ENSGT00840000129843 : Linker Region Query Results

-MLSPTFVLWEVGYPLYIYG--SIFI-VIVIIWQVKRS-HHELSSEPKRSCC--------
-------------RCH--QKVRQRARDA--ASTARRR-SREEAEKPQKLLSIIKSQGWLP
LERSVRRILCADPCCQICNSVALEIQQLLVGENNQISLTLS------GPL------QGSS
CLEMLSTSSMSLDQ-SLE------------------------------------------
--FHSWHTRELSLS-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLRGPNTIASSRIEKPRAPLNQEEM-TQS--NP--SLVQGNQG-Q
HHLNSQVSLLSL-NPET-LNRMHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPVSFNLK--NTPQVSLHRFETISL
QTWC-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQT------PNPM-ALALPSPALKA
-LSGP-HPQSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKIE
NVPKPPL-------KDPFLFN---ELSF--PQLLPKTSPQSAPPSSPLSPNWMSPSDHQR
AQ-I--NV----PFLTLAEYEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCGKAQSPETTT-------ASQTGKSISVLTRELLFFPEHARKLLEFHI-QKQLIRHRW
GLPQKIQQSIQLLLTSTDQQTVSS SSTA--LANVSIPQPVALEANGACDVL-SPIAAPVS
IPRPHLLT QVKAILQSHIDSKCGQIHQGKIPACVHRSWDCRISGVLA--VAPFPCIPESQ
F-LELQTAS--DPDLHHKVMPW--MPTALDQQ---QQALPGTVTEHPKLLRVLSVEAIEK
LET-TLRHKHLAFLSGLPAL--YYVALPRALAPAVT---SQSV-ITEMEPS-PVEI--PA
E-PLIQMVSFEEQCIS-----------------------LGPCPQGNNESCTDV--AKEF
QPAVPVKGTME-TLPLESQT-----HPTSPHSLQTHILTKLNFHLRKKVLEI--QWGIPI
R--A-RKSREQTVAA-PENISTQKSLESLNHQGETL-LQELPIPP-DTLPAPNPEGVHL-
-KEQLANDLKA----VQQNQKQSNSKAVPQG-SAH----SVSKI------SQPSGDMTE-
-AHMPCVQVEANVNKPSLEEPCGPEPQS-----PSKSKDPAHVPMLAGNREDPEETKAAR
DHREGDAGFGRSSTREERRPAEDQRPAGMLPNKTPRGSWRWSR-----SF-HLADPCQHS
PQHHPQLKLPQLPP-RVPGEKESE-KDLQDSQTKLTVILEPATIPENAQTVLPQASQGQP
FLSQPTQAKPLQGQTLQGQVLH--GLVMPVHAQKKPS-LTESSFRNKIKCFLQHINPKTK
GKGHEDS-MFSAAAKVAKTRKENVAKSLAPAKSPVGRSKTEK-PTGCSKAQ----SRPAQ
KLVGPAFLDGPQSLDDKLRLHSR--QPGSASALGY-PRHCPRHCPREACANKPGHPT---
-----------------------------

-MLSPTFVPWDVGYPLYTYG--SICI-IALIIWQMKKS-RQKLRLEPNRSCY--------
-------------RCH--RRIKQRSRER--TSRARRT-SQKEAEKLQELLSVMKSQGWLP
QVEGVRRLLCTDPCCQICNDVALEIQQLLEGENNQNSPTLL------GQT------QGSS
HLDTLSMSGESFEP-SLE------------------------------------------
--LGSQSSRAVSPA-FITPIPTQLMDQKPLTQSAD--------QSTGA----VNVQD--C
WTDYLQQGQKFQVSDVSEVMGLLPPSSLKEPGISPNQQETR-KK--KS--QFVLENQ-E-
-------------ASEV--GLGNKMKI-------FLH-WINPEMKGQRPEESILLPKAET
LAKAKTKNVEKSLSLPKDPVGGANS-EKTTEDPEAQLPPPDEE----GLTFCDAPNIE--
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-MLSTMCFLWDTECPLYVYF--CFFI-IVLIVWQVRQN-YQGLKCENRRSCC--------
-------------RRH--QKVRQRAKDA--ASRARRL-SREEDEKPCELLSIMKSQSWVP
KQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALL------GLP------QRAA
CLEM-PISSESFEW-NQD------------------------------------------
--FYSRYSTNSPVV-PGNQTLTQLTEEL------T--------ESTNA----DGVLL--C
WTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTV-HS--NL--NYIQQLQD-H
EALNSQIPFQTL-TPQL-T-VTHPMAV--SIVTDAPQPFLSPEVLRL--LEIHVKKLMHF
QRWGLPRRVEES---LKQFMPNPPVYLPPEHN---QPVSFILN--TSSQDCVHRFEGISP
ETWY-SYMDGQPIQTFWVSEWSSGDQGQ---RLSCKPI------PSPV-EKPLLTPDYEL
-LHDL-CLSPEGQVDGSQSNL--QKKFTQLFCGLPSM----HSESLGSTFLCTQGVSKNT
--LKPPY-------KEPHFLK---VSPP-------IPLPEAAPPPSSTSPNE-SLDEPQR
AQIG--GV----PFLTLSECKTLEWHLLQRQL--QLQWGLPAVIARPPRVQSH--TQYKH
KPWNKAKPRETLK-------FFGPGKPFSALTRELFFIPQHARRLLEFHL-QKRLIHLRW
GLPQRIQRSINMLLSSTDLQSLPCG--GSRLPNVSISQPGKPEAYGSGDTF-LPTAGKGT
TPMPHLFAKAQEMLKSH-DTKCEQIREGKVPACVQSAWKGRIPGDLAA-GTLFPNIPQGQ
P-LELQAEN--NPDLHQEAVSW--KPMDLDQE---AQAFSGVFIEHCRRPQALSEETIKK
LET-TLRHKYLAFLSGLQAL--YCMAPTKATSPT-V---DQSV-ITTM-PW-SVKS--PQ
K-PLSQKSPLEALCLSG----------------------LEPCTQDDKETSANI--AEEF
QHGAQGHGRTE-KVPPERQP-----LLNRPYSLDTEIMERVSFYLKRKALDI--KLGISL
K--E-SVFQEPTATD-LESESVQEPLGSPR--ESTL-LQGPPTLC-HVPVAPDPDKVCL-
--KQPATAVQV----VFQEQNQPSSRAVPHR-SAR----QGSQ---------VHRNMME-
-AQVHYVQMGTGGEMLNLGEPFSTESQS-----PGKSK-SGYVPTVAGKRKIPGKPKVVG
DLGEGDAGLGFSLVSLKTRQDGEQ--EKRLLHRQLQGSSLQAQ-----TF-HLEGACPHS
PQESPELQFADPPP-EVFMETDSE-QDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLP
FPRSPTQRKPSQGQPGPGHVPP--GHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMK
SKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPED-FRG-PKAQ---FS----
--VVGPCLTPSYILDSKFWPRPR--RVGSVSVLGH-SYHCPRHCPRLAYANQQRNPP---
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVQQKSGNR--TSTARRT-SQEEAKKLRKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQISLTSQ------GPS------QGSS
GLEALSTSNVSFEH-SQD------------------------------------------
--PGSQKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNVEKSPTVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAPQCLNN
LL----------------------------------------------------------
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-MLSPTFILWDVGYPFYTYG--SIII-IALIIWQVKKN-QQDVKLGPKRSCC--------
-------------RRH--QKVKQRAKEK--TPRVT-----------NDCHASLPSHGWLP
QEGSVRRLLCADPCCQICNSVALEIQQLISCETTLTTATSS------GPS------QGSS
CLELLSIS--SLSF-DQE------------------------------------------
----SLPFKQLSLP-SATRTVSQVTNQKSVTQSAAKSATKPATKSASA----ISIRQ--Y
WAGHQQLRQECRGSELPLDAGAVSFVSLEKPRIPVNQHVKK-KS--KS--EGILKKQ-E-
-------------AVEA--DLGNKLKH-------FTH-GINPDTKGQGHKECILCCKDEK
AAKTKRK----------------KL-EKEE-------------------GFFDALQCLDT
TVRAVW------SVLFP-APLASGS------SKGSPLLTRATQPENPSHVSICTSA----
--KGT-CLPQES-----------TQSRKKELRGSQTS-------------------ASS-
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-MLSSACSLWDISSPLCTYS--SIFI-IFLIAWQVKRS-YQGLKLEPKKSCC--------
-------------RRH--RKVRQRARDA--ATQARRL-SQEEAEKPWNLLSIMKSQSWLP
TEGNVRQLLCVDPCCQICDSATLEIQQLLESDKSQISPALL------GLP------QDSS
CLDMLPISSVPFEG-NME------------------------------------------
--LHSRHSRHLSLA-SETPTLAQLTEHL------T--------QSINA----VSVQE--C
WADDLQLDQKFDLADMPIISETVVSSRLEEPVVLMIEEKIM-QS--QP--KVVQESQD-Q
HPLKSSVSLLSL-NPEI-TNLTHSVSLHMDSVLSSHVPLLSPKVRRL--LELHVKKWIHF
QKWGLPRRVEES---LRQLMPDPALFCRSRKH----MLSSVLS--SASEVPMNKAGTISQ
-------------HTCWVSEWSIINSKQ---RMHWHQI------YEY-----LPSHE-EH
-LSAS-SPPTRAQDDDSGSNLPENEYYSQLFCGLPSL----HSESLDVTSLSIHSVSKNK
NVPKSSS-------TDPRHTK---ELSL---PFLPQTPCKSALPSSLASPDVKTSHEHEE
LQ-F--LV----PFLTLAECEALERHVLERQV--KLQWGLSGVFLRNQYRQRH--TLCE-
-PHGKA---KTVK-------ASWPRNAFSYPTRKFS-FPEHVRRLLEFHL-QKQLIHIRW
GLPQRIQRSIHLLLSSANEHALSCSRSR-ALSSVSIPKPGSPEADGSGDRF-ASAVDKGP
ILMPHLFVQAKAMLKSHFDSKCDQIHQGKVPAQVWSSWECKIT------TVPFSWIPQSQ
H-LKLYPESKSNA---------------D-QE---KKALSGTLIEHCKRPQALSKETIKK
LET-TLQHKYLAFLSGLPAL--YCVALSRPTSPAVT---SQHR-TTEMMSL-PVKS--PP
K-ARTSSK---GP--------------------------FESCTQDDNKASANI--TEEL
QPEVQVEGKTD-CQ-----T-----HD--IHLLNTHILAKLNFHLKRKVLAM--QFGISE
K--E-REYKELAIVD-LESESIQEFLRSLSIPESTE-LQKLPDSG-DLPPAPDAGTDHL-
-KKQPATEVQA----VCHQQKKPSSEAVPQG-SVE----WDSKV------SQL-RNVTE-
-AQVPCVQMETSGEKPNLEEP-------------------------------G-KPKAVG
DLGEGDTGLGLSPTSEGTHRDGDQEPEEGPVHGTPEGSSQHSH-----SF-HPEDPCPPS
PQNTPELEFPDPPP-EVFMEREPE-LDTQDSQTKANV--PQ--------PVASRASQGIP
FPRPLIQGKPFRVQTRQDRISRGQGRVMPTSPQASP-SLPEAGLKNKVKSFLQSINPKIK
GKTHVEPM-VSTPATVAKTSKENVGKGLPQAKSPTQKAKAEN-CRG-PKAQ---ST-PAE
KSVIASFLTAPHILDSKLRPNPG--QHGSVSVSGQ-PRHCPRHCPRLAYATQHRN-----
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SIFI-IILIIWQVKRSHH-ELSSEPKRSCC--------
-------------RCH--QKVRQRARGA--ASTVRRR-SQEEAEKPQKLLSIIKSQGWLP
PEGSVRRILCADPCCQICNSVALEIQQLLAGENNQISLTLS------GPL------QGSS
CLEMLSMSSMSLDE-CLE------------------------------------------
--FRSWHTRELSLA-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLRGPNTMASLRFEEPRAPLNQ-EM-MQS--NP--SLVQGNQG-Q
HHLNSQDSLLSP-NPET-LNPTHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWVHF
QRWGLPRRVEES---LRQLMPNPPLYYQSGND---QPVSFNLN--NISQVSLRGFETISL
QTWC-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPAFKA
-LSSP-HSLSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKNG
KVPKPPM-------KDPFLFN---KLSF--PQLLPKTSPQSAPHSSPLSPNWVSPSDHQQ
AQ-I--NV----PFLTLAECEALEWHLLQRQL--QLQWGWPAALQRSQHTQCF--MQHE-
-PCCKAQSPETMT-------TSQPGKSISVLTRELLFFPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIHLLLTSTNQQTVSYSSTA--LANVSIPQPVALEANGACDVL-SPTVAPVS
IPMPHLLTQAKAILQNHMDSKCGQIHQGKIPACVHRSRDCRIPGVLA--VAPLPCIPESQ
V-LELQAAS--DPDLHHKVMPW--MPTTLDQQ---QQFLPGTVTQHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRALAPAVT---SQSV-ITEMVPA-PVEI--PA
E-PLTQMVSFEEQCIS-----------------------LGPCPQGNNETCTDV--AKEF
QSVVPVKGTTE-TLPLESQT-----QPASPHSLQTHILTKLNFHLRKKALEI--QWGIPI
K--A-RESREQTAAA-PENISTQKSLENLNHQGEAL-LQELPIPP-DTLPAPNPEWVHL-
-KEQLANDLKA----VQQNQKQSSSKAVPHG-SAH----WVSKI------SQPSGDMTE-
-THMLCVRVEASVNKPSTEEPWGPEPQS-----PDKSKDPAHVPMLAGKREDPEETKAAR
DHREGDEGFGHSSTRGERCPAEDQRPAGMLPNQTPRGFWRWSR-----SF-HLADPCQHS
SQHHPQLKLPQLPP-RFPGEKESD-NDLQDNQTELNVILESATIPENAQTVVPRASQSQP
FLSQPTQCKPLQGQTLQGQVLH--GQVMPAHAQKKPS-LPESSLRNKIKSFLQRINPKTK
GKGHEDS-MFSA-AKVAKTRKENVVKSLAPAKSPVGRSKTEK-PTGYSKAQ----SCPSE
KLVGPAFLDGPQSLDNKLWLHSR--QAGSASAPGH-PRHCPRHCPREACATKPGYPP---
-----------------------------

-MLSPTFLLWDVGYPLYTYG--SIFI-IILIIWQVKRS-HHELKLEPKRSCC--------
-------------QRH--RKVRQRDREA--ASRARRL-SQEEAEKPRNLLSVMKSQSWLP
QEGSVRRILCADSSCQTCNAVALEVQELLAGENNQKSPLSS------EPP------QGSS
CLEVLSVSSVPLKP-NLE------------------------------------------
--HPSWQPKELSLA-CLNPTLSQLMDQKSLTQSAS--------QSTNA----VPVQD--Y
WADHLQLGQKFQVSDVLKGPESMVSSKLQEPGVPVNQQEMMMQS--NP--NVVQGNLD-Q
YHLKYQDSLLSL-NPEI-ANMTYSMDLNM--VLPAHLPFFSPKVLRF--LEVHVKKWMHF
QRWGLPRRVEES---MRQLMPNPPLCYQSEDD---QPVPVILN--NTSQVSVHRFEAISH
ETWC-SCMAGQPIQTFWVSEWPMMNPEE---RKYYQQI------PSPM-APALSSPALKV
-LSGL-YSLPAGQVNDSGNHL--QEKYSQLFCGLPSL----HSESLVATFLGSHGLSKKR
NMSKPKL-------KGSFLFK---DLPF--HPLLPKTPPLSAPPSSPPSPNWVSPSDQQG
TQ-I--NT----PILTLAECEALEWHLLQRQL--QLQWGLPAVVQRPRHAQSP--MQHE-
-PCDKAQAPGTVK-------TSCSGKPISVLSRELLFLPDHARRLLEFHL-QKQLIHHRW
GLPQKIQQSIQLLLSSTDQQTLSWSSTA--LANMSIPQPTALEANGNSAVF-SPITGPAS
IAMPHLFAQAKAILQSHIDSKCGQIHQGKVPACVHSSWDYRIPGGLK--VIPFPCIPESQ
P-LELRAAS--DPDLHHKVMPW--MPKALDQQ---QHALPGTVTEYHQLPQALSEDTKEK
LET-TLWHKYLAFLSGLPAL--YYVALSRAMAPAVT---SKPV-ITEMVPE-PIAV--PE
E-PLTEIISFEEECSS-----------------------LETCFQDNNGTRADV--AEEF
QSTVQVEGMTEETVSQESQE-----HPASPFTSKTHVLAKLNFHLKKKVLET--QLGIPI
R--A-RESMQQTAVV-PEDTSTQDSLGRMNNQGETL-LQELPIPP-DTPHAPDLDCAHI-
-KEQLAIKLKT----VQQSHEQLSSKAVPQG-SDH----WVSSD------PQPSGDVTE-
-AQVLCVQVEASVNNTSLEEPWSPEPQS-----PGKSRDSVQVPILAEKIEDPVKPKAAG
DHGEGDAGFSLSSIREGRHPVEDQRPAEMLLNKTSQGSCRQSH-----SL-HLVEPCPHS
PQHHPLPKLPDLLP-GVPGGKASE-DALQDSQTKLNVTLEPAMIPQNAQAVVPQASQGQP
FLSQLIQGKPLQGQTLQGQVLH--GQEMPAHTHKWPS-LPESSLRNKIKSFLHRINPKTK
GKGHEES-MFSTAEKVAKTRKENVEKSLAPAKSHGGRTKTEK-PIGHSKAR----SPRTE
KPVGLAFFGDPHSPGNNLRLRSR--QPVSASVLSH-PHHCPRHCPRGAYATQAGCPPS--
-----------------------------

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----------------------------------------------------MRSQGWLP
QEGSVRQLLCEDPCCQTCNSMALEIQQVLADENTLVSPTSG------EPA------QGSS
CLEVLSTPKVSFQQ-SME------------------------------------------
--HRSPHSKNLSLP-SANLT----VSQKSLAQSVA--------RSPGT----AGIHD--Y
WAEHLKQRQGFQMPEVPRGPETMLSSRFEEPRVSVNLQEI-IQS--HP--NLVYGNQG-Q
QPLNSQVSLLTL-NREI-TALTHPMALNMVTVLPAHLPFLCPEVLRL--LEVHVRRLMHF
QRWGLPRRVEES---LRQLMPNPPLFCHPVHN---QPVSFIQN--DISQFSVEKFGTISY
QNWG-SCIAGQPTQAFWVSEWSIMDPEQ---RHYYQKI------PDHT-TLASPYVALKE
-SSGL-YLMPGQQASDSEGPV--QSKYSQLFCGLPSL----HSESLVDTFLGYQGLSMNE
SMSKHSL-------KYPFLFK---ELSC--FPLVPKTLPQSALPSSPSSPNWTAPPEHQQ
AQ-I--SS----PLLTLDECKALEWHLLQRQL--QLQWEFPDVFQRDQHTESP--MQCK-
-PSDQAQSSETVK-------TSWPGQPVSTITKEI-FFPEQARRLLEFHL-QRQLVPNHS
SLPWKNQRSLQLPLPPAGQQTLSWSSKA--LDNVNVPQPTALEGTGVGDPL-PAIKDPAS
VPMLHVTDQAKATLQSHVDSKCKEIHQGKVPVCIHGSCEFKIPGGLQ--VAPFTCIPESK
P-LELQAVD--DLDKQQEVTPW--MPTALDQQ---QQASSDALIKHPKLPWALSQGAIEK
LKT-TLQHKYLAFLSGLPAP--YYVALSRATAPAIT---SPAM-KTEMVPR-PIQF--PT
E-PPTQVPSPEEQGLS-----------------------PGPGFQDGSEACADA--AGEF
QAEVQIEGIIK-MVPQESQT-----GPARPCSLREPILTKLNFHLRKKILEI--QLGIPL
K--A-RESREQTVAM-PKNMCPQESPGNLDNQGKLP-LQDLPIPP-DTPRSPDPEWLHL-
-TEELATELKT----AHQEQKQHHSGAAHRE-SVH----WAAQI------SRSSGDMTGA
KAQVLCAQLEASVNNPSLEEPWSSEPHR-----PDKSKDSAQVPTLAEKRKKPGKPKSAG
DRGEGDASFILSSTREKSHSTEAQRPEGVLLNRKPFSFCCQRR-----HF-HLDAPCQHS
PEHHPQLKLPELPP-GVPDGKDSEKNDLRASQAKLNVILKPARVPESAQPVVPQVSQGQS
FLGQLTPGNPLWGHTLQSQMLQ--GPVMPGYTHQRPS-LPDSGFRNKMKSFLHCINLKTK
GKGHKES-TSPTSEKMANTRKVNAAKSLAPAKSPKERPKTEK-TRGVLKAQ----LPPPE
KQMGLVFTDIPRSLDSKLWQHSHSHQLRSASVLST-PHHCPRHCPQVVCATQPGNPP---
-----------------------------

