ENSGT00880000138027_0 : Linker Region Query Results

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-----------MMSSI-----------ISLYFRMQDLNEQQRVA----------------
----EAILAQGINAGQLPCPRPFSGDRREYYQFIVLCQLILQSC-PTRFYSDRLRAQYVI
NHLSGFALEWAESLIQENSPVLENFPAFLEAMSEAFEYRYSLRV--AEEAMFYIRQGNRT
ATEYITEFQSLIPTLRWPDEVLQAHLCHGLSEDIRHYLF-RVPQPDSLDSLIVLILQIED
KLEERRAMLRLSPEAHPRN--LAWLDSPAA-------------EKWMVSSWLPY-----S
YHPDI----------------N-RAHFFVLLLVRVSPYH---SVAVQA------------
---------------------------------------------LVDSGLESNYMDENF
AQEHYVELYEK-------ASPDVVQ----TREGSVVREEPVWLYTEALVCMQQNHQESIS
FNIVPSPQ-----FSVVLGLSWLRLHTPDVDWIRGRCTFHSPYCLK--------HCFQPA
PPCIALERYSISLLPGLPH---------------------------PY------------
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----SDLADVFNPREADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-EV-FYECPSSVAWEPVGAELQEEARL-------------QEEYWDLH-
----DML--------TDRQDY---------------------------------------
---------------------------------MQMIPELFDQLHG-AAWFTRLEL-R--
---G--TIVEE----SGSRTE----D--------TWRAAFGLEIQDMKSYRPFAYSPDPI
IPQNVIHFILKDMLGFFVLSYG-QEVLVYSMCQEEHVQHVRQVLVRFRRHRVYCSLGRSQ
FHRQSGEILGFHVSPKGVKIN------KSVIDVIMGYEIPNSRRELQSMIEYMLPYRHFV
ERFAIIAEPLVRLLLS-------FEHFSWGDEEQEAFECL--------------------
-----QRAFRRAPRLHHPKPQNPFYLETG----ITFSALHASLIQID-----EHTGRRVA
C-AF-------YSRNLS-------PMEAEYPVVETKILPVRASFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDIMEVSDLDG
NWP---PPLVSSYNQRAC---RNRVARP--------------------------------
-------IL----------------FLATGGYP--------QE-----------------
-ET---------------------------------------------------------
-S------------DSE---SEESDNLTQQGELNERSLQQELLALIPIDYIFNRFL----
----VNFSMAQIR---------------------AVLLHFFRGILHWRSVLAPA------
----SLLMMLQ----------------ARQRPTLLPAPTMQVARLPPR------PSLRLV
LDSTDTVSNTMATAVAQLFSQLPPFVGANPIPPRELADL--FLSPRRW-QRNALTPLPPG
GLRFTPGFWLMLCEFFGVRATRAQPGRPA-LRHQRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQASDVQET-----------------------------LSPEE
AAEAPLRTHNPMDPDVLDILNSRLLYVPGPDGRLSLLSREQV--AQALTQFLTTIYARAA
QAPAPAGDQPGGEASLEELPDLEDDDL--D--------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVWGE---------------------------------------------------AGPA
SRPAQEKKEPPSGPLQEMEELPTDLLQDME------------------------------
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----------------------------EPSSGPRKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
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---------DPLSGA---SDRMKE-ASVNPLGAREEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMTRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFYNDRLRVGYVI
NHLSGLALEWAKALLQENSPLIGDFPAFLEAMSEVFEYRQALRV--AEEAMFTIRQGGRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPDI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
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----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------REEYWDLQ-
----DML--------TNRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AEWFTKLEL-R--
---G--TIVEESE--NGHRTE----D--------VWKAAFGLELEEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFFVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIVTGYPTPGSKLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SYQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----DQTGKRAC
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TP----------------LLASRGFP--------RD-----------------
-PA---------------------------------------------------------
-M------------ESG---EEENEE---QDESNEQTLRQELLALIPIDQILNSFL----
----AHFSVAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSLRPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALVGANTIPAQELAEL--FLGPGRW-QRNALHSQAHR
GLQFTPGFWLTLCEFFGVRVTPQEGHLPA-LRQNRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTAA
AHPPRPR--HLMDPQVLEFLGSRLLHIRSADGQLHLLSREQA--ATALSRFLTLIYRRAL
PIPAWE-SQPREQARLEELPDED-EDA--DLD------

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----YRN-KR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQSQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREV--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
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-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
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--------------------------------------------------------MRNK
RILRTKR-RK------------GGRGGQDPGPHPLRSEA---------------------
---AAGRSPPTL-AITLGPDCPP-----------------------PPPPPPPNHPSSS-
C-----------SKHCGQKG--QY-ANLTERKRDDLSEEINSLREKVMK-----------
---QSEENNNLQSQV---QKLTEENTSLRE------------------------QVEPTP
QAEEDEE---------------------------EDIE-LRGAA------AAAAPAPP--
-SE-EEC--------PEDLPEKFDGNPDTLAPFMSQCQVFMEKS-TRDFSVDRIRVCFVT
SMMTGRAARWASAKLEQSNYLMHNYPAFMTEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYCNAFQMIAQDLDWNEPALIDQFHEGLSDHIQEELS-HLEAAKSLSALIGQCIHIER
RLARAA----AARLQRSPPRALTLPHTSG--HHQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADSCPAKASKA--SPAGNSP
APL---------------------------------------------------------
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MADQMQRDLTNIEETLLPTDEMIEPSEDSFETMMERKNPSSKQMESSEGSSNTAVETEGS
GEQEE---------------------------------------------------AGPA
KGPAQESKEPPSGSGQEIEELPTDLLQDME------------------------------
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----------------------------EPSSGPCREIEDPPNDLLQDM-----------
------------------EESCNGS-HQAME-----------------------------
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---------GSLNEA---SDGTEE-TLVNPSGSQEDQDDKTNLASGGT-----SLEE-ET
QTEGPSEDIRATMRSI-----------ISLYFQMQDLNEQQRVA----------------
----EEILVQGINAGQLPSPKPFSGDRREYYEFIVLCQMILQSY-PTTFCSDHLRVKYVI
DHLTGFALEWAESLIQQSSPVLENFSAFLEAMSEVFEYKYTRRV--VEEAMFNIRQGNRT
ATEYITEFQSLIPTLGWPDEVLQAHLCQGLSEEIRHFLF-RIPQPDSLDSLIVLILQIED
KLEERSAMLRLPPESRPRS--L--MDSPAS-------------EKWTVSSWLPY-----S
FHPGI----------------N-RAHVFLLLLVRVNPYH---SIAVQA------------
---------------------------------------------LVDSGSEGNFMDENF
AQEHYVELYEK-------PYPEEIH----TVDGSLIGQEPVWLYTEPLVCMHQNHQESIE
FDIIPSPN-----FSVVLGVNWLRLHSPDVDWIQGRCTFHSPYCLK--------NCFSPP
PPCIVLERHSVSLLPGLPH---------------------------PY------------
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----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-EI-FYECPSTVPWEPVGARMQEEARL-------------QEEYWDLH-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-ATWFTRLEL-R--
---G--TIAEEGV--NGSRTE----D--------TWRAAFGLEVQDMKSYQPFTLSSDPI
IPQNVLHFILKDMLGFFVLSYG-QEVLIYSMCQEEHIQHVRQVLVRFRHHRVYCSLTKSQ
FHRHCGEILGFRVTPKGVKIN------KGVIDVIVGYSTPRSRKELQSMIEFMFPYRHFV
ERFAIIAEPLVQLLLS-------FDRFHWGDEEEEALECL--------------------
-----KRAFRRAPLLHHPKPQNPFYLETG----ISTSALYTSLIQVD-----EHTGKTVT
C-AF-------YSRNLS-------PMEVDYPLVEMKVLPIRASFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMDLPVLDG
SWP---PPAWRSCNQRAL---RNRVARP--------------------------------
-------IL----------------FLATRGCL--------PD-----------------
-ET---------------------------------------------------------
-S------------DSE---SEESDNLSEQDELNELNLQQELLALIPIDHIFNSFL----
----ANFSMAQIR---------------------SVVLHFFRGLLHWQSLLAPA------
----SLLVMLD----------------TRQRPTLLPAPPLQVAWLEPR------HSQRLL
LDPTLTVSASMAAALTQLFGQMPPFVGANPIPPRELADL--ILGSQRR-QHNALNQLPPR
GLRFSPGFWLLLCEFFGVRATRTERGAPA-LSQPHYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQDNDVQEA-----------------------------LSPSE
---APLRPRSLMDPEVLDILNSRLLYVPGPDGRLSLLSREQV--AQALTQFLTAIYTRAA
HTPSQG------GASLEELPDLEEDEA--VEDDDTLD-

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-------------------PERFDGAREKLPTFLAQVDLYFLQISDLSFPTDTNKVAFIL
SLLTGPAGRWAVNIIRGNSPIKNNLVDFKAALTETFGDPLQKEN--AGWALYRLKQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLAFTAGLNDGLQVELS-RVEPAQNWDELVTKVCRIEA
RLEFRKKTHRTPVVEYH-----------ASAPVNSGE-EP---MQLGVQRELSQ-----E
E---K----------------D-QRRRLRLCLYCGIEGHFAHNCSLKP------------
---------------------------------------------SQLPGKGCMRSRY--
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---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVQGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLEEMEELPTDLLQDME------------------------------
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----------------------------EPSSGPHKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
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---------DPLSGA---SDRMKE-ASVNPSGAQEEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPIWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
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----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTAEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----DQTGKRAY
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFEVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDESNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSVLPAPTMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGRW-QRNALHSQTHR
GLQFTPGFWMTLCEFFGVRVTPWEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTGA
SPPPRPR--HLMDPQVLEFLSSRLLHIRGADGQLHLLSREQA--VRALSQFLTLIYRQAL
PVPAWE-SQPREEARLEELPDED-EDA--DLD------

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--------------------------------------------------------MRNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIK-----------
---QSEENSNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDDD---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHVASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SPGKLPG
PAVEGPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
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-----------P---------------------PAQQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
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-------------------PERFDGTREKLPTFLAQVDLYFLQISDLSFPTETNKVAFIL
SLLTGSAGRWAVNVIRGNSQIKNNLVDFKAALNETFGDPLQKEN--AGWALYRLKQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLVFTAGVNECLQDELS-RVEPAQNWDELVTKVCRIEA
RMEFRKKTRGTPVVEYH-----------ASASVNSGE-EP---MQLGMQRKLSQ-----E
E---K----------------D-RRRRLRLCLYCGNGGHFAHGCTLKP------------
---------------------------------------------SQLPDSWDVSAKR--
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---------------------------LITLHLPD--GS---YCTVRA------------
---------------------------------------------MIDSGASGNFIDQDY
VAQTGIPVKIK-------YWPVLVE----AIDGRPLASGPVTQETQELVVDIGEHRERLS
FDVTQSPF-----FPVVLGVRWLTQHNPSIMWSSRTIVFDSEYCQH--------NCRAAL
LMAPS------MVPAG--------------------------------------------
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----MDVQEVLVPVAQEAVPYHAPYNYAVAPA------------------GCPYAVSDP-
ELMAVRDFLAK-NV-KWVC--VQPASPVGAPVVIMKKVGELYLCNDSQNPNAIAVWNQY-
----PP------------------------------------------------------
----------------------------------PSAPYVLYQLQA-APIYRTRSP----
------------------AGY----T--------TWS-MLGREMSGKLCLIPFLVTSNSL
WGLEPRFVP---------------------LPRTEP-PPPEASLHTLSGPPSCCPL----
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---------------------------------------------------M----DLLN
RVLRTKR-RR------------GGRGGQDPGLHPQRSEV---------------------
---AAGRSPPTPIITTMGPADCP-----------------------PPPPPPPPHNNNN-
NKPCGH------------NS--SCMPNMTERRRDELSEEINNLRDKVIR-----------
---QSEENNNLQSQV---QKLTEENSTLRE------------------------QVEEEA
PIPEEED---------------------------DDLE-LQGAA------AAAPPPPP--
-IE-EES--------PEDLPEKFDGNPDMLAPFMTQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREV--AKRKIRRLRQGMGS
VVDYANAFQMIAQDLDWNEPALIDQFHEGLNDRIQEELT-QVEVPNTLCGVIGLCIHLER
RLARAA----AAAAPRSPPRATAQP---SH--PQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNC-----------GKLPG
PAVEGPSATGPEIIRSPQDDAVSSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPIRVK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLADHREVIS
FDVTQSPF-----FPIVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCQM------YSPI
PPSLP-------------------------------------------------------
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----------PS-----------------------PQPSLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPNIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQVPGYQTYPAY-----------------
----------------T-TYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTM---------------------
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--------------------------------------------------------YRNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPHNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHVASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SPAGNSP
APL---------------------------------------------------------
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-------------------PERFDGSRNKLPTFLAQTELYFSQISAQAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNDFKKLLSDTFGYPLRMEN--ASWALYRLKQGKGS
VLDYLNKFNSYRHQLDWGENAFMLLFIAGLNDHLQDELA-RLEPAENWDALVAKVLRLDA
RFESRKQSRAMYAPTVS-------A---PRAPVAKGE-EP---MELGVFRKLST-----A
E---K----------------D-RRRQLGLCLYCGNAGHFARNCNVKP------------
---------------------------------------------SQLSGKAGVPKLR--
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-------------------PERFDGTREKLPTFLAQVDLYFLQISDLSFPTDTNKVAFIL
SLLTGPAGRWAVNVIRGNSPIKNNLVDFKAALNEMFGDPLQKEN--AGWALYRLKQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLVFTAGLNECLQDELS-RVEPAQNWDELVTKVCRIEA
RMEFRKKTRGTPVVEYH-----------ASASVSSGE-EP---MKLGMQRKLSQ-----E
E---K----------------D-RRRRLRLCLYCGNGGHFAHGCTLKP------------
---------------------------------------------SQLPGRSGNLAPAR-
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---------------------------MTERRRDELSEEINNLREKVIR-----------
---QSAENNNLQSQV---QKLTEENTTLRE------------------------QV--EP
IP-EEEE---------------------------DDIE-LQGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMEKS-TRDFSIDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQFHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAA----AARKPRSPPRALVMPHVANP--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKANKS--SPAGNSP
APL---------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------------------------MRNK
RVLKTKK-RR------------SGRGGQDPGLHPHRSEV---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPA--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SPGKLPG
PAVEGPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEPV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSESDMAALRDFVA-----
------RNVKDGLITPTVAPNGAQILQ----VKRGWKLQVS--YD-CRAPNNI--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
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---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTVETSGS
GVQEA---------------------------------------------------AGPA
KHPAQEREEPPSGSVQEGEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHREIEDPPNDLLQDM-----------
------------------EESCNGS-HQAVE-----------------------------
------------------------------------------------------------
---------DPLSEA---SDKMKE-ASVNPSRAQQAQEANTDLNESRREE--NPEEE-HS
QTESPTTEVMATMRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILVRGISAGRLPAPKNFSGDRREFHEFIVLCQLTLQSY-PRMFYSDHLRVGYVI
SHLSGLALEWAKALLQKNSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMLNIRQGNRS
AAEYINEFQSLVPTLRWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLESLTVLVLQIEE
KLAERRAVLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQSIQ----TVDGSLIGDEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDR--ET-FYECSSTASWEPVRARVQERAKP-------------QEECWDLQ-
----DML--------TDKQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-ATWFTKLVL-R--
---G--TIVEESV--NIHGTE----D--------IWKAAFGLEIQDMKSYQPFALSPDPI
IPQNVIHFVLKDILGFCVISYA-QEVLIYSMSQEEHLQHVRQILVRFRHHRIYCSLDKSQ
FHRHTAEFLGFVITPKGVKMN------KSIMDVITAYPIPGSKKTLQNLMELVLPYRHFV
ERFAIITEPLVRLVLS-------TQEFRWGDEEQEAFECL--------------------
-----KRAFRKSPLLCHPKPQNPFYLEIG----ITGTALYTSLIQID-----DQTGKRVS
C-AF-------YSRSLS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLKTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRP---LPPGRNHGQ-RAF-RRN--TRP--------------------------------
-------HL----------------LLAMRGSP--------GD-----------------
-QS---------------------------------------------------------
-T------------ESG---EEENED---QDEPNEQTLVQELLAMIPIDQILNSIL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNVLALA------
----ALLVLLR----------------ARQCLSLPRAPTMQVARPQPQ------RSLRLI
LDSSLLSGSSITTAIAQLLTQMPPLGGVNSIPARELAEL--FLGPDRW-QRNALSSPTSG
GLQLTTGFWLMLCEFFGVRVTPQEGSHAA-PRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDEQDNDVQEA---------------------------LPSDNAV
ALPFRPR--HLMDPEVLEFLNNRLLYICSTDGQLHLLSREQA--ARALSRFLTLICSQAL
PLA-----QPREEAQLEELPHQD-EDA--EDT------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVRGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLQEMEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDL-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAREEQEAHTDLKESGREE--TPQEE-QN
QTEHSAAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFYNDRLRVGYVI
NHLSGLALEWAKALLQENSPLIGDFPAFLEAMSEVFEYRQALRV--AEEAMFTIRQGGRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPDI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-GT-FHECPSTAPWEPVGAGMQERAGL-------------QEEYWDLQ-
----DML--------TNRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AEWFTKLEL-R--
---G--TIVEESV--NGHRTE----D--------VWKAAFGLELEEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFFVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIVTGYPTPGSKLSLRNFIEFVFPYRHFV
ERFSVIAEPLVRQLLS-------SYQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTGTALHASLIQID-----DQTGKRAC
C-AF-------YSRNIS-------PIEVEYSRAEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PS---------------------------------------------------------
-T------------ESG---EEENEE---QDEPNEQTLRQELLAMIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSLRPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALVGANTIPAQELAEL--FLGPGRW-QRNALHSQAHR
GLQFTPGFWLTLCEFFGVRVTPQEGHLPA-LRQNRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTAA
THPPRPR--HLMDPQVLEFLGSRLLHIRSADGQLHLLSREQA--ARALSQFLTLIYRRAL
PIPAWE-SQPREQARLEELPDED-EDA--DLD------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVRGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLQEMEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDL-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAREEQEAHTDLKESGREE--TPQE--QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFYNDRLRVGYVI
NHLSGLALEWAKALLQENSPLIGDFPAFLEAMSEVFEYRQALRV--AEEAMFTIRQGGRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPDI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TNRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AEWFTKLEL-R--
---G--TIVEESV--NGHRTE----D--------VWKAAFGLELEEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFFVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSKLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SYQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTGTALHASLIQID-----DQTGKRAC
C-AF-------YSRNIS-------PIEVEYSQAEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PS---------------------------------------------------------
-T------------ESG---EEENEE---QDELNEQILRQELLAMIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSLRPAPAMRVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALVGANTIPAQELAEL--FLGPGRW-QRNALHSQAHR
GLQFTPGFWLTLCEFFGVRVTPQEGHLPA-LRQNRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------PPSHTAA
THPPRPR--HLMDPQVLEFLGSRLLHIHSADGQLHLLSREQA--ARALSQFLTLIYRRAL
PIPAWE-SQPREQARLEELPDED-EDA--NLD------

---------------------MIEPSEDSFETMMELKNPSSKQMESSEGSSNTVEEAPGN
SGVQAEAQAGAQVEAQEGAQVE----------------AQEGAQEEAQEEAQEEAQEGSE
SGLAQEKMEPPSGPLEEMQELPTDLTQEPS---T---RPYEEGTNDQPEDME---EESSY
GLHQEEGAQEEAQEEAQEEAQEGAQAGAQEEAQEEAQEGAQEEAQE-------GAQEEAQ
EGAQEEAQEEAQEEAQEGSESGLAQEKMEPPSGPLEEMQELPTDLTQ---EPSTRPYEE-
------GTNDQP---EDMEETSDD-SNQESSDGSNHEFDNGSNHESSCGSNQESIDVSN-
LE-SSDVSNQESSYGLHQEASYSSNQEASYSSNQEESS-------DGSNQNSIDDSNRES
SYGSNQEESDPLSDV---SDYSM-NETMTSSETQSDQDD-TDLGDEEEDD-DEDSEE-ED
PSRSSPEEVVATMGSI-----------ISLFLQMEDLEEQQRVV----------------
----ERIMVQALNEDRLPRLRPFSGDRRDYNEFIMLCQITMQNY-PVMVNNDQLKVRFVI
HHLSDVALEWANDLLEQNSHLINDFPAFLEAMSEKFEYRHTLRV--AEDAMLDIRQRNRC
AADYINEFLGLIPTLGWQDEVLQAHLCLGLNEDIRRYLF-RIPQPDSLRSLIILVLQIEE
RLAERRALLRLPPESRPRS--LAWMDSPAP-------------DKWRVSSWPPN-----E
FHPDI----------------D-RHHFFLMLLVRVNPYH---SIAVKA------------
---------------------------------------------LVDTGVEGNYMDEKF
AQEHYVELYEK-------THRQIIQ----GVDGSVIGNQLVWLCTDSLACVHQKHYEWIE
FDILPSTN-----FSIILGIKWLQTHEPEVDWCRGRCTFHSPYCLK--------NCSNPP
PPCIALENYSMSLLPGLPH---------------------------TY------------
------------------------------------------------------------
----SDLADVFNPREADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDQN-GV-FHRRRAKETLKPVSARMQEKA-------------RQQEEYWILY-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMVPELFDQLHA-ASWFTKLEV-L--
---E---VDKAEMKNSVAHTE----D--------TWRASFGFSDQQMRCYRPYTMSSFSD
ESNNIVHVILKDILGYFVICHG-REVLVYSMSKEEHPLHVRQVLLRFRYHNIYCSLDKTQ
FHRQKAEILGFSISPKGVKLS------KKLTDIMVECPVPETRRCLQGVIELFYPYRHFV
EHFSVMAEPLVKQLLS-------SEPYYWGEEEQEAFDSL--------------------
-----KRAFSRAPVLYHPKPQNPFYLETG----TVGSFLYASLIQTD-----DATGRKAT
C-AF-------YSRPLS-------LMEVEYPQVEMRILPIRAAFMVWFRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFSVMEMPDQDD
TQAL---F-RSCWNQRGFRAR---FLRPLLLMAMRAGY--MDSSSDSEDEDEDQ--DD--
-----------------------------------------------------D------
-------DEED-------------------------------------------------
-----------------------SEEDSEQIELNRQTMMRDLLATIPMDRILNGFL----
----VRFTVAQIR---------------------AVVLNFFRGLIYWRTVLGVS------
----ALLVMSRA---------------R-RPLSPLPEPSLEVARPQPR------PTLRLI
LDPTLIASSGMATAIAQLLRQMPPLVGANALPARELAEL--VLSPRCW-HRNALHSQPPR
GMRFTPGFWLTLCEFFGVRVNPEEDIFPD-PYQHRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQDNDVQED----------------------------PLGDQE
--AVTFRPRNLLDPEVLDFLNNRLLYTLGSDGRLTLLSRDQV--ARTLTRFLTMASRMAL
PSL------AREQARLEELSDSD-EEL--D--------

---------------------MIEPSEDSFETMMERKNPSSKQMESSEGSSETTVETPPG
GRAEA---------------------------------------------------AGLA
-----------GGLAQETGEQSIDLRQDME------------------------------
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----------------------------EPSSGPHREIKDPPNDLLQDL-----------
------------------EESCEGS-HLEEG-----------------------------
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---------GPFGGA---PGGMEEEEEDNPWESQEDQDYYTDLAESEEDE--SPEEP---
--DSSTVEVMGMVRSI-----------ISLYFRMQDLREQQRVA----------------
----EEILMNAINKGQLPTPKQFSGDRREYHEFIVLCQLILQSY-PRVFCNDRLRVGYVI
SHLSGMAMEWASDLVEKESSMIDDFPAFLEAMNDTFEYRQALRV--AEDAMFNLRQGDRA
AIEYINEFQSLVPTLGWPDEVLQAHLCQGLK EDIRQYLF-SIPQPNSLENLIALVLQIED
KLAERRAMLRLAPEARPRH--LTWLDSPVP-------------ERWTVSTWLPN-----E
FHPGI----------------K-RKHLFLLLLVRVNP YH---SVAVQA------------
---------------------------------------------LVDSGATSNYMDEGF
AQEHYVELYQK-------PYAELVQ----TADGSLVGNEPVWLYTEPLVCLHQNHQESLE
FDIVASSK-----FSVILGIKWLQLHAPDIDWVKGRCTFHSPYCLK--------NCFRPP
PPCIALEHHAVSLLPGLPH---------------------------QY------------
------------------------------------------------------------
----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDQSEET-FYDCASTAPWEPVDAGVQEKAK--------------QEEFWDLQ-
----DML--------TSRHDY---------------------------------------
---------------------------------IQMIPELFDQLHG-ATWFTKLEL-R--
---G--TIVEESM--DIHQTE----D--------VWKVAFGLELQEMASYQPFLICADPI
IPQGVIHFILKDMIGLFVISYG-QDVLVYSMSQEEHYHHVRQVLVRFRYHHVYCSLQRSQ
FHRHTAEFLGFVVTPKGVRLN------KSIVSTITGYPTPGSRKSLRNLMEFAFPYRHFV
ERFADITEPLVRQLRA-------DQPFDWGDKEQEAFVGL--------------------
-----KRAFRKAPLLYHPKPQNQFYLQTG----VTKTSLYASLIQMD-----KRTGKKAC
C-AF-------YSRNIS-------PMEVEASPAEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNKEDLA-----SLNNDRLTVLLPGHWVFFFAHFNFDVKEMPTSED
AQP---LPRRQRLRKRAQQSQAATTTRP--------------------------------
-------TM----------------LVTMRGPP--------GG-----------------
-QS---------------------------------------------------------
-P------------ESEN--EEESEDALHPDEPNGQNLQHGLLALIPVDQIFNSFL----
----AHFSMAQIR---------------------AVMLHFYRSLLLWKNLLAMA------
----ALLVMLR----------------FRRRLALLPAPAADPARPPPQ------RSLRLF
LETSLLTSSGIASAVTQLFTQMPPLVGANALPPEELAEL--FLGPRPWQLHS------LH
GLRITPSFWQMLCQFFGIGGPALEGTQTH-PSPR--LVPHVEGDDCVVLRDALQ--DDLQ
RFRQCGLHDGLQDTSQDAQDAQG------------------------------------G
AWARRPLQHPPTQAEAL----ARPADIRSTQGLSIVTHRELM--ARALTDFLAAVSTQAL
PTLVEA-SPPSERATLEELPSDSDEDA--DLD------

---------------------MIEPSEDSFETMMERKNPSSKQMESSEGSSNTTVETSGS
GAQEA---------------------------------------------------AGPA
S-----------GPAQEMKELPIDLRQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHREIKDPPNDLLQDL-----------
------------------EESHNGS-HQEVG-----------------------------
------------------------------------------------------------
---------DPTSEA---PGRMEE-ASVNSRGAQDQQVNDTDLANVGE-E--EHPEE---
--EPDTSEIMATVRSI-----------ISLYFRMQDLREQQRVA----------------
----EEILMEGINAGQLPV--------------------LLQSY-PRMFYNDRLRVGYVM
CHLSGMALEWARALVNEDSPLMDDFPAFLEAMSGMFEYRQALRV--AEDAMFNIRQGNRP
AIEYINEFQGLVPTLGWSDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLVLQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWTVSSWLPC-----E
VRPTV----------------T-RKHLFLLLLVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGAGGNFMDERF
AQEHYVELYEK-------PYPQMVQ----GVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVILGINWLRIHTPEVDWLKGRCTFHSPYCLQ--------KCFRPP
PPCIALERHAISLLPGLPP---------------------------LY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGAGMQKSARP-------------RDENWNPE-
----SML--------TNKQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-ATWFTKLEL-R--
---G--TIVEESM--NIHQAE----D--------VWKVAFGFEPQEVESYQPFPLSSDPI
VPQHVLHLILKDMLGYFVLSYG-QDVLVYSMSQEEHFQHVRQVLVRFRHHHVYCSLDRSQ
FHRHTVEFLGFVITPKGVKLN------KSIVNTVTGYPTPGSKKSLKHLIQFILPYQHFV
ERFGIIIEPLARLLLT-------APTFSWGDEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTKTALHASLIQID-----DQTGKRVS
C-AF-------YSRNIS-------PIEVAYSRLEMKILPIRAAFTVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMQRPALDG
GRP---LPPLRNLNRRPF--QHNTATRS--------------------------------
-------RS----------------LFLTGGLP--------RD-----------------
-RS---------------------------------------------------------
-L------------DSWE--EDENEDAPPQDKPHGRNLQQEFLALIPIDQILHSV-L---
----AHFSVAQIR---------------------AVILHFFRGLLFWKDTLAVA------
----ALLVLLK----------------LRRRLSPRPTPAW--------------------
------------------------------------------------------------
---------PVLCEFFGVRGGGPQGARPL-PGGTRSLELHVVGDEDAVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDEQ-NDVQEA-----------------------------LSPDT
TVALQPLRHLPVPADVLAFLSQHPPRVHSTAGQPDLIAQEQA--ARALIHFLTAVYTQAR
PAAVWA-R---EEARLEELPGVQDD-G--SLQ------

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-----------------------------MLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLADPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------------MVNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEV---------------------
---TAGRSPPTP-TVAMGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARKPPRSPPRALVLPHVASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPFYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSESDMAALRDFVA-----
------RNVKDGLITPTVAPNGAQILQ----VKRGWKLQVS--YD-CRAPNNI--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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---------------------MIEPSEDSFETMMELKNPSSKQMESSEGSSNTVEETPGS
SGAQAGAQAGAQAEAQAETQVEAQ----------------AEAQAEAQVEAQVEAQAGSD
SGPAQEEKEPPSGPLKEMQELPTNLLQEVE---EPSSGPHQEM-QELPTDLLQEVEEPSS
GPHQEMQELPTDLLREVEEPS----SGPYQEMQELPTDLLREVEEPSSGPYQEMQELPTD
LLREVEEPSSGPYQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSDPCEA-
------SSNDLP---QDMEESSDDGSNQESSDGSNHELSNGSNHESSFGSNPESSDVSN-
LE-SSGGSNQESSDGSQKESSYDSNPELSDNSNQELSDNSNQESSDSSN---------QS
SDISNQEGSEPLSEA---SDYSM-DETINSSETQSDQDD-TDLGDDEEEEEEEGGEE-EG
QPKNSPEEVVATMGNV-----------ISLFLRMQDLKEQQRVA----------------
----ERLMMQAINEGRLPSLRPFSGDRRDYHEFVVLCQMTMQNY-PSMLYNDELRVKFVI
RHLTDLALEWANDLVEQNSPVINNFSAFLEAMSEKFEYRQTLRV--AEDAMFNIRQGNRC
AADYINEFRGLIPTLGWPDEVLQAHLCQGLNEEIRHYLF-RIPQPNSLDNLIVLVLQLEE
KLAERRALLRLPPESRPRS--VAWMDAPAP-------------EKWRVSSWLPN-----E
FHPDI----------------D-RDHLFLLLLVRVDPYH---SVAVRA------------
---------------------------------------------LVDSGAEGNYMDERF
AQEHYVELYEK-------PYPQIIQ----GVDGIPIGNEPVWLCTEPLVCVHQKHYEYIE
FDILPSPN-----FSIVLGMKWLRTHAPEVDWMRGRCTFHSPYCLR--------NCFTPP
PPCIALETYSISLLPGLPH---------------------------TY------------
------------------------------------------------------------
----SDLADVFNPREADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDQS-GV-FYESGARETLEPVSARMQEKARQQEKA-------REQEEYWILY-
----DML--------TDRQDY---------------------------------------
---------------------------------TQMVPELFDQLHG-AAWFTKLEL-L--
---G---IKESEMRHTVTHTE----D--------TWRASFGFGLHQMRCYRPFTMNSYSD
EGNNIVHFILKDILGLFVICHG-REVLVYSMSQEEHSQHVRQVLVRFRYHNIYCSLDKTQ
FHRQTAEILGFNISPKGVKLN------KNLMNLIVGCPVPGSRRCLQSVIDLVYPYRHFV
ENFAVIAAPLVRQLLS-------SEPYYWGEEEQEALESL--------------------
-----KRAFRKSPVLYHPKPQNPFYLETD----ITGSFLSASLVQTD-----DETGKKST
C-AF-------YSRPLS-------TMEVEYPRVEMRILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFGVMEMPAEGD
TQAL---F-RRCWNQRGFRAR---FLRPLLLMSIRANLRYFDRSSETEDKEDDE--E-EE
EEDGEE-EEGEEEED---GE-EEEGEEEEDGEEEEEEEED-------DEEEEGEEEEDGE
EE--EGEEEEDGEEEEGEEEEDGEEEEGEEEGEEEEEGEEEEEE----EEDEEEEEEEEE
EEEEEEEEEEEEEEEEEEEEEDEEEEDEEEEDEEVPSMVRELLAAIPMDHILNGLL----
----AHFSVAQIR---------------------AVVLNFFRGLLYWKSLLGVA------
----AVLVMLRA---------------R-QPLSPVPAPNLEVARPQHR------HTLRLI
LDSTLIASSGMATAIAQLLSQMPPLVGANTLPARELAEL--FLGPRCW-HRNALHSQPPR
GMRFTPGFWLTLCEFFGVRVNPEDDVFPD-PYQHRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQDNDVQED----------------------------LFGDQE
--AVTFRPRNLLDPEVLDFLNNRLLYTLGTDGRLTLLSRDQV--AQALTRFLAMASRMAL
PSP------AREQARLEELSDSD-DEL--D--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MNK
RVLKTKR-RR------------GARGGQDPGLPPQRSEA---------------------
---TPGRSPPTP-IAAMGPDDCP-----------------------PPPPPPPPNNNNN-
---NN--------KPNGHQN--PCVPNMTERRRDELSEEINNLREKVIR-----------
---QSEENNNLQDQV---QKLTEENSTLRE------------------------QVEE--
-VEEDNE---------------------------DDIE-LQGAA------AAAAPAAP--
-IEEEEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMERS-NRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSNYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGLGS
VVDYSNAFQMIAQDLDWNEPALIDQYHEGLSDQIQEELS-RHEAPKTLSALISQCIHIER
RLARAA----AARKPRSPPRAMVMPQ--NH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKS--SP-----
----GPSATGPERIRSPHDDT-STPHLQVMLQIHIPGRHTLFVRAMIDSGASGNFIDQEY
VIQNAIPVRVK-------EWPIMVE----AIDGRPIASGPIVHETHNLIVDLGDHREVLS
FDVTQSPF-----FPIVLGVRWLSTHDPHITWSTRSIVFNSDYCRFRCRM------FCTI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P------------------------HPPFYYPVD-GYRV---YQPVRYF
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSESEMAALRDFVA-----
------RSVKDGLITPTIAPNGAQILQ----VKRGWKLQVS--YA-CRAPHNC--TIQNQ
YPRLSIPNLDDQ-----THLATY----AEFVPQLPGYQSYPA------------------
----------------YATYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PVTM--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVQGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLEEMEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAQEEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPIWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTAEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----DQTGKRAY
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFEVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDESNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSVLPAPTMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGRW-QRNALHSQTHR
GLQFTPGFWMTLCEFFGVRVTPWEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTEA
SPPPRPR--HLMDPQVLEFLSSRLLHIRGADGQLHLLSREQA--VRALSQFLTLIYRQAL
PVPAWE-SQPREEARLEELPDED-EDA--DLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PERFDGAREKLPTFLAQVDLYFLQISDLSFPTDTNKVAFIL
SLLTGPAGRWAVNVIRGNSPIKNNLVDFKAALTETFGDPLQKEN--AGWALYRLRQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLTFTAGLNDGLQDELS-RVEPAQNWDELVTKVCRIEA
RLEFRKKTHRTPVVEYH-----------ASAPVNSGE-EP---MQLGVQRKLSQ-----E
E---K----------------D-RRRRLRLCLYCGNEGHFAHNCSLKP------------
---------------------------------------------SQLPGKGCMRSRY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------FDGTRCKLPTFLAQVELYFSQLSAHAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNNFKKLLTDTFGDPLRTEN--AGWALYRLKQGKGT
VLDYLNKFNLYRHQLDWGENAFMLLFTAGLSDMLQDELA-RLEPAESWDALVAKVLRLDA
RFEARKHSKAMCAPPMH-------------------E-EP---MELGVFKKLST-----E
E---K----------------S-RRRQLGLCLYCGNAGHFAKNCNVKP------------
---------------------------------------------SQLSEKASPSATQ--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PERFDGAREKLPTFLAQVDLYFLQISDLSFPTDTNKVAFIL
SLLTGPAGRWAVNVIRGNSPIKNNLVDFKAALTETFGDPLQKEN--AGWALYRLKQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLAFTAGLNDGLQDELS-RVEPAQNWDELVTKVCGIEA
RLEFRKKTHRTPVVEYH-----------ASASVNSGE-EP---MQLGVQRKLSQ-----E
E---K----------------D-RRRRLRLCLYCGNEGHFAHNCSLKP------------
---------------------------------------------SQLPGKDQSFAER--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVQGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLEEMEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAQEEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPIWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----EQTGKRAY
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFEVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDETNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSVLPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGHW-QRNALHSQTHR
GLQFTPGFWMTLCEFFGVRVTPWEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTGA
SHPPRPR--HLMDPQVLEFLSSRLLHIRGADGQLHLLSREQA--VRALSQFLTLIYRQAL
PVPTWE-SQPREEARLEELPDED-EDA--DLD------

