Query Results 

-------MAGGEDRGDEEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SFT------SPAPLTG------------------------PTS---SPVGPPSS-LRASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------A----------------------------PESPPVPQ-----------------
----------------------------------------SPP-----------------
------------------------------------------------------------
----------------GQASLE--------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAEA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPCV--L----LQAQRSLEPEPKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEEEDQDMLNVESVEAGKEVPAPAPPLPLLSGVPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLGGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
ITLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAP
ALRARLTHFLAQRARRVA------LLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGEEDRGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGGLPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIQAVNSVASTTGTLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTSGTDVDLRTQLMLYESALRFED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRT-PEPG
-------STGP------ASP------VGST------SFP---------------------
------------------------------------------------------------
---------GPTLLTS------------------------P---GISPTGPASGL-RTSV
NLFP-----TISVGPSVDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGAT-VDETD--GSS---
------------------------------------------------------------
--------------------------------------------------PSGTRELW--
--DSPEPAS---APRTPQSPVSRI--L----LRTQQSLEPEPKEPVLPPSPKAE------
---PVHELPTRVPKLCIGDLDFSDLGEDEDQDTLNMASVESEKTFPLLPHPPSSLSGGSP
P-----PPPPPPPILGSLPP----------------PPPPPP-PPILGSCPPP-PPLAAP
FSRS-ALDG

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

PTLPTKRKTVKL---FWRELKLAGGPGFSG----------NRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------KSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELAP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNLSVPVAVSSGP--GQGDADSHATMKSLLTSRPEDTV
-HSRRSRGMVQSSSPVTHTA---VGASTVSPEETSASSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------RAGEEDRGDGEPVSLVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFFEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHTETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLGALPDQDSFYDVTDALEQQGMEALVQRHLSKAGTDVDLRAQLVLYENALRLED
GDLEEAV---TGGRRTTRRKPSSEEGKRSRR------------SLE------VRS-PEPG
-------STGP------ASP------VVST------STT---------------------
------------------------------------------------------------
---------SPVLLTS------------------------PT--SSPAGPPASG-LHSTL
SLFP-----TISVAPSSDSSC-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGA-MPDDMD--GR----
------------------------------------------------------------
---------------------------------------------------PDTRESR--
--HSQESTP---TPRTPQSAAPRI--L----LCAQQSLEPEPREPLAPPSPKAE------
---PVWELPARVPRLCIGDLDFSDLGEDEDQDMLNLEPVEAEKGIPPP---PPLLSGSLS
P-----PPPPPPPPLQSP-FP-----------------------------PAPPPPPAAP
LPHS-APDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

ALPTKRKTVKL---FWRELKLAGVRGGSG----------SRFGPSPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQP---------LLHHL
--------------S---------------------------------------------
------------DLYSEIPALARCAKVDFEQLTENLGQLERRSRAAEDSLRSLAKHELAP
ALRARLTHFLAHCTRRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTAE--------AAREVRIMQFCHTLREFALEYRTCWDRVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GENPSKPSVPMAVSSGL--GEGDADSHATMKSLLASKPEDAT
-HGRRSRGMVQSSSPVMPTA---VGPSTVPLEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------------------VSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQVMLFVDGMLGVVAHTETVQWLYMLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIYAVNSVASTTGALPWANLVCILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGAAGTDIDLRAQLVLYESALRMED
GDIEEA----AAGGRRERRKPSSEEGKRSRR------------SLEGGGCH-VRT-SEPG
-------TWGG------GMD------APGV------TC----------------------
------LLTD------PA-----------------SSPTGP------S----------SS
FSS------GPDPLT---------------------------SPVPSPMGPASG-LCTSA
NLFP-----ALSVASSADSSC-ERSIYKNPLP----------------------------
--------------------TCPSCSAP-----L---HGPSASSAQTRAFSLFLSR--LH
QTAPICL-----------------SPPLSFLSSCPPQPPPLPTVAGK----------ESL
IALPRSEWSRHH-----------NYYFFSHLPSP--TPTQGPSRTRGLSRPFSPR-----
-SLPPRLPLTRD-EDMDSQPGAHSPRHR--PGI---------------------------
----------------GQGGVEVEEQPRAKIRAGTEGQWRLEGPRKRHW-------IT--
HYFNIKGH-S----SQKLQTCQGRDVPIGTAIPFPCSKGPCLESGQTLSRTSLCTLTWEC
WVVSDPPQMWRIEQGLDMGGR---VLGLLGAWSVPVCLCVPA---IRGSAQGTSMCTTLG
WAAET-----------------------EKQAALAQGRAEALAGA-VPDEAD--GHPG--
ERVGGQNL---------------------PMSPCCPT-----------------------
-----------------EA------------MTLTAAS-----------LFLDARELW--
--SSPEPVPA-SVPKTPQSPAPRV--L----LRSQRSLEPEPKEPLAPPSPKAE------
---PTQKFSTHVPKLCIGDLDFSDLREDEDQDILNIETVEAGKGVPPPPPPLPLLSEGPP
P-----PPPPPPPPIKGP-------------------------------LPPPPPLPAAP
LPPS-APD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GLALPTKRKTVKL---FWRELKLAGGHGSSG----------SRFGPCSTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALVNF---DEFAVSKDGIEKLLTMMPTEEERQKIQEAQLANPDIPLAP---AETFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLYDLKVGMEQLVHNTTFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---MRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLAENLGQLEHRSRAAEESLRSLAKHELAP
ALRTRLTQFLAHCSRRVT------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFSLEYRTCRDRVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVGSGP--GQGDADSHASMKSLLTSKPEDAT
-HSRRSRGLVQSSSPV-PTA---VGASNAPPEESPGSSSPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

------------------------------------------------------------
--------------LEDCALQVSPSGYYLDPDLSLEEQREMLEDFYEEIGKGRKPTLILR
TQLSIRVHAIL--------EKL----YRSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQVMLFVDGMLGVVEHSETVQWLYTLCASMSRLV
VKTSLKLLLVFVEYAETNARLFIHAVNAVANATGASPWATFVSILEEKNGADSELLVFTM
TLINKTLAALPDQDSFYDVTDALEQQGMEGIVQKHLGSPGTDADLRVQLVLYESALRLED
GDPEEG----VPGVRRERRKPASEEGKRSRR------------SLEGAGPSNVSS-PKER
GER-EE---G--------------------------------------------------
------------------------------------------------------------
----------------------------SNGPS------LINGPDSSPVGPAPC-LSSSV
VLFP-----SPTVAPPTDALG-ERSIYKARFL----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ENVAAAETEKQAALAQGRAEALAGA-MPDESD--GHPG--
EQGTGDSR---------------------RSLVA--------------------------
------------------------------------P--------------RVSRGRW--
--EVTGG--------------------------------PRGEQGIAPPAPVGA------
---GPHRPGTGVG-GPVGRLQ----------AF-LPSPLRAGHSSGRGPGGPRVQSRGPR
AALWPGPAKATMAVRKRVQQPPPPELLPPGDGVTSKRPRQSQVGHLVRACEQ---VLAGE
V----TQHGSRS---PAEPGLEPGPWPQTQLEGGPGPPP--------TRGWLPPCP----
-----------------------ARPL

PF02181 // ENSGT00870000136417_3_Domain_0 (1528, 1850)

QKAAEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLGF---DEFAVSKDGIEKLLTMVPTEEERQKIQEAQSANPDIPLGP---AESFL
LTLAS-IGGLAARLQLWAFKLDYETMERDIAEPLFDLKQGMEQLVQNPTFRCILATLLAV
GNFLNNS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CTLVLQ---SQPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEVLAENLEQLERRSRAAAETAL---------
------------------------------------------------------------
------------------------------------------------------------
-------TLTEKFSSVA--ETSGLLPVPVAVGSGP--GQGDKDTDVTMRSLLSSGSEAPT
-HSRRSRGMAPSSST-----------AAAPPEEPPGSSSPPDASDEIMDRLVQSVTRSSP
R-ALAARERKRSRGNRKSLRRTLKGGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDEEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVANATGAPPWANLVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------SPAPLTG------------------------PTS---SPVGPPSG-LRASM
NLFP-----TISVAPSADTSS-ERSIYKQK------------------------------
------------------------------------------------------------
S---PWS----------------------------PLSHCPSA-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------L-------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAEA-MPSEAE--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPCV--L----LRAQRSLEPESKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEEEDQDMLNVESVEAGKEVPAPAPPLPLLSGVPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAP
ALRARLTHFLAQRARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGEEDCGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLST
QIAALHRLLGAPLKLEDCALQVSPSGYYLDLELSLEEQREMLESFYEEISKGRKPTVILR
TQLSVRVNTIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLNCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIQAVNSVASTTGALPWANLISILEEKNGADAELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLMLYERALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCF-VRA-PEPG
-------PIGP------ASS------IGPT------SST---------------------
------------------------------------------------------------
---------GLLP-S----------------------------PISSPVGLASG-LCTSA
NLFP-----TISLAPSIDSSG-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENM
AAAET-----------------------EKQAVLAQGRAETLAGAT-PDEAD--GP----
------------------------------------------------------------
---------------------------------------------------PGSRELW--
--GSPEPAS---APRTPQSTVPRI--L----LQAQQSLEPEHKEPLTPPSPKAE------
---PIPEIPTRVSKLCIGDLDFSDLGEDEDKDMLNVESVEAGKGIPHPPPLLPLQSAGPP
P-----PPPPLPL-------------------------------SIKGPCPPPPPLAAPP
-PRS-ALDGPL

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPTKRKTVKL---FWRELKLAGGHTGSA----------SRFGPSPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEKQKIQEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDE----IAEPLFDLKVGMEQLVQNTTFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRTAEESLRSLAKHELAP
ALRARLTHFLAQCSRRVA------MLKV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHILREFALEYRTCWERVLQHQKKRATYRERN
KTRGRMITETEKFSCVT-GEVSNNPSVPVAVGSGP--GQGDANSHASMKSLLTSRPENTT
-HGRRSRGMVQSSSPTVSTA---VGPSTALPDEPPGSSLPSDTSDEIMDLLVQSVTKNSP
R-ALAARERKRSRGNRKSLRRTLKNGLGDDLVQALGLSKTP---GLEV------------
---

-------MAGEEQRGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIQAVNAVASATGTLPWANLVSILEEKNGADAELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRFLGTAGTDVDLRTQLTLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------STGS------ASP------VGST------PST---------------------
------------------------------------------------------------
---------GSAPPTN------------------------S---AFSSTGPASGLLRTSV
NLFP-----TISVGPSVDSSC-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGAT-VDDTD--GS----
------------------------------------------------------------
---------------------------------------------------SGTRELW--
--DSPEPAS---APRTPQSPVSRI--L----LRTQRSLEPEPKKPVSPPSPKAE------
---PIQEPPTCVPKLCIGDLDFSDLGEDEDQDTLNVESVEAGKTSPFLSSLSPSLSGAPP
P-----PPPPPPPITGSCP----------------PPPPPPP-PPIIGSCPPP-PPLAAP
FTHS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

RHPTKRKTVKL---FWRELKLAGGPGCSR----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AARDVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNLSVPVAVGSGP--GRGDTDNHASMKSLLTSRPEDAT
-HSRRSRGMVQSSSPVSHTA---VGPSAASPEETAVSGSPTDTSDEIMDLLVQSVTKSGP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGGEDRGDEEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SFT------SPAPLTG------------------------PTS---SPVGPPSS-LRASV
NLFP-----TISVAPSADTSS-ERSIYKQK------------------------------
------------------------------------------------------------
S---PWS----------------------------PLSHCPSA-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------WPPSLR--------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAEA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETGP---APRTPQSPAPCV--L----LRAQRSLEPEPKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEEEDQDMLNVESVEAGKEVPAPAPPLPLLSGVPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLGGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
ITLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAP
ALRARLTHFLAQRARRVA------LLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGFYLDPELSLEEQREMLEGFYDEISKGRKPTLILR
TQLSVRVSAILXXXXXXXXXXX----XXXXXXXXXXXX-XX--XXXXXXXXXXXXXXXX-
--XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTLRLED
GDTEEAATCTASGGRRERRKPSSEEGKRSRR------------SLEGGGGP-VRT-PEPS
-------PAVPTSPRGPAS-----------------------------------------
------------------------------------------------------------
----------------------------------------PTGTASRPMSPPSN-PHASM
SFFP-----IIS----ADSSC-ERSVYXXXXXXXXXXXX-XXX-XXXX--XXXXXX----
--------------------------------------------------XXXXXX--X-
XXXX-XX---------------------------------------------------XX
------XXX-XX-----------XXXXXXXXXXX--XXX---------------------
--------X-XX-XXX-------XX-----------------------------------
-------------XXXXXXXXX----------------------XXXXX-------XXXX
XXXXXXXX-X----X--------------------------------XXXXX----X---
--XXX--XXXXX-------XX---X-------------------------------XXXX
XXXXX-----------------------XXXXXXXXXXXXXXXXXXXXXXXX--XX----
------------------------------------------------------------
---------------------------------------------------XXXXX----
--------X---------------------------------------------------
-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------
------------------------------------------------------------
-----XXXXXXXXXXXXXXXX---XXXXXXX--XX----------------X----XXXX
XXXXXXX-XXXXXXXXXXXXXXX

PF02181 // ENSGT00870000136417_3_Domain_0 (1524, 1960)

XXXXXKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLASPDIPLGP---AESFL
MTLAS-IGGLAARLQLWAFKLDYDGMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DFYSEIPALTRCAKVDFEQLDENLGQLERRSRAAEESLRGLAKHELAP
ALRNRLTHFLTQCARRVH------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQRKRATYRERN
KTRGRMITETEKFSGVA-GEVPSHPSVPVAVGSGP--GRGDADSHASMKSLLTSRPEDST
-HARRSRGMVQGSSPVMATA---PGPSTAPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGT---GLEV------------
---

-------MAGGEDRGDGEPLSVVTVRVQYLEDTDPFACANFPEPRRPPTCSLDGGLPLST
QIPALHRLLGAPLKLEDCALQVSPSGYYLDLELSLEEQREMLESFYEEISKGRKPTLILR
TQLSVRVSAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLNCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHNETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGAVPWANLMSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTSGTDVDLRTQLTLYESALRLED
GDMEEATAAVAAGGRRERRKPSSEEGKRSRR------------SLEGGGYL-VRA-QEPG
-------PIGP------ASM------TALT------SST---------------------
------------------------------------------------------------
---------DLAPPS----------------------------DVSSPVGLVSG-LYTSV
NLFP-----TISVAPSIESSG-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LERM
AAEET-----------------------EKQAALAQGRAETLARAT-PDEAD--GP----
------------------------------------------------------------
---------------------------------------------------PGLRELW--
--GSPEPAP---APRTPQSAVPRI--L----LQAQRSLEPEPKEPLAPLSPKAE------
---PIQEIPAWVSKLCIGDLDFSDLGEDEDQDILNVESVETGKGIPPPPPLLPLQSGGPP
P-----PPPPLPP-------------------------------PIKGFCPPPPPLVAPL
-PPS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

