ENSGT00840000129812_2 : Linker Region Query Results

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-RLSDQDEEGKTEKKCIISDPSFSMVTVQQEDSGITWETSSSRPSTPWASEESQTSGVCS
LEGSTL-NSPPGNVSFILDEVKKVRKRKPK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
ANKTSTPLISESQELTTQKDKSST---GAYDKMRK----KKSTSSTPPITGAIYKEYKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKE--ASISLEPES
GNCDLKVVSKTGKS-----VAQSIEDV----------------KVKELAPPWRDAFSKG-
----------SKSLT---------SLFSHEDQ-KKTYDDFPLRAA--SAAQ---------
-----------------HTASSHTSHAIAE---RESQLSPPRVV----------PRLLVD
EAKPREMKPSFLTPD-TSVATF--LETAKEESEADSQEIVIAEPDSSASPPVLDEVKTED
MSSVDHSIS------LEAEKGSLESGAPGLTASIQED----FSPERDKLDLTSRERVEPV
TDQLTPP-----------------------------------------------------
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------------------HLII-------------KGGKGETVPEPSISLFEPLVLEEPE
KEEIEMPLPMAATPEPEDSNLVE-EEIIELDYPESPSVSEEPFPPRL-APEVEE------
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---------------KE-ETPLPLLTTS-------------TPEHVTLSEEERE----EN
ESVSTDSAFVSEYSAP----------QDWNYELEK----QEA------------------
----------------EPVSLPHVKAVSEHAVLS---------------EEEDDKFEPSS
PTSAS---I--------------------------------------FVSPSTTEKTLEC
QSPLFSAVTPEPMILSGEEASES-----GHYTPDSTSAS--------------EYLVPSQ
ATEESP--KKTVDLKSPLKS--QGVSEPLILSEEENEDPGLCSP---EVASLSERSVSPH
TTEGTSEGQAPLLSA-VTSEHAILSEEEN-LGNEGVTRD---------------------
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----------SALTFQNAVPPNVRQESP-KNIIDDVSLLKSEGVSEHKTVLEE-EKEDAG
FYTPEV-ASLPEGF-LPP--------STTEGTPECQVPRL-----SVAPPDHVVLSEEET
V-----EMERYTPSST---------SAS-ELSEPPYATPESQEEEIVHTSPLNLK-----
------------------------------------------------------------
----GSSSPMIFSEEE--QEDIGPFSPDSAFVSEFSFPPYAT--TGKREFECDSPICLTS
PSEHTILSDEDTEETELFSPDSAS--QASIPPYRIPEMNKKEIEPDSLLTAMAASGYPRF
SEADEEEI-APTTT---TPV-PEHLS--SLQKQRAEP--SVSA--PEDLSQLPSTN--EA
EKAEIKPDAQTTSASVSEYLILAQK-------QRTQTYL-EPEPEDSIPPSLT---S---
------------DSERGETKSSS-SLAAAP----AVKEVPTVKEETKPVLPASQCSVSPD
SV-------------------HAIKKEQEPQTSLTPK---------SADEQM--------
-ALLKVE--------------SKEEIVPDSQEAIAHVL------QD---QEMEPQPPN--
--VPDSGMKDSVLPDL-AD-----------------------------------------
-------------------EPKKDVKPNLAPTLTS--ELEQRRLSEKEP---EVTKPYSP
LKETSLSRP----------------------------EISS----------VVKTEVKLD
SKVTGTP----RVLRSASPGVEQEVE---------------------------------H
GPPVP------EFEFSALS--EEIKKEIEPSSSITATS-ETK---------HDS------
------------------------------------------------------------
---------------------------------------NLTKLAKEEIPKNL-------
-----------------------------------PLTTPIEH-QVLTKGEK-------S
ELGSGLP----------------PV------DEHSLFKE-DKVAI---------------
---KA-SPSPTETAASQYPAW--SEVE-----KEIK-------FDLPASISSISEHSVLS
KVETEDIKPGLAITKTLSSQ------------------HSDVSKEARVE------DKQDL
SFPTVLDSEYLDLSQKKISVSASEMSGPEHVPSLSLGGEIKKTETELPSSQNMSPAPKYI
VPKGKDEVTASSVPELKHLTSEDLASTFLTFSGDKREQAVETPSVIQGDFRSEKAGLALA
Q-----LSLEPEKRDKTHPVSEFPDTGNAGSEFAGDVNRQSGSIQTEHIKSPLPETENSA
LEKGLPELRSRGEGKEENRELHV--STTV-PKISEVSSYLREEPQIQEMKSLSAKVVSLG
SREAFTSQLEGDSLEEFQSHTLSSKGLSEELNRSADFKKEEKQEISPLQPAGNLKAQETE
DTVTKP-NETDQPN--SFHVLQSITEPSNITSSDLFVQ-QKPEE----AFVSDQAATLPE
IS-----RSFADKQDLGIKQVLFMKENLPLEESKLFMTTEPTNVRETHMKEALISPKD-E
NWMLKEPEGDLVSHHEERAMESVQLDHSGT--NDLMTGQLKPAL----------------
-PEKDHMPEIRKQILPPSAEEPHIAFQEPVSTLDTSRDNVETLATETYSSEDIKL-APKP
KSLVPAGNVERSEAEGKQTLSFVGGESLVVEKANTEISRPCKE-GSQEEIKTPYEGGLQ-
KPVSGPSVEQVKSETPPSLVKAARALAEEAEPAL-GV---EKEAH-GRISPLPGEKPLEE
SNVVQPKVADDANE-----RGKPPSEV-KAPTQIKP-LSSTQE-NEEPQPLESPEVIQKP
PKQQKAV-EPSISEEKGKKGISSFTSWVSSFFFRSSTLDNEVAEK-EDL-EAQPSPSEEK
TVTVI-DSEGPA---P-ADVHGTEKPVSHLFLEAKRETASESAGSLVKSGEHQDFK-EKP
ALLSDVEVSPQPKSN---FEASSDDYGKKEVLDYSGEMDLTSVVTSADGEGHLRIQSDSP
MGEKSIMEEAKNAVPLHVTDSKRLQKP------------EISPRSKWNISILKEEPR--S
DQ-----------------------------------------------------KEKTL
FLVDATDKVPQQPESGSSSFASKDI------------TEESEKLESIILPGEEPKGSLID
LGEDRLGKEMPKPVSLKISEEEVKLRSVSPAEEKGNLGMRSYSLAEKKVLAEKQEIA-AP
LEHRDINEIEKAKIIHGPSPVKLEEPKAATVLQQVYQN-EDHKERYKIIEEEK-------
G---EEKEERSHAFSEG-REQEIQPYSISIAGHPPEESDI------------------S-
--FHLTLG-E-----TQPFSLVKTTEAAETLET---------------------------
-----TISEAYSEIRETKAVGSQPHPLEEREVLVEETKAFLP--------VDLPYHDEIN
EPSLPKEGNLVLEK--S-------------------------------------------
---------------------------------------------SRDVVTHSEEKGQ-V
IVSELPKAGSVGTTEE-SKQG----------SPSKESERILDRPFGETKSLETPSYLLSS
VKP-----QTLTSEASPEVSPEKKQELPWSEV-----------TPH--------------
---------RPTVHTTQTSKDQTS-----EMFEQPVLVSK----HHLEAVEDSQVYEPCP
SASSNYA-QFI-----TNASTISADEVV-----SKEPEDTSVRDEEF-------TVTSKP
AGL---SEEQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQDKLEYLEEKISFKPI-
LLRDESEEVACHKTLQ-SKL---EDSDIKVISLKE-DQQKEIH---------TTKEEIPT
DSETGDLAFNQPTS----PD-EEDYFEKYTLIDYNIFPDPEKQSAPWKLE---AGLSKEV
PEETVSFPEHSEEGALEHEYDLV-KLDESFYGLEKDYSKL-SDPETQKSLVIQKLTD--R
DAP-KSTDRDVGSKSPGMPLFDEEEGVLSRTQIFPTTAKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTCVTEKD
QGQGLEEKPIDKDDSYQPITA--EGEIW---GKFATIGREESLEEKQ-KAAYREGESVGH
METLDNVA-MQRKAPITEEVRVVTQR-ISYAVPFEDTHHVLERVDET-------------
-------SSQT------NE------AA---------NANPEVSLNVPVQVSFPEE-EFAS
GATCMQEILQEEPQIMVPPEPSED--WVRSSPVQDEYEFAESLNYEVVTQ-DTLSED-LY
SESTPEDVL-SQGKESFEHVS--ENELVTEAEQRKSAEQKELDIEMAEQDQLLSE-LVTE
KEQKEMKTSQIDTYCYTCKSPISAVDKMLGTHKDHEISTLDTAISAVKVQLADFLEDLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKRKKM
EFLHDQMVHFLQSMDTAKDTLETIVREAEELDE--TVFLT----SFE--------EINER
LLSAMENTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NDLVEEYRVTVKESYCVFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPAS--PEAT
ETYTLEYCRQHAPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTRAIGTRFLLLRETAHPALQISSNGTVISFAERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGVCSSSAVQ-AGALAQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYTTQRLLFINAETGQMLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSARQK

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--------EQKDLFNIISEGYEILNIHAPTHISSVDQEESKHMPDKLEYLETNPSFRRK-
SVEDGQRALTSGRTTE--------ISESSVLEKTASHELIELET------EETQQENLPL
P-EDNNCAKLDPNN----GTGDMDYFEKYTLIDDKSPVKPQFERP-ISLS-PVTEDPNEP
MEEVKSFEESTEVDTLE-EFSLLEDLDEVFYGTIKGESKIQSYTDASKSLPLQKSID--S
SSK-SITNVEDECKSPGTPLFDSEEGVLERSLLFPTTVAAINPELLEEPPALSFLYKDLY
AEAVGEK-TKDETPSDEESGNSNASFPSRNSDTDDGTGMYFEKYILKDEIPKDDSENKQE
QGSGDVQYVK--------------TEVL---YQSSQSKKDTVIKWIIRELPYQDAST---
---------NQEELQIHRHFPQWHRMVPYVRAPTGKLTRAVKSTKIQ-------------
-------SSSG------YQGAAYQEASTKQEELQDTTAFPQMEKYVPYVR-APTE--DSV
DDQFTQEHLSCVPTIQQTENPDLQ--REE-QHGDIYEDFAESMDYDVITQEELLQDE-IS
SQFTHEELL-FEDRDSFDHAA-DSYEFVNEPEQRTPIELEDSGFVVMYPEKSATNIPQVE
SPQRELKKSQVDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDQLSKLLTALEE
KSMKIEEFVSDIELRFNSVEENCKKNADLLEKQNEEMLKKVVAQYDEKSENFEEVKKMKM
EYLYEQMVNFQQTVDSAKETLETTVKETDEVDG--FVFLNV-----------NTCFLPIR
LLSAMDTTLSLEKVPSAFSLFEHFADSPGQSNQHSLQHVAVPQTPTVIPQEPNSATSTS-
-IAVYWAVNDGDTIDCFQVYCTEELQASKDA--GALVEEYRVTVKESHCILEDLEPDRCY
SVWVMA----VNGTGCSLPSEKAIFKTAPAVPSIKAEDCTVCWDTATVRWLSSS---LSA
ESFIVEYCRQHSPEG-EGLRSFAGIKKPELKVSLEPNVNYFFYLRAVNPFGTSEQSEAAL
ISTK--GTRFHLLSDTAHPALQISSNATVIHLPEKTKLSGFPSVLGELLPAQGCHYWEIV
VSACRSYRIGICYEAITQ-SSVLGLSDTSWCMRCCPTQT----RFLHTGVMSD---VHVT
EHLARIGILLDYNSGRLLFFNAERGLVLFAIRHKFTDAAHPAFALEKAGMLTLCTGMELP
DFVKQS

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------------------------------------------------MASSDSN-----
--HATESFLGS-------DGDEEATRGLETE-ESE----GEEDET----AAESEEEPDA-
-RLSDQDEEGKTKQECIISDPSFSMVTVQREDSGITWETNSNRSSTPWASEESQTSGVCS
PEGSTV-NSPPGNVSFIVDEVKKARKRTHK--AKRGSPS--LRRKANKKRNSFESQ-DVP
ANKKDNPLISESQEVNIEKEKSYT---GIYDKTRK----KKPTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
GNYDSNAVSKTGKS-----VAQSIEDE----------------KVKELAPPWRSTLFTG-
----------SKSLT---------SLFSHEDQ-KKTDVDSFLNTT--SASE---------
-----------------CTVSSYSSNDTEE---QETQLRPPQLV----------PQQPDN
EAKTHEMEPSPLSPD-TSATVF--LETAKEEFELASHADITPENDFSVSPSLVDEIKKED
VYSPDRSIS------LEA-------ESPGLAASTQEG----FGPDNEQLDLTS-------
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---------------------------------------LERTEPVSE------------
--QLTPP-----------HPNV-------------KGEKEENVLEPSMSLSESLLLEEPE
KVEVETSLPIAATPEPEDSNLTE-EEIIELESPESPLVSEKPFLPRL-SPEVEH------
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---------------KEEEPVLPLLT-S-------------TSERGTLSEEERE----EN
ESVSTDSAFVSEYSVL----------QDLNHELEE----REV------------------
----------------EPVSPSSVKTVAEHVVSS---------------EEENEEFEPPC
PAVASASEH--------------------------------------SLSPSTTEKTLEC
QSPPFSTVIPEHVVLSGDERSDS-----GRYMPESTSAS--------------EYSVPSH
AAKELL--KETIDYKTPLKS--KGVSEHMILSEE-KEDTGSYSP---AVASESEHSVSPS
TTEKPLECQAPLFST-VTPEHVVLSGDES-SESGRYTPESTSASEYSVPSPAAKESLKET
IDYKTPLKPKGVSEHMILSKEE--------------------------------------
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-------------------------------------------------------KKDIG
PYA--V-TSASEHS-FLP--------HTTEITSECQAPPL-----SATPSEHA-LLEEET
V-----EMERCTPTST---------SAS-EFSVPPYATPESQDEEIVHNFPLNLK-----
------------------------------------------------------------
----GALSPMNLSEED--QEDIGPFSPDSAFVSEFSFPSYATQEAEKREFECDSPICLTS
PSEHAILSDEDTEETELFSPDSAS--QVSVSPFRVPETEKNETELDSSLTEVSASEYSCF
SETDEEQI-GSTAA---TPV-PEHFS--SSQKQKAELFPLMSA--LEDLSLPPSGN--KS
EKAENEPDVQTTSTSVSEYLILTHK-------QKIQASL-EPESEDLISPYLK-------
--------S---ESEKVETKTS-PSVAATPA--SLLAQSSMAKEETKPVLPASQYSVSPD
SI-------------------HAIKKEQEPKSSLTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHAS------QD---QKMKPQPPN--
--VPGSGMEYSVMPEL-VD-----------------------------------------
-------------------EPKKDVKPNLAPNVTS--EQEQRILSKNEP---EVIVPFSP
LKKTSLSEP----------------------------EVLS----------VVETEVKHD
SEIMTPP----RVLHSASSGVAKEVE---------------------------------H
GPPA--------PAFSALS--EEVNRETEPSSSTTTTS-ITK---------LDS------
------------------------------------------------------------
---------------------------------------SLSKLVKEEIPTDS-------
-----------------------------------SLATPVDR-PVLTKVGK-------G
ELGSGLL----------------PL--VTSEDDHSVL-KEEEKVE---------------
---IK-DTSLVETSPFKLLAW--SEAE-----KEVK-------LDSPLSVSSVSEHSIFS
KVETEEVKPELPITKASFSQ------------------HSDVSEEAKVE------DKQGL
SFSTVSDSECLVLSQKKNLVSASEASGPERVLSFNLSGEIKKEETKFPLSQNVSPAPKHI
LPKSKDEEIASSSDFENLV-SGDLAPALLTLSDHKNKQAMEASPIAQGDFLPEKRDLGLV
E-----LSLEPEKKDELHQLSELPK---AESEFTNGLGRQSGSIGIKQVKSPIIETGDSV
LEKDLAELRSRE-GKEENRELHV--PTTV-PAISEISVCLGEETQNEEIKLFSPKVVSLR
SKEAPTSLIEGDNPEELQPSNFSLKGLSEELNHSTDFKKGESQEIGPLLPTRNLKTQVME
DIGTKLNEETGHPN--SACVFQSITQPSKISSSDLLEE-WKTEK----ALHSDQAIKLPD
IS-----TSFADKQDLGIKQVLFMKENLPLEQSKSFMTTKPADVKETKMKESFISPKD-E
NWMLEKPENL-ASQHEERILGTMESDSSGS--NDLMTGQPKAAV----------------
-LDKDHAYEIRKQVLPHSAEELHLPLQEPGSTLDTSSGTVETLLSKTYSFEEVKL-AQEP
TSLVLAGQVERNIAEEKQIHSFVGSECVRLEKSNTEFSRPCKE-ESQKEIKLPPERILQ-
KPVSGPSVEQVKSETIPSPVKTAHFLEEIVEPSL-GN---EEAAH-WSTSPLPGEKPLEE
SKMVPSKVVDDNGE-----GGKPAPEV-KMPTQREP-LSSILT-GQEAHPPESAEETQKL
PEQPKVV-KPDLPEEKRKKGISSFRSWMSSLFFGSSTPDNKIAEK-EDL-ETQPSSPVEK
AVTVI-EPKGTI---P-TDFNATKKAADPSLPGVKLKTADESRGTLDKSGEGQDFK-AQS
TLLSKVEVSQRLKSD---SEVSSEDYGKKEIPDYSEEMSIKSIVTSADGEEHLGTQPFSP
AGENLVVEEAKNVAPLNATESKRVQKP------------AIAPPSTWNISILQAEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPESASSVFTSKNI------------MKESEKPESIILPVKESKGSLID
LGEDRLKKEMLKPISLKISEEEIKLRSVSPSEEKDNLETRSDILAEKKVLEEKQDTV-AP
SELRDNNEVGKAQITLGSRPTELEESKAAAMLQQVCQN-EDHRERSKITVSSE----EEK
GE---EKEKQAHVFSEEEKKQEHQPYSVNVSRFMAKELDV------------------S-
--LGHSLG-E-----TQPFSLVKATSIIEKSET---------------------------
-----NLSKAHSEIRETKAVGTQPYPLEENKVSVEKTKTFLP--------VDLSCRDEID
NHSLSQEGNLALEK--S-------------------------------------------
---------------------------------------------HKDMLGPSEEKGQ-F
KVSELSKGGLIDTTKESMKQG----------TPSKESERSLDHRFDETNNLETPPYLLSS
VKP-----QTIGSGASPEINTTKKQEIPWSEL-----------TPD--------------
---------RHTVHTIQTSKDHTS-----DMPKQSVIVSK----RHLEAGKDTHVSEPLS
SARSNYA-EFI-----TNASAIHADKMVSTKEMSKEPEDTYTKDEEF-------TVTSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFIFSADQEESEQMQDKLEYLEEKASFKTLS
-PHDYREAVACHKIVK-SKL---EDSDEKVVSLKE-NKEEETH---------KTK-EIAT
DSETGHLAFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
PKEIISFPESLEEHALEREYDLV-KLDERFYGPEKDHSKE-SYPETQKSFVIQKSAD--R
NAS-KGINRDVDSKSPGMPLFEAEEGILSRTPIFPTTAKAINPELLEEPPALAFLYKDLY
EEAVGDKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTQKD
QGQGLEE-RVGKDDSYQPIAA--EGEIW---GRFGTTLGEKSLEDEQ-KAVHREGESVGH
METLGNVA-TQKKVPITEEVRVVTQK-ISYAVPFEDTHHVLEPIDEA-------------
-------SSQG------NQ------AG---------NASPEVNLNVPVQVSFPEE-EFAS
GATYVQETPQEEPKIVVPLEPSEE--RLRNSPVQDEYEFAESANYEVVTQ-DILPEE-LY
SESTPEDVS-SQRKESFEHTS--ENEFMSEAEQSPSAEQRELGRGRKEHDHLPSE-LVTE
KAQMELKKSQIDTYCYTCKSPISATDKAFGTHEDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFKTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLENMPAAFSLFEHYDDGSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCLEEPQDDQEV--NELVEEYRVTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSNGTVISFTERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAVQ-AGTLGQGDTSWYMHCSEPQR---YTFFYSGITSD---VHVT
ERPARVGILLDYNHQRLLFINAESGQLLFIIRHRFNESVHPAFALEKPGKCTLHLGIEPP
DSARHK

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--------EQKDLFNIISEGYEILNIHAPTHISSVDQEESKHMPDKLEYLETNPSFKRK-
LAHDSCSALASGTTTE--------ISDRSVLGKPETHEQKELVK----------------
N-ESNTDVILDPDN----GMADMDYFEKYTLIDDKSPVKPHFERL-SSSF-PETEDPNEP
VEQAASFKESTEADTLEEEFSLLEDLDEVFYGTAKGESKMQAYAAAPESLPPQKSID--I
SSK-RVTNIEDERKSPGTPLFDSEEGVLERSLFFPTSVAAVNPELLEEPPALSFLYKDLY
AEAVGEK-TKGETPSDEESGNSNASFPSRNSDTDDGTGIYFEKYILKDEIPGKVLDHQED
QIPEDESFSGGIS--VQSY----EDKYK---YSSTGVLG----TEI---LPER-GVV---
---------ETEKVQVDSDIKA-TICKPMHAIPFGREAVLS----GA-------------
-------RSDT------TEGAAHPEAGNKREEQHKVTAVPQI---------TPVE--DSE
DDQYTQENISCVPTVQQREKTDLQ--REEQQHPDAYEDLAESMDYDVITQEELLQDE-IS
SEFTHEELL-FEDRDSFEHVG-DSYEFVNEPEQRTPVELEDSGFVVMYPEKSMANIPQVE
SPQRELKKAQTDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDQLGELLKALEE
KSMKIEEFVSDIESLFNSVEENCKKNAELLEKQNEEMLKKVVAQYDEKSENFEEVKKMKM
EYLYEQMVNYQQTVDSAKETLETTVKEMEELDG--FVFLNS-----------SK-ELNKR
LLSAMDTTLSLEKVPSAFSLFEHYADSPGKSNQHSLKQVAVPQTPSVIPQEQNSATSTS-
-IAVYWTVNEGDAIDCFQVYCMEEPQASKDEAGAALVEEYRVTVKESHCILEDLEPDRTY
SVWVMA----VNCTGCSLP SEKAIFKT APAIPTIKAEDCMVCWDTATIRWHDGS---AAA
ESFTLEYCRQHSPEG-EGLRSFSGIKRNELKVSLEPNVNYFFYLRAVNTFGTSEQ SEAAL
ISTK--ATRFHILSGTAHPALQISPDATVICLPEKAKFTGFPSVLGELLPA RGRHYWETV
VSACRSYRIGICFETTPQ-SSALGLSDNSWCMHCCPTQTSFLYRFFHTGVMSD---VHVT
EQPARIGILLDYSGGRLLFFNAERGLVLFAIRHKFTDAAHPAFALEKAGVLTLHTGMELP
EFVKHS

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----------------IFESDEVVNIHALTDK-----EE-PHVLKSLQHSEKVYSLKTK-
QLNNSEDTAVDHEPSISGKALKAGKHENRENGSKEHVEQKHVK------------ES---
TEAEGDISVLPESRGDILKNIDMEYV--DNLIDDTSFSQTGKEKSIQEAQ-RPSDVTKKT
LEEARSLVESSEKTL-NLSL-LERNLDEVSCGIDKKGNIMATHESTLKLLDENKEIDVVT
ETD-KNIEGGLDLAESGVPLFNSEKDISSQSPLTSLPVSAGSP----EPPALAFLYRDLH
EEVMGASEEDSECSASEEIMSTAVPIPATTHAPYDGTEIFLKKDIPEDYIPNNLEESQKE
E--VLKDQPINEPAVNQSSILENAHEINKEQNEFVHILTEPY---DQ-TAVVAPREM---
VENMVDKL-TKGPAEIVSNINVGICH-PTHAIPFGSASNDDE------------------
-------DSQK------EESIPEERGEMLPEETSDEESSPIL--------------DYAA
TVYQNEATVQHEPKDTCFAVGQNQQPIERPIQWTDNEDLAELMDYEMVTQDDVFQEE-TS
SEVACEELL-FDDKKTLDHIS-NTYEFVNEGEISTYAEEDEF--ELMDPERLPRNVPEIE
VLQKEIDEAQFDTYCYQCKCPISADDKLSGEHKEHDMTNLDTAMTVLKGQLDRYLDVLQE
RSLKIEGFVSEIEALFNSLEENCKEKEQHLEEQNENIIKTVVGHHDRTAQNFEGVKKTKM
EYLYEKMVNFQEYIDTAKETLEAIIKEAEEMDD--FTFLT----SSE--------EINKR
LLSAVEDILTLEKMPSEFSQFKNYACGTANGDQ-TLKHIPVPQTPKLQPQDPNSATSTS-
-ITVYWTVNEEDVIDFFQVYCMEEYPGSKEQ--SGLVEEYRVIVKESNCILEDLEPGHSY
SVWVMA----VNYTGCSFPSDKSTFRTAPRIPVIKAEECTVCWNTATIRWSSSN--PETT
DSFTLEYCRQYSPEG-EGLRSLAGIKRPEVKVHLESNVNYFFYVRAVNVFGTSDQSEAAL
ISTK--GTRFHIMKETAHPALQVSPNGTMICFPEDTELPNCSPVLGELLPAQGWHYWETT
VNGCAAFKVGICYSSPSH-DSIMGQNNVSWCLHHSSKE-SFVYKVLHNGEMSN---VIVT
EQPDRIGILLDYNAGRLLFFNAERGQVLSAIRHKFNHPAHPAFVLEQPGVLNLHTGMELP
EFVKQS

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------DGDEEATRELETEEESE----GEEDET----AAESEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSR-STPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKGSPLTSASQILTTEKEKSYT---GVYDKARK----KKTPSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKG-
----------SESLT---------SMFSHEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPG-TPATVF--LRTAKEECELASPGTAASENDSSVSPSFTNEVKKED
VCSAHHSIS------LEA-------ALPDLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERADPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIDTSLPVAATPKPEDSNLVE-EEIIELDYPESPLVSEKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPENAALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----RES------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSPLFSTVTPEHMVLSGDEASES-----GRYTPDSTSAS--------------EYSVPSQ
ATKESL--KKVIDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTP---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSECFTPDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKGISEHTVLSVEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
PSSPDS-VIASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEET
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFASEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKSETFPLISP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPPHLT-------
--------S---EVKKGEREAS-SSVTAIPA--SLPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--IPGFEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSEKEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSALS--EEIKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVGH-PVLTKVGK-------G
ELGSGLL----------------PL--VTSTDEHSVL-AEEDKVA---------------
---IK-GASPNETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------YSDESEEARVE------DKQGL
SCSTVRDSEHLVSSEKKSLVSTSEVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENS-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDIALA
E-----LSLEPEKKNKPHQLLELPN---AGSEFASGLGRQSGSIGTKQAKSPVTETGDSV
LEKGPAELRSRE-GKEENRELYA--SATM-PTTSELSSLLREESQNEEIKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLVE--QKTEK----ALHSDQTIKLPD
VS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEELKL-AEEP
KSFVLAGNVERNIAEEKESHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVKTTHFLAEGVEPAL-GN---EKEAH-RSTPPFSGEKPLEE
SKMVQLKVIDDADE-----EKKPAPEV-KIPTQRKP-ISSLHS--KEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKGKKGISSFKSWMSSLFFGSSTPDRKVAEQ-EDL-ETLPSPSVEK
AVTVI-EPEGTI---P-TNFNVAEKQADHSLSEVKLKTADESRGTLVKSGEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEVNINSVVTSADGEKHLEIQPYSL
IGEKLIMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKSESIILPVEESKGSLVD
LSEDRLKKEMQNPTSLKISEEETKLRSVSPTETKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNEIGKTQITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEEKKKQEHQPYSVNVAESMIKESNI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSDA---------------------------
-----VLSDAHPEIREAKAVATQPHPLEESKVLVEKTKTFLP--------VALPCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMPDHSEEKEQ-F
RESELLKGGSVDITKESMKQG----------FPTKESERTLAYPFDETKSSETPPYLLSS
VKP-----QTLVSGASPEINAMKKQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTF-----DVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTV-
PLRDDSETVACHKTLK-SRL---EDSDEKVTSLKE-SKQKETR---------HTEEKTST
DSE-TDLSFIQSTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEDKLSEEV
TEEATSFPGSSVESALEHEYDLV-KLDESFYGPEKDHDIL-SHPETQKSLGIQKSAD--R
NVS-KDVKRDVDSKSLGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKNKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVGH
VETLGDIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPDVNLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILVPPEPSEE--RLRNSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAEQKELGSEWKEENQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MVTVQREDSGITWETNSSRSSTPWTSEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNKKRNSLESQ-DVP
TNKKGSPLTSASQILTTEKEKSYT---GVYDKARK----KKTPSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKG-
----------SESLT---------SMFSHEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPG-TPATVF--LRTAKEECELTSPGTAASENDSSVSPSFTNEVKKED
VCSAHHSIS------LEA-------VLPDLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIDTSLPVAATPEPEDSNLVE-EEIIELDYPESPLVSEKPFPPHM-SPEVED------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----RES------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSPLFSTVTPEHMVLSGDEASES-----GRYTPDSTSAS--------------EYSVPSQ
ATKESL--KKVTDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTP---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHVVLSEGED-LGSECFTPDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKGISEHTVLSVEG-KEDI-GPASPDS-------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VIASEHTVLSVE-GKEDIG
PSSPDL-VVASEHS-FPP--------HTTEVTSECQAPPL-----SATPSEYVVLSDEET
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFASEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKSETFPLISP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSTSVSEYLILAQK-------QKTQAYL-EPESDDLIPPHLT-------
--------S---EVKKGEREAS-SSVTAIPA--SLPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQKPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATVHVS------QD---QKMEPQPPN--
--VPGSEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGIKPKLVLNVTS--ELEQRKLSENEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSALS--EEIKKEMEPSSSTTTAF-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVGH-PVLTKVGK-------G
ELGSGLP----------------PL--VTSTDEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVSS
EVEAKEVKAGLPVIKTSSSQ------------------YSDESEEARVE------DKQGL
SCSTVRDSERLVSSQKKSLVSTSEVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENS-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDVALA
E-----LSLEPEKKDKPHQPLELTN---AGSEFARGLGRQSGSIGTKQAKSPITETGDSV
LEKGPAELRSRE-GKEENRELYA--SATM-PTTSELSSLLREESQNEEIKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEGSHPADFKKGGNQEIDPLPPTGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLLVEQKKTEK----ALHSDQTVKLPD
VS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKSADVKETKMEAFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEELKL-AEEP
KSLVLAGNVERNIAEEKESHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVKTAHFLAEGVEPAL-GN---EK-AH-RSTPPFSGEKPLEE
SKMVPLKVIDDADE-----EKKPAPEV-KISTQRKP-ISSLHA--KEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKGKRGISSFKSWMSSLFFGSSTPDSKVAEQ-EDL-ETLPSPSVEK
AVTVI-EPEGTI---P-TNFNVAEKQADHSLSEVKLKTADESRGTLVKSGEGQNIK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEMNINSVVTSADGEKHLEIQPYSL
IGEKLIMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKPESIILPVEESKGSLVD
LSEDRLKKEMQNPTSLKISEEETKLRSVSPTEKKDNLENRSSTLAEKKVLAEKQDSV-AP
LELRDSNEIEKTRITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----EEK
GE---EKENQVYVLLEEKKKQEHQPYSVNVAESMIKESDI------------------S-
--LGHSLG-E-----TQSFSLVKANSVTEKSEA---------------------------
-----MLSEAHPEIREAKAVATQPHPLEESKVLVEKTKTFLP--------VALPCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------SNRDMPDHSEEKEQ-F
RESELSKGGSVDITKESKKQG----------FPTKESKRTLAYPFDETKSSETPPYLLSS
VKP-----QTLVSGASPEINTMKKQEMPQSEL-----------TPE--------------
---------RPTVDTIQTSKDDTF-----DVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTV-
PLRDDSETVACHKTLK-SRL---EDSDEKVTSLKE-SKQKETR---------HTEEKTST
DSETGDLSFIQSTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEDKLSEEV
TEEAISFPVSSVESALEHESDLV-KLDESFYGPEKDHDML-SHLDTQKSLGLQKSAD--R
NVS-KGVRRDADSKSPGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKSGTICREKSLE-EQ-KGVYGEGESVGH
VETLGNIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPEVNLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILVPPEPSEE--RLRSSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAEQKELGSERKEENQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDGSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVVDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLVRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DAVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MVTVQREDSGITWETNSNRSSTPWASEESQTSGVCS
LEGSTV-NSPPGNVSFVVDEVKKARKRTHK--AKRGSPS--LRRKANKKRNSLESQ-DVP
ANKKDNPLISES----IEKEKSYT---GIYDKTRK----KKTASNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
GNYDSNTVSKTGKS-----VARSIEDE----------------KVKELAPPWRSTLFKG-
----------SKSLT---------SLFSHEDQ-NKTDVDSSLNAT--SASE---------
-----------------HTVSSYSSNDTEE---QETQPRPPQSV----------PQQPDN
EAKTHEMEPSPLSPD-TSATVF--PETEKEEFELASHTAVTPENDSSVSPSLADEVQKED
MYSADRSIS------LEAEKDFLERGSPGLAASTQEA----FGPDNEQLDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSE------------
--QLTPP-----------HPNV-------------KGEKDENVLEPSMSLSESLVLEEPE
KEDIETSLPIAATPEPEDSNITE-EEIIELEYPESPLVSEKPFLPRL-SPEVEH------
------------------------------------------------------------
---------------KEEEPVLPLPTTS-------------TPARGTLSEEERE----EN
ESVSTDSAFVSEYSVP----------QDLNYELEE----REV------------------
----------------EPVSPSSVKTIAEDIVLS---------------EEENEKCEPRS
PAVASASEH--------------------------------------SLWPSTTEKPLEH
QSPLFSTVTPEHVVLSGDEDSES-----GRYTPESTSTS--------------EYTVTSH
AAKELL--KETIDHKTPLKS--KGVSEHMILSEK-KEDTGSYSP---AVASESERSVSPS
TAEETLESQSPLFST-VTPEHVVLSGDES-SESGRYTPESTSASEYSVPSHAAKELLKET
IDHKTPLKSKGVSEHMVLSEEE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KKDIG
PYSPAV-ASASEHS-FPP--------HTTEITSECQAPPL-----STTPSEHV-LSEEEI
V-----EMERCTPSST---------SAS-EFSVPPFATPESQEEEIVHNFPLNVK-----
------------------------------------------------------------
----GALSPMNLSEED--QEDIGPFSPDSAFVSEFSFPSYETQETEKREFERDSPICLTS
PSEHTILSDEDTEETGLFSPDSAS--QVSIPPFKVPETEKNETELDSLLTEASASEYSCF
SETDEEQI-GSTAA---TPV-PEHFS--SSQKQNAEPFPLISA--LEDLSLPPSGN--KP
EKAENEPDVQTTSTSVSEYLILTHK-------QKTQASL-EPQSEDLIPPYLN-------
--------S---ESEKGETKTS-PSVAATSA--SLLAQSSMAKEETKPVLPASQYSVSPD
SL-------------------HAIKKEQEPKSSLTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHAS------QD---QKMKPQPPN--
--VPGSGMEYSVLPEL-VD-----------------------------------------
-------------------EPKKDVKPNLAPNVTS--KQEQRILSKNEP---EVIKPYSP
LKETSLSAP----------------------------EVLS----------VVKTEVKHD
SKIMTTP----RVLHSASSGVAEEVE---------------------------------H
GPPA--------PAFSALS--EEVNRETEPSPSTTTTS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTQLVKERIPTDS-------
-----------------------------------SLATPLDR-PVLTKVGK-------G
ELGSGLL----------------PL--KTSTDEHSVL-KEGEKVE---------------
---IK-DTSPIEISSSKPLAW--SEAE-----KEVK-------LDSPLSVSSISEHSILS
KVETEEVKPALPITKAS-SQ------------------HSDVSEQAKVE------DKPSL
PFSIVLDSEYLILSQKNNLLSASEVSGPEHVLSLNLSGEIKKEETKLRLSQNVSPAPKDI
LPKSKDEEIASSSDFENLV-SGDLAPTLLTLSDDKNKQAMEASPTAQGDFLSDKRDIALT
K-----LSLEPEKKDELHQPSELPK---AESEFTNGLGRQSGSIGTKQVKSPIIETGDSV
LEKDLAELRSRE-GKEENRKLHV--PTTV-PAISEISSCLEEEPQNEEIKPFSPKVVSLG
SKETPTSLVERDNPEELQPYNCSLKEVSEELNYSTDFKKGESQEIGPLPPTRKVKTQVMQ
DIVTKLNEETSHPN--SACIFQSITEPSKITSSDLLEE-QKTEK----GLHSDQAVKLPD
IS-----TSFVDKQDLGIKQVLFMKENVPLEQSKPFMTTKTVDVKETKMKESFITLKD-E
NWMLEKPENL-ASQHEERILGTMESDSSRD--DDLMTGQLKAAV----------------
-MDKDHDYEIRKHPLPHSAEEPHLPLQGPGHALDTSGGNVEPLLSKTSSFEEAKM-AQEP
TSLVLAGKVEKNIEEEKQIHSFMGNESMILEKSNTEFSRPCKE-ESQEEIKLPPERILQ-
KPVSGPSVEQVKSETMPSPVKTAHFLAEIVEPSL-GN---EEAAH-WSTSPLPGEKPLEE
SKMVPSKVVDDASE-----GGKPAAEV-KMPTQREP-LPSILA-GQEAHPPESPEETQKL
PEQPKVV-KPALLEEKGKKGISSFRSWMSSLFFGSSTPDNKTAER-EDL-ETQPSSPVEK
AVTVI-EPKGTI---P-TDFNATEKPADPSLPGLKLKTTDESRGTLVKSSESQDFK-AQP
TLLSNVEVLQQPKSD---SEVSSEDYGKKEIPDYSQKMNIKSIVTSADGEEHLGAQPFSP
AGENLVVEEAKNVAPLKATESKKVQKP------------AIAPPSTWNISILQEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPEPASSVFTSKNI------------TKESEKPESIILPVKESKGSLID
LGEDRLKKEMPKPISSKISEEEIKLRSVSPGEEKDNLETRLNILAEKKVLEEKQDTV-SP
LERRDNNEVGKAQIT----PTELEESKAAAMLQQVCQN-EDHRERSKIIVSSE----EEK
GE---EKQKQARVFSEEEKKQEHQPYSVNVSRSMPKELDV------------------S-
--LDHSLG-E-----TQPFSLA--TLVIEKSET---------------------------
-----NLSKAHPEIRETKTVATQPYPLGENKVLVEKTKTFLP--------ADLSCHDEID
NRSLSQEGNLVLEK--S-------------------------------------------
---------------------------------------------HRDMLGSSEERGQ-F
KASELSKGGLIDITKQSVKQG----------SPSKESERSLDRPFDETKNLETPPYLLSS
VKP-----QTIASGASPGINTAKKQEIPWSEP-----------TPD--------------
---------RHTVHTIQTSKDHTS-----DMPKQSVPVSK----QHLEAGKDTHVNEPLS
SARSNYA-EFI-----TNASAIHADKMVSTQEMSKEPEETYTKDEEF-------TVTSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFIFSADQEESEQMQDKLEYLEEKASFKTLS
-LHDDREAVACHKILK-SKL---EDSDEKVVSLKE-NKEEETH---------KTKEEIAT
DSQTGNLAFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLS-GEEKLSKEV
IKETISFPESLEEHTLEHEYDLV-KLDESFYGPEKDHSKE-SYPETQKSLVIQKSAD--R
NVS-KGINRDVDSKSPGMPLFGAEEGVLSQTQIFPTTAKAINPELLEEPPALAFLYKDLY
EEAVGEKKKVGETASEGDSVNSEASFPSRHSDTEDGAGIYFEKYILKDDILHDTSVTQKD
QGQGLEE-RVGKDDSYQPIAA--EGEIW---KRLGTTLGEKSLEDEQ-QAMYSEGESVGH
VETPSNVA-MQRKVPITEEVRVVTQK-ISYAVPFEDTHHVLEPIDEA-------------
-------SSQG------NQ------AG---------NASPEVNLNVPVQVSFPEE-EFAS
GATYVQETPQEEPKILVPLEPSEE--RLRNSPVQDEYEFAESPNYGVVTQ-DILPEE-LY
SESTPEDVS-SQRKESFGHIS--ENEFVSEAEQSLSAEQRELGRERKERDHLPSE-LVTE
KAQTELKKSQIDTYCYTCKSPISATDKAFGTHKDHEISTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTVEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLENMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRVTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATVRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSNGTVISFTERRKLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAVQ-AGTLGQGDTSWYMHCSEPQR---YTFFYSGITSD---VQVT
ERPARVGILLDYNHQRLLFINAESGQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASSESN-----
--HTGESFLGS-------EGDEEATRELETEEETE----GEEDET----AAESEEEPDA-
-RLSDRDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKARKRTPK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKDSPLTSASQVLAPEKEK--S---GIYDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTRKL-----VAQSIED-----------------KVKEVAPPWRGILSKG-
----------SESLP---------SMFSHKDQ-KKIYADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QELQLRPSQSV----------PQQPED
EAKPSEVEPP------SATTAF--LRTAKEEFEVASQGTAASASDSSVSPSFANEVKKEG
VYSAHHSIS------LEA-------ESPDLAASTQEG----LDPDQEHPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------QRAEPVSA------------
--KLTPA-----------QPSV-------------KGQKEENVLEPSISLSEPIMLEEPE
EEEMETSLPIAATPEPEDSNLVE-EELIELDYPESPLVSEKPFPPRA-SPEVAH------
------------------------------------------------------------
---------------KEEELILPLLT-S-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----REG------------------