---------------------MIEPSEDSFETMMELKNPSSKQMESSEGSSNTVEETPGS
SGAQAGAQAGAQAETQAEAQAEAQ----------------AEAQADAQVDAQWRSHP---
-----------VAPTRTCKS----------------------------------------
------------------------------------------------------------
CPLIXEEPSSGPNEEMQELPTDLLQEVEEPSSGPNQEMQELPTDLLQEVEEPSSDPCEA-
------SSNDLP---QDMEESSDDGSNQESSDGSNHELSNGSNHESSFGSNPESSDVSN-
LE-SSGGSNHESSDGSQKESSYDSNPELSDNSNQELSDNSNQELSDNSNQESSDSSNQES
SDISNQEGSDPLSEA---SDYSM-DETINSFGTQSDQDD-TDLGDDEEEEE-EDGEE-EG
QPMNSPEEVVARMGNV-----------ISMFLRMQDLKEQQRVA----------------
----ERLMMQAINEGRLPSLRPFSGDRRDYHEFVVLCQMTMQNY-PSMLYNDELRVKFVI
RHLTDLALEWANDLVEQNSPVINNFSAFLEAMSEKFEYRQTLRV--AEDAMFNIRQGNRC
AADYINEFQGLIPTLGWPDEVLQAHLCQGLNEEIRHYLF-RIPQPDSLDNLIVLVLQLEE
KLAERRALLRLPPESRPRS--VAWMDAPAP-------------EKWRVSSWLPN-----E
FHPDI----------------D-RDHLFLLLLVRVDPYH---SVAVRA------------
---------------------------------------------LVDSGAEGNYMDERF
AQEHYVELYEK-------PYPQIIQ----GVDGAPIGNEPVWLCTEPLVCVHQKHYEYIE
FDILPSPN-----FSIVLGMKWLRTHAPEVDWVRGRCTFHSPYCLR--------NCFTPP
PPCIALEKYSISLLPGLPH---------------------------TY------------
------------------------------------------------------------
----SDLADVFNPREADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDQS-GV-FYESGDRETLEPVSARMQEKARQQEKA-------REQEEYWILY-
----DML--------TDRQDY---------------------------------------
---------------------------------TQMVPELFDQLHG-AAWFTKLEL-L--
---G---IKEGEMRHTVTHTE----D--------TWRASFGFGIHQMRCYRPFTMNSYSD
EGNNIVHFILKDILGLFVICHG-REVLVYSMSQEEHSQHVRQVLVRFRYHNIYCSLDKTQ
FHRQSAEILGFNICPKGVKLN------KNLMKLIVGCPVPGSRRCLQSVIDLVYPYRHFV
ENFAVIAAPLVRQLLS-------SEPYYWGEEEQQALESL--------------------
-----KRAFRKSPVLHHPKPQNPFYLETD----VTGSFLSASLVQTD-----YETGKKST
C-AF-------YSRALS-------TMEVEYPRVEMRILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFGVMEMPDEGD
TQAL---F-RRCWNQRGFRAR---FLRPLLLMSIRANQRFLDISSETEDKEDNE--E-EE
EEEEEE-EEMEEKKK---KK-KKK----------KK------------KKKKKKKKRGGR
GR-------------GGKGEGKGEEGGGRLCQYL--PNRKEWEE----EEDGE-------
-----------EEEWEEEEMEEEEEEEEEEEEEEEPSMVRELLAAIPMDHILNGFL----
----AHFSVAQIR---------------------AIVLNFFRGLLYWKSILGVA------
----AVLVMLRA---------------R-QPLSPLPAPTLEVARPQHR------HTLRLI
LDSTLIASSGMATAIAQLLSQMPPLVGANTLPARELAEL--FLGPRCW-HRNALHSQPPR
GMRFTPGFWLTLCEFFGIRVNPEDDVFPD-PYQHRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQDNDVQED----------------------------LLGDQE
--AVTFRPRNLLDPEVLDFLNNRLLYTLGTDGRLTLLSRDQV--AQALTRFLAMASRMAL
PSR------ARELARLEELSDSD-DEL--D--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------XXXXXXXXX-----------------------XXPPPPPNNNNNN-
---NS--------KPSGHKS--PCVPNMTERRRNELSEEINNLREKVMR-----------
---QSAENSNLQNQV---QKLSEENSTLRE------------------------QVEP--
-ISEDEE---------------------------DDIE-LQGAA------AATVPE----
---QEDC--------LEELPEKFDGNPDMLAAFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEVKHVFEDPQRREA--AKRKIRRLRQGLGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSRHIQEELC-HVEVAKSLSALIGQCIHIER
RLIRAA----AARKPRSPSRALVQA---QH--HQADPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKS--SP-----
----GPSATGPEIIRSQED--FLSPHLQVMLQIHLPGRQTLFVRAMIDSGASGNFIDHEY
VAQNRIPLRIK-------DWPILVE----AIDGRPIASGPIVHETHELIVDLGDHREVLS
FDVTQSPF-----FPIVLGVRWLTTHDPNITWSTRSIVFDSDYCRYHCRM------YSPV
LQCLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------PAPHPALYYPVG-GYRVYQPYQPVRYY
FVHNVYTPVDGHV-YPDHRLIDPHIEMIPGAHSIPSGHLYPLSEHEMAALREFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YA-CRGPNNL--TIQHQ
YPCLTIPNLDDQ-----AHLATY----MEFVPEVPGYPSFPVHAT-------------YP
THHTYPTXXXXXXXXTYPIYPTYPMGFAWYPVGRDGQGRV-----LFVPVVITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSCSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MAAAGGSSNCP-----------------------PPPPPPPPNN-NNN
NNTPK-----------SPGV--PDAEDDDERRHDELPEDINNFDEDMNR-----------
---QFE-NMNLLDQV---ELLAQSYSLLDH---------LDDFDDDDEDDDFDPEPDQDE
LPEYSDD---------------------------DDLE-LQGAA------AAPIPNFF--
-S-DDDC--------LEDLPEKFDGNPDMLGPFMYQCQLFMEKS-TRDFSVDRIRVCFVT
SMLIGRAARWATAKLQRCTYLMHNYTAFMMELKHVFEDPQRREA--AKRKIRRLRQGPGP
VVDYSNAFQMIAQDLDWTEPALMDQFQEGLNPDIRAELS-RQEAPKTLAALITACIHIER
RLARDAA-----AKPDPSPRALVMPP-----NSQTDPTEPVGGAR----MRLSK-----E
E--------------------KERRRKMNLCLYCGNGGHFADTCPAKASKN--SPPGNSP
APL---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------NLLQRLREQEAQQDQIIQWLQRLSERLDALQQQ--PAAPTPASLPG
GGSSHTASAMYVFEPKVPFPEKFSGERSKFYAFQEACKLYLSFL-PRSFPMEELKVNFVM
TLLLGDPQLWAFSLP-PSDPARTSLDSFFKAMAIIYDDPDRSAS--ADSAIRNLRQGKRR
VEDYCTEFRRWAVETGWNDIALRSQFRIGLS DAVKDSLI-NFPASSSLDSLMYLAIQIDR
RHRERRQEKVSAASPQPSH--TEFIPRPEVAFSKPSE-EP---MQLGST-RLSS-----E
E---K----------------D-RRRAN GLCLYCGDKGHFRSTCPKRP------------
---------------------------------------------GNYTPMGNRLSDL--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVRGE---------------------------------------------------AGPA
SSPAQEKKEPPSGPLEEMEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAREEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHSMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----EQTGKRAC
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLTSRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDESNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNILALA------
----AILVLLR----------------VRQCLSVLPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGRW-QRNALHSQTHR
DLQFTPGFWMTLCEFFGVRVTPWEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTGA
SHPSRPR--HLMDPQVLEFLSSRLLHIRSADGQLHLLSREQA--VRALSQFLTLIYRQAL
PVPAWG-SQPREEARLEELPDED-EDA--DLD------

---------------------MIEPSEDSFETMMELKNPSSKQMESSEGSSNTVEETPGS
SGAQA--QAEAGSTT---------------------------------------------
--GPA--QEPPSGSVEETEELPTDLLQDM-------------------------------
------------------------------------------------------------
-----EKS----------------------SSGPCVKTEDPPNDLLQDLEESSSGRDDE-
------REDAPNVPIQDLEESC-DISH-------------------------EEEDDD--
------------------------------------------------------------
-------DEDPLS---EASDGLY-SVSANSSETPTDEDDETNLEDA----S-GEFGE--S
QPGSSPEEVMATMGSI-----------ISLFLRMQDVRQQQIVA----------------
----EEILTDAIDEGRLPSIRPFTGDRRDYHEFVVLCQMTMQNY-PAMFQNDHVRVKFFI
RHMTGLALEWANALMEQDSPLLNDFSAFIEAMSEKFEYRQTLRV--AEDAMFNIRQGNRT
VADYINEFQSLVPTLGWPDEVLQAHLCQGLNEDIRHYLF-RIPQPDCLENLMVLVLQIED
KLAERRAILRLPPESRPRN--MTWIDSPAP-------------EKWRVSSWLPY-----T
FHPDI----------------D-RAHIFLLLMVRVSPYH---SVAVQA------------
---------------------------------------------LLDSGAEGNYMDEKF
AQEHYVELYEK-------PYPQAIQ----TADGSLIGNEPTWLYTEPLMCVQQNHYEYIE
FDIVPSPH-----FSVVLGIKWLRTHAPDVDWIRGRCTFHSPYCLK--------NCFNPP
PPCIALEKYSVSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDRN-DV-YYECRSRAPWVSVTARMQEKA-------------RQQEEYWILY-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---R--DIKEADINYSVTRTE----D--------TWRATFGLTLHQMRCYRPFTMCSFAD
ESDNEIHFILKDILGFYVIARG-QEVLIYSMSQEEHFEHVRQVLLRFRSNNIYCSLDRSQ
FHRHTAEIMGFVLSPKGVKLN------KTLMNLIMGCPVPGSRRCLQTVIELVYPYRHFV
EQFAVIADPLVRQLLS-------SEPYYWGEEEQEAFECL--------------------
-----KRAFRKAPILYHPKPQNPFYLETG----VTGPFLYASLVQTD-----EETGKKAT
C-AF-------YSRRLS-------PMEVEYPQVELRILPIRASFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFHFDVMELPDDDD
TRAL---SQRRCLNQRAARGR---YMRPLLLLALRAGQRDSSPES---------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------EVQGILAAIPIERILNSFL----
----AHFSMAQIR---------------------TFVLHFFRSLIYWKNVLGVA------
----ALLAMMRV---------------R-QRLSPVPAPSWEVDRPQHR------HTLRLI
LDSSLIAGSGMATAIAQLFSQMPPLVGANTLPARELAEL--FLGPRCW-HWNAVHSRPRR
GLQFTPGFWLTLCEFFGVRVNPEEDIFPA-PHQHRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQDNDVQED----------------------------LLGDQE
--AVTYRPRNLLDPEVLDFLNNRLLYILGADGRLTLFSRNEV--ARTLARFLAMASRMVP
PSP------ARERARLEQLSDSSDDEL--D--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------M----YKNK
RVLKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQSQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREV--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSSRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MMEPSEDSFETMMERKNPSSKQMESSEGSSNTTVETPPG
GRVEA---------------------------------------------------AGLA
-----------SGLAQEMGEQSIDLRQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHREIKDPPNDLLQDL-----------
------------------EESCEGS-HLEEG-----------------------------
------------------------------------------------------------
---------GPFGGA---PGEMEE-EEDNPWESQEDQDYYTDLAESEEDE--SPEEP---
--DSSTVEVMGMVRSI-----------ISLYFRMQDLREQQRVA----------------
----EEILMNAINKGQLPNPKQFSGDRREYHEFIVLCQLILQSY-PRVFCNDRLRVGYII
SHLSGMAMEWAGDLLERESSVIDDFPAFLEAMNDTFEYRQALRV--AEDAMFNLRQGDRA
AIEYINEFQSLVPTLGWPDEVLQAHLCQGLKEDIRQYLF-RIPQPNSLENLITLVLQIED
KLAERRAILRLLPESRPRH--LTWLDSPVP-------------ERWTVSTWLPN-----E
FHPGI----------------K-RNHLFLLLLVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGATSNYMDEGF
AQEHYVELYQK-------PYAESVQ----TADGSLVGNEPVWLYTEPLVCLHQNHQESLE
FDIVASSK-----FSVVLGIKWLQLHAPEIDWVKGRCTFHSPYCLK--------NCFRPP
PPCIALEHHAVSLLPGLPH---------------------------QY------------
------------------------------------------------------------
----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDQSEET-FYDCASTAPWEPVGAGTQEKAK--------------QEEFWDPK-
----DML--------TSRHDY---------------------------------------
---------------------------------VQMIPELFDQLHG-ATWFTKLEL-R--
---G--TIVEESM--SIHQTE----D--------VWKVAFGLELQDMASYQPFLICADPI
IPQGVIHFILKDMIGLFVVSYG-QDVLVYSMSQEEHYHHVRQVLVRFRYHYVYCSLQRSQ
FHRHTAEFLGFVVTPKGVKLN------KSIVSTITGYPTPGSRKSLRNLMEFAFPYRHFV
ERFADITEPLVRQLQA-------DLPFYWGDEEQEAFVGL--------------------
-----KRAFRKAPLLYHPKPQNQFYLQTG----VTKTSLHASLIQMD-----KRTGKKVC
C-AF-------YSRNIS-------PMEVEASPAEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNKEDLA-----SLNNDRLTVLLPGHWVFFFTHFNFDVMEMPSSED
DQP---LPRRQRLGERAQQRRVATTTRP--------------------------------
-------TM----------------LVTMPAPT--------GD-----------------
-QS---------------------------------------------------------
-P------------ESED--EEESEGALHPDEPNGQNLQQGYLALIPVDQIFNSFL----
----AHFSMAQIR---------------------AVLLHFYRSLLFWKNLLAMA------
----ALLVMLR----------------FRRRLALLPAPAADPARPPQR------RSLRLF
LDASLLTSSGIATAVTQLFTQMPPLVGTNALPAEELAEL--FLGPGPWQLNA------LR
GLQMTPRFWQMLCQFFGIRGRALEGTQTH-PSPHQSLAPHVEGDEYVVLREALQ--DDLQ
RFRQCGLHDGLQDTSQDAQ---D------------------------------------D
VWALRPRQHLPTEAEVL----ARLTYIRSTQGGSVVIHRELT--ARDLIDFLASVYTQAL
PTLVEA-SPPREGATLEELPSDADEDA--GLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CRNK
RVLKTKR-RR------------GARGGQDPGLHPHRSEE---------------------
-AA--GS----S-PVAMGPDCPP-------------------------------------
-------------KPSGHKS--PCVPNMTERRRDELSEEINNLREKVIR-----------
---QSEENSQLQSQV---QKLTEENSTLRE------------------------QVEPPA
AEEEAEE---------------------------DELE-LRGAA------AAAAPPPP--
-VE-EEC--------PEDLPEKFDGNPDMLAPFISQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VVDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALISQCIQIER
RLARAA----AARKPRSPPRALVLPNVSGN--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SPAGNSP
APL---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVRGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLQEMEELRTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDL-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAREEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFYNDRLRVGYVI
SHLSGLALEWAKALLQENSPLIGDFPAFLEAMSEVFEYRQALRV--AEEAMFTIRQGGRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPDI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGAGMQERARL-------------QEEYWDLQ-
----DML--------TNRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AEWFTKLEL-R--
---G--TIVEESV--NGHRTE----D--------VWKAAFGLELEEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFFVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSKLSLRNFIEFVFPYRHFV
ERFSVIAEPLVRQLLS-------SYQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTGTALHASLIQID-----DQTGKRAC
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFTVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PS---------------------------------------------------------
-T------------ESG---EEENEE---QDESNEQTLRQELLAMIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSLRPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALVGANTIPAQELAEL--FLGPGRW-QRNALHSQAHR
GLQFTPGFWLTLCEFFGVRVTPQEGHLPA-LRQNRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTAA
THPPRPR--HLMDPQVLEFLGSRLLHIRSADGQLHLLSREQA--ARALSQFLTLIYRRAL
PIPAWE-SQPREQARLEELPDED-EDA--DLD------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVRGE---------------------------------------------------AGPA
SSPAQEKKEPPSGPLEEMEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAREEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHSMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----DQTGKRAC
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRA---LPPVRNLRWR-AF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDESNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSVLPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGRW-QRNALHSQTHR
GLQFTPGFWMTLCEFFGVRVTPSEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTGA
SHPPRPR--HLMDPQVLEFLSSRLLHIRSADGQLHLLSREQA--VRALSQFLTLIYRQAL
PVPALG-SQPREEARLEELPDED-EDA--DLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MVNK
RVLKTKK-RR------------SGRGGQDPGLHPHRSEV---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIIFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPFYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSESDMAALRDFVA-----
------RNVKDGLITPTVAPNGAQILQ----VKRGWKLQVS--YD-CRAPNNM--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YATYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

---------------------MIEPSEDSFETMMERKNPSSKQMESSEGSSNTTVETSGS
GAQEA---------------------------------------------------AGPA
S-----------GPAQGMKELPIDLRQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHREIKDPPNDLLQDL-----------
------------------EESRNGS-HQEVG-----------------------------
------------------------------------------------------------
---------DPSGEA---PGTTEE-ASVNPRGARNKHGSDTDLASGREEE--EQLEE---
--EPETSEFMATVRSI-----------ISLYFRMQDLREQQRVA----------------
----EEILMEAINAGRLPVPVNFSGDRREYHEFIVLCQLILQSY-PSMFYNDRLRVGYIM
CHLSGMALEWARALMNENSSLMSDFPAFLEAMSGMFEYRQAQRV--AEDAMFNIRQGSRT
AIEYINEFQGLVPTLGWSDEVLQAHLCQGLN EEIRHYLF-RVPQPDSLESLIVLVLQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPC-----D
ARPAI----------------D-RNHLFLLLLVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGAGGNFMDERF
AQEHYVELYEK-------PYPQMVQ----GVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVILGIKWLRIHTPEVDWVRGRCTFHSPYCLQ--------KCFRPP
PPCIALERHAISLLPGLPP---------------------------LY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSIAPWEPVGAGMQESARP-------------RDDNWNAE-
----SML--------TDKQDY---------------------------------------
---------------------------------IQIIPELFDQLHG-ATWFTKLEL-R--
---G--TIVEESM--NIHQAE----D--------VWKTAFGFELPKMKSYKPFPLSSDPV
IPQNVLHFILKDMLGYFVLSYG-QDVVVYSMSQEEHFQHVRQVLVRFRHHHVYCSLDRSQ
FHRHTVEFMGFVLTPKGVKLN------KTIVTTVTGYPTPGSKKSLKHLLRFILPYQHFV
ERFSVIIEPLVRLLLN-------APTFSWGDEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTKTALHASLIQID-----EQTGKRVS
C-AF-------YSRIIS-------PIEVAYSQLEMKILPIRASFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMERPAQEG
GRP---LPPVRNLTRRAF--QHNTATRS--------------------------------
-------RS----------------LFTTGGYF--------GD-----------------
-RS---------------------------------------------------------
-L------------DSEE--DDETEDASNQDEPNGRNLQQEFLALIPIDQIFHSF-L---
----AHFSVAQIR---------------------AVILHFFRGLLFWKDTLAVA------
----ALLVLLK----------------LKRRLSMLPTPAWAAVRPPQR------RWLRLG
QAATLVPGSGTATAIAQLLTQVPPTVGTSAVPAQELAGL--LLGPGHRQ-QRALLPLTRR
GLQLTPGFWLLLCDFFGVRVGAWEGARPL-PGGTRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDEQENDVQEA-----------------------------LSTDT
PMVLQPLRHLPVPSEVLAFLSRHPPRVRSAYGQPDPVAQELA--ARALLRFLTTVYAQAP
PAPIWA-GQPRGEARLEELPDGEDN-A--SLK------

------------------------------------------------------------
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---------------------------LAERRRDDLSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTSLRE------------------------QVEPTP
Q---DEE---------------------------DDIE-LRGAA------AAAAPAAP--
-LE-EEC--------PDDLPEKFDGNPDMLVPFMAQCQLFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMTEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLS DHIQAELS-RLEVAKSLSALIGQCIHIER
RLARAA----AARKPRSPPRALVLPHITS--HHQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKL NLCLYCGNGGHYADNCPAKASKA--SPAGNSP
APL---------------------------------------------------------
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------------MAAAGGSSNCP-----------------------PPPPPPPPNNNNNN
NNTPK-----------SPGV--PDAEDDDERRHEELPEDINNFD-DMNR-----------
---QFE-NMNLLDQV---ELLAQSYSLLDH---------LDDFDDDDEDDDFDPEPDQDE
LPEYSDE---------------------------DDLE-LQGAA------AAPIPNFF--
-S-DDDC--------LEDLPEKFDGNPDMLGPFMYQCQLFMEKS-TRDFSVDRIRVCFVT
SMLIGRAARWATAKLQRCTYLMHNYTAFMMELKHVFEDPQRREA--AKRKIRRLRQGPGP
VVDYSNAFQMIAQDLDWTEPALMDQFQEGLNPDIRAELS-RQEAPKTLAALITACIHIER
RLARDAA-----AKPDPSPRALVMPP-----NSQTDPTEPVGDPH----QDPHH-----H
P--------------------NQDP-------------------PQDPPPQ--DPPHQDP
PPQDPPHQDPPHQDPPHQDPPHQDPPHQDPPQHQDPPH--------------------QD
PPQHQDPPQHQ-------D---------------PPHQDPPQHQDPH---------QDPH
QDAHQDPH-----------------QDPHLHQH--------QHPHQHP----------QM
HPHGH-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------PN---------------------APQQPPFFYHMA-GFRI---YHPVRYY
YIQNVYTPVDEHV-YPGHRVVDPNIEMIPGAHSLPSGHLYSMSESEMNALRNFVD-----
------RNVKDGLMTPTVAPNGAQVLQ----VKRGWKLQVT--YN-CRAPQSG--TIQNQ
YLRMSLPNMGDP-----AHLASY----GEFV-QVPGYP-YPA------------------
----------------YVYYTGPQMMTAWYPVGRDVHGRI-----IVVPVVITWSQNTHR
----------QPPVPQYPPPQPPPPPPPPPPPPPPPPASSCSAA----------------
------------------------------------------------------------
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--------------------------------------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVRGE---------------------------------------------------AGPA
SSPAQEKKEPPSGPLEEMEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAREEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHSMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----EQTGKRAC
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRV---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLTSRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDESNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNILALA------
----AILVLLR----------------VRQCLSVLPAPAMQVARPRPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGRW-QRNALHSQTHR
DLQFTPGFWMTLCEFFGVRVTPWEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTGA
SHPSRPR--HLMDPQVLEFLSSRLLHIRSADGQLHLLSREQA--VRALSQFLTLIYRQAL
PVPAWG-SQPREEARLEELPDED-EDA--DLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------M----YKNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYSVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----AEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------KLPTFLAQVELYFSQLSAHAYPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNNFKKLLTDTFGDPLHTEN--AGWALYRLKQGKGT
VLDYLNKFNLYHHQLDWGENAFMLLFTAGLSDYLQDELA-RLEPAENWDALVAKVLRLDA
RFESRKHSKAMCAPPMH-------V---TRAPVVMGE-EP---MELGVFKKLST-----E
E---K----------------N-RRRQLGLCLYCGNAGHFAKNCNVKP------------
---------------------------------------------SQLSGKEHMTLEK--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MVNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIR-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHVASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAQQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MLNKRALKSKR-
---RR--------SHNGHKS--PCVPNLTERRRNELSEEINNLRDKVIR-----------
---QTEQNNQLHDQV---QKLTEENSTLRE------------------------QVES--
-T-EEEE---------------------------DDLA-LCGAA------AAAAPPPP--
-VE-EEC--------LEDLPEKFDGNPDTLTPFMSQCQVFMERS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERAHYLMHNYPAFMLELKHVFEDPQRREA--ARRKIRRLRQGLGS
VVDYAHAFQMIAQDLDWNEPALIDQFHEGLNSRIQEELV-HMEAAESLSSELH----MD-
--------------------------------------------------KTLA-----E
K--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKA--SP-----
----GPPATGPEATRSPPDDA-SSPHLQVTLHIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRVK-------DWPILVE----AIDGRPIASGPVVHETHALVVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRP------YTPI
PRALP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PGPPPALYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLADPHLEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNSF--TIQNQ
YPRLSIPNLDDQ-----AHLATY----TEFVPQVPGYQTYPT------------------
----------------YTTYPTYPVGFAWYPVGRDAQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTM---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMERKNPSSKQMESSEGSSETTVETPPG
GRAEA---------------------------------------------------AGLA
-----------GGLAQETGEQSIDLRQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHREIKDPPNDLLQDL-----------
------------------EESCEGS-HLEEG-----------------------------
------------------------------------------------------------
---------GPFGGA---PGGMEEEEEDNPWESQEDQDYYTDLAESEEDE--SPEEP---
--DSSTVEVMGMVRSI-----------ISLYFRMQDLREQQRVA----------------
----EEILMNAINKGQLPTPKQFSGDRREYHEFIVLCQLILQSY-PRVFCNDRLRVGYVI
SHLSGMAMEWASDLVEKESSMIDDFPAFLEAMNDTFEYRQALRV--AEDAMFNLRQGDRA
AIEYINEFQSLVPTLGWPDEVLQAHLCQGLKEDIRQYLF-SIPQPNSLENLIALVLQIED
KLAERRAMLRLPPEARPRH--LTWLDSPVP-------------ERWTVSTWLPN-----E
FHPGI----------------K-RKHLFLLLLVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGATSNYMDEGF
AQEHYVELYQK-------PYTELVQ----SADGSLIGNEPVWLYTEPLVCLHQNHQESLE
FDIVASSK-----FSVILGIKWLQLHAPDIDWVKGRCTFHSPYCLK--------NCFRPP
PPCIALEHHAVSLLPGLPH---------------------------QY------------
------------------------------------------------------------
----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDQSEET-FYDCASTAPWEPVGAGVQEKAK--------------QEEFWDLQ-
----DML--------TSRHDY---------------------------------------
---------------------------------IQMIPELFDQLHG-ATWFTKLEL-R--
---G--TIVEESM--DIHQTE----D--------VWRVAFGLELQEMASYQPFLICADPI
ISQGVIHFILKDMIGLFVISYG-QDVLVYSMSQEEHYHHVRQVLVRFRYHHVYCSLQRSQ
FHRHTAEFLGFVVTPKGVRLN------KSIVSTITGYPTPGSRKSLRNLLEFAFPYRHFV
ERFADITEPLVRQLRA-------DQPFYWGDEEQEAFVGL--------------------
-----KRAFRKAPLLYHPKPQNQFYLQTG----VTKTSLYASLIQMD-----KRTGKKAC
C-AF-------YSRNIS-------PMEVEASPAEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNKEDLA-----SLNNDRLTVLLPGHWVFFFAHFNFDVKEMPTSED
AQP---LPRRQRLRKRVQQRQAATTTRP--------------------------------
-------TM----------------LVTMRAPP--------GG-----------------
-QS---------------------------------------------------------
-P------------ESED--EEESEDALHPDESNGQNLQQGFLALIPVDQIFSSFL----
----AHFSMAQIR---------------------AVMLHFYRSLLLWKNLLAMA------
----ALLVMLR----------------FRRRLALLPAPAADPARPPPQ------RSLRLF
LDASLLTSSGIASAITQLFTQMPPLVGTNALPPEELAEL--FLGPRPWQLHA------LQ
GLQITPRFWQMLCQFFGIGGPALEGTQTH-PSPR--LVPHVEGDDCVVLRDALQ--DDLQ
RFRQCGLHDGLQDTSQDAQDAQG------------------------------------G
AWARRPLQHPPTQAEAL----ARLADIRSTQGLSIVTHRELM--ARALTDFLAAVSTQAL
PTLVEA-SPPSERATLEELPSDSDEDA--DLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MRNK
RVLKTKR-RR------------GARGGQDPGLHPQRSEV---------------------
---AAGRSPPTP-IIIMGPADCP-----------------------PPPPPPPPHNNNN-
---ND--------KHSGHKS--PCVPNMTERRRDELSEEINNLREKVIR-----------
---QSEENNNLQSQV---QKLTEENTTLRE------------------------QVEVEP
TP-EDED---------------------------DDLE-LRGAA------AAAAPPPP--
-ID-EEC--------PEDLPEKFDGNPDMLAPFMTQCQIFMEKS-TRDFSIDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VVDYSNAFQMIAQDLDWNEPALIDQFHEGLNDRIQEELS-HLEVPKTLSALIGQCIHIER
RLARAAAAAAAARKPRSPPRALVLQHPPGH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADSCPAKASKS--SPGKLPG
PAVEGPSATGPEIIRSPQDDAVSSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPIRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLADHREVIS
FDVTQSPF-----FPIVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCQM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PTPQPSLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPNIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEYVPQVPGYQTYPT------------------
----------------YTTYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTM---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------RNK
RVLKTKQPRR------------RGARGQDPGLHPHRCEA---------------------
---TPGRSPPTP-IVAMGSADCP-----------------------PPPPPPPPNNNNN-
--------------NKGNQS--PCVPNMTERRRDELSEEINNLREKVIR-----------
---QSEENNNLQSQV---QKLTEENSTLRE------------------------QVEVEP
VP-EDDE---------------------------DDIE-LQGAA------AAAVPTTP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMEKS-TRDFSLDRVRVCFVT
SMMTGRAARWASAKLERSNYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGLGS
VVDYSNAFQMIAQDLDWNEPALIDQYHEGLSDQIQEELS-HIEAPKTLSALIGQCIHIER
RLARAA----AARKPRSPPRALVLPN--AG--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKN--SP-----
----GPSATGPELIRSPQDDAVSAPHLQVMLQIHLPGRHALFVRAMIDSGASGNFIDQEY
VIQNAIPVRVK-------DWPILVE----AIDGRPVASGPIVHETHHLFVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLTIHDPNITWSTRSIVFDSDYCRYHCRM------YSAI
PPPLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------PP---------------------PGPHPTLYFPVEGGYRV---YHPVRYY
YVQNVYTPVDHHH-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVT--YN-CRAPNHV--TIQHQ
YPRLSIPNLEDQ-----AHLATY----TEYVPQVHGYHSYPT------------------
----------------Y-AYPTYPVGFAWYPVGRDGHGRS-----LYVPVMVTWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPPSSSYTM-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MGLAGCP-----------------------PPPPPPPPNNNNN-
---NN--------KPSGHKS--ACVPNSTERRRDELSEEINNLREVVIR-----------
---QSEENSNLQSQV---QKLTEENSTLRE------------------------QVEPTP
---EDDE---------------------------DDIE-LQGAA------AAAVPSTQ--
-TEEDCP--------EEDLPEKFDGNPDMLAAFMSQCQTFMERS-TRDFSLDRVRVCFVT
SMMTGRAARWASAKLERAHYLMHNYPAFMMELKHIFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-RLEVAKSLSALIGQCIHIER
RLVRAAAA--AARKPRSPPRALVLAH--HH--HHHDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKS--SPAGNSP
APL---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------EPSSGQHSEIKDPPNDLLQDL-----------
------------------EESCKAS-RQEVG-----------------------------
------------------------------------------------------------
---------DPIGEA---PGEMEE-ASVNE-GELDEEDDDTDLSEDEEEE----------
EEEPGELELRGRVSSF-----------TSMYFWMQDLKEQQKIA----------------
----IEILMKAIRIGRVPEPQIFSGDRRDYPEFFVHCHMIIQGY-PRKFRNDRRRVRFVI
SHLSDTALEWAQNLKRQRSPLLTNYPAFMEAMTNMFHYKEELRV--AEDTMLNITQGDRA
AIDYIDEFRELVPTLGWPDEVLQAHLCLGLNEEIRQYLF-QLPQPDSLDSLMALVLQIEE
NLAERKAMLRMRPETHSRN--LAKMDSPAP-------------EKWPVSSWLTY-----E
IQPDI----------------D-RRHVFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGASSNFMDEKF
AQEHYVELFEK-------PYPQSIH----TMDGSLIGNEPVWLHTEPLVCFHQNHHELIE
FDIVPSPN-----FSVVLGINWLRVHSPDIDWARGRCTFHSPYCLK--------NCFSPL
PPSTTLERHAISLLPGLLP---------------------------QY------------
------------------------------------------------------------
----SDLADVFNPKKADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-NT-ADTCPSVAPPEPVGAGMQETARL------------GNE-------
------E--------EESQED---------------------------------------
---------------------------------KQIIPELFQQLHG-ATWFTRLEL-R--
---G--SIVEEGK--K-KAAE----E--------LWKVAFGLELQKKTSYQPFEICSDPL
IPQSVMHCILKDLLGKCVLSYG-NEVVIYSMSQEAHLRHIRQVLVRFRHHHVYCSLDRSQ
FHQHTVEFMGFVLTPKGVRLN------KSVVKTIRDYPIPLSKESLQNLMELMSPYCHFV
ERFAAITEPLRRQLLT-------TNPFHWGDEEQEAFESV--------------------
-----KRAFRKAPLLHHPKRHKQFYLDTG----VNMTALYASLMQVD-----EQTGKRVF
C-AF-------FSRDLS-------PEEANSSPLMMKTIAIKAALDVWSCYLES-------
------TEEPIMILLNTEDLA-----SLNNDRLTVILPGQWAKFFGRFHCDVMERPEQDG
SSSLPLQNPNRGPLRAHIATRARTATRAHTTHTATRARTATRAHTATQARTATQARTDTQ
THTATRARTATRARTATRARTATRALTDTRALTDTRARTDTRARTDTQTHTATRARTDTR
ART-DTRARTDTRAHTATRAH----------------------------TDTRAHTDTWP
LTDTRARTDTRARTDTDQLPELGEQKENEHEGPSRQSQQQEALTPLQMDQILSNLL----
----GHLNMDQMR---------------------SLFLHFFRDLHISQEALAPM------
----AVLAILK----------------MKQHLPLLPAPTLQVALLPAT------RSLRLI
LDSSLLTNRGIATAITQLLTQMPPLVGTVTSGLRNRP-------------NRGPCCPGRR
LLPLPSEFWTMLCERFCVRVAPRERSQPLLQGRSHYLELHVIGS-DVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQAEDDVQDDGAQGVQEEE-----------ANEGG--------
------------DEEIEDQILYR--QLYGDRDQPNLPHQDPA--ARSLAHFLAMICAEDP
-VPL-RGRQARGGARLEELPEDDEDSD-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MRNK
KLLKTKR-RK------------GGRGGQDPGLHPHRSEA---------------------
---APGRSPPTP-TLTLGPDCPP-----------------------PPPPPPPNGPSSS-
SSSCSSSSSSSSSSRSGQRG--QYIPNLAERRRDDLSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTSLRE------------------------QVEPAP
Q---DEE---------------------------DDLE-LRGAA------AAAAPPTP--
-IE-EEC--------PDDLPEKFDGNPDMLVPFMAQCQLFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMTEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQAELS-RLEVAKSLSALIGQCIHIER
RLARAA----AARKPRSPPRALVLPHITS--HHQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKA--SPAGNSP
APL---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------FDGFRNKLPTFLAQIELYFSQISAQAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNDFKKLLSDTFGDPLRMEN--ASWALYRLKQGKGS
VLDYLNKFNSYRHQLDWGENAFMLLFIAGLNDYLQDELA-RLEPAENWDALVAKVLRLDA
RFESRKQSRAMYAPAVS-------A---PRAPVAKGE-EP---MELGVFRKLST-----A
E---K----------------D-RRRQFGLCLYCGNAGHFARNCNVNA------------
---------------------------------------------FPAFGKR--QECF--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MATGGFDCP-----------------------PPPPPPPPNNNNNN
NK---------------PKS--PCVPNNNQRRRRRHG-EISGES-SGFR-----EQQV--
-VRPTMRNNSLHTQV---EL----------------------FP----------GHNGSF
GNFEDND---------------------------DDLA-LQGAA------AAAAPTIF--
-FD-DDC--------LEFLPEKFDGNPDNLNYFIAQCQTFMERS-NRDFSADRIRVCFVT
SMLTGRAARWASIKLERASYLMNNYRAFMMELKQVFEDPQRREA--AKRKIRRLRQGLGS
VAEYANSFQMVAQDLDWNEHALIDQFLEGLSDEIREEVS-RHELPDTLSALISLSIHIER
RQARAA----AAPRPDPP-RALVMPQ-----NRQSDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGSGGHYADNCPAKASKN--SPSGNS-
---PGPSATGPDRIRSPPPEA-STPHLQVMLQIHIPGRHTLFVRAMIDSGASGNFIDQDF
VIQNGIPLRIK-------EWPIMVE----AIDGHPIASGPIVLETHHLIVDLGDHRELLS
FDVTQSPF-----FPIVLGIRWLSTHDPHITWSTRSIVFNSDYCRFRCRV------YSQI
PPALLLP-PYP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------PHPPFFYHVD-GYRVFH---PVRYY
YVQNVYTPVDEHV-YPGHRLVDPHIEMIPGAHSIPSGHVYSLSESEMAALREFVD-----
------RNVKNGLMIPTVAPNGAQVLQ----VKRGWKLQVT--YN-CRAPHNC--TVQNQ
YVRMTLPNMADH-----AHLATY----GEFVPHIHG----------------------YH
HHHHHI---------PVYAYAGHQVMFAWHPVGRDIHGRM-----ILTPVVITWCPHWYR
HH--------PHPVPQYPPPPPPPPPPPPPPPPPPPPPSYSTL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MMEPSEDSFETMMELKNPSSKQMESSEGSSNTAEETPGT
SGAQAQAQAEAGSAS---------------------------------------------
--GPA--QEPPSGLVQETEELPTDLLQDM-------------------------------
------------------------------------------------------------
-----EKS----------------------SSGPCVKTEDPPNDLLQDLEESSSGRCDE-
------TEDAPNVPFQDLEESC-DISH-------------------------AEED----
------------------------------------------------------------
-------GEDPLS---EISDGLC-VVSSNSSETRSDED-DTNLDVT----S-GEFGE-ES
QAGNSPEEVVATMGSI-----------ISLFLRMQDVRQQQIVA----------------
----EELLTDAIDDGQLPSIRPFSGDRRDYHEFIVLCQMALQNH-QAMFPTDQLRVRFLI
RHMTDLALEWATTLIEQESPLLNNFSAFLQAMSDRFEYRQTLRV--AEDAIFSIRQGNRS
VADYINEFQSLVPTLRWPDEVLQAHLCQGLNEDIRHYLF-RIPQPESLENLMVLVLQIED
KLAERRAVLRLPPESRPRN--MTWIDSPAP-------------EKWRVSSWLPY-----T
LHPDI----------------D-HAHIFLLLMVRVSPYH---SVAVQA------------
---------------------------------------------LLDSGAEGNYMDERF
AQEHYVELYER-------PYPQAIQ----TADGSLIGNEPTWLYTERLLCVQQNHYEYIE
FDIVPSPH-----FSVVLGIKWLRTHAPDVDWIKGRCTFHSPYCLR--------NCFTPP
PPCIALERYGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDRN-DV-FYECRSRAPWASVTARMQEKA-------------RQQEEYWILC-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLVL-S--
---R--DIKGADINYSVTRTE----D--------TWRATFGLTLHQMRCYRPFTMCSFAD
ESDNEIHFILKDILGFYVIARG-QEVLVYSMSQEEHVEHVRQVLLRFRNNNVYCSLDRSQ
FHGQTAEIMGFVLSPKGVKLN------KTLMNLIMGCRVPGNRRCLQTIIELVYPYRHFV
EHFAIIADPLVRQLLS-------SEPYYWGEEEQEALECL--------------------
-----KRAFRKAHTLYHPKPQNPFYLETG----VTGSFLHASLVQTD-----EETGKKAT
C-AF-------YSRRLS-------PMEVEYPQVELRILPIRASFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFHFDVMELPDEDD
TLAL---SQRRSWNDRAARGR---IMRPLLLLALRRGRRDTSAESDSDVEPQSE--SESR
------------------------------------------------------SRSDTE
I-----------------------------------------------------------
-----------------ESEDSEYGSYQESEDYSQQTLVQQLLSAIPINQLFSGIL----
----AHFSMAQIR---------------------VVIHSFYRGLIYWKNALGVA------
----SLLAMMRV---------------R-QRQCPVPTPSWEVERPQPR------QTVRLI
LDSSLIAGSGMSAAIAQLFNQMPSLAGANTLPSRELAEV--FLTPGGW-HQNAVNFRPRR
DLQFTPGYWLTLCEFFGVRVNPDDDIFPA-PIRHRCLELRVIGDEDVVLREALQ--DDLQ
RYRQSGLHDGLQDTSQDAQGNDVQ-D----------------------------LLGDQE
--VVTLRPRNLLDPQVLDFLNNRLLYILGADGQLTLATRDEV--ARTLARFLVIASRTVP
PSP------PRDQARLQQLSDSSDDEL--E--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PERFDGSRNKLPTFLAQIELYFSQISAQAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLDDFKKLLSDTFGDPLRMEN--ASWALYRLKQGKGS
VLDYLNKFNSFRHQLDWGENAFMLLFIAGLNDYLQDELA-RLKPAENWDALVAKVLRLDA
RFESRKQSRAMYAPSVS-------A---PRAPVAKGE-EP---MELGVFRKLST-----A
E---K----------------D-RRRQLGLCLYCGTAGHFARNCNVKP------------
---------------------------------------------SQLSGKVNPQARM--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MRNK
RVLKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQSQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREV--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SPAGNSP
APL---------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

