Query Results 

-------------------------------------------------------MGSRP
T---R--ASGSLMILPLLWLFVLLKNTTPFHVTVQDDNSIVVSLEASDVVSS-SSVYVVK
ITGESKNYFFQFEEFNSTLPAPVVFNASYHGLYYIITLVVVNANVMIKPARSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGISHEPKQHRTAPFPPQNISVRIVNLNK-N
NGEEESGSYPEESFLKPQDV----TEKEKLLHFTDDPPEISS---------ANTSSGWPD
F--N-SSDEETTLQPYWWDSETVTPESEDEFVSVLPREDKMNNTVSP--IE-SASAPLSF
FPVQMILNWLPPKPPTAFDXXXXXXXXXX-NSTEFLXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXPMGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVRVNVLSSTTALMSWTSSQ--
DSDSNNTIVSVVSLTCQKQKESQRLEKHYCTQVNSSKSIIENLVPGAQYQVVIYLKKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGAFRKYVVEMFYFNPATMIS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGEPELSCCDSSTISFITXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX-----XXXXXXXXXXXXXXXXX-XXXX
XXX-XXXXXXXXXX--XXXX-----XXXXEPVSVSSHVVTISSLLPATAYNCSVTSFSHN
SPSVPTFIAXXXX--XTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKEMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPXXXXXXXXXXXXXXXXXXXXXXXXXXGYNSPQEYIATQGPLPETRNDFWKMVLQ
QRSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMTSEEEHSDW--AYRS
FRIS--YADEMQDIMHFNYTAWPDHGVPTTNAAESIMQFVQMVRQHCTKSRGPMIIHCSA
GVGRTGTFIALDRLLQHVCDHEYVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKRQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
T-GIH--GA--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEILS---------GNISSGWPD
F--N-SSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLMLDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGGVM
CNGCH--GGVHLNLTCLLFFSFLKQNATAFHVTVQDDNSIVVSLEASDVISP-TSVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGSFPEEAFMRSQDTIQDTIGKDKLIHFTEETSEIPS---------GNISSGWPD
F--N-SSEYETTSQPYWWDSASATPESEDEFVSVLPMEYENNNTLSE--TEKSTSGSFSF
FPVQMILSWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWNRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIAHLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDNTTNLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SNRE-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSINEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATRSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
-------------------------NAATFQVIVRDDNSIAVSLEASDVISP-ASLYVVK
ITGESKNYFFEFEEFNNTLPPPVIFKANYHGLYYIITLVVVNGNVVTKPSRSVTVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKAFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEQ--SSFPEESFLPS-P---TTEK-DKLLHFXXXXXXXXXX---------XXXXXXXX
X--X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-NFTEYLTVGEEAHEFVAELKEPGKYKLSVT
TFSASGSCEARKSQSAKSLSFYISPTGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTTALMTWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKRIIENLVPGAQYQVVMYLRKGPL
IGPP

ENSGT00900000140785_8_Linker_0_1 (605, 615)

SDPVTFAI-V

PF00041 // ENSGT00900000140785_8_Domain_1 (615, 702)

PTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDP

ENSGT00900000140785_8_Linker_1_2 (702, 810)

ELSCCDSSTISFITAPVAP
EITSVEYFNSLLYVSWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLIKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVGSG--QE-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHN
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVSTM--VTDMKPSVEVISVLAILDTFPIGRLIVALLI-----LRKYQ-NGR
--AECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1304)

XXXXXX
XXXXXXXDFSRVRLVSMNEEEGADYINANYIPGYNSPHEYIATQGPLPETRNDFWKMVLQ
QKSQMIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVTHFNYTAWPDHGVPTANAAESVLQFVHMVRQQATKSRGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTE----------------
-------------------

-------------------------------------------------------MGHLP
TRTRG--G----RLLPLLWLFVLLKSATAFHVTVQDDNNIVVSLEASDVTNP-ASVYVVK
ITGESKNYFFEFEDFNNTLPPPVTFKANYHGLYYIITLVVINGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVHFVNLNK-H
NWEEQSGSFPEDSFIKSQD----STGKDKLFHFTDEAPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPENEDEFVSVLPVEYGNHSTLSK--TEKSTSGSFTF
FPVQMILSWLPPKPPTAFDGFHILIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGGCETRKSQSAKSLSFYISPAGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKKYCTQVNSSKPIIENLVPGAQYQVVVYLRKGPL
IGPPSDPVTFAI-VPTGIKDLILYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPVTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSTLHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SGQG-----PTLQEPIAVSSHVVTVSSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
IPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPI-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKKQFCISDVIYENVSKS-

--------------------------------------------------MGHLATR-A-
-----RGSSRLLPLLWLF---VLLKNATTFHVTVQDDNSIIVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPPPIIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIISLNK-N
NWEEQSGSFPDESFMRS-Q---DTMG-NKLFHFTDETPEIPSV---------SISSGWPD
F--N-SSDYEATSQPYWWNSASATPESEDEFVSVVPMEY-ENNNT-LSETEKSTPGSFSF
SPVQMILSWLPPKPPTAFDGFHIHLEREE-NFTEHLTVDEEAHEFVAELKEPGKYKLSVT
TFSSAGSCETRKSQSAKSLSFYISPSGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTSALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIVENLVPGAQYQVVIYLRKGPL
IGPP

ENSGT00900000140785_8_Linker_0_1 (605, 615)

SDPVTFAI-V

PF00041 // ENSGT00900000140785_8_Domain_1 (615, 702)

PTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDP

ENSGT00900000140785_8_Linker_1_2 (702, 810)

EMSCCDSSTISFVTAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGK-KIKKSV-TRNVMTAVLSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
IAD-FFEVFCQQVGSN--QE-----TKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--XXXXXXXXXXXXXXXXXXXXXXXXRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGIK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLFSMNEEEGADYINANYIPGYNLSQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEDEQDDW--ACRH
FRIS--YADEMQDVMHFNYTAWPDHGVPTTNAAESILQFVHTVRQHATKSRGPMIIHCSA
GVGRTGTFIALDRLLQHIQDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLS
T-GIH--GG--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLETSDIISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
SPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TELQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
---------------------------TTFHVTVQDDNNIIVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEEFNRTLPPPVIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTILYKDLFRGKTVFN
HWLPGICYSNITFQLVSEATFNKTTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEQSGSFPEESFLRSRDP----MGKDKLFHFTDETPEIPF---------GNISSGWPD
F--N-SSDYEATSQPYWWDSASARPESEDEFVSVLPMEYENNNTLSE--TEKSTSGSFAF
FPVQMILSWLPPKPPTAFDGFHIYIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVA
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGRKKIKKSV-TRNVMTAILSLP
AGDIYNLSVTACTERGSNTSMLHLVKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFQVFCQQVG--SNQE-----TKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

STPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLTKQSPV-QLDDFDSYIKDMAKDSDYKFSLQFEDLKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIS--HADEMQAVMHFNYTAWPDHGVPTANAAE-ILQFVHMVRQQATRSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
T-GIH--GA--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHKPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEILS---------GNISSGWPD
F--N-SSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLMLDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
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------------L--VTEMNPNVVVISVLAILSTLLIGLLLVTLVT-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLLSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPVAYGDITVEVISEEEQEDW--ASRH
FRIN--YADEVQDVMHFNYTSWPDHGVPPANAAESILQFVYTVRQQATKSRGPMVIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVGKS-

-------------------------------------------------------MGHL-
PART----RGGRRLLPLLWLFVLFKDATTFHVTVRDDNSIAVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPPPIIFKANYHGLYYVITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEESGSFPEESFMRSQDT----VGKDKVFHFTDDTPEIPS---------GNISSGWPD
F--N-SSDFETTPQPYWWDSASATPESEDEFVTVLPTEYENNSTLSE--TEKSASSSFSS
FPVQMILSWLPPKPPTAFDGFHILMEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRNSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWIYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAVLSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQIG--SSQE-----AKLQEPISVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAISTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRRKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMMSEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHKVRQQAMKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSNS-

