Query Results 

------------------------------------------------------------
---------------MPQACTMPIVDKLKEALKPGRKDSAKDGELRKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASHPKSGDEP-QAKRQGTGSERLSGSSNDG
VPAPQKVLFPTEHLSLRWERIFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATVQCLTYTPPLANYLLSREHS
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPSSKKSPEGPISRGGST-LPSHP-SMIPDHTKKNAGNGVTSSPPAA
KPQGAVPMRKPQ-TPEEMGVPVSRNGSMPGPKLQNGCVPAR---------SPLGSP----
--PLRLSHTPTPMPTLLDENGKKVKKQVPLQLCSLSLRTSQGSPSTS-----E---PGSR
RQSSWDTRDTVPSTSLKLLAEATASGHGLKGEGKN---ADLEKGT------SGSSSPE--
-----NSSSRSPKVPQAPKGGAAQVCDSQGTNCPTAGHSKALPNGLDSKMVKLKAPVLGS
T-AIEPVSLMSPPPAKKLALSAKKAS-TLRRATGNDLRSPPPSPLSDLTCPMTATHPVVA
STWPVSKSRAVSP------------APRSSSCPKSPVSTPSA-SLSSSNP-----CPPQS
CS-STWTALPQVNGDLMSPSHQLLLLEASEAPRSPSRKRNGSHVGEPQMRGSEACIPQLL
GGAAAAPRKKRKRKRR--KGPEGM---------AMAIPQEQM-QRPPWSPEN--K--KKG
QAELPAH--PQVEEGTQPQ-----------VDHILDSQHVSNRKRKRKGA-EGLCEEVGL
LQGPPWHSCIST------------------------------------------------
-DHGEPETRAESPRKKKRKK--RKPETQQE------EEENKHPEDPRSTKRSVTT-----
-----------------GLELSVNSQLAGDRPGL---------GQPPLGLWNRDQDSDVV
QELLKYSSDKAYGRQVLTWDGEPSAVSRDAIEDSRLARTRTVVDDWDEEFDRGKEKKMKK
FKREKKRNFNAFQKLQSRRNFWSATHPAKATSLSSRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRRDSADDGELGKLLAASAKKVLLQK
LEFEPASKSFSYQLESLKSKYVLLNPRTEGAGCHRSGDEP-PARKQG--SEHAYESCSDG
VPAPQKVLFPVERLSLRWGRVYRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTVQCLTYTPPLANYLLSKEHT
RGCHQGSFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLRKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDMALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKRKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSSVHASNIKV
VLNQQAYVLFYLRIPGSKKSPEGSISRMASS-LSSRP-SVVPDHVRKNGSNGTTASPVTG
KRPDPVTMKKPQ-TPEELGVPIARNGSVSGLKSPNGYAPPK---------PPLGSP----
--SPKVCKTPTHAPAILDEPGKKVKKPASLQHFSPPPSAS-------APGGSR---NEGR
RPGSWDGRAAV-STSLQAPAAGTPNGLGPQAGDEG---PTPERGGS--------------
-----SLEHPTSKPPQAPRSGATRLGDSQGTHSATAGPTKVLPAQQDAEPEKAKCPILSG
A-SPEPANAMSPPPAKKLALSAKKAS-TLRRATGNDLRPPALSPSSDLTYPRKPTHPVVA
TPWPVHAMRAVSP------------APRPSSHLKPLFGPCP--PSLSSSPQPLGTSDPQS
CS-PASAPLPQVNGAFRAPPYQLP--EASEPPQSLGKKRKKTRVKGGD------CVSETY
TALAA-P-PGKRRKRK-RKHTG-------DVD-ATPSQDEQT-PGPPWSPGR--R--KEG
RAEPLAD--RSEEEGRHQPESGQRLENNWPVRCMTNGPHVSSRKRRRKGP-ESCDGEDCL
PGDPPWHGSCTPS-----------------------------------------------
-DVVQPETVATSPRKKKKKK--KKQEPRQE------VEEK-EPEGQRGPTVPRH------
-----------------RPLPAVNGQAPRGPTGL---------GPAPLASWDRERESDVV
QELLKYSSDKAYGRKVLTWDGEVSAVSQDAVQDSRLARTARVIDDWDEEFDRGKEKKLKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKASSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPSRKDSADDGELGKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPRVEGAGRHRGGDEP-QARRPG--GEHVNESRGDG
VPAPQKVLFPLERLSLKWERVY

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLHNLGNTCFLNSTVQCLTYTPPLAGYLLSKEHS
RSCRQGSFCMLCLMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGSQEDAHEFLRYT
IDAMQKACLSGCAKLDRQTQATTLVHQIFGGYLRSR---SVCRSVSDTYDPYLDVALEIR
XXXXXXXXXXXXXXXXXX------------------------------------------
------XXXXXXXXXCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITK--GYPEFL
NIRPYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASNGQWYQMNDSLVNSSNIKV
VLNQQAYVLFYLRIPGSKKSPEGSVSRPVSS-LSSRP-AVVPDHGRRSVANGAVSSPLAG
KRLDPVTMKKLQ-TAEEIGVPVSRNGSALSLKSQNGHVPPK---------PPSASP----
--SPRLPKTPTHLPTILDEPGKKVKKSAPLQYFSSPLKASQGLHGARDPSRC-----EGR
RP-------GAITTSPQVPAAVTANGHGPKGRHEKG--------D------SSSSSP---
---EHSTSSDPAQAPK----SGARVCDPQGTSPSAAGPSRALPSGED-TMAKPRSPVLSS
A-ATEPASTMSPPPAKKLALSAKKAS-TLRRAAGSDLRAPPL---SGLTHPRKATHPAVA
CTWPVSTSRALSP------------APRSSGHLKPPLSLHSV--TVPSSPQPLRTSGPRN
P--FTSAPLPQVNGGFGAPPHQPP--EADEPPRSPCKKRKRKRSAETRGPGSEVGEA---
----AAP-PGRRRRKR-RKRPGDT--------DAAPPQEGQPQ-GQHQGPEH--------
---RSEGRAQLGEEGRQPPA------NGWQAGCGTDGPHVSPKKRRRKGA-EGPGGEDRL
HQDPPWHSCSPS------------------------------------------------
-DVTEPEATAASPRRRRRRSR--KQS-RQE------AAGDERADAARGEGQRGPAVPG--
----------------GSPLPAVNGRSPGDHAGL---------EQTPLASWSGEQGSDVV
RELLRHASDRAYGKEVLTWDGEVSAVSQDAVRDSVVARSTTVLDDWDDEFDRGK------
-------------------------------------

PF00965 // ENSGT00890000139343_3_Domain_0 (1, 79)

MFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGRMHITLCDFIVPWDSLS
STQKKSLNHRYQMGCECK

ENSGT00890000139343_3_Linker_0_3 (79, 206)

CCAMPIVEKLKEALKPGRRDAADDGDLGKLLASSAKRVLLQR
IEFEPARRSLSFQLDALKSRYVLLSPRAAGAGRPRSAEAP-QARRPG--SENALEGGSDG
VPAPQKVLFPTERLSLSWERVFRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTVQCLTYTPPLANYLLSQEHA
RNCHQGGFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLRKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSLCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYLCAKSCSLLPAWAHWSLLTLTRHVHVLLVLWLHCSH
WSSCWCCCVFLRLRWCKKKVPASKRFSIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGEPVTYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPQGPISRAAS--FPGRP-SVTPDPSRKNFSHSTVASPLPG
KRQDSVPVKKLP-ATEELGVPVSRIGSVLGLKMQNGHGPPK---------LPPGAP----
--PPRLSQTPTHVPRVLPEPAKKVKTPSPPQPLRPSLRTPQGSPGPSSKCGA----PGGR
RQGSWDDGSAALSTSPKLPAEATANGHGPKRGDGH---AN-----------LSSSSP---
---EHSAESDSTKAPQTPRGGAARFCESQETHCPAAGHSKVPPGGADPKVARLKSPVLGS
V-TSEPASATSPPPAKKPALSAKKAS-SLRRASSSDLRSPPPSPFSDLTYPMTATHPAAA
STWPVSKPRAVSP------------AAPPSSRPKPPISPHSA-SPSSTSPQPPGTPEPQN
RP-STSATPPQASGGLVSPSSPLL--QARRAPQSSSKKRKRTCSGEPPGLGSEAPVAWHL
GVAAAAPRRKKRRRKR--KHLQEEAAA--------LVQAQE------------------C
AAERPAS--PLGEAAAQPRA------TGQQVGHVLSGQHSR--KRRRKGA-EGPGREGSL
PLGPGQHSSCSPA-----------------------------------------------
-SCDEPEPRAESPRRRKKKKR-QKE-----------AEEREHSTGQRSTRPSDTAVPG--
---------------LSPPPPLVNGQLPGDHEGA-----SLGLGQAPLVCWDREQKSDVV
QELLRYSSDKAYGKKVLTWDGEVSAVSRDAAEDSRLARTRSVVDDWDEEFDRGKEKKVKK
FKREK-RNFNAFQKLQSRRNFWAVTHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDLADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRHKSGDDP-LARRQG--SEHTYEGCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRLP-------TSDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRL-SVIPDHSKKNIGNGIISSPLTG
KRQDSGTMKKLH-TTEEIGVPISRNGSTLGLKSQNGCVPPK---------LPSGSP----
--SPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSNLSSSR---PGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGPKGNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTPRSGAAHLCDSQETNCSTTGHSKTLPSGADSKTVKLKSPVLSS
T-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVHRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGTSEPRS
CS-SISTALPQVNEDLVSLPHQLP--EASEPPQSPSEKRKKTFVGELQRLGSETRLPQHI
REATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPGSPAH--R--REG
QAQLPAV--RWQEDGTQPQV------NGQQVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SRSPM-----------------------------------------------
-GDGDPEAMEESPRKKKKKK--RKQEPQRA------VEEDGHLEGPRSAKPPDAAVAE--
---------------SSSRAPSANGWCPGDRMGL---------SQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRQARTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKAEGASRPKSGDEL-QVRTQG--SEYI-YDGGDG
VPAPQKVLFPMERLSLRWERVFRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTIQCLTYTPPLANYLLSREHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNSGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMDDSLVHPSSGKA
VLSQQAYVLFYLRIPRSKKSPEGPVSKTVHS-LPSRP-GVAPDHTKKNAGNGIVSSPLTG
KQQDSVMMKKPH-TTEETGMPISRNGSGPVLKSQNGCVLPK---------LPMGAP----
--SPKLSQTPTHMPTILDEPGKKVKKSVPL-HFTPSFKTSQGPSSASILSSSK---SGSR
KPGSWDRDA--HSTSPKFLAKATANGHGPKGSDES---SDPERGN------SSSSSP---
---EHNASSDSAKGSQTPKSGAAHFCDSQETNYSANGHSKALPNGADAKMVKPKSPVLGS
A-APEPASIMSPPPAKKLALSAKKAS-TLRRATNSDLCPPPPSPSSDLTHPMKTSHPIVA
STWPVHKIRAVSP------------APRLPKHPQPPFSPNS--TLLSSRPQPRGMSEPRS
CP-SALIALPQVNRDLVSLSYQLP--EADESPQIPSEKRKRNHTGELQGPGSEMCLPQHL
EGAAAAPASHRKRKRKKRKRPEDVA--------TAISQDEQIRGCP---SRL--EYREKG
QAELPAD--RQERKGTQPQV------NGQQMGHVMGSHHVNNRKRRRKGV-EGLGEED-V
HQDPPWH-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRRDSADDGDLGKLLAASAKKVLLQK
LEFEPASKSFSYQLESLKSKYVLLNPRTEGARCHRSGDEP-PARRQG--SEHAYESCSDG
VPAPQKVLFPVERLSLRWGRVYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTVQCLTYTPPLANYLLSKEHT
RGCHQGSFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLRKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHASNIKV
VLNQQAYVLFYLRIPGSKKSPEGSISRTASL--SSRP-GVVPDHVRKNVSNGTAASPMTG
KRPDPVTMKKPQ-TPEELGVPIARNGSVLGLKSPNGYAPAK---------PPLASP----
--SPKVCRTPTHAPAILDEPGKKVKKPASLQHFSPPPSAS-------APGGSR---SEGR
RPGSWDGRAAV-STSLRAPAAGTPNGLGPQAGDEG---PTPERGGS--------------
-----SPEHPTSRPPQAPQSGVTPLGDSQGTHSVTAGPTKVLPARQDAEPEKAKCPVPSS
T-SPEPANTMSPPPAKKLALSAKKAS-TLRRATGNDLRPPALSPSSDLTYPRKPTHPIVA
APWPVRAIRAVSP------------APRPSSHLKPPFG-PCP-PSLSSSPHPLGTSDPQS
CS-PTSAPLPQVNGAFRAPLHQLP--EASEPLRSLGKKRKKTRVKVGGRV-SETCTAVA-
----AQ--PGKRRKRK-R-------KHMGDVD-ATPLQDER-TPGPPWSPER--R--KEG
RAEPPAD--RSEEEGRQQPGSGQRLENSWPVGCMTNGPHVSSRKRRRKGL-ESCDEEDCL
PGDPPWHGSCVPS-----------------------------------------------
-DVVQPETVATSPRKKKKKK--KKQEPRQE------VEEK-EPEGQRGPAVPGCSPL---
--------------------PAVNGQAPRGPTGL---------GPAPLASWDRERESDVV
QELLKYSSDKAYGRKVLTWDGAVSAVSQDAIQDSRLARTATVIDDWDEEFDRGKEKKLKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKASSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRRDSADDGELGKLLAASAKKVLLQK
LEFEPASKSFSYQLESLKSKYVLLNPRTEGAGCHRSGDEP-PARRQG--SEHAYESCSDG
VPAPQKVLFPVERLSLRWGRVYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTVQCLTYTPPLANYLLSKEHT
RGCHQGSFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLRKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKRKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSSVHASNIKV
VLNQQAYVLFYLTIPGSKKSPEGSISRMASS-LSSRP-SVVPDHVRKNVSNGTLASPVTG
KRPDPVTMRKPQ-TPEELGVPIARNGSVSGLK----------------------------
---------PTHVPAILDEPGKKVKKPASLQHFSPPPSAS-------APGGSR---NEGR
RPGSWDGRAAV-STSLRAPAAGTPNGLGPQAGDEG---PTPERGGS--------------
-----SLEHPTSKPPQAPRSGATRLGDSQGPPPATAGPTKVLPAQQDAEPEKAKCPILSG
A-SPEPANAMSPPPAKKLALSAKKAS-TLRRATGNDLRPPALSPSSDLTYPRKPTHPVVA
TPWPVRAMRAVSP------------APRPSSHLKPLFGPCP--PSLSSSPQPLGTSDPQS
CS-PASAPLPPRNGAFRAPPYQLP--EASEPPQSLGKKRKKTRVKGGD------CVSETY
TALAA-P-PRKRRKRK-RKHTG-------DVD-ATPSQDERT-PGPPWSPGH--R--KEG
QAEPPAD--RSEEEGRHQPESGQRLENSWPVRCMTDGPHVSSRKRRRKGP-ESCDGEDCL
PGDPPWHGSCAPS-----------------------------------------------
-DVVQPETVATSPRKKKKKK--KKQEPRQE------VEEK-EPEGQRGPTVPRH------
-----------------RPLPAVNGQAPRGPTGL---------GPSPLASWDRERESDVV
QELLKYSSDKAYGRKVLTWDGEVSAVSQDAVQDSRLARTARVIDDWDEEFDRGKEKKLKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKASSLSYRR

------------------------------------------------------------
-----------------------------------------DGELGRLLASA--KKVLEK
IEFQPASKSFSYQLESLKSKYVLLNPKTEGATRHKGGSEP-PIRRQG--GERSYDSCTDG
VPAPQKVLFPTERLSLRWERVY

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLHNLGNTCFLNSTVQCLTYTPPLANYLLSREHA
RNCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGSQEDAHEFLRYT
IDAMQKACLNGYAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------HCKKKVPASKRFSIHRASSVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQGSGEPVTYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHASNIKV
VLNQQAYVLFYLRIPSSKKSAESPICKAAST-LPSRS-SSTPDPLKKNI-SGVASSPLTS
KRQDPMTPKKLQ-AVEELGVPVSRNGSLTGLKPQNGAVPQK---------PPSGTP----
--SPKLSKTPMHTPTILDEPGKKVKKCAPLQHLCLSPKTSQGPCGTSNWSGGG--SRSES
RRPGWDSKDTVPSTSPKLLARAVTNGHGPKTRDQS---PDLDTGS-------SSSSP---
---DHS---ADSATPQTPRSGAARLCNSQETDCPANGHPKAIPRGGDPKMVKLKSPTLSN
M-ATEAAS----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGKLLAASAKKVLLQR
IEFEPASKSFSFQLESLKSKYVLLNSRAEGASHHKSRDEL-QARKPG--TERVSGSGGDG
VPAPQKVLFPMERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVCRVGST-LPSRP-SVIPDHSKKNPGNGVVSSPLMA
KRQDSVMR-RLQ-SPEEVGAPVSRNGSMPGLKLQNGCVPAK---------APAGSP----
--SPRLTPTPTHMPTILDEPGKKVKKPAPPQSLTTPPTTSQGSPGTS-----E---SRNQ
RPGSWASRDTIFSTSPKLLAKAFANGPRLTGEGNG---VGLEKGA------SSGLSP---
---EHPASRGPAKAPQTTEGRAAHFCDSQGTDCPTAGPSKALLNGVDPKIVKLKSPALSS
T-ATEPTSLMSPPPAKKLALSAKKAS-TLWRATGNDIRSPPPSAFSDLTYPMKATHPVVA
STGPVSKTRAVTP------------APRPS------IHPHSA-SLSSSSAKPLGTSEPQS
CRSSASMPLPQVNGHVVSHLHQPP--EAIKALHSPSRKRKKTPNGDSQRLGIDTHLPQCL
EGAPAAA-RRKRKKKK---------KCLEDVAHTAPQQEGPS-QDQPSSPRG--R--K--
------------EEGTHPQV------NGHQVSHILDSHHVSSKKRRKRKRSEGLSQEATL
TQNILQHGCSPA------------------------------------------------
-DHYETEVRTDLQRKKKRRK--RKHESQQE------EEENEHPEGQRSPRPSVTSS----
------------------PELRVNGHLSSDRLGL---------GQAPLVAWNRDQEPDVV
QELLQDSSDKAYGKKVLTWDGEPSAVSQDAIKDSRLARTQTVLDDWDEEFDRGKEKKIKK
FKREKKRNVNAFQKLQSRRNFWSVTHPAKVASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDAELGKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRPKSGDEP-QVKRQG--SERFSGSSSDG
VPAPQKVLFPTERLSLRWERIFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATVQCLTYTPPLANYLLSREHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPEGPISRASCT-LPSRQ-SVVPDHTKKSAGNGVTSSPTTA
KLQDPVLLRKPQ-VPEEIGVPVSRNGSMPGPKLQNGCVPAK---------SPLGSP----
--PPRLSHTPTHMPTLLDENGKKVKKQVSSQHCSPSLRTSQGSPGTS-----E---PGSR
RQSSWDSRDTVPSTSLKLLAEATASGHGLKGEDKN---ADLEKGT------SSSSSP---
---EHSSSSS-PKVPRASEGGAAHVCDSQGTNCPTAGHSKALPNGLDTKIVKLKSPVLGS
T-AIEPMSLMSPPPAKKLALSAKKAS-TLRRATGNDLRSPPPSPLSDLTYPMTTTHPVVA
STWPVSKSRVLSP------------APRSSSCPKPPTSTPSA-SLSSSIPQAPQTSEPQS
CS-STWTALPQVNGDLMSPSHQLL--EASEASRSPSRKRHRSPAGKPQMLGSEAGISQLL
GGATAMP-RKKKKKKR-R-----KGAE-GMTT-AIPQEQVQGPPW---SPKN--K--KKG
QVELPTH--PWEKEGTQPQV------DSQQVGYVLNSHRVSSRKRKRKGT-EGLCEEVGL
LQRPPWHGSCTSTDHGER------------------------------------------
------ETRAESPRKKKRKK--RKHEAQQE------EEENKHPEDPRSTKPSVS-TGI--
--------EL-----------SVNSQLAGDRPGL---------GQAPLGPWNRERESDVV
QELLKYSSDRAYGRQVLTWDGELSAVSRDAIEDSRIAQTQTVVDDWDEEFDRGKEKKMKK
FKKEKKRNFNAFQKLQSRRNFWSVTHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRRKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPMERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPSRP-SVVPDHSKKNVGNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGSTLGLKSQNGYVPPK---------LPSGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDAVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTARSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGMSEPQS
CS-SFSTALPQVNEDLVSLPHQLP--EASEPPRSPSEKKKKTFLGELQRLGSETCLPQHI
REATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-TQPGSPTH--K--REG
QAQLPAV--RRQEDGTQPRV------NGQPVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQRV------VEEDGHLEVLRNAKPRDAAVPE--
---------------SSSHTPSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDSIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLAASARKVLLQK
IEFEPASRSFSYQLESLKSKYVLLNPKSEGAGRHRSGDEP-QARRQXXXXXXXXXXXXXX
XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXH

PF00443 // ENSGT00890000139343_3_Domain_3 (245, 551)

QGSFCMLCVMQNHITQAFANSGNAIKPVSFIRDLKKIARHFRFGSQEDAHEFLRYT
IDAMQKACLNGCAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------RCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASSGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSRKSSESAVSRPGSS-LASRP-GVAPDPIRKSIGNGIASSPLPG
KRQDSGTVKKLP-TPEEVGIPVSRNGCVPALKSQNGYTPPR---------PPMGSP----
--SPKFSQTPTHAPPVPDEPGKKKKP-ASL---QFSPRASQGPSGTSSPSSSK---SGGR
RQGSWDGRDAVLSTSPKLPAGATANGHGPKGNAEG---SGPERRG------SCSSSP---
---EHSA-DSSTKAPQAPRSGATPLSDSQGTNCSTAGDSRALLNGAECKMTKPKPPVLGS
T-APEPASTMSPPPAKKLALSAKKAS-TLRRATGSDLRS-PPSPLSGLTYPMEATHPAAA
STWPVSRTRAVSP------------APEPSSRPKPPISPHSA--SLSSSPRPPGTSGLPS
CC-STSTALPQVNGDPARLSRQLL--EAGEASRTPSKERRKAGLGELQGPDRKP--ARHR
DAAATL--PGRRRRRR-RRRLEAM---------ATATQQEQT-QRQPWSPES-----KEG
QAWLPGD--RREEEGGQPQV------NGWEAGHVADGPRLSSRKRRKGAE---------G
LQDPPWHSHPPVNS----------------------------------------------
----SQTEEAGSPRRKKRKR---KHESQEA-------DEEEH-ASQGHTRPGVTV-----
------------GPELSGHSAPVSGRHPGAHRWL---------GQAPLVSRSSERESDVV
QELLKYASDKAYGRR---------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPRTEGSTRHRSGDEL-PARRQG--SEHAYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RNCHQGSFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALEVFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPSSKKSPEGPISRAGSS-VPSRP-SVVPDHTKKNVGNGIVSSPLAG
KRQDSVTMKKPH-ATEEIGVPVSRNGSVPGLKSQNGYIPPK---------PPLGSP----
--SSKLSQTPIHMPTILDEPGKKGKKSTSLQHFSPSLKTSQGLPGTSNSSSSK---AGSQ
RQGSWDGRDGVLSTSPKLLAEATANGHGPKGSGES---SDLERRD------SSSSSP---
---EHSASSDSAKAPQTPKGGAAHFCDSQETNCPTAGHSKAPPSGADPKMVKLKSPILSN
T-ATEPASTMSPPPAKKLALSAKKAS-TLRRATGNDLRPPPPSPFSDLTHPMKTSHPVVA
STWPVCKTRAASP------------APRPSSRPQPSFR-PHS-TSLSCSPQPPGMPEPQS
CY-SALTALPQVHRDFVSLLHQLP--EANKAPLNPSEKSKKTLVRELQRPSSETCLPQHI
EGTPAAP-HGKRKRKK-RKRLED----------TAALLEGQTQ-RWPWSPEG--R--RKG
QAELPAD--RLEEEGVWLQG------NGQQAGRVMDGHHVNSRKRRRKGA-AGLDKEAGL
HQYPPWHSCSPT------------------------------------------------
-DCGESETMAGSPRKKKKKK--RKQESQQE------VEENQLPENQRNARPCDTAVP---
--------------ESSGHSPPVNGRHPGDCVGL---------GQAPLISRNREQESDVV
QELLKHSSDRAYGKKVLTWDGKMSAVSQDAIEDSRLSRTETVVDDWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSTDDGDLGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGSSRHRNCEET-QIRRQG--SDHGFENCSDG
IPAPQKVLFPMDRLSLKWERIYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHT
RNCHQGGFCMLCVMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYI
IDAMQKACLNGYTKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPIMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPEGPIAKTASV-LPSRANSVVPEHIKKNISNGVVSSPLIG
KKLDLVSMKKQH-TAEENGVPVSRNSFMIGSKSQNGNVQLK---------LPLGSL----
--SPKLSAKPIHGPVILDKLGKKVKKPLSLQHLSPSLKVSHGLNGTSSLSSTK---LESR
RQGSWENKNAMLATSPKLLPEVTVNGHGPKGNGEC---SDPKRKD------SISSSP---
---EYSASSETARGPETPKNGVGCFYTSQETDYSAGERTKEPPGGEDSKMVKLKSPVLTN
T-ATEPTSIMSPPPAKKLALSSKKAS-TLRRATGNDLHSPPHSSFADHTYPTKITHPASA
SSWPVSKIRAVSPPKSSSPLKSSFNS-----------YSIKA-SPLLSSFRPSGMTEPHS
CS-FASNPLPQVNGDNMSSSHQQQ--GTSNIPQSFSKKRRKKHVSEDRSYRNPEEEISQG
NGEAAADLSHVKKKKK-RKHTEENHRSWTEVA-TSLTQEEQIQ-RSIWNRGL--G--RKY
GLDVTVD--RVEE-EKNQEM------NGSHIGVVTDAHFCKKKKEKKRKRMEECNEEHFH
YQKSSL------------------------------------------------------
-DRDEPESVIESPRKKKKKK--RKQNSEQE------VEENEHQKHQRKDCQSDHKVIL--
--------KE--NSVCKDMS-NQSPVVNGQHPGNIASYLFLEKKQAPFQLWNKEKESNVV
QELLKYSSDKAYGKKVLTWDGEVSAISQDAIQYSRLAQNETVIDDWDKEFDSGKEKKIKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKVTSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGRLLAASAKKVLLQK
IEFEPASRSFSYQLQSLRSKYVLLNPRPEGTARPR-GDEP-PARRQG--CERVYESGGDG
VPAPQKVLFPVERLSLKWERVY

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLHNLGNTCFLNSTVQCLTYTPPLANYLLSREHA
RSCPQGSFCMLCVMQNHLVQAFANSGNAIKPVSFIRDLRKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGYAKLDRQTQATTLVHQIFGGCLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDALSGENAYMC-A--------------------------------
--------------RCKKKVPASKRFTIHRASNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGEPVVYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPEGAISRAGSA-LSGRP-GGAPDHGRKSVSNGTLSSLLPG
KRPDPVAMRKLQ-APGETGVPVSRNGFLSGLKAQNGHIPPK---------LPLGSS----
--SPRLSKAPTPLPTILDEPGKKVKKSAPLQHLSPPLKTSPGSHGAS----SR---GDSH
RPGSWDGRGAGLSTSPKPVPAATANGHRPAGIAP-------DRAA------SSSSSP---
---EHSGSSDPAQGPPTPRSGAARFCDSQGRT-PTAGPPRALLNGEASTVVKPRAPALSN
M-AAEPANAMSPPPAKKLALSAKKAS-PLRRAPGTDR-APPLPPLSDLTHPRKATHPAAA
CARPVGASRAVSP------------APGSPSVPKPPH----A-AS-----------LPSS
PPNSACAPLPQVNGGFRAPPHQPEASEPS---RAFTEAP---------GRGP---EPSTE
AGEAAAP-PGKRRRKK-RKRP-------EDTG-IARLQAGQAQ-GQHWSPER--R--PEG
GVKRPAS--SLEAEGGQQPVNGRGLVNGWPVGCRTDSPHMSKKRRKGVDG-LGGEGEACL
RQDPPRHRSCSPS-----------------------------------------------
--DAEPEATAASPRKKKKKK--RKPESRQE------GEEEEHPGGWRGPAVPGSSPA---
--------------------PAVNGQSPGDLAGP---------EQTPRHSWSRERGASVV
WELLECASDKAYGKKVLTWGGEVSAVSRDAMHDSRLARAATVIDDWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQNRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSVEDGDLGKLLAASAKKVLLQR
IEFEPASKSFSYQLESLKSKYVLLNPRTEGASRHKSGDEL-QARKPG--TERASGSGGDG
VPAPQKVLFPTEQLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKSDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVTYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHPSNAKV
VLNQQAYVLFYLRVPSSKKSPEGPISRAGPT-IPSRP-SVIPDHPKKIPGNGVASSPLMA
KRQDSVLMKKLQ-TPEEVGVPVSRNGSMPGLKSQNGYVPAK---------ASMGSPSPKF
TPTPKLTPTPTYMPALLEEPGKKVKKLASPHSLTSSLHASQGSPGTR-----E---SRSQ
RPSSWESRDSVLSTSPKLLAKAIANGHKLKGEGSD---VDPEKGP------SNSSSP---
---EHSASSVPAKAPQTPEGRAAHFCDSQGTNSPTAGHSKVLPNGTDPKMAKLKSPALGS
TTTTEPTSLMSPPPAKKLALSAKKAS-TLRRAIGNDLRSPPPSPFSDLTYPMKATHPIVA
STQPVSKIRAVSS------------APQPSTFPN----PHSA-SLSSSSPKPPGTSEPQS
HY-SAWTPLPQVNRDLTSSLHQLP--EATEALQSPSKKRKKTPNRDPQRLGIDTRLPRCL
TGAAK----------N-------KKWCLEDVA-VAPWQEDQAQ-GQPWSPR---------
---------SRKEEGTQPQV------NGHQVSHVLDSHHVSIRKRRRRKGSEALSKEATL
SRDPPRHSCSSA------------------------------------------------
-HHSESETWTQSPRKKKRKN--RKHESQQE------EGENEHSEGQRSPLPGAATV----
------------------IEWSVNGQLPGDRLGL---------GQAPLVPWNREQEANVV
QELLQFSSDKAYGRKVLTWDGELSAVSQDAIRDSRLARTQTVVDDWDEEFDRGKEKKMKK
FKREKRRNFNAFQKLQSRRNFWSVTHPAKVTSLSYRR

