ENSGT00780000121902_3 : Linker Region Query Results

-------MNLWR----PSFLVFFAVTSEGLLIEPQEGSVAGGTWITITLDDSASHELEHL
SPASWPHLEVSLVN-----ADLPMLPCDVSPVY--FDLSTIRCRTRRPL-RSSPQEGLYY
VEVSFKGRVINNLTGVEKENYAFKFSAEQTPVVYQISPPSGIPGNLIEIYGKTFAGRYET
LDFNVDYIDGPAVLVA---------EGDGWTSLCSFADGQAGSIYSIQTKEGLGTMQCRV
EGNH-IGSHNVSFSVFNKGK-SVIDKD-AWLISAKQE----LFLYQTHSEIASVFPVAGS
LAGGTDLTITGDFFEEPVQVTAAGVPCKVKRV--SPRQIICTTEAVGRSRMLGASQPGNR
GLLFEVWDDA--SDLTEAGPGYRWQFVPNAQSPVRFLSAAKQSFSSRLRGFFVAPQTNNY
TFWIQADGPASLYLSSSQDPQHKV-RIASLPSGNLEWSGKWVKNW----SESWQPKSQKF
ELTAGLRYYLEALHHGKAPSNGMRVGVQIHNTWLNPQVVNNYYTERHEIRAHALYLPDVQ
MLTVSG-TGWFSISWSNAPRRMIHTNSTALQVQTAIEELLSVGCDIEPTSAKILFHDGFE
KEG---SNVTKHVVYGTEPFCGRFSARSPSQLVKATPSSLLRYDLTEYTHVCFAHKGHMS
NILHISVSYTNISLSSMERNLTCQWDF----NGTDPTSWTFSCTDLWTGCVSRSVPLQDL
PINTPVFVHQIDLLSI-QQKETAGLFYLDEVIITDRAVTVSQRDPKPRRLGGQIIEAVTV
VGSSPTYNVSWLVSGCGASLSLLSLRGAVLCEGSEEDDHLY--------VSTEDRLQVSS
PPLGGTFCIHLGS-TVISDVSVHISSHQLRRLLQTNTDSSTAPYFNTSDFIVTKDSETCY
ESIWTLTWRTKAGDLPNVIN---VSAENLTGLKPAVSSRVVYDGGVFIGPIFGDMLATSN
NKTQVVVVVNDVPASCSGSCSFQFSQEMTPLVSDVEYSADDRF---QATVVIRGVGFSEE
STTLQVQVKNKTCNIIMSDQTKVVCKMERLPLGVHQLALLVRPYGFALNASTGEGIFLRV
EPRLVA-IEPPRASEIGGLRVALKGTGLEGVNLVLFGSQPCPVLEDTRSSTQIECKVPSR
GAED-AAVHVTLVSGYQSTTVTNLFQYDPSLNPAIVSLSRNRSGLA--GGRELQIGISS-
-FASYRGSDIKVQIGGVWAQIQVQMDNGLNVTLPGLAVGWYNVSVIINGVAIASNRVEPL
IHYISEVFSIEPCCGSFLGGTLLTISGLGFSQNRSLVSVSINEQTCLVTHLAEETIWCLT
PPAANFSN-EVSQD--VPVRVNILVSNSSLQNVP---VAKSI-TFNYQRALTPLVTTVDV
EILESSMLLSIQGVNITGSVAKLGDSECELELQRG------------NESAMFYECSLPL
SNLEPGIYPIQVIQRQLGYSHVTARLQTITVT PRITSIFPSDGSICGGMLLTISGI-ALR
SRRDLEQVSLD--GNYSCELQSSDDNTIKCVVLSETHLLPYRWWAEVSWAL----NVTVT
VNGISSVCPGDCTLHLREQSTPLVDVVTWETNGMYTDVTIKGQRLAWPGDSPVVHVNDQA
VCKVTFWNET-SIRCQMGCIAPGEHNISISNRRSGQACFRSTSSVLTVTPQVHQFYPQNF
STNGGGLLTFAGAALKGKSRTSVLIGQQPCLILNV-TCIAIQCTVPPGNGARALRLTVDA
ISYDIGEISYSEESTPTFLSFAVTG-LLLTINVSQVMETDAIHVFVGDSACRGVTI----
THSELQCSPPLLPAGEYPVLGLHVPRGWASSNLTFISQLMVTAVRCNWG-GLNGGVVHLH
GTGFSPAQTSVTICGSPCEMLGNATTTSLSCLAPRLQASLAFLCSLTHSSANCQEDRSTI
IKCDVQVMVGSYCQQGPRSYLYLCGESQAFLFAPAHWCVFLIDDTPFNLPSR-FSPKVER
DEVLIYNSSCNITMETEAEMECEGANQPITAKITEIWKNWGQNTQENSHTLFCFTKRRKK
NFFKSPLAQDKDNHTCENGQFFLLNFNVNTANYLLSSSGGKLVFTGPGPVELHAHYILIS
DGGELRVGSSTARFHHRAHIYLYGSLHSPPLFPYGAKFLAVRNGTLSIHGWMPKVTFTYL
KSSALANDLRLVLQKPVDWEPGDEIV-VGRTGLGDAQQQEEVAIIESINNTELYLRSPLR
YSHSVGEERVNGQSLPLTAVVALLSRRVVVQGNVTKERISHVRECAEAGSTRGG-SRCLY
GRSERQLGSRDLGAVVIVEAFQGATSQLQVEGVQFHHMGQAFWQRRSALTVAGNTQMADS
YIRGCCLLDSF-GQGLRLTGISNLSVDSNVFFNISGHGLLLVFTCSVSFYFIE---YKCK
HNLKR--SGLEKGNRIRNNIVIGLSATDGLSNIETLSPAGIYIRAPANHIEGNTVCAAGY
GYFFHLSPEGPSKMPLLSFSENTAHSCTRHGLLVYPEYLPDS--PNSPVQFNSFTVWSSQ
GGVQI-FSSSNLKLQNFRIYACMDFGIDIIESLGNTTVANSVLIGRIGQE---DKTCMSA
GLKTPKRFQLFVSNTAFRNFDMSTCTAIRTCSGCYQGQGGFTVRLEHL--TFTNSPFQVS
FPFPHAAILEDLDGSVTGKEGSHILPYTDILVASCTTSANFSQALGGCVCSKDLVFHRMS
LHLREAPEIPYNLTVIDSRNKTTTVNYVPDTLSNLHGWMCLLLDKETYTLTFD-SPLVS-
KQLQYSVTFSNFTTGNYLLVEHKD-LPAQL---EVVVSCGKRTGQPLQSLPSYGHHRNCD
WYLDSTLRKLTYLVTGADLIHLELKEKE--R--APSPTSDPSDSVLKWSHPETWKDVEKG
WGG--FNCSIPGPGEDVIILPNRTILVDTDLPPLRGLYILGTLEFPTNSSNVLSAACIVV
VGGTLNV--GSFQHPLERDSKLLILLRASEGIYCDHLEEINVHPGSIGVYGKMQMYSSYP
GKSWTHLGASVAPGNERILLEDEVDWRPEGDIVISSSSYEAHQAELVTLKEVSGHSITLH
ERLLHRHIGHPHDIEDGRRIPLSAEVGLLTRNIQIKSDVPCTGKILVGHFTDSSGREFEG
VLQLLN---TEFLNFGPPQLSAIEFRNVTQQSSVVSSTIHGSCGVGIKAVMSNGIWLHDN
IVFNTVGPGIDLEGKNHSLIRNLVILSRQPESLLNWVAGIKVNLVIGVSLYGNVVAGSER
IGFHIKGQECLLDVDYCSENVAHSNLHGIHLYRGDGFQTCTRITGFLSYKNYDYGMMFHL
GSSVIIDNVVLVDNTVGLLPVIHCLYAKQCYTGKRHIELRNSTIVATSSTFDCIRDRIKP
QAADLTSRDRPPHYLQRGRAGILWPKFTTVTSQRPDNPWHKI-VLCPKVLGLMKLK-DVT
FTGFTKSCHSEDRDVCIMSDTDHLGIMPLITAERSRMLHVNEKDKFYFHAAS--VQTSED
TTFPEKSCEGSRKVLIKDLDGNLLDLEPPVSVIPKSEFEWTRFYLQ--SGIYRDDSKCIF
KPSVQGYFCKQADYAFVILENLDTSTVKQELFPIAAVTGSFMDTFSDGASDASCRSAQHP
SAFFSVLPTTKLTTVCFPGLTPLIFRLYLLSGQNSTKLPLAIFYNEPLSLRVFTEGKYIS
PTPS---SFSWNVGAGTNYFSFEDNLLYVLLHEEEPVEIITGLSLHVAFTVTETTGEEGE
-ANIMHRLADFLQVGHDQVRIVYRVPGGESMLKVISDNASKKKYHCPNMTFCTAFHSRSG
SQKQGRGAVNA--RVVQLSDAAGPSKVLIFEFGDPPGHQINEFQRSLTIDNLKILASAII
NAHQTGDLQTVLGLPVDSIMV-TSSRSVLSVHVKQNGSRQHLGTCLYVRPYSISVHVQPS
DGEIEKQLPVQPQIVFLDKKGRRVDTVGPPSEPWVISAHLKGSSEAVLR--GLT-EVQVI
GGCASFSNLAVSSSGTNWNLVFTVTSPP-GAKFTVLSQPFTIFPVPAGEKASLILVVLMS
AIASAFV-VTLVLCWFKKSKN---------------------------------------
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------AMPGWVSSLMSVQVLLLSAPHLSLRIQPDAGSLAGGTWLTITCDGLD---PGVL
YPRNGSQLEISLVSV--AAPALPGVPCDVTPVF--LEAPVVMCQTRSLL--SEAYEGLYS
LEVRSGGQVVCSPGPGPQDNCTFKFSKAQTPVIHHVNPSSGVPGKLIHVDGWIITGRLET
FDADAEYIDSPLVLEA---------QGEEWITSCSLIDRHTGGHYPLWEDRGLGTLTCRV
EGDY-IGSQNISFSVFNKGR-SMVNKS-AWLVSAKQE----LFLYQTHSEILSVSPEMGS
LGGRTDLTITGDFFDSSAQVTVAGLPCDISHV--SPRKIECSTRAPGKGARLAAPQAGNR
GLVLEVGDAAEGLELTEATPGYRRQTVPEASSSYGFWSKERQPFRARLRGFFVAPETNNY
TFWIQADSQATLHFSRSEDPSTKV-KVASIRVGTAAWFDSWEQKG--TDEGTWQQKSPKM
ELLGGARYYLEAEHHGTAPSSGMRVGVQIHNTWLSPDVVTTYLREKHQISVRAQRLPEIQ
MLKVPG-KGDFFLTWDNASSQPLPANATAHQIQATIEKLLAIKCNLEPLSVNILLRLGFE
QGL-EGSSSDGDLTRRTEPFCGRVCLRQPRRLDLLRTAAQKGYRLEQYPHLCLAYKGHRN
TVLRVTVSFVIGFQNIT-KNSTCDWSL----PGASPKSWQFACTDLRNMCAHGSRDLQLP
LADTPVLVQQVALLSLA---QETGLLYLDEIIISDTNLTVSQDDSATTRPGGNLVESVSV
LGSHPVYNVTSWTAGCGAELPLIAARSVPTEGA-E---------ASGLVQGTAQRLQKTS
PPLGGRFRIHLPN-TVIPDVPVHVSAGHLHKLLQDSADGFTSRYLGVSDFVVEEDRSSCY
EHVWTLAWSTQVGDLPNLIE---VSDQNLTGVNPVVALRVVYDGGVFLGPIFGDMLATAH
QHAQVVVRVNDIPALCLGSCSFQYLPGLTPRVHSVWCSLDGDT---NLLVYITGTGLSGD
SKSLQVMVNQTSCKVIFSNQTLVVCQTDLLPVGVHQVSVLVRPSGLAVNASG-EGLFLHV
EPRLDV-VEPSRAAEIGGLWATIWGSSLESVSLVFFGSQPCVINVTTRTSRRIQCKIPPR
GLEG-SVVTVTVFTLGHSAVLPGAFAYDSSLNPVIVSLSGNSSSVA--GGEALFIGLKL-
-LGNYADLAVEVHVWDTSVQVHAWTAQGLWVVLPPLPAGLHALSLLTFASH---------
--------------VCVLGGTILNISGEGFSRDPTLVWVLVGNQSCDIVDLTDVSISCET
PPALLSSA-ADS----LPVPVEVWVGNASFVHGLVPGLVGKGFTFTYASAATPVVAALWE
EVTNSSLKFYLEGKHLSGSVILLGGLKCDLEMLSF------------GDNMSLSGCAFPL
HSLEAGVYPVQVRHKHMGLADLSAVPQHWAMMLQVATSSPKHSPACGGTALTVLGT-RLQ
PRRKPVQADLS--APFTRVLLSLRGDTVVCQANLVGDHLAG-----ASFTV----NITVL
VSGLASSCQGNCTVFMQGRTSPVMDNVTAEINGSLVAILMVVRRLGSAAGGPLGSVEVHL
LCDLTPFNAS-HVACQLSALTPGLLYLLVVHTSDGCVCRGDVSKRLPTRPRVFRYSPRSF
SMHGGGLLAVEGAALRGQNTTSVHVGRQACLTVNV-SLELIQCVVPAGNGSVALEIEVD G
ILYHVGVIDYSEAFTPELISVSQSGG-ILTFAVARISGAANMDIFIGMVPCAGVAG----
NSTVVQCTVPPLPAGEHHVRGYDHSRGWASSALVLTVRATVTAVTENFG-YVDGGLVQVF
GAGFSLGAISAAVCGTPCRVLANATVSAFSCLVLPLDVSLAFLCGLRPEGDSCEASASTY
VQCDLTITLGTQTLAASWPYLYICDDRARGVSTPDQGAE---PGSPS-FSGLFLSPKVER
DEVLIYNSSCTITMETEAEMECETPNQPITTKITEIRKSWGQNTQGELSLQLCLRWSRAS
S WFPGRQPHDGDSVTVEKGQGLLLDVNTSTL-NMLHVKGGKVIFMGPGPVELRAHSILVS
DGGELRIGLRDKPFQGKAQITLYGSCHSTPFFPYGVKFLAVRNGTLSLHGSLPKVTVTH L
RSPAQAGDTVLALEDAVDWLPGDEAVIVSGARAEGTGLREEMVVMDTVHHRDLRLRSPLR
YSHSSTEDWLVGGHQIFKATVVLLSRSITIKGNLTQERKKFLDSCQET----SHLQCCVY
SRSEAVLGARDLGARLIIQSFAEEPSQIQLKGVQLCDLGQAFRKHLSAITVVGA--LRGS
YMQGCTVWNSF-SR GLELRGAWGLELDSNVFYKVSGHALLVGKF----------------
-TKKQ--GWPGQGNIIRSNMIISVSGAEGLSSPEMLTPAGMYIRSPTNVIEGNRVFVAGY
GYFFHLVTSETSEAPLLSFTQNTACSCTRFGLFVYPKFQPPWDHDTGLTLFQNFTVWGSA
GGARI-FRSSNLRLKNF QVYSCRDFGIDIVESDANTSLTDSLLLGRLPHE-V-GPLCMSA
GVRTPKRWELMISNTEFVNFDLMDCVAIRTCSGCSRGQGGFTVKTNNL--KFTNSPNLVA
FPFPHAAILEDLDGSLSGKNRSHVLASMATLPDSCSVNASFSQVAQGSVCGEGILFHRMS
IGL--APDVPCDLTITDSRNETTTVNYVHDTLSNRYGWMALLPGRETHALRFA-DPRLN-
RRLQYAATFDNFSPGNYLLLVHAG-LPAYP---RVLVRCGSRAGRALLSLPSPGQDQGCD
WFFNSQSRQLTYLVAGEEQVHVFLLVEEA--------STSAPASALKWSLPETWQGVEEG
WGG--HSRTIPGPGEDVLILPNKTVLVDTDLPVLKGLYVLGTLEFPVDRSNVLSVACLVI
AGGELKA--GTLENPLEKEQKLLIVLRASEGIFCDRLSGIRISPGTIGVYGKFQLHSAYP
KKPWTHL AADIAPGNDRIIVEDAVDWKPLEKIVLTSSSYEPHEAEVLPVREVKGHQIGVR
GRLQHRHIGSPHVLEDGRHIRLAAEVGLLTRNIQIQSDTSCGGTLLVGSFRKSPAEEFSG
VLQFLN---VEICNFGSPLYSSIEFTNVSLG AWILSSTLHHSCGGGIRAAASRGIVFRDN
LVFSTAGHGVDLEGEAYSLTNNLVVLTTQSAGSTAWVAGIKVIRAKDVLLRGNVVAGSER
LGFHIHGCTCSS-EMLWSSNVAHSSLHGLHLYKSSGADNCTSVSGFLAFKNFDYGAMVQA
ENHVELENITLVDNSVGLWAVVYVSSAPQHSIRNAQIVIRNSVVVATSSSFDCILDRRKP
RSANLTSMGRAPPNPKGGRVGILWPAFTSVQSQWPQDPWHKV-RNGHLVSGIIKLQ-DVT
FSGFVKSCYSNDLDICILPNAGSAGMAPPVIAERTRMLQMRAASKFYFPS----RKDLER
GTCSASDCENPRKYLFKDLDGTALGLPAPVSVFPKTEAEWTGSFFN--TGEQRSCEPGLL
-----G---------------LRPPWSSA--------------------LRCLCPGTSTC
IFFYIILWITASEPTCLFPED---------------------------------------
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--------------------------------MVTFPVSLAFLCDLRHAEDSCEVGSHTY
LQCDLTVAMGTKRLPGSWPYLYLCEESSQCLLAPDHWTE---PAFPS-FSGLFLSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPIIAKITKIQKSRGQNTQGSFPFQFCRRWSRPH
SWFPQRVPHDGDNVTVETSQLLLLDVNTSLL-NVLHIKGGKLIFMEPGPIELRAHSILIT
HGGELHIGSEQKPFQGKAHLKLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSVPQMTVTY L
RAAARAGDTMLVLEEGVDWHPGDEAVIIGGMGIEGAGPMEEVVVVEAVHNADLHLRTPLR
HSYNFTGNWVAGKNHTLRATVALLSRNITIQGNLTLERLKLLHSCQKANAAEGNLKHCLY
SKSEKMLGARDLGARVIIQSFPEEPSFVKLQGVQFRDLGQAFHKHQSSLTLVGT--MIGS
YLQSCSVWGSF-SR GLSMHRTWGLRVDSNIFYKIAGHALLIGTYMDRMFT-----TSETI
IGGKN--DWWAQGSTIRNNVIISISGAEGLSSPEVLAPAGIYTLSPTNVIEGNRVCAVGY
GYVFHLMTRQTSQAPLLSFKLNTAHSCTRYGLLIYPKFQPTWNNDTGLTLFQDFMVWGSA
GGAQI-FRSNNLHLKNF QVYACRDCGIDILESDANTLVTDSFLLGHFTHK---GSLCMSA
GIKTPKRWELMISNTTFVNFD-LNCVAIRTCSGCSQGQGGFTVKTREL--KFENSPNLVA
FPFPHAAVLEDLDGSLSGKNGSHILPSMETLSDTCSANASFSHIAPGTICPDGVLFHRMS
IGLDKALGVPKDLIVTDSRNKTITVNYVSDTLSNYYGWMALLLDQETYLLQFP-NHWMD-
RSLQYSATFDRFASRNHLLLLHRD-LPPHP---DILIRCGSRVGQSLPSPPLPSHDRGCD
WFFNIQSRQLTYLVSGEGQVQVFLQVKEGV-PPTVSASTSVPDSALKWSLPETWQDVTKG
WGG--YNQTIPGPGDDVLILPNRTVLVDTDLPVLRRLYVMGTLEFPADRSNVLSVACLLI
AGGELKV--GSLKNPLEKEQRFLVLLRASEEIFCDHFDGIHVDPGTIGVYGKLHLHSAYP
KKSWVH LGADFAPGNERIIVDDVVDWQPHDKIVLSSSSYEPHEAEVLTIKEVKGHHIRVC
ERLRHRHIGSAHIMEDGQHIPLAAEVGLLTRNIKIQSDSSCRGRLLVGSFRKSSREEFSG
VLQLLN---VEIQNLGSPLYSSIEFMGVSAG SWVISSTVHQSCGVGIHASASHGMVLNDN
VVFGTSGHGIDLEGQNYSLTNNLVILTMQSARSSPWVAGIKVNYAKDIILHGNVVAGSER
LGFHICGHGCSS-DVLWSDNVVHSSLHGLHLYKKHEPANCTGVSGFLAFKNFDYGAMVQT
ENSVVLQNITLVDNTIGLLAVAYVSSAPLSSIQAVQIVLRNSVIVATSSSFDCIQDRRAP
QSANWTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKL-RSGHAVSGIIKLQ-DVT
FSNFVKSCYSGDLDVCILPNEYSTGIMYPITAERTRMLRMKDKNKFYFPPSQP-SKDLEG
TICLESDWESARKYLFTDLDGRTLGLPPPVSVFPKREPEWTGSFFN--TGIFREEQKCTF
RAMIQGFFCKQTDHVVLILHNVDV----PKSYPLVSITNGFVDTFSRVKDSTLCSTPTSV
SSFYSILPTRQITKICFVEQTPPLLHIFLLGNRA-SKLILAVFYNEIQSPHVFLEKRFIP
PTPVESASSLLDESAGANYFDIMNNLLYVVLQGEEPVEIHSSASIHLAFTVTFSVLEKGW
ERTMLERLTHFLQIDPNQIKFTLEMPGNKETLEAIANSRGKRKRHCPTVTCGGA-ASRFG
QRRPLMAEMTS-YRITPTTSVETLSKVIVIEVGDLPNTGSTEFIPTFLSNRLQNLAHQVI
TAQQTGVLENILGMTVRALLV-TQSEGVTG---YRNASSLGTGNLIYTRPSVLSVLVQPS
DGEVGIDLPVQPQLVFLDEKNQRVESLGLPSEPWVISASLEGASDSMLK--GCT-QAETW
DGYVSFSRLAVLISGSDWRFVFTVISPP-GTNFTARSKTFAVLPVAHKERSTIILALSLC
SVVSWLALSCLVCCWFKKSKN--R------------------------------------
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-------MTGWLISLTSIKVLLLAVPCLNIHIEPEEGSLAGGTWITVIFDGLE---LGLL
HPANGSQLEIHLVN--VALPTLPSIPCDVSPVF--LDVPAVMCRTRSLL--PEAQEGVYS
LEVQAGGQVVGSPHPGPQDGRTFKFSRAQTPIVYKVNPPSGVPGKLIHVYGWIITGRSET
FDFDAEYIDSPLILEA---------QGDKWITPCSLVNRQTGSHYPIQEDHGLGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SVIHKD-AWLVSAKQD----LFLYQTYSEILSVFPETGS
LGGRTDITIIGDFFDNPAQVTIAGIPCDIRHV--SPRRIECTTRAP SKGARLSAPQAGNR
GLLFEVGDASEDLDLTEATPGYSWQIVPNASSPSGFWSKE GQPFRARLSGFFVAPETNNY
TFWIQADNQASLYFSWSEDLRTKV-KMASIRVGTADWFDSWEQNG---SDKTQQQKTPKL
ELLGGARYYLEAEHRGRAPSSGVRIGVQIHNTWLNP DVVSTYLREKHQIRAWAQRLPEIQ
MLTLSG-TGNFFLTWDNVSSQPIPANATAHQIQTAIEELLAVKCKLEPLSANILLWLGFE
QGL-EGSTSDGHLTSGTEPFCGRFSLHQPRHLVLTPPAVQKVYRLDQYTHLCLAYRGHEN
TTLKMTVSFTIGLQNPV-KNITCDWSL----LGTSPKCWQFTCTDLWKMCVHHASHLQLP
PANSPVLVHQIDLLPLS---PEMGMFYVDEIIIADTNLTVSQADTGTARPGGNLLELLSV
VGSPPVYSVTSWLAGCGLELPLITASAVPTEGAEE---------GSRLVQVTTQRLQRTS
PPLGGHFRIQLSN-TAIPGVPVHISASHLQKLLQTSADDFTSRYLNASDFTVTEDLKSCY
EHVWTFSWSSRVGDLPNFIK---VSNENLTGVNPAVTTRVVYDGGVFLGPIFGDMLVTAN
QHTQVVVRVNDIPAYCSGSCAFQYLEGSTPQVYSVWYALAYDM---D LLVYITGTSFSGD
YKALQVTVNKTSCNVIFSNQTNVVCQTSLLPIGLHQISMLVR PSGLAINASG-GGLFLNV
E PRLDT-VEPSRAADIGGLWATIRGSGLDNVNLVLFGSQSCVINVTTSNSRRIQCKVPSK
GEDG-PTVNVTVILGGHPVVLAMAFTYVSSLNPVIVSLSRNGSSIA--GGEILSIGMLL-
-PVNHTDLDAEVRIGDTRAWVLAQTAQGLEVVLPPLPAGLHGISVSINGVHIHAQGVDLH
IQYITQVFSIQPCCGSLVGGTILSISGRGFSRDRALLWVLVGNRSCDIVNSTETSIWCET
PPPAP-----LPLS--APVPVEVWAG SKPFPHRPSPRLVGKGFTFMYEVAATPVVTAMRG
EVTNHSLRLYVEGQNLFDSVVLLGNLSCDLQTPSP------------GSNLSPAGCTFPL
DTLEAGLYPLQVHQRQMGFADMSAVPQQCVVM PQITSIFPTRGSTCGGTVLTVRGL-ALR
SSRGSVEVDLS--GPFTCVILSLGDQTVLCRITPVGDPLPG-----TSFAL----NVTIL
VN GLPSMCQGNCTLFLCEETTPIVDDWT TNISGSLTTVLVRGQRLGITADEPVVFVDDRL
ACTVAFHNAS-HVACWISDLSPGPHYLSVFHA RYGYACSGNLSRHFHVWPQVF HYFPKNF
SLHGGSLLTLEGTALKGLNSTLVYIGQQACLTVSL-GSELIQCAVPAGNGSAALVIEVD G
LSYQMGVIGYSSAFTPELLSVSQTED-VLTFSVARISGAANVDIFIGMSPCVGVSG----
NHTLLHCLVPSLPTGEYQVRGYDRMRGWASSILMFTSRVTITAVTENFG-RLGGRLVHVF
GAGFSPGNISAAVCGTPCQVLANATVSAFSCLVLPLDVSLASLCDLRPEEEDCETASCSY
VHCDLIITVGTESLPESWPYFYICEESSRCLLARDHWTE---SILPS-FSGLFISPKVER
DEVLIYNSSCTITMETEAKMECETPNQPITAKITEIRKSRGQNTQGNFIFQFCGRWSRA H
SWFPQRPPQEGDNVTVEKGQLLLLDTNTSIL-NFLHVKGGKLIFLDLGPIELRTHSILVS
DGGELRIGSEDKPFQGKARIKLYGSSYSARFFPYGVKFLAVRNGTLSLHGSLPEVVVTHL
RAAANAHDTVLALEDAVDWHAGDEVLVISGMGAEDAKPKEEIVTVETVHSTDLQLRSPLR
YSHNSTEKWVAGEHHVLKVMLVLLSRSITIQGNLTDERVQFLASCQGASASEGDLQNCLY
SKSEKMLGSRDLGARVIVQSFPEEPSRVQLKGVQFRDLGQAFHEHVSSLMLVGA--MRGS
YVQGCTVRRSF-SRGLSMSQTSGLKVDSNVFYDISGHALLLGTSPEIRYI-----LWEVT
--SGGGKDWSEQGNIIRNNVIIRVSGAEGLSSPEVVTPSGIYIRHPTNVIEGNRVFAAGY
GYFFHLVTNQTSQAPLLSFTRNSAHSCTRSGLFVYPKFQPPWDNSAGSTLFQNFTVWGSA
GGAQI-FRSSNLHLKNFQVYACRDFGIDVLESDANTSITDSLLLGHFAHK---GNLCMSA
GIKSPRRWELRVSNTTFVNFDLTHCVAIRTCSGCSQGQGGFTVKTNQL--KFMNSPNLVA
FPSPHAAILEDLDGSLSGKNRSHILASMETLPATCVVKASFSQLVHGSVCEENVLFHRMS
IGLASALKVSQDLTITDSRNKTTTVSYVHDTLSNPYGWMALLLDQETYSLRFE-SPWTS-
SALQYSATFDNFAPGNFLLLVHTD-VWVYP---DILIKCGSHVGRSLSSLPSPGQDQGCD
WFFDSQLRQLTYLVSGEGQVKVVLQVRKGV-DPTISASISVPESVLKWSLPEAWEGVAEG
WGG--HSGASPGPGEDVLILSNRTVLVDTDLPPLRGLYVMGTLEFPVDRSNVLSVACMLI
AGGELRV--GTSENPLEKEKKLLILLRASEGVFCDRFSGIHIDPGTIGVFGKVQLHSAYP
KKSWTRLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVRGHHIRIH
ERLRHRHIGSAHVMEGGRHIRLAAEVGLLTRNIQIQGDTSCRGGLLVGSFRKSSVEEFSG
ILQLYN---VEIQNFGSPLYSSIELTDVSTGSWVISSSLHQSCGGGIHAAASQGIILNDN
VVFSTAGHGIDLEGQDYSLSKNLVVLMTQSAWSPVWVAGIKVNEAKNTRLHGNVVAGSER
LGFHIQGHRCSAPESLWSDNVAHSSLHGLHLYKGSGLDSCTGISGFLAFKNFDYGAMLQV
ENSMEIENLTLVDNTVGLFTAVYVSSAPRYYIRSLQIVLKNSVIVATSSSFDCIQDRVKP
HSAHLTSPDRAPSNPRGGRVGILWPVFTSEPNRWPQEPWHKV-RNSHLISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIVPPIMAERTSMLKIKDKNKFHFPPLQT-RKDLET
LVCSESDCESPGKYLFKDLDGRALGLPPPVSVFPKTEGEWTGSFFN--TGTFREEQKCTY
RPLINGYICKQTDPVILILDSADTTWAMQKLYPVVSVTSGFVDTFSSINASAPCSISRSV
SAFYSIVPTRRITKVCFVDQTPDVLHFFLLGNKNTSKLLLAVFYHELQSPYVFSGDRFIP
PTQVHSTSSLLNESIGSNYFSITDNLLYVVLQGEKPIEIRSSVSIHLALNVMFSVLEKGW
EIVILERLTVFLQINQDQIRFIHQMPGNEATLKAMADSRAKRKRNCPTVTCTSH-D-RVG
QRRPLMVEMSS-YRDLPT--MEMISKVMVIEIGDLPTVRNAGLIPSLSSNKLQNLAHQVI
IAQQTGLLESVLNMTIGALLV-TQSKGIIG---YGNTSSFKTGNLIYVRPYGLSVFVQPS
DGEVGKELTVQPQLVFLDKQNRRVESLGPPSEPWVISVSLEGTLDSVLR--GCT-HAETQ
DGYVSFSNLAVLISGSNWHFIFTVTSP-PGVNFTARSRSFAVLPVTPSERSTIIMAASLC
SGVSWLALCCLVCCWFKKSKT--RKIKNEEISETQTSDQRN----H-SHVSPKH------
QGSRVE-TEKEVTMMAEDLRMKVMLA-KL-NQLPHQ-SLNGVSRRKVSHRVVREEG----
-GSREEAAVPAPSITSVTSPRN-TCTPGSPAQQVYLQESGGWKGAQEQVLRYQLAG--QD
QLLL-LCPDLRRERQRLQ-GQSQLGKGHISLGLSQKKPGSCGATEAFCLHSVHPEAVQEQ
L-------------------------

-------MTAWLISLMSIEVLLLAVPHLSLHIEPEEGSLGGGTWITVIFDGLE---LGVL
YPNNGSQLEIHLVNVNMVVPALRSIPCDVFPVF--LDLPVVTCRTRSVL--SEAHEGLYS
LEAYFGGQLVSSPNPGPRDRCTFKFSKAQTPIVHQVYPPSGVPGKLIHIYGWIITGRLES
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNKQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFHSSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKDARLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNG---DEGTWQQKSPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
GGP-EVANSDGDLTSGMEPFCGRFSLCQPRHLVLTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTVGFQNMV-KNTTCDWTL----KRTSPESWQFHCTDLWETCVRRSGDLQPP
PANSPVLVHQIDLLPLA---QETGLFYLDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGMEPPLITARSVPTEGTEE---------GAGLVLVTAQRRQRTS
PPLGGHFRIQLPN-TVISDVPVQISAHHLHQLLQNNANDFTSRYLNASDFTVKEDLYTCY
EHLWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDI---NLTIYITGTGFSGD
SQFLQVTVNKTNCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDM-VEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVTTSNSSRIQCKVPPR
GEDG-HIVNVTVIRGDHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAS-
-LVNYTDLDVEVHVQDALAPVHTQSAWGLEVALPPLPAGRHRISVSINGVSIRSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNITEASIWCET
LPAPQIPY-AGAPT--VPAAVEVWAGNRSFAHGPSPSLVGKGFTFMYQAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSIILLGNLNCDVETQSF------------QGNTSLSGCSIPL
HSLEAGIYPLQVRQKRMGFANMSAVPQQFAVMPRIMAIFPSQGSACGGTILTVRGV-LLN
SRRRSVRVDLS--GPFTCGILSLEDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGLTSE CQGNCTLFIREEAS PVVDALSTNTSGCLTTVLIRGQRLATTGDEPMVFVDDQL
PCNVTFFNAS-HVVCQTRDLAAGPHYLSVFYTRNGYACST NVSRLFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLTVNI-GAELIRCIVPTGNGSVALEIEVDG
LWYHIGVISYNNAF TPELISVSQSDD-LLTFAVAQISGAANIDIFIGMSPCMGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFG-CLGGSLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDASLAFLCGLKHEEDSCEAARNTY
VQCDLTVAVGTEQLLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNF-LQFCRRWSRTH
S WFPERLPQDGDNITVESGQSLLLDANTSIL-NLLHIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDAVLALEDAVDWHPGDEVVIISGTGVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHIFKATVALLSRRITIQGTLTNEREKLLVSCQEANAPEGNLQHCLY
SMSEKTLGSRDMGARVIVQSFPEEPSQVQLKGVQFRVLGQAFHKRLSSLTLVGA--MRES
FIQGCTVRSSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKD--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYILSPTNVIEGNRVCGAGY
GYFFHLMTNKTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWESA
GGAQI-FRSSNLRLKNF QVYSCRDFGIDVLESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGEGVLFRRMS
IGLANTPEVSYDLTMTDSRNKTTTVNYVRDTLSNPHGWMALLLDQETYSLQSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGQVQVILRVKEGV-PPTISASTSASESAFKWSLPETWQGVEEG
WGG--YNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVV
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRMSGIHVDPGTIGVYGKVQLCSAYP
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIY
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSIEFSN VSAGSWIISSTLHQSCGGGIHAAASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGHKCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSVIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-KNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGILHPITAERTRMLKIKDKNKFYFSPLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
RFLMQGFICKQTDQVVLILDSADAIWAIQKLYPVVSVTSGFVDVFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVIVERLTNFLQIGQNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVG
QRRPLMMEMNS-YRASPPTTVETISKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENVLNMTIGALLV-TQSKGVTG---YGNTSSFKTGNLIYIRPYALSIVVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSKPFAVLPVTRKEKSTIILAACLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNQNN----H-IHISSKR------
RESQ-G-PKKEDTAVGEDVRMKVMLG-RV-NQYPHQ-LMNGVSRRKVSR-----HI----
-VQEEEAAVPAPGTSGITSHGH-ICAPGAPAQQVYLQETGNWKEGQEQLLRYQVAG--QD
QLLL-LCPDFRQERQQLP-GQSQLSKQSGSLGLSQEKKASCGATEAFCLHSVHPETIQEQ
L-------------------------

-------MTAWLISLMSIEVLLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---LGVL
YPNNGSQLEIHLVNVNMVVPALRSIPCDVFPVF--LDLPVVTCRTRSVL--SEAHEGLYF
LEAYFGGQLVSSPNPGPRDSCTFKFSKVQTPIVHHVYPPSGVPGKRIHVYGWIITGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLINRQTGRCYPIQEDHGLGTLQCRV
EGDY-IGSQNVSFSVFNKGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDSSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKDVRLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSQEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVQAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTNIEELLAVKCKLEPLWANILLRLGFE
QGP-EVSNSDGDLTSGTEPFCGRFSLCQPRHLVLTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWSL----TRTSPESWQFHCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLLPLA---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLVTTQRRQWTS
PPLGGHFRIQLPN-TVISDVPVQISAHHLHQLLQNNANDFTSRYLNASDFTVKEDLYTCY
EHVWTLSWSAQIGDLPNFIR---VSDGNLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDI---NLMIYITGTGFSGD
SQFLQVTVNKTNCKVIFSNQTNVVCQTDLLPVGMHRILMLV RPSGLAISATG-EDLFLNV
E PRLDM-VEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-HIVNVTVIRGDHFAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAR-
-LVNYTDMDVEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIRSQGVD LH
IQYLTEVF SIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEVSIWCET
LPAPQIPH-AD TPT--VPAAVEVWAGNRSFAHGPSPSLVGKGFTFMYEAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSVILLGNLNCDVETQSF------------QGNASLSGCSIPL
HSLEAGIYPLQVCQKQMGFANMSVVPQQFAVM PRIMAIFPSQGSACGGTILTVRGL-LLN
SRRRSVRVDLS--GPFTCVILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGLT SECQGNCALFIREEAS PVMDALSTNTSGSLTTVLIRGQRLATTADEPMVFVDDQL
PCNVTFFNAS-HVVCQTRDLAPGPHYLSVFYT RNGYACSGNVSRHFYIMPQVF HYFPKNF
SMHGGSLLTIEGTGLRGQNTTSVYIDQQACLTVSI-GAELIRCIVPTGNGSVALEIEVD G
LWRHIGVIGYNNAFTPELISISQSDD-ILTFAVAQISGAANIDIFIGTSPCMGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKDEEDSCEAARHTY
VQCDLTVAVGMEQLLESWPYLYICEESSQCLFVPDHWAE---SMSPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRT H
SWFPERLPQDGDNVTVENGQLLLLDTNTSIL-NLLHIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTSL
RATAHAQDTVLALEDAVDWHPGDEVVIISGTGVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEQHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLY
SMSEKILGSRDMGARVIVQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRNSF-SRGLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKD--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLMTNKTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWESA
GGAQI-FRSSNLRLKNFQVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSPSCLVNASFGRVVHGSACGRGVLFHRMS
IGLAHTPEVYYDLTMTDSRNKTTTVNYVCDTLSNPHGWMALLVDQETYSLQSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGQVQVILRVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVQLYSAYP
KNSWTHLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIY
EQLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSGEEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDN
IVFGTTGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGHKCSSCELLWSDNVAHSNLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSVIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRVGILWPVFTSEPNQWPQEPWHKV-RNDRSISGIMKFQ-DVT
FSSFVKSCYNNDLDVCILPNAENSGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCVSPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
RFLMQGFICKQTDQVVLILDSTDAIWAIQKLYPVVSVTSGFVDVFSSVNANIPCSTSGSV
STFYSILPTRQISKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGRNQIRFIHEMPGHEETLKAIADNRAKRKRNCPTVTCTSH-YRRVG
QRRPLMMEMNS-YRASPPTTVETISKVIVIEIGDSPTVRSTGTISSLSSNKLQNLAHQVI
TAQQTGVLENVLNMTIGALLV-TQSKGVIG---YGNTSSFKTGNLIYIRPYALSILVQPS
DGEVGNELPVQPQLVFLDGQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSKPFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNQNN----H-IHISSKR------
RESQ-G-PKKEDTVVGEDMRMRVMLG-KV-NQSPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHGH-ICAPGAPAQQMYLQETGNWKEGQEQLLRYQLAG--QD
QLLL-LCPDFRQERQQLP-GQSRLSKQSGSLGLSQEKKASCGATEAFCLHSVHPETIQEQ
L-------------------------

MSHLVCKMIACLYSLMTIEMILLAASCRNWHIVPDEGSVAGGTWITIVFDGLE---QSFL
YPTSGSQLEISLVNV--DLPWLPHVPCDVSPVY--EDVALLRCQTRSLQW--ETQEGLYY
LEVRSGGQLFSSMSKGSWDNCTFKFSKAQTPIVYQVNPPSGVPGNLIQVHGWIITGRTET
FDNDVEYIDSPLTLQA---------QGGEWITPCSLVDREKGNRYPVEEDHGIGVLQCRV
EGHY-IGSQNVSFSVFNKGK-STVHKD-AWLISAKQE----LFLYQTYSEIWSVFPVSGS
LGGGTDITITGDFFDYSAQVTIAGIPCRIKYI--SPRKIECTTRPLKQDTKLTSPHPGNR
GLLFEVGDAQEDLDPTNTTPGYRWQIVPNASSPFGFWSEEGQHFRARLSGFFVSPETNNY
TFWIQADSPASLYFSQSADPENKM-KVAFIQAGATDWFNSWERNG---HLEAWQQKSQKL
ELLGGAKYYLEANHYGVTPSHGMSIGVQIHNTWLNPDVVNSYHREKLQIRARAQRIPEIQ
ILNVTG-TGTFCLTWDGVSSQPVTTNATAAEIQAAIEELLTVKCKLEPLSAQILLWFGFE
KGL-EDSGPDGDLTSGTEPFCGRFSIHQPQFLVRTSEAMQMRYQLDQYTHLCFAYKGHMN
DTMTLSVSFTNKFHKPVKKKIVCEWNP----EQLTPESWKFVCNELWETCVRHSGGLYTR
LANSPVLVHRIDMSPLE---HEKSHFYIDEIIVADRNLTVSQVHSRIARPGGKLIESLSV
TGAPSTYNITLWMAGCGCELPLIQPCYLPPEEANE---------SSRRVSVTVQRLQRMS
PALEGHFRIQLPN-TVISGIPVHISAHDLLELLQNSGDDFASQFLNVSDFKVQKDLSSCY
EHVWTLMWMSQIGDLPNIIR---VSAENLTGIIPTVSTRVVYDGGIFLGPIFGDMLVTPN
TYPQVTMRVNDIPAHCSGSCSFQYLQESTPLVQAVWYSYDDDI---NLLVCIMGSGFPGD
SGALKIKVNQQICEITFSNQTYVTCKMGFLPIGKYQVVMLVR HLGFALNVTGGEGIHFNI
EPKLKI-MEPSVAPEIGGLWTTIQGTNLEHVSLVLFGSQPCPVNITTRKIERIQCKVPPW
GNSSRILVNVTIITRNVSVSYPEAFKYSPSLNPVILSLSRIRSNTA--GDQTLFIGTTS-
-LANYTDLNVEVHIQDTLATILKQVPQGLEVALPSLPAGWHNISVTMNGVNIIAEGVDLQ
IQYITEVFKIEPCCGSLLGGTTLTISGIGFSKDPSLVTVSVGNQTCNIVNSTEETIWCET
SAAPHLPG-TESQ--AVMVPIEVLVG NIRAHHGPSFGLGK-DFTFIYHTALTPFVTAMQG
QIRGDMLEFQVEGNNLSESVVLLGHMKCDLELQFF------------SFNRTQYFCSLPL
ANMEAGIYPIQVFRKDIGFANISAVPHSFTVA PQITDIFPTHGSVCGGTWLTVIGL-AFK
SRMKLVQIDLS--DHHTCAIWKWNDQMILCQVSFVG-HLPK-----ASLAM----NVTIT
ANGISSECQGNCTFYLQEESTPIVETLTTSVSGTLTTMLIGGQKLATATDELVVLVDDHL
SCDITFYNAT-WVECQLSDLGPGLHHFSLLNGRSGFACLGTLAPHFSIVPQVLGYHPQNF
SINGGGLLTIEGTTLRGKNTTSVLIGHQPCFTVNI-SSVLIQCIVPPGNGTVDLEIEVDG
NLIDVGIISYSEV FTPALLFILQIDGLIVTFMVARTSGAKNMQIFIGASPCVGILG----
NYTVLQCSVAQLPTGEYQVKGFDRFRGWASSTLVFTSNVTITSIHRNFG-CLSGSLLHVH
GSGFSPGNMSAEVCGVPCQVLDNATVTNFSCLVLPLDASLAFLCNLRPLEESCKATKTTY
IQCELTVTVGTINLLRSWSYIYMCEENPWCSLVLDHQVD---SSLGL-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECEAPNQPITAKITEIRKNWGQNTQDYFQLQVCRRWSRA H
SWIPQGWPQDGDNVTVESGQTLLLDITTSVL-SMLHIKGGKLIFTGPGPIELHAHCILVS
HGGELQIGSLDEPYHGKALIYLHGSS-STTFYPYGAKFLAVRNGTLSLHGLRPEVSITHL
RTAAQANDTMLALEDHVDWHPGEEV-IISGVTLEGSQRQEEIAIIESTHGANLHLQSPLR
YSHGILEHNIGGHHIALRVTVALLSRNIAIQGHLTNEGMAHLQLCTEAKIPEDDFQQCLY
LRSEKNLGSMNLGAVVIVQSLPGEPSQVQLQGVQFQYMGQAFQKHLCALNVIGP--IRDS
YIRSCSVWDSF-SRGLSLSRTSNLIVENNVFYNILGHGLLVGTHMEMKHF-----PWKAV
PRRKT--DWSRQGNIVRSNVVIGVFGTEGLSNIEVLSPAGIYIQDPISVVERNMVCAAGY
GYFFHLGTSETSKAPLRSFTQNVAHSCTRYGLLVYPRFEPPQVNDTGPTLFQNFTAWGSQ
GGVQI-FRSSNLQLKNFQIYSCKDFGIDILESDANSSIVESLLLSHYSSKK--GSSCMSA
GIKTPKRQELLVSKTTFVNFDQKNCISLRTCSSCYRGQGGFTVKTEQL--KFLNSPNRIA
FPFPHAAILEDLDGSVSGNKGRYLLASVENLASSCQVNQSFGQTVKGSVCGPDVIFHRMS
IGLAEAPDVAYDLTVTDSKNQTMTINFVNDTLSNLYGWMALLLDQDTYLLRFE-ASWIK-
SSLQYSATFDNFTSGNYLLVVHKD-LQPYA---DILVICGTRIGQSLLSSPSATRDQACD
WFFNSHLGELTYLVSGEGQVHLTLLVKERI-IPATPVPSDVPKSILKWSHPGTWQGVEEG
WGG--YNHTTPAPGDDVVILPNKTILVDTDLPFLKGLYVLGTLEFPVNRSNVLNVACIIV
AGGELKV--GTFPEPLHKGQKLLIQLRASEGDYCDRLDGINIAPGTFGVYGKVQLHSAYP
RKAWTHLGADIASGNERILVKDEVDWRPQDKIVLSSSSYEPHEAEILTIKEVMGQNVRLY
EHLNHRHLGSSHSMEDGRHISLAAEVGLLTRNIKIQPDAPCGGRMVVGSFQKPNGEEFSG
TLQLSN---VEIQNFGSLLYPSIEFNNVSLGSWMISSSVHQSCGGGIRVSSSKSIFLHDN
ILFDTTGHGIDLEGQNHSLIKNLIVLTKQPQRAMDWVTGIKVNQVNDANLIGNAVAGSER
IGFHIKGHDCSMAENPWVGNVVHSSLHGLHVYKGDGLYNCTKISGFLSYKNFDYGAMFHV
ENNLEINNMTLVDNVVGLLPLVYASFPEQCSLEKKQIVLRNSIIVATSSSFDCIEDRIKP
LSADFTSRDRPPSNPRGGRVGILWPGFTAEPNQWPQDAWHKV-KNYPSVSGIMRLE-GVT
FSDFVKSCYSNDLDVCILPNPDSPGIIPPIMAERTKMLKVKDQNKFYFSLPWL-RKETGK
IVCPELDCESPMKYLFKDLDGSVLDLPPPISVFPKSKSEWVGSCFN--TGIFREDRKCTY
RPSMQSFVCKQMDYILLILDNITIAPGKKIPSSVVSVTSGFVETFSSIVAHSSCSASLSI
PAFYSLLPTNSLTKICFVNGVPQAMRFYLIGSERSSKV-LAVFYPELQSPRVFFRGQFIP
PTSVLSDSWQENGATGTNHFSFMDNLLYILLQGDEPVEVQSAISIYVAFTVTLSSALEDW
EPAIDQRLAHFLQIGQDHIRIVHILPGGERILKAFADGVAKRKHHCPSGTPCTN-CHRLG
QHRNFMRKMKM--WVPPSTFSETISKVVVIEIGDLSGIGNAKVASSLSTDGLQCLVHRII
TSQQTGELQEALNMPVEALLI-SQSAGVFT---SGNSSSLDTGSVVYIQPFTLSVQVQPS
SGEVGIELPVQPHLVFLDKQGRVVESLGPPSEPWIVTVSLEGASETVLK--GHT-HAEAH
QGRVSFSNLAVSSSGSNWYFLFTVTSPP-GAKFNVRSEPFAVLPVNKGEKSTILMALVLC
SAASWMALCFLVFCWLKKSKK--TKTKETSGPQVADRKKN-----P-QVKHNSHPTRN--
QERLEE-TKKGTTVIQEDMRQKAIQG-KP-NQSSYQQSLNGLTRRMIRTG-------HRE
GGR---GEVPTEVIAHLPSQGHDDLSSGTPAQQVPIQEVRDWKDGQAHLLGYHPTE--QD
QLLV-LYPSFDQEGQKLP-EQRHADRKSDHLGYYWDRKA---KSESFHLHSLQQAPLQGQ
L-------------------------

-------MTTWLISLISIETLLLAVPYLSFHIEPEEGSLAGGTWITVIFDGR----LGLL
YPANGSQLEIHLMS--AAVPALPSIPCDVVPVF--LDLPVVMCRTRSLP--SEAHEGLYY
LEAHSQGQVASSSTPGPQDSPTFKFSRAQTPFVYQVNPPSGVPGELIQVYGWIITRRSET
FDFDAEYIDSPLILEA---------QGDRWVTPCSLVNRQTGSRYPVQEHHGLGTLQCRV
EGHY-IGSQNVSFSVFNKGK-SMVHKN-AWLISANQD----LFLYQTYSEILSVVPETGS
LGGRTDITITGAFFDNPAQVTIAGIPCDIRHV--SPRKIACTTRAPGKGTRLTAPQAGNR
GLLFEVGDAAEGLDLTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQATLYFSQSEDPRTKV-KVASIRVGTADWFDSWEQKG---NEGTWQQKTPKL
ELFGGARYYLEAEHHGRAPSRGMRIGVQIHNTWLNPDVVSTYLQEKHQIRIRAQRLPEIQ
MLTVSG-RGNFLLTWDNVSSQPIPANATAHQIQTALEELLAVKCKLEPLSANILFRLGFE
EGP-EGSSSDGDLTSGTEPFCGRFSLYQPRHLVLTPPAAQKGYRLDQYTHLCMAYKGHMN
TILKVTVSFTVDFQNVA-KNITCDWRL----EGTSPNSWQFTCTDLWNTCVHRSTDLQPP
LASSPALVHLIDLLPLS---QEPGVFYMDEIVIADTNLTVSQADSGTARPGGNLVELLSV
VGSPPVYNVTCWLAGCGPELPLISASSVPTEGAEE---------RSGLVHVTTQRLQRTS
LPLGGHFRIQLSN-TVIPDVPVHISASHLHKLLRNNADDFTARYLNVSDFSVMEDLKSCY
ERVWTLSWSAQVGDLPNFIR---VSDENLTGVNPVATTRVVYDGGVFLGPIFGDMLVTAN
RCPQVVVRVNDIPAHCSGSCSFRYLEASTPRVHSVCYSPDGDT---DLLVYITGTSFSGD
YKALQVTVNKTSCKVIFSNQTNVVCQADLLPVGVHQISMLVR PSGRAINASG-GGLFLNV
E PRLDA-VEPSRAAEIGGLWATIRGSSLEDVSLVLFGSQSCVINVTTSNSRRIQCKVPPR
GKDG-HVVNVTVIREDHSTVLPMAFT YDSSLN PVITSLSRNRSSIA--GGETLFIGMAL-
-LVNDTDLDVQVHIQETLAPVHEQMAQGLEVVLPLLPAGLHRISVSINGVNISSQGVD LH
IHCITEVF SIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNQSCDIVNSTERNIWCET
SPASLLPD-ADDL S--VPAPVEVWAGSTSISRAPSPSLVGKGFIFMYEVAATPVVTAVRG
EITDSSLRLDVEGSNLSNSVILLGGLACGLETQSF------------RSNVSLSGCSFPL
HSLEAGIYPLQVRQKQMGFANMSAVPQQFVVT PRITAIFPAHGSACGGTVLTVQGL-ALS
SRRGSVQVDLS--GPFTCVILSLGDQTVLCQIHLVGDPLPG-----ASFTL----NVTVL
VN ELPSECQGDCTLFLREETT PVVDALTTNISGSLTTVLIRGQRLGTTADEPVVSVDDHL
LCNVTFFNAS-HVTCWISGLTPGPHYLSVFHR RNGYACSGNVSRHFDIL PQVFRYFPKNF
SIHGGGLLTVEGTALRGQNATLVYVGWQACLTVNV-SSDLIQCIVPSGNGSVALNIEVDR
LSHQMGVISYSNT FTPELLSLSQTDD-VLTFAVAQISGAMNVDILIGMSPCMNVSG----
NRTVLQCVVPSLPAGEYQVRGYDRTRGWASSALVFTSRVSVTAVTQNFG-CLGGRLVHVS
GAGFPPENISAAVCGAPCQVLANATVSAFSCLVLPLDVSLAFLCGLKHEEEGCDASSRTY
VQCDLTVTVGTESLLSSWPYFYICEESPSCLFAPGHWTE---SASPW-FSGLFISPKVER
DEVLIYNSSCNITMETEAKMECETPNQPITAKITEIRESRAQNTQGNFSFQFCRRWSRA H
SWFPERVPQDGDNVTVEKGQLLLLDTNTSIL-NLLHVKGGKLIFMDPGPIELRAHSILVS
HGGELRIGSKDKPFQGKAEIKLYGSSHSTPFFPYGVKFLAVRNGTLSLHGLLPEVMVTHL
RAAAYARDTVLALEDAVDWHPGDEVVIISGIGVAGAKPMEEIVIVETVHNADLHLRSPLR
YSHNFTENWVAGEHHILKVMVVLLSRNITIRGNLTNERMKLLASCQEASASEGNLQNCLY
SKSEKMLGSRDLGARLIVQSLPGEPSRVQLKGVLFRELGQAFRKHLSSLTLVGA--MRDS
YLQGCTVWGSF-SRGLSMSRTLGLKVTSNVFYNILGHALLVGTYMEVRYI-----LWEAM
PTRKN--DESEQGSIIRNNVIIRVSGAEGLSSPEVLTPSGIYIRNPTNVVEGNRVCAAGY
GYFFHLVTSRTSQAPLLSFTGNVAHSCTRYGLFVYPKFQPPWDDGTGPTLIQNFMVWGGA
GGAQI-FRSSNLLLKNFQIYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSA
GIKTPKRQELVVSNTTFVNFDLTECVAIRTCSGCSRGQGGFTVKTNQL--KFTNSPNLVA
FPFAHAAILEDLDGSLSGKNRSHILASMETLSASCWVNTSFSQVVSGSVCGEDVLFHRMS
IGLANAPDVSSDLTMTDSRNKTTTVNYVRDTLSNRYGWMALLLDQEMYSLRFE-TPWIS-
RSLQYSATFDNFAPGNYLLLVHAD-VWPYP---DILMWCGSHVGRSLPSLPSPGRDQGCD
WFFDSQLRQLTYLVSGEGQVRVILQVKEGV-PPTISASTSVPESALKWSHPEAWTGVEEG
WGG--HNHTTPGPGDDVLILPNRTVLVDTDLPFLKGLYVMGTLEFPVDRSNILSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRFDGIHIDPGTIGVYGKVQLHSAYP
KKSWTHLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHETEVLTVKEVKGHHVRLH
ERLKHRHIGNVHVMEDGRYIRLAAEVGLLTRNIQIQSDTSCKGRLRVGSFRKSSREEFSG
VLQLSN---VEIQNFGSPLYSSIELTNVSAGSWIISSTLHQSCSGGIHAVASHGIILNDN
IVFGTAGHGIDLEGQAYSLSNNLVVLMTQSAWSTVWVAGIKVNRAKDINLRGNVVAGSER
LGFHIRGHSCSSPEALWSDNVAHSSLHGLHFYQESGLDNCTGISGFLAFKNFDYGAMLHV
ENSVEMENITLVDNAVGLLAVVYVSSVPQSSIGNVQIVLRNSVIVATSSSFDCIQDRIKP
CSANSTSTDRAPSNPKGGRIGILWPAFTSEPNQWPQEPWHKV-RNGHSVSGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENVGIMHPITAERTRMLKIKDKNKFYFPPLQT-RKDLGI
LVCPELDCESPRKYLFKDLDGRALGLPPPVSVFPKIEAEWTGSFFN--TGTFREEQKCVY
RPLIQGYICKQTDQVILILDNADATWAMRKLYPVVSVTSGFVDTFSSVNANTPCSTSGSV
STFYSILPTREITKVCFVDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPQVFLGGSFIP
PTLVQSTSSLLDEPIGSNYFSIMDNLLYVVLQGEEPVEILSDASLHLVLTVMFSILEKGW
EVMFFERLTEFLQIGQDQIRFTHEMPGNEATLKAIADSRTKRKRNCPTVTCANH-Y-RAG
RRRPLMIEMSS-HRVPPPTTTEPISKVMVIEIGDLPTVKSTGPIPSLSSNKLQNLAHQII
TAQQTGLLENVLNMTIGGLMV-TQSKGVIG---YGNTSSFKTGNLIYIRPYALSVLVQPS
DGEVGKELPVQPQLVFLDKQNRRVESLGTPSEPWAVSISLEGTSDSVLK--GCT-QAEAQ
DGYVRFSNLAVLISGSNWHFIFTVISPP-GVNFTARSRPFAILPVTRSESSTIILAASLC
SVVSWLALCCLVCCWFKKSKS--RKIKSEEISESQTNDQKN----P-THVPSKR------
QGSQVE-TGKEDAVMGEDMRKKVMLG-KL-NQLPHQ-SLNGVSRRKVSRRTVGEEH----
-GSQEGAAVPAPNLTSLTSHGH-TCAPGSPARQVCVQETGNWKKAQEQLLRYQLAG--QD
QLLL-LCPDLRQERQRMQ-GQSQLGKEGGRLGLSQEKKTSCGATESFCLHSVRPETIQEQ
L-------------------------

-------MTGWLIPLMTVEVLILSVPHPSLHVELEEGSLAGGTWITVTFDGLD---SRIL
YPTNGSQLEISLVNV--AVSALPSVPCDISPLF--LDLPVVMCQTRSVL--NEAHEGLYS
LEVRSGGRVVGSPGLGPQDSCTFKFSKAQTPIIYQVNPPSGVPGKLIHVYGWIITGRLET
FDVDAEYIDSPLVLEA---------QGEKWVTPCSLINRQTGSHYPLQEDHGLGTLTCRV
EGNY-IGSQNISFSVFNKGK-SMVNKS-AWLISAKQD----LFLYQTHSEILSVFPESGS
LGGRTDITITGDFFDNSAQVTIAGIPCDTSHV--SPRKIECTTRAPGRGTRLTAPQAGNR
GLLFEVGDVAEGLELTEATPGYRRQIVPNASSSFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASIRIGTTDWFDSWEQNG---NEGTWQQKTPKM
ELVGGAKYYLEAEHHGITPSRGMRIGVQIHNTWLNPDVVTTYLREKHQISVRAQRLPEIQ
VLNVSG-RGDFFLTWDNVSSQPIPANATAQQIQTTIENLLAVKCNLEPLSANILLRLGFE
QGL-EGSSSDGDLTSGTEPFCGRFSLHQPRHLDLIPRAAQKGYRLDQYSHLCMAYKGYRN
TILRMTVSFVIGFQNITKKNSTCDWSL----MGTSPKSWQFTCTDLWDVCVHRSGDLQLL
QANAPVLVHQIALHSPA---QGMGFLYVDEIIIADTNLTVSQDDSSTARPGGNLVESVSV
LGSHPVYSVASWVTGCGTELPLITSRSVPTEGM-E---------DSELVQGTTQRLQKTS
PPLGGHFRIQLSN-TVIPDVPVHISAGHLHKLLQDNADDFTSRYLNVSDFTVKEDVNSCY
EHVWTLSWSTQVGDLPNFIK---VSDQSLRGMNPSVAIRVVFDGGVFLGPIFGDMLAAAH
QHAQVVVRVNDIPAQCLGSCSFQYLSGSTPRVHSVWCSLDGDT---NPLVYITGTGFSGD
SQSLQVTVNETSCKVIFSNQTTVVCQTDPLPVGVHQVSVLVK PSGLAVNASG-DDLLLYV
E PRLDA-VEPSQAAEIGGLWATIRGCSLEDVSLVLFGSQSCAINVTTRNSRRIQCKVPPR
GKDG-YLVNVT VFSREHSAVLPRSFAYIASLN PVIVSLSRNRSNIA--GGETLFIGMAL-
-LENYTDLDVEIHVQHTLVQVHSQTAQGLQVVLPPLPAGLHRLSVSINGISICSQG VVLH
IWYVTEVF SIEPCCGSLLGGTILSISGVGFSRNPTLVWVLVGNQPCDIVDLKEMSIRCET
LPTPLLSG-ADS----FPVPVEVWAG NTSFIHSPALSSVGKGFTFTYESAATPVVSAMWE
EITNSSLRFLVEGNNLSNSVILLGSWKCDLETQSF------------VGSVSLSGCAFPL
HSLEAGIYPLQVRHKHLGFANMSAVPQHFAVK PLVTSISPTHSSACGGTVLTVRGM-TFK
SRRKSLCVDLS--GPFTCVILSLSDDTVICQVNLVGDPLAG-----ASFTL----NVTVL
VNGLASACRGDCTVFMKEETTPAVDTLTVGISGSLVTVLMRGQRLGSNTDEPVVFVDNHL
RCDLTFFNAS-HVACHINGLTPGLHFLSAVQTNNGFACWGNVSRHFSIKPQVFHYYPKNF
SIHGGSILAIEGTALRGQNTTSVYVGQQACLTINI-SSELIQCIVPEGNGSVSLEIEV DR
ILYHIGVIDYSDAFTPELISISQSDD-ILTFAVAQISGAANMDIFIGISPCAGVSG----
NHTVVQCTVPFFPAGEYHVRGYDHSRGWASSALVFTVRVTITAVTENFG-CLGGRLVHVF
GAGFSPGTVSATVCGTPCQVLANATVSAFSCLVLPLDVSLAFLCGLKPEEDSCEAIVRTY
VQCDLTVTVGTQRLAESWPYLYICEESSPCVLTSDQWTE---SAFPS-FSGLFISPKVER
DEVLIYNSSCAITMETEAEMECEPPNQPITTKITEIRKSWGQNTQGNFSLKFCLRWSRTH
S WFPNRQPQDGDNVTVEKGQLLLLDTNTSIL-NLLHVKGGKLVFMGPGPIELKAHAILVS
DGGELRIGSEDKPFQGKAQIKLYGNSHSSPFFPYGVKFLAVRNGTLSLHGSLPAVTVTH L
RAASRAEDTVLALEDAVDWRPGDKVVIVSGTGVEGASLLEEIVTVETTHHADLHLRSPLR
YSHNWTENWVAGEQRILKATVALLSRSITIKGNLTHERRKFLASCQESSVPEGNLQHCLY
SKSEKVLGSRDLGARIIIQSFPKEPSRVQLKGVQFRHMGQAFQKHLSSITLVGA--MRGS
YIRGCTVWSSF-SRGLDLG RTWGLEVDSNVIYKILGHALLVGTFKEISSI-----PWEFI
PGRKH--GLSEQGNIVRNNVIISVSGAEGLSSPEMLAPSGIYIRSPNNVIEGNRVFAAGY
GYFFHLVTSQTSQAPLLSFTQNVAHSCTRLGLFVYPKFQPPWDHNTGPTVFQNFMVWGSA
GGAQI-FRSRNLHLKNF QVYSCRDFGIDITESDANTSVSDSLLLGHFTHK-LQERLCMSA
GIKTPKRWELMISNTTFVNFDLINCVAIRTCSGCSQGQGGFTVKTNHL--KFTNSPNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMEILSASCSVNASYSQIVSGSVCGEGVLFHRMS
VALPHAPDVPCDLIITDRRNKTTTVNYVQDTLSNHYGWMALLLDQMTYSLRFA-DPCVN-
RSLQYSATFDNFSSGNYLLLVHTN-LPPYP---HILLRCGSRVGWSLLSLPSPGQDQGCD
WFFDSQSGQLTYLVSGEDQVQVTLQVKEGVVPATISAFTSVPKSTLKWSFPETWKDVEEG
WGG--YNHTIPGPGDDVLILPNKTVLVDTDLPFLKGLYVMGTLEFPVDRSNVLSVACLVI
AGGELRA--GTVENPLEKGQKLRILLRASEGIFCNRFNGIHIDPGAIGVYGKFQLHSAYP
EKSWTR LGADISPGNERIIVEDAVDWKPLDKIVLSSSSYEPHEAEVLTVKEVKGHHIQVH
ERLQHRHIGSPHVMADGRHIHLAAEVGLLTRHIQIQLDTSCSGTLLVGSFRKSPREEFSG
VLQFLN---VEIQNFGSPLYSSIEFT NVSSGSWILSSTLHQNCGGGIHASASYEIILNEN
IVFGTAGHGIDLEGEAYSLTNNLVVLMTQAVWSTTWVAGIKVNQAKDILLHGNVVAGSER
LGFHIQGQRCSS-KVFWSDNVAHSNLHGLHLYKKSGPDNCTSIAGFLAFKNFDYGAMIQI
ENTVEIENITLIDNSVGLLAVVHVSSTPQHSIKNVQIVLRNSVIVATSSSFDCILDKIKP
HSANLTSADRAPPNPKGGRVGMLWPVFTTVQNQWPREPWHKI-RNHRSVSGIMKLQ-DVT
FSSFVKSCYSDDLDICILPNPESTGMVHPIIAERTRMLKMRDKNKFYFLPLHP-RQDLER
VICLEPECESPRKYLFKDLDGTALGLPPPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
QPLIQGFICKQTDQVVLTLDSVNSPWAIQKLYPVVSVTSGFVDTFSSINDNTLCSTSESV
SAFYSILPTRQITKVCFVDQTPQILRFILIGNKSTSKVLLAIFYHELQSPHVFLRGSFIP
PTLVQSTSSLLDESVGANYFSIVDNLFYVVLQGEEPIEIRTDVSLHLAFTVTFSVLEKGW
EVVLLEKVANFLQIDQNQIRFTHEMPGNERTLKAIADSKAKRKRKCPTVTCASP--RKVG
QRRPLMMEMSS-YKDSPPTTMEIASKVIVFEIGDLPAPKRTGLIPLLSSNKLQSLAHQII
TAQQTGVLENVLNVTIGALMV-TQSKGVTG---NGNTSNFKAENLIYVRPYALFVLVQPS
DGEVGKELPVQPQLVFLDKQNQRVESLGSPSEPWTISVSLEGTSKSVLR--GCT-QENTQ
DGYVRFSNLAVLISGSNWNFIFTVTSPP-GANFTARSRSFAVLPETGRERSTIILAASLC
SVVSWLALSCLVCCWFNRNK--HRKTKPEEISESQANDQKN----Q-IHVSSKH------
QASQIE-IEEEDSRKADDTRMKVLLG-RL-NQLPHQ-TLDGVSRRKLGHR----HA----
-------AVPAPSTASLTSQGH-TSAPGSPARQVHLPETRNWKETQEQLLRYQLAH--PD
QLLL-LGPDLSQDRQQWQ-GQL--SEERGNLGLSQEKNTS--------------------
--------------------------

-------MTAWLISLLSIEVLLLAVPHQNLHIEPEEGSLAGGTWITVIFDGLE---SSVL
YPNNGSQLEIHLVNMNVVVPPLPSIPCDVFPVF--LDFPVVTCRTRSLL--SEAHEGLYS
LEAYFGGQLISSPRPGLQDRCTFKFSKAQTPIVHQVYPSSGVPGKLIHVYGWIITGRLET
FDFDAEYIDSPVILEA---------EGDKWVTPCSLVNRQTGSCYPVQEDHGFGTLQCHV
EGDY-IGSQNISFSVFNRGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDSSAQVTIAGIPCDIRHV--SSRKIECTTWAPGKNARLTSPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISIGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGIKYYLEAEHHGIAPSTGMRIGVQIHNTWLNPDVVTTYLQEKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLSAKILLRLGFE
RGP-EVSSSDGDLTSGTEPFCGRFSLRQPRHLVLTPLAAQKGYRLDQYTQLCLAYKGNTN
KILKMTVSFTIGFQNMV-KNTTCDWSL----MRTSPKSWQFRCTDLWETCVRCSGDLQPP
LANSPVLVHQIDLLPLA---QETGLFYVDEIIIADTNLTVSQADSGTARPGGHLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTDQ---------GSGLVLVTIQRRQQMS
PPLGGHFRIQLPT-TVISDVPVHISAHHLHQLLQNNADNFTSRYLNASDFTVKEDVNTCY
EHVWTLSWSTQTGDLPNFIR---VSDENLTGVKPVAATRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAYCSGSCSFQYLQGSTPWVHSVWYSIDGDI---NLMVYITGTGFSGD
SQFLEVTVNKTNCKVIFSNQTNVVCQTGLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDA-VEPSRAAETGGLWATIRGSSLEGVGLVLFGSYSCAINVTISNSSRIQCKVPPR
GKDG-HIVNVTVIRGDYSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGESLAIGVAL-
-LVNYTDLDVEVHIQDALAPVHMQAAWGLEVTLPPLPAGLHRISVSINGVSIRSQGVD LH
IQYITEVF SVEPCCGSLLGGTILSISGIGFSRDPTLVWVLVGDQPCNIVNLMEASIWCET
PPAPQMPH-AGT PT--VPAAVEVWAGNRSFIHGPSPSLVGNSFTFTYEAAATPLVTALQA
EITNSSLHLRVGGSNLANSVILLGRLNCDVDTQSF------------QSNASLSGCSIPL
HSLEADVYPLQVRHKQMGFANMSMVPQQFAVM PRIMAIVPSQGSACGGTILTVRGL-LLN
SRRRSVRVYLS--DPFTCVILSLGDRTILCQVSLEGDPLPG-----ASFTL----NVTVL
VNGLTSECQGNCT FFMQEEASPVMDALAT NTNGSLTTVLMRGQRLGTTADELMVFVDDQL
PCNVTFFNAS-HVACQTRDLAPGLHYLSVFYARNG YACTGNVSRHFYIMPQVF HYFPKNF
SIYGGGLLTVEGIGLRGQNTTSVYIDQQACLMVNI-SAELIQCIVPTGNGSVALEIEVD G
LLYHIGVIGYSSAFTPELLSISQRDD-ILTFAVAQISGAANIDIFVGMSPCMGVSG----
NHTVLQCVVPSLPAGEYHVRAYDYIRGWASSVQVFTSRVVITAVTENFG-CLGGRLVHVF
GVGFSPGNVSAAVCGAPCRVLANATVSAFSCLVPPLDVSLTFLCGVKHEEDNCEAARHTY
VQCDLTVAMGTEGLLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFPLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSIL-NLLHVKGGKLIFLAPGPIELRAHAILVS
DGGELRVGSKNKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPKVIVTH L
RTTAHARDTVLALEDAVDWHPGDEVVIIGGTSVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGHLQHCLY
STSEKTLGSRDMGARVIIQSFPEEPSRVLLKGVQFRVLGQAFHKHLSSLILVGV--MRES
FIQGCTVWNSF-SRG LSMCRTLGLKVDSNIFYNILGHALLVGTCMEMRYI-----SWEAI
RGRKD--DWSGHGNIIRNNIIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCAAGY
GYFFHLVTSQTSRAPLLSFAQNVAHSCTRCGLFVYPKFQPPWNNVTGTTVFQNFTVWESA
GGVQI-FRSSNLHLKNF QVYSCRDFGVDILESDANTSVTDSLLLGHFAHE---GSLCMSS
GIKTPKRWELMVSNTVFVNFDLINCVAIRTCSGCSQGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASVETLSASCLVNASFGQVVHGSACGGGVLFHRMS
IGLANAPEVSCDLTMTDSRNKTTTVNYVRDTLSNPYGWMALLLDQETYSLHFE-NLWIN-
RSLQYSATFDNFAPGNYLWLVHTD-LPPYP---DILLKCGSRVGLSFPFLPSPAQNQGCD
WFFNSQLRQLTYLVSGEGRVQVILQVKEGM-PPTISASTSAPYSALKWSFPETWQGVEEG
WGG--HNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKFQLYSAYP
KKSWTH LGADIASGNERLILEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGRYVRIH
ERLKHRHIGSVHVMEDGRRIHLAAEVGLLTRNIQIQPDVSCRGRLLVGSFRKSSREEFSG
VLQLLN---VEIQNFGSSLYSSVEFSNV STGSWIISSTLHQSCGGGIHAAASHGVLLNDN
IVFGTVGHGIDLEGQAYSLTNNLVVLMTQPTWSNIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGYKCSSCEVLWSDNVAHSSLHGLHLYKESGFDNCTRISGFLAFKNFDYGAMLHA
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKNMQIVLRNSVIVATSSSFDCLQDKVKP
HSANLTSSDRAPSNPRGGRIGILWPVFTSQPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVNSCYSDDLDVCILPNAENTGIIQPITAERTRMLKMKDKNKFYFSPLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
RFLMQGFICKQTDQVVLVLDSADVTWANRKLYPVVSVTSGFVDIFSSVNANFPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPYVFLGESFIA
PTLVQSTSLLLNESAGANYFSIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLSNFLQIGHNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCASR-YRRVS
QRRPLMMEMNS-YGVSPPTTVETISKLIVIEIGDLPTVRNNGMISSLSSNKLQNLAHQVI
TAQQTGILENVLNMPIGALLV-TQSKGVIG---YGNTSSFKTGNSIYIRPYALSVLVQPS
DGEVGNELPVQPQLVFLDKQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSKPFAILPVTRKEKSTIILAASLS
SVVSWLALSCLVCCWLKRGK--SRKMKPEEIPESQTNNQNN----H-THISSKC------
QESQ-G-TKKEDTVVGEDMRMKAMLG-RL-NQCPHQ-LMNGVSRRKVSR-----HI----
-VQEEGAALPAPATTSITSHGH-TCAPGAPARPVYLQETGNWKEAQEHLLRYQLAG--QD
QLLL-LCSDLRQERQHLP-GQSRLSKKSGNLGLSQEKKTSCGATEAFCLHSVHPGTIQEQ
L-------------------------

-------MSVWLISQTSIEILLLAVTCLSFHIEPKEGSLAGGTWITVIFDDLE---SGLL
YPINGSQLEIHLVNV--IGPALPNIPCDISPVF--LDLPLVMCRTRSLF--SEAHDGLYY
LAVRSRGQVVHSPYPGPPNSSTFQFSRTQTPMVYQVDPPSGVPGKLIHVYGWIMTGRLET
FDFDAEYIDSPLLLEA---------QGEKWVTPCSLVNRKTGHCYPIQEDHGLGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SMVHKS-AWLVSAKQE----LFLYQTYPXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXARLSGFFVAPETNNY
TFWIQADSQATLHLSQSETQGTKV-KVASTKVGTADWFDSWEQNG---NEGNWQQKTSKL
ELFGGARYYLEAEQYGRAPSRGMRIGVQIHNTWLTPDVVSTYLREKHQIKIHAQKTPEIQ
MLTVSG-GGSFSLTWDNVSSQSIPANATAHEIQKALEELLAVKCQLEPLSANILLRLGFE
QGL-EGFSSDGDLTNRIEPFCGRFSLQQPRYLVLKPLAGQKGYQLEQYAYLCLAYKSHTN
KILKVTVYFTTALQNDVMKNITCDWSL----MGTGSGSWQFMCTDLWRTCVHGSVHLLTP
LVNAPMLVHQIDLLPLA---QKPDVFYVDEVIIADRNLTVSQADSGTARPGGNLVELLSV
VGSPPIYNMTAWFSGCGQELPLITIXXXXXXXXXX---------XXXXXXXXXXXXXXXX
XXXXXXXXXXXXX-XXXXXIPVHISAGHLHQLLRNNSDNFTSRYLDASDFMVIENQKSCY
EHVWTLSWSTQVGDLPNFMQ---VSAENMTGVNPIATTRVVYDGGVFLGPIFGDMLVTPN
QYTQVVVQVNDIPAHCSGSCTFQYLEGSTPQVHLVQYSQDGDT---NLLVNFIGTSFSGD
SQFLQIIVNKTNCKIIFSNHTYVVCQTTLLPMGVHQISMLVRPFGLAVGTNG-EDLFLNV
EPKLDA-VDPSKAAEIGGLWATIQGSSLENISEVLFGSQSCAMNVMISNSRRIHCRVPPM
EKDE-PIVNITVISRDYTALLPMAFT YVSLLN PVINSLSRNRSNIA--GGEILFIGMTF-
-QPSYTDLNVEVRIQDTPAQVHSQTALGLEVVLPPLPAGLHEISVSINGINILAEGXXXX
XXXXXXXXXXXXXXXXXXXGTILSISGIGFSRSPALFWVLVGNQSCDILNSTETSIWCET
SPAPNLPG-EGALT--VPAPIEVWTGNMPFTKGPSPSLVGEGFTFIYEAASTPVVTSTRE
EIVNNTLRIYVGGENLSNSKILLEDLACDLETQTF------------KSNTSLSVCSFPL
HSLEAGIYLLRVWQKKMGFADMSAVFQQFVMMPQIMSIFPAQGSACGGMILTVKGL-ALS
SRRSLVQVDLS--DPFICTILSLGYHTIVCQINLMSNPLPG-----TSYTL----NVTVS
ANGLTSECLGNCTLSLREDSSPIVVDLTTNINERMTTLQIVGQQLGTTADEPIVFVDDYL
PCMVTFFNAS-HVTCCINDLTPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGGKLVHVF
GAGFSPGNISAAVCGAPCHVLANASVSAFSCLVLPLDVSLAFLCDMKPEEESCEATTCTY
IQCDLTVAVGMNRLLEPWPYLFICEEIPQYVSIPSHWPE---SVFST-ITGLFISPKVER
DEVLIYNSSCNITMETEAKIECETPNQPITAKITEIRKSWGQNTQXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXGKLIFLDPGPVELKAHSILVS
DGGELRIGSKDKPFQGRAQIKLYGSSYSTSFFPYGVKFLAVKNGTLSVHGSLPEITVTHL
RTAAYAGDSVLALKDAVDWHPGDAAVIISGTGVQGAKPVEEIVTVETVHNADLHLGSPLR
YSHNFTEYWVDRDHHIFGTTVP-LSRSVTIXXXXXXXXXXXXXXXXXXXXXXXTLQDCFY
SKSEKVLGSRDLGAKVIIQSFPEEPSQLQLNGVEFRDLGQAFQKHLSSVTLVGV--MRXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXX-----XXXXX
XXXXXXXXWSEQGNIIRNNVIMRVSGAEGLSSSEMLTPAGIYILSPTNVVEGNKVCAAGY
GYFFHLVTSKTSQAPLLSFAQNVAYSCARYGLFVFPKYQPPWDDVTGPTLFQNFMVWGSA
GGARI-FRSRNLHLKNFQVYSCRDFGIDILESDANTTVTDSFLLGHFAHKXXXXXXXXXX
XXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXGFTVRTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKYRSHILASMETLSASCLINASFSQIVHGSVCGEDTLFHRMS
IGLRNAPSVSYDLIITDSRNKTTTVNYVHDTLSNCYGWMALLLDQESYSLYPQ-TPWIN-
ESLQYSAIFDNFSSENYLLMVHTI-LWSYP---EILIKCGSQVGRSLPSLPAHGQNQGCD
WFFSSQLKKLTYLVSGEGKVQVVPCGEKGT-PPANSTSTSEPESILRWSLPEAWAGVEKG
WGG--YNYTIPVPGDDVLILPNRTVLVDTTLPFLKGLYVMGTLEFPVDQSNVLSVACMVI
AGGELRV--GTLESPLEKEQKLLILVRASEGVSCNRFNGILIDPGTIGVYGKVQLHSTYP
KKFWTYLGADIAAGNERIIVEDTVDWRPHDKIVLSPSSYEPHEAEVLTVKEVKSHYVQVY
ERLKHRHIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
VLQLFN---VEIQNFGSILSSSIEFTNVSTGSWIISSTLHQNCGGGIHAVASLGIILKDN
IVFDTAGHGIDLEGQEYSLSNNLVILIRQSAWSTVWVAGIKVNQARTITLHGNVVSGSER
FGFHIKGHPCSSPEAHWSDNVAHSSLHGLHLYKENGLDNCTRISGFLAFKNFDYGAMLHV
ENDLVVENITLADNAIGLLAIVYVSSVSQRSIKNVQILLKNSVIVATSSSFDCIQDKMKP
YSANLTSADRAPSNPRGGRVGILWPMFTSEPNQWPQEPWHKV-KNGYSIPGIMKLE-DVT
FSSFVRSCYDDDLDVCILPSAEYTGIMYPIIAERTNMMKINDRNKFYFPQLQS-RKDLGI
LACSESDYENPRKYLYKDLDGQSLGLPPPVSVFPKTEAEWTKSFFN--TGTFREEQKCTY
QSVMQGYICKQTDQVILILDNIDSSWAMQKLYPVVSVTGGFVDTFISINANNLCSTSESI
SMFYSIIPTGKITKVCFMHQTPQFLRFFLLGNKNTSKLLLSVFYHELQSPRVFLGGNFIL
PTTVQSAPSLLDESVGANHFDIMDNLLYVVLQGEEPIEIHSSMSVHLALTVKYSILDKPW
EIMILERLTTFLQISQYQIRFIHEMSGKKTTLKAIADNAAKRTRNCPTMTCTSY-Y-RVG
HRRTLMMEKNS--YIPRTTTTEIISKVIAIEISDHPTVRNAELIPPLSRNKLQSIAQQVV
TAQQTGVLENVLNITIEALLM-TRSNGVFS---YGNTSNFKTGNLIYVRPYALSILVQPS
DGDVGKELPVQPHLVFLDKQNQRVESLGLPSEPWTVSVSLEGRPGSMLK--GCT-QAETQ
DGYVSFSNLAVLISGSNWHFIFTVTSPP-GVNFTARSXXXXXXXXXXXXXXXXXXXXXXX
XXX--XXXXXXXXXXXXXXXXXXXXIKNEEITEPQINDQKS----H-LHISSKQ------
QVSQVD-IMKEDTIMREDMRKKVMLS-RL-NQLPQQ-SLNGVSRRKVSSLAIREEE----
-SSQEEVTVPAPRTTTVTFGKH-TSAPGSPAQQVYLQESGNCKEVQEQLLRYQLAG--QD
QLMQ-LCPDIRQNMHQLQ-DQNRLGKKRGSSVVSQEKKTSYDDTEAFCLHSVHPEAIQEQ
L-------------------------

-------MTIWLMSLMSIEVLLSAVPCLSLRIEPGEGSLAGGTWITVILDGLG---LGVL
YPTNGSQLEIHLVNMNLAVPALPSIPCDVFPVF--LDLPVVTCQTRSLP--SGAHEGLYS
LEVHFGGQAVGSLSPGPRDNCTFKYSKAQTPIVYQVNPPSGVPGTLIHVYGWIITGKLET
FDFDAEYIDSPLILEA---------QEDNWVTPCSLVNRQTGSRYPIQEDHGLGTLQCRV
EGHY-IGSQNVSFSVFNRGK-SMVDKS-AWLISAKQE----LFLYQTHPEVLSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRHA--SPRKIECTTRAPGKDVRLAAPQAGNR
GLLFEVGDAADGLALTEATPGYRWQIVPNASSPFGFWSKEGRPFRARLSGFFVAPETNNY
TFWIQADGQASLHFSWSEEPRTKV-TVASIGMGTVDWFDSWEQNG---GEGLWQQKTPKL
ELLGGAKYYLEAEHHGIAPSTGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEIQ
MLNVSG-TGHFLLTWDNVSSHHNPFPAHMLGSS-----------VLFNIHAVFLFLSELH
PGL-EVSSSDGELTSGSEPFCGRFSLYQPRHLVLKLPAAQKGYRLDEYTHVSSSQVGHVN
KILKVTVSFTIGFHNVAQKNVTCDWTL----TSTSPQSWGFTCTDLWETCVGRSWDVQPP
LANSPVLVHRIDLLPQA---QGTGLLFVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
AGSPPVYSVASWPAGCGTELPLITARSVPMEGTEE---------GSGLVQVATQRLQRTS
PPLGGHFRIQLSN-AVIPDVPVNISASDLHKLLQDNADDLTSRYLNASDFSVKEDLSCCY
EHVWTLSWSTQIGDLPNFIR---VSDGNLTGVNPIATARVVYDGGVFLGPIFGDMLATVN
QHTQVVVQVNDIPAHCRSSCSFQYLQESTPWVHSVWCSPDGDV---NLLVYITGTGFSGD
SQSLQVRVNQTSCKVIFSNQTTVVCRTDLLPVGVHRISMLVRPSGLAVNASG-EGLFLSV
EPRLDA-VEPSRAAEIGNLG----RACLEGVSLVLFGSQSCAINATPSNSRK------SM
GKDG-HIVNVTVIRGDHSAVLPRAFTYVSSLNPVIVTLSRNRSNIA--GGETLLIGMTS-
-LVNYTDLAAEVHIGGTCAPVRAQTPGGLQVALPALPAGLHGISVSVNGVSIRSQGVD LH
IQYITEVF SIQPCCGSLLGGTVLSISGIGFGRDPASVWVLVGNQTCATVNFTEVSIWCET
SPAPQLPD-ADAPT--VPAPVEVWAG NVSFTRGNSPVLVGKGFTFTYEAAATPVVTAMRG
EITNSSLRLYVLGSNLSNSVVLLGSLSCDLETLSL------------QTNVSLSGCSFPL
CRVEAGIYPLQVRQEQVGFANMSAVPQQFVLT PRIVAIFPTRGSACGGTVLSVRGL-ALT
SRRRSVQVDLS--GPFTCVILSLGDDTVVCRVNPVGDPSPG-----ASFIL----NVTVL
VNGLTSECQGNCTLFMQEETTPVVDAVTLDISGSLTTVLIRGQRLGIMADELLVFVDDQL
PCSVTFFNTS-YVACQISDLIPGLHYLSVSHPRNGYACSANSSRYFYVMPQVFHYFPKNF
SIHGGSLLAIEGTALRGQNTTSVYVGQQACLTVSI-SAELIQCVVPAGNGSVALEIEVD G
LLFHLGVIGYSCAFTPELLSISQSDD-VLTFAMAQISGAENVDIFIGMSLCVGVSA----
NHTVLQCMVPSLPAGEYQVRGYDRVRGWASSVLVFTLRVRITAVTGNFG-CLGGRLVHVF
GAGFSPGKISAAVCGAPCRVLANATVSAFSCLVPPLDASVAFLCALKHGEDSCEATSHTY
VQCDLTVAMGTERLPESWPYLYACEESSQCLFVPDHGTE---SEFPSSLSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITAKITEIRKSRGQNTQGNFSFQFCRRWSRVH
S WFPDRMPQDGDNVTVQNGQLLLLDTNTSIL-NFLHVKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGKAWIKLHGSSHSTSFFPYGVKFLAVRNGTLSLHGSLPKVLVTCL
RAAAHARDTVLALEDAVDWQPGDEVVVISGTDVEGATPMEEVVTVETVHKADLYLRSPLR
YSHNFIENWVAGENHILKATVALLSRSITIQGNLTDERMELLASCQEADASEGNLQPCLY
STSEKMLGSRDLGARVIIQSFPEEPSQVQLKGVQFRDLGRAFHKHLSSLTLVGA--MRDS
YVQGCTVWNSF-SRGLSMCRTAGLKVDSNVFYNILGHALLVGTYMEIRHI-----SWEAV
PGRKN--DWSERGNIIRNNMIIRVSGAEGLSNPEMLTPSGIYIRNPTNIIEGNRVCAAGY
GYFFHLVTSQTSQAPLLSFTQNMAHSCTRYGLFVYPKFQPPWDNGAGPTLFQNFTVWGSA
GGAQI-FRSSNLHLEKFHVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---VSLCMSA
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSGCSQGQGGFTVKTNQL--KFINSPNLVA
FPFPHAAIVEDLDGSLSGKNRSHIVASMETLSTSCLVNANFSRIVPGSVCGGGVLFHRMS
IGLANAPDIPYDLTLTDSRNKTTTVNYVRDTLSNPHGWMALLLDQETYSLRFE-TPWIN-
TSLQYSATFDNFAPGSSLLLVHTD-LPPAP---DVLIRCGSHVGLSLPFLPSPGQNQGCD
WFFDHQLRQLTYLVSGEGQVQVILQVTEGV-SPTISVSTSAPGSALKWSLPETWQGVEEG
WGG--HNHTIPGPGDDVLILPNRTVLVDTDLPFLRGLYVMGTLEFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRFNGIRVDPGTIGIYGKVQLNSAYP
QKSWTR LGADIASGNERIIVEDAVDWRPHDKIVLASSSYEPHEAEVLTVKEAKGHHVRIH
ERLKHRHIGSVHITEDGRRIRLAAEVGLLTRNIQIRPDTSCGGRLLVGSFRKSNQEEFSG
VLQLLN---VEIQNLGSPSYSSIE FTNVSAASWIRSSTLHQSCGGGIRAAASHGIHLHDN
VVFGTAGHGMDLEGQAYSLTNNLVLLVTHSAWSNVWVAGIKVNQAKDIALRGNVVAGSER
VGFHIRGHQCSLPDMLWSDNVAHSNLHGLHLYKESGLGNCTGISGFLAFKNYDYGAMLHV
EDSVEIENTTLVDNAIGLLAVVYVSPASQSSIRNVHIVLRNSVIVATSSSFDCIQDRVKP
RSANSTSADRAPSNPRGGRVGILWPVFTLEPNQWPQEPWHKV-RNGHSISGIMKLQ-DVT
FSSFVKSCYSNDLDVCILPNIENTGITHPITAERTKMLKIKDKNKFYFPPLQP-RKDLGR
VVCPESDCESPRKYLFKDLDGRALGLPPPVSVFPKTDAEWTGSFFN--TGTFREEQKCTY
RSLMHGFICKQTDQVVLILDNADATWAIQKLYPVVSVTSGFVDTFSSVNANIPCSTLRSV
STFYSILPTRQITKVCFVDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPRVFLRGSFIP
PTVVQSASLLLDESIGVNYFNIIDNLLYVVLQGEEPVEIRSGISILLALTVTYSVLEKDW
GIMILERLTDFLQIGHNQIRFVHEMPGDEATLKAIADNRAKRKRNCPTVTCVSH-YRRVG
QRRPLVMEMNS-YEDSPPTTMETISKVIVFEIGDLPTVRSTVMIPSLSSNKLQNLAHQII
TAQQTGALENNLNMTIGALLV-TQPKGVIG---YENTSSLKTGNLIYMQPCALSILVHPS
DGEVGKELPVQPQLVFLDKQNRRVESLGTPSEPWTVSASLEGAPDSVLK--GCT-MAETQ
DGYVSFSNLAILISGSNWHFVFAVTFPP-GVNITARSRPFAVLPVTRKEKSTIILAASLC
SAVSWLALSCLVCCWFKKSKS-HRKTKPEEISESQTNGQKD----R-IHTSSKC------
RGSQAG-TEKEETVVGEGVRMEVMPC-KL-SQLRHQ-SHNGVCRRKVSRHAVPE------
-----EAAVPAPSSTGTTSPGH-TCAPGSPAQQTHLQETGNRKDAHEQLLRYQLAG--HG
QLLL-LCPDLRQDRQKLP-GQSRLSKESGSLGLSQEKKATGGDTEAFCLHSVHPETMQEQ
L-------------------------

-------MTVWLISLMSMKILLLAEPSLSFHIEPEEGSLAGGTWITVIFDGWE---SELL
YPTNGSQLEIYLVN--VAVPALPSIPCDVSPAF--LDLPVLTCRTRSLL--SEAHEGLYY
LEMHSGGQVGGSPSPGPRDNCTFKFSRGQTPIVYQVTPPSGVPGKLIHVYGWIITGRSET
FDFDAAYIDSPLILEA---------QGGKWVTACSLVNRQTGSGYPLQEDHGLGTLQCRV
EGNY-IGSQNVSFSVFNKGKRSMVHKN-AWLVSAKLD----LFLYQTYSEILSVFPETGS
LGGRTDITITGDFFDNPAQVTIAGIPCDIRHV--SPRKIECTTRAPGKGARLTAPQAGNR
GLLFEVGDAVEGLDLTSATPGYRWQIVPNASSPYGFWSKEGQPFRARLSGFFVAPETNNY
TFWIHADSQASLYLSQSEDPRTKV-KVASVRVGIADWFDAWEQNG---HEGTWQWKTPKL
ELVGGTRYYLEAEHCGVAPSRGMSIGVQIHNTWLNPDVVSTYLREKHQIRIHAQRLPEIQ
MLTVSG-KGSFSLTWDNVTSQPIPANATAHQIQTAIEELLAVKCKLEPLSASTLLWLGFE
QGP-EGSSFEGDLTSGTEPFCGRFSLHQPQQLVLTPPASQKGYRLDRYTHLCLAYKGHMN
NILKVTVFFTTDPQNFIEKNITCDWSL----VGTRPNSWRFTCTDLWETCVRRSVYLQPP
LANSPVLVHRIDLFPLS---QETGQFYVDEIIIADTNITVSQADSRTARPGGNLVESLCV
VGSPPVYNVSFSLVECGRELPLITASSVPTEGGEE---------GSRLVQVTTQRIQRTS
PPLGGYFRIQLPT-TVIPDVPVHISASHLLKLLQNNADNFTSRYLNVSDLTVKEDLKSCY
EHVWTLSWSTQVGDLPNFIR---VSDENLTGVNPEATTRVVYDGGVFLGPVFGDMLVTAN
QHTQVAVRVNDIPAHCSGSCSFQYLEGSTPQVHSVWYSLDGDI---DLLVYIFGTSFSGD
PQAVEVMVNKTICQVLFSNQTNVVCQTDLLPVGKHRLSVVVRPSGRAINASG-EALFLNV
EPRLDA-VEPSRAAEIGGLWATIQGSGLEDVSLVLFGSRSCAINITTSNSRRIQCKVPPR
GKDG-PVVNLTVITGDHSAVLPMAFT YVSSLN PVIMSLSRNRSNIA--GGETLFIRMAF-
-LVNDTDLDVDVHVQDAMAAAHVQMPQGLEVVLPPLPAGLHRISVSINGLHMRSRGVDLH
IQYI TEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRTCDILLLTETIIQCET
PPIAQLPP-ADVPA--VPAPVEVWAGNVSFARGPLPSLVGKGFT FIYEAARTPVVTAVQG
EMTNSSLRLSVEGNNLPSSVILLGVFSCDLETQSL------------RSNMSLSGCSFPL
QSFEAGIYPLQVRQKQMGFANMSAVLQQFVMT PRIMAILPTHGSACGGTVLTVRGL-ALN
SRKRSVQVDLS--GPFTCVILSLGDQTVLCQINRVGDPLPD-----ASFTL----NISVL
VNGLPSE CQGNCTVFLQEETT PIVDSLTTNISGSLTMVLIRGQKLDITADEPMVFVDNHF
PCAVTSFNSS-HVACWIRDLTPGLHYVSVFRTRSGYACFGNVSRH FYIL PQVFHYSPKNF
SIHGGSLLTMEGTALRGENSTLVFVGQQPCLTVSI-SSELIQCIVPAGNGSVGLVIEVDG
LSYHMGVIGYSNAFTPQLLSISQTDD-VLTFVVAQVSGAENVDIFIGMSPCAGVSG----
NHTVLQCVVTSLPAGEYPVRGYDRTRGWASSVLVFTSTVTISAVTENFG-CLGGRLVHVF
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDVSLAFLCGLKHAEESCEASSSTY
VQCDLTVTVGTETLPQSWPYLYICEESPQCLFAPDHWTE---STLPR-FSGLFISPKVER
DEVLIYNSSCNIAMETEAKMECETSNQPITAKITEIRKSRGQNTQGNFSFQFCLRWSRAH
SWFPERVPQDGDNVTVENGQSLLLDTNTSVL-SLLHVKGGKLIFVEPGPIELRVHSILIS
DGGELRIGSEDKPFQGKAGIKLYGSSHSTPFFPYGVKFLAVRNGTLSLHGLLPEVTVTHL
RAAASAGDTVLALEDAVDWRPWDEVVIIGGIGVEGARPTEELVIVEAVHNTDLHLRSPLR
YSHNFTENWVAGERHVLKVMVVLLSRNVTVQGNLTAERREHLTSCQEASASEGNLQDCLY
SKSEKMLGSRDLGARVIVQSFPEEPSQVQLKGVQFRVLGQAFRKHLSSLTLVGA--MRDS
YIQSCTVWGSF-SRGLSMSRTMGLKVDSNILYKISGHALLVGTDMDIKYI-----PWKET
SAKKM--DWSEQGNIIRNNVIISVSGTEGLSSPEMLTPSGIYIRNPTNVVEGNRVYVAGL
GYFFHLVTSQTSQAPLLSFTKNIAHSCTRSGLFIYPQFQPPWGNGRGPTLFQNFTVWGSA
GGAQI-FRSSNLHLKNFQVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSA
GIKTPKRWELIISNTTFVNFDLTECVSIRTCAGCSRGQGGFTVKTNQL--KFINSPNLVA
FPFPHAAILEDLDGSLSGRNRSHILPSVETLPASCLVNAGFSQIVHGSVCGEDVLFHRMS
IGLDNAPVVSYDLTITDSRNKTTIVNYIHDTLSNLYGWMALLLDRETYTLQFE-TPWIN-
RSLQYSATFGSFAPGNYLLLVHTV-LWPYP---DILVRCGSQVGRSLLSLPSPGQDQGCD
WFFNTQLRQLTYLVSGEGNVQVTLQVKEGV-PPTISAATSAPESALKWSLPEAWTGIEKG
WGG--HNHTIPGPGDDVLILPNRTVLVDTNLPFLKGLYVMGTLEFPVYRSNVLSVACMVI
AGGELKA--GTLKNPLEKEQKLLILLRASEGVFCDRFNGIHIDPGTIGVYGKVQLHGACS
KKSWTHLAADIASGNERIIVEDTVDWRPRDKIVLSSSSYEPHEAEVLTVKEVQAHHVRVH
ERLKHRHIGSVHVMEDGRYIRLAAEVGLLTRNIQIQPDTSCMARLLVGSFRKSSSEEFSG
VLQLSN---VEIQNFGSPLYSSIELTNASAGSWIISSTLHQSCSGGIRAAASHGIILNDN
IVFGTVGHGIDLEGQNFSLSNNLVVLMTQPAWSTMWVAGIKVNQAKDVNLYGNVVAGSER
LGFHVRGHRCSSPEARWSDNVAHSSLHGLHLYKENGLDNCTGISGFLAFKNFDYGAMLHA
KNSVELDNLTLVDNTIGLLAAVCVSSAAQGHTENVQILLRNSVIVATSSSFDCIQDRVKP
RSANLTSTDRAPSNPRGGRVGILWPVFTSEPNRWPQEPWHRV-RNGHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNVENAGIMHPITAERTRMLKIKDKNKFYFPPLQA-RKDLGM
LVCPESDCENPRKYLFKDLDGRALGLPPPVSVFPETEAEWTGSFFN--TG----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------RMTGWLISL-SFEVLFLAVPHPSLHIEPREGSLAGGTWVTVVLDGR-----CVL
HPANASQPEIHLVNV--ALPTLPRVPCDVSPVF--WDLPVVICQTRALL--SEGQAGTYA
VEVRSGGQVVGGPGPGSHDNCTFKFSKAQTPLVYQVSPPSGVPGQLIQVYGWIITGRLET
FDLGVEYIDSPLVLEA---------QGDKWETPCSLINRQNGSSYPVREAGGIGTLQCRV
DGSY-IGSQLKRTRLQM--FHAINRGG-AWLVSAKQD----LFLFQTHPEILSVFPETGS
LGGGTDITVTGAFFDVPARVTVAGIPCDISRV--SPREITCTTRAPGKGTRLTAPQAGNR
GLLFEVGAASEGSELTEASPGYRRQIVPNASAPLGFWSQEGQPFKARLSGFFVAPETNNY
TFWIQAGSQASLHLSWSEEPRDKVARVAFIGVGTADWFDSWEHG----DAGVWQQKTPKM
ELRGGAKYYLEAEQQGRAPSAGVRIGVQLHNTWLTAGQVATYLREKHQLRARAQRRPEVQ
MLDVSG-PGNFFLTWGNVSSPPLPANATAHQVMLFLSNIH----------ACLPVFPELH
PGL-EASSSDGVLTCATGPFCGRFSLCQPGHLVVTPPVAPKGYRLAQFPHLCIAYKGHAN
TSLRVVVTFTAGSAGVP-ENITCAWSP----APAGPERWRFACTDLWDTCVRHSRGLRTP
SASVPVLVQQLSLFPRA---PETDVLCVDEVIITDTNLTVSQADLGTARPGGNLVESVSV
VGSPPLFNVSVWPAGCGLQLPLLTACSVSSEAAGG---------GCG-RRAPARRLQRPS
PPLGGHFSLRLLH-TVIPDIPVGTSASGLHQLLRDNAQGAPCGPLKAADFTVEE-QGSCY
ERVWSLSWPMQTGDLPDMIG---VSHHNLTGVDATAEVRVVYDGGVFLGPIFGDMLATAN
PQAQVVVEVNGVPAHCAGPCSFQYLPGVTPRVRSVWYSLDGDT---NLLVYMTGVGFSAT
AQALQVTVNRTSCQVVFSNQTNVVCRTGLLPVGVHQLSVWVR PVGLAVSESG-EGIFLSV
ETRLEA -VEPARGADTGGLWALIRGPRLDGAHLVLFGSQSCTINATASNSRRIHCRVPPR
GEDG-YTVNVTVVRGGHSAVLPGTFTYIPSLSLVVVSLSRNQSNIA--GGEPLFLGVTQ-
-LENYTDLEVEICIQGSLAQLHAWTAWGLAVVLAPWPPALHRTSVSI---HVGSHGVDLR
INCTTEVCTMSPCCGSLLVPKPRVQ-----------------------------------
-------A-----R--TPFPKH-----------A-HTALGYGWNPVEEQ-----------
------------------------------------------------------------
-----GPEP---------------------------------------------------
-EERSL-------------------------------------------RI--------L
TE----------------------------------------------------------
--------AA-H------------------------------------------------
---------------------------------------------AAG--KRRLPVECDA
------------------------GR----------------QVRL--------------
--ASQRCS------------------------------------FAP-QGCLGGQLVHAC
GAGLSPGNISAAVCGYPCQVLPNTTAPALGCLLLPLDVSVAPLCDLQPRGDTRGKARHTH
VQCNLTVTVGTEMLPKAWPYLCVCEQRLQDLLASDHGTE---PASLS-FLGLFVSPKVER
DEILIYNSSCNITMETEAEMECETPNQPITAKITAIRTSGVHSTQGGFALQSCRRWSRAC
SWRSAGMPQDGANVTVEKGQWLLLDTNTSLL-NSLHIRGGKLIVLGPGPVELRAHSILIS
DGGELRIGTEDKPFEGMAQITLHGSSHSTPFHPYGVKFLALRNGTLALHGALPEVTVTCL
RAAARAQDTMLALEDAVAWRRGDEVAVISGAGGEGAQPVQETVTVEAVHGADLQLRAPLR
YSHNVTEHWVAGERLALKAVVVLLSRKISIRGNLTSERVELLTSCQESSTSEDDLKHCLY
SKSEKMLGSRDLGARVIIQSSPDEPSLVQMRGVQLRDLGQSFRKHGSAVTLVGA--LRGS
YVHGCVVRNSF-SRGLSLLRTWGLRVDSNVFYKISGHALLVGMYMDIRNP-----AQDAP
PGRKW--DRSEQGNIITNNVIIGVSGAEGLSSLEMLAPSAIYIRSPTNVVEGNRVYGAGY
GYFFHLVTRQTSQAPLLSFTQNKAHSCTRSGLFVYPKYQPPWDPDMGPTLFQNFMVWGSA
GGVQI-SRSSNLHLKNFQVYSCRDFGFDILESDANTSVSNSLLLGHFAEE---RNLCMST
GIKTPKRRELMISNTTFVNFDLFNCVAIRTCSGCSPGQGGFTVTTKQL--KFANSSNLVA
FPFPHAAVLEDVDGSLSGKNGSHILASVETLSASCAANASFSGLVLGSVCGEDVVFHRMS
IGLANAPDVSYDLTLIDSRNKTTTVNYVHDTLSNHHGWVALLLDRETYSLQFE-RPQRD-
RSLQYSATFYNFAPGRYLLLEHRD-APPHP---DILLTCSGRLGHSLPSLPSPGRDQHCD
WFFNAQQRRLTYLISGEGQVGVTLQVMEGA-PPTLSASTSEPNGPLPWSHPETWQDVGEG
WGG--YNSTLPRPGDDVMIPPNRTVLVDIDLPWLRGLYVLGTLEFPVDRSNVLSVACLAI
LGGELRA--GTLENPIEKERKLLIHLRASEGVSCNRLYGIQLDPGTIGVYGKLLLHSAYP
KKSWTQLGADIAPGNERILVQEVLDWRPQDKIVLCPSSYEPHEAEVLTVRAVRGRHVSIQ
ERLQYRHLGGAHVVEDGQSIRLAVAVGLLTRNVQIRSDTACRGRILVGSFQNSTREEFSG
TLQLLN---VEIQNLGSSLSSSIEFSNASGGSWMMSSVLHRSCGGGVRASASPGLVLKDN
VVFGMVGHGIDLEGPAYSLLGNLVVLVTQPAWSTPWVAGIKVNRAPGVSLRGNIVAGSER
LGFHVGGHGCSP-QVLWSDNVAHSSLHGLHLYKDGTHEGCTGISGFLAFKNFDYGAMVHA
ENSVVIENLSLVDNTVGLLAVVYVSSTSLSSIKHVQIVVKNSTIVATSSSFDCIWDRMEP
RSANSTSPERPPSNPRGGRVGILWPAFTAEPNQWPQEPWHRV-RSGQVVAGIMKLQ-DVT
FSNFVRSCHGDDLDICILPNAENTGMVPPVTAERTRMLKIKERNKFCFSPVIP-RKDLER
VICPESNCENPKKYLFKDLDGKTLGLPPPVSVFPKIEAEWTGSFFD--TGVFREEQKCTS
PWPMQSFVCSEADHVVLGLTSAHVTWANRKLYPVVSVTNGFVDTFSSAQASPGCSTSSSV
STFYSILPTRQITKVCFVDQTPHTLQVFLLGNRNSSKLLLALFYHELQSPYVFLRGSLVP
PAVVQSVSSLLEEPAGANHFSIMDNLLYVVLQGEEPIEIRTSVSIHLAFTVITASPEKGW
EMILLERLADFLQINTSQVRLTHEKSGNEETLKTIADSRAKRKHTCPTVTCASD-SRSIS
LRRPLAVEMSS-YLVFPATSLETISKVIVVEIGDPPAVRSTGETPSLPSSKLQSLAGQLI
TAQQTGQLEAILKVTVGALLV-TQPAADLS---CGNASSPGPGSRVYVRPYALSVLVQPS
DGEVGKKLVVQPRLVVLDRQNRRVESLGMPSAPWIISVSLEGSADSALT--GCT-RAETQ
DGYVSFSDLAVLVSGSSWHFTFTVTSPA-GVNFTARSAPFAVLWVAGKERSAVALAAVLC
AVISWLALCCLLCCWFKRSRS--RKTKPEETPESQMNDSDH----H-IRVSARR------
QGSQEG-TAKDCAVVGEDLRLKVAPN-----HCLLR-SLDGVSRRKVGQDPARE------
----VEATVPAPR-----------------------KMTRDWKEVQQQLPRYQLAG--RD
QLLLLRCPERRQDRWLWP-GPSRGSQERSSLGLSQEK-----------------------
--------------------------

-------MIVWLISLKSIQMLFMAVSCLNFHIEPEEGSLAGGTWITVIFDDSE---SGLF
YPANGFQLEIHLVN--VTVSVLPSIPCDISPVF--LDLPVVMCRTRSLL--SEAHEGLYY
LEVHSGGQVVGSPKPGPQDSCTFKFYRAQTPIVYQVYPPSGVPGKLIHVYGWIITGKLET
FDFDADYIDXXXXXXX---------XXXXXXXXXXXXXXXXXXXYPIQEDHGFGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SMVHKN-AWLISAKQE----LFLYQTYSEILSVFPETGS
LGGRTDITITGDFFDIPAQVTISGIPCDVRHV--SPRKIECTTRAPGQGARLTAPQAGNR
GLLFEVGYAAEGLDLTEATPGYMRQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLYFSRSEDPRSKV-KVASIRMGTADWFDSWEQSG---DEGPWQQKTTKL
ELFGGAKYYLEAEHHGRAPSRGMKIGVQIHNTWLNPDVVSTYLREKHQIRIRAQRLPEIQ
MVTVSG-RGNFFLTWDNVSSQPISANATAHQIQTAIEELLAVKCQLEPLSANILLQLGFE
QGS-EGFSCDGHLTSGTEPFCGRFSLYQPRYLILRPPAAQKGYRLDQYTHLCIAYKDRMH
KILKLIVSFTIGLQSIIKKNITCDWSL----MGTSSESWQFTCTDLWKTCVHPSAYLQVL
LKNSPVVVHRIDLLPLA---QETGAFYMDEIIIADTNLTVSQADSGTARPGGNLVESVSV
VGSPPVYNVTSWLAGCGPELPLITASSVPTEEAEE---------GSRKVQVTTQRLQRTS
PPVGGHFRIQLSN-TVIPDVPVNISASHLCQLLQNNTDDFTSRYLNVHDFTVMEDLKSCY
EHVWTISWSSQVGDLPNFIR---VSGENLTGVNPAATTRVVYDGGVFLAPIFGDMLVTAN
PCTQVVVRVNDIPAYCSGSCSFQYLEGSTPWVHSLWYSLDGDI---NLLVYITGTSFSGD
SQAFQITVNKSNCKVIFSNQTNVVCQTNLLPVGVHRMSMFVRPFGRAINASG-EGLFLNV
EPRLDA-VDPSRAAETGGLWATIRGSSLEDISLVLFGSQSCAINITTSNSQRIQCRVPPR
GQDG-PIVNVTVIRGDHSAVLPMAFT YVSSLN PVIMSLSRNRSNIA--GGEILFIGMAL-
-LVDYTNLDVEVYIKDTLAWVHAKTAQGLEVVLPPLPAGLHRISVSINGVDIYSAGVDLH
IQYI TEVFSIEPCCGSLLGGTILSISGIGFSREPGLVWVLVGNQSCNIVNLAETHIWCET
SPASLPPE-ADILT--VPAPVEVWVGNLSITQGPAPSLVGKGFT VEEKSQTTPVVTAVRG
EITNSSLRLYVEGNNLSNSVILSEN-MSSLETQSF------------RGNTSLSGCSFPL
HGLEAGVYPLRIRQKQMGFANMSAAPQQLVMT PWITTISPTNGSACGGTVLMVRGL-ALN
SRRRSVQVYLS--GPFTCVILSLGAQMVLCQIKPVGDSLPG-----ASFTL----NITIL
VNGLPSECHGNCTLFLKEETTPVVDALTTDINGSLTTVLIRGQRLGTTADEPMVYLDDHL
PCIVTFFNAS-HVACQISDLTPGLHYLSAVHTSNGYACSGNVSRHFYILPRVFHYFPKNF
SIYGGGLLTIEGTALRGQNSTVVYLGQQACLTVSI-STELLQCFVPAGHGSVVLDIEIDG
LLYQMGVVGYSNAFTPELLSVSHTDG-ILTLVVAHISGAVNVDIFIGMSPCVGVSG----
NSTVLQCVVPFLPAGEYQIRGYDRTRGWASSALAFTSSVSITAVTENFG-CLGGRIVHVF
GAGFSPGNISAAVCGFPCQVLANATVSAFSCLVRPLDVSLASLCDLKHEEESCETSSLTY
VRCDLTVSVGTERLPESWPYLYICEESSQCHFAPDHWME---SVFST-FSGLFISPKVER
DEVLIYNSSCNITMETEAKMECETPNQPITAKITEIRKSRGQNTQGNFSFQFCQRWSRAH
SWFPERVPQDGDNVTVETGQLLLLDTNTSVL-NLLHVKGGKLIFMDSGPIELRAHSILVS
DGGELQIGSEDKPFQGKAEITLYGSYHSTPFYPYGVKFLAVRNGTLSLHGSLPEVIVTHL
RAAAYAHDTVLALEDAVNWHSGDEVVIISGIGVKDAKPVEEIVIVETVHNADLHLRSPLR
YSYNFTEYWVAGEHHILKATVALLSRSITIRGNLTNERIKFLASCQEANASEGNLQCCLY
SKSEKMLGSRDLGASVIIQSFPEEPSRVQLKGIQFRDLGQAFRKHLSSLTVVGT--MRDS
YIQGCTVWGAF-SRGLSMFGTVGLMVDSNVFYNILGHALLVXXXXXXXXX-----XXXXX
XXXXX--XXXXXXNIIRNNMIISVSGTEGLS-NEMVTPSGVYIRSPSNVVEGNRVCAAGY
GYFFHLVTNQTSQAPLLSFTRNIAHFCTRCGLFVYPKFQPPWDNGTGPTLFQNFMVWGSA
GGAQI-FRSSNLHLKNFQIYSCRDFGIDILESDANTSVTDSLLLGHFAHN---GSLCMSA
GIKTPKRWELMISNTTFVNFDLTDCVSIKTCSSCSRGQGGFTVKTNQL--KFTNSPNIVA
FPFPHAAILEDLDGSLSGKNGSHILASMETLSDSCLVNSSFSQIVPGSVCGENVLFHRMS
IGLINAPDVSYDLTMTDSRNKTITVSYVCDTLSNPYGWMALLLDQETYSLRFE-TPWIN-
RSLQYSATFGNFAPGNYLLLVHTV-VWPYP---DIFIRCGRQVGRSLSALPSPRKDQGCD
WFFNRQLRELTYLVSGEGQIQVILQMKEGV-PPTVSASTSAPESALKWSLPEAWTGVEEG
WGG--HNHTIPGPGDDVLILPNRTVFVDTDLPFLKGLYVMGTLEFPVDRSNILSVACMVI
VGGELKV--GTLENPFKKEQKLLILLRASEGVFCDRLNGIYIDPGTIGVYGKVLLHSAYP
KKPWTHLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHNIRFH
ERLKHRHIGSAHVMEDGQYIRLAAEVGLLTRSIQIQPDISCKGRLLVGSFRKSSREEFSG
VLQLLN---VEIRNFGSPLFSSIELTNVSAGSWIISSTLHQSCGGGIHAVSNHGITLKDN
IVFNTAGHGMDLEGHAYSLSNNLVVLMTQPAWSTVWVAGIKVNQAKDINLRGNIVAGSER
LGFHIRGQRCSSLEALWSDNVAHSSLHGLHLYKESELDNCTSISGFLAFKNFDYGAMLHV
ENSIEIENITLVDNVIGLLVIVYVSSVQQSPIENVQIVLRNSVIVATSSSFDCIQDRVEP
CSANLTLTDRAPSNPRGGRVGILWPIFTSEPNRWPQEPWHKV-RKSHAISGIMKLQ-GVT
FSSFVKSCYSDDLDVCILPTAENTGIIHPITAERTKMLKIKDKNKFYFPPLPS-RKDLET
LVCPESDCESPRKFLFKDLDGRALGLPPPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
RSLIQGYICKQTDHVILILDSDDATWAMRKIYPVVSVTGGFVDTFSSVNANIPCFTSGSV
SIFYSVLPTREITKVCFVNQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTPVQSISSLLNESIGSNYFSIMDNILYVVLQGEKPIEIRSGASIHLAFTVMFPVLEKGW
EIMTLERLTDFLQISQDKIKFIHDMPGNEATLKAIADYRAKRKRNCPTVPCASH-Y-RVG
QRRPLMMEMSS-CRVPAPTSMETVSKVLVLEIGDLPTVRSTGLIPSLSSNKLQNLAHQII
TAQQTGVLENVLMXXXXXXXXXXXXXXXXX---XXNTSNFKVENLIYIRPYALSVLVQPS
NGEVGKVLPVQPQLIFLDKQNRRIESLGPPSEPWAISVSLEGTSDSVLK--XXX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XANFTARSRSFAVLPVTRSERSTIILAVSLC
SMVSWLALCCLVCCWFKRNKS--RKIKNEDISESQTNDQKN----H-SHVSSKH------
QGSQVE-TDKEDPIVGEDMRMKVMLG-KL-NELPHQ-SLNGVSRRKVSRRAVQEEG----
-GSREGAAVPAPTITGVTSHRH-TCALSPSVQQTYVQETGDWKEAQEQLLRYQLAG--QD
QLLL-LCRDLPQERQQLQ-DQSQLGKDGGSLGLSQEKKASCGVTEAFCLHSVHAEAIHEQ
L-------------------------

-------MTVWLIALMSIEGLLLTXXXXXXXXXXXXXXXXXXXXXXXXXXXVE---WDLL
CLGNGSQLELTLVNV--AVPELPAIPCDVAPVL--LDLPVVWCQTRSQL--PEAPEGLYS
LDVYSGGQLLGSLSQGPCDSCTFKFSKAQTPVIYQVNPSSGVPGNMIHVHGWIITGRVET
FDFDAEYIDSPLTLEA---------QRDQWFTPCSLVNRQTASCYSVQEDHGLGTLQCRV
EGSY-IXXXXXXXXXXXXXXXX-XXXX-XXXXXXXXX----XXXXXXXXXILSVFPETGS
LGGRTDITITGDFFDNPAQVTLAGIPCDIRHV--SPRKIECTTRSPGKGARLMAPQAGNP
GLLFEVGDGAEGVDRTEATSGYRWQIDPDASSPSGFWSKAGQPFRARLSGFFVAPETNNY
TFWIQADSPAALSFSLSEDPRTKV-EMASLKVGTDDWFDSWEENG---KEGTSHRKTPKL
ELLGGAKYYLEAEHHGIAPSRGLKIGVQIHNTWLNPDVVSTYLREKHQIRARVERQPEIQ
MLNVSG-AENFILTWDSVSSQPIPANATAHQIQTALEELLAVKCKLEPRSADILLRLGFE
QXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXX-XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXPLQAEETEE---------GSGFVQATTWKLQRTS
PPLGGHFRIQLSD-TVIAGVPVHISAGHLRKLLQDSIDSFTSTYLSASDLMVKEDVHSCY
EHVWTISWSTQIGDLPVSIR---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXVAVRVNDIPAHCSGSCSFQYLQSST-LIHSTWYSVGDDI---NLLVYITGTGFSDD
SQAFQVMVNKTSCQVIFCNLTCVVCQMGMLPVGVYQLSVLVRPSGLAITTSG-EGPFLHV
GPRLDA-VEPSRAAKIXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XGNE-SVVDVTVTRGDQWAVLPAAFAYDSSLNPLILSLSRNSSSLA--GGEILFIGTTW-
-LENSNELDVEVHVWDAWAQLHAQIPHGLEVVLPPLPAGLHGISVSINGISIRSQGIDLH
IRYLTEVFSIEPCCGSLLGGTILSISGAGFLQDPTSVRVLVGNRSCDIVNSTETTIYCET
PPAPLRSA-AGALA--VAASVHVRMGSCPFSQRPSSGSTGENFTF LYEAAATPVVTALRA
DLTGSGLQLCVEGSHVAHSAILLGGLHCELQARSC--------------NGSLAGCSLPF
RAVEAGVYPLKVRQRPMGFADMSAVAQRLVVT PRITAISPAQGSICGGTVIVVRGL-VLR
SRRKVVRVGLS--GLLTCTILGWSDQTIRCRVPRVDDPLLG-----ASISL----NVTVL
VNGLLSTC QGHCTFFMWEETT PTVSAFTMTTGGPLTTVLIQGQRFGSTSDQLMVFVDDHI
PCGVSFWNTS-QVACRVSDLPPGPHFLSVVHKTNGYACWRNVSRRFDI V PQVSRYFPKTF
GVRGGGLLTLEGTALRGQKATSVHVGQQACLSVNI-SASAIQCIVPAGNGSVVLEIEADG
RWYRLGIIGYSQAVTPELLSVSQMDD-VLTLVVAQITGAAHMDVFIGLSPCVGVSG----
NHTVLRCRVPSLPAGEYRVSGYDHQRGWASSALLLTTRATVTAVTENFA-CLGGRLMHVF
RAGFSPENISAVVCDAPCPVLENATVSAFSCLVPPLDVSLAFLCGLEPQ-GSCESSIHTY
VHCELTVTVGTVRLPRPWPYVYICEEYSQCLFEPDRWTE---PSFLL-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITAKITEIXXXXXXXXXGNLALQFCQRWSWAH
SWFPEGVPQDGDNVTVESGRWLLLDTNTSLL-NRLHIKGGKLLLMAPGPIELKAHSILVS
EGGELRIGSEDKPFQGKAQITLYGSSYSSPFFPYGVTFLGVRNGSLFLHGPVPEVLVTRL
RAAARAGDTVLALEDAVDWHPGDEVVVIGGIGIEGAKPMEETVIVEAVHNADLYLRSPLR
YSHAFKESWAAGKHLVFKATVALLSRSITIRGNLTVARRRHLASCQEDTASAGLPQGCLY
SKSEKRLGSMDLGARVIIQSFPEEPSQVRLRGVQFRDLGQAFQKHLSSLALVGA--MRXX
XXXXXXXXXXX-XXXXXXXXXXXXTVDSNVFYNILGHALLVGTYLEMSSL-----SWETS
LRRKI--DPSEQGNIIRNNVVIRVSGAEGLSSPELLAPSGIYIRNPTNIVQGNRVCAAGF
GYFFHLVPTQTSQSPLLSFTENIAHSCTRYGLFVYPEFQPPWENDTGLTLFQNLTVWESA
GGAQI-FRSRNLHLNNFQVYACRDFGIDILESDANTSVTDSLFLGRFAHK---ENVCMAA
GIKTPKRWELMISNTTFVNFDLSNCTAIRTCSGCSKGQGGFTVKANL---RFPNSTNVVA
FPFPHAAILEDVDGSLSGKRRSHILASMDTLPAFCLVNASFGQLVQGSVCGEDILFHRMS
IGLANAPNISYDLTMTDSRNKTTTVNYVRDTLSSSHGWMDLLLDQETYTLRFE-TPLIS-
RSLQFYATFDNFAPGNHLLLVHTD-LPPYP---DILISCGGQEGRSLSSLPSPAHNHSCD
WFFNRQLRQLTYLVSGRGQVQVTLQVKEGV-PPTLSASTSAPEPALKWSLLETWQGVPEG
WGG--HNHTLPGPGDDVLILPXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXX
XXXXXXXXXXTLDNPLNSEQKLLILLRASEGVLCDRLQDIDIDSGTIGVFGNFHLHSAYP
KKSWTHLGADIASGNEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXSAHVTEDGRYIPLAAAVGLLSRNIQLQSDLACKGRVLVGSFKRPGRGEFSG
VLQLLN---VEIQNFGTPEYSSIEFTNVPVGSWITSSTVHQSCSGGIRASASQGIILNDN
VVFGTAGHGIDLEGQAYCLTNNLVVLTTQSTKDTVWVAGIKVNRAKDVDLHGNVVAGSER
LGFHIRGHSCSLPEGPWSDNVVHSCLHGLHVYKETGMDNCTGISGFLAFKNFDYGAMLHV
EHSVELENITLVDNVIGLLAVVHTSSAPQSSITSAQIVLRNSVIVATSSSFDCIQDRVEP
CSANLTASDRAPSNPRGGRVGILWPGFTSEPNRWPQQPWHRV-RNSCSVPGIMKLQ--GA
FSSFVKSCNRDEINVCIRA-GENTVIMQPTTAERTRMLMVKDRNKFYFSPLQR-XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXQKLYPVVSVTDDFVDPFSSVSAHTVCSPSGSV
SMFYTILPTRQITKVCFVRQTPQVLRLFLSRTESTSKVLLAIFYHEPQRPQVFVREHFIP
PTLDQSDSPLLDESVGANHFNIMNNLLYVVLQGSEPIEIRAGISIHLAFAGMSSVLEKGW
EAVILQRLTDFLQVKQDQIRIILEMPGNEGTIRAIADNRAKRRLNCPTVACGAP-YRSAG
RRRPLMMPMTS-GSVPPPATVETISKVMVFEIGDFPTIKNMRLITSLTSNRLNNLAHHVI
IAHQTGV-ENVLNVTSGAXXX-XXXXXXXX---XXNTSMDKTENSIYIRPHVLFVSVQPS
DGEVGKELPIQPQLVFLDEQNRRVDPLGAPSEPWAIAAFLEGTSDSALK--GHT-QAETQ
DGYVSFSNLTVLISGSNWHFIFMVTFPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---
XXXXXXXXXXXXXXXXXXXXXXXXXTKAEETSESQTNDPRN----H-IPVLTKR------
QGSQRH-KKE-ASLKEEE------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

-------------------------SCTCFRIVPEEGSLAGGTWITVIFDGLE---SDLL
YPANGSQLEINLVSV--FKPASQRIPCDITPIF--LDLPVVMCRTXXXX--XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXFSRAQTPIAHQVNPSSGIPGKIIHVYGRIMTGRLET
FDLDAEYIDSPLILEA---------QGDGWVTPCSYINRQTGSXXXXXXXXXXXXXXXXX
XXXX--XXXXXXXXXXXXXXXSMVDKT-AWLISAKQD----LFLYQTHSELLSVFPESGS
LGGSTDITITGNFFDSPAQVTIAGLPCAIRHV--SSRKIVCTTRAPGSGARLEAPQRGNR
GLLFEVRDAEEDADLTETTSGYRWQIVPNASSPFRFWSNEGQPFRALLSGFFVAPETNNY
TFWIQADSPASLYFSQSEDPKAKV-KVASIREGIADWFDSWEQNG---NEKIWQQKTPKM
ELSRGARYYLEAEQNGSTPSRGMRIGVQIHNTWLNPEVINTYLREKHQIRTHAERLPEIQ
MLTVTG-NGHFLLIWDNVSSQPMAANATAHQIQTAIEELLAVKCQLEPLSANILLRLGFE
QGL-EASSSDGQLTSRTEPFCGRFSLSQPRYLDLSPLDARQGYWLHHYSQLCMAFKGHMK
DLLKVTLYFTTDFQSGIRKNITCDWRL----PRPDPGRWRFACTDLWKTCVLGSTSLQIP
QANSGCLVHRIDLLPVA---RAPGTFYVDEIIIADRNLTVFQADSGTARPGGNLVESLSV
DGSPPVYNVTSWPLGCGGELPLITASPVPSEGAEG---------GAEPIQVRTQRLQRRS
PPLGGDFRIQLSN-TVIPGVPAHISAHHLQMILQNNADDFTSRYLNASDFMVIEDQKSCY
EHVWTLSWTTQIGDLPNFIR---VSDENLTGVNAAVAIRVVYDGGVFLGPIFGDMLLTAH
QHTQVAVKVNDIPAHCSGSCTFQYLEGSTPLVHSVWYSLDGDV---DLLVSITGTHFSGD
SESLQVTVNKTSCKVILSNLTHVVCRMSLLPVGLHRVLMIVRPFGLAISADG-GGL FLHV
E PKLAA-VEPSRASEIGGTWTTIQGSNLEDVSLVLFGSQSCTINSTVSNSRRIKCKVPPR
EKDG-ATVNVTVMIGDHSAVLPMAFTYVSSLNPVITSLSRNRSSIAXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDLR
IQYITEVFNIEPCCGSLLGGTILSISGEGFSQDPDLVQVLVGNRSCVLVTSTDRSICCET
PPAPALPG-AGAVA--LTVAVIVCTGLGPLA CGPSPGLMGKRFTFTYEAAATPVVTALQG
AVVDSSLRLSVHGNHVSDAVLQLGDLSCRLGTGFP------------QKDTNWSSCSVPL
RSLRAGAYPLRVRQERLGWADLSTVSPRFVVT PQIASISPRHGSACGGTVITVRGW-ALR
PLVGSVQLRTS--GPFTCEPLSWGSQTVLCQMKPVSDPCPG-----SPRVL----NITVL
AGGLTSGCLDTCAVLLSQEATPRVEAFATQVTGALTTVLIWGQRLGSAPGELQVVVDTHH
PCTATFWNGS-HVACGVSDLSPGPHSVSVFDTQNGDACFGNISRHFHIWPQVFHYFPKNV
SLHGGSLLTVEGSALRGQNSTSVSVGPRACLTVNI-SSTLLQCVLPAGNGTQSLVLQADG
IPYQMGVIDYSPAFTPELLSISQMED-VLMLEMARISGAENMDIFIGPSPCLGISG----
NRSVLQCLLPALPAREYPVRSFDRSRGWASSALVFTSRAAVTAVTENFXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXSLAFLCGLKQGEEDCENPTPTF
VQCDLTVALGTSRLSESWSYLYLCEGSTQSFFATARWTE---SVSPT-FSGLFISPKVER
DEVLIYNSSCNITMETEAKIECETPNQPITAKITEIHRSGSQNTQXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLLPEILVTHL
RAAAYAHDTVLALEDPVDWHQGDEVVIISGEGVDSAKPMEEVVIVETVHDSDLHLRDPLR
YSHNFSEHWAAGEHHILKVTVALLSRNVTIRGNLTNERAEVLAACQETNALEGNLHNCFY
SKSEKTLGSRDLGAKVIIQSFPEEPSRVQLKGVQFRDVGQAFHKHLSALTLVGS--LRES
YIQGCTVWGSF-SRGLSLPRTWGLKVDSNIFYNILGHALLLXXXXXXXXX-----XXXXX
X---XXXXXXXXRGSIRNNVIISIWGTEGLSSLEMLTSSGIYIQNPTNVVEGNKVCIAGF
GFFFHLVTHQASQKPLISFTQNSAHSCIRYGLFVYPQFQPPWDNGTGPTVFQNFKVWGSA
GGVQV-FRSRNLHLKNFQIYACRDFGIDIVESEANTFITDSLLIGHFAQK---RSWCMAA
GIKTPKRQELIISNTTFVNFDFTDCVAIRTCSGCFRGQGGFTVITRQL--KIINSSNLVA
FPFPHAAILEDLDGSLSGINRSHILASMETLWTSCLFDASFSQIVRGSVCGEEVLFHRMS
IGLVNALSVSYDLTITDSRNKTTTVNYVNNTLSNHYGWMALLLDQETYLLQFK-IPSVN-
GCLQYSGTFDNFDPGSFLLLSHPI-PWSDA---DILIKCGSRVGRCLPSLPSPGQDQGCD
WFFNRQLRQLTYLVSGEGQVQVLLQVKEGV-SPTISXXXXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXRTVLVNTELPFLRGLYVMGTLEFPVDRSNTLSVACLVI
AGGELKV--GTSENPLEKEQKLLIHLRASEGIVCDRFSGIHIKAGTIGVYGKLQLCSDYT
MKPWTQLGTDIASGNERIILEDTVDWQPQDKIVLSSSSYEPQEAEVLTVKQVKGHHIWIH
ERLKYRHIGSVHVTEDGRTLRLAAQVGLLTRNIQIQSDLPCKGRLLVGSIRMSSGEQFSG
VLQLLN---VEIKNLGSPSYSSIELSNVSAGSWILSSTIHQSCGGGIYAAASDGIILSDN
IVFGTVGHGIDLEGQTYFLLNNLMILIRQSTWSTTWVAGIKVNLAQNITLRGNVVAGSER
LGFHIQGHRCFPPENIWSDNVAHSNLHGLHLYKDGGVDNCTRISGFLAFKNFDYGAMLYV
KNSMEIENITLVDNVIGLWAAVYGLSVPQSSTEKIQIVLRNSVIVATSSSFDCIQDRIKP
CSANLTSADRAPSNPRGGRVGILWPAFTSKPNQWPQDPWHKV-RNSHPISGIMKLQ-DVT
FSNFVKSCSSDDLDVCILPNAENTGIIHPITAERTRMLKITDKNKFYFPASQS-RKDLEM
LVCPESDCENLGKYLFKDLDGNTLGLSPPVSVFPKTDAEWTESFFK--TGTFREEQKCTY
RYEMPGYICKQTDQVVLILDNTNVIWQVQRFYPVVSVTDGFVDTFSSVNSNAPCFSS-SA
STFYSILPTGKITKVCFAEQTPQVLRFFLLGNKNNTKLLLAIFYHELQSPYVFLGEHFIS
PTPMQPISSLLNESVGANYFDIMDNLLYVVLQGEEPIEIRSAISIHLALTVLFSALEKGW
ELLILERLTDFLQVSQYQIRFIQELPGNKATLQAIADSKAKRKRNCPTVTCSGY--HGLG
QRRHLMMDMSS-YRVSPPNTTESISKVIIIEIGDLPAGRKTGLISSLSMDKLQIFAQQII
TAQQTGMLDNVLNMTIGALLV-TQSKGVTS---NGXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XCT-QAETQ
DGYVSFSDLAVLISGSNWHFIFTVTSPP-EANFTVRSKPFAVSPVMKTEKTTVVLAVSLC
SGVSWLALCCLVCCWLKRNRS--RKIKNEEVSEFLTNDQKN----H-T---SSK------
QESQVD-TEKEDTKMTEDMKMAVMLG-RL-HQAPHQ-TLNGVSRRKVSRRAVQEEG----
-HNPAEAAVSAPRIPSVPSHAH-THAPNSAEQRVHLQESGDWKKAQEQLLRYQLAG--QD
QRLP-LRPDFRQEVKQVQ-ELRQLGEKNGNLGISQETKPSNGATK-------HPETLEQL
--------------------------

-------MPAWLISLMSIEVLLLAVPHLTLHIEPEEGSLAGGTWITVIFDGLE---SGIL
YPNNGSQLEIYLVNASIVVSALLSIPCDVFPVF--LDFPVVTCRTRSLR--SEAHEGLYS
LEAYFGGQLISSPSPGLRDRCTFKFSKAQTPIVHQVYPSSGVPGKLIHVYGWIITGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNRGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDSSAQVTIAGIPCDIRHV--SSRKIECTTRAPGKNARLTSPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFSARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTTDWFDSWEQNR---EEGTWQQKTPKL
ELLGGAKYYLEAEHHGLAPSTGMRIGVQIHNTWLNPDVVTTYLREKHQIRAQAQRLPEVQ
VLNVSG-RGSFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLSANILLRLGFE
RGP-EVSSSDGDLTSGTEPFCGRFSLRQPRHIVLTPSAAQKGYRLDQYTQLCLAYKGHTN
KILKMTVSFTIGFQNMV-KNTTCDWSL----MRTSPKSWQFRCTDLWETCVRCSGDLQPP
LANSPVLVHQIDLLPLA---QETGLFYVDEIIIADTNLTVSQADSGTARPGGNLVESVSV
AGSPPVYSVTSWLAGCGTELPLITARSVPTEGIEQ---------GSGLALVTTQRRQRTS
PPLGGHFRIQLPN-TVISDVPVHISAHHLHQLLQNNADDFTSRYLNASDFTVKEDVNTCY
EHVWTLSWSTQTGDLPNFIR---VSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDIPAYCSGSCSFQYLQGSTPWVHSVWYSIDGDI---NLMVYITGTGFSGD
SQYLELTVNKTNCKVIFSNQTNVVCQIDLLPVGVHRILMLVR PSGLAVNATG-EDLFLNV
E PRLDA-VEPSTAAETGGLWATIRGSSLEGVSLVLFGSYSCAINVTISNSSRIQCKVPPR
GKDG-HIVNVTVIRGDYSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAL-
-LVNYTDLDVEVHIQDALAPVHTQAAWGLEVALPPLPAGLHRISVSINGVSIRSQGVD LH
IRYITEVF SIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLMEASIWCET
PPAPQMPH-AGTPT--VPAAVEVWVG NRSFTSGPSPSLVGNSFTFTYEAAATPLVTALQA
EITNSSVRLCVGGSNLSNSVILLGRLNCDVNTQSF------------QSNASLSGCSIPL
HSLEADIYPLQVRHKQMGFANMSAVPQQFAMT PRIMAIVPSQGSACGGTILTVRGL-LFN
SRRRSVRVDLS--GPFTCVILRLGDRTILCQVTLAGDPLPG-----ASFTL----NVTVL
VNGLTSECQGNCT FFVQEEASPVMDA LTTNTSGSLTTVLMRGQRLGTTADELMVFVDDQL
PCNVTFLNAS-HVACQMRDLAPGLHYLSVFYARNG YACTGNVSRHFYIMPQVF HYFPKNF
SIHGGGLLTIEGTGLRGQNTTSVHIDQQTCLMVNI-SAELIQCIVPTGNGSVALEIEVD G
LLYHIGVVGYSNAFTPELLSISQRDD-ILTFAVAQISGAANIDIFVGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRAYDYIRGWASSVQVFTSRVIITAVTENFG-CLSGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLTFLCDVKHEEDSCEAARHTY
VQCDFTVAVGTEQLLKSWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECEMPNQPITVKITEIRKRWGQNTQGNFPLQFCRRWSRTH
S WFPERLPQDGDNVTVENGRWLLLDTNTSIL-NLLHVKGGKLIFLAPGPIELRAHAILVS
DGGELRIGSKDKPFQGRAQITLYGSPHSIPFFPYGVKFLAVRNGTLSLHGSLPKVIVTH L
RVAAHARDTVLALEDAVDWHPGDEAVIISGTSVEGARPVEEIVIVETVQDTDLYLKSPLR
YSYNLTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGHLQHCLY
SMSEKTLGSRYMGARVIVQSFPEEPSRVQLKGVQLRVLGQAFHKHLSSLILVGT--MRES
FIQGCTVWNSF-SRG LSMCRTLGLKVDSNVFYNILGHALLVGTCMEMRHI-----SWEAI
GGRKD--DWSGHGNTIRNNIIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCAAGY
GYFFHLVTSQTSRAPLLSFTQNIAHSCTRCGLFVYPKFQPPWNNVTGTTLFQNFTVWESA
GGAQI-FRSSNLHLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSGCSRGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCSVNASFGRVVHGSACGGGVLFHRMS
IGLANTPEVSCDLTMTDSRNKTTTVNYVRDTLSNPYGWMALLLDQETYSLHFE-DLWIN-
RSLQYSATFDNFAPGNYLWLVHTD-LPPYP---DILLKCGSRVGLSLPFLPSPAQNQGCD
WFFSSQLRQLTYLVSGEGRVQVILQVKEGM-PPTISASTSAPDSALKWSLPETWQGVEEG
WGG--HNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLEKPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYP
KNSWTHLGADIASGNERLILEDAVDWRPHDKIVLSSSSYEPHETEVLTVKEVKGHYVRIH
ERLKHRHIGSVHVMEDGRHIHLAAEVGLLTRNIQIQPDVSCRGRLLVGSFRKSSREEFSG
VLQLLN---VEIQNFGSSLYSSVEFSNVSTGSWIISSTLHQSCGGGIHAVASHGVRLNDN
IVFGTAGHGIDLEGEAYSLANNLVVLMTQPAWSNIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGYKCSSCEVLWSDNVAHSSLHGLHLYKESGLNNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKNVQIVLRNSVIVATSSSFDCLQDKAKP
HSANLTSSDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYNDDLDVCILPNAENTGIMHPITAERTTMLKMKDKNKFYFSPLQP-RKDFGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
RFLIQGFICKQTDQVVLVLDSADATWANKKLYPVVSVTSGFVDIFSSVNANFPCSTSGSV
STFYSILPTRQITKVCFMDHTPQVLRFFLLGNKSTSKLLLAIFYHELQSPHVFLGESFIP
PTLVQSTSLLLNESTGANYFSIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EMVMLERLSNFLQIGHNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVS
QRRPLMMEMNS-YRVSPPTTVETISKVIVIEIGDLPTVRSNGMISSLSSNKLQNLAHQVI
TAQQTGILENVLNMPIGALLV-TQSKGVTG---YGNTSSFKTGNLIYIRPYALSVLVQPS
NGEVGNELPVQPQLVFLDQQNRRVESLGPPSEPWTISASLEGASDSALK--GCT-QAETQ
DGYVSFYNLAVLISGSNWQFIFTVTSPP-GVNFTARSKPFAILPVTRKEKSTIILAASLS
SVVSWLALSCLVCCWLKRSK--SRKTKPKEIPESQTNNQNN----H-IHISSKC------
QESQ-G-SKKEDTVMGEDMRMKAMLG-RM-NQCPDQ-LMNRVSRRKVSC-----RI----
-VQEEGAALPAPATTSITSHGH-TCTPGAPARPVYLQETGNWKEAQEQLLRYQLAG--QD
QLLL-LCPDLRQERQHLP-GQSWLSKKSGNLGLSLEKKASCGATEAFCLHSVHPGTIQEQ
L-------------------------

-------MTGSLISLTSIQILLLAVSCLNIHIEPEEGSLAGGTWITVIFDGLE---LGLL
HPANGSQLEIHLVN--VALPTLPSIPCDVSPVF--LDVPAVMCRTRSLL--PEAQEGVYS
LEVQAGGQVVGSPHPGPQDSCTFKFSRAQTPIVYQVNPPSGVPGKLIHVYGWIITGRPET
FDFDAEYVDSPLILEA---------QGDKWITPCSLVNRQTGSRYPIQEDHGLGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SVIHKD-AWLVSAKQD----LFLYQTYSEILSVFPETGS
LGGRTDITITGDFFDNPAQVTIAGIPCDIRHV--SPRRIECTTRAP SKGARLSAPQAGNR
GLLFEVGDASEDLDLTEATPGYSWQITPNASSPSGFWSKEG QPFRARLSGFFVAPETNNY
TFWIQADSQASLYFSWSEDLRTKV-KMASIRVGTADWFDSWEQNG---SDKTQQQKTPKL
ELRGGARYYLEAEHRGTAPSSGV RIGVQIHNTWLNADVVSTYLREKHQIRAWAQRLPEIQ
MLTVSG-TGNFFLTWDNVSSQPIPANATAHQIQTVIEELLAVKCKLEPLAANILFWQGFE
QGL-EGSTSDGHLTSGTEPFCGRFSLHQPRHLVLTPPAAQKVYRLDQYTHLCLAYRGQEN
TTLKMTVSFAVGLQNPV-KNLTCDWSL----LGTSP-SWQFTCTDLWKTCVRRSSHLQLP
PANSPVLVHQIDLLPLS---PEMGMFYMDEIIIADTNLTVSQADTGTARPGGNLLESLSV
VGSPPVYNVTSWLAGCGLELPLITASAVPTEGAEE---------GSGLVQVTTRRLQRTS
PPLGGHFRIQLSN-TAIPGIPVHISASHLQKLLQTSADDFTSRYLNVSDFTVTEDLKSCY
EHVWTFSWSSQVGDLPNFIK---VSNENLTGVNPAVITRVVYDGGVFLGPIFGDMLVTAN
QYTQVVVRVNDIPAYCSGSCAFQYLEGSTPQVYSVWYAL-DAV---GLLVYITGTSFSGD
YEALQVTVNKTSCKVIFSNQTNVVCQTSLLPVGVHQILMLVR PSGLAINASG-GGLFLNV
E PRLDA-VEPSRAADIGGLWATVRGSGLDNVNLVLFGSQSGVINVTTSSSQRIQCKVPSK
GEDG-PTVNVTVILGGRSVVLAMAFTYVSSLNPVIVSLSRNGSGIA--GGEILSIGMVL-
-PVNHTDLDAEVCVGDTRAWVQAQTAQGLEVVLPPLPAGLHGISVSINGVHIHFLVLK--
--YLLLSFFLN---ICASGGTILSISGRGFSRDRALLWVLVGSRSCDIVNSTETSVWCET
PPPAP-----LPLS--APVPVEVWAG SKPFPHRPSPRLVGKGFTFMYEVAATPVVTVMRG
EVTNHSLRLYVEGRNLSDSVVLLGNLSCDLQTPSP------------GSNLSLAGCAFPL
DTLEAGVYPLQVHQRQMGFADMSAVPQQWVVM PQITAVFPTRGSTCGGTVLTVRGL-ALR
SSRGSVEVDLS--GPFTCVILSFGDQTVFCRITPMGDPLPG-----ASFTL----NVTVL
VNGL PSMCQGNCTLFLCEETTPIMDDWT TNISGSLTTVLVRGQRLGITADEPVVFVDDRL
ACTVTFHNAS-HVACWISDLSPGPHYLSVLHARYGYACS GNFSRHFHVWPQVFH YFPKNF
SLHGGSLLTLEGTALKGLNSTLVYIGQQACLTVSL-GSELIQCAVPAGNGSAALGIE IDG
ASYQMGVIGYSSAFTPELLSVSQTDD-VLTFSVARISGAANVDIFIGTSPCVGVSG----
NHTLLHCVVPSLPTGEYQVRGYDRMRGWASSVLVFTSRVTVTAVTENFG-RLGGRLVHVF
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDVSLASLCDLRPEEEDCETSSCSY
VHCDLTITVGTDSLPESWPYFYICEESSRCLLARDHWTE---STLPS-FSGLFISPKVER
DEVLIYNSSCTITMETEAKMECETPNQPITAKITEIRKSRGQNTQGNFIFQFCGRWSRAH
S WFPKRPPQEGDNVTVEKGQLLLLDTNTSIL-NFLHVKGGKLIFLDLGPLELRTHSILVS
DGGELRIGSEDKPFQGKARIKLYGSSYSARFFPYGVKFLAVRNGTLSLHGSLPEVVVTH L
RAAANAHDTVLALEDAVDWHAGDEVLVISGMGAEGAKPKEEIVTVETAHSTDLQLRSPLR
YSHNSTENWVAGEHHVLKVMLVLLSRSITIQGNLTDERVQFLASCQGASASEGDLQNCLY
SKSEKMLGSRDLGARVIVQSFPEEPSRVQLKGVQFRDLGQAFREHVSSLVLIGA--MRGE
EVQACCLIFLLLCSRLSMQ----------------------GGPGRWYVG-----TWGIY
GSKSHLENW SEQGNVIRNNVIIRVSGAEGLSSPEVVTPSGIYIRHPTNVIEGNRVFAAGY
GYFFHLVTNKTSQAPLLSFTRNSAHSCTRSGLFVYPKFQPPWDNSTGSTLFQNFTVWGSA
GGAQI-FRSSNLHLKNF QVYACRDFGIDVLESDANTSITDSLLLGHFAHR---GNLCMSA
GIKSPRRWELRVSNTTFVNFDLTHCVAIRTCSGCSQGQGGFTVKTNQL--KFVNSPNLVA
FPSPHAAILEDLDGSLSGKNRSHILASMETLPASCVVKASFSQLVHGSVCEENVLFHRMS
IGLANALNVSHDLTITDSRNKTTTVSYVHDTLSNPYGWMALLLDQETYSLRFE-SPWAS-
SALQYSATFDNFAPGNYLLLVHTD-VWVYP---DILIRCGSHVGRSLSSLPSPGQDQGCD
WFFDSQLRQLTYLVSGEGQVKVALQVRKGV-GPTISASAPVPKSVLKWSLPETWEGVAEG
WGG--HNGASPGPGEDVLILSNRTVLVDTDLPPLRGLYVMGTLEFPVDRSNILSVACMLI
AGGELRV--GTSENPLEKEKKLLIHLRASEGVFCDRFNGIHIDPGTVGVFGKVQLHSAYP
KKSWTR LGADIASGNERIIVEDTVDWRPHDKIVLSSSSYEPHEAEVLTVKEVRGHHIRIR
ERLRHRHIGSAHFMEGGRHIRLAAEVGLLTRNIQIQGDTPCRGRLLVGSFRKSSVEEFSG
ILQLFN---VEIQNFGSPLYSSVELTNVSA GSWIISSSLHQSCGGGIHAAASQGVILNDN
VVFSTAGHGIDLEGQDYSLSKNLVVLMTQSAWSPVWVAGIKVNEAKNTHLHGNVVAGSER
LGFHIQGHRCSSPESLWSDNVAHSSLHGLHLYKGSGLVNCTGISGFLAFKNFDYGAMLQV
ENSMEIENLTLVDNTVGLFTAVYVSSAPRCYIRNLQIVLRNSVIVATSSSFDCIQDRVKP
HSANLTSPDRAPSNPKGGRVGMLWPVFTSEPNRWPQEPWHKV-RNGHLISGIMKLQ-DVI
FSSFVKSCYSDDLDVCILPNAQNTGIVPPIMAERTSMLKIKDKNKFYFPPLQT-RKDLET
LVCSESDCKSPGKYLFKDLDGRALGLPPPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
RPLINGYICKQTDQVILILDSADTTWAMQKLYPVVSVTSGFVDTFSSINASAPCSISRSV
SAFYSIVPTRKITKVCFVDQTPRVLHFFLLGNKNTSKLLLAVFYHELQSPYVFLGDRFIP
PTQVHSTSSLLNESIGSNYFSITDNLLYVVLQGEEPIEIQSSVSIHLALNVMFSVLEKGW
EIVILERLTVFLQISQDQIRFIHQMPGNEATLKAMADSRAKRKRNCPTVTCTSH-D-RVG
QRRPLMVEMSS-YRDLPPTTMETISKVMVIEIGDLPTVRNAGLIPSLSSNKLQNLAHQVI
IAQQTGLLESVLNMTIGALLV-TQSKGVIG---YGNTSSFKTGNFIYIRPCSLSVLIQPS
DGEVGKELTIQPQLVFLDKQNRRVESLGPPSEPWVISVSLEGTLDSVLR--GCT-HAETQ
DGYVSFSNLAVLISGSNWHFIFTVISPP-GVNFTARSRSFAVLPVTPSERPTIIMAASLC
SGVSWLALCCLICCWFKKSKT--RKIKNEEISETQTNDQRN----H-SHVSPKH------
QGSQVE-TEKEVTRMAEDLRMKVMLA-KL-NQLPHQ-SLNGVSRRKVSHRVVREE-----
-----EAAVPAPSIASVTSHRN-TCTPGSPAQHGCLQESGDWKGAQEQVLRYQLAG--QD
QLLL-LCPDLRRERQRLQ-GQSQLGKGHISLGLSQEKPGSCGATEAFCLHSVHPEAVQEQ
L-------------------------

-------MTAWLISLMSIEVLLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGAL
YPNNGSQLEIYLVNVSMVVPALPSIPCDVFPVF--LDFPVVTCRTRSLL--SEAHEGLYS
LEAYFGGQLISSPCPGLRERCTFKFSKAQTPIVHQVYPSSGVPGKLIHVYGWIITGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPVQEDHGLGTLQCHV
EGNY-IGSQNVSFSVFNRGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDSSAQVTIAGIPCDIRHV--SSRKIECTTRAPGKNARLTSPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWPKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KLASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSMGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLSANILLRLGFE
QGP-EVSSSDGDLTSGTEPFCGRFSLRQPRHLVLTPSAAQKGYRLDQYTHLCLAYKGHTN
KILKMTVSFTIGFQNMV-KNTTCDWSL----MRTSPKSWQFRCTDLWETCVRCSGDLQPP
LANSPVLVHQIDLLPLA---QETGLFYVDEIIIADTNLTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPAEGTEQ---------GSELVLVTTQRRQQMS
PPLGGHFRIQLPN-TVISDVPVHVSARHLHQLLQNNADDFTSRYLNASDFTVKKDVNSCY
EHVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATAN
QHSQVIVRVNDVPAYCSGSCSFQYLQASTPWVHSVWYSIDGDI---NLMVSITGTGFSGD
SQFLEVTVNKTNCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDA-VEPSRAAETGGLWATIRGSSLEGVSLVLFGSYSCAINVTISNSSRIQCKVPPR
GKDG-HIVNVTVIRGDYSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAL-
-LVNYTDLDVEVHIQDALAPVHTQAAWGLEVTLPPLPAGLHRISVSINGVSIRSQGVD LH
IQYITEVF SIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLMEASIWCET
PPAPQMPH-AGTPT--VPAAVEVWAGNRSFTLGPSPSLVGNSFTFMYEAASTPLVTALQA
EITNSSLHLHVGGSNLSNSVILLGRLNCDVDTQSF------------QSNASLSGCSIPL
HSLEADIYPLQVRHKQMGFANMSAVPQQFAVM PRITAIVPSQGSACGGTILTVRGL-LLN
SRRRSVRVDLS--GPFTCVILSLGDRTILCQVSLEGDPLPG-----ASFTL----NVTVL
VNGLTSECQGNCT FFMQEEASPVMDA LTTNTSGSLTTVLMRGQRLGTTADELMVFVDDQL
PCNVTFFNAS-HVACQMRDLAPGLHYLSVFYARNG YACTGNVSRHFYITPQVF HYFPKNF
SIHGGGLLTIEGTGLRGQNTTSVYLDQQACLMVNI-SAELIRCIVPTGNGSVALEIEVD G
LLYHIGVIGYSNAFTPELLSISQRDD-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRAYDYIRGWASSVQAFTSRVIITAVTKNFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVPPLDVSLTFLCGVKHEEDSCEAARHTY
VQCDLTVAVGTERLLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGFFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFPLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSIL-NLLHVKGGKLIFLAPGPIELRAHAILVS
DGGELRIGSKDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPKVIVTH L
RATARARDTVLALEDAVDWHPGDEVVIISGTSVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGHMQHCLY
SMSEKTLGSRDMGARVIVQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLILVGT--MRES
FIQGCTVWNSF-SR GLSMCRTSGLNVDSNLFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKD--DWSGHGNIIRNNIIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCAAGY
GYFFHLVTSQTSRAPLLSFTQNIAHSCTRCGLFVYPKFQPPWNNVTGTTLFQNFTVWESA
GGAQI-FRSSNLHLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTIFVNFDLINCVAIRTCSGCSRGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRAVHGSACGGDVLFHRMS
IGLANAPEVSCDLTMTDSRNKTTTVNYVHDTLSNPYGWMALLLDQETYSLHFE-NLWIN-
RSLQYSATFDNFASGNYLWLVHTD-LPPYP---DILLKCGSRVGLSFPFLPSPAQNQGCD
WFFNSQLRQLTYLVSGEGRVQVILQVKEGM-PPTISASTSAPDSALKWSLPETWQGVEEG
WGG--YNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGFHIDPGTIGVYGKVQLYSAYP
KNSWTH LGADIASGNERLILEDAVDWRPHDKIVLTSSSYEPHETEVLTVKEVKGHYVRIN
ERLKHRHIGSVHVMEDGRHIHLAAEVGLLTRNIQIQPDISCKGRLLVGSFRKSSQEEFSG
VLQLLN---VEIRNFGSSLYSSVEFSNV STGSWIISSTLHQSCGGGIHAAASHGVRLNDN
IVFGTVGHGIDLEGQAYSLTNNLVVLMTQPAWSNIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGYKCSSCEVLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKNVQIVLRNSVIVATSSSFDCLQDKVKP
HSANLTSSDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDRSISGIMKLQ-DVT
FSGFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKMKDKNKFYFSPLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
QFLMQGFICKQTDQVVLVLDNADATWANQKLYPVVSVTSGFVDIFSSVNANFPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTLVQSTSLLLNESTGANYFSIMDNLLYVVLQGEEPVEIHSGVSIHLALTVMVSVLEKGW
EIVILERLSNFLQIGHNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVS
QRRPLMMEMNS-YRVSQPTTVETISKLIVIEIGDLPTVRSNGMISSLSSNKLQNLADQVI
TAQQTGILENVLNMPIGALLV-TQSKGVIG---YGNTSSFKTGNLIYIRPYALSVLVQPS
DGEVGNKLPVQPQLVFLDKQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVNFYNLAVLISGSNWHFIFTVTSPP-GVNFTTRSKPFAILPMTRKEKSTIILAASLS
SVVSWLALSCLVCCWLKRSK--SRKMKPEEIPESQTNNQNN----H-IHISSKC------
QESQ-G-TKKEDTVVGEDMRMKAMLG-RL-NQCPHQ-LMNGVSRRKVSR-----HN----
-VQEEGAALPAPATTSITSHGH-TCAPGAPARPVYLQETGNWKEAQEQLLRYQLAG--QD
QLLL-LCPDLRQERQHLP-GQSQLSKKSGNLGLSQEKKASCGATEAFCLHSVHPGTIQEQ
L-------------------------

-------MTGWLISLMSAEILLLAVSSLRFHIEPEEGSLAGGTWITVLFDDLY---LELL
YPTNGSQLEIHLVN--VAVPGLPSIPCDVSPVF--LDLPLVMCRTRSLL--SEAHEGLYY
LEVHSGGQVVGSPSPGPQDNCTFQFSRGQTPIVYHVIPPSGVPGELIHVYGWIITGRPET
FDCDAEYIDSPLILEA---------QGDNWVTACSLVNRQTGSCYPLQEDHGFGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SMVHKN-AWLVSAKQE----LFLYQTYSEILSVFPESGS
LGGKTDIIITGDFFDNPARVTIAGIPCDIRHV--SPRKIECTTR APGKGARLTAPQAGNR
GLLFEVGDAAEGLDLTAATSGYWWQIVPNASSPFGFWSKEG QPFRARLSGFFVAPETNNY
TFWVQADDQASLYLSQSEDPRTKV-KVASISVGTADWFDAWEHHG---NEGTWQRKTPKL
ELVGGTRYYLEAEHYGRVPRRG MRIGVQIHNTWLNPAVVSTYLREKHQIRIRAQRLPEIQ
MLTLSG-RRNFFLTWDNVFSQPVPENATAHQIQVAIEKLLAVKCQLEPLSANILLWLGFE
QGP-EGSSFEGDLTSATEPYCGRFSLHQPRHLVLTPPAAQKGYRLDRYTHLCIAYRGHTT
NILKVTMVFTTDFQNFVKKNATCDWSL----VGTSPNSWQFTCIDLWESCVHHPEYSQLP
LENSSVLVYQIDLLPLS---QETSGFYVDEIIIADTNVTVSQADSGTACPGGNLVESLSV
VGSPPVYNVSFWLAGCGQELPLITASSLPTEGEEE---------EPRLVQVTTQRIQRAS
PPLGGYFRIQLPT-TVIPDVPVSISASHLRKLLQNNADNFTSRYLNVSDFTVMEDLKSCY
ERVWTLSWSNQVGDLPNFIR---VSDENLTGVNPEATMRVVYDGGVFLGPIFGDMLVTAN
QCTQVVVHVNDIPAHCSGSCSFQYLEGSTPQVHSVWYSLDGDK---DLLVYIFGTSFSID
PQALDVTVNKTNCRVIFSNQTNVVCQTQQLPVGMHPISMLVR PSGRAINASG-EGLFLHV
E PRLDA-VEPSRAAEIGGLWATVQGSGLEDVSLVLFGSQSCAINITTNNSRRIQCKVPPR
GKDG-PIVNVTVIRGDHSAVLPMAFTYVSSLNPVIISLSRNTSSIA--GGETLFIGMAL-
-LVNYTDLDVEVCIQDTVALVHVQMARGLEVVLPPLPVSLHRISVSINGISIRSQGVDLH
IRYITEVFSMEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNSTESIIWCET
PPAALLPD-AGVPA--LPAPVEVWAG NVSFAQGPSPSLVGKGFTFMYEAGATPVVTAMRG
EITNSSLRLYVEGNNLSNSVILLGVLNCDLETQFL------------RNNMSLSGCSFPL
HHLEAGIYPFQVRQKQMGFANMSAVPQQFVMT PRITAIWPTHGSACGGTILTVRGL-ALK
SRNRSVHVDLS--GPFTCVILSLWDQTVLCQINRVGDPLPD-----ASFTL----NITVL
VNGLPSECQGNCT FFFQEETTPIVDALT TDISGSLTMVLIRGQKLGITADEPMVFVDNHL
PCVVTFFNAS-HVSCWISDLTPGLHYVSVVHTRNGY ACFGNVSRHFYILPQVF HYFPKNF
SIHGGSLLTMKGTALRGENSTLVYIGQQACLTVSI-STKLIQCVVPAGNGSVALVIEVDG
LSYQ MGAIGYSNAFTPELLSMSQADD-ILTFVVAQISGAANVDIFIGMSPCVGVSG----
NRTVLQCVVTSLPAGKYPVRGYDRSRGWASSVLVFTSTVTILAVTENFG-CLGGSLVHVF
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDVSLAFLCGLKHEEESCEASSCTY
VQCDLTVTVGTERLPQSWPYLYVCEEGPQCLLAPDHWTE---STFPW-FSGLFISPKVER
DEVLIYNSSCNITMETEAKMECETPNQPITAKITEIRKSRGQNTQGNFSFQFCLRWSRAY
S WFPERVPQDGDNVTVENGQLLLLDTNTSIL-SFLHVKGGKLIFMDPGPIELRVHSILIS
DGGELRIGSKDKPFQGKAEIKLYGSSHSTPFFPYGVKFLAVRSGTLSLHGSLPEVTVTH L
RAAAYASDKVLALEDAVDWHSGDEVVIISGIGVKGAKPIEEMVIVDTVHTTDLYLRSPLR
YSHNFTESWVAGGRHILKVTVALLSRSVTIRGNLTTERMKHLASCQEASGSEGNLQDCLY
SKSEKMLGSRDLGARVIVQSFPEEPSRVQLKGVQFRDLGQAFHRQLSSLTLVGA--LRDS
YIQGCTVWSSF-SR GLSMSRTLGLKVDSNTFYNILGHALLVGTDMDRRYT-----SWEAT
YERKI--AWPVQGNIIRNNVIISVSGTEGLSSPEMLTPSGIYIRNPTNVVEGNRVYVAGL
GYFFHLVTSQASQSPLLSFSQNIAHSCTRCGLFVYPQFQPPWDNGKGLTVFQNFTVWGSA
GGAQI-FRSSNLHLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---ESQCMSA
GIKTPKRRELIISNTTFVNFDLTDCVSIRTCSGCSQGQGGFPVKTDQL--KFINSPNLVA
FPFPYSAILEDMDGSLSGRNRSHILASMETLPASCLVNTSFSQIVHGSVCGEDVHFHRMS
IGLANAPDVPYDLIMTDSRNKTTIVNYVHDTLSNPYGWMALLLDQETYSVQFE-NPWIN-
RSLQYSATFGNFAPGNYLLLMHTV-SWPYP---DILIRCGSRVGQSLPSLPSPGQDQGCD
WFFNTQLRQLTYLVSGEGQVQVTLQVKEGV-PPTISASTSAPKSALKWSLPEAWIGLEEG
WGG--HNHTIPGPGDDVLILPNRTVLVDMNLPFLKGLYVMGTLEFPVDRSNVLSVACMVI
VGGELKV--GTLENPLGKEQKLLILLRASEGVFCDRFNGIHVDPGTIGVYGKVQLHGACP
KKSWTRL AADIAPGNERIIVEDTVDWQPHDKIILSSSSYEPHEAEVLTVKEVKAHHIRIY
ERLKHRHIGSVHVMEDGRYIRLAAEVGLLTRNIQIQPDSSCRARLLVGSFRKSNSEEFSG
VLQLSN---VEIQNFGSSLYSSIELTNA SEGSWIISSTLHQSCGGGIRAAASHGIVLNDN
VVFGTVGHGIDLEGQNFSLSNNLLVLMTQSSWSTVWVAGIKVNQAKNINLFGNVVAGSER
LGFHIRGYRCSSPEARWSDNVAHSSLHGLHLYKENGLDNCTCISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNAIGLLATVYMSYAPQRHIENLQIVLRNSVIVATSSSFDCIQDRVKP
RAANVTSTDRAPSNPRGGRVGILWPVFTSEPNQWPQEPWHRV-RNDHSISGIMKIQ-DVT
FSSFVKSCYNDDLDVCILPNVENTGIVHPITAERTRMLNIKDNNKFYFPPLQT-RKSLGM
LVCPESDCEDPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
QPFIQGYICKQTDQVILILDNADATWTMQKLYPVVSVTNGFVDTFSSVNANTPCSTLGSV
SSFYSILPIREITKVCFVDQTPQILRFLLSGNKNTSKLLLAIFYHELQSPRVFIGKSFIP
PVLVQSTSSLLDESSGSNYFSILDNLLYVVLQGQEPIEIRSGVSIHLAFTVIFPVLEKGW
EILILERLTDFLQVSQNQIRFIHEMPGSEATLKAIADNKAKRKLNCPTVTCASH-Y-RVG
QRRPLMMETSS-YRILPPTTMETISKVVVIEIGDLATIRSTGLISSLSSKKLQNLAHQII
TAQQTGVLENVLNTTIGALLV-TQSKGITG---YGNTSSFKTRNLIYIRPHALSVLVQPS
DGEVGKELRVQPQLVFLDKQNQRIESLGPPSEPWAISVSLEGTSDSVLK--GCT-QAESQ
DGYVSFSNLAVLISGSNWHFIFTVTSPP-GANFTARSKSFVVSPATMSEKSTIILAVSLC
SVASWLALCCLVCCWFKKSKS--RKIKSGDISEFQTNGQKN----H-IHISSKR------
QGSHVE-TEKEDTMMGEDRKMKVMVD-KL-NQLPHQ-SLNGVSRRKVGHRAVQKEA----
-GRQEEAVAPALGLTSVPSQGH-TCAPGSLAQHVYLQETGNWREAQEQLVRYQLAG--QD
QQLL-LCPDFRQERQQLQ-GQSQLGKERVSVGLSQEKRDSCGATQAFSLHSVHPETIQEQ
L-------------------------

-------MIAWLISLRSIEIILLAMPCQSFHIEPEEGSIAGGTWITVIFDDLE---SSLL
YPTNGSQLEIHLVN--VAVPALPSIPCDVSPVF--LDLPVVMCKTRSLL--SQVHEGMYH
LEVHSGGQVAGSPTAGLPDSCSFKFSRAQTPIVYQVSPPSGVPGQLIHVHGWIITGQLET
FDFNAEYIDSPLILEA---------QGDYWVTPCSLVNRQTGSCYPLQEDHGLGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SMVHKN-AWLISAKQD----LFLYQTYSEILSVFPETGS
LGGKTDITITGDFFDIPAQVTIAGIPCDVRHV--SPRRIACTTRAPGEGARLTAPQAGNR
GLLFEVGDAAEGLDLTEATPGYRRQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSRSEDPRTKV-KVASIRLGTADWFDSWENGN---DEGTWQRKSPKL
ELLGGARYYLEAEQRGRAPSGGMRIGVQIHNTWLNPDVVSTYLREKHQIRIRAGRLPEIQ
MLTVSG-SGSFFLTWDNVSSQPIPANATAHQIQTAIEELLAVKCQLEPFSANILLRVGFE
QGP-EGSSFDGDLTSGTEPFCGRFSLCRPRHLVLTPPAAQHGYRLDQYTQLCIAYKGHMN
KTLKVTVSFTIDLQNII-KNITCDWSL----IGTSPESWRFTCTNLWKTCVHRSTHLQRP
LANSPVLVHRIDLFPLA---LETGLFCVDEVIIADTNLTVSQADSGTARPGGNLVESLSV
VGSSPVYNVTSWLAGCVSELPLITASAVPTEGAEE---------GSGLVQVATQRLQRTS
PPLGGHFCIHLSN-TVIPDVPVRISASHLRKLLQNNADDVTSRYLNVSDFTVKEDLKSCY
EHVWTLSWSTQVGDLPNFIQ---VSDENLTGVNPAATTRVVYDGGVFLAPIFGDMLVTAN
QHTQVVVQVNDILAHCSGSCSFQYLEGSTPRVHSVWYSLDGDM---DLLVYITGTSFSED
SQALQITVNKTSCKVIFSNQTDVVCQADLLPVGVYQISVLVRPLGRAINASG-GGLFLNV
EPRLDA-VEPPRAAEIGGLWATVRGSGLEDVSLVLFGSQSCAINVTTSNSRRIQCQVPPR
GKDG-SIVNVTVIRGDHSAVLSMAFT YVPSLN PVIMSLSRNKSNIA--GGETLFISVAL-
-PVDYLDLRVEVHIQDSLAQVHAETAQGLEVVLPPLPAGLHRISVSINGVSIRAQGVDLH
IQYI TEVFSIEPCCGSLLGGTILTIAGAGFSRDPALIWVLVGNRSCDIVNLTETNIWCET
-PTVLPPE-ADVLT--VPAPVEVWTGNRSFTQAPGPHL VGKGFTFTYAVATTPVVTAVRG
EFTNSSLSLYVEGNNLSNSVMLLGDLNCDLETQSF------------GNNVSLSGCSFPL
HGLEAGAYPLQVRHKQMGFANMSAVPQQFVVT PQIMAISPAKGSACGGTVLTVSGL-ALN
SRRKLVQVDLS--GPVTCATLSLGDQTILCQVDLLGDSLSG-----ASFTL----NVSVL
VNGLPSECQGNCTLS LREETT PVVDALTTNISGSLTSVLIRGQRLGTTADEPVVYLDDHL
PCIVTFFNAS-HITCWISDLSPGLHYLSVVHSRNGYACSGNVSRH FSIL PQVLDYFPKNF
STHGGGLLTLEGTALRGLNCTLVYIGQRACLTVTI-SAELIRCIVPAGNGSAVLDIEVDG
RSYQMGVIDYSSTFTPELLSVSHTGD-VLTFVVARISGAENVDIFIGVSPCVGVSG----
NCTVLQCVVPVLAAGEYQVRGYDHIRGWASSVLVFTSRVTVTAVAESFG-CLGGRLVHVF
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDVSLASLCDLKHEQESCEAASHTY
VQCDLTVTVGAERLPESWPYLYICEESSQC-----HWTE---SAFPL-FSGLFVSPKVER
DEVLIYNSSCNITMETEAKMECETPNQPITAKITEIRKSRGQNTQGNVSFHFCRRWSRAY
SWFPERAPQDGDNVTVENGQLLLLDTNTSIL-NFLHVKGGKLIFMDQGTIELRAHSILVS
DGGELRIGSEDKPFQGQAEITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTHL
RAAASARDTVLALEDAVDWHSGDEVVIISGMGVEGARPMEEIVVVETVHNADLYLRSPLR
YSHNFTENWVAGEHHILKATVALLSRRIIIQGNLTSERTKFLASCQEANTSEGNLQHCLY
SKSEKMLGSRDLGARIIIQSVPEEPSRVQLQGVQFRNLGQAFQKHLSSLTLVGA--MRDS
YIQGCTVWGSF-SRGLSMSGTLGLKVDSNVFYDILGHALLVGTHVETRYI-----PWEAI
PGRKN--DRSEQGNTVRNNVIISVSGAEGLSSPEMLTPSGVYIRNPTNVVEGNTVCDAGF
GYFFHLVTNQTSQAPLLSFTGNIAHSCTRYGLFVYPKFQPPWDNDTGPTLFQNFRVWGSA
GGVQI-FRSSNLHLKNFQVYSCRDFGIDILESDANTLVTDSLFLGHFAHQ---GSLCMSA
GIKTPKRWELMVSNTTFVNFDLTGCVSIRTCSGCSRGQGGFTVKTNQL--KFTNSPNVVA
FPFPHAAILEDVDGSLSGKNGSHILASMETLSDSCSVSARFSQIVPGSVCGEDVFFHRMS
IGLTNAPDISYDLTLTDSRNKTTTVNYVRDTLSNPDGWMALLLDQETYSLRFE-TPWTN-
RSLQYSATFDNFAPGNYLRLVHTV-LWPSP---DILIRCGSRAGRSLPSLPSPGKDQGCD
WFFNSQLRQLTYLVSGEGQVQVIVQVKEGV-PPTISESPKRHEIRLCWSLRESWADLEDG
WGWGTFQNTLPQEGMVVLQLADRTVLVDTDLPFLKGLYVMGTLEFPVDRSNILSVACMVI
AGGELKI--GTLENPLQKEQKLLILLRASEGVFCDRFNGIHIDPGTIGVYGKLQLHSAYP
KKSWTRLGADIASGNERIIVEDAVDWRPHDKIVLGSSSYEPHEAEVLTLKEVKGHHVRIQ
ERLKHRHIGSVHVLEDGPYIRLAAEVGLLTRNIQIQSDTSCRGRLLVGSFRKSSREEFSG
VLQLLN---VEIQNFGSPLSSSIEFTNVSAGSWIISSALHHSCGGGIRAVASHGIILNDN
IVFSTVGHGIDLEGQAYSLSNNLVVLMTQSAWSTVWVAGIKVNQAKDTTLRGNVVAGSER
LGFHIRGQRCSPLEALWSDNVAHSSLHGLHLYKESGLGNCTRISGFLAFKNFDYGAMLHV
ENSMEIENVTLVDNAIGLLAVVYVSSASQPSIENVQIVLRNSVIVATSSSFDCIQDRVKP
GSANWTLMDRAPSNPRGGRVGILWPVFTSEPNRWPQEPWHKV-RNGHSVSGIMKLQ-DVT
FSSFVKSCYSNDLDVCILPNAENTGIIHPITAERTKMLKIKDKNKFYFPPLQT-REDLGT
LVCSESVCENPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
RSLIQGYICKETDQVILILDIVNATWVMRKLYPVVSVTSSFVDTFSGVNANTSCSTSGSV
STFYSILPTRETTKVCFVDQTPHVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PILVQSTSSLLDESVGSNYFSIMDNLLYVVLQGEELVEIRSGVSIHLAFTVLFSVLEKGW
EVVTLERLTEFLQISQDQIRFIYDMPGNEATLKAIADHRAKRKRNCPTVPCTSY-Y-RAG
QRRPLMTEMNS-YRVPLPTTMETMSKVMVIEIGDLPTVRSPGWIPSLSSDKLQNLAHQVI
TAQQTGVLESMLNMTIGALLV-THSEGVIG---YGNTSNFKTGNSIYVRPYALSVLVQPS
DGEVGKELPVQPQLIFLDKQNRRVESLGLPSEPWAISVSLEGTSDSVLK--GCT-QAETR
DGYVSFSNLAILISGSNWHFLFTVTSPP-GTNFTTRSRPFAILPVTRSEKSTIILSASLC
SVVSWLALCCLVCCWFKKSKS--RKIKSEDISASQTNDQKN----H-VHVSSKR------
QGSQVE-TEKEDPIVGE-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

-------MTAWLISLMSIEVLLLAVPHLSLHTEPEEGSLAGGTWITVIFDGLE---LGVL
YPNNGSQLEIHLVNMNMVVPALRSIPCDVFPVF--LDLPVVTCRTRSVL--SEAHEGLYF
LEAYFGGQLVSSPNPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKKSSIKIGII----VN
LFAKACCKPSPVILEA---------QGDKWVTPCSLINRQMGSRYPIQEDHGLGTLQCRV
EGDY-IGLL---------EK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKDVRLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSQEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRLPEVQ
LLTQGC-MGNWV-------------------------------------------RTGVF
LSP-EVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWSL----TRTSPESWQFHCTDIWETCVRCSGDLQPP
PANSPVLVHQIDLLPLA---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVLTEGSPE---------NLIVSV----------
--------FSVSK-PSLTDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDLYTCY
EHVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATAN
QHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDI---NLMIYITGTGFSGD
SQFLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMMVR PSGLAISATG-EDLFLNV
E PRLDM-VEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-RIVNVTVIRGDYSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAR-
-LVNCTDLDVEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIRSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEVSIWCET
LPAPQIPH-AGAPT--VPAVVEVWAGNRSFARGPSPSLVGKGFTFMYEAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSVILLGNLNCDVETQSF------------QGNVSLSGCSIPL
HSLEAGIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGL-LLN
SRRRSVRVDLS--GPFTCVILSLGDHTILCQVILEGDPLPG-----ASFSL----NVTVL
VNGLTS ECQGNCTLFIREEASP VMDALSTNTSGSLTTVLIRGQRLATTADELMVFVDDQL
SCNVTFFNAS-HVVCQTRDLAPGPHYLSVFYTRNGYACSG NVSRNFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYVDQQACLTVNI-GAELIRCIVPTGNGSVALEIEVDG
LWYH IGVIGYNNAFTPELISISQNDD-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKREEDSCEAARHTY
VQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSIL-NLLHIRGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHALDTVLALEDAVDWHPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRNSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
RGRKD--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAGY
GYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWESA
GGAQI-FRSSNLRLKNF KVYSCRDFGIDVLESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAVLEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMS
IGLANTPEVSYDLTMTDSRNKTTTVNYVRDTLSNPHGWMALLLDHETYSLQSE-NLWIN-
RSLRYRHKK-----------------------------------------PSKKINESRS
WFFEKINKIDRLLIF-----------K--N-FFYFLASTSAPESALKWSLPETWQGVEEG
WGG--YNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVQLYSAYP
KNSWTHLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIY
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRVFVGSFRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSAGSWIISSTLHQSCGGGIHAAANHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNIVAGSER
LGFHIRGRKCSSCELLWSDNVVHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSVRKVQIVLRNSVIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENSGIVHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
QFLMQGFICKQTDQVVLILDSADAIWAIQKLYPVVSVTSGFVDVFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVG
QRRPLTMEMNS-HRASPPMTVETISKVIIIEIGDSPTVRSTGMISSLSSNKLQKLAHQVI
TAQQTGVLENVLNMTIGALLV-TQSKGVIG---YGNTSSFKTGNLIYIRPYALSILVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVNFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSKPFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVGCWLKRSK--SRKTKPEEIPESQTNNQNS----H-IHISSKR------
RESQ-G-PKKEDTVVGEDMRMKVMLG-KV-NQCPHQ-LMNGVSRRKVSR-----HF----
-VREEEAAVPAPGTTSITSHGH-ICAPGAPAQQVYLQETGNWKEGQEQFLRYQLAG--QD
QLLL-LCPDFRQERQQLP-GQSRLSKQSGSLGLSQEKKASCGATEAFCLHSVHPETIQEQ
L-------------------------

-------MTVWLISLMSMEILLLAVPSRSFHIEPEEGSLAGGTWITVIFDGLE---SEFL
YPANGAQLEIHLVN--VAEPSLPSIPCDVSPVF--LDLPVVMCRTRSLL--SEAHEGLYY
LEVHSGGQVVGSPSPGPRDNCTFKFSRAQTPIVYQVTPPSGAPGKLIHVYGWIITGRSET
FDFEAEYIESPLIMEA---------QGDKWVTACSLVNRQTGSRYPLQEDHGLGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SIVHKN-AWMISAKLE----LFLYQTHSEILSVFPDTGS
LGGRTDITITGDFFDNPVQVTIAGIPCDIRDV--SPRKIECTTRAPGKSARLTAPQAGNR
GLLFEVGEAVEGLDLTSGMPGYQWQIVPNASSPPGFWSKEGLPFRARLSGFFVAPETNNY
TFWIQADNQASLYFSHSEDPKTKV-KVASIKVGIADWFDAWEQNG---HDGTWQRKTPKL
ELVGGTSYFLEAEHGGRAPSRGMRIGVQIHNTWLNPDVVSTYLREKQQIRIHAQRLPEIQ
MLTVSG-RGSFVLTWDNVTSQPIPGNVTAHQIQRAIEELLAVKCKLEPLSASSLLWLGFE
QGP-EGSSFEGDLTSGTEPFCGRFSLHQPRHLVLIPLASQEGYQLDQYTHLCLAYKGHKN
NILKVTVFFTTDSQNFIKKNITCDWSL----VGTSPDSWRFTCTDLWETCVQGSVDLQPA
LANSSVLVYQIDLFPLS---QETRGFYVDEIIIADTNITVSQADSETARPGGNLVESLCV
EGSPPVYNVSFWLVGCGRELPLITASSVPTEGGQE---------ESGVVQVTTQRIQKTS
PPLGGYFRIQLPT-TEIPDIPVHVSASDLRKLLQNNADNFTSRYLNVNDFAVTEDLRSCY
EHVWTLSWSTQVGDLPNFIR---VSDAHLTGVDPAAAMRVVYDGGVFLGPIFGDMLVTAN
QHTQVVVRVNDIPAHCSGSCSFQYLEESTPQVHLVWYSLDGDI---HLLVYIFGTSFSGD
PQAVQVTVNKTICRVLFSNETNVVCQTDLLPVGMHRLSVVVR PSGCAINASG-EALFLNV
E PRLVA-VEPSRAAEIGGLWATIQGSGLEDVSLVLFGSRSCAIDITRSNSQRIQCKVPPR
GKDG-PIVNLTVITGDHSAVLPMAFT YDSSLN PVIISLSRNRSNIA--GGETLSIRMAL-
-LGNYSDLDVEVHIQDTLVPAHVQMPHSLEVVLPPLPPGLHRISVSINGVSIRS RRVDLH
IQYVTDVF SIEPCCGSLLGGTILTVSGVGFSRDPDLVWVLVGNRTCDIVNSTDTVIWCET
PPSALLPK-ADVPT--VPAPVEVWAG NASLVRGPLPSLVGKGFTFMYEVARTPVVTAVQG
EMTNNSLRLSVEGNNLPNSVILLGFLNCDLEMQSL------------WNNMSLSGCSFPL
HSLEAGTYPLQVRQKQMGFANMSAVPQQFVMT PRIMAILPTRGSACGGTVLTVRGL-ALN
SRKRSVQVHLS--GPFSCVILSLGDQTVLCQISQVDAPLPN-----ASFTL----NITVL
VNG LPSECQGLCTLSLREETT PIVDSLTTNISGSLTMVLIRGQKLDITTDEPMVFVDNHL
PCVVTFFNAS-HVACRISDLTPGLHYVSIFH TRIGYACFGNVSRHFHIL PEVSHYFPKNF
SIHGGSLLSMEGIALRGENSTLVFIGQQACLTVSI-SSKFIQCIVPAGNGSGGLVIEVD G
LSYRMGVIGYSNAFTPQLLSISQTDD-ILTMVVAQVSGAKNVDIFIGMSPCVGVSG----
NYTVLQCVVPPLPAGEYPVRGYDRMRGWASSVLVFTSTVTISAVTENFG-CLGGSLVHVF
GGGFSPGNISAAVCGAPCQVLANATVSAFSCLVPPLDVSLAFLCGLKHAEESCEASSSSY
VQCDLTFAVGTETLPQSWPYLYICEESPQCLFAPDHWTE---SAFPW-FSGLFLSPKVER
DEVLIYNSSCNIAMETEAKMECETPNQPITAKITEIRKSRGQNTQGSFSFHFCRRWSRA H
SWFPERVPQDGDNVTVENGHSLLLDTNTSIL-SLLHVKGGKLIFMDAGPIELRAHSILIS
DGGELWIGSEDKPFQGKAEIKLYGSSHSTPFFPYGVKFLAVRNGTLSLHGLLPEVTITHL
RAAASAQDTVLALEDAVDWCPGDEVVIISGIGFEGAKPTEEIVIVEAVHKTDLHLRSPLR
YSHNFTENWVAGERHILKVTVVLLSRRVTIQGNLTAERKKHLASCQEASASEGNLQDCFY
SKSEKILGSRDLGARVIVQSFAEEPSRVQLKGVQFRALGQAFRKHLSSLTLVGA--MRDS
YIQGCTVWSSF-SRGLSMSRTLGLKVDSNVFYNILGHALLVGTDMDIKYM-----SWEAT
PEKT-----TEQGNLIRNNVIISVSGTEGLSSPETLTPSGIYIRNPTNIIEGNRVYVAGL
GYFFHLVTSQTSQAPLLSFTQNIAHSCTRSGLFIYPQFRPPWDNGRGPTLFQNFTVWGSA
GGAQI-FRSSNLHLKNFQVYSCRDFGIDILESDANTSITDSLLLGHFAHK---GSLCMSA
GIKTPKRWELIISNTTFVNFDLTDCVAIRTCAGCSRGQGGFTVKTNQL--KFINSPNLVA
FPFTHAAILEDLDGSLSGKNRSHILASMETLPASCLVNESFSQIVHGSVCGEDVLFHRMS
IGLANVPDVSYDLTMTDSRNKTTTVNYVHDTLSNLYGWMALLLDQETYSLQFD-TPWIN-
SSLQYSATFGSFIPGNYLLLVHTV-LWPYP---DIHVRCGNQVGRSLPSLPSPGRDQGCD
WFFNTQLRQLTYLVSGEGHIQVTLQVKEGV-PPTISASTSASESAFKWSLPEAWTGIEEG
WGG--HNHTIPGPGDDVLILPNRTVLVDTNLPVLRGLYVMGTLEFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVSCDRFNGILIDPGTIGIYGKVQLHGACP
KKSWTRLAADIASGNERIIVQDTVDWRPHDKIVLSSSSYEPHEAEVLTVKEAQAHHVKIH
EQLKHRHVGSVHVMEDGRSIRLAAEVGLLTRNIQIQPDISCRVRLLVGSFRKSSSEEFSG
VLQLSN---VEIQNFGSPLYSAVELLNASAGTWIISSTLHQSCGGGIRVAASHGIILKDN
LVFGAVGHGIDLQGQNFTLSNNLVVLITQSAWSTMWVAGIKVNQAKDISLDGNVVAGSER
LGFHIRGHRCSSPEALWSDNVAHSSLHGLHLYKENGFDHCTGISGFLAFKNFDYGAMLHV
ENSVEMENITLVDNTIGLLAVVYVSSAPQGHTENVQVTLRNSVIVATSSSFDCIQDRVKP
RSANLTSTDRAPSNPRGGRVGILWPVFTSKPNRWPQEPWHRV-RNGHSISGMMKLQ-DVT
FSSFVKSCYSDDLDVCILPSVENTGIMHPIIAERTKMLKIKDKNKFYFPPLQA-RKGLEM
LVCPESDCENPRKYLFKDLDGRALGLPPPVSVFPKMEAEWTGSFFN--TGTFREEQKCTY
RALIQGYICKQTDQVILILDNVDATWAMRKLYPVVSITRDFVDTFSGVNFNTPCSASGSV
STFYSILPTREITKVCFVEQPPQVLRFFLLGNKSASKLLLAIFYHEFQSPRVFIGESFIP
PILVQSTSSLLDESLGSNYFSILDNLLYVVLQGPEPIEIRSGVSIHLALTVTFSVLEKGW
EIIILERLTDFLQVHQDQIRFIYEMSGNEATLKAIADNKAKRKRNCPTVSCASH-Y-RVG
QRKPLMMEMSS-YSVPP-TTVETVSKVIVIEIGDLPTIKSTGLISYLSSNKLQNLAHQII
TAQQTGVLENVLNMTVGALLV-TQSKGVTG---YGNTSSSKTENLIYIRPYALSVLVQPS
DGEVGKELTVQPRLVFLDKQNRRIESLGPPSEPWTISVSLEGTSDSVLK--GCT-RAESQ
DGYVSFSNLAVLISGSNWHFLFTVTSPP-GVNFTARSRSFTVLPVRRSEKSTIILAASLC
SVASWLALCCLVCCWLKKSKS--RKIKSEDISEFQTNSQKN----H-IHISSKH------
PRS-QE-TKKEDAMMGEEIKMKVIVD-RL-NQLPHQ-SLNGVSRRKVGRRAAQKEG----
-GRREEVVAPAPSITGVTSQGH-TCDPGSPAQQVYLQETGTWKEAQEQLVRYQMAG--QD
QRLL-LCPDLRQEREQMQ-GQTPLSQERGHLGLSQEKKASCGAT----------------
--------------------------

-------MTAWLISLMSIEVLLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGVL
YPNNGSQLEIHLVNMNMVAPALPSIPCDVFPVF--LDLPVVMCQTRSLL--SEAHEGLYS
LEAYFGGQLVSSPSPGPRDSCTFKFSKAQTPIVHKVYPPSGVPGKLIHVYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMIHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRHV--SPKKIECTTRAPGKDARLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNT---DERTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
RGL-EVSNSDGDLTSGTEPFCGRFSLHQPRHLVVTPPAAQKGYRLDQYTHLCLAYKGHMN
KILQMTVSFTIGFQNMV-KNTTCDWSL----TRTSPKSWQFHCTDLWETCVRCSGDLQPP
PTNSPVLVHQIDLVPLA---QETGLFYVDEIIIADTNVTVSQADSGTARPGENLVESVSV
VGSPPVYSVTSWLAGCGTELPLITAHSVPTEGTEE---------GSGLVLATTQRQQRTS
PPLGGHFRIQLPN-TVISDVPVQISAHQLHQLLQNNADDFTSRYLNASDFSVKEDLYTCY
ERVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKTNCKVIFSNQTNVVCQTDLPPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRILCKVPPR
GKDG-HIVNVTVIRGNHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGDTLVIGVAR-
-LVNYTDLDVEVHIQDALALVHTQSAWGLEVALPALPAGLHRISVSINGISIHSQG VDLH
IQYLTEVF SIEPCCGSLLGGTILSISGVGFSRDPALVWVLVGNRSCDIVNLTEASIWCET
LPAPQIPD-A GAPT--VPAAVEVWAGNRSFAHGPSPSLVGNGFIFMYEAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSVPL
HSLEAGIYPLQVRQKQMGFANMSAVPQQFAVT PRIMAIFPSQGSACGGTILTVRGL-LLN
SRMRSVQVDLS--GPFTCVILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGITSECH GNCTLFVREETSPVMDT LSTNTSGSLTTVLIRGQRLGTTADEPMVFVDDQL
LCNVTFFNAS-HVACQTRDLAPGPHYLSVFYTRNGYACSG NVSRHFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIQCIVPTGNGSAALEIEVD G
LWYHIGVIGYSNAFTPELISISQSDG-ILTFAVAQISGAANIDIFIGMSPCMGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCSLKHEEDSCEAARHTY
VQCDLTVAVGTERMLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDTVLALEDAVDWHPGDEVIIISGTGVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHRILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRSSF-SR GLSMCGTLGLKVNSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCARYGLFVYPKFQPPWDKVTGTTLFQSFTVWESA
GGAQVNFRSSNLRLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSRGQGGFTVKTSQL--KFVNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLANAPEVSYDLTMTDSRNKTTTVNYVRDTLSNPHGWMALLLDQETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILRVKEGM-PPTISASTSAPESTLKWSLPETWQGVGEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLEKPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYP
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIILSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGTVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSAGSWIISSTLHRSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHRCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRTGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
RFLMQGFICKQTDQVVLILDSTDATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFIHEIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVG
QRRPLMMEMNS-HRSSPPTTVETISKVIVIEIGDLPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENILNITIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYALSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLR--GCT-QAETQ
DGYVSFYNLAVLVSGSNWHFIFTVTSPP-GVNFTARSQSFAVLPVTRKEESTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKR------
RESQ-G-PKKEDAVVAEDMRMKVVPG-RL-NQCPHE-LMNGVSRRKVSR-----HT----
-VREEEAAVPAPGTTGITSHGH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL-------QERQQLP-GQSWLSKQSGRLGLSQEKKASCGATEVFCLHSVHLEAIQEQ
LSSGKVWAFGLKGRIFQILLDNKQGK

------VMPAWLITLLSMGVLLLADPYLSVQIEPVEGSLAGGTWITVVLNVLE---NSVL
YPNNGSQLEIDMVNL--AVPALPRIPCDVYPVF--VDLPVVTCQTRSLL--SEAHAGRYS
LEIRSGERVLGGPCSGSLDGCTFKFSKAQTPVVYQVNPPSGVPGQVIQVYGWIIADQLET
FDPDADYIDSPLILEA---------GRDKWLTPCSVVNKQTGSCFPIQEEHGLGTVQCRV
EGDY-IGSQNVSFSVFNKGR-SMVHKE-AWLISAKQD----LFLYQTHSEIQSVFPKVGS
LGGRTDITITGDFFDSSAQVTIAGIPCDIRRV--SPRKIECTTRAPGRGARLTAPQAGNR
GLLFEVGDSVEDVELNKATPGYKWQIVPNASSPSGFWSKEGQIFRARLSGFFVAPETNNY
TFWIQADSPASLYFSCSEEPRTKV-EVASVGVGTADWFDSWERNG---NEGNWQQKTTKL
ELRGSAKYYLEAEQLGIAPSRGMRIGVQIHNTWLNPDVVNTYLLEKHQIRARAQRLPEIQ
MLNVSA-TGSFFLAWNNVSSQPVPANATAQQVQTTIEELLAVKCHLEPVSAHILLRLGFE
QGL-EGSSSDGVLTSSTEPFCGRFSLGQLQHLILYPSPDKNGYQGDQYPYLCTAYRSHIN
RTLTMTVSFVFGFQNVT-KNTTCDWSL----TEPHPESWQFTCINLWDTCVRRSEDLPSS
LANTPLLVQRIDILPVA---PKADLLYLDEIILADTSITVSQADPGTARPGGNLVESVSV
VGFPPVYSIAFWLAGCGSELPLITARYVPAEGTGE---------GSELTEVTAQRLQRTS
PPLGGHFFLQLFD-TVIPDVPVHMSSRQLHKLLQDNADASTSGYLNVSDITVTKELNSCY
EHVWTLSWTTQIGDLPNFIR---VSDQNLTGVNPAVIARVVYDGGVFLGPIFGDMLATAN
QQTQVAVQVNDVPAHCSGSCSFQYLQESTPSVDYVRHSPGCDV---NLLVYLTGTGFPRD
AQSLQVTVNQTRCEVIFSNETDVVCELDLLPVGVHRILMLVR HSGLAVNASG-EGLFLYV
E PRLVA-VEPATVAEIGGLWVTIRGCHLEGTSLVLFGTQSCAIDAISSNSQQIRCKVPPR
GKDG-YTVNVTVVTGEHSTVLPRAFTYVSFLNPVVVSLSRNRSSIA--GGEILFLGMAR-
-LTNDTDLDVQIRVQNTSAQVLTQTAWGLEALLPPLPTGIHTISVFINGVSIRAQGVDLH
IQYLTEVFSVEPCSGSLLGGTILSIAGTGLGGDPALVWILVDNQTCDIVTLTDMNVWCET
PPVALSPG-ADVLS--V SASVAIWVGNTSFLHGP--SLVEKGLTFMYEATTTPVVTALWE
ELTNDSLRFYVEGNNLSDSAILFGTLKCDLEVQSF------------VENTSLSGCSFPL
YSLEAGVYPLRVRHKLMGFANMSAVPQKFELS PRIKAIFPTRGSVCGGTILTVKGV-AFN
SRRRSVHVDLS--GPFACVILSLRGHTVLCQTKLVGYHFSA-----VSFAL----NVTVV
VNGLASKCAGNCTLFLQEEATPTVDVLIASLNGSITTVLMRCQQLGTTDAALTVFVDDQL
PCHTTFFNTS-HVACQMSNLTPGLHYLSAVHTHTGYACLDSVSRNFFIAPQVFDYFPKNC
SIHGGNLLTIKGTALRGRNATFVYVGQRVCLTVNI-SYELIQCIIPAGSGSVALDIQVDG
VLCHAGLIGYSSV FTPELLSVSQSHD-ILTFSVAQISGAANVVIFIGKSPCMGVSG----
NRTVLQCMVPLLPAGEYPVTGYDHSRGWASSALILEQRATVTSVTKNF-GCLGGSLLHVF
GAGFSPGKISAAVCGAPCQVLANATVSAFSCLVLPLDVSLASLCDLRPAEDSCEVSSHTY
MRCDLTIAIGTKRLPGSWPYLYCCEESPQCLLAPEHRAE---PASPP-FSGLFLSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPIIAKITEIQKSRGQNTQGNLSFQFCRRWSRPH
S WFPHRLPQDGDSVTVETGQLLLLDANTSLL-NSLHLKGGKLIFMEPGPIELRAHSILIT
DGGELHIGSEFKPFQGKAQLKLYGSSHSTPFFPYGVKFLAVRNGTLSLHGAVPEVTVTSL
RGTACAGDTTLVLEEAVDWRPGDEAVIISGMSVEGTGSMEEVVVVETVHNAQLRLRTPLR
YSYNITENWVAGKNPILKATVALLSRNIVIQGNLTLERVKRLHSCQEANAAEGNLKHCLY
YKSEKTLGARDLGARVIIQSFPEEPSLVKLKGVQFRDLGQAFRKHPSSLTLVGA--LRGS
YLQSCAIWGSF-SRGLSMHKTWGLRVESNIFYKIIGHALLVGTYMDRKFM-----TSETV
IGRKN--DWREQGSTIRNNVIISVSGAEGLSNPEMLAPAGIYTFSPTNSIEGNRVCAAGY
GYVFYLVTRQTSQAPLLSFMLNTAHSCTRYGLLIYPEFQPLWNNDTGFTLFQDFMVWGSA
GGAKI-FRSSNLHLKNFQVYACRDSGIDILESDADTVVMDSFLLGHFTHK---GSLCMSA
GIKTPKRWELTISNTTFVNFD-LNCVAIRTCSGCSQGQGGFTVKTREL--KFENSPNLVA
FPFPHAAVLEDLDGSLSGKNGSHILPSMETLPDTCLVNASFSHIVPGSICGESVVLHRMS
IHLDKALEVPKNLIVTDGKNKTITVKYVGDTLSNSYGWMALLLDQETYSLQFQNNDWME-
RSSQYLATFGSFAPGNHLLLLHGD-LPPYP---DILIRCGSRLGQSLLSPPLPSRDRGCD
WFFNSRLGQLTYLVSGEGQVQVFLQVREGV-PPTVSASTSVPESALKWSLSETWKDVAEG
WGG--YNQTLPGPGDDVLILPNRTVLVDTDLPVLRRLYVMGTLEFPVDRSNVLSVACLLI
AGGELKI--GTLTNPLEKEQRLQIILRASEEIFCDHFDGIRVDPGTIGVYGKLSLHGAYA
KKSWVH LGADIAPGNERIIVDDEVNWQPHDKIVLSSSSYEPHEAEVLTVKEVKGHHISIY
ERLRHRHIGSAHIMEDGQRIPLAAEVGLLTRNIKIQPDSSCRGRLLVGSFRKSSREEFSG
VLQLLN---VEIQNLGSPLYASIEFTGVSAG SWVVSSTVHQSCGMGIYASTSHGMVLNDN
VVFGTNGHGIDLEGLNHSLTNNLVILTMQSTRSFPWVAGIKVNYAKDVILRGNVVAGSER
IGVHICGHSCSS-EMLWSDNVVHSSLHGVHLYKRHEPNNCTGVSGFLAFKNFDYGAMIQT
ENSLVLQNITLVDNTIGLLAVASVSSAPPSSIIDVQIVLRNSVIVATSSSFDCIQDRKTP
QSANWTSTDRAPSNARGGRIGILWPVFTSEPNQWPQEPWHRV-RSGHLISGIMKLQ-DVT
FSSFVKSCYSGDLDICILPNEYSTGIMYPITAERTRMLRMKDKNKFYFPPSQP-RKDLEE
TVCYESDWESPRKYLFIDLDGRTLGLPPPVSVFPKTEAEWTGSFFN--TGIFREEQKCTF
RAMIQGFFCKQTDHVILILHNVDVPWTVLKSYPLVSVTNGFVDTFSRVKDSTLCSSTSSM
STFYSILPTRQITKVCFVEQTPQLLRFFLLGNRRASKLVLAVFYNEIQSPRVFLEKRFIP
PTPVESASSLLDESAGANYFDIMNNLLYVVLQGEAPVEIHSTVSIHLAFTVTFSVPEKGW
ERVMLERLTHFLQIDPNQIKFKLEMPGNKETLEAIANSRGKRKRNCPTVTCGGA-STRSG
QRRPLMAEVMP-YKITPTTSVETLSKVIVIEIGDLPNVRSTEFIPSLPSNRLQNLAHQVI
TAQQTGVLENVLGITVGALLV-TQSEGVAG---YRNASHLRTGNRIYTRPSILSILVQPS
DGEVGVDLPVQPQLIFLDEKNQRVESLGLPSEPWIISASLEGASDSMLK--GCT-QAETQ
DGYVSFSRLAVLISGSNWRFVFTVTSPP-GANFTARSKTFAVLPVAHKERSTIILALSLC
SVVSWLALSCLICCWFRKNKN--RKIKPEDISESQAKGQ-K----N-THNSSKH------
RGVQVK-KTKEDTVMREDMRMKVMQG-RQ-NQFPQQ-SMDGVSKRNVSRRAVPE------
----EGAATPAPRIPRITSQGL-TCVPGSLARQLTLQEPGNWKEAQKQLLRYQLAG--HN
QLLL-LCPDLRQERQQGQ-ESSQRNNGSNCMGLSPEE-GTCVPSEAVCLHTAPPEAIQ--
--------------------------

------MMPAWLVSLLSMEVLLLAKPYSSFQIEPAEGSLAGGTWITVVFDGLD---RSIL
YHNNGSQLEIDLVSV--AIPTL-RIPCDVSPVFLFADLPVVTCQTRSLS--SEAHAGPYS
VEISFGEQVLATPCPGSLDSCTFKFSKDQTPVLYQVFPASGVPGAVVHVYGRVITNWLET
FDPDVDYIESPLILEA---------GGDKWLTPCSLINRQTGSCFPIQEEHGLGTVQCRV
EGDY-IGSQNVSFSVFNKGR-SMVHKE-AWLISAKQE----LFLYQTYPEILSVFPKVGS
LGGRTDIIITGDFFDPSARVTIAGIPCDIRHV--SPRKIECTTRAPGNEARLTAPQAGNR
GLRFEVGDATKDEELTEATPGYRWQIVPNASSPSGFWSKEGRPFRARLSGFFVAPEINNY
TFWIQADSQASLCFSSSEEPRTKV-EVASVGVGTADWLDSWEQIR---HEGSWHQKTAKL
ELQGGAKYYLEAEQHGIAPSRGMRIGVQIHNTWLNPDVVNTYLLEKHQIRARAQRLPDIQ
VLNVSG-KGNFFLTWGNVSSQPVPANATAQQIQTTIEELLMVKCNLEPLSARVLLRLGFE
QGL-EGSRSDGVLTSSTEPFCGRFSLGQLGHLTLIPEALDKGYQLDRYPYLCLAYRGHMN
KTLGVTVSFLSGFQNIT-KNITCDWNL----TDLHPESWQFTCINLWDTCVRHSEDLQSS
LANTPLLVHRIDIRPMV---PEAGLLYVDEIILADTNVTVSQADSGIPCPGGNVVESVSV
VGVPPVYTIASWLAGCGSELPLITACYVSTEETGD---------GSELVEVTAQRLQRTS
PPLGGHFFLYLSD-TVIPDVPVHMSARQLHKLLQDSADESTSGYVNAGDFTVTEDLNSCY
EHVWTLSWTTQIGDLPNFIR---VSDQNLTGVSPAVTARVVHDGGVFLGPIFGDMLATAN
QQTQVAVQVNDIPAYCSGSCSFQYQQESTPSVDHVCYSLGNDV---SLLVHFTGTGFPRD
PQFLQVTVNKTSCEVIFSNETNVACELALLPVGEHRIFMLV IPSGLAVNASG-EDLFLHV
E PRLDA-VEPSTAAEIGGQWVTLRGSSLEGVSLVLFGTQSCIIDVIRSNSQQIQCKVPPK
GKDG-YTVNVTVISGDHSTVLDRAFTYVSSLNPVIVSLSRNRSNIA--GGEILFLGMSL-
-LVNYTDLDVQIYVQDASSQVLSQTVWGLEVVLPPLVPGIHAISAFINGVSIHSQGVDLH
IQYLTEVFSVEPCSGSLLGGTLLGLSGTGLGRDPALIRVLVDSHPCDIVNVTEVNIWCET
PPAVLPPR-ADVL T--VPASVEIWAGNTSFFHGP--SLVGKGFTFTYEAATTPVVTAMWG
EFRNNSVRFYVKGNNISDSVILLGSLKCDLEVQVF------------GDHMNLSGCSFPL
HSLEARVYTLQVRHKRMGFANMSVVPQKFELS PQIIAIFPTHGSKCGGTILTVKGM-AFS
SRRRSVHVDIS--GPFACMILSLEDHTVLCQTSFVGDQFSE-----SSLAL----NITVL
VNGLTSKCEGNCTFFIEEAATPIVDALTISISGSLTMVLMRGRRLGTTADEPIAFVDDQL
PCHTTFFNTS-HVACQIRDLAPGFHYLSAVHTSAGYACLNSVSRNFFIVPQVLDYFPKDF
SIHGGSLLTIKATVLRGWKATVVYVGRQVCLTANI-SSEFIQCIVPAGNGSAALEVDVD G
VLYHIGFVDYSSIFTPELLSVSQSKD-ILTFTVARISGAANVDIFIGTSPCLGVAG----
NRTVLQCMVPLLPAGEYLVTGYDHSRGWASSTLILVLRATVTSVTGNY-GCLGGRLLHVL
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDVSLAFLCNLRHAEDSCQVRSPTY
LQCDLTISMGTERLPGSWPYIYLCEESSLILFEPNHWAE---SVSPS-FSGLFLSPKVER
DEVLIYNSSCNITMETEAEMECETPKQPITTKITEIQKSWGQNTQGNFSFQFCRRWSRPH
S WFSQRVPHDGDSVTVETGHLLLLDANTSFL-NALHIKGGKLIFMEPGPIELRAHSILIT
DGGELRIGSEDKPFQGKAQIKIYGSVHSTPFFPYGVKFLAVRNGTLSLHGSVPEVTVTY L
QAAAHAGDTVLALGEAVDWHPGDEVVITSGMTVEGAEATEEVVVVETVRNADLHLRNPLR
YSYNFRENWVAGENHILKATVALLSRNIIIQGNLTLERAKLLNSCQEANTAEGNLKHCLY
SKSEKMLGARDLGARVIIQSFPEEPSLVKLKGLQFRNLGQAFHKHLSSLTLVGA--MRGS
YLQSCSVWDSF-SR GLSMHRTWGLKVDSNIFYKIVGHAMLLGSYLDRRFS-----TSENV
TGRKN--GWWEQGSTIRNNVIISVSGAEGLSSSEMLAPAGIYTFSPTNVIEGNRVCAAGY
GYVFHLVTSQTLQAPLLSFNRNTAHSCTRYGLLVYPKFQPPWNNETGFTLFQNFMVWGST
GGAQI-FRSTNLHLKNF QVYACRDFGIDILESDVNTLITDSFLLGHFTHK---GSLCMSA
GIKTPQRWELTISNTTFVNFD-LNCVAIRTCSGCSQGQGGFTVKTRQL--KFVNSSNLVA
FPFPHAAVLEDLDGSLSGKNGSHVLASMETLSDTCLTNASFSQIVSGSVCGEAVLFHRMS
IALANSLNVPKNLTMTDSSNKTITVNYVEDTLSNYYGWIALLLDQETYLLQFE-GPWMN-
RSLQYSATFDSFAPGNHLLIMHRD-LPPYS---DILLRCGSQVGQSLPSHPLPSQDRACD
WFFNRQLRQLTYLVSGEGQVKVFLQLKHGA-PPSVSASTSVPESASRWSFPETWQDVEKG
WGG--YNHTIPGPGDDVLILPNKTVLVDTDLPVLRCLYVMGTLDFPVDRSNVLSVACLLI
AGGELKV--GTLENPLEKDQRLLIFLRASEGIFCDHFEGIHVDPGTIGVYGKLRLYSAYP
KKSWVH LGADIAPGNEKIIVHNAVDWQPHDTIVLSSSSYEAHEAEVLTVKEVKGHHIRIY
ERLKHRHIGSAHIMEDGQQVHLAAEVGLLTRNIRIQPDSPCSGRLLVGSFRKSSGEDFSG
VLQLLN---VEIQNMGMPLYSSIEFTGVSAG SWVISSTVHQSCSVGIHASSSHGVILNDN
VVFCTNGHGIDVEGQNYSLTNNLVILTMQSANSSPWVAGIKVNYAEDIILHGNVVAGSER
LGFHVSGHGCSS-EVLWSDNVVHSSLHGLHLYKKHESNNCTGVSGFMAFKNFDYGAMVQT
ENSVDIQNITLVDNTVGLLAITYVSSALLSSVSTVQITLRNSVIVATSSSFDCIHDRKAP
QSANWTSADRAPSNPRGGRIGILWPVSASEPSGWPQEPWHKV-RSSHSVPGIMKLQ-DVT
FSGFVKSCYSNDLDVCILPNEYSTGVMFPITTERTRMLRIKDKNKFYFPLLQS-SRDLVG
TICPTLDCEYPRKYLFTDLDGRTLGLPPPVSVFPRTEEEWTGSFLN--TGISREEQKCTF
RAVIQGFFCKETEHAVLILDNVDATWTIPKSHPLVSVTNGFVDTFSIVKDSDLCSPTSSL
STFYSILPTKQMTKVCFPDQTPRFLRFLLLGNRRASKLILAVFYNEIQSPHVFLDKSFIP
PTPLESAFSLLAEPAGANYFDIMNNLLYVVLQGEEPVEIYSSISIHLALTVTFSVLEKGW
ERAMLESLTDFFQIDPNQIRLTLEMPGNKETLEVIANSEGKRNRNCPTVTCGGP-SIRYG
QRRPLMAEMTS-LKTTPATTLETFSKVIVIEIGDLPNIRNSEPIQSLPSNRLQRLVNQVI
TAQQTGALENVLGMTVGALLV-TQSKGVTG---YRNASSLITRNLIFTRPSELSILVQPS
DGEVGIELPIQPRLVFLDEKNERVETLGLPAEPWIISVSLEGASESMLK--GCT-QAETR
DGYVTFSRLAVLISGSNWHLVFTVISPP-GTNFTARSKAFAVLPVASKERSTIILALSLC
SVTSWVALSCLVCCWLKKNKT--RKIKPEDISESQAKEQKK----N-TRISSKP------
RGLQVK-TAKEDTLMGEDMRMKVMQG-MQ-SQFPRH-SMDGVSKRKVSRLAVPE------
----ERTATPAPKIPRI------TCVPGPLAQQLTLQEPGNWQEAQQQLLRYQLAG--HN
QLLL-SRPDLRQERKQGQ-EPSQLDKGSDCTGLAQEK-DTCVPTEAFYLHPAPPETIQ--
--------------------------

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-----------------MVLFLARVRFLPSEGRSE---------DQFSVNLSSQRLQRPS
PPLGGVFQIQLPH-TLISGVPVHISSADLRELLQNSADDFSAQYLKASDFTVIKDLSSCY
RHVWTLTWMVKTGDLPNLIK---VSAESLTGLSPAVTARLVYDGGVFLGPILGDMLATAH
PLPQVKIRIRTQVSWLPGSCSSDA---TLPAVCALLVLSEDGF---HLTAFITGSGFPAV
RQDVQVSVSERNCAVTSANQSHVTCRMEALPVGEHRVQVRV KPTGLAIHARGGDAIYLSV
K PRLSA-VEPSSSSEIGGRWVTLGGTSLEGVSLILVGSQPCPIRNTTISSLSIQCRLPPR
GDDG-PTVNVTIISGNQSAVLPDAVTYSLSLNPIVLSLSRNGSNTA--GDQTLFIRTSS-
-LEEYTDLDVQVHVGGDPAWVREQVPEGFYVTLPPLPLGWHPISVTMNGIRIGSDGIDLQ
IQYLLEVFSIDPCCGSLLGGTTLTLSGLGFSEDPALISVSVSSQACDILQSTEDTIWCQV
PPAFPMAS-LDS--Q TVPAPVEVRIGKQSIAHGAPSLAGQSNLTFWYQANLTPLVTALQG
ETVDGRLRLRVEGTHLSSSEAMLGDVTCDLELRVT------------NGTESLAECSLPL
GSLEAGTYPFRVLQKQMGFANMSAGLQNFTVA PQITGVLPGQGSICGGTLLTVKGS-AFR
SRSKEVEVDLP--GPYTCELRSLGDREISCLVLPGDGSSSV-----ASQVL----NVTVT
VNGIASACLESCSLQLVEDATPTVDALTLRDDGRLTKLLIRGQRLARGSNELTVVVDDQL
PCPVTFFNETGLVECQVIDISPGHHHLSVFNERNGRACMASGTSGFSITPRVLRFFPPSF
GVWGGGLLTLQGAALQGQNTTMVLVGEEPCLPLDV-GSGLIRCVLPAGNGSVPLKLEID G
VAYPTGAIDYEEASTPVLLFASPPEDLILSIGVAQISAVENMRILIGESPCLGVNG----
NWTVLRCLVPSLPAGEYQVRGHDLLRGWASSTLTYVSEVTVASISSNFGKTK-HWRIRAR
YPGIPPGNISAAVCGVPCTVSDNATTTDFSCQVRPLNASLAFLCSLRSLEMICEASSHPA
VQCEVTIGPGTGKPLAAGSYIYLCKDGPACPITLGGRTH---PDTPFNLP-SRFSPKVER
DEVLIYNSSCNITMETEAEMKCEGPNQPITAKITEIQKQPGQNTQGNFPLQFCHGWSWD H
SWLPEGRPRDGDNVTVESGHSLLLDTNTSIL-ASLHVKGGKLIFVGPGPIKLRAHHILVT
DGGELRIGSPEEPFPGTAQIQLYGSSHSNTFFPYGAKFLAVRNGTLSLHGESTGMISLRP
GRLECRLKTPVILRDAVDWQPGDKAV-VSGLGLEGSSQQDEIITIATVLDADLHLQSPLR
YSHGFVEQRVAGRRLVLRATVALLSRNIVIRGNLTGERMAHLGLCAEAGLTIDASQPCLY
ERSERKLGSRDMGAVVIVQSFQGEPSRVHLQGVQFQHMGQAFQKHQSALTLAGP--MGDS
YIRDCSVWDSF-NRGLSLLRTSGLRVDRNVFHNILGHGLLVGKSGEPAGS-----LSTFL
SGFKG--DWSDQGNRIRSNAVIGVSGTEGLSNVEKFSPAGVYILSPVNVLEGNTVCSAGY
GYFFHLLTNETSRAPLLSFSQNVAHSCTRFGLLVYPRYHPFQVNGSSPYLFQNFTTWGNQ
GGIQI-FRSSNLQLQNFQVYSCKDFGIDTLESDENASVTDSLLLGHFTQK---ESFCMAS
GLQAPKRWDLVVSNTTFVNFDRNNCIAI-TCAGCYRGQGGFTVKVKQL--RFANSPNRVA
FPFPHAAMLEDLDGSLSGQVGNLVLPTVETLGSSCLVNISFSQAAQGSVCLGGVVFHRMS
IGLDKAPDVMCDLTVTDSSHRNTTVNYVPDTLSNLYGWMALLKGQETYTLRFA-TPCVN-
RSLQYSATFDHFTSGDYLLVVHSD-LPPFV---DVLVTCGKRRGRPLQSLPTLSHDKGCD
WFLNSPERRLTFLVAGEGQVHIKVQVKESL-PPTTLAPSAAPEATLKWSLPQSWQGVKEG
WGG--YNDTLPSPGDDILILPNRTILVDVDLPCFKGFYVLGTLQFPVDRSNVLCAACIVI
LGGELKV--GTFLSPLETGQGISILLRASEGVSCDRLAGVSTNPGTIGVYGKVELHSGYP
RKSWTHLGTDIAPGNERIVVEDAVDWKPQGRIILSSSSYEAHEAELLTVKEVNDQHLQIH
ERLTYRHVGSSHILEDGRSISLAAEVGLLTRNIQIRSDTPCTGTLTVGSVQLPSGEEFSG
VLQLSN---VEIQKFGSPQHPTIDFSIVSPGSWIHSSVIHQSCGGGIRATKSRGISLHDN
IVFNTAGHGIDLEGDDHSLTRNLVVLTKQPAGCPDWVAGIKVNRANGTSLLRNAVAGSER
IGFHIQGHKCSPTESLGADNVAHSNLHGFHLYKGDGFHDCTKISGFLSYKNFDYGVMFHL
ESAVEVENVTLIDNGVALLPVAYGSPARAPALRKQRIIVRSSVIVATSSSFDCIRDRIRP
LSANATVRDRAPLNPQGGRVGVLWPGFTSGQNQRPRDPWHKV-RNDPAIVGIMKLE-EVT
FCNFVKSCYSDDLDVCILPNPGSTGIMHPITAVKTQMLHVKDQSKFYFYSSPP-REDLGS
EDCLKWGCESPRKFLFEDLDGSALRLPPPVSVFPKSESEWTDSCFN--TGTFREDRKCSF
RPGMGSYVCKQTDYAILVLDKLEISEENKEPPSVVSVTESFVEAFSSVDVQNSCSEPGPT
PAFYSILPTSHPTTVCFGGKTPPVMRLYLTGSERAARVVLSVFYDEPQSPRVFYQESFIP
PSPVGSASFLTLGTVGSNYFSFQDNLLYIILEGDDPVEVCSGSSVYVAFTVAEVISQEIH
VLVVQQQLADFLQVSCDHLRVVYSMPGDEDNLRGIADNVAKRKRHCPPVASCPEYQKRTS
KRRSLEE-KAVDWMWPSHFETATSSTVMIIEIGDPPAQGRTESSPSLSRPMLQGFTHQII
TAQQTGMLQKALDMPVEALLV-TQPTGTIG---SGRNASLNTGNLVYVQPHTLSVQTQPS
NGEVGKELPVQPHLVILDKKGRRVEILGPPWEPWIVQASLEGAPEMMLQ--GCP-RLEVQ
DGWVRFTNLAVLNSGSNWHLVFNVVFPP-GANLTARSRPFVVLPVEEGHTSTIIMATILC
SAASWIALCFLVFCWSKKSQT--KKPKNGQIAELQSGGNME----H-PHLQPRHPTRL--
QRPQER-TRQDHGMIREDIEMKTTVG-KL-DQFCQP-TVNGGSRRTSNRVVHERADKRKA
GSPGMEDLAPGPGYGP--------VPPLHPLAPQGGGEVGDWRDARERSFGYDLEDVAQK
DLLLLLHPNFSQDRMPLR-GQRSAGKSDSEVSHHRD---------EICCHVNTKAVHHSS
LPAGPIWEQL----------------

------MMLAWLVSLLSMEVLLLAKPYSSFQIEPAEGSLAGGTWITVVFDGLN---RSIL
YPNNGSQLQIDLVSV--AIPTL-RIPCDVSPVF--VDLPVVTCQTRSLP--SEAHAGPYS
LEIGSGEQVLGAPCPGSLDSCTFKFSKDQTPVLYQVYPASGVPGEVVSVYGRVITTWLET
FDPDVDYIESPLILEA---------GEDKWLTPCSLINRQTGSCFPIREEHGLGNVQCRV
EGDY-IGSHNVSFSVFNKGR-SMVHKE-AWLISAKQE----LFLYQTYPEILSVFPKVGS
LGGRTDIIITGDFFDPSARVSIAGIPCDIRYV--SPRKIECTTRAPGNEARLTAPQAGNR
GLLFEVGDATKDVALTEATPGYRWQIVPNASSPSGFWSKEERPFRARLSGFFVAPQTNNY
TFWIQADSQASLCFSSSEEPRSKV-EVASVGVGTADWFDSWEQIG---NEGSWHRKTTKL
ELQGGAKYYLEAEQHGIAPSRGMRIGVQIHNTWLNPDVVNTYLLEKHQIRAQAQRLPEIQ
VLNVSG-KGNFILTWGNVSSEPVPANATAQQIQTTIEELLVVKCNLAPFSARVLLRLGFE
QGL-EGSRSDGVLTSSTEPFCGRFSLGQLGHLILIPEAADKGYQLDRYPYLCLAYRGHMN
KTLDVTVSFLFGFENIM-KNITCDWSL----TDPHPESWQFTCINLWDTCLCHSEDRQSS
LANTPLLVHRMDIRPVV---PDAGLLYVDEIILADTNVTVSRADSGRAYPGGNVVESVSV
VGVPPVYSIASWLAGCGSELPLITACSVSTEGTGD---------GYELIEVTAQRLQRTS
PPLGGHFFLYLSD-TVIPDVPVRMSARQLHKLLQDSADESTSGFLNAGDFTVTEDLNSCY
EHVWTLSWTTQIGDLPNFIR---VSDQNLTGVKPTITARVVYDGGVFLGPIFGDMLATAN
QQTQVAVQVNDIPAYCSGSCSFQYQQESTPSVDHVWYSLGSNV---NLLVHFTGIGFPRD
AQFLQVTVNKTSCEVLFSNETNVACELSLLPVGVHQIFMLV IPSGLAVNASG-EDLLLHV
E PRLDA-VEPSTAAEIGGRWVTLRGSSLEGVSLVLFGTQSCAIDVIRSNSQQVQCEAPPR
GKDG-YTVNVTVISGDHSTVLARAFTYVSSLNPVIVSLSRNRSNIA--GGEILFLGMSL-
-LVNYTDLDVQIYVQDTSAQVLSQTVWGLEVVLPPLVPGIHAISAFINGVSIRSQGVDLY
IQYLTEVFSVEPCSGSLLGGTLLSLLGTGLGRDPALIRVLVDNHPCDIVNLTEVNIWCET
PPAVLPPT-ADVLT--VSAS VEIWAGNTSFFHGP--SLVGKGFTFTYEAAATPVVTAMWG
EFRNNSVRFYVEGNNISDSVILLGSLKCELEVQFF------------GDSMNLSGCSLPL
HRLEAGVYTLQVRHKRMGFANMSMVPQKFELS PQIIAISPTQGSKCGGTVLTVKGM-AFS
SRRRSVHVDIL--GPFACMILSLEDHTVLCQTRFVGDQFSE-----ISLAL----NITVV
VNGLTSKCKGNCTLFIEEAATPIVDALTISISGSLTMVLMRGRRLGTTADEPIAFVDDQL
PCHTTFFNTS-HVACQIRDLAPGFHYLSAVHTSAGYACLNSVSRNFFIVPQVLDYFPKDF
SIHGGSLLTIKGTALQGWKATVVYVGRQACLTVNI-SSDFIQCIAPAGNGSAALEIDVD G
VLYDIGFVDYSSIFTPELLSVSRSQD-ILTFTVARISGAANVDIFIGTSPCLGVAG----
NRTVLQCMVPLLPAGEYLVTGYDHSRGWASSTLILVLRATVTSVTKNY-GCLGGRLLHVL
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDVSLAFLCDLRRAEDSCKVRSSTY
LRCDLTVSMGTERLPRSWPYVYLCEESSLCLFEPDHWTE---SVFPS-FSGLFLSPKVER
DEVLIYNSSCNIAMETEAEMECETPNQPITAKITEIQKSWGQNTQGNFSFQFCRRWSRPH
S WFPQRLPQDGDSVTVETGHLLLLDANTSFL-NSLHIKGGKLIFMDLGPIELRAHSILIT
DGGELHIGSEEKPFQGKAQIKIYGSVHSTPFFPYGVKFLAVRNGTLSLHGSVPEVTVTY L
QADAHAGDKVLTLGEAVDWKPGDKAVITSGMTVEGAEATE-VVVVETVHNADLHLRNPLR
YSYNFRENWVAGENHILKPTVALLSRNIIIQGNLTFERAKLLNSCQEASTTKGNLKHCLY
SKSEKMLGARDLGARVIIQSFPEEPSSVKLKGVQFRDLGQAFHKHLSSLTLVGA--MRGS
YLQSCSVWNSF-NR GLSMHRTWGLKVDSNIFYKIVGHALVLGSYLDRRFN-----TSETV
TGRKN--GWWEQGSTIRNNVIISVSAAEGLSGSEMLAPAGIYTFSPTNVIEGNRVCAAGY
GYVFHLVTSQTLQAPLLSFNWNTAHSCTRYGLLVYPKFQPPWNNDTGFTLFQNFMVWGSA
GGAQI-FRSNNLHLKNFQ IYACRDFGIDILESDGNTLITDSFLLGHFTHK---GSLCMSA
GIKTPQRWELTISNTTFVNFD-RNCVAIRTCSGCSQGQGGFTVKTRQL--KFVNSSNLVA
FPFPHAAVLEDLDGSLSGKNGSHVLASMETLSDTCLTNASFSQIVPGSVCGEAVLFHRMS
IALANSLDVPKDLTITDISNKTITVNYVEDTLSNYYGWMALLLDQETYSLQFE-SPWMN-
RSLQYSATFDSFAPGNHLLIMHRD-LPPYP---DILLRCGSQEGQALPFQPLPSQDRACD
WFFNRQLRQLTYLVSGEGQVKVFLQLKPGV-PPSVSASTSVPESASRWSLPETWQDVEKG
WGG--YNHTIPGPGDDVLILPNKTVLVDTDLPVLRCLYVMGTLEFPVDRSNVLSVACLLI
AGGELKV--GTLENPLEKDQRLLIFLRASEEVFCDYFEGIHVDPGTIGVYGKLRLHSAYS
KKSWVQ LGADIAPGNERIIVRSAVDWQPHDTIVLSSSSYEAHEAEVLTVKEVKGHHIRIY
ERLKHRHIGSTHIMEDGQQIHLAAEVGLLTRNIRIQPDSSCRGRLLVGSSRKSSGEDFSG
VLQLLN---VEIQNMGLPLYSSIEFTGVSAG SWVISSTVHQSCSVGIHASSSHGVILTDN
VVFGTNGHGIDVEGQNYSLTNNLVILTMQSANSSPWVAGIKVNYAEDIILHGNVVAGSER
LGFHVGGHGCSS-EVLWSDNVVHSSLHGLHLYKKHESNNCTGISGFMAFKNFDYGAMVQT
ENSVDIQNITLVDNTVGLLALTYVSSTLLSSVSTVQITLRNSVIVATSSSFDCIHDRKAP
QSANWTSTDRAPSNPRGGRIGILWPVSASEPNAWPQEPWHKV-RSRHSVPGIMKLQ-DVT
FSSFVKSCYSNDLDVCILPNEYSTGVMYPITTERTRMLGIKDKNKFYFPLLQS-SKDLVG
TICPTLVCEYPRKYLFTDLDGRTLGLPPPVSVFPRTEEEWTGSFLN--TGIFREEQKCTF
RAMNQGFFCKQTEHAVLILDNVDATWTIPKSHPLVSVTNGFVDTFSIVKDSDLCSPTSSL
STFYSILPTRQMTKVCFPEQTPPFLRFLLLGNQRASKLILAVFYNEIQSPHVFLDKSFIP
PTPLKSASSLLAEPSGANYFDIMNNLLYVVLQGEEPVEIHSSVSIHLALTVTFSVLEKGW
ERAMLESLTYFFQIDPNQIRLTLEMPGNKETLEAIANSEGKRKRNCPSVTCGGP-SIRYG
QRRPLMAEMTS-LKITPATTLETFSKVIVIEIGDLPNIRTSEPILSLPSNRLQRLVNQVI
TAQQTGALENVLGMTVGALLV-TQSKGVTG---YRNASSLITGNLIYTRPSKLSILVQPS
DGEVGIELPVQPRLVFLDEKNERVESLGLPSEPWIISVSLEGASESVLK--GCT-QAETR
DGYVTFSRLTVLISGSNWHLVFTVISPP-GTNFTARSRTFVVLPVASKERSTIILALSLC
SVASWVALSCLVCCWFKKSKT--RKIKPEDISESQAKEEKK----N-THNSSKP------
RGLQVK-TAKENTLMGEDMRMKVMQG-MQ-SQFPQH-SMDGVSKRKVSRLAATE------
----ERTATPAPKIPRI------TCVPGSLAQQLTLQEPGNWQEAQQQLLRYQLAG--RN
QLLL-LRPDLRQERKQGQ-EPSQLDKGSDCTGLSQEK-ASCITTETFCLHTAPPETIQ--
--------------------------

------IMAGWLLSVMSIEVLLLAEPCLNLRIEPEEGSLAGGTWITVIFDGLE---PGVL
YPTNGSQLEIHLVNM--AVPALRSIPCDVSPVF--LNFPVVTCRTRSLP--SKAHEGLYS
LEVRSGGQVVGSPSSRPQDSCTFKFSKAQTPIVYQVNPPSGVPGKLIQVYGWIITGKLET
FDFDAEYIDSPLILEA---------QGDRWVTPCSLINRQTGNHYPSQEDRGLGTLQCRV
EGDY-IGSQNVSFSVFNKGK-SMVHKS-AWLISAKQE----LFLYQTHSEILSVFPETGS
HGGRTDITITGDFFDNSAQVTIAGIPCDIRHV--SPRKIECTTQAPGKGARLTAPQAGNR
GLLFEVGDASDGLELTEATPGYRWQIVPNASSPFGFWSMEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSQTEEPKTKV-EVASIRVGTADWFDSWEQNE---NEEPWQQKTAKL
ELLGGAKFYLEAEHYGTAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVQAQKLPEIQ
MLNVSG-RGNLFLMWGNVSSQPIPANATAHQIQTTIEELLAVKCTLEPLSANTLLRLGFE
QGL-EGSSSDGDITSGTEPFCGRFSLHQPRQLVLTPTVTEMSYRLDKYPHLCIAYKGYMN
KILKMTVSFTIGFQTIKKKNSTCDWSL----PETSPESWEFTCTDLWDTCMHRFGDLQLP
LSNVPVSIHQIVLLPLP---QETGQLYVDEIIITDTNITVSPVDSGTARPGGNLVESISV
VGSPPVYSVAFWLAGCGLELPLITACSVPTEET-E---------GSGPVHVTAQRLQRTS
PPVGGHFRIQLPN-TEIPDVPVHISARHLQKLLQDNADNFTSRYLNVSDFIVKEDLNSCY
EHVWTLSWSTQIGDLPNFIR---VSDQSLTGMNPAVTTRVVFDGGVFLGPVFGDMLATAN
QHTQVVVRVNDIPAHCPGSCSFQYLQESTPSVHSVWYSLDGDI---NPLVYITGTGFSDD
SQSLQVTVNKMSCKVIFSNQTNVVCQSDLLPVGVHPISVLVR PSGLAVNASG-EGLFLYV
R PRLDA-VEPSRAAEIGGLWATIRGSSLEGVSLVLFGSKSCDIIITTSNSQRIQCKVPPR
GKDE-YSVNVTVIRGNHSAVLPRAFT YVSSLN PMIVSLSRNQSNIA--GGETLFIGMTR-
-LLNYTDLDVEIHIQDTLAQVHAQTAQGLEVVLPPLPAGLHRISVSINGVIIRSQGV DLH
IQYLTEVF SMEPCCGSLFGGTILSISGRGFGRDPALVWVLVGNQPCDMVNLTEVSIWCET
PRAPLLPD-AEALT--I SAPVEVWAGNATFIHGPSASLVGKGLTFRYKVAATPVVTALWG
EVTNSSLKLYVEGSDLSNSVILLGSLKCEVETQSL------------WGNLSLSGCSFPL
HTLEAGVYPVQARQKDMGFANMSAVPQQFVVT PRIMTILPMHGSVCGGTVLTIRGL-ALN
SRRRSVQIDLS--GPFTCMILHLEDRIVLCQINQMGDPLPG-----ASFTL----NVTVV
VN GLPSECEGNCTLFMQEDESPVVDALTIG ISGSLTTLLIRGQRLDSRTDEPRVFIDDQL
PCNITFFNAS-QVLSQISGLTPGLHYLSAVQT SNGYACLGNISRNFSIM PQVFNYFPKNF
STHGGSLLAIVGTTLRGQNTTLIFVGQQACLTVNI-SSEFIQCIVPAGNDSVALEIEVD G
IGYHIGVVGYSDVFTPELLSVSQSDG-ILTFAVARISGAANVDIFIGRTPCVGVSG----
NYTVLQCTTPFLPAGKYYVRGYDRIRGWASSALVFLLKATITAVTENFG-CLGGRLVHVF
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLSLDESLAFLCGLKPKEDSCEVISHTY
VQCDLTVSMGTERLPELWPYLYVCEESSQCLFEPDHWKK---SDFPS-FSGFFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITAKITEIRKSWGQNTQGNSSFQFCRRWSKAY
S WFPEKVPQDGDNVTVENGQLFLLDTNTSTL-NLLHLKGGKLIFMDPGPIELRAHSILIS
DGGELRIGSKGKPFQGKAEIKLYGSSHSMPFFPFGVKFLAVRNGTLSLHGSLPEVVVTH L
RAAAHAQDRVLSLEDTVDWHTGDEVVIVSGTGVEGARPAEETVIVEAVHHADLHLRLPLR
YSHNFTEIWVAGEHRILKVTVALLSRRITIQGNLTSERKTFLASCQEANMAEGNLQHCLY
SKSEKILGSRDLGARVIVWSSPEEPSQVQLEGVEFRDLGQAFQKYMSSLTLVGT--MRDS
YVQGCTIRSSF-SR GLSIHRTLGLKVDSNVFYKISGHALLVGTYMGMSYI-----SWKAI
PGRKN--DWSEQGNMIRNNVIISVSGAEGLSSPEMLTPSGIYIRSPTNVIEGNRVCAAGY
GYFFHLVTSQTSQAPLLSFTRNIAHSCTRYGLFIYPKFQPPWDNDSGPIVLQNFMVWGSA
GGAQI-FRSSNLHLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFNQK---GSLCMSA
GIKTPKRWELLVSNTTFVNFDLINCVAIRTCSGCSQGQGGFTVKTNQL--KFTDSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVSASFSQIVRGSVCGEDVLFHRMS
IGLVNSPDVSYDLTLKDSRNKTTTVNYVHDTLSNHYGWMALLLDQETYSLQFE-NPWIN-
RSLQYEATFDNFAPGNYLLLVHTD-LPPLP---DILIRCGSQMGQSLRSLPSPGRDQGCD
WFFNRKSRQLTYLVAGEGQVQVILLVKESV-PPTISASTSAPESILKWSVPETWKDVEEG
WGG--HNHTIPGPGDDILILPNRTVLVDIDLPFLRGLYVMGTLEFPVDRSNILSVACLVV
VGGELKV--GTLENPLQRAQKLLIHLRASEGIFCDRYSGIRIDPGTIGVYGKVQLHSAYP
KKSWTH LGANIASGNERIIVEDAVDWQPYDKLVLSSTSYEPHEAEVLTVKEVKGHHVRIH
ERLKYQHTGSVHVMEDGQHIHLAAEVGLLTRNIRIQSDTLCKGRLLVGSFRKSSREEFSG
FLQLLN---VEIQNFGSPSHSSIEFTNVS AGSWIISSTVHQSCGGGIHASASHGIILNDN
IVFGTAGHGIDLEGQAYSLTNNLAVLMTQSVWSAIWVAGIKVNRATDIYLHGNVVAGSER
LGFHLQGHRCSS-QVLWSGNVAHSNLHGLHVFKESGPDNCTCITGFLAFKNFDYGAMIQV
ENSVEMENITLVDNAIGLLAAVYVSSVPQRSIRNVQIVLRNSVIIATSSSFDCIQDRMKP
YSANVTSTDRAPPNPRGGRVGILWPGFTSEPNQWPLEPWHKV-RNGYSVSGIMKLE-GVT
FSGFVKSCSSDDLDICILPNVESPGIMHPIIAERTRMLRMKDENKFYFPPLHH-RRDLER
VTCPESDCESPRKYLFKDMDGRALGLPPPISVFPKTEAEWTGSFYN--TGTYREEQKCTY
RALIQGFMCKQTDQVLLIIENVDITWGIQNVYPVVSVTSGFVDVFSSVNANTLCSTPRPV
STFYTILPTRQITKVCFVDQTPQVLRFHLLGNKSTSKFLLAVFYHELQRPHVFLGEYFIP
PTLVQSVSSLLDEPIGANYFNIMDNLLYVVLQGEEPIEIHTGLSIYLAFTVTISVLEKGW
ETVMLEKLTNFLQIDQNQIRFTHEMPGNEGTLKTIVDSRAKRKRNCPTVTCASH-YRRVG
QRRTL-MEMSS-DTILPPATMETISKVIIIEIGDLPRVRSSELIPSLSSSKLQKLARQVI
TAQQTGVLQNVLNMTFGALVV-T--QGVIG---YGNTSSFKTESWIYTRPYVLSVLVQPS
GGEVGKELPVQPQLAFLDEQNRRVESLGLPSEPWIISVSLEGTSDSVLK--GCT-QAETQ
DGYVSFSNLAVLISGSNWHFIFNVTSPP-GANFTARSRPFDVLPVTGKERSTILMATSLC
SVVSWLALICLVCCWLKKSK--NRKTKPEEVPKSQTDDQKN----H-IHVSSKR------
PRSQEG-KEIEDALAEEDMRMKVMLG-RL-NQLPNH-ALDGVSRRKVSS-----HT----
-VPEEGPATAAPSI-----PRG-TCAPGSPSQQLYLQESGNWKAAQEQLLRYQLAG--QD
RLLL-LCPDLRQESHRWQ-GQSQLIKRSSSLGLSQEKKASCGATEKFCLHSAQPETVQE-
--------------------------

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-----------------------QFSAEQTPVVYQINPSSGTPGNLIQIHGKTIAGRYET
LDFNVDYIDGPAVLTS---------EGDGWTSLCSFADRRAGSSYPVQVKDGLGTLQCRV
EGNH-IGSHNVSFSVFNKGK-SAVHKG-AWLISAKQE----LFLYQTHPEIFSVFPAGGS
LAGGTELTVTGDFFEEPVQVTAAGVPCKVKHV--SPQEIRCTTEPLGEGRRFGTPQPGNR
GLLFEVWDDA--SDLTEAGPGYRWQFVPNASSPVRFLSGAKKSFSSRLRGFFVAPQTNNY
TFWIQADGQASLYLSLSQDPKQKV-RIASLPAGNSEWSENWVKNW----SELWQPKSQKF
ELTAGSRYYLEALHHAETPSKGMRVGVQMHNTWLDPRVVNSYYTERHEIRARALHLPEVQ
LLTVSG-TGYFSISCNNTL-RMIPTNATAHQVQAAIEELLSVGCETEPTSAKILFRCGFE
KEDMENIITTGHIVSRTEPFCGRSSIHRPSQLVKTSPSTLPRYDLTKYPHVCFAHKGHMS
NILHLSVSYTNVSSCPVRRNLTCQWDF----NETDSKSWTFTCTNLWKRCVNLSVLLQDL
PANSPVSVHQIDLQSPVLQKETHGSFYLDELIIADRSVIVSQRDPKPPWPGGRIIEAVSV
VGSPPTYNVSWGVSGCGASLPLLSLSTLSPNAS---------GAGCQLLSLTIQRLQKSS
PPLGGTFHIHLAN-TVIPDVSVHISAHQLRRLLQDNVDNFTAPFFNTSDFTVTRDSSSCY
ESVWTLTWKKTAGDLPNVISV---SAENLTGLNPTVSTRVVYDGGVFIGPIFGDMLATLH
NQTQVVVMVNDVLANCSGSCSFQFSQDLTPIVRDVEYSSGEGS---QATVVLRGAGFGEE
QLALQVEVDRRSCHVTSLNQTRVVCQVPRLPVGIYPVTLLVT PHGFALGGTTGQGIFLTV
Q PKLGA-VEPPSTSELGGLKVTLRGTNLEGVNAVLFGSQPCPILEEGRNSTRIQCKVPSR
GAED-SAVHVTLIFGYKSTTVTNLFQYDPSLNPALVSLSRNRSGIA--GGEELHIGISQ-
-FANYQGSDVKVQIGDSWPQIQAQTERGVNVTLPALPAGWYNISVLINGIALTSNRVEPL
IQYLSEIFSVEPCCGSVLGGTLLTISGVGFSQNLALVSVSMDNQTCTVTRLEEETVWCLT
PPAANLSN-EDSND--ISVRVNVAISSGSFQQ AL---SANSTTTFNYQRALTPLVTAVET
EITDGSLLLSIQGINITGSVARLGHTECQLEFQWG------------SQSSTSFQCSLPL
SRLEPGTFPIQVIQRQLGYAQVTARQQSLTIT PQITSIFPSQGSICGGMLLTITGI-ALK
SRRNLTQVSLE--SNYSCEIQKSDNDSIS-----WAHPLHPQWPAEASRAL----SVTVV
VN GVRSVCLGGCILHLQEHWTPLVHLVTWK TNGTSTHMTIKGQRLAWQGDSPVVHVDNSS
ACKVTFWNET-IIKCQTACLAPGEHNISISSR KSGHACFRGTSNLFTIL PWVYQFYPRDF
STNGGGLLSLAGLALKGKRMTSVLIDHHPCFVLNI-TCVFIQCTVPPGKGTRALSLKVDG
HSYYLGTISYSEEFTPAFLSLVSTG-LLLTLTVSQVTEMDIIQVFIGDFPCSNITI----
SRSMLQCTAPLLPVGEYPVLGLDIPRGWASSSLVFISHLTVTAARHNWG-GLNGGQVYLR
GTGFSPGKTWVTVCGTSCELLGNMTVTELSCLAPCLQASLAILCGLTHSSSNCQEDRATF
IECDIQVMVGTFQQRGSVSYFYIFPPLPSCLFKVDQLAS---CVVFPISPLALGDPKVER
DEVLIYNSSCNITMETEAEMECEGANQPITAKITEIWKNWGQNTQ---------------
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-------MTGWLISLTNIEILLLAVSCLRVRIEPEEGSLAGGTWITVFFDGLE---LGLL
YPANGTQLEIHLVN--MAVPSLPRIPCDISPLF--LDLPAVMCKTRSLL--SEAHEGLYY
LEVQSGGQVAGSPSPGPGDSCTFKFSRAQTPIVYQVNPSSGVPGNLIDVYGWIVTGSLET
FDFDTEYIDSPLLLEA---------HGDEWVTPCSLVNRQTGCRYPIQEDHGLGTLQCRV
EGSY-IGSQNVSFSVVNKGK-SMVHKN-AWLVSAKQD----LFLYQTYSEILSVFPETGS
LGGRTDITIIGDFFDNPAQVTIAGIPCDIRHV--SPRKIECTTR APGRGTRLSAPQAGNR
GLLFEVGDAPEGLDLTEATPGYRWQIVPNASAPFGFWSKEG QPFRARLSGFFVAPETNNY
TFWIQADNQASLYFSRSEDPKTKV-KVASIMVGTASWFDSWEQNG---GEEIWAQKTPQL
ELLGGARYYLEAEHQGRAPSSGVRI GVQIHNTWLNPEVVNTYLREKHQIRAHAQRLPEIQ
MLTVSG-TGNFFLTWDNVSSQPIPANATAYQIQTAIEELLAVKCKLEPLSANILLRLGFE
QGP-EGSSSDGNITSGTEPFCGRFSLHQPHHLVLTPPAAQRGYRLDQYTHLCIAYKAHVY
TILRVTLSFTIGFQNTVKKNVTCDWSL----AGTSPSSWQFTCTDLWKVCVQRSLPLQPP
PVNSSVLVHQIVLLPLS---PEMGVFSVDEIFIADTNLTVSQADSGTARPGGNLVELLSV
VGSPPVYNVTSWLVGCGLELPLISASSVLPEGAEE---------GSGLVQVTTQRLQRTS
PPLGGHFRIHLSN-TEIPGVPVHISASHLQKLLQNNADDFTSRYLNVSDFTVTEALKSCY
EHVWTLSWSTQVGDLPNFIR---VSDENLTGVNPAVTARVVYDGGVFLGPIFGDMLVTPN
QNTQVVVRVNDIPAHCSGSCSFQYLEGSTPQVHAVWYAP-DDN---GLLVHITGMRFSDD
LEALQVRVNKTSCKVIFSNQTNVMCQLGLLPVGKHQLTMLVR PSGLAIHARG-GGLFLNV
E PRLDA-VEPSRAADIGGFWATIQGSSLEDVSLVLFGSQSCTINVTTSNSQRIQCKVPPL
GNDG-PIVNVTVIRGDHSVVLPMAFT YVSSLN PVIVSLSRNRSNIA--GGETLSIGMAL-
-PVNYTDLDAEVHIGDTQAQVLTWTAWGLEVVLPPLPTGLHGISVSIN RVRIGAQGVDLH
IQYLTEVF SIQPCCGSLLGGTILSISGRGFSPNSALVQVLVGNRSCEVVNSTERSIWCET
PPA------PLPPG--VPARVEVWAG GEPSPHRPLPSLVAGGFTFTYEEAATPVVTATRG
EMTHHSLRLYVEGHNLSDSVVLLGGLSCDLEPQLL------------VGNTSLSACTFPL
GSLEAGTYPLQVRQRQMGFADLPAGSQKFVVT PQITALSPTHGSTCGGTVLTVIGS-AFS
SSRRSVQVDLS--GPYSCVILSLGDQTVLCRITLSDDPLPG-----ASFTL----NVTVL
VN GLPSECLGNCTLSLCEETTPVLDAWT VNISGSLTTVLIRGQRLGITAKAPVVLVDDLL
LCTVTFFNTS-HIACWISDLAPGPHSLSIFHARYGYACS GNISRHFDILPRVFH YFPKNF
SLHGGGLLTMEGTALRARNTTLVSVGRQACLTLNL-SSDLIQCSVPAGSGSVALDLEVDG
L SYQVGVIHYSHAFTPKLLSVSHTDD-TLTLLVAGISDSLNVDIFIGVSPCVGVSG----
NHTVLQCLAPPLPAGRYQVRGYDHSRGWASSDLVLVSRVTITAVTENFG-CLGGRLVHVF
GAGFSPGNISAALCGASCQVLANTTVSAFSCLVPPLDVSLAFLCGLRLEEEDCVASSSSY
VQCDLTVTVGTERLPESWPYFYMCGESSRCLFVQDHWTE---SVFPS-LSGLLISPKVER
DEVLIYNSSCTITMETEAKMECETPNQPITAKITEIRKSWGQNTQGNFPFQFCGRWSRAH
S WFSGRRPQEGDNVTVEKGQLLLLDTNTSIL-NFLHVKGGKLIFLDPGPIELRAHAILVS
DGGELRIGSKDKPFRGKASIKLYGSAYTTPFFPYGVKFLAVRNGTLSLHGSLPEVVVTHL
RAAASAGDTVLALEDAVDWHPGDEVVVISGMGADDAEPMEEIVTVETMRGADLHLRSPLR
FSHNATENWMAGEHHVLKVMVAVLSRSITLQGNFTEERLKFLASCQGAS-SSGNLQNCLY
SKSEKMLGSRDLGARVIIQSFPEEPSQVQLEGVQLRDLGQAFREHVSSLTLVGT--LSGS
YVQGCTVWLSF-SRGLSMSRTSGLKVDSNVFYDILGHALLVGTSPEIRYI-----PSEVI
--PTGENDWPEQGNIIRNNVIIRVAGAEGLSSPEMLAPSGIYIRDPTNVVEGNQVCASGY
GYFFHLVTNQTSQAPLLSFTRNSAHSCTRSGLIVYPKFQPPWDNGTGPTLFQHFTVWGSA
GGAQI-FRSSNLRLENFQVYACRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSA
GIKTPKRWELIISNTTFMNFDLADCVAIRTCSGCSRGQGGFTVKTNQL--KFTNSSNLVA
FPFPHAAILEDVDGSLSGKNRSHILASMETLSASCLVKASFSQLVHGSVCEENVLFHRMS
IGLASAPKIPYDLTITDSKNKTTTVSYVHNTLSNLYGWMALLLDQETYSLQFD-SPWSN-
CSLQYSATFDNFAPGNYLLIVHTDMPWPHP---DILVGCGSQVGRALPSLPSPGQDQGCD
WFFHSHLRQLTYLVSGEGQIQVLLQVREGV-APTISDSTPARESSIKWSLPDAWEGVEKG
WGG--HGGTIPGSGDDVLILPNRTVLVDTDLPLLRGLYVRGTLEFPVDRSNVLNVTCMVI
AGGELRV--GTLENPLGKEKKLLIFLRASEGVFCDRFNGIRIDPGTIGVFGKVQLHSAYS
KKSWTH LGADIASGNERIIVEDAVDWRPQDKIVLSSSSYEPHEAEVLTVKEVRGHHVRIH
ERLRHRHIGSVHIMEDGRKVRLAAEVGLLTRNIQIQGDTACGGSLLVGSFRKSNGEEFSG
VLQLLN---VEIQNFGSPLYSSIELTNVS AGSWIISSTLHQSCGGGIHAAASHGIILNDN
VVFGTAGHGIHLEGQNYSLSKNLVVLMTQSAWSPVWVAGIKVNQAKDIHLHGNAVGGSER
LGFHIRGHRCSSSEVLWSDNVAHSSLHGVHLYKESGPNNCTSISGFLAFKNFDYGAMLQG
ENSMQIENITLVDNAVGLLAVVYVSSAPQCYIRNREIVLRNSVIVATSSSFDCIQDRVKP
RSANWTSADRAPSSPRGGRVGILWPVFTSEPNRWPQEPWHKV-RNGHLISGIMKLQ-GVT
FSSFVKSCYSNDLDVCIVSSSENTGIVPPITAERTRMLKIKDKNKFYFPPLQT-RKDLR-
LVCSESDCESPRKYLFKDLDGRALGLPPPVSVFLKTEGEWTGSFFN--TGTFREEQKCTY
RAPIQGYICKQTDQVILILDSADATWAMQKLYPVVSVTSGFVDTFSSINANTPCSTSGSV
SAFYSILPTREITKVCFVDQTPQILRFFLLGNKSTSKLLLAVFYHELQSPHVFLGERLIP
PTLVQSASSLLNEPIGSNYFSIMDNLLYVVLQGEEPVEIRSGVAIHLALTVMFSVLEKGW
EVMILERLTDFLKVCQDQIRLIHEIPGDESTLKTIADSKTKRKRNCPIVTCVNH-D-RAG
QRRPLMIEMSS-YRVLSPTTMDTVSKVMVIEIGDPPTMRNTGPIPSLSSNKLQSLAHQVI
TAHQIGVLENALNITVGALLV-TQSKGIIS---SGNTSSFETGNLIYIRPSALKVLVQPS
DGEVGRELTVQPQLVFLDKQNRTVESLGPPSEPWAISVSLEGTSDSVLR--GCT-WAETQ
DGYVSFSNLAVLISGSNWHFIFTVTSPP-GANFTARSRSFAVLPATPSEKSTIILAAFLC
SGVSWMALCCLVCCWFKKSKS--RKIKSEEISESQINDPKN----C-IHVLSKC------
QGTHVE-TKKEGPVMAEDLRLKLMRG-KL-NQVPHH-SLNGVSRRKLSRPAVREEG----
-GSRGEAAVPSPSTSSVALHRN-TSAPDLPVQQLCLQETESWKGAQEQVLRYHLAG--QD
QMLL-LCGDLRRERQRLQ-DQHCLGEENVNLGLSQEKAASCRATEVFCLHSVRSEAVQAA
VIKKQ---------------------

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--------------------------------------------------QLCGRWDEDS
SWPGGRQPRDGDNVTIEGGRTLLLGTATSIL-NLLQLRGGKLLFTGPGPVELHAHYILVS
DGGELQVGSPEAPFHHKAHIYLYGSLHSPPLFPYGVKFLAVRNGTLSIHGWMPKVVFTHL
KSSANASDTRLVLQEPVDWQPGDEIL-VGSSGLGDAQQQEEVAVIHSVNNLELNLRSPLR
YPHKVGEEWGNGQGLPSSAVVALISRRVVVQGNVTLERMSHLRQCANAGCRKESRSGCLY
KRSERQLGSRDLGAIVVVESFQGQASRLQLEGVQFRHMGQAFRHHGSALTSVGK--LNYS
YIRGCCVLDSF-GQGLRLSGISKLSVDSNVFYNISGHGLLLGNFSSFFFFFFSFSSYLFI
---LK--VRDWKRNKISNNIVTGLSVTDGLSNIEALSPAGIYIKAPASHIRGNTVYGAGY
GYFFHLSPEGPSKVPLLSFSENTAHSCTRHGLLVYPEYLPDS-----RVQFNNFTSWSCQ
GGAQI-FSSRNLELQHFWISACKDFGIDIVESLGNTSVSDSVLNGHLGQK---DRTCMSA
GLKTPKRYQLFISNTAFRNFNVSTCTAIRTCSGCYQGQGGFTVTAEHL--TFTNSPFQVS
FPFPHSAILEDLDGSTTGQKGSHILPSTDILAASCTASANFSQASGGSVCDSDLVFHRMA
LHLKEAPDIPYNLTVTDSRNKSNTVNYVPDTLSNLHGWMVLLLDKETYTLTFD-NPLVS-
KQLQYSVTFSNFKAGNYLLVEHKD-LPAHL---EAVVSCGTRRGQSLQLVPLYGRHRSCD
WHLDSKLGTFTYLGKCSVGVAIHISAG---V--PPLCNNFPSCAVLKWSLPETWNGVGKG
WGG--SNGSIPGPGEDVIILPNRTILVDVALPPLRGLYILGTLEFPSSSSNVLSAACVVV
LGGVLRV--GSLQHPLERDLKLLFLLRASEGIYCDRLEDINVHPGSIGVYGQVQIYSAYP
KMPWTHLGTNVAPGNERIFVEDEVDWDQGGDIVISSSSYEAHQAEVVTLKEVHGHNIRIH
DHLLHRHIGRPHDTEDGRSIPLAAEVGLLTRNVQIQSDVACAGRMLVGPFRDSSGMEFSG
ALQLLN---VQFLNFGPPHLSAIEFRNASQGSSVVSSSISGSCGAGIKAVESSGILLHDN
VVFNTTGPGIDLEGKNHSLIRSLVILSRQPAGSLNWVAGIKMNLATGVSLRGNAVAGSER
IGFHIRGQECSLAVEYCSGNVAHSSLHGIHLYQEDGFQTCTRITGFLSYKNYDYGVMLHL
GGSIIVENVVLVDNTVGLLAVVHCAYTEQCYTGKKIIELKNSIIVATSSTFDCLRDRIKP
HSADPTAQDRPPRYPLRGRVGILWPTFSSVPSQRPEHPWHKTSGHCPKAPGIMKLK-EVT
FTGFTQSCYSEDRDVCIMSNADHLGIMPLITAETSRMLHVSEKDKFYFHPTSQYVPTFKD
TMLPEKRCKGSTKALFKDLDGGVLHLEPPVSVFPKSEFEWTQFYSE--AGIYRDDSKCLF
KPSIQGYFCKQTDHALVILENLDSSVDSQRLFPVVTMTGSFMDTFTDETSHSLCYPAEHR
STLFSILPSTKLTTVCFPDLAPLAFRLYLLSGQNTTRLPLAIFFTEPLSLRVFIQGDYVS
LTPS---SFSLDAGAGANYFSFEDNLLYVLLHEKEP-EIFAGLSLLVAFTVTELLGNQLR
EAIITRRLADFLKIGHDQVRVVYNVLGSESTLQVISANASKKKYHCPNMAFCTAFQSRYS
PQEEESQPGST--QALHPPDGAGPSRVLIVELGDLPGHPRNEL----TSDSVKSLARTII
NTHQTGDLQSGLGLPVDTLMV-TQPA-------LLNGSRQHSEMCLYRRPYSISVQVQPS
DGEIEKQLPVQPKIIFLDRKGERIDKLGPPAEPWVVSAHLKDSSEAVLK--GLT-QVQVI
EGCATFSNLAVSSSGKNWRLVFTVTSPP-GVKFTVLSQPFSTFPVPTRARASMILIVILG
STASAFF-IVLSFCWFRKSKS---------------------------------------
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------TMTGWVISLMSIEVLLLSVPHLSLHIEPEEGSLAGGTWITITFDGWD---LSVL
YPNNGSRLEISLVNV--AVPALPSVPCDITPVF--LAVPVVMCQTRSLL--SQAYEGLYS
LEVRSGGQVV-----GPQDNCTFKFSKAQTPVIYQVNPPNGVPGKLIHVYGWIITGKLET
FDADAEYIDSPLVLEA---------QREKWITPCSLINRQTGNHYPFQEDRGLGILTCRV
EGDY-IGSQNVSFSVFNKGK-SMVNKS-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGGTDITITGDFFDSSSQVTTAGIPCDISHV--SPRKIECTTRAPGKGARLTAPQAGNR
GLLFEVGDAVAGLELTEATPGYRRQIVPNASSSFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASIQVGTADWFDSWEQSG---SEGTWQQKSPKL
ELLGGARYYLEAEHHGTAPSSGMRIGVQIHNTWLNPDVVTTYLREKHQISVRAQRLPEIQ
TLTVSG-KGDFSLTWDTISSQPLPANATAHQIQTAIEKLLAVKCKLEPPSANILLRLGFE
QGL-EGSSSRGDLTSGTEPFCGRFSLRQPRHLDLIPPGAQKGYWLDHYPQLCMAYKGHRS
TILRMTVSFIIGFQNIT-KTSTCDLSL----MGISPQSWRFTCTDLWDMCVYHSGNLQMP
LVKASVLVHQISLFSVA---LETGLLYLDEIIIADTNLTVSQDDSATARPGGNLVESVSV
VGSHMAYNITSWVAGCGAELPLLTARAVPSEGE-----------DSGSVQVMTQRLQKTS
PPLGGHFRIQLSN-TVISDVSVHMSAVHLHKLLQDNADDFTSRYLSAGDFTVKEDLNSCY
EHVWTLSWATQVGDLPNFIK---VSDQNLTGVNPAVAIRVVYDGGVFLGPIFGDMLAAAH
QHTQVVVRVNDIPAQCLGSCSFRYLTGATPKVHSMRYSLDGDT---SLLVYITGTGFSDD
SKSFHVVVNKTSCKVIFSNQTILVCQTDLLPVGVHQVSVLMR PSGLAVNASG-KGLLLYL
E PRLDA-VEPSRAAEIGGLWATIRGSNLEDVSLVLFGSQSCAINVTTRHSRRLQCKVPPR
GQDG-HIVDVTVFSGNHSTVLPRAFTYVSSLNPVIVSLSRNRSNIA--GGETLFIGMAL-
-LENYADLDVEICVQDTLAQAHTWTAQGLRVVLPPRLPGLHTLSVSINGISIHSKGVDLH
IWYITEVFSIEPCCGSLLGGTILNISGVGFSRDPALVWVLVGNQSCDIVDSTETSICCET
PSAPLLSS-ADS----LPVSVEV WTGNVSFIHGPAPSLVGKGFTFMYESATTPVVTAMWE
EITNSSLKFYLEGNHLSNSVILLGNLKCDLETQYF------------GGNVSLSGCAFPF
HSLEAGVYPIQVRHKDMGFANMSVVSQHFAVMPW ISTTIPMHSLACGGTVFTIMGT-PFK
SRKRSIQVDIL--GPFTHVILSLRDDTLVCQVDLVGDHLTG-----AFFTF----NITVL
VKEVDSKCQENCTVFMQEETSPVMDILAADINGSLITILMMDQKLGSTADEPIEFMDNQL
PCDLTSFNAS-HVTCHINGLTPGLHYLAVVHISNGCVLGGNVSKYFSIIPQVFHYYPKNF
SIHGGSLLAIEGTALRGQNTTSVYVGQQACLIVHI-SSELIQCIAPAGNGSVALEIEVD G
ILYHIGVIDYSDAFTPELISVSQIDD-ILTFAVAQISEAVNMDIFIGMSPCVGVSG----
NSTVVQCMVPLLPAGQYHVRGYDHSRGWASSALVFTVRAAVIAVTENFG-CLGGSLVHVF
GAGFSPGAISAAVCGAPCHVLANATVSAFSCLVRPLDVSLAFLCGLKKEEDGCEAPVHTY
VRCDLTVTVGTQTLAGSWHYLYTCEEGSQCVPVPDWWTE---PGFPS-FSGLFISPKVER
DEVLIYNSSCTITMETEAEMECETPNQPITTKITEIRKSWGQNTQGKFSLQFCLRWSKTH
S WFPGRRPQDGDNVTVEQGQQLLLDTNTSIL-NLLHVKGGKLIFMGPGPVELRAHAILVS
NGGELQIGSEDKPFQGKAQITLYGSSHSTSFFPYGFKFLAVRNGTLSLHGSVPEITVTH L
RAVGRAGDTVLALEDAVDWHSGDEVLIVSSTGVGGASLREEIVIVETVHHADLHLRAPLR
YSHDYSENWLAGKHHILKATVALLSRSITIKGNLTQERRKFLASCEKTNVVEGNLLHCLY
SKSEKVLGSRDLGARVIIQSFTKEPSRVQLKGVQFQDMGQAFQKHLSSIMVVGA--MRG S
YIQGCTVWRSF-SRGLDLGSTWGLEVDSNVFYKILGHALLIG------YI-----PWEFS
PGRKH--GWSEQGNIIRNNVIISVSGAEGLSSPEMLTPSGIYIRSPINVVEGNRVCAAGY
GYFFHLVNNQTSEAPLLSFTQNTAHFCTRFGLFVYPKFHPPWDHDTGLTMFQNFMVWGSA
GGAQI-FKSSNLHLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFTHK-V-KRLCMSA
GIKTPKRSELMISNTTFVNFDVINCVAIRTCSGCSRGQGGFTVKTNHL--KFINSPNLVA
FPFPHAAILKDLDGSLSGKDKSHILASMETLPDSCSVNANFSQIVQGSVCGEGVLFHRMS
IGF--APDVFCDLIITDSRNKTTTVNYVHDTLSNCYGWMAVLLDQETYSLRFA-DPCIN-
KSLQYSATFDNFSPGSYLLVVHTN-LPPSP---RILMRCGSRVGRSLLSLPLPAQDQGCD
WFFNSQSRQLTYLVSGEDQVQVSLQVEEGEVLPTISASKAAPKSALKWSLSATWQDVEEG
WGG--HNHTIPGPGADVLILPNKTVLVDTELPFLKGLYVMGTLEFPVDKSNVLSVACLVI
AGGEMKK----------KDQKFLIALRASEGVFCDRLNGIRIDPGTIGVYGKFQLHGAYP
KKSWTCL AADIAPGNDRIIVEDVVDWKPDDKIVLSSSSYEPHEAEVLSIREVKGHHIRVH
GRLQHRHIGSSHVTEDGKHISLAAEVGLLARNIQIQSDTSCSGTLLVGSLRKSPREEFSG
VLQFLN---VEIWNFGSPLYSSIEFT NVSSESWILSSTLHQNCGGGIRASASHGIILNDN
IVFGTAGHGIDLEGEAYSLTNNLIVLMTQSAWSTTWVAGIKVDQAKDTLLRGNVVAGSER
LGFHIQGHKCSS-EMFWSDNVAHSNLHGLHLYEKVGSDNCTGVSGFLAFKNFDYGAMVQV
ENSVKIENVTLVDNSVGLLTVVQVS-SPQDTIRNVQIVLRNSVIVATSSSFDCILDRTKP
RSASLTSTDRAPPNPKGGRVGILWPVFTSVQNQWPWEPWHKV-KNGHSVSGIMKLQ-DVT
FSSFVKSCYSDDLDICILPNSDSTGMAAPIIAERTRMFKIRDKHKFYFPPLHS-RKNLEG
VICSESDCENPRKYLFKDLDGTALGLPPPVSVFPKTEAEWTESFFN--TGPFREEQKCTY
RSSVQGFICKQTDQVVLTLNSVNVTWPIQKLHPVVSVTRGFVDTFSSINDNTLCSTSGSV
STFYSILPTRQITRVCFVDQTPQVLRFSLLGNKSTSKLLLAIFYHEIQSPRVFLGGSFIP
PTFVQSASSLLDESIGVNHFSIADNLLYVVLQGEETIEIRTDLSLHLAFSVTFSVLEKGW
EVMILEKLTNFLQIDQSQIRVTHEMPGNERTLKAFADSKAKRKRNCPTVTCASH-YRRVG
QRRPLMMEMSS-SRVFPQTTVETISKLIVIEIGDLPASKKTRQISCLSSYKLQNLAHQVI
TAQQTGVLENVLNISIGALLV-TQSKGVMG---YINASSFKDRSLIYARPYALFVLVQPS
DGEVGKELPVQPRLIFLDKQVTSHSNCRLP---FV---------LCLFT--GST-QAKTQ
DGYVSFSNLAVLISGSNWSFIFTVTSPP-GANFTARSKSFAVFPETRKERSTIILATSMG
SVVSWLALSCLVCCWFKRSK--HRKTKPEEISESQTNDQKN----Q-IHDSSKW------
QASQIE-PEKEDSRKAEDMRMQVLLG-RL-NRLPHQ-TLDGVSRRKLGHL----RA----
-AREEEAAVPAPS------TGH-TCDPGSSTQQVHPPEN----ETQEQLIRYQQAN--PD
QRLL-LGPHLSQDRQQGQ-GQSHRSADKVGVDLSQEKSTSGHATGTLCLPAAQPETI---
--------------------------

------VMPCWLFALLSVQALPLTEPHPSVRIEPKEGSLAGGTWLTVSSDDLV---RGVL
YPTDGSQLEIDLVNV--AVPSLPRIPCDVSPVL--LDLPVVTCRTRSLQ--SEAHEGLYS
LEVRSGGQVVGSSCTGSRDSCTFRFSKAQTPFVYRVDPPSGAPGELIHVHGWIITGKLET
FDSEAEYIDSPLILEA---------QGDRWITPCSLINRHTGDSYHIQEDHGLGTVQCRV
EGHY-IGSSNASFSVFNKGS-FTIIVSGAYAVLYLVAYFFFFLKKKTLAEILSVFPDTGS
LEGRTDITITGDFFDTSAQVTIAGTPCDIRHV--SPRRIECTTRAPGKGARLTAPQAGNR
GLLFEVGEAAGDIELTEDTPGYRWQIVPNASSPSRFWPREGHPFRSRLSGFFMAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-QVASVGAGTADWFDSWEQNG---DDGVWNQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQVHNTWLNPDVVPTYLLEKHQIRARAQRLPEIQ
MLNVKG-LGNFFLTWDNVSSQPILANATAQQVQSAIEELLAVKCTLDPVSANILLRLGFE
QGL-QGSSSDGVLTSATEPFCGRFSLHRPRHLVLVPLAAEKGYRLDQYPWLCIAYKGHTR
TTLRVTVSFTSGLRNVIKKNSTCNWSL----VEPSPESWQFTCTNLWDACLWPSEDLQPS
PPSNSVLVHRIDILLVA---QDTGLLYMDEIIITDTHVTVSQGASGTARSGVHLVESVSV
AGSPPVYNITSWLVGCGTELPLISACSVSTEGAEE---------GAGLFQVTAQRLQRSS
SPLGGHFLIQLAD-TVIPDVPVHISASRLHKLLQDNADDVTSRYLNVSDFTVTEDLASCY
EHVWTLSWTTQVGDLPNFIR---VSDQNLTGMSPAVAMRVVYDGGVFLGPIFGDMLASAN
QKTQVVVRVNDIPAHCQGSCSFQYLQGSTPTVHFVWYSLGHDN---NALVHLIGTGFSND
SWAIQVTVNKTNCEVISSNHTNVACQTDLLPAGIYQMSMLVR PSGLAVNASG-EGLFLYV
E PRLNA-VEPSRASEIGGLWATIRGSGLEGVNLVLFGSQSCTVNVTSSNSHRIQCRVPPR
GEDG-YIVNVTVVIGDHSAVLVRAFIYDPSLNPVIVSLSRNRSSIA--GGAVIVLGTARP
LPVNGTDMDVRVRVRDTSAQVRAPTAQGLEAVLPALPAGVYTVSVSVNGVSLHSQGVDLH
IQYITEISSIEPCSGSLLGGTVLSLSGIGLSTEPALMRVLVGKRPCDIVKLTEMNIWCKT
PPASTPPS-ADALT--VPAQVEVWVG NTSLTQAPASSLVAKGLTFAYEAAATPVVTALWG
EFTNDSLGLYVEGHNLSQAVILLGNLECDIQVQPL------------GGNMTASGCHFPL
RDLEAGTYPLQVHHKKMGFADMSAVPQQFEVT PRITAVFPMHGSVCGGTVLTVKGF-ALR
SRRRSIQVDLS--GPVTCAILSEGDHTVQCQINVVSDHLPG-----ASFTL----KVTVL
VNGLTSECQGNCTFFMQEEATPVVDVLSIDASGSVTTVLMRGQRLGTTAHEPAVLVDDRL
SCLVTFFNAS-HVACLVSDLTPGQHYLSALHTSTGYACFCNVSRHFCITPRVWDYFPRNF
SVHGGSLLTLEGTALQGQNATLVYVGAQACLTVSI-SSELIQCFVPAGNGSVALETEVD G
VSYHVGVIGLNSAFTPELLSVSQNHS-ILTFTVARISGAANVDLYIGTSPCVGVQG----
NRTVLQCLVPSLPAGEYPVRGYDHNRGWASSVLILTLRAAVTAVTGNF-GCPGGRLLHVF
GAGFSPGNISAAVCGEPCQVLTNATVSAFSCLVLSLDVSLAFLCDLRHAEDSCAVISHTY
VQCDVTVTVGTERLPGSWPYLYFCEESAQCLFVPDGWTE---SAVPS-FSGLFISPKVER
DEVLIYNSSCNITMETESEMECETPNQPITTKITEIRRSWDQNTQGDFSFQLCRRWSRAR
TWFPRRAPQDGDNVTVEKGRLLLLDGRSSVL-NFLHIKGGKLIFMEPGPIELRAHSILIT
DGGALQIGSKDKPFHGRAQITLYGSSHSSPFFPYGIKFLAVRNGTLSLHGSTPEVIVTHL
RAAARARDMVLALEDAVDWHPGDEVVIISGTGAQDAKPAEEIVIVESVYGSDLRLRSPLR
YSYNFTESVLGGKRHVFRATVALLSRSITIGGNLTMERMQHLTSCLEVRASEG-RKHCLY
SKSEKTLGSRDLGARVIIQSFLEEPSLVQLKGVQFRDMGQAFRKHVSSLTLVGA--LQGS
YIQGCTVWGSF-SRGLSMFRTWGLRVDSNVFYKILGHALLVGNYTS----------WKTV
AGRET--DWSEQGNIIRNNVIISVSGAEGLSNVEMLAPSGIYVRSPTNVIEGNGVCAAGH
GYFFHLATSWASQAPLLSFAQNTAHFCTRFGLFVYPKFQPLWNKETGPTVLQDFTVWEST
GGAQI-FRSSNLRLKNFQVYSCRDFGIDIVESDANTSVTDSVFLGHFIHK---GNLCMSA
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSGCSQGQGGFSVMTQQL--KFTNSSNVVA
FPFPHAAVLEDLDGSVSGQDGSHILASMQTLASTCSANASFSQLVPGSVCGEGVLFHRMS
IGLANDLGVSNNLTLTDSRNKTTTVNYVRDTLSNQYGWMALLLDQETYSLHFE-IPWTN-
KSLQYSATLDSFAAGNYILLVHTN-LPPYP---TILITCGSQAGQSLQDLPWPGQDKGCD
WFFNSQLRQLTYLVSGQGQVKVFLQVKEGV-PPTISASTLAPGEALKWSSPETWQDVEEG
WGG--YNHSIPGPGDDVVILPNRTVIVDTDLPLLKGLYVMGTLAFPVDRSNVLSVACLLI
AGGELRV--GTLENPLEKEQKFLINVRASEEIFCDRFYGIRIDSGTIGIYGKVLLHSAYS
KKPWAH LGADIASGNERIILEEAVDWQPGDKFVLSSSSYEPHEAEVLTVREVKARDIRIR
ERLKHRHIGSSHVTEDGRHIRLAVEVGLLTRNIRIQSDTRCRGSLLVGSFGKSNREEFSG
VLQLLN---VEIQNFGSALHSSIEFLNVSWGSW VMSSSLHQSCGGGIHASASHGIILNDN
IVFGTYGHGIDLEGKNYSLSNNLILLTMQPDGSSTWVAGIKVNRANEVTLQHNVVAGSER
VGFHVRGHGCSS-EVPWSGNVAHSSLHGLHLYKESGPNNCTGISGFLAFKNLDYGVMVHT
ENSLEMENITLVDNAVGLLATVHVSSDLLSSVQNVQIVLRNSVIVATSSSFDCIQDRVKP
SSANLTSTDRAPSNPRGGRVGILWPVFTSEPNRWPQEPWHKV-RNGHSISGIVKLQ-DVT
FSSFVRSCYSDDVDVCILPNEGSAGITYPITAERTRMLRMKDKNKFYFPPSHP-RY----
VIYPESECENPRKYLFKDLDGRTLGLPPPVSVFSKTEAEWTGSFFN--TGIFREEQKCTF
RAMIPGFICKQTDHVVLVVDNVDTTWTTQKSYPVVSVTSGFVDTFSGMKTRTSGCTRTSA
TTFYSIVPTGQVTRVCFVEQTPQRLRFLLLGNRNATKLILAVFYHEIQSPQVFLRERFVP
PALMESASPLLEESAGANVFNLMENLLYVVLQGEEPVDIHTSTSIHLAFTVEFSVLEKGW
EVAMLERLASFLRLGQNQIRFKHQIPGNEDTLRTIADSWAKRKRTCPTITCGSR-YRRSG
QRRPLMTDVNS-YKFSPPNTLDMISKVIVIEIGDPPTVRKSGLVLDLPRNRLQNLAHQVI
TAQQTGVLENALNVTIGALLV-TQAEGVTG---YRNASSSRAGNIIYVRPWTLSVLVQPS
DGEVGKELSVQPQLVLLDEKNRRVETLGLPSEPWTISASLEGVSDSVLK--GNT-QVETQ
AGYVSFSNLAVLISGSNWRFVFTVTSPP-GNF--TRSKPFAILPVTGKERSTVILAVSLS
SVVSWLTLICLLCCWFKRSKN--RKIKPEDMSESQVNEQKN----H-IQFSSKR------
PGSRVE-TRKQDAGMGADVRMKVMLG-RA-K----Q-PVDGVFRRQVSRRPFSE------
----DEAVAAAPRIAR----GH-TCAAASPAHQSALQEAGSWQEPREQLGRYQLAG--QD
QLLV-LCPDLGQERQRWQ-EPGQMNQRSGCSGPSQER-GSCVAPETLCLHSSPPETTQ--
--------------------------

-------MIVWLISLMSIEILLLAGPALSFHIEPKEGSLAGGTWITVIFDGLE---LEQL
YPTNGSQLEIHLVN--VAVPALPSIPCDVSPVF--LDLPVVMCRTRSLL--PEVHEGLYY
LEAHAGGQVVGSPSPGLQDCCTFKFSREQTPIVYQVTPPSGVPGKMIHVYGWIITGRSET
FDFDAEYIDSPLILEA---------QGDKWVTACSLINRQTGSCYPLQENHGLGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SMVHKN-AWLVSAKLD----LFLYQTYSEILSVFPETGS
LGGKTDIIITGDFFDNPALVTIAGVPCDIRHM--SPRKIECTTRAPGKRARLTAPQAGNR
GLLFEVGEAVEGLDLTVATPGYRWQIVPNASSPFGFWFKEGQPFRARLSGFFVAPETNNY
TFWIQADNQASLYFSQSEDPRMKV-KVASIRVGTADWFDAWEQDR---NEGVWQRKTPKL
ELVGGTRYYLEAEHYGRTPSRGMRIGVQIHNTWLNPDVVSTYLREKHQIRVRAQRLPEIQ
MLTVSG-RGSFFLTWDNVTSQPIPENATAHQIQTAIEELLAVKCKLEPLSANILLWLGFE
QGP-EGSSFEGDLTSGTEPFCGRFSLHQPRRLVLTPPAAQKDYWLDRYTHLCIAYKGRMK
NILKVTVFFTTDFQNFIKKNITCDWNL----VGTRPNSWQFTCTDLWETCVHHSMYLQPP
LVDSPVLVHRIDLFPLS---QETSGFYVDEIIIADTNITVSQADSETAHPGGNLVESLCV
VGSPPVYNISFWLVGCGQELPLITASIVPTGGEAR---------RSGLVQVTTQRIQKTS
PPLGGYFHIQLPT-SVIPDVPVHISASHLRKLLQNNADNFTSRYLNSSDLTVMEDLKSCY
EHEWTLSWSSQVGDLPNFIR---VSDANLTGVNPAATVRVVYDGGVFLGPVFGDMLVTAN
QHTQVVVRVNDIPAHCSGSCSFQYLEGSTPQIHSAWYSLDGDI---SLLIYIFGINFSGD
PQALEIMVNKTNCKVIFSNQTNVICQTDLLPVGMHRLFMVVR PFGRAINTSG-EALFLSV
E PRLDA-VEPSRAAEIGGLWATIQGSGLEDVSLVLFGSQSCAINITTSNSRRIQCRVPPR
GKDG-PVVNLTVVSGDHSAVLPMAFTYVSSLNPVITSLSRNRSNIA--GGDTLFIRMAL-
-LVNYTDLDVEVCIQNTLAPAHVQMPQGLEVVLPPLPAGLYSISVSINGISIRSPGVDLH
IQYITEVFSIEPCCGSLLGGTILSISGIGFIRDPTLVWVFVGNRSCDILNSTETVIWCET
PPAALLPD-SNI PA--IPVPMEIWAGNVSFARES---LLNLSFTFLYEAAMTPVVTAMRG
EIINNSLRFYVEGNNLSNSVILLGVSHCDLETQTL------------RNNVSLSGCSFPL
HSLEAGFYPLQVRQKQMGFANMSAVPQQYVIT PWIMAISPTHGSACGGTVLTVRGL-ALS
SRKRSVQVDLL--GPFTCVILSLGHQTILCQINKVNDSFPD-----VSFTL----NVTVI
VNGLP SECQGNCTLFLQEETT PIVDSLTTNISGSLTMVLIRGRKLGITAVEPMVFVDDHL
PCIVTFFNAS-YVICWISDLTPGLHYVSVFHA RNGYACFGNVSRHFYILPQVF HYFPKNF
SIHGGSLLTVEGTALRGKNSTLVYVGQQACLTVSI-STELIQCIVPAGNGSVGLVIEVDG
LS YQMGVIGYSSAFTPRLLSISQTDD-VLTFAVAQVSGAENVDIFIGMSPCVGISG----
NHTVLQCVVSSLPAGEYPVRGYDRMRGWASSVLVFTSTATISGVTENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCQVLANATVSAFSCLVLPLNVSLAFLCGLKHSEESCEASSSTY
VQCDLTVTVGTETLPQSWPYLYICEESPQCLFAPDHWTE---STFPW-FSGLFISPKVER
DEVLIYNSSCNIAMETEAKMECETPNQPITAKITEIRKSRGQSTQGNFSLQFCLRWSRT H
SWFPERVPQDGDNVTVENGQLLLLDTNTSIL-NLLHIKGGKLIFMDPGPIELRAHAILIS
DGGELRIGSEDKPFQGKAEIKLYGSSHSTPFFPYGVKFLAVRNGTLSLHGLLPEVTFTHL
Q AAAYAGDTVLALEDAVDWHPGDEAVIISRIGVGGAKPMEEIVIVEAVHNTDLYLRSPLR
YSHNFTENWVAGVLHILKVTVVLLSRSITIQGNLTAERMKHLASCQEASDSEGNLQDCLY
SKSEKMLGSRDLGARVIVQSFPEEPSRVQLRGVQFRDLGQAFRKHVSALTLVGA--MRDS
YVQGCTVWSSF-NR GLSMSMTLGLKVDSNIFYNILGHALLVGTDMDIKYI-----SWEAA
PEKKP--DWSEQGNIIRNNVIISISGTEGLSSPEMLTPSGIYILNPTNVVEGNRVYVAGL
GYFFHLVTSQTSQAPLLSFTQNIAHSCTRYGLFIYPQFQPPWDDGRGPTLFQNFTVWGSA
GGARI-SRSSNLHLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSA
GIKTPKRWELIISNTTFVNFDLTDCVSIRTCSGCSRGQGGFTVKTNQL--KFINSPNLVA
FPFPHAAILEDLDGSLSGRNRSHILASMETLSASCLVNLSFSQIVPGSVCGEDVIFHHMS
IGLANAPNVSYDLTITDSRNKTTTVNYVRDTLSNLYGWMALLLDQETYSLQFE-TPWIS-
RSLQYSATFGSFAPGNYLLLVHTV-LWPYP---DILVRCGSQEGRSLPSLPLPGQDQGCD
WFFNTQLRQLIYLVSGEGQVQVTLQVKEGV-PPTISASTSAPESALKWSLPEAWTGIEEG
WGG--HNHTIPGPGDDILILPNRTVLVDTNLPFLKGLYVMGTLEFPVDRSNVLSVACMVI
AGGELKV--GTLDNPLEKEQKLLILLRASEGIFCDRLNGIHIDPGTIGVYGKVQLHGACP
KKSWTRLA ADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEILTVKEVQAHHVKIY
ERLKYRHIGSVHVMEDGRCIRLAAEVGLLTRNIQIQPDISCRARLLVGSFRNSSSKEFSG
VLQLSN---VEIQNFGSPLYSSIEFTNASAGS WIISSSLHQSCSGGIRAAASHGIILNDN
IVFGTVGHGIDLEGQNFSLSNNLVVLMTQSAWSTVWVAGIKANQAKDINLYGNVVAGSER
IGFHIQGHRCSSPEARWSDNVAHSSLHGLHLYKENGLDNCTGISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNSIGLLATVYVSSVPKSHIENVQIVLRNSVIIATSSSFDCIQDRVKP
RSANLTSSDRAPSNPRGGRVGILWPIFTSEPNWWPQEPWHRV-RNGHSTSGILKLQ-DVT
FSNFVKSCYSDDLDICILPNVENTGIMHPIMAEGTRMLKIKDKNKFYFPPLQA-RKGLGI
LVCPESDCENPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
RALIQGYICKQSDQAILILDNADATWAMQKLYPVVSVTRGFVDTFSSVNADAPCSTSGSA
STFYSILPTREITKICFVDQTPQVLRFFLLGNRSTSKLLLAVFYHELQNPRVFIGESFIP
PIMVQSTSSLLDESIGSNYFSILDNLLYVVLQGQEPIEIHSGVSIHLALTVMFSVLEKGW
EIIILERLTDFLQVSQDQIRFIHEMPGNEATLKAIADNKAKRKRNCPTVTCASP-Y-RVG
QRRPLMTEMSS-YRVPSPTIMETASKVIVIEIGDLPTIRSTRLISYLTSNKLQNLAHQII
TAQQTGVLENVLNMTIGALLV-TQPKGVTD---YGNASSFKTGNFIYIRPYALSVLVQPS
DGEVGKELTVQPRLVFLDKQNQRIESLGPPSEPWAISVSLEGTSDPVLK--GCT-QAESQ
DGYVSFSNLAVLISGSNWHFIFTVTSPP-GANFTARSRSFTVLPAAPSEKSSIILAVSLC
SVASWLALCCLVCCWFRKSKS--RKIKSEDISEFKTNDQKS----H-IHMSSKH------
PRS-QE-TKKEDTMMGEDMKIKVIMD-KV-NQLPHQ-SLNGVSRRKVSRRAVREEG----
-SSREEDVVPAPRIISITSQGH-TCVPGSPDQQIYLQEAGNWKEAQEQLVSYQLAG--QD
QRLL-LCPDLRRERQQLQ-GQSQLGQEGGSVGLSQEKKASGGATQASCPHLVHPETIQEQ
L-------------------------

-------MTAWLISLMGVEALLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGVL
YPNNGSQLEIHLVNTNMVAPALPSIPCDVFPVF--LDLPVVTCRTRSLL--SEAHEGLYS
LEAYFGGQLVSSPSPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMVHKK-AWLISAKQD----LFLYQTHSGTIPLYEVPLP
LCLTQR---------------WPLLPYLLNHVSPLPGKIECTTSARSKDADAFQPILSNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQLFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRAQAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
GGL-EVSNSDGDLTSGTEPFCGRFSLRQPQHLVVTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWS----LTRTNPKSWQFHCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLVPLV---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLATTRRQQRTS
PPLGGHFRVQLPN-TVISEVPVQISAHHLHQLLQNNADDFTSRYLNASDFSVKEDLYTCY
ERVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKMNCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-HIVNVTVIRGNHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAR-
-LVNYTDLDVEVHIQDALALVHTQSAWGLEVALPALPAGLHRISVSINGISIHSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRSFAHGPSPSLVGNGFTFMYEAAATPAVTAMQG
EITNSSLSLRVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSVPL
HSLEAGIYPLQVRQKQMGFANMSAVPQQFAVTPRIMTIFPSQGSACGGTILTVRGL-LLN
SRTRSVRVDLS--GPFTCEILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGITSECH GNCTLFIREEASPVMDT LSTNTSGSLTTVLIRGERLGTTADEPMVFVDDQL
LCNVTFFNAS-HVVCQTRDLAPGPHYLSVFYTRNGYACSG NVSRHFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIRCIVPTGNGSAALEIEVD G
LWYHIGVIGYSNAFTPELISISQSDG-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKHEEDSCEAARHTY
VQCDLTVAVGTEQMLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFVSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQSLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDTVLALEDAVDWHPGDEVVIISGTGVEGAKPMEEIVTVETVQDTDVYLKSPLR
YSHNFSENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIIQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRSSF-SRG LSMCGTLGLKVDSNVFYSILGHALLVGTCMEMRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGITLFQSFTVWESA
GGAQI-FRSSNLRLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRRELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFINSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLASAPEVSYDLTMTDSRNKTTTVNYVRDTLSNLHGWMALLLDQETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILWVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYS
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSEGSWIISSTLHQSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHKCS-CGLLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHI
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
LSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSIFPKTEAEWTASFFN--AGTYREEQKCTY
RFLMQGFVCKQTDQVVLILDGADATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSSVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFLREIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVS
QRRPLMMEMNS-YRSSPPTTVETMSKVIVIEIGDSPTVRSTGMISSLSSNKLQSLAHQVI
TAQQTGVLENILNMTIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYVLSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSQSFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKC------
RESQ-G-PKKEDTVVAEDMRMKVMLG-RL-NQCPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHGH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL-------QERQQLP-GQSWLSKQSGRLGLSQEKKASCGATEAFCLHSVHLEAIQEQ
L-------------------------

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-------------------------------------MRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSDD
SQFLQVTVNKTNCKVIFSNQTNVVCQTDLLPVGVHRILMLV RPSGLAISATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-HVVNVTVIRGNHSAVLPRAFTYVSSLNPVIVTLSRNTS-----------------
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---------------------------------------------NIAG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKHEEDSCEAARHTY
VQCDLTVAVGTERMLESWPYLYICEESSQYLFVPDHWAK---SMFPS-FSGLFVSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
SWFPERLPQDGDNVTVENGQSLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTRL
RATAHARDTVLALEDAVDWHPGDEVVIISGTGVEGAEPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIIQSFSEEPSQVQLKGVQFRVLGQAFHKHLSSLTMVGA--MRES
FIQGCTVRSSF-SRGLSMCGTLGLKVDGNVFYNILGHALLVGTCMEMRYI-----SWEAI
YGRKY--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPSWDNVTGITLFQSFTVWESA
GGAQI-FRSSNLRLKNFQVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKKWELMVSNTTFVNFDLINCVAIRTCSDCSRGQGGFTVKTSQL--KFINSSNVVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGQVVHGSACGGGVLFHRMS
IGLANAPEASYDLTMTDSRNKTTTVNYVRDTLSNPHGWMALLLDQETYSLRSE-KLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILWVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYP
KNSWTHLGADIASGNERIIVEDAVDWLPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGSVHVTEDGPHIRLAAEVGLLTRNIQIQPDISCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSEGSWIVSSTLHQSCGGGIHATASRGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHRCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
LSANLTSTDRAPSNPRGGRIGILWPIFTSEPNQWPQEPWHKV-RNRHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSIFPKTEAEWTASFFN--AGTFREEQKCTY
RFLMQGFICKQTDQVVLILDGADATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGLV
STFYSILPTRQITKVCFMDQTPQALRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFISEIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVG
QRRPLVMEVNS-YRSSPPTTVETMSKVIVIEIGDSPTVRSTGMISSLSSNKLQNLARQVI
TAQQTGVLENILNMTIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYVLSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFFNLAVLISGSNWHFIFTVTSPP-GVNFTARSQSFAVLPVTKKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKC------
RESQ-G-PKKEDTVVAEEMRMKVMLG-RL-NQCPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHGH-TCAPGDPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL--LSRPQTREAAVA-RAKLAE-----------------------------------
--------------------------

-------------------------PGLILHIEPEEGSLSGGTWITVIVDGLE---LDLL
YPSNGSQLEINLVNV--AMPALPIIPCDVSPSF--LDLPLVMCQTRSLL--SEAHEGLYY
LDVYSGGQLVSSLSPGPCDSCTFKF-KAQTPIIYQVNPASGVPGKLIHVYGWIITGRLET
FDFDAEYIDSPLTLEA---------QGDQWFTPCSLINRQTESSYSVQEENGLGTLQCRV
EGHY-IGSQNISFSVFNKGX-XXXXXX-XXXXXXXXX----XXXXXXXXXILSVFPETGS
LGGGTDITVTGDFFDNPAQVIIADIPCDIRHV--SPRKIECTTRSPRKGTRLTAPQAGNR
GLLFEVGDADAGLDLTEATPGYKRQIVPNASSPFGFWSKEGQRFRARLSGFFVAPETNNY
TFWIQADSKATLYFSWPDDPRTKV-EVAFIRVGTADWFDSWEQNR---NEETWHQKTPKL
ELLGGVKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVSTYLREKHQIRARAQRLPEIQ
MLNVSG-SGNFFLTWDSVSSQPVPANATAHQIQTAIEELLAVKCKLEPISANILLRLGFE
QGL-QGSSSDGDLSSAVEPFCGRFSLQQPRHLVLTPPAGQKSYLLDQYTHXXXXXXXXXX
XXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXWRFTCTDLWETCVRLSGYLQPP
PANSSVLVQRIDLFPLA---QDMGLFYVDEIIITDTNVTVSQADAGTARPGGHLVESLSV
VGSFPVYNVTFWSAGCGTELPVITASSLQAEGADE---------VSELIQRTTQRLQKTS
SPLGGHFQIQLSN-TVIRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXLPIFIK---VSDENLSGVSPAVTAHVLYDGGVFLGPIFGDMLVTSN
QYTQVVVQVKDIPAHCSGSCSFQFLQGSTPQVHSVEYSHXXXX---XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX
XXXXXX-XXXXXXXXXXGFWATIRGSGLEDVSLVLFGSQSCAINVNTSNSQEIQCKVPPR
GKEE-PIVNVTVLSRNHSAVLPGAFM YISSLN PVILSLSKNRSNLA--GGDTLFIGTTL-
-LENCAELDIEVRIQDTRAPLYAQTAQGLEVVLPPMPPGLHRIAVSINGLSIRSQGVDLY
IQYL TEVFDIEPCCGSLLGGTILSISGVGFSQDPALVHVMVGNQSCDTVNSTEEGIWCET
PPAPLLPG-SDAVN--VLAAVRVWVSNMSFP NRLLPGSGEKGFTFLYEAAATLVVTALRA
EATNNSLWFFVEGDTILNSVLLLGSLHCDLEAQSF------------RNSMGMSGCCFPL
QSLEAGIYPLQVHQKQMGFANMSAVLQRFVVA PQIMAIFPTQGSLCGGTVLTVMGL-ALS
SRRMSVEVDLS--GPFTCAILRVSSETILCQVNLMGHPLLG-----ASFAV----NVTVL
VNELTSRCQGNCTLFLREETTPAVDAWTSNVSGALTSMLIKGQRFGTAADELMVFVDDHI
PCDKTFFNAS-QVACQLSGLTPGLHSLSVFHKRSGYACWRNVSRHFYISPQVFHYFPNTF
GLNGGGLLTVEGMALKGQNATSVYIGQQSCLSVNI-SARLIQCIVPAGNGSVALEIEIDG
HLYHVGVIGYSKAFTPELLSVSQIDD-VLTFVVAQITEAVHVDIFIGMSLCVGVSG----
NRTVLQCSVPTLPAGEYRVRGHDRTRGWASSVLVFTSRVTVTAVTENFG-CLGGRLVHVF
GAGFSPGNISAAVCGAPCRVLDNATVSAFSCLVLPLDVSLAFLCDLKSGNENCEASSHTY
VQCDLTVAVGTERLPKSWPYLYICEKCSQCLSESDPWAE---SNLSS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETRNQPITAKITEIWKSRGQNTQRNFSFQFCQRWSRAH
SWFPQRVPQDGDNVTVESGQLLLLDTNTSIL-NLLHIKGGKLLFMDPGPIELRAHFILVS
HGGELRIGSEDRPFQGKAQIKLYGSAHSIPFFPYGVKFLAVRNGTLSLHGPLPEVTVTHL
RAAARAHDTVLALEDAVDWHPGDEAVIISGVGVEGARPVEEIVVVEAVQDADLHLRSPLR
YSYGFAENWVAGRHLVFKATVALLSRSITIRGNLTEERMRHLASCQGNSASEGNSQDCLY
SKSEKIMGSRDLGARVIIQSFPEEPSRVQLKGVQFRDLGQAFQKRLSALTLVGA--MRDS
YMEGCSV-NSF-SRGLSMCRTLGLKVDSNVFYRNXXXXXXXXTCMEMGYV-----SWEPL
LRRKH--GWSEQGNTVRNNVIISVSGAEGLSSPEMLTSSGVYIRHPSNVVEGNSVCAAGF
GYFFHLATRKTSQAPLLSFTQNIAHSCTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX-XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXGSLCMSS
GIKTPKRWELMIANTTFVNFDLTDCVAIRTCSGCVRGQGGFTVKAKQL--KFPFSPNIVA
FPFPHAAILEDLDGSLSGKNGSRILASMETLPDSCVVSASFGEMIHGSVCGENIIFHRMS
IGLADVPDVPYDLTVTDSRNKTTTVNYVPDTLSNPHGWMALLLDQETYTLRFG-TPWTN-
RPLQFSATFDNFASGSYLLLVHAD-MPPNP---DILITCGSRMGWPLSALPAPGQDQSCD
WFFDSHLRQLTYLVSGEGQVQVTLQVKEGV-SPTISVSTSAPESAFKWSDPETWQGVEEG
WGG--YNNTIPRPGDDVLILPNRTVIVDIDLPLLKGLYVKGILEFPVDRSNVLSVACMVI
AGGELKVXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXVYGKVQLYSTYS
KKSWTRLAADIASGNERIIVKDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVTGHYIRIQ
ERLKHRHIGSVHVIEDGRYVPLAVEVGLLTRNIQIQSDISCRGRILVGPLGKLSREEFSG
VLQFLN---VEIQNFGSPQYSSVEFMNVSGGSWMISSAVHKSCGGGIRAAASHGIILNNN
IVFGTAGHGIDLEGQAYSVTNNIVVLTTQSVWSTVWVAGIKVNKAKDINLHGNVVAGSER
LGFHIQGHRCLLYEVLWFDNVVHSSLHGLHLYKESGLDNCTKISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNAVGLLAVVFVSSAPQTSTENVWIALRNSVIVATSSSFDCIQDKVKP
RSANLTSTNRAPSNPRGGRVGILWPGFTSEPNRWPQEPWHRV-RNSHSIPGIIKLQXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX--XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXCFVDETPQVLRFFLLGNENTSKFLLAVFYHELQRPHVFIRENFIP
PTVVQSPSSLLDESVGANHFSIMDNLLYVVLQGKEPIEIRTGVSIHLAFTVMLSVTEEGW
DIVILQRLTDFLQIGQDQIRIIHEMPGNEEMIRAIADSRAKRRRNCPTVACASH-FRRVA
LRRPLMIEMNS-YRVKPPTTVETASKVMVIEIGDLPVPRDMGLIPSLSSNKLQDLTHHVI
TAHQTGALGNILNVTIGTLMV-TQSKEVFD---YGNTSSPQTGNLMYTQPWVLVVLVQPS
DGEVGKALPVQPQLVFLDKQNQRVETLGAPSEPWAISAFLEGTSDSVLK--GCT-QAETQ
DGYVSFSNLAVLISGSNWHLVFTVTSPP-GVNFTARSKSFAVLPRTRPEKSAIILSASLC
SAVSWLALCCLVCCWFKKSKSQXXXXXXXXXXXXXXXXXXX--------XXXXX------
XXXXXX-XXXXXXXXXXXLRMKIMLS-KL-SQLPHQ-SLNGVSRRKVIHRAAQEGG----
--SREEATVSAPSTVSATSQGH-T------------------------------------
------------------------------------------------------------
--------------------------

------VMPAWLIALLSMKVLLLADRYLSFQIEPSEGSLAGGTWITVAFDGLE---KSVL
YPHNGSQLEMDLVNV--AVPTLPRIPCDVHPVF--VDLPVVTCQTRSLL--SEAHEGLYS
LEIRSGEQLLSNRCPGSLDGCTFKFSKAQTPVVYHVSPPSGVPGEVVHVYGWIITDQLET
FDPDVDYIDSPLILEA---------GRDKWLTPCSLVNRQTGSCFPIQEENGLGTVQCRV
EGDY-IGSQNVSFSVFNKGR-STVHKD-AWLISAKQD----LFLYQTYAEIISVFPKVGS
LGGRTYITITGDFFDPSAQVTIAGIPCDIRHV--SPRKIECTTRAPGRGARLTTPQAGNR
GLLFEVGDAAEDVELTEATPGYRWQVVPNASSPSGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSPASLHFSFSEDPRTKV-EMASVGVGTVDWFDSWEQKG---NEGSWQQKTTKL
ELRGGAKYYLEAEQHGIAPRRGMRIGVQIHNTWLNPDVVNTYLLEKQQIRAQAQRLPEIQ
MLNVSA-RGSFFLTWDNVSSQPVLANATAQQMQTAIEELLMVKCHLEPVSAQVLLRLGFE
QGL-KGSSSDAVLTSSTEPFCGRFSLGQVRHLILNPSADKNGYQLNQYPYLCSAYRGRIN
GTLAMTVSILFDFENIT-KNSTCDWSL----TEPLPESWQFACINLWDTCVRCSEDLQSS
PANTPLLVHRIDILATA---PEAGLLYLDEIILADTNVTVSQADPGTARPGGNLVESVSV
TGFPPVYSIAFWLVACGSELPLITACYMPAEGTGE---------RSELTEVTAQRLQGTS
PPLGGHFFLQLSD-TVIPDVPVHMSSRQLQKLLQDNADESTSGYLNVSDFTVTKELNSCY
EHVWTLSWTTQIGDLPNFIS---VSDQNLTGVNPAVTARVVYDGGVFLGPIFGDMLATPN
QETQVVVQVNDIPAHCSGSCSFQYLQESTPSVDYVWYSPGCDV---NLLVYFTGTGFPRD
SQSLQVTVNKTSCEVIFSNETSVVCEMDLLPVGVYQVLMLVN PSGLAVNGSG-EGLFLLV
K PRLVA-VEPATAAEIGGLWVTIQGSSLEGVSLVLFGTQSCAIEVIRSNSQQIQCKIPPR
GNDG-YTVNVTVISGDHSTVLPRAFSYVSSLNPVIVSLSRNRSNLA--GGEILFLGMAQ-
-LVNYTGLDVLVRVQDTSAQVLTQTAWGLEVVLPPMLAGIHMISVFINGVNIHSQGVDLH
IQYLTEVLSVEPRSGSLLGGTVLSLSGVGLGRDPALIWVLVGSQPCGMVNLTDVNAWCET
PPAVLPPG-ADVLT--VPASVEIWVGNTSFLHGA--SLVGKGFTFMYEAATTPVVTAMWG
ELTNNSLGFYVQGKNLSDSVILLGTLKCDLEVQSF------------VDNVSLSGCSFPL
CSLEAGIYSLQVLHKWMGFANMSAVPQKFELSPRIMAIFPTHGSVCGGTVLTVKGVVAFS
PRRRSVHVDLS--GPFACVILSLGVHTVLCQTKLVGDHFPE-----MSFAL----NVTVL
VNGLASKCEGNC TLFMQEETTPV VDALTTSINGSLTTLLMRGQRLGTTDAEPTVFVDDHL
HCSTSFFNTS-HIACQMSDLIPGLHYLSVVHT SNGYACLDHVYRSFFIVP QVFDYFPKVF
SIHGGSLLTIKGTALRGWNATSVYIGQKTCVSVNI-SSELIQCIIPAGNGSVALEIELD G
ALYHIGLVGYSSVFTPELLSVSQRHD-ILTFTVAQISGPANVDIFIGMSPCAGVSG----
NSTVLQCMVPLLPSGEYPVTGYDHNRGWASSALILELRAHVMSVTANF-GCLGGRLLHVF
GAGFSPGNISAAVCGAPCQVLANATVSAFSCMVLPLDVSLAFLCDLRHAEDSCEVGSHTY
LQCDLTVAMGTKRLPGSWPYLYLCEESSQCLLAPDHWTE---PAFPS-FSGLFLSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPIIAKITKIQKSRGQNTQGSFPFQFCRRWSRPH
S WFPQRVPHDGDNVTVETSQLLLLDVNTSLL-NVLHIKGGKLIFMEPGPIELRAHSILIT
HGGELHIGSEQKPFQGKAHLKLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSVPQMTVTY L
RAAARAGDTMLVLEEGVDWHPGDEAVIIGGMGIEGAGPMEEVVVVEAVHNADLHLRTPLR
HSYNFTGNWVAGKNHTLRATVALLSRNITIQGNLTLERLKLLHSCQKANAAEGNLKHCLY
SKSEKMLGARDLGARVIIQSFPEEPSFVKLQGVQFRDLGQAFHKHQSSLTLVGT--MIGS
YLQSCSVWGSF-SR GLSMHRTWGLRVDSNIFYKIAGHALLIGTYMDRMFT-----TSETI
IGGKN--DWWAQGSTIRNNVIISISGAEGLSSPEVLAPAGIYTLSPTNVIEGNRVCAVGY
GYVFHLMTRQTSQAPLLSFKLNTAHSCTRYGLLIYPKFQPTWNNDTGLTLFQDFMVWGSA
GGAQI-FRSNNLHLKNF QVYACRDCGIDILESDANTLVTDSFLLGHFTHK---GSLCMSA
GIKTPKRWELMISNTTFVNFD-LNCVAIRTCSGCSQGQGGFTVKTREL--KFENSPNLVA
FPFPHAAVLEDLDGSLSGKNGSHILPSMETLSDTCSANASFSHIAPGTICPDGVLFHRMS
IGLDKALGVPKDLIVTDSRNKTITVNYVSDTLSNYYGWMALLLDQETYLLQFP-NHWMD-
RSLQYSATFDRFASRNHLLLLHRD-LPPHP---DILIRCGSRVGQSLPSPPLPSHDRGCD
WFFNIQSRQLTYLVSGEGQVQVFLQVKEGV-PPTVSASTSVPDSALKWSLPETWQDVTKG
WGG--YNQTIPGPGDDVLILPNRTVLVDTDLPVLRRLYVMGTLEFPADRSNVLSVACLLI
AGGELKV--GSLKNPLEKEQRFLVLLRASEEIFCDHFDGIHVDPGTIGVYGKLHLHSAYP
KKSWVH LGADFAPGNERIIVDDVVDWQPHDKIVLSSSSYEPHEAEVLTIKEVKGHHIRVC
ERLRHRHIGSAHIMEDGQHIPLAAEVGLLTRNIKIQSDSSCRGRLLVGSFRKSSREEFSG
VLQLLN---VEIQNLGSPLYSSIEFMGVSAG SWVISSTVHQSCGVGIHASASHGMVLNDN
VVFGTSGHGIDLEGQNYSLTNNLVILTMQSARSSPWVAGIKVNYAKDIILHGNVVAGSER
LGFHICGHGCSS-DVLWSDNVVHSSLHGLHLYKKHEPANCTGVSGFLAFKNFDYGAMVQT
ENSVVLQNITLVDNTIGLLAVAYVSSAPLSSIQAVQIVLRNSVIVATSSSFDCIQDRRAP
QSANWTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKL-RSGHAVSGIIKLQ-DVT
FSNFVKSCYSGDLDVCILPNEYSTGIMYPITAERTRMLRMKDKNKFYFPPSQP-SKDLEG
TICLESDWESARKYLFTDLDGRTLGLPPPVSVFPKREPEWTGSFFN--TGIFREEQKCTF
RAMIQGFFCKQTDHVVLILHNVDV----PKSYPLVSITNGFVDTFSRVKDSTLCSTPTSV
SSFYSILPTRQITKICFVEQTPPLLHIFLLGNRA-SKLILAVFYNEIQSPHVFLEKRFIP
PTPVESASSLLDESAGANYFDIMNNLLYVVLQGEEPVEIHSSASIHLAFTVTFSVLEKGW
ERTMLERLTHFLQIDPNQIKFTLEMPGNKETLEAIANSRGKRKRHCPTVTCGGA-ASRFG
QRRPLMAEMTS-YRITPTTSVETLSKVIVIEVGDLPNTGSTEFIPTFLSNRLQNLAHQVI
TAQQTGVLENILGMTVRALLV-TQSEGVTG---YRNASSLGTGNLIYTRPSVLSVLVQPS
DGEVGIDLPVQPQLVFLDEKNQRVESLGLPSEPWVISASLEGASDSMLK--GCT-QAETW
DGYVSFSRLAVLISGSDWRFVFTVISPP-GTNFTARSKTFAVLPVAHKERSTIILALSLC
SVVSWLALSCLVCCWFKKSKN--RKIKPEDMSESQTKDQ-K----N-THISSKH------
QGLRVK-SAKEDTLMGEDMRMKVMQG-SQ-NQFPQQ-STDGVSKRNVSRRAVPE------
----DGAATPARRIPRITSQGL-TCVPGALAQQLTLQEPGNWKEAQKQLLRYQLAG--HN
QLLL-LCPDLRQERQQGQ-ESSQWNKGSDCMGLSPEK-GTCVPSETVCLHTAPSETIQ--
--------------------------

-------MTAWLISLMSIEVLLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---LGVF
YPNNGSQLEIHLVNVNMVVPALRSVPCDVFPVF--LDLPVVTCRTRSVL--SEAHEGLYF
LEAYFGGRLVSSPNPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLINRQMGSCYPTQEDHGLGTLQCRV
EGDY-IGSQNVSFSVFNKGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKDVRLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSQEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKVEPLWSNILLRLGFE
RGP-EISNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWSL----TRTSPESWQFHCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLLPLA---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLVTTQRRQRTS
PPLGGHFRIQLPN-TVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDLYTCY
EHVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATAN
QHTQVVVRVNDVPAHCPGSCSFRYLQGSTPCVHSVWYSVDGDI---NLMIYITGTGFSGD
SQFLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDM-VEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPR
GKDG-RIVNVTVIRGDYSAVLPRAFT YVSSLN PVIVTLSRNISNIA--GGETLVIGVAR-
-LMNYTDLDVEVHVQDALAPLHTQSAWGLEVALPPLPAGLHRISISINGVSIRSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSVILLGNLNCDVETQSF------------QGNVSLSGCSIPL
HSLEAGIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGL-LLN
SRRRSVRVDLS--GPFTCVILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGLTSE CQGNCTLFIREEASP VMDALSTNTSGSLTTVLIRGQRLATTADEPMVFVDDQL
PCNVTFFNAS-HVVCQTRDLAPGPHYLSVFYTRNGYACSG NVSRHFYIMPQVFH YFPKNF
SLHGGSLLTIEGTGLRGQNTTSVYIDQQACLTVNI-GAELIRCIVPTGNGSVALEIEVDG
LWYYVGVIGYNNA FTPELISISQSDD-ILTFAVAQISGAANIDIFVGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKREEDSCEAARHTY
VQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSIL-NLLHIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHALDTVLALEDAVDWHPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEASAPEGNLQHCLY
SMSEKMLGSRDIGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRNSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKD--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAGY
GYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWESA
GGAQI-FRSSNLRLKNF KVYSCRDFGIDVLESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMS
IGLANTPEVSYDLTMTDSRNKTTTVNYVCDTLSNPHGWMALLLDQETYSLQSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGQVQVILRVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVQLYSAYP
KNSWTHLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIY
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSAGSWIISSTLHQSCGGGIHAAANHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGHKCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSVIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENSGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
QFLMQGFICKQTDQVVLILDSTDAIWAIQKLYPVVSVTSGFVDVFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVG
QRRPLMMEMNS-HRASPPMTVETISKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENVLNMTIGALLV-TQSKGVIG---YGNTSSFKTGNLIYIRPYALSILVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSKPFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNQNN----H-IHISSKR------
RESQ-G-PKKEDAVVGEDMRMKVMLG-KV-NQCPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHGH-ICAPGAPAQQVYLQETGNWKEGQEQLLRYQLTG--QD
QLLL-LCPDFRQERQQLP-GQSRLSKQSGSLGLSQEKKASCGATEAFCLHSVHPETIQEQ
L-------------------------

-------MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDGLE---LGVL
YPNNGSQLEIHLVNVNMVVPALRSVPCDVFPVF--LDLPVVTCRTRSVL--SEAHEGLYF
LEAYFGGQLVSSPNPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTNITITGDFFDNSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKDVRLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSQEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWSNILLRLGFE
RGP-EVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMIVSFTIGFQNMV-KNTTCDWSL----TRTSPESWQFDCTDLWETCVRCFGDLQPP
PANSPVLVHQINLLPLA---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLVTTQRRQRTS
PPLGGHFRIQLPN-TVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDLYTCY
EHVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATAN
QHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDI---NLMIYITGTGFSGD
SQFLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVR PSGLAISATG-EDLFLNV
K PRLDM-VEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPR
GKDG-RIVNVTVIRGDYSAVLPRAFT YVSSLN PVIVTLSRNISNIA--GGETLVIGVAR-
-LMNYTDLDVEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSVILLGNLNCDVETQSF------------QGNVSLSGCSIPL
HSLEAGIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGL-LLN
SRRRSVRVDLS--GPFTCVILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGLTSE CQGNCTLFIREEASP VMDALSTNTSGSLTTVLIRGQRLATTADEPMVFVDDQL
PCNVTFFNAS-HVVCQTRDLAPGPHYLSVFYTRNGYACSG NVSRHFYIMPQVFH YFPKNF
SLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNI-GAELIRCIVPTGNGSVALEIEVD G
LWYHIGVIGYNKAFTPELISISQSDD-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKREEDSCEAARHTY
VQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKLER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSIL-NLLHIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTC L
RATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRNSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYI-----SWEAI
HGRKD--DWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAGY
GYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWESA
GGAQI-FRSSNLRLKNF KVYSCRDFGIDVLESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMS
IGLANTPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGQVQVILRVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYP
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIY
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVS AGSWIISSTLHQSCGGGIHAAASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGHKCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENSGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
QFLMQGFICKQTDQVVLILDSADAIWAIQKLYPVVSVTSGFVDVFSSVNANIPCSTSGSV
STFYSILPIRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCTSH-YRRVG
QRRPLMMEMNS-HRASPPMTVETISKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHRVI
TAQQTGVLENVLNMTIGALLV-TQSKGVIG---YGNTSSFKTGNLIYIRPYALSILVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSKPFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNQNI----H-IHISSKR------
RESQ-G-PKKEDTVVGEDMRMKVMLG-KV-NQCPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHGH-ICAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QN
QLLL-LCPDFRQERQQLP-GQSRLSKQSGSLGLSQEKKASCGATEAFCLHSVHPETIQEQ
L-------------------------

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
----------------------MVHKN-AWMISAKQD----LFLYQTYSEIQSVFPETGS
LGGRTDITITGDFFGSPAQVTIADIPCDIRHV--SPRKIECTTRSPGKGARLTAPQAGNR
GLLFEVGDAAEGLDLTEATPGYRWQIVPSASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQAFLHFSWSEDPRTKV-EVASIRVGTADWFDSWEQNG---NEGTWHRKTPKL
ELLGRVRYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVSTYLREKHQIRAHAQRLPEIQ
MLNVSG-RGNFFLTWGNVSSQPIPANATAHQIQTAIEELLAVKCKLEPLSANILLRLGFE
QGP-QGSSSDGDHTSATEPFCGRFSLHQPRHLVLTPRAGQKGYQLDQYAHLCFAYKGFMN
GILKMILTFTSDLQSIV-KNITCDWSP----VETRPESWRFTCTNLWETCVHPSGYLQPL
PANSSVLLHRIDLLPLA---QDMGLFYVDEIIITDTNVTVSQADSGTARPGGNLVESLSV
VGSFPVYNVTFWSAGCGVELPLISARSLQAEGTEE---------GSKLVQETTQRLQRTS
PPLGGHFRIQLSN-TVIPDVPVHISPGHLRKLLQSSADDFTSMYLNVSDLTVKEDLSSCY
EHVWTLSWSTQIGDLPIFIK---VSDENLTGVSPAVTTRVLYDGGVFLGPIFGDMLVTAN
QRTQVAVRVNDIPAYCSGSCSFQYLRGSTPQVHSAWYSHDNDI---NLLVHIIGTGFSGD
SQALQVTVNKTSCEVIFSNLTYVVCQMGVLSVGVHRVSMLVRPSGLAVNASG-EGLFLRV
EPRLDA-VEPSKAAEIGGLWATIRGSGLEGVSLVLFGSQSCAIDVNVSNSQRIQCKVPPR
GKDG-SIVNVTVIREDHSAVLPAAFTYVSSLNPVIVSLSRNRSNLADTGGDTLFIGMTL-
-LQNYTELDVEVHIQDTWARLHAQTAQGLEVVLPPMAAGLHRISVSINGLSIHSQGVDLH
IQYLTEVFDIEPCCGSLLGGTILNISGIGFSQDPALLWVAVGNRSCDIMNLTEENIWCET
SPASLLPG-MDMLA--IPARVQVWVGNVSFPHR--------EYT FLYEGTATPVVTALRA
ETTSSSLWFFVEGNSISNSVILLGSLHCDLEARSF------------RSNMSQSGCSFPL
HSLEAGVYPLQVRQKQMGFANMSVVPQRFVLA PQIIAIFPTQGSTCGGTVLTVRGL-MLS
SRRRSVQVGLS--GPFTCAILSLSDQTILCQVNLVGDPLPE-----AFFAM----NVTVL
VNGLTSECQGNCSLFIQEETTPAVDALTTNVSGSLTTVLIKGQRFGTTVNELVVFVDDYT
PCSVTFFNAS-HVACQVSDLNPGLHYLSVVHKRNGYACLRNVSRHFYIFPQVFHYFPKTF
GLHGGGLLTMEGAALKGQNATSVHVGQQACLSVNI-SAKLIQCIVPAGNGSFALEIEVDG
HLYHMGVIGYSKAFTPELLSISQTDD-VLTFAVDRITGAVHVKIFIGMSPCVGVSG----
NHTVLQCIVSSLPAGEYPIRGYDRMRGWASSVLVFTSGVTVTAVTENFGSCLGGRLVHVF
GAGFSPGNISAAVCGAPCQVLDNATVSAFSCLVLPLDVSLAFLCDLKSEEEGCEASSHTY
VQCDLTVTMGTERLPKSWPYLYICEECSQCLFEPDHRTE---SNFPS-FSGLFISPKVER
DEVLIYNSSCNIAMETEAEMECETPNQPITAKITEIWKSRGQNTQ---------------
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----------------------VVHKD-AWLISAKQE----LFLFQTYSEILSVFPTTGS
LGGGTDITITGDFFDSSAQVTVAGIPCEIKYI--SPRKIECTTRPLKQSTKLASPQPGNR
GLLFEAGNVQEGLDLTNSTPGYRWQIVPNASSPFGFWSEEGQHYRARLSGFFVAPETNNY
TFWIQADSPASLYFSQSEDPGTKV-KIAFIHDGIADWFDSWEMNG---HLETWQQKSPKL
ELLGGTKYYLEAEHYGITPSRGMSIGVQIHNTWLNPDVINTYHREKLQIRASAQRLPEIQ
MLKVTG-TGKFCLTWDGVSSLPVTVNATAAQIQRVIEELLTIKCKLEPLSAQILLRFGFE
QGQ-QDSGPDGDLSSGTEPFCGRFSIHQPQQIVRISETMRMRYQLGQYTHLCFAYKGHLN
DTMIISVSFKNKFHKIVKKKIACRWNT----EQLRTESWKFVCKDLWETCVHHSEDLHDR
LNNSPVVVHQIDVFPQV---HEKSQFYIDEIIVADRNLTVSQVNSRTARPGGKLIETVSV
TGIPPTYNITLWLAGCGSELPLIQPCYLAPEEANE---------DPRRISVTVQRLQSIS
PPLRGHFQIQLPK-TVIPGIPIHISAHDLRELLQGSNDDFAAQFFTVSDFKVQKDLNTCY
EHVWTLTWMSQTGDLPNIIS---VSAENLTGVNPTVNTQVVYDGGVFLGPIFGDMLVTPN
IYPQVTVRVNDIPAHCLGSCSFQYHQEATPLLQAAWYSYGDNS---NLLVYIMGSGFPGD
SEALKIEVNQQICEVMFSNQTYVTCQIDFLPIGNYEVVMLI KHIGFALNVSGGEGIYFNI
EPKL KV-VKPSVASEIGGFWATIEGTSLEEVNLVLFGSQPCPINISSRSMERIQCKVPPW
GNGSGMLMNVTIITRNLTLTYLEAFK YTPSLN PVIMSLSRNRSNTA--GDQTLFIGTTS-
-LENYTDLDVKVHIQDTLAQVLKQEPQGLEVTLPPLPTGWHSISVTMNGVNISSEGVD LQ
IQYITKVLWTE PCCGSLLGGTTLTISGIGFSKDSSLVSVSVGNQTCSIVNSTEETIWCET
LSAPRL PG-TEPQ--AVVLPIEVSIGNICAPHDPSFDLGKKDFTFIYHTALTPYVTAMQG
QIRGDILELHVEGNNISKSIVLLGDMKCDLELQSF------------SFNRTQYFCSLPL
ANVEAGIYPIQVFQKDMGFANISAIPYSFTVS PQVADIFPTHGSVCGGTMLTITGL-AFK
SRMNLVRVDLS--GPHTCTIWNWDDQMILCQVSLVG-YLPK-----ASFAL----NVTIT
ANGISSECQGNCTFYLQEEATPIIDTMTTSVSGTLTTMWIGGQKLATATDELVVLIDDCL
SCDITYYNAT-QVECQLSDLGPGLHHFSLLNKRSGFACLPTLPSHFSVAPRVLGYHPQNF
GVNGGGLLTIEGTMLRGQNTTLVLVGHQACLTVNIISSVLIQCIVPPGNGTVVLEIEVDG
NLYEVGMIGYSDIFTPKLLSILQIDGLIVTFMVDRTTGAKNMRIFIGTSPCVGILG----
NHTVLQCTVSQLPAGKYQVKGHDHLRGWASSTLVFTSKVIITSIYSNFG-CLEGRLLHVH
GSGFSPGNISATICGVPCEILDNATVTSFSCLVLPLDDSLAFLCNLRPLEENCDATKATY
IQCELIITIGTNSLLRSWCYIYMCEESPWCTLTLDHQVA---SSLRL-FSGFFMSPKVER
DEVLIYNSSCNITMETEAEMECEAPNQPITAKITEIRKNWGQNTQ---------------
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-------------------------SCRSCHIIPEEGSIAGGTWITIVFDXXX---XXXX
XXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQVQGWIITGRTET
FDNDVDYVDXXXXXXX---------XXXXXXXXXXXXXXXXXXXYPIEEDLGFGVLQCRV
EGHY-IGSQNVSFSIFNKGX-XXXXXX-XXXXXXXXX----XXXXXXXXXILSVFPTTGS
LGGGTDITITGNFFDCPAQVTVAXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXNR
GLLFEAGDVQEGTDLSNTSPGYRWQIVPNASSPFGFWSXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXV-KIAFIQTGIADWFDSWEMNW---HLETWQQKSLKL
ELLGGAKYYLEAEHYGITPSRGMSIGVQIHNTWLNPDVVNTYHREKLQIRASAQRLPEIQ
ILHVTG-TGKFCLTWDGVSTQPVTVNATAAQIQTAIEEMLMVKCKLEPLSAQILLHFGFE
QXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLCFAYKGHMN
DTMTISVSFTSKFHKIVKKRIACGWNP----EQLKTEXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXSQINSRTARPGGKLIESLSV
TGVPPTYNITLWLAGCGSEVPLIQPCYLPREEADE---------DLRGVNVTIQRLQRIS
PPLGGHFQIQLPK-TVIPGIPVHISAPDLRELLRGSNDDFAAQFFDVSDFKVQKDLNTCY
EHIWTLTWMSQTGDLPNIIS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXVTVRVSDIPAHCLGSCSFQYHQESTPLVQAVWYSYDDDV---NLLVCIMGSGFPGD
SKALKIEVNQQICKVMFSNQTYVTCQMGFLPTGEYQVVMLVRHFGLALNVSGGEGIYFNI
DPKLKV-VEPSVAPEIGGFWATIQGTSLEEVSLVLFGSEPCPINISSRNMERIQCKVPPL
GIGG-KFVNVTIITRNLSLTYPEAFK YTPSLN PVILSLSRYRSSTA--GDQTLFIGTTS-
-LLNYTDLDVKVHIQDTLAQILKQGPQGLEVVLPPLPTGWHSISVTMNGVNISSDGVDLQ
IQYI TKVFQIEPCCGSFMGGTTLTISGIGFSKDPSLVSVSAGNQTCSIVNSTEETIWCEM
SSAPQLPD-TEPQ--AVTVPIEISIGNIYVSHDPSFD LGKKDFTFTYHTALTPFVTATQG
QIRGDIMELQVEGNNISKSIVLLGDKKCDLELQSF------------SFNRTQYFCSLLL
ANMEAGIYPIQVFRKDVGFANMSAVPHSFTVP PQITDIIPTHGSVCGGTLLTIVGL-AFK
SRMSLAQVDLS--GTHTCAIWNWDDHIVLCQVNLVE-PLPK-----SSLAL----NVTIT
ANGISSECQGNCTFYLEEEVTPIMDTLTTSVSGTLTTILIGGQKLATDTDELVVLVDDRL
SCDITFYNST-QVECQLSGLGPGLHQLSLLNKRSGFACLRTVPPYFIVTPQVFGYHPQNF
SVNGGGLLTIEGTTLRGNNTTSVLVGHQPCLTVNI-SPVFIQCIVPPNNGTVILKIEVDG
NLYDVGMIGYSDAFTPVLLFILQTDGLIVTIMVDRTTGAKNMKIFIGASLCVGILG----
NHTILQCSVPPLPAGQYQVKGHDHLRGWASSTLVFTSEVTITSIYSNFG-CLDGRLLHVH
GGGFSPGNISAAVCGVPCQILDNATVTYFSCLVLPLNXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX-XXXXXXXPKVER
DEVLIYNSSCNITMETEAEMECEAPNQPITAKITEIRKNWGQNTQGSFPLQVCRRWSRAH
SWIPQGLPQDGDNVTVESGQTMLLDITTSVL-SMLHIKGGKLMFTGPGPIELHAHCILVS
HGGELQIGSQEEPYHGKALIRLHGNSPSTTFFPYGAQFLAVRNGTLSLHGLMPEVSFTHL
QTTAQANDTMLILEDPVDWHPGEEV-IISGVTLEGSRGQEEVAIIDRVHGADLYLKSPLX
XXHGFLEHNIAGRHLALRATVALLSRNV-IQGNLTSDRMAHLGLCTEIKIPEDVFQHCLY
FMSKKNLGSVTLGAVVIVQSFPGEPSQVQLQGVQFQYMGQAFRKHLCALNMIGS--MKDS
YIRGCSIQDSF-SRGLSLSRTSNLIVENNVFYNILGHGLLLGTYMEMRHL-----PWKAV
PRRKT--DFLAQGNIIRNNVIIGIFGTEGLXXXXXXXXXXXXXXXXXXXXXRNMVCAAGY
GYFFHLATGETSKAPLLSFTQNVVHSCTRYGLLVYPRFEPPRVNDTGPTLFQNFTVWGSQ
GGIQI-FRSSNLQLKNFQIYPCKDFGIDILESDANSSIIDSLLVGHYAAK---ESSCMSA
GIKTPKRQELLVSKTTFVNFDQNNCIAIRTCSSCYRGQGGFTVKTEQL--KFLNSPNRVA
FPFPHAAIIEDLDGSISGSNGSYLLASAENLASSCXXXXXXXXXXXXXXXXXXXXXXXXX
XXXIEAPDVTFDLTVTDSRNQTTTVNYVYDTLSNLYGWMALLLDQDTYLLRFE-APWIN-
LQXXXXXXXXXXXXXXXXXXXXXX-XXXXX---XXXX--XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXSGEGQVQLTLLVKEGV-NPTAPVPSAVPESILKWSHPTTWQDVEEG
WGG--YNHTTPTAGDDVVILPNRTILVDTELPFLKGLYILGTLEFPVNRSNILNVACIIV
AGGELKV--GTFSEPLQKGQTLLIQLQASEGVHCDRLDGIRIAPGTIGVYGKVQLHSAYP
RKAWTHLRADIASGNDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXSSHSMEDGRHISLAAEVGLLTRNIKIQPDVPCGGRMVVGSFQKPNGEEFSG
TLQLSN---VEIQKFGSLLNPSIEFNNVSLGSCIISSTVHQSCGGGIRVHSSKSIFLYDN
ILFDIIGHGIDLEGQNHSLIKNLIVLTKQPQREMYWVTGIKVNQANDVLLNGNAVAGSER
IGFHVRGHSCSMAENPWVGNVVHSSLHGLHLYKGDGLYNCSGISGFLSYKNFDYGAMFQV
ENSLEIDNVTLVDNVVGLLPLVYTSSAEQCSLKKKQIVLRNSIIVATSSSFDCIEDRIKP
LSADFTSRHRAPSNPRGGRVGILWPGFTVEPNQWPQDAWHKV-RNYPSVSGIMKLD-GVT
FSDFVKSCYSNDLDVCILPNPDSTGIMPPITAQRTKMTKVKDQNKFYFPLLXX-XXXXXX
XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX--XXIFKEDQKCTY
RPSMQSCVCTQMDYVLLILDNIIIAPGRTNPSPVISVTSGFVGTFNSVAAHPSCFASLSL
LAFYSILPTNSLTKICFMNWVPQAMRFYLIGSERSSKL-LAVFYPELQSPRVFFRGHFIP
PTSVPADSWQESGAIGTNHFSFTDNLLYILLQGDEPVEVHSAVSIHVAFTVTLSITLEGW
EQTIQQGLAHFLQIGQDCIRIVHVMPGGERTLKAIADGAAKRKHHCPTGTLCTS-CHRMG
QHRRLMKKMET--WVPPPTYSETNSKVVVTEIGDLSVMGNANMAPSLSTDALQRLAHRII
TAQQTGELQEALDMPIEALLI-SQSAGVDT---SGXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXGWVVESLGPPSEPWIVAVSLEGASETVLK--GHT-HSEAH
QGQVSFSNLAVSSSGSKWYFLFTVISPP-GAKFMVRSEPFAVFPVNIGEKSTILMALVLC
SAASWVAVCFLVFCWFKKRKV--K------------------------------------
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------MMLAWLVSLLSMEVLLLAKPYSSFQFEPAEGSLAGGTWITVVFDGLD---RSIL
YPNNGSQLQIDLVSV--AIPTL-RIPCDVSPAF--VDLPVVTCQTRSLP--SEADAGPYS
LEMRSGEQVLGTPCPGSLDSCTFKFSKDQTPVLYQVYPASGVPGEVVSVYGRVITTWLET
FDPDVDYIESPLILEA---------REDKWLTPCSLINRQTGSCFPIQEEHGLGNVQCRV
EGDY-IGSQNVSFSVFNKGR-SMVHKE-AWLISAKQE----LFLYQTYPEILSVFPKVGS
LGGRTDIIITGDFFDPSARVTIAGIPCDIRYV--SPRKIECTTRAPGNEARLTAPQAGNR
GLRFEVGDATKDVELTEATPGYRWQIVPNASSPSGFWSKEGRPFRARLSGFFVAPQTNNY
TFWIQADSQASLCFSSSEEPRTKV-EVASVGVGTADWFDSWEQIG---NEGSWHQKTTKL
ELQGGAKYYLEAEQHGIAPSRGMRIGVQIHNTWLNPDVVNTYLLEKHQIRARAQRLPEIQ
VLHVSG-KGNFFLTWGNVSSQPVPANATAQQIQTTIEELLVVKCNLAPFSAHVLLRLGFE
QGL-EGSRSDGVRTSSTEPFCGRFSLGQLGHLILIPEAADKGYQLDRYPYLCLAYRGHMN
KTLDMTVSFLFGFQTIM-KNITCDWSL----TDPHPESWQFTCINLWDTCLCHSEDIQSS
LANTPLLAHRIDIRPVV---PEAGLLYVDEIILADTNVTVSQADSGRACPGGNVVESVSV
VGVPPVYSISSWLAGCGSELPLITACSVSTEGTGD---------GSELIEVTAQRLQRTS
PPLGGHFFLYLSD-TVIPDVPVRMSARQLHKLLQDSADESTSGYLNAGDFTVTEDLNSCY
EHVWTLSWTTQTGDLPNFIR---VSDQNLTGVNPTVTARVVYDGGVFLGPIFGDMLATAN
QQTQVAVQVNDIPAYCSGSCSFQYQQESTPSVDHVWYSLGSDV---NLLVHFTGTGFPRD
TQFLQVTVNKTSCEVLFSNETNVACELALLPVGVHQIFML VIPSGLAVHASG-EDLLLHV
E PRLDA-VEPSTAAEIGGRWVTLRGSSLEGVSLVLFGTQSCVIDAIRSNSQQIQCKVPPR
GKDG-YTVNVTVISGDHSTVLARAFTYVSSLNPVIVSLSRNRSSIA--GGEILFLGMSL-
-LVNYTDLDVQIHVQDTSAQVLSQTAWGLEVVLPPLVPGIHVISAFINGVSIRSQGVDLY
IQYLTEVFSVEPCSGSLLGGTLLSLLGTGLGRDPALIRVLVDNHPCDIVNLTEVNIWCET
PPAVLPPR-ADVL T--VLASVEIWAGNTSFFHGP--SLVGKGFTFTYEAAATPVVTAMWG
EFRNNSVRFYVEGSNISDSVILLGSLKCELEVQFF------------GDSMNLSGCFFPL
HSLEAGVYTLQVRHKRMGFANMSVVPQKFELS PQIIAIFPTHGSKCGGTVLTVKGM-AFS
SRKRSVHVDIS--GPFACMILSLEDHTVLCQTRFVGDQFSE-----ASLAL----NITVL
VNGLTSKCKGNCTLFIEEAATPIVDALTISISGSLTMVLMRGRRLATTADEPIAFVDDQL
PCHTTFFNTS-HVACQIRDLAPGFHYLSAVHTSAGYACLNSVSRNFFIVPQVLDYFPKDF
SIHGGSLLTIKGTALRGWKATVVYVGRQACLTVNF-SSDFIQCIVPAGNGSAALEIDV NG
VLYHIGLVDYSSIFTPELLSVSRSQD-ILTFTVARISGAANVDIFIGTSPCLGVAG----
NRTVLQCMVPLLPAGEYLVTGYDHSRGWASSTLILVLRATVTSVTKNY-GCLGGRLLHVL
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLHVSLAFLCDLRHAEDSCKVRSSTY
LRCDLTVSMGTERLPGSWPYVYLCEESSLCLFEPDHWTE---SVFPS-FSGLFLSPKVER
DEVLIYNSSCNITMETEAEMECEMPNQPITAKITEIQKSWGQNTQGNFSFQFCRRWSRPH
S WFPQRVPHDGDSVTVETGHLLLLDANTSFL-NSLHIKGGKLIFMDPGPIELRAHSILIT
DGGELHIGSEEKPFQGKARIKIYGSVHSTPFFPYGVKFLAVRNGTLSLHGSVPEVTVTY L
QAAAHAGDKVLTLGEAVDWKPGDEAVITSGMTVAGAEATE-VVVVETVHNADLHLRNPLR
YSYDFRENWVAGENPILKPTVALLSRNIIIQGNFTLERVKLLNSCQEANTAKGNLKHCLY
SKSEKMLGARDLGARVIIQSFPEEPSFVKLKGVQFRDLGQAFHKHLSSLALVGA--MRGS
YIQSCSVWNSF-SR GLSMHRTWGLKVDSNVFYKIVGHALLLGSYLDGRFS-----TSETV
TGRKN--GWWEQGSTIRNNVIISVSAAEGLSGSEMLAPAGIYTFSPTNVMEGNRVCAAGY
GYVFHLVTSQTLQAPLLSFNWNTAHSCTRYGLLVYPKFQPPWNNDTGFTLFQNFMVWGSA
GGAQI-FRSNNLHLKNF QVYACRDFGIDILESDANTLITDSFLLGHFTHK---GSLCMSA
GIKTPQRWELTISNTTFVNFD-GNCVAIRTCSGCFQGQGGYTVKTRQL--KFVNSSNLVA
FPFPHAAVLEDLDGSLSGKNGSHVLASMETLSDTCLTNASFSQIVPGSVCGEAVLFHRMS
IALANSLDVPKNLTITDISNKTITVNYVEDTLSNYYGWMALLLDQETYSLQFE-SPWMN-
RSLQYSATFDSFAPGNYLLIMHRD-LPPYP---DILLRCGSQVGHSLPFHPLPSQDRACD
WFFNRQLRQLTYLVSGEGQVKVFLQLKPGV-PPSVSASTSVPESASRWSLPETWQDVEKG
WGG--YNHTIPGPGDDVLILPNKTVLVDTDLPVLRCLYVMGTLEFPVDRSNVLSVACLLI
AGGELKV--GTLENPLEKDQRLLIFLRASEEVVCDYFEGIHVDPGTIGVYGKLRLHSAYP
KKSWVH LGADIAPGNERIIVHNAVDWQPHDTIVLSSSSYEAHEAEVLTVKEVKGHHIRIY
ERLKHRHIGSTHTMEDGQQVHLAAEVGLLTRNIRIQPDSSCRGRLLVGSFRKSSGEDFSG
VLQLLN---VEIQNMGLPLYSSIEFTGVSAG SWVISSTVHQSCSVGIHASSSHGVILTDN
VVFGTNGHGIDVEGQNYSLTNNLVILTMQSANSSPWVAGIKVNYAEDIILHGNVVAGSER
LGFHVGGHGCSS-EVLWSDNVVHSSLHGLHLYKKHESNNCTGVSGFMAFKNFDYGAMVQT
ENSVDIQNITLVDNTVGLLAITYVSSALLSSVSTVQITLRNSVIVATSSSFDCIHDRKAP
QSANWTSTDRAPSNPRGGRIGILWPVSASEPNAWPQEPWHKV-RSRHSVPGIMKLQ-DVT
FSSFVKSCYSNDLDVCILPNEYSTGVMYPITAERTRMLGIKDKNKFYFPVLQS-SKDLVG
TICPTLVCEYPRKYLFTDLDGRTLGLPPPVSVFPRTEEEWTGSFLN--TGIFREEQKCTF
RAMNQGFFCKQTEHAVLILDNVDATWTIPKSHPLVSVTNGFVDTFSIVKDSDLCPPTSSL
STFYSILPTRQMTKVCFPEQTPPFLRFLLLGNQRASKLILAVFYNEIQSPHVFLDKSFIP
PTPLESAFSLLAEPSGANYFDIMNNLLYVVLQGEEPVEIHSSVSIHLALTVTFSVLEKGW
ERAMLESLSDFFQIDPNQIRLTLEMPGNKETLEAIANSERKRKRNCPSVTCGGP-SIRYG
QRRPLMAEMTS-LKITPATTLETFSKVIVIEVGDLPNIRNSEPIQSLPSNRLQRLVNQVI
TAQQTGALENVLGMTVGALLV-TQSKGVTG---YRNASSLITGNLIYTRPSELSILVQPS
DGEVGIELPVQPRLVFLDEKNERVESLGLPSEPWIISVSLEGASESVLK--GCT-LAETR
DGYVTFSRLAVLISGSNWHLFFTVISPP-GTNFTARSRTFVVLPVASKERSTIILALSLC
SVASWVALSCLVCCWFKKSKT--RKIKPEDISESQAKEQKK----N-THNSSKP------
RGLQAK-TAKENTLMGEDMRMKVMQG-MQ-SQFPQH-SMDGVSKRKVSRLAVTE------
----ERTTTPAPKIPRI------TCVPGSLAQQLTLQEPGNWQEAQQQLLRYQLAG--RN
QLLL-LRPDLRQERKQGQ-EPSQLDKGSDCTGLSQEK-ATCIPTETFSLHTAPPETIQ--
--------------------------

-------MTAWLISLMSIEVLLSAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGVL
YPNNGSQLEIHLVNTNMMAPALPSIPCDVFPVF--LDLPVVMCQTRSLL--SEAHEGLYS
LEAYFGGQLVSSPSPGPRDSCTFKFSKVQTPIVHQVYPPSGVPGKLIHIYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLINRQTGSWYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMIHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKDARLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNATSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNT---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
RGL-EVSNSDGDLTSGTEPFCGRFSLRQPRHLVVTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQTMV-KNTTCDWSL----TRTSPKSWQFHCTDLWETCVCCSGDLQPP
PTNSPVLVHQIDLVPLA---QGTGLFYVDEIIIADTNITVSQADSGAARPGENLVESVSV
VGSPPVYSVTSWLAGCGTELPLITAHSVPTEGTEE---------GSGLVLATTQRRQRTS
PPLGGHFRIQLPN-TVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFSVKEDLYTCY
EHVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKTNCKVIFSNQTNIVCQTDLLPVGVHRILMLVR PSGLAINATG-EDLFLNV
E PRLDT-VEPSRAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRILCKVPPR
GKDG-HIVNVTVIRGNHSAVLPRAFTYVSSLNPVIVTLSRNTSNIA--GGETLVIGVAR-
-MVNYMDLDVEVHIQDALALVHTQSAWGLEVALPALPAGLHRISVSINGISIHSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALLWVLVGNRSCDLVNLTEASIWCET
LPAPQIPG-AGAPT--VPAAVEVWAGNRSFAHGPSPSLVGDGFTFMYEAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSVPL
HSLEAGIYPLQVRQKQMGFANMSAVPQQFAVTPRIMAIFPSQGSACGGTILTVRGL-LLN
SRTRSVRVDLS--GPFTCVILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGITSECH GNCTLFIREETSPVMDT LSTNTSGSLTTVLIRGQRLGTTADEPMVFVDDQL
LCNVTFFNTS-HVVCQARDLAPGPHYLSVFYTRSGYACSGN VSRHFYIMPQVFHC FPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIQCIVPTGNGSAALEIEVD G
LWYHIGVIGYSNAFTPELISVSQSDG-ILTFAVAQISEAANMDIFIGMSPCMGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKHEEDSCEAARHTY
VQCDLTVAVGTERMLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGKFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDTVLALEDAVDWHPGDEVIIISGTGVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPKGNLQHCLY
SISEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRSSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEIRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNVAHSCTRYGLFVYPK FQPPWDKVTGITLLQSFTVWESA
GGAQI-FRSSNLRLKNFQVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSPCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSRGQGGFTVKTSQL--KFVNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IDLANAPEVSYDLTMTDSRNKTTTVNYVRDTLSNPHGWMALLLDHETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILIRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVTGEGRVRVILRVKEGM-PPTISASTSAPESTLKWSLPETWQGVEEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYP
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSAGSWIISSTLHQSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHRCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSIFPKTEAEWTASFFN--TGTFRGEQKCTY
RFLMQGFICKQTDQVVLILDSTDATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSAPLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFIHEIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVG
QRRPLMMEMNS-YRSSSPMTVETISKVIVIEIGDLPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENILNMTIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYALSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSQSFAVLPVTTKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKR------
RKSQ-G-PKKEDAVVAEDMRMKVMLG-RL-NHCPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHGH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL--LPGLRQERQQLP-GQSWLSKQSGRLGLSQEKKASCGATEAFCLHSVHLEAIQEQ
L-------------------------

-------MTAWLISLMGVEALLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGVL
YPNNGSQLEIHLVNTNMVAPALPSIPCDVFPVF--LDLPVVMCRTRSLL--SEAHEGLYS
LEAYFGGQLVSSPSPGPRDSCTFKFSKEQTPIVHQVYPPSGVPGKLIQVYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSARVTVAGIPCDIRH--VSPRKIECTTRAPGKDARLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
GGL-EVSNSDGDLTSGTEPFCGRFSLRQPQHLVVTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWS----LTRTSPKSWQFRCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLVPLV---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLATTQRQQRTS
PPLGGHFRIQLPN-TVISEVPVQISAHHLHQLLQNNADEFTSRYLNASDFSVKEDLYTCY
ERVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKMNCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-HIVNVTVIRGNHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAR-
-LVNYTDLDVEVHIQDALALVHTQSAWGLEVALPALSAGLHRISVSINGISIHSQG VDLH
IQYLTEVF SIEPCCGSLLGGTILSISGIGFSRDPASVWVLVGNRSCDIVNLTEASIWCET
LPAPQIPD-A GAPT--VPAAVEVWAGNRSFAHGPSPSLVGNGFTFMYEAAATPVVTAMQG
EITNSSLSLRVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSIPL
HSLEAGIYPLQVRQKQMGFANMSAVPQQFAVT PRIMAIFPSQGSACGGTILTVRGL-LLN
SRTRSVRVDLS--GPFTCEILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGITSECH GNCTLFIREEASPVMDT LSTNTSGSLTTVLIRGERLGTTADEPMVFVDDQL
LCNVTFFNAS-HVVCQTRDLAPGPHYLSVFYTRNGYACSG NVSRHFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIRCIVPTGNGSAALEIEVD G
LWYHIGVIGYSNAFTPELISISQSDG-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCMVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKHEEDSCEAARHTY
VQCDLTVAVGTERMLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFVSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQSLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTH L
RATAHARDTVLALEDAVDWHPGDEVVIISGTGVEGAKPMEEIVTVETVQDTDVYLKSPLR
YSHNFTENWVAGEHHILKVTVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIIQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRSSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGITLFQSFTVWESA
GGAQI-FRSSNLRLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFINSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLASAPEVSYDLTMTDSRNKTTTVNYVRDTLSNLHGWMALLLDQETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILWVKEGM-PPTLSASTSAPESALKWSLPETWQGVEEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLIFLRASEGVFCDRLNGIHTDPGTIGVYGKVQLYSAYS
KNSWTH LGADIASGNERIIVEDAVDWHPHDKIILSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSEGSWIISSTLHQSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHKCS-CGLLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHI
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
LSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSIFPKTEAEWTTSFFN--AGTYREEQKCTY
RFLMQGFVCKQTDQVVLILDGADATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSSVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFLREIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVS
QRRPLMMEMNS-YRSSPPTTVETMSKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENILNMTIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYVLSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAESQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSQSFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKC------
RESQ-G-PKKEDTVVAEDMRMKVMLG-RL-NQCPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHGH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL--LPGLRQERQQLP-GQSWLSKQSGRLGLSQEKKASCGATEAFCLHSVHLEAIQEQ
L-------------------------

-------MTAWLISLMSIEVLLLAVPHLTLHIEPEEGSLAGGTWITVIFDGLE---SSVL
YPNNGSQLEIYLVNVSMVVPALPSIPCDVFPVF--LDFPVVTCRTRSLQ--SEAHEGLYC
LEAYFGGQLISSPSPGLRDSCIFKFSKAQTPIVHQVYPSSGVPGKLIHVYGWIITGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGNCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNRGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDSSAQVTIAGIPCDIRHV--SSRKIECTTRAPGKNARLTSPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKM-KVASISVGTTNWFDSWEQNR---DEGTWQQKTPKL
ELLGGARYYLEAEHHGIAPSTGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRFPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLSANILLRLGFE
RGP-EVSSSDGDLTSGTEPFCGRFSLRQPRHLVLAPSAAQKGYRLDQYTQLCLAYKGHTN
KILKMTVSFTIGFQNMV-KNTTCDWSL----MRTSPKSWQFRCTDLWETCVRCSGDLQPA
PANSPVLVHQIDLLPLA---QETGLFYVDEIIIADTNLTVSQADSGTARPGGNLVESVSV
AGSPPVYSVTSWLAGCGTELPLITARSVLTEGTEQ---------GSGPVLVTTQRRQRTS
PPLGGHFRIQLPN-TVISDVPVHISAHHLQQLLQNNADDFTSRYLNASDFTVKEDVNTCY
EHVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAYCSGSCSFQYLQGSTPWVHSVWYSIDGDI---NLMVYITGTGFSGD
SQFLEVTVNKTNCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAIIATG-EDLFLNV
E PRLDA-VEPSRAAETGGLWATIRGSSLEGVSLVLFGSYSCAINVTISNSSRIQCKVPPR
GKDG-HIVNVTVIRGDYSAVLPGAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAL-
-LVNCTDLDVEVHIQDALAPVHTQAAWGLEVALPPLPAGLHGISVSINGVSIRSQGVD LH
IQYITEVF SIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLMEASIWCVT
PPAPQMPH-AGTST--VPAAVEIWAGNRSFTRGPSPSLVGNSFTFTYEAAATPLVTALQA
EITNSSLRLRVGGSNLSNSVILLGRLNCDVDTESF------------QSNASLSGCSIPL
HSLEADIYPLQIRHKQMGFANRSAVPQPFAVM PLIMAIVPSQGSVCGGTILTVRGL-LFN
SRRRSVRVDLS--GPFTCVILHLEDRTILCQVSLAGDPLLG-----ASFTM----NVTVL
VNGLTSECQGNCT FFMQEEASPVMNAL TTNTSGSLTTVLMRGQRLGTTADELMVFVDDQL
PCNVTFLNAS-HVACQMRDLAPGLHYLSVFYARNG YACTGNVSRHFYITPQVF HYFPKNF
SIHGGGLLTIEGTGLRGQNTTSVYIDQQACLMMNI-SAELIQCIVPTGNGSVALGIEVD G
LLYHIGVVGYSNAFTPELLSISQRDD-ILTFTVAQISGAANIDIFIGMSSCMGVSG----
NHSVLQCVVPSLPAGEYHVRAYDYIRGWASSVQVFTSRVIITAVTKNFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVPPLDVSLTFLCDVKHEEDSCEAARHTY
VQCDLTVAVGTEQLLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FLGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNSPFQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSIL-NLLHVKGGKLIFLAPGPIELRAHAILVS
DGGELRIGSKDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGLLPKVIVTH L
RATAHARDTVLALEDAVDWHPGDEVVIISGTSVEGARPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVACQEANAPEGHLQHCLY
SMSEKTLGSRDMGARVIVQSFPEEPSGVQLRGVQFRVLGQAFRKHLSSLILVGA--MRES
FVQGCTVWNSF-SRG LSMCRTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
RGRKD--DWSGHGNIIRNNIIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCAAGY
GYFFHLVTSQTSRAPLLSFTQNIAHSCTRCGLFVYPKFQPPWNNVTGTTLFQNFTVWESA
GGAQI-FRSSNLHLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTIFVNFDLINCVAIRTCSGCSRGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLANAPEVSCDLTMTDSRNKTTTVNYVRDTLSNPYGWMALLLDQETYSLHFE-NLWIN-
RSLQYSATFDNFAPGNYLWLVHTD-LPPYP---DILLKCGSRVGLSLPFLPSPAQNQGCD
WFFNSQLRQLTYLVSGEGQVQVILQVKEGM-PPTISASTSAPDSALKWSLPETWQGVEEG
WGG--HNNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVLGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGMHVEPGTIGVYGKVQLYSAYP
KNSWTHLGADIASGNERLILEDAVDWRPQDKIVLSSSSYEPHEAEVLTVKEVKGHYVRIH
ERLKHRHIGSVHVMEDGRHIHLAAEVGLLTRNIQIQPDVSCRGRLLVGSFRKSSREEFSG
ILQLLN---VEIQNFGSSLYSSVEFSNVSTGSWIISSTLHQSCGGGIHAAASHGVRLNDN
IVFSTAGHGIDLEGQAYSLTNNLVVLMTQPAWSNIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGYKCSSCEVLGSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENNVEIENITLVDNTIGLLAVVYVFSAPQNSIKNVQIVLKNSVIVATSSSFDCLQDKVKP
YSANLTSSDRAPSNPRGGRIGVLWPVFTSEPNQWPQEPWHKV-RNDRSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKMKDKNKFYFSPSQP-RKDLGK
VVCPELDCATPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
RFLMQGFICKQTDQVVLVLDSANATWANQKLYPVVSVTSGFVDIFSSVNANFPCSTSGSA
STFYSILPTQQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTLVQSTSLLLNESTGANYFSIMDNLLYVVLQGEEPIEIRSGVSIHLALIVMVSVLEKGW
EIVMLERLSNFLQIGHNQIRFIHEMPGQEETLKAIADSRAKRKRNCPTVTCASH-YRRVS
QRRPLMMEMNS-YRVSSPTTVETISKVIVIEIGDLPAVRSNGMISSLSSNKLQNLAHQVI
TAQQTGILENVLNMPIGALLV-TQSKGVIG---YGNTSSFKTGNLIYIRPYALSVLVQPS
NGEVGNELPVQPQLVFLDKQNRRVESLGPPSEPWTISASLEGASDSVLK--GRT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSKPFAILPVTRKEKSTIILAASLS
SVVSWLALSCLVCCWLKRSK--NRKIKPEEIPESQTSNQNN----H-IHISSKC------
QESQ-G-TKKEDTVVGE-------------------------------------------
--------------------------------PVYLQETGNWKEVQEQLLRYQLAG--QD
QLLL-LCPDLRQERQHLP-EQSLLSKKSGNMGLSQEKKASCGATEAFCLQSVHPGTIQEQ
L-------------------------

-------MTGWLVSLTSIKILLLAVPCLSVHIEPEEGSLAGGTWITVIFDGLE---PGLL
YPANGSQLEIHLVN--VAVPMLPIIPCDISPVL--LDLPVVMCRTRSLL--SEAHEGLYY
LEVQAGGQVVGSPSSGPRDSCTFKFSRAQTPIVYQVNPPSGVPGNLIHVYGWIITGRSET
FDFDAEYIHSPLMLEA---------QGDKWVTPCSLVNRQTGCRXXXXXXXXXXXXXXXX
XXXX-XXSQNVSFSVFNKGX-XXXXXX-XXXXXXXXX----XXXXXXXXXILSVFPETGS
LGGRTDITITGDFFDNPAQVTVAGILCDIRHV--SPRRIECTTRSPGKGARLSAPQAGNR
GLLFEVGDAAEGLDLTEATPGYRWQIVPNASSPFGFWSEEGQPFRARLSGFFVAPETNNY
TFWIQADNQASLYFSQSEDPRTKV-KVASITVGTADWFDSWEQNG---SEETWQQKAPKL
ELLGGARYYLEAEHQGRAPSRGVRIGVQIHNTWLNPEVVSTYLREKHQIQARAQRLPEIQ
MLMVSG-TGNFSLTWDNVSSQPIPANATAHQIQTALEELLAVKCKLEPLSANILLRLGFE
QGL-EGFSSDGHLTSGTEPFCGRFSFHQPRHLVLIPAAAQKGNRLDQYTHLCLAYKGHMN
TILTVTVSFTIGFQNTVKNNVTCDWSL----AGASPNSWQFACTDLWKTCVHRSVQLQPP
PTNSPVLVHQIDLLPLS---PEMDVFYVDEIIIADTNLTVSQADSGTARPGGNLLELLSV
VGSPPVYSVTSWLAGCGLELPLITASSVPTEGAEE---------GSGLVQVTTQRLQRAS
PPLGGHFRIQLSH-TVIPAVPVHISASHLQKLLQTNADDFTSRYLNVSDFTVTEDLKSCY
EHVWTLSWSNQVGDLPSFIR---VSDENLTGVSPAVTTRVVYDGGVFLGPIFGDMLVTAN
QYTQVVVRVNDIPAYCSGSCSFQYLEGSTPRVHSVWYAL-DDI---DLLVYITGSGFSGD
SEALQVTVNKTSCKVIFSNQTNVVCQTGLLPVGVHQISVLVRPSGLAINASG-GGLFLNV
EPRLDA-VEPSRAADIGGLWATIRGSSLEDVSLVLFGSQFCAINVTTSNSRRIQCKVPPK
GEDG-PTVNVTVIRGDHSVVLPKAFT YVSSLN PVIVSLSRNRSSIA---GETLSIGMVL-
-PMNHTDLDAQVHIGDTRARVRAQAAQGLEVVLPPLPAGLHGISVSINGAHIHAQGVDLH
IQYI TEVFSIQPCCGSVLGGTILSISGRGFSSDPALVWVLVGNRSCDIVNSTETNVWCET
PPA------PLPPG--APAPVEVWAGSRPFPHQPLP SLVGKGFIFTYEMAATPVVTATRG
EITNHSLRLYVEGQNLSNSEVLLGNLSCDVETQSP------------SSNTSLSGCAFPL
HSLEAGIYPLQVRQRQMGFADMSAVPQQFVVL PQITAISPTLGSTCGGTVLTVRGL-ALN
SSRRSVQVDIS--GPFTCVILSLGDQAVLCRITPVGNPVPG-----ASFTL----NVTVL
VNGLPSACQGNCTLFLCEETTPVMDAWTTSISGSLTTVLIRGQRLGTAADEPMVFVDDRL
PCTVTSFNTT-HVACCISGLAPGHHYLSVLHTRYGYACSGXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXQCAVPAGNGSVALVIEVDG
LSYQVGVIGYSDAFTPELLSVSQTDD-VSTFSVAGISGAANVDIFIGMFPCVGVSG----
NRTLLQCVVPSLPVGEYQVRGYDHLRGWASSILVFTSRVTVTAVTENFG-CLGGRLVHVF
GAGFSPENISAAVCGAPCQVLANATVSAFSCLVLPLDVSLAFLCGLRPEEENCETSGCSY
VQCDLTVAVGTESLPESWPYFYTCEESSRCICAQDRWTE---SVFPS-FSGLFISPKVER
DEVLIYNSSCTITMETEAKMECETPNQPITAKITEIQKSWGQNTQGNFPFQFCRRWSRSH
SWFPERLPQEGDNVTVEKGQLLLLDTNTSIL-NFLHVKXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
YSHNSTENWVAGELHVLKVMVVLLSRSVTIQGNLTDERVQLLASCQRANASQGDLQNCLY
FKSEKMLGSRDLGARVVIQSFPKEPSWVQLKGVQFRDLGQAFCKHVSSLTVVGA--LRGS
YMQGCTVWRSF-SRGLSMSRTLGLKVDSNVFYDILGHTLLVGTPPEIRYI-----PWEVI
--PGRENDWSEQGNIIRNNVIISVSGAEGLSSTEMMTPSGIYIRDPTNVVEGNRVCAAGY
GYFFHLVTNQTSQAPLLSFTRNSAHACTRCGLFVYPKFQPTWDNGTGPTLFQSFTVWGSA
GGAQX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---GSLCMSA
GIKTPKRWELTVSNTTFVNFDLTDCVAIRTCSGCSRGQGGFTVKTNQL--KFTNSPNLVA
FPFPHAAILEDLDGSLSGKNRSHVLASMETLPASCLVKASFSQLVHGSVCEENVLFHRMS
IGLANAPKVSYDLTITDSRNKTTTVSYVHDTLSNPYGWMALLLDQETYSLRFE-SPWTN-
SSLQYSATFENFAPGNYLLLVHTD-LWPYP---DILIRCGSQVGRSLPSLPSPGRDQGCD
WFFHSQLRQLTYLVSGEGQVQVILQVREGV-APTISSSSSAPESVLKWSLPEAWEGMEKG
WGG--HSGTIPGPGDDVLILPNRTVLVDTDLPSLRGLYVMGTLEFPVDRSNILSLACMLI
AGGELKV--GTLENPLEKEKKLLILLRASEGVFCDRFIGIRIDPGTIGVFGKLQLHSAYP
KKSWTHLGADIASGNERIIVENTVDWRPQDKIVLSSSSYEPHEAEVLTVKEVRGHHVSIR
ERLRHRHVGSVHVMEDGRHIRLASEVGLLTRNIQIQGDTSCGGRLLVGSFRKSSVEEFSG
ILQLFN---VEIQNFGSPLYSSIELTDTSAGSWIISCTLHQSCGGGIRAAASQGIVLNDN
VVFSTAGHGIDLEGQDYSLSNNLVVLMTQSAWSPIWVAGIKVNQAKDIHLHGNVVAGSER
LGFHIRGYRCSSPEALWSDNVAHSSLHGLHLYKETGLDNCTSISGFLAFKNFDYGAMLHV
EHGMEIENLTLVDNTIGLLAVVYVSSAPQCYSENLQIVVRNSVIVATSSSFDCIQDRVKP
RSANVTSPDRAPSNPRGGRVGILWPVFTSEPNRWPQEPWHKV-RSGHLISGIMKLQ-DVT
FSGFVKSCYSDDLDVCILSSAENTGIVPLITAERTRMLKIKDKNKFYFPPLQT-RKDLGI
LVCSESDCESPRKYLFKDLDGRALGLPPPVSVFPKIEAEWTGSFFN--TGTFREEQKCTY
RSLMQGYICKQTDQVILILDSADATWAMQKLYPVVSVTSGFVDTFSSVNANTPCSTSGSV
SAFYSILPTKEITKVCFVDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPNVFLGERFIT
PTQVQSTSSLLNGSIGANYFSIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMFSVLEKGW
EMMTLERLTDFLQVSQDQIRFIHEMPGNEATLKAMADRRAKRKRNCPTVTCASH-D-RVG
QRRLLMMEMSS-YRVLPPTTMETISKVMVVEIGDLPAVRNTGVIPSLSSNKLQTLAHQVI
TAQQTGVLENVLNMTIGALLV-TQSKGVIG---YGNTSNFETGNLIYIRPYGLSVLVQPS
DGEVGKELTVQPQLVFLDKQNRRVESLGPPSEPWVISVSLEGTSDSMLR--GCT-QAETQ
DGYVRFSNLAVLISGSNWHFIFTVTFPP-GVNFTARSRLFAVLPATPSERPTIILAASLC
SGVSWLALCCLVCCWFKKSKS--RKIKSEEISESQTNDQKN----H-SHVSPKR------
QESQVE-TEKEGTMMAEDLRMKVMLG-KL-NQLPHQ-SRNGVSRRKVSRRAVQEE-----
-----EAAVPAPGTTSVTSHGN-TCALGSPAQQLYLQETGSWKEAQEQVLRYQLSG--QD
QLLL-PCPDLRRETQRLQ-GRSRLGKEHGSLGLPQEKPASCSAAEASCLHSVRPEAVQGQ
L-------------------------

--RGLDWLVSPS----SEAWVVFAVSATGLLIKPREGSIAGGTWITITLDEL-GLEISSL
LPSSWSHLEVSLVN-----PDLPSLPCDVSPVY--FGLPSIRCRTR-----SSPQEGLYY
VEVAFKGRAINNLTGVEKENYT FKFSTAQTPVVYQISPPSGIPGNLIEIYGKTIAGRYET
LDFNVDYIDGPAILTA---------EGDGWISLCSFADRQTGSIYPIQADEGVGTMRCRV
EGNH-IGSHNVSFSVFNKGK-SAVHKD-AWLISAKQE----LFLYQIH SEIASVFPAGGS
LGGGTDLTITGDYFEEPVQVTSAGVPCKVKHV--SPQQIICTTEPVGKGRRLGAPQPGNR
GLLFEVWDDA--SDLTEAGPGYRWQFVPNASSPVRFLSAAKHSFSSRLRGFFVAPQTNNY
TFWIQADGQASLYLSLSEDPGNKV-RIASIPAGNSEWSGNWVKNW----SESWQPKSQKF
ELTGGLRYYLEALHHGKTPSNGMRVGVQIHNTWLNPQVVNSYYRERHEIRARALHLPEVQ
MLTVTG-TGWFSISGNNVLRKMIHTNATAQQVQTAIEELLSVGCDTEPTSAKILFRDGFE
KGTRA-SVTTGHVVSGTEPFCGRFSIRRPSQLVKTSPSTLTRYDLTEYTHVCFAHKGHMS
RIFRISVSYTNVSLCSVKRNLTCLWDF----NETDHKSWMFTCTNVWRGCVNHSMLLQDL
PATSPVFVHQIDLLSPTLQKETPGSFYLDEVIITDRAVTVSQRDPKPPWLGGRIIEAVTV
VGSSPTYNVSWLASGCGASLPLLSLRSGKKKNSGKEDVRV---------SVITQRLQKSS
PPIGGTFRVHLAS-TVISGVSVHISSHHLRKLLQDNTDNSTAPYFKASDFVVTKDSNSCY
ESIWTLTWKRKTGDLPNVISVHQVSAENLTGLKPTISSRVIYDGGVFIGPIFGDMLATFN
NQTQVVVVVNDVPANCSGLCSFQFSQEMTPLVSDVEYSSDDGS---QATVVIRGVGFTEQ
NTTLQVEVNNTTCHIITLNQTEVVCNMERLPVGVYLLTLLVRPYGFA LNASTGEGIFLRV
E PKLVA-IEPPRASEIGGLRVALRGTGLEGVNLVLFGSQPCPILDNARNSTRIECKVPSR
GAED-TAVHVTLVSGYQSTTVTNLFQYDPSLNPTVVSLSRNRSGIA--GGQELQIGISS-
-FTSFRGADVKVQIGHSWAQIQAQTDHGVNVTLPALAAGWYNVSVIINGVAVTSNRAELL
IHYVSEIFSIEPCCGSFLGGTLLTISGVGFSRNLSLISVSMNRQTCLVTRLEEETIWCLT
PPAADLLN-EDSQD--TSVRVNVLISSSSLQHVS---VAKNITTFLYQRALTPVITSVET
EITAISLLLSIQGINITGSMAKLGDNECELEFQHG------------NESALFYECSLPL
DNLEPETYPVRVIQRQLGYACVAARLQTLTVT PRITSISPSQGSVCGGMLLTIDGV-ALK
SRRNRVQVSLD--GNYSCEIQSSDNDAIHCIVLPGAQLLPYNQLAESSWAL----NVTVT
VNGISSVCLGDCTLH LHEQST PLVDLVAWETNGTFTYVTITGQRLAWPSDSPMVHVNNQA
VCKVTFWNET-SIKCQIDCLAPGEYNISISNRRSGQACFR RAAG-VTIT PQVHRFYPQNF
STNGGGLLTLAGSALRGKNRTSVFIDYLPCLVLSV-TCVAIQCTVPPGNGTRALRLTVDG
TSYGIGSISYSEESTPTFLSLVSTG-LLLMMNVSQVTEMDTIHVFIGNSACGGVTI----
ARSTLQCSAPPLPAGEYPVLGLDVPRGWASSNLTFTSQLVVTAAYHNWG-GLAGGAVHLR
GTGFDPGQTSVTICGAPCEMLDNATTTDLSCLAPRLHASLAILCGLTHSSTDCREDRSTF
IECDIQVTVGPYQQQGSVSYLYLCEDSRPQ------WHQRDSDSSRRHLAGLFSSPKVER
DEVLIYNSSCNITMETEAEMECEGANQPITAKITEIWKNWGQNTQNNLALRFCGRWAEDS
SWPAGHPPRDGDSVTIEEGRTLLLGTTTATL-NLLHLQGGKLLFTGPGPVELHAHSILIS
DGGELQVGSSEAPFHHKAHIYLYGSLHSPPIFPYGAKFLAVRNGTLSIHGWMPKVAFTQL
KSSVLANDTRLVLQEHVDWHPGDEII-VGRTGLGDVQQQEEMAIIESVNNTVIYLRSPLR
YSHNVGEERVNGQSLPLTAVVALISRRVVVQGNVTRERRAHLRECAKAGVARGEEKNCLY
KRSERQLGSRDLGAIVIVEAFQEEASRLQVEGVQFRHMGQTFGWHHSALTVAGDAQMADS
YIRGCSVLDSV-GQGLHLAGISNLSVDSNVFYNISGHGLLLALPDIYSAGLILVTSLTQI
MDTVH--ARLEKGNRIRNNLVIGLSGTDGLSNIETLSPAGIYVRAPANHIEGNTVCAAGY
GYLFHLSPEGPSKMPLLSFSENVAHSCTRHGLLVYPEYLPDS--PNGPVQFNSFTAWSSQ
GGAQI-FRSSNLILQSFRIYACTDFGIDIVESLGNTSVANSFLIGHIGQK---GGTCMSA
GLKTPKRYQLLISNTAFRNFDIDTCTAIRTCSGCYQGQGGFTVRAEHL--TFTNSPFQVS
FPFPHSAILEDLDGSVTGQEGSRLLPSTDILGASCTASANFSQASGGSVCGRDLVFHRMS
LHLKEAPDIPYNLTVTDSRNKTTTVNYVPDTLSNPYGWMVLLLDKETYTLTFD-NPLVS-
KQLQYSVTFSNFTTGNYLLVEHKD-LPAHS---EVIVSCGNRTGQPLQSLPSYGHHGNCD
WYFDSRLRKLTYLGSGCTGMTLFFQLNKIHP--TSVVSTVPSDAVLKWSHPETWKDVEKG
WGG--FNCSIPGPGEDVIILPNRTILVDTDLPPLRGLYVLGTLEFPTNASNVLSAACIVV
VGGMLKV--GSFQHPLKQDLKLLILLRASEGIYCDRLEEINVHPGSIGVYGKVQIYSGYP
GKSWTHLGGNVAPGNDRILVEDEVDWSPGGDIVVSSSSYEAHQAEVVTLKEVNGRSIALH
ERLLHRHIGHFHDTEDSRRIRLAAEVGLLTRNIQIKSDLACTGRMLVGHFMDSSGREFEG
VLQLSN---IEFLNFGPPQLSVIEFRNISQQSSVVSSSIHGSCGGGIKAIMSNWIVLHDN
MVFNTVGPGIDLEGQSHSLIKNLVILSRQPEGLLNWVAGIKVNLAIGVSLYGNVVAGSER
IGFHIRGQDCLLDGEYCSENVAHSNLHGIHLYRGDGFPTCTRITGFLSYKNYDYGMMFHL
GSSVVIDNVVLVDNTVGLMPVLYCLYAKQCHTGKRFLELRDSVIVATSSTFDCISDRIKP
HAADLTSRDRPPYYPRRGRVGILWPTFTTMPSQRPENAWHKI-VHCPKVLGLMKLK-DVT
FTGFTKSCHSEDRDVCIMSNADHLGIMPLITAERSRMLHVNEKDKFYFHPAS--VQSSED
TMFPEKSCKGSRKALFKDLDGSVLDLEPPVSVFPKSEFEWTQFYLQ--AGIYRDDKKCIF
KPSVQGYFCKQADHALVILENLDTTVVNQELFPVVAETDNFMDTFS----DASCYPAEHP
STFFSVLPSTKVTTVCFPDLTPLIFRLSLLSGQNSTRLPLAIFYNEPLSLRVFVQGKYVS
PTPS---SFSQKEGAGANYFSFKDNLLYVLLHEKEPVEIVAGLSLHIAFTVSEAIGEEGQ
-ANIMHQLADFLQVGHDQIRVVHHIPGGESMLKVISDNASKKKYHCPNMTFCTAFHSRSG
SQKMGRAPVST--RALQPSDAPGPSRVLIIELGDLPGHQRNEFQRTLTIDSLKTLARTII
NAHQTGDLDLPEEITVGNLMV-TSARG---LRWKKNGSRQHPGTWLYVRPYNLSVRVQPS
DGEIGKQLPVQPQIIFLDKKGRRVEELGPPSEPWIVSAHLKGSSEAVLK--GLT-EVQVI
DGCASFSSLAVSSSGTNYNLVFTVTSPP-GAKFTVLSHPFTIFPVPMGEKASLILVVLLS
AVASAFV-LTLVFCWFKKSKS---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

-------MAVVLISLMSIELLLLAXXXXXXXXXXXXXXXXXXXXXXXXXXXLE---TSVL
YPTNGSQLEIHLVNR--VVPTLPSIPCDVTPVF--LTLPVVTCQTRSLL--SEAHAGQYS
LEVHYGGQVFYSPSPGSKDNCTFKFSKAQTPIVYHVNPSSGVPGNLIYVHGWIFTGKLET
FDFDDEYIDSPLLLES---------QGDKWVTPCSLINRQTGSRYPIQEDHGLGTLQCRV
EGDY-IXXXXXXXXXXXXXX-SMVHKN-AWLISAKQD----LFLYQTHAGILSVFPETGS
IGGRTDITITGDFFDNSTHVTVAGIPCDVRHV--SPRKIECATRAPGKGVRLTAPQAXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXASSPIRFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWTEEPKTKV-KMAFIKAGNADWFDFWEQNG---NEGTWQQKTPKL
ELLGGARYYLEAEHVGVSPSKGMRIGVQIHNTWLNPDVVPTYLREKHQIRVQVQRLPEIQ
TLNVSG-RGSFSLTWDSVSSQPIVANATAYQIQTAMEELLA---ECEPHSANILIHLRFQ
QGL-EGSLSDGHPTSGTEPFCGRFSLHQPKYLVITPPATQKGHWLDQRTHLCIAYKGHTN
RILKMTVFFTLGSQNIV-KNTSCDWSL----SGINPNSWQFKCKNLWETCVCRFHGLQPP
LANSPLMVRRIELLPLA----EKGVLYVDEVIIADTNITVSQAGSGTARPGGNLVESISV
TGSPPVYSIASWLAECGMELPLIIARSVPTNGTEK---------GIGPVQWTAQRLQRTS
PPLGGHFRIHLPNDAVIPDVSVHISANRLQKLLESNADNFTSRFLHVSDFTVEEQPNSCY
ERVWTLSWSTQIGDLPNFIK---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXVVVRVNDIPAQCLGSCSFRFLPESTPYIYSVEYSIDHDI---NLLIYINGTGFSDD
SKALQVTVNNTNCEVVFSNQTDVVCRTDLLPVGTHQVSMLVRPCGLAVSASG-EDL LLKV
E PRLDA-VEPSRAAEIGGIWATIRGSSLEGVSLVLFGSQSCAINVTTSSSHRIECKVPSR
GKDG-HVVNVTVISGDYTAVLPNVFT FASSLN PEILFLSRNHSGIA--GGGRLFIRMTQ-
-LASYTGLDITVHIQDALAQIHAQTAQGLEVVLPPLPAGIYEVSVSINGISIFSRGVDLH
IRYLTDVYSIRPCCGSFLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX-XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX----XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXSGAVNVDVI--GPSCGGISG----
DHTTLHCTAPLLPVGQYPVTAYDRPRGWASSALVFTSRVRVSAVTQNFG-CLAGGLVHVF
GAGFSPGNISAAVCGVPCQVLANATVSAFSCLVLPLDASLAFLCDLRPEEDSCDDASLTS
VQCQLTVAVGVERLPESWPYFYMCEECSQSRFGSAPG-----TAFPS-FSGLFVXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDNFSFRFCRRWSRAH
SWLPGRVPQDGDNVTVENGQVLLLDCSTNIL-NLLHIKGGKLVFVGTGTVDLRAHAILVS
DGGELRIGSEDKPFQGRARIKLYGSSYSTRFFPYGVKFLAVRNGTLSLHGLLPEVLVTRL
RATAHAQDTVLALEDAVDWHPGDEVVIISGTSVEGTKPVEEIVVVETVHNAELHLRSPLR
YSYSFTENWAAGQYSVLKATVALLSRRITIQGNLTLERKKLLASCQEASASEXXXXXXXX
XXXXXXXXXXXXXXXXXXQSFQEEASQVQLKGVQFRDLGQSFHKHLSALTLVGS--VKDS
YVQGCTVWNSF-SRGLSMDSVLGLKVDSNVFFNIVGHTLLVGAYMEARPI-----AWEVI
TRRNY--DWSEQGNIIKNNVIISVSGAEGLSSSEMLTPSGIYIRNPTNVIEXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXCGLFVYSRFQPPWNNGPGPTLLQYFTVWESV
GGVQI-FRSSNLRLKSFRIYSCRDFGIDILENDANTSVTDSLLVGRFTHQ---ESKCMSA
GIKTPKRWELTISNTTFANFDLVSCVAIRTCSGCSQGQXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXADAPSVPYGLTLTDSRNKTTTVNYVGNTLSNLHGWMALLLDQETYSLRFE-NPSVH-
RSLQYSASFDNFTQGNYLLLVHTD-VPLYP---DILISCNSKVGRALLSRPSPGRDQSCD
WFFNRQWRQLTYLVSGEGQVQVIFQVREGV-PPSVAXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXRTVLVDTELPFLKGLYVMGTLEFPVDRSNVLSMACMVI
VGGELKV--GTSENPLEKEQTLLILLRTSERVFCDRFNGFQIDPGIIXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXIIVEDTVDWQPHDKIILTSSSYEPHEAEVLTVREVKGHHIRIY
EQLKHRHLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
VLQVSN---VEIHNFGTPLYASIEFINVSTGSWIISSALHHSCGGGIHALASHSIILNDN
IVFDAAGHGIDLEGQDYSLTNNLVVLMAQSALSTVWVAGIKVNQAKDVNLLGNVVAGSER
LGFHLGGHRCSSPGVIWSGNVAHSNLHGLHLYKKSETENCTSISGFLAFKNFDYGAMLHV
KNSMEIENIILVDNTVGLFVLVYVS-FPQNSNKDTRIVFRNSDVVATSSTFDCIQDRVKP
RSAIMTSRDRAPSNPRGGRVGILWPAFTSEPNLWPQEPWHKV-RDGYSVSGVIKLQ-GVT
FSNFGKSCYSEDLDICILPNEQNTGIIHPITAERTRMLNMKDKNKFYFPPLQP-RKDLER
IICLESHCENPRKYLFKDLDGNALNLPPPVSVFPKLEAEWTGSFFN--TGTFREKKKCTY
HSLIQGFLCKETDQVVLVLDNVDVSSSIQKLYPVVSITNGFVDTFTSANANTPCSSSRSG
LTFYSILPTEQLTKVCFMDQTPPILHFYLLGNKSYSKLLLAIFYHELQSPQVFLQGTFIP
PTFIKSDSSLLDEPIGTNYFNIMDNFLYIVLQGEEPVEIHTGVSIHLAFTVRFAVVENSW
EILMLEKLIDFLHIDQNQIRVVHKIPGNEETLETIADIAAKRRRNCPTVACTNH-YVRVG
QRRPLMMELNSSPQASVPPTVETVSTVIVIEIGDLTTVWNTGLFPSLSRNKLQNLTDQLI
IAQQTGVLKNVLNMTTGALLV-TQSKEVIG---YGNASIFKSKNIIYVQPSALVVLVQPS
DGEVGKELPVQPKLIFVDEQNRRVESLGPLSEPWTVAVSLEGRLNSVLK--GYT-QVETQ
DGYVSFSNLAISISGSNWHFIFTVTSPP-GVNFTARSRKFAVLPVTMKETSTIILAASLC
SVASWLALSCLVCCWFKKNKN--RKTKPEETSESQTNDQKN----H-TPVXXXX------
XXXX-X-XXXXXXXXXXXMRMKVMLG-KL-NQLPHQ-SLNGVSRRKVNRPTVGH------
----KKTAVPVSGIVGVTSQGH-TCTPIAPAQQVHMQESGNWKEAKEQLLRYQLAR--QD
QLLL-LCPDLRQG-------QGQQTKESGSLGPSQETKISCGATKEICLHSVHPETIPEQ
L-------------------------

-------MTGSLIYLTSIKILLLAVPCLNIHIEPEEGSLAGGTWITVIFDGLE---LGLL
HPANGSQLEIHLVN--VALPTLPSIPCDVSPVF--LDVPAVMCRTRSLL--PEAQEGVYS
LEVQAGGQVVGSPHPGPQDSCTFKFSRAQTPIVYQVNPASGVPGKLIHVYGWIITGRSET
FDFDAEYIDSPLILEA---------QGDKWITPCSLVNRQTGSRYPIQEDHGLGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SVIHKD-AWLVSAKQD----LFLYQTYSEILSVFPETGS
LGGRTDITITGDFFDNPAQVTIAGIPCDIRHV--SPRRIECTTRAPSKGARLSAPQAGNR
GLLFEVGDASEDLDLTEATPGYSWQIAPNASSPSGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADNQASLYFSWSEDLRTKV-KMASIRVGTADWFDSWEQNG---SDKTQQQKTPKL
ELRGGARYYLEAEHRGTAPSSGVRIGVQIHNTWLNPDVVSTYLREKHQIRAWAQRLPEIQ
MLTVSG-TGNFFLTWDNVSSQPIPANATAHQIQTAVEELLAVKCKLEPLAANILLWQGFE
QGL-EGSTSDGHLTSGTEPFCGRFSLHQPRHLVLTPPAAQKVYRLDQYTHLCLAYRGHEN
TTLKMTVSFTVGLQNPV-KNLTCDWSL----LGTSPRCWQFTCTDLWKTCVRHSSHLQLP
PANSPVLVHQIDLLPLS---PEMGMFFVDEIIIADTNLTVSQADTGTARPGGNLLESLSV
VGSPPVYNVTSWLAGCGLELPLITASAVPTEGAEE---------GSGLVQVTTRRLQRTS
PPLGGHFRIQLSN-TAIPGVPVHISASHLQKLLQTSADDFTSRYLNVSDFTVTEDLKSCY
EHVWTFSWSSQVGDLPNFIK---VSNENLTGVNPAVITRVVYDGGIFLGPIFGDMLVTAN
RYTQVAVRVNDIPAYCSGSCAFQYLEGSTPQVYSVWYALANAV---GLLVYITGTSFSGD
YKALQVTVNKTSCKVIFSNQTNVVCQTSLLPVGVHQILMLV RPSGLAINASG-GGLFLNV
E PRLDA-VEPSRAADIGGLWATVRGSGLDNVNLVLFGSQSCVINVTTSSSQRIQCKVPSK
GEDG-PTVNVTVILGGRSVVLAMAFTYVSSLNPVIVSLSRNGSGIA--GGEIISIGMVL-
-PVNHTDLDAEVRIGDTRAWVQAQTAQGLEVVLPPLPAGLHGISVSINGVHIHAQGVDLH
IQYITEVFSIQPRCGSLVGGTILSISGRGFSRDRALLWVLVGSRSCDIVNSTETSVWCET
PPPAPLPPPPLPLS--APVPVE VWAGSKPFPHRPSPRLVGKGFTFMYEVAATPVVTVMRG
EVANQSLRLYVEGQNLSDSVVLLGNLSCDLQTPSP------------GSNLSLAGCTFSL
DTLEAGLYPLQIHQRQMGFADMSAVPRQWVVM PQITAVFPTRGSTCGGTVLTVRGL-AFR
SSRGSVEVDLS--GPFTCVILSFGDQTVLCRITPVGDPLPG-----ASFTL----NVTVL
VNG LPSMCQGNCTLFLCEETTPIMDDWTT NISGSLTTVLVRGQRLGITADEPVVFVDDRL
ACTVTFHNAS-HVACWISDLSPGPHYLSVLHA RYGYACSSNFSRHFHVWPQVF HYFPKNV
SLHGGSLLTLEGTALKGLNSTLVYIGQQACLTVSL-GSELIQCAVPAGNGSAALDIEVD G
ASYQMGVIGYSSAFTPELLSVSQSDD-VLTFSVARISGAANIDIFIGMSPCVGVSG----
NHTLLHCVVPSLPTGEYQVRGYDRMRGWASSVLVFTSRVTITAVTENFG-RLGGRLVHVF
GTGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDVSLASLCDLRPEEEDCETSSCSY
IHCDLTITVGTESLPESWPYFYICEESSRCLLARDHWTE---STLPS-FSGLFISPKVER
DEVLIYNSSCTITMETEAKMECETPNQPITAKITEIRKSRGQNTQGNFIFQFCGRWSRA H
SWFPKRPPQEGDNVTVEKGQLLLLDTNTSIL-NFLHVKGGKLIFLDLGPLELRTHSILVS
DGGELRIGSEDKPFQGKARIKLYGSSYSARFFPYGVKFLAVRNGTLSLHGSLPEVVVTHL
RATANAHDTVLALEDAVDWHAGDEVLVISGMRAEGAKPKEEIVTVETAHSTDLQLRSPLR
YSHNSTENWVAGEHHVLKVMLVLLSRSITIQGNLTDERVQFLASCQGASASEGDLQNCLY
SKSEKMLGSRDLGARVIVQSFPEEPSQVQLKGVQFRDLGQAFHEHVSSLMLIGA--MRGS
YLQGCTVWQSF-SRGLSMSQTSSLKVDSNVFYDISGHALLVGTSPKIRYI-----PWEVI
--PGGEKGWSEQGNIIRNNVIIRVSGAEGLSSPEVVTPSGIYIRHPTNVIEGNRVFAAGY
GYFFHLVTNKTSQAPLLSFTRNSAHSCTRSGLFVYPKFQPPWDNSTGSTLFQNFTVWGSA
GGAQI-FRSSNLHLKNFQVYACRDFGIDVLESDANTSITDSLLLGHFAHR---GNLCMSA
GIKSPRRWELRVSNTTFVNFDLTHCVAIRTCSGCSQGQGGFTVKTNQL--KFVNSPNLVA
FPSPHAAILEDLDGSLSGKNRSHILASMETLPASCVVKASFSQLVHGSVCEENVLFHRMS
IGLANALNISHDLTITDSRNKTTTVSYVHDTLSNPYGWMALLLDQETYSLRFK-NPWAS-
SALQYSATFDNFAPGNYLLLVHTD-VWVYP---DILIRCGSHVGRSLSSLPSPGRDQGCD
WFFDSQLRQLTYLVSGEGQVKVVLQVRKGV-GPTISASTSVPKSVLKWSLPETWEGVAEG
WGG--HSGASPGPGEDVLILSNRTVLVDTDLPPLRGLYVMGTLEFPVDRSNILSVACMLI
AGGELRV--GTSENPLEKEKKLLIHLRASEGVFCDRFNGIHIDPGTVGVFGKVQLHSAYP
KKSWTRLGADIASGNERIIVEDTVDWRPHDKIVLSSSSYEPHEAEVLTVKEVRGHHIRIH
ERLRHRHIGSAHFMEGGRHIRLAAEVGLLTRNIQIQGDTPCRGRLLVGSFRKSSVEEFSG
ILQLFN---VEIQNFGSPLHSSIELTNVSAGSWIISSSLHQSCGGGIHAAASQGVILNDN
VVFSTAGHGIDLEGQDYSLSKNLVVLMTQSAWSPVWVAGIKVNKAKNTHLHGNVVAGSER
LGFHIQGHRCSSPESLWSDNVAHSSLHGLHLYKGSGLVNCTGISGFLAFKNFDYGAMLQV
ENSMEIENLTLVDNTVGLFTAVYVSSAPRCYIRNLQIVLRNSVIVATSSSFDCIQDRVKP
HSANLTSPDRAPSNPKGGRVGMLWPVFTSEPNRWPQEPWHKV-RNGHLISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIVPPIMAERTSMLKIKDKNKFYFPPLQT-RKDLET
LVCSESDCESPGKYLFKDLDGRALGLPPPVSVFPKTEAEWTGSFFN--TGIFREEQKCTY
RPLINGYICKQTDQVILILDSADTTWAMQKLYPVVSVTSGFVDTFSSINASAPCSISRSV
SAFYSIVPTRKITKVCFVDQTPRVLHFFLLGNKNTSKLLLAVFYHELQSPYVFLGDRFIP
PTQVHSASSLLNESIGANYFSITDNLLYVVLQGEEPIEIQSSVSIHLALNVMFSVLEKGW
EIMILERLTVFLQISQDQIRFIHQMPGNEATLKAMADSRAKRKRNCPTVTCTSH-D-RVG
QRRPLMVEMSS-YRDLPPTTMETISKVMVIEIGDLPTVRNAGLIPSLSSNKLQNLAHQVI
IAQQTGLLESVLNMTIGALLV-TQSKGVIG---YGNTSSFKTGNLIYIRPYSLSVLVQPS
DGEVGKELTIQPQLVFLDKQNRRVESLGPPSEPWVISVSLEGTLDSVLR--GCT-HAGTQ
DGYVSFSNLAVLISGSNWHFIFTVISPPAGVNFTARSRSFAVLPVTPSERPTIIMAASLC
SGVSWLALCCLVCCWFKKSKT--RKIKNEEISETQTNDQRN----H-SHVSPKH------
QGSQVE-TEKEVTRMAEDLRMKVMLA-KL-NQLPHQ-SLNGVSRRKVSHRVVREEG----
-GSREEATVPAPSIASVTSHRN-TCTPGSPAQQECLQESRGWKGAQEQVLRYQLAG--QD
QLLL-LCPDLRRERQRLQ-GQSQLGKGHISLELSQEKPGSCGATEAFCLHSVHPEAVQEQ
L-------------------------

-------MTAWLISLMSIEVLLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGVL
YPNNGSQLEIHLVNMNMVAPALPSIPCDVFPVF--LDLPVVMCQTRSLL--SEAHEGLYS
LEAYFGGQLVSSPSPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMIHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRHV--SPKKIECTTRAPGKDARLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNT---DERTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
RGL-EVSNSDGDLTSGTEPFCGRFSLHQPRHLVVTPPAAQKGYRLDQYTHLCLAYKGHMN
KILQMTVSFTIGFQNMV-KNTTCDWSL----TRTSPKSWQFHCTDLWETCVRCSGDLQPP
PTNSPVLVHQIDLVPLA---QETGLFYVDEIIIADTNVTVSQADSGTARPGENLVESVSV
VGSPPVYSVTSWLAGCGTELPLITAHSVPTEGTEE---------GSGLVLATTQRQQRTS
PPLGGHFRIQLPN-TVISDVPVQISAHQLHQLLQNNADDFTSRYLNASDFSVKEDLYTCY
EHVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKTNCKVIFSNQTNVVCQTDLPPVGVHRILMLVR PSGLAIRATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRILCKVPPR
GKDG-HIVNVTVIRGNHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGDTLVIGVAR-
-LVSYTDLDVEVHIQDALALVHTQSAWGLEVALPALPAGLHRISVSINGISIHSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRSFAHGPSPSLVGNGFIFMYEAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSVPL
HSLEAGIYPLQVRQKQMGFANMSAVPQQFAVTPRIMAIFPSQGSACGGTILTVRGL-LLN
SRMRSVQVDLS--GPFTCVILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGITSECH GNCTLFVREETSPVMDTL STSTSGSLTTVLIRGQRLGTTADEPMVFVDDQL
LCNVTFFNAS-HVACQTRDLAPGPHYLSVFYTRNGYACSG NVSRHFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIQCIVPTGNGSAALEIEVD G
LWYHIGVIGYSNAFTPELISISQSDG-ILTFAVAQISGAANIDIFIGMSPCMGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCSLKHEEDSCEAARHTY
VQCDLTVAVGTERMLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDTVLALEDAVDWHPGDEVIIISGTGVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHRILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRSSF-SR GLSMCGTLGLKVNSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCARYGLFVYPKFQPPWNKVTGTTLFQSFTVWESA
GGAQI-FRSSNLRLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSRGQGGFTVKTSQL--KFVNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLANAPEVSYDLTMTDSRNKTTTVNYVRDTLSNPHGWMALLLDQETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILRVKEGM-PPTISASTSAPESTLKWSLPETWQGVGEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLEKPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYP
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIILSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGTVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSAGSWIISSTLHRSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHRCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRTGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDVGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
RFLMQGFICKQTDQVVLILDSTDATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFIHEIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVG
QRRPLMMEMNS-HRSSPPTTVETISKVIVIEIGDLPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENILNITIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYALSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLR--GCT-QAETQ
DGYVSFYNLAVLVSGSNWHFIFTVTSPP-GVNFTARSQSFAVLPVTRKEESTIILAASLS
SVASWLALSCLVCCWLKRSR--SRKTKPEEIPESQTNNENN----H-IHTSSKR------
RESQ-G-PKKEDAVVAEDMRMKVVPG-RL-NQCPHE-LMNGVSRRKVSR-----HT----
-VREEEAAVPAPGTTGITSHGH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL-------QERQQLP-GQSWLSKQSGRLGLSQEKKASCGATEAFCLHSVHLEAIQEQ
LSSGKVWAFGLKGRIFQILLDNKQGK

------TMTGWVSLLISVEALLLSVPHLSLHIEPEEGSLAGGTWITVALDGLD---SSVL
YSSNGSQLEISLVNV--AEPALPRVPCDVSPVF--LDAPVVMCQTRSLP--SEAHEGLYA
LEVRSGGQVVGSPGPGPQDNCTFKFSKAQTPVIYQVNPPNGVPGKLVHIYGWIITGRLET
FDIDAEYIDSPLVLEA---------QGEKWITPCSLINRQTGSHYPLQEDHGLGTLTCRV
EGNY-IVL-----------------------LISFSD----LFLYQTHSEVLSVFPETGS
LGGRTHITITGDFFDGSARVTIAGIPCDIGHV--SPRKIECTSRAPGKGARLTAPQAGNR
GLLFEVGDAAEGLELTEANPGYRRQIVPNASSPFGFWSKQGQLFRARLSGFFVAPETNNY
TFWIQADSPASLHFSHSEELRTKA-EVASIRVGTADWFDSWEQNGTWTDEGTWQQKSPKL
ELLGGARYYLEAEHRGIAPSSGMRIGVQIHNTWLNPDVVTTYLREKHQISVRAQRLPEIQ
MLNVSG-RGDFFLTWDNISSQPIPANATAHQIQATIEELLAVKCKLEPLSANTLLRLGFE
QGL-EGASSDGDLTSGTEPFCGRVSLRRPRQLDLIPAAAQKGYRLDQYPHLCMAYKGHRN
MTLRMTVSFIIGFRNITK-NSTCDWSL----TGTSPESWQFACTDLRDVCPRHPGDLQLP
PANAPVLVRHIALLSLA---RETGLLYVDEIIIADTNLTVSQDHSATARPGGNLVESISV
VGSHPVYNVTAWVTGCGTELPLIAACSVPMGGT-E---------DAGPAQVTAQRLQKTG
PPLGGHFRIHLSN-TVIPDVPVHVSAGHLHKLLQDSADDFTSRYLNVSDFTVKEGRNSCY
ERVWTLSWSTQTGDLPSFIE---VSDQNLTGVNPTVAIRVVYDGGVFLGPIFGDMLATAH
QHTQVVVRVNDVPAQCVGSCSFQYLPGSTPRVHSMWYSLDGDT---NLLVYITGTGLSGD
SKTLQVMVNRTSCKIIFSNQTVVVCQADLLPVGVHQVLVLVR PSGLAVNASG-EDLLLYL
E PRLAS-VEPSRAAEIGGLWATIRGSSLEGVSLVLFGSQSCAINVTTRNSRRIQCKVPPR
GLDG-YVVNVTVFSGDHSAVLPGAFTYVSSLNPVIVSLSRNRSSVA--GGESLFIGMAL-
-LGNYADLAVEVHIQDTLVQVHTQTAQGLQVVLPSLPPGHHRLSVCINGIGIHSQGVDLY
IWYTTEVFSIEPCCGSLWGGTILNISGVGFSSDPALVWVLMGNRSCDIVDLTDIHIFCET
PSAPLLSG-ADS----LPVPVEVWAGNVSFVHGPAPSLVGKGFTFTYESAATPVVTAMWE
EITNSSLKFYLEGNHLSDSVVLLGSLKCDLETQSL------------WGNMSLSGCAFPL
HGLEAGIYTIQVRHKHLGLADMSAVPQHFVVMPQMAPIFPMPRLACSGTVFTMRRV-TLN
SRR-SAKVDLL--GPFNHVILSLGDDVVVCQVSLVGEHVAG-----ASLTL----NVTVL
VDGSASKCQGACTVFMQGETTSVMDILTADTNGSLITILMMDQRLDNAAAEPVVSVDNQL
PCDWTSFNAS-YVVCHISSLTPGPHYLSSVHTSNGCVCWGDASKYFSIVPQVFHYYPRNF
SRHGGSLLAIEGTALTGQNTTSVYVGQQACLTVNI-SSELIQCIVPAGNGSVALEIEVD G
TLYRIGVIDYSDAFTPELISVSHIGD-VLTFAVARISGAANVDVFIGTFSCAGVSG----
NSTVIRCMAPFLPAGEYHVRGYDHSRGWASSALVYTVRVTVTAVTENFG-CLGGRLVHVL
GAGFSPGTVSAAVCGSPCRVLANATVSAFSCLVPPLPVSLAFLCDVKPEEDRCEAAVHTY
VRCELTIAVGTQRLAESWPYLYICEESSRCVSSPDQWTE---PDFPS-FSGLFLSPKVEG
DEVLIYNSSCTIAMETEAEMECETPNQPITTKITEIRKSWGQNTQGNFSLQFCLRWSRAH
S WFPDRPPQDGDNVTVEKGRRLLLDRNTSVL-NLLHVKGGKLIFMGPGPIELRAHSILVS
DGGELRIGSEDKPFKGKAQIKLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSRPDVTVTH L
RAAGRAGDTVLALEDAVRWQPGDEVVIVSGTGVEGTSLREETVTVGTVHRADLHLRSPLR
YTHNCTENWLVGERQILKVTVALLSRSITITGNLTQERRKFLASCPET----SNLQHCLY
SKSEKVLGSRDLGARVIIQSFTKEPSRVQLEGVQFRDVGQAFRKHLSSITLVGA--MRAS
YFLSSP-ISSF-SRGLDLGRTWGLEVDSNVFYKILGHALLVGNY-----V-----PWELI
LRRKL--GWS EQGNIIRNNVIISVSGAEGLSSPEMLTPSGIYVGSPTNVIEGNRVYAAGY
GYFFHLVTGQTSKAPLLSFSQNTAHSCTRFGLFVYPKFQPPWDQDTGPTLFQNFVVWGSA
GGAQI-FRSSNLHLRNF QVYSCRDFGIDILENDANTSVTDSLLLGHFTHK---ERLCMSA
GIKTPKRWDLAISNTAFVNFDLIDCVAIRTCSGCSRGQGGFTVKTNNL--KFTNSPHLVA
FPFPHSAVVEDLDGSLSGKNGSHILASMETLPASCSVNANFSRIVQGSVCGEGVLFHRMS
IGLTNAPEVSCDLTITDSKNKTTTVNYVQDTLSNRHGWMALLLDQETYSLQFE-DPCSN-
RSLQYSATFGNFSPGNYLLLVHTD-LPPYP---YILVSCGSRAGRSLPSLPSPGQDQGCD
WFFNSQSRQLSYLVSGEDQVRVNLLVKEGVVPPTISASTSASESALKWSHSEAWQDAKEG
WGG--YNHSIPGPGDDVLILPNKTVLVDTDLPLLKGLYVLGTLEFPVDRSNVLSVACLVI
AGGELKV--GTLENPLEKEQKLQILLRASEGIFCDRLNGIRIDPGTIGVYGKFQLQSAYP
KKSWTHL AADIAPGNDRIIVGDAVDWKSPDRIVLTSSSYEPHEAEVLNVKEVKGHHIRVH
GRLQHRHIGSPHVMEDGRRIHLAAEVGLLTRNIQIRSDTSCSGTLLVGSFRKSPTEEFSG
ALQFLN---VEIWNFGSPLYSSIEFTNVSLGSWML SSTLHQSCGGGIHASASHGIILKDN
IVFDTAGHGIDLEGEAHSLTNNLVALTTQSAWSTTWVAGIKVNQADGVLLHGNVVAGSER
LGFHIQGHKCSS-EVFWSANVAHSNLHGLHLYEQIGSDNCTSVSGFLAFKNFDYGAMVQV
ENSVELENITLVDNSVGLLAAVYVSPAPQHSSKAVQIVIRNSVIVGTSSSFDCILDRRKP
HSANLTSTDRAPPNPKGGRVGILWPVFTSVQNQWPREPFHKV-KNGRSVSGTIKLQ-DVT
FSSFVKSCYSNDLDICILTNSESTGMVHPIIAERTRMLKMRDRNKFYFPPLHP-RKDLER
VICSESDCENPRKYLFKDLDGTALGLPPPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
RPLMQGFICKQTDHVILALDSVDVTWASQKLYPVVSVTTGFVDTFSSINNHTLCATSGSV
STFYSILPTRQITKVCFVDQTPQVLRFILLGNKSTSKLLLGIFYHEIQSPRVFLGGSFIP
PTLVHSASSLLDESVGVNYFSITDNLLYVVVQGEEPIEIRTDVSLHLAFTMTFSSLEKGW
EVVILEKITNFLQIDQNQIRVTHEMPGDERTLKAIADSRAKRKRNCPSVACASH-YRRGG
QRRPLMTEMSS-HRAFPPATAEMSSTVVVIEIGDLPTSTRTGLTPSLSSNTLQTLAHQII
TAQQTGILEHVLNMTVGALLV-TQSKGIIG---YGNSSSFKAGNLIYARPYTLFVLVQPS
DGEVGKELPVQPQLIFLDKQYQRVECLGSPAEPWTVSVSLEGTSDSVLR--GCA-QVKTQ
DGYVSFSNLAVLISGSNWNFIFTVTSPP-GANFTARSRSFAVLPETGKERSTIILAASLC
SVVSWLALSCLVCCWFKRSK--HKKTKPEESSESQTNDQKN----Q-THAPSKW------
RASQIQ-MEKEDSRKAEDMRMKVLPG-RL-HQLPHQ-TLDGVSRRKL-------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

-------MTAWLISLMGVEALLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGVL
YPNNGSQLEIHLVNTNMVAAALPSIPCDVFPVF--LDLPVVTCRTRSLL--SEAHEGLYS
LEAYFGGQLVSSPSPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMVRKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRH--VSPRKIECTTRAPGKDTRLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDFWEQNR---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
GGL-EVSNSDGDLTSGTEPFCGRFSLRQPQHLVVTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWS----LTRTSPKSWQFRCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLVPLV---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLATTQRQQRTS
PPLGGHFRIQLPN-TVISEVPVQISAHHLHQLLQNNADDFTSRYLNASDFSVKEDLYTCY
ERVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKMNCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-HVVNVTVIRGNHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAR-
-LVNYTDLDVEVHIQDALALVHTQSAWGLEVALPALPAGLHRISVSINGISIHSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNQSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRSFARGPSPSLVGNGFTFMYEAAATPVVTAMQG
EITNSSLSLRVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSVPL
HSLEAGIYPLQVRQKQMGFANMSVVPQQFAVTPRIMAIFPSQGSACGGTILTVRGL-LLN
SRTRSVRVDLS--GPFTCEILSLGDHTILCQVSLEGDPFPG-----ASFSL----NVTVL
VNGITSECH GNCTLFIREEASP VMDALSTNTSGSLTTVLIRGERLGTTADEPMVFVDDQL
LCNVTFLNAS-HIVCQTRDLAPGPHYLSVFYTRNGYACSDN VSRHFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIRCIVPTGNGSAALEIEVD G
LWYHIGVIGYSNAFTPELISISQRDG-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKHEEDSCEAARHTY
VQCDLTVAVGTERMLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFVSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQSLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDTVLALEDAVDWHPGDEVVIISGTGVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIIQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLTMVGA--MRES
FIQGCTVRSSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGITLFQSFTVWESA
GGAQI-FRSSNLRLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSRGQGGFTVKTSQL--KFINSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLASAPEVSYDLTMTDSRNKTTTVNYVRDTLSNLHGWMALLLDQETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILWVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYS
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDISCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSEGSWIISSTLHQSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHKCS-CGLLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHI
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
LSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSIFPKTEAEWTASFFN--AGTYREEQKCTY
RFLMQGFVCKQTDQVVLILDGADATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDETPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSSVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGPNQIRFLREIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVS
QRRPLMMEMNS-YRSSPPTTVETMSKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENILNMTIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYVLSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSQSFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKC------
RESQ-G-PKKEDNVVAEDMRMKVMLG-RL-NQCPHQ-LMNGVSRRKVNR-----HI----
-IREEEAAVPAPGTTGITSHGH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL--LPGLRQERQQLP-GQSWLSKQSGRLGLSQEKKASCGATEAFCLHSVHLEAIQEQ
L-------------------------

------TMTGWVISLMSIENV-----------------------------------FNVL
YPNNGSRLEISLVNV--AVPALPSVPCDITPVF--LAVPVVMCQTRSLL--SQAYEGLYS
LEVRSGGQVV-----GPQDNCTFKV------------------GKLIHVYGWIITGKLET
FDTDADYQFSPATSLFILCIPFLIKEPELASRVVLLMSVCFLLSYPFQEDRGLGTLTCRV
EGDY-IGSQNVSFSAFSFFL----------------------------------------
------------------------------------------------------------
----------------------------------------PNTVKARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKVFTLLSFSFDL---------IGEK------LEK--SL
QVM------------------------------CSPEMCRKQKIAQDPGQDGC-HRLRAT
TLTVSG-KGDFSLTWDNISSQPLPANATAHQIQIAIEKLLAVKCKLEPPSANILLRLGFE
QGL-EGSSSRGDLTSGTEPFCGRFSLRQPRHLDLIPPGAQKGYWLDHYPHLCMAYKGHRS
TILRMTVSFIIGFQNIT-KTSTCDWSL----MGISPQSWRFTCTDLWDMCVYRSGNLQMP
LVKASVLVHQISLFSVA---LETGLLYLDEIIIADTNLTVSQDDSATARPGGNLVESVSV
VGSHMAYNITSWVAGCD-------------------------------------------
-------------------VSVHMSAVHLHKLLQDNADDFTSRYLSAGDFTVKEDLNSCY
EHVWTLSWATQVGDLPNFIK---VCLL----------------------SPWGDHMDLVP
WRNFVVVRVNDIPAQCLGSCSFRYLTGATPKVHSMRYSLDGDT---SLLVYITGTGFSDD
SKSFHVVVNKTSCKVIFSNQTIVVCQTDLLPVGVVLYFNLFCSLVDN-----------FC
LPKWACVLYENAIFAAGGLWATIRGSNLEDVSLVLFGCQSCAINVTTRHSRRLQCKVPPR
VSGL-L-------------------WSCLSIWVVIVSLSRNRSNIA--GGETLFIGMAL-
-LENYADLDVEICVQDTLAQAHTWTAQGLRVVLPPRLPGLHTLSVSINGISIHSKGVDLH
IWYITEVFSIEPCCGSLLGGTILNISGVGFSRDPALVWVLVGNQSCDIVDSTETSICCET
PSAPLLSS-AD----SLPVSVEV WTGNVSFIHGPAPSLVGKGFTFMYESATTPVVTAMWE
EITNSSLKFYLEGNHLSNSVILLGNLKCDLETQYF------------GGNVSLSGCAFPF
HSLEAGVYPIQVRHKDMGFANMSAVSQHFAVMPW ISTTIPMHSLACGGTVFTIMGT-PFK
SRKRSIQVDIL--GPFTHVILSLRDDTLVCQVDLVGDHLTG-----AFFTF----NITVL
VKEVDSKCQGNCTVLMQEETSPVMDILAGFAS----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--KIVS-------------------------------------CHSVFKGCLGGSLVHVF
GAGFSPGAISAAVCGAPCHVVANATVSAFSCLVRPLDVSLAFLCGLKREEDGCEAPVHTY
VRCDLTVTVGTQTLAGSWHYLYTCEEGSQCVPVPDWWTE---PGFPS-FSGLFISPKVER
DEVLIYNSSCTITMETEAEMECETPNQPITTKITEIRKSWGQNTQGNFSLQFCLRWSKTH
SWFPGRRPQDGDNVTVEQGQQLLLDTNTSIL-NLLHVKGLDSP-----------------
--------NR--------------------RLPFVACFL------YAAVGSVPEITVTHL
RAVGRAGDTVLALEDAVDWHSGDEVLIVSSTGVGGASLREEIVIVETVHHADLHLRAPLR
YTLDGRPAAC--YRCIMGLNV------------------P-----WASFCVSGNLLHCLY
SKSEKVLGSRDLGARVIIQSFTKEPSRVQLKGVQFRDMGQAFQKHLSSIMVVGA--MRGS
YIQGCTLFLLF-----------------------------SGTHMEIGYI-----PWEFS
PGRKH--GWSEQGNIIRNNMIISVSGAEGLSSPEMLTPSGIYIRSPTNVVEGNRVCAAGY
GYFFHLVNNQTSEAXXXXXXQNTAHFCTRFGLFVYPKFHPPWDHDTGLTMFQNFMVWGSA
GGAQI-FKSSNLHLKNFQVYSCRDFGIDILESDANTSVTDSLLLGHFTHKV--KRLCMSA
GIKTPKRSELMISNTTFVNFNT-----------------------NHL--KFINSPNLVA
FPFPHAAILKDLDGSLSGKDKSHILASMETLPDSCSVNANFSQIVQGSVCGEGVLFHRMS
IGF--APDVFCDLIITDSRNKITTVNYVHDTLSNCYGWMAVLLDQETYSLRFA-DPCIN-
KSLQYSATFDNFSPGSYLLVWIIFCLPANKYFYEILYNIKKHLF-------GRLKSTTCS
FKLGYNLKII----------------KMNQIFLYFLASKAAPKSALKWSLSATWQDVEEG
WGG--HNHTIPGPGADVLILPNKTVLVDTELPFLKGLYVMGTLEFPVDKSNVLSVACLVI
AGGEMKV--GTLENPLEKKQKFLIRLRASEGVFCDRLNGIRIDPGTIGVYGKFQLHGAYP
KKSWTRL AADIAPGNDRIIVEDVVDWKPDDKIVLSSSSYEPHEAEVLSIREVKGHHIRIH
GRLQHRHIGSSHVTEDGKHISLAAEVGLLARNIQIQSDTSCSGTLLVGSLRKSPREEFSG
VLQFLN---VEIWNFGSPLYSSIEFT NVSSESWILSSTLHQNCGGGIRASASHGIILNDN
IVFGTAGHGIDLEGEAYSLTNNLIVLMTQSAWSTTWVAGIKVDQAKDTLLRGNVVAGSER
LGFHIQGHKCSS-EMFWSDNVAHSNLHGLHLYEKVGSDNCTGVSGFLAFKNFDYGAMVQV
ENSVKIENVTLVDNSVGLLAVVQVS-SPQDTIRNVQIVLRNSVIVATSSSFDCILDRTKP
RSASLTSTDRAPPNPKGGRVGILWPVFTSVQNQWPWEPWHKV-KNGHSVSGIMKLQ-DVT
FSSFVKSCYSDDLDICILPNSDSTGMAAPIIAERTRMFKIRDKHKFYFPPLHS-RKNLEG
VICSESDCENPRKYLFKDLDGTALGLPPPVS--PRGGEKWTLLIFHCFIGPFREEQKCTY
RSSVQGFICKQTDQVVLTLDSVXXXXXXXXLHPVVSVTRGFVDTFSSINDNTLCSTSGSV
STFYSILPTRQITRVCFVDQTPQVLRFSLLGNKSTSKLLLAIFYHEIQSPRVFLGRSFIP
PTFVQSASSLLDESIGVNHFSIADNLLYVVLQGEETIEIRTDLSLHLAFSVTFSVLEKGW
EVMILEKLTNFLQIDQSQIRVTHEMPGNERTLKAFADSKAKRKRNCPTVTCASH-YRRAG
QRRPLMTVMSS-YRVFPQTTVETISKLIVIEIGDLPASKKTRQISCLSSYKLQNLAHQVI
TAQQTGVLENVLNIXXGALLV-TQSKGVMG---YINASSFKDRSLIYARPYALFVLVQPS
DGEVVSNCRLPFV-------------------------------LCLFT--GST-QAKTQ
DGYVSFSNLAVLISGSNWSFIFTVTTPP-GANFTARSKSFAVFPETRKERSTIILATSMG
SVVSWLALSCLVCCWFKRSKH--RKTKPEEISESQTNDQKN----Q-IHDSSKW------
QASQIE-PEKEDSRKAEDMRMQVLLG-RL-NRLPHQ-TLDGVSRRKLGHRRA--------
-AREEEAAVPAPS------TGH-TCDPGSSTQQVHPPEN----ETQEQLIRYQQAN--PD
QRLL-LGPHLSQDRQQGQ-GQSPRSADKGGVDLSQEKSTSGHATGTLCLPSAQPEAI---
--------------------------

-------MPIWLISLISIEVVLLAXXXXXXXXXXXXXXXXXXXXXXXXXXXLE---MGLL
YPNNGSQLEINLVNM--AEPALSSIPCDVSPVF--LDLPLVMCQTRSLL--SEAHKGVYH
LEVLSGGQVVSSPRLEPQDNCTFKFSREQTPIVYQVNPPSGVPGELIHVYGQIITGRLET
FDIDAMYIDSPLILEA---------QGDKWVTPCSLINRQTGSCYPVQEYQGLGTLQCRV
EGNY-IGSQNVSFSVFNKGK-SVIHKD-AWLISAKQD----LFLYQTYSEILSVFPETGS
LGGRTDITITGDFFDSPAQVTIAGILCDIRHV--SPRKIECTTRSPGKGARLTAPQAGNR
GLLFEVGDATEDLDLNEATPGYWWQIVPNASSPFGFWSKEGQPFRARLRGFFVAPETNNY
TFWIQADSQASLYLSLSENPGTKM-KVASIRVGLADWFDSWEQNG---NEGTRQRKTPKL
ELVGGAKYYLEAEHVGIAPSSGVRIGVQIHNTWLNPNVISTYLREKHQIRVHAQRLPEIQ
MLDVSG-RGNFLLTWDFVSSQPISANATAHQXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXL-QAASCDGDLTSGTEPFCGRFSLRQPRHLVLTPPAAQKGYRLDQYTHLCFAYKGDMD
NILKM---------------------------------XQFTCTDLWETCVRPSGCLQPP
LASSSVLVHQIDLFPLA---LELGVFFVDEIIITDTDLTVSQADSGRARPGGNLVESLSV
VGSPPVYNVSFWLAGCGMELPLIRARPLPDEGTEG---------GSKLVEVTTQRLQKTS
PPLGGHFRIQLSN-TVIPGVPVDISAGDLRMLLQNNADDFTSRYLNVSDLNVKEDLSSCY
EHVWTLSWSTQIGDLPNFIR---VSNENLTGVNPAATTRVLYDGGVFLGPIFGDMLVTAH
QHPQVVVRVNEVPARCSGSCSFQYLQASTPRVHSAWCSLDGDI---NLLVYIIGTGFSGD
SQALQLTVNQTSCKVIFSNQTYVVCQMDLLPVGVHRISMLVIPSGLAISASG-EGLFLNV
EPRMDA-VEPSTAAEIGGLWATIRGFGLEDVSLVLFGSQACAINVTTSNSQRIQCKVPPR
GEDG-PVVNVTVIRGEHPWILPAA FAYVSSLN PVIVSLSRNRSNIA--GGEILLIGMTL-
-LVNYTDLDVEVHIRDTLAWVYAQTAQGLEVELPPLPAGLHPISVFINGVSICSQGVDLH
IQYI TQVFDIRPCCGSLLXXXILSISGVGLSREPALGWVFVGNRSCGIVNSTEASIWCET
PSAPLLPD-ADALA--APTPVEVWIGNITFTHGPSPSQAKKGFT FIYEAAATPVVTAVQG
EITNSSLRLYVEGMNISNSVMLLGSLNCDLETQAL------------RSIVNMSGCSFPL
HNLEAGIYPLHVRHKQMGFANMSVALQQFVVT PRIIAIFPTQGSVCGGTVLTVKGV-ALN
SRRGSVQVDLS--GPFTCVILSLDDQTVFCQVTLVGDPLPG-----ASFAL----NVTVL
VNGLTSE CLGNCTLFLWEETT PVLDALTTNLRGSLTTMLIRGQRLGTTADELMTFVDDHL
PCEVTFFNAS-HMACWISDLTPGLHHMSVFHKRNGYACSGNVSRH FNIS PQVFHYFPKNF
SIHGGSVLIIEGTALRGHNTTLVFVGQQACLTVNV-SAELTQCIVPAGNGSVALEMQIDG
LLYHGV--AYSKAXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
XXXXXXXXXXXXXXXEYRVRGHDRVRGWASSVLVFTSRAAITAVTQNFG-YLRGRLVHVF
GTGFSPGNISAAVCGHPCHVLDNATVSAFSCLVLPLDVSLAFLCDLKHEEEGCEASSHTY
VQCDLTFTMGTEKLSKSWPYLYICEESSQCLFVPDRWTV---PAFST-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITAKITEIRKRWGQNTQGNISFQFCRRWSRDH
SWFPEGMPQDGDNVTVESGQFLLLDTNTSIL-NFLHIKGGKLIFMDVEPIELAHSILXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPVPEIIVTHL
RAAAHAHDTVLALEDAVDWYPGDEVVVISGTGVQGARPLEEIVIVETVHNADLHLRTALR
YSHDFTESWVTGEHLVLKATVALLSRSITIQGNFTNERMRHLASCKEANASEGNLKHCLY
SKSEKMLGSRDLGARVIIQSFPEEPSRVQLKGVQFRDLGQAFHKHLSSLTLVGA--MSDS
YIQGCSVWNSF-SRGLSMSGTSGLKVDSNVFYNILGHALLVGIYMEISYT-----SWDTV
PGRKN--DWSEQGNIIRNNVIISVSGTEGLSSSEMLSPSGIYIRNPTTVIEXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX-X-X
XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXELCMTA
G--TPKKWELMISNT-ILNFDLTDCVAI-SCSGCSRGQGGFTVKTRQL--EFPNSSNIVA
FPFPHAAILEDLDGSLSGKNRSHVLASMETLSASCLVNASFGRIVHGSVCAEGVLFHRMS
IGLVNVPDVAYDLTMTDSRNKTTTVNYVGDTLSNIYGWMALLLDQETYTLRFE-TPWIN-
RSLQYSATFDNFAPGNHLLLVHSD-LLSYS---HILIRCGSQLGRALSSLPSPGRDRGCD
WFFNSQLKQLTYLVSGEGQVQVTLQVQEGV-PPTISASTSASESTLKWSLPETWQGVEES
WGG--HNHTIPGPGDDVLILPNKTVLVDTDLPFLKGLYVMGTLEFPVDRSNVLSVACMVI
AGGELKV--GTLDNPLEKEQKLLIFLRASEGVFCDRINGVRIDPGAIXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXIIVKDAVDWRPRDKIILSSSSYEPHEAEVLTVKEIKGHHVRIH
ERLKHRHIGSVHRTEDGRYIPLAAEVGLLTRNIQIQPDISCKGRLLVGSFRKSSQEEFSG
VLQLLN---VEXXXXXSSLYSSIEFTNVPRRAGIVSSTLHQNR-GGIHASASHGLILKDN
IVFGTAGSGIDLEGQAYSLTGNLVVLVTQPVWSTSWVAGIRVNQAKDISLHGNVVAGSER
LGFHIQGHRCAPSEAFWSDNVAHSSLHGLHLYKEDEFDNCTCITGFLAFKNFDYGAMLHV
QNSVQIENFTLVDNTIGLLAVVYVSSVSKSSIDNIQIVLRKSHIVATSSSFDCIEDRVKP
CSANSTSTDRPPSNPRGGRVGILWPGFTSEPHLWPQEPWHKV-KNGHSIPGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGILHPITAERTRMLKIKDRNKFYFHPLQP-XXXXXX
XXXXXXXXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXX--XXXXXXXXXXXX
QSLIQGYICQQTDHVVLVLDSSDAIWVMRKLYPVVSVTGGFVDTFSGVNTPTPCTTSEPV
STFYSILPTNQITKVCFVDQTPQILRLFLLGNKNTSKLLLAVFYHELQSPHVFIGENFIP
PTPIQSAPSLLNETFGANHFNIMDNLLYVVLQGEEPIEIHSGVSIHLALTVMFSVLTESW
KTVILHKLTDFLQVGQDQIRIIYEMPGNERILKTIADDRAKRKRNCPTVACASQ-YRRFG
QRRPLMMEMSS-DRIPPPTSVEILSKVMVIEIGDMPTVRSTGLILPLSNNKLQNLAYKVI
TAHQIGVLENVLNMTIGALLV-THSKADIG---YGXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXNRRVEFLGTPLEPWAISASLEGASDSVLK--GCT-QAETQ
DGYVSFSNLAVLISGSNWHFIFTVTSPP-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXTKTEEISESQTNDHKS----H-IHGSSRH------
QGSQIE-TEKEHPVMGEDLRMKIMLG-KL-SQLPHQ-SSNGVSRRKVCRHTIQEDD----
-RSQEEAAAAAPSMAGVTSHGR-TCAPGSPAQQIYLQETGTWKAAQEQLLRYQLAG--QN
QLLM-LCPDLRQERQRLQ-GQSRLSKKSGSLGLSQEKKSSCGTTEALCLRSTHLETVQEQ
L-------------------------

-------MTAWLISLMGVEALLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGVL
YPNNGSQLEIHLVNTNMVAPALPSIPCDVFPVF--LDLPVVTCRTRSLL--SEAHEGLYS
LEAYFGGQLVSSPSPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMVRKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRH--VSPRKIECTTRAPGKDTRLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
GGL-EVSNSDGDLTSGTEPFCGRFSLRQPQHLVVTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWS----LTRTSPNSWQFRCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLVPLV---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLATTQRQQRTS
PPLGGHFRIQLPN-TVISEVPVQISAHHLHQLLQNNADDFTSRYLNASDFSVKEDLYTCY
ERVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMHVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKMNCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-HVVNVTVIRGNHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAR-
-LVNYTDLDVEVHIQDALALVHTQSAWGLEVALPALPAGLHRISVSINGISIHSQGVDLH
IHYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNQSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRSFARGPSPSLVGNGFTFMYEAAATPVVTAMQG
EITNSSLSLRVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSVPL
HSLEAGIYPLQVRQKQMGFANMSVVPQQFAVTPRIMAIFPSQGSACGGTILTVRGL-LLN
SRTRSVRVDLS--GPFTCEILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGITSECH GNCTLFIREEASP VMDALSTNTSGSLTTVLIRGERLGTTADEPMVFVDDQL
LCNVTFLNAS-HIVCQTRDLAPGPHYLSVFYTRNGYACSDN VSRHFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIRCIVPTGNGSAALEIEVD G
LWYHIGVIGYSNAFTPELISISQSDG-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKHEEDSCEAARHTY
VQCDLTVAVGTERMLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFVSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVIVENGQSLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDTVLALEDAVDWHPGDEVVIISGTGVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIIQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLTMVGA--MRES
FIQGCTVRSSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGITLFQSFTVWESA
GGAQI-FRSGNLRLKNF QVYSCSDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFINSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLASAPEVSYDLTMTDSRNKTTTVNYVRDTLSNLHGWMALLLDQETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILWVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYS
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVRGHHVRIH
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDISCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSEGSWIISSTLHQSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHKCS-CGLLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHI
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
LSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSIFPKTEAEWTASFFN--AGTYREEQKCTY
RFLMQGFVCKQTDQVVLILDGADATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDETPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSSVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFLREIPGHEETLKAIADSRAKRKRNCPTVSCASH-YRRVS
QRRPLMMEMNS-YRSLPPTTVETMSKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENILNMTIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYVLSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSQSFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKC------
RESQ-G-PKKEDTVVAEDMRMKVMLG-KL-NQCPHQ-LMNGVSRRKVNR-----HI----
-IREEEAAVPAPGTTGITSHGH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL--LPGLRQERQQLP-GQSWLSKQSGRLGLSQEKKASCGATEAFCLHSVHLEAIQEQ
L-------------------------

-------MTAWLISLMGVQALLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---SGVL
YPNNGSQLEIHLVNTNMVAPALPSIPCDVFPVF--LDLPVVTCRTRSLL--SEAHEGLYS
LEAYFREQLVSSPSPGSRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKDARLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKERQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
GGA-VPGFTHSDCLFHH--ECSTL-LYSPRHMLGKDPPGLGTRA----------------
----------------L-TGEDCKCSLRAQFHSTLFFSWQFRCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLVPLV---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLATTQRQQRPS
PPLGGHFRIQLPN-TVISEVPVQISAHHLHQLLQNNADDFTSRYLNASDFSVKEDLYTCY
ERVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKMNCKVSFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-HVVNVTVIRGNHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAR-
-LVNYTDLDVEVHIQDALALVHTQSAWGLEVALPALPAGLHRISVSINGISIHSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRSFAHGPSPSLVGNGFTFMYEAAATPVVTAMQG
EITNSSLSLRVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSVPL
HSLEAGIYPLQVRQKQMGFANMSAVPQQFAVTPRIMAIFPSQGSACGGTILTVRGL-LLN
SRTRSVRVDLS--GPFTCEILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGITSECH GNCTLFIREEASPVMDT LSTNTSGSLTTVLIRGERLGTTADEPMVFVDDQL
LCNVTFFNAS-HVVCQTRDLAPGPHYLSVFYTRNGYACSG NVSRHFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIRCIVPTGNGSAALEIEVD G
PRYHIGVIGYSNAFTPELISISQSDG-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKHEEDSCEAARHTY
VQCDLTVAVGTERMLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFVSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQSLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDTVLALEDAVDWHPGDEVVIISGTGVEGAKPMEEIVTVETVQDTDVYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIIQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRSSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYIRSPTNVIEGNRVWGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGITLFQSFTVWESA
GGAQI-FRSSNLRLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCFQGQGGFTVKTSQL--KFINSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLANAPEVSYDLTMTDSRNKTTTVNYVRDTLSNPHGWMALLLDQETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILWVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNSLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYS
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSN VSEGSWIISSTLHQSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
IGFHIRGHKCS-CGLLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHI
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSIIVATSSSFDCIQDKVKP
LSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSIFPKTEAEWTTSFFN--AGTYREEQKCTY
RFLMQGFVCKQTDQVVLILDGADATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSSVSINLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFLREIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVS
QRRPLMMEMNS-YRSSPPTTVETMSKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENILNMTIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYVLSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK-----------
-----------------------------GVNFTARSQSFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKC------
RESQ-G-PKKEDTVVAEDMRMKVMLG-RL-NQCPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHEH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL-------QERQQLP-GQSWLSKQSGSLGLSQEKKASCGATEAFCLHSVHLEAIQEQ
L-------------------------

-------------------------PCICLHIEPEEGSLAGGTWITVIFDGLK---KGIL
YPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXX--XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXFSKAQTPIVYQVNPPSGVPGKLIHIYGLIITGKLET
FDFDVDYIDSPLILEA---------QGDKWVTPCSLVNRQTESCYPIQEDHGLGTLQCRV
EGDY-IGSQNVSFSVFNKGK-SMVHRS-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITVMGDFFDSSAQVTIAGIPD--RHV--SPRKMKCTTRAPGKGTRLSPPQTGNR
GLLFEVGEASEGLELNGTISGYRWQVVPNASSPFGFWSKEGQPFXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXV-KVASIEVGITDWFDSWEQNG---NEKTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVSTYLREKHQIQARAQRRPEIQ
MLTVSG-RGNFFLTWYNVSSQPVPANATAHQIQTAIEDLLAVKCKLEPLSANILLQLGFE
HGL-ESSSSDGDLTSGTEPFCGRFSLRQPRHLVLIPPATQKGYQLDQFTHXXXXXXXXXX
XXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXWQFTCTDLLETCVRHSRDLQIA
LANSPVLVHRIDLLLPA---QETDPLYVDEVIIADMNVTXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXX
XXXXXXXXXXXXX-XXXXXVPVHISASHLHKLLQNNADDFTSRYLNASDFTVKEDLSSCY
EHVWTLSWSTQIGDLPNFIR---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXVVVRVNDIPAHCPGSCSFQYLQESTPRVHSVWYSLDGET---NLLVYITGSGFSSD
SQSFQITVNTTNCKIIFSNQTNVVCQMDLLPVGVHQLSILMRPSGLAVN VTG-EGLFLNV
E PRLDA-VEPSRAADIGGLWVTIQGSGLEDVSLVLFGSQSCAINVTTSNSQRIRCRVPPR
GKDG-HIVNVTVISEDYSGVLPRAFT YDSSLN PMIVSLSRNRSNIA--GGETLFIGMEQ-
-LVNYTDLAVEVHIQDTLAWVHALTAQGLEVLLPPQPAGLHRISVSINGFSICSQGVDLH
IQYI TQVFSIEPCCGSLLGGTVLSISGIGFSRDLASVWVLLGNQSCVVMNVTEESILCET
PPAPGT----EALP--VSVPVEVWAGNGTSTHWPLPSLVGKGFTFRYEAATTPVVTALQG
EIMNSSLRLYVEGSNLSNAAILLGGLSCKLETWSF------------QSNASLSWCSFSL
LSL-SGIYPLQVHQKQMGFANMSMVPSQFGVTPL-LAIFPTNGSACGGXXXXXXGL-VFH
SRRRSVWLHLS--GPKNCLSLHKKKNTILCQVNPIGDPWPG-----ASFTL----NVTVL
VNGLASECQGTCTLFIQEETTPVLDALTINISGSLTTVLLRGQRLGTTENELMVFVDDQL
PCNVTFFNAS-YLACWISDLTPGIHYLSVSHTRNGYACSSNVSRH FYVK PHVFDYFPKNF
SLHGGSLLTIEGTALRGKNTTSVYVGRQACLTVNI-SAEFIQCVVPAGNDSVALEIEVDG
LLYHMGVIGYSNAFTPELLSISQSED-ILTFAVAQISGAVNVDIFIGTSPCVGVSG----
NLTVLRCAVPSLPMGEHQIRGYDHKRGWASSTLAFTARVTVMAVTENFD-CLGGRLVHVS
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVQPLDVSLAFLCGLKHEEDSCESASHTY
VQCDLTVAVGTERLPESWPYLYICEESSQCHFVPDHRTE---SAFPS-LSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITAKITEIRKSWDQNTQGNFSFQFCRRWSRAY
SWFSGRLPRDGDNVTVENGQLLLLDTNTT---------RGKLIFMGPGPLALRAHSILVS
DGGELRIGSANEPFQGKAQIKLYGSSHSTAFFPYGVKFLAVRNGTLSLHGLLPEXXXXXX
XXXXXXXXXXXXXXDAVDWHSGDEVVIVSGTSVEGAKAMEEVVIVETVHEADLYLRSPLR
YSHNFTEDWVTGEHRILKAMVVLLSRNITIQGNLTDERMKFLASCQEVNVSEGNLQHCLC
SKSEKVLGSRDMGARVIIQSFAEEQSQVQLKGVQFRDLGQAYQKHLSSLTLVGA--MKGS
YIQDCTVWNSF-SRGLSMCRTLGLKVDSNVFYNILGHALLVGTYTEIRNI-----TWEVI
TGREN--DWSEQGNLIRNNVTIGVSGHEGLSSPEMLTPSGIYIRSPTNVLEGNRVCMAAY
GYFFHLVTSQTSKAPLLSFTQNMAHSCTRCGLFVYPAFQPPWNNSTGPTLFQNFVVSGSA
GGAQI-FRSSNLHLKNFQVYSCRDFGIDILESDGNTSVTDSLLLGHFHK----GNLCMSA
GIKTPKRQGLMLSNTTFVHFDLFNCVAIRTCSGCSQGQGGFTVKTNQL--KFINTPNLVA
FPFPHAAVLEDMDGSLSGKNGNHIIAFMETLSASCLVNASFSQIVRGSVCGEGVLFHRMS
IGLVNPPDAAYDLTMTDSKNKTITVNYVCNTLSNPYGWMALLLDQETYSLQFE-NPWVN-
RSLQXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX-XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXSGEGQVQVILQVNEGV-SPTISASTSVPESALKWSLPDTWQGVEEG
WGG--YNHTIPGPGDDILILPNKTILVDTDLPFLNGLYVMGTLEFPVDRSNVLSVACMVI
IGGELKV--GTLENPLEKEQKLLILLRTSEGVFCNRYNGIHIDPGTIGIYGKMQLHSAYT
KKSWTHLAADIASRNEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXSTLHQSCGG--HAAASPGIILNNN
IIYRTAGHGIDLEGQAYSLTNNLVVLVTQSMSSPLWVAGIKVNQVKDINLHGNVVAGSER
LGFHLRGHRCFSPEVFWSDNVAHSSLHGLHLYKESGLDNCTSISGFLAFKNFDYGAMLHV
KNSVEIENITLVDNAIGLLAVVYVSSAPQSSIKNVQVVLRNSVLVATSSSFDCIQDRMKP
YSANFTSTYRAPSNPRGGRVGVLWPVFTSEPNQWPQEPWHKV-KNSLSTSGIIKLQ-DVT
FSSFVKSCYSDDLDVCILPNVENTGIMHPITAERTTMLKIKDKNKFYFPPSQP-RKDLQS
VACPETDCESPKKYLFKDLDGRTLGLSAPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
RSLMHGFICKQTDQVVLVLDSADVMDATQKFYPVVSVTNGFVDIFSSVNANTPCSTSKSV
STFYSILPTRKITKICFVDQTPQVLRFFLLGNKNTSKLLLAVFYHELQSPRIFLRGKFIP
PTLVQSVTSLLDESVGANYFNIMDNLMYVVLQGEENIEIRSGVSMHLALSVKFSVLEKGW
KIIILERLTDFLQIDQNQIRLIHEMPGNEGTLKVIADNKAKRKRNCPVVTCASH-YRRVG
QRRPLMMEMGS-HKVIPPTTVETISRVIVIEIGDLPTVRSSGLIPFLSSNKLQNLAHHVI
TAQQTGVLENILNMTIGALMV-TQSKGIMG---YGNTSSFKTENLIYIQPHSLSVLVQPS
NGEVGKELPVQPHLIFLDKQXXXXXXXXXXXXXXXXXXXXXXX-XXXXX--XXSTEAETQ
NGYVSFSDLAVLISGSNWRFIFTVTSPP-GANFTARSRPFAVLPVT-KEKSTIILAASLC
SGVSWLALSCLVCCWFKKHKS--RKMKPEEISESQTNDQKN----H-IHASSKR------
RISQ-K-TEKDDTMMGEDMKRKVILG-KL-SQHPHQ-PLNGVSRRKVSRRTVGE------
----EEAAGSTPSITSITSHGP-SCMPGSLAQQVNLQETGDWKETQEQLLRYQLAG--QG
QMLM-LCPDLKPQKQQLQ-GG--LCKDSGGLGRSQEKTAPCGATEAFCLHSVHPGTTQEQ
L-------------------------

-------MTIWLISLTSIQVLLLAVPYLSLRIEPGEGSLAGGTWITVILDGLG---LGVL
YPTDGSQMEIHLVNMNVAMPALPSIPCDVFPVF--LDLPVVTCRTRSLP--SGAHEGLYS
LEVYFGGQAVGSPSSGAQDSCTFKFSKAQTPVVYQVHPSSGVPGELIHVHGWIITGKLET
FDVDAEYIDSPLILEA---------QEDKWVTPCSLVNRQTGSRYPIQEDRGLGTLQCCV
EGNY-IGSQNVSFSVFNKGK-SMVDKS-AWLISAKQE----LFLYQTHSEVLSVLPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRRV--SPRKIECTTRAPGKDARLTAPQAGNR
GLLFEVGDAAEGLALTEATPGYRWQIVPNASSPSGFWSKAGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHLSGSEEPRTKV-KVASIGVGSADWFDSWEQHG---GEGMWQQKTPKL
ELLGGAKYYLEAEHHGIAPSTGMRIGVQIHNTWLSPDVVTTYLREKHQIRARAQRLPEIQ
VLNVSG-SGNFFLMWDNVSSQPIPANATAHQIQTTIEELLAVKCKLEPPSANVLLRLGFE
QGP-EVSSSDGDLTSGSEPFCGRFSLRQPRHLVLMPSASQKGYWLDQHTHLCLAYKGHTN
MIVKMTVSYTTSFHNVTQKNVTCDWTL----TMTSPERWRFTCTDLWETCVRHSRDVQPP
REDSPVRVHQIDLLPLA---QETGLLFVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
EGSPPVYSVASWLAGCGMELPLISACSVATEGTEE---------GSGLDQVTTQRLQRTS
PPLGGHFHIQLSN-TVILDVPVHISASHLHKLLQSNADAVTSRYLNASDFTVKEDLNTCY
EHVWTLSWSTQIGDLPNFIR---VSAGNLTGLNPVATTRVVYDGGVFLGPVFGDMLATAN
QCTQVVVQVNDIPAHCPGSCSFQYLQASTPWVHSMWYSLDADA---NLLVYIIGTGFSSD
SKSLQVTVNRTNCRVIFSNQTNVVCQTEMLPVGEHWISMLV RPFGLAINASG-EGLFLKV
E PRLDA-VEPSRAAEIGGLWATIRGSSLEGVRLVFFGSQSCAINVTTSGSQRIQCRVPPM
GKDG-RIVNVTVISGDHSAVLPRAFTYVSSLNPAIVTLSRNRSNVA--GGETLLIGMTS-
-LVNCTDLAVEVYVGGALAGVRAQMAWGVEVVLPALPSGLHGISVSINGVSIRSQGVDLY
IQYITEVFSIQPCCGSLLGGTFLSISGIGFGRNPASVWVLVGNQSCDIVNVTEVSIHCKT
PPAPQMPD-ADASA--VSAPVEVWVG NMSFTHGSSASLVGKGFTFMYEAAATPVVTSLQG
EITNSSLRLYVGGSNLSNSVVLLGSLTCDLETQSS------------QSSVNLFGCSFPL
PGLEAGIYPFQVYQKQMGLANTSAVPQQFVMT PWIMAVSPTHGSACGGTVLTVRGL-ALN
SKRRSVQVDLS--GPFTCVVLSVGDHTVLCKVSPVGGPLPG-----VSFSL----DVTVL
VNDVTSECQGNCTLFMQEETTPVVDAMTTNISGSLTTVLIRAQRLGTTASELMVFVDDQL
PCNVTFFNES-YVACQISDLIPGPHYLSVFQARNGYACFGNISRRFYVIPQVFHYFPKHF
SIYGGSLLAIEGTALRGKNTTSVSIGQQACLAVDI-SAELIQCVVPAGNGSVALEIEVD G
LLFHIGIIDYSHDFTPELLSFSQSDD-ILTFAVAQISGATNMDIFIGMSPCVSVSG----
NHTVLQCTVPCLPAGEYRVRGYDHIRGWASSILVFTSRVIITAVTKNFG-YLSGGLVHVF
GTGFSPGKLSAAVCGAPCRILANATVSAFSCLVLPLDVLMAFLCGLKHEEDNCEGTSCTY
VQCDLTVAVGTETLPESWPYLYICEESAQCLFAPDHWTE---SAFPFSFSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITAKITEIRKSWGQNTQGNFSFQFCQRWSKA H
SWFPERVPQDGDNVTVQRGQLLLLDTNTSIL-NLLHVKGGKLIFLAPGPIELRAHAILVS
DGGELRIGSEDKPFQGKAWIKLYGSFYSTRFFPYGIKFLAVRNGTLSLHGSLPEVIVTHL
RVAAHAQDTVLALEDAVDWQPGDEVVIISGTAVEGVKPMEEIVIVETVHNTDLYLRSPLR
YSYNFTENLVAGEHLSLKVTVALLSRSITIQGNLTKERMELLASCQEASASEGNWKRCLY
SMSEKMLGSRDLGASVIIQSFPEEPSLVQLKGVQFQDLGQAFQKHLSSLTLVGT--LRDS
YVQGCTVRNSF-SRGLGICRTVGLKVDSNIFYNILGHALLVGTFMEIRHI-----SWEAI
PGRKK--DWSEVGNIVRNNVIIGVSGAEGLSNPEMLTPSGIYIRNPTNIIEGNRVCAAGF
GYFFHLVTRQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNGTSPTLFQNFTVWESL
GGAQI-VRSSNLHLKNFQVYSCRDFGIDILESDANTSVTDSLLLGHFAHKKSQEGLCMSA
GIKTPQRWELMVSNTAFVNFDLINCVAIRTCSGCSQGQGGFTVKTNQL--KFTNSPNLVA
FPFPHAAILEDLDGSLSGENTSHILPSMETLLASCLVNASFSQIVPGSVCGGGARFHRMS
IGLAHAADTPYDLTITDSRNKTTTVNYVHDTLSNPHGWMALLLDQETYSLRFQ-NPWIN-
RSLQYSATFDNFAPGNSLLLVHTD-LPPSP---NILIRCGSHVGLSLPFLPSPGQNQGCD
WFFKTQLRQLTYLVAGEGQVQVIVQVTEGA-SPTISASTSAPESALKWSLSETWQGVEEG
WGG--YNHSIPGPGDDVLILSNRTVLVDTDLPFLRGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLDGIRIDPGTIGVYGKVQLNGAYP
KKSWTRLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEILTVKEAQGHHIRIY
ERLKHRHIGSAHVMDDGRQIRLAAEVGLLTRNIQIQPDISCRGRVLVGSFRNSNREEFSG
VLQLLN---VEMQNFGSPSYSSIEFTSVSAESWVTSSTLHQSCGGGIHAVASHGIRLNDN
VVFGTAGHGMDLEGQAYSLTNNLVVLVIQPAWSSVWVAGIKMNHAKDIDLRGNVVAGSER
LGFHIRGHQCPSSEVLWSDNVAHSSLHGLHLYEESGLGNCTGISGFLAFKNFDYGAMLRV
EDRMEIENITLVDNGVGLLAVVYVSPASQSSMENMQIVLRSSVIVATSSSFDCIQDRVKP
HSANVTSADRAPSNPRGGRVGILWPVFTSEPNQWPQRPWHEV-RNDRSVSGIMKLQ-DVT
FTGFVKSCHSDDLDVCFLPNIESTGIMPPITAERTRMLKMKDKNKFYFPLLQP-RKDLER
DVCAESNCENPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTGSFFN--TGTFREEQKCTY
RSLVHGYICKQTDHVVLVLDNADAMWTIQKLYPVVSVTGGFVDTFSGVNANTSCSIFRSG
STFYSILPTRQITKVCFADRTPQVLRFFLLGNESTSKLLLAIFYHELQSPRVFLRESFIP
PSLAQSTSSLLNESIGVNYFNVMDNLLYVVLQGGEPIEIRSGISIHLALTVTFSVLGKDW
ERMILERLTSFLQIGQHQIRFVQEMLGNEDTLKAIADSTAKRKRNCPSVTCASH-YRRVG
QRRPLMMEMPS-YGVPPPTTMEPISKVIVIEIGDLPTVSSTVMIPSLSSNKLQNLAHQVI
TAQQTGELGSILNVTIGAILV-TQPKGVLG---NGNTSSFTSGNLVYIRPYALSILVQPS
DGEVGKELPVQPQLVFLDEQNRRVESLGSPSEPWTVSASLEGTSDSVLQ--GSTCIAELH
FGYWSFLYSAKLIRAENKNFTFALISQT-GANFTARSRPFAVLPVTRREKSTVILAVSVS
SAVSWLALSCLLCCWFKKNKS-HRKTKPEEISESQTNDQKD----H-IHITSKC------
RGSRVR-TEKEEPVVREDVKMEVVLG-K-----PHQ-SRNGVSRRKVSRHSIPE------
-----VAAVPAPSVTGTLSQGH-TCAPGSPAWQTKLQETGNWKEAQEQLLRYQRAG--HG
QLLL-LYPDLRQDRQKQP-EQSPLSKESGSSRLSQEKNATCGGAEAFCLRSVHPEAMQEQ
L-------------------------

-------MNLWRTFLLSAGLVFLTGTASGSFVKPQEGSIAGGTWITITLDAIAEGLF-LS
NRTSASQLEVSLVN-----PDLPRLPCDVSPLH--LDLPTIRCRTR-----SSPQEGLYY
VEVIFKGHVINNLTEVEKENYSFKFSAEQTPVVYQINPSSGTPGNLIQIHGKTIAGRYET
LDFNVDYIDGPAVLTS---------E-DGWTSLCSFVDRRAGSTYPIEAKDGLGTLQCRV
EGNH-IGSHNVSFSVFNKGK-SAVHKD-AWLISAKQE----LFLYQTHPEIFSVVPAAGS
LAGGTDLTVTGDFFEEPVQVTAAGVPCKVKYV--SPQEIRCTTEPLGKGRTPGAPQPGNR
GLLFEVWDDA--SDLTEAGPGYRWQFVPNASSPVRFLSGAEKSFSSRLRGFFVAPETNNY
TFWIQADGQASLYLSLSQDPKQKV-RIASLPAGNSEWADNWVNNW----SELWQPKSQKF
ELTAGSRYYLEALHHAQTPSTGMRVGVQIHNTWLDPRVLSSYRTERHEIRARALHLPEVQ
MLTVSG-TGYFSISWNNTL-RMIPTNATAHQVQAAIEELLSVGCETEPTSAKILFHHGFE
KEDMKNIITTGHIVSGTEPFCGRFSVHRPSQLVKTSPSTLPRYDLTKYSRVCFAHKGHLS
NILHLSVSYTNVSSCPVRRNLTCQWDF----NETDSKSWRFTCTNLWKKCVNLSVPLQDL
PANSPVFVDQIDLQSPVLQKETPGSFYLDELIIADRAVIVSQRDPKPPRPGGRIIEAVSV
EGSPPTYNVSWRISGCGASLPLLSPRGAVLGEGSQEHGHLQVSTEDVRVSLSIQRLQKSS
PPLGGTFHIHLGS-TVIPDVSVHISGPQLRRLLQDNVDNFTAPFFNTSDFTVTRDSSSCH
ESVWTLTWEKTAGDLPNVISVQ-VSSENLTGLKPSVSTRVVYDGGVFIGPIFGDMLATLH
NQTQVVVTVNDVLANCSGSCSFQFSQELTPIVRDVEYSSGDGP---QAAVALRGAGFGEQ
QQ---VLVGSRRCRVAGASGSQVLCRVPRLRAGLHAVTLRVAPHGLALGGTAARGIFLTV
QPALAA-VEPPSTAEIGGLRVTLRGTGLEGVNAVLFGSQPCPILEEGRNSTRIQCKVPSR
GTED-AAVDVTLISGNQSTRVTNLFQYDPSLNPALVSLSRNRSGIA--GGEELHIGISH-
-FASYQGSDVKVQIGDSWPQIQAQTERGVNVTLPALPAGCYNISVLINGIAVAPNRVEPL
IQYLSEIFSIEPCCGSVLGGTLLTISGMGFSQNPALVSVSMDNQTCTVTHLEEETIWCLT
PPAVNLSN-EDPRD--ISVRVNVAI SSGSLQHAL---FANRTTTFNYQRALTPLVTAVET
EVTDGSLLLSIQGINISGSLAKLGHSECQLEFQHG------------NQSAMSYQCSLPM
NSLEPGTVPIQVIQRQLGYARVAARQQALTIT PQITSISPSQGSICGGMLLTISGI-ALK
SRRNLVEVSLE--SNYSCEIQKSDNDSITCVVLPGAHPLHPQWLAVASRAL----SVTVV
VNGVSSVCLGDCTLHLHEHWTPLVHLVTWRTNGTATYVTIKGQRLAWQGGSPVVHVDNST
ACTVTFWNET-IIRCHTGCLAPGEHHVSIASRKSGRACFRGTSSLLSLLPWVYQFYPRNF
STHGGGLLSLAGLALKGQRMTSVLVDHHPCFILSI-TCVLIQCTVPPGKGSRALSLKVDG
HSYY LGTISYSEEFTPAFLSLVSTG-LLLNFNVSQVTETDFIHVFIGDFPCSNTTI----
TGSVLQCTAPLLPVGEYPVLGLDIPRGWASSNLTFTSHLAVTAARHNWS-GLKGGQVYLH
GTGFSPGKTLVTVCGTSCEVLGNMTVTELSCLAPRLRASLAILCGLTHSSASCQEDRATF
IGCDIRVMVGTSQQRGAVPYFYVCGDTRPQGHFAGLLAS--ISSPPPSFPPAFLNPKVER
DEVLIYNSSCNITMETEAEMECEGANQPITAKITEIWKNWGQNTQGNLALQLCGRWEED S
SWAAGHPPRDGDNVTIEGGRTLLLGTATSIL-HLLQLKGGKLLFTGPGPVELHAHYILVS
DGGELQVGSPEAPFQHKAHIYLYGSLHSPPLFPYGVKFLAVRNGTLSIHGWMPKVVFTHL
KSSANAGDTRLVLQESVDWQPGDEIL-VGSSGLGDAQQQEEVAFIQSLSNTELHLRSPLR
YPHSAGEGWGNGQGLPSRAVVALISRRVVVQGNVTLERMSHLRQCADADIPMPGGSGCLY
KRSERQLGSRDLGAILVVEAFQGQASRLRLEGVQFRHVGQAFRHHRSALTAAGNTWLPDS
YIHGCCVLDSF-GQGLHLTGISNLSVDRNVFYNISGHGILLAICTFFFSFFP----FFPI
FSFKG--KGLEEENKISNNIVIGLSVTDGFSNIETLSPAGIYVRAPASHIRGNTVWGAGY
GYFFHLSPEGPSKVPLLSFSENTAHSCTRQGLLVYPEYLPDS-----RVQFNNFTAWSCH
GGAQI-FSSRNLELQHFWISACKDFGIDIVESLGNISVSDSVLNGHLGQK---DSTCMSA
GLKTPKRYQLLISNTAFRNFDVNTCTAIRTCSGCYPGQGGFTVTAEHL--TFTNSPFQVS
FPFPHSAILEDLDGSTTGQRGSHVLPSTDILPAPCTASANFSQASGGSVCDSDLVFHRMD
LHLKEAPDIPYNLTVTDSRNKTNTVNYVPDTLSNLYGWMVLLLDKETYTLTFD-SPLVS-
KQLQYSVTFSNFKAGNYLLVEHKD-LPAHL---EAVVSCGTRRGQPLQLLPSYGHHRGCD
WHLDSKLGKFTYLVTGADLIQVTLKEKE--T--VALPTPAPSCAVMKWSLAETWNGVGKG
WGG--SSGSIPGPGEDVIILPNRTILVDVALPPLRGLYILGTLEFPSSSSNALSAACVLV
LGGVLRV--GSSEHPLERDLKLLFLLRASEGIYCDRLEDINVHPGSIGVYGQVQIYSAYP
KMPWTHLGTDVAPGNERILVEDEVDWDQGGDAVISSSSYEAHQAEVVTLKEVHGHNIRIH
EHLLHRHIGRPHDTENGRKIPLAAEVGLLTRNVRIQSDVACAGRMLVGHFTDSSGKEFEG
SWDSPVLIKQKTLVFAQERGAEMCIHLIKVKTSSLSASVKHEHH----------------
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-------MTGWLISLMSIEVLLLAVPHLTLRIEPKEGSLAGGTWITVIFDGLE---TSVL
YPTNGSQLKIRLVNM--VVPALPSVPCDVFPVF--LQLPVVKCQTRSLL--SETHEGLYS
LEVHSEGQVLDNPSPVSKDSCTFKFSKAQTPIVYHVNPSSGVPGNLIHVHGWIFTGKLET
FDFDTEYIDSPLVLES---------QRDRWVTPCSLVNRQTGSCYPIQEDHGLGTLQCRV
EGDY-IGSQNVSFSVFNKGK-SMVHKN-AWLISAKQD----LFLYQTHSEILSVFPETGS
IGGRTDVTITGDFFDNSAQVTIAGIPCDVRHV--SSRKIECTTRPPGKGARLTPPQAGNR
GLLFEVADAAEGLELTETTPGYRWQIVPNASSPIRFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTQV-KVASIRAGTADWFDSWEQNG---DEGAWQQKTPKL
KLLSGVQYYLEAEHVGISPSKGMRIGVQIHNTWLNPDVVNTYLREKHQIRARAQRLPEIQ
MLNVSG-RGTFFLTWDNVSSQPIPANATAHQIQTTLEELLAVKCKLEPHSANILLRLGFE
QGL-EGYSSDGDPTTGTEPFCGRFSLRQPQHLVLTPPAPQKSFRLDQYTHLCIAYKGHTS
NILKMTVFFTLGLQNIV-KNTTCDWSL----PGINPNSWQFTCENLWETCVHQFGDLQAH
LANPPVLILQINLLPLA---PEKGLLYVDEVIIADTNLTVSQEDSGIARPGGHLVESVSV
TGSPPVYNIS-LLAGCATELPLITACSVPTNGTEE---------GAELVQGTTQRLQRTS
PPLGGHFRIHLPN-AVIPDVPVHISANYLQKLLQNNADNFTSRYLNVSDFTVKEDLNSCY
EHIWTLSWSTQIGDLPNFIR---VSDEDLTGLDPVATTRVVYDGGVFLGPIFGDMLATAN
QHPQVVVLVNDIPAHCPGNCSFQYLQESTPCMHSVWYSLDGDI---NLLVYISGTGFSGD
SKSLQVTVNETSCKVVFSNQTNVVCQTDLLPVGVHQISMLV RPCGLAVSASG-EGLFLNV
E PRLDA-VEPSRAAEIGGIWATIRGSSLEGVSMVLFGSQSCAINVSASNSRRIECKVPSR
GNDG-HTVNVTVISGDYYAVLHSGFTFVPSLNPVILSLSRNQSSIA--GGEALFIRMTQ-
-LVNYTDLDMQVHIQDALAEIHAQTAQGLEVVLPALPTGLYGVSVSINGVNICSQGVDLH
IQYITDVYSIQPCCGSLMGGTILSILGTGFSRDPASVWVLVGNRSCDVVNVTEVSVWCET
SPAPVRPD-ANAL S--VPAPVEVWAGSTSFTRGPSPQLVGKGFTFIYEAASTPVVTTMWG
EITNDSLMLYVQGNNLSDAVILLGSLTCELETHSP------------GSRMNLSGCSFPL
LSLEAGIYPLQVRQKQVGLADMSAVPQQFVVT PQITTISPTQGSACGGTVLTVRGV-AFH
SRKRSVQVDLS--GPFTCAILSLGDHAIVCQVTLIGDPLPG-----ASFSL----NVTVL
VNGLRSACQGNCTVFMWEETTPTVDTLATNTSGSLTTVVMRGQRLGTAADELLVFVDDQL
PCNVTFFNAS-RVACQIGDLTPGRHYLSVFHARSGYTCFGNISRYFHVMPQVIHYYPKNF
SIYGGGLLAIEGTALRGQNTTFVYVGQQACRMVTI-NAELICCTVPAGNGSATLELEVDG
LLYHV GAVGYSTAFTPELLSLSQTDD-MVTFAVGRISGALNVDIFIGTSPCVGVSG----
NHTILQCTAPLLPAGQYQVTGYDHTRGWASSVLVFTSTVRISAVTENFG-CLDGRLVHVF
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDVSLAFLCDLKPEEDSCEAASLTY
VRCDLTVAVGMERAPESWPYLYICAESFQSRLVPDHWTE---SAFPT-WSGLFISPKVER
DEVLIYNSSCNITMETEAKMECETPNQPITAKITEIRKSWGQNTQGNFSFQFCRRWSRA H
SWYPERVPQDGDNVTVESGQVLLLDTNTSIL-NLLHVKGGKLVFMDLGPIELRAHAILVS
DGGELLIGSEAEPFQSRAQIKLYGSSYSSTFFPYGVKFLAVRNGTLSLHGLLPEVLVTHL
RAAAQAQDTVLALEDAVDWHPGDEVVIISRAGVEGAKPMEEIVVVETVHNTDLHLRSPLR
YSHSFPENWEAGGYHVLKATVALLSRNIIIQGNLTTERKRLLASCQEINASEGNLQNCLY
SKSEKILGSRDLGAKVIIQSFKEEPSCVQLKGVQFRDMGQTFRRHLSSLTVVGA--VKDS
YIQGCTVWRSF-SRGLSLDSTWGLKVDNNVFYNILGHALLVGTYINIRPI-----SWEAI
PGRKY--DWSEKGNMIRNNVIIRLSGAEGLSSSEMMTPSGIYVCSPTNVIEGNRVCAAGY
GYFFHLVTKRTSQAPLLSFSQNVAHSCTRCGLFVYPEFQPPWDNGSGPTLFQNFTVWGSA
GGVQI-FRSSNLHLKNLQVYECRDFGIDILESDANTSVTDSLLVGHFTHK---GSLCMSS
GIKTPKRWELMISNTTFANFDRISCVAIRTCSGCSQGQGKLFEQIGPMANKANNQQNMVS
ITFYHDAAVSVL-GSVFYRSRDHISLAQNLIIGKCLISQSFFSLPPLSLCNSDIYFHFIN
QPRADAPDVSYNLTLTDSRNKSTTVNYVVDTLSNLHGWMALLLDQETYSLRFE-NPWIH-
SSLQYSATFDNFAHGNYLLLVHTD-VPPYP---DILIRCGSQVGRSLLSLPSPGQDQSCD
WFFSSQLRQLTYLVSGKGQIQVILQVREGM-PPTIAASTSVPESALRWSNPETWQDIEEG
WGG--HNHSVPGPGDDVLILPNRTVLVDTDLPALKGLYVLGTLEFPVDRSNVLSVACMVI
AGGELKVETGTLENPLQKEQKLTILLRASEGVFCDRFNGIQIDPGIIGVYGKVQLHSAYT
KKSWTHLGADIASGNERIIIEDAVDWKPHDKIVLSSTSYEPHEAEVLTVKEVKGYHVGIH
ERLKHRHIGSVHVIEDGRHISLAAEVGLLTRNIQIRPDTSCRGRLLVG-FRKSDREEFSG
VLQLLN---VEIQNFGTPLYSSIEFNNVSSGSWIMSSTVHQSCGGGIHAAASHGIILKDN
IVFGAAGHGIDLEGQAYSLTNNLVILVTQSALSTVWVAGIKVNQAKEIDLHGNVVAGSER
LGFHIRGHRCSSPEVLWSDNVAHSNLHGLHLYKEIGLDNCTSISGFLAFKNFDYGAMLHV
ENSMEIENITLVDNAIGLFVVVYVSFVPQSSRQDVQIVLRDSDIVATSSSFDCIQDRVKP
QTANMTFRDRAPSNPRGGRVGILWPAFTSQPNQWPQEPWHKV-RNGYSISGIMKLQADVT
FSSFGKSCYSDDLDICILPNVQNTGIMHPITAERTRMLNMKDKNKFYFPPLHL-RKDLER
VICMESGCENPRKYLFKDLDGNTLNLPAPVSVFPKIEAEWTGSFFN--TGTFREKKKCTY
QPLMQGFICKQTDQVVLILDNADVTWAIQKLYPVVSVTNGFVDTFSHINANPPCSTFRSV
STFYSILPTGKITKVCFMDQTPEVLQFFLLGNKSTSKLLLAVFYYELQSPHVFLRETFIP
PTLGKSASSLLEESIGTNYFNIMDNFLYVVLQGEEPIEIRSGVSLHLAFTVTFSVVENGW
EIVILERLTDFLHLHQNQIRIVHTMPGNEGTLKAIADSRAKRKRNCPTVACASY-YSRVG
QRKPLMMEMSSSHKVSPPPTMETVSTVIVIEIGDLPSVKNTGLISSLSSNKLQNLAHQLI
IAQQTGVLKNVLNITTGALLV-TQPKGIIG---SGNTSSFKTGNLIYIQPCALSVLVQPS
DGEVGKELPVQPQLVFLDEQNRRVESLGPPSEPWTVLVSLEGTSDSVLK--GYT-LAETQ
DGYVSFSNLAVLISGSNWHFIFTVTSPP-GVNFTARSRQFAVLPVTEKESSTIILSASLC
SVASWLALICLVCCWFKKKK--NRKTKPEEISESQANDPKN----H-IQVSSKR------
QGSHVD-TVKEDIVMGEGMRIIHMLG-KL-NQLAHQ-SLNGVSRRKVGR-----PT----
-AGQETTAVPVPSVTGITSHRH-SCSPSSPAQQVYMQESGNWKEAQEQLLRYQLAR--QN
QLLL-LCPDLKEGRQQLQ-GQSQLGKEGGSLGPSQETKTACDASVAVHLHSAHPDPMPEQ
L-------------------------

------VMPAWLIALLSMKVLLLADPYLSFQIEPSEGSLAGGTWITVIFNGLE---KSIL
YPSNGSQLEIVLVNV--AVSTLPRIPCDVHPVF--VDLPVVTCQTRSLL--SEDHAGLYS
LEIRSGEQLLSGRCPGSLDSCAFKFSKAQTPVVYHVNPSSGVPGEVVHVYGWIITDQLET
FDPDVDYIDSPLILEA---------GRDKRLTPCSLVNRQTGNCFPIQEENGLGTVQCRV
EGDY-IGSQNVSFSVFNKGR-SMVHKD-AWLISAKQD----LFLYQTYSEIISVFPKVGS
LGGRTDITITGDFFDLSAQVTIAGIPCDIRHV--SPRKIDCTTRAPGRGARLTAPQAGNR
GLLFEVGDAAEGMELTEATPGYRWQVVPNASSPSGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSPASLRFSFSEEPRTKV-EVASVGVGTADWFDSWEQNG---NEGSWQQKTAKL
ELRGGAKYYLEAEQHGIAPRRGMRIGVQIHNTWLNPDVVNTYLLEKHQIRARAQRLPEIQ
MLNVSA-GGSFFLTWDNVSSQPVPTNATAQQIQTSIEELLMVKCNLEPVSAHILLRLGFE
QGL-EGSSSDGVLTSSTEPFCGRFSLGQLQHLILNPSADKNGYQLHQYPYLCSAYRGHIN
RTMTMTVSFIFDFQNIT-KNATCDWSL----AEPHPESWQFNCINLWDTCVRRSEDLQSS
PANTPLLVHWIDIHPVA---PEAGLLYLDEIILADANVTVSQADAGTARPGGNLVESVSV
TGFPPVYSVAFWLVGCGSELPLITACYVPAEGTGE---------GSELIEVTAQRLQGTS
PPLGGHFFLQLSD-TVIPDVPVHMSSRQLHKLLQDNADESTSGYLNVSDFTVTKELNSCY
EHVWTLSWTTQIGDLPNFIS---ASDKNLTGVNPAVAVRVVYDGGVFLGPIFGDMLATAN
QKSQVTVQVNDVPAHCSGSCSFQYLQESTPSVDDVWYSPGYDA---NLLVYFTGTGLPRD
SQSLQVTVNRTSCEVIFSNETRAVCEMDLLPVGVYQVSMLVN PSGLAVNASG-EGLFLKV
E PRLDA-VEPATAAEIGGLWVTIRGSSLEGVSLVLFGTQSCAIDVIISNSQQIQCKVPPR
GNDG-YTVNVTVTSGEHSTVLPRAFTYVSSLNPVIVSLSRNRSSLA--GGEILFLGMAR-
-LANYTDLFVQVCVQDTSAQVLAQTAWGLEVVLPPLLAGIHTISVFINGVSIRSQGVDLH
IQYLTEVLSVEPHSGSLLGGTILSLSGIGLGRDPALIWVFVDSQPCGVVNLTDVDIWCET
PPAVLPPG-ADVLT--VPASVEIWVGNSSFLHGA--VLVGKGLTFMYEAATTPVVTAMWG
ELTNNSLGFYVQGRNLSDSAILLGTMKCDLEVQSL------------VDNVSLSVCSFPL
CSLEAGVYSLQVRHKWMGFANMSAMPQKYELSPQIMAIFPTHGSVCGGTVLTVRGV-AFS
TRRGSVHVDLS--GPFACMILSLADHTVLCQTKLVDSHFPE-----VSFAL----NVTVL
VNGLASKCEGNC TLFVQEETTPV VDALTTSINGSLTTLLMRGQRLGTTDAEPTVFVDDQL
PCRIIFFNTS-HVACQMSDLTPGLHYLSVVHTSN GYACLDSVYRSFFIVP QVFDYFPKDF
STHGGSLLIIKGTALRGWNATSVYIGQQACVTVNV-SSELIQCIVPAGDGSVALEIEVD G
VLYHLGLVGYSSVFTPELLSVSRSHD-ILTFTVAQISGAANVDILIGMSPCAGVSG----
NSTILQCMVPLLPAGEYPVTGYDHNRGWASSALILELRARVTSVTENY-GCLGEKILHVF
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLNVSLAFLCDLKRAEDSCEVSSHTY
LQCDLTVAMGTERLPGSWPYLYLCDESSQCLLAPDR-RE---PAFPS-FSGLFLSPKVER
DEVLIYNSSCNITMETEAEMECGTPNQPIIAKITEIQKSRGQNTQGNFPFQFCRRWSRPH
S WFPQRVPHDGDNVTVETSQLLLLDVNTSLL-NSLHIKGGKLIFMEPGPIELRAHSILIT
HGGELRIGSQDKPFQGKAQVKLYGSSHSPPFFPYGVKFLAVKNGTLSLHGSVPEVTVTYL
RAAARAGDTVLVLEESVDWHPGDEAVIVGGMGVEGAGPMEEVVVVETVHNADLHIRTPLR
YSYNFTGNWVAGKNHILKATVALLSRNIVIQGNLTLERLKLLHSCREANAAGGNLKHCLY
SKSEKMLGARDLGARVIIQSFPEEPSFVKLHGVQFRDLGQAFNKHQSSLTLVGT--MIGS
YIQSCSVWGSF-SRGLSMHRTWGLRVDSNIFYKILGHALLVGTYMDRKFT-----TSETI
IGGKN--DWWTQGSTIRNNVIISISGAEGLSSPEMLAPSGIYTLSPTNVIEGNRVCAAGY
GYVFHLMTSQTSQAPLFSFKLNTAHSCTRYGLLIYPKFQPLWNNDTGLTVFQDFMVWGSA
GGVQI-FRSNNLHLKNFQVYACRDCGIDILESDTNTLVTDSFLLGHFTHE---GSLCMSA
GIKTPKRWELLVSNTTFVNFD-LNCVAIRTCSGCSQGQGGFTVKTREL--KFENSTNLVA
FPFPHAAILEDLDGSLSGKKGSHILPSVETLSDTCLANTSFSHIVPGSICGEGVLFHRMS
IGLDKALDVPKNLIVTDSRNKTITVNYVRDTLSNYYGWMALLLDQETYSLQFL-NRWMD-
RSLQYSATFDSFASRNHLLLLHRD-LPPHP---DILIRCGSRVGQSLPSPPLPSHNRGCD
WFFNSQSGELTYLVSGEGQVQVFLQVKEGV-PPTVSASTSVPESALKWSLPETWQDVAKG
WGG--YNQTIPGPGDDVLILPNRTVLVDTDLPALRRLYVMGTLEFPVDRSNVLSVACLLV
AGGELKV--GSLKNPLEKEQRLLVLLRASEEIFCDHFDEIRVDPGTIGVFGKLNLHSAYP
KKSWVH LGADIAPGNERIIVDSVVDWQPHDKIVLSSSSYEPHEAEVLTVKEVKGHHIKVY
ERLRHRHIGSAHIMENGRHIPLAAEVGLLTRNIKIQSDSSCRGRLFVGSFRKSSREELSG
VLQLLN---VEIQNLGSPLYSSIEFTGMS AGSWIIASTVHQSCGVGIHASASHGMILNDN
VVFGTSGHGIDLEGQNYSLTNNLVILTMHSSRSSPWVAGIKVNYAKDIILHGNVVAGSER
LGFHICGHGCSS-ELLWSDNVVHSSLHGLHLYKKHEPTNCTGVSGFLAFKNFDYGAMVQT
ENSVVLQNITLVDNTIGLLAVAYVSSAPLSSIRAVQIVLRNSVIVATSTSFDCIQDRKTP
QSANWTSTDRAPSNPRGGRIGILWPVFTSERNQWPQEPWHKL-RSGHAVSGIMKLQ-DVT
FSSFVKSCYSGDLDVCILPNEYNTGIMYPITAERTRMLRMKDKNKFFFPPSQP-RKDLEG
TTCLESDWESSRKYLFTDLDGRTLGLPPPVSVFPKIEAEWTGSFFN--TGIFREEQKCTF
RAMIQGFFCKQTDHVVLILHNIDVTQTFPKLYPLVSVTNGFVDTFSRVKDNTLCSTPTSV
STFYSIFPTRQITKVCFVEQPPPSLHIFLLGNRSFSKLILAVFYDEIQSPHVFLEKRFIP
PTPVKSAPSLLDESAGANYFDIMNNLLYVVLQGEEPVEIHSSASINLAFTVRFSVLEKDW
KRVILERLTCFLQIDPNQIKFTLEMPGNEETLEAIANSRGKRKRNCPTVTCGGADAGRFG
QRRPLRAEMTS-YRITPTTSVETLSKVIVIEVGDLPNTGSTEFIPSFPSNRLQNLARQVI
TAQQTGVLENILGMTVGALLV-TKSEGVSG---YRNASSLRTGNLIYTRPSVLSVLVQPS
DGEVGIDLPVQPQLVFLDEKNQRVESLGLPSEPWVISASLEGAPDSMLK--GCT-LAETR
DGYVSFSRLTVLISGSNWHFVFTVISPP-GANFTARSKAFAVLPVARKERSTIILALSLC
SLVSWLALSCLVCCWFKKSKN--RKIKPEDMSESQTKDQKK----N-THISSKH------
RGLRVK-AAKEETLTGEDMRMKVIQG-RQ-NQFPLQ-STDGVSKRNVSRRAVPE------
----DRAATPAPRIPKTTSQGL-TCVPGALAQKLTLQEPGNWKEAQKQLLRYQLAG--HN
QLLL-LCPDLRQERQQGQ-ESSQLNKESDCMGLSPEK-GTCVPSETVCLHTAPSETIQ--
--------------------------

-------MPGWLISLMTIEVLLLSVPHLSLWIEPEEGSLAGGTWITVTFDGLD---SGIL
YPTNGSQLEISLVNV--AVPAWPSVPCDVSPVF--LDVPVVMCQTRSLL--SEAHEGLYS
LEVRSGGQVVGSPDLGPQDSCTFKFSKAQTPLIYQVNPPSGVPGKLIHVYGWIITGRLET
FDVDAEYIDSPLVLEA---------QGEKWVTPCSLINKQTGSHYPLQEDHGLGTLTCRV
EGHY-IGSQNISFSVFNKGK-SMVNKS-AWVISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNFAQVTIAGIPCDISHV--SPRKIECTTRAPGRGMRLTAPQAGNR
GLLFEVGDAAEGLELTEATPGYRRKIVPNASSSFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLYFSWSEEQRTKV-KVASIQVGTTDWFDSWEQNG---NEGTWQQKTPKL
ELVGGAKYYLEAEHHGIAPSKGMRIGIQIHNTWLNPDVVTTYLREKHQISVRAQRLPEIQ
MLNVSG-RGDFFLTWDNVSSQPIPANATAHQIQTTIENLLAVKCKLEPLSANILLRLGFE
QGL-EGSRSDGDLTSGTEPFCGRFSLHQPRHLDLILPATQKGYRLDQYSHLCMAYKGHRN
MILRMTVSFVIGFQNITKKNSTCDWSL----TGTSPKSWKFTCTDLWDMCVHRSGDLQLP
QANAPVLVHQIALHSLA---QETGLLCVDEIIIADTNLTVSQDDSATARPGGSLVESVSV
VGSHPVYNVVSWMTGCGMELPLIAARSVPTEGT-E---------DSGLVQVTTQRLQKTS
PPLGGHFRIQLSN-TVIPDVPVHISAGHLYKLFQDNADDFTSRYLSVSDFTVKEDLISCY
EHGWTLSWSTQVGDLPNFIE---VSDQNLTGMNPSVAIRVVYDGGVFLGPIFGDMLAVAH
QHTQVVVRVNDIPAQCLGSCSFQYLSGSTPRVHSVWYSLDGET---NLLVYITGTGFSGD
SQSLQVVVNKTSCKVSFSNQSTVVCQIDLLPVGVHQVSVLVR PSGLAVNGSG-EGLLLYV
E PRLDA-VEPSQAAEIGGLWATIRGSSLEDVSLVLFGSQSCAISVTTRNSHRIQCKVPPR
EKDG-YTVNVTVFSRDHSAVLPRAFTYVSSLNPVIVSLSRNRSNIA--GGETLFIGMAL-
-LGNYTDLDVEIHVQDTLIQVHAQTAQGLQVVLPPLPAGLHSLSVSINGISIHSQGVVLH
IWYITEVFSIEPCCGSLLGGTILSISGVGFSRNSALVWVHVGNQPCDIVDSREMSIRCET
LPAPMLSS-VDS----LPFPVVVWSG NMSFLHGPAPSLVGKGFTFTYESAATPVVSAMWG
EITNSSLRFYVEGNNLSNSVILLGSWKCDLETQSF------------GGNMSLSGCAFPL
HDLEAGIYPLQVRHKHMGFANMSAVPQHFAVN PWITSIFPMHSSACGGTVLTVRGT-TLK
SRRKSVRVDFS--GPFTCIILSLSDDTVICQINLVGDHLAG-----ASFML----NVTVL
VNGLASKCQGDCTVFMQEEATPVVDTLTAGINGSVVTILMRGQRLGSTTDEPKVFVDNKL
PCNLTFFNAS-HVACYINGLTPGLHYLSDVHTSNGCACWGNVSRHFSIKPQVFYFYPKNF
SIHGGSLLAIEGAALRGQNTTSVYVGQQACLTINI-SSELIQCIVPAGNGSVSLEIEV DR
ILYHIGVIDYSDGFTPELISVSQIDD-ILTFTVIQISGAANMDIFIGTSPCAGVSG----
NHTVVQCTAPLLPAGEYHVRGYDHSRGWASSALVFTVRVTITTVTENFG-CLGGRLVHVL
GAGFSPGTVSAAVCGTPCQVLANATVSAFSCLVLPLDVSLAFLCGLKSEEDSCEATVHTY
VQCDLTVTVGTQRLAESWPYLYMCEEGSQCVLMPDPWTE---PAFPS-FSGLFVSPKVER
DEVLIYNSSCTITMETEAEMECETPNQPITTKITEIRKSWGQNTQGNYSLQFCLRWSRTH
S WFPNRQPQDGDNVTVEKGQVLLLDRNTSIL-NLLHIKGGKLVFMGPGPIELRAHAILVS
DGGELRIGSEDKPFQGKAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPAVTVTYL
RTASCAEDKVLALEDAVDWHPGDEVVIVSGTGVEGVSLLEEIVTVETVQHADLHLRSPLR
YSHNWTESWVAGEHRILKATVALLSRSITIKGNLTHERRKLLASCQETNVPEGNLQHCLY
SKSEKVLGSRDLGARVIIQSFPKEPSWVQLKGVQFQDMGQTFRKHLSSITLVGA--MRGS
YIRGCTVWSSF-SRGLDLGRTWGLEVDSNVIYKILGHALLVGTYMEISYI-----PWEFI
PGRKH--GWSEQGNIVRNNVIINVSGAEGLSSPEMLTPSGIYISSPNNVIEENRVCASGY
GYFFHLVTSQTSQAPLLSFTQNVAHFCVRFGLFVYPKFQPSWDHNTGPTLFQNFRVWGSA
GGVQI-FRSSNLHLKNFQVYSCRDFGIDILESDANTSVTDSLLLGHFSHE-LQERLCMSA
GIKTPKRWELMISNTTFVNFDLIDCVAIRTCSGCSQGQGGFTVKTNHL--KFTNSPNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCSLNANYSQIVAGSVCGEGVLFHRMS
VGLPNAPDVSCDLTITDSRNRTTTVNYVHDTLSNHYGWMALLLDQETYSLRFA-DPCIN-
RSLQYSATFDNFSPGNYLLLVHTD-LPSYP---HILVRCGSRVGWSLLSLPSPGQDQGCD
WFFNRQSKQLTYLVSGEDQVQVTVQVEEGVVPPTIAASTSAPKSTLKWSFPETWKDVEEG
WGG--YNHTIPGPGDDVLILPNKTVLVDTDLPFLKGLYVMGTLEFPVNRSNILSVACLVI
AGGELKV--GTLENPLEKEQKLVILLRASEGIFCDHFNGIRIDPGTIGVYGKFQLHSAYP
KKSWTH LGANIAPGNERIIVEDAVDWKPLDKIVLSSSSYEPHEAEVLTVKEVKGHHIRVH
ERLQHQHIGSPHVMEDGKRIHLAAEVGLLTRNIQIKPDTSCSGTLLVGSFTKSPREEFSG
VLQFLN---VEIQNFGSPLYSSIEFT NVSSGSWILSSTLHQSCGGGIHASASHGIILNEN
VVFGTAGHGIDLEGEAHSLTNNLVVLMTQSAWSTTWVAGIKVNQAKDILLHGNIVAGSER
LGFHIQGQRCSS-DMFWSDNVAHSNLHGLHLYKKSGPDNCTSVSGFLAFKNFDYGAMIQI
ENSVEIENITLVDNSVGLLAVVYVSSALQHSIKNVQIVLRNSVIVATSSSFDCILDRMEP
HSANLTSTDRAPPNPKGGRVGILWPVFTSVQNQWPRDPWHKI-RNGHSVSGIMKLQ-DVT
FSSFVKSCYSDDLDICILPNPESTGMVHPIIAERTRMLKMRDKNKFYFPPLHP-RKDLER
VICPESDCESPRKYLFKDLDGTALRLPPPVSVFPNTEAEWTGSFFN--TGTFREEQKCTY
RPLIPGFICKQTDQVVLTLDTVGGPWAIQKLYPVVSVTSGFVDTFSGINDNTLCSTSESV
STFYSILPTRQITKVCFVDQTPQILRFILIGNKSTSKILLAVFYHELQSPHVFLRGSFIP
PTLVQSASSLLDESVGANYFSIMDNLLYVVLQGEEPIEIRTDVSLHLAFTMTFSVLEKGW
EVVILEKVTNFLQIEQNQIRFTHEMSGNERTLKAIADSKAKRRHNCPTVTCASH-YRRVG
QRRPLMMEMSS-YRIFPPTTMETISKVIAFEIGDLPISKRTGLNPSLSSNKLQSLAHQII
TAQQTGVLENVLNMTIGALLV-TQSKGVIG---YGNTSSFKVENLIYVQPYALFVLVQPS
DGEVGKELSVQPQLVFLDRQNQRVESLGSPSEPWTISVSLEGALDSVLR--GCT-QAKTQ
DGYVSFSNLAVLISGSNWNFIFTVISPP-GANFTARSKSFAVLPETGKERSTVILAASLC
SVVSWLALSCLVCCWFNRSK--HRKTKPEEISESQAKDEKK----Q-IHVSSKR------
RASQIE-IEEEDSRKAEEMRMKVLRG-RL-NQLPHQ-TLDGVSRRKLGHR----CA----
-APAEESTVPAPSTASLTSQGY-TSALGSPARQAHPPETKNWNMAQ------ELAG--PN
QLLL-LGPDLGQDRQQWQ-GQSQQSEERGSLGLSQEKNTL--------------------
--------------------------

-------MTAWLISLMSIEVLLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---LGVL
YPNNGSQLEIHLVNVNMVVPALRSVPCDVFPVF--LDLPVVTCRTRSVL--SEAHEGLYF
LEAYFGGQLVSSPNPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCRV
EGDY-IGSQNVSFSVFNKGK-SMVHKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKDVRLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSQEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKVEPLWSNILLRLGFE
RGP-EISNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWSL----TRTSPESWQFHCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLLPLA---QETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEE---------GSGLVLVTTQRRQRTS
PPLGGHFRIQLPN-TVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDLYTCY
EHVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATAN
QHTQVVVRVNDVPAHCPGSCSFRYLQGSTPCVHSVWYSVDGDI---NLMIYITGTGFSGD
SQFLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDM-VEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPR
GKDG-RIVNVTVIRGDYSAVLPRAFT YVSSLN PVIVTLSRNISNIA--GGETLVIGVAR-
-LMNYTDLDVEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIRSQGVDLH
IQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVFVGNRSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQG
EITNSSLSLHVGGSNLSNSVILLGNLNCDVETQSF------------QGNVSLSGCSIPL
HSLEAGIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGL-LLN
SRRRSVRVDLS--GPFTCVILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGLTSE CQGNCTLFIREEASP VMDALSTNTSGSLTTVLIRGQRLATTADEPMVFVDDQL
PCNVTFFNAS-HVVCQTRDLAPGPHYLSVFYTRNGYACSG NVSRHFYIMPQVFH YFPKNF
SLHGGSLLTIEGTGLRGQNTTSVYIDQQACLTVNI-GAELIRCIVPTGNGSVALEIEVDG
LWYYVGVIGYNNA FTPELISISQSDD-ILTFAVAQISGAANIDIFVGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKREEDSCEAARHTY
VQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVTVENGQLLLLDTNTSIL-NLLHIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHALDTVLALEDAVDWHPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLY
SMSEKMLGSRDIGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSLTLVGA--MRES
FIQGCTVRNSF-SR GLSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKD--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAGY
GYFFHLMTDQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWESA
GGAQI-FRSSNLRLKNF KVYSCRDFGIDVLESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQL--KFTNSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMS
IGLANTPEVSYDLTMTDSRNKTTTVNYVRDTLSNPHGWMALLLDQETYSLQSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGQVQVILRVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTIPGPGDDVLILPDRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEEEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVQLYSAYP
KNSWTHLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIY
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSAGSWIISSTLHQSCGGGIHAAANHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSER
LGFHIRGHKCSSCELLWSDNVVHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHV
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSVIVATSSSFDCIQDKVKP
HSANLTSTDRAPSNPRGGRIGILWPVFTSEQNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENSGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFN--AGTFREEQKCTY
QFLMQGFICKQTDQVVLILDSTDAIWAIQKLYPVVSVTSGFVDVFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLALTVMVSVLEKGW
EIVILERLTNFLQIGQNQIRFIHEMPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVG
QRRPLMMEMNS-HRASPPMTVETISKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENVLNMTIGALLV-TQSKGVIG---YGNTSSFