVVCQ--
-Q-LGC--------GKALSTPASA------------------------------------
------------------------------------YF----------GKGSGPIWL---
-DDVNCRGTETA------LSKCE--------TSLWGARN---CSHGEDAGVVCLDEL---
---------LATLTACKTG-------------VIH-------------------------
-------------------------PMTIKGP----------------------------
------------------------------------------------------------
-------Q-W----------------SC---KSVP--------------------EP---
--------------VPVRL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2237)

VNG----------------------------SNFCSGRVEV
FHEQQWGT---------------------VCDD----SW-----------DLA--DAQV-
-VCRQ--LGCGAAI--------------------------------------------SA
PGSAWFGQGTGQIWLDDVNCAGAETA------------LSDCKARSWGD-----------
H---NCNHKEDASVFC

ENSGT00900000140803_2_Linker_15_16 (2237, 2272)

SG--VA----------------------EAAPIRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VNGSSPCAG
RVEVF--HDQQWGTVCDDGW----------DTADANVVCRQLGCGA-------ALSAPGS
AHFGEGSNPI-------WLD--DMNCIGTEAALSECQFQPWGSHN---CRHGEDAGVVCS
E-----------------------------------------------------------
------------------------------------------------------------
-----------------------------------IAPLRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2662)

VNGPTRCAGRVEVLQSQQW
GTVCDDNWDLSDAEVVCQQLGCGKAMSAPGSAYFGQGYGRIWLDDVKCSGKESALSKCVA
RPWGVHN---CNHGEDAGVICS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGLL----------GPPPRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VKGSHSCEGRVEVEQ-QGHWGLVCDDGWDMNDV
AVLCQELGCGVAKRAIS-GNLYKPLPKEDQKILLQNVDCSGTEKTLAQCKKD---EDVF-
GC------S-LDEAAGAVCENL--------------------------------------
---------------------------------------ES-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------PV----------------
------------------------------------------------------------
----------------------------------------------------------FE
DVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGQCQGRVELK-HQD---EWNAVCLTGWNLQAAKVVCRQLGCGRAV
LTKKHCEESAQGQRPIWPSQMSCSGQEVSLQDCPSRPQGKS---NCTFDDQVWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AFDLRLA--

PF00530 // ENSGT00900000140803_2_Domain_9 (1371, 1473)

GDKPCSGRLE
VLHKGVWGSVCDDGWGAREDQVVCKQLGCGKPL--SPSPKDRKSYGPGVGRIWLDDVRCS
GKEQSLEYCQHRFWGYH---DCTHKEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILT--
-VCIRPGFL----------ESPSRVRLV

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

EGPHRCEGRVEVQK-KGQWGTVCDDGWDKNEV
AVLCRELGCGDANGTPS-GYLYGPPAEKEQAVLIQEIRCTGTEDTLAQCEQ----EAAY-
DC------S-HDKDAGASCENP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NIRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQD---QWYSMCQSDWSLRTAKVVCRQLGCGRAV
LTKKRCHKPAQGRRPIWLSQMLCSGREATLQNCPSRPWGSN---SCNHDGDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AFALRLVG

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

GGDKLCSGRLE
VLHKGVWGSVCDDGWGEKEDQVVCKQLGCGQSL--CPSFKDRKSHGPGVGRIWLDDVHCS
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSE--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LVLSMHKELE---
----------------------AM------------------------------------
------------CCCFLG----------------------------RS------VSPESE
ELRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-SDHGRCAGRVEVL-HNG---IWGTVCGDNWDAHDGQVVCRQLSCGTLL
S-VSRGARHGEGTGPIWLDDVNCTGTEAALSECQARPWGHH---NCVHMEDASVEC

ENSGT00900000140803_2_Linker_6_8 (1137, 1176)

SV--
-------ELR------------------------L

PF00530 // ENSGT00900000140803_2_Domain_8 (1176, 1360)

VNGS-TRCNGR---------VEVFH
NDTWAALCDDGWGMSE--AQVVCRQLGCGEAL-----------LAPVGSHFGQGSGQMWP
GTIN----------------------------------CTGSESALF-------------
------TCKTRQWSNSTCH-LR--TSAGV--------VC

ENSGT00900000140803_2_Linker_8_9 (1360, 1368)

SEPAHLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GSHHCAGQVE
VFHEEMWGAVCDHGWDKKDAEVVCRQLGCGTALSAS----GEAHLDAGSLRVWLDNVSCE
GTELSLTKCRASPWGKS---SCSRGKHASVVC

ENSGT00900000140803_2_Linker_9_11 (1473, 1517)

SGGFQCIGL---GWDILAAP-IRSGPLP
PSHCSVVSSFAP-VRL

PF00530 // ENSGT00900000140803_2_Domain_11 (1517, 1734)

VDGPG---RCAGRLEVFH-KEQWGTVCDDSWE-FTDAAVVCR--
-Q-LDC--------GAVISTPPRA------------------------------------
------------------------------------YF----------GQGQGPMWL---
-DDVNCTGTEAA------LSECK--------FKGWGIHN---CYHHEVVSVVCSGS----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------GIS--------------------DL---
--------------ADLRL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2237)

VNG----------------------------FDKCSGRLEV
FHDQRWGT---------------------VCAD----GW-----------DLA--EAYV-
-VCRQ--LGCGAAR--------------------------------------------SA
SSFSRFGRGSGPIWLEGVRCFGTEAT------------LTECPVKPKGL-----------
H---SCSHLEDAGVVC

ENSGT00900000140803_2_Linker_15_16 (2237, 2272)

SGSGTS----------------------NISTLRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VDGLSECAG
RVEVF--YNNEWGTVCDDNW----------DMNDAAVVCRQLGCGT-------ALSAPGS
ARFGWGHSRI-------WLD--EVRCTGEENDISQCAAKTWGVHN---CHHGEDAGVVC

ENSGT00900000140803_2_Linker_16_17 (2400, 2408)

S
A--DVRL

PF00530 // ENSGT00900000140803_2_Domain_17 (2408, 2524)

VNGP---SRCAGR-VEVLHNGQWGTVCDDGWD----LNDAKVVCRQLGCG---
-----TVLSAPGRAYFGQGTGY-IWLDDDDVNCAGTEDALHQCRARPWGMNNCNHREDAG
VVC

ENSGT00900000140803_2_Linker_17_18 (2524, 2562)

SEI-----------------------------TAKVRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2662)

VNGPHRCAGRLEVFQNERW
GTVCGNGWDMNDAIVVCRQLGCGIALSAPVQAHFGQGSDPIWMNRVSCIGTESSISECLS
SPWGIQL---CTHMDDAGVEC

ENSGT00900000140803_2_Linker_18_19 (2662, 2702)

SGELWMPHCWRQL-NGSKGSSFKHEGVCILQTDDTSTLR
L

PF00530 // ENSGT00900000140803_2_Domain_19 (2702, 2809)

VNGPHRC-----SGRV--EVFHNQQWGTVCDDGWDMNDAMVVCRQLGCGEALSATTQAS
FGRGVDPIWLDRVACTGRENALVQCRARP---WGVNVCTHEEDAGVVC

ENSGT00900000140803_2_Linker_19_20 (2809, 2832)

SAE---------
-----AAEIRL

PF00530 // ENSGT00900000140803_2_Domain_20 (2832, 2933)

VNGPSRCAGRVEVLHDGQWGTVCDD-GWNLQAATVVCRQLNCGRAESAP
RGARFGQGTGHIWLDDVNCAGTEDALHQCQARPWGM---NNCNHREDAGVVC

ENSGT00900000140803_2_Linker_20_21 (2933, 2955)

SENHTSPL
AEDSNTTEEMQIRL

PF00530 // ENSGT00900000140803_2_Domain_21 (2955, 3052)

VNGPNRCAGRVEVFHNRQWGTVCDDSWNLRSAKVVCRQLGCGTAAS
APGKAHFGRGSDPIWLDDVECSGTEASLSQCRLNNWGNHNCNHEEDAAVVCSG-------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MAPLF-NLMLAIL
SIFVGSCFS----------ESPTKVQL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGAHRCEGRVEVEH-NGQWGTVCDDGWDRHDV
AVVCRELNCGAVIQTPR-GASYQPPASEEQRVLIQGVGCNGTEDTLAQCELN---YDVF-
DC------S-HEEDAGAQCENP--------------------------------------
---------------------------------------DSDL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LFI----------------
------------------------------------------------------------
----------------------------------------------------------PE
AVRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

DGPGHCQGRVEVL-HQS---QWSTVCKAGWNLQVSKVVCRQLGCGRAL
LTHGSCKKSTQGKGPIWMGKMSCSGQEANLRSCLLSRLE-N---NCTHGEDTWMECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1472)

VG-GDTPCSGRLE
VLHKGSWGSVCDDNWGEKEDQVVCKQLGCGKSL--LPSPKTRKIYGPGAGRIWLDDVNCS
GKEQSLEFCRHRLWGYN---DCTHKEDVEVICTDFDV-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPAFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVKQ-NGQWGTVCDDGWDIKDV
AVVCQELGCGAANGTPS-GILYEPPAENEQKVFIQEVGCTGTEDTLAQCEQ----EEAY-
NC------L-HNEDAGALCENP--------------------------------------
---------------------------------------ESPF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---QWYSVCQTAWSLRAAKVVCRQLGCGRAV
LTQKRCNKPAQGQRSMWLSQMSCSGREATLQDCPSGSWGKS---TCIHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFKDRKSYGPGVGRIWLDDVHCS
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-PLILA--
-ICTRPGLQ----------ESPSRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEIEQ-KGQWGTVCDDGWDMKAV
AVVCRELSCGAAKGTPS-GVSYEPSAEEGQSVLIQEVKCNGTEDTLAQCDLD---EDVF-
EC------S-YKEHAGASCEKP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PLV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----V

PF00530 // ENSGT00900000140803_2_Domain_6 (1034, 1137)

GPGHCQGLVEVK-YQN---QWSTVCQTGWNLQAAQVVCRQLGCGRAL
MTERRCSKATQGQRRIWQRQISCSGREVTLQDCPSGSWGKN---ICTHDEDTWVECEG--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AFELRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDGWGEKEDQVVCKQLECGKSL--SPSSKFRRRYGPGVGRIWLDDVQCS
GEEQSLEQCRHRFWGYH---DCTHKEDVAVICSGK-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLIFA--
-ICTGPGLS----------ESSPRLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGPHRCEGRVEVER-DGQWGTVCADDWNLEAV
AVVCRELGCGEAKEPLS-GAAYLPSEDNEQQVLIQDVSCNGLEDTLDQCKKT---EDGF-
NC------W-RNHTAGARCDXX--------------------------------------
---------------------------------------XXXX-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------XXX----------------
------------------------------------------------------------
----------------------------------------------------------XX
XXXX--A----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPGRCKGRLEVG-HQG---QWSTVCKAGWNLQDAKVACRQLGCGRAV
LTKRCCSKATQGQGPIWLSQMSCSGQEATLQDCPSGPWGKI---SCTHDEDTWVECEEPE
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------N---L---------------
------W---------------------------------------PGL-DAFGDD

PF00530 // ENSGT00900000140803_2_Domain_10 (1437, 1473)

VYCS
GEAL-SEQCQHRFWGFN---DCSHKEDVAVICSE--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-IYTRPGFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVEQ-KGQWGTVCDDGWDIKDV
AVVCRELGCGAASGTPS-GILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQ----EEVY-
DC------S-HDEDAGASCENP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
GVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---QWYTVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKN---TCNHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDNLCCGRLE
VLHKGVWGSVCDDDWGEKEDQVVCKQLGCGKSL--SPSFRNRKSYGPGVGRIWLDNVRCS
GEEQSLEQCKHRFWGFH---DCTHQEDVAVFCSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------PIRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VDGPNRCAGRLEVLW-KQQWGTVCDDRWDLSDA
MVVCMQLDCGKPLSAPG-LAHFGQG---TGPIWLDDMKCNGTEVDLSACRTR---SWGEH
NC------N-HGEDASVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SVFNA------------------------------------
-----------------------------------GNSEAAQLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VNGTNHCSGRVEVLY
GQQWGTVCDDSWDLLDAEV-VCRQLGCGT-----ALSAASSAYF----GRGSDPIWLDDV
MCKGTEAALSECTAKPWGKHN---CGHGEDV------GVVCS------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------IRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VGGPNLCSGR-----VEVFLSGQWASVCD--DS-WGI
EEAMVVCRQLGCGSAVSATHEAQF--------GNGTVS-------------IGLDDVRCR
---G-------TESALSECPASPWGEHDC---SHEETAGVICSD----------------
------------------------------------------------------------
----------------------------------------------------------QT
EIRL----------VD

PF00530 // ENSGT00900000140803_2_Domain_6 (1037, 1137)

NCSGRVELL-HHG---EWGTICGDGWGIEEATVVCHEMGCGTGS
M-NQSRTWNGSGTSPIWLDGVHCRGTESSLLQCSASPLGRH---GCDSGETASVVCSGKF
INYGP-EC----------------------------------------------------
----------G-------------------------------------------------
------------------------------------------------------------
------------FDSSEFQPSFVSQTARE--------YVSPQSEVRLID

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPTPCTGRVE
VFHNKAWGTVCDNGWDLEDASVVCQEVGCGEALVAA----IGARFGQGSGPIWMDEVNCT
GKEKVLKKCPQEKSLSL---TCDHRKDVGVE

ENSGT00900000140803_2_Linker_9_11 (1472, 1518)

CAA--------------------------
---------FSV-MRLA

PF00530 // ENSGT00900000140803_2_Domain_11 (1518, 1734)

DGRH---RCTGRVELFL-DGQWRMVSYRRWD-LKEPWVVCR--
-H-LGC--------EAAPHPLMYP------------------------------------
------------------------------------IY----------GEKTPSIWM---
-DGVQCTGTETS------FSECE--------ITPWQESDLDRLLPFYVAGVTCT------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------D---------------------------
----------------ARL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2237)