------------------------------------------------------------
----------------MPGPAMPIVEKLREALKPGRREPSEDGELGRLLAASAKKVLLQR
IEFEPASRGLSGQLELLRGKYRPLNASAGPAAPRPPPPEG-PSRKHG--GD---HGAGDG
VPAPQKVLFPAERLSLKWERVQRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATLQCLTYTPPLACYLLSKEHS
RACHQGGFCMMCVMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGSQEDAHEFLRYT
IDAMQKACLSGCTRLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVSLEIR
QAANIVRALELFVKSDVLSGDNAYMC-A--------------------------------
--------------RCKKKVPASKRFTIHRASNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHCSNIKV
VLNQQAYVLFYLRIPGPRKGSEGPIAKA----TPSHS-PVVSDQTKRTSTNGPLPSPLLG
RSPEVLPGRKLS-GPEEIGVPVARSTLGVGPKLPNGSAPPK---------PPTGSP----
--SPKLPLRATQVTPSDDT-ARRPKK-PPSPQRPPAPKASPGPY----SSGAA----HPP
QQSPGDGTRSPTSPSPGTP--------------------QRGSCG------SAAPSP---
---AHTAAGDAAKAAPKAKSGAGGLSPPQDTDCG-----ADLPEG-------SRLAKLKS
A-ALEPGSTTSPPPAKKLALSAKKGS-TPRRVSRSDGRV-QPAG---LAFPTAT-----A
QPWPCGRPR----------LPSALPLPSPDT-PAFSFT-PSA-A-----SQLPA------
--------SPLTNGAHPSHHHPTL--SGEHGPSPTSTKKKQRKQQQSKAGGSSHAMAVNG
CDEGCSP-PRK---RR-N-----IAPE-GSI----PGKEAAGTGREERDPRG--S--PS-
--TEPI----------------------SPLKKKKRKRRLQETEERSSGA-QPLGSSRKA
DTEPSWTKQQQSPEPSEGESEHRKCKQRESLGNVTSEQPAAISAP---------------
-----AACTWDSP----------------------------ARDGCKHRAAAPS-SGA--
--------GT---------------------------------------------ERSVV
EELLRNSLDKAYGKQVLTWEGEVSAVSRDAVRDAEWARSETVIDEWDEEFDRGKVKKVKK
LKRERRRHFNPFQQLQSKRNFWSVTHPAKVASLSYRL

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDLADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGAGRHRSGDEP-QARRQG--SEHAYESGGDG
VPAPQKVLFPTERLSLKWERVYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHT
RNCHQGSFCMLCVMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYLLFYLRIPSSKRSPDGSLSRTVSS-IPGRP-GLVPDHFKKNIGNGTVCSPLIG
KRLDPVTVKKLP-ATEELGVPVSRNGSVSGPKSQNGYVPPK---------PPVGSP----
--SPRLSKTPPHTPTILDEPGKKVKKSSPLQHLSPSRKASQGFHGTSNGSGSR---SEGH
RQGSWDGRGTALSTSPRLPARVTANGHGPKAGGAS---PELDGRD------SCSSSP---
---EHSASSDPANAPQTPKSGAAHLGDSQGTHSSAAGHSRALLNGDDAKAVKPKAPVLSN
A-TTEPASIMSPPPAKKLALSAKKAS-TLRRAAGNDLRP-PLSPLSELTYPRKTTHPVAA
ASWPVHAIRALSP------------APRPSSHLKLPVG-PRS-ASLSSSPRPPGTSDPQS
CS-STPAPPPQVNGDFQAPPHQLP--EASKSPQSLCKKRKRNRRGENQGQSSETCTAVAG
S-----P-TKRR--RK-K-----RKRT-EAVD-VSPLQEGQMQ-QQPWSLER--S--KEA
RAEVPAD--RLEDNGGRQQE------NGQQVGSVTDSHHVSNRKRRRRGA-EGLGAEDRL
QQNPPWHRTFS------------------------------------------------P
LDIVELEATVASPRKKKKKN--RPQESRQE------VEENEHPDTCPSKRQRGS-AIP--
--------GS--PPPP-----AVNGRRPGDRAE---------PAPAPLGPWSRERGCDVL
QELLKYSSDKAYGRKVLTWGGEVSAVSQDAIEDSRWARAATVIDDWDEEFDRGKEKKVKK
FKRERKRTYNAFQKLQSRRNFWAVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGRLLAASAKKVLLQR
IEFEPASKSFSYQLESLKSKYVLLSARAEGASRHRSGDEL-QARKPG--TERVSGSGGDG
VPAPQKVLFPVERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCLMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKSDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVSRVGTT-LSSRP-KVVPEHPKKSPGNGVVPSPLMA
KRQDSVMMRKLP-APEEVGVPVSRNGSLPGLKLQNGCAPAK---------TPAGSP----
--SPRLTPTPTHMPTILDEPGKKVKKSAPPQSLTTSPTTSQGSPGTS-----E---SRSQ
RPGSWASRDTIFSTSPKLLARAITNGHRLKGEGSG---VDLEKGD------SSSSSP---
---EHSASSDPAKAPQTAESRAAHACDSQGTNCPTAGHPKALLNGVDAKMVKLKSPALSS
T-TTEPTSLMSPPPAKKLALSAKKAS-TLRRATGNDIGSPSPSAFCDLTSPMKATHPVVA
STGPVSKTRTAAP------------APRPPTHPH------S-ASLSSSSAKPLGTSEPQS
CRPSAWTPLPQVNGHFTSHLHQLP--EASEALHSPSKKRKKTPNGDPQRLGIDTLLPQCL
RGAPAVARRKRKKRCS------------EGEGATAPKQEGQFQ-DQSWSSGS--------
----------QKEEGTQPQV------NGHQVSHILDSYHVSSRKRRKRKRSEGLSQEATP
SQDLIQHSCSPA------------------------------------------------
-DHSEPEARTELQKKKKKKRRKRKPEPQQ-------DEESKHPGDQRSPRPSVTPVP---
-------------------ALSVNGHLPSNCLGL---------GQAPLVTWNRDQEPDVV
QALLQDSSDKAYGKKVLTWDGEPSAISQDAIKDSRLARTQTVVDDWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKVASLSYRR

------------------------------------------------------------
---------------MPQACTMPIVDKLKEALKPGRKDSAEDGELGKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRPKSGDEP-QAKRQGTGSERLPGSSSDG
VPAPQKVLFPTERLSLRWERIFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATVQCLTYTPPLANYLLSREHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPSSKKSPEGLISRASST-LPSCP-SVVPDHTKKSAGNGVTSSPPAA
KLQGAVPMRKPR-PPEEIGVPVSRNGCVPGPKSQNGYVPAQ---------SPLGSP----
--RPRLAPTPAHMPTLLDENGEKAKRQVPSQHCSPSLRTSQCSPSTS-----E---PGSR
RRSSWDTRDTVPSTSLK-PAEATASGHGLKEEDKN---VGLEKEA------PGRSSL---
---EHSPG-SSPKVPQAPEGGAAQVCDSQGTNCPTVGHSKALPNGSDSKMVKLKSPVLGS
T-AFEPVSLMSPPPAKKLALSAKKAS-TLRRATGNDLRPPPPSPLSDLTYPMTATHSIVA
STWPVSKSRAVSP------------APRSSSCPKSPVSPPSA-SLPSSIPH-----PPQS
CS-SSWRALPQVSGGLMSPSHQLLPLGAREAPQSPSRKRNGSPVGKPQMRCSEACILQLL
GGATAAP-CKKRKRKR-R-----KGPEG---M-AIPQEHLQGPPR---SPES--K--RKG
QAELPAH--PREEEGAQPQL------D-----RILDSQHVSSRKRKRKRA-EGLCKKVGL
LQGPSWHSCAS-T-----------------------------------------------
-DHREPETRSESPRKKKRKK--RKPETLQE------EEENKRPEDPRSTKPSVT-TTL--
--------EL-----------SANSQLAGDHPGL---------GQPPLGLWNRERDSDVV
QELLKYSSDKAYGRQVLTWDGEPSAVSQDAIEDSRLARTQTVIDDWDEEFDRGKEKKMKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDPADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRHRSGDEP-QARRQG--SEHAYESGGDG
VPAPQKVLFPTERLSLKWERVY

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHT
RNCHQGSFCMLCLMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRASNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPDGSLSRTVSS-LPGRP-GVVPDHFKKNIGNGTVGSPLTG
KRLDSGTMRKLP-ATEELGVPISRNSSMSALKSQNGYVPPK---------PLVGSP----
--SPRLSKTPPNTPAILDEPGKKVKKSTPPHHLSPSRQTAQGFHSTSNGSGSR---SESH
RQGSWDGRGAALSTSPRLPAGVTANGHGPKAGGES---PELDRRD------SSSSSP---
---ERSASSDPAKAPQTPKNGAAHLGDSQGTQASAAGHSRALPGGEDDGLVKPKSPVLSS
S-ATEPANIMSPPPAKKLALSAKKAS-TLRRAVGSDLRP-PLSPLSDLTYPRKTTHPVVA
ASWPVCAIRAL------------SPAPRPSSHPKLPVG-PRS-ASLAGSPRPPGTPDPQR
CS-SASAPPPQVNGGVRAPPHQLP--EASTSPQSLCKKRKRNRGGESQGQGSEMGTAAA-
---ACPG-KRR---RR-K-----RKRT-EAVE-ASPLREGQ-RPRQQRTPEH--G--KEA
QTEVPAD--SLEDEGGRQQE------DGRPVGSVTDGHPVSSRKRRRQGA-EGLGAQDCL
RQDPPWRRSCP------------------------------------------------P
LDIVALEATVASPRKKKKKK--RQQEPQQE------VGESKHPEGCRGERQRGS-SLP--
--------G---SPPSPAV--N--GRCPGDGAGQ---------APAPLVSWNRERESDVL
QELLKYSSDTAYGRKVLTWGGEVSAVSQDAIQDSRWARAATVIDAWDEEFDRGKEKKVRK
FKREKKRTYNAFQKLQSRRNFWSVTHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRRKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPSRP-SVVPDHSKKNIGNGIVSSPLTG
KRQDSGTMKKLH-ITEEVGVPISRNGSTLGLKSQNGYVPPK---------LPSGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTARSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSCLQPPFSPHP--TLLSSTPKPPGMSEPRS
CS-SFSTALPQVNEDLVSLPHQLP--EASEPPRSLSEKKKKTFLGELQRLGSETCLPQHI
REATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPGSPTH--K--REG
QAQLPAV--RRQEDGTQPQV------NGQPVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSLM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQRA------VEEDGHLEVLRNTKPRDAAVPE--
---------------SSSHTSSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGKLLATSAKKVLLQR
IEFEPASKSFSYQLESLKSKYVLLNPRAEGTGRHKSGDEL-QARKQGS--ER--ASGGDG
VPAPQKVLFPTEQLSLRWERIFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFSIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGAISRAGSA-LPSRP-SVIPDHTKKSTGNGVASSPLAV
KRQDSMPIRKLQ-APEETGVPVSRNGSLPSLKSQNGYVPTK---------PPLGSP----
--SSRLVLTPTHMPALLDEPGKKAKKLVNLQMMKGLGVKVEVFL----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGATRRKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVVPDHSKKNIGNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGFTLGLKSQNGCVPPK---------LPSGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKVPQTARSGAAHLCDSQETNCSTAGHSKASPSGADSKTVKLRSPVLSS
A-AAAPASTMSPPPAKRLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLCSTPKPPGLSEPRS
CS-SFSTALPQVNEDLVSPPHQLP--EASEPPRSPSEKRKKTFLGELQRLGSETRLPQHI
REATVAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPGSPTH--R--REG
EAQLPAV--RWQEDGTQPQV------NGQQVGCVTDGHHASSRKRRRKGA-EGFGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQQA------VEEDGHLKGLRNAKPQDAAVPK--
---------------SSSHTPSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGKLLAASAKKVLLQR
IEFEPASKSFSFQLESLKSKYVLLNSRAEGTGHHKGRDEL-QARKAG--TERVSGSGGDG
VPAPQKVLFPVERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMLSF--------------------------------
--------------ACKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVCRVGST-LPSRP-SVIPDHPKKSPGNGVVSSPLMA
KRQDSVMMKKLQ-SPEEVGVPVSRNGSVPGLKLQNGCVPAK---------SPAGSP----
--SPRLTPTPIHMPTILDEPGKKVKKPAPPQSLTASPTTSQGSPGTS-----E---CRNQ
RPGSWASRDTIFSTSPKLLAKAFANGHRLKGEGNG---VDLEKGA------SSGSSP---
---EHSASSDPAKVPHSPEGKAAHLCDSQGTDCPTAGHSKALLNGVDPKTAKLKSPALSS
T-TTEPTSLMSPPPAKKLALSAKKAS-TLRRATGNDTRSPPPSALSDLTYPMKATHPVVA
STGPVGQTRAVTP------------APRPSTLLKHSIHPHSA-SLSSSSAKPLGTSEPQS
CRSSAWMPLPQVNGHVVSHLHQLP--EAAEAPHSPSRKRKKTPSGDPQRLGMDTPLPQCL
GGAPAAARRRRRR-----------KECLEDVASTAPQQEGPSQ-DQPWSPRGQ-------
-----------KEEGAHPQV------NGHQVSHVLDSHHVSIRKKRKRKRSEGLSQEVTL
SQNLLQHSCSPA------------------------------------------------
-DHCEPEVRTDLERKKKRRR--RMHEPQQE------EGENKHPEGQGSPRPGVTAA----
------------------PELRVNGHLPSDRLGL---------GQAPLVAWNRDQEPDVV
QELLRDSSDKAYGKKVLTWDGEPSAVSQDAIKDSRSARTQTVLDDWDEEFDRGKEKKIKK
FKKEKKRNFNAFQKLQSRRNFWSVTHPAKVASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGRLLAASAKKVLLQK
IEFEPATKSFSYQLESLKSKYVLLNPKTEGASRHKNSDEP-QARRLG--GEHPHESCTDG
VPAPQKVLFPTERLSLKWERVH

PF00443 // ENSGT00890000139343_3_Domain_1 (203, 1357)