-------------------------------------------------MGKLNNFRGT-
TI-----LF-PLLLLWSFLAGCVFNNAEPFQVAVREDNCIIVSLEASDVVSS-SSVYVVK
IAGESKNYFFQFDEFNSTLPAPVVFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPL
PVSNVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVQHEPKQHRTVPYPPRNISVQIVPANR-N
NWEEHSGNFAEESFMGP-Q---EIIRK--VSHPAESLAEMPA---------ANTSAAWLD
EPPN-STEYETTSQPSWWSNEAESSEGEEEFVSAVSSDYGG--SD-A---SRATAEPPPF
LPVQMVLTWLPPKPPTAFDGFHINIEREE-NSTESLTVSEDTHKFVAELKEPGKYKLSVT
TFSSSGSCEVRGSQSAKTLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVTVRVLSSTTALTSWTASH--
DSSGNSTIVSVLSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPL
VGPP

ENSGT00900000140785_8_Linker_0_1 (605, 619)

SDPVTFSI-VPTGI

PF00041 // ENSGT00900000140785_8_Domain_1 (619, 697)

KDLTLYPLGPTAVVLSWNRPFHGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAASVSLTASVRIANLLPAWYYNFRVTMV

ENSGT00900000140785_8_Linker_1_2 (697, 812)

TWGDPELSCCDSSTVSFITAPVAP
KITSVEYYNHLLYVTWTYGGDGPDLSHSRMLHWMVVAEGKKKIKKSV-TRTVMTAVLSLP
PGDIYNLSVTACTERGSNTSMPQLVKLAEPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVYCQQAGSG--QE-----TKVQEPVTVSSHVVTISSLTPATSYNCSVTTFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

N
SPSIPTFIAVSTM--VTEMNPNVVVISVLAILSILLIGLLLVTLVV-----LRRKHLQMA
RNRECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYVNPWSKNGLK
KRKLT--NPV-QLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPM

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---DPVAYGDITVEMLSEEEHTDW--VYRS
FRIS--YADEVQDVMHFNFTAWPDHGVPTTNAAESILQFVQMVRQKSAKAKGPMVIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
--------------ISFFFFFLSQQNATPFHVTVQDDNSIVVSLEPSDVVSS-SSVYVVK
ITGESKNYFFQFEEFNSTLPAPVVFNASYHGLYYIITLVVVNANVVLKPARSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGISHEPKQHRTAPFPPQNISVRIVNLNK-N
NWEEESGSFPEESFLKPQDV----IEKEKLLHFPDDPPEISS---------VNTSSGWPD
F--N-SSDEETTLQPYWWDSESVTPESEDEFVNVLPREDKNNNTISP--IEKSTSAPLSF
FPVQMILNWLPPKPPTAFDGFHIRIEREE-NSTEFLTVDEEAHEFVTELNEPGKYKLSVT
TFSSSGSCETRGSQSAKSISFYISPLGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVRVNVLSSTTALMSWTSSQ--
ENDNNNTIVSVVSLTCQKQKESQRLEKHYCTQVNSSKSIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAIVVPTGIKDLMLYPLGPTAVVLSWTRPYLGAFRKYVVEMFYFNPATMIS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGEPELSCCDSSTISFITAPVAP
EITSVEYFNNLLYISWMYGDDTTNLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAVLNLP
PGDIYNLSVTACTERGSNTSLPHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEDG
VVD-FYKVFCQQVG--SNQE-----IKLQEPVSVSSHIVTISSLLPATAYNCSVTSFSHN

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAISTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDTYIKEMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNLPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMTSEEEHSDW--AYRS
FRIS--YADEMLDVMHFNYTAWPDHGVPTTNAAESIMQFVQMVRQHSTKSRGPMIIHCSA
GVGRTGTFIALDRLLQHVCDHEYVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKRQFCISDVIYENVSKS-

--------------------------------------------------MGHLPR-ER-
-----RGGRRLLPLLGLF---VLLKIVSTFHVTVRDDNNIVVSLEASDVVSP-TSVYVVR
VAGESKNYFFEFEESNGTLPPPVVFKATYHGLYYIISLVVVSGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGKDFRTMLYKDFLKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVECSGVSHEPKQHRTAPYPPRNISVRFVNLNK-N
NWEEPSGSFPEDSFIKP-Q---DAIGRDRPFHFPEETPETPAS---------NASSGWPD
--PN-GTEYESTSQPYWWDSASAAPENEEDFVSVLP-ADYDTEAT-LGRTEKPTADPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREG-NFTDYLTVDEEAHEFVAELKEPGKYRLSVT
TFSSSGACETRKSQSAKSLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALLSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTSSVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRRKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVLCQKLGSG--HD-----GKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEVNPNVVVISVLAILSILLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFTFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSRIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMVSEEEQEDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVYTVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLK
KKQQFCISDVIYENVSKS-

MLPQFAIAGHGWEPSGGRRGAEPGVPGAQEQQPPLPGRPRRQRPPPSSPMPDR-RRRGA-
-P-----GA-RSCLLWLFV---LLKSAEPFQVAVREDNCIIVSLEASDVVSS-SSVYVVK
IAGESKNYFFQFDEFNSTLPAPVVFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPL
PVSNVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVQHEPKQHRTVPYPPRNISVQIIPINR-N
NWEEHSGNFAEESFMGP-Q---EIVRKEKGSHPSGSPTEIPA---------ANTSAAWLD
EPSNTSTEYETSSQPSWWSSEAESSEGEEEFVNAVSRDYEA--SD-ANTAGRPTAEPPPF
LPVQMVLTWLPPKPPTAFDGFHINIEREE-NSTEFLTVSEDTHKFVAELKEPGKYKLSVT
TFSSSGSCEVRGSQSAKTLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQRVTVTVLSSTTALTSWTASH--
ESSGNSTIVSVLSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPL
VGPPSDPVTFSI-VPTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
KITSVEYYNHLLYVTWTYGGDGPDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAVLSLP
PGDIYNLSVTACTERGSNTSMPQLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVYCQQAGSG--QE-----TKAQEPVTVSSHVVTISSLTPATSYNCSVTTFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

N
SPSIPTFISVSTM--VTEMNPNVVVISVLAILSILLIGLLLVTLVV-----LRRKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYVNPWSKNGLK
KRKLT--NPV-QLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPM

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---DPVAYGDITVEMLSEEEHTDW--VYRS
FRIS--YADEVQDVMHFNFTAWPDHGVPTTNAAESILQFVQMVRQKSAKTKGPMVIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
----------GRRLLSLLWVFVLLKNATTFHVTVQDDNSIVVSLEASDVMSP-SCVYVVK
ITGESKNYFFEFAEFNSTLPPPVTFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEQSGSFPEESFMRSQDT----VRKDKLFHFTDETPEIPS---------GNISSGWPD
F--N-SSDYETTSQPYWWGSVSAAPESEDDFVSVLPVEYENNSTLSE--TEKSTAGSLSF
FPVQMILNWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTTALMSWTSAQ--
-ENYSGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPP

ENSGT00900000140785_8_Linker_0_1 (605, 615)

SDPVTFAI-V

PF00041 // ENSGT00900000140785_8_Domain_1 (615, 702)

PTGIKDLTLYPLGPTAVVLSWSRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDP

ENSGT00900000140785_8_Linker_1_2 (702, 810)

ELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQE-----TKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGTDYINANYIPGYNSSQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEERDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHVVRQQATKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWRK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
---------------------LLPLIVTTLHVTVQDDNNITVSLEASDIVSP-ASVYVVR
VAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIISLVVVNGNVVTKPSRSVTVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKHHRTAPYPPRNISVRFVNLNK-N
NWEEPSGSFPEDSFIKP-Q---DSIRRDRLFHFPEETPGTPP---------SNVSSGWPD
--PN-STDYESTSQPYWWDSSSATPENEEDFVSVLPVVDYDSDTT-LSRTEKPTSDPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREE-NFTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQQVSVHVLSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKELMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
DITSVEYFNSLLYISWTYGDEHTDLSHSRMLHWMVVAEGRKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVLCQQLGSS--HD-----AKLQEPIAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSPIIVMLTQCNEKRRVKCD--HYWPFTE---EPITYGDITVEMISEDEQDDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVYMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHL-
PART----RGGRRLLPLLWLFVLLKNATTFHVTVRDDNSIAVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEEFNGTLPPPVIFQASYHGLYYVITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTVPYPPQNISVRIVNLNK-N
NWEEQSGSFPEESFMRSQDT----MGKDKLFHFTDDTPEIPS---------GNISSGWPD
F--N-ISDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNNTLSE--TEKSTTSSFSF
FPVQMILSWLPPKPPTAFDGFHIHMEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCEIRNSESAKSLSFYISPSGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTTALMSWTSSQ--
-ENYISTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPP

ENSGT00900000140785_8_Linker_0_1 (605, 615)

SDPVTFAI-V

PF00041 // ENSGT00900000140785_8_Domain_1 (615, 702)

PTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIAHLLPAWYYNFRVTMVTWGDP

ENSGT00900000140785_8_Linker_1_2 (702, 810)

ELSCCDSSTISFIT-----
------------------------------LHWMVVAEGKKKIKKSV-TRNVMTTILSLP
PGDIYNISVTACTERGSNTSMLHLVKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQD-----IKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLITLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSPQEYVATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEGQDAW--ACRH
FRIN--YXXXXXXXXXXXYTAWPDHGVPTANAAESILQFVHMVRRQATKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
-------------------------TAATFHVTVQDDNSIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFQASYHGLYYIITLVVVNGNVVTKPSRSVTVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTLLYTDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXX
X-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX-XX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRNSQSAKSLSFYISPSGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTSALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYY-LAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVGSR--QE-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHD
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SIPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1258)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATRSKGPMIIHC--
------------------------------------------------------------
-------------------

--------------------------------------------------MGHLPR-GT-
-----LGGRRLLPLLGLF---VLLKIVTTFHVAVQDDNNIVVSLEASDIVSP-ASVYVVR
VAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNK-N
NWEEPSGSFPEDSFIKPPH---DSIGRDRRFRFPEETPETPPSNVSSGSPPSNVSSGWPD
--PN-STDYQSTSQPFWWDSASSAPENEEDFVSVLP-ADYDTETT-LDRTEKPTADPFSA
FPIQMTLSWLPPKPPTAFDGFNILIEREE-NFTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSAKSLSFYISPTGEWMEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPTLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSLLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVLCQQLGSG--HD-----GKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

TPSVPTFIAVSTM--VTEVNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--SPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMVSEEEEEDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
--MHLPKETRGSRRLPLLGLFVLLKNATTFHVTVQDDNNIVVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEQFNSTLPPPVIFKASYHGLYYIITLVVVNGHVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKHNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKHHRTAPYPPRNISVRIVNLNK-N
NWEEQSGSFPEESFVRSQDT----VGKEKLFHFTDETLEIPS---------GNISSGWHD
F--N-SSDYETTTQPYWWDSASAAPESEDEFVSELPMGYENNSTLSE--TEKSTLDSLSF
FPVQMILSWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVTELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISSSGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSVIENLVPGAQYQVVMYLKKGPL
IGPP

ENSGT00900000140785_8_Linker_0_1 (605, 615)

SDPVTFAI-V

PF00041 // ENSGT00900000140785_8_Domain_1 (615, 702)

PTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDP

ENSGT00900000140785_8_Linker_1_2 (702, 810)

ELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-X

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQE-----TKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVSTM--VTEMNSXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXX
--XECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLISTNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMILEEEQEDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHVVRQQATKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSQRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
T-GIH--GA--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEEIPEIPS---------GNISSGWPD
F--N-SSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLMVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKSPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------PSGEWMEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTALVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATTSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSLAEIVVTINF----
TYECYDLSVFFRM---SNIFKKTIDRI-KPKIKRSNKRLDIFSFDKRKREITLIK-V---
------EITCQGYFNSLKKNPILHDKVLSSILGTTGHLLFFPSSLHLNSKNVAITSFQHF
MIFLDLLIH---------KNSL-VCIATVASTS--NQSQLLVFINLSETPDKQDKKRNRN
--EKCWTLTLATSSSLH-LLSINAHRRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLTKQSPV-QLDDFDAYIRDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1215)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSSQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPITYGDITVEMISEEEQDDW--ACRH
FRIIYVSHE-AQGQM---------------------------------------------
------------------------------------------------------------
-------------------

-------------------------------------------------------MGHLP
T-GIH--GG--LRLLPLLWFFVLFKNATAFHVTVRDDNNIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
SWEEQSGNFPEESFMRSQDT----TEKEKLFHFTEEIPEIPS---------GNNSSGWPD
F--N-SRDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVA
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPL
VGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRVANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWNMVQQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEERDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLMQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQHFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
T-GTH--AG--LRLLPLLWLFVLFKNATAFHVTVQDDNNIIVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIINLNK-N
NWEEQSGNFPEESFMRSQDA----TGKEKLFHFTEETPEIPS---------GNNSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTANSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLISMHEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQMIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEERDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPE
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
SPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNW----------------------------SKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
-MSRL--G--RLWLFVVLLLLPLFQNVTPFQVAVRDDNCIVISLEAADVVSSLSSVYVVK
ITGESKNYFFQFDEFNSTLPAPVVFNATYHGLYYIVTLMVVSANMVSKPTRSITVLTKPL
PVTNVFIYDYKPSPETGVLFEIQYPEKYNVFSRVNISYWEGKDYRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGIKHEPTQHRTVPYPPRNISVRIVHTNLNE
NWEEHSGDFPEESFLENQNT----MGQENIPHVEDDLPVLPT---------MNTSYTWPE
YRYN-SSDYETTSQPDWWINELDSPENEDEFVNAVPTDYENINPTAE--FGTPLPKPSSF
LPVQMVLSWLPPKPPTAFDGFHIHIEREE-NFTEFLTVGEDIHEFVADLKEPGKYMVSVT
TFSSSGSCEVRESRLAKRLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQNVMATVLSSTTALLSWTTSSWE
PSNSNNTIVSVVSLTCQKQKESQRLEKHYCTEVNTSSSFIENLVPGAQYKVVIYLRKGPL
VGPPSDPVTFAI-VPTGIKDLTLYPLGPTAMVLSWNRPYLGVFRKYIVEMFYFNPSTMTS
EWTTYYEIAATVSLTSSVRIGNLLPAWYYNFRVTMVTWGEPELSCCDSSTISFITAPVAP
EITSVEYFNNLLYVSWIYGDDNTDLSHSRMLHWMVVAEGKRKIKKSV-TRNAMTAVLNLP
PGDIYNLSVTACTETGSNTSASQLVKV-DPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----RSLFAVNKTQTSVTLLW-VEEG
EAD-FFEVFCQQAG--LNQD-----TKIQEPVTVSSHVVTISSLLPATSYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

S
SPSVPAFISVSTM--VTEMNPNVVVISVLAILSILLIGLLLVTLVV-----LRRKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPI-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPM

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRTKNR
YTNILPYDFSRVRLVTMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPVSYGDITVEMLSEEQQSDW--VFRN
FRIS--YADEVQDVMHFNYTAWPDHGVPPTNAAESILQFVQMVRQQATKSKGPMVIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQFIFIHQCVQLMWLK
KKKQFCISDVIYENVSKS-

-------------------------------------------------------MGHL-
PTR----PRGGRSLLSLLWLFVLLKNATTFHVTVQDDNSIVVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEDFNSTLPPPVTFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKHHRTAPYPPRNISVRIVNLNK-N
NWEEQSGSFPEESFIRSHEM----VGKDKLFHFADEASESPS---------GNISSGWPD
F--N-SSEEETTSQPYWWSSAPATPESEDDFVSVLPMEYENNSVLSE--TEK----SLSF
FPVQMILNWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHILSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCHKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWSRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYYNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQE-----TKLQEPIAVSSHVVTISSLLPATAYNCSVTSFSHN

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLEIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGTDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFSE---EPIAYGDITVEMISEEERDDW--ARRH
FRIN--YADETQDVMHFNYTAWPDHGVPTANAAESILQFVHVVRQQATKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWTK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
T-GIH--GA--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNISSGWPD
F--N-SSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLMVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
RGTCG--G-RRLLLLFGL--FVLMKIVATFHVTVQDDNNIVVSLEASDVVSP-ASVYVVR
VAGESKNYFFEFEPFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETRVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVGHEPKQHRTAPYPPRNISVRFVNLNK--
NWEEPSGSFPDDSFLKGQDT----IGRDRLFHFPEETPETAP---------SNVSSGWPD
L--N-GTDYESTSQPYWWDSASATPENEEDFVSVLPVDYDSDTTLGP--TEKPASDPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREE-NFTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGVCEPRKSQSAKSLSFYISPTGEWMEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTAVMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYALGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
DITSVEYYNSLLYISWTYGDDHTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMIRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVLCQQLG--SSHD-----AKLQEPIAVSSHVVTISSLRPATAYNCSVTSFSHN

