Query Results 

MTIVDKV----SESSEPSTYQNQPGSSEAVSPGDMDASSASWGA-VSSLNDVANHTLALG
PVPGAVVYSSASVPDKSKPSPQKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELSHSTHSSPGQSSPRPVISQRVVSN-KQSASGFIGPQLPSHMIK
-NPPHVNGTG--PLKETPNSSVSSPNGNSN-VNRASPV-NASTSVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQG--Q--PNLHNNSLENPNKPVPSSTITNSSAIQSTSNAST
MSVS------SKVTKQITPGES---------------CSKPVMNGKSKLNSS------VL
VPYGAESSEESDEE-SKGLSKEN----GIGT---------VESSRSSGPD--AEEDEASQ
QE-L-----QDPVTLNGANS--TDSD----------PKENGL-PFDGASCQAQPALHSEN
PFSKANGLPGKLMPAPLPPLPEDKILE--TFKLSNKVKGSTDET----STTGIEKTPKED
HDA-GVEAGGSSTLDSSEKLEAVPSLSSKLKKALPPPSDPSIKS----------TKEEA-
SENISAKPDESLASI-NNLCNANK-DTTG-DGQLSQLCDSGD-LTNDQITPSQDIKGTLI
ESPQ-DTVSTETAEKLTPTPSVKSDDECEHKLL-VYIHREKC-KETEDLSKSKVLSA---
---NELPS---LQLDRIIG--NHSEGGTEQN--NGDRGEENKVGPK----VQDSSPIKEK
ISSLRKVDRGHYRNRRDRSSSGEHTRESKT------KTEDH--YHKKRYCYIRER----P
KQDRTKPE-HCSGSQHHPCRGERVSSCESRSLGTY--GHRHCRDG----------SGFEQ
-DWSRYHHSQSEPFWGKEKYYPDK-MRWDRCRYYHSRYT-P--YAVR-DSRDWKPFHRDR
EH----D-KGQYSGRLYKDHCESRKGYELA-AKEKGRHHFSSPRAGLPHAP-LYP-----
-----EKYSHEKTAFVSEE---TNCNLSDRFHEPENVKSRKRR--YDNIENN--DCNVEK
QARRSLQKDYLEEPKAKKHKKSKKKKKSKDKHRDRD-PRHQQDSDLSVAYSDADLHRHKK
K--KKKKKRHSRKSEDFFKDSELHLPKAAGCETVDHVQ--RPEGGAPLTG----------
--GLPLEGAGPFR--EKAKHVRMESRD-----------DQFHLPECGQGD----------
-----------------------------------

MTIVNKPKSSKSK----KSSSRRSDKSMKPRTKKMTSRTASLGR-VPPTEDPN--KVSVD
KGPGGHIYCRSS--QKSKPFAQRDLV-VN-------DGIAPPQRILFPPEKICMDWQQTQ
-SVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

VGLQNLGNTCFLNSTLQCLTYTPPLANYMLSLEHTKS--CHVEGFCMMCTMESHIN
QVLCCSNNAIKPTSVINGLKRIGKHFHFGSQEDAHEFLCFTVDALQKACLNGSTKLDRSS
QATTLIYQIFGGYLRSRVKCLNCKAVSDTYEPFLDVTLDIKAVTSVTRALEQFVKPEQLD
GENSYKCSKCKKMVPASKRYTIHRSSNVLTISLKRFANFTGGKINKDVKYPEYLDLRAYM
SQSIGEPLIYALYAVLVHSGFNCNAGHYLCFIKAGNGLWYRMNDASVELSDIKTVLNQQA
YVLFYIR-RYDLTLGERA---FYLPAPSYPRSFLGQRGANS-K--QAAFMGPRLPPHMIK
-SSNRLNGNG--PLKEDPSTVGV-------AVKRPSSA-PPTACVQNWAISRPSM---AD
PSKPQKITISIHN-KLPARPALPH-ECPSSAVEEEEL-KPLPSATVTNSSTAEPTSNLST
VSVA------TNVSKQEVPDEI---------------FVEPAVNGNPKLCCD------SM
VPYGAEPSGKPEE--SKGLFKRNCNVISSNGILLGKVVRTLHNSHSSCQN---AE-ERSQ
HEL------PKLDSLNGAIS--LDNE----------YKENGL-KLDDSTCQVQPIKPSEI
FFSKANGVL-ETMPKALSPDPQG-ILE--SLTYSQLN-SLSEEK----SVSGPQKSSDND
GVMETV-VME-ALFAYEESRKVPSNFSCEVEKLFT-Q----------SDSETIFTKEEV-
AESIITKADNAHLNI-NGQHKVRK-KSLDTEGEFLGQCESED-RDKDKLRRSKEPELISK
ENPLYIKGSPESKEKLGQTSSIKPDIECSSKKLASLDITDKCQDTKDISNNYVEVPPVND
SSI--------TKLDKVLESQFSRA----DEGLSNKICDDDDDDD-----DKHMKKNKKK
IHDSKRTDKEHYRRKRENSDTEERERQTRN------KPDDH--SHRRRSSHSVET----N
KQSRHKQE-YCSESKYRSSHNERNSPSNGRSSGKY--SRYRSRSR----------ERTDP
-DRNRYYYSKGDRPWIRERYYQDEPRRWEKCRYYNDYYS-SH---GTRDGRERRSSHCDK
DYDKLN---QAY-SRSHKDYHCKSRWAHSTLSREEDVHHFSSHRANFHHCSV--------
PQQHSEKYSRERYALPPVS-AHSNFEDSSREN--EKLRNGKRK--YSHQDES--GSDIEK
KC------RKTDDQRIKKYKKVKKKKKSKDKHREKDY--KLYDLDCSVLHFDNDNRKHKK
K---KKKKKHERKLKDLLEYLDPHFQKK---------TWEKKEESRPPDDHL-SEQYRNQ
GSKQPYKEEKPSGAGDSKKCSSMAS------------------TEYVRGVELTEE-----
---SLQYSD--------------------------

MTIVDKA----SESSEPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

RVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQHTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVISQRVVNN-KQAASGFIGPQLPSHVIK
-NPPHLNGTG--PLKETPSSSMSSPNGNSS-VNRASPV-NASTSVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQSQSQ--PNLHNNSLENSSKPAPSSTITNSSAIQSTSNTSP
VAVS------SKVTKQITPGES---------------CPKPVMNGKSKLNSS------VL
VPYGAESSEESDEE-SKGLGKEN----GLGT---------TKSSHSPGQD--AEDE-ASQ
HEL------QAPITLNGANST--DSD----------PKENGL-PFDGASCQVQPAAHSEN
PFSKANGLPVKLISAPLPPLPEDKILE--TFKLSHKAKGSAEET----R-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSTCQNQPGSSEAVSPEDMDASSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSNSSVPDKSKQSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 228)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCKCHAEGFCMMCTMQAHIT
QALNNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNK-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKPEPDKAEPSDLSICQNQPDSSEGVSSGDMDAGPASWNT-VSSLSDVPNHTLSLG
PVPGAVVYSSSSVPDKSKTSPQKDQV-VG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALNNPGDVIKPMFVMNEMRRIARHFRFGNQEDAHEFLQYTVDAMQRACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKAVSDTFDPYLDITLEIKAVQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQHNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSLDVKNG-EAAHSTH-SPSQASPRPAVGQRVVNN-KQASTGFIGPQLPSHMVK
-NPPHLNGTG--PVKDLPSSSVSSPKGN--------PV-SASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLSVSQGQVQ--P-NHSTSLEAPHEAGPPTAATSPSAATSPSAAQS
TSNG------PPAPVSMSPRES---------------CPKPMVNGKAKLGSS------VL
VPYGAESSEESDEE-SKGLAKENGVENGVGV---------MASTHCAGPE--AKDAMASP
PEI------QEPITLNGASS--TDSD----------SKENGL-SFDGASCPAQPGLHSEN
LFTKANGLPGKLIPVSLPSLPEDKVLE--TFKLNS-VKGSADET----R-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------LL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGRD--AEDEEAAP
HEI------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKLSNKLKGSTDEM----SAPGAERGPPKD
RDP-EPQLGSPA-AESLEEPDAAASLSST-KKTPP-PPDPGTPT----------TKEGA-
WEALAATPEEPPPSAG-------Q-DIA-GNTAPPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSATAEAPEGLSPAPPARSEEPCEQPLL-VHPSGDHAR-DAQDLPQSSGAPE---
-AAEGPPA---PVLEAAPA--GHLEGDAEPN--PGERGEDAA-APK----APGPSPVKEK
ISSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------AEHHPGHGDRPSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWSREKFYADR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHSRGRRGCEPA-R-ERERHRPGSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENVKSRKRR--HDSVENS--DSHVEK
KAQRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFR--RAQGGFPLPS----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCHLFEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENPTKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPMMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IVSSHSPGQD--AEDEEATP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFRLSNKLKGSTDEM----SAPGAERGPPED
RDA-EPQPGSPA-AESLEEPDAAAGLSST-KKAPP-PPDPGTPA----------TKEGA-
WEAMAVAPEEPPPSAG-------Q-DIV-GDTAPPDLCDPES-LTGDASPLSQDAKGMIA
EGPR-DSALAEAPEGLSAAPPARSEEPCEQPLL-VHPSGDHAR-DAQDRSQSLGAPE---
-AAEGPPA---PVLDMAPA--GHPEGDAEPS--PGERVEDAT-APK----APGPSPAKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------PEHHPGHGDRLSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYPDR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHNRGRRGCEPA-R-ERERHRPSSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENGKSRKRR--HDSVENS--DSHVEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSELSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRVASLETVAQFR--RAQGGFPLSG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCRLFEYGQDSTRSTEAIPSP
A----------------------------------

MTAFDKV-----ESSDPSACQNQPGSSEAVSTGDMDAGSAGWSA-VSSLSDVSNHTLSLG
PVPGA-VYSNSAIPDKSEPSPPKDQA-LG-------DGIAPPQKILFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMQRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAPSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANSTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRYCHENKLSHFL-PEAAFPSA--------------------SVLSPLL--EGQK
-NSPHLNGTG--PPKDTPSSSMSSPNGSPS-VNRPNPV-NASASVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQAQSQPNH-H-SNSLEGPNKPVPPSTVTNCSAIQSTSNTSA
-------------------IKSCS---------------KPVMNGKSKVSSS------VL
VPYGAESSEESDEE-SKGLAKEN----GMGR---------IATTHATGHE--AEEDEAPS
HEL---QE---PITLNGANS--TDSD----------PKENGL-SFEGSSCQVQPALHSEN
PFSKANGLPAKVSWGWEKK----GI-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTVLGRA-----DSSDPSARQNQPRRSEAVSIGDVDTGSASWRA-VSSLSDVFSHTLSLR
PMPSA-GYSDSAVSDRSEPSPPKDP---G-------DGIALPQKILFPSEKICLKWQQTH
-GVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 229)

GLQNLGNTCFANAALQCLTYTAPLANYMLSHEHSET--CHAEGFCMMCIMQDHIT
QALNNPGDVIKPMFVINEMQRIASHFQIGEQEDAHEFLQHTVDAMQEACLSGSNE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKV----SESSNPSACQNQPGSSVAPSLGDMDSGSASWGA-VSSLTDIPKHKISLG
PVPGAAIYSNSSISDKPKPSAQKDQS-TG-------DGIAPPQKVLFPAEKICLKWQQSH
-

PF00443 // ENSGT00890000139343_4_Domain_0 (122, 1238)

RVGAGLQNLGNTCFVNAALQCLTYTPPLANYMLSHEHSKI--XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXIAKHFRFGNQEDAHEFLRYTVDAMQKACLNGSTKLDRHS
QATTLVCQIFGGYLRSRVKCMNCKGVSDTFDPYLDIPLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFSGGKIAKXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXSHDVKNGGEHSHSIH-TPGQSSPRPVINQRVVNS-KQTVSGFIGPQLPSHMIK
-NSNHLNGTG--PLKETPSCSVASASNS--NLNRASPA-PASTSIQNWTVNRPSI--IPE
PPKKQKITISIHN-KLPVRQGQSQ--PNLHNSSLENLSKSIPSSTITNSSALQSTSNAST
MSVA------TKVSKQITPSES---------------CSKPVMNGKSKLTSS------VL
VPYGAESSEESDEE-SKGLGKEN-------------GVGILPNTCSSCQD--AEDDEASH
HEL------PETVTVNGANSI-ENSE----------PKENGL-SFDDPTCQVKPAKHSEN
PFSKTNGLHGKLMPTPLPPLPEDRIVE--SFRFSNKLRSLTDDI----SSTGNEKPPEEE
HGT-ELVIGSNSSASYEQLDKVPSSLSCKIKNPFH----PDVIA----------TKEEI-
PESIIAKPEESIPN-------ANK-KAIG-DDQFPKQCDPGN-FTDEKIKLPQEIKGTIK
ENSL-SSASVDTVEKLSQTPK---------------------------------------
-------------------------GNTEQS--NSERCEENKVRQK----VQSNSPVKEK
GGSPRKVDKGHHHNRRDHSSSGERTKQSRS------KTETH--HYKKRVSYSKER----T
KKGRHKSE-HC------PFHNESSSP-DSRSLGKH--NHYQSRSR----------GKSDQ
-ERGRYYHSKSEQSWSREKYYPEGTRRWDKYRYYNDYYL-F-------DGREWKPSHSDR
EY----DKASQYK--SHKDYYKSKWVHEPA-PKEKERHHSNSNKVDLSHGSSLP------
--QHPEKYSHDKIAL--EE---NSSNLCSQFHEHEIVKMRKRK--YDSIENN--DSDLEK
KIPKPLQNEPLEEPKVKKHKKSKKKKKSKDKHRARN--RHHQDLDLSVANSKADLRKHKK
K--KKKKKKHAKKSEDYIEHSDLRVLKASCSETIKP---------GRTQDGFPSENYPRS
N-KLSHEEDDDHP--EKTKPLRMESQD-----------HKCHPAEYGQGKGKHELRMK--
-----------------------------------

MSITEKL-----AALHISDCQNQPSRSNTSSPEDMETDCPSWHA-EPTLSDIPNHTLSLG
PVPGA-VYSNPAVPDKSESSPQKDQA-LG-------DGIAPPQEILFPSEKIYLKWQKTQ
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSRT--CHVKGFCMMCTMQAHIT
QALSHPGDVLKPMSIINEMEDVATHFHFGSQEDAHEFLQYIVDGMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFEPFLDITLEIKASPSVNKALEQFVKPEQLD
GENAYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANTTGGKIAKDVKYPEYLDIRPYM
SQQNGEPIIYVLYAVLVHAGFNCHSGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTTHSGHSPGQSSPRPVTSQRVVTN-KQAAPRFTGPQLPSHVMK
-NSPHLNGTG--PLKDTPSSSMSSPNGNPS-VSRASSV-NASTSVPNWSVNKPSV--VSE
RPKKRKIT-RIHN-KLHVRQAQSQ--SNHHNNSLEAPNKPVS-SAITNSSAIQSTSNAST
MSIS------SKVAKTLSPSES---------------CSEPVMNGNSKVSSS------ML
VPYSAESSEESDDE-FKGLAKEN----GMGR---------MTPGHSADHE--ADDDGALP
REL------PEPVTLNGANS--LDSD----------PKENGL-PLEGASCQVQPTLHSEE
PSSKARGHPEKFISATLPSLLENKV-----FKLGNKGKGSTDEI----SPPGAEKSPSGD
LAA-ELDAGSAT-AGSHEKPDSIVNLCNKFKKTLLSSVDTVISEKKLSQQTNLKSPKKAV
SENSSPKPDESLPIV-NNLCNANK-TPTG-DDQLPELCDVGN-LKRKCSEIPKEVKRLFT
ESLQ-GSAPAETVAKLRLAPSIHLESGCVHKVI-IYLGKDQCG-DAKAPFLTTGSSA---
---DLLAS---LRVS-TIG--PHPKGAHEQSHSHRERVSQGTVGEK----VPDHPPVKEK
IISLKKVDRGHYRNRRDLSSSGEQVQKSRSRS-PRSRTEDH--CHKKQHSYNRRH----R
KQQCQTLE-RCNGSQHLLCHDEWVSPAEHSSLSRY--SHHHSRSR----SRGRSKGRADQ
-DWSHSHHSDSKRAWLQEKYYTEK-IRWDRCRYYPKRYT-P--YAVRE------------
----------PSMKQPHRDSSRARKNWELS-EWVRELSTIQRLRIGATPPFPLHP-----
-----KGYPQEKVASGAVA---SSCGLSD-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPSRD--AEDEEATP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKFSNKLKGSTDEM----SAPGAERGPPED
GDP-EPQPGSPA-AESLEEPDAAASLSST-KKAPP-PPDPGTPT----------TKEGA-
WEALAAAPEEPPPGTG-------Q-DIT-GDTAPPDLCDPGS-LTGDASPLSQDAKGMIV
EGPR-DSATAEAPEGLSPAPPARSEEPCEQPLL-VHPSGDHAR-DAQDLPQSSGTPE---
-ATEGPPA---PVLEAAPA--GHLEGDAEPS--LGERGEDAA-APK----APGPSPVKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPREPD
RQDRHA-------AEHHPGHGDRPSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYADR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHSRGRRGCEPA-R-ERKRHRPGSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENVKSRKRR--HDSVENS--DSHGEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCHLFEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLALG
PVPGAVVYSSSSVPDKSKPSPQKDQA-VG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVISQRVITN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPGSSMSSPNGNSS-VNRASPV-HASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHSNSLENPTKPVPSSTITNS-AVQSTSNASM
MSVS------SKVTKPIPCSES---------------CPQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGQD--AEDEETAP
HEL------QEPMILNGANSADSNSD----------LKENGL-PPDGASCQSQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKLSNKVKGSTDET----SAPGAERGPTED
CIA-EPQPGSPA-AESLEEPDLAASLSS--TKVPP-PPDPGTPA----------TKEGT-
WEAMADAPEEPPPSAG-------Q-NIT-GDITPPDLCDPGS-LTGDPCPPSQD-MGMIV
EGPR-DSVSVEAEEGLSPAPPMGSEESHEQPLL-VHPSRDHIR-DAQDPPQSSSAPE---
-ASEGPPA---PALEAAPP--CHPVGHPEPS--SGEKGEDAAVRLK----APGPSPAKEK
IGSLRKVDRGHYRSRRERSSSGEPPRESRS------KTEGQGHRHRRHRT----CARERD
RQDRHA-------SEHHPGHGDRLSPGERRSLGRY--GHHHSRHR----------SGAEP
-DWGRHHYTEGEHSWGREKFYPDR-PRWDRCRYYHDRYASP--YA----ARDWKPFHSGR
EHERAG-----LHERPHKDHYRGRRACEPA-R-ERERHRPGSPRAGAPHTLAPHP-----
-----DRFSHDRTALVAED---NNCNLSDRFHEHESGKSRKRR--YDSLENS--DSHVEK
KSQRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDTDLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAHFR--RAQGGFPLPG----------
--GQPLEGVGPFR--EKTKHLRMESRE-----------DRCHLFEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSTYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVISQRVVNN-KQAASGFIGPQLPSHMIK
-NPPHLNGTG--PLKEAPSSSMSSPSGNSS-VSRAGSV-NASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHSSSLENPNKPVPSSTVTNSSAIQSTSSAST
TAVS------SKVTKQMTPSES---------------CSKPVMNGKSKLNSS------VL
VPYGAESSEESDEE-AKGLGKEN----GLGT---------IESSSSSVQD--AEDDEASP
LEL------REPLALNGADG--TDSD----------LQENGL-SCDGASCQVPPALHSEN
PFSKANGLPGKLMPVPLPPLPEDKILE--TFKLSNKVKGSTEET----STPGPEESPAEG
PGA-EMEAGSPS-PDPREKLETLTNLSSKLKKALP-PLDPSVKS----------TKEEV-
SENILAKPEESLPSA-NTLCSSTK-NTTG-DDVLPKLSGPGD-LMDDQSRPPQAVPGAFI
ESPR-ASAAVETVGGSSPSPPVRSEGACEHELL-VYISRDKC-TDTEDPPRSTGTAV---
---EDLPS---PQLDKMTE--NHSEGGPEQS--NSEKCEENKVGQK----IPDHSPVKEK
ISILRKVDRGHYRNRRDRSSSGERARESRS------KTEDH--YHKKRHSYLRER----A
KQDRYRTE-PCGGAQHHPCHSERLSPGEYRSLGRY--SHHHSRNR----------GGSDQ
-DWSRYHHSESEHSWGREKYYPAK-LRWDKCRYYHDRYA-Q--YTAR-ETREWKPFHSAR
DY----TKASQYGSRPSKDYYKGRKGYEPV-AKGRERHHFSPR--AAPHALLPYP-----
-----EKYPHEKIALVADD---ATCNLAERFHEHENGKSRKRR--YDSMDDS--DGHIEK
KAWRGIQKEPLEEPRAKKHKKSKKKKKSKDKHRSRD-SRHQQDSDLSVACSDADLHRHKK
K--KKKKKRHSRKSEDFVKDSEPHLPKAASHETVDRFR--RLDGTLPLTD----------
--GLPLEGVGPFR--EKRKHLRMGSRD-----------DRCPLSECGQGD----------
-----------------------------------