RVGAGLHNLGNTCFLNATVQCLTHTPPLANYLLSKEHA
RSCHQGGFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-----------------------------------------------XXX
XXXXXXXXXXXXXXXCKKKVPASKRFSIHRASSVLTLSLKRFANFSGGKITKXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX-XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXX----
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXX-------X-XXX---
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X-XXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXXXXXXXXXXXXXXXXXXAHTLRRATGTDLRPPPHPPSSDLTRPPKATHPVGA
TTGPARQTRAAPP------------APTPSSHPRPPYSTHSMYPSLPISSQPLRRTGSHS
CS-LASAPWPQVNGAPASPPHQRQ--EAREAPQNTSKKRKKRCVGELRRQGLEPRSPLCG
EDEAVVPHGKKRRMKRKRTAGR----------DVSPL-----QGGPAWAQNQSHRVRNWC
QVEPPTN--RLQE--------------GENRLETTDIHHVGCKKKRKR--AESLQGQEGP
PRDPALHSCSPL------------------------------------------------
-DGAQPEMAVESPRKKRKRQ--RKCESHQE------VDENERQNSQGCDRDSPSL-----
--------------ELSSHLPTVNGRCPGGKRGQ---------TPIPLVSWNSERESNVV
HELLKYSADKAYGRKVLTWDGEISAVSRDAIEDSRLARTERVIDDWDEEFDRGKEKKRKK
CKREKKRTFNAFQKLQSRRNFWSATHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVEKLKDALKTVENDS-EDTELGKLLASSAKKILLQR
IVFHPASSNLCYQLKALKSKYVFLNPHSQTAICNGKTDGI-LTQHQM--VSHTYMGRSDG
VPVPQKILFPADKLSMKWDRIS

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLQNLGNTCFLNATVQCLTYTPPLANYLLSKEHS
RNCQQSGFCMLCIMQNHLIQVFANSGNNVKPVSFIRDLKKIARHFRFGSQEDAHEFLRYT
IDAMQKACLNGYARLDRHSQATSLVHQIFGGYLRSRVTCSVCKNVSDTYDPYLDIALEIR
NVPNIVCALEMFVKSDVLSGENAYMC-A--------------------------------
--------------RCKKKVPACKRFSVHRESNVLTLSLKRFANSSGGKITKEVGYPEFL
NLRPYMSQRNGVPVMYALYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHASNIKV
VLNQQAYVLFYLR-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRRDSAEDGDLGKLLAASAKKVLLQR
IDFEPASKSFSYQLESLKSKYVLLNPRAEGAARHKSGDEL-LAGKPG--PEHTSGSGGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCVLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYI
IDAMQRACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRELAVS--------------LPG----VCADCSQKVP---------RL
IAFYSMPMRKPQ-VPEEVGVPVSRTGSMLGLKSQNGYVPTK---------APVGSP----
--SPRLTPTPTHVPALLDESGKKVKKPVPLQPHPPAPHTSQGWWGMGSHSGL--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRRKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPSRP-SVVPDHSKKNIGNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGSTLGLKSQNGYVPPK---------LPSGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTARSGAAHLCDSQETNCSPAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGMSEPRS
CS-SFSTALPQVNEDLVSLPHQLP--EASEPPRSPSEKKKKTFLGELQRLGSETRLPQHI
REATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPGSPTH--K--REG
QAQLPAV--RRQEDGTQPQV------NGQPVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWHSSCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQRA------VEEDGHLEVLRNAKPRDAAVPK--
---------------SSSHTPSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRLAQTETVVDDWDEEFDRGKEKKVKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRHKSGDDPPPARRQG--SEHMYESCGDG
VPAPQKVLFPTERLSLRWERVFRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVIPDHSKKNIGNGIISSPLTG
KRQDSGTMKKLH-TTEEIGVPISRNGSTLGLKSQNGCVPPK---------LPSGSP----
--SPKLSQAPTHMPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSNSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKGNDES---TGLDRRS------SSSSSP---
---EHSASSNSTKVPQTPRSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPIVA
STWPVHRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGTSEPRS
CS-SISTALPQVNEDLVSLPHQLP--EASEPPRSPSEKRKKTFVGELQRLGSETCLSQHI
REATAAP-HGKRKRKK-KKRLEDTA--------ATALQEGQTQ-RQPGSPRH--R--REG
QAQLPAV--RRQEDGTQPQV------NGQQVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPEAVEESPRKKKKRK--RKQEPQRA------VEEDGHLECPRSAKPRDAAVPE--
---------------SSSRAPSANGWCPGDRMGL---------SQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAVEDSRQARTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRRKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPMERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPSRP-SVVPDHSKKNVSNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGSTLGLKSQNGYVPPK---------LPSGSP----
--SPKFPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDAVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTARSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGMSEAQS
CS-SFSTALPQVNEDLVSLPHQLP--EASEPPRSPSEKKKKTFLGELQRLGSETCLPQHI
REATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPGSPTH--K--REG
QAQLPAV--RRQEDGTQPQV------NGQPVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQRV------VEEDGHLEVLRNAKPRDAAVPE--
---------------SSSHTPSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDSIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADEGELGKLLASSAKKVLLQK
LEFEPASKSFSYQLESLKSKYVLLNPRTEGAGCHRSGDEP-PARRQXXXXXXXXXXXXXX
XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXHQGSF

PF00443 // ENSGT00890000139343_3_Domain_4 (249, 308)

CMLCVMQNHIIQAFANSGNAIKPVSFIRDLRSIARHFRFGNQEDAHEFLQYT
VDAMQKA

ENSGT00890000139343_3_Linker_4_5 (308, 520)

CLNGSNXXXXXXXXXXXXXXXXXXXXXXXXKCLNCKGVSDTFDPYLDITLEIK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------X------XXXXXXX-----
--------------XXX-------XXXXXXXXXXXXXXXXXXXXXX--XXXX----XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00443 // ENSGT00890000139343_3_Domain_5 (520, 551)

ASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
XRPDPVTMKKLQ-TPEEVGVAIARNGSVLGLKSQNGHAPPK---------LPSGSP----
--SPKLSKTPTHTPTLLEEPGKKVKKSATLQPFSPSPKTAQGLHRTGDPSGSR---CASR
GQSPWDSRAAPVSTSARAPAAGPADGPEAGGQGSA-----ADGWA------SGTSSP---
---ESSASSGQARAPRPPGSRATPLRDAHGTDSAAAGPSKTPPXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXAVSP------------APRPSSHLKPHPGPCT--SSLSSSSQPFGTSDPRS
CS-SASAPLPQVNGGIRAPPHQLL--EASEPPQILRKKRKKSPVGETRGLEQHATA----
-----AP-PGKRRRRK-RRQTGDT--------DASSRQEGKVQ-RQPWGPECRG----RA
RVGLPMD--RLEEGSGQQQE------NSQRVGCVTDGHPVSNRKKRRRGA-ESLGGEDCL
PQDPPWL-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRRKSGDGP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVVPDHSKKNIGNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGSTLGLKSQNGYVPPK---------LPSGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTARSGATHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGMSEPRS
CS-SFSTALPQVNEDLVSLPHQLP--EASEPPRSPSEKRKKTFLGELQRLGSETCLPQHI
REATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPGSPTH--K--REG
QAQLPAV--RRQEDGAQPQV------NGQPVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQRA------VEEDGHLEGLRNAKPRDAAVPE--
---------------SSSHTPSVNGWCPGAHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKKEKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGATRRKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVVPDHSKKNIGNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGFTLGLKSQNGCVPPK---------LPLGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKVPQTARSGAAHLCDSQETNCSTAGHSKASPSGADSKTVKLRSPVLSS
A-AAAPASTMSPPPAKRLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLCSTPKPPGLSEPRS
CS-SFSTALPQVNEDLVSPPHQLP--EASEPPRSPSEKRKKTFLGELQRLGSETRLPQHI
REATVAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPGSPTH--R--REG
EAQLPAV--RWQEDGTQPQV------NGQQVGCVTDGHHASSRKRRRKGA-EGFGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQQA------VEEDGHLKGLRNAKPQDAAVPK--
---------------SSSHTPSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGDLGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRHRSADEP-QSRRQG--SEHAYESGGDG
VPAPQKVLFPTERLSLKWERVYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTLQCLTYTPPLASYLLSKEHT
RNCHQGSFCMLCLMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYI
VDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPDGSLPRTVSS-VPGRP-AVVPDHLKKSVGSGSVGSLLTG
KRPDSLPTKKPP-APEEVGVPVSRNGSVLSLKSQNGYVPLK---------PSVGAP----
--SPRLSKTPPPTPTSLDEAGKKVKKPIPLGPLSPSRKASQGFHGTSSGNGSR---SESP
RQGSWDGRAAALSTSPRLPAGGTANGHGPKAGSES---RELHRRG------SCSSSP---
---GRCASSDPTKGPQAPESGATRLGDSQGTQ------SRALPDGDDSKVVKPKSPVLSS
T-AAEAANIMSPPPAKKLALSAKKAS-TLRRAAGSDLRP-PLSPLSDLTYPRKTSHPVAA
ASWPVCAIRALSP------------APRPSSHLKLPVG-PHS-VSLSSSPRPLGTSDPQS
CS-SASAPPPQANGDFQAPPHQLP--EAAKSPHGLCKKRKRNRRGESQGQGSETCTAATA
S-------PGKRKRRK-R-------KRAEALD-ASPLQEGQMR-RQPQSVER--G--KEA
RAEVPTD--RLEDEGGRLQE------NGRQVGSVTDGHPVSSKKRRRKGT-EGLGAGDGL
QRDPPWHRSCSPS-----------------------------------------------
-DVIELEAAVASPRKKKKKK--RQQESWQE------VEENEHPEVCRGERQRDS-ALPGS
-----------------PPSPPLNGRRPGNGAGQ---------ALAPLASWGREPESDVL
QELLEYSSDKAYGRKVLTWGGEVSAVSQDAIRDSRWARTATVIDDWDEEFDRGKEKKVKK
FKREKKRTYNAFQKLQSRRNFWSVTHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSTDDGDLGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTESAGRHKSCDEA-HIRRQG--SDHGFESCSDG
VPAPQKVLFPVERLSLKWERIYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHT
RNCHQGGFCMLCVMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYI
IDAMQKACLNGYTKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPEGPIAKTASA-LPTRTNNVVPEHIKKNISNGIVPSPLIG
KKLDLVSVKKLQ-TAEENGVPVSRNSFVVGLKSQNGSVQLK---------LPLGSL----
--SPKLCSKPIHGPIILDKLGKKVKKPLSLQHLSPSLKMSQGLNGISNLSSTK---LESR
RQSSWESKNAVLATSPKLLPEVTINGHGPKSNGEC---SDPKRKD------SISSSP---
---EYSSSGETARGPETSKSGVGCFYTSQETDYSAGERAKEPPGGEDSKMVKLKSPVLTN
T-ATEPTSIMSPPPAKKLALSSKKAS-TLRRATANDLHSPPHSSFADHTYPTKITHPVFT
SSWPVSKIRAVSPLKSSNTMKSAFNS-----------YSIKA-SPLPSSLRPSGMTEPHS
CS-FASNPLPQVNGDFVSPSHQQQ--GTSSAPYSFSKKRRKKHIGEDRPIRSLEEEISQR
NGKAADL-SHIKKKKK-R-----KHRSWIEVA-ASLIQEEQ---TQSCNSEI--G--TKL
CLDVAVN--GLEEESENQEM------NDSHKGDMTDAHYLSKKKEKKRKRMEECNEEH--
-----WKVVKRHQ----------------TVHLL-------------------SSLNLHS
RFFMESGNRWKKTHQKH------------------------QRKDCQN---DPK-VIP--
--------KE--NTFCKDS--NQSQALNGQHPGN--------KKQAPLQLWNREKESNVV
QELLKYSSDKAYGKKVLTWDGEMSAISQDAIQYSRLAQNETVIDDWDKEFDFGKEKKTKK
FKREKRRNFNAFQKLQSRRNFWSVTHPAKVTSLSYRR

------------------------------------------------------------
---------------------MPTVDKLKEALKPGRKDSTDDGDLGKLLASSAKKVLLQK
VEFEPVSKSFSYQLESLKSKYVLRNPKTESAGRHKSCDEA-HIRRQG--GDHG-LKAGVT
VPAPQKVPFPVERLSLKWERIYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGDACFSNSTIQCLTPPPPLASYLLSKEHT
RNCHRGGFAVGYAESHDPIQAFANSGNAIKPVSFIQDLKTIARHFRFGNQEDAHEFLRYI
IDAMQKACLSGSTKLERQTQATTLVHQSCGGSLRSRVKGSVCKSVSDTYDPSLDVALDIR
QAANRVRALELLVKPDVLSGEHAYTC-A--------------------------------
--------------KCKKKVPASKRFTVHRTSKVLALSLKRFAHFSGGKM------PEFL
NMRPYMSRSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQCYQMNDSLVHSSSIRV
VPSQQAYARFYLRIPGSKKSPEGPIAKTASA-LPTRPNNVAPEHIKKNTSNGAVPSPLIG
KKLDLVSVKKLQ-TAEENGVPVSRNSFVGGLKSQSGRVQLK---------LPLGSL----
--SPKLCSKPVHGPIIVDKLGKKVKKPLSLQHLSPSLKMSRGLNGISNLSSTK---LESR
RQSSWESKNAVLATSPKLLPEVTINGHGPKSNGEC---SDPKRKD------PISSSP---
---EYSSSGETARGPETSKRGVGCFYTSQETDYS---------GGEDSKMAKLKSSVLTN
T-ATEPTSIMSPPPAKKLGLSSKKAS-TLRRVTANDLHSPPHSSFADHTYPTKITHPVST
SSWPVNKIRAVSPLKSSNTMKSAFNSYSI------------KASPLPSSLRPSGMTEPHG
CS-FASNPLPQVNGDFVSPSHQQQ--GTSSAPYSFSKKRRIKHIGEDRPMRSLEEEISQR
NGKAADLSHIKKKKKR-------KHRSWTEVA-VSLVQEEQTE-----------------
----------LEQ-------------RKQKPRDMTDAHYLSKKKEKKRKRMEECNEEHCH
YQKSSLDSSCSLGQGRTR------------------------------------------
-----------------------------E------GEENEHQKHQRKDCQNDPKVIPKE
------------NTFC--MDSNQSQALNGQHPGNVAPYMFLEKKQAPLQLWNREKESNVV
QELLKYSSDKAYGKKVLTRDGEMSAISQDAIQYSRLAQNETVIGDRDKDFDFGKEKKTKK
FKREKRRNFNAFQKLQSRRNFWSVTHPAKVTSLSYGR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDLADDGELGKLLASSAKKVLLQK
IEFQPASKSFSYQLESLKSKYVLLNPKTEGASRHKNGDDP-PARRQG--SEPTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KAGIT------GLSHRTHE-FYL---PF----PCFFKQDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPISKTGSSSLPSRP-SVAPDHSKKNMGHGLVCSPLTG
KRQDSGTTKKLH-TTDEIGVPVSRNGPMAGLKSQNGCVPPK---------LPSGSP----
--SPKLSQTPTHMSTLLDDPGKKVKKPAPPQHSSPSPRTAQGPPATNNSSSSR---SGSQ
RQGSWDSRDGVLSTSPKLLAAAPANGHGLKGNGES---AGLERRG------SSSSSP---
---EHSASSDSSKAPQAPRSGAARLCDSQERNCCTAGHSKTPPSGADPKTAKPKSPVLSS
A-AAEPPSTMSPPPAKKLALSAKKAS-TLWRAIGNDLRPPPPSPSSDLTHPTKTSHPVVA
SAWPVGRARAVSP------------ASHSSSRLHPPFSPHP--TLLSSTPKPPGTSEPRS
GS-SISMALPQVNGDLVSLPHQLP--EASEPPRSPSEKRKKTLVGELQRPGSETCLSQHV
REATASPH-RKRKKKR-RKCPEA--------TAAATLQEGQIQ-RQRGSPTH--G--REG
QALLPAV--RWQEDGTWPQV------NGQQVVCVPDSHHENSRKRRRKGA-EGLGEEGSL
HQDPPWHSCSPT------------------------------------------------
-GDGDPEAMEESPRKKKKKK--RKQEPQRA------VDEDGHLEGPRSAKPRDAAVPE--
---------------SSSHTPTVNGWCPGDCMGL---------GPAPPVSWNGKRESDVV
QELLKYSSDKAYGRKVLTWDGRVSAVSQDAIEESRLARTQTVVDDWDEEFDRGKEKKIKK
YKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSTDDGDLGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKIEGANRHKSCDEA-QIRRQG--SDHGFESCSDG
IPAPQKVLFPMDRLSLKWERVY