----------------EAVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASVSDS--------------------------------------SLSPFTT-KTSEI
QSPLFSTVTPEHVVLSGDEASES-----GHYTLDSTSAS--------------EYSAPSQ
ATKESV--KKIIDHKPPLIS--KDVSEHLIPSEE-KEDTGSFTP---AAASASESALSPS
ATEKTSECQSPLPST-ATSEHVVPSERED-LGSERFTPDSKLASRYAAPLNATQEAQKKI
IDEASQFKPKGISESTILSEEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIE
PSSPDS-VAASEHS-FTP--------HTTEMTSEHQAPPL-----SATPSERGVLSDEET
V-----ELERYTPSST---------SAS-EFSIPPYATPESQEEEMVHR-SLNLK-----
------------------------------------------------------------
----GASSPVNSSEED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTVFSDEDTEEAELFSPDSAS--QVSIPPFRIPETEKNDLEPDSLLTAASASGYSCF
PGADEEDI-GSTAA---TPV-PELYS--SSQKQKAETFPSTSP--LEDLSLPPSTD--KS
EKAETKPEIPATSASVSEYLILAQK-------QKTQASL-EPKSEDLIPSHLT-------
--------S---EVEKGERKAS-SSVAAIPA--SLLVQSSVVKEETKPASP---YSVSPD
SV-------------------PAIKKEQEPTAPLTLK---------AVDEQM--------
-ALPKVR---------------KEEIVPDSQEAIGHVS------QD---QKMEPQPPN--
--VPESETKYSILPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQGKLSKNEP---EVIKPYSP
LKETSSSGP----------------------------EVLP----------AVKMEMKHD
SKITSTP----SVLDSASSGVHKQVE---------------------------------H
GLPE--------LAFSALS--EEINKELEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKLGKEEIPTDS-------
-----------------------------------SLVTPVDR-PVLTEVGK-------G
ELESGLL----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------CDSPPSVSSIAEHSVLS
EAEAKGVKAGLPIIKTSSPQ------------------HSDESEEARVE------DSQGL
SYSTVRDSEHLVSSQKKNLVSTSEVLGPEHELSLSLEGEIKKEETKLPSSQNVSIAPKHI
VPKGRDEEIARSPPELENL-ASGLAPAVLLLSDDKNKHAVEVSSSAQGDFPSEKQDIALA
Q-----LSLEPETKDKPHQLAELPN---AGSEIASGLGRRSGSIDTKQAKSPITETEDSV
LEKGLAKLRSRE-GKEDSREFYA--SATV-PVISELSSFFREESQNEEIKSFSPKIVSLE
SKETPASLAEGDNPEEFQQFSFPLKGLSEELSHSADFKKGENQEIGPLPSPGNLRAQVMG
DTVTRLNEETGHPD--SSQVLQSITEPSKIAPSDLLAEQKKTEK----ALHSDQTIKLPD
GS-----TSFAGKQDLDIKQFSSMEENLPLEKS---ITAKPMDVKET-REEFFISPKD-E
NWMLGMSEHV-ARQHEERRAGSVQLDSSGS--NELRPEHLQAAV----------------
-SSKDHTCEVRKQVLPHSAEESHLSSQEPVSALDTSSGNVETLSSQSYSSEEVKL-AEEP
KSLVLAGNVERNVPEKKERHSFMESERLLLEKANTEFSCPSKE-DSQEKIKLPPERFLQ-
KSVSGPSVEQVKSETIPSSVKTAHFLAEGVEPAL-GN---EKESH-RSTPPFPGEKPLEE
SKMVQSKVIDDADE-----GKKPEPEV-KIPTQRKP-ISSIDA--KEPQPLESPEVTQKP
PMQPKVA-KPDLPEEKGKKGLSSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPSPSVEK
AVTVI-EPEGTI---P-ANFNVAEKPADHSLPEVKFKTADESRGTLVKFEEGQNVK-EKS
TILSNLEELQQPKSI---SEVFREDYGKKEISGDSEEMSINSVVISADGEKHLGIQPYSL
IGEKLVMEEAKTVVPLHVTHSKGVQKP------------AISPPSNWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKLASSNFASKNI------------TKESEKPESIILPVEESKGSLID
LSEDRLKKEMQKPISLNISEEETKLRSISPTEKKDNLENRSYTLAEKKVMAEKQDSV-VP
LELRDSNEIGKTQVMHGSRSTEQEESKVNAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEGKKQQKHQPYSVNLAESVTEKSDI------------------S-
--LGHSLS-E-----TQSFSLVKAASVTEKSEA---------------------------
-----MLSEAHSEIRETKALGTQPHPLEESKVLVEKTKTFLP--------VDLSCHDEIK
NHSLSQGGSLVLE-----------------------------------------------
-------------------------------------------KSSRDMPGHNEEKEQ-F
KESELLKGGSLDITKESMKQG----------FPSKESERTLAHPFDETRSSETPPYLLSS
VKP-----QTLASRASPEINAVKKQEMSRSEL-----------APE--------------
---------RHTVHTIQTSKDHTS-----DVPKQSVLVSK----HQLEAVEDTGVKEPLS
SAKSNYA-QFI-----SNASASNADKMVSTKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKLSFKTI-
PLPGNSEAVACHETLK-SRL---EDSDERVTPLKE-NKQKETH---------KTKEEIYT
DSETGDLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
TEEMISFPVSSVESALEHEYDLV-KLDESFYGPEKDHDVL-SHLETQKFLGIQQSAD--R
NVS-KDIKRDVDSKSLGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEEETVSEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTQKD
RDQGLEEKRVVKDDSYQPIAA--EGEIW---GKFGTIHEDKSLE-EQ-KAVCGEGESVGH
VEILGNIA-MQKKSPITEEVRVATQK-ISYAVPFEDSRHVLEHTDEA-------------
-------GSQG------NE------VG---------NANPEVNLNVPVQVSFLEE-EFAS
GATHVQETLLEELKVLVPPEPSDE--RLRNSPVQDEYEFAESLHYEVVPQ-GILSEE-LS
SESTPEDVL-SQGKESFEHIS--ENEFVSEAEQSTSAGQKELGSERKEQDRLSSE-FVTE
EAQKEPKRSQIDTYCYTCKSPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKHATVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFFGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPAT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
IST------------------------------------RIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGTLGQGETSWYMHCSEPQR---YTFFYSGIMSD---VHVT
ERPARVGILLDYNNQRLVFINAESGQLLFVIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSLRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASSESN-----
--HTGESFLGS-------DGDEEATRELETEEETE----GEEDET----AAESEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKARKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKESPLTSASQVLTTVKEK--S---GIYDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTRKL-----VAQSIED-----------------KVKEVAPPWRGTLSKG-
----------LEFLP---------SMFSHKGQ-KKIYADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QELQLRPSQSV----------PQQPEE
ETKPREVEPP------SPATAF--LRTAKEECEVASQGTAASASDSSVSPSFANEVKKED
VYSAHHAIS------LEA-------ESPGLAASTQEG----LDPDQEHLDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------QRAEPVFA------------
--KLTPA-----------QPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
EEEIETSLPIAATPEPEGSNLVE-EEIIELDYPESPLVSEKLFPPRA-SPEVEH------
------------------------------------------------------------
---------------KEEELILPLLT-S-------------APEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----REG------------------
----------------EAVSPSNIGAIAEHAVLS---------------EEENEEFEAYS
PAAASASES--------------------------------------SLSPFTT-KTSES
QSPLFSTVTPEHMVLSGDEASES-----GCYTPDSTSAS--------------EYSAPSQ
ATIESL--KKIIDLKSPLIS--KDVSEHMIPSEE-KEDTGSFTP---AAASASEPSLSPS
TTEKTSECPSPLPST-ATSEHVVQSERED-LGSECFTPDSKLASKYAVPLNATQESQKKI
IDEASQFKPKGISERTILSEEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIE
PSSPDS-VAVSEHS-FPP--------HTTEMTSEHQAPPL-----SATPSECGVLSGEET
V-----ELERYTPSST---------SAS-EFSIPPYATPESQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPVNSSEED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTIFSDEDTEEAELFSPDSAS--QVSIPPFRIPETEKNNLEPDSLLA---ASGYSCF
PGADEEDI-GSTAA---TPV-PELFS--SSQKQKAETFPSMSP--LEDLSLPPSTA--KS
EKAETKPEIPATSASVSEYLILAQK-------QKTQTSL-EPESEDLIPSHLT-------
--------S---EVEKGEREAS-SSVAAIPA--SLLAQSSVVREETKPASP---HSVSPD
SV-------------------PAIKKEQEPTAALTLK---------AVDEQM--------
-ALPKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--VPGSETKYSILPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQGKLSKNEP---EVIKPYSP
LKETSLSGP----------------------------EVLP----------AVKMEMKHD
SKITSTP----SELDSASSGADKQVE---------------------------------H
GLPA--------LAFSALS--EEINKELEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKLGKEEIPTDS-------
-----------------------------------SLVTPVDR-PVLTKVGK-------G
ELESGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKGVKAGLPIIKTSSSQ------------------HSDESEEARVE------DKQGL
SYSTVRASERLVSSQKKNLVSTSEVLGPEHELSLSLEDEIKKEETKLPSSQNVSPAPKHI
VPKGRDEEIASSPPELENL-ALGLAPTVLLLSDDKNKHAVEVSSSAQGDFPSEKQDVALA
Q-----LSLEPEKKDKPHQPSELPN---AGSEFASDLGRQSGSIGTKQAKSPITETGDSV
LEKGLAKFRSRE-GKEENREFYA--SATV-PAISELSSLLREESQNEEIKSFSPKIVSLE
SKETPVSLAEGDNPEEFLPFSFSLKGLSEELSHSADVKKGENKEIGPLPSPGNLRAQVMG
DIVAKLSEETGHPD--SSQVLQSITEPSKIAPSDLLVEQKKTEK----ALHSDQTIKLPD
VS-----TSFAGKQDLDIKQFSFMKENLPLEQSKSFVTAKPMDVKETTREEFFISPKD-E
NWMLGKPDHV-ARQHEERRAGSVQLDSSGS--SELRPGQLQAAV----------------
-SSKDHTCEVRKQVLPDSAEESHLSSQEPVSALDTSSGNVETLSSQSYSSEEVKL-AEEP
RSLVLAGNVERNVPEKKESHSFMESESLLLEKANTEFSCPSKE-DSQEKIKLPPERFLQ-
KSVSGPSVEQVKSETIPSSVKTVHFLAEGLEPAL-GN---EKEAH-RSTAPFPGEKPLEE
SKMVQSKVIDDADE-----GKKPEPEM-KIPTQRKP-ISSIDA--KEPQPLESPEVTQKP
PTQPKVA-KSDLPEEKGKKGLSSFKSWMSSLFFGSSTPDNKVAEQ-DNL-ETQPSPSAEK
AVTVI-EPEGTI---P-ANFNVAEKPADLSLPEVKFKTADESRGTLVKFDEGQNVK-EKS
TILSNLEDLQQPKSI---SEVSREDHGKKEISGDSAEMSINSVVTSADGEKHLGIQPYSL
ISEKLVMEEAKTVVPLHVTHSKGVQKP------------AISPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKLASSNFASKNI------------TKESEKPESIILPVEESKGSLID
LSEDRLK-EMRKPTSLKIAEEETKLRSISPTEKKDNLENRSYTLAEKKVMAEKEDSV-VP
LELRDSNEIGKTQITRGSRSTEQEESKVSAMPQHFYQN-EDYRERPKIVVGSE----KEK
GE---EKENQVYVLSEGKKQQKHQPYSVNVAESMTEKSDI------------------S-
--LGHSLG-E-----TRSFSLVKATSVTEKSEA---------------------------
-----MLSEAHSEIRETKAVGTQPHPLEESKVLVEKTKTFLP--------VDLSCHDEIK
NHSLSQEGNLVLE-----------------------------------------------
-------------------------------------------KSSRDMPDHNEEKEQ-F
KESELLKGGSVDITKESMKQE----------FPSKEFERTLAYPFDETRSSETSPYLLSS
VKP-----QTLASRASPDINAVKKQEMPRSEL-----------APE--------------
---------RHTVHTIQTSKDHTS-----DVPKQSVLVSK----HQLEAVEDTGVKEPLS
SAKSNYA-QFI-----SNASASNADKRVSTKEMSKEPEDMYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKLSFKTI-
PLPDDSEAVACHETLK-SRL---EDSDEKVTPLKE-NKQKETH---------KTEEVLST
DSEIGDLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
TEEMISFPVSSVESALEHEYDLV-KLDECFYGPEKDHDVL-SHPETQKFLGIQKSAD--R
SVS-KDIKRDVDSKSLGMPLFEAEEGVLSRTQIFPTTIKAVNPELLEEPPALAFLYKDLY
EEAVGEKKKEEETVSEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSITQKD
QDQGMEEKRVGKDDSYRTIAA--EGEIW---GNFGTIHEEKGLE-EQ-KAVYGEGESVGH
VEILGNIA-MQKTAPITEEVRVATQK-ISYAVPFEDTRHVLERTDEA-------------
-------GSQG------NE------VG---------NANPEVNLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKVLVPPEPSEE--RLRNSPVQDEYEFAESLHYEVVPQ-GVLSEE-LS
SESTPEDVL-SQGKESFEHIS--ENEFVSEAEQSTSAAQKELGSERKEQDQLSSE-FVTE
KAQKEPKKSQIDTYCYTCKSPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVTVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPAT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPSDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGTLGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLVFINAESGQLLFVIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------DGDEEATRELETEEESE----GEEDET----AAESEEEPDS-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNRKRNSFESQ-DVP
TNKKGSPLTSASQVLTTEKEKSYT---GIYDKARK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSGSNTVSKTRKL-----VAQSIED-----------------KVKEVFPPWRGALSKG-
----------SESLT---------LMFSHEDQ-KKIYADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPD-TPATMF--LRTTKEECELASPGTAASENDSSVSPSFANEVKKED
MYSAHHSIS------LEA-------VSPGLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------IERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENMLEPSISLSEPLMLEEPE
KEEIETSLPIAITPEPEDSNLVE-EEIIELDYPESPLVSEKPFPPHM-SREVEH------
------------------------------------------------------------
---------------KEEELILPLLAAS-------------SSEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELQE----QEG------------------
----------------EPVPPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAAPASER--------------------------------------SLSPSTTEKTSEN
QSPLFSTVTPEHMVLSGDEASES-----GCYTPDSTSAS--------------EYSVPSQ
ATKQSL--KQTIDHKSPLIS--KGVSEYMIPSEE-KEDTGSFTP---AVAPASEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSERFTPDSKLISKYAAPLNATQESQKKI
INEASQFKPKGISEHTVLSVDG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
PSSPDL-VVASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEEA
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPMNLSEED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKAETFPLMSP--LEDLSLPPSTD--KS
EKAEIKPEIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPSHLT-------
--------S---EVEKGEREAS-SSVAAIPA--ALPAQSFIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--VPESEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSKNEP---EVIKPYSP
LKETSLSGP----------------------------EVLS----------AVKMEMKHY
SKITTTP----IVLHSASSGVEKQVE---------------------------------H
GPPA--------LAFSALS--EEIKKEIEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTRAVKEEIPTDS-------
-----------------------------------SLVTPVDR-PVLIKVGK-------G
ELGSGLP----------------PL--VTSADDHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSLPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------HSDKSEEARVE------DKQDL
LFSTVCDSERLVSSQKKSLMSTSEVLEPEHELSLSLWGEIKKKETELPSSQNVSPASKHI
IPKGKDEETASSSPELENL-ASGLAPTLLLLSDDNNKLAVEVSSTAQGDFPSEKQDVALA
E-----LFLEPEKKDKPHQPLELPN---AGSEFSSDLGRQSGSIGTKQAKSPITETEDSV
LEKGPAELRSRE-GKEENRELYA--SSTM-PAISELSSLLREESQNEEIKPFSPKIVSLE
SKEPPASVAEGGNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DILDKLSEETGHSN--SSQVLQSITEPSKIAPSDLLVEQKKTEK----ALHSDQTVKLPD
VS-----TSFEDKQDLGIKQFSLMRENLPLEQSKSFMTTKPVDVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEQRIAGSVQLDSSGS--NELRPGQLKAAV----------------
-SSKDHTCEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVDTLSSKSYSSEEVKL-AEEP
KSLVLAGNVERNIAEGKEIHSLMESESLLLEKANTELSWPSKE-DSQEKIKLPPERFFQ-
KPVSGLSVEQVKSETISSSVKTAYFPAEGVEPAL-GN---EKEAH-RSTPPFPEEKPLEE
SKMVQSKVIDDADE-----GKKPAPEV-KIPTQRKP-ISSIHA--REPQSPESPEVTQKP
PTQPKVA-KPDLPEEKGKKGISSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPSPSVEK
AVTVI-DPEGTI---P-TNFNVAEKPADHSLSEVKLKTADEPRGTLVKSGDGQNVK-EKS
MILSNVEDLQQPKFI---SEVSREDYGKKEISGDSEEMNINSVVTSADGE-NLEIQSYSL
IGEKLVMEEAKTIVPPHVTDSKRVQKP------------AIAPPSKWNISIFKKEPR--S
DQ-----------------------------------------------------NQKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKPESIILPVEESKGSLID
FSEDRLKKEMQNPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVLAEKQNSV-AP
LELRDSNEIGKTQITHGSRSTELKESKADAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEGKKQQEHQPYSVNVAESMSRESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLP--------VTLSCRDEIE
NHSLSQEGNLVL------------------------------------------------
------------------------------------------EKSSRDMPDHSEEKEQ-F
RESELWKGGSVDITKESMKEG----------FPSKESERTLARPFDETKSSETPPYLLSP
VKP-----QTLASGASPEINAVKKKEMPRSEL-----------TPE--------------
---------RHTVHTIQTSKDDTS-----DVPKQSVLVSK----HHLEAAEDTRVKEPLS
SAKSNYA-QFI-----SNTSASNADKMVSNKEMPKEPEDTYAKGEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDE--KVTPLKE-NKQKETR---------KTKEEIST
DSET-DLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
TEETISFPVSSVESALEHECDLV-KLDESCYGPEKGHDIL-SHPETQS----QNSAD--R
NVS-KDTKRYVDSKSPGMPLFEAEEGVLSRTQIFPTTIKVIDPEFLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGKDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVDH
VETIGNVA-MQKKAPITEDVRVATQK-ISYAVPFEDNHHVLERADEA-------------
-------GSQG------NE------VG---------NASPEVNLNVPVQVSFPEE-EFAS
GATHVQETSLEEPKILVPPEPSEE--RLRNSPVQDEYEFTESLHNEVLPQ-DILSEE-LS
SESTPEDVL-SQGKESFEHIS--ENEFASEAEQSTSAEQKELGSERKEEDQLSSE-VVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFGERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLIFINAESEQLLFIVRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HTGESFLGS-------DGDEEATRELETEEESA----GEEDET----AAESEEEPDT-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
QEGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKRGSPS--LRRKGNKKRNSFESQ-DVP
TNKKGSTITSASQVLTTEKEKSYT---GIYDKARK----KKTTSNTPLITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKD--TSISLEPDL
DNSGSNTVSKTSKL-----VAQSIED-----------------KVKEVFPPWRGALSKG-
----------SESLT---------LMFSREGQ-KKIYADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPD-TPATMF--LRTTKEECELASPGTAASENDSSVSPSFANEVKKED
VYSAHHSIS------LEA-------ASPGLAASTQDD----LNPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------IERAEPVSA------------
--KLTPT-----------HPNV-------------KGEKEENMLEPSISLSEPLMLEEPE
KEEIETSLPIAITPEPEDSNLVE-EEIIELDYPESPLVSKKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------KEEELILPLLTAS-------------TPEHVASSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELQE----QEG------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEELEAYS
LAAAPASEH--------------------------------------SLSPSTTEKTSES
QSPLFSTVTPEHMVLSGDEASES-----GCYTPDSTSAS--------------EYSVPSQ
ATKESL--KKTIDHKSPLMS--KGVSEYMIPAEE-KEFTGSFTP---AVAPASEPFLSPS
TTEKTSECQSPLPST-ATSEYVVPSEGED-LGSERFTPDSKLISKYAAPLNATQKSQEKI
INEASQFKPKGISEHTVLSVEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
PSSPDL-VVASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEEA
V-----ELERYTPSST---------SAS-EFSVPPYATLEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPMNLSEED--QEDIGPFSPDSAFVSEFSFPPCVTQEAEKRKFECDSPICLTS
PSEHTILSDEDIEGAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAMSASGYSCF
SEADEEAI-GSIAA---TPV-SEQFS--SSQKQKAETFPLMSP--LEDLSLLPSTD--KS
EKAEIKPEIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLMPPHLT-------
--------S---EVEKGEREAS-SSVAAILA--SLPAQSPIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--VPGSEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSKNEP---EVIKPYSP
LKETSLSGP----------------------------EVLS----------AVKMEMKRD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPPA--------LAFSALS--EEIKKEIEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEIPTDS-------
-----------------------------------SLVTPVDR-PVLTKVGK-------G
ELGSGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAL--SEAE-----KEIK-------FDSLPSVSSIVEHSVLS
EVEAKEVKAGLPLIKTSSSQ------------------HSEESEEARVE------DKQGL
LLSTVRDSEHLVSSQKKSLVSASEVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENL-ASGLAPTLLLLSDDKNKQAVEVSSTAQGDFPTEKQDVALA
E-----LSLEPEKKDKPHQPLELPN---AGSEFSGDLGRQSGSIGTKQAKSPITETEDSV
LEEGPAELRSRE-GKEENRELYA--SSTM-PAISELSSLLREESQNEGIKPFSPKIVSLE
SKEPPASVAEGGNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DILDKLSEETGHPD--SSQVLQSITEPSKIAPSDLPVEQKKTEK----ALHSDQTVKLPD
VS-----TSFEDKQDLGIKQFSFMRENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPGQLKAAV----------------
-STKDHTYEVRKQVLPHSAEESHLSSQEAVSALDTSSGSVETLSSKSYSSEEVKL-AEEP
KSLVLAGNVERNIAEGKEIHSLTESESLPLEKANTEFSWPSKE-DSQEKIKLPPERCFQ-
KPVSGLSVEQVKSETISSSVKTAHFLAEGVEPAL-GN---EKEAH-RSTPPFPEEKPLEE
SKMVQSKVIDDADE-----GKKPAPEV-KIPAQRKP-VSSIHA--KEPQSPESPEVTQKP
PTQPKVA-KPDLPKEKGKKGISSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPRPSVEK
AVTVI-EPEGTS---P-TNFNVAEKPADHSLSEVKLKTADELRGTSVKSGDGQNIK-EKS
IILSNVEDLQQPKTI---SEVSREDYGKKEISGDSEEMNINSVVTSADGK-NLEIQPYSL
IGEKLVMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KQKSL
LSFDVVGKVPQQPKSASSNFASKNI------------TKESEKPESIILPVEESKGSLID
LSEDRLKKEMQNPTSLKISEEETKLRSVSPTEKKDNLENRSYSLAEKKVLAEKQNSV-AP
LELRDSDEIGKTQITHGSRSTELEESKADAMPQHFYQN-EDYNERPKIIVGSE----KEK
GE---EKENQVYVLSEGKKQQEHQPYSVNVAESMIKESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLSEAHPEFREAKAVGTQPHPLEESKVLVEKTKIFLP--------VVLSCHDETE
NHSLTQEGNLVLE-----------------------------------------------
-------------------------------------------KSSRDMPDHSEEKEQ-F
RESELSKGGSVDTTKESMKQG----------FPSKESKRTLAHPFDETKSSETPPYLLSS
VKP-----QTLASGPSPEINSVKKQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTS-----DVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----SNTSASNADKMVSNKEMPKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDE--KVTPLKE-NKQKETH---------KTKEKIST
DSETGDLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
TEETISFPVSSVESALEHEYDLV-KLDESFYGPEKGHDIL-SHLETQS----QNSAD--R
NVS-KDTKRDVDSKSPGMPLFEAEEGVLSRTQIFPTTIKVINPELLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRSSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGKDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVDH
VETVGNVA-MQKKAPITEDVRVATHK-ISYAVPFEDTHHVLERADEA-------------
-------GSQG------NE------VG---------NASPEVNLNVPVQVSFPEE-EFAS
GATHVQEIPLEEPEILVPPEPSEE--RLRNSPVQDEYEFAESQHNEVVPQ-DILSEE-LS
SESTPEDVL-SQGKESFEHVN--ENEFASEAEQSTSAEQKELGSERKEEDQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKMFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLKIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEDPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDQCY
KVWVMA----VNFTGCSLPSERAIFRTAPSTPVIHAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMHCSDPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLIFINAESGQLLFIVRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------DGDEEATRELETEEESE----GEEDET----AAESEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVQKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKGSPLTSASQILTTEKEKSYT---GVYDKARK----KKTPSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKG-
----------SESLT---------SMFSHEDQ-KKICADSRLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPG-TPATVF--LRTAKEECELASPGTAASENDSSVSPSFTNEVKKED
VYSAHHSIS------LEA-------ALPDLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVPA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIDTSLPVAATPEPEDSNLVE-EEIIELDYPESPLVSEKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPEHVALSEEERE----EI
ASVSTDSAFISEYSVP----------QDLNHELEK----RES------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSPLFSTVTPEHMVLSGDEASES-----GCYTPDSTSAS--------------EYSVPSQ
ATKESL--KKVIDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTL---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSECFTPDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKGISEHTVLSVEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
PSSPDS-VVASEHS-FPP--------HTTEVTSECQAPPL-----SATPSEYVVLSDEET
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFASEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKSETFPLISP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSASVSEYLILAQK-------QKTQAYL-EPESEDLIPPHLT-------
--------S---EVKKGEREAS-SSVAAIPA--SLPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTVK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--IPGFEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSENEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSALS--EEIKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVGH-PVLTKVGK-------G
ELGSGLP----------------PL--VTSTDEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------YSDESEEARVE------DKQGL
SCSTVRDSERLVSSQKKSLVSTSAVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENS-ASGLAPTLLLLSDGKNKQAVEVSSTDQGDFPSEKQDIALA
E-----LSLEPENKNKPHQLLELPN---AGSEFASGLGRQSGSIGTKQAKSPITETGDSV
LEKGPAELRSRE-GKEENRELYA--SATM-PTTSELSSLLREESQNEEIKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLLVEQKNTEK----ALHSDQTIKLPD
VS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEELKLLAEEP
KSFVLAGNVERNIAEEKESHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVKTTHFLAEGVEPAL-GN---EKEAH-RSTPPFSGEKPLEE
SKMVQLKVIDDADE-----EKKPAPEV-KIPTQRKP-ISSLHS--EEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKGKKGISSFKSWMSSLFFGSNTPDRKVAEQ-EDL-ETLPSPSVEK
AVTVI-EPEVTI---P-TNFNVAEKQADHSLSEVKLKTADESRGTLVKSGEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEMNINSVVTSADGEKHLEIQPYSL
IGEKLIIEEVKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKSESIILPVEESKGSLVD
LSKDRLKKEMQNPTSLKISEEETKLRSVSPTETKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNEIGKTQITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEEKKKQEHQPYSVNVAESMIKESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSDA---------------------------
-----MLSDAHPEIREAKAVATQPHPLEESKVLMEKTKTFLP--------VALPCRDEIE
NHSLSHEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMPDHSEEKEQ-F
RESELSKGGSVDITKESMKQG----------FPTKESERTLAYPFDETKSSETPPYLLSS
VKP-----QTLVSGDSPEINAMKKQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTF-----DVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTV-
PLRDDSETVACHKTLK-SRL---EDSDEKVTSLKE-SKQKETR---------HTEEKTST
DSETGDLSFIQSTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEDKLSEEV
TEEAISFPVSSVESALEHEYDLV-KLDESFYGPEKDHNIL-SHPETQKSL-----AD--R
NVS-KDVKRDADSKSPGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVGH
VETLDNIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPEVSLNVPVQVSFPEE-EFAS
GATHVQETPPEEPKILVPPEPTEE--RLRSSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAEQKELGSEWKEENQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKVSGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----VSL--------YSPDR
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLSS------------------YYFEIHSMNHWSSWQCFNPIF
SPAI--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNRKRNSFESQ-DVP
TNKKGSPLTSASQVLTTEKEKSYT---GIYDKARK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSGSNTVSKTRKL-----VAQSIED-----------------KVKEVFPPWRGALSKG-
----------SESLT---------LMFSHEDQ-KKIYADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPD-TPATMF--LRTTKEECELASPGTAASENDSSVSPSFANEVKKED
VYSAHHSIS------LEA-------VSPGLAAFTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------IERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENMLEPSISLSEPLMLEEPE
KEEIETSLPIAITPEPEDSNLVE-EEIIELDYPESPLVSEMPFPPHM-SREVEH------
------------------------------------------------------------
---------------KEEELILPLLAAS-------------SPEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELQE----QEG------------------
----------------EPVPPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAAPASER--------------------------------------SLSPSTTEKTSEN
QSPLFSTVTPEHMVLSGDEASES-----GCYTPDSTSAS--------------EYSVPSQ
ATKQSL--KQTIDHKSPLIS--KGVSEYMIPSEE-KEDTGSFTP---AVAPASEPSLSPS
TSEKTSECQSPLPST-ATSEHVVPSEGED-LGSECFTPDSKLISKYAAPLNATQESQKKI
INEASQFKPKGISEHTVLSVDG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
PSSPDL-VVASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEEA
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPMNLSEDD--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKAETFPLMSP--LEDLSLPPSTD--KS
EKAEIKPEIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPSHLT-------
--------S---DVEKGEREAS-SSVAAIPA--ALPAQSFIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--VPESEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSKNEP---EVIKPYSP
LKETSLSGP----------------------------EVLS----------AVKMEMKHD
SKITTTP----IVLHSASSGVEKQVE---------------------------------H
GPPA--------LAFSALS--EEIKKEIEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTRAVKEEIPTDS-------
-----------------------------------SLVTPVDR-PVLIKVGK-------G
ELGSGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSLPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------HSDKSEEARVE------DKQDL
LFSTVCDSERLVSSQKKSLMSTSEVLEPEHELSLSLWGEIKKKKTELPSSQNVSPASKHI
IPKGKDEETASSSPELENL-ASGLAPTLLLLSDDKNKLAVEVSSTAQGDFPSEKQDVALA
E-----LFLEPEKKDKPHQPLELPN---AGSEFSSDLGRQSGSIGTKQAKSPITETEDSV
LEKGPAELRSRE-GKEENRELYA--SSTM-PAISELSSLLREESQNEEIKPFSPKIVSLE
SKEPPASVAEGGNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DILDKLSEETGHSN--SSQVLQSITEPSKIAPSDLLVEQKKTEK----ALHSDQTVKLPD
VS-----TSFEDKQDLGIKQFSLMRENLPLEQSKSFMTTKPVDVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEQRIAGSVQLDSSGS--NELRPGQLKAAV----------------
-SSKDHTCEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVDTLSSKSYSSEEVKL-AEEP
KSLVLAGNVERNIAEGKEIHSLMESESLLLEKANTELSWPSKE-DSQEKIKLPPERFFQ-
KPVSGLSVEQVKSETISSSVKTAYFSAEGV-----GN---EKEAH-RSTPPFPEEKPLEE
SKMVQSKVIDDADE-----GKKPAPEV-KIPTQRKP-ISSIHA--REPQSPESPEVTQKP
PTQPKVA-KPDLPEEKGKKGISSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPSPSVEK
AVTVI-DPEGTI---P-TNFNVAEKPADHSLSEVKLKTADEPRGTLVKSGDGQNVK-EKS
MILSNVEDLQQPKFI---SEVSREDYGKKEISGDSEEMNINSVVTSADGE-NLEIQSYSL
IGEKLVMEEAKTIVPPHVTDSKRVQKP------------AIAPPSKWNISIFKKEPR--S
DQ-----------------------------------------------------NQKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKPESIILPVEESKGSLID
FSEDRLKKEMQNPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVLAEKQNSV-AP
LELRDSNEIGKTQITHGSRSTELKESKADAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEGKKQQEHQPYSVNVAESMSRESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLP--------VTLSCRDEIE
NHSLSQERNLVLEK--SSRDMPDHSEEKEQFRESELSKGGSVDITKEIVKQGFQEKAVGT
QPHPLEESKVLVEKTKTFLPVVLSCHDEIENHSLSQEGNLVLEKSSRDMPDHSEEKEQ-F
KESELWKGGSVDITKESMKEG----------FPSKESERTLARPFDETKSSETPPYLLSP
VKP-----QTLASGASPEINAVKKKEMPRSEL-----------TPE--------------
---------RHTVHTIQTSKDDTS-----DVPKQSVLVSK----HHLEAAEDTRVKEPLS
SAKSNYA-QFI-----SNTSASNADKMVSNKEMPKEPEDTYAKGEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDE--KVTPLKE-NKQKETR---------KTKEEIST
DSET-DLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
TEETISFPVSSVESALEHEYDLV-KLDESFYGPEKGHDIL-SHPETQS----QNSAD--R
NVS-KDTKRYVDSKSPGMPLFEAEEGVLSRTQIFPTTIKVIDPEFLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGKDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVDH
VETIGNVA-MQKKAPITEDVRVATQK-ISYAVPFEDNHHVLERADEA-------------
-------GSQG------NE------VG---------NASPEVNLNVPVQVSFPEE-EFAS
GATHVQETSLEEPKILVPPEPSEE--RLRNSPVQDEYEFTESLHNEVLPQ-DILSEE-LS
SESTPEDVL-SQGKESFEHIS--ENEFASEAEQSTSAEQKELGSERKEEDQLSSE-VVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSLARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFGERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLIFINAESEQLLFIVRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MAS---G-----
--GGADGADGA-------DRDEEAPRGPASLEGSE----GDESEE----ESEEEEEPDA-
-SLSDQDEEGKTKQKCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
LEGSTL-NSPPGNVSFIVDEVKKVRKRAPK--SKRGSPS--LRRKSNKKRNSLESQ-DVP
ANTKDNSLISESQVLKTQKEKSST---GIYDKMRK----KKTTSSTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDM
SNLDSNIVSPTGKL-----VAQSIEDD----------------KVKELASPWKAALSKG-
----------SESLT---------SIFSHEDK-KKIYVDSPLKAT--SVTK---------
-----------------HTVSSHASNDTAE---QEVQLSPPQSV----------PQQPGN
EAKLLEMEPSSPIPD-TSTTGF--LETAKEEFEPDLQEIVTSEHDFSILPPLVDEVKKED
VYSADHSIS------LEAEKDSLETGALGLAASIQED----FGIETE--DLTSP------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------ERAEAVSE------------
--QQTPP-----------HLDV-------------KGMQKENIPEPPISLSEPPVLEEPR
REEVETSLPIAATPEPEDSNLVE-EEIIELEYPESPSISEKPFPPYL-APEVEQ------
------------------------------------------------------------
---------------KEEKIFLPSLKTS-------------IPEHVASSEEERE----EN
ESVSTDSAFVSEYSVP----------QDLNHELER----QEV------------------
----------------ESVSPSTVKGVSEHATFS---------------EEENEEFETL-
---ASVSER--------------------------------------SLSPSTTEQTFEC
QAPLFST-----------------------------------------------------
------------------------------------------------------------
----------------ATLEQGVLSEVED-LGSEHFIPDSASTFQNAVPPSAVQEPSKKI
IDDVSPLKSKGISEHMILSEEK--------------------------------------
------------------------------------------------------------
---------KEDTGLYSPDVASVSEHFLPPSTTEQTSECQAPLFSTA-TLEQGVLSEV-E
DLGSKHFTPDSTSTFQNAVPPSAVQEPS-KKIIDDVSPLKSKGISEHMILSEE-KKEDTG
LYSPDV-ASVSEHS-LPP--------STTEQTSECQALPF-----AATSSEHVVLSE-ET
V-----EM-EYTPSST---------STS-EFSVPPYATPESQEEEIVHRSPLNLK-----
------------------------------------------------------------
----GASSPTNFSEEE--QEDIGPFSPDSAFVSEFSFSPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEIELFSPDSAS--QVSIPPYRIPETKKNESEHDSLVTEISASGYFCS
SEADEEDI-VLTAA---TPV-PEHLS--SSQKQQDKPSPSMSA--PED--LRPSTN--KR