MTIVDKA----SESSGPSTYQNQPGSSEAVSPGDMDAGSAGWGA-VSSLNEVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

RVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRYENVLNKGEMQHSAE-SPGQSSPRPVISQRVVNNKQA-TSGFIGPQLPSHMIK
-NPPHLNGTG--PLKETPSSSVSSPNGNSN-VSRAGAV-NASTSVQNWSVNRASV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHNNGLENPTKPVPSSTITTSSAIQSTSSAP-
----------TKVTKPTAPSES---------------CSKPVMNGKSKLNSS------VL
VPYGAESSEESDEE-AKGLGREN----GLGT---------VESSNSSALD--AEADEASQ
HEL------REPVTLNGANVS-TDSD----------PEESGL-SFDGASCQVQPDLHSEN
PFSKANGLPGKLMPAPLPPLPEDKILE--TFKLGNKGKGSTDET----SAPGTDGSQTEH
PEA-GLEPGSPTPDS-REELETATGLSSKLKKASP-LPDPGIQPTS--------TKEQV-
PEGISAKPEESVPSV-NHLCNANK-NTAG-DDPLSELCDPGN-GTGEESRASQDTAGTLA
ESPR-DSAAGDATGRLSPSPAACPEGDGEQDS--VHGSRDQCTD-AEDVSKVSDVSKISG
APTDEPPS---SQLDKVTENHSEGVGAPEQS--PGEPREENKAGQK----GQARSPVKEK
ISSLRKVDRGHYRTRRDRSSSGEHARDSRS------QTEDR--YRRRRHSYTRER----T
LQG-RRPE-HCSGGPHHACE--------HRGLARH--RHHHSRSR----------GGSDH
-DWSRYHHSESEHSWGREKYYLDR-TRWDKCRYYHDRYA-P--YTAR-EAWEWRPLHGDR
DYDRDYDRVGHYGGRPYKD-YKSRKGYELG-AKERERHHLSGPRAGPPHALPPHPE----
-----K--SAERIALAPEG---SSCHLADRFHDHENVKSHKRR--YDSIEHG--DTHVEK
KAWRSVQRDPLEEPKVKKHKKSKKKKKSKDKHRERD-SRHQQDSDLSAACSDADLHRHRK
K--KKKKKRHSRKSEDCGRDSGLHLAKAASSEALDCFR--RADGSPPLTD----------
--GLPLEGAGPFR--EKTKRLRMDSRD-----------DRCHLSECGQGK----------
-----------------------------------

MTIIDKV------SSAPDACQNQLCSTVAPSSGEMENGSSVWGV-VSALA-----KIGLG
LVPAAAVYSSSSVPEKPVPSEQNDLQ-PG-------DGIDPPEKILFPPAKICLKWQRVQ
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

KVGAGLQNLGNTCFVNSVLQCLTYTAPLSNYLISREHSET--CHSQDFCMMCVMQTHIS
MALSNSGGVIKPSAVVNDLRRISKNFRYGSQEDAHEFLRYTVDEMQKSCLRGSCRLDRHT
QATTLIHQVFGGYLRSRVTCLSCKAVSDTYDQYLDLTLEIKMAHSVNQALEQFVRPEQLD
GDNAYKCSKCKQMVTASKRFTIHRTSNVLTLSLKRFASFNGGKLSKEIKYPEYLDLRPYT
SDPNGEPVIYVLYAVLIHTGFSCHGGHYYCYVKACNDQWYLMNDSTVSTTDIRTVLNQQA
YLLFYVRSQNSQSGANLYSL-H-AASPSSPQPSSSQRAGST----KSTLVGP---PRKIK
-SSKHMNGKK--S----PKNQMNNSVVNTNTVN------LKRPPLGNTVVNRQTVINIPN
-NKKQKITISINK-----YQGLPL--P--TVHKTESLNKPTPSSTITKHS------NKPT
SNTS------MALVRKHSPSKL---------------YPVPVVNGSCKAGSS------LL
VPYGADSSENSEEE-YKGL-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKV-----ESSDPAACQNQPGCSEAVSTGDMDAGSAGWSA-VSSLSDVSNHTLSLG
PVPGA-VYSNSAVPDKSEPSPPKDQA-LG-------DGIAPPQKILFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALNNPGDVIKPMFVINEMQRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAPSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANSTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELT-HSTLSPGQSSPRPVTSQRVVTN-KQAAPGFIGPQLPSHTMK
-NSPHLNGTG--PLKDTPSSSMSSPNGNPG-VSRASPV-SASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQTQSQPNH-H-SSSLEVPNKPVPPSTVTNCSAIQSTSNAST
IPVS------SKVAKPLSPSESCS---------------KPVMNGKSKMSSS------VL
VPYGAESSEESDEE-SKGLAKEN----GVGR---------MTTAHSAGHE--AEDEEAPP
HEL---QE---PVTLNGANS--TDSD----------PKENGL-SFEGASCQVQPALHSEN
PFSKANGLPGVLIPASLPSLPEDKILE--TFKLSNKVKSSTDET----SLPGTERSPSGE
LAV-ELEAGSAT-TGSHEKLDPITSLCSKFKKALL-SPDSTLKS----------TKE-VV
SENSSAKPDESLPIV-NNLCNT-K-TNSG-DDQLPELYDAGN-LTHEGSEMPQEVKGLLI
ETLQ-DSGPAETAEKLSPAPPAHSEGGCKHELL-VYLSRGESG-DAEAPSRSTGVSA---
---VTLPS---APPHRTTG--AHPEGGPE--HSLGERCSEGKAMQK----VPDHPPVKEK
ISSLRKVDRGHYRNRRDRSSSGERVQKSRSR--SRSRTEDH--CHKKRRSYTRKH----S
KQECHIME-HCNGSQHLLCYGERVSPGERRSLSRY--SYHHSRTR----------SGADQ
-DWSRYHHSDSEHAWLPEKYYPEK-MRWDRCRYHPDRYT-P--YTVR-------------
---------EPSMTRPHKDSSRARKGREPP-ARVRERTHFHSPRTGAAPSFPLHP-----
-----ERYPQEKAAFGADD---SGCGLSAS------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSTYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPEKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSAH-SPGQSSPRPVISQRVVNS-KQAASGFIGPQLPSHMMK
-NPPHLNGTG--PLKETPSSPMSGPSGNSS-VSRTGPV-SASPSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--SNLHSNSLEHPNKPAPSSTITTSSAIQSTSSAPT
PPAS------SKVPKQMAPREA---------------CSRPMMNGRPRLSAG------VL
VPYGAESSEESDEE-AKGLGQEN----GRGL---------TESACSPALD--AEDGDASP
HEL------QEPVALNGATG--LDSD----------PTENGL-PSDGAPCPGQPALHSEH
PFPKANGLPGKLMPAPLPPLPEDKILE--TFKLGSKAKGSAEET----RTPGSEERPLEH
PEA-ELEAGRSPPGDARDNLESVSNLSSKFKKASP-PSDPSIKP----------TKEEV-
SERVSAEPEEAVPSA-STFCNPDK-DALG-DDQLLAPCDPGN-LTDDQSKPSPDVGGTLP
ERPQ-DPVAAEAAGRLSPGPSVPSEGDHEPEPL-GHSGRDRG-SDAEGPSKSMGVST---
---DEAPS---AQLDTITE--NRPEGPPERS--SSERGEDSKAGQK----APEPCLVQEK
VSSLRKVDRGHYRSRRDRSSSGEHARESRS------RTEVQ--HRRKRPHREHE-R---P
RPERPRPE-PCALAPQPPCP---------SSLARS--GHHHSRSR----------GAPDQ
-EWGRYHHAEGDHAWTREKYYPDR-LRWERCRYHHDRSP-L--YPSR-EPRDWRPFHAER
EY----ERAGPYGGRPYKDHYRGRKGYELV-AKERDRHRFSSPRAGMAHAPPPHPA----
-----AKYTHDRLSFGAED---GSCDLAARFHEHDNIKSRKRR--YDSLEN---ESHVEK
KAWRSLQKDPVEEPKVKKHKKSKKKKKSKDKHRDRD-SRHQQDSDLSVAHSDADLHRHKK
K--KKKKKRHSRKSEDFGRDSEPRLPKAASCETVDHFR--KAEGAFPLAD----------
--GLPLEGAAPFC--EKTKHFRMESRE-----------VRCRLSQCDQGKGARWESGS--
-----------------------------------

MTIVDKV-----ESSDPSACQNQPGSSEAVSTGDMDAGSAGWSA-VSSLSDVSNHTLSLG
PVPGA-VYSNSAIPDKSEPSPPKDQA-LG-------DGIAPPQKILFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMQRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAPSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANSTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELT-HSTHSPGQSSPRPVISQRVVSN-KQAASGFIGPQLPSHMMK
-NSPHLNGTG--PPKDTPSSSMSSPNGSPS-VNRPNPV-NASASVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQAQSQPNH-H-SNSLEGPNKPVPPSTVTNCSAIQSTSNTSA
MSVS------SKLAKPLSPSKSCS---------------KPVMNGKSKVSSS------VL
VPYGAESSEESDEE-SKGLAKEN----GMGR---------IATTHATGHE--AEEDEAPS
HEL---QE---PITLNGANS--TDSD----------PKENGL-SFEGSSCQVQPALHSEN
PFSKANGLPAKLIPASLPSLPEDKILE--TFKLSNKVKGSTDET----SPPGTEQSQSRD
LAV-ELEAGSVT-AGSHEKLDPISSLCSKFKKALL-SPDSSLKS----------TKE-VV
SENSSAKPDESLPIV-NNLCNNDK-TSTG-SDPLPEPCDTEN-LTHNCSETPQEVKALLT
ESLQ-DSGPAETVKQLSPAPPTHLEGAHESELL-VYLSRDHCG-DTETPSRSTGESA---
---DTLPS---AQPPRTPV--AHPD-GPE--HSHGERCGEGKASQK----VPDHPPVKEK
ISSLRKVDRGHYRNRRDRSSSGEHVQKSRSR--SRSRTEGH--CHRKRHSYARKH----S
KQECHAVE-HCNGSRHPLCYGERVSPGERRSLSRY--SYHHSRTR----------SGTDQ
-DWSRYYPLDNEHSWLPEKYYAEK-MRWDRCRYYPDRYA-P--YTGR-------------
---------EPSVKRPHKDSSRARKGWEPP-ARVRERTHFHSPRTGAAPPFPLHP-----
-----ERYPQEKAAFGADD---SGCGLSDRFHEHESMKSRKHR--YESAESS--DSHVEK
KTHRSLPKD-LEEPKAKKRKKSKKKKKSKDKHQERD-YRHQLDPDLPVVYSDADLHRHKK
K-K-KKKKRHSGKSEDFAKEPGLHSPKASSYETVDHFR--RPEGSFLLTD----------
--GLAVEGIGSFR--KKTKHLRMESRA-----------DRCHLLEYGQGN----------
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSSEAVSPEDMDTGSASWGA-VSSISDVSNHTLSLG
PVPGAVVYNNSSVPEKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGETTHPAH-SPGQSSPRPGISQRVVNS-KQAAPGFIGPQLPPHVMK
-NTPHLNGTT--PVKDTPSSSVSSPNGNTS-VNRASPA-TASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQAQLNNNLHGPCLEAPSKAAPSSTITNPSAIQSTSNAPT
TS--------------VSPSES---------------CPKPMVNGKAKVGSS------VL
VPYGAESSEESDEE-SKGLAKEN----GVDM---------MTSTQSSRPETADEDGEASP
HEL------QESVMLNGANS--ADSD----------SRESSL-AFDSASCQVQPDLHTEN
LFNKLNGLPGKVTPAPLQSVPEDKILE--TFKLTNQAKGPAVEE----SWTTTGGSSPRA
SVS-QPEPITDE-TSPLEIPEAVTNGSMKTPSTT-SPLEPTISC----------TKEDSS
VVVVSAEPMEVLPSV-PALCNSTG-TTLG-DAPVPESCDPGD-LTANPSQPSQAVKGDPA
ENSE-NSTLAEVVERLSPAPSVLTGDGCEQKLF-LYLSTEGS-EEAEDSSRSSAVSA---
---DTVP----PQPDRTT---SSCAGAAEQA--AGDRGDGGSVGPK----AQEPSPAKEK
MNSLRKVDRGHYRSRRDRSSSGEHVRDSRA------RPEDH--HHKKRRCYSRERP---K
QERHPANT-YCNGGQHL-GHGDRASP-ERRSLSRY--SHHHSRVR----------SGLEQ
-DWSRYHHSENEPAWARERFYPDK-MRWDKCRYYHDRYT-TTLYTAREAAREWRPLHGRE
HE------RLVQSGRPHKDSYWGRKGWDLQ-SRGKERPHFHSPREAPGLAVPL-------
-----ERHLQEKAALSVQD---SSHSLPERFHEHESVKLRKRR--YETLDNN--DDHPEK
KVHKSLEKDALEEPRAKKHKKSKKKKKSKDKHRARD-SRHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEDFIKDVEMHLPKLSSYEAVGHFR--RTEGTFLLAD----------
--GLPVEDSGPFR--EKTKHLRMESRP-----------DRCHLSEYGQGN----------
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSSEAVSPEDMDTGSASWGA-VSSISDVSNHTLSLG
PVPGAVVYSNSSVPDKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCIMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGEPAHPAH-SPGQSSPRPGISQRVVN--KQAAPGFIGPQLPSHVMK
-NTPHLNGTT--PVKDTPSSSMSSPNGNTS-VNRASPVVNASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQAQLNNNLHGPSLEAPSKAAPSSTITNPSAIQSTSNAPM
TSVS------NKVAK------------------------SPMVNGKAKVSSS------VL
VPYGAESSEESDEE-SKGLAKEN----GVDM---------MTSTPCARPEAEEENGEASL
HEL------QESVTLNGANS--ADSD----------LRENGL-ACDSASCQVQPDLHTEN
LFSKLNGLPGKVTPAPLQTVPEDRILE--TFKLTNQAKDPSGEE----SWTTTGESPPKD
PVS-QLKPISDE-TGPLETPEAVTNGSMKIPTTMS-PMEPTINC----------TKEDS-
SIVVSANPVEALLPI-TALCDTTG-TTLG-DAPLPELCDPDD-LITTPSQPTQAAKEEVA
ENPQQGSTLAETVERLSPAPSVLTGDGCEQKLF-LYLSTEGS-EEAEDSSRSSGISA---
---DTMP----PQPDRTT---SSCEGAAEQV--TGEKDDGSKVVPK----VQEPSPAKEK
VSSLRKVDRGHYRSRRERSSSGEHARDGRA------RTEDH--HRKKRRCYSRERS---K
QERHPANI-YCNGGQHL-GHGDRASP-ERHSVSRY--SHHHSRVR----------NGPEQ
-DWSRHHHLENEHAWVRERFYPEK-IRWDKCRYYHDRYV-P--YTA----REWRPLRARE
HE------RSAQLGRPHKDSYWGRKAWESQ-PRGKERPHFHNSREAPGLALAL-------
-----ERHPQEKAVLDVQE---STHSLPERFHEHQSVKPRKRK--YATLES---DSRLEK
KPHKSLDKDTVEEPRTKKHKKSKKKKKSKDKHRDRD-GRHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEAFVKDVEMHLPKPLNYEAVSHFR--RTEGTFLLAD----------
--GLPLQDSSSFR--EKTKHLRVESRP-----------DRCYLSEYGQGKKTES------
-----------------------------------

MTTGDKA----SESSDPSTCQNQPGSSEAVSPGDMEAGSASWGT-VSSLNDVSSHALSLG
PVPGAVVYSSSPVPEKSKPSPPKDQA-LG-------DGIAPPEKILFPSEKICLKWQQTH
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

RVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXIARHFRFGSQ-DAHEFLQHTVDAMQKACLNGSN-LDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKNMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYDLYAVLVHTGFNCHAGHYFCYIKASNDLWYQMNDSIVSISDIRSVLSQQA
YVLFYIRSHDVKIGGELTHSAH-SPGQSSPQPVISQRVVSN-TQAASGFIGPQLPSHMMK
-XXXXXXXXX--XXXXXXXXXXXSPNGNSS-VSRTGPV-NASTSVQDWPVNRPSA--IPE
HPKKQKITISIHS-KLPVQKMQPQ--PTLHSSSSESANKPAPSSTITTSTAIQSTSSAPV
MPAS------SKVTKQIALRES---------------CPEPVTNGRSKLSSG------VL
VPYGAESSEESDEE-AKGLGKEN----SLRP---------AESARAPAPL--AEDVGASP
HEL------REPVALNGATS--TDSD----------PKENSL-PSGAASCHVQPALHSEN
PFSKANSLPGKLMPAPLPLLPEDKILE--TFKLGSKGKGSTDEM----STTGTEERPPQD
PEA-ELEAGSSA-PDSRENLELVMSLSSKFKKVLL-PSDASIKP----------TKEEV-
SENILAKPEEALPSTN-------K-DTL-GGDQLPKLCDPGN-LTNDQSKPSQDVKGTSP
ERPQ-DPAAAEAAGRLSPS-LVRSEGDCEPEPL-GHSSRDRGT-DVEGPPKSTGV-----
-SADGVPS---PQLDRIAE--NRPEGVPEQS--NGERGEDSKAGQK----VQEACAVQEK
TSSLRKVDRGHYRSRKDRSSSGEHARDSRS------GTEEQPRRRRPHHEWKR-CRSERR
ALR-RG-------P-HAPCP---------GSLARS--GHPRSRSM----------GAPDQ
-EWGRYHHAEAEHAWAREN-YPDG-MRWGRFRYHHDRYA-S--YPAR-EPWEWRPLHGER
EYDRAG------PYRPHKDHYRGRKGHEPA-AKERDRHRISSPGAGPAHTPPPHPA----
-----DKYAHDKAALGAED---RGCDLAGQFHEHKNIKSRKRR--YSSVGDK--DSHVEK
KAWRSLQKDPLEEPKVKKHKKSKK-KKSKDKHRERNSSRRQQYSDLLVTHSDADLHNRHK
KKKKKKKKKKHSKSENSLRDSEPLLPEATSCETVDHFQ--GADSAFPLMA----------
--SQPLDGVGPCP--EKTKHFWMETRD-----------DRCHLSKCGQGKRTYLELRI--
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSSEAVSPEDMDTGSASWGA-VSSISDVSNHTLSLG
PVPGAVVYSNSSVPEKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRAVLNQQA
YVLFYIRSHDVKNGGEPAHPAH-SPGQSSPRPGVSQRAVNS-KQAAPGFIGPQLPSHVMK
-NTPHLNGTT--PVKDTPSSSVSSPNGNTS-VNRASPA-TASTSVQNWSVTRPSV--IPD
HPKKQKITISIHN-KLPARQGQAPLNNSLHGPCLEAPSKAAPSSTITNPSAIQSTSNVPT
TS--------------TSPSEA---------------CPKPMVNGKAKVGAS------VL
VPYGAESSEESDEE-SKGLAKEN----GVDM---------MAGTHSDRPEAAADEGAEAS
SHEL-----QEPVLLNGANS--ADSD----------SRENSL-AFDSASCQVQPELHTEN
LFSKLNGLPGKVTPAPLQCVPEDRILE--TFKLTNQAKGPAGEE----SWTTTGGSSPKD
PVS-QPEPISDE-PSPLEIPEAVTNGSTQTPSTT-SPLEPTISC----------TKEDS-
SVVVSAEPVGGLPSV-SALCNSTG-TTLG-DTPVPESCDPGD-LTANPSQPTQAVKGDTA
EKAQ-DSAMAEMVERLSPAPSVLAGDGCEQKLL-LYLSAEGS-EEAEDSSRSSAVSA---
---DMMP----PKPDRTTT--SSCEGAAEQA--AGDRGDGGHVGPK----AQEPSPAKEK
MSSLRKVDRGHYRSRRERSSSGEHARDSRP------RPEDH--HHKKRHCYSRERP---K
QDRHPTNT-YCNGGQHL-GHGDRASP-ERRSLSRY--SHHHSRIR----------SGLEQ
-DWSRYHHLENEHAWVRERFYQDK-LRWDKCRYYHDRYT-P-LYTAR-DAREWRPLHGRE
HE------RLVQSGRPYKDSYWGRKGWELQ-SRGKERPHFNSPREAPSLAVPL-------
-----ERHLQEKAALSVQD---SSHSLPERFHEHESVKSRKRR--YETLENH--DGRLEK
KVHKSLEKDALEEPRVKKHKKSKKKKKSKDKHRDRE-SRHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEDFIKGVEMRLPKLSSYEAGGHFR--RTEGSFLLAD----------
--GLPVEDSGPFR--EKTKHLRMESRP-----------DRCRLSEYGQGD----------
-----------------------------------

------------------------------------------------------------
---------------------------LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPAHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IVSSHSPGQD--AEDEEATL
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPCLPEDKILE--TFRLSNKLKGSTDEM----SAPGAERGPPED
RDA-EPQPGSSA-AESLEEPDAAAGLSST-KKAPP-PPDPGTPA----------TKEGA-
WEAMAAAPEEPPPSAG-------Q-DIV-GDTAPPDLCDPGS-LTGDASPLSQNAKGMIA
EGPR-DSALAEAPEGLSPAPPARSEEPCEQPLL-VHPSGDHAR-DAQDPSQSLGAPE---
-AAEGPPA---PVLDVAPA--GHPEGDAEPS--PGERVEDAT-APK----APGPSPAKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------PEHHPGHGDRLSPGERRCLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYPDR-LRWDRCRYYHDRYV-L--YA----AREWKPFHGGR
EHERAG-----LHERPHKDHNRGRRGCEPA-R-ERERHRPSSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENGKSRKRR--HDSVENS--DSHVEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRVASLETVAQFR--RAQGGFPLSG----------
--GPPLEGVGPFR--EKTKHLRMETRD-----------DRCRLFEYGQGD----------
-----------------------------------

------------------------------------------------------------
-------------------------------------DLIPPKNIFFPPEKIFLNWQNMC
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

