Query Results 

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--VLVFC-------------------LSC-
-LLLLSLW--SQSS-ARGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1203)

PSGPT---PLPIIGNI-------LQL-----DV-K-----
----------DIG--K-SL----TNF---SKVYGP-VFTVYFGL----K-PIVVLHGYEA
V---KEALIDHGEE-FSG--RGSFP---V-AEKV-NKG-----------LG----ILFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSIV
FHKRFDYKDQ-RF-LNLMEKFNENLRLLSS-----------PWI-----QV----C----
-NNFPA-LI----DYLP-GS--HNKVLK-NFAYVKNYVLE---RIKEHQ----ESLDVNN
-PQDFID-----------CFLIKME-Q--------EKHNQQ-SEFTIENLI-ATVTDVFG
AGT-ETTS-TTLRFGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSHMPYTDAVMHEIQRYIDLVPTS-VP
HAVT-TD--IKFRNYLI--PK---------------------------------------
-----------------------GT-A-IMT--SLTSV-LHSD-KEFPNPKTFD-----P
GHFLDKNGNFK--KSDHFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MEIFLFLTTILQ-NFNLKS
VGDI---KNLNTTX-XXXXX-X-------XXXX----X---------XXXXXXXXXXXXX
XXXXXXXX-----------------------------X----------XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXQMTSAEFQT-----L-------------------NQGFI
YFDAGILFLLILVI-FFHCAKMYFLMMSSNLDRL-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAILGIT-----M--ALLVW-------------------VVT-
-LLLISIW--KRIY-SSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNL-------LQL-----DI-K-----
----------DIP--K-SF----T---RLAKRYGP-VFTVYLGS----R-RTVVLHGYKA
V---KEVLLTHKNE-FSG--RGEIPVFHE----YKDKG-----------------IIFN-
-NG--P-TWKDVRRFSLSILRDY--GMGKQGNE--ARIQREAGFLVEE------LR-KTQ
----GQ-P----F------------------------D-PTFLLGCA----PCNVIADIL
FHRRFDYKDK-TC-LRLMRLFNEDFYLLST-----------PWL-----QL----Y----
-NNFSD-YL----YYMP-GS--HRKVMK-NVSEIKAYALE---RAKENL----QSLDPSC
-PRDVTD-----------CLLAEMEK---------EKQSGKLSMYTMENIS-VTLADLFF
AGT-ETTS-TTLRYGLLILMKYPEIE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPT-RIPAVKDRLEMLYMDAVVHETQRFINLVPSN-LP
HEAT-RD--TVFQGYLI--PK---------------------------------------
-----------------------GT-I-VIP--TLDSL-LYDD-QEFPEPEQFK-----P
EHFLNENGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLLLTAILQ-HFNLKS
LVEP---KDIDLKP-IAIGF-G-------TIPP----H---------YKLCLIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFI--ILAIC-------------------LSC-
-LILLFLW--NGSN-TKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIVGNI-------LQL-----NS-K-----
----------NIS--K-SI----S--ML-AKDYGP-VFTVYFGM----K-PTVVLHGYEA
I---KEALIDHGEE-FSG--RGSFP---V-IDRI-TQGL-----------G----VIFS-
-NG--E-RWKQTRRFSIMVLRNM--GMGKKTIE--DQIQEEALCLVAA------LQ-KTN
----AS-P----C------------------------D-PTFLLGCV----PCNVISAVI
FQNRFDYSDK-KF-QTLIKYFNENFENVST-----------PWI-----QL----Y----
-NAFPF--L----RVLP-GS--HNVIFK-NYALQINFILE---KVKEHQ----ESLDISN
-PRDFID-----------YFLIQME-K--------EKHNKQ-SEFTMDNLV-ATIWDMFS
AGT-ETTS-TTLRYGLLLLLKHPEIS----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---QVVGKN-RRPCMQDRSRMPYTDAVVHEIQRYINLVPTN-LP
HAVT-QD--TRFREYFI--PK---------------------------------------
-----------------------GT-T-ILT--HLSSV-LYDD-KEFPNPEKFD-----P
GHFLDESGNFK--KSDYFMAFS-AGK----------------------------------
--------------------------RA-CA--GEGLAR--MELFLILTTILQ-NFTLKP
LVDP---KDIDITP-VHRGL-G-------SVPP----F---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLLV--FLVLC-------------------ISC-
-CLLLSFW--KQSS-QKRRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------NIS--K-SL----S--NL-SKIYGP-VFTVYLGM----K-PTVVLHGYET
V---KEALIDFGEE-FSA--RGSFP---L-ADRA-TNG-----------NG----IINS-
-NG--K-KWKDIRRFSLMTLRNF--GMGKRSIE--NRVQEEAHCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FQHRFDYRDP-DF-LSLMEKFNENFRILNS-----------LWL-----QI----C----
-NALPI-LM----DYFP-GS--HNKVFK-NINFFKNYVLE---KTKEHQ----ASLDTNN
-PRDFID-----------CFLIKMQ-E--------EKHDKD-LEFTLENLT-ITASDLFA
AGT-ETTS-TTLRYALLLLLKHPEVM----------------------------------
------------------------------------------------------------
-------AK-AQ----E---E---------------------------------------
--------------IE---RVIGRH-RSPCMQDRSNMPYMDALVHEVQRFIDLLPLN-LP
HAVT-RD--IKFRNYII--PK---------------------------------------
-----------------------GT-T-IIT--SLTSV-LHDE-REFPNAKMFD-----P
GHFLDESGKFK--KSDYFMAFSA-GK----------------------------------
--------------------------RS-CV--GESLAR--MELFLFLTTILQ-KFNLKS
VVDP---KDLDTTP-VASGF-T-------SVPP----S---------YKLCFVPL-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LV--
LMVFMSVW--WQR-ELWGKLPPGPT---PLPFIRNY-------LQL-----DTEQ-----
-----------IY--D-S-------LMKISKRYGP-VCMVHLGP----R-RVVVLRGYEA
V---KEALLDQAEE-FSG--RGELAVADR----I-FKG--------------YEFMPLCF
SLP--V-SAPSLCSFSLDV-SSF--SVTVRLISALEPLSSVTVCLLSFS----------S
----SQ-L----L------------------------C-FLVFLSP-----SPTLSPSLI
LESHIISASN-AF-LALRQVPLPSI-LPFP-----------SSV--

PF00067 // ENSGT00880000137861_0_Domain_2 (587, 1107)

PHPQL----Y----
-EMFYS-VM----KHLP-GP--QQQAFK-ELQGLEDFITK---KVEQNQ----RTLDPNS
-PRNFID-----------SFLIRMQQ---------EQKNPN-TEFCLKNLV-LTTLNLFI
GGT-ETVS-I-TRYGFLLLMKHPDIE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFADVAPMS-LA
RRVI-KD--TKFRGFLI--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPHDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-GKR---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEWSG-A---VTA--LLVVY-------------------VSC-
-LLLISAK--RKLS-QKGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPLIGNF-------LQI-----KS-T-----
----------KTL--Q-SL----LK---LRDEYGS-VFTVYFGT----R-PILVLCGHQA
V---KEALIDKAEE-FSG--RSTLP---T-LERN-FQGHG---------------VVFA-
-NG--E-RWKQMRRFSLTVLRNF--GMGKKSIE--ERIKEEAQFLLEE------FQ-KMK
----EK-P----F------------------------E-PTYFLSRA----VSNIICSIV
FGDRFDYEDK-EF-QALMEMMNNSFREMST-----------GWA-----QF----Y----
-DIYVD-FL----KYFP-GP--HTKIYN-ILEDMRVFIAK---RVKKNQ----ETFDPNF
-PRDFID-----------CFLIQMEK---------EKGNPT-TEFNVKNLE-LNTLNLFF
AGT-ETVS-STLRYGFLLLMKYPEVQ----------------------------------
------------------------------------------------------------
-------AK-MH----E---E---------------------------------------
--------------ID---RVIGHN-RVPNIEDRSQMPYTDAVIHEVQRFSDLLPMD-LA
HRVI-RD--TEFRGYLL--PK---------------------------------------
-----------------------GM-E-VYP--LLTTV-LHDP-TMFKSPNTFN-----P
ENFLDEDGRFK--KNDAFVPFSS-GK----------------------------------
--------------------------RM-CL--GEALAR--MELFLFFTTTLQ-SFQLKS
LVLP---EDIDLTP-QESGF-A-------NIPP----F---------YQLSIIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------KGPFSVL------L--FLALL--------------------AGF
LLLLV--R--GHPK-ARGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 465)

PPGPR---PLPFLGNL-------LQM-----DR-K-----
----------GLL--N-SF----M--K-IQEKYGD-VFTVYLGP----R-PVVMLWGTEA
I---REALVDQAEA-FSG--RGTIA---V-VKPV-FQDY----------G-----VVFA-
-NG--E-RWKALRRFSLATMRDL--GMGKRSIE--ERIQEEAQCLPVS------QN-KP-
----------------------------------------LFPT-----------SCSS-
LGD--------------------FYDLLGP-----------SFL-----QV----Y----
-ELFSE-FL----KYFP-GT--HRQIAK-NLQEVISFIGQ---NVETHR----ATLDPSA
-PRDFID-----------AYLLRMEK---------EKSNQH-TEFHQQNLI-ISLLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVHEEIE---QVIGSH-RVPALDDRTKMPYTEAVIHEIQRFSDLIPIG-VP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILTSA-LHDP-RYFEKPDTFN-----P
DHFLDSSGGLK--KNDAFIPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-RECGVG--------KVPP----T---------YQIRFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVLGV--FLGLV-------------------LSC-
-LLLLSLW--RQSS-QRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQV-----DL-K-----
----------NIS--K-SL----R--DL-SKVYGP-VFTLYLGS----K-PAVVLHGYEV
V---KEALIDHGEE-FSG--RGSLP---A-VDKI-KKGL-----------G----IIFS-
-NG--K-NWKETRRFSLMTLRNF--GMGKRSIE--ERVQEEARCLVEE------LR-KTN
----GA-P----C------------------------D-PTFILGCA----PCNVICSII
FQNRFNYKDQ-DF-LNLINILNENANILSS-----------PWM-----QV----C----
-NNFPV-IT----DYLP-GS--HAKLLK-NFTFLKHYCLE---KVKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKHNSN-VECTYDNFA-VTTSDLFA
AGT-ETTS-TTLRYSLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRN-RSPCMQDRTHMPYTDAVLHEIQRYIDLVPTS-LP
HATT-SE--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIT--SLTSV-LNDD-KEFPNPERFD-----P
GHFLDENGKFK--KSDYFFPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFHLES
PVDP---KDLDTTP-VVSGL-I-------AVPP----K---------FQICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--TLLAC-------------------LM--
VMVLMSVW--RQR-KIWGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISERYGS-VFTIHLGP----R-RVVVLCGYDA
V---KEALVDQAEE-FGG--RGEQATFNW----L-FKG--------------YGV-AFS-
-NG--D-RAKQLRRFSITTLRYF--GVGKRGIE--ERIQEEAGFLIEAFRG-------TR
----GA-I----I------------------------D-PTFFLSRT----VSNVISSLV
FGDRFDYENK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFYS-VM----KHMP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIHMQE---------EQKNPN-TEFSMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYMEAVIHEIQRFGNMIPMG-LA
RRVT-KD--TKFRGFLL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSKPQDFN-----P
QHFLDEKGQFK--KSDGFVPFSV-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTIMQ-NFCFKS
PQSP---QDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDSMST----AVL--LLLLA-------------------LVCL
FLT-Q------S-SRGKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPR---PLPLLGNL-------LQL-----RS-Q-----
----------DLL--T-SL----T---KLSKKYGS-VYTVYLGP----R-RVVVLSGYEA
V---KEALVDQGEE-FSG--RGEYP---V-FFNF-TKGN----------G-----IAFS-
-NG--E-RWKVLRRFSVQILRNF--GMGKRSIE--ERILEEGGFLLEE------LR-KTE
----GE-P----F------------------------N-PLFMLSRS----VSNIICSVI
FGKRFDYDDE-RL-LTIIHVINDNFQIMSS-----------PWG-----EM----Y----
-NLFPS-LL----DWVP-GP--HQRIFQ-NFGNLRDLISG---SVREHQ----ATLDPNS
-PRDFID-----------CFLTKIA-Q--------EKENPL-SHFHMDTLL-MTTQNLIF
GGT-ETVG-TTLRHAFLALMKYPKIQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---RVVGRS-RLPTLEDRAAMPYTDAVIHEVQRFADVIPMN-LP
HRVI-RD--TAFRGFLI--PE---------------------------------------
-----------------------GT-D-IIT--LLNTV-HYDP-SQFLKPQEFN-----P
EHFLDANQSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GESLAR--MELFLYLTAILQ-SFSLQP
LGKP---EDIDLTP-LGSGL-G-------NLPR----P---------FQLRLLER-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFI--VLVIC-------------------LSC-
-LISFFLW--NQNR-AKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----NT-K-----
----------NVS--K-SL----S--KL-AENYGP-VFTVYFGM----K-PTVVLYGYEA
V---KEALIDRSEE-FSG--RGHFP---L-LDWT-IQGL----------VG----IVFS-
-NG--E-KWKQTRRFSLTVLRNM--GMGKKTVE--DRIQEEALYLVEA------LK-KTN
----AS-P----C------------------------D-PTFLLGCA----PCNVICSII
FQNRFEYDDK-DF-LTLLEYFHENLLISST-----------SWI-----QL----Y----
-NAFPL-LI----HYLP-GS--HHVLFK-NIANQFKFISE---KIKEHE----ESLNFSN
-PRDFID-----------YFLIKIE-K--------EKHNKQ-SEFTMDNLI-ITIWDVFS
AGT-ETTS-TTLRYGLLVLLKHPDVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IH---RVVGRH-RSPCMQDRSCMPYTDAVVHEIQRYIDLVPNN-LP
HSVT-QD--IKFREYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDE-KGFPNPDQFD-----P
GHFLDENGSFK--KSDYFMAFS-AGK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLLLTNILQ-HFTLKP
LVDP---KDIDTTP-IANGL-G-------ATPP----S---------YKLCFVPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MSALGVS-----V--ALLVW-------------------VAV-
-LLLVSIW--RQVH-SSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNL-------FQL-----EL-K-----
----------NIP--K-SF----T---RLAQRFGP-VFTLYVGS----R-RVVVVHGYKA
V---REVLLDHKDE-FSG--RGDIPAFHA----HRDRE-----------------VYCN-
-NG--PKPWKDIRRFSLTTLRNY--GMGKQGNE--SRIQREAHFLLEA------LR-KTQ
----GQ-P----F------------------------D-PTFLIGCA----PCNVIADIL
FRKRFDYNDE-KF-LRLMYLFNENFQLLST-----------PWL-----QL----Y----
-NNFPS-LL----HYLP-GS--HRKVMK-NVAEIKEYVSE---RVKEHL----QSLDPNC
-PRDLTD-----------CLLVEMEK---------EKHSAE-RLYTMDGIT-VTVADLFF
AGT-ETTS-TTLRYGLLILMKYPEIG----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RIPAIKDRQEMPYMDAVVHEIQRFITLVPSN-LP
HEAT-RD--TIFRGYII--PK---------------------------------------
-----------------------GT-V-IVP--TLDSV-LYDN-QEFPDPEKFK-----P
EHFLDESGKFK--YSDYFKPFS--------------------------------------
-----------------------AGKRV-CA--GEGLAR--MELFLLLSAILQ-HFNLKP
LVDP---KDIDISP-VNIGF-G-------CIPP----R---------FKLCVIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------VCVTKPT-S---AL-----LTY-------------------GIF-
-LVLISAW--KWRH-KEGRF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPM---PLPFFGNL-------LQL-----NP-K-----
----------DLP--K-SF----LA---LSHKYGT-VYTLYLGP----R-RVVVLCGHEA
L---KEALVDHAEQ-FCG--RGEMP---Y-VEQT-FKGSG---------------IVLA-
-NG--E-RWKKLRHFTLITLKNF--GMGKCSIE--ERIQKEAQYLLEK------FR-KLK
----GL-P----F------------------------D-PTFLLSCT----TANIICSIV
FGKRFEYEDK-IF-LSMLDLTNKIFFELST-----------PWA-----KL----Y----
-DMYFG-IM----QYLP-GG--DSHIYN-LLQELKALIGE---RIKLNQ----ETLDPKN
-PRDFID-----------CFLIEMNK---------EKRNPS-TEFTVTNLV-LTVLNLFT
AGT-ETVS-STLKYALLLLMKYPKVE----------------------------------
------------------------------------------------------------
-------EK-VH----Q---E---------------------------------------
--------------ID---SVVGRN-RTPAVKDRMNMPYTNAVIHEIQRLVDILPAG-LP
HKVM-ED--TEFRGYLL--PK---------------------------------------
-----------------------DT-N-IIT--LLGSA-LHDP-KYFCDPETFN-----P
EHFLDQEGGFK--KNDAFVPFSS-GK----------------------------------
--------------------------RA-CV--GESMAR--MELFLYFTNILQ-SFSLKS
SLAP---TDIDISP-QLNGF-L-------NIPP----V---------YQLCLIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----GQ

PF00067 // ENSGT00880000137861_0_Domain_2 (487, 1252)

-P----F------------------------D-PTICLTHT----VSNVICSIV
FGDRFDYEDQ-KF-LTLINLLEENNDLFRS-----------VLV-----QV----Y----
-NFFPT-FM----SYLP-GP--HKKILK-NSQELISFVRE---IIKMHK----ESLDPSC
-PRDFID-----------AFLIKME-E--------ERQNGQ-SVFNTDNLV-RSTIDLFL
AGT-GTTS-TTLRHGLLLLLKYPDVE----------------------------------
------------------------------------------------------------
-------EK-VH----E---E---------------------------------------
--------------ID---RVIGRN-RSPCMVDRSQMPYTDAVIHEIQRFVNLVPFS-LP
HAVT-KD--VRFREYVI--PK---------------------------------------
-----------------------GT-T-VFP--SLESV-LRDS-KEFPNPEQFN-----P
GHFLDENGAFK--KSDFFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLVLTVILQ-NFTLKP
LIDP---KDIDVTS-IPSPV-I-------FAPK----P---------YRLCVLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-KSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISERYGP-VFTIHLGS----R-RVVVLCGYDA
V---KEALLDQAEE-FSG--RGKQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLTEVLRG-------TR
----GA-N----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------SMG--Q---L----Y----
-EMFPS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPSS
-PRDFID-----------SFLIRMRE---------EEKNPN-TEFYLKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEMQRFGDMIPLG-VA
RRVT-KD--TKFRDFIL--PKGT-------------------------------------
--------------------------E-VFP--LLGSV-LRDS-RFFSNPRDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTIMQ-NFRFKS
PQSP---KDINVSP-KHVGFA--------TIPP----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------N-ASMDPVV--VLVLC-------------------LSC-
-WLLLSLW--KQSS-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPFIGNI-------LQL-----DV-K-----
----------DIS--K-SL----S--NL-SKAYGP-VFTLYFGM----K-PTVVLHGYEA
V---KEALVDLGED-FSA--RGNFP---I-GEKA-NRG-----------HG----IIFT-
-SG--S-TWKKMRRFSLMTLRNL--GMGKTDLE--SRVQEEASHLVEE------LR-KTN
----GL-P----C------------------------D-PTFVLGCA----SCNVICSII
FQTHFDYTDQ-AL-IGILERLNENLRILSS-----------PWI-----QV----Y----
-NSFPA-LI----EYLP-GG--HHTILQ-NSDFIKNYILE---KIKEHQ----ESLDFNN
-PRDFID-----------YFLMKMG-Q--------EKYNKQ-FEFTFENLM-NTAVDLFG
AGT-ETTS-TTLRYGLLLLLKHPDVE----------------------------------
------------------------------------------------------------
-------AK-VQ----D---E---------------------------------------
--------------IE---RVIGRH-QSPCMQDRSRMPYTNAVLHEIQRYIDLVPNN-LP
HAVT-RD--IKFRNYVI--PK---------------------------------------
-----------------------GT-T-VLT--SLTSV-LHDS-QEFPNPEIFD-----P
AHFLDDGGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFMTNILQ-KFSLKS
LVDL---KDIDTTP-IASGF-G-------HVPP----P---------YQLCFIPM-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELGG-A---FTI--FLALY-------------------LSC-
-LLILIAW--KRTN-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PIPFLGNL-------LQV-----RT-E-----
----------GTF--Q-SL----MK---LHEKYGS-VFTVYMGP----R-PVVVLCGHEA
V---KEALVDQADD-FSG--RGEIA---S-IERN-FQGYG---------------VALA-
-NG--E-RWRILRRFSLSILRDF--GMGKRSIE--ERIQEEASYLMKE------FW-KTK
----GA-P----I------------------------E-PTFFLSRT----VSNVISSVV
FGSRFDYEDK-QF-LNLLQLINESFIEMSI-----------PWA-----Q-L---Y----
-DMYSG-IM----QYFP-GR--HNRIYY-LIEKLKDFIAS---RVKINE----ESLDPQN
-PRDFID-----------CFLIKMHQ---------EKNNPH-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGXXXXXXXXXXX----------------------------------
------------------------------------------------------------
-------AK-IY----E---E---------------------------------------
--------------IN---QVIGPH-RIPSVDDRSKMPYTDAVIHEIQRLTDIVPMG-VP
HIVI-RD--TQFRGYFL--PK---------------------------------------
-----------------------GT-D-VYP--LLGSV-LRDP-KYFCYPDAFY-----P
QHFLDEQGCFK--KNEAFVPFSS-GK----------------------------------
--------------------------RV-CL--GESMAR--MELFLYFTSILQ-NFSLHS
LVPP---ADIDITP-RISGF-G-------NIPP----I---------YKLCLKAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLALL--------------------LGF
LVLLV--R--GHPK-SHGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPH---PLPFLGNL-------LQM-----DR-G-----
----------GFL--S-SF----M--Q-FREKYGD-VFTVHMGP----R-PVIMLYGTEA
I---REALVDQAEA-FSG--RTTHA---V-AKPI-FKDY----------G-----VIFA-
-NG--E-RWKVLRRFSAVTMRDF--GMGKWSVE--KRIQEEAQCMLDE------LR-NSQ
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFDYNNR-QF-LHLLNLFYQTFSLSSS-----------LSG-----QL----Y----
-ELFSV-FL----KYFP-GV--HVQVCK-NMQEILDFIEQ---SVEKHK----VSLDPNN
-PRDFID-----------AYLLRMEK---------EKSNPD-TEFHHQNLM-ITVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLIM
LKYPHVA-EKVQKEID---QVIGSH-RLPTLEDRPKMPYTEAVIHEIQRFSDIIPIG-VP
RKVT-KD--TWFRGYLL--PK---------------------------------------
-----------------------NI-E-VYP--ILSSA-LHDP-QYFEQPDTFN-----P
DHFLDANGALK--KNEAFMPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PVDP---KDIDLSP-KESGFG--------RLPP----E---------YKICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--ALVLG-------------------VSC-
-LLLLSVW--RHRS-GRGEL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------DIS--K-SL----R--HL-SKVYGP-VFTLYLGM----K-PIVVLHGYEA
V---KEALVDHGEE-FAG--RDSIP---I-LKRR-KKNI-----------G----IVFS-
-NG--K-TWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FKNRFDYQDP-DF-LTLMNKINENVRILSS-----------AWA-----QV----Y----
-NNFPA-LI----DYLP-GR--HHILFK-NIDYIINYILE---KVKEHE----ESLDVND
-PRDFID-----------CFLIKMA-QE---K-----DNQG-LEYTYENLV-YAASDLFN
AGT-ESTS-TTLRHALLLLLKHPQVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IQ---CVIGRH-RSPCMQDRSRMPYTDAVLYEIQRYIDLLPVN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-A-IWT--SLTSV-LHDN-KEFPHPEIFD-----P
GHFLDEHGNLK--KSDYFMPFSS-GK----------------------------------
--------------------------RM-CV--GESLAR--MELFLFLTTILQ-HFHLKS
QVDP---KELNNTP-IANGL-T-------SLPP----L---------YKLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------SLGSGS----LAG--SLRAC-------------------VPGA
VFXLL--R--GH-RAGGGNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPLLGNL-------RQL-----WG-P-----
----------SLL--H-SL----L---ALRDQYGP-VFTIYMGP----H-RAVVLWGYEA
V---KEALVDHAEE-FSG--REGLA---L-AERT-SKG----------NG-----LFFS-
-NG--E-TWRQLRRFALSTLRDF--GMGKRSIE--ERIREEAHYLLEE------LG-KTK
----AL-S----L------------------------G-PPHDSPPP----ILQVLLTGQ
XGALFDYADQ-EF-QTLLSLIQANFRRVDT-----------VWV-----QL----Y----
-EMFSG-LL----RFLP-GP--HNRILV-HVGVLHDFVTG---RMRRNQ----ETLDPSC
-PRDYID-----------AFLIKME-E--------EKQNPH-SEFHARNLT-LSTVHLFF
GGT-EMVS-ATLRYGFLLLAKHPEVQ----------------------------------
------------------------------------------------------------
-------EE-VE----S---V---------------------------------------
--------------XG---PAAAGA-RSPAAEDRSRMPYTQAVIHEVQRFCYVLPLG-IP
HAVS-RD--TQFRGYTL--PK---------------------------------------
-----------------------GT-D-VLC--ALGSA-LRDP-GHFRDPERFN-----P
GNFLGEDGRFQ--KNPAFMAFSA-GK----------------------------------
--------------------------RI-CL--GEGLAR--LELFLFLTTVLQ-RFALTW
PGDP---QEIDLTP-QGSGF-W-------NLPP----E---------YQICAVPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MEPTPLSVL------L--LFALL--------------------TGL
LILLI--R--GRPK-ARGHLPPGPR---PLPFLGNL-------LQM-----DR-K-----
----------GLL--K-SF----L--R----KYGD-VFTVYLGP----R-PVVIICGTEA
I---REALVDQAEV-FSG--RAKIA---V-VDPV-VQGH----------G-----VIFA-
-NG--E-RWKALRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LQ-KSQ
----GA-L----Q------------------------D-PVFYFHSI----TANIICSIV
FGKRFDYRDP-QF-LRLLELLFQSFVLISS-----------LPS-----QL----F----
-ELYSS-FL----KHFP-GS--HRQIYK-TCRKSTGE-------------------GQQA
-PPPLMG-----------APPTR-LQ--------

PF00067 // ENSGT00880000137861_0_Domain_2 (695, 1251)

-DKSDPR-SQFDHRNLI-MSALSLFF
AGT-ETTS-TTSG-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---PFFCAERVLKEID---RVIGSD-RPPALDDRAKCIH-----RRNSKIWTLLPIG-VP
HMVT-KD--THFRGYIL--PRYST------------------------------------
-----------------------SL-E-VYP--ILSSA-LHDS-RYFEKPDDFN-----P
AHFLDANGAVK--KNDRI------------------------------------------
-----------------------------CL--GEGIAR--TELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-QESGVG--------NVPP----K---------YQIRFLPRQRG--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVL--VLVLT-------------------LSC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------DIS--K-SF----T--NF-SKIYGP-VFTLYFGP----K-PTVVVHGYEA
V---KEALDDLGEE-FSG--RGSFP---I-VERM-NNGL----------G-----VIFS-
-NG--T-KWKELRHFSLMTLRNF--GMGKRSIE--DRIQEEASCLVEE------LR-KTN
----GS-L----C------------------------D-PTFILSCA----PSNVICSVV
FHNRFDYKDE-NF-LNLMEKLNENFKILNS-----------PWM-----QV----C----
-NALPA-FI----DYLP-GS--HNRVIK-NFAEIKSYILR---RVKEHQ----ETLDMDN
-PRDFID-----------CFLIKME-Q--------EKHNPR-TEFTIESLM-ATVSDVFV
AGS-ETTS-TTLRYGLLLLLKHTEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RRPCMQDRTRMPYTDAMVHEIQRYINLIPNN-VP
HAAT-CN--VRFRNYVI--PK---------------------------------------
-----------------------GT-D-LVT--SLTSV-LHDD-KEFPNPEVFD-----P
GHFLDENGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RM-CV--GEALAR--MELFLLLTTIVQ-NFNLKS
FVDT---KDIDTTP-MANTF-G-------RVPP----S---------YQLCFIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFV--VLVIC-------------------VSI-
-LIFLFLW--NQRH-AKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1220)

PPGPT---PLPVIGNI-------LQI-----NI-K-----
----------NIS--K-SI----S--KL-AEDYGP-VFTLYFGM----K-PTVVLHGYEA
V---KQVLIDQSEE-FSG--RGSLP---V-ADNI-NQGL-----------G----IIFS-
-NG--E-QWKQTRRFSLMVLRNM--GMGKRTIE--HRIQEEALCLVEA------LK-KTN
----GS-P----C------------------------D-PTFLLTYA----PCNVICSII
FRNRFEYSDE-NF-LTLAKYIHENATIFST-----------PWI-----EL----Y----
-NAFPS-LL----HYLP-GS--HNTLFK-NMTEQRKFILE---KIKEHQ----ASLDLNN
-PQDFID-----------YFLIKME-K--------EKHNKQ-SEFTMDNLI-TTVWDVFT
AGI-ETTS-ITLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------DD-GQDEILE---E---------------------------------------
--------------IN---RVVGRN-RSPCMQDRSRMPYTDAVIHEIQRYIDLVPNN-LP
HAAA-QD--IEFREYLI--PK---------------------------------------
-----------------------GT-T-ILP--SLTSV-LHSD-KEFPNPEQFD-----P
GHFLDKSGNFK--KSDYFMAFS-AGK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLLLVSILQ-QFTLKP
LVDP---KNIDTTP-LLKGS-G-------SIPH----F---------YEVCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLALL--------------------VGF
VLLLV--R--GHPK-ARGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--N-SF----M--K-LREKYGD-VFTVHLGP----R-PVVMLYGTEA
I---REALVDQAEA-FSG--RGTIA---V-VRPV-FKDY----------G-----VIFA-
-NG--E-RWKTLRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFLFQGI----TANIICSIV
FGERFDYKDR-QF-LRLLDLFYRSFSLFSS-----------FSS-----QV----F----
-ELFSG-FL----KYFP-GA--HRQISR-NLREILDFIGQ---SVEKHR----ATLDPSN
-PRDFID-----------TYLLRMEK---------EKSNKD-TEFHHENLI-VSVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHIT-EKVQKEID---QVIGSH-RLPTLEDRTKMPYTEAVIHEIQRFSDLIPIG-VP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDR-RYFEQPDTFN-----P
DHFLDANGALK--KNEAFMPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PMVP---KDIDLNP-KESGFG--------KVPP----T---------YQVCFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLP----LV--ALLVF-------------------LS--
IVILMSVW--QHR-RLHGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------IMKIKEQYGP-VFTIHLGP----R-RVVVLCGYDA
V---KEALIDQAEE-FSG--RGKQATFDW----I-FKG--------------YGV-AFS-
-SW--E-RARHLRRFSISTLRDF--GMGKRGIE--ERIQEEIGFLIESFRE-------TQ
----GA-F----I------------------------D-PTFYLSRA----VSNIISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFYS-VM----KYLP-GP--QQQAFK-ELQGLENFIVK---KVEQNQ----RTLDPSS
-PRNFID-----------SFLIRIQK---------N---SN-AEFHMKNLV-MTTLSLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---RVIGRN-RHPMFEDKAKMPYTDAVIHEIQRFGDMIPMN-LA
HSVT-KD--TKFRNFLL--PKGT-------------------------------------
--------------------------E-VFP--VLGSV-LRDP-KFFSNPQDFH-----P
QHFLDEKGQFK--KNDAFVPFSL-------------------------------------
------------------------GKRY-CL--GEGLAR--MELFLFLTSILQ-NFRFKS
PQAR---QDIDVSP-KLVGFA--------TIPQ----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDSFV--VLVLC-------------------LSC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNI-------LQI-----DI-K-----
----------DIS--K-SL----T--NL-SKVYGP-VFTLYFGL----K-PIVVLHGYEA
V---KEALIDLGEE-FSG--RGHFP---L-AERA-NRGF-----------G----IVFS-
-NG--K-KWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FRKRFDYKDQ-QF-LNLMEKLNENVKILSS-----------PWI-----QI----Y----
-NNFSP-II----DYFP-GT--HNKLLK-NVAFMKSYILE---KVKEHQ----ESMDMNN
-PQDFID-----------CFLMKME-K--------EKHNQP-SEFTIESLE-NTAADLFG
AGT-ETTS-TTLRYALLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRN-RSPCMQDRSHMPYTDAVVHEVQRYIDLLPTS-LP
HAVT-CD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-ILI--SLTSV-LHDN-KEFPNPEMFD-----P
HHFLDEGGNFK--KSNYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLFLTSILQ-NFNLKS
LVDP---KNLDTTP-VVNGF-A-------SVPP----F---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLGV--VLGLV-------------------LSC-
-LLLLSLW--RQSS-QRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQV-----DL-K-----
----------NIS--K-SL----K--NF-SKVYGP-VFTLYLGR----R-PAVVLYGYEA
V---KEALIDRGEE-FSG--RGSFP---V-SEKF-KKGL-----------G----IVFS-
-NG--N-NWKEMRRFSLKTLRNF--GMGKRSIE--DRVQEEARCLLEE------LR-KTN
----GL-P----C------------------------D-PTFILGCA----PCNVICSII
FQNRFDYKDQ-EF-LNLMENLNENGKIMSS-----------PWM-----QV----C----
-NNFPA-II----DYLP-GS--HNKLLK-NFTFLKHYCLS---KVKKHE----ESLDINN
-PRDFID-----------CFLIEME-Q--------EKHNPK-KEFTYENFV-FTASDLFA
AGT-ETTS-TTLRYSLLLLLKHPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSSMPYTDAVLHEIQRYIDLLPTN-LP
HSVT-CD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIT--SLTSV-LHDN-KEFPNPEIFD-----P
GHFLDKSGNFK--KSDYFIPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
PVDP---KDLDTTP-VANGF-V-------SVPP----T---------YQICFIPF-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (329, 1252)

LREKYGD-VFTIFLGS----R-PVVVLCGPDT
V---KEALVEKAEE-FSG--RGPIA---M-VDSV-FQGL----------G-----VIFS-
-NG--H-TWKTLRRFSLATLRDF--GMGKRSIE--ERIQDEAQCLVEE------LR-KSK
----GE-E----I------------------------I-QHHLLH-------------CI
WVKRFSYHDD-MF-QELLNKFNETFVLTSS-----------AWG-----QL----F----
-ELFSG-FL----KFFP-GP--HRRSQS-NLEFINAYIAD---NVEKHR----QSLDPNA
-PRDFID-----------IYLLRMEK---------EKGISG-TEFHHKNLI-LTVLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GCLIL
LKYPGVA-EKVQDEID---QVIGKD-RTPEIKDRAKMPYTEAVIYEIQRFSDLLPLG-VP
HCVT-QD--TSFRGYLI--PK---------------------------------------
-----------------------GT-E-VYP--LLSTV-LHDP-KYFKKPYDFD-----P
NHFLDAQGSLK--KNEAFIPFSS-------------------------------------
------------------------GKRI-CL--GEGIAR--MELFLFLTTILQ-NFSLRS
SMVP---ADIDLTP-RESGVG--------NVPP----T---------FQIQFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------L-REEE-AVNI----------

PF00067 // ENSGT00880000137861_0_Domain_2 (410, 1252)

-G----IVFS-
-NG--E-KWKQTRRFSLMVLRNM--GMGKRTIE--HRIQEEALCLVEA------LK-KPM
----GS-P----C------------------------D-PTFLLSYA----PCNVICSIV
FRNRFEYSDE-NF-LTLAKYFDENAKILST-----------PWI-----EL----Y----
-NAFPS-LL----HYLP-GS--HNTLFK-NMTEQRKFILE---KIKEHQ----ESLDLNN
-PQDFID-----------YFLIKME-K--------EKHNKQ-SEFTMDNLI-TTIWDVLT
AGI-ETTS-LTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IN---HVVGRN-RSPCMEDRSRMPYTDAVIHEIQRFIDLVPNN-LP
HAAA-QD--IKFREYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDG-KEFPNPEQFD-----P
GHFLDKSGNFK--KSDYFMAFS-AGK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLLLVSILQ-KFTLKP
LVDP---KNIDTAP-LLKGV-G-------SIPH----F---------YEVCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------IMKISERYGP-VFTIHLGP----R-RVVVLCGHDA
V---REALVDHAEE-FSG--RGEQATFNW----V-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLIEALRG-------TR
----GA-N----I------------------------D-PTFFLSRT----VCNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTST-----------SMG--Q---L----H----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFYMQNLL-MTALNLFI
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-QQPKFEDRVKMPYMEAVIHEIQRFGNVIPMS-LA
RRVN-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-RFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFFTTIMQ-NFRFKS
PQSP---KDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLLLC-------------------LSF-
-LLLFSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------DTS--K-SF----G--NL-SKVYGP-VFTVYFGM----K-PVVVLHGYEA
V---KEALIDNGEE-FSG--RGIFP---V-SQRT-SKEL-----------G----IIFS-
-NG--K-RWKEIRRFSLTTLRNF--GMGKRSIE--ERVQQEARCLVEE------LR-KNE
----AS-P----F------------------------D-PTFILGCA----PCNVICSVV
FQNRFDYKDE-TF-LTLMKRFNENFRILGS-----------PWI-----QV----C----
-NIFPL-FL----DYFP-GT--HNKLFK-NVALTKSYIEE---KIKEHQ----ASLDINN
-PRDFID-----------CFLIKMQ-Q--------EKDNQE-SEFTIENLV-STVADLFV
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSHMPYTDAVVHEIQRYINLVPAG-VP
HAVT-TD--IKFRNYLI--PK---------------------------------------
-----------------------GT-A-IMS--SLTSV-LYSD-KEFPNPTTFD-----P
GHFLDKNGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MEIFLFLTTILQ-NFNLKY
VGDI---KNLNTTA-ISNGM-V-------SLPP----L---------YQICLIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--TVLAF-------------------LV--
VLVLMSVW--KQR-KLSGKM

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISERYGP-VFTIHLGP----R-RIVVLCGQEA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-SG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLLEAFRK-------TN
----GA-L----I------------------------D-PTFYLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GS--QQQAFK-ELQGLEDFIAK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMLE---------EKKNPN-TEFYMKNLV-MTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKYEDRLKMPYTEAVIHEIQRFGDMIPMG-LA
RRVT-KD--TKFRDFLI--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPKDFN-----P
KHFLDDKGQFK--KNDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTNILQ-NFRFRS
AQAP---QDIDVSP-RLVGFA--------TIPP----N---------YTMSFLSR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQL-----DI-R-----
----------NIS--K-SF----S--NF-SKLYGP-VFTVYFGL----K-PTVVLHGYEA
L---KEALIDHGEE-FSG--RGALP---L-IERS-HKGH-----------G----IIFS-
-TG--K-RWKEMRRFSLLTLRNF--GMGKRSIE--DCVQKEARCIVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSIV
FQNRFQYEDK-NF-LTLMERFNENFRIAST-----------PWI-----QV----C----
-NIFPF-LI----DYFP-GT--HNKFLK-NGAFTKSYILE---KVKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFTVENLV-STVFDLFV
AGT-HTTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYMDAVLHEIQRYIDLIPNG-LL
HTVT-SD--IKFRNYLI--PK---------------------------------------
-----------------------GT-N-IVP--SLTSV-LYDD-KEFPNPEVFD-----P
GHFLDESGNFK--KSENFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
LTDL---KALNATP-TAKGL-V-------SMLP----S---------YQICFTPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (329, 1103)

FQKKYGD-VFTVYLGS----R-PIVMLCGPEA
I---REALVDQAEA-FSG--RGTIA---V-VEPV-FQGY----------G-----VVFA-
-NG--E-RWKALRRFSLATLRDF--GMGKRSVE--ERIQEEAQCMVEE------LR-KSQ
----GG-L----V------------------------D-PIFLFHSA----TANIICSIV
FGNRFDYKDP-QF-LRMLDLFYKSFSLISS-----------FSS-----QV----F----
-ELFSN-IL----KHFP-GS--HREIYK-NLQEINTFIGH---SVEKHR----ETLDPSS
-PRDFID-----------SFLLRMDK---------DKTDQN-TEFHHKNLI-MTLLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLFL
LKYPHIT-ERVQKEIE---QVIGSH-RQPALEDRTKMPYTEAVICEMQRFADLVPIG-VP
HVVT-KD--TVFRGFIL--PK---------------------------------------
-----------------------NT-E-IYP--ILSTA-LHDP-RHFEKPDTFN-----P
DHFLDANGALR--KNVAFMPFSM-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEFNST----LVL--FLLFL-------------------IT--
FMLML-----SK-KKHRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPV---PLPYIGNM-------HQV-----KI-N-----
----------DLI--K-SL----V---DLSKKYGP-MYTFYLGS----R-PTVVLCGYQI
L---KEALIDHAEE-FSG--RGEFP---A-VQMY-SKG----------NG-----IVYG-
-TG--E-RWRQLRRFAITTLKNF--GMGKRSLE--ERVKEEAQYLIAE------FR-NSE
----GE-P----F------------------------D-PTFGFSSA----GSNIICSLV
FGDRFDYRNP-EF-LNLLYLINNSWHLMSS-----------TWG-----QL----L----
-FVFPK-IM----QLIP-GP--HKKIYK-NYLKLGAFVAK---RLKMNK----ETLDPNN
-PRDFID-----------CFLIKIQ-Q--------EKKNPD-SHFNYETML-KTTVNVFF
AGT-ETVG-STLRYGFLILLKHPEVE----------------------------------
------------------------------------------------------------
-------EK-VQ----G---E---------------------------------------
--------------ID---KVIGRN-RSPCMDDRSKMPYTEAVIYEILRFADIVPMS-VP
HTVT-RD--IEFRGYTL--PK---------------------------------------
-----------------------GL-N-IMP--LICTS-QYDV-TKFKNPASFD-----P
AHFLDENMDFK--KNEGFMAFSA-GK----------------------------------
--------------------------RI-CV--GEGLAQ--MELFIFFTTILQ-NFKLKR
LMDP---KNIDITP-ESSGL-G-------NIPR----P---------YKLCLIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MALGG-A---FGI--FMVLF-------------------LSC-
-LLISLAW--KRTS-KRGML

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1102)