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLR
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
--------PQILQRVLSSLLWFLCANASTFHVTVRDDNNIVVSLEASDIVSP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKANYHGLYYIITLVVVNGNVVSKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGSFPEESFMRSQDT----IGKDKVFHFTEETSEIPS---------GNISSGWPD
F--N-SSDYETTSQPHWWDSASATPESEDEFVSILPMEYENNSTLSE--TEKSASGSFSF
FPVQMILSWLPPKPPTAFDGFHIRIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSAKSLSFYISPSGDWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSTKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSRE-----TKLQEPIAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMVSEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANA------FVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVTKS-

-------------------------------------------------------LGKL-
SPYNF-NENNLKLDLHFLFLCFLKQDATTFHVTVRDDNSIAVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPPPIIFKANYHGLYYVITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEESGSFPEESFMRSQDT----MGKDKVFHFTDDTPEIPS---------GNISSGWPD
F--N-SSDFETTPQPYWWDSASATPESEDEFVTVLPTEYENNSTLSE--TEKSASSSFSS
FPVQMILSWLPPKPPTAFDGFHILIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRNSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWIYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRSVMTAALSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQIG--SSQE-----AKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAISTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRRKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLTKQSPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMMSEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHKVRQQAMKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSNS-

-------------------------------------------------------MGHLP
T-GIH--GG--LRLLPLLWLFVLFKNATAFHVTVQDDNNIIVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIINLNK-N
NWEEQSGNFPEESFMRSQDA----AGKEKLFHFTEETPEIPS---------GNNSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENTSTLSE--TEKSTSSSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPAGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--ASQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEERDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
-----------------P---FLKQIATTFHVTVQDDNTIVVSLEASDVVHP-ASTYIVK
IAGESKNYFFEFEEFNITLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PITSVSIYDYKPSPETGVLFEIHYPEKFNVFTRVNISYWEGKGFRTMLYKDFFKGKTVFN
HWLPGICYNNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTGDSSYFSPP----------
AKEKQTGGMSQ-------------------------------------------------
----------VFYSRYLWLAL---------------------------------------
------------A--GVSHVFCLFAHHVE-NFTEYFTVDEEAHEFEVELKEPGKYRLSVR
TFSASGSCEARKSQSAKSLSFYISSTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVLYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMVYPLGPRAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAASISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFVTAPVAP
EITSVEHINSLLYVSWTYGDDSTDLTYSRMLHWTVVAEGKKKIKKSV-TRNVMTTVLSLP
PGDIYNISVTACTERGRNTSEPRLVKL-EPVPP-----KSLFAVNKSQTSVTLLW-VEEG
IAD-FFEVLCQPLGPR--GE-----AKLQEPIAVSSHVVTISSLHPATAYNCSVTSFSHD
SPSAPTFIAVSTM--VTEMNPNIVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDLDSYIKDMGKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1304)

NRCKNR
YTNILPYDFSRVRLISINEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPITYGDITVEMVSEEEQDDW--ASRH
FRIS--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQVTRRKGPMVIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEVREVINRHFS-ISPLA
ENSRYPTSRIK-VAVST--

-------------------------------------------------------MGHLS
T-GIH--GG--RRLLPLLWLFVLFKNATPFHVTVQDDNNIVVSLETSDVISP-ASVYVVK
ITGESKNYFFEFEEFDSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSLSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCESRKSQSAKSLSFYISPSGDWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVASHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLS
S-GIH--GG--RRLLPLLWLFVLFKNATPFHVTVQDDNNIVVSLETSDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNISSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
SPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCESRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVASHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANTAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

----------------------------------------------------------IG
NPLAIDTVFHLIILLLYA---TLHQNAEPFQVTVREDNCIIVSLEASDVVSS-SSVYVVK
IAGESKNYFFQFEEFNSTLPAPVVFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPL
PVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINR-N
NWEEHSGNFPEEPFMGP-Q---KIIGKEKLSRFSGEPPVIPA---------VNTSAAWPD
YRSN-STEYEATSQPYWWPNEAESSEGEEEFVNAVPSDYEA--NE-VNTSGKLTPEPAPF
LPVQMVLTWLPPKPPTAFDGFHINIEREE-NSTEFLTVSEDTHKFVAELKEPGKYKLSVT
TFSSSGSCEVRESQSPKTLSFYISPTGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVTVTVLSSTTALTSWTASQ--
ESGGNSTIVSVVSLTCQKQKESQRLEKHYCTEVNSSNSLIENLVPGAQYQVVVYLRKGPL
VGPP

ENSGT00900000140785_8_Linker_0_1 (605, 615)

SDPVTFSI-V

PF00041 // ENSGT00900000140785_8_Domain_1 (615, 702)

PTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDP

ENSGT00900000140785_8_Linker_1_2 (702, 810)

ELSCCDSSTISFITAPVAP
EITSIEYYNHLLYVTWTYGEDGTDLSHSRMLHWMVIAEGKKKIKKSV-TRSVMTAVLSLP
PGDIYNLSVTACTERGSNSSLPQLVKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVYCQQAGSV--QE-----TKLQEPVTVSSHVVTISSLTPATSYNCSVTTFSHN
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVSTMGTVTEMNPNIVVISVLAILSILLIGLLLVTLVV-----LRRKHLQMA
RNRECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPM

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---DPIAYGDITVEMLSEEEHTDW--VYRN
FRIC--YADEVQDVMHFNYTAWPDHGVPTTNAAESILQFVQMVRQKSAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGQLP
GRAR---GG--RRLLPLLWLFVLLKNTTTFHVTVQDDNNIVVSLDTSDVASP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVTFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVHFVNLNK-N
NWEEQSGSFPEESFIKSQDS----PGKDKLFHFTDDSPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPENKDELVGVLPTEYGNHSTLSE--MEKFTSGSFAF
FPVQMILSWLPPKPPTAFDGFHILIEREE-NFTEYLTVDEEAHEFIAELKEPGKYKLSVT
TFSSAGSCETRKSQSAKSLSFYISPNGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVVYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPVTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAFLSLP
PGDIYNLSVTACTERGSNTSSPHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQIG--SSQG-----SQLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSAPAFIAVSTM--VTQMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPREYIATQGPLPETRNDFWKMVLQ
QNSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ARRH
FRIN--YADEMQNVMHFNYTAWPDHGVPTANAAESILHFVHMVRQQAAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLS
T-GIH--GG--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLETSDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
SPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------WGKL-
SQYNF-NENNLKLDLHFLFLCFLKQDATTFHVTVRDDNSIAVSLEASDIMSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPPPIIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEANFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEESGSFPEESFMRSQDT----TGKGKVFHFTDDTPEIPS---------GNISSGWPD
F--N-SSDFETTSQPYLWDSASATPESEDEFVSVLPTEYENNSTLSD--MEKSASSSFSS
FPVQMILSWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVADLKEPGKYKLSVT
TFSSSGSCETRNSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAVLSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQE-----AKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAISTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRRKHLQMA
--RECGAGTFINFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLTKQSPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMMSEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHKVRQQAMKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSNS-

--------------------------------------------------MGHLPR-GT-
-----LGGRRLLPLLGLF---VLLKIVTTFHVAVQDDNNIIVSLEASDIVSP-ASVYVVR
VAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPFPPRNISVRFVNLNK-N
NWEEPSGSFPEDSFIKP-Q---DSTGRDRLFHFPQETPETPPS---------NVSSGWPD
--PN-STDYESTSQPFWWDSASAAPENEEDFVSVLP-ADYDTEAT-LGRTEKPTADPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREE-NFTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACEIRKSQSAKSLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHILSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKKYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGGATTDLSHSRMLHWMVVAEGRKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSLLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVLCQQLGSG--HD-----GKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEVNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPMAYGDITVEMVSEEEEEDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPADAAESILQFVFTVRQQAAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
TKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXX-XXX-XXX
XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEQSGSSPEESFLRSQDV----TGKDRLFHFTEETPEIPS---------GNISSRWPD
F--N-NSDYEATSQPPWWDSASATPESEDEFVSVLPMEYEANGTVSE--TQKATTGSFSS
FPVQMILSWLPPRPPTAFDGFHIYIEREE-NFTEYLTVDEDAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLGFYISPSGEWIEELTEKPQHVSVRVLSSTKALMSWTTSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQXXXXXXXXXXXXXXXXXQVVLYLRKGPL
IGPPSDPVTFAI-V