VNG----------------------------PNRCSGRVEL
LHNQEWGT---------------------VCDA----SW-----------DIY--DAQV-
-VCRE--LGCGNAL--------------------------------------------KA
FRGAHHGQGFGPIWIEGVNCTGKEAS------------LSECNRSPWGE-----------
H---HCSHSQDASVEC

ENSGT00900000140803_2_Linker_15_16 (2237, 2272)

TG-----------------------------WIRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VNGSSRCSG
TVEVL--RNQHWKAICDKNW----------GSYEDHVVCREMDCKG-------ITWYPID
GFRS---GHR-------ISS--ILFCRWTANDLSECGLTDFDEES---CSHGRAAAVMCS
E-----------------------------------------------------------
------------------------------------------------------------
-----------------------------------PTGTRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2662)

VNGTNRCSGRVEMFFNEAW
GTVCDSGWDLREAQVVCRELDCGGALSAPGGSLFGTGKYGRWSYEPKCLGTEVTFQKCMF
DSR--HF---CRSFETAGVVC

ENSGT00900000140803_2_Linker_18_19 (2662, 2702)

SGNCKYSLVKA--NNSMFAHNLIT-INLLLYFIFSKDLR
L

PF00530 // ENSGT00900000140803_2_Domain_19 (2702, 2809)

MNGTSPC-----SGRV--EVFHNDTWGTICDAGWDLQDAQVICREKGCGNASKASGGAH
HGQGSGPIWLESINCTGEEASLKECQKGG---WGEHSCSHSQDASVEC

ENSGT00900000140803_2_Linker_19_20 (2809, 2832)

SGFK--------
-----SLETRL

PF00530 // ENSGT00900000140803_2_Domain_20 (2832, 2933)

VNGPNRCSGRVEVLRNGVWGTVCDD-GWDLSDAQVVCRELSCGGAVSAP
EGAHFGKGNDPILINEVQCRGTEVSLYNCIY---KMHRFHECRHEEDAGVVC

ENSGT00900000140803_2_Linker_20_21 (2933, 2955)

SGKLVKNC
IFEAGWRDREDLRL

PF00530 // ENSGT00900000140803_2_Domain_21 (2955, 3052)

MNGTSPCSGRVEVFHNDTWGTICDAGWDLQDAQVVCSQLGCGKASK
ALGGAHYDQGSGPIWLENINCTGDESSLKECQKGIWGEHSCSHSQDASVECSVIITAVES
SLESSVHLGVAALVFLALVGIVAEAGCRRRRKTRREEQL---------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------GPF-RLLL--G
PQLIVHLLA----------ESSYRARL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGSHRCEGRVDVEQ-NGQWSTVCGYNWDLKNV
VVVCRELGCGAAKGTQS-SFTYKPQAEENQDFFIEEFHCKGLEDTLAQCEKE---DTDYG
SC------S-HQDYAGASCEKC--------------------------------------
---------------------------------------DLGM-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LYC----------------
------------------------------------------------------------
----------------------------------------------------------SQ
RLRL--A----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPGRCIGRVEVK-HQD---QWGTVCKAGWNLQAAKVVCRQLGCGKAT
LTRGNCKRATQGQGPIWLNQVSCSGKELTIQDCPSRPWGKN---NCTHDEDTWVHCEDTT
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------DPFELKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

EG-GESHCSGRLM
VLHKGIWGSVCDDGWGRKENQVVCKQLGCGHPL--LLPFGVQKHFGLGVGWMMLDDVRCS
GNELSLEQCRHRFWGYH---DCTHCDLLSIVCDSHGS-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ASPPGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVRQ-NGQWGTVCDDGWDIKDV
AVVCRELGCGAANGTPS-GILYEPPAENEQKVFIQEVSCTGTEDTLAQCEQ----EEAY-
NC------L-HNEDAGALCENP--------------------------------------
---------------------------------------ESPL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---RWYSVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKPAQGQRSIWLSQMSCSGREATLQDCPSGPWGKS---TCIHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLDCGKSL--SPSFKDRKSYGPGVGRIWLDNVRCL
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLV-SLILA--
-ICTRPGFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVRQ-NGQWGTVCDDGWDIKDV
AVVCRELGCGAANGTPS-GILYEPPAENEQKVFIQEVSCTGTEDTLAQCEQ----EEAY-
NC------L-HNEDAGALCENP--------------------------------------
---------------------------------------ESPL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---RWYSVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKPAQDQRSIWLSQMSCSGREATLQDCPSGPWGKS---TCIHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--FPSFKDRKSYGPGVGRIWLDDVRCL
GEEQSLEQCQHRFWGYH---DCTHQEDVVVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGHEGQLGVCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--NSASPLDGAPWPGLSVELGPSTEENPVTH
APRPAGNPQN--ASRKKGPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDATV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPMVP--TV
TSNDSISREAASR-PLST------------------------------------------
---------------VTSQAPGTAG-----VSPPLASPT-------VPWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGHFGWGAGPIWLDDVGCVGTEALLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRNAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKNAKRPTTQPPVTPTTKHSRAQ---SPPDLTSQTTA-A-LITEAS---RRPTFE
FTRRPTTEAPHRWTSHSTAMLTPQTPRERTSKTMVMLTTQSPREMTSEATIKR-VPQASL
EPS-----A-EIP-QE---SSKD---PAPSPTASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGHWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGEWGKH---NCDHEEDVVLTCTGYADYDDYPPWTWDPTSAEDLAKGTTT
VGGPGHTLPWGT-TRHPETPF---PATRRLPDT--GGRDGYKLPWMWDT-ASGRGLA---
EGTPTLGKLGPTVGAGITRSPGSP-PAPRVHGDTGSPRKP-----WPEGRPPR--PTAI-
RTA-PPTPSTGPSASPGPPGPAL---T---SDSSLELTP-RSAL--TPEATSDPADTS-P
-----TSDPASR--TNPDL---------ILTSPDFA-------LSTPDSNVVP--SLTPE
LSPTPPPTLLKE----------------LTSDPSTPLEVTSLSPTSER-TPD---SDTTS
DLDTTPYPSTVSE--------YSRSPDPSPSPHSTITPDPTVTPGPTTTP------HPTL
TSHPTMTPHFPTTTHPTTTPQ-------PTTIIHSTTTPDPTTTPQ--------------
------------------------------------------------------------
----PTTIIHSTMIPDPTTTP------------------------QPFATMQPTT--T--
--PQPTTT-----------------T----TTHSTTTRH-----P-TTTPDPS--STPTI
-TTKSLPTSVGTELSSPTPAPTVKPSLPPELTFTAPAPHPSTSEMPTLEP---SPALESR
SSRSSTATSIDPLFTEDFKPSRSQSPSLTPPPTHAPHSASDLTVSP----DHHLSPIAHP
LDQPPLDHLTLGPTPGQSPRPHGPCVATTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQERQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRLAEVT--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPTMPAPTTTTPEA--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRIL--------
-ACL--------LAALLGIHCAERLRLS

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

SGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGAEDRLSLCPHR---GWKPH
VC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CVGHRAASSRV--DPDPPQAGGLWPGLLGRLNPGPEATPTPH
APHPAGTPNS--SLRRKGLRPGKPPKPNRKALAATDAPQEERLRLS

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
AGRWGTVCDDGWDLRDAAV-ACRELGCGR-----ALTAPGAARF----GEGAGPVWMDDV
GCGGEEPALRDCPRSPWGRSN---CDHSEDA------GVV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CAG-----------------
------------------------------------------------------------
----------------PAPRLRLS

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

SGPHGCAGR-----LEVWHGGRWGTVCD--DG-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETGLRLCPSRPWGQHDC---HHREDAGLVCDGLPLS-FSAPAPP---P
GSGPHLPGTATTKTPPLT------------------------------------------
---------------GTPRTPGDAGKKRG-DSLPSASPT-------LPRVEAPLVSEGRR
GDVLPTVSPMDPQEPGRGEGKPPSLQKNGICPRLLTTSETPDRIRRSCPLCSLE------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-FLILA--
-ISTGPGLL----------ESSSSVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VRGPHHCEGRVEVKR-NGQWGTVCDDGWDLTDV
AVVCRELGCGAANGTPS-GTLYKPLAEENQPVHIQDVDCNGMEDTLAQCVQD---DDVF-
NC------F-HNEDAGASCE----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------I----------------
------------------------------------------------------------
----------------------------------------------------------PE
TVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPGRCTGRVEVK-HQD---QWGTVCQAGWNLRAAKVVCRQLGCGRAI
LTRACCDKACQGQGPTWLSQVSCSGRELTLHSCPSRPWQKN---NCTHEEDAWVQCED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELKLEG

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-GEHRCSGRLA
VLHKGEWGSVCDDGWGETENLVVCRQLGCGEPL--LSIAKAKKQFGPGVGRIWLDEVRCS
GMEQSLEQCQHRFWGYH---DCTHKEDVAMNCSPFRPS----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVEQ-KGQWGTVCDDGWDIKDV
AVVCRELGCGAASGTPS-GILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQ----EEVY-
DC------S-HDEDAGASCENP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
GVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---QWYTVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKHAYGRKPIWLSHMSCSGREATLQDCPSGPWGKN---TCNHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDNLCCGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFRNRKCYGPGVGRIWLDNVRCS
GEEQSLEQCQHRFWGFH---DCTHQEDVAVFCSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-FLILA--
-FCTGLGLS----------ESSSRTRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGRHRCEGRVEVER-DGQWGTVCDDGWDMKDV
EVVCRELGCGAATGTPS-GTLYKPLAEKDQKVLIQAVNCSGMESKLIHCEQE---EDVF-
DC------S-HNEDAGVMCEI---------------------------------------
----------------------------------------V-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------PE
TVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-GGPGRCKGRVEVK-HRE---QWGTVCKAGWNLSAAKVVCRQLGCGRAT
LTQRCCNKDTQGQGPIWLSKVSCSGQEGNLHDCPSGLWGNN---NCTHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDTRCSGRLE
VLHKGEWGSVCDDGWGEKEEQVVCKQLGCGESI--FLSAKARRNFGLGAGRIWLDDVHCS
GKEQSLEQCRHRFWGHH---NCNHKEDVAVTCLEL-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------QLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VGGGGRCAGR-----VEVEHGGEWGSVCVNDFD-WEP
RIGEVVCRLLGCGRVARVSPYARF--------GQGTGR-------------IWLQLLLCR
---G-------GESALEECTHFGWGRHIC---GHERDVGVICT-----------------
------------------------------------------------------------
---------------------------------------------------------DAV
ELRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-GGSSPCAGRVEVK-LQG---QWGSVGDDDWDKEDAEVVCQQLGCGSAS
KDYYARDRFGLGGWLISLTQVDCSGYEATLWDCEIRGWGPYN--SSIRYWHTAVVC

ENSGT00900000140803_2_Linker_6_8 (1137, 1176)

QG--
-------FSR------------------------L

PF00530 // ENSGT00900000140803_2_Domain_8 (1176, 1347)

VGGD-GACAGR---------LEVRR
GRAWVGVCEDQVDMKA--AQVVCRELGCGEAL-----------AIPGSARFGRGSGSLWV
GGFQ----------------------------------CNGTESLLS-------------
------ACARRLPLSQACAGPASVIC

ENSGT00900000140803_2_Linker_8_9 (1347, 1370)

S-------------AYTGFRLGN

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-SSSGCSGRVE
VAVRGTWGSVCASEWDLADAHVLCRHLGCGRASSVP----PGGSFGSGEGTLRPDAFGCH
GSERHPGECPVAVLGKP---PCVPGNAAAVKCSGN-------------------------
---------WTG-LMLSVDLI---------------------------------------
------------------------------------------------------------
--------------------------------------------------TTAPA-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------D-----------------------
------------------------------------------------------------
-------------------------IPHGNYITCS--------------------GS---
--------------RQVRLA

PF00530 // ENSGT00900000140803_2_Domain_15 (2001, 2237)

GS----------------------------SGRCAGRVEV
YSGGSWSS---------------------VCQE----GW-----------ELQ--DAAV-
-VCRE--LGCGTAL--------------------------------------------EA
PSRARFGAGTGPLWPYVPDCSGSEES------------LWECRRTER-------------
R---ECGRGGGAGAVC

ENSGT00900000140803_2_Linker_15_16 (2237, 2273)

SE---------------------------QLSVRLA

PF00530 // ENSGT00900000140803_2_Domain_16 (2273, 2381)

GGPGRCRG
YLEVS--YNGTWGRVCANGT----------RTGTAAAVCRQLGCGH-------LGRLSA-
-VPTQQPSLA-------WLA--WVGCEDGARSLWECPSAPW-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

LR-------L

PF00530 // ENSGT00900000140803_2_Domain_0 (11, 181)

LDGPHRCAG-----------------------------------------
------------------RVE-VYYSNRW-GTVCDD-QWDLD-DANVVC-RQLHC-GIAL
S-TSRPGE-FRAGSGP-IWLDD-VNCTGT-EVALS-YCRANDWGKT-NCHHGED-AGVVC

ENSGT00900000140803_2_Linker_0_1 (181, 191)

AGSTE-LR-L

PF00530 // ENSGT00900000140803_2_Domain_1 (191, 320)

VNGP---------------NRCAGRVELLYGHEWGTVCDDDWSFTDAKVV
CRQLGCGTAVSAYSSAYFGQGTGPIWLDNV---QCSGTEA--SLSECQAKP---WGVN--
-NCDHGE-DAGV-----VC

ENSGT00900000140803_2_Linker_1_2 (320, 328)

AVPAQLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

QNGPSRCAGRVEVLH-EHQWGTVCDDGWSLSEA
TVVCRQLSCGTAVSAPV-LAHFGPG---SGRVWLDNVNCTGAEAALSECH-AR--PWGSN
DC------D-HGEDAGVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SGH--------------------------------------
----------------------------------------RLLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VNGSNSCIGRVEVLH
DQKWGTVCDDTWDINDAAV-VCRELGCGT-----AMSAPGSAHF----GQGSDPIWLDNV
HCVGTESTFAECGLKSWGEHN---CGHSEDA------GVVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

SGK----------------
------------------------------------------------------------
-------------STD-PEGLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VDGPGRCAGR-----VEVLHNGTWGTVCD--DN-WSV
HEGQVVCRQLGCGTVLSVSKGARH--------GEGMGQ-------------IWLDDVNCT
---G-------TEAALSECQSRPWGQHNC---HHVEDASVECSGSP--------------
------------------------------------------------------------
---------------------------------------------------------SAP
PLQL--L----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGPNRCAGRVEVL-HDH---MWGTVCDDGWDLMDATVVCRQLGCGTAL
M-ATKGAHYGRGQDPIWLDEVNCTGTEATIFDCKARAWGVN---NCYHGEDAGVVC

ENSGT00900000140803_2_Linker_6_8 (1137, 1176)

SGNS
CLDLP-TQLR------------------------L

PF00530 // ENSGT00900000140803_2_Domain_8 (1176, 1360)

ANGT-TRCNGR---------VEVFH
NATWAALCDDGWGLAE--AQVVCRQLGCGTAL-----------LAPGGSHFGQGSGQMWP
GSVN----------------------------------CTGAETALF-------------
------ACKMRPWSNSTHH-PR--TSAGV--------VC

ENSGT00900000140803_2_Linker_8_9 (1360, 1368)

AEGDQVRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-YGSRCAGRVE
IFHNKQWGTVCDDNWDLLDANVVCRQLGCGRALSAP----GWAQFGQGTGVIWLDETNCT
GFEYALSTCWARQWGIN---NCYHGEDAGVVC

ENSGT00900000140803_2_Linker_9_11 (1473, 1517)

SG--------------------------
------L---AP-VRL

PF00530 // ENSGT00900000140803_2_Domain_11 (1517, 1734)

VDGPG---RCAGRVEVFH-NDQWGTVCDDSWE-FPDAEVVCR--
-Q-LDC--------GVVISAPRRA------------------------------------
------------------------------------YF----------GQGQGPIWL---
-DDVNCTGTEAA------LSECK--------LKGWAVHS---CDHDEDASVVC

ENSGT00900000140803_2_Linker_11_14 (1734, 1754)

SDLG---
---------ELRL

PF00530 // ENSGT00900000140803_2_Domain_14 (1754, 1947)

ANGSDK-------------CSGRLEVFHDQRWGTV---------CAD
GWDLAEAHVVCRQLGCGAARSATDSPQFGKGPDLLWVDAVQ---CTGT------------
--------------------------------------------------------ERAL
F--ECKVKLWGAQ-NCKSRGYASVVC

ENSGT00900000140803_2_Linker_14_15 (1947, 2000)

SD---ADLG--------------------SP---
--------------EALRL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2237)

VNG----------------------------PNRCSGRVEV
FHSWQWGT---------------------ICDD----GW-----------DLN--DAKV-
-VCRQ--LGCGTAV--------------------------------------------SA
QGLSSFGQGSGPIWLEGVRCLGTEAT------------LAECPFKPWGL-----------
H---TCSHMEDASVVC

ENSGT00900000140803_2_Linker_15_16 (2237, 2272)

SGSGIS----------------------TTTTLRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VGGLNKCIG
RVEMF--YNNEWGTVCDDSW----------DMSDAMVVCRQLGCGT-------ALSAPGS
ARFGWGSGRI-------WLD--EVNCTGEENDISQCKAKTWGVHN---CHHGEDAGVVC

ENSGT00900000140803_2_Linker_16_17 (2400, 2408)

S
A--ELRL

PF00530 // ENSGT00900000140803_2_Domain_17 (2408, 2524)

VNGP---SRCTGR-VEVLHDGLWGTVCDDGWD----LNDGKVVCRQLGCG---
-----VVLSAPGRARFGQGTGH-IWLD--DVNCVGTENTLSHCRASPWGRNNCNHREDAS
VVC

ENSGT00900000140803_2_Linker_17_18 (2524, 2562)

SEPD------------------------T-SKSSLLRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2662)

VNGPNRCTGRVEVFHDGQW
GTVCDDGWDLRAATVVCRQLGCGRAESAPSGARYGQGTGHIWLDDVNCAGTEDTLAHCQA
RPWGQNN---CNHGEDAGVVC

ENSGT00900000140803_2_Linker_18_19 (2662, 2702)

SAN-------------------------------RSTIR
L

PF00530 // ENSGT00900000140803_2_Domain_19 (2702, 2809)

VDGPHRC-----SGRV--EVFHNQQWGTVCDDGWDLNDAAVVCRQLGCGAAVSATAHAS
FGRGMDPIWLDRVACSGRESALTECRARP---WGINSCNHEEDAGVVC

ENSGT00900000140803_2_Linker_19_20 (2809, 2832)

SGD---------
-----AHNVRL

PF00530 // ENSGT00900000140803_2_Domain_20 (2832, 2933)

VNGPNRCTGRVEVFHDGQWGTVCDD-SWDLRAATVVCRELGCGRAESAP
VRAHFGQGTGRIWMDDVNCVGTEDNLAQCQARPWGQ---NNCNHAEDAGVVC

ENSGT00900000140803_2_Linker_20_21 (2933, 2955)

SA------
-------ESVQVRL

PF00530 // ENSGT00900000140803_2_Domain_21 (2955, 3052)

VNGPNRCAGRVEVFHNAQWGTVCDDGWDLSDAKVVCQQLGCGTAVS
APGKAHFGQGADPIWLDDVECTGTEANFSHCILNGWGLHNCNHEEDAGVVC

ENSGT00900000140803_2_Linker_21_22 (3052, 3060)

SGDPGVRL

PF00530 // ENSGT00900000140803_2_Domain_22 (3060, 3158)

V
DGPN-RCTGRVEVLHNDVWGTVCDDGWDLREAKVVCKQLGCGTALSALPESKYGEGKGQI
WLTDVNCTGTEGSITECETKPWGENTCNHVEDASVVCS

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VGGGGRCAGR-----VEVEHGGEWGSVCLFEHD-WEA
RWAAVVCRLLGCGRVARASPYARF--------GQGTGR-------------IWLQPFFCL
---G-------TENLLEECLHFGWGRHFC---GHDRDAGVTCT-----------------
------------------------------------------------------------
---------------------------------------------------------DAV
ELRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

GGSSPCAGRVEVK-LQG---QWGSVGDDDWDMEDAEVVCQHLGCGSAS
KAYYARDTFGIGNGLVSLTQVDCRKYEATLWDCEIHGWGPYN--SSDHYWDTAVVC

ENSGT00900000140803_2_Linker_6_8 (1137, 1176)

QG--
-------FSR------------------------L

PF00530 // ENSGT00900000140803_2_Domain_8 (1176, 1347)

VGGD-GACAGR---------LEVRR
GRAWVGVCEDQVDMKA--AQVVCRELGCGEAL-----------AIPGSARFGRGSESFWD
GGFQ----------------------------------CNGTESLLS-------------
------ACARRLPLSQACAGPASVIC

ENSGT00900000140803_2_Linker_8_9 (1347, 1370)

S-------------AYTGFRLGN

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-SSSGCSGRVE
VAVRGTWGSVCASEWDLADAHVLCRHLGCGRASSVP----PGGSFGSGEGTLRPDAFGCH
GSERHPGECPVAVLGKP---PCVPGNAAAVNCSGM-------------------------
---------DDQ-LEERGDVS---------------------------------------
------------------------------------------------------------
--------------------------------------------------GMGPA-----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------LNS-----------------------
------------------------------------------------------------
-------------------------SLEEMAITCS--------------------GS---
--------------RQVRLA

PF00530 // ENSGT00900000140803_2_Domain_15 (2001, 2202)

GS----------------------------SGRCAGRVEV
YSGGSWSS---------------------VCQE----GW-----------ELQ--DAAV-
-VCRE--LGCGTAL--------------------------------------------EA
PSRARFGAGTGPLWPYVPDCSGSEES------------LWEC------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VAGVTKPLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

HGGESRCDGRLEVAIRPGVWARVSVGLWDNGTA
TVACRQLGCGVPEKIYAAPD---NG---SGPMELQELRCVGSEELLAQCNTS---GMASE
PS------K-IPEELVIAC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SGS--------------------------------------
----------------------------------------RQLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VGGPGRCAGRVEVYS
EGTWGTVCQDTWTLQDATV-VCRQLSCGW-----ALDAPGSERF----GPGTGTLWPGAG
RCSGTEDALWHCPAPV-----QPGCQRGGGA------GVVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

S------------------
------------------------------------------------------------
-------------G---SEELRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VDGGGRCAGR-----VEVKHEGEWGSVCSYDFD-WDI
RGASVVCRQLGCGTVAHASPYAPF--------GQGKGR-------------VWLHPLFCR
---G-------TETKLQNCPHFGWGKHFC---GHEWDVGVICSAGKGTECQ---------
----------------------------------DP------------------------
----L--------------------------------------AWLR-----PIPNAEAL
ELRL--E----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGGGPCEGRVEAK-LRG---RWGTVTDDAWDMDDAEVVCQQLGCGSAA
GAYLAS-RFRSVDGPIMMAFIDCHGHEAALWGCNIRGWGPYN--GP-HDYDTAVVC

ENSGT00900000140803_2_Linker_6_8 (1137, 1176)

QG--
-------FSR------------------------L

PF00530 // ENSGT00900000140803_2_Domain_8 (1176, 1347)

VGGD-SECSGR---------LEVRQ
GRAWVSVCHGHVDLMA--AQVVCRELGCGTAL-----------ALYGTGHFGAADGTFWD
GAFE----------------------------------CNGTEPLLS-------------
------ACTQRPPDIQNCTQPAAVIC

ENSGT00900000140803_2_Linker_8_9 (1347, 1368)

SCKCRGCGSVSAPRTYTGFRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1413)

AN-GDSDCTGQVE
VEAQGVWGPLCATAWDLPDAHVLCHHLGCGSAI---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------GRPSHCLL--------
-PFF--------AAALVGIQAVDRLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWY-GSRWGTVCDDGWDLQDA
AVACRELGCGGALAAPG-GAFFGEG---TGPVWLSELACQGLEERLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CTGQRAADSQH--DSTSPLDGEP--------RPGSEEPPVTH
APRPAGSPQN--GPRKKSPRPPKQAKSTRAPLLTTGAPRQDRLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHSCAGRLEVWH
GGRWGSVCDDGWDLQDAAV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCAGAEQALRDCPRSPWGRSN---CDHREDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
QDAAVACRELGCGGALAAPGAAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YATPTRP--VV
DSNSSG------------------------------------------------------
---------------TVSQAPRMPG-----SLPPAASPT-------APQEPGPD--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDLRDSAVVCRELGCRGPR
QPDPAVGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVMCTGTP
GLDTISDPFSWSWLPGLGRDRDAWLPGELATKPS----ASLTSIVPEKTTTKAPRKTPKS
TKKWVTKHAKRPTAQPPRMPTTKHSRGLGTQSPPELTSQTTTLT--------------TE
LLKRLLTEAPHRWTSHTTSKPTPQAPWTWPSGTMTTLSPQGPQEMTSETTIEK-IRQASL
EPS-----A-ETPAF--------------SPTGL---PPPGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDSWDLRDATVVCWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSETSLSDCPSGGWGKH---NCDHEEDVGFTCTGYTDDDDYPPWTWDPTSGEDLAKGATM
APGPGRALPWSS-TRHPAISS---PATRLLSVT--GDQEGYKPSGTWDT-PWGRGSA---
KRTPT---TAPTLSSGTSRPPGHPSLAPRAHGDTARAAPQ--------------------
------TRPPAPSALPGPRGLQP------TSG---------------------PASVL-P
GTSVAGPDLPSS--TTPDL----------------------------------------S
PAPTPPPTAPRE----------------LTSDPSVPPE-------------------GTP
GPNTAPYWGTAVG--------TSGSPEPSTSPHPTATTYSP-------------------
------------------------------------------------------------
------------------------------------TTPYPTITPNPTTTANPTTSPHYT
TTLQPMATPLPASTLPTTTIPL--------------------------------------
----PATT-----------------PHPTATPHPATTTR-----P-ARTADPS--STPMV
-TTKSLPTSLGPESPSS-------------------------TTMQSPVP---SPASEAS
PSRAPLTSSRGPLSTEDFRPPRSQNPTLTPGPASEPILPSDP-----------------H
SDQLPHDHPPLGPTPGQTLGPLGPCACPAA-----PVRVRACEP-PALVELVAAVRDVGG
QLQRLA------TVLEQDWQERQALGLGLAQL-----GLGQLGETV--------------
---------------------------------RRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WAPSTPVSTSTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------NALHFY---LMLL--
-LCV-------------QATEPGSIRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VNGGGRCEGRVEIYY-NGTWGTVCDDLWNMSSA
RVVCRQLHCGEPKDAKK-DAFFGSG---EESIWMDNVECDGSENALNDCN-FR--GWGLH
DC------S-HNEDAGVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SDQP-------------------------------------
----------------------------------------FKIRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 738)

VDGNSSCKGRLEVNH
NGTWGTVCNDQWDKKDAKV-VCKQLQCGP-----PKFSYECNIHKPITTETEALMLQQYT
QCTVREDVLQFCLILDL-CFR---CSHSKDT------GVIH-------------------
------------------------------------------------------------
-----------------

ENSGT00900000140803_2_Linker_3_4 (738, 744)

SLNIRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VDGNSSCKGR-----LEVNHNGTWGTVCN--DQ-WDK
KDAKVVCKQLQCGPPKFSYECQPF--------GEGSGP-------------IWLDEVHCT
---G-------KEYSLSECRFSAPGVHDC---EHREDVSVMCR-----------------
------------------------------------------------------------
---------------------------------------------------------EPF
KIQL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGSNRCAGRLEVF-YDG---EWGSVCDDDWDTLDSQVVCNQLRCGDPQ
LNRERGPRFGQASGRIWLDDVQCNGYESSLEECKHRTWSYH---DCTHKEDVSVYCTDSS
GDI---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLLVELSPSTEEPPVTH
GPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTSREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSAPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKYAKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTAE
FTRRPTTEAPRRWTSHTTATLTPQAPRERTTKTTAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
ARVPGHTLPWGT-TRRTGISS---PATRRLPDT--GGKDGYKLPWTWDT-PSGRGLA---
EGTPTAGKLGPTLGAGTTRSPGSP-PTPRIHGDTGSPRKP-----WPERRPPR--PAAT-
RTA-PATPSPGPSASPGPPGPAL---T---SDCSPELTP-HPAL--TPEATSDPPDTSPP
-----TPDPTSR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PSPMPLPTLPKE----------------LTSDPSTPLEVTSLSPTSEQ-IPE---SDTTP
DLDTTPYSSTVSE--------YSRSPAPSPSPHPTTIPDPT------MTP------DYTT
TPNPTVTPQFPTTTHPTTTPQ-------PTTITYSTMIPDPTTTPQPFTTMQPTTTP---
---------------------------HP-------------------------TTPHPT
TTP---------------------------------------------------------
----PTTT-----------------PHPTTTPHPTTTPH-----P-TTTPDSS--ATPII
-TTKSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQMPTLEP---SPALESS
ASRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTRTPHSASDLTMSP----DPHLSLIAHP
LDHPRLDPLTLGPTPDQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRVVEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MAPLF-NLMLAIS
AIFIGSCLS----------ESPPKVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGPHRCEGRVEVEL-NGQWGTVCDDGWDLKDV
AVVCRELNCGAARKTPR-GAKYKPAAPKEQKVLIQDVNCNGMEGTLSECEQN---EDVF-
NC------P-HEEDAGVQCED---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFT----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

DGPGHCRGRVEVL-HQA---QWSSVCKAGWNLRASKVACRQLGCGRAL
LTHRCCNKMAQGKGPIWKGQMSCSGHEANLRDCPFKPLE-N---NCTHSEDTWMECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDNPCSGRLE
VLHMGTWGSVCDDGWGEKEDQVVCKQLSCGKPL--FPSFKARKSYGPGAGRIWLDDVVCS
GEEQSLESCRHRLWGYH---DCTHKEDVAVICSDFDV-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MDCMISLNFLLLSPA--
-IYTGPGIL----------GSFSRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGDHRCEGRVELQQ-DDEWVTVCDDYWNMDSV
AVLCRELGCGAARKTMS-GTVYGPVTPKDQKVFIHLFRCNGIEESLSQCERE----DAI-
GC------S-HDEDAGAVCEG---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------PE
SVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGRCQGRVEVK-FQG---EWSSVCQAGWSFAAAKVVCRQLGCGRAT
LTRRGCNKATQGQGAIWQRKASCSGQEVSLQDCLSEVWEH----NCTHNEDVWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFALKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GRSHCEGRLE
VLHKGEWGSVCDDGWGQDADRVVCRQLGCGQPL--SPPVKVRRRFGPGVGRIWLDDVKCS
GKEPSLEQCLHRSWGYH---NCNHREDVAVVCEEQQSGLPD-------------------
-----------------A------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

MRVLACLLAALMGIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
------------XXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXPAPRLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

ADGPHGCAGRLEVWH-AGVWGTVCDDGWDLRDA
TVACRALGCGGALAAPG-GAFFGEG---PGPILLDNVRCRGNETALSFCPAR---PWGQH
DC------H-HREDAGAVCDXX--------------------------------------
---------------------------------------XXXXXXXXXXXXXXXXXXXXX
XX----------------------------------------------------XXX---
------------------XXX---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------XXXXXXXXXXXX--XXXX---XXXXXXXXXXXX----------------
------------------------------------------------------------
----------------------------------------------------------SP
RLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSRCSGRLEVW-HSG---RWGTVCDDAWDLRDAAVACRELGCGAAG
PQDPAMGRFGWGSGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVEVTCTGTP
GLDDLSDPLSWSWNPD------AWLPVELVTKHPVRL---TTSVTMEKPTSSILGKMPKS
TRKWARKGAKWP-------------TTKGPQGHPELTSQA---ISPTTEA----------
--------LS-RLPSNTS---AAQTPWD--------LTTQDPQDMT-SGGTTQHSPLTSV
GASPP-------------------SSKDP-SPTGNPVEDSGLFRIRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

AD-GPNRCAGRLE
VRRAGRWGTVCDDGWDLRDATVVCRELGCGRVR--PR--VGKTHYGPGTGPIWLDDVGCR
GAEDSLSHCMARPWGQH---NCDHEEDVGLTCTXXXXXXXX-------------------
-----------------XXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
-X-XXX--------XXXXXXXXXX----X--XXXXXXXXXX----------X----XXXX
XXXX------------------X------X------XX----------XXXXXXXXX---
-XXXXXXXXXXX------XXXXX--------ASGSGQRKPERRTPRPAAHGAATP-----
-------TASPAPATG--------------------------------------------
----------------PAPPEPSSTPHTAAAPKATSSRGLT---LPAV------------
--------------------------------------------------------SREL
---------------------AS---DPSMPMTVP--------------------GRTPT
SA----------LSPEPRATQH----------------------------PTMLPXXXXX
XXXXXXXX---------------------XXXX----XXXXX--XXXXXXXXXXXXXXXX
XXXXX--XXXXXXXXXXXXX---------------------------------XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXHGS------------LTAPPSQPPPS---------RP
L---Q--PP-----PEQNTAPTGPCVAPEPPL-----RVMACEP-AALVELVAAVREVGA
QLQRL------TGVLERDQQ----------------------------------------
----ERQAQR-------WLS--QLLEAAQGLGQ-----------------LGE-------
-------------------A-MRELAGGA-------------------------------
------------------------------------------------------------
--------------------WHARTASPPTAI-LEEEEERPLRGD------V--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRGL--------
-ACL--------LAMLVGIQAIERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-SGRWGTVCDDGWDLRDA
EVACRVLGCGGALAAPG-GAFFGEG---TGPVWLSELNCRGNEGQLGICPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CVGQRAANSRE--DSMSLLDGDSWLALSGELSPSSEEPPITH
APQPAASSQN--GPRKKNPRPPKQTKSTRAPVLTNGAPHQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGEGPVWMDDV
GCGGGEEALRDCPRSPWGRSN---CDHTEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------SAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGTGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-DVQPTVP--AV
DSNSTTR-----R-PLST------------------------------------------
---------------SVGQMPGPAG-----TWPPPASPT-------APPEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDVRDSAVVCRELGCGRPR
QPDPAAGRFGWGAGPIWLDDVGCMGTEASLSECPAASWGKH---NCAHNEDVGVTCTGTP
GLDTISDPFSWSWLPGLGRDQDAWLPGELTTK------ASLTSSVPQKP-TKAPGKAPKS
TKKWVTKNAKRPTTQPPGMPTTKHSRAPGTPTSLHPTAR------------------TSE
LPKRLTTEAPHRQTSHTTVRLTPRAPWEWTSEPVLSRSTQGPQEVTSEATTTE-NPQTSL
EPS-----G-EST-EGSLESSQD---PAATPTAGVPV-SSGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGLWGTVCDDSWDIRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEMSLSDCPSGAWGKH---NCDHEEDVVLTCTGYTGDDDYPSWTWDPTSGEDLTKGTTE
AARPGHSLSWAT-TTNTEVLS---PATQSLPDT--DDQGGYEFSWTWDT-PSGRGLS---
KGTPTTTKPGSTVTTSTSKSPGHPFPVPRARADTGSPRKP-----TPERRPL---PTSA-
RIV-HTTSSPASSTSPEPS------GSRQTSGSWPQLIP-DA----KQEGTSSPPKPSPL
-----TPGLPSP--------------------ATFA-------LSTPNTSLLP--ARSPE
LSGSPAPTSPEG----------------LASDSSMLSEVSRLSPTSEP-TPG---SDTTP
----AP--EVIPG--------SSDSSDLPMNTRTPTQPS--------------------T
A-------------------------SHPTS-----------------------------
------------------------------------------------------------
-------------APQPTTNPQQPGNSHPATS----------------------------
-------------------------------PQPPTNTH-----P-----STS--TPATP
-TSESLPSSRKTGFSSPT-----KPSLNPELTFE-EAPSTDTSQMQSPEL---FLASESG
PSRPSPASNLDPLSTDAFQPPRSQT----------LHSASDPMVTP----DLPISSVAHP
SDQPSPDHLTQGPTPNHNPDPFGPCVSPVP-----PVRVMACEP-PALVELVGAVREVGH
QLQRLT------WALEQDRQERQVLALGLAQLVEAAQGLGQLSETV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPVPMTTTTEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------PHPL--------
-PSL--------PAALVGIQAVGKCPDSSH------------------------------
------------------------------------LPPSTQRQDSPFCPSQ---AWPHP
HWVPGPPEF-HSSVPASPAAGQRVANSRD--DSTSPLDGAPWPGLSVELSPSTEEPPVTH
GPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQGKL-----PA

PF00530 // ENSGT00900000140803_2_Domain_3 (531, 641)

GCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVCTGTSGVGNIF---------
------------------------------------------------------------
------------------------DGH--SWGR-----GCSWHPGVGGQGCC--STSRSA
QDAPAAQNN-------PAPNGNIA--------EDEPQP-------------CGSPGWPCL
LAPGGRQPSTLHKVTSRFSL----PDGVC---G-WQSLIPCSTGMPLG-YVPPTAP---T
DSNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKYAKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT--ALTTEAS---RRPTAE
FTRRPTTEAPRRWTSHTTATLTPQAPRERTTKTTAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSASTTK-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
ARVPGHTLPWGT-TRRTGISS---PATRRLPDT--EPEAGALRGDASRS-RTARVAA---
--PP--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTGPGLLDAQPSSHRFGGPLSRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGDHRCEGRVEVQR-ANEWGTVCDDGWDESDA
AVVCRELGCGAVKKAIS-GTAFGPLTQEDQKIFVQEFRCNGLEESLSQCERE----DFF-
DC------S-HKEDAGAVCGF---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPQRCQGRVEVK-HQG---QWGTVCKASWSFAATKVVCRQLGCGRAL
LTRKCCNKATQGQGPIWLRKASCSGKESSLEECPAGAWERS---NCTHDDDMWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1472)

VG-GDGRCAGRLQ
VLHKSQWGTVCDDGWGEAADRVVCRQLGCGPSL--SPPAKSRRRFGPGTGRIWLDDVACS
GKERSLEECPHRFWGRH---NCNHAEDVAVVCAEQ-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------L---------ERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLSVELSPSTEEPPVTH
GPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MMSQALGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKYAKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTAE
FTRRPTTEAPRRWTSHTTATLTPQAPRERTTKTTAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGTRAWRRWRRLRGVV------------
--------------RRMESS-----CSRRFQ-K--GREEQQQGPL--RK-RMGSTIA---
PISPKATQT----MMIIPPGPGTP-PQQRTWFHSPPKGKP-----WPERRPPR--PAAT-
RTA-PATPSPGPSASPGPPGPAL---T---SDCSPELTP-HSAL--TPEATSDPPDTSPP
-----TPDPTSR--TNPYL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PSPTPLPTLPKE----------------LTSDPSTASEVTSLSPPSEQ-IPE---SDTTP
DLDTTPYSSTIPT--------HHN------------------------------------
------------------------------------------------------------
--------------------------------------PHP-------------------
------------------------------TTPYPTTTPHPTTTPHPTTTPHPIT--T--
--PDPTTT-----------------PHPTTTPDPTTTPH-----P-TTTPDSS--STPII
-TTKSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQMPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTMSP----DPHLSLIAHP
LDHPPLDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRVVEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAMLVGIQAIERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWY-SGRWGTVCDDGWDLRDA
AVACRVLGCGGALAAPG-GAFFGEG---TGPVWLSELACRGSEGQLGICPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CVGQRAANSRE--DSVSLLDGDPWLALSGELSPSSEEPPITH
APQPAASSQN--GPRKKNPRPPKQVKSTRAPVLTNGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGEGPVWMDDV
GCGGGEEALRDCPRSPWGRSN---CDHTEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLGGDVQPTAP--AV
DSNRTTP-----R-LQST------------------------------------------
---------------SVGHTPGPAG-----SWPPPASPT-------APPEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HDG---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVGCVGTEASLSECPAASWGKH---NCAHNEDVGVTCTGTP
GLDTISDPFSWSWLPGLGRDQDAWLPGELATKPS----ASLTSSVLQKT-TKAPGKVPKS
TKKWVTKNAKRPTTQPPGIPITKRPRVPGTPTSLSPTPR------------------TSE
LPKRLTAEAPRRQTSHTTERLTPRVPWEWTSETAASLSTQGPQEVTSEATTAQ-TPQTSL
EPF-----G-ENP-EGSLESSQD---PAATPTAGVPV-PSGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGLWGTVCDDSWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSETSLSDCPSGTWGKH---NCDHEEDVVLTCTGYTGDDDYPSWTWDPTSEEDLTKRTTV
ATQPGHTPSWAT-TTNPEVLS---PATQSLPDI--DDQGSYELSWTWDT-PSGRSLS---
KGTPTTTKPGSTVTTSTRKSPGHPFPAPRARANTGLPRKP-----KPERRTLQ--PTSA-
RTT-HTTSSPASYTSPEPSG------SQQTSGSWPQLFP-DLAS--KQEGTSTPPKTSPL
-----TPGLPSP--------------------TNFA-------LSTTDASLLP--TRPPE
LSGSPTSNSPEG----------------LTSDSPMLLEVSSLSPTSEL-TPG---SDMTP
DLGTAP--KIIPE--------SSESSDLPTSPSTHTQPF--------------------T
ASYPTSIPHPTTIPHPTTTPH-PRAPSHPTTIPQ--------------------------
------------------------------------------------------------
----LNTTSYPTMALQPTTNPQHPGSPHPTTS----------------------------
-------------------------------PQPPTNTH-----S-----SST--S--AT
-PTKSLPSSPETEFSSPTPQPRVKPSLHPDLTFV-GVPPTGKSQMQNLEF---SLASESG
PSRPSPAPSMDPLSTEVFKPPRSQT----------LHSVSEPMVTA----DLAISSMAHP
SDQPPPDRLAQGPTSNHNPGPFGPCVSSVP-----PVRVMACEP-PALVELVAAVREVGD
QLQRLT------RVLEQDRQERQVLGLGLVKLVEAAQGLGQLSETV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPVPTTTTTEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------WVALQI-LL-----
-----ILFL----------FSPPRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEVER-NGQWGTVCDDGWDLQDV
TVVCRELGCGAAKKSPT-GTQYGPLAQKDQSVLTQNVNCNGMEDTLAQCEQD---EDVF-
NC------A-HEEDAGASCENP--------------------------------------
---------------------------------------D--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------I----------------
------------------------------------------------------------
----------------------------------------------------------PD
RVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

