Query Results 

MEGTHCSLQLRKPITELCYISFYLPRGEVRGFSYKGTVTLDRSNKAFQNCYQVREGSDVI
SLSLQPDEHPGDIFFKQTPTKDILTELYKLTAERERLLANLLSSDHILGITMGNQEGKLL
ELSVSLAPED--DCFRRAGDLQGEPLVGCLNKRS-----TQRS-KKPRRFG-------GG
RESVEAL----PQKRTRR-KGHGGQE-SAPQMGRDHV---CSSNSLPLSRERPSRELLEE
RGNLIPQRARSSSLQ-RIGSCPLEITRMLDPDPGFGSFGLTSEDAELG--RGGSPPD--C
SSTEPG--------DGG--A---GGLPRAPHRLAHQQ--TGFSGSHKHPEKHP-------
-PTERGRREKCAERTHRKKPVSKVVARVQDLSAQVQRVVQMHPEGEGG--------LAVH
PAAQAEFIPSADLLTLPA-----------AKAGAPGSKRQARSSTGTG----------HG
SRRQPAPRRAVNKVLLKVIESEK--L--V-A-TEGKRLSFPLSR--TAPHT-L-PDTGSK
RRAGLSL-----SGHKTLFLDLPR-------SA----GPDSSQGGGGERPP----PPAPG
MVF----NNSSSQSGTHTRMSPVPSPLSPRLP-----SPPQHHRLLRL---PGEREAALD
DSPGRKSGTFSGSTSADTLEPSSSAKV------------------TETKGASSAFLRADQ
PRLV---PGEPLEKILGPGRIT------------A-QPLHQSPPGISSESFPR-------
DCFNEQSASKDLPIRDGG---AWVLGHRAGPACPFLLLEEREKTN-RSELHLDLHPEHSP
TEQDDRTPGRLQAVWPPPKTKDAEEKVGLKYTEAEYQAAILHLKREHKEEIENLQVQFEL
QAFHIRGEHAVITARLEETIENLKHEIEHRWRGGSEEMRDVCISTNDDCP--PKTYRNVC
IQTDRETFL--KPCEGEGKTTRSNQIIPKKLNISSLSQLSPP----NDNKDILAPLQSVE
CISPSQE-KASPL---------------PPAPPPPAVIPP--PPPLPPGLGPLPP----A
PLP---PPVSAGPPPP--PPP-------------PLPPSTGPPL-------PPPPPPLPS
SPLLPSSGGASS------CSSTP-LVPPPPPGLFFGVGPSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1577)

KPAIEPSCPMKPLY
WTRIQISDKSQSATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLRELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLQMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SIFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEG-------------------------
---NRNCSVMIIAKSFKK------------------------------------------
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-----------------------------------------

MEGTHCTLQLHKPIMELCYISFYLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDI-
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLADLLSSDHILGIAMGNQEGKLP
ELSVSLAPED--DCFQNADNWQGELPVGPLNKRS-----THGN-KKPRRFG-------GR
RESFGAL----PQKRTRR-KGRGGRE-SAPLMGKDQI---CSSNSLPLSRTRPNHWLLEG
RGNLLPNGALESSLQ-RRESCPSDIPKTPDTDLGFGSFETAFKDTGLG--REVLPPD--C
SSTEAG--------EDG--F------RRLPKGLEHQQ--TGLSESHQDPEKHPEA-EKD-
--E----MQKPAKRTCKQKPVSKVVVKVQDLSSQVQRAVKTHSKGKER--------IAIC
PDAQAEFVPKADLLTLPG-----------AEAGARGSRRRGKERQGNGSWKSPATEAASI
SSAPASAEGAVNKVLLKVIESEK--L---DEAPEGKRLGFPFRT--SVPHT-R-PEIRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQLRGDDKKPSPPAPAALG
KLF----NNSSSQASTHKQTLPVPSPLSPRLP-----SPQQHHRILRLPALPGEKEAALN
DSPGRKSRVFPGCVSADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PQLV---PGEPLEKSSGPG--K----------TTA-EPQHQSSPGISSESFPWDGFNE--
-Q-----TLKDLPNRDGG---TWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLRYTEAEYQAAILHLKREHKEEIENLQAQFEL
RTFHIRGEHAVITARLEETIENLKHELEHRWRGGCEERKDACISTDDDCP--PKTYRNVC
IQTDRETFL--KPSEGESKTIRSNQLVPKKLNISSLSQLSPT----NDHKDIHAALQPME
GTESNQQ-MAP----PPPPAPPLPA-----------SIPP--PPPLPPGLGSLSP----A
PPM--PPP-------PPPPPPPPPPLPP--------PSSVGP-P------PPPPPPPLPN
FPAPLNPGGP----PP--APTPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNAAPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYEISKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSIFAEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVNTN-----------------

MEGTHCTLQLHNPITELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDIFFKQTPTKDILTELYKLTAERERLLDSLLRSDHILGISMGNQEGKLQ
ELSVSLAPED--DCFQSAGSWSRELPVNSLIRRS-----TQGN-KKPRRSG-------RR
RESPEEH----RQKKTRR-KGRGRQESSAPQMGKDQV---CSSSSLPPARVRPNLRLLEE
RGNLVPQGTLTSSPRRRRESCPANILRTPDADLGFGSSGRTSEDTDLE---GPLSPN--G
SPTEVG--------DAR--I---GRQFKSPRDWESP----SLSESH---EKHSGAERVG-
-TR----KSKSLERTCRKKPVSKVVAKVQELSAQVQRVVRTHPDDVGK--------VTFC
SEMQTEFIPKADFFILPG-----------AKDETPSSRRLGEEQRGVKSLQPQTTEIASI
PNEPASTAGAVNKVLRKVIDSEK--L---DEATEGKTLGFSLNT--RATHT-F-SQTRSQ
RKAGLPQ-----SDHKFLLLDLPHTV-----------RPDSPQPKCDERKPTPQTPTALG
LVF----NNSSPQSSARKRLSPVLLPLSPMCP-----SPQQHHRILPLPPLPSEGESVFD
ECPSRKNSVSSGSPSAVTLEPSSFEKV------------------TETKGGSPTSLRASH
TWLV---SEEPSEKSLRPE--K----------ITA-PPQHQPPPGITSEGIPCDSFSE--
-Q-----TTKDLLNKDGG---AWVLGYRAGPPCPYLLQEEREKSS-RSELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
KTFHMRGEHALITARLEETIENLKQQLDHRWGGGREEMRDACISTDDDGP--PKAFRNVC
IQTDRETFL--KTCESENKTARSNQIVPKKLNIS-LTQLSPT----KDSKDIHAPLQTVE
GISSSQQ-KIS----PPPPTPSLPPP----------PIPP--PPPLPTGLGPLPP----A
PPM--SP-MSAGPPPPPPPPPPPPP----------LPPSAGPPP------P-PPPPPLPS
ALALPNSGGLP---PPPLPPPPPGLAPPPPPGLSFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQINDKSQDATPTLW-DSLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
SKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSKEEDVKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGVTSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQ------------------------------------EAGTDK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPKEYLQPFKDKLEDFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKTGEKEITPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVATS-----------------

MEGTHCTLRLRKPITELCYISFCLPKGEVRGFSYKGTVILDRSNKGFHNCYQVREESDTI
SLSQQLNELPGDIFFKPTPTKDILTELYKLTAERERLLADLWSSNHILGISMGNQEGKLL
ELSMSLAPED--DCSQGAGDWWEECPVGQLNKRS-----THGN-KKPRRSG-------GR
RESFEV------QKRTRR-KGRGGQE-STPQMGKDQI---SSSNCLPPSGAWLNLRLLEE
RGNLVPNGVLTSSLQ-RREGCPPDIPVTPDADLGFANFQTASEDTGLG--RGLLPLD--S
SATDTV--------EDG-----VQEPPRRPHRPEHQQ--TGLPESQEGAKKHPEAQRGG-
-------LGKLAEQTCRKKPFSKVVAKVRGLFTRVQRVVNVDPEREEK--------IAVN
PEVKAEFVTSVDSLTLPG-----------AEAGAHGSRWQSKKQQGTRSLQLPAREKASV
SSLPASTDRAVNKVLRKVIESEK--L---DEATKGQRLSVPVNT--RATQG-L-PETRSK
RRTGVPR-----RGHKSSFVDLPHTIGPDSL---------TLECRGGERKPSAPVPAAPG
MGF----NNSSSQSSSHQQQPPALLPLYPRHP-----SPHQHHRILQLPPPPSERESALN
DSPSRQSSIFSASLSADTLEPPSSAKV------------------TETKGASPASLGADQ
PQLA---AGEASEKSVGLGDTT------------A-EPQQPSPPGVFSEGFPWDHFSEQ-
-------TAKDLPSRDAG---AWVLDYRAGPPCPFLLHEESN----RSKLYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAAITARLEETIDNLRLELEHRRPGGCVELRDACVST-DDCP--PKAYRNVC
VQTDRETFL--KPCEGDSKTTRSNPIVPKKLNISSLSQLSPS----SDNKDAPTPLRNGE
GTSPSRP-KT--------------------------------------------------
------------------------------------------------------------
--AVPGPGGPPP------APAPLGLAPPPPPALFFGFSSSSSQAPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDS-QNASPTLW-DSLEEPDI---QDTSEFEYLFS-KVTSVQKKKPLSETYAEK
NKVKKIIKLLDGKR-SQAVGILISSLHLEMKDIQQAIFNVDDSVVDLETLEALYENRAQE
DELVKIRKCYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESVTSLQRK
VEVVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQVGNAWCNP--GKDFTF----------------KYFHEAGTEK
SVFPLPEPEDFFLASQVKFEDLIGDLRKLKKQLEA-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFQTTVEYF
GMKPKAGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKVNPTASLKERLRQKETSVATS-----------------

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-----------------EKSFQLPAFFSGLRVLKKGATSEGGETITEIKPKDGDLALLKL
TQPVQKSLAQAGPQTVKAGQKSTDPKAPPTLLEQLSQLLNIDMPKAELKAGDPEQPRGE-
-EMG---HSVAQESQSGPGEAQ----------TQS-GEVKPKSPETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSKSRP-ADGPSDSKSPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QTFHIRGEHAVITARLEETIENLKHEIEHRWRGGCEEMRDVSISTDDDCP--PKTYRNVC
IQTDRETFL--KPCEGEGKTTRSNQIIPKKLNISSLSQLSPP----NDSKDVHVPLLSVE
GISLNQQ-KAS----PPPPAPPLLT----------S-IPP--PPPLPPGLEALPP----A
PPP--PP-VSAGP--PPPPPP-------------PLPPSAGPPP------P-PPPPPLPN
FSALPSSGGPP---PA--PAP-PGLAPPPPPGLFFGSQS-SSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMAMVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKNISKERLKIAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLRKPITEVCYISFYLPRGEVRGFSYKDTVTLDRASKGFHNCYQVREGSDLH
SLSLQPNEHPGDIFFKPTPTKDILTELYKLTAERERLLAGLLSSGHILGITMGNQEGKLP
ELSVSLASED--DCFQSTGDWLGEPSVGCLNKRS-----SHGN-KKARRFG-------GR
RESFEGLSQSSLQKRTKR-KGHGGQE-LAPLRGKDQV---YVSSSLPLSRTRSHLWLLEE
RGNLLLNGELTSSLQ-RKERCTLEVPRTLDADSALGSIKKPSEDAGLG--RGGLPPD--C
SSTEPG--------DDR--A---RELKRTPRRLVHQQ--TGLTESHKEPEKEP-------
-AVERRRRAKAAEWTHRKKPVSRVVARVQDLSTQVQRVVKTHPEGEGK--------IAPG
LAAPAEFTPGVDLLTLPG-----------AEAGSWGARGLDQEQQRDRSW----QP-SAG
ECPPASTEGAVNKVLLKVIESEK--L--DDA-AEGKRLGFPFGT--IGAHT-L-PETRSR
RGAGLGR-----GSRKTSFLDLPH-------GG----V----DPGSDEKRLPPLALAAPG
TVI----NNSAFPPSTRKRMSPVPSPLSPRLP-----SPQQHHRILRLSSPPGEREAALD
DSLSGRSRAFSGSLSADTLEPPSSAKV------------------TETKGASSTSLRVGQ
PRLV---PREPLEKTLGPGRTT------------A-QPQHQSPPGISSEGFAR-------
DGFSEQTTAKDLPSKDGG---AWVLAYRAGPACPFLLHEEREKPN-RNELHLDLHPDHSP
TEQDDRIPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVITARLEETIENLKHEIEHRWQGGCEEMRDVCVSTDDDCP--PKTFRNVC
IQTDRETFL--KPCEGEGKTTRSNQIIPKKLNISSLSQLSPP----NDNKDTCV--PPAE
GSSLNQQ-KAAPSPPPP-----------PPAPPLPAAIPP--PPPL-----PLPP----A
PPP---PPVNTGPPPP--PPP-------------PLPPSAGPPP-------PPPPPPPPP
SIPLPNSGGPPP------APAPPGLAPPPPPGLFFGVGPSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1534)

KPAIEPSCPMKPLY
WTRIQISDKSQNSTPTLW-DSLEEPDI---RDTSEFEYLFS-KDIPQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITALHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLTKDLRKLKRQLEG-------------------------
---NGNCSVFMSIASLKS------------------------------------------
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-----------------------------------------

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----------------------------------XYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAAITARLEETIENLKHEIEHRWQGGCEEMRDVCVSTDDDCP--PKTFRNVC
IQTDRETFL--KPCEGEGKTTRSNQIIPKKLNISSLSQLSPP----NDNKDTCV--PPAE
GSSLNQQ-KTTPSPPPP-----------PPAPPLPAPIPP--PPPLQPGLGPLPP----A
PPP---PPVNTGPPPP--PPP-------------PLPPSAGPPP-------PPPPPPPPP
SLPLPNNGGPPP------APAPPGLAPPPPPGLFFGVGPSSGQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1568)

KPAIEPSCPMKPLY
WTRIQISDKSQNSTPTLW-DSLEEPDI---RDTSEFEYLFS-KDTPQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITALHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLED-------------------------
---SQRQIK---------------------------------------------------
------------------------------------------------------------
-----------------------------------------

MEGTHCTLRLHKPITELCYISFCLPKGEVRGFSYKGTVTLDRSNKGFHSCYQVREGPDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLANLLSSDHILGVTMGSQEGKLR
ELSVSLASED--DCFQNAGDWWGELPVGSLNKRS-----THGN-KKPRRFG-------GR
RESTGAL----PQKKTRR-KGRGVRE-PALQMSKDQI---CSSNSLPLSRTRPNLWLLEE
RGNLLPNGALASSLQ-RRESCPPDISRTPDRDLGFGSHETASEDTRLG--RGVLLPD--C
TSTEAG--------DDG--L---QGP---PSRLRHQQ--TDFPESRQDPEKHPEAERD--
--R----TEKSTERTCKKKHVSEVVAKVQDLSSQVQRVVKTHPKGVEG--------IAIC
PPAQSEFFPKADLFSLPE-----------TEAGACGSRRRGKEQQGDRSLQSLARETASI
SSTLSGTEGAVNKVLLKVIESEK--L---DETTEGKRLGFPLST--RAPHA-L-RETRGK
RKSGPPL-----SSHKSLFLDLPHGV-----------SPGSSQPRGDKKRPSPPAPAALS
MVF----NNSSLQSSTRKRASPVSSPLSPRIP-----SPQQHHRILRLSPLPGEREAAVN
DSPGRKNCVLSGSPSADTLEPPASAKV------------------TETKGASSASLRAGQ
P----------LEKSSRSG--K----------TTA-RPQHQSPPGISSESFSWDGFNE--
-Q-----TPRDLPSRDGG---AWVLGYRAGPACSFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKDEIENLQAQFEL
RTFHIRGEHAVITARLEETIENLKHELEHRWQAGCEERRDVCVSTDDDCP--PKTYRNVC
IQTDRETFL--KPCEGESKTTRSNHTVPKKLTISSLSQLSPP----NDNKDIHTTLQSVE
GMSLNQQ-KAS----SPPPAPPLPA-----------SIPP--PPPLPPGLGPLSS----V
PPV--PP-VSAGPLPPPPPPPPPPP----------LPPSAGPPP------P-PPPPPLPN
SPALPNPGGPP---P---APMPPGLAPPPPPGLFFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPTCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELAKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMMVVCKESPKEYLQPFKDRLEEFFQKAK-KEHKKEESHLENAQKSFDTTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESISKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHKPIAELCYISFYLPKGEVRGFSYKGAVTLDRSKKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED-D-CFQRAGDWQGELPVGPPNKRS-----THGN-KKPRRSG-------GR
RESAGAL----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPNLWVLEE
RGNLLPNGALASSLQ-RRESCPPDIPKTPDTDLSLGSFETAFKDTGLR--REVLPPD--C
SSPEAG--------GDGARR---PPSGLEH-----QQ--AGFSESHQDPEKRPEAE----
----KDEMEKPAKQTCKQIPVSKVVAKVQDLSSQVQRVVKPHSKGKAR--------IAIC
PAAHAEFVPKADLLTLPG-----------AEVGAHGSRRRGKERQGDGSSQSPARETASS
SSASACAQGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHR--SVPHT-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQPRGDKKQPCPPAPAALG
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQLHHRILRLPALPGEREAALN
DSPGRKSRVFS----ADTLEPPTSAKV------------------TETKGASPAFLRAGQ
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSESFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVVTAKLEETIENLKHELEHRWRGGCEERRDVCISTNDDCP--PKTFRNVC
IQTDRQTFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GTASNQQ-KALP----LPTAPPLPA-----------PIPP--PPPLPLGLDSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLP--------LSSSAGPPPPP-------PPPPLPN
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETFEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAR-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHKPITEVCYISFYLPRGEVRGFSYKGTVTLDRSNKGFHNCYQVREGSDVI
GLSLQPNEHPGDIFFKQTPTKDILTELYKLTAERERLLANLLSSDHILGITMGNQEGKLL
ELSVSLAPGD--DCFQSGGDWPGEPPVGCLNKRN-----AHGN-RKPRRFG-------GR
RGGSEVL----PHKRTRR-KGRGGQP-LVLQMGKDQT---GSSKSLPLSRTRPNLWLVEE
KGNLLPSGAFTSSLR-WRESYFPEIPGTLGTSRGFGSFRKASEDPRLG--RGGRPPA--C
SSAEPG--------DDG--A---AVPDRDPHRLEHQE--AGLLESQEDTEKHLKA-GKD-
--R----REKSTGHTCRKKSISKVVAKVQDLSTQVQRVVKMHPEGEES--------IAVC
PAAQVEFVPRADWLTLPG-----------VEGGTHGSRWQGREQQGDRAVQLSALE--RT
PGTPASAEGPVNKVLLKVIDSEK--L---DEAAEGKRLGFPPST--PATHT-L-PEARSN
RKAEPPL-----RGHKTLFLDLPCSR-----------GPDWSQPRGSEQRPSPPALAPLS
MLL----NNSSSQWGTHWRMSPVPSPLSPRLP-----GPQQHHRVPQLPPQPAEWEVAPN
DALGPKSSTFSGSSCADTLEPPFSAKV------------------TETKGTSSPSFRAGQ
PQLV---PGEPLEKSSGPG--K----------TSG-RPQYQSPSGISSEGLSRDCFNEQ-
-T-----ATRDLPSRDGS---AWFLGYRAGPACPFLLHEEREKPN-KSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVVTARLEETIENLKQELEHRRRGGCEEMRDACISTDDDHP--PKTYRNVC
IQTDRETFL--KPCEGEGKTIRNNQIIPKKLNISSLSQLSPP----NDNKDIHVPLQAVE
CISPSQQ-KTS----PPPPAPPLPAV---------IPPPP--PPPLPPGLEPLLP----V
PPA--PP-VSAGPPPPPPLP---------------LPASAGPPL------P-PPPPPLPN
SSTLLNSGGP----PP--APTHPGLAPPPPPGILLGVGP-SSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---QDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESITSLHRK
VEIVTGASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMIIVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKALSKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHAPITELCYISFYLPRGEARGFSYKGTVTLDRSNKGFQNCYQVREGSDIS
SLTQHPNEQIGDIFFKQTPTKDILTELYKLTAEKERLLANLLSSDHILGISSGSQGGKLS
ELPVSLVPED--GCVQSAGDWLGELPASSLSKRS--------------SHG-------RR
RESSEAF----LQKRKRR-KGSGRQK-TALQMGKDQI---CSSNSFPLSPTKPNLRLLKE
RGNLVPNGAFTHALQ-RRESCPADIPRILGADLGSGSFRRASEGSGLG--REVLPAD--S
RPTEAR--------DDC--V---QKQPRSTGELEPQQ--TNLPDGQEEGKKPPEAERYR-
-AGKCKFKSKSVDRTCRRKPVLKVVARIQEPATHGQHVVRTHPEGEGW--------IDIC
PEAQHQFIPQETLLTLPE-----------AEARADGSSWQGQEKQGDRSSQSSVEETASA
SACPASAEGAVNKVLLKVIERDR--L---AETTEGRRLGLASDT--RATHG-F-LDARSQ
RRPGLPQ-----SGLRPLSLDLPHPV-----------GADS--------SPPTAPAAAPG
MGF----NNSSPQSSIHKRLSPVPLPPPPRHP-----RPQLHHRILQLPPLPSERDPAFN
DSPHRKSGVSSGLPSAATLEQASSAKVT-----------------ETGQGAWPASFSVGQ
PGPL---PGGPLEKILELE--K----------TTA-QLEHQPPPGSSTDGFSWDSFNE--
-Q-----TTRDLPNRDGG---DWVLGYRAGPPCPFLLHEEREKPH-RSDLYLDLNPDQSP
TELDDRTPGRLQAVWPPPRTKDTEEKVGLKYTEAEYQAAILHLKREHKEEVENLQVSPPP
LSLS-----------------------------------PLCLCLSLPLSFSPSPSLSVC
LSLPSSPPLSLPPLS---LSLPLSLSLPLCLSVSLFLPLSPL-SLPPLSLSVSVSV-SVS
CLSVSVS-L-S-----LSLSLPLPLC---------LSVSL--FPPLPLSLSPLCL----S
LSL--SLSLSLSVCLPLSP-----------PLCLSLSLSLSPPL------PPLSPPSVSV
SVSLPLSLSLSV--CLSLPLSPLSLSPPP---------DSTELGPRK