PPGPT---PIPFLGNL-------LQV-----RI-D-----
----------AIF--Q-SF----LK---LQKKYGS-VFTVYFGP----R-PVVVLYGHEA
V---KEALVDQADD-FSG--RGEMP---T-IEKN-FQGHG---------------LALS-
-NG--E-RWKVLRCFSLAILRNL--GMGKRTIE--ERIQEEAGYLLEE------IH-KVK
----GA-P----I------------------------D-PTFYLSRT----VSNVICSIV
FGKRFDYEDK-CF-QNLMKMINETFVEMSK-----------PWA-----Q-L---Y----
-DMFWG-VM----QYFP-GS--HNHLYD-LIEELKDFIAS---RVKLNE----ASFDPSN
-PRDFID-----------CFLIRMYQ---------DKSDPN-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLXXX-XLMMKYPEVE----------------------------------
------------------------------------------------------------
-------AK-VL----E---E---------------------------------------
--------------IN---QVIGSH-RKPAVEDRAKMPYTDAVIHEIQRLTDIVPLG-VP
HNVI-RD--THFRGYFL--PK---------------------------------------
-----------------------GT-D-VYP--LIGSV-LRDP-KYFRYPDAFY-----P
QHFLDEQGRFK--KNDAFVAFSS-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------PW--S-WF---

PF00067 // ENSGT00880000137861_0_Domain_2 (323, 1251)

-LR--QLRDKYGP-VFTVHLGP----R-PVVVLCGHEA
V---KEALVDQAEE-FSG--RGELA---S-LDRN-FNGTG---------------VALA-
-NG--E-RWRQLRRFSLTALRNF--GMGKQSIE--ERIQEEAQFLVEA------FR-ETQ
----GL-P----F------------------------D-PTFFLSRT----VSNVISSVV
FGRRFDYEDQ-TF-LSLLHKIHESLLEMST-----------PWA-----QVIYSST----
-DMFSC-VM----RYLP-GR--HNHIYS-LMEDLKAFIAE---KAQANL----ETLDPDN
-PRDFID-----------CFLIQMEK---------EKGNPS-SEFNMENLV-PTALNLFF
GGT-ETVS-STLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
-------EK-VH----Q---E---------------------------------------
--------------ID---RVIGRE-RLPSIEDRKRMPFTDAVVHEIQRVTNIVPLG-MP
HSVV-RD--THFRGFLL--PK---------------------------------------
-----------------------GT-N-VFP--LLGSV-LTDP-KYFHNPEKFN-----P
GHFLDANGCFK--KNEAFVPFAS-GK----------------------------------
--------------------------RV-CL--GEAMAR--MELFLYVVIILQ-NFSLKA
LVPP---EDIDLTP-QVSGF-A-------NIPP----E---------YRMCLVPRC----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDAFV--VLVFI-------------------LSC-
-LFLLSLW--RQSS-ERGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNF-------LQI-----DV-K-----
----------DIS--G-SL----T--NF-SKVYGP-VFTLYLGM----K-PTVVLHGYEA
V---KEALIDHGEE-FAG--RGSFP---V-AERV-NKGL-----------G----IVFS-
-NG--S-RWKETRRFSLMTLRNL--GMGKRSIE--DRVQEEAQCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FQNRFDYKDK-DF-LTFMKKLNENARILSS-----------PWF-----QV----C----
-NNFPL-LI----DYCP-GS--HHRITK-NINYIRSYLSE---KMKEHQ----ESLDVAN
-PRDFID-----------YYLIKLK-Q--------GNYNQQ-SEFSPENLA-TTVSDLFA
AGT-ETTS-TTLRYALLLLLKHPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---QVVGRH-RNPCMQDRSHMPYTDAMIHEVQRFIDLIPTN-LP
HAVT-CD--IKFRDYFI--PK---------------------------------------
-----------------------GT-T-IIT--SLSSV-LHDS-KEFPNPEVFD-----P
GHFLDKNGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RM-CA--GEGLAR--MELFLFLTTILQ-NFKLKS
LVHP---KDIDTTP-VLNGF-A-------SLPP----S---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELGG-A---VTI--FLALC-------------------LSC-
-LLVLIAW--KRMN-KAGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PIPFLGNL-------LQV-----RT-D-----
----------ATF--Q-SF----MK---LREKYGP-VFTVYMGP----R-PVVVLCGHEA
V---KEALVDQADE-FSG--RGELA---S-IERN-FQGHG---------------VALA-
-NG--E-RWRILRRFSLTILRDF--GMGKRRIE--ERIQEEASYLLEE------FR-KTK
----GA-P----I------------------------D-PTFLLSRT----VSNVISSVV
FGSRFDYEDK-QF-LNLLRLINESFIEMST-----------PWA-----Q-L---Y----
-DMYSG-IM----QYLP-GR--HNHIYY-LIEELKDFIAS---RVKINE----ASFDPQN
-PRDFID-----------CFLIKMHQ---------DKNNPR-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
-------AR-IH----E---E---------------------------------------
--------------IN---QVIGPH-RLPSVDDRVKMPYTDAVIHEIQRLVDIVPMG-VP
HNVI-RD--TQFRGYLL--PK---------------------------------------
-----------------------GT-D-VFP--LLGSV-LKDP-KYFRYPEAFY-----P
QHFLDEQGRFK--KNEAFVPFSS-GK----------------------------------
--------------------------RI-CL--GEAMAR--MELFLYFTSILQ-NFSLRS
LVPP---ADIDITP-KLSGF-G-------NIPP----T---------YELCLVAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--IILIAW--KRT-NKGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1238)

PPGPT---PIPFLGNL-------PQV-----RTDA-----
-----------TF--Q-S-------FLKLSEKHGP-MFTVYMGP----R-PIVVLCGREA
V---KEALVDQAEE-LSG--RGEQATFDW----L-FKG--------------YDM-AFS-
-NG--Q-RTKQLQHYCMTTLRDF--SMGKRGIE--ECIQEEVGFLTEKFRG-------TR
----GA-I----I------------------------D-PTFFLSRT----VSNVISSVV
FGDRFDYENK-EL-LSLLRMMKGSLAFTAT-----------STG-----QL----Y----
-EMFYS-VM----KHLP-GP--QQQAFR-ELQGLDDFIAK---KVVHNQ----HTLDPNY
-PRDFID-----------SFLIRMQE---------EQKNPN-MAFCMKNLV-LTTLNLFL
AGT-ETFS-MTLRCGILLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEIY---QVIGKN-RHPRFEDRAKMSYTKAVIHEIERFGDLSPMG-LA
HRFT------KFQDFFL--PKGN-------------------------------------
--------------------------E-VFP--MLGSV-LADS-KFFSKPRDFA-----P
QHFMDEKGQFK--KSDAFVPFSI-GKRCR----PLLTPT---------------------
------------------------------------------GLFLFLITIMQ-NFRFKS
LQSP---EDIDVSP-KHVGLT--------RIPP----Y---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--VLVLG-------------------LCC-
-LLLLSIW--KQNS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PFPIIGNI-------LQI-----DA-K-----
----------DIS--K-SL----T--KF-SECYGP-VFTVYLGM----K-PTVVLHGYEA
V---KEALVDLGEE-FAG--RGSVP---I-LEKV-SKGL----------G-----IAFS-
-NA--K-TWKEMRRFSLMTLRNF--GMGKRSIE--DRIQEEARCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSVI
FHNRFDYKDE-EF-LKLMESLNENVRILSS-----------PWL-----QV----Y----
-NNFPA-LL----DYFP-GI--HKTLLK-NADYIKNFIME---KVKEHQ----KLLDVNN
-PRDFID-----------CFLIKME-Q-----------ENN-LEFTLESLV-IAVSDLFG
AGT-ETTS-TTLRYSLLLLLKHPEVA----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------IE---RVIGRH-RSPCMQDRSRMPYTDAVIHEIQRFIDLLPTN-LP
HAVT-RD--VRFRNYFI--PK---------------------------------------
-----------------------GT-D-IIT--SLTSV-LHDE-KAFPNPKVFD-----P
GHFLDESGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTSILQ-NFKLQS
LVEP---KDLDITA-VVNGF-V-------SVPP----S---------YQLCFIPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--VLVLC-------------------LSC-
-LLLLSLW--IQSS-RNGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPILGNI-------LQL-----DV-K-----
----------NIS--K-SL----S--KL-SKVYGP-VFTVYFGM----K-PTVVLHGYQA
V---KEALIDRGED-FSG--RGSFP---L-AERI-NKGY-----------G----IVFS-
-NG--K-TWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FHNRFDYKDQ-TF-LNIMKRFNENIRIASS-----------PWI-----QI----C----
-NSFPV-LI----DYFP-GS--HNKVIK-NNANLKDYILE---KTKEHQ----ASLDMNN
-PRDFID-----------CFLIKME-Q--------EKHKQE-SEFTVENLL-ATISNLFG
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPCIQDRSRMPYTDAVVHEIQRYIDLIPTN-VP
HAVT-HD--IKFRNYVI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDD-KQFPNPEVFD-----P
GHFLDESGNFK--KTEYFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTTILQ-NFTLKS
LVDP---KDIDTTP-IVNGL-A-------SVPP----P---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--FLVLS-------------------LSC-
-LLLLSLW--RQHS-ARRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQM-----DL-K-----
----------DIS--K-SF----S--NF-SKVYGP-VFTLYIGT----K-PTVVLHGYEA
V---KEALIDLGEE-FAG--RGSFP---V-AERM-NKDL----------GG----IFLS-
-SG--N-RWKEMRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGAA----PCNVICSII
FQNRFEYTDQ-DF-LTFLKLLNEGINILSS-----------PWI-----QV----C----
-NNFPV-LI----DYFP-GS--HKTFME-DMTCIQNFISE---KVKEHQ----QSLDMNN
-PRNFID-----------CFLIKME-Q--------EKHNQQ-SEFTLENLK-YTVGDLFA
AGT-ETTS-TTLRYGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------IE---HVIGRH-RSPCMQDRSRMPYTDAVIHEIQRFIDLVPTS-LP
RAVT-RD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDD-KEFPNPESFD-----P
GHFLDKSGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFRLKP
LVDP---KDINITP-VVNGF-A-------SVPP----P---------YQLCLIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--VLV---------------------LCC-
-LLLLSLW--IQSS-QKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPILGNI-------L-L-----DV-K-----
----------NIS--K-SL----N--NL-S-EVGP-VFTVYLGM----K-PTVVVLGYKA
M---KET--DLGEG-FSG--RGSHP---V-IERT-GKGL-----------G----IVFI-
-NG--K-RWKKIRRFSLMTLWNF--GMGKRSIE--DHVQEEAHCFVEE------LR-KTS
----AS-P----C------------------------D-PAFLLSCA----PCNVICSII
FRNRFEYSDE-EF-LTMIKYINENARLVST-----------SWI-----EL----Y----
-NAFPS-LI----HYLP-GS--HNTIFR-NIIEQRKFIFE---NIKKHQ----ESLDLSN
-PQDFID-----------YFLIKME-K--------EKHNQK-LAYTFENLA-FTISDLFG
AGT-ETTS-TTLRYGLLLLLKHPEAT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPFIQDRSRMPYMDAVVHEIQRYIDLVPTN-IP
HAVT-CD--IKFRNYLI--LK---------------------------------------
-----------------------GI-D---M--SLTSV-LHDD-KEFPNPEVFD-----L
GHFLDESGNFK--KSDYFMAFS-AGK----------------------------------
--------------------------RI-CV--GESLAR--MELFLFLTTILQ-NFTLKS
VVDS---KDIDITP-VISGL-A-------SVPP----P---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------METSVL------L--LLTLL--------------------VGF
VLLLV--R--GHPK-GRGYL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQM-----DR-G-----
----------GLL--N-SF----M--K-LREKYGD-VFTMHLGP----R-PVVMLYGTEA
I---REALVDQAEA-FSG--RATIA---V-VRPV-VKDY----------G-----VIFA-
-NG--E-RWKTLRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----M------------------------D-PTFLFQCI----TANIICFIV
FGERFDYKDR-QF-LRLLDLFYRSFSLISS-----------FSS-----QM----F----
-ELFSG-FL----KYFP-GA--HREISR-NLREILDFIGQ---SVERHR----ATLDPSN
-PRDFID-----------TYLLRMEK---------EKSNQH-TEFHHENLI-ISVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVIGSH-RLPNLDDRTKMPYTEAVIHEIQRFSDLIPIG-VP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-RYFAQPDTFN-----P
DHFLDANGALK--KNEAFMPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PVAP---KDIDLNP-KETGFG--------KVPP----A---------YQICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--TVLAF-------------------LV--
ILVLMSVW--KQR-ELSGKM

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEE-----
-----------IY--N-S-------LMKIRERYGP-VFTVHLGP----RRRIVILCGQEA
V---KEALVDHALE-FSG--RGENATFDW----L-FKG--------------YGV-AFS-
-PW--E-RSKPLRRFSIATLRDF--GMGKRGIE--ERIQEEADYLLEALQK-------TN
----GA-L----I------------------------D-PTFYLSRT----VSNVMSSIV
FGNRFDYEDK-EF-LSLLKMMTESFQFTAS-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQKAFK-ELQGLEDFITK---KVEQHQ----STLDSNS
-PRDFID-----------SFLIHMQA---------EKKNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEIN---QVIGRN-RQPKYEDRMKMPYTEAVIHEIQRFADLIPMG-LP
RRVT-KD--TKFRDFLI--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LNDP-KFFSNPKDFN-----P
KHFLDDNGQFK--KNDAFIPFSL-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFLTNILQ-NFHLRS
SQAP---RDIDVSP-KMVGFG--------TIPP----N---------YTMSFLSH-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAVLGIT-----V--ALLVW-------------------IAT-
-LLLVSIW--KQIY-RSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PIPFFGNI-------FQL-----DL-K-----
----------DIP--K-SF----T---KLAKRFGP-VFTLHLGH----R-RIVVLHGYKA
V---KEVLLNHKNE-FSG--RGDIPVFQE----YKNKG-----------------IIFN-
-NG--P-TWKDVRRFSLSILRDW--GMGKQGNE--ARIQREAHFLVEE------LK-KTK
----GQ-P----F------------------------D-PTFLIGCA----PCNVIADIL
FNKRFDYNDK-KC-LELMSLFNENFYLLST-----------PWI-----QA----Y----
-NYFSD-YL----QYLP-GS--HRKIMK-NVSEIRQYTLE---KAKEHL----KSLDINC
-ARDVTD-----------CLLIEMEK---------EKHSQE-PMYTMENIS-VTLADLFF
AGT-ETTS-TTLRYGLLILMKYPEIE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RAPAVRDRMNMPYMDAVVHEIQRFINLVPSN-LP
HEAT-RD--TVFQGYVI--PK---------------------------------------
-----------------------GT-V-VIP--TLDSL-LFDN-YEFPDPETFK-----P
EHFLNENGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLLLSAILQ-HFNLKS
LVDP---KDIDLSP-VTIGF-G-------SIPR----E---------FKLCVIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------LAL-------------------CHF-
-LIF-VSL--IQGFQR-RKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1212)

PPGPT---SLPFIGNI-------LQM-----DI-K-----
----------NIC--N-I---------LLAEKYGP-IYTLYFGT----Q-PIVVLHGYNV
T---KEALIDQGDV-FME--RGDVP---I-FNDL-TKG----------KG-----VIFS-
-HG--E-RWKQIRRFSLMTLRNF--GMGKRTIE--ERVQEEAQCLVKE------LR-KTK
----GQ-P----T------------------------D-PTFILGCA----PCNVICSIL
FRDRFKYSDE-KF-LHLMRLLNENFRLFSK-----------PWT-----QV----Y----
-NSFPS-LV----HYLP-GS--HHKAIK-NSNF--SIYFE---EMKEHQ----RTLDCSY
-PWDSID-----------CFLMKME-Q--------EKQQLQ-SEFTIENLV-CTASDLFG
AGT-KTTR-TTVRYGLLLLLKHPEIT----------------------------------
------------------------------------------------------------
-------GK-IH----E---E---------------------------------------
--------------ID---CVIGRN-RSPCMEDRNKMPYTNAVVHEIQRYIDLIPTN-LP
HAVT-QD--VQFRQYLI--PK---------------------------------------
-----------------------GT-T-IFP--LLFPV-LHEN-KEFPKPDQFD-----P
QHFLDKSEKFK--KSDYFMPFSL-GK----------------------------------
---------------------------S-CL--GEGLAR--MELFLFFTTIL--NFTLKS
VGDP---NEISI------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------K-EF-

PF00067 // ENSGT00880000137861_0_Domain_2 (555, 1252)

LSLLRMMLGSFQFTAT-----------STG-----QL----Y----
-XXXXX-XX----XXXX-XX--XXXXXX-XXXXXXXXXXX---XXXXXX----XXXXXXX
-XXXXXX-----------XXXXXXXX---------EQKNPN-TEFYMKLV--TTALNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRYGDMIPMS-LA
RRVI-KD--TKFRDFLI--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPQDFN-----P
QHFLDEKGQFK--KNDAFMPFSV-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTAIMQ-NFRFKS
PQSP---QDIDVTP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVLGV--FLGLV-------------------LAC-
-LLLLSLW--RQNS-QRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQV-----DL-K-----
----------NIS--K-SL----R--DL-SKVYGP-VFTLYLGR----K-PAVVLLGYEA
V---KEAMVDHGEE-FAG--RGSFP---V-ADKI-GQGF-----------G----IVFS-
-SG--K-IWKTMRRFSLVTLRNF--GMGQRSIE--ERVQEEARYMVGE------LR-KTN
----GS-P----C------------------------N-PTFILGCG----PCNVICSIV
FQNRFDYKDK-EF-LNFMHVLNENVEILSS-----------PWM-----QI----C----
-NNFPF-MI----DYLP-GK--HRKLLE-NFTFLKHYFSA---KATQHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKNNPK-TEFIRENLI-FSASDLFA
AGT-ETTS-TTLRYSLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----K---E---------------------------------------
--------------ID---HVIGRN-RSPCMQDRSHMPYTDAVLHEIQRYIDLLPTS-LP
HATT-CD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIA--SLSSV-LYDD-KEFPNPEKFD-----P
GHFLDENGKFK--KSDYFFPFST-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
PVDL---KDLDITP-VANGF-V-------SVPP----E---------FQICFTPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------PSSAGPFL--L-----ILV--L--F-----------------------L
LLLL--LL--FRRGHPPARLPPGPR---ALPILGCL-------PQM-----WG-V-----
----------PLL--D-FL----L---KVNGALTGPPGCGGMGSLSPPP-PPLPPTGASG
S---GKTEDGIART-LSG--SA--X---L-PPGP

PF00067 // ENSGT00880000137861_0_Domain_2 (395, 1165)

-RLGP----------G-----ISFS-
-QG--E-RWRTLRRFSVATLRDL--GMGRRGIE--ERVQEEVRC-LLE-----EFR-KTR
----GH-P----F------------------------D-PTFPLRRS----ISNVICSVV
FGRRFDYADP-EF-GTLLRLLNDNLRRVDS-----------VSV-----RL----Y----
-SLFPG-LL----RHLP-GP--HNLLFE-VFEEQKRFVAR---IVKEHE----ASLDPAE
-PRDFMD-----------AFLIRMQQ---------DRKNP-LSEFHLENLL-VTALDLFF
AGT-ETTS-TTLKYGLLLLLKHPQIT----------------------------------
------------------------------------------------------------
-------ER-VQ----E---E---------------------------------------
--------------VD---SVIGQN-RRPALEDRARMPYTDAVIHEIQRFIDIMPLG-VP
HAVT-RD--TCFQGYTI--PKGT-------------------------------------
--------------------------M-VFP--LLHSV-LHDP-DHFPDPAVFE-----P
KRFLTEDGRFQ--RNAAFLPFSA-------------------------------------
------------------------GE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------ML-DSGEKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPVIGNY-------LQL-----NTKD-----
-----------TR-------------LGDGERYGS-VFTIHLGL----C-RVVVLYGYDA
V---KGALVDQAEE-FSD--RGEQSTCHT----L-VKG--------------YGV-TFS-
-NG--E-RSKRLWRFTIATLRDWQTGVGKHGVE--ECTQEEAACLVKILQD-------TR
----GA-P----I------------------------D-PTFYLSKT----VSDVISSIV
FGDRFNYEDK-EF-LSLLHMMMQIN------------------------------L----
-QLHPL-VM----KYLP-GP--QQGIFK-NMRKLEDFIVK---KVAQNQ----RTLDPSS
-PRDFID-----------TFLIQMYE------------NPN-TEFYMKNLV-MTTLSLFF
AGS-ETVS-STLRYSFLLLLKHLDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---LVIGRN-RQPQFEDHLKMPYTEAVIHEIQRSANFTPLG-IP
RRVT-KD--TTFHSLFL--PKGT-------------------------------------
--------------------------E-VFP--ILGSL-MTDP-KFFPSPQDFN-----P
QHFLDDKGQLK--KNDAFVPFSI-------------------------------------
------------------------GKKY-CL--GDGLSR--MELLLFLTTIIQ-NFCFKS
PKTL---QNINVSQ-RPMGFT--------RIIP----S---------YTISFLPL-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVV------L--LLAVL--------------------TGL
LLLLA--R--DHPK-AHGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1056)

PPGPR---PLAFLGNI-------LQM-----DR-R-----
----------GLL--K-SF----L--R-FREKYGD-VFTVYLGP----R-PVVMLCGIEA
I---REALVDQAEA-FSG--RGRVS---T-VERI-FQGH----------G-----VIFA-
-NG--E-RWKLLRRFSLATMKNF--GMGKRSIE--ERIQEECQCVVEE------LQ-KTQ
----GA-F----Q------------------------N-PTFLFHSM----TANIICSIV
FGTRFSYKDP-KF-LRLLDLFYQNFTLLSS-----------FSS-----QV----F----
-ELFYN-FL----KYFP-GT--HRQIYK-NTQEIIAFIED---AVEKHR----ETLDPST
-PRDFID-----------AYLIRMDK---------EKSDPN-SEFHHRNLI-CTVLSLFF
AGT-ETTS-STLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFQLL
LKYPHVT-ERVHKEID---QVIGPH-RLPSLDDRVKMPYTDAVIHEIQRFSDLFPIG-IP
HMVT-KD--THFRGYFM--PK---------------------------------------
-----------------------GT-E-VYP--LLHS-----------------------
-------------KTEAFIPFSM-------------------------------------
------------------------GKRI-CL--GEGIAH--MELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-QESGIG--------RVPP----V---------YQISFRSLRGD--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------METSVL------L--LLALL--------------------VGF
VLLLV--R--GHPK-GRGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQM-----DR-G-----
----------GLL--N-SF----M--K-LREKYGD-VFTMHLGP----R-PVVMLYGTEA
I---REALVDQAEA-FSG--RGTIA---V-VRPV-FKDY----------G-----VVFA-
-NG--E-RWKTLRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFDYKDR-QF-LRLLDLFYRSFSLISS-----------FSS-----QM----F----
-ELFSG-FL----KYFP-GT--HRQISK-NLQEILDFIGQ---SVEKHR----ATLDPSN
-PRDFID-----------TYLLRMEK---------EKSNKD-TEFHHENLM-LSVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVIGSH-RLPNLDDRTKMPYTEAVIHEIQRFSDLIPIG-VP
HRVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDQ-RYFAQPDTFN-----P
DHFLDANGALK--KNEAFMPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSLSS
PLAP---KDIDLSP-KESGFG--------KVPP----T---------YQICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--VLGLC-------------------LSC-
-MLLLSLW--KQSS-EKGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1057)

PPGPT---PFPILGNV-------LQL-----GF-K-----
----------DIS--K-SL----T--RL-SEVYGP-VFAVFLGL----R-PTVVICGYDA
V---KEALVDLGEE-FSG--RI-FP---V-TAKV-KKGF----------G-----IIFS-
-NR--K-RWKETRRFSLMTLRNF--GMGKKSIE--ERVQEEACCLVEE------LR-KMS
----GS-P----C------------------------D-PTFILGAA----PCNVICSVI
FQNCFDYRDP-NF-LAFIDKFNENFKILNS-----------PWV-----QV----C----
-NTFPI-LL----DWFP-GS--HRKMIS-NSTYVANYDLE---KIKEHQ----ESLDITN
-PRDFID-----------CFLIKME-Q--------EKHNQQ-SEFTVENLM-TTVLDVFA
AGT-ETVS-TTLRYGLLLLMKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---K---------------------------------------
--------------IE---CVIGRH-RSPSMQDRSRMPYTDAVIHEIQRYVNLVPNN-VP
WATT-CN--VAFRSYLI--PK---------------------------------------
-----------------------AS-A-VAV--CGYKN-LYN------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------VDPFV--VLVLC-------------------VSC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQL-----DI-R-----
----------NIS--K-SF----S--NF-SKLYGP-VFTVYFGL----K-PTVVLHGYEA
L---KEALIDHGEE-FSE--RGALP---L-IERS-QKGH-----------G----IIFS-
-TG--K-RWKEMRRFSLLTLRNF--GMGKRSIE--DCVQKEARCIVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSIV
FQNRFQYEDK-NF-LTLMERFNENFRIAST-----------PWI-----QV----C----
-NIFPF-LI----DYFP-GT--HNKFLK-NGAFTKSYILE---KVKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFTVENLV-STVFDLFV
AGT-HTTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYMDAVLHEIQRYIDLIPNG-LL
HTVT-SD--IKFRNYLI--PK---------------------------------------
-----------------------GT-N-IVP--SLTSV-LYDD-KEFPNPEVFD-----P
GHFLDESGNFK--KSENFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
LTDL---KALNATP-TAKGL-V-------SMLP----S---------YQICFTPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLAFF--------------------AGF
LLLLV--R--GHPK-ARGHLPPGPR---PLPFLGNL-------LQM-----DR-R-----
----------GLL--N-SF----M--R-LRDKYGD-VFTVHLGP----R-PVVMLYGTEA
I---REALVDQAEA-FSG--RGTIA---V-------------------------------
--------------------------R

PF00067 // ENSGT00880000137861_0_Domain_2 (448, 981)

GKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PKFLFQCI----TANIICSIV
FGERFDYKDR-QF-LRLLELFYRSFSLISS-----------FSS-----QV----F----
-ELFSG-FL----KYFP-GT--HKQIYR-NLKEILDYIDH---SVDKHR----ATLDASN
-PRDFID-----------TYLLRMEK---------EKSNSH-TEFHHQNLI-ISVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEIE---EVIGSH-RLPTLDDRTKMPYTDAVIHEIQRLSDVVPIG-VP
HKVT-KDT-LFR-GYLL--PKVRPSNLLIHCNG---------------------------
---QSCLG-LGM------------------------------------------------
---GQSEGCTLPWGSHGSSSVPT-------------------------------------
------------------------GKRI-CL--GEGIAR--HELFLFFTTLLQ-NFSLSS
PVDP---KDIDLSP-KESGIG--------RVPP----E---------YQICFLSR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VIVLMSVW--QQR-NSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------IMKISERYGP-VFTLHLGT----R-RVVVLCGHDA
V---KEALVDQAEE-FSG--RGEQATFNW----V-FKG--------------YGV-VFS-
-NG--E-RAKQLRRFAIATLRDF--GVGKRGIE--ERIQEEAGFLTVALRD-------TH
----GA-N----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLGMMLAIFQFTST-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFYLKNLM-MTTLNLFI
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRVKMPYMEAVIHEIQRFGDVIPMG-LA
RRVN-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-RFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFFTTIMQ-NFRFKS
PQSP---KDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGVI-------VYV-----EA-ITITIL
FIYEIQKYLKLCL--T

PF00067 // ENSGT00880000137861_0_Domain_2 (317, 1252)

-KM------STF-SKVYGP-VFTLYLGL----K-PSVVLHGYDA
V---KEALVDLGEE-FAG--RGSFP---L-SEKV-NKDF-----------G----ILFS-
-NG--K-RWKELRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FQKRFEYKDQ-NF-LNLMEKFNENLRIISS-----------PWI-----QV----C----
-SIFPA-LM----DYLP-GS--HNTIIK-NFDYVKSYVLE---KIKEHQ----ESLDVNN
-PRDFID-----------CFLIKMK-E--------EKNNQQ-SEFTIENLL-TTVTDLFG
AGT-ETTS-TTMRYGLLLLLKHTNIT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---QVIGRH-RSPCMQDRRCMPYTEAVLHEIQRYIDLIPTS-VP
HAVT-CD--VKFRNYFI--PK---------------------------------------
-----------------------GT-R-IIT--SLTSV-LHDD-KEFPNPEVFD-----P
GHFLDESGNFK--KSDYFMPFSS-GK----------------------------------
--------------------------RI-CL--GEGLAR--MELFLFLTTILQ-NFKLKP
VIDP---KDIDTTP-IANAF-G-------RVPP----L---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-MPKRK-----ILICECCIKC---LECLI-------------------------------
---------------IPVSVRR-VSMDPFV--VLVLC-------------------LSF-
-LLVLSLW--RQRS-ARGNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNY-------HLI-----DM-K-----
----------DIG--Q-CL----T--NF-SKTYGP-VFTLYFGS----Q-PIVVLHGYEA
I---KEALIDHGEE-FSG--RGRIP---V-FDKV-STGK----------G-----IGFS-
-HG--N-VWKATRVFTVNTLRNL--GMGKRTIE--NKVQEEAQWLMKE------LK-KTN
----GS-P----C------------------------D-PQFIIGCA----PCNVICSIV
FQNRFDYKDK-DF-LSLIGKVNECTEILSS-----------PGC-----QI----F----
-NAVPI-LI----DYCP-GS--HNKLFK-NHTWIKSYLLG---KIKEHE----ESLDVTN
-PRDFID-----------YFLIQRR-Q--------KNGIEH-MDYTIEHLA-TLVTDLVF
GGT-ETLS-STMRFALLLLMKHTHIT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---NVIGRH-RSPCMQDRNHMPYTNAMVHEVQRYIDLGPNG-VV
HEVT-CD--TKFRNYFI--PK---------------------------------------
-----------------------GT-Q-VMT--SLTSV-LHDS-TEFPNPEVFD-----P
GHFLDDNGNFK--KSDYFVPFSA-------------------------------------
------------------------GKRI-CV--GESLAR--MELFLFLTTILQ-NFKLKP
LVDP---KDIDMTP-KHSGF-S-------KIPP----N---------FQMCFIPVE----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------M----E

PF00067 // ENSGT00880000137861_0_Domain_2 (350, 1252)

-RVVVLHGYNI
V---KEALIDKGDI-FME--RGNVP---I-FEDA-IKG----------QG-----VIFS-
-RG--E-RWKQLRRFSLMTLRNF--GMGKRSIE--ERVQEEAQCLVEE------LR-KTK
----GQ-P----N------------------------D-PTFILGCA----PCNVICSIL
FRDRFKYKDE-KF-LYLMSLLNENFQLFTK-----------PWI-----QL----Y----
-NFLPA-FR----VHLP-GK--HKQLFK-NVEELKCFILE---RVKEHQ----EILDPNN
-PQDYID-----------CYLSKMQ-Q--------EKNNPQ-SEFDVENLI-MTGVDLFS
AGT-ETTS-STLRYGLLLILKHPEVQ----------------------------------
------------------------------------------------------------
-------AK-IH----E---E---------------------------------------
--------------IN---RVIGHN-RIPSIKDRQDMPYMDAVVHEVQRFIDLLPLN-LP
HAVN-QD--IQLQQYTI--PK---------------------------------------
-----------------------GT-N-VFP--LLSPV-LRDS-KEFSNPDKFD-----P
QHFLDKNGSFK--KSDCFMPFSA-GK----------------------------------
--------------------------RA-CL--GEGLAR--MELFLFLTTILQ-NFTLKP
VGDP---NEISVKN-NHVGF-T-------NVPP----Y---------YQLCFLPHKA---
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSC-
-LLLLSIW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNI-------LQI-----DI-K-----
----------DVS--K-SL----T--NL-SKIYGP-VFTLYFGL----E-RMVVLHGYEV
V---KEALIDLGEE-FSG--RGHFP---L-AERA-NRGF-----------G----IVFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FQKRFDYKDQ-QF-LNLMEKLNENIRIVST-----------PWI-----QI----C----
-NNFPT-II----DYFP-GT--HNKLLK-NLAFMESDILE---KVKEHQ----ESMDINN
-PRDFID-----------CFLIKME-K--------EKQNQQ-SEFTIENLV-ITAADLLG
AGT-ETTS-TTLRYALLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRN-RSPCMQDRGHMPYTDAVVHEVQRYIDLIPTS-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDN-KEFPNPEMFD-----P
RHFLDEGGNFK--KSNYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTFILQ-NFNLKS
LIDP---KDLDTTP-VVNGF-A-------SVPP----F---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDSVGT----TVL--FLLLA-------------------GIYL
LLS-F------G-FRSKGRLGR

PF00067 // ENSGT00880000137861_0_Domain_2 (263, 1250)

APV-----------------------------------
------------T--S-FH----P---QLSKEYGS-MYTVYLGP----R-RVVVLSGYQT
V---KEALVDQGEE-FSG--RGDYP---V-FFNF-TKGN----------G-----IAFS-
-NG--E-RWKALRKFSVQILRNF--GMGKRSIE--ERILEESSFLLES------LQ-NTQ
----GE-P----F------------------------D-PVFVLSRS----VSNIICSVI
FGHRFDYSDE-RL-LAIIRFINDNFQIMSS-----------PWG-----EL----Y----
-NIFPG-LL----DWLPVGS--HRRMFQ-NFRGMKDLIAR---SIREHQ----ATLDPDN
-PRDFID-----------CFLTKMA-Q--------EKKDPL-THFQMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFLILMKYPKIQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---AVVGRS-RQPTLEDRAAMPYTDAVIHEVQRFADVIPMN-LP
HRVI-KD--TAFRGFLI--PK---------------------------------------
-----------------------VP-T-E--------R-ETET-ERFKTPQEFN-----P
EHFLDANQSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GEPLAK--MELFLYFTAILQ-RFTLQP
LGAP---EDIDLTP-LSSGL-G-------NVPR----P---------FKLRVLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLALL--------------------VGF
LLLLA--R--GHPK-SRGNF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQM-----DR-G-----
----------GLL--K-SF----I--Q-LREKYGD-VFTVHLGP----R-PVVMLCGTDT
I---REALVGQAEA-FSG--RGTVA---V-VEPT-FKEY----------G-----VIFA-
-NG--E-RWKTLRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFEYTDR-QF-LRLLELFYQTFSLISS-----------FSS-----QM----F----
-ELFSG-FL----KYFP-GA--HRQISK-NLQELLDYIGH---SVEKHR----ATLDPSV
-PRDFID-----------IYLLRMEK---------EKSNQH-TEFHHQNLM-MSVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVIGSH-RLPTLDDRTKMPYTDAVIHEIQRFSDLIPIG-VP
HRVT-KD--TMFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-QYFEQPDSFN-----P
DHFLDANGALK--KSEAFLPFST-------------------------------------
------------------------GKRI-CL--GESIAR--NELFLFFTSILQ-NFSVAS
HVAP---KDIDLTP-KESGIG--------KIPP----T---------YQICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLTV--VLVLG-------------------LSC-
-LLLLSLW--RQNS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNF-------LQI-----DV-K-----
----------DIR--Q-SL----T--NL-SKVYGP-VFTLYLGT----E-PTVVLHGYEA
V---KEALIDHAEE-FSG--RGRHP---V-AEKS-NKGL-----------G----IVFS-
-NG--N-RWKEIRRFTLMTLRNL--GMGKRNIE--DRVQEEAQCLVEE------LR-KTN
----GS-P----C------------------------D-PTNILSCV----PCNVICSII
FQDRFDYNDQ-EF-LDLMERLNDNIQILSS-----------PWI-----QV----C----
-NNFPF-LI----NYCP-GS--HNRILE-HMNYMEFYVMK---KIKEHQ----ESLDVTN
-PQDFID-----------YYLIKRS-Q--------ENHNQS-SEFTLENLA-MTVVDLFG
AGT-DTTS-TTLRYALLLLLKHPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVVGRH-RSPCMQDRSSMPYTDAMVHEVQRYIDLIPTN-LP
HAVT-SD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VLT--SLSSV-LKDS-KEFSNPEKFD-----P
AHFLDEKGNFK--KSDYFLPFSA-GK----------------------------------
--------------------------RM-CA--GEGLAR--MELFLILTTILQ-NFKLKP
LTHP---KDIDITP-VSSGF-A-------SLPP----P---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----A

PF00067 // ENSGT00880000137861_0_Domain_2 (487, 1103)

-A----I------------------------D-PTFFLSRA----VSNVICSIV
FGDRFEFEDK-QF-LSLLRMMQGSFQFTAT-----------SMG--Q---L----F----
-EMFSG-VM----KLLP-GP--QQQAFK-ELQGLEDFITD---KVQENQ----ATLDPKS
-PRNFID-----------SFLIKMQE---------EKKNPN-AEFDMRNLV-STTLNLFF
GGT-ETVS-TTLRYGFLVLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---RVIGQN-RPPKFEDKAKMPYTEAVIHEIQRFAHIIPMG-VP
RRVT-KD--TKFRGYLI--PKGT-------------------------------------
--------------------------E-VFP--MLGSA-LWDT-NFFACPEAFN-----P
QHFLDEEGQFK--KSDAFVPFSI-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELGG-A---FTI--FLALC-------------------LSC-
-LIILIAW--KRID-RGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PIPFLGNL-------LQV-----RT-E-----
----------GTF--Q-SL----MK---LHEKYGP-VFTVYMGP----R-PVVVLCGHEA
V---KEALVDQADD-FSG--RGEIA---S-IERN-FQGYG---------------VALA-
-NG--D-RWRILRRFSLSILRDF--GMGKRSIE--ERIQEEAGYLLKE------FR-KTK
----GA-P----I------------------------E-PTFFLSRT----VSNVISSVV
FGSRFDYEDK-QF-LNLLQLINESFIEMSI-----------PWA-----Q-L---Y----
-DMYSV-VM----QYFP-GR--HNRIYY-LIEKLKDFIAS---RVKINE----ASLDPQN
-PRDFID-----------CFLIKMHQ---------EKNNPH-TEFNIKNLV-LTTLNLFF
AGT-ETVS-STLRYGFLLLMKYPEVE----------------------------------
------------------------------------------------------------
-------TK-IY----E---E---------------------------------------
--------------IN---QVIGPH-RIPSVDDRSKMPYTDAVIHEIQRLTDIVPMG-VP
HIVI-RD--TQFRGYCL--PK---------------------------------------
-----------------------GT-D-VYP--LLGSV-LRDP-KYFRYPDAFY-----P
QHFLDEQGRFK--KNEAFVAFSS-GK----------------------------------
--------------------------RV-CL--GESMAR--MELFLYFTSILQ-NFSLHS
LVPP---ADIDVTP-RISGF-G-------NIPP----I---------YKLCLKAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----VV--ALLAC-------------------LS--
VMVLMSVW--RRR-KLLGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISKRYGP-VFTIHLGP----R-RIVVLCGQDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIQAFRD-------TR
----GA-F----I------------------------D-PTFYLSRT----VSNVISSIV
FGDRFEYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFITK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMLE---------EKQNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDMIPMG-LA
RRVT-KD--TKFRDFLI--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPRDFY-----P
QHFLDENGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTIMQ-NFRFKS
PQVP---KEIDVSP-KHVGFA--------TIPP----N---------YTMSFLLR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----E-P----F-----------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (517, 684)

-D-PTFVLSRS----GSNIICSVL
FGSRFDYDDE-RL-LTIIRLTNDNFQIMSS-----------PRG-----EV----S----
-QLSPA-G----------------MGCG-NFKCLRDLIAH---CVHDHQ----ASLDPRS
-SRDFID-----------CFLTKMA-----------------------------------
----ETVG-TMLRHAFLALMKYPKVQ----------------------------------
------------------------------------------------------------
-------D---E----E---E---------------------------------------
--------------ID---LMVGHV-RLPALKDRAAMPYTDMVIHEVQRFADITPMN-LP
HRVT-RD--TAFHGFLI--PKGT-------------------------------------
--------------------------S-IIT--LLNTV-HYDP-SQILTPQEFN-----L
EHFLDANQSFK--KSPAFMPFSA-------------------------------------
------------------------GRCL-CL--GRSLVR--MELFLYLSAALQS-FSRQP
LGAP---EDIDLTP-LSSGLA--------SLPR----P---------FQLCMCPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MC--N-S-------LMKISERYGP-VFTIHLGP----R-RVVVLCGYDA
V---KEALVDQAEE-FSG--RGEQATFDW----V-FKG--------------YGV-VFS-
-NG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLIEALRD-------TH
----GA-N----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLGMMLASFQFTST-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----HTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFYLKNLM-MTTLNLFI
AGT-ETVS-TTLRYGFLLLMKYPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRVKMPYMEAVIHEIQRFGDVIPMS-LA
RRVN-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-RFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFFTTIMQ-NFRFKS
PQLP---KDIDVSP-KHVGFA--------TIPP----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MALGG-A---FSI--FLALC-------------------LSC-
-LLILIAW--KRTS-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PIPFLGNL-------LQV-----RI-D-----
----------AIF--Q-SF----LK---LQKKYGP-VFTVHFGP----R-PVVVLYGHEA
V---KEALVDQADD-FSG--RGEMP---T-VEKS-FQGHG---------------LALS-
-NG--E-RWKVLRRFSLVVLRNF--GMGKRTIE--ERIQEEAGYLLEE------LH-KVK
----GA-P----I------------------------D-PTSYLSRT----VSNVICSIV
FGKRFNYEDK-CF-QNLMKMINETFVEMSK-----------PWA-----Q-L---Y----
-DMFWG-VM----QYFP-GS--HNHLYN-LIEDLKDFIAS---RVKINE----ASFDPSN
-PRDFID-----------CFLIKMYE---------DKSNPN-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGLLLMMKYPEVE----------------------------------
------------------------------------------------------------
-------AK-VH----E---E---------------------------------------
--------------IN---QVIGTH-RMPAVEDRAKMPYTDAVIHEIQRLTDIVPLG-VP
HNVT-RD--THFRGYFL--PK---------------------------------------
-----------------------GT-D-VYP--LIGSV-LRDP-KYFRYPDAFY-----P
QHFLDEQGRFK--KNDAFVAFSS-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLYFTSILQ-RFSLRS
LVPP---ADIDISH-RISGF-G-------NIPP----T---------YQLCFMAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLALL--------------------TGF
LLLLI--R--GQPK-AYSRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQM-----DR-G-----
----------GLL--K-SF----I--K-LRDKHGD-VFTVHLGP----R-PVVMLYGTET
I---KEALVDHSDA-FSG--RGAIA---V-IQPI-VQDY----------G-----VIFS-
-SG--E-RWKTLRRFSLATMRDF--GMGKRSVE--ERIKEEAQCLVEE------LK-KYE
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFDYTDH-QF-LHLLDLFYQTLSLISS-----------FSS-----QL----F----
-ELFSA-VL----KYFP-GT--HRQISK-NIQEILNYIGH---SVEQHK----ATLDPSA
-PRDFID-----------TYLLRMEK---------EKSNHH-TEFHHQNLL-ISVLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVISAH-HVPTLEDRIKMPYTEAVIHEIQRFSDLAPIG-LP
HTVT-KD--TVFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-QYFEQPDKFN-----P
EHFLDANGALK--KSEAFLPFST-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTALLQ-NFSLSS
PVAP---EDIDLTP-KESGFV--------KIPP----V---------YRICFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MGLGW-A---LTM--FLELF-------------------FSC-
-LLIFIAW--KRMN-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PIPFLGNL-------LQV-----QT-D-----
----------AVF--Q-SF----MK---LSEKYGP-VFTVYMGP----R-PVVVLCGHEA
V---KEALVDQADD-FSG--RGQLA---S-VERN-FQGEGRQKPETDILAG----VALS-
-NG--E-RWRSPRRFSLTILQNF--GMGKQSIE--E-----NSYLLEE------FQ-KTK
----GA-P----I------------------------D-PTFFLGRS----VSNVISSVV
FGSRFDYEDK-QF-LKLVQLPTC------------------LFP-----Q-L---Y----
-DMYSG-IM----QYLP-GR--HNRVYC-LIEELKDFVAS---RVKINE----ATFDHQN
-PQDFID-----------CFLVKMHQ---------DKNNPH-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
-------AK-IL----E---E---------------------------------------
--------------IN---QVIGPH-QLTSVDDRVKMPYTDAVIHEIQRLIDIVPVG-VP
HNVT-RD--TQFRGYLL--PK---------------------------------------
-----------------------GT-N-VLA--LLGSV-LKDP-KYFRYPDAFY-----P
QHFLDENRRFK--KNDAFVPFSS-GK----------------------------------
--------------------------RI-CL--GEAMAR--MELFLYFILILQ-NFSLRS
LVPP---ADIDITP-KLSGF-G-------NIPP----T---------YKLCLVARSAQPP
VGQGGSSE-----------------------ELSSPLL----------SSLLRLSNPGSI
P-----------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----A-N---

PF00067 // ENSGT00880000137861_0_Domain_2 (492, 1251)

-I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFYLKNLV-MTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDMLPMG-LA
HRVN-RD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-RFFSNPQDFN-----P
QHFLDKKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFFTTIMQ-NFRFKS
PQSP---KDIDVSP-KHAGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MALLV--ILGIC-------------------LSC-
-LFVFSLW--NQYH-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIVGNI-------LQV-----DI-K-----
----------NIS--K-SL----N---MLAKEYGP-VFTVYLGM----K-PTVVLHGYET
L---KEALVDRGDE-FSG--KTQSS---L-LSRV-KEGL----------G-----IIFS-
-NG--E-IWKQTRRFSLMVLRSM--GMGKKTIE--DRIQEEVLYLLDA------LR-KTN
----GA-P----C------------------------D-PSFLLACV----PCNVISAVI
FQHRFDYNDE-IF-QKVTESFHRIIKALES-----------PWA-----QL----C----
-SIYP--VL----YCLP-GS--HKSFLK-HEAEQHEFILK---EIKRHQ----ESLNPSN
-PQDFID-----------HFLIKME-K--------EKQNKK-SEFTMENLV-ATISDLFS
AGT-ETTS-STIKYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-IQ----E---E---------------------------------------
--------------IA---RVVGRH-RSPCMQDRNHMPYTDAVLHEIQRYIDLVPIP-LP
RKTT-QD--VVFRGYHI--PK---------------------------------------
-----------------------GT-S-VMT--CLNSV-LHDD-KEFPSPEKFD-----P
GHFLDERGNFK--KSDHFMAFSA-GR----------------------------------
--------------------------RA-CI--GEGLAR--MEMFLILTSILQ-HFTLKP
LVNP---EDIDTTP-AHTGL-L-------YLPP----P---------YELCFIPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDGAV--VLVLC-------------------LSC-
-LLLLSLW--KQSS-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPILGNI-------LQL-----DV-K-----
----------NIS--K-SL----S--NL-SKVYGP-VYTVYLGL----K-PTVVLHGYEA
M---KEALIDAGEE-FSG--RGHFP---M-AERV-NKGH-----------G----IIFS-
-NG--K-IWKETRRFSLMTLRNF--GMGKRSIE--ERIQEEACCLVEE------LR-KTN
----AS-P----C------------------------D-PTFLLGCA----PCNVICSII
FHNRFDYTDP-NF-LTLLEKFNENFKIMST-----------PWM-----QV----C----
-SNFPA-LI----DYLP-GS--HNKVLK-NSAYVKSYILE---KVKEHQ----ASLDVND
-PRDFID-----------CFLIKME-Q--------EKHNHQ-MAFTFENLI-ATISDLFE
AGT-ETTS-TTLRYGLLLMLKHPDVT----------------------------------
------------------------------------------------------------
-------AK-VQ----K---E---------------------------------------
--------------ID---SVIERH-RSPCMQDRIHMPYTDAVVHEIQRYIDLVPIG-LP
HTVT-RD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VLT--SLTSV-LNDD-QEFPNPEVFD-----P
GHFLDESGNFK--KSDCFMPFST-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTSILQ-KFTLEP
VVDL---KDINTTP-VYSGF-S-------HVPR----S---------YQLRFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEVGG-V---FTI--FLGLC-------------------LSC-
-LLILIAW--KRRN-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPFVGNL-------WQV-----RI-D-----
----------ATF--Q-SL----MK---LQKKYGS-VFTVYLGP----R-PVVVLCGHEA
V---KEALVDQADD-FSG--RGEMP---T-LERN-FQGHG---------------LALS-
-NG--E-RWKTLRRFSLTVLRNF--GMGKRSIE--ERIQEEAGYLLEE------LR-KTK
----GA-P----I------------------------E-PTFYLSRT----VSNVISSVV
FGSRFDYEDK-QF-LSLLRMINESFIEMSI-----------PYA-----Q-L---Y----
-DMYSG-VL----QYFP-GR--HNRLYY-LIEDLKEFTAS---RVKINK----ASFDPQN
-PRDFID-----------SFLIKMHQ---------DKSDPH-SEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGFLLLMKYPEVE----------------------------------
------------------------------------------------------------
-------AK-IY----E---E---------------------------------------
--------------IN---QVIGPH-RIPSVDDRVKMPYTDAVIHEIQRLTDIVPLG-VP
HNVI-RD--THFRGYFL--PK---------------------------------------
-----------------------GT-D-VYP--MIGSV-LKDP-KYFRYPDSFY-----P
EHFLDEQGRFK--KNEAFVVFSS-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLYFTSILQ-NFSLRS
LVPP---ADIDITP-RISGF-G-------NIPP----I---------YELCFVPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------SDTSTMLASGLL----LG--ALLFC-------------------LS--
TLVVLSVW--RQR-KVRSSL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NMEK-----
-----------MY--D-S-------LMKIGQKYGP-VFTVHLGH----R-TVVVLTGYEA
V---KEALVDQAEE-FSG--RGKQATLEW----L-FKG--------------FGV-AFG-
-NG--E-RARQLRRFSITTLRDF--GLGKRGIE--ERIQEEAGFLIEALRG-------TK
----GE-A----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFEYEDK-QF-LSLLRMMLGSFQFTAT-----------SMG--Q---L----Y----
-EMFSP-VM----KHLP-GP--QQQAFK-DLKGLEVFITE---KVWQNQ----ATLDPNS
-PRNFID-----------SFLIKMQE---------EKKNPN-TEFFMRNLT-MTTLNLFF
AGT-ETIS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---RVIGRN-RSPKFEDKAKMPYTEAVIHEIQRFGDLIPMG-LA
RRVI-KD--TKFRGYLL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDR-NFFACPEAFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRR-CF--GKGLAR--MELFLFLTTILQ-NFCFQS
PVPN---EAIDISP-KAVGFA--------TMPR----S---------YTISFLPW-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELGG-A---FTI--FLALC-------------------LSC-
-LFILIAW--KQRS-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PIPFLGNL-------LQV-----ST-D-----
----------ATF--Q-SF----MK---LKEKYGP-VFTVYMGP----R-PVVVLCGHEA
V---KEALVDKADD-FSG--RGELA---S-IERN-FQGYG---------------VALA-
-NG--E-RWRILRRFSLTILRDF--GMGKRSIE--ERIQEEAGFLLEE------LR-KTK
----GE-P----I------------------------D-PTFFLSRT----VSNVISSVV
FGSRFDYEDK-QF-LKLLQMINESFIEMST-----------PWA-----Q-L---Y----
-DMYSG-VM----QYLP-GR--HNRIYY-LIEELKDFIAS---KVKVNE----ASLDPQN
-PRDFID-----------CFIIKMHQ---------DKNNPN-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGMLLLLKYPEVE----------------------------------
------------------------------------------------------------
-------XX-XX----X---X---------------------------------------
--------------XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX---XXXXXXXXX-XX
XXXX-XX--XXXXXXXX--XX---------------------------------------
-----------------------XX-X-XXX--XXXSV-LKDP-KYFRYPDAFY-----P
QHFLDEQGRFR--KNEAFVPFSS-GK----------------------------------
--------------------------RI-CL--GEAMAR--MELFLYFTSILQ-NFSLRS
LVPP---KDIDITP-KVSGF-G-------NIPP----T---------YELCLMAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLVV--VLVLC-------------------LSC-
-LLLLSLW--KQSS-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPILGNI-------LQL-----DV-K-----
----------NIS--K-SL----S--NL-SKVYGP-VFTVYFGM----K-PLVVLHGYEA
V---KEALIDLGEE-FSG--RGLLP---V-SEKT-RKGH-----------G----IIFS-
-NG--K-IWKETRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GL-P----C------------------------D-PTFILGCA----PCNVICSII
FQNRFEYKDQ-VF-LAIMKMLTENARILSS-----------PWM-----QV----C----
-NTFPV-LI----DCFP-GS--HNKFFK-NFANIKSYIFE---KTREHQ----TSLDINN
-PQDFID-----------CFLIRME-Q--------EKHNQE-LVYTVENLA-NTILDLFI
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----G---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYTDAVIHEIQRYIDLIPTS-LP
HAVT-HD--IKFRNYLI--PK---------------------------------------
-----------------------GT-N-ILT--SLTSV-LHDG-KEFPNPEVFD-----P
GHFLDECGNFR--KSDYFMAFSA-GK----------------------------------
--------------------------RI-CL--GKGLAR--VELFLFLTTILQ-KFTLKS
VVDP---KDLDVTP-VVNGL-A-------SVPP----F---------YRLCFIPM-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------LAKRYGP-VFTLYLGS----R-RTVVLHGYKA
V---KEVLLTHKNE-FSG--RGEIPAIKE----YKDKG-----------------IIFN-
-NG--P-TWKDVRRFSLSVLRDY--GMGKQGNE--ARIQREAQFLLEE------LR-KTQ
----GQ-P----F------------------------D-PTFLIGGA----PFNVIADIL
FHRRFDYKDK-TC-LRLMHLFNEDFYLLST-----------PWL-----QL----Y----
-NNFSQ-YL----HYMP-GS--HRKVIK-NVSEIKAYTLE---RAKENL----QSLDIDC
-PRDVTD-----------CLLAEMEK---------EKRSGKPPVYTMENIS-VTLADLFF
AGT-ETTS-TTLRYGLLILMKYPEIE----------------------------------
------------------------------------------------------------
-------DT-IL----C---N---------------------------------------
--------------IK---FKQSSSLRSP---------------GKRLRFVNLTNG----
----------------N--TY---------------------------------------
-----------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (1044, 1182)

GT-V-IIP--TLDSL-LYDS-QEFPDPEQFK-----P
EHFLNENGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--M------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDSIST----AIL--LLLLA-------------------LVCL
LLT-L------S-SRDKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLSILGNL-------LLL-----CS-Q-----
----------DML--T-SL----T---KLSKEYGS-MYTVHLGP----R-RVVVLSGYQA
V---KEALVDQGEE-FSG--RGDYP---A-FFNF-TKGN----------G-----IAFS-
-SG--D-RWKVLRQFSIQILRNF--GMGKRSIE--ERILEEGSFLLAE------LR-KTE
----GE-P----F------------------------D-PTFVLSRS----VSNIICSVL
FGSRFDYDDE-RL-LTIIRLINDNFQIMSS-----------PWG-----EL----Y----
-DIFPS-LL----DWVP-GP--HQRIFQ-NFKCLRDLIAH---SVHDHQ----ASLDPRS
-PRDFIQ-----------CFLTKMA-E--------EKEDPL-SHFHMDTLL-MTTHNLLF
GGT-KTVS-TTLHHAFLALMKYPKVQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---LVVGRA-RLPALKDRAAMPYTDAVIHEVQRFADIIPMN-LP
HRVT-RD--TAFRGFLI--PK---------------------------------------
-----------------------GT-D-VIT--LLNTV-HYDP-SQFLTPQEFN-----P
EHFLDANQSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GESLAR--MELFLYLTAILQ-SFSLQP
LGAP---EDIDLTP-LSSGL-G-------NLPR----P---------FQLCLRPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDPSVL------L--LFALF--------------------TGF
LLLLI--R--GQGN-GYGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPC---PLPLLGNV-------LQM-----DR-R-----
----------GLL--K-SF----I--Q-LRDKYGD-VVTVHLGP----R-PIVMLYGTET
I---REALVDHAEA-FSG--RGTVA---V-VQPI-IQDY----------G-----MIFA-
-NG--E-RWKILRRFSLATMRDF--GMGKRSVE--ERIKEEAQCLVEE------LK-KYK
----GA-P----L------------------------D-PTFHLQCI----TANIICSIV
FGERFDYTDH-QF-LHLLDLFYEILSLVSS-----------FSS-----QV----F----
-ELFPG-FL----KYFP-GT--HRHISK-NIEEILNFIGH---CVEKHR----ATLDPST
-PRDFID-----------TYLLRMEK---------EKLNHH-TEFHHQNLM-MSVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVIGSH-RVPTLDDRIKMPYTDAVIHEIQRFSDLVPIG-LP
HRVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------NI-E-VYP--ILSSA-LHDP-QYFEHPDTFN-----P
EHFLDANGALK--KNEAFLPFST-------------------------------------
------------------------GKRV-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PVSP---KDIDLTP-KESGFA--------KIPP----T---------YQICFLSRQLG--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLVV--VLVLC-------------------LSS-
-LLLFSLW--KQSY-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQL-----DM-K-----
----------DIS--N-SM----S--NF-AKTYGP-VFTLYLGM----K-PTVVLHGYEA
I---KEALIDQGEE-FSG--RGHFA---V-AERT-NKEF-----------G----VVFS-
-NG--K-IWKETRRFSLMTLRNF--GMGKRSLE--NRVQEEARCLVEE------LR-KTK
----AL-P----C------------------------D-PTFILACA----PCNVICSII
FQNRFEYTDQ-HF-LNLIGILNENTEILST-----------PWM-----QM----C----
-NIFPM-LL----DYFP-GI--HNKLFN-NAIFLKSYILG---KVKEHQ----ESLDVNN
-PRDYID-----------CFLIKME-Q--------EKHNQQ-SEFITENLL-ATIADLFG
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCVQDRGSMPYTNAVIHEILRYIDLIPLS-LP
HAVT-RD--IKFRDYII--PKSG-------------------------------------
----------------------TGH-D-HMT--SLSSV-LYDK-KEFSNPEMFD-----P
GHFLDASGNFM--KSDYFMAFSA-GK----------------------------------
--------------------------RI-CL--GEGLAR--MEIFLFLTTILQ-KFTLKS
LVDP---KHIDTTP-VVNGF-A-------SLPP----L---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDSLV--VLVLC-------------------LSC-
-LLLLSLW--RQRS-GRGKF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNI-------LQI-----DI-K-----
----------DVS--K-SL----T--NL-SKVYGP-VFTLYFGL----E-RMVVLHGYEA
V---KEALIDLGEE-FSG--RGHFP---L-ADRA-NRGF-----------G----IVFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FHKRFDYKDQ-QF-LKVMEKLNENVKILSS-----------PWI-----QI----C----
-NNFPP-FI----DYFP-GA--HNKLLK-NVAFLKSYILE---KVKEHQ----ESMDMNN
-PRDFID-----------CFLMKME-K--------EKHNQQ-SEFTIENLE-NTAVDLFG
AGT-ETTS-TTLRYALLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRN-RSPCMQDRSHMPYTDAVVHEIQRYIDLLPTN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-ILI--SLTSV-LHDN-KEFPNPEMFD-----P
RHFLDEGGNFK--KSNYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLFLTSVLQ-NFNLKS
LVDP---KDLDTTP-VVNGF-A-------SVPP----F---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDGVST----AIL--FLILA-------------------VISL
ALT-F------N-SWGKGQL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPK---PLPILGNL-------LQF-----RS-Q-----
----------DLL--T-SL----T---KLTKKYGS-VYTVYLGP----R-RVVVLSGYQT
V---KEALVDKGEE-FSG--RGSYP---V-FFNF-TKGN----------G-----IAFS-
-NG--E-RWKALRRFSVQILRNF--GMGKRSIE--ERILEEGSFLIEV------LR-KTE
----GK-P----F------------------------D-PVFILSRS----VSNIICSVI
FGSRFDYDDE-RL-LTIIRFINDNFQIMSS-----------PWG-----EM----Y----
-NIFPS-LL----DWVP-GP--HRRMFR-NFRGMKELIAR---SVREHQ----ESLDPNS
-PRDFID-----------CFLTKMA-Q--------EKKDPL-SHFQMDTLL-MTTHNLLF
GGT-ETVG-TTMRHAFLILMKYPKVQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---RVVGRS-RMPLLEDRANMPYTDAVIHEVQRFADVIPMN-LP
HRVI-RD--TPFRGFLI--PK---------------------------------------
-----------------------GT-D-VIT--LLNTV-HYDS-DQFKTPHEFN-----P
EHFLDANQCFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GEPLAR--MELFLYFTSILQ-NFTLHP
LVEP---EDIDLTP-LSSGL-G-------NLPR----P---------FQLCVRAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----E-P----F-----------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (517, 1251)

-D-PTFVLSRS----VSNIICSVL
FGSCFHYDDE-RL-LTIIRLINDNFQIMSS-----------PWG-----EL----Y----
-NIFPS-LL----DWVP-GP--HQRIFQ-NFKCLRDLIAH---SVHDHQ----ASLDPRS
-PRDFID-----------CFLTKMAE-----------EDP-LSHFHMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFLALMKYPKVQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---LAVGRA-RLPG----------HPVIHQVQRFADIIPMN-LP
HRVT-RD--TAFRGFLI--PKGT-------------------------------------
--------------------------D-IIT--LLNTV-HYDP-SQFLTPQEFN-----H
EHFWMP----------------I-------------------------------------
------------------------RRRL-CL--GESLAR--TELFLYLTAILQS-FSLQP
LGAP---EDIDLTR-LSSGPG--------NLPR----P---------FQLCLLLC-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPIL--VLVFT-------------------LSC-
-LLLLSGW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPIIGNI-------LQI-----DI-K-----
----------NIS--K-SF----N--YF-SKVYGP-VFTLYFGS----K-PTVVVHGYEA
V---KEALDDLGEE-FSG--RGSFQ---I-FERI-NSDL----------G-----VIFS-
-NG--T-KWKELRRFSIMTLRSF--GMGKRSIE--DRIQEEASCLVKE------LR-KTK
----GS-L----C------------------------D-PTFILSCA----PSNVICSVI
FHNRFDYKDE-KF-LNLMERLNENFKILNS-----------PWM-----QV----Y----
-NALPT-LI----SYLP-GS--HNKIIK-NFTEIKSYILG---RVKEHQ----ETLDMDN
-PRDLID-----------CFLIKME-Q--------EKHNSH-SEFTIESLM-ATVTDIFV
AGT-ETTN-ITLRYGLLLLLKYTEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----A---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRTRMPYTDAMVHEIQRYIDLIPNN-VP
HAAT-CN--VRFRNYVI--PK---------------------------------------
-----------------------GT-D-LVT--SLTSV-LHDD-KEFPNPEVFD-----P
GHFLDENGNFK--KSDYFMPFSI-GK----------------------------------
--------------------------RM-CV--GEALAR--TELFLILTTILQ-NFNLKS
LVDT---KDIDTTP-VANTF-G-------RVPP----S---------YQLYFVPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVLGV--FLGLL-------------------LTC-
-LLLLSLW--KQNS-QRRNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQL-----DL-K-----
----------DIS--K-SL----R--NF-SKVYGP-VFTLYLGR----N-PAVVLHGYEA
V---KEALTDHGEE-FAG--RGVFP---V-FDKF-KKNC-----------G----VVFS-
-SG--R-TWKEMRRFSLMTLRNF--GMGRRSIE--DRIQEEARCLVDE------LR-KTN
----GE-P----C------------------------D-PTFILGCA----PCNVICSIV
FQNRFDYKDQ-EF-LTFLDILNENVEILSS-----------PWI-----QI----C----
-NNFPA-VI----DYLP-GR--HRKLHK-NFAFAEHYFLS---KVKQHQ----ESLDINS
-PRDFID-----------CFLIKME-Q--------EKHNPK-TEFTCDNLV-FTASDLFA
AGT-ETTS-TTLRYSLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---CVIGRH-RSPCMQDRHSMPYTDAVLHEIQRYIDLLPTS-LP
HAVT-RD--VKFREYLI--PK---------------------------------------
-----------------------GT-T-VIA--SLSSV-LYDD-KEFPNPERFD-----P
SHFLDERGKFK--KSDYFFPFST-GK----------------------------------
--------------------------RI-CV--GEGLAR--AELFLFLTTILQ-NFNLKS
PVDL---KDLDTTP-VANGF-A-------SVPP----K---------FQICFIPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVL------L--FLVLL--------------------TGL
LLLLV--Q--RHPN-AHGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--R-SF----L--R-FREKYGD-VFTVYLGP----R-PVVMLCGVEA
I---REALVDNAEA-FSG--RGKIA---I-TDPV-FQGY----------G-----VVFA-
-NG--N-RWKVLRRFSLTTMRDF--GMGKRSVE--ERIQEEAQCLIEE------LR-KSK
----GA-L----V------------------------D-PTFLFHSI----TANIICSIV
FGKRFHYQDQ-EF-LKILNLFYHTFSLASS-----------MFG-----QL----F----
-ELLSG-FL----KYFP-GA--HRQVYK-NLQEINAYIGH---SVEKHR----ETLDPSA
-PQDLID-----------SYLLQMEK---------EKSNPH-SEFSHRNLI-INTLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHIA-ERIYKEIE---QVIGPH-RPPALDDRAKMPYTEAVIHEIQRFADLLPMG-VP
HIVT-QQ--TSFRGYII--PK---------------------------------------
-----------------------DT-E-VFP--LLSTA-LHDP-HYFEKPDTFN-----P
DHFLDANGALK--KNEAFIPFSL-------------------------------------
------------------------GRRI-CL--GEGIAR--NELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-QESGVG--------KIPP----T---------YQIRFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSIL------L--FLALL--------------------TGL
LLLLV--Q--RHPN-AHGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--R-SF----L--R-FREKYGD-VFTVYLGP----R-PVVMLCGVEA
I---REALVDNAEA-FSG--RGKIA---I-TDPV-FQGY----------G-----VVFA-
-NG--N-RWKVLRRFSLTTMRDF--GMGKRSVE--ERIQEEAQCLIEE------LR-KSK
----GA-L----V------------------------D-PTFLFHSI----TANIICSIV
FGKRFHYQDQ-EF-LKILNLFYHTFSLASS-----------MFG-----QL----F----
-ELLSG-FL----KYFP-GA--HRQVYK-NLQEINAYIGH---SVEKHR----ETLDPSA
-PQDLID-----------SYLLQMEK---------EKSNPH-SEFSHRNLI-INTLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-ERIYKEIE---QVIGPH-RPPALDDRAKMPYTEAVIHEIQRFADLLPMG-VP
HIVT-QQ--TSFRGYII--PK---------------------------------------
-----------------------DM-E-VFP--LLSTA-LHDP-HYFEKPDTFN-----P
DHFLDANGALK--KNEAFIPFSL-------------------------------------
------------------------GRRI-CL--GEGIAR--NELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-QESGVG--------KIPP----K---------YQIRFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MALFI--FLGIW-------------------LSC-
-FLFLFLW--NQHR-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIVGNI-------LQV-----DV-K-----
----------NIS--K-SM----G---MLAKKYGP-VFTVYLGM----K-PTVVLHGYKA
M---KEALIDQGDE-FSD--KTDSS---L-LSRT-SQGL----------G-----IVFS-
-NG--E-TWKQTRRFSLMVLRSM--GMGKKTIE--DRIQEEILYMLDA------LR-KTN
----GS-P----C------------------------D-PSFLLACV----PCNVISTVI
FQHRFDYNDQ-TF-QDFMENFHRKIEILAS-----------PWS-----QL----C----
-SAYP--IL----YYLP-GI--HNRFLK-DVTQQKKFILE---EINRHQ----KSLDLSN
-PQDFID-----------YFLIKME-K--------EKHNQK-SEFTMDNLV-VSIGDLFG
AGT-ETTS-STVKYGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-IQ----E---E---------------------------------------
--------------IA---HVIGRH-RRPTMQDRNHMPYTDAVLHEIQRYIDFVPIP-SP
RKTT-QD--VEFRGYHI--PK---------------------------------------
-----------------------GT-S-VMA--CLTSV-LNDD-KEFPNPEKFD-----P
GHFLDEKGNFK--KSDYFVAFSA-GR----------------------------------
--------------------------RA-CI--GEGLAR--MEMFLILTNILQ-HFTLKP
LVKP---EDIDTKP-VQTGL-L-------HVPP----P---------FELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M

PF00067 // ENSGT00880000137861_0_Domain_2 (355, 1252)

LCGTET
I---REALVDQAEA-FSG--RGTIA---V-TEAV-FKGY----------G-----VIMA-
-NG--E-RWKALRRFSVATMRDF--GMGKRSVE--ERIQDEAQWLVEE------LR-KSQ
----GG-L----V------------------------D-TLFLFQSV----TANIICSIV
FGKRFDYKDR-QF-LRLLDLIYRTFSLFSC-----------FSS-----QV----F----
-ELYSS-IL----KHFP-GT--HREVYK-NLQEINTFIGH---SVEEHR----ETLDPST
-PRDFID-----------SYLLRMEK---------DKSDPH-TEFHHKNLI-LTSLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLFL
LKYPHVT-ERVHKEID---QVIGSH-RRPALDDRTKMPYTEAVICEIQRFADLAPIG-AP
HKVT-KD--THFRGFII--PK---------------------------------------
-----------------------NT-E-IYP--ILTTA-LNDP-RHFETPDTFN-----P
DHFLDAKGVLK--KSEALIPFSL-------------------------------------
------------------------GKRI-CL--GEGIAR--AELFLFLTTILQ-NFSISS
PVAP---EDIDLTP-QEVGLG--------RIAP----T---------YQICFLPRSGE--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGML----LV--ALLAC-------------------LT--
AMVLMSVW--RQR-KFWGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 746)

PPGPT---PLPFIGNY-------LQL-----DTEQ-----
-----------MY--S-S-------LMKXXERYGS-VFTVHLGP----R-WVVVLCGYDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIEAFRG-------TH
----SA-I----I------------------------D-PTFYLSRT----VSNVISSIV
FGNRFDYDDK-EF-LSLMRMMLGSFQFTAT-----------STG-----QL----Y----
-DMFSS-VM----KHLP-GP--QQQAFK-ELQGLRDFIAK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------ENKNPN-TEFHMKNLV-LTSLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPWGLT-T---T--VLLTC-------------------VLF-
-LIFLSLW--NHGTKK-GKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIFGNL-------LQF-----DF-K-----
----------NMA--S-TF----S---ELAKKYGS-IYTLYFGT----Q-RVVVLYGYNI
V---KEALIDKGDI-FME--RGNVP---I-FEDT-VKG----------QG-----VVFS-
-RG--E-RWKQIRRFSLMTLRNF--GMGKRTIE--ERVQEEAQCLVEE------LR-KTK
----GQ-P----N------------------------D-PTFILGCA----PCNVICSIL
FRDRFNYKDE-KF-LYLMGLLNENFQLFTK-----------PWI-----QL----Y----
-NFLPA-FR----VHLP-GK--HKQLFK-NVEELKCFILE---RVKEHQ----EILDPNN
-PQDYID-----------CYLSKMQ-Q--------EKNNPQ-SEFDVENLL-MTGADLFS
AGT-ETTS-STLRYGLLLILKHPEVQ----------------------------------
------------------------------------------------------------
-------AK-IH----E---E---------------------------------------
--------------IN---RVIGHN-RIPSIKDRQDMPYMDAVVHEVQRFIDLIPLN-LP
HAVN-QD--IQLQQYTI--PK---------------------------------------
-----------------------GT-N-ILP--LLSPV-LCDS-KEFSNPDKFD-----P
QHFLDKNGSFK--KSDCFMPFSA-GK----------------------------------
--------------------------RA-CL--GEGLAR--MELFLFLTTILQ-NFTLKP
VGDP---NEISMKN-NHVGF-T-------SVPP----Y---------YQLCFLPHKA---
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPWGLT-T---T--VLLTC-------------------VLF-
-LIFLSLW--NHGTKK-GKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIFGNL-------LQF-----DF-K-----
----------NMA--S-TF----S---ELAKKYGS-IYTLYFGM----Q-RVVVLHGYNI
V---KEALIDKGDI-FME--RGNVP---I-FEDT-VKG----------QG-----VVFS-
-RG--E-KWKQIRRFSLMTLRNF--GMGKRTIE--ERVQEEAQCLVEE------LR-KTK
----GQ-P----N------------------------D-PTFILGCA----PCNVICSIL
FRERFNYKDE-KF-LYLMGLLNENFQLFNK-----------PWI-----QL----Y----
-NFLPA-FR----VHLP-GK--HKQLFK-NVEELKCFILE---RVKEHQ----EILDPNN
-PQDYID-----------CYLSKMQ-Q--------EKNNPQ-SEFDVENLI-MTALDLFA
AGT-GTTS-STLRYGLLLILKHPEVQ----------------------------------
------------------------------------------------------------
-------AK-IH----E---E---------------------------------------
--------------IN---RVIGHN-RIPSIKDRQDMPYMDAVVHEVQRFIDLLPLN-LP
HAVN-QD--IQLQQYTI--PK---------------------------------------
-----------------------GT-N-IFP--LLSPV-LRDS-KEFSNPDKFD-----P
QHFLDKNGSFK--KSDYFMPFSA-GK----------------------------------
--------------------------RA-CL--GEGLAR--MELFLFLTTILQ-NFTLKP
VGDP---NEISVKN-NHVGF-T-------NVPP----Y---------YQLCFLPHKA---
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVLGV--FLGLV-------------------LSC-
-LLLLSLW--RQSS-QRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNI-------LQI-----DL-K-----
----------NIS--K-SL----R--DF-SKVYGP-MFTLYLGR----K-PAVVLHGYEV
V---KEALIDHGEE-FAG--RGTFP---V-FDKI-AKGR-----------G----IVFS-
-DG--R-IWKEMRRFSLVTLRNF--GMGKRSIE--DRVQEEARCLVEE------LK-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSIV
FQNRFDYKDQ-EF-LTFMNILNENVEILSS-----------PWI-----QI----C----
-NNFPA-LI----DYLP-GS--HRKLLK-NFTFSKHYFLA---KLIEHQ----KSLDINN
-PRDFID-----------CFLIKME-Q--------EKHNPK-TAFTSENLV-FSAGDLFA
AGT-ETTS-TTLRYSLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----A---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSHMPYTDAVLHEIQRYIDLLPTS-LP
HSVT-CD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIA--SLTSM-LHDN-KEFPNPEKFD-----P
GHFLDENGKFK--KSDYFFPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
PVDP---KDLDTTA-VANGF-V-------SVPP----E---------FQICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDSIST----AIL--LLLLA-------------------LVCL
LLT-L------S-SRDKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPILGNL-------LLL-----RS-Q-----
----------DML--T-SL----T---KLSKEYGS-MYTVHLGP----R-RVVVLSGYQA
V---KEALVDQGEE-FSG--RGDYP---A-FFNF-TKGN----------G-----IAFS-
-NG--D-RWKILRRFSIQILRNF--GMGKRSIE--ERILEEGSFLLAE------LR-KTE
----GE-P----F------------------------D-PTFVLSRS----VSNIICSVL
FGSRFDYDDE-RL-LTIIRLINDNFQIMSS-----------PWG-----EL----Y----
-NIFPS-LL----NWVP-GP--HQRIFQ-NFKCLRDLIAH---SVHDHQ----ASLDPRS
-PRDFID-----------CFLTKMA-E--------KKEDPL-SHFHMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFLALMKYPKVQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---LVVGRA-RLPALKDRAAMPYTDAVIHEVQRFADIIPMN-LP
HRVT-RD--TAFRGFLI--PK---------------------------------------
-----------------------GT-D-VIT--LLNTV-HYDP-SQFLTPQEFN-----P
EHFLDANQSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GESLAR--MELFLYLTAILQ-SFSLQP
LGAP---EDIDLTP-LSSGL-G-------NLPG----P---------FQLCLRPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----VV--ALLAC-------------------LS--
VMILMSIW--RQR-KLWGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISERYGP-VFTIHLGP----R-RVVVLCGQDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIQAFRD-------TR
----GA-F----I------------------------D-PTFYLSRT----VSNVISSIV
FGDRFEYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFITK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------ENKNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDMIPMG-LA
RRVI-KD--TKFRDFLL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPRDFY-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTILQ-NFRFKS
PQAP---WDIDVSP-KHVGFA--------TIPP----N---------YTMSFQLR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAVLGIT-----V--ALLGW-------------------MAI-
-LLFISVW--KQIH-SSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNL-------LQL-----DF-K-----
----------DIP--K-SF----G---RLAERFGP-VFTLYLGS----R-RVVVLHGYKA
V---REMLLNHKNE-FSG--RGEIPALRE----FKDKG-----------------IIFN-
-NG--P-TWKDTRRFSLTTLRDY--GMGKQGNE--DRIQQEAHFLLEE------LR-KTQ
----GQ-P----F------------------------D-PTFVIGCT----PFNVIAKIL
FNDRFDYKDK-QA-LRLMSLFNENFYLLST-----------PWL-----QV----Y----
-NNFSN-YL----QYMP-GS--HRKVIK-NTCEIKEYTLA---RVKEHQ----KSLDPSC
-PRDFID-----------CLLIEMEK---------DKHGTE-PLYTLENIA-VTVADLFF
AGT-ETTS-TTLRYGLLILLKHPEIE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---R--------------VQMPYMDAVVHEIQRFIDLVPSN-LP
HEAT-RD--TTFQGYVI--PK---------------------------------------
-----------------------GT-V-VIP--TLDSL-LYDK-QEFPDPEKFK-----P
EHFLNEEGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLLLSAILQ-HFNLKP
LVDP---EDIDLRS-IAVGF-G-------RIPP----R---------YKLCVVPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (329, 1103)

LREKYGS-VFTVYMGP----R-PVVVLCGHEA
V---KEALVDKADD-FSG--RGKVT---L-LERN-FQG----------YG-----VALA-
-NG--E-RWRILRRFSLTILRDF--GMGKRSIE--ERIQEEAGFLLEE------LR-KTK
----GN-P----I------------------------K-PTFFLSRT----VSNVISSVV
FGSRFDYEDK-QF-LKLIQILKEIPMEMNT-----------LWA-----QL----Y----
-DMYSG-VM----QYLP-GR--HNRAYY-LMEDLKDFIAQ---KIKTNE----ASLDPQN
-PRDFID-----------CFLIKMH-Q--------XXXXXX-XXXXXXXXX-XXXXXXXX
XXX-XXXX-XXXXXXXXXXXXXXXXX----------------------------------
------------------------------------------------------------
-------XK-IH----E---E---------------------------------------
--------------ID---QVIGTH-RIPSVNDRVKMPHTNAMIHEIQRVIDLLPMG-IP
HNVI-RD--TEFRGYLL--PK---------------------------------------
-----------------------GT-D-VFP--LLGSV-LKDP-KYFRYPDTFY-----P
EHFLDAKGHFK--NNEAFVPFST-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------TQS-ASMDLFT--VLAIC-------------------LSC-
-LILLFLW--NRSY-AQGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVVGNI-------LQI-----NM-K-----
----------NFN--E-SL----R--KL-AEVYGP-VFTVYVGT----Q-PTVVLHGYAA
V---KEALIDRGEE-FAG--RGSFP---V-IDYL-SRGL-----------G----VVFS-
-NG--E-IWKHTRRFSLTVLRNM--GMGKKTIE--DRIQEEALCLVEA------LK-KTN
----AS-P----C------------------------N-PSLLLGCA----PCNVICSVI
FQSRFEYSDE-KF-LTLLHYFNENLRIIST-----------TWI-----QL----Y----
-NAFPY-LM----HYLP-GS--HNEFFN-NFTEQKKFILE---QIKEHQ----ESLDLNN
-PRDFID-----------YFLIKME-K--------EKHNKQ-SVFTMDNLI-ITIWDMFS
AGT-ETTA-TTLKYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVVGRE-RGPCMQDKSHMPYTDAVIHEIQRYIDLVPNN-LP
HLVN-QD--IKFRGYFI--PK---------------------------------------
-----------------------GT-A-IVT--SLTSL-LHDD-KEFPNPDQFD-----P
GHFLDESGNFK--KSNYFMPFS-AGK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLLLTHILQ-HFTLKP
LVDP---KDIDTTP-VVNGF-G-------SVPP----S---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--AVIVC-------------------LS--
VMVLMSTW--QQR-KIFRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPFIGNY-------LQL-----DTEQ-----
-----------IY--N-S-------IMKISERYGP-VFTIYLGT----R-RVVVLCGYDA
V---KEALLDQAED-FSG--RGEQATFGW----I-FEN--------------HGV-VFS-
-NG--E-RCKHLRRFSISTLRDF--GLGKRGIE--ERIQEEAGFIVEALRS-------TG
----GT-F----I------------------------D-PTFYISQA----IANVICSIV
FGDRFDYEDK-EF-LSLLSMMLQSFQFTAT-----------STG--Q---L----L----
-EFFMS-VM----KHLP-GP--HQDAFK-NLTGLKNFIIK---KVEQNR----CTLDPNS
-PRNFID-----------SFLIRMKE---------EKNNPN-SEFFMKNLV-MTTLNLFI
AGT-ETVS-TTLRYALLLLMKYPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGRN-RQPKFEDRVKMPYTDAVIHEIQRFGDVIPMG-LA
RRVT-KD--TKFRDFLI--PKGT-------------------------------------
--------------------------E-VFP--ILGSV-LRDT-KFFSNPGDFN-----P
QHFLDEKGQFR--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTIMQ-NFRFKS
SQEP---QDIDVSP-KFVGFS--------TIPR----N---------YTMCFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--AFLAC-------------------LT--
VMVLMSVL--QQR-KSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--T-S-------LMKISERYGP-VFTIHLGP----R-RVVVLCGHDA
V---REALVDHAEE-FSG--RGKQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLIEALRG-------TR
----GA-N----I------------------------D-PTFFLSRT----VSNVISSIV
FGYRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------SAG--Q---L----Y----
-EMFSS-LM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNR----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFHLKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRVKMPYMEAVIHEIQRFGDVIPMG-LA
HRVN-KD--TKFRNFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-RFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GESLAR--MELFLFLTTIMQ-NFRFKS
PQSP---KDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------G----

PF00067 // ENSGT00880000137861_0_Domain_2 (415, 1252)