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHT
RNCHQGGFCMLCVMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYI
IDAMQKACLNGYTKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSSEGPTAKTVSA-LPSRANNIVPEHIKKKFSNGVVPSPLIG
KKLDLTSVKKQQ-TAEENGVPVSRNSFVVGPKSQNGSVQLK---------LPLGSL----
--SPKLSAKPIHGPIILDKLGKKVKKPLSLQHL--STKSTQGLNGISSLSSTK---LESR
RQGSWENKSAVLATSPKLLPEVTVNGHGPKGNGEC---SDPKRKD------SISSSH---
---EYSASSEIARGPETLKNGVGCFYNSQETDYSAGERTKEPPGGEDSKMVKLKSPVLTN
T-ATEPTSIMSPPPAKKLALSSK-AS-TLRRATGNDLHSPPHSSFADHTYPTKITYPVFA
SSWPVSKIRAVSPPKSSNC---------------LQLLLSQN-FTLPSSFRPSGMTEPHS
CS-FASNPLPQVNGDIKSPSHQQH--GASSAPQSFSKKRRKKHIEENRPYQNPEEEISQG
NEEAAEL-SHVKKKKK-K-----RKDM-EDRS-CCILQEEQ---IQTPTGRD--R--KEV
WVKVTVD--GLEEESKNQEM------NGSHITDVTNAHYLSRRKRRKKGT-EECNEEHCH
YQKSSLDSY-------------------------------SIC-----------------
-DKDEPESITESPRKKKKKK--RKQNSEQD------VEENKHQKHQRTAKPQDH-TV---
---------------CKES--NQSQAVNGQHPGK---------KQAPLHLWNK--ESNIV
QELLEYSSDKAYGKKVLTWDGEVSAISQDAIQYRRMAQNETVIDDWDKEFDSGKEKKTKK
FKREKRRNFNAFQKLQSRRNFWSVTHPAKVTSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGRLLAASAKKVLLQR
IEFEPASKSFSYQLESLKSKYVLLSARAEGASRHRSGDEL-QARKPG--TERVSGSGGDG
VPAPQKVLFPVERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGGFCMLCLMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKSDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVSRVGAT-LPSRP-KVVPEHSKKSPGNGVVPSPLMA
KRQDSVMMRKLP-APEEVGVPVSRNGSLPGLKLQNGCAPAK---------TPAGSP----
--SPRLTPTPTHMPTILDEPGKKVKKSAPLQSLTTSPTTSQGSPGTG-----E---SRSQ
RPGSWASRDTIFSTSPKLLARAITNGHRLKGEGSG---VDLEKGD------SSSSSP---
---EHSASSDPAKAPQTAESRAAHACDSQGTNCPTAGHPKALLNGVDAKMVKLKSPALSS
T-TTEPTSLMSPPPAKKLALSAKKAS-TLRRATGNDIGSPSPSAFCDLTSPMKATHPVVA
STGPVSKTRTAAP------------APRPSTHPH------S-ASLSSSSAKPLGTSEPQS
CRPSAWTPLPQVNGHFTSHLHQLP--EASEALHSPSKKRKKTPNGDPQRLGIDTLLPQCL
RGAPAAARRKRKKRCS------------EGEGATAPKQEGQFQ-DQSWSSGS--------
----------QKEEGTQPQV------NGHQVSHILDSYHVSSRKRRKRKRSEGLSQEATP
SQDLIQHSCSPV------------------------------------------------
-DHSEPEARTELQKKKKKKRRKRKPEPQQ-------DEESKHPGDQRSPRPSVTPVP---
-------------------ALSVNGHLPSDCLGL---------GQAPLVTWNRDQEPDVV
QALLQDSSDKAYGKKVLTWDGEPSAISQDAIKDSRLARTQTVVDDWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKVASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAKDGELRKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASHPKSGDEP-QAKRQG--SERLSGSSNDG
VPAPQKVLFPTEHLSLRWERIFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATVQCLTYTPPLANYLLSREHS
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPSSKKSPEGPISRGGST-LPSHP-SMIPDHTKKNAGNGVTSSPPAA
KPQGAVPMRKPQ-TPEEMGVPVSRNGSMPGPKLQNGCVPAR---------SPLGSP----
--PLRLSHTPTPMPTLLDENGKKVKKQVPLQLWLPRGG----------------------
GGGVWPGLVLLPAVGGVS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVIPDHSKKNIGNGIISSPLTG
KRQDSGTMKKPH-TTEEIGVPISRNGSTLGLKSQNGCIPPK---------LPSGSP----
--SPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSNSNSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKGNDES---AGLDRRG------SSSSSP---
---EHSASSDSTKAPQTPRSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
T-TTEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVHRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGTSEPRS
CS-SISTALPQVNEDLVSLPHQLP--EASEPPQSPSEKRKKTFVGEPQRLGSETRLPQHI
REATAAP-HGKRKRKK-KKRPEDTA--------ASALQEGQTQ-RQPGSPMY--R--REG
QAQLPAV--RRQEDGTQPQV------NGQQVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPLRH-SCSPM-----------------------------------------------
-GDGDPEAMEESPRKKKKKK--RKQETQRA------VEEDGHLKCPRSAKPQDAVVPE--
---------------SSSCAPSANGWCPGDRMGL---------SQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRQARTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGKLLAASAKKVLLQR
IEFEPASKSFSFQLESLKSKYVLLNSRAEGASHHKSRDEL-QARKPG--TERVSGSGGDG
VPAPQKVLFPMERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMLSF--------------------------------
--------------ACKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVCRVGST-LPSRP-SVIPDHSKKNPGNGVVSSPLMA
KRQDSVMR-RLQ-SPEEVGAPVSRNGSMPGLKLQNGCVPAK---------APAGSP----
--SPRLTPTPTHMPTILDEPGKKVKKPAPPQSLTTPPTTSQGSPGTS-----E---SRNQ
RPGSWASRDTIFSTSPKLLAKAFANGPRLTGEGNG---VGLEKGA------SSGLSP---
---EHPASRGPAKAPQTTEGRAAHFCDSQGTDCPTAGPSKALLNGVDPKIVKLKSPALSS
T-ATEPTSLMSPPPAKKLALSAKKAS-TLWRATGNDIRSPPPSAFSDLTYPMKATHPVVA
STGPVSKTRAVTP------------APRPSTLLKHSIHPHSA-SLSSSSAKPLGTSEPQS
CRSSASMPLPQVNGHVVSHLHQPP--EAIKALHSPSRKRKKTPNGDSQRLGIDTHLPQCL
EGAPAAA-RRKRKKKK---------KCLEDVAHTAPQQEGPS-QDQPSSPRG--R--K--
------------EEGTHPQV------NGHQVSHILDSHHVSSKKRRKRKRSEGLSQEATL
TQNILQHGCSPA------------------------------------------------
-DHYETEVRTDLQRKKKRRK--RKHESQQE------EEENEHPEGQRSPRPSVTSS----
------------------PELRVNGHLSSDRLGL---------GQAPLVAWNRDQEPDVV
QELLQDSSDKAYGKKVLTWDGEPSAVSQDAIKDSRLARTQTVLDDWDEEFDRGKEKKIKK
FKREKKRNVNAFQKLQSRRNFWSVTHPAKVASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDVELGKLLAASAKKILLQR
IEFEPASKSFSYQLESLKSKYILLNPKTENPSRHKGSEEG-SNRKQGI--EH--VLGGDG
VPAPQKVLFPVERLSLKWERVYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTLQCLTYTPPLANYLLSKEHS
RSCHQGGFCMMCIMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGSQEDAHEFLRYT
IDAMQKACLNGYTKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPFLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRASNVLTISLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPSTRKNPEGPISKSSVS----NRTNIVSDHMKKSMTNGSLSSPQMN
KKQDAAQVKKVSSDTEEAGVPISRSSFTTHSKLQNGTFSSPSHSPLPKFIPSIGFS----
--SPKLPSK----PAFLEDLSKRSKKQSVLP-----LKTSQDFNE---NGSAR---VDMG
KQNSWGDKRLSSSSSHLA--GPPRGDPEAKMRDGS---TELPSKDSSSLTSSLSPSPSSS
SSSSSSPAHNSLKGLPQSTVGINGYCSSQETDCASGKH-----GSEDSKFAKLKSPLLAN
VNNLELGSTMSPPPAKKLALSARKGSNTLQKVSGSEHRAPPHSPPAA----TNTIHPVCA
AALGCP--RVLSPTSKSSTPLQLADS--------------------TSVDVAPSSSFKPR
CL-SAAAPLSPPAVPTQAPSHSHPDKGPF-LDRSRKMKRKHSAPGEEQDNHFS-SNVTNF
NAEGTQLLSPPRKKRQ-L---KEN----GSVL-SSSVRK---------------------
-SDVAAA--KKEKEGETY-L------D------ARTPNSVRKKKKRLH-----QKEEDCM
PLLSPVNSC-SSQREGEVSG----------------------------------------
-----EESCVK-KKKKKKKK--KKQNLSTDSDKGSYAEESEHRKHKKRESQGDPVPVMSS
PQEKRHGNGISSARLSPSVALACSSQLR--HEDN-CSLNILS--PKKEVIQHKHGQSDVL
QELLKDSLDKAYGKRVLTWEGEVSAVSQDAMQDTAWSRSQTVMDDWDEEFDSGKVKKIKK
LKRERRKNFNAFQKLQSRRNFWAETHPAKLASLSYRL

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDP-PARRQG--SEHTCESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVIPDHSKKNIGNGIISSPLTG
KRQDSGMMKKPH-ITEEIGVPISRNGSTLGLKSQNGCIPPK---------LPSGSP----
--SPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSP--RTAQELPGTSNSNSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKGNDES---AGLDRRG------SSSSSP---
---EHSASSDSTKAPQTPRSGAAHLCGSQETNCSTAGPSKTPPSGADSKMVKLKSPVLSN
T-TTEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVHRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGTSEPRS
CS-SISTALPQVNEDLVSLPHQLP--EASEPPRSPSEKRKKTFVGELQRLGSETRLPQHI
REATAAP-HGKRKRKK-KKRPEDTA--------ASALQEGQTQ-RQPGSPTH--R--REG
QAQLPAV--RRQEDGTQPQV------NGQQVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPEAMEESPRKKKKKK--ESRSHSG-------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGAGRHRSGDEP-QARRQG--SEHAYESCGDG
VPAPQKVLFPTERLSLNWERVYRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTVQCLTYTPPLANYLLSKEHA
RNCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NLRPYMSQSSGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSSVRSSNIKV
VLNQQAYVLFYMQIPGSKKSPDGSLPRTASS-APGRA-GVVADRFRKNVGNGTLCSPLTG
KRLDPATLKKLQ-ATEELGVLVSRNGSVLGLKSQNGYVPPK---------PPLGSP----
--SPRLSKTPPNTPTILDEPGKKVKKPTPLHFVSPSRRASQGLHGTGTGSGGR---GEGH
RPGSWDGRAAAPSTSPRLPAGVTASGPAAGSER-----PEPDRRG------SGGPSP---
---EHSASSDPTKAPPTPESGAAPSGDSQGTN------PRALPGGEDSKAAKPKPPVLST
T-ATEPASIMSPPPAKKLALSAKKAS-TLRRAAGNDLRP-PLSPLSDLTYPRKTTHPVAA
SAWPVGAIRALSP------------APRPSSRPKLPVGPC---SSLSSSPQPLGTSDPQS
CS-SASAPLPQVNGGFRAPPHQLP--EASKPPRSLCKKRKRNRRGETQGRGSETCALAA-
-----AP-PGKRRKKK-GKR--------AEAVDASPLQEGQVQ-RQHRGLER--R--KEG
RAEVPVD--RLEEEGGRQQE------NGQQAGC-----HVSGRKRRREGA-EGLGAEDGL
PQDPPWHSCSLL------------------------------------------------
-DVTESEASAASPRKKKKKR--RQQESRQE------VQENELPEACRGETQRGPAVPG--
----------------SQPSPAVNGRRPGDRAGQ---------ARAPRVSWVRDGEADVL
QELLEYSSDKAYGRKVLTWDGEVSAVSQDAIQDSRWARAATVIDDWDEEFDRGKEKKVKK
FKKEKKRTFNAFQKLQSRRNFWSVTHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRHRSGDEP-QARRQG--GEHGSEGCGDG
VPAPQKVLFPMERLSLKWERVYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTVQCLTYTPPLANYLLSREHA
RSCHQGGFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSSVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGEPVVYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGFKKSPEGSISRTVSS-LPSRP-GAVPDHVRKNVGNGTVSSPLTG
KRLDPAAMKKLQ-SVEELGVPVSRNGSVSGPKSQNGYTPPK---------PPSGSP----
--SPRLSKTPTHLPTILDEPGKKAKKSAPLQHFSPSPRTSQGFHGTSDSSGGR---SESH
RQATWDGRSAVLPTSPKLPAGVTANGHGPKGGDES---PDPERRD------SSSSSP---
---EHSASSGPAKTPQTPRSAAAHFCDSQGTNSSAAGPSKVLLDGEGAKVVKPKSPVLNS
T-ASEPASTMSPPPAKKLALSAKKAS-TLRRATGNDLHPPALSPSSDLTYPRKTTHPVVA
STWPVGTIRAISP------------APRSSSHPKPPPG-PRR-ASVSSSPQPLRTSDPPS
CS-PTSAPLPQVNGSFRSPPHQLP--EASEAPHSLCKKRKKNPVGETQGPGSVTREAA--
----AAP-PGKRRRKK-RKRTE-------DGD-ACSPQEGKTQ-RQHGGPGH--R--QEG
RAERPGH--RLE-EGGQQQLNGQRLVNGWRVSFVTDGHRVSTRKRRKKGA-EGQGSEDHL
HQDPPWHSCSPS------------------------------------------------
-DIVEPETPAASPRKKKRKN--RKQESRQE------VEENEHPTDPGVERLGGSAVL---
---------------GSGPSPAVNGLRPGDRTGL---------GQAPLVSWNRERESDVV
QELLKYSSDKAYGRKVLQWDGGVSAVSQDAIEDSRLARAATVIDDWDEEFDRGKEKKVKK
LKREKKRNFNAFQRLQSRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDVELGKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPRTEGASRPKSGDEP-QAKRQG--SERFFGSNSDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATVQCLTYTPPLANYLLSREHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPEGPISRASSV-LPSRQ-SVVPDHTKKSAGNGITSSPTTT
KVLLRTMGWREC-S----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGRLLAASAKKVLLQR
IEFEPASKSFSYQLEALKSKYVLLNARAEGASRHRSGDEL-QARKPG--IERVSGSGGDG
VPAPQKVLFPVERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCLMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKSDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVSRVGAT-LPSRP-KVVPEHPKKSPGNGVVPSPLMA
KRQDSVMMRKLS-APEEVGVPVSRNGSLPGLKLQNGYAPAK---------TPAGSP----
--SPRLTPTPTHMPTILDEPGKKVKKSAPPQSLTTSPTTSQGSPGTS-----E---SRSQ
RPGSWASRDTIFSTSPKLLARAITNGHRLKGEGSG---VDLEKGD------SSSSSP---
---EHSASSDAAKAPQTTESRAAHACDSQGTNCPTAGHPKALLNGVDAKMVKLKSLALSS
T-TTEPTSLMSPPPAKKLALSAKKAS-TLRRATGNDIGSPSPSAFCDLTSPMKATHPVVA
STGPVSKTRTAAP------------APRPSTHPH------S-ASLSSSSAKPLGTSEPQS
CRPSAWTPLPQVNGHFTSHLHQLP--EASEALHSPSKKRKKTPNGDPQRLGIDTLLPQCL
RGAPAATRRKRKKRCS------------EGEGATAPKQEGQCQ-DQSWSSGG--------
----------QKEEGTQPQV------NGHQVSHILDSYHVSSRKRRKRKRSEGLSQEATP
SQDLIQHSCSPE------------------------------------------------
-DHSGPEARTELQKKK-KKRRKRKPEPQQ-------DEESKHPGDQRSPRPSVTPVP---
-------------------ALSVNGHLPSDCLGL---------GQAPLVTWNRDQEPDVV
QALLQDSSDKAYGKKVLTWDGEPSAISQDAIKDSRLARTQTVVDDWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKVASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALRPGRKDSADD-ELGKLLASSAKKVLLQK
IEFQPASKSFSYQLESLKSKYVLLNPKTEGASRHKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTDRLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NMRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPISKTGSSSLPSRP-SVSPDHSKKNLGNGLVCSPLTG
KRQDSGTMKKLH-TTDEIGVPVSRSGPMVGLKSQNGYVLPK---------LSSGSP----
--SPKLSQTPTHMPTLLDDPGKKVKKPAPPQPSSPSPRTAQGPPATSNSSSSR---SGIQ
SQGSWDSRDGVLSTSPKLRAAATANGHGLKGNDES---AGLERRG------SSSSSP---
---EHSVSSDSSKVPQASRSGAARLCDSQERNCCTAGHSKMPPNGVDPKTVKLKSPVLSS
A-AAEPPSTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
SAWPVGRARAVSP------------APQSSSCLQPPFS-PHP-TLLSSTPKPPGTSEPRS
GS-SISTALPQVNGDLVSLPHQLP--EASEPPWSPSEKRKKTLVGEFQRPGSETCLSQHI
KEATASS-HRKRKRKK-RKHP-------EDTA-ATTLQEGQTH-RQSGSPTH--R--REG
QAQLPAV--RWQEDGTRPQV------DHQQVACVPDSHHPSSRKRRRKGA-EGLGEEGGL
HQDPPWHSCSRMG-----------------------------------------------
--DGDPEAMEESPRKKKKKK--RKQEPQQA------VEEDRHCEDPRSAKSQDV-AVP--
--------------ESSSHAPSVNGWCPGDHMGL---------DPAPPVSWNGEQESDVV
QELLKYSSDKAYGRKVLTWDGKVSAVSQDAIEESRLARTHTVIDNWDEEFDRGKEKKIKK
YKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---HQ

PF00443 // ENSGT00890000139343_3_Domain_3 (246, 551)

GGFCMMCVMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGSQEDAHEFLRYT
IDAMQKACLSGCTRLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVSLEIR
QAANIVRALELFVKSDVLSGENAYMC-A--------------------------------
--------------RCKKKVPASKRFTIHRASNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNTGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHCSNIKV
VLNQQAYVLFYLRIPGPRKGSEGPIAKA----SPSHS-PVVSDQTKRTATNGPPAVTASG
PGEAEGGRGKLS-GPEEIGVPVARSSLGAGPKLSNGSAPPK---------PPTGSP----
--SPKLPLRATQVTPSDDT-ARRPKK-TPSLQQPPAPKASPGPC----GSSTA----DPP
QQSPGDSMQSPTSPSPGTP--------------------QRSSCS------SAAPSP---
---AHTAAGDAAKATPKAKSGAGSLDPSQDTDCG-----ADLPEG-------SRLTKLKS
A-ALEPGSTTSPPPAKKLALSAKKGS-TPRRASGSDGRV-QPAG---LAFATAT-----A
QPWPCSRPSLFQPLFLSCRLPSALPLPSPDT-PAFSFT-PSA-A-----PQLPA------
--------SPLTNGAHPSQHHPTL--SGEHGPSPMSTKKKQRKQQQSKAGGSSHVMAVNG
CNEGCSP-PRK---RR-N-----IAPE-GSI----PGKEAAGTG--------------S-
--MEPI----------------------SPLKKKKRKRRLQETEERSSGA-QPLGR----
--------QQQSPEPSEGESEHRKCKQRESLGNVTSEQPAAICAPGGGDVGHPSCLSSPA
FPIAAAACTWDSL----------------------------ARHGCKHGAAAPS-TGV--
--------GT--QPPQPGA--QRSGGAAQKFLGX---------PSTGVGTQPHSPERSVV
EELLRNSLDKAYGKQVLTWEGEVSAVSRDAMRDAAWARSETVIDEWDKEFDRGKVKKVKK
LKRERRRHFNPFQQLQSKRNFWSVTHPAKVASLSYRL

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRRDSADDGELGKLLASSARKVLLQK
LEFEPASKSFSYQLESLKSKYVLLNPRTEGAGCHRSGDEP-QARTQG--SERAYESCGDG
VPAPQKVLFPVERLSLRWGRVY

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLHNLGNTCFLNSTVQCLTYTPPLANYLLSKEHT
RGCHQGSFCMLCVMQSHIIQAFANSGNAIKPVSFIRDQXXXXXXXXXXXXXXXXX-XXXX
XXXXXXXXXXXXXXLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMCA---------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSNGEPVMYGLYAVLVHSGYSCHAGHYYWYVKASNGQWYQMNDSFVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPEGSICRTASS-LPSHP-RVVPDHSRKNISNGTTSSSVTG
KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX---------XXX------X
XXXXXXXXXXXXXXXXXXEPGKKVK-PAPLQHFSPPLKTSPGPSGAGELCCSW---CEDR
RPGSWDGRAT-LSTSPRPPAARTTNGLPKVGDEGP----AAERSA---------------
SSLEHLAGGGPARPPPAPQSGAAPPGDSQGTHS--AGPAKVLPAREDAELVKAKCPDLSS
A-SPEPANTMSPPPAKKLALSARKAS-TLRRATGNDLRPPPLSPSSDLTSPRKPTHPVVA
STWPVSTIRAVSP------------APRPSSHLKPPPGPHS--PSLSSSPPPLGTSDPQS
HS-PASAPLPQVNGGFRAPSHQLP--EAIEPPQGLCKKRKKTRVGETQGQGSELHSWA--
----APPGPPRKRRKRKRKHTGDT--------DASPLQAGRMP-GPPWSPAH--R--KEG
RAEPLAG--RPEEEGGQQPG------NGWPVGCVSDGHRVSRRKRRRQGA-EGLGGEDGL
RRDHPPRRGCSSS-----------------------------------------------
-DVVQPEAIAASPRKKRKKK--RKQESQQE------VEENEPRAR-------GSEVP---
---------------GSRPGTAVNGQAPGGPTGL---------GQAPLVSWDRERESDVV
QELLKYSSDKAYGRRVLTWDGEVSAVSQDAIQDSRLARMATVIDDWDEEFDRGKEKKLKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKASSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDAELGKLLASSAKKVLLQK
IEFEPASKSFSYQLEALKSKYVLLNPKSEGAGRHKTWEDA-PVRRQGSDHGLGSSSGGDG
VPAPQKVLFPTERLSLRWERVYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHS
RSCAPGGFCMLCVMQNHMIQTFANSGNAIKPFSFIRDLKKIARHFRFGSQEDAHEFLRYT
IDAMQKACLNGHAKLDRQTQATTLVHQIFGGYLRSRVKCSLCKSVSDTYDPYLDVALEIR
QTANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFSIHRASNVLTLSLKRFANFCGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSSVHSSNIKV
VLNQQAYVLFYLRIPGFKKSPEGPISKAPPT-PANRTNSIGPDHVKKIISNGALSSPLIG
KRQDGGPRKKPQ-VTEETGVVVPRSSVTAGPRPQNGTPQSK---------LPPRCP----
--SPKPSAK--PSPTSPEEPGKKVKKPVPLQRFP------AGPNGTGEPCGSK---PQSR
RPGSWEGREAAPASSPRLPEATAVNGHGPKGAGGSGGGSDPDGGD------SSSSSPE--
---RSSGSDAGARGPPTPRGGAARFRPPRETDPPAGERTEEPPGGGDPKGAKSPSSPPTN
TAAVEPANAMSPPPAKKLALSARKAS-TLRRATSNDLRPPPHPSIADHTYPTKTTHLVFA
SPWPVSKARADSPPKSSLSLPSKFTF---------------------CSPPALKASTRPS
CCSPASAPQPQVNGDPGSPPPQRQ-QGASPAPPSFSGKKRNRHSGETESQSGPEAESSPG
NGQGTEPRQGKKRRRR-RRHGEDGHRRPAAG-----------PESLAWEDRA--G--RGD
GSRGARREAEPESRDENQE------PGGSQVGDRTDAHRHRRRKKRKEEEQEEEEEQE-T
TDEASHHQSRKKKK-----KKKRKQEEQEESGD-PSQQPNS------------------D
SSSVQAETPAEAPKKNKKRK--R--DSEQE------AEESEPRPT---------------
----------------PSGALCEDGDPLGTADGLRPRVNGLGKEKVPQSPAEEQNTSSVL
QELLRYSSDRAYGKQVLTWSGEISAVSQDAIQDSRLARSEMVIDDWDEEFDRGKVKKFRK
FKPEKKRNFNAFQKLQSRRNFWSATHPAKASSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGKLLAASAKKVLLQR
IEFEPASKSFSYQLESLKSKYVLLNPKAEGAGRHRSGDEP-QARKPG--TERMSGSGGDG
VPAPQKVLFPVERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCRSVSDTYDPYLDIALEIR
QAANIVRALELFVKSDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFSIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLSQQAYVLFYLRIPGSKKSPEGPVSRVGAT-LPSRP-KVIPEHPKKSPGNGVVSSPLMA
KRQDSLMMRKLQ-SPEEVGMPVSRNGSISGLKLQNGCAPAK---------SPAGSP----
--SPRLAPTPTHMPTILDEPGEKVKKSAPPQSRTTSPTASQGFPGTG-----E---SRSQ
RPGSWASRDSIFSTSPKL-AKAITNGHRLKGEGNG---VDLEKGD------SSSSSP---
---EHSASSDAAKAPQTSEGRAAHVCDSQGTNCPATGHSKVLSNGVDAKMGKLKSPALSS
T-TTEPTSLMSPPPAKKLALSAKKAS-TLRRATGNDIGSPSPSAFCDLTSPMKATHPVVA
SPGPVSKTRAAAA-----------PAPQPSPH------PHSA-SLSSSSAKPLGTSEPQS
CCSSAWTPLPQVNGHFTSHLHQLP--EANEALHSPSRKRKKTPSGDPQRLGRDTHLPQCL
EGAPATARRKKRKKKK----------DLEGVGDTATQQESQS-QDQPWSPRG--R--K--
------------EEGTQLQV------NGHQVSHILDSYHASSRKRRKRKRSEGLSQEATV
CQDLLQHGCSPAD-----------------------------------------------
------------------------------------------------------------
----------------------------------------HWLGRAPLVTWNRDQEPDVV
QELLQDSSDTAYGKKVLTWDGEPSAISQDAMKDSRLARTQTVVDDWDEEFDRGKKKGENS
AP-----------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDLADDGELGKLLAASAKKVLLQK
IEFEPASKGFSYQLDSLKSKYVLLNPKTEGASRRRSADEP-QARRQGTCSEHASASCGDG
VPAPQKVLFPVDRLSLKWERVYRVG

PF00443 // ENSGT00890000139343_3_Domain_3 (206, 551)