EITGVQPDAQTTSTSVSEYLIWTQQ-------QVTRAFS-ESESEDSISPYLT-------
--------S---ETEKGEIQTS-SSVVATPV--SLPAQSLPVKEDTKPVLHSAQYSVSPD
SV-------------------HALPKEQEAKASLTPK---------AANEQM--------
-ALLKVK--------------SKEEIVPDSQEATAHIS------RD---QEMEPQPPN--
--VLGSGMKYSVLPDS-VD-----------------------------------------
-------------------EPKKDVKPNLAPNVTS--ELEPRMLSENEP---EVIKPYSP
LKDTSLSGP----------------------------EILS----------AVKMQAKHD
PKIADTS----RALHSTPPRVQEETE---------------------------------P
GPPA--------PE---FS--EERKEEIEPSCSITTTS-VTQ---------HDS------
------------------------------------------------------------
---------------------------------------SLTKLAREETPTDL-------
-----------------------------------SFTMPIEH-PVVTEVEK-------S
ELGSGLP----------------PL--VTSIDEDSLF-KEEKKVA---------------
---RK-TTSPTETAASERPAW--SEAE-----KEIK-------FDSLTRISSLPEHS-LS
NVETEEVKPGLPITKALSSQ------------------RSDVSKDERVE------NEQGL
SFATVLNSEQLVLSQKKNSVSASEVSGPEHVLLLNKGGEVKKKEIELPSSQNMSPVPKHT
VLKDKNEEMESSSPELENLVSADLTS---TPRDDKNRQTVEPSSTAQGDFLSEKQDLSLA
E-----LSLELEKKDRPHQVSELPS---AESEFTCSLGGQDGSIDTKQIKSPITETEDSV
LEKGFAEFGGRGEGKEENREHHV--PATVDPKISEVLSCLEEEPQIQEVKYFSPKVVSLG
SKEALTPLVEGDSFKELQPHTFSLKGLSEKLNHLADIKSGEKQEISPLLSTGIPKTQVIG
DAEMKPSEERDQPN--LFRVPQSIIEPSEVVSSDLLEEQQKPGK----ALHSDQAVKLPD
VS-----MSFADKQDLGVKQLE--------------------------------------
-----------------------------------------AAL----------------
-LDKDHTCETGKQPLPHSEE-IPLSLQEPVSTLSVTSGDMEALSTKMYSSEEIKL-APKP
KSLVPIGNVEINEAEGKQIFSFIRSESMILEKVNTESSRPCKE-VSQEEIKLPSERIFQ-
KPASGPSMEEIKSETIPSSAKAAHFLAEDAELAS-GN---EKEAH-RSISPLPGEKPLEE
AKMIQSKAVDDVNE-----SGKPASEV-KIPTPIKP-LSSIQD-SEEPQPTEPPEVTQKL
PEQPKAV-EPVLSEEKGKKGILSFTSWMSSLFFGSSTSDKKVAE--KDL-ETQPSPSVDK
AVPMA-ESEGAA---P-ADFNATKKPADHLLPEAKLKPAEKSRGTLVKSGEGRDSE-EKP
TFLSNVEVLQQPKSI---FEVSSEDYGKKEIRDYSEEMDLNLVAASGDGEEHHEIQSYSP
MGEKSNADEVQNAVPLHITDSKKAQKP------------EISAPSKWNISILREEPR--S
DQ-----------------------------------------------------KEKLL
FSFDAVDKVPQQPKSASSSFTSKNI------------TKESEKPETIILPVEESKCSLID
LGEDRLKKEMLKPTSLKISEEETKLRSVSPTEEKGDLETRSYSLAERKVLAEKQETV-VP
LEFRD-NKIGKAQIAHGSSPIKLEESKAAAVLQQVSQN-EDHKERYTIMKQEK-------
----EEKQKLSQVFSEGKQQQEIQPYSVNVVRSVPEESNI------------------S-
--LCPSLD-E-----TQPFSLVKTVSVTEKSGT---------------------------
-----VLLEAHPEIRETRAVGTQPHSREESKVLVEKTKTFLP--------VDLPYPDERD
SHSLPQEGNLTLEK----------------------------------------------
--------------------------------------------SSRDTASHNEEKGQ-D
TVAEPSEGSSIDITKESMKQG----------SPSKESERILDHPFDETKSLETPPYLLSS
VKS-----QTLVSGTSPEISTVKKQEMSLSEL-----------TPE--------------
---------GHTVHTLQTSKDLTS-----EMFKQSVLVSK----HHMEAEENAHVSEPGS
SASSNYA-QFI-----KNASAINAGRMAPPREISEKPGDTYAKDEDF-------AVTSKP
AGL---SEDQKSAFSIISEGCEILNIHASAFISSVDQEESEQMQDKLEYLEEKASFKTV-
SLHDRSEAVSCHKSLK-TTL---EDSDQ-VTSLQE-DKQKESL---------TLKGEIPT
DSETDDFTLNQPTV----PS-EEDYFEKYTLIDYNISPDPEKQKAPWKSN-VEVELPKAV
TEETVSFPESSEESALEHEYDLV-KLDESFYGMEKDYSKL-SHPETQKPLDTRQSAD--K
DAA-KSINRDVDLKSPGMPLFGAEEGVLSRTQIFPTTTKAINPELLEEPPALAFFYEDLY
EQAVGEKNKEEETASEGDSVKSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTQKD
QGQGLEEKTFGKDDSYQSIAV--EGDIW---GRSGTILGEKSLEEKQ-KATYGEGESVGL
LETLDNEA-LQGKTPISEEVTVVTQM-VSYAVPFEDTHHVLERAGET-------------
-------SSQN------NE------AA---------SASPEVNLNVPVQVSFPEE-EFAS
GITCVQETLQEEPKIMVPPEPSED--RLHSSPVQDEYEFAESPNYEMVAQ-DTLSEE-LY
SEPTPEDVL-SQGKESFEHVS--ENEFVSEVEQSMSAEQKELVREKTEQEQLSSE-LATE
KEQKELKKSQIDTYCYTCKSPISAVDQMFGMHKDHEVATLDTAISAVKVQLAEFLDNLQE
KSLRIEAFVSQIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLESIVREAEELDE--TVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATGTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NDLVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIHAEDCTVCWNTATIRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVKAINAFGASEQSEAAL
ISTRATGTRFLLLRETAHPALQISSNGTVISFTERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSHSAVQ-AATLGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPTRVGILLDYNNQRLLFINAESGQLLFIIRHKFNEGVHPAFALEKPGKCTLHLGMEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------S-
-RLSDQDEEGKTTQECIISDPSFSMVTVQREDSGITWETNSNR-STPWASEESQTSGVCS
PEGSTV-SSPPGNVSFIVDEVKKAPKRTHK--AKRGSPS--LRRKGNKKRNSSESQ-DAP
ANKKDNPLISESQALNIEKEKSYT---GVHDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKE--ASISLEPDL
GNYDSKTVSKPGKL-----GARSIEEE----------------KLKELAPPWREALSKG-
----------SKSLS---------SLFSHESQ-KKTDADSPLNAT--SASE---------
-----------------HTVSSYSSNDTEE---LEPQLRP---------------PRPES
EAKPHEMEPSSLSPA-APPRVF--LKTAKEESEAASQGATTPATGSL-----VDGGKQEE
GRSAHLATP------LEAEQDFLETGSPGLAASTQEG----FGPDKEQLDLPS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSD------------
--QLLPP-----------HPSV-------------KGETEGSVPEPP----EPLVSGEP-
EREVETALPVAAAAEPAGSELA--EEIIELDDAGSLLVSEKPFLPTL-SPEVAH------
------------------------------------------------------------
---------------KEEEPVPPLLTAS-------------TPARVPPPEEERE----EN
ESVSPDSAFVSECSGA----------PGSNYELEE----QET------------------
----------------EPVSPPKVKTMTEHVVLS---------------EEEKEELKPHS
PAVLSASER--------------------------------------SLSPSTAEKTSER
QSPLFSSVTPEHVVLSGDETSES-----GRYTPDSTSAS--------------EHSVPSQ
ATEESL--KKTTDHKMPLKP--KGVSEPMVLSEEEKEDIGSQSP---AVGSQSERSLSPS
AAEKTSECQSPLFSS-VTPEHVVLSGEET-SESEDIGSQSPAVGSLSPST------TEKT
SECQSPLFSSVTPEHVVLSGDE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------TSESG
RYTPDS-TSASEHS-VPSRATEALLKKTTEMTSECQPPPL-----SATPSERVVPSEEEA
V-----EMERYTPSST---------SGS-EFSVPPPITPEPQEEKIVHDLPLNLE-----
------------------------------------------------------------
----SASSPKSLSEAD--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPMCLTS
PSDHTILSDEDTEEAGLFSPDSVS--QISIPPFRVPATEINEIEPDSLLTAMPASEYSCF
SETDEEEI-GSTAS---TPV-PEHFS--SSQEQKAEPFPLISV--LEDLSLPPSRN--KP
EKAEVKPDIPTTSTSVSEYLILAHK-------NKTQASL-EPESEDLIPPCSN-------
--------S---ELEKGETRPS-PSVAATPA--SLLAPSSMVKEETKPVLPARQCSVSPD
SV-------------------HAIKKEQEPKSSLTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATPHVS------QD---QKMEPQPPN--
--VPGSEMKYSVLPEL-EN-----------------------------------------
-------------------EPKKDVKPNLAPNVTS--EQEQRILSKNEP---EVTKPYSP
LKETFLAAP----------------------------EVVS----------VVKTEVKRD
PKIMSTS----MEPYPASLGVVKEVE---------------------------------H
GPPA--------PAFFSAL--SEVNKETKPSSSTT-AS-ETT---------LES------
------------------------------------------------------------
---------------------------------------NLTKSVKEEIPTDV-------
-----------------------------------SFASPVEH-PVLTKGGK-------G
ELGSGLL----------------PL--VTSIDEHSVL-KEE-RAG---------------
---IK-DASPIETSSSKVLAW--LEAE-----KEVK-------VASPLSVSSMSEHSVLS
KVETEEIKPE-PISQTPSAQ------------------RSDASEGAKVE------DKQGL
SLSAVIDSECSVLSQEKD----SEASEPEHVFSLNLGGKLKKEDPELLLSQNVSPPPKPI
VQKGNSEEIASSS-ELENLVSEDLAPTLPTPGDDKSKQAMEPAPTAQGDFPSEKQGVGLA
E-----LSLEPEKKEQLCQPSEFPN---AESEITHGLGRQSRSIDKKQIKSPIIETGGSV
SEKDLAELTGRK-GKEENKELQA--SAKV-PAVAEVSSCLREEAQKEETKPFSPEGVSLR
S--------KGDHPEELQPYLFSLKGLSEQLNHSADFQKEEDQEISSLPPIGNLKAQMTE
DIVTKPNEDTGHPK--SACVVQSVTEPSKITPPDLVG--RKTEK----ALRSDQAIKLPD
IS-----TSPTDKQDLGIQQLSFTKENLPLEQPKLYMITKPADLKETKMKESFISLKD-E
KTMLEKPENL-ASQHEERTPGSVQLGSSDS--SDVMSRQPK-AL----------------
-SDEDQPWAGRKQVPPHSAEETPLSLQEPVPALDISSGDEETLLSKSYPFEAVKL-AQEP
KSLEVAGNEERTTAEGEEVYSFMGSESLILEKSSTESSRPRKD-GSQEEIKLPPERVLQ-
TSVSGPSVEQARSETIPSPVTTAHFLAEAEELSL-GK---EAAAH-WGTPPLPGEKPLEE
SKTVQSKVVDDAST-----GEKPAVEA-KMPPQRKS-RSSVPA-GQEPQPQESPEGTQKP
PEQPKVV-KPDLPEEKGRKGISSFRSWMSSLFFGSSTPDNKVAEK-EDL-ETQQSSSVEK
AMTVT-EPEGTI---P-TDFNATEKPAAYSLPGGKLTTAVEFRGADIKSDEGQDFK-AKP
TFSSNTEVVQQPKSD---SEMTAGDYEKKEIPDSSEEMNTNAVVASTDGEEHLGIQSFSP
TGEKLVVEEARNVVPLPARESKRVQKP------------TIAPPSKWNISILQEQPK--S
HH-----------------------------------------------------KDKSL
LSFDVVDKVPPQPESASSVFTSKTI------------TKESETPESIILPVKESKGSLID
LGEDRLKKEMPTPTALKISEEEMKLRSVSPNEEKGNLESRSGILAEEKALVGKQDTV-AP
LELRDENETGKAQITRGSGPTELEESKAASVLQKVHGN-EGHRERSQIMVSSK----EEK
GE---EKENQP---------------PVNVAQSMPKELET------------------S-
--LGRSLG-E-----TQPFSLVKATSITGKSET---------------------------
-----ILSEAPPEIKETKAVGRQPHPLEENKVL-EKTKTFLP--------VALSGRDEIG
NHSLAQEGNLVFE-----------------------------------------------
-------------------------------------------ESSRDVPHPSEERGQ-L
KASELSKGVSVEITKESMKQG----------SPFKELERSVARPLDETQNFETPPYLPSS
VKP-----QTIASGASLEINTAKKQGVPWSEP-----------TPE--------------
---------RHTVHTVQTSTDQKS-----DTPKQSVLVSK----PHLEAVDDTHGHEPLS
SARSNYA-QFI-----TNASAVSTDKMVSTKEMSKGPEDTYTKDEEF-------TVTSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFIFSADQEESEQMPDQLEYLEEKASFKTTL
-PRDDREAVACQKIVR-SKL---EDSEEKVISLKE-NKRKETR---------KTKEEISI
DSETGDLAFIQPTV----PC-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-IEEKLSREV
TEETLPFPESSEETPLEHEYDLV-KLDERFYGPEKDHSKL-SYPETQKSLVIQKSAD--G
NAS-KGTSRDVKSKSPGMPLFDSEEGVLSRTQIFPSTPKAVNPELLEEPPALAFLYKDLY
EEAVGEKMKEGETASEGDSVNSEASFPRRNSDTDDGTGMYFEKYILKDDIPYDTSVTQKD
QGQGLEE-RVGKDDSYQPIAA--EGEIW---GRVGTTLE-KSLE-EQ-KAVYKEEEPVGH
VETLDSVA-MQRKA-VTEEVRVVTQK-MSYAVPFEDTHHVLEPIGEA-------------
-------SSQG------NE------AE---------NASPEFSLNVPVQVSYPEE-EVAS
GATYVQETLQEEPQILVPLEPSEE--RLRNSPVQDEYEFAELPNYEVVTQ-DTSPEE-LY
PESTLEDVS-SQRKESFERIKGCETEFTSEVEQSTSVEQEELSRERKEPNQLSSE-LVTE
KTHTELKKPQIDAYCYTCKSPISATDKASGIHKSHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVSFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINDR
LLSAMESTASLEKMPAAFSLFEHYDDGSARSDQ-MLTQVAVPQPPRLEPQEPNSATGTT-
-IAVYWSRNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRVTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRSAN--PDAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
VSTR--GTRFLLLRETAHPALQISANGTVISFTERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAVQ-AGTLGQGDTSWYMHCSEPQR---YTFFYSGIVSD---VQVT
ERPARVGVLLDYPNQRLLFINAESGQLLFIIRHRFSEGVHPAFALEKPGKCTLHLGIEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASSD------G
S-QAAESALG---------ADEEEIRAPDAE--EQ----SGGEEDESAVESESESEPDA-
-RLSDQDEEGKTKKKCIISDPSFSMVTVQREDSGITWETSSSRPSTPWASEESQTSGVCS
LEGSTL-NSPPGSVSFIVDEVKKVRKRKPK--SKHGSPS--LRRKGNKKRNSFESQ-DAP
ANKTS-------QELTTQKEKSST---GTYDKMRK----KKSTSSTPPITGAIYKEYKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPES
GDRDLKVVSKTGKS-----ATQSIEDV----------------KGKELAPPWRDVFSKG-
----------SKSLT---------SLFGREDQ-KKTYDDFPLRAA--SAAQ---------
-----------------HTASSHTSHAIAE---RESQLSPPRVV----------PQVLTD
EAKPCDTKPSSLAPA-TSVATF--LETAKEESEADSQETVIAEPDSSVSPPVLDEVKTED
MSSIDHSIS------LEAEKGSLESGAPGLTASIQED----FSPGREELDLTSRERAEPV
ADQLTPP-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------HLSI-------------KGEKEETVPEPSISLSEPLVVEEPE
KEETEMPLPMAATPEPEDSSLVEEEEIIELDYPESPSVSEEPFPPHL-APEEEE------
------------------------------------------------------------
---------------KE-ETLLPLLTTS-------------TPEQVALSEEERE----EN
ESVSTDSAFVSEYSAP----------QDWIYELEK----QEA------------------
----------------EPVSLPHVTAVSEHAVLS---------------EEEDDKFEHSS
PTSAS---I--------------------------------------SVSPSTTEKTLEC
QSPLFSAVTPEPTILSGEEGSES-----GRYTPDSTSAS--------------EYLVPSQ
ATEESL--KKTVDLKSPSKS--QGVSEPLILSEEENEDPGLCSP---ELASLPECSLPPS
TTEGTPECQAPPLSA-MTSEHAVLSEGEN-LGNEGVTQD---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------SALTFQNAVPPNVRQESP-KNIIDDVSLLKSEGVSKHKTVLEE-EKEDAG
FYTPEV-ASLPERS-LPP--------STTEGTPECQAPPL-----SAAPPDHVVPSEEET
V-----EMERYTPSST---------SAS-ELSVPPYATPESQEEEIVHTSPLNLK-----
------------------------------------------------------------
----GSSSPMTFSEEE--QEDIGPFSPDSAFVSEFSFPPYAT--TGKREFECDSPICLTS
PSEHTILSDEDTEETELFSPDSAS--QASIPPYRIPEMNRKEIEPDSLLTAMAASGYSRF
SEADEGEI-APTTT---TPV-PERLS--SSQQQRAEP--SMSA--PKDLSQLPSTN--EA
EKAEIKPDAQTTSTSVSEYLILAQK-------QRTRTYS-EPEPEDSVPPRLT---S---
------------DSERGETKSSS-SLAAPP----A--QSPTVKEETKPVLPASQCSVSPD
SA-------------------RAIKKEQEPETSLTPK---------SADEQM--------
-ALLKVE--------------SKEEIVPDSQEAIAHVL------RD---QEMEPQPPNFR
GFIPESGMKDSVLPDL-AD-----------------------------------------
-------------------EPEKDVKPSLAPTATS--ELGQRRLSENEP---EVMRPYSP
LREASLSRP----------------------------EISS----------VVETEVKLD
SKVTGPP----GVLHSTSLGVEQEGE---------------------------------H
GPPVA------E--FSALS--EEIKKEIEPNASITITS-ETK---------HDS------
------------------------------------------------------------
---------------------------------------NLTKLAKEEIPTDL-------
-----------------------------------PLTTPIEH-PVLTKVEK-------S
ELGSGLP----------------PV------DEHSLFKEEGKVAI---------------
---KA-SPSPTETAASQYPAW--SEVK-----KEIK-------FDLPASISSISEHSVVS
EVETEDIKPGLAITKTLSSQ------------------HLDVSKEARVE------DKQDL
SFPTVLDSEYLDLSQKKNYVSASEMSGPEHVPSLSPGGEIKKTETELPSSQNVSPTPKYI
VPKGKDEVTASSPPELEHLTPEDLASTFLTFGGDKREQAVETPSVIQGDFRSEKPGLARA
P-----LSMEPEKRDKTHPVSELPETGSAGSEFAGDVSRQSGSIQTEHIKSPLPETEDSV
LAKGLPELRSRGEGKEENRELHV--STTV-PETSEVSSYLREEPQIQEMKSLSAKVVSLG
SREAFTSRLEGDSLEELQSYALSAKGSSEEPNRSADFKKEEKQEISPLQPAGDLEAQVTE
GTVTKL-NETDQPN--SFHVLQSVAEPSKVASSDLFVQ-QKPEE----ALDSDQAAALPD
IS-----RSFADKQDLGIKQVLFMKENLPLEESKLLLTTEPTDVRETHMKEPLISPKD-E
NWMLKKPERDLVSHHEERVMGSVQLGSSGT--SDLMTGQLKPAL----------------
-PEKDHTPEIRKQILPPSAAEPHLAFQEPVSTLDTSRDNIETLATETYSSEDIKL-APKP
ESLVAAGNVERSEAEVKQTLSFVGGESLVAEKENTEIPRPCKE-DSQEELKIPYEGGLQ-
KPVSGPSMEQVKSETPPSLVKAARVLAEEAEPAL-GV---EKEAH-GRISPLPGEKPLEE
SNVVQPKVADDANE-----RGKPPSVV-KAPTQIKP-LSSTQE-NKEPQPLESPEVIQKP
PKEQKAV-EPSISEEKAKKGISSFTSWVSSFFFRSSTQDNKVAEK-EDL-EAQPSPSEEK
TVTVI-DSEGPA---P-ADVHGTEKPVDHLFPEAKPKTASESADSLVKSGEHHDFK-DKP
ALLSNVEFSPQPKSS---FEASSDDYGKKEVLDYSEEMDLTSVVSSVDGGGHLRIQSYSP
MSEKSIMEEAKNAVPFHVTDSKRLQKP------------EISPRSKWNISILKEEPR--S
DQ-----------------------------------------------------KGKPL
LSVDATDKVPQQPEPASMSFASKTI------------TEESEKLESVILPGEEPKGSLID
LGEDRLGKEMPKPISLKISEEEIKLRSVSPAEEKGTLGMRSYSLAEKKALAEKQETA-AP
LDHREINEIEKAKIIHGPSPVKLEEPKAATVRQQVYQN-EDHKERYKIIEEEK-------
G---EEKEERSHAFSEG-REQEIQPYSISIARHQPEESDI------------------S-
--FRLTWG-E-----TQPFSLVKTTEAAETSET---------------------------
-----TISEAYSEIKETKAVGSQPHPLEEREVLVEETKAFLP--------VDLPYHDEIN
EPSLPKEGNLVLEK--S-------------------------------------------
---------------------------------------------SRDVVTHREEKGQ-V
IVSELPKGGSVGTAKE-SKQG----------SPSKESERILDRPSGETKSLETPSYLLSS
VKP-----QTLASGASPEVSPEKKQEQPLSEV-----------TPD--------------
---------RPTVLTTQTSKDLTS-----EMFEQPVLVSK----HHLEAVEDSQVYEPCP
SASSNYA-QFI-----TNA-TIRADEVV-----SKEPEDTSVRDEEF-------TVTSKP
AGL---SEEQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQDKLEYLEEKISFKPI-
LLHDESEEIACHKTLQ-SKL---EDSDIKVISLKE-DQQKEIH---------TAKEEIPT
DSETGDLAFNQPTS----PD-EEDYFEKYTLIDYNISPDPEKQRAPWKLE---AGLSKEV
PEETVSFPEHSEEGALEHEYDLV-KLDESFYGLEKDYSKL-SDPETQKSLVTQKLTD--R
DAP-KSTDRDVDSKSPGMPLFEEEEGVLSRTQIFPTTAKAINPELLEEPPALAFLYKDLY
EEAVGEQKKEGETASEGDSVNSEASFPSRNSDIEDGTGIYFEKYILKDDILHETSVTEKD
QGQGLEEKPIGKDDSYQPITA--EGEIW---GKFATIDREESLEEKQ-KAAYREGESVGQ
METLDSVA-MQRKAPITEEVRVVTQR-ISYAVPFEDTRHVLERVDET-------------
-------SGQT------DE------AA---------NANPEASVNVPVQVSFPEE-EFAS
GATCMQEALQEEPQIMVPPEPSGD--WVRSSPVQDEYEFAESLNYEVVTQ-DTLSED-LY
SESTPEDVL-SQGKESFEHVS--ENELVTGAEQRKSAEQKELGIEMAEQDQSLSE-LVTE
KEQKEMKTSQIDTYCYTCRSPISAVDTMLGTHKDHEISTLDTAISAVKVQLADFLEDLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKRKKM
EFLHDQMVHFLQSMDTAKDTLETIVREAEELDE--TVFLT----SFE--------EINER
LLSAMENTASLEKMPASFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NDLVEEYRVTVKESYCVFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNSATIRWRPAS--PEAT
ETYTLEYCRQHAPEG-EGLRSFSGIKGLQLKVNLQPNENYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSNGTVISFAERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMQCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYTTQRLLFINAETGQMLFIIRHRLCSLK-ALVATRNPSKDTRNTGA---
------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKGSPLTSASQILTTEKEKSYT---GVYDKARK----KKTPSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKN--ASISLEPDF
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKG-
----------SESLT---------SMFSHEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPG-TPATVF--LRTAKEECELASPGTAASENDFSVSPSFTNEVKKED
VCSAHHSIS------LEA-------ALPDLAASTEDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIDTSLPVAATPEPEDSNLVE-EEIIELDFPESPLVSEKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----RES------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSPLFSTVTPEHMVLSGDEASES-----GRYTPDSTSAS--------------EYSVPSQ
ATKESL--KKVIDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTL---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHMVPSEGED-LGSECFTPDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKGISEHTVLSVEG-KEDI-GPASPDS-------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VIASEHTVLSVE-GKEDIG
PSSPDL-VVASEHS-FPP--------HTTEVTSECQAPPL-----SATPSEYVVLSDEET
V-----ELERYTPSST---------SAS-EFSVPPYAAPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFASEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKSETFPLISP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPSHLT-------
--------S---EVKKGEREAS-SSVAAIPA--SLPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--IPGFEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSENEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSTLS--EEIKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVGH-PVLTKVGK-------G
ELGSGLP----------------PL--VTSTDEHSVL-AEEDKAA---------------
---IK-GASPIETS-SKHLTW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------YSDESEEARVE------DKQGL
SCSTVRDSERLVSSQKKSLVSTSEVLGPEHELSLSLWGEKKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENS-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDIALA
E-----LSLEPEKKNKPHQLLELPN---AGSEFASGLGRQSGSIGTKQAKSPITEAGDSV
LEKGPAELRSRE-GKEENRELYA--SATM-PTTSELSSLLREESQNEEIKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLLVEQKKTEK----ALHSDQTIILPD
VS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEELKL-AEEP
KSFVLAGNVERNIAEEKESHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVKTTHFLAEGVEPAL-GN---EKEAH-RSTPPFSGEKPLEE
SKMVQLKVIDDADE-----EKKLAPEV-KIPTQRKP-ISSLHS--EEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKGKKGISSFKSWMSSLFFGSSTPDRKVAEQ-EDL-ETLPSPSVEK
AVTVI-EPEGTI---P-TNFNVAEKQADHSLSEVKLKTADESRGILVKSGEGQNVK-EKS
IILSNVEDLEQPKSI---SEVSREDYGKKEISDNSEEMNINSVVTSADGEKHLEIQPYSL
IGEKLITEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISVFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKSESIILPVEESKGSLVD
LSEDRLKKEMQNPTSLKISEEETKLRSVSPAETKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNEIGKTQITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEEKKQQEHQPYSVNVAESMIKESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSDA---------------------------
-----MLSDAHPEIREAKAVATQPHPLEESKVLVEKTKTFLP--------VALPCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMPGHSEEKEQ-F
RESELSKGGSVDITKESMKQG----------FPTKESERTLAYPFDETKSSETPPYLLSS
VKP-----QTLVSGASPEINAMKKQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTF-----DVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTV-
PLRDDSETVACHKTLK-SRL---EDSDEKVTSLKE-SKQKETR---------HTEEKTST
DSETGDLSFIQSTI----PS-EEDYFEKYTLIDYNIYPDPEKQKAPQKLN-VEDKLSEEV
TEEAISFPVSSVESALEHEYDLV-KLDESFYGPEKDHDIL-SHPETQKSLGIQKSAD--R
NVS-KDVKRDADSKSLGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVGH
VETLGNIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------HASPEVSLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILVPPEPSEE--RLRSSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAEQKELGSEWKEENQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAVNAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASSDST-----
--YAAESPLGS-------DGDEEAPRRLESDEESE----SEEDET----AAESEEEPDA-
-RLSDQDEEGKTKQKCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
LEGSTM-NSPPGNVSFIVDEVKKARKRMPK--SKRGSPS--LRRKGNKKRNSLESQ-DVP
ANTKDNPLISESQVLSTQKEKSFA---GIYDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKE--ASISLEPDM
SNRDSNIVSQTGRL-----VGQSIEDD----------------KVKQLASPWKAAFSKG-
----------SESLI---------SSFRHEDE-KKIYVDSPQKAT--SGTD---------
-----------------HIASSFASNDTAE---QEIQLSPPESV----------PQQPGD
EAKLCEMEPSSLTPD-TSTPGF--LETAKEEFEPDSQEIVTSEHESSVLPPLVDEVKKED
VYSVDHSIS------LEAEKDSLEIGAPGLAASIEED----FGPEMEELDLTSP------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------ERAEPVSE------------
--QQNPP-----------HLDI-------------KGMEEENVPEPTISLSESLVLDEPK
KEEVETSLPRAATPEPKDSNLVE-EEVIELEYPESPSISKKPFSPYL-APEVEQ------
------------------------------------------------------------
---------------KEE-ILLPSLKTS------------TRSDHVTSSEEERE----EN
ESVSTDSAFVSEYSVP----------QDLNHELEK----QEV------------------
----------------ELVSPSTIKGISEHPIFS---------------EEENEEFEPL-
---ASASER--------------------------------------SLSPSTTEQTSEC
QSPLFSAALSESIGLSGEEASES-----GCYTPDSISAS--------------EYLTPSQ
ATKESP--MKTVDHKSPLKS--KGVSEHVILSEE-KEDTGPYSL---DVASASERSFSPS
AAEQTSESQAPLFST-AMLEQAGMSEEED-QGSERFAADSTLTSQNAVPPNATQEPPKKI
IDDVSLLKSKDVSEHMTFSEEK--------------------------------------
------------------------------------------------------------
---------KESTGLYSPNVASVSEHSLPPSTAEQTSECQGPLFPTP-TLEQAVMSEE-K
DLRSERFTADSTLTSQNAVPTNVTQESP-KKIIDDVSPLKSKGISEHMILSEE--KEDTG
LYSPNV-ASVSEHS-LPP--------STAEQTSGCQAPSF-----AATASEHVVLSE-ET
V-----EIERYTPSST---------STS-EFSVPPHATPESQEEEIVHRSPLNLK-----
------------------------------------------------------------
----GASSPVNFSEEE---QDIGPFSPDSAFVSEFSFSPYATQEAEKRELECDSPICLTS
PSEHTILSDEDTEEVELFSPDSAS--QVSIPPYRIPETRKNEFEHDSLVTKISASGYSCP
SEADKEDL-MPTAA---TPT-PEHLG--SSQKQQAKPSPSMSA--SKDLISPSSTN--KR
EITEVEPDAQTISTSISEYLILTQQ-------QRTQAFS-EPESEDLISPYST-------
--------S---ETEKGEIQTS-SSVAATPV--FSPAQSFMAKEDAKPVLHSSQYSASPD
SV-------------------HEFQKEQETKASLTPK---------AANEQM--------
-ALLKVK--------------SKEETVPDSQEATAHVL------RD---QEMELQPPN--
--VLGPGMKYSVLPDL-VD-----------------------------------------
-------------------EPKKDVKPNLAPTVTS--ELEQRMLSEKEP---EVIKPYSP
LKDTSLSGP----------------------------EILS----------AVKMQVKHD
SEIAGTP----RVLHSVPSGVQEEAK---------------------------------H
GPPA--------PE---FS--KEIKREIAPSCSITTTS-ITK---------HDS------
------------------------------------------------------------
---------------------------------------SLPKSGKEETPTGL-------
-----------------------------------SFTTPIEH-PVLTKVEK-------N
ELGSGFP----------------SL--VTCIDDHSLL-KEEK-IA---------------
---RK-TSFPTETAASEHPAW--SEEE-----KEIK-------FDSPARISSLSEHS-LS
KVETEEIKPGLPITKASLSQ------------------HSDVSKEERVE------NEQDR
SFFTVLDSEQLVLSQKKTSVSASEESGPERVLLLNQGGEVKKKETELPSSQSVSSAPKHI
VPKDKNEEIGSSSPELENLVSADLTL---TPRGKN-REIAEPSSTAQEDFLSERQDLALA
E-----LSLELEKKDKPHQVSELPS---TASEFTRSLGEQDGSIDAKQTKSPITKTGDSV
------------------------------SEISEVSSCLREEPQIQEIKSFSPKVVSLR
SKETLMHLVEGDSLEKPQPHTFSLKGLSEKLNHSADIKTGGKQEISPLLSTGNLKTQVIG
DIERKLSEETDQPD--SFRVPQSVTEPSKMVSSDLV-EQEKPEK----TLHSDQAVKLPD
VS-----GSFADKQGLGVKQFSFLKESLPLEESKSFITTEFADIKETQMQEALFVPKN-E
SWMLEKPERDLASQQEEGILESVELGSSGS--NDLKTGHLKAAL----------------
-LDKDHTCETRKQLLPHSAEESPLSLGEPVCTLSTSSGDIETLSTKTYSSEETKL-APKP
KSLVPTRNVEINEAEEKQILPSVGSESLILEKATPDSSRPCKE-GSQEEIKPLSERIHQ-
KPVSDPSVGEIKSETIPSPTKAAQFLAEDAEPAL-GK---EKEAH-RSISPLPREKPLEE
AKVLHSKVVDDVNK-----RGKPASEV-KISTPIEP-LSSMQE-NEESQLAEPLEVTQKL
PKQQKVV-EPGLSEEKGKKGILSFTSWMSSLFFGSSTPEKKVAE--KDL-EAQPSPSVEK
SSPVT-GSERTA---S-ADSNATEKAADRLLPEAKLKTAEKSRGTSVKSGEGQEFEEEKP
TSLSNVEILQQPKSN---SEVSSEDYRKKEILDYSEEMDLNSVVASADGEKHLEIQSYPP
MGEKSIVEEVQNAVPLHITDSKRAQKP------------EISDPSKWNVSTLKKEPR--S
DQ-----------------------------------------------------REKLL
FSFDAVDKVPQQPKSASSGFTSKNI------------TEESEKPETIILPVEESKCSLID
LSEDRLKKEMLKPTSLKTSEEETKLRPVSPTEEKGDLITRSYSVAEKKVLAEKQETV-AP
LEFRD-NELGKAQT------IKLEESKAVAVLQQVSQN-EEHTERYTIMKQEK-------
----EEKPNQSQVFPDGKQQQEIQPYSVNVVRSKPEESDI------------------S-
--LSPPLD-E-----TQPFSLVKTVSATEKSET---------------------------
-----MLLEGRPEIREPRAVGVQPHPREESKVLVEKIKMFLP--------ADLPYHDEKD
NYSSPREGNLIVEK----------------------------------------------
--------------------------------------------SSRDMASHNEEKGH-V
TVAEPSKGGSIDATKESTKQG----------SPSKESERILDHHFDETKSLETPPYLLSS
VKS-----QTLVSGTSPEMNAVKKQEIPWSEL-----------TPD--------------
---------RHTVQTIQTSKDLTS-----EMSKQSVLASK----HHMEVVEDTHVSEPHS
SASSNYA-QFI-----KNASAINAGRMVPHREISKEPEDTYVKGEDF-------TVTSKP
AGL---SEDQKSAFNIISEGCEILNIHASAFISSVDQEESEQMQDKLEYLEEKASFRTI-
SLHDSSEAVPCHKTLK-SEL---EDSDQ-VISLQE-NKRKESL---------NTKREVPT
DSETDDFTFNQPTA----PS-DEDYFEKYTLIDYNISPDPEKQKAPWKLN-VEVELPKEV
TQDTVSFPERSEEGALEHEYDLV-KLDESFYGMEKDYSKS-SHPETQKPLGIQQSAD--R
DAS-KNINRDVDLKSPGMPLFGAEEGVLSPTQIFPTTTKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHGTSVSQKD
QGQGLEEKGVGKDDSYKLIAA--EGEIW---GRFGTVLGEKSLEEEQ-KATYREEESVCH
VETLDIEA-MQGKAPITEEVTVVTQK-VSYAVPFEDTHHVLERADET-------------
-------NSQN------NE------AA---------SASPEVNLNVPVQVSFPEE-EFAS
GVTCVQETLQEESKIMVPSEQSED--RLRSSPVQDEYEFAESLNYEMVAQ-DTLSEE-LY
SESTPEDVL-SQGKESFEHVS--ENEFVSEVEQSMSVEQKELGGEKAEQEQLLSE-SATE
KEQKEPKKSQIDTYCYTCRNPISAVDQMFGMHKDHEVATLDTAINAVKVQLAEFLDNLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKKLEEQNEEMMKKVLAQYDEKAQSFEEVKKRKM
EFLHDQMVRFLQSMDTAKDTLESIVREAEELDE--TVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NDLVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNMATIRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGASEQSEAAL
ISTR--GTRFLLLRETAHPALQISSDGTVISFTERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSHSAVQ-AGTLGHGETSWYMHCSGPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLLFINAESGQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSTRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MGTRRRPGSW
T-PRRSRRARRARRPRSRSRSRTPGSVEPLL--R----------------APSAAVGEG-
-RLSDQDEEGKTKKTCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
LEGSTL-NSPPGNVSFIVDEVKKVRKRKPK--SKHGSPL--LRRKGNKKRNSFESQ-DVP
ANRKSNPLISESQVLNTQKEKSST---GIYDKTEK----KKSTSSTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKD--ASISLEPDL
GNRDSTVVSKTGKL-----VAQSIEED----------------KVKELASPWRDALSKG-
----------SKSPT---------SLFSHEDR-EKMYIDSPLRAA--SATK---------
-----------------PTPSSYTNDDIAE---QEPQVSTPKSV----------PQPPAD
EAKPREMEPASLTVD-VSAAAF--LEPAKEKLEADLQETITEDHDSSVSPPSVDEIKKED
MSSADHSIS------LEAEKGSLETGSPAPAASIQED----FGPEREELDLTALEQAEPV
SEQLTPP-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------HLSV-------------KGDKEENVPELSISLSEPLVLEEPE
KEEIETSLRVAATPEPEDSNLVE-EEIIELDYPESPSVSEEPFPPRL-APEVEQ------
------------------------------------------------------------
---------------KEEETILPLLTTP-------------TPEHV-LSEEERE----EN
ESVSTDSAFVSEYSVP----------QDLSYELEK----QDI------------------
----------------EPVSLSHVKAVSEHAVLS---------------EEENDEFEPYS
PASVSTSEH--------------------------------------SLSPSKMEQIPEC
QSPLFSTVTLEHVVLSGEEASES-----GRYTPDSTSAS--------------EYSLPSQ
ATKESL--KETTDHKSPLKS--KGVPEPMISSEEGKDDTGPCSP---EVASVPEGSLPPD
TTKGTSEWLAPPLSA-ATSEHMVLSENEN-LGNEPFTPDSTLTSQYAVLPNVTQESPKTV
VDDVSLLESKGVSEHKILSEEE--------------------------------------
------------------------------------------------------------
---------KEDTGPYSPEVASAPEHALPPDTTEGTSEWLAPPLSAA-TSEHMVLSEN-E
NLGNEPFTPDSTLTSQYAVLPNVTQESP-KTVVDDVSLLESKGVSEHKILSEE-EKEDTG
LYSPEV-ASVPEHP-LPP--------DTIKGISECQVPPL-----STIPSEHVALSEEET
V-----EVDRYTPSSI---------STS-EFSVPPFATPEPQEEPIIHISHRNLK-----
------------------------------------------------------------
----GASSPVNFSEEE--QEDIGPFSPDSAFVSEFSFPSYAAQETEKREFECDSPICLTS
PSEHTLLSDEDTEEAELFSPDSAS--QASIPPYRIPETNKKEIEPGSLLTAMAASGYSSF
AEAHEEEI-ASTST---TPV-PEHLS--SSQQQRAEPPPSTST--PEDLSQLPSTD--EA
EKAEIKSDVQITSTSVSEHLILAQK-------TRTRTYL-EPESEDLNPPCLT---S---
------------DSEKGEIQPSS-SLAATP----V--QSSIVKEETKPVLPTSQCLVSPD
IV-------------------HAVKKEQEPKASLTPE---------SADEQM--------
-ALLKVK--------------NGEEIVPNSQEAIAHVL------RD---QEMVPQPPN--
--VPESGMKYSVLPDL-VD-----------------------------------------
-------------------EPKKDVKPDLAPTVTS--ELEQRMLSENEP---EVIKPYSL
LKETSFSGP----------------------------EILS----------VVKTEVKHV
SKITGTP----GVLQSASPGVEKEVE---------------------------------H
EPPVP------E--FSALS--EEIRQEIEPSPSVT-TS-VTK---------HDS------
------------------------------------------------------------
---------------------------------------SLPELAKEEIPTDL-------
-----------------------------------SLTTPVEH-SVLTKVGK-------S
ELGSGLP----------------PL--VSSTDEHSLLKEEENVAI---------------
---KA-SS-PPETAVSQHPTW--SERE-----KEIK-------FDVPPSISSISEHSVLS
KIETE-VTPELPITKALPSQ------------------QSDVSKEAMVE------NKQDL
SLSPVLDSEHLDLSQMKMSTSAAEVSGPEHVLLLNRGGEIKKTETELPSSQNVSPAPKHI
IPKGKNEEMAGSSPEFERLASEDLPPALPTLRDDKNKQVMETSSVGQGEFPSEKQGLAPA
E-----LFLEPEKKDKPHRISELPN---AGSEFTSGLGRQSGSIDTEQIKAPVTETGDSV
LEKGPAELRSR-EGKEENREPHV--STPV-PEISEISSCLREEPQIQEIKSFSP---SLG
SKEALTSLLEGDSPEELQPHMLSLKGLSEELTHSADFKKGEKQEISSLLPTGNLKAQVTG
DTIIRLKEETDQPN--SFHAPQSITEPSKIASSDLLVEQEKPEE----GLHSDQTVKLPD
VS-----RSFADKEDLGTKPFLVMKENLPLEESRSFTTTEPTYVKETHLKEALISPKD-E
NWMLKKPE-DLAGYHEERVPGSVQLGSFGT--SDLMIGELKPTL----------------
-SEKDHTMEIGKQVLPCSAEESHLPLQEQVSTLDTARGHAETLSTKTYSSEEINL-TPKP
QSLVPAGKVERNEAEGKQTLPLMEDENLVLRKANREYSRPCIE-DSQEEIKTPSEIILR-
EQVSGPSVDQVKSETLPSVVKAAHFLAEEVEPAL-GN---EKEAQ-QPVCPSRGEKPLEE
SKVILSKVVDDANE-----RGKPASEV-KIPTQTKH-LPSTQE-NEEPQLPESPEVVQKL
PEVQKAV-EPGLSEEKGKKGISSFTSWMSSLFFRSSTPDNKVAKK-EAL-EAKPSPSVEK
AETVI-ESRGPA---P-ADIQATEKPADHIIPEPKPKIADKPRDTLVKSGEGQDFK-EKP
TSLSNADVLQQPKSN---LEGSSEGYGKKEVLDYTEETDLNSVLLSADGEGHLRIQSYSP
KGEKSIVEEAKNVVPLHVTDSKRLQKP------------EIAPPSKWNISILKEEPR--S
DQ-----------------------------------------------------KEKSL
FSFDAVDKVPQKPKSPSSSFAIKDT------------TEESEKLESIILPIEESKGNLIH
LDEDRLEKEMPKHTSLKFSEEEIKFRSVSPTEEEDNLRMRSFSSAEKQVLAEKQEPV-AP
LQLRGDNEIGKAQITHGLSPVTLKEAKPAAVWQQVCHN-EDHKERYKIIEEEK-------
E---EKEKE---KFSEGKQQQEIQPCSENIARHMPVELEI------------------S-
--FSHTLG-E-----TQPFSLEKTTAITEKSET---------------------------
-----LISEAYPEIRETKAVSVQPHPLEEHKV-VEKSETLLP--------LDLPYRDEID
DRSSPKEGNLVVEK--S-------------------------------------------
---------------------------------------------NEDVVSHSEEKGQ-V
TVSGPPKYAPVDIPKESMREG----------SPSKESERILDRPFGETKNLETP-YLLSS
VKP-----QTHVSEGSPEISTMKKQEISWSEL-----------TPD--------------
---------SHEDHTVQTSRDATS-----EMSEQSVLISK----HHLEAVEDAHS-----
LASSNYA-QFI-----INASTVRADEVV-----SKEPEGTYVKDEEF-------T-TSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQEKLEYLEEKPLFKPL-
SLYDKSEALACHKTLQ-DKI---EDADKKVTPLKE-SKQEETH---------RTEEELSP
DSETGDLAFNPPAI----PS-EEDYFEKYTLIDYNISPDPEKQRAPWKLN-VEAELSKEA
PEETVSFPEHSEESALEHEYDLV-KLDERFYGPEKDYNKL-SDPETQKVLVIQKSAD--R
DAP-KSTNRDVDSKSPGMPLFDAEEGVLSRTQIFPTTAKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTEKD
QGQGLDEKPVGKNDSYEPITA--EGEIW---GRFVTVSEEESLEEKQ-KAAYREGESLGH
VETLDTVA-MQRKAPITEEVRVVTQR-ISYAVPFEDTHHVLERVDEM-------------
-------SSQA------IE------AA---------NANPDVSLNVPVQVSFPEE-EFSP
GTTCVQETLQEEPPIMVSPEPSAD--RLRGSPVQDEYEFAESLNYEVVTQ-DTLSEE-LY
SESTPEDVL-SQGKESFEHVS--ENEFVSEVEQSMSAEQKDLGREMTQQTQLALE-VVAE
EE---PKRSQIDTYCYTCKCPISAVDKMFGTHKDHEVSTLDTAISAVKVQLAEFLEDLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKRKKM
EFLHDQMVHFLQSMDTAKDTLETIVREAEELDE--TVFLT----SFE--------EINER
LLSAMESTASLERIPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMSKEDVIDSFQVYCMEEPQDDQEV--NDLVEEYRVTVKESYCVFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPAN--LEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSSGTVISFAERRRLTEIPSVLGEELPACGRHYWETT
VTDCPAYRLGICSSSAVQ-AGTLGQGESSWYMHCSEPQR---YTFFYSGIVSD---VHVT
EHPARVGILLDYTTQRLLFLNAETGQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------S-
-RLTDQNEEDKTKQECIISDPSFSMVTVQREDSGITWETSSSRSSTPWASESSLTSDMYS
LEGSTL-SSPPGNISFILDEGKKVRKRTHKSSSKHGSPA--LRRKGGKKRHSLEGQADVP
ANTKDNALISDGKLPGTEQEKSSI---GTYDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEEIIPLQFYGTLPKGYVIKEINYRKGKD--ASITLEPDL
GNQDSSISSKANKS-----MTQIIESN----------------KEKQLSPPWREKMSRE-
----------SRPMP---------SFLRDVEQPKDIDSYSPLNAAAASGPK---------
-----------------HTVPSYSSNEAVE---SQSLPSSLSTL-------------PVE
EAPMRKIQM--DSPD-AAAFELASPKMVKEELTPETQA-EASSPLLSTSPSFVDEVGEEN
LTSS------------KAEEEALELDSQVTAVSAPEP----FGTNVENLGQSS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LEKEELV--------------
------------------SPTG-------------EEETEETEPESSVSFSKPSAVGEI-
KEEGDGSLPVTSRPELEPSYVSE-EEIIEIDYPESPSPSENAIPPHL-VHEEER------
------------------------------------------------------------
---------------EENESDLPLLATS-------------TSEHVALLEKERK----EI
GPISPDSDFASEFSGP----------SYSTHELEE----KET------------------
----------------KPVSPPDIMSTSESEILS---------------EEE---IVPYS
PGFTSVAEH--------------------------------------SMTSPTAEE----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------ESIEYKPPIH-----SAATSGPAIFSEEET
L-----ESERYTPDST---------SAS-EYSIPPYAAQELQKEDTSQRSPLSPL-----
------------------------------------------------------------
----AATDHMIMSEEE--KDDIGPYSPDSAFVSEYSVSPRTVQESEKEEFEQDYPIHSTS
PSEHTLTE-EEHDETEPFSPDSAS--DISIPAYKTPEPEK-ETEPGSLLTSMSVSEYSIF
SEAEKEEI-EPKTQASTMSA-PDHPT--LSDRQKVQHSSIEPR--SENLNLPSSTA--GV
EKEEVKPDAQGAATSVSEYLISSQK-------QKIEGPSQVRESEHSMPPSST-------
--------A---GVEKEEVKPD-AQGVATSV-SEYLISSQKQKIEGPSQVLESEHSMPPS
ST-------------------AGVEKEEVKPDAQGVAT--------SVSEYLISSQKQKI
EGPSQVRESEHSMPPSSTAGVEKEEVKPDAQGVATSVSEYLISSQK---QKIEGP-SQ--
--VLESE--HSMPPSSTAG-----------------------------------------
-------------------VEKEEVKPDAQGVATS--VS-EYLISSQK------------
---QKIEGP----------------------------SQVATSVSE-YLISSQKQKIEGP
SQVLESEH---SMPPSSTAGVEKEEV---KPDAQ--GVATSVSEYLISSQKQ-----KIE
GPSQVLESEHSMPPSSTAD--EGKKEEISPHLSVPVAP-VFK--------KADS------
----------------SEKEKIGPVLPETS---------------------------VSR
PQ-------ESITSESTQKTKKELGPKPAHAQKGASEHLAFSKASKEEIMLNSQVVPSEY
P-------------VS----SQHKEMESHSPRTPEYVTEPSVA-SVLSKERK-------G
EVDSLSP----------------P-------TEHLVLNKEEKEVG---------------
---ES-GTSPIEKAASKPPIR--SEVEVDKVDKEVEVDKEEKNFQASPHDRYSTEHSISS
KERQEEEEPRSPVP--------------------------EHSVLSKVG------NDQGL
PPLTVPATEHLTLSEKQTSESSPLASVTRSSVPPHMTIEGEKEDTKLPLLETTISASEHR
VSSQAKGETKYPSHELETLVTEEVSMKSVTPAGERSRQEPATLMPEKGHLLTERPDGPSL
R-----HTLEPEKT----------------------------------------------
------------------------------------------------------------
---------------IMPPYALELSGSVSQNLVSECERENADQEKSLSPEIGSSGLERVK
SEA--KTREEGKQEHKDLSLSLSGPKPSKMKFSDLSEGLAKQKT----TRYPDEVVNLPD
LS-----TQDI------AKSHSFEEAHLPLEESKSVVTMECRDVKEAK--ESLPLPKE-H
IWVPGEPSQELAGPKEERLLESGQPYSSAT--DGRLLGELTSAP----------------
-KDS--------------------------------------------------------
------------------------------------------------------------
------------------------------ETAL-GD---EKEDLGRTPHSFTEKKLLQE
SKADTSKVSKYADEAQQPETKKPLPEA-RISSQEKSKLSLIQP-KEITAPLDSPEIINKV
PEQADTAATGALTESKAKKGVSSFKSWMASLFFGASTPENDVDEK-EAP-ETQPSPAADT
AVLGD-EAKTTVPAAP-DDLNEAEEPASSPLSMSGLLIEKEHPAILIKASEERELK-ETP
LSLPNQVGKEPSKLTPLREEHKTPGYRKEEMQS-----------LSNRGMEMPSKEPASI
KGKKLVSEEAESGAPIHFTGDNKVQKA------------EIYSPSVTSQLIEKSKSVLTY
LD-----------------------------------------------------EQQKL
SSPEKVDQVSWPPKPATSEFADESF------------KKDSAKLEPRTLTMEEPQGRLIK
ADGDRPEKEMTKTMSSTFYDDESKLRTVSSTDEENVPEQKPYCITEKDVLAEKPEMV-AP
LILRDANKISMAEEPRLHKAE-----HAKESVFQFCENKEDEGMLSKIPVGVSVGSEPPK
STAPATNENQIFSAERGMWE-DSKPHPILG----------------------------A-
--REVSVD-E-----SQPLSFAKADFFKDS------------------------------
---------------------------------------------------QIASVGPTE
GHKEKSCQSPL-------------------------------------------------
----LGKEKVISERSEA---ITVSSEEEVEQ----------------HLPGETNQRTQ--
-------------TYLAGKAS----------FASEESGFTFGISYDETKNLKNQTCSLAK
AKSVTGESQMALSVAHPEIKGTKISVISESSPEVKRSQIPEVSTPE--------------
---------LTGTGQAQQEKDRAP-----GSPILPTFVSKQISDSQIKPVEHLRVDKLYP
SAVHDSD-QRT-----FDKPSTKSEEI--FSTVAEEPENVFVKNGAF----AAPVVTSKP
PGL---TEDQKNAFSIISEGCEILNIHAPAFISSVDEEECEQMKDKLEYLEEKTSKSIQ-
LFHDAREETTNQETVR-NKS-HVGHLEEDVS-LVKGQMQEKPL---------PAEENIST
DS---DVAFSSHMT----PS-DVDYFEKYTLIDYNISPEPQKRESLPKQD-IEGEPQKKV
SEETVSFLESSEDRTLECEFELV-KLDESFYGMEKGDEQV-PHTQSQPSLLALQSAT--S
ETP-RDIAREGESKSPGMPLFNAEEGVLSRTQLFPTEVKAINPELLEEPPALAFFYKDLY
EEAVGDKKKEGEATSDGESLNSEASFPSRHSDAEEEAGMYFEKYILKDDILHEASGYQKD
QDQPLEEIPVGKDDSCQLIAA--EGEVW---GRFGTISGEMGMKEEQ-KAMLNEGEFRNS
MENSKDKE-LQGKTPITEEVQLASQK-ISYAVPFQDAHHILERVDES-------------
-------DGQG------IE------EE---------NASAEASQHIPVEVSYPEE-EFVS
GATPVPESLQVEPQELVAPEMREA--RPCSSPVQDEYEFAELMNYEVVTQADLLSDD-LL
SESTPEDVL-SQGKESFELVG-ENDEFAKDAEQRRSAPQKDLGSEVVEPEQLLAE-M--E
DAQKEAKKSQIDTYCYTCKCPISAIDKIFGAHKDHEVAALDTAISVVKIQLGEFLENLKE
KSLKIEAFVTEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EYLHEQMVNFLQSMDTAKETLETIVKEAEELDE--AVLLT----SFN--------EINDR
LLSAMESTASLENIPTAFSLFEHYDDSSTRSDQ-TLKQVAVPQPPILEPQEPNSATSTT-
-ITVYWSVRKEDVIESFQVYCMEDPQEDSEA--NELVEEYRLTVKESYCLFEDLEPGRCY
QVWVMA----VNFTGCSLPSERATFRTAPSTPIIKAEDCTVCWNTATIRWSSAN--PGAS
DAYTLEYCRQHSPEG-EGLRSYSGIKGFQLKVNLQPNDNYFFYAKAVNAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSDGTVIRFTERRRLTETPSVLGEQLPACGQHYWETT
VTECPAYRLGICSSSDMQ-ASALGQGDTSWYMHCSEPQR---YKFFSNGTVSN---VHVT
EHPVRVGILLDYSNQRLLFINAESGQLLFTIRHRFAGAVHPAFALEKPGQFTLHLGKEPP
DFLRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--SSDQDEEGKTKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
LAGSTV-NSPPGNVFFIMDEVKKTRKRAHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKRDNRLISESQVLNAGKEKSYT---SIYDKTRK----KKTASNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDM
GSSDSNIVSKTGKL-----VAQSIEDD----------------TAKELAPPCRVALYKG-
----------AKSLT---------SVFSHEDQ-KQAHVDSPLSAK--SASE---------
-----------------HTVSSYSSNDTAE---REAQPRPPQS------------QQPDL
EAKIQETEPFSLTPT-IAATV---LGIAQAESELASQEVVTSGDDYLASASLT--QVKED
MCSADHFVS------LEA-------ESPALEVSVQEG----FGLDKEQLDMTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LEKEEPVSK------------
--QLSPP-----------HPSV-------------SEEKGENVPEPSISLPEPSVLEEPG
KEGVETSLPIVAAPEPEDSNLVE-DEIIELDYPESPPASEQPFPPLL-APEVEH------
------------------------------------------------------------
---------------KEEVPVLPLLI-S-------------TPEHIASSEEERE----EN
ESVSTDSAFVSEYSVP----------QDLNRELKK----QEV------------------
----------------EPVSPPNADAISDHSVLS---------------E-GNEELEAYS
PATASVSEH--------------------------------------SLSPPMAGKASEY
QSPLFSMVTSEHVVLSGDDVSDS-----GHHTPDFIFAS--------------EHSVPAQ
AMQELL--KKATDCESPLSS--KGASEHRLPSEEEKEVSGPCSP---ATAFVSAHSLPPS
TAEKTSGHQSLLPSP-AASEHMVLLEGED-LGSEHFMPDSKLTPKQAASPNALQESQKKK
IG-VSLLKPKDVSEHTILSEEE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KENAG
SRSPVV-APASEHS-FPP--------PPTEKAFECQAPPL-----SAIASEPVLSSEEET
V-----ELERYTPSST---------SAS-EFSLPPFATPESQEEDIVHRFHLNLK-----
------------------------------------------------------------
----GASSPMDLPEED--QEDIGPFSPDSAFVSEFSFPPYAKQEGEKREFEYDSPICLTS
PSDHTILSDEEIEEAGLFSPDSAS--QVSIPPFRLLETEQNESESDSLLTARSASGYSCF
LEVGKEEM-GSTVA---TPV-PEHFN--SSQKQKAEPFLLMSA--FEDLSLPPSTN--TL
GTAEIKPDVQTTSTSVSEYLILAQK-------QKTQASL-EPESEDLVPPYLT-------
--------S---ELRKGEMKAS-LAAATTPA--SFLAQSSMVKEETKPAP---QHSVSPD
SV-------------------HAIKKEQEPKESLTMK---------AADEQV--------
-TLPTVE---------------QEESVLDFHEVITHAS------QD---KKLEPQHPS--
--VPGSGMKHSVLPHL-VD-----------------------------------------
-------------------EPKKSVKLNAAPDMTS--EPGQRMLLKNEP---EVIQPYSP
LKETSLSEP----------------------------EGLS----------AVKIEMKHD
SEIISAP----RVSLSVSSGVEKQVE---------------------------------H
GSPA--------PAFSALS--EELKKELEPSSSTTMPS-VAK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKLVREEIPTDS-------
-----------------------------------SFATPVDC-SDLTKVGK-------G
ELGSGLS----------------PL--VTSADEHSVL-REEEKVA---------------
---IN-SVSPTEMSSSKHLAW--SEAE-----KEVK-------RDSPPSISSISAHSILS
KVETEDVKFGLPITKTS-SQ------------------LSDVSEEEKVD------DKQSL
SYSTVVDSEYLVLSQKKNLISA---SGPEHGMLYNLSGEIKKEETELPSSQNVSPLSKHK
VSKGRNEEIASSFPELEDLLSEELTPTFLLPSDDKSKPSMEISSTAQGDFLSEKQDLILT
E-----ISL-----DKPHQPPEFLS---AGSGFASVLGRQSESLSPKQVKCSITETEDSI
LEKGLAEFRSRE-GKEENRELHL--FTTV-PAMSEVSSRLEEEPQNEKIKPFSPQVVSLG
PKEAPASLVEGDKPEELQPYTFSLKGLSE-LNQSAIFKSGGDQIIDLLPSSGKLQAQVRG
GVVTKLNEETGHSD--SSHVPQSITEPSEVTSSDLFVEQKKIEK----APHSDQTVKSPE
VS-----T-FVDKQDLDVKHFLFMKEDLPLEQSKSFMTTLPVDIKETKMGESFISPKD-E
NRMLEKPECV-ASEHEERTLRSVQLEFTDS--SDTKTGQLRTAL----------------
-SDEDHMHEVREQVFPHPAVEALLSLREPLSTLDTSSGNVEIWPSNTYSSEEVKL-AQEP
SSLVLVGNVERNIAEGKQIHSSMGSEGLISEKANTKFSIPCKE-DSQEEIKLPPERSFQ-
KPVSGLSMEQMELETIPSSVKTAHFLIEDTEPAL-GN---EKEIQ-RRTLPLLREKLSEE
SKMVQSKVVDDAYE-----GGKPASEV-KIPTQSKP-LSSIQA-NKEPQSPESPEMMQKL
PEQPKVA-KSGLPEEKEKKGISSFKSWMSSWFFGSSTPDNKVAE--KDL-ETQPSPSVEK
AVTVI-RPKDTI---P-ADFDAAERPLDHSLLEINLKTADESRGTLIKSGEGQDFK-EKL
TVLSKVEVLQQSKSN---SEVSREDYGKKEIPDYSDEMNICTVVTSTCGKEHLGIQPYSP
IGEKLVMEEAKNIAPLHVNDSKRVQKP------------EISPPSKWGISILKEKPG--S
NQ-----------------------------------------------------EEKSF
LSLDVVDKMPPQPKSASYNLTSENI------------MKESEKSESIILPVKESKSSLID
LGEDRLKKEILKPPSLIISEEEFKLGSVSPTEEKGYLDTRSYALAEKKVLAEKQDTV-AP
LELRDDHEIGKSQITHESRPTELEESKAAVMLQQLYQN-EDHSERSKIIVNSK----EEK
E-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------DIAIIKESMKQG----------SPAKESERTLDSPFDETKSLEMPSYLLSS
VKP-----QTHASGTSPEINTAKKQERSWSEL-----------TPD--------------
---------RPTVHTIHVSKNHMT-----DVPKQSVLVSK----HRLEAVEETHVNEPLS
PARSNYA-QFI-----MNASAINADKMVSTKEVSEKPEDMHAKDKEF-------AVTSKP
AGL---LEDQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQDKLDYLEEKASFKTI-
PLHDDSEEVVFHKLIK-SNL---EDSGETVVSLKE-NKQKETH---------KTKEDIST
DSETGDLGFIQPTL----PS-EEDYFEKYTLIDYNISPNPEKQTTPQKLN-VEEKPSKKV
TEETLSFPENSGEHVLEHEYDLV-KLDESFYGLERDHSKS-SPPQTQKSLVIPKSVE--R
NAS-KCLSRDVDSKSPGMPLFDTEEGVLSRPQIFPTTAKAINPELLEEPPALAFLYKDLY
AEAVGEK--EGETASEGDGVNSEASFPRRNSDTDDGTGIYFEKYILKDDILQDTSVTQKD
QGQGLEEKWVTKDDSCQPIVA--EGEVV---GKFGTILGEKSLE-KQ-KAVCREGESVGH
VETPSNTV-MQRKAPITEEVSVVTQQ-ISYAVPFQDTHPVLECVDEA-------------
-------SSQS------DE------AG---------HTSPEVNLNVPVQVSFPEE-ESAS
GATYVQET-LQEPKIPVPPEPREE--WLRNSPVQDEYEFAESLNYEVVTQ-DTLSEE-LY
SESTAEDAL-SQRKESLGHIS--ENEFVSEVGQSTSAEQKELGRERQEKDQL-SE-LVTE
KAQKEPKKSQVDTYCHTCKSPISAIDKAFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKRKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTSSLEKMPAAFSLFEHYDDSLVRSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRVTVKETYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERALFRTAPSTPVIHAEDCTVCWNTATIRWQPAT--LEAT
ETYTLEYCRQHSPEG-EGL-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MATWYGH-----
--ADGDPTAVW-------EVEDAM---EEAAEESE----AEGEETAAESGSESEPEPDT-
-RLSDQDEEDKTRQECIMSDPAFSMVTVQREDSGITWETNSSRSSTPWTSEGSQTSGVCS
LEGSSV-NSPPGSVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGSRKRNSFESQ-DVP
ANKKDKSFISESQALNIEKENSSP---GIYDKTRK----KKTASNTPLITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
ENHDSNIVSKTSKL-----VTQSTEDD----------------KLRELGPPWRGVLSKG-
----------SKSLS---------SLFGHENQ-KKIDVESSLKAT--SAAE---------
-----------------SIASHYLSNNAAE---QEVLLRPPQSV------------QPGD
EAKAHEIKASSLLLK-ASQTVF--QETAKEESEAEVERAITLEMDSSVSSALLDEAMKEV
MDFTDCTMS------LEAEKDLSETVSPGLSPSTEEG----LEPGKEELELTSLERMEPA
SECMAPT-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------HSSV-------------KGEKEEPRPEPPISLPEPLMFQEPE
KEELEASPPIAAIPEPEGSNLE--EEIIKLDYPESPLVSKQPFPPQL-SPEMWE------
------------------------------------------------------------
---------------KEE-PSPPLLTTV-------------ASDHVTLSE-ERE----EI
ESVSTDSAFLSEHSVP----------QDLNHEREK----QEV------------------
----------------DPVSPSSAKAISECAVFS---------------EEENEEFEPCS
PAVASVSKC--------------------------------------SLWPPTPEKPSEG
LSQLFSAFPSENMVLSGDEASES-----GHYIPDSTS-S--------------EYSVPSH
EAQESL--KKTIDHKSPLKS--KDVSEPVILSEE--KDPESQDP---AVASVSERSLSPP
LIGKTPESQRPLPSA-AILQHMVLSEKED-LEGEHFTLNSK-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------LTSKSEVPLNATQES--QKIIDEVPQFKLKDIFQHTILSET-ETEDVG
SCSPDV-VPAPECS-LPP--------HTTEMISEYQAPPH-----AGTLSEHVVLSEEET
I-----ETERYSPSST---------STS-EFSVPPYAMPESQEEEIVQRSPLHLK-----
------------------------------------------------------------
----GASSPMNLSEQ----EDIGPFSPDSAFVSEFSFSPYSTQETEKREFECGSPVCLTS
PSEHPVLSDEDTEDGGLFSPDSAS--QVSVPPYRIPETEINESEPDSLLPARSVSGFSYF
SEADEEET-GSTAA---TPI-PEYFD--SSEKQKAEPFPIMST--PEASSLPSSVD--EA
DNAETRLDVQTFSTSVSEYLILAQQ-------QKTEASL-EPEPEDLIPPYLT---N---
------------RTEQEEIKAKSS-AATTH--AASNVQSSLAKEETKPISPASQYSVLLD
SV-------------------YATKKEQEPKASLILK---------AADEQM--------
-ALSEVR---------------KEETVPDSQEATAHVS------QD---QKLEPQTPN--
--VPGSGIKNSVLPEL-VS-----------------------------------------
-------------------EPKKDVNLNLAPTVPS--ELEQSTLSKNEP---KVVKAYSP
PKERSISGP----------------------------EVLS----------AVKTEVEHV
SKIT-------RGLHSTSSGVEKEVE---------------------------------H
GPPA--------PTFSALS--EEIKKEMEPSSSTT-TP-VTK---------CDS------
------------------------------------------------------------
---------------------------------------ILTKLVKD-IPMDS------F
PAKL----------------------LKDIP-INSSPATPVEEHPGPTKAGE-------G
ELGSDFP----------------VL--LKPVDEHSILIEEEKVVI---------------
---TS-ASSSIKASLSKGLAP--SEVE-----EETK-------MDSPPSVCSTSDHSILS
KVDTEEVKPGLPVDKVSSPQ------------------HSAVSEGAKGE------DKQGL
SFSVALDSTHLVSSQDT----ASEVSRPEPVLSLSLESGIEKEETRLVLSHTVSPAPKHI
VPGGKNEDMTSSSPKFENLVSEDLVPTLLTLGDGKNKQAGDITSPVHGDFLSGKQDLAMA
E-----LPLESEKKDKLHQLSKLP-------EFTGGLGRQSGPIDTEPVTCLITDTESSV
LEKGLVELRSREKEKEENRELCV--SAAE-------------------------------
------------------------------------------------------------
--------------------------PSKIASFDLSAEQKKPEK----LLYSDQAVNLSD
VS-----SSFEDKPDLNIKQLPFMKENLPWEQSQSFITTEAEQLKSSS------------
-------------------------------RSDPQIGQLQSAP----------------
-SNEDHTYEIGKQVLSQAVKESHLPLQTPASTPDASGSHTETLSTETYSFEEIKL-VQEP
KPLVPIGNLERNTEK-GQIHSFMESESFIPEKANIDFSSLSKE-SIWEEVKLPPETPTQ-
KPVSGPSAGQMKLEITSFPVKASHFLVEAVEPAL-GS---EKEAR-RSIPPLLEEKPREE
SKMVLTKIIDEATE-----GRKPVLEV-KIPIQTKP-IPSIQA-NEEPQPPETPEVTQQL
HEKPKMT-EQRLPEEKGKKGLSSFKSWMSSLLFGSSTSDDKVPEK-EEL-STQPSHSVEK
AVTMI-EPKGKS---P-ADFNATKKPGDHSLPE---------------------------
--------------------VSSEDYGKNKTPDSSEKMSIDLI-TSADSEEHFGVQPD--
--KKLVMEETKN-VPSHVTESKRYQKP------------AIAPLSNWNISILKEELS--G
DQ-----------------------------------------------------KEK-S
FSFDVVDKMSQQLKSDSFTFTSKNI------------MKESEKPEPIILPVEESKSSLID
FGEDRLKKEIPKPTSLKHSEEEVKLGPVSLTEDKDNLETRSYTLAEKNDLADKQEVV-PP
LELRENKKVVKSQMTHEYRLVELEESKVAARLEHIYPN-EEHKERAKIIVCSE-------
EENREEKEKQSQVFLEGKKQQENQPDSLNVARSMPEEPVI------------------S-
--SLHSLG-E-----IQPFLSIKTPSITEKPES---------------------------
-----VLSEAHLEIKERQVVESQPHPLEESKSFVKKTKTLCP--------VDLPYRDEID
KHPFPQEENMVLEK--S-------------------------------------------
---------------------------------------------SRYLAGDREEKGQ-L
TLSQLSTGGSVATTKESTSRG----------SPSLIPGSTVDHPSDDTKSLEMPLYLLSS
VKP-----QTLVPEVCPEVNIAKKQEIPWTEL-----------TPG--------------
---------HPTGQTIQTSEDHSS-----EMLKQSVLISK----HPLENVEDAHINELSS
AAGSNYA-QFI-----ISASKSKADEMTSAKEMFKEPEYAHAKKVES-------TVTGKP
TDL---SQDQKSAFSIISEGCEILNIHAPAFIPSVDEEESEQMKDTLEYLEDKTSFKTI-
SLHDDSEAVVCHKMLQ-SKL---EDSEGKVTSLKN--EGKEAH---------VTKEKIAM
DSDTGDLAFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPWKLT-MKEEISKEA
TEETLTFPESSQGSVLEQEYDLV-KLDESFYGLEKDHSKL-SQPEMQKSLVTQKSAD--R
NAS-KSINRDVDSRSLGMPLFDLEEGVLSRTQIFPNTVKAVNPELLEEPPALPFLYKDLY
EEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGMYFEKYTLRDDILHDTSVTQKD
QGQGLEEKPVGKSDSYQLIAA--EGEIW---RKSGIVLWEKSLE-EQ-KVVYGEGEAIGH
VETSNDTA-EQKKAPITEEVRVVTQN-ISYAVPFQDSRHVLESVAEV-------------
-------SSQD------NE------AG---------NISQEVSQNVPTQVSFPEE-EFVS
GATNIPETPQEEPKILVPPEPSEE--RLRNSPVQDEYEFAESLNYEVVSQ-DTLSDE-VY
SESAPEVVL-PQGKESVEHIR--KCELLTEVEQNTSTDQNKLARGKTEQDQLSSE-LVTE
KAQKEPKKSQIDTYCYTCKSPISTMDKVFGTHKDHEVSTLDTAICAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCTKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLEAIVREAEELDE--TVFLM----SFE--------EINDR
LLSAMASTASLEHMPAAFSLFEHYDDTSAGSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVFRAEDCTVCWNVATIRWRPVN--LETT
ESYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSDAAL
ISTR--GTRFLLLRETAHPALQISSDGTVINFTERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAVG-ARALGQGETSWYMHCSEPQR---YMFFYSGIVSD---VHVT
ERPARVGILLDYANQRLLFINAESGQLLFIVRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDGN-----
--RTTEGLLGS-------DGDEEAARELDTEEEES----SEGEEE---DTAESEEEPEA-
-RLSDQDEEGKTKQECIISDPSFSMVAVQREDSGITWETNSSRSSTPWASEESQTSGVCS
LEGSTL-NSPPGNVSFIVDEVKKARKRNHK--SKHGSPS--LRRKGSKKRNSLESQ-DLP
AHKNDSPLISESQALTTEKEKSSA---GIYDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNRDSNVVLKRGKS-----VAQSIEDD----------------KGKELAPPWRGALSKG-
----------SKSFT---------SLFSHEEQ-KKSYVDSPLNAT--PHTK---------
-----------------YTDSSYARNNTAE----QGQLRPQQSV----------PQQSED
EVETHETEPTSLPS----ATAF--LETAKEELKPDSQDFESSEIDSSSSLAFTDEGKKRD
TLSADHSVA------LGAEEDSL--GTPGLVTSTEEV----FAPGEEELISS--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------DRAEPASE------------
--HWTPP-----------HPSA-------------QGEKKEHMPEPFISLT----LQEPG
KDEVGESLPTAATTELEDSDLA--EEIIELDYPESPLVSEKPFPSRV-SPEVEH------
------------------------------------------------------------
---------------KGEKPPLPLETTP-------------VPDHVTWSEEERE----EN
ESISTDSAFASEYSVV----------PPS-------------------------------
---------------------------TAEEVLL---------------EEEREELEPYS
PSLASVSER--------------------------------------SLSPSTTEKIPEC
QSPLFSAVTSE--ILSGDEALES-----GPYTPDSTSAS--------------EYLLPSH
ATPDSL--KKTIGSKSLLKP--QGSSEPIVLSGEEKEDTSPYSP---TVTSISEPYLSPP
TTETTSASQSPLPAA-PM------SDHTA-LSDEHFIPDSKLTSKP--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------THRALSEE-QNETLG
PYSPDI-ASAPECT-FLP--------HSPEMASECQASPP-----SASPTEDV-------
----------------------------------------PQEEEITQRSPLHLK-----
------------------------------------------------------------
----SASSPTNLSEQR--QEDIGPFSPDSAFASEFSFSPY-----------CDSPVCLTS
PSEQTILSDEDTEEMELFSPDSAS--QVSIPPYRIPDMEKNEIEPDSLLTARSASGYSYF
SEAEEGEM-GSIAA---TPV-PEQ---------ISEPFSVMSE--PEDSSLLPAVN--KA
DQEEVKSDAQTISTSVSEYLILSHQV----------------------LPSLT-------
--------S---RLEKGEIK----------------------------------FSVSPD
SV-------------------HA-KKEQEPKASLSVK---------VEEEQM--------
-TLPKVR---------------EEETVSNSQAAIAGGS------QD---QKLEPQSSN--
--IPGSGMQYSSLLPDLVD-----------------------------------------
-------------------EPKKDVKPSSAPTMTS--ELEERRLSKNEP---EVAKPSSS
PKETSISGP----------------------------EIFS----------EVKTELDVN
SSLA--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------TPGEHAGLLARLGE-------D
EVSGGLP-----------------P--TAVIDEHSVRKEE---KV---------------
---TK-SASLTETSLPKDSAW--SESE-----KEIK-------LDSSPSRSSITEHSVLS
KVEMEEIKPVMPVSKVSSSQ------------------HSDVSEESRVG------EKQGL
SFSASLSSERSVSSQ-KNLVSASEASRPEPSLSLHLS-----EETKFPSVQNVSPVPKPV
IPKSKNEETIISSPKFENLVSEALEPALLTLGDGENKQAGEESSPVQ-DFLSGKQGLAVA
E-----LPRE---HDKLVHLSEPPS---ARSELPSGLSGPSGSIDIKAIQSLVTETGGSV
LEKSRAELSYRGEGNEENRERLE--SG---------------------------------
------------------------------------------------------------
------------------------TKPSMIVSPDILVEQKKPER----ALHSAQAVTLPD
VSKV---K----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LAQGPSRERNVAEERQIHSMMGKESLILEKVNEP------------------------
--------------------------------------------AHRSTSPLPGEKTFAE
SKMVQSKVVHNSNE-----VRKPAPEI---PTRRKP-TPSIQA-PEEPQASEIPEVTQKL
PEKPKAV-EQSLPEEKGKKGISSFKSWMSSLFFGSSTSEDKVAE--KDL-ETQPSPSVEK
AVTMV-EPEGTI---P-PDAGVSRKTADLSVPEVKLKMAEECR---VKSTEGQDLK-ENS
TSLSNTEALEQPKSN---FEVYSEDYEKKEISDYSEKMGIKLA----TTEENLGIQPYAP
MGEKSVMEEAKNVIPFPVPESKSHQKP------------ASVPSSPWNVAGLKEEPS--L
DQ-----------------------------------------------------KEKSH
ISFDVVDKMPQQPKEKQSEK----------------------PAEQIILSVQESKDSLAN
LGEDRFKKEMSKSTLKH-SEEK----------------------------KDKNPEVMVS
FKYRENQGIGESQMIPDFRPTKLGESRVAVSLEHIYSK--EHKERSDIIVASE-------
-EEREGKDRQAQIFSEERK-QESQPYSLTIARSVPETPPV------------------S-
--LGHSLD-E-----TQPLSSIKTPPITEKPEG---------------------------
-----MLSEAHPEIRERMTVETQPYPLEESKVLVEKTKVFRP--------V-VPHHDEID
NHSLPQEGNLVLEK--SS------------------------------------------
----------------------------------------------KGKVMSSLKEET-F
IVSELSNDGSVAITNESIKGG----------PPSPDSEMTLDLPSNEAKKLETPPYLLSL
GKP-----QPLVSGTSPEISTMKKQEVPWSEL-----------TPD--------------
---------RPTVHTMQTFKDHPS-----EIPKQSILVSR----RHFETRGDAHINEPHS
SATSNYA-QFI-----MNTSAIIADEMTSTKEMSKEPEGTNAKEEEF-------TATSKP
VGL---SKDQKSAFSIISEGCEILNIHAPAFIPSVDQEESEQMQAELECLQEKAPFKTT-
FLHEESEEVVSHGTLK-NNL---NDSDRKG---RKESEQKATH---------KTKEERAT
NPETGDLIFTQQII----PS-EEDYFEKYTLIDYNISPDPEKQKELSKRA-R--------
---KETSPESSQQSAPEHKYDLV-KLDESFHGLEKDHKKL-PHPEPQKSLVIGESAD--V
TSS-KGTNRDVDSRSPGMPLFDAEEGVLSRAQIFPTTVKAVNPELLGEPPALAFLYKDLY
EEAIGQKKGEGKTANEGDSVNSETSLPSRHSDIDDGRGMYFEKYTLRDDILLDTSVTQKD
QGQGLEAKPVVKDDSYQLIAA--EEDIW---GKPGVI-WKKSLEEEP-RAIYREKELVGH
MEMRGEVA-TQRKVAIAEEVRVVTQK-MSYAVPFEDTCQVSEGAEEP-------------
-------STQG------NE------VG---------NASPEVNLNVPVQVSFPEEEEFAS
GATYIQETPPEGSRRLVPAEPSEE--RLRNSPVQDEYEFVESMNYEVVSQ-NILSGE-LH
SESTSKNVL-SQEKESFEPLK--KHEFAREAEQSMSAEQKELGRERTEEDQLVSA-LVTE
KAQKEPKRSQVEAYCYTCKSLISAMDKAFDTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKKEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLETIVREAEELDE--TVFLT----SFE--------EINER
LLSAMDRTASLENMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQELNSATSTT-
-IAVYWSMNKEDVVDSFQVYCMEELQDDQEF--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIHAEDCTVCWNTATIRWRPAN--PDAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSNGTVISFTERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMHCSEPQR---YTFFYSGILSD---VQVT
EHAARVGILLDYNNQRLVFINAESGQMLFIVRHRFNEGVHPAFALEKPGKCTLHLGREPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------DGDEEATRELETEEESE----GEEDET----AAESEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSR-STPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKGSPLTSASQILTTEKDKSYT---GVYDKARK----KKTPSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSTED-----------------KVKEVAPPWRGSISKG-
----------SESLT---------SMFSHEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPG-TPATVF--LRTAKEECELASPGTAASENDSSVSPSFTNEVKKED
VCSAHHSIS------LEA-------ALPDLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIDTSLPVAATPKPEDSNLVE-EEIIELDYPESPLVSEKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPENAALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----RES------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSPLFSTVTPEHMVLSGDEASES-----GRYTPDSTSAS--------------EYSVLSQ
ATKESL--KKVIDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTP---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSECFTPDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKGISEHTVLSVEG-KEDI-GPASPDS-------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VIASEYTVLSVE-GKEDIG
PSSPDS-VIASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEET
V-----ELERYTPSSM---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFASEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEVDEEDI-GSTAA---TPV-SEQFS--SSQKQKSETFPLISP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPPHLT-------
--------S---EVKKGEREAS-SSVTAIPA--SLLAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--IPGFEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSEKEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSALS--EEIKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVGH-PVLTKVGK-------G
ELGSGLP----------------PL--VTSTDEHSVL-AEEDKVA---------------
---IK-GASPNETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------YSDESEEARVE------DKQGL
SCSTVRDSEHLVSSEKKSLVSTSEVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENS-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDIALA
E-----LSLEPEKKNKPHQLLELPN---AGSEFASGLGRQSGSIGTKQAKSPVTETGDSV
LEKGPAELRSRE-GKEENRELYA--SATM-PTTSELSSLLREESQNEEIKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLVE--QKTEK----ALHSDQTIKLPD
VS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEELKL-AEEP
KSFVLAGNVERNIAEKKESHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVKTTHFLAEGVEPAL-GN---EKEAH-RSTPPFSGEKPLEE
SKMVQLKVIDDADE-----EKKPAPEV-KIPTQRKP-ISSLHS--KEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKGKKGISSFKSWMSSLFFGSSTPDRKVAEQ-EDL-ETLPSPSVEK
AVTVI-EPEGTI---P-TNFNVAEKQADHSLSEVKLKTADESRGTLVKSGEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEVNINSVVTSADGEKHLEIQPYSL
IGEKLIMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKSESIILPVEESKGSLVD
LSEDRLKKEMQNPTSLKISEEETKLRSVSPTETKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNEIGKTQITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEEKKKQEHQPYSVNVAESMIKESNI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSDA---------------------------
-----VLSDAHPEIREAKAVATQPHPLEESKVLVEKTKTFLP--------AALPCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMPDHREEKEQ-F
RESELLKGGSVAITKESMKQG----------FPTKESERTLAYPFDETKSSETPPYLLSS
VKP-----QTLVSGASPEINAMKKQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTF-----DVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTV-
PLRDDSETVACHKTLK-SRL---EDSDEKVTSLKE-SKQKETR---------HTEEKTST
DSE-TDLSFIQSTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEDKLSEEV
TEEATSFPGSSVESALEHEYDLV-KLDESFYGPEKDHDIL-SHPETQKSLGIQKSAD--R
NVS-KDVKRDVDSKSLGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKNKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVGH
VETLGNIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPDVNLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILVPPEPSEE--RLRNSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAEQKELGSEWKEENQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGIHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------DGDEEATRELETEEESE----GEEDET----AAESEEEPDS-
-RLSDQDEEGKIKQECIISDPSFSMVAVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNRKRNSFESQ-DVP
TNKKGSPLTSASQVLTTEKEKSYT---GIYDKARK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSGSNTVSKTRKL-----LAQSIEE-----------------KVKEVFPPWRGTLSKG-
----------SESLT---------LMFSHEDL-KKIYADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPD-TPATMF--LRTTKEECELASPGTAASENESSVSPSFANEVKKED
VYSAHHSIS------LEA-------ASPGLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------IERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENMLEPSISLSEPLMLEEPE
KEEIETSLPIAITPEPEDSNLVE-EEIIELDYPESPLVSEKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------KEEELILPLLAAS-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELQE----QEG------------------
----------------KPVPPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAAPASDR--------------------------------------PLSPSTTEKTSEN
QSPLFSTVTPEHMVLSGDEASES-----GCYTPDSTSAS--------------EYSVPSQ
ATKESL--KKTIDRKSPLIS--KGVSEYMIPSEE-KEDTGSFTP---AVAPASEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSERFTPDSKLISKYAAPLNATQESQKEI
INEASQFKPKGISEHTVLSVDG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
PSSPDL-VVASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEEA
V-----ELEWYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPMNLSEED--QEDIGPFSPDSAFVSEFSFPLYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---IPV-SEQFS--SSQKQKAETFPLMSP--LEDLSLPPSTD--KS
EKAEINPEIPTTSASVSEYLILAQK-------QKTQAYL-EPESEDLIPSHLT-------
--------S---EVEKGEREAS-SSVAAIPA--ALPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---KKMEPQPPN--
--VPESEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSKNEP---EVIKPYSP
LKETSLSGP----------------------------EVLS----------AVKMEMKHD
SKITTTP----TMLHSASSGVEKQVE---------------------------------H
GPPA--------LAFSALS--EEIKKEIEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTRAVKEEIPTDS-------
-----------------------------------SLVTPVDC-PVLTEVGK-------G
ELGSGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSLPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------HSDESEEARVE------DKQGL
LFSTVRDSECLVSSQKKSLMSTSEVLEPEHELSLSLWGEIKKKETELPSSQNVSPASKHI
IPKGKDEETASSSPELENL-ASGLAPTLLLLSDDKNKPAVEVSSTAQGDFPSEKQDVALA
E-----LSLEPGKKDKPHQPLELPN---AGSEFSSDLGRQSGSIGTKQAKSPITETEDSV
LEKGPAELRSRE-GKEENRELYA--SSTM-PAISELSSLLREESQNEEIKPFSPKIFSLE
SKEPPASVAEGGNPEEFQPFTFSLKGLSEEVSHPADFKKEGNQEIGPLPPTGNLKAQVMG
DILDKLSEETGHSN--SSQVLQSITEPSKIAPSDLLVEQKKTEK----ALHSDQTVKLPD
VS-----TSFEDKQDLGIKQFSLMRENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEQRIAGSVQLDSSGS--NELRPGQLKAAV----------------
-SSKDHTCEVRKQVLPHSAEKSHLSSQEAVSALDTSSGNVQTLSSKSYSSEEVKL-AEEP
KSLVLAGNVERNIAEGKEIHSLMESESLLLEKANTELSWPSKE-DSQEKIKLPPERFFQ-
KPVSGLSVEQVKSETISSSVKTAHFPAEGVEPAL-GN---EKEAH-RSTPPFPEEKPLEE
PKMVQSKVIDDADE-----GKKPAPEV-KIPTQRKP-ISSIHA--REPQSPESPEVTQKP
PTQPKVA-KPDLPEEKGKKGISSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPSPSVEK
AVTVI-DPEGTI---P-TNFNIAEKPADHSLSEVKLKTADEPRGTLVKSGDGQNVK-EKS
MILSNVEDLQQPKSV---SEVSREDYGKKEISGDSEEMNINSVVTSADGE-NLEIQSYSL
IGEKLVMEEAKTIVPPHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KQKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKPESIILPVEESKGILID
FSEDRLKKEMQNPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVLAEKQNSV-AP
LELRDSNEIGKIQITHGSRSTELKESKADAMPQHFYQN-EDYNERSKITVGSE-------
------KENQVYVLSEGKKQQEHQPYSVNVAESMIRESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLP--------VALSCRDEIE
NHSLSQEGNLVLEK--SSRDMPDHSEEKEQFRESELSKGGSVDATKEIVKQGFQEKAVGT
QPHPLEESKVLVEKTKTFLPVVLSCHYEIENHSLSQEGNLVLEKSSRDMPDHSEEKEQ-F
KESELSKGGSVDITKESMKEG----------FPSKESERTLACPFDETKSSETPPYLLSP
VKP-----QTLASGASPEINAVKKKEMPRSEL-----------TPE--------------
---------RHTVHTIQTSKDDTS-----DVPKQSVLVSK----HHLEAAEDTRVKEPLS
SAKSNYA-QFI-----SNTSASNADKMVSNKEMPKEPEDTYAKGEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDE--KVTPLKE-NKQKETH---------ETKEEIST
DSET-DLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
TEETISFPVSSVESALEHEYDLV-KLDESFYGPEKGHDIL-SHPETQS----QNSAD--R
NVS-KDTKRDVDSKSPGMPLFEAEEGVLSRTQIFPTTIKVINPEFLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGKDDSYQPIAA--EGEIW---GKFGTICREKSRE-EQ-KGVYGEGESVDH
VETIGNVA-MQKKAPITEDVRVATQK-ISYAVPFEDTHHVLERADEA-------------
-------GSQG------NE------VG---------NASPEVNLNVPVQVSFPEE-EFAS
GATHVQETSLEEPKILVPPEPSEE--RLRNSPVQDEYEFTESLHNEVVPQ-DILSEE-LS
SESTPEDVL-SQGKESFEHIS--ENEFASEAEQSTSAEQKESGSERKEEDQLSSE-VVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIRGLQLKVNVQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLIFINAESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------DGDDEATRELETEEESE----GEEDET----AAESEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
QEGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKGSPLTSASQILTTEKEKSYT---GVYDKARK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKG-
----------SESLT---------SMFSYEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QRIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPS-TPATVF--LRTAKEECELASPGTAASENDSSVSPSFTNEVKKED
VCSAHHSIS------LEA-------ALPGLAASTQDG----LDSDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIETSLPVAATPEPEDSNLVE-EETIELDYPASPLVSKKPFPPRM-SPEVEH------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYLAP----------QDLNHELEK----RES------------------
----------------ESVSPSDVEAIAEHAVLS---------------EEENEELEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSLLFSTVTPEHMILSGDEASES-----GHYTPDSTSAS--------------EYSVPSQ
ATKESL--KKAIDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTP---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSECFTSDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKDS------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VIASEHTVLSVE-GKEDIG
PASPDS-VVASEHS-FPP--------HTTKMTSECQDPPL-----SATPSEYVVLSDEET
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCV
SEADEEDI-GSTAA---TPV-SEQFG--SSSKQKSETFPLMSP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPPHLT-------
--------S---EVKKGEREAS-SSVTAIPA--SLPAQSSIVKEETKPTSP---HAVLPD
SV-------------------PAIKKEQEPTAALTLE---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHGS------QD---QKMEPQPPN--
--VTGSEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKSKLVLNVTS--ELEQRKLSENEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSALS--EEVKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVDH-PFLTKVGK-------G
DLGSGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-SASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKAGLSVIKTS-SQ------------------YSDESEEARVE------DKQGL
SCSTVRDSERLVSSQKKSLVSTSEVLGPEHELSLSLWGEIKKEETELPSSQNVSAASKHI
IPKGKDEEIASSSPELENL-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDVALA
E-----LSLEPEKKDKPHQPLELPN---AGSEFASGLGKQSGSIGTKQAKSPITETGDSV
LEKGPTELRSRE-GKEENREFYA--FATM-PTTSELSSLLREESQNEEIKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPAHFKKGGNQEIGPLPPNGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLLVEQKKTKK----ALHSDQTVKLPD
VS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFFSPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEKLKL-AEEP
KSLVLAGNVERNIAEEKEIHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVRTAHFLAEGVEPAL-GN---EKEGH-RSTPPFSGEKPLEE
SKMVPLKVIDDADE-----EKKPAPEV-KIPTQRTP-ISSLHA--KEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKRKIGISSFKSWMSSLFFGSSTQDSKVAEQ-EDL-ETLPSPSVEK
VVTVI-EPEGTI---P-TNFNVAEKQADRSLSEVKLKTADESRGTLVKSDEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEMNINSVVTSADGEKHLEIQPYSL
ISEKLIMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNLASKNI------------TKESEKSESIILPVEESKGSLVD
LSEDRLKKEMQSPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNKIGKTQITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEEKKKQEHQPYSVNVAESMIKESGI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLSEAHPEIREAKAVATQPHPLEESKVLVEKTKTFLP--------VALSCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMPDHSEEKEQ-F
RESELSKGGSVDITKESMKQG----------FPTKESERTLAYPFDETKSSETLPYLLSS
VKP-----QTLVSGASPEINAVKKQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTL-----DVPKQSVLVSK----HHLEAVEDTRVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDSDEKVTSLKEKSKQKETR---------HTEEKTST
DSETGDLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEDKLSEEV
TEEAISFPVSSVESSLEHEYDLV-KLDESFYGLEKDHDIL-SHPETQKSL-----AD--R
SVS-KDVKRDVDSKSPGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYQDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVGH
VETLGNIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPQVNLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILGPPEPSEE--RLRNSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAGQKELGSERKEENQLSSE-LVTE
KTQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKKLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----VSL--------YSPDR
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGVVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MQECIMSDPTFSMVTVQREDSGITWETSSSRSSTPWVSEESQTSGMCS
LEGSNV-SSPPGSVSFIVDEVKKARKRTHK--SKHGSPS--LRRKGSKKRNSFEFP-DVS
ANKKDSSLTSESQAVNTEKEKSSP---GLYDKSRK----KKTTSNMPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNRGSDIVSKTSKL-----VTQSTEDG----------------KVGERGTLWRGTLSKG-
----------SESLT---------SLFGHDDG-EKIDAESSLKGT--PAAG---------
-----------------PAASHYLSNDAAA---PGLLLRSPQAM----------PQQPGQ
ESEAHDEGPSSPPPE-VSVAGS--LETAKEESEAEAEGAVGLEMDSSVSSALVGEVMKEV
MASADHAKS------LEAEKDLLGTGSLALSPPTQEA----LEPGKEELQLASLEKMEPA
SGHVAPT-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------HPGV-------------QGEKEETGFMPPISLHEPLLCQEPE
QEELETSPPIPATPEPEGSDLE--EEIIELDYPESPLVSEQPFPSRL-SPEVLH------
------------------------------------------------------------
---------------HEE-PTPASLTKA-------------APDHATLSDDERE----EM
ESVSPDSAFVSEYSAP----------QDLNDELEK----QES------------------
----------------KPVSPSSTKALSEHAALS---------------EGENEEFKPRS
LAVASAPEH--------------------------------------SLSPPTPEKPSGG
LSPLFSAVPSEHLVFSGGEASES-----ERHTPDSTSVS--------------EHSVPLH
EVQESL--KETFD-KSPLKS--KGVSEHVILSEE--KDTRSQYP---AVASVSKCSVSPP
LMEQTPECQSPLPPA-ATLKHMVLSEKEG-LPSQPLIPDSKLTPKPEVLLHATQESQKKI
TDEAPQFKSEGISEHMTLSETE--------------------------------------
------------------------------------------------------------
---------KESTGPCAPDVATASERFLPLDTDRTP--GYQPSPPAA-TLQHVVLSEK-E
DLPSKPLISDSELTPKSAVPLNATQESE-KKTINEMPQFKLKDRFEHMILSET-EKEDVG
PYSPDVQVPAPEGS-PLP--------QTPEMTSEYQAPPL-----PGTLSEHVVLSEEET
T-----EMKRCSPSSA---------SAS-EFSIPPHATPESQEEEIVQRSPLHLK-----
------------------------------------------------------------
----GASSPMNLSEQ----EDIGPFSPDSAFVSEFSFSPSPTQEAEKRESECGSPVCLTS
PCEHMVLSDEDTEDAGLFSSDSAS--QVSVPPYKIPETEMNESEPESIVTTRSASGFSYF
SEADEEEL-GSTAA---TPI-PEDFD--SSEQQKAEPCPAMST--PEDLSLPSSGD--KA
TSAAAGTDVQTFSTSVSEYFILAQQ-------QKSQAPL-EPEAEDLVSLYLT---N---
------------RSEQEEMKANSS-AVATH--AASNVQSSLAKEETKPVLPVPQYSVSLD
SI-------------------HATKKEQEPKASLTLK---------AADEQM--------
-ALSRVR---------------KEEAVPDSQEAIAHVS------QD---QKLEPQPPN--
--VPESGTKYSVLPEL-VD-----------------------------------------
-------------------EPKKDVKLSLAPTVPS--ELEQTLLSKNEP---EVVQAYSP
PRESSISGP----------------------------EVLS----------GVNTEVRHD
SKIA-------RELHSASSRAQKGVE---------------------------------H
GPPT--------PTLSALS--EEIKKEMEPSSLTT-TS-VTK---------CDS------
------------------------------------------------------------
---------------------------------------NLTTLVKD-I-----------
------------------------------P-TGPSPATPVEEHLVSTRAGK-------G
ELGSGLP----------------AF--RKGRDEHSILKEEEKLAI---------------
---TS-TSSQIEASSSKGLVP--SEVE-----EETK-------IDSPPSVCSIAEHSILS
TVDTEEVQSSLLVNQMSSPQ------------------LSAVSEGVSGK------DKQGL
SLSVALDSTHVVSSQGKNSVSTSEVSRPEPVLSFSLGSGTEKEETRLLSSHTVSPAPKHV
VPRDKNEVMTSSSPEFENLVSEDLVPTPQTLGDDKNKQVWDTTSAVHGDFLLGKEDLAPA
E-----LPLESEKKDKLHQLSELSK---AGSELTGGLGRQSEPVDTEPVASLITDTEGSI
LEKGLAELRSRGEENEENRELFV--SATE-------------------------------
------------------------------------------------------------
--------------------------PSKIASFDLHAEQKKPEK----MLSSDQAVDLSD
AS-----TSCEDKPDLNIEQLPSMKENLPWEQSQSFVTPEPEPLESSS------------
-------------------------------PIDLLIRQLQAAP----------------
-SDEGRTYEIGKQVLPPAMEESHLPLEEPASTPGTSEGNTETLSTETYSFEEIKV-VQEI
KSLGPAGNLERNTQK-GHIHPFMESESFILERTDTDFSRPSKE-GIQEEVKPPPEAPTQ-
EPVSGPSAEPVKLETTPSPVKAPHFLVEAVEPAL-YS---EKEAH-RDTPP---EKPQEE
SKMVPSKIIDEEAK-----GRKSVPEV-KILTQTKP-ICSTQA-GEDHQPPETPEVTQHL
HEKPKVA-EQRLPEEKGKKGLSSFKSWMSSLLFGSSTSDAKVAEK-EDL-DTQQSLSVEK
AVTVI-EPKGKI---P-ADFNATEKPANHSLPE---------------------------
--------------------VSSEDYRKNEIPDSSEKMGINLV-TSADSEEHLRIQPD--
--KRLVMEETKN-IPSHVTESKRYQKP------------TIAPPTNWNISILRKGPS--G
DE-----------------------------------------------------KEK-S
FSFDVVDKMSQQLKTDSFNFTNKNI------------MKESEKPEPINLPVEESKGSLID
LGEDRLKTEVPKLTSLKLSEEEVKLRPVSPKEQKGNLETGSCTLAEKSDLADRQEVA-FP
LELRQNKELVKAQMTQEYRPITLEESKIAARLEHIYPK-EDHKERAKIIVCSE-------
EKG-EEKEKQAQVFWEEKKEQEDQPYSLNVARCVPEEPVI------------------S-
--PLHSLG-D-----AQPFSFIKTTAVTEKPES---------------------------
-----VLSEAHPGIKERKVLESQPHLLEENESFVKKTKTLCP--------VNLPYHDEID
KHPSPLEENLVLEK--P-------------------------------------------
---------------------------------------------SRDIAGHREERGHSV
TVSQLCTSGLVATTKESMRRA----------SPSEEPERTVGHPSDDMESLEMPLYLRSS
VKP-----QTHVPGVCPEVNTEKKQEMPWSEL-----------TPG--------------
---------HPTVHTIQTSEDHPS-----EMLKQPVLVSK----HSLETMEDAHINKPVS
SAGSNYA-QFI-----ISASRSTADEMV--KEMSTEPEDTYARDVES-------TVTSKP
AGL---SQDQKSAFSIISEGCEILNIHAPAFIPSVDQEECEKMQDKLEYLESKT---AI-
TLHDDSEAIVRHKMLQ-RNL---EDSGGKVTQLKE-NEEKGAH---------VTKEELSL
DSDTGDLAFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPWKLT-MKEVLSKGA
TGETLTFPESPQESSLEHAYDLV-KLDESFYGPEKDHSQL-SQPEMEKSLVTQHSAD--R
NAS-KSINRDVDSRLPGMPLFDTEEGVLSRAQIFPTTVKAVNPELLQEPPALSFLYKDLY
EEAAGEKQKEEERASEGDSVSSEAPFPCRDSDTDDGTGMYFEKYTLRDDILHDTSVMHKD
QGQGLEEKPVGKNDSYQLIDT--EEEIW---RKSGT-IWEKSLD-EQ-KAIYREGEAVGH
VETSDDTA-V-QAAPITEEVSVVVQK-ISYAVPFQDDRNVLESIAEV-------------
-------STQG------HE------AG---------NTSPEVSQNVPTQVSFTDE-AFAS
SAAYIPETPQEEPQVLVSPTPSEQ--RFRNSPVQDEYEFAEPLSYEVVSQ-DILPDV-PY
SDSANEDVL-SHGKEFFEHIR--KCEFLSEAEQTVSADQSELGRRRTEQDQLSSE-LVTE
KAQKEPKKTQIDTYCYTCKSPVSTMDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEESCTKNEKRLEEQNEEMMRKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLEAIVREAEELDE--TVFLT----SFE--------EINER
LLSAVASTASLEHMPAAFSLFEHYEDATARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDIIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKETYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVFRAEDCTVCWNMATIRWRPAN--SEAT
ESYTVEYCRQHSPEG-EGLRSFSGIKGLQLKVKLQPNVDYLFYVRAMNVFGTSAQSDTAL
ISTR--GTRFLLLRETAHPALQISSDGTEISFTERRRLTEIPSVLGEELPACGLHYWETT
VTNCPAYRLGICSSSAVR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPGRVGILLDYAGQRLAFINAESGQLLFLVRHRFSEGVHPAFAMEKPGTCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASDDSG-----
--LAAQGFLGW-------GADEEVAQELETEEESE----GEGEET----AAESEEEPDA-
-RLSDEDEEGKTKQECIVSDPSFSMVAVQREDSGITWETNSSRSSTPWASGESQTSGICS
LEGSAL-TSPPGSVSFIMDEVKRTRKRTQK--SKRGSPS--LRRKGSKKRNSLESP-DVL
TTQEDGPLISESPVLNTEKEKSSI---GTYDKTRR----KTTASNTPPITGAIYKEHKPL
VLKPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKD--SSISLEPDL
SNSGSNIVSQR--K-----LAQSPEED----------------KVRELAPPWRGALSKG-
----------ST--T---------SLFSHEEQ-KKTYADSHFNVP--SSKE---------
-----------------HTFPSNARNDTAD---QEEKLRLPQMM----------PQQPDD
ESETHRTEPPS-----TPAT--MVLERAKEELEQNAQEKESSEDDASVLTGSAEDVQREG
LVSVNHSMP------WEAEKESLETGPPRPAPDIQEK----FEPDMEGLELISTEKTEQV
SEYVTSSEPIVHREEEHAP---EPIVRREEEHAPE--PIVHREEEHAPEPVVHREEEHAP
EP------------VVHREEEHAPEHIVHREEEHAPEPT---------------------
------------------------------------------------------------
---------------------------------------EHAPEPIVHREEEHAPEPIDL
REEEHAP-----------EPTVHRK--------------EEHELEPLLSLA-----SQQL
ERGVETSTPITDTTEPEDSSLE--EEIIELDYPESPLVSKKTSPSPL-SPEVEH------
------------------------------------------------------------
---------------RKE-SILPTQMTF-------------TPEHSTLSEEERE----EN
ESVSTDSAFVSEYSVL----------QDLNRTPEK----LEV------------------
----------------EAVSVSDVKSSPEPAVFS---------------ED-DEEHKPYS
PALTSVSEQ--------------------------------------SLSPSTTEKTSAT
QAPPFSPVS---PVLSGDEASES-----VCHSPDSESAA--------------EYSIPAH
A-QELL--VKTGDHKLSLKP--QHVSEPMIQAEDENEDIGLLSP----------------
----------------AALRHAALSEDEG-LESESFASDSKLPFKPSVPQNATQESPPKT
IDDMPQFKPKGLSDPATLLEEE-KEAI---------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------GVE
LSSSNA-VSAAERA-LSP--------QTTEMLSERQAPPP-----WATSSEQVVPSEEGS
G-----DGQQRTFS---------------------------STPELVHTSPLLLK-----
------------------------------------------------------------
----DASSPTGLSEQGQEEDNIGPLSPDSAFASEFSFSPYPTQELEKRELGRDSPLCLTS
PSEQTVLSDEDTEEAELFSPDSAS--QVSIPPYRIAETEQNKVEPDDLLPTRPAPDYPYF
SEADEEEV-GSSVV---TPV-PEHSG--PSQAWEKESYPSRPV--FEDLSLPPSTD--KT
GKAETTLDVPTISTSVSEYLILAQQ-------EKTQASL-EPEAEDSVPPPTS-------
------------GWEKRDAKSGLPAV---TIAASSSALSSVVKEETTSVLPTSQSSVSPE
SA-------------------RVLKTEQEPTASLTLT---------SADEQM--------
-ALPKVR---------------REETVLDSQEATAHEL------QD---QTPEPQPPN--
--VPGSGMKYSVLSDL-GD-----------------------------------------
-------------------EPKADVKLNLAPTVTS--EPEQRMLSKNEP---KVAKPYSP
PEETSISGP----------------------------KVLS----------AVKTEVKQE
SKIT-------RELPAASSEIEREVE---------------------------------H
CPPAP-------PALPVLT--EETGKDTEASSSATTVP-VTK---------LDS------
------------------------------------------------------------
---------------------------------------SSTELGRDEILTDP-------
-----------------------------------SLASPAEH-PGLKRVGK-------S
ELGSRLPSPSM-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------SASEVLRPEPILPVNSGGEAEREDRE-PPTLQVSPTSKHT
VPNDKHEEIT-RSPDSENLVSDNLAPTLLALRHEMNRQAEETSSPVPGSFLSGKQELT--
K-----LPREP---EKHKQLSEVPT---TGSELIDSRDR-DRSLGIEPVKPTGMEPEPSI
LEKGPSELRRRGKDQEENRELPV--P----------------------------------
------------------------------------------------------------
--------------------------PLETASFDLPIEQKELRR----TLHEGQAVEVPD
ES-----SSSADKPELGDKQLT--EK-----QPKPFVTTERASVTGSKVKEGLISLKD-N
TWVLEKPGGL-VNQH-------GQPESSES--TALVSEKLGAAP----------------
-LDTDHTSEIRNQEASKAPVPGEKPSQEPPVPGEKPSQ----------------------
------------------------------------------------EPPVPGEKP---
----------------------------SQEPPV-PG---EK---PSQEPPVXGEKPSQE
PGRVQSKAVDDSEE-----GRKPASGNVEELTQSKS-VPAVKA-NAIPQPPATPEVTQKP
PEKSLVA-EQGLPAEKGKKGISSFKSWMSSLLFGPSIPDSKVSDD-KDL-ETRPSPSAEK
AVPAI-EPKGTA---P-AEGNAAEKPAVHSLPEVTVKLAEEPKGVSVKSSVSQDLR-EKL
TFLSNEDVLKQPKSS-------SENYGQKDLPGFSEGMGESL--ATSVGDKHPGIHPCSP
TGEKVGMEEAQNMAPLRITESQRHQKT------------EISPPSMWGISARKEEPS--S
DH-----------------------------------------------------KETRL
PSSDVVDRMPQWPESAQSAFTRM----------------DSEDPASVILPV-ESKGSLSH
LGEDRLRQEMPKPTSPEHCEEEVER----PTEEKDDWETRSFSLAGKRGLAEKQEIT-AP
LELRGNEAVGELQTMPESRPFKSEESKAAERLEQRISPSEELMEKPSKTLA---------
-LDRREKEMQEWVFSEGEKQGYP-PAAMP----VPGA-----------------------
--SAVSLD------KAQPQLLAKPTPVVEKPEH---------------------------
-----IFTEIYPEIRERKAAETQPHPQEEGKTLVEKTKDSC---------VESPHGEEMD
SHSVTQGGSLELEK--SCE-----------------------------------------
-----------------------------------------------SRVALKEERRQ-F
VMPELSLGASVTAEDGTVQPG----------PLSRDSDRTSEHMTDETKDLGT-RTQLSA
VEP-----QTLVLGTSVEHTV-KK-QETW---------------SN--------------
---------RPTVHTFQTSKDHPE-----EMLKQSVLISK----PHLEAVEDVHRNEPPS
SAASNYT-QFM-----LSESEVSADGAPPRGGTAQEPEGTSVKDEEF-------SVTSKP
AGL---SEHQKSAFSIISEGCEILNIHAPAFIPSVDQEASEQMQDKLQYVEEKASFKSI-
SVRDEKKAVASHKTQK-SKL---EVPDRKVTSPRE-DEPQETP---------KTKEEVAT
ESGMGDFTPTQPTV----SG-EEDYFEKYTLIDYNLSPGSEKQKPPVEE------SSEEA
TKTLTSFPESSAEQALDHEYNLV-KLDESFYGPEKDGSQL-SHAEMQTSLVIQKPDD--R
NAP-KGISRDVDSKSPGMPLFDVEEGVLSKRQIFPTTTKAVNPELLEEPPALSFFYKDLY
EGACGEK-NEGETASEGDSVDSETSFPRRHSDTDDGPGMYFEKYILKDDILHGKSVTQED
QGQGLEEKPGGEEDSQQLRVA--EREIR---RKPETSFWEKDLEEQH-KVVGREGEPTGH
METLDEVA-MQQKAPITEQVRAVTQK-MSYAVPFQDTRCALES--EP-------------
-------SCQG------NE------AG---------NASPDVNLNVPVQVSFPEE-EFAA
GATYAPEVSQE---RLVPSVSREE--RLHNTPVQDEYDFVGSLNQEAASQ-AILPEE-PC
SESSPKEVL-SQGTESFEHIR--EQEITSGGDPRMSALQEAWDRRT--EDLSARD-SVTA
KTQKEQKKAQVESYCYTCKSLVSETDKALDIHKDHEVSALDTAISAVKVQLGEFLENLQE
KSLRIEAFVSEIESFFNTIEEKCSKNEKRLEMQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLETIVREAEELDE--TVFLA----HPHAGPWACPVNSHLR
LLSAMESTASLENMPAAFSRFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPSSATSTT-
-IAVYWSVNKEDVVDSFQVYCVEEPQDDQEI--NELVEEYRLTVKESCCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIHVEDCTVCWNSATVRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLPPNDNYFFYVRATNASGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISANGTVISFSERRRLTEIPSVLGEELPACGQHYWETT
VADSPAYRLGICSSSAVR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSE---VHAT
ERPARVGILLDYTNQRLLFINAESGQLLFIVRHRFSEGVHPAFALEKPGRCTLHLGVEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------DGDEEATRELETEEESE----GEEDET----AAESEEEPDS-
-RLSDQDEEGKIKQEYIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNRKRNSFESQ-DVP
TNKKGSPLTSASQVLTTEKEKSYT---GIYDKARK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSGSNTVSKTRKL-----VAQSIED-----------------KVKEVFPPWRGALSKG-
----------SESLT---------LMFSHEDQ-KKIYADSPLNAT--SALE---------
-----------------HTVPSYSSSGRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPD-TPATMF--LRTTKEECELASPGTAASENDSSVSPSFANEVKKED
VYSAHHSIS------LEA-------ASPGLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------IERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENMLEPSISLSEPLMLEEPE
KEEIETSLPIAITPEPEDSNLVE-EEIVELDYPESPLVSEKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------KEEELILPLLAAS-------------SPEHVALSEEERE----EI
ASVSTGSAFVSEYSVP----------QDLNHELQE----QEG------------------
----------------EPVPPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAAPTSES--------------------------------------SLSPSTTEKTSEN
QSPLFSTVTPEYMVLSGDEASES-----GCYTPDSTSAS--------------EYSVPSL
ATKESL--KKTIDRKSPLIL--KGVSEYMIPSEE-KEDTGSFTP---AVAPASEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSERFTPDSKLISKYAAPLNATQESQKKI
INEASQFKPKGISEHTVLSVDG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEVIG
PSSPDL-VVASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEEA
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPMNLSEED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKAETFPLMSP--LEDLSLPPSTD--KS
EKAEIKPEIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPSHLT-------
--------S---EVEKGEREAS-SSVAAIPA--ALPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--VPESEMKYSVLPDM-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSKNEP---EVIKPYSP
LKETSLSGP----------------------------EALS----------AVKMEMKHD
SKITTTP----IVLHSASSGVEKQVE---------------------------------H
GPPA--------LAFSALS--EEIKKEIEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTRAVKEEIPTDS-------
-----------------------------------SLITPVDR-PVLTKVGK-------G
ELGSGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSLPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------HSDKSEEARVE------DKQDL
LFSTVCDSERLVSSQKKSLMSTSEVLEPEHELPLSLWGEIKKKETELPSSQNVSPASKHI
IPKGKDEETASSSPELENL-ASGLAPTLLLLSDDKNKPAVEVSSTAQGDFPSEKQDVALA
E-----LSLEPEKKDKPHQPLELPN---AGSEFSSDLGRQSGSIGTKQAKSPITETEDSV
LEKGPAELRSRE-GKEENRELCA--SSTM-PAISELSSLLREESQNEEIKPFSPKIISLE
SKEPPASVAEGGNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DILDKLSEETGHPN--SSQVLQSITEPSKIAPSDLLVEQKKTEK----ALHSDQTVKLPD
VS-----TSSEDKQDLGIKQFSLMRENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEQRIAGSVQLDSSSS--NELRPGQLKAAV----------------
-SSKDHTCEVRKQVLPHSAEESHLSSQEAVSALDTSSGNTETLSSKSYSSEEVKL-AEEP
KSLVLAGNVERNIAEGKEIHSLMESESLLLEKANTELSWPSKE-DSQEKIKLPPERFFQ-
KPVSGLSVEQVKSETISSSVKTAHFPAEGVEPAL-GN---EKEAH-RSTPPFPEEKPLEE
SKMVQSKVIDDADE-----GKKPSPEV-KIPTQRKP-ISSIHA--REPQSPESPEVTQNP
PTQPKVA-KPDLPEEKGKKGISSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPSPSVEK
AVTVI-DPEGTI---P-TNFNVAEKPADHSLSEVKLKTADEPRGTLVKSGDGQNVK-EKS
MILSNVEDLQQPKFI---SEVSREDYGKKEISGDSEEMNINSVVTSADGE-NLEIQSYSL
IGEKLVMEEAKTIVPPHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KQKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKPESIILPVEESKGSLID
FSEDRLKKEMQNPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVLAEKQNSV-AP
LELRDSNEIGKTQITLGSRSTELKESKADAMPQHFYQN-EDYNERPKIIVGSE----KEK
GE---EKENQVYVLSEGKKQQEHQPYSVNVAESMSRESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLP--------VALSCRDEIE
NHSLSQEGNLVLEK--SSRDMPDHSEEKEQFRESELSKGGSVDITKETVKQGFQEKAVGT
QPRPLEESKVLVEKTKTFLPVVLSCHDEIENHSLSQEGNLVLEKSSRDMPDHSEEKEQ-F
KESELWKGGSVDITKESMKEG----------FPSKESERTLARPFDETKSSETPPYLLSP
VKP-----QTLASGASPEINAVKKKEMPRSEL-----------TPE--------------
---------RHTVHTIQTSKDDTS-----DVPKQSVLVSK----HHLEAAEDTRVKEPLS
SAKSNYA-QFI-----SNTSASNADKMVSNKEMPKEPEDTYAKGEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDE--KVTPLKE-NKQKETH---------KTKEEIST
DSET-DLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
TEETISFPVSSVESALEHEYDLV-KLDESFYGPEKGHNIL-SHPETQS----QNSAD--R
NVS-KDTKRDVDSKSPGMPLFEAEEGVLSRTQIFPTTIKVIDPEFLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGKDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVDH
VETVGNVA-MQKKAPITEDVRVATQK-ISYAVPFEDTHHVLERADEA-------------
-------GSHG------NE------VG---------NASPEVNLNVPVQVSFPEE-EFAS
GATHVQETSLEEPKILVPPEPSEE--RLRNSPVQDEYEFTESLHNEVVPQ-DILSEE-LS
SESTPEDVL-SQGKESFEHIS--ENEFASEAEQSTPAEQKELGSERKEEDQLSSE-VVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFGERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLIFINAESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MESGDSG-----
--LAAQGFLGW-------GADEEVAQELETEEESE----GEGEET----AAESEEEPDA-
-RLSDEDEEGKTKQECIVSDPSFSMVAVQREDSGITWETNSSRSSTPWASGESQTSGICS
LEGSAL-TSPPGSVSFIMDEVKRTRKRTQK--SKRGSPS--LRRKGSKKRNSLESQ-DVL
TNQEDGPSISESPVLNIENEKSSI---GTYDKTRR----KKTASNTPPITGAIYKEHKPL
VLKPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKD--SSISLEPDL
SNGGSNIVPQR--K-----LAQSPEED----------------KVRELAPPWRGALSKG-
----------SR--T---------SLFSHEEQ-KKTYADSNLNVP--SSTE---------
-----------------HAFPSSARNDTAD---QEENLSLPQMM----------PQQPAD
ESKTHRMEPPS-----IPAT--MVLERAKEELEQNAQGKESSEDDASVLTGSADDVQQEG
LVSVNHSMP------WEAEKESLETGPPRPAPAIQEK----FEPDMEGLEPISTEKTEQA
SEYVTSSEPIVHREEEHAP---EPIVHREEEHAPE--PIVHREEEHAPEPIVHREEEHAP
------------ESIVHREEEHAPESIVQREEEHAPEPESIVHREEEHAPGP--VPIVHR
EEEHVPELESIV--------------------H--R--G--E--E--H-A--P--E--P-
-I--V--H--R--D--E--G--------------------HAPEPIVHREEEHVPEPIVH
RDEGHAP-----------EPIVHREEEHVPEPESIVHREEEHAPEPMVLRK-----A-QL
ERGVETSTPITDTTEPEDSSLE--EEIIELDYPESPLASKETSPSPL-SPEVEH------
------------------------------------------------------------
---------------RKE-PILPTQMTF-------------TPERITLSEEERE----EN
ESVSTDSAFVSEYSVL----------QDLNHTPEK----LEV------------------
----------------EAVSVSDVKSSNEPAVFS---------------ED-DEERESYS
PAMTSVSEQ--------------------------------------SLSPSTTEKTSAI
QSPLFSTVS---PVLSGDEASES-----VCHSPESESAA--------------EYSVPAH
A-QELL--LKTGDHKLPLKS--QRVSEPIIQAEDEKEDIGLLPP----------------
----------------AALSQAVLSEDES-LGSGSFASDSKLPFKPSVSQNATRESPQKT
IDDMPQFKPRGLSDPATLLEEE-KEAI---------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------GVG
LSSSNE-VSAVECA-LPP--------QTTELLSESHAPPP-----WAISSEQVVQSEEGS
R-----DQQRGSFS---------------------------STPELGHTSPLLLK-----
------------------------------------------------------------
----GASSPTGLSEQGQEEDNIGPLSPDSAFASEFSFSPYPTQELEKRELGRDSPLCLTS
PSEQTVLSDEDTEEADLFSPDSAS--QVSIPPYRIAETEQNKVEPDELLPRRSAPDYPYF
SEADEEEA-GSSVV---TPV-PEHSE--PSQER-EESSPCRPV--FEDLSLLPSAD--KT
GQAETMSDVPTISTSVSEYLILAQQ-------EKTQASL-EPEAEDLVPPPTS-------
------------GWEKRDAKSSLPAV---TIAASSSALSSVVKEETTSVLPTSQPSVSPE
ST-------------------CVLKPEQEPTAPLTLT---------SADEQM--------
-ALPRVG---------------REKAVLDSQEATAHKS------QD---QTPEPRLPN--
--VPGSGMKYSVLSDL-GD-----------------------------------------
-------------------EPKADVKLNLAPTVTS--ELEQRMLSKNEP---EVAKPHSP
PEETSISGP----------------------------KVLS----------AVKTEVKQE
SKIT-------RELPAASSGRERGAE---------------------------------H
SPPAP-------PALPALM--EEMGKDTEASSSATTVP-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NSTKLGRDEVLTDP-------
-----------------------------------SLASPVEH-PGLKGVGK-------S
ELGSGLPLPSM-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------STSEVLRPEPKLPVNSGVEVEREDNE-PPPLQVSPTSKPT
VPNDKHEEIT-RSPDSENVVSDDLAPTLLALRHEMNRQAEETSSPVPGSFLSGEQELI--
K-----LPPEP---EKHKQLSEVPT---AGSELIDSRDR-DRSLGIEPVKPIGTEPGPSI
LEKGPAELQRRGKEQEENRKLPV--PASA-------------------------------
------------------------------------------------------------
--------------------------PLETASFDLPIEQKEPKR----TLHEGQAVEVPD
ES-----SSSADKPELGVKQLA--EKKENLEQPKPFVTTERASVTGSKVKESLISPKD-N
TWMLEKPDGL-VNQHEDRKPGTGQLESSES--TDLMSEKLGAAP----------------
-LDTDHTSETRNQETSKAPVSGE-------------------------------------
------------------------------------------------------------
-------------------------------------------------------KLSQE
PRRVQSKAVDDSEE-----GRKLASGNVEVLTQSKS-VPAVKA-KATPQPPETPEVTQKP
SEKSLVT-EQGLPAEKGKKGISSFKSWMSSLLFGSSIPDSKVSDN-EDL-ETRPGPSVEK
AVPAI-EPKGTV---P-AEVNIAEKPAVHSLPEVTVKLAEEPKGVSVKSSISQDLK-EKL
TFLSNEDVLKQPKSN-------SENYGQKELPGFSEGMGESL--ATSVGDKHPGIHPCSP
MGEKVGMEEAQNMAPLHITESQRRQKP------------EVSSPSMWNISARKEEPS--S
DH-----------------------------------------------------KETWL
SSSDVVDRMPQKPKSAQSAFTRM----------------NSEEPASMILPV-ESKGSLSD
LGEDRLRQEMPKPTSLEHCEEEVER----PTEEKDGWETRSFSLAGKRGLAEKQEIM-AP
LELRENEAVGELQRMPESRPFKLEESKAAERLEQRISPTEKLMEKPSKTLA---------
-LDRREKEVQEWVFSEGEKQEYP-PAAMP----VPGA-----------------------
--SAVSLD------KAQPHLLAKPTPVVEKPEH---------------------------
-----IVTEVYPEIRERKAAETQPHPQEEGKTLVEKTKVSR---------VESPHGEETD
GHSLTQEGNLELEK--SGE-----------------------------------------
-----------------------------------------------SRVDLKEERRR-F
VMPELSLGASVAAEDGSVQPR----------PLSKDAARVSD-MTDETKHLGTPPTQPSA
VEP-----QTLVLGTSVEHTV-KK-QETW---------------SD--------------
---------RPTVHTFQTSKDYTE-----EMLKQSVLISK----HHLEAVEDVHRNEPPS
SAASNYT-QFM-----LSASEISADGVPPMGGTAQEPEGTSVKDEEF-------SVTSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFIPSVDQEESEQMQDKLQYLEEKASFKSI-
SVHDEKKAAASHKTQK-SKL---EVPDRKITSLKE-NETKETH---------KTKEEIAT
DSGMGDFTPIQPTV----SG-EEDYFEKYTLIDYNLSPGSGKQKSTVEE------SSEEA
TKTLTSFPESSAEQALDHEYNLV-KLDESFYGPEKDDSKL-SHAEMQKSLAIQKPDD--R
NAP-KGISRDVDSRSPGMPLFDVEEGVLSKRQIFPTTPKAVNPELLEEPPALSFFYKDLY
EGAGGEK-NEGETASEGDSVDSETSFPRRHSDTDDGPGMYFEKYILKDDILHDETVTQED
QGQGLEEKPVGEEDSQQLRVA--EREIR---RKPETSFWEKNLEEQH-KVVGREGEPTGH
METLDEAA-MQQKAPITEQVRAVTQK-MSYAVPFQDTRCVLES--EP-------------
-------SSQG------NE------AG---------NASPDVNLNVPVQESFPEE-ESAA
GATYAPEVLQE---RLVPSVSREE--RLHNTPVQDEYDFVGSLNQEAASQ-AILPEE-PG
SESSPKEVL-SQGSESFEHIR--EQELTSEGEPRMSASQEVWDRT---EDQSARE-SVTA
KTQKEPKKTQAESYCYTCKSLVSEMDKALDIHKDHEVSALDTAISAVKVQLGEFLENLQE
KSLRIEAFVSEIESFFNTIEEKCSKNEKRLEMQNEEMMKRVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLETIVREAEELDE--TVFLA----SFE--------EINER
LLSAMESTASLENMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPSSATSTT-
-IAVYWSVNKEDVVDSFQVYCVEEPQDDQEI--NELVEEYRLTVKESCCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTAVIHVEDCTVCWNTATVRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLPPNDNYFFYVRATNASGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISANGTVISFSERRRLTEIPSVLGEELPACGQHYWETT
VADSPAYRLGICTSSAVR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSE---VHAT
ERPARVGILLDYTNQRLLFINAESGQLLFIVRHRFNEGVHPAFALEKPGRCTLHLGLEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASGDSDQ----
--AFAHSFLGS-------DGDEEAARELETDEEEE----EEEEEGELEPEEEEEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMMTVQREDSGITWETNSSRSSTPWASEESQTSGICS
LEGSTL-NSPPGNVSFIVDEVKRSRKRASK--SKHGSPS--LRRKGNKKRHSLESP-EVP
SNKKDSPLISASQTLDTEKEKSST---GIYERTSK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNVLSRRGKS-----VAQSPEDD----------------TARELAPPWRGALSKG-
----------SKSLS---------SLFGHEEQ-KKIYVDSPLNAT--SETE---------
-----------------HTVSSYSRNDSTD---QEAQLSSSKLV----------PQQPDD
KAQTLEVEPP----G-APATEF--LETTKEEFEPDMRGMESLEKDSAAFPAVVD-DKEED
VYSVSRSLS------LEAEEDSLETGSPGLAPSSQEE----FKADREELAPTSP------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------GRAEPSTR------------
--DLTSP-----------EPSI-------------QGEEEL-------------VQELPK
--EVEAS---LATDEPEDSSLA--EEIIELDYPESPLVSEKPFPPSL-SPEVEY------
------------------------------------------------------------
---------------KE--TILPSQVTS-------------TPEPVTLSEEERE----ES
ESA---------------------------------------------------------
------------------ASPSHERAISEPTVFS---------------EEENEEFEPYA
AAVASASQH--------------------------------------ALPPSTTKETLQP
QTPLFSTVTSNHLVLSGDEASGS-----GFYTPDLTSAS--------------EYPTIP-
-------------------------------STTQEEDAGPHTP---A-AVASEHSLSPS
ITEKISECKVLG--------------------SEH-------------------------
-----LTPSEGISEPMILSGEE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDSG
PYLSDV-AFASERS-LPP--------HTVEVPSECQAPAL-----STTSSEHVVLSEEET
T-----ETQCYSPSST---------LAS-ELSLPSYAAPEFQEEETVRRSPLYLK-----
------------------------------------------------------------
----GASSPTNLSEQE--QEDIGPFSPDSAFVSEFSFSPYPTQEAEKRELEFDSPIS---
-----------------------S--QVSIPPYRISQAEKGETEPDSPSTARSASGHSSF
SEADEEEV-RSMAA---TPV-PEHVD--SSQKPRAEPVPLTSA--FEAATLPPSAA--IA
EQTGRMPDASAISTTVSEYLILAQQ-------QDTQAFL---GPEDLVQPHLT---R---
------------GSEKAEMKTGS-SATTAP--SSSPVWSSTRKEETRPVLPAPESLVSPD
SG-------------------HVIKKEQEPKAVLSLK---------VTDEQT--------
-ALLKVN---------------REETVLDSQEVIAHVS------QD---HRPEPQPPS--
--VPESGMKHSVSSDL-VD-----------------------------------------
-------------------EPKKDVKPSLALSATS--DLEPRMLSKNEF---EETAPCLP
PKEASVSGP----------------------------AGLS----------GVTKEVEVD
SKIT-------RELPAASSGIEKAVE---------------------------------H
GPLA---------PFSALT--EKLKK----------------------------------
------------------------------------------------------------
-------------------------------------------AVEEEILKGS-------
-----------------------------------SPSTPMEH-PGPA------------
--RSGQ-----------------VL--VASIDEHLVPKEEEKVPL---------------
---KS-AASLIEASLSTDSAW--SEAQ-----KEIK-------LDSSASTSSTAEHSVWT
KAETEEVEPGLPVSQMSLSQ------------------DSEIC----EG------DKQTP
SFSTVLDSEHLLSSQKKDSVS--------------------KAESELPPSQNASPASKHI
VPKDEQKEIISSSPKSENLVSDDLLSTLLAVRDDMSKQAKETSPLPPRGFPSGTQG--LV
V-----LPSEPEKKHKPPQQSKLPA---AGSELSGSLGRESGPFDLEPAESPVSGSGDSV
FERDLAELRNRGKDSEENGEHRV--FSDI-PD----------------------------
------------------------------------------------------------
--------------------------------------ILKPDE----VLHSGQAAKVPD
TH-----TSLAHKPELGVKQFSDRKENLPLEHAESLMTSEPADVEGRKEKEPLISPKG-D
DWVLKKPVTV-ASHHEDRKLAPVQPDSPGSTENDVGPGQLAAVP----------------
-GDKDHTSEIRKQEKEAPLLAE--------------------------------------
------------------------------------------------------------
-------------------------------------------------------RAAPD
ARAGGLQAVCD-----AKEGRQPAPEV-KISTQSRP-VLPIQA-HEAPQPAETPEGTQKL
SEKPTVT-EKGLAEEKGKRRISSFTSWMSSLFFGSSTPDSKAAEK-EDL-ETQPSPSVEK
AASPL-EPKGTI---P-SDVAATEKLAGQSLPEVKLKSAEESRSDSVKPEEGHDLK-EKL
TVLSNVEAVSQLKSN---SGVSSEDYGKHEIPDYSDEMSRNGI-TSAGEKKPLRTQPYSS
TGEQLVMEETKRSIPLHVTENQGHQKP------------EIAPRSKWNISALKEEPS--H
E--------------------------------------------------------QKE
KSLDVVDKVTQQPESASSNFEKP-----------------------IILP-ADSDISLID
RGEERLKKEMPEPSSLKYSEEEVKR----PMQGKDSLESRSCALAEKRELAGKQGVM-AT
LELGENKELERWQVTQEARPFNREEAKPAAELEHGERGREDQEEPARRS-----------
--------------AEGR-NQETRPGSPHA------------------------------
--RAAVPG-EAAVPVSQPSSLVRTPPVTAKPGS---------------------------
-----VLSELVPAAGARKPAAS--------------------------------------
------------------------------------------------------------
---------------------------------------------RRD------------
--------------------------------PPEESEALVERP----GRSGAQPCPAPS
TKP-----PALAPGASAEAEAASKGEA---------------PRAE--------------
---------RPTVHTMQTPNGRPS-----EMPKQSVVSSR----RPSGAVENAPRNAPAP
PAASNYA-RFI-----LSAAPAAASDSPG---------PPA---AEE----AGSAAAGTP
AGL---AEQRPSAFRTASEGCETLNVHAPALVAPLDQEEGEGSPESAPP-------GTR-
PRPDGEAAA-SREAPA-RAP---RGPDGELAALRA-------------------REP--A
DA---PRAEPLQST----RP-EEDYFEKYTLIDYQLSPVPGNLKAVQKLA-A-GGLSKEG
REETASSPDRSQDRVLEREHDLG-AVDESSDGLEKDHSKL-PRPEMQKPLAVQQSLG--G
SAS-KVANRGVGCRSPGMPLFDTDEGVLSRSPMFPTTAKAVDPELLQEPPALAFLYKDLY
EEAVGEK-KEGETASEGDSANSEASFPRRHSDTDDGTGLYFEKNLLKDDM----SVSPED
QGHGLEEKLLGKDYSQQLRAA--GGEVV---GKPGTTSWEKSLEEER-KAAYREREPTDH
----------GKKAPITEEVPVVALK-MSYVVPFEDTPHAVEGGDGP-------------
-------SSQG------NE------VA---------NASPEIHVNVPVQVSFPEE-EFAS
GATYIPETPPGEPNELVSPEPSKE--RAQNSPVQDEYEFAEYLDHEVVSR-GILSEE-LY
SETTQEDVL-SQGPQSFEHIR--KRESVSEGQQSMSAEQKELGGERMEHGQLAPA-LVTE
KAQKEPRTPQIDSYCYTCKSLISATDKVFDTHRDHEISPLDTAISAIKVQLAEFLESLQE
KSLRIEGFVSEIESFFNTIEENCSKNEKRLEEQNEEMMRKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLETIARDAEELDE--AVFLT----SFE--------EINER
LLTAMDRTASLEHMPAAFSLFEHYDDSSARSDQ-VLKQVAVPQPPRLEPQEPNSATSTT-
-LAVYWSMNKEDVVDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCVFEDLEPDRCY
QVWVMA----VNFTGCSLPSEREIFRTAPATPLIRAEDCTVCWNTATVRWRPAN--PEAL
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINTFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSNGTVISFVERRRLTEIPSVLGEELPACGQHYWETT
VTECPAYRLGICSSSAVR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VQVT
ERPARVGILLDYNNQRLLFINAESGQLLFIVRHRFSEAVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------DGDDEATRELETEEESE----GEEDET----AAESEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWEINSSRSSTPWASEESQTSGVCS
QEGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKGSPLTSASQILTTEKEKSYT---GVYDKARK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKR-
----------SESLT---------SMFSYEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QRIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPS-TPATVF--LRTAKEECELASPGTAASENDSSVSPSFTNEVKKED
VCSAHHSIS------LEA-------ALPGLAASTQDG----LDSDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIETSLPVAATPEPEDSNLVE-EETIELDYPASPLVSKKPFPPRM-SPEVEH------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYLAP----------QDLNHELEK----RES------------------
----------------ESVSPSDVEAIAEHAVLS---------------EEENEELEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSLLFSTVTPEHMILSGDEASES-----GHYTPDSTSAS--------------EYSVPSQ
ATKESL--KKAIDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTP---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSECFTSDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKGI------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SEHTVL-----SEDIG
PASPDS-VVASEHS-FPP--------HTTKMTSECQAPPL-----SATPSEYVVLSDEET
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCV
SEADEEDI-GSTAA---TPV-SEQFG--SSSKQKSETFPLMSP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPPHLT-------
--------S---EVKKGEREAS-SSVTAIPA--SLPAQSSIVKEETKPASP---HAVLPD
SV-------------------PAIKKEQEPTAALTLE---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHGS------QD---QKMEPQPPN--
--VTGSEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKSKLVLNVTS--ELEQRKLSENEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSALS--EEVKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVDH-PFLTKVGK-------G
DLGSGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-SASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKAGLSVIKTS-SQ------------------YSDESEEARVE------DKQGL
SCSTVRDSERLVSSQKKSLVSTSEVLGPEHELSLSLWGEIKKEETELPSSQNVSAASKHI
IPKGKDEEIASSSPELENL-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDVALA
E-----LSLEPEKKDKPHQPLELPN---AGSEFASGLGKQSGSIGTKQAKSPITETGDSV
LEKGPTELRSRE-GKEENREFYA--FAIM-PTTSELSSLLREESQNEEIKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPAHFKKGGNQEIGPLPPNGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLLVEQKKTKK----ALHSDQTVKLPD
VS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEKLKL-AEEP
KSLVLAGNVERNIAEEKEIHSLMESESLLLEKANTEFSWPSKE-DSQENIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVRTAHFLAEGVEPAL-GN---EKEGH-RSTPPFSGEKPLEE
SKMVPLKVIDDADE-----EKKPAPEV-KIPTQRTP-ISSLHA--KEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKRKIGISSFKSWMSSLFFGSSTQDSKVAEQ-EDL-ETLPSPSVEK
AVTVI-EPEGTI---P-TNFNVAEKQADRSLSEVKLKTADESRGTLVKSDEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEMNINSVVTSADGEKHLEIQPYSL
ISEKLIMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNLASKNI------------TKESEKSESIILPVEESKGSLVD
LSEDRLKKEMQSPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNKIGKTQITHGSRSIELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEEKKKQEHQPYSVNVAESMIKESGI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLSEAHPEIREAKAVATQPHPLEESKVLVEKTKTFLP--------VALSCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMPDHSEEKEQ-F
RESELSKGGSVDITKESMKQG----------FPTKESERTLAYPFDETKSSETLPYLLSS
VKP-----QTLVSGASPEINAVKKQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTF-----DVPKQSVLVSK----HHLEAVEDTRVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDSDEKVTSLKEKSKQKETR---------HTEEKTST
DSETGDLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEDKLSEEV
TEEAISFPVSSVESPLEHEYDLV-KLDESFYGLEKDHDIL-SHPETQKSL-----AD--R
SVS-KDVKRDVDSKSPGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYQDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQLIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVGH
VETLGNIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPQVNLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILGPPEPSEE--RLRNSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAGQKELGSERKEENQLSSE-LVTE
KTQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKKLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----VSL--------YSPDR
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-RFSDQDEEGKTKQQCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASGESQTSGVCS
PEGSTVVPSPPGNVSFIVDEVKKVRKGTHK--SKHGSPS--LRRKGKKKRNSFESQEDVS
ANKKSNTLFSESRVQKNEKEKSSV---GIYDKMKK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVAYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
SNHDSNIVPQRGKL-----VTQSIKDD----------------NVKELSPPWRSALAKE-
----------SKTLT---------SIFGHEDQ-KKIHADSPLTAA--SATK---------
-----------------HTVSFYSSNDTAE---GEIQFSPPQSV----------PQWPGD
KPKTHDMEPSSFVPD-LSANVL--VETTKKEFEPDSQV-TTSEDDSSVSPSLVDEVKKEE
VYSADHSIS------LEAE-EFLEAGSPGLEASTEES----FSIEKDQPYPTSPER----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------AEPVSE------------
--QLTFS-----------YPSV-------------NGEKEENMPEPSFSLSEPLVLEEPE
KEDTETSLPLAAAPESEDSNLPE-EGIIDLDHPESPFVSEKPFPPHL-APEVEQ------
------------------------------------------------------------
---------------EEEETILPPVTTS-------------TPEHVVVSEEERQ----EN
ESVSTDSAFVSEYSGP----------QDVNHELER----REF------------------
----------------EPVSPSNVTAISEHAVLS---------------EEENEEFELYS
PALASESEH--------------------------------------SFPPSTIEKTSES
QSPSFSIATSVHTVLSEEEVSES-----QCYTPDSLPAS--------------EYSTPSH
ATEESL--EKTVDHKSPLKP--KGVSEDMILSEEKKKDIESYTP---TVSSVSEDFLPPY
TNE-APEPNSPLLSA-ATSEHTVLSEEED-IRSEHFTPDSTLVTKYVVPPNTTHESQKKI
IDDVSQFKSKGVSEHNILSEEE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------EEDIG
LYSPDV-ASVSEHS-LPL--------YTIDMTSECQSPAL-----STTTSEHAVLSE-ES
V-----EMERYTPSSI---------TAS-EFSVPPYATQESKMDEIVHRSPLNLK-----
------------------------------------------------------------
----GAPSPVNLSEEE--QEDIGPFSPDSAFASEFSFPPYAPQEAEKREFECDSPICLTS
PSEHTILSDDDTEEVELFSPDSAS--QVSIPPYRISETK-NGIEPDSLLTAMSASRYSHF
SETDEEDL-GSTAA---TPV-PEHVS--SSKKQKAEPSPWIFA--PEDLSLPPATN--KT
EKAEIKPDAQTTSKSVSEYLILAQK-------QKTQPSF-EAESEDSILLCLT-------
--------S---ESEKGDIKVN-SSVAATPV--SLPAKSS--MEETEHVLPASQYSVSPD
SD-------------------HAIKKEQEPKESLIPK---------ASDEQM--------
-ALSKVR---------------REESVPNSPAAIAHVP------QD---QKMEPLTPN--
--VPRSGMKYSVVSHL-VD-----------------------------------------
-------------------EPKKDDKPNLAPTVTS--ELEQKM-AKNEP---EVIKPHSS
LKETSLSGP----------------------------EVLS----------AVEMEAKHD
SKITITP----VVPHSASSVVEKEVE---------------------------------H
DLPA--------PAFSALP--EEIKKVIESTSSRSSIS-IAK---------HDS------
------------------------------------------------------------
---------------------------------------SLSKLAKEEIPTDI-------
-----------------------------------PVTIPGEH-PVLTKLGN-------D
ELANDLP----------------LL--VTSIDVHSVPKEEEKPAI---------------
---KG-ISFPIETTASSHSGW--SETE-----KENK-------FDSPPTVLSISEHSILS
KVETEEIKPGLPITKASSSE------------------HSDVPKEAMVE------NAQGL
CFSKGLDSEH--VSQKKNSVSASEVVGPEHLLSLNLGGEIKKKDTQPPLSQNVSLAPKHT
VPEDKNEEIANS-SKIENLTSEDLTPTLLILTDK-KKWAMETTSTDQGDYLSEKQGLALT
E-----LSLESEKKDKPHQVLELPS---TDSEFISDLGRLSRPIDKKQVKSLKSETRDSV
SEKSIGEFTNRE-EKQENRELNV--STAL-PEMFEFSSCLREEPQNQEMKPFFPEVVSLG
AKEESPSLVKGENPEELQPTTFSLKGLSEEFNHSANFKKGGKQEIGPLQPAGNLKAQVMG
DILTKPNEETNQPN--SFHVPQSITEPSKITSSDLHVEQKKPEI----LVYSDKVAKLPD
IS-----ISFDDKQDLGIKQFSSMKENLPLEESKSFMTSEPTDIKETKRKESFIYPKD-E
NLLLEKPERDLASHEEERTLGSEQLDSSGS--SNLMTGQFPFAL----------------
-SDKDHIYEIREQVPPHSAEESHLSLQEPMSTLDSSSSNVETPSIQTYSSDEIKLTKELK
SFPVPVGNV----AVEKQIHSFIGSESLILEKENREFSMPCKE--SQEEIKLSPENTLR-
KPAFGSVVEQVKSETIPSSTTAAQFLAEVIETAS-DS---KKEAH-RSTPPLPVEKPLVE
SKMAWSKVIEDADE-----GGKPALEG-QIPTQEKP-LSSIQA-NKEPLSPELPEVTQRL
PKQPKTV-ETCLSEEKGKKGISSFTSWMSSLFFGSSIPDNKVTEK-ENL-KPQSIPSVEK
AVTMIETKSMTL---A-VSDSATEKPVDHPLPEAKLRSADESRAALVKPGGSQDFK-EKA
TILSNIEVLQQPKSN---SEVSTEDYGKKNTLSSSEEMDINSEVTSAGGEEHLDVQTYST
TVEKSVMEEVKSVVPFHVTDIKRSQKP------------AISPPSKWNISVLKEEPQ--S
DQ-----------------------------------------------------KDKSL
FSFDAIDKVPQHPGSTSSNFSSKNI------------TKEPEKPGSIILPMEESKDNLID
HGEDG-----------QISEEEIKLMSVSPAERNENLETRTYSLTEKKVLAEKQGIV-AP
LELRDNNEIEKAQITHGSKLIELEESKAAAILQLF-QN-EDHKERSKIIVGSE----KEK
GE---EKERWSHVFSEENKQQEIQPYSVNVSMSVAEKSDT------------------S-
--LSCSLG-E-----NQPFSLAKATSIIEKTQT---------------------------
-----MLSETHPEIRETKARGTGPHPLEESTFLEEKSKTFIP--------VDLPSRDELD
SYFLPKEDNLALEK----------------------------------------------
--------------------------------------------SSRDMVGLNEEKRQ-F
TVSEPSIGGSMDITKESMKQG----------SPSKESERTLGHPFDTAKSLETPPHLLSS
VKP-----QTLVSGESTEIITTKKQEMPWSEL-----------ISD--------------
---------RHSVHTVQTSKDHTSEEHTSDILEQSVFVSK----HHLETVDDAYVNEPHS
SASSNYT-QFI-----TNASTINVDKTVFTKEISKDPEDTYTKDEEF-------TVTSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFISSVDQEESEWMQDKLEYLEEKVSLKTM-
PFHDNSEAVACHKTLK-TKL---EDSDENVTLLKE-NKKRETH---------KTKEEVSV
DSKTGELAFIEPTM----PS-EEDYFEKYTLIDYNISPDLERLKPPQKLN-IEEDLSQQV
TEAAISFPEGSEDSVPEHEYDLV-KLDETFYGLEKDYSKL-SQPETQKSLTIQISSD--R
DAP-KVLNRDVDSKSPGMPLFGAEEGVLSRTQIFPTTAKAINPELLEEPPALAFLYKDLY
EEAVGEK-KEGETASEGDSVNSEASFPSRNSDTDDGTGMYFEKYVLKDDILHDTSVTQKD
QGQSLEEKPVSKDDSYQPVAA--EGEIW---GRFGTIWGERSLEEEQ-KTIYREGESVDH
VETLDNVA-RQRKAPITEEVRMVTQK-ISYAVPFEDTNNVLERVDVT-------------
-------EVQG------NE------AG---------NASPEVNLNVPVQVSFPEE-EFVP
GATYVQETVQEEPEKMISPEPSED--RLRNSPVQDDYEFAESLNYEVVTQ-DLLSEE-LC
SESTPEDAL-SQGKASFEYIS--ENEFMREVEQSMSAEQRELESERTEQDQLSLA-LVAE
KAQKEPKKSQIDTYCYTCKSPISAIDKIFGAHKDHEVSTLDMAINAIKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKKLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EYLHDQMVHFLQSMDMAKDTLETIVREAEELDE--TVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSTKSDQ-MLKQVAAPGPEVQVYRVLSSQSMTT-
-ICRHTHQTKEKPKCQFLIKIIRLVQREKCL--NDLVEEYRVTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPAS--LEAT
ETYTLEYCRQHSPEG-EGLRSFSGIRGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTRAIGTRFLLLRETAHPALQISSNGTTISFAERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAVQ-AGTLGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
EDPARVGILLDYNHQRLLFINAQSGQLLFIIRHRFSEGVHPAFALEKPGKCTLHLGIEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
QEGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LHRKGNKKRNSFESQ-DVP
TNKKGSPLTSASQILTPGKEKSYT---GVYDKARK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKA-
----------SESLT---------SMFSYEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPLSVTPS-TPATVF--LRTAKEECELASPGTAVSENDSSVSPSFTNEVKKED
VCSAHHSIS------LEA-------ALPGLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIETSLPVAATPEPEDSNLVE--EIIELDYPASPLVSKKPFPPRM-SPEVEH------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----RES------------------
----------------EPVSPSNVEAIAELAVLS---------------EEENEEFEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSPLFSTVTPEHMILSGDEASES-----GRYTPDSTSAS--------------ECSVPSQ
ATKESL--KKAIDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTP---AVTSAAEPSLSPS
TTERTSECQSPLPST-ATSEHVVPSEGED-LGSECFTSDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKGI------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SEHTVLSVE-GKEDIG
PSSPDS-VVASEHS-FPP--------HTTEMTSECQVPPL-----SATPSEYVVLSDEET
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFASEFSFPPYATQEAEKREFECDSPVCLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSIAA---TPV-SEQFS--SSPKQKSETFPLMSP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSASVSEYLILAQK-------QKTQAYL-EPESEVLIPPHLT-------
--------S---EVKKGEREAS-SSVTAIPV--SLPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLE---------AADEQM--------
-ALSKVR---------------NEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--VTGSEMKYSLLPDV-VD-----------------------------------------
-------------------EPKMGVKPKLVLNVTS--ELEQRKLSENEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKIITTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSALS--EEIKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVDH-PFLTKVGK-------G
ELGSGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-SASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKVGLSVIKTSSSQ------------------YSDESEEARVE------DKQGL
SCSTVRDSERLVSSQKKSLVSTLEVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENL-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDVALS
E-----LSLEPEKKDKPHQPLELPN---AGSEFASGLGRQSGSIGTKQAKSPITEIGDSV
LEKGPAELRSRE-GKEENRELYA--SATM-PTTSELSSLLREESENEEIKPFSPKIISLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DIVAKLSEETGHPD--SCQLLQSVTEPSKIALSDLLVEQKKTEK----ALHSDQTVKLPD
IS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIVGSVQLDSSVS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLLSQEAVSALDTSSSNVETLSCKSYSSEELKL-AEEP
KSLVLAGDVERNIAEEKEIHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVRTDHFLAEGVEPAL-GN---KKEAH-RSTPPFSGEKPLEE
SKMVPLKVIDDADE-----EKKPAPEV-KIPTQRTP-ISSLHA--KEPQSPESPEATEKP
LTQPKVA-KPDLPQEKGKKGISSFKSWISSLFFGSSTPDSKVAEQ-EDL-ETLPSPSVEK
AVTVI-EPEGTI---P-TNFNVAEKQADRSLSEVKLETADESRGTLVKSDEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEMNINSVVTSADGENHVEIQPYSL
ISEKLIMEEAKTIVPLNVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKSESTILPVEESKGSLVD
LSEDRLKKEMQSPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNEIGKTQITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEEKKKQEHQPYSVNVAESMIKESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLSEAHPEIREAKVVATQPHPLEESKVLVEKTKTFLP--------VALSCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------STRDMPDHSEEKEQ-F
RESELSKGGSVDITKESMKQG----------FPTKESERTLAYPFDETKSSETPPYLLSS
VKP-----QTLVSGASPEINAVKKQEMPQSEL-----------TPE--------------
---------RHTVHIIQTSKDDTF-----DVPKQSVLVSK----HHLEAVEDTRVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDSDEKVASLKE-SKQKETC---------HTEEKTST
DSETGDLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQRAPQKLN-VEDKLSEEV
TEEAISFPVSSVESSLEHEYDLV-KLDESFYGLEKDHDIL-SHPETQRSLGIQKSAD--R
NVS-KDVKRDADSKSPGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEEETASEDDSVNSEASFPSRNSDTDEGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKFGTICGEKSLE-EQ-KGVYGEGESVGH
VETLGNIA-MQKKAPIREDIRVTTQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPQVNLNVPVQVSFPEE-EFAS
GATHIQETPLEEPKILGPPEPSEE--RLRNSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAEQKELGSERKEENQLSSE-LVTE
KTQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDIAISAVKVQLAEFLENLQE
KSLRIEAFISEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQNFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVVDSFQVYCMEEPQDDQEL--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINVESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-RLSDQDEEGKTKEKCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
LEGSTI-NSTAGNVSFIVDEVKKARKRTSK--SKHGSPS--LRRKGNKKRNSFETQ-DVP
ANKKDSPLISESQVLNTQNEKLSS---GSYDTMRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASVSLEPDM
GNRDSNIVSKTGKL-----VGQSIEDD----------------KGKELTSPWRGALSKG-
----------SKSHT---------SLFSREDQ-KKIYPDSSLKAA--SAAK---------
-----------------HTDSSYRSNDTAE----ETQRSPPQSV----------PQQPGV
EAKPHEMEPSSLMPD-TSATAF--LETAKEKFEPDSQEIVPSEPESLVSPPFMDEVKKED
VYSTDHSVS------PEAEKDSLETGAPGLAASIQED----IGPEREELDLTSPERAE--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------PVSE------------
--QLTSP-----------QLDV-------------KGEKEENVPEPPISLSEHLVSE---
KEEIETSVPIAATPEPEDSHLVE-EEIIELDYPESPSVSEKPLPPHL-APEVEQ------
------------------------------------------------------------
---------------KEEEPILPSLTTS-------------TPEHVALSEEEIE----EN
ESVSTDSAFVSEHSVP----------QDMNHELEK----QEV------------------
----------------EPVSQSIVKATSEHAVLS---------------EEENEEFEPYS
---ASASEH--------------------------------------SLSPSITEKTSEC
QSPLFSTV-------SGEEAAES-----GHYTPDSTSAS--------------EYSIPSQ
ATKESL--K-NIDHKFPLES--KGVSEHMILSEEEKEDTGLYSP---DVASVAEHSLPPS
TAEVTSEYQAPPLSA-TPSEHVVLS-EEE-LGNEHFTPDSTLNSQYIVPPNVTQEIPKKI
IDDASLLKSKGVSEHITLSEEE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDTG
LYSPDV-ASVAEHS-LPP--------STTEMPSEYQAPPL-----SATPSEHVIPSEEET
V-----GMDRYTPSS-------------------------SQEEEIVHRSPLNLK-----
------------------------------------------------------------
----GVSSPVNYSEEE--QEDVEPFSPDSAFVSEFSFPPYATQETERRELECESPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSVPPYRIPETKKNEIEPDSLLPAVSASGYSCF
SEADEEEI-ESTAA---TPV-PEHLS--SSQKQQAEPSPPMSA--SGELSLPNKAE----
-----EADAQTFSTSVSEYLISLQK-------KVTQAFL-EPESEDLIPPHLT-------
--------S---ELEKGEIKTS-SSVAATPV--SVPAESPTVKEETKPVSPSSQYSVSPD
SV-------------------HALKKEQETKALLTPK---------AANEQM--------
-ALFKVK--------------SKEEILPDSQEAAAHVS------QD---QEMEPQPPN--
--VPGSGMKFSTLSDL-VD-----------------------------------------
-------------------EPKKDVKFNLAPTVTS--ELEQRIFSENEP---EVIKPYSP
LKEPPLSGP----------------------------ERLS----------AVKTEVKHD
SKIIGVP----RVPRSASPGVEKEVE---------------------------------P
GPSA-----------PEFS--EERKKEIEPSSSITTTS-LAK---------HDS------
------------------------------------------------------------
---------------------------------------NLTKLAKEEIPTEL-------
-----------------------------------PLTTPIEH-SVLT-VGK-------R
ELESGLP----------------PS--VTSMDEQLLLIDEGKIAI---------------
---KA-SSPHIETVASKHPTW--SEAE-----KEIK-------LDSPPSISSISEHTILS
KVETEEVKPGLPVTKTLSSQ------------------HADVSKDARVE------NKQGL
SFSTVLDSEPLALPQKKNSVSASEVSG----LSVNLGGEIKKKEAELPFSQNVSPAPKHE
VPKGKTEKMASSSPKLETLVSEDLAPTLPTVSDDKSKQAMDTSSTAQGDFLSEKQGLALA
E-----LSLEPVKKDKPRQISELPN---AG-----GLGRQSGSMDSKQIKSPMTETGGSV
LGKGLAELRSRG--EEEDRELHV--STTV-PEISKVSSYLKEKPPNQEIKSVSPNVVSLG
SKEAFTSLVEGDNPEELQPYTFTLEGLSKELSHSVDFKKGEKQEISSLLPTGNLKAQVTG
DAVTTLKEETDQTH--SFPVSQSIMKPSKMVSSDRLMEQEKPEN----TLYSDQAVKVPD
VS-----TSFVAKQDLGIKQLAVMKENLPLEESKSFLTTECADVKETQMREALISPED-E
NLILEKPERDLASHREERVLGSVQLGSSGS--TDLETGQPKAAL----------------
-SSKDRAYETGKQILPHSAEEPHLSLQEPVTTHDIPSGNVEILSTKTS-SEEIKL-VPQT
KSFFPTGNVERNEAEGKQVFSFTRSESSVLEKANTEFSRPCKD--SQEEVKLPSERILQ-
KPVSGPSMEQVKSETIPSRAKAAPFLAEDAEPVV-GN---KKEAL-RSVSPLPGEKQLEE
SKMDQAKVVDDTNE-----RGIPTSGM-KISTQIKT---SILE-NKEPQPPESPEVTQKL
PEQPKAV-KPGHSEEKKKKGISSFTSWMSNLFFRSSTPDNKVAEK-EDL-ETQPSPSIEK
AATVI-EPKGTA---P-ADLNATEKPAGQLLPEAKLITAEESRGTLVKSEEGQDFK-EKP
TLSSNVEVLQQPESN---FEVSSEDRGKK-------EMDLNSVVTSVDSEEHFGIQSYSP
MGEKSIMEEAKN-----VPDNKRAQKP------------EISSPSKWNISILKEEPR--S
DQ-----------------------------------------------------KENSL
FSSDAVDKVTQQPKSISSSFTSENT-------------RESEKPELIILP-ENSKGSLIN
LGEDRLTKEMPKPTSLKISEEEVKLRSVSPTEEKDNLEIRSYSLAEKKVLAEKQETV-TP
LELRYNNEIEETPITHGSPHIKLEESKAAAVLQQVCQN-EDYKERHKITEEEK-------
G---KEKVKQLQAFSEGKKQQEIQPYSVNIARTMPEKSDD------------------S-
--LSRSLG-E-----TQPFSLVKTTLTIEKSET---------------------------
-----MISETHPEIRETKVVGTQPSLLEESKVLVEKTKTFPP--------VELPYRDELD
GHSFPKEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMASHNEKKGQ-V
TVSELSKGGSVDSTKDNIKQG----------S-----------PSKESKSLETPPSLLSS
VKP-----QTLVSEASPEISTIKNQEISTEKK--------QELTPD--------------
---------RHTVHTIQTSKVQTS-----EMSKQPVLVSK----HHLGAVGAARVNEPHS
PASSNYA-EFI-----RNASTTNANKIS------REPE------EEF-------TMTSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQDKLEYLEEKASLKTL-
PFPGDSEAVACHKTLK-SKL----DSDKKVTSLKE-NKQKETH---------ETKEEIAT
DSETGDLAFNQPTV----PG-EEDYFEKYTLIDYNISPDTEIQKASGKLN-VEVKLSKEV
TEEAVSFPESSEESALEHEYDLV-KLDESFYGLEKDYSKL-SHSETQKSVVIQKSAD--R
DSS-KSTNRDVDSKSPGMPLFDTDEGVLSRTPIFPTTAKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEGETASEGDSVNSEASFPSKNSDTDDGTGIYFEKYILKDDILHDTSVMEKD
QDQGLEGKSVGKDDSYQLIAA--EREIG---ARFTTIWGERSLEEEQ-KASYREGEPVGH
VETLDNVD-TQRKAPITEEVKVVTQK-ISYAIPFEDTPHVLESRDET-------------
-------STQG------NE------AA---------NANPEVILNVPVQVSFPEE-EFTS
GATCVQETLQVEPQIMVLPEPSED--RLRSSPVQDEYEFAESLNYEVVTQ-DTLSEE-LY
SESMPEDVL-SQGKESFEHIS--GNEFVSEVEQSMSSEQNELGRERTE-DQLSSE-LVTE
KEQKEAKKSQIDTYCYTCKSPISAVDKIFGTHKDHEVSTLDTAISVVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKKLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVRFLQSMDAAKDTLETIVREAEELDE--TVFLS----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSINKEDVIDSFQVYCMEEPQDDQEV--NDLVEEYRVTVKESYCIFEDLEPDRYY
QVWVMA----VNFTGCSLP SERAIFRTA PSTPVIRAEDCTVCWNTATIRWQPVN--PEAT
ETYTLEYCRQHSPEG-EGLRSYSGIKGLQLKVNLQPNDNYFFYVRAINTFGTSEQ SEAAL
ISTRAIGTRFRLLRETAHPALQISSNGTVISFAERRRLTEIPSVLGEELPA CGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNHQRLLFINAESGQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASSESN-----
--HTGESFLGS-------DGDEEATRELETEEETE----VEGDET----AAESEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKPRKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKDSPLTSASQVLTMEKEK--S---GIYDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDANTVYKTRKL-----VAQSIED-----------------KVKEVVPPWRGTLSKG-
----------SESLP---------SMFSHKDQ-KKIFPDSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QELQLRPSQSV----------PQQPED
EAKPCEVEPP------SPATAF--LRTAKEECEVASQGTAASASDSSVSPSFANEVKKED
VYSAHHSIS------VEA-------DSPGLAATTQED----LDPDQEHPDMTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------QRAEPASA------------
--KLTPA-----------QPTV-------------KGEKEENVLEPSISLSEPLMLEEPQ
EEEIETSLPIAATPEPEDSNLVE-EETIELDYPESPLVSEKPFPPCM-SPEVEH------
------------------------------------------------------------
---------------KEEELILPLLI-S-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYSVL----------QDLNQELEK----REG------------------
----------------EAVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASASES--------------------------------------SLSPFTT-KTSES
QSPLFSTVTPEHMVLSGDEASES-----GRYTPDSTSAS--------------EYSAPSQ
ATKESL--KKIIDHKSPLIS--KDVSEHMIPSEE-KEDTGSFTP---AAASASQPSFSPS
ATKKTSECQSPLTST-AMSEHVVPSERED-LGSERFTPDSKLASKYATPLNATQEPQKKI
IDEASQFKPEGISECTILSEEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIE
LSSPDS-VAASEHS-FPP--------HTTEMTSEHQAPPL-----SATPSERGVLLNEET
V-----ELERYTPSST---------SAS-EFSIPPYATPESQEEEIVHR-SLNVK-----
------------------------------------------------------------
----GASSPVNSSEED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPMCLTS
PSEHTIFSDEDTEEAELFSPDSAS--QVSIPPFRIPEREKNDFEPDSLLTAVSVSGYSCF
PGADEEDI-GSTAA---TPV-PELYS--SSQKQKAETFPSVSP--LEDLSLPPSTD--KS
GKAETKPEIPATSASVSEYLILAQK-------QKTQASL-EPKSEDLIPSHLT-------
--------S---EVEKGEREAS-SSVAAIPA--SLLVQSSVVKEETKPASP---HSVSPD
SV-------------------PAIKKEQEPTVALTLK---------AVDEQM--------
-ALPKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--VPGSETKYSILPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQGKLSKNEP---EVIKPYSP
LKETSLSGP----------------------------GVLP----------AVKMEMKHD
SKIMSTP----SVLDSASSGVDKQVE---------------------------------H
GLPA--------LAFSALS--EEINKELEPGSSTTTAI-VAK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKLGKEEIPTDL-------
-----------------------------------SLVTSVDR-PVLTKVGK-------G
ELESGLP----------------PL--VTSSDEHSVL-AEEDKVA---------------
---VK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EAEAKGVKAGLPIIKTSSSQ------------------HSDESEEGRVE------DKQGL
SYSIVRDSERLVSSQKKSLVSTSEVLGPENELSLGLEGEIKKEETKLPSSQNVSPAPKHI
VPKGRDEEIASSPPELENL-ASGLAPAVLLLSDDKNKHAVEVSSSAQGDFPSEKQDVALA
Q-----LSLEPEKKDKPHQPSELPN---AGSEFASGLGRQSGSIGTKQAKSPITETGDSV
LEKGLAKLRSRE-RKEENREFYA--SATM-PVISELSSLLREESQNEEIKSFSPKIVSLE
SKETPTSLAEGDNPEEFQPFSFSLKGLSEELSHSADFKKGENQEIGPLPSPGNLKAQVMG
DVAAKLSEETGHPD--SSQVLQSITEPSKIAPSDLLVEQKKTEK----ALHSDQTIKLPD
IS-----TSFAGKQDLDIKQFSFMKENLPLEQSKSFMTAKPVDIKETRREEFFISPKD-E
NWMLGKPEHM-AYQHEERKAGSVQLDSSGS--NELRPGQLQAAV----------------
-PSKDLTCEVRKQVLPDSAEESHLSSQEPVSALDTSSGNVESLSSQSYSSEEVKL-AEEP
KSLVLAGNVERNVPEKKESHSFTESESLLLEKANTEFSCPSKE-DSQEKVKLPPERFLQ-
KSVSGPSVEQVKSETIPSSVKTAHFLAEGVEPAL-GN---EKESH-RCTPPFPGEKPLEE
SKMVQSKVINDADE-----GKKPEPEV-KIPTQRKP-ISSIDA--KEPQPLESPEVTQKS
PTQPKVA-KPDLPEEKGKKGLSSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPSPSVET
AVTVI-EPEGTI---P-ANFNVAEKPADHSLSEVKFKTVDESRGTLVKFDEGQNVK-EKS
TILSNLEDLQQPKSI---FEVSREDYGKKEISGDSEEMSINSVVTSADGEKHLGIQPYSL
ISEKLVMEEAKTVVPLHVTHSKGVQKP------------AISPPSNWNISIFKEQPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKLASSNFASKNI------------TKESEKPESIILPVEESKGSLID
LSEDRLKKEMQKPTSLKIFEEETKLRSISPTK-KDNLENRSDTFVEKKVMAEKQDSV-VP
LELRDSNEIGKTQITRGSRSVEQEESKVNAMPQHFYQN-EDYSERPKIVVGSE----KEK
GE---EKENQVYVLSEGKKQQKHQPYSVNVAESMTEKSDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSEA---------------------------
-----MLSEAHSEVRETKAVGTQPHPLEESKVLVEKTKTFLP--------LDLSCHDEIK
NHSLSQEGNLVLE-----------------------------------------------
-------------------------------------------KSNRDMPDHNEEKEQ-F
KDSELLKGGSVDITKESMKQG----------FPSKESERTLAHPFDETRSSETPPYFLSS
VKP-----QTLASRASPEINAVKKQEMSRSEL-----------APE--------------
---------RHTVHTIQTSKDHTS-----DVPKQSVLVSK----HQLEAVEDTGVKEPLS
SVKSNYA-QFI-----SNASASNADTMVSAKEMSKETEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKLSFKTIP
PLPDNSEAVPCHETLK-SRL---EDSDEKVIPLKE-NKQKETH---------KAKEEIST
DSETGDLSFIQATI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEV
TEEMISFPVSSVESTLEHEYDLV-KLDESFYGPEKDHDVL-SHPETQKFLGIQKSAD--R
NVS-KDIKRDVDSKSLGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEEETVSECDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTQKD
RDQGLEEKRVGKDDSYQPIAA--EGENW---GKFGTIHKEKSLE-EQ-KAVYGEGESVGH
VEILGNMA-MQKKAPITEEVRVATQK-ISYAVPFEDTNHVLERTDEA-------------
-------GSED------NE------AG---------NANSEVNLNVPVQVSFPEE-EFAS
GASHVQETPLEELKILVPPEPSEE--RLRNSPVQDEYEFAESLHYEVVPQ-GILSEE-LS
SESTPEDVL-SQGKESFEHIS--ENEFVSEAEQSTSAEQKELGSERKEQDRLSSE-FVTE
KAQKEPKKSQIDTYCYTCKSPISATDKVFGTHKDHEVSTLDTAISAVKVQLADFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVTVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPAT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGTLGQGETSWCMHCSEPQR---YTFFYSGIMSD---VHVT
ERPARVGILLDYNNQRLVFINAESGQLLFVIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-RLSDQDEEGKTKQKCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
LEGSTM-SSPPGNVSFIVDEVKKVRRRTPK--SKRGSPS--LRRKGNKKRNSLESQ-GVP
ANTKDNPLISESQGLSTQKEKSST---GIYDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVRYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDM
SNRDSNIVSQTGKL-----VGQSIEDD----------------KIKELASPWKAAFSKG-
----------SEFLT---------SSFSHEDE-KKIYVDSPLKAT--STTK---------
-----------------HTVSSYASNDTAE---QEIQLSPPQSV----------PQQPGN
EAKLHEMEPSSLTPD-TPTTGF--LETAKEEVEPDSQEIMTLEHDSSVLPPIVDEVKKED
VYSVDQSIS------LEAEKDSSETGAPGLPASIEED----FGPETEELDLTSP------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------ERAETVSE------------
--QQTPP-----------HLDV-------------KGMGEEHVPEPSTSLSEPLVLEEPE
K-EVKTSLPIAATAEPEDSNLVE-EEIIELEYPESPSISKKAFSPYL-AAEVEQ------
------------------------------------------------------------
---------------KEAEILLPSLKTS-------------TPEHFASSEEERE----EN
ESVSTDSAFVSEYSVP----------QDLNHELEK----QEV------------------
----------------EPVSPSTVKGVPEHAIFS---------------EEENGEFEPL-
---ATASEH--------------------------------------SLSPSTTEQTSEC
QSPLFSAAFSEPVVLSGEEASES-----GCYTPDSTSAS--------------EYSTLSQ
AAKEPL--MKTIDQKSPLKS--KDVSEHTILSEE-KEDTGPYSL---DVASVSERSLSPS
