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Query Results 

"ENSGT00780000121909_0"


Found:

ENSGT00780000121909_0


MGP_PahariEiJ_P0025938 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
ETLSQAGAG------SG--PSVAKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASCEAYEDLMKKSQEGKDFYADLESKVATLLERAQSICRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK-----APPPRPTAPKPLLSRREEGEA-VEA--------
-------GDPPEELRSLPPDMMVGPR-----------LPDPFLGT---------------
------------TVPLHFSPGTFPSSTGPATHY----LSGPLPPGTYSGPTQLMQPRAA-
----------------------------LPMAPATVPYPAP---AYTSELGLVPRSSPQH
GIVSGPYAGVGPPQP---------------------------------VVGLPSAPPPQL
S---GPELAMAVRPATTTVDSVQAPISSHTAPRPNPTPAL---------PQPCFPVPQPV
PQSVPQPQPLPAPYTYSIGTKQPLPAPYTY-SIGTKQ-HLTGPL--PQHQFPP-------
-------------------GISTGFPVPRTGPQPQPQPQPQ-------------------
-------PQPQPQPQPQPQRPAFGPQPTQQPLPFQHPHLFPSQAPGILPPP--PP-----
----------------------------------YHFTPQP-AV-----LGQPQPTLH--
------------T-------QLYPGPSQDPLPPHSGAL-----PFPSPGPPHP----HPT
LTYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPSRPPAAE------------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQQLQQELEAFRG
QL----------GDAGALDAIWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSVALSSIRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLKFCHEALVRHVEQVLQRHGVPPPGKPVATVNIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAAILPGL
VEA---------PGLPPASLP-ESTPVP----------------------------SSSP
PPLSSPLPEAPQPEEEP----S-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSMAUP00000023896 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKS----VAHEDIKYEQSCILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKSLVQSMQVLSGVFTDVEASLKDIRDLLEEDELHEQKLQ
ETLGQVLAA------PG--ASVAKAELAEVRREWAKYMGVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LGEVDQKWNSTLQTLVASCEAYEDLMKKSQEGKDFYADLESKVAALLERTQSLCRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
ATRQQLLDREL--------KKK-----APPPRPTAPKPSLSRREEAEA-VET--------
-------GDPPEELRSLPPDMVVGSR-----------LPDPFLGS---------------
------------PAPLHFPPGPFP--------Y----LSGPLPPGTYSGPTQPMQPRAP-
----------------------------VPMAPGTVLYPAP---TYTSELGLVPRSSPQH
GVVSSPYVGVGPPPP---------------------------------VVGLPSAPPPQF
A---GPELAMAVRPATTTVDSVQAPISSHTAPRPNRAPAP---------PQPCFPVPQPV
PQA------------------QPLPAPYTF-SLGTKQ-HVTGPP--PQHHFPP-------
-------------------GVPAGFPAPRIGLQAQPQ-----------------------
-------------PQPQPPQPAFGPQPPPQPLPFQPTHLFPSQAPGIIPPP-PPP-----
----------------------------------YPFTPQPSG------LGQPLPALH--
------------S-------QLYPGSSQDPLPPHSGAL-----PFPSAGPPHP----HPT
LAYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPAP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQQLQQELETFRG
QL----------GDAGALDIIWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSVALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGVPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEALVRHVEQVLQRHGVPPPGKPVAS--VS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDPPAASLPGL
VEP---------PGLPPASLP-EPTPVP----------------------------SSSP
PPLSSPLPEAPQPEEEP----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSODEP00000017802 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFSFQAAVKKFVLKNFGENPEAYNEELKKLELLRQNAIRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAVDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPATASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREVMAKIEDKNEVLDQFMDSMQLDPETVDNLDTY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRTLLEEDELQEQKLQ
EATGQTGAS------LA----TAKAELAEVRKEWTKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTDANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSACQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK------PPPRPTAPKPLLSRREESEA-SET--------
-------GDLPEELRSLPPDVVAGPR-----------LPDAFLGA---------------
------------TPPLHFTPGPFSSPTVPGPHY----VPGTLPPGTYSGP----------
------------------P--------AVPVVPSPVLYPAP---TYTPELGIVPRSSPQH
GMGSSPYGAVGVPHA---------------------------------AAGLPSAPPPQF
S---GPELAGTVRPATTTVDSVQAPISSHLALRPSPGST----------PQPCFPSQPPQ
------------------------PVPYTY-PVGTKQ-PL--------------------
------------------------------------------------------------
-----------PASPPHPSRAAFGPLPPQQPLPFQHPHVFPPQAPGVL--PSQPP-----
----------------------------------YPYPPRPSVL------PQPPTAL---
------------------RAPLYPGPAPEAMQPRVGAL-----PFASSGPPQ---PPHPS
LAYG-PGPS--PRPLG----VQAPPVPM-------------------HGPPPAGQLSPNP
HLV-PSPAPSPGP----GPAPPRPPPTDP-----------PACPR--R------DLLSSS
PESQHGGVQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLGRLQQELEAFRG
QL----------GDAGTLDAVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSETE
MEK-------------------------QKVARYFPTERSQPMVHGALSVALSSVRATET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHTHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPALPQLVRRMRQQRK
HMLQE----KLHLKFCHEAVVRHVEQVLQRHGVPPPCKPLASVGTG--------------
------------TNQKLPQDSQDLVLGGDVPISSIQATIAKLSIRPAAGMDSPATMQADT
AES---------LGLAPASLPEPTS-------------------------------APSS
PPPLSPLPEAPQPEEHQ----P-APE---------PPSAGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQSFLQAHSGQGLR-SARAPDDPLSLLDPLWTLNKT-
ENSACAP00000000753 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------Q
PF03097 // ENSGT00780000121909_0_Domain_6 (618, 748)
VVYFQSALDK----------LNEAIKLAKGQPETVQEALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQSVK---GAPLVKALPVNPTDPTVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREVMAKIEAKNEVLEQFMDSLQLDPETVDNLDMY
NHIPPVLMEKCAALSVRPETVKNLVQSMQVLSGVFTDVEASLREIKDLLDEDEAQEQKQR
ETLGKTAAPQQQDSPPATAPSSSSSGLAEVAKEWAKYMEVHEKASFTNTELHKAMNLHIS
NLRLLSGPLEQVRAALPSPSLTEEDQQ-VMQNLKRILSKVQEMKDQRVSLEQQLREMIQK
DDITTSLVTTDRSEMKKLFEEQLKKYDQIKVYLEQNLAAQ-ENILKALTEANVKYATVRK
A-LSEVEHKWNTTLQSLVASYEAYEDLMKKSQEGKDFYADLESKVAKLLEKGRVACKAAE
AARQQALAKEA--------------KLRPPPRPTTPKPPLQKKPTDPEGVEMMP------
ALASLSLADLPEELRSLPPEVLASHLAQLPPDALAALGMDPAFACAGFGGAG---PEAFG
VTPLPPPRAS--QAQAPFSPGHFMA--------------GGPMPGQYQPPRALTVAP-GQ
RP--------------------------FPRVPAPGPFPSHQMPPPMPRAGLPPLSSAPS
AVP-SAQ---------------------------------LPGGPPAPPAHLPPAHPHNF
GAHHFPSQAQVVRPATTTVDSIAPSP-AAPAPREIPGPAP------------QWAAPPLL
PPS----------------SPAKLSGPTFMPPAGDSL-LLS-----AQSHPKARFFLPPK
PSPPNKATSRAPSLPQAS--VP--------------------------------------
-------STVLS----------QGPV--H------------PAVQGQ----------IPR
QMPPPALPAARQNA-PS--------------------------------NG---------
-------------APSPLRDHGLPDPGPQGLQHHGGP----GGAWPAPAPPM---PPAAQ
GAYGPGPAIAAPLPPGPQQ------QPPPPPPSPGLTQMPGGVVVPGPA-----------
---LPSPAPSPQP------QPPMPPSSLQ-------GPSETPFHRQGSSSSTTDDLLSSS
PESQHGGPK-AAVGQPLLQPTKADAKDGLRPKAVQLIENDPYEKPERLRRLLSELERFQE
AVAALGRPGP---GGTELDGLWKELQEAQEKDARQRSIAIARCYA
PF00102 // ENSGT00780000121909_0_Domain_8 (1966, 2241)
MKNRHQDIMPYDKNR
VVLQSGKDDYINASRIEDLSSYCPTIIATQAPLVGTASDFWLMIYEQKVSVVVMLVSEQE
IEK-------------------------QKVLRYFPTERGQPMVQGPITLVLTSQKATPT
HTERMISLQFRDQSLKRTIIHLQFFSW-PELGLPD-SKGVLLRFIQEVHSHYLHQRPLHM
PIVVH---------C----SSGVGRSGAFCLLYAAMQEVEAGNSIPDLARMVKRIRQQRK
HMLQE----KLHLKFCFEAVLKHAKQVLQRHGVIAASAGKPPSSTA--------------
----------GPQKPYVHQDPQDLVLGGDMPISSIQATIAKLSIRPPSGGAEAPAANGQP
PTEPSMTNAGALPAASH-------------------------------------------
-------PTAPDPAVSVAPEQPPPPPLS-PPTAVAASAAAPSSSSLELLASLTPEAFTLD
SALKGRQRVSKQSFLQPQNGEGLR-GARPSDDPLSLLDPLWTLNKT-
ENSMOCP00000011024 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPETASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
ETLGQTGAA------PG--PSVAKAELVEVRREWTKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSICRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK-----APPPRPTAPKPLLSRRDEGEA-VEA--------
-------GDPPEELRSLPPDMVVGSR-----------LPDPFLGT---------------
------------TAPLHFSPGPFPSSTGPAAHY----LSAPLPPGTYSGPTQLMQPRAA-
----------------------------VPMAPGTVLYPAP---TYTSELGLVPRSSPQH
GVVSSPYRGVGPPPP---------------------------------VVGLPSAPPPQY
S---GPELAMAVRPATTTVDSVQAPISSHAAPRPNPTPAL---------PQPCFPVPQPV
SQPIPQPQPLPAPY--------------AF-PVGTKQ-HLTGPP--PQHHFPP-------
-------------------GVPTGFPAPRIGPQAQP------------------------
--------------QPQPPQPAFGPQPSHQPLPFQHPHLFPTQAPGILPPPP-PP-----
----------------------------------YPFNPQPAAV-----LGQPPPTLH--
------------S-------QIYPVPSQDPLPPHSGAL-----PFPSPGPPHP----HPT
LTYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQQELETFRG
QL----------GDAGALDAIWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSVALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEALVRHVEQVLQRHGVPPPGKPVAS--IS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGVDSPAASLPGL
VEP---------PGLPPASLP-EPTPVP----------------------------SSSP
PPLSSPLPEAPQPEEEP----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSMLUP00000014180 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 750)
-MIWLD------------------
---LKEAGDFLFQAAVKKFVLKNYGENPDAYSEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIQYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGEQVA------
--------------Y-----FQSALDK----------LSEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREIMAKIEDKNEVLDQFMDSMQLDPETVDNLDTY
NHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLDQKLQ
EAVGQAGAS------VA----GSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDQA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDRSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
A-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQARE
AARQQLLDREL--------KKK------PPPRPTAPKPLLPRREEGEA-GEM--------
-------GDPPEELRSLPD---------------------AFLGA---------------
------------AATLRLAPVPFPGSAGPGPHY----LSGPLPPGSYSGPTQVMQPRGPQ
APGP--------------P--------VMAMAPGPPIYAAP---VYTPELGLVPRSSPQH
GVVGTPYGAIGPHPP---------------------------------AAGLPSAPPPQF
S---GPELAMGVRPATTTVDSVQAPISSHTAPRPSPSCSS----------QALLPSTPTP
---------------------ATVHAPIIW-ELSS-------PS--QQHQPNTTILI---
-------------------GSLRGFQPQGKGLSPSVI--------------PHGQKLGPS
-------------PHRTPP-----RISSSSPLHLQKPKHLPNHVPGRLSHMTRFT-----
----------------------------------WHHKPCLGETAMPLCYGHDQGPLLTA
CPGILGLSHGLSLSPSQKNDQRFQGPPFFSVTPKNGPMLSLSAPFLNENXWAP--SAPHS
PGYG-PAPS--PA-LG----RRQPLSPF-------------------KAPSPASQATPSP
HLV-PSPAPSPGP----GPVPPRPPAADP-----------PPCLR--RGTV-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYERPERLQQLQQELEAFRG
QL----------GDAGALDAVWRELQDAQEHDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YSLKNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGLPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQ-LQRHGVPPPCRPLAGTGVS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSPVACLPGP
VEP---------PGLLPASLPQ-STQLP----------------------------SSSP
PPLSSPLPETPQPEEEQ----P-VPE---------VPSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLHAHNGQGLR-AAPPADDPLSLLDPLWTLN---
ENSFCAP00000014352 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MEAV-------PRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFLFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPVLDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRELLEEDELLEQKLQ
ETLGQAGAS------LA-GGAGSKAELAEVRRDWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEIKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSDLDQKWKSTLQTLVASCEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDRWG--------AEEE-----ATPRPTAPKPLLPRREEGEA-VET--------
-------ADLPEELRSLPPDMVAGPR-----------PPDTYLGA---------------
------------AAPLHFPPGPFPSVAGPGPHY----LSGPLPPGTYSGHT--------Q
APGH--------------P--------AMAMAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSGPYAGVGPPPP---------------------------------VAGLPSAPPPQF
S---GPELAMGVRPATTTVDSIQAPISSHTAPRPNPSPAP---------PQPCFPVSPPQ
--------------------PQLLPAPYTY-PLGT-KQPLTAPP--AQHHFP--------
-------P-----------GIPPGFPAPR--VG----------------PQPQPQPQPQ-
-----------PQPQPHPTGVAFGPQPPQQPLPLQHPNLFPPQAPGRPSQPPQPP-----
----------------------------------YPFTPQPGV------LGQPTPPLH--
------------T-------QLYPGPSQDPLPPHSGAL-----PFPSPGPPQ---SPHPT
LAYG-PAPS--SRPLG----PQAAPLSI-------------------RGPSPAGQPPPNP
HLV-PSPAPSPGP----GPVPPQPPAAEP-----------PPCAR--RGTA-TADLLSSS
PESQHGGAQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYERPERLQQLQQELEAFRG
QL----------GDAGALDAVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRATET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PVIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPRLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPGRAPAGTGSS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPAGGLDSPAAGLPAP
VEP---------PGLPPASLPE-SAQLP----------------------------SSSP
PPLSSPLPEVPQPEEEQ----P-APA---------PPSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSMPUP00000014910 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------
PF03097 // ENSGT00780000121909_0_Domain_4 (406, 748)
YEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILSLNVNLMLLL
A-----------------------QGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVMGLQEEG
RMHQALPTAPPQVTY-----FQSALDK----------LNEA-------------------
---------IKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NHIPPQLMEKCAALSVRPDTVRNLVQSM---QGVFTDVEASLKDIRELLEEDELLEQKLQ
EALGQAGAS------PA----GSKAELAEVRRDWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTADHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQARE
AARQQLLDSIQ--------ATIAKLSIRPPGALDSPAAS---------------------
-----------------------------------------IPGP---------------
------------VEPPGLPPVSLPESTQL-------------PPS---SPPPLSSPQP-E
AP----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------
ENSPPAP00000039642 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKYNSAKKDNDFIYHEAVPALDTLQPVK----APLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAI------S----ITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALSPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-VEA--------
-------GDPPEELHSLTPDMVAGPR-----------LPDTFLGS---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------P--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGFPSAPPPQF
S---GPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAP---------PPPCFPVPPP-
---------------------QPLPTPYTY-PAGAKQ-PIPA-----QHHFSS-------
-------------------GIPAGFPAPRI--G----------------PQPQP----H-
-------------PQPH-PSQAFGPQPPQQPLPLQHPHLFPPRAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPPPLX--
------------XXXXXXNIYLGSGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PATS--TRPMG----PQAAPLTI-------------------RGPSSAGQSTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLCFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PHLSSPLPEAPQPKEEP----P-L---------------GAPSSSLELLASLTPEAFSLD
SSLRGKQRMSKHNFLQAHNGQGLR-ATRPSDDPLSLLDPLWTLNKT-
ENSDNOP00000019056 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 748)
-MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVSVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNDAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHESVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDMY
NHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLDQKFQ
EAVGQAGAN------PA----APKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALSAEDKA-VLQNLKRILGKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLDRAQSACQARE
AARQQLLDREL---------KKK-----PPPRPTAPKPLLPRREEGEA-VET--------
--------DPPEELRSLPPDMVAGPR-----------PPDTFLGP---------------
------------AAPLHFPPGPFPSSAGPAPHY----LPGTLPPSTYSAPPQLLQPGPPQ
APGH--------------P--------AMAMAPGTALYAAP---AYTPELGLVPRSSPQH
SVVSSPYGGVGPPQP---------------------------------VAGLPSAPPPQF
S---GPELAIGVRLATTTVDSVQAPISSHTAPRPNPTPVP---------PQPCFPVPPPQ
--------------------PL--ATAYAY-PLGTKQ----ALP--AQHRFP--------
-------P-----------RIPTGFPAPR--LG----------------HQPQPQP----
----------------HPSRATFGPQPPQQPLQLQHPHLFQPQPPAPL--PPQPP-----
----------------------------------FSFAPQPGV------LGQLPPPLH--
------------T-------QLYPGPSQDALPPHSGAL-----PFPSPGPSQAPQPPLPT
LAYG-PTPS--PRPLG----PQAAALSI-------------------RGPPPTSQPTPTP
HLV-PSPAPSPGP----GSVPPQPPSAEP-----------PPCLR--RGFA-AADLLSSS
PESQHGGSQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYERPERLRQLQQELEAFRG
QL----------GDAGTLDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVVRYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGHLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRHMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPCKPLASLSNS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPAGGLDVPAASLPGP
AEL---------PTQPPASLTE-STQVP----------------------------ASSP
PPPSSPQPEAPQPEEEL----L-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPADDPLSLLDPLWTLNKT-
ENSACAP00000020854 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------VCKLPRVPLGRWWRG------------------
---TKQQGDHILSFSSF
PF03097 // ENSGT00780000121909_0_Domain_4 (318, 739)
QFVLKNYGENPENYNEELKKLEQLRQNAVNVPRDFEGCSILRK
YFGQLHYLQSRIPMGAEHEAAVPITWTEIFSGKA----VTHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFTYLRDHFPHSYSVDMSHQILNLNINLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENSETASLLGKIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKYGERVV------
--------------Y-----FQSALDK----------LNEAIKLAKGQPETVQEALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQSVK---GAPLVKALPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYR-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------
ENSTTRP00000002133 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MEAV-------PRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 750)
-MIWLD------------------
---LKEAGDFHFQPAVKNFV-QKYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVSVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRMSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFTKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVAASLKDIRDLLEEDELLEQKMQ
EAVSQAGAS------TA----VSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEIKKLFEEQLKKYDQLRVYLEQNLAAQ-DNILRALTEANVQYASVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQARE
AARQQLLDREL---------KKK-----PPPRPTAPKPLLPRREEGEP-VEA--------
-------GDLPEELRSLPP--------------------DTFLGA---------------
------------AVPLHFPPGPFPSSAGPGPHY----LSGALPPGTYSGPAQMLQPRGPQ
ALGH--------------P--------VVAMAPGPALYTAG---AYTPELGLVPRSSPQH
GMVSSPYVGVRSAPP---------------------------------AAGLPSAPPPQF
S---GPELAVGIRPATTTVDSVQAPISSHTAPRPNPAPAP---------PRPRFPGPPPQ
--------------------P--LPVPYTY-PMGA-KPPLAAPP--AQHHFS--------
-------P-----------GMPTGFSAPR--TG----------------PQP--------
----------------HPTRAVFGPQPPQQPLPLQHPHLFPPQPSGLV--PPQTP-----
----------------------------------YPFAPQPGV------LGQPPPTLH--
------------T-------QLYPGPSQDPLPPHSGVL-----PFPSTGPPQ---PPHPT
LAYG-PAPS--PRPLG----PQAPALSI-------------------RGPPPASQPAPTP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------AVCLR--RGAA-SADLLSSS
PESQHGGAQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQQLQQELEAFRG
QL----------GDAGALDAIWRELQDAQEHDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YSLKNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGSGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVKHVEQVLQRHGMPLPCKPSAGTSVT--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDFPAAGLPGP
VEP---------PGLPPPSLPE-STQLP----------------------------SSSP
PPLSSPLPEAPPPEEEQ----P-VPE---------VPSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSBTAP00000003600 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------GAWLSLQ-----------------LRK
LGERPG--------------GRRVPAAMEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 748)
-MIWL-------------------
--DLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVSVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFSYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGEQVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSLQLDPETVDNLDAY
NHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDVRDLLEEDEALEQKLQ
EAVGPAAAS------TA----TSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPSPALSAEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITAVLVTADHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LGDLDQKWNSTLQSLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERTQSACQARE
ATRQQLLDREL--------KK------KPPPRPTAPKPLLPRREEGEA-MEA--------
-------GDLPEELRSLPPE--------------------PFLGA---------------
------------AAPLHFPPGPFPSSAGPGPHY----LSGALPPGTYAGPTHMLQPRAPQ
PPGH--------------P--------GVAVAPGPALYTAP---AYAPELGLVPRSSPQH
GMVSSPYGGVGPPPP---------------------------------LAGLPSAPPPHF
S---GHELVVGVRPATTTVDSVQAPISSHTAPRPNPAPAP---------PQACFPGPPP-
---------------------QPLPLPYTY-PMGPKQ-PLTLRE--ILTPSSGIILPVPR
NTYHQVTSARGGGMPGTQREVPEGWPRQADPLGHLQAALSQVCQHPQSRPVPHGPHILPS
RSRGPQSCKVLPPARGVPQDADVKESPLFSHQRLQHPHVFPPQAPGLV--PAQAS-----
----------------------------------YPFAPQPGV------LGQPSPALH--
------------T-------QLYPGPSQDPPPPHSGAL-----PFASAGPPQ---PPHPT
LAYG-PAPA--PRPLG----PQAAPLSI-------------------RGPPPAIQPAPTP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGTA-AADLLSSS
PESQHGGPQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYERPERLQQLRQELETFRG
QL----------GAAGALDTVWRELQDAQELDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSHLLRFIQEVHAHCLHQRPLHT
PVVVH---------C--SRSSGVGRTGAFALLYAAVQEVEAGSGIPQLPQLVRRMRQQRK
HMLQE----KLHLKFCHEAVVRHVEQVLQRHGVPPPSKPTAGTGIT--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGMDSPVASLPGP
VEP---------PSLPPPSLPE-STQLP----------------------------SSSP
PPPSSPLPEAPQPEEEQ----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
GSLRGKQRMSKQDFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSOGAP00000016953 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 748)
-MIWLD------------------
---LKEAGDFQFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAIPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAS------L----AVSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERVQSTCQARE
AARQQFLDREL--------KK------KPPPRPTAPKPLLARREEGET--EI--------
-------GDPPEELRSLPPDLVSGPR-----------PPDTFLGT---------------
------------VTPLHFPPG-------PGPHY----LSGPLPPGAYSGPSQMMQPRA--
-PGP--------------P--------TMPVAPGSALYPAS---AYTPELGLVPRSSPQH
GVVSSPYGGVGPPPP---------------------------------VAGLPSAPPPQF
S---GPELAVAVRPATTTVDSVQAPISSHTAPRPNPSPAP---------PQPCFPVPPP-
---------------------QPLPTPYSY-PIGAKQ-PLIAPP--AQHHFSP-------
-------------------GIPTGFPVPRI--G----------------PHPHP------
------------------SQAALGSQVP----QLQHPHLFPPQAPGLL--PPQPT-----
----------------------------------YPFAPQPGV------LGQPPPL-H--
------------T-------QLYPGPSQDPLPPHSGAL-----PFPSPGRPQ---PPHST
LAYG-TTTS--TRPLG----PQVAPLSI-------------------PGPSPVGQPNPSP
HLV-PSPAPSPGP----GPVLSRTPAAEP-----------PLSSR--RGTA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQEELEVFRG
QL----------GDIGALDTIWRELQDAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFTTW-PELGLPD-SPSNLLRFIQEVHTHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLKFCHEAVVRHVEQVLQRHGVPPPCKPVASST----------------
---------SLSQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSPAASQPGP
IEP---------PGLPPASLPE-PTPVP----------------------------SSSP
PPLSSPLPEVPQPEEEQ----P-VPE---------APNLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLN---
ENSSTOP00000014280 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MEAV-------PRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFLFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFTQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEILDQFMDSMQLDPERVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIKNLLEEDELQEQKLQ
EAVGQAGSS------PA----VTKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVS
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLEREL---------KKK-----PPPRPTAPKPLLPRREEGEA-VET--------
-------GDPPEELRSLPPDMMAGPR-----------LPDTFLGT---------------
------------ATPLRFPPGPFPSSTGPGPHY----LSGPLPPGTYSGPTQLMQPRA--
-SGP--------------P--------AMPMAPGPALYPAP---TYTPEMGLVPRSSPQH
GVVSSPYRGVGPP-P---------------------------------AVGLPSAPPPQF
S---GPELAMAVRPATTTVDSVQAPISSHAAPRPNPTPTP---------SQPCFPVPPSQ
--------------------P--LPPPYTY-PIGT-KPPLTAPP--SQHHFP--------
-------P-----------GIPTGFPAPR--IA----------------PQPQP------
----------------QPPQAAFGPQHPQQPLPFQHPHLFPPQASGLI--PAQPL-----
----------------------------------YPFTSQPGVS-----LGQPPPPMH--
------------T-------QLYPGPSQDPLPPHSGAL-----PFPSPGPPQ---PPHPT
LAYG-PAPS--PRPLG----PQAVPLSI-------------------RGPPPTGQPTPSP
HLV-PSPAPSPGP----GPVPSRPPAAEP-----------PPCLR--RGTA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELESFRG
QL----------GDAGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
IEK-------------------------QKVARYFPTERGQSMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHTHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLKFCHEAVVRHVEQVLQRHGVPPPCKTLASISIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSPAANVSGP
AEP---------PGPPPSSLPE-PTPIPV-------------------------PPPSSP
PPISSPLPEAPQPEEEQ----P-VAE---------TPSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSTSYP00000013758 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFQFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRLLLEEDELLEEKFQ
EAVGQAGAS------L----TVSKAELADVRREWTKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRKEEGEA-MEA--------
-------GDMPEELRSLPLDMVAGPR-----------PPDTFLGT---------------
------------AAPLRFPPGPFPGSTGPGPHY----LSGPLPPGTYSGPTQLMQPRA--
-PGP--------------P--------ALPMAPGPALYPAP---AYTPELALAPRSSPQH
GVVSSPYAGVGLPPP---------------------------------VAGLPSAPPPQL
S---GPELAMVVRPATTTVDSVQAPISSHMAPQPNPSPAPP--------PQPCFPMPPP-
---------------------QPLPTPYTY-PVGAKQ-PLPAPS--AQHQFSP-------
-------------------GLPTGFPAPRI--G----------------PQPQPHS----
------------------SRAAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQPP-----
----------------------------------YPFAPQPGV------LGQPPAPLH--
------------S-------QLYPGPSQDPLPPHSGAL-----PFPNPGPPQ---PPHPP
LAYG-PAPS--PRPLG----PQASLLSI-------------------RGPPPAGQPSPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAT-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDAGALDSIWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVLPPCKPSASTSISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPAASLPGP
TEL---------PGQPPASLPE-STPIP----------------------------SSSP
PPIPSPLPEAPQPEE-Q----P-VPE---------APTSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSJJAP00000023313 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQAAVKKSVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGEQVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1077)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEEELQEQNLQ
ETLGQAAAG------P----TVAKAELAEVKREWAKYMEVHEKASFTNSELHRAMNLHIG
NLRLLSGPLDQVRAALPTPALTPEDRA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSIC
ENSGT00780000121909_0_Linker_7_8 (1077, 1967)
RGQE
AARQQLLDREL--------KK------RPPPRPTAPKPLLARREEGEA-VEM--------
-------GEPPEELRSLPPDMVGVPR-----------LPDPFLGT---------------
------------SSQLHFPPGTFPSSSGPAPQY----LSGPLPPGTYSGPTQLVQPRA--
---------------------------TVPMAPGPAVYPAP---VYTPELGLVPRSSPQH
GVVNSPYGGVGPPTP---------------------------------VVGLPSAPPPQF
S---GPELAVVVRPATTTVDSIQAPISSHTAPRPSPSPAP---------PQPCFSVPPPA
PL------------------PQPVPAPYTY-SIGNRQ-HLPGPP--PQHHFPP-------
-------------------GISTGFPAPRLG-----------------------------
-----------PQPHPHPSRAAFGPQPPQQPLPFQHPHLFPSQAPGILP-PPPPP-----
----------------------------------YPFPPQPGV------LGQPPPPLH--
------------T-------PLYPGPSQDPVPPHSGAL-----PFPSPGPPP---PPHPP
LAYG-PAPT--PRPLV----SQAAPVSI-------------------RGPPSAAQPTPSP
HLV-PSPAPSPGPGSGPGPVPSRPPAAEP-----------PSCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAGEGRRPQALRLIERDPYERPERLRQLQQELETFRG
QL----------GDAAALDTVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPLLVATQAPLPGTAADFWLMVYEQKVSVIVMLVSEAE
VEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRCMRQQRK
HMLQE----KLHLRFCHEALVRHVEQVLQRHGMPLPGKPLASTSIN--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSPAASLPGP
AEP---------TGLPPANLPE-PTP-----------------------------DLSSP
PPLSPPLPEAPQPEEEP----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLM-AAQPTDDPLSLLDPLWTLNKS-
ENSMMUP00000018455 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQTGAT------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------A--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---SPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTAAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQP--------
--------------QPH-PSRAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YSYAPQPGV------LGQPPTPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--ARPVG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSMFAP00000045862 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALLCGG
G----PGSLFLFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQTGAT------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------A--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---SPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQP--------
--------------QPH-PSRAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YSYAPQPGV------LGQPPTPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--ARPVG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVVRYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSOCUP00000002733 (view gene)
M
PF07707 // ENSGT00780000121909_0_Domain_0 (2, 93)
MCAVLYDAANSFIHQHFVEVSMSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWV
RYDREQRGPYLPELLSSIRLPLCRPQFLSDRV
ENSGT00780000121909_0_Linker_0_1 (93, 133)
QQDDLVRCCHKCRDLVDEAKDYHLMPER
RPHLPAFRTRPR
PF01344 // ENSGT00780000121909_0_Domain_1 (133, 173)
CCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCHP
ENSGT00780000121909_0_Linker_1_2 (173, 177)
MTTA
PF07646 // ENSGT00780000121909_0_Domain_2 (177, 222)
RSRV
GVAVVN--GLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGS
ENSGT00780000121909_0_Linker_2_3 (222, 227)
MNSKR
PF07646 // ENSGT00780000121909_0_Domain_3 (227, 286)
SAMGTVVLDGQIYV
CGGYDG--------------NSSLN-SVETYSPET--DKWTVVTP
ENSGT00780000121909_0_Linker_3_4 (286, 315)
MSSNRSAAGVTVFEG
--RIYVSGGHDGLQ
PF03097 // ENSGT00780000121909_0_Domain_4 (315, 748)
IFNSFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLHSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
EAVGPAAAS------LA----VSKAELAEVRRECAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDLVRAALPSPALTPEDKA-VLQTLKRILAKVQEMREQRVSLEQQLRELIQK
DDITASLVTTDHSEMQKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVVALLERARSTCQARE
ATRQQLLDREL---------KKQ-----PPPRPTAPKPLLPRREEGEA-VEM--------
-------GDQPEELRSLPPDMVAGPR-----------PPDTFLGA---------------
------------ATQFHFTPSPFPRATGPGPHY----ISGPVPPGAYPSPTQLLQPRT--
-TGP--------------P--------AMPMAPGPALYPAP---AFTPELGLVPRSSPQH
GVVSGPYAGAGPPPP---------------------------------VAGLPSAPPPQF
S---GPELAMVVRPATTTVDSVQAPISSHAAPRPNPTPAPP--------PQPCFPM----
------------------------PPPYTY-PVGA-QQPLTLPP--AQHPFS--------
-------S-----------GIPAGFPAPR--IG----------------PQPPA------
------------------SRVAFGPQPAQQPLPLQHAPLFPSQAPGLL--PPQPS-----
----------------------------------YPFAPQSGV------LGQPPPSLH--
------------P-------QLYPGPSQEPLAPHSGAL-----PFPSPGPPQ---PPHPN
LAYV-PAPS--PRPLG----PQAAPLSI-------------------RGPPPAGQPSPSP
HLV-PSPAPSPGP----GPGPSRPPAAEP-----------PPCLR--RGTA-AADLLSSS
PESQHGGPQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPEKLRRLQQELEAFRG
QL----------GDAAALDATWRELQDAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPCKPVASTSTS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPSGGLDSSAASLPGP
AEP---------PGLPPASLPE-PPPIP----------------------------SSSP
PPLSSPLPETPQPEKEQ----P-VPE---------APNLGPPSSSLELLASLTPEAFSLD
GSLRGKQRISKQNFLQAHNGQGLR-AARPSDDPLSLLDPLWTLNKTC
ENSAPLP00000013471 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------
PF03097 // ENSGT00780000121909_0_Domain_4 (318, 750)
QFVLKNYGENPENYNEELRKLEVLRQNAVNVPRDFEGCSTLRK
YFGQLHYLQSRIPMGAEQEAAVPIAWTEIFSGKT----VTHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFTYLRDHFPHSYSVDMSHQILNLNINLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENSET--VLGKIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVI------
--------------Y-----FQSALDK----------LNEAIKLAKGQPETVQEALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQSVKGTAGAPLVKALPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLRDVMAKIEAKNEVLDQFMDSMQLDPESVDNLEMY
SHIPPVLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKEIRDLLEEDEAQERKLQ
ELLGKSPAP------PGSPPPP-SPGLAEVSKECSKYLEVHEKASFTNTELHKAMNLHIG
NLRLLSGPLEQVRAALPSPSLTEDDKQVVLQNLKRILVKVQEMRDQRLSLEQQLREMIQK
DDITTSLVTADRSEMKKLFEEQLKKYDQIKVYLEQNLAAQ-ENILKALTDANVKYAAVRK
A-LAEVEHKWNTTVQTLVASYEAYEDLMKKSQEGKDFYTDLEGKAAKLLEKARAACQAAE
ANPPSASR----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------SWRS-------------------------------------------
------------------------------------------------------------
--------------------R--------C-P----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------F--R--------------------------------------------
-------------GG---DLGLRAP-----------------------------------
--------L-WGVWDTXLQPTKADAKEGQKPKAVQLIEKDPYEKPEGVLRLLAELERFRG
LLEGLERPAPTGGGGTQLDAVWKELQDAQERDARQLSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2251)
YSMKNRHQDIMPYDRNR
VVLRSGKDDYINASRVEDLSPYCPTVIATQAPLLGTAADFWLMIYEQKVSVVVMLVSEQE
LEK-------------------------QKVLRYFPAERGQPVVQGPVTLVLTGLKATPT
HVERMITLQYRDQSLKRTVIHLQFTSW-PELYENGAGGGRLLRFIQEVHGHYLHQRPLHT
PIVVH---------C----SSGVGRTGAFCLLYAAMQEVEAGNGIPDLPQLVKRLRQQRK
H--------------------------MLQEKV---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------
ENSMPUP00000012037 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------
PF03097 // ENSGT00780000121909_0_Domain_4 (343, 746)
QNAVRVPRDFEGCSVLRK
YLGQLHCLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLCEHFPQAYSVDMSRQILSLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLQARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLWEMMAKIEDQNEVLDQFMDSMQLDPETVDNLDAY
NHIPPQLMEKCAALSVRPDTVRNLVQSMQALSGVFTDVEASLKDIRELLEEDELLEQKLQ
EALGQAGAS------PA----GSKAELAEVRRDWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMQDQRVSLEQQLRELIQK
DDITASLVTADHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRQ
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQARE
AX----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------TPPLH--
------------T-------PLYPGPSQDPLPPHSGAL-----PFPTPGPPQ---SPHPT
LAYG-PAPS--PRPLG----PQAAPLSI-------------------RGPSPAGQPTPNP
HLV-PSPAPSPGP----GRVPPRSPAAEP-----------PPSAR--RGTA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDTAEGRGPQALRLIERDPYEHPERLQQLQRELEAFRG
QL----------GDAAALDAMWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLHLGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEKFL----------------------QQKVARYFPTERGQPMVHGALSLALSSVRATET
HVERVLSLQFRDQSLKRSLLHLHFPTW-PELGLRD-SPGNLLRFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPRLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRPVEQVLQRHGVPPPGRPSAGTSVS--------------
------------QKNHLPQDSQDLVLGGDMPISSIQATIAKLSIRPPGALDSPAASIPGP
VEP---------PGLPPASLPE-STQLP----------------------------PSSP
PPLSSPQPEAPQPEEEQ----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
R----KQRMSKQNFLQAHNGQGLR-AARATDDPLSLLDPLWTLN---
ENSMEUP00000000922 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 750)
-MIWLD------------------
---LKEAGDFNFQPAVRKXXXXXXXXXXXXXXXXXXXXXXXXXNAIRVPRDFEGCSILRK
YLGQLHYLQSRIPMGLENEAAVPITWTEIFSGKS----VTHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFTYLQEHFPHSYSVDMSHQILNLNINLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVVYYKEA
CRALENPETASLLGKVQKDWKKLVQMKTCYFAAVAHLHMGKQAEEQQKFGERVV------
--------------Y-----FQSALDK----------LNEAIKLAKGQPETVQDALRFTM
D-----VIGGKFNSAKKDNDFIYHEAVPVLDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIDAKNEVLDQFMDSLQLDPETVDNLDVY
NHIPPVLMEKCAALSVRPDTVKNLVQSMQVLSGVYTDVEASLKEIKGLLEEDELLEQKVQ
EVSGQPGAV------PA-------GGLAEVSREWAKYMEVHEKASFTNSELHRAMNLHIS
NLRLLSGPLDQVRAALPTPALTPDDKA-VLQNLKRILAKVQEMRDQRLSLEHQLRELIQK
DDITTSLVTTDRSEMKKLFEQQLKKYDQLRVYLDQNLTAQ-ENVLKALTEANVQYAAVRR
V-LTELEHKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVTALLERAKAACQARE
AAFQQLLSREL--------------KKKPPPRPTAPKPLLPRKEEGEA-IEP--------
-------GDLPEELRSLPPDMLAPRL------------PDAFLGA---------------
------------GAVIPFPPGHFT---VPGSHYFP----GPFPPVTYSGPPPLLQPSAPQ
PT-G---------------------LPLAGMSPGPRLYPAP---TYTPDPSLIPGSSPQR
RVVSSHYALGP----------------------------------A--PGGLPTAPPPRF
I---SPELTPGIRPATTTVDSIQAPISSYTAPRPGPSPSPAP-------SRPCYSASQQ-
---------------------GLPAVPYPY-PVGVCQPFLPP-P--NF--LPP-------
--------------------------ASRGELQ--------------PR-----------
-------------PQPYASQVPFVPQP-RPP-PIQHPQVFPPQTGSLL---PL-------
--------------------------------PPFPFVTQPAV------LGQLPPP----
-----------------LGTHLYPLPSQDPLPPHSGAL-----PFPTPAPP--Q-PPHTP
LAYC-PAPA--SRPQVPQA-----------------------PSLPSRGPPPSSQPSPSS
HPV-PSPAPSPGPGP----TTPHPSQAE------------PPPFQ--RCNSSTADLLSSS
PESQHGGSQPPGGGHPLLQPTKADATEGQRPQALRLIECDPYEQPQRLQQLQEELEAFRG
LLS---------GGAGALDGVWRELQEAQERDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YSLKNRHQDIMPYDSNR
VVLRSGKDDYINASRVEGLSSYCPPLIATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVAKYFPTERGQPLVQGPLSLVLSSVRTTDT
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXX---------X----XSGVGRTGAFALLYAAVQEVEAGNGIPALTQLVRQMRQQRK
HMLQE----KLHLRFCHEAVLRHVEQVLQRHGVAPPSACRPLANSS--------------
----------VAQKAYLPQDPQDLVLGADMPISSIQATIAKLSIRPQVGGQEPPP-VALP
SPAEPLS--PTTPNLQ------------------------------------ELTRPPSP
SPPSSPKPEVPEPKEES-----QVPA---------IPSPGPPTSSLELLASLTPEAFSLD
SSLRGKQRMNKQSFLQAHNGQGLR-GAGPSDDPLSLLDPLWTLNKT-
ENSEEUP00000008564 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------
PF03097 // ENSGT00780000121909_0_Domain_4 (319, 658)
FVLKNYGENPEAYNEELKKLELLRQXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVTEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIHYFSAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXX-X-XX--X-XXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLSGVFTDVEASLKDIRDLLEEDELLEQKLQ
EAVGQGGTI------PL----ASKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRATLPTPALSPEDKA-VLQNLKRILAKVQEMRDQRLSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWKSTLQTLVASSEAPTVLMKKSQEGKXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX------XXXXXXXX-XXX--------
-------XXXXXXXXXXXXXXXXXXX-------------XXXXXX---------------
------------XXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXX----
-XXX--------------X---------XXXXXXXXXXXXX---XXXXXXXXX---XXXX
XXXXXXXXXXXXXXX--------------------------------XXXXXXXXXXXXX
X---XXXXXXXVRPATTTVDSVQAPISSHMAPQPSPTPVA---------HQPCFP-----
-------------------------APYGY-PLGTSA-PL---A--VQQHFSP-------
-------------------GVPAGFPTPRIG-----------------------------
-------------PPPQPPRAAFGPQP------QPHPHLFPPQPPGLM--PPQSP-----
----------------------------------YPFTPQPAV------LRQPTPPVH--
-------------------PQLYPGPSQDPLPPHSGAL-----PFPSVGPPQ---PPHPA
LAYG-PAPS--PRPLG----PQATPLAI-------------------RGPTPTGQPAPSP
HPVPPSPAPSPGP----GPVPPRLPAAEL-----------PACPR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDATEGRRPQALRLIERDPYEHPERLQRLQQELEAFRG
RL----------GDAGALDTAWRELQEAQEQDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2337)
YSLKNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVAVIVMLVSEAE
MEKQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------X-------XXXXX
XXXXXXXXXXXX--X---XXXXXXXXX-XXXXXX------XXXXXXXXX-X-XXXXXXXX
XXXXXXX-------XX-X--XXXXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXEAVVRHVEQVLQRHGVPPPCKPSAGAGAD--------------
----------TSQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGALDSQAASLAGP
TEP---------PGLPPANLPESTQ---L-------------------------PPSSPP
PPLPSPLPEAPQPEEEQ----L-VPE---------APNLAPPSSSLELLASLTPEAFSLD
SSLRGKPRMSKQNFLQAHNGQGLR-AAQPADDPLSLLDPLWTLNKT-
ENSCLAP00000023846 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFNFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACTLYNLGALHS
--MLGAVDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPATASLLGRVQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREVMAKIEDKNEVLDQFMDSMQLDPETVDNLDTY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRTLLEEDELQEQKLQ
EATGQTGAG------LA----TAKAELAEVRKEWTKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTDANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSACQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK------PPPRPTAPKPLLPRREESEA-AET--------
-------GDLPEELRSLPPDMVAGPR-----------LPDAFLGA---------------
------------TTPLHFTPGPFANPAVPGPHY----VSGTLPPGTYSGASQLLQARA--
-SGP--------------P--------AMPMAPSPVLYPAP---AYTPELGLVPRSSPQH
SAGSSPYSAVGAPPA---------------------------------IAGLPSAPPPQF
S---------AVRPATTTVDSVQAPISSHLALRPNPSAAP----------QPCFPSQPPP
------------------------PMPYAY-TVGTKQ-PLAAPP--AQHHFSP-------
-------------------GVPTGFLATQGPS----------------------------
-----------IAPQPHPSRAAFGPLPPQQPLPFQQPHLFPPPPPAPGILPSQPP-----
----------------------------------YPFPPRSGVL------AQSPAAL---
------------------HTQLYPGPSPEALQPQAGAL-----PFASPGPPQ---PPHPP
LAYG-PAPS--PSPLG----TQAAPLPM-------------------RGPPPAGQPSPSP
HLV-PSPAPSPGP----APVPSRPPAAEP-----------PACPR--RGMA-AADLLSSS
PESQHGGAQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLGQLQQELEVFRG
QL----------GDAGTLDAVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2225)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
VEK-------------------------QKVARYFPTERSQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHTHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPALPQLVRRMRQQRK
HMLQEKVRAA------G----SGVE---LGLGRGPPSLFLAS------------------
--------PPLSPQNQPPQDSQDLVLGGDVPISSIQATIAKLSIRPAAGMDSPATMQSGP
AET---------LGLVPASLPEP-----V-------------------------PAPSSP
PPLSSPLPEAPQPEEQQ----P-VPE---------APSVGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQSFLQAHNGQGLR-SARAPDDPLSLLDPLWTLNKT-
ENSRBIP00000019063 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MPAAMEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKFNSAKKDNDFIYHEVVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQTGAV------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTEHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYGDLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEV-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGSYSGPTQLIQPRA--
-PGP--------------T--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---GPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQPQP------
----------------Q-PSRAFGPQPPQQPLPLQHPHLFPTQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQ-----H--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--TRPMG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLYFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSMICP00000012451 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAIPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAS------L----AVSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLCALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
VARQQLLDREL--------KK------KPPPRPTAPKPLLARREEGEV-IET--------
-------GDPPEELRSLPPDLVAGPR-----------PPDTFLGT---------------
------------MTPLHFPPGPFPSSTGPGPHY----LSGPLPPGTYSGPTQMIQPRA--
-PGP--------------P--------TMPMAPGPALYPAP---AYTPELGLVPRSSPQH
GMGSSPYGGAGPPPP---------------------------------VAGLPSAPPPQF
S---GPELAVAVRPATTTVDSVQAPISSHTAPRPNPSPAP---------PQPCFPVPPP-
---------------------QPLPTPYSY-PVGAKQ-ALPAPP--AQHHFPP-------
-------------------GIPTGFPAPRM--G----------------PQPHP------
------------------TQAAFGPQPP----QLQHPHLFSPQPPALL--PPHST-----
----------------------------------YSFAPQPGV------LGQPPPL-H--
------------T-------QLYPGPSQDPLPPHSGAL-----PFASPGPPQ---PPHPT
LAYG-PAPS--PRPLG----PQAAPLSI-------------------RGPPPAGQPTPSP
HLV-PSPAPSPGP----GPVASRAPAAEP-----------PLCLR--RGTA-AADLLSSS
PESQHGGAQPPRGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLQQLQLELEAFRG
QL----------GDAGSLDTIWRELQDAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPAPCKPPAS-V----------------
---------SISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGMDSPAASLPGP
AET---------PGLPPATLPE-STPVP----------------------------SSSP
PPLSSPLPEIPQPEEQQ----P-VPE---------APNLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
MGP_CAROLIEiJ_P0090260 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYTEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
ETLGQAGAG------PG--PSVAKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSICRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK-----APPPRPTAPKPLLSRREEGEA-VEA--------
-------GDTPEELRSLPPDMMVGPR-----------LPDPFLGT---------------
------------TAPLHFSPGPFPSSTGPATHY----LSGPLPPGTYSGPTQLMQPRAA-
----------------------------VPMAPATVLYPAP---AYTSELGLVPRSSPQH
GIVSSPYAGVGPPQP---------------------------------VVGLPSAPPPQL
S---GPELAMAVRPATTTVDSVQAPISSHTAPRPNPTPAL---------PQPCFPVPQPV
PQSVPQPQPLPAPYTYSIGTKQPLPAPYTY-SIGTKQ-HLTGPL--PQHQFPP-------
-------------------GIPTGFPVPRTRPQPQPQPQAQPQPQP------------QA
QPQPQPQPQPQPQPQPQPQRPAFGPQPTQQPLPFQHPHLFPSQAPGILPPPPPPP-----
----------------------------------YHFTSQP-SV-----LGQPPPTLH--
------------T-------QLYPGPSQDPLPPHSGAL-----PFPSPGPPHP----HPT
LAYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQQLQQELEAFRG
QL----------GDAGALDGIWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
VEK-------------------------QKVARYFPTERGQPMVHGALSVALSSIRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLKFCHEALMRHVEQVLQRHGVPPPGKPVASVNIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPGL
VEP---------PGLPPASLP-ESTPVP----------------------------SSSP
PPLSSPLPEAPQPEEEP----S-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSSARP00000007700 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 630)
-MIWLD------------------
---LKEAGDFLFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXX
X--XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXX-XX--X-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX---XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX------XX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-------X-XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX------XXXX-----XXXX---------XXXXXXXX-XXX--------
-------XXXXXXXXXXXXXXX-XX---------------XXXXX---------------
------------XXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXQPRVTP
APGH--------------P--------AMAMAPRPALYSAP---GYTPELGLVPRSSPQH
SVVSGPYGRVGHPQP---------------------------------SAGLPSAPPSQF
S---GPELAMGVRPATTTVDSIQAPISSHTAPQANPIPTPP--------PQPCFPVPP--
---------------------QPLPVPYTY-PLGPKQ-PLPAPA--TQHF-SP-------
-------------------GIPTGFPAPRMGPQ---------------------------
-------------PQPHIPQATFGPQPHQQPLPLQHPHLYPPQAPALT--PTQSP-----
----------------------------------YPFAPQPGV------LGQPPPAVH--
-------------------TQIYPGPSQDPLPPHSGAL-----PFPSPGPPQ---PPHHS
LAYG-PAPS--PRPLG----PQAAPLPI-------------------RGPPPASQPSPSP
HLV-PLPAPSPGP----SQVPPRAPAAEP-----------PSCPR--RGAA-TADLLSSS
PESQHGGTQPPGVGQPLLQPTKVDAACR--RPALRLIERDPYERPE-LQRLQQELEAF-G
QL----------GD----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------
ENSCPOP00000020712 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFNFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALESPDTASLLGRVQKDWRKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAMPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREVMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIGTLLEEDELQEQKLQ
EALGQAGTG------PA----TAKGELAEVRKEWTKYMEVHEKASFTNSELHRAMNLHVA
NLRLLSGPLDQVRAALPTPDLTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLDRAQSAYQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQHEAPLPRSSAPARRAVHGNELKKKPPP-----------RPTSEA-TEA--------
-------GDLPEELRSLPPDIAAGPR-----------LPDTFLGA---------------
------------PTPLHFTPGPFPSSTIPGSHY----APGVLPPAPYSGPPKLLQARV--
-SGP--------------L--------AMPVAPSPVLYP--------------------H
GAVSTPYGAVGAPLA---------------------------------GAGLPSAPPSQF
A---GPELAMAVRPATTTVDSVQAPISSHLALQPNPSPA----------PQPCFPSQPMP
P-------------------PQQLPVPYTY-PVGTKQ-PLAAPP--AQLFSS--------
-------------------GVPTGFPPPQGPR----------------------------
-----------ITPQPHPSRAAFGPLPPPQPLPFQHPHLFPPQAPGVI--PSQSP-----
----------------------------------YPFPAPPSGV-----LAQPPAALH--
-------------------TQLYPGPSQEGLPTPAGAL-----PFPNPGTPQ---PPHPP
LAYG-PAPS--PRPMG----TQAAPLPM-------------------RGPPPTGQPSPSA
HLV-PSPAPSPGP----GPVPTRPPATDP-----------PVCPR--RGTA-AADLLSSS
PESQHGGAQPPGGGQPLLQPTKVDAADGRRPQALRLIERDPYEHPERLERLRQELEAFRG
QL----------GDSGALDVVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
IEK-------------------------QKVARYFPTERGQPMVHGALSVALSSVRNTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGSGIPALPQLVRRMRQQRK
HMLQE----KLHLRFCHEGVVRHVEQVLQRHGGPPTLQGPGWC-----------------
-----------QCHQPPPQDSQDLVLGGDVPISSIQATIAKLSIRPTAGMDSPAAMQSGP
TET---------PGLAPVSLSEPAP------------------------------APASP
PPLSSPLPAAPQPEEQP----PLMPE---------APNVGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQSFLQAHNGQGLR-AARAPDDPLSLLDPLWTLNKT-
ENSCGRP00000016169 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQTFSVDMSRHILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPETVDNLEAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEDDELQEQKLQ
ETLGQALAA------PG--SSAAKAELVEVKREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQSLKRILAKVQEMRAQRVSLEQQLRELIQK
DDITASLVTADHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSEVDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERTQSICRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
ATRQQLLDREL--------KKK-----APPPRPTAPKPLLSRREESEA-VEP--------
-------GDPPEELRSLPPDMVVGSR-----------LPDAFLGT---------------
------------TAPLHFSPSPFPSSTGPATHY----LSGPLPPGTYSGPSQPMQPRAP-
----------------------------VPMAPGTVLYPAP---TYTSELGLVPRSSPQR
GIVSSPYVGVGPPPP--------------------------------TVVGLPSAPPPQF
S---GPELAMAVRPATTTVDSVQAPISSHTAPRPNPTPAI---------PQPCFPVPQPV
PQP------------------QPLPTPYTF-SVGTKQ-HLPGPP--PQHHFPP-------
-------------------GIPTGFPAPRIGPQ---------------------------
-----------------PPQPAFGPQPPQQPLPFQHPHLFPSQGPGILPPP-PPP-----
----------------------------------YPFTPQP-GV-----LGQPPPALH--
------------S-------QLYAGPPQDPPPQHSGAP-----PFPSPGPPHP--HPHPT
LAYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGPQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYERPERLQQLQQELETFRG
QL----------GDAGALDTVWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSVALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEALVRHVEQVLQRHGVPPPGKPVASMSIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPGL
VEP---------PGLPPASLPPEPTPLP----------------------------SSSP
PPLSSPLPEAPQPEEEP----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAPPTDDPLSLLDPLWTLNKT-
ENSCGRP00001015493 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MCEEDCACAKKK
KKKRLHGRGLHLP-AGRGGVRQLRVTSGFR--------------RGGAGLRAPLRPQLEL
GGERPG--------------GRQALSAMEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQTFSVDMSRHILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPETVDNLEAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEDDELQEQKLQ
ETLGQALAA------PG--SSAAKAELVEVKREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQSLKRILAKVQEMRAQRVSLEQQLRELIQK
DDITASLVTADHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSEVDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERTQSICRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
ATRQQLLDREL--------KKK-----APPPRPTAPKPLLSRREESEA-VEP--------
-------GDPPEELRSLPPDMVVGSR-----------LPDAFLGT---------------
------------TAPLHFSPSPFPSSTGPATHY----LSGPLPPGTYSGPSQPMQPRAP-
----------------------------VPMAPGTVLYPAP---TYTSELGLVPRSSPQR
GIVSSPYVGVGPPPP--------------------------------TVVGLPSAPPPQF
S---GPELAMAVRPATTTVDSVQAPISSHTAPRPNPTPAI---------PQPCFPVPQPV
PQP------------------QPLPTPYTF-SVGTKQ-HLPGPP--PQHHFPP-------
-------------------GIPTGFPAPRIGPQ---------------------------
-----------------PPQPAFGPQPPQQPLPFQHPHLFPSQGPGILPPP-PPP-----
----------------------------------YPFTPQP-GV-----LGQPPPALH--
------------S-------QLYAGPPQDPPPQHSGAP-----PFPSPGPPHP--HPHPT
LAYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGPQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYERPERLQQLQQELETFRG
QL----------GDAGALDTVWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSVALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEALVRHVEQVLQRHGVPPPGKPVASMSIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPGL
VEP---------PGLPPASLPPEPTPLP----------------------------SSSP
PPLSSPLPEAPQPEEEP----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAPPTDDPLSLLDPLWTLNKT-
ENSHGLP00000016353 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPESYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKT----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRVQKDWKKLVQMKMYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVAALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREVMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRTLLEEDELQEQKVQ
EAMGQAGAG------PA----IAKAELVEVRKEWTKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPVLSPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTADHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSGLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSACQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK------PPPRPTAPKPLLPRREEGEA-VET--------
-------GDPPEELRSLPPDMVAGPR-----------LPDAFLGA---------------
------------ATPLPFTPGPLPSSTGPGPHY----VSGPLPAGTHSGPTQLLQARA--
-PGP--------------L--------AMPLVPAPILYPGP---GYTPELGLVPRSSPQH
GTVSSPYGA---------------------------------------VAGLPSAPPPQC
P---GPALAMAVGPATTTVDSIQAPIPSHMALRPKPSPAP----------QPCFPPQPAP
SQQ-------------PLPLPVPMPVPYTY-PVGTKQ-PLTAPP--AQHHFSP-------
-------------------GVPTGFPPPQGPR----------------------------
-----------IGPQPHPSRAAFGPLPPQQPLPFQHPHLFPPQAPGIL--PPQPP-----
----------------------------------YAFPPQPAV------LGQPPAVLH--
-------------------TQLYAGLSQDTLPASSGAL-----PFPSPGPPQPP-PPHPP
LAYG-PTPS--PRPLG----APAAPLPM-------------------HGPPPAGQPSPSP
HLV-PSPAPSPGP----GPVPPRPPTAEP-----------PACPR--RGPA-AADLLSSS
PESQHGGAQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRCLQQELEAFRG
LL----------GDTGALDAVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRATET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHTHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPLPCKALAGSGPN--------------
------------LKSQLPQDSQDLVLGGDVPISSIQATIAKLSIRPAGGMDSPAAMQPGP
TDT---------PGLPPASLPEP-----M-------------------------PAPCSP
PPLSLPLPDTPQPEEQP----P-VPE---------APSAGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQSFLQAHNGQGLH-AARAPDDPLSLLDPLWTLNKT-
ENSFALP00000002180 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------VP
PF03097 // ENSGT00780000121909_0_Domain_4 (350, 748)
RDFEGCSTLRK
YLGQLHFLQSRIPMGHAQEAAVPVTWTEIFSGKA----VTHEDIKYEQACVLYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFTYLRDHFPHSYSVDMSHQILSLNINLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENSETASLLGKIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVI------
--------------Y-----FQSALDK----------LNEAIKLAKGQPETVQEALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQSVK---GAPLVKALPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLRDVMAKIEAKNEVLDQFMDSMQLDPETVDNLDMY
NHIPPVLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKEIRALLEEDEAQEQKLQ
ELLGRVPPA------PGSP-----PGLAEVSKECSKYLELHEKASFTNTELHRAMNLHLG
NLRLLGGPLEQVRAALPSPSLSEDDKQ-VLQNLKRILAKVQEMRDQRVSLEQQLREMIQK
DDITSSLVTADRSEMKVGPGTALCPARDRPVPSQGPPCAQPRRTVTHCTPGCHLYPALRP
TEPSVPCARWNTTVQTLVASYEAYEDLMKKCQEGKDFYTDLEGKVAKLLERARAACQASE
AQRQQLLERWV-------------GPGQRDPGW-----ELWAWSGGIG------------
--------GSP------------------QPHTEPPAPPSPGGGGGGGGGGGGGGG----
----------------------GGGGGGGGGGG----GGGGGGGGGGGGGG---------
---G----------GGGGGG-GGGGGGGG-------------------G-----------
GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
G---GGGGGGGGGGGG-------G-----------G--------------GGG------G
-------------------GGGGGGGGGGG-GGGGGGG--------------------GG
GGGGG-GG----------------------------------------------------
----------------------------------------------------GG------
--G-------------------GGGGGGGGGGG---------------GGGGG---GGGG
GGG--G------------------------GGGGGGG--------------------GG-
---G-GGGG--GGGGGGGGGGGGGG-----GGGGGGGGGGGGGGGGGGGGGGG-------
-------GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG--GGGGGGGGGGGGG
GGGGGGGGG-GGGGGGGGGGGGGGGGGGGGGGG-----------------------GGGG
GGGGGGGGGAAPGGGSELDALWKELQEAQERDARQRSIAIARCYS
PF00102 // ENSGT00780000121909_0_Domain_8 (1966, 2241)
MKNRHQDIMPYDRNR
VVLRSGKDDYINASRVEDLSPYCPALIATQAPLLGTAADFWLMIYEQKVSVVVMLVSEQE
LDK-------------------------QKVLRYFPSERGQPVAQGPLTVVLTSLRVTPT
HVERMLTLQYRDQSLKRTVAHLQFTSW-PELGLPD-SKGSLLRFIQEVHGHYLHQRPLHT
PVVVH---------C----SSGVGRTGAFCLLYAAVQEVEAGNGIPELAQLVRRMRQQRK
HMLQE----KLHLKFCFEAVLLHAEQVLLRHGVGGPSLAKPPSSAS--------------
------------PKLYFQQDPQDLVLGGDVPISSIQATIAKLSIKPGGGGAGPRAGLGAG
TATAP-------AGLVP----LCPPGPSAAPAG---------------------------
----EEPPLAPQRDEEQEEEEAEEGAIAAGGSRAGQLCRGTEGQHCRGWASLTPEAFSLD
ASLKGKQRMNKQNFLQAQPGEGLR-GPRPSDDPLSMLDPLWTLNKA-
ENSSSCP00000042659 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--M
PF03097 // ENSGT00780000121909_0_Domain_4 (424, 746)
LGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSLQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRALLEEDELLEQKLQ
EAVGQAGAS------TA----VSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREEGEV-VEP--------
-------GDLPEELRSLPPD--------------------TFLGA---------------
------------AARLHFPPGPFPSSAGPGPHY----LSGVLPPGTYSGPTQVLQPRAPP
APGH--------------P--------AVAMAPGPPLYAAP---AFTPELGLVPRSSPQH
GVVSSPYGGVGPPPP---------------------------------VAGLPSAPPPQF
S---GPELAMGVRPATTTVDSVQAPISSHTAPRPTPTPAP---------PQPCFPGHPP-
---------------------QPLPMPYAY-PVGAKQ-PLTAPP--AQHHFSP-------
-------------------GIPTGFSVPRIG-----------------------------
-------------PQPHPTRTVFGPQPPQQPLPLQHPHLFPSQAPGLV--PPQPP-----
----------------------------------YPFAPQPGV------LGQPPPTLH--
------------T-------QLYSGPSQDPLPPHSGAL-----PFPSPGPPQ---PPHPT
LAYG-PAPS--PRPMG----PQAAPLSI-------------------RGPPPAGQPTSTP
NLV-PSPAPSPGP----GPVPPRPPASEP-----------PSCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLQQLQQELEAFRG
QL----------GDTGSLDAVWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEKVRQGGRVGAQQGPWKHALTALFVPQQKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLKFCHEAVVRHVEQVLQRHGVLPPCRPSASISVSQKVMEGALESAGDS
SCLVDPSLPILSSQNHLPPDSQDLVLGGDVPISSIQATIAKLSIRPSGGLDSPAASLPGP
VEA---------AGLPPTSLPE-STQLP----------------------------SSSP
PPLSSPLPEAPQPEEEP----P-VPE---------VPTLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSECAP00000014531 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MEAV-------PRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 748)
-MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLDQKLQ
EAVGQAGAS------LA----VSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEIKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQARE
AARQQLLDREL---------KKK-----PPPRPTAPKPFLPRREEGEA-VET--------
-------ADLPEELRSLPPDMVVGPR-----------PPDTFLGT---------------
------------AAPLHFPPSPFPASAGPGPHY----LSGPLPAGTYSGPTQMLQPRAPQ
APGH--------------P--------AMAMVPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYGGVGPPPA---------------------------------VAGMPSAPPPQF
S---GPELTMGVRPATTTVDSVQAPISSHTAPRPNPSPVP---------PQPCFPVPPQQ
--------------------P--LPTPYTY-PLGA-KQPLPAPT--AQHHFS--------
-------P-----------GIPTGFPAPR--VG----------------PQPQP------
----------------QPTRAAFGPPPPQQPLALQHPHLFPPQAPALV--ASQRP-----
----------------------------------YPFAPQPGV------LGQPPPALH--
------------T-------QVYPGPSQDPLPPHSGAL-----PFPSPGPPQ---SPHPT
LAYG-PAPA--SRPLG----PQAAPLSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PSCLR--RGTA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLQQLQQELEAFRG
QL----------GDAAALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFSTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGMPPPCKPSAGTSIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSPAASLPGP
VEP---------PGPLPASLPE-STQLP----------------------------SSSP
PPLSSPLPEAPQPEEEQ----P-APE---------VPSVGPPSSSLELLASLTPEAFSLD
SSLQRKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSPPYP00000015571 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 748)
-MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAI------S----APSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPVLTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQARE
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-VEA--------
-------GDPPEELRSFPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------P--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---GPELAMAVRPATTTVDSIQAPIPSHTTPRPNPTPAP---------PQPCFPVPPP-
---------------------QPLPTPYTY-PVGAKQ-PIPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PRPQP----H-
-------------PQPH-PSRAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPPPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LGYG-PAPS--TRPMG----PQAAPLTI-------------------RGPSSAGQSTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGTA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLLPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATRPSDDPLSLLDPLWTLNKT-
ENSCHOP00000001366 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 750)
-MIWLD------------------
---LKEAGDFHFQPDVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAISVTWTEIFSGKS----VAHEDIKYEQACILYNLXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXX--
-------------------------XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXX----X--XXXXXXXXXXXXXXXXXXXXXXXXX---------------XXXXXXXXX
XXXXXXXXXXXXXXXXXVAYFQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHESVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX----------XXX---------XXXXXXX---XXXXXXXX----------
-----XXXX---------------XXX--XXXXXXXXXXXXX---XXXX-XXX-XXXXX-
---------------------XXXXXX-XXXXXXXXXX-------------------X-X
XXXXXXXXXXX-----XXX-----XXX-XXXXXXXXXXXX-----------XXXXXXXXX
X-------XXXXX----X--XXXXXXXXX-----XXXXXXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXX-------------------------------XXXXXX-XXX--------
--------X-------------------------------XXXXX---------------
----------------------XX---XXXXXX----X-XXX------------------
-XXX--------------X--------XXXX---------X-------X----------X
XXXXXXXXXXX---X---------------------------------XXXX-----XXX
X---XX-----------------X-----------X--------------XXXXXX--XX
--------------------XXXXXXXXXX-XXXXXX-XXXX-X--XXXXXXX-------
-------------------------------X----------------------------
------------------X---------XX--------------XXX-----XX------
----------------------------------------------------XXXXXXXX
XXXXXXXXXXXXXXPPPLHTQLYPGPSQDPLPPHSGAL-----PFPSPGPPQ---PPHPT
LAYGS-TPS--PRPLS----SQAAPLSI-------------------RGTPPASQPAPTP
HLV-PSPAPSPGP----GSVPPRPPTAEP-----------PPCLR--RGF-AAADLLSSS
PESQHGGSQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPDRLRQLQQELETFRG
QL----------GDAGTLDTVWRELQDAQEHDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YSLKNRHQDVMPYDSNR
VVLRSRKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVVRYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGHLLCFIQEVHAHYLHQRPLHT
PIVVH---------C----SSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRHMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPCKPLASTSNS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIARLSIRPPGGMDIPPASLPGP
AEL---------PTLPPASLMEP-PQL----------------------------PASSP
PPPPSPLPEAPQPEEEL-----LVPE---------TPSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSGGOP00000003045 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDVY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIKDLLEEDELLEQKFQ
EAVGQAGAI------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALSPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-VEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------P--------AMPVAPGPAVYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---GPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAP---------PPPCFPVPPP-
---------------------QPLPTPYTY-PAGAKQ-PIPA-----QHHFSS-------
-------------------GIPAGFPAPRI--G----------------PQP--------
--------------QPH-PSQAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPPP----
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--TRPMG----PQAAPLTI-------------------RGPSSAGQSTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHAERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKHNFLQAHNGQGLR-ATRPSDDPLSLLDPLWTLNKT-
ENSCAPP00000017381 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MCVPAHSLLSL
PF03097 // ENSGT00780000121909_0_Domain_4 (318, 746)
QFVLKNYGENPEAYNEELKKLELLRQNAIRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALESPDTASLLGRVQKDWRKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAMPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREVMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIGTLLEEDELQEQKLQ
EALGQAGTG------PA----TAKGELAEVRKEWTKYMEVHEKASFTNSELHRAMNLHVA
NLRLLSGPLDQVRAALPTPDLTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLDRAQSAYQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQHEAPLPRSSAPARRAVHGNELKKKPPP-----------RPTSEA-TEA--------
-------GDLPEELRSLPPDIAAGPR-----------LPDTFLGA---------------
------------PTPLHFTPGPFPSSTIPGSHY----APGVLPPAPYSGPPKLLQARV--
-SGP--------------L--------AMPVAPSPVLYP--------------------H
GAVSTPYGAVGVPLA---------------------------------GAGLPSAPPSQF
A---GPELAMAVRPATTTVDSVQAPISSHLALQPNPSPA----------PQPCFPSQPMP
P-------------------PQQLPVPYTY-PVGTKQ-PLAAPP--AQLFSS--------
-------------------GVPTGFPPPQGPR----------------------------
-----------ITPQPHPSRAAFGPLPPPQPLPFQHPHLFPPQAPGVI--PSQSP-----
----------------------------------YPFPAPPSGV-----LAQPPAALH--
-------------------TQLYPGPSQEGLPTPAGAL-----PFPNPGTPQ---PPHPP
LAYG-PAPS--PRPMG----TQAAPLPM-------------------RGPPPTGQPSPSA
HLV-PSPAPSPGP----GPVPTRPPATDP-----------PVCPR--RGTA-AADLLSSS
PESQHGGAQPPGGGQPLLQPTKVDAADGRRPQALRLIERDPYEHPERLERLRQELEAFRG
QL----------GDSGALDVVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
IEK-------------------------QKVARYFPTERGQPMVHGALSVALSSVRNTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGSGIPALPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPCKALAG------------------
-----------ANSQPPPQDSQDLVLGGDVPISSIQATIAKLSIRPTAGMDSPAAMQSGP
TET---------PGLAPVSLTEPAP------------------------------APASP
PPLSSPLPAAPQPEEQP----PLMPE---------APNVGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQSFLQAHNGQGLR-AARAPDDPLSLLDPLWTLNKT-
ENSTBEP00000011513 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 813)
-MIWLD------------------
---LKEAGDFHFQPAVKKXXXXXXXXXXXXXXXXXXXXXXXXXNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKIFLVARISSQXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----X
X------------XXXXX--XXXXXXX----------XXXXXXXXXXXXXXXXXXXXXXX
XXXX--XXXXXXXXXXXXXXXXXXXXX-XXXX-----------XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXEEKAKALREMMPKIEDKNEVLNQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKLQ
EAVGQAGAT------PP----VSKAELAEVRREWAKYKEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTEHSEMKKLFEEQLKKYDRLRVYLEQNLAAQ-DNVLRALTEANLQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQATCQARE
AARQQLLDREL--------------KKKPPPRPTAPKPLLARKEESEA-VET--------
-------GDPPEELRSLPPDMVAVPR-----------PPDTFLGT---------------
------------AAPLHFTPGPG--PTGLGPHY----LSGPLPPGACPGPAQLLQPRV--
-PGA--------------P--------TVPMTAGPVLYPAP---AYTPELALVPRSSPQH
GVVSSPYGGGRATLP---------------------------------VTGLPSAPPPQF
S----PELALAVRPATTTVDSVQAPISSHGAPRP--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------
ENSGALP00000051392 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------MEAVPRMPMIWLDLKEAG--------EFAFNAAV
PF03097 // ENSGT00780000121909_0_Domain_4 (342, 746)
KKSAVNVPRDFEGCSTLRK
YFGQLHYLQSRIPMGAEQEAAVPITWTEIFSGKT----VTHEDIKYEQACILYNLGALHS
--MLGAMDKRVSE----------ECAAGAFTYLRDHFPHSYSVDMSHQILNLNINLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENSETASLLGKIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVI------
--------------Y-----FQSALDK----------LNEAIKLAKGQPETVQEALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQSVK---GAPLVKALPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LRDVMAKIEAKNEVLDQFMDSMQLDPETVDNLDMY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1078)
IPPILMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKEIRDLLEEDEAQERKLQ
ELLGKGSVP------QGSPPPPSSTGLAEVSKECSKYMEVHEKASFTNTELHKAMNLHIG
NLRLLSGPLEQVRAALPSPTLSEDDKQ-VLQNLKRILGKVQEMRDQRMSLEQQLREMIQK
DDITTSLVTTDRSEMKKLFEEQLKKYDQIKVYLEQNLAAQ-ENILKALTDANVKYAAVRK
A-LAEVEHKWNTTVQTLVASYEAYEDLMKKSQEGKDFYTDLEGKAAKLLEKARAACQAAE
ANRQQILEKEM-------------KKHPPPRPTA--------------------------
------------------------------------------------------------
------------------------------PK----------------------------
------------------------------------------------------------
---PALQK---KPLELE-------------------------------------------
------------------------------------------------------------
--------------------A--------E-GP---------------------------
-EVGD-------------------------------------------------------
------------------------------------------------------------
---------------------------------------LPPLAS----LGLAD------
------------------------------------------------------------
----LPE-----------------------------------------------------
--------------ELRRLRAPRPSDDPLS---------------------MLDPLWTLN
KS----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------
ENSHGLP00100024238 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--MIWLD------------------
---------------
PF03097 // ENSGT00780000121909_0_Domain_4 (316, 746)
LKEFVLKNYGENPESYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKT----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRVQKDWKKLVQMKMYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVAALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREVMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRTLLEEDELQEQKVQ
--------------------------------EWTKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPVLSPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTADHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSGLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSACQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AAPALWAG--------------------------------FREEEGEA-VET--------
-------GDPPEELRSLPPDMVAGPR-----------LPDAFLGA---------------
------------ATPLPFTPGPLPSSTGPGPHY----VSGPLPAGTHSGPTQLLPARD--
-PGP--------------L--------AMPLVPAPILYPGP---GYTPELGLVPRSSPQH
GTVSSPYGG---------------------------------------VAGLPSSPPPQC
P---GPALAMAVGPATTTVDSIQAPIPSHMALRPKPSPAP----------QPCFPPQPAP
SQQ-------------PLPLPVPMPVPYTY-PVGTKQ-PLTAPP--AQHHFSP-------
-------------------GVPTGFPPPQGPRI---------------------------
------------GPQPHPXXXXXXXXXXXXXXXXXXX---------------XXX-----
----------------------------------XXX--XXXXX-----X----------
---------------------XXXXXXXXXXXXXXXXXXXXXXXXPSPGPPQPP-PPHPP
LAYG-PTPS--PRPLG----APAAPLPM-------------------HGPPPAGQPSPSP
HLV-PSPAPSPGP----GPVPPRPPTAEP-----------PACPR--RGPA-AADLLSSS
PESQHGGAQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRCLQQELEAFRG
LL----------GDTGALDAVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRATET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHTHYLHQRPLHT
PIVVH---------C----SSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPLPCKA---------------------
-------------LSQLPQDSQDLVLGGDVPISSIQATIAKLSIRPAGGMDSPAAMQPGP
TDT---------PGLPPASLPEP-----M-------------------------PAPCSP
PPLSLPLPDTPQPEEQP----P-VPE---------APSAGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQSFLQAHNGQGLH-AARAPDDPLSLLDPLWTLNKT-
ENSCHIP00000005775 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWL-------------------
--DLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVSVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFSYLREHFPQAYSVDMSRQILTLNANLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKCGEQVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSLQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDEVLEQKLQ
EAVGPAVAS------TA----VSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPSPALSPEDRA-VLQNLKRILGKVQEMRDQRVSLEQQLRELIQK
DDITAALVTADHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQSLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSACQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
ATRQQLLDREL--------KK------KPPPRPTAPKPLLPRREEGEA-MEA--------
-------GDLPEELRSLPPE--------------------PFLGA---------------
------------ATPLHFPPSPFPSSAGPGPHY----LSGALPPGTYAGPTQMLQPRAPQ
PPGH--------------P--------GVAVAPGPALYTAP---AYAPELGLVPRSSPQH
GMVSSPYGAVGPPPP---------------------------------LAGLPSAPPPHF
S---GHELAMGVRPATTTVDSVQAPISSHAAPRPNPAPAP---------PQACFPGPPP-
---------------------QPLPLPYTY-PMGPKQ-PLTAPP--AQHH----------
-----F-----------PPGVPAGFPAPR-------------------------------
----------------------MAPQPPPQPLPLQHPHVFPPQAPGLM--PAQAP-----
----------------------------------YPFAPQPGV------LGQPSPALH--
------------T-------QLYPGPSQDPLPPHSGAL-----PFPSAGPPQ---PPHRT
LAYG-PAPA--PRPLG----PQAAPLSI-------------------RGPPPAIQPAPTP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PSCLR--RGSA-AADLLSSS
PESQHGGPQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYERPERLQQLRQELEAFRG
QL----------EAAGALDTVWRELQDAQELDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSHLLHFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGSGIPQLPQLVRRMRQQRK
HMLQE----KLHLKFCHEAVVRHVEQVLQRHGMPPPSKPTAGTGIA--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGVDSPAASLPGP
VEP---------PGPPPPSLPE-STQLP----------------------------PSSP
PPLSSPVPEAPQPEEEQ----P-VPE---------APILGPPSSSLELLASLTPEAFSLD
GSLRGKQRMSKQDFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSPEMP00000019951 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 581)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYL------------------TEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPETASLLGRIQKDWKKLVQMKIYYFAAVAHVRQA
ENSGT00780000121909_0_Linker_4_6 (581, 669)
VTGCVPGSSGLRGSLL----
---------------------------------------------CG------SL----V
ICDFSPPA
PF03097 // ENSGT00780000121909_0_Domain_6 (669, 746)
THRYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_6_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
ETLGQAGAA------P--GASAAKAELVEVRREWAKYMEVHEKASFTNSELHRAMNLHIG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERTQSICRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDRWVCAL----------------AGLTSLPPLLSRREEGEA-VET--------
-------GDPPEELRSLPPDMVVGSR-----------LPDPFLGT---------------
------------PAPLHFSPGPYPSPTGPTQL---------------------MQ-----
-QPR--------------A--------AVPMASGTVLYPAP---AYTSE--FVPRSSPQH
GVVSSPFVGVGPPPP---------------------------------VVGLPSAPPPQF
S---GPELAMTVRPATTTVDSVQAPISSHTAPRPNPTPAL---------PQPCFPVPQPV
SQ-----------------------------------PHLTGPP--PQHHFPP-------
-------------------GIPTGFPAPRIGPQ--------------AQPQPH-------
-----------PPPPPPPPQPAFGPQPPQQPLPFQHPHLFPSQAPRILP---PLP-----
----------------------------------YPFTPQPGV------LGQPSPTLH--
-------------------SQLYPGPSQDPLPPHSGAL-----PFPNPGPPH----PHPT
LAYG-PAPS--PRPLG----PPATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQQELETFRG
QL----------GDVGALDAIWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSVALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEALVRHVEQVLQRHGVPPPGKPVASMSIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPGL
VET---------PGLPPASLPEPT-PVP----------------------------SSSP
PPLSSPLPETPQPEEEP----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSOPRP00000004849 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------
PF03097 // ENSGT00780000121909_0_Domain_4 (319, 750)
FVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFER--ALHK
YLGQLHCLDGGEAKGSGQEASVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVKNLVQSMQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX------XX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXDKA-VLQNLKRILAKVQEMREQRLSLEQQLRELIQK
DDITASLVTTEHSEIQKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERARTTCQARE
AARQQLLDREL--------------KKKPPPRPTAPKPLLPRREEGEA-VET--------
-------GDAPEELRSLPPDMVAGAR-----------PPDTFLGA---------------
------------AAPFHFAPSPFPNATGPGPHY----FPGPLPPGTYSGPTQLMQPRT--
-TGP--------------P--------TVPIAPGPALYPAP---AYTAELGCVPQSSPQH
GVVSSPY-----------------------------------------VAGLPSAPPPQF
S---GPELAMGVRPATTTVDSVQAPIPSHTTPRSNPTPAPP--------SQPCFPVPP--
--------------------------PYPY-PVGAQQA----LT--AQHPFPP-------
-------------------GIPTGFPAPRMG-----------------------------
-------------PQPHPSRSAFGPQPAQQPLPLQHPPLFPSQVPRLQ--PPQAP-----
----------------------------------YPFVPQPGV------LGQPPPPLH--
-------------------PQLYPGPAQEPVTPHSRAV-----PFPSPGPPQ---TPHPP
LAYG-PSPS--PRQLG----PQATPLSI-------------------RGPSPAGQPSPAP
HLV-PSPAPSPGP----GPGPSRPPAAEP-----------PPCLR--RGTA-AADLLSSS
PESQHGGPQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPEKLRRLQQELEAFRS
QL----------GDAGTLDATWRELQEAQEQDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YSLKNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLIATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGSSIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPCKPAASTSLN--------------
------------HKNPFPQDSQDLVLGGDVPISSIQATIAKLSIRPSGE--SSAASLPGP
VEP---------PGLPPASLPEPTP-VP----------------------------SSSP
PPLSSPLPETPQPEEEQ----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSFDAP00000013567 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MFQ--QHWRLLDS-SGHWVGMDLKGWVG
NRDFQEEGP--SDWG
PF03097 // ENSGT00780000121909_0_Domain_4 (316, 746)
FRKFVLKNYGENPEAYNEELKKLELLRQNAVRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKT----MTHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRVQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREVMAKIEDKNEVLDQFMDSMQLDPETVDNLDTY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1081)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRTLLEEDELQEQKLQ
EAVGQAGAC------PA----TTKAELAEVRKEWTKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDRA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITTSLVTADHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSGLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERTQSACQARE
ENSGT00780000121909_0_Linker_7_9 (1081, 1967)

TARQQLLDREL--------------KKKPPPRPTAPKPLLPRREEGEA-VET--------
-------GDPPEELRSLPPDMVAGPR-----------LPDAFLGA---------------
------------ATPLHFTPGPLPGSTVPGPHY----VSGSLPAGTYSGPSPLLQARA--
-SGP--------------P--------AMPMAPAPVLYPAP---AYTPELGLVPRSSPQH
GTVSSPYGAVGAPPP---------------------------------VTGLPSAPPPQF
G---GPELRMAVRPATTTVDSVQAPISSHMALRPNPSPAL---------PQPCFPQ----
---------------------QPLPAPYTY-PVGAKQ-PLPAPS--AQHHFSP-------
-------------------GVPTAFPPPQGPR----------------------------
-----------IGPQPHPSRAAFGPLPPQQPLPFQHPHLFPPQAPGIL--PPQPP-----
----------------------------------YPFPPQPGVL------GQPT------
------------------------------------------------------------
------------------------------------------------------------
---------------------------AP-----------SACPR--RGPV-AADLLSSS
PESQHSGAQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLWRLQHELEAFRG
QL----------GDAGALDAVWRELQEAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_9 (1967, 2043)
KNRHQDIMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
ME
ENSGT00780000121909_0_Linker_9_8 (2043, 2126)
KVGGAPE---------------------------------------------------
------------------------A
PF00102 // ENSGT00780000121909_0_Domain_8 (2126, 2241)
EWVVGRGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVGPPSWASARPHCPLSLSSGVGRTGAFALLYAAVQEVEAGNGLPQLPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPAPCKAAAAAGTN--------------
------------QKSQLPPDSQDLVLGGDVPISSIQATIAKLSIRPAGGLDSPAALQPSA
TET---------PGPLPASLPEP-----V-------------------------PAPSSP
PPLASPLPDAPQPEEQQ----A-VLE---------APSTAPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQSFLQAHNGQGLR-AAQALDDPLSLLDPLWTLNKT-
ENSPANP00000003607 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALLCGG
G----PGSFFLFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQTGAT------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------A--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---SPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPCFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQP--------
--------------QPH-PSRAFGPQPPQQPLPLQHPHLFPPHAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPTPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--ARPVG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSLAFP00000013573 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 750)
-MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGLGQEAAVAVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREIMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDERLEQKFQ
EAVGQAGAS------PA----APTAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTAEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEIKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDHKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSTCQARE
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREEGEV-VET--------
-------GDLPEELRSLPPDMVAGPR-----------PSDTFLGT---------------
------------ATPLHFSPSPFPGSAGPGPHY----LSSPLPPGTYLGSTPMLQPRPPH
ALGH--------------A--------AMAVAPGPAHYPNP---AYTPELGLVPRSSPQH
GVVSSPYGGVGPPLP---------------------------------VAALPSAPPPQF
S---GPELAMGVRPATTTVDSVQAPIPSHMAPRPNPAPAP---------AQPCFPVPPP-
---------------------QPLSTPYTY-TVGAKQ-PLTAPP--AQHHFPP-------
-------------------SIPTGFPAPRVG------------------PQPHP------
------------------SRAAFRPQAPQQPLALQHPQLFPPQAPGPL--PPQAT-----
----------------------------------WPFPPQPGV------LGQLPPPLH--
------------A-------QLYPGPTQDLLPPPCGL------LFPSPGTRLIR--PHND
KLR-----------NT----IEARSRGL-------------------RAPPPVSQPAPSP
HLV-PSPAPSPGP----GQGAPRPPAAEL-----------PPCLR--RGST-AADLLSSS
PESQHSGSQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQQELEAFRG
QL----------GDAGALDTVWRELQDAQEHDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YSLKNRHQDVMPYDSNR
VVLRSGKDDYINASRVEELSPYCPPLVATQAPLPGTAADFWLMVHEQKVSIIVMLVSEAE
MEK-------------------------QKVTRYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGLPPPCKPLASTG----------------
----------VTQKNHLPQDSQDLVLGGDVPISS-QATIAKLSIRPPGGLESPAASLPGP
AEH---------PGLPPPSLTE-STQLP----------------------------SSSP
PPPSSPLPEVPQPEEEL----S-VPK---------APSPGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPADDPLSLLDPLWTLNKT-
ENSNLEP00000007674 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 739)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALLCG-
-----GGPGSLFFSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLY
ENSGT00780000121909_0_Linker_4_7 (739, 783)
RWVEGG-----------TEGGGVQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EVVGQVGAI------S----APSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTSEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREDSEA-VEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATALHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------P--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---GPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAP---------PQPCFPVPPP-
---------------------QPLPTPYTY-PAGAKQ-PIPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQPQP------
----------------H-PSRAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPPPLH--
------------T-------QLYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--TRPMG----PQAAPLTI-------------------RGPSSAGQSTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVMRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQPIPGKGW--GTQPSDDPLSLLDPQWTLNKT-
ENSCJAP00000051721 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILSLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKYNSAKKDNDFIYHDAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDEVLEQKFQ
EAVGQAGAI------SAAISAVSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVS
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRILRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLECTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-VEA--------
-------GDPPEELRSLPPDMVAAPR-----------PPDAFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPMPPGTYSGPTQLMQPRA--
-PGP--------------S--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYRGVGPAPP---------------------------------VAGLPSAP-PQF
S---GPELAMGVRPATTTVDSIQAPISSHMAPRPNPTPTP---------PQPCFPVPPP-
---------------------QPLPTPYTY-PVGAKQ-PIPA-----QHHFSP-------
-------------------GIPTGFPAPRI--G----------------PRPQPQPQ---
-----------PQPQPH-PSQAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQPP-----
----------------------------------YTYAPQPGV------LGQPPPPLH--
------------T-------QLYPGPAQDTLPPHSGAL-----PFPSPGPPR---PPHPP
LAYG-PAPS--ARPMG----PQAAPLTI-------------------RGPLPAGQPTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAT-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRKPQALRLIEQDPYEHPERLRQLQQELEAFRG
QL----------GDMGALDTIWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVARHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESLAASLPGP
AEP---------PGLLPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPEEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATRPSDDPLSLLDPLWTLNKT-
ENSP00000265562 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAI------S----ITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALSPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLCALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-VEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGS---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------H--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---GPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAP---------PPPCFPVPPP-
---------------------QPLPTPYTY-PAGAKQ-PIPA-----QHHFSS-------
-------------------GIPAGFPAPRI--G----------------PQPQ----PH-
-------------PQPH-PSQAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPPPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--TRPMG----PQAAPLTI-------------------RGPSSAGQSTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKHNFLQAHNGQGLR-ATRPSDDPLSLLDPLWTLNKT-
ENSSBOP00000000750 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAI------S----TTSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-VEA--------
-------GEPPEELRSLPPDMVAAPR-----------PPDVFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPMPPGTYSGPSQLIQPRA--
-PGP--------------S--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYGGVGPAPP---------------------------------LAGLPSAP-PQF
S---GPELAMGVRPATTTVDSIQAPISSHMAPRPSPTPAP---------PQPCFPVPPP-
---------------------QPLPTPYTY-PVGAKQ-PIPT-----QHHFSP-------
-------------------GIPTGFPAPRI--G----------------PRPQ-------
-------------PQPH-PSQAFGPQPPQQPLPLQHPHLFPPQASGLL--PQQSP-----
----------------------------------YTYAPQPGI------LGQPPPPLH--
------------T-------QLYPGPAQDPLPPHSGAL-----PFTSPGPPR---PPHPP
LAYG-PAPS--TRPMG----PQAAPLTI-------------------RGPLPPGQPTPSP
HLV-PSPAPSPGP----GPVAPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQQLEQELEAFRG
QL----------GDVGALDTIWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVARHVEQVLQRHGVPPPCKPLASASISQKVRKVPWKLLGWP
QPWDSLSSPTLSSQNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESLAASLPGP
AEP---------QGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPEEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATRPSDDPLSLLDPLWTLSKT-
ENSANAP00000024448 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGEQAL------
--------------P-----LS--------------------LTPQGQPDTVQDALLCGG
GPGFLFFQRVLYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAI------S----TASKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPHREESEA-VEA--------
-------GDLPEELRSLPPDMVAAPR-----------PPDAFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPMPPGTYSGPTQLIQPRA--
-PGP--------------S--------AMPVAPGPALYLAP---AYTPELGLVPRSSPEH
GVLSSPYGGVGPAPP---------------------------------VAGLPSAP-PQF
S---GPELAMGVRPATTTVDSIQAPISSHMAPQPNPTPAP---------PQPCFPVPPP-
---------------------QPLPTPYTY-PVGAKQ-PIPA-----QHHFSP-------
-------------------GIPTGFP----------------------------------
-------------PQPH-PSQVFGPQPPQQLLPPQHPHLFPPQASGLL--PPQSP-----
----------------------------------YTYASQPAV------LGQPPPPLH--
------------T-------QLYPGPAQDLLPPHSGAL-----PFPSPGPPR---PPHPP
LAYG-PPPS--TRPMG----PQAAPLTI-------------------RGSLPAGQPTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQQKLEAFRG
QL----------GDMGALDTIWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2224)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMIWAGGLGWLHLRFCYEAVARHVEQVLQRHGVPPPCKPLASTSISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESLAANLPGP
AEP---------PGLP-ASLPE-STPIP----------------------------SSSP
PPLSSPVPEAPQPEEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSCATP00000025642 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQTGAT------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------A--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVNSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---SPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQP--------
--------------QPH-PSRAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPTPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--ARPVG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVVRYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPISSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSMUSP00000039580 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKS----VSHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
ETLGQAGAG------PG--PSVAKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSICRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK-----APPPRPTAPKPLLSRREEGEA-VEA--------
-------GDTPEELRSLPPDMMVGPR-----------LPDPFLGT---------------
------------TAPLHFSPGPFPSSTGPATHY----LSGPLPPGTYSGPTQLMQPRAA-
----------------------------VPMAPATVLYPAP---AYTSELGLVPRSSPQH
GIVSSPYAGVGPPQP---------------------------------VVGLPSAPPPQL
S---GPELAMTVRPATTTVDSVQAPISSHTAPRPNPTPAL---------PQPCFPVPQPV
PQSVPQPQPLPVPYTYSIGTKQPLPAPYTY-SIGTKQ-HLTGPL--PQHQFPP-------
-------------------GIPTGFPVPRTGPQAQAQPQPQPQPQPQPQ------PQPQP
QPQPQSQSQPQPQPQPQPQRPAFGPQPTQQPLPFQHPHLFPSQAPGILPPPPPTP-----
----------------------------------YHFTPQP-GV-----LGQPPPTLH--
------------T-------QLYPGPSQDPLPPHSGAL-----PFPSPGPPHP----HPT
LAYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQQLQQELEAFRG
QL----------GDAGALDAIWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSVALSSIRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLKFCHEALVRHVEQVLQRHGVPPPGKPVASVNIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPGL
VEP---------PGLPPASLP-ESTPVP----------------------------SSSP
PPLSSPLPEAPQPEEEP----S-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
MGP_SPRETEiJ_P0093987 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
ETLGQAGVG------PG--PSVAKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSICRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK-----APPPRPTAPKPLLSRREEGEA-VEA--------
-------GDTPEELRSLPPDMMVGPR-----------LPDPFLGT---------------
------------TAPLHFSPGPFPSSTGPTTHY----LSGPLPPGTYSGPTQLMQPRAA-
----------------------------VPMAPATVLYPAP---AYTSELGLVPRSSPQH
GIVSSPYAGVGPPQP---------------------------------VVGLPSAPPPQL
S---GPELAMTVRPATTTVDSVQAPISSHTAPRPNPTPAL---------PQPCFPVPQPV
PQSVPQPQPLPVPYTYSIGTKQPLPAPYTY-SIGTKQ-HLTGPL--PQHQFPP-------
-------------------GIPTGFPVPRTGPQAQAQPQPQPQPQPQPQ------PQP--
----------QPQPQPQPQRPAFGPQPTQQPLPFQHPHLFPSQAPGILPPPPPPP-----
----------------------------------YHFTPQP-GV-----LGQPPPTLH--
------------T-------QLYPGPSQDPLPPHSGAL-----PFPSPGPPHP----HPT
LAYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQQLQQELEAFRG
QL----------GDAGALDATWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSVALSSIRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLKFCHEALVRHVEQVLQRHGVPPPGKPVASVNIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPGL
VEP---------PGLPPASLP-EPTPVP----------------------------SSSP
PPLSSPLPEAPQPEEEP----S-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSCSAP00000012103 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 748)
-MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQTGAT------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQARE
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------A--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGVPSAPPPQF
S---GPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQP--------
--------------QPH-PSRAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPTPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPS
LAYG-PAPS--TRPVG----PQAAPLTI-------------------RGPLPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASITQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSSHAP00000008711 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------PDDKA-VLQNLKRILGKVQEMRDQRLSLEHQLRELIQK
DDITTSLVTTDRSEMKKLFEEQLKKYDQLRVYLDQNLVAQ-ENILKALTEANVQYAAVRR
V-LAELEHKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVSALLERAKAACQARE
AAFQQLLSREL--------------KKKPPPRPTAPKPLLPRKEEGEA-GEP--------
-------GDLPEELRSLPPDMLAAHLTTFPTGTL---PSEAFLGA---------------
------------GAIMPFPPSHFA---VPGSHYIPSQGSGPFPPGTYSGPPPLLQPSAPQ
PTVG---------------------LPLPGLASGPRLYPAP---GYAPDPGLIPAS-PQH
RLVSSHYALGP----------------------------------PGSTGGLPTAPPPRF
I---SPELAPGIRPATTTVDSVQAPISSYTAPRPGPSPSPAP-------TRPCYSASQQ-
---------------------GVPTVPYPY-PIGVCQPFTPS-S--AQLPFPP-------
--------------------------APRGELQ--------------PR-----------
-------------PQPYVSQVPFVPQP-RPPAPIQQSPVFPPQTRVPAPAAQQ-------
--------------------------------PPFPFVTQPAV------LGQLPPP----
-----------------LRTHLYPLPSQDPLPPHSGAL-----PFPTPVPP--Q-PRTSA
IPYC-PAPV--SRPQAPSI----------------PSQLPPGTPLPLRGPPPSSQPSPSP
HPV-PSPAPSPGPGP----TTTHPSQAE------------PPPFQ--RCNSSTADLLSSS
PESQHGGSQPPGGGQPLLQPTKADAAEGQRPQALRLIECDPYEQPQRLQQLQEELEAFRG
LLS---------GGAGALDGVWRELQEAQERDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDIMPYDSNR
IVLRSGKDDYINASRVEGLSSYCPPLIATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVAKYFPTERGQPLVQGPLSLVLNSVRTTDT
HVERVMSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIHEVHTHYLHQRPLHT
PIVVH---------C----SSGVGRTGAFALLYAAVQEVEAGNGIPALTQLVRRMRQQRK
HMLQE----KLHLRFCHEAVLRHVEQVLQRHGIAPPSACRPLANPN--------------
----------VAQKAYLPQDPQDLVLGADMPISSIQATIAKLSIRPQGGGQEPPPPPAFP
SPVEPLS--PTPPSLL------------------------------------ELTSPPSP
SPPSSPQQEIPEPKEES-----EVAT---------APSPGPSTSSLELLASLTPEAFSLD
SSLRGKQRMNKQSFLQAHNGQGLR-GAGPSDDPLSLLDPLWTLNKT-
ENSPVAP00000012636 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 750)
-MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGEQVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----IIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLDQKFQ
EAVGQAGAN------M----AVSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEA-NQRLSLEQQLRELIPE
DDITASLVTADHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASFEAYEDLMKKSQEGKDFYADLESKVAALLARAQSTCQARE
AARQQLLD-RE-------------LKKKPPPRPTAPKPLLPRREDGEA-VE---------
-------ADPPEELRSLPPDAFLGTAAA------PRFPAGPFS-----------------
------------------------TSTGPGPHY----LSGPLPPGTYSGPTQMLQPRA--
PPAP------------GHPAMA--------MVPGPAVFPPP---AYAPELGLVSRSSPQH
GVVSSPYGGVGPPP---------------------------------PIAGLPSAPPPHF
S---NPELALGVRPATTTVDSIQAPISSHTAPRPNPTPAA---------PHSCFPVPP--
--------------------SQPVPTPYTY-PLGPKPXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX---------------------------------------------------
--------------------X-------XXXXXXXXXXXXXXX-XXXXXX----------
----XXXXXXXXXX---------XXXXXXXX--------XXXXX---XXXXXXXX-XXXX
XXXXXX------------------------X--XXXX--------------------XXX
XXXXXXXXX--XXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXX------------
-------X---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X---XXXXXXXX-
----XXX-X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
PF00102 // ENSGT00780000121909_0_Domain_8 (1970, 2242)
XXXXXXXXSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKMARYFPTERGQPMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C----SSGVGRTGAFALLYAAVQEVEAGNRLPELSQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPCKPLAGTNVS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSTAACLPGP
V--EPP-------GLPPASLPESVQLPSSS-----------------------------P
PPLSSPLPEAPQ-PEE----EQPVSE---------VPSLEPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSCCAP00000034795 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAI------S----ATSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSICQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AVRQQLLDREL--------KK------KPPPRPTAPKPLLARREESEA-VEA--------
-------GDPPEELRSLPPDMVAAPR-----------PPDAFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPMPPGTYSGPTQLIQPRA--
-PGP--------------S--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSGPYGGIGPAPP---------------------------------VAGLPSAP-PQF
S---GPELAMGVRPATTTVDSIQAPISSHMAPRPNPTPAP---------PQPCFPVPPP-
---------------------HPLPTPYTY-PVGAKQ-PIPT-----QHHFSP-------
-------------------GIPTGFPAPKI--G----------------PRPQPQPQPQP
QPQPQPQPQ--PQPQPH-PSQAFGPQPPQQPLPLQHQHLFPPQASGLL--PPQSP-----
----------------------------------YTYAPQPGV------LGQPPPPLH--
------------T-------QLYPGPVQDPLPPHSGAL-----PFTSPGPPR---PPHPP
LAYG-PAPS--TRPMG----PQAAPLTI-------------------RGPLPAGQPTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQQELEAFRG
QL----------GDMGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVARHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPAGGLESLAASLPGP
AEP---------PGLPPASLPE-STPVP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATRPSDDPLSLLDPLWTLNKT-
ENSNGAP00000023798 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVARDFEGCSVLRK
YLGQLHYLQSRVPMSSGQEAAVTVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPIDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREVMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
EILGQAGA--------G--PSVAKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERTQSICGAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK-----A-PPRPTAPKPLLSRREDSES-AET--------
-------GDPPEELHSLPPDMVAGPR-----------LPNAYLGT---------------
------------TTPLHFPPGPFPSSTGPASHY----FSGPLPSGSYSGPTQPMQPRAA-
----------------------------MPMAPGPALYPAP---TYTPELGLVPRSSPQH
GVVSSPYGGVGPPPP---------------------------------AVGLPSAPPPQF
S---GPELAMAVRPATTTVDSVQAPISSHTAPRPNPTPAL---------PQPCFPVPQPV
PQPVAP--------------PQPLPSPYTY-SVGTKP-HLAGPP--PQHHFPP-------
-------------------SIPTGFPSPRLGPQPPPHP----------------------
-----------------HPSRAFGPQPPQQSLPFQHPHLFPPQAPGILPPPPPYS-----
----------------------------------FPH--Q-PSI-----LGQPPPTLH--
------------T-------QLYPGPSQDTLPPHSGTL-----PFPSPRPPQP---PHPT
LAYG-SAPS--SRPLG----PQVTPVSI-------------------RGPPPASQPTPSP
HLV-PSPAPSPGP----GPVSSRPPTAEP-----------PPCLR--RGAAAAADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQDLETFRG
QL----------GDAGALDTVWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQLMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHETLVRHVEQVLQRHGMPPPGKPLASTSIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSPATSLPDP
AEP---------PGLLPASF-PEPVPVP----------------------------SSSP
PQLSSPLPEAPQPEEEP----P-VPE---------APSSEPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSAMEP00000013618 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------GGAGLASEAA-
AGGGGG--------------GEAV-------PRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 750)
-MIWLD------------------
---LKEAGDFLFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMVKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRELLEDDELLEQKLQ
EALGQAGGS------LA----GSKAELAEVRRDWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQARE
AARQQLLDREL---------KKK-----PPPRPTAPKPLLPRREEGEA-VEP--------
-------GDLPEELRSLPPDMVAGTR-----------PPDTYLGA---------------
------------AAPLHFPPSPFPSSVGPGPHY----LSGPLPPGTYSGPTQVLQPRAPQ
APGH--------------P--------AMAMAPGPALYSAP---AYTPELGLVPQSSPQH
GVVSSPYGGVGPPPP---------------------------------VAGLPSAPPPQF
S---GPEMAMALRPATTTVDSVQAPISSHTAPRPNPSPAP---------PQPCFPVPPPQ
--------------------PQLLPTPYTY-PMGGAKPPLAAAP--AQHHFP--------
-------P-----------GIPPGFPAPR--VG----------------PQP--------
------------------PGVAFGPQPPQQPLALQHPNLFPPQAPGRV--PSQPP-----
----------------------------------YPFAPQPGV------LGQPAPTLH--
------------T-------PLYPGPSQDPLPPHSGAL-----PFPTPGPPQ---SPHPT
LAYG-PAPS--PRPLG----PQAAPLSI-------------------RGPSPASQPTPNP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCVR--RGTA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQQLQRELEAFRG
QL----------GDAAALDAVWRELQDAQEHDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YSLKNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRATET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PVVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPGRPSAGTSVS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSPVASLPGP
VEP---------PGLPPASLPE-SVQLP----------------------------SSSP
PPLSSPQPEAPQPEEEQ----P-VPE---------APSLGPPSSSLELLASLTPEAFSLD
NSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLN---
ENSTSYP00000015284 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEPVPRMP--MIWLD------------------
---LKEASDFHSQSAVKKFVLKNYGENTEAYNEELKKLELLRQNAV-------------R
YLGQLHCLQSRVPMGSGGCCPCH-----------------LNQDLFRQVCGLYSLQPWGT
ALHAGAMDKQVSKEGMK-------
PF03097 // ENSGT00780000121909_0_Domain_4 (445, 645)
CAAGAFAYLGEHFPQAYSL-----------------
-------------------------GQAQECLLEKLMLNNRKSCLVARISAQVVDYYKES
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAPLHMGKQAKEQQKFREQAA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDPARCPSLYYG
---------CHWGK----VQFCC----PHTGHPSACK---RNTLGKPLPVNPTETAVTGP
DIFAKLVPMVAREASLLYREEKAKLLPEMKAKIEDKNEVLDQFMDSMQLDPETVDNPDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1078)
IPPQLKEKCVAFSVRPDTVRNPNQSMQVLLGMFTDVEASLKDIRHLLEEDELLEQKFQ
EAVGQAGAS------L----TVSKAELAEVRREWTN-------------ELHRVMNLHVG
NLRLLSGPLDHVQAALTMPVLTPEDKT-VLQNLKRILAKVQEMRDQRVSLEQQLCELIQK
DDITASLVNTDHSEMKKLLEEQLKKYDQLRVYLEQNLAA------------NVQHAAVRQ
V-LSDLDQKWNSTPQTL----EAYEDLMKKSQEGKDFYVDLESKVAALLEWAQPTCQ
ENSGT00780000121909_0_Linker_7_8 (1078, 1951)
AHE
AAHQQLLDREL--------------KKEPPPRPTAPKPLLPRRAECEA-MEA--------
-------GDMLEELCSLPPDMVAGPR-----------PPDTLLGT---------------
------------AAPLHFPPGPFPGSTGPGPHYVL-------------GPTHLMQPRA--
-----------------------PGSLAMSMAPGPALYPAP---AYTPELGLVPRPSPQH
GVVSSPYAGVGLPPP---------------------------------VAGLPSVPPPQC
S---GPELAMAVRPATTTVVSVQAPISSHMTCFPML------------------------
-------------------LPQPLPTPYTC-PVGAKQPLP---APSAQHQFSP-------
-------------------GLPTGFPVPRIG-----------------------------
-----------PQPQPHSSRAVFGPQPPQQPLPLQHPHLFPPQAPGLLPPQPS-------
----------------------------------CPFAPQPGV------LGQ--------
-------------PPAPLHTQLYPGPSQDPLPPHSGVL-----PFPNPEPPQPSHPCPP-
----------------------------------------PPTPLSIRGPPPTGQLSPSP
HLV-PSPAPSPGPGP----VSPRPLATKP-----------PPC----------LYLLSSS
PESQHGDTQPPGGGQPLLQPTRVDA-------ALWLIERDPYEHPERLRQL---------
-------------------HIWQELQEAQE
PF00102 // ENSGT00780000121909_0_Domain_8 (1951, 2234)
HD---------------NQHQDVMPYDSNH
MVLRSGKVDYINASCVEGLSPYCPPLVATQAPLPGTAAGFWLM----KVSVVVMLVSEAE
MEK-------------------------QKVACYFPMERGQPVVHSALSLALSSVRTTET
HVERVPRLQFRDQSLTRSLVHLHFPTW-PVLGLHD-SPGNLLRFTQKLHAHYLHQRPLHT
PIMVH---------Y----SSGVGRTGAFAPLYAAVQEVEAGNGILELPQLVQCLRQERK
HM-----------LFCHEAAVRHVEQVLQRHSVPPPCKPSASTSIS--------------
------------QKNRLPQDSQDLVLGGDVPISSIQATHAKLTASLPGP-----------
TEP---------PGQPPVSLLESTP-----------------------------IPSSSP
PPIPSSLPEAPQPEEEH-----PVPE---------APISGPPFSSLELLVSLTPEAFSLD
SSLRGKQRMSKQNFLQAPNGQALR-AARPTGDPLSLLDPLWTLNKT-
ENSRROP00000025007 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MPAAMEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKFNSAKKDNDFIYHEVVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQTGAV------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTEHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYGDLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEV-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGSYSGPTQLIQPRA--
-PGP--------------T--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---GPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQP--------
----------------Q-PSRAFGPQPPQQPLPLQHPHLFPTQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQ-----H--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--TRPMG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLYFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSPCAP00000014102 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 740)
-MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELRKLELLRQNAIRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVSVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQLDPETVDNLDAY
SHISPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAMGQAGAS------PA----AHKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTAEEKA-VLQNLKRILAQVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDHKWNSTLQTLVASCEAYEDLMKKSQEGRDFYADLESKVAALLERAESTCQARE
AARQQLLDKEL--------------KKKPPPRPTAPKPLLPRREEGEA-VET--------
-------GDLPEELRSLPPDMVVGPR-----------PPDTFLGT---------------
------------ATPLHFPSGPFPSSTGPGPQY----LSGPLPAGTYSSPAPLLRPL--Q
APGH--------------P--------AVAMAPAPALYANP---VYTPELGLAPRSSPQH
AVVGGPYGGVGPSPP---------------------------------LAALPSAPPPQF
S---GPELAMGVRPATTTVDSVQAPIPSHTAPRPNPAPT-----------QPCFPLPPP-
---------------------QPLGTHYAY-PVGAKQ-PLTAPP--AQHHFPP-------
-------------------RIPTGFPAPRVG-----------------------------
-------------HQSHPSQATFGPQQPQQPLILQHPHLFPPQAPGPL--PPQPN-----
----------------------------------FPFAPQPGV------LGQLPPQLH--
-------------------TQLYPGPAQDPLPPHSGPL-----PFPSPGPPQ---PPHPA
LAYG-PAPS--PRPLG----PQAATLSV-------------------R-PPPVSQPAPGP
HLV-PSPAXXXXXXXXXXXXXXXXX--XX-----------XXXXX--XXXXXXXXXXXSS
PESQHGGSQPPGGGQPLLQPTKVDAAEGCRPQA-RLIERDPYEHRERLWQLQQELEAFRG
QL----------GDAGALDATWRELQDAQEHDARGRSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YSLKNRHQDVMPYDSNR
VVLRSGKDDYINASRVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
VEK-------------------------QKVTRYFPTERGQSMVHGALSLALSSVRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHAHYLHQRPLHT
PIIVH---------C----SSGVGRTGAFALLYAAVQEVEAGRGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGLPPPCKPLAGAGVI--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPAGGLDCPAASLPGP
AEP---------LGLPAVSLPXXXXXXXX-------------------------XXXXXX
XXXXXXXXX-----XXX----XXXXX---------XXXXXXXXXXXXXXXXXXXXXXSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARAEDP--LLLDPLWTLNKT-
ENSCANP00000038846 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVSVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALLCGG
G----PGSLFLFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKLQ
EAVGQTGAI------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------A--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---VPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSA-------
-------------------GIPAGFPAPRI--G----------------PQP--------
----------------Q-PSRAFGPQPPQQPLPLQHPQLFPTQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPTPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--TRPMG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLLPAGLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSMODP00000017672 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MLLP----------LFPHDFRRGVEGWGVVQLASARL---SLVRLSSRLRW
AGGFPGSVTGSSPTPFFEGSGPQPGPAMEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 748)
-MIWLD------------------
---LKEAGEFNFQPAVRKFVLKNYGENPETYNEELKKLELLRQNAIRVPRDFEGCSILRK
YLGQLHYLQSRIPMGLENEAAVPITWTEIFSGKS----VTHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFTYLQEHFPHSYSVDMSHQILNLNINLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVVYYKEA
CRALENPETASLLGKVQKDWKKLVQMKTCYFAAVAHLHMGKQAEEQQKFGERVV------
--------------Y-----FQSALDK----------LNEAIKLAKGQPETVQDALRFTM
D-----VIGGKFNSAKKDNDFIYHEAIPALDTLQPVP---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIDAKNEVLDQFMDSLQLDPETVDNLDMY
NHIPPVLMEKCAALSVRPDTVKNLVQSMQVLSGVYTDVEASLKEIKGLLEEDELLEQKVQ
ETSGQPGAV------PA-------GGLAEVSREWAKYMEVHEKASFTNSELHRAMNLHIS
NLRLLSGPLDQVRAALPSPALSPDDKA-VLQNLKRILAKVQEMRDQRLSLEHQLRELIQK
DDITTSLVTTDRSEMKKLFEEQLKKYDQLRVYLDQNLAAQ-ENVLKALTDANVQYAAVRR
V-LTELEHKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAKGACQARE
AAFQQLLDREL--------------KKKPPPRPTAPKPLLPRKEDGEA-IDP--------
-------GDLPEELRSLPPDMLASHLTAFPPGTL---PSDAFLGA---------------
------------GAVMPFPPGHFT---SQGPHYIPSQGPGPFPPGTYSGPPPLLQPSAPS
LQD----------------------APARPWTPEHRLYPTP---TYTQDPGLIPGSSPQR
GVVSNHYVLGP----------------------------------PGSSGGLPTAPPPRF
I---SPELAPGIRPATTTVDSIQAPISSYTTPRPGPGPSPAQ-------PRPCYSTSQQ-
---------------------GLPAVPYPY-PVGICQPFTPS-S--AQLPFPP-------
--------------------------APRGELQ--------------PQ-----------
-----------PQPQPYTAQVPFVPQP-RPPAPIQHPPVFPPQTRVPAPTAQQ-------
--------------------------------PPFPFVTQPAV------LGQLPPP----
-----------------LRTHLYPLPSQDPLPPHSGAL-----PYPTPAPPPQQ-PRTST
ISYC-PAPA--SRPQGPPA-----------------------PPLPSQFPPGAPSHSPSP
HPV-PSPAPSPGPGP----TTPHPPQAE------------PPP-R--RCNSSTADLLSTS
PESHHGGSQPPGGGQPLLQPTKADAIEGQRPQALRLIECDPYEQPHRLQQLHEELEAFRG
LLS---------SGAGALDGVWRELQEAQERDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDIMPYDSNR
VVLRSGKDDYINASRVEGLSSYCPPLIATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVAKYFPTERGQPLVQGPLSLVLSSVRTTDT
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPENLLRFIHEVHTHYLHQRPLHT
PIVVH---------C----SSGVGRTGAFALLYAAVQEVEAGNGIPALTQLVRRMRQQRK
HMLQE----KLHLRFCHEAVQRHVEQVLQRHGMAPPAACRPLTNPS--------------
----------VAQKAYLPQDPQDLVLGADMPISSIQATIAKLSIRPQGSGQEPPP-VTCP
GLAEPLS--PTTPNLL------------------------------------ELTSPPSP
SPPSSPLPEIPEPEEES-----QAPT---------TPNPGPSTSSLELLASLTPEAFSLD
SSLRGKQRMNKQSFLQAHNGQGLR-GTGPSDDPLSLLDPLWTLNKT-
ENSANAP00000010804 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------WQLTPLIP--ALWEL------------------
----------------AC-------LSTAPYDNRPASPILPLQ
PF03097 // ENSGT00780000121909_0_Domain_5 (344, 416)
NAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGELPD
--PFPMAL----------------------------LPGPASLK---------ASP----
----------------------------------LSQVGGRRS-----------------
----RGPS---------------------------------------R-G----------
-GHSRLSCHSLQVAY-----FQSALDK----------LNEDIKLAKGQPDTVQDALLCGG
GPGFLFFQR
PF03097 // ENSGT00780000121909_0_Domain_6 (670, 746)
VLYNSAKKDSDFIYHQAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_6_7 (746, 783)
LREMAAKIEDKNE----FMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFR
EAVGQAGAI------ST----ASKAELAEVRQEWAKYMEVHEKVSLTNSELHRAMNLHVG
NLRLLSGPLDQVQAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHLEMKMGWVRL----EAL--SVMPTPPSE-DRVLRALTEANVQYAAVRW
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLEHTQSTCQAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1968)
E
AARQQLLDREL--------------KKKPPPRPTAPKPLLPHREESKA-VEA--------
-------AEPPEELRSLPPDMVAAPR-----------PPDAFLGT---------------
------------ATPLHFPPSPFPNSIGPGPHY----LSGPMPPGTYSGPTQLIQPRA--
-PGP--------------S--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
EVLSSPYGGVGPAPP---------------------------------VAGLPSAP-PQF
S---GPELAMGVRPATTIVDSIQAPISSHMSPRPNPTPAP---------PQPCFPVPPP-
---------------------QPLPMPYTY-PVGAKQP----IP--AQHHFSP-------
-------------------GIPTGFPPQP-------------------------------
----------------H-PSQVFGPQPSQQLLPPQHPHLFPPQASGLL--PPQSP-----
----------------------------------YTYAPQPGV------LGQPPPPLH--
-------------------TQLHPDPAQDPLPPHSGAL-----PFPSPGPPR---PPHPP
LAYG-PPPS--SRPMG----PQAAPLTI-------------------RGSLPAGQPTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAA-AAD-LLSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLRQLQQKLEAFRG
QL----------GDMGALDTVWRELQDAQEHDARGRSIA--------
PF00102 // ENSGT00780000121909_0_Domain_8 (1968, 2241)
HRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLMHLHFPTW-PELGLPD-SPSNLLRFIQEVHTHYLHQWPLHT
PIVVH---------C----SSGVGRTGAFELLYAAVQEVEAGNGIPELPQLVQRMRQQRK
HMLQE-----LHLRFCYEAVARHVEQVLQRHGVPPPCKPLASTSIS--------------
--------------QKVRTDSQDLVLGGDVPISTIQATIAKLSIWPPGGLESLAASLPGP
AEP---------PGLP-ASLPE-STPIP----------------------------SSSP
PPLSSPVPEAPQPEEEP----P-VPE---------APSSGPPFSSLELLASLTPEAFSLD
SSLRGKQRMSEQNFLQAHNGQGLR-AMQPSDDPLSLLDPLWTLNKT-
ENSPCOP00000031412 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPETYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAIAVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAS------L----AVSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNILCALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQTR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLARREEGEV-IET--------
-------GDPPEELRSLPPDLVAGPR-----------PPDAFLGT---------------
------------VTPLHFPPGPFSNSTGPGPHF----LSGPLPTGTYSGPTQMIQPRA--
-PGP--------------P--------TMPMAPGPALYPAP---AYTPELGLVPQSSPQH
GVVSSPYGGAGPPPP---------------------------------VAGLPSAPPPQF
S---GPELAMAVRPATTTVDSVQAPISSHTAPRPNPSPAP---------PQPCFPVPPQ-
---------------------QPLPTSYSY-PVGAKQ-ALPAPA--AQHHFSP-------
-------------------GIPTGFPAPRM--G----------------PQPHP------
------------------SQAAFGPQHL----QLQHPHLFPPQAPGLL--PPQST-----
----------------------------------YPFAPQPGV------LGQPPPL-H--
------------T-------QLYPGPSQDPLPPHSGAL-----SFPSPGPPQ---PPHPT
LTYG-PAPS--PRPLG----PQATPLSI-------------------RGPPPAGQPTPSP
HLV-PSPAPSPGP----GPVPSRAPAAEP-----------PLCLR--RGTA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLQQLQQELETFRG
QL----------GDAGSLDTIWRELQDAQEQDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSIRTTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLRFIQEVHTHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCHEAVVRHVEQVLQRHGVPPPCKPLAS-A----------------
---------SISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRSPGGLDSPAASLPGP
AEP---------PGLPPASLPE-STPVP----------------------------SSSP
PPLTSPLPEMPQPEEQQ----P-VPE---------APNLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSRNOP00000052992 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVAITWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMLAKIEDKNEVLDQFMDSMQLDPDTVDNLDAY
NH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQ
ETLGQAGAG------PG--PSVTKAELGEVRREWAKYTEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSLCRAQ
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KKK-----APPPRPTAPKPLLSRREEGEA-AEA--------
-------GDQPEELRSLPPDMMAGPR-----------LPDPFLGT---------------
------------AAPLHFSPGPFPGSTGPATHY----LSGPLPPGTYSGPTQLMQPRAA-
----------------------------VPMAPGPVLYPAP---VYTSELGLVPRSSPQH
GIVSSPYAGVGPPQP---------------------------------VVGLPSAPPPQF
S---GPELAMAVRPATTTVDSVQAPISSHMAPRPGPAPAP---------PQPCFPVPQPV
PQSVPQPQPLPTPY--------------TY-SIGTKQ-HLTGPL--PQHHFPP-------
-------------------GIPTSFPAPRIGPQPPPQLQPQPQPQPQPQ------PP---
-------PQPQPQPQPQPQRPVFGPQPTQQPLPFQHPHLFPSQAPGILTPP--PP-----
----------------------------------YPFTPQP-GV-----LGQPPPTRH--
------------T-------QLYPGPPPDTLPPHSGAL-----PFPSPGPPHP----HPT
LAYG-PAPS--PRPLG----PQATPVSI-------------------RGPPPANQPAPSP
HLV-PSPAPSPGP----GPVPSRPPTAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIEQDPYEHPERLQKLQQELESFRG
QL----------GDAGALDAVWRELQEAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPIERGQPMVHGALSVALSSVRTTDT
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPGNLLRFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGSGIPELPQLVRRMRQQRK
HMLQE----KLHLKFCHEALVRHVEQVLQRHGVPPPGKPVASMSVS--------------
------------QKSHLPQDSQDLVLGGDVPISSIQATIAKLSIRPLGGLDSPAASLPSL
VEP---------PGLPPASLP-EPTPAP----------------------------PSSP
PPPSSPLPEPPQPEEEP----S-VPE---------APSLGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AAQPTDDPLSLLDPLWTLNKT-
ENSMGAP00000001186 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------
PF03097 // ENSGT00780000121909_0_Domain_4 (318, 750)
QFVLKNYGENPENYNEELRKLEVLRQSAVNVPRDFEGCSTLRK
YFGQLHYLQSRIPMGAEQEAAVPIAWTEIFSGKT----VTHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFTYLRDHFPHSYSVDMSHQILNLNINLMLL-
W-----------------------QGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENSETASLLGKIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVI------
--------------Y-----FQSALDK----------LNEAIKLAKGQPETVQEALRFTM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQSVK---GAPLVKALPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLRDVMAKIEAKNEVLDQFMDPMQLDPETVDNLDMY
SHIPPILMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKEIRDLLEEDEAQERKLQ
ELLGKGSVP------QGSPPPASSTGLAEVSKECSKYMEVHEKASFTNTELHKAMNLHIG
NLRLLSGPLEQVRAALPSPTLSEDDKQ-VLQNLKRILGKVQEMRDQRMSLEQQLREMIQK
DDITTSLVTTDRSEMKKLFEEQLKKYDQIKVYLEQNLAAQ-ENILKALTDANVKYAAVRK
A-LAEVEHKWNTTVQTLVASYEAYEDLMKKSQEGKDFYTDLEGKAAKLLEKARAACQAAE
ANRQQILEKNA-------------MGQPGRGRST--------------------------
------------------------------------------------------------
------------------------------LGC----SVEAL------------------
---AS-------------------------------------------------------
VPEPSPQGAVSAPCWV--------------------------------------------
------------------------------------------------------------
--------------------E--------M-GD---------------------------
-SQDE-------------------------------------------------------
------------------------------------------------------------
---------------------------------------LPMLIPTPSCQGNEEA-PTPS
SHS------------------------------------------------------PQ-
---TLPAEE--AI--G--------------------------------------------
-------------AGSRGARGGRPPPAGLP---------------------GLGHLLSSS
PESQHGGSK-AAVGQPLLQPTKADAKEGQKPKAVQLIENDPYEKPERVLRLRAELERFRA
LLQRLEQTEP--GGTAELDALWKELQDAQERDARQLSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2201)
YSMKNRHQDIMPYDRNR
VVLRSGKDDYINASRVEDLSPYCPTIIATQAPLLGTAADFWLMIYEQKVSVVVMLVSEQE
LEK-------------------------QKVLRYFPTERGQPVVQGPITLVLSSVKAAPT
HVERMITLQYRDQSLKRTVIHLQFTSW-PELGLPD-SKASLLRFIQDVHGHYLHQRXQDL
VLGGD---------V----PISSIQ-ATIAKLSIKPPGGVEGGAVPVLPDAVTDGGTGTD
GG-------------------------TAADGVCAPNPEPVP------------------
---------------------------------------------EPPGDA---------
------------------------------------------------------------
-ESSNH--------VE----EIPPPA---------PAAPPAPTSSLELLASLTPEAFTLD
ASLKGKQRMNKQNFLQAQTGEGLR-APRPSDDPLSMLDPLWTLNKS-
ENSMLEP00000009742 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQTGAT------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------A--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---SPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQPQP------
--------------QPH-PSRAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPTPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--ARPVG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPISSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSMNEP00000002053 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALLCGG
G----PGSLFLFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQMGAT------S----VPSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-MEA--------
-------GDPPEELRSLPPDMVAGPR-----------LPDTFLGT---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------T--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGLPSAPPPQF
S---SPELTMVVRPATTTVDSIQAPIPSHTAPRPNPTTAP---------PQPRFPVPPP-
---------------------QSLPTPYTY-PVGTKQ-PVPA-----QHHFSP-------
-------------------GIPAGFPAPRI--G----------------PQP--------
--------------QPH-PSRAFGPQPPQQPLPLQHPHLFPPQAPGLL--PPQSP-----
----------------------------------YSYAPQPGV------LGQPPTPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PAPS--ARPVG----PQAAPLTI-------------------RGPSPAGQPTPSP
HLV-PSPAPSPGP----GSVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGSTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLHFIQEVHAHYLHQRPLHT
PIVVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PPLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-ATQPSDDPLSLLDPLWTLNKT-
ENSCAFP00000042483 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEAVPRMP-
PF03097 // ENSGT00780000121909_0_Domain_4 (277, 748)
-MIWLD------------------
---LKEAGDFLFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPHAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFAM
D-----VIGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLR
ENSGT00780000121909_0_Linker_4_7 (748, 782)
EMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
S
PF13949 // ENSGT00780000121909_0_Domain_7 (782, 1081)
HIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRELLEEDELLEQKLQ
EALGQAGAS------LA----GSKAELAEVRRDWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALTPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLRVYLEQNLAAQ-DNVLRALTEANVQYAAVRR
V-LSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVAALLERAQSTCQARE
AARQQLLDREL--------------KKKPPPRPTAPKPLLPRREEGEV-LET--------
-------GDLPEELRSLPPEMVAAPR-----------PPDAYLAA---------------
------------AAILRFPPSPFPSSAGPGPHY----LSGPLPPGAYSGPTQGLQPRPPQ
APGP--------------P--------AVVLAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYGGVGPPPP---------------------------------VAGLPSAPPPQF
S---GPEMALGVRPATTTVDSVQAPISSHTAPRPNPSPAP---------PQPCFPVPPPQ
P--------------------QLLPTPYTY-PMGAKLAHIVPPA--LQDIATGNTTII--
------------------------------------------------------------
---------------------------PVLKLPLQ-----------------DGS-----
----------------------------------WGYPYWIME-----------------
-----------------------------------------KRNFPVPGLN---------
------------------------------------------------------------
----------------------------------------VSCPE--RTGHRMSE-----
-------------------------------HVIGAI-----------------------
------------------------------------------------------HYCPYK
KVLKSGSEDLQELR----------------------ARHLFLVIYRGYILVILKIL----
-------------------------------------------------------RX---
---------------------PRRDCW-GTS---------------------L-----NP
RARRP---------C---------------------------------------------
AVDQTEGPLQLHLRFCHEAVVRHVEQVLQRHGMPPPGRSSAGTSIS--------------
------------QKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLDSPATSLPVP
VEP---------PGLPPASLPE-SAQLP----------------------------SSSP
PPLPSPLPEAPQPEEEQ----P-VPE---------APSVGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKQNFLQAHNGQGLR-AARPTDDPLSLLDPLWTLNKT-
ENSXETP00000056989 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------
PF03097 // ENSGT00780000121909_0_Domain_4 (318, 750)
QFVLKNYGENPENYNEELKKLDQLRQSAVNVPRDFEGCSVLRK
YFGQLHYLQSRIPMGSEQEASVPVTWTEIFSGKT----VTHEDIKYEQACVLYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLRDHFAHSYSVDMSHQILNLNINLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENSETASLLGKIQKDWKKLVQMKIYYFASIAHLHMAKQAEEQQKYGEQVA------
--------------Y-----LQSALDK----------LNEAIKQSKGQPATVQEALRFTM
D-----VIGGKFNSAKKDNDFIYHESVPALDTLQAVK---GAPLVKALPVNPTDPAVTGP
DIFSKLVPMAAHEASSLYSEEKAKLLREVMSKIEAKNEILDQFTDSLQLDPDTVDNLEMY
SHIPPALMEKCAALSVRPDTIKSLVQSMQVLSGVYTDVEASLKDVKEILDEHEIQEKKLQ
EEVGKQPAP------P----APLSPSIEDVSKEWGKYMEVHEKASFTNTELHKAMNLHIS
NLRLLSGPLDQLQQQLPAPVLTEDDKA-VLQNLKKILNKVQEMREQRQSLEQQLRDTIQQ
DDITTSLVTTDRSLLQKLFAEQLKKYDQLKVYVEQNLSAQ-ENILKALTEANVKYAPVRK
I-ITEAEQKWNHTVQTLISSYEAYEDLMKKSQEGKDFYSDLESKVAKLVEKSRAAFDAAQ
ANRQQVLERRE-------------LKKRPPPRPTAPKPALQKKPSDVD-LASLPLSDLAS
LQHSLFYSELPEELKSLPPEALLAHLDRLSADTLDAFPPDPTYGGTKPTGVNAYRPSRTA
SAPVADPHSVPFTQSPHFNPMPGHTPQYGGVGY----PANAFPPVMYNGNPQLSQFKQSA
PPQANVPQAPVSSSSPQNPRMYLAGAMGRVHVQPEAVPMPP---AYAPGTMPQQRVSPQH
VPMPATAAAPVAPQFNTGVGFAVGQQVSSSGVLPNAVNYSAAGYAPQGSPRIHSTAPVSG
L---QPQAAQGIRPATTTVNSIQGPISSYTTPRLPGPNQTITPTLPPIRAQSGYMAPPVH
-------------------SAMGQPAPYGC-PQGAVPQYPQPPRPILPHAQPPQLFQAPG
QTQHRLDSARPPSVPNQQQYAPPPQPP-----------FSAQMRPPLNHPQPPIYQ----
-------PPVVPQVTPVPAQP-------HFQQHFHHQNPFPVQ-PGILPLQPGAQPHVPP
QLGPQRFPVASHDKLPPQSLPPHSAGMNFPGTVPRPAAPMAQPIPPPMCQATPQIHPHPA
AVSMHS------------------------TPPGLNAPIASAMPFVPPARPT--VPPPNS
LANQMPALN--QMPMGGPQATPAIPHHIQAPSSPAMSHLPGAVIVSGAAAMPSPAPSPQP
SLVLQSQTSLPTTGPATATIPQRPPPSLTPGTTPLTQGSGEVVFQ--RQSSSTDDLLSSS
PESQHGSSK-TSVGQPLLQPTKADLKEGQKPKAIQLIENDPYEKPEHVMRLLSELDRFRV
VVEALDKPVP--GASTQLDSMWKEFQEAQEKEARQQSIAIARC
PF00102 // ENSGT00780000121909_0_Domain_8 (1964, 2242)
YTMKNRHQDIMPYDKNR
IILQSGKDDYINASKIEDLSSYCPSIIATQAPLVGTASDFWLMIHEQKVSLIVMLVSEQE
IEK-------------------------QKVLRYFPLERGQAMVHGHISLTLTSQKVTDI
HVERVLSLQYKDQSLKRSIIHLQFTSW-PELGLPD-SKGNLLRFIQEVHSHYLHQRPLHT
PIVVH---------C----SSGVGRTGAFCLMYAAMQEVEAGNGIPDLAELVKKMRQQRK
YMLQE----KIHLKFCYEAVLKHAEQVLQRHGVCTPSSSKPQHSTP--------------
------------LKLYTVQDPQDIVLGGDMPISSIQATIAKLSIKPCPGGTENPASYQLP
PTLDSWANEPATSNVLPPEVPSSTPQPDLTPMAVSMEYQPSQTLPPAAANGNSVLLTESA
ADVSNHLPMAAGEAVP----KAEPPP---------VTSTTASSSSLNLLASLTAEAFNLD
SAQKGKQKMSKQNFLQPQNGGGLVRGSMAADDPLSMLDPLWTLK---
ENSOARP00000004361 (view gene)
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-------------MGSGQ
PF03097 // ENSGT00780000121909_0_Domain_4 (379, 593)
EAAVSVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFSYLREHFPQAYSVDMSRQILTLNANLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVSEPGPGG
HSAVSSPVGSPAGGWSPLSPWVPAVPGDRRGRLPSEWLPGGVH--CGQ--SRKQTLTLVL
WAGWRVVVA---------------------------------------------------
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ENSSHAP00000009643 (view gene)
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---------------------------MQTFPGVV--QLFLC------------------
---L---YPFVLYC
PF03097 // ENSGT00780000121909_0_Domain_4 (315, 748)
TVEQFVLKNYGENPETYNEELKKLELLRQNAIRVPRDFEGCSILRK
YLGQLHYLQSRIPMGLENEAAVPITWPAQRIPKYLRPQLRSTHISLPDLNFPFCKGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFTYLQEHFPHSYSVDMSHQILNLNINLMLLG
KVSRILKGIPYSRVQPNWAGPQMPRGQAQECLLEKSMLDNRKSFLVARISAQVVVYYKEA
CRALENPETASLLGKVQKDWKKLVQMKTCYFAAVAHLHMGKQAEEQQKFGERVV------
--------------Y-----FQSALDK----------LNEAIKLAKGQPETVQDALRFTM
D-----VIGGKFNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIDAKNEVLDQFMDSLQLDPETIDNLDAY
NHIPPVLMEKCAALSVRPDTVKNLVQSMQVLSGVYTDVEASLKEIKGLLEEDELLEQKVQ
EASGQSGAV------PA-------GGLAEVSREWAKYMEVHEKASFTNSELHRAMNLHIS
NLRLLSGPLDQVRAALPSPALT--------------------------------------
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ENSPTRP00000025639 (view gene)
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---------------------------MEAVPRMP--
PF03097 // ENSGT00780000121909_0_Domain_4 (278, 746)
MIWLD------------------
---LKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRK
YLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKS----VAHEDIKYEQACILYNLGALHS
--MLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLML--
-------------------------GQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEA
CRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVA------
--------------Y-----FQSALDK----------LNEAIKLAKGQPDTVQDALRFTM
D----V-IGGKYNSAKKDNDFIYHEAVPALDTLQPVK---GAPLVKPLPVNPTDPAVTGP
DIFAKLVPMAAHEASSLYSEEKAKL
ENSGT00780000121909_0_Linker_4_7 (746, 783)
LREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAY
SH
PF13949 // ENSGT00780000121909_0_Domain_7 (783, 1080)
IPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQ
EAVGQAGAI------S----ITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVG
NLRLLSGPLDQVRAALPTPALSPEDKA-VLQNLKRILAKVQEMRDQRVSLEQQLRELIQK
DDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQ-DRVLRALTEANVQYAAVRR
V-LSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAR
ENSGT00780000121909_0_Linker_7_8 (1080, 1967)
E
AARQQLLDREL--------KK------KPPPRPTAPKPLLPRREESEA-VEA--------
-------GDPPEELHSLTPDMVAGPR-----------LPDTFLGS---------------
------------ATPLHFPPSPFPSSTGPGPHY----LSGPLPPGTYSGPTQLIQPRA--
-PGP--------------P--------AMPVAPGPALYPAP---AYTPELGLVPRSSPQH
GVVSSPYVGVGPAPP---------------------------------VAGFPSAPPPQF
S---GPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAP---------PPPCFPVPPP-
---------------------QPLPTPYTY-PAGAKQ-PIPA-----QHHFSS-------
-------------------GIPAGFPAPRI--G----------------PQPQPQPHPH-
-------------PQPH-PSQAFGPQPPQQPLPLQHPHLFPPRAPGLL--PPQSP-----
----------------------------------YPYAPQPGV------LGQPPPPLH--
------------TQ-------LYPGPAQDPLPAHSGAL-----PFPSPGPPQ---PPHPP
LAYG-PATS--TRPMG----PQAAPLTI-------------------RGPSSAGQSTPSP
HLV-PSPAPSPGP----GPVPPRPPAAEP-----------PPCLR--RGAA-AADLLSSS
PESQHGGTQPPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRG
QL----------GDVGALDTVWRELQDAQEHDARGRSIAIARCYSL
PF00102 // ENSGT00780000121909_0_Domain_8 (1967, 2241)
KNRHQDVMPYDSNR
VVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAE
MEK-------------------------QKVARYFPTERGQPMVHGALSLALSSVRSTET
HVERVLSLQFRDQSLKRSLVHLHFPTW-PELGLPD-SPSNLLCFIQEVHAHYLHQRPLHT
PIIVH---------C--S--SGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRK
HMLQE----KLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ-------------
-------------KNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGP
AEP---------PGLPPASLPE-STPIP----------------------------SSSP
PHLSSPLPEAPQPKEEP----P-VPE---------APSSGPPSSSLELLASLTPEAFSLD
SSLRGKQRMSKHNFLQAHNGQGLR-ATRPSDDPLSLLDPLWTLNKT-
{"MGP_PahariEiJ_P0025938": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMAUP00000023896": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSODEP00000017802": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSACAP00000000753": [["Domain_6", 618, 748, "PF03097"], ["Domain_8", 1966, 2241, "PF00102"]], "ENSMOCP00000011024": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMLUP00000014180": [["Domain_4", 277, 750, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSFCAP00000014352": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMPUP00000014910": [["Domain_4", 406, 748, "PF03097"]], "ENSPPAP00000039642": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSDNOP00000019056": [["Domain_4", 277, 748, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSACAP00000020854": [["Domain_4", 318, 739, "PF03097"]], "ENSTTRP00000002133": [["Domain_4", 277, 750, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSBTAP00000003600": [["Domain_4", 277, 748, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSOGAP00000016953": [["Domain_4", 277, 748, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSSTOP00000014280": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSTSYP00000013758": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSJJAP00000023313": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1077, "PF13949"], ["Linker_7_8", 1077, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMMUP00000018455": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMFAP00000045862": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSOCUP00000002733": [["Domain_0", 2, 93, "PF07707"], ["Linker_0_1", 93, 133], ["Domain_1", 133, 173, "PF01344"], ["Linker_1_2", 173, 177], ["Domain_2", 177, 222, "PF07646"], ["Linker_2_3", 222, 227], ["Domain_3", 227, 286, "PF07646"], ["Linker_3_4", 286, 315], ["Domain_4", 315, 748, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSAPLP00000013471": [["Domain_4", 318, 750, "PF03097"], ["Domain_8", 1964, 2251, "PF00102"]], "ENSMPUP00000012037": [["Domain_4", 343, 746, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMEUP00000000922": [["Domain_4", 277, 750, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSEEUP00000008564": [["Domain_4", 319, 658, "PF03097"], ["Domain_8", 1964, 2337, "PF00102"]], "ENSCLAP00000023846": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2225, "PF00102"]], "ENSRBIP00000019063": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMICP00000012451": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "MGP_CAROLIEiJ_P0090260": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSSARP00000007700": [["Domain_4", 277, 630, "PF03097"]], "ENSCPOP00000020712": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSCGRP00000016169": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSCGRP00001015493": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSHGLP00000016353": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSFALP00000002180": [["Domain_4", 350, 748, "PF03097"], ["Domain_8", 1966, 2241, "PF00102"]], "ENSSSCP00000042659": [["Domain_4", 424, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSECAP00000014531": [["Domain_4", 277, 748, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSPPYP00000015571": [["Domain_4", 277, 748, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSCHOP00000001366": [["Domain_4", 277, 750, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSGGOP00000003045": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSCAPP00000017381": [["Domain_4", 318, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSTBEP00000011513": [["Domain_4", 277, 813, "PF03097"]], "ENSGALP00000051392": [["Domain_4", 342, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1078, "PF13949"]], "ENSHGLP00100024238": [["Domain_4", 316, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSCHIP00000005775": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSPEMP00000019951": [["Domain_4", 278, 581, "PF03097"], ["Linker_4_6", 581, 669], ["Domain_6", 669, 746, "PF03097"], ["Linker_6_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSOPRP00000004849": [["Domain_4", 319, 750, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSFDAP00000013567": [["Domain_4", 316, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1081, "PF13949"], ["Linker_7_9", 1081, 1967], ["Domain_9", 1967, 2043, "PF00102"], ["Linker_9_8", 2043, 2126], ["Domain_8", 2126, 2241, "PF00102"]], "ENSPANP00000003607": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSLAFP00000013573": [["Domain_4", 277, 750, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSNLEP00000007674": [["Domain_4", 278, 739, "PF03097"], ["Linker_4_7", 739, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSCJAP00000051721": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSP00000265562": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSSBOP00000000750": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSANAP00000024448": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2224, "PF00102"]], "ENSCATP00000025642": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMUSP00000039580": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "MGP_SPRETEiJ_P0093987": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSCSAP00000012103": [["Domain_4", 277, 748, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSSHAP00000008711": [["Domain_8", 1967, 2241, "PF00102"]], "ENSPVAP00000012636": [["Domain_4", 277, 750, "PF03097"], ["Domain_8", 1970, 2242, "PF00102"]], "ENSCCAP00000034795": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSNGAP00000023798": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSAMEP00000013618": [["Domain_4", 277, 750, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSTSYP00000015284": [["Domain_4", 445, 645, "PF03097"], ["Domain_7", 783, 1078, "PF13949"], ["Linker_7_8", 1078, 1951], ["Domain_8", 1951, 2234, "PF00102"]], "ENSRROP00000025007": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSPCAP00000014102": [["Domain_4", 277, 740, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSCANP00000038846": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMODP00000017672": [["Domain_4", 277, 748, "PF03097"], ["Domain_8", 1967, 2241, "PF00102"]], "ENSANAP00000010804": [["Domain_5", 344, 416, "PF03097"], ["Domain_6", 670, 746, "PF03097"], ["Linker_6_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1968], ["Domain_8", 1968, 2241, "PF00102"]], "ENSPCOP00000031412": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSRNOP00000052992": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMGAP00000001186": [["Domain_4", 318, 750, "PF03097"], ["Domain_8", 1964, 2201, "PF00102"]], "ENSMLEP00000009742": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSMNEP00000002053": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]], "ENSCAFP00000042483": [["Domain_4", 277, 748, "PF03097"], ["Linker_4_7", 748, 782], ["Domain_7", 782, 1081, "PF13949"]], "ENSXETP00000056989": [["Domain_4", 318, 750, "PF03097"], ["Domain_8", 1964, 2242, "PF00102"]], "ENSOARP00000004361": [["Domain_4", 379, 593, "PF03097"]], "ENSSHAP00000009643": [["Domain_4", 315, 748, "PF03097"]], "ENSPTRP00000025639": [["Domain_4", 278, 746, "PF03097"], ["Linker_4_7", 746, 783], ["Domain_7", 783, 1080, "PF13949"], ["Linker_7_8", 1080, 1967], ["Domain_8", 1967, 2241, "PF00102"]]}