PF00041 // ENSGT00900000140785_8_Domain_1 (615, 702)

PTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX-XX
XXXX-XXXXXXXXXXXXXXXXXXXXXX-XXX-------XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-----XXXXEPILVSSHVVTVSSLLPATAYNCSVTSFSHN
SPSVPAFIAISTM--VTEMNPNVVVISVLAILSTLLIGLLLITLII-----LRRKHLQMA
--RXXXXXXXXXXXXXXXXXXXXXXXRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLEIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1318)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQMIIMLTQCNEKRRVKCD--HYWPFTE---EPVAYGDITVEMVSEEEQDDW--AHRH
FRINYXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEAQALFIQRGHA--MTK
KEPQFCFNDFTQERVSKSC

--------------------------------------------------MGHLPR-GT-
-----LGGRRLLPLLGLF---VLLKIVTTFHVAVQDDNNIVVSLEASDIVSP-ASVYVVR
VAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFN
HWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNK-N
NWEEPSGSFPEDSFIKPPQ---DSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSAWPD
--PN-STDYESTSQPFWWDSASAAPENEEDFVSALP-ADYDTETT-LDRTEKPTADPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREE-NFTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSAKSLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSLPRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQLGSG--HN-----GKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

TPSVPTFIAVSTM--VTEVNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMVSEEEEEDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

-------------------------------------------------MVRALAKGGR-
-----STRMPLCSLLWLF---LFLKNTAPFQVTVRDDNCIVVSLEESDVVSS-SSVYVVK
ITGESKNYFFQFEEFNSTLPSPVVFNATYHGLYYIVTLLVVNSNVVSKPVRSITVLTKPL
PISSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGRDYRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKLHRTVPYPPRNISVRIVHINK-N
NWEEHSGNFPEESFLGP-Q---DIIGQEKLTHFSNDPTEIPT---------ANISYTWPD
YQDN-STDYTATSQPYWWTNEADSLENEDEFVNAVPSESENT-ST-ASISGKLTPEPPSF
LPVQMVLSWLPPKPPTAFDGFLINIEREE-NSTESLTVGEDTHEFIAELKEPGKYKLSVT
TFSSAGSCEIRRSQSAKTLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVTVLSSTTALMSWTSSQ--
DSSSNNTIVSVVSLTCQKQKQSQRLEKHYCTEVNSSNSIIENLVPGAQYQVVIYLRKGPL
VGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVILSWNRPSLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATVSLTASVKIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVSP
EITSIEYFNNLLYVSWMYGDDETDLSHSRMLHWMVIAEGKKKIKKSV-TRNMMTAVLSLP
PGDIYNLSVTACTERGSNTSAPQTVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQAGSG--QE-----TKLQEPVAVSSHVVTISSLLPATSYNCSVTTFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

S
SPSVPAFIAVSTM--VTEMNPNVVVISVLAILSILLIGLLLVTLVV-----LRRKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGIDIPHFAADLPM

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPVAYGDITVEMLSEEEQTDW--SYRN
FRVS--YADEVQDVMHFNYTAWPDHGVPPTNAAESILQFVQVVRQQSMKSKGPMVIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWLK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
PRTCG--G---RRLLPLLWFFVLLKNATAFHVSVQDDNNIVVSLEASDITNP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVSSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVGHEPKQHRTAPYPPRNISVRFVNLNK-H
NWEEQSGSFPEESFIKSQD----SAGKDKPLHLTDDAPEMPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPENEDEFVGVLPVEYGNHSTLSE--TEKSPPGSLAL
FPVQMILSWLPPKPPTAFDGFHVLIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSAKSLSFYISPSGEWMEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVVYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWSRPYLGVFRKYVVEMFYFNPVTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SGQG-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNTPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ARRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESVLQFVHVVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

--------------------------------------------------MGHLPR-GT-
-----LGGRRLLPLLWLF---VLLQIVTTLHVTVQDDNNITVSLEASDIVSP-ASVYVVR
VAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIISLVVVNGNVVTKPSRSVTVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKHHRTAPYPPRNISVRFVNLNK-N
NWEEPSGSFPEDSFIKP-Q---DSIRRDRLFHFPEETPGTPP---------SNVSSGWPD
--PN-STDYESTSQPYWWDSSSATPENEEDFVSVLPVVDYDSDTT-LSRTEKPTSDPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREE-NFTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQQVSVHVLSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKELMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
DITSVEYFNSLLYISWTYGDEHTDLSHSRMLHWMVVAEGRKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVLCQQLGSS--HD-----AKLQEPIAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSPIIVMLTQCNEKRRVKCD--HYWPFTE---EPITYGDITVEMISEDEQDDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVYMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
MRTRA--G---HRLLPLLWLFVLLKNAATFHVTVHDDNSIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVNHEPKQHRTAPYPPRNISVRFVNLNK-N
NWEEQSGNFPEESFLKSQD----STGKHKLFHFTDETPEIPS---------GNLSSGWPD
F--N-SSDYETTSQPYWWDSASATPENEDEFVSVLPIEYENNNTLSE--TEKSTASSFSF
FPVQMILSWLPPKPPTAFDGFNILIEKED-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGEPELSCCDSSTISFITAPVAP
EITSVEYFNSLLSISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSTLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQE-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---DPIAYGDITVEMISEEEQDDW--ACRH
FRIT--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLS
T-GIH--SG--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLETSDIISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
SPVQMILTWLPPKPPTAFDGFHIHMEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------LSREWG
GSRIRRLPVHLLF-FILN---IILRNAEPFQVTVREDNCIIVSLEASDVVSS-SSVYVVK
IAGESKNYFFQFEEFNSTLPAPVIFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPL
PVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINR-N
NWEEHSGNFAEESFMGQ-Q---EIMGKEKLSRFSGGPPEIPA---------VNTTAAWPD
YRSN-STEYETTSQPYLWSNEAESSEGEEEFVNAVPRDYGA--SE-VNTSGKLTAEPAPF
LPVQMVLTWLPPKPPTAFDGFHISIEREE-NSTELLTVSEDTHKFVAELKEPGKYKLSVT
TFSSSGSCEVRGSQSAKTLSFYISPTGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVTVTVLSST-TLTSWTASH--
ESGSNGTIVSVVSLTCQKQKESQRLEKHYCTEVNSSSNLIENLVPGAQYQVVVYLRKGPL
VGPP

ENSGT00900000140785_8_Linker_0_1 (605, 615)

SDPVTFSI-V

PF00041 // ENSGT00900000140785_8_Domain_1 (615, 702)

PTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATISLSASVRIANLLPAWYYNFRVTMVTWGDP

ENSGT00900000140785_8_Linker_1_2 (702, 810)

ELSCCDSSTISFITAPVAP
EITSIEYYNHLLYITWTYGGDGTDLSHSRMLHWMVIAEGKKKIKKSV-TRNVMTAMLSLP
PGDIYNLSVTACTERGSNTSLPQLVKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVYCQQAGSN--QE-----IKIQEPVTVSSHVVTISSLTPATSYNCSVTTFSHN
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVSTMDTVTEMNPNIVVISVLAILSVLLIGLLLVTLVV-----LRRKHLQMA
RNRECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPM

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---DPIAYGDITVEMLSEEEHTDW--VYRN
FRIS--YADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMVRQKSVKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLS
T-GIH--GG--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLETSDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
SPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
--------------LTSLSFFSLTQNAAPFHVTVQDDNNIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGSFPEESFLRSQDT----IGKDKLVHFTEETSEIPS---------GNISSGWPD
F--N-SSDDETTSQPYWWDSASATPESEDEFVSVAPTEELYNNCCLLNFCVKSHLSGFAV
FLLCLLFLYFPPLYPDIFSFFA---CDLE-NFTEHLTVGEEAHEFVAELKAPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
-ENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIGNLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-ERLPS-----RRLSAINHVKNGIDTLLGSGQG
HDDSFHDYLCERTDFKSKRT-----KMLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHD
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPLRALSLFSLFISVFLSSANYPFNLSFQELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVHCM--MFWSYSAVRYVVLSLGKENL---VEKSQ----DLYKP
RYLKLYTADETQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMVIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVTKS-