SGSGHCMGRVEVE-HKG---QWSTVCKTGWNLQAAKVLCRQLGCGKAL
VAQRHCNETTQGQRSIWMSKMACLGQEATLQNCDSGPLKRN---SCTHHDDTWVECEG--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1468)

VG-GDKFCSGRLE
VLHKNEWGTVCDDSWGEQEDQVVCKQLGCGKPL--VSSSRTRKRYGPGAGLIWLDDVHCS
GKEESLYQCKHRLWGYH---DCVHKEDVSDFDLAHIHVEYV-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MDLL-FLIFA--
-ICTGPVLL----------GSSSRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGPHHCEGRVEVEQ-EGQWGTVCDDGWDIKDV
AVVCQELGCGVANGTPS-GVSYKPLAEKEQKIFMQEVKCNGMEATLFHCERA---EDVF-
DC------S-HNEDAGALCEFS--------------------------------------
---------------------------------------TV-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-GGPGRCKGRVEVN-HQG---QWGTVCNAGWNLSAAKVVCQELGCGRAI
QTRRCCNKATQGQGTIWLTQVSCSGKEVSLWDCPSGHWGKN---NCTHEEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDIRCSGRLE
VLHEGIWGSVCDDGWGKKEDQVVCKQLGCGESL--SPSVKARRSFGPGVGRIWLDDVHCS
GKEQSLEQCQHRFWGYH---NCNHKEDVAVICSEQ-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGHEGQLGFCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSASPLDGAPWPGLSMELGPSTEETPVTH
APRPAGNPQN--TSRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDATV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGLWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-FVPPTVP--TV
PSNDSIPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----ISPPLASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGHFGWGAGPIWLDDVGCVGTESSLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRNAWLPGELATKPS----ASVTASVLEKTTMKAPGKMPKS
TKKWVTKNAKRPTTQPPVTPTTKHSRAQ---SPPDLTSQTTA-A-LTTEAS---RRPTFE
FTRRPTTEAPHRWASHSTAMLTPQAPREQTSKTMVMLTTQSPREMTSEAIIKR-IPQASL
EPS-----A-EIP-QE---SSKD---PAPSPTASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGHWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGEWGKH---NCDHEEDVVLTCTGYADYDDYPPWTWDPTSAEDLAKGTTT
VGGPGRTLPWGT-TRHPGTPF---PATRRLPDT--GGKDGYKLPWMWDT-ASGRGLA---
EGTPTLGKLGPTVGAGITRSPGSP-PTPRVRGDTGFPRKP-----WPERRPPR--PTAI-
RTA-PSTPSPGPSASPGRPGPAL---T---SDSSLELTP-RSAL--TPEATSDPADTS-P
-----TSDPASR--TNPDF---------DLTSPDFA-------LSTPDSSVVP--PLTPE
LSPTPPPTLLEE----------------LTSDPSTPLEVTSLSPASER-TPE---SDTTS
DLDTTPYPSTVSE--------YSRSPDPSPSPHSTITPDPTTT------P------HPTL
TSHPTMTPHFPTTTHPTTTPQ-------PTTIIHSTMIPDPTTTPQPFATMLPTTTPQ--
------------------------------------------------------------
----PTTTTHSTTTPDPTTTP------------------------QPTTTMQPTT--T--
--PQPTTT-----------------MQPTTTPQPTTTPH-----P-TTTPDPS--STPII
-TTKSVPTSVGTELSSPTPAPTVKPSLHPELTFTAPAPHPSTSQMPTLEP---SPALESS
SSRSSTATSIDPLSTEDFKPSRSQSPSLTPPPTHAPHSASDLTVPP----DPRLSPIAHP
LDQPPLDHLTLGPTPGQSPVPHGPCVAPAP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRLAEVT--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPVMPVPTTTTPEA--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------PYSS--------
-TPL--------PAALMGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGSEGQLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRDGDDPPSILEGDPWPGLSGELSPGSEEPPGTH
APRPAGTPQN--SSRKKGPRPPKQAKSTRAPQLTAGAPRHERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCSGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGTVCD--DA-WDL
RDASVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRLCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPRWNP--KR
ELDGFLT-----------------------------------------------------
--------------------------------------P-------ILW-VSSI--LGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSRCSGRLEVW-HAG---RWGTVCDDSWDLRDAAVVCRELGCGGAR
QPDPAAGRFGWGAGPIWLDDVGCLGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTETP
GLDSISDPFSWSWIPGLGRDPDAWLPGELATKPS----ARLTPSVPEKTTTKAPGKMPKS
TKKWVTKNAKRPTTQPPVMPTTKHSRVLGTQRPLELTSRATT-T-LTTEAS---HRPVSE
STAKLTTGVPHGMTSHTTATRTPRAPRERTSKAVATSTTQGPREVTSEATATR-IPLTPK
ESS-----A-EIPAQGSPESPKD---PAPSPTGSTTR-GSGEPVPRASA-G---------
-----LWKGPG--------------PSGQNPLRPRD----GR-----GAHLHWA------
----GLNPCP-------------------TFSQGYADEDDYPPWTWDPTSGEDLAKGTTA
AGVPGHMLSWGT-TKSPGGPS---PATRRLPHT--GEGHGQGAEGAII------DLC---
--------------VGRTDL-----GPSVFPTPPGSERKL-----WPQRRLLR--PTSS-
RTV-PPAPSPDPSASSEPPGSPV---TSVTSNPAPWFIP-EAAS--TRKVTSDPPDTLPP
-----SPDLASW--TSSDL---------TLTTPGLT-------LSTPDATVIA--ASPSD
LSPTPPPTLPKE----------------LTSDPSAPEVVTHLFSTSEL-TTE---SVTIP
NLDTAPYPNSVPD--------HSRSPDPSTSPYPTTTPHSALTSHPSTSTTS----QPTT
TFPPTTTPHSTATPHSTTTPH-------PTTT------PQPVTPPQPTTP----------
--------------------------------------SQPTTTPQPTTPLYLTTTPHPT
TTLHPTTTPYPTTTPQSTTPPHS-------------------TTAQPTTTPHPITTSYPA
TT-----------------------PDSTMTPHSTTSTH-----P-TMTADPT--STPVV
-TVKSILTSLGTEFS-PTPAPAVKPSLHPWLTSMGAA---HLSQMSSLAP---FPASESS
HPRSSPGPSMDTLSTEDFQPPRSQSPKPTPPPTQTPHSASDPTGTS----DLHLSSIVHP
LDQPPPDHFTLRPTPGQDPGPVGPCVTPAP-----PVKVMACEP-PALVELVAAVRDVSG
QLQRLT------QVLKQDQQQRQALELGLTQLVEATRGLGQLGEVV--------------
---------------------------------KRLAERA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------L---FPLCLVM------GSSVAES----------------
------------------------------------------------------------
-------------D---HMEIRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VGGPNLCSGR-----VEVFLSGQWASVCD--DS-WSI
EEAMVVCRQLGCGSAVSATHEAQF--------GNGTVS-------------IGLDDVRWR
---G-------TESALSECPASPWGEHDC---SHEETAGVICSDLVYKCTLAKE-TG--Q
------------------------------------------------------------
----------------------------------------PWGSD----------PTHPT
EIRL----------VD

PF00530 // ENSGT00900000140803_2_Domain_6 (1037, 1137)

NCSGRVELL-HHG---EWGTICGDGWGIEEATVVCHEMGCGTGS
M-NQSRTWNGSGTSPIWLDGVHCRGTESSLFQCSTSPLGRH---GCDSGRTAFVVCSVPF
PPPVP--C----------------------------------------------------
----------E-------------------------------------------------
------------------------------------------------------------
------------W-----QTSINS---AK--------ACSSSLTACFTY

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPTPCTGRVE
VFHNKAWGTVCDNGWDLEDASVVCQEVGCGEALVAA----IGARFGQGSGSIWMDEVNCT
GKEKVLKKCPQEKSLSL---ICDHRKDVGVE

ENSGT00900000140803_2_Linker_9_11 (1472, 1518)

CAGNREP---------SVPSPLSQQNSEK
PVSCRYKWSILM-MRLA

PF00530 // ENSGT00900000140803_2_Domain_11 (1518, 1734)

DGRH---RCTGRVELFL-DGQWRMVSYRRWD-LKEPWVVCR--
-H-LGC--------EAAPHPLMYP------------------------------------
------------------------------------IY----------GEKTPSIWM---
-DGVQCTGTETS------FSECE--------ITPWQDSDLDRLLPFYVVGVTCT------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------GKS--------------------LS---
--------------SELRL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2236)

VNG----------------------------SNYCSGRIEV
FHNEMWGT---------------------ICDA----GW-----------DLQ--DAQV-
-VCRE--LGCGEAL--------------------------------------------SA
SGGAQFGRGAGPIWLEGMSCTGTEES------------LRQCPKGQWGE-----------
H---SCDHSRDASVECAE-----------------------------ASCYFCYLPLCLT
HDNLI--SPS--------------------------------------------------
-------------------------------------------------------PWKTS
K-----------------------------------------------------------
------------------------------------------------------------
-----------------------------------SLELRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2638)

VNGPNICSGHLEVLYNQQW
GTVCDIGWDTHDAQVVCRELNCGDASKGFEGVRYGQGSGLIWLENVNCTGEEMSLTDCP-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------LSPP--------
-NSL--------AAALVGIQAIERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWY-NGRWGTVCDDGWDLRDA
AVACRVLGCGGALAAPG-GAFFGEG---SGPVWLSELACRGNEGHLGLCPHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGTAQFLTWS--------------------------CVPFP
APRQAATPQN--ASRKKNPRPPKQAKSTRAPVLGSGGPRQERMRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 642)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDATV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHTEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

SG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGSRWGSVCD--DA-WDL
RDAAVACRELGCGRALAAPGGAFF--------GEGAGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVLPTAP--AV
DSNSSTPREVASR-PLST------------------------------------------
---------------TVGQTPGPRV-----SWPPPASPT-------APPEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPNRCSGRLEVW-HNG---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QSDPVAGRFGWGAGPIWLDDVGCVGTEASLSDCPAASWGKH---NCAHNEDVGVICIGTP
GLDTISDPFSWSWLPGLGRDQDAWLPEELATKPS----ASHTPGVLEKT-TKAPGKVQKS
TKKWVTKNTRRPTTQPPGMPTTKRTRVPGTLNPPNPTSRT------------------SE
LPKRLTTEAPHRRTSHTTSKQTPQAPWEWTSETVATAATQR--------------PQTSL
EPY-----P-ESP-EGSLESSKD---PAPTPTTGIPV-ESGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPDRCAGRLE
VWHAGRWGTVCDDSWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSETSLSDCPSGTWGKH---NCDHEEDVGLTCTGYTDDDDYPTWTWDPISGEELAKGTTV
PAQSGHTLSIGT-IRHPEFSS---TATQSRPDT--GDQGRYKISWTWDT-PSGRGLS---
KGTPTTTRPGTTITTGTPKIPDHPSAAPRAHWDPGELTSD--------------------
-----------------------------------------TAS--KPEVTTGPPDASPA
-----TPGLTP------------------LMTSDLA-------LSTPDVTLLP--ALAPE
HSPSPPSTSPQG----------------LTSDSSALTEGTSLFPTSEV-TPG---SDTTP
DLGTTPPPHTEPE--------GSESSDLPTNPTITTHP----------------------
----------TSPPHPTT-------------TPHPTTIPHPTIDPQPPIT----------
------------------------------------------------------------
--------------------------H---------------------------------
------------------------------------------------------------
-----------HKLSSPPPAVRGK-----------PTPHTITSHVQNLEP---SPASDSD
PSKPSPAPSMDPPFTEDFKPFSSQSP-----SAQTPHSASDPTVNP----DLHLSSMVHP
LDQPSPDHHTLGPSPDHIPGPLGPCVSPTP-----PVRVMACEP-PILVELVAAVREVGD
QLQRLT------QVLEQDRQERQALGLGLVRLVEAAQGLGQLGETV--------------
---------------------------------KRL---A--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPMPTITTT-E--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MA-LL-FLILA--
-IFTGPGLS----------ESSPRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGPHRCEGRVEVER-MGHWGTVCDDGWDMNDV
NVLCWELGCGAAKGTPS-GSVFKPSAGNEQRVLIQLVNCKGMEKTLSQCEYE---EDVF-
DC------S-HKEDAGASCENP--------------------------------------
---------------------------------------DSPS-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
SIRL--V----

PF00530 // ENSGT00900000140803_2_Domain_7 (1032, 1074)

-DGPGRCKGRVEIQ-HQG---QWSTVCKKGWNLKAAKVVCRQL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVRQ-NGQWGTVCDDGWDIKDV
AVVCRELGCGAANGTPS-GILYEPPAENEQKVFIQEVSCTGTEDTLAQCEQ----EEAY-
NC------L-HNEDAGALCENP--------------------------------------
---------------------------------------ESPL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
NVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---RWYSVCQTGWSLRAAKVVCRQLGCGRAV
RTQKRCKKLAQVQRSIWLSQMSCSGREATLRDCPSGPWGKS---TCIHDEDTWVKCED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDKLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFKDRKSYGPGVGRIWLDDVRCL
GEEQSLEQCQHRFWGYH---DCTHQEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------X--------
-ACL--------LAALMGIQAVERLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VSGPHACAGRLEVWH-AGRWGSVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---EGPVWLSELACRGGEARLGLCAHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 526)

CAGQRGAGARD--DATSLEAGGPWL--PGGLDPITEAPPGTH
APRLGGGPQN--GSRKKGPRPPKQAKSTRAPSLVTGAPRHGRLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 641)

VSGPHACAGRLEVWH
AGRWGSVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GAGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CAG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 844)

DGPHGCAGR-----LEVWHAGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
GNET-------GGPSLGPCLGRGLKSARQ---AAGQGAGSGLGSMPLG-YVPPTAP--AV
GGNSSSPTEVASR-PAPT------------------------------------------
---------------AVTPRPQTAG-----SSPPPGSPT-------ARLELGPE--AGSP
HLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSRCSGRLEVW-HDG---RWGTVCDDSWDPRDSAVVCRELGCGGPR
RPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVACTGSP
GLDSIPDPFSWSWIPGLGSDRDAWLPGELATKPP----ARLTPSVPAKTTTKAPGKIPKS
TKKWVTKHTKRPTPQPPVMPTTKFSRGPGPQRPPGFTSSTTT--TLTTEAP---RRPTSE
FTTRLTTEDPHRLTSRTPATPTPQAPREKTSAT---LTTEASQEATSEATRTR-IPQASL
EPG-----T-KIPAGGSSGPSRD---SAPSPTGAMTGESAGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDLACK
GGEASLSDCPAGPWGKH---NCDHEEDVGLTCTGYTDADDYPPWTWDPTSGEDLAKGTKA
TGVPGRTTR------SPRTH---PPTARHLPDT--GDKDSDKLSWTWDT-PLGGDLD---
KGTPVTGTPGRTSTTGTTRSPGHPSSAPRTHGDTGGTENQTWDLPWGKEAPNHHSPTAGF
KTQTPSREGVPPMTSVLPPRH---------ADILGWLIP-RVGP--FSASQGIKQHSWPL
PLDARSSPLSDW--TTKNV---------SP--QGLS-------K--------------SK
CCPTPPMGKPHQLPPGPP-APTPVSPVLSTHGPLNLLSLNHSFPYASHTAPAESEPGRVP
VLGA---PSGSPE--------RNRAVDQFQGRWTCGVEESRVGSRGSTS---------EL
HLLP-IRLNFSTLPHPRLTPPSPADHILPGPSPQSRTLPHPPSGTPPPPP----------
-------------------------------------------------------SPH--
-----------SRTPQPRAAEDASVTPRGSAPLHWPA--------------QPRVSARGA
GHTDLSL---------------------SVFPPPPG------------------------
-SVRSPWPERGAPSASPGPGPTQTPTARPASLK--CPTQLPGXRCSARSP---LQSRGSS
PSKPSPATGMDPLSHEGFKAPRSQSPKTTPL-IPEPHFTSDPTVAP----DIH---IAHT
LDQLPPDRLTPGPTAGESPVPLGPCVAPSP-----PVRVMACEP-PAMVELVAAVRDVGA
QLQKLT------RALEQDQQERHALGLGLTQLVQAAQGLGQLGETV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WAPSTPVPT--TPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------FA----------GSSSRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGSTRRCEGRVEVEK-EGHWGAVCDDGWDIKDV
AVVCRELGCGEARGTPS-GILYKPSSEEERKFLIQDVDCNGMEDTLFQCE-L---EDVF-
NC------L-DNEAAGALCESE--------------------------------------
---------------------------------------DDLAK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------YI----------------
------------------------------------------------------------
----------------------------------------------------------PE
SVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

GGTGACNGRVEVK-HQG---QWGTVCKTGWSLLDAKVVCRQLGCGRAI
LTKRSCNKATEGQGPIWLSHVSCSGQEVSLQDCPSEPWGMN---NCTHDEDMWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFKLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GNNSCSGRLE
VLHKGKWGSVCDDGWGEKEDRVVCKQLECGQSL--FPSVKVRRRFGPGNGTIWLDDVHCS
GEEYSLEECGHRLWGYH---NCKHKEDVAVICS---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------TETPEADQPDIRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VNGSSRCSGRVEVLH-NGVWGTVCDDSWGMEEA
RVVCRQLGCATAVTAPR-NGYFGKG---DGRIWLDELRCTGTESALSQCP-SR--PWGEN
DC------H-HGEDAGVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

SGRG-------------------------------------
---------------------------------------SMEVRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

MGGSTPCTGRIEILH
NQRWGTVCDNGWDLNDAHV-VCREVGCGA-----ALAATTAAKF----GQGSGPVWMDQV
NCTGEEDTLRKCPPKILAEHR---CDHNKDA------GVEC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

TE-----------------
------------------------------------------------------------
-----------------PPEIRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 882)

TNGPSKCSGR-----VEILHEKLWGTICD--DD-WDL
EDAQVVCQYLGCGTALSAPRGSRF--------GQGTGP-------------IWLDGVNCT
---G-------TEKAISKCPAKEWGQHDC---THSEDAGVTCAVF---------------
------------------------------------------------------------
---------------------------------------------------------ISS
ELRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-GGLNRCSGRVEVY-HNQ---QWGTICDSNWDLNDAQVVCRELDCGSAT
K-ATGGSRFGQGSDIIWLDQVNCTGKEAFLSECQKRPWGQH---SCSHRGEASVECSD--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PNEVRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GTSRCTGRVE
VLHNQQWGTVCDDGWDLTSAQVVCRELGCGVALSAP----RGASFGRGADPIWLDDVKCK
GTEAALRDCRLKAWGEH---NCNHGEDAGAVC

ENSGT00900000140803_2_Linker_9_11 (1473, 1518)

SV--------------------------
---------YTE-LRLA

PF00530 // ENSGT00900000140803_2_Domain_11 (1518, 1733)

NGTS---RCSGRVEIFY-NQQWGTVCDDRWG-SKQAEVVCR--
-E-LGC--------GVPLKAHTKA------------------------------------
------------------------------------FY----------GQGTGPIWL---
-DDVNCQGTETS------LKDCS--------ASSWGHNN---CNHGEDAGVECAGNL---
FY----YSLPSEPLLGLNR-------------LKQRL-----------------------
-------------------------PK---------------------------------
---------------------------------------------------------ANI
--------------------------LPCLAPIIS--------------------DP---
--------------VELRL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2237)

VNG----------------------------SHRCAGRVEV
FHLHQYGT---------------------VCDD----SW-----------DIN--EAVV-
-VCRY--LGCGTAI--------------------------------------------SA
PRGARFGRGADPIWMDDVECTGTETS------------LSSCTAKPWGS-----------
N---DCNHGEDAGVIC

ENSGT00900000140803_2_Linker_15_16 (2237, 2272)

SA---------------------------FENVRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VNGSNRCSG
RVEIRSPHNDQWGTIYDRTW----------DLTAASILCGQLGCGV-------ASSAPGG
AHFGPGSGSV-------CFD--DISCKGTEDTLHECNINFQGTNN---CNHRHDAGVICS
G-----------------------------------------------------------
------------------------------------------------------------
-------------------------------------NIRLQ

PF00530 // ENSGT00900000140803_2_Domain_18 (2563, 2662)

DGPHSCAGRLEVFHQQQW
GTVCDDGWGLPDATVVCRQLGCGIALEAPHGAHFGRGLGSIVLDDVNCTGSEKALKECGG
RTVGEHD---CDHAEDASVVCSGNSFKVSHRCTILNPNLKIAAVILGVL-------AIIV
IIVGVLFYMRKKRAQRMS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGLHRCEGRVEVEQ-KGQWGTVCDDGWDIKDV
AVLCRELGCGAASGTPS-GILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQ----EEVY-
DC------S-HDEDAGASCENP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
GVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---QWYTVCQTGWSLRAAKVVCRQLGCGRAV
LTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKN---TCNHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GDNLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFRDRKCYGPGVGRIWLDNVRCS
GEEQSLEQCQHRFWGFH---DCTHQEDVAVICSG--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVDRLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGHEGQLSLCHHR---GWKAH
IC------S-HEEDAGIV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSASPLDGAPWPGLSVELGPSTEETPVTH
APRPAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDATV-ACRELGCGG-----ALAAPGGARF----GPGSGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHRGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGAGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTVP--TV
TSNDSIPREAASR-PPST------------------------------------------
---------------MTNQAPGTAG-----VSPPLASPT-------VPWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGHFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRNAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKNAKRPTTQPPVTPTTKHSRAQ---SPPDLTSQMTA-A-LTTEAS---RRPTFE
FTRRLTTEAPHRRTSHSTAMLTPQAPRERTSKTMVMLTTQSPREMTSEA-IKR-IPQASL
ELS-----A-EIP-QGSPESSKD---PAPSPTASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGHWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLRDCPSGEWGKH---NCDHEEDVVLTCTGYADYDDYPPWTWDPTSAEDLTKGTIT
VGGPGHTLPWGT-TRHPGTPF---PATRRLPDT--GGKDGYKLPWMWDT-ASGRGLT---
EGTPALGKLGPTVGAGITRSPGSP-PTPRVRGDTGSPRKP-----WPERRPPR--PTAI-
RTA-PPTPSTGPSASPGPPGPAL---T---SDSSLELTP-RSAV--TPEATSDPADTS-P
-----TSDPASR--TNPDL---------VLTSPGFA-------LSTPDSSVVP--RLTPE
LSPAAPPTLLKE----------------LTSDPSTPLEVTSLSPTSER-TPE---SDTAS
DLDTTPYPSTVSE--------YSRSPDPSPSPHSTITHDPTMTP-DPTTP------LPTL
TSHPTMAPHFPTTTHPTTTPQ-------PTTIIHSTMIPDPTTTPQPFTTMQPTTTPQ--
------------------------------------------------------------
----PFTTM------QPTTTP------------------------QPFTTMQPTT--T--
--PQPTTT-----------------MQPTTTPQPTTTSH-----P-TTTPDPS--STPII
-TTKSLPTSVGTELSSPTPAPTVKPSLHPELTFTAPAPHPSTSQMPTLEP---SPALESS
SSSSSTTTSIDPLSTEDFKPSRSQSPSLTPPPTHAPHSASDLTVPP----DPHLSPIAHP
LDQPPFDHLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------HVVEQDRQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRLAEVT--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPTMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------GDCAGERATPSLPLTLPHPL--------
-PSL--------PAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 526)

CAGQRVANSRD--DSTSPLDGAPWPGLLVELSPSTEEPLVTN
APRPAGSPQN--TSRKKSPRP-KQAKSTRAPLLMTGAPRQERLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VSGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

TG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 852)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSKA-------------IILDDLRCR
---G-------N------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------EIHLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VNGSSRCSGRVEVLR-NMQWGTVCDDGWDLNDA
GVVCRQLSC-----APG-GARFGQG---SERIWLDDVNCKGTEASLSECT-AR--PWGDH
NC------N-HGEDASAM

ENSGT00900000140803_2_Linker_2_3 (439, 526)

CAGE--------------------------------------
----------------------------------------IPLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VNSSSRCAGRVEVLH
NRQWGTVCDDSWDLTDAEV-VCRQLGCGT-----ALSAPKEAWF----GQGSERIWLDDV
SCRGTEDALSECNSRTWGEHN---CNHTEDA------SAVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

S------------------
------------------------------------------------------------
----------------GEIPLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

VNGSSRCAGR-----VEVLHNLQWGTVCD--DS-WDL
TDAGVVCRQLGCGTALSAPGGARF--------GRGSER-------------IWLDDVSCR
---G-------TEASLSECKSRSWGDHNC---NHGEDANAVCSAG---------------
------------------------------------------------------------
---------------------------------------------------------REI
LLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGSSRCAGRVEVL-HNQ---EWGTVCDDSWDLQDARVVCRQLGCGMAL
S-APSGAQFGQGSQHIWLDEVTCAGTESAISECMARPWGKH---NCNHREDAGVVCSD--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------S--------VIPDTVPLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VN-GSSHCAGRVE
VLHNHKWGTVCDDSWDLQDAGVVCRQLGCGTALSAP----GAAHFGQGSDIILLDEVQCT
GTEAGLEECQARPWGEH---NCNHGEDASVVC

ENSGT00900000140803_2_Linker_9_11 (1473, 1517)

SV--------------------------
-------KRTWE-LRL

PF00530 // ENSGT00900000140803_2_Domain_11 (1517, 1734)

VDGPN---RCAGRVEVLH-DQQWGTVCDDGWD-LTEARVVCR--
-Q-LGC--------GTALAAPHGS------------------------------------
------------------------------------RF----------GHGTGRIWL---
-DEVNCTGTEVA------LSECR--------AKPWGEHN---CNHVEDAGVECS------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------VFA--------------------DP---
--------------APLRL

PF00530 // ENSGT00900000140803_2_Domain_15 (2000, 2237)

VNG----------------------------PNRCAGRVEV
LHDQQWGT---------------------VCDD----GW-----------DLH--DATV-
-VCRQ--LGCGTAL--------------------------------------------AA
PGEAWFGYASDHIWLTDVNCTGTEAA------------LSECRASPKGD-----------
N---KCGHKEDASVRC

ENSGT00900000140803_2_Linker_15_16 (2237, 2272)

SESADP----------------------GTAPIRL

PF00530 // ENSGT00900000140803_2_Domain_16 (2272, 2400)

VNGLSRCAG
RVEVF--YNQRWGTVCDDSW----------DLQDAEVVCRQLGCGS-------PLSAPCS
SCFGEGSGAI-------WLD--DVHCTGKEAALSECNIRPWGDNN---CNHTKDASVTC

ENSGT00900000140803_2_Linker_16_17 (2400, 2409)

S
DPPELRLA

PF00530 // ENSGT00900000140803_2_Domain_17 (2409, 2524)

DGP---NRCAGR-VEVLHDQQWGTVCDHDWD----LTDAGVVCQQLGCG---
-----TAVAAPGQARFGKGSGA-VWLN--KVNCTGTEAALLDCGAQPGADDSCRHGDDAG
AVC

ENSGT00900000140803_2_Linker_17_18 (2524, 2562)

SVLRSTEMGPFLQGGTFWAAVSESLAWLC-SPPPPLRL

PF00530 // ENSGT00900000140803_2_Domain_18 (2562, 2662)

VNGPSRCAGRVEVLHDQQW
GTVCDDGWDMQDAGVVCRQLGCGTALSAPGEAWFGQGSDRIWLDEVQCRGAEAALSRCRA
QPWGDHN---CHHGEDAGVVC

ENSGT00900000140803_2_Linker_18_19 (2662, 2703)

SDM-------------------------------APL-R
LA

PF00530 // ENSGT00900000140803_2_Domain_19 (2703, 2807)

NGSSRC-----AGRV--EVLHDQQWGTVCDRGWDLQDAGVVCRQLGCGAALPAPHEAR
FGRGSGPIWLDDVRCTGTETALSDCWARP---WGVRLCTPSST---

ENSGT00900000140803_2_Linker_19_20 (2807, 2833)

VILTQ---------
-----APQLRLA

PF00530 // ENSGT00900000140803_2_Domain_20 (2833, 2933)

NGPSRCAGRVEVFQYQQWGTVCDG-GWDLQDAGVVCRQLGCGTALAAP
HGAHFGPGSNPIWLDQVTCNGTEATLSECLARPWGD---NKCHHGEDAGAVCSG------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------PT--
-ADNSC-------

PF00431 // ENSGT00900000140803_2_Domain_11 (1574, 1719)

-GGFLSQPSGYFSSPFYPGNYPNNARCLWDIEVPNNYRV----TVVF
RDVQ------------------L------EGGCNYDYI----------QVFDGPSHSSPL
-IARVCDGAKGSHTSSSNFMSIRFVSDGSITRRGFQAE

ENSGT00900000140803_2_Linker_11_15 (1719, 1732)

YYS-SPSNDNTKL

PF00100 // ENSGT00900000140803_2_Domain_15 (1732, 2392)

LCLTNH---
MQ----ASVSRSY-----------------------LQSLGYSSTDLVISTWNESSRCQP
QITASQVTFTIPYSGCGTIEQADNDTI-------TYSNFLK-------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VTV-------------------------------PSAIIKRKKD
LRIHVSCK---------------------MLQN----TWLDT--MYIANDTIDVNEV---
--------QYGKFV----------------------------------------------
-----------------VNISFYTSS------------SFLYPVTSSPY--------YVD
L---NQNLYLQAEIVHADTNLS----------------------------L--FVDTC--
---VASPYSNDFTSLTYDLI--------------------RSGCARDSTYQSFSRPSPRV
ARFKFSSFYFLRRFPSVYLQCQMVVCRAD-DAFSRCRR---------GCVVRSKRDV-GS
YQEKVDVVLGPIRLQ---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 526)

CAGQRVANSRD--DSTSPLDGAPWPGLSVELSPGTEEPPVTH
GPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VSGPHRCAGRLEVWH
SGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 745)

TG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-FVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPQ
QPDPAAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASILEKTTTKAPGKMPKS
TKKWVTKYAKRPTTQPPLTPTTKHSRAQ---SPPDLTSHTTT-A-LTTEAS---RRPTAE
FTRRPTPEAPQRWTSHTTATLTPQAPRERTTKTTAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPQSPKD---PAPSPSASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1473)

-GPNRCAGRLE
VWHAGLWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGATT
ARVPGHTLPWGT-TRRTGISS---PATRRLPDT--GGKDGYKLPWTWDT-PSGRGLA---
EGTPTAGKLGLTLGAGTTRSPGSP-PTPRVHGDTGSPRKP-----WPERRPPR--PAAT-
RTA-PPTPSPGPSASPGPPGPAL---T---SDCSPELTP-HPAL--KPKATSDPPDTSPP
-----TPDPTSR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PSPTPLPTLPKE----------------LPSDPSTPSEVTSLSPTSEQ-IPE---SDTTP
DLDTTPYSSTVSE--------YSRSPAPSPSPHPTTIPDPT------MTP------DYTT
TPNPTMTPQFPTTTHPTTTPQ-------PTTITHSTMIPDPTTTPQPFTTMQP-------
----------------TTTPHPTTT-----------------------------------
------------------------------------------------------------
-------------------------------------PH-----P-TTTPDPS--STPII
-TTKSLSTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQMPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTISP----DPHLSLIAHP
LDHPPLDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
ELQRLT------QVVEQDRRERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRLAEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLSVELSPSTEEPLVTH
VPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEALLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKYTKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTAE
FTRRPTTEARRRWTSHTTATLTPQAPRERTTKTIAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSAGTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
ARVPGQTLPWGT-TRRMGISS---PATSRLPD----------------------------
---------------------------------TGSPRKP-----WPERRPPR--PAAT-
RTA-PPTPSPGPSASPGPPGPAL---T---SDCSPELTP-HPAL--TPEATSDPPDTSPP
-----TPDPTSR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PLPTPLPTLPKE----------------LTSDPSTPSEVTSLSPTSEQ-IPE---SDTTP
DLDTTPYSSTVSE--------YSRSPDPSPSPHPTTIPDPT------MTP------DHNT
TPNPTVTPHFPTTTHPTTTPQ-------PTTITHSTMIPDPTTTPQPFTTMQPTTTP---
---------------------------HP-------------------------TTPHPT
TTPHPTTTTHSTMIPDPTTTPQPFTTMQPTMIPHPTTTPYPTTTSHPTTTPHPIT--T--
--PDPTTT-----------------PHPTTTPDPTTTPH-----P-TTTPDPS--STPII
-TTKSLPTSLGTELSFPTLAPTVKPSLHPQLTFTAPAPHTSTSQMPTLEP---SPALESS
PSRSSTATSMDPLSTEEFKPPRSQSPNLTPPPTHTPHSASDLTMSP----DPHLSPIAHP
LDHPPLDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVGDD------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-SLILA--
-ICTRPGFL----------ASPSGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VGGLHRCEGRVEVEQ-KGQWGTVCDDGWDIKDV
AVVCRELGCGAASGTPS-GILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQ----EEVY-
DC------S-HDEDAGASCENP--------------------------------------
---------------------------------------ESSF-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------FPV----------------
------------------------------------------------------------
----------------------------------------------------------PE
GVRL--A-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

DGPGHCKGRVEVK-HQN---QWYIVCQTGWSLRAAKVVCRQLGCGRAI
LTQKRCNKHAYGQRPIWLSQMSCSGREATLQDCPSGPWGKN---TCNHDEDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFDLRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VG-GNNLCSGRLE
VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL--SPSFKDRKYYGPGVGRIWLDNVRCS
GEEQSLEQCQHRFWGFH---DCTHQEDVAVICSGQYPGVLD-------------------
-----------------A------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------NSPLF-SHLSL--
-QPISCLFA----------ETPPRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGPHRCEGRVEVER-NGQWGTVCDDGWDLEDV
AVVCRELGCGAAKTSPS-GTVYGPLAENNQNVLIQNVKCNGMENTLAQCEQD---EDVY-
GC------G-HEEDAGASCE----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------KIPFSLV----------------
------------------------------------------------------------
----------------------------------------------------------PE
SVRL--S-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1137)

GGPGRCAGRVEVR-HAS---RWSTVCKAGWGLPAAKVLCRQLGCGRAL
MAVGQCSSSVEGRGSIWMSKMKCSGKEATIQDCTSGPLK-D---NCTHYDDTWVECED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AIQLKLVG

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1469)

-GDGICSGRLE
VWHKKKWGTVCDDSWGAKEDQVVCKQLGCGKPL--ISPS--RKRYGPGVGRIWLDDVRCS
GKEQSLDQCKHRFWGYH---DCDHTEDVGDFDPAHIHMGYA-------------------
-----------------YLLC---YF----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLLLELSPSTEEPLVTH
APRPAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSPPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPQ
QPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKNAKRPTTQPPVMPTTKHSRAQ---SPPDLTSQTTA-A-LTTEAS---RRPTSE
FTRRPTTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKS-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSVSTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTT
AGVPGHTLPWRT-TRRPGSSS---PAIRRLPDT--GSKDGYKLPWTWDT-PSGRGLA---
EGTPTAGKLGPTLGAGTTRSPGSP-PTLRVHGDTGSPRKP-----WPERRPPR--PAAT-
RTA-PPTPSPGPSASPGPPGPAL---T---SDSSRELTP-HSAL--TSEATSDAPDTSPP
-----TPDPASR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PSPTPLPTLPKE----------------LTSDPSTPSEVTSLSPTSEQ-VPE---SDTTP
DLDTTPYSSTVSE--------YSRSPDPSPSPHPTTTPDPT------MAP------DPIT
TLNPTVTPHFPTTPHPTTTPH-------PTTITHSTMIPDPTTTPQPFTTITHS------
----------------TMIPDPTTT-PQPFTTMQPTTTPHS-------TTPHPTTTPHPT
TITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTM--T--
--PDPTTT-----------------PYPTTTPDPTTTPH-----P-T-TPDPS--STPVI
-TTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSP----DPLLSPTAHP
LDHPPLDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQERQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRLAEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MPRKGWPPLGL-------------
--------------------PLILSPLTSLAAVLVGTQATERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHGCAGRLEVWH
GGRWGTVCDDGWDLRDATV-ACRQLGCGG-----ALAAPGGARF----GPGEGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHTEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTGMRASTEGCPFCLPQTPG
TSAPHRKAWPPFFPVFLCSLPITLSSLPSFLPSFLPSFLPSFLPLFLYYFTAEKMREREL
VVPQGLSHCNRTPDACPAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IILDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGKWDLKEG---------
------------------------------------------------------------
----------------GASAPGVGGKGPG-WNYPSTSAT-------A-IELHMLAPPRSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

SGPSRCSGRLEVW-HDG---RWGTVCDDSWDTRDSAVVCRELSCGGPR
QLDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGTP
GLDTVSDPFSWSWLPGLGRDQDAWLPGELVTKPS----ASVTASVLEKT-TKAPGKVPKS
TKKWMTKTARRPTMQPPAMPVTKRPRVPGTQRPPEATSRT------------------SE
SSKRSTTKAPQRWASQTTARLTLQVPQEWTSKTVAVPSTRSHQEVTSEVTTRK-IPQASL
EPS-----A-ESP-EGSPESPID---PSLSPSADTPG-PSGPFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDSWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSETSLMDCPSGTWGKH---NCDHEEDVGLTCTGYIGDDDYPPWTWDPTAGDDLLQGTTG
TAGPGHTVSWGT-TRHPEVPA---PVTQRLPDT--DDQDGYKSSRTWDT-SLGPDLT---
QQTLTTAKPGPTVTTATIRSLGHPSLVPRTHGNTGSPGKP-----RPEPRPLRTAPT---
------TSSLTPSSSPGPSGSQL------TADSWPHLDS-DWASKQEEEVTTDPPDTSPP
-----TPGLAS------------------LTSADLA-------LSTSESSAFP--TRAPE
SSSGPPSTLSKE----------------PTSDPTALSHGTSLSPTSER-TPG---SDTAS
DLNTMPHTTTVPE--------SSGFPDLYTTPQLTAASPSATTPQ---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------LPTTTFPT--STPLV
-TTQSLPTSPVTELP-LTSTVRAKPSLHPQLTP-----HDLTSQKQNVES---SPASESR
PSRPTPALSTDSLSTE--EPPRSQSPKSTLPSTQTPPSTFDPTVAP----DLHLSTTAHP
LGS----------IPSHIPGPLGPCISPTP-----PVKVMACEP-PALVDLVAAVKDVGN
QLRRLT------QVLEQDLQERQALGLGLVQLVEAVQGLGQLGETV--------------
---------------------------------KRLAEVA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WPPSTPLPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MALLF-FLILA--
-ICTGPGLL----------ESSSSVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VSGPHHCEGRVEVKR-DGQWGTVCDDEWDLNDV
AVVCRELGCGAATGTPS-GEIYKPLAEEMQPILISEVKCNGTENTLAQCGQE---DDVY-
DC------P-HKEDAGASCESP--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------V----------------
------------------------------------------------------------
----------------------------------------------------------PE
TVRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-GGPGRCVGRVEVK-HQD---QWGTVYQAGWNLSAAKVVCQQLGCGKAT
LTRTYCDKASHGQGPIWLSQVSCTGQELTVLGCHSEPWGKN---NCTHEEDTWVHCED--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELKL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