DIGAGLRNLGNTCYMNSVLQCLTYTAPLANYFLTCEHSKR--CVKKGFCMMCLMQKHIA
QKQYNNISIL--------SLGIAGHFKQGRQEDAHEFLRYAVDALQQACLTGYDSLDRT-
--TTFIHQVFGGYLRSEVRCLNCSGVSDTFDQFLDLQLDIKKANSVIEALKEYVRPENL-
GESCYKCSKCNKMVTATKTFSIHQPPNVLTLCLNRFDVFSENKISKMVTYPEFIDIHPYT
SEKSEGTINYRLYAVLVHAGNTCNSGHYYCYVQAPNSKWYKMNDDCVTPVDINTVLKLEA
YLLFYIR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKV----SESSNPSACQNQPGSSVAPSLGDMDSGSASWGA-VSSLTDIPKHKISLG
PVPGAAIYSNSSISDKPKPSAQKDQS-TG-------DGIAPPQKVLFPAEKICLKWQQSH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFVNAALQCLTYTPPLANYMLSHEHSKI--CHEQGFCMMCTMQAHIT
QALNNPGNVIKPMPVINDLRRIAKHFRFGNQEDAHEFLRYTVDAMQKACLNGSTKLDRHS
QATTLVCQIFGGYLRSRVKCMNCKGVSDTFDPYLDIPLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFSGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFSCHAGHYYCYIKASNGQWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGEHTHSIH-TPGQSSPRPVINQRVVNN-KQTVSGFIGPQLPPHMIK
-NSNHLNGTG--PLKETPSCSVASASNS--NLNRTSPA-SASTSIQNWTVNRPSI--IPE
PPKKQKITISIHN-KLPVRQGQSQ--PNLHNSSLENLSKSIPSSTITNSSALQSTSNAST
MSVA------TKVSKQITPSES---------------CSKPVMNGKSKLTSS------VL
VPYGAESSEESDEE-SKGLGKENGHAKPLNGLLTGN-------------D--AEDDEASH
HEL------PETVTVNGANSI-ENSE----------PKENGL-SFDDPTCQVKPAKHSEN
PFSKTNGLHGKLMPTPLPPLPEDRIVE--SFRFNNKLKSLTDDI----SSSGNEKPPEEE
LGT-ELVVGSSSSASYEQLDKVTSSLSCKIKNTFP-PSDPNVIA----------TKEEI-
TESIIAKPEESIPNI-ISHCNANK-KTIG-DDQFPKQCDPGN-FTDEKIILSQEIKGTVK
ENSL-NSAAVDTMEKLSQTPSNNFDTECDSNKLLVFISTEKCK-ETKDLSKSIDMST---
---NELSA---TQLDKIIENHYS-KGSTEQN--NSERCEENKVRQK----VQSNSPVKEK
GNSPRKADKGHHHNRRDRSSSGERTKQSRS------KTENH--YYKKRVSYSKER----T
KKSRHKSE-HCNGSKYKPFHNESSSP-DSRSLGKH--NHYQSRSR----------GKSDQ
-ERGRYYHSKSERSWSREKYYPDGVRRWDKYRYYNDYYS-Y---SSR-DGREWKPSHSDR
EY----DKASQYNNRSHKDYYKSKWVHEPA-PKEKERHHSNSNKVDLSHCSSLP------
--QHPEKYSHDKIAL--EE---NSSNLCSQFHEHDIVKMRKRK--YDSIEN---DSDLEK
KIPKPLQNEPVEEQKVKKHKKSKKKKKSKDKHRARS-CKHHQDLDLSVANSKADLRKHKK
K--KKKKKKHAKKLEDYIEHSDLHVLKASCSETDNK-IWEK-KDKSPIKDGLPSE-----
-------EDDDHP--EKTKHLRMESQD-----------HKCHPAEYGQGKTKFVFHGR--
-----------------------------------

MSITEKL-----AALHISDCQNQPSRSNTSSPEDMETDCSSWNA-EPTLSDIPNHTLSLG
PVPGA-VYSNPAVPDKSESSPQKDQA-LG-------DGIAPPQEILFPSEKIYLKWQKTQ
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSRT--CHVKGFCMMCTMQAHIT
QALSHPGDVLKPMSIINEMEDVATHFHFGSQEDAHEFLQYIVDGMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFEPFLDITLEIKASPSVNKALEQFVKPEQLD
GENAYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANTTGGKIAKDVKYPEYLDIRPYM
SQQNGEPIIYVLYAVLVHAGFNCHSGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTTHSGHSPGQSSPRPVTSQRVVTN-KQAAPRFTGPQLPSHVMK
-NSPHLNGTG--PLKDTPSSSMSSPNGNPS-VSRASSV-NASTSVPNWSVNKPSV--VSE
RPKKRKIT-RIHN-KLHVRQAQSQ--SNHHNNSLEAPNKPVS-SAITNSSAIQSTSNAST
MSIS------SKVAKTLSPSES---------------CSEPVMNGNSKVSSS------ML
VPYSAESSEESDDE-FKGLAKEN----GMGR---------MTPGHSADHE--ADDDGALP
REL------PEPVTLNGANS--LDSD----------PKENGL-PLEGASCQVQPTLHSEE
PSSKARGHPEKFISATLPSLLENKV-----FKLGNKGKGSTDEI----SPPGAEKSPSGD
LAA-ELDAGSAT-AGSHEKPDSIVNLCNKFKKTLLSSVDTVISEKKLSQQTNLKSPKKAV
SENSSPKPDESLPIV-NNLCNANK-TPTG-DDQLPELCDVGN-LKRKCSEIPKEVKRLFT
ESLQ-GSAPAETVAKLRLAPSIHLESGCVHKVI-IYLGKDQCG-DAKAPFLTTGSSA---
---DLLAS---LRVS-TIG--PHPKGAHEQSHSHRERVSQGTVGEK----VPDHPPVKEK
IISLKKVDRGHYRNRRDRSSSGEQVQKSRSRS-PRSRTEDH--CHKKQHSYNRRH----R
KQQCQTLE-RCNGSQHLLCHDERGSPAERRSLSGY--SHHHSRSRSRSRGRGRSKGRADQ
-DWSHSRHSDSKRAWLQEKYYPEK-IRWDRCRYY-KRYT-P--YAARE------------
----------PSTKRPHRDSSRPRKNWELS-EWVRELSTIQRLRVGAAGPFPLHP-----
-----EGYPQEKAASGAGA---SSCSLSDRFHEHESMKSHKRK--ISEISEI--SSPMDK
KAHRSLSKEDLEEPKAKKRKKSKKKKKSKDKHQERD-------YRLDPVYFNADLRRYKK
K--KKKKKRNSGSSEDFEETSELHSPKAINYETVYHFQ--QPEGSLL-------------
------------------------------------------------------------
-----------------------------------

MTIVDKA-----ESSGPPAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVPNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 228)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNK-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTVFGRA-----DSSDPSARQNQPRRSEAVSIGDMDTGSASWRA-VSSLSDVFSHTLSLR
PMPTA-GYSDSAVSDRSEPSPPKDP---G-------DGITLPQKILFPSEKICLKWQQTH
-GVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTAPLANYMLSHEHSET--CHAEGFCMMCIMQDHIT
QALNNPGDVIKPMFVINEMQRIASHFQIGEQEDAHEFLQHTVDAMQEACLSGSNELDRHS
QATTLICQVFGGYLRSRVQCLNCKGVSDTFDPYLDITLEIKGARTINEALAQFVKPEQLD
GENCYQCSKCKTMVTASKNFTIHQSSNVLVLSLKRFSNSTGGKIAKDVKYPEYLDIRPFT
SQPNGEPIVYTLYAVLVHAGYNCHVGHYLCHVKASNGLWYQMNDSKVSPRDTRSVLNQQA
YVLFYIRANDMKTGSEFAKHPTHRRGQSSLHRVTRPRGIAN-KQAAAGLPEPQLPPHTVK
-NSPGSKGTR--PQKDPSRSSSPSSSGSPR-VKRCGPV-NITTSVQNWS--------IPE
HPEKQKTTIGIIS-WLFSKPSL-----------FQCPCTPLNPTHVLSHFIFLMMN----
EYVK------GKLSLEKEGSQRCHEACILRGCFVCKLQMKPLLQDSASVTRL------GF
SPMGVRTCRGGA-----------------------------SSWHCAAQM--APETLSQG
AELLRVLQPSTPSFACGPKN--PAST----------LRTTNFPVGTGDRCQRQPAVP---
----AEGFPRASVSPCFPRFKELLALSGNSCCASEAPRGRREPE----NPPGTGQSPSGD
LTV-VLEAGSPT-AGSPKKLDRM-SLCSKFQKALL-PAGSSLTP----------TKE-VT
PEDSSDKLDESLPMV-NNLCHTNK-TSTG-QDPLPEPCDAVK-GTQDCSETIQEYKVLLP
SNLQ-DPSPGDTVEQLSPASSTQPEGGHEPELS-VSLSGEQCG-DIEAPSWSTGKSA---
---DALPS---AQPHGTPG--PHPDGP---RHSHGERCDKDKAGQK----APDRPAFNRK
ISSLKKTDRGRYCNHRDCSSDGEHMKRNRSRSRSQRRTGGH--WHRKRHSYTRKN----S
KQECHTAVQPRSRSRHPLCCGESVSPSKRCGLGRF--SCHHSRTR----------RGAEQ
RDRSRYHRSGSDHTWLQKTGDPKK-MRWDRYRYYPDRYT-P--YAGR-------------
---------KPSVKQPHKDSSWARKGREPP-ARVRERTHFHSPCTGAAPPFPLHP-----
-----EGHSQEKAAFGAED---SGCGLSDRFYEHKSMKSHKRR--YESAKSN--DSHKEK
KAHRSLLRD-LEEPKAKKHKRSKKKKKSKDQRQERD-HRHKE------------------
--NKKKKERHSRNSKHSKKEPGLHLLKASSHGNISYFK--RLEGSYLLTD----------
--GLPMEDTGSFP--KKSHVLAY-----------------------SQGKRRFLELLRKT
LPRFLKW----------------------------

----------------------------------MDSGSASWGP-VSSLTDGPKHIVSLG
TVNNPAIYASPSVSDKPKPSAQKDQS-TG-------DGIAPPQKVLFPAEKIFLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFVNAALQCLTYTPPLANYMLSHEHSKT--CHEQGFCMMCTMQAHIT
QALTNPGHVIKPVPIINDLRRIAKHFRFGSQEDAHEFLRYTVDAMQKACLNGSTKLDRYS
QATTLVCQIFGGYLRSRVKCMNCKGVSDTFDPYLDIPLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTVHRSSNVLTLSLKRFANFSGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFSCHAGHYFCYIKASNGQWYQMNDSIVSTSDIRAVLNQQA
YVLFYIRSYDVKNGGEHTHSIH-TPGQSSPRPVINQRVVNS-KQAGSGFIGPQLPPHMIK
QNSNHLNGNG--PLKENPSSSVASASNSN--LNRASPA--PTSTIQNWTVNRPSI--IPE
PPKKPKITISIHNNKLPVRQGQAP--ANLHNSSLETLNKPLPSSTVTNSSAIQSTSNAST
MSVA------TKVSKQIVPGES---------------CSKPVMNGDSKMNSN------LL
VPYGAESSEESDEE-SKGLGKENGLSKPFNGLLTGNGVGTLQNSSSC-QD---AEDESSQ
HEL------PETVTVNGANS--IACD----------LKENGL-VFDDSTCQVKPAIHTEN
PFSKTNGLHEKMVTAPLPLLPEDRNVE--SLRFNSKLKSPTDDI----SATGTEKTPEDG
HST-DVVTSSNNILAHEQLEKVSGSLGNKIKKAFQ-PSDPDAIG----------NKEEI-
PDSITAETEAPHPDV-GGHCSTNKRSSSSEEDPFPNVCDSGN-HTNESIGLPQEATGSAK
ENSLNAAPLVVTVANLGQTPLVDSD-QCDTNELLVLSSTEKCK-EMKDISKNKDTST---
---NELPV---AQLEKVSENHFS-KG--TEPGSSGSRCEENKVRQK----VKGHSPAKEK
TSTPQKVDKGHYRNRRGHSSSGERARQSRS------KMENH--YSKKRHSYSREG----A
KQDRYKSE-HCNGNKYRPFYNERSSPNNRRSLGKY--YHYRSRSR----------GKSEQ
-ERSRYYHSKREQSWSKEKYYPDTMRRWDKCRYYNDYYP-S--YAAR-DSRDWRAFHSDR
DYDKTS-----QYNRSHKDYYKGRWSRDPG-IKEKEKHHFSSPRINPYYCSSLHL-----
----HEKYSPEKNALVAEE---NSFNLPSQCHKHENAKERKRK--LGSVESS--ESELEK
KPRKNLQNEPLEEQKVKKHKKSKKKKKSKDKHRDKDY-----KFNMFGSCSDSEVNKYKK
K--KKKKKKHAKKSEDCTEHSDLHRVEISKLETDSNSKNQEKKESFSLKDGMPSENCQKH
NSKRPLEEDGGLL--QKAKHLGMEGQE-----------DGCHPTEFDQDSECSTEAIPNT
A----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRANPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENPTKPVPSSTITNS-AVQSTSNASM
MSVS------SKVTKPIPHSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGA---------IVSSHSPGQD--AED-EAAP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKLSNKLKGSMDEM----SAPGAERDPPED
RDA-EPQPGSPA-AESLEEPDAAASLSST-KKAPP-PPDPGTPA----------TKEGA-
WEAMAAAPEEPPPSAG-------Q-DIA-GDTAPPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSALAEAPGGLSPAPPARSEEPCEQPLL-VHPSEDHAR-DAPDPSQSSGALE---
-AAEGPPA---PVLDVAPA--GHPEWDAEPS--PGERVEDAA-APK----ALGPSPAKEK
IGSLRKVDRGHYRSRRERSSSGELARDTRS------KTE--GHRHRRRRT----CTRERD
RQDRHA-------PEYHPGHSDRLSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYSDR-PRWDRCRYYHDRYA-P--YA----AQDWKPFHGGR
EHERAG-----LHERQHKDHNRGRRSWEPA-R-ERERHRPSSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENGKSRKRR--HDSVENS--DSHVEK
KAWRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDTDLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFR--RAQGGFPVSG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCRLFEYGQGD----------
-----------------------------------

MTIVDKG----AESSDPSTCQNQPGSSEAVSPGDMDASSASWGA-VSPLNDVSNHTLSLG
PVPGAVVYSNSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKIYLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 228)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNK-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSP

PF00443 // ENSGT00890000139343_4_Domain_3 (82, 425)

QKDQ-----------------------------------
-------------------------------------------GHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDPPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLH------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPHSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGRD--AEDEEAAP
HEL------QEPMTLNGANSADSDSD----------PKENGL-LPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKLSNKLKGSTDEM----SAPGAERGPPED
GDP-EPQPGSPA-AESLEEPDAAASLSST-KKALP-PPDPGTPT----------TKEGA-
WEALAAAPEEPPPGAG-------Q-DIA-GDTAPPDLCDPGS-LTGDASPLSQDAKGMIA
EGQR-DSAMAEALEELSPAPPARSEEPCEHPLL-VHPSGDHAR-DAQDLPQSSGAPE---
-AAEGPPA---PVPEAAPA--GHSEGDAEPS--PGQRGEDAA-APK----APGPSPVKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERE
----------------------------RRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGGEKFYADR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHSRGRRGCEPA-R-ERERHRPGSPRAGAP--LAPHP-----
-----DRFFHDRTALVAG----DNCNLSDRFHEHENVKSRKRR--HDSVENS--DSHVEK
KARRSELKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAVCSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCHLFEYGQGKRRYLELRR--
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENPTKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPMMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IVSSHSPGQD--AEDEEATP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFRLSNKLKGSTDEM----SAPGAERGPPED
RDA-EPQPGSPA-AESLEEPDAAAGLSST-KKAPP-PPDPGTPA----------TKEGA-
WEAMAVAPEEPPPSAG-------Q-DIV-GDTAPPDLCDPES-LTGDASPLSQDAKGMIA
EGPR-DSALAEAPEGLSAAPPARSEEPCEQPLL-VHPSGDHAR-DAQDRSQSLGAPE---
-AAEGPPA---PVLDMAPA--GHPEGDAEPS--PGERVEDAT-APK----APGPSPAKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------PEHHPGHGDRLSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYPDR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHNRGRRGCEPA-R-ERERHRPSSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENGKSRKRR--HDSVENS--DSHVEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSELSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRVASLETVAQFR--RAQGGFPLSG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCRLFEYGQGD----------
-----------------------------------

MTIVDKV-----ESSDPSACQNQPGSSEAVSTGDMDAGSAGWSA-VSSLSDVSNHTLSLG
PVPGA-VYSNSAAPDKPEPSPPKDQA-LG-------DGIAPPQKILFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALNNPGDVIKPMFVINEMQRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAPSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANSTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELT-HSTHNPGQSSPRPVTTQRVVTN-KQTAPGFIGPQLPSHTMK
-NSPHLNGTG--PLKDTPSSSMSSPNGSTS-VNRASPV-NASTSVQNWSVNRPSV--TPE
HPKKQKITISIHN-KLPVRQALSQPNH-H-SNSLETPSKPVPPSTVTNCSAIQSTSNAST
M-------------SPLSPSESCS---------------KPVMNGKSKVSAS------VL
VPYGAESSEESDEE-SKGLAKEN----GMGR---------TASAHSAGHE--AEGDKAPP
HEL---QE---PVTLNGANS--VDSD----------PKENGL-SFEATSCQVQPALHSEN
PFSKANGLPGKLIPASLPSLPEDKILE--TFKLSNKVKGSTDET----R-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGRD--AEDEEAAP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKFSNKLKGSTDEM----SAPGAERGPPED
GDP-EPQPGSPA-AESLEEPDAAASLSST-KKAPP-PPDPGTPP----------TKEGA-
WEALAAAPEEPPPGAG-------Q-DIA-GDTVPPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSATAEAPEGLSPAPPARSEEPCEQPLL-VHPSGDHAR-DAQDLPQSSGAPE---
-ATEGPPA---PVLEAAPA--GHLEGDAEPI--PGERGEDAA-APK----APGPSPVKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------AEHHPGHGDRPSPGERRSLGGY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYADR-PRWDRCRYYHERYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHSRGRRGCEPA-R-ERKRHRPGSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENVKSRKRR--HDSVENS--DSHGEK
KARRSEQRDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFQ--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCHLFEYGQGKRRYLELRR--
-----------------------------------

-MTIVKPKSSKSK----KSSSRRSGKSKKPSAKNMKSRTANWGR-IPPAKDPN--QVSVN
QGRGGAIYCRSS--EKSKPFALRDLV-IN-------DGIAPPQRILFPPEKICMDWQQTQ
-NVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

VGLFNLGNTCFINSALQCLTYTPPLANYMLSLEHTQS--CNYQGFCMMCTMETHIN
RVLCCAHDAIKPAFVVHELKRIGKHFRFGAQEDAHEFLRFTVDAMQQACLHGCTILDRSS
QATTIIHQIFGGFLRSRVKCLNCKAVSDTYEAFLDIPLDIKTVSSVTKALEQFVKPEQLD
GENCYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKINKEVKYPEYLDLRAYM
SQSIGEPLIYALYAVLVHSGVNSHAGHYFCFIKAADGLWYQMNDASVVQSNIKTVLGQQA
YLLFYIR-RYDLTLGERA---FYLPAPSYPRSFLGQRGTNS-K--QAGFMGPRLPPHMIK
-NSSRLNGNG--SLKEDPNTVGV-------TLKRPSSA-PPTACVQNWAITRPSI---TD
PSKKQKITISIHN-KLPARQTVSQPDCLRALEEEEELNKSVPSFTVTNSSAAESTSNAST
MLFA------TNIS--EVPDEI---------------FVEPVVNGNPKLSSD------NM
VSYGTESSGKPEDESSKGLFTRNCNIISSNGILIGKVC-TLQNSYSSCQN---AEEERSK
HEL------PKNDSLNGANS--LDNE----------PKENGL-KLDDSSCQVPPVKPSEM
LFPKTNGVL-ETMPIALSPDPQEIILD--SFTYGQLN-SLSEEI----SVPGPQKSSEND
SLMETV-VME-ALLVYEESRKLPCDLSCEAGNLFI-Q----------SDSETISTKEVV-
AESIMTKADNAQLNI-NGQHKVRK-RSLDTEDEFLENFESEDSDDKDKPRRSKEPDLISK
ENPLYIKGSPETEEELGQASSIKSDVECSSKKPACLDTADKCQDTKDISNNYVEVPPVND
SSI--------TKLDKVLESQFSRE----NEGPTNRNCEENKH-----------RKKDKH
IYESKKTDKEHYRRKREHSDTEEREKQN-S------KPDGH--SHKRRCSRSVET----N
KQNRRKQD-YCNGNKYRSSYTERSSPDVSRNSGKY--SHYRSRSR----------GR-EQ
-GRNRYYHSKGERTWSRERYYQDEPWRWQKCRHYNDYYY-SH---AKGDSRERKFSHYNK
DFDRSS---QAY-SRSHKDYHYKSRRPHHSLSREEDVRHFSSHRADSRHCSV--------
PQQQSEKYSYERHILPPVL-THLRFEDSSPKNEKQSYR--KRK--YADSSES--E--TER
KS-RKIEKEVLDDEKMKKYKKVKKKKKSKDKHREKDY--K--------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_2 (126, 166)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CK

ENSGT00890000139343_4_Linker_2_3 (166, 202)

HEPWCMACTVMSNPC
--------------CGRHSFS

PF00443 // ENSGT00890000139343_4_Domain_3 (202, 425)

IARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENAAKPVPSSTITNS-AVQSTSNAST
MSVS----------------------------------SKPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGRD--AEDEEAAP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKFSNKLKGSTDEM----R-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVNKPKSSKSK----KSSSRRSGKSKKPRTKKMKSRTANWGR-IPPAEDSN--QVSVA
QGRGGAIYCRSS--EKSKPFAQRDLI-IN-------DGIAPPQRILFPPEKICMDWQQTQ
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