TTEKTSECQAPLFST-ATLEEAVMAEEED-LGSECFTADSTLTSQSAVPPNAT-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------QDSPKKKIIDDVSPLKSKGVSEHMILPEE-KKEDTG
LYSPNV-ASVSECS-LPP--------STAEQTSEWQAPSF-----AATPSEHVVLSE-ET
A-----EIERYTLSST---------STS-EFSGPPYATLESQEEEIVHRSPLNLK-----
------------------------------------------------------------
----GASSPMNFSEEE---QDIGPFSPDSAFVSEFSFSPYATQETEKREFECDSPICLTS
PSEHTILSDEDTEEVELFSPDSAS--QVSIPPYRFPETKKNEFEHGSLVTAISASGYSCS
SEAGEEDI-VPTAA---TPT-----G--SSQKQQAKPSPLMSA--PEDLSLPSSTS--KR
EITEVEPDAQTISTSVSEYLILTQQ-------QITRPFS-EPESEDLISPYST-------
--------S---ETEKGEIHTS-SSVAATPV--SLPAQSFLVEEDTKPVLRSSQYSVSPD
TV-------------------HALQKEQEAKASLTPK---------AANEQM--------
-ALLKVK--------------SKEEIVPDSQEATAHVS------RD---QEMELQPPN--
--VLGSGMKYSVLPDL-VD-----------------------------------------
-------------------EPKKDVKPNLAPIVTS--ELEQRMLSENEP---EVIKPYSP
LKDTSLSGP----------------------------EILS----------AVKMQVEHD
SEIADTS----RVLHSAPPGVQEEAE---------------------------------H
GPPA--------PE---FS--EEIKEEIEHSYSIMTTS-VTK---------HDS------
------------------------------------------------------------
---------------------------------------SLTKLGKEETPTDL-------
-----------------------------------SLTTPIEH-RVLTKVEK-------S
ELGSGLP----------------PL--VTSIDEHSLL-T---------------------
------------------------EAE-----KEIK-------FDSPARISSLSEHS-LS
RVETEEVKPGLPITEALSSQ------------------HSDVSKEERVE------NEQGL
SFSTVLDSEQLVLSQEKNSVSASEVSGPEHVLLLNQSGEVKKKETELPSSQNMSSVPKHI
VPKDKNEEMESSSPELENLVSADLTL---TPRDDKSKQAVKPSSTAQGDFLSE--NLALA
Q-----LSLEFEKKHKPHQVSELPS---TESEFTLSLGGQDGSVDTKQIKSHITETGDSD
LEKGLTELRSRGEGKEENREHHV--STTVDPEIPEVSSCLREEPQIQEIKSFSPKVVSLG
SKEALTSLVEEDSTEELQPHTFSLKGLSEKSNHLADIKTGEKQEISPLLSTGNLKTQVIG
DIETKLNEETDQPN--SFRVPQSITEPSKIVSSDLV-EQEKPGK----ALHSDQAVQLPD
VS-----MSFADKQDLSVKQFLFMKENLPLEESKSFMTTEHAAVEETQMQEALFVPED-E
SWMLEKPGRDLTSQHEERILGSVELGSSGS--NDLMTGQLKAAL----------------
-LDKDHTCETRKQLLPHSAEEPPLSLQEPVATLTTSSGDIETLSTKTYSSEETKL-APKP
KSLVPTGNVERDEAEEKQIFSFVGSESLMLEKANTESSRPCKEEGSQEEIKLPSERILQ-
KPVSDPTMEQIKSETIPSPTKAAHFLAEDAEPAW-GN---EKEAH-ESISPLPGAKPLKE
AKMIQSKVVDDVNE-----RGKIASEV-KTPTPLKL-LSSMQE-NEEPQPAEPPEVTQKL
PKQPKAA-EPDLSEEKGKKGILSFTSWMSSLFFGSSTPDKKVAE--KDL-ETQPSPSVEK
AVPVT-ESEGTA---S-ADSNATEKPADRLLPETKLKTAEKSRGTLVKSDKGQDFE-EKP
TSLSNIEILQQPKSN---FEVSSENYGKKEILDYSEEMDLNSVVASADGEEHLEIQSYSP
MGEKSTVEEVQNAVPLNITDRKRAQKP------------EISDPSKWNISILKEEPR--S
DQ-----------------------------------------------------KEKLL
FSFDAVDKVPQQPKSASSSFISKNI------------TKESEKPETIILPVEESKHSLID
LGEDRLKKEILKPTSLKTSEEEIKLSSVSPTEEKGDLEIRSYSVAE-KVLAEKQETV-AP
FEFRD-NEIGEAQIAHGSSLIKLEELKAAD-VLQVSQN-EDHKERHTIMKQEK-------
----EEKQKPSHIFSEGKQQQEIQPYSVNVVRSMPEESDI------------------S-
--LSPSLD-E-----IQPFSLIKTISVAEKSET---------------------------
-----MLLEARPEIMETRAVGTQPQPREESEVLVEK---ILP--------VDLPYHDERD
NHSLPKEGNLILEK----------------------------------------------
--------------------------------------------SSRGMASHNEEKGQ-V
TVAEPSKDGSIDTTKESMKQG----------SLSKEPEKILDRPFDETKSLETPPYLLSS
VKS-----QALVSGTSSEINTVKKQEMPWSEL-----------TRD--------------
---------RHTVHTIQTSKDLTS-----EMSKQSVLASK----HHMEVVEHAHVNEPPS
SASSNYA-QFI-----KNASAISAGRTVPAREISKEPEDTYVKDEDF-------TVTSKP
AGL---SEDQKSAFSIISEGCEILNIHASAFISSVDQEESEQMQDKLEYLEEKSSFKTI-
SLHDNSEAVSCHKTLK-NKL---EDSDR-VTSLQE-NKEKEPL---------NTKQEVPT
DSETDDFNFNQPTA----PS-EEDYFEKYTLIDYNISPDPEKQKAPWKLN-VEVELPKDV
TEDTVSFPESSEGSALEHEYDLV-KLDESFYGMEKDYSKL-FHPETQKPLDIQQSAK--R
DAS-ESINRDVDSKSPGMPLFGAEEGVLSRTQIFPTTTKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVSQKD
QGQGLEEIAVGKDDSYQPIAA--EGEIW---GRFGTILGEKSLEEEQ-KATYREGESVCH
VETLDNEA-MQGKAPITEEVTVVTQK-VSYAVPFEDTHHVLERADET-------------
-------SSQN------NE------AA---------SASPEVNLNIPVQVSFPEE-EFSS
GITCVQETLQEEPKIMVPSESSED--RLHGSPVQDEYEFGESLNYEMVAQ-DTLSEE-LY
SESTPEDVL-SQGKESFEHVS--ENEFVSEVEQSMSVEQKELGIEKTEQEQLPSE-SAAE
KEQKEPKKSQIDTYCYTCRSPISAVDQMFDMHKDHEVTTLDTAISAVKVQLAEFLDNLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKKLEEQNEEMMKKVLAQYDEKAQSFEEVKKRKM
EFLHDQMVHFLQSMDTAKDTLESIVREAEELDE--TVFLT----SFE--------EINDR
LLSAMESTASLEKMPAAFSLFEHYDDSSTRSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NDLVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLP SERAIFRTA PSTPVIRAEDCTVCWNMATIRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVKAINAFGASEQ SEAVL
ISTRA-GTRFLLLRETAHPALQISSNGTVISFAERRRLTEIPSVLGEELPA CGQHYWETT
VTDCPAYRLGICSHSAVQ-AGALGQGETSWYMHCSGPQR---YTFFYSGIVSD---VHVT
ERPARVGVLLDYNNQRLLFINAESGQLLSIIRHRFSEGVHPAFALEKPGKCTLHLGIEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFVVDEVKKARKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKDSPLTSASQVLTMEKEK--S---GIYDKTRR----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTRKL-----VAQSIED-----------------KVKEVAPPWRGTLSKG-
----------SESLP---------SVFSHKDQ-KKLYADSPLNAT--SALA---------
-----------------YTVPSYSSSDRAE---QELQLRPSQSV----------PQQPED
EAKPPEVEPP------SPATAF--LRTAKEECEVASQGTAASANDSSVSPSFANEVKKED
VYSAHHSIS------LEA-------ESPGLAASTQEG----LGRDQEHPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------QRAEPVSA------------
--KLTAA-----------QPSV-------------KGEKEENVLEPSISLSEPLTLEEPE
EEEIETSLPMAATPEPEDSDLVE-EEVIELDYPESPLVSKKPFPPRA-SPEVEH------
------------------------------------------------------------
---------------KEEELILPLLT-S-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEFSVP----------QDLNHELEK----REG------------------
----------------EAVSLSNVEAIAEHTVLS---------------EEENEEFEAYS
PVVASASES--------------------------------------SLSLFTT-KTSES
QSPLFSTVTPDHMVLSGDEASES-----GRYTPDSTSAS--------------EYSAPSQ
ATKESL--KKIIDHKSPLIS--KDVSEHMIPSEE-KEDTGSFTP---AVASASEPSLSPS
TTEKTSECQSPLPTT-ATSEHVVPAEGED-LGGERFIPDSKLASKYAAPVNATQESHKKI
IDEPSQFKPKSISECIILSKEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIE
PSSPDS-VATSKHS-LPP--------HTTERTSECQASPL-----SATPSERGVLSDEET
V-----ELEQYTPSFT---------SAS-EFSIPPYATPESQEEEIVHR-SLNLK-----
------------------------------------------------------------
----DASSPMNLS-ED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTIFSDEDTEEAELFSPDSAS--QVSIPPFRIPETEKNDLEPDSLLTAMSASGYSCF
PRADEEDI-GSTAA---TPV-PELFS--SSQKQKAETFPSTSP--LEDLSLPPSTD--KS
QKAETKPEIPATSASVSEFLILAQK-------QKTQASL-ESESEDLIPSHLT-------
--------S---EVEKGEREAS-SSVAAIPT--SLLAQSSVVKEETKPASP---HSVSPD
SV-------------------PAIKKEQEPTAALTLK---------AVDEQM--------
-ALPKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--VPGSETKYSILPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQGKLSKNEP---EVIKPYSP
VKETSSSGS----------------------------EVLP----------AVKMEMKHD
SKITSTP----SVLDSASSGVDKQVE---------------------------------H
GPPA--------LAFSALS--EEINKALEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKLGKKEIPTDS-------
-----------------------------------SLVTPVDR-PVLTQVGK-------G
ELESGLP----------------PL--VTSADEHSVL-VEDDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSVAEHSVLS
EAEAKGVKAGLPIIKTSSSQ------------------H--ESKEGRVE------DKQGL
SYSTVRDFERLVSSQKKNSVSTSEVLGPEHELSCSLEGEVKKEEAKLPSSQNVSPAPTHT
VPKGRDEEIASSPPELENL-ASGLDPTVLFLSEDKNEHAVEVSSSAQGDFLSEKQDVALA
Q-----LSLEPEKKDKPHQPLELPN---AGSEFASGLGRQSGSTGTKQEKSPITETGDSV
LEKGLAKLRSRE-GKEENREFYA--SATV-PTISELSSSLREESQNEEMKSFFPKIVSLE
SKETPASLAEGDNPEEFQPFSFSLKGFSEELSHSADFKKGENQEIGPLPSPENLRAQVMG
DIVAKLSEETGHPD--SSQVLQSVTEPSKIAPSDLLVEQKKTEK----ALHSDQTIKLPD
VS-----TSFAGKQDLDIKQFSFMKENLPLEQLKSFMTAKTVDVKETTREEFFISPKD-E
NWMLGKPEHV-ARQHEERKAGSVPLDSSGS--NELRPGQLQAAV----------------
-SSKDHTCEVRKQVLPDSAEESHLSSQEPGSTLATSGGDVETLSSQSYSTEEVKL-DEEP
KSLVLAGNVERNVPEK-ESHSFMESESLLLEKANTEFSCPSKE-DSQEKIKPPPERFLQ-
KSVSGPSVEQVKSETIPSSVKTAHFLAEGVEPAL-GS---EKEAH-RSTPPFPGEKPLEE
TKMVQSKVIDDADE-----GKKPEPEV-KIAAQRKP-ISSIDT--KEPQPPESPEVTQKP
PTQPKVA-KPDLPEEKGKKGLSSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPSPSVEK
AVTVI-EPEGTI---P-PNLNVAEKPADCSLPEVKCKTADKSRGTSVKFDEGQNVK-EKS
TILSNLEDLQQPKSI---SEVSREDYGKKEISGDSEEMSVNSVVTSADGEKHLGIQPYSL
IGEKLVMEEAKTVVPLHVTHSKGVQKP------------AISPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKPASSNFASKNV------------TKESEEPESIILPVEESKGSLID
LSEDRLKKEMRKPTSLKISEEETKLRSISPTEKKDNLENRSYTLAEKKVMAEKQDSV-VP
LELRDSNEIGKTQITRGSRSTEPEESKVNAMLQHFDQN-EDYGERPQIVVGSE----KEK
GE---EKENHVYVLSEGKKQQKHQPYSVNVAESMTEKSDI------------------S-
--LG-----E-----TQSFSLVKATSLTEKSEA---------------------------
-----MLSEAYSEIRETKAVGTQSHSLEESKVLVEKTKTFLP--------VDLSCHDEIK
NHSLSQEGNLVLE-----------------------------------------------
-------------------------------------------KSSRDMPDHNEEKEQ-F
KESELLKGGSVDITKESMKQG----------FLSKESERTLAHPFDETRSSETPPYLLSS
VKP-----QTLASRASPEINAVKKQEMPRSEL-----------APE--------------
---------RHTVRTIQTSKDHTS-----DVPKQSVLVSK----HQLETVEDTGVEEPVS
SAKSNYA-QFI-----SNASASNADKIVSTKEISKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKLSFKTI-
PLPDNSEAVACHETLK-SRL---EDSDEKVTPLKE-NKQKETH---------KTKEEIST
DSETGDLSFIQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKALQKLN-VEEKLSEEV
TEEMISFPVSSVESTLEHEYDLV-KLDESFYGPEKDHDML-SHQETQKFLGIQKSPD--R
NVS-KDIKRDVDSKSLGMPLFEAEEEVLSRTQIFPTTVKAINPELLEEPPALAYLYKDLY
EEAVGEKKKEEETVSEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTQKD
QDQGLEEKRVGKDDSYQPIAA--EGEMW---GNFGTIR-EKSLE-EQ-KAVYGEGESAGH
VEILGNIA-MQKKALITEEVRVATQK-ISYAVPFEDTRHVLERTDEA-------------
-------GSQG------NE------VG---------NANPEVSLNVPVQVSFPEE-EFAS
GATHVQETPQEGPKVLVPPEPSEE--RLRNSPVQDEYEFAESLHYEVVPQ-GILS-E-LS
SESTPEDIL-SQGKESFEHIS--GNEFEGEAEQSTSAEQKELGSKRKEQDQLSSE-FVTE
KAQKEPKRSQIDTYCYTCKCPISTTDKAFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVTVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPCTPMIRAEDCTVCWNTATIRWRPAT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGTLGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLVFINAESGQLLFVIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

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------------------------MVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
LEGSTM-NSSPGNVSFIVDEVKKVRKRTPR--SKRGSPS--LRRKGNKKRNSFESQ-DVP
ANTKDNLLISESQVLNSQKEKSSS---GVHDKIRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKD--ASISLEPDL
SNRDSNLVSKTGKL-----VAPSIEDD----------------KVKGLASPWRGVLSKR-
----------SESST---------SSFSHEDE-KKIYVDSPLKAT--SATK---------
-----------------HTVSSYASNDTAE---QETQLSPPQLV----------PQQPDD
ETKLREMESSPLTPD-TSTTGF--LGRAKEEFEPDSQEIVTSEHDSSVSPPSVDEVKKED
VYSADHSIS------LEAEKVSRVTGLPGLAASIQED----FGPETEGVDLTST------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------ERAEPVSE------------
--KWSPP-----------HLDV-------------KGVEEENVPEPSISLSEPAVLEESK
-KEIETSLPIATTPESEDSNLVE-EEIIELEYPESPSISEKPFPSYL-APEVEQ------
------------------------------------------------------------
---------------KEEEITLPSLKTS-------------TPEYVASSEEERE----EN
ESVSTDSAFVSEYSVP----------QDLNHEPEK----QEV------------------
----------------EPVSPSTVKGISEHAVFS---------------EEENEEFEPL-
---ASASER--------------------------------------SLSPSTTEKTSEC
QSPLFSAAISEHVVLSGEEASES-----GYYTPDSTSAS--------------EYSTPSQ
ATKESL--KKTIDHKPPLES--TGVSEHVILSEE-KEDTGPYSP---DVASVSEHSLPPS
ITEQTSECQSPLFST-ATLEQAVLS-EED-LGSECFTPDSTLTSQYAVPSNAMQESPKKI
IDVVSPLKSRHVSEHMILSEEK-EDTG-PYSPDVASVSEHSLPPSITEQTSECQSPLFST
A----TLEQEVVSEEDLGSKRFTPDSTLSSQYAVPSNAMQESPKKIIDVVSPLKSRHVSE
HMILSE--EKEDTGPYSPDVASVSEHSLPPSITEQTSECQSPLFSTA-TLEQVVLS-E-E
DLGSECFTPDSTLSSQYAVPSNAMQESP-KKIIDDVSPLKSKGVSEHMILSEE-KKEDTG
LYSPDV-VSVSEHS-LLP--------STTEQTSECQSPPL-----SATPSEHAVLSE-ET
V-----EIERYTPSST---------ATS-EVSVPPYATPESQEEEIIQISPLNLK-----
------------------------------------------------------------
----GVSSPTNFSEEE--QEDIGPFSPDSAFVSEFSFSPYATQEIEKREFECDSPICLTS
PSEHTILSDEDT-EVELFSPDSAS--QVSIPPYRIPETKKNEFEHDSLVTTISASGYSCF
SEAGEEDI-APTAA---TPV-PEHLS--SSQKQQAKPSPSLSA--PEDSSLPPSAN--KR
EITEVQPDAQTISRPVSEYLILAQE-------QITRAFL-EPDSEDLIPSYLT-------
--------S---EMDKGEIQTI-SSVAARPV--SLPEQSFTVKEDTKPVVCSSQYSASPD
SV-------------------HALKEEQELKTSLTPK---------AANEQM--------
-ALLKVK--------------SKEEIVPDSQEATAHVS------RD---QEMEPQPPN--
--VLGSGMKYSVLPDL-VD-----------------------------------------
-------------------EPKKDVKPNLAPTVTS--ELEQRMLSENER---EVIKPYSP
LKDTSLSRP----------------------------EILS----------AVKTQVKHD
SKITDTS----RVLHSAPPGVQKGTE---------------------------------H
EPPA--------PE---FP--EEIKKEIEPSCSLTTTS-VTK---------HDS------
------------------------------------------------------------
---------------------------------------GLTKLAKEETPTDF-------
-----------------------------------SFTTPLEH-PVLTKVEK-------S
ELGSDLP----------------LL--VTSTDEHPLL-KEEK-VA---------------
---LK-ISSSTETATSERPAW--SEAE-----KEIR-------LDSPAGISSVPVHY-LS
KVETEEVKPGLPITKALSCQ------------------HSDVTKEERVE------NEQGV
SFSTVLDSEQLVLPEKKNSLSASEVSGPEHVLLLNEGSEVKEKETKLFSSQNMSPAPKQT
APECKNEEIK-SSPALENLASEDLTP---TLGDDKNKEAEEPSSTAWGNFPSERQDLVLA
E-----LSLEPEKKDKPYQVSELLS---TGSEVIHSLGGQDGSIDTKHIKSPITETGDSV
LEKSLTELRSRGEGKEENRERHV--SATVDPEIPEVSSYLREEPQIQELKSFSPKVVSLG
SKEALDPLVEGDSPKELQPLSFSLKPSSEKLNHSADIKEGEKQEINPLLSTGNLKTQVIG
HIETKLNEQTDQPN--SFRVPQSITDPSKIVSSDLLVEKEKPGK----ALHSEQAVKLPD
IS-----TSFADKQDLGVKQFLFLKENLPLEESKSRTANEPEDVKETQVKEALIFPKD-K
SWILEKPERDLASQHEERISGSVQLGSSGS--NDLMTGQLKTVV----------------
-PDKDHTCETKKQVLPHSAEVSPVSLQEPVSTLSTFSGDIETLSTKTYSSEETKL-APKP
KSLVPTGSVERNEAERKQIFSFMGSESLTVEKANAELSRPCKE-GSQEEINLPSERILQ-
KGVSGPSVELIKSETIPSPSKAAPFLAEDAESAL-DS---EKEAH-RSISSLPGEKSLQK
EKTIQSKV-LDVNE-----RGKPAPEV-KTPTPVKL-LSSIQE-NEEPQSAEPSEATQKL
PKQPKAV-ERGLSEEKGKKGIL---SWMSSLFFGSRTPDDRVAE--KDL-ETQPSPSVEK
AVPATLKSEGAA---P-ADFNATKTPTDHLLPETKLKPAEKSRGTLVKSGESQDFK-EKT
TFLSNVEVLQQPQST---LEVSSEDYGKKEILAYSEEMDLNSVVTSADGEERLEIQSYSP
MGEKSMVEEAQNAVPLHVADSKRAQKP------------EISAPSKWNISILKEEPR--S
DQ-----------------------------------------------------KEKLC
FSFDAGDKVPQQPKSASSSFTSKNI------------MKESEKPETIILPVEESERSLID
LGEDRPKKEMQKPTSLKIYEEETKLRSVSPTEEKGNLETRSHSLAEKKVLAEKQETM-AP
LEFRD-NEMGKAQIARGSSPIKLEESKTTAVLQQVSQN-EDHKERYTIMEEEK-------
----DEKQKQSQAFLEGRKWQEIQPYSLNVARSMPEESDI------------------S-
--LSHSSG-E-----TQPLSLVKTLSVTEKSET---------------------------
-----VLLEAHPEIRETRAVGTQPHPKEESKVLVEKTKTFLP--------VDLSYHEEID
KQSVPKEGNLILEK----------------------------------------------
--------------------------------------------SSREVASHSEEKEQ-V
TVSEPSKGVSIDITKESMKQG----------SPSKESERILDHPFDETMSLETPPSLLSS
AKS-----QTLVSRTYPEIDTVKKQEMPWSEL-----------TPD--------------
---------RHTVITIQTSKDLTS-----ERTKQSVVASN----HHLEAVEDAHVNEPSS
SVSSNYA-RFI-----KDASSIDADKMVSSREISKEPEDTYVKDEEF-------TMTSKP
AGL---SEDQKSAFSIISEGCEILNIHASAFISSVDQEESEQMQDKLEYLNEKASFKTI-
SLHDNSEAVSCHKTLK-SKL---EDSDQ-VISLQE-NKQKASF---------NTEGEMPT
YSETDDFTFNQPAA----PS-EEDYFEKYTLIDYNISPDPEKQKAPWKLN-VEVELSKQV
TEDTVSFPESSEESALEHEYDLL-KLDESFYGMEKDDSKL-SHPETRKHLDIQQSAD--R
DVP-KGINRDVDLKSPGMPLFGAEEGVLSRTQIFPTTTKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEGETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSVTQKD
QGQGLEEKAVGKDDSYQPVAA--EGEIW---GRFGTILGEKSLEEEQ-KAMYREGESVGY
VGPLDNEA-MHGKVPITEEVTVVTQK-VSYAIPFEDTHHVLERVDET-------------
-------NSQS------NE------AE---------NASPEVSLNVPVQVSFPEE-EFAS
GVTCVQETLQE-SKVIVPPEPSED--RLRHSPVQDEYEFAESLNYEMVVQ-DTLSEE-LY
SESTPEDVL-SQGKESFEHIS--ENEFVSEVEQSTSAEQKELGRERTEQEQLS-E-LATE
KEQKELKKSQIDTYCYTCRSPISAVDKMFGAHKDHEVATLDTAISAVKVQLAEFLDNLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKKLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLESIVREAEELDE--TVFLT----SFE--------EINER
LLSAMENTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NDLVEEYRLTVKESYCIFEDLEPGHCY
QVWVMA----VNFTGCSLPSERAVFRTAPSTPVIRAEDCTVCWNTATIRWRPAN--LEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGASEQSEAAL
ISTR--GTRFLLLRETAHPALQISSNGTVISFAERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSRSAVQ-AGTLGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
EHPARVGILLDYNNQRLLFINAESGQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSARHK

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-------------------------------------------------GRRNG--GRPC
ATYSFTYLPSHSPLSPACLRSFSGIKGTQLKVNLQPNDNYFFYAKAVNAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISADGMVICFTERRRLTEIPSILGERLPAGGQHYWETT
VADCPAYRIGICSASSEAPGSALGRDNAAWYMHCSEPQR---YQFFSNGVVSN---VHVS
ERPARVGVLLDYGGQRLLFRNAQSGQLLFIIRHRFGEAAHPAFALERPGVLTLHTGIEPP
DLAKHK

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-----------------------------------RVASAAKSTRIQ-------------
-------SSSG------YQGAAYQEASTKQEEQEDITAVPQIEKYVPYVR-APTE--DSL
DDQFTQEHLSCVPTTQETENPDSQ--REE-QHCDVYEDFAESMDYDVITQEELLQDE-IS
SQFTHEELL-FEDRDSFDHAA-DSYEFVNEPEQRTPVELEDSGFVVMYPEKSATNIPQIE
SPQRDLKKAQVDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDQLSKLLAALEE
KSMKIEEFVSDIELRFNSVEENCKKNADLLEKQNEEMLKKVIAQYDEKSENFEEVKKMKM
EYLYEQMVNFQQTVDSAKETLETTVKETDEVDG--FVFLNV-----------NVCFLPIR
LLSAMDTTLSLEKVPSAFSLFEHYADSPGQSNQHSLQHVAVPQTPTVIPQEPNSATSTS-
-IAVYWAVNDRDTIDCFQVYCMEELQANKDA--GALVEEYRVTVKESHCILEDLEPDRCY
SVWVMA----VNGTGCSLPSEKAIFKTAPAVPTIKAEDCTVCWDTATVRWRAAP---ASA
ESFIVEFCRQHSPEG-DGLRSFAGIRKPELKVSLEPNVNYFFYLRAVNPFGTSEQSEAAL
ISTK--GTRFRLLSDTAHPALQISSNATVIHLPEKTKLTGFPSVLGELLPAQGCHYWEII
VSACRSYRIGICYEAITQ-SNVLGLSDTSWCMRCCPTQT----RFLHTGVMSD---VHVT
EHLARIGILLDYSSGRLLFFNAERGLVLFAIRHKFTDAAYPAFALEKAGVLTLCTGMELP
EFVKQS

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----------------------------------------------------------S-
-RLSDQDEEGKTKQTCIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRRRTSK--SKHGSPS--LRRKGNKKRNSLESQ-DVP
ANKKDNPLISESQILNSQKEKSST---GIYDKTRK----KKTASSTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASITLEPDL
GNRDSNIVFKTGKL-----VAQSIEDD----------------REKELSSPWRGALSKG-
----------SKSLT---------SLLRQEDH-KKIDVDSPLKAA--SATM---------
-----------------HTASSYTSNDTAE---QETELGPPQSV----------LQQPGP
EAIPRERKASFLPPD-ASATAF--LGAAKGEFEPDSQETVTPTHDSSVSPPLMDEEKKED
ADSVDHSIS------LKTERDSLERASRSLAASIQEG----FGPERKELDLTSLERAGPV
SEQLTPPHLDLTSL------------ERAEQVS---------------------------
-------------------EKLTPPHLDLTSLERA-GPVSEQLIPPHLDLTS--L-----
-------E----R--A-G-L--V-S--E-Q--L-T-P--P-H--L-D-L--T-S--LE--
-R-A-G--------LVSEQ---------LTPP-HLDLTSLERAEPVSE------------
--QLSPP-----------HLNV-------------KGEKEENVPEPSISLSEPLVSEKLE
KAEIETSLPVAATHEPEDANVVE-EEIIELDYPESPSVSEKPLSPCL-APEVEQ------
------------------------------------------------------------
---------------NKEETILPLLT-P-------------TPERVALSEEEGE----EN
ESVSTDSAFVSEYSVL----------QDLNHELEK----QET------------------
----------------EPVSPSNVKAASEPAVLS---------------EEENEEFEPYS
PASASASEH--------------------------------------SLSLSTTEKTSEC
QSPLFSAGASEHMVLSSEEASES-----GHYTPDSTSPS--------------EYSIPSQ
AAKESL--RTSIDHTSPLKS--EAVSDHVILSEEEKKGTGLYSP----------------
-------------------DHAVLSEGED-LGSEHLTPDATLTSQHAVPPNVTHESPKKV
IDDVFPLKSKGVSEHMIFSEGE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDTG
LYSPDV-ASVSELT-LLP--------FTTETTSECQSPPP-----SAATSEHAVLPEEDL
G-----KEERGDIG-------------------------LYSPDEMVHRAPLNLK-----
------------------------------------------------------------
----GASSPMNFSEEE--QEDIGPFSPDSAFASEFSFPPYATQETEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSVPPYR-PETKKNEIEPDSLLTAISASGYSGF
SEADEEEI-ASTAA---TPV-PEHLS--SSEKQQSETSPSVSV--PEDLSLPPSTN--KA
EEAEIKPDVQTTSASVSKYIISAQK-------QIRQASL-EAESEDLIPSYLT-------
--------N---ELEKGEIKTS-LSVAATPS--SFPAQPSMAKDETKPVLPATQYSVAPD
SV-------------------HVIKKEQEPKASLTAQ---------AANEQM--------
-ALLKVK--------------SKEEIVPDSQEAAVRVS------QD---QEMEPQPPN--
--VPGSGMKYSVVPDL-VD-----------------------------------------
-------------------EPKKDVKPNLAPTVTS--ELEQRMLSENEP---EVIKPYSP
LKETSLSAP----------------------------EILS----------AVKTEVKHD
SEIIGTP----KGLHSASPGVEKHIE---------------------------------H
GPPA--------PEFSALS--TEIKKEVEPSSSITTTS-LTK---------HDS------
------------------------------------------------------------
---------------------------------------SLTKLAKEEILTGL-------
-----------------------------------SLSTPIEH-LILTEVGK-------N
ELESGLP----------------PN--SV-------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------SASEVSEPEHGLLLNLGGEIKKKETELLSSQNMSPIPKHI
VPRGKNEEMASSSPESENLLSDDLAPMLPPLSDDRNKQAMEMSPAAQGGFLSEKQD----
Q-----LSLEPEKKDKPHQVSELPT---AEAEFTSGVGRQSGSIDTKQIKSPITETGDSV
LEKGLAELRSREEGKEENREL---------------------------------------
------------------------------------------------------------
---------------------HAITEPSKIASTDLLVEEEKPEK----ALHSDQTVKLPD
VS-----RSFADKQDLGIKQFLFMEQNLTLEESKSFMTTEPADVEETQMKEALISSKD-E
NWMLEKPESALASHDDERAVGSVQLGSSGS--SDLMTGQPKAAL----------------
-LDKDQACE---------------------------------------------------
------------------------------------------------------------
----------------------------------------EKAAH-RSISPLPGEKPLEE
SKMGQSKVVDDDSK-----RGKPASEV-KTPTQIKP-LSSIQE-NEEHQPPESPEVSPKP
PKQPKDT-EPALAEEKGKKRISSFTSWMSRWFFGSSTSDNQVTEK-EDL-ETQPSPSVEE
SGAVT-EPKGVA---S-ADLNATEKPADRLLPEAKLETAEKSRDALVKSGEGQDFK-EKP
TFLSNVEVLQQPKST---FEVSNEDYGKKEILDYSEEGDLNSGVTSAGSKEHLGIQSYSP
MGEKSIMEEAKSAVPLHVTDSKRAQKP------------EISPPSKWNISIFKEEPR--S
DR-----------------------------------------------------KEKLL
SSFDAADKVPQQPKPASSSFASENI------------TKESEKPESIILPVEESKGSLID
LDENRLKKEMQKPTTLKISEEEIKFRSVSPTEEKENLETRSYSLAEKKVLAEKQETVGTP
LELRDNNEIGKPQITQESSPIKLEEWKAAAVLQEVHQN-EDHKKRHQII---E----EEK
GE---EDEKQSHVFSEGKKQQEIQPYSVK--------SDI------------------S-
--LSHSLG-E-----TQPFSLIKTTSITEKSET---------------------------
-----RISEAHPEIRETKAAESPPHPLEESEVLVEKSKTFLP--------VDLPYRGERD
GHSLPKEGNLVLEK----------------------------------------------
--------------------------------------------SSRDRVSHSEEKGQ-V
TVSELSKAGSIDITKESMKQG----------SPSKESERILDRPFDETKSLETPPYLSSS
GRP-----QTLVSGASPEISTVKKQEMPWSEL-----------TPD--------------
---------RPTVHTIQTSKDQTS-----EISKQSVLISK----HCLEAVEDAHVKEPRS
SASSNYA-QFI-----TSASAISADKVVSAREISKKPEDTYVKDEEF-------TVTSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFISSVDQEESEQMQDKLEYLEEKASFKTIS
-LPDDSEVVASPKTLQ-SKL---EDSDEKVTSLKE-SKQKETH---------NTKEEIST
DSETDDLGFNQPTT----PS-EEDYFEKYTLIDYNISPDPEKQKAPWKLT-VEAELSKEV
TEETVSFPESSEESALEHEYDLV-KLDESFYGMEKDYSKL-SHPETQKSLDIQKSAD--R
DAP-KSINRDADLKSPGMPLFDAEEEVLSRTQLFPTTAKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEGETASEGDSVNSEASFPSRSSDTDDGTGIYFEKYILKDDILHDTSVTQKD
QGQGLEEKPVGEDDSYQPIAA--EGEIW---GRFGTILEETSLEKEQ-KAAYREGESEGP
VETLDKVA-VQKKAPVTEEVRVVTQK-ISYAVPFEDTHHVLERVEEM-------------
-------SGQS------NE------AA---------DASPEVNLNVPVQVSFPEE-EFIS
GATYVQETLQEEPKIMVPPEPSED--RLRNSPVQDEYDFAASLNYEVVTQ-DTLSEE-LY
SESTPEDVF-SQGKESFEHIS--ENEFVGEVEQSMSAEEEELGREKTEQDQLSSE-LETE
KEQKELKKPQIDTYCYTCKSPISAVDKILGIHDDHEVSSLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKKEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLETIVREAEELDE--TVFLA----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVVDSFQVYCMEEPQDDQEV--NELVEEYRVTVKESYCVFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVICAEDCTVCWNTATIRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPSDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSDGTVISFAERRRLTEIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETTWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYTNQRLLFINAESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSARHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MVTVQREDSGITWETNSSR-STPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNKKRNSFECQ-DVP
TNKKGSPLTSASQILTTEKEKSYT---GVYDKARK----KKTPSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKG-
----------SESLT---------SMFSHEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPG-TPATVF--LRTAKEECELASPGTAASENDSSVSPSFTNEVKKED
VCSAHHSIS------LEA-------ALPDLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIDTSLPVAATPKPEDSNLVE-EEIIELDYPESPLVSEKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------KEEALILPLLATS-------------TPENAALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----RES------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSPLFSTVTPEHMVLSGDEASES-----GRYTPDSTSAS--------------EYSVPSQ
ATKESL--KKVIDHKSLLIS--KGVSEHMIPSEE-KEDTGSFTP---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSECFTPDSKLISKYAAPLNATQEPQKKI
IDEASQFKLKGISEHTVLSVEG-KEDI-GPASPDS-------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VIASEYTVLSVE-GKEDIG
PSSPDS-VIASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEDT
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFASEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTTA---TPV-SEQFS--SSQKQKSETFPLISP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPPHLT-------
--------S---EVKKGEREAS-SSVTAIPA--SLPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--IPGFEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSEKEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPHA--------LAFSALS--EEIKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVGH-PVLTKVGK-------G
ELGSGLP----------------PL--VTSTDEHSVL-AEEDKVA---------------
---IK-GASPNETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------YSDESEEARVE------DKQGL
SCSTVRDSEHLVSSEKKSLVSTSEVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENS-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDIALA
E-----LSLEPEKKNKPHQLLELPN---AGSEFASGLGRQSGSIGTKQAKSPVTETGDSV
LEKGPAELRSRE-GKEENRELYA--SATM-PTTSELSSLLREESQNEEIKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLVE--QKTEK----ALHSDQTIKLPD
VS-----TSFADKQDPDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEELKL-AEEP
KSFVLAGNVERNIAEEKESHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVRTTHFLAEGVEPAL-GN---EKEAH-RSTPPFSGEKPLEE
SKMVQLKVIDDADE-----EKKPAPEV-KIPTQRKP-ISSLHS--KEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKGKKGISSFKSWMSSLFFGSSTPDRKVAEQ-EDL-ETLPSPSVEK
AVTVI-EPEGTI---P-TNFNVAEKQADHSLSEVKLKTADESRGTLVKSGEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEVNINSVVTSADGEKHLEIQPYSL
IGEKLIMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKDSEKSESIILPVEESKGSLVD
LSEDRLKKEMQNPTSLKISEEETKLRSVSPTETKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNEIGKTQITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
DE---EKENQVYVLSEEKKKQEHQPYSVNVAESMIKESNI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSDA---------------------------
-----VLSDAHPEIREAKAVATQPHPLEQSKVLVEKTKTFLP--------VALPCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMPDHSEEKEQ-F
RESELLKGGSVDITKESMKQG----------FPTKESERTLAYPFDETKNSETPPYLLSS
VKP-----QTLVSGASPEINAMKKQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTF-----NVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKDEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTV-
PLHDDSETVACHKTLK-SRL---EDSDEKVTSLKE-SKQKETR---------HTEEKTST
DSE-TDLSFIQSTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEDKLSKEV
TEEAISFPVSSVESALEHEYDLV-KLDESFYGPEKDHDIL-SHLETQKSLGIQKSAD--R
NVS-KDVKRDVDSKSLGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKNKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVGH
VETLGNIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPDVNLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILVPPEPSEE--RLRNSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAEQKELGSEWKEENQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASGDSS-----
--HTTDSVLGW-------DEDEEAARELETEEDTE----GEEEET----AAESEEEPDA-
-RLSDQNEEGKTKQECIISDPSFSMVTVQQEDSGITWETNSSRSSTPWASEESQTSGVFS
PERSAL-NSLPGNVSFIVDEVKKTRKRTHK--SKHGSPS--LRRKGSRKRNSLELQ-DVL
AHKEDSPLISESQVLDTKKEMPSA---GIDDKTRK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
GNCDSEIVSKRSKL-----EAQSPEDD----------------TIRELAPPWRGALTKG-
----------SKSIT---------SLFSHEDQ-KKMYTDSPLNAT--HASE---------
-----------------HTVSSYSRNDTTD---QEVHLRYPQTV-----------QQPTD
KSKPQETEPLS-----TPAT--VLLETAKEEFEPDSQGMET----SSVFPDSVADVKQEK
RFST--------------EKETLETGSPGLLPSIQEK----FEPDKEELELSLIEKTDLD
SEHLISPEPSVQ------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------GEEERVPEAPISL----------
-KEVKSSPPITDNTEPEDSSLV--DEIIELDYPESPVISQK-------------------
------------------------------------------------------------
-----------------EELILPSQMTP-------------TPEHATLSEEERE----EK
ESVSTDSAFVSEYSVP----------QDLNYELEK----QNE------------------
-----------------AVS----------------------------------------
---------------------------------------------------PSNVETSES
QSPLFSTVPSDHLVLSGDEASES-----GCYTPDSTSAS--------------EYSISSH
DTQEFL--KKTTDHDPPLKA--QVVSEPMILTEEEKEGTEPHSP---VVDASSEYPLSST
ITEETSEHHSPPLPP-ATVGHAVLSEDED-LGSERFVSSSKLTSKSSVPQNETQESPKKI
IDNVPQFKPESISESMFLSEEE--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
LYSSDM-VCAPEYS-LPP--------NTTEVPSECQALPP----NLAPSLDHVVLSKEET
I-----ETQRYSSPSL---------SE--------------SLEEIVHPAPLHLK-----
------------------------------------------------------------
----GASPPTNLSEQE--QEDAGPFSPDSAFVSEFSFSPYPTQELEKRELECDSPLCLTS
PSEHTVLSDEDTEEMELFSPDSAS--QVSIPPYRIPEIEKSEIEPDSLLTSRSASGYSDF
SEVNEEEEVGSSAT---TPV-PEHFD--LSQPHEAEPFPRMPV--SEDLSLPPSAE--KE
DQAEIMPDAPTISISVSEYLIRAQQ-------QKAQASV-EPRPEDLVPLHFS---S---
------------VSKKEEIKGSSAAAT-TP----PSLPASVAKEETKPALLTSQPSVSPE
SV-------------------HEIKKGQEPKALLTME---------TTDKQM--------
-TFLKVR---------------EEETAPGSQEATARVS------QD---QKLKPQLPN--
--VPGSGLKY--------------------------------------------------
-------------------EPKTDVKFNLAPTVTS--EPEQRVLSEKER---EVTKPCSP
PKETSIFEP----------------------------EVLS----------GVKTEAKHD
SKIT-------RALPAASLGLEKEAA---------------------------------H
HPPVP-------PAFSASS--EEMKKVTEASSSAATGP-GAK---------LDS------
------------------------------------------------------------
---------------------------------------NVTKLGREEILTDS-------
-----------------------------------SLASPVEH-PSLAQVAN-------S
EMGGDLL----------------PP--IMSIDEDSGLTEEEKVSI---------------
---K--------------------------------------------NAASLTEHSVWS
KVETEEVKPGLPIPQMPSSQ------------------HLDVSEEARRG------DKQGL
SLSTVLESQHLVSSQKENSVSVSEVSKSE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------KLGSRQPDSPGR--HDLMPGQLKAAS----------------
-LGMDHTSEIRKQVLPHSAEEPHLSLEEPVSTLDVSSGQAENLSTTTYFSEEVEL-AQEP
KSVVPTGKVERGVAEERQICSFTDSKNLISEKTNTELSRPCRA-DTQEEVKLLPERTFQ-
KSVFA-------------------------EPIL-DK---DKEAH-RSIAPLSGEKPLQE
PELVQSEATDVVKE-----GRKAASEV-KLSTQSKP-VPSVPA-NVAPPHPETPEVTQKP
SKKPTVT-EQGLPEEKGIKGISSFKSWMSSLFFGSSTPDNKVAEK-EDL-ETQSSPSVEK
VAPAK-EPKGTL---P-VDVNATMKPAVHSLPEVKLKPAEESRDISVKSSEGQGVK-DKL
IFLSNVEILNHSESN-----------SEKEIPDHSEETGTNLV--TSAGDEHLGIQLSSP
RSEKLVMEDTKNVIPLHVTESQRRQKP------------EISPPSMWNISVLKEEPS--S
AQ-----------------------------------------------------KEKSL
FSLDMVDKMPQQPKSASFDF-------------------EPEKPEPVILSL-ESKGSLID
LGEDRLKKEMPKPTSLTHSEEELKR----PMEKKDSWETRSSALAEKTELEGKPEIT-AP