-IAFS-
-NG--D-RWKVLRKYSVQILRNF--GMGKRTIE--ERILEEGHFLLEE------LR-KTQ
----GK-P----F------------------------D-PTFVVSRS----VSNIICSVI
FGSRFDYDDD----LSIIHLINENFQIMSS-----------PWG-----EM----Y----
-NIFPN-LL----DWVP-GP--HRRLFK-NYGRIKDIIAR---SVREHQ----ASLDPNS
-PRDFID-----------CFLTKMA-Q--------EKQDPL-SHFFMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFRLLMKYPEVQ----------------------------------
------------------------------------------------------------
-------VR-VQ----E---E---------------------------------------
--------------ID---RVVGHE-RLPTVEDRAAMPYTDAVIHEVQRFADVIPMS-LP
HRVT-RD--TNFRGFTI--PR---------------------------------------
-----------------------GT-D-VIT--LLNTV-HYDP-SQFLKPKEFN-----P
EHFLDANMSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GEALAR--MELFLYLTAILQ-SFSLQP
LGAP---EDIDLTP-LSSGL-G-------NLPR----P---------YQLCVLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFI--ILATC-------------------LSC-
-LTLLFLW--NGSN-AKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPI---PLPIVGNI-------RQL-----NS-K-----
----------NIS--K-SI----S--ML-AKDYGP-VFTVYFGM----K-PTVVLHEYKA
I---KEALIDHGEE-FSG--RGSFP---V-MDRI-TQGL-----------G----VIFS-
-NG--E-RWKQTRRFSLMVLRNM--GMGKKTIE--DRIQEEALCLVAA------LK-KTN
----AS-P----S------------------------D-PTFLLGCV----PCNVISAII
FQNRFDYSDP-KF-QTLINYFNENFESVSA-----------PWI-----QL----Y----
-NAFPF--L----RFLP-GS--HNVIFK-NYALQINFILE---KVKEHQ----ESLDISN
-PRDFID-----------YFLIKME-K--------EKHNKQ-SEFTMDNLV-ATIWDMFN
AGT-ESTS-TTMRYGLLLLLKHPEIS----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---QVVGKN-RSPCMQDRSCMPYTDAVVHEIQRYIDLVPTS-LP
HEVT-QD--THFREYFI--PK---------------------------------------
-----------------------GT-T-ILA--DLTSV-LYDD-KEFPSPEKFD-----P
GHFLDENGNFK--KSDYFMPFS-TGK----------------------------------
--------------------------RA-CA--GEGLAR--MELFLNLTTILQ-NFTLKP
LVDP---KDIDTTP-VHKGL-G-------SVPP----F---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDGVTT----AIF--LLLLA-------------------IICL
SLT-F------T-ASDKGQL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPK---PLPILGNL-------LQL-----RS-Q-----
----------DLL--T-SL----T---KLSKEYGS-VYTVYLGP----R-RVVVLSGYQT
V---KEALVDKGEE-FSG--RGSYP---V-FFNF-TKGN----------G-----LAFS-
-NG--D-RWKVLRRWSIQILRNF--GMGKKSIE--NQILEESSFLLEV------LR-NTE
----GK-P----F------------------------D-PVFTLSRS----VSNIICSVI
FGRRFDYEDD-RL-LTIITFINDNFKIMSS-----------PWG-----EM----Y----
-NIFPN-LL----DWVP-GP--HRRLFQ-NYAGMKDLIAR---SIREHQ----DSLDPNS
-PRDFID-----------CFLIKMA-Q--------EKQDPL-SHFQMDTLL-MTTHNLLF
GGT-ETVG-TTLRHTFLILMKYPKIQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---RVVGRS-RSPTLEDRVSMPYTDAVIHEAQRFADIVPMN-LP
HRVI-RD--TPFRGFLI--PK---------------------------------------
-----------------------DT-D-VIT--LLNTV-HYDP-SQFKTPKEFN-----P
EHFLDANQSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GEPLAR--MELFLFLSSILQ-NFTLEP
TVKP---EDIDLTP-ISSGL-G-------KVPR----P---------FQLSIRAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAALGIV-----V--ALLVW-------------------MAT-
-LLLISIW--KHIY-SSWQL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIVGNI-------FQL-----EF-K-----
----------DIP--K-SF----T---RLAERFGP-VFTLYLGS----R-RFVVLHGYKA
V---KEVLLDYRNE-FSG--RGEIPAFRV----HQDKG-----------------IIFN-
-NG--P-TWQDTRRFSLTTLRDF--GMGKQGNE--QRIQREAQLLLGA------LW-KTH
----GQ-P----F------------------------D-PTFVIGFA----PYNVISDIL
FHRRADYNDR-TA-LRMLSLFNENFYLLST-----------PWI-----QL----Y----
-NNFSG-CI----RYLP-GS--HRKLMK-NVSEIKEYALE---GVKDHQ----RSLEASC
-PRDFTD-----------TMLLEMEK---------EKHSTD-PVYTLDNIA-VTVADLLF
AGT-ETTS-TTLRYGLLILMKYPEVE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RIPAIKDRLDMPYLDAVVHEIQRFIDLIPSN-LF
HEAT-RD--TVFRGYVI--PK---------------------------------------
-----------------------GT-V-IIP--TLDSL-LYDS-QEFPEPEKFK-----P
EHFLNENGKFK--YSDHFKPFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLFLASILQ-HFNLKS
PVDP---MDIDLSP-IAVGF-A-------KVPP----H---------YRLCVIPRSQ---
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGP----LLV--ALLVC-------------------LTVM
VLMS--VW--QQR-KSRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1167)

PLGPT---PLPFIGNY-------LQL-----NT-E-----
----------QMC--T-SL----M---KISERYGP-VFTLHLGP----R-RVVVLCGHDA
V---REALVDQAEE-FSG--RGEQA---T-FNWV-FKSY----------G-----VTFS-
-TL--E-RAKPLRHFSIATLRNF--G-------------EKAGFLIQA------FL-GTR
-----G-E----I------------------------N-PTFFLSRT----VSNVISS--
-----------TF-LSLLRMMRESFQFTAT-----------STG-----QL----H----
-EMFSS-VM----KHLP-GP--QQQTFK-ELQGLDDFIAK--------------------
---KFID-----------SFLIRLQE----------EKNP-NTEFYMKNLV-MTALNLFI
AGA-KTVS-TTLRYGFLLLTKHPEVE----------------------------------
------------------------------------------------------------
-------GK-VH----E---E---------------------------------------
--------------ID---RVISKN-RQPKFEDQARMPYTEAVIHEIQRFGDMLPMA-VA
HRVN-KD--TKFQDVFL--LKKC-------------------------------------
--------------------------S-LCW--AL-----------------FF-----S
NPQYFNPQQFK--KSDAFVPFSI-------------------------------------
------------------------GKRP-LF--AARPLL--TPAGASLTQLSFLWCSWYF
PGFQ---VPVRIYP-SVIS-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFV--VLVIC-------------------LSI-
-LIFLFLW--NQRH-AKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1249)

PPGPT---PLPIVGNI-------LQI-----NV-K-----
----------DFS--K-SI----S--KL-AEDYGP-VFTLYFGM----K-PTVVLHGYEA
V---KQVLIDQSEE-FSG--RGSLP---V-VDNI-NKGL-----------G----IAFS-
-NG--E-QWKQTRRFSLMVLRNM--GMGKRTIE--HRIQEEALCLVEA------LK-KTN
----GS-P----C------------------------D-PTLLLSYA----PCNVICSII
FQNRFEYSDE-NF-LTLAKYIHENAKIVST-----------PWI-----EL----Y----
-NAFPS-LL----HYLP-GS--HNTLFK-NMTEQRKFILE---KIKEHQ----ESLDLNN
-PQDFID-----------YFLIKME-K--------EKHNKQ-SEFTMDNLI-TSLWDLLT
AGI-ETTS-VTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------DD-GQDEIF----E---------------------------------------
--------------IN---RVVGRN-RSPCMQDRSRMPYTDAVIHEIQRYIDLVPNN-LP
HAAA-QD--IEFREYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDG-KEFPNPEQFD-----P
GHFLDKSGNFK--KSDYFMAFS-AGK----------------------------------
--------------------------RV-CA--GEGLAR--MELFLLLVSILQ-HFTLKP
LVDP---KNIDTTP-LLKAL-G-------SLPH----F---------YEVCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAM--ALVFC-------------------LSC-
-LLLLSLW--SQRS-GRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PSGPT---PLPIIGNI-------LQL-----DV-K-----
----------DIS--K-SL----T--NF-SKVYGP-VFTVYFGL----K-PIVVLHGYEA
V---KEALIDHGEE-FSG--RGSFP---V-AEKV-NKGL-----------G----ILFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSVV
FQKRFDYKDQ-RF-LNLMEKFNENLRLLSS-----------PWI-----QV----C----
-NNFPA-LI----DYLP-GS--HNKVLK-NFAYVKSYVLE---RIKEHQ----ESLDVNN
-PRDFID-----------CFLIKME-Q--------EKHNQQ-SEFTTENLI-ATVTDMFG
AGT-ETTS-TTLRFGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---HVVGRN-RSPCMQDRSHMPYTDAVVHEIQRYIDLIPTN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-IIT--SLNSV-LHND-KEFPNPEMFD-----P
GHFLDKSGNFK--KSDYFIPFST-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
QVDP---KDIDITP-IANSF-G-------RVPP----L---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MALFI--FLGIW-------------------LSC-
-FLFLFLW--NQHR-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIVGNI-------LQV-----DV-K-----
----------NIS--K-SM----G---MLAKKYGP-VFTVYLGM----K-PTVVLHGYKA
M---KEALIDQGDE-FSD--KTDSS---L-LSRT-SQGL----------G-----IVFS-
-NG--E-TWKQTRRFSLMVLRSM--GMGKKTIE--DRIQEEILYMLDA------LR-KTN
----GS-P----C------------------------D-PSFLLACV----PCNVISTVI
FQHRFDYNDQ-TF-QDFMENFHRKIEILAS-----------PWS-----QL----C----
-SAYP--IL----YYLP-GI--HNRFLK-DVTQQKKFILE---EINRHQ----KSLDLSN
-PQDFID-----------YFLIKME-K--------EKHNKK-SEFTMDNLV-VSIGDLFG
AGT-ETTS-STVKYGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-IQ----E---E---------------------------------------
--------------IA---HVIGRH-RRPTMQDRNHMPYTDAVLHEIQRYIDFVPIP-SP
RKTT-QD--VEFRGYHI--PK---------------------------------------
-----------------------GT-S-VMA--CLTSV-LNDD-KEFPNPEKFD-----P
GHFLDEKGNFK--KSDYFVAFSA-GR----------------------------------
--------------------------RA-CI--GEGLAR--MEMFLILTNILQ-HFTLKP
LVKP---EDIDTKP-VQTGL-L-------HVPP----P---------FELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFI--ILAIC-------------------LSC-
-LILLFLW--NGSN-AKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------QQL-----NS-K-----
----------NIS--K-SI----S--ML-AKDYGP-VFTVYFGM----K-PTVVLHGYKA
I---KEALIDHGEE-FSG--RGSLP---V-VDRI-TQGL-----------G----VVFS-
-NG--E-RWKQIRRFSLMVLRNM--GMGKKTIE--DRIQEEALCLVAA------LK-KTN
----AS-P----C------------------------D-PTFLLGCV----PCNVISTII
FQNRFDYSDP-KF-QTLIKYFNENFENVST-----------PWI-----QL----Y----
-NAFPF--L----RVLP-GG--HNVIFK-NHALQVNFILE---KVKEHQ----ESLDISN
-PRDFID-----------YFLIKME-K--------EKHNKQ-SEFTMDNLV-ATIWDMFS
AGT-ETTS-TTMRYGLLLLLKHPEIS----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---QVVGKN-RSPCMQDRSRMPYTDAVVHEIQRYTDLVPTS-LP
HAVT-QD--THFREYFI--PK---------------------------------------
-----------------------GT-T-ILT--DLSSV-LNDD-KEFPNPEKFD-----P
GHFLDESGNFK--KSDYFMVFS-AGK----------------------------------
--------------------------RA-CA--GEGLAR--MELFLILTTILQ-NFTLKP
LVDP---KDIDTTP-VHKGL-G-------SVPP----S---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSTL------L--LLTLL--------------------LGF
LVLLV--R--RHPK-ARGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQM-----DK-G-----
----------GLL--N-SF----R--Q-FQGKYGD-VFTLHLGP----K-PVVMLYGTEA
I---REALVDQAEA-FSG--RTAIA---V-LKPI-FMDY----------G-----VIFS-
-NG--E-RWKILRRFSLVTMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFDYRDG-QF-LRLLDLFYQITSLLST-----------LSS-----QM----F----
-EFFSG-FL----KYFP-GT--HVQVSK-NLQEILEYIGH---SVEKHR----ANLDPSN
-PRDFID-----------TYLLRMEK---------EKSNPH-TEFHHRNLM-ITVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLL
LKYPHVA-EKVQKEID---QVIGSH-RQPSLEDRHKMPYTEAVINEIQRFSDIIPAG-VP
HRVT-RD--TWFRGYLL--PK---------------------------------------
-----------------------DT-E-VYP--ILSSA-LHDP-KYFKQPDTFN-----P
DHFLDANGALK--KNEAFMPFSI-G-----------------------------------
-------------------------KRI-CL--GEGIAR--SELFLFFTTILQ-NFSVSS
PMAP---KDIDLSP-KEDGFA--------RVPP----E---------YQICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVL------L--FLALL--------------------TGL
LLLLV--Q--RHPN-THGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--K-SF----L--R-FREKYGD-VFTVHLGP----R-PVVMLCGVEA
I---REALVDKAEA-FSG--RGKIA---M-VDPF-FRGY----------G-----VIFA-
-NG--N-RWKVLRRFSVTTMRDF--GMGKRSVE--ERIQEEAQCLIEE------LR-KSK
----GA-L----M------------------------D-PTFLFQSI----TANIICSIV
FGKRFHYQDQ-EF-LKMLNLFYQTFSLVSS-----------VFG-----QL----F----
-ELFSG-FL----KYFP-GA--HRQVYK-NLQEINAYIGH---SVEKHR----ETLDPSA
-PKDLID-----------TYLLHMEK---------EKSDAH-SEFSHQNLT-LNTLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-ERVYREIE---QVIGPH-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMG-VP
HIVT-QH--TSFRGYII--PK---------------------------------------
-----------------------DT-E-VFL--ILSTA-LHDP-HYFEKPDAFN-----P
DHFLDANGALK--KNEAFIPFSL-------------------------------------
------------------------GKRI-CL--GEGIAR--AELFLFFTTILQ-NFSVAS
PEAP---EDIDLTP-QECGVG--------KIPP----T---------YQIRFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQL-----DI-R-----
----------NIS--K-SF----S--NV-SMLYIP-------------P-PTVVLHGYEA
L---KEALIDHGEE-FSE--RGALP---L-IERS-QKGH-----------G----IIFS-
-TG--K-RWKEMRRFSLLTLRNF--GMGKRSIE--DCVQKEARCIVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNMICSIV
FQNRFQYEDK-NF-LTLMERFNENFRIAST-----------PWI-----QV----C----
-NIFPF-LI----DYFP-GT--HNKFLK-NGAFTKSYILE---KVKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFTVENLV-STVFDLFV
AGT-HTTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYMDAVLHEIQRYIDLIPNG-LL
HTVT-SD--IKFRNYLI--PK---------------------------------------
-----------------------GT-N-IVP--SLTSV-LYDD-KEFPNPEVFD-----P
GHFLDESGNFK--KSENFMPFSA-GK----------------------------------
--------------------------RI-CI--GEGLAR--MELFLFLTTILQ-NFNLKS
LTDL---KALNATP-TAKGL-V-------SMLP----S---------YQICFTPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MC--T-S-------LMKISEHYGP-VFTIHLGP----R-RVVVLCGHDA
V---REALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLIEALRG-------TR
----GA-N----I------------------------D-PTFFLSRT----VCNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFHLKNLV-MTSLNLFF
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRVKMPYTEAVIHEIQRFGNVIPMS-LA
HRVI-RD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-RFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFLTTIMQ-NFGFES
PQLP---KDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--VLVLG-------------------LSC-
-LLLFSLW--RQSS-GRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----DI-T-----
----------DIS--K-SF----T--NF-SKAYGP-VFTLYFGM----K-PTVVVHGYEA
V---KEALDDLGEE-FSG--RGSFP---I-VEKT-NSGQ----------G-----IIFS-
-NG--T-KWKEIRRFTLMTLRNF--GMGKRSIE--DRIQEEACCLVEE------LR-KTN
----GS-S----C------------------------D-PTFILGCA----PCNVICSII
FQKRFDYKDE-NF-LILMQKFNENFKILNS-----------PWM-----QV----C----
-NIFPA-FI----DYLP-GS--HKKVLK-NFAHIKTYVLK---KVKEHQ----ESLDIHN
-PRDFID-----------CFLIKME-Q--------EKHSQH-SEFTIENLM-ATVTDLFI
AGT-ETTS-TTLRYGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYTDAMVHEIQRYINLIPNN-VP
RAAT-CN--LRFRNYFI--PK---------------------------------------
-----------------------GT-N-LIT--SLTSV-LHDD-QEFSNPEIFD-----P
GHFLDENSNFK--KSDYFMPFSI-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
LVDT---KDIETIP-IANTF-G-------HVPP----L---------YEICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVL------L--FLALL--------------------TGL
LLLLV--Q--RHPN-THDRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--K-SF----L--R-FREKYGD-VFTVHLGP----R-PVVMLCGVEA
I---REALVDKAEA-FSG--RGKIA---M-VDPF-FRGY----------G-----VIFA-
-NG--N-RWKVLRRFSVTTMRDF--GMGKRSVE--ERIQEEAQCLIEE------LR-KSK
----GA-L----M------------------------D-PTFLFQSI----TANIICSIV
FGKRFHYQDQ-EF-LKMLNLFYQTFSLISS-----------VFG-----QL----F----
-ELFSG-FL----KYFP-GA--HRQVYK-NLQEINAYIGH---SVEKHR----ETLDPSA
-PKDLID-----------TYLLHMEK---------EKSNAH-SEFSHQNLN-LNTLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-ERVYREIE---QVIGPH-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMG-VP
HIVT-QH--TSFRGYII--PK---------------------------------------
-----------------------DT-E-VFL--ILSTA-LHDP-HYFEKPDAFN-----P
DHFLDANGALK--KTEAFIPFSL-------------------------------------
------------------------GKRI-CL--GEGIAR--AELFLFFTTILQ-NFSMAS
PVAP---EDIDLTP-QECGVG--------KIPP----T---------YQIRFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSF-
-VLLFSLW--RQSS-GRRNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PFPIIGNM-------LQI-----DV-K-----
----------DIC--K-SF----S--NF-SKVYGP-VFTVYLGM----N-PVVVLHGYEA
V---KEALIDNAEE-FSG--RGILP---I-SERI-TKGL-----------G----IISS-
-NG--K-RWKETRRFSLTTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSVV
FQKRFDYKDE-NF-LTLMKRFTENFRILTS-----------PWI-----QV----C----
-NNFPL-LI----DCFP-GT--HNKLLK-NVALTKSYIRE---KVKEHQ----ATLDINN
-PRDFID-----------CFLIKME-K--------EKDNQQ-SEFTIENLV-GTVADLFV
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-SSPCMQDRSHMPYTDAVVHEIQRYIDLVPTG-VP
HAVT-TD--IKFRNYLI--PK---------------------------------------
-----------------------GT-I-IMT--LLTSV-LHDD-KEFPNPKIFD-----P
GHFLDENGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTTILQ-NFNLKS
VADL---KNLNTTS-ATRGI-I-------SLPP----S---------YQICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVLGV--FLGLV-------------------LSC-
-LLLLSLW--RQSS-QRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNI-------LQV-----DL-K-----
----------NIS--K-SL----R--DL-SKVYGP-VFTVYLGR----K-PAVVLHGYEA
V---KEALIDHGEE-FAG--RGSFP---V-FERL-KKGL-----------G----IAFS-
-NG--R-NWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSIV
FQNRFDYKDQ-DF-LNLMNNLNENVKIMSS-----------PWM-----QV----C----
-NNFPV-II----DRLP-GS--HTKLLK-NIISFKRYCLE---KVKEHQ----ESLDVNN
-PRDFID-----------CFLIKME-Q--------EKHNPK-AEFTYENLA-VTASDLFA
AGT-ETTS-TTLRYSLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VR----E---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSHMPYTDAVLHEIQRYIDLLPTS-LP
RAVT-CD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIT--SLTSV-LHDD-KEFPNPKRFD-----P
GHFLDENGKFK--KSVYSIPFST-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
PVDP---KDLDTTA-VANGF-V-------SVPP----E---------FQICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDSLV--VLVLC-------------------LSC-
-LLLLSLW--RQRS-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNI-------LKI-----GI-K-----
----------DVS--K-SL----T--NL-SKVYGP-VFTLYFGL----E-RMVVLHGYEA
V---KEALIDLGEE-FSG--RGHFP---L-FERA-NRRF-----------G----IVFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FHKRFDYKDQ-QF-LNLMEKFNENAKILSS-----------PWI-----QI----Y----
-NNFSP-II----DYFP-GT--HNKLLK-NIAFVKSYILE---KVKEHQ----ESMDMNN
-PRDFID-----------CFLIKME-K--------EKHNQQ-SEFNIENLE-NTAVDLFA
AGT-ETTS-TTLRYALLLLLKHPEVA----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---HVIGRN-RSPCMQDRSHMPYTDAVVHEIQRYIDLLPTS-VP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-ILI--SLTSV-LRDN-KEFPNPEMFD-----P
SHFLDEGGNFK--KSNYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLFLTSILQ-NFNLKS
LVDL---KDLDTTP-VFNGF-V-------SVPP----V---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
IMVLMSVW--RQR-NLKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISERYGP-VFTIRLGT----R-QIVVLCGYDA
V---KEALVDQAEE-FSG--RGVQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIEAFRG-------TR
----GT-F----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFYS-VM----KYLP-GP--QQQAFK-ELQGLEDFIAK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EKENPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTMRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDMIPMG-LA
RRVT-KD--TKFRDFLL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPRDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFFTTIMQ-NFRFKS
PQSP---QDINVSP-KLVGFA--------TIPP----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--ALVLC-------------------LSC-
-LFLLSLW--RQSS-GRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PSGPT---PLPIIGNI-------LQL-----DV-K-----
----------DMS--K-SL----T--NF-SKVYGP-VFTVYFGL----K-PIVVLHGYEA
V---KEALIDHGEK-FSG--RGSFP---V-AEKV-NKGL-----------G----ILFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEALCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSVI
FHNRFDYKDQ-RF-LNLMEKFNENLRILSS-----------PWI-----QV----C----
-NNFPA-LI----DYLP-GS--HNKVVK-NFAYVKSYVLE---RIKEHQ----ESLDMDN
-PRDFID-----------CFLIKME-Q--------EKHNLQ-SEFTIESLI-ATVTDMFG
AGT-ETTS-TTLRFGLLLLLKYPEIT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---CVVGRN-RSPCMQDRSHMPYTDAVVHEIQRYIDLIPTN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-IIT--SLTSV-LHND-KEFPNPEMFD-----P
GHFLDRSGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
QVDP---KDIDITP-IANAF-G-------RVPP----F---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MGALGIT-----I--ALLVW-------------------VVT-
-LLLISIW--KQLY-SSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNL-------LQL-----DI-K-----
----------DIP--K-SF----T---RLAKRYGP-VFTLYLGS----R-RTVILHGYKA
V---KEVLLTHKNE-FSG--RGEIPVFQE----YKDKG-----------------IIFN-
-NG--P-TWKDVRRFSLSILRDY--GMGKQGNE--ARIQREAQFLVQE------LR-NTQ
----GR-P----F------------------------D-PTFLLGCA----PCNVISDIL
FHRRFDYKDK-TI-LRLMSLFNENFYLLST-----------PWL-----QL----Y----
-NNFSN-YL----RYMP-GS--HRKIMK-NASEIKVYALE---RAKEHL----QSLDPSC
-PRDVTD-----------CLLIEMEK---------EKHREKPPMYTMENIS-VTLADLFF
AGT-ETTS-TTLRYGLLILMKYPEVE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPT-RIPAIKDRLEMPYMDAVVHEIQRFINLVPSN-LP
HEAT-QD--TMFRGYLI--PK---------------------------------------
-----------------------GT-V-VIP--TLDSL-LYDS-QEFPDPEQFK-----P
EHFLNENGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLLLTAILQ-NFNLKS
LVEP---KDIDLKP-ITIGF-G-------CVPP----H---------YKLCVIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------M--VLVLC-------------------LSC-
-LYLLSFW--RHSS-GRGKLPPGPT---PLSIIANI-------LQI-----DA-K-----
----------NIN--K-SL----T---HFSKVYGP-VYTVYLGM----K-PTVVLHGYEA
V---KEALVDLGDK-FSG--RGSLP---V-FEKT-GKGL----------G-----ITFS-
-NG--K-MWKEIRPFSLMILRNL--GMGRRSIE--DCVQEEARYLVEE------LR-KTN
----GG-SDGHLG------------------------S----------------------
------FQD-----LAITNCASVNMSVH

PF00067 // ENSGT00880000137861_0_Domain_2 (569, 1252)

IS-----------LWY-----DI----F----
-NSFGK-------IPRR-ES--HNRIFK-NTVYIRNYILD---KEKEHQ----ASLDISN
-PKDFID-----------CFLIKME-Q--------EKHNQQ-MEFTCENLL-VTVSNLFV
AGT-ETTS-TTLRYVLLLLIKHPQVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRQ-RSPCMQDRSHMHYTDAVLHEIQRYINLFPNS-LP
HAVT-CD--IKFRNYLI--PK---------------------------------------
-----------------------VRFSLILT--SLTSV-LHDD-KEFSNPETFD-----P
HHFLDESGKFK--KSDYFMPFST-GN----------------------------------
----------------------RSLKWM-CL--GEGLAC--MELFLFLTTILQ-HFNLKS
VVDP---KYLETTP-IVNGF-V-------SLPP----L---------YKLCFIPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------EEK-APMDLAV--VLVLC-------------------LSC-
-LLLLSLW--KQSS-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPILGNI-------FQL-----DV-K-----
----------NIS--K-SL----T--SL-SKVYGP-VFTVYFGM----K-PTVVLHGYEA
V---KEALIDLGEE-FSG--RGSFP---V-IQRT-VKGY-----------G----IVFS-
-NG--K-TWKETRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GL-P----C------------------------D-PTFILGCA----PCNVICSII
FQNRFDYKDQ-SF-LNLMKTVNENIKILGS-----------PWM-----QV----L----
-NIFPV-LL----DFFP-WS--YKKFST-NIAYVKNYVLE---KTREHQ----ASLDINN
-PRDFID-----------CFLIKME-Q--------EKHNHQ-SEYTFENLT-IAVSDLFG
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-IQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRTRMPYMDAVVHEIQRYIDLAPTS-VP
HAVN-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-D-ILT--SLTSV-LYDD-KEFPNPEVFD-----P
GHFLDENGNFR--KSDYFMAFSA-GK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLFLTTILQ-KFTLKS
LVDP---KDIDTTP-AVTGI-A-------NVPP----P---------YQVCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLDTGL----LLV--VILAS-------------------LSVM
FLVS--LW--QQ--KIRERL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPFIGNY-------LQL-----NM-K-----
----------DVY--S-SI----T---QLSERYGP-VFTIHLGP----R-RIVVLYGYDA
V---KEALVDQAEE-FSG--RGELP---T-FNIL-FKGY----------V-----FKFS-
-HH--V-ESQKKKKIVIQQFPEL--LTLSRDDE--NRKLEECLASVAG------LR-HTL
----LV-P----L------------------------D-SSDYLTPT----PINVVTGPK
RIRRFTIATLRDFGCHSHSMLPLTSLFFSP-----------PTP-----QL----Y----
-DMFHS-VM----KYLP-GP--QQQIIK-VTQKLEDFMIE---KVRQNH----STLDPNS
-PRNFID-----------SFLIRMQE----------EKYV-NSEFHMNNLV-MSSLGLLF
AGT-GSVS-STLYHGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
-------AK-VH----E---E---------------------------------------
--------------IE---RVIGRN-RQPQYEDHMKMPYTQAVINEIQRFSNLAPLG-IP
RRII-KN--TTFRGFFL--PKGT-------------------------------------
--------------------------D-VFP--IIGSL-MTEP-KFFPNHKDFN-----P
QHFLDDKGQLK--KNAAFLPFSI-------------------------------------
------------------------GKRF-CL--GDSLAK--MELFLLLTTILQN-FRFKF
PMNL---EDINEYP-SPIGFT--------RIIP----N---------YTMSFMPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLALGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------IMKISERYGP-VFTIHLGP----R-RVVVLCGYDA
V---KEALVDQAEE-FSG--RGEQATFNW----V-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEADFLIEALRG-------TH
----GA-N----I------------------------D-PTFFLSRT----VCNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTST-----------SMG--Q---L----H----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFYMQNLL-MTALNLFI
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVISKN-RQPKFEDRVKMPYMEAVIHEIQRFGNVIPMS-LA
RRVN-KD--TKFRDFFL--PKST-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-KFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFFTTIMQ-NFRFKS
PQSP---KDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFI--VLVIY-------------------L---
----------------SWKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIVGNI-------LQI-----NT-N-----
----------NVS--K-SI----S--KL-AESYGP-VFTVYFGI----K-PTVVIYGYEA
V---KEALIDQSEV-FSG--RGPFP---V-LDKF-IQGL-----------G----IIFS-
-NG--E-QWKQVRRFSLMVLRSM--GMGKKSIE--DRIQEEALYLVEA------LK-KTN
----AS-P----C------------------------D-PTFLLGCA----PCNVICSVV
FQNRFEYDDE-KF-SILINYFHGNLLISTYRTLLSELMSDSFLF-----QL----C----
-NAFPL-LI----HF-P-GC--HNVLLK-NIANQCKFIVE---KIKEHQ----ESLDLSN
-PRDFID-----------YFLIKIE-K--------EKHNKQ-SEFTMDNLI-FTVWDVIS
AGT-ETMS-TTLRYGLLLLLKHPEVR----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVVGRH-WSPCMQDRSHMPYTDAVVHEIQRFIDLVPNS-LP
HSVT-QD--TKFREYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDD-KEFPNPDQFD-----P
GHFLDESGNFK--KSDYFLAFS-AGK----------------------------------
--------------------------RV-CI--GEGLAR--MELFLLLTNILQ-HFTLKS
VVDP---KDLETAP-IVNGV-G-------AAPP----V---------YKLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPIL--VLVLI-------------------LSC-
-LFLLSLW--RQSY-ERGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1106)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------DIC--Q-SF----T--NL-SRVYGP-VYTLYLGR----K-PTVVLHGYEA
V---KEALVDHGDV-FAG--RGRLP---V-FDKA-TNGM----------G-----IGFS-
-NG--S-VWKNTRHFSLMTLRNL--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FQDRFDYKDR-DF-LNLLEKLDEISKILST-----------PWL-----QV----C----
-NTFPA-LL----DYCP-GS--HNQFFK-NYAYIKNFLLE---KIREHK----ESLDVTI
-PRDFID-----------YFLIKGA-Q--------EDGNHP-LKNNFEHLA-ITVTDLFI
GGT-ESMS-TTLRYALLLLLKYPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---HVIGKH-RSPCMQDRNHMPYTNAMIHEVQRFIDLVPNN-LP
HEVT-CD--IKFRNYFI--PK---------------------------------------
-----------------------GT-T-VIT--SLSSV-LRDS-KEFPNPEKFD-----P
GHFLDENGKFK--KSDYFMPFST-GN----------------------------------
--------------------------KC-DP--LLST-------CLIGY-----------
L-LS--HLSI--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDSLV--VLVLC-------------------LSC-
-LLLLSLW--RQRS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNI-------LQI-----DI-K-----
----------DVS--K-SL----T--NL-SKVYGP-VFTLYFGL----E-RMVVLHGYEA
V---KEALIDLGEE-FSG--RGHFP---L-ADRA-NRGF-----------G----IIFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSIV
FHKRFDYKDQ-QF-LNLMEKFNENTKIASS-----------PWI-----QI----C----
-NNFPP-FI----DYFP-GA--HNKILK-NIAFVKSYILE---KVKEHQ----ESMDMNN
-PRDFID-----------CFLIKME-K--------EKHNQQ-SEFTIENLE-NTAVDLFT
AGT-ETTS-TTLRYALLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRN-RSPCMQDRSHMPYTDAVVHEVQRYIDLLPTN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-ILI--SLSSV-LHDN-KEFPNPEMFD-----P
RHFLDEGGNFK--KSNYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTSILQ-NFNLKS
LVDP---KDLDTTP-VLNGL-A-------SVPP----F---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------M----K

PF00067 // ENSGT00880000137861_0_Domain_2 (350, 1252)

-PSVVLHGYEA
V---REALIDLGEE-FAG--RGSFS---V-PEKV-NKGL-----------G----ILFS-
-NG-------------------------NRSIE--DRVQEEARCLVEE------LR-KTS
----GA-P----C------------------------E-PTFILGCA----PCNMICSII
FQRCFDYKDQ-NF-LNLMEKLNENLRLLSS-----------PWI-----QV----C----
-NTFPF-II----DYLP-GI--HKKILK-NFDYVKSYVLE---RVKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKHNQQ-SEFTTESLI-ATVTDMFG
AGT-ETTS-TTLRYGLLLLLKHT-------------------------------------
------------------------------------------------------------
-----------E----E---E---------------------------------------
--------------ID---RVIGRQ-RSPCMQDRSHMPYTDAVVHEIQRYIDLIPNN-LP
HAVT-RD--IKFRDYFL--PK---------------------------------------
-----------------------GT-T-IIT--SLTSV-LHYD-KEFPNPEIFD-----P
GHFLDESGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RM-CA--GEGLAH--MELFLFLTTILQ-NFNLKP
LVDP---KDIDTTP-VASGF-G-------HVPP----F---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------GL-------------------GLS-
-LVLLSLW--KGNS-VKGKLPPGPT---PLPIIGNI-------LQL-----NT-K-----
----------NIV--K-SL----S---ILAKKYGP-VFTVYLGM----R-PTVVLYGYKA
V---KEALIDRAEE-FGG--RGSFP---V-MDKA-IQGL----------G-----MFLY-
-WG--E------------LLRNM--GMGKKTIE--DKIQEEAFFLL--------------
--------------------------------------------AC--------------
--N

PF00067 // ENSGT00880000137861_0_Domain_2 (544, 1252)

HFDYSDQ-KL-HALIESFHDNLRILST-----------SWV-----QL----C----
-NAFP--AL----LYLP-GS--HNKLFK-NIAHQKNIILG---KVKEHK----EALDPSN
-PQDFID-----------YFLIQME-K--------EKHNKQ-SEFTMDNLI-TTCWDVFS
AGT-ETTS-TTMTYGLLLLLKHPEIS----------------------------------
------------------------------------------------------------
-------VK-IH----E---E---------------------------------------
--------------IP---RVIGRH-RSPSMQDRSSMPYTDAVVHEIQRYIDILPIN-MP
HVVT-KD--IQFRDFFI--PK---------------------------------------
-----------------------GT-K-ILT--SLNSV-LHDE-KAFPNPEQFD-----P
SHFLDASGNFQ--KSAPFMAFPA-GK----------------------------------
--------------------------PV-CL--GESLAR--MELFLVLTHILQ-NFTLKS
LVDP---QDIDTSP-AAIGI-G-------SVPP----L---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSKGKLPPGPT---PLLFIGNY-------LQL-----NTEQ-----
-----------MC--T-S-------IMKISERYGP-VFTIHLGP----R-RVVVLCGHDA
V---REALVDQAEE-FSG--RGEQATFNL----F-FKG--------------YYGVTFS-
-TL--E-RAKLLRHFSIATLRNF--G-----EK--A------GFLIQALL--------GT
----RG-E----I------------------------N-PTFFLSRT----VSNV

PF00067 // ENSGT00880000137861_0_Domain_2 (536, 1107)

ISSI-
------------F--------------TAT-----------STG-----QL----Y----
-EMFSS-VM----THLP-GP--QQQTFK-ELQGLEDFIAK---KVEHNQ----RTLDPSS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFYMQNLV-MTALNLFI
AGT-ETIS-TALRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEETD---RVIGKN-RQPKFEDQARMPYTEAVIHEIQRSGDVIPMA-VA
HRVN-KD--TKFQDVFL--LKGT-------------------------------------
--------------------------E-MFP--MLGSV-LRDPQVLLQPPGLQSP-----
-------RQFK--KSDAFVPFSI-GKRPLFAARPLSKPQVYQNFSLLSASSSFDLI----
--------KF--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDAVL--VLLLS-------------------LPC-
-LLLLSLW--RRGS-GRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNT-------LQI-----DF-K-----
----------NLN--K-SL----N--NF-SKVYGP-VFTLYLGM----Q-PTVVLHGYDA
V---KEALIDHGEE-FSG--RGRLP---L-VDKA-NRGF-----------G----IAFS-
-NG--S-TWREMRRFSLMTLRNF--GMGKRSIE--ECVQEEALCLVEE------LR-KTK
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FKNRFAYKDP-EF-LNLIEKLNENIKVLSS-----------PWI-----QV----C----
-NKFPV-LM----DYLP-GS--HDTLLK-NFAYLKNYFMD---KVREHE----ETLDVNN
-PQDFID-----------CFLIKMK-Q--------EKDNHQ-SEFNYENLA-CTINNLFG
AGT-ETTS-TTLRYSLLLLMKHPHIT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSQMPYTDAVLHEIQRYIDLLPTN-LP
HAVT-CD--AKFRNYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDN-KEFPNPEIFD-----P
GHFLDKSGNFT--KSDYFMPFST-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFKLKP
LVDP---KDIHTIP-VANGF-A-------ALPP----S---------YQLCFISV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
IMVLMSVW--RQR-NLKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1170)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MC--N-S-------LMKISEHYGP-VFTVHLGT----R-QIVVLCGYDA
V---KEALVDQAEE-FSG--RGKQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIEAFRG-------TR
----GA-F----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFYS-VM----KYLP-GP--QQQAFK-ELQGLEDFIAK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EKENPN-TEFYRKNLV-MTTLNLFF
AGT-ETVS-TTMRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDMIPMG-LA
RRVT-KD--TKFRDFLL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPRDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRH-C------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (416, 1071)

MAFS-
-NG--E-RAKQLRRFSITTLRNF--GVGKRGIE--ERILEEAHFLLEALRG-------TK
----GL-P----F------------------------D-PTYFLSRS----VSNVISSVV
FGDRFDYEDK-EF-LSLLYMITESFRFTAT-----------AWG-----QL----Y----
-EMFSG-TM----CYLP-GP--QREAFK-QLAGLEQFIQR---KVKANL----ESLDPSA
-PRDFID-----------CFLVKMQQ---------EQENPA-SEFSLKNIV-LTTLSVFF
AGT-ETVS-TTLRYGLLILLKHPEIE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------EKIHEEID---RVIGRN-RAPSMEDRSHMPYTDAVIHEFQRFCDVIPMG-LA
RRVT-RD--TPFRGYII--PKGT-------------------------------------
--------------------------E-VYP--VLGSV-LHDP-SQFSAPE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAVLGIT-----V--ALLCW-------------------LAI-
-LLLVSVW--KQVH-SSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIVGNL-------LQL-----EL-K-----
----------NIP--K-SL----N---KMAERFGP-VFTLYLGP----R-RVVVLHGYKA
V---REALLDHKSE-LSG--RGYIPAFQE----HRNKG-----------------VIFN-
-NG--P-TWKDTRRFSLMVLRDY--GMGKQGNE--ERIQREIPFLLEE------LR-KTK
----GQ-P----F------------------------D-PTFVIGCA----PFNVIADIL
FCKHFDYNDK-KC-LRLMSLFNENFYLLST-----------TWL-----EF----Y----
-NNFSS-YL----HYLP-GS--HRKVLK-NVSEIREYVSA---RLKEHH----QSLDPTC
-PRDFTD-----------CLLAEMEK---------RKHSAE-PLYTLDNIS-VTVADMFF
AGT-ETTS-TTLRYGLLILMKHPEIE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RVPATKDRMQMPYMDAVVHEIQRFISLVPSN-LP
HEAT-QD--TRFRGYVI--PK---------------------------------------
-----------------------GT-T-VIP--TLTSV-LHDS-KEFPEPEKFK-----P
EHFLDERGKFK--YSDYFKPFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLFLTAILQ-NFNLKS
LVHP---KDIDLSP-MTIGF-G-------NVPP----H---------YKLCVIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAALGIT-----V--ALLVW-------------------MAT-
-LMLISIW--KQIY-SRWKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNI-------LQV-----DI-K-----
----------NVP--K-SL----A---KLAEQYGP-VFTLYLGS----Q-RTVVLHGYKA
V---KEVLLDHKND-LSG--RGEVFAFQS----HKDRG-----------------ITFN-
-NG--P-GWKDTRRLSLSTLRDY--GMGKRGNE--ERIQREIPFLLEA------LR-GTR
----GQ-P----F------------------------D-PTFLLGFA----PFNVIADIL
FHKHFDYSDQ-TG-LRIQKLFNENFHLLST-----------GWL-----QL----Y----
-NIFPS-YL----HYLP-GS--HRKVLR-NVAELKDYSLE---RVKEHQ----ESLDPTC
-SRDFTD-----------CLLQELQK---------ERYGTE-PWYTLDNIA-VTVADLFF
AGT-ETTS-TTLRYGLLILMKYPEVE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RVPAIKDRLEMPYMDAVVHEIQRFIDLLPSN-LP
HVAN-QD--TMFRGYVI--PK---------------------------------------
-----------------------GT-V-VIP--TLDSV-LFDK-QEFPDPEKFK-----P
EHFLNENGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLFLSAILQ-HFNLKS
LVDP---KDIDLSP-CTIGF-A-------KIPP----H---------YKLCVVPRSG---
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSF-
-VLLFSLW--RQSS-GRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1168)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------DIC--K-SF----S--NF-SKVYGP-VFTVYFGM----N-PVVVLHGYET
V---KEALIDNAEE-FSG--RGILP---I-SERI-TNGL----------G-----IISS-
-NG--K-RWKETRRFSLTTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILSCA----PCNVICSVV
FQKRFDYKDE-NF-LTLMKRFTVNFRILTS-----------PWI-----QV----C----
-NNFPL-LI----DCFP-GT--HNKLLK-NVALTKSYIRE---KVKEHQ----ATLDVNN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFTIENLV-GTVADLFV
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSHMPYTDAVVHEIQRYIDLVPTG-VP
HAVT-TD--IKFRNYLI--PK---------------------------------------
-----------------------GT-I-IMT--LLTSV-LHDD-KEFPNPKIFD-----P
GHFLDENGNFK--KSDYFMPFSA-GN----------------------------------
--------------------------RI-SF--PFAFEG--KR------ELF----GISW
--NL---H---GTP-S----------------G----A---------GRIAICP------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVLGV--FLGLV-------------------LAC-
-LLLLSLW--RQNS-QRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQV-----DL-K-----
----------NIS--K-SL----R--DL-SKVYGP-VFTLYLGS----K-PAVVLHGYEV
V---KEALIDHGEE-FSG--RGSLP---A-VDKI-KKGL-----------G----IIFS-
-NG--K-NWKETRRFSLMTLRNF--GMGKRSIE--ERVQEEARCLVEE------LR-KTN
----GA-P----C------------------------D-PTFILGCA----PCNVICSII
FQNRFNYKDQ-DF-LNLINILNENANILSS-----------PWM-----QV----C----
-NNFPV-IT----DYLP-GS--HAKLLK-NFTFLKHYCLE---KVKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKHNSN-VECTYDNFA-VTTSDLFA
AGT-ETTS-TTLRYSLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRN-RSPCMQDRTHMPYTDAVLHEIQRYIDLVPTS-LP
HATT-SE--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIT--SLTSV-LNDD-KEFPNPERFD-----P
GHFLDENGKFK--KSDYFFPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFHLES
PVDP---KDLDTTP-VVSGL-I-------AVPP----K---------FQICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLAFF--------------------AGF
LLLLV--R--GHPK-ARGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQM-----DR-R-----
----------GLL--N-SF----M--R-LRDKYGD-VFTVHLGP----R-PVVMLYGTEA
I---REALVDQAEA-FSG--RGTIA---V-VKPT-FKDY----------G-----VIFA-
-NG--E-RWKALRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLSPV------LPLHPP
----GA-P----L------------------------D-PKFLFQCI----TANIICSIV
FGERFDYKDR-QF-LRLLELFYRSFSLISS-----------FSS-----QV----F----
-ELFSG-FL----KYFP-GT--HKQIYR-NLKEILDYIDH---SVDKHR----ATLDASN
-PRDFID-----------TYLLRMEK---------EKSNSH-TEFHHQNLI-ISVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVIGSH-RLPTLDDRTKMPYTDAVIHEIQRFSDLIPIG-VP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------DT-E-VYP--ILSSA-LHDP-QYFEQPDTFN-----P
DHFLDANGALK--KNEAFMPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTLLQ-NFSLSS
PVDP---KDIDLNP-KESGFG--------RVPP----E---------YQICFLSR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------RTICTMEWVYV----VTL--LLVIC-------------------VSCH
LLISS--K--RK-QLQKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1248)

PPGPT---PLPLIGNF-------LQM-----KS-G-----
----------ETL--K-SL----L---KMYEKYGP-VFTVYLGT----H-PVLVLCGHQA
V---KEALIDKAEE-FCG--RTIKP---T-LESA-VEG----------YG-----VGFS-
-SG--E-RWKQLRRFSITVLKSF--GMGKKSIE--ERIQEEAQFLMEE------FR-KTK
----GK-P----V------------------------VLQENLLGCA----TSNIISSIV
FGERFDYENE-EF-QALMRMINNFFWEIST-----------TWS-----QL----Y----
-DMFPT-LL----KYFP-GP--HTRVYN-ILSDMFLFVAK---RVEKNQ----ETLDSNF
-PRDFID-----------CFLIQME-K--------EKDNPL-SEFNIKNLE-HTIFNLFF
GGT-ETVT-STLKYGFLLLMKYPEVQ----------------------------------
------------------------------------------------------------
-------AK-VH----E---E---------------------------------------
--------------ID---RVIGHN-RIPNSEDRRQMPYTDAVIHEIQRVSDLVPMS-VA
HMVT-CD--TEFRGYFI--PK---------------------------------------
-----------------------GM-E-VWP--VLSTV-LHDP-TMFKSPSVFN-----P
ENFLDENGCFK--KNDAFVPFST-GK----------------------------------
--------------------------RT-CL--GESLAR--MELFLFFTIILQ-SFQLKP
LVPP---EDLDPTP-LENGF-L-------TVPP----F---------YHLSIIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MSALGIT-----V--ALLVW-------------------AAI-
-LLLVSIW--RQVH-SGWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 745)

PPGPF---PLPIVGNL-------FQL-----EL-K-----
----------NIP--K-SF----T---QLAERFGP-VFTLYLGA----R-RVVVMHGYKA
V---REALLDYKSE-FSG--RGEIPAFQA----HKDRG-----------------IIFN-
-NG--P-TWKDIRRFSLTTLRNY--GMGKQGNE--NRIQREAHFLVEA------LR-KTQ
----GQ-P----F------------------------D-PTFLVGCA----PCNVIADIL
FRTRFEYDDE-KF-LRLMHLFNENFYLLST-----------PWL-----QL----Y----
-NNFSS-YL----HYLP-GS--HRKVIR-NVAEIKEYVSE---RVKEHH----QSLDPNC
-PRDLTD-----------CLLVEMEK---------EKPSAE-PLYTMDGIT-VTVADLFF
AGT-ETTS-TTLRYGLLILMKYPEIE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
IMVLMSVW--RQR-KLAGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKLRDRYGP-VFTVYLGA----R-RVVVLCGQDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIEAFRN-------TR
----GA-F----I------------------------D-PTFYLSRT----VFNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFYP-VM----KHLP-GP--QQQAFK-ELQGLEDFITK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMRE---------EQKNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTMRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYVEAVIHEIQRFGDMIPMG-LA
RRVT-KD--TKFRGFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFARPRDFN-----P
QHFLDENGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTIMQ-NFRFKS
PQAP---QDIDVSP-KHVGFA--------TIPP----T---------YTMSFQPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (416, 1252)

IAFS-
-NG--E-RWKALRKFSVQILRNF--GVGKRSIE--ERILEEGSFLLAE------LR-KTK
----GE-P----F------------------------D-PTFVLSRS----VSNIICSVL
FGSRFEYEDE-RL-LTIIQLINDNFQIMSS-----------PWG-----EM----Y----
-NIFPN-LL----DWVP-GP--HRRLFQ-NYGRMKDLIAG---IVQEHQ----TSLDPSS
-PRDFID-----------CFLTKIA-Q--------EKQDPL-SHFFMDTLL-ITTHNLLF
GGT-ETVG-TTLRHTFLVLMKYPKVQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---RVVGRA-RLPCMEDRKAMPYTDAVIHEVQRFADVIPMN-LP
HRVI-RD--TNFRGFLL--PK---------------------------------------
-----------------------GT-D-IIT--LLNTV-HF-P-SQFLTPKEFN-----P
GHF-DDNQSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GESLAR--MELFLYLTAILQ-SFSLQP
QGAP---EDIDLTP-LSSGL-G-------NLPR----P---------FQLTLRAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDGIST----AIL--LLLLA-------------------LVCL
LLT-L------S-SRDKRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LLL-----RS-Q-----
----------NML--T-SL----T---QLSKEYGS-VYTVHLGP----R-RVVVLSGYQA
V---KEALVDQGEE-FSG--RGDYP---V-FFNF-TKGN----------G-----IVFS-
-NG--D-RWKVLRRFSIQILRNF--GMGKRSIE--ERILEEGSFLLAE------LR-KTE
----GE-P----F------------------------D-PTFVLSHS----VSNIIWSVL
FASRFHYDDE-RL-LTIIRLINDNFQIMSS-----------PWG-----EL----Y----
-NIFPS-LL----DWVP-GP--HQRIFQ-NFKRLRDLIAH---SVHDHQ----ASLDPRS
-PRDFID-----------CFLTKMA-E--------EKEDPL-SHFHMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFLALMKYPKVQ----------------------------------
------------------------------------------------------------
-------AR-MQ----E---E---------------------------------------
--------------ID---LVVGRS-RLPTLEDRAAMPYTDAVIHEVQRFADIIPMN-LP
HRVI-RD--TAFRGFLI--PK---------------------------------------
-----------------------GT-D-IIT--LLNTV-HYDP-SQFLTPQEFN-----P
EHFLDANQSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GESLAR--MELFLYLTAILQ-SFSLQP
LGAP---EDIDLTP-LSSGL-G-------NLPR----P---------FQLCLCPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAALGIT-----V--ALLVW-------------------MAT-
-LLLISIW--KHIY-SSWKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNL-------LQL-----DI-K-----
----------NIP--K-SF----T---RLAERFGP-VFTLYLGS----R-RVVVVHGYKP
V---KEVLLDYKNE-FSG--RGENPGFQV----HKNNG-----------------IIFN-
-NG--P-TWRDTRRFSLTILRDL--GMGKQGNE--QRIQREAHFLLDV------LR-KTQ
----GQ-P----F------------------------D-PTFVIGFA----PYNVISDIL
FHKRFDYKDK-MG-LRLMSLFNENFYLLST-----------PWI-----QL----Y----
-NNFSD-YL----QYLP-GS--HRKLLK-NVSEVKDYALE---RTKAHQ----KSLEPSC
-PRGFLD-----------TMLIEMAK---------EKHSAD-PMYTLENIA-VTVADLLF
AGT-ETTS-TTLRYGLLILMKYPEVE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RIPAIKDRLDMPYLDAVVHEIQRFIDLIPSN-LL
HEAT-QD--TVFRGYVI--PK---------------------------------------
-----------------------GT-L-IIP--TLDSV-LYDR-QEFPEPEEFK-----P
EHFLNESGKFK--YSDHFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLFLAAILQ-HFNLKS
LVDP---KDIDLSP-IAIGF-G-------KIPP----R---------YKLCLIPRSEV--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MQPR-DLPLMSL--ILVIC-------------------LSI-
-LIFLFLW--NQKH-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1222)

PPGPT---PLPIVGNI-------LQI-----NI-K-----
----------NIS--K-SI----S--KL-AEDYGP-VFTLYFGM----K-PTVVLHGYEA
V---KQVLIDQSEE-FSG--RGSLP---V-ADNI-NQGL-----------G----IIFS-
-NG--E-QWKQTRRFSLMILRNM--GMGKRTIE--HRIQEEALCLVEA------LK-KTN
----GS-P----C------------------------D-PTFLLTYA----PCNVICSII
FRNRFEYSDE-NF-LTLAKYIHENATIFST-----------PWI-----EL----Y----
-NAFPS-LL----HYLP-GS--HNTLFK-NMTEQRKFILE---RIKEHQ----ASLDLNN
-PQDFID-----------YFLIKME-K--------EKHNKQ-SEFTMDNLI-TTVWDVFT
AGI-ETTS-ITLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IY---RVVGRN-RSPCMQDRSRMPYTDAVIHEIQRYIDLVPNN-LP
HAAA-QD--IEFREYLI--PK---------------------------------------
-----------------------GT-T-ILP--SLTSV-LHND-KEFPNPEKFD-----P
GHFLDKSGNFK--KSDYFMAFS-AGK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLLLVSILQ-QFTLKP
LVDP---KNIDTTP-LLKGS-G-------SIPH----F---------YEVCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------I-------------------------------
---------------ELSEFTV-TSMDPIV--VLVLL-------------------LSC-
-LLLISLW--RPTS-GRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNA-------LQI-----DF-K-----
----------DVS--K-TL----A--EF-SKVYGP-VFTLYLGM----K-PTVVLHGYEA
V---KEALVDNGEE-FAG--RDSIP---I-FERC-NKGL----------G-----IAFN-
-NG--K-TWKEIRQFSLMSLRYL--GMGKRSIE--DRIQEEARCLVEE------LK-KNN
----GS-P----C------------------------D-PTFNLSSA----VCNVINTTI
FHNRYDYNDP-CF-LDLMQRLNEIFRILGS-----------QWI-----QI----Y----
-NTFPA-LI----NCLP-GS--HNILFK-NVKYMQNYLLE---KVKEHE----ESLDVNN
-PRDFID-----------YFLIKMK-T--------EKDNQK-LAFTYENLV-ITAFDLWI
ASS-ETTS-ITLKYALLLLLKYPQVT----------------------------------
------------------------------------------------------------
-------AK-LQ----E---E---------------------------------------
--------------IQ---RVIGKH-NSPCMQDRNHMPYTNAVLHEIHRYINLSPIG-IP
HSVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-P-IWI--SLTSV-LYDN-KEFPHPEIFD-----P
HHFLDEHGKFK--KSDYFIPFSS-GK----------------------------------
--------------------------RK-CM--GESLAN--MELFLFLTTILQ-HFHLKS
LVNP---KDLDVTP-VANGI-Q-------YLPP----S---------YQLCFIPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDSIST----AML--LLLPA-------------------LVCL
LLTL-------S-SGDKGKDPDPSH---SWETC---------------------------
-----------LT--L-AR--V-----RLSKEYGS-MYTVYLGS----R-QVVVLSGFQA
V---KEALVDQGEE-FSV--HGDYP---V-FFNF-TKGN----------G--------K-
-KK-CV-VWYLLR--SIQLLDGQ--MSGELSCT--------SRLPDPS------HP-SPS
----

PF00067 // ENSGT00880000137861_0_Domain_2 (485, 1251)

GE-P----F------------------------D-PTFVLSRS----VSNIICFVL
FGSRFN-DDD-RL-LTIIRLNNDNFQLMSS-----------PWG-----EL----Y----
--IFPS-LL----DWVP-GP--HGRIFQ-NFKCLRDLIAH---SVHDHQ----ASLDPRS
-PRDFID-----------CFLTKTAE---------EKEDP-QSHFHMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFLALIKYPRVQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------IN---LVVGRA-WLPALEDRAAILYPDAVIHEVQRFADIIPMN-LP
HRVT-RD--TAFRGFLI--PKPSHTANS--------------------------------
-----------------TSSPTRGT-D-IIT--LLNTV-HHDP-SQFLMPQEFN-----P
EHFLDAKQSFK--KSPAFMPFSA-------------------------------------
------------------------GRRL-CL--GESLAR--MELFLYLTATLQN-FSLQP
LGAP---EDIDLTPAFSSGLG--------NLPR----P---------FQLCLRAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFV--VLVIC-------------------LSI-
-LIFLFLW--NQRH-AKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1222)

PPGPT---PLPIVGNI-------LQI-----NI-K-----
----------NVS--K-SI----S--KL-AEDYGP-VFTLYFGM----K-PTVVLHGYEA
V---KQVLIDQSEE-FSG--RGSLP---V-ADNI-NQGL-----------G----IVFS-
-NG--E-IWKQTRRFSLMVLRNM--GMGKRTIE--HRIQEEALCLVEA------LK-KTN
----GS-P----C------------------------D-PTLLLSCA----PCNVICSII
FRNRFEYNDE-RL-LTLIKYFNENSRLVST-----------PWV-----EL----Y----
-NTFPS-LL----HYFP-GS--HNTIFK-NMTEQRKFILE---EIKKHQ----ESLDLNN
-PQDFID-----------YFLIKME-K--------EKHNKH-SEFTMDNLI-TTVWDVFS
AGT-ETTS-LTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVVGRN-RSPCMQDKSCMPYTDAVLHEIQRYIDLVPSS-MP
HAAT-QD--VKFREYLI--PK---------------------------------------
-----------------------GT-V-ILT--SLTSV-LHDD-NEFSNPGQFD-----P
GHFLDESGNFK--KTDHFMAFS-AGK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLLLVSILQ-HFTLKS
VVDP---KHIDTAP-SFKGL-I-------SIPP----F---------CEMCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------M----N

PF00067 // ENSGT00880000137861_0_Domain_2 (350, 1252)

-PIVVLHGYEA
V---KEALIDNGEE-FSG--RGNSP---I-SQRI-TKGL-----------G----IISS-
-NG--K-RWKEIRRFSLTTLRNF--GMGKRSIE--DRVQEEAHCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSVV
FQKRFDYKDQ-NF-LTLMKRFNENFRILNS-----------PWI-----QV----C----
-NNFPL-LI----DCFP-GT--HNELLK-NVGLTKSYIME---KVKEHQ----ASLDVNN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFNIENLV-GTVADLFV
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RRPCMQDRSHMPYTDAVVHEIQRYIDLVPTG-VP
HAVT-TD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-IMT--LLTSV-LHDD-KEFPNPKIFD-----P
GHFLDKNGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTTILQ-NFNLKS
VDDL---KNLNTTA-VTKGI-V-------SLPP----S---------YQICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPIL--VLVLT-------------------LSC-
-LFLLSLW--RQSS-ERGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------DIC--Q-SF----T--NL-SKVYGP-VYTLYLGR----K-PTVVLHGYEA
V---KEALVDHGEE-FAG--RGRFP---V-FDKA-TNGM-----------G----LAFS-
-KG--N-VWKNTRRFSLMTLRNL--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FQDRFDYKDR-DF-LNLMEKLNEITKILSS-----------PWL-----QI----C----
-NTYPA-LL----DYCP-GS--HKQFFK-NYASIKNFLLE---KIKEHE----ESLDVTI
-PRDFID-----------YFLINGG-Q--------EDGNQP-LQNRLEHLA-ITVTDLFS
AGT-ETTS-TTLRYAILLLLKYPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---HVIGKH-RSPCMQDRSRMPYTDAMIHEVQRFIDLIPNS-LP
HEVT-SD--IKFRNYFI--PK---------------------------------------
-----------------------GT-T-VIT--SLSSV-LHDS-TEFPNPEKFD-----P
GHFLDENGKFK--KSDYFIPFST-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTSILQ-NFNLKP
LVHP---KDIDVTP-MLIGL-A-------SVPP----A---------FQLCFIPS-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPTV--VLVLC-------------------LSC-
-LLLFSLW--KQSH-GKGNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPILGNI-------LQI-----DF-K-----
----------DIS--K-SL----T--EL-SKVYGP-VFTVYLGM----K-PTVVLHGYEA
V---KEALIDLGEE-FSG--RDSFP---L-NAKV-NKGL----------G-----VVFS-
-NG--K-TWKDTRRFSLMTLRNF--GMGKRSIE--ERVQEEARCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGAA----PCNVICSVI
FQNRFEYRDS-EF-LNLMGKFNENFRNANS-----------LTI-----QI----C----
-NMFPI-LL----DLLP-GK--HKKSIK-NTTYIKNYALE---KVKEHQ----ESLDINN
-PGTSID-----------VSLIR-E-Q--------EKHNPQ-SEFTIDNLL-VTVFDLFA
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRH-RSPCMQDRSRMPYTDAVVHEIQRFIDLIPII-VP
HTTT-CD--VKFRNYLI--PQ---------------------------------------
-----------------------GT-P-IVP--SLSSV-LHDK-KEFPNPEEFD-----P
GHFLDKSGNFK--RSDYFMPFST-GK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLFLTSILQ-NFTLKP
HVDV---KEIDTSP-LVSGL-G-------RVPR----F---------YKLSFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELGG-A---FTI--FLALS-------------------LSC-
-LLILIAW--KRNS-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PIPFLGNV-------LQV-----RT-D-----
----------ATF--Q-SF----MK---LREKYGP-IFTVYMGP----R-PVVVLCGHEA
V---KEALVDRADE-FSG--RGELA---S-IERN-FQGHG---------------VALA-
-NG--E-RWRILRRFSLTILRDF--GMGKRSIE--ERIQEEAGFLLEE------LR-KTK
----GS-P----I------------------------E-PTFFLSRT----VSNVISSVV
FGSRFDYEDK-QF-LKLLQMINESFIEMST-----------PWA-----Q-L---Y----
-DMYSG-IM----QYLP-GR--HNRIYY-LIEELKDFIAS---RVKINE----ASLDPQN
-PRDFID-----------CFLIKMHQ---------DTNNPH-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGLLLMMKHPEVE----------------------------------
------------------------------------------------------------
-------AK-IH----E---E---------------------------------------
--------------ID---QVIGPH-RIPSVDDRAKMPYTDAVIHEIQRLTDIVPMG-VP
HNVI-RD--THFRGYLL--PK---------------------------------------
-----------------------GT-D-VFP--LLGSV-LKDP-KYFRYPDAFY-----P
QHFLDEQGRFK--KNEAFVPFSS-GK----------------------------------
--------------------------RI-CL--GEAMAR--MELFLYFTSILQ-NFSLHS
LVPP---ADIDITP-RVSGF-G-------NIPP----T---------YELCLKAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MGLTVL------L--VLALL--------------------SGL
LLLMF--R--GHPK-THGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPFLGNL-------LQM-----DR-K-----
----------GLL--K-SF----L--Q-FREKYGD-VFTVYLGP----R-PVVMLCGPEA
I---REALVDQAEA-FSG--RGTTA---T-MEPV-FQGY----------G-----VVFA-
-NG--E-RWKALRRFSLTTMRDF--GMGKRSVE--ERIQEEAQCMLEE------LR-KSQ
----GG-L----V------------------------D-PIFLFHSV----TANIICSIV
FGKRFDYKDH-QF-LRLLDLFYKTFSLGSS-----------FSS-----QV----L----
-ELFPS-IL----KHFP-GP--HREIYK-NMQEINTFIGH---SVEEHR----DTLDPSS
-PRDFID-----------TFLLRMDK---------DKADQH-TEFHHKNLI-LTSLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLFL
LKYPHIT-ERVQKEIE---QVIGSH-RPPALDDRTKMPYTEAVICEMQRFADLLPIG-VP
HVVT-KD--TSFRGFVL--PK---------------------------------------
-----------------------GT-E-VYP--ILSTA-LHDP-RHFEKPDTFN-----P
DHFLDAKGALR--KSEAFIPFSM-------------------------------------
------------------------GKRI-CL--GEGIAR--AELFLFFTTILQ-NFSIAS
PVPP---EDIDFTP-QEVAFG--------RIPP----V---------YQMSFLPRKMD--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLALF--------------------VGF
LLFMV--R--GHPK-AHGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--N-SF----I--Q-LREKYGD-VFTVHLGP----R-PVVMLCGTEA
I---REALVDQAEA-FSG--RGTIA---V-IEPI-VQGY----------G-----LVFS-
-NG--E-CWKTLRRFSLATMRDL--GMGKRSVE--ERMQEEARCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFIFQSI----TANIICSIV
FGERFDYEDR-QF-LHLLNLIYQTISLLSS-----------FSS-----QV----F----
-ELYSG-FL----KFFP-GT--HRQIYK-MMQEILDYIGH---SVEKHR----ETLDPNN
-PRDYID-----------TYLIHMEK---------EKSNQH-TEFHHQNLM-ISVLTLFF
AGT-ETSS-TTLRF----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLL
LKYPHVA-EKVQKEID---QVIGSH-RPPTLDDRTKMPYTEAVLREIQRFADILPIG-VP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------NT-E-VYT--ILSAA-LHDP-RYFEQPDAFN-----P
DHFLDANGDLK--KNEAFMPFSS-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PVAP---KDIDLRP-KESGLT--------RVAP----T---------YQIQFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPTIV------L--FLTLF--------------------LAF
LVLLV--R--GHSK-AHGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQM-----DR-G-----
----------GLL--N-SF----R--Q-FREKYGD-VFTLYLGS----K-PVVMLYGTEA
I---REALVDQAEA-FSG--RITIA---V-LKPI-FMDY----------G-----VIFA-
-NG--E-RWKALRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PKFLFQCI----TANIICSIV
FGERFDYKDG-QF-LRLLDLFYQTFSIISS-----------LST-----QM----F----
-EFFSG-FL----KYFP-GS--HVQVCK-NLQEILDYIGH---SVEKHR----LNLDPSN
-PRDFID-----------TYLLRMEK---------EKSIPH-TEFHHKNLV-ITVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVIGSN-RLPTLDDRTKMPYTEAVIHEIQRFSDLIPIG-VP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------DT-E-VYP--ILSSA-LHDP-QHFEQPDTFN-----P
DHFLDANGALK--KNEAFMPFSI-DIFRQ-------------------------------
-----------------------KKERI-CL--GEGIAR--NELFLFFTTLLQ-NFSLSS
PMAP---KDIDLSP-KENGFG--------RVPP----D---------YQICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------IITLTATMLASGML----LV--ALLAC-------------------LS--
VMVLMSVW--RQR-KLWGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPFIGNY-------LQL-----NTQQ-----
-----------MY--N-S-------LMKLSERYGL-VFTVHLGS----R-RVVVLCGYDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIETFRG-------TR
----GT-F----I------------------------D-PTYFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------ATG--Q---L----Y----
-DMFYS-VM----KYLP-GP--QQQAFK-ELQGLEDFITK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMRE---------EKKNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVQ----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKLHEEID---QVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFADMIPMG-VA
RRVT-KD--TKFRNFFI--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDT-KFFSNPQDFN-----P
RHFLDEKGQFK--KNDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFVFLTTILQ-NFCFKS
PQSP---KDIDVSP-KHVGFA--------TIPR----T---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------MKLRGF
KKMK-------------------------------KNKDRS---HSQ-----VNF-----
--VEYPPQL----FFLHFLI

PF00067 // ENSGT00880000137861_0_Domain_1 (201, 251)

QGTM-IFPAL--KSVLCDIREFPNPEQFNPGHFLDKNGA-
-FKKSDFF--

ENSGT00880000137861_0_Linker_1_2 (251, 261)

MQSP-GSGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPV---AFPLIGNM-------LQL-----RK-K-----
----------SLP--L-HI----E---ELSRTYGP-IFTIYLGS----E-RVVVLHGYEI
V---KEALVGLGDE-FSR--RGRMP---L-FETA-TKGS----------G-----IAFT-
-NG--E-QWKQLRRFVLMTLKDF--GMGKKSIE--ERIQEETRFLVER------LR-NTH
----GR-P----L------------------------N-PRLLLTHV----FSNIICSIV
FGDRFDYEDK-NF-VTLISLILENSKLQQS-----------PWA-----AL----Y----
-NFFPT-LM----DYIP-GP--HHGVFK-NFEECRIFVQE---RVNMHK----ESLDPTC
-PRDFID-----------AFLIKME-E--------EQKNSD-SVFTEESLV-RSTVDLFV
TGT-GTSS-TTLYFGLLVLLKFPEIE----------------------------------
------------------------------------------------------------
-------AK-VH----E---E---------------------------------------
--------------ID---SVIGRS-RSPSMADRSQMPYTDAVLHEIQRFLAIVPLG-IP
HAVT-KD--VHLKQYVI--PK---------------------------------------
-----------------------HT-T-IFA--ALKSV-LYDS-REFPNPEQFN-----P
GHFLDENGAFK--KSDFFMPFST-GK----------------------------------
--------------------------RM-CL--GESLAR--MELFLALTAILQ-NFTLNP
VVEP---RDVDITP-VTTFV-G-------NLPK----P---------YELRVLCR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAVLGI----ET---LFLVC-------------------SFTF
LVF-LF-----SRRQRHARL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPLLGNV-------LQL-----DF-S-----
----------KQV--K-EF----V---KLGSQYGP-VSMVYLGP----Y-PVLVLNGYDV
V---KEAFVDNGEV-FSN--RGKNA---F-IEMI-FKG----------RG-----VAFS-
-NG--E-RWRQMRRFSLSTLRDF--GMGKRRVE--ERVQEEACALVEE------FK-KTK
----GT-P----F------------------------N-STYLMTLA----VSNVICSVV
FGERFDYQNE-TF-LSVLALLKDTFKIITS-----------PWT-----QL----F----
-SFAPG-LL----KHLP-GP--HKKAAE-NLDRLKTFVTE---FVASHE----ETLEENF
-PRDYID-----------CFLIKMR-Q--------EKDNVN-TEFDYENLF-VTLMNLFF
AGT-ETTS-ITLQYGMLILLKYPDIQ----------------------------------
------------------------------------------------------------
-------KK-IH----E---E---------------------------------------
--------------ID---SVIGFN-RCPSMEDRPKMPYTDATIHEIQRFADIVPMG-VP
RSTN-KD--TTLRGYDI--PK---------------------------------------
-----------------------GT-T-VFP--MLTCI-LKDP-RYFKDPESFN-----P
CHFLDEKGCLK--KTDAFIPFSI-GK----------------------------------
--------------------------RV-CL--GEGLAR--MEIFLFLTSILQ-RFELKC
HMDP---KDIDISP-VPSKS-A-------YMPR----P---------YELYITPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVF------L--FLALL--------------------TGL
LLLLV--R--RQPK-AHGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--K-SF----L--K-LREKYGD-VFTVYLGR----R-PVVMLCGVDA
I---REALVDQAEA-FSG--RGKIA---I-VDPI-FQGH----------G-----VVFA-
-NG--D-RWKVLRRFSLTTMRDF--GMGKRSVE--ERIQEEAQCLVQE------LR-KSK
----GA-L----V------------------------D-PIFFFHSI----TANIICSIV
FGKRFDYQDK-EF-LKLLHLFYESFSLVSS-----------LFS-----QL----F----
-ELFSD-FL----KYLP-GA--HRQIHK-NLQEISAFIGH---SVEKHR----EALDPSS
-PQDLID-----------TYLLHMEK---------EKSNPH-SEFNHQNLI-LNTLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-ERVYKEIE---QVIGPH-RPPALDDRAKMPYTDAVIHEIQRIADLLPIS-LP
HMAT-QH--TSLRGYTI--PK---------------------------------------
-----------------------GT-E-VFP--ILSTA-LHDP-HYFEKPDTFN-----P
DRFLDANGALK--KNESFIPFSL-------------------------------------
------------------------GKRI-CL--GEGIAR--TELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-QEIGVG--------KIPP----T---------YQIRFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------EK-ASMDLVV--VLVLS-------------------LSF-
-LLLLSLW--KQSH-GRRRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PFPILGNI-------LQL-----DV-K-----
----------DIS--T-SL----T--NL-SKVYGP-VFTVYLGM----E-PTVVMHGYEA
V---KEALVDLGEE-FSG--RTNFP---V-TAKL-NQAS----------GR----VIFS-
-NG--K-RWKEMRRFSLMTLRNF--GMGKRSIE--ERVQEEARCLVEE------LR-KTS
----AS-P----C------------------------D-PTFILACA----PSNVICSVI
FQNRFDYRDP-KF-LNLMGKFNENFKILNS-----------PWL-----QF----C----
-NIFPI-LM----DYLP-GS--HNKVIK-NFAEIRGYILE---KIKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------ENNNEQ-SEFTTESLI-GTITDLFV
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRH-RSPCMQDRSRMPYTDATVHEIQRYIDLIPNN-VP
RATT-CN--IKFRNYLI--PK---------------------------------------
-----------------------GT-S-IIA--SLTSV-LYDD-KEFSNPQTFD-----P
GHFLDDRGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTAILQ-KFTLKS
LVDP---RDVDITP-VFKGF-G-------HVPP----L---------YQLSFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLVSGML----LV--VVLTC-------------------LS--
VMIIMSVW--RQR-RLLRKM

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1249)

PPGPT---PLPFIGNF-------LEL-----DTEK-----
-----------FY--D-C-------LSKMRERYGP-VFTIHLGP----R-PAVMLWGYDA
V---KEALIDQAEE-LSD--RGEQAFFDW----F-FKG--------------YGV-VFS-
-SG--E-RAKQLRRFSIATLRDF--GFGKRGIE--ERTIEETSFLIQALRD-------TN
----GA-T----I------------------------D-PTFYMSRT----VSNVISSIV
FGNRFEYDDK-EF-LSLLGMIMRSFQFMST-----------STG-----QL----F----
-EMFYS-VM----KHLP-GC--QHQAYK-EMQGLEDFIAR---KVEENQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EKKNPR-TQFHMRNLL-MTTLNLFF
AGT-ETVS-TTTRYGFLLLMKYPHIA----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKMHEEID---QVIGRN-RQPKYEDHLKMPYTEAVIYEIQRFVDVVPLG-LP
RSTT-KD--IKFRDFLI--PKGT-------------------------------------
--------------------------D-VFP--VLSSV-LKDP-KFFSNPNDFN-----P
QHFLDDKGQFK--KSNAFMPFSV-------------------------------------
------------------------GKRY-CF--GESLAK--MELFIFFTTIMQ-NFCFKS
PQAP---QDIDVTP-QYFSFA--------AIPP----K---------FTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (416, 1252)

LLFS-
-SG--E-RWKVLRRFSLMTMKNF--GMGKRSLE--ERVQEEAQCLVEE------LR-QMG
----AQ-P----F------------------------D-PTFILACA----PCNVICSIL
FNERFHYKNK-TL-LTLMDLLNKNFHQVNS-----------VWC-----QM----Y----
-NLWPT-LM----KHIP-GK--HKEFLR-RLGDVKNFILE---KVEEHR----ESLDPAN
-PRDYID-----------CFLSKIE-E--------EKHNLK-SEFDLENLA-ICGSNLFT
AGT-ETTS-ITLRFGILLLVKYPEVQ----------------------------------
------------------------------------------------------------
-------AK-VH----E---E---------------------------------------
--------------ID---CVIGHH-HAPSMKDKVKMPYTDAVLHEIQRYITLLPSS-LP
HAVV-KD--TKFRHYVI--PK---------------------------------------
-----------------------GT-A-VFP--LLSSI-LLDH-KEFPNPKTFD-----P
GHFLDKNGCFK--KTDYFVPFSL-GK----------------------------------
--------------------------RS-CV--GESLAR--MELFLFFTTILQ-KFSLKS
-LEP---RDLEIKP-VATGL-I-------NLPP----P---------YKLCLIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPLGAT-T---V--FLVIC-------------------VSC-
-LLFFSVR--RKTS-GSGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPV---AFPLIGNA-------LQL-----NL-R-----
----------NMP--D-SV----H---KISAKYGP-VFTLSFGS----E-RIVILCGHKA
V---KEALIDQGED-FSG--RGTFP---L-ADVL-AKGT----------G-----IIFS-
-NG--E-QWKQLRRFALTTLRNF--GMGKKSIE--MRIQEEARFLVER------LR-NTH
----GQ-P----F------------------------D-PTICLTHT----VSNVICSIV
FGDRFDYEDQ-KF-LTLINLVEENNDLVGS-----------ALV-----QV----Y----
-NFFPT-FM----SYLP-GP--HKKILK-NSQEFNSFVRE---RIKMHK----ESLDPSC
-PRDFID-----------AFLIKME-E--------ERQNGQ-SVFNTDNLV-RSTIDLFL
AGT-GTTS-TTLRHGLLLLLKYPDVE----------------------------------
------------------------------------------------------------
-------EK-VH----E---E---------------------------------------
--------------ID---RVIGRN-RSPCMVDRSQMPYTDAVIHEIQRFVNLVPFS-VP
HAVT-KD--VRFREYVI--PK---------------------------------------
-----------------------GT-T-VIL--SLQSI-LHDG-KEFPNPEQFN-----P
GHFLDENGAFK--KSDFFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLVLTVILQNNFTLKP
LIDP---KDIDVTS-IPNFV-I-------LAPK----P---------YRLCVLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMALLSVW--RQR-KIWGKLPPGPT---PLPFLGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISERYGP-VFTVHLGP----R-RVVVLCGYDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIEAFRA-------TR
----GA-L----V------------------------D-PTFFLSQA----FCNVISTVA
FGDRFHYENK-EL-LSLLGMMKGSLEFTAT-----------SAG--Q---L----Y----
-EMFYS-------------------AFK-ELQGLEDFIAK---KEVQPS----SHCL---
-----------------------PLQ--------

PF00067 // ENSGT00880000137861_0_Domain_2 (695, 1251)

-EKKNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDMIPMG-LA
RRVT-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPRDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTILQ-NFRFQS
PQSP---EDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MALGFV----GTI--LLTAC-------------------V-TI
LLF-LFKW--RGKIK-IKNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PVPLLGNI-------PQI-----NT-T-----
----------ELP--T-SL----L---ELSKTYGP-VYTLHLGS----Y-RSVMLIGYDA
V---KEALIDRSEV-FSD--RGIMD---F-TELI-FKN----------NG-----VLMT-
-NG--E-RWKTMRRFTLMTLRNF--GMGKRSIE--ERIQEESQSLAEA------FE-KNK
G---GQ-P----F------------------------D-PMYLLVLA----VSNIICSII
FGERFDYEDQ-KF-LTLLKYLREIIRLSNT-----------FIG-----QL----L----
-NFFPN-VL----QYIP-GP--HQNIFT-YFDKLKEFVRE---EANAHK----DTLDKNC
-PRDFID-----------CFLMRME-E--------ESMNPN-SEFHNENLN-QVIFDLFI
AGT-ETTS-VTLRYAFLILLKYPEIQ----------------------------------
------------------------------------------------------------
-------EK-IH----K---E---------------------------------------
--------------ID---QVIGQD-RCPSVVDRSKMPYTEAVIHEVQRFADIVPAG-LA
HAAS-KD--TTFRGYNI--PK---------------------------------------
-----------------------GT-L-IFP--VLTSV-LKDP-KFFKNPYQFD-----P
GHFLDNEGNFR--KNDAFMPFSG-GK----------------------------------
--------------------------RV-CA--GEGLAR--MELFIFLTTILQ-KFILKP
TVDI---KDIEITP-EPKTN-G-------SQPR----S---------YKMFVVPRC----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MEFFSGTKMDFSGA----ITI--LLAMA-------------------VSCL
LFLNF-----SS-KKKYRTL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPFIGNI-------HQV-----DI-K-----
----------ELI--K-SL----R---ELSKTYGP-MYTFYLGS----R-PCVVLSGYQV
L---KEALIDKAEE-FSG--RGDFP---A-VQMW-SKG----------NG-----IVYG-
-TG--E-CWRQLRRFAITTFKSF--GMGKRSIE--ERIKEEAQFLIAE------FH-KTE
----GK-P----F------------------------D-PTFCLSCA----GSNIICTLV
FGDRFEYTDK-KF-LTLLDLINNNWKLMSS-----------TWG-----QM----L----
-FTFPK-IM----RHIP-GP--HRQIYK-NYLKLAEFVGE---RLEMNK----QTLDPNS
-PRDFID-----------CFLIKIQ-Q--------EKNNPN-TYFNEDTMS-KTTVNLFF
AGT-ETVS-STLKYGLRILLRHPEVE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPN-RSPCMEDRIRMPYTDAVIHEIQRYADIVPMG-VP
HTVT-RD--IDFRGYTL--PK---------------------------------------
-----------------------DL-N-IIP--LLCTS-QFDP-TQFKNPNNFD-----P
THFLDKNGRFK--RNDAFMAFSA-GK----------------------------------
--------------------------RV-CL--GENLAL--MELFIFLTTILQ-NFKLKP
LMDP---KDIDITP-ESTGL-G-------SIPR----P---------YKFCLLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
---------------------------MVKKREIWKGLETGRGGTWEPQT------LRGR
ESSGKDPAELP-APPRLCLG-------------------LAGACTAP----------SS-
--SCWACPGPALRPAQPMALPMA----LLS--F--FL-------------------LLLL
VGLA--LW--SRAKDTGADL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1198)

PPGPP---PLPGLGNL-------LQL-----PG-A-----
----------PLL--Q-AL----L---RLKDQYGP-VFTVRLGR----T-PVVVLCGAQA
V---REAPVNQADA-FGG--RADLA---I-SEKT-HRGY----------G-----IAFS-
-QG--E-RWRTLRRFALTTLRDL--GLGRRSLE--ERIQESKFYVKFK-----TSR-ELQ
----GT-P----L------------------------D-PTFPIRRS----TANIICSVV
SGRRLHFQDE-DF-KAFLGLLAEHLKQMDT-----------CWV-----QA----Y----
-GLFPA-LL----RHLP-GP--HNRLFE-VFEKQKEFVAQ---VVKEHQ----VSLDPAQ
-PRDFID-----------AFLISMQQ---------EQGDP-HTEFNQENLL-NSALDIFF
AGM-ETTS-TTLRYGLLILLKFPQGA----------------------------------
------------------------------------------------------------
-------EL-IQ----Q---E---------------------------------------
--------------ID---QVVGPE-RRPCLGDRPGMPYTEAALHEIQRLVDIMPLG-VP
RAVT-RD--TEFRGYHI--PKGT-------------------------------------
--------------------------T-VFP--LLHSV-LHDP-DQFQDPSCFQ-----P
QRFLDAGGAFR--RSPAFLPFSA-------------------------------------
------------------------GRRA-CP--GEALAR--AELFLYLTWLLQR-FSPTS
PLPP---SALPAAP-GQWLREA-------ATPF----P---------AHPAAATALQTQG
HLPP--------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELGG-A---FTI--FLALC-------------------FSC-
-LLILIAW--KRVQ-KPGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PIPFLGNL-------LQV-----RT-D-----
----------ATF--Q-SF----LK---LREKYGP-VFTVYMGP----R-PVVILCGHEA
V---KEALVDRADE-FSG--RGELA---S-VERN-FQGHG---------------VALA-
-NG--E-RWRILRRFSLTILRDF--GMGKRSIE--ERIQEEAGYLLEE------FR-KTK
----GA-P----I------------------------D-PTFFLSRT----VSNVISSVV
FGSRFDYEDK-QF-LSLLRMINESFIEMST-----------PWA-----Q-L---Y----
-DMYSG-VM----QYLP-GR--HNRIYY-LIEELKDFIAA---RVKVNE----ASLDPQN
-PRDFID-----------CFLIKMHQ---------DKNNPH-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGFLLIMKHPEVQ----------------------------------
------------------------------------------------------------
-------TK-IY----E---E---------------------------------------
--------------IN---QVIGPH-RIPSVDDRVKMPFTDAVIHEIQRLTDIVPMG-VP
HNVI-RD--THFRGYLL--PK---------------------------------------
-----------------------GT-D-VFP--LLGSV-LKDP-KYFCHPDDFY-----P
QHFLDEQGRFK--KNEAFVPFSS-GK----------------------------------
--------------------------RI-CL--GEAMAR--MELFLYFTSILQ-NFSLHP
LVPP---VNIDITP-KISGF-G-------NIPP----T---------YELCLIAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSF-
-VLLFSLW--RQSS-GRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1103)

PPGPT---PLPIIGNM-------LQI-----DV-K-----
----------DIC--K-SF----S--NF-SKVYGP-VFTVYFGM----N-PVVVLHGYEA
V---KEALIDNAEE-FSG--RGLLP---I-SERT-TKGL-----------G----IIFS-
-NG--K-RWKETRRFSLTTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSIV
FQKRFDYKDE-NF-LTLMKRFTVNFRILTS-----------PWI-----QV----C----
-NNFPL-LI----DCFP-GI--HNKLLK-NVALTKSYIRE---KVKEHQ----ASLDINN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFTIENLV-GTVADLFI
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSHMPYTDAVVHEIQRYIDLVPTG-VP
HAVT-TD--IKFRNYLI--PK---------------------------------------
-----------------------GT-M-IMT--LLNSV-LQDD-KEFPNPKIFD-----P
GHFLDENGNLK--KSDYFMPFSA-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MKTTS----
----QKTRVKQGRV-VHTCNLSTLA---G-QACC-LFPP----------G----

PF00067 // ENSGT00880000137861_0_Domain_2 (415, 1252)

-IAFS-
-NG--E-RWKVLRRFSLQILRNF--GMGNRSME--ERILEEGSFLLEE------LR-KTE
----GQ-P----F------------------------N-PLFMLSRS----VSNIICSVV
FGSRFHYDDE-RL-LTIIRLINDNFQIMST-----------PWG-----EL----Y----
-NIFPS-LL----DWLP-GP--HLRMFK-NFRGMKELIAH---SVREHQ----ASLDPDS
-PRDFID-----------CFLTKMA-Q--------EKKDPL-SHFCMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFLILMKYPKVQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---RVVGRS-RLPSLNDRAAMPYTDAVIHEVQRFADIIPMN-LP
HRVT-RD--TIFRGFLL--PK---------------------------------------
-----------------------GT-D-VIT--LLNTV-HSDP-SQFVKPQEFN-----P
EHFLDANQSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CM--GESLAR--MELFLFFTAILQ-SFTLQP
LVAP---EDIDLTP-LSTGL-G-------KVPR----P---------FEMCMSLR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFI--VLVIC-------------------LSC-
-LILLFLW--NQSY-VKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIVGNI-------LQI-----NT-K-----
----------NIS--K-SR----S--KL-AEDYGP-VFTVYFGM----K-PTVVLHGYEA
V---KEALVDQSEE-FSG--RGSMP---V-FDKV-SQGL-----------G----IVFS-
-NG--E-RWKQTQRFSLTVLRNM--GMGKNTIE--DRIQEEALCLVEA------LR-KTN
----AS-P----C------------------------D-PTLLLGCA----PCNVICSVV
FHCCFEYSDE-KL-LTLLNYLDENMKIAST-----------AWI-----AL----Y----
-NALPF-LI----HYLP-GS--HNALFN-NIAGQQKFILE---KIKEHQ----ESLDLNN
-PRDFID-----------YFLIKME-KE---L---EKHNKQ-SEFTMDNLI-TTIWDLFS
TGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------GK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSRMPYTDAVVHEIQRYIDLVPNN-VP
HATT-RD--VKFREYLI--PK---------------------------------------
-----------------------GT-A-ILL--SLTSV-LHDD-KEFPNPEQFD-----P
GHFLDASGNFK--KSDYFMAFS-AGKQT--------------------------------
--------------------SFLSVNRV-CV--GEGLAR--MELFLLLTNILQ-HFTLKP
LVDP---KDIDTTP-PASGI-T-------SVPP----F---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------H-----
----------LAP--C-LS----L---