--------------------------------------------------MGHLPAR-A-
-----PARRRFLPLLWLF---VLLKXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEAMFNKSTLVEYSGVSHDPKQHRTAPYPPRNISVRIVNLNK-N
SWEEESGSFPEESFMRSSD---QSVGKDKLFDFPVETPEIPSG---------NIFLGWPD
FNL---SDY-TTSQPYWWDRAPATPGKGDGFVSVXXXXXXXXXXX-XXXXXXXXXXXXXX
XX--XXXXXXXXXXXXXXXXXXXXXXXXXXNFTEYVTVGEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRTSQSAKSVSFYIXXXXEWIEE

PF00041 // ENSGT00900000140785_8_Domain_0 (513, 605)

LTE-PQRVSVHILSS-TALISWTSSH--
EN-YNSTIVSVVSLTCQKQKESQRLERQYCTQVNSSKPIIENLVPGAQYQVVLYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLDPTAVVLSWTRPYLGVFRKYLVEMFYFNPTTMTS
EWTTYYEIAASVSLTASVRIAHLLPAWYYNFRVTMVTWGDPELSCCDSSTVSFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDSPHSRMLHWMVVAEGRKKIKKSX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XPAPP-----KSLFAVNQTQTSVTLLW-VEEG
IAD-FFQVFCQQIGSN--QE-----TKLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX--XTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--XXXXXXXXXXXXXXXRDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--XXX-XXXXXXXXXXXXXXXXXXXXXXXXXELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPXXXXXXXYITTHGPLPETRHDFWKMILQ
Q-SQMIIMLTQCNERRRVKCD--HYWPFTE---EPIPYGDITVEMVSEEEQDDW--ACRH
FRIS--YADEMQDVMHFNYTVWPDHGVPTANAAESILQFVHMVRQQATKSKGPLIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLLWMK
KKQQFCISDVIYENVSKS-

--------------------------------------------------MGHLPW-GT-
-----RGGRRLLPLLWLF---VLLKIVTAFHVTVQDDNNITVSLEASDIVSP-ASVYVVR
VAGESKNYFFEFEEFNNTLPPPVVFKATYHGLYYIISLVVVNGNVVTKPSRSVTVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKHHRTAPYPPRNISVRFVNLDK-N
NWEEPSGSFPEDSFIKT-Q---DSLRRDRLFHFSEETPETPP---------SNVSSGWPD
--PN-STNYESTSQPYWWDSSSATPENEEDFVSVLP-VDYDSDTT-LSRTEKPTSDPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREE-NLTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSATSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKELMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTSSVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
DITSVEYFNSLLYISWTYGDDHTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVLCQQLGSS--HD-----AKLQEPIAVSSHVVTISSLLPATAYNCSVTSFSHN

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFAFLTLLPSCLWTDYLLAFYINPWNKNGLK
KRKLT--NPV-QLDNFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVYMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLS
T-GIH--GG--RRLLPLLWLFVLFKNATPFHVTVQDDNNIVVSLETSDVISP-ASVYVVK
ITGESKNYFFEFEEFDSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSLSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCESRKSQSAKSLSFYISPSGDWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVASHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
T-RAR--GR--RRLLPLLWLFVLLKTAAAFHVTVRDDNSIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKAFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEQSGSFPEESFMRSPET----IEKDRIFHFTEETP-EPS---------GNISSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNNTLSE--AEKPTPAPFSF
FPVQMILSWLPPKPPTAFDGFHIHIEREE-NFTEYSTVDEEAHEFVAELKEPGKYKLSVT
TFSASGSCETRESQSAKSLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKRIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SGLE-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLLSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQMIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--AHRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
---------------------------TTFRVTVQDDNSIVVSLEASDVTSP-SSVYVVK
ITGESKNYFFEFEEFNGTLPPPVTFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNSNK-N
NWEEQSGSFPEESFMRSQDT----MGKDKLFRFTDETPEMPS---------GNISSGWPD
F--N-SSDYETTSQPYWWGSASTAPESEDDFVSVLPVEYEHNSTLSD--TEKSTSGPFSF
FPVQMILNWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWSRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLVYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQE-----TKLQEPISVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNW----------------------------SKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMMSEEEREDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHVVRQQATKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWTK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------

PF00102 // ENSGT00900000140785_8_Domain_3 (1137, 1304)

MVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPVAYGDITVEMVSEDEQVDW--ACRH
FRIS--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQAAKSRGPMVIHCSA
GVGRTGTFIALDRLLQHIQDHEFVDILGLVSEMRSYRMSMVQTEVGT-------------
-------------------

-------------------------------------------------------VGAI-
PVVL----LGTIHLMCLLTICVVPKNATTLHVTVQDDNSIIVSLEASDVTSP-SSVYVVK
ITGESKNYFFEFEQFNSTLPPPVIFKANYHGLYYIITLVVVNGHAVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVHIINLNK-N
NWEEQSGSFPEESFMRPHDT----MGRDKLFHFTDETPEIPS---------GNISSGWPD
V--N-SSDYETTPQPYWWDSASATPESGDGFARVLPLGYENNDTLSE--TEKPTSGSFSS
FPVQMILSWLPPKPPTAFDGFHIHIEREE-NFTEHLTVAEEAHEFVTELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWMEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTALVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATTSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SGQE-----TKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVSTM--VTVMNPNVVVISVLAILSTLLIGLLLVTLII-----LRRKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLTKQSPV-QLDDFDAYIRDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSSQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPITYGDITVEMISEEEQDDW--ACRH
FRII--YADEMQDVTHFNYTAWPDHGVPTANAAESILQFVHVVRQQATKSRGPVIVHCSA
GVGRTGTFIALDRLLQHIREHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLIWTK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLP
T-GIH--GG--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNR-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNISSGWPD
F--N-SSDYETTSQPYWWDGASAAPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLMVDEEAHEFIAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI------------------------------------------------
------------------RIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQAVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
---------------------ATASLLISFHVSVQDDNNIVVSLEASDVTNP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVSSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYT---------------------------------PYPPRNISVRFVNLNK-H
NWEEQSGSFPEESFIKSQDS----AGKDKPLHLTDDAPEMPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPENEDEFVGVLPVEYGNHSTLSE--TEKSPPGSLAL
FPVQMIMSWLPPKPPTAFDGFHVLIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSAKSLSFYISPSGEWMEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
-ENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVVYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWSRPYLGVFRKYVVEMFYFNPVTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLHLVKL-EPAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFE----------------------EPVAVSSHVVTISSLLPATAYNCSVTSFSHD
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--R---------------------------------------------------SKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1160)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNTPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRKCTDQDGMWSYLSVP---F---------LC-VSINAW------
FWLFSPKADEMQDVMHFNYTAWPDHGVPTANAAESVLQFVHVVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
-------------------------NAATFQVTVQDDNNIVVSLEASDVMNP-SSVYVVK
ITGESKNYFFEFEEFNRTLPPPVIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFFKRKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHQPKQHRTXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXXXXX-X---XXXX-XXXXXXXXXXXXXXXX---------XXXXXXXX
X--X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXPVGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVRVLSPTTALLSWTASQ--
DS-SNGTLVSVVSLTCQKQKESQRLEKQYCTQVNSSKTIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISYITXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXV-TRNVMTSILSLP
PGDIYNLSVTACTERGSNTSQLRLVKL-XXXXX-----XXXXXXXXXXXXXXXXX-XXXX
XXX-XXXXXXXXXXXX--XX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX--XPEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPXXXXXXXXXXXXXXXXXXXXXXXXXXGYNSPREYIATQGPLPETRNDFWKMVLQ
QKAQIIVMLTQCNEKRRVKCD--HYWPFTE---EPVAYGDITVEMVSEDEQDDW--ACRH
FRIS--YADDTQDVMHFNYMAWPDHGVPTANAAESILQFVHVVRQHATKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWTK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHLS
T-GIH--GG--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLETSDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNVNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
SPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

--------------------------------------------------MGHLPR-GT-
-----LGGRRLLPLLGLF---VLLKIVTTFHVAVQDDNNIVVSLEASDIVSP-ASVYVVR
VAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFN
HWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNK-N
NWEEPSGSFPEDSFIKTSQ---DSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSGWPD
--PN-STDYESTSQPFWWDSASAAPENEEDFVSVLP-ADYDTETT-LDRMEKPTADPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREE-NFTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSAKSLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCSQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTSSVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSLPRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQLSSG--HD-----GKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

TPSVPTFIAVSTM--VTEVNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMVSEEEEEDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