-MLSSTGFLWDTECSSYVYF--YIFI-IVLVVWQVRQN-YRGLKCEHKRSCC--------
-------------RRH--QKVRQRARDA--ASRARRL-SREEAEKPWELLSIMKSQSWIP
KEGSVRQLLCLDPGCQICEAATLEIRQLLQSEKNQLSPALL------RLP------QGSV
CLEMLPISSESFQW-SEE------------------------------------------
--LYSGPSTNFPVA-PGNQTLTHLTEQF------T--------QSTSA----DGVQI--C
WTDHLQVGQDFHPTDMPMAPETVMSSRLEESAVFANEEDMV-DS--NL--NYIQQLQE-H
EALDSQFPFQTL-NPQI-THATHPMSV--SIVTDVPQPFLSPEVLRL--LELHVKKLMHF
QRWGLPRRVEES---LKQLMPNPPMYFQPEHN---QPVPFILN--TNSQDYVHRFGGMSP
QTWY-SYMDRQPIQTFWVSEWSSLD--Q---RLPCKPI------PSPM-EKPLPIPDYEL
LVRDL-CLLPKAQADDFQSNL--QKKFTQLFFGLPSM----HSESLGSTFLCTQGVSKDT
--FKPSY-------KDPPFLK---ELPL-------FPLPKAALPPSSTSPNE-SLCEHQQ
RAQI--GV----PFLTLSECKTLEWHLLQRQL--QLQWGLPAVIPGSPYTQSH--TQYKL
--CNKAKPCETLK-------ASRPRKSFSVLTRELFFIPRHARRLLEFHL-QKQLIHQRW
GLPQRIQHSIHMLLSSPDQQSLSCMGG--SLPDVSISQPENPEVDRSGGVF-SSTAGKGS
IPMPHLFAEAKAILKSHVHTKCEQIHKCKFPACVQSSRDHRIPGNMAA-GTLFPNIPQGQ
P-LELQAEN--NPDLHQEVVPW--KQMDLDQD---TQAFSGAFIEHCRRPQALSEETIKK
LET-TLRHKYLAFLSGLQAL--YCVAPTRAISPT-V---DQFV-ITNM-PR-PVKS--PQ
K-PVRQKSPSEGPCLSG----------------------LVSGPQDDNETSANI--EEEL
QPGVQMDGRTE-KVPPEREP-----LLNRPYSFNTEIMEKLNFHLKKKVLEI--KLGLPL
K--A-NALQESSAAD-PESDSIQESLGSPCLSESTL-FQEQPASG-DLPPAPDPNEVHL-
--ELPATAVPA----AFQEQERPSSRAVPHS-SAP----QGPRP------LYFYRNMIE-
-AQVHYVQMGTGEETPNLGEPFSTESQS-----SRKSKSSGHVPTMTGR--NLGKPKAAG
DLGEGDAGLLLSLVSQKPHQDGELEVEKKTLHRTPQGSSQQGH-----NF-QPEGVCPHS
PRESPELEFPAPPP-EIFMEIDSE-QDTEDSQIEDSIVLEAARIAEVPHSEVSQASQGLP
SPCSPIQRKPFQAQPCPGHFSP--GRMMPASPNTRPSHLPEAGLKNKMKFFLHSINPKTK
SRTYTEPPVVFTPGKVAKTSKENVERGLLRTKSPTKKTRSED-FRG-PKAQ---SL-SSE
KPVIAPYLTPSYILDSKFWPRSR--QLGPVSVLGS-SHYCPRHCPRLAYATQQRNPP---
-----------------------------

--------------------------------YLLKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVKQKSRDT--TSKARRT-SQEEAEKLWKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNAMALDIQQLLASENSLISLTSL------GPS------QGSS
CLEALSTSSASFEQ-SQD------------------------------------------
--LGSEKSKEHSLA-SVTTTRSQLTDQKSLTQSAT--------QSAGA----DSIQD--S
WSDHFQRGQGSQVPAVSQGMGSLS-SNFEKHGIPLSQQESE-KN--NS--KFVLEHQ-E-
-------------APEV--RLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAMR
VTQDRTENTEKSPTVTKDHVWGATT-EKTTEDPEAQPPSTEEE----GLIFRDAP-----
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-MLSPTFILWDVGYPLYAYG--SIII-IALIIWQVKKS-HQEFRLGPNRRRP--------
-------------CIL--SFL--VTLSP--GFSARRL-SWEEAEKPWELLSVMKSQGWLP
KEGSVRRLLCADPSCPICNAVALEIQQLLAA-----------------------------
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--------------AET--CLGNKMKL-------FPH-WINPEVKGQGHKESI-LSKDET
VAKTMTKKVEKSPPSTKHPVRGAKW-EKKT----------EEE----GITFFDVPQSQDN
ELKQQP---LQSRCSWL-LGLPHNN------SKHCPQLTGDTQPEHPSQISALTSA----
--EGT-GLYKEN-----------TQSRKKEFIGSQSS-------------------AFP-
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----------------------------------------------------MKSQSWVP
KQGNVRQLLCLDPSCQICEAATEEIQQLVQSEKSQLSPAFL------GLN------QGSA
HSAHLEMLPMSFEQ-NME------------------------------------------
--LCSRHTRPHPRV-PGNQTLTQLTGHL------T--------QLTNT----FGVQE--C
WTDRLQLDQNFHLANMPVVSETVTSSRLKEPMVLMIEETIV-QS--KA--KLDQESQD-L
HHVKSSVSLLSL-DP----NLTHTMSLHM DSMLSSHLPLLSPKVRGL--LELHVKKWIHF
QKWGLPRRVEES---LRQLMPDPTLFRRSREN----PSSCTLS--SSSKVTEDRTGIVSH
KTSS-LYSAGQPVQTFWVSKWPVINLQQ---GRPWHQI------HTC-----LPSHEGEH
-LRNF-YPLPRAKANDSGDNL-QSEYYSQLFCGLPSL----HSESLDVTSLSSQGICKKK
DMSKPST--------DAQPSG---VLSG---LFLPKTPCKSAFPSSPTSLNGKTPCEREG
AQ-I--TV----PFLSLAECEALERHLLKKQL-SKLQWGLPALLLQNQ---RR--MPCE-
-ALSEA---KTVK-------TSLARKPFLHPTRD-I-FPEHAGRLLEFHL-QKQLIHLRW
GLPQRIQRCMNMLLSSTDPQSLPCGS-S-SLTNVSISQPGKPEADGPGDMF-LLTAGKGT
IPMPHLFAKTREMLKSHVDSKCEQIQEGKVPAQVWKSWECKIPGSLAT-VAPFPWIPQGQ
C-RKLQAESKSDPDLLHKVVPW--KPKTLSQE---TQTLSGTLFEHCKKPQSLPKETIKK
LET-TLHHKYLAFLSGLPAL--YCVALSRPASPAVT---SQPR-LREKMPK-AVKS--PS
R-ALTQIT----P--------------------------LESCTQDDSGVSADT--AEEF
QPGAEADGRTE-KVPAESQP-----PPCRPYPINTHILAKLNFHLKKKILAM--QFGISE
K--EKREHKELGTAD-LESESIQEFLRSLHTSESTL-LQEQPVAC-PSLPAPNAKGVHP-
-KKQPASAVQD----VCQAQRPPPSKAVPHS-SAQ----QSSKA------SHSQRD----
-KIQVCVDTEAGGKRFNLE-----------------------------------KSKVVG
DLGEGDAGLGFSLVGQKTRQDEEQ--EKRLLHRPLQGSSQQGH-----TF-HLEDACPHS
PWVSLCSPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSTMCFLWDTECPLYVYF--CIFI-IVLIVWQVCQN-YQGLKCENRRSCC--------
-------------RRH--QKVRQRAKDA--ASRARGL-SREEDEKPCELLSIMKSQSWVP
KQGNVRQLLCLDPSCQICEATTLEIRQLLQSEKSQISPALL------GLP------QSPA
CLEM-PISSESFEW-NQD------------------------------------------
--FYSRYSTNSPVV-PGNQTLTQLTEEL------T--------GSINA----DGAPL--C
WTDPLQVGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTV-HS--NL--NYIQQLQD-H
EALNSQVPFQTL-TPQL-T-VTHPMAV--SIVTDAPQPFLSPEVLRL--LEIHVKKLMHF
QRWGLPRRVEES---LKQFMPNPPVYLRPEHN---QPVSFILN--TSSQDCVHRFEGISP
ETWY-SYMDGQPIQTFWVSEWSSGDQGQ---RLSCKPI------PSLV-EKPLLTPDYEL
-LHDL-CLSPEGQVDGSQSNL--QKKFTQLFCGLPSM----HSESLGSTFLCTQGVSKNT
--LKPPY-------KEPHFLK---VSPP-------IPLPEAAPPPSSTSPNE-SLDEPQR
AQIG--GV----PFLTLSECKTLEWHLLQRQL--QLQWGLSAVIARPPRVQSH--TQYKH
KPWNKAKPRETLK-------FFGPGKPFSAFTRELFFIPQHARKLLEFHL-QKRLIHLRW
GLPQRIQRSINMLLSSTDPQSLPCG--GSRLPNVSISQPGKPEAYGSGDTF-LPTAGKGT
TPMPHLFAKAQEMLKSHFDTKCEQIREGKVPACVQSAWKGRIPGDLAA-GTLFPNIPQGQ
P-LELQAEN--NPDLHQEAVSW--KPMDLDQE---AQAFSGVFIEHCRRPQALSEETIKK
LET-TLRHKYLAFLSGLQAL--YCMAPTKATSPT-V---DQSV-ITTM-PW-SVKS--PQ
K-PLSQKSPLEALCLSG----------------------LEPCTQDDKETSANI--AEEF
QHGAQGHGRTE-KVPPERQP-----LLNRPYSLDTEIMERVSFYLKRKALDI--KLGISL
K--E-SVFQEPTATD-LESESVQEPLRSPR--ESTL-LQGPPTLC-HVPVAPDPDKVCL-
--KQPATAVQV----VFQEQNQPSSRAVPHR-SAR----QGSQ---------VHRNMME-
-AQVHYVQMGTGGEMLNLGEPFSTESQS-----PGKSK-SGYVPTVAGKRKIPGKPKVVG
DLGEGDAGLGFSLVSLKTRQDGEQ--EKRLLHRQLQGSSLQAQ-----TF-HLEGACPHS
PQESPELQFADPPP-EVFMETDSE-QDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLP
FPRSPTQRKPSQGQPGPGHVPP--GHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMK
SKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPED-FRG-PKAQ---FS-SSE
KSVVGPCLTPSYILDSKFWPRPR--RVGSVSVLGH-SYHCPRHCPRLAYANQQRNPP---
-----------------------------

-MMVPSFILWDVGSSVYTYG--SLFI-IALIIWHVRRS-HRGLRLGPIKSCT--------
-------------KCF--RRIKQKPSDR--TLRVKKRTTKEETEKLQKLLSNMKRQGWLP
QEGSVRRLLCSDPSCPICNAMALEIQQLLGVENKKTSSSLL------RHS------RSFS
CLEALSPPKVLNDQ-SSELSKVLNGQSSELSKVLNGQSSELSKVLNDQSSELSKVLNDQS
SELSSQHSKDISLPPK--FMQSQSTDQKL-TLSAP--------LSTGN----TVLQC--Y
HPAPQQQPE-PQGSNAFQDVSGLSSSSMDEHGVPANQQKKR-KK--TK--KLVSKNQ-A-
-------------PSEA--EMENKMTF-------FSH-WVNPEVKCDRPEESFAFYKSET
GAKPKTGEPKKSSAKVRAEEPNLE---KHAKDLKAKPLHAKRN----I------------
------------------------------------------------------------
------------------------------------------------------------
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-----------------------------

-MLSPTFVLWDVGYPLYTYG--SIFV-IILIIWQVKRSRH-ELSSEPKRSCC--------
-------------RCH--QKVRQRARDA--ASTVRRH-SQEEAEKPQELLSIIKSQGWLP
PEGSVRRILCADPCCQICNSAALEIQQLLAGENNQISLTLS------GPL------QGSS
CLEMLSLSSMSSDE-CLE------------------------------------------
--FRSWHTRELSLA-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLRGPNTMASLRLEEPRAPLNQ-EM-MQS--NP--SLVQGNQG-Q
HHLNSQDSLLSP-NPET-LNPTHPMALHM--VLPAHLPFLSPEVLRL--LEIHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPVSFNLN--NISQVSLHEFETISL
QTWC-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPALKA
-LSSP-HSLSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKNE
KVPKPPL-------KDPFLFN---KLSF--PQLLPKTPPQSAPRSSPLSPNWVSPSDHQK
AQ-I--NV----PFLTLAECEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCGKAQSPETMT-------TSQPGKSISVLTRELLFFPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIHLLLTSTNQQTVSYSSPA--LANVSIPQSVALEANGACDVL-SPTVAPVS
ILMPHLLTQAKAILQNHIDSKCGQIHQGKIPACVHRSRDCRIPGVLA--VAPLPCIPENQ
L-LELQAAS--DPDLHHKVMPW--MPTALDQQ---QQVLPGTVTQHPKLLRVLSMEAIEK
LET-ILRHKYLVFLSGLTAL--YYVALSRALAPAVT---SQSV-ITEMVPA-PVEI--PA
E-PLTQTVSFEEQCIS-----------------------LGPCPQGNNETCTDV--AKEF
QSVVPVKGTME-MLPLESQT-----QPASPHSLQTHILTKLNFHLRKKVLEI--QWGIPI
K--A-RESREQTATA-PENISTKKSLESLNHQGEAL-LQELPIPP-DTLPAPNPERVHL-
-KEQLANDLKA----VQQNQKQSSSKAVPHG-SAH----WVSKI------SQPSGDMTE-
-AHTLCVRVEASVNKPSMEKLWGPEPQS-----PGKSKDPTHVPMLAGKREEPEETKAAR
DHREGDAGFGHSATREERCPAEEQRPARMLPNQTPRGFWRWSH-----SF-HLADPCQHS
SQHHPQLKLPQLPP-RVPGEKESD-NDLQDNQTELNVILEPETIPENAQTVVPQASQGQL
LLSHPTQCKPLQGQTLQGQVLH--GQVMPAHTQKKPS-LPESSLRNKIKSFLQRSNPKTK
SKGHEDS-MFSA-AKVAKTRKENVAKSLAPAKSPVGRSKTEK-PTGYSKAQ----SLPAQ
KLVGPAFLDGPQSLDNKLWLHSR--QAGSASAPGH-LRHCPRHCPQEACATKPGYPP---
-----------------------------

-MLSPTFILWDMGYPLYTYG--SIFI-IALIIWHVKRS-HRELRLGPDKSCY--------
-------------KCY--RKVKQRPKDR--TSRA-KRTSKEEAEKLQKLLSIMKSQGWLP
QEGSVRKLLCSDPSCPICNAMALEIQQLLGGENKKTSSTPL------RPS------QSFA
CLESLSTSKTF-DK-NPE------------------------------------------
--LCSQYSRDISLVSS--LTPSQSTDQKSSTQSAA--------PSTGD----ANIRY--Y
CPDHQQKQG-PQGSNVSRDAGSLSSSSVEEPGVPANQQKKR-KK--NK--KHVLKKE-E-
-------------PPEA--EAENKMTF-------FSH-WVNPEVKCARPEEPIVLSKSE-
-AKPKTKVPEKSQTPVRDHKERANT-EQTMKDLKAKPLSAKKT----N------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-----------------------------

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----MIQQSIQLLLTSTDQQTLSCSSTA--LANVSIPQPAALEANGACDVP-SPIVAPVS
IPTPHLLTQVKAILQNHIDSKCGQIHQGKIPACVRRSWDCRISGGLA--VAPFPCIPESR
L-LELQTAS--DPDLHHKVMPW--MPMALDQ---QQQALPCTATEHPKLLRVLSREAIEK
LET-TLRHKYLAFLSGLPAL--HYVALSRALTPPVT---SQSV-ITEMVPG-PVEI--PA
E-PPTQMISFEDHCIS-----------------------LGPCPQDNNKTCIDV--AEEF
QPAVPVKGTME-TLPLESWT-----HPASPHSLQTHILTKLNFHLRKKFLEI--QLGIPI
R-----------------NIFTQESLESLNHQGETL-LQELPIPP-DT-SAPNPERVHL-
-KEQLTSEWKA----VQQNQKQSNSKPVPQS-SAH----WVSKI------SQPSGDMTE-
-AHVLCAQVEANVKNPSVEEPWGPQPQS-----PSKSNDPAHIPMLAGKREDLEETKAAR
DHGEGDTGLGLSSTREGRCPAENQRPAGMLPNKTPRGSWRWSH-----SF-HVADPCQHS
PQHHPQLKLPQLPT-GVPRGKESE-NDLQDRQTKINAIFELVRIPENAQTVVPQASQGQP
FLSLPTQSKPLQGQTLQGQVLH--GQVMSSHTPKRPS-LPESSLRNKIKSCLQCINPKTK
GKGHEDS-MFSAAAKVAKTRKENVAKSPAPAKNPVGRSKTEK-PPRHSKVQ----SCPAE
KLAGLAFLDGPQSLENKLQLCSR--QPSSASALGH-PRHCPWHCPRVACVTQPGHLP---
-----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MPDPTLFRRSREN----PSSCTLS--SSSKVIEDRTGIVSH
KTSS-LYSAGQPVQTFWVSKRPVINLQQ---GRPWHQI------HTC-----LPSHEGEH
-LRNF-YPLPRAKANDSGDNL-QSEYYSHLFCGLPSL----HSESLDVTYLSSQGTCKKK
DMSKPST--------DTQPSG---VLSG---LFLPKTPCKSAYPSSPTSLNGKTPCEREG
AQ-I--TV----PFLSLAECEALERHLLKKQL-SKLQWGLPTLLLQNQ---RR--MLCE-
-APSEA---KTVK-------TSLARKPFLHPTRD-I-FPEHTVRLLEFHL-QKQLIHLRW
GLPQRIQRSMNMLLSSTDPQSLPCGS-S-SLPNVSISQPGKPEANGPGDMF-SLTAGKGT
IPMPHLFAKTREMLKSHVDSKCEQIQEGKVPAQVWKSWECKIPGSLAT-VAPFPWIPQGQ
C-RKLQAESKSDPDLLHKVVPW--KPKTLSQE---TQTLSGTLFEHCKKPQSLPKETIKK
LET-TLHHKYLAFLSGLPAL--YCVALSRPASPAVT---SQPR-LREKMPK-AVKS--PS
N-ALTQIT----P--------------------------LEPCTQDDSGVSADT--AEEF
QPGAEADRRTE-KVPAESQP-----PPCRPYPINTHILAKLNFHLKKKDPSN--AVWDF-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTCVLWDVGYPVYAYG--SIFI-IALILWQVKR--RRGLRLGPK-RCF--------
-------------QCH--RRIKPKSKDR--MSRA-KKISQEETKKLQELLSVMKSQGLLP
QKRGVRRLLCADPSCQICNGMALEVQQLLGDKSSKTSLPLL------RPS------QSSS
CLEEIF------------------------------------------------------
----SRQPRDLSLVFG--PTPTQLSGQQSLIQSAV--------PSIGD----VHVKY--Y
LSDHFKQEEEFHMPGELPDMEHLSSSSHEEHRS---SRQKR-KN--ST--KFVCKNQ-E-
-------------DSEV--DMGSKTMF-------FSH-WINPEVKCERYEEPIFLSNAET
LAKPRMKVKSTT--AIKDQVRGGN----LEKLLKAQPPPASKS----I------------
------------------------------------------------------------
------------------------------------------------------------
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-----------------------------

-MLSPTFILWDMGYPLYTYG--SLFI-IALFIWHIKRS-HQGLRLGPNKSCY--------
-------------KCY--RRVKQRPRDR--TPKV-KRTSKEEAEKLQKLLSVMKSQGWLP
QEGSVRRLLCSEPSCSICNAMAKEIQQLLGIENNMASPGSL------RAS------QSFL
SLEALPPSKAELDK-SPE------------------------------------------
--LCPQHSRDVSQASS--LTPSQSTDQKSSTQSAA--------PSTGD----SNVQY--Y
CPAPPPKQE-PQGPNVSRDAGSLSSSSVEEPGVPANQQKRR-KK--TK--KFVLKDQ-A-
-------------PPEA--DSENKMTF-------FSH-WVNPEVKCDRLEEPFVLSKSET
EAEPKIKEPETSHTPVRANTEK------TTKDPKAKALSAKKN----I------------
------------------------------------------------------------
------------------------------------------------------------
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-----------------------------