SVGVGLYNLGNTCFLNSTLQCLTYTPPLANYMLSLEHNQS--CREQGFCMMCTMETHIN
QALCCTVDAIKPTRVINDLRRIGKHFRFGSQEDAHEFLRYTVDAMQKACLNGSTKLDRSS
QATTIIHQIFGGFLRSRVKCLNCKAVSDTYEAFLDITLDIKAVSSVTRALELFVKPEELG
GENCYKCSKCNKMVPASKRFTIHRSSKVLTISLKRFADFTGGKINKTNNYGLFFLLIKQF
S--ATSIIKHALYAVLVHNGINCHAGHYVCYIKAGNGLWYQMNDANVVRTDIKTVLGQQA
YLLFYIRRRYDLTLGERA---FYLPAPSYPRSFLGQRGANS-K--QAGFMGPRLPPHMIK
-NSSRLNGNG--SLKEDPNTIGV-------TLKRPSSA-PPTACVQNWAITRPSI---TD
PSKKQKITISIHN-KLPARQTVSQPDCLSSAVEDEDLNKAVPSSTITNSTAAESTSNPSI
MSVT------TNVSKQEVSDEIFV----------EEIFVEPTVNENPKLSSD------NT
VPYGAESSGKSEEE-SKGLFKR-------------KVVRTLQNSHSSCQN---AEEERSQ
HEL------PKNDSLNGAIS--LVNE----------SKENGL-KLDDSTCQAEPVKPSEM
FFSKTNGLL-ETMPIAMPPVPQEVILE--SLTASQLN-SLSEEI----SVPGPQKSTEND
ALMETV-VME-ALLVYEESRKVPSDFSCEAENPFI-Q----------SDSETISTKEEV-
G-SIITKADNAHPSI-NGQHKIRS-TDLRTVETKTNQED------------------QKN
LNSFQNKESSEADEDLRQTSSLKSDSECSSKNLSSLAITDKCQDTKDISNNYVEVPPVND
SSI--------TKLDKVLESQFSRP----NEEFGDRKWEED---------AMHRKKDKKK
IHETKKTDKEHYRRKREHSDTEEKESQNRS------KTDGH--SSKRRCSRSVEV----I
KQNRHKQE-YCEGSKYRSFHSERNSPDNGRRSVKY--SKYRSRSR----------GRSEQ
-DRNRYYHSKGERTWSRERYYQDEPRRWEKCRYYNDYYS-SH---ATGDSRERKFSHGDK
DFDKLS---QAYNSRSHKDYHYKSRWPHSSLSREEDVHHFSSHRVDLHRCSV--------
PQQHSEKYSRERHALPPVS---GHFEDSPQKNEKE--RNRKRQ--YSRAEGS--ESEIER
KR-RKIEKELLGDEKMKKYKKLKKKKKSKDKHREKDY--KLYDLDFSVLHFDNDNRKRKK
K---KKKKKHIRKLKGFLE-----------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSSEAVSPEDMDTGSASWGA-VSSISDVSNHTLSLG
PVPGAVVYSNSSVPDKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCIMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGEPAHPTH-SPGQSSPRPGISQRVVNN-KQAAPGFIGPQLPSHVMK
-NTPHLNGTT--PVKDTPSSSMSSPNGNTS-VNRASPVVNASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQAQLNNNLHGPSLEAPSKAAPSSTITNPSAIQSTSNAPT
--------------KSVSPSES---------------CSKPMVNGKAKVSSS------VL
VPYGAESSEESDEE-SKGLAKEN----GVDM---------MASTPCARPEAEDADGEASP
QEL------QESVTLNGANS--ADSD----------LRENGV-AFDSASCQVQPDLHTEN
LFSKLNGLPGKVTPAPLQTVPEDRILE--TFKLTNQAKGPSGEE----SWTTTGESPPKD
PVS-QLEPISDE-TGPLETPEAVTNGNMKTPTTMS-PLEPTINC----------TKEDS-
SIVVPANPVEALPSV-TALCDTTG-TTLG-DAPLPELCDPDD-LITNQSQPTQVVKEEIA
ENPQQDSTLAEAVERLSPAPSVLTGDGCEQKLF-LYLSTEGS-EEAEDSSRSSGISA---
---DPMP----PQPDRTT---SSCEGAAEQV--TGERGDGSKVVPK----VQEPSPAKEK
VSSLRKVDRGHYRSRRERSSSGEPARDGRA------RTXXX--XXXXXX-----------
------------------XXXXXXPP-APPPTTRY--SHHHSRVR----------NGPEQ
-DWSRYHHLENEHAWVRERFYPDK-MRWDKCRYYHDRYV-P--YTA----REWRPLRARE
HE------RSAQLGRPHKDSYWGRKSWELQ-PRGKERPHFHNPREAPGLALTL-------
-----ERHPQEKAVLDVQE---STHSLPERFHEHQSVKPRKRR--YETLEN---DSRLEK
KAHKSLEKDTVEEPRTKKHKKSKKKKKSKDKHRDRD-GRHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEALMKDVEMHLPKPSNYEAVGHFR--RTEGTFLLAD----------
--GLALEDSSSFR--EKTKHLRVESRP-----------DRCYLSEYGQGD----------
-----------------------------------

----------------------------------LEEERRVQRR-ETILNELSDCTVTVP
---------DRLEGDVQQSSPEKLQS-FCEFIAINMSDLIPPKNILFPPEKIFLNWQNMC
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

DIGAGLRNLGNTCYMNSVLQCLTYTAPLANYFLTCEHSKR--CVKKGFCMMCLMQKHIA
QKQYNNISIL--------SLGIAGHFKQGRQEDAHEFLRYAVDALQQACLTGYDSLDRT-
--TTFIHQVFGGYLRSEVRCLNCSGVSDTFDQFLDLQLDIKKANSVIEALKEYVRPENL-
GESCYKCSKCNEMVTATKTFSIHQPPNVLTLCLNRFDVFSENKISKMVTYPEFIDIHPYT
SEKSEGTINYRLYAVLVHAGNTCNSGHYYCYVQAPNSKWYKMNDDCVTPVDINTVLKLEA
YLLFYIR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA-----ESSDPSTYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSNSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVISQRVVTNKQATTPGFIGPQLPSHLIK
-NPPHLNGTG--PLKETPSSSMSSPNGNPS-VNRAGPV-NASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHSNSLEAPNKPVPSSTITNSSAIQSTSNAST
MSIS------NKVAKPISPSES---------------CSKPVMNGKSKLSSS------VL
VPYGAESSEESDEE-TKGLAKEN----GVGT---------VTSSHSAGEE--AEDDEASQ
HEL------QEPITLNGANG--ADGN----------PKENGL-SFEGASCQVQPTIHSEN
PFSKANGLPGKLMPVPLPSLPEDKILE--TFKLSNKVKGSTDET----SLTGTEISPAEE
PAA-EPEVSSTTAGS-HEKVETVTSLSSKLKKALP-PSDPNTKS----------TKEEV-
SENISAKPDESLPII-NNVCHTNK-NPMG-DDQLSNLCDTEN-LTNDQSKPSQEVKGMLI
ESPR-DSAPVEIVEKLSPTPSVRSEDECEHKLL-VYLSRDRC-RDIEDPSRSTGVSA---
---DALTS---PQPDSRTTG-AHSDGGAEHS--SGERCDENKVGQK----VQDHSAVKEK
IGSLRKVDRGHYRNRRDRSSSGEHARESRS------KTEDH--YHKK-RHYVRER----A
KQERHQVE-HCNGSQHPLCHSERVSPSERRSLGRY--SYHHSRNR----------GGSDQ
-DWARHHHSESEHAWGREKYYPEK-MRWDKCRYYHDRYI-P--YAAR-EPREWRPLHSSG
RE----HD----RARLHKDCYRGRKGWEPP-ARGKERHHLHSVRVGAAPALPLHP-----
-----ARYPQEKTALGAED---SSFSLSDRFHEHETVKSRKRR--YEIIENN--DSHLEK
KAHRSLQKDPLEEPKVKKHKKSKKKKKSKDKHRERD-CRHQQDSDLSVAYSDADLHRHKK
K--KKKKKRHSRKSEDFVKDSGLHLMKAMSYETVNHFR--RTEGSFLLTD----------
--GLPLEGIGPFQ--EKTKHLRMESRA-----------DRCHLSEYGQGKRR--------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLALG
PVPGAVVYSSSSVPDKSKPSPQKDQA-VG-------DGITPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPGSSMSSPNGNSS-VNRASPV-HASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHSNSLENPTKPVPSSTITNS-AVQSTSNASM
MSVS------SKVTKPIPCSES---------------CPQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGQE--AEDEETAP
HEL------QEPMILNGANSADSDSD----------LKENGL-PPDGASCQSQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKLSNKVKGSTDET----STPGAERGPSED
YIA-EPQPGSPA-SESLEELDLAASSG-S-TKVPP-PPDPGTPT----------TKEGT-
WEAMAAASEEPPPSAG-------Q-DIITGDTAPPDLCDPGS-LTGDPSPLSQD-TGIIM
EGPR-DSVSAEAQEGLSPAPPMGSEESHEQPLL-VHPSRDHTR-DAQDPPQSSGVPE---
-ASEGLPA---PALEVAPP--GHPVGDAEPS--PGEKGEDAAVGLK----APGPSPATEK
IGSLRKVDRGHYRSRRERSSSGEPARETRS------KTEGQGHRHRRHRT----CARERD
RQDRHA-------SEHHPGHGDRLSPGERRSLGRY--GHHHSRHR----------SGAEP
-DWGRHHYAEGEHSWGREKFYPDR-PRWDRCRYYHDRYA-L--YA----ARDWKPFHSGR
EHERAG-----LHERPHKDHYRSRRGCEPA-R-ERERHRPGSPRAGAPHALAPHP-----
-----DRFSHDRTALVAED---KNCNISDRFHEHQSGKPRKRR--YDSLENS--DSHVEK
KSQRSEQKDPLEEPKVKKHKKSKKKKKSKDKHRDRDS-RHQQESDLSAACSDTDLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRASSLETVAHFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLQMESRE-----------DRCHLFEYGQGD----------
-----------------------------------

MTIVDRT-----DSSDSSDHRNQRGHSEAASTADLGAGSADQSAESSSLSDVSIHTLSLR
PVLGA-VYSESTVAG---------------------DGIPLPQKILFPPEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 229)

GLQNLGNTCFVNAALQCLTYTPPLANYMLSREHTKT--CHAGEFCVMCIMQTHII
QALSHPGDAIKPIAVISELQGIASHFQFGNQEDAHEFLQYTLDAMQEACLQGSYE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDRA----PESSDPSTYQNQPGSSDAVSPGDMDAGSASWGA-VSSLNDVANHTLSLG
PVPGAVVYSASAVPEKAKPSPQKDQX-XX-------XXXXXXXXXXXXXXXXXXXXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXD

PF00443 // ENSGT00890000139343_4_Domain_4 (348, 425)

VKYPEYLDIRPYM
SQPSGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYII----------------------------QRVANS-KQTASGFIGPQLPAHMMK
-NPPHLNGTG--PLKETPSSSISTPNGNSG-VTRAGPV-AASTSVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQGQPP--PSLHGNSLENPSKPAPSATITSPSAAQSTSSAPP
IPAA------GHTAR--QRSES---------------CPKPVVNGKSKLNSS------VL
VPYGAESSEDSDED-ARGPGREN----GVGT---------AEGARSPGQD--TEAAEAPR
HEL------HEPVTLNGAN--GADGD----------PKESGL-LCEGVGSHGQPTLNSQN
PFSKANGLPAKLPPAPLAPLPEDRVLE--TFRPSHSAKGPAEAA----SPSGAEQSPPGD
PEV-DGEAGSPT-PDSHERPEALSSLGSS-QKAPL-PSDPSPQS----------TKDVV-
SEDLSTRPVELVPSPG-------K-DTP-KDCPLSPMGDPGS-LVDSP-----EAGGVPA
GSPRTDVVTVDVEGRLSPAPPAQADGGCERQLL-FSVARDNAR-IPQPSA------S---
-TPEELPA---ALPGRITE--NHSGEALDLG--HGDQGEEDKVEQK----VPDPSPAKEK
ISSLRKVDRGHYRNWRDRSSSGERARESRS------KTEDQDRYHRRRHPYGRERERERP
RQEHPR-------TEHPPCHSDRLSPGERHLPGRCRRGHHHSRS-----------HGPEQ
-EWSRHRHSESEHAWGRGRYHPDK-LRWDRGRYYHDRYA-P--YAAR-EAWDWKPFHGDR
DYKA-G-----PPGRPHEDYHRTRKGYEPA-ARDKERHHF-SPRSGPPHAPPH-P-----
-----DRHAHEKLALAT-E---ASCHLTDRCHQPEDVKPRKRR--YESTDAA--DGHEGK
RAWRSCHKSPSQEPRAKKHKKSKKKKKSKHRARES---RCHQDSDLSVACSDVDLHRHRK
KKKK--KKRHSRRSEDFVRDPEQHLPKAVSSETVDHFR--RSEGALPLTD----------
--GLPLEGTGTSR--EKTKHLRMESRD-----------DRCHLSACGQGD----------
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSSEAVSPEDMDTGSASWGA-VSSISDVSNHTLSLG
PVPGAVVYSNSSVPEKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRAVLNQQA
YVLFYIRSHDVKNGGEPAHPAH-SPGQSSPRPGLSQRVVNN-KQAAPGFLGPQLPSHVIK
-NTPHLNGTT--PVKDTPSSSMSSPNGNTS-VKRASPA-TASTSVQNWSVNRPSV--IPD
HPKKQKITISIHN-QLPARQGQAPLSNSLHGSCLEAPSKAAPSSTITNPSAIQSTSNVPT
TS--------------ASSSEA---------------CPQPMVNGKAKVGAS------VL
VPYGAESSEESDEE-SKGLAREN----AVDM---------MAGTHSDRPEAAADDGAEAS
SHEL-----QEPVLLNGANS--ADSD----------SRENSL-AFDNASCQVQPELHTEN
LFSKLNGLPGKVTPAALQSVPEDRILE--TFKLTNQAKGPAGEE----SWTMTGGSSPKD
PVS-QPEPIRDE-PSPLEIAEAVTNGSTQTPPTT-SPLEPTISC----------TKEDP-
SVVVSAEPVEGLPSV-PALCNSTG-TTLG-DTPVPESCDPGD-LTANPSQPTQAVKGDTA
EKAQ-DSALAEVVERLSPAPSVLTGDGCEQKLL-VYLSTEGP-EEVEDSSRSLAVSG---
---DTIP----PQPDRTTT--SSCEGAAEQA--AGDR---GHVGPK----AQDPSPAKEK
MSSLRKVDRGHYRSRRDRSSSGEHVRDSRP------RPEDH--HHKKRRCYSRERP---K
QERHPANT-YCNGSQHL-GHGDRASP-ERRSLSRY--SHHHSRIR----------SGLEQ
-DWSRYHHLENEHAWIRERVYPDK-LRWDKCRYYHDRYT-P-LYMAR-DAREWRPLHGRE
HE------RLVQSGRPHKDSYWGRKGWELQ-SRGKERPHFNSPREAPGLAVPL-------
-----ERHLQEKAAMSV-D---SSHSLPERFHEHESVKSRKRR--YETLENN--DGRLEK
KVHKSLEKDSLEEPRVKKHKKSKKKKKSKDKHRDRE-SRHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEDFIKDAEMHLPKLSSYEAAGHFR--RTEGTFLLAD----------
--GLPMEDSGSFR--EKTKHLRMESRP-----------DRCHLSEYGQGN----------
-----------------------------------

MTIVDKV----SESSNPSACQNQPGSSVAPSLGDMDSGSASWGA-VSSLTDIPKHKISLG
PVPGAAIYSNSSISDKPKPSAQKDQS-TG-------DGIAPPQKVLFPAEKICLKWQQSH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFVNAALQCLTYTPPLANYMLSHEHSKI--CHEQGFCMMCTMQAHIT
QALNNPGNVIKPMPVINDLRRIAKHFRFGNQEDAHEFLRYTVDAMQKACLNGSTKLDRHS
QATTLVCQIFGGYLRSRVKCMNCKGVSDTFDPYLDIPLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFSGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFSCHAGHYYCYIKASNGQWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGEHTHSIH-TPGQSSPRPVINQRVVSS-KQTVSGFIGPQLPPHMIK
-SSNHLNGTG--PLKETPSCSVASASSS--NLNRASPA-PASTSIQNWTVNRPSI--IPE
PPKKQKITISIHN-KLPVRQGQSQ--PNLHNNSLENLSKSIPSSTITNSSALQSTSNAST
MSVA------TKVSKQITPSES---------------CSKPVMNGKSKLTSS------VL
VPYGAESSEESDEE-SKGLGKENGHAKPLNGLLTGNGVGMLPNTCSSCQD--AEDDEASH
HEL------PETVTVNGANSI-ENSD----------PKENGL-SFDDPTCQVKPAKHSEN
PFSKTNGLHGKLMPTPLPPLPEDRIVE--SFRFSNKLKSLTDDI----SSTGNEKSPE-E
HGT-ELVVGSNSSASFEQLEKVTSSLSCKIKNNFP-PSDPNVIA----------TKEEI-
PESIIAKTEESIPNV-ISHCNANK-KAIG-DDQFPKQCDPGN-FTDEKLLLSQEVKGTLK
ENSL-NSAPVDTVEKLSQTPSNNFDTECDSNKLLVFISTEKCK-ETKDLSKSIDMSA---
---NELSA---TQLDKIVENHYS-KGSTEQS--NSERCEESKVRQK----VQSNSPVKEK
GDSPRKVDRGHHHNRREHSSSGERTKQSRS------KTETH--YYKKRVSYSKER----T
KKGRHKSE-HCNGSKYKPFHNESSSP-DSRSLGKH--NHYRSRSR----------GKSDQ
-ERGRYYHSKSERSWSREKYYPDGMRRWDKYRYYSDYYP-Y---SSR-EGREWKPSHSDR
EY----DKASQYNSRSHKDYYKSKWVHEPA-PKEKERHHLNSNKVDLSHCSSLP------
--QHPEKYSHDKIAL--E----NSSNLCSQFHEYESVKMRKRK--YDSIENS--DSDIEK
KIPKPLQNEPVEEQKVKKHKKSKKKKKSKDKHRARS-CKHHQELDLSVVNSKADLRKHKK
K--KKKKKKHAKKSEDYIEHSDLHVLKISCSETDNK-TWEK-KDKSPIKDGLPSEDYQKF
N-KLSHEEDDDHP--EKTKHLRMESQD-----------HKCHPAEYGQAKGLPSHKDYSQ
KVSSKQLDDSSTSTDESRWKVNENSSSKEKIH---

MTIVDKA----SESSDPSTYQNQPGSSEAVSPGDMDAGAASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-

PF00443 // ENSGT00890000139343_4_Domain_2 (122, 159)

RVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXSHDGKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAASGFIGPQLPSHLIK
-NPPHLNGTG--PLKDTPSSSVSSPNGNSN-VNRASPV-NASTSVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--SNLHSSSLENTNKPVPSSTITNSSAIQSTSNAST
MSVS------SKVTKPITTSES---------------CSTPVMNGKSKLNSS------VL
VPYGAESSEXXXXX-XXXXXXXXXXXXXXXX---------XXXXXXXXXX----XXXXXX
XXX------XXXXXXXXXXX--XX-X----------XXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX----XXXXXXXX-XXX
XXX-XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX------------XXX-
XXXXXX---XXXXXX-XXXXX--X-XXXX-XXXXXXXXXXXX-XXXXX--XXXXXXXXXX
XXXX-XXXXXXXXXXXX-X-XXXXXXXXXXXXX-XXXX--XX-XXXXXXXXXXXXXXXXX
XXXXXXXXPPSLQLDRTTG--THLEEGTEQS--NGERYDESRAGQK----AQDHSPVKEK
ISSLRKVDRGHYRNRRDRSSSGEHARESRS------KTEDR--YHKKRRSYVRERA---K
QDGH--------LAEHHPCHRERASPGERHSLGRY--SHHHSRNR----------SGSEQ
-DWSRYHHSESEHAWGREKYYLEK-MRWDKCRYYHDRYA-P--YAAR-EVREWKPFHGGR
EH----DRVGQYNSRSYKDYYIGRKGYELA-SKEKERHHFSSLRVGPAHTFPSYP-----
-----EKYPQEQMILAAED---HSCNLPDRFHDHENAKSRKRR--YNSFENN--DGYLEK
KAQRSLQKDLLEEPRMKKHKKSKKKKKSKDKHRDRE-SRHQQDSDLSAVYSDADLHRHKK
K--KKKKKRHSRKSEDFVKDSELHLPKATSYETVDHFR--RTEGGFLLTD----------
--GLPLEGVGPFR--EKTKHFRMESRD-----------DRCHLSEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSNSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVISQRVVNN-KQAASGFIGPQLPSHMIK
-NPPHLNGTG--PLKEAPSSSMSSPSGNSS-VSRAGSV-NASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHSGSLENPTKPVPSSTITNSSAIQPTSSVPT
TAVS------SKVTKQMPPSES---------------CSQPVMNGKSKLSSS------VL
VPYGAESSEESDEE-AKGLGKEN----GLGA---------TESSDSPVQG--AGDDEACP
LEL------REPLALNGADS--TDSD----------LKENGL-PCDGASCQVPPTLHSEN
PFSKANGLPGKLMPAPLPPLPEDKILE--TFKLSNKVKGSTEET----SAPGTEEGPADD
PGM-ELEPGSPS-PESHEKPETLTSLSSKLKKALP-PLDPSVKS----------TKEEV-
SENILAKPEESLPSA-NTLCSSTK-NTVG-DDPLPKLCSPGD-LTDDQSRPPQAGSGVLL
ESPR-ASAAVEAAGSSSPSAPVHSEDACEHELL-VYISRDTC-SDLEDPPRSGGAAA---
---EGLPS---PQADKITE--NHSEGGPEQS--NGEKCEENMVGQK----VPDHSPVKEK
ISILRKVDRGHYRNRRDRSSSGERARESRS------KTEER--YHKKRRSSVRERG---P
KQDRYRTE-HGSGGQHHLCHGERLSPGEHRSLGRY--GHHHSRGR----------GGSDQ
-EWSRHHHPEGEHSWAREKYYPDR-LRWDKCRHYHDRYA-L--YAAR-EVREWRPFPGAR
EY----AKAGPSGGRPYKDYYRGRKGHELL-AKGKDRHRFGSPRAGPPHALLPYP-----
-----DKYPHEKIALVAED---TNCNLADRFHEHENAKSRKRR--YDSLENS--DGHLER
KAWRGFQKDPLEEPKVKKHKKSKKKKKSKDKHRGRD-SRHQQDSDLSVACSDADLHRHKK
K--KKKKKRHSRKSEDFVKDSEPHLPKAVSHETVDRFR--RTDGAFPLTD----------
--GLPLEGAGPFR--EKRKHLRMGSRD-----------DRGPLSECGQGD----------
-----------------------------------