MLPQFAIAGHGSEPGGGRRGAAARGRGAEEPQPPPPGRSRGPRPP-RSPMPDRRRRGARG
GPGAR-----SCL-LWLF---VLLKNAEPFQVIVQEDNCIVVSLEASDVVSS-SSVYVVK
IAGESKNYFFQFEEFNSTLPAPVIFNAKYHGLYYIVTLLVVNSNMVSKSARSITVLTKPL
PVSSVSIYDYKPSPETGVLFEIQYPEKYNVFTRVNISYWEGKDYRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVRHEPKQHRTVPYPPRNISVQIVPINR-N
NWEEHSGNFAEESFMGQ-Q---EIISKEKLSRFPSDPPEIPV---------VNTTAAWPD
YRSN-STEYETTSQPYWWSNEAESSEGEEEFVNAVPRDYGA--SE-ANASGKLTAEPAPF
LPVQMVLTWLPPKPPTAFDGFHINIEREE-NSTELLTVSEDTHKFVAELKEPGKYKLSVT
TFSSSGSCEVRGSQSAKTLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVTVTVLSSTTALTSWTASH--
ESGSNGTIVSVVSLTCQKQKESQRLEKHYCTEVNSSSSLIENLVPGAQYQVVVYLRKGPL
VGPPSDPVTFSI-VPTGIKDLTLYPLGPTAVVLSWNRPFLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATISLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSIEYYNHLLYVTWTYGGDGTDLSHSRMLHWMVIAEGKKKIKKSV-TRSVMTAVLSLP
PGDIYNLSVTACTERGSNTSLPQLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVYCQQAGSN--QE-----VKVQEPVTVSSHVVTISSLTPATSYNCSVTTFSHN

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTYIAVSTM--VTEMNPNIVVISVLAILSILLIGLLLVTLVV-----LRRKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDGYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPM

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGSDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---DPIAYGDITVEMLSEEEHTDW--VYRN
FRIS--YADEVQDVMHFNYTAWPDHGVPTANAAESILQFVQMVRQKSVKSKGPMIIHCSA
GVGRTGTFIALDWLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWQK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHL-
PTR----TRGGRRLLPLLWLFVLLKNATTFHVTVQDDNNIVVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPPPVTFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGISHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----VGKDKLFHFTDETPEIPS---------GNISSGWPD
F--N-SSDYETTSQPYWWGSASATPESEDDFVSVLPMEYENNSTLSE--TEKSTAGSLSF
FPVQMILNWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSAGSCDTRKSQSAKSLSFYISPLGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWSRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQE-----TKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1315)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGTDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMVSEEERDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHVVRQQATKSKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
-------------------------NATTFHVTVQDDNNIVVSLEASDVASP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVTFKASYHGLYYIISLVVVNGNAVTKTSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEANFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVHFVNLNK-N
NWEEQSGSFPEESFIKSQDP----PGKGKIFHFTDDTPEIPS---------GNTSSGWPD
F--N-SSDFEATPQPHWWDSASTPPENEDKLVGVAPTESGNHSTLGE--TEKSTPGSFAF
FPVQMILRWLPPKPPTAFDGFHILIEREE-NFTEYQTVDEEAHEFVAELKEPGKYKLSVT
TFSSTGSCETRKSQSAKSFSFYISPAGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVLVYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPVTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTVSFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILNLP
PGDIYNLSVTACTERGSNTSSLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCEEIG--SSRG-----SQFQEPISVSSHVVTISSLLPATAYNCSVTSFSHG

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VPEMNPNVVVISVLAILSTLLIGLLLITLVI-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRSKNR
YTNILPYDFSRVRLLSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ARRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILHFVHMVRQQAAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRAYRMSMVQTEEQYIFIHQCVQLMWVK
KKQQFRISDVIYENVSKS-

------------------------------------------------------------
-------------------------------------------------MSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVNSVSIYDYKPSPETGVLFEIHYPEKYNIFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGIGHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEQSGSFPDESFMRSQDT----ME-NKLFHFTDETPEIPS---------GNISPGWPD
F--N-SNDYETTSQPYWWNSASATPESEDEFVSVVPMEYENNNTLSE--TEKSTSDSFSF
SPVQMILSWLPPKPPTAFDGFHIHIEREE-NFTEHLTVDEEAHEFVAELKEPGKYKLSVA
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSATSALMSWTSSQ--
-ESHNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWSTYYEIAATVSLTASVVIPLNQPSHVPM------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

-------------------------------------------------------MGHLS
T-GIH--GG--RRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLETSDIISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
SPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

--------------------------------------------------MGHLPR-GT-
-----RGGRRLLPLLGLF---VLIKIVTMFHVTVQDDNNIVVSLEASDIVSP-TSVYVVR
VAGESKNYFFEFEEFNNTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFN
HWLPGICYSNVTFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVHFVNLNK-N
NWEEPSGSFPEDSFIKL-Q---NPIGRDRLFHFPEETPETPP---------SNLSSGWPD
--PN-STDHESTSQPSWWDSASAAPENEEDFVSVLP-MDYDSDTA-LSRTEKPTSDPFSA
FPVQMTLSWLPPKPPTAFDGFNILIEREE-NFTDYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSAKSLSFYISPTGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
EN-YNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPEMSCCDSSTISFITAPVAP
DITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
IAD-FFEVLCQQLGSS--HD-----AKLQEPIAVSSHVVTISSLLPATAYNCSVTSFSHN

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLEREGKLPYSWRRSVFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQEDW--ASRH
FRIN--YADEAQDVMHFNYTAWPDHGVPPANAAESILQFVYMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHVRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLR
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGQL-
PTR----TRGGRRLLPLLWLFVLLKNATTFHVTVQDDNSIVISLEASDVMSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPPPITFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIINLNK-N
NWEEQSGNFPEESFMRSQDT----VGKDKLFHFTDETPEIPS---------GNISSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNNTLSE--TEKSTSGSFSF
FPVQMILSWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEDAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSVIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDTSTISFVTAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 901)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFKVFCQQVG--STQE-----TKLQEPISVSSHVVTISSLLPATAYNCSVTSFSHD

ENSGT00900000140785_8_Linker_2_3 (901, 1075)

SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDISHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMVSEEEQDDW--ACRH
FQIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHVVRQQAMKNKGPMIVHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
--------------LPSLFFSSIQQNATAFHVTVQDDNNIVVSLEASDVISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVVFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDA----TGKEKLFHFTEETPEIPS---------GNNSSGWPD
F--N-SSDYETTSQPYWWDSASATPESEDEFVSVLPMEYENNSTLSE--TEKSTSSSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVKERKRGWAHQ---SHL-----------
----------RI-VLQGNA--KEALAGSQLMVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSVLTRNVMTAFLSLP
PGDIYNPSVTACTERGSKPPCSTL--S-KPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINP-------
-------CPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLISMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEERDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVTKS-

-------------------------------------------------------MGHLP
-TRTR--GGRR--LLPLLWLFVLLKDTTTFHVTVQDDNNIVVSLEASDVVSP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKANYHGLYYIITLVVVNGNVVSKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYK----------
-----------------------------------------APYPPQNISVRIVNLNK-N
NWEEQSGSFPEESFMRSQDT----IGKDKVFHFTEETSEIPS---------GNISSGWAE
F--N-SSDYGTTSQPYWWDSASATPESEDEFVSVLPTEYN--NTLSG--MEKSTSASFSF
LPVQMILSWLPPKPPTAFDGFHIRIEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGACETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPSTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVK----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSHIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVYMVRQQATKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVTKS-

------------------------------------------------------------
-----------------FLFFLPKQNATPFHVTVQEDNSIVVSLEASDVVSS-SSVYVVK
ITGESKNYFFQFEEFNSTLPAPVVFNASYHGLYYIITLVVVNANVVIKPARSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPFPPQNISVRIISLNK-N
NWEEESGSFPEESFLRPQDL----IEKEKLLHFTDDPPEISS---------ANTSSGWPD
F--N-SSDEETTLQPYWWDSETVTPENEDEFVSVLPREDKNNNTVSL--IEKSTSAPLSF
FPVQMILNWLPPKPPTAFDGFHIHIEREE-NSTEFLTVNEEAHEFVTELNEPGKYKLSVT
TFSSSGSCETRGSQSAKTISFYISPLGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVRVNVLSSTTALMSWTSSQ--
ERDNNNTIVSVVSLTCQKQKESQRLEKHYCTQVNSSKSIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMIS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGEPELSCCDSSTISFITAPVAP
EITSVEYFNNLLYISWMYGDDTTNLSHSRMMHWMVVAEGKKKIKKSV-TRNVMTAVLNLP
PGDVYNLSVTACTERGSNTSLPHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 903)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VVD-FYKVFCHQAG--SNEE-----IKLQEPISVFSHVVTISSLLPATVYNCSVTSFSHN
SA