AGLHNLGNTCFLNSTVQCLTYTPPLASYLLSKEHT
RHCHQGSFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QTANIVRALELFVKADGLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRASNVLTLSLKRFANFSGGKITKEVGYPEFL
NIRPYMSQSSGDAVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDALVHASNVKV
VLNQQAYVLFYLRIPGSKKGPEGALSRTVST-LPSRP-GGAPDHFKKHISNGVASSPPTG
KRQDPVTMRRLH-STEEIGVPISRNG----LKPQNENLPPK---------PASGFP----
--SPRVSKTPTHTPTVLDEPGRRVKKSVPAQHPSPPLGTPQGLHGASDAGSSR---AESR
RQGSWDSGGAVLPTSPKLLAEATANGHGPKGNAGG---PDLQRKD------PRSPSP---
---QRSTSGVPTKSPQTPKGGAACFCHSQETNCAAGGHPKALPNGEEATAARPKAPVLSN
P-ATEPTNTTSPPPAKRLALSAKKAS-TPWRATGSDLRSPPHPPFSDLTYPMKSTHPVVA
STWPVSKTRAASP------------APLPCGRLKPPPAPHPTAPPSPSSALPLGASEAQS
SS-FASPPRPQGSGAFVSLPRQPP--GASTAPPSISRKRKRNRGGEVEGRSLEKRLSPP-
-------AARVK-KRKKRRRAEDGGASLLVGE-QTRGPSRSLESGTPWRPGD--------
-------------EASQLRQ---------------NGQHRS--DRRRGRQAEGPNGEDCP
PQDPARPSCSPR------------------------------------------------
-GEVEPEMAAGSPRKKKKKK--RKPESPQE------VEENEHRQGQGSAGRDAAAVP---
---------------TPHGAPSLNGQQPGDRGGL-----FPGKGRVPLVSWNRERGSDVL
QELLKDSADRAYGRKVLTWDGEVSAVSQDAIQDSRLARTQTVIDGWDEEFDQGKEKKIRK
LKREKKRNINAFQKLQSRRNFWSVTHPAKVTSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGKLLAASAKKVLLQR
IEFEPASKSFSYQLESLKSKYVLLNSRAEGASRHKSGDEL-QARKPG--SERVSGSGGDG
VPAPQKVLFPMERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVSRVAST-LPSRP-SVIPDHPKKSPGNGVVSSPLMA
KRQDSVPMRKLQ-TPEEIGVPVSRNGSVPGLKLQNGCVPAK---------APAGSP----
---SRLTPTPTNMPTILDEPGKKAKKSAPPQSLTASPTTSQGSPGTS-----E---SRSQ
RPGSWSSRDTIFSTSPKLLAKAFANGHRLKGEGNG---VDLEKGA------SSGSSP---
---EHSASSDPVKAPQTPESRAAHFCDSQETDSPTAGHSKALLNGVDSKIVKQKSPALSG
T-ATEPTSLMSPPPAKKLALSAKKAS-TLRRATGNDIRSPPPSAFSDLTYPMKATHPVVA
STRPVSKARAVAP------------APQPSTLLKHSIHPHSA-SLSSSSAKPLGTSEPQS
CRASAWMPPPQVNGHFMSHLHQLP--EASEAPHSPSRKRKKTPNGDPQRLGIDTHLPQCL
GGAPAAA-RRKRKKKK-K-------CLEEEAA-TAPQQEGQSQ-DQPWSPRG--R--K--
------------EEGTHPQV------NGHQVNHVLDSHHVRSKKRRKRKRSEGLSQEATL
SQNLLQHGCSP-------------------------------------------------
ADHCEPEARTELQRKKKRRK--RKRESQQE------EEESKHPEGQRSPRPTRPVVPL--
---------------------QT-------CGRLFMCLLITGLGQAPLMTWNRDREPDVV
QELLQDSSDKAYGKKVLTWDGEPSAVSQDAIKDSRLARTQTILDDWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQSKRNFWSVTHPAKVASLGYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGKLLAASAKKVLLQR
IEFEPASKSFSYQLESLKSKYVLLNSRADGASRHKSGDEL-QPRKPG--TERVSGSGGDG
VPAPQKVLFPMERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVSRVGST-LPSRP-SVIPDHPKKSPGNGVVSSPLMA
KRQDSVMMKKPQ-APEEVGVPVSRNGSLPALKLQNGCVPAK---------TSAGSP----
--SPRLTPTPTHMPTILDEPGKKVKKSAPPQSLTASPTTSQGSPGPS-----E---SRSQ
RPGSWASRDTIFSTSPKFLVKAFANGHRLKGEGSG---VDLEKGA------SSSSSP---
---EHSASSDPTKAPQTVEGRATHFCDSQGTDCPTTGHSKALLNGADPKIVKLKSPALSS
T-ASEPTSLMSPPPAKKLALSAKKAS-TLRRATGNDICSPPPSAFSDLTYPMKATHPVVA
SSGPVSKTRAVAP------------APRPSTLPKHSIHPHSA-SLSSSSAKPLGTSEPQS
CRSSAWMPLPQVNGHFMSHLHQLP--EAVEAPHSPSRKRKKTPNGDPQRLGIDTHLPQCL
GGAPAAV-RKKRKKKK-Y--------VEDMAT-MAPQQKGQSQ-----------------
---------DQKEEGTQPQV------NDHQVSHILDSHHVSSRKRRKRKRSERLSQEAIL
SQSLLQHGCCPA------------------------------------------------
-DHCEPEARTELQRKKKRRK--RTHASQQE------EEESQHPEGQRSPRPSVT-PVP--
-------------------ELSVNGHLCSDRLGL---------GQAPLVGWNRDQEPDVV
QALLQDSSDKAYGKKVLTWDGEPSAVSQDAIKDSRLARTQTVLDDWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKVASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYLLLNPKTEGASRPRSGDEA-QARRQG--SER--PCGSDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTAPLANYLLSKEHA
RNCHHGSFCMLCIMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCAVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGDNAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANSSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYLLFYLRIPCSKKSPESPISKAGST-LPSRP-SVVLDHTKKNMGNGVATSPSMA
KRPDPVLVRKLQ-VPEEIGVPVSRNGSVPALKSQNGCVPAK---------LPLGSP----
--SPRLSQTPPHTPTLLEEPGKKVKKPTPPQHFSPSLRTPQGSPGTS-----E---SGSH
RQGSWASRDTVPSTSPKLLASATANGHGLKEEDGS---TDLEKGA------SSSSSP---
---EHSASSEPAKAPQDRGGTAVRICASQETDCPS-GPSRAPPSEADPAVVKLKSPALGS
A-TTEPANLMSPPPAKRLALSARKAS-TLRRATGNDLHSPPPSPFSDLTSPMEAAHPVVA
STWAVSRTRAVSP------------IPRSSSHPKPPVSPPST-SLTSSSPQSPGTSEPQS
RS-SSWTALPQVNGDFTSLSHQP-SLEASKAPQSPSRKKKKLLTGEPQKLGSVARQPQCL
RGEAVAP-RRKRKRKK-RKCPEDP-------G-TIAPQEGQTR-GQPWSPKS--R--KKH
QAELAAD--PQEEEGTRPQA------------NVLEAHHPSSRKRRRRGV-EGFG-RVEL
PQDPPWPSCSSP------------------------------------------------
-DPREPAARMESPRKKKRRK--RKREAQRE------EEENNHPEGPKRLRPSVSAVP---
-------------------VWSMNGQVPGDRLGP---------GQAPLVPWNREREPDVV
QELLRYSSDKAYGSKVLSWSGEPSAISQDAIEDSRLARTQTVLDHWDEEFDRGKEKKMKR
LKREKKRNFNAFQKLQSRRNFWSVTHPAKATSLSHRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDGDLGRLLAASAKKVLLQR
IEFEPASKSFSYQLESLKSKYVLLNARAEGASRHRSGDEL-QARKPG--IERVSGSGGDG
VPAPQKVLFPVERLSLRWERIFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCLMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKSDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQSSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPVSRVGAT-LPSRP-KVVPEHPKKSPGNGVVPSPLTA
KRQDSVMMRKLP-APEVVGVPVSRNGSIPGLKLQNGCAPAK---------TPAGSP----
--SPRLTPTPTHMPTILDEPGKKVKKSAPPQSLTTS-------PGTD-----E---SRSQ
RPGSWASRDTIFSTSPKLLARAITNGHRLKGEGSG---VDPEKGD------SSSSSP---
---EHSASSDPAKAPQTAESRAAHACDSQGTNCPTAGHPKALLNGVDAKMVKLKSPALSS
T-TTEPTSLMSPPPAKRLALSAKKAS-TLRRATGNDIGSPSPSAFCDLTSPMKATHPVVA
STGPVSETRAAAP------------APRPSTHPH------S-ASLSSSSAKPLGTSEPQS
CHPSAWTPLPQVNGHFTSHLHQLP--EASEALHSPSKKRKKTPNGDPQRLGIDTLLPQCL
RGAPAAARRKRKKRCS------------ESEGATAPKQEGQCQ-DQSWCSGG--------
----------QKEEGTQPQV------NGHQVSHILDSYHVISRKRRKRKRSEGLSQETTL
SQNLIQHSCSPA------------------------------------------------
-DHSEPEARTELQKKKKKKRRKRKPELQQ-------DEESEHPGDQRSPRPSVIPVP---
-------------------GSSVNGHLPSDRLGL---------GQAPLVTWNRDEEPDVV
QALLQDSSDKAYGKKVLTWDGEPSAISQDAIKDSRLARTQTVVDDWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKVASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVIPDHSKKNIGNGIISSPLTG
KRQDSGMMKKPH-ITEEIGVPISRNGSTLGLKSQNGCIPPK---------LPSGSP----
--SPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSP--RTAQELPGTSNSNSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKGNDES---AGLDRRG------SSSSSP---
---EHSASSDSTKAPQTPRSGAAHLCGSQETNCSTAGPSKTPPSGADSKTVKLKSPVLSN
T-TTEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVHRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGTSEPRS
CS-SISTALPQVNEDLVSLPHQLP--EASEPPRSPSEKRKKTFVGELQRLGSETRLPQHI
REATAAP-HGKRKRKK-KKRPEDTA--------ASALQEGQTQ-RQPGSPTH--R--REG
QAQLPAV--RRQEDGTQPQV------NGQQVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPEAMEESPRKKKKKK--RKQEPQRA------VEEDGHLECPRSAKPQDAVVPE--
---------------SSSRAPSVNGWCPGDRMGL---------SQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRQARTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------

PF00443 // ENSGT00890000139343_3_Domain_3 (292, 551)

DAHEFLRYT
IDAMQKACLNGCTRLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKSDVLSGENAYMC-A--------------------------------
--------------RCKKKVPASKRFTIHRASNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHCSNIKV
VLNQQAYVLFYLR-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDSELGKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRPKSGNEP-QAKRQG--SERFSGSSSDG
VPAPQKVLFPTEQLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATVQCLTYTPPLANYLLSREHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QATNIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCRKKVPASKRFTIHRTSNVLTLSLKRFANLSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHASNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRASST-LPSRQ-SVVPDHTKKSAGNGVTSLPTTA
KLQGPVPMRKPQ-APEEIGVPVSRSSSLPGPKLQNGYVPTK---------SPLGSP----
--TPRLAHTPTHMPALLDENGKKAKKQVPSQHCSLPLRTSPGT--------SE---PGSR
RRGSWDSGDTVVSTSPKLLAGAPANGHGLKGEDKS---ADLEKGT------SSSSSP---
---EHSSG-SSPEVLQAPEGRVTCVSDSQGTNSPTAGLSKALPNGLNSKMVKLKSPVLGS
T-AIEHMSLMSPPPAKKLALSAKKAS-TLRRATGNDLRSPSPSPLSDLTYPMTVTHPVVA
STWPVSKSRALSP------------APQSSSCPKPPVSTPSA-SLSSSIPQAPWTSEPQS
CS-STRTAMPQVNGNLMSPSYQPL--EASEASWSPSRKRHRSPVGKPQMLGPEACVSQLL
GGAAAVP-RKKRKKKK-RKGPE------GMAM-AIPQEQR---QGSPWSPKS--K--KKG
LSGLPAH--PREEGDTQPQE---------------DSQPVSSRKRKRRAA-EGLCEEAGL
LQGPPWHSSCTSKGH---------------------------------------------
---GQHEDKAESPRKKKRKK--RRPEAQQE------EEENQHPEDPRSTKPSVTT-----
-----------------GSELSVNSQLPGDRPGL---------GQAPLGPWNREREPDVV
QELLKYSSDKAYGRQVLTWDGELSAVSRDAMEDSRLARTQTVVDEWDEEFDRGKEKKMKK
FKKEKKRNFNAFQKLQSRRNFWSVTHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSAEDSELGKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRPKSGNEP-QAKRQG--SERFSGSSSDG
VPAPQKVLFPTEQLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATVQCLTYTPPLANYLLSREHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPISFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QATNIVRALELFVKPDVLSGEIAYMC-A--------------------------------
--------------KCRKKVPASKRFTIHRTSNVLTLSLKRFANLSGGKITKDVGYPEFL
NIRPYMSQSNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHASNVKV
VLNQQAYVLFYLRASST---------------LPSRQ-SVVPDHTKKSAGNGVTSLPTTA
KLQGPVPMRKPQ-APEEIGVPVSRSNSLPGPKLQNGYVPTK---------SPLGSP----
--TPRLAHTPTHMPALLDENGKKAKKQ----HCSLPLRTSPGT--------SE---PGSR
RRGSWDSGDTVVSTSPKLLAGAPANGHGLKGEDKS---ADLEKGT------SSSSSP---
---EHSSG-SSPEVLQAPEGRVTCVSDSQGTNSPTAGLSKALPNGLNSKMVKLKSPVLGS
T-AIEHMSLMSPPPAKKLALSAKKVGVGVSSLEVSQG--PSRGAVV------EEGKVVGD
SNCPVSEEQV--P-----------------------LRLP--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFQPASKSFSYQLDSLKSKYVLLNPKTEGASRHKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPISKTGSSSLPSRL-SLAPDHSKKNIGNGVVCSPLTG
KRQDSGTMKKLH-TTDEIGVPVSRNGPMVGLKSQNGYVPPK---------LPSGSP----
--SPKLSQTPTHMPTLLDDPGKKVKKPAPPQHSSPSPRTAQGPPATSNSSSSR---SGSQ
RQGSWDSRDGVLSTSPKLLAAATANGHGLKGNDES---AGLERRG------SSSSSP---
---EHSSSSDSSKAPQAPRSGTARLCNSQERNCCTAGHSKTPPSGADPKTAKLKSPVLSS
A-AAEPPSTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
SAWPVGRARAVSP------------APQSSSRLHPLFS-PHP-TLLSSTPKPPGTSEPRS
GS-SISMALPQVNGDLVSLPHQLP--EASEPPRSPSEKRKKTLMGELQRPSSETCLSQYI
REATASS-HGKRKRKK-RKRPEDT-------A-AVTLQEGQTQ-RQPGSPTH--G--REG
QAQLPAV--RWREDGTQPQV------NGQQVACVPDGHHSSSRKRRRKGA-EGLSEEGGL
HQDPPWHRSCSPM-----------------------------------------------
-GDGDPEAMEESPRKKKKKK--RKQEPQRA------VEEDGHLEGPRSAKPRDAAVP---
--------------ESSSHAPSVNGWCPGDRMGL---------GPAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEESRLARTQTVVDDWDEEFDRGKEKKIKK
YKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRRKSGDEP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVVPDHSKKNIGNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGSTLGPKSQNGYVPPK---------LPSGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGASSSSSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTARSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGMSEPRS
CS-SFSTALPQVNEDLVSLPHQLP--EASEPPRSPSEKKKKTFLGELQRLGSETRRPQHI
KEATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPGSPTH--R--REV
QAQLPAV--RRQEDGTQPQV------NGQQVGCVTDGHHASSRKRRRKGA-EGLSEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQRA------VEKDGHLEGLRNAKPRDAAVPK--
---------------SSSHTPSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEVLKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEEASRHKSGSEP-QARRQG--GEHVYESCTDG
VPAPQKVLFPTEQLSLKWERVY