MTIVDKA----SESSDPSAYQNPPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVSDKSKPSPQKDQX-XX-------XXXXXXXXXXXXXXXXXXXXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XHA

PF00443 // ENSGT00890000139343_4_Domain_3 (167, 425)

EGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELPHATH-SPGQSSPRPLLSQRGVSS-KQATPGFIGPQLPSHMLK
-NPPQLNGTG--PLKDTPSSCMSSPSGSSS-VNRASPV-HASTSVPSWSVNRSSV--TAE
HPKKQKITISLHN-KLPVCQGPPP--AGLHGSPSESPSKPGPCSTVSTPAAQ-PTSNAAA
-PAC------GAGPKPAAPAAA---------------CSAPMVNGSAQLGPG------VL
VPYAAESSEESDEE-PKGLRREN----GVGG---------GLAENSPPAR--AEAGQ--P
SLP------QEP--VSGAN--GADGE----------PTGNGL-SVDGASCQGPVAAPAES
AFAKANGLPGKLTPAPLPSLPEDEILE--TCTLNSKAKGAAGET----RAPAVEST-SED
PTA-EPEPGGSA-TGDMGQA--AGLVGSS-RKALP-PSDPGGAP----------TKEGP-
DEASAAAKE-PVPGAS---------EPAAGD-----TALPRT-MAAAPGPLPQEVTGPLA
GSPS-DPAPLERAAELSPVPTASAEAACERTLS-VHLSGDRGC-DPQGCPPAQ-------
-------------PARTAG--SQPEGGSRQS--RGERGEEAKV-GT----ALERSPGKER
VGGPRKVDRGHYRTWRDRSSSGEHAWESRG------KTPEHRH---RERH----CGRERA
RPERHP-------A-EPCGAQHPLSPGDRHSLGTY--GHHHSRPR----------SASAQ
-GWSRCHPSESEHTWARGKYYPDR-MRWDRCRYYHDRYA-P--YA----ARDWKPFHSGR
SCRHYR-----WSSRGSETL---------A-R-DRQRHHAHGTRTHPP------------
--------GSEKVAQVSHD---GAASLAERFHEHEELRPRRRYGSVDGDRSR--DSHAAR
KAPRSPQRDLVEEPKAKKHKKSKKKKKSKDKHRERDC-RHQ-DSDLAGANSDADLHRHRK
KKKK--KKRRSRRSRDLAKAPGRGLPKATSCETGDRWH--RAEGSFPLAA----------
--ALPGESLGPFR--EKAQQLRLEGRA-----------SRCRLSEHGQGD----------
-----------------------------------

MTIVDKT-----EPSDPSSCQNQPGSSEAVSPEDMDTGSASWGA-VSSISDVSNHTLSLG
PVPGAVVYSNSSVPDKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCIMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENAYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGEPTHPTH-SPGQSSPRPGISQRVVNN-KQAAPGFIGPQLPSHVMK
-NTPHLNGTS--PVKDTPSSSMSSPNGNTS-VNRASPV-NASTSVQSWSVSRPSV--IPE
HPKKQKITISIHN-KLPVRQGQAQLNNNLHGPSLEAPSKAAPSSTVTNSSAIQSTSNAPV
T--------------SVSPSES---------------CSKPMVNGKAKVSSS------VL
VPYGAESSEESDEE-SKGLAKEN----GVDL---------MASTPCARPEAEDEDGEASP
HEL------QEPVTLNGANS--ADSD----------LRENGL-AFDSTSCQVQPDLHTEN
LFSKLNGLPGKVTPAPLQSVPEDRILE--TFKLTNQAKGPLGEE----SWTTTRESPPKD
PVS-QLEPISDE-TGPFETPEAVTNGSMKTPTTMS-PLEPTIDC----------TKEDS-
SIVVSANPVEALPSI-TALCNTTG-TTLG-DGPPPELCDPDD-LTTSPSQPTQAVKGEIA
ENPQ-DSTVAEAVERLSPAPSVLTGDGGEQKLF-LYLSTEGS-EEAEDSSRSSGISA---
---DTVP----PQPDRTT---SSCEGAAEQV--TGDRGDGSKVGPK----VQEPSPAKEK
MSSLRKVDRGHYRSRRERSSSGEHARDGRA------RAEDH--HHKKRRCHSRERP---T
QERRPANP-HCNGGQHP-GHGDRASP-ERRSLSRY--SHHHSRVR----------NGPEQ
-DWSRYHHLENEHAWVRERFYPDK-MRWDKCRYYHDRYT-P--YTA----REWRPLRGRE
HE------RTAQPGRPHKDSYWGRKGWEPQ-PRGKERPHFHSPREAPGLALPL-------
-----ERHPQEKAVLDMQE---SSHSLPERFHEHESVKSRKRR--YETLENV--DSRLEK
KAHKNLEKDTLEEPRVKKHKKSKKKKKSKDKHRDRD-GRHQQESDFSGAYSDTDLHRHRK
K--KKKKKRHSRKSEDLMKDVEMHLPKSSSYEAVGHFR--RTEGTFLLAD----------
--GLPVEDSGSLR--EKTKHLRMESRP-----------DRCHLSEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLALG
PVPGAVVYSSSSVPDKSKPSPQKDQA-VG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVISQRVITN-KQTAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPGSSISSPNGNSS-VNRASPV-HASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNASM
MSVS------SKVTKPIPCSES---------------CPQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGA---------IASSHCPGQD--AEDEETTP
HEL------QEPMILNGANSADSDSD----------LKENGL-PPDGASCQSQPALHSEN
PFAKANGLPGKLIPAPLPSLPEDKILE--TFKLSNKVKGSTDET----SAPGAERGPSED
CIA-EPQPGSPA-AESLEEPDLAASLSS--TKVPP-PPDPGTPA----------TKEGT-
WEAMAAAPEEPPPSTG-------Q-DIITGDTMPPDLCDPGS-LTGAPSPLSQD-TGMIV
EGPR-DSISAEAQEALSPAPPMGSEESHEQPLL-VHPSRDHTR-DAQDPPQSSGAPE---
-ASEGPPA---PALEAALP--GNPVGDPEPS--PGEKGEDAAVGPK----APGPSSAKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTEGQGHRHRRHRT----CARERD
RQDRHA-------SEHHPGHGDRLSPGERRSLGRY--GHHHSRHR----------SGAEP
-DWSRHHYAEGEHSWGREKFYPDR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHSGR
EHERAG-----LHERPHKDHYRGRRGCEPA-R-ERERHRPGSPRTGAPHAPTPHP-----
-----DHFSHDRTALVAE----DNCNLSDRFHEHESGKSRKRR--YNSLENS--DSHVEK
KSQRSEQKDPLEEPKVKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDTDLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAHFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLRMESRE-----------DRCHLFEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDPPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGRD--AEDEEAAP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGIPGKLMPAPLPSLPEDKILE--TFKFSNKLKGSTDEM----SAPGAERGPPED
GDP-EPQPGSPA-AESLEEPDAAASLSST-KKAPP-PPDPGTPT----------TKEGA-
WEALAAAPEEPPPGAG-------Q-DIA-GDTAPPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSATAEAPEGLSPAPPARSEEPCEQPLL-VHPSGDHAR-DAQDLPQSSGAPE---
-ATEGPPA---PVLEAAPA--GHLEGDAEPS--PGERGEDAA-ALK----APGPSPVREK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------AEHHPGHGDRPSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYADR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHSRGRRGCEPA-R-ERERHRPGSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENVKSRKRR--HDSVENS--DSHVEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCHLFEYGQGD----------
-----------------------------------

------------------------------------------------------------
---------------------------LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGDLTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------ML
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IVSSHSPGQD--AEDEEASP
HEL------QEPVTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFKLSNKLKGSTDET----SAPGAERGPPED
RDA-EPQPGSPA-AESLEEPDAAASLSSS-KKAPP-PPDPGTPA----------TKEGA-
WEAMAAASEEPPPSAG-------Q-DIA-GDTALPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSALTEAPEGLSPAPPAQSEEPCQQPLV-VHPSGDHAW-DAQDPSQSSGVPE---
-AAEEPPA---PVLDVAPA--GHPEGDAEPS--PGEMVEDAA-APK----APGPSPAKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------PEHHPGHGDRLSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYPDR-PRWDRCRYYHDRYAAP--YA----ARDWKSFHGGR
EHERAG-----LHERPHKDYNRGRRGCEPA-R-ERERHRPSSPRAGAPHALAPHP-----
-----DRFSHDRTALVAA----DNCNLSDRFHEHENGKSRKRR--RDSVENS--DSHVEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAVCSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRVASLETVAQFR--RAQGGFPLSG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCRLFEYGQGD----------
-----------------------------------

MTIVDKN----SESSDPSACQNQPGSSEAVSTGDMDASSASWGP-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKQSPQKDQA-PG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCIMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTFVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQTVNKALEQFVKPEQLD
GENAYKCSKCKKMVTASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGSELAHSTH-SPGQSSPRPVISQRVVSNNKQASAGFIGPQLPSHVMK
-NPPHLNGTG--PLKDTPSSSLSSPNGNSS-VNRTSPV-NASTSVQNWSVNRPSV--MPE
HPKKQKITISIHN-KLPGRQGPSQ--PNLHSNSLENPNKSVPSSTITNSSAIPSTSTAST
MSIS------SKITKTATLSEA---------------CSKPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GVGA---------ISDSLAPGQGA--EDEEV-S
QHEL-----QEPITLNGANS--ADSD----------LKENGL-PFDGADCQVQPALHSEN
PFSKANGLPGKSMPALLPSLPEDKILE--TFKLNT-VKGSTDET----STPGIEKNPPKD
HDV-ELKAGGPT-ADSHEKLEMVTSLSTKLKKALP-PPDPSVNS----------TKEEV-
SENSSAKPDDILCNTN-------K-NTVG-DDQFSKLCDPGD-LTDEQSKPSQDVKGALV
ESPR-DLVSVETVEKLSPVPSVHSEDECEQQLL-VYLSRDRC-KDVEDLSKTVGVPA---
---DRLPS---PQLDRTIG--NPSDGATEQS--HGDRGDESKVGQ----NVQDHSPIKEK
ISSLRKVDRGHYRNRRDRSSSGEHAKESRS------KTDDR--YYKKHRSYVRERP---R
QDRYTTEY-CNGSQHHLSHSER-VSPGEHHSLSRY--SYHHSRNR----------SGSDQ
-DWIRYHHVEGEHIWGREKYYPDK-MRWDKCRYYHDRYA-P--YTAR-EAREWKPFLNSR
EP----DRAGQRHGQLHKDYYRSRKGYEVT-AKDKPRHHLSSPRVGPPHALPLYP-----
-----EKFSHEKIALGAED----NCNLSDRFHEHENVKSRKRR--YDNLENS--DSYIEK
KARRSLQNDPLEESKVKKHKKSKKKKKSKDKHRDRNS--RHQDSDLSVGYSDADLHRHKK
K--KKKKKRHSRKSEDFVKDSEQYLPKSASYETIDRFR--RTEGNFLLTS----------
--SLPLEGVGPFR--EKTKHLRMENR------------DKCHLSEFGQGK----------
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSCEAVSPEDMDTGSASWGA-VSSISDVSSHTLPLG
PVPGAVVYSNSSVPEKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRAVLNQQA
YVLFYIRSHDVKNGGESAHPAH-SPGQSSPRPGISQRVVNN-KQAAPGFIGPQLPSHVMK
-NTPHLNGTT--PVKDTPSSSVSSPNGNTS-VNRASPA-TASTSVQNWSVTRPSV--IPD
HPKKQKITISIHN-KLPARQGQAPLNNSLHGPCLEAPSKAAPSSTITNPSAIQSTSNVPT
TS--------------TSPSEA---------------CPKPMVNGKAKVGAS------VL
VPYGAESSEESDEE-SKGLAKEN----GVDM---------MAGTHSDRPEAAADEGAEAP
SHEL-----QEPILLNGANS--ADSD----------SQENSL-AFDSASCQVQPELHTEN
LFSKLNGLPGKVTPAPLQSVPEDRILE--TFKLTNQAKGPAGEE----SWTTTGGSSPKD
PVS-QPEPISDE-PSPLEIPEAVTSGSTQTPSTT-SPLEPTISC----------TKEDS-
SVVVSAEPVEGLPSV-PALCNSTG-TILG-DTPVPELCDPGD-LTANPSQPTEAVKGDTA
EKAQ-DSAMAEVVERLSPAPSVLTGDGCEQKLL-LYLSAEGS-EEAEDSSRSSAVSA---
---DTMP----PKPDRTTT--SSCEGAAEQA--AGDRGDGGHVGPK----AQEPSPAKEK
MSSLRKVDRGHYRSRRERSSSGEHVRDSRP------RPEDH--HHKKRHCYSRERP---K
QDRHPTNT-YCNGGQHL-GHGDRASP-ERRSLSRY--SHHHSRIR----------SGLEQ
-DWSRYHHLENEHAWVRERFYQDK-LRWDKCRYYHDRYT-P-LYTAR-DTREWRPLHGRE
HD------RLVQSGRPYKDSYWGRKGWELQ-SRGKERPHFNSPREAPSLAVPL-------
-----ERHLQEKAALSVQD---SSHSLPERFHEHKSVKSRKRR--YETLENN--DGRLEK
KVHKSLEKDTLEEPRVKKHKKSKKKKKSKDKHRDRE-SRHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEDFIKDVEMRLPKLSSYEAGGHFR--RTEGSFLLAD----------
--GLPVEDSGPFR--EKTKHLRMESRP-----------DRCRLSEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENPTKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IVSSHSPGQD--AEDEEATP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDKILE--TFRLSNKLKGSTDEM----SAPGAERGPPED
RDA-EPQPGSPA-AESLEEPDAAAGLSST-KKAPP-PPDPGTPA----------TKEGA-
WEAMAVAPEEPPPSAG-------Q-DIV-GDTAPPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSALAEAPEGLSPAPPARSEEPCEQPLL-VHPSGDHAR-DAQDRSQSLGAPE---
-AAEGPPA---PVLEMAPA--GHPEGDAEPS--PGERVEDAT-APK----APGPSPAKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------PEHHPGHGDRLSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYPDR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHNRGRRGCEPA-R-ERERHRPSSPRAGAPHALAPHT-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENGKSRKRR--HDSVENS--DSHVEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSELSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRVASLETVAQFR--RAQGGFPLSG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCRLFEYGQGD----------
-----------------------------------

MTVFGRA-----DSSDPSARQNQPGRSEAVSTGDVDAGSAGWSA-VSSLSDVSSHTLSLG
PVPGA-AYSDSALSDRSEPSPPKDQ---G-------DGIALPQKILFPSEKICLKWQQTH
-GVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 229)

GLQNLGNTCFANAALQCLTYTAPLANYMLSHEHSET--CHAEGFCMMCIMQDHIT
QALNNPGDVIKPMFVINEMQRIASHFQIGEQEDAHEFLQHTVDAMQEACLSGSNE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTTVDKT-----EPSDPSTCQNQPGSSEAVSPEDMDTGSASWGA-VSSLSDVSNHTLSLG
PGPGAVVYSNPSVPDKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQTHIT
QALSNPGDVIKPMFVISEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCNKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGELAHSTH-SPGQSSPRPGISQRVVNN-KQAAPGFIGPQMPSHVMK
-NTPHMNGTA--PLKDAPSSSMSSPNGTTS-INRASPV-TASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQAQLNNNLHSPSLEAPSKAVPSSTITNASSIQSTSNAPT
MAVS------KK--------VS---------------CSKPMVNGKAKLSSG------VL
VPYGAESSEESDEE-SKGLAKEN----GLGM---------MASAHCSGLEAEDEDSEATP
HEL------QEPIMLNGANS--AESD----------LRENGL-AFDVASCQVQPTLHTEN
LFSKLNGLPGKLIPAPLQSVPEDKVLE--TFKLTNQVNSPADGA----SWTATGESPPKT
PAA-EPQPCSAEV-GPLETPEAVASPSQTS--TVLSPLDPAINSTK----------D--A
SMVVATKPVEALSP--ATPCSTNG-DILG-DAQLQEPCAPGD-LGADRGQPAPAPEGTGT
EAEA-AQDPAEAAQRLSPAAQRLAGDGSEQKLF-LYLCTEGF-EEAPDSSRSSGASV---
---AAMP----PQPDRTT---SSSEEAAEQV--AGERGAGGPAGAL----AQEPSPAKEK
PTTLRKVDRGHYRSRRERSSSGEQARDSRR------GEDHHH-HHKKRRCQSRERP---K
-AERHPAA-HCNSS--HLGHGNRASP-ERRSLSRY--HHHS--RL----------RGPEQ
-DWSRPHHGDGDQAWGRERFYPDR-ERWDKCRYYHDRYA-P--YAAR-DSRDWRPPHSRE
LE---------HAPRPHKDCHWGRKGWEPA-RK--ERPHFHGPH-GPGLALPLDR-----
--------HLQEKALGSQD---SSYSLPERFHQHESARSRKRR--YES---S--DGRMQK
KVHRSQEKGPLEEPRAKKHKKSKKKKKSKDKHRERD-CRHQQDSDFSGTYSDADLHRHRK
K--KKKKKRHSRKSEDFMKNVELHLPKPSSYEASGHFR--RTEGAFLLAD----------
--GLPLEGSGLFW--EKTKHLRMESRP-----------DRCHLSEYGQGKGCM-ELQTHK
KIE--------------------------------

MTIVDKA----SESSDPSTYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGITPPQKVLFPSEKICLKWQQTH
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

RVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSAH-SPGQSSPRPVIGQRVVSS-KQAASGFIGPQPPPHVMK
-NPPHLNGTG--PLKETPSSSMSSPNGNSS-VNRAGPV-NASTSVQTWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PHLHGSPLESPSKPVPSSTVTNSSTIQSTSSAPT
TSVS------SKATKQMAPNES---------------SSKPVMNGKSKLNSS------VL
VPYGAESSEESDEE-AKGLGREN----GLAA---------AGSSHPSAQD--AEDDAASR
LEL------REPVTLNGANS--ADSD----------PKENGL-SFDGASCQVQPALHAEN
PFAKANGLPGKLMPAPLPPLPEDTVLE--TFKLSHKAKGSTDET----SATGTEGSPTED
PGR-GPEPGSPS-PDAQERPEAATGLSSKLKKAA--ARDPGAKP----------AKEEG-
SENVSAKPEESLPST-SP-------GTIA-DGHPAKPCDPGD-LTSEPSKAAQDVKGTSV
ESPR-DSVAMETTGRLSLSPSSHPAGDSEQGPS-VHSSRDKC-TDAEDLSQGAGAST---
---DEPPS---AQLDKVAE--SRSDGAPEQS--PSEQREEQKAGPK----APDRSPVKEK
ISSLRKVDRGHYRHRRDRSSSGERARDSRS------RTAEQ--HRR-RHSY---------
------------------------------------------------------------
---XR-HHPPEGEHWGREKYYPEK-TRWDRCRYYHDRYA-P--YAAR-ELRHWKPFHGDR
DC----DRAAQ--HRPYKDYYKGRKGCEPV-VKEKEGPHFGSPRGAPPHAPPLYP-----
-----DKYSHGKMALGAED----GCHLADRFHGHESIKPRKRR--YDSMEHS--DSYAEK
NAWRSLQREPLDEPKAKKHKKSKKKKKSKDKHRERDSSRHQQDSDLSAAYSDADLHRHKK
K--KKKKKRHSRKSEDFGKDSELHLPKAASSETVDHFR--RTDGGFPLTD----------
--GLPLEGVGPFR--EKTKYLRMESRN-----------DRCHLPECGQGKRRYLELKM--
-----------------------------------