EG-GDNHCSGRLA
VRHKGTWGSVCDDGWGEKENQVVCRQLGCGKPL--SLSPKARKPFGRGVGHIWLDDVHCS
GRERSLEKCQHRFWGRH---DCTHKEDVAVICSAQ-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-ICTGPGLL----------GSSLRVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

VSGPHRCEGRVEVEQ-NGQWGTLCDDGWNLKNA
AVLCRELGCGAAKGTPS-GLKYLPLADKNQDIINQQITCSGMEASLAQCKLE---ELDYG
IC------T-HEEDSGAACDP---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------F----------------
------------------------------------------------------------
----------------------------------------------------------PE
PVQL--A----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPNRCEGRVEVK-HQG---QWGSVCKAGWNLHAAKVVCRQLGCGRAL
LTQAYYNRAVQGQWPIWLSWVSCSGEELTLQECSLSPWGES---TCTHDQDTWVQCEG--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PFELR

PF00530 // ENSGT00900000140803_2_Domain_9 (1367, 1473)

LEG-G-NHCAGRLE
VLHRGLWGSVCDDDWGEKEDQVVCKQLGCGKPV--SRPSHAKKPFVPGAGQIWLDNVRCT
GNETSLEQCQHRFWGYH---DCTHKEDVAVICS---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLLMELSPSTEEPPVTH
GPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MTSQAPGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSAVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKYAKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTAE
FTRRPTTEAPRRWTSHTTATLTPQAPRERTTKTTAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
ARVPGHTLPWGT-TRRTGISS---PATRRLPDT--GGKDGYKLPWMWDT-PSGRGLA---
EGTPTAGKLGPTLGAGTTRSPGSP-PTPRVHGDTGSPRKP-----WPERRPPR--PAAT-
RTA-PATPSPGPSASPGTPGPAL---T---SDCSPELTP-HSAL--TPEATSDPPDTSPP
-----TPDPTSR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PSPTPLPTLPKE----------------LTSDPSTASEVTSLSPTSEQ-IPE---SDTTP
DLDTTPYSSTVSE--------YSRSPAPSPSPHPTTIPDPT------MTP------DHTT
TPNPTVTPQFPTTTHLTTTPQ-------PTSITHSTMIPDPTTTPQPF------------
------------------------------TTMQPTTTPHP-------TTPHPTTTPHPT
TTTHSTMIPDPTTTPQPFTTMQPTMIPHPT-TPYPTTTPHPTTTPHPTTTPHPIT--T--
--PDPTTT-----------------PHPTTTPDRTTTPH-----P-TTTPDSS--STPII
-TTKSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQMPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTMSP----DPHLSLIAHP
LDHPALDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRVVEMA--------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------LRLVNSTNY

PF00530 // ENSGT00900000140803_2_Domain_9 (1374, 1473)

GCSGRVE
VFANGKWGSVCDSFWNILTAGVICRQLGCGNAIAAP----RKAFYGPGTGPVILNNVWCK
GNEANLWQCHNSGWFSQ---SCDHHDDASVTC

ENSGT00900000140803_2_Linker_9_11 (1473, 1574)

SEQSVKD---------------------
------------------------HFDGTLNSFV----------------------ST--
-ANYTC-------

PF00431 // ENSGT00900000140803_2_Domain_11 (1574, 1719)

-GGYFSQPSGKIFSPNYPKQYSNNTNCFWDILVSSNFVV----TIVF
GDVD------------------L------DENCDMDFI----------EIYDGPYQSSPR
-ITRICGNKRGTFRSTTNFLSVRFSSNSGNSKRGFQAH

ENSGT00900000140803_2_Linker_11_15 (1719, 1732)

YFS-IPSHNGTSL

PF00100 // ENSGT00900000140803_2_Domain_15 (1732, 2389)

TCSQEQ---
MT----AIFSKEY-----------------------LKSLGYTTWNFVLY----NSSCVI
MENRTNIIVEIPYDSCGTKKTITSDTI-------NYSNILR-------------------
------------------------------------------------------------
------------------------------------------------------------
----------------INQTIR----------------------------HSDIITRSES
LHLHVSCR---------------------MLKN----TWVEA--MFATTGGIDITEV---
--------RYSNYH----------------------------------------------
-----------------VELSFYETS------------AFIIPVNSTPY--------YVK
L---NQDLYLQAEILHTDASLT----------------------------L--FVDTC--
---IASPSPDDFTTLTYDLI--------------------RNGCAKDETYITYDSPFPQK
ARFGFKSFSFLEKHPFVYLQCKMVVCRAF-DYTSRCYK---------YCMERTKRDT-ST
YEEKLDIVLGPIELEKEDEKEDRNLDLAV--VDVQGPYEYNK--------LYQPIAASIG
VFIAVVVVF--GAFQLKKRS----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-IDTGLGFL----------DVPHSLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (328, 1021)

VGSRRSCEGRVELWK-DGQWGTVCDDHWTNEVA
AMVCRELQCGPLMSTPA-GHIYLPKAQRGQHVW--NLKCNGTEETLAECEE-----DFIE
PG------S---EDVGVNC-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

ENSGT00900000140803_2_Linker_3_6 (1021, 1032)

KVQL--A----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-DGPSHCIGRVEMK-YTG---EWLTVCNEGWTLQDAKVLCRELGCGRPI
LTKGSCNKDQQGTGNIWSGQMQCQGSEASLNDCPFVPME-N---NCSHKDDIWVHCEE--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------RFALRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VD-GKRNCSGRLE
VLHKGIWGSVCNDGWGEKEDHVVCQELKCGKAV--FQKSRARKSFGHGKGHIWLDDVRCK
GKETSLEQCKHRFWGYH---DCTHREDVSVICS---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MRVL--------
-ACL--------LAALVGIQAVERLRLA

PF00530 // ENSGT00900000140803_2_Domain_2 (329, 439)

DGPHGCAGRLEVWH-GGRWGTVCDDGWDLRDA
AVACRQLGCGGALAAPG-GAFFGEG---AGPVWLSELACRGNEGQLGLCHHR---GWKAH
IC------S-HEEDAGVV

ENSGT00900000140803_2_Linker_2_3 (439, 527)

CAGQRVANSRD--DSTSPLDGAPWPGLSVELSPSTEEPPVTH
GPRLAGNPQN--ASRKKSPRP-KQAKSTRAPLLTTGAPRQERLRLV

PF00530 // ENSGT00900000140803_2_Domain_3 (527, 641)

SGPHRCAGRLEVWH
GGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGAGPVWMDDV
GCGGGEQALRDCPRSPWGRSN---CDHSEDA------GLV

ENSGT00900000140803_2_Linker_3_4 (641, 745)

CTG-----------------
------------------------------------------------------------
----------------PAPRLRLA

PF00530 // ENSGT00900000140803_2_Domain_4 (745, 882)

DGPHGCAGR-----LEVWHGGRWGSVCD--DA-WDL
RDAAVACRELGCGGALAAPGGAFF--------GEGSGP-------------IVLDDLRCR
---G-------NETALRFCPARPWGQHDC---HHREDAGAVCDGMPLG-YVPPTAP--TD
-SNNSTPREAASR-PPST------------------------------------------
---------------MMSQAPGTAG-----VSTPPASPT-------VLWEPGPE--AGSP
QLRL--V-----

PF00530 // ENSGT00900000140803_2_Domain_6 (1033, 1136)

AGPSKCSGRLEVW-HDQ---RWGTVCDDSWDMRDSVVVCRELGCGGPR
QPDPAAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGPP
GLDSISDPFSWSWIPGLGRDRDAWLPGELATKPS----ASVTASVLEKTTTKAPGKMPKS
TKKWVTKYAKRPTTQPPLTPTTKHSRAQ---SPPDLTSQTTT-A-LTTEAS---RRPTAE
FTRRPTTEAPRRWTSHTTATLTPQAPRERTTKTTAMLTTQGPQEMTSEATIKR-IPQASL
EPS-----A-EIP-EGSPESPKD---PAPSPSASTTG-ESGLFRVRLAD

PF00530 // ENSGT00900000140803_2_Domain_9 (1370, 1472)

-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV----GKTHYGPGTGPIWLDDMGCK
GSEASLSDCPSGAWGKH---NCDHEEDVGLTCTGYTDYDDYPPWTWDPTSTEDLAKGTTT
ARVPGHTLPWGT-TRRTGISS---PATRRLPDT--GGKDGYKLPWMWDT-PSGRGLA---
EGTPTAGKLGPTLGAGTTRSPGSP-PTPRVHGDTGSPRKP-----WPERRPPR--PAAT-
RTA-PATPSPGPSASPGPPGPAL---T---SDCSPELTP-HSAL--TPEATSDPPDTSPP
-----TPDPTSR--TNPDL---------ILTSPDFA-------LSTPDSSVVP--ALTPE
PSPTPLPTLPKE----------------LTSDPSTASEVTSLSPTSEQ-IPE---SDTTP
DLDTTPYSSTVSE--------YSRSPAPSPSPHPSTIPDPT------MTP------DHTT
TPNPTVTPQFPTTTHPTTTPQ-------PTTITHSTMIPDPTTT----------------
--------------------------PQPFTTMQPTMIPHP-------TTPYPT------
------------------------------TTPHPTTTPHPTTTP------HPIT--T--
--PDPTTT-----------------PHPTTTPDPTTTPH-----P-TTTPDSS--STSII
-TTKSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQMPTLEP---SPALESS
PSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTMSP----DPHLSLIAHP
LDHPPLDPLTLGPTPGQSPGPHGPCVAPTP-----PVRVMACEP-PALVELVAAVRDVGG
QLQRLT------QVVEQDRQERQALLLGLTQLVEAARGLGQLGEAV--------------
---------------------------------KRVVEMA--------------------
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--------------------WTTSMPAPTTTTPEE--EERPLRGDV--------------
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-------------------------------------------------MRV--------
-ACL--------LAALMGIQAVERLRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 440)

ADGPHECAGRLEVWH-AGRWGTVCDDGWDLRDA
AVACRELGCGGALAAPG-GAFFGEG---AGPVWLSELACRGGEGQLGLCPHR---GWKAH
IC------S-HEEDAGVVC

ENSGT00900000140803_2_Linker_2_3 (440, 526)

AGQRVAANSK--ESAPLVDGDPWLGLSREFSLGSEVPPTTS
APRLVGNSQNSGGSRKKSPRPPKQAKSTRAPVLITGGPRQERLRL

PF00530 // ENSGT00900000140803_2_Domain_3 (526, 642)

VSGAHGCVGRLEVWH
AGRWGTVCDDGWDLRDAAV-ACRELGCGG-----ALAAPGGARF----GPGS-PVWMDDV
GCGGGEQTLRDCPRSLWGR-S---CDHSEDA------GLVC

ENSGT00900000140803_2_Linker_3_4 (642, 744)

TG-----------------
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----------------PAPRLRL

PF00530 // ENSGT00900000140803_2_Domain_4 (744, 883)

ADGPHGCAGR-----LEVWHAGRWGTVCD--DA-WDL
RDAAVVCRELGCGGALAAPGGAFF--------GEGAGP-------------ILLDDLRCR
---G-------NETALRFCPSRAWSQHDC---HHREDAGAVCDGMPLG-YVPPTMP--TM
GNNNSTSR------TLPP------------------------------------------
---------------MVTQTLWTAG-----ISLPPASPT-------VPPERRSA--AGSP
HLRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-AGPNKCSGRLEVW-HAG---RWGTVCDDGWDLRNSAVVCRQLGCGGAR
QPDPPAGRFGWGAGPIWLDDVACVGTEASLSDCPAAPWGKH---NCAHNEDVGVTCTGTP
GQDSISDPLSWSWIPELGRDRDAWLPGELATKPA----SRLIPGAPEKTTTKAPGKMPKS
TKKWVTKHARRPTTQPPMMPTTKYSRGSGTQNSLELTSRTTSP---------------SE
FTTRLTTEAPHRLTSHTTAALTSQASQELTSKTLATLTTQGYREVTSKAPIKQ-IPQTSM
EPS-----S-EIFE-----SSKD---PSPSPTGIATG-ESGPFRVRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

AD-GPNRCAGRLE
VWHAGRWGTVCDDNWDLRDASVACWELGCGRVRPRV----GKTHYGPGTGPIWLDDMGCR
GNEASLSDCPAGAWGKH---NCDHEEDVGITCTGYTDDEDYPPWTWDPTLGEDLTKGAST
AGAPGLTSSWGT-TRNPGTPS---PAARRHPDT---------------------------
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-----------------------------------------------MVLLF-FWMLA--
-IRTAFGFS----------DPLYGVRL

PF00530 // ENSGT00900000140803_2_Domain_2 (328, 439)

VGGENRCEGRVELWK-DGQWGTVCDDHWKKEIA
TMVCQELRCGPVMKTPA-GRLYYQSC-LVQHIW--NPMCQGTELTLAECEE-----DVVD
CD------N-HEEDAGAICGVP--------------------------------------
---------------------------------------L--------------------
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-------------------------------------------H----------------
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----------------------------------------------------------LE
GTRL--V----

PF00530 // ENSGT00900000140803_2_Domain_6 (1032, 1137)

-NGPGPCTGRVEVK-YAG---EWGTVCNEDWNLQDAKVLCHELGCGRPL
LTKGSCKKDQQGRGEIWLSQVKCRGSEASLRDCPTAPVGEN---NCTHYDDVWVQCEE--
------------------------------------------------------------
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-----------------------------------------PFALRL

PF00530 // ENSGT00900000140803_2_Domain_9 (1368, 1473)

VD-GGDKCSGRVE
VFHKGLWGSVCNDGWGEKEDQVVCQEMKCGKAL--LQKSGTRKRFGLGKGQIWLDDVSCK
GKEASLKQCQHRLWGRH---DCTHREDVSVVCSG--------------------------
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