PLPTKRKTVKL---FWRELKIAGGHTGSG----------SHFGPSPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKTGESRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTAEEKQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDE----IAEPLFDLKVGMEQLVQNTTFHCILATLLAV
GNFLNGS------QSSGFELNYLEK--VSEV-------KDTVRRQS---------LLYHL
CCLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRTAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLKV-VHRRVSNR--------------------FHA
FLLYLGYPAQ--------TAREVRIMQFCHILREFALEYRTCRERVLQQQKKRATYRERN
KTRGRMITETEKFSGVA-GEVPNNPSVPVAVGSGP--GWGDADSHASMKSLLTSRPEDTT
-HGRRSRGMAQSSSPTVPTA---VGSSTALPDEPPGSSLPSDTSDEIMDLLVQSVTKNSP
R-AIAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKTP---GLEV------------
---

-------MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPAVHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YSSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGALPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GAGGRRERRKP--EEGKRSRR------------SLEGGGCP-ARA-PEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------GPALLTG------------------------PAS---SPVGPSFG-LQASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAGA-MPNEAA--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPSPCV--L----LRAQRSLEPEPKEPLIPASPKAE------
---PIWELPTRAPKLSIGDLDFSDLGEDEDQDMLNVESVEAGKEVPAPSPPLPLLSGVPP
P-----PPLPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-VPDSLAL

PF02181 // ENSGT00870000136417_3_Domain_0 (1453, 1959)

PTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MILAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNSS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRVAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDST
-HNRRSRGMVQSSSPIMPT----VGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALATRERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGSGREDGEA-AVVMVRVQYLEDADPFACANFPEPRRAPTCTLDGALPLGS
QIPALHRLLSAPLKXXXXXXXXXXXXXXXXXXXSLEEQREMLDDFYEEIGKGRKPTLILR
TQLSIRVHAIL--------EKL----YRSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQVMLFVDGMLGVVGHSETVQWLYTLCASVXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXLAPFLIQDSFYDVTDALEQQGMEALCRSTLGSSGTDADLRAQLVLYESALRLED
GDPEEG----VAGGRRERRKPSSEEGKRSRR------------SLEGXXXXXXXX-XXXX
------------------------------------------------------------
------------------------------------------------------------
----------------------------XTEPT------LTNSPDFSPIGPAPC-LSSSV
VLFP-----SPTVVPPTDALG-ERSIYKARFL----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ENVAAAETEKQAALAQGRAEALAGA-VLDEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDPRELW--
--STPEPAP---APQAPQSPLPRP--L----ILAQRILESEVLTP-----

PF02181 // ENSGT00870000136417_3_Domain_0 (1311, 1960)

-ETN------
---ITSEPLKRQPSLRIGDLDFSDLGEDEDQDLLATESTGAGXXXXXXXXXXXXXXXXXX
XXXXXX--------XXXX--------------------------------XX---X-XXX
-XXX-XXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXGPSPTLWA
SLEPVTL-DTAKLEHLFETRAKEVMSNKKAAEGRRTMTTVLDPKRSNAINIGLTALPPVH
VIKAALLGF---DEFAVSKDGIEXXXXXXXXXXXXXXXXXAQLANPDIPLGP---AESFL
LTLSS-IGGLAARLQLWAFKLDYETMEREIAEPLFDLKLGMEQLAQNPTFRCILATLLAV
GNFLNNS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CTLVLQ---SQPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEVLAENLGQLERRSWAAEENLKSLAKHDLTP
ALRARLTHFLSQCARRIA------MLKV-VHRRVCNR--------------------FHA
FLLYLGYPAE--------VAREVRVMQFCQTLREFALEYRTCRERVLQQQRKRATCRERN
KTRGRMITETEKFSSVAD----LSLPVPVAVGSGP--GQGDKDTDVXXXXXXXXXXXXXX
-XXXXXXXITPNNPP-AVA----PVTPATAPEETPSSGSPTDASDEIMDRLVQSVTRSSP
R-ALAARERKRSRGNRKSLRRTLKGGLGDDLVQALGLSKGP---SLEV------------
---

-------MAGEEDRGDGDPVSAVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLAAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQTYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASMSRLV
VKTALKLLLVFVEYSENNAPLLIHAVSSVASSTGCLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDTFYDVTDALEQQGMEALVQRHLGTSGTDVDLRTQLVLYENALRLED
GDIDEAA---A-GGRRERRKPSSEEGKRSRR------------SLEGGNCP-LRS-TEPG
-------PTGP------VSS------RAGP------------------------------
-----ASQTG------PT-----------------SSPSDL------ASTVT------ST
YST------GPALSTS------------------------LNS---SLMGPASG-LLTSV
NLFP-----AISVGPSADSSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAEA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDTRELW--
--GSPEPGP---APRTPQSPAPRS--L----LRAQRSLEPEPKEPLAPPSPKAE------
---PMQEFPIRVPKLCIGDLDFSDLGEDEDEDMLNMEAVEAGKGVPPPPPPLPVLSGGGL
P-----PPPPPPPPIKG-SLP-----------------------------PPPPP--TTP
LPPS-APDGLA

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPTKRKTVKL---FWRELKLAGGHEGSG----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRNLAKHELAP
ALRARLTHFLAQCGRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEVPSNPSVPVAVGSGP--GRGDADSHASMKSLLTSKPEDTT
-HGRRSRGMVQSTSPVMPTA---MGPSTAPPEEPPVSNLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLSA
QIAALHRLLGAPLKLEDCALQVSPSGYYLDLELSLEEQREMLESFYEEISKGRKPTVILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLNCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIQAVNSVASTTGTLPWANLMSILEQKNGADAELLVYTI
TLINKTLAALPDQDSFYDVTDALEQQGMEAMVQRHLGTAGTDVDLRTQLMLYESNLRLED
GDMEEAAAAATAGGRRERRKH-SEEGKRSRR------------SLEGGGYF-VRA-PEAG
-------PTGP------ASS------IDPT------SST---------------------
------------------------------------------------------------
---------GPALPS----------------------------PVSNPAGLASG-LYTSA
NLFP------ISLASSIDSSA-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENM
AAAET-----------------------EKQAALAQGRAEALAKGT-SDEAD--GS----
------------------------------------------------------------
---------------------------------------------------PGTQELW--
--DSPEPAS---APRTPQSTVSRL--L----LQPQQSLEPEHKEPLTPPSPKAE------
---PIQGISTRVSKLCIGDLDFSDLGEDEDQDLLNVESVEAGKGIPPPPPLLPLQCGGPP
P-----PPPPLPL-------------------------------SIKGPCPPPPPLAAPP
PPPS-TLDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

LHPTKKKTVKL---FWRELKLAGGHMGSG----------SHFGPSPTLWA
LLEPVSV-DKARLEHLFESRVKDVLPSKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEKQKIQEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNTTFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CCLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLSENLGQLERRSRTAEESLRSLAKHELAP
ALRARLTHFLAQCSRRVA------MLKV-VHRRVYNR--------------------FHG
FLLYLGYTAQ--------AAREVRIMQFCHILREFALEYRTCWERVLQQQKKRATYRERN
KTRGRMITETEKFSGVT-GEVPNNPSVPVAVGSGP--GQGDANSHASMKSLLTNRTEDTT
-HSRRSRGMVQSSSSTMPIT---VGPSTALPDETPGSSLPSDTSDEIMDLLVQSVTKNSP
R-ALATRERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKTP---GLEV------------
---

------------------------------------------------------------
------------------------------------------------------------
-------------------EKL----YSSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQVMLFVDGMLGVVGHSETVQWLYRLCESMSRLV
VKTALKLLLVFVEYAESNARLFIHAVSAVAIASGACPWANLVSILEEKNGADPELLVFAM
TLINKTLAALPDQDSFYDVTDALEQHGMEGIVQRHLGS-STDPDLRGQLVLYESALRLVD
GDPEEG----GVGGRRERRKPSTEEGKRIRR------------SLEP---------PRPR
SQYLRQAVSLPAACRRRLHSRDLWESLREE---RLQQGQ------------GMKGAEGPE
------WKG----------KVGDCKKTGRAGGGELSWGGPNWGPRE--------------
-----------VEMAAPQAPAPISISL-TVPSA------LSLPPALSASA-----PCFVL
LLFYRGCCPSPSLSPTAQRLS--------R------------------------------
---------L---------RTAP--------FWSFQSWGGAASPL----------FPFFH
TAEPSFH-----------------------------------------------------
-----------------------------SVPKSSLLLQLTRPAPWPPERPPAPRAQPVL
SRLDFAP----LHLTPSSFRGFLMTEGRFGRGLNPRQQVTRIAPPTALT-----LPVLGS
FRLCQHRVRQARE------G--LKERSESWSGNESKGEEKPRSSKGHGWL----------
-SAWIVACV-----RVSVCVCGTSSD-----LRVP--------------TSKMEKVQGVG
WGRHEAPDLK----SPARGTG---KWPCLPPFAASAS--------LTGSAE--------Q
RVLSIQARRQSCLSPRARFLENLAAAETEKQAALAQGRVEALAGA-LPDEPD--GHRASG
VWSSENVPRGCVWLP-P----H-HGD---SRATSAPWW-----------GEGVGASERGE
QGEEGE-----------VWWGGGSQ--GSAPRPLPSPC--L--------LLQSDRGSPPS
PSGALKLAPPHQPPCSPKRPGPLP--L----IRTRHSPEPEPPAPLARTCLTSEAELFRE
ATVSSARSATPSPTLCIGDLDFSDLGEDEDQGVLDREASERAAVGLV--VPPPLLGGVPP
---------PPPPPPGNFPPP--PPAPPPPLGV-----------------PPP-PP---P
-LGLFAPDG

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1926)

STLPTKRKTVKL---FWRELKLGPAGQGTTGGPAGM--GGGRFGPHSTLWA
ALEPVVV-DTARLEHLFESRAKEVLPPKRVSEGRKAVTTVLDPKRSNAINIGLTALPPPH
VIQTALLGF---DEFAVSKEGIEKLLTMLPTEEEKQKIQEAQLANPECPLGP---AESFL
LTLAS-IGGLAARLQLWAFKLDYEVMEREIAEPLFDLKVGMKQLVTNSTFRCILATLLAV
GNFLNGS------QTRGFELSYLEK--VSEV-------KDTVHRQS---------LLHHL
CALVLQ---SQPDAS---------------------------------------------
------------DLYSEIPALTRCAKVDFELLAENLAQLERRSLAAGDSLRSLAKHELAP
ALRTRLTMFLHNCDKRVA------TLKV-VHRRVCNR--------------------FQA
FLIYLGYP----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

-------MAGEEDRGDGEPLSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGALPWANLVSILEEKNGADPELLVYAV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENTLKLED
GDIEETA---AMGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRT-P--E
-------PRGP------TSP----------------------------------------
------------------------------------------------------------
--T------SPTQLTG------------------------PTT---SPVCPPSG-LSTSV
NLFP-----TISVASSADSSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAEA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDIRELW--
--DSPETAP---APRTPQSPVPRV--L----LRTQRSLEPEPKEPLTPPSPKAE------
---PIREIPSRVPRLCIGDLDFSDLGEDEDQDMLNMESVEAVEGVPPPPHTLPLLSGGPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPP--AAP
LPPS-ATDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

ALPTKRKTVKL---FWRELKLAGGCGGSG----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSNGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CTLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRGLAKHELSP
ALRARLTHFLAQCARRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAQEVRVMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEVPSNPSVPVAVGSGP--GRGDADSHASMKSLLTSKPEDTT
-HSRRSRGMAQSSSPVMPTV---VGPSTASSEESQGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEERGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLESFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGTLPWANLVSILEEKNGADPELLVYAV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLMLYESALRLED
GDTEEA---TAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------TESA------S-------------------MT---------------------
------------------------------------------------------------
---------PPTLLTS------------------------P---ASSHSGLASGT-RTSV
SLFP-----VISVAPSADSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
VAAET-----------------------EKQAALAQGRAEALAGAT-MDDTD--GL----
------------------------------------------------------------
---------------------------------------------------AGTRELW--
--DSPEPTS---APRTPQSPVSRI--L----LRTQRSLEPEPKEPLAPPSPKAE------
---PTLDLPPRVPKLCIGDLDFSDLGEDEDQDILSVESMESGKGISLSLLPPPLPSGGPP
P-----PPPPPPLVLGSCPP----------------PPPPPP-PPILGSCPPP-PPLAAP
LPPT-ALDGPA

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPAKRKTVKL---FWRELKLAGGPRRSG----------KHFGPSPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTMVLDPKRSNAINIGLTTLPPVH
VIKSALLNF---DEFAVSKDGIEKLLTMMPTDEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSRAAEDSLWSLAKHELPP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAQEVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRLITETEKFSGVA-GEAPSNLSIPMAVGSGP--GRGDADSHASMKSLLNSRTEDMT
-HGRRSRGMVQSSSPVSHTA---VEPSTAPPEETPGSNVPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGGDDRGDEGPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDQDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASATGAPPWANLVSILAEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GMGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------------S------------------------PTS---SPVGPPSG-LQASV
NLFP-----TISLAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------TR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGWAETLPGA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------LDARELW--
--DSPETAP---VPRTPHSPAPRV--L----LRTQRSLEPEPKEPLMPSSPKAE------
---PTWELPTRAPKLCIGDLDFSDLGEDEDQDMLNVESAEVGKGVPPPPPPLPLFSGVPP
P-----PPPLPPPSIKG-PFP-----------------------------PPPPL--AAT
LPPS-VPDSAA

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPTKRKTVKL---FWRELKLAAGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-ISGLAGRLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TQPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLKI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKNLLTSRSENTT
-HNRRSRGMVQSSSPIMPT----VGSSTASPEEPPGSSLPSDTSDEIMDMLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGS---GLEV------------
---

-------MAGGDDSGDGERVSVVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDQDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASATGAPPWANLVSILLEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GMGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------ST---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------------S------------------------PTS---SPMSPPSG-LQASV
NLFP-----TISLAPSADTSS-DRSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------TR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGWAETLAGA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------SDAQELW--
--DSPETAL---VPRTPHSPAPRV--L----LQTQRSLEPEPKEPLMSSSPKAE------
---PTWELPTRAPKLCIGDLDFSDLGEDEDQDMLNVESVEVGKGVPPPPPPLPLFSGVPP
P-----PPPLPPPPIKG-PFP-----------------------------PPPPL--AAT
LPPS-VPDSAA

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPTKRKTVKL---FWHELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-ISGLAGRLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TQPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTESLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLKI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPIMPT----VGPSAVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSGP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGS---GLEV------------
---

-------MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLNCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIQAVNSVASTAGTLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTAGTDVDLRTQLMLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGGS-VRA-PEPG
-------STGP------ASP------VGTT------SST---------------------
------------------------------------------------------------
---------GPASPAS------------------------P---VYSPPGPASGL-RTSV
NLFP-----TISVGPSVDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGAT-VDETD--GSS---
------------------------------------------------------------
--------------------------------------------------ASGTRELW--
--DSSEPAS---APRTPRSPVSRV--L----LRTQRSLEPEPKEPVSPPSPKAD------
---PIQELPTRVPKLCIGDLDFSDLGEDEDQDTLNMASVESEKTFPLLSHPPSSLAEGLP
P-----PPPPPPPILGSCPP----------------PPPPPP-PPIFGSCPPPPPPLAAP
LAHS-ALDGPI

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPTKRKTVKL---FWRELKPAAASGYSR----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDGMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSRAAEDSLRSLAKHELAP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAQEVRIMQFCHILREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNLSVPVAVGSGP--GRGDADSHASMKSLLTSRPEDTT
-HSRRSRGMVQSSSPVAHTV---VGPSTPSPEETSGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGGEDRGDREPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLYGALPLGV
QIPALHRLLGAPL-LEDCALQVSPSGYYLDPELSLKKQREMLEGFFEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGALPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYNVTDALDQQGMEALVQRHLGTAGTDVDLRAQLVLYENALRLED
GDMEEAF---AGGRRTTRRKPSSEEGKRSRR------------SLE------VRT-PEPS
-------TG-P------A------------------------------------------
------------------------------------------------------------
---------------------------------------------SSPGGQASG-LHTTV
SLFP-----TISVAPSSDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGA-MPEEVD--GH----
------------------------------------------------------------
---------------------------------------------------RDTLELR--
--GSPEPAP---APRTPQSAAPRI--L----LRAQQCLEPEPKETLAPPSPKTE------
---PIQELRTHVPKLCIGDLDFSDLGEDEDQDMLNTESVEAGKGVPPP---PPLISGGPP
P-----PPPPPPPPIKSP-FP-----------------------------P--PPPPVAP
LPPS-APD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GLALPTKRKTVKL---FWRELKLAGVHGGSG----------SRFGPCPTMWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DFYSEIPALTRCAKVDFEQLTENLGQLEHRCWAAEESLRNLAKHELAP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVYNR--------------------FHA
FLLYLGYTAE--------AAREVRIMQFCHTLREFALEYRTCRDRVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GETPSNSSVPVAVSSGP--GRGDADSHASMKSLLTSKPEDTT
-HGRRSRGMVQSSSPVMATA---VGPSTVPQEESLGSSLPSDTSDEIMDLLVQSVTKSNP
R-ALASRERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------MAGGEEHSDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDAELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGALPWANLVSILEEKNGADPELLVYTI
TLINKTLAALPDQDSFYDVTDALEQQGMETLVQRHLGTPGTDVDLRTQLMLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEAS
-------STGP------ASP------TGPI------S-T---------------------
------------------------------------------------------------
---------GPAPRTS------------------------P---TSSSASPA--SVITSV
NLFP-----SISMASSVDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAEALAGAM-VDEAD--GS----
------------------------------------------------------------
---------------------------------------------------SGTRELW--
--DSPEPAP---VPRTPQSPVSRI--L----LQAQRSLEPEITEPLIPSSPKAE------
---PIHDLPTRVPKLCIGDLDFSDLGEDEDQDMLNVEPVEAGKGIP---PPPPLISGGPP
P-----------------------------------PPPPPL-PPIKGPCPPP-PPLAAP
PPHS-ALDG

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

PAIPTKRKTVKL---FWRELKLAGGQGGSG----------SRFGPCSTLWA
SLEPVTV-DTARLEHLFESRAKDILPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALQNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDLPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDGMEREIAEPLFDLKVGMEQLVQNATFHCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVIQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSKAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAQEVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVGSGP--GRGDADSHASMKSLLISRPEDTT
-HNRRSRGMVQNSSPITHPA---VGSSTAPPEEPSGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALTARERKRSRGNRKSLRRTLKSGLGDELVQALGLSKAP---GLEV------------
---

------------------------------------------------------------
------------------------------------------------------------
AQQPVLMPLLA--------EKL----YNSQGPELRRSL-FS--LKQLFQEDKDLVPEFVN
LDGLTCLINVGAKADQNYQNYILRALSQIMLFMDGMQGVINHNETIQWLYTLSGSPFRLV
VKMALKLLLVFVEYTEPNALLLIRAVNAVDQARGVCPWSNLMAILEQRNGADTELLVFAM
TLINKTLAALPDQDSFYDVTDCLEQQGMERVVQQYLSSKGTDLDLKQQFVLYESALRLED
GVEEPP-----AGGRKERRK--TDEGRRGWR------------AQG--GCAELDSLQSPE
SPGSPS----DE------TLSTPKEPPIED------------------------------
-----------------------GPELS--------------------------------
---------------IPVEPCPKSVF--SSASSLRLSL----------------------
------------------------------------------------------------
------------------------------------------------------------
-PSPP-------------------------------------------------------
--------------------------------AE-----------------KEPP-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------SMGERSIYKARFLENLAAAQKEKMSAMAKGRIDILSDVAPL-E------HP-I
AWDGNSSNPDSGTEPPRMG---------------------------------SHAGR-QD
ISDSCSTISSDTKFMLDMLYAKGSSEPGRQKVFPEEPS----LSPHQGEVETDTGSSCAE
GPGGQEQESARPHGRAPEGLVASAHAK---LARAASSIDAESHTQKLENTV--MIPVKND
VELSWERLEAGPVQLKIKDLDFTDLGEEEDLDVLD--SGPIANGSFLPASI-EAASAGVP
------MAPPPPPVVPGCPPPPPP---PPMAPGCPPPPPPPP---MVPGCPPP-----PG
FSSPSATD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GPSQAKKKRTVKL---FWKELKQLDG--TVG---------SGRFG-QATLWA
SLQNVEV-NTAKLEHLFESRAKEMPASKKVTDGKK-VVVVLDPKRSNAINIGLTVLPPVH
IIKTAVLNF---DEFAVNKEGIEKILTMVPTEEEKQRIQEAQLANPDVPLGS---AEQFL
LSLSS-ISDLTARLQLWAFKLDYESLEQEIAEPLFDLKVGMEQLAKNHTFKCILATLLAM
GNFLNGS------QSRGFELGYLEK--VSEV--------------X---------LLHHL
CQMVVE---KFPETT---------------------------------------------
------------DLYSEIASITRSAKVDFDELANSLVQLERRCRASWDNLKVIAKHEAKP
VLKSKLTDFLKDSTQRIV------VLKV-VHRRVLNR--------------------FHS
FLLYLGYPAS--------VVRDVKVMPICKLLREFALEYRTCRERVLQQQKKRAAHRERN
KTRGRLITETEKFSGITE-----ASP-PAVVSTSPAQQEQAEVGHESMKSILSSPTDVPA
RRSRGGRVTGLATPSQG------------SPAQEDVPSSPDDASDEIMDRLVKSVTHSAN
PRPCPSRERRRSRGNRKSLRRTLKSGLSDELVQALGLGQAP---GMEV------------
---

-------MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYDEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIHVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTTLKLLLVFVEYSENNAPLFIQAVNSVASTTDTPPWANLVSILEEKNGADPELLVYTV
TLINKTLVALPDQDSFYDVTDALEQQGMEALVQRLLGTAGIDVDLRTQLMLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------PTGP------ASP------VDPT------LL----------------------
------------------------------------------------------------
--------------TS------------------------P---ASSPTGPAFGL-HTSV
NLFP-----TISVGPSMDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAEALAMAT-VDEID--GV----
------------------------------------------------------------
---------------------------------------------------TGTRELW--
--DSPEPDF---TPRTPQSPVPRI--L----LRTQRSLEPDCKEALA-PSPKAE------
---PIQELPTRVPKLCIGDLDFSDLGEDEDQDMLNVESVEIGREVLIPLPPPPLLSGGPP
P-----PPPPPPPILGSCPPP---------------PP----------------PPPVAP
IPHS-SPDG

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAESPGHSR----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDMLPSKKAGEGRRTITTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAHLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKMGMEQLVHNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELAP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAQEVRIMQFCHTMREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNLCVPVAVSSGP--GRGDADSHASMKNLLTIKPEDTT
-RNRRSRGMVQSSSPVTHTA---VGPSVVPPEETSGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALATRERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGGDDRGDGEPVPVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGFYLDPELSLEEQREMLEGFYEEISKGXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX----XXXXX------X-XX--XXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNAVACTTGTLPWANLMSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEVLVQRHLSTSGTDVDLRTQLVLYESALRLED
GDIEEAA--TASGGRRERRKPSSEEGKRSRR------------SLEGGGGCSVRP-PEPG
SIPTTTSP----------------------------------------------------
------------------------------------------------------------
--------------------------------T------SSPGPAMSPASPTSG-LRTSL
NLFP-----TLSVTPSTDSS--ERSIYKARFL----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ENVVAAETQKQAALAHGRAEALSEA-MPYEAD--GHSX--
XXXXX-------------------------------------------------------
------------------------------------------------------------
----XXXXXX-XXPRTPHSPTSRV--L----LRTQQSLESEPKVLLAPPSPKAE------
---SIHELPTHVSKLCIGDLDFSDLGEDEDQDMLNTDSIEAETGVPPPP---PLLSGQPP
P-----PPLPPPPSITGVIP------------------------------PPPPPPPVAP
LSHS-APD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GLALPTKRKTVKL---FWRELKLGGGHGGSR----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------XXXXXXXXXXXX
XXXXXXX--------XXXXXXXXXX--XXXX-------XXXXXXXX---------XXXXX
XXXXXX---XXXXXX--------------------------------------------X
XXXXXXXXXXXXXXXXXXXXXXXXXXVDFDQLSENLGQLERRSQAAKESLQGLAKHELVQ
TLRTRLTHFLTQCAHRVN------MLRI-VHRRICNR--------------------FHA
FLLYLGYSAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQKKRATCRERN
KTRGRMITETEKFSGVT-GETPSNPSVPVAVGSGP--GRGDADSHTSMKNLLTSKSEDTT
-HPRRSRGMVQSSSPTMPQT---MGPATAPPEEPQGSSLPSDTSDEIMDLLVQSVTKSNP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKTP---GLEV------------
---

-------MAGEEDRGDVEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSCGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLLIYAVNSVASNTGALPWANMVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTPGTDVDLRAQLVLYESALRLED
GDIEEAA---A-RGRRERRKPSSEDGKRSRR------------SLESGGCP-VRA-TEPG
-------PMGP------A------------------------------------------
------------------------------------------------------------
----------------------------------------------------PG-LRTSM
NLFP-----TISAMPSADSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGA-MLDEPD--GH----
------------------------------------------------------------
---------------------------------------------------PDIQELW--
--GSPEPVP---APRTPQSPGPRV--L----LRAQQSLEPEPKEPLTLPSPKAE------
---PIKELPTRVPKLCIGDLDFSDLGEDEDQDMLNMESVEAVKGVPPPPPPLPLLSGGPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPP--AAP
LPPS-ALD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GLALPTKRKTVKL---FWRELKLAGSHAGSR----------SRFGPCSTLWA
CLEPVSV-DTARLEHLFESRAKDILPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
ITLAS-IGGLTARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFELLTENLGQLERRSGAAEESLRNLAKHELAP
ALRARLTHFLAQCARRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GETPSNPSVPVAVGSGP--GRGDVDSHASMKSLLTSKPEDTT
-HSRRSRGLVQSSSPVIPIA---VGPSTAPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------MAGGEDREDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------PTSP------TGP------ALP-------------------------------
--------------------------------------------------TG------PT
SST------SPAPLTG------------------------PTS---SPVGPPSG-LRASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------A----------------------------PESPPVPQ-----------------
----------------------------------------SPP-----------------
------------------------------------------------------------
----------------GQASLE--------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAGA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPCV--L----LRAQRSLEPEPKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEDEDQDMLNAESVEAGKEVPAPAPPLPLLSGVPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTGEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAP
ALRARLTHFLAQRARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQASPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIQAVNAVANATGTLPWANLVSILEEKNGADAELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRFLGTAGTDVDLRTQLTLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRT-PESG
-------STGS------ASP------VGST------PST---------------------
------------------------------------------------------------
---------GSATPTS------------------------P---AFCPASPASGL-RTSV
NLFP-----TISVGPSVDSSC-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGAT-VDDTD--GS----
------------------------------------------------------------
---------------------------------------------------SGTRELW--
--DSPEPAS---VPRTPQSPVPRI--L----LRTQRSHEPEPKKPVSPPSPKAE------
---PIQEPPTRVPKLCIGDLDFSDLGEDEDQDTLNVDSVEAGKASPFLSPLSPA------
------------------------------TSSCPPPPPPPP-PPIIDSCPPP-PPLAVP
FNHS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

RHPTKRKTVKL---FWRELKLPGGPGGSR----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSRSAEDSLRSLAKHELSP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AARDVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNLSVPVAVGSGP--GRGDADNHASMKSLLTSRPEDAT
-HSRRSRGMVQSSSPVSHTA---VGPSAASPEETAASGLPTDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIQAVNAVASNTGTLPWANLVSILEEKNGVDPELLVYTV
TLINKTLAALPDQDSFYDVTDAFEQQGMEALVQRLLGTAGTDVDLRTQLTLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRT-PEPG
-------PTGS------ASP------VGSA------SFT---------------------
------------------------------------------------------------
---------DSTSPTS------------------------S---AFSPTGPASGL-HTSV
NLFP-----TISVGPSVDTSC-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGAT-VDETD--ES----
------------------------------------------------------------
---------------------------------------------------SGTRELW--
--DSSEPAS---APRPPQSPVSPI--V----LRTQRSLEPEPKEPVSPRSPKTE------
---PVQELPTHVPKLCIGDLDFSDLGEDEDQDTLNVESVEAGKASLVLSL----------
---------------------------------PPPPPPPPP-PPIMGSCLPP-PPLAAP
FPHS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