MTIVDKT----SESSKPSASEKQPLSSVAPASGDMDSGSAGWGA-VSSSLEAPKHKITLG
PVPGAAVYSNSSVPDKSKASAQKDLS-IG-------DGIAAPQKVLFPADKISLKWQKMH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFLNSALQCLTYTPPLANYMLSHEHSKT--CHEQGFCMMCTMQSHIT
QALSNSGNVIKPMPVINDLRRIAKHFRFGNQEDAHEFLRYTVDAMQKACLNGSNKLDRHT
QATTFIHQIFGGYLRSRVKCMNCKGVSDTFDPYLDITLEIKSAQSINKALEQFVKPEQLD
GENAYKCSKCKKMVPASKRFTVHRASNVLTLSLKRFANFSGGKITKEVKYPEYLDIRPYM
SQPNGEPIIYALYAVLVHTGFSCHAGHYYCYIKASNGQWYQMNDSTVSNSDIRTVLNQQA
YVLFYIRSHDMKNGGEHIHSAH-TPGQSSPRPVINQRVVNN-KQTAPGFIGPQLPPHMIK
-TSNHLNGTG--SLKETASSSAIASNAT---LSRPSSA-PPATSIPNWTMNRPATATAPD
PSKKQKITISIHNNKLPGRQSVSH-----ASCTLDNLNKPAPSSTISNPSAVQSTSSAST
ALAA------NQVPKQTAPSEP---------------SSKLVVNGKSKLSPS------ML
VPYGAESSEDSDEE-LKGLVKENGHSKPFNGILTEKASTVLESSCSSFHN---PEKEVPP
HEP------PKNITVVFSIS--LNDS----------SKQNGQ-ICNDSTCQAKPVKSSEN
PFSKTNGLPGKGTPIALTPVPEDRIVD--SFRYNQLKPFSGD-I----SASGSEKPLEEG
GCS--------------EK--VPCPLTSDVQN-LLAPSDPEITSTTEDPCERV-------
PSQTGAVPLESLGQH-----GLPS-TPLRAKEDFPGESNVED--HAEKTRGPKEGKAAWE
KSAEVARGNADATEKGPQSPLLWADSECSSQKLVALNMADKCQETQDNVKMYEDASPTEN
SCT--------LRPN-VVG-----ESSKDDQGENSEQFKGN----TDRQELRSHSPFREK
VCTSRKTDKEHYRSKRKHSESEEEVEATAGAS-SRSQAEGH--HNKKRCSYSKERV---R
PQEHYRRE-HYNTNYY----RFPCSPDPGRNFGKY--PPYRSRSR----------GKTES
-ERSRHC---YERSWSRERYYQDVPRRWEGCRSSDYYYP-SHV--PR-YNQDKKFTLCER
DY----NKSSHVYNSPYKYDYHKNRW----------------------------------
----------------------------------THDQERKRK--CQSPEGS--QGTPEK
RPQKTVQSESLDEQRGRKHKKSKKKKKLKDKHRERD-HRHHQDSDPSASSSEAEVHRHKH
KKKKKKKKKRTKKSEDCSETLVPSLPKATSLETKNLKTWEATKSSFEACR---------K
HGRAHQDGDTAVC--QKTKSIEGCNRNGSSPSTDHNVDPDCPLEAIPPQLAGYL------
-----------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-ML------LKSGHSI-------------------CNFCR--TLLSYHCL--FFRLDR

PF00443 // ENSGT00890000139343_4_Domain_3 (239, 425)

HT
QATTFVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAVQSVNKALEQFVKPEQLD
GENAYKCSKCKKMVTASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELAHSTH-SPGQSSPRPVINQRVVNN-KQAAAGFIGPQLPSHIMK
-NPPHLNGTG--PLKDTPSSSMSSSNGNSN-VNMASPV-NASTSVQNWAVNRSSV--IPE
HPKKQKITISIHN-KLPGRQGPSQ--PNLHSNSVENPNKPAPSSTITNSSAIQSTSTTST
MSIS------SKVTKLTTPSEA---------------CSKPVMNGKSKLNSS------VL
VPYGAESSEESDEE-PKGLGKENGV----SA---------ISSSLSPSQG--AEDDEVSQ
HEL------QEPITLNGANN--VDSD----------PKENGL-PFDDADCQVQPALHSEN
PFSKANGLPGKLMPALLPSLPEDNILE--TFKLSNAVKGSTDET----SIPGAEKTPPEE
QDM-EVEEAGSPADDPEEKLETVESLGSKLKKVLSLP-DPSVKS----------TKEVV-
SENSSAKPDESLSGINILCN--TN-KNTLGDDQLSKLCDPGD-LTDDQSKPSQDVKGTLV
ESPQ-DTVPVETVEKLSPAPSAHSEDGRECQAL-AYLGRDRG-KDEEDLPSSMGVCA---
---EGLPP---PQPDKTTG--DPSEGDTEQS--HAERCDESKVGQK----VRDRSPIKEK
ISSLRKVDRGHYRNRRARSSSGEHAKESRS------KTEDH--YYRKRRSYVRER----S
RQDRYTTE-HCNGSQHHLNHGDRVSPGERHSLVRY--SYHHSRNR----------SGSDQ
-DWNRYHHAEGEHIWGREKYYPDK-MRWDKCRYYHDRYA-P--YTAR-ESREWKPFPGGR
EP----DRAGQRHGRLHKDYYRSRKDYEVA-AKEKVRHHLSSPRAGPPHSLPPYP-----
-----EKFSHDKIALGAED---NSCNLSDRFHEHENVKSRKRR--YDNVENN--DSHVEK
KAQRSLQKDPLEEPKVKKHKKSKKKKKSKDKHRDRN-SRHQQESDLSVVCSDADLHRHKK
K--KKKKKRHSRKSEDFFKDSELHLPKSADYETVDRFR--RSEGGFLLTD----------
--GLLPEGVGPFR--EKTKHLRMENRD-----------NRGHLFEYGQGN----------
-----------------------------------

------------------------------------------------------------
---------------------------LG-------DGIAPPQKVLFPSDKICLKWQQTH
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

RVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNXXXXXX
XXXXXXXXXXXXXXXXXXKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCNKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKEVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXX
XNPPHLNGTG--PLKEMPSSSLSSPNGNPS-VSRAGPV-NASTSVQNWPGNRASV--VPE
HPKKQKITISIHN-KLPTRQGQPQ--PSLHNSSLETPSKPTPSSTVTTSSPAQSTSHASP
VSAS------SKGPAQLSPGEP---------------CPQPVVNGKAKLNAS------VL
VSYGAESSEESDEE-SKGLSKEN----GLGP---------AESARP---FCDAEDDATTQ
HGL------PGPLLLNGASS--ADSN----------SKENDL-PFDGAGCLTLPAPLSDN
PFS-ANGLSNKXXXXXXXXXXXXXXXX--XXXXXXXX----XXXXXXXXAAGVEKSPTEV
PDGDDAEVASSSPLGPTETPEAAPCLGSKSQKL---PPEPSFQSTKVATCD---------
--------AEPVPSTE---------SP-LEDGLHTQPCDPGDVPV----DESQDTSGTSL
ESSQ-GPALADTAAEGTPAPSLSLDHEREHKLV-VFISREKCR-DLEDLASSLGPPE---
-----LPS---LRLDPLPE--HPSEGAPAPG--TGVRGDENQAGQR----AAARSPAKEK
MGSLRKVDRGHYRNHRDRSSSGEYAREGRS------KTEERA-PKLQRLSHTHER----P
RQDRQKAE-HCGGSSTQL--------NERHSLGRH--GHPPPRLR----------SGSEQ
-EWGRYHHSESEHCWGRDKSYPEK-ARWEKCRYYHDRHS-L--YDGR----ERKAFRSER
EHXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XX----------XXXXXXXXXXX
XXXXXXXXYPEKGPLGTEE---LGCPLPVRFQEH--SKSRKRR--YGSVELG--GSHAER
RDRRSLPKEPLEEPKVKKHRKSKKKKKSKDKHRDRDS-----------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSSYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLALG
PVPGAVVYSSSSVPDKSKPSPQKDQA-VG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDMKNGGELTHSTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPGSSMSSPNGNSS-VNRASPV-HASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQGQPQ--PNLHSNSLENPTKPVPSSTITNS-AVQSTSNASM
MSVS------SKVTKPIPCSDS---------------CPQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPSQD--AEDEETAP
HEL------QEPMILNGANSADSDSD----------LKENGL-PPDGASCQSQPALHSEN
PFAKANGLPGKLIPAPLPSLPEDKILE--TFKLSNKVKGSTDET----SAPGAERGPSED
CIA-EPQPCSPA-AESLEEPDLAASLSS--TKVPP-PPDPGTPA----------TKEGT-
WEAMSAAPEEPPPSAG-------Q-DINTGDTTPPDLCDPGS-LIGDPSPQSQD-TGMIV
ESPR-DLVSAEVQEGLSPAPPMGSEESYEQPLL-VHPSRDHTR-DAQDPPQSSGAPE---
-ASEGLPA---PALEAAPP--SHPVGDPEPS--PGEKGEDAAVGPK----VPGPSPAKEK
IGNLRKVDRGHYRSRRERSSSGEPARESRS------KTEGQGHRHRRHRT----CTRERD
RQDHHA-------SEHHPGHGDRLSPSERRSLGRY--GHHHSRHR----------SGAEL
-DWGRHHYAEGEHSWGREKFYPNR-PRWDRCRYYHDRYA-L--YA----ARDWKPFHSGR
EHERAG-----LHERPHKDHYQGRRGCEPA-R-ERERHRPGSPRAGAPHTLVPHP-----
-----DRFSHDRTALVAED---NNCNLSDRFHEHESGKSRKRR--YDSLENS--DSHVEK
KSQRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRGRDS-RHQQDSDLSAACSDTDLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAHFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLRMESRE-----------DRCHLFEYGQGD----------
-----------------------------------

MTIVNKPKSSKSK----KSSSRRSDKSMKPRTKKMTSRTASLGR-VPPTEDPN--KVSVD
KGPGGHIYCRSS--QKSKPFAQRDLV-VN-------DGIAPPQRILFPPEKICMDWQQTQ
-SVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

VGLQNLGNTCFLNSTLQCLTYTPPLANYMLSLEHTKS--CHVEGFCMMCTMESHIN
QVLCCSNNAIKPTSVINGLKRIGKHFHFGSQEDAHEFLCFTVDALQKACLNGSTKLDRSS
QATTLIYQIFGGYLRSRVKCLNCKAVSDTYEPFLDVTLDIKAVTSVTRALEQFVKPEQLD
GENSYKCSKCKKMVPASKRYTIHRSSNVLTISLKRFANFTGGKINKDVKYPEYLDLRAYM
SQSIGEPLIYALYAVLVHSGFNCNAGHYLCFIKAGNGLWYRMNDASVELSDIKTVLNQQA
YVLFYIR-RYDLTLGERA---FYLPTPSYPRSFLGQRGANS-K--QAAFMGPRLPPHMIK
-SSSRLNGNG--PLKEDPSAVGV-------AVKRPSSA-PPTACVQNWAISRPSM---TD
PSKTQKITISIHN-KLPTRQAVPQAECPSSAREEEDL-KPLPSATITNSSAAEPTSNLST
VSVA------TNVSKQEVPDEI---------------FVEPAVNGNPKLCSD------NM
VPFGAEPSGKSEE--SKGLFKRHCNIISSN------------NSHSSCQN---AE-ERSQ
HEL------PKIDSLNGAIS--LDNE----------YKENGL-KLDDSTCQVQPVKPSEI
FFAKANGVL-EAMPKPLSPDPQG-ILE--SLTYSQLN-SLSEEK----SVSGPQKSSDND
GVTDTV-VME-ALFAYEESRKVPSKFSCEVEKLFT-Q----------SDSETIFTKEEV-
AESIITKADNAHLNI-N--------------GEFLGQCESEDIRDKDKLRRSKEPEFISK
ENPLYIKGSPESKEKLGQISSIKPDIECSSKKLASLDITDKCQDTKDISNNYVEVPPVND
SSI--------TKLDKVLESQFSRA----DEGPSNQTCED----D-----GKHMKKNKKK
IHDSKRTDKEHYRRKRENSDTEEKERQTRN------KSDDH--SHRRRSSHSVET----N
KQSRHKQE-YCSESKYRSSHSERNTLSNGRSSGKY--SRYRSRSR----------ERTDP
-DRNRYYYSKGDRPWIRERYYQDEPRRWEKCRYYNDYYS-SH---GTRDGRERRSSHCDK
DYDKSS---QAY-SRSHKDYHCKSRWAHSTLSREEDVHHFSSHRANFHHCSV--------
PQQHSEKYSHERHTLPPVS-AHSNFEDSSRENEKEKLRNGKRK--YSHQEES--GSDIEK
KC------RKTDDQRIKKYKKVKKKKKSKDKHREKDY--KLYDLDCSVLHFDNDNRKHKK
K---KKKKKHDRKLKDLLE-----------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQNH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-INRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHNNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGRD--AEDEEAAP
HEL------QEPVTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDEILE--TFKLSNKLKGSTDEM----SAPGAERGPPED
GDP-EPQPGSPA-AESLEEPDAAASLSST-KKAPS-PPDPGTPT----------TKEGA-
WEALAAAPEELPPGAG-------Q-DIA-GE----------H-LTGDASPLSQDAKGMIA
EGPR-DSAMAEAPEELSPALPARSEEPCEQPLL-VHPSGDHAW-DGQDLPQSSGAPE---
-AAEGPLA---PVPEAAPA--GHPEGDAEPS--PGERGEDAA-APK----APGPSPVKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRGT----CPRERD
RQDRHA-------AEHHPGHGDRPSPGERGSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYADR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPRKDHSRGRRGSEPA-R-ERERHRLGSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENVKSRKRR--HDSVENS--DSHVEK
KARRSELKDPLEEPKVKKHKKSKKKKKSKDKHRERDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCHLFEYGQGKRRYLELRR--
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSCEAVSPEDMDTGSASWGA-VSSISDVSSHTLPLG
PVPGAVVYSNSSVPEKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRAVLNQQA
YVLFYIRSHDVKNGGESAHPAH-SPGQSSPRPGVSQRVVNN-KQVAPGFIGPQLPSHVMK
-NTPHLNGTT--PVKDTPSSSVSSPNGNTS-VNRASPA-TASTSVQNWSVTRPSV--IPD
HPKKQKITISIHN-KLPARQGQAPLNNSLHGPCLEAPSKAAPSSTITNPSAIQSTSNVPT
TS--------------TSPSEA---------------CPKPMVNGKAKVGAS------VL
VPYGAESSEESDEE-SKGLAKEN----GVDM---------MAGTHSDRPEAAADDGAEAS
SHEL-----QEPVLLNGANS--ADSD----------SQENSL-AFDSASCQVQPELHTEN
LFSKLNGLPGKVTPAPLQSVPEDRILE--TFKLTNQAKGPAGEE----SWTTTGGSSPKD
PVS-QLEPISDE-PSPLEIPEAVTNGSTQTPSTT-SPLEPTISC----------TKEDS-
SVVVSAEPVEGLPSV-PALCNSTG-TILG-DTPVPELCDPGD-LTANPSQPTEAVKGDTA
EKAQ-DSAMAEVVERLSPAPSVLTGDGCEQKLL-LYLSAEGS-EETEDSSRSSAVSA---
---DTMP----PKPDRTTT--SSCEGAAEQA--AGDRGDGGHVGPK----AQEPSPAKEK
MSSLRKVDRGHYRSRRERSSSGEHVRDSRP------RPEDH--HHKKRHCYSRERP---K
QDRHPTNS-YCNGGQHL-GHGDRASP-ERRSLSRY--SHHHSRIR----------SGLEQ
-DWSRYHHLENEHAWVRERFYQDK-LRWDKCRYYHDRYT-P-LYTAR-DAREWRPLHGRE
HD------RLVQSGRPYKDSYWGRKGWELQ-SRGKERPHFNSPREAPSLAVPL-------
-----ERHLQEKAALSVQD---SSHSLPERFHEHKSVKSRKRR--YETLENN--DGRLEK
KVHKSLEKDTLEEPRVKKHKKSKKKKKSKDKHRDRE-SRHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEDFIKDVEMRLPKLSSYEAGGHFR--RTEGSFLLAD----------
--GLPVEDSGPFR--EKTKHLRMESRP-----------DRCRLSEYGQGD----------
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSSEAVSPEDMDTGSASWGA-VSSISDVSNHTLSLG
PVPGAVVYSNSSVPDKSKPSPPKDQV-LG-------DGIAPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCIMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGEPAHPTH-SPGQSSPRPGISQRVVNN-KQAAPGFIGPQLPSHVMK
-NTPHLNGTT--PVKDTPSSSMSSPNGNTS-VNRASPVVNASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQAQLNNNLHGPSLEAPSKAAPSSTITNPSAIQSTSNAPM
TSVS------NKVAKSVSPSES---------------CSKPMVNGKAKVSSS------VL
VPYGAESSEESDEE-SKGLAKEN----GVDM---------MASTPCARPEAEDADGEASP
QEL------QESVTLNGANS--ADSD----------LRENGV-AFDSASCQVQPDLHTEN
LFSKLNGLPGKVTPAPLQTVPEDRILE--TFKLTNQAKGPSGEE----SWTTTGESPPKD
PVS-QLEPISDE-TGPLETPEAVTNGNMKTPTTMS-PLEPTINC----------TKEDS-
SIVVPANPVEALPSV-TALCDTTG-TTLG-DAPLPELCDPDD-LITNQSQPTQVVKEEIA
ENPQQDSTLAEAVERLSPAPSVLTGDGCEQKLF-LYLSTEGS-EEAEDSSRSSGISA---
---DPMP----PQPDRTT---SSCEGAAEQV--TGERGDGSKVVPK----VQEPSPAKEK
VSSLRKVDRGHYRSRRERSSSGEPARDGRA------RTEDR--HRKKRRCYSRERG---K
QERHPANT-YCNGGQHL-GHGDRASP-ERHSASRY--SHHHSRVR----------NGPEQ
-DWSRYHHLENEHAWVRERFYPDK-MRWDKCRYYHDRYV-P--YTA----REWRPLRARE
HE------RSAQLGRPHKDSYWGRKSWELQ-PRGKERPHFHNPREAPGLALTL-------
-----ERHPQEKAVLDVQE---STHSLPERFHEHQSVKPRKRR--YETLEN---DSRLEK
KAHKSLEKDTVEEPRTKKHKKSKKKKKSKDKHRDRD-GRHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEALMKDVEMHLPKPSNYEAVGHFR--RTEGTFLLAD----------
--GLALEDSSSFR--EKTKHLRVESRP-----------DRCYLSEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSTYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPEKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSAH-SPGQSSPRPVIGQRVVNS-KQTASGFIGPQLPSHMMT
-NSPHLNGTG--PPKETPSSPMSGPSGNSS-VSR--TV-NASPSVQNWSVSRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--SSLHSNSLEHPNKPAPSSTITASCAIQSTSSAPT
PPAS------SKVPKQTAPREA---------------CSRPVMNGRPRLSAG------VL
VPYGAESSEESDEE-AKGLGQEN----GRGL---------TESVCSPAPD--AEDGDASP
HEL------REPVALNGATG--PDSD----------PMENGL-PSDGAPCPGQPALHSEH
PFPKANGLPGKLMPAPLPPLPEDKILE--TFKLSSKAKGSAEET----RTPGSEERPLEH
LEA-ELEAGRSPPGDARDNLEPVSNLSSKLKKASP-PSDPSIKP----------TKEEV-
SEHVSAEPEEAVPSV-STFCNPNK-DALG-DDQLPAPCDPGN-LTDDQSKPSPDVGGTLP
EQPP-DPVAAEATGRLSPVPSVPSEGDREPEPL-GHSGRDRG-SEAEGPAKSTGVST---
---DEVPS---PQLDMITE--NRPEGPPERS--SSERGEDSKAGHK----APEPCPVQEK
VSSLRKVDRGHYRSRRDRSSSGERARESRS------RTEVQ--HRRKRPHREHE-R---L
RPERPRLE-PCALAPQPPCP---------SSLARS--GHHHSRSR----------GAPDQ
-EWGRYHHAEGEHAWAREKYYPDR-LRWERCRYHHDRSP-L--YPGR-EPRDWRPFHAER
EY----ERAGPYGGRPYKDHYRGRKGYELA-AKERDRHRFSSPRAGVAHAPPPHPA----
-----AKYAHDRLGFGAED---GSCDLATRFHEHDNVKSRKRR--YDSLEN---ESHVEK
KAWRSLQKDPVEEPKVKKHKKSKKKKKSKDKHRDRD-SRHQQDSDLSVAHSDADLHRHKK
K--KKKKKRHSRRSEDFGRDSEPRLPKAASCETVDHFR--RAEGAFPLAD----------
--GLPLEGAAPFC--EKTKHFRMESRE-----------VRCRLSECGQGD----------
-----------------------------------

MTVIGRA-----DSSDPSARQNQPGRSEAVSTGDVDAGSAGWSA-VSSLSDVSSHTLSLG
PVPGA-AYSDSAVSDRSEPSPPKDQ---G-------DSIALPQKVLFPSEKICLKWQQTH
-GVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 229)

GLQNLGNTCFANAALQCLTYTAPLANYMLSHEHSKI--CHAEGFCMMCIMQDHIT
EALNNPGDVIKPMFVINEMH----HFQIGEQEDAHEFLQHTVDAMQEACLSGSNE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENPTKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IVSSHSPGQD--AEDEEATP
HEL------QEPMTLNGANSADSDSD----------PKENGL-APDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLLSLPEDKILE--TFRLSNKLKGSTDEM----SAPGAERGPPED
RDA-EPQPGSPA-AESLEEPDAAAGLSST-KKAPP-PRDPGTPA----------TKEGA-
WEAMAVAPEEPPPSAG-------E-DIV-GDTAPPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSALAEAPEGLSPAPPARSEEPCEQPLL-VHPSGDHAR-DAQDPSQSLGAPE---
-AAERPPA---PVLDMAPA--GHPEGDAEPS--PGERVEDAA-APK----APGPSPAKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------PEHHPGHGDRLSPGERRSLGRC--SHHHSRHR----------SGVEL
-DWVRHHYTEGERGWGREKFYPDR-PRWDRCRYYHDRYA-L--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHNRGRRGCEPA-R-ERERHRPSSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENGKSRKRR--HDSVENS--DSHVEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRVTSLETVAQFR--RAQGGFPLSG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCRLFEYGQGD----------
-----------------------------------