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAISTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKEMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVSIT--HWFSSLSLMERPSDIEQLSASLKSI--LGSWKEYFKK
YRIGYSHADEVQDVMHFNYTAWPDHGVPTTNAAESIMQFVQMVRQQSTKTRGPMIIHCSA
GVGRTGTFIALDRLLQHVCDHEYVDILGLVSDMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKRQFCISDVIYENVSKS-

------------------------------------------------------------
-MGHLPTRT-RGRLLPLLWLFVLLKNATTFHVRVQDDNSIAVSLEASDVMSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSE-TFNKSTLVEYSGVSHEPK-HRTAPYPPQNISVRIVNLNK-N
NWEEQSGSFPEEPFMRSQDT----MGKDKLFHYTDGTPEIPS---------GNISSGWPD
F--N-SSDYETASPPYWWDSASATPDSEDEFVGVLPVEYENNSTLTE--TEKSTASSFSI
FPVQMILSWLPPKPPTAFDGFHIHIEREE-NFTEYLTVGEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRNSQSAKSLSFYISPSGEWIEEL

PF00041 // ENSGT00900000140785_8_Domain_0 (514, 605)

TEKPQHVSVHVLSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLNLQ-KGPT-AVMSWARP-QGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-XXXXX-----XXXXXXXXXXXXXXXXX-XXXX
XXX-XXXXXXXXXX--XXXX-----XXXXEPVSVSSHVVTISSLLPATAYNCSVTSFSHD
SPSVPTFIAVSTM--VTEVNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEXXXXXXXXXXXXXXXXXX

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1258)

XXXXXX
XXXXXXXDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMLSEDEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQAKKSKGPMTVHC--
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------M--VTEMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADETQDVMHFNYTAWPDHGVPTANAAESVLQFVHMVRQHATKSKGPMVIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMR
KKQQFRISDVIYENVSKS-

------------------------------------------------------------
--------------LHLFLFSFIQQNATAFHVTVRDDNNIVVSLEASDIISP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNK-N
NWEEQSGNFPEESFMRSQDT----IGKEKLFHFTEETPEIPS---------GNISSGWPD
F--N-SSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSE--TEKSTSGSFSF
FPVQMILTWLPPKPPTAFDGFHIHIEREE-NFTEYLMVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDIYNLSVTACTERGSNTSMLRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQVG--SSQK-----TKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVVVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPC------
--------PV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHSGR
GST----CLLQSQLLGRLRQENHLNLEGG---ACSEPRSCHCTPEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
-------------------------DATTFHVTVQDDNNIIVSLEASDVLSP-SSVYVVK
ITGESKNYFFEFEEFNSTLPRPVTFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGQDYRTMLYKXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPYPPRNISVRIVNLNK-N
NWEEQSGSFPEESLMRSQDP----MGKDKLFHFTDKTPETPL---------GNISSGWPD
F--N-SSDYENTSQPHWWDSASATPESEDEFVSVLPTEYENNNTLSE--TEKSTSGSFAF
FPVQMILSWLPPKPPTAFDGFHIYVEREE-NFTDYLTVGEEVHEFATELKEPGKYKLSVT
TFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQ--
-ENYNSTIVSVVSLTCQKQKESQRLEKQYCTHXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXXXXXXXXXXXXPTGIKDLMLYPLGPTAVILSWTRPYLGVFRKYVVEMFYFNPATMTS
EWTTYYEIAATISLTASVRIANLLPA-YYNFRVTMVTWGXXXXXXXXXXXXXXXXXPVAP
EITSVEYFNSLLYITWTYGDDTTDLSHSRMLHWMVVAEGRKKIKKSV-TRNVMTAILSLP
AGDIYNLSVTACTERGSNTSLLHLIKL-E

PF00041 // ENSGT00900000140785_8_Domain_2 (810, 903)

PAPP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFQVFCQRVG--SNQE-----TRVQEPISVSSHVVTISSLLPATAYNCSVTSFSHD
SP

ENSGT00900000140785_8_Linker_2_3 (903, 1075)

SVPTFIAVS-M--VTEMNPNVVVISVLAILSTLLIGLLLMTLVI-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEDLKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1316)

NRCKNR
YTNILPXXXXXXXXXXXXXXXXXXXXXXXXXXGYNSPQEYIATQGPLPETRNDFWKMVLQ
QRSQIIVMLTQCNEKRRVKCD--HYWPXXXXXXXXXXXXXXXXX-------XXXXXXXXX
XXXXXXXADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQAAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLK
KKQQFCISDVIYENVSKS-

------------------------------------------------------------
-------------------------NTTTFHVTVQDDNNIVVSLDTSDVASP-ASVYVVK
ITGESKNYFFEFEEFNSTLPPPVTFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVHFVNLNK-N
NWEEQSGSFPEESFIKSQDS----PGKDKLFHFTDDSPEIPS---------GNTSSGWPD
F--N-SSDYETTSQPYWWDSASATPENKDELVGVLPTEYGNHSTLSE--MEKFTSGSFAF
FPVQMILSWLPPKPPTAFDGFHILIEREE-NFTEYLTVDEEAHEFIAELKEPGKYKLSVT
TFSSAGSCETRKSQSAKSLSFYISPNGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSPQ--
ENY-NSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVVYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPVTMTS
EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAFLSLP
PGDIYNLSVTACTERGSNTSSPHLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFEVFCQQIG--SSQG-----SQLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSAPAFIAVSTM--VTQMNPNVVVISVLAILSTLLIGLLLVTLVI-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1314)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPREYIATQGPLPETRNDFWKMVLQ
QNSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ARRH
FRIN--YADEMQNVMHFNYTAWPDHGVPTANAAESILHFVHMVRQQAAKSKGPMIIHCSA
GVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMK
KKQQFCISDVIYENVSKS-

-------------------------------------------------------MGHL-
PTRT----RGGHRLLPLLWLFVLLKNVTTFHVTVRDDNSIAVSLEDSDVMSP-SSVYVVK
ITGESKNYFFEFEEFNRTLPPPIIFKANYHGLYYIITLVVVNGNVVTKPSRSITVLTRPL
PVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFN
HWLPGICYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRIVNLNK-N
NWEEQSGSFPEESFMRSQDA----MGKDKLFHFTDDTPEIPS---------GNISSDWPD
F--N-SSDDETTSQPYWWDSASATSES-EEFVSVLPLEYENNRTLSE--TEKSTSGSFSF
FPVQMILNWLPPKPPTAFDGFHIRVEREE-NFTEYLTVDEEAHEFVAELKEPGKYKLSVT
TFSSSGSCETRNSQSAKSLSFYISPSGEWIEELTE

PF00041 // ENSGT00900000140785_8_Domain_0 (516, 605)

KPQHVSVHVLSSTTALMSWTSSQ--
-ENYNGTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKSIIENLVPGAQYQVVMYLRKGPL
IGPPSDPVTFAI-VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTS
EWTTYYEIAATVSLSASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP
EITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV-TRNVMTAILSLP
PGDVYNLSVTACTERGSNTSMFRLVKL-EPA

PF00041 // ENSGT00900000140785_8_Domain_2 (812, 900)

PP-----KSLFAVNKTQTSVTLLW-VEEG
VAD-FFQVICQQVG--SGQE-----TQLQEPISVSSHVVTISSLLPATAYNCSVTSFSH

ENSGT00900000140785_8_Linker_2_3 (900, 1075)

D
SPSVPTFIAVSTM--VTEMNPNVIVISVLAILSTLLIGLLLVTLII-----LRKKHLQMA
--RECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLK
KRKLT--NPV-QLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL

PF00102 // ENSGT00900000140785_8_Domain_3 (1075, 1231)

NRCKNR
YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
QKSQIIVMLTQCNEKRRVKCD--HYWPFTE---EPIAYGDITVEMISEEEQDDW--ACRH
FRIN--YADEMQDVMHFNYTAWPDHGVPTANAAKASCSLYTWSDSKLRRAKAP-------
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