PF02181 // ENSGT00870000136417_2_Domain_0 (1188, 1648)

PAVEPGCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPNI---RDTSEFEYLFS-KETTHQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQAVGILISSLHLEMKDIQQAIFTVDESVVDLETLAALYENRAQE
DELVKIRKYYETSTDENLKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESINSLHRK
IEIVTRASEGLLSMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQP----------------------------FPPSLPTEAGTEK
SVFPLPEPQDLLLASQVRFEDLVKDLRKLKRQLEA-------------------------
---CEQQMVVVCKESPKEFLQPFKSRLEEFFQKAK-KEHKAEEAHLEKAQKSFETTVGYF
EMKPKAGEKEITPSYVFTVWYEFCSDFKTIWKRESKNISKERLKMAQASVSKLTAEKKVE
TKKIDPAASLVSCTFQRSLQVPTG-TGCTKKCV--------

MEGTHCTLQLHNPIAELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDIFFKQTPTKNILTELYKLTAEKERLLDSLLRSDNILGVSMGSQEGKLQ
ELSVILATEE--DYFQSAGNWHRELPVSSLIRRS-----TQES-KKPRRSG-------RR
RESPEEL----RQKRTRR-KGRGCQE-SAFQMGKDQL---CSSSSLSP-RARPNLRLLEE
RGNLVPQGTLTS-SLRRRESCPANILRTPDADLAFGNSGRTLEDTDLE---GPLSPD--S
SPTEVG-------------DSDVGGQLKSSHQQEPPQ--PNVSES---HGKHAGAERWGS
GTR----KSKSLERTCSKKPVSKVVARVQEPSAPVKRIVRAHHDGKGR--------VAFC
PETQTEFIPKADFLTLPG-----------GEAETPSSGRLEEEQRGIKSLQSSAPERASI
TKEPASTEAAVNKVLRKVIESEK--L---DEATEGKRLVFSLNA--RATHT-F-PETRSQ
RKAGVPQ-----SGRKFLLLDLPHAV-----------GPDSPQPKCDEKKPTPQASAALG
MVF----NNSSPQSSAHKRLSPVPSPLSPRCP-----SPQQHHRILPLPPLPSEGEAVFN
EYSSRKNSVSSGFPSADILEPSSSTKV------------------TETKGASPTSLRASQ
TWLG---SEEASEKGLGPEKIT------------A-PPQHQLPPGIASEGFPCDNFNEQ-
-------TAKDLPNKDGG---VWVTGYRAGPPCPFLLHEEKEKTS-RGELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPRTKDTEEKVGLKYTEAEYQAAILHLKREHKEELETLQAQFEL
KTFHIRGEHALVTARLEEAIDNLKQQLEKR-RGGCEEMRDVCVSTDDDSS--PKTFRNVC
IQTDRQTFL--KPCDAESKAARSSQIVPKKLTIP-LTQLSPS----KDSKDIHAPLQTRE
GTSSSSQQKISSPTPPTPPPLPLPP----------IP--P--PPPLPPGLGPLPP----A
PPI--IPPVCPGSPL----------PPPPPPPPTLVPPSDGPPPPP------PPPPPLPN
VPALPDSGGPPPPPPPPPPPPPPGLAPPPPPGLSFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQINDKSQDATPTLW-DSLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSEAYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFTVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQ------------------------------------EAGTDK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPREYLQPFKDKLEEFFKKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKTGEKEVTPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------PKTE----QKEDLELAR
AEMG---CSADQEKQSSP-EAQ----------TQG-GEVKPKPPETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSTSRP-ADGPSDPKSPDQSP
TEQDDRTPGRLQAIWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFNIRGEHAVITAKLE-TIDNLKHELEHRWXXXXXXXXXXXXXXXXXXX--XXXXXXXX
XXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXX
XXXXXXX-XXXXX-XXXXXXXXXXXX---------XXXXX--XXXXXXXXXXXXX----X
XXX--XX-XXXXXXXXXXXX---------------XXXXXXXXX------X-----XXXX
XXXXXXXXXX----XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX

PF02181 // ENSGT00870000136417_2_Domain_0 (1205, 1648)

XXXXXXQNAVPTLW-DSLEEPDI---QDTSEFEYLFS-KDSTQQKKKPLSETYEKK
NKVKKIVKLLDGKR-SQIVGILISSLHLEMKDIQQAIYNVDDSVVDLETLAALYENRSQG
EELGKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESITSSHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNKTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMMVVCRESPREYLQPFKDKLEE-FQKAK-MEHKMEESHLENAQKSFETTVGYF
GMKPKPGEKEIAPDYVFMVWYEFCSDFKTIWKRESKNISQERLKMAQESVSRLTSEKKVE
TKKINPAASLKERLRQKEASVSTN-----------------

MEGTHCTLQLHNPIAELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDIFFKQTPTKNILTELYKLTAEKERLLDNLLRSDNILGISMGNQEGKLQ
ELSVSLAPTD--DYFQSAGNWSRELPVSSLIRRS-----SQEN-KKPRRSG-------RR
RESPEEL----GQKRTRR-KGRGCQE-SALQMGKDQV---CSSSSFSP-RARPNLRLLEE
RGNLVPQGTLTSSSLRRRESCPANILRTPDADLGLGNSGKTSEDTELE---GPLSPD--S
SPTEVG-------------DTDVGGQLKSSPKQEPPQ--PNLSEN---HEKLPGAERWGS
GTR----KSKSLERTCSKKPVSKVVAKVKEPSAPVQRIVRAHHDVKGR--------VAFC
PESQTEFIPKADFLTLPG-----------DEAETLSSRTLGEEQQGIKSLRSSATERASI
TKEPASTEGAVNKVLRKVIESEK--L---DEATEGKRLGFSLNT--RAIHA-F-PETRSQ
RKAGLPQ-----SGHKFLLLDLPHTV-----------GPDSPQPKCDEKKPTPQAPTALG
MVF----NNSSPQSSAHKRPSPVPSPLSPRCS-----SPQQHHRILLLPPLPREGEAVFN
DYPSRKNGVSFGLPSADTLEAPSSTKV------------------TETKGASPTSLRASQ
TWLV---SEETSEKSLGSEKIT------------A-PPQHQLPPGVASEGFPCDNFNEQ-
-------TAKDLPNKDGG---TWVLGYRASPPCPFLLHEDKEKTS-RSELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
KTFHIRGEHALVTARLEETIDNLKQQLEKR-RGECEEMRDVCVSTDDDCF--PKAFRNVC
IQTDRETFL--KPCDVESKTTRSSQIVPKKLTIS-LTQLSPS----KDSKDFHAPLQTRE
CIPSSSQQKISPPAPPTPPPPPLPF----------SSLPL--PSPLLPSPPPHPP----S
PPP---PPHPPLPFP----------PPSPPPPPSPLPPHYGTTTPPPTTP----PHPLT-
PPAYPPSSF---HPPPIAPPHLFLLRTPPPPLLKFVCKKSSCQKIRVK

PF02181 // ENSGT00870000136417_2_Domain_0 (1189, 1597)

ALEPLCSMKTMT
WYQIMLSFSSQDATPTLW-DSLEEPHI---MDTSEFEYLFS-KDTTQQKKKPLSEAYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSREEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQYRYHDQEAGWGGKGSFSLHFHIAVHHQRKSGLELKQEAGTDK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEQQMRLVCKESPREYLQPFKDKLEEFFKKAK-KTH---------------------
------------------------------------------------------------
-----------------------------------------

MEGTHCTLQLHKPITELCYISFYLPRGEVRGFSYKGTVTLDRSSKGFHNCYQVREGPDIA
SLSQEPSEHPGDIFFKQTPTKDILTELYKLTTERERLLASLLSSDHILGITMGSHEGKLP
ELSVSLAPED--DCFQSAGDWPGELPVGSLNKRS-----AHRN-KKARRFG-------GR
RENFEVL----LQKKTRR-KGRGGQE-SAPQMGKDQI---CFSNSLPRSRARPNLWLLEE
RGNLLPNGALTSSLQ-RRESCPPDISRTVDADPGFGNFGTASKDDGLG--RGALPTD--R
SSPEAG--------DGG--I---RGPLRRPHGLEHQQ--TGLPGSHRDPEQHPEA-GRE-
--G----TEKSAERTCERKPVSKVVAKVQDLSFQVQRAVKTHPESRER--------TAVC
PAAQAEFIPKADLLTLPG-----------AEAGVRGSRWQGKEQRGHEPLQSSASATASV
STAPASAEGAVNKVLLKVIESEK--L---DEATEGKRLGFSKRA----TQA-L-PETRSK
KRGRLPP-----SGRKSLFPD----G------A----GPGSSPPRGDEKRPSPPAPAAIS
VAL----NNSSPQSSTHKRTSPVSSPLSPRLP-----SPEQHHRILRLPPLPGEREAALH
DSPGRKSSVFSGSPFADTLEPPSSTKV------------------TETKGASPASLRAGQ
PRLA---PGETLEKSVGPE--R----------TTA-QAQHRSPPGISSEGFPWDSFSD--
-H-----TPKDLPNRDGS---TWVLGYRTGPACPFLLHEERGKAN-RSELYLDLHPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAGILHLKREHKEEIENLQAQFEL
QAFHIRGEHAMVTARLEETIENLKHELEHRWRGGCEERRDACISTDDDCP--PKTFRNVC
IQTDRETFL--KPCEGESKTTRSNQIVPKKLNISSLGQLSPP----NDCKDIHTPLQSVE
GMSSNQQ-KTS----PPPPAPPLPS-----------SVPP--PPPLPPGLGPLSP----A
SPM--PP-VSAGPPPPPPPPP--------------LPSSAGPPP------P-PPPPPLPS
SLVPPSPGGP----PP--APAPPGLAPPPPPGLFFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQINDRSQNATPTLW-DSLEEPNI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEV-------------------------
---SEKQMTVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEEGHLENAQKSFETTVEYF
GMKPKSGEKDITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVATN-----------------

MEGTHCTLRLRKPITELCYISFCLPKGEVRGFSYKGTVILDRSNKGFHNCYQVREESDTI
SLSQQLNELPGDIFFKPTPTKDILTELYKLTAERERLLADLWSSNHILGISMGNQEGKLL
ELSMSLAPED--DCSQGAGDWWEECPVGQLNKRS-----THGN-KKPRRSG-------GR
RESFEV------QKRTRR-KGRGGQE-STPQMGKDQI---SSSNCLPPSGAWLNLRLLEE
RGNLVPNGVLTSSLQ-RREGCPPDIPVTPDADLGFANFQTASEDTGLG--RGLLPLD--S
SATDTV--------EDG-----VQEPPGRPHRPEHQQ--TGLPESQEGAKKHPEAQRGG-
-------LGKLAEQTCRKKPFSKVVAKVRGLFTRVQRVVNVDPEREEK--------IAVN
PEVKAEFVTSVDSLTLPG-----------AEAGAHGSRWQSKKQQGTRSLQLPAREKASV
SSLPASTDRAVNKVLRKVIESEK--L---DEATKGQRLSVPVNT--RATQG-L-PETRSK
RRTGVPR-----RGHKSSFVDLPHTIGPDSL---------TLECRGGERKPSAPVPAAPG
MGF----NNSSSQSISPQQQPPALLPLYPRHP-----SPHQHHRILQLPPPPSERESALN
DSPSRQSSIFSASLSADTLEPPSSAKV------------------TETKGASPASLGADQ
PQLA---AGEASEKSVGLGDTT------------A-EPQQPSPPGVFSEGFPWDHFSEQ-
-------TAKDLPSRDAG---AWVLDYRAGPPCPFLLHEESN----RSKLYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAAITARLEETIDNLRLELEHRRPGGCVELRDACVST-DDCP--PKAYRNVC
VQTDRETFL--KPCEGDSKTTRSNPIVPKKLNISSLSQLSPS----SDNKDAPTPLRNGE
GTSPSRP-KTAPPPPXXXXXXXXXXX----------XXXX----XXXXXXXXXXX----X
XXX--XX----------------------------XXXXXXXXXXXX---XPPPPPPLLI
SQAVPGPGGPPP------APAPLGLAPPPPPALFFGFSSSSSQAPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1534)

KPAIEPSCPMKPLY
WTRIQISDS-QNASPTLW-DSLEEPDI---QDTSEFEYLFS-KVTSVQKKKPLSETYAEK
NKVKKIIKLLDGKR-SQAVGILISSLHLEMKDIQQAIFNVDDSVVDLETLEALYENRAQE
DELVKIRKCYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESVTSLQRK
VEVVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQVGNAWCNP--GKDFTF----------------KYFHEAGTEK
SVFPLPEPEDFFLASQVKFEDLIGDLRKLKKQLE--------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

MEGTHCTLQLHKPITELCYISFCLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED--DCFQSAGDWQGELPVGPLNKKS-----THGN-KKPRRSG-------GR
RESFGAL----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPNLWVLEE
KGNLLPNGAPASSLQ-RRESCPPDIPKTPDTDLGFGSFETAFKDTGLG--REVLPPD--C
SSTEAG--------GDGIRR---PPSGL-----EHQP--TGSSESHQDPEKHPEAE----
----KDEMEKPAKRTCKQKPVSKVVAKVQDLSSQVQRVVKTHSKGKET--------IAIR
PAAHAEFVPKADLLTLPG-----------AEAGAHGSRRQGKERQGDGSSQSPAGETASV
SSVSASAEGAVNKVLLKVIESEK--L---DEAPEGIRLGFPVHT--SVPHT-R-PETRNK
RRAGLPL-----GGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPSPPAPAALG
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFSGCVSADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCP--PKTFRNVC
VQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GMASNQQ-KALP----PPPAPPLPA-----------SIPP--PPPLPSGLGSLSP----A
PPM--PP-VSAGPPPPPP----PPPLP--------PPSSAGPPP--------PPPPPLPN
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQSATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLRKPITEVCFISFYLPRGEVRGFSYKGTVTLDRANKGFHNCYQVREGSDVI
SLSLQPNEHPGDIFFKQTPTKDILTELYKLTAERERLLANLLSSDHILGITMGNQEGKLL
ELSVSLAPED--DSFQSVGDWPGEPPVGCLSKRS-----AHGN-RKPRRFG-------GR
RGSFEGL----PQKRTRR-KGHGGRQ-SALQMGKDQI---CSSKSLPLSRTRPNLWLLEE
RGSSLPRVAFTSSPQ-WRQSCPPEISRTLDPSRGFGNFRKAFQDTGLG--RGRLPPD--C
SSTEPG--------DDG--A---GKPERGHLQLPHQQ--TAWSESREDSEKHPEA-KRG-
--Q----KEKSTEHTCRKKPISKVVAKVQDLSTQVQRVVRTGPESEES--------VAVC
PAAQAEFIPRADWLTLPE-----------AESGTPSSRWQGQEQLGDRPWQLSDGECI--
---PASAEGAVNKVLLKVIQSEK--L---DEATEGKRLGFPPST--PGTHT-V-PEARGK
RKAGLPL-----RDHQSSLLDLPHHG-----------GPDWPQPGGHEKKPSPSAPASLS
MLL----NNSSSQSSTHRRMAPVPSPLSPRLP-----GPEQHHGVLQLPPLPGEWDVAPD
DSAGRKSSAFSGSSSADTLEPPSSAKV------------------TETKGAGSTFLRAGQ
PRLV---SGESLEKSLGPG--K----------TAA-RPQYQSPPGISSEGFPRDCVSEQ-
-T-----ATKDLPPKDGG---AWFLGYRAGPACPFLLHEEREKPN-KSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVVTARLEDTIETLKRETEHRWRGGREEMKDACISTGDDCP--PKTYRNVC
IQTDRETFL--KPCEGEGKTIRSNQIIPKKLTISSLSQLSPP----NDNKDAHGPLQSVE
GLSPSQQ-KAS----SPPPATPPPAV---------APPPP--PPPLPPGLGPLSP----V
PPL--PPPVSAGPPPPPPPP---------------LPPSAGPPP------PPPPPPPLPS
SPALPTSGGP----PP--PPTPPGLAPPPPPGLFFGVGPSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESITSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SIFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMIVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKAISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPKSQLKAEDPEPPRR--
-EMG---CGVAKGSQGGPPEAQ----------AQD-DEVKPKPPESALEAFKALFIRPPK
KG-----TTADASELE-----ALKRKMKHEKESLRAVFERSKGRP-TDGPCDCRSLDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKRKHKEEIESLQXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXX
XXXXXXX-XXXXX-XXXXXXXXXXXX---------XXXXX--XXXXXXXXXXXXX----X
XXX--XX-XXXXXXXXXXX----------------XXXXXXXXX------X-----XXXX
XXXXXXXXXX----X---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX

PF02181 // ENSGT00870000136417_2_Domain_0 (1208, 1648)

XXXQNTEPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSESYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLTALYENXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXFLHELAQIPNFAERAQCIIFRSVFSEGMTSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLEDDVVKDYLRYYDQXXXXXXXX--XXXXXXXX------------------------
----------XXXXXXXXXXXXXXXXXXXXXXXXX-------------------------
---SEKQMVVVCKGSPKEYLQPFKDKLEEFFQKAK-NEHKMEVSHLENAQRSFETTVKYF
GRKPKSGEKDITPNYVFMVWYEFCSDFKTIWKRESKNISKERLKTAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLLKPITELCYISFYLPWGEVRGFSYKGTVTLDKSSKGFHTCYQVREGSDII
SLSQQPNEHPGDIFFKQTPTKDILTELYKLTAERERLLANLLSSHHILGITMGNQEGKMS
AVSVSLALED--DYSQGADEWQGEPPGDSVNKKS-----AHRN-RKPQRCG-------GR
KESFEVL----LQKRTRK-KGRGDQE-SALQMGKDEI---SSNQSLPHSQARPHLRLLEE
RGNLPPSGALSTSLQ-RTDSRPPGIPSSLDTDPGVGSFGMASENTRLG--RGVLPPD--S
SSTEAG--------NDG--F---RGPRRRTHRLEQHQ--SGSHENL---EKH--------
-PSERGWREKSAEQTCKKKPVSKVVAKVQDLPTQVKKVVKTHPEGQER--------VAIC
QADPAEFSPKTDLLTVPG-----------AEAGAQHSRWQVKVQQGDRPLSLARAR-TSA
SSVPASAEGAVNKVLLKVIESEK--V--DEA-SEGKRLGFPLST--KTTHV-L-PERRNK
RKTGLPL-----SDHKALFLDLPH-------GA----GPDSSQPSGDGKRLALPELAAVD
VVF----NNSSSQSDSHKRMSPVPFPLSPGLP-----SPPQHHRILRIPPLPGEREAALN
DSPGRTRGAFSGSPSADALEPPSSAEV------------------TETQGASSTSLRADQ
PRLV---PREPFEKSWGSGKTT------------A-WPQHQSPPGISSECFPQ-------
DGYNEQTATKDLPKRDGS---AWALGYRSGPTYPFLLHEEREKPN-RSELSLDLHPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVITARLEETIENLKHELEHRWQGECEEMRDACISTDDDCP--PKTFRNVC
IQTDRETFL--KPCEGESKTARSNQIIPKKLNISSLSQLSPP----NDNKDIHASLQSVE
GISSNQQ-KTSPPLPPPPPPPP-PLPPLSPAPPLPASIPP--PPPLPPGLGPLPP----T
PLT---PPVSAGPPPPPPPPP-------------PLPPSAGPPL-------PPPPPPLPN
SSLLPNSGGPPS------APTPPG--PPPPPGPFFGFGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1533)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---QDTSEFEYLFS-KDSTQQKKKPLSETYEKK
NKIKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLQRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLDILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLE--------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----MEDLG--DALNGRDASEPEQP----EAGLDMAQSILSK-FSMKSLF-------GF
KSKLESV----KPEE---------------------------------------------
------------------------------------------EDAV--------------
--------------LKA--F---QTEARVPPDFEHDG--KAAG-----VEKELEG---R-
-QR----GAEAGIPLAGQVPLDS-----------------------------------VS
VSGDNVVLVRGTLVNTTS-----------DS----DSDDGGQEPEEGSNTNG--------
---P----EPPDFVLSEPFEEPQ------EKTGDGRR-DVAAGE--TG----------TT
SDGDLCG-----EVPQRTALEISHKSEADDGGLQTEHSPG-QRLAGEEGSKVLPVVTDQN
LSVGVTENASSKKEDSGEKSFQLPAFFSGLRVLKKGAPAEGGETITEIKPKDGDLALLKL
TQPVQRSLAQAGPQTVKTGEKTNDPKAPPTLLEQLSQLLNIDVPRAEPKVEDPEQPRGA-
-EMG---CHAPGKSESSPGEAQ----------TQG-GEVKLKPPETALEAFKALFIRPPR
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSRSRP-GDGPSDSKSPDHSP
TEQDDRTPGRLQAVWPPPKTKDAEEKVGLKYTEAGNIQRSQVP--RANLLPQWLSAQFEL
QAFRIRGEHAVITAKLEETIENLKYEIEHRWQGGCEEMRDVCVSTNDDCP--PKTFRNVC
IQTDRETFL--KPCEGEGKTTRSNQIIPKKLNISSLSQLSPP----NDNKDTQVPLQSAE
GMSSSQQ-KAP----PPPPPPPLPI-----------AIPP--PPPLPPGLGPLPP----A
PPP--PP-ANTGPPPPPPPPP-----------------------------------PLRA
--------------TS--CSSTPRTCPPPPPGLFFGVGP-SSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNSTPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEEWKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESISALHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLVKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDRLEEFFQKAK-KEHKMEESHLENAQKSFETTVEYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKSISKERLKMAQESVSKLTAEKKVE
TKKINPTASLKERLRQKEASVSTN-----------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------ILSK-FSMKSFF-------GF
TTKLEST----KPVEEDA-VLKTFRNLGSEPQG----------------------QLENN
-----------------------------------------NK--DL-EAKSQFPPVL--
--------------QNC------KG--NANVEHEPEN--VGCPGKEE-------------
-------------------------------------------DGGFLLWQETHPFSPLS
PSRDDVLLVHGTLVHTTS---------------DSESDGEGLEEKEDKNISNTPSDTF--
----LLCESSANPQETPGESRKKESM---NEMVE-MNLSVEVSS--VTPSE-L-------
------------------VSDL----EQREDGL----GPR-QDHPGEEDSPTISWTIDKS
SFAGNSENMSSKKEASVEKSFQLPTFFSGLRVLKKGTTTEGGETITEIKPKDGDLALLKL
TQPVQKSRAQPGTLSRKSGEKTPDLKATPTLLEQISQLLNIDMPKNEQKGEVCEQFKEKE
V--G---PNTDHESQYKTEEVP----------FQN-EEVKPKPPETALEAFKALFMRPPK
KG-----STADTSELE-----AIKKKMRYEKESLRAVFERSKSRP-GDGSSDSRSADQSP
TEQDDRTPGRLQAVWPPPKTKDEEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RVFHIRGEHAVITARLEETIENLKCELEHRLSGGCEKTRDACISTEDDYP--PKTFRNVY
IQTDRETFL--KPSEDESKTIKSNQIVPKKLNISSLNHISPP----SDNKDIASSLQSLE
NSSSGQQ-KSP------PPAAPMPS-----------MIPP--PPPLPPGLGPPLLSLQ--
--------SSIGPPSLPPPPPPPPP-----PPPPPLPLTTGNPL-------PPPPPPLPV
PSALPCTGLPPPP-----PPGPPGIGPLPPPPPFFGGNTSFSQIPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1533)

KPAIEPSCPMKPLY
WTRIQISGGRKSSIPTGW---LREKKI---IPFTHFQYLCPSLDISQIKRKPLINLYLKK
TRNRKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLEALYENRAQK
DELIKIRKHYETSKEEELKLLDKPEQFLYELAQIPNFAERAQCIIFRSVFSEGITSVHRK
VEIITRASKGLLDMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLIDYVVKYYLRHYDS------------------------------------EAGTEK
STFPLPEPQDFFLAAQVKFEDLIKDLRKLKRQLE--------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

MEGTHCTLQLRKPITELCYISFCLPKGEVRGFSYKGTVILDRSNKGFHNCYQVREGSDTV
SLSQQQNELPGDIFFKQTPTKDILTELYKLSAERERLLANLRSSDHILGISMGNEEGKLL
ELSVRLAPED--SCSHGAGDLWREPSVGPLNKRS-----AHGS-RKPRRLG-------GR
RESFDV------PKRTRR-KGRGGQE-STPQMGKGQI---CSSHCLPPSGVPLNHRLLEE
RGNLAPHGVLTCSLQ-RRESCPTEIPWTPGADLGSANSGMVSEQPALG--RGT--PSAHS
HSTEAG--------GDG--V---PDAPSRPHGLEHPQ--TGLPESQEDAKKHPEAQRA--
--G----LGKLAEQTCRRKPVSRVVAKVQDLSTQVQRVVNMPPEVEEE--------IAAY
QEVKVEFIPKVDLLTLPG-----------TKAEAHSSGPQGKEQQGARPLQPLAGEITSV
SRLPASADGAVNKVLLKVIESEK--L---DEATKGKRLGVPLNT--GATHD-L-PETRSK
RRAGVPQ-----RGHKTLFPDPPCTA-----------DPGSSQCRGDERMQSPPLPAAPG
LGF-----NNSSQQPPHKQLPPAPSPLHPRCP-----SPQQHHRVLLLPPLPGETEAALN
DSPGRQSDIFSEPSFSDTLEPPSSERV------------------TETEGASPASISAGQ
PRLV---PGETLERSLGPG--K----------TPA-QPQQQASPGVSSEGLPWDRFSE--
-Q-----TAKDLPSRDGS---AWVLGYRAGPPCPFLLYEDREKSN-RSKLSLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAAITARLEETIENLKHQLECRWRGGCQELRDACVST-DDCP--PKAYRNVC
IQTDRQSFL--KPCEGESKTARSNHIVPKKLNISSLSQLSPP----NDNKDIHTPLQNGE
GSSPSHP-KTSPP------APPMPPP---------LPIPP--PPPLPSVLGTSVP----P
EPP--TPAVSAAPPPPPPPLPPPP-----LPPPPPLPPSAGPLV------P-PPPPPLPN
SQAVPSSSGTPP------TPASLGPAPPPPPGLFFGLS

PF02181 // ENSGT00870000136417_2_Domain_0 (1179, 1648)

SSSSQAPRKPA-----------
------------------------------------------------------------
-----IIKLLNGKR-SQAVGILISSLHLEMKDIHQAIFNVDDSVVDLETLEALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGVTSLHLK
VEIVTRASKGLLHMKSVKDILAIILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRVF
IF-LNEFLC-----ISHT-------------------------TFGKLLQVQREFAGTEK
SVFPLPEPQDFFLASQVKFEDLTEDLRKLKKQLEA-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFQEAK-KEHKMEESHLENAQKSFQTTVKYF
GMKPKAGEKEVTPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQALVSKLTSEKKVE
TKKINPTASLKERLCQKEASMATN-----------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGAVTLDRSKKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED-D-CFQSAGDWQGELPVGPPNKRS-----THGN-KKPRRSG-------GR
RESAGAV----PQKRTKR-KGRGGRE-SAPLMGKDQV---CSSHSLPLSRTRPNLWVLEE
RGNLLPNGALASSLQ-RRESCPPDIPKTPDTDLSLGSFETAFKDTGLR--REVLPPD--C
SSPEAG--------GDGARR---PPSGLEH-----QQ--AGLSESHQDPEKRPEAE----
----TDEMEKPAKQTCKQIPVSKVVAKVQDLSSQVQRVVKTHSKGKAR--------IAIC
PAAHAEFVPKADLLTLPG-----------AEVEAHGSRRRGKERQGDGSSRSPARETASI
SSASACAQGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHR--SVPHT-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPCPPAPAALS
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFS----ADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVITARLEETIENLKHELEHRWRGGCEERRDVCISTSDDCP--PKTFRNVC
IQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GMASNQQ-KALP----LPTAPPLPT-----------SIPPPPPPPLPLGLGSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLP--------LSSSAGPPPPPP-------PPPLPN
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1535)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETFEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEG-------------------------
---SRNCSVIM-------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----MEEVG--NSLNGSDVS----EPEKSEAGLEMAQSILSK-FSMKSLF-------GF
TNKLESV----KPEEEDA-VLKAFRSLDVDPTSQ--------------------------
-----------------------------QDDPS--------------------------
----KG--------SDE--L---EAEAQVPPDLRNAG--KTE-----SVERESEGSQGK-
--------AEA-------------------------GSSLGGQELLPL--------ATLN
VGRDDVICVRGTLVHTTS-----------DS----DSDDGGQEPEEGSSTNDPKSFSVNL
------SEPSQEPKENPGGSRENAST---G----------------------------EM
DDAELCA-----ENPQRSASEISSKLEPGDDGLQTEHSPSQ-GQAGEEGSQVPPIATGKN
SSADITASVSLKGEVPGEKSFQLPAFFSGLRVLKKGATAEGEETITEIKPKDGDLALLKL
TQPVQKSLVQTGPQTVKSRERASDPKATPTLLEQLSQLLNIDMPKTELKGADPKSHGGG-
-EMG---CSADQESQRDSEDVQ----------TQS-GEVKPKPPETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSKSKP-ADSSSDSKSPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVITARLEETIENLKHELEHRWRGGGEEMRDVCISTDDGCP--PKAYRNVC
VQTDRETFL--KPCEGESKTTRSNQIVPKKLNISSLSQLSPP----NDNKDIHVPLPTGE
GISSNQQ-KISPPPPPPPP-PPLPP-----------TIPP--PPPLPPGLGSLPP----A
PPP--PP-VTAGPPPPPPPPPPPPP----------LPPSAGPPL------P-PPPPPLPN
SPALPSSGGPP---P---APTPPGLVPPPPPGLFFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRGQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIVTRASKGLLHMKSVKDILGLILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKAGEKEITPGYVFMVWYEFCSDFKAIWKWESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGAVTLDRSKKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED-D-CFQSAGDWQGELPVGPPNKRS-----THGN-KKPRRSG-------GR
RESAGAL----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPNLWVLEE
RGNLLPNGALASSLQ-RRESCPPDIPKTPDTDLSLGSFETAFKDTGLG--REVLPPD--C
SSPEAG--------GDGARR---PPSGLEH-----QQ--AGLSESHQDPEKRPEAE----
----KDEMEKPAKQTCKQIPVSKVVAKVQDLSSQVQRVVKAHSKGKAR--------IAIC
PAAHAEFVPKADLLTLPG-----------AEVGAHGSRRRGKERQGDGSSQSPARETASS
SSASACAQGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHR--SVPHA-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPCPPAPAALG
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----GPQQHHRILRLPALPGEREAALN
DSPGRNSRVFS----ADTLEPPSSTKV------------------TETKGASPAFLRAGQ
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHADHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVVTARLEETIENLKHELEHRWRGGCEERRDVCISTNDDCP--PKTFRNVC
IQTDRQTFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GTASNQQ-KALP----LPTAPPLPA-----------PIPP--PPPLPLGLDSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLP--------LSSSAGPPPPPP---P---------
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETFEKK
SKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAR-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
-----MEEVG--NSLYSNNV----SEPEKVEAGLEMAQSILSK-FSMKSLC-------GF
TSKLESV----NPEEKDA-VLKAFR-----SLQ-----------------VSPT------
----------------------PEL-----EDPSYS--------S---------------
---------------DK--Q---QAEPWGPPDFKDNG--EM-AK----VEIESEGSQ---
--G----KA---------------------------ESGTSGPEMCPL--------ATLN
VGSDDVIWVRGTLVHTTS-----------DS----DSDDGDQVAEEGSSTNGLKFPVA--
----LSSEPPQEPKERPGDSRENIAP---EEM-E----GTELCA--KDLQK-VPPETSSQ
LELEDG-----------------------DRGLAA-EPSRSQGQAGEEESQVPPAARRQN
LSVDVTENISSKREVPGEKSFQLPAFFSGLRVLKKGMVAEGGETITEIKPKDGDLALLKL
TQPVQKSLLQAGPQSVRSEERTTDPKATPTLLEQLTQLFNIDMPKTELKAADPELPREE-
-EMG---YSANQEGQNGSGDAQ----------IQS-GQVKSKPPETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSKSRP-ADSPSDSKSPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVITAKLEETIENLKYQLEHRWGGGCEEMRDACISTDDNYP--PKTYRNVC
IQTDRETFL--KPCEGESKTTRSNQIVPKKLNISSLSQLSPS----KDNKDIHATLHTGE
NMSSSQQ-KTSP--PPP---PPLPPL---------PPIPP--PPPLPPGLGLLPP----A
PPL--PP-VSAGPPPPPPPPPPPPP----------LPLSSGPPP------P-PPPPPLPN
TPPLPNSGGVP---P---APVPLGLVPPPPPGLSFGLSCPSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPTCPMKPLY
WTRIQISDKSQNATPTLW-ESLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELIKIRKYYETSKEEELRLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESITSLHRK
VEIVTRASKGLLHTKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEQQMKVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQNSFETTVGYF
GMKPKTGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
--------ME--DGAGSPNGSDGPTPEHSTEDGIEITQSILSK-FSMKSFF-------GF
TTKLEST----KPA-----EEDAVLK-AFRNLGP-----------------EPLLQLESN
NK----------DQE-TKAQFPPALLNCKDNTIGESA-------PE--------------
------------------------------------K--EGCPEKEQD------------
-----------GGFLLSEEPH-------------------------PS--------SPLS
SSRDDDILVHGTLVRTTS---------------DSESEGEGLEEKEGKNIGS------TI
PHSSVSSGPSVDPKEIPGETRRNETL---NEM-NKMELSIEVCS--SMPSE-L-MNDLEQ
NGAVLSI-----------------GL-----------DPK--QDHPGEDSPAEVGGEDKS
TFSENPENASPKKEGSGEKSFQLPAFFSGLRVLKKGATSEGEETITEIKPKDSDLALLKL
TQPVQKSRVLPGTLSRKSGEKTSDLKATPTLLEQISQLLNIDMPKTEQKGEVCEQAKEE-
-EMG---SDTDQESQCKT-EVP----------SQN-EEVKPKPPETALEAFKALFMRPPK
KG-----STADTSELE-----AIKRKMRHEKESLRAVFERSKSRS-GDGSSDSRSADQSP
TEQDDRTPGRLQAVWPPPKTKDEEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RVFHIRGEHAVITARLEETIENLKCELEHRLSGGCDKTRDVCISTEDDNP--PKTFRNVY
IQTDRETFL--KHNEDESKTIKSNQIVPKKLNISSLNHISPP----NDNKDTTSIFQSLE
SCPSSQQ-Q-S----SPIPAPPLPI----------I-IPA--PPPLPPGLGPPP------
-SL--SQ-SSAGPPPPPPPPP-------------SLPLPISAGT------P-PPPPPLPI
PPPLPSTGPPP---PP--PPAPPGIGTPPPPPPFFGGNTSFSQIPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISGGSQSTTPTLW-DSLEEPDI---QDPSEFEYLFS-KDTIQQKKKPLSESFEKK
TKVKKIVKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLEALYENRAQK
DELIKIRKHYETSKEEELKLLDKPEQFLYELAQIPNFAERAQCIIFRSVFSEGITSVHRK
VEIITRASKGLLDMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDS------------------------------------EAGTEK
SIFPLPEPQDFFLAAQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVIVCKESPKEHLQPFKDKLEVFFQKAK-GEHKMEETHLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQETVNKLTAEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

----------------------------------------------MENVDNSLAGSDVL
--------------EPAKPEAGLE---------VAQSILSKFSMKSLFGFTSKLE-----
----SVNPEEKDAVLKAFH----SLDADPTSQRD-----DPSNGLDPREAESQVSPDLGN
DEKTARV-------ETES-EGSQRKE-AG-----TSL---LAQELLPL-----STWKGTK
DDVLCVRGTLVHTTS---------------------------------------------
--DSDS--------DDGGQE---PEEGSSTHGPKSPS--VVLSEPSQESQENPGGFRED-
-TV-TGEMN--GAELCAEDPQR--------IPPEISSRLEA---GNG-------------
-GLQTEYRPSQGQVGEEGSRVLPAVTSQNSSVGVTESASSKKETSGEKSFQLPAFFS---
-GLRVLKKGATAEGGETITEIKP--K---DGDLALLRLTQPVQK--SLVQA-G-PQTVKS
------------------------------------------------------------
---------------EEKAAEPKATP---TLL-----E--QLSLLLNI-DIP--------
--------------------------K------------------TEPKGADPESPRREE
MGCN---A--DQESQSDPGVAP----------TQG-GEVKPKPPETALEAFK--ALFI--
-R-----PPRKGTTADTSELEALKRKMRHEKESLRAVF-ERSKSKPADGSSDSKSADHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVVTARLEETIENLKHELEHRWRGGCEERRDVCISTNDDCP--PKTFRNVC
IQTDRQTFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GTASNQQ-KALP----LPTAPPLPA-----------PIPP--PPPLPLGLDSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLP--------LSSSAGPPPPPP---PPPPPPPLPN
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETFEKK
SKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEILTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAR-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGAVTLDRSSKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELLVSLAPED--DCFQSAGDWQGELPVGPPSKRS-----THGN-KKPRRSG-------GR
RESAGAL----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPNLWVLEE
RGNLL-NGALASSLQ-RRESCPPDIPKTPDTDLSLGNFETAFKDTGLG--REVLPPD--C
SSPEVG--------GDGVRR---PPSSGL----QHQQ--TGLSESHQDPEKHPEAE----
----KDEMEKPAKQTCKQIPVSKVVAKVQDLSSQVQRVVKTHSKGKAR--------IAIC
PAAHAEFVPKADLLTLPG-----------AEVGAHGSRRRGKERQGDGSSQSPARETATI
SSASACAQGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHT--SIPHT-R-PETRNK
RRTGLSL-----SGHKSLFLDLPHKV-----------GLDSSQPRGDKKKPCPPAPAALG
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFS----ADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPSRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDAEEKVGLKYTEAEYHAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVITARLEETIENLKHELEHRWRGGCEERRDVCISTNDDCP--PKTFRNVC
IQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GMASNQQ-KALP----PPPAPPFAG-----------PPPP--------------------
------------PPPPPPPPPPPPP----------TSSASK---LLR---PPTPTPSFLT
APAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1534)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSESFEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLE--------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

MEGTYCTLQLHNPVTELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDLFFKQTPTKDILTELYKLTAERERLLDSLLRSEHILGISMGNQEGNLQ
ELSVSLAPEE--DCFLSAGNRSRELPVNSLIRRS-----TQGS-KKPRRSG-------KR
RESPEEL----RQKRTRR-KGRGRQE-SAPPMGKDQV---CSSSSLPPPRVRPNLRLLEE
RGNLVPRETLTSSPRRRRESCPASILRTPDADLGFGSSGKTSEDTEH---EGPLSPD--S
SLAEVG--------VAG--I---GRQLKSPLEQEPP-------CLPESHEKHPGAERGG-
-TP----KPKSLERTCRKKPVSKVVAKVQEPSAQVQRVVRAHPDGEGR--------VAFC
SETQTEFIPKADFLIISG-----------AKDETQSSRRLGEEQQRVKSLQPLAAERASI
PREAASTEGAVNKVLRKVIESEK--L---DEATEGKTLGFSLNT--RATHT-F-PETRRQ
RKTGLPQ-----STHKFLLLDLPHTV-----------GPDSPQPKCDERKPSPQAPTALG
MVF----NNSSPQSSAHKRLSPVPSPVSPRCP-----SPQQHHRILLLPPLPSEGEAVFN
ECPSRKNLVSSGFPSAVTLEPSSSTKV------------------TETKGGTPTSLRASQ
TWLV---SEEAPERSLRPE--K----------ITA-PPQYQPPPGITSEGFPCDSFNE--
-Q-----TANDLPNKDGG---AWVLGYRAGPPCPFVLHEEREKSN-RSELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQSAILHLKREHKEEIENLQAQFEL
KTFHIRGEHALITARLEETIENLKQQLDQRWGGGCEEMRDACISTNDDCP--PKTFRNVY
IQTDRQTFL--KPCEGENKATRNNQIVPKKLNIS-LTQLSPT----KDSKDSLAPLQTEE
GISSSLQ-KKSPPPSTPPPPPP-------------PPIPP--PPPLPTGLGPLPP----P
APP--ISPVSAGPPPPPPPPPPPPP----------LPPSAGPPP------P-PPPPPLPN
VLALPNSGGLPPPPP---PPPPPGLAPPPPPGLSFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQDATPTLW-DSLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSESYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELTRIRKYYETSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGVTALHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYGLEILPKLKDVKSRDN
GMNLVDYVVRYYLRYYDQVGNKKMEG--KRLLSLSLQVSVDPS-----LPRDQMEAGTDK
SVFPLPEPQDFFLASQVKFEDLVKDLRKLKRQLEG-------------------------
---NGIIF-----------------NHNYFSSTAK-KEHKMEESHLENAQKSFEATVDYF
GMKPKTGEKEITPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLVSHVFHHDL----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MKCKDLLLHCNFYFH

PF02181 // ENSGT00870000136417_2_Domain_0 (1346, 1648)

RFLYELSQIPNFAERAQCIIFQSVFSEGITSVHRK
VDVITCVSKGLLGMKSVKEILGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDN
GINLVDYVVIYYLRHFDK------------------------------------DAGTDK
SIFPLPEPQDFFQASQVKFEDLIKDLRKLKRDLGA-------------------------
---HEKQMKIVCEESSEHHLQPFKDKLEEFFQKAE-EEHKTEENCLENAQKSFEETVGYF
GIKPKSGEKEVTPNYVFTVWYEFCSDFKTIWKRESKNISKERLKMAQQFVNKLTEEKKVE
TKKINPMASLKEKLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ILIFPNPTPRPNPS

PF02181 // ENSGT00870000136417_2_Domain_0 (1295, 1534)

AAIFQVDDSVVDLETLEALYENRAQQ
DELIRIQKHYETAKEEEVKLLDKPEQFLYELAQIPNFAERAQCIIFRSVFSEGIGAVHRK
VEIVTRASKGLLDMQSVRDILGLILAFGNYMNGGNRTRGQADGFSLEILPKLKDVKSRDN
GINLVDYVVTYYLRHYDE------------------------------------EAGTDK
SVFPLPDPQELFLAAQVKFEDLLKDLRKLKRQLEGKE-----------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----RSGMP--DCSQLLD----------LKSTAESDPDPLTT-LSVKTLF-------GF
TTEFESA----APKEETV------------------------------------------
----------------------------------------------LK-ALQPLPSN---
ISTHAN------------------------TWHERND--NGCNEDSE--NQHSVDSTSG-
-QA--------DPMSGRQAGLELELADQNELLLQHLRFVQ--PSL-----------SESD
NDDRDAILVQGTLVHTTS-----------DTESDTENKDLDTSENNGSKS--------GI
KDAALSAEALDNNNQ-NKEESESEGYSNSDDTVDTD--DIELHP--PFSKQ-LLREPDGI
--LQYDS-----NGKDKMLMDEQFTHLLAT-------GECPQELSDEEQRPS--------
-----VDNVSFQKAALAEKTFQLPAFFSGLRVRKKGLATEDGETVTEIKPRENDLALLKL
RQPVKKSSIASGLTIK---KKSSEPKANPTFLEQLSHLLNIDVSKNEDRTEDSGEGSGET
-EDS---DEAQENKASSKREPR----------FPS-EEIKSNPAESALDAFKALFTRPPK
KE-----TTADTSELE-----ALKRKMRNEKESLKAVFERSKSKP-GDGPS-DKSPDLSP
SEQDDKTPGRLQTVWPPPKANHEEVKVGLKYTEAEYQAAILHLKREHKEEIETLKSQFEL
RVFHIRGEHAVSTAQLEETIAHLKNELDNKLNRRNEKAKDIGVSTEDDNP--PKAYRNVC
IQTDRETFI--KPSEEENRAVKNNQIVPKKLNISSLTHSISA-Q--SENKD-NYNVQSSE
SVFSCQQ-KQMLPPPPPPPPPPPPPPPPLPCSSLSAVVPP--PPPLPMGPASLTSQFGSG
PPL--PPPLSEGCRNLQAPPPPPPP---------PL-PGLGPPV------P---------
-PPLPGSGLPP---P----------PPPPGPGLFFNSTLSSNQGPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPGRPMKPLY
WTRIQLQDNRKTAMPTLW-ESLEEPDI---LDTTEFEYLFS-KDTTQEKRKPLSETYEKK
TKAKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAILCVDDSVVDLETLEALYENRAQK
DELEKIKQYYQTSKVEELKLLDKPEQFLYELSQIPNFAERAQCIIFQSVFSEGITSVHRK
VDIVTRVSKALLSMKSVKEILGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDN
GINLVDYVVIYYLRHCDK------------------------------------EAGTDK
SIFPLPEPQDFFQASQVKFEDLIKDLRKLKRDLEA-------------------------
---SEKQMKLVCRESSEEHLQPFKEKLEEFFQKAK-EERKKEENSLENAQKCFEETVGYF
GIKPKPGEKEITPNYVFTVWYEFCSDFKTIWKRESKSISKERIKVAQQSVSKLTAEKKVE
TKKINPTASLKERLRQKEASVTAN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------ELLPL--------AALS
VVRDNVILVRGTLVNTTS---------------DSDSDDGGQEPEEGSNINGPKSPSG--
----VLSEPSEQSQEKPGDGRENTAP--------GERGDAEPSG--EGPQR-TLQEINSK
L--EPED-----GGLQT---------------E----HSPGQRQAGEEGSKVLPVVTDQN
SSVGVTENTSPKKEVPGEKSFQLPAFFSGLRVLKKGAPAEVGETITEIKPKDGDLALLKL
TQPVQRSLAQAGPQAVKMGEKTNDPKAAPTLLEQLSQLLNIDVPKAESKAEDPEQPRGE-
-ERS---GSTPQESQSGPGEAQ----------TQG-GEVKPKPPETTLEAFRALFIRPPK
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSRSRP-GDGPSDSKSPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVITARLEETIENLKYEIEHRWRGGCEEMRDVCVSTDDDCP--PKAFRNVC
IQTDRETFL--KPCEGEDRTTRSNQIIPRKLNISSLSQLSPP----NDSRDTSVPLQSAE
SISSSQQ-KATP---------P--AP---------AAIPP--PPPLPPALGPLPL----A
PPP--PP-VNTGPPPPPPPP---------------LPPSAGPPP------P-PPPPPLPH
ST----------------APPPPGPVPPPPPGLFFGVNPSASQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAVEPSCPMKPLY
WTRIQISDKSQNSTPTLW-DSLEEPDI---RDTSEFEYLFS-KDTPQQKKKPLSESYEKK
NKIKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITAVHRK
VEIITRASKGLLQMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMAVVCKESPREYLQPFKDRLKEFFQKAK-KEHTVEESHLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTAEKKVE
TKKINPTASL-------------------------------

MEGTHCTLQLHNPIAELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDIFFKQTPTKNILTELYKLTAEKERLLDSLLRSDNILGVSMGSQEGKLQ
ELSVILATGD--DYFQSAGNWRRELPVSSLIRRS-----TQEN-KKPRRSG-------RR
RESPEEL----RQKRTRR-KGRGCQE-SAFQMGKDQV---CSSSSLSF-RARPNLRLLEE
RGNLVPRGTLTS-SLRRRESCPANILRTPDADLAFGNSGRTSEDTDLE---GPLSPD--S
SPTEVG-------------DADVGGQLKSSHQQEPPQ--PNVSES---HGKHAGAERWSS
GTR----KSKSLERTCSKKPVSKVVAKIQEPSAPVKRIVRAHHDDKGR--------VAYG
PETQTEFIPKADFLTLPG-----------GETETHSSRRLEEEQPGS-----SAPERASI
TKEPVSTEAAVNKVLRKVIESEK--L---DEATEGKRLGFSLNT--RVTHT-F-PETRSQ
RKAGLPQ-----SGHKFLLLDLPHTV-----------GPDAPQPKCDEKKPTPQVPTALG
MVF----NNSSPQSSAHKRLSPVPSPLSPRCP-----SPQQHHRILLLPPLPSEGEVVFN
EYPSRKNDVSSGFPSADTLEPSSSTKV------------------TETKGASPTSLRASQ
TWLV---SEEASEKGLGPEKIT------------A-PPQHQLPPGIASEGFPCDNFKEQ-
-------TAKDLPNKDGG---VWVPGYRAGPPCPFLLHEEKEKTS-RSELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIETLQAQFEL
KTFHIRGEHALVTARLEEAIENLKQQLEKR-REGCEEMRDVCISTDDDCS--PKAFRNVC
IQTDRETFL--KPCDAESKATRSSQIVPKKLTIS-LTQLSPS----KDSKDIHAPLQTRE
GTSSSSQQKISPPAPPTPPPPPPPL----------IP--P--PPPLPPGLGPLPP----A
PP---IPPVCPVSPP----------PPPPPPPPTPVPPSDGLPPPP------PPPPPLPN
VPALPNSGGPPPPPP-PPPPPPPGLAPPPPPGLSFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQINDKSQDAAPTLW-DSLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSEAYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFTVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQ------------------------------------EAGTDK
SVFPLPEPQDFFLASQVKFEDLLKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPREYLQPFKDKLEEFFKKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKTGEKEVTPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVATN-----------------

------------------------------------------------------------
------------------------------------------------------------
--------ME--DVGDSLSGSDVAEPE-KSEAELEMAQSILSK-FSMKSLF-------GF
TSKLESV----KPEEE-----DAVLK-AFRSL----------------------------
---------------------------VVDPAPQLG---DPSNGSGLQEAEAQVPPD--F
G-------------KDG--K---T----------------ASVETEM------ES-EGS-
--Q----RKAEAGV------------------------SLPGQELLPL--------TALS
VSRDDVILVRGTLVNTTS---------------DSDSEDGGQEPEEGSNANGLKSP----
--SVVLSKPFEEPKDKPGECRENIAT---GE-----KGDAEPCA--DGPPG-TPPEIGSK
PELG--S-----GGFQT---------------E----HSPSQGPAGQEGSQVPPVVTDQN
LSVGVTENTSSKKEVPGEKSFQLPAFFSGLRVLKKGAPAEGGETITEIKPKDGDLALLKL
TQPVQKSLAQAGLQAVKTGEKTSDLKATPTLLQQLSQLLSIDMPRAELKAEDPEPPRGE-
-EMG---HSAAPESQSCPGATQ----------TQG-GEVKPKPPETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSRSRP-ADGPSDSKSPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVITARLEETIENLKHEIEHRWRGGCEEMRDVCISTDDDCP--PKTFRNVC
IQTDRETFL--KPCESEGKTTRSNQIIPKKLNISSLSQLSPP----NDNKDIHAPLQSVE
GISSSQQ-KAL----PPPPAPPLPA-----------AIPP--PPPLPPGLAPLPP----V
PPP--PPPVSAGPPPPLPP---------------PLPPSAGPPP------P-PPPPPLPN
LPALPNSGGP----PP--APTPPGLVPPPPPGLFFGVGP-SSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKXXXXXXXXX-XXXXXXXX---XXXXXXXXXXX-XXXXXXXXXXXXXXXXXX
XXXXXIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
EELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLVKDLRKLKRQLEA-------------------------
---SEKQMAVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

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------------------------------------------MPRAELKAEDPELLKEGD
MGCS-----ATQESQSGPGAQ-----------AQG-GEVKPKPPETALEAFKALFIRPPK
KG-----TTADSSEL-----EALKRKMRHEKESLRAVFERSKSRL-TDGPCDPKSSGHSL
TEQDDRTPGRLQAIWPPPKTKDTEEKVGLKYTEAEYQAAILHLKRKHKEEIENLQAQFEL
QAFHIRGEHAVLIARLEETIQHLKQELEHGWRGGCEEMRDACVSTDGDCP--PRTYRNVC
IQTDRETFL--KPCEGENKTTRSNQIIPKKLNISTLSQLSPP----NDNKDVHTPFQPVD
SISLNQQKTSSPPPAPPPP-----------------------PPPLSPGLELLPP----A
PPPPPLPLVSTGPPPPPPPPP----------LPPPLPPSSGPPP-------PPPPPPLPN
CPPPPNSGGLPP------APGPPGLAPPPPPGLFFGVSPSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1695)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDTMQQKKKPLSETYEKK
NKAKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRGQE
DELVKIRKYYETSKKEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILGLILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------XXXX--
----------XXXXXXXXXXXXXXXX---XXXXXX-------------------------
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXK-KEHKTEVSHLENAQKXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEKLKRAQESVSKLTAEKKVE
TKKINPTASLKERLRQKEASVTTS-----------------

MEGTHCTLQLRKPITELCYISFYLPRGEVRGFSYKGTVILDRSNKGFHNCYQVREGSDTI
SLSQQLNELPGDIFFKPTTTKDILTELYKLTAERERLLANLRSSDHILGISMGNQEGKLL
ELSVSVAPED--SCSQSAGNWWREPSAGPLTQRS-----THGN-KKPRRFE-------GR
RESIEV------QKRTRR-KGRGRQQ-STPQMGKDQI---CPSNCLPPSGARLNLRLLEE
RGNLVPNGVLTCSLQ-RRESCPADIPRTPDADLGFASSGMASGNTGLG--KGALPPR--S
SSTEAG--------DDG--V---RVLPRKPHRLEHQH--TGLPESQEDAKKHPEAQRG--
--G----LGKLAERTCRKRPISKVVAKVQDLSTQVQRVVNVPPEGEEK--------IAVY
PEVKAEFICKVDLLTLPG-----------AEAGAHGSRWQSKKQQGARSSQLPARESASV
SSLSASTDRAVNKVLLKVIESEK--L---DGATQGKRLGVPLNT--RATHS-L-PETRSK
RKAGVPQ-----RGHKSLFLDLPCTT-----------GPDSSHCRGDERRPSPSVPVAPG
MGF-----NNSSQQPRHQQPPPAPSPLYPRCP-----SPQQHHRILPIPPLPSEREAAVN
DSPGRQSSIFSESSSPDTLEPPSSAEV------------------TETKGASAASLTAGQ
PHLV---PGETSEKSLGPG--K----------TTA-QPQQQAPPGVSSEGFPWDRFSE--
-Q-----TAKDLPSRDGG---AWVLGYRAGPPCPFLLYEDREKSN-RSKLYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAAITARLEETIENLKLQLEQRWRGGCEELRDACVSTDDSCA--PKAYRNVC
IQTDRQSFL--KPCEGDTKTPRSNQIVPRKLNISSLSQLSPP----NDNKDTHAPLQNGE
SISPSHP-KTAPPPPPPP--PP-------------LPIPP--PPPLPPGPGALPP----M
PPT--PA-LSASPPPPPPPPPPPPP----------LPPSAGPPP--------PPPPPLPN
PQAVPGSGAPP---P---APAPLGLVPPPPPGLFFGLSPSSSQAPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSRPMKPLY
WTRIQISDG-QSAAPTLW-DSLEEPDI---RDTSEFEYLFS-KVTTPQKKKPLSETYAEK
NKVKKIIKLLNGKR-SQAVGILISSLHLEMKDIHQAIFNVDDSVVDLETLEALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGVTSLHLK
VDIVTRASKGLLHMKSVKDILAIILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQVGNGIMWE--TALMGFNSYSFLAFSIHTNRESLKGRYSGTEK
SVFPLPEPQDFFLASQVKFEDLSEDLKKLKKQLEA-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFQTTVGYF
GMKPKAGEKEVTPGYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQALVSKLTSEKKVE
TKKINPTASLKERLCQKEASMNAN-----------------

