Query Results 

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQ
ETLQVMEAPPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREGPHLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAPQPMLVKECEL

PF04130 // ENSGT00850000132278_2_Domain_0 (375, 2024)

VKDVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKLYWTH
GYVLISKEVEDCVPVFLKHIAHDIYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
V-SEAHQPQE--PPDVLLS-VHPQVTSP----GPEH---------PEGGQGCDSGS---A
-EQHSAAWDGRNRPGLLTPQPLKPL-----AV-GAGGT-GLQQAEEARPFSDSLSIGDFL
PVGPG------------------AEPSMQTGMVPLLEVALQTINLDLPPSA---PGEAPA
VASTQPSRPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDSCGKLD-ACGST
L---RET---------LPPSYPPRRAALEEGSSQPTEQLCGQES----------GGGLPT
GYYASKIAPTRPRW-NTHGHV---SDASIRV--------------GENMSDVAPTRPRWN
THGHVSDASISLGESVSDVAPTRPRWN---IHGHVSNASI-RVGENVSDVAPTRPRWNIH
GHVSDTSIRFGENVSDVAPTRSRWNIHGHVSNA---------------------------
------------------------------------------------------------
----------------------SISLGEPVSDVAPTRPRWNTHAPIPPPHVMLGELSPEA
EPNT-----PRPQQSPAGHTSQSALS----------------------LGAQSTVLDCGP
----RLPVEVG-----PSLSSPSLGCGEESI-----------------------------
---------SVGENVSDVAPTQPS------WPNT---PGD----SVSEELGPGRSGDTE-
----------DLSPSWPL---------NSQEDTAAHSSPGPGEEEEE-----AGAAEAQG
REQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDTQVQ---SATDET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTAHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITEGCLSKYSGVFSFLLQLKLMMWALKDVCFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASVPQLFDDLCEALLPAAK--ARLGQRGVSRKRAKQGLKRVAYNALFTNLFQEETHKLQ
ADLSKLPVKNKVLLLSFDLRAGGLGPEADRLEELVEELQAAP--GCPLTEVASVLDLLVR
LAGSGPPQVLQRKRDYFFNNKHVGRNVPYSGYDCYDLSVFEMDVQSLISREEYLCQDMVR
KALQVMEAAPGTGLPTV--GLFSYGDPCSDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
MPDSADLSGL------AIKVPQSVDQSEDEGFQSASNLTPDSQSEPGMTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHKEEPYLTEAGRDTFDR-FCRLRQGELQVL-GGGL
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 1936)

DALNVL-IGVVSTTFSLCQPAQTFMVRRGVHVSGASPESISSLL
SEVAECGTHYARLSQFSLQPLLDSSCSKGLVLQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVG-------GGGP-----RAEFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLQTSCEPYTRFIHDWVYSGLFRDTYGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSP
EELKEVERDCAIY-VGRMERVARHSSISKEEKELRMEIAKQELIVQAREAASRVLRALSD
RQTSERMALDARKREQFQRLKEQFVRDQERRRAARQEDPDGDFGYARELRDRERRLRALE
EQLERKARQALVDHYSKLSAEAARREQKALWKIQRHRLAGARLR-FLVEDERRTREMLKD
V-CEKSSE----APAVLPG-ARSQASSP----GPEH---------LAGGSTCDSGY----
AGRHVAAYDCPSAQTPRLPRPLV---AAVC-------GPQPERVGRPGPFSEGLGIQDFL
PTARE------------------AGEAEHAGVAPILEQALQTIGSDLPPSA---VSEV--
-AGTEPSGPQEYDFRTILRPAVVTLASPASLQTVGGGSSNEGQQLWGDSLMQLENTCVPD
GPM------------AVPHSHPPRLRSSQEGSSQAMGQLLGHVP----------GGSIPA
---------------------------------------------GGYASGMAPSRPQWN
VHGHVSDASIKVGENVCDVAPSRPRWN---VHGHVSDASI-KVGENVCDVAPSRPRWNVH
GHVSDASIKVGENVCDVAPSRPRWNVHGHVSDASIK-----------------------V
GENVCDVAPSRPRWNVHGHVSDASIKVGENVCDVAPAR-----PRWNVHGHVSQSRVVLG
ALSGEDQPDTPAPY----------------------------------------------
-------------QSPTDHESQSGLS----------------------LGAQSPVGGHEP
----RRPADRASDGSCSHVVSSGSGEASD----------------------------QAS
LSAVAASG--AL-------------------GDSI-------------PEEPGRSGDTE-
----------DLSPSHPS---------SSQEGVATGSSPGLGEEEA--------AAQRWG
QEQAYLTGLAEQYRLEQYPDSYEAMSEPPVAHLLHHGLPRAFSLPEEPRVR---SDADET
AVELSELLPLPVLMKHSITAPLAAHVSLVNKAAVDYYFVELGLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQYSLHGDTPYAANLSFALKFLPEA
FAPNAPDVLNCLELRYKVD-WPLNIVVTESCLSRYSGIFSFLLQLKLMMWTLKDICFHLK
RAG----EARPDRLSP-------------------QGT------VSHWLP----------
---------PPKAACLP--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQPWVPAGGPRGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

MASVPQLLDDLCEALLPAAD--AQPGPRRGGRPRAKRSLKRAAYDALFSHLFREETRRAR
PGLPRLPVKNRVLMLSFDLRVAGLGAEADRLERLLAELEAAP--SGRLAEAGPVLELLVR
LAGSGPPRALRRPRDYFLHSQHVGRNVPYGGYDCSDLSAFEMAVRSLICGEECLCQDAVR
GALQVMEAAPGAGLPAAGSGLFSYGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADVSGL------PIKVPQSVDQSDDEGFQSASNLTPDSQSEPGVTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDTFDR-FCRLCRGELQAL-GGGL
LQVPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_1 (377, 722)

DVLNVL-IGVVSTTFSLCQPAQTFVVKRGVHVSGASPESISSLL
SEVAECGTHYARLSQFSLQPVLDSSCGKGLVFQAFTSGLRKYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPG-AGGEP-----RAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYICGK-TINLLKLCCPRHYLYWSDVPVPRISVIFSP
EELKEVERDCAIY-VGRMERVARHSSISKEEKELRMEIAKQELIVHAREAASRVLRALSD
R

ENSGT00850000132278_2_Linker_1_2 (722, 1790)

QTSERVALDARKREQFQRLKEQFVKDQERRRAARQEALDDDFGHARELRDRERRLRALE
EQLERKARQALVDHYSKLSAEAALREQKALWRIQRHRLASTRLR-FLVEDQKRVQEMLKD
V-SEGKPLE---PLAVIPS-VGSQALSP----GLAH---------PAGGGRSDSGYV---
VQQRVAEWDSP---SAQTPQLLKPLAAGTHGS---------GPGADPGPFPEGLSIQDFL
PTAGE------------------AEQPVPTGVASVLEEALQTIGSDLPPSA---PSEV--
-VGTEPPGAQEYDFRTILRPAVVPLASPGSVQTVGGGLNDKGPQLWGDSVLSPENTGVPD
RQV------------ALPHPHPPGHKSPQEERSQAIGQVLGHVS----------EGSIPA
---------------------------------------------GGYVSGMAPSRPRWN
IHGHVSDASIKVGENVWDVVSSRPRWN---IHGHVSDASI-KVGENVWDVAPSRPRWNVH
GHVSDASIKVGEN-----------------------------------------------
---VWDVASSRPRWNVHGHVSDASIKVGENVWDVAPSR-----PRWNIHGHVSESHVVLG
ALSGEGQPNAARPC----------------------------------------------
-------------ESPPDHVSQSGLS----------------------LGAQSPVWEHEP
----QLPAETASDGACAQVAGSGSGHARGLQAPLSAVVGSGDLGDGNPE--EPGEWDPTA
VLSVVAP----------------------------------------VGPRSGTSADTD-
----------SLSPGHPI---------SLQEGAAAPSSPSLGEEE--------AAAQRWG
QEQAYLTGLAEQYRLEQYPDSYEAMSEPPVAHLLHHGLPRAFALPEHPRGR---SGADET
AVQLSELLPLPVLMKHSITAPLARQLSA-----------------PALL

PF04130 // ENSGT00850000132278_2_Domain_2 (1790, 2024)

QRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQYSLHGDTPYAANLSFALKFLPEA
FAPNAPDVLSCLELRYKVD-WPLNIVVTEGCLSRYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSQAAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVTWCEFRARLAQVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQPWVPASGPRGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------IAGR------HLGL-R
IPAVVVWPSL------CLQVPPNVDQWEDEGFQSASNLTPDSQSEPSMTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAAQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_1 (377, 844)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELEDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLH-FLLEDEKHVQEMLKA
M-S

ENSGT00850000132278_2_Linker_1_2 (844, 1737)

EAHQPQE--PPDV-LS-VHPQVTSL----GPEH---------QEGDQGCDAGP---A
-EQHSAACDGRNRPGLLTPQSLKPL-----AM-GAGGT-GLQQAEEAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAAAASPAPGPLKAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRATPKEGSSQPTEQLFGHES----------GGGLPT
GGCASEIALTRPQW-NIHRHV---SDASIRV--------------GENVSQVAPARPRWN
THGHVSDASISLGESVSEVAPTRPRWN---IHGHVSDASI-S------------------
------------------------------------------------------------
----------------------------------------------------------LG
EPVSDVVSTRPRWNAHGHVSDASISLGEPVSDVVSTRPRWNTRASVPPPHMMLGAVSPEA
GPNTPGPHTPGPQQSPPGHTSQSVLS----------------------PGAQSTVLDCGP
----RLPVELG-----PSLSSPSSGCGEGSI-----------------------------
---------SIGENVSDVAPTWPW------LPNT---PGD----SVSEELGPGRSGDAE-
---------------EPL---------NSQENAAAQSSLGPGEEA-------AVAAEARG
SEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SA

PF04130 // ENSGT00850000132278_2_Domain_2 (1737, 2024)

ADET
AVQLSELLTLPVLMKHSIMAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVSGLALNVVITEG-----------LPDLKLMMWALKGS-----
-SA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLPRNRDYFLNNKHVGRNVPYSGYDCDHLSVFETDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDSCGDRFERDTRVSLFGALVHSRTDDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGI
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQTFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQGLIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
M-SEAHQPQE--PPDVLVS-VHPQVASP----GPED---------PEGDQGCDAGP---A
-EQHSAAWDGRNRPGLPTPQSLKPL-----AM-GAGGT-GLQQA-EAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEATA
AASTQPSRPQEYDFSTVLRPAVAASPAPGPLQAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRAALKEGSSQPAEQLFGHES----------GGGLPT
GGCASETALTRPQW-NIHGHV---SDASIGV--------------GENVSEVAPTRPRWN
IHGHVSDASI-------------------------------RLGESVSEVAPTRPRWNTH
GHVSDASIRVGENVSDVAPTRPRWNTHGHVSDASII-----------------------L
GEPVWDVVPTRPRWNTHRHVSDA-------------------------------------
----------------------SISFGEPVSDVVSTRPRWNTHAPVPPPHMMLGAVSPEA
EPNT-----PRPQQSPAGHTSQSALS----------------------LGAQSTVLDCGS
----RLPVEVG-----PSLSSLSSGCGEESI-----------------------------
---------SIRENVSDMAPTQPW------SPNT---PGD----GVSEELGPGRSGDTE-
---------------EPL---------NSQENAAAQSSPGPGEEA-------AVAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRRVNRKRAKQSLKRVAYNALFTNLFQDEMHQLQ
PDLSKLPVRNKILMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPVAEVGSVLDLLVQ
LAGSGPPQVLQRKRGYFLNNKHVGRNVPYGGYDCYDLSVFEMDIQSLISREESLCHSMTQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCSDRFERDTRVSLFGALVHSRTYDMDIRLDLPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEPSKR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-SCRLRQGELQML-SGGL
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DALNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTYYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTALPGASGGGP-----RAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAYDVYVCGK-TINLLKLCCPRHYLCSSDTPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSISKEEKELRMEIAKQELIVHAREAASRVLSALSD
RQMSEQMALDARKREQFQRLKEQFVKDQERRRAARQEELDDDFSYARELRDRERRLRALE
EELERKARQALVDHYSKLSAEAARREQRALWRIQRHRLESARLR-FLVEDEKRIQGMLTD
V-SEVHKPQELL------------AVSL----GPEH---------ADGGRGCDSRL----
REQHLAAWHCPSRPSMPTPQLLEAAAVGAGGT-GP-------------------------
QQVAG------------------AEQPVQTSEVPLLEEVLQTIGSDPPSSA---LGETPA
AASTQPSELQEYDFSTILRPAVATAPSPGPFLAAEGCLGSLEQPVWGDTCMQLD-ARVPD
TQV------------ALPQPQPPDHVSP-DGSSRPTEQLCGHLS----------GAGVPT
---------------------------------------------EGCAPGTAPSRPRWN
IHGHVSDASIRVGENVSDVAPTRPRWN---VHGHVSDASI-RVGENVSDVGPTRPRWNVH
GHVS---------------------------DASIR-----------------------V
GENVSDEAPTRPRWNVHGHVSDASIRVGENVSDVAPTR-----PRWNVHGHISQSHMLPG
PLSPEAEPNIPTPH----------------------------------------------
-------------QIPPGQLSQAGLS----------------------LGTQSPALEHGP
----QSPVETVLSICSS-------------------------------------------
-------------------------------SSGSR-----------EESSPGRSGGAE-
----------DLSPSWPL---------NPQEDTAAPSSPGCGKEA---------EARRWG
REQAYLAGLARQYPLEQYPDSYECMSEPPAAHLLHHVRPRAFAFPVDPHVQ---SAADET
AVQLSELLTLPVLMKRSLTAPLAAHISLVNKAAVDYFFVELHLEAHCEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQYSLHGDTPHAANLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNMVITESCLGQYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----LVSHVAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLAAVRD
LEDIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SVFSLVLKFRSQLMAQAWGPAGGPRGAEHPNFALLQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAQ--PRPGQRSVDRKRTKQSLKRVAYNALFTNLFQEDARPLQ
SDLSKLPVRNKVLMLSFDLRVGGLGPEADRLEELVEGLEAAP--CCPLLEVGSVLTLLVQ
LAGSGPPQILQRKRDYFFNNKHAGRNVPYSGYDCCDLSVFEMDVQSFISREEHLCHSMIQ
ETLQVMEAAPGTALPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLDFPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSMTPDVDLWEAALT
YEVSKR------RCWERIG-CPP-GHREEPYLTEAGRDTFDR-FCRLRQEELQVL-SGGP
LQAPRPVLVTEQELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 1997)

DSLNVL-LGVASATFSLCQPAQAFVVARGVHVSGASPESISSIL
SEVAAYGTCYTRLSHFSLQPALGSSCSRGLVFQAFTSGLRRYLQYYRACVLATPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAMLLGTGGGEP-----RAVFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIRDWVYSGVLGDVYGEFMIQGNDEYLGCRDKSYWTH
GFALISKEVEDCVPVFLRHVAHDVYICGK-TINLLKLCCPQHYLCWSDIPVPRISVIFSL
EELKEVEKDCAVY-VGRMERVARHSSISKEEKELRMEIAKQELIAHAREAASRVLRELSD
RQTSEQMALDTRKREQFQRLKEQFVKDQERRLAARQEELDEDFSYAPE---------ALE
EELEKKARQALVDHYSKLSAEAARREQKALWRVQRHRLGSARLH-FLLDDEKCLQEMLRD
M-SEACRPQE--PLGVLPL-ARSQV--L--SASPEH---------SDGGQSCDPGP----
---PKQPEDYLGRLNAPALQPLQSP------------------AEGARPFSAGLSITDFL
PAGSG------------------AEQPVQD-GTPLLDHALQAICSDLFLSP---TVKAPS
AEGTLPVQPQEYDFSTILRPAPIALLSPESPQ-AV--KGSEEQQLWVDTRVTPD-ECAPD
TQVPL------------PCPLR--HGATQESSSQPPGWS---------------------
------------------------------------------------------------
PSTTLE-ATAPAEDCAAGTAASRPRWN---IHGHVSDASI-RVGENVSDVAASRPRWNVH
GHVSDASIRVGENVSDVAASRPRWNIHGHVSDASIR-----------------------V
GENVSDVA---------------------------ASR-----PRWNIHGHVSDASIQIG
ETVSDVASSWPCWDAHTT---------------------------QPT--------FLEP
-----ESNPPRLPYSRPSHRSQPGSL-----------------------EIESPALECGP
----PLRTEAE-----PATRSPGAGS-----------------------------WEDGG
VQDLPF------------------------AVAKPGALGE----SVLQEPGPGWSRDTE-
----------DLSPRRPL---------DSQEDTAAPGCPGPGEVE--AEADTEVEARRQG
EEQAYLAGLARLYHLEQYPDSYEAMSEPPVAQLVHHVLPRAFTFPVDPQVQ---PAVGET
AVQLSELLTLPVLMKCSLTAPLAAHVSLVNKAAVDYFFVELHLESHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLALNCILSKALQCSLRGDSPHAAGLSFALKHLPEV
FAPNTPDVLSCLELRYKVD-WPLNIIITESCLSKYGAIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHAAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFRARLATVSN
LEEIQRAHAEYLHKAVFRWGAAMGGVGVLGVEGGAAHCAHAHLR-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPATGPQGTEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKGNPPLRWAGRWPGWGTC--------------
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLPRNRDYFLNNKHVGRNVPYSGYDCDHLSVFETDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDSCGDRFERDTRVSLFGALVHSRTDDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGI
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNTNS------RTGHH
GYVLISKEVEDS-------HCHDVYVCGK-TINLLETLLPPALSLLVRRPVPGSPVIFSL
EELKEIEKDCAVY-VGRMES-----SVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
M-PEAHQSQE--PPGVLVS-LHPQVASP----GPED---------PEGDQGCDAGP---A
-EQHSAAWDGPNGPGLPTPQSLKPL-----AM-GAGGT-GLQQAEEAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAVAASPAPGPLQAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRAALKEGSSQPAEQLFGHES----------GGGLPT
GGYASETALTRPQW-NIHGHV---SDASIGV--------------GENVSEVAPTRPRWN
IHGHVSDASISLGESVSEVAPTRPR-------------------------------WNTH
GHVSDASIRVGENVSDVAPTRPRWNTHGHVSDASII-----------------------L
GEPVWDVVPTRPRWNTHRHVSDA-------------------------------------
----------------------SISLGEPVSDVVSTRPRWNTHTPVPPSHMMLGAVSPEA
EPNT-----PRPQQSPAGHTSQSALS----------------------LGAQSTVLDCGS
----QLPVEVG-----PSLSSLSSGCGEESI-----------------------------
---------SIGENVSDVAPTQPW------SPNT---PGD----GVSEELGPGRSGDTE-
---------------EPL---------NSQENAAAQSSPGPGEEA-------AVAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITDGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

------------------------------------------------------------
--------------TGSGARVPCSGAEADRLEELVEGLEAAP--RQPLAELGAVLELLVR
LAGSGPPRVRRRRRGVFLHSRPVGRALPYGGYDCADLSELEADVRSLISGEESLCRDLVR
KTRAWTCPRCRTAQTSP---------DWPSRPEAHASVFLYLPFSHFP--CLPVDVYLVN
HPLPLHFVAL------LLQVPPSVDQSEDEGFQSASNLTPDSQSEPGVTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQGELQVL-GGSL
LQAPQPVLVKECEL

PF04130 // ENSGT00850000132278_2_Domain_0 (375, 1997)

VKDALNVL-IGVVSATFSLCQPAQTFTVKRGVHVSGASPESISSLL
SKVAECGTHYARLSHTLLSDPP--------APQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRQLKAELLEVQAVLKQAGGGPGVCPPRAPPPPRGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGLRDRFYWTH
GYVLISKEAEDCVPMFLSHIAHDVYVCGK-TINLLKLCCPQHL---SDVPVPRISVVFSL
EELKDIEKDCATY-VGRMERVARHSSVSKEEKELRMEIAKQELIVQAREAASRVLQALSD
RQMSERMVSDAAGPEGSTSLAGRLWGVLQRRRAARQEELDEDFSYARELRDRERRLRALE
EQLERKARQALVDHYSKLSAEAARREQRALWKVRRHRLASARLR-FLLEDEKRIQGMLEA
M--AEGRPLE--QPAVLPG-ACSQTSAHS--WAGDQASFLGP-VPHDRGGSCDPGREE--
--PREAAPAGPHGQSVLTLQPLESPGAEAYR-----------------------------
------------------------------------------------------------
--------------------------------------------PQEDTQVPLD-TYGPD
PPQH---------------------PSPQEERCPATAQVLG-------------------
--------------------------------------AEPGVPRGVCASGMTPSRPRWK
------------------------------VHGHVSDASI-RVGENVWDVAPSRPRWKVH
GHVSDASIRVGENVWDVAPSRPRWNVHGHVSQSSVMLGVLSGEAEPNLS-----------
------------------------------------------------------------
------------------------------------------------------------
----------RPPLGPPDPGPQLGLS----------------------SGAQG----HMP
----RLPAETASGSSSAQVAGPGPGHGE-GG-----------------------------
PQASLS------------------------AEAVPAALGD----STPEEPGTALSWDWAG
R--------VRSASWSLL---------SDEEDADVQSSPDPGEA----------AAQLWD
REQAYLAGLAGHYRLEQYPDSYEAMSEPPVARLLHHGLPRAFALPEDARVP---SDADES
AVQLSELLPLPVLMKHSVTAPLAAHVSLVNKAVVDYFFVELNLGAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLVLNSVLSKALQYSLHGDSPHAANLSFALKFLPET
FAPNAPDVLSCLELRYKVD-WPLNIVVTEGCLSRYGGLFSFLLQLKLMMWTLKDVCFHLK
RTAPRSCWGSQAAGSAQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFQARLASVGD
LEEIQRAHAEYLHKAVF--------------------------S-RAALAAGL-------
-------------GGRPGGDTARPR-----------------------------RVPAQG
GLQVSCGLPPRG-----PGSSASTATPRSP---RAG--YQPHLEDFLLRINFNNYYQAA-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------GYDYYDVSMFEADARFLIASEEQQCRDMIQ
KTLQVMEAAPGTGLPSI--GLFAQNYPGVDRFERETHGSLFGALVHSRTYDMDVKLDLPP
VPDSADLSGL------AIQVPQSIDQSEDEGFQSASNLTPDSQSEPSMTPDIDLWDAVLT
YEPSKR------RCWERIG-CPP-GNKEEPYLTEAGREAFDM-FYRLREGELQLL-HSSL
LQLPPLFLMKERE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDVLNVL-IGVVSATFSLSQASQVFEVKQGVYVSGTSPQNMSSLL
SEVAEYGTHYTRLSRFSLQPVLDSSYSKGLVFQAFTSGLRKYLQYYRACVLSTPPTLSLL
TISFLFKKLGRQLRYLA-ELCGVGTAVLGSEGGA-------KSFPNGVKLLSYLYQEALD
NCSNEHYPVLLSLLKASCEPYTRFIHDWVYSGVFRDVYGEFMIQVNEEYLSCRDKFYWTH
GYVLISKEVEDCVPVFLRHVANDVYVCGK-TINLLKLCCPRHYICWSNIPVPRISVIFSL
EELKEIEKDCAVY-VGRMERLARHSAVSKEEKKLRMEIAKQELIVHARDTASRVLKALND
RHVSERMALDAKKREQFQKLKEQFLKDQERRLAAKQEEIDDDFSYARELRDREKRLKALE
EELEHRARQDLIDHYSKLSEEATRREQRAVWKIQRHKLETARLN-FLLEDEKRLQLVQVD
R-A---------------------VPLP----G---------------------------
---------------------------------------------------SSLDMNDFL
PMCLR----------------------PPTASGPSLEAALQTISLNLSPATASGHGA---
---GRQQQQSLYDFTTVLRPVAKSLFSAKRTPST----QGHQP-----------------
------------------------------------------------------------
-----------QRWG-LYGHAIPHSGESIRK--------------SPRSHVPVSGRARWD
------------------------------IYGHVSASHI-KMGECGTDMEPPPSRGGVH
GHVSDSNIPLGACISEVVSSRPRWNLHGHASQSHMK-----------------------L
GDLTVDVEAPRPRCSAFGHASQSSSWARV--SFPPPKP----LSRHLTPT----------
ATTSTMQWFLYNRE-LGC------------------------------------------
----------------PGQGPRPGWA----------------------------------
------------------------------------------------------------
-------------------------------------PED----SLCP------------
-------------PH-------------LPEEAETPTTPA---------E--ESKMEPKT
GEEAYLKALSDQYCLEKYQDNYNLMSEPPVSHLMHHIIPRLFSFPVDPHGP---LATDET
SVQLSELLTLPVLMKHSITAPLVSHVSLVNKAVVDYYFVELSLEKHFEALRHFLLMEDGE
FAQSLSDLLFEKLGSGQSPGEFLNPLVLNSFLTKALQYSLHGDTKLATNLSFALKYLPEV
LTANAPDALSCLELRYKVD-WPLNIVITESCLNKYNKIFSFLLQLKHMMWTLKDVCFHLK
RTA----LVNHAAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWREFGNKLSSVSN
LEEIHRTHAEYLNKAIF--------------------------R-GLLTEKAAPVMNVIH
SIFSLILKFRTQLISQAWTYDSSRQVAMHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRMNFNNYYRGTA
MAPQ------------------------

MASITQLFDDLCEALLPRAK--AHLGQRRVSRQRAKRSLKRVAYNALFTNLFQDETRKLQ
PDLAKLPLENKVLMLSFDLRVGGLGPEADRLEELVETLVAAP--CCPLAEVGSVLDLLVR
LAGSGPPQVLRRRRDYFFNNKHVGRNVPYGGYDCCELSVFEMDVQSLISREEQLCQDMIH
KALQVMEAPPGTGLPSV--GLFSYGDPCGDRFERDTRVSLFGALVHTRTYDMDVRLDLPP
VPDSAELSGL------AIKVPRSVDQSEDEGFQSASNLTPDSQSEPGTTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQGELQVL-GGGL
LQAARPVLVKEHE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDALNVL-IGVVSTTFPLCQLTQAFVVKQGVHVSGTSPDSISSLL
SEVAECGTHYARLSHFSLQPVLDSSCSEGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLI
AIAFLFRKLGRQLRYLA-ELCGIGT------CGEP-----RAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGFRDKSYWTH
GYVLISKEVEDCVPAFLKHIAHDVYVCGK-TINLLKLCCPQHYLCWSDVPVPRISVIFSL
EELKEIEKDCATY-AGRMERVARHSSVSKEEKELRMEIAKQELIVQAREAASRVLSALSD
RQMSERMASDARKREQFQRLKEQFVKEQERRRAARQEELADDFSYARELRDREQRLKALE
EQLERKARQALVDHYSKLSAEAARREQKALWKTQRRRLASARLR-FLLEDQERVQAMLID
V-SEGKS---LEPTAILPR-AHSQASSL----GSEH---------PDGGSSCDPGC----
AEQRVAVQDSASRPTQPLE----HAPGGACG---------LGQARVPGPFSADLSLQDFL
PPGQG------------------AEQPAHTAAAAVL-EALQTIGSDLPSSV---PST---
AVGTGPSGPQEYDFRTVLRPAVVPSASPGSLQTVGDRLGCEGLQLCGDMHVQLD-TCVPD
EQV------------ALPYPHLPSNTAQEE-----SSQAMGHVS----------EGAVPS
---------------------------------------------GGYASGMASSRPRWN
VHGHVSDASIKVGENVWDEVPTRPRWN---VHGHVSDASI-RVGENVWD-----------
------------------------------------------------------------
------EVPTRPRWNVHGHVSDASIRVGENVWDEVPSR-----PRWNVHGHVSHSHMMLG
VLSGEAQSAEARPR----------------------------------------------
-------------QHSPDHLSLSVLS----------------------LGAQSPAWDSVP
----GLPTELASDGSCSSIWSGPKENV------------------------------APR
PRRLLWPG--AL-------------------GDSIP-----------EEPGPGRNGDSE-
----------DLSPSWPS---------KSQGSVATQSSPGLEEEEE-------AGAAAQA
REEAYLAGLAGQYRLEQYPDSYEAMSEPPIARLLHHGLPRALALPEDPRGQ---SDADET
AVPLSELLPLPVLMKHSITAPLAAHISLVNKAVVDYFFVELRLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLVLNAVLSKALQYSLHGDSPHAANLSFALKFLPEA
FAPNAPDVLSCLELRYKVD-WPVNIVITESCLSRYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----LASPAAGSVQFRQLQLFKHEMQHFVKVIQGYVASQILHVTWCEFRARLAVVGD
LEDIQRAHAEYLHKAVF--------------------------R-GLLTERAAPVMNIIH
SVFSLVLKFRSQLISRPWGPA------EHPNFAFMQQSYSTFKYYS--------------
------------------------------------------------------------
----------------------------

MASITQLFDDLCEALLPAAK--TYLGQRSVNRKRAKRSLKKVAYNALFTNLFQEET-RLQ
PDTSKLPARNKILMLSFDLRVGGLGPRADRLEELVEELEAAP--SCPLVEVGSVLDLLVQ
LAGSGPPQVLPRKRDYFLNNKHVGRNVPYGGYDCYNLSVWERDVQSLISREEYLCHSMIQ
DTLQVMEATPGTGLPTV--GLFSFGDPCGDKFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDNADLSGL------AIKVPQSVDHWEDEGFQSASNLTPDSQSEPSVTPDMDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGREAFDK-FCRLRHGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQLAQAFMVKRGVHVSGASPESISSLL
SEVAEYGTCYMRLSRFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLATPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGGALPGTCGGGP-----RAEFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDTYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESVRLR-FLLEDEKRIQEMLKA
M-PEAHQSRE--PPDCLLS-PHSQVT-S----GPEH---------PDGGQGCDSGT---A
-EQHSASCDCPNRPNLRTPQPPKPS-----AV-GAGGT-GLQQAEEPGPFSDGLSIGDFL
PVGPG------------------AEQSVQTGTVPLLEAALQTISSDLPASA---PGEAPA
AASTQLAKPQEYDFSTVLRPAVAASPSPGPLQAAECSLGGSGLQPWEDTGGKLD-ACVSA
L---QVA---------LPPSQPPRCAALEEGSSQHTQQLFGHVS----------GGGVPT
RGYNSGIAPTLPRR-NTQGHL---SDASIRV--------------GEQMSDVAPTRPRWN
IHGHVSDASIRVGENMSDVAPTRPRWN---IHGHVSDASI-RVGENVSDVAPMRPR----
-----------------------LNIHGHVSDASIR-----------------------V
GENVSDVAPTR--------------------------------PRWNIHGH---------
------------------VSDASISLGGCMSDVAPTWPRWNTHGPIPPPHVMLGSLSPET
EPNT-----PRPQQSLPGHMSQSAPS----------------------LEAQNAALDCGP
----QLPVEVG-----PSLSSPSLGCGEESV-----------------------------
---------SMGENVSDVAPTQPC------WPNT---PGD----SISEEPGPGRNGDTE-
---------ELS-SNWPL---------NSQEDTAAQSSPGPGEEA----------AEAWD
GEQSYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPMFPRAFAFPVDTQVQ---SAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHTSSSVQFRQLQLFKHEMQHFVRVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWVPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQEET-QLQ
PDTSKLPARNKILMLSFDLRVGGLGPRADRLEELVEELEAAP---CPLVEVGSVLDLLVQ
LAGSGPPQVLPRKRDYFLNNKHVGRNVPYGGYDCYDLNVLERGVQSLISREEYLCHSMIQ
DTLQVMEATPGTGLPTV--GLFSFGDPCGDKFERDTRVSLFGALVHSRAYDMDVRLDLPP
VPDNADVSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSVTPDMDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGREAFDK-FCRLRHGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQLAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYLRLSRFSLQPVLDSSYSKGLVFQAFTSDLRRYLQYYRACVLATPPTLSLL
TIAFLFKKLGRQLRYLA-ELCGVGAALPGTCGGGP-----GAEFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDTYGEFMIQVNQEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYICGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIREMLKA
M-TEAHQPQK--PPDFLLS-PHSQVT-S----GPEH---------PDGGQGCDSGT---A
-EQHSASWDCPNRPDLRTPQPLKPL-----AV-GAGGT-GLQQAEEPGPFFDGLSIGDFL
PAGPG------------------AEQSVQTGVVPLLEAALQTISSDLPASA---PGEAPA
AASTQPSKPQEYDFSTVLRPAVAASPSPGPLQAAECSLGGSGPQLWEDTCGKLD-ACVSV
L---QVA---------LPPSHLPKCAALEEGSSQHTEQLFGHVS----------GGGVPT
VGYSSGIAPTQPRW-NIHGHV---SDASIRV--------------REQMSDVAPTRPRWN
IHGHVSDASIRVGENVSDVAPTRPRWN---IHGHVSDASI-RVGENVSDVAPTRPR----
-----------------------LNIHGHVSDASIR-----------------------V
GENVSDVAPTR--------------------------------PRWNTHGH---------
------------------VSDASISLGVCVSDVAPTRPRWNTHGPIPLPHVMLGALSPET
EPNT-----PRPQQSLPGHTSQSALS----------------------LGAQNAALDCGP
----WLPVEVG-----PSLSSPSLGCGEESF-----------------------------
---------SVGENMSDVAPSKPC------WPNT---PGD----SVSEEPGPGRNGDTE-
---------ELS-PNWPL---------NSQD-AAAQSSPGPGEEE----------AEAWD
GEQAYLAGLVGQYHVERYPDSYESMSKPPIAHLLRPMLPWAFAFPVDPQVH---SAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVRVIQGYIANQILHVTWCEFRARLATVGD
LEQIRRAHSEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SVFSLVLKFRSQLISQAWVPAGGPQGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEAHLPAAR--ASLGQRGLDRRRAKQSLKKVAYNTLFTNLFQEETHKLQ
PEPPKLPVKNKILLLSFNLRVGGLGPEADRLEDLVEGLEAAP--WCPLVEVSSVLDLLVQ
LAGRGPPQTLPRTRDYSLNNRRVGRNAPYSGYDCQDLSVSEMDVWSMISREEHLCHDMVQ
RTLQMMEAAPGTGLPTF--GRFY-G-DSGDQFERDTRASLFGALVHSRTFDMDVRLDLPP
VPDGADLAGL------AIKVPQSVDQSEDEGFQSASNLTPDSQSEPSVTPDLDLWEAVLT
YEPSKR------RCWERVG-CAP-GHREKPYLTEAGRDAFDR-LCRLCEEGLQVL-GGSL
LPVPPRVLVPECE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDVLNVL-LGVVSATFSLSQPAQAFVVKPGVYVSGTSPESTHSLL
TEVATCGTYYVRLSHFSLQPVLDPTCSKGLVFQA-TSGVRRYQ--YYRCVLATPPTISML
AISFLFKKLGRQLRYLA-ELCGVGTGPPGASSVGP-----RTAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTQFIHDWVYSGLFRDIYGEFMIQV-HDYLGFRXXXXXXX
XXXXXXXXXXXXXXXX-XXXXXXXXXXXX-XXXXXXXXXXXHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARCSAISKEETELRAEIAKQELIVHARVAASEVASALSA
QQASERLAVDAQKREQFQRLKEQYLRDQERRFAARQEEARDDFSCTLEFREREKGLQALE
REREQRNRQELVEHYRQLSAEAARREQKALWRLQRRRLAEARRH-FLQAEQTRLQELLKD
V-SEVDKLQYSALAW-V--RGHPQAPS------PDV---------EPSGRGQDRGPSP--
AEEHRIV---------PKPWSP------------------ESPTVGFEPFSAGLSIQDFL
PTGPG------------------VKQPAEPSVVPLLERALRTVRSDVPSLA---PGDVPP
VGITEGSQGQTYDFSTILRPAVAASASSEPRPSAEASLGSKEPQLQWDTHQRLG-AQVPE
GLA------------AQPHLPQPTLGPAEDGGSRPQDQLLQRMS----------ER----
---------------------------------------------------SAPCRPQWS
VHGHVSDANSRAEENISDVAPSRPQWS---VHSHVSKANI-RVGENVSDVAPSRPRWNVH
GHVSEANIRVGENISDVAPSRPRWNVHGHVSKANIR-----------------------V
GENVSDVTPSRPRWNVHGHVSKANIRVGENVSDVAPSR-----PRWSVYGHVSDANFRIG
ENTSDVAPSWPQWV----------------------------------------------
-------------SMPPSHRMTGVLSEEAEPETVGLPLSTAGNMVPSDLGAQSLSPEQEP
----RPPAEREP------------------------------------------------
-ALESCPG--SGGCL------SSAEEGA--SGEVLWRPGTPQEHGSEGEPDPRSSSSSS-
----------APSPGHPS---------SPQAGEVAQGSPMP---------------AEDK
EEQAYFKELAARYRLEQYPDHYEAM-EPPAAQLLPRMLARTFSFPADHQAR---PGTDES
AVQLSELLTLPVLLKHSISAPLAAHVSLVNKAAVDYFFMELHLETHLEALRHFVLMEDGE
FAQSLSDLLFEKLGSGQTPGELLSPLALGSVLSKALQYSLHGDSPLAANLSFALKFLPEV
FSPNAPDVLSCLELRYKVA-WPLNIVITESCLSQYGRVFSFLLQLKLMTWTLKDVCGRLK
RTA----LASRAAGSVQLRQLQLFKHEMQHLVKVTQGYIASQILHVTWREFRDKLATVST
LEEVQRAHAEYLNKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLIAQAWGPATCPRGAEHPNFALMQQSYSTFKY-SHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAQ--ARPGQRSVNRKRAKLSLKRVAYNALFANLFQEETHQRQ
PDSSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEAIP--GCPFVEVESVLDLLVQ
LAGSGPPQVPRRKRDYFFNNKHAGRNVPYSGYDCYDLSVSEMDVRSLISGEEYLCHNMVQ
ESLQVMEAAPGTGLPTV--GLFSIGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDMPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWETVLT
YEASKR------RCWERIG-CLP-GHREEPYLTEAGRDAFDR-FCRLCHGELQAL-SGGL
LQGPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQPTQAFVVELGVHVSGASPESISSIL
SEVAEYGTYYTRLSHFSLQPVIGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSLAT-SGEP-----KAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSISKEEKELRMEIAKQELIVHAREAASRVLSELSD
RQMSEQMAVDTRKREQFQRLKEQFVKDQERRLAARQEEIDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDQKRIQEMLRD
M--EAHQSQE--PPRVFPS-TCSQITSP----CPEH---------AAEGRSCDLGS----
---TELQWDCLSPPGISTPSALKSA-----AE-GADDS-GA----EVGPFSSGLSITDFL
PTGPG------------------TEQPMDNTGAPFLEAALQTICSDLPPIT---PGPA-L
TAAGPQPTQSEYDFNTILRPALAASSSPGSFQDVQNGLDSEKKHVLGDMPTKLN-ACVHD
MQ------------ETLPGSHPLKHVTPEEGSVQPVGELIEHMS----------GIVVPT
ESLASGMAPCQQLR-SISRCV---SDASIQQ--------------GDNMSDVALPQPQWS
IRGHVSEASIGVGENVSEVASSRPRWN---VHGHVSDASI-KVGEN--------------
------------------------------------------------------------
------------------------------------------------------------
---------VPRWNVHGHVSDASIRIGESVSD--EAL--QPDGCT-QP-PLILEEPLPEA
EPD-----LLKPHQGSPAHVFQSGLG----------------------AEAQSPALECGA
----QLPGERK-----PTICSS-RGSTEEGSL----------------------------
----------------ETKPP---------AVAEPSTLGN----GIPEETGPGRSRDAQ-
----------DLSPWPP----------SSQEDAAVPSSPGSSEEVSDIEA----EARRWS
KEQTYLADLTKLYRLEQYPDSYESMSEPPVAHLVHHMLPQAFAFPVDPQVQ---SAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVSLVNKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHATNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMVWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVSD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQTWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASITQLFDDLCEALLPPAK--ARPGQRALSRPRAKRGLKRVAYDALFAHLFRDEAP--P
PEPPKLPVRNKILMLSFDLRVGGLGPEADRLEELVDGLEAAA--SGPLREVRAALDLLVL
LAGSGPPQGLPRRRGYFLGGPHVRRRVPYGGYGCCDLRAAEADVWALLAREESLCHSMVQ
ETLQVMDAAPGTGLPTL--GLFS-GDACGDRFERETRVSLFGALVHSHAYDMDVRLDLPP
VPDSADLSGL------AIKVPPSLDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YESSKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGDLQVL-SGGL
LQAPVPLQVEEREL

PF04130 // ENSGT00850000132278_2_Domain_1 (375, 650)

VKDVLNIL-IGVVSASFSLCQLTQAFVVKRGVHVSGASPESVGSLL
SEVAEYGTCYMRLSRFSLQPVSDSAYSKGLVFQAFTSGLRRYLQYYRACALSTPPTLSLL
TIGFLFKKLGRQLRALW-GGGA---------VGAS-----SAAWPGAVWGPALLLGRGLD
NCSNEHYPVLL-LLKTSCEPYTRFIHDWVYSGVFRDFYGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEDCVPVFLRHIAHDVYVCGK-TVNLLKLCCPRHYLCWSNIPVPRISVIFSL
EELKEIERDCAVY-VGRMERVARHSSVS--------------------------------
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----------------------------------------------------LTPGEVPT
LAGTQPSQVQEYDFST

PF04130 // ENSGT00850000132278_2_Domain_0 (1037, 1972)

ILRPAVAALVSPGSLQALEGDSGSKGPQLRWDTDTKLD-ARVPE
V--------------LAGQPHLPLPRPAEEENSGPQDQPLRHVS----------EGRVSS
VGHASQTAPSRPRW-SVHGHV---SDANIKI--------------GENVSDMAPLQPRWN
IHGHTSDANVRVGENVSDVAPSRPQWS---VHGHVSDANI-RVGENVSDVAPSRPRWSVH
GHVSDANIRVGENVSDVAPSRPRWSIHGHVSDANIR-----------------------V
GENISDVAPSRPRWSVHGHVSDANIRVGENVSDVVPSR-----PRWSVHGHVSDSNIRVG
ENVSDVAPSQPRWSVHGHMLLEEAEPEKS-------------------------------
----------GPHLSPSGHVVQSD------------------------QGAQSTSLEHPP
-----AETTPG-----PLGLS---------------LAQVATFGSAE----------EGG
FQAEL---------CTVARPGAPEEHGSEGEPADA--PSL----PHCARSGSRSSGN---
--------SSTASPGQPS-------------------SP---------------QAGEAR
EEWAYLEGLAAQYHLEQYPDSYEAMSEPPAAHLLPHVLPRSFSFPADPQAQ---PGTDET
AVQLSELLTLPVLLKHSISAPLTAHVSLVNKAAVDYFFVELHLETHLEALRHFVLMEDGE
FAQSLSDLLFEKLGSGQMPGELLSPLALGSVLSKALQYSLHGDSPLAANLSFALKFLPEV
FSPNAPDVLSCLELRYKVD-WPLNIVITESCLSKYGRIFSFLLQLKLMMWTLKDICGHLK
RSA----LVSRVAGSVQFRQLQLFKHEMQHFVKVTQGYIASQILHVTWCEFRNKLATVST
LEEVQRAHAEYLNKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPTAHPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MTSITQLFDDLCEALLPAAQ--AHPGQRPVDRKRAKLSLKRVAYNALFANLFQEETHQRL
PDSAKRPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEATP--GCPLVEVESVLDLLVQ
LAGSGPPQVLRRKRDFFFNNKHAGRNVPYGGYDCYDLSVFEMDVRSLISGEEYLCHNMFQ
EALQVMEATPGTGLPTV--GCFSIGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQMMDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLT
YEASKR------RCWERIG-CPP-GYREEPYLTEAGRDAFDR-FCRLCHGELQAL-SGGL
LQAPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQQTQAFVVELGVHVSGASPESIRSIL
SEVAEYGTYYTRLSHFSLQPVVGSMCSRGLVFQAFTSGIRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSLVT-SGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYREFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMESVARHSSISKEEKELRMEIAKQELIVHAREAASRILTELSD
RQMSEQMAVDTRKREQFQRLKEQFLKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDQKRIQEMLSD
M--EAHQPQK--PPSVFPS-TCSQVTSP----GTEH---------ADEGRSSDLGS----
---TEQCWDCLSLPGASTPSTHKSA-----AE-GADNS-G-----GAGPFSTGLNITDFL
PMGPG------------------IEQPMDNIGGPFLEVALQTISSDLPPIT---PGPA-L
TAAGPQPAQPEYDFNTVLRPTLATSSLPGPFQDVQNSLDSEKQHLLGDMPTKLD-SCVHD
MQ------------ETLPCPHPLKQDTPEDGNSQPVGQLLEHMS----------ESAVPI
ESLVSGMAPCQQLR-SSSTCV---SDASIKQ--------------GDYMSDMALPRPQWN
IHGHVSEASIGVGENVSEVAPRRPRWN---IHGHVSDASI-RVGENVSDVIPSRPRWNIH
GHVSEASIKVGENVSDVTPSRPRWNVHGHVSEASIK-----------------------V
G---------------------------ENVSDVAPSR-----PRWNVHGHVSEASIKVG
ENVSDVVPSRPRWNVHGHVSEASIRIGENVSE--EAL--QPRDCT-QP-PLILEEPLPEA
EPD-----LLEPHQCSPARVSQSGLC----------------------VEAQSPVLECGP
----QLPKEMK-----PTTCSS-PGSTEEGSP----------------------------
-----------------TKPP---------VVAEAGTLRN----GIPEETGPGRNRDAE-
----------DLSPWPP----------SSQEDTAVPSSPGPSEELSDTET----EARRWG
KEQAYLADLTKLYHLEQYPDSYESMSEPPVAHLVHHMLPQAFAFPVDPQVQ---SAVDES
TVQLSELLTLPVLMKRSLTAPLAAHVTLVNKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHATNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQTWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTNLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MTSITQLFDDLCEALLPAAK--THLGQRSVNRKTAKRNLKKVAYSALFTNLFQDETQQLQ
LDMSKLPARNKILMLSFDLRVGGRGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLRRNRDYFLNNKHVGRNVPYSGYDCDHLSVFETDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPP
VPDNADLSGL------AIKVPPNVDQWEDEGFQSASNLTPDSQSEPSMTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAAQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELEDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHVQEMLKA
M-SEGHQPQE--PPDV-LS-VHPQVTSL----GPEH---------QEGDQGCDAGP---A
-EQHLAAWDGRNRPGLLTPQSLKPL-----AM-GAGGT-GLQQAEEAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAAAASPAPGPLKAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRATPKEGSSQPTEQLFGHES----------GGGLPT
GGCASEIALTRPQW-NIHRHV---SDASIRV--------------GENVSQVAPARPRWN
THGHVSDASISLGESVSEVAPTRPRWN---IHGHVSDASI-RVGENVSDVAPTRPRWNAH
GHVSDASISLGEP-----------------------------------------------
------------------------------VSDVVSTR-----PRWNAHGHVSDASISLG
EPVSDVAPTRPRWNIHGHVSDASISLGESVSEVAPTRPRWNTRASVPPPHMMLGAVSPEA
GPNT-----PAPQQSPPGHTSQSVLS----------------------PGAQSTVLDCGP
----RLPVELG-----PSLSSPSSGCGEGSI-----------------------------
---------SIGENVSDVAPTWPW------LPNT---PGD----SVSEELGPGRSGDAE-
---------------EPL---------NSQENAAAQSSLGPGEEA-------AVAAEARG
SEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSIMAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRRRAKRSLKKVAYNALFTSLFQEET-QLQ
PDTSRLPARNKILMLSFDLRVGGLGPRADRLEELVEELEAAP--CCPLVEVGSVLDLLVQ
LAGSGPPQVLPRKRDYFLNNKHVGRNVPYGGYDCYDLSVLERDVQSLISREECLCHSMIQ
DTLQVMEATPGTGLPTV--GLFSFGDPCGDKFERDTRVSLFGALVHSRAYDMDVRLDLPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSMTPDMDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGREAFDK-FCRLRHGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSVTFSLCQQAQAFVVKQGVHVSGASPESISNLL
SEVAEYGTCYMRLTHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLATPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAALPGTCGGGP-----RAEFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDTYGEFMIQVNQEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDAQKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSRLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKRIREMLKA
M-TEAHQPQE--PADFLLS-PHSQVT-S----GPEH---------PDGGQGCDSRT---A
-EQHSASWDCPNRPDLRTPQPLKPL-----AV-GAGGP-GLQQAEEPGSFSDGLSLGDFL
PVGPG------------------AEQSLQTGTVPLLEAALQTISSDLPASA---PGEAPS
SASTQPSKPQEYDFSTVLRPAVAASPSPGPLQAAECSF----------------------
----------------LPPSHPPRCAALEEGSSQHTEQLFGHVS----------GGGVPT
GGYNSGIAPTQPRW-NTHGHM---SDASIRV--------------REETSDAAPTRPRWN
IHGHVSDASIRVGENVSDVAPTRPRWN---IHGHVSDASI-RVGENVSDVAPTRPR----
-----------------------LNIHGHVSDASIR-----------------------V
GENVSDVAPTR--------------------------------PRWNTHGH---------
------------------VSDASISLGVCVSDVPPTRPRWNTHGPIPPPHVMLGALSPET
ESNT-----PRPQQSLLGHTSQSALS----------------------LGARNAALDCGP
----QLPVEVG-----PSLSSPSLGCGEERV-----------------------------
---------SMGENVSDVAPTQPC------WPNT---PGD----SVSEEPGPGRNGDTE-
---------ELS-PNRRL---------NSQEDAAAQSSRGPGEEE----------AEAWD
GEQAYLAGLAGQYHLEQYPDSYESMSEPPIAHLLRPMLPRAFAFPVDPQAQ---SAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVRVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWVPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNYYYQDA-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDVSKLPARNKILMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLPRNRDYFLNNKHVGRNVPYSGYDCDHLSVFETDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDSCGDRFERDTRVSLFGALVHSRTDDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
M-SEAHQPQE--LPDVLLS-VHPQVASP----GPED---------PEGDQGCDAGP---A
-EQHSAAWDGRNRPGLPTPQSLKPL-----AM-GAGGT-GLQQAEEAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAVATSPAPGPLQAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRAALKEGSSQPAEQLFGHES----------GGGLPT
GGYASETALTRPQW-NIHGHV---SDASIGV--------------GENVSEVAPTRPRWN
IHGHVSDASI-------------------------------SLGESVSEVAPTRPRWNTH
GHVSDASIRVGENVSDVAPTRPRWNTHGHVSDASII-----------------------L
GEPVWDVVPTRPRWNTHRHVSDA-------------------------------------
----------------------SISLGEPVSDVVSTRPRWNTHAPVPPPHMMLGAVSPEA
EPNT-----PRPQQSPAGHTSQSAFS----------------------LGAQSTVLDCGS
----RLPVEVG-----PSLSSLSSGCREESI-----------------------------
---------SIGENVSDVAPTQPW------SPNT---PGD----GVSEELGPGRSGDTE-
---------------EPL---------NSQENAAAQSSPGPGEEA-------ALAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLPRNRDYFLNNKHVGRNVPYSGYDCDHLSVFETDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDSCGDRFERDTRVSLFGALVHSRTDDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVGWCPP-CHREGALLTEAGRDAFRK-FCRLRQGELQLL-AGGV
LQAHSPVAGETV-----------------SSTPVQPAQAF

PF04130 // ENSGT00850000132278_2_Domain_0 (401, 2024)

VVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLSVSL---GG----------------------LGGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCC------WSQTPKLRREPLR--
--------------LARM-----LCLTSCLSQELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
M-SEAHQPQE--LPDVLLS-VHPQVASP----GPED---------PEGDQGCDAGP---A
-EQHSAAWDGRNRPGLPTPQSLKPL-----AM-GAGGT-GLQQAEEAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAVAASPAPGPLQAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRAALKEGSSQPAEQLFGHES----------GGGLPT
GGYASETALTQPQW-NIHGHV---SDASIGV--------------GENVSEVAPTRPRWN
IHGHVSDASISLGESVSEVAPTRPRWN---THGHVSDASI-RVGENVSDVAPTRP-----
----------------------RWNTHGHVSDASII-----------------------L
GEPVWDVVPTR--------------------------------PRWNTHRH---------
------------------VSDASISLGEPVSDVVSTRPRWNTHAPVPPPHMMLGAVSPEA
EPNT-----PRPQQSPAGHTSQSAFS----------------------LGAQSTVLDCGS
----RLPVEVG-----PSLSSLSSGCREESI-----------------------------
---------SIGENVSDVAPTQPW------SPNT---PGD----GVSEELGPGRSGDTE-
---------E------PL---------NSQENAAAQSSPGPGEEA-------ALAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

MASITQLFDDLCEALLPAAQ--ARPGQRSVNRKKAKLSLKRVAYNALFANLFQEDTHQRQ
PDS-KLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLETAP--DCPFVEVGSVLDLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNIPYSGYDCYDLSVFEMDVRSLISGEENLCHNMVQ
EALQVMEAAPGTGLTTV--GLFSTGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLT
YEASKR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-FCRLCHGELQAL-SGGL
LQTPRPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQPTQAFVVEPGVHVSGASPESISSIL
SEVAEYGTCYTRLSHFSLQPVVGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSLAT-SGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARYSSISKEEKELRMEIAKQELIVHAREAASRVLSELSD
RQMSEQIALDTRKREQFQRLKEQFVKDQERRLAARQEELGDDFSYAHELRAREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIRRHRLESARLR-FLLEDQKCIQEMLRD
M--EAHQPQE--PLSVLPS-TCSQVTSL----GPEH---------EGEGHSCDLES----
---TELRCDCSNQPCASTPSVLK--------------S-GAGQAEEAGPFSTGLSITDFL
PMGSG------------------DEQPVGDTGAPFLEVALQSICSDLSPIT---PGPA-L
TAGGLQPTQSEYDFNTILRPAMATPPLPGPFRDVQNSVDSEKQHLLRDMPTKPD-SCIHD
MQ------------ETLPCLHPLSHVTPAEGSLQPVGQLLEHMS----------ETTVAT
ESHASGMAPCQQL--SISRHV---SDANIKV--------------GDYMSDVALPRPRWN
IHGHVSEANIGVGENVSDVAPSRPRWN---VHGHVSDASI-KVGENVSDVAPSRPRWNVH
GHVSDASIKVGENVSEVAPSRPRWNVHGHVSDASIK-----------------------V
GE---------------------------NVSDVAPSR-----PRWNVHGHVSDASIKVG
ENVSDVAPSRPRWNVHGHVSEASIRIGENVSD--VDL--QPHGHV-QP-PLILEEPFPEA
EPD-----L-KSHQCPPDHVSQTVLC----------------------VEAQSPAQECEP
----QLPEEMK-----PTICLS-LGSTEEGSL----------------------------
----------------QTK-T---------LVTEPSMLGN----GIPEEKGPRRNRDAE-
----------DLSPCLPS---------SPQEDT-LPSSPGPSEEVPSTEA---EEARRWG
KEQAYLADLTKLYRLEQYPDSYESMSEPPMAHLVHHMLPRAFAFPVDPQVQ---SAVDES
AVQLSELLTLPVLMKRSLMAPLAAHVSLVNKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHATNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQNWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASVPQLLDDLCEALLPAAK--APLGQRGASRQRAKQSLKRVAYSALFTGLFQDETRRLQ
PGLAKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEELLAAP--RGPLLEVGSVLDLLVQ
LAGSGPPQVLRRKRDYFWNNRHVGRKVPYGGYDCYDLSVCELDVQSLISREEYLCQDMIQ
KALQVMEAAPGTGLPTT--GLFSYGDPCSDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADLFGL------AIKVPQSVDQSDDEGFQSASNLTPDSQSEPGMTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDAFDR-FCRLRHGELQVL-GGGL
LQAPQLVLVKECEL

PF04130 // ENSGT00850000132278_2_Domain_0 (375, 2024)

VKDALNVL-IGVASATFPLCQPAQTFTVKRGVHVSGASPESVSSLL
AEVAVCGTHYARLSQFSLQPVLDSSCGKGLVFQAFTSGLRRYLRYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAALPGSSSGEP-----GAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVCGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKVCCPQHYLCCSDVPVPRISVIFSP
EELKEVEKDCAIY-VGRMERVARHSSISKEEKELRMEIAKQELIVQAREAASRVLRALSD
RQTSERMALDARKREQFQRLKEQFVQDQERRRAARQEALDDDVGPARELCDRERRLRVLE
EQLEKKARQALVDHYSKLSAEAARREQKALWKIQRHRLASARLR-FLVEDQKHIQGMLKD
V-SEGKAPE---PLAVLPA-AGSQTLSS----GHEH---------PAGGSSSDSRCA---
EPQHVAAWDWL---NSRTPEQVRPPAAGAHGS-APGSELQPGSGDRPGPFSEGLSIQDFL
PRAQE------------------AEPPAHAGVTPVLEEALQTIGSDLPPSA---PSDV--
-VATGPAGTQEYDFRTILRPAVAPLASPGSLQTIGGGSSNEGQQLWRDSVPQPGNTGVPD
RHV------------ALLHPHPAGHTVPQEGSSQAMEQLLEHVS----------EGSVPI
---------------------------------------------GGCTSGMAPSRPRWN
VHGHVSDASIKVGENVWDVAPSRPRWN---VHGHVSEANI-KVGENVWDVAPSRPRWNVH
GH----------------------------------------------------------
-------------------VSDANIKVGENVWDVAPSR-----PRWNVHGHVSQSHVALS
ALSGEGQPDMPRPC----------------------------------------------
-------------QSLTDQVSRSGLS----------------------LGAQSPVCEHEP
----QMPTETASDSDSAQVAGSSGGEPHGLQALPSAAALSGDLGDGIPE-----------
------------------------------------------------EPGPVPSRDTE-
----------NLSPNHPL---------SSQDDVAAQSSPGLGEEA--------AAAQRWD
REQAYLAGLAEQYGLEQYPDSYEAMSEPPAAHLLHHGLPRAFALPEDPHVR---SDADET
AVQLSELLPLPVLMKHSISAPLAAHVSLVNKAAVDYFFVELRLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALRCSLHGDTPLAANLSFALKFLPEA
FAPNAPDVLSCLELRYKVD-WPLNVVLTEGCLSRYSGIFSFLLQLKLMMWTLKDVCFHLK
RAX----LVSRAAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVTWCEFRARLAQVGD
LEDIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQPWVPAGGPRGAQHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDDTQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHTMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDIYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
V-SEAHQPQE--PPDVLLS-VHPQVTSP----GPEH---------PEGGQGCDSGS---A
-EQHSPAWDGRNRPGLLTTQPLKPL-----AV-GAGGT-GLQQAEEARPFSDSLSIGDFL
PVGPG------------------AEPSVQTGMVPLLEVALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDSCGKMD-ACGSA
S---RET---------LLPSHPPRRAALEEGSSQPTERLFGQVS----------GGGLPT
GDYASEIAPTWPRW-NTHGHV---SDASIRV--------------GENVSDVAPTRPRWN
THGHVSNASISLGESVSDMAPTRPRWN---IHGHVSNASI-RVGENVS------------
---------------DVAPTRPRWNTHGHVSDASIS-----------------------L
GESVSDVAPARPRWNTHGHVSDASISLGESVSDMAPTR-----PRWNTHRHVSDTSIRFG
ENVSDVTPIRSRCNTHGHVSDASISLGEPVSDVVSTRPRWNTHVPIPLPHMALGALSPEA
EPNT-----PRPQQSPPGHTSQSALS----------------------LGAQSTVLDCGP
----RLPVEVG-----PSLSSPSSGCGEGSI-----------------------------
---------SVGENVSDVAPTQPW------WPNT---PGD----SVSEELGPGRSGDTE-
----------DLSPNWPL---------NSQEDTAAQSSPGHGEEAE------ASAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLPRNRDYFLNNKHVGRNVPYSGYDCDHLSVFETDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDSCGDRFERDTRVSLFGALVHSRTDDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
M-SEAHQPQE--PPDILLS-VHPQVASP----GPED---------PEGDQGCDAGP---A
-EQHSAAWDGRNRPGLPTPQSLKPL-----AM-GAGGT-GLQQAEEAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAVAASPAPGPLQAAECNLGSSGSQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRAALKEGSSQPAEQLFGHES----------GGGLPT
GGYASETALTRPQW-NIHGHV---SDASIGV--------------RENVSEVAPTRPRWN
THGHVSDASISLGESVSEVAPTRPRWN---THGHVSDASI-SLGESVSEVAPTRPRWNTH
GHVSDASIRVGENVSDVAPTRPRWNTHGHVSDASIS-----------------------L
GEPVWDVAPTRPRWNTHRHVSDA-------------------------------------
----------------------SISLGEPVSDVVSTRPRWNTHAPVPPPHMMLGAVSPEA
EPNT-----PRPQQSPAGHTSQSAFS----------------------LGAQSTVLDCGS
----RLPVEVG-----PSLSSLSSGCREESI-----------------------------
---------SIGENVSDVAPTQPW------SPNT---PGD----GVSEELGPGRSGDTE-
---------------EPL---------NSQENAAAQSSPGPGEEV-------ALAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQEET-QLQ
PDTSKLPARNKILMLSFDLRVGGLGPRADRLEELVEELEAAP--CCPLVEVGSVLDLLVQ
LAGSGPPQVLPRKRDYFLN-KHVGRNVPYGGYDCYDLSMLERDVQSLICREEYLCHNMIQ
DTLQVMEATPGTGLPTV--GLFSFGDPCGDKFERDTRVSLFGALVHSRAYDLDIRLDLPP
VPDNADFSGL------AIKVEFVFSLSSLSGKYPGAE----------------VQVARLL
MASP--------LPPLLLPLSPP-GHREEPYLTEAGREAFDK-FCRLRHGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSVTFSLCQLAQAFVVKQGIHVSGASPESISSLL
SEVAEYGTCYMRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLATQPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAALPGTCGGGP-----RAEFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDTYGEFMIQVNQEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKRIQEMLKA
M-TEAHQPQE--PPDFLLS-PHSQPLAP----GECRLGLMSCVFQVTSSQGCDSGT---A
-EQHSASWDCPNRPDLWTPQPLKPL-----AV-GAGGP-GLQQAEEPGSFSDNLSIGDFL
PVGPG------------------AEQSLQTGTVPLLEAALQTISSDLPASP---PGEAPA
AANTQPSKPQEYDFSTVLRPAVAASPSPGPLQPAECSLGGLGPQLWEDIHGKLD-ACVSA
L---QVA---------LPPSRPPRCAALEEGSSQHIEQLSEHVS----------EGGVPT
GGYNSGIAPTQPQW-NTHRLV---SDANIRV--------------GEQVSDAAPTRPRWN
IHGHVSDASIRVGENVSDVAPTRPRLN---IHGHVSDASI-RVGENVSDVAPTRPRWNTH
GHVSDASISLGVCVSDVAPTRPRWNTHGPIPPPHVMMGALSPETESNTPSLGCGEESTSM
GENVLALAPTVPQWNIEGHVSNTTISMGENVLDMAPSR-----PQWNIEGH---------
------------------VSDDTISMGENTSDVAPTRPCWPNTLGDS---------SWVA
DG--------------------RAWE----------------------VGGSCCLGDMGG
----AAWA----------------------------------------------------
------------RAGSALSPAQAL------GPDT---PM-----STCVHTGPGRNEDTE-
---------ELS-PNWPL---------NSQEDAAAQSSPGPGEAA---------AAEAWD
GEQAYLAGLSGQYHLERYPDSYESMSEPPVAHLLRPVLPRAFAFPVDPQVQ---PAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVRVIQGYIANQILHVTWCEFRARLATVGD
LEEMQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWVPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MAGITQLFDDLCEALLPVTR--ARPGLRSVDRKRAKQTLKKVAYNALFADLFQEDTRQLR
PNLPKLPVKNKVLMMSFDLRVGGLGPEADRLEELVEELQAAP--GCPFVEVGSVLELLVQ
LAGSGPPQILRRKRDYFK--KHAGRNVPYSGYDCCDLSVLEMDVRSLISREGYLCQNMIQ
ETLQMMEAAPGTHLPTM--GHFSFGDPCGDKFERDTRVSLFGALVHCRTYDMDVRLDLPP
VPDSADLSGL------AIKVPQSMDQWEDEGFQSASNLTPDSQSEPSMTPDVDLWEVALT
YEASKR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-LCRLRQGELQVL-SGGL
LQAPRPVLVKESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQPTQAFVVERGVHVAGTSPESICSIL
SQVAEYGTHYMRLSHFSLQPVQGSMCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
SIGFLFKKLGRQLRYLA-ELCGVGTALPGTTGGET-----RAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLALLKTSCAPYTQFIHDWVYSGVFRDVCGEFMIQVNHEYLGCRDKFYWTH
GYVLISKEAEDCVPVFLKHIAHDVYICGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
KELKEIEKDCAVY-VGRMERVARYNSISKEEKELHMEIAKQELIVHAREAASRVLRDLSD
RQVSEQMALHARKREQFQRLKEQFVKSQERLLAARLEEMDDDLSTAPELRDREKRLKALE
EELENKARQALVDHYSKLSAEAAHREQKALWRIQRHRLESARLR-FLLEDQKQIQGMLRD
R-SEAGQPQE--TLGILPI-SHDQVTSL----GSEL---------PDGGCGHESVP---T
E--QQAKQDCLSRPSAHTPQSPE-------SR-AVGDE-GS----SSEPFPAALNIVDFL
PMATG------------------SKQAVPDAGAPLLEEALQTICADLTPVA---PGQAPS
ATG-MHTTPVEYDFSTVLR-PT-VATLPSPR-------------LFQTIQGSLG-STEHP
SGHTQLKLDVCAYNTQKPLPYLLRC-VSPEADSQPIQQLLEQRAEAAPTEDCASGMAL--
---------SRPRW-SVHGHA---SDASIRV--------------GENVSDVAPARPRWN
VHGHASDASIRVGENVSDVAPARPRWS---VHGHASDASI-RIGENMSDVAPARPRWNVH
GHASDASIRIGENVSDVAPVRPRWSIHGHASDASIK-----------------------I
GENVSDVAPARPRWNVHGHASDASIKIGENVSDVAPAR-----PRWNVHGHASDASIRVG
ENVSDVAPQLLQDT-HGCNSQ----------------------CPMI-----PGVLSPEA
EPK-----SPRSP-------QNPGLT----------------------PETHSSALNCGP
----QLPEDVG-----PAFYPSSPSVVEGS---------------------L--------
----------------QTRPPAAA------EPRV---LGD----HIPEEPGPGENGDNGG
--------NADLSPDLPK---------NSEEETV---SPGCSEEAVDTDV--EAEARRQE
EEQAYLAGLARLYHLEQYPDNYESLSEPPLAHLVHHVLPQAFALPVDPQIQ---SAVDET
VVQLSELLTLPVLMKRSLTAPLAAHVSLVNKAAVDYFFVELHLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGEILNPLVLNCILSKALQYSLHGDTPHAANLSFALKYLPEV
FAPNAPDVLSCLELRYKVE-WPLNIVITESCLSKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSQVASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAAVGD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWSPTSGPRGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASITQLFDDLCEALLPAAQ--APLRPRGLSRRRAKQSLKRAAYNALFAHLFQEEPPRPP
PGRPRLPVKNKVLMLSFDLRVGGLGPEADRLEALVEKLEAAP--RCPLAEVGSALDLLVQ
LAGTGPPQVLPRRRDLFLNNKHVGRNVPYGGYDCYDLSVFEMDVQALIRREEYLCQDTIH
KALQVMEATPGTGLPTA--RLFSYGDPGGDRFERDTRVSLFSP-VHSRTYDMDVRLDLPP
VPDSADLSGL------AIKVPQSVDPSEDEGFQSASNLTPDSQSEHGTTPEIDPWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDAFNS-FCRLCRGELQVL-GGGL
PQAAQPVLVQECE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDVLNVL-IGVMSATFPLCQPTQAFMVKRGIHVSGTSPESISSLL
SEVAECGTHYARLSHFSLQPVLDASCSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGT-----CGGES-----RAPFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIYDWVYSGVFRDVYGEFMIQVNQDYLGFRDKSYWTH
GYVLISKEAGDCVPAFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAIY-VGRMERVARHSSISKEEKELRMEIAKQELIVQAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFMKDQERRRAARQEELDDDFSYARELRDRARRLQALE
EQLERKASMGRTASCSKLSAEAARREQKALWKVQRHRLASARAR-FLLEDQEHIQAMLRD
A-AEGRPPE---PPAVLPS-ACSQASSL----GPGH---------PDGGGSCDPGCA---
E-QHVAAWDGP---SR--PQPLEPPALGACSSSELGAGLQPGQAEGPGLFSAGLSIQDFL
PTGQG------------------AEQPGGAGVAPVLEEALQTIGSDLRSSA---SSAT--
-AGTGCSGPQEYDFRTVLRPALVTS-ASGSLQTVGGSLGCEGLQLWGDTHEFRLDTCVPD
GQV------------ALPHPCPPRNNLPKEGSSQTMGQLLGHVS----------EGGILT
---------------------------------------------GGNASGMAPSRPRWN
VHGHVSDASIKVGENVWDVAPSRPRWN---VHGHVSDASI-KVGENVWDVAPSRPRWNVH
GHVSDASIKVGENVWDVAPSRPRWNVHGHVSDASIK-----------------------V
GENVWDVASSRPRWNVHGHVSDASIKVGENVWDVAPSR-----PRWNVHGHVSQSQVMLG
DPPGETQPDKPRPL----------------------------------------------
-------------PSPPDHVSQPGLS----------------------LGAQSPTWDHDS
----QLLAEPASVSACTRVAGSG--EEGSLQALPGAEAGPSAVGDSTPE---PGQWSAEL
SCRWWCPG--PGGGGGRAGSLLSWDLGG----AAHSSTGPDSPSWPICRSGPGRSGDTE-
----------DGSASQPS---------SSQECAASLSSPGLEEEAED-----GAVARRQG
REQAYLAGLVEQYRLEQYPDSYEAMSEPPVARLLHHGLPRAFSLPEDTRGPLGTETVDET
AVQLSELLPLPVLMKHSVTAPLAAHVSLVNKAAVDYFFVELQLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNAVLRKALQYSLHGDSPLAANLSFALKFLPEA
FVPNAPDVLSCLELRYKVD-WPLNIVITESCLSRYSAIF-FLLQLKLMMWTLKDVCFHLK
RTA----LVSPAAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SVFSLVLKFRSQLISQPWGPAGGPHGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------VPRSVDQWEDEGFQSASNLTPESQSEPSVTPDVDLWEAALT
YEASKR------RCWERAG-CPP-GHGEEPYLTEAGRGAFDR-FCRLRQGELQLL-GGGA
LQAPQPLVVKECE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDALNVL-IGVVSATFSLCQA-QAFVVKQGIHVSXXXXXXXXXXX
XXXXXXXXXXXXXSRFSLQPVLGSPHSKGLVF-AFTSGLRRYLQYYRACVLSTLPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAALPGAGGAGP-----RPAFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLMKTSCEPYTQFIHDWVYSGVFRDVYGEFMIQVNPEYLGVRNKFYWTH
GYVLISREAEDCVPVFLRHTVHDVYVCGK-TVNLLKLCCPQHYLCWSDIPVPRISVIFSL
EELKEVEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIVHAREAASRVLNALSD
RQMSEQMALDARKREQFQRLKEQFMKDQERRLAARQEELEDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRVQRHRLQRERLR-FLQEDEERIQGMLKG
V-SKVHKPQE--SLPVLC--AHFQVVSP----GPEH---------PDGRCGCDSMR---T
-EQHSASFDCSGKVSVQLPQPPQGP-----AV-------EARQAEEVEPFTVGVSIGDFL
PMGLG------------------AGRSVQTNTVPLLEEALQTIRSNLPPGPSGPPGEATA
VACTQPPVLQEYDFRTILRPAVATFPGPEPLQAVEGSEGPQHGGVLSMKLNTLG-SDMQV
---------------ATPQAELLRPGTPEAEYSKSTQQLPGQT----------SGDSVPT
GDCSSGLA---PTW--PHGHV---SDANIRV--------------GENVSDVAPSRPRWS
THRHVSDASIRVGENVSDVIPSRPRWS---AHGHVSDASI-RVGENVSDVAPSRPRWSSH
GHVSDASIRVGENVSDVAPSRPRWSSHGHVSDASIR-----------------------V
GENVSDVAPSRPRWSSHGHVSDASIRVGENVLDVAPSP-----LQWSAHGHVSDSSVQAG
ENMSNVDPSLPGWSVHGHMLDCGVGWGE----HVPSRPRWSTHTSQS--YVVLGELSSKD
EPM-----VSRPQRRCPGDGFQSGLS----------------------LGTQRPLLECRL
----QPPVEVV-----PSICQSGSGSGEES------------------------------
----------------SLPTSPPT------WPGT---LGD----SASEEPGLGSSKDTE-
----------DLSPDRPL---------SLQEEAATQRSPGAAEA----------VAEGRH
AEQAYLAGLARQYHLEPYPDCYESMSEPPVAHLLHHVVPRAFAFPVDPQIQ---AAADET
AVQLSELLTLPVLMKRSITAPLAAHVSLVNKAIVDYFFVEMQLESHLEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLALNSILSKALQYSLHGDSPHAANLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLSQYGGIFSFLLQLKLMMWTLKDICFQLK
RTA----LLSHTAGSVQLRQLQLFKHEMQHFVKVIQGYVASQILHVSWCEFRARLAVVGD
LEEIQRAHADYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

------LFDDLCEALLPAAK--THLARS-V-NRRGKAEPQEVAYNALSQIFFKNKD----
------------PHVVFDLRVVAW-PKATVWRALWRRLKQP--LPGP-LLRGSVFGPPGH
SGGSGPLQVLPRKRDTSLTT-SMWEKRPYSGYDCDDLSV-EMDVQSLISRESWS--AMIQ
ETS-GYGGCSGTGLPTV--GLFSVGDPCGDRS-RETPGSRLRALVHSRTIMTGRPTGPAP
VPDNADSLAISGGLPFRVASPPSVDQWEDEGFQSS---------EPSVTPDPA-----LT
YEASKRMLDATCCCWNRG--CPPWPTEEEPYLRRREEPAFRQVLQRLRQGELQAACLGAV
LQAPQPCLCE---GVPNVLNVLDCGVVSATFSLLPRVRTA--------------------
---------------------------------------------------HRP------
----------------P-QWCGA-------------------------------------
------------------------LASWLT------------------------------
--CLSLRGVGLCSRCFCKHIAYDIYVWGERRINWLKLCCSPALLCWSRPSAV--------
----PAGSDCAAYGWGAMERVARHSCLSQ---ELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
V-SEAHQPQE--PPDVLLS-VHPQVTSP----GPEH---------PEGGQGCDSGS---A
-EQHSPAWDGRNRPGLLTPQPLKPL-----AV-GAGGT-GLQQAEEARPFSDSLSIGDFL
PVGPG------------------AEPSVQTGMVPLLEVALQTINLDLPPSA---PGEAPA
AASTQLSRPQEYDFSTVLRPAVATSPAPGPLQAAKCSLGSSGLQLWEDSCGKMD-ACGST
SRE------------TLLPSHPSRRAALEEGSSQPTERLFGQVS----------GGGLPT
GDFASEIAPARPRW-NTHGHV---SDASIRV--------------GENVSDVAPTRPRWN
THGHVSNASISIGESVSDVAPTRPRWN---IHGHVSNASI-RVGENVSDVAPTRPRWNTH
GHVSNASIRVGENVSDVAPTRPRWNTHGHVSDASIS-----------------------L
GESVSDVAPARPQWNTHGHVSDASISLGESVSDMAPTR-----PRWNTHGHVSDASIRFG
ENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVVSTRPRWNTHVPIPPPHMVLGAPSPEA
EPN-----TPRPQQSPPGHTSQSALS----------------------LGAQSTVLDCGP
----RLPVEVG-----PSLSSPSSGCGEGSI-----------------------------
---------SVGENVSDVAPTQPW------WPNT---PGD----SVSEELGPGRSGDTE-
----------DLSPNWPL---------NSQEDTAAQSSPGRGE-----------------
-EQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SA

PF04130 // ENSGT00850000132278_2_Domain_2 (1737, 2024)

ADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPRELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITEGCLSKYSGVFSFLLQLKLMMWALKDVCFHLK
RTA----LLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASVPQLVDDLCEALLPAAK--AHSGQRRGSRKKAKQSLKRVAYNVLFTSLFQDETRKLQ
PGLPRLPVKNRILMLSFDLRVSGLGAEADRLEELVEELEAAH--RRPLAELGSVLDLLVR
LVGSGPPRMLRRGGDVFLHSGRVGRDVPYGGYDCDWSGLEAXXXXXXXXXXXXXXXXXXX
XXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALVHSRTADLDVRLDLPP
VPDSADLSGL------AIKVSSSVDQSEDEGFQSASNLTPDSQSEPGMTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRAAFDR-SCRLCQAGLQVL-GGGL
LQAPQPVLVKECE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDALNIL-IGVVSATFSLCQPAQAFTVKQGVHVSGASPESISSLL
SEVAECGTHYARLSHFSLQPVLDSSCSEGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIAFLFKKLGRQLRYLA-ELCGVGTGLLGAGGRAP-----GAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEDCVPVFLRHVAHDVYVCGK-TINLLKLCCPRHYLCCSDVPVPRVSVIFSL
EELKDIEKDCAIY-VGRMERVARHSSISKEEKELRMEIAKQELIVQAREAASRVLSALSD
RQLSERMALDAQKREQFQRLKEQFVKDQERRRAARQEELDDDFSYARELRDRQRRLKALE
EQLERKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXX---XXXXXXX-XXXXASFL----GPEH---------PDGGGSCDPGHE---
GR-HEAARDSPDRQSVLTPQPLEPPAAGACGSG-------PEQAEGPGPFSVGLSIRDFL
PTAQG------------------AEQPVLTSAAPVLDEALQTIGSDLPPLA---PSAA--
-ADTGPSGPQEYDFRTILRPSVAAPASPGALQTAGGSLGSEGQRLREDTHV-QLDTCVPD
GRV------------ALPYAHPPQHPSCQEESSQDPGQLCGQVA----------EPGVPT
---------------------------------------------EGYASGMAPARPRWN
VHGHVSDANIRVGENVWDVAPSRPRWN---VHGHVSDASI-RVG----------------
------------------------------------------------------------
----------------------------ENVWDVAPSR-----PRWNVHGHVSQSSVMLG
LLSGEAEPNVPGPL----------------------------------------------
-------------G-APDHGSRSGLS----------------------LGAQSPAREDEP
----RLPAETASG-------GSGRGEETGLQDLLSAEAAPTALEDSIPE-----------
------------------------------------------------EPGPGASGDSQ-
----------DLSPGGPP---------SSQEGVDTRSSPGPGEEA-----------PALD
REQAYLAGLAGQYCLERYPDSYEAMSEPPVARLLHHGLPRAFALPEDPGAQ---SDADAS
AVQLSELLPLPVLMKHSITAPLAAHVSLVNKAAVDYFFVELHLGAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLVLNSVLSKALQYSLHGDTPHAANLSFALKFLPET
FAPNAPDVLSCLELRYKVD-WPLNIVVTEGCLSRYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----RVSHAAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFQARLASVGD
LKEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
STFSLVLKFRSQLIAQPW------RGPEHPNFALLQQSYSTFKYYSHFL-----------
---------------------------FKVVSKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

MASITQLFDDLCEALLPAAQ--ARPGQRSVNRKRAKLSLKRVAYNALFANLFQEETQQRQ
PDSSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEAIP--GCPFVEVECVLGLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNLPYSGYDCYDLSVFEMDVRSLISGEEYLCHNMVQ
EALQVMESAPGTGLPTV--GLYSIGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWETVLT
YEASKR------RCWERIG-CLP-GHREEPYLTEAGRDAFDR-FCRLCHGELRAL-SGGL
LQGPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSFCQPTQAFVVELGVHVSGASPESISSIL
SEVAEYGTYYTRLSHFSLQPVIGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVSLAT-SGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERLARHSSISKEEKELRMEIAKQELIVHAREAASRVLRELSD
RQMSEQMAVDTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLQ-FLLEDQKRIQEMLRD
M--EAHQPQE--PPSMFPS-TCSQVTSP----CPEH---------ADEGRSCDLGS----
---TELQWNC--PSGTSTPSVLKSA-----AE-GADDS-GTGQAEGAGPFSSGLSITDFL
PTGPG------------------AEQPVDNTGAPFLEAALQTICSDLPPIT----GPT-L
TAADPQPTQSEYDFNTILRPALAASSSPGPFQDVQNGLDSETQYVLGDMPTKLN-ACVHD
VQ------------ETLPCPHPLKHVTPEEGSFQPVGQFLEHMS----------GTVIPT
ESLASGMAPCQQLR-SISRCV---SDANTKG--------------EDYMSDMALPRPQWN
ICGPVSEASIGVGENVSEVASSRPRWN---VHGHVSDASI-KVGENVSDVAPSRPRWNIH
GHVSDASIKIGENVSDVAPPRPRWNVHGHVSEGSIK-----------------------I
GENVSDVAPSRPRWNIHGHVSDASIKIGENVSDVAPSR-----PRWNIHGHVSDASIKVG
ENVSDVAPPRPRWNVHGHVSEASIRIGENVSE--EAP--QPHGCT-QP-PLILEEPLPEA
EPD-----LLKPRQCSPAHVSQSGLG----------------------VEAQSPTLECGP
----QLPGETK-----PTICSS-PGSIEEGSL----------------------------
----------------ETMPP---------VVAEPSILGN----GILEETGPERSRDAE-
----------DLSPWPP----------SSQEDTAVPSSPGPSEEVSDTEA----EARRWG
KEQAYLADLTQLYHLEQYPDSYESMSEPPVAHLVHHMLPQAFAFPVDPQVQ---SAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVTLVNKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHATNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTGGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVSD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQTWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------PP-GHREEPYLTEAGREAFDS-FCRLCEAGLQVL-GGSL
LPPQQRVLLHEGE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 2089)

LVQDTLNVL-IGVASTTFSLCQPAQAFMVKPGVYVSGTSPESMHSLL
SEVAACGTYYMRLSHFSLQPVQDAVGSKGLVFQAFTSGMRRYLQYYRACVLSTPPSLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTGLPGTNSGGP-----RAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLQTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNEDYLGCRDKSYWTH
GYVLIAQEAEDCVPVFLKHVANDVYVCGK-TVNLLKRCCPRHYLCWSDIPVPRISVVFSL
EELKETEKECAVY-MGRMESVARYSSISKEEKELRAEIAKQELIVHAREAASRVLSALSE
RQMAERAALSAQKREQFRRLKEQFVRDQERRLAARQEEAEDDFSYARELRDRESQLQALE
EELERRARQALVEHYRRLSAEAACREQKALWKLQRHKLSEARST-FLLADQARLQLGAVA
GGHQVCRPVL--PWPVE----------------------------PTGGDPHRSGQ---A
----LAEPTPAEGRGLLTPLPLS------------------SSVSESEPFSAGLTIQDFL
PPGEAPLLG------------------ELWMGAPLLEQALQTIGADLPSMVGVPPAA---
---CTQHPRQEYDFSTVWGLVGLP--------SLQATEGSPDPQLQWNTPPKKD-ACSSD
MLLAQ----------PPPPSQPPRS-ASE-------------------------------
-------------ENPFHGHV---SDSSIRV--------------GENVSDVAPSRPRWN
VHGHVSDASIRVGENVSDVAPSRPRWN---VHGHVSDASI-RVGENVSDVAPSRPRWNVH
GHVSDASIRVGENVSDVAPSRPRWNVHGHVSDASIK-----------------------V
GENVSDVAPSRPRWNVHGHVSNASIKVGENVSDVAPSR-----PRWSIHGHVSDASIKVG
ENISDVAPSRPRWSIHGHVSDASIKVGENISDVAPSRPRSGHAPQFHT---TLEVLSEEA
ESE----------------ESGPCLS---------------------------PSLEHES
----QLPAETRA-----LEPVPSAGGREESS-----------------------------
L--------------------------QAGASARPDALGD----GVSGELGPSSGDSAG-
-------------PSPPV---------KSQAGEIVQGSPESGED----------------
RGQDALETLAARYHLEQYPDSEAMXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTWCEFRNKLASVGT
LEEAQRAHAEYLNKAIF--------------------------R-GLLTEKAAPVMNLIH
STFSLVLKFRSQLISQAWDA------AEHPNFTLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRGVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKIVMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLPRNRDYFLNNKHVGRNVPYSGYDCDHLSVFETDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDSCGDRFERDTRVSLFGALVHSRTDDMDVRLGLPP
VPDSADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_1 (377, 562)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPY

ENSGT00850000132278_2_Linker_1_0 (562, 624)

T--------------------------------------
----------------------D

PF04130 // ENSGT00850000132278_2_Domain_0 (624, 2024)

VYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
M-SEAHQPQE--PPDVLVS-VHPQVSSP----GPED---------PEGDQGCDAGP---A
-EQHSAAWDGRNRPGLPTPQSLKPL-----AM-GAGGT-GLQQAEEAGPFSDSLSIGDFL
PVGPG------------------AEQSLQTGVVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAVAASPAPGPLQAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRAALKEGSSQPAEQLFGHES----------GGGLPT
GGYASETALTRPQW-NIHGHV---SDASIGV--------------GENVSEVAPTRPRWN
IHGHVSDASI-------------------------------SLGESVSEVAPTRPRWNTH
GHVSDANIRVGENMSDVAPTWPRWNTHGHVSDASII-----------------------L
GEPVWDVVPTRPRWNTHRHVSDA-------------------------------------
----------------------SISLGKPVSDVVSTRPRWNTHAPVPLPHMMLGAVSPEA
EPNT-----PRPQQSPAGHTSQSALS----------------------LGAQSTVLDCGS
----RLPVEVG-----PSLSSLSSGCGEESI-----------------------------
---------SIGENVSDVAPTQPW------SPNT---PGD----GVSEELGPGRSGDTE-
---------------EPL---------NSQENAAAQSSPGPGEEA-------AVAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

MASITQLFDDLCEALLPAAK--PHLGQRSVSRKRAKQYLRRLAYNTLFTNLFQDETNKLQ
PDHSKLPVKNKILMLSFDLRVGGLGPEADRVEELVEELGTPP--SCPFAEVGSVLDLLVQ
LAGSGPPQVLRRSRDYFVNHRHLGRNVPHSGYDCHYLSVFERDVQSRICREEYVCQDMIQ
RTLQMMEAAPGTGLSSF--GLFSYGDPCVDRFERD-RVSLFGALVHRT---DDVRLDLPX
XXXXXXXXXX------XXXVPHSIDQSEDEGFQSASNLTPDFQSEQGLTPDIDLWDAVLT
YKASKR------RCWEQIG-CPP-GHREEPYLTEAGRDAFDR-LCRLHQGELQLL-GGSL
LQAPLPILVKESE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDALNVL-IGVVSATFSLCQXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAFTSGLRKYLQYYRACVLSTPPTLSLL
TINF-FNKVGRPLLYLA-ELCGVGITPWGTSGGEP-----GTEFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDNYGEFMIQVNHEYLGFRGQSYWTH
GYVLISKEV-DCVPVFE-HIAHDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXELRMEIAKQELIVHAREAASRVLSELSD
RQMSERMAVDARKREQFQRLKEQFVKDQERRRAVRQEELDDDFSYARELRDREQRLRALE
EQLEKKARQVLVDHYSKLSAEAARREQKALWKIQRHRLASARMR-FLLEDQKHIQAMLKD
M-SEGRPP-E--LPVVLPG-TCFQASSP----GSELLDAVGSSSSS------------EH
AELCRATGDCSHRPGSPSXXXXXXX-----XX-XXXXX-XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXRPRWN
IHGHVSDSSIKVGENVWDVATSRPRWN---IHGHVSDSSI-KVGENVWDVATSRPRWNIH
GHVSDSSIKVGENVWDVATSRPRWNIHGHVSDSSIK-----------------------V
GENVWDVATSRPRWNIHGHVSDSSIKVGENVWDVATSR-----PPWNIHEHVSQPHMRPG
LLCGE-------------------------------------------------------
----VELDVPRPHSSPPDCMHQPDLS---------------------P-VAQSPAQELEP
----EPPADLG-----QLLCSGG----------------------------MLRGWEEGH
FGLNS-------------------------DAARPDDLGE----DICKEPGPGTTGDIE-
----------DLSPSRPP---------NSQEDTASQSSPGSGKQQE------GEMDSAQC
REQAYLAGLVGQYRLEQYPDSYEAMSKPPVARLLHHGLPRAFALPEEPREL---SDTDET
AVQLSELLPLPVLMKHSLTAPLAAHVSLVNKAAVDYFFVELRLEAHLEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLTPLVLNSLLSKALQYSLHGDMPHAANLSFALKFLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLSRYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----LVSQAAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVSD
LEEVQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQPWAPARGPRGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASITQLFDDLCEALLPAAQ--ARPGQRSVNRKRAKLSLKRVAYNALFANLFQEETHQRQ
PDSSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEASP--GCPLVEVESVLDLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNVPYSGYDCYDLSVFEMDVRSLISGEEYLCHNMVQ
EAVQVMEAAPGTGLPTV--GLFSAGDSCGDRFERDTRVSLFGALVHSRTCDMDVRLDLPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLT
YEASKR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-FCRLCHGELQAL-SGGL
LQAPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQPTQAFVVELGVHVSGASPESISSIL
SEVAEYGTYYTRLSHFSLQPVVGSSCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSLAT-SGEP-----RPVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSISKEEKELRMEIAKQELIVHAREAASRVLRELSD
RQMSEQMAVDTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDQKSIQEMLRD
M--EAHPPQE--PLSVFPS-TCPQVPSP----GPEH---------ADEGHSCDLGS----
---AELRWDHPSPPSASTPSALQSA-----AE-GVDDP-G-----GAGPFSPGLSITDFL
PVGPG------------------AEQPVDNTGAPFLEVALQTISSDLSPVT---PGPA-L
TAADPQPIQSEYDFNTILRPAVATSSSPGPSQDVQNGLDSEKQHLL-DMPTKLD-ACVHD
MQ------------ETLPCPHPLKHVTSEEGTFQPVGQLLEHIS----------GTAVSA
ESLASGMAPCQPL--SISGCV---SDASIKQ--------------GDYMSDVALPQPQWN
IHGHLSHASTGAGENVSEVAPSRPRWN---VHGHVSEASI-RIGENVSDVAPSRPRWNVH
GHVSEANIRIGENVSDVAPSRPRWNVHGHVSEASIK-----------------------I
GEN--------------------------NVSDVTPSR-----PRWNVHGHVSEASIRIG
ENVSDVTPSRPRWNVHGHVSDASIRIGDSVSE--EAL--QPHGCP-QP-PLILEEPLPEA
EPD-----LLTPQQCPPACVSPSGLH----------------------VEAQSPVGESGP
----QLPGETK-----PTLCSS-LGSTEEGSP----------------------------
----------------QTKPP---------VVAEPSTLGN----GIPEETGPGRRRDAE-
----------DLSPWPP----------SSQEDTAVPSSPGPSEEVSDTEA----EARRWG
KEQAYLADLTKLYHLEQYPDSYESMSEPPVAHLVHHMLPQAFAFPVDPQVQ---SAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVSLVNKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHAANLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQSWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRQRAKQSLKKVAYNALFTNLFQDEMRQLQ
SDLSKLPVRNKILMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPLVEVGSILDLLVQ
LAGSGPPQVVQRKRGYFLNNKRVGRNVPYGGYDCYDVSAFELDIQSLISREESLCLSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCSDKFERDTRVSLFGALVHSRTYDLDVRLDLPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEPSKR------RCWERVG-CLP-GHREEPYLTEAGRDTFDR-FCRLRQGELQVL-SGGL
LQAPHPVLVKECEL