RHPTKRKTVKL---FWRELKPTGSPGCSR----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTIVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEVPSNLSVPVAVGSGP--GRGDADNHASMKSLLTSRPEDAT
-HSRRSRGMVQSSSPVTHTT---VGPFTASPEETAASGLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

--------------------ATVPCRVQYLEDADPFAFGSFPEPRRAPVYALEEALALGA
QLPALHRLVGAPLPLEDCTLQVSPSGHYLDLDLSLLEQKDDLEGFYEEVRKGRRPTLILR
TQLSVRVHAII--------EKL----YNSQGPELRRSL-FS--LKQLFQEDKDLVPEFVN
LEGLTCLIKVGAEADQNYQNYILRALSQIMLFVDGMQGVINHNETVQWLYTLSGSPFRLV
VKTALKLLLVFVEYTEPNALLLIRAVNAVDQARGACPWSNLMAILEQRNGADTELLVFTM
TLINKTLAALPDQDTFYDVTDCLEQQGMEQVVQQYLGSKGTDLDLKQQFTLYESALKLED
DVEEPP-----SGGRKERRR--TDEGRRGRR------------SQG--GSQDSSADA---
---QPL----LE------SPGTPKEPPAED------------------------------
-----------------------TLPIPAPSSPADSTCIHCWCQGGEQSC-G--------
--------TCSQSLSSSSRPCPTSIY--NSTSSVRLALAPPLLRRSSPRAQESA-ACTSK
EPGGAGG---------------------------------MESGRALELDRCMVGQQVSK
VQPGAPRHPSGMHSSAPAPPHSPLCPRL--P--SPLPTLSVFP-FA--------GCTK-L
----PLSGDGQCPISPAP------------------------------------------
-------------------------------DAT-----------------HEPQGT---
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------ASRPEEQEHALNAGD
F------------------------------------------CA---------------
--------------------VGLAVQCGEKISSMAKGRLDVLSDTTLEHP------TA-L
AWERDHGTSDSGMEPPSITHPTAEQDSSSTLSPAPPGPSKQIVPASPSFPAGSHLAR-SD
ITDSCSTISSDTKFMLDMLYAKGSSESGREKTFHERPL----SPQIQGEVEMDA-----K
GSSSQEQESPRLRGRAPDGPVASAHAK---LVRAMSSIDDETHTQKLENTG--MMPIKKD
TELTWERLETIPVQLKIKDLDFTDLGEEEDFDILD--TGPMTNG------------AGTF
------MAPPPPPALPGCPPPPPP---PPAIPGCPPPPP--P---ALPGCPPPPPPELPG
LPGPSTTDG

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

PSQAKKKRTVKL---FWKELKQLDG--TVE---------PGRFG-QGTLWA
SLQNVEV-NTAKLEHLFESRSKEAPTSKKAIDGKK-VVVVLDPKRSNAINIGLTVLPPIH
IIKTAVLNF---DEFAVSKEGIEKILTMVPTEEEKQKIQEAQLANPDVPLGS---AEQFL
LSLSS-ISDLTARLQLWAFKLDYESLEQEIAEPLFDLKVGMEQLARNHTFKCILATLLAT
GNFLNGS------QSRGFELSYLEK--VSEV-------KDTVHRQS---------LLYHL
CQMVVE---KFPETT---------------------------------------------
------------DLYSEIASITRSAKVDFEELANSLVQLERRCRASWHNLKVIAKHETKP
VLKTKLTEFLKDSTQRII------VLKIVVHRRVLNR--------------------FHS
FLLYLGYPAS--------VAREVKVTSICKLLQEFALEYRTCRERVLLQQKKRAAHRERS
KTRGRLITETEKFSGIAE-----AVLPPAMVSSSP--KEQMEAGHESMKILLTSPTDLPA
RRSRASQGTGHGTPTQT------------SPAQEDVPSSPDDASDEIMDQLVKSVTHNPN
PRPCPNKERRRSRVNRKSLRRTLKSGLSDDLVQALGL-----------------------
---

-------MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDSELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIQAVNSVASATGALPWANLVTILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDMTDALEQQGMEALVQRHLGTAGTDVDLRTQLMLYESALRLED
GDLEEAAATAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------PTGS------AS-----------------------------------------
-------------------------------------------------PIG------SA
SST------SPAQLIS------------------------PAS---SPVGLASG-LGTLV
NLFP-----AISVAPSAGNSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LEGV
AAAET-----------------------EKQAALAQGRAETLAGA-TPDEAD--GP----
------------------------------------------------------------
---------------------------------------------------PGIRELW--
--DSSEPIP---APRTPQSPVPRV--L----LQAQRSLELEPKEPLVPPSPKAE------
---PIQELPTRTPKLCIGDLDFSDLGEDEDQDILNVESVEAGKGAPPPPPPLPLHSGGSP
P-----PPPPLPLYSGGPPHP-----------------------------PPPPPSFCPP
LPRS-APDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

ALPTKRKTVKL---FWRELKLAGDHGKSG----------SRFGPCTTLWA
SLEPITV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKMGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TLPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEENLRSLAKHELAP
ALRARLTHFLAHCARRVA------TLRV-VHRRVNNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQKKRATYRERN
KTRGRMITETEKFSGVA-GETPNNPPVPMAVGSGP--GQGDADSHASMKSLLTSRPEDTT
-HSRRSRGIVQSSSPVMPPA---VGPSTAPSEESPGSSLPSDTSDEIMDLLVQSVTKSNP
R-AATARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKTP---GLEV------------
---

MPPPELRARCGGGGGAAMAEAAVPCRVQYLEDSDPFGCGSFPEPRRAPVYAVEEALALGA
QLPAVHRLLGAPLPLEDCTLQVSPSGHYLDLELSLLEQKDDLEAFYEEVRKGRRPTLILR
TQLSVRVHAII--------EKL----YNSQGPELRRSL-FS--LKQLFQEDKDLVPEFVN
LDGLTCLINVGAEADQNYQNYILRALSQIMLFVDGMQGVINHNETVQWLYTLSGSPFRLV
VKMALKLLLVFVEYTEPNALLLIRAVNAVDQARGACPWSNLMAILEQRNGADTELLVFAM
TLINKTLAALPDQDSFYDVTDCLEQQGMERVVQQYLSSKGTDLDLKQQFVLYESALRLED
GVEEPP-----AGGRKERRK--TDEGRRGWR------------AQG--SCAEPDPLQSPG
SPASPN-----E------TPSTPKEPPIED------------------------------
-----------------------SPELS--------------------------------
---------------IPVEPCPKSIL--SSASSLRLSL----------------------
------------------------------------------------------------
------------------------------------------------------------
-SSPP-------------------------------------------------------
--------------------------------AE-----------------KEPP-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------SVGERSVYKARFLENLAAAQKEKMSAMAKGRIDILSDVAPL-E------HP-V
TWDGDGSNPDAGTEPPRMR---------------------------------SHAGR-QD
VFDSCSTIS-DTKFMLDMLYAKGSSEPGRQKVFPEEPS----LSPHHGEVETDAGSSCAE
GPGGQEQESARPHGRAPDGLVASAHAK---LARAASSIDAESHTQKLENTV--MMPVKND
VELSWERLEAGPVQLKIKDLDFTDLGEEEDLDVLD--SGPIANGSFLPGSI-EAASAGVL
------MAPPPLPMVPGCPPPPPP---PPVVPGCPPPPPPPP---MVPGCPPP-----PG
FSGPSAMDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

SQAKKKRTVKL---FWKELKQLDG--TVG---------SGRFG-QATLWA
SLQNVEV-NTAKLEHLFESRAKEMPASKKVTDGKK-VVVVLDPKRSNAINIGLTVLPPVH
IIKTAVLNF---DEFAVSKEGIEKILTMVPTEEEKQKIQEAQLANPDVPLGS---AEQFL
LSLSS-ISDLTARLQLWAFKLDYESLEQEIAEPLFDLKVGMEQLARNHTFKCILATLLAM
GNFLNGS------QSRGFELGYLEK--VSEV-------KDTVHRQS---------LLHHL
CQMVVE---KFPETT---------------------------------------------
------------DLYSEIASITRSAKVDFDELANSLVQLERRCRASWDNLKVIAKHEAKP
VLKSKLTDFLKDSTQRIV------VLKV-VHRRVLNR--------------------FHS
FLLYLGYPAS--------AARDVKVMPICKLLREFALEYRTCRERVLQQQKKRAAHRERN
KTRGRLITETEKFSGITE-----ASP-PAVVSASPTQQEQAEVGHESMKSVLSSPTDVPA
RRSRGGRGTGLTTPSQG------------SPAQEDVPSSPDDASDEIMDRLVKSVTHSAN
PRPCPSRERRRSRGNRKSLRRTLKSGLSDELVQALGLGRAP---GMEV------------
---

------------------------------------------------------------
----------------------------------------MLEGFFEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGTLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLSTAGTDVDLRAQLVLYESALRLED
GDMEEAM---AGGRRTTRRKPSSEEGKRSRR------------SLE------VRS-PEPG
-------STGP------ASP------VVST------SSS---------------------
------------------------------------------------------------
---------TDPASSP------------------------VG--PAPATGPASS-SHTSV
SLFP-----TISVAPSSDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AVTET-----------------------AKQAALAQGRAETLAEA-MPDDVD--GH----
------------------------------------------------------------
---------------------------------------------------PDTQEQR--
--GSPEPVP---TPRTPQNAAPRI--L----LQAQQSLEPEPKEPLVPPSPKPE------
---PIQELPTRGPRLCIGDLDFSDLGEDEDRDMLNIESVEAGNGVPPPPPPLPLLSGSPP
P-----PPPPPPPLNKSP-FP-----------------------------P--PPPPAAP
LPPS-APDGLA

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPTKRKTVKL---FWRELKLAGVHGGSS----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSRGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---IRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAHCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAE--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GETPSHPSVPVAVSSGP--GRGDADSHASMKSLLASKPEDAT
-HGRRSRGNVQNSSPVMPTT---VGPSTVPPEEPPGSTLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

------------------------------------------------------------
-------------QLEDCTLQISPSGHYLDLDLSLLEQKDDLEGFYEEVRKGRRPTLILR
TQLSVRVHAII--------DLL----YNSQGPELRRSL-FS--LKQLFQEDKDLVPEFVN
LDGLTCLIKVGAEADQNYQNYILRALSQIMLFVDGMLGVINHNETVQWLYTLSGSLFRLV
VKMALKLLLVFVEYTEPNALLLIRAVNAVDQARGVCPWSNLMAILQQRNGADTELLVFAM
TLINKTLAALPDQDSFYDVTDCLEQQGMETVVQQYLSSKGTDLDLKQQFVLYESALKLED
GVEDH------RGGRKERRK--TDEGRRGWR------------AQG--SCAEPCADX---
----------PG------TPSTPKEPPVED------------------------------
-----------------------SPELSIPADAGMRE--------GESPP----------
--------RSPSVPPLSPGHAQRAPT--TARPACGCLCRAPRLRRSSPRALGRG-ACTSK
QPGGDGA---LGMEDAQARRGQSEVAQPGLS-----------------------------
------Q-----HHLAPL-GHARLFSSS--I----SSPLLLFS-GHADSLLCPLFLSFLL
QAAP------TCPCLV--------------------------------------------
----------------------SAQALHACDASR-----------------RTPL-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-A------------------------VPSPCISS---ACV---LAGWPGPPCHRGPTRGG
---SALQTPLMVLPLGGTA-LELASSTRTSLVALMMGTVPP---RRQHHAAPRQGCRN-L
ALGGRGAGGGSSCVPSSTV---------------VPSWVVVNTSLGPKSDGGSHAGR-QD
TTDSCSAISSDTKFMLDMLYAKGSSELGRQKVFPEGLSSSLSSSQYHGEEEMSTRQGSAE
GHGGREPESTWLHGRAPDGPVASAHAK---LARAASNIDAETHTQKLENTM--MMPIKKD
TELSWEHLQASPAQLKIKDLDFTDLGEEEDFDILDTDTGPIANGSFLPPGI-QAASAGVL
------MAPPPPWTL---------------------------------------------
----AATD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GPSQAKKKRTVKL---FWKELKQLDG--SVG---------PGRFG-RATLWA
SLQSVEV-NTAKLEHLFESRAKEVPASKKATDGKK-VVVVLDPKRSNAINIGLTVLPPVH
IIKTAVLNF---DEFAVNKEGIEKILTMVPTEEEKQKIQEAQLANPDVPLGS---AEQFL
LSLSS-ISDLTARLQLWAFKLDYESLEQEIAEPLFDLKVGMEQLAKNHTFKCILATLLAM
GNFLNGS------QSRGFELGYLEK--VSEV-------KDTVHRQS---------LLHHL
CQMVVE---KFPETT---------------------------------------------
------------DLYSEIASITRSAKVDFDELANSLVQLERRCRASWDNLKVIAKHETKP
VLKSKLTDFLKDSTQRIV------VLKV-VHRRVLNR--------------------FHS
FLLYLGYPAS--------AVRDVKVMPICKLLREFALEYRTCRERVLQQQKKRAAHRERN
KTRGRLITETEKFSGIAE-----ATVPPAVVSASPKQQEQAEEGHENMKSVLSLPTDVPA
RRSRPSRGRSG-----L------------GMGQEDVPSSPDDASDEIMDRLVKSVTQSAN
PRPCANKERRRSRGNRKSLRRTLKSGLSDDLVQALGLGRAP---SMEV------------
---

-------MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPAVHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YSSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-PEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------GPALLTG------------------------PAS---SPVGPPSG-LQASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------A----------------------------PESPPVPQ-----------------
----------------------------------------SPP-----------------
------------------------------------------------------------
----------------GQARLE--------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAGA-MPNEAG--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAS---AARTPQSPAPCV--L----LRAQQSFAPEPKEPLIPASPKAE------
---PIWELPTRVPKLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPP
P-----PPLPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-VPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPIMPT----VGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGRDDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDQDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASATGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLAVLPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GMGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------------S------------------------PTS---SPVGPPSG-LQASV
NLFP-----TISLAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVVLAQGWAETLAGA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------SDARELW--
--DSPETAP---IPRTPHSPAPRV--L----LRTQRSLEPEPKEPLMPSSPKAE------
---PTWELPTRAPKLCIGDLDFSDLGEDEDQDMLNVESVEVGKGVPPPPPPLPLFSGVPP
P-----PPPLPPPPIKG-PFP-----------------------------PPPPL--AAT
LPSS-VPDSAA

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-ISGLAGRLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TQPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEDSLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLKI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRTEDTT
-HNRRSRGMVQSSSPIMPT----VGPSTAPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGS---GLEV------------
---

-------MAGGE--------DLVTVRVQYLEDTDPFACANFPEPRRPPTCSLDGGLPLST
QIPALHRLLGAPLKLEDCALQVSPSGYYVDLELSLEEQREMLESFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLNCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHNETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGTLPWANMMSILEEKNGADPELLVYTV
TLINKTLGALPDQDSFYDMTDALEQQGMEALVQRLLGTAGTDVDLRTQLMLYESALRLED
GDMEEATAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGYL-VRA-PEPG
-------PTGP------SST------IGLT------SCT---------------------
------------------------------------------------------------
---------DLAPPS----------------------------AVSSPAGLASG-PYTSV
NLFP-----TISVAPSIDSSG-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LEHM
AAAET-----------------------EKQAALAQGRAETLARAT-PDEAD--GP----
------------------------------------------------------------
---------------------------------------------------PGTQELW--
--GSPEPAP---APRTPQSAAPRI--L----LRAQGSLEPETKEPPAPLSPKDE------
---PIQEIPGRVSKLCIGDLDFSDLGEDEDQDILNVESVEAGKGIPLPPPLLPLQSGGPP
P-----PPPPLPP-------------------------------PIKGPCPPPPPLAAPL
-PPS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

PLPTKRKTVKL---FWRELKLAGCHTGSR----------SHFGPSPTLWA
SLDPVSV-DTARLEHLFESRAKDVLPSKKTGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEKQKIEEAQLANPDVPLGP---AENFL
MTLAS-TGGLASRLQLWAFKLDYDSMEREIAEPLFDLKVGMGQLVQNTTFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CCLVLQ---TQPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRTAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLEV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------TAREVRIMQFCHILREFALEYRTCRERVLQQQKKRATYRERN
KTRGRMITETEKFSGVA-GEVPNNPSVPVAVGSGP--GRGDADSHASMKSLLTSRPEDTT
-HVRRSRGMVQSSSPIMPTA---VGPSTTLPDEPPGSSLPSDTSDEIMDLLVQSVTKNSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKTP---GLEV------------
---

-------------------VSVLTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLAAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLPVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASVSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASSTGSLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGASGTDFDLRTQLVLYENALRLED
GDIEEA----AAGGRRERRKPSSEAGAALYTPRSLGKRELAFRTWGGVLCP-ASP-TGPA
SPTGPASPTGPASPTGPASPTGPASPTGPASPTGPASPTGPASPTGPASPTGPASPTGPA
SPTGPASPTGPASPTGPASPTGPASPTGPASPTGPASPTGPASPTGPASPTGPASPTGPA
SPTGPASPTGPASPTGPADPASTVISTYSAGPA------LSTGLAPSPVGPASG-LCTSV
NLFP-----AISVGSSADSSS-ERSIYKRLPLESSLQLS-LHS-EPLH--RPSASSAQTP
LPKRVLSLSF---------QTSPNCSCL-----VSDCWGVEFCSDWTSSSCCFVFISFWH
SACP-CPSPSLCLTAPCPASRQSLPSISSFLMSCL-----------------------LH
TSSPHWGWEGTPGITAELCGGTSSWALEWSRHHNYHLFL-LSPPPRAPESPPVPQSPTEQ
ARLEN--------EDTDSQPGAHSP-----------------------------------
-------RNRAEGLSRVLYSVGVEEQPRTEGSAGTEGQQRLEGLKKKKK-------TGLH
SLFQHKNQDS----E--------------------------------HEQQQN-------
---ST--------------------------------------------PPSRARFLENV
AA-----------------------AETEKQAALAQGRAETLAGAM--------------
------------------------------------------------------------
---------------------------------------------------PDTRELW--
--GSPEPGP---APRTPESPVPRG--L----LRAQRSLEPEPKVPLAPPSPKAE------
---PIQEFPIRVPKLCIGDLDFSDLGEDEDEDMLNVEAVEAGKAPPP-------------
-------------PIKGS--------------------------------LSPPPPPAAP
LSPS-APD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GLALPTKRKTVKL---FWRELKLAGGQ----------------RGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVKNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSWAAEESLRSLAKHELPP
ALRARLTHFLAQCGRRVA------MLRV-VHRRVYNR--------------------FRA
FLLYLGYTAP--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATCRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVGGGP--GRGDADSHASMKSLLTSKPEDTT
-HGRRSRGMVQSSSPVMATA---MGPSTASPEDPPGSSIPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

------------------------------------------------------------
------------LQLEDCTLQLSPSGQYLDLDLSLLEQKDELEGFYEEISKGRRPTIILR
TQLSVRVNAIL--------GEA----GNYGGPLLHSPL-FS--GKQWTQEDKDLVPEFVN
SEGLTCLIKVGAEADQNYQHYILRALSQIMLFVDGMLGVIEHNETVQWFYTLCGSMYRLV
VKTALKLLLVFVEYTEANAQLLIQAVNTVDQAQGACPWANLVAILDERNGADTELLVFAM
MLINKPGAAVER----AGLTACLEQQGMEGIVQRHTQGKGLDPDLKQQFAIYEVSALASR
APPPPP-----PGGGRCQSR--DPS-LPPAH------------CSA--GCAPGQ-RRRAG
EP-ALL----PD------SPRSPRPPPTGT------------------------------
-----------------------CVDLHVPHPPE------LWLQQRS-------------
-------------------------------PVT---------------------SCRSR
P-------------------------CDRRGT--AEV-----------------------
------------------------------------------------------------
------EGGGPAPSRA--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LPLAGWGAAMR--------
----------------------------EKGRAQSRGGRHQYSHTGM------------L
A-RGQ-AAAGASSIPSAGV------------STRRSRW--------------PSSPP-QE
SADPCSSISSDEGLTRDALCAKSRAEPARDPACQP-------------------------
--ELQGLESTRPRGKAPAGQVSVR---------PQARVEAEASAPSGERAL--LTPFRKD
AEFPWDRLESGPLLLKVKDLDFSDLGEEEDFDALE--QGPFFKGGTIPPQGGEEGGVRMS
------PLPRPRWPLPCCGGGAES---PRGLQGMPAA---PA---VLEGCAAS-----RG
STGPESITSPAGLTKGSRCPG---SWVQGKVARGACLLS---------QRRFS-QQISWR
RAPGRVR-GSPHAPHL---PFSPFPS

PF02181 // ENSGT00870000136417_3_Domain_0 (1527, 1827)

FQKAADGKK-CTEVLDPKRSNAINIGLTVLPPAH
VIKTAILNF---DEFAISKEGIEKILTMVPTEEEKQKIQEAQLANPDVPLGS---AEQFL
LTLAS-INELTAAGRP--LTAAAPSPTQEIAEPLFDLKLGMDQLAQNQTFRCILATLLAM
GNFLNGS------QSRGFELSYLEK--VSEV-------KDTVHRQS---------LLHHL
CHAVVE---RFPQSS---------------------------------------------
------------DLYSEIAAITRSAKV---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

-------MAGEEERGEGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
IKTALKLLLVFVEYSENNAPLFIQAVNSVASTTGTLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTAGTDVDLRTQLMLYESALRFED
GDMEEAATAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRT-PEPG
-------STGP------ASP------SGSA------SFT---------------------
------------------------------------------------------------
---------GPTSLAS------------------------P---GVSPTDPASGL-RTSV
NLFP-----TISVGPSVDSSC-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGVT-VDETD--GAS---
------------------------------------------------------------
--------------------------------------------------SSGTRELW--
--DSPEPAS---TPRTPQSPVSRI--L----LRTQLSLEPEPKESLSPPSPKAE------
---PVHELPARVHKLCIGDLDFSDLGEDEDQDTLNVASVESEKTFPLISHPPSSISGGPP
P-----PPPPPPPILGSCPP----------------PPPPPP-PPILGSCPPP-PPLAAP
FPHS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

SLPTKRKTVKL---FWRELKLAGGPGYSR----------SHFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTIVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLASPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS-----FQSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELAS
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSSLSVPVAVGSGP--GRGDADSHATMKSLLTSRPEDTV
-HSRRSRGMVQSSSPATHTA---VGPSTVSPEETSGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGGEDRGDGEPISVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPAVHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YSSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-PEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------GPALLTG------------------------PTS---SPVGPPSG-LQASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAGA-MPNEAG--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---AARTPQSPAPCV--L----LRAQRSLAPEPKEPLIPASPKAE------
---PIWELPTRAPKLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPP
P-----PPLPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-VPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPIMPT----VGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MAGE------ED-----------------RGDGEP------VS-----------
------------------------------------------------------------
-----------------------VVTVR--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------VQ---Y-------------------------------LEDT
DPFAC-----------------------ANFPEPRRAPTCSLDGALPLDEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDTHELW--
--GSPDTAP---APKTPQSPVPRV--L----LRAQRSLELEPKEPLTPPSPKAE------
---PILVLPSRVPRLCIGDLDFSDLGEDEDQDMLNMEPVEAGQGIPPPPPPLPLLSGGPP
P-----PPPPPLPPIKG-PFP-----------------------------PPPPL--AAP
LPPS-APDG

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

PVIPTKRKTVKL---FWRELKLAGGRGGSG----------SHFGPCPTLWA
SLESVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMQQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRGLAKHELAP
ALRARLTHFLAQCARRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRIMQFCNTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVGSGP--GQGDADNHASMKSLLTSKPEDTT
-HSRRSRGMAQSSSPVTPTA---GSPSTASPEPQ----GSSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSSPQNLSSRILALE----LCVQGP---SLEQ------------
---

-------------------VSLVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFFEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLTRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHTETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQHHLGKAGTDVDLRAQLVLYENALRLED
GDLEEAV---TGGRRTTRRKPSSEEGKRSRR------------SLE------VRS-PEPG
-------STGP------ASP------VVST------SAA------SP-------------
-----VLPTS------PT-----------------S------------------------
---------CPVGPAS------------------------PPSPASSPVGPASG-LHSTL
RLFP-----SVSVAPSSDSSL-SREIEAVVGDFSPSVPP-LC---ALP--RALRLLCPNF
SAKRVLSLSF---------QTSPNCSCL-----VSDCWGVGFGSDWTSSFCGFSSS--LS
GIPPVLSMSSVS-LPPSVSVSLSLSVTLSFRCLCLLLHPVLRHVRLSSPFPVSSHHASPT
PSYSHCDWEGTPDITARLCVGVSNWALWGGAGTTVTISSSHPPRPRAPESPPVPQVPTGE
ARLEPAMCS-GL-QHCFPQRGFHVPDATRAGGLSQTYASSD-------------------
-------------TQEVLRSAEVEEQPLSKGRTETECQQRLEGPKETG------------
-------S-P----LGSCQTCQGRDSLNQNSEHE-------------HEQQQDCKLD---
--VTMGTGLWQI-------------LVCSAHGRFPVCLCVPA---SRGSAQGPSKACAPP
WAGVCQTPSLTSSSPQSPVPGECSSSRNRKAGCAGQGRAETLAGA-MPDDMD--GCPG--
EWVGGQYP---------------------PTLPCCSR-----------------------
-----------------ED------------MTLTAAS-----------LCLDTRE----
------------------------------------------------------------
-------------------SRYSXLGEDEDQDMLNMESVEAEKGIPPPPPPPPLLSGSLP
P-----PPPPPPPPLKSP-FP-----------------------------PTPPPPPAAP
LPHS-APDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

ALPTKRKTVKL---FWRELKLAGVRGGSG----------SRFGPSPTLWA
SLEPVSV-DTARLEHLFESRAKDMLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQP---------LLHHL
CALVLQ---ARPDSS---------------------------------------------
------------DLYSEIPALARCAKVDFEQLTENLGQLERRSRAAEDSLRSLTKHDLAP
ALRARLTHFLVHCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAE--------AAREVRIMQFCHTLREFALEYRTCRDRVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GETPSKPSVPVAVSSGP--GEGDADSHATMKSLLASKPEDAT
-HGRRSRGGTSG-----CWA---VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------MAGGEDSGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLST
QIAALHRLLGAPLKLEDCALQVSPSGYYLDLELSLEEQREMLESFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLNCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIQAVNSVASTTGALPWANLISILEEKNGADAELLVYTV
TLINKTLAALPDQDSFYDMTDALEQQGMEALVQRHLGTPGTDVDLRTQLMLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGYL-VRA-PEPG
-------PTGP------ASS------VGPT------SST---------------------
------------------------------------------------------------
---------GLAPPS----------------------------PVASPTSSASG-LYTSA
NLFP-----TIALAPSIDSPG-ERSVYKLH------------------------------
------------------------------------------------------------
QTAPVWA----------------------------PESPSVPQ-----------------
----------------------------------------SPT-----------------
------------------------------------------------------------
----------------EQAGLE--------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENM
AAAET-----------------------EKQAVLAQGRAETLARAT-SDEAD--GP----
------------------------------------------------------------
---------------------------------------------------PGTRERW--
--SSPEPAS---VPRIPQSTVPRI--L----LR-QQSLDPECKEPLTPPSPKAK------
---PIQEILTPVSRLCIGDLDFSDLGEDEDQDMLNVECVEAEKGIPPPPPLLHLQSGGPP
P-----PPPPLPL-------------------------------PIKGPCPPPPPLAAPP
-PHS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

PLPTKRKTVKL---FWRELKLAGSHTGSG----------SRFGPSPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEKQKIQEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNTTFRCILATLLAV
GNFLNGS------QSRGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRTAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLKV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------TAREVRIMQFCHILREFALEYRTCWERVLQQQKKRATYRERN
KTRGRMITETEKFSGVA-GEVPNNPSVPVAVGSGP--GQGDANNHANMKSLLTSRPEDTT
-HGRRSRGMVQSGSPTVPIA---VGPSTTLPDEPPGSSLPSDTSDEIMDLLVQSVTKNSP
R-ALAVRERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKTP---GLEV------------
---

-------------------VSVVTVRVQYLEDTDPFACANFPEPRRAPACSLDGALPVGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLESFYEEISKGRKPTLILR
TQLSVRVSAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGLVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYAESNAPLFIHAVNSVASSTGALPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLSTAGTDVDLRTQLVLYENALRLED
GDIEEA----TTGGRRERRKPSSEEGKRSRR------------SLEGGGGPAVRA-SEPG
NPERKELGWQAGRC----PS----------------------------------------
-------------------------------------DQPPYSPTGPAPPVSSAS-----
---------CPT------------------DSA------QLTAPTSRPVGPASS-LHASV
SLFP-----SISVAPSADSSC-ERSIYNSYSTLHPALRP-------------YQAPSASS
AQTRAFSLSF---------QTSPNCSCL-----VIS------------------------
--------------------------------------PPLP------PLPGSSSHVPPP
PSSSHCCWEVPSGITAWLCVGASRRTLGWSRYQSHHLFL-SPPSPRAPENPPVPQSPTGQ
ARLDIASPAGVPRAQCSQNRGALRL-----------------------------------
LLFQDYPRTKY-WGRRVTWSLETGRDL-----VRARKAWRSQKKDTESYSLVQNKLSAYQ
ALFWAK--------LPDMLKEGQPGVPNGTAIPFPCPEGC--------------------
--GGDPYQMWRTEQGLALGDR---SWVCLAHELFPGSVCACI----WGQCPGTQQGMCTP
WAEVV----LDTPTDKARFLENVAAAETEKQAALAQGRAETLAGT-MPDEAS--GHSG--
S-----------------------------------------------------------
-------------------------------TMLTAAS-----------FPLDTRELW--
--SSPEPAP---VPRTPQSPAPRV--L----LRAQRSLEPESKEPLAPQSPEPV------
---PIRELPTCAPKLCIGDLDFSDLGEDEDQDMLNVESVEAGKGAS--------------
------------------------------------------------------------
-----VPD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

DPALPTKRKTVKL---FWRELKLAGSPGGSG----------GHFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEDEQQKIEEAQQANPDIPLGP---AENFL
LTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLAENLEQLECRSWAAQESLRGLAKHELAA
ALRARLTHFLAQCARRVA------MLRV-VHRRVCNR--------------------FRA
FLLYLGYTAQ--------GAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GETPSNPAVPVAVGSGP--GRGDADSHASMKSLLTSSPKDAT
-HGRRSRGRIHGP--WRQWA---LGPQWSD-------LLIRSPSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGEEDRGDGEPVSLVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFFEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHTETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLGALPDQDSFYDVTDALEQQGMEALVQRHLSKAGTDVDLRAQLVLYENALRLED
GDLEEAV---TGGRRTTRRKPSSEDGKRSRR------------SLE------VRS-PEPG
-------STGP------ASP------VVST------STT---------------------
------------------------------------------------------------
---------SPVLPAS-----------------------------SPLG-PASG-LHSTL
SLFP-----TISVAPSSDSSC-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGA-MPDDMD--GR----
------------------------------------------------------------
---------------------------------------------------PDTRESR--
--HSQEPTP---APRTPQSAAPRI--L----LRAQQSLEPEPREPLAPPSPKAE------
---PVWELPARVPRLCIGDLDFSDLGEDEDQDMLNVEPVEAEKGIPPPPPPPPLLSGSLS
P-----PPPPPPPPLKSP-FP-----------------------------PAPPPPPAAP
LPHS-APDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

ALPTKRKTVKL---FWRELKLAGVRGGSG----------SHFGPSPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQP---------LLHHL
CALVLQ---ARPDSS---------------------------------------------
------------DLYSEIPALARCAKVDFEQLTENLGQLERRSRAAEDSLRSLAKHELAP
ALRARLTHFLAHCTRRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTAE--------AAREVRIMQFCHTLREFALEYRTCRDRVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GETPSKPSVPVAVSSGL--GEGDADSHATMKSLLASKPEDAT
-HGRRSRGMGQSSSPVMPTA---VGPSTVPLEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------MAGEEDRGDGDPVSVVTVRVQYLEDTDPFSCANFPEPRRAPTCSLDGALPLGA
QIPALHRLLAAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTIILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASMSRLV
VKTALKLLLVFVEYSENNAPLLS-SCHSVASSTGSLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTSGTDFDLRTQLVLYESALRLED
GDIEEA----AVGGRRERRKPSSEEGKRSRR------------SLEGGGGP-VRS-QEPG
-------PAGP------ASP------TGLT------------------------------
-----------------------------------SSPTDP------VSTVI------ST
YST------GPALSSG------------------------QAPS---PLDPASG-LRTSV
NLFP-----AISVGPPADSTS-ERSIYKLH------------------------------
------------------------------------------------------------
QTAPVWA----------------------------PESPPVPQ-----------------
----------------------------------------SPT-----------------
------------------------------------------------------------
----------------EQARLQ--------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------VDTRELW--
--SSPEPGP---APRTPESPAPRG--L----LRTQRSLEPEPKMPLAPPSPKAE------
---PIREF--RVPKLCIGDLDFSDLGEDEDEDILNVEAVEAVKGVPPPPPPLPALSGGAP
P-----PPPPPPPPIKGS-LP-----------------------------PPPPP--AAP
LSPS-APDGLPL

PF02181 // ENSGT00870000136417_3_Domain_0 (1453, 1959)

PTKRKTVKL---FWRELKLAGGHGGSG----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLIQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRGAEESLRSLAKHELAP
ALRARLTHFLAHCGRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAP--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVGSGP--GRGDADSHASMKSLLTSKPEDAT
-HSRRSRGMVQSSSPVMPTA---VGPSTAPPEEPPGSGLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDEEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
AQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLLLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLESGGCP-ARA-LEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SSN------SPTPLTG------------------------PTS---SPVGPPSG-LRASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------A----------------------------PESPPVPQ-----------------
----------------------------------------SPP-----------------
------------------------------------------------------------
----------------GQASLE--------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAEA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPCV--L----LRAQRSLEPEPKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEEEDQDMLNVESVEAGKEVPAPAPPLPLLSGVPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAL
ALRARLTHFLAQRARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDEEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SFT------SPAPLTG------------------------PTS---SPVGPPSG-LRASV
NLFP-----TISVAPSADTSS-ERSIYKLH------------------------------
------------------------------------------------------------
QTAPAWA----------------------------PESPPVPQ-----------------
----------------------------------------SPP-----------------
------------------------------------------------------------
----------------GQASLE--------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAEA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPCV--L----LRAQRSLEPEPKEPLIPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEEEDQDMLNVESVEAGKEVPAPAPPLPLLSGVPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLGGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
ITLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAP
ALRARLTHFLAQRARRVA------LLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGDNRGDGEQVSVVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDQDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASATGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLAVLPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDMEEAP---GMGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------------S------------------------HTS---SPVGPPSS-LQASV
NLFP-----TISLAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGWAETLAGA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------SDARELW--
--DSPETAP---VPRTPHSPAPRV--L----LRTQRSLEPEPKAPLMPSSPKAE------
---PTWELPTHAPKLCIGDLDFSDLGEDEDQDMLNIESVEVGKGVPPPPPPLPLFSGVPP
P-----PPPLPPPPIKG-PFP-----------------------------PPPPL--AAT
LPPS-VPDSAA

PF02181 // ENSGT00870000136417_3_Domain_0 (1452, 1959)

LPTKRKTVKL---FWRELKLAEGHGVSA----------SRFGPYATLWA
SLEPVSV-DTARLEHLFESRAKDMLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-ISGLAGRLQLWAFKLDYDSMEREIAEPLFDLKLGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TQPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLKI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTMREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPIMPT----VGPSTAPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGS---GLEV------------
---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------LGQLMLFVDGMLGVVAHGETVQWLYTLCASLSRLV
VKTALKLLLVFVEYAESNAPLLIRAVTSVASTTGTLPWANLVSILEEKTGTDAELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEAVVQRLLSTAGTDVDLRTQLLLYESALRLED
GDLEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PELG
-------STGP------ASP------RGSS------SST---------------------
------------------------------------------------------------
---------GHFSPTG------------------------PA---SSPVSPTSG-FRTSV
NLFP-----TISVAPSADSCG-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAEALAGA-VPDESD--GH----
------------------------------------------------------------
---------------------------------------------------PGPRERR--
--DSREVAP---PPRTPQSPSPRA--L----LRVQRSLEPEPKEPLTLPSPKDE------
---PFQAFPARVPKLCIGDLDFSDLGEDEDQDILNVESVDAGKGLPPPPPPPPPLSGGPP
P-----PPPPP--PLKG-SFP-----------------------------PPP--PLTAP
PPPS-VPD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GLALPTKRKTVKL---FWRELKLAGGCRGSG----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAEDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVHNATFHCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---SRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEENLRGLAKHELAP
ALRARLTHFLAQCGRRVA------MLQV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSSVA-GDIPSHPSVPVAVGSGP--GPDDADNHASMKSLLVSRPEDTT
-HNRRSRGMVQSSSPVAPTV---VGSPTAPPEEPPGS---SDPSDEIMDRLVQSVTRSSP
R-VVAAKERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

------------------------------------------------------------
--------LGRA-GRQRCLIAL------------------TLGAGLLDSSKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLNCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIQAVNSVASTTGALPWANLISILEEKNGADAELLVYTV
TLINKTLAALPDQDSFYDMTDALEQQGMEALVQRHLGTPGTDVDLRTQLMLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGYL-VRA-PEPG
-------PTGP------APS------VGPT------SSA---------------------
------------------------------------------------------------
---------GLAPPS----------------------------PVASPTSSASG-LYTSA
NLFP-----TIALAPSIDSPG-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENM
AAAET-----------------------EKQAVLAQGRAETLARAT-SDEAD--GP----
------------------------------------------------------------
---------------------------------------------------PGTRERW--
--SSPEPAS---VPRIPQSTVPRI--L----LR-QQSLDPECKEPLTPPSPKAK------
---PIQEILTPVSRLCIGDLDFSDLGEDEDQDMLNVESVEAEKGIPPPPPLLHLQSGGPP
P-----PPPPLPL-------------------------------PITGPCPPPPPLAAPP
-PHS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

PLPTKRKTVKL---FWRELKLAGSHTGSG----------SRFGPSPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEKQKIQEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNTTFRCILATLLAV
GNFLNGS------QSRGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRTAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLKV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------TAREVRIMQFCHILREFALEYRTCWERVLQQQKKRATYRERN
KTRGRMITETEKFSGVA-GEVPNNPSVPVAVGSGP--GQGDANNHANMKSLLTSRPEDTT
-HGRRSRGMVQSGSPTVPIA---VGPSTTLPDEPPGSSLPSDTSDEIMDLLVQSVTKNSP
R-ALAVRERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKTP---GLEV------------
---

--------MGQEEAEEEAALAAVWIRLQFLEDGEPFAGAPFPEPRRPPALALDPARTLAA
QLPLLHRHLQAPLPLEDCALQVLPSGHYLDLEQSLLEQKDELEGFFEDVSKGRRPILLLR
TQLSVRVQAIL--------DKL----YTAKGPELRRSL-FS--LKQLFQEDKDLVPEFVS
LGGLTCLIAVGAEADQNYQNYILRALSQIMLFVDGMMGVIGHNATVQWLYTLCGSLYRLV
VKTALKLLLVFVEYTESNAQLLIQAIAAAEQAKGGLPWSPLVAILEPDSGSDSELQVFAM
TLINKTLAALPDQDSFYDVTDCLEQQGMERIITQHMAGKGTDPGLRHQLTIYESSLRYED
GLEETPEG---P-PGKERRK--GEDGRRGPR-RSLGY-----VSVL-----AASA-VESG
SSQHPP--------------------VAAK------------------------------
------VEKE--------------------------------------------------
----------------------------------------ELQTTHSSVSSVSGLQLSSL
LVGPVEGGGGCSGGETPTSLG-ERSVFKARFLENLAASQ-KE------------------
-------------------------------KLIAISQGRA-------------------
---EV-----------------------------LAEATPSP------------------
-----------EQLGPDVEVGTSDLHDKQRVGR---------------------------
-------P--VT-----ATTKFHNTDLK--------------------------------
-----FARNSS---------------------------------HVTR-----MKVT--P
FSFGVTPSAAKNSVTVLCLSCIDRPSAQ---------------------GSILCALTTQP
FNAKASLSAWFHTSYF-----------------------------------------NNT
T-VQCQ---MELTVEESQLNKPV--PATEQDCHLLRSYPELLAI----TPAS--LSSG--
KWSEGAAQ----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------GANEEEPRTPSLAGSCD
DTEV-----EEPPPAARCPPPLRTPTPPEKKGP--------QCQ----HQQHSPPWTQTP
LLHAEESRGRLLEEEKEDS------------RSGRRPVAGRPGNLDA-----------ES
SLQSLERDTAGPL

PF02181 // ENSGT00870000136417_3_Domain_1 (1514, 1589)

RHLFMERKSRVATPKKAADGKK-LLVVLDPKRSNAINIGLTVLPPIH
IIKQAILNF---DEFAINKEGIESLIKMLNRTGPRTEPCGTPL-------VTSFHDEDDA
LVSTLWVRSLSQ------------------------LQIHLTVVLSSPHFTSLFAR-RSW
GTLSKALLKSRYATSTAFPVST----------QLVTLSKKEVLKPRGYSVPYNLQIKHHS
LSIHLSNH-------------TY-------------------IYLAGVTLKNVPV-----
------------PMYIQIQLKNRTYLILFSRISNAVLTTQCFAI---------SEEDMRL
RLYEKYDHTIKKCKYANINTELNNRIKI-LQSKSIKI--------------YSKQLYIHT
IYYFIS------IAQY--YYTIMVLYTICNIISNVTSQYKYSRVLLIQH--KRAG-RTLD
KRICRIMRQMERFSTGQ---KVEDDPPPAVLSTRL--QQKDEAGHQSMASILIAPSEPSG
RRSRGSRGFSKQSPPSVVPAQPQEGEGEEEPPRVAPTSGPSEEEEEIMDRLVKSVTQSSP
ARPGAGKERKRSRLNRKSLRRTLKNGLSDELVQALGLAKAA---GVTV------------
---

------------MAVVEAAEATVPCRVQYLEDADPFAFGSFPEPRRAPVYAVEEALALGA
QLPALHRLVGCPLPLEDCTLQISPSGHYLDLDLSLLEQKDDLEGFYEEVRKGRRPTLILR
TQLSVRVHAII--------EKL----YNSQGPELRRSL-FS--LKQLFQEDKDLVPEFVN
LEGLTCLIKVGAEADQNYQNYILRALSQIMLFMDGMQGVINHNETVQWLYTLSGSPFRLV
VKTALKLLLVFVEYTEPNALLLIRAVNAVDQAKGACPWSNLMAILEQRNGADTELLVFTM
TLINKTLAALPDQDTFYDVTDCLEQQGMEQVVQQYLGSKGTDLDLKQQFTLYESALKLED
DVEEPP-----IGGRKERRR--TDEGRRGWR------------SQS--GCQDPSADA---
---QPL----LG------SPDTPKEPPAED------------------------------
-----------------------ALPIPALNSPG-STWIHCWCQGGEQSC-G--------
--------NCSQSLSLLPDPVPPAST--TARPVCGWPWPPPRPRRSSPRAQESA-ASTSK
ELGGVGC---MEVPQSSRMGSQEHEVCPSQGT--QTFPGGNQSGRALELEGCMRGQQASK
GPARGSKASFG---------HAQLCSSS--SSFSSLPTLALFS-AH---SFCLSFCRL-H
QTAPVWKGLARAPREPRVH-----------------------------------------
----------------------GARVPWWRAARM-----------------REPQGAAS-
--------------------SMH---------------------------------F---
--------------------------------LGLVPSWRCPGSS---------------
---------------------------------------------HTGHEEQECALKSLP
WCPPGFCSFWMRVAGSEEVESLVSLMQCGQCWGF---LCCGTGCAVWHGVVCRLSLLSPS
---LRFSQPTFTPSYRARFLENLAAAQKEKISSMAKGRLDVLSDTTLEHP------TA-L
AWERDHGTSDSGMEPSSIR---------------------------------SRLAR-SD
ITDSCSTISSDTKFMLDMLFAKGSSESGRE-MFHETPL----SPRSQGEAEMDT-----K
GSSSPEQESARPCGRAPDGPVASAHAK---LVRAMSSIDDETHTQKLENTR--MMPIKKD
TELTWERLEAIPLQLKIKDLDFTDLGEEEDFDILD--TGPVTNGSLLPPGI-EAMSAGTF
------LAPPPPPALPGCPSPPPP---PPALPGCPPPPPPPP---AVPSCPPP-----PG
LPGPSTTDG

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

PSQAKKKRTVKL---FWKELKQLDD--TLG---------PGRFG-QGTLWA
SLQNVEV-NAAKLEHLFESRSKEAPTSKKAIDGKK-VLVVLDPKRSNAINIGLTVLPPIH
IIKTAVLNF---DEFAVSKEGIEKILTMVPTEEEKQKIQEAQLANPDVPLGS---AEQFL
LSLSS-ISDLTARLQLWAFKLDYESLEQEIAEPLFDLKLGMEQLARNHTFKCILATLLAM
GNFLNGS------QSRGFELGYLEK--VSEV-------KDTVHRQS---------LLYHL
CQMVVE---KFPETT---------------------------------------------
------------DLYSEIASITRSAKVDFEELANSLVQLERRCRTSWHHLKVIAKHETKP
VLKTKLTEFLKDSTQRII------VLKV-VHRRVLNR--------------------FHS
FLLYLGYPAS--------AARDVKVTSICKLLREFALEYRTCRERVLQQHKKRAAHRERS
KTRGRLITETEKFSGIAE-----AVLPPAVVSSSP--KEQMEAGHESMKIVLTSPTDVPA
RRSRASQGTGHGTPTQS------------SPAQEDVPSSPDDASDDIMDQLVKSVTLNAN
PRPCPNKERRRSRVNRKSLRRTLKSGLSDDLVQALGLGRAP---GMEV------------
---

-------MAGGEDRGDGEPESVVTVRVQYLEDTDPFSCANLPEPRRAPTCCLDAALPLGA
QIPTLHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGALPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTAGTDVDLRAQLVLYESALRLED
GDIEEAA----PGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------PTSP------ASP------LAP-------------------------------
----------------------------------------------------------TS
SST------GPAPPTG------------------------PTS---SPVGPASG-LRTSV
SLFP-----TISVAPSSDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGA-MPDEVD--RH----
------------------------------------------------------------
---------------------------------------------------PDTRKLW--
--DSPEPAP---APRTPQSPTPRV--L----LRAQQSLEPEPEETLASPSPKVE------
---PIREFPIRIPKLCIGDLDFSDLGEDEDQDMLNTESVEAGKGVLPPPPPVPLLSGGPP
P-----PPPPPPLLIKS-PFP-----------------------------PPPPL--AAP
PPPS-VPDGLAL

PF02181 // ENSGT00870000136417_3_Domain_0 (1453, 1959)

PTKRKTVKL---FWRELKLAGGHGGSQ----------SHFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKEGIEKLLTMMPTDEERQKIEEAHLANPDIPLGP---AENFL
MILAS-IGALAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLRV-VHRRVCNR--------------------FRA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVGSGP--GRGDADSHASMKILLTSKPEDTT
-HGRRSRGMVQNSSPVVPTA---VGPSTVPPEESPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGS---DLEV------------
---

-------MAGEEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTSGALPWANLVSILEEKNGADPELLVYAV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEETA---AMGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRT-LEPG
-------PTGP------TSS----------------------------------------
------------------------------------------------------------
--T------GPALLTG------------------------PTS---SPVCSPSG-LSTSV
NLFP-----TISVASSADNSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAEA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDIREMW--
--DSPETAP---APRIPQSPVPRV--L----LRAQRSLEPEPKEPLTPLSPKAE------
---PIREIPSRVPRLCIGDLDFSDLGEDEDQDVLNMESVEAVEGVPPPPHTLPLLSGGPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPL--AAP
LPPS-ATDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

ALPTKRKTVKL---FWRELKLAGGCGGSG----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TQPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRGLAKHELAP
ALRARLTHFLAQCARRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSIPVAVGSGP--GRGDADSHASMKSLLTSKPEDTT
-HSRRSRGMAQSSSPVMPTA---VGPSTASSEEPQGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDREDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------SPAPLTG------------------------PTS---SPVGPPSG-LRASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAGA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPCV--L----LRAQRSLEPEPKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEDEDQDMLNVESVEAGKEVPAPAPPLPLLSGVPH
P-----P--PPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTGEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAP
ALRARLTHFLAQRARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCVSLSRLV
VKTALKLLLVFVEYSENNAPLFIQAVNSVASTTGTLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTAGTDVDLRTQLMLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------STGP------ASP------VGST------SIA---------------------
------------------------------------------------------------
---------GPTLP-------------------------------TSPTGPATGL-HTSV
NLFP-----TISVGPPVDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGAT-VDDTD--GSL---
------------------------------------------------------------
--------------------------------------------------SSGARELW--
--DSPEPAS---APRTPQSPVSRI--L----LRTQRSLEPEPKEPMSPPSPKAE------
---PIQELPTRVPKLCIGDLDFSDLGEDEDQDTLNAASAESEKPFPLLPQPPSSFSGGPP
P-----PPPPPPPILGSCPP----------------PPPPPP-PPILGSCPPP-PPLAAP
FPHS-VLDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

SLPTKRKTVKL---FWRELKLAGSPGYSR----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLNMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDGMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---SRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSRAAEDSLRSLAKHELAP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLKEFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNLSVPVAVGSGP--GRGDADSHASMKTLLTSRPEDTT
-HSRRSRGMVQSSSPVTNTA---VGTSTASPEETSGSSLPSDPSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

------------------------------------------------------------
--------------IEDCALQVSPSGYYLDPELSLEEQREMLEGFFEEISKGRKPTLILR
TQLSLRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIHVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGALPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRAQLMLYESTLRLED
GDMEEAV---TGGRRITRRKPSSEEGR-IRR------------SLE------VRS-PEPG
-------PVGP------APP------TGPA------------------------------
------------------------------------------------------------
---------------------------------------------SSAVGPVSG-LHTTL
SLFP-----TISVTPSPNSSC-ERSIYX--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------XX---X-------------------------------XXXX
XXAET-----------------------EKQAALAQGQAETLAGA-MHDDID--GH----
------------------------------------------------------------
---------------------------------------------------PDTQELR--
--GSPEPAP---APGTPQSAAPQI--L----LRTRHSLEPEPKEPLAPPSPKAE------
---PIREIPTSVPSLCIGDLDFSDLGEDEDQDVLNTESVEAGKGVPPPPPP---LPGGPP
P-----PPPPPPPPIKSS-FP--------------------------------PPPPAAA
LPPS-APD

PF02181 // ENSGT00870000136417_3_Domain_0 (1449, 1960)

GLALPTKRKTVKL---FWRELKLAGVHGGSG----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTVTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IRGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMQQLVQNATFHCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALIRCAKVDFEQLTENLGQLERRSRAAEESLRSLSKHELAP
ALRARLTHFLAHCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAE--------TAREARVMQFCHTLREFALEYRTCRDRVLQQQQKRATYRERN
KTRGRMITETEKFSGVAAGETPSNPSIPVAVSS-S--GEGDADSHASMKSLLASKPEDTT
-HGRRSRGMVQSSSPVMPTA---VGPCTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ASAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDEEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGHYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------S----------------------------------------------------
------------------------------------------------------------
-----------APLTG------------------------PTS---SPVGPPSG-LRASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAEA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPCV--L----LRAQRSLEPEPKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEEEDQDMLNVESVEAGKEVPAPAPPLPLLSGVPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPSLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAP
ALRARLTHFLAQRARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDCGDGVPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLCA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGALPWANLVSILEEKNGSDPELLVYAV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRAQLVLYESALRLED
GDIEEAA---VTGGRRERRKPSSEEGKRSRR------------SLEGGGCP-TRA-PEPR
-------TIAG------VDQ------P------------------------------G--
----LARLKH------PA-----------------SSPAGP------APPIG------PT
S--------CPPGPTR------------------------TTGASSSPMGAASG-LLASV
SLFP-----SISVAPSADSAS-ERSIYKSPLSNCPRF----C---A--------LLCAPP
Q--------------------------------------RPQPLLPKRMLSLFLSR--LH
QTAPICLSPPLL-TS-----------------SC---------------------HA-SL
IPLLFLLWLGRNPL----------------------------------------------
-----RSLPSPV-WHCFPQRGFHVPDEATVGGLSGPSSPRLMPPPLSKTRDGDVDSRMGP
ILPCSQPRNRAGRGSRVRCGRGVGEQPGLRERQGQPAGAREETPHHFHW-------F---
---HIKPYSG----HKKLPDMLKKEQPAGTAIPFPCPKGPCLELGQCMSTAA-----W-L
WVGSDSPLTWSGPGP---------------------------------------------
--------------------------------------AQ--------------------
------------------------------RMNC--------------------------
-------------------------------------S-----------L----------
-----------CVCVCLHSPVPQV--L----FWAQKSLEPELKEPLAPPSPKAE------
---SIQELPTRAPKLCIGDLDFSDLREDEDQDMLNMESLEAGKGVPPP---LPLISGDSP
P-----PPPPPPPPIKGVPLPPPPPP-----------------LFSGGPPPPPLPPPAGP
LPGS-VPDGLAL

PF02181 // ENSGT00870000136417_3_Domain_0 (1453, 1959)

PTKRKTVKL---FWRELKLAGGHGSSG----------GHFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKGGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLSF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
LTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKMGMEQLVQNATFHCILATLLAV
GNFLNGS------QSRGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TQPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLAENLGQLERRSRATEESLRGLAKHELTP
ALRARLTHFLAHCARRVA------MLKV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPVIPVAVGSGP--GQGDADSHISMKTLLTSRPEDTT
-HGRRSRGMVQSSSPVMPTV---VGPSTAPSEETLGSSSPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

------------------------------------------------------------
-------------QMEDCALQVSPSGYYLDPDLSLEEQREMLDDFYEEIGKGRKPTLILR
TQLSIRVHAIL--------EKL----YRSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQVMLFVDGMLGVVEHSETVQWLYTLCASVSRLV
VKTSLKLLLVFVEYAETNAQLFIHAVNAVANATGAYPWATFVSILEEKNGADPELLVFTM
TLINKTLAALPDQDSFYDVTDALEQQGMEGIVQKHLGSPGTDADLRAQLVLYESALRLED
GDPEEG----VPSGRKERRKPSSEEGKRSRR------------SLEGTGSGINSP-SRAS
CPTLPH------------SK----SPVE-A------------------------------
---------------------------------------HPWEEE---------------
----------------------------NNRVC------TNQQSYSSPIGPAPC-LSSSV
VSFP-----SPTVSIAHP-----PSLFPLL--PSPSLPS-GRWGSRWV--EVMVVRCLR-
-----TWERF---------KGVSRCVCRRETKLPSRPWGPPCA-----------------
---------------------------------------------------------EQV
GVSTEWGWPRLAQPGP----------------AQDAVLS------ASIPLPHVPQGPSGD
LLQ--G--SPPSRNHCFHSSTSGSSAHSSK---------------AQKHRRGE-------
--------------------------------PSTAPDAQTKGSRANKIKLFQK-----K
KQKWFKPSIK----K-----------------------------------------KNPR
WVQSSCKTV-------SL---------SREVGRIPGLGTVPNRSRDRGASLAPSALRNAG
WKGM----RVRGTNRSSPAEPNIAAAETEKQAALAQGRAEALAEA-KLDEAD--GHPG--
ERSCSGGLGVPLGLPLP----Q-SRD---SRIPLCPLV-----------EGGCSAPRRGA
QLLACR-----------VT------------MVTAFFP-----------IFTDPRELW--
--STPEPTPTPHSPSTPRSPLPRP--L----ILAQRSLESEVLTP------EAK------
---VTSEPPTPQPSLQIGDLDFSDLGEDEDQDLLATESAGAGD-----------------
------------------------------------------------------------
---------------

PF02181 // ENSGT00870000136417_3_Domain_0 (1456, 1959)

RKTVKL---FWRELKLGQGLKGR-----------GRFGPNPTLWA
SLEPVTL-DTAKLEHLFETRAKEVMSNKKAAEGRRTMTTVLDPKRSNAINIGLTALPPVH
VIKAALLGF---DEFAVSKDGIEKLLMMMPTEEEKQKIQEAQLANPGIPLGP---AENFL
LTLAS-IGGLAARLQLWAFKLDYDTMEREIAEPLFDLKQGMEQLAQNPTFRCILATLLAV
GNFLNNT------KSCGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CTLVLQ---SQPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEMLAENLGQLERRSQVAEENLKDLIKHDLTP
ALRTRLTHFLSQCARRIA------MLKV-VHRRVCNR--------------------FRA
FLLYLGYPAE--------VAREIRVMPFCHTLHEFALEYRTCWDRVLQQQRKRATYRERN
KTRGRMITETGKFSSMA-EAASSLETVPVAVISGP--DQGDKDTDTSLSSLPSPEPTPTS
-PGMS-RNT-----PSGAPA----VSPTASPEEAPGSGAPSDVSDEIMDRLVQSVTRCRP
R-ALAAQERKRSRGNRKSLRRTLKGGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASATGALPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAA---AAGGRRERRKPSSEEGKRSRR------------SLEGGGCL-VRT-PELG
-------PTSP------AS-----------------------------------------
-------------------------------------------------LIG------PT
SST------SPAPLTG------------------------LAS---SPVSPPSG-LRAVV
NLFP-----TVTVAPLTDNSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAEALAGA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDA------
-----ETAS---APRTPQSPAPQV--L----LQAQWSLEPE-QEPLAPPSPKAE------
---PICEPRTRVPKLCIGDLDFSDLGEDEDQDMLNIESVGAGKGVPPPPPXXXXXXXXX-
--------XXXXPLAKG-PFP-----------------------------PPPPL--AAP
LPPS-APHGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

ALPTKRKTVKL---FWRELKLGGGHGGTG----------SHFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLASPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TQPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVT------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRIMQFCHTLREFALEYRTCRERVLHQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPAVPVAVSSGP--GQGDADSHASMKTLLTSRPEETT
-HNRRSRGMIQSGSPIMPTA---VGPSTAPTEELPASSLPSDTSDEIMDLLVQSVTKSSP
R-ASAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIQAVNAVASATGTLPWANLVSILEEKNGADAELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRFLGTAGTDVDLRTQLTLYESALRLED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRA-PEPG
-------STGS------ASP------VGST------PST---------------------
------------------------------------------------------------
---------GSAPPTN------------------------P---AFSSTGPASGLLRTSV
NLFP-----TISVGPSVDSSC-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGAT-VDDTD--GS----
------------------------------------------------------------
---------------------------------------------------SGTRELW--
--DSPEPAS---APRTPQSPVSRI--L----LRTQRSLEPEPKKPVSPPSPKAE------
---PIQEPPTCVPKLCIGDLDFSDLGEDEDQDTLNVESVEAGKASPFLSSLSPSLSGGPP
P-----PPPPPPPITGSCPPPPPPPLPPPATGSCPPPPPPPP-PPIIGSCPPP-PPLAAP
FTHS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

RHPTKRKTVKL---FWRELKLTGGPGCSR----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AARDVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNLSVPVAVGSGP--GQGDTDNHASMKSLLTSRPEDAT
-HSRRSRGMVQSSSPVSHTA---VGPSAASPEETAASGLPTDTSDEIMDLLVQSVTKSGP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGGDDRGDGEPASLVTVRVQYLEDTDPFACANFPEPRRAPTCTLDGALPLGA
QIPTLHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQTYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYAENNAPLLIRAVNSVASITGALPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTAGTDVDLRTQLMLYESALRLED
GDLEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCA-VRA-PEPG
-------PTGP------ASP------TGSS------------------------------
-----------------------------------------------------------S
SVT------SPTPLAG------------------------PASSPVSPVSPTSG-LRTSV
NLFP-----TISTAPSADSSF-ERSVYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAEALAGA-VPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDTREPW--
--DSPEAAP---IPRTPQSPTPRV--L----LRVQRSLESEPKEPPTPPSPKDK------
---PIQALPTRVPKLCIGDLDFSDLGEDEDQDMLNVESVDAGKGVPPPPP---LLPGGPP
P-----PPPPPPPPIKG-PFP-----------------------------PPP--PLAAP
FPPS-APDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

ALPTKRKTVKL---FWRELKLAGGHGSPG----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------QSRGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCGRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPPVPVAVGSGP--GQDDANSHASMKSLLTTRPEDTT
-HNRRSRGMVQSSSPATPT----AGPSTAPSEEPPGS---SDTSDEIMDLLVQSVTRSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGEEDRGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLAAPLKLEDCALQVSPSGYYLDPELSLEEQREMLESFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASVSRLV
VKTALKLLLVFVEYSESNAPLLIRAVNSVASSTGSLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGASGTDFDLRTQLVLYENALRLED
GDIEEAT---A-GGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRP-SEPC
-------PAGP------ATG------RTGP------ASP------RT----------G--
----PSSPGD------PA-----------------SSPGDP------SSAVI------ST
YST------GPALSTS------------------------LAP---KPAGPASG-LCTSV
NLFP-----AISLGPSADSSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGA-MADEPD--GH----
------------------------------------------------------------
---------------------------------------------------PDTRELW--
--GSPEPGP---APRTPQSPVPRG--L----LRAQRSVEPEPKVPLAPPSPKAE------
---PFQEFPIRVPKLCIGDLDFSDLGEDEDEDMLNVEAVEAVKGVPPPPPPLPALSGGPP
P-----PPPPPPPPIKG-SLP-----------------------------PPPPP--AAP
LPPS-APDGLAL

PF02181 // ENSGT00870000136417_3_Domain_0 (1453, 1959)

PSKRKTVKL---FWRELKLAGGHGGSG----------SRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQQANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMAQLVQNTTFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHEVSP
ALRARLTHFLAQCGRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAP--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNHPSVPVAVGSGP--GRGDADSHASMKSLLTSKPEDTT
-HGRRSRGTVQSSSPVTPTA---TGPSTAPPEEPPGSNLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGEDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRPPTCSLDGGLPLST
QIPALHRLLGAPLKLEDCALQVSPSGYYVDLELSLEEQREMLESFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLNCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHNETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSESNAPLFIRAVNSVASTTGTLPWANMMSILEEKNGADPELLVYTV
TLINKTLGALPDQDSFYDMTDALEQQGMEALVQRLLGTAGTDVDLRTQLMLYESALRLED
GDMEEATAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGYL-VRA-PEPG
-------PTGP------SST------IGLT------SCT---------------------
------------------------------------------------------------
---------DLAPPS----------------------------AVSSPAGLASG-PYTSV
NLFP-----TISVAPSIDSSG-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LEHM
AAAET-----------------------EKQAALAQGRAETLARAT-PDEAD--GP----
------------------------------------------------------------
---------------------------------------------------PGTQELW--
--GSPEPAP---APRTPQSAAPRI--L----LRAQGSLEPETKEPPAPLSPKDE------
---PIQEIPGRVSKLCIGDLDFSDLGEDEDQDILNVESVEAGKGIPLPPPLLPLQSGGPP
P-----PPPPLPP-------------------------------PIKGPCPPPPPLAAPL
-PPS-ALDGP

PF02181 // ENSGT00870000136417_3_Domain_0 (1451, 1959)

PLPTKRKTVKL---FWRELKLAGCHTGSR----------SHFGPSPTLWA
SLDPVSV-DTARLEHLFESRAKDVLPSKKTGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEKQKIEEAQLANPDVPLGP---AENFL
MTLAS-TGGLASRLQLWAFKLDYE-----IAEPLFDLKVGMGQLVQNTTFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CCLVLQ---TQPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRTAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLEV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------TAREVRIMQFCHILREFALEYRTCRERVLQQQKKRATYRERN
KTRGRMITETEKFSGVA-GEVPNNPSVPVAVGSGP--GRGDADSHASMKSLLTSRPEDTT
-HVRRSRGMVQSSSPIMPTA---VGPSTTLPDEPPGSSLPSDTSDEIMDLLVQSVTKNSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKTP---GLEV------------
---

-------MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPAVHRLLGAPLKLEDCALQVSPSGYYLDTELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YSSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-PEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------GPALLTG------------------------PAS---SPVGPPSG-LQASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAGA-MPNEAG--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---AARTPQSPAPCV--L----LRAQRSLAPEPKEPLIPASPKAE------
---PIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPP
P-----PPLPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-VPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLDPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLDQCARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPIMPT----VGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEERNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------SPAPLTG------------------------PTS---SPVGPPSG-LRASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAGA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPSV--L----LRAQRSLEPEPKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEDEDQDMLNVESVEAGKEVPASAPPLPLLSGVPP
P-----P-----------------------------------------------------
------------------------------------------------------------
----------------------------

PF02181 // ENSGT00870000136417_3_Domain_0 (1529, 1959)

KAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAP
ALRARLTHFLAQRARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSGGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDRGDEEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFICAVNSVASATGAPPWANLVSILEEKNGTDPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GGGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-LEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------LT
SST------SPAPLTG------------------------PTS---SPVGPPSG-LRASV
NLFP-----TISVAPSADTSS-ERSIYKQK------------------------------
------------------------------------------------------------
S---PWS----------------------------PLSHCPSA-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------L-------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAEA-MPSEAD--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---APRTPQSPAPCV--L----LRAQRSLEPEPKEPLMPASPKAE------
---PIWELPTRAPNLSIGDLDFSDLGEEEDQDMLNVESVEAGKEVPAPAPPLPLLSGVPP
P-----PPPPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-LPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEEQQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSWAAEESLRSLAKHELAL
ALRARLTHFLAQRARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPNNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPVMPT----VGPSTVPPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGEEDRGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGGLPLSA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YGSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIQAVNSVASTTGTLPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRLLGTSGTDVDLRTQLMLYESALRFED
GDMEEAAAAAAAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-VRT-PEPG
-------STGP------ASP------VGST------SFP---------------------
------------------------------------------------------------
---------GPTLLTS------------------------P---GISPTGPASGL-RTSV
NLFP-----TISVGPSVDSSC-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQAALAQGRAETLAGAT-VDETD--GSS---
------------------------------------------------------------
--------------------------------------------------PSGTRELW--
--DSPEPAS---APRTPQSPVSRI--L----LRTQQSLEPEPKEPVLPPSPKAE------
---PVHELPTRVPKLCIGDLDFSDLGEDEDQDTLNMASVESEKTFPLLPHPPSSLSGGSP
P-----PPPPPPPILGSCPP----------------PPPPPP-PPILGSCPPP-PPLAAP
FSRS-ALDG

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

PTLPTKRKTVKL---FWRELKLAGGPGFSG----------NRFGPCPTLWA
SLEPVSV-DTARLEHLFESRAKDVLPTKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAV
GNFLNGS------KSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TRPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELAP
ALRARLTHFLAQCTRRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAQ--------AAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNLSVPVAVSSGP--GQGDADSHATMKSLLTSRPEDTV
-HSRRSRGMVQSSSPVTHTA---VGASTVSPEETSASSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAP---GLEV------------
---

-------MAGGEDRGDGEPISVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGA
QIPAVHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILR
TQLSVRVNAIL--------EKL----YSSSGPELRRSL-FS--LKQIFQEDKDLVPEFVH
SEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLED
GDIEEAP---GAGGRRERRKPSSEEGKRSRR------------SLEGGGCP-ARA-PEPG
-------PT---------GP------ASP-------------------------------
--------------------------------------------------VG------PT
SST------GPALLTG------------------------PAS---SPVGPPSS-LQASV
NLFP-----TISVAPSADTSS-ERSIYK--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AR---F-------------------------------LENV
AAAET-----------------------EKQVALAQGRAETLAGA-MPNEAG--GH----
------------------------------------------------------------
---------------------------------------------------PDARQLW--
--DSPETAP---AARTPQSPAPCV--L----LRAQRSLAPEPKEPLIPASPKAE------
---PIWELPTRAPKLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPP
P-----PPLPPPPPIKG-PFP-----------------------------PPPPLPLAAP
LPHS-VPDS

PF02181 // ENSGT00870000136417_3_Domain_0 (1450, 1959)

SALPTKRKTVKL---FWRELKLAGGHGVSA----------SRFGPCATLWA
SLEPVSV-DTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
MTLAS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGS------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLHHL
CSLVLQ---TRPESS---------------------------------------------
------------DLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAP
ALRARLTHFLAQCARRVA------MLRI-VHRRVCNR--------------------FHA
FLLYLGYTPQ--------AAREVRITQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRMITETEKFSGVA-GEAPSNPSVPVAVSSGP--GRGDADSHASMKSLLTSRPEDTT
-HNRRSRGMVQSSSPIMPT----VGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---

-------MAGGEDHGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCCLDGALPVGA
QIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLESFYEEISKGRKPTVILR
TQLSVRVTAIL--------EKL----YGSXXXXXXXXX-XX--XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRLV
VKTALKLLLVFVEYTESNAPLFIRAVNSVASATGALPWANLVSILEEKNGADPELLVYAV
TLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLSTAGTDVDLRTQLVLYESALRLED
GDMEEA----STGGRRERRKPSSEEGKKSRR------------SLEGGGSPAVRA-TEPS
-------PTGP------V------------------------------------------
------------------------------------------------------------
----------------------------------------PPAPASKPAGPATG-LQASV
SLFP-----SISVAHSADSSC-ERSIYKARFL----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ENVAAAETEKQAALAQGRAETLAGA-MPDEAD--GH----
------------------------------------------------------------
---------------------------------------------------ADTRELW--
--SSVEPAP---IPRTPQSPTPRV--L----LRAQQSIEPDPKEPLASPSPKAA------
---PIQEL-THAPKLCIGDLDFSDLGEDEDQDMLNMESVED

PF02181 // ENSGT00870000136417_3_Domain_0 (1362, 1960)

GKGVPPPPPLPFLPLGALP
P-----PPPPLPTLTKGLSPPP---------------------------------PPAAP
LHSV-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X------------XXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVH
VIKAALLNF---DEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGP---AENFL
LTLTS-IGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAV
GNFLNGT------QSSGFELSYLEK--VSEV-------KDTVRRQS---------LLYHL
CSLVLQ---TQPDSS---------------------------------------------
------------DLYSEIPALTRCAKVDE-QLAEN-GQLESRSRAAEESLRGLAKHELAP
ALRARLTHFLAQCARRVA------MLRV-VHRRVCNR--------------------FHA
FLLYLGYTAP--------GAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERN
KTRGRLITETEKFSGVA-GETPSNPAIPVAVASGP--GQGDADSHASMKSLLSSSPKDAT
-VGRRSRGMIQSGSPVIPTP---VGPSTAPPEEPAGPGSPSDTSDEIMDLLVQSVTKSSP
R-ALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGP---GLEV------------
---