MEGTHCTLQLHKPIAELCYISFYLPKGEVRGFSYKGAVTLDRSKKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED-D-CFQSAGDWQGELPVGPPNKRS-----THGN-KKPRRSG-------GR
RESAGAV----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPNLWVLEE
RGNLLPNGALASSLQ-RRESCPPDIPKTPDTDLSLGSFETAFKDTGLG--REVLPPD--C
SSPETG--------GDGARR---PPSGLEH-----QQ--AGLSESHQDPEKRPEAE----
----KDEMEKPAKQTCKQIPVSKVVAKVQDLSSQVQRVVKAHSKGKAR--------IAIC
PAAHAEFVPKADLLTLPG-----------AEVGAHGSRRQGKERQGDGSSQSPARETASS
SSASACAQGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHR--SVPHT-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPCPPAPAALG
NVF----NNSASQSSTHKRTSPVPSPLSPRLS-----SPQLHHRILRLPALPGERETALN
DSPGRKSRVFS----ADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVVTARLEETIENLKHELEHRWRGGCEERRDVCISTNDDCP--PKTFRNVC
IQTDRQTFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GAASNQQ-KALS----LPAAPPLPA-----------PIPP--PPPLPLGLDSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLP--------LSSSAGPPPPPP---PPPPPPPLPN
SPAPPNPGGPPP------APPPPGLAPPPPPGPFFELGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETFEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAR-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHKPITELCYISFCLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDII
SLSQEPDEHPGDLFFKQTPTKDILTELYKLTTERERLLTNLLSSDHVLGITMGNQEGKLQ
ELSVSLAPED--DCFQSAGDWQGELPVGPLNKRS-----THGN-KKPRRSG-------GR
RESFGAL----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPNLWVLEE
KGNLLPNGAPASSLQ-RRESCPPDIPKTPDTDLGFGSFETAFKDTGLG--REVLPPD--C
SSTEAG--------GDGIRR---PPSGL-----EHQQ--TGSSESHQDPEKHPEAE----
----KDEMEKPAKRTCKQKPVSKVVAKVQDLSSQVQRVVKTHSKGKET--------IAIR
PAAHAEFVPKADLLTLPG-----------AEAGAHGSRRQGKERQGDGSSQSPAGETASV
SSVSASAEGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHT--SVPHT-R-PETRNK
RRAGLPL-----GGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPSPPAPAALG
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFSGCVSADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCP--PKTFRNVC
VQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GMASNQQ-KALP----PPPAPPLPA-----------SIPP--PPPLPSGLGSLSP----A
PPM--PP-VSAGPPPPPPPPPPPPPLP--------PPSSAGPPP-------PPPPPPLPN
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQSATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDI-
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLADLLSSDHILGITMGNQEGKLP
ELSVSLAPED--DCFQSAGNWQGELPVGPLNKKS-----THGN-KKPRRFG-------GR
RESFGAL----PQKRTRR-KGRGGRE-SAPLMGKDQI---CSSNSLPLSRTRPNHWLLEE
RGNLLPNGALDSSLQ-RRESCPPDIPKAPDTDLGFGSFA--FKDTGLG--REVLPPD--C
SSTEAG--------EDG--F------RRLPSGLEHQQ--TGLSESPQDPEKHPEA-EKD-
--E----MQKPAKRTCKQKPVSKVVAKVQNLSSQVQRVVKTHSKGEER--------IAIC
PEAQAVFVPKADLLTLPG-----------AEAGARGSRRRGKEREGNGSLKSPATEAASI
SSAPTSAEGAVNKVLLKVIESEK--L---DEAPEGKRLGFPFHT--SVPHT-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQLRGDDKKPPPPAPAALG
KVF----NNSSSQSSTHKQTLPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFPGCVSADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PQLV---PGEPLEKSSGPG--K----------TTA-KSQHQSPPGISSESFPWDCFNE--
-Q-----TLKDLPNRDGG---TWVLDYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLRYTEAEYQAAILHLKREHKEEIENLQAQFEL
QTFHIRGEHAAITARLEETIENLKHELEHRWRGGCEERKDACISTEDDCP--PKTYRNVC
IQTDRETFL--KPSEGESKTTRSNQLVPKKLNISSLSQLSPP----NDNKDIHAALQPME
GSESNLQ-RAP----PPPPAPPLPA-----------SIPP--PPPLPPGLGSLSP----A
PPM--PP-VSAGPPPPPPPPPPPPPLPPP--------SSVGP-P------PPPPPPPLPN
FPAPPKAGGP----PP--APTPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNAAPTLW-DSLEEPDI---QDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSIFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVNTN-----------------

MEGTHCTLQLHKPITELCYISFYLPRGEVRGFSYKGTVTLDRSNKGFHNCYQVREGSDII
SLSRQPNEHPGDIFFKQTPTKDILTELYKLTAERERLLADLLSSDHILGITMGNQEGKLP
ELSVSLAPED--DCFQSAGGWQGELPVGSLNKRS-----THGN-RKPRRFG-------GR
RERFEEL----PQKRTRR-KGRGGQE-AASHMGKEQV---CPSSSLPS-RVEPQLRLVEQ
RADLFSNGVLTSPPH-RRESCPPDILGMLDTDVGFGS-------SGLG--RGVQPPN--Y
SSTEAE---------DG--V---EGPLRWPPGLQHHQ--IGLPESQKDPEKHPEV-VER-
-AR----TKKSAEWACRTKPVCKVVAQVQDLSAQVQRVVTTPPEAEEG--------NVLG
PAPQADFIPRAELLTPSG---------------TQSPRHWGKEREHESS-QP------SA
RDSVSDTEGAVNKVLLKGTESEK--L---DEATEEKRLGLSLSK--RAPHG-L-PGTRSK
KRAVPCR-----------------SF-----------GPDSPHLQDGNRRPSPPASAALG
TVF----NNSSPQSGTHTRTSPVPSPLSPRRP-----SPQQHHRILRLAPLPGEREAALH
DSAGRKSGVFPGSSSADTLEPPSSAKV------------------TETKGASPASLRAGQ
APLV---PEEPLEKSLGPG--K----------TTA-GLQPPSPPGTSADGLPWDCFSE--
-Q-----TTKDLPNRDGS---AWVLGYRTGPACPFLLHEEREKPN-RSELYLDLHSDQSP
TEQDDRTPGRLQAVWPPPKTKDAEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAKFEL
EAFHIRGEHAVITTRLEETIENLKQELEHRWRGGCEEMRDVCISTDDDCP--PKTYRNVC
IQTDRETFL--KPCEGESKTTRSNPVIPKKLNITSLTQLSPP----SDSKDIHAPLQSVE
GISSNQQ-KTS----TPPPAPPLPAP---------P-IPP--PPPLLPSLDPLPP----A
HPS--PP-VSAGPPPPPPPPPPPPPPPPPPPLPPALPPSAGPPP------P-PPPPPLPN
SPALTNNEGP----PP--APAPPGLVPPPPPGLFFGLTSSSSQSPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDATQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQHAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFHRAK-KEHKMEETHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHKPIAELCYISFYLPKGEVRGFSYKGAVTLDRSKKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED-D-CFQSAGDWQGELPVGPPNKRS-----THGN-KKPRRSG-------GR
RESAGAL----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPNLWVLEE
RGNLLPNGALASSLQ-RRESCPPDIPKTPDTDLSLGTFETAFKDTGLG--REVLPPD--C
SSPEAG--------GDGARR---PPSGLEH-----QQ--AGFSESHQDPEKRPEAE----
----KDEMEKPAKQTCKQIPVSKVVAKVQDLSSQVQRVVKAHSKGKAR--------IAIC
PAAHAEFVPKADLLTLPG-----------AEVGAHGSRRRGKERQGDGSSQSPARETASS
SSASACAQGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHR--SVPHT-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPCPPAPAALG
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQLHHRILRLPALPGEREAALN
DSPGRKSRVFS----ADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVVTAGLEETIKNLKHELEHRWRGGCEERRDVCISTNDDCP--PKTFRNVC
IQTDRQTFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GTASNQQ-KALP----LPTTPPLPA-----------PIPP--PPPLPPGLDSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLP--------LSSSAGPPPPPP---PPPPPPPLPS
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETFEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAR-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLRKPITEVCYISFYLPRGEVRGFSYKDTVTLDRASKGFHNCYQVREGSDLH
SLSRQPNEHPGDIFFKPTPTKDILTELYKLTAERERLLAGLLSSGHILGITMGNQEGKLP
ELSVSLASED--DCFQSAGDWLGEPSVGCLNKRS-----SHGN-KKARRFG-------GR
RESFEGS----LQKRTKR-KGHGGQE-LAPLRGKDQA---YFSSSLPLSRTRSHLWLLEE
RGNLLLNGELTSSLQ-RRERCTLEAPRTLDADSALGSIKKPSEDAGLG--RGGLPPD--C
SSTEPG--------DDR--A----------TELVHQQ--TGLTESHKEPEKEPAA-ERR-
--R----RAKAAEWTHRKKPVSRVVARVQDLPTQVQRVVKTHPEGEGK--------IAPG
LAAPAEFTPGADLLTLPG-----------AEAGAWGARGLDQEQQRDRSWQPSAGECP--
---PASTEGAVNKVLLKVIESEK--L---DAAAEGKRLGFPFGT--VGAHT-L-PETRSR
RGAGLGR-----GSRKTSFLDLPRGG------V----DPGS-----DEKRLPPLALAAPG
TVI----NNSAFPPSTRKRMSPVPSPLSPRLP-----SPQQHHRILRLSSPPGEREATLD
DSLSGRSRAFSGSLSADTLEPPSSAKV------------------TETKGASSTSLRVGQ
PRLV---PGEPLEKTLGPG--R----------TTA-QPQHQSPPGISSEGFPRDGFSEQ-
-T-----TAKDLPSKDGG---AWVLAYRAGPACPFLLQEEREKPN-RNELHLDLHPDHSP
TEQDDRIPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVITARLEETIENLKHEIEHRWQGGCEEMRDVCVSTDDDCP--PKTFRNVC
IQTDRETFL--KPCEGEGKTTRSNQIIPKKLNISSLSQLSPP----NDNKDTCVPP--AE
GSSLNQQ-KVPPSPPPPPPAPPLPA----------A-IPP--PPPLQPGLGPLPP----A
PPP--PP-VNTGPPPPPPPP---------------LPPSAGPPL------P-PPPPPPPP
SIPLPNNGGP----PP--APALPGLAPPPPPGLFFGVGPSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNSTPTLW-DSLEEPDI---RDTSEFEYLFS-KDIPQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQILTAHF-----CVCFPSISTQRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITALHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQVRNGIQSI--NGKSLGKMLSGVPLNYP--QRQSFSSEAGTEK
SVFPLPEPQDFFLASQVKFEDLTKDLRKLKRQLEA-------------------------
---SEKQMAVVCKESPKEYLQPFKDSLEEFFQKAK-KEHKMEESYLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTAEKKVE
TKKINPTASLKERLRQKEASVSTN-----------------

MEGTHCTLQLHKPITELCYISFYLPRGEVRGFSYKGTVTLDRSSKGFHNCYQVREGPDIV
SLSQEPSEHPGDIFFKQTPTKDILTELYKLTTERERLLANLLSSDHILGITMGNHEGKLP
ELSVSLASED--DCFQSAGEWPGELPVGSLNKRS-----AHRN-KKARRFG-------GR
RENFEAL----LQKRTRR-KGHGGQE-SAPQMGKDQI---CFSNSLPRSQARPNLWLLEE
RGNLLPNGALTSSLQ-RRESCPPDISRTLEADLGFGNFGTASKDTGLG--RGTPPAD--F
SSTESG--------DGG--I---LEPLRRPHGLEHQQ--TGLPGSHQDPEKHPEA-KRE-
--G----TEKWAERTCEKKPVSKVVAKVQDLSSQVQRVVKTHPEAEET--------IAIC
PAAQVEFIPKVDLLTLPV-----------AEAGVRGPRRQGKEQQGHGPLQSSASERASI
STASASAEGAVNKVLLKVIESE--KL---DEATEGKRLGFPLSK--TATHT-V-PETRSK
KRAGLPP-----SGCKSLFLDLPHGV-----------DTGSSQPRGNEKRPSLPAPAAHG
VAF----NNSSPQSSTRKRTSPVPSPLSPRVP-----SPQQHRRILQLPPLPGEREAALN
DSPGRKSGVFSGSPFADTLEPPSSTKV------------------TETKGASPVSLRAGQ
PRLA---PGETLEKSVGPE--R----------TTA-QPQHQSPPGISSEGFPWDSFND--
-H-----RPKDLPNRDGS---TWVLGYRTGPACPFLLHEEREKSN-RSELYLDLHPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAGILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVVTARLEETIENLKHELEHRWRGGCEERRDVCISTDDDYP--PKTYRNVC
IQTDRDTFL--KPCEGESKTTRSNQIVPKKLNISSLGQLSPP----NDSKDIHTSLQSVE
GMSSNQK--TS----PPPPAPPLPA----------S-IPP--PPPLPPGLGPLSP----A
PPT--PP-ASAGLPLPPPPPP--------------LPPSAGPPP------P-PPPPPLPN
SLVLPNPGGP----PP--APAPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLY
WTRIQI

PF02181 // ENSGT00870000136417_2_Domain_0 (1207, 1648)

SD----------------------------------------------------
----RIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEV-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEEGHLENAQKSFETTVGYF
GMKPKSGEKDITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTS-----------------

MEGTHTILQLHKPIMELCYVSFYLPEGKVRGFTYKGCVTLDRTSKRFCNCYKVQERSEM-
EMREQPYENFGDIIFKQTTTKDILIELYRLTAEKEKLLSSLLRSHHIPSLDTGQQEGKQQ
AVSGVQKHRG--DDYSSFT-YRQEFFLDS-------TSSDNFN-CKKKSKY-------RK
KESFEEF----RHWKGTKKIGQGIHL-GNQKMPPTR----FPIRSFPSSFSASSCLIVK-
----------------GKDDLPLEIGIQPEREREDGYFLESNKVMKLD---ANLPS---C
VSKDSNDMVPVELLDNGECILEVKNVQQSIALVEPSQ--DNLSNQLETLSK-PA------
--AAKSLKDKCTEQVCKEKAAIGVVVKVQDSEACLKKATQTHAESLSDFHKGKETASPNL
TAVPNEFISRTDVYSVDE-----------AAGDSKNSVQQ--EEERDGSVLQYKAERVHI
TDESCNPVGAVNKALLKVIRSDS--L---DEAAEWKRLQQIT----AAD-R-NLPGSIYE
KRTTVSR-----GSSKHLFLNLPVSEGLDVS-------QTGNNLKLEEKRLHSPSLIAVS
NVF----SNSYPLSNTHKQMSPIPSPLSSRLP-----SPQLHHRILPLPAQNGKDEPMFG
DYCSGRHGAINL--SFNDLEPQFYLKF--------SEPGEL-------------GFAIRQ
PGLHQNATAGHFEKRTLQGRFT----------TRT-PQNFCPESVSSTNGFPNDDFTER-
-L-----TNLDVSNRDED---TWVLDCRLGQSSEK----EKINRN-VLHLSLELNPDLSP
SEQDDKTPGRLQTVWPPPKANHEEVKVGLKYTEAEYQAAILHLKREHKEEIETLKSQFEL
RVFHIRGEHAVSTAQLEETIAHLKNELDNKLNRRNEEAKDIAVSTEDDNP--PKTYRNVC
IQTDRETFI--KPNEEENRAVKNNQIVPRKLNISSLTHCISS-Q--SENKD-NYNIPVSE
SVLSCQP-KQMLPD------SSLP-----------GLVPP--PPPLPTGLTTPTLQFGSG
PPL--PPPVSEGCRDFQLGPPVA-------------------------------------
-PPLPGSGLPPP-------------PPPPGPGFFFNSTLSSSQGPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSRPMKPLY
WTRIQLQGTRKTAIPTLW-ESLEEPDI---LDTTEFEYLFS-KDTTQEKRKPLSETYEKK
NKAKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAILCVDDSVVDLETLEALYENRAQK
DELEKIKQYYQTSKEEELKLLDKPEQFLYELSQIPNFTERAQCIIFQSVFSEGITSVHRK
VDIITRVSKALLNMTSVKEILGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDN
RINLVDYVVIYYLRHCDK------------------------------------EAGTDK
SIFPLPEPQDFFQASQVKFEDLIKDLRKLKRDLEA-------------------------
---SEKQMKLVCRESSEEHLQPFKEKLEEFFQKAK-EERKKEESSLENAQKYFEETVGYF
GIKPKPGEKEITPNYVFTVWYEFCSDFKTIWKRESKSISKERIKVAQQSVSKLTAEKKVE
TKKINPTASLKERLRQKEANVTVN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----DVILVRGTLHTTS----------------DSDSDDGDQDPDGSISHGK------T-
---VSVSEPSQQREEIPGDSREKIAT---GEP-DSGKFCAEGLQ--RSPRE-I-SAKSEP
SDGGLQG-----------------EH-----------SPN--QDQAGEDSLIPPAVTSHN
SRAGITESASSKKEVPGEKTFQLPAFFSGLRVLKKGVTAEGGETITEIKPKDGDLALLKL
TQPVQKSLAQTGPLTLKNGEKTTEVKATPTLLEQLSQLLSIDLPKTELKAEDLEPSRGE-
-EMG---CSVDQESQSGPGEAQ----------TRG-GEVKPKPPETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMRQEKESLRAVFERSNSRP-AEGPSDSKSPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFRIRGEHAAITARLEETIENLQHELEHRWQGGCEEMRDACVSTDDDYL--PKTYRNVC
IQTDRETFL--KPCEGESKTTRSNQIVPKKLNISSLSQLSPP----SDNKDIHAPLQSVE
GISSNQQ-KVS----PPPPAPPLPV----------P-IPP--PPPLPPGLESLPP----A
PPT--AP-GSAGLPPPPPPPP-------------PLPPSAGPPP------P-PPPPPLPN
LPPLPSSGGPP---PP--PT------PPPPPGLFFGVGSPSSQYPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXFLHELAQIPSFAERAQCIIFRSVFSESITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDT
GINLVDYVVKYYLRYYDQ------------------------------------XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPSASLKERLRQKEASVATS-----------------

MEGTHCTLQLHNSITELCYISFYLPKGEVRGFSYKGAVTLDRSNNAFHNCYQVREGPDIT
SLSQQPKEHPGDIFFKQIPTRDILTELYKLTAERERLLDSLLRSDHILGISMGNQEGKLQ
ELSVSLARED--DCFQSAGSWNRELI----------RRSTQGN-KKPRRSG-------RR
RDSPEEL----WQKRTRR-KGRGQQESSAPGMGKDQV---CSSSSLPPSRVRPNLRLLEE
RGNLVPQGTLTSSPRRRRESCPANILRTPDADLGFGSSGRTSEDTDLE---GPLSSN--G
SPTEVG--------DAG--I---GRQLKSPREREPP----SLPES---HEKHSGAERVG-
-TR----KSKSLERTCRKKPVSKVVAKVQELSAEVQRVVRAHPDGEGR--------VAFC
SETQTEFISKADFLILPG-----------AKDETQSSRRLGEEQQGVKSLQPQATERASI
PSEPAINEGAVNKVLWKVIESEK--L---DEATEGKTLGFSLNT--RATHT-F-SQTGSQ
RKAGLSQ-----SGHKFLLLDLPHTG-----------GPDSPQPKCDERKPIPQTPTALS
MVF----NNSSPQSSAHKRLSPVPSPLSPRCP-----SPQQHHRILPLPPLPSEGEAVFN
ECPSRKNGVSSGFPSAVTLEPSSSTKV------------------TETKGGSPTSLRASQ
TWLL---SEEPSEKSLRPE--K----------ISA-APQHQPPPGITSEGFPCDSFNE--
-Q-----TAKDLPNKDGG---AWVLGYRAGPPCPYLLHEEREKSS-RSELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
KTFHIRGEHALITARLEETIENLKQQLDHRWGGGCEEMRDACISTEDDCP--PKAFRNVC
IQTDRETFL--KPCESESKTTRSNQIVPKKLNIS-LAQLSPT----KDSKDIHAPLETVE
GSSSSQQ-KISP----PPPTPPLAP----------PPIPP--PPPLPTGPGPLPP----A
PPX--XX------------------------------------X------P-PPPPPLPN
VLALPNSGGPP---PP-PPPPPPGLAPPPPPGLSFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1611)

KPAIEPSCPMKPLY
WTRIQISDKSQDATPTLW-DSLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGVTSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQ------------------------------------EAGTDK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPKEYLQPFKDKLEDFFQKAK-KEHKMEESHLENAQKR--------
------------------------------------------------------------
-----------------------------------------

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---------------------------------------KME

PF02181 // ENSGT00870000136417_2_Domain_1 (1603, 1648)

EGHLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKNISKER------------------
-----------------------------------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLADLLSSDHILGITMGNQEGKLP
ELSVSLAPED--DCFQSAGNWQGELPVGPLNKRS-----THGN-KKPRRFG-------GR
RESFGAL----PQKRTRR-KGRGCRE-SAPLMGKDQI---CSSNSLPLSRTRPNHWLLEE
RGNLLPNGALDSSLQ-RRESCPPDISRTPDTDLGFGSFETAFKDTGLG--REVLPPD--C
SSTEAG--------ENG--F------RRLPSGLEHQQ--TGLSENHQDREKHPES-EKD-
--K----MQKPTKQTCKQKPVSKVVAKVQDLSSQVQRVVKTHSKGKER--------IAIC
PEAQAEFVPKADLLTLLG-----------AEAGARGSRRRGKERQGNGSLKSPAREAASI
SSAPASAKGAVNKVLLKVIESEK--L---DEAPEGKRLGFPFHT--SVPHT-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQLRGDDKKSSPPAPAALG
KVF----NNSSSQSSTQKQTLPVPSPLSPRLH-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFPGCVSADSLEPPSSAKV------------------TETKGDSPAFLRAGQ
PRLV---PGESLEKSLGPG--K----------TTA-EPQHQSPPGISSESFPWDGFNE--
-Q-----TLKDLPNRDGG---TWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLRYTEAEYQAAILHLKREHKEEIENLQAQFEL
RTFHIRGEHAVITARLEETIENLKHELEHRWRGGCEERKDACISTDDDCP--PKTYRNVC
IQTDRETFL--KPSEGESKTTRSNQLVPKKLNISSLSQLSPT----NDHKDIHAALQPME
GTESNQQ-KAP----PPPPAPPLPA-----------FIPP--PPPLPPGLGSLSP----A
PPM--PP-VSAGPPPPPPPPPPPPPLPPP--------SSVGPPP-------PPPPPPLPN
FPAPPNPGGP----PP--APTPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNAAPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSIFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVNTN-----------------

MEGTHCTLQLHNSITELCYISFYLPKGEVRGFSYKGAVTLDRSNNAFHNCYQVREGPDIT
SLSQQPKEHPGDIFFKQIPTRDILTELYKLTAERERLLDSLLRSDHILGISMGNQEGKLQ
ELSVSLARED--DCFQSAGSWNRELI----------RRSTQGN-KKPRRSG-------RR
RDSPEEL----WQKRTRR-KGRGQQESSAPGMGKDQV---CSSSSLPPSRVRPNLRLLEE
RGNLVPQGTLTSSPRRRRESCPANILRTPDADLGFGSSGRTSEDTDLE---GPLSSN--G
SPTEVG--------DAG--I---GRQLKSPREREPP----SLPES---HEKHSGAERVG-
-TR----KSKSLERTCRKKPVSKVVAKVQELSAEVQRVVRAHPDGEGR--------VAFC
SETQTEFISKADFLILPG-----------AKDETQSSRRLGEEQQGVKSLQPQATERASI
PSEPAINEGAVNKVLWKVIESEK--L---DEATEGKTLGFSLNT--RATHT-F-SQTGSQ
RKAGLSQ-----SGHKFLLLDLPHTG-----------GPDSPQPKCDERKPIPQTPTALS
MVF----NNSSPQSSAHKRLSPVPSPLSPRCP-----SPQQHHRILPLPPLPSEGEAVFN
ECPSRKNGVSSGFPSAVTLEPSSSTKV------------------TETKGGSPTSLRASQ
TWLL---SEEPSEKSLRPE--K----------ISA-APQHQPPPGITSEGFPCDSFNE--
-Q-----TAKDLPNKDGG---AWVLGYRAGPPCPYLLHEEREKSS-RSELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
KTFHIRGEHALITARLEETIENLKQQLDHRWGGGCEEMRDACISTEVDCP--PKAFRNVC
IQTDRETFL--KPCESESKTTRSNQIVPKKLNIS-LAQLSPT----KDSKDIHAPLETVE
GSSSSQQ-KISP----PPPTPPLAP----------PPIPP--PPPLPTGPGPLPP----A
PPI--SP-VSAGPPPPPPPPPPPPP----------LPPSAGPPP------P-PPPPPLPN
VLALPNSGGPP---PP-PPPPPPGLAPPPPPGLSFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQDATPTLW-DSLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGVTSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQ------------------------------------EAGTDK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPKEYLQPFKDKLEDFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKTGEKEITPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKIE
TKKINPTASLKERLRQKEASVATS-----------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGAVTLDRSSKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPQD--DCFQSAGDWQGELPVGPPSKRS-----THGN-KKPRRSG-------GR
RESAGAL----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPHLWVLEE
RGNLLPNGALASSLQ-RTESCPPDIPKTPDTDLSLGNFERAFKDTGLG--RGVLPPD--C
SSPEAG--------GDGVRR---PPSSGL----QHQQ--TGLSESHQDPEKRPEAE----
----KDEMEKPAKQTCKQIPVSKVVAKVQDLSSQVQRVVKTHSKGKAR--------IAIC
PAAHAEFVPKADLLTLPG-----------AEVGAHGSRRRGKERQRDGASQSPARETASI
SSASACAQGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHT--SVPHT-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPCPPAPAALG
KVL----NNSAPQSSTHKRTSPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGTKSRVFS----ADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLA---PREPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYHAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVITARLEETIENLKHELEHRWRGGCEERRDVCISTNDDCP--PKTFRNVC
IQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GMASNQQ-KALP----PPPAPPLPT-----------SIPP--PPPLPLGLGSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLX--------XXXXXXX--------------XXXX
XXXXXNPGVPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETFEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAR-KEHKTEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
------MEGGNAGCSRQLPERAG-----PAES----EP-DFFTTFAVRTLL-------GL
TTKLESV----TPKEEEA-VLKAFQP----------------------------------
-----------------------------------------------------LHI----
-----------------------DVNTQANNRYERND--NDGVDDS--ENQHCESCTSD-
-------QADPMSGSRAEPELEPEPAGQNEILLPHLRSVQ----------------TSLS
ESDNDAILVQGTLVHTTS-----------DTESDGESKDPDADETGTSKCGLNNA---AL
-----SA-VALDGNNQSKEESDSEGYGHSDDTVG--RDDTELHP--PISQW-LPRKLDS-
-ILEHDS-----SGKDRTLMDEQFSCLLATG-------ECSPELSGEDQ-RP--------
----SADNVSFHKAALTERSFQLPAFFSGLRVRKKGLNTEDGETITEIKPRENDLALLKL
RQPVKKSNITSGLTTK---KKSSEPKASPTFLEQLSHLLNIDVSKNDERTQDSGAGFGE-
---TEDSDEGPENKASGQTEPL----------FPS-EEIKSSPAESALDVFKALFTRPPK
KE-----TTADPSELE-----AIKRKMRNEKESLKAVFERSKSKP-GDGPS-DKSPDLSP
SEQDDKTPGRLQTVWPPPKANHEEVKVGLKYTEAEYQAAILHLKREHKEEIETLKSQFEL
RVFHIRGEHAVSTAQLEETIAHLKNELDNKLNRRNEEARDIGVSTEDDNP--PKTYRNVC
IQTDRETFI--KPSEEENRAVKNNQIVPKKLNISSLTHSIST-Q--GENKD-SYDVPSSE
SVLSCQP-KQMLPPPPPPPPPPPPPPPPFSDSSLPGLVPP--PPPLPTGPTSVTPHFAFG
PPL--PPQLSEGCRDFQAPAPPAPPP----------LPGLGPPV------P---------
-PPLPGSGLPPP-------------PPPLGPGLFFNSTLSSSQGPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSRPMKPLY
WTRIQLQGSRKTAIPTLW-ESLEEPDI---LDTTEFEYLFS-KDTTQEKRKPLSETYEKK
TKAKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAILCVDDSVVDLETLEALYENRAQK
DELEKIEQYYQTSKEEELKLLDKPEQFLYELSQIPNFTERAQCIIFQSVFSEGITSVHRK
VDIITRVSKALLNMTSVKEILGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDN
RINLVDYVVIYYLRHCDK------------------------------------EAGTDK
SIFPLPEPQDFFQASQVKFEDLIKDLRKLRRDLEA-------------------------
---SEKQMKLVCRESSEEHLQPFKEKLEEFFQKAK-EERKKEESSLENAQKCFEETVGYF
GIKPKPGEKEITPNYVFTVWYEFCSDFKTIWKRESKSISKERIKVAQQSVSKLTAEKKVE
TKKINPTASLKERLRQKEANVNAN-----------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDQILGITMGNQEGKLQ
ELSVSLAAED--DCFQSAGDWQGELPVGPLNKRS-----THGN-KKPRRSG-------GR
RESFGAL----PQKRTKR-KGRGGRE-SAPLMGKDQI---CSSHSLPLSRTRPNLWVLEE
RGNLLPNAALASSLQ-RRESCPPDIPKTPDTDLSFGSFETAFKDTGLG--REVLAPD--C
SSTEAG--------RDGVRR---PPSRL-----EHQQ--TGLSESHQDPEKHPEAE----
----KDEMEKPAKRTCKQKPVSKVVAKVQDLSSQVQRVVKTHSKGKET--------IAIC
PAAHAEFVPKADLLTLPG-----------AEAGAHGSRWQGKERQGDGSSQSPARETASI
SSVWASAEGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHT--SVPHT-R-PETRNK
RRAGLPL-----GGHKSLFLDLPHKV-----------GPDFSQPRGDKKKPSAPAPAALG
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQQHHRILRLPAQPGEREAALN
DSRGRNSRVFSGCVSADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGEPFEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELHLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAMVTARLEETIENLKHELEHRWRGGCEERKDVGISTDDDCP--PKTFRNVC
IQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GMASNQQ-KALP----PPPAPPLPA-----------SIPP--PPPLPPGLGSLSP----A
PLM--PP-VSAGPPPPPPPPPPPPPLP--------PHSSAGPPP-------PPPPPPLPN
SPAPPNSGGPPP------APPPPGLAPPPPPGLFFGLGSS-SQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCQESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
-------ME---DGDSSLNGSDGPRPELPTEDGIEITQSILSK-FSMKSFF-------GF
TSKLEST----KPGQEDA-MLKAFRNLG--------------------------------
----------------------------------LNLLQLESHNKDQ-EPKAQFSPV---
-------------LQNC-------------------------NDN-ANVETEPEGSG---
----------------------------------------KEQDGGVLLRQEPYPSSPPN
PSREDVLLVHGTLVHTTS---------------DSESEGEGLEEKEGANINS-------M
PDSSVLPEPSVVPKEAPGESRKNESMNEMDE----MELSGEVCS--VAPLE-SMSDLEP-
----------------------------REDSEFTELDP-RQDHPGEEDSSTIACTEDKN
SFAGNSENASSKKEASGEKSFQLPAFFSGLRVLKKGATTEGGETITEIKPKDSDLALLKL
TQPVQKSRALPGTLSRKSGEKTSDLKATPTLLEQISQLLNIDIPKAEQKEVCEQSR-EEE
M-------GSDTDRQCQTEEVP----------SQN-EGVKPKPPETALETFKAFFMRPPK
KG-----STADTSEL-----EAIKRKMRQEKESLRAVFERSNSRP-GDVSSDSKSADQSP
TEQDDRTPGRLQAVWPPPKTKDEEEKVGLKYTEAXXXXXXXXXXXXXXXXXXXXXAQFEL
KVFHIRGEHAVITAKLEETIENLKCELEQRLSGGCEKTRDACISTEDDYP--PKTFRNVY
IQTDRETFL--KPSEDESKTIKSNQIVPKKLTISSLSHISPL----NDNKDISSTLQSLE
SCSSGQQ-KSSL-----SPVPPLP-----------VVIPP--PPPLPPGLEAPPL-----
-----SSQPGAGPPPPPPPPPP------PPPPLPPLPLSSGNIL-------PPPPPPLPV
PPPLPTTGLVPPPP----PPAPPGIGPPPPP-PFFGGNTSFSQIPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISGGSQNTTPTLW-DSLEEPNI---QDPSEFEYLFS-KDTIQQKKKPLSESYEKK
NKVKKIIKLLDGKR-SQAVGILISSLHLEMKDIQQXXXXXXXXXXXXXXXXXXXXXRAQK
DELTKIRKHYETSKEEELKLLDKPEQFLYELAQIPNFAERAQCIIFRSVFSEGITSIHRK
VEIITRASKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXX
XXXXXXXXXXXXXXXXXXX----XXX----------------------------XXXXXX
XXXXXXXXXXXXXXXXXXXXXDLIDLIKLKTQLEA-------------------------
---SENQMVVVCKXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKNISKERLKVAQETVNKLTAEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHKPITELCYISFCLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED--DCFQSAGDWQGELPVGPLNKRS-----THGN-KKPRRSS-------GR
RESFGAL----PQKRTKR-KGRGGRE-SAPLMGKDKI---CSSHSLPLSRTRPNLWVLEE
KGNLLPNGALACSLQ-RRESCPPDIPKTPDTDLGFGSFETAFKDTGLG--REVLPPD--C
SSTEAG--------GDGIRR---PPSGL-----EHQQ--TGLSESHQDPEKHPEAE----
----KDEMEKPAKRTCKQKPVSKVVAKVQDLSSQVQRVVKTHSKGKET--------IAIR
PAAHAEFVPKADLLTLPG-----------AEAGAHGSRRQGKERQGDRSSQSPAGETASI
SSVSASAEGAVNKVPLKVIESEK--L---DEAPEGKRLGFPVHT--SVPHT-R-PETRNK
RRAGLPL-----GGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPSPPAPAALG
KVF----NNSASQSSTHKQTSPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPCRKSRVFSGCVSADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGETLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSL
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCP--PKTFRNVC
VQTDRETFL--KPCESESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GMASNQQ-KALP----PPP-----A-----------SIPP--PPPLPSGLGSLSP----A
PPM--PP-VSAGPPLPPP-PPPPPPLP--------PPSSAGPPP-------PPPPPPLPN
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVRYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
-----RNGIP--GCSGLVD----------LKNTAESEPDPLTT-FSVKTLF-------GF
STKFEST----APEEETV------------------------------------------
----------------------------------------------LK-AFQPLHSN---
INTQAH------------------------TWHERND--NGCNEDSE--NQHSVDSTSG-
-QA--------DPMSGGQAGLELDLADQNELLLQHLRFVQ--TSL-----------SDSD
NDDKDAILVQGTLVHTTS-----------DTESDTENKDLDTDENNASKY--------GL
KNAALCAEALDNSNQ-NKEESESEGDSNSVDPVDTD--DIELHP--PFSNQ-LPKELDGI
--LQYDS-----NGKDKMLMDEQFTHLLAT-------GECPQELSDEEQRPS--------
-----VDNIPLQKTALAEKTFQLPAFFSGLRVRKKGLTTEDGETVTEIKPRENDLALLKL
RQPVKKSSIASGLTIK---KKSSEPKANPTFLEQLSHLLNIEVSKNEDRTEDSGEGSGET
-EDS---DEAQENKASSKREPR----------FPS-EEIKSSPAESALDAFKALFTRPPK
KE-----TTADPSELE-----ALKRKMRNEKESLKAVFERSKSKP-GDGPS-DKSPDLSP
SEQDDKTPGRLQTVWPPPKANHEEVKVGLKYTEAEYQAAILHLKREHKEEIETLKSQFEL
RVFHIRGEHAVSTAQLEETIAHLKNELDNKLNRRNEKAKDIGVSTEDDNP--PKAYRNVC
IQTDRETFI--KPSEEENRAVKNNQIVPKKLNISSLTHSISA-Q--SESKD-NYNVQSSE
SVLSCQP-KQMLPPPPP-------PPPPLPDSSLSAVVPP--PPPLPMGPTSLASQFGSG
SPL--PPPLSEGCRNFQAPPPPPPP---------PL-PGQGPPV------P---------
-PPLPGSGLPP---P----------PPPPGPGFFFNSTLSSNQGPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPGRPMKPLY
WTRIQLQDNRKTAMPTLW-ESLEEPDI---LDTTEFEYLFS-KDTTQEKRKPLSETYEKK
TKAKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAILCVDDSVVDLETLEALYENRAQK
DELEKIKQYYQTSKEEELKLLDKPEQFLYELSQIPNFAERAQCIIFQSVFSEGITSVHRK
VDIVTRVSKALLSMKSVKEILGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDN
GINLVDYVVIYYLRHCDK------------------------------------EAGTDK
SIFPLPEPQDFFQASQVKFEDLIKDLRKLKRDLEA-------------------------
---SEKQMKLVCRESSEEHLQPFKEKLEEFFQKAK-EERKKEENSLESAQKCFEETVGYF
GIKPKPGEKEITPNYVFTVWYEFCSDFKTIWKRESKSISKERIKVAQQSVSKLTAEKKVE
TKKINPTASLKERLRQKEASVTAN-----------------

MEGTHCTLQLRKPITEVCYISFYLPRGEVRGFSYKGTVTLDRSNKGFHNCYQVREGSDVI
SLSLQPNEHPGDIFFKQTPTKDILTELYKLTAERERLLANLLSSDHILGITMGNQEGKLP
ELSVSLAPED--DYFQSAGDWPGEPPVGCLNKRS-----AHGN-RKPRRFG-------GR
RGSFEVL----PQKRTRR-KGRGSHQ-SAPQMGKDQI---CFSKSLPLSRTRPNLWLLNE
RGTSLPSGALTSSLQ-CRESCPPEIPRTLDASRGFGSFRKSSEDTGLG--RGGPPPD--F
SSTEPG--------DDG--A---GVPERGPHQLVHQQ--TGLSESHEDSKKHPEA-EKG-
--Q----REKSTEHTCRKKPISKVVAKVQDLSSQAQRVVRTHPEGEES--------VAIC
PAAQAEFIPRADWLTPPG-----------TKAGTHGSRWQGQEQQGDGSRPLSDR-----
KRTPASMEGAVNKVLLKVIESEK--L---NEATEGKRLGFPPNT--PATHT-L-PEARSK
RKAGLSP-----RDHKTSFLDLPHSG-----------GPDWSRPGGHEEKPAPPAPAALS
MLL----NNSSSQSSTHKQMAPVPSPLFPSFP-----SPEQHHRVLQLPPLPGEWEVAPD
DSLGRKKSTFSGSSSADTLEPPTSAKV------------------TETKGASSTSLRAGP
PRLV---PGDPLEESLDPG--K----------TAA-WPQYQSPPGISSEGFPRDCLSDQ-
-T-----TTKDLPNKDGG---AWFLGYRAGPACPFLLHEEREKPN-KSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVVTARLEETIETLKRETEHRWRGGREEMRDACISTGDDYP--PKTYRNVC
IQTDRETFL--RPCEGEGKTIRSNQIIPKKLNISSLSQLSPS----NDNKDTHVPLQSVE
GLSPSQQ-KAS----PPLPAPPLPAV---------IPPPP--PPPLPPGLGPLPP----V
PPP--PP-VSAGPPPPPPPP---------------LPPSAGPPL------P-PPPPPLPN
SSALPPSGGP----PP--APTPPGLAPPPPPGLFFGVGPSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDTAQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESITSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SIFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFKTIWKRESKTISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHNPITELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDIFFKQIPTKDILTELYKLTAERERLLASLLSSDHILGISMGIQEGK-Q
ELSVSLTPQD--DWFQSAGDWRGELPVGSLIKRR-----TQEN-KKPRRSG-------GR
RESSEEL----QKKRTRR-KGRGRQE-SVPQMGKDQI---CSSSSLPPSRARPNLRLLEE
RGNLVPQGTLTSSLR-RRESCPADILRTPDADLGFRFSRRTSQDTDLG---GLQPPNNRS
ISSEAG--------DAS--V---GGQPKSPGKLEPQQ--PGLSESLEGTEKHSEAERGG-
-TR----KSKSLERTCKKKPVSRVVAKVQELSAQVQRVVPTHPEGEGR--------IAFC
PEAQAEFIPKADLLTLPG-----------ARAETHSSRWLGEGQQGDKSLQPSATERTSI
SGSPASTEGAVNKVLRKVIESEK--L---DEATEGKRLGFSHST--AVTLT-F-PETRSQ
RKTQLPQ-----TGHKSLFLHLPHPV-----------GPVLSQPRDDERRASPPAPTALS
MVF----NNSSLQPSAHKRLSPVLSPLSPRFP-----SPQQHHRILRLPPLPGEGEAVLN
ECPGRKNGISSGFPSVDTLEPPSSAKV------------------TESKGASPTSLRAGQ
PWLV---PGEPSEKGLGPE--K----------ITA-QSQYQPPPGISSEGFPWDSFNE--
-Q-----TAKDFASRDGG---AWVLGYRAG---PFLHHEEREKRS-RSELFLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
KAFHIRGEHALTTARLEETIENLKQQLEHRWGGGCEEMRDACIATDDDCP--PKAYRNVC
IQTDRETFL--KPCEGESKTARSNQIVPKKLNISSLSQLSPS----KDSKDTHAQLQAGE
SISSSQQ-KTSPPPPIPPPPPP--------------AIPP--PPPLPPGLGPLPP----A
PPI--PP-VSAGPPPPPPPPPPPPPP--PPPPPPPLPPSAGPPP------P-PPPPPLPN
ALALPNSGGLP--------PPPPGLAPPPPPGLSFGLNSSSSLCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQIIDKSQNATPTLW-DSLEEPHI---QDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELIKIRKYYETSKE-ELKLLDKPEQFLHELAQIPNFAERSQCIIFRSVFSEGITSLHRK
VEIVTRASKALLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDS
GMNLVDYVVKYYLRYYDQSFS--------------LS------------FHILLSSGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLEDAQKSFETTVGYF
GMKPKTGEKEVTPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLDKTQGTNGMLTSLNPS---------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGAVTLDRSKKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED-D-CFQSAGDWQGELPVGPPNKRS-----THGN-KKPRRSG-------GR
RESAGAV----PQKRTKR-KGRGGRE-SAPLMGKDQS---CSSHSLPLSRTRPNLWVLEE
RGNLLPNGALASSLQ-RRESCPPDISKTPDTDLSLGSFETAFKDTGLG--REVLPPD--C
SSPEAG--------ADGARR---PPSGLEQ-----QQ--AGLSESHQDPEKRPEAE----
----KDEMEKPAKQTCKQIPVSKVVAKVQDLSSQVQRVVKAHSKGKAR--------IAIC
PAAHAEFVPKADLLTLPG-----------AEVGAHGSRRRGKERQGDGSSQSPARETASS
SSASACAQGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHR--SAPHA-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPCPPAPAALG
KVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFS----ADTLEPPSSTKV------------------TETKGASPAFLRAGH
PRLV---PGEPLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFNE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHADHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVVTARLEETIENLKHELEHRWRGGCEERRDVCISTNDDCP--SKTFRNVC
IQTDRQTFL--KPCEGESKTTRSNQLVPKKLTISSLSQLSPP----NDHKGIHAALQPME
GTASNQQ-KALP----LPTAPPLPA-----------PIPP--PPPLPLGLDSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLP--------LSSSAGTST----------------
--------------------TPTRLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETFEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEILTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAR-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------GGESAKAARDSLEAFKALSSGPPR
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSNSKP-ADGPSDSKSPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCP--PKTFRNVC
VQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPVE
GVASNQH-KAL----PPPPAPPLPA-----------SIPP--PPPLPPGLGSLSP----A
PPM--PP-VSAGPPPPPLPPPPPPPLPP--------PSSAGPP-------PPPPPPPLPN
SPAPPNSGGP----PP--APPPPGLAPPPPPGLFFGLGSSSSQCPP