---------------------MMEPSEDSFETMMELKNPSSKQMESSEGSSNTAEETPGT
SGAQAQAQAEAGSAS---------------------------------------------
--GPA--QEPPSGLVQETEELPTDLLQDM-------------------------------
------------------------------------------------------------
-----EKS----------------------SSGPCVKTEDPPNDLLQDLEESSSGRCDE-
------TEDAPNVPFQDLEESC-DISH-------------------------AEED----
------------------------------------------------------------
-------GEDPLS---EISDGLC-VVSSNSSETRSDED-DTNLDVT----S-GEFGE-ES
QAGNSPEEVVATMGSI-----------ISLFLRMQDVRQQQIVA----------------
----EELLTDAIDDGQLPSIRPFSGDRRDYHEFIVLCQMALQNH-QAMFPTDQLRVRFLI
RHMTDLALEWATTLIEQESPLLNNFSAFLQAMSDRFEYRQTLRV--AEDAIFSIRQGNRS
VADYINEFQSLVPTLRWPDEVLQAHLCQGLNEDIRHYLF-RIPQPESLENLMVLVLQIED
KLAERRAVLRLPPESRPRN--MTWIDSPAP-------------EKWRVS-----------
---NI----------------D-HAHIFLLLMVRVSPYH---SVAVQA------------
---------------------------------------------LLDSGAEGNYMDERF
AQEHYVELYER-------PYPQAIQ----TADGSLIGNEPTWLYTERLLCVQQNHYEYIE
FDIVPSPH-----FSVVLGIKWLRTHAPDVDWIKGRCTFHSPYCLR--------NCFTPP
PPCIALERYGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDRN-DV-FYECRSRAPWASVTARMQEKA-------------RQQEEYWILC-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLVL-S--
---R--DIKGADINYSVTRTE----D--------TWRATFGLTLHQMRCYRPFTMCSFAD
ESDNEIHFILKDILGFYVIARG-QEVLVYSMSQEEHVEHVRQVLLRFRNNNVYCSLDRSQ
FHRQTAEIMGFVLSPKGVKLN------KTLMNLIMGCRVPGNRRCLQTIIELVYPYRHFV
EHFAIIADPLVRQLLS-------SEPYYWGEEEQEALECL--------------------
-----KRAFRKAHTLYHPKPQNPFYLETG----VTGSFLHASLVQTD-----EETGKKAT
C-AF-------YSRRLS-------PMEVEYPQVELRILPIRASFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFHFDVMELPDEDD
TLAL---SQRRSWNDRAARGR---IMRPLLLLALRRGRRDTSAESDSDVEPQSE--SESR
------------------------------------------------------SRSDTE
I-----------------------------------------------------------
-----------------ESEDSEYGSYQESEDYSQQTLVQQLLSAIPINQLFSGIL----
----AHFSMAQIR---------------------VVIHSFYRGLIYWKNALGVA------
----SLLAMMRV---------------R-QRQCPVPTPSWEVERPQPR------QTVRLI
LDSSLIAGSGMSAAIAQLFNQMPSLAGANTLPSRELAEV--FLTPGGW-HQNAVNFRPRR
DLQFTPGYWLTLCEFFGVRVNPDDDIFPA-PIRHRCLELRVIGDEDVVLREALQ--DDLQ
RYRQSGLHDGLQDTSQDAQGNDVQ-D----------------------------LLGDQE
--VVTLRPRNLLDPQVLDFLNNRLLYILGADGQLTLATRDEV--ARTLARFLVIASRTVP
PSP------PRDQARLQQLSDSSDDEL--E--------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVRGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLQEMEELPTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDL-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAREEQEAHTDLKESGREE--TPQEE-QN
QTEHSAAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFYNDRLRVGYVI
NHLSGLALEWAKALLQENSPLIGDFPAFLEAMSEVFEYRQALRV--AEEAMFTIRQGGRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPDI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FHECPSTAPWEPVGAGMQERAGL-------------QEEYWDLQ-
----DML--------TNRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AEWFTKLEL-R--
---G--TIVEESV--NGHRTE----D--------VWKAAFGLELEEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFFVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSKLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SYQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTGTALHASLIQID-----DQTGKRAC
C-AF-------YSRNIS-------PIEVEYSRAEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PS---------------------------------------------------------
-T------------ESG---EEENEE---QDEPNEQTLRQELLAMIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFQGLLYWKNTLALA------
----AILVLLR----------------VRQCLSLRPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALVGANTIPAQELAEL--FLGPGRW-QRNALHSQAHR
GLQFTPGFWLTLCEFFGVRVTPQEGHLPA-LRQNRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTAA
THPPRPR--HLMDPQVLEFLGSRLLHIRSADGQLHLLSREQA--ARALSQFLTLIYRRAL
PIPAWE-SQPREQARLEELPDED-EDA--DLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MRNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SPGKLPG
PAVEGPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
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----------------------------KLPTFLAQIELYFSQISAQAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLDDFKKLLSDTFGDPLRMEN--ASCALYRLKQGKGS
VLDYLNKFNSFRHQLDWGENAFMLLFIAGLNDYLQDELA-RLEPAENWDALVANVLRLDA
RFESRKQSRAMYAPSVS-------A---PRAPVAKGE-EP---MELGVFRKLST-----A
E---K----------------D-RRRQLGLCLYCGTAGHFARNCNVKP------------
---------------------------------------------SQLSGKGNREANR--
------------------------------------------------------------
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------------------------------------------------------------
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----------------------FDGTRCKLPTFLAQVELYFSQLSAHAFPTDTSKVAFIL
SLLTVPAGQWATNLILGNDPVKDNLNNFKKLLTDTFGDPLRTEN--AGWALYRLKQGKGT
VLDYLNKFNLYRHQLDWGENAFMLLFTAGLSDMLQDELA-RLEPAESWDALVAKVLRLDA
RFEARKHSKAMCAPPMH-------V---TRAPVVMGE-EP---MELGVFKKLST-----E
E---K----------------S-RRRQLGLCLYCGNAGHFAKNCNVKP------------
---------------------------------------------SQLSGKXGILRACL-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

---------------------MIEPSEDSFETMMERKNPSSKQMESSEGSSNTTVETSGS
GAREA---------------------------------------------------EGPA
R-----------GPAQEIKELPIDLRQDME------------------------------
------------------------------------------------------------
----------------------------GPSSGPRREIKDPPNDLLQDL-----------
------------------EESRNGA-RQEVG-----------------------------
------------------------------------------------------------
---------DPSSEA---PGGMEG-ASDDPWGAQDEEADDTDLASARE-E--GPLEE---
--DSETSEFMATVRSI-----------ISLYLRMQDLREQQRVA----------------
----EEILMKGIHAGQLPVPSRFSGDRREYHEFIVLCQLILQSY-PRMFCNDRLRVGYVI
CHLSGMALEWATALVQEGSPLIDDFPAFLEAMSGMFE YRQALRV--AEDAMFNIRQGTRT
ATEYINEFQGLVPTLGWSDEVLQAHLCQGLNEEIRHYLF-RVPQPGSLDSLIALVLQIEE
KLAERRAMLRLPPEARPRN--PTWVDSPAP-------------ERWMVSSWLSR-----D
RRPVI----------------S-RDHLFMLLLIRVNPYH---SV AVQA------------
---------------------------------------------LVDSGAGGNYMDERF
AQEHYVELYEK-------PYPQMVQ----SVDGSLVGNEPVWLHTEPLVCIHQNHQEPIE
FDIVPSPN-----FSVILGVNWLRTHSPEVDWIKGRCTFHSPYCLQ--------KCFRPP
PPCIALERHAISLLPGLPP---------------------------LY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSIAPWEPVGARVQESARP-------------RDEYWDPQ-
----DML--------TNRQDY---------------------------------------
---------------------------------VQMIPELFDQLHG-ATWFTKLEL-R--
---G--TIVEESA--SIRQAE----D--------VWRTAFGFEPQETESYQPFPLSSDPT
IPQDVVHFILKDMLGYFVLSYG-QDVLIYSMSQEEHFQHVRQVLVRFRHHRVYCSLDRSQ
FHRHTVEFLGFVITPKGVKLN------KRIVTTVTGYPTPGSKKSLQHLIEFIFPYRHFV
ERFTTIAEPLARQLLT-------SDAFSWGDEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----ATKTALHASLVQID-----DQTGKRVS
C-AF-------YSRNIS-------AIEVAYSQLEMKILPIRAAFTVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFHFDVMERPEQDG
GRP---LPPARNLNRRPF--RRNTAARA--------------------------------
-------RP----------------PFATGGKP--------CP-----------------
-SL---------------------------------------------------------
-T------------PRVL--QAL-----------RRHAGLTFCALTGPHPSIHPRHLPLI
AAPRDHGQDPQVQSQGLSDLDPAGPLGGLKAHRRSARHSQHSGLLS-STAAPVR------
----GLLRSLH----------------QDKRRGT------KAQRGQAT-----CWWLQKS
Q-ERTKP-----------------------------------------------------
------------------------GLGTL-PGGLCSVTVGCS---TPAV-----------
PTALCHCHGALRQPPQT---ADIM------------------------------------
----VP------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMELKNPSSKQMESSEG-----------
----------------------------------------------------------PA
SGPAREGEEPPSGPLQEMEELPIDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHKETEDPPNDLLQDP-----------
------------------EESCNGDSHQALE-----------------------------
------------------------------------------------------------
---------DPLTEV---SEETEG-VAVSPLETQEDQEDTTDLKDSEDED--SPEEE--S
QVEPSPAEMLAMMRSI-----------VSLFFRMHDLNEQQRVA----------------
----EEILVKGIDAGQLPTPRCFSGDRREYREFIVLCQLILQTY-PRMFYSDHLRVRYVI
SHLSGLALEWAQSLIQQNSPVLGDFPAFLEAMSEVFE YRHTLRV--AEDAMFNIRQGDRC
ATDYINEFQSLVPTLRWPDEVLQAHLCQGLNEDIRHYLF-RVPQPDSLDSLVVLILQIED
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWSVSSWLPT-----D
FHPGL----------------Q-RAHLFLLLLVRVT PYH---SVAVQA------------
---------------------------------------------LVDSGAEGNFMDEKF
AQEHYIELYEK-------PYPQMIQ----TVDGSLIGNEPIWLYTERLVCIHQNHQEAIE
FDIVPSPN-----FSVVLGINWLRLHAPEVDWARGRCTFHSPYCLK--------NCFRPP
PPCIALEKHSISLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-DV-FFECRSSAPWEPIAIRMQEEARQ-------------QADFWRLQ-
----SML--------SDTQDY---------------------------------------
---------------------------------VQIIPELFDQLHG-AAWFTKLEL-R--
---G--SVVEQSL--GIRGTE----E--------VWKAAFGLQPQDMKSYQPFRISPNPC
IPQSVIHFILQDMLGLCVLSYG-LEVLVYSMSQEEHLQHVRQVLVRFRYHNIYCSLNKSQ
FHRQTAEILGFTVCPKGVKLN------KTIMDLITEYPIPVSMGSLSLLMQHMYPYRHFV
EQFVITAEPLIRKLLS-------NAPFTWREEDQEAFEGL--------------------
-----KRAFRKAPRLYYPKPQNPFYLETG----VTRDALYASLIQVD-----EQTGKKIT
C-SF-------YSRNLS-------PLEVEYPPVEMKILPLRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFLFDVMEMPEEDG
SPS---LTPGRNRGWRALN---GRSMRP--------------------------------
-------LL----------------LLAMRGSL--------RN-----------------
-QS---------------------------------------------------------
-T------------DSES-DSDEDSE---EELLHQQTLIQELLSMIPIDQVLNSFL----
----AHFSMAQIR---------------------AVVLHFFRGLLYWKNLLALS------
----ALLVLLR----------------ARWQLSLPPAPTMEVARPQPR------HSLRLI
LDSTLLAGSGMASAIAQLLSQMPPLVGANTIPAQELAEL--FLGPGRW-QRNALHSQAPR
GLWFTPGFWLTLCEFFGVRVTPQEGNRPV-PYRNRYLELRVVGDEDVVLREALQ--DDLQ
SYRQCGLHDGLQDTSQDDQQASDGEDDDGGGGGGGG-----------GEGEGEAPPTPGA
AGTPPLRPHSLMDPEVLDFLNNRLLYIRGAQGQLSLLSREQV--TRALTRFLTMVYTQTL
PAPAPE-ARPREEARPADED-----DD--GLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------MRYYNRQTW---------------
------A---------------SVKPTPVT--------------------VI----DINK
KLLKTKR-RK------------GGRGGQEPGLHPHRSEA---------------------
---TPGRSPPTP-SLTLGPDCPP-----------------------PPPPPPPNDPSSS-
N---------SSSPCGGQRG--QYNPNLAERRRDDLSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTSLRE------------------------QVEPAP
E---EEE---------------------------DDIE-LCGAA------AAAAPATP--
-IE-EEC--------SEDLPEKFDGNPDALVPFMAQCQLFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMTEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQAELS-RLEVAKSLSALIGQCIHIER
RLARAA----AARKPRSPPRALVMPHVSN--HHQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKA--SPAGNSP
APL---------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MYTLI--------------------FI----YRNK
RVLKTKR-RR------------GARGGQDPGLHPPRSEA---------------------
---TPGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNN--NN-
---NN--------KPSGHKS--PCVPNMTERRRDELSEEINNLREKVIR-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
VP-EDDE---------------------------DDIE-LQGAA------AAAAPPAP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMEKS-TRDFSIDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEAPKSLSALIGQCIHIER
RLARAA----AARKPRSPPRALVMPHVSSH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKS--SP-----
----GPSATGPELIRSPPDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPIRVK-------DWPILVE----AIDGRPIASGPVVHETHNLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YTPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPHPSLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPNIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNHF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEYIPQVPGYQSYPT------------------
----------------YTTYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTM---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------FDGAREKLPTFLAQVDLYFLQISDLSFPTDTNKVAFIL
SLLTGPAGRWAVNVIRGNSPIKNNLVDFKAALTETFGDPLQKEN--AGWALYRLKQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLAFTAGLNDGLQDELS-RVEPAQNWDELVTKVCRIEA
RLEFRKKTHRTPVVEYH-----------ASAPVNS------------VQRKLSQ-----E
E---K----------------D-RRRRLRLCLYCGNEGHFAHNCSLKP------------
---------------------------------------------SQ-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LGPDCP-----------------------PPPPPPPPNGPSSS
SSSCSSSSSSSSSSRSAPRG--QYIPNLAERRRDDLSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTSLRE------------------------QVE---
PAPQDEE---------------------------DDLE-LRGAA------AAAAPPTP--
-LE-EEC--------PDDLPEKFDGNPDMLVPFMAQCQLFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMTEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQAELS-RLEVAKSLSALIGQCIHIER
RLARAA----AARKPRSPPRALVLPHITSH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKA--SPGKLPG
PAVEGPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRVK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------PP-----------------------AQPSFYYPVD-GYRV---YQPVRYY
YVQNVYTPVDENV-YPDHRLVDPTIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNSF--TIQNQ
YPRLSIPNLDDQ-----AHLATY----TEYVPQIPGYQTYPTY-----------------
----------------A-TYPTYPVGFAWYPVGRDGHGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTM---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QVE---
PTPEEEE---------------------------DDIE-LCGAA------AAAAPASP--
-IE-EEC--------PEDLPEKFDGNPDMLVPFMSQCQLFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMTEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VVDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQAELA-RLEVAKSLSALIGQCIHIER
RLARAA----ATRKPRSPPRALVAPHVNNHHNHQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKA--SPGKLPG
PAVEGPSATGPELIRSPQDDAASSPHLQVMLQIHLPGRHSLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPIVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPPLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------PP-----------------------AQPAFYYPVE-GYRV---YQPVRYY
YVQNVYTPVDENV-YPDHRLVDPNIEMIPGAHSIPSGHVYSLSESEMAALRDFVA-----
------RHVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRGPNGV--TIQNQ
YPRLTIPNLDDQ-----AHLATY----TEYVPQIPGYPTYPAY-----------------
----------------A--YPTYPVGFAWYPVGRDGHGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPPPPPPPSYSAL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-ILKPA----------------RTLIGEEPGLWLPKS-----------------------
----------------------------------------------VTYPFPQQVHNLW-
---KI--------CHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PERFDGSRNKLPTFLAQIELYFSQISAQAFPTDTSKVAFIL
SLLIGPVGQWATNLILGNDPVKDNLNDFKKLLSDTFGDPLRKEN--ASWALYRLKQGKGS
VLDYLNKFNSYSHQLDWGENAFMLLFIAGLNDYLQDELA-RLETAENWDALVAKVLRLDA
QFESRKQSRAMYAPAVS-------A---PRAPVAKGE-EP---MELGVFRKLST-----A
E---K----------------D-RRRQLGLCLYCGNAGHFARNCNVKP------------
---------------------------------------------SQLSGKERKKASR--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------FDGSRNKLPTFLAQTELYFSQISAQAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNDFKKLLSDTFGYPLRMEN--ASWALYRLKQGKGS
VLDYLNKFNSYRHQLDWGENAFMLLFIAGLNDYLQDELA-RLEPAENWDALVAKVLRLDA
RFESRKQSRAMYAPTVS-------A---PRAPVAKGE-EP---MELGVFRKLST-----A
E---K----------------D-RRRQLGLCLYCGNAGHFARNCNVKP------------
---------------------------------------------SQLSGKVRKACD---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------

---------------------MMEPSEDSFETMMELKNPSSKQMESSEGSSNTVEKTPGS
SGAQAQAEAGSDIQEGEEPS-------------------------------SGPFQEGEE
PSGPVQEGEEPSGPVQEGEEIPSGPVQEGEEGEEPSSGPVQE------------------
-----GEEPPSGPIQEGDEP-----SGPVQEGEEPPSGPVQEGE-EPSGPVKEGEEPPSD
PVQEGEEPPSGPVQEGEE-PSSGP--EGEEPSGPVKEGEEPPSDPVQEGEEQSSGLVQE-
------VEEPPSGPVQEGEEPS-SGPGEEPPSGPVQE---GEE----PPSDPVQEGEEG-
EE-PSSGSDQEMQ-------EL--------PTDEELSSDSYEESEDSYSDEDL-------
--DRTYYSSDPLS---EATDGID-SM------YGSQANDETDLEDR----S-GELEG-EG
QPRSSPEEVMATMGTI-----------ISMFLRMQDVRQQHIVT----------------
----EEILTQAMEDGQLPTIRRFSGDRRDYHEFLVLCQMTMQSH-ASMFYNDQLRVRFVM
RHLSGLALEWANALVEENSPLINDYEGFLQAMSDMFEYRQTLRV--AEDAMFKLRQGNRS
VADYINEFQSLVPTLGWPDEVLQAHLCHGLNEDIRHYLF-RIPQPNSLKNLMVVVLQIED
KLAERRAVLRLPPESRPRN--MTWMDSPAP-------------EKWRVSSWLSH-----T
YHPDI----------------D-RAHLFLLLMVRVSPYQ---SVAVQA------------
---------------------------------------------LVDSGAEGNYMDEKF
AQEHYVELYEK-------PYPQAIK----TVDGSLIGNEPIWLYTEPLMCIQQNHYEYIE
FDIVPSPH-----YSVVLGIKWLRTHAPDVDWTRGRCTFHSPYCLK--------NCFHPP
PPCIALEKYSVSLLPGLPH---------------------------SY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDRN-DV-FYESPSKVPWESVAARMQQKA-------------RQQEEYWILY-
----DML--------TDRQDY---------------------------------------
---------------------------------VQMMPELFDQLHG-AAWFTKLEL-R--
---R--DIKGTNETYSVSHTE----D--------TWKATFGLTDHQMRCYRPFTLCSFAD
KSDNEIHSILKDILGFYVICRG-QEVLIYSMTQEEHYEHVRQVLLRFRHNNVYCSLDRSQ
FHCQTAEIMGFALFPKGVKLN------KTLMNLITGCPAPGNRRCLQAIIELMYPYRHFV
EHFAIIAEPLVRQLLS-------SAPFYWGEEEQEALECL--------------------
-----KRAFRKSPILYHPKPQNPFYLETG----ITGSSLYASLIQTD-----EETGKKAT
C-AF-------YSRKLS-------PMEVDYPQVELRILPIRASFMVWSRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFHFDVMELPDQDD
TRAL---SYRRSQNQRGFRGR---FLRPLLLLALRGGQRDLSSESQ--------------
------------------------------------------------------------
------------------------------------------------------------
------------------SEDSEDESYQESAELNRQSLVQELLSTIPIEQIFNSFL----
----AQINMAQVR---------------------AFVYNFFYCLLRWKSVVSVA------
----ALLVIMRV---------------KRQQVSPLPGPSLEVDYPPPR------HTLRLI
LDSSLIAGSGMVTALIQLFSQMPPLLGANTIPARQLAEM--FIRPRCW-QRNALHSQPPR
GLRFTPGFWFTLCHFFGIRANPEEDVFPG-PHERRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQDNDVQEA----------------------------LLGDQE
--AVTFRPQDLLDPEVLAFLNNRLLYILGADGRLTLISRDEV--AQALTRFLIMASRIRP
PPP------PSNTL------SSSDDEL--D--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------INK
RVLKTKR-RR------------GGRGRHDPGRQPQRSGA---------------------
-TPTPGRSPPTP-AVLMGPADCP-----------------------PPPPPPPPNNNNNN
NNSNS--------RPSGHKS--PCVPNMTERRRDELSEEISNLREKVIR-----------
---QSE-NSNLQNQV---QKLTEENGTLCE------------------------QV--EP
TS-QDNQ---------------------------DDIE-LQGAA------AAAVPSTP--
-TE-EEC--------PEDFPEKFDGNPDTLSPFMSQCQIFMEKG-TRDFSVDRIRVCFVT
SMLTGRAARWASAKLERSNYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDRIQEELS-HLEVAKSLSALIGQCIHIER
RLARAA----AARKPRSPPRALVLPH---H--HQVDPTEPIGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKS--SP-----
----GPSATGPEILRSQDD--SLSPHLQVMLQIHLPGRHTLFVRAMVDSGASGNFIDHEY
VAQNRIPLRVK-------DWPILVE----AIDGRPIASGPIVHETHNLIVDLGDHREVLS
FDVTQSPF-----FPIVLGVRWLSTHDPNITWSTGSILFDSEYCRYHCRM------FSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPHPSLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPRIEMIPGAHSIPSGHVYSLSEPEMAALRNFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRSPNNF--TIQHQ
YPCLTIPNLDDQ-----AHLATY----TEYIPEIPGYQSYPA------------------
----------------YANYPTYPVGFAWYPVGRDNQGRA-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MVNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEV---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIANH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSESDMAALRDFVA-----
------RNVKDGLITPTVAPNGAQILQ----VKRGWKLQVS--YD-CRAPNNI--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MENK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIK-----------
---QSEENSNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDDD---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHVASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAQQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MVNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHVASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAQQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------M----NRNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIR-----------
---QSEENSNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDDD---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHVASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAQQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------M----YKNK
RVLKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQSQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREV--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------RNK
KLLKIKR-RK------------SGRGGQDSGLHPHGSEA---------------------
---TPGRSPPTP-TLTLGPDCPP-----------------------PPPPPPPNAPSSA-
S---------SSSSRRGQRG--QYIPNLADRRRDDLSEEINSLREKVMK-----------
---QSEENNNLHNQV---QKLTEENTSLRE------------------------QVEPAP
Q---DEE---------------------------DDIE-LRGAA------AAAAPPTP--
-IE-EEC--------PDDLPEKFDGNPDALVPFMAQCQLFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMTEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQAELS-RLEVAKSLSALIGQCIHIER
RLARAA----AARKPRSPPRALVLSHITH--HHQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKAAKA--SPAGNSP
APL---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PERFDGAREKLPTFLAQVDLHFLQISDLSFPTDTNKVAFIL
SLLTGPAGRWAVNVIRGNSPIKNNLVDFKAALTETFGDPLQKEN--AGWALYRLKQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLAFTAGLNDGLQDELS-RVEPAQNWDELVTKVYRIEA
RLEFRKKTHRTPVVEYH-----------ASAPVNSGE-EP---MQLGVQRKLSQ-----E
E---K----------------D-RRRRLRLCLYCGNEGHFAHNCSLKP------------
---------------------------------------------SQLPGKGCMRSRY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------FPTDTNKVAFIL
SLLTGPARRWAVNVIRGNSPIKNNLVDFKAALTETFGDPLQKEN--AGWALYRLKQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLAFTAGLNDGLQDELS-RVEPAQNWDELVTKVCRIEA
RLEFRKKTHRTPVVEYH-----------VSAPVNSGE-EP---MQLGVQRKLSQ-----E
E---K----------------D-RRRRLRLCLYCGNEGHFAHNCSLKP------------
---------------------------------------------SQLPGKGCMRSRY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MAAAGGSDCP-----------------------PPPPPPPPNDNNNN
NR---------------PSS--PVSILGRRRRRRAQHNGDNGNGEDQWE-----DRRR--
-Y-HVYWLPSANNRL---RY----------------------LPQEEEEPEPEPEQVQIQ
VPGEGEE---------------------------EEEE-LQGAT------AAPSPALL--
-FG-DDC--------LDDLPFKFDGNAEMLNQFLSQCRAFLEKG-TRALADDRSRVCFVT
SMLIGRAARWATAKLDRYTYLMHNYEAFMLELKLVFEDPERREA--AKRRIRRLRQGPDS
VADYGNEFHMLALELDWTEPALIDQFLEGLSDAMHEELA-HEEIPDTLTELINLCIYIER
RMARDAAAAAAA-------AAAVAAA-----ASQTDPTEPVGGAR----MRLSQ-----E
E--------------------KERRRKLNLCLYCGSGGHYADNCPAKASK----------
---NGPSATGPQRTRSPPPEA-VTTHFQVMLQIHIPGRHTLFVRAMIDSGASGNFIDQDY
VIQHGIPLRIK-------EWPIMVE----AIDGHPIASGPIVLETHHLIVDLGDHREILS
FDVTQSPF-----FPIVLGVRWLSTHDPHITWSTRSIVFNSDYCRFRCRM------YSQI
PPAVLLPVIYP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------PHPPFFYHTD-GYRVFHVLYPVRYY
YVHNVYTPVDEHV-YPGHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALREFVD-----
------RNVKNGLMTPTVAPNGAQVLQ----VKRGWKLQVT--YSNCRAQHQSCAAQHNS
YHRMTLPNLGDH-----AHLASY----GEFVPHIPGYH----------------------
---PIP---------AYATLAGHHVTFAWYPVGRDIHGRM-----ILVPVVITWCPHWHH
HH--------IHPVPQYPPPQPPPPPPP----PPPPPPSYSSL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------NLLQRLREQEAQQDQIIQWLQRLSERLDALQQQ--PASPTPASLPG
GGSSHTASAMYVFEPKVPFPEKFSGERSKFFAFQEACKLYLSYL-PRSFPTEELKVNFVM
TLLLGDPQLWGFSLP-PSDPARTSLDSFFKAMAIIYDDPDRSAS--ADSAIRNLRQGKRR
VEDYCTEFRRWAVETGWNDIALRSQFRIGLS DAVKDSLI-NFPASSSLDSLMYLPIQIDR
RHRERRQEKVSAASPQPSH--TEFIPRPEVAFSKPSE-EP---MQLGST-RLSS-----E
E---K----------------D-RRQAN GLCLYCGDKGHFRSTCPKRP------------
---------------------------------------------GNYTPMGNRLSDL--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MYVLI--------------------FI----YSNK
RVLKTKR-RR------------GARGGQDPGLHPPRIEE---------------------
---APGRTPPTPPV-AMGPADCP-----------------------PPPPPPPPNNNNNN
NSK--------------PKG--PCVPNMTERRRDELSEEINNLREKVIR-----------
---QSEENSDLQNQV---QKLTEENSTLRE------------------------QVEPPE
PEEEDDE---------------------------DDIE-LQGAA------AAATPATP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMSQCQVFMEKS-TRDFSLDRVRVCFVT
SMMTGRAARWASAKLERSNYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGQGS
VVDYANAFQMIAQDLDWNEPALIDQFHEGLSEQIQEELS-RGEAPKTLSQMINQCIHIER
RLARAA----AARKPRSPPRAMVAPQMSGH--QQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKAS-----------
KSSPGPSATGPELTRSPQEEASSTPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VVQNAIPVRVK-------DWPILVE----AIDGRPIASGPVVHETHELIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYRCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------PP---------------------APQQPSLYYPVD-GYRI---YQPLRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIRNQ
YPRLSIPNLDDQ-----AHLATY----TEFVPQVPGYQSYPTY-----------------
----------------T-TYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTM---------------------
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--------------------------------------

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----------------------FDGTREKLPTFLAQVDLYFLQISDLSFPTDTNKVAFIL
SLLTGPAGRWAVNVIRGNSPIKNNLVDFKAALNETFGDPLRKEN--AGWALYRLKQGKGS
LIDYLNKFNLLKHQLDWGEHAFMLVFTAGLNECLQDELS-RVEPAQNWDELVTKVCRIEA
RMEFRKKTRGPPVVEYH-----------ASASVNSGE-EP---MQLGVQCKLSQ-----E
E---K----------------D-RRRRLRLCLYCGNVGHFAHGCTLKP------------
---------------------------------------------SQLPGKGGNVPAMQ-
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
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---------------------------------------------------------INK
RVFKTKR-RR------------GGREGPDPGLQPQRSEA---------------------
-TPSPGRVPPTP-AVTMGLGDCP-----------------------PPPPPPPPNNNNN-
---NS--------KPSGHKS--PCVPNLTERRRDELSEEINNLREKVIR-----------
---QSEENSNLQNQV---QKLTEENSTLRE------------------------QVEP--
TPENDVE---------------------------DDLE-LQGAA------AAVVPSTS--
-TV-EDC--------PEDLPERFDGNPDMLAPFMSQCQIFMERS-TRDFSLDRVRVCFVT
SMMTGRAARWASAKLERSNYLMHNYPAFMMELKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVPKSLSALIGQCIHIER
RLARAAA-----AAPRSPPRALVLAH--HH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKS--SP-----
----GPSATGPEIIGSQDD---LASHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VLQNRIPLRIK-------DWPILVE----AIDGRPIASGPIVHETHELIVDLGDHREVLS
FDVTQSPF-----FPIVLGVRWLSTHDPNITWSTRSIFFDSDYCRFHCRM------YSPV
PPALA-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------PVPHPSLYYAVD-GYRV---YQPVRYY
YVQNVYTPVDHHV-YPDHRLADPQIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTVAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNE
YPRLSIPNLDDQ-----AHLATY----AEFVPEVPGYPSYPA------------------
----------------YATYPTYPVGFAWYPVGRDAQGRA-----LFVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPSSFSAM---------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
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--------------------------------------------------------MRNR
KLLKTRR-RK------------GGRGGQDTGLHSHRSEA---------------------
-T-TPGRSPPTP-TITLGPDCPP-----------------------PPPPPPPNDPSSP-
----------SHSPCSSQRG--QYNPNLGERRREDLSEEINNLRERVMK-----------
---QSEENNNLHNQV---QKLTEENTTLRE------------------------QVEPAA
E---EEE---------------------------DDIE-LCGAA------AAAAPATP--
-IE-EEC--------PEDLPEKFDGNPDMLVPFMSQCQLFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMTEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VVDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQAELA-HLEVAKTLSALISQCIHIER
RLARAA----AARKPRSPPRALVASQVNNHHHHQADPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKASKA--SPAGNSP
APL---------------------------------------------------------
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------------MATAAGGAGCP-----------------------PPPP---PNNNNNN
NK---------------SKS--PRNGGRRRRNRRQS------------------------
------------------------------------------------------------
---RNSD---------------------------SDPE-LQGA--------TADPSFF--
-LD-EDC--------LEYLPEKFDGNPDALTPFIAQCQVFMEKS-SRDFSVDRTRVCFVT
SMLHGRAARWATAKLERCNYLMNNYRAFMLELKHVFEDPQRREA--AKRKIRRLRQGAGT
VSEYAGIFQSVAQDLDWDESSLVDQFLEGLNQQIHQELSRRSEVPTNLNDLIRLCIHIER
RLVRLAAEAASRPRDPPRGLGLPLPQ-----SSQSDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGNGGHYADNCPAKGNNNRNSPSGNS-
---PAPL-----------------------------------------------------
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--------------------------------------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVQGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLEEMEELTTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAQEEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPIWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----DQTGKRAY
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFEVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDESNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSVLPAPTMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGRW-QRNALHSQTHR
GLQFTPGFWMTLCEFFGVRVTPWEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTGA
SPPPRPR--HLMDPQVLEFLSSRLLHIRGADGQLHLLSREQA--VGALSQFLTLIYRQAL
PVPAWE-SQPREEARLEELPDED-EDA--DLD------

---------------------MIEPSEDSFETMMERKNPSSKQMESSEGSSNTTVETPGS
GARQA---------------------------------------------------AAAA
AGPA-------GGLAREAGALPIDLLQAME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHREIKDPPNDLLQDL-----------
------------------EGSLKGA-RPDAG-----------------------------
------------------------------------------------------------
---------GPLGAA---PGKTEG-ASDHPRGGQDEQAGATDQAGSDEQK--SPEE----
QAGSEMAEIMAQVRSL-----------ISLYLRMQDLIEQQRVA----------------
----EAVLAKGLHEGRMPIPATFSGDRREYHEFIVLCQLILQSY-PGMYYSDRLRVGYVM
CHLSGMALEWAKDLMEKNSPLVSDFPAFLEAMSDMFE YRQTLRV--AEEAMFNLRQGDRA
AIEYINEFQGLVPTLGWPDEVLQAHLCQGLKEEIRHYLF-RIPQPESLDSLIVLVLQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPQ-----E
GHPSL----------------D-RDHLFLLLLVRVNPYH---SV AVRA------------
---------------------------------------------LVDSGASANFMDERF
AQEHYVQLFEK-------PYPQQVQ----TVDGSLIGNEPVWLYTEALVCIHQNHQETIE
FDIVPSPN-----FSVILGINWLRVHAPEVDWVKGRCTFHSPYCLK--------NCFRPP
PPCIALERHAISLLPGLPP---------------------------LY------------
------------------------------------------------------------
----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDQS-EG-FYGYGYYAPWEPMGARMQDRARL------------LRDEFWDPR-
----NML--------TNRQDY---------------------------------------
---------------------------------VQMIPELFDQLHG-ATWFTKLEL-R--
---G--TIVEEGV--DIHHTE----D--------VWRAAFGLDLQEMTSYQPFLICADPI
IPQSVIHFILKDVLGFFVLSYG-QDVLIYSMSQEEHRQHVRHVLVRFRYHNVYCSLDRSQ
FHRHTVEFLGFVLTPKGVKMN------KSIVRTITGYPVPGSKKSLRHLMEFAFPYRHFV
ERFAVITEPLVRQLLT-------HRPFYWGDEEQEAFECL--------------------
-----KRAFRKAPLLYHLKPQNPFYVETG----VTRTSLHASLIQVD-----EHTGKRVP
C-AF-------YSRNIS-------PIEVGSSLLEMKILPIRAAFMVWCRYLEN-------
------TEEPVIILLSPEDLA-----SLNNDRLTVLLPGHWVFFFSHFKFDVMELPDPDG
GRP---PPFRRNLGR-RAF-RYNAATRP--------------------------------
-------TT----------------LFATRGSP--------RD-----------------
-QA---------------------------------------------------------
-P------------DSEE-EEEENEDAPFQDEPSGQSLQQEFLALIPVDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLFWKNIVAVA------
----ALLVLLR----------------FRRRLALLPAPSQDVARPQPR------RPLRLI
LDSSLITGSSIATAIAQLLTQMPPLLGANAIPAEELAEL--FLGPGRRRQRHTLVPQSRQ
GPQFTPRFWLTLGEFFGVRVAPREATQPG-PRQNLCLELHVVDDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDEQENDVQEN---------------------------EALSSDA
SGAPAPRQHLPTRTAVLAVLSHRRLYIRGAQGQSLLIHRELA--ARAPTSLLTTFHARAP
PMGVWG-SPPPAGTTLEEQPSDG-EDA--ELD------

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------MDELRAKVDQLQTA-------------
---FTVSQTAFAVKGHVLTPERFDGTRCKLPTFLAQVELYFSQLSAHAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNNFKKLLTDTFGDPLRTEN--AGWALYRLKQGKGT
VLDYLNKFNLYRHQLDWGENAFMLLFTAGLSDMLQDELA-RLEPAESWDALVAKVLRLDA
RFEARKHSKAMCAPPMH-------V---TRAPVVMGE-EP---MELGVFKKLST-----E
E---K----------------S-RRRQLGLCLYCGNAGHFAKNCNVKP------------
---------------------------------------------SQLSGKGQP------
------------------------------------------------------------
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--------------------------------------

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--------------NLLQRLREQEAQQDQIIQWLQRLSERLDALQKQ--PAAPTPASLPG
GGSSHTASAMYVFEPKVPFPEKFSGERSKFFAFQEACKLYLSFL-PRSFPTEELKVNFVM
TLLLGDPQLWAFSLP-PSDPARTSLDSFFKAMTIIYDDPDRSAS--ADSAIRSLRQGKRR
VEDYCTEFRRWAVETGWNDIALRSQFRIGLS DAVKDSLI-NFPASSSLDSLMYLAIQIDR
RHRERRQEKVSAASPQPSH--TEFIHRPEVAFSKPSE-EP---MQLGST-RLSS-----E
E---K----------------D-RRRAN GLCLYCGDKGHFRSTCPKRP------------
---------------------------------------------GKRQSLSRSDCPH--
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MRNK
RVLKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVMK-----------
---QSEENNNLQSQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREV--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHIASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKS--SPGKLPG
PAVEGPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAPQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLTEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------

---------------------MIEPSEDSFETMMELKNPSSKQMESSEGSSNTVEETPGS
SGAQAGAQAEAQAETQVEAQVEAQVEAQAEAQVEAQVEAQVEAQVEAQVEAQVETQAGSD
SGPAQEEKEPPSGPLKEMQELPTNLLQEVE---EPSSGPQEEM-QEIPTDLLLEVEEPSS
GPHQEMQELPTDLFLEVEEPS----SGPHQEIQELPTDLLL-------------------
-------------EEMQELPTDLLWEVEEPSSGPHQEMQELPTDLLQEVEEPSSDPCEA-
------SSNDLP---QDMEESSDDGSNQESSDGSNHELSNGSNHESSFGSNPESSDVSN-
LE-SSGGSNQESSDGSQKESSYDSNPELSDNSNQELSDNSNQESSDSSN---------QS
SDISNQEGSDPLSEA---SDYSM-DETINSSNTQSDQDD-TDLGDDEEEEEEEDGEE-EG
QPKNSPEEVVATMGNV-----------ISLFLRMQDLKEQQRVA----------------
----ERLMMQAINEGRLPSLRPFSGDRRDYHEFVVLCQMTMQNY-PSMLYNDELRVKFVI
CHLTDLALEWANDLVEQNSPVINNFSAFLEAMSEKFEYRQTLRV--AEDAMFNIRQGNRC
AADYINEFRGLIPTLGWPDEVLQAHLCQGLNEEIRHYLF-RIPQPNSLDNLIVLILQLEE
KLAERRALLRLPPESRPRS--VAWMDAPAP-------------EKWRVSSWLPN-----E
FHPDI----------------D-RDHLFLLLLVRVDPYH---SVAVRA------------
---------------------------------------------LVDSGAEGNYMDERF
AQEHYVELYEK-------PYPQIIQ----GVDGIPIGNEPVWLCTEPLVCVHQKHYEYIE
FDILPSPN-----FSIVLGMKWLRTHAPEVDWVRGRCTFHSPYCLR--------NCFTPP
PPCIALEKYSISLLPGLPH---------------------------TY------------
------------------------------------------------------------
----SDLADVFNPREADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDQR-GV-FYESGGRETLEPVSARMQEKARQQEKA-------REQEEYWILY-
----DML--------TDRQDY---------------------------------------
---------------------------------TQMVPELFDQLHG-AAWFTKLEL-L--
---G---IKEGEMRHTVTHTE----D--------TWRASFGFGIHQMRCYRPFTMSSFSD
EGNSIVHFILKDILGLFVICHG-REVLVYSMSQEEHSQHVRQVLVRFRYHNIYCSLDKTQ
FHRQTAEILGFNISPKGVKLN------KNLMNLIVGCPVPGSRRCLQSVIDLVYPYRHFV
ENFAVIAAPLVRQLLS-------SEPYYWGEEEQEALESL--------------------
-----KRAFRKSPILYHPKPQNPFYLETG----ITGSFLSASLVQTD-----DVTGKKST
C-AF-------YSRPLS-------TMEVEYPRVEMRILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFGVMEMPAEGD
TQAL---F-RRCWNQRGFRAR---FLRPLLLMSIRANLNYLDRSSEIEDKEDNE--EEEE
EEDGEE-EEGEEEED---GE-EEEGEEEEEGEEEEDGEEEEDG----EEEEDGEEEEDGE
EEEEDGEEEEDGEEE-GEE-EEDEEEEGEEEGEEEGEEEEEEEEGEEEEEEGEEEEEEGE
EEEEEEEEEEEDEFEEEFEEEEEFEEEEEEEDEEEPSMVRELLAAIPMDHILNGFL----
----AHFSVAQIR---------------------AIVLNFFRGLLYWKSVLGVA------
----AVLVMLRA---------------R-QPLSPVPAPNLEVARPQHR------HTLRLI
LDSTLIASSGMATAIAQLLSQMPPLVGANTLPARELAEL--FLGPRCW-HRNALHSQPPR
GMRFTPGFWLTLCEFFGVRVNPEDDVFPD-PYQHRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQDNDVQED----------------------------LFGDQE
--AVTFRPRNLLDPEVLDFLNNRLLYTLGTDGRLTLLSRDQV--AQALTRFLAMASRMAL
PSP------AREQARLEELSDSD-DEL--D--------

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------KLPTFLAQVELYFSQLSAHAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNNFKKLLTDTFGDPLRTEN--AGWALYRLKQGKGT
VLDYLNKFNLYRHQLDWGENAFMLLFTAGLSDMLQDELA-RLEPAESWDALVAKVLRLDA
RFEARKHSKAMCAPPMH-------V---TRAPVVMGE-EP---MELGVFKKLST-----E
E---K----------------S-RRRQLGLCLYCGNAGHFAKNCNVKP------------
---------------------------------------------SQLSGKVKKQTKR--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------FDGSRNKLPTFLAQIELYFSQISAQAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNDFKKLLSDTFGDPLRTEN--ASWALYRLKQGKGS
VLDYLNKFNSFRHQLDWGENAFMLLFIAGLNDYLQDELA-RLEPAEDWDALVAKVLRLDA
RFESRKQSRAMYAPSVS-------A---PRTPVAKVE-EP---MELGVFRKLST-----A
E---K----------------D-RRRQLGLCLYCGTAGHFARNCNIKP------------
---------------------------------------------SQLSGKGNFKMCF--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------FDGTRCKLPTFLA-------QLSAHAFPTDTSKVAFIL
SLLTGPAGQWATNLILGNDPVKDNLNNFKKLLTDTFGDPLRTEN--AGWALYRLKQGKGT
VLDYLNKFNLYRHQLDWGENAFMLLFTAGLSDMLQDELA-RLEPAESWDALVAKVLRLDA
RFEARKHSKAMCAPPMH-------V---TRAPVVMGE-EP---MELGVFKKLST-----E
E---K----------------S-RRRQLGLCLYCGNAGHFAKNCNVKP------------
---------------------------------------------SQ-------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMERKNPSSKQMESSEGSSNTTVGTPGS
GAQEA---------------------------------------------------AGAA
S-----------GPAQERKELPIDLRQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPHREIKDPPNDLLQDL-----------
------------------EESRNAA-RQEVG-----------------------------
------------------------------------------------------------
---------DPTGEA---PGGMEE-ASVNPWGAQDQEVNDTDLANVEE-E--ESPEE---
--DSETSEIMATVRSI-----------ISLYLRMQDLREQQRVA----------------
----EEILMEGISAGRLPVPSKFSGDRREYHEFIVLCQLILQSY-PRMFYNDRLRVGYVM
CHLSGMALEWAKALVEEDSPLIDDFPAFLEAMSGMFEYRQALRV--AEDAMFNIRQGSRP
AIEYINEFRGLVPTLGWSDEVLQAHLCQGLN EEIRHYLF-RVPQPDSLDSLIVLVLQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSNWMPC-----Q
ARPTV----------------N-RDHLFLLLLVRVNP YH---SVAVQA------------
---------------------------------------------LVDSGAGGSFMDEKF
AQEHYVELYEK-------PHPKMVQ----GVDGSLIGDEPVWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVILGIDWLRLHTPEVDWIQGRCTFHSPYCLQ--------KCFRPP
PPCIALERHAISLLPGLPP---------------------------LY------------
------------------------------------------------------------
----SDLADVFNPKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSIAPWEPVGAGMQNSARP-------------RDESWNPD-
----SML--------TNRQDY---------------------------------------
---------------------------------VQVIPELFDQLHG-ATWFTKLEL-R--
---G--TVVEEGM--NINQAE----D--------VWKAAFGFEPQEMKSYRPFPLSSDPT
IPQNVLHFILKDMLGYFVLSYG-RDVLVYSMSQEEHFQHVRQVLVRFRHHHVYCSLDRSQ
FHRHTVEFLGFVITPKGVRLN------KSIVNTVTGYPTPGSKKSLRHLIEFILPYQHFV
ERFHIIIEPLARLLLT-------EDAFSWGDDEQGAFNCL--------------------
-----KRAVRRAPLLHHPKPQNPFYLETG----VTKTALHASLSQRD-----DQTGRRVS
C-AF-------YSRSIS-------PIETDYSQLEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFDVMERPAQDG
GRR---LPPPRNLGRG---------ART--------------------------------
-------RS----------------PFSPGGSP--------GA-----------------
-RS---------------------------------------------------------
-L------------DSTE--DEEAEDTPAQGPPSRRNLQQEFLARIPIDQILHSV-L---
----AHVSVAQIR---------------------AVVLHFFRGLLFWKDTLAVA------
----ALLVLLK----------------LKRRXXXXXXXXXXXXXXXXX------XXX---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
-----------------------------MLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRVK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------PP-----------------------AQPSFYYPVD-GYRV---YQPVRYY
YVQNVYTPVDENV-YPDHRLVDPTIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNSF--TIQNQ
YPRLSIPNLDDQ-----AHLATY----TEYVPQLPGYQTYPTY-----------------
----------------T-TYPTYPVGFAWYPVGRDGHGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTM---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MVNK
RILKTKK-RR------------SGRGGQDPGLHPHRSEA---------------------
---TAGRSPPTP-TVTLGPDCPP-----------------------PPPPPPPNNNNNN-
---NS--------KHTGHKS--ACVPNMTERRRDELSEEINNLREKVIK-----------
---QSEENNNLQNQV---QKLTEENTTLRE------------------------QV--EP
TP-EDED---------------------------DDIE-LRGAA------AAAAPPPP--
-IE-EEC--------PEDLPEKFDGNPDMLAPFMAQCQIFMEKS-TRDFSVDRVRVCFVT
SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREA--AKRKIRRLRQGMGS
VIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELS-HLEVAKSLSALIGQCIHIER
RLARAAA---ARK-PRSPPRALVLPHVASH--HQVDPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGTGGHYADNCPAKASKA--SP-----
----GPSATGPEIIRSPQDDA-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEY
VAQNGIPLRIK-------DWPILVE----AIDGRPIASGPVVHETHDLIVDLGDHREVLS
FDVTQSPF-----FPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRM------YSPI
PPSLP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---------------------PAQQPPLYYPVD-GYRV---YQPVRYY
YVQNVYTPVDEHV-YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVA-----
------RNVKDGLITPTIAPNGAQVLQ----VKRGWKLQVS--YD-CRAPNNF--TIQNQ
YPRLSIPNLEDQ-----AHLATY----TEFVPQIPGYQTYPT------------------
----------------YAAYPTYPVGFAWYPVGRDGQGRS-----LYVPVMITWNPHWYR
----------QPPVPQYPPPQPPPPPPPP-PPPPSYSTL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVQGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLEEMEELTTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLSGA---SDRMKE-ASVNPSGAQEEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPIWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHNVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----DQTGKRAY
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFEVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDESNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSVLPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGRW-QRNALHSQTHR
GLQFTPGFWMTLCEFFGVRVTPWEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTGA
SPQPRPR--HLMDPQVLEFLSSRLLHIRGADGQLHLLSREQA--VGALSQFLTLIYRQAL
PVPAWE-SQPREEARLEELPDED-EDA--DLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---RRRDKLVDTIPNLLQRLREQEAQQDQIIQWLQRLSERLDALQQQ--PAAPTPASLPG
GGSPHTASATYVFEPKVPFPEKFSGERSKFFAFQEACKLYLSFL-PRSFPTEELKVNFVM
TLLLGDPQLWAFSLP-PSDPARTSLDSFFKAMAIIYDDPDRSAS--ADSAIRNLRQGKRR
VEDYCTEFRRWAVETGWNDIALRSQFRIGLS DAVKDSLI-NFPASSSLDSLMYLAIQIDR
RHRERRQEKVSVASPQPSH--TEFIPRPEVAFSKPSE-EP---MQLGST-RLSS-----E
E---K----------------D-RRRAN GLCLYCGDKGHFRSTCPKRP------------
---------------------------------------------GNYTPMGNRLSDL--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMEHKNPSSKQMESSEGSSNTTEATSGS
GVQGE---------------------------------------------------AGPA
SGPAQEKKEPPSGPLEEMEELTTDLLQDME------------------------------
------------------------------------------------------------
----------------------------EPSSGPRKEIEDPPNDLLQDM-----------
------------------EESCNGS-HQARG-----------------------------
------------------------------------------------------------
---------DPLNGA---SDRMKE-ASVNPSGAQEEQEAHTDLKESGREE--TPQEE-QN
QTEHSTAELMAMVRSI-----------ISLYFRMQDLKEQQRVA----------------
----EEILIKGINAGQLPAPKHFSGDRREFHEFIVLCQLTLQSY-PRMFCNDRLRVGYVI
NHLSGLALEWAKALLQENSPLMGDFPAFLEAMSEVFEYRQTLRV--AEEAMFTIRQGSRS
ATEYIDEFQSLVPILGWPDEVLQAHLCQGLNEEIRHYLF-RVPQPDSLDSLIVLILQIEE
KLAERRAMLRLPPEARPRN--LTWIDSPAP-------------ERWMVSSWLPS-----E
VHPGI----------------N-RAHLFLLLMVRVNPYH---SVAVQA------------
---------------------------------------------LVDSGADGNFMDEKF
AQEHYVELYEK-------PYPQPVQ----SVDGSLIGNEPIWLYTEPLVCIHQNHQESIE
FDIVPSPN-----FSVVLGIRWLRVHAPEVDWIKGRCTFHSPYCLK--------NCFRPP
PPCIALERHGMSLLPGLPH---------------------------PY------------
------------------------------------------------------------
----SDLADVFNPKEADEETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHS-ET-FYECPSTAPWEPVGARMQERARL-------------QEEYWDLQ-
----DML--------TDRQDY---------------------------------------
---------------------------------IQMIPELFDQLHG-AAWFTKLEL-R--
---G--TIVEESV--NVHRTE----D--------VWKAAFGLELQEMKSYQPFALSPDPI
IPQNVIHFILKDMLGFLVLSYG-QEVLIYSMSQEEHLHHVRQVLVRFRHHSVYCSLDKSQ
FHRQTVEFLGFVVTPKGVKLN------KNVMTIITGYPTPGSRLSLRNFIEFVFPYRHFV
ERFSIIAEPLVRQLLS-------SDQFYWGVEEQEAFECL--------------------
-----KRAFRKAPLLHHPKPQNPFYLETG----VTSTALHASLIQID-----DQTGKRAY
C-AF-------YSRNIS-------PIEVEYSQVEMKILPIRAAFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWVFFFSHFNFEVMELPEQDG
GRA---LPPVRNLRWRRAF-QRNTAARQ--------------------------------
-------TL----------------LLASRGFP--------RD-----------------
-PA---------------------------------------------------------
-T------------ESG---EEENED---QDESNEQTLQQELLATIPIDQILNSFL----
----AHFSMAQIR---------------------AVILHFFRGLLYWKNTLALA------
----AILVLLR----------------VRQCLSVLPAPAMQVARPQPQ------RSLRLI
LDSSLIAGSSITTAITQLLTQMPALAGANTIPARELAEL--FLGPGRW-QRNALHSQTHR
GLQFTPGFWMTLCEFFGVRVTPWEGRLPA-LRENRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDKQDNDVQEA---------------------------SPSHTGA
SPPPRPR--HLMDPQVLEFLSSRLLHIRGADGQLHLLSREQA--VRALSQFLTLIYRQAL
PVPAWE-SQPREEARLEELPDED-EDA--DLD------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------SCP-----------------------PPPPPPPPNNNNNN
NK---------------PPG--RQSRQARRSNRR-----------LRYR-----------
---PDVGIDSE--------------------------------P----------EE-PQT
QASGSSE---------------------------SESE-LQGAA------AAADPLFY--
-VD-EES--------LQYLPEKFDGNPDAVTPFIAQCQIFMEKS-TRDFSVDRNRVCFVT
SMLLGRAARWATAKLERCGYLMNNYRAFMMELKHVFEDPQRREA--AKRKIRRLRQGMGT
VGEYAGAFESIAQDLDWNESSLVDQFLEGLNTDIHSELTRRTEVPTNLNDLIRLCLHIER
RLARAAAEAANKPRADPP-RALVAPQ-----SHQADPTEPVGGAR----MRLTQ-----E
E--------------------KERRRKLNLCLYCGSGGHYADNCPAK-------------
---EGPSATGPERTRSPPPEA-PTAHLQVMLQVHIPGRHTLFVRAMIDSGASGNFIDQDY
VIQNGIPLRIK-------EWPIMVE----AIDGHPIASGPIVLETHHLIVDLGDHREVLS
FDVTQSPF-----FPIVLGVRWLSTHDPHITWSTRSIVFNSDYCRFRCRM------YSQV
PPALLFPVPHP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------PHPPFFYHTD-GYRVYH---PVRYY
YVQNVYTPVDEHA-YPGQRLVDPHIEMDPGAHSVPGGHVYSLSETEMAALREFVD-----
------RNVKNGLMTPTVAPNGAQVLQ----VKRGWKLQVT--YN-CRAPHNC--TVQNQ
YLRMSLPNAGDQ-----AHLANY----SEFAPHVHGYHHHH--HH-------------YH
HHHHLP---------AYATYAGHHMMFAWYPVGRDIHGRM-----ILTPVVITWCPHGYH
HH--------PHPVPQYPPPQPPPPPPPPPPPPPPPPPSYSTL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------------------MIEPSEDSFETMMELNNPSSKQMESSEGSSNTVEEAPGS
SGAQAQAEAGSDSGP---------------------------------------AQEG--
-------KEPPSGSTQEMQELPIDLYQNLE---EPFSGLYEE------------------
-----REKLPTDLLQDMEET-----SGPREERDELPTDLLQELEESSSGPFEEREELPTD
TLEDVEEPSSGPREEREELPTDTL--ENEPSSGPREEREELPTDTLENVEEPFSDPCEE-
------QEDPPNM-----EESC-DSSHEE-------------------------------
------------------------------------------------------------
-------EEDPLSEIAISSDGID-SVFVNSSETQTEQGDETDLEDE----DELNLGE-EA
QPGGSPEEVMATMESI-----------ISVFLRVHDIEHQQRVA----------------
----ERILMQAIEEGRLPKLRHFSGDRREYHEFIVLCQMTLQNY-PSMFHNDQLRVKFVM
CHLSDLALEWANGLVEQDSPLLNNYSGFIEAMSEMFE YRQTLRV--AEDAMFNIRQGNRG
VAEYINEFQSLVHTLGWPDEVLQAHLCQGLNEDIRHYLF-RIPQPASLENLMVLVLQIED
KLAERRALLRLPPEARPRS--LIWMDTPAP-------------EKWHVSTWLPN-----A
FHPNI----------------N-RAHLFLLLMVRVN PYH---SVAVQA------------
---------------------------------------------LVDSGAEGNYMDEKF
AQEHYVELYER-------PYPQAVQ----TVDGSLIGNEPISLCTEPLLCIQQNHCEYIE
FDIVPSQH-----FSVVLGIKWLRTHAPEVDWFKGRCTFHSPYCLK--------NCFHPP
PPCIALEKVSMTILPGLPQ---------------------------MY------------
------------------------------------------------------------
----SDLADVFIVKEADDETSDQPSSDG----------------------SDDLSESEPS
ELQQAGDSDHN-DV-FYESSSKRPYQSVSARMQEKA-------------RQQEQYWILY-
----DML--------NDRQDY---------------------------------------
---------------------------------IQMMPELFDHLHG-ATWFTKLEL-R--
---D--IAKEPRVDYSLTHTE----D--------TWRATFGMSPYQMRCYRPFTIDSYAD
DCDNEIHFILKDILGFYVIAHG-RELLIYSMSQEEHSDHVRQVLLRLRGHNIHCSLDKTL
FHRHSAEFMGFALSRKGVKLN------KTIRNIMMGCPVPSNRKSLQSVIELFYPYRHFV
EHFAIIAEPLVKLLLS-------SEPFCWGEEHQEALDCL--------------------
-----KRAFQKAPFLYHPKPQNPFYLETG----VTGSFLYASLLQTD-----EETGKKAT
C-SF-------YSRHLS-------PIEVEYPQVEMRILPVRASFMVWCRYLEN-------
------TEEPIMILLNTEDLA-----SLNNDRLTVLLPGHWLYFFAHFHYEVMELPDDDD
PRAL---SR-RNPNQRALRAR---YMRPLLLLALRASQREAFSDFGSEPE----------
----------------------------------------------------------AE
T-----------------------------------------------------------
-----------------ESEDSDDESDPEWAELNR----QEALSNIPIEQILNTLL----
----THFSRVQIR---------------------SVVLHFFRGLLYWKSVLGVA------
----SLLVMMRV---------------R-QPLSPLPAPSLEVARPEPR------HTLRLI
LDSSLIAGSGMATAITQLLSQMPRVARANTLPARELAEL--YLSPRCW-HRNALHSQPPR
GLRFTPGFWLTLCEFFGVRVNPEEDIFPD-PHQQRYLELHVVGDEDVVLREALQ--DDLQ
RYRQCGLHDGLQDTSQDAQDNDVQEALLEDEEALLGNQEDLLGDQEALLGDQEALLGNQE
--AVTFRPRNLMDPEVLDFLNNRLLYILGADGRLTLLSRDEV--ARALTRFLTMASRMAL
LSP------AREQARLEALSDSSDDEL--D--------

Query Results

"ENSGT00880000138027_0"

ENSGT00880000138027_0