PF04130 // ENSGT00850000132278_2_Domain_0 (375, 2024)

VKDALNVL-IGVVSTTFSLCQLAQAFTVKCGVHVSGASPESISSLL
SEVAEYGTYYTRLSHFSLQPVLDASYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGIALPGASGGGP-----RAAFPTGVKLLSYLYQEALG
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGCRDKLYWTH
GYVLISKDVEDCVPVFLKHIAYDVYVCGK-TINLLRLCHPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMARVARHSSISKEEKELRMEIAKQELIVHAREAASRVLSELSD
RQMLEQMALDARKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDRERRLRSLK
EELERKA--------SKLSAEAARREQRALWRVQRHRLESARLR-FLSEDQRCIQGVLED
V-LEGHRPQEPLPLAVLQS-ACSQATSL----GPEH---------PDRGQGCDSRP----
RKRHLGTWDCVHRLSAPVSPSLEATAMGTCE------GLQPG--DKAGPFSAGLSVGDFL
PMRLE------------------AEQPVQTSEAPLLEEVLQTICPDLPSAA---LGETPA
AASTQSCELQEYDFSTILRPAVAT--SPGTFQAIEGSLSSSGQQMWGDTGMKLG-ACVPD
TQV------------ALPQSYPHSSVTSEEGSSHSTEQPLGHMS----------GNDVPT
---------------------------------------------EGCVHGMAPSRPQWK
LHRHVSDASIRVGENVSDVAPSRLRWN---LHGHVSDASI-RVGENVSDVAPSRPRWNLH
GHVSDASIRVGENVSDVAPSRPRWNLHGHVSDASIR-----------------------V
GENVSDVAPSRPRWNLHGHVSDASIRVGENVSDMAPTR-----PWWNTRGHISQFPMMLG
TLSSEAEPNKSGTP----------------------------------------------
-------------QASAGQVSLAGLS----------------------PGAQSLALESGP
----QSPVETVLSAYSSA--SGSEEESSL----------------------------QTS
PSAVARPH--TL-------------------GDGVH-----------EEPGPGRSGDTE-
----------DLSASWPL---------NPQEDAAAQSSPGSGKEAV--------EARRWG
QEQTYLKGLATQYPLERYPDSYEAMSEPPAAHLLHHALPRAFAFPVDPEVQ---SAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHCEALRHFLLMEDGE
FGQSLSDLLFEKLGAGLTPGELLSPLALNSVLSKALQFSLHGDSPHAANLSFALKYLPEA
FAPNAPDVLSCLELRYKVD-WPLNMVITESCLSKYSGIFSFLLQLKLMMWTLKDVCFHLK
RSA----LVSRVASSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVTWCEFRARLAEVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLIAQAWGPASGPQGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

------------------------------------------------------------
-------------MLSFDLRVGGLGAEADRLEELVEGLEAAP--RQPLAELGAVLELLVR
LAGSGPPRVRRRRRGVFLHSRPVGRALPYGGYDCADLSELEADVRSLISGEESLCRDLVR
KTRQVMEAAPGTGLPAV--GLFSYGDPCGDRFERDTRVSLFGALVHSRTADLDVRLDLPP
VPDSADLSGL------AIKVPPSVDQSEDEGFQSASNLTPDSQSEPGVTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQGELQVL-GGSL
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DALNVL-IGVVSATFSLCQPAQTFTVKRGVHVSGASPESISSLL
SEVAECGTHYARLSHFSLQPALDPSCSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGATLQGSGGGEP-----RAAFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGFRDRFYWTH
GYVLISKEAEDCVPMFLSHIAHDVYVCGK-TINLLKLCCPQHYLCCSDVPVPRISVVFSL
EELKGIEKDCAAY-VGRMERVARHSSVSKEEKELRMEIAKQELIVQAREAASRVLQALSD
RQMSERMVSDARKREQFQRLKEQFVKDQERRRAARQEELDEDFSYARELRDRERRLRALE
EQLERKARQALVDHYSKLSAEAARREQRALWKVRRHRLASARLR-FLLEDEKRTQGMLEA
V--AEGRPLE--QPAALPG-ACSQTSAHS--WAGDQASFLGP-VPRDRGGSCDPGREE--
--PREAAPAGPHGQSVLTLQPLESPGAEAYRA-GPGAGLLWGQAEEPGPFSMGLSLRDFL
PAAQGAEPG------------------L-GRAAPILEEALQTIGSDLPPMAPSTAG----
--DLVPVGPQEYDFRTILRPAVAAPGSTGALQTAGGSPGSRGQQPQEDTQVPLS-TCGPD
PPQR---------------------PSPQEERCPATAQVLG-------------------
--------------------------------------AEPGVPRGVCASGMTPSRPRWN
------------------------------VHGHV-------------------------
------------------------------SQSSVMLGVLSGEAEPNLS-----------
------------------------------------------------------------
------------------------------------------------------------
----------RPPLGPPDPGPQLGLS----------------------SGTQGLAQEHMP
----RLPAETASGSSSAQVAGPGPGHGEEGG-----------------------------
PQASLS------------------------AEAVPAALGD----STPEEPGLGMSEDSRD
L---------------SP---------GSQEDADVQSSPDPGEA----------AAQLWD
REQAYLAGLAGHYRLEQYPDSYDAMSEPPVARLLHHGLPRAFALPEDARVP---SDADES
AVQLSELLPLPVLMKHSVTAPLAAHVSLVNKAVVDYFFVELNLGAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLVLNSVLSKALQYSLHGDSPHAANLSFALKFLPET
FAPNAPDVLSCLELRYKVD-WPLNIVVTEGCLSRYGGIFSFLLQLKLMMWTLKDVCFHLK
RTAR----VSQAAGSAQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFQARLASVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SVFSLVLKFRSQLISQPWGPAGGPRGPEHPNFALMQQSYSAFNGEQAGEPRLPAP---PG
GLPAAHQLQQLLPGRLSPGSAAINVYPPSSLCLRGGRGRSNHAG-PL--RRLPVYWGAAP
PSTPARSCQLSLPHTAALDSRWAPNLMG

MASITQLFNELCEAHLGHVRWKAHRGRQGASVRRAKQGLKRVVYDALFVDLFQDEGHKPP
SAGSQLPVKNKILMLSFNLRVGGLGPDADRLEELVEGLEAAPALGLPLADIRAVLDLLVH
LAGSGPPL-LPPKRDYFLNNKHVGRNVKHQGYDYYDVSMFEADARFLIASQEQQCRDVIQ
KTLQVMEAAPGTGLPSI--GLFAQNYPGVDRFERETHGSLFGALVHSRTYDMDIKLDLPP
VPDNADLSGI------AIQVPQSIDQSEDEGFQSASNLTPDSQSEPSMTPDIDLWDAALN
YEPNKR------RCWERIG-CPP-GNKEEPYLTEAGREAFDM-FYRLREGELQLL-HSSL
LQLPPLFLMKEREL

PF04130 // ENSGT00850000132278_2_Domain_0 (375, 2024)

VKDVLNVL-IGVVSATFSLSQASQAFEVKQGVYVSGTSPQNMSSLL
SEVAEYGTHYTRLSRFSLQPVLDSSYSKGLVFQAFTSGLRKYLQYYRACVLSTPPTLSLL
TISFLFKKLGRQLRYLA-ELCGVGAAVPGLSEGGT-----KSSFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKASCEPYTRFIHDWVYSGVFRDVYGEFMIQVNEEYLSCRDKFYWTH
GYVLISKEVEDCVPVFLKHVANDVYVCGK-TINLLKLCCPQHYICWSDIPVPRISVIFSL
EELKEIEKDCAVY-VGRMERLARHSAVSKEEKKLRMEIAKQELIVHARDTASRVLKALND
RHVSERMALDAKKREQFQKLKEQFLKDQERRLAAKQEELDDDFSYARELREREKRLKALE
EELERKA--------SKLSEEAARREQRALWKIRRHKLETARLN-FFKEDQKRIQVASAR
T-PEGSH-----IVTNVPV--HDELSLC----SGYR---------PWGGCWGNGLW---A
PGGSTTEYERLSKPVVYSEQRTKDW-----KR-ALGKP-TH----ARKHRSVAVLYSEFQ
EMLQNVSEGKYREKLDILPGVRPPGHVDASAGEPGVQ----SSEAPLVPWD---GELS--
------------PFPSWIRDPSSSSLLPSPPHTSVCPP----CADWRSICGA----DSQC
RGLRSLLSG------MTGPQYLLS-------------------GSCSPLPHCRGTASFTG
IGKLSFVSSQSPTLPCSHHQA---GQCSENI--------------GERAQGLPPSVGTWT
AEQMDPEKEGPEKAGPEDVGPEKDGLEKMGPDGHTLEPKLPGSGLDMDDFLPRPLPEQLP
A-ASGSPALLEA---------ALQTISADLPPAHLK-----------------------L
GDLTLEAEDPRPQGSTFGHVSKSSLQLGQRELPPSPKP----LPRQTVPAAAT-------
---STMQWFLYNRE-LGC--------------------------PVP-----DQPPQAG-
--E-----APRTSAAA-AEAGEPGTQ---------------------HLFTSPDTVAFGP
LRKPWVDASPG------AWFPPPGGCCPDQPPLSSAYEGLAWFAHEAPRAKLGVGWGTRG
TEATLRPQSSLGGLLGARGSPLPS------QGQVC--SEV----GFSHSQDPGIGGHREE
NSDVMSDESGDVSPNQPP---------EPQKEAEAPTMAASPEE-----A--KDGAKGCA
REQAYLKALSDQYCLEKYQDSYGLMSEPPVSHLLRHIIPRPFSFPMDPRGP---TATDET
SVQLSELLTLPVLMKHSITAPLVSHVSLVNKAVVDYFFVELSLEKHFEALRHFLLMEDGE
FAQSLSDLLFEKLGSGQTPGEFLNPLVLNSFLTKALQYSLHGDTKLAANLSFALKYLPEV
FTANAPDALSCLELRYKVD-WPLNIVITESCLNKYNKIFSFLLQLKHMMWTLKDVCFHLK
RTA----LVNHASGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWREFGNKLSSVSN
LEEIHRTHAEYLNKAIF--------------------------R-GLLTEKAAPVMNVIH
SIFSLILKFRTQLISQAWTYDGGQQVAVHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYRDT-
----------------------------

MASITQLFDDLCEALLPVPK--ARLGQRGVSRRRAKQGLRRVAYDALFSSLFVDETQRLQ
PDPSKLPVKNKILMLSFDLRVGCLGPEADRLEELVEELEAAP--CCPLVEVGSVLDLLVQ
LAGSGPPRVLPRKRDYLFNNKHVGRNVRYGGYDCYDLSVFEMDVQSLISREEYLCQDMIH
KALQVMEAAPGTGLPTV--GLFSYGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADLSGL------AIKVPQSVDQSEDEGFQSASNLTPDSQSEPGVTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDAFDR-FCRLHQGELQVL-GGGL
LQAPQPVLVKECEL

PF04130 // ENSGT00850000132278_2_Domain_1 (375, 718)

VKDALNVL-IGVVSATFSLCQPAHAFMVKRGVHVSGASPESISSLL
SEVAECGTHYARLSHFSVQPVLDSSCSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTALPASSGGEP-----GAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNQEYLGFRDKFYWTH
GYVLISKEVEDCVPMFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAIY-VGRMERVARHSSISKEEKELRMEIAKQELIVHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRRAARQEELDDDFSYARELRDREKRLKALE
EQLERKARQALVDHYSKLSAEAARREQKALWRIQRHRLAGARLR-FLLEDQKRIQVSLFQ
A-GALPLRNWKD----QCV-LVFQASSP----GPEH---------PDGGSSCDSGS----
AEQHVVAWDGLSRPSAPLQPLESPA-AGACSS-GPGAGQQPGQAEGPGPFSASLSIQDFL
PLGQG------------------AKKPVHTGMAPVLEEALQTIGSDLPPLG---LSAV--
-VGTGLAGPQEYDFRSILRPAAATLASPGPLDTVGGDLGSEGQQLWGDTHMQLD-TCVLD
GQM------------ALLDPHSPQHNSLQERSSQATGQVLGHVS----------ESSVPT
---------------------------------------------GGYASRIAPSRPQWN
IHGHVSDASIRVGENVWDMTPSRPRWN---VHGHVSDASI-RVGENVWD-----------
------------------------------------------------------------
------VVPSRPRWNVHGHVSDASVRVGENVWDVAPSR-----PRWNVHGHVSQSHMMLG
ALPEEAQIDVPRSH----------------------------------------------
-------------QNSPDHVSQS-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

MASITQLFDDLCEALLPAAQ--VRPGQRSLNRKRAKQGLKRVAYNALFTNLFQEDTHQRQ
PEPSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEELEAAP--TCPLAEVGTVLDLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNVPYSGYDCYDLSVFEMDVQSLISGEEYLCHNVIQ
EALQVMEAAPGTGLPTV--GLFSVGDSCGDRFERDTQVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQSMDQWEDEGFQSASNLTPDSQSEPSMTPDVDLWETALT
YEASKR------RCWELIG-CPP-GHREEPYLTEAGRDAFNW-FCRLHRGELQTL-SGGL
LQPPKPVLVTESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQPAQAFVVERGVHVSGASPESISSIL
SEVAEYGTYYTRLSRFSLQPALGSLCSRGLVFQAFTSGLRRYLEYYRACVLSTPTTLSLL
TIGFLFKKLGRQLRYLA-ELCGIGTALPGTSGREP-----RAKFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTQFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYICGK-TINLLKLCCPQHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERFARHSFVSKEEKELRMEIAKQELIVHAREAASRGLSELSD
RQMSEQMAMDARKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRVQRHRLESARLR-FLLEDEQRVQGMLRE
M-SETCQPQE--SQSVLPS-KCSKVTSL----SPEH---------TDASCSCDLGS----
---VEQLWGCPSLPGEPMPQLFQSK-----AE-VPGGS-GAGQAD-VEPFSEGVNITDFL
PMGPG------------------AKQPVKSSGTPFLEVALQTICSDLPPLT---PVVALT
----TVGTQPEYDFNTILRPIVTTSSSSGPLQDFDGSLGNEEQQHLWDVHTQLQ-AHLPD
MP------------TGLPHSHSLGHVTPEEGSYQLSEQFLENMS----------GTATPT
ESHVPGMVSCQPSW-CISGQV---SDAGIKV--------------QKNVSDVAPSQPQWN
VHGHISDASIRVGENVSDVAPSRPRWN---IHGHVSDASI-KIGENVSNVAPFQPRWNIH
GHISDASIKVGENVSDVAPSRPRWNIHGHV------------------------------
--------------------SDASIMIGENVSDVAPSR-----PRWNVHGHVSDASIKIG
ENVSDLAPSRPRWNIHRHVSDASIRTGECVSEVTPQSQCSIHGDTSQS-PKILGMLLPEA
GPD-----LSKPHWSSTGHMSQSSLS----------------------LELESPALEHEP
----QLPAELEP----PAICSSSPGSAEEGSP----------------------------
----------------QTNPA---------TVAEPSILGN----GIPQKKGPGRSGDTE-
----------DLSPSWPV---------SSQEGTATSSSPGPSEEVADTTD-SEAEAQRWG
KEQAYLAGLTRLYHVEQYPDSYESMSELPVAHLVHHLLPRVFAFPVDPQVQ---SAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVSLVNKAAVDYFFVELHLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPQATNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLSKYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFQARLAMVGD
LEEIQRVHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVSKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------DQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEVSKR------RCWERIG-CTP-GHREEPYLTEAGRDAFDR-FCRLRQEELQVL-SGSL
LQAPRPMMVTEQELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVASATFSLCQSTQAFVVAQGVHVSGASPESISSIL
SEVAAYGTCYTRLSHFSLQPALGASCGRGLVFQAFTSGLRRYLQYYGACVLATPSTLSLL
TIGFLFKKLGRQLRYLA-ELCGIGAILPGAGGGEP-----KASFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNDEYLGCRDKSYWTH
GYVLISKDVEDCVPVFLRHVAHDVYVCGK-TINLLKLCCPQHYLCWSDIPVPRISVIFSL
EELKEVEKDCAVY-VGRMERVAHHSCISKEEKELRMEIAKQELIAHAREAASRVLRELSD
RQTSEQMALDARKREQFQQLKEQFVKDQERRLAARQEELDEDFSYARELRDREKRLQALE
EELEKKARQALVDHYSKLSAEAARREQKALWRVQRHRLESARLR-FLLEEEKCLQEMLRD
L-SEVRHPLE--PPGVLPL-ACSEVRDL--SGSLEH---------SDGGQTCDLGF----
---PEQPGDCRGGLNVLAPQPLQSP------------------AAGAGPFSAGLSIVDFL
PTDSR------------------AEQPEQD-GTPLLDQALQTICSDLLPSS---TTEAPS
AEETLPAQPQEYDFSTILRPAVTAALSLGPLQ-AV--RDSEEQQLCVNTRGRPD-ECGPD
IHRPL----------CLPHPLTHRHGTAQEANSQIPGGFLAPTL----------GAAAPT
------------------------------------------EGRATE------------
------------------TAASQPGWN---IHGHVSDSSI-QIGENVSDVAASRPRWNIH
GHVSDASIRVGENMSDVATSRPRWNIHGHVSDSSIQ-----------------------I
GKNVSDVAASRPRWNIHGHVSDASIRVGENMSDVATSR-----PRWNIHGHVSDASIQIG
ENVSAVASSQPSWGGHTT---------------------------QPF--------FLEA
-----KSNPPRLPCSLPGQGSWPGTP-----------------------KVESSALECGP
----SISAEVD-----PATHCPGAGS-----------------------------WEDSS
LQASSC------------------------AIAEPGTVGD----SVSEQPGPGRNGDTE-
----------DLSACQPG---------DS-QDTATPGQPSPGEGEVEVDAEAEAEARRWG
EEQAYLASLARLYPLEQYPDSYEAMSEPPITHLVHHVLPWAFTFPMGLQAQ---PAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVSLVNKAAVDFFFVELHLESHFEALRHFVLMEDGE
FAQSLSDLLFEKLAAGQTPGELLSPLALNGILSKALQCSLHGDSPHAAGLSFALKHLPEV
FAPNTPDVLSCLELRYKVD-WPLNIVITESCLSKYSAIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHSAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWAPASGPLGTEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------PP-GHREEPYLTEAGRDAFDR-FCRLRQGALQVL-SGGL
PHAPSPVQVEEPE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDVLNIL-IGVVSATFSLCQXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXXXXXXX--XXXXXXX-XXXXXXXX-XXXXXXXX--------XXXXXXXXXXX---X
-XXXXXXXXXXXXXXXXXXXXXXXX-----XX-XXXXX-XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XX-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXSDASIRL--------------EENVSDVATDRPRWS
VHGHVSDASIRVGENVSDVAPARPRWS---VHGHVSDASI-RVGENISDVAPARPRWSVH
GHVSDASIRVGENVSDVAPARPRWSVHGHVSDASIR-----------------------L
GENVSDVAPARPRWNVHGHVSDASIRVGENVSDVAPAR-----PRWNVHGHVSDASIRLG
EDVSDVAPTRPQWSVHGQPPQLHLMLGG---------------------------PSPET
KAS-------TPSPSPPAL--QSDLS---------------------------LWAACE-
----------GA----LPLSAPGPGSGESTSG----------------------------
----------------------------------------DAPQWTSEAPGPRR-GDTE-
----------DTSPPLPL---------NSQESSAAQSSPGGEAE-------AEAEARRRD
WEQAYLAGLASQYHPEHYPDNYEAMSEAPAAHLIRQLRPRASAFPVDPQVQ---SATDEA
AVQLSELLTLPVLMIRSPAALLLVKISVGKKSLFDYFFVEL-LEPHLSLLWTFVLVEHAQ
LPQSLSDMLFEKLGAGQSPGELLSPLFLHTVLSKALQCSLHGDSPLAANLSFALKHLPEA
FAPNAPDVLSCLELRYKVD-WPLNIVITDGCLSRYGAIFSFLLQLKLMMWTLKDICFHLK
RTA----LLSHTAHSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVTWCEFRARLATVGD
LEEIQRTHAEYLH-AVF--------------------------R-SLLTEKTAHDMNIIY
SEISVCSIFRSQVISEPWGPAGGPRGSEHPNFALMQQSYHAFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNHYYQDA-
----------------------------

MASITQLFDDLCEALLPAAQ--ARPGQRSVNRKRAKRSLKRVAYNALFANLFQEDTHQRQ
PDSSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEAAP--DCPFVEVASVLDLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNIPYSGYDCYDLSVFEMDVRSFISGEENLCHHTVQ
EALQVMEAAPGTGLPTV--GLFSIGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLT
YEASKR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-FCRLRHGELQAL-SGGL
LQAPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCRPTQAFVVEPGVHVSGASPESISSIL
SEVAEYGTCYTRLSHFSLQPVVGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSLAT-SGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSCISKEEKELRMEIAKQELIVHAREAASRVLSELSD
RQMAEQIALDTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDQKCIQEMLRD
M--EAQQPQE--LPSVFPS-TGSQVTSP----GPEH---------AGEGHSCDPGS----
---TELHWDCSSLPCASTPSVPKSA-----AE-GADDS-G------AGPFSTGLSITDFL
PMDSE------------------EEQPMENSGAPFLEVALQTICSDLSPVT---PGPAAL
TAGGPQPTQSEYDFNTILRPAMATSLSPGPFQDVQNSVDSDKQHLLGDVPTKVD-SCIHD
IQ------------ETLPCPHPLSHATPVEGSLQPVDQLLEHMS----------ETTVST
ESHASGMAPCQQL--SISRHV---SDANIKV--------------GDYMSDVALPRPRWN
VHGHVSEASIGVGENMAEVAPSRPRWN---VHGHVSEASI-KIGENVSDVAPSRPRWNIH
GHVSDASIKVGENVSDVTPSRPRWNVHGHVSDASIK-----------------------V
GE---------------------------NVSDVTPSR-----PRWNVHGHVSDASIKVG
ENVSDVTPARPRWNVHGHVSEASIRIGENVSD--MDL--QQRGCA-QP-PLILEEPLPEA
EAD-----L-KPHQCPPAHVSEAVLG----------------------VEAQSPALECGP
----QLPEETK-----PTVCSG-SGRTEEGSL----------------------------
----------------QTE-T---------LVAEPSMLES----GIPEEKGPGRSRDAE-
----------DLSPCLPS---------SSQEDTAVPSSPGPSDEVSNTEA----EARRWG
KEQAYLTDLTKLYHLEQYPDSYDSMSEPPVAHLVHHMLPRAFAFPVDPQVQ---SAIDES
AVQLSELLTLPVLMKRSLMAPLAAHVSLVSKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHASNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQNWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLPRNRDYFLNNKHVGRNVPYSGYDCDHLSVFETDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAPQPVLVKECEL

PF04130 // ENSGT00850000132278_2_Domain_0 (375, 2024)

VKDVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVLGASPESVSSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPQHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHNSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKRIQEMLKA
M-SEAHQPQE--PPDVLLS-VHPEVASP----GPED---------PEGDQGCDAGP---A
-EQHSAAWDGRNRPGLPTPQSLKPL-----AT-GAGGT-GLQQAEQAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFNTVLRPAVAASPAPGPLQAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRAALKEGSSQPTEQLFGHES----------GGGLPT
GGYASETALTRPQW-NIHGHV---SDASIGV--------------GENVSEVAPTRPRWN
THGHVSDASISLGESVSEVAPTRPRWN---THGHVSDASI-RVGENVSEVAPTRPRWNTH
GHVSDASIRVGENVSEVAPTRPRWNTHRHVSDASIS-----------------------L
GEPVLDVAPTRPRWNTHRHVSDASISLGEPVLDVAPTR-----PRWNTHRHVSDAGISLG
EPVLDVAPTRPRWNTHGHVSDASISLGEPVWDVAPTRPRWNTHAPVPPPHMMLGAVSPEA
EPNT-----PRPQQSPAGHTSQSALS----------------------LGAQSTVLDCGS
----RLPVEVA-----PSLSSPSSGC----V-----------------------------
---------SIGENVSDVAPTRPG------SPKT---PGD----GVSEELGPGRSGDTE-
---------------EPL---------NSQENAAAQSSPGPGEEA-------AVAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------ASGETPA
AASTQPSPRQEPDLSTALRPPVATSPSQGPLPAVAGSS-GEEPWPWEGPSGRLG-AHVPD
TQVA------------MPLPHPLGHVSPQEESSCPGHGS---------------GGS---
------------------------------------------DSTGSFASGMAPARPRWN
THGHVSDASIRVGENVSDVAPARPRWS---THGHVSDASI-RLGENVSDVAPARPRWSTH
GHVSDASIRLGENVSDVAPARPRWSTHGHVSDASIR-----------------------L
GENVSDVAPARPRWSTHGHVSDASIRVGENVSDVAPAR-----PRWSTHGHVSDASIRLG
ENVLDVAPARPQRHAHRCAPQSHLMLRA---------------------------RSPET
EAT-----VPSP----SPTVSQSGLS----------------------LGTQSPALEQES
SFQTSP-------------------------------------------------WALAG
LHTLTD-----------------------GVPKEPAGCGPQIPCCPCAHAGP-RSGDTE-
----------DVSPSCLP---------SSQGRSAAQSSPGSSEAEAQ-----AEAARRWD
REQAYLAGLASQYHLEQYPDSYEAMSEPPAAHLIHHLLPRAFALPVDPQVQ---SAVDET
AVQLSE

PF04130 // ENSGT00850000132278_2_Domain_2 (1747, 2024)

LLTLPVLMKRSLSAPLAAHISLVNKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLSLNTALSKALRCSLHGDAPHAANLSFALKYLPEA
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLSKYGAIFSFLLQLKLMMWTLKDICFHLK
RTAA---LLSHAACSVQFRQLQLFKHEMQHFVRVTQGYVASQILHVSWCEFRARLAEVGN
LEELQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SVFSLVRKFRSQLISQ----------AEHPNFALMQQSYQAFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

MASITQLFDDLCEALLPAAQ--ARPGQRSVNRKRAKRSLKRVAYNALFANLFQEDTHQRQ
PDSSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEAAP--DCPFVEVASVLDLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNIPYSGYDCYDLSVFEMDVRSFISGEENLCHHTVQ
EALQVMEAAPGTGLPTV--GLFSIGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLT
YEASKR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-FCRLRHGELQAL-SGGL
LQAPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCRPTQAFVVEPGVHVSGASPESISSIL
SEVAEYGTCYTRLSHFSLQPVVGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSLAT-SGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSCISKEEKELRMEIAKQELIVHAREAASRVLSELSD
RQMAEQIAQDTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDQKCIQEMLRD
M--EAQQPQE--PPSVFPS-TGSQVTST----GPEH---------AGEGHSCDPGF----
---TELHWGCPSLPCASTPSVPKSA-----TE-GADDS-G------AGPFSTGLSITDFL
PVDSG------------------EEQPVENTGVPFLEVALQTICSDLSPVA---PEPAAL
TAGGPQATQSEYDFNTILRPAMATSLSPGPFQDVQNSVDSDKQHLLGDMSTKVD-SYIHD
MQ------------ETLPCPHPLSHATPVEGSLQPVGQLLEHMS----------ETTVST
ESHASGMAPCQQL--SISRHV---SDANIKV--------------GDYMSDVALPRPRWN
VHGHVSEASIGVGENMAEVAPSRPRWN---VHGHVSDASI-KIGENMSDVAPSRTRWNIH
GHVSDASIKVGENVSDVTPSRPRWNVHGHVSEASIK-----------------------V
GE---------------------------NVSDVTPSR-----PRWNVHGHVSEASIKVG
ENVSDVTPSRPRWNVHGHVSDASIRIGENVSDTDLDL--QQRGCA-QP-PLILEEPLPEA
EAD-----L-KPHQCPPAHVSEAVLG----------------------VEAQSPALECGP
----QLPEKTK-----PTVCSG-FGRTEEGSL----------------------------
----------------QTK-T---------LVAEPSMLGS----GIPEEKGPGKSRDAE-
----------DLSPCLPS---------SSQEDTAVPSSPGPSDEVSNTEA----EARRWG
KEQAYLTDLTKLYHLEQYPDSYDSMSEPPVAHLVHHMLPRAFAFPVDPQVQ---SAVDES
AVQLSELLTLPVLMKRSLMAPLAAHVSLVSKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHASNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQNWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASITQLFDDLCEALLPAAQ--PRPGQRSVDRKRTKQSLKRVAYNALFTNLFQEDARPLQ
SDLSKLPVRNKVLMLSFDLRVGGLGPEADRLEELVEGLEAAP--CCPLLEVGSVLTLLVQ
LAGSGPPQILQRKRDYFFNNKHAGRNVPYSGYDCCDLSVFEMDVQSFISREEHLCHSMIQ
ETLQVMEAAPGTALPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLDFPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSMTPDVDLWEAALT
YEVSKR------RCWERIG-CPP-GHREEPYLTEAGRDTFDR-FCRLRQEELQVL-SGGP
LQAPRPVLVTEQELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVASATFSLCQPAQAFVVARGVHVSGASPESISSIL
SEVAAYGTCYTRLSHFSLQPALGSSCSRGLVFQAFTSGLRRYLQYYRACVLATPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAMLLGTGGGEP-----RAVFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIRDWVYSGVLGDVYGEFMIQGNDEYLGCRDKSYWTH
GFALISKEVEDCVPVFLRHVAHDVYICGK-TINLLKLCCPQHYLCWSDIPVPRISVIFSL
EELKEVEKDCAVY-VGRMERVARHSSISKEEKELRMEIAKQELIAHAREAASRVLRELSD
RQTSEQMALDTRKREQFQRLKEQFVKDQERRLAARQEELDEDFSYAPE---------ALE
EELEKKARQALVDHYSKLSAEAARREQKALWRVQRHRLGSARLH-FLLDDEKCLQEMLRD
M-SEACRPQE--PLGVLPL-ARSQV--L--SASPEH---------SDGGQSCDPGP----
---PKQPEDYLGRLNAPALQPLQSP------------------AEGARPFSAGLSITDFL
PAGSG------------------AEQPVQD-GTPLLDHALQAICSDLFLSP---TVKAPS
AEGTLPVQPQEYDFSTILRPAPIALLSPESPQ-AV--KGSEEQQLWVDTRVTPD-ECAPD
TQVPL------------PCPLR--HGATQESSSQPPGWSPSTTL----------EATAPA
------------------------------------------EDEAWATQESSSQPPGWS
PSTTLE-ATAPAEDCAAGTAASRPRWN---IHGHVSDASI-RVGENVSDVAASRPRWNIH
GHVSDASIRVGENVSDVAASRPRWNIHGHVSDASIR-----------------------V
GENVSDVA---------------------------ASR-----PRWNIHGHVSDASIQIG
ETVSDVASSWPCWDAHTT---------------------------QPT--------FLEP
-----ESNPPRLPYSRPSHRSQPGSL-----------------------EIESPALECGP
----PLRTEAE-----PATRSPGAGS-----------------------------WEDGG
VQDLPF------------------------AVAKPGALGE----SVLQEPGPGWSRDTE-
----------DLSPRRPL---------DSQEDTAAPGCPGPGEVE--AEADTEVEARRQG
EEQAYLAGLARLYHLEQYPDSYEAMSEPPVAQLVHHVLPRAFTFPVDPQVQ---PAVGET
AVQLSELLTLPVLMKCSLTAPLAAHVSLVNKAAVDYFFVELHLESHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLALNCILSKALQCSLRGDSPHAAGLSFALKHLPEV
FAPNTPDVLSCLELRYKVD-WPLNIIITESCLSKYGAIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHAAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFRARLATVSN
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPATGPQGTEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

MASITQLFDDLCEALLPAAQ--PRPGQRSVDRKRAKQSLKRVAYNALFTNLFQEDSRPLQ
PDLSKLPVRNKVLMLSFDLRVGGLGPEADRLEELVEGLEAGP--CCPLLEVGSVLNLLVQ
LAGSGPPQILQRKRDYFFNNKHAGRNVPYSGYDCYDLSVFEMDVQSFISREEYLCHNMVQ
ESLKVMEAAPGTALPTI--GLFSFGDPCGDRFERDTRVSLFGALVYSRTYDMDVRLDLPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQCEPSMTPDVDLWEAALT
CEVSKR------RCWERIG-CPP-GHREEPYLTEAGRDTFDR-FCRLRQEELQVL-SGGL
LQAPRPVLVTEQELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVASATFSLCQPAQAFVVVRGVHVSGASPESISSIL
SEVAVYGTCYTRLSHFSLQPALGSSCGRGLVFQAFTSGLRRYLQYYRACVLATPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAMLLGTGGGEP-----RAAFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVCGEFMIQVNDEYLGCRDKSYWTH
GYVLISKEVEDCVPVFLRHVAHDVYVCGK-TINLLKLCCPRHYLCWSDIPVPRISVIFSL
EELKEVEKDCAVY-VGRMERVARHSSISKEEKELRMEIAKQELIAHAREAASRVLRELGD
WQTSEQMALDAQKREQFQRLKEQFVKDQERRLAARREELDEDFSYAREFRDREKRLKALE
EELEKKARQALVDHYSKLSAEAARREQKALWRVQRHRLQSVRLR-FLLEDEKRLQEMLRD
M-SEDRQPQE--PLGVLPL-TCYQV--L--SAIPEH---------SDGGCSCDPGL----
---PEQPRDCLGRLNASVLQPLRSP------------------VEGAKPFSSGLNITDFL
PAGSG------------------AEQPVQD-GTPLLDHALQAICSNLLPSP---TVEVPS
AEGTLPIQPQEYDFSTVLRPAPTAMLSLESPQ-DV--KGCEEQQLWVDTGVNPG-ECAPD
TQVPL----------HPPCPLT--HGATQESSSHLPGWSLSPML----------EAAAPT
------------------------------------------EDSAAGTAV---SRPRWN
IHGHVSDASIRVGENVSDVAVSRPRWN---VHGHVSDASI-RVGENVSDVAVSRPRWNIH
GHVSDASIRIGENVSDVAVSRPRWNIHGHVSDASIR-----------------------V
GENVSNVAASRPRWNTHSHVSDACIQTGETVLDVAASR-----PCWNVHGHVSDASIQVG
ETMSDVAFSQPCWDGHTT---------------------------QLT--------FLEP
-----EFNLPRLSYSLPDHRSQVGSL-----------------------AAESLAREYGP
----PLCAEAE-----PATGSPGAGG-----------------------------REEGG
LQGSPS------------------------PVATLGALGG----GVIEEPGPGWSRDIE-
----------DLSPHQPL---------DSQAA----------------DVDVEAEARRWD
EEQAYLAGLARLYPLEQYPDSYEAMSDPPAAHLVHHVLPQAFTFPVDPQVR---PAVGET
AVQLSELLTLPVLMKYSLTAPLAAHVSLVNKAAVDYFFVELHLESHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLALNCVLSKALQCSLHGDSPHAAGLSFALKHLPEV
FAPNTPDVLSCLELRYKVD-WPLNIIITESCLSKYGAIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHAAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFRARLATVRD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPASGPQGTEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLHQGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKLYWTH
GYVLISKEVEDCVPVFLKHIAHDIYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
V-SEAHQPQE--PPDVLLS-VHPQVTSP----GPEH---------PEGGQGCDSGS---A
-EQHSPAWDGWNRPGLLTPQPLKPL-----AV-GAGGR-GLQQAEGARPFSDSLSIGDFL
PVGPG------------------AEPSVQTGMVPLLEVALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDSCGKMD-ACGSA
S---RET---------LLPSHPPRRAALEEGSSQPTERLFGQVS----------GGGLPT
GDYASEIAPTRPRW-NTHGHV---SDASIRV--------------GENVSDVAPTQPRWN
THGHVSNASISLGESVSDVAPTRPRWN---IHGHVSNASI-RVGENVSDVAPTRPRWNTH
GHVSNASIRVGENVSDVAPTRPRWNTHGHVSDASIS-----------------------L
GESVSDMAPARPRWNTHGHVSDASISLGESVSDMAPTR-----PRWNTHGHVSDTSIRVG
ENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVVSTRPRWNTHVPIPPPHMVLGALSPEA
EPNT-----PRPQQSPPGHTSQSALS----------------------LGAQSTVLDCGP
----RLPVEVG-----PSLSSPSSGCGEGSI-----------------------------
---------SVGENVSDVAPTQPW------WPNT---PGD----SVSEELGPGRSGDTE-
----------DLSPNWPL---------NSQEDTAAQSSPGRGEEA-E-----ASAAEAQG
GEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITEGCVSKYSGVFSFLLQLKLMMWALKDVCFHLK
RTA----LLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAQ--PRPGRRSADRRRAKQSLKRVAYNALFTSLFQEDARPLQ
PDLSKLPVRNKVLMLSFDLRAAGLGPEADRLEELVAGLEAAS--CCPLLELGSALKLLVH
LAGSGPPQLLQRKRDYFLNNKHAGRNVPYSGYDCCELSVLETDVQSLVSAEEHLCHSMIQ
QTLQVMDAAPGAGLPTV--GLFSFGDPCGDRLERDTRVSLYGAFVHSRAYDVDVRWDLPP
VPDSADLSGL------AIKVPQNVDQWEDEGFQSASNLTPDSQSEPSMTPDVDLWEAALT
YEVSRR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQEELHVL-SGGL
LQAPRPVLVTEQELVK

PF04130 // ENSGT00850000132278_2_Domain_1 (377, 743)

DSLNVL-LGVASATFSLCQPAQAFVVAQGVHVSGASPESISSIL
SEVAAYGTCYIRLSQFSLQPALGSSCSRGLVFQAFTSGLRRYLQYYGACVLATPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGALLPGTGGGEP-----GASFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVCGEFMIQVNDDYLGCRDKSYWTH
GYVLISKDVEDCVPVFLRHVAHDVYVCGK-TINLLKLCCPQHYLCWSDIPVPRISVIFSL
EELKEVEKDCAVY-VGRMERAAHHSSLSKEEKELRMEIAKQELIAHAREAASRVLRELSD
RQTSEQMVLDARKREQFQQLKE

ENSGT00850000132278_2_Linker_1_2 (743, 1796)

QFVKDQERRLAARQEELDEDFSYARELRDREKRLQALE
EELEKKARQALVDHYSKLSAEAARREQKALWKVQRQRLESARLR-FLLEEEKRLQGMLRD
K-SEARRSQE--PLDILPL-ACSKVW-----TCLEH---------SDGGQSYDAEP----
---PEKPGDCLGRSDAPGPQALQPP------------------ADGSGLFSAGLSIVDFL
PAASG------------------AEEAVQD-CPPLLDQALRTICSDLLSSS---MVEAPS
AEGPVPAQPQEYDFSTVLRPAATATLSPEPLNAAN--KGSEEQQLWVDTCGRSE-ECAPD
THRP------------PPLPGLPLHGAAQEASSQLSEWSLVPTS----------GAATWT
------------------------------------------MGCASG---MAASHPHWN
VHSNVSEDIIQVRDNVSAVATSQPRWN---IHSHMSDDSI-RVRENVSDVATSRPRWNIH
GHVSDASIRVGENVSDVATSRPRWNIHGHVSDANIR-----------------------V
GENVSDVATSRPRWNIHGHVSDASIRVGENASNVATSR-----PRWNIHGHMSDSSIQIG
ADVLNLASSRPCWDGHTT---------------------------QPL--------SLEA
-----ESNVPWLPCSLPGQGSQPGIP-----------------------KPKSTALECGP
----LLSTEVE-----PATCTLGAGS-----------------------------WEEGA
LQASLS------------------------AK----------------------NEDTV-
----------DLSPPQPL---------DPQGDTSPQEQPGPGEEE----AEAEAQSWRRG
EEQAYLAGLARLYPLEQYPDSYEAMSEPPVTHLLHHVLPRAFTFPVDCWAQ---PAVEET
AVQLSELLTL---------------------------------------------

PF04130 // ENSGT00850000132278_2_Domain_2 (1796, 2024)

-PDGE
FAQSLSDLLFEKLAAGQSPGELLSPLALNCILSKALQCSLHGDSPHAAGLSFALKQLPEV
FAPNTPDVLSCLELRYKVD-WPLNIVITESCLSKYSAIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHSAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFQARLVTVSD
LEEIQRAHAEYLHKAIF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWVPVSGSQDTEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

MASITQLFDDLCEALLPAAQ--ARPGQRSVNRKRAKLSLKRVAYNALFANLFQEETQQRQ
PDSSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEAIP--GCPFVEVECVLDLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNLPYSGYDCYDLSVFEMDVRSLISGEEYLCHNMVQ
EALQVMESAPGTGLPTV--GLYSIGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWETVLT
YEASKR------RCWERIG-CLP-GHREEPYLTEAGRDAFDR-FCRLCHGELRAL-SGGL
LQGPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSFCQPTQAFVVELGVHVSGASPESISSIL
SEVAEYGTYYTRLSHFSLQPVIGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVSLAT-SGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERLARHSSISKEEKELRMEIAKQELIVHAREAASRVLRELSD
RQMSEQMAVDTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLQ-FLLEDQKRIQEMLRD
M--EAHQPQE--PPSMFPS-TCSQVTSP----CPEH---------ADEGRSCDLGS----
---TELQWNC--PSGTSTPSVLKSA-----AE-GADDS-GTGQAEGAGPFSSGLSITDFL
PTGPG------------------AEQPVDNTGAPFLEAALQTICSDLPPIT----GPT-L
TAADPQPTQSEYDFNTILRPALAASSSPGPFQDVQNGLDSETQYVLGDMPTKLN-ACVHD
VQ------------ETLPCPHPLKHVTPEEGSFQPVGQFLEHMS----------GTVIPT
ESLASGMAPCQQLR-SISRCV---SDANTKG--------------EDYMSDMALPRPQWN
ICGPVSEASIGVGENVSEVASSRPRWN---VHGHVSDASI-KVGENVSDVAPSRPRWNIH
GHVSDASIKIGENVSDVAPPRPRWNVHGHVSEGSIK-----------------------I
GENVSDVAPSRPRWNIHGHVSDASIKVGENVSDVAPPR-----PRWNVHGHVSDASIKVG
ENVSDVAPPRPRWNVHGHVSEASIRIGENVSE--EAP--QPHGCT-QP-PLILEEPLPEA
EPD-----LLKPRQCSPAHVSQSGLG----------------------VEAQSPTLECGP
----QLPGETK-----PTICSS-PGSIEEGSL----------------------------
----------------ETMPP---------VVAEPSILGN----GILEETGPERSRDAE-
----------DLSPWPP----------SSQEDTAVPSSPGPSEEVSDTEA----EARRWG
KEQAYLADLTQLYHLEQYPDSYESMSEPPVAHLVHHMLPQAFAFPVDPQVQ---SAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVTLVNKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHATNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTGGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVSD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQTWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------PP-GHGEEPYLTEAGRDAFDR-FRRLHHDELRVL-GGGL
LDTLPPVLVKECE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1703)

LVKDVLNVL-LGVLSATFSLCQLTQAFVVTRGTHVSGASPESVSSLL
SEVAACGTHYMRLSHFSVQPTQGT-CCRGLVFQAFTSGLRRYLQYYRACVLATPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSPGAGGGEP-----RVPFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKASCEPYTRFIHDWVYSGVFRDTYGEFMIQVNHDYLGFRDKSYWTH
GYVLISKEVEDCVPVFLRDIAQDVYVCGK-TINLLKLCCPRHYLCWSEVPVPRISVLFSL
EELRELQKACALY-VGRMERVARHSSVSKEQQELRMEIAKQELVVHAWEAASRVLRELSD
RQMSERMALDARKREQFQKLKEQFVKDQERRRAARQEELDDDFSYARELRDREKRLRALE
EQLERTARQALVEHYSRLSGEAARREQRALWRVQRHRLASARLR-FLSEDQKHLQGMLKD
M-AEGKEPPA--PTPLRAE---PQASSPEGSPGPEQAAQ---------------------
--RLAAASDSPSR-----SQPLE--------S-APGETCSPEPRVVLGPFSEGLSIGDFL
PXXXX------------------XXXXXXXXXTPVLEEALQTIGSDLPLSP---------
------AGPPDYDFRTILRPALATLAPPGPLQTAGE---------WRLP-GEQS-AAPRG
R------------------------SRSDLQQSQAVEQ----------------------
---------------------------------PPGLMLEGGDGKQGEAAGSAAPRPRWN
VHGHVSDASIKVGEHVWDVAPSRPRWN---VHGHVSDASI-KVGEHVWDVAPSRPRWNMH
GHVSDASIKVGEHVWDVAPSRPRWNVHGHVSQSQVS------------------------
--------------------------LGAQEHSTLTRSDLGALPEHSTPR----------
---------------------------------------SKHSPLTQELQALLGAPISG-
----------------------PGAQ---------------------HP-----------
--------DPGA----PALISPIADTGELISD----------L--GAQHSDLALTWEHST
PGAP----------VSDLG-----------------------------APGPRKT-----
-------WTEDPAPGSLP---------IFQGGAAAQSSPSLGSQRQQD--LEEEEAEALR
REQAYLERLAGQYRLEHYPDSFTAL-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

MASVPQLFDDLCEALLPAAK--AHLGQHGVSRKRAKQSLKRVAYNALFTNLFQDETHKLQ
ADLSKLPVKNKIFMLSFDLRVGGLGPEADRLEELVEELLAAP--CCPLVEVGSVLDLLVQ
LAGSGPPQVPQRKRDYFFNNKHVGRSVPYSGYDCCDLSVFEMDVQSLISREEYLCQDMIQ
KALQVMEAAPGSGLPTV--GLFSYGDPWGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
MPDSADLSGL------AIKVPQSVDQSDDEGFQSASNLTPDSQSEPGMTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDTFDR-FCRLCHGELQVL-GGGL
LQAPQPVLVKECE

PF04130 // ENSGT00850000132278_2_Domain_0 (374, 1972)

LVKDALNVL-IGVVSTTFSLCQPAQTFVVRRGVHVSGASPEGISSLL
SEVAECGTHYTRLSRFSLQPVLDSSCSKGLVFQAFTSGLRKYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTALPGSSGGEP-----ETAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEACVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLYWSDVPVPRISVIFSP
EELKEVERDCAIY-VGRMERVARHSSISKEEKELRMEIAKQELIVQAREAASRVLRALSD
RQTSERRALDARKREQFQRLKEQFVKDQERRRAARQEALDGDFSYARELHDRERRLRALE
EQLERKARQALVDHYSKLSAEAARREQKALWKLQRHRLASARLR-LLVEDQQHIQGMLKD
V-SEGKAPE---PPAVLPA-AGSQAPSP----GPEH---------PAGGCSHDAGYA---
EQQHVAAWGGP---NAEEPRQLRPPAAGACGS-GPGAEPQPGLVDGPGPFSEGLSIQDFL
PAARE------------------AEPPTHTGAAPVLEEALQTIGSDLPPSA---PSEA--
-TGPGPSGPQEYDFRTILRPAIAPLASPGSQQTVGGSLRNGGQQLWGDSVTQPEDTGASD
RQV------------ALPHPQTPAHTLPQDGSSQAVGQLLRQAS----------EGSVPT
---------------------------------------------GGCVSGIALSRPRWN
VHGHVSDASIKVGENVWDVAPSRPRWN---VHGHVSDASI-KVGENVWDVAPSRPRWNVH
GH----------------------------------------------------------
-------------------VSDASIKVGENVWDVAPSR-----PRWNVHGHVSQSCVVLG
AVSGESQPNTPRPC----------------------------------------------
-------------QSPPNHVSQPGLS----------------------LGAQSPVWEQEP
----RLPAEMASDSSCAQVAGSSSGEASGLQAPPSAVAASGDLGDSNPK-----------
------------------------------------------------EPGPETSGDTE-
----------DLSPSRPP---------HSQEGAAAPGSPSLGEGE--------AAAQRWG
QEQAYLAGLAEQYRLEQYPDSYEAMSEPPVAHLLHHGLPRAFALPEDPRVR---SDADET
AVQLSELL-FPVLMKHSITAPLAAHVSLVNKAAVDYFFVELRLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQYSLHGDTPYAANLSFALKFLPEA
FAPNAPDVLSCLELRYKVD-WPLNVVVTEGCLSRYSGIFSFLLQLKLMTWTLKDICFHLK
RAA----LRSHAAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFRARLARVGD
LEEIQRAHAEYLHKAVF--------------------------RWGLLTERAAPVMNVIH
SV--------------------XPRGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FK-------------------------------
----------------------------

MASITQLFDDLCEALLPAAK--TLLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PNMSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPLQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPP
VPDNAELSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLHQGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAYDIYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHIQEMLKA
V-SEAHQPQE--PPDVLLS-VHPQVTSP----GPEH---------PEGGQGCDSGS---A
-EQHSPAWDGRNRPGLLTPQPLKPL-----AV-GAGGT-GLQQAEEARPFSDSLSIGDFL
PVGPG------------------AEPSVQTGMVPLLEVALQTINLDLPPSA---PGEAPA
AASTQLSRPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDSCGKMD-ACGSA
S---RET---------LLPSHPSRRAALEEGSSQPTERLFGQVS----------GGGLPT
GDYASEIAPTRPRW-NTHGHV---SDASIRV--------------GENVSDVAPTRPRWN
THGHVSNASISLGESVSDVAPTRPRWN---IHGHVSNASI-RVGENVSDVAPTRPRWNTH
GHVSNA------NVSDVAPTRPRWNTHGHVSDASIS-----------------------L
GESVSDVAPARPRWNTHGHVSDASISLGESVSDMAPTR-----PWWNTHGHVSDASIRFG
ENVSDVAPIRSRCNTHGHMSDASISLGEPVSDVVSTRPRWNTHVPIPPSHMVLGAPSPEA
EPNT-----PRPQQSPPGHTSQSALS----------------------LGAQSTVLDCGP
----RLPVEVG-----PSLSSPSSGCGRGAS-----------------------------
---------V-------------R------WMQP---GGP----TA------GREGSVP-
---------LGSCSGEVV---------LRLEDTAAQSSPGRGEEAEAS----ASAAEAQG
VEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITEGCLSKYSGVFSFLLQLKLMMWALKDVCFHLK
RTA----LLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MGVS
PVPVPASPAGSRARL---------RLQLGPAGTGS-----CTVP

PF04130 // ENSGT00850000132278_2_Domain_1 (525, 746)

LQGVKLLSYLYEEALN
NCSNEYYPVLLSLLKTSCEPYTRFIYDWVYSGVFRDTYGEFMIQVNEEYLSFRDKHYWTH
GYVLISKEVEDCVPVFLKHIANDVYICGK-TINLLKLCCPRHYICSSDIPVPRISVIFSL
EELKEIERDCALY-VGRMERIARYSSVSKEEKGLRMDVAKQELAVHAREAAREALKAVSD
RQTAARVALDAKKRRQFQRLKEQFERDRERRLAAKQEEADDDFGYARELRERESRLKALE
EELERKARQELMERYSKLTAEAAGREQRALWTVQRHRLDAARLS-FLLADQKRIQEMLDS
V-ARGEAPGE--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGRGPEADRLEELVEELEAAP--CCPLLEVGSVLDLLVQ
LAGSGPPQLLPRSRDYFLNNKHVGRNVPYSGYDCDQLSVSETDARSLISREECLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPP
VPDNADLSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AAGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSSYSKGLVFQAFTSGLRRYLQYYRACVLSTSPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAVLPGTCGGGP-----RAAFPTGVKLLSYLYQEALH
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHDYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDEKHTQEMLKA
M-SEAHQPQE--PPHVLLS-VHSQVTSL----GPEH---------QEGDQGCDAGP---A
-EQHSAAWDGRNRPGLLTPQSLKPV-----AM-GAGGT-GLQQAEEAGPFSDSLSIGDFL
PVGPG------------------AEQSVQTGMVPLLEAALQTINLDLPPSA---PGEAPA
AASTQPSRPQEYDFSTVLRPAVAASPAPGPLKAAECNLGSSGPQLWEDSCGKLD-ACGST
L---QVA---------LSPSHPPRRAALKEGSSQPTEQLFGHES----------GGGLPT
GGCASEIALTRPQW-NIHRHV---SDASIRV--------------GENMSQVAPTRPRWN
IHGHVSDASIRVGENVSDVAPTRPRWN---THGHVSDASI-SLG----------------
-----------ESVSEAAP-----------------------------------------
------------------------------------------------------------
--------TRPRWNIHGHVSDTSISLGEPVSDMVSTRPRWNTRAPAPPSHMMLGTVSPEA
EPNT-----PRPQQSPPGHTSQSALS----------------------PGAQSTVLDCGP
----RLPVELG-----PSLSSPSSGCREESI-----------------------------
---------SIGENVSDVAPTRPW------LPNT---PGD----SVSEELGPGRSGDTE-
---------------EPL---------NSQENTAAQSSLGPGEEA-------AVAAEAQG
GEQAYLADLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKHSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNVVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

MASITQLFDDLCEALLPAAQ--ACPGQRSVNRKRAKRSLKRMAYNALFANLFQEDTHQRQ
PDSSKLPVKNKILMLSFDLRVGGLGPEADRLEELVEKLEAAP--DCPFVEVPSALDLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNVPYSGYDCHDLSVVEMDVRSFISGEENLCHHTVQ
EVLQVMEAAPGTGLPTV--GLFSIGDSCGDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLT
YEASKR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-FCRLRHGELQTL-SGGL
LQAPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQPTQAFVVEPGVHVSGASPESISSIL
SEVAEYGTCYTRLSHFSLQPVVGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSLAT-SGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSCISKEEKELRMEIAKQELIVHAREAASRVLSELSD
RQMAEQIALDTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDQKCIQEMLRG
M--EAQQPQE--PPSAFPS-TGSQVTSP----GPEH---------TGEGHSCDPGS----
---TELHWDCLSLPCASTPSVPKSA-----AE-GADDS-GAGQAEGAGPFSTGLSITDFL
PVGSG------------------EEQPVENIDAPFLEVALQTICSDLSPVT---SGPLAL
TAGGPQPTQSEYDFNTILRPAMATSLLPGPFQDVQNSVDSEKQHLLGNMPTKVD-SCIND
MQ------------ETLPCPHPLSHATPVEGSLQPVGQLLEHMS----------ETTVPT
ESHASGMAPCQQL--SISRHV---SDANIKL--------------GDYMSDVALPRPRWN
VHGHVSEASIGIGENIAEVAPSRPRWN---VHGHVSEASI-TIGENMSDVTP-QPQWNIH
GHVSDASIKVGENMSDMTPSRPRWNVHGHVSDASIK-----------------------V
GE---------------------------NVSDV-------------------------G
ENVSDVTP-RPRWNVHRHVSEASIRIGENASD--VDL--QQRGCA-QP-PLILEEPLPEA
EAD-----L-KPHQCPPAYVSEAVLG----------------------VEAQSPALECGP
----QLPEETK-----PT---------EEGNL----------------------------
----------------QTK-I---------LVAEPSMLGS----GILEEKGPGRSRDAE-
----------DLSPCLPS---------SSQEDTAVPSSPGPSDKISNTEA----EARRWG
KEQAYLTALTKLYRLEQYPDSYESMSEPPVAHLVHHMLPRAFAFPVDPRVQ---SAVDES
AVQLSELLTLPVLMKRSLMAPLAAHVRLVSKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHASNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGD
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQNWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASITQLFDDLCETLLPAAR--ARPGQRSVSRKRAKLGLKRVAYGALFTNLFLEEPRERK
PDLQKLPVKNKVLMLSFDLRVSGLGPEADRLEELVEKLEAAP--G-PFVEVGSVLDLLVQ
LAGSGPPQTLRRKRDYFFNNKHAGRNVPYSGYDCDGLSVFEMDMQWLISGEEYLCHNTIQ
EALQVMEAAPGTGLPTV--GQFSTSDPC-DRFVRDTRVSLFGGLVHCRTYDMDVRLDLPP
VPDSADFSGL------AITVPQSIDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAALT
YEASKR------RCWEHIG-CPP-GHRDEPYLTEAGRDAFDR-FCRLRHGELQVL-SEGL
LQAPKPLLVTESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQPAQAFVVERGVHVSGASPESISSIL
SEVAEYGTYYTRLSHFSLQPVLGSMCSRGLVFQAFTSGLRRYLQYYRACVLSTPATLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVPLAN-GGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTQFIHDWVYSGVFRDIYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDIPVPRISVIFSL
EELKEIEKDCAVY-VGRMERIARHSSISKEEKELRMEIAKQELIIHAREAASRVLSELSD
RQMSEQRAADTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLC-FLLEDQKRIQEMLRD
M--ETCQPQE--PSSVLPS-TCSQITSS----GPEQ---------ADEDCSSDLGS----
---TEQHWDCPNPSNTPTPQALTS------------------AAEGAGPFSAGLSITDFL
PIDPR------------------AEQPVGASGTLCLEVALQTICSDLPPVT---PGVA-L
IEADPQPIQPEYDFNTILRPAP----SLGPLQDVQGSLSTEKQHLLGDIDMKLG------
-----------------------AHVAPEEGSCWQVGQLLEHLS----------GTASLI
DSHASGMASCQQPW-SISRHV---SDSSIKV--------------GENVSDVAPSRPRWN
VHGHVSDASIKIGENVSDVAPSRPRWN---VHGHVSDASI-KVGANVSDVAPTRPRWNVH
GHVSDASIKVGANVSDVAPSRPRWNVHGHVSDASIK-----------------------I
GE---------------------------NVSDVAPAR-----PRWNVHGHVSDASIKVG
ANVSDVPPSRPRWNVHGHVSDASIKVGANVSGMAP----QPCGHTSQC-PMIL-----EV
EPD-----LPTPPQSSLDSVSQSSLS----------------------LEAQSPALEYGP
----QLPGEME-----PTICSPSPSRREEGSL----------------------------
----------------QTKNP---------VVAEASTLGN----GVPKETDQERRGNTE-
----------DLSPRWPP---------SSQEGTAAPNSPGPIEEVSDTET----EATHWG
KEQAYLADLTRLYHLEQYPDNYESMSEPPVAHLVHHMLPRAFAFPVDPQIQ---SAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVSLVNKAAVDYFFVELHLDAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHATNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLSKYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGD
LEEIQRAHADYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPASGPHGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

------------------------------------------------------------
-------------MLSFDLRVGGLGAEADRLEELVEGLEAAP--RQPLAELGAVLELLVR
LAGSGPPRVRRRRRGVFLHSRPVGRALPYGGYDCADLSELEADVRSLISGEESLCRDLVR
KTRQVMESAPGTGLPAV--GLFSYGDPCWDRFERDTRVSLFGALVHSRTADLDVRLDLPP
VPDSADLSGL------AIKVPPSVDQSEDEGFQSASNLTPDSQSEPGVTPDIDLWDAVLT
YEASKR------RCWEQVG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQGELQVL-GGSL
LQAPQPVLVKECEL

PF04130 // ENSGT00850000132278_2_Domain_0 (375, 2024)

VKDALNVL-IGVVSATFSLCQPAQAFTVKRGVHVSGASHESISGLL
SEVAECGTHYARLSHFSLQPVLDSSCSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGATLQGSGGGEP-----RAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGFRDRLYWTH
GYVLISKEAEDCVPVFLSHIAHDVYVCGK-TINLLKLCCPQHYLCCSDVPVPRISVTFSL
EELKDIEKDCATY-VGRMERVARHSSVSKEEKELRMEIAKQELIVQAREAASRVLRALSD
RQMSERMVSDARKREQFQRLKEQFVKDQERRRAARQEELDEDFSYARELRDRERRLRALE
EQLERKARQALVDHYSKLSAEAARREQRSLWKVRRHRLASARLR-FLLEDEKRIQGMLEA
V--AEGRPLE--QPAILPG-ACSQTSAHS--RAGDQASFLGP-VPPDRGGSCDPGREE--
--PREAAPAGPHGQSTLTLQPLKSPGAGAYGT-GPGAGLLWGQAEEPGPFT-GLSLRDFL
PAAQGAEAG------------------L-SGTAPVLEEALQTIGSDLPPMAPSTAM----
--DLTPVRPQEYDFRTVLRPTVAASGSAGALQTAGGSPGSRGQQLQEDTQVPLD-TCGLD
PPQH---------------------PSPQEERCPATAQVLG-------------------
--------------------------------------AEPGVPRGGCASGMTPSRPRWN
------------------------------VHGHVSDASI-RVGENVWDVAPSRPRWNVH
GHVSDASIRVGENVWDVAPSRPRWNVYGHVSQSSVVLGVLSGEAEPNLP-----------
------------------------------------------------------------
------------------------------------------------------------
----------RPPLCPPDPGPQLGLS----------------------SGAQGPAQEHTL
----QLPAETASGSSSAQVVGPGPGHGEEGG-----------------------------
PQASLS------------------------AEAVPAALGD----GTLEEPGTALSWDWAG
R--------A--ACWSLL---------SHEENADVQSSPDAGEA----------AAQLWD
REQAYLVGLAGQYRLEQYPDSYEAMSEPPVARLLHHGLPRAFALPEDAGVP---SDADES
AVQLSELLPLPVLMKHSVTAPLAAHVSLVNKAVVDYFFVELNLGAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLVLNSVLSKALQYSLHGDSPHAANLSFALKFLPET
FAPNAPDVLSCLELRYKVD-WPLNIVVTEGCLSRYGGIFSFLLQLKLMMWTLKDVCFHLK
RTAR----VSQAAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFQARLASVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNVIH
SVFSLVLKFRSQLISQPWGPAGGPRGPEHPNFALMQQSYSAFKYYSHFLFKVVSKLVNRG
YQPH---LEDFLL-R-----INFNNY-----------------------------YQDA-
----------------------------

MASITQLFDDLCEAHLPAAK--AHLGQYGLDRRRAKQSLKKVAYNMLFTNLFQDETHKLQ
PDLPKLPVKNKILLLSFNLRVGGLGPEADRLEDLVEELEGAT--WCPLVEVLSVLDLLVQ
LAGSGPPQVLPRKRDYFFNNKHVGRNGPYSGYDCYDLSVFEMDVQSMIAREEYLCHDMVQ
KTLQVMEAAPGTGLLTF--GRFSSGDSC-DKFERDTRTSLFGALVHSRTFDMDVRLDLPP
VPDSADLSGL------AIKVPQSVDQSEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDR-FCRLCEEGLQVV-GGSL
LPAPQRVLVRECE

PF04130 // ENSGT00850000132278_2_Domain_1 (374, 688)

LVKDTLNVL-IGVVSATFSLSQSAQAFVVKPGVYVSGTSPESMRSLL
SEVAACGTYYVRLSRFSLQPVLDTTCSKGLVFQAFTSGLRRYLQYYRACVLSTPATLSLL
AIGFLFKKLGRQLRYLA-ELCGVGTGLPGTAGGGP-----RTAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPACRFIHDWVYSGLFRDIYGEFMIQVNHDYLGFRDKFYWTH
GYMLISEEVEDCVPVFLRHIANDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARYSSVS--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

MASITQLFDDLCEALLPAAQ--ARPGQRSVNRRRAKRSLKRVAYNALFANLFQEDTHQRQ
PDSSKLPVKNKVLMLSFDLRVGGLGPEADRLEELVEKLEAAP--DCPFVEVASVLDLLVQ
LAGSGPPQVLRRKRDYFFNNKHAGRNIPYSGYDCYDLSVFEMDVRSFISGEENLCHHTVQ
EALQVMEAAPGTGLPTV--GLFSIGDSCGDKFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADFSGL------AIKVPQIVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAVLT
YEASKR------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-FCRLRHGELQAL-SGGL
LQAPKPVLVEESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCRPTQAFVVEPGVHVSGASPESISSIL
SEVAEYGTCYTRLSHFSLQPVVGSLCSRGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTVSLAT-SGEP-----RAVFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLSFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSCISKEEKELRMEIAKQELIVHAREAASRVLSELSD
RQMAEQIALDTRKREQFQRLKEQFVKDQERRLAARQEELDDDFSYARELRDREKRLKALE
EELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLR-FLLEDQKCIQEMLRD
M--EAQQPQE--PPSVFPC-TGSQVTSP----GPEH---------AGEGHSCDPGS----
---TELHWGCPSLPCASTPSVPKSA-----AE-GADDS-G------AGPFSTGLSITDFL
PVDSG------------------EEQPVENTGVPFLEVALQTICSDLSPVA---PGPA-L
TAGGPQPTQSEYDFNTILRPAMATSLSPGPFQDVQNSVDSDKQHLLGDMSTKVD-SCIHD
MQ------------ETLPCPHPLSHATPVEGSLQPVGQLLEHMS----------ETTVST
ESHASGMAPCQQL--SISRHV---SDANIKV--------------GDYMSDVALPRPRWN
VHGHVSEASIGVGENMAEVAPSRPRWN---IHGHVSDASI-KIGENMSDVAPSRPRWNIH
GHVSDASIKVGENVSDVTPSRPRWNIHGHVSDASIK-----------------------V
G-----------------------------------------------------------
ENVSDVTPSRPRWNVHGHVSEASIRIGENVSDT--DL--QQRGCA-QP-PLILEEPLPEA
EAD-----L-KPHQCPPAHVSEAVLG----------------------VEAQSPALECGP
----QLPEETK-----PTVCSG-FGRTEEGSL----------------------------
----------------QTK-T---------LVAEPSMLGS----GIPEEKGPGKSRDAE-
----------DLPPCLPS---------SSQEDTAVPSSPGPSDVVSSTEA----EARRWG
KEQAYLADLTKLYRLEQYPDSYESMSEPPVAHLVHHMLPRAFAFPVDPQVQ---SAVDES
AVQLSELLTLPVLMKRSLMAPLAAHVSLVSKAAVDYFFVELHLETHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHASNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGN
LEEIQRAHAEYLHRAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQNWGPATGPRGAEHPNFPLMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS-
----------------------------

MASITQLFDDLCEALLPAAR--PRPGQRSVDRRRAKQSLKRVAYNALFTSLFQEDARALQ
PDLSKLPVRNKVLMLSFDLRVGGLGPEADRLEELVEALEATS--RSPLLEVGSVLTLLVQ
LAGSGPPQILQRKRDYFFNNKHAGRNVPYSGYDCYDLSVFEMDVQSLIAREEYLCHSMIR
ETLQVMEAAPGTGLPTV--GHFSFGDSCGDRFERDTRVSLFGALVHSRTYDMEVRLDFPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEVSKR------RCWERIG-CTP-GHREEPYLTEAGRDAFDR-FCRLRQEELQVL-SGSL
LQAPRPMMVTEQELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVASATFSLCQSTQAFVVAQGVHVSGASPESISSIL
SEVAAYGTCYTRLSHFSLQPALGASCGRGLVFQAFTSGLRRYLQYYGACVLATPSTLSLL
TIGFLFKKLGRQLRYLA-ELCGIGAILPGAGGGEP-----KASFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNDEYLGCRDKSYWTH
GYVLISKDVEDCVPVFLRHVAHDVYVCGK-TINLLKLCCPQHYLCWSDIPVPRISVIFSL
EELKEVEKDCAVY-VGRMERVAHHSCISKEEKELRMEIAKQELIAHAREAASRVLRELSD
RQTSEQMALDARKREQFQQLKEQFVKDQERRLAARQEELDEDFSYARELRDREKRLQALE
EELEKKARQALVDHYSKLSAEAARREQKALWRVQRHRLESARLR-FLLEEEKCLQEMLRD
L-SEVRHPLE--PPGVLPL-ACSE--DL--SGSLEH---------SDGGQTCDLGF----
---PEQPGDCRGGLNVLAPQPLQSP------------------AAGAGPFSAGLSIVDFL
PTDSR------------------AEQPEQD-GTPLLDQALQTICSDLLPSS---TTEAPS
AEETLPAQPQEYDFSTILRPAVTAALSLGPLQ-AV--RDSEEQQLCVNTRGRPD-ECGPD
IHRPL----------CLPHPLTHRHGTAQEANSQIPGGFLAPTL----------GAAAPT
------------------------------------------EGRATE------------
------------------TAASQPGWN---IHGHVSDSSI-QIGENVSDVAASRPRWNIH
GHVSDASIRVGENMSDVATSRPRWNIHGHVSDSSIQ-----------------------I
GENVSDVAASWPRWNIHGHVSDASIRVGENMSDVATSR-----PRWNIHGHVSDASIQIG
ENVSAVASSQPSWGGHTT---------------------------QPF--------FLEA
-----KSNPPRLPCSLPGQGSWPGTP-----------------------KVESSALECGP
----SISAEVD-----PATHCPGAGS-----------------------------WEDSS
LQATSC------------------------AIAEPGTVGD----SVSEQPGPGRNGDTE-
----------DLSACQPG---------DS-QDTATPGQPSPGEGEVEVDAEAEAEARRWG
EEQAYLASLARLYPLEQYPDSYEAMSEPPVTHLVHHVLPWAFTFPMGLQAQ---PAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVSLVNKAAVDFFFVELHLESHFEALRHFVLMEDGE
FAQSLSDLLFEKLAAGQTPGELLSPLALNGILSKALQCSLHGDSPHAAGLSFALKHLPEV
FAPNTPDVLSCLELRYKVD-WPLNIVITESCLSKYSAIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHSAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWAPASGPLGTEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

MASITQLFNELCEVHLGHVPWKTHPGRPGASMQRAKQGLKKVVYDALFMGLFQEEGHKLL
SAESQLPVKNKILMLSFNLRVGGLGPDADRLEELVDGLEAAPALGLPLTEIRAVLDLLVR
LAGSGPPVFLPQKRDYFLNNKHVGRNVKHQGYDYYDVSMFEADTRFLIASQEQQCWETVQ
KTLQVMEAPPGTGLRSI--GLFAHNYPGVDRFERETHGSLFGALVHSHTYDMDIKLDLPP
VPDSADLSGL------AIQVPQSIDQSEDEGFQSASNLTPDSQSEPSMTPDIDLWDAVLT
YEPSKR------RCWERIG-CPP-GNKEEPYLTEAGREAFDM-FYRLREGELQLL-HSGL
FQLPSLFLMKERDL

PF04130 // ENSGT00850000132278_2_Domain_0 (375, 2024)

VKDVLNVL-IGVVSATFSLSQATQVFEVKPGVYVSGTSPQNMSSLL
SEVAEYGSHYTRLSHFSLQPVLDSSYNKGLVFQAFTSGLRKYLQYYRACVLSTPPTLSLL
TISFLFKKLGRQLRYLA-ELCGVGTAVPGLSEGGT-----RSSFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKASCEPYTRFIHDWVYSGVFRDVYGEFMIQVNEEYLRCRDKFYWTH
GYVLISKDVEDCVPGFLKHVANDVYVCGK-TINLLKLCCPQHYICWSDIPVPRISVIFSL
DELKEIEKDCAVY-VGRMERLARHSAVSKEEKKLRMEIAKQELIVQARDTASRGLKSLND
RHMSERMVLDAKKREQFQKLKDQFLKDQERRLAAKQEEIDDDFSYARELRAREKRLKALE
EELERRARQDLIDHYSKLSEEAARREQRALWKIQRHKLETARLN-FLLEDQKHIQEMLQN
I-SEGKC-RE--KLDILPS-VHPPGQAG-ASRGDHRA--------QAGQCSENRSEAGDS
EGSPESVQDPLPAGGAWSSGGMEPQ-----TE-SLEGH-ALGT----------RREEPVQ
EVGVSMLPGSSLDLKDFLPRPLPEEPSASPGAPALLEAALQTISMDLPPGGSE------G
QEGSEEQQQQLYDFTTVLRPSATAE-TPSPSRGLPAPR----------------------
------------------------------------------------------------
-------DVPRPRWSF-RSHG---PESSVQSGLPPRDL-IPEPEAPQPCPGPASGRPRWN
IH------------------------------GHKD----------ATTVEPAPPRGSVH
GHVSESSIPLGACTSEVVPSRPRWNLHGHASLSHMR-----------------------M
GDLAVEAETPRPRCSPFGHASWSSLQLGPSEPPPPPKP----PSRHTTPAAA--------
--ASTMQWFLYNRE-LGCSGPDRPPQGDEPSLSSADKPAA----------LAPE----GP
EPILKEMDAPGA-----AEGPEPILK---------------------EMDA--PGAAAGP
-------ESIL-----KEMDAPGAAAGPESI-----------------------------
----LKEVDVPGA---AAGP-EPILKE-VDAPGVAEGPEP----ILKEMDTPG--DEPAV
GPVVTSDESEDLSPNQPL---------GSPVEAETPAAPPTASPGL-AEP--KDGATTCT
REQAYLKALSDQYCLEKYQDSYELMSEPPVSHLLRHIIPRPFSFPLDPP--------DET
SVQLSELLTLPVLMKHSITAPLVSHVSLVNKAVVDYYFVELHLEKHFEALRHFLLMEDGE
FAQSLSDLLFEKLGSGQTPGELLNPLVLNSFLTKALQYSLHGDTKLAANLSFALKYLPDA
FTSNAPDALSCLELRYKVD-WPLNIVITESCLNKYNKIFSFLLQLKHMMWTLKDICFHLK
RTA----LVNHASGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWREFGDKLSAVSN
LEEIHRTHAEYLNKAIF--------------------------R-GLLTEKAAPVMNIIH
SVFSLILKFRVQLISQAWAYDGSRQVAVHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYRDS-
----------------------------

MAGITQLFDDLCEALLPAAP--ARPRQRGVARSRAKQTLKRVAYNALFTSLFQEETQQPQ
PDLPKLPVRNKVLMLSFDLRVGGLGPEADRLEELVEGLEADP--CCPLVELGSALDLLVQ
LAGSGPPRTLRRKRDYFCHNRHAGRNVPYGGYDCCDLRLLEMDVQSLIASEEYSCHSMVQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCGDRFERETRISIFGALVHSRTYDMDVRLDLPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSMTPDVDLWEAALT
YEPSKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQGELQAL-SGGL
LQAPRPLLVKEQELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVVSATFSLCQLSQAFVVERGVHVSGASPESISSIL
SEVAEYGTCYTRLSHFSVQPVLGSSCSRGLVFQAFTSGLRRYLQYYRACVLATPPTLSLL
TIGFLFKKLAC--------L---------------------CSFVQGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSISKEEKELRMEIAKQELIVHAREAASRVLSELSD
RQMSEQMALDARKREQFQRLKEQFVKDQERRLAARQEELEDDFSYAREVRDREKRLTALE
EELDRKARQALVDHYSKLSAEAARREQRALWRIQRHRLESARLR-FFLEDEKRVQEMLKN
V-AEVCQPQE--LLGHLPG-TCSQVTSP----GPEH---------PDRGPTCNSAP----
TELHLAAWDCPGRPSVPA-----------------------TLAEGAEPFSAGLSITDFL
PLGPS------------------AEQPVQTNRALPLEEALQTISSDLPAVS---PGEAHA
TAGTQPAQPQEYDFSTVLRPAAATSPSPGPLQAVEGSLGPEEHAPWEGTHEGTQ-MAL--
-------------------SPPLRHVTSEEGSNQ--------------------------
--------------------------------------------------------PTGQ
------------------------------LHRHVSDASI-RVGENMPDVAPSRPRWNVH
GHVSDASIRVGENMPDVAPSRPRIR----------------------------------V
GENMPDVAPSRPRWNVHGHVSDASIRVGENMLEAEPIP------PWPHQNP---------
------------------------------------------------------------
----------------PSHESQAGSS----------------------LEVQNPALEHGP
----RLPVDTE-----PSICCPKVGSLQNLPSVAS-------------------------
---------------------------------KSSTLGD----SVSEEPGQR--GTQLL
----------GGVPTLSL---------DSQEGTAAPSSPEAA-------A--EVEALRWG
KEQAYVAGLASRYHLEQYPDSYESMSEAPAAHLVRHVLPRAFAFPVDPWVQ---SAVDET
TVQLTELLTLPVLMQRSLTAPLAAHVSLVNKAAVDYFFAELHLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNCILSKALQYSLHGDTPHATNLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITENCLSKYSGIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHTAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFRARLATVGN
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPASGPQGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNSYYQDA-
----------------------------

MASVPQLLDDLCEALLPAAK--AHLGQRRGSRKRAKQSLKKVAYNALFTNLFQDEARKLQ
PDLPRLPVKNRILMLSFDLRVGGLAAEADRLEELVEGLETAP--RGPLAELGSVLDLLVQ
LAGSGPPRVLQRRRDYFLPKEHVGRNVRYGGYDCCHLSGIEADVRSIISGEEELCRDLIR
KTLQVMEAAPGTGLPAF--GLSSYGDPYGDRFERDTRVSLFGALVHSRTADLDVRLDLPP
VPDSADVSGL------AIKVPLSVDQSEDEGFQSAPNLTPDSQSEPGVTPDIDLWEAVLT
YEASRR------RCWEQIG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQGELQVL-GGAL
LQAPQPVLVKESELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DTLNVL-LGVVSATFSLCQPAQAFTVKRGVHVSGASPESVSSLL
SEVAECGTHYARLSDFSLQPVLDSSCSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTALPGTGGGEP-----RAAFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGCRDKSYWTH
GYVLVSKEVEACVPVFLKHVAHDVYVCGK-TINLLKLCCPRHYLCCSDVPVPRISVIFSL
EELKDIEKDCAIY-VGRMERVARHSSLSKEEKELRMEIAKQELIVHAREAASRVLSALSD
RQMSERMALDARKREQFQRLKEQFMRDQERRRAARQEELDDDFSYARELRDRERRLKALE
EQLERKARQALVDHYSKLSAEAARRERKALWRVQRHRLADARRR-FLLEEEKRVQGMLGA
V-SEGKPPE---PLAVLPGALVFQASLP----CPEH---------PDGGGGCGSGP----
SEQPKAARDGPRGPSRLMPQLPESPAEAACGS-GPG--------QDPGLLSVGLSIRDFL
PTAQG------------------AEQPLHTGSALVLEEALQTIGSDLPPPA---PSA---
AVGTGPSGPQEYDFRTILRPAVATSAFPGPLQSTGGGLGSEGQPQWEDTHVQLD-MCVLD
GQV------------ALPHACSPQKTSPQEGS-QAMGQLLRQVS----------EGDVPT
---------------------------------------------GGYASGTAPSRPRWN
VHGHVSDASIKVGENVCDVVPSRPRWN---VHGHVSDASI-KVGENVCDVVPSRPRWNVH
GHVS---------------------------DASIK-----------------------V
GENVCDVVPSRPRWNIHGHVSDASIKVGENVCDVVPSR-----PRWNVHGHVSQSQVTLG
VLSGEAEPIVPWPH----------------------------------------------
-------------QTPPDHGSQSGLS----------------------LGAQRARSVGPP
----ELS----CSWWC--LWAQDGEKGSSLLS--GSRLGPEA-------------RPPPP
PPHLFCPG--RS-------------------EDTVDLPASCRPSSQVRGQGLGVGGESS-
----------AGCPSHPACPFMGNEGSVPGPGVDTQSSPGLGEE----------AAQRWG
MEQAYLAGLAGQYRLEQYPDSYEAMSEPPVARLLHHGLPRAFALPEDSGVQ---PDTDET
AVQLSELLPLPVLMKHSVTAPLAAHVSLVNKAAVDYFFVELHLGAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLSPLVLNSVLSKALQYSLHGDTPHAANLSFALKFLPEA
FAPNAPDVLSCLELRYKVD-WPLNIVVTEGCLSRYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----RMSHVASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLASVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPAMNIIH
SLFSLVLKFRSQLISQPWGLAGGPHGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVSKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRNVNRKRAKQSLKRVAYNALFTNLFQDEMHQLQ
PDLSKLPVRNKILMLSFDLRVGGLGPEADRLEELVEELETAP--CCPLVEVGSVLDLLVQ
LAGSGPPQVLQRKRDYFLNSKHVGRNIPYGGYDCYDLSVFEMDIQSLISREESLCHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCSDRFERDTRVSLFGALVHSRTYDMDVRLDLPP
VPDSADLSGL------AIKVPQSVDQWEDEGFQSASNLTPDSQSEPSMTPDLDLWEAALT
YEPSKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQGELQLL-SGGL
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DALNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESVGSLL
SEVAEYGTHYTRLSHFSLQPVLDSSYNKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGTALPGASGGGP-----RAAFPTGVKLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNHEYLGFRDKFYWTH
GYVLISKEVEDCVPVFLKHIAYDVYVCGK-TINLLKLCCPRHYLCWSDTPVPRISVIFSL
EELKEVERDCAVY-VGRMERVARHSSISKEEKELRMEIAKQELIVHAREAASRVLSALSD
RQMSEQMALDARKREQFQRLKEQFLKDQERRRAARQEELDDDFSYARELRDRERRLRALE
EELERKARQALVDHYSKLSADAARREQRALWRIQRHRLESERLR-FLLEDQKRIQGMLKD
A-SEVPKPQEPP--AILPS-AHSQAVSP----SPEH---------PDGGQGCDSRL----
REQHLAAQDYHSQPSVPTPQLLEAAAVGAGGT-GS-------------------------
QQVAG------------------AEQPVQTGEVPLLEEVLQTISSDLPSAA---LGETPV
AASTQPSGPQEYDFSTILRPAVATAPAPGPFLAEEGCACSSEQQVWGDTCMQLD-ARVPD
TQV------------ALPQPQPPSHVSP-EGSSWPTEQLLGHLS----------GAAVPT
---------------------------------------------EGCAPGTAPSRPQWN
IHGHASDASIRVGENVSDVAPTRPRWN---IHGHASDANI-RVGENVSDVAPSQPRWNIH
GHASDANIRVGENVSDVAPTQPRWNIHGHASDANIR-----------------------V
GENVSDVAPSQPRWNVHGHASDANIRVGENVSDVAPSQ-----PRWNVHGHVSQSHMMLG
PLSPEAEPNVPTPH----------------------------------------------
-------------GSPPGQLSQAGLH----------------------LGAQSPALECGS
----QSPVEVPSAAQPEP------------------------------------------
-------------------------------GPAHC-----------PSAGPGRSGGAE-
----------DTSPRRPL---------GPQVRAGASRGPG--------------------
------------------------------------------------------------
-------------------PGLGVHISLVNKAAVDYFFVELHLEAHCEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQYSLHGDTPHAANLSFALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNMVITESCLGKYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----LVSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLAAVRD
LEDIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SVFSLVLKFRSQLMAQAWGPAGGPRGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDT-
----------------------------

------------------------------------------------------------
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----------------------------------------GHVS----------ESSVPT
---------------------------------------------GGYASRIAPSRPQWN
IHGHVSDASIRVGENVWDMTPSRPRWN---VHGHVSDASI-RVGENVWDVVPSRPRWNVH
GH----------------------------------------------------------
-------------------VSDASVRVGENVWDVAPSR-----PRWNVHGHVSQSHMMLG
ALPEEAQIDVPRSH----------------------------------------------
-------------QNSPDHVSQSGLS----------------------LEEQSPTQDQEP
----QLPTETASGSSCALAAASGCEEESGLKASLPAGVVPGALGDGTPE-----------
------------------------------------------------EPGPRRSGDTE-
----------DVSP

PF04130 // ENSGT00850000132278_2_Domain_2 (1635, 2024)

SHPP---------GSKEGADARSSPGLGEEA--------VVPARWD
KEQAYLASLAAQYRLEQYPDSYEALSEPPVARLLHHGLPRAFALSEDPRGP---SDADET
TVQLSELLPLPVLLKRSLTAPLAAHVSLVNKAAVDYFFVELHLEAHFEALRHFLLMEDGE
FAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQYSLHGDTPHAANLSFALKSLPEA
FAPNAPDVLSCLELRYKVD-WPLNIVITESCLSRYSGIFSFLLQLKLMMWTLKDVCFHLK
RTA----LVSHVASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLILKFRSQLISQPWGPASGPRGAEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAAK--THLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQ
PDMSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAP--CCQLLEVGSVLDLLVQ
LAGSGPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMHVQSLISREECLCHSMIQ
ETLEVMEAAPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPP
LPDNADVSGL------AIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEASKR------RCWERVG-CPP-GHREEPYLTEAGRDAFDK-FCRLRQGELQLL-AGGV
LQAPQPVLVKECELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DVLNVL-IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLL
SEVAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLL
TIGFLFKKLAWQLN--G-GLCGSGVGLAGR---WR-----VCPAPWGVKLLSYLYQE---
----AHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKSYWTH
GYVLISKEVEDCVPVFLKHIAHDVYVCGK-TINLLKLCCPRHYLCWSDVPVPRISVIFSL
EELKEIEKDCAVY-VGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------XXX--------XX-XX-XX--
---XXXXX---XXXXXX------X---XXXXXXXXX-------X-X---X-XXXXXXXXX
-----X------XXXX------XXXXXX----X-------------XXXXXXXX------
X---XXXX-----------------------X-XXXXX-XX----X-------XXXXXX-
-XXXX------------------XXXX---XX------XXXXX-XX--------------
XXX-XXXXXXXXXXXXX-----------------------------XXXXXXXX-XXXX-
XXXXXXXXXXXXXXXXX----------------------XXXXXXX---XX-XXXXXX--
---------X--XX-XXXXXX---XXXXXXX--------------XXXXXXXX---XXXX
XX----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------XXXXXX----------------------XXXX-----XXVLSRSA
LPN-----TPRPQQSPPGHMSQSALC----------------------LGAQSTVLDRGP
----RLPVEVG-----PSLSSPSSGCGEES---------------------ISV------
-----------GENVSDVAPTQPW------WPNT---PGD----GVSEELGPGRSGD---
--------TEDVSPNRPL---------NSQEDTAAQSSPGAGEEE----E--AVAAEAQG
GEQNYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQ---SAADET
AVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGE
FAQSLSDLARHVLG---TPGDLLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEV
FAPNAPDVLSCLELRYKVD-WPLNIVITEGCLSKYSGVFSFLLQLKLMMWALKDICFHLK
RTA----LLSHMASSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFKARLATVGD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPAGGPRGAEHPNFALMQQSYNTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------

MASITQLFDDLCEALLPAVQ--PRPGQRSVDRRRAKQGLKRVAYNALFTNLFLEDARPLR
PDLSKLPVRNKVLMLSFDLRVGGLGPEADRLEELVEGLEAAS--CCPLLEVGSVLKLLVQ
LAGSGPPQILRRKRDYFFNNKHAGRNVPYSGYDCCGLSGSEMDVQSLISREEYLSHSMIQ
ETLQVMEAAPGTGLPTV--GLFSFGDPCGDRFERDTRVSLFGAFVHSRTYDMDVRLDFPP
VPDSADLSGL------AIKVPQSMDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALT
YEVSKQ------RCWERIG-CPP-GHREEPYLTEAGRDAFDR-FCRLRQEELQVL-SGGL
LQAPRPVLVTEQELVK

PF04130 // ENSGT00850000132278_2_Domain_0 (377, 2024)

DSLNVL-LGVASATFSLCQPAQAFVVAQGVHVSGASPESISSIL
SEVAAYGTCYVRLSCFSLQPALGSCCGRGLVFQAFTSGLRRYLQYYGACVLATPPTLSLL
TIGFLFKKLGRQLRYLA-ELCGVGAILPGAGGGEP-----RASFPTGVRLLSYLYQEALD
NCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDVYGEFMIQVNDEYLGCRDKSYWTH
GYVLISKDVEDCVPVFLRHVAHDVYVCGK-TINLLKLCCPQHYLCWSDIPVPRISVIFSL
EELKEVEKDCAVY-VGRMERVAHHSSISKEEKELRMEIAKQELIAHAREAASRVLRELSD
RQTSEQMALDARKREQFQQLKEQFVKDQERRLVARQEELDEDFSYARELRDRERRLQALE
EELEKKARCGCVAGCLG-------------------------------------------
-------------------------------------------------------M----
----------------------------------------------AQQFQSGLVLVM--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------V---SS---FWAHAELDSI-RVGENVSDVAASRPRWNIH
GHVSDASIRVGENVSDVAASRLRWNTHGHVSDASIR-----------------------V
GENVSDVAASRPRWNLHGHVSDASIRVGENVSDVAVSR-----PRWNIHGHVSDSSIQIG
ASVSDVASSQPCWDGCTT---------------------------QPL--------FLEA
-----ESNLPRLPYSLLGQGSQLGSP-----------------------EVESPALECVP
----TLSAEVE-----PATCFPGAGS-----------------------------WEAGG
LRASPS------------------------AVAEPGTLGD----SVSE------NGNTV-
----------DLSPHQPP---------DSQGDTATPGQPGPGEEA--VEAEAEAQARRWG
EEQAYLASLARLYPLEQYPDSYEAMLESPVTHLVHHVLPRAFTFPMDLRAQ---PAVDET
AVQLSELLTLPVLMKRSLTAPLAAHVSLVNKAAVDYFFVELHLESHFEALRHFLLMEDGE
FAQSLSDLLFEKLAAGQSPGELLSPLALNCVLNKALQCSLHGDSPRAAGLSFALKHLPEV
FAPNTPDVLSCLELRYKVD-WPLNIVITESCLSKYSAIFSFLLQLKLMMWTLKDICFHLK
RTA----LVSHSAGSVQFRQLQLFKHEMQHFVKVTQGYIANQILHVSWCEFRARLATVSD
LEEIQRAHAEYLHKAVF--------------------------R-GLLTEKAAPVMNIIH
SIFSLVLKFRSQLISQAWGPASSPQGTEHPNFALMQQSYSTFKYYSHFL-----------
---------------------------FKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA-
----------------------------