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KTAIEHSCPMKPLY
WTILLIIDRSQNATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFAEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
-----MEDVG--DSLNGSDV----LEPDNAEAGLEMAQSILSK-FSMKSLF-------GF
TSKLEAV----DPEEDDA-VLKAFRRLD--------------------------------
------------------------------VAPTPGQDERSVAGSEQQEAEAEVP-----
------------------------------PDLGNDG--KT-------VETESEGSL---
-------------------------------GKAEAGTSIPGPELLPL--------STLS
VARDDVIWVRGTLVHTTS-----------D----SDSDDGGPEPDEGSSTQGPKSPSV--
-----LSEPPQETKEKPEDSRERIAT---REMD-----ATELCA--ETSRR-TPPEISGR
-------------------------QESGDGGLQPEHVPS--PDQDKEGSQVLPAVRDQN
LSVSVTENTSSKKEVPGEKSFQLPAFFSGLRVLKKGATAEGGETITEIKPKDGDLALLKL
TQPVQKSLGQAGPQTVRSGEKATDPKATPTLLEQLSQLLNIDMPRTELKAADPESPRKE-
-EMG---CGVDLESQGGPGEPQ----------TQA-GEVKPKPPETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMRNEKESLRAVFERSKSRP-ADGPPDSKSPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVVTARLEETIENLKRELEDRWR-GCEERRDACISTSDDCP--PKTYRNVC
IQTDRETFL--KPCEGESKTTRSNHIVPKKLNITSLSQLSPP----NESKDIHTSLQSVE
GTTSSQQ-KAS----PPPPAPPLPA-----------AIPP--PPPLPPGLGSLSP----A
PPA--PP-VSAGPPPPPPPPPPPLP-----------------PG------PPPPPPPLPN
SQAPLCPGGPP---P---APAPPGLAPPPPPGLYFGLSSSSSQGPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDPGEFEYFFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSEEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHQK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEV-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFQKAK-KEYKMEESHLENAQKSFETTVGYF
GMKPKSGEKDVTPSYVFMVWYEFCSDFKTIWKRESKNISKERLKRAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHNPIAELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDIFFKQTPTKNILTELYKLTAEKERLLDSLLRSDNILGVSMGSQEGKLQ
ELSVILATGD--EYFQSAGNWRRELPVSSLIRRS-----TQEN-KKPRRSG-------RR
RESPEEL----RQKRTRR-KGRGCQE-SAFQMGKDQV---CSSSSLSF-RARPNLRLLEE
RGNLVPRGTLTS-SLRRRESCPANILRTPDADLAFGNSGRTSEDTDLE---GPLSPD--S
SPTEVG-------------DADVGGQLKSSHQQEPPQ--PNVSES---HGKHAGAERWSS
RTR----KSKSLERTCSKKPVSKVVAKIQEPSAPVKRIVRAHHDGKGR--------VAYG
PETQTEFIPKADFLTLPG-----------GETETHSSGRLEEEQPGIKSLRSSAPERASI
TKEPASTEAAVNKVLRKVIESEK--L---DEATEGKRLGFSLNT--RATHT-F-PETRSQ
RKAGLPQ-----SGHKFLLLDLPHTV-----------GPDSPQPKCDEKKPTPQVPTALG
MVF----NNSSPQSSAHKRLSPVPSPLSPRCP-----SPQQHHRILLLPPLPSEGEVVFN
EYPSRKNDVSSGFPSADTLEPSSTTKV------------------TETKGASPTSLRASQ
TWLV---SEEASEKGLGPEKIT------------A-PPQHQLPPGIASEGFPCDNFKEQ-
-------TAKDLPNKDGG---VWVPGYRAGPPCPFLLHEEKEKTS-RSELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIETLQAQFEL
KTFHIRGEHALVTARLEEAIENLKQQLGKR-REGCEEMRDVCISTDDDCS--PKAFRNVC
IQTDRETFL--KPCDAESKATRSSQIVPKKLTIS-LTQLSPS----KDSKDIHAPFQTRE
GTSSSSQHKISPPAPPTPPPLPPPL----------IP--P--PPPLPPGLGPLPP----A
PP---IPPVCPVSPP----------PPPPPPPPTPVPPSDGPPPPP------PPPPPLPN
VLALPNSGGPPPPP----PPPPPGLAPPPPPGLSFGLSSSSSQYPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQINDKSQDAAPTLW-DSLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSEAYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFTVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQCKHHDQEASCRGKDLFSLYFHIAVHPQRKSGLELKQEAGTDK
SVFPLPEPQDFFLASQVKFEDLLKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPREYLQPFKDKLEEFFKKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKTGEKEVTPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVATN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPKTEGKAADPGSPKE--
-EMG---CGADQEIPGDPGEAH----------TQG-GEIKPKPPETALEAFKALFIRPPK
KG-----TTADTSELE-----AIKRKMRHEKESLRAVFERSKSRP-ADSPSDSKSPDQSP
TEQDDRTPGRLQAVWPPPKTKDAEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAMITAKLVHTIENLKQKLEHGWREDCEERKDXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X-XXXXXXXXXXXXXXX
XXXXXXX-XXXXX--XXXXXXXXXXX-------X-XXXXX--XXXXXXXXXXXXX----X
XXX--XX-XXXXXXXXXXXX---------------XXXXXXXXX------X------XXX
XXXXXXXXXXX---X----XX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX-XXXXXXXX---XXXXXXXXXXX-XXXXXXXXXX

PF02181 // ENSGT00870000136417_2_Domain_0 (1253, 1648)

XXXXXXXX
XXXXXIIKLLDGKR-SQTVGILISSLHLEMKDIQHAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VDIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMTVVCKESPKEYLQPFKDKLEEFFHKAK--EHKMES---HLAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKVAQASVSKLTSEKKVE
TKKINPTASL-------------------------------

MEGSHCTLQLRKPITELCYISFYLPRGEVRGFSYKGTVILDRSNKGFHNCYQVREGSNTF
SLSQQLNELPGDIFFKPSPTKDILTELYKLTAERERLLANLRSSDHILGISMGNQEGKLL
ELSVSVAPED--GCSQSAVDWWREPAVSPLNKRS-----TQGN-KKPRRFG-------GR
RESFEV------QKRIRR-KGRGGQE-STPQMGKDQI---PSSSCIPPFGAQLNLRLLEE
KGNLVPNGVLTSSLQ-RRESCPADIPSVPHADLGFANSGTASEDAGLG--RGALPTR--S
SSTEAG--------DKG--V---RDLPKRPHRLEQQQ--TDLPESQEGAKKHPEAQRG--
--G----LGKLTERTCRKKPISKVVAKVQDLSTQVQRVVNVPPEGEEK--------IVVH
PAVKTEFISTVDLLTLPG-----------PEAGASGSRWQRKEQQGTRSLQLPARESASV
SSLPASAEGAVNKVLLKVIESEK--L---DEATKGKRLDVPINA--RATHG-P-PETRSK
RRAGVPQ-----RGHKSLFLDLPYTT-----------GPGSSQCRGDERRPSPPVPAAPC
SGF-----NNSSQQPPHQQPPPAPSPICPRCP-----SPQEHHRILLLPPLPGEREAALN
AAPGRQSSILSESSSPDTLEPPSSAKV------------------TETKGASPASLRAGQ
PQLV---PGGTVERSLGPK--K----------TTA-PSQPLSSPGVSSEGFPGDRFSEQ-
-------TAKDF-PRDTG---AWVLGYRSGPPCPFLLPEDREKSN-RSKLYLDLNPDQSP
TEPDDRTPGRLQAVWPPPKTKDAEEKVGLKYTEAEHQAAILHLKREHKEEIETLQAQFEL
QAFHIRGEHAATTARLEETIENLKLELEQRLRGGREELRDACVCT-DDCP--PKAYRNVC
IQTDRESFL--KPCEGESKATRSNQIVPKKLNICSLSQLSPT----NDSKDIPAPLPSGE
GASPAHP-KTAPPPAPPPPPPPL-------------PIPP--PPPLPPGP----------
-PA--PA-PSAGSPPPLPL------------------GSAGAPS-------------SPL
LTPRPARGGGP---PP-----------------------------------AHLPMKPLY
WTRKNNSSPEY------L-S----HHL---RVC--LQFLCF-CDVLEKLFGSLSLYF---
-

PF02181 // ENSGT00870000136417_2_Domain_0 (1262, 1648)

SKFQIIKLLDGKR-SQAVGILISSLHLEMKDIQQAIFNVDDSVVDLETLEALYENRAQE
NELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFAEGVTSLHRK
VEIVTQASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQVGNGMMWE--TALMGFIQFYIILLPQR--FAPILTFEAGTDK
SIFPLPEPQDFFLASQVKFEDLIEDLRKLKKQLEA-------------------------
---SEKQMMVVCRESPKEYLQPFKNKLEEFFQKAK-KEHKMEESHLENAQKSFQTTVGYF
GMKPKAGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

MEGTHCTLQLHNPITELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDIFFKQTPTKDILTELYKLTAEREKLLDSLLRSDHILGISMGNQEGRLQ
ELPVSLVPEE--DCFQSAGNWSRELAVNSLIRRS-----TQGS-KKPRRSG-------RR
RESPEEL----RLKRTRR-KGRGRQE-SAPQMGKDQV---CSSSSLPPSRVRPNLQLLEE
RGNLVPQGTLTSSPRRRRESCPADILRTPDADLGFRSSGRTSEDTDLE---GPLSPD--S
SPTEVG--------DAG--I---GRQPKSPQEQEPP-------SLSESHEKHPGAERGG-
-TR----KSKSLERTCRKKPVSTVVAKVQELSAQVQRVVRAHPDGEER--------VAFC
SETHTEFIPKADLLILSG-----------AKDETQSSRSLGEEQQGVKSSQPSATERASI
PSEPASTEGAVNKVLRKVIESEK--L---DEATEGKRLGFSLNT--RAAHT-L-PETRSQ
RKAGLPK-----SGHKFLLLDLPHTV-----------GPDSPQPKCDERKPTPQTPTARG
MVF----NNSSPQSSAHKRLSPVPSPLSPRCP-----SPQQHHRILLLPPLPSEGEAAFN
ECPGRKNGLSSGFTSAVTLEPSSSTKV------------------TETKGGSPTSLRASQ
TWLV---SEEPSEKSLRPE--K----------ITA-LPQHQPPPGVTSEGFPCDSINE--
-Q-----TAKDLPNKDGG---AWVLGYRAGPSCPFLLHEEREKSS-RSELHLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
KTFHIRGEHALITARLEETIENLKQQLDHRWGGGCEEMRDACISTDDDCP--PKAFRNVC
IQTDRETFL--KPCEGESKTTRSNQIVPKKLNIS-LTQLSPT----KDSKDIHVPLQTGE
GISSSQQ-KISPPPP----TPPIPPP----------LIPP--PPPLPTGLGPLPP----A
PPI--SP-VSAGPPPPPPPPPPPPP----------LPPSAGPPP------P-PPPPPLPN
VLAPPNSGGLPPPPPPPLPPPPPGLAPPPPPGLSFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSQDATPTLW-DSLEEPHI---KDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSESVTSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYGLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQVGNEKMAS--GKQTG------------------VRKEAGTDK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPKEYLQPFKDKLEDFFQKAK-KEHKMEEIHLENAQKSFETTVGYF
GMKPKTGEKEITPSYVFMVWFEFCSDFKTIWKRESKSLSKERLKMAQASVSKLTSEKKVE
TKKINPTASLEIREKHIEYQLYNRGSGNIGYCSYLHEIQQA

MEGV----------------------------------------------GDSLNGSDEV
SEPEKPEAR---L-------------------EVAQSILSKFSMKTLFGFTSKLESAKPE
E-------ED--AVLKAFHSLVLDP-VPQLDDPS------HS--SHP-------------
Q---EAVA-----------------Q-VLPDLGNDGK---TAGAE---TESEGNQSIIED
AGI---------SLL-GQEP------------LPLSTLSMNRDDVILV--RGTLVNT--T
SDSDSD--------DGG--Q---QPEEGSNTSRPQSP--SVVAEPSQEPKEKPRDCGENS
ITGERDDAECCAEG-PRKTPSETS---------------SKPEPGDGG--------LQT-
------------------------------------EHSPVQGQAGEES----------S
QDQPAVT---DQTLIVGVTENAA--S--KKEVPGEKAFQLPAFF--SGLRV-L-KKGA-T
GEGGKTITEIKPKDGDLALLKLTQPVQKSLAQA----GPQTVKTGE--------------
-----------------KTADPKA---TPTLL-----E--QLSQLFILDMPKAE------
-------------------------------------------------------VRAGD
P-------EQPRKEEMGCGAAQESQSGPSGAQTQG-EEVKPKPPETALEAFKAIFVRPPK
KGTTADTSELEALK--------RKMKHEK-ESLRAVFERSRSRP--GDGPSDSKSPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAAVTARLEETIENLKHEIEHRWRGGCEEMRDACVSTDDDHP--PKTYRNVC
IQTDRETFL--KPCEGEGKTIRSNQIIPKKLNISSLSQLSPP----NDNKDVHVPLQSVE
GISPPQP-KASPP---------------PPAPPLPAAIPK--SSYVFTX-----------
-------------------------------------XXXXXXP-------PPPPPPLPN
SPALPNSGGPPP------APTPPGLAPPPPPGLFFGVGPSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1597)

KPAIEPSCPMKPLY
WTRIQISDKSQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSESITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SIFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMMVVCRESPKEYLQPFKDKLEEFFQKGR-ELHQLHIH---ESLKHLPF-PGPF
SEAH--G-----PSH-------PC------------------------------------
-----------------------------------------

MEGTHCTLQLHNPIAELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDIT
SLSQQPNEHPGDIFFKQTPTKNILTELYKLTAEKERLLDSLLRSDNILGVSMGSQEGKLQ
ELSVILATGD--DYFQSAGNWRRELPASSLIRRS-----TQEN-KKPRRSG-------RR
RESPEEL----RQKRTRR-KGRGCQE-SAFQMGKDQV---CSSGSLSF-RARPNLRLLEE
RGNLVPRGTLTS-SLRRRESCPANILRTPDADLAFGNSGRTSEDTDLE---GPLSPD--S
SPTEVG-------------DADVGGQLKSSHQQEPPQ--PKVSES---HGKQAGAERWSS
GTR----KSKSLERTCSKKPVSKVVAKIQEPSAPVKRIVRAHHDGKGR--------VAYG
PEIQTEFIPKADFLTLSG-----------GETETHSSGRLEEEQPGIKSLRSSAPERASI
TKEPASTEAAVNKVLRKVIESEK--L---DEATEGKRLGFSLNT--RATHT-F-PETRSQ
RKAGLPQ-----SVRKFLLLDLPHTV-----------GPDSPQPKCDEKKPTPQAPTALG
MVF----NNSSPQSSAHKRLSPVPSPLSPRCP-----SPQQHHRILPLPPLPSEGEVVFN
EYPSRKNGVSSGFPSADTLEPSSSTKV------------------TETKGASPTSLRASQ
TWLV---SEEASEKGLGPEKIT------------A-PPQHQLPPGIASEGFPCDNFKEQ-
-------TAKDLPNKDGG---VWVPGYRAGPPCPFLLHEEKEKTS-RSELYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIETLQAQFEL
KTFHIRGEHALVTARLEEAIENLKQQLEKR-RGGCEEMRDVCISTDDDCS--PKAFRNVC
IQTDRETFL--KPCDAESKATRSSQIVPKKLTIS-LTQLSPS----KDSKDIHAPLQTRE
GTSSSSQQKISPPAPPTPPPLPPPP----------IP--P--PPPLPPGLGPLPP----A
PP---IPPVCPGSPP----------PPPPPPPPTPVPPSDGPPPPPPPPPPPPPPPPLPN
VPALPNSGGPPPPPP---PPPPLGLAPPPPPGLSFGLSSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQINDKSKDAAPTLW-DSLEEPHI---RDTSEFEYLFS-KDTTQQKKKPLSEAYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFTVDDSVVDLETLAALYENRAQE
DELTKIRKYYETSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GMNLVDYVVKYYLRYYDQ------------------------------------EAGTDK
SVFPLPEPQDFFLASQVKFEDLLKDLRKLKRQLEA-------------------------
---SEQQMKLVCKESPREYLQPFKDKLEEFFKKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKTGEKEVTPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVATN-----------------