PF00067 // ENSGT00880000137861_0_Domain_2 (328, 1252)

QLAERYGP-VFTLYLGS----Q-RTVVLHGYKA
V---KEALLDHKND-LSG--RGEIFAFQL----HKDRG-----------------ITFN-
-NG--P-GWKDTRRLSLTMLRDF--GMGKRGNE--ERIQREIPFLLEA------LR-GTR
----GQ-P----F------------------------D-PTFLLGFA----PCNVIADIL
FRKHFDYTDE-TA-LRIQRLFNENFRLLST-----------GWL-----QL----Y----
-NIFPS-YL----HYLP-GS--HWKMLR-NVSEIKDYTSA---RVKEHQ----LSLDAGC
-PRDFTD-----------CLLLELQK---------ERYSSE-PWFTLDNIA-VTVADLFF
AGT-ETTS-TTLRYGLLVLMKYPEVE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RIPAIKDRLEMPYMDAVVHEIQRFIDLLPSN-LP
HEAN-RD--TVFRGYII--PK---------------------------------------
-----------------------GT-V-VIP--TLDSL-LFDK-QEFPDPETFK-----P
EHFLNENGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLFLTAILQ-HFNLKS
LVDP---KDIDLSP-IAIGF-A-------KIPP----H---------YKLCLTPRSG---
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLLLGAA-S---V--VLLVC-------------------VAC-
-LLSIVQW--RKRT-GKGKM

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PEGPT---PLPIVGNI-------LEV-----KP-K-----
----------NLA--K-TL----E---KLAEKYGP-VFSVQLGS----T-PVVVLSGYEA
V---KEALIDRADE-FAA--RGHMP---I-GDRA-NKGL----------G-----IIFS-
-NN--E-GWLHVRRFALSTLRNF--GMGKRSIE--ERIQEEAEHLLEE------IT-KTK
----RL-P----F------------------------D-PTFKLSCA----VSNVICSIV
FGKRYDYKDK-KF-LSLMNNMNNTFEMMNS-----------RWG-----QL----Y----
-QMFSY-VL----DYLP-GP--HNNIFK-EIDAVKAFVAE---EVKLHQ----ASLDPSA
-PQDFID-----------CFLSKMQ-E--------EKDNPK-SHFHMTNLI-TSTFDLFI
AGT-ETTS-TTTRYGLLLLLKYPKIQ----------------------------------
------------------------------------------------------------
-------EK-VQ----E---E---------------------------------------
--------------ID---RVVGRS-RRPCVADRTQMPYTDAVVHEIQRFITLIPTS-LP
HAVT-KD--IHFRDYII--PK---------------------------------------
-----------------------GT-T-VMP--LLSTA-LYDS-KEFPNPTEFN-----P
GHFLNQNGTFR--KSDFFIPFSA-GK----------------------------------
--------------------------RI-CP--GEGLAR--MEIFLLLTAILQ-NFTLKP
VISP---EELSITP-TLSGT-G-------NVPP----Y---------YQLCAIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MDWALEINGL----PIL--LLIAA-------------------LLLL
-LA----R--KVGKKVKGCL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPK---PLPILGNL-------LQL-----KS-R-----
----------EIH--K-PL----L---EFNKKYGP-VYTLYMGS----M-PAVVLCGYEA
V---KEALVDNAEK-FSG--RAEVP---I-VNLT-TQG----------YG-----IAFS-
-NG--E-RWKELRRFSLTTLRNF--GMGKRSIE--ERIQEEIHFLLEA------FH-ETQ
----GS-F----F------------------------S-PAFIIRRS----VSNVICSVV
FGKRFDYTDQ-KL-QILLDLIAENLRRVDN-----------IWV-----QV----Y----
-NFIPK-LL----NILP-GP--HHKLTE-NYKAQLRYVEE---IVQEHG----KTLDPSA
-PQDYID-----------AFLLKME-Q--------ERKKAH-TEYNVQNLL-SCSLDIFF
AGQ-ESTS-STLGYGLLILMKYPHIK----------------------------------
------------------------------------------------------------
-------EK-VQ----A---E---------------------------------------
--------------IE---SVIGRS-RRPCMDDRAKMPYTEAVIHEIMRFIDFFPLG-VP
HSVT-ED--TLYRGYVI--PK---------------------------------------
-----------------------GT-T-IFP--FLHSV-LFDP-SMFERPQEFY-----P
GHFLNQDGSFR--KNEGFMAFSA-GK----------------------------------
--------------------------RA-CP--GKSLAR--VEIFLYLTSILQ-QFDPQP
ALSP---KDIDLSP-EYSGF-G-------KMAP----S---------FQLKLVPH-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDAVL--VLVLI-------------------LSS-
-LLLLSFW--RQNS-ERRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------DIS--K-SI----K--KF-SEVYGP-VFTLYFGL----K-PTVVVYGYEV
V---KEVLDG--EE-FSG--RGVFP---I-VTKV-NNDL----------G-----VIFS-
-NG--T-KWKELRRFSLMTLRNF--GMGKRSIE--DRIQEEASCLVEE------LR-KTN
----GS-L----C------------------------D-PTFILSCA----PSNVICSVI
FHNRFDYKDE-NF-LNLMEKFNENFKILNS-----------PWM-----QV----C----
-NAIPA-FI----DYLP-GS--HNKVIK-NFAEIKSYILR---RVKEHQ----ETLDMDN
-PRDFID-----------CFLIKIE-Q--------EKHNPC-TEFTIQSLV-ATVTDVFV
AGS-ETTS-TTLRYGLLLLLKHTEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RRPCMQDRTRMPYTDAMVHEIQRYINLIPNN-VP
HAAT-CN--VRFRNYVI--PK---------------------------------------
-----------------------GT-D-LIT--SLTSV-LHDD-KEFPNPEVFD-----P
GHFLDEHGNFK--RSDYFMPFSS-------------------------------------
------------------------GKRM-CV--GEALAR--MELFLLLTTIVQ-NFNLKS
FVAT---KDIDTTP-LTNTF-G-------CVPP----S---------YQLYFTPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
--------------------------------------MEGIKSHWENSRRGA----RGV
GRDD----------------------------------LRAAPTPQTSAELQGTDL--EQ
ITLLLPEAQQIPAAAFTMDSLSI----AIL--LGLLA-------------------LTSL
FLT-L------S-SRGKGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQL-----RS-Q-----
----------DML--T-SL----T---KLSKEYGC-VYTVHLGP----R-RVVVLSGYQA
V---KEALVDQGED-FSG--RGDYP---V-FFNF-TKGN----------G-----IAFS-
-NG--D-RWKVLRRFSVQILRNF--GMGKRSIE--ERILEEGSFLLAE------LR-KTE
----GK-P----F------------------------D-PTFVLSRS----VSNIICSVI
FGSRFDYDDE-RL-LTIIRLINDNFQIMSG-----------PWG-----EL----Y----
-NIFPS-LL----DWVP-GP--HRRLFQ-NYGCMKDLIAR---SVRDHQ----DSLDPNS
-PRDFID-----------CFLNKMA-Q--------EKQDPH-SHFHMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFLVLMKYPKVQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---RVVGRA-RLPALEDRAAMPYTDAVIHEVQRFADVIPMN-LP
HRVT-RD--TAFRGFLI--PK---------------------------------------
-----------------------DT-D-IIT--LLNTV-HYDP-SQFLTPQEFN-----P
EHFLDANQSFK--KNPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GESLAR--MELFLYLTAILQ-SFSLQP
LGAP---EDIDLTP-LSSGL-G-------NLPR----P---------FQLCLRPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPLGMS-T---V--LLLTC-------------------LSC-
-LLLSAIW--KSGARQKGKM

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPIIGNA-------LQL-----KT-H-----
----------HLD--Q-VL----Q---KMSEKYGP-VFTLYFGM----A-PAVVLHGYEA
I---KEALLDRGNE-FAF--RGKIH---L-MEKT-NKGK----------G-----IIFS-
-NG--E-RWKQLRRFALTTLRNF--GMGKKSIE--ERIHEEAQYLLEQ------FR-NTK
----QQ-P----F------------------------D-PHYLFSCA----TSNVICSIV
FGKRYDYKDK-KF-QAMMNLMNENFEIFNS-----------AWA-----QF----A----
-NMFPT-LM----EWIP-GP--HHQIVS-GSLRSEEFVLE---EAKEHR----ATLDPNS
-PRDFID-----------CFFIKMD-Q--------EKHNEA-SEFTMENLI-TCSLDLFG
AGT-ETTS-TTLRYGLLILQKYPEIE----------------------------------
------------------------------------------------------------
-------EK-VQ----E---E---------------------------------------
--------------ID---RVVGRS-RMPGMADRGQMPYTDAVLHEIQRFVSLVPLG-VP
HTVD-KD--TPFRGYVI--PK---------------------------------------
-----------------------GT-T-IVP--VLSSV-LHDS-KEFPNPTEFD-----P
GHFLNKDGTFR--KSDYFVPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTSILQ-NFKLKP
LTDP---KDIDIMP-RLSSL-S-------NVPQ----P---------YKFCLVPC-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDAVV--ILVLG-------------------VSC-
-LLLLSLW--RQSS-GRGKLPPGPA---PLPLVGNI-------LQI-----DV-R-----
----------DIS--K-SF----A--SF-SKVYGP-VFTLYFGT----K-PTVVVHGYEA
V---KEALDGHGEE-FSG--RGSFP---I-VEKT-NSGR----------G-----ILFS-
-NG--R-KWKEIRRFSLMTLRNF--GMGKRSLE--DRIQEEARCLVQE------LR-GTR
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FKKRFDYKDE-DF-LILMEKLNENFKILNT-----------PWM-----QV----C----
-NVFPA-FI----DYLP-GS--HKKVLK-NFAYIKSYVLE---KVKEHQ----ESLDIHN
-PRDYID-----------CFLIKMG-Q--------EKHNQN-SEFTTESLM-ATVTDLFI
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (1044, 1250)

GT-A-LIT--SLTSV-LHDD-QEFPNPEIFD-----P
GHFLDENGNFK--KSDYFMPFSI-------------------------------------
------------------------GKRM-CV--GEGLAR--MELFLFLTTILQ-SFNLKS
LVDP---KDIETIP-IANTF-G-------HVPP----L---------YKLRFISV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEASVL------L--FLTLL--------------------LGF
VVLLL--R--GHPK-AHGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQM-----DR-R-----
----------GFL--N-SF----M--R-LREKYGD-VFTVHLGP----R-TVVMLCGTEA
I---REALVDQAEA-FSG--RGTLE---L-VNPI-FKDY----------G-----VIVA-
-NG--D-HWKALRRFSLATMRNF--GMGKRTVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PKFLFKCI----TANIICSIV
FGERFDYKDR-QF-L---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-RLLDLIFQIYSLISSFSSQVFELFSGFLKYFPGAQVRISKITQEILDYIERSVEQHQKT
LDPSNPRDF-IDTYLLRMEKEKSNPHTEFQQKNLVLTVLALFFAGTETSSTTLHYGFLLM
LKYPHVA-EKVQKEIE---EVIGSH-RLPTLDDRTKMPYTDAVIHEIQRLSDVVPIG-VP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------DT-E-VYP--ILSSA-LHDP-QHFEQPDTFD-----P
DRFLDANGALK--KNEAFMPFSI-------------------------------------
------------------------GKRI-CP--GEGIAR--NELFLFFTTILQ-NFSLSS
PVDP---KDIDLSP-KESGFG--------RVPP----E---------YQICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------M----K

PF00067 // ENSGT00880000137861_0_Domain_2 (350, 1251)

-PFVVLHGYEA
V---KEALVDLGEE-FSG--RGSFP---V-SERV-NKGL-----------G----VIFS-
-NG--M-QWKEIRRFSIMTLRTF--GMGKRTIE--DRIQEEAQCLVEE------LR-KSK
----GA-P----F------------------------D-PTFILGCA----PCNVICSII
FQNRFDYKDP-TF-LNLMHRFNENFRLFSS-----------PWL-----QV----C----
-NTFPA-II----DYFP-GS--HNQVLK-NFFYIKNYVLE---KVKEHQ----ESLDKDN
-PRDFID-----------CFLNKME-Q--------EKHNPQ-SEFTLESLV-ATVTDMFG
AGT-ETTS-TTLRYGLLLLLKHVDVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRN-RSPCMKDRSQMPYTDAVVHEIQRYIDLVPTN-LP
HLVT-RD--IKFRNYFI--PK---------------------------------------
-----------------------GT-N-VIV--SLSSI-LHDD-KEFPNPEKFD-----P
GHFLDERGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CA--GEALAR--TELFLFFTTILQ-NFNLKS
LVDV---KDIDTTP-AISGF-G-------HLPP----F---------YEACFIPVQRADS
LSSHL-------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MC--T-S-------LMKISERYGP-VFTIHLGP----R-RVVVLCGHDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLIEALRG-------TC
----GA-N----I------------------------D-PTFFLSRT----VCNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EKKNPN-TEFHMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRVKMPYTEAVIHEIQRFGDVIPMS-LA
HRVI-RD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-RFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFLTTIMQ-NFRFES
PQLP---KDIDVSP-KHVGFA--------TIPP----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLVV--VLVLC-------------------LSC-
-LLLLSLW--KQSS-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPILGNI-------LQL-----DV-K-----
----------NIS--K-SL----T--NL-SKVYGP-VFTVYFGM----K-PIVVLHGYEA
V---KEALIDLGEE-FSG--RGTFP---L-AERA-NVTN-----------G----ILFS-
-NG--K-TWKEMRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GL-P----C------------------------D-PTFILGCA----PCNVICSII
FQNRFDYKDP-IF-LDLMEKLNEILRILSS-----------PWV-----QV----C----
-NSFPA-LI----DYLP-GS--HNKVIK-NAADLKSYVLE---KAMEHK----ASLDINN
-PRDYID-----------CFLIKME-Q--------EKQNQQ-LEFTLENLT-TTVFDLFG
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSHMPYTDAVVHEIQRYIDLVPSS-LP
HMVT-HD--IEFRNYII--PK---------------------------------------
-----------------------GT-G-VLV--SLSSV-LYDD-KVFPNPEMFD-----P
GHFLDESGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MEVFLFLTSILQ-KFTLKS
VVDP---KDIDTTP-TANGF-T-------SVPP----P---------YKLCFIPL-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFI--ILVIC-------------------LSC-
-LILFSLW--NGSH-ARRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PFPIVGNT-------IQL-----NT-K-----
----------DLS--K-TL----S--ML-AKEYGP-VFTVYLGM----K-PTV-------
-----EALIDRGEE-FSG--RGTLP---V-VEKV-TQGL-----------G----VVFS-
-NG--E-IWKQTRRFSLMVLRNM--GMGKKTIE--DRIQEEASCLVEA------LK-KTN
----AS-P----C------------------------D-PAFLLTCV----PCNVISSVI
FQDRFDYGDQ-KF-QNLIKYFHENFKILST-----------PWI-----QL----C----
-NTFPF--L----QYFP-GI--HNKLLK-NINAQRQFILE---KIKEHQ----ETLDINN
-PRDFID-----------YFLIRME-K--------EKHNQQ-SEFTMDNLV-ITTWDIFS
AGT-ETTS-TTLRYGLLLLLKQPEVS----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVVGRD-RSPRMQDRSRMPYTDAVIHEIQRYTDLVPIS-VP
HTVT-QD--IQFREYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDD-KEFPNPEKFD-----P
GHFLDKSGNFK--KSDYFMPFS-AGR----------------------------------
--------------------------RA-CA--GEGLAR--MELFLLLTTILQ-HFTLKP
LVDP---KDIDITP-VNKVL-G-------SVPP----S---------YELCFIPA-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--ALVLC-------------------LSC-
-LFLLSLW--RQSS-GRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PSGPT---PLPIIGNI-------LQL-----DV-K-----
----------DMS--K-SL----T--NF-SKVYGP-VFTVYFGL----K-PIVVLHGYEA
V---KEALIDHGEK-FSG--RGSFP---V-AEKV-NKGL-----------G----ILFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEALCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSVI
FHNRFDYKDP-GF-LNLMEKFNENLRILSS-----------PWI-----QV----C----
-NNFPA-LI----DYLP-GS--HNKVVK-NFAYVKSYVLE---RIKEHQ----ESLDMDN
-PRDFID-----------CFLIKME-Q--------ERHNLQ-SEFTIESLI-ATVTDMFG
AGT-ETTS-TTLRFGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---CVVGRN-RSPCMQDRSHMPYTDAVVHEIQRYIDLIPTN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-IIT--SLTSV-LHND-KEFPNPEVFD-----P
GHFLDRSGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
QVDP---KDIDITP-IANAF-G-------RVPP----L---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPLV--ILVLC-------------------LSC-
-WLLLSLW--KQNI-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PSGPH---PLPFIGNI-------LQV-----DV-K-----
----------NIG--K-SL----C--NL-SKTYGP-VFTLYFGM----K-PAVVLHGYKA
V---KEALIDLGEE-FSA--RGSFP---L-AERI-SKG-----------HG----ILFT-
-NG--K-RWKEMRRFCLMTLRNL--GMGKSDLE--SRVQEEAYYLMEE------LR-KTN
----AL-P----C------------------------D-PTFVLGCA----TCNMICSII
FQNRFDYTDQ-TL-LGFLEKFNENMKILSS-----------SWV-----QI----C----
-NSFPA-LI----DYLP-GS--HHKIFK-NFTCTHNYILE---KIKEHQ----ESLDINN
-PRDFID-----------YFLIKIK-Q--------ENHSQQ-LEFTIENLI-ATASDLFG
AGT-ETTS-TTLRYALLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-IQ----E---E---------------------------------------
--------------IG---HVIGRH-RSPCMQDRSRMPYMNAVLHEIQRYIDLIPVN-LP
HAVT-RD--IKFRNYVI--PK---------------------------------------
-----------------------GT-T-VLI--SLTSV-LRDD-KEFPNPETFD-----P
AHFLDDSGNFK--KSDYFMVFSA-GK----------------------------------
--------------------------RI-CV--GESLAR--MELFLFLTSILQ-NFTLKP
VVDI---KDLDTTP-VASGF-G-------HIPP----P---------YKICFVPL-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVL------L--FLAVL--------------------MGL
LLLLV--K--GHPN-ARGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPH---PLPLLGNL-------LQM-----DR-G-----
----------GLL--K-SF----S--R-LRERYGD-VFTVYLGR----R-PAVMLCGIEA
I---KEALVDQAED-FSG--RGKIA---I-LETV-FQGY----------G-----VFFA-
-NG--D-HWKTLRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSK
----GA-L----L------------------------D-LAFLFQCI----TANIICSIV
FGKRFDYKDE-EF-LKLLDLSYQSSSLISS-----------FSG-----QM----F----
-ELFSD-FL----QFFP-GP--HRQVYK-NLQEISAFIGR---SVDKHR----ETLDPSA
-PRDLID-----------AYLLRMEK---------EKSNPH-SEFNQKNLI-LNTLSLFF
AGT-ETTS-ITLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKHPHVA-ERVHKEIE---QVIGKH-RPPALEDRVKMPYTDAVIHEIQRFSDIAPIAGLP
HL-----------------SC---------------------------------------
-----------------------DT-E-VFP--ILNSA-LHDP-RYFEKPDAFN-----P
DHFLDANGALK--KNEAFIPFSL-------------------------------------
------------------------GKRI-CL--GEGIAK--AELFLFFTTILQ-NFSLAS
PVAP---ENIDITP-QENGLG--------KLPQ----Q---------YQIRFLPRQRG--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEFSVL------L--LLALA--------------------TGF
LLFLVS-Q--SKPK-THGHF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPFLGNL-------LQM-----DR-R-----
----------GLL--I-SF----I--K-LQEKYGD-VFTVHLGP----R-PVVILCGTDT
I---REALVNQAEA-FSG--RGTVA---V-LDPI-IQGY----------G-----VIFS-
-SG--E-RWKTLRRFSLATMRDF--GMGKRSVE--ERIKEEAQCLVEE------LK-KYK
----GA-P----L------------------------N-PTFYFQCI----VANIICSIV
FGERFDYKDH-QF-LHLLNLIYQTFWLMNS-----------LSS-----QV----F----
-ELFSA-IL----KYFP-GA--HRQISK-NLQEILDYIGH---SVEKHR----ATLDPSA
-PRDFID-----------TYLLRMEK---------EKSNHH-TEFHHQNLV-ISVLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------SFLIM
LKYPHVA-EKVQKEID---QVIGSH-RPPTLDDRTKMPYTDAVIHEIQRFTDLAPIG-LP
HRVT-KD--TLFRGYLI--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-RYFEQPNSFN-----P
EHFLDANGALK--TNEAFMPFST-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSLAS
PVAP---ENIDLIP-NKGGAT--------KTPP----L---------YQIHFLSR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MD-PSVVTAL--GLVL----------------------C-
-LLLISVW--RKGH-GKGKF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNM-------LQL-----DT-K-----
----------NVN--K-SX----X--XL-AKTYGP-VFTLYLGS----E-RTIVLHGHKA
I---KEALIDHGDV-FAG--RGSFP---V-SDTI-NKGL----------G-----IGTS-
-NG--E-RWMQMRHFFLMTLKNF--GMGKKSIE--ERVQEEAKSLVEE------LK-KTK
----GL-P----C------------------------D-PTIPLGSS----PCNVICSVV
FQKRFEYQDQ-KF-LYLMELLNENVRILSS-----------PWI-----QV----Y----
-NSFPS-LV----HYLP-GI--HHKLIK-NFT--SDFVLE---RVKEHQ----ETLDAND
-PRDFID-----------CFLMKME-Q--------EKQNPQ-SEFTIENLV-QTTLDLFG
AGT-ETTS-TTLRYGFLLLLKYPQIT----------------------------------
------------------------------------------------------------
-------RK-IH----E---E---------------------------------------
--------------TD---RVIGRN-RSPYMEDRNKMPYTNAVVHEIQRYIDLIPTN-LP
HAVT-ED--VKFRQYLI--PK---------------------------------------
-----------------------GT-I-IFP--SLHSV-LRDK-KAFPNPYQFD-----P
ENFLDKSGNFR--KSDYFTPFSL-GK----------------------------------
--------------------------RL-CL--GEGLAR--MEVFLFLTTILQ-NFTLKP
LVDP---KELDITP-LTTGL-L-------NVPP----V---------YKLSLLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLVT--FLVLT-------------------LSS-
-LILLSLW--RQRS-GRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PFPIIGNF-------LQI-----DV-K-----
----------NFN--Q-SL----T--NF-SKTYGP-VFTLYLGS----R-PIVVLHGYEA
V---KEALIDHGEE-FSG--RGNIP---M-SEKL-NNGL-----------G----ITFS-
-NG--N-SWKETRRFTLTTLRNL--GMGKRNIE--DRVREEAQCLVEE------LR-KTK
----GS-P----C------------------------D-PTFILSCA----PCNVICSII
FLDRFDYKDK-DF-LMLMEKLNENIKILSS-----------PWL-----QV----C----
-NSFPL-LI----DYCP-GS--HHKVLK-NFKYIRSYLLE---KVKEHQ----ASLDVTN
-PRDFID-----------YFLIKQK-Q--------ANHIEQ-AEYSLENLV-CTINNLFA
AGT-ETTS-TTLRYALLLLMKYPDVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVVGRH-RSPCMQDRSRMPYTDAMIHEVQRFINLVPNN-LP
HAAI-CD--IKFRNYII--PK---------------------------------------
-----------------------GT-T-VVT--SLTSV-LHDS-KEFPNPEMFD-----P
GHFLDANGNFK--KSDYFMTFSA-GK----------------------------------
--------------------------RV-CA--GEGLAR--MELFLILTTILQ-NFKLKS
LVHP---KDIDMIP-FVNGL-I-------ALPS----H---------YQLCFIPL-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ASVAF-------------------LS--
VLVLMSVW--KQR-KLSGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPFIGNF-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISQRYGP-VFTIYLGP----R-RIVVLCGQEA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGI-AFS-
-SR--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLIDSFRK-------TN
----GA-F----I------------------------D-PTFYLSRT----VSNVISSIV
FGDRFNYEDK-EF-LSLLRMMLGSFQFTAT-----------SMG--Q---L----Y----
-EMFSS-VX----KHLP-GP--QQQAFK-ELQGLEDFITK---KVEHNQ----RTLDPNS
-QRDFID-----------SFLIRMLE---------EKKNPN-TEFYMKNLV-LTTLNLFF
AGT-ETXS-TTLRYGFLLLMKHPDIEVLGYLN----------------------------
------------------------------------------------------------
------------------------------------------------------------
--PSLFFSAKVHEEID---RVIGRN-RQPKYEDRMKMPYTEAVIHEIQRFADMIPMG-LA
RRVT-KD--TKFRDFLL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-KFFSNPKDFN-----P
KHFLDDKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTNIMQ-NFHFKS
PQAP---QDIDVSP-RLVGFA--------TIPP----T---------YTMSFLSR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSML------L--LLVLL--------------------MGL
LLLLV--R--GHPK-AYGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPFLGNL-------LQM-----DR-R-----
----------GLL--K-SF----L--K-LQEKYGD-VFTVYLGP----R-PTVMLCGTEA
I---REALVDQAEA-FSG--RGKIA---V-VDQV-FQGY----------G-----VVFA-
-NG--G-RWKTLRRFSLATMKNF--GMGKRSVE--ERIQEEAQFLMEE------LR-NTK
----GA-L----Q------------------------D-PTFFFHAI----TANIICSIV
FGKRFSFRDP-EF-LRLLDLFYRSFALISS-----------FSS-----QV----F----
-QLFSD-FL----KHFP-GT--HRQVYR-NLMEINTFIGR---SVEEHR----KTLDPAS
--RDLID-----------TY-LRMDK---------EKSDPN-TEFHQQNLI-ITVLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHIT-ERVHKEID---LVIGSQ-RPPALDDRTKMPYTDAVIHEIQRFSDLLPLG-VP
HVVT-ND--THFRGYII--PK---------------------------------------
-----------------------GT-E-VYP--ILSSA-LHDP-RYFEKPDAFN-----P
DHFLDASGALK--KNEAFIPFST-------------------------------------
------------------------GKRT-CL--GEGIAR--TELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-RESGVG--------RIPP----I---------YQISFLPHHGG--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVL------L--FLALL--------------------TGL
LLLLV--Q--RHPN-AHGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPC---PLPLLGNL-------LQM-----DR-R-----
----------GLL--R-SF----L--R-FREKYGD-VFTVYLGP----R-PVVMLCGVEA
I---REALVDNAEA-FSG--RGKIA---I-TDPV-FQGY----------G-----VVFA-
-NG--N-RWKVLRRFSLTTMRDF--GMGKRSVE--ERIQEEAQCLIEE------LR-KSK
----GA-L----V------------------------D-PTFLFHSI----TANIICSIV
FGKRFHYQDQ-EF-LKILNLFYHTFSLASS-----------MFG-----QL----F----
-ELLSG-FL----KYFP-GA--HRQVYK-NLQEINAYIGH---SVEKHR----ETLDPSA
-PQDLID-----------SYLLQMEK---------EKSNPH-SEFSHRNLI-INTLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-ERIYKEIE---QVIGPH-RPPALDDRAKMPYTEAVIHEIQRFADLLPMG-VP
HIVT-QQ--TSFRGYII--PK---------------------------------------
-----------------------DM-E-VFP--LLSTA-LHDP-HYFEKPDTFN-----P
DHFLDANGALK--KNEAFIPFSL-------------------------------------
------------------------GRRI-CL--GEGIAR--NELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-QESGVG--------KIPP----T---------YQIRFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMILLSVW--RQK-KIWGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFLGNY-------LQL-----NTEQ-----
-----------IY--D-S-------LMKISERYGP-VFTVHLGP----R-QVVVLCGYDA
V---KEALVDQAEE-FSG--RGEQATFDR----L-FKG--------------YGV-AFS-
-NG--E-RTKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLLQAFRG-------TR
----GA-T----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYENK-EF-LSLLRMMLGSFQFTAT-----------ATG--Q---L----Y----
-EMFYS-VM----NHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EKKNTN-TAFCMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPRFEDRAKMPYTEAVIHEIQRFADMIPMG-LA
RRVT-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-KFFSKPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTAIMQ-NFRFKS
PQSP---EDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--ALVLC-------------------LSC-
-LFLLSLW--RQSS-GRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PSGPT---PLPIIGNI-------LQL-----DV-K-----
----------DMS--K-SL----T--NF-SKVYGP-VFTVYFGL----K-PIVVLHGYEA
V---KEALIDHGEK-FSG--RGSFP---V-AEKV-NKGL-----------G----ILFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEALCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSVI
FHNRFDYKDQ-RF-LNLMEKFNENLRILSS-----------PWI-----QV----C----
-NNFPA-LI----DYLP-GS--HNKVVK-NFAYVKSYVLE---RIKEHQ----ESLDMDN
-PRDFID-----------CFLIKME-Q--------EKHNLQ-SEFTIESLI-ATVTDMFG
AGT-ETTS-TTLRFGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---CVVGRD-RSPCMQDRSHMPYTDAVVHEIQRYIDLIPTN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-IIT--SLTSV-LHND-KEFPNPEMFD-----P
GHFLDRSGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
QVDP---KDIDITP-IANAF-G-------RVPP----L---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LS--
VMVLMSVW--RQR-KLGGKLPPGPT---PLPFIGNY-------LQL-----DTEQ-----
-----------MY--N-C-------LMKLSKRYGP-VFTVHLGT----R-RVVVLCGYDA
V---KEALVDQAEE-FSG--RGENATFDW----L-FKG--------------YGV-VFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIQAFRE-------TC
----GA-F----I------------------------D-PTFYMSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMIQGSFQFSAT-----------STG--Q---L----Y----
-EMFYS-VM----KHLP-GP--QQQAFK-ELQGLEDFVAR---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIR

PF00067 // ENSGT00880000137861_0_Domain_2 (684, 1250)

MS-----------------------------------
---------TTLRYGFLMLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKLHEEID---RVIGRN-RQPKFEDRAKMPYTEAVIHEIQRFGDMIPMG-LS
RRVI-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDT-KFFSNPEDFN-----P
QHFLDDKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTILQ-NFCFKS
PQAP---QDIDVSP-KHVGFA--------TIPR----T---------YTMSFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSIL------L--LLTLL--------------------MGL
LVLLF--R--GHPK-AHGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1238)

PPGPR---PLPFLGNL-------LQM-----NR-K-----
----------GLL--K-SV----L--Q-VRKKYGD-VFTLYLGP----R-PVVMLCGTDT
I---REALVDQAEA-FSG--RGRIA---S-IDAV-FQGQ----------S-----FNSA-
-SA--E-HWKVLRRFTLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GG-L----V------------------------D-PLFFFRPA----TANIICSIV
FGKRFDYKDQ-QF-LRLMDLIYQTFALMSS-----------FSS-----LV----F----
-ELYSS-IL----KHFP-GT--HREIYK-NFQEILTFIGH---SVEKHQ----ETLDPSA
-PRDFID-----------AYLLRMEK---------DKSDPH-TEFHHRNLV-LTSLSLFI
AGT-ETTS-TTLHY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLFL
LKYPHVT-ERVHKEIE---QVIGSH-RQPSLDDRNKMPYTEAVIYEIQRFADLSPMG-VP
RTVT-KD--THFRGFII--PK---------------------------------------
-----------------------NT-D-IYA--VLTTA-LHDP-CHFEKPDTFN-----P
DHFLDAKGALK--RSEAFMPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--VELFLFFTTILQ-NFSISG
TVAP---QGIDLTP-QEVGLG--------KVPP----T---------YELAPPACDQNRL
ATKTGL------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELGG-A---VTI--FLALC-------------------LSC-
-LLVLIAW--KRMN-KAGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PIPFLGNL-------LQV-----RT-D-----
----------ATF--Q-SF----MK---LRKKYGP-VFTVYMGP----R-PVVVLCGHEA
V---KEALVDQADE-FSG--RGELA---S-IERN-FQGHG---------------VALA-
-NG--E-RWRILRRFSLTILRDF--GMGKRSIE--ERIREEASYLLEE------FR-KTK
----GA-P----I------------------------D-PTFLLSRT----VSNVISSVV
FGSRFDYEDK-QF-LNLLRLINESFIEMST-----------PWA-----Q-L---Y----
-DMYSG-IM----QYLP-GR--HNRVYY-LIEQLKDFIAS---RVKINE----ASFDSQN
-PRDFID-----------CFLIKMHQ---------DKNNPR-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
-------AR-IH----E---E---------------------------------------
--------------IN---QVIGPH-RLPSVDDRVKMPYTDAVIHEIQRLVDIVPMG-VP
HNVI-RD--TQFRGYLL--PK---------------------------------------
-----------------------GT-D-VFP--LLGSV-LKDP-KYFRYPEAFY-----P
QHFLDEQGRFK--KNEAFVPFSS-GK----------------------------------
--------------------------RV-CL--GEAMAR--MELFLYFTSILQ-NFSPRS
LVPP---ADIDITP-KLSGF-G-------NIPP----T---------YELCLVAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MERLEIT-T---L--ALVIC-------------------VTC-
-LVFLFVW--KKSHKGLGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNL-------MQL-----NL-K-----
----------DIP--A-SL----S---KLAKQYGP-VYTLHLGS----Q-TTVVLHGYEV
V---KEALIDQGDE-FLG--RAHFP---I-IDDT-QRG----------YG-----LIFS-
-NG--D-TWKQMRRFSLMTLRNF--GMGKRSLE--ERIQEEAQFLVEE------FR-KSE
----AQ-P----F------------------------N-PAVTLSCA----TCNIICSIL
FNERFHYQDK-TL-HSLLDLLNENFNRISS-----------LWN-----QI----Y----
-NLWPK-LI----KPLP-GE--HRAFSK-RLKDVHYFVLE---KVKEHQ----KSLNHNN
-PRDYID-----------CFLSRME-Q--------EKQNPE-SQFHLENLA-TCGSNLFS
AGV-ETTT-ATLSYGFLLLMKYPEVQ----------------------------------
------------------------------------------------------------
-------AK-VH----E---E---------------------------------------
--------------ID---RVIGRT-RSPCMKDKMKLPYTEAVLHEIQRYVTLVPSN-LP
HAVV-QD--TKFRQYVI--PK---------------------------------------
-----------------------GT-T-VLP--LLSSI-LYDC-KEFPNPEKFD-----P
GHFLDKNGSFR--KTKYFVAFSI-GK----------------------------------
--------------------------RA-CV--GEGLAQ--MELFLFFTTILQ-NFVLKP
LGET---KDIETKP-IVIGL-I-------NMPP----P---------FKLCLIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MAVLGIT-----I--ALLVW-------------------VAT-
-LLVISIW--KQIY-NSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPILGNI-------FQL-----DL-K-----
----------DIP--K-SF----T---KLAKRFGP-VFTLHLGS----R-RIVVLHGYKA
V---KEVLLNHKNE-FSG--RGDIPVFQE----YKNKG-----------------IIFN-
-NG--P-TWKDVRRFSLSILRDW--GMGKQGNE--ARIQREAQFLVEE------LK-KTK
----GQ-P----F------------------------D-PTFLIGCA----PCNVIADIL
FNKRFDYNDK-KC-LRLMSLFNENFYLLST-----------PWI-----QL----Y----
-NNFAD-YL----RYLP-GS--HRKIMK-NVSEIKQYTLE---KAKEHL----QSLDINC
-ARDVTD-----------CLLIEMEK---------EKHSQE-PMYTMENVS-VTLADLFF
AGT-ETTS-TTLRYGLLILMKYPEIE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RVPAVRDRLDMPYMDAVVHEIQRFINLVPSN-LP
HEAT-RD--TVFQGYVI--PK---------------------------------------
-----------------------GT-V-VIP--TLDSL-LYDS-HEFPDPEKFK-----P
EHFLNENGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLLLSAILQ-HFNLKS
LVDP---KDIDLSP-VTVGF-G-------SIPP----Q---------FKLCVIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGML----LV--AVLTC-------------------LT--
VMVLMSVW--RQR-KLSGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKMSDRFGP-VFTVYLGP----R-RVVVLCGQEA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GLGKRGIE--ERIQEEAGFLIQALRD-------TH
----GT-F----I------------------------D-PTFYLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFYS-IM----KHLP-GP--QQQAFK-ELKGLEDFITK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EKKNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKYPNVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFADMIPMG-LA
RRVT-KD--TKFREFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPQDFN-----P
HHFLDDKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CL--GDGLAK--MELFLFLTTIMQ-NFRFKP
TQAP---HDIDVSP-KYVGFA--------TIPP----T---------YTLSFQPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDAVV--VLVLG-------------------LSC-
-LLFLSFW--RQSS-QRGNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 981)

PPGPT---PLPIIGNI-------LQI-----DI-K-----
----------NIT--K-SL----T--NL-SKVHGP-VFTLYLGM----K-PTVVLHGYEA
V---KEALVDLGED-FAG--RGSIP---I-FEKI-NKGL----------G-----VIFS-
-SG--N-SWKEIRRFSLMTLRNL--GMGKRSIE--SRVQEEARHLAEE------LR-KTR
----GS-P----C------------------------D-PTFILTYA----PSNVICSII
FQHRFDYNDP-IF-LTIIKIMSENVKILSS-----------PWM-----QV----Y----
-NIFPA-LI----DYLP-GS--HNTVIK-NVDYVKNYVVE---KIKEHQ----ESLDVNN
-PRDFID-----------CFLIKME-K--------ENNSEI-LKFTHENLA-ITVSDLFG
AGT-ETTS-TTLKYALLLLMKHPEVV----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYTDAVLHEIQRYIDLIPIN-LP
HAVT-RD--VKFRNYTI--PK---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFI--VLVLS-------------------LSC-
-LLLLSLW--RQSS-ERGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNF-------LQI-----DV-K-----
----------DIS--Q-SL----T--NL-SNVYGP-VFTLYMGM----E-PTVVLHGYEA
V---KEALIDHGEE-FAG--RGSFP---V-AERI-TKGL----------G-----IILS-
-NG--S-RWKEIRRFSLMTLRNL--GMGKRTIE--DHVQEEAQCLVEE------LR-KTN
----GS-P----Y------------------------D-PTFILSCA----PCNVICSII
FQNRFDYKDQ-DF-LTFMEKINENIRILSS-----------PWL-----QV----K----
SRAFPS-EN----IL---TV--FHSHRS-NSIWTKKKLTLPFPGAHQLD----LVLHISS
-PHFVLG-----------FYL--------------ANNNQL-SEFTLEHLA-TTVNDLFG
AGT-ETTS-TTLRYALLLLLKHPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVVGRI-RRPCMQDRNHMPYTDAMIHEVQRFIDLIPTS-VP
HAVT-CD--TKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIT--SLSSV-LHDS-KEFPNPEVFD-----P
GHFLDKNGNFK--KSE---PGSG-------------------------------------
------------------------GKRI-CA--GEGLAR--MELFLLLTTILQ-NFNMKS
LVHP---KDIDTTP-VANGF-A-------SLPP----P---------YQICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPTVL------L--ILTLL--------------------TSF
LLLLV--R--GHTK-ACGQL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--N-SF----M--Q-LREKYGD-VFTVHLGP----R-PVVMLCGTKA
I---REALVDQAEA-FSG--RGTVA---V-VEPI-LQGY----------G-----MIFA-
-NG--E-RWKALRRFSVATMKDL--GMGKRSVE--ERIKEEARCLVEE------LQ-KFQ
----GA-P----M------------------------D-PTFLFQSI----SANIICSTV
FGERFDYKDR-QF-LHLLDLIYQTFSLYSS-----------FSS-----QV----F----
-ELFSG-FL----KYFP-GA--HKQIFK-NMQEVLYYIGQ---SVEKHR----ATLDPSN
-PRDFID-----------TYLLRMEK---------EKSNPH-TEFHHQNLM-ISVVSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEVD---QVTGSH-RLPTLDDRTKMPYTEAVINEIQRFSDLAPIG-VP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-QYFEQPDTFN-----P
DHFLDANGALM--KNEAFMPFSV-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PVAP---EDIDISP-KEIGFG--------KVPP----T---------YQICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MC--T-S-------LMKISERYGP-VFTIHLGP----R-RVVVLCGYDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YAGVSFS-
-LS--L-SLSLSLSLSLSLSLSL--SLGVSLYR--PGWIAVAGFLLTAGST-------SA
----GA-N----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--QQPQL----Y----
-EMFSS-VM----RHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFHLKNLV-LTSLNLFF
GGT-ETVS-TTLRYGFLLLMKYPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDWAKMPYTEAVIHEIQRFGDMLPMG-VA
HRVI-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-KFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFLTTIMQ-NFRFKS
PQSP---KDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
CTLRIVLPGWQRDPSGTMSALGVT-----V--ALLVW-------------------VAV-
-LLLVSIW--KQVH-SSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNL-------YQL-----EW-K-----
----------NIP--K-SF----S---QLAQRFGP-VFTLYLGS----R-RVVVVHGYKA
V---REVLLDYKDE-FSG--RGDIPAFQA----HRDRG-----------------IIFN-
-NG--P-TWKDIRRFSLTTLRNY--GMGKQGNE--SRIQREAHFLLEA------LR-KTQ
----GQ-P----F------------------------D-PTFLIGCA----PCNVIADIL
FRKHFDYNDE-KF-LRLMYLFNENFQLLST-----------PWL-----QL----Y----
-NNFPS-LL----YFLP-GS--HRKVMK-NVAEVKEYVSE---RVKEHL----QSLDPNC
-PQDLTD-----------CLLVEMEK---------EKHSAE-PLYTMDGIT-VTVADLFF
AGT-ETTS-TTLRYGLLILMKYPEIE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RIPAIKDRQEMPYMDAVVHEIQRFITLVPSN-LP
HEAT-RD--TIFRGYVI--PK---------------------------------------
-----------------------GT-V-IVP--TLDSV-LYDN-QEFPDPEKFK-----P
EHFLDENGKFK--YSDYFKPFS--------------------------------------
-----------------------AGKRV-CA--GEGLAR--MELFLLLAAILQ-HFNLKP
LVDP---KDIDLSP-ANIGF-G-------CIPP----H---------YKLCVIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVL------L--FLALL--------------------TGL
LLLLV--Q--RHPN-AHGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--R-SF----L--R-FREKYGD-VFTVYLGP----R-PVVMLCGVEA
I---REALVDNAEA-FSG--RGKIA---I-TDPV-FQGY----------G-----VVFA-
-NG--N-RWNVLRRFSLTTMRDF--GMGKRSVE--ERIQEEAQCLIEE------LR-KSK
----GA-L----V------------------------D-PTFLFHSI----TANIICSIV
FGKRFHYQDQ-EF-LKILNLFYHTFSLASS-----------MFG-----QL----F----
-ELLSG-FL----KHFP-GA--HRQVYK-NLQEISTYIGH---SVEKHR----ETLDPSA
-PQDLID-----------SYLLQMEK---------EKSNPH-SEFSHRNLI-INTLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-ERIYKEIE---QVIGPH-RPPALDDRAKMPYTEAVIHEIQRFADLLPMG-VP
HIVT-QQ--TSFRGYII--PK---------------------------------------
-----------------------DT-E-VFP--LLSTA-LHDP-RYFEKPDTFN-----P
DHFLDANGALK--KNEAFIPFSL-------------------------------------
------------------------GRRI-CL--GEGIAR--NELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-QESGVG--------KIPP----K---------YQIRFLPH-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------M