MTVLGRA-----DSSDPSARQNQPRRSEAVSIGDVDTGSASWRA-VSSLSDVFSHTLSLG
PMPSA-GYSDSAVSDRSEPSPPKDP---G-------DGIALPQKILFPSEKICLKWQQTH
-GVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 229)

GLQNLGNTCFANAALQCLTYTAPLANYMLSHEHSET--CHAEGFCMMCIMQDHIT
QALNNPGDVIKPMFVINEMQRIASHFQIGEQEDAHEFLQHTVDAMQEACLSGSNE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGITPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHSNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGRD--AEDEEAAP
HEL------QEPMTLNGANSADSDSD----------PKENGL-PPDGASCQGQPALHSEN
PFAKANGIPGKLMPAPLPSLPEDKILE--TFKFSNKLKGSTDEM----SAPGAERGPPED
GDP-EPQPGSPA-AESLEEPDAAASLSST-KKAPP-PPDPGTPT----------TKEGA-
WEALAAAPEEPPPGAG-------Q-DIA-GDTAPPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSATAEAPEGLSPAPPARSEEPCEQPLL-VHPSGDHAR-DAQDLPQSSGAPE---
-ATEGPPA---PVLEAAPA--GHLEGDAEPS--PGERGEDAA-APK----APGPSPVREK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRRT----CPRERD
RQDRHA-------AEHHPGHGNRPSPGERRSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYADR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPHKDHSRGRRGCEPA-R-ERERHRPGSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENVKSRKRR--HDSVENS--DSHVEK
KARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLRMESRD-----------DRCHLFEYGQGD----------
-----------------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLALG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

RVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSPH-SPGQSSPRPVISQRVVSSKQATAGXXXXXX-XXXXXX
-XXXXXXXXX--XXKETPSSSLSSPNGNSS-VNRAAPV-GAPTSVPNWSVSRPSV--LPE
HPKKQKITISIHN-KLPVRPGPPQ--PGLLSSPLETPAKPAPSSTVTNPSAIQSTSSTAA
PAAS------SKATKPPAPSEP---------------CAAPVVNGKARLHAS------VL
VPYGAESSEESDEE-AKGLGREN----GLGV---------TQGTAG--------GETAPH
ELL------REPAALNGADG--ADGE----------PTAHGP-SLDGATGQGQPPLHTEN
PFAKANGLPGKLMPAPLPPLPEDKILE--TFKLSNKAKGSAEES----XXXXXXXXXXXX
XXX-XXXXXXXXXX--XXXXXXX-------------------------------------
-------------XX-XXX---------X-XXXXXPTGDPGS-TAEEQGRAFPDTA----
SPQR-PPAPGSTAGELSPAPSARPEVDGTHELL-VHISRDVGAAAEG-------------
-----LPA---VPADKA--A-EGPTEGARQS--PGE-LVRKAGGHR----VPGPSPGKEK
ISSLRKVDRGHYRNRRDASSSGERTRESRS------KTEDH--YHKKT--CLRER----A
KQECHRRE-HCSGS-----HGDRGSPGERRSLGRY--GHQG-------------------
--VEPHHHSESEHAWGREKYYPEQ-ARWGKCRHYHSRSA-L--YA-----RDWKAFPGAR
-------------DHPAYDYYKGRKAYEKE------------RHHGPAHSLPLYP-----
-----EKYSHEKTALGAE----GGCDLSGRFRGPENTKPRKRR--HDSVENV--DGHGGK
PAWRSAPKGPLEEPKAKKHKKSKKKKKSKDKHRARD-SRHPPDSDLSGAYSDADLHRHKK
K--KKKKKRHSRRSGDFAQSSGLHPPQASGPKPTHLFR--RTEDGLPPAD----------
--GLAL---------EKTKHFRLESRA-----------DRCPLSECGQ------------
-----------------------------------

MTIVDKA----SESSDASTCQNQPGSSEAVSPGDMDAGSAGWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVITQRVVNN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKETPSSSMSSANGNSS-VSRAGPV-NASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRPGQSQ--PNLHSGSLENPHKPVPSSPITASPAVQSTSSAPA
APAS------SKVAKQMTPAES---------------CATPVMNGKSKLNSS------VL
VPYGAESSEESDEE-AKGLSKEN----GLGT---------TESSPSSAQG--AEDDEASQ
HEL------LEPAALNGANS--TDGD----------LKENGL-SFDGASCQVQPALHSEN
PFSKANGLPGKLMPAPLPPLPEDKILE--TFKLSNKTKGSADGT----SPTRTEESPAES
PEA-APEAGSPA-PDARDKLQTLTSLSSKLKKALL-LSEPGSKP----------AKDDV-
AESVSAEPAEPLPST-AVLSPLG--------TISSPLCEPAD-LTNDPSRPSQAAKGALL
ESPR-DSAAMETVGRLSPSPSARAEGDGEHELS-VCSGCDKC-TAVEDPSKSTGASA---
---EESPS---PQLDTITE--GPPEGVPEHS--NSERGEENKVAQK----VQDHSPVKEK
ISTLRKVDRGHYRNRRDRSSSGERARESRS------KTEDR--YHKKRHSYVRER----A
KQERYRPE-HCNGSQHQPCHGERGSPSEHRSLGRY--GHHHSRNR----------GGSDQ
-EWSRYHHSESEHSWGREKYYPEK-MRWDKCRYYHDRYA-P--YAAR-EVWEWKPFHGDR
EY----DKAGQYASRPHKDYLKSRKGYELL-AKEKGRHHFSSPRAGPSHVLPLYP-----
-----EKYAQEKVALVAED---NTYHLADRFHEHETVKARKRR--YDSLENA--DSHIGK
KAWRSLPRDPLEEPKVKKHKKSKKKKKSKDKHRDRD-SRHQQDSELSGAHSDADLHRHRK
K--KKKRKRHSRKCEDALRDSGLRLAKAAACETVARFR--RAAGGFPLAE----------
--GLPLEGAGPFR--ENTKAFRVESRA-----------DRCRLSECGQGKRRCSELRT--
-----------------------------------

MTIVDKA----SESSDPSTYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSTVPEKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGDLTHSAH-SPGQSSPRPVLSQRVVSS-KQAASGFIGPQLPSHMIK
-NPPHLNGTGPGPLKETPSSSMSGPHGSAA-ANRAAPV-TASTPVPNWSVGRPSV--LPD
HPKKQKITISIHN-KLPVRQGPPQ--PDPHGGSPEGPAKPAPAATATAPSALQSTSRAAP
PPAA------GRAAKQLGPPEA---------------CSKPVMNGKSRLSSS------LL
VPYGAESSEESDEE-AKGLGKEN----GLGP---------AESARSPAPPD-ATAAEAPP
HELL-----ELPVALNGAPS--TDSD----------PKENGL-PSDGAGCPVQPALHPEN
PFSKANGLPAKLMPAPLPPLPEDRVLE--TFKLSTRAQGSADET----SSPGAEESPAEE
PAA-ELAAGSPA-PDAPENPETVASLSSTSKKASP-PSEPSINS----------TKE-A-
SENSAAKPEAPLPSSSSSLCTVSK-SPGG-DDARAQLADPASSSTHGPSKPSRDAEGLVT
ERPP-DSAAAEAAGRLSPSPSERSEDPREPELS-ALSRE-GG-AAAEAP-ASAGLPA---
---GEAPPPPPQPSDPRAE--RLAETGPEQS--GGDRAAESAASPKAQAPSPVPAPVPEK
ISSLRKVDRGHYRSRRDRSSSGERARGSRS------RTEEQ--HRRKRPR-----P---E
RPERPRPD-PCGPAPHHPAHG-----GERLSLARY--GHHHSRSR----------GGSEQ
-EWGRYHHAESEHAWAREKYYPDR-TRWAKCRHHHDRYA-P--YPAR-ELRDWKPFHADR
EY----ERAGPYGSRPYKDHYRSRKGYELA-AKDKERHRFPGPRAGPSHALPPPPPPHPH
PHPHPERFGPEKAALGAED---SGCHLAGRFHEHENVKSRKRR--YESLENA--DGHVEK
KAWRSFQKGPLEEPKVKKHKKSKKKKKSKDKHRDRD-SRHQPDSDLSGAHSEADLHRHKK
K--KKKKKRHSRKSADFVRAADAPLPKAASCQTVDRFR--RAAGAFPLPD----------
--GLPLEGAGPFR--EKTKHLRMESRA-----------DRCHLSECGQGD----------
-----------------------------------

MTIVDKA----SESSDPPAYQNQPGSSEAASPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSTH-SPGQSSPRPVISQRVVGNKQA-ASGFMGPQLPSHVIK
-NPPHLNGTG--PLKEAPSSSMSSPSGNSS-VSRAGSV-NASTSVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PSLHGPSLDTPSKPVPSSTVTS-SAMQSTSSASM
TAVS------SKVTKQMTPSES---------------CSKPVMNGKSKLRSS------VL
VPYGAESSEESDEE-AKGLGKEN----GLGT---------IESSNSSVQD--AEDDEASP
LEL------REPVALNGADS--PDSD----------LKENGL-PCDGARCPVQPALHSEN
PFSKANGLPGKSMPAPLPPLPEDNILE--TFKLGSKVKGATEET----SSPGTEEGPAEG
PGA-ELEPGSPSPD-SREKPETLTSLSSKLKKASP-PSDPSIQS----------TKEEV-
SENIAAKPEEFSPGA-DDLCGSTR-NGAG-DDPLPKPCGPGD-LTDDQSRPAQAASGTRT
DSPR-ASAAVEAAQGSSPSPPARSEGACEHEPF-CVSGDKRADTDTEGPWKGAGAAA---
-AAADLPS---PQVDTGT-E-RRSEGGPEQS--HGEKREENKVGQK----VPDRSPVKEK
IGILRRVDRGHYRNRRDRSSSGERARESRS------KTEDR--YHRKRRSYTRER----P
RQDRYRTE-HCGGSQHHPCHGERASPGEPRSLARY--GHHHPRSR----------GGSEQ
-EWGRYRHSEGEHPWAREKYYPEK-LRWDKCRYYHDRYA-L--YAA----REWRPFHERP
YD----KA--AAPGRPYRDCYRSRKGCEAA-AKGKGRHRFS-PRAGPPPAPLPYP-----
-----EKHPHEKLAPGAED---DPCDLAGRFHDHENVKSRKRR--YDSLENG--DGRGEK
RAWRGAQKEPLEEPKAKKHKKSKKKKKSKDKHRDRD-SRHQQDSDLSVACSDADLHRHKK
K--KKKKKRHSRKSEDFVKDSEPHLPKAASHETVDRFR--RTDGAFPLTD----------
--GPPLEGVGPFC--EKRKHLRMGSRD-----------DRCPLSECGQGD----------
-----------------------------------

MTFVDRA-----DSSDSSDHRNQRSHCEAASTADLGAGSADQSAESSSLSDVSIHTLSLG
PVLGA-VYSESIVAGKSELSPPKDQGSYC-------DGIPPPQKILFPPEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFVNAALQCLTYTPPLANYMLSREHTKT--CHAGGFCVMCIMQAHII
QALSHPGDAIKPIAVISELQGIASHFRFGNQEDAHEFLQYTLDAMQKACLQGSYELDRHT
QATTLIYQIFGGYLRSRVKCLNCRGVSDTFDLYLDVTLEIQDVRSVNEALAQFVKPEQLE
GENCYKCSKCNSMVPASKSLSIHRPSNVLTLTLKGFSNCTGSKIAKIVKYPEHLNIRAYM
SQPSGEAMQYSLYAVLVHTGSKCCVGHYFSYVKASNGLWYQMNDFMVSPSDISSVLSQQA
YILFYIRTYDVKHGGEVTAHFPCHPCQFSSHPDTHQCTSTK-EQAAPGFNGPQLPSHMTR
-NLPYWNRIR--APIDTSGSSTWSPGGNPK-VNRPRPV-QASTSVPNRIQLFPH------
--------------------------------------------SMLSSIQFLKTSQCTD
IAVTQLRNKRKGIWSEAVMNQSYRTQCIS-GQIPEHLQVHPVIIQHEHCIQSCHRHHWAV
SHFGKASATSHCDH--------------FSF---------YTILYFLGRV--ICEDMSGN
SHLHGTVS-TPD----GPQD--PMLGIEFVCTHLSEAMHALWPSTCALICSLKN------
PLLHSG------LLPCPRGC-GSDLL-SGDYLTSELPRERREAG----NVPGMEQSLFGD
LTA-ELEAVSVS-AGSHDEVDPIASLCEMFKKLLL-TPEISLKS----------MRD-VM
SETSSAITDVSLPFV-KKLCNKNQ-TSTG-ADPVYEPCDAGK-VTQDCSK----VKGLLP
ESLR-HSGLVGTVEQLSLAPFTQSEGRREPGPL-VSLRGEQCG-DTGAQTQNTGECA---
---NALPS---TQPQSTPG--THPEGDPV--HSHVKGCSQVQVVQK----IPDHRP--QK
ISSRTRCDHEGYHNHHDCSSTWED-------G--------S--CDRKWLCYARKH----S
KPECHAVQ-HRSANQHPLCCGDRVTPGEPCVLSRY--SSHHSQTW----------GGAEQ
-DWSPYRPSGREHRRLPEKSDPKK-MWWDQCRNL-NRYT-P--YEGR-------------
---------QRSVKRSHKDSSQARKGQELP-ALLWEWTGFHSPHTGASPPFPLHP-----
-----ECYPQEKAAFGADH---SGRSLSHGICGRETMRSGKRR--YQSAESICNGGSTPK
KACRSLPRD-PEEPNK-----------SKAKHHEQE-HRCLLDTDLPVVQSDTQPCRYQK
----------KRHSENFGTEPGLHSPKTTSCETVDDVW--RPQGSSLLAD----------
--GLPVEGFGLFQ--MEKKPLKLDSRT-----------DRYQ---YGQGKKRFVELRR--
-----------------------------------

MTIVDKT-----EPSDPSTCQNQPGSSEAVSPEDMDTGSASWGA-VSSISDVSNHTLSLG
PVPGAVVYSNSSVPDKSKPSPPKDQV-LG-------DGITPPQKVLFPSEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCIMQTHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQA
YVLFYIRSHDVKNGGEPAHPTH-SPGQSSPRPGISQRVVNN-KQAAPGFIGPQLPSHVLK
-TTPHLNGTT--PVKDTPSSSMSSPNGNTS-VNRASPV-NASTSVQNWSVSRPSV--VPE
HPKKQKITISIHN-KLPVRQGQAQLNNNLHGPSLEAPSKATPSSTITNPSTVQSTSNASM
TSV------------SISPSEP---------------CSKPMVNGKAKVSSS------VL
VPYGAESSEESDEE-SKGLAQEN----GVDM---------MASPPCARPEAKDEDSEASP
HEL------QESVTLNGANS--AGSD----------LRENGL-AFDSASCQVQPDIHTEN
LFYKLNGLPGKVTPAPLQSVPEDKVLE--TFKLTNQAKGPLGEE----SWTTTGESPPKD
PVP-QLEPSTDENG-SLETPEAVSNGS-------METQEPTINC----------TKEDY-
STVVSDNPVEVLPSI-TAPCNTTG-TTLG-DTPLPELCDPDD-LTTNPSQPPQAVKGEIA
ENPQ-DSTLAEAVERLSPAPSVLTGKGCEQKLF-LYLSTEGS-KEAEDSSRSLGVSA---
---DTIPP---PQPDWTT---SSCEGAAEQV--PGERGDGNKVGPK------EPSPAKAQ
VSSLRKVGRGHHRSRRERSFSGEHGRDCRA------RTEDH--HHKKRHCYSRERP---K
QERHSINT-YCNGGQHL-GHGDRDSP-EHRSLSRY--SHHHSRVR----------NGPEQ
-DWSRYHHLENEHAWVRERFYPDK-MRWDKCRYYHDRYT-P--YTA----REWRPLRSRE
HE------RTAQLGRPHKDSYWGRKGWEPQ-PRGKERPHFHSSREASGLSLSI-------
-----ERHPQEKAMLAVQD---SNHSFPDRFHEHESVKSRKRR--YETTEN---DSRLEK
KAHKNLEKDALEEPRAKKHKKSKKKKKSKDKHRDRD-ARHQQESDFSGAYSDADLHRHRK
K--KKKKKRHSRKSEDFVKDVEMHLSKPLSYEAVGHFR--RTEGTFLLAD----------
--GLPLEDSGSFR--EKSKHLRMESRP-----------DRCHLSEYGQGKKTGN------
-----------------------------------

MTVFGRA-----DSSDPSARQNQPRRSEAVSIGDMDTGSASWRA-VSSLSDVSSHTLSLG
PVPGA-AYSDSAVSDRSEPSPPKDP---G-------DGIALPQKILFPSEKICLKWQQTH
-GVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 229)

GLQNLGNTCFANAALQCLTYTAPLANYMLSHEHSET--CHAEGFCMMCIMQDHIT
QALNNPGDVIKPMFVINEMQRIASHFQIGEQEDAHEFLQHTVDAMQEACLSGSNE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKA-----EPSDPSAYQNPPGSSEAVSPGDMDAGSASWGA-VSSLNDVANHTLPLG
PVPGAVVYSNSSVADKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEAIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELPHSTH-SPGQSSPRPVISQRVVSNKQA-TPGFIGPQLPAHGMK
-NPPHLNGTG--PLKDTPSSSMSSPNGNST-VNRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQAYLE--CTCSVRSR--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVNKPKSSKSK----KSSSRRSGKSKKPSTKTMKSRTANWGR-VPPAKNRN--QVSVN
QGRGGAIYCRSS--EKPRPFSVKDLV-IN-------DGIAPPQMILFPPEKICMDWQQTQ
N

PF00443 // ENSGT00890000139343_4_Domain_3 (122, 425)

GVGVGLCNLGNTCFINSILQCLTYTPPLANYMLSLEHTQS--CDYPGFCMMCTMETHIN
RVLCCAHDAIKPVVIVHELKRIGKHFRYGAQEDAHEFLRFTVDAMQEVCLQGCTILDRSS
QATTIIHQIFGGFLRSRVKCLNCKGVSDTYEPFLDIPLDIKEVSSVTKALEQFVTPEQLD
GENCYKCNKCMKMVPASKRFTIHRSSNILTVSLKRFADFTGVKDTKEVQYPEYFDLRAYM
SQSVGEPLIYALYGVLVHSGVSSHTGHYYCFIKAADGLWYQMNDSTVVRSNIKTVLAQQA
YLLFYIR-RYDLTLGERT---FYLPAPPYPCSLVGQRENNR-R--QAGFMGPRLPPHMIK
-NSSRLNGKI--PLKEDPNSVDV-------SLKRPSSA-PPIACAENWAMVRPSI---TN
PSINQKLTIGIHN-KLPARETASEPDCLRALEEEEIMS--IPSSTVTN-PAAESTSNTPT
MLAA------SDIFEQEALDDI---------------LIEPVVNGIPELSSD------NI
VFYGTEFSGKSEEDSSEGLFTRND-----------NVC-TLQDSYSSCQN---AEEERSQ
HEL------PKNDSLNGANS--LDNE----------PKENGL-KLDDSSCQVPSDKPSKM
LFSKTNGVL-KTMPITLYPVSREMILN--SFTYGQLN-SLSEEI----SVPGPQKSSENN
YLMETV-MMN-ALLVYEESRKLPSILNYDAGNLFI-Q----------SDSETISAKEEV-
AESIITKADNAQPNI-N-------------------DFEPDDSGDKDKPRRSKELDLISK
ESPLYIEESPETEEELGQASSIKSDFECSSKGPACLDTADKCQDSKDISDNYVDVPPVND
SSI--------TKLDKVLESQFSRE----NKGPTNRNCEENKH-----------RKKGKN
VYDSKKTDKEHYRRKREHSDTEEREKQN-S------KPGGH--CHKRRCSRSVET----N
KQSRHKQE-YCNGNKYRSSYTERNSPDFSRNSGKY--SHYRSRSR----------GR-EQ
-DRNRYYYSKEERNRSREKYYQDESWRWQKCRHYNDYYY-SH---AKGDSRERKFSHYNK
DFDKSS---QAC-SRSHKDYHYKSRRPHNSLSREEDVRHFS-HRADSRHCSF--------
AWQQPEKYSHERHIFPPVPPTHLNLEDLSPKNEKQNDR--KRK--YAESSES--E--TER
KS-RKIEKEVLDDQKMEKFKKAKKKKKSKDKYREKDY--KLYDSDFSVLHFDNDNRKRKK
K---KKKKKHTRKLKGFLE-----------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKV----SESSNSAACQKQPGSSTVPSSGDMDSASANWGA-VSSLE-APKHKITLG
PVPGAAVYSSSSVPDKSKPSAQKDQS-FS-------DGIAPPQKILFPAEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFLNSALQCLTYTPPLANYMLSHEHSKT--CHEHGFCMMCTMQSHIT
QVLSNSGNVIKPTAVIGDLRRIAKHFRFGNQEDAHEFLHYTVDAMQKACLNGSNKLDRHT
QATTLIYQIFGGYLRSRVKCMNCKGVSDTFDPCLDITLEIKAAQNLNKALEQFVKPEQLD
GENAYKCSKCKKMVPASKRLTIHRSSNVLTLSLKRFSNFSGGKITKDVKYPEYLDIRPYM
SQPNGDPIIYVLYAVLVHTGINCHAGHYYCYIKASNGHWYQMNDSIVSNSDIKSVLNQQA
YVLFYIRSNDTKNG-EHTHSIH-TPGQSSPRPVISQQVINS-RQGASGFIGPQLPPHMIK
-NSNHLNGTG--SLKETPSSSVASASNVT--LNRPASA-PPSTSIQNWTINRS-T--TPD
PSKKQKITISIHNNKLPTRQTLSQ--S-SLHNSLENLNKPVASSTITNSSAAKSTSNAPT
VSVA------MKVSKQTAPSES---------------CSKPLLNGNSKLNSS------TL
VPYGAESSEESDEE-SKGLVKEIGHSKSFNGILIGNVVSTLQNSCSSCQD---AKEAVSQ
HE-L-----PKNVTVNGAIS--IDND----------PEINGL-KFDESTCQVKPVKSTEV
SFSKANGLHGKIIPTVLPPVPEDRMLE--SFRYKQLK-SLSEEI----SATGLENTSEND
GHV-ETSVSGNSPVSCEKSSKVPANLSCNVQNSFT--------E---SDLETISTKEEI-
AESIVSKTENAHFDI-SGQCNTKK-ISMGVDDEFSKQCDTKD-Y-TDKIRGPQEVKMTLK
ESPLHIRGSAETAEKLGQIPFIKSDNECSSIKLTTLIIIDKCQETKESGNNYTDVPP---
--TN----DTSTKLDKILESNYS-KE--NDGLSGNEKCQENKDKKK----FKSHSPMKKR
ICSPKKLDKGHYRAKRQRSESVEQEKQTRN------K----P-DAKKRHSYNKES----T
KQGWYKQE-HSSGNKHKVMHRERDNPDNDRSLGKY--TNYRSRSR----------GKTDH
-EKNRYCHSKTXXXX--XXXXXXX-RRWDKCRYYND-YP-P--YAAR-GSRERKFIHGDR
DYDKSS---QSYNSRSYRDDYYTRRWNHEPVAK---EKHFSSSKIDYH---------WSA
PSQHSEKYSHEKCAPMSEE---NNSSFETSCHKSEYLNDRKRK--CASLESS--DSNMEK
KRRRSLQSEPMEEQRVKKHKKSKKKKKSKDKHREKD-DRLHQDSDISGAGSDSDIHKHKK
K--KKKKKKHTKKSEDFIATDLP-FHKNHGYT---VIK--SSDGNFAYTD----------
--ETRWKVSEK-------------------------------------------------
-----------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------HA

PF00443 // ENSGT00890000139343_4_Domain_3 (167, 425)

EGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGEITHSTH-SPGQSSPRPVISQRVVNN-KQAASGFIGPQLPSHMIK
-NPPHLNGTG--PLKEAPSSSMSSPSGNSS-VSRAGSV-NASTSVPNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHSGSLENPTKPVPSSTVTNSSAIQSTSSAPT
TAVS------SKVTKQMTPSES---------------CSKPVMNGKSKLSSS------VL
VPYGAESSEESDEE-AKGLGKEN----GLGT---------IESSNSSVQD--AEDDESSL
LEL------REPLALNGADS--TDSD----------LKENGL-SCDGASCQVPPALHSEN
PFSKANGLPGKLMPAPLPLLPEDKILE--TFKLSSKAKGSTEETRRGCSAPGTEEGPAGD
PGA-ELEAGSPS-PKSREKLETLTSLSSKLKAL--PPLDPSVKS----------TKEEV-
SENILARPEESLPSA-NTLCNSTK-NTTG-ADPLPKLCDPGD-LTDDQSRPPQAVSGALT
ESPR-ASAAVETAGSSSPSPPVHPEGACEHELL-VCVSRDTC-LDLEDPPGGTGMAA---
---EDSPS---PQVDEITE--DHSEGGPEQS--NGEKCEENKVGQK----VPDHSPVKEK
ISILRKVDRGHYRNRRERSSSGERARESGS------QTAEH--YHRKRHSSVRER----A
GQERYRTQ-HCNGGQPHPCPSQRLSPGEHRSLGRY--SRHHSRSR----------GASDR
-EWGRYHHSESEHSWGREKHYPDR-LRWDKCRYYHDRYA-P--YTAR-EAREWKPFHGPR
EY----AKAGPYGGRPYKDYYRGRQGYEPAAAKGKDRHHFGSPRAGPPHALLPYP-----
-----EKYPHEKIALVAED---TNCNLADRFHEHENAKSRKRR--YDSVENS--DGHVEK
KAWRGFQKDPLEEPKVKKHKKSKKKKKSKDKHRGRD-SRHQQDSDLSVACSDADLHRHKK
K--KKKKKRHSRKSEDFAKDLEPHLPKAASRETVDRFR--RTDGAFPLTD----------
--GLPLEGVGPFR--EKRKHLRMGSRD-----------DRCPLSECGQGKRRYLELRV--
-----------------------------------

MTIVDKA----SESSDPSTCQNQPGSSEAVSPEAMDTSSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSNSSVPDKSKQSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_2 (126, 171)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCKC------

ENSGT00890000139343_4_Linker_2_3 (171, 239)

SATRDNAKIF
KALLEPGRILARTGFD-------------------DFFCR--TLLSHHCL--FFRLDR

PF00443 // ENSGT00890000139343_4_Domain_3 (239, 425)

HT
QATTFVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAVQSVNKALEQFVKPEQLD
GENAYKCSKCKKMVTASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELAHSAH-SPGQSSPRPVISQRVVNN-KQAAAGFIGPQLPSHMMK
-NPPHLNGTG--PLKDTPSSSMSSSNGNSN-VNMASPV-NASTSVQNWAVNRSSV--IPE
HPKKQKITISIHN-KLPGRQGPSQ--PNLHSNSVENPNKPAPSSTITNSSAIQSTSTTSM
MSVS------SKVTKLTTPSEA---------------RSKPVMNGKSKLNSS------VL
VPYGAESSEESDEE-PKGLGKENGV----SA---------ISSSLSPSQG--AEDDEVSQ
HEL------QEPITLNGANS--VDSD----------PKENGL-PFDDADCQVQPALHSEN
PFSKANGLPGKLMPALLPSLPEDNILE--TFKLSNAVKASMDET----STPGAEENPPEE
QDM-EVEA-CSPSDDSEEKLETIESLSNKLKKVLSFP-DSSVVS----------TKEEV-
SENSSAKPDESS----------------SGDDQISKPCDPGD-LTDDQSKPSLDVKGTLV
ESPQ-DAVSAETVEKLSPAPLAHSEDGRECPIL-AYLGRDGG-KDAEDCPNSAGVCA---
---ERLPS---PQPDKTTG--DPSEGDAEQS--RAERCDESKVGQK----VRDRSPVKEK
ISSLRKVDRGHYRNRRARSSSGEHAKESRS------KTEDR--YYRKHRSYVRER----S
RQDRYTTD------QHHLNHGDRVSPGERHSLVRY--SYHHSRNR----------SGSDQ
-DWSRYHHAEGEHIWGREKYYPDK-MRWDKCRYYHDRYA-P--YTAR-EAREWKPFPGGR
EP----DRAGQRHGRLHKDYYRSRKDYEVA-AKEKVRHHLSSPRAGPPDPLPLYP-----
-----EKFSHDKIALGAED---NSCNLSDRFHEHDNVKSRKRR--FDDVENN--DSHIEK
KAQRSLQKDPLEEPKVKKHKKSKKKKKSKDKHRDRN-SRHQQESDLSVVCSDVDLHRHKK
K--KKKKKRHSRKSEDFFKDSELHLPKSSGYETVDRFR--RCEGGFLLTD----------
--GLLLEGAGPFR--EKTKHLRMENRD-----------NRGHLFEYGQGKRRYLEIRR--
-----------------------------------

MTVIGRA-----DSSDPSARQNQPGRSEAVSTGDVDTDSAGWSA-VSSLSDVSSHTLSLG
PVPGA-AYSDSAVSDRSEPSPPKDQ---G-------DGIALPQKILFPSEKICLKWQQTH
-GVGA

PF00443 // ENSGT00890000139343_4_Domain_1 (126, 229)

GLQNLGNTCFANAALQCLTYTAPLANYMLSHEHSET--CHAEGFCMMCIMQDRIT
QALNNPGDVIEPMFVINEMQRIASHFQIGEQEDAHEFLQHTVDAMQEACLSGSNE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------

MTIVDKV-----ESSDLSACQNQPGSSEAVSPGDMDAGSASWGA-VSALSDVSSHTPSLG
PVPGA-VYSNPAVPDKSELSPQKDQA-LG-------DGIAPPQKILFPSEKICLKWQQTH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALNNPGDVIKPMFVINEMQRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAPSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANSTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELT-HSTHSPGQSSPRPVISQRIVRQ-A--TSGF-IRQLPSHMMK
-NSPHLNGTG--PLKDTPSSSMSSPNGNPS-VNRASPV-NAPASVQNWSVNRPSV--IPE
HPKKQKITISIHN-KLPVRQGQSQPNH-H-SNSVEAPIKPVPSSTVTNYSAIQSTSNAST
MTIS------SKVAKPLSPSESCS---------------KPVMNGKSKVSSS------VL
VPYGTESSEESDEE-SKGLAKEN----GVGQ---------ITTAYSADHE--AEDDEAPP
HEL---QE---PITLNGANS--TDSD----------PKENGL-PLEGASCQVQPTLHSEN
PFSKANGLPGKLIPASLPSLPEDKVLE--TFKLSNKGKGSTDEI----SPPETEQGSSGD
LAV-ELEAAIAT-TGSHEKLDPITSLCSKFKKALL-SPDT--KS----------TKE-VA
SENSSAKPDESLPIV-NNLCNANK-TPTG-DDQLPELCDTGN-LTQDCSETPQEAQGLLI
ERLQ-DSAPTEAVEKLSPAPSVHSEAGY--------------------------------
---------------RTTG--THPEGGPEQSHSHRERCSESKVGQK----VPDHPPVKEK
ISSLRKVDRGHYRNRRDRSSSGERVQKSRSRSQSRSRTEDH--CHKKRRSYNRKH----S
KQECHTLE-HCNGSQHPLCYGDRVSPAERRSLSRY--SYHHSRTR----------NGADQ
-DWSRYHHLDSEHAWLPEKYYPKK-MRWDRCRYYPDRYT-P--YAVR-------------
---------ELSMKRPHKDSSRARKGWEPP-SRVRERTHFYSPRTGAAPPFPLHP-----
-----ERYPQEKVAFGADD---RGCGLSDRFHEHESMKSRKRK--YESRD-C--DSHVEK
KAHRSLPKE-LEEPKAKKHKKSKKKKKSKDKHQERD-YRHQLDPGLPVVYLDSDLHRHKK
K-KKKKKKRHSGKSVEFIKESGLQSPKASSYETVNHFQ--RPEGSFLLTD----------
--VLPVEDTGSFR--KKNKHLRMESRA-----------NRCHLLEYGQDSTCSTEA----
IPTQLKL----------------------------

MTIVDKA----SESSDPSAYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPDKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQNH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHPTH-SPGQSSPRPVISQRVVTN-KQAAPGFIGPQLPSHMIK
-NPPHLNGTG--PLKDTPSSSMSSPNGNSS-INRASPV-NASASVQNWSVNRSSV--IPE
HPKKQKITISIHN-KLPVRQCQSQ--PNLHNNSLENATKPVPSSTITNS-AVQSTSNAST
MSVS------SKVTKPIPRSES---------------CSQPVMNGKSKLNSS------VL
VPYGAESSEDSDEE-SKGLGKEN----GIGT---------IASSHSPGRD--AEDEEAAP
HEL------QEPMTLNGANSADSDSD----------PKENGL-LPDGASCQGQPALHSEN
PFAKANGLPGKLMPAPLPSLPEDEILE--TFKLSNKLKGSTDEM----SAPGAERGPPED
GDP-EPQPGSPA-AESLEELDAAASLSST-KKAPS-PPDPGTPT----------TKEGA-
WEALAAAPEELPPGAG-------Q-DIA-GDTAPPDLCDPGS-LTGDASPLSQDAKGMIA
EGPR-DSAMAEAPEELSPALPARSEEPCEQPLL-VHPSGDHAW-DGQDLPQSSGAPE---
-AAEGPLA---PVPEAAPA--GHPEGVAEPS--PGERGEDAA-APK----APGPSPVKEK
IGSLRKVDRGHYRSRRERSSSGEPARESRS------KTE--GHRHRRRGT----CPRERD
RQDRHA-------AEHHPGHGDRPSPGERGSLGRY--SHHHSRHR----------SGAEP
-DWVRHHYTEGEHGWGREKFYADR-PRWDRCRYYHDRYA-P--YA----ARDWKPFHGGR
EHERAG-----LHERPRKDHSRGRRGSEPA-R-ERERHRLGSPRAGAPHALAPHP-----
-----DRFSHDRTALVAG----DNCNLSDRFHEHENVKSRKRR--HDSVENS--DSHVEK
KARRSELKDPLEEPKVKKHKKSKKKKKSKDKHRERDS-RHQQDSDLSAACSDADLHRHKK
KKKK--KKRHSRKSEDFVKDSELHLPRAASLETVAQFR--RAQGGFPLPG----------
--GPPLEGVGPFR--EKTKHLWMESRD-----------DRCHLFEYGQGD----------
-----------------------------------

MTFVDRA-----DSSDSSDHWNQRGHSAAASTADLGAGSADQSAESSSLSDVSIHTLSLG
PVLGA-VYSESTVAGKSELSPPKDQGSYC-------DGIPPPQKILFPPEKICLKWQQSH
-RVGA

PF00443 // ENSGT00890000139343_4_Domain_3 (126, 425)

GLQNLGNTCFVNAALQCLTYTPPLANYMLSREHTKT--CHAGGFCVMCIMQAHII
QALSHPGDAIKPIAVISELQGIASHFRFGNQEDAHEFLQYTLDAMQEACLQGSYELDRHT
QATTLIYQIFGGYLRSRVKCLNCRGVSDTFDLYLDVTLEIQDVRSVNEALAQFVKPEQLE
GENCYKCSKCNSMVPASKSLSIHRPSNVLTLSLKRFSNCTGSKIAKIVKYPEHLNIRAYM
SQPSGEAMQYSLYAVLVHTGSKCCVGHYFSYVKASNGLWYQMNDFMVSPSDISSVLSQQA
YILFYIRTYDVKHGGEVTAHFPCHPCQFSSHPDTHQCTSTK-EQAAPGFNGPQLPSHMTR
-NLPYWNRIR--APIDTSSSSTWSPGGNPK-VNRPRPV-QASTSVPNREYNCSHI--QLV
SQ------------ALPALAT-ISPNH-AFSLGWEHPKGCWS-VQGLTYIQFLKTSQCTD
IALSCG----CFMW-NLQMNQSCRTQCIS-GQIPEHLQVHPVIIQHEHCIQSCHRHHWAV
SHFGKASATSHCDH--------------FSF---------YTILYFLGRV--MSTEINGN
NSITWGFT-PIDVRTCQGIA--TSMALEFVCIHLSEAMHALWPSTCALICSLKS------
PLLHSG------LLPCPQGC-RSDLL-SGDYLTSELPRERREAG----NVPGMEQSLFGD
LTA-ELEAVSVS-AGSHDEVDPIASLCEMFKKLLL-TPEISLKS----------MRD-VM
SETSSAITDVSLPFV-KKLCNKNQ-TSTG-ADPLYEPCDAGK-VTQDCSK----VNGL-P
ESLQ-HSGLAGTVEQLSPAPFTQSEGRCEPGPL-VSLRGDQCG-DTGAETQNIGECA---
---NALPS---TQPQSTPG--THPEGDPA--HSHAKGCSEVQVVQK----VPDHRT--QK
ISSRTRCDHEGYHYRHDCSSTGEDVKKSRDRS--------Q--SRRKWLCYARKH----N
KLECHAVQ-HCSANQDPLCCGDRVSPGKPCVLSRY--SSHHSQTW----------SGAQQ
-DWSPDCSSGREHRRLPEKSYPKK-MWWDQCRYL-NRYT-P--YEAR-------------
---------ERSVKRSHKDSSQARKGQELP-ALLCEWTGFHSPHTGASPPCPLHP-----
-----ECYPQEKAAFGADH---SGCSLSHRIRGRETMRSRKRR--YQSAESICNGGSTPK
KARRSLPRD-LEEPNK-----------SKAKHHEWE-HRCLLDTDLPVVQSDTQPCRYQK
----------KRHSENFGTEPGLHSPKTTSCETVDDVW--RPQGSSLLAD----------
--GLPVEGFGIFQ--MEKKPLKLDSRT-----------DWCQ---YGQVWIRRLCAPGFA
---LLFWDTGHLGSLCVSFSSSLCSDCSRAAPPPL

MTIVDKV----SESSEPSTYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVANHTLSLG
PVPGAVVYSNSSVPDKSKPSPQKDQX-XX-------XXXXXXXXXXXXXXXXXXXXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XHA

PF00443 // ENSGT00890000139343_4_Domain_3 (167, 425)

EGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRISRHFRFNE--YAHEFLXXXXXXXXXXXXXXXXXLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKANNGLWYQMNDSILSTSDIKSVLIQQA
YVLFYIRSHDVKNGGELSHSAH-SPGQSSPRPVISQRVVNN-KQAAAGFIGPQLPSHMIK
-NPPHLNGTG--PLKETPSSSMSSPNGNSN-VNRASPI-NTSTSVQNWPVNRSSV--IPE
HPKKQKITISIHN-KLPVRQGQSQ--PNLHNNSLENPSKPVPSSTITNSSAVQSTSNAST
LSVS------SKVTKQMTPGDS---------------CSKPVMNGKSKLNSS------VL
VPYGAESSEESDEE-SKGLGKEN----GVGT---------IESCHSSGQD--AEEDEASQ
HEL------EEPVTLNGAN--GTDSD----------PKENGL-SFDGASCQVQPALHSEN
PFSKANGLPGKLMPTPLPPLPEEKILE--TFKLSNRVKGSTDEN----STTGTDKAPKED
PDA-EAEAGGSA-PDPSEKLGAAPGLSSR-LKKAA-SLDPSINP----------TKDDV-
SEDTSAKPDEFLPSAN-------K-NT-TGDGQLSKLCDSGD-LA--NSPPSQDIKGTLT
ASPQ-DAVSIETTEKLTPTPSVNSDDECEHKLL-VYISREKCQ-EAEDLSKSTGTST---
-S----------------------------------------------------------
----------------ELPSLQLDRRESRS------KTED--HRHRKRCC----YSRERP
RQERPK-------PEHHPCRGERVIPCERHSLGTF--SHHHSRDR----------SGLEQ
-EWGRHHHSQSEHAWGWEKYHPDD-VRRDRCRYYHGRYA-P--YTVR-DSRDWKPFHGDR
EHGRGQ-----CSGRPHKDHCNSRRGYGPA-A-KKGRHHASSPRAGLSHAPPLYP-----
-----GKYSHEKIAFVSEE---NDCNLSDRFHEHDNAKSRKRR--YNSIENN--DSSAEK
KAGRSVQKDYLEEPKVKKHKKSKKKKKSKDKHRDRDSSRHQQDSDLSVAYSDADLHRHKK
KKKK--KKRHSKKSEDFFKDSELLLPKATSYETVDHVQ--RPRGSLPLTD----------
--GLPLEGAGPFH--ERTKHLRMESRD-----------DKYHLPEYGQGKRRLELRI---
-----------------------------------

MTIVDKA-----ESSDPSTYQNQPGSSEAVSPGDMDAGSASWGA-VSSLNDVSNHTLSLG
PVPGAVVYSSSSVPEKSKPSPQKDQA-LG-------DGIAPPQKVLFPSEKICLKWQQTH
-RVG

PF00443 // ENSGT00890000139343_4_Domain_3 (125, 425)

AGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKT--CHAEGFCMMCTMQAHIT
QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHT
QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLD
GENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYM
SQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQA
YVLFYIRSHDVKNGGELTHSAH-SPGQSSPRPVIGQRVVNSKQA-ASGFIGPQLPSHMMK
-VTLPSRASS--PLKEAGSHSLSAVGSWTGSRSCAGLG-LSDFSSKSWDVERKNY--SSK
GPRGPAAFCQSGK-SLPVRQGQSQ--SSLHSNSLEHPNKPAPSSTITASCAIQSTSSAPT
PPAS------SKVPKQTAPREA---------------CSRPVMNGRPRLSAG------VL
VPYGAESSEESDEE-AKGLGQEN----GRGL---------TESVCSPAPD--AEDGDASP
HEL------REPVALNGATG--PDSD----------PMENGL-PSDGAPCPGQPALHSEH
PFPKANGLPGKLMPAPLPPLPEDKILE--TFKLGSKAKGSAEET----RTPGSEERPLEH
LEA-ELEASRSPPGDGQRSGERVSSLSSKLKKASP-PSDPSIKP----------TKEEV-
SEHVLAEPEEAVSSV-STFCNPDK-DALG-DDQLPAPCDPGN-LTDDQSKPSPDVGGTLP
ERPP-DPVAAEATGRLSPVPSVPSEGDREPEPL-GHSSRDRG-SEAEGPAKSTGVST---
---DEVPS---PQLDMIT-E-NHPEGPPERS--SSERGEDSKAGHK----APEPCPVQEK
VSSLRKVDRGHYRSRRDRSSSGERARESRS------RTEVQ--HRRKRPHREHER----P
RPERPRLE-PCALAP---------QPPRPTSLARL--GHHHSRSR----------GAPDQ
-EWGRYHHAEGEHAWAREKYYPDR-LRWERCRYHHDRSP-L--YPGR-EPRDWRPFHAER
EY----ERAGPYGGRPYKDHYRGRKGYELA-AKERDRHRFSSPRAGMAHAPPPHPA----
-----AKYAHDRLGFGAED---GSCDLATRFHEHDNVKSRKRR--YDSLEN---ESHVEK
KAWRSLQKDPVEEPKVKKHKKSKKKKKSKDKHRDRD-SRHQQDSDLSVAHSDADLHRHKK
K--KKKKKRHSRKSEDFGRDSEPRLPKAASCETLDHFR--RAEGAFPLAD----------
--GLPLEGAAPFC--EKTKHFRMESRE-----------VRCRLSECGQGK----------
-----------------------------------