MEGTHCTLLLRKPITELCYISFYLPKGEVRGFSYKGTVILDRFNKGFHNCYQVREESDTI
SLSQQLSELPGDIFFKPTPTKDILTELYKLTAERERLLADLRSSDHILGISMGNQEGKLL
ELSVSLAPED--DCSQRAGDWWGELPVGPLNKRS-----THGN-KKPQRSG-------GR
RESFEV------PKRRRR-KGHGSQE-STPLMGKDQI---CSSSCHPP-RAPLNLQLLEQ
RGNLVPNGVLTSSRQ-RREGCPEDIPGTPDADLGFANFTMASEDAGLG--RGVRPLD--S
CATEAG--------DDG--V---QEMPRRTHRLEREQ--TGLPESQEGAKKHPKAQRGG-
-------LGKLAEQTSGKKPISKVVAKVQDLSTPVQRVVNVHPEGEEK--------TAAY
PEVKAEFVSNVDLLTLPG-----------AEAGADGSRWQSKEQQGTKSLQLPARERASM
SGLPASADGAVNKVLLKVIESEK--L---AESTKGKRLGVLN-T--GATRS-L-QEPRSK
RRTGVPQ-----RGHKSLFLDLPCTI-----------GPDSSECRGDERTLSSPVPAAPS
MGF----NNSSSQSSTHQQQSLALLPLSPRHS-----SPEQHHRILQFPPLSSEREAALN
DFPSRQNSIFSASPSAETLEPSSSAKV------------------TETKGANPASLGADQ
PQLV---PGENLEKSLGPG--K----------TTA-EPQQPSPPGVSCEGFPWDRFSE--
-Q-----TAKDLPSRDAG---AWVLGYRAGPPCPFLLHEDREKSS-RSKLYLDLNPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIESLQAQFEL
QVFHIRGEHAASTARLEETIENLKLELEHRWRGGCEDLRDACVSTDDDCP--PKAYRNVC
IQTDRETFL--KPCEGDSKTTRSNQIVPKKLNISSLSQLSPP----SDNKDTHTLLQNGE
AMSPSPP-XXX-------XXXXXXXX---------XXXXX--XPPLPPGPGPLQP----V
SPP--PT-LSCRPPPPPPPPPP------------PLPPSAGPPP------P-PPPPPLPV
SQAVP---------PP--APSLQGLAPPPPPGLFFGLSSSSSQAPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1535)

KPAIEPSCPMKPLY
WTRIQISDS-ENAAPTLW-DSLEEPDI---QDTSEFEYLFS-KVTAPQKKKPLSETYAEK
NKVKKIIKLLDGKR-SQAVGILISSLHLEMKDIQQAIFNVDDSVVDLETLEALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGVTSLHRK
VEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIGDLRKLKKQLE

ENSGT00870000136417_2_Linker_0_1 (1535, 1573)

AHTHSKLCCVHSGCCTGAYGSCTGQL
SPASERQMMVVC

PF02181 // ENSGT00870000136417_2_Domain_1 (1573, 1648)

KESPKEYLQPFKDKLEEFFQKAK-KEHKMEESYLENAQMSFQTTVGYF
GMKPKAGEKEITPSYVFMVWYEFCSDFKAIWKQESKNISKERLKTAQASVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTS-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------XS----EP-DVFTTFAVRALF-------GL
TAKLESV----TPKEEEA-VLKAFQP----------------------------------
-----------------------------------------------------LHT----
-----------------------SVNTQAKNRYERND--NDSVDDS--ENQHGAGCTSD-
-------QADPVSGSCA--ELEPEPAGQNEILLPHLRSVQ----------------TSLS
ESDNDAILVQGTLVHTTS-----------DTESDGESKYPDADETSTSKCGQNNA---AL
-----FS-VTLDSNNQSEEESNSEGYRHSNDTVG--RDDTELYP--PISQW-LPSELDS-
-VLECDS-----SGKDRTFMDEQFSSLLATG-------ECPPEIPGEDQRRP--------
----SVDNVSLHKAALAEKSFQLPAFFSGLRVRKKGLNTDDGETITEIKPRENDLALLKL
RQPVKKSNITSGLTTK---KKSSEPKASPTFLEQLSQLLNIDVSKNDERTQDSGAGFGE-
---IEDSDEGPENKASGKTEPL----------FPS-EEIKSSPAESALDVFKALFTRPPK
KE-----TTADPSELE-----AIKRKMRNEKESLKAVFERSKSKP-GDGPS-DKSPDLSP
SEQDDKTPGRLQTVWPPPKANHEEVKVGLKYTEAEYQAAILHLKREHKEEIETLKSQFEL
RVFHIRGEHAVSTAQLEETIAHLKNELDNKLHRRNEEARDIGVSTEDDNP--PKTYRNVC
IQTDRETFI--KPSEEENRAVKNNQIVPKKLNISSLTHSIST-Q--GENKD-SYDVPSSE
SVLSCQP-KQMLPPPPPPPPPPPPPPPPFTDSSLKGLVPP--PPPLPMGPTSVTPHFASG
PSL--PPQLSEGCRDFQAPSPPAPPP----------LPGLGPPI------P---------
-PPLPGSGLPPP-------------P-PPGPGLFFNSTLSSSQGPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSRPMKPLY
WTRIQLQGSSSITEVKYLKVALLFPVYLRTYEELTLLYFFK-KQDSWIFAMPLCLLVRKK
NEGWRIIKLLDGKR-SQTVGILISSLHLEMKDIQQAILCVDDSVVDLETLEALYENRAQK
DELEKIKQYYQTSKEEELKLLDKPEQFLYELSQIPNFTERAQCIIFQSVFSEGITSVHRK
VDIVTRVCKALLNMTSVKEILGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDN
RINLVDYVVIYYLRHCDK------------------------------------EAGTDK
SIFPLPEPQDFFQASQVKFEDLIKDLRKLKKDLEA-------------------------
---SEKQMKLVCRESSEEHLQPFKEKLEEFFQKAK-EEHKKEESSLENAQKCFEETVGYF
GIKPKPGEKEITPNYVFTVWYEFCSDFKTIWKRESKSISKERIKVAQQSVSKLTAEKKVE
TKKINPTASLKERLRQKEANVNAN-----------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQ
ELSVSLAPED--DCFQGAGDWQGELPVGPLNKRS-----THGN-KKPRRSG-------GK
RESFGAL----PQKRTKR-KGRGGRE-SAPLMGKDKI---CSSHSLPLSRTRPNLWVLEE
KGNLLPNGALASSLQ-RRESCPPDIPKTPDTDLGFGSFETAFKDTGLG--REVLLPD--C
SSTEAG--------GDGIRR---PPSGL-----EHQQ--TGLSESHQDPEKHPEAE----
----KDEMEKPAKRTCKQKPVSKVVAKVQDLSSQVQRVVKTHSKGKET--------IAIR
PAAHAEFVPKADLLTLPG-----------AEAGAHGSRRQGKERQGDGSSQSPAGETASV
SSVSASAEGAVNKVLLKVIESEK--L---DEAPEGKRLGFPVHT--SVPHT-R-PETRNK
RRAGLPL-----GGHKSLFLDLPHKV-----------GPDSSQPRGDKKKPSPPAPAALG
RVF----NNSASQSSTHKRTSPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFSGCVSADTLEPPSSAKV------------------TETKGASPAFLRAGQ
PRLV---PGETLEKSLGPGKT------------TA-EPQHQSPPGISSEGFPWDGFSE--
-Q-----TPKDLPNRDGG---AWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKDVCLSTDDDCP--PKTFRNVC
IQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GMASNQQ-KALP----PPPAPPLPA-----------SIPP--PPPLPPGLGSLSP----A
PPM--PP-LSAGPPPPPPPPPPPPPLP--------PPSSAGPPP-------PPXXXXLPN
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDPSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRQYYKTSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPRTELKAANPESSRGE-
-EMG---CGGDQESQNGPGGTQ----------TQG-SEVKLKPPETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMRHEKESLRAVFERSKSRP-TDGPCEPKSPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
QAFHIRGEHAVITARLEETIDNLKHELEHRWRGGCEEMRDACISTDDGCP--PKTYRNVY
IQTDRETFL--KPCENENXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXX
XXXXXXX-XXXX---XXX-XXXXXXX---------XXXXX--XXXXXXXXXXXXX----X
XXX--XX-XXXXXXXXXXXX---------------XXXXXXXXX------X-XXXXXXXX
XXXXXXXXXX----X---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX

PF02181 // ENSGT00870000136417_2_Domain_0 (1205, 1648)

XXXXXXQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQXXXXXXXXXXXXXXXXXXXXXRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLQMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQXXXXXXXX--XXXXXXX-------------------------
---------XXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKMIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKRINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------GGETITEIKPKDGDLALLRL
TQPVQRSLAQAGPQTVKTGEKTDDPKATPTLLEQLSQLLSIDVPKAEPKAEDPEQPSGE-
-DMG---CSAPQESESSPGGAP----------SQG-GEVKPKPQETALEAFKALFIRPPK
KG-----TTADTSELE-----ALKRKMKHEKESLRAVFERSKPRL-ADGPSDSKSXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYHAAILQLKREHKEEIENLQAQFEL
QAFHIRGEHAVTTARLEETIENLKYEIEHRWRGGCEEMRDECISTDDDCP--PKSYRNVC
IQTDRETFL--KPSEGEGKTARS

PF02181 // ENSGT00870000136417_2_Domain_0 (984, 1648)

NQIIPKKLNIPSLSQLSPP----NDNRDTHGPLQ---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------QNSAPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSDTYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQXXXXXXXXXXXXXXXXXXXXXRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITALHRK
VEIITQASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLKKLKRQLEA-------------------------
---SEKQMAVVCKESPKEYLQPFKDRLEEFFQKAK-KEHKMEESHLETAQKSFETTVGYF
GMKPKSGEKEITPNHVFMVWYEFCSDFNTIWKRESKNISKEXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXKERLRQKEASVSSS-----------------

MEGTHCTLQLHKPITELCYVSFCLPSGEVRGFSYKGTVTLDKSNKGFHNCYQVREGSDII
SLSQWPNEHPGDIFFKRTPTKDILTELYNLTAERERLLASLLSSDHVLGIAMGNQEGKLP
ELSVSLAPED--DCFQGAGDWQGEPPVGSLNKRS-----THGN-KKPRRFG-------GR
RESFQTL----PQKRIRR-KGHGGPK-SAAQLGKDHI---YSSNSFPPFQARPG--LLEE
RGNLVPNGAHTTSLQ-RRESCPPEIPRTLDADPGFGSFGVASEDTGPG--RGVLPPD--H
SFPEAG--------VDG--V---QGPQRRPQRLEHQQ--TGLSENHKDPEKHPEA-ESG-
--W----REKSAEQTCRKKPVSKVVAKVQNLSFRVQRVVQTHAEDEER--------IALG
SEPQAEFVSKANLLTLPG-----------AEAGAQYSRLWSREQQGDQL---SATLRVST
SSTSASAEGAVNKVLLKVIESEK--L---DEASEGKRLGFLLST--KATHT-L-PETRSK
RKMGLPL-----SGHKTFVLNLPHSV-----------SHDASQPRGDEERLTSAVLATFG
MVFNNL--SPQPQSGTHRRKPPVSSPLSPRLP-----SPQQHHRILRLPSLPGEREAALN
DSPARKRGAISGSPSADTLEPPSSAKV------------------TEPKGASSASLRAGE
LRLV---PGEPLEKSLGPG--K----------TTD-RLQHQSPPGISSEGFSRDCSKE--
-Q-----TTKDLPNRDGG---SWVLGYRSGRAHPFLHHEEKEKPN-KSELYLNLHPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKQEIENLQTQFEL
KAFHIRGEHAAVTARLEETIENLKHELEHRWRGGCGEMRDACISTDEDSL--PKTYRNVC
VQTDRETFL--KPCEGESKTTKSNQIIPKKLNISSLSQLSPT----SDNKDIHAPLQSVE
SISSNQQ-KAS----PPPPAPPLPA-----------PIPP--PPPLPPGLGPLPP----A
PPT--PP-VSAGLPPPPPPPPPLPP-----------TPSAGPPP------P-PPPPPLPN
LPPLPNSGGP----PP--APTPPGLVPPPPPGLFFGVGSPSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDTSEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQAVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITGASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRNT
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SIFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMMVVCKESPKEYLQPFKDKLEDFFQKAK-KEHKMEEGHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFTVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MPKAEPKAEDPAAFSGEA
MGCS----STDQESQSGPREAQ----------TQGLGEPKSKPTETALEAFKALFIRPPR
KG-----TTADTSELE-----ALKRKMRHEKESLKAVFERSKSRP-AEGPSDSKSPDQSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAATTARLEETIEHLKHDLEHRWRGGCDEMRDVCISTDDDSP--PKTYRNVC
IQTDRETFL--KPCEGESRTTRSSHTVPKKLNISSLSQLSPP----RDCKDGHASLLPLE
SSSSHQQ-KTSP----PTPAPPLPA-----------LIPP--PPPLPSGLESWPP-----
-VP--PTPLSTGPPPPPPPPPSIGPP----PPPPPPPPSIGPPP-------PPPPPPLPN
IPPPPSSGGPP-------PPTPPGLAPPPPPGLFFGTGSPSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDKSPNAAPTLW-DSLEEPDI---RDPNEFEYLFS-KDTTQQKKKPLSEAYEKK
NKVKKXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERXXXXXFRSVFSESVTSLHRK
VDILTRASKGLLHMKSVKDILALILAFGNYMNAGNRTRGQADGYSLEILPKLKDVKSRDT
GINLVDYVVKYYLRYYDQ------------------------------------EAATEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMTVVCKESPKEYLQPFKDKLEEFFQKXX-XXXXXXXXXXXXXXXXFETTVGYF
GMKPKSGEKEITPNYVFMVWYEFCSDFQTIWKRESKNISKERLKTAQESVNKLTSEKKVE
TKKINPTASLKERLRQRGTSVTTN-----------------

MEGTHCTLQLHKPITELCYISFYLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDII
SLSQEPDEHPGDIFFKQTPTKDILIELYKLTTERERLLADLLSSDHILGIRMGNQEGKLP
ELSVSLAPED--DCFQSAGNWQGELPVGPLNKRS-----THGN-KKPRRFG-------GR
RESFGAL----PQKRTRR-KGRGARE-SAPLMGKDQM---CSSNSLPLSKTRPNHWLQEE
RGNLLPNGALDSSLQ-RRESCPPDIPKTPGTDLGFGSFETAFKDTGLG--REVLPPD--C
SSTEAG--------EDG--F------RRLPSGLEHPQ--TGLSESHKDPEKYPEA-EKD-
--E----MQKPAKRTCKQKPVSKVVAKVQDLSSQVQRVVKTHSKGKEK--------IAIF
PEAQAEFVPKADLLTLPG-----------AEAGARGSRRWGKERQGNGSSKSPAREAASI
SSAPASAEGAVNKVLLKVIESEK--L---DEAPEGKRLGFPFHT--SVPHT-R-PETRNK
RRAGLPL-----SGHKSLFLDLPHKV-----------GPDSSQLRGDDKKPSPRAPAALG
TVF----NNSSSQSSTHKQTLPVPSPLSPRLP-----SPQQHHRILRLPALPGEREAALN
DSPGRKSRVFPGCVSADTLEPPSSAKV------------------TETKGASSAFLRAGQ
PRLV---PGEILEKSSGPG--K----------TTA-EPQHQSPPGISSESFPWDGFNE--
-Q-----TLKDLPNRDGG---TWVLGYRAGPACPFLLHEEREKSN-RSELYLDLHPDHSP
TEQDDRTPGRLQAVWPPPKTKDTEEKVGLRYTEAEYQAAILHLKREHKEEIENLQAQFEL
RTFHIRGEHAVITARLEETIENLKHELEHRWQGGCEERKDACISTDDDCP--PKTYRNVC
IQTDRQTFL--KPSEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDIHAALQPME
GAQSNQQ-KAP----PPPPAPPLPA-----------SIPP--PPPLPQGLGSLSP----A
PPM--PP-VSAGPPPPPPPPPPPPPLPPP--------SSVGPPP-------PPPPPPLPN
FPVPPNPGGP----PP--APTPPGLAPPPPPGLFFGLGSSSSQSPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNAAPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSETYEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLEALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSIFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAK-KEHKMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVNTN-----------------

------------------------------------------------------------
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-----------------------------------YHAAILHLKREHKEEIENLQAQFEL
RAFHIRGEHAVITARLEETIENLKHELEHRWRGGCEERRDVCISTNDDCP--PKTFRNVC
IQTDRETFL--KPCEGESKTTRSNQLVPKKLNISSLSQLSPP----NDHKDTHAALQPME
GMASNQQ-KALP----PPPAPPLPT-----------SILP--PPLLPLGLGSLSP----A
PPV--PP-VSAGPPPPPPPPPPPPPLP--------LSSSAGPPPPPP---P----PPPPY
SPAPPNPGGPPP------APPPPGLAPPPPPGLFFGLGSSSSQCPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KPAIEPSCPMKPLY
WTRIQISDRSQNATPTLW-DSLEEPDI---RDPGEFEYLFS-KDTTQQKKKPLSESFEKK
NKVKKIIKLLDGKR-SQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQE
DELVKIRKYYETSKEEELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRK
VEIITRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDN
GINLVDYVVKYYLRYYDQ------------------------------------EAGTEK
SVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEA-------------------------
---SEKQMVVVCKESPKEYLQPFKDKLEEFFQKAR-KEHNMEESHLENAQKSFETTVGYF
GMKPKSGEKEITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVE
TKKINPTASLKERLRQKEASVTTN-----------------

--------------MELCYVSFFLPRGNVRGFTYKRCVTRDKARTCFDNCYRISEERETA
AHKDPPYERFTED-LKEATTQNILTELYKLTAAKDRLLVQLLEASHKLGSIMGNQDGKFQ
DLPDGYKFPE--DEAHGHVDFHESFS-ASVEKKV-----PSTKVKKNRRLS-------RR
KESIEDFVNKKIKWKSST-------EASATQVRDKTSSAKVSLTGSTDSLSRPKLQSVEN
KDSYLPGPMVKNAQGKHSES-----SGMLGSESAMGSLLSVYDNDVFA------------
---------DFSLLPHSDSL---LKELQSAIDIMPEQPSTQVLEGY-IFEKHCT------
-------EHESNEQASSGRSIKTVTAKLQDISTCVQKVVHTYNYQEDGAEERRCENITEL
IDEQKEFVSQIDVPMMYEPL--QCHIEKQLYGGVYNDRH-GRL------------ETCNN
NIEPLPSCEYVNKNLLRVVKSES--M---DETEYWL--GQMDRRGEKCSYGLKLPEKLSK
SQESLNH------------VTVPHSA----------------HIKLQDKPTAV-----KT
PTFDT-ASIMHIPCTMCKGISPVSSPVSTHLS-----SPQPHHLILPLQTQHVEEDLKLC
GVEH--WS-----ALPDIFREPSSLQE-----------LGYDFKGSTTFNMDPDNYLFDD
--F--------LQNVKGK--------------KTTLQPNLPPP-G-GGEALKDVSRGPD-
-------T---SSGLQAGVSEEL------SSVCDNKTTVGRPDH-SILHLSLEIHTDLSP
SDGEDRTPGRLQAVWPPPKPKDEEEKVGLKYTEAEYQAAILHLKREHKDELETLKSQSEV
AIFNVRGEQAVQTAKLEEEIQKLQADLQNKLSHQNGEKRDVCVSTEDENS--PKSFRNVC
IQTDRETFL--KPNEE-DKSQKNDTVLPKKLNIASISQNLASPISPSDNSQHNFPLASLS
V--------TTP------PPHPLSTS----------SQTASSPTPLDCDLSSVPP-----
-----PP-------------P--------------F-PGGGPP---------PPPPP---
---FPGYGSSAVPPP----------LPLPLPGLFFGLS-----KPR

PF02181 // ENSGT00870000136417_2_Domain_0 (1187, 1648)

KAPVEPGCPMKPLY
WTRIQLKNGSTSSSNTLW-ENLKEPNI---ADTKEFEDLFA-KATVQQKKKPLSDSYEKR
AKAKQVIKLLDGKR-SQAVGILISSLHLDMKDIQQAILNVDNSVVDIETLEALYENRAQK
EEMEIIKKHYQTSKAEDVKLLDKPEQFLYELSQIPNFVERSQCIIFQSVFLEGISSVRRK
VDIISRACDCLLERVSVRDIIGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDN
KASLVDYVVRYYLRYFDQ------------------------------------DAGTDK
SVFPLPESQDLLLASQVKFEDLDKDLRKLKKDIEV-------------------------
---CEKQLKAVVKDSPKENIQPFKDKMSSFLNKAAKEEYKTEESKLTRSQNRFEETIGYF
GCKPKGNDKEITPNSFFVLWYEFCGDFKSVWKRESKVLSTERLRQAQESVNKLTAEKKVE
TRKINPAASLKEKLRQKEASVSTN-----------------