-MLSPTFVPWDVGYPLYIYG--SIFI-IILIIWQVKRS-HHKLSPEPKRSCC--------
-------------RCH--HKVRQRARGA--ASTARRC-SRKEAEKPQKLLSIIKSQGWLP
PEGSVRRILCADPCCQICNSVALEIQQLLAGENNQISLTLS------GPL------QGSS
CLETLSMSSMSLDQ-SVE------------------------------------------
--FHSWHTGELSPA-SVTPTPSQLTDQKSLTQSAA--------QSTYT----HGIRD--H
WADHLRLGPEFQLPDVLTGPNTMASSRLEKLRAPLNQEEM-MQS--NP--SSVQGNQG-Q
HHLNSQVSLLSL-NPET-LNLMHPMASHM--VLPAHLPFHCPEVMRL--LDVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYHQPGND---QPVSFKLN--NTSQVSLHRFETVSL
QTWC-SCVAGQPTQTFWVSEWSIMNPEQ---RHHCQQS------PNPM-ALALRSPALKA
-LSGP-HPLSGGQDNESGSDL--QQKYSQQFCGLPSL----HSESLVATFMRSQGRPKKE
KVPKPSL-------KDPFLFN---ELSF--PQLLPETSLQSAPPSSPLSPNWVSPSEHQR
AQ-I--NV----PFLTLAEYEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--LQHE-
-PCGKAQPPETMT-------ASQPGKSISVLTREPLFFPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIQLLLTSTDQQIVSCSSTA--LANVSIPQTVALEANGACDVL-SPIAP-VS
IPMRHLLTQAKAILQNHIDSKCEQIHQGKIPACVHRSWDCRISGGLA--VAPLTCIPESQ
F-LVLQRAS--DPDLHHKVMPW--MPTALDQQ---QKALPGAITEHPKLLRVLSMEAIEK
LET-TLRHKHLAFLSGLPAL--YCVALPRALAPAVT---IQSV-ITEMVPR-PVEI--PA
E-PLIQIVSFEEQCIS-----------------------LGPCLQGNNESCTDI--AKEF
QPAVPVKGTME-MLPLESQT-----HPASPHKLQTYILTKLNFHLRKKVLEI--QWGIPI
R--A-RKSREQTAAT-PENKSTQKSLESLNHQGETL-LQELPIPP-DTLPAPNPEGVHL-
-KEQLANDLKA----VQQNQKQSTSKAVPQG-SAH----SVSKI------SQRSGDMTK-
-AHMLCVRVDANVNNPSLEEPWGPEPQS-----PGKSKDPAHVPRLAGKREDPEETKAAR
DHREGDAGFGRSSTREERCPAEDQRPAGMLPNKTPRGSWRWSL-----SF-HLADPCQHS
PQHHPQLKLPQLPP-RVPGEKESD-SDLQDSQAELTVILGPATIPKNAQTVVPQASQGQP
FLSQPTQGKPLQGQTLQGQVLH--GLVMPAHTQKKPS-LPESSLTNKIKCFLQHIIPRTK
GRGHEDS-MFSAAAKMAKTRKENAAKVLAPAKSPVGRSKTEK-PTGCSKAQ----SRPAQ
KLVGPAFLDGPQSLDNKLRLHSR--QPGSASALGY-PHHCPRHCPREACATKPGHPT---
-----------------------------

-MLSSTCFLWDIGYPLYVYF--YIFI-VILIIWQVQQN-YRGLKWEHKRSCC--------
-------------RRH--RKVRQRARDA--ASRARRL-SQEEAEKPWELLSIMKSQSWLP
TEGNVRQLLCVDPCCQICDAATLEIQQLLESDKGQISPALL------ELP------QESS
CLDLLPISSVPFDH-NME------------------------------------------
--FYSGHSTDFSLV----PVTQTLTEQS------T--------QSASA----VDIQQ--F
CDDHFQVGQEFHQEDMAMVSETVASSRFRESVVLVDVGETM-HN--NL--NCVQEIQG-H
QCL NSQICFQTL-SPES-THVTHPMAV--SVVSIVPQPFLSPAVVRL--LELHVKKLMHS
QRWGLPRRVEES---LSQLMPNPPMYFQPENS-HNQHFSFILN--NTSQDCGNRFGSISH
QIWH-AYADSQPIQTFWVSEWSNVDPEQ---ETHREQI------PNPG-GKTLFTPDHNV
-VRSI-CLQPEEQANDSRDNL--QKKFTQLFCGLPSM----HSESLVTTFLGTQDLSQDR
--PRRPC-------EDSHLLT---ESSTSPLPLPPHTPPKAAPPPSSISPNE-CLYEHQE
AQ-I--AV----PFLTLAECKTLEWHLLQRQL--QLQWGLPAVIPGSPYMPRH--IQYK-
-PCNKAKSRETLK-------APWRGKCFSVLTRDLFFVPEHVRRLLEFHF-QKQLIHLRW
GLPQRIQRSIHLLISSADQQALSCSSS----ASVSIPQPGNPEADGSGDRF-ASAVDKGP
IPMPHLFAQAKEMLKSHVDSKCDQIHQGKVPACVQRSWGF--SRSLAA-GTPFPSIPPCQ
P-LESQAES--KPDLHHKVVPQEP---RGDQE---KQALSGTLIEHCKRPQALSEETIKK
LET-TLRHKYLAFLSGLPAV--YCVTPSRTTSPAIV---GQFA-VTEMMPR--P------
VKIPQEPLTLEDPHLSGLEPCPGNGRETPSPCPGDDSKISSPCPGNDNKTS---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---SPCPQDD--------------------------------------------------
-------------------------------------------------S-KKSSPCP--
----------------------------QDYSEVTNAIRQPARVAVVPQPLASQASQGLP
FPRPQIQGKPFRGQTRQDHISR--GRVVPTPPHASPN-LPEASLKNKVKSFLYSINPKIK
GKTHVEP-MVSTPATVAKTSKENVDKGLPQAKSPTKKTKAES-CRG-PRAQ---SAAPTK
KSVMTPFLTAPHILDSKLQPNSR--QHGSVSVSGQ-PRHCPRHCPRLAYATQYRNPP---
-----------------------------

-MLSQTFVLWDLGYPLYTYG--SIFV-IILIIWQVKKS-YHGLT-EHKRSCC--------
-------------RRH--RKVRQRARDA--ALRARRH-SQKEADKLWELLSLMRSQGWLP
QEGAVRQILCADPCCQTCNTMALEIQQL-LGENTLISPTSG------DTS------QGSS
CLEVLSMSNVPFEQ-SLE------------------------------------------
--HRSPHSKDLSVL-SATLT----VSQKSLAQSVA--------QSPSA----AGIHD--Y
WAEHLKLRQGFQVPEVPS--------GTEEPRISVNLQEM-MQS--NL--SLMCGNQV-Q
QPLSPQVSLLPL-KQEI-TTLTHSVALPMVTVLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLVCQTVYN---QPVSFIHN--NTSHFSVEKCGTILY
QNWG-SGMAGQPTQAFWVSEWCVTDPEQ---RHLYQQI------PSHK-ALALPSSALKE
-LSGL-YLMSGQKASDSVGPV--QPKYSQLFCGLPSL----HSESLVDTFLASQGLSNDE
SMSKPHL-------KDPFLLKDPKELSF--LPLLPKTPTQSTPLSSLSCQDCVAPSDHQQ
AH-I--NV----PFLTLDECEALEWHLLQRQL--QLQWDLPDVFQRDQHVQSP--VQCK-
-PGDKAQSSETLK-------TSWSGQPVSVLTREP-VFPQHTRRLLEYHL-QRQLIHHRW
GLPQKIQQSIQLLRSPTNQQTIPWSSTA--LDSVNGPQPTSLGAAGADDPF-SPIVDPLS
VPMPQLFDKAKAILQGHIASRCGQIHQGNIPASVYRSWECIIPEGLE--VTPFSCILESK
P-LELQAAA--DQDLQQEVIPG--MPVALDQQ---QQVSPKAVVEHPKLPGVLSEAAIEK
LEM-TLRHKYLAFLSGLPAL--YCVSPSRVMAPATTSITPPAM-VTEMVPE-PVEF--ST
E-PVTQVTSPEEQGPS-----------------------PGPGFQEANEALSNT--AEEF
QADEQVEGVIE-MLPIESET-----EPERPSSLGEHILAKMNFHLRKKILEA--QIGIPI
K--A-RESREQVVGT-SEDVCTQESLESLNNQGQPL-LQELPIPP-DVPCAPDPEWLHL-
-KEQLATELKA----VHQKQKQPSCSIVPHG-SVH----GASSI------S-VSGDMTE-
-AQVLCVQLEASVNNPSLGEPWSPEPRSPEPHMPDKSKDSAQVPTLAEKREEPGKPILVG
DHGEGDAGFTLSCTRGKSHSVEGQRPEGILLNRTPRSPWQRRH-----RF-HLDASCQHS
AKHCPQPKLPELPPGGVPRGKDSQKKDLQDSQARLSVPLKPARVPENAQPVVPQASRGQT
FLGQLTVGKPLEGRALQGQVFQ--RQVVQGRTHTRPS-LPEYGLRNKIKSLLHCVIPQTK
GKGHEAS-ISSASETVASTRKENVEKSLAPAKSPRGRTKTEK-TRGDLKAQ----FPPAK
KQMGLAFMDVTHSPDSKLRHHSRSHQLLLASVLGT-PATALGTVLEGLVPPNQRTHPNSQ
LSP--------------------------

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-------------------------------------------------------MQHE-
-PCGKAQSPETTT-------ASQTGKSISVLTRELLFFPEHARKLLEFHI-QKQLIHRRW
GLPQKIQQSIQLLLTSTDQQTV SCSSTA--LANVSISQPVALEANGACDVL-SPIVAPVS
IPRPHLLT QVKAILQSHIDSKCGQIHQSKIPACVHRSWDCRISGVLA--VAPVPCIPESQ
F-LVPQTAS--DPDLHHKVMPW--MPTALDQ---QQQALPGTVTEHPKLLRVLSVEAIEK
LET-TLRHKHLAFLSGLPAL--Y-----------YV---AQSV-ITEMVPS-PVEI--PA
E-PLIQMVSFEEQCIS-----------------------LGPCPQGNNESCTDV--AKEF
QPAVPVKGTME-TLPLESQT-----HPTT-----------------KKVLEI--QWGIPI
R--A-RKSREQTAAA-PENISTQKSLESLNHQGETL-LQELPILP-DTLPAPNPEGVHL-
-KEQLANDLKA----VQQNQKQSNSKAVPQG-SAH----SVSKI------SQPSGDMTE-
-AHMLCVQVEASVNNPSLEEPCGPEPQS-----PSKSKDP-----------DPEETKAAR
DHREGDAGFGRSSTREERRPAEDQRPAGMLPNKTPRGSWRWSR-----SF-HLADPCQHS
PQHHPQLKLPQLPP-RVPGEKESE-KDLQDSQTKLTVILEPATIPENAQTVVPQASQGQP
FLSQPTQAKPLQGQTLQRQVLH--GLVMPAHTQKKPS-LTESSFRNKIKCFLERINPKTK
GKGHKDS-MFSATVKVAKTRKENVAKSLAPAKSPVGRSKTEK-PTGCSKAQ----SRPAQ
KLVGPAFLD-----DNKLRLHSR--QPGSASTPGH-PHHCPHHCPRVACAPQPGHPP---
-----------------------------

-MLSPTFVLWDVGYPFYTCG--SICI-IALIMWRLKKS-VQELRLGPNRSSC--------
-------------RCH--RRLKQSSRDR--TSRAGRT-YQEEAEKLQNLLSVMKSQGWLP
QEGSVRRILCADPCCKICNAVALEIQQLLMCENKQISPTSL------TPS------QGSS
CSEILSASSVSFEQ-HQE------------------------------------------
--LGAQSSRELSMT-TLRLTLSKVPDQKSLTSSAA--------QSTNA----VSVQD--N
WADHLQRGQGFQVAGVSQDAGSLSSSSLKKPGVPLNQLERK-NN--SK--SVSKVDK-E-
-------------APEV--GLGNTMKF-------LLH-WINPEVKDQSHEKSTLISDTET
VAKASTKEAEKSPAPTKDPVGRAKL-EKTTEKPKPSLP------------FCNTPSA---
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLTPSLVVENIGYLLYSYG--SIFI-IILLIWQVKRS-YYGLRFKPKRNCC--------
-------------RCH--RKIRQRARDA--ASRAKRC-PRKEAKKLWDLLSTMKSQHWLP
QQESVRQLLCADPSCQTCNAVCLEIQQLLEDEKSQVSPTLS------GPL------QGSS
YLQMMSMSTVSSEK-NRE------------------------------------------
--PHPQRSRDLLRI-SATPALSQQMEQDLTPTI-----------------DDISIQE--Y
FTDHLQRGQEFQWANTPVVQESRDSSELQEPMVPVSGQEM-MQN--KP--NLVQGNQR-Q
HHVKCRVSLPSLHPEFP-DNLTRPMTLHVDSVFPAHLPFFRPKVLRL--LEGHVKKRKHF
QMWGLPRRVEDS--FMRQLMPDAILFSKIGKN---LQLSSILN--STSKVACDKIGIIAQ
QTWC-SYITREPIQSIWVSEWSSTKPQQ---RHYYQQV------QNYD-TLALPSPPAEV
-FTGL-CLPLGGQADDPGSHL--HQKHRQLFCGLPSL----HSESLTASFLSSEGLATNT
NTSRPPS-------KEPLLLQ---GLSF--HPLLPETPPDVCLPSSPLSPNRVSPAGHPE
AH-V--SA----PFLTPAEYKTLEWHLLQRQL--QLRWGLPAIIQRCCHAHSP--KQSE-
-PCDEAQAPETVQ-------TSWPGKPVSVFTRKLPFFPEHTHRLLEFHF-QKQLIRLRW
GLPEKIQQSFQLLLSSADQQTLPCSSTT--FPRVQIPHPTALKGTGDGDPF-SPMLAQMS
LPMPHLLTQAKAKLQGHIDSKCGQIHQGMVPCHVSSSWEGTAPGGVA--VAPFPCVPQGQ
P-RGLQAAS--DSDLHDRVTPW--GPRALGQQ---KQASPDTAAGRPKLHRALTSAAMER
LEM-TVRHKYLVFLSGLPTL--YSSALSEVTAPAIA---SHSP-AAGMAPG-PVEA--PK
E-PLAQVTTPQDPSRR-----------------------LGPCFQNDSETRADS--TD-S
QPEVQREGTME-SAPPESQT-----HPAILHAFKTRLVSRLHFHLRKKVLEI--KLGLPI
R--A-RESREQTTAG-PENKSSRARLTSQNKQGSTV-LQKLPAPP-DSLPAPHSERVHL-
-EEHPASQLQT----LRHSPKPPGSEAAPLA-PSH----QPSEI------SQVSGDVTE-
-AQVLCVQVEAAVNSPGLGEHWDPEPQR-------AGKGSAHIPTPAGKREEAGKPQAAG
DLGEGDAGLGHSLTSAERHPEEEQKPEEMLLKRRPQGSWRWTH-----SC-LLVDPQQHT
PQYHPQLKLAEPPT-ELPGRKESE-HDMQDHGRNVSALLTPAKVPENFHPAVGQASQGQP
FPGQPTPHKPFKGQTLQSRVLQ--GQVTPARSHKRPS-PPESGLVSKMKFFVHYISAVTK
DKNHADS-MLSTPGKAANTSKENVERRLVPAKSPTEKTRTDT-PGRSPKNP----SLPTE
RPVGLASSDVSHSPHSKLRLRSQ--LRGSASVPGH-PHHCPRHCPGVAVPSNQGNRP---
-----------------------------

-MVSPTFVPWDVGHPLYTYG--SICI-IALIIWRLKKS-LQELRLGPNRSCC--------
-------------QCH--RRLKQSPRTC--RTREGQC-H----SIINGFLIFLPSQGWLP
QEGSVRRILCADSGCQTCNAVALEIQQLLVCENNQISPTLL------GPS------QGSS
CSEILSVSSVSFEQ-RQE------------------------------------------
--LGSQSSRELSMA-TLTLTLSKVTDQKSLNPLAV--------QSTNA----VTIQD--Y
RADPLQRGQGFQVAGMSPDAGTLSSSSLEKPGVPLNQQERK-KN--NS--KFVSKGK-E-
-------------DPKV--GLGNTIKF-------LLH-WINPEVKDQNHEKSTVISETEA
VAKASTRGAEKSPTPTKDLVGRANL-EKTTENPRPSLP------------FSA-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSSMYFLWDTEYPLYVYV--CIFI-IILIIWQVQQN-YHGLKFEHKRSCC--------
-------------QRH--QKVRQRARDA--ASRARRL-CREEAEKPRELLSIMKSQSWLP
KKESVRQLLCIDPCCQICNTAALEIQQLLESEKSQISSALL------GLS------QGSS
CLEMLSTSSASFEQ-NME------------------------------------------
--LYSRHPTDFSVV-PVTATLPQPTGHL------T--------QSTNA----VNVQE--H
WDDHLQLGPEL--SDIPVVSETMVSSRPEEPAVLVNE-EII-HS--NL--NFVQEDRN-Q
QSLNSQVPFQTL-NPES-SHFTHPMTL--SIVSTSHQPFLSPEVLRF--LELHVKKWLHF
QRWGLPRRVEES---IRQFMPNPPMYCQPEDN---QPISLTLN--NTSQDHVHRFGH---
-----SYMDSQLTQTFWVSEWPLIHPDQ---RIHCKQI------PSLM-GPSLI--NHKV
-LNGL-SSLFERQTSDSENNF--QKKFTQLFCGLPSL----HSESLDATSQGSQGLSKNK
NMSKATS-------KDPHLLK---ELSR--LPLLPHTPHKAAPPSSSTSPNGESLYEHQG
TQ-I--SV----PFLTPAERKALEWHILQRQP--QLQWGLPDVISGSHHVQSH--MYSE-
-TCQKAQSPKPVK-------ASWPGRSFSVPTKNLVFFPEHTRRLLECHL-QKQLMHLRW
GLPQKIQRSIQLFLSSTDQQPLPCNNRA--LPNMSISQPEGLKANG----F-SPIVGKGS
IAKPHLFSQAKSILKSHIDSKCGQIRQVKVPDCVQRSWECRIPGS------PVPYIPPDK
P-LELQKES--NPNLHHKVIPG--IPKALDQE---KQALPGAVIEHCKQPKSLSEETIKK
LET-ILQHKYLAFLSGLSAF--DCVVPSRVMSPEVP---IQSE-ITETMPG-PINS--PQ
E-PLTQTSLN-----R-----------------------LRPHIQDDKKTSEDT--VKEF
PPERKVEGVTE-KTPLKSQV-----LSASPYS-NTYILAKLNFHLKKKVLEI--KFGIPM
K--S-RKFKKATAAD-PENKFKQESPGNLNNQGSTV-LQKLPISQ--VSPAQDAKWVHL-
-KKHLATEGQA----VHHNPKQACSKSAPHG-SSQ----RGSMI------PQFSKDLTE-
-AQVLCVQVETSGESPSLEEPFSTGAQS-----PDNSKCLSHVPTLIEKREVPRKPKAAG
NLGEGDAGLGLSPTNGKRHHIGDQSPERKSLDRPLQGSWKQRP-----SF-HLVDPCLHS
PYHPPQLKFPSLPL-GGPGGKESE-CDTQDSEAKVNVILRPARIPEITQPMVSQASQDHP
LLGPPNQGRFLWGQTFRDQVLQ--APVMP---TSHKSSLPESGLRNKMKSFLHSINPKMK
GKRYMEY-KISTAGNVVKTN-KNVEKGLAQAKSLTEKTKTEP-SRG-PKPQ---QFAPSK
NAVGTAVLPCPTRQDNKLWLQCR--QQGSASAPGY-THHCPLHCPRLA------------
-----------------------------

-MLDPNFILWDVGYPLYKYG--SIFI-IALIIWHVKRS-YQGLRLGPDKSCY--------
-------------KCY--RRIKHGTRDR--TPKA-KRTSKEEAEKLQKLLTIMKSQGWLP
QEGSVRRLLCSDPSCAICNAMALEIQQLLGYENKETCLTTL------SPS------QTFS
SLEALASSKVLFDK-S--------------------------------------------
----SQDSRDISLASS--LMPSPSTDQKSSTQSAA--------PSTGD----ASFRY--Y
RGDHGQKQE-AQG------AGSLSSSSVEEPGAPANQQKK---K--IT--KLVLKNE-E-
-------------PPEA--EGENKMTF-------FSH-WVNPEVNCEQLEEPIVLCKSET
EAKPKTAEPQKNPTPVRDHTGA-NM-KSTTEDQKAKPLCAKNS----I------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVQQKSGNR--TSRARRT-SQEEAKKLGKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQISLTSQ------GPS------QGSS
GLEALSTSNVSFEH-SQD------------------------------------------
--PGSQKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNIEKSPTVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SIFI-IILIIWQVKRSHH-ELSLEPKRSCC--------
-------------RCH--QKVRQRARGA--ASTVRRR-SQEEAEKPQKLLSIIKSQGWLP
PEGSVRRILCADPCCQICNSVALEIQQLLAGENNQISLTLS------GPL------QVSS
CLEMLSMSSMSLDE-CLE------------------------------------------
--FRSWDTRELSLA-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLRGPNTMASLRFEEPRAPLNQ-EM-MQS--NP--SLVQGNQG-Q
HHLNSQDSLLSL-NPET-LNTTHPMALHM--VLPAHLPFLSSEVLRL--LEVHVKKWVHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPVSFNLN--NISQVSLRGFETISL
QTWC-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPAFKA
-LSSP-HLLSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKNG
KVPKPPM-------KDPFLFN---KLSF--PQLLPKTPPQLAPRSSLLSPNWVSPSDHQQ
AQ-I--NV----PFLTLAECEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCGKAQSPETMT-------TSQPGKSISVLTRELLFFPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIHLLLTSTNQQTVSYSSTA--LANVSIPQPVALEANGACDVL-SPTVAPVS
IPMPHLLTQAKAILQNHMDSKCGQIHQGKIPACVHRSRDCRIPGVLA--VAPLPCIPESQ
V-LELQAAS--DPDLHHKVMPW--MPTALDQQ---QQVLPGTVTQHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRALAPAVT---SQSV-ITEMVPA-PVEI--PA
E-PLTQMVAFEEQCIS-----------------------LGPCPQGNNKTCTDV--AKEF
QSVVPVKGTME-TLPLESQT-----QPASPHSLQTHILTKLNFHLRKKALEI--QWGIPI
K--A-RESREQTAAA-PEKISTQKSLENLNHQGETL-LQELPIPP-DTLPAPNPEWVHL-
-KEQLANELKA----VQQNQKQSSSKAVPHG-SAH----WVSKI------SQPSGDMTE-
-THMLCVRVEASVNKPSTEEPWGAEPQS-----PDKSKDPAHVPMLAGKREDPEETKAAR
DHGEGDEGFGHSSTREERCPAEDQRPAGMLPNQTPRGFWRWSR-----SF-HLADPCQHS
SQHHPQLKLPQLPP-RFPGEKESD-NDLQDNQTELNVILESATIPENAQTVVPRASQSQP
FLSQPTQCKPLQGQTLQGQVLH--GQVMPAHAQKKPS-LPESSLRNKIKSFLQRINPKTK
GKGHEDS-MFSA-AKVAKTKKENVAKSLAPAKSAVGRSKTEK-PTGYSKAQ----SCPSE
KLVGPAFLDGPQSLDNKLWLHSR--QAGSASAPGH-PRHCPRHCPREACATKPGYPP---
-----------------------------

-MLSSACSLWDIGYPLCTYS--SIFI-IFLIAWQIRRS-YQGLSLEPKKSCC--------
-------------RRH--RKVRQRARDV--ASRARRL-PQEEAEKPWELLTIMKSQSWLP
KEEHVRQLLCVDPCCQICDAASLEIQQLLQSERSQTSS-GL------GLP------PGSS
CLEMVPISRVSFEQ-NME------------------------------------------
--LRSRHSRRLPLA-SGTPILAQLTEHL------S--------QSTSA----VGVRQ--C
WADHLQLDQKFPLADMPRISETMASSRLKEPVVLMIEEKLM-QN--KA--KFDEESQD-R
HHVKSSVSLLPL-TPKT-TNLTRTMSLQMNSVPPSRVPLLSPKVRRI--LELHVKKWIHF
QKWGLPRRVEES---LRQLVPGRTLFCQSRKN----VLSSILS--SGSEITMDRAGTISC
QTNR-LYLTDQPTQTCWVSEWSFINLKQ---RKPWHQI------RTY-----LSSRELEH
-LSGF-YAPRKAQANDSGSNL-QSDYRGQLFCGLPSL----HSESLDVTSLSSQGVSQNI
PKSSSAD-------RQP--TR---ELSL---PFLPQTPRKSAPLSSPASPNAKTPREHER
AQ-I--NV----PFLTLAECEALECHLLERQV--KLQWGLPAVFLRKRYTWSH--MLCE-
-PHGKT---TTIK-------TYWPRKPFSYPTREFS-FPEHVRRLLEFHL-QKQLIHLRW
GLPQRIQRSIHSLLSSTDQQSRSCSS-R-ALPDVSIPQPGHPEADGSGDKF-ALAVDKGS
ISTPRLFSQTKAMLENHIDSKCGQIHQGKVPAQVWRSWERKIPGTPAA-VTPSSWIPQGQ
H-PELQAESQSNPDLHPKAAPL--EPEAFEQE---QQASSGTLIEHCKRPHALSKEMIKK
LET-TLQHKYLAFLSGLPAL--YCVALSRPISPTVT---SQPR-TTEMMSR-PVKS--SP
E-ARTQLT-------------------------------SLPCPRDDKEASADA--TGEV
QPDGQAEGRTE-KVSLDSRT-----RD-SARSINSHILAKLNFHLKKKVLAM--QFGISE
K--E-RENKELALAS-PENESLQEFLRSLGIPEGTE-LQKLPRSG-DSPPAPDANRVPL-
-KKQPATAGQP----VCHKPSQPSSRTVPHG-SAQ----WGSKA------SKL-RNKME-
-AQ--------------P----------------------------------G-KPKAVG
DFGERDADFGLSPTSEKTHHDGDQEPEKGPLHRTPQGSSQQRQ-----SV-HLEDPSLPS
PQEPSDLEFPEPPP-KVFIEREPE-HDMQDSQAKVNVIPKP--------SVASQASQGLP
FPRSPTQGKPFGGQTWQDHISR--GRVMPTSPHASP-SLPEAGLKTKMKSFFHSINPKIK
GKTHVEPI-DSTPGKAVKTSKENVDKGLPQAKSPTKKTKTEN-CRG-PKAQ---SA-SSE
KSVIASFLTAPHISDSKLRPGPR--QFGSVSAPGR-PRHCPRHCPLLAYAIQYRN-----
-----------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------QICDAATLEIQQLLESDKGQISPALL------GLP------QESS
CLDLLPVSSVPFEG-NME------------------------------------------
--LHSRHSRHLSLT-PGTPTLAQLTEHL------T--------QSTSA----VGVQQ--C
WADHLQLEQKLHLADIPMISETVVSSGLEDPVVLMIEEKIM-QN--KP--KLGQESQD-Q
HPLKSSVSLLSL-NPEI-TNLTHAVSLHMDSMLSPHVPLLSPKVRRL--LELHVKKWIHF
QKWGLPRRVEES---LRQLMPDLTLFCQSRKN----LLSSVLS--NGSEVPMNKAGIISH
-------------QTCWVSEWSVKNLKQ---RPHWHQI------HSC-----LHSHE-DL
-T-SS-SPSPKAQSNDSGSSL-QNEYYSQLFCGLPSL----HSESLDVTSLSAQGVSKNK
SVPKSSS-------RDPRYTK---ELSL---SFLPKTPRKSAPPSSPASPDAKTPHEHEG
AQ-L--AV----PFLTLAECEALERHLLERRV--KLQWGLPGVLLRNQYSQSH--VLCE-
-PHGKA---EAVK-------AFWPRKFFSDPTRKLS-FPEHVRRLLEFHF-QKQLIHLRW
GLPQRIQRSIHLLISSADQQALSCSSSA----SVSIPQPGNPEADGSGDRF-ASAVDKGP
IPMPHLFAQAKEMLKSHVDSKCDQIHQGKVPAQVWSSRECKIPGILAA-TVPFPWISQGQ
H-LKLQAQSKGKPGLHHQVAPW--KAAAL-DQ---EKVLSGALIEHCKRPQALSEETIKK
LET-TLQHKYLAFLSGLPAL--YCVALSRPTSPVVT---IQPR-TTELMSV-PVKS--PP
R-TVTQTI---SL----------------------------EGPLGDDKAPANT--TGEL
QPEVQVEGRTD-CR-----T-----HD-SPHLLNTHILAKLNFHLKRKVLAI--QFGISE
K--E-REYKELAIAD-LESESIQEFLRSLSIPESTA-LQKLPKSG-DLPAAPDASTVHL-
-GKRPAAAGQA----VCHKPSIMSKIYLNNVNQMA----FR---------ADL-GGRFE-
-TEFLCVVLWFWNS---LCRP-------------------------------S-WPQT--
------------------HRDSPACVS---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SIFI-IILIIWQVKRSHH-ELSSEPKRSCC--------
-------------RCH--QKVRQRARGA--ASTVRRR-SQEEAEKPQKLLSIIKSQGWLP
PEGSVRRILCADPCCQICNSVALEIQQLLAGENNQISLTLS------GPL------QGSS
CLEMLSMSSMSLDE-CLE------------------------------------------
--FRSWHTRELSLA-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLRGPNTMASLRFEEPRAPLNQ-EM-MQS--NP--SLVQGNQG-Q
HHLNSQDSLLSP-NPET-LNPTHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPVSFNLN--NISQVSLRGFETISL
QTWC-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPAFKA
-LSSP-HSLSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKNG
KVPKPPM-------KDPFLFN---KLSF--PQLLPKTSPQSAPHSSPLSPNWVSPSDHQQ
AQ-I--NV----PFLTLAECEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCAKAQSPETMT-------TSQPGKSISVLTRELLFFPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIHLLLTSTNQQTVSYSSTA--LANVSIPQPVALEANGACDVL-SPTVAPVS
IPMPHLLTQAKVILQNHMDSKCGQIHQGKIPACVHRSRDCRIPGVLA--VAPLPCIPESQ
V-LELQAAS--DPDLHHKVMPW--MPTALDQQ---QQFLPGTVTQHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRALAPAVT---SQSV-ITEMVPA-PVEI--PA
E-PLTQMVSFEEQCIS-----------------------LGPCPQGNNETCTDV--AKEF
QSVVPVKGTTE-TLPLESQT-----QPASPHSLQTHILTKLNFHLRKKALEI--QWGIPI
K--A-RESREQTAAA-PENISTQKSLENLNHQGEAL-LQELPIPP-DTLPAPNPEWVHL-
-KEQLANDLKA----VQQNQKQSSSKAVPHG-SAH----WVSKI------SQPSGDMTE-
-THMLCVRVEASVNKPSTEEPWGPEPQS-----PDKSKDPAHVPMLAGKREDPEETKAAR
DHREGDEGFGHSSTREERCPAEDQRPAGMLPNQTPRGFWRWSR-----SF-HLADPCQHS
SQHHPQLKLPQLPP-RFPGEKESD-NDLQDNQTELNVILESATIPENAQTVVPRASQSQP
FLSQPTQCKPLQGQTLQGQVLH--GQVMPAHAQKKPS-LPESSLRNKIKSFLQRINPKTK
GKGHEDS-MFSA-AKVAKTRKENVAKSLAPAKSPVGRSKTEK-PTGYSKAQ----SCPSE
KLVGPAFLDGPQSLDNKLWLHSR--QAGSASAPGH-PRHCPRHCPREACATKPGYPP---
-----------------------------

-MLSPVFLLWDVEYSLYTYG--SIFI-IGVIIWQVRKR-CQKLTLRPTKNCC--------
-------------QHH--QRVKQRSGEA--TLRAKGS-SQKEAERLQKLVSLMESQEWLP
QEGSVRRLLCADPSCRICNATALEIQQLLVGRNNQISPTFS------KPF------QSSS
PLGMLSPASVPFGR-SRK------------------------------------------
--LVFQDSRELLWT-SG-PTLWQLTDQKYLTQSAS--------QSTGG----ASVPE--H
RSDHLQTA---RVPRVFRAARAHSSPSLKEAGIHGNWKERT-KN--KP--KLALMSS-G-
-------------APEV--DLENTMTF-------FSH-WINPEVKDHRHKESVLHRKCET
GAKSSTKEVEELPTLTKA-----HL-EKTVNGHEAQPPCTEKG----QNFF---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLMPTLVLWDAGYHLYTYG--SIFI-IVLIIWHMKRS-RGGLRLEPIKNCC--------
-------------KCH--RRVKQRPRDR--TSRV-MRTSKEEAEKFQKLLSTMKSQGWLP
QEGSVRQLLCADPSCKICNAVALEIQQLLGFENKKPSPILL------RPS------QSSS
CLDTLSTSKVMFEK-SQE------------------------------------------
--LSSQHSRNLSVVFG--QTSSQLTGQKLSTQSAA--------PSTDD----ANVQC--Y
NSDHKRKQG-FQGSKVSQDAGSQSSSSLEEPGAPSKQQKRR-KN--NT--SSV-SKQ-K-
-------------APEV--EVENKMTF-------FSH-WINPELKCERHEEPILLSNSET
VAKPRTKEVEKNQASK-DQEDEANT-EKTTKHPKDQALPIKNM-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

MMLIPPFILWDVGYSVYTYG--SIFI-IALIIWQVKRS-HRGLRMGPTKSCAKDVFILVG
GHRCPVIAEVLWSLCF--RRIKQTPSDR--ATRA-KRTSKEEAEKLQKLLDTMKSQGWLP
QEGSVRRLLCPDPSCSICNAMTLEIQQLLGVENKKTSSSLL------RPS------RSFS
CLEALSPSKSLADR-SSE------------------------------------------
--LTYQDTRDVSLSSR--FPQSQETDQQS-TRSAT--------PSIGD----AVLQC--Y
HSAPQQQLD-PQGSKMTQDAKGLSSSSTDEPGVPANQQKKR-KK--TK--KLALKNQAA-
-------------PTEV--ETENKMTF-------FSH-WVNPEVKCDRQEESLVFSKYDT
GAKPMTVEPEKTHSPVRDQAEGAEKKKKPECDLKAKPLRAKRN----I------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVQQKSGNR--TSRARRT-SQEEAKKLGKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQISLTSQ------GPS------QGSS
GLEALSTSNVSFEH-SQD------------------------------------------
--PGSQKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNVEKSPTVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFILWDVGYPFYTYG--SIII-IALIIWQVKKN-QQDVKLGPKRNCC--------
-------------RRH--QKVKQRAKEK--TPREVCL-RPH-----TDKEADVTAHGWLP
QEGSVRRLLCADPCCQICNSVALEIQQLISCETTLTTATSS------GPS------QGSS
CLEVLSISN-SLSF-DQE------------------------------------------
----SLPFKQLSLP-SATRTVSQVTNQKSVTQSAAKSATKPATKSASA----ISIRQ--Y
WAGHQQLRQECRGSELPLDAGAVSFVSLEKPRIPVNQHVKK-KS--KS--EGILKKQ-E-
-------------AVEA--DLGNKLKH-------FTH-GINPDTKGQGHKECILRCKDEK
AAKTKRKKAEKSPPSTKRPMNGAKL-EKEE-------------------GFFDALQCLDS
EFQRQS---VQSGQSCF-LPLSSGS------SKGSPLLTRATQPENPSHVSICTSA----
--KGT-CLPQES-----------TQSRKKELRGSQTS-------------------ASS-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSSAFVLWDIVYLLYTYG--SIFI-IFLIIWQVSWN-YHGLRFECKRSCC--------
-------------QRH--QKIRQRARNA--ASRARRR-YQEESEKPRELISVMKSQHWLP
EQESVRQLLCADPSCQTCNAVALEIQQLLEDEKNQISPALS------GPS------QG S-
CLEMVSMSAVSFKQ-NLE------------------------------------------
--VHSQHPRDLSLA-SVPPTLTQL-AERVMQST-----------------NTISVRE--Y
RADRVHQGQECHLALVPMGPETAATLGFEQPVAAVSEQEM-MQS--NP--NYVQGNQD-Q
QSVN SPQISFMYVNPGI-ANLTRPVAFHMV--PLVHFPFLSPEVLRL--LEGHVRKWMHF
QRWGLPRRVEDS---LRQLMPNTALYCQTEN N---EPVSLILN--NNSRVCVCEFGTTAR
QTWC-SYMAGQSTQSFWVSEWSDVNPEQ---RHQQR--------SNTM-GLSLPFPSPKV
-LGGL-YPLPGGQADD PGSHL--HQKHRQLFCGLPSL----HSESLTASFLSSEGLATNT
NTSRPPS-------KEPLLLQ---GLSF--HPLLPETPPDVRLPSSPLSPNRVSPAGHPE
AH-V--SA----PFLTPAEYKTLEWHLLQRQL--QLRWGLPAIIQRCRHAHSP--KQSE-
-PCDEAQAPETVQ-------TSWPGKPVSVFTRKLPFFPEHTHRLLEFHF-QKQLIRLRW
GLPEKIQQSFQLLLSSADQQTLPCSSTT--FPRVQIPHPTALKGTGDGDPF-SPMLAQMS
LPMPHLLTQAKAKLQGHIDSKCGQIHQGMVPCHVSSSWEGTAAGGVA--VAPFPCVPQGQ
P-RGLQAAS--DPDPHDRVTPW--GPRALGRQ---KQASPDTAAGRPKLHRALTSAAMER
LEM-TVRHKYLVFLSGLPTL--YSSALSEVTAPAIA---SHSP-AAGMAPG-PVEA--PK
E-PLAQVTTPQDPSRR-----------------------LGPCFQNDSETWADS--AD-S
QPEVQREGTTE-SAPPESQT-----QPAILHAFKTRLVSRLHFHLRKKVLEI--KLGLPI
R--A-RESREQTTAG-PENKSSRARLTSQNKQGSTV-LQKLPAPP-DSSPAPHSERVHL-
-EEHPASQLQT----LRHSPKPPGSEAAPLA-PSH----QPSEI------SQVSGDVTE-
-AQVLCVQVEAAVNSPGLEEHWDPEPQR-------SGKASAHIPTPAGKREEAGKPQAAG
DLGEGDAGLGHSLTSAERHPEEEQKPEEMLLKRRPQGSWRWTH-----SC-LLVDPQQHT
PQYHPQLKLAEPPT-ELPGRKESE-HDMQDHRRNVSALLRPAKVPENFHPAVGQASQGQP
FPGQPTPHKPFKGQTLQSRVLQ--GQVTPAHSHKRPS-LPESGLVSKMKFFVHYISAMTK
GKDHADS-MLSMPGKAANTSKENVERRLVPAKSPTEKTGTDT-PGRSPKNP----SLPTR
RPVGLASLDVSHSPHSKLRLRSQ--LRGSASIPGH-PRHCP----QVACPSQSGNPP---
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SIFI-IILIIWQVKRSHH-ELSSEPKRSCC--------
-------------RCH--QKVRQRARGA--ASTVRRR-SQEEAEKPQKLLSIIKSQGWLP
PEGSVRRMLCADPCCQICNSVALEIQQLLAGENNQISLTLS------GPM------QVSS
CLEMLSMSSMSLDE-CLE------------------------------------------
--FCSWDTRELSLA-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPEVLRGPNTMASLRFEEPRAPLNQ-EM-MQS--NP--SLVQGNQG-Q
HHLNSQDSLLSP-NPET-LNPTHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWVHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPVSFNLN--NISQVSLRGFETISL
QTWC-ACVAGQPIQTFWVSEWSTMNPEQ---RPHCQQS------PNPM-ALALPSPAFKA
-LSSP-HLLSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKNG
KVPKPPM-------KDPFLFN---KLSF--PQLLPKTSPQSAPRSSLLSPNWVSPSDHQQ
AQ-I--NV----PFLTLAECEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCGKAQSPETMT-------TSQPGKSISVLTRELLFCPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIHLLLTSTNQQTVSYSSTA--LANVSIPQPVALEANGACDVL-SPTVAAVS
IPMPHLLTQAKAILQNHMDSKCGQIHQGKIPACVHRSRDCRIPGVLA--VAPLPCIPESQ
V-LELQAAS--DPDLHHKVMPW--MPTALDQQ---QQVLPGTVTQHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRALAPAVT---SQSV-ITEMVPA-PVEI--PA
E-PLTQMVSFEEQCIS-----------------------LGPCPQGNNETCTDV--AKEF
QSVVPVKGTME-TLPLESQT-----QPASPHSLQTHILTKLNFHLRKKVLEI--QWGIPI
K--A-RESREQTAAA-PENISTQKSLENLNHQGEAL-LQELPIPP-DTLPAPNPEWVHL-
-KEQLANDLKA----VQQNQKQSSSKAVPHG-SAH----WVSKI------SQPSGDMTE-
-THMLCVRVEASVNKPSTEEPWGPEPQS-----PDKSKDPAHVPMLAGKREDPEETKAAR
DHREGDEGFGHSSTREERCPAEDQRPAGMLPNQTPRGFWRWSR-----SF-HLADPCQHS
SQHHPQLKLPQLPP-RFPGEKESD-NDLQDNQTELNVILESATIPENAQTVVPRASQSQP
FLSQPTQCKPLQGQTLQGQVLH--GQVMPAHAQKKPS-LPESSLRNKIKSFLQRINPKTK
GKGHEDS-MFSA-AKVAKTKKENVAKSLAPAKSAVGRSKTEK-PTGYSKAQ----SCPSE
KLVGPAFLDGPQSLDNKLWLHSR--QAGSASAPGH-PRHCPRHCPREACATKPGYPP---
-----------------------------

-MLSSTYFLWDTEYSLYAYF--YIFI-IILIIWQVQQN-YHRLKCEHTRSCC--------
-------------RRH--RKVRQRARDA--ASRARRL-SREEAEKPWELLTIMKSQSWLP
KEEHVRQLLCVDPCCQICDAASLEIQQLLQSERSQTSPG-L------GLP------PGSS
CLEMLPISRVSFEQ-NME------------------------------------------
--LHPRHSRRIPLA-SGTPILAQLTEHL------S--------QSTSA----IGVGQ--C
WADLLQAGEEFHRTDMPMGSETVASSGFREPVVLMTAGGTM-HN--NL--NYIQQNQD-H
QSFNSQISFQTL-NPES-TRTMHPMTL--SLVTTVPQPFLSPEVLRL--LELHVKKLVHF
QRWGLPRRVEES---LRQLIPNPPMYFQPENN---QPVSFILN--TSSRNYVDRFGNISH
QTWC-SCTDSQPTQTFWVSEWSNVDPGP---KTHCEEI------PSPV-GKPLFTPDHNV
-LRGI-CLLPEGQANDSRNNL--QKKCTQLFCGLPSR----HSESLVTTFLGTPDLSKDT
--PRSSY-------TDPDLLK---ESPH--FPLLPHTLPKAGPPSSSTSSKE-SLYEHQD
PQ-L--SV----PFLTLAECKTLEWHLLQRQL--QIRWGLPAVIPRSPYVQSH--IQYK-
-PCNKTKPHETLK-------ASCPGKSFSVLTRDLFFIPDHTRRLLEFHL-QKHLIHLRW
GLPQRIQRSIHSLLSSTDQQSRSCS-SR-ALPDVSIPQPGHPEADGSGDKF-ALAVDRLP
IPMPHFFVQAKAMLKNHVDSKCDQIHQGKVPACVQSSWERRTPAILAG-GTPFSKMSPGQ
P-LELQAEN--DSDLHPKAVP--LEPETFEQE---QQASSGTLIEHCKRPHALSKETIKK
LET-TLRHKYLAFLSGLPAL--YCVTPSRATSPEIV---SQSA-PTEMPPG-PVKI--PQ
EQSLTQMIPLEVPCRSR----------------------LEPCTRDEQAASVNT--TGEV
QSEGQVKRRTE-KVSLDSQ---------------REILGKLNFHLKKKVLEI--KLGIPV
T--A-DDLKELNAAG-PESESMQEPIRSLGILEGTE-LQKLPSSG-DSPPAPDANRVPL-
-KKQPATAGQP----VCHKPSQPSSRTVPHG-SAQ----WGSKA------S-KLRNKME-
-AQVYCIQMETSGEEPSLEKPFSTEPQS-----PGKSKSSAHVSTMTEKIEEPGKPKAVG
DFEERDADLGFSPTSEKTHHDGDQEPEKGPLHRTPQGSSQQRQ-----SV-HLEDPCLPS
PQEPSDLEFPEPPP-KVFMEREPE-HDMQDSQAKVNVTPKAAKIAKVPQSVASQASQGLP
FPRSPTQGKPFGGQTWQDHISR--GRVMPTSPHASPS-LPEAGLKTKMKSFFHSINPKIK
GKTHVEP-KVSTPGKVAKTSKENVDKGLPQAKSPTKKR-------G-PKAQ---SA-SSE
KSVIASFLTAPHISDSKLWPGPR--QFSSVSAPRR-PRHCPRHCPLLAYAIQYRNPP---
-----------------------------

-MLSYIYFLWDIEYPLYVYF--YIFI-IILIIWQVKQN-YQGLKWEQKRSCC--------
-------------RRH--QKVRQRARDA--ATQARRL-TQEESEKPWELLSIMKSQSWLP
TEGNVRQLLCVDPCCHICESATLEIQQLLESDKSQISPA LP------ELP------QVSS
CLDMLPISSVPFDD-NTK------------------------------------------
--FYSRHSTDFALV----PVTQMPMEHS------T--------QSVNA----VGIQQ--V
CDDHFQVGQEFDQSDMAMVSEAVASSSLRGSVVLVNAGQSM-HS--NL--IYVQQNQGYH
QSLN SQIPFQTL-NPES-THVTHPVSL--SVVNILPQPFLSPSVVRL--LELHVKKLMHS
QRWGLPRRVEES---LSQLMPNPPMYFQPENN---RPVSFILN--NTSQDCGNRFGSISH
QTWY-SYTDSQPMQTFWVSEWSNVEPEQ---KTHCKQI------PSPG-RKPLFTPDHNV
-AHGI-CLQPEGQAKEPRDNF--QKKFTQLFCGLPSM----HSESLVTTFLGTRGLSKDS
--SRPSC-------EDPHLLK---ESST--LPLLPYTPPMAAPPPSSVFPNE-CLYEHKE
AQ-I--TV----PFLTLAECKTLEWHLLQRQL--QLQWGLPAVIPGSPYMPSY--IQYR-
-PCNKAKPRETLK-------ATWPGKCFSVLTRDLFFVPEHVRRLLEFHL-QKQLIHIRW
GLPQRIQRSIHLLLSSANEHALSCSRSR-ALSSVSIPKPGSPEADGSGDRF-ASAVDKGP
ILMPHLFVQAKAKLKIHVDSKCDQIHHDKVPACVQRSWEF--CRCLSA-GTPFPSVPPGQ
S-LKPQAEN--KPDLHHKVVPQEP---TSDQE---ERPVSCAFIEHCKRPQSLSEETIKK
LET-TLRHKYLAFLSGLPAL--YCVAPSRATSPA-V---GQFA-VTEIVVK-KP------
QKSLTQVTSLEDPRLS--SPCPRDVIKASSPCPHDDIEMLHPCSRDDSEVSADI--TEEV
QPEVQVEGKTE-MVPLESQT-------PSPSSLNTELVARLSFHLKKKVLEI--KLGIPI
T--A-RELQEPNAVG-SGTEHPQELVGSLSIPESIE-LQKLPDSG-DLPPAPDASTDHR-
-KKQPATAVQA----VCHQRKKPSSKAVSQG-SVH----WNSKA------S-QLRNVTK-
-AQVPCVQTETSGEKPNLEEALSTEPHG-----PGKSKYSDHVPKLTGKSQEPGKPKAVG
DFGEGDTGLGFSPTSEGTHHDEDQEPEEGPVHGTPEGSSQHSH-----SF-HPEDPCPPS
PQNTPELEFPDPPP-EVFMEREPE-LDTQDSQTKANAIQEHARIAEVPQPVASWASQGIP
FPRPLIQGKPFRVQTRQDRISRGQGRVMPTSPQASPS-LPEAGLKNKVKSFLQSINPKIK
GKTHVEP-MVSTPATVAKTSKENVGKGLPQAKSPTQKTKAEN-CRG-PKAQ---SA-PAE
KSVIASFLTAPHILDSKLRPNPG--QHGSVSISGQSPRHCPRHCPKLAYATQHRNPP---
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLSLGPNRSCC--------
-------------RCH--RRVQQKSGDR--TSRARRT-SQEEAEKLWKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIKQLLAGENNQISLTSL------GPS------QGSS
CLEALSTSSVSFEH-SQD------------------------------------------
--LGSPKSKELSLA-SVTPTLLQLMDQKSLTQSAA--------RSAGT----GSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLTQQERK-KN--NS--KLVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPETKDRRHEESILLSKAET
VTQDRTKNIEKSPTVTKDHVWGATT-EKTTEDPEAQPPSTEEE----GLIFCDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSSMCFLWDTECSLYVYF--YIFI-VVLIVWQ--------------------------
--------------RH--QKVRQRARDA--ASRARRL-SREEAEKPWELLSIMKSQSWVP
KEGNVRQLLCVDPSCHICEAMTLEIRQLLQSEKSQFSPALL------GQP------HGPA
CLEM-PISSESFEW-NQE------------------------------------------
--FCSSYSTNSPVA-PGNQTLTQLPEQL------T--------QSTNA----DGVQL--C
WTDPLQVGQEFHLADMPMTSETVASPGLEESVVLMNEEDTV-YS--NL--NYIQQLQD-H
ETLNSQIPFQTL-TPQI-T-VTYPMAV--SIVTDAPQPFLSPEVLRL--LEIHVKKLMHF
QRWGLPRRVEES---LKQLMPNPPMYFQPERN---QPDSFILN--TSSQDCVHRFEGICP
QTWY-SPMDGQPIQTFWVSEWSSGDPGQ---RLSCKPI------PSPV-EKPLLTPDYEL
-FRDL-CLPPEGQADGSQSNF--QKKFTQLFCGLPSM----HSESLGSTFLCTQGVSKNT
--LNPPY-------KEPHFLK---VSPP-------FPLPEAAPPPSSTSPNE-SLYEPQR
AQMG--GV----PFLTLSECETLEWHLLQRQLQLQLQWGQPAVISGSPRTQSH--TRYKH
KPRNKAKPRETLQ-------VFGPGKPFSVLTRELFFIPQHARRLLEFHL-QKQLIHLRW
GLPQRIQRSMQMLLLSTDPQSLPCSGGGSRQPNESTSQPRKPEADGSGDTF-LP---KGT
IPMPHLFAKAKAMLKSHVDTKCEQILEGKVPACVQSSWKGRIPGNMAA-GTLFPNIPQGQ
P-LELQAEN--NPDLHQEAVSW--KPMDPDQE---AQVFSGAFTEHCRRPQALSEETIKK
LET-TLRHKYLAFLSGLQAL--YCVAPTRATSPI-V---DQSV-ITTL-SW-PVKS--PQ
K-PLSQKSPLEALCLSG----------------------LEPCTQDDEETSANI--AEEF
QRGARGDGRTE-RVPPERQP-----LLIRPYSLNTEIMERLSFHLKKKVLEI--KLGISL
K--G-SAFQEPTAAD-SESESVQEPLGSPQ--ESTL-LQEPPTLC-HSPVAPDSDKVHL-
--KQPATAVQA----VFQEQNQPSSRAVPHR-SAQ----QGSQ---------VHRDMME-
-AQMHYVQMGTGGEMLNLMEPFSTESQS-----PGKSK-SGHVPTVIGKSKDPGKPKAVG
DLGEGDAGLGFPLVSQKTRQDGEQ--EKQLLHRPRQGSSQQGH-----AF-HLQGACPHS
PRESPELQFPHPPP-AVFMETDSE-QDTEGSQSEESIVPEPARTAEAPQPVLSQASQGLP
FPCSPTQRKPLQGQPGPGHFPP--GHTMPASPSTRPSRLPEAGLKNKMKFFFHSINPKMK
SKAHTEPSMGSTPGKVAKISKENVERGLPRAKSPTKKTKPED-SRG-PKAQ---FL-SSE
KSVVGPCLTPSYILDSKFWPRSR--QVGSVSVLGH-PYHCPRHCPRLAYATQQRNPP---
-----------------------------

-MLSPTFVLWEVGYPLYIYG--SIFI-VIVIIWQVKRS-HHELSSEPKRSCC--------
-------------RCH--QKVRQRARDA--ASTARRR-SREEAEKPQKLLSIIKSQGWLP
LEGSVRRILCADPCCQICNSVALEIQQLLVGENNQISLTLS------GPL------QGSS
CLEMLSTSSMSLDQ-SLE------------------------------------------
--FRSWHTRELSLS-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADQLQLGQEFQVPDVLRGPNTIASSRLEKPRAPLNQEEM-MQS--NP--SLVQGNQG-Q
HHLNSQVSLLSL-NPET-LNRMHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPVSFNLK--NTPQVSLHRFETISL
QTWY-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPALQA
-LSGP-HPQSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFTGSQGLPKIE
NVPKPPL-------KDPFLFN---ELSF--PQLLPKTSPQSAPPSSPLSPNWVSPSDHQR
AQ-I--NV----PFLTLAEYEGLGVHLLQRQL--QLQWGWPAALQRLSTP----------
-----------------------SASFISVLTRELLFFREHARKLLEFHI-QKQSIHHRW
ACLRRSASPSSCSLPPLTQQTCVLQQHS--PGQGSISQPVALEPTGLRCAV-THLRPE-C
PSPGTLVNSGQAILQNHINSKCGQSPPGQDPRLCNRSWTGRISGSWN--C----------
-----RQQV--DPDLHHKVMPW--MPTALDQQ---QQALPGTVTEHPKLLRVLSVEAIEK
LET-TLRHKHLAFLSGLPAL--YYVALPRALAPAVT---SQSV-ITEMVPS-PVEI--PA
E-SLIQMVSFEEQCIS-----------------------LGPCPQGNSESCTDI--AKEF
QPAVPVKGTME-TLPLESQT-----HPTSPHSLQTHILTKLNFHLRKKVLEI--QWGIPI
R--A-RKSREQTVAA-PENISTQKSLESLNHQGETL-LQELPILP-DTLPAPNPEGVHL-
-KEQLANDLKA----VQQNQKQSNSKAVPQG-SAH----SVSKI------SQPSGDMTE-
-AHMLCVQVEANVNKPSLEELWGPEPQS-----PGKSKDPAHVPMLAGNREDPEETKAAR
DHREGDAGFGCSSTREERRPAEDQRPAGMLPNKTPRGSWRWSR-----SF-HLADPCQHS
PQHHPQLKLPQLPP-RVPGEKESE-KDLQDSQTKLTVILEPATIPENAQTVLPQASQGQP
FLSQPTQAKPLQGQTLQGQVLH--GLVMPAHAQKKPS-LPESSFRNKIKCFLQHINPKTK
GKGHEDS-MFSAAAKVAKTRKENVAKSLAPAKSPVGRSKTEK-PTGCSRAQ----SRPAQ
KLVGPAFLDGPQSLDDKLRLHSR--QPGSASALSY-PRHCPRHCPREACATKPGHPT---
-----------------------------

-MLNSECFLWDIEYPFYAYS--FIFI-TILLAWQVTRT-YQQLKLEPKRSCC--------
-------------RHH--RKVRQRARDA--ASTARRL-CQEEAEKPRELLSIMKSQSWQ-
---SVRQLLCVNSCCQICDAATLEIQQLLESEKSQISSALL------GLS------QGSS
CLEMLSTSSASFEQ-NME------------------------------------------
--LYSRHPTDFSVV-PVTATLPQPTGHL------T--------QSTNA----VNVQK--D
WDDHLQLGP--ELSDMPVVSEIMASSRPEEPAFLVVDEEII-QN--KP--KLDQENQD-H
HQLKSSVSLLCL-NPEI-TNLTHTMSLHMNSILPAHLPLLSPKAHRL--LEVHVKKWIHF
QKWGLPRRVEES---LKQLMPDPTLFCRSGKN----QLSSILN--KTTKVTIDKIKTVSH
QTKS-SCLAGQPTQTCWVSEWSLENMEQ---INHWHQI------QTY-----NALA----
--SQE-FEPPLAQANDSASNF--QKKYNQLFCGLPSL----HSESLDATFLNSNGLSKNM
S--KPTS-------KDPLLLK---KPSL---FFLSKTPLKSALPPSPTSPNGKSSYEYEG
AQ-V--SV----PFLTLDECEALECHLLQKQV--KLQWGPPAVFLRSWYTQSH--LQCE-
-PHDKAQTPKTVK-------TSWPRIPFSPLTRELC-FPEHTCRLLEFHL-QKQLIHLRW
GLPQKIQRSIQLFLSSTDQKPPPCSN-R-ALPNVSISQPEGLKAVGSGTMF-SPTVSKGL
IPMPQMFAQSKAILQSHIDSKCKQVHQGKVPAHICSSWECRIPGGSAE-GSPFPCISQGE
P-LKLQAES--NLNLHDKGTPW--IPKALDQE---KKAVPHAFIEHCKRPQSLSKDIIKK
LET-ILQHKYLAFLSGLPSL--YCVALSRPTSLAVT---NRSR-IPEMLLP-K-------
--------PSKVL--------------------------LKSCTDDDNKDSVDT--AEKL
QPELQVKGMME-RT----RP-----HS-TNPYSNTHILAKLNFHMKKKVLAM--QFGISE
K--E-NQFKEETVIG-PKNQSKQKSLKSLNNQESTV-LQKPKEDA-DLGLSQTNGKGHHT
GQQKQATELQA----VYHNQKQPD--------SAQ----WASKI------SQFSRDLTE-
-AQMLCVDVEASDENSNLEEL-------------------------------HRKSKVAE
NIGEEDAGLVLSQTNGEGHHTGEQSPEKKFPNNKPQGSQKQKP-----SF-HSVAPCPWS
PQHPPQPKFQNPHP-NILGRKDSE-HDLPVSESKVNVILKP--------SRTPGIVQPT-
-VYQASQGHPF----------LGPPSMIPASPHKKP-NFPESSWRSKMKSFLYSISPKMK
GKTHTETM-FSTVGKVTKTTKENFEKNLTQAKSSTKETETEI-SRG-PKPQ---SV-PPD
KPVGT---------PEKLRLRSR--QQGSASGPGN-ARHCPRHCPQLAHAAQHGN-----
-----------------------------

-MLSHTFVLWDFKYPLYTYG--FIFI-ILLIIWRVTKS-YHGLRLEPQRICC--------
-------------QRH--RKVR--IRDA--ASRARRF-CQEEADKPWELLSVMRSQDWLP
QEGSVRRLLCADTCCQICNAMALEIQQLLVGENTLISSPSS------GPL------QGSS
CLEILSMSTVSFEQ-SLQ------------------------------------------
--QRSLHCKALSFR-SATPPVLELMDQKCLTQSAV--------QSTDA----VRIHD--C
WAEHLQLGQGFQIPEVTCVPETMSCLRLEEPQVPVNQQQM-IQS--TP--GLVCGNQG-H
WPLNSQVSLQTL-NREI-TTLTHP MAWHMVTVLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLFCQAINN---QPVSFIQK--NTS KFSIETLGPYSC
ENWA-SCMANQPTQAFWVSEWSIMGPEQ---RHHQQQI------PNHM-ALALPSPALKD
-SSAL-YALPGYQNHDSV GHL--QQKYIQLFCGLPSL----HSESLVNTFLGSQNFSMNG
SVSKHPL-------KDPFL-K---DFSI--LPLLPKTPPQSDASSSPSSQNWVIPSDNQQ
PQ-N--SV----PLLTLAECNALEWHLLQRQL--QLRWGLSAVFQRPQNTQNP--MQYR-
-PYGRAQSPE--K-------TSWPVKPITVLTRELVFFPEHGRRLLEFHL-QRQLIHHRW
GLPQKIQESIQLLLSSSDQSTLSWSSTA--LATVHAPQPTALEAPGAGDPF-SPVTDQVP
VPMPHLFDQAKAILQSHINSKCGQIHQGKVPACVCSSWQCIIPGGLQ--VAPFTCIPESK
P-LELQATT--DPALQQKAGAW--IPTALDQQ---QQAPPDPVTEHIKLPQALSEGAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRAMAPAIS---TQAV-ITGMVPG-PGEF--PT
E-PLTQMISSEEQCLS-----------------------PGPCFQDANKTCADT--AEER
QVEEQVEQMIE-EVPLESQA-----EASELYTLKKPILAKLNFHLRKKILEI--QLGIPI
K--A-RESREQTGAT-PDNTSTQESLRSLNNQGKTL-LQDLPIPP-DAPRAPDPEWLHL-
-KEQLAIELKA----VQQNQKQPSSRAVPHG-SAH----WASKI------SPPSGDMKE-
-AQVLCVHLEASANSPSLEEPWSPEPQS-----PGKSKDSAQVPMLAEKREDPGKPKLAG
DHGEGDAGFACSFTREISDPDEAQRPKGILLNRAPRTPQRKSH-----NF-HLAAPFEHN
TRHHPQIKLPEPSP-GIPGVKVSEKNDLHDSLTKLSVILKPARIPKNVQPMVPQASQGQP
FLGQLIQARPLQGQTLKGQVLQ--GQEMPVHTHKRPS-LPEAGLRSRMKSFLYCFNSKMK
GKGHKES-MFSIAGKVANPRKENVQKILAPAKSPVGQTNTQK-TRGNSKAQ----SSPTE
KQVCLGFLDGPHSPDSKLRHRSHSHQLHSASVLDH-PRHCPRHCPRMACVTQSGNAP---
-----------------------------

-MLIPACSFWDIGYLLCTYT--SIFA-IFLTAWQVRRS-YQRLSLEPKESCY--------
-------------RHH--RKVRQRARDA--ASRARRL-SREEAEKPWELLSIMKSQSWVP
KQGNVRQLLCLDPSCQICEAATEEIQQLVQSEKSQLSPAFL------GLN------QGSA
HSAHLEMLPMSFEQ-NME------------------------------------------
--LCSRHTRPHPRV-PGNQTLTQLTGHL------T--------QLTNT----FGVQE--C
WTDRLQLDQNFHLANMPVVSETVTSSRLKEPMVLMIEETIV-QS--KA--KLDQESQD-L
HHVKSSVSLLSL-DP----NLTHTMSLHM DSMLSSHLPLLSPKVRGL--LELHVKKWIHF
QKWGLPRRVEES---LRQLMPDPTLFRRSREN----PSSCTLS--SSSKVTED RTGIVSH
KTSS-LYSAGQPVQTFWVSKWPVINLQQ---GRPWHQI------HTC-----LPSHEGEH
-LRNF-YPLPRAKAN DSGDNL-QSEYYSQLFCGLPSL----HSESLDVTSLSSQGICKKK
DMSKPST--------DAQPSG---VLSG---LFLPKTPCKSAFPSSPTSLNGKTPCEREG
AQ-I--TV----PFLSLAECEALERHLLKKQL-SKLQWGLPALLLQNQ---RR--MPCE-
-ALSEA---KTVK-------TSLARKPFLHPTRD-I-FPEHAGRLLEFHL-QKQLIHLRW
GLPQRIQRCMNMLLSSTDPQSLPCGS-S-SLTNVSISQPGKPEADGPGDMF-LLTAGKGT
IPMPHLFAKTREMLKSHVDSKCEQIQEGKVPAQVWKSWECKIPGSLAT-VAPFPWIPQGQ
C-RKLQAESKSDPDLLHKVVPW--KPKTLSQE---TQTLSGTLFEHCKKPQSLPKETIKK
LET-TLHHKYLAFLSGLPAL--YCVALSRPASPAVT---SQPR-LREKMPK-AVKS--PS
R-ALTQIT----P--------------------------LESCTQDDSGVSADT--AEEF
QPGAEADGRTE-KVPAESQP-----PPCRPYPINTHILAKLNFHLKKKILAM--QFGISE
K--EKREHKELGTAD-LESESIQEFLRSLHTSESTL-LQEQPVAC-PSLPAPNAKGVHP-
-KKQPASAVQD----VCQAQRPPPSKAVPHS-SAQ----QSSKA------SHSQRD----
-KIQVCVDTEAGGKRFNLE-----------------------------------KSKVVG
DLGEGDAGLGFSLVGQKTRQDEEQ--EKRLLHRPLQGSSQQGH-----TF-HLEDACPHS
PWESPELQFPDPPP-EVFMETDSE-QDMD-SQSEESIVPEP--------PVLSRASQGLP
FPRSPTQRRPSQGQPGPGHFPP--GHEMPASPYMRPSHLPEAGLKNKMKFFFHSINPKIK
SKAHTEPSTVSTPGKVAKTSKENVERGLPQAKSPTKKTKPED-SRG-PKAQ---FS-SSE
KSVMASLLTAPHILDSKLRPRSR--QLGSVSVLGN-SRHCPRHCPRLAYASHHRN-----
-----------------------------

-MLSPTFVLWDAGYPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVKQKSRDT--TSKARRT-SQEEAEKLWKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNAMALEIQQLLVNENSLISLTSL------GPS------QGSS
CLEALSTSSASFEQ-SQD------------------------------------------
--LGTEKSKEHSLA-SVTTTLSQLTDQKSLTESAT--------QSAGT----DSIQD--S
WADHFRRGQRSQVPAVSQGMGSLS-SNFEKHGIPLSQLESK-KN--NS--QFVLENQ-E-
-------------APEV--RLDNKMKL-------FLH-WINPEMKDRRHEESIFLSKAKR
VTQDRTENTEKSPTVTKDHVWVATT-EKTTEDPEAQPPSTEEE----GLIFRDAPST---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SIFI-IILIIWQVKRSRHHELSLEPKRSCC--------
-------------RCH--QKVRQRARDA--ASTVRRR-SQEEAEKPQKLLSIIKSQGWLP
PEGSVRRILCADPCCQICNSVALEIQQLLAGENNQISLTLS------GPL------QGSS
CLEMLSMSSMSLDE-CLE------------------------------------------
--FRSWHTRELSLA-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLQGPNTMASLRLEEPRTPLNQKEM-MQS--NP--SLVQGNQG-Q
HHLNSQLSLLSP-NPET-LNPTHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPVSFNLN--NTSQVSLHRFQTISL
QTWY-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPALKA
-LSSP-HLLSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKNE
KVPKPPL-------KDPFLSN---KLSF--PQLLPKTPPQSAPHSSPLSPNWVSPSGHQQ
AQ-I--NV----PFLTLAECEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCGKAQSPETMT-------TSQPGKSISVLTRELLFFLEHARKLLEFHI-QKQLIHRRW
GLPQKIQQSIHLLLTSTNQQTVSYSSPA--LANVSIPQPVALEANGACDVL-SPTVAPVS
ILMPHLLTQAKAILQNHINSKCGQIHQGKIPACVHRSWDCRIPGVLA--VAPLPCIPESQ
V-LELQAAS--DPDLHHKVMPW--MPTALDQQ---QQVLPGTVTQHPKLLRVLSVEDIEK
LET-TLRHKYLAFLLGLPPL--YYVVPSRALVQAVT---SQSV-ITEMVPA-PVEI--PA
E-PLTQMVSFEEQCIS-----------------------LGPCPQGNNETCTDI--AKEF
QSVVPLKGTME-MLPLESQT-----QSASPHSLQTHILTKLNFHLRKKVLEI--QWGIPI
K--A-RESREQTATA-PENISTKKSLESLNHQGEAL-LQELPIPP-DTLPAPNPEGVHL-
-KEQLANDLKA----VQQNQKKSSCKAIPHG-SAH----WVSKI------SQPSGDMTE-
-THMLCVRVEASVNKPSMEKPWGPEPQS-----PGKSKDPTRVPMLAGKREDPEEIKAAR
HHREGDAGFGHSSTREERCPAEDQRPAGRLPNQTPRGFWRWSR-----SF-HLADPCQHS
SQHHPQLKLPQLPP-RVPGEKESD-NDLQDNQTELNVILEPEIIPENAQTVVPQASQGQP
LLSHPTQCKPLQGQTLQGQVLH--GQVMPAHTQKKPS-LPESSLKNKIKSFLQHINPKTK
SKGHEDS-MFSA-AKVAKTRKENVAKSLAPAKSPVGRSKTEK-LTGYSKAQ----SLPAQ
KLVGPAFLDGPQSLDNKPWLHSR--QAGSASAPGH-LRHCPRHCPREACATKPGYPP---
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-CQKLSLVPNRSCC--------
-------------RCH--RRVQQKSGDR--TSRARRT-SQEEAEKLWKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIKQLLAGENNQISLTSL------GPS------QGSS
CLEALSTSSVSFKH-SQD------------------------------------------
--LGSPKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------RSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERT-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNIEKSPTVTKDHVWGATT-QKTTEDPEAQPPSTEEE----GLIFCDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLRSTYFLWDSDYPLYVYI--YIFV-VILIIWQVQQN-YRRLKWEQKRSCC--------
-------------RRH--RKVRQRARDA--ASRGYSK-PQTHPSIINGGRFSLPSQSWLP
KEERVRQLLCIDPCCQICDAATLEIRQLLESEQSQISPALL------GLP------QDSS
CLEMLTISSETFEQ-NVE------------------------------------------
--LHPRPSTDFPPA----PVTQTLTEHL------T--------QSAST----VGVQQ--L
CADHLLAGQGFHLADMSMVSEAAASSRLREPVVLVNAEEMM-HS--DLSYNYLQQIQD-Q
QSFNSQTPFQTL-SPDG-IHVTHPMTL--SLVTTVPPPFLNPEVVRL--LELHVKKLMHF
QRWGLPRRVEES---LRQVMPHPPMYFQPENN---QPVSLILN--NIPQDYVHRFGSLSP
NTWC-SYPDNQPTQIFWVSQWSNAELGQ---KAHHGQI------TSPV-EKPLFSPDHDI
-LRGI-WLLPKGQANDSRNKL--PKTFTQLFCGLPSI----HSESLVATFLGTQRLSKDT
--PEPSC-------KDPQLLK---EASP--FLLPPHLPPTAAPPSS-ASPKE-SWYEC-Q
TQ-I--NV----PCLTLAECKTLEWHLLQRQL--QLQWGQPAVIPGSPYEQSH--IQYK-
-PYNKAKPHETLK-------ASWARKSFSVLTRDLVFIPEPVRRLLELHL-QKQLIHLRW
GLPQRIQRSIHLVPSSPGQQPR-----G-ALPNVSILQPGDPKADGSGDMF-AVAVDRGS
VPTPHLFSQAQAMLKTHVDSKYGQIHQGKVPACVQSSRECRIPRSLSV-GASFSNIPASR
H-LELQAKS--NPDLQHTAVSQEAEPAALDQE---KQASSGTLIEHCKLPQALPEETVKK
LET-TLRHKYLAFLSGLPVH--YCVTPSRSTSPATV---SHST-VTEIIPG-PVKI--PQ
EP-LTQVTLLEDPYRSR----------------------LEPCTQDENETSEDI--AGEV
QPKVQAAGGTE-KVPLETQ---------------TEILAKLSFHLKKKVLEI--KLGFPV
I--A-KEFKESNAVD-PE------PLGILRIPGSTA-LPQLPNTG-YSPPAPDANRVHL-
-GKRPATAGQA----VCHKQKQPSSKTAPHG-SAQ----WGSKA------S-QLRNMTE-
-AQGHCVQLETSGEKPNLEKTFSTEPQS-----PGKSKYSAHAPTLTEKSHASGKPKAVW
DLEEGDAGLGLPLTSGKTHHDRDEELEKRPPPETPQGSSEQRP-----RS-H-----PPS
PQDLSEFEFPDPPP-EVLMVIDTT-QNMQDSLTKVDAIPEPARSAKVPQPVASKTSQGLP
FPCTPTQGKPFRGQAWQENISQ--RQVTPASPHASPS-LPETGLKNKMKSFLHSMSPKIK
DKTHMEP-PVSTPRKVSKPSQENADKDLPQAKNPTKKTKTEN-CRM-PKAQ---PV-SSE
RPVVTSFLTAPHILDSKLGPGSR--QHGSVSGPGQ-PQHCPRHCPRLACATQYRNPP---
-----------------------------

--MYPQSADWGGGLSAV------------------------SCH-SRLLDSC--------
-------------RMSLNPLLFRVTLSP--GFSARRH-SRKEADKLRELLSLMRSQGWLP
QEGAVRQILCADPCCQTCNTMALEIQQL-LGENTLISPTSG------DTS------QGSS
CLEVLSMSNVPFEQ-SLE------------------------------------------
--LRSPHSKDLSVL-SATLT----VSQKSLAQSVA--------QSPSA----AGIHD--Y
WAEHLKLRQGFQVPEVPS--------GTEEPRISVNLQEM-MQS--NL--SLMCGNQV-Q
QPLSPQVSLLPL-KQEI-TTLTHSV ALPMVTVLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLVCQTV YN---QPVSFIHN--NTSHFSVEKCGTILY
QNWG-SGMAGQPTQAFWVSEWCVTDPEQ---RHLYQQI------PSHK-ALALPSSALKE
-LSGL-YLMSGQQASDSV GPV--QPKYSQLFCGLPSL----HSESLVDTFLASQGLSNDE
SMSKPHL-------KDPFLLKDPKELSF--LPLLPKTPTQSTPLSSLSCQDCVAPSDHQQ
AH-I--NV----PFLTLDECEALEWHLLQRQL--QLQWDLPDVFQRDQHVQSP--VQCK-
-PSDKAQSSETLK-------TSWSGQPVSVLTREP-VFLQHTRRLLEYHL-QRQLIHHRW
GLPQKIQQSIQLLRSPTNQQTIPWSSTA--LDSVNGPQPTSLEATGADDPF-SPIVDPLS
VPMPHLFDKAKAILQGHIASRCGQIHQGNIPASVYRSWECIIPGGLE--VTPFSCILESK
P-LELQAAA--DQDLQQEVIPG--MPVALDQQ---QQVSPKAVVEHPKLPGVLSEAAIEK
LEM-TLRHKYLAFLSGLPAL--YCVSPSRVMAPATTSITPPAM-VTEMVPE-PVEF--ST
E-PVTQVTSPEEQGPS-----------------------PGPGFQEANEALSNT--AEEF
QADEQVEGVIE-MLPIESET-----EPERPSSLGEHILAKMNFHLRKKILEA--QIGIPI
K--A-RESREQVVGT-SEDVCTQESLESLNNQGQPL-LQELPIPP-DVPCAPDPEWLHL-
-KEQLATELKA----VHQKQKQPSCSIVPHG-SVH----GASSI------S-VSGDMTE-
-AQVLCVQLEASVNNPSLGEPWSPEPRSPEPHMPDKSKDSAQVPTLAEKREEPGKPILVG
DHGEGDAGFTLSCTRGKSHSVEGQRPEGILLNRTPRSPWQRRH-----RF-HLDASCQHS
AKHCPQPKLPELPPGGVPRGKDSQKKDLQDSQARLSVPLKPARVPENAQPVVPQASRGQT
FLGQLTVGKPLEGRALQGQVFQ--RQVVQGRTHTRPS-LPEYGLRNKIKSLLHCVIPQTK
GKGHEAS-ISSASETVASTRKENVEKSLAPAKSPRGRTKTEK-TRGDLKAQ----FPPAK
KQMGLAFMDVTHSPDSKLRHHSRSHQLLLASVLGT-PRHCPRHCPRGACATQPKNSP---
-----------------------------

-MLSPAFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLSLGPNRSCC--------
-------------RCH--RRVQQKSGDR--TSRARRT-SQEEAEKLWKLLFLMKSQGWLP
QEGSVRRILCVDPCCQICNVMALEIKQLLAGENNQISLTSL------GPS------QGSS
CLEALSTSSVSFKH-SQD------------------------------------------
--LGSPKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------WSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEEFILLSKAET
VTQDRTKNIEKSPTVTKDHVWGATT-EKTTEDPEAQPPSTEEE----GLIFCDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWDVRYPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------QCH--QRVQQKSGDR--TSRARRT-SQEEAKKLWKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQFSLTSQ------GPS------QGSS
CLGALSTSNVSFEH-SQD------------------------------------------
--LGSPKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----ESIQD--S
WADHFQGVHTYK----------------------------------------SIILP-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNVEKSPTVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAP-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-----------------------------

-MLSPTFVLWDVGHPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVQQKSGDR--TSRARRT-SQEEAKKLWKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQISLTSQ------GPS------QGSS
CLGALSTSNVPFEH-SQD------------------------------------------
--LGSPKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--SLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNVEKSPTVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-----------------------------

-MMVPSFILWDVGSSVYTYG--SLFI-IALIIWHVRRS-HRGLRLGPIKSCT--------
-------------KCF--RRIKQKPSDR--TLRVKKRTSKEETEKLQKLLSNMKRQGWLP
QEGSVRRLLCSDPSCPICNAMALEIQQLLGVENKKTSSSLL------RHS------RSFS
CLEALSPPKVLNGQ-SSELSKVL-----------NGQSSELSKVLNDQSSELSKVLNGQS
SELSSQHSKDILLPPK--FTQSQSTDQKL-TLSAP--------LSTGN----TVLQC--Y
HPAPQQQPE-PQGSNAFQDVSGLSSSSMDEHGVPANQQKKR-KK--TK--KLVSKNQAA-
-------------PSEA--EMENKMTF-------FSH-WVNPEVKCDRPEESFAFYKSET
GAKPKTGEPKKSSAKVRAEEPNLE---KHAKDLKAKPLHAKRN----I------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-----------------------------

-MLSYIYFLWDIEYPLYVYF--YIFI-IILIIWQVKQN-YQGLKWEQKRSCC--------
-------------RRH--QKVRQRARDA--ATQARRL-TQEESEKPWELLSIMKSQSWLP
TEGNVRQLLCVDPCCHICDSATLEIQQLLESDKSQISPA LP------ELP------QVSS
CLDMLPISSVPFDD-NTK------------------------------------------
--FYSRHSTDFALV----PVTQMPMEHS------T--------QSVNA----VGIQQ--V
CDDHFQVGQEFDQSDMAMVSEAVASSSLRGSVVLVNAGQSM-HS--NL--IYVQQIQGYH
QSLN SQIPFQTL-NPES-THVTHPVSL--SVVNILPQPFLSPSVVRL--LELHVKKLMHS
QRWGLPRRVEES---LSQLMPN PPMYFQPENN---RPVSFILN--NTSQDCGNRFGSISH
QTWY-SYTDSQPMQTFWVSEWSNVEPEQ---KTHCKQI------PSPG-RKPLFTPDHNV
-AHGI-CLQPEGQ AKEPRDNF--QKKFTQLFCGLPSM----HSESLVTTFLGTRGLSKDS
--SRPSC-------EDPHLLK---ESST--LPLLPYTPPMAAPPPSSVSPNE-CLYEHKE
AQ-I--TV----PFLTLAECKTLEWHLLQRQL--QLQWGLPAVIPGSPYMPSY--IQYR-
-PCNKAKPRETLK-------ATWPGKCFSVLTRDLFFVPEHVRRLLEFHL-QKQLIHIRW
GLPQRIQRSIHLLLSSANKHALSRSRSR-ALSSVSIPKPGSPEADGSGDRF-ASAVDKGP
ILMPHLFVQAKAKLKSHVDSKCDQIHHDKVPACVQRSWEF--CRCLSA-GTPFPSVPPGQ
S-LKPQAEN--KPDLHHKVVPQEP---TSDQE---ERPVSCAFIEHCKRPQSLSEETIKK
LET-TLRHKYLAFLSGLPAL--YCVAPSRATSPA-V---GQFA-VTEIVVK-KP------
QKSLTQVTSLEDPRLS--R--------------------LEPCPRDDIKVSADI--TEEV
QPEVQVEGKTE-MVPLESQT-------PSPSSLNTELVARLSFHLKKKVLEI--KLGIPI
T--A-RELQEPNAVG-SGTEHPQELVGSLSIPESIE-LQKLPDSG-DLPPAPDASTDHR-
-KKQPATAVQA----VCHQRKKPSSKAVSQG-SVH----WNSKA------S-QLRNVTK-
-AQVPCVQTETSGEKPNLEEALSTEPHG-----PGKSKYSDHVPKLTGKSQEPGKPKAVG
DFGEGDTGLGFSPTSEGTHHDEDQEPEKGPVHGTPEGSSQHSH-----SF-HPEDPCPPS
PQNTPELEFPDPPP-EVFMEREPE-LDTQDSQTKANAIQEHARIAEVPQPVASWASRNIP
FPRPPRG------------RGRERGQVMPTSPHASPS-LQEVGLKNKVKSFLQSINPKIK
GKTHVEP-MVSTPAKVAKTSKENVGKGLPQAKSPTQKTKAEN-CRG-PKAQ---SA-PAE
KSVIASFLTAPHILDSKLRPHSG--QHGSVSISGQSPRHCPRHCPKLAYATQHRNPP---
-----------------------------

-----MCFLWDTECSLYVYF--YIFI-VVLIVWQ--------------------------
--------------RH--QKVRQRARDA--ASRARRL-SREEAEKPWELLSIMKSQSWVP
KEGNVRQLLCVDPSCHICEAMTLEIRQLLQSEKSQFSPALL------GQP------HGPA
CLEM-PISSESFEW-NQE------------------------------------------
--FCSSYSTNSPVA-PGNQTLTQLPEQL------T--------QSTNA----DGVQL--C
WTDPLQVGQEFHLADMPMTSETVASPGLEESVVLMNEEDTV-YS--NL--NYIQQLQD-H
ETLNSQIPFQTL-TPQI-T-VTYPMAV--SIVTDAPQPFLSPEVLRL--LEIHVKKLMHF
QRWGLPRRVEES---LKQLMPNPPMYFQPERN---QPDSFILN--TSSQDCVHRFEGICP
QTWY-SPMDGQPIQTFWVSEWSSGDPGQ---RLSCKPI------PSPV-EKPLLTPDYEL
-FRDL-CLPPEGQADGSQSNF--QKKFTQLFCGLPSM----HSESLGSTFLCTQGVSKNT
--LNPPY-------KEPHFLK---VSPP-------FPLPEAAPPPSSTSPNE-SLYEPQR
AQMG--GV----PFLTLSECETLEWHLLQRQLQLQLQWGQPAVISGSPRTQSH--TRYKH
KPRNKAKPRETLQ-------VFGPGKPFSVLTRELFFIPQHARRLLEFHL-QKQLIHLRW
GLPQRIQRSMQMLLLSTDPQSLPCSGGGSRQPNESTSQPRKPEADGSGDTF-LP---KGT
IPMPHLFAKAKAMLKSHVDTKCEQILEGKVPACVQSSWKGRIPGNMAA-GTLFPNIPQGQ
P-LELQAEN--NPDLHQEAVSW--KPMDPDQE---AQVFSGAFTEHCRRPQALSEETIKK
LET-TLRHKYLAFLSGLQAL--YCVAPTRATSPI-V---DQSV-ITTL-SW-PVKS--PQ
K-PLSQKSPLEALCLSG----------------------LEPCTQDDEETSANI--AEEF
QRGARGDGRTE-RVPPERQP-----LLIRPYSLNTEIMERLSFHLKKKVLEI--KLGISL
K--G-SAFQEPTAAD-SESESVQEPLGSPQ--ESTL-LQEPPTLC-HSPVAPDSDKVHL-
--KQPATAVQA----VFQEQNQPSSRAVPHR-SAQ----QGSQ---------VHRDMME-
-AQMHYVQMGTGGEMLNLMEPFSTESQS-----PGKSK-SGHVPTVIGKSKDPGKPKAVG
DLGEGDAGLGFPLVSQKTRQDGEQ--EKQLLHRPRQGSSQQGH-----AF-HLQGACPHS
PRESPELQFPHPPP-AVFMETDSE-QDTEGSQSEESIVPEPARTAEAPQPVLSQASQGLP
FPCSPTQRKPLQGQPGPGHFPP--GHTMPASPSTRPSRLPEAGLKNKMKFFFHSINPKMK
SKAHTEPSMGSTPGKVAKISKENVERGLPRAKSPTKKTKPED-SRG-PKAQ---FL-SSE
KSVVGPCLTPSYILDSKFWPRSR--QVGSVSVLGH-PYHCPRHCPRLAYATQQRNPP---
-----------------------------

-MLSPTFVLWDVGYPLYIYG--SILI-IILLIWQVKRS-HHELRMEAKRSCC--------
-------------RHH--QKVRQRARDG--ASTARRH-SQEEAEKPQKLLSVIKSQGWLP
PEGSVRRILCADPCCQICNSVALEIQQLLADENNQVSLTLS------GPL------QGSS
CLEMLSVSSMSLDQ-SLE------------------------------------------
--FCSRHTRELSLA-SVTPTLSQLTDQKCLTQSAA--------QSSGT----NSIQD--Y
LADHLRLGQEFQVQDVLRGPNVMVSSRLEDSGTPLNQEET-MHS--NP--SHVQGNQG-Q
HHLNSQVSLLSL-NPET-LNPTHPMALHM--VLAAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPLSFNLN--NTSQFSLHRYEIISH
QTWC-SCMAGQPMQTFWVSEWTVMNPEQ---RHHCEQS------PNPV-ALALPSSALNA
-LRCP-HPLSGGQNNDSGSDL--QQKCSQLFCGLPSL----HSESLNTTFMGSQGLSKNE
NVPKPSL-------KDPFLFN---KLSF--PHLLPKRPPQSAPPSSPLFPNWVSPSDHQR
AQ-I--NV----PFLTLAEREALEWHLLQRQL--QLQWGLPPVLQRSQHTQCP--MQHE-
-PCGKAQSPETMT-------TSQPGKTISVLTRELL-FPEHARNLLEFHI-QKQLIHHRW
GLPQKIRQSIQL LLTSTVQQTLSCSSTA--LANVSIPQPAALEANGACDVAPSPIVAPVS
IPTPHLLT QVKAILQNHIDSKCGQIHQGKIPACVHRSWDCRISEGLA--VAPFPCIPESQ
L-LELQTAS--DPDLHHKVTPL--MPMALDQQ---QQDLPCTATEHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVVLSRALTPPVT---SQSV-ITEMVPR-PMEI--PA
G-PPTQMISFEDHCIS-----------------------LGLGPQDNNKTCTEV--AEEF
QPAVPVKGTME-TLPLESQT-----HPASPHSLQTHILTKLNFHLRKKVLEI--QLGIPI
R--A-RESREQSATV-PENVFTQESLESLNHQGETL-FQELPIPP-DT-PAPNPERVHL-
-KEQPANEWKA----VQQNKKQSNSKAVPQS-SAH----WVSKI------SQPSGDMTE-
-AHVLCVQVEANVNNPNLEEPWGPEPQS-----PSKSNVPAHIPMLAGKREDPEETKAAR
NHREGDTGFGLSSTREERPPAEEQRPGGMLPNKTPRGSCRWSH-----SF-HHADPCQHS
LQHHSQLKLPQLST-GVPGGEESE-NDLQDRQTEINAIFELARIPENAQTVVPQASQGQP
FLSLPTQSKPLQGQTLQGQVLH--GQVMPPHTHKRPS-LPESSLRNKIKSFLQCINPKMK
GKGHEDS-MYSAASKVAKTRKENIAKSPAPAKNTVGRSKTEK-PPRHSKAQ----SRPAE
KLVGRAFLDGPQSLENKLRLHSR--QPSSASASGQ-PRHCPWHCPQVACVTQPGHLP---
-----------------------------

-MLSPAFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLSLGPNRSCC--------
-------------RCH--RRVQQKSGDR--TSRARRT-SQEEAEKLWKLLFLMKSQGWLP
QEGSVRRILCVDPCCQICNVMALEIKQLLAGENNQISLTSL------GPS------QGSS
CLEALSTSSVSFKH-SQD------------------------------------------
--LGSPKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------WSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNIEKSPTVTKDHVWGATT-EKTTEDPEAQPPSTEEE----GLIFCDAPSA---
------------------------------------------------------------
------------------------------------------------------------
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-----------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------MALEIQQLLVGENDQISPTLS-----RSPS------QVSS
CLEILSVSSVSFEQ-SLE------------------------------------------
--LRSRNTRELSLA-SVTPTLSQLTDEESLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLTGPNTTASSRLEEPRVPLNQEEM-MQS--NP--SFVQGNQG-Q
HHLNSQVSLLSL-NPET-LNPTHPMALHM--VLPAHPPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQSGND---QPVSFNLN--NISQVSLHRFETISL
QTWC-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPALKA
-LHDP-HLLSGGQDNDSGSDL--PQKYSQLFSGLPSL----HSESLVATFMGSQGLPKNE
NVPKPPL-------KDPFLFN---KLSF--PQLLPKTPPQSAPRSSLLSPNWVSPSDHQQ
AQ-I--NV----PFLTLAEYEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCAKAQSPETMT-------TSQPGKSISVLTRELLFFPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIHLLLTSTNQQTVSYSSTA--LANVSIPQPVALEANGACDVL-SPTVAPVS
IPMPHLLTQAKVILQNHMDSKCGQIHQGKIPACVHRSRDCRIPGVLA--VAPLPCIPENQ
L-LELQAAS--DPDLHHKVMPW--MPTALDQQ---QQLLPGTVTQHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRALAPAVT---SQSV-ITEMVPE-PVEI--PA
E-PLTQMVSFEEQCIS-----------------------LGPCPQGNNESCTDV--AKEF
QSVVPVKGTME-TLPLESQT-----QPASPHSLQTHILTKLNFHLRKKVLEI--QWGIPI
K--A-RESREQTAAA-PENISTQKSLESLNHQGEAL-LQELPIPP-DTLPAPNPEWVHL-
-KEQLANDLKA----VQQNQKQSSSKAVPHG-SAH----WVSRI------SQPSGDMTE-
-AHMLCIRVEASVNKPSMEEPWGPEPQS-----PGKSKDPARVPMLAGKREDPEETKAAR
DHGEGDEGFGHSSTRGERCPAEDQRPARMLPNQTPRGFWRWSR-----SF-HLADPCQHS
SQHHPQLKLPQLPP-RSPGGKESE-NDLQDSQTKLNVILEPVTIPENAQTVVPQASQSQT
FLSQPTQGKPFLGQTLQGQVLH--GQVMPAHTQKKPS-LPESSLRNKIKSFLQRINPKTK
GKGHEDS-MFSAAAKVAKTRKENVANSLAPAKSAVGRSKTEK-LTGYSKAQ----SCSAE
KLVGPAFLDGPQSLDNKPWLHSR--QAGSASALGH-LRHCPHHCPREACAPQPGHPP---
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVQQKSGNR--TSRARRT-SQEEAKKLGKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQISLTSQ------GPS------QGSS
GLEALSTSNVSFEH-SQD------------------------------------------
--PGSQKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNVEKSPTVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWDVGYPLYIYG--SICI-IALIIWQVKTS-RQKLRLGPDRSCC--------
-------------RCH--RRVQQKPGDG--TSRARRT-SQEEAKKLWKLLFLMKSQGWLP
QEESVRRILCADPCCQICNVMALEIKQLL-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------V-
-------------APEI--GLDNKMKL-------FLH-WINAEMKDRRHEESILLSKAET
VTQDRTKNFEKSPTVTKDHMWGATT-EKTTEDPEAQPPSE-EE----GLIFYDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SIFI-IILIIWQVKRSHH-ELSSEPKRSCC--------
-------------RCH--QKVRQRARGA--ASTVRRR-SQEEAEKPQKLLSIIKSQGWLP
PEGSVRRILCADPCCQICNSVALEIQQLLAGENNQISLTLS------GPL------QGSS
CLEMLSMSSMSLDE-CLE------------------------------------------
--FRSWHTRELSLA-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLRGPNTMASLRFEEPRAPLNQ-EM-MQS--NP--SLVQGNQG-Q
HHLNSQDSLLSP-NPET-LNPTHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWVHF
QRWGLPRRVEES---LRQLMPNPPLYYQSGND---QPVSFNLN--NISQVSLRGFETISL
QTWC-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPAFKA
-LSSP-HSLSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKNG
KVPKPPM-------KDPFLFN---KLSF--PQLLPKTSPQSAPHSSPLSPNWVSPSDHQQ
AQ-I--NV----PFLTLAECEALEWHLLQRQL--QLQWGWPAALQRSQHTQCF--MQHE-
-PCCKAQSPETMT-------TSQPGKSISVLTRELLFFPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIHLLLTSTNQQTVSYSSTA--LANVSIPQPVALEANGACDVL-SPTVAPVS
IPMPHLLTQAKAILQNHMDSKCGQIHQGKIPACVHRSRDCRIPGVLA--VAPLPCIPESQ
V-LELQAAS--DPDLHHKVMPW--MPTTLDQQ---QQFLPGTVTQHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRALAPAVT---SQSV-ITEMVPA-PVEI--PA
E-PLTQMVSFEEQCIS-----------------------LGPCPQGNNETCTDV--AKEF
QSVVPVKGTTE-TLPLESQT-----QPASPHSLQTHILTKLNFHLRKKALEI--QWGIPI
K--A-RESREQTAAA-PENISTQKSLENLNHQGEAL-LQELPIPP-DTLPAPNPEWVHL-
-KEQLANDLKA----VQQNQKQSSSKAVPHG-SAH----WVSKI------SQPSGDMTE-
-THMLCVRVEASVNKPSTEEPWGPEPQS-----PDKSKDPAHVPMLAGKREDPEETKAAR
DHREGDEGFGHSSTREERCPAEDQRPAGMLPNQTPRGFWRWSR-----SF-HLADPCQHS
SQHHPQLKLPQLPP-RFPGEKESD-NDLQDNQTELNVILESATIPENAQTVVPRASQSQP
FLSQPTQCKPLQGQTLQGQVLH--GQVMPAHAQKKPS-LPESSLRNKIKSFLQRINPKTK
GKGHEDS-MFSA-AKVAKTRKENVVKSLAPAKSPVGRSKTEK-PTGYSKAQ----SCPSE
KLVGPAFLDGPQSLDNKLWLHSR--QAGSASAPGH-PRHCPRHCPREACATKPGYPP---
-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVQQKSGNR--TSTARRT-SQEEAKKLRKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQISLTSQ------GPS------QGSS
GLEALSTSNVSFEH-SQD------------------------------------------
--PGSQKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNVEKSPTVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAPSA---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

-MLSPTFVLWEVGYPLYIYG--SIFI-VIVIIWQVKRS-HHELSSEPKRSCC--------
-------------RCH--QKVRQRARDA--ASTARRR-SREEAEKPQKLLSIIKSQGWLP
LEGSVRRILCADPCCQICNSVALEIQQLLVGENNQISLTLS------GPL------QGSS
CLEMLSTSSMSLDQ-SLE------------------------------------------
--FHSWHTRELSLS-SVTPTLSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLRGPNTIASSRLEKPRAPLNQEEM-MQS--NP--SLVQGNQG-Q
HHLNSQVSLLSL-NPET-LNRMHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGND---QPVSFNLK--NTPQVSLHRFETISL
QTWY-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPALQA
-LSGP-HPQSGGQDNDSGSDL--QQKYSQLFCGLPSL----HSESLVATFTGSQGLPKIE
NVPKPPL-------KDPFLFN---ELSF--PNFSP--------TSSPLSPNWVSPSDHQR
AQ-I--NV----PFLTLAEYEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCGKAQSPETTT-------ASQTGKSISVLTRELLFFPEHARKLLEFHI-QKQSIHHRW
GLPQKIQQSIQLLLTSTDQQTV SCSSTA--LAKVSISQPVALEANGACDVL-SPIAAPVS
IPRPHLLT QVKAILQNHINSKCGQIHQGKIPACVHRSWD----------LAPFPCIPESQ
F-LVLQTAS--DPDLHHKVMPW--MPTALDQQ---QQALPGTVTEHPKLLRVLSVEAIEK
LET-TLRHKHLAFLSGLPAL--YYVALPRALAPAVT---SQSV-ITEMVPS-PVEI--PA
E-PLIQMVSFEEQCIS-----------------------LGPCPQGNSESCTDI--AKEF
QPAVPVKGTME-TLPLESQT-----HPTSPHSLQTHILTKLNFHLRKKVLEI--QWGIPI
R--A-RKSREQTVAA-PENISTQKSLESLNHQGETL-LQELPIPP-DTLPAPNPEGVHL-
-KEQLANDLKA----VQQNQKQSNSKAVPQG-SAH----SVSKI------SQPSGDMTE-
-AHMLCVQVEANVNNPSLEEPCGPEPQS-----PSKSKDPAHVPMLAGNREDPEETKAAR
DHREGDAGFGRSSTREERRPAEDQRPAGMLPNKTPRGSWRWSR-----SF-HLADPCQHS
PQHHPQLKLPQLPP-RVPGEKESE-KDLQDSQTKLTVILEPATIPENAQTVLPQASQGQP
FLSQPTQAKPLQGQTLQGQVLH--GLVTPAHAQKKPS-LPESSFRNKIKCFLQHINPKTK
GKGHEDS-MFSAAAKVAKTRKENVAKSLAPAKSPVGRSKTEK-PTGCSRAQ----SRPAQ
KLVGPAFLDGPQSLDDKLWLHSR--QPGSASALSY-PRHCPRHCPREACATKPGHPT---
-----------------------------

-MLSPTFLLWDVGYPLYTYG--SIFI-IILIIWQVKRS-HHELRLEPKRSCC--------
-------------QRH--RKVRQRAREA--ASRARRL-SQEEAKKPRNLLSVMKSQGWLP
EEGSVRRILCADSTCQTCNAVTLEVQQLLAGENNQNSPPLS------EPS------KGSS
CLEVLSVSSVSLKQ-SLE------------------------------------------
--HSSWQPRELSLA-SVTPILSQLMDQKSLTQSAA--------QSTSA----VRVQD--C
WADDLQLGQEFQVSDELRGPETMASSRLQELGVSVNQQEM-MQN--NT--NFVQGNEC-Q
YHFSSQLSLLSL-NPEI-TNMTHPMALNM--VLPARLPFLSPKVLRL--LEVHVKKWMHF
QRWGLPRRVEES---MRQLMPSPPLYYQPEDD---QPVPVILN--NTSQVSVHRFEAISH
ETWC-SRMAGQPIQTFWVSEWPMRNPEE---RQYCQQI------PNPM-ALALPSPALKV
-LSGL-YALPGGQANVSGSHL--QEKYSQLFCGLPSL----HSESLVATFLGSQDLSKKG
NVSKPPL-------KRTFLLK---DLPF--HPLLAKTPPLSAPHSSPPSPNWGSPSDQQG
AQ-I--NI----PFLTPAECEALEWHLLQRQL--QLQWGLPAVFQRPQHAQSS--TQHE-
-PCDKAQAPETMN-------TSWPGRPVSVLTRELLFFPEHARRLLEFHL-QKQLIHHRW
GLPQKIQRSIQLLLSSTDQQTLPWSNTV--LANLSIPQPTALEATGNSAVF-SPTVAPVS
IPMPHLFAQAKAILQSHIDSKCGQIHQGKVPACVHSSWDYRIPGGLT--VTAFPCIPESQ
P-LDLQATS--DPDLHHKVMPW--MPKALDQQ---QQALPGTVTEHPKLPRALSEEAKEK
LET-TLWHKYLAFLSGLPAL--YYVALSRAMAPAVT---SQPV-ITEMVPE-PIEV--PT
E-PLTEMISFEEECSS-----------------------LGPCFQDNNGTCADV--AEEF
QPAAQVEGMME-TVSQESQA-----HPASPFSLKTHVLAKLNFHLRKKVLET--QLGIPI
R--V-RESMQQTAMV-PGDTFTQDCLGSVNNQGETL-LQELPIPP-DTPCAPELDCVHI-
-KEQLAIKLKT----VRQNHKQLSSKAVPQG-SAH----WVSKD------PQPSGDMTE-
-AQVLCVQVEASVNNTSLEELLSPEPQS-----PHKSKDSAQVPMLAEKIEDPVKLKAAG
DHGEGDAGFSLSSVREERHPVEDQRPAEMLLKKTSQGSWRQSD-----SF-HFAEPCPHS
PQHHPQPKLPDLRP-GVPGGKASE-NALQDSQTKLNVTLEPAMIPENAQAVVSQASQGQP
LLSQLIQGKPLGDQTLQGQVLN--GQVMLAHTHKRPS-LPESSLRNKIKSFLHRISPKTK
GKGHEES-TFSTAEKVAKTRKENVEKSLAPAKSPVGRTKTEK-PTGHSKAR----SPRTE
KPVGPAFLGGPHSPGNNLRLRSR--QPGSASVLGP-PRHCPRHCPQGACATQRGHPP---
-----------------------------

-MLSPTFILWDVGYPLCTYG--SIFI-IALIIWHVKRS-YRELRLGPNSSCY--------
-------------KCY--RRVKQRSRDR--TSRV-KRTSKEEAEKLQKLLSVMKSQGWLP
QEGSVRRLLCSDPSCPICNAMALEIQQLLGGENKQTSPVPL------RPS------QSFP
CLEALSSSKGLSDK-SPE------------------------------------------
--LCSQHSRDISLASS--LTPSQSTDQKSSTQSAA--------PSTGD----ANIQY--Y
CPDHEQKQG-PQGSNVSPDAGTLSSSSEEELGVPANQQKKK--K--SK--KLVLKNE-E-
-------------PPEA--EAENKMTF-------FSH-WVNPEVKCERLEEPIVLSKSEV
EAKPKTEEPKKSQTPIRDHKERANK-EQTMKDRKAKPLSAKKT----N------------
------------------------------------------------------------
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-----------------------------

MILSHSQCGC-EGQMRLGPGEHLIHV-SEHCLWSLQS----PLP-RRPSACC--------
-------------RRFLNPLPLHVTLSP--GFSARRL-SRKEAEKPWELLSVMRSQDWLP
QEGSVRQLLCADPCCKICNATALEIQQLMVGENTLTSPISR------RPP------QGSS
CLEVLSASNVSFEQ-SLE------------------------------------------
--HHSPHSKDLSLP-SATLT----VSQKSLIQSAA--------RSAST----VSIHDYDY
CAEHLKKRQGFQVPDVPRVPETMFSSRPEEPRVSVNLQEM-IQS--NL--NLVYGNQG-Q
QPLNSQVSLLTL-NREI-TTLTHPVALHMVTVLPAHLPFLSPEVLRL--LEVHVKKLMHF
QRWGLPRRVEES---LRQLMPNPPLFYQPIHN---QPVSFIQN--DTSQLSVEKFGTISY
QNWG-SCMAGQPTQAFWVSEWSILDPEQ---RYYYQQI------PNHM-ALALSSPSLKE
-LSGL-YLMSRQQANDSVGHV--QPKYSQLFCGLPSL----HSESLVDTFLDSQGLSMNE
TMSKSPL-------KDPFLFK---ELSL--FPLLPKTPHQSAPLSSLSSQNWILPSDHQQ
SQ-I--NV----PFLTLDECEALEWHLLQRQI--QLQWNLPGVFQRDQRTQSP--VQYK-
-PCDKAQSSETVK-------TSCPGQPSSDLTKEL-LFPQHARRLLEFHL-QRQLIHHRW
GLPQKIQQSMQLLLPPANQQTVSWRSSA--LGSVNVPQPASLEATGADDPF-SPTLDLVS
DPMPHLFDQAKAVLQSHIDSKCRQIDQGNVPSCVYSSWECIIPGHLK--KTSFTCIPESK
S-LELQAAT--DLDLEQKFITW--MPVALDHQ---QQASPDAVIEHSKLPLALSKGTIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRAMAPAVT---SQAV-ITEMVPE-PVEL--PA
E-PLIQVTSPEEQGLS-----------------------SGPGFQDASEACADI--ADES
QAEVQVDGTTE-TVPIESQT-----EPARLYSLGEPILAKLNFHVRKKILEI--QLGIPI
K--A-RESREQTVAI-PENICTQESLGSLNNQGKTL-LQELPIPP-DMPCAPDPEWLHF-
-KEQLATELKA----VHQKHKQLSSSLVPHD-AVH----WASKI------SQPSGDMTE-
-SQVLCVQLEASVSSPSLEEPWSPEPQS-----PDKKKDSAHSPTLAEKIEEKGKPKLSG
DHGEGDAGFSLSSTREKSQSAEAQRPERMLLNRTPCSPWRRRH-----CI-HLDAPCQPS
PQHHPQLKLPELSPR-DPGGKGSEKNDRQDNQTKLNGILKPAKVYKNAQPKVPQVSQGQP
FLGQLILDKPLQGQTLQGHILQ--RQMMPGHTHKRPS-LPESGLRNKMKSFLHRINPKTK
GKGNEES-MPSTSKKVPNTRKENMEKNLAPAKSPKGRTKAEK-TRGGPKPQ----FPPTE
KQVGLAFLDVSHYPDHKLWHHSHSHQLYSASVLGI-PRHCPRHCPRVARATQPGNPPNTQ
LSPQRETLACSRRPSAVRRLCSLSNICIP

-MLSPTFVLWDVGHPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVQQKSGDR--TSRARRT-SQEEAKKLCKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQISLTSQ------RPS------QGSS
CLGALSTSNVPFEH-SQD------------------------------------------
--LGSPKSKELSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--SLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNVEKSPTVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAPSA---
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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-----------------------------

-MLSPIFVLWDVGYPLYTYG--SIFI-IILIIWQVKRS-HHELKLEPRKSCC--------
-------------WRH--RKVKQRARDA--GSRARRL-SQEEAEKPRKLYSNMKSQGWLP
QEAGVRRLLCADPCCQICNDVALEIQQLLAGENNQTSPNSQTSPTLSEPS------QGSS
HLDILSVSSISFEQ-SLE------------------------------------------
--LHSQHTRELSLA-SDTPTLSQLMDQKTSTHSAA--------PFTSS----IRVQD--Y
WVDHLNLGQGFQMPDVPRGPDSMTSSSFEEPTGQVNQQDM-IQS--NP--NHVQGNQD-P
HHLEPQVSLRPL-NPEI-TTLTHPVASDMASVLPANMPFLSPNVLRF--LEVHVKKWIHF
QRWGLPRRVEES---LRQLMPNPPLHYQPGNN---QPVSYILN--NTSQVSVHRLETISH
QTWC-SCMAGQPIQTFWVSEWSTMNPKQ---RHHCQKI------PDPM-ALASHSPALKA
-LSGL-YPPPGGQASDLDSYL--HQRYSQLFCGLPSL----HSESLVATFLASQALSKNE
NLSKLPL-------KDPILLK---DLSF--LPLLPKTPPQSTPPSSPPSPNWVTPSDHQQ
AH-IQNHV----PFLTLAECEALECHLLQRQL--QLQWGMPAVFQRSQHAQSP--MQYE-
-PCGKTHSPETMT-------TSWPGKPVSVLNSELLFFPEYAQKRLDFHL-QKQLIHHHW
DLPQNIQQSTQLLLSSTDQQALSWHSTA--LATSSVRQPVALEANRAGNEL-------ST
IMSPHLFAQAKAILQSHMDSKCGEINHGKLPACVYRSWDCRTTGELA--VAPLPCIPESQ
P-MVLQATS--DPDLHHKVMPW--MPTALNQQ---QQALPGPISRHPRLPQALSEGAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRAMAPAVT---SKSI-ITERVPG-PTKI--PE
E-PVTQIISSEEQYVS-----------------------LGPSFQNNSETGADT--AEES
KPAVPVEGTME-MLPLESQT-----HPAILHSHKTHMLAKLRFHLRKKTLEI--QWGIPI
R--A-QESREQTAAV-LENKSTQESLGSLNNQGETL-LQELSTPP-------DPEWVHH-
-KEQQIAELKA----VQQNQKQPSSKAVSHG-SAH----CICKT------SQPSGDMTE-
-AQVLCVHVEASVNTTSLEESWSSEPQS-----PGKTKDPGKVPTLAEKREDPEKPKAAG
DCGEGDAGFGLSSTTEKRHPGENQRPAGMPLNKTPHGYWQRSH-----SF-QFADPCQHS
PQHHPQLKLPELPP-GVPGRKESE-NDLQDSQTKLHATLKPARIPENAQPVVSQTSQGQA
FPSQVFKTKPLQGQTLQGQLLH--GQVIPACTHKQPG-LPEANLRSKARSFLQRINPKAK
GKGHNDC-IFPIAEKVTKTRKENVEKSPAPAKSPMGRPKTEK-PTKHSIDQ----SSPTK
KPVGQASFNNSHCPDNKLRLRPR--QSGSASVQGH-LHHCPRHYPRVDRAT---------
-----------------------------

-MLSSVCTLWDIGYPLCAYS--SIFI-IFLIAWQIRRS-YQGLRLEPKKSCC--------
-------------RHH--RKVRQRARDA--ASRARRL-SREEAEKPWELLSIMKSQSWLP
KEERVRQLLCIDPCCQICDAATLEIRQLLESEQSQISPALL------GLP------QDSS
CLEMLTISSETFEQ-NVE------------------------------------------
--LHPRPSIHLSLA-SETSTLAQLTDHL------A--------QPPNA----AGVHQ--C
YEENLQLEQKFHLADMPMVPETMVPLRFEDPVVLMIEKKIT-PN--KP--EVDQESQD-H
HHLNSSVSLLSL-DPEI-TNLSHTMSLDMDAVLSSHMPFLSPQVCRL--LEIHVKKWIHF
QKWGLPRRVEES---LRQLMPDPTSFCQFRKT----PFSSCLS--SGSELTMSHH-----
-TKS-LCWADQPTQACWVSEWSVVSLKQ---RKHWHQI------QAF-----LPSREAEH
-LSGF-YPPPKAQANDSGSNF-QSEYYSQLFCGLPSL----HSESLDASSVSSQGGSESK
TVSKPSS-------RDP--TR---ELSL---PFLLQTPHQSAPPT-FSSPNAKTPYEHKG
AG-M--DV----PVLTLAECEALECHLLDRQV--KLRWGLPAVVLRNRDTRSH--VLCE-
-ARGKT---KTVK-------TTWP---FWHCTRESS-FPEHARRLLEFHL-QKQLIHLRW
GLPQRIQRSIHLVLSSPGQQPRSCSN-G-ALPNVSILQPGDPEADGSGDTF-AVAVDRGS
VPTPHLFSQTQAMLKTHVDSKCGQIHQGKVPACVQSSWECRIPRSLSV-GASFSNIPASR
H-LELQAKSNPDLQHTAVSQEA--EPAALDQE---KQASSSALIEHCKRPQALPEETVKK
LET-TLQHKYLAFLSGLPAL--YCVALSRPSSPAIT---SKPR-TAERMSG-AVKS--PP
E-TLPHTTSLEGS--------------------------LDPCPRDDKEASADI--AGQV
QPEVQVAGGTG-KR-----P-----PD-SPNLLSTLILERLNFHLKKKVLAM--QFGIST
K--E-REYKELAIAD-LESESIREFLRSLSIPESTA-LPQLPNSG-DSPPAPDANRVHL-
-GKQPATAGQA----LCYKQKQPSSKAVPYG-SAQ----WGSKA------SQL-RNMTE-
-AQGHCVQLETSGEKPNL----------------------------------E-KPKAVW
DLEEGDAGLGLPLTSGKTHHDRDEELEKRPPPETPQGSSEQRP-----RS-H-----PPS
PQDLSEFEFPDPPP-EVLMVIDTT-QNMQDSLTKVDAIPEP--------PVASKTSQGLP
FPCTPTQGKPFRGQAWQDHISQ--RQVTPASPHASP-SLPETGLKNKMKSFLHSMSPKIK
DKTHMEPH-VSTPRKVSKPSQENANKGLPQAKNPTKKTKTEN-CRM-PKAQ---PA-SSE
RPVVTSFLTAPHILDSKLGPGSR--QHGSVSGPGQ-PRHCPQHCPRLARATQQGN-----
-----------------------------

------------------------------------------------------------
----------------------------------------------------MKSQGWLP
KEGSVRRLLCADPSCPICNAVALEIQQLLSGEKTLTSPSSS------GPS------QGSS
CL--------SLEQ-SQG------------------------------------------
----SLHSKALSLP-SVTPTKSQLTDQKCLTQSAAQS------TS-------VSIQD--I
QGECLQRRKGYQVPDVSRDTGALSSSSE-GTRTPVNQQDKR-KS--YP--VCVLEKQ-G-
-------------QLPL--NI---------------------------------------
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-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-IALIIWQVKKS-RQKLRLGPNRSCC--------
-------------RCH--RRVQQKSGNR--TSRARRT-SQEEAKKLGKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNVMALEIQQLLAGENNQISLTSQ------GPS------QGSS
GLEALSTSNVSFEH-SQD------------------------------------------
--PGSQKSKEFSLA-SVTPTLSQLMDQKSLTQSAA--------QSAGA----DSVQD--S
WADHFQRGQRSQVPAVSQVMGSLS-SNFEKPGIPLSQQERK-KN--NS--KFVLENQ-E-
-------------APEV--GLDNKMKL-------FLH-WINPEMKDRRHEESILLSKAET
VTQDRTKNVEKSPAVTKYHVWGATT-EKTTEDPEAQPPSTEEE----GLIFSDAPSA---
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-----------------------------

-MLSPTFVLWDVGYPLYTYG--SICI-I---------S-RQKLRLGPNGSCL--------
-------------S-P--SRLKQKSRDT--TSKARRT-SQEEAKKLWKLLFLMKSQGWLP
QEGSVRRILCADPCCQICNAMALDSQQLLASENSLIFLTSL------GPS------QGSS
CLEALSMSSTSFEQ-SQD------------------------------------------
--LDSEKSKEHSLA-SVTTTLSQLTDQKSLTQSAT--------ESASA----DSIQD--S
WADHFQQGQGSQVPAVSQGMGSLS-SNFEKHGIPLSQQESK-KN--NS--KFVLENQ-E-
-------------APEV--RLDNKMKL-------FLH-WINPEMKDQRHEESILLSKAKR
VTQDRTENTEKSPTVTKDHVWGATT-EKTTEDPEDQPPSTEEE----GLIFHDAP-----
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-----------------------------

-MLSSACSLWDISSPLCTYS--SIFI-IFLIAWQVKRS-YQGLKLEPKKSCC--------
-------------RRH--RKVRQRARDA--ATQARRL-SQEEAEKPWNLLSIMKSQSWLP
TEGNVRQLLCVDPCCQICDSATLEIQQLLESDKSQISPALL------GLP------QDSS
CLDMLPISSVPFEG-NME------------------------------------------
--LHSRHSRHLSLA-SETPTLAQLTEHL------T--------QSINA----VSVQE--C
WADDLQLDQKFDLADMPIISETVVSSRLEEPVVLMIEEKIM-QS--QP--KVVQESQD-Q
HPLKSSVSLLSL-NPEI-TNLTHSVSLHMDSVLSSHVPLLSPKVRRL--LELHVKKWIHF
QKWGLPRRVEES---LRQLMPDPALFCRSRKH----MLSSVLS--SASEVPMNKAGTISQ
-------------HTCWVSEWSIINSKQ---RMHWHQI------YEY-----LPSHE-EH
-LSAS-SPPTRAQDDDSGSNLPENEYYSQLFCGLPSL----HSESLDVTSLSIHSVSKNK
NVPKSSS-------TDPRHTK---ELSL---PFLPQTPCKSALPSSLASPDVKTSHEHEE
LQ-F--LV----PFLTLAECEALERHVLERQV--KLQWGLSGVFLRNQYRQRH--TLCE-
-PHGKA---KTVK-------ASWPRNAFSYPTRKFS-FPEHVRRLLEFHL-QKQLIHIRW
GLPQRIQRSIHLLLSSANEHALSCSRSR-ALSSVSIPKPGSPEADGSGDRF-ASAVDKGP
ILMPHLFVQAKAMLKSHFDSKCDQIHQGKVPAQVWSSWECKIT------TVPFSWIPQSQ
H-LKLYPESKSNA---------------D-QE---KKALSGTLIEHCKRPQALSKETIKK
LET-TLQHKYLAFLSGLPAL--YCVALSRPTSPAVT---SQHR-TTEMMSL-PVKS--PP
K-ARTSSK---GP--------------------------FESCTQDDNKASANI--TEEL
QPEVQVEGKTD-CQ-----T-----HD--IHLLNTHILAKLNFHLKRKVLAM--QFGISE
K--E-REYKELAIVD-LESESIQEFLRSLSIPESTE-LQKLPDSG-DLPPAPDASTDHL-
-KKQPATEVQA----VCHQQKKPSSEAVPQG-SVE----WDSKV------SQL-RNVTE-
-AQVPCVQMETSGEKPNLEEP-------------------------------G-KPKAVG
DLGEGDTGLGLSPTSEGTHRDGDQEPEEGPVHGTPEGSSQHSH-----SF-HPEDPCPPS
PQNTPELEFPDPPP-EVFMEREPE-HDTQDSQTKANV--PQ--------PVASRASQGIP
FPRPLIQGKPFRVQTRQDRISRGQGRVMPTSPQASP-SLPEAGLKNKVKSFLQSINPKIK
GKTHVEPM-VSTPATVAKTSKENVGKGLPQAKSPTQKAKAEN-CRG-PKAQ---ST-PAE
KSVIASFLTAPHILDSKLRPNPG--QHGSVSVSGQ-PRHCPRHCPRLAYATQHRN-----
-----------------------------

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-------------------MPDPTLFRRSREN----PSSCTLS--SSSKVIEDRTGIVSH
KTSS-LYSAGQPVQTFWVSKRPVINLQQ---GRPWHQI------HTC-----LPSHEGEH
-LRNF-YPLPRAKANDSGDNL-QSEYYSHLFCGLPSL----HSESLDVTYLSSQGTCKKK
DMSKPST--------DTQPSG---VLSG---LFLPKTPCKSAYPSSPTSLNGKTPCEREG
AQ-I--TV----PFLSLAECEALERHLLKKQL-SKLQWGLPTLLLQNQ---RR--MLCE-
-APSEA---KTVK-------TSLARKPFLHPTRD-I-FPEHTVRLLEFHL-QKQLIHLRW
GLPQRIQRSMNMLLSSTDPQSLPCGS-S-SLPNVSISQPGKPEANGPGDMF-SLTAGKGT
IPMPHLFAKTREMLKSHVDSKCEQIQEGKVPAQVWKSWECKIPGSLAT-VAPFPWIPQGQ
C-RKLQAESKSDPDLLHKVVPW--KPKTLSQE---TQTLSGTLFEHCKKPQSLPKETIKK
LET-TLHHKYLAFLSGLPAL--YCVALSRPASPAVT---SQPR-LREKMPK-AVKS--PS
N-ALTQIT----P--------------------------LEPCTQDDSGVSADT--AEEF
QPGAEADRRTE-KVPAESQP-----PPCRPYPINTHILAKLNFHLKKKDPSN--AVWDF-
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-MLSPTFVLWDVGYPLYTYG--SIFI-IILIIWQVKRSHH-ELSSEPKRSCC--------
-------------RCH--QKVRQRARGA--ASTVRRR-SQEEAEKPQKLLSIIKSQGWLP
PEGSVRRILCADPCCQICNSVALEIQQLLAGENNQISLTLS------GPL------QVSS
CLEMLSMSSMSLDE-CLE------------------------------------------
--FRSWDTRELSLA-SVTPILSQLTDQKSLTQSAA--------QSTYA----DGIQD--Y
WADHLQLGQEFQVPDVLRGPNTMASLRFEEPRAPLNQ-EM-MQS--NP--SLVQGNQG-Q
HHLNSQVSLLSL-NPET-LNLTHPMALHM--VLPAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQSGND---QPVSFNLN--NISQVSLHRFQTISL
QTWC-SCVAGQPIQTFWVSEWSTMNPEQ---RHHCQQS------PNPM-ALALPSPAFKA
-LRGP-HLLSGGQDNDSGSAL--QQKYSQLFCGLPSL----HSESLVATFMGSQGLPKNG
NVPKPPL-------KDPFLFN---KLSF--PQLLPKTSPQSAPCSSLLSPNWVSPSDHQQ
AQ-I--NV----PFLTLAEYEALEWHLLQRQL--QLQWGWPAALQRSQHTQCL--MQHE-
-PCGKAQSPETMT-------TSQPGKSISVLTRELLFFPEHARKLLEFHI-QKQLIHHRW
GLPQKIQQSIHLLLTSTNQQTVSYSSTA--LANVSIPQPVALEANGACDVL-SPTVAPVS
IPMPHLLTQAKAILQNHMDSKCGQIHQGKIPACVHRSRDCRIPGVLA--VAPLPCIPESQ
L-LELQAAS--DPDLHHKVMPW--MPTALDQQ---QQVLPGTVTQHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRALAPAVT---SQSV-ITEMVPA-PVEI--PA
E-PLTQMVSFEEQCIS-----------------------LGPCPQGNNETCTDV--AKEF
QSVVPVKGTME-TLPLESQT-----QPASPHSLQTHILTKLNFHLRKKVLEI--QWGIPI
K--A-RESREQTAAA-PENISTQKSLENLNHQGETL-LQELPIPP-DTLPAPNPEWVHL-
-KEQLANDLKA----VQQNQKQSSSKAVPHG-SAH----WVSKI------SQPSGDMTE-
-AHMLCVRVEASVNKPSTEEPWGPEPQS-----PGKSKDPAHVPMLAGKREDSEETKAAR
DHGEGDEGFGHSSTREERCPAEDQRPAGMLPNQTPRGFWRWSR-----SF-HLADPCQHS
SQHHSQLKLPQLPP-RFPGGKESE-NDLQDSQTKLNVILESAAIPENAQTVVPQASQSQT
FLSQPTQGKPLQGQTLQGQVLH--EQVMPAHAQKKPS-LPESSLRNKIKSFLQRINPKTK
GKGHEDS-MFSA-AKVAKTRKENVAKSLAPAKSPVGRSKTEK-PTGYSKAQ----SCPSE
KLVGPAFLDGPQSLDNKLWLHSR--QAGSASAPGH-PRHCPRHCPREACATKPGYPP---
-----------------------------

-MLSPNFVLWDVGYPLYIYG--SIFI-IILLIWQVKRS-HHELRLEAKRSCC--------
-------------RRH--QKVRQRARDA--ASTARRL-SQEEAEKPQELLSVMKSQGWLP
PERSVRRILCADPCCQICNAVAQEIQQLLMGENNRKSPTLS-----RSPS------QVSS
CLEILSVSTISFEQ-SLE------------------------------------------
--FHSRHTRELSQA-SVTPTLSQLTYQKSLTQSAA--------QSTYA----DGSQD--Y
WADHLQLGQEFQMPDVLQGPNTMASS-MEEPRAPLNQEEM-MHS--NP--SHVQGNQG-Q
HHLNSQVSLLSL-NPET-LNLTHPMALDM--VLAAHLPFLSPEVLRL--LEVHVKKWMHF
QRWGLPRRVEES---LRQLMPNPPLYYQPGNG---QPHSFNLN--NTSQVSLHRFEIISH
QTWC-SCVAGQPIQTFWVSEWTVMNPEQ---RHHCQQS------PNPV-ALALPSPALEA
-LSCP-HPLSGRQNNDSGSDL--HQKCSQLFCGLPSL----HSESLNTTFVGSQGLSKNE
NVPKSSL-------KNPFLFN---KLSF--PHLLPKTPPQSTPPSSPLFPKWVSPSDHQR
AQ-I--NV----PFLTLAEREALEWHLLQRQL--QLQWGLPAVLQRSQHTQCP--MQHE-
-PCGKAQSPETMT-------TSQPGKSISVLTRELL-FPEHARNLLEFHI-QKQLIHHRW
GLPQKIRQSIQLLLTSTDQQSLSCSSTT--LANVSIPQPAALEANGACDVAPSPIVAPVS
IPTPHLLTQVKAILQNHIDSKCGQIHQGKIPACVHRSWDCRISGGLA--VAPFPCIPGSR
L-LELQTAS--DPDLHHKVMPW--MPTALDQQ---QQALPCTATEHPKLLRVLSVEAIEK
LET-TLRHKYLAFLSGLPAL--YYVALSRALTVPVT---SQSV-ITDMVPG-PMEV--PA
E-LPTQMTSFEDHCIS-----------------------LGPCPQDNNKTCTDV--AEEF
QPAVPVKETTE-TLPLESQA-----HPASPHSLQTHILTKLNFHLRKKVLEI--QLGIPI
R--A-RESREQSATV-PENIFTQESLQSLNHQGETL-LQELPIPP-DT-PAPNPEWVHL-
-KEQLANEWKA----VQQNQKQSNSKTVPQS-SAH----WVSKI------SQPSGDMTE-
-AQVLCVQVEANVNNPSLEEPWGPEPQS-----PNKSNDPAHISMLAGKREDPEETKAAR
DHGEGDTGFGLPSTREQRPPADDQRPGGMLPNKTPRGSWQWSR-----SF-HLADPCQHS
LQHHSQLKLPQLPT-GVPGGKESQ-NDLQDRQTEINAIFELARIPENAQTVVPQASQGQP
FLSLPTQSKPLQGQTLQGQVLH--GQVMPPRTHKRPS-LPESSLRNKIKSFLQCINPKMK
GKGHEDS-MFSAASKVAKTRKENVAKSPAPAKNPVGRSKTEK-PPRHSKAQ----SRPAE
KLVGPAFLDGPQAPDNKLQLRSR--QPSCASASGH-PRHCPWHCPRVACVTKPGHLP---
-----------------------------

-MLSPTFLLWDVGYPLYTYG--SIII-IALIIWQVKKS-HQELRLGPKRSCC--------
-------------RCH--RRVRQRAKDK--TSRGKRL-SR-EADKPWQLLSVMRSQGWLP
KEGSVRRLLCADPSCPICNAVALEIQQLLSGEKTLTSPSSS------GPS------QGSS
CL--------SLEQ-SQG------------------------------------------
----SLHSKALSLP-SVTPTKSQLTDQKCLTQSAAQS------TS-------VSIQD--I
QGECLQRRKGYQVPDVSRDTGALSSSSE-ETRTPVNQQDKR-KS--YP--VCVLEKQ-E-
-------------AAEG--GLGNKMKH-------FPH-WINPEVKGQRHKESILLSKDET
VPKTMTKKVEKSPPLTKHPVRGAKL-ENKT----------EEE----SMTFFDAPQSLDN
ELKQQS---LQSRHSWL-LCLPHNS------SKHCPQLTCATQPENPPQVSALLSA----
--EGT-GLHKEK-----------TQCRKKEFLVSSAS-------------------P---
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Query Results

"ENSGT00840000129843"

ENSGT00840000129843