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLHNLGNTCFLNSTVQCLTYTPPLANYLLSKEHA
RSCHQGGFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALEVFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFSIHRASSVLTLSLKRFANFTGGKITKDVGYPEFL
NIRPYMSQSNGEPVMYGLYAVLVHSGYSCHAGHYYCYVKVSNGQWYQMNDSLVHLSNIKV
VLNQQAYVLFYLRIPGSKKSPEGSISRTAST-LRSHP-SVLPDHLKKNISNGVASSPLTG
KRQDPMMT-KLH-LTEELGMPISRNGSVAGLKPQNGNVLPK---------LPLGSP----
--SPKPSKTPVHRPTVLDEPEKKAKKCAPLQHFSPSPKTPQGPLGAGDLNGSK---LESR
RLVSWDSRDAVLSTSPKLPPEASTNGHGPKGREQS---PDLERED------SCSSSP---
---DHSAGSDATRAPQAPKSGAAHFCDSQETNCPAGGRPKALPNGADVETVKLKSPILSN
A-TTEAASIMSPPPAKKLALSAAKKAHTLWRATSTDLRPPPHPPSSDLTRPLKATYPVGA
ATGPASQTRAVPH------------LPTPSSRPRPPFSPYTTCPSLPVSSQPLRRAEPQS
GS-SGPAAWPQVNGASASPLYQPQ--EAGEASQSVSKKRKKRRVGEMRGRSPETHSSQLS
GDAAAVPRVKRRRKK--RKRTEF--------DGVSTLQE-----RPAWTQNQSHGVEKWS
GVELPAD--RLQE------------RGGQPVGHVTDAHHVGSKRKKRKRV-EGLHEEEGH
PQDSALHSRCSPS-----------------------------------------------
-DDAQPETAAESPRKKRRKKQ-RKCESQQE------VEENEHQNSQRCDRQSDLLVPK--
---------------LSGHSPVVNGRCPCGKRGQ---------TCVPLVPWNTERESDVV
QELVRYSSDKAYGRKVLTWDGEMSAVSRDAIEDSRLAWAETVIDDWDEDFDRGKEKKIKK
FKREKKRTFNAFQKLQNRRNFWSVTHPAKATSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRRKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPMERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPSRP-SVVPDHSKKNVGNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGSTLGLKSQNGYVPPK---------LPSGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDAVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTARSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGMSEPQS
CS-SFSTALPQVNEDLVSLPHQLP--EASEPPRSPSEKKKKTFLGELQRLGSETCLPQHI
REATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-TQPGSPTH--K--REG
QAQLPAV--RRQEDGTQPRV------NGQPVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQRV------VEEDGHLEVLRNAKPRDAAVPE--
---------------SSSHTPSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDSIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGAGCHKSGDEP-QARRQG--SEHAYESCGDG
VPAPQKVLFPMERLCLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSREHA
SSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCARLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDALSGENAYMC-A--------------------------------
--------------RCKKKVPASKRFTVHRASNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNAGEPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPISKMAPS-LPRRP-SLAPDHTKKNVGNGTVSSLLTG
KRQDSVTPKKLH-TTEEIGVPVSRNGSVPGPKSQNGYVLPK---------PPAGSP----
--SPKPSQTPTHAPTVLDDPGKKVKKSAPLPPTGTGR-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFQPASKSFSYQLESLKSKYVLLNPKTEGASRHKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQTFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPISKTGSSSLPSRP-SVAPDHSKKNIGNGLVCSPLTG
KRQDSGTMKKLH-TTDEIGVPVSRNGPMVGLKSQNGYVPPK---------LPSGSP----
--SPKLSQTRTHMPTLLDDPGKKVKKPAPPQHSSPFPRTAQGPPATSNSSSSR---SGSQ
RQGSWDSRDGVLSTSPKLLAAATANGHGLKGNDES---AGLERRG------SSSSSP---
---EHSASSDSSKAPQAPRSGAARLSDSQERNCCTAGHSKTPPSGADPKTAKLKSPVLSS
A-AAEPLSTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
SAWPVGRARAVSP------------APPSSSRLHPSFS-PHP-TLLSSTPKPPGTSEPQS
GS-SISMALPQVNGDLVSLPHQLP--EASEPPQSSSEKRKKTLVGEFQRPGSETCLSQHI
REATASS-HGKRKRKK-RKRPEDT-------A-AATLQEGQTQ-RQPGSPTH--G--RED
QAQLPAV--RWQEDGTRPQV------NGQQVAYVPDGHHESSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPEAREESPRKKKKRK--RKQEPQRA------VEKDGHLEGPRSAKPRDAAVP---
--------------ESSSHAPSVNGWCPGDCMGL---------GPAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKVSAVSQDAIEESRLARTQTVVDDWDEEFDRGKEKKIKK
YKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRRDSADDGELGRLLASSAKKVLLQK
LEFEPASKSFSYQLESLKSKYVLLNPRPEGAGCPKSGGEP-PG------GELASDGDGDG
VPAPQKVLFPGERLSLRWGRVYRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTVQCLTYTPPLANYLLSREHT
RGCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLRKIARHFRFGNQEDAHEFLRYT
IDAMQKACLSGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKEVGYPEFL
NIRPYMSQSNGEPVLYGLYAVLVHSGYSCHAGHYYCYVKASSGQWYQMNDSLVHASNIKV
VLNQQAYVLFYLRIPGSKKSPQGSISRTASS-LPGCP-GAALDHVKKSVSNGPASSPPAG
KRPDPAMMKKPQ-TPEELGVPVARNGSVSGLKPQNGYAPPK---------PPVGSP----
--SPKLSKTPTHAPTLLEEPGKKVKKPAPPPPLSPPPRPSQGPRGAGE---------PGG
RPGPWGGKAS-LSPSPRPLAPGTANGLGPQAGDGG---SAAERRG------SGGSSP---
---ERSAGSGPARNPQAPQGGSTHLCESQGTP------SRGPPAQEDARLAKAKCPILSG
A-APEPANTMSPPPAKKLALSAKKAS-TLRRAASSDLRPPPLSPSSDLTHPRKPAHPAAA
STWPRSTIRAVSP------------APRPSSHL--------------NSPQPLRTSDPQS
CS-SASAPLPQVNGGFQAPPHQPP--EASEPPRAPVRRSGS----PTEDQGCETCTA---
---AAAP-PGKRRRRK-RKHTGDV------AA-SSPAPQEGLLQGQPWSPKR--R--K--
------------EEGGQQQG------NGWPGGCVSDSHQVNSRKRRRKGA-EGLGGEALA
R-DPP-------------------------------------------------------
------------------------------------------------------------
----------------------------------------RRLGQTPLVSWDGEKESDVV
QELLKYSSDKAYGRRVLTWDGEVSAVSRDAVQDSRLARAATVIDDWDEAFDRGKEKKVKK
FKREKKRNFNAFQKLQSRRNFWSVTHPAKAASLSHRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNTKAEGANHYRSGEEP-QARRQTQGGEHGHESCADG
VPAPQKVLFPMERLSLKWERVY

PF00443 // ENSGT00890000139343_3_Domain_2 (203, 240)

RVGAGLHNLGNTCFLNSTVQCLAYTPPLANYLLSKEHS
RNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKPDVLSGENAYMCAXXXXXXXXXXXXXXXXXXXXXXX----------
-------------------------XXXXX--XXXXXXX-XXXXX---XX------XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00443 // ENSGT00890000139343_3_Domain_5 (520, 551)

ASNGQWYQMNDSLVHSSNIKV
VLNQQAYVLFYLRIPGSKKSPEGSISRSVSS-LSNRP-SLVTDQLKKNISNGAVASPLTS
KRVDPVTMKKLQ-TTEEIGVPISRNGSVSGLKSQNGYASPK---------LSLGSL----
--SPRFSKPLTHLPTILDEPGKMLKKSLAPQHGSPTPKAAPGPPGSSALSGSR---PESR
KQGSWDRGT-TLSTSPKLPAAVTANGHGPKAGSEG---SDSDRRG------SSSSSP---
---EHSSASDVAKPPPPPRSRDIHFCDSQGTD------SKVLPAREDPKTVKPKCPVLST
T-TPEPASTMSPPPAKKLALSAKKXX-XLRRATSNDLRP-PLSPLSDLTP-GKTTHTIVA
-SAPVSAVRAIAP------------APRSSSHLKTL-GPCS--LSLSSGPQPLGMSDPPS
CP-SASASLPQVNGGFESPPHQLQ--EASQHPQSLCESRKRQ-LGEILGQGSETRSAS--
-----AP-PGKKR-RKKRKHMEDM--------DTSPLQEGQAQ-RLPRSPSP--KRGKEG
RIEPLTE--RLKEMGGQQQV------NGQQMDSVTSGQHMSTKKSRQE--TESLRAGGCL
HKDPPLHSSSPL------------------------------------------------
-DAVHPEPIPTSLRKKKKKK--RKPESQQE------IELNQHPRSQSAAVPEPQ------
---------------PSIPSPPVNGWCPGNSTK----------EQDPLVSWNREKKSDVV
QELLRYSSDKAYGRKVLTWDGELSAVSQDAIRDSRLACTATVIDDWDVEFDRGKEKKLKK
FKREK-RNFNAFQKLQSRRNFWSVTHPAKVTSLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASCHKSGDEP-QTRRQG--SEYAYEGCGDG
VPAPQKVLFPVERLCLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNSTIQCLTYTPPLANYLLSREHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDALSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNSGEPVTYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGPISRTVHS-LPRRP-SMVPDHTKKNVGNGIVSSPLTG
KRQDLVTTKKLH-TTEEIGVPISRNGSDPGLKSQNGYVLPK---------PPVGSP----
--SPKLSQTPTHAPTILDEPGKKVKKSAPLQHFSPPLKTSQGPPGTSTLSSSK---CGSR
RQGSWDGRDAAHSTSPKLLARATANGHGPKGSNGG---SDPERGH------SSSSSP---
---EHSASSDSAKGPRTPKSGAAPFCDSQETNGSATGHSKAPPNGADPKVVKPKSPALSN
S-APEPASIMSPPPAKKLALSAKKAS-TLRRATGSDLRPPPPSPSSDLTHPMKTSHPAVA
AAWPVPEARAVPP------------APRPPSRPQPPIS-PNS-ASLSSHPQPLGTSEPRS
RP-SASTAMPQVNRDSTSLPHQLP--EASESPRSPSEKKKKSYVGQLQGPGSETCLPQHL
EGAAAAPAPHEKKKKKKRKRP-------GDVA-TAVPQEGQTQ-GRPWSPEC--R--KKG
QTELPAD--GPEDRGTWPQV------NGQQMGRVVGGHHVSNRKRRRKGV-EGLGEEDGL
HQDPPWHSCSPT------------------------------------------------
-DSGEPEPMAESPRKKKRKR--RKPESQQE------AEENKPPEGQRSTGPRDAAAP---
-------------------EPSGSRQHPGGRVGL---------VQAPLVSWNRERESDVV
QELLKYSSDRAYGRKVLTWDGEMSAVSRDAMEDSRLARAETVVDAWDEEFDRGKEKKIKK
FKREKKRNFNAFQKLQSRRNFWAVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLAASAKKVLLQK
IEFEPASKSFSYQLESLKSKYVLLNPKTEGASRRKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPSRP-SVVPDHSKKNIGNGIVSSPLTG
KRQDSGTMKKLH-STEEVGVPISRNGSTLGLKSQNGYVPPK---------LPSGSP----
--SPKLPQTPTHIPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSSSSSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKRNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTARSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSN
A-TAEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVRRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGMSEPRS
CS-SFSTALPQVNEDLVSLPHQLP--EASEPPRSPSEKKKKTFLGELQRLGSETCLPQHI
REATAAP-HGKRKRKK-KKHPEDTA--------ATALQEGQTQ-RQPVSPTH--K--RQG
QAQLPAV--RRQEDGTQPQV------NGQPVGCVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPETMEESPRKKKKKK--RKQEPQRA------VEEDGHLEVLRNAKPRDAAVPE--
---------------SSSHTPSVNGWCPGDHMGL---------GQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRLAQTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQK
IEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDP-PARRQG--SEHTYESCGDG
VPAPQKVLFPTERLSLRWERVFRVGA

PF00443 // ENSGT00890000139343_3_Domain_3 (207, 551)

GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHA
RSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR
QAANIVRALELFVKADVLSGENAYMC-A--------------------------------
--------------KCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFL
NIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKV
VLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRP-SVIPDHSKKNIGNGIISSPLTG
KRQDSGTMKKPH-TTEETGVPISRNGSTLGLKSQNGCIPPK---------LPSGSP----
--SPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSP--RTAQGLPGTSNSNSSR---SGSQ
RQGSWDSRDVVLSTSPKLLATATANGHGLKGNDES---TGLDRRG------SSSSSP---
---EHSASSDSTKAPQTPRSGAAHLCDSQETNCSTAGPSKMPPSGADSKTVKLKSPVLSS
T-TTEPASTMSPPPAKKLALSAKKAS-TLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVA
STWPVHRARAVSP------------APQSSSRLQPPFSPHP--TLLSSTPKPPGTSEPRS
CS-SISTALPQVNEDLVSLPHQLP--EASEPPRSPSEKRKKTSVGELQRLGSETRLPQHI
REATAAP-HGKRKRKK-KKRPEDTA--------ATALQEGQTQ-RQPGSPTH--R--REG
QAQLPAV--RRQEDGTQPQV------NGQQVGYVTDGHHASSRKRRRKGA-EGLGEEGGL
HQDPPWH-SCSPM-----------------------------------------------
-GDGDPEAMEESPRKKKKKK--RKQEPQRA------VEEDGHLECPRRAKPRDAVVPE--
---------------SSSRAPSANGWCPGDHMGL---------SQAPPVSWNGERESDVV
QELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEESRQARTETVVDDWDEEFDRGKEKKIKK
FKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR

------------------------------------------------------------
---------------------MPIVDKLREALKPGRREPASDGELSRLLATSARKVLLQR
IEFEPAARSFSYQLDSLKSKYVLLNARTEGDSRPKNGEEP-PARRAG--SEHVFEDGSDG
VPAPQKVLFPTERLSLRWERVF

PF00443 // ENSGT00890000139343_3_Domain_3 (203, 551)

RVGAGLHNLGNTCFLNSTVQCLTYTPPLANYLLSQEHA
RSCHQGGFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYT
IDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSQCKSVSDTYDPYLDIALEIR
QAANIVRALELFVKPDVLSGENAYMCAXXXXXXXXXX-----------------------
------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXDVGYPEFL
NIRPYMSQSSGEPVTYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVRV
ALNQQAYVLFYLRIPSSKRSPAGPISRTSSA-FPGRP-AGTPDPSRKSFSLGSTHSPLPG
KRQDSLLGKKPQ-AAEELGVPVSRNGSILGLKTPNGHGPPK---------LPPGTP----
--SPRLPQTPTHVPTVLDEPGKKVKTPAPMQHPPPSPKTSQGFAGTSTSNGGKCGAPGGR
GQGSWDRGVTALSTSPELLAEATASGHGPKRRDGY---ADLNS-----------CSP---
---KHSSSRDSAQAPQTPKCGAARLCDSQETNCPATGHAKAPPAGADPKVARLKCP----
----EPASATSPPPAKKPALSAEKAS-SLRRATRSEPRSPLPSPFSDLTYPMTATHRAKA
STWPVSQPRAVSP------------APPSACHAKPPVSPHSTP---LHSPQP-----PRS
CS-PTSSSLPQVNGGAVAPSYQLP--EASRAPQSSSKKRKRT-CGDSRGLGPEAPLTGPL
EAEAAVPRRKKKRKKR--KPLED----------AAGHQAGQGP-------------GREG
PAELPAS--PPEAAGTWPAV------NGQQGGHGLGGQRSRKRKKKQA---DKPGRADGL
ALGTPRHS----------------------------------------------------
---GEPGPRAVSPRRKK-----RRQESEQE------AEETKRPQGQGSAQPRDAVVPG--
---------------RSHPLALVNGQLPGDCTGL---------GQ---------------
-------AAPARGDRELTWDGEVSAVSRDAAEDSRLARTQSVLDDWDEEFDRGKEKKVKK
FKREK-RNFNAFQKLQSRWNFWSVTHPAKAASLSYRR