LELRENKEIGKLQATPESQPCKLEESKAAVKLEHIDAS-EEHIERSSMTAAAE-------
--KRGGKEEQAPLFSEGKKEET---------MPEPGESAV------------------S-
--LDRSLG-E-----TQPPSLVKTPSIIEKPER---------------------------
-----MFAEVYPEIRERKLPETQPYLLRGSKALVEKTKASHP--------MELPCDEEMD
EDSLAQGGNLGLEK--S-------------------------------------------
---------------------------------------------SRGMVGPEEGRGQ-F
TVSELSTGGSMAVIDENRKRR----------SLVNDFERTSEQTPDETEPLETPPTQLPS
AKP-----QTPLSGTSLETDAVKKQEM-W---------------SE--------------
---------RPTVHTIQSYEEHSA-----EMPKQSVLVSK----RHVEAVEDTHRNEPLA
SATSSYA-QFI-----LNASAVNTDGMTPIKDTPKEPEGTSVKGEEF-------SVTSKP
AGL---SEDQKSAFSIISEGCEILNIHAPAFIPSVDQEESEQMQDKLEYLEEKTSFQIK-
SLRDENEVVASHKTQE-SKL---EESDRKVTSLKE-NEPKEIH---------KIK-EIFT
DSEKGDFTFMQPTI----SS-EEDYFEKYTLIDYNISPDPEKQKEPQKLT-TE-EFPKEA
TEETISFPESSQEGALEHEYDLV-KLDESFYGLEKDHRKL-SHSEMPESLVIQNSTD--G
NTS-KGVSRDVDSRSPGMPLFDAEEGVLSRSQIFPTTAKAVNPELLEEPHALAFLYKDLY
EEAVGEKKEEEETSSEGDNVNSEASFPRRQSDTDDGTGMYFEKYILKDDILHDTSITQED
QGQGLGEKPVGKDDSHQLRAA--EREIG---GKAGTTFWEKSLEEQH-KAGYREGESGGG
HTETFDEVVMQGKSPITEEVRAVTQK-MSYAVPFEDTHRVLESVDEP-------------
-------SSQG------NE------AG---------NASPEVNLNVPVQVSFPEE-EFAS
GATYIQETSQEEPKVPAPHQSSEE--RLRNSPVQDEFEFVDSLNHEVVGH-DILSEE-LY
SESTPEDVL-SQGTESFEHSR--EHELVSEMEERIKAKQKELDREKTEQDQSASG-LVTK
KIQKEPKKSQIDSYCYTCKSPVSEMDKALDIHKDHEVSALDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEELKKKKM
EFLHDQMVHFLQSMDMAKDTLETIVREAEELDE--TVFLT----SFE--------EINDR
LLSAMESTASLENMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPSSATSTT-
-IAVYWSMNKEDVVDSFQVYCMEEPQDDQEV--NELIEEYRLTVKESCCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATVRWRPAN--PEAT
ETYTLEYCRQNSPEG-EGLRSFSGIKGLQLKVNLQPHDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTSSLCRARNAQA------FAFLPSATQRRHPEQIPSVLGEELPACGQHYWETT
VTDCPAYRLGICSSSAMR-AGTLGQGETSWYMHCSEPQR---YTFFYSGIVSE---VHAT
ERPARVGILLDYTNQRLLFINAESGQLLFIVRHRFIEGVHPAFALEKSGKCTLHLGIEPP
DSIRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASSDSG-----
--LAAQGLLGW-------GAEEEEP---ETEEESE----GEGEET----AAESEEEPDA-
-RLSDEDEEGKIKQECIISDPSFSMVAVQREDSGITWETNSSRSSTPWASEESQTSGICS
LEGSAL-TSPPGSVSFIMDEVKRTRKRTQK--SKRGSPS--LRRKGSKKRNSLESQ-DVL
TNQEDGPLISEKPVLNTEKEKSSI---GTYDKTRR----KKTESNTPPITGAIYKEHKPL
VLKPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRRGKE--SSISLEPDL
SNGGSNIASQR--K-----LAQSPEED----------------RARELAPPWRGALSKG-
----------S--MT---------SLFSHEEQ-KKTYTDSLLNAT--SSTE---------
-----------------HTLPSYSRNDTAD---QEEHLRPSQTV----------QQQPAD
ESKTYRTEPPS-----TPA--TMVPERAKEELEQNSQGMESSE-DASGLSGLANDVEQEG
MVSVNHSMS------WEAEKESLKTGPSRPGPAIQEG----FEPDMEELEPISREKMEPV
SEPVTSSEPIDHREEEHAP---EPIDHREEEHAPE--PLVHREEEHAPEPLVHREEEHAP
EPIVHREEEHAPEPIVHREEEHAPEPIVHREEEHAPEPIDHR-----EEHAP--EPLVHR
EEEHAPEPLVHREEE-HAPEPI---------VHREQEHA-------------------PE
PIVHR---------------------EKHAPEPIVHREEEHAPEPIVRREEEHAPEPIVH
REEEHAPEPLVHREKHAPEPIVHREEEHAPEP--IVHREEEHAPEPLLSLASQ-----EV
ESGAETSLPITDTIEPEDSSLE--EEIIELDYPESPLVSEKDSPLPL-SPEVEH------
------------------------------------------------------------
---------------RKE-PILPSQMTF-------------TPEHITLSEEERE----ES
ESVSTDSAFVSEYSVL----------QDLNRKSEK----LEV------------------
----------------EAVSVSDVKS-SEPAVFS---------------ED-EEERESYS
PAVTSVSEH--------------------------------------SLSPSTTEKTSST
QSPLFSTVSPDNLVLSGDEASET-----E--ASDSLSAT--------------EYSGPAH
V-QELL--VRAGDPKLPLKS--QHVSEPIIQTEDEKEDIGLLSS---AVDATSEYPHSPS
LSEKASECHLPPLA--TTLRHAALSEDEG-LESGSFVSDSKLPFKPSVPQSATQEPPEKT
GDDTPQFKPKGLAEPTILLEEE-KEAI---------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------E
LSSSSE-VPAAERT-LPP--------QTTELLSESQAPPS-----WPTSSEQEGLSEERS
G-----EGQQRSFS---------------------------STPELVHTSPLLLK-----
------------------------------------------------------------
----GASSPSALSEPGQEEDSIGPLSPDSAFASEFSFSPYPTQELERRELGRDSPLCLTS
PSEHTVLSDEDTEEAELFSPDSAS--QVSIPPYRIAETERNKVEADELLPMSPVPDFPYF
SGADEEET-GSSVA---TPV-PEHSA--PSKERKEEPFPSIPV--FEDLSLPPSAVMTTT
GQAETKPDVPTVSTSVSEYLILAQR-------QKTQASL-EPEAEDVVPPPLT-------
--------S---GWEETDAKSSS---TASTIAASASAVSSVVKEETASILSTSQFSVSPE
SA-------------------RVPKTEREPKASLTLT---------SAEEQM--------
-ALPKVR---------------REEIVPDSQEATAHKS------QD---QTPEPQPPN--
--VPGSGMRYSVLSDM-GD-----------------------------------------
-------------------EPKADVKPDLAPAVTS--ELEQRMLSKNEP---EVVKPHSP
PEETSISGR----------------------------KVLS----------AVQKEVKQE
SKIT-------RELPAASSGIEREVE---------------------------------H
HPPAP-------TALPALR--EETERETKASVSATPVP-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NSAALGRDEILTDS-------
-----------------------------------SLAGPAEH-PGFKGVGE-------R
GLGSGEP----------------SL--TMSAADPTVLRAGEKEPI---------------
---KE-AAAVLDSSSFRGSAW--PEAE-----E-------KGRLESSLSLSSPSELSDWS
KVETEEVKRGWPGAKVP----------------------SDVAAETGVE------DKRGI
SLSPAPESKESTSPQKKNLVSVSEVLRPEPKLPIDLWSEVEREDTEPPP-SQVSPTPKHT
VPDDKPEEMT-RSPDSENLVSDDLAPTLLALRDEMNGQAEETSSPVLGSFLSGKEELV--
K-----LPPE---PKKPKRFSEAPT---VGLELTDSRDR-DGSLGIEIVK-------PSV
LEKGPTELRSAGKEQEEHRGLPV--PATS-------------------------------
------------------------------------------------------------
--------------------------PLETASSDLPIKQKELKK----TLPEGQAVKVPD
VG-----SSFAEKPDLGIKQLAQRKEN--LEQPKPFMTAEPADVIGTEVKETLISPKD-N
TRMLDKPDGL-VSQHEDRKPGPRQLESSES--KDLMPEKLGAAP----------------
-LDSDHTPGIRKQEE------PHLPLQEQASILRVSSGKVETFTTKTYLSEETEA-----
--VVPVGKTDRGRAEERQNSSFMESENSVSEKTNAEFPKPCKE-DVQMELKLPLGRTIQ-
KSGTGPSVEQA----TPIPASSAHFLAEVVEPTV-GK---NQE---ASIAPVSGEKPSQE
PTRVQSKAVGDAEE-----GRKLAPDV---------QVPAVKA-NVAPQPPETPGVTQKP
SEKSLVA-EQCLPAEKGKKGISSFKSWMSSLLFGSSTPDNKVADN-KDL-ETQPSPSLEK
ALTAV-EPKGAV---P-AEVTVAEKPGVHSLPEVTVKLGEEPRGG------------EKL
TFLPNTDVLKQPASN-------SENYGKKGLPGFSEGMGENL--ATSAGDEHPGIHPRSP
MGEKVGMEEAQNTAPLHVTESQRHQKP------------EIAPPSMWSISVLKEEPS--S
GH-----------------------------------------------------KEAQL
LSSDVVDRTPQRPESTLSAFARM----------------DSEKQAPVSLPV-ESEDSLID
LGEDRLRQEMPKPTSLERHEEEVER----PAVEKDGWGTRSFSLAGEKGLAEKQEIM-AP
LEVGENKAVGKLQMMPESRPFKSEGSKAAERLEQRISPREELMEKPSKTLASE-------
---RREKEAQERVFPEGEKEGGLSSS-PAAAMPVPGASAI--------------------
-----SWD------KAQPPSPVKPPPVIEKPEH---------------------------
-----IFTEVYPEIGERKAAETKPHPQEEGKTLVEKTKASR---------VEPPHGEEVD
GHSFTQGGNLELEK--S-------------------------------------------
---------------------------------------------RESRVDLKEERRQ-F
VMPELSLAASVAAEDGHAQPR----------PLSRAAERTAGHITDETNNLGPPTLETSL
EQT------------------AK----------------KQETRSD--------------
---------RPTVHTIQTSKDHPE-----EMPKQSVLISK----RHLEAMEDVHRNEPLS
SAASSYT-QFM-----LSASAVSADGAPPVGGTPQEPEGTSGKGEEF-------SVTSKP
AGL---SEEQKSAFSIISEGCEILNIHAPAFIPSVDQEESEQMQDNLQYLEEKSSFKSI-
SVCDERKAVASHKTQK-SEL---EVPDRKITSPTE-NEPKESY---------QTKEETAT
GSRSGDFTSIQPGV----SG-EEDYFEKYTLIDYNLSPGSERQKSTVE------GSSEEA
TETLTSFPESSAEQTLDHEYDLV-KLDESFYGPEKNGSKS-SHAEMPKSLVIQKPSE--E
NAP-KGVGVDVDSRSPGMPLFDVEEGVLSRRQIFPTTPKAVNPELLEEPPALSFFYKDLY
EGALGEK-NEGETASEGGSVDSETSFPRRHSDTDDGTGMYFEKYVLKDDILHDESVNQED
QGQSLEEKPVGENGSQQLRIA--ESEIG---RKPGTSFWERNLEEQH-KVIDREGEPVSH
TETLNEVA-TQQKAPVTEQVTAITQE-MSYAVPFQDTHRVR--TSEP-------------
-------SSQG------HE------AG---------NASPEVNLNVPVQVSFPEE-ESTA
GATYAPEVSQE---ELVPCVSREE--RLHNIPVQDEYDFVDSLNQEIVSQ-GILPGE-PY
SEAPPKEVL-PQGTESLSHAG--ERELMSEGEPRKSASQEEWDRGG--EDQSARE-SVTT
KTQKEQKKAQVDSYCYTCKSLVSEMDKVLDIHKHHEVSALDTAISAVKVQLGEFLENLQE
KSLRIEAFVSEIESFFNTIEEKCSKNEKRLEMQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHDQMVHFLQSMDTAKDTLETIVREAEELDE--TVFLA----SFE--------EINER
LLSAMESTASLENMPAAFSLFEHYDDSSARGDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSVNKEDVVDSFQVYCVEEPQDDQEI--NELVEEYRLTVKESCCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPFTPVIHVEDCTVCWNTATVRWRPAN--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLSPNDNYFFYVRATNASGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSNGTVISFSERRRLTEIPSVLGEELPACGQHYWETT
VTDSPAYRLGICSSSAVR-AGALGQGESSWYMHCSEPQR---YTFFYSGIVSE---VHAT
ERPARVGILLDYTNQRLLFVNAESGQLLFTVRHRFNEGVHPAFALEKPGKCTLHLGLEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------S-
-RLTDQNEEDKTKQECIISDPSFSMVTVQREDSGITWETSSSRSSTPWASETSLTSDMYS
MEGSTV-SSPPGNISFILDEGKKVRKRTRKSSSKHGSPA--LRRKGGKKRHSLEGQTDVP
TNAKDKTSISDGK---SEQEKSSF---GTYDKTRK----KKTVSNTPPITGAIYKEYKPL
VLRPVYIGTVQYKIKMFNSVKEEIIPLQFYGTLPKGYVIKEINYRKGKD--ASITLEPDA
-NQDSSVFSKASKS-----VTQNIESN----------------KEKQLSPPWREAISKE-
----------SRPMP---------SFLKDTEKSKEINSFSPPNTVAASGLK---------
-----------------HTVSSYSSNEIME---PQSLTSLDSAI-------------PVE
ETPMNEIQI--DSSD-AATSELMSPKMVKEDLKAETQETVVLLPTFSTSPSFVDEVGEEN
LIST------------KAEQETFESDAPVTAACAPDS----LDTKVENLGLSSL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------EKEEPV--------------
------------------SPTG-------------EWEMEETKP-------EPPALREMK
EEEGDISLPITSGPELESSYVSE-EEIIEIDYPESLSPSENAILSPL-VHEGER------
------------------------------------------------------------
---------------EEAEPDLPLLATS-------------TSENVALLEKERE----DI
GPISPDSDFASEFSSL----------SYSTHELEE----KEM------------------
----------------KPVSPPAALSPSEYEILS---------------EEE---TVPCS
PEFTSVSEY--------------------------------------SATSPTAE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EDSIGYQSPIH-----LASTSEATIFSEEET
L-----ESERYTPDST---------SAS-EYSIPPYAAQELQKEETGQRTPLSSI-----
------------------------------------------------------------
----ATAEHMIISEEE--KDDIGPYSPDSAFVSEYSVSPHPVRESEKEESERDYPIHATS
PSEHAIFNEEENEEIEPFSPDSAS--DFSVP-YTTPEQEKRADEPSSLETSMSVSEYSIF
SEAEKEME-SHSPRAPDYVMEPSVAPGKAGEKVASDSMSIEKPVPQQEISLKNKEN----
----LKDSQQ--AKSLAGFEISQAETKEKVRQDKEQAA--IPKSQHLVSSKSE---KEET
PHLPELKLSSLSEENKKEIGLDSPQATASELKPSLL--PKTVKEEIQSDSPLPTTSVSDA
VL-------------------SKASKEELKVSSLSEE-------------------NKKE
IGLDSPQTTASELKPSLLPKTVKEEIQLDSPLPTTSVSDAVLSKAKENKKGIGLDSPQ--
--VTASELKPSLLPKTVKEEIQSDSPLPTTSVSDAVLSKASKEELKVSSLSEENKKEIGL
DSPQATASELKPSLLSKTEENKKEIGLDSPQATAS--ELKPSLLPKSVK---EEIQSDSP
LPTTSVSDAVLSKASKEELKVSSLSEENKKEIGLDSPEATASELKPSLLSKTVKEEIQSD
SPLPTTS----------------------------------VSDAVLSKAKENKKEIGLD
SPQAT-AS---ELKPSLLP--KTVKEEIQSESPLPTTS-VSD--------AILSKASKEE
MKVLS--------LSEENKKGIGLDSPQATASELKPSLLPKMVKEEIQLESPLLTTSVSD
AVLSKASKEELKVSSLSEENKKGIGLDSPQATASELKPSLLSKTVKEEIQSDSPLPTTSV
SDAVLSKASKEELKVSSLSEENKKEIGLDSPQ---ATASELKP-SLLPKSVK-------E
EIQSDSPLPTTSVSDAVLSEEKVDL--SSLPTDHLVLNEN----L---------------
---FE-IGSPIEIAAAKVPVW--SEVD-----NEVNL-------H------------APS
KVLKEEEKPESPIP--------------------------EHSFLSKVG------NDQGV
PPLTVPAVERSTLSEKQASESSTPASMTESTVPPYMAVEMEKKYAKVPLSKTVISVSDQR
VTSQEKEEIKSPLNELETLGIEDLSMKSITPTGERSRQEPGMLMSDKT-------T----
--------------------------------------------------------GSSV
LERA--------------------------------------------------------
------------------------------------------------------------
--------------KKETKRSQNIPEPSKMASFDLSEEQARQKS----MLCPDDIVNLSD
SSIS---SPLVDQKDIAMKLPSFAEANLPLEESKSIVTVEPRDVKDAK--ESLSLQKE-G
IWLQKEQSQEQTRPDKERVLESGQLYSSAT--DGRPLGQLMSVS----------------
-PEKKQTFEHIKQENIYPAEEPDLSAQIPTSPLGRPEDHREKLTTQTYFSPEIQM-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------AEKPRS-TVVVEK-AGRPEALDSPELINKV
PKQAETAPPSTATDGKAKKGVSSFTSWMASLFFGASAPEKDVNEK-EA----LPSPAADT
SVLEG-EVKMTVPAIP-DDFNEAEKPALSPLSVSGLLPEKEPQTILIKASEEREQK-ETP
LSLPNQVDKESSKLTALRVEKMSLQTH------------------------HLSES--SL
PGAESRTALTESGKPRQLKE-------------------DF-----MFLSA--------M
EE-----------------------------------------------------DESQQ
LSFAKADLFR-EPQS---------------------------------------------
-------------------------ASVGPTER--NKEERSDAITVSPEEEGEQKGSITD
LSLGENNQ----------------------------------------------------
---------------------RTQLPSAGRTNFASEESGI------------------T-
--CGISHD-ETENLKNQTYSLAKA--KSGESQM---------------------------
-----MLSVAHPEIKETKTVGIQPTSLREKDSLEEKTKTLIP--------TSPSHRVEVD
QENIC--ALPDMES--LRSKVPSHSEEKEQH-----------------------------
---------------------------------------LLFSDTPHAMVE---------
----PSKEILSDITKESKKQE----SQPEFGRLVSRESKTLDSPFDESRSLAQLPSSPEA
IFSPM-KSPNVISVSSPEVNK------------------SEISSPE--------------
---------LTGAGQTYQAKDGAP-----HSPVPSTFVSKQVSDFQTKAMEDFQVDKPYP
SAVHDSN-EVT-----CDMTSTSRKEISSSESLMKESENLFVKDGAF----AVPMVTSKP
PGL---TEDQKNAFSIISEGCEILNIHAPAFISSVDEEECEKMRDKLEYLEEKTSQSIQ-
PLHDGSEVTEGHEVLR-NES-LAGDSDVDI-SLGKGKIQEKTH---------PAEEDVST
DS---DVPFNYDTM----PS-EVDYFEKYTLIDYNISKEPLKKESFQKQD-VEGEPQKKI
PEETTSFPESSADKTLECEFDLM-KLDESFYGMEKEDGKV-SYKESQSSLPTLKSTD--S
ETP-RDVNRDVNSKSPGMLLFSAEEGVLSRKQLFSMEVKAINPELLEEQPALAFLYKDLY
EEAAGDKKKEDETISDKESLKSDGSFPSRHSDAEEETGMYFEKYILKDEILHDASGYQKD
QSRPLEEIPVDKNDSCQIKAG--KGEVW---GRFGTILGEKSIEEEQ-RAMFGEEELRSS
VENHKDKE-LQGKVPITEEVQLASQK-ISYAVPFQDTHYILERVDEP-------------
-------VDQA------NE------EE---------NASPEVSQHFPVEVSYPEE-ESMS
GATAAPERLQVEPQGFVLPEMMES--RACSSPVQDEYEFAELMSYGEAARENLLSDD-MF
SESTPEDVL-SQGRESFELVGENAEFMKEEEEQSRSVPQKDLGSEVVEPERPLAE-A--E
DAQKEAKKSQIDTYCYTCKCPISAIDKIFGEHKDHEVAALDTAIDVVKIQLGEFLDNLKE
KSLKIEAFVTEIESFFNTIEVSLVKNLIYSTFRNEMSLKSSLCEISETIVSKESINKSMI
SFSPQFYLTFLVQQDNCINMVEKASRKGPPIDFFYSPALH----SLQ--------KLPQK
LTKNVKIVLNVPELINSFSLFLIKQDSMILSCE-GWYQLLIPTNSAILNSDGKMSKETSL
LVGFRVKKNEKDFIDPFSLYLKIEYSHDHES--KELLTSIPTSTVQSILLYGKIKNEEPT
KRHLLQQQAGLGSRVC-VHWEWSNFACVAADDGLNLSSLLIFWGSFIVHWGFRALTLEIT
ILQGLEACKVHYSPLHLSFISYSGIKGFQLKVNLQPNDNYFFYAKAVNAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALQISSDGTVIRFTERRRLTETPSVLGEQLPPCGQHYWETT
VTDCPAYRLGICSSSNMQ-GSALGQGDASWYMHCSEPQR---YKFFSNGTVSN---VHVT
EHAVRVGILLDYSNQRLLFINAESGQLLFTIRHRFTGPIHPAFALEKPGQFTLHLGKEPP
DFLRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASCDSN-----
--HAGESFLGS-------DRDEEATRELETEEESE----GEEVET----AAESEEEPDS-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTPK--SKHGSPS--LRRKGNKKRKSFESQ-GIP
TNKKGSPLTSASQVLTTEKEKSYT---GIYDKARK----KKTTSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNLVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSGSNTVSKTSKL-----VAQSIED-----------------KVKEVVPPWRGALSKG-
----------SESLT---------LMFTHEDQ-KKIYADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRYSQSV----------PQQPED
EAKPHEVEPPSVTPD-TPATMF--LRTTKEECELASPGTAASENDSSVSPSFANEVKKED
VYSAHHSIS------LEA-------ASPGLAASTQDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------IERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENMLEASISLSEPLMLEEPE
KEEIETSLPIAITPEPEDSNLVE-EGIIELDYPEGPLVSEKPFPPHV-SPELEH------
------------------------------------------------------------
---------------KEEELILPLLTTS-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELQE----REG------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAAPASEL--------------------------------------SLSPFTTEKTSES
QSPLFSTVTPEHMVLSGDEASES-----GCYTPDSTSAS--------------EYSVPSE
ATKESL--KKTTDRKSPLIS--KGVSEHMIPSEE-KEDTGSFTP---AMASASEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSERFTPDSKLISKYAAPLNATQESQKKI
IDEASQFKPKGISEHTVVSVEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
PSSPDL-VVASEHS-FPP--------HTTEMTSECQAPPL-----SATPSEYVVLSDEEA
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPMNLSEED--QEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEVELFSPDSAS--QVSVPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKAETFLLMSP--LEDLSLPPSTD--KS
EKAEIKPEIPTTSTSVSEYLILAQK-------QKAQAYL-EPESEDLIPPHIT-------
--------S---EVEKGEREAS-SSVAAIPA--SLPAQSPIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQELTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QV---KKMEPQPPN--
--VPGSEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSKNEP---EVIKPYSP
LKETSLSGP----------------------------EVLS----------AVQMEMKHD
SKITTTP----TVLHSASSGVEKQVE---------------------------------H
GPPA--------LAFSALS--EEIKKEIEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVDR-RVLTKVVK-------G
ESGSGLP----------------PL--VTSADEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLP
EVEAKEAKAGLPVIKTSSFQ------------------HSDESEEARVE------DKQDL
SFSTVRDSERLVSSQKKSLVSTSEVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSPPELENL-ASGLAPTLLLLSDDKNKQAVEVSSTAQGDFPSEKQDIALA
E-----LSLEPEKKDKPHQLSELPN---AGSEFSSDLGRQSGSIGTKQAKSPITETEDSV
LEKGPAELRSRE-GKEENRELYA--SSTM-PAISELSSLLREESQNEGIKPFSPKIVSLE
SKEPPASVAEGGNPEEFQPFTFSLKGLSEEVSHPADFKKGGNQEIGPLPPTGNLKAQVMG
DILDKLSEETGHPA--PSRVLQSITEPSKIAPSDLLVEQKKTEK----ALHSDQTVKLPD
VS-----TSFEDKQDLGIKQFSFMRENLPLEQSKSFMTTKPADVKETKMEEFFISPKG-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPGQLKAAV----------------
-SSEDHTYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSSKSYSSEEVKL-AEEP
KSLVLAGNVERNIAEGKEIHALMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFFQ-
KPVSGLSVEQVKSETISSSVKTAHFPAEGVEPAL-GN---EKGAH-RSTPPFPEGKPLEE
SKMVQSKVIDDADE-----GKKPAPEV-KIPTQRKP-ISSIHA--KEPQSPESLEVTQKP
PTQPKVA-KPDLPEEKRKRGISSFKSWMSSLFFGSSTPDNKVAEQ-EDL-ETQPSPSVEK
AVTVI-EPKGTI---P-TNFNAAEKPADHSLSEVKLKTADEPRGTLVKSGEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISGDSEEMNINSVVTSADDE-NLEIQPSSL
IGEKLVMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKGEPR--S
DQ-----------------------------------------------------KQKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKPESIILPVEESKGSLID
LSEDRLKKEMQNPTSLKISEEETKLRSVSPTDKKDNLENRSYTLAEKKVLAEKQNSV-AP
LELRDSNEIGKTQITHGSRSTEPEESKADAMPQHFYQN-EDYNERPQIIVGSE----KEK
GE---EKENQVYVLSEGKKQQEHQPYSVNVAESMIKESDI------------------S-
--LGHCLG-E-----TQSFSLVKAMSVTEKSEA---------------------------
-----MLSEAHPEIREAKAVGTQPHPLEESKVSVEKTKTFLP--------VALSCHDEIE
NHSLSQEGNLVLE-----------------------------------------------
-------------------------------------------KSSRDMPDHSEEKEQ-F
RESELSKSGSVDITKESMKQG----------FPSKESERTLARPFDETKSSATPPYLLSS
VKP-----QTLASGASPEINAVKEQEMPQSEL-----------TPE--------------
---------RHTVHTIQTSKDDTS-----DVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----SNTSASNADKMVSNKEMPKEPEDTYAKDEDF-------TVTSKP
AGL---AEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASFKTI-
PLPDDSETVACHKTLK-SRL---EDE--KVTPLKE-HKQKETH---------KTKEEMST
DSETGDLSFTQPTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEEKLSKEI
TEETISFPGSSVESALEHEYDLV-KLDESFYGPEKGHDIL-SHPETQS----QNSAD--R
NVS-KDTKRDVDSKSPGMPLFEAEEGVLSRTQIFPTTIKVVNPELLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGKDDSCQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVSGEGASVDH
VETTGNVV-MQKKAPITEDVRVATQK-ISYAVPFEDTHHVLERADEA-------------
-------GSQG------NE------VG---------NASPEVNLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILVPPEPSEE--RLRNSPVQDEYEFAESLRNEVVPQ-DILSEE-LS
SESTPEDVL-SQGKESFEHIS--ENEFVSEAEQSTSAEQKELGSERKEENQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDRAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----SFE--------EINER
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKEDVIDSFQVYCMEEPQDDQEV--NELVEEYRLTVKESYCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEAT
ETYTLEYCRQHSPEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAVQ-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYNNQRLIFINAESGQLLFIVRHRFNESVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASRDSN-----
--HAGESFLGS-------RRDEEATRELETEEESE----GEEDEA----AAESEEEPDA-
-RLSDQDEEGKIKQECIISDPSFSMVTVQREDSGITWETNSSRSSTPWASEESQTSGVCS
REGSTV-NSPPGNVSFIVDEVKKVRKRTHK--SKHGSPS--LRRKGNKKRNSFESQ-DVP
TNKKGSPLTSASQILTTEKEKSYT---GVYDKARK----KKTPSNTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIKEIHYRKGKD--ASISLEPDL
DNSDSNTVSKTSKL-----VAQSIED-----------------KVKEVAPPWRGSISKG-
----------SESLT---------SMFSHEDQ-KKICADSPLNAT--SALE---------
-----------------HTVPSYSSSDRAE---QGIQLRHSQSV----------PQQPED
EAKPHEVEPPSVTPG-TPATVF--LRTAKEECELASPGTAASENDSSVSPSFTNEVKKED
VCSAHHSIS------LEA-------ALPDLAASTEDG----LDPDQEQPDLTS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LERAEPVSA------------
--KLTPT-----------HPSV-------------KGEKEENVLEPSISLSEPLMLEEPE
KEEIDTSLPVAATPEPEDSNLVE-EEIIELDYPESPLVSEKPFPPHM-SPEVEH------
------------------------------------------------------------
---------------EEEALILPLLATS-------------TPEHVALSEEERE----EI
ASVSTDSAFVSEYSVP----------QDLNHELEK----RES------------------
----------------EPVSPSNVEAIAEHAVLS---------------EEENEEFEAYS
PAAASASER--------------------------------------SLSPSTTEMTLES
QSPLFSTVTPEHMVLSGDEASES-----GRYTPDSTSAS--------------EYSVPSQ
ATKESL--KKVIDHKSPLIS--KGVSEHMIPSEE-KEDTGSFTL---AVTSAAEPSLSPS
TTEKTSECQSPLPST-ATSEHVVPSEGED-LGSECFTPDSKLISKYAAPLNATQEPQKKI
IDAASQFKLKGISEHTVLSVEG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KEDIG
PASPDS-VVASEHS-FPP--------HTTEVTSECQAPPL-----SATPSEYVVLSDEET
V-----ELERYTPSST---------SAS-EFSVPPYATPEAQEEEIVHR-SLNLK-----
------------------------------------------------------------
----GASSPTNLSEED--QEDIGPFSPDSAFASEFSFPPYATQEAEKREFECDSPICLTS
PSEHTILSDEDTEEAELFSPDSAS--QVSIPPFRISETEKNELEPDSLLTAVSASGYSCF
SEADEEDI-GSTAA---TPV-SEQFS--SSQKQKSETFPLISP--LEDLSLPPSTD--KS
EKAEIKPDIPTTSTSVSEYLILAQK-------QKTQAYL-EPESEDLIPPHLT-------
--------S---EVKKGEREAS-SSVTAIPA--SLPAQSSIVKEETKPASP---HSVLPD
SV-------------------PAIKKEQEPTAALTLK---------AADEQM--------
-ALSKVR---------------KEEIVPDSQEATAHVS------QD---QKMEPQPPN--
--IPGFEMKYSVLPDV-VD-----------------------------------------
-------------------EPKKGVKPKLVLNVTS--ELEQRKLSENEP---EVIKPCSP
LKETSLSGP----------------------------EVLS----------AAKMEMKHD
SKITTTP----TVLHSASSGVEKQVK---------------------------------H
GPHA--------LAFSALS--EEIKKEMEPSSSTTTAS-VTK---------LDS------
------------------------------------------------------------
---------------------------------------NLTKVVKEEISTDS-------
-----------------------------------SLVTPVGH-PVLTKVGK-------G
ELGSGLP----------------PL--VISTDEHSVL-AEEDKVA---------------
---IK-GASPIETS-SKHLAW--SEAE-----KEIK-------FDSPPSVSSIAEHSVLS
EVEAKEVKAGLPVIKTSSSQ------------------YSDESEEARVE------DKQGL
SCSTVRDSERLVSSQKKSLVSTSEVLGPEHELSLSLWGEIKKEETELPSSQNVSPASKHI
IPKGKDEEIASSSPELENS-ASGLAPTLLLLSDDKNKQAVEVSSTDQGDFPSEKQDIALA
E-----LSLEPEKKNKPHQLLELPN---AGSEFASGLGRQSGSIGTKQAKSPITETGDSV
LEKGPAELRSRE-GKEENRELYA--SATM-PTTSELSSLLREESQNEETKPFSPKIVSLE
LKEPPASVAEGDNPEEFQPFTFSLKGLSEEVSHPANFKKGGNQEIGPLPPTGNLKAQVMG
DIVAKLSEETGHPD--SSQLLQSVTEPSKIALSDLLVEQKKTEK----ALHSDQTIKLAD
VS-----TSFADKQDLDIKQFSFMKENLPLEQSKSFMTTKPADVKETKMEEFFISPKD-E
NWMLGKPENV-ASQHEERIAGSVQLDSSGS--NELRPEQLKAAV----------------
-SSMDHIYEVRKQVLPHSAEESHLSSQEAVSALDTSSGNVETLSCKSYSSEELKL-AEEP
KSFVLAGNVERNIAEEKESHSLMESESLLLEKANTEFSWPSKE-DSQEKIKLPPERFLQ-
KPVSGLSVEQVKSETIPSSVKTTHFLAEGVEPAL-GN---EKEAH-RSTPPFSGEKPLEE
SKMVQLKVIDDADE-----EKKPAPEV-KIPTQRKP-ISSLHS--EEPQSPESPEVTEKP
PTQPKVA-KPDLPQEKGKKGISSFKSWMSSLFFGSSTPDRKVAEQ-EDL-ETLPSPSVEK
AVTVI-EREGTI---P-TNFSVAEKQADHSLSEVKLKTADESRGTLVKSGEGQNVK-EKS
IILSNVEDLQQPKSI---SEVSREDYGKKEISDNSEEMNINSVVTSADGEKHLEIQPYSL
IGEKLIMEEAKTIVPLHVTDSKRVQKP------------AIAPPSKWNISIFKEEPR--S
DQ-----------------------------------------------------KEKSL
LSFDVVDKVPQQPKSASSNFASKNI------------TKESEKSESIILPVEESKGSLVD
LSKDRLKKEMQNPTSLKISEEETKLRSVSPTETKDNLENRSYTLAEKKVLAEKQDSV-AP
LELRDSNEIGKTQITHGSRSTELEESKANAMPQHFYQN-EDYSERPKIIVGSE----KEK
GE---EKENQVYVLSEEKKKQEHQPYSVNVAESMIKESDI------------------S-
--LGHSLG-E-----TQSFSLVKATSVTEKSDA---------------------------
-----MLSDAHPEIREAKAVATQPHPLEESKVLVEKTKTFLP--------VALPCRDEIE
NHSLSQEGNLVLEK----------------------------------------------
--------------------------------------------SSRDMPDHSEEKEQ-F
RESELSKGGSVDITKESMKQG----------FPTKESERTLAYPFDETKSSETPPYLLSS
VKP-----QTLVSGASPEINAMKKQEMPQSEL-----------TPE--------------
---------RHTVHTLQTSKDDTF-----DVPKQSVLVSK----HHLEAVEDTHVKEPLS
SAKSNYA-QFI-----YSASASNADKMVSNKEMSKEPEDTYAKGEDF-------TVTSKP
AGL---SEDQKTAFSIISEGCEILNIHAPAFISSIDQEESEQMQDKLEYLEEKASLKTV-
PLRDDSETVACHKTLK-SRL---EDSDEKVTSLKE-TKQKETH---------HTEEKTST
DSETGDLSFIQSTI----PS-EEDYFEKYTLIDYNISPDPEKQKAPQKLN-VEDKLSEEV
TEEAISFPVSSVESALEHEYGLV-KLDESFYGPEKDHDIL-SHPETQKSL-----AD--R
NVS-KDVKRDVDSKSLGMPLFEAEEGVLSRTQIFPTTIKAINPELLEEPPALAFLYKDLY
EEAVGEKKKEEETASEGDSVNSEASFPSRNSDTDDGTGIYFEKYILKDDILHDTSLTQKD
QGQGLEEKRVGRDDSYQPIAA--EGEIW---GKFGTICREKSLE-EQ-KGVYGEGESVGH
VETLGNIA-MQKKAPIREDIRVATQK-ISYAVPFEDTHHVLEHADEA-------------
-------GSQG------NE------VE---------NASPEVSLNVPVQVSFPEE-EFAS
GATHVQETPLEEPKILVPPEPSEE--RLRSSPVQDEYEFAESLHYEVLPQ-DILSEE-LS
SESRPEDVL-SQGKESFEHIS--ENEFVSETEQSTSAEQKELGSEWKEENQLSSE-LVTE
KAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKM
EFLHEQMVHFLQSMDTAKDTLETIVREAEELDE--AVFLT----VSL--------YSPDR
LLSAMESTASLEKMPAAFSLFEHYDDSSARSDQ-MLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSMNKDDVVDSFQVYCMEEPQDDQEV--NELVRRSQLTLT---AYFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTT--PEDT
ETYTLEYCRQHSSEG-EGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAAL
ISTR--GTRFLLLRETAHPALHISSSGTVISFAERRRLTEIPSVLGEELPSCGQHYWETT
VTDCPAYRLGICSSSAMR-AGALGQGETSWYMHCSEPQR---YTFFYSGIVSD---VHVT
ERPARVGILLDYSNQRLIFINAESGQLLFLIRHRFNEGVHPAFALEKPGKCTLHLGIEPP
DSVRHK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LSDQDEEGTTRQDCIVSDPSFSMVAVQREDSGITWETHSSGSSTPWASEGSQTSGVYS
PEGSTV-SSPPGNVSFVMGEVKKGRKRAHK--SKPGSPS--LRRKGGRKRNSDPQ--AVP
AHNRDSALVSGS--LSPKKEQSPA---GIYDKTRK----K-TTSSTPPITGAIYKEHKPL
VLRPVYIGTVQYKIKMFNSVKEELIPLQFYGTLPKGYVIQEIHYRKGKE--ASIRLEPDL
GDRDASRASPTATV-----AARSLAGD----------------SVREPSPPWRGALSKR-
----------PSALA---------SLTAQEDQ-KDRLVDSAHTAP---------------
--------------------------------------GAPPAV----------PQQPAA
K----ELSPPALG-------PLVSLEPAGHELEPVSPGAAASK-GSKAWPSPLEEVQAAG
------------------RIPSPGAGPPGLALAPLEA----AAPDEDRLDLASPEKAAPV
PEQWTPPHATVE------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------AEPAGRAP-------EPPAWEGAE
KEEPEPSRPTAA-------SAKD-SDLVELDYPESPLPGEGPFPPRR-PAELEP------
------------------------------------------------------------
---------------QDEEPGPPAPAAS-------------SEDRAGLPREPLE--PQDE
EPGPPAPAASSDLNII----------PYSSSILAEHLKHITTSLMFPNNWKIIWLQQENY
SGRCALSCQSSRGRRDSHRSPRGARARKPRLLLPERKAAASSSRRERGPQDSESPLSPLS
PTASSAAESG----RCS-----PQASPASDDLR-SAG---AASAPEPPVSTLAAERTPER
L-PPPPTAASQHLGPSGGD-RGR-----ERVTPDSKLAS--------------EHAVPPD
AAQESR--KEAIGDVPQLRS--KGVPEPTVPSDGEKEEAGPHPPPPPPAASVSEHILPPP
TPERTPELQPPLPPTA-TVEFKVSP-----GEGPGVTPDSKHIFKHAVLPSTTEESQKEI
IEDISQLQSKGVPEPTVPSEEE-KEEAGPPPPPAASV-----------------------
------------------------------------------------------------
----------------------------------------------------SEVSPG-E
GSGSERVTPDSKHIFKHAVLPNISQESQ-KDIIHDVSQLRSKGISEHTILSGE-EKEDAR
PQPQPV-ASESELP-LPP--------RTVEKTPECQAPLP-----AMPPAEHGVVLEGAP
V-----EGERYTPSS----------------------------REIICASPLNLK-----
------------------------------------------------------------
----GASSPEMFSEQE--RDDVGPFSPDSAFISEFSFPPSAVQDAERRELECGSPLYLTS
PSEHTVFSDEDTEEIDLFSPDSAS--QVSIPPYRSPGTEKTETEPYSRMPASSASSYPCF
SGTDEDDG-GSTAA---TPT-PEHLDSSPGQ----------NT--PEAVSLPPSTT--KA
EEAEIKPDAHVTSTPVSEYLVRMQQ-------QRSQAAL-EPESEELILSRLT---S---
------------ELEKGDVKTSW-SVATPP---LAPAQSSVGKEETRPVLPASQPSASLD
SA-------------------HATEEEQERQASLTLK---------AVNEQM--------
-ALQEVR---------------EKATVPDSQGATAQAS------QA---QKVEPQLPD--
--VLRSEMKPSALPDA-VE-----------------------------------------
-------------------EPKKEVKSSLAGSAASRPEPEQTVLSEGEA---AGINPPLP
LRETALSGH----------------------------EVSS----------GVKMEVKLD
SKAAGPP------------GTGKEGE---------------------------------E
GLPA--------PAFSALS--EEIKKEIEPRSSTATAP-LAK---------PDA------
------------------------------------------------------------
---------------------------------------NLTKLERDSG-----------
----------------------------------ASLATHMEG-VVPAQAGQ-------D
ALGGVSV-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------PPAKPETVPGPEHKLSLELGTGQKREEAEFHLLQNVSPAAQHA
VPKSEGEEMASY-SKVDVLASEDSALTFLTPT-----RALETSLAAQRGFLSENCDLVQA
E-----RSLEPEEEVRPQEAPELPE---PVSA--CTKGGDSGSVRAKQARSLVAEAVDSI
LEKSPAELRQRGED--ETRELLV--STVE-------------------------------
------------------------------------------------------------
---------------------------LSKAASSLHVEQEQPEK----ARHSDQVVGSPD
VG-----GSFVGREDLGTKRLLVMKESLPLEQSKSCVTTEPAGIKETKVKEPIISPGD-E
NRTLGKPENMASEQQE-GRQASVQLDSAEG--EDRM------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------AARLPADVRDPAW-GH---EQESR-GHAPPLPAEKLLEE
ARRVPPKVVGDADE-----EKAPAPAV-ETPPQRRP-LSPIPA-KEEPLPQDAPDEVQKL
PEQPKAA-EPAVPQEKGKRGISSFKSWMSSLFFGSSTQDTKVAE--KDV-ESLPSPSVVS
TGTVR-VPEGES---P-AERKAAGKPGAR------PAAAEGPREAMVTPGEGQGLK-DTL
TVLSKVEVSQQARSSPE----ASRELGREEAAPCPGEVDRNSTAPPAPGGDHVGIQPSSP
TPEKS----------APVTDSKRYQKP------------AISPPSKWTISVQ-EEPR--S
DQ-----------------------------------------------------KEKSL
FSFDVVSKAPQQPKPALSDVTSKNI------------MGESEKPEWIISPGEESKGRLAA
LGEGRRKEDLLESTSSGGLEEDIKLRSAGCTEEKGDLETRSYTLAEG------QETV-AL
TELREDKEPGKARVMHKTE-----ESKIPIPPTLIDQ-NGDHKESSRIAVGSE----EEK
GE---EKEKQ----------------QQQWARSVPEESDI------------------T-
--LVHSRG-E-----TEPFLVVKTASIIETPES---------------------------
-----VISEARPEIREAKAGGVPPHLLEESRVFGEKTQSFRP--------VDLPCRSEMD
NHSVAPEGDLVFEK--PGR-----------------------------------------
-----------------------------------------------GMAG-SEEKGQ-V
PPSEASEGGSVAVGKERAKPG----------ALFKDSQRALDHLSEDAKSLETP-LLPSP
LKP-----QTAASRESTDIHAVEKQDVPLSEW-----------TAE--------------
---------RHTVHTSQAR-DRAP-----DVPHQAVLISK----HHMVAVEDAHVSEPSS
PATSNYA-QFI-----SSASTASADKVAPAKETREEAEDA------F-------TVTSKP
AGL---SEDQKSAFIIISEGCEILNVHAPAFIPSADQEESEQLQDKLEYLQEKFPIKTT-
ALRDDNEAAAVHRTSK-SNL---EDSGRKLPSFKE-NEQNESY---------KTEEEIPT
ESEAGDLAFAQPTV----PS-EEDYFEKYTLIDYNISPDPERQKPPRKLN-VEEEPSKEA
AKEMISFPESSEETVLEQDYDLV-KLDESFYGPEKDHSKL-PHPEPQKPFVIQKSPD--E
DAA-KRLRRDAESRSPGMPLFDTEEGVLSRTQIFPTVAKAINPELLEQPPALAFLYKDLY
DEAVGERERDEETASEGDSVNSEASFPRR-SDADDATGMYFEKYLLRDDILHDTSVAQED
QGQGLEGEPIGEDESYHLIAA--EGEIW---GKSGTVLGKATLEGEQ-KAAYREGEAEGR
VETPGDAAVLPREAPVIETVSAATQK-VSYAIPFVDTRHTLAHVEGA-------------
-------ASQG------NE------AA---------HAGPESGLNVPEQVSFPEE-EPVS
GAAYAGEMPLEGPSVLVPTEPSQE--RLRNSPVQDEYPFAESVSYAVVGE-DISSQE-LC
SEAVPGDELPPQGQEALEPIS--ADTLMRETEQSSSARQEDWGREMTAQDQVSPE-SVTE
KAPKDLKKPQIDTYCYTCRSPISTLDKVAGTHKDHEVSTLDTAISAVKVQLAEFLENLQE
KSLRIEAFVSEIESFFNTIEENCSKNEKLLEEQNEQMMKKVLAQYDEKAQSFEEVKRRKM
GFLHDQMVRFLQSMDTAKDTLESIVREAEGLDE--AVFLSFPPKSFE--------EINER
LLSAMESTASLENVPAAFSLFEHYEDSSARSDQ-VLKQVAVPQPPRLEPQEPNSATSTT-
-IAVYWSRNKEDTIDSFQVYCMEGPQDDQDI--NELVEEYRLTVKESCCIFEDLEPDRCY
QVWVMA----VNFTGCSLPSERAIFRTAPSTPVLRAEDCTVCWSTATIRWRPTS--PEAA
DTYTLEYCRQHCAEG-EGLRSFSGIKGLQLRVNLQPNDSYFFYVRASNAFGTSEQSEAAL
ISTR--GTRFLLLRDTAHPALQISADGTVISFAERRRLTEIPSVLGEELPACGQHYWEAT
VTDCPAYRLGICAGSAVR-AGTLGQGDTSWYMHCSEPQR---YTFFCSGVVSD---VHVT
EHPARVGILLDYSSQRLVFVNAASGQVLFMARHSFTEGVHPAFALEKPGQCTLHLGVEPP
DSVRHK

Query Results

"ENSGT00840000129812_2"

ENSGT00840000129812_2