PF00067 // ENSGT00880000137861_0_Domain_2 (708, 1067)

DNLI-TTVWDVFS
AGT-ETTS-LTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVVGRN-RSPCMQDRSRMPYTDAVLHEIQRYIDLVPSN-LP
HVAT-QD--VKFREYLI--PK---------------------------------------
-----------------------VG-S-ISS--ILKTL--ESE-TLFATPWTTQ-----S
M-------EFS--KPLYWS-----G-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--ALVLC-------------------FSC-
-LLLLSLW--KQTH-GNGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1103)

PPGPT---PLPIIGNI-------LQL-----NA-K-----
----------DIS--K-SL----S--KL-SETYGP-VFTLYLGW----K-PTVVLHGYEA
V---KEALVDHGEE-FSG--RGSFP---L-AERT-SKGL----------G-----VVFS-
-NG--M-TWRETRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSVV
FHTRFDYTDQ-DF-LTLMAKLNENLRILST-----------PWV-----QF----L----
-HTFPV-LI----DYLP-GS--HNKVLE-NAEFLKKFALK---KIKEHQ----ESLDIND
-PRDYID-----------CFLIKME-Q--------EKHNPQ-SEFTMENLT-ITVSDLFG
AGT-ETTS-STLRYGLLLLLKYPEVA----------------------------------
------------------------------------------------------------
-------AK-IQ----E---E---------------------------------------
--------------ID---RVVGRH-RSPCMQDRSSMPYTDAVLHEIQRYIDFVPTG-VP
HAVI-SD--IKFRNYVI--PK---------------------------------------
-----------------------GT-N-IIT--SLTSV-MHNN-KEFPNPERFD-----P
RHFLDKSGNFR--KSDYFMPFST-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPLGAT-T---V--FLVIC-------------------VSC-
-LLFLSAW--RKTP-RKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPV---AFPIIGNM-------LQL-----TK-T-----
----------NLP--Q-HV----L---ELSRTYGP-IFTIYLGS----E-RVVVLHGYEI
L---KETLIGLADE-FSA--RGRMP---L-FEKM-ATES----------G-----IVFS-
-NG--E-RWKQLRRFILTSLRNF--GMGKKSIE--ERILEETRFLMER------LR-NTH
----GR-P----F------------------------D-PTLFLTHA----VSNIICSII
FGDRFDYEDQ-KF-VTLINIIEENVNLQRS-----------RWT-----AL----Y----
-NFFPT-VM----DYVP-GP--HHKLFK-NAEKFRKFVLE---RVNMHK----PSLDPNC
-PRDFID-----------AFLIKMQ-E--------EQKNDQ-SNFSMGSLL-RSTVELFS
AGT-GTTS-VTLLFGLLILLKYPEIE----------------------------------
------------------------------------------------------------
-------EK-VH----K---E---------------------------------------
--------------ID---RVIGRS-RSPCMADRSQMPYTDAVIHEIQRYINLVPLS-LP
HAVT-RD--VHIRQYLI--PK---------------------------------------
-----------------------DT-T-IFP--ALNSV-LYDS-KEFPNPEQFK-----P
EHFLDENGAFK--KSDYFVPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLILTVILQ-NFTLKP
VVDL---KDIDITP-VTTFV-S-------NGPK----S---------YQLCVLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------

PF00067 // ENSGT00880000137861_0_Domain_2 (352, 1051)

MVVLHGYEA
V---KEALIDRGEE-FSG--RGHFP---L-AERA-NRGF----------G-----IIFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--ERVQEEAHCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FQKRFDYKDQ-QF-LNLMEKLNENTRIVST-----------PWI-----QI----C----
-NNFPP-II----DYFP-GT--HNKFLK-NIAFMESYISE---KVKEHQ----ESMDVNN
-PRDFID-----------CFLIKME-E--------EKQNQQ-SEFTIENLV-ITAADLLG
AGT-ETTS-TTLRYALLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVVGRN-RSPCMQDRGHMPYTDAVVHEVQRYIDLIPTN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------VS-L-FLL--HCNSM-FFYS-SNSQYDSYPL-----P
----SQGERSA--KLL-CVAV---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------IMKISERYGP-VFTIHLGP----R-RIVVLCGHDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-VFS-
-NG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLIEALRD-------TQ
----GA-N----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------SAG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNR----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFHLKNLV-LTSLNLFF
GGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDQARMPYTEAVIHEIQRFGDMLPFG-VA
HRVI-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-KFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFFTTIMQ-NFRFKS
PQSP---KDIDVSP-KHVGFA--------TIPP----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLTLL--------------------TSF
LLLLV--R--GHTK-AHGQL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPH---PLPLLGNL-------LQM-----DR-R-----
----------GLL--N-SF----M--R-LREKYGD-VFTVHLGP----R-PVVMLCGTEA
I---REALVDQAEA-FSG--RGTIA---V-FEPI-VQGY----------G-----LIFA-
-NG--E-RWKALRRFSVATMKDF--GMGKRSVE--ERIKEEAQCLVEE------LQ-KSQ
----GA-P----M------------------------D-PTFLFQCI----TANIICSIV
FGERFDYKDR-QF-LHLLDLLFQIVSLIST-----------FSS-----QV----F----
-ELFSG-FL----KYFP-GT--HRQISK-NLQEILDFIGQ---SVEKHR----ATLDPSN
-PRDFID-----------TYLLRMEK---------EKSNQH-TEFHHQNLI-ISVLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEVD---QVIGSH-CLPTLDNRTKMPYTEAVIHEIQRFSDLVPIG-LP
HRVT-KD--TSFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSAA-LHDP-QYFEQPDTFN-----P
DHFLDANGALK--KNEAFMPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PVAP---EDIDLTP-KYSGVS--------KIPP----T---------YQIHFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDSIST----AIL--LLILA-------------------LICL
LLT-T------S-SKGKGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---ALPFLGNL-------LQL-----RS-Q-----
----------DML--T-SL----T---KLSKEFGA-VYTVYLGP----R-RVVVLSGYQA
V---KEALVDQAEE-FSG--RGDYP---A-FFNF-TKGN----------G-----IAFS-
-NG--D-RWKALRKYSLQILRNF--GMGKRTIE--ERILEEGHFLLEE------LR-KTQ
----GK-P----F------------------------D-PTFVVSRS----VSNIICSVI
FGSRFNYDDD-RL-LTIIHLINENFQIMSS-----------PWG-----EM----Y----
-NIFPN-LL----DWVP-GP--HRRLFK-NYGRMKNLIAR---SVREHQ----ASLDPNS
-PRDFID-----------CFLTKMA-Q--------EKQDPL-SHFFMDTLL-MTTHNLLF
GGT-ETVG-TTLRHAFRLLMKYPEVQ----------------------------------
------------------------------------------------------------
-------VR-VQ----E---E---------------------------------------
--------------ID---RVVGRE-RLPTVEDRAEMPYTDAVIHEVQRFADIIPMS-LP
HRVT-RD--TNFRGFTI--PR---------------------------------------
-----------------------GT-D-VIT--LLNTV-HYDP-SQFLKPKEFN-----P
EHFLDANMSFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GEALAR--MELFLYLTAILQ-SFSLQP
LGAP---EDIDLTP-LSSGL-G-------NVPR----P---------YQLCVRAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPTV--VLLLS-------------------LSC-
-LLLLSLW--RQSS-ERRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNF-------FQI-----DS-K-----
----------NIN--Q-SF----T--KF-SKVYGP-VFTLYLGM----K-PSVVLHGYEA
V---KEALIDHGEE-FAG--RGSLP---V-AERI-TKGL-----------G----IIFS-
-NG--S-RWKEIRRFSLMTLRNL--GMGKRSIE--DRVQEEAQCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILSCA----PCNVICSVI
FQNRFDYNDQ-DF-LTFMEKVNENVRILSS-----------PWL-----QV----C----
-NNFPW-LF----DYCP-GS--HHTVLK-NADYIRSYIVE---KIKEHQ----ESLNVAN
-PRDFID-----------YYLIKQK-Q--------ENHNQQ-SEFTLEHLA-TTVGDLFT
AGT-ETTS-TTLRYALLLLLKHPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVVGRH-RSPCMQDRSHMPYTDAMIHEVQRFIDLIPTN-LP
HAVT-HD--TKFRNYII--PK---------------------------------------
-----------------------GT-T-VIT--SLSSV-LHDS-KEFANPEVFD-----P
GHFLDKNGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTTILQ-NFKLKS
LLHT---KDIDTTP-VANGF-A-------SLPP----H---------YKICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------FVC--FLVFV-------------------VFC-
-FCLFLFV-----C-FLCFVPP----------LDFF-------V--------S-I-----
----------YIF--L-SN----F-

PF00067 // ENSGT00880000137861_0_Domain_2 (326, 1252)

-QL-SNVYGP-VFTLYLGR----K-PAVVLHGYEA
V---KEALIDHGEE-FAG--RGSFP---V-AERI-TKGL----------G-----IVFS-
-NG--S-RWKEIRRFSLMTLRNL--GMGKRTIE--DRVQEEAQCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILSCA----PCNVICSII
FQNRFDYKDE-DF-LNLMKKLDENFNILSS-----------PWL-----QV----C----
-NNFPW-LF----DYCP-GS--HHTVMK-NTDYIKSYLLE---KIKDHQ----ESFNVAN
-PRDFID-----------YYLIKQE-Q--------ENHNQQ-SEFTLEHLA-TTVSNLFA
AGT-ETTS-TTLRYALLLLLKHPRVT----------------------------------
------------------------------------------------------------
-------AK-VQ----D---E---------------------------------------
--------------ID---RVVGRH-RSPCMQDRSHMPYTDAMIHEVQRFIDLIPNN-LP
HAVT-CD--TKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIT--SLSSV-LHDS-KEFPNPEIFD-----P
GHFLDGNGNFK--KSDYFMPFST-------------------------------------
------------------------GKRI-CA--GEGLAR--MELFLFLTTILQ-NFKLKS
LRHP---KDIDTTP-VANGL-T-------SLPP----P---------YKICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELLGISTT---L--PLVIC-------------------VTC-
-LVFLFVW--KKSYGW-GRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNL-------MQL-----NL-K-----
----------NLP--A-SL----S---KMAKEYGP-VYTLYFGP----Q-LTVVLHGYEV
V---KEALIDQADE-FLG--RGRFP---I-IEDN-QKG----------HG-----ILFS-
-NG--E-TWKQMRRFSLMTLRNF--GMGKRSIE--ERVQEEARCLVEE------LR-KME
----AQ-P----F------------------------D-PVFVFACA----PCNVICSIL
FNERFHYKNE-TF-LSLMYLLTENFKQISS-----------PWN-----QI----Y----
-NLWPT-LI----RHLP-GE--HKAFSK-RLDGVKNFILE---KVKAHQ----ESLDPNN
-PRDYID-----------CFLSKME-Q--------EKHKPE-SEFNLENLA-VCGSNLFT
AGT-ETTS-STLRWGLLLLMKHPEVE----------------------------------
------------------------------------------------------------
-------AK-VH----E---E---------------------------------------
--------------ID---RVIGRN-QSPCMKDKMRLPYTEAVLHEIQRYITLLPSD-LP
HAVT-RD--TKFKNYVI--PK---------------------------------------
-----------------------GT-T-VLP--LLSSV-LFDC-KEFPNPEKFD-----P
GHFLDKNGSFR--KTEYFVPFSL-GK----------------------------------
--------------------------RA-CA--GEGLAR--MELFLFFTTILQ-NFCLKP
LVEP---KEIDTTP-VVTGL-L-------NIPP----P---------YKLCLIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--VLVLC-------------------LSC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNM-------LQV-----DV-K-----
----------DIG--K-SF----T--NF-SKVYGP-VFTVYLGM----K-PTVVLYGYEA
V---KEALIDHGEE-FSA--RGHFP---V-AERI-NKGL-----------G----VIFT-
-NG--D-RWKQIRRFTLMTLRNF--GMGKRSIE--ERVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILSCA----PCNVICSII
FQNRSDYKDK-HF-LKLLEKLYANVNILSS-----------PWM-----QI----Y----
-NNFPA-LI----DYFP-AT--LNTLSN-NAVFIKSYILE---KVKEHQ----ESLDVNN
-PRDFID-----------CFLIKME-Q--------EKNNQQ-LEFTFEALV-TTAFDLFG
AGT-ETTS-TTLRYALLLLLKHPDVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVVGRH-RSPCMQDKSHMPYTDAVIHEVQRYIDLIPTD-LP
HAVT-HD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-VLP--FLTSV-LYDS-KEFSKPEMFD-----P
SHFLDESGKFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTSILQ-NFNLKS
LVDP---KDLDITP-VAKGF-A-------SVPP----L---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNKAGKLPPGPT---PIPFPGNL-------LQV-----RT-D-----
----------ATP--S-SCVFLHS---KLREKYGS-LFTVYMGL----W-PVVVLCGHEA
V---KEALINQTDE-FNG--HGEWT---S-IEQN-FQGH----------G-----VALA-
-NG--E-RWRILRRLSLTIFWDF--RMGKRSIE--ERIQDEASYLLEE------FR-KTK
----GA-P----I------------------------D-PTFLLSCS----VSNVISSVV
FGSRFDYEDK-QF-LNLLQLINESFTEMST-----------PWSSCLFPQL----Y----
-DMYSG-IM----QYLP-GR--HNRVYY-LIEELKDFIAS---RVKINE----ASFDSQN
-PRDFFD-----------CFLIKMHQ---------VSP-----------LL---PL----
------------------------------------------------------------
------------------------------------------------------------
----------

PF00067 // ENSGT00880000137861_0_Domain_2 (851, 980)

IH----K---E---------------------------------------
--------------IN---QVIGPH-QLPSVDDRVKMPYTDA----IQRLVDIVPMG-VP
HNVI-WD--IQFRGQLL--PE---------------------------------------
-------------------------------------------------PEAFY-----P
QHFPDELGRFK--KNGAFVPFSS-------------------------------------
------------------------EKRV-CL--GEAMAR--MELFLYFTSILQN-FSPRS
LVPP---ADIDVTP-KLSGFG--------NIPL----T---------MNSTSAICIVGAG
SC----------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
IMVLMSVW--RQR-KLWGKLPPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKVSGHGMG-AVGFGLGA----G-LV--------
-------------E-LGL--NGRGWAREW----K-STG--------------WVA-----
--G--S-QTRNSRSWDVQPLEYQ--NLGARHAV-------GEGWA---------------
----------------------------------------------Q----AGSQGS

PF00067 // ENSGT00880000137861_0_Domain_2 (538, 1250)

SIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------STG-----QL----Y----
-EMFYS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMRE---------EQNNPN-TEFYLKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPHVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKLHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDIIPMG-LA
RRVT-KD--TKFREFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSKPRDFH-----P
EHFLDENGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTNILQ-NFRFKS
PQLP---QDIDVSP-KHVGFA--------TIPR----S---------YTMSFQPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------RK-KRMDPVV--VLVLG-------------------LCC-
-LLLLSHW--KQNS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PFPIIGNI-------LQI-----DA-K-----
----------DIS--K-SL----T--KF-SERYGP-VFTVYLGM----K-PAVVLHGYQA
V---KEALVDLGEE-FAG--RGSFP---M-LDKV-SKGL----------GR----IVFT-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FHNRFDYKDE-EF-LKLLEKFNENVRILSS-----------PWL-----QV----C----
-NNFPA-LI----DYLP-GS--HKTLLK-NSDYVKNFIME---KVKEHQ----KFLDVNN
-PRDFID-----------CFLIKME-QH--------KDENH-LEFTLESLV-TTVFDLFG
AGT-ETTS-TTLRYSLLLLLKHPEVA----------------------------------
------------------------------------------------------------
-------DK-VQ----E---E---------------------------------------
--------------IE---RVIGRH-RSPCMQDRSRMPYTDAVIHEIQRFIDLVPNN-LP
HTVT-RD--IKFRNYFI--PK---------------------------------------
-----------------------GT-D-IMT--SLTSV-LHDE-KAFPNPKVFD-----P
GHFLDESGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLFLTSILQ-NFKLQS
LVEP---KDLDITA-VLNGF-V-------SVPP----S---------FQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MMLGG-A---FSI--FMALC-------------------LSC-
-LLILIAW--KWTS-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PIPFLGNF-------LQV-----RT-D-----
----------ATF--Q-SF----QK---LQKKYGS-VFTVYFGP----R-PVVVLCGHEA
V---KEALVDQADD-FSG--RGEMP---T-LEKN-FQGYG---------------LALS-
-NG--E-RWKILRRFSLTVLRNF--GMGKRSIE--ERIQEEAGYLLEE------LH-KVK
----GA-P----I------------------------D-PTLYLSRT----VSNVICSVV
FGKRFDYQDQ-RF-QSLMKMINESFVEMSK-----------PWA-----Q-L---Y----
-DMYWK-VM----QYFP-GR--HNYLYN-LIEDLKDFIAS---RVKINE----ASFDPSN
-PRDFID-----------CFLIKMHQ---------EKSDTH-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGFLLLLKYPEVE----------------------------------
------------------------------------------------------------
-------AK-IH----E---E---------------------------------------
--------------IN---QVIGTH-RTPRVDDRAKMPYTDAVIHEIQRLADIVPLG-VP
HNVT-RD--THFRGYLL--PK---------------------------------------
-----------------------GT-D-VYP--LFGSV-LKDP-KYFRYPDAFY-----P
QHFLDEQGRFK--KNDAFVVFSS-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLYFTSILQ-RFSLRS
LVPP---ADIDIAH-KISGF-G-------NIPP----V---------YELCFMAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEFSVL------L--LLALT--------------------TGF
LIFLVS-Q--SQPK-THGHF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPR---PLPFLGNL-------LQM-----DR-R-----
----------GLL--S-SF----I--Q-LQEKYGD-VFTVHLGS----R-PVVMLCGTDT
I---REALVNQAEA-FSG--RGTVA---V-LDPI-VQGY----------G-----VIFS-
-SG--E-RWKTLRRFSLATMRDF--GMGKRSVE--ERIKEEAQCLVEE------LK-KYQ
----GA-P----L------------------------N-PTFYFQCI----VANIICSIV
FGKRFDYTDH-QF-LHLLNLIYQTFSLMSS-----------LSS-----QV----F----
-ELFSA-IL----KYFP-GA--HRQISK-NLQEILDYIGH---SVEKHR----ATLDPSA
-PRDFID-----------TYLLRMEK---------EKSNHH-TEFHHQNLV-ISVLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------SFLIM
LKYPHVA-EKVQKEID---QVIGSH-RLPTLDDRTKMPYTDAVIHEIQRFTDLAPIG-LP
HKVT-KD--TLFRGYLI--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-RYFEQPDSFN-----P
DHFLDANGALK--TNEAFMPFST-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PVAP---KDIDLTP-NNSGAT--------KTPP----V---------YQIHFLSR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSVL------L--LLALL--------------------TGF
LLLLI--R--GQPK-AYSRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQM-----DR-G-----
----------GLL--K-SF----I--K-LCDKHGD-VFTVHLGP----R-PVVMLYGTET
I---KEALVDHSDA-FSG--RGAVA---V-IQPI-VQDY----------G-----VIFS-
-SG--E-RWKTLRRFSLATMRDF--GMGKRSVE--ERIKEEAQCLVEE------LK-KYE
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFDYTDH-QF-LHLLDLFYQTLSLISS-----------FSS-----QV----F----
-ELFSA-VL----KYFP-GT--HRQISK-NIQEILNYIGH---SVEQHK----ATLDPSA
-PRDFID-----------TYLLRMEK---------EKSNHH-TEFHHQNLL-ISVFSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVISAH-RVPTLEDRIKMPYTEAVIHEIQRFSDLAPIG-LP
HTVT-KD--TMFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-QYFEQPDKFN-----P
EHFLDANGALK--KSEAFLPFST-------------------------------------
------------------------GKRA-CL--GEGIAR--NELFLFFTALLQ-NFSLSS
PVAP---EDIDLTP-KESGFA--------KIPP----V---------YQICFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLSV--ALALC-------------------LSC-
-LLLLSLW--KQSS-GKGTL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPA---PLPVIGNI-------LQI-----DI-K-----
----------NIS--K-SL----T--SI-SRVYGP-VFTLYFGT----K-PIVVLHGYEA
V---KEALIDLGEM-FSG--RGSFP---V-AEKI-NKGF-----------G----ILFS-
-NG--K-RWKEMRRFSLITLRNF--GMGKRSIE--ERVQEEARCLVEE------LK-NTK
----GL-S----C------------------------D-PTFILSYA----PCNVICSII
FRNRFDYKDQ-NF-LSLLKKLDENLRIMSS-----------PWI-----QV----C----
-NNFPA-VI----DYLP-GS--HNTILK-NFASVKNYVLE---KIKEHQ----KSLDNNN
-PQDFID-----------CFLIKME-E--------EKHNQQ-SEFTIETLL-GTVTDLFA
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRD-RSPCMQDRSRMPYTDAMVHEVQRYIDLIPNS-LP
HAVT-CD--VKFRDYLI--PK---------------------------------------
-----------------------GT-T-IIT--SLTSV-LHDN-KEFSNPEIFD-----P
GHFLDESGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTTILQ-NFTLKS
PVDL---KDIDITP-ITNSF-G-------HVPP----P---------FQLCFIPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDITGL----GTL--VLILL-------------------ISCI
VIYST--W--NS-MYRKRNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPLIGNL-------LQI-----KR-G-----
----------EMV--K-SL----T---EFGKQYGP-VYTLYLGP----R-PVIVLNGYQA
V---KEALIDQGEE-FSG--RGKLV---V-ADLI-FGG----------FG-----VVFS-
-NG--D-RWKQLRRFSLMTLRDF--GMGKRSIE--ERIKEEAQCLQVE------LH-KYK
----QT-P----T------------------------D-PQNILVQA----VSNVICSVV
FGNRFEYENS-EF-LKLLRLFNETFQMMSS-----------TWG-----QS----Y----
-DIYSGIFM----NYIP-GP--HQKIDK-VVARQLEFVSE---RVKKNQ----ETIDFNS
-PRDFID-----------CFLIKMQ-Q--------ETQNPT-SEFNLKNLL-MTVLNLFV
AGT-ETVS-STLRNGILLLLKYPHIQ----------------------------------
------------------------------------------------------------
-------EK-LH----K---E---------------------------------------
--------------ID---VVIGQN-RSPNIDDRSKMPYMDAVIHEIQRFTDILPMN-LP
HSVI-KD--TAFQGYTI--PK---------------------------------------
-----------------------DT-D-VYP--MLCSV-LRDP-TQFTTPENFN-----P
EHFLDDSGCFK--KSDAFMPFST-GK----------------------------------
--------------------------RI-CL--GEGLAR--MELFLFLTTILQ-NFTLTS
ETQI---TESDITP-RMAGF-A-------NVPI----S---------YKVSFVPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------PPPPP--

PF00067 // ENSGT00880000137861_0_Domain_2 (268, 1070)

-PPVFLGVF-------RGDLGEFGTP-P-----
----------CTF--Q-SL----L---KLSERYGP-VFTVWLGP----R-PVLVLRGTGA
V---REALVGNPEA-FAG--RGRMP---T-LEST-FRG----------YG-----VVFS-
-DG--E-RWRQLRRFSLTVLRDF--GMGRRSIE--SRIQEEAQELLRE------FQ-KTQ
----GR-P----F------------------------D-PTFLLSCA----VSNVICSIV
FGQRFPYQEP-EF-LRLLQMMNDSFREMST-----------SWA-----QL----Y----
-DMAEP-LL----RWLP-GP--HRRIPR-LLGRMRGFIAR---RVRESA----RSLDPRS
-PRHFID-----------AFLIQMD-K--------EKDNPN-SEFTMENLE-LTTLNLFF
AGT-ETVS-STLRFGFLYLMKHPQVE----------------------------------
------------------------------------------------------------
-------EK-VF----E---E---------------------------------------
--------------IS---RVIGSG-RAPAVADRALMPFTDATIHEIQRCSDLIPMN-VP
HRVT-RD--TEFRGFHI--PK---------------------------------------
-----------------------GT-D-VYP--LLSSV-LHDP-ESFRNP----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDLGG-A---LTI--FLVLS-------------------MSC-
-LFILMVW--SQIN-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PIPFLGNV-------LQV-----RI-D-----
----------AFF--H-SF----MK---LQKKYGN-VFTVYLGP----R-PVVILCGHDA
V---KEALVDQADD-FSG--RGEIA---T-IERN-FQGYG---------------LVMA-
-NG--E-RWKVLRRFSLTVLRNF--GMGKRSIE--ERIQEEAGYLLEE------FR-KTK
----DT-P----I------------------------D-PTFFLSPT----VSNVISSVV
FGNHFDYEDK-QF-LSLLGMINETFIEMSV-----------PWA-----Q-L---Y----
-DRYSG-VM----QYLP-GR--HNHIYD-LIEDLKALIAS---RVKVNE----ATLDLQN
-PQDFID-----------CFLIKMHQ---------DKKDPH-TEFSLRHLV-LTTLNLFF
AGT-ETVS-STLRYGMLLLMKYPQVE----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------II---QVIGPH-RIPTVDDRIKMPYMDAVIHEIQRLTDIVPLG-VP
HTVV-RD--THFRGYFL--PK---------------------------------------
-----------------------GI-D-VYP--LLGSV-LRDP-KYFQHPNDFY-----P
QHFLDEQGRFK--RNDAFVAFSS-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLYFTSILQ-NFSLRS
LVPP---ADIDITP-RISGF-G-------NIPP----V---------YKLCLVAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGML----LV--ALLAC-------------------LT--
VMVLMSVW--RQR-KIWGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKLSERYGP-VFTIHLGP----R-RIVVLCGYDA
V---KEALVDQAEE-FSG--RGKQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGYLIEAFRD-------TR
----GA-V----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYENK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFYS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRNFID-----------SFLIRLQE---------EQKNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVCEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDMIPMG-LA
RRVT-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSKPQDFN-----P
QHFLDEKGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTTIMQ-NFRFKS
PQSP---QDIDVSP-RLVGFA--------TIPP----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELSVL------L--FLALL--------------------TGL
LLLLV--Q--RHPN-AHGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPR---PLPLLGNL-------LQM-----DR-R-----
----------GLL--R-SF----H--R-FREKYGD-VFTVYLGP----R-PVVMLCGVEA
I---REALVDNAEA-FSG--RGKIA---I-TDPV-FQGY----------G-----VVFA-
-NG--N-RWKVLRRFSLTTMRDF--GMGKRSVE--ERIQEEAQCLIEE------LR-KSK
----GA-L----V------------------------D-PTFLFHSI----TANIICSIV
FGKRFHYQDQ-EF-LKILNLFYHTFSLASS-----------MFG-----QL----F----
-ELLSG-FL----KYFP-GA--HRQVYK-NLQEINAYIGH---SVEKHR----ETLDPSA
-PQDLID-----------SYLLQMEK---------EKSNPH-SEFSHRNLI-MNTLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-ERIYKEIE---QVIGPH-RPPALDDRAKMPYTEAVIHEIQRFADLLPMG-VP
HIVT-QQ--TSFRGYII--PK---------------------------------------
-----------------------DT-E-VFP--LLSTA-LHDP-HYFEKPDTFN-----P
DHFLDANGALK--KNEAFIPFSL-------------------------------------
------------------------GRRI-CL--GEGIAR--NELFLFFTTILQ-NFSVAS
PVAP---EDIDLTP-QESGVG--------KIPP----T---------YQIRFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDSLV--VLVLC-------------------LCC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPVIGNI-------LQI-----DI-K-----
----------DIS--K-SL----T--NL-SKVYGP-VFTLYFGL----E-RMVVLHGYEA
V---KEALIDLGEE-FSG--RGHNP---L-ANRA-NRGF-----------G----IVFS-
-NG--K-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FHKRFDYKDQ-QF-LNLMEKLNENIKIGSS-----------PWI-----QI----C----
-NNFPL-FI----DYFP-GA--HNKLLK-NIAFVKSYVLE---KVKEHQ----ESMDMNN
-PRDFID-----------CFLIKME-K--------EKHNQQ-SEFTIENLE-NTAVDLFA
AGT-ETTS-TTLRYALLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRN-RSPCMQDRSHMPYTDAVVHEVQRYIDLLPTS-LP
HAVT-SD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-ILI--SLTSV-LHDN-KEFPNPEMFD-----P
HHFLDEGGNFK--KSNYFMPFSA-GK----------------------------------
--------------------------RI-CV--GEALAR--MELFLFLTSILQ-NFNLKS
LVDP---KDLDTTP-VLNGF-A-------SVPP----F---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--VLLLS-------------------LFF-
-LLFLSLW--RLSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPIIGNF-------FQV-----DM-K-----
----------DIR--Q-SL----T--NF-SKTYGP-VYTLYVGS----Q-PTVVLHGYEA
L---KEALVDHGEE-FSG--RGRLP---I-CEKV-AKGQ----------G-----IAFS-
-HG--N-VWKATRHFTVKTLRNL--GMGKGTIE--DKVQEEAKWLVKE------LK-KTN
----GS-P----C------------------------D-PQFIMGCA----PGNVICCII
LQNRFDYEDK-DF-LNLIEKVNEAVKIISS-----------PGI-----QV----F----
-NIFPI-LL----DYCP-GN--HNIYLK-NYTWVKSYLLE---KIKEHE----ESLDVSN
-PRDFID-----------YFLIERN-Q--------ENANQW-MNYTLEHLA-IMVTDLFF
AGI-ETVS-STMRFALLLLMKYPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPSMQDRSHMPYTNAMVHEVQRYIDIGPNG-LL
HDVT-CD--TKFRNYFI--PK---------------------------------------
-----------------------GT-A-VLT--SLTSV-LHDS-KEFPNPEMFD-----P
GHFLDENGNFK--KSDYFIPFSA-------------------------------------
------------------------GKRM-CL--GESLAR--MELFLFLTTILQ-NFKLKS
LVDP---KDINTTP-ICSSL-S-------SVPP----T---------FQMRFIPL-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSF-
-VLLFSLW--RQSS-GRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----DV-K-----
----------DIC--K-SF----S--NF-SKVYGP-VFTVYFGM----N-PVVVLHGYET
V---KEALIDNAEE-FSG--RGILP---I-SERI-TNGL-----------G----IISS-
-NG--K-RWKETRRFSLTTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSVV
FQKRFDYKDE-NF-LTLMKRFTVNFRILTS-----------PWI-----QV----C----
-NNFPL-LI----DCFP-GT--HNKLLK-NVALTKSYIRK---KVKEHQ----ATLDVNN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFTIENLV-GTVADLFV
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---HVIGRH-RSPCMQDRSHMPYTDAVIHEIQRYIDLVPTG-VP
HAVT-TD--IKFRNYLI--PK---------------------------------------
-----------------------GT-I-IIT--LLTSV-LQDD-KEFPNPKIFD-----P
GHFLDENGNFK--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTTILQ-NFNLKS
VADL---KNLNTTS-ATRGI-I-------SLPP----S---------YQICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-NSKGKLPPGPT---PLLFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------IMKISERYGP-VFTIHLGP----R-RVVVLCGHDA
V---REALVDQAEE-FSG--RGEQATFNL----F-FKG--------------YYGVTFS-
-TL--E-RAKLLRHFSIATLRNF--GVGGIQEK--A------GFLIQALL--------GT
----RG-E----I------------------------N-PTFFLSRT----VSNVISSI-
------------F--------------TAT-----------

PF00067 // ENSGT00880000137861_0_Domain_2 (582, 1107)

YTG-----QL----Y----
-EMFSS-VM----THLP-GP--QQQAFK-ELQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIHLQE---------EEKNPN-TEFYMQNLV-MTTLNLFI
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEETD---RVIGKN-RQPKFEDQARMPYTEAVIHEIQRSGDVIPMA-VA
HRVN-KD--TKFQDVFL--LKGT-------------------------------------
--------------------------E-MFP--MLGSV-FF------SNPQYFNP-----
-------QQFK--KSDAFVPFSI-GKRPLFAARPLLTPAGASLTQLSFLWCSWYFP----
--------GFQVPVRIYPL-------------------------VIS-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------LCS-LPMALFI--VLVVC-------------------LSC-
-LILFSLW--NRRH-AKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQL-----DI-K-----
----------NIA--K-SL----S--IL-AKDYGP-VFTVHFGM----K-PTVVLYGYEA
V---KEALIDRAEE-FSG--RGSYP---V-IDHI-FQGL-----------G----IVFS-
-NG--E-IWKQTRRFSLTVLRNM--GMGKKTIE--DRIKEEALCLIDE------LK-KTN
----GS-P----C------------------------D-PTFLLSCV----PCNVIASVI
FQNRFDYGDE-KF-HTLIHYFHENFRLVST-----------PWI-----QL----Y----
-NFFPS--L----HYFP-GS--HNELFK-IIANQKKFIME---KVKEHQ----ESLDINN
-PQDFID-----------YFLIKME-K--------EKHNKQ-SDFTMDNLI-VTTWDLFS
AGT-ETTS-TTMKYGLLLLLKHPEVS----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVIGRD-RSPCMQDRSRMPYTDAVLHEIQRYINLVPIN-LP
HTVT-QD--VKFREYVF--PK---------------------------------------
-----------------------GT-E-IMV--SLTSL-LYDE-KEFPNPQKFD-----P
GHFLDESGNFK--KSDHFMAFS-AGK----------------------------------
--------------------------RV-CV--GEGLAR--MELFLILTSILQ-HFTLKP
LIDP---KDIDTTP-STIGL-G-------SIPP----S---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------CTMEWVC-V---VTL--LLVIC-------------------VSC-
-HFFISSK--GKRL-HKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1233)

PPGPT---PLPLIGNL-------LQI-----KS-G-----
----------ETL--K-SL----LK---LHEKYGP-VFTVYLGT----R-PVLVLCGHQA
V---KEALIDKAEE-FSG--RTTKP---T-LERA-VEGYG---------------VCFC-
-NG--E-RWKQLRRFSITVLRSF--GMGKKSIE--ERIQEEAQFLLEE------LR-KTK
----GK-P----L------------------------E-PTDLLSRA----VCNIISSIV
FGERFDYENE-EF-QALMTIIHNFFWEMSS-----------TWS-----QL----Y----
-DMFPT-LL----KYFP-GP--HTRVYN-IVSDALRFIGK---RVKKNQ----ETLDSNF
-PRDFID-----------CFLIQMEK---------EKDNPL-SEFNIKNME-LTIFDLFF
AGT-ETVG-LTLRYGFLLLIKYPEVQ----------------------------------
------------------------------------------------------------
-------AK-VH----E---E---------------------------------------
--------------ID---RVIGHN-RTPKSEDRRQMPYTDAVIHEIQRVSDIAPMG-VA
HMVT-CD--TEFRGYFI--PK---------------------------------------
-----------------------GM-E-VFP--LLSTV-LHDP-TMFKSPSVFN-----P
ENFLDENGCFK--KNDASVPFSS-GK----------------------------------
--------------------------RI-CL--GESLAR--MELFLFFTTILQ-SFQLKP
LVPR---EDLDPTP-LENGF-L-------NVSP----V---------YHLSIIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDSVST----AIL--LLLLG-------------------FVCL
LLTL-------N-SRGKGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPK---PFPVLGNL-------LQL-----RS-Q-----
----------DML--T-SL--T-----KLSKEYGS-VYTVHLGL----R-RVVVLSGYQA
V---KEALVDQGEE-FSG--RGDYP---V-FFNF-TKGN----------G-----IAFS-
-NG--D-RWKVLRRFSVQILRNF--GMGKRSIE--ERILEEGSFLLAE------LR-KTE
----GE-P----F------------------------D-PTFVLSRS----VSNIICSVL
FGSRFDYDDE-RL-LTIISLINDNFQIMSS-----------PWG-----EM----Y----
-NLFPS-LL----NWVP-GP--HRRLFQ-NFGRVKDLIAH---SVRDHQ----ASLDPNS
-PRDFID-----------CFLSKMAQ---------EKQDP-XXXXXXXXXX-XXXXXXXX
XXX-XXXX-XXXXXXXXXXXXXXXXX----------------------------------
------------------------------------------------------------
-------XX-XX----X---X---------------------------------------
--------------XX---XXXXXX-X---XXXXXXX-XXXXXXXXXXXXXXXX--X-XX
XXXX-XX--XXXXXXXX--XXXXXXXX---------------------------------
-----------------------XX-X-XXX--XXXXX-XXXX-XXXXXXXXXX-----X
XXXXXXXXXXX--XXXXXXXXXX-------------------------------------
------------------------XRRL-CL--GESLAR--MELFLYLTAILQS-FSLRP
LGAP---ESIDLTP-LSSGLG--------NLPR----P---------FQMCLRAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MTALGIT-----V--ALLVW-------------------VTA-
-LLCAFLW--KQMY-SSRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIVGNV-------LQL-----EL-N-----
----------NIP--K-SF----T---RLAERFGP-VFTLYLGS----N-RVVVLHGYQA
V---KEVLLQHKNE-FSG--RGEYHVYRA----HKHQG-----------------ITFN-
-NG--P-TWKETRRSALTILRDF--GMGKEGNE--ARIQREIPFLLDA------LR-KTN
----GQ-P----F------------------------D-PTFVVGSA----PCNVIADIL
FRKRFDYEDR-TS-LRLQTLFNENLYLIST-----------PWL-----LL----H----
-NSFPS-FL----NCLP-GS--HRKVMK-NVSELKDYALA---RLKEHQ----QSLAPSC
-PRDFTD-----------CLLMEMEK---------EKYKAE-PGYNLDNIA-ATVADLFF
AGT-VTTS-ATLKYGLLVLMKHPEVE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPN-RIPSIKDKLEMPYMDAVVHEIQRFTNLLPSN-LN
HEAT-QD--TVFRGYII--PK---------------------------------------
-----------------------GT-V-LIP--TLDSL-LFDK-QEFPDPDKFK-----P
EHFLDEKGKFK--YSDYFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLFFTAILQ-HFNLKS
LVDP---KDIDLTP-IVNGF-A-------SIPP----D---------YKLCLLPRSQA--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ES-ATMGPVA--LLVLC-------------------LSC-
-LLLLSLW--IQSS-GRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNL-------LQL-----DV-K-----
----------NIS--K-SL----S--NL-SKVYGP-VFTVYFGM----K-PTVVLHGYEA
V---KEALIDKGEE-FSG--RGSFP---V-AEKA-NQGF-----------G----IIFS-
-NG--K-RWKEIRRFSLMTLRNL--GMGKRNIE--DRVQEEACCLVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FQKRFDYKDK-VF-LNIMERFNENVKILNS-----------PWI-----QI----Y----
-NNCPT-LL----DYFP-GS--QNKIFK-NVDFIKSYVIE---KTKEHQ----ASLDIHN
-PRDFID-----------YFLIKME-Q--------EKHNPH-GEFTIDNLT-ITVSDFFG
AGT-ETTS-TTLRYALLLLLKHPEVS----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRE-RSPCMQDRSHMPYTDAMVHEVQRHLNFLPTN-LP
HAVT-CD--VNFRNYLI--PK---------------------------------------
-----------------------GT-T-IIT--NLTSV-LRDD-KEFPNPEKFD-----P
GHFLDEEGNFK--KSDYFMAFSA-GK----------------------------------
--------------------------RM-CA--GEGLAR--MELFLFLTTILQ-KFTLKA
VVDI---KDLDVTP-VMNGF-A-------SVPP----P---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSTL------L--LLTLL--------------------LSF
LVLLV--R--GYPK-TRGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQI-----DR-G-----
----------GLL--N-SF----R--R-FQEKYGD-VFTLHLGS----K-PVVMLYGTEA
I---REALVDQAEA-FSG--RTTIA---V-LKPT-FMDY----------G-----VIAA-
-NG--E-RWKTLRRFSLVTMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGQRFDYKDG-QF-LRLLGLFYQTFSIISS-----------LYT-----QM----F----
-ECFPG-FL----KYFP-GT--HVQVSK-NLQELLDYIEH---SVEKHR----VNMDASN
-PRDFID-----------TYLLRMEK---------EKSNPH-TEFHHRNLV-TTVLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQREID---HVIGSD-RPPSLDDRPKMPYTEAVIYEIQRFSDLVPTG-VP
HKVN-KD--TYFRGYLL--PK---------------------------------------
-----------------------DT-E-VYP--ILSSA-LHDP-KYFEQPYTFN-----P
DHFLDASGALK--KNEAFMPFSI-G-----------------------------------
-------------------------KRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PMAP---KDIDLNP-KENGFG--------RLPP----E---------YQICFLAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------LRSSK-------GRV-----AR-G-----
--------------------------G-LREKYGD-VFTVHLGT----R-PVVMLCGTEA
L---REALVDHAEA-FSG--RGTVA---V-LEPV-VQGY----------G-----VIFA-
-NG--E-RWKALRRFSLATMRDF--GMGKRSVE--EQIKEEARCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFDYKDR-QF-LRLLDLFYQTFLLISS-----------FSS-----QV----F----
-ELFSG-IL----KYFP-GV--HKQIFK-NVQEILNYIGH---NVEKHR----TTLDPSN
-PRDFID-----------TYLIRMEK---------VQNRV--------------------
------AV-HCFCE----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GTEIL
CCLPFCA

PF00067 // ENSGT00880000137861_0_Domain_2 (908, 1250)

-EKVQKEID---QVIGSH-RPPTLDDRTKMPYTDAVIHEIQRFSDIVPIG-LP
HKVT-KD--TLFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSAA-LHDP-RYFEQPDDFN-----P
DHFLDANGALK--KNEAFMPFSI-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
PVAP---KHIDLRP-KESGVS--------KILP----K---------YQIHFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----LV--ALLAC-------------------LT--
VMVLMSVW--QQR-KSRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISERYGP-VFTIHLGP----R-RVVVLCGHDA
V---KEALVDQAEE-FSG--RGEQATFNR----V-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSIATLRDF--GVGKRGIE--ERIQEEAGFLIEALRG-------TR
----GA-N----I------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-GF-LSLLRMMLGSFQFTAT-----------STG--Q---L----Y----
-EMFSS-VM----KHLP-GP--QQQAFK-KLQGLEDFIAK---KVEHNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EEKNPN-TEFYLKNLV-MTALNLFI
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-QQPKFEDRVKMPYMEAVIHEIQRFGDVIPMS-LA
RRVI-KD--TKFRDFFL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LKDP-RFFSNPQDFN-----P
QHFLDEKGQFK--KSDAFVPFAI-------------------------------------
------------------------GKRN-CF--GEGLAR--MELFLFFTTIMQ-NFRFKS
PQSP---KDIDVSP-KHVGFA--------TIPR----N---------YTMSFLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--VLVLC-------------------LSS-
-LLLLFLW--RQSP-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQV-----DV-K-----
----------NIG--K-SL----T--NF-SKVYGP-VFTVYFGM----K-PAVVLHGYEA
V---KEALIDHGEE-FSG--RGHFP---V-AERI-NKGL-----------G----IIFS-
-NG--D-RWKEIRRFTLMTLRNF--GMGKRRIE--ECVQEEARCLVEE------LR-KTK
----AS-P----C------------------------D-PLFILSFA----PCNVICSII
FRNRFDYVDQ-TL-LNMMEKFDENHRIMSS-----------PWL-----QV----C----
-NNFPA-LI----DYLP-GS--HNKLFK-NFAYVKSYVLE---KIKEHQ----ESLDMNN
-PQDFID-----------YFLIKME-Q--------EKQNPQ-SKFTIENLL-ATVIDVFG
AGI-ETTS-TTLRYGLLILLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVVGRH-RSPCMQDRSHMPYTDATVHEIQRYIDLVPTN-LP
HAVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-VLT--SLTSA-LHDD-REFPNPERFD-----P
GHFLDESGNFK--KSDYFMPFSI-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTTILQ-NFTLKS
LADP---KDIDITP-IASGL-A-------HVPP----S---------YQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPIL--VLVFT-------------------LSC-
-LFLLSLW--RQSS-ERGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----NV-K-----
----------DIC--Q-SF----T--NL-SKVYGP-VYTLYLGR----K-PTVVLHGYEA
V---KEALVDHGEE-FAG--RGRLP---V-FDKA-TNGM-----------G----IIFS-
-KG--N-VWKNTRRFSLTTLRNL--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FQDRFDYKDR-DF-LNLMEKLNEITKIMST-----------PWL-----QV----C----
-NTFPV-LL----DYCP-GS--HNKVFK-NYACIKNFLLE---KIKEHE----ESLDVTI
-PRDFID-----------YFLINGG-Q--------ENGNYP-LKNRLEHLA-ITVTDLFS
AGT-ETTS-TTLRYALLLLLKYPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---HVIGKH-RRPCMQDRSHMPYTDAMIHEVQRFIDLVPNS-LP
HEVT-CD--IKFRNYFI--PK---------------------------------------
-----------------------GT-N-VIT--SLSSV-LRDS-KEFPNPEKFD-----P
GHFLDENGKFK--KSDYFMPFST-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTSILQ-NFNLKP
LVHP---KDIDVTP-MLIGL-A-------SVPP----A---------FQLCFIPS-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLVT--VLVLT-------------------VSC-
-LLLLSLW--RQNS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPFIGNI-------LQI-----DV-K-----
----------DVS--K-SL----T--NF-SKVYGP-VFTLYFGT----K-PSVVLHGYEA
V---KEALVNLREE-FSG--RGSFP---I-SERV-NRGL-----------G----ILFS-
-NG--M-KWREIRRFSIMTLRNF--GMGKRSIE--DRVQEEAQCLVEE------LR-KSK
----GA-P----C------------------------D-PTFILGCA----PCNVICSII
FQKRFDYKDQ-SF-LNLMEKFNENLRLMST-----------PWI-----QV----C----
-NTFPA-II----DHLP-GS--HNQVLK-NFFYVKNYVLE---KVKEHE----KTLDMAN
-PRDFID-----------CFLIKME-Q--------EKHNPK-SEFTIENLV-ATVTDMFG
AGT-ETTS-TTLRYGLLLLMKHTDVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IE---RVVGRN-RSPCMGDRSHMPYTDAVVHEIQRYIDLIPTN-LP
HSVT-CD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIT--SLTSV-LYDD-KEFPNPEKFD-----P
GHFLDESGNFK--KSDYFVPFST-GK----------------------------------
--------------------------RM-CA--GEGLAR--MELFLFFTTILQ-NFNLKP
LIDV---KDIDTTP-ITSGF-G-------HVPP----S---------YQACFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPLGTS-T---V--LLVIC-------------------ISC-
-LLLSAFW--KSQANKR-KM

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPP---PLPIIRKA-------LRL-----KT-N-----
----------HLD--L-TL----C---KLSKSYGP-IFTLYFGP----R-PVVVLHGYGA
V---KEALIERADE-FAA--RGRMP---S-MEKY-FQGK----------G-----IIFS-
-NG--E-TWKQLRRFALTTLRNF--GMGKKSIE--ERIQEEAQYLLEQ------LQ-GTK
----EE-P----F------------------------D-PTFLLNCA----TSNIICSVV
FAKHYDYDDK-KF-LAIMALMHENFEILNS-----------PWG-----QL----A----
-NLFPS-FM----DLIP-GP--HHRVGT-NFKKAKVFVME---EMEAHR----ETLDPSS
-PRDFID-----------CFYIKMD-Q--------EKNTEA-SEFTIENLL-MSAINLFG
AGT-ETTS-TTLRYGLLILQKYPEIE----------------------------------
------------------------------------------------------------
-------EK-VQ----E---E---------------------------------------
--------------ID---RVVGRS-RAPCMSDRGQMPYTDAVIHEIQRFISLIPLS-LP
HSVN-KD--TVFRGYTI--PK---------------------------------------
-----------------------DT-T-VFP--LLTSV-LHDD-KEFPNPREFD-----P
QHFLNKDGTFR--KSDYFMPFSA-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLASILQ-NFKLKP
LTDP---QDIDIKP-HLSSI-G-------NVPP----P---------YRLCVVPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVL--VLVLT-------------------VSC-
-LLLLLVW--RQNS-GRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPLIGNI-------LQI-----DI-K-----
----------DIS--K-SL----A--NF-SKVYGP-VFTLYFGM----K-PTVVVHGYEA
V---KEALDDLGEE-FSG--RGNFP---I-VERM-NNGL----------G-----IVFS-
-NG--T-KWKELRRFSLMTLRNF--GMGKRSIE--DRIQEEARCLVEE------LR-KTN
----GS-L----C------------------------D-PTFILSCA----PSNVICSVV
FHNRFDYKDE-NF-LNLMEKLNENFEILNS-----------PWM-----QV----C----
-NAIPA-FL----DYLP-GS--HNKALK-NFAEIKSYILK---RVKEHQ----ETLDMDN
-PRDFID-----------CFLIKME-Q--------EKDNPH-SEFTTESLM-ATVADVFV
AGS-ETTS-TTLRYGLLLLMKHTEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----K---E---------------------------------------
--------------ID---HEIGRN-RSPCMQDRTRMPYTDAMVHEVQRYVNLIPNN-VP
HAAT-CN--VKFRNYVI--PK---------------------------------------
-----------------------GT-D-LIT--SLTSV-LHDD-KEFPNPKIFD-----P
AHFLDENGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RM-CV--GEALAR--MELFLFLTTILQ-NFDLKS
LVDT---KDIDTTP-VASTF-G-------CVPP----S---------YQLYFIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ATMLTSGLL----LV--ALLTC-------------------LT--
VMALMSVW--RQK-KLGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPFLGNY-------LQL-----NTQQ-----
-----------MY--N-S-------LMKLRERYGP-VFTVHVGP----R-RIVVLCGHEV
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIEALRD-------TR
----GA-F----L------------------------D-PTFFLSRT----VSNVISSIV
FGDRFDYEDK-EF-LSLLRMMLGSFQFTAT-----------SMG--Q---L----Y----
-EMFYS-VM----KHLP-GP--QQQAFK-ELQGLEDFIAK---KVEQNQ----RTLDPNS
-PRDFID-----------SFLIRMQE---------EQNNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPDVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGKN-RQPKFEDRAKMPYTEAVIHEIQRFGDIIPMG-VA
RRVT-KD--TGFREFLL--PKGT-------------------------------------
--------------------------E-VFP--MLGSV-LRDP-KFFSNPQDFH-----P
QHFLDENGQFK--KSDAFVPFSI-------------------------------------
------------------------GKRY-CF--GEGLAR--MELFLFLTNILQ-NFRFKS
PQLP---KDIDVSP-KLVGFA--------TIPR----N---------YTMSFQPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDWIVI----AL----LLLS-------------------ITCL
LLA-R------S-PQNKGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQL-----RS-R-----
----------DML--A-SL----T---KLSQEYGP-IFTVHLGT----R-PVVVLSGYEA
V---KEALVDKADE-FSG--RGEYP---V-FHDF-TKGN----------G-----IAFS-
-NG--E-KWKVLRRFSIQILRNF--GMGKRSIX--XXXXXXXXXXXXX------XX-XXX
----XA-P----F------------------------D-PTFVLSRS----VSNIICSVI
FGSRFDYEDE-RL-LKIIQLINDNFKIMSS-----------PWG-----E-----Y----
-NIFPG-LL----RWIP-GP--HHRLFQ-NYGCMKDLIDH---SIHEHQ----ARLDSSC
-PLDFID-----------CFLIKMA---------------E-SYFHMETLV-KTTHNLLF
GGT-ETVG-TTLRHAFLLLMKYPHIQ----------------------------------
------------------------------------------------------------
-------AR-VQ----E---E---------------------------------------
--------------ID---HVVGRG-RRPTLEDRSTMPYTDAVLHEVQRFADVIPMN-LP
HRVI-RD--TAFRGFLL--PK---------------------------------------
-----------------------GT-D-IIT--LLNTV-HYDQ-TQFQTPKEFN-----P
AHFLDSKEDFK--KSPAFMPFSA-GR----------------------------------
--------------------------RL-CL--GEPLAR--MELFLFLAGILQ-NFTLQP
LCPL---EEIDVTP-LSSGL-G-------NVPR----P---------FQLRMLPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPAV--VLVFI-------------------LSC-
-LVLLSLW--RQRS-ERGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPLIGNF-------LQI-----DV-K-----
----------DIS--R-SL----T--NL-SKVYGP-VFTLYLGM----K-PTVVLHGYEA
V---KENLFQC----------------------F-TISS-----------G----IIFS-
-NG--S-RWKETRRFTLMTLRNL--GMGKRSIE--DCVQEEAQSLVEE------LR-KTK
----GS-P----C------------------------D-PTFILGCA----PCNVICSII
FQNRFDYKDH-HF-LTLMEKVNENSRILSS-----------PWF-----QV----C----
-NNFSS-LI----DYCP-GS--HHTITK-NFNYIRSYLLE---KIKEHQ----ESLDDAN
-PRDFID-----------CYLIKMK-Q--------ANHNQQ-SEFSLENLA-ITLSDLFA
AGT-ETTS-TTLRYALLLLLKHPHVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---QVVGRD-RSPSMQDRSRMPYTDATVHEVQRFIDLIPTN-LP
HAVT-CD--IKFRDFFI--PK---------------------------------------
-----------------------GT-T-IIT--SLSSV-LHDS-KEFPNPEVFD-----P
GHFLDKNGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFLFLTTILQ-NFKLKS
LVHP---KDIDTNP-VVNGF-A-------SLPP----P---------FQLCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MGALGIT-----I--ALLVW-------------------VVT-
-LLLISIW--KQIH-SSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNL-------LQM-----DI-K-----
----------NIP--K-SF----T---RLAKRYGP-VFTLYLGS----R-RVVVLHGYEA
V---KEVLLKYKNE-FSG--RGEIPVFQE----YKDKG-----------------IIFN-
-NG--P-TWKDVRRFSLSILRDY--GMGKQGNE--ARIQREAQFLLEE------LR-KTQ
----GK-P----F------------------------D-PTFLLGCA----PFNVIADIL
FHRRFAYNDK-TA-LRLMHLFNEDFYLLST-----------PWL-----QL----Y----
-NNYSN-YL----RYMP-GS--HRKVMK-NVSEIKVYALE---RAKENL----QSLDLNC
-SRDVTD-----------CLLTEMEK---------EKHNGKPPMYTMENIA-VTLADLFF
AGT-ETTS-TTLRYGLLILMKYPEIE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---KVIGPT-RIPAVKDRLEMPYMDAVVHEIQRFINLVPSN-LP
HEAT-QD--TMLQGYFI--PK---------------------------------------
-----------------------GT-V-VIP--TLDSL-LYDK-QEFSEPEQFR-----P
EHFLNENGKFK--YSDYFKPFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLLLTAILQ-HFNLKS
LVEP---KDIDLKP-ITVGF-G-------SIPP----S---------YKLCLIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLS-------------------LSC-
-LLLLSLW--KQGS-KRGKF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIVGNL-------LQI-----DI-K-----
----------DIT--K-SL----A--NF-SKVYGP-VFTLYFGL----K-RTVVLHGYEV
V---KEALIDLGDE-FSG--RGLIP---V-VERA-NREY-----------G----IVFS-
-NG--N-RWKEIRRFSLMTLRNF--GMGKRSIE--DRVQEEAHYLLEE------LR-KTK
----AS-P----C------------------------D-PTFILGCA----PCNVICSII
FQKRFDYKDQ-QF-LSLMERLNENTKILSS-----------PWL-----QI----C----
-NSLPP-II----DYFP-GT--HNKLLK-NVALIKSFILE---KVKEHQ----ESVDINN
-PRDFID-----------CFLIKMK-K--------EEHNQQ-SEFIIENLV-NTALDLFG
AGT-ETTS-TTLRYALLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------IG---HVVGRN-RSPCMQDRGHMPYTDAVVHEVQRYIDLIPTN-LP
HAVT-SD--VQFRNYLI--PK---------------------------------------
-----------------------GT-T-ILT--SLTSV-LHDN-KEFPNPEKFD-----P
HHFLDEGGNFK--KSNYFIPFST-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFIFLTSILQ-NFNLKP
LVDP---KNLDITP-VVNGF-A-------SVPP----F---------YQLCFIPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLGSELL----LV--AILAY-------------------LS--
VMVLVSVW--KQ--KVRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPYIGNY-------LQL-----NTKD-----
-----------MY--S-S-------ITELSERYGP-VFTIHLGP----R-PVVVLYGYDA
V---KEALVDQAEE-FSG--RGEQATYNT----L-FKG--------------YGV-TFS-
-SG--E-RAKQLRRFSIATLRDF--GVGKRSVE--ERIQEEAACLVKMLQS-------TS
----GA-P----I------------------------D-PTVYLSQT----VSNVINSIV
FGDRFDYEDK-EF-LELLRMMGQINRFAAS-----------PTG-----QL----Y----
-DMFHS-VM----KYLP-GP--QQQIIK-NTKELEDFMVR---KVKQNQ----STLDLNS
-PRNFID-----------SFLIHMQE---------EKKNPD-SEFNIQNLV-MTSLNLFF
AGS-ETVS-STMRYGFLLLMKYPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKVHEEID---RVIGRN-RQPQFEDRMKMPYTEAVINEIQRFANLAPLG-IP
RKTI-QN--TTFRGFFL--PKDT-------------------------------------
--------------------------E-VFP--ILGSL-LTDP-KFFPSPKDFN-----P
QNFLDDKGQLK--KNAAFVPFSV-------------------------------------
------------------------GKRF-CL--GDGLAR--MELFLFFTTILQ-NFRFKF
PKKP---EDIDESP-KPLGFA--------RIIP----H---------YTMSFLPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLFI--VLVIC-------------------LSC-
-LILFSLW--NASY-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPI---PLPIVGNI-------LQL-----NT-K-----
----------NIS--K-SL----S--ML-GKDYGP-VFTVYFGM----K-PTVVLYGYKA
V---KEALIDRGEK-ENM--NGVIS---VLFSKR-LSGI-----------G----IVFS-
-NG--K-KWKHTRCFSLMVLRNM--GMGKKTIE--DRIQEEALYLVEL------LR-KTN
----AS-P----C------------------------D-PTSILSCV----PCNVICFVI
FQTRFDHSDQ-KF-QNFIKYFHENCEILST-----------PWI-----QL----Y----
-NAFPL--L----HYLP-GC--HKDFFK-NFAHQKEFILG---KIKEHQ----ETLDINN
-PRDFID-----------YFLIKME-K--------EKHNKE-SEFTMENLV-ITILDLFG
AGT-DTMS-TTMRYGLLLLLKHPEIA----------------------------------
------------------------------------------------------------
-------AK-VQ----K---E---------------------------------------
--------------IH---HVIGRH-RSPCMQDRSCMPYTDAVVHEIQRYIDLIPTI-LP
HAVT-QD--MQFREFLI--PK---------------------------------------
-----------------------GT-N-ILI--HLSSV-LHDE-KEFPNPERFD-----P
GHFLDESGNFK--KSDYFMPFS-AGK----------------------------------
--------------------------RI-CA--GESLAR--MELFLILTSILQ-NFTLKP
LVDP---KDIDVTP-ISNGL-S-------SIPP----F---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQL-----DI-R-----
----------NIS--K-SF----S--NF-SKLYGP-VFTVYFGL----K-PTVVLHGYEA
L---KEALIDHGEE-FSG--RGALP---L-IERS-QKGH-----------G----IIFS-
-TG--K-RWKEMRRFSLLTLRNF--GMGKRSIE--DCVQKEARCIVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSIV
FQNRFQYEDK-NF-LTLMERFNENFRIAST-----------PWI-----QV----C----
-NIFPF-LI----DYFP-GT--HNKFLK-NGAFTKSYILE---KVKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFTVENLV-STVFDLFV
AGT-HTTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYMDAVLHEIQRYIDLIPNG-LL
HTVT-SD--IKFRNYLI--PK---------------------------------------
-----------------------GT-N-IVP--SLTSV-LYDD-KEFPNPEVFD-----P
GHFLDESGNFK--KSENFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
LTDL---KALNATP-TAKGL-V-------SMLP----S---------YQICFTPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVLGV--FLGLV-------------------LAC-
-LLLLSLW--RQNS-QRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQV-----DL-K-----
----------NIS--K-SL----R--DL-SKVYGP-VFTLYLGR----K-PAVVLLGYEA
V---KEAMVDHGEE-FAG--RGSFP---V-ADKI-GQGF-----------G----IVFS-
-SG--K-IWKTMRRFSLVTLRNF--GMGQRSIE--ERVQEEARYMVGE------LR-KTN
----GS-P----C------------------------N-PTFILGCG----PCNVICSIV
FQNRFDYKDK-EF-LNFMHVLNENVEILSS-----------PWM-----QI----C----
-NNFPF-MI----DYLP-GK--HRKLLE-NFTFLKHYFSA---KATQHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKNNPK-TEFIRENLI-FSASDLFA
AGT-ETTS-TTLRYSLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----K---E---------------------------------------
--------------ID---HVIGRN-RSPCMQDRIHMPYTDAVLHEIQRYIDLLPTS-LP
HATT-CD--MKFRNYLI--PK---------------------------------------
-----------------------GT-T-VIA--SLSSV-LYDD-KEFPNPEKFD-----P
GHFLDENGKFK--KSDYFFPFST-GK----------------------------------
--------------------------WI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
PVDL---KDLDITP-VANGF-V-------SVPP----E---------FQICFTPI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MTALGIT-----V--ALLVW-------------------LVT-
-LLLISIW--KHIH-SSWKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIVGNI-------FQL-----DL-K-----
----------NIP--K-SF----T---MLAERYGP-VFTVYLGS----R-RIVVLHGYKA
V---KEVLLHYKNE-FSG--RGEIPTFQV----HKDKG-----------------VIFN-
-NG--P-TWRDTRRFSLTTLRDF--GMGKQGNE--QRIQREAHFLLEA------LR-KTH
----GQ-P----F------------------------D-PTFLIGCA----PCNVISDIL
FRQHFDYNDK-TC-LRLMSMFNENFYLLST-----------GWI-----QL----Y----
-NNFSG-YL----RYLP-GS--HRKLMK-NISEIKDYALE---RVKDHR----DSLEPSC
-PRDFTD-----------TLLMEMEK---------EKYSAE-PIYTLDNIA-VTVADMFF
AGT-ETTS-TTLRYGLLILMKYPEVE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPN-RIPAIKDRLDMPYLDAVVHEIQRFIDLIPSN-LP
HEAT-RD--TVFRDYII--PK---------------------------------------
-----------------------GT-V-VIP--TLDSV-LYDS-QEFPEPEKFK-----P
EHFLNENGKFK--YSDHFKAFS--------------------------------------
-----------------------AGKRV-CV--GEGLAR--MELFLFMAAILQ-HFNLKS
LVDP---KDIDLSP-ITIGF-A-------KIPP----H---------YKLCVIPRSQV--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MALLT--ILGIC-------------------LSC-
-LIVFFLW--NQHH-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIVGNI-------LQV-----DI-K-----
----------NIS--E-SL----S---MLAKEYGP-VFTVHLGM----K-PTVVLHGYEA
L---KEALIDRGDE-FSG--KMQSS---L-LSRV-NQGL----------G-----IIFS-
-NG--E-TWKQTQRFSLMALRSM--GMGKKTIE--DRIQEEVLHLLEA------LR-KTN
----GA-P----C------------------------D-PSFLLACV----PCNVISAVI
FQHRFDYNDE-IL-QKITEDFYRIIKTLES-----------PWA-----QL----C----
-SIYP--VL----YCLP-GS--HKAFLK-QEFGHYEFISK---EIKRHQ----ESLNPSN
-PQDFID-----------HFLIKME-K--------EKQNKK-SEFTMENLV-ITISDLFS
AGT-ETTS-TTMKYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-IQ----E---E---------------------------------------
--------------IA---RVVGKH-RSPCMQDRNHMPYTDAVLHEIQRYIDLVPIP-LP
RQTT-QD--VEFRGYHI--PK---------------------------------------
-----------------------GT-S-VMT--CLTSV-LHDD-KEFPCPEKFD-----P
GHFLDERGNFK--KSEHFMAFSA-GR----------------------------------
--------------------------RA-CI--GEGLAR--MEMFLILTNILQ-HFTLKP
LVNP---EDIDTTP-ALTGL-L-------SLPP----P---------YELCFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSIL------L--LLALL--------------------VGF
LLLLV--R--GHPK-SRGNF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQL-----DR-G-----
----------GLL--N-SF----M--Q-LREKYGD-VFTVHLGP----R-PVVMLCGTDT
I---KEALVGQAED-FSG--RGTIA---V-IEPI-FKEY----------G-----VIFA-
-NG--E-RWKALRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFDYTDR-QF-LRLLELFYRTFSLLSS-----------FSS-----QV----F----
-EFFSG-FL----KYFP-GA--HRQISK-NLQEILDYIGH---IVEKHR----ATLDPSA
-PRDFID-----------TYLLRME-KVSPAWMREEKSNHH-TVFHHENLM-ISLLSLFF
AGT-ETSS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVA-EKVQKEID---QVIGSH-RLPTLDDRSKMPYTDAVIHEIQRFSDLVPIG-VP
HRVT-KD--TMFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-QYFDHPDSFN-----P
EHFLDANGALK--KSEAFMPFST-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
HLAP---KDIDLTP-KESGIG--------KIPP----T---------YQICFSAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MSALGVT-----V--ALLVW-------------------VAV-
-LLLVSIW--KQVH-SSWNL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPF---PLPIIGNL-------YQL-----EW-K-----
----------NIP--K-SF----S---QLAQRFGP-VFTLYLGS----R-RVVVVHGYKA
V---REVLLDYKDE-FSG--RGDIPAFQA----HRDRG-----------------IIFN-
-NG--P-TWKDIRRFSLTTLRNY--GMGKQGNE--SRIQREAHFLLEA------LR-KTQ
----GQ-P----F------------------------D-PTFLIGCA----PCNVIADIL
FRKHFDYNDE-KF-LRLMYLFNENFQLLST-----------PWL-----QL----Y----
-NNFPS-LL----YFLP-GS--HRKVMK-NVAEVKEYVSE---RVKEHL----QSLDPNC
-PQDLTD-----------CLLVEMEK---------EKHSAE-PLYTMDGIT-VTVADLFF
AGT-ETTS-TTLRYGLLILMKYPEIE----------------------------------
------------------------------------------------------------
-------EK-LH----E---E---------------------------------------
--------------ID---RVIGPS-RIPAIKDRQEMPYMDAVVHEIQRFITLVPSN-LP
HEAT-RD--TIFRGYII--PK---------------------------------------
-----------------------GT-V-IVP--TLDSV-LYDN-QEFPDPEKFK-----P
EHFLDENGKFK--YSDYFKPFS--------------------------------------
-----------------------AGKRV-CA--GEGLAR--MELFLLLAAILQ-HFNLKP
LVDP---KDIDLSP-ANIGF-G-------CIPP----H---------YKLCVIPRS----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELGVL------L--LLTFT--------------------VGF
LLLLAS-Q--NRPK-THGHL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPFLGNL-------LQM-----NR-R-----
----------GLL--R-SF----M--Q-LQEKYGD-VFTVHLGP----R-PVVILCGTDT
I---REALVDQAEA-FSG--RGTVA---V-LHPV-VQGY----------G-----VIFA-
-NG--E-RWKILRRFSLVTMRNF--GMGKRSVE--ERIKEEAQCLVEE------LK-KYK
----GA-L----L------------------------N-PTSIFQSI----AANIICSIV
FGERFDYKDH-QF-LRLLDLIYQTFSLMGS-----------LSS-----QV----F----
-ELFSG-FL----KYFP-GV--HKQISK-NLQEILNYIDH---SVEKHR----ATLDPNT
-PRDFIN-----------TYLLRMEK---------EKSNHH-TEFHHQNLV-ISVLSLFF
AGT-ETTS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------SFLIM
LKYPHVA-EKVQKEID---QVISSH-RLPTLDDRIKMPYTDAVIHEIQRFADLAPIG-LP
HRVT-KD--TMFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-RYFDHPDTFN-----P
EHFLDANGTLK--KSEAFLPFST-------------------------------------
------------------------GKRT-CL--GEGIAR--NELFIFFTALLQ-NFSLAS
PVAP---EDIDLTP-INSGAG--------KIPS----P---------YQINFLSRCVG--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLAV--VLVLC-------------------LSC-
-LLLLSLW--KQSS-GKGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPILGNI-------LQL-----DV-K-----
----------NIG--K-SL----S--NL-SNTYGP-VFTVYFGL----R-PTVVLHGYEA
V---KEALIDQGEE-FSG--RGSLP---M-SQRV-NKGY-----------G----IIFS-
-NG--K-RWKEIRRFCLMTLRNF--GMGKRSIE--DRVQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFLLGCA----PCNVICSII
FQNRFDYTDQ-NF-RNLLEKFNENLRIMSS-----------PWI-----QI----C----
-NSFPI-LI----DYFP-GS--HNKVFK-NFAYVRSYVLE---KVKEHQ----ATLDINN
-PRDFID-----------CFLIKME-Q--------EKHNQE-MEFTFENLI-ASVFDLFG
AGT-ETTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYMDAVVHEIQRYIDLVPTN-LP
HAVT-RD--VKFRNYLI--PK---------------------------------------
-----------------------GT-T-IVT--SLSSV-LHDD-KEFPNPEVFD-----P
AHFLDESGNFK--KSDYFMAFSA-GK----------------------------------
--------------------------RN-CV--GEGLAR--MELFLFLTTILQ-KFTLES
VVDP---KDLDTAP-VSSGF-G-------HVPP----P---------YQICFTPVI----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--ALVLC-------------------FSC-
-LLLLTLW--RQRS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPM---PLPILGNI-------LQI-----DI-K-----
----------NIS--K-SL----T--NL-SKVYGP-VFTVYLGL----R-PTVVLHGYEA
V---KEALIDHGEV-FSG--RGSFP---V-GDRV-TKGL-----------G----IIFS-
-TG--S-RWKVMRRFSIMTLRDF--GMGKRSIE--DRVQEEARCLMEE------LR-KTE
----SS-P----C------------------------D-PTFLLGCA----PCNVICSII
FNNRFNYKDQ-HF-LKFMRKLDENVQILSS-----------PWI-----QV----C----
-NNFPV-LF----NIFS-GS--HKKLFK-NITDLKQYFME---KIKEHQ----ESLDMNN
-PRDFID-----------CFLIKME-E--------EKGNPQ-TEFTTEALI-NTVNDLFG
AGT-ETTS-TTLRYGLMLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-IQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDKSSMPYTEAVLHEIQRYIDLLPTN-LP
HAVT-CD--IKFRNYLI--PK---------------------------------------
-----------------------GT-T-IMT--SLTSV-LHDS-KEFPNPEKFD-----P
GHFLDKSGKFK--KSDYFMPFST-GK----------------------------------
--------------------------RI-CA--GEGLAR--MELFIFLTTILQ-NFRLKS
VVDP---KDLDTTP-VFNGF-V-------SVPP----A---------YRICFIPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MEPSIL------L--LLALL--------------------VGF
LLLLV--R--GHPK-SRGNF

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPR---PLPLLGNL-------LQL-----DR-G-----
----------GLL--N-SF----M--Q-FREKYGD-VFTVHLGP----R-PVVMLCGTDT
I---KEALVGQAED-FSG--RGTIA---V-IEPI-FKEY----------G-----VFFA-
-NG--E-RWKALRRFSLATMRDF--GMGKRSVE--ERIQEEAQCLVEE------LR-KSQ
----GA-P----L------------------------D-PTFLFQCI----TANIICSIV
FGERFDYTDR-QF-LRLLELFYRTFSLLSS-----------FSS-----QV----F----
-EFFSG-FL----KYFP-GA--HRQISK-NLQEILDYIGH---IVEKHR----ATLDPSA
-PRDFID-----------TYLLRMEXKVSPAWMREEKSNHH-TEFHHENLM-ISLLSLFF
AGT-ETGS-TTLRY----------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GFLLM
LKYPHVT-EKVQKEID---QVIGSH-RPPSLDDRTKMPYTDAVIHEIQRFADLAPIG-LP
HRVT-KD--TMFRGYLL--PK---------------------------------------
-----------------------NT-E-VYP--ILSSA-LHDP-QYFDHPDTFN-----P
EHFLDADGTLK--KSEAFMPFST-------------------------------------
------------------------GKRI-CL--GEGIAR--NELFLFFTTILQ-NFSVSS
HLAP---KDIDLTP-KESGIA--------KIPP----T---------YQICFSAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MLASGLL----VA--ALLAC-------------------LS--
VMVLMSVW--RRR-KLLGKLPPGPT---PLPFIGNY-------LQL-----NTEQ-----
-----------MY--N-S-------LMKISERYGP-VFTIHLGP----R-RIVVLCGQDA
V---KEALVDQAEE-FSG--RGEQATFDW----L-FKG--------------YGV-AFS-
-NG--E-RAKQLRRFSITTLRDF--GVGKRGIE--ERIQEEAGFLIQAFRD-------TH
----GA-F----I------------------------D-PTFYLSRT----VSNVISSIV
FGDRFEYEDK-EF-LSLLRMMLGSFQFTAT-----------STG--Q---V----S----
-FPC---------YDLP-TP--SPPSLK-L--GL--------------------------
-----TE-----------S-PL-SLQ---------EKQNPN-TEFYMKNLV-LTTLNLFF
AGT-ETVS-TTLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------AKIHEEID---RVIGKN-RQPKFEDRAKMPYTEAQFP---------------
---------------LP--CQGT-------------------------------------
--------------------------E-VFP--MLGSV-VKGG---FSEPSFQQ------
------------------------------------------------------------
----------------HPSFFS

PF00067 // ENSGT00880000137861_0_Domain_4 (1163, 1251)

SSGKRY-CF--GEGLAR--MELFLFLTTIMQ-NFRFKS
PQVP---KEIDVSP-KHVGFA--------TIPP----N---------YTMSFLLR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVV--VLVLG-------------------LSC-
-LLLFLLW--RQSS-GRRKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQI-----DV-R-----
----------DIS--K-SF----T--NF-SKVYGP-VFTLYFGM----K-PTVVVHGYEA
V---KEALDDLGEE-FSG--RGSFP---I-VEKT-NRGH-----------G----IIFS-
-NG--T-KWKEIRRFSLMTLRNF--GMGKRSIE--DRIQEEARCLVEE------LR-KTN
----GS-P----C------------------------D-PTFILGCA----PCNVICSIV
FQKRFDYKDT-NF-LVLMEKFNENFKILNS-----------PWM-----QV----Y----
-NVFPA-FI----DYLP-GS--HKKVLK-NFAYVKSYVLE---KVKEHQ----ESLDIHN
-PRDFID-----------CFLIRME-Q--------EKDNKH-SEFTMESLM-ATVTDLFV
AGT-ETTS-TTLRYGLLLLLKYPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGQN-RSPCMQDRSHMPYTDAMVHEIQRYINLIPNN-VP
HAAT-CN--LRFRNYFI--PK---------------------------------------
-----------------------GT-D-LIT--SLTSV-LHDD-QEFPNPEVFD-----P
GHFLDENGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RM-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
LVDP---KDIETIP-IANTF-G-------HVPP----L---------YKLCFISI-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPFV--VLVLC-------------------LSC-
-LLLLSLW--RQSS-GRGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PLPIIGNI-------LQL-----DI-R-----
----------NIS--K-SF----S--NF-SKLYGP-VFTVYFGL----K-PTVVLHGYEA
L---KEALIDHGEA-FSG--RGALP---L-IERS-QKGH-----------G----IIFS-
-TG--K-RWKEMRRFSLLTLRNF--GMGKRSIE--DCVQKEARCIVEE------LR-KTN
----AS-P----C------------------------D-PTFILGCA----PCNVICSIV
FQNRFQYEDK-NF-LTLMERFNENFRIAST-----------PWI-----QV----C----
-NIFPF-II----DYFP-GT--HNKFLK-NGAFTKSYILE---KVKEHQ----ESLDINN
-PRDFID-----------CFLIKME-Q--------EKDNQQ-SEFTVENLV-STVFDLFV
AGT-HTTS-TTLRYGLLLLLKHPEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----E---E---------------------------------------
--------------ID---RVIGRH-RSPCMQDRSHMPYMDAVLHEIQRYIDLIPNG-LL
HTVT-SD--IKFRNYLI--PK---------------------------------------
-----------------------GT-N-IVP--SLTSV-LYDD-KEFPNPEVFD-----P
GHFLDENGNFK--KSENFMPFSA-GK----------------------------------
--------------------------RI-CV--GEGLAR--MELFLFLTTILQ-NFNLKS
LTDL---KALNATP-TAKGL-V-------SMLP----S---------YQICFTPV-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VDSSLVT-V---F--DLVFC-------------------ILC-
-VFLISAW--RKAFGR-GKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PLGPV---PLPSIGNM-------LQL-----DT-M-----
----------N-----------------XXKDYGP-VFTLQLGF----E-HVVVLHGYKA
V---KEALIDHGDK-FAD--RGHLP---V-FEFA-SNG----------LG-----LLFS-
-NG--E-RWKQIRRFSLMTLRNF--GMGKRSIE--ERVQEEAKCLVEE------LK-KTN
----GL-P----C------------------------D-PTFILGCA----PCNVICSVL
FQKHFEYKDQ-KF-LYLMKLLNESTKIISS-----------PWI-----QL----Y----
-NFLPA-FR----AYLP-GE--HKRLFR-ILEEIKSFILE---RVKEHQ----KILDPSS
-PQDYID-----------CYLSKMQ-Q--------EKQNQE-SAFTIENLA-QMASDIFI
AGS-ETTS-TTLRYGLLLLLKHPEIA----------------------------------
------------------------------------------------------------
-------GK-IH----E---E---------------------------------------
--------------ID---RVIGRN-RSPCMEDRNKMPYTNGVVHEIQRYIDLIPTN-LP
HAVT-ED--VKFRQYLI--PK---------------------------------------
-----------------------GT-K-IIP--VLSSV-LYDD-EEFPNPDKFD-----P
RHFLDASGNFK--KSDYFIPFST-GK----------------------------------
--------------------------QI-CV--GESLAR--MELFLFFTTILQ-NFTLKS
PIDP---KDIDTTP-IVSGF-G-------RLPP----F---------YELCFVPFKNM--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MGLGW-A---VTM--FLELF-------------------LSC-
-LLIFIAW--KRMN-KGGKL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1252)

PPGPT---PIPFLGNL-------LQV-----RT-D-----
----------ATF--R-SL----MK---LSEKYGP-VFTVYMGP----R-PVVVLCGHKA
V---KEALVDQADD-FSG--RGQLA---S-VEQN-FKGHG---------------VVMS-
-NG--D-RWKSLRRFSLTILRDF--GMGKRSIE--ERIQEEAGYLLEE------FR-KTK
----GA-P----I------------------------D-PTFFLSRS----VSNIISSIV
FGSRFDYEDK-QF-LKLLQLVNECFSEMST-----------PWT-----Q-L---Y----
-GMYSG-VM----QYLP-GR--HHHTYYL-VEELKDFIAS---RVKINE----AAFDYQN
-PRDFID-----------CFLIKMRQ---------DKNNPH-TEFNLKNLV-LTTLNLFF
AGT-ETVS-STLRYGFLLLMKHPEVE----------------------------------
------------------------------------------------------------
-------AK-IH----E---E---------------------------------------
--------------IN---QVIGPH-RLPRVEDRVKMPYTDAVIHEIQRLLDIVPMG-VP
HTVT-RD--TQFRGYLL--PK---------------------------------------
-----------------------GT-N-VFA--LLGSV-LKDP-KYFRYPDAFY-----P
QHFLDEKGRFK--KNEAFVPFSS-GK----------------------------------
--------------------------RI-CL--GEGMAR--MELFLYFIFILQ-NFSLRS
LVPP---ADINITP-KLSGF-G-------NIPP----T---------YKLCLVAR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MELLGGV-T---V--VLLVC-------------------IAC-
-LLSFAAW--KGRS-GKGKM

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1251)

PPGPA---PLPILGNL-------LQV-----KP-S-----
----------NMT--K-TL----Q---KLSEEYGP-VFTVHLGS----D-PVVVLYGHDV
V---KEALVDRADE-FAA--RGHMP---I-GDRT-NKGL----------G-----IIFS-
-NN--E-LWLQGRRFSLTTLRNF--GMGKRSIE--ERIQEESDYLLEE------IN-KTK
----RT-P----F------------------------D-PTFMLSCA----VSNVICSIV
FGKRYDYKDK-KF-LALMNNMNNIFEMMNS-----------RWG-----QL----Y----
-QMFSN-IL----DYLP-GP--HNNIFA-EFDALKAFVAE---EVKLHQ----ASLDPSS
-PQDFID-----------CFLCKMQ-E--------EKDRPN-SSFYMKNLI-TSTFDLFL
AGT-ETTS-TTLRYGLLLLLKYPKIQ----------------------------------
------------------------------------------------------------
-------EK-IQ----E---E---------------------------------------
--------------ID---QVVGQS-RKPCVADRTQMPYTDAVVHEIQRFITLIPLA-LP
HTVT-KD--TTFRDYII--PK---------------------------------------
-----------------------GT-T-VFP--VLASV-LHDS-KEFPNPHEFN-----P
EHFLNKNGSFR--KSNFFMPFSA-GK----------------------------------
--------------------------RI-CP--GEGLAR--MEIFLLIATILQ-KFTLKS
VVNP---QELNITP-TLSGT-G-------NVPP----A---------YQLCAVPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPVL--VLVLT-------------------VSC-
-LLLLLVW--RQNS-GRGRL

PF00067 // ENSGT00880000137861_0_Domain_2 (261, 1250)

PPGPT---PLPLIGNI-------LQI-----DI-K-----
----------DIS--K-SL----A--NF-SKVYGP-VFTLYFGM----K-PTVVVHGYEA
V---KEALDDLGEE-FSG--RGNFP---I-VERM-NNGL----------G-----IVFS-
-NG--T-KWKELRRFSLMTLRNF--GMGKRSIE--DRIQEEARCLVEE------LR-KTN
----GS-L----C------------------------D-PTFILSCA----PSNVICSVV
FHNRFDYKDE-NF-LNLMEKLNENFEILNS-----------PWM-----QV----C----
-NAIPA-FL----DYLP-GS--HNKALK-NFAEIKSYILK---RVKEHQ----ETLDMDN
-PRDFID-----------CFLIKME-Q--------EKDNPH-SEFTTESLM-ATVADVFV
AGS-ETTS-TTLRYGLLLLMKHTEVT----------------------------------
------------------------------------------------------------
-------AK-VQ----K---E---------------------------------------
--------------ID---HEIGRN-RSPCMQDRTRMPYTDAMVHEVQRYVNLIPNN-VP
HAAT-CN--VKFRNYVI--PK---------------------------------------
-----------------------GT-D-LIT--SLTSV-LHDD-KEFPNPKIFD-----P
AHFLDENGNFK--KSDYFMPFST-GK----------------------------------
--------------------------RM-CV--GEALAR--MELFLFLTTILQ-NFDLKS
LVDT---KDIDTTP-VASTF-G-------CVPP----S---------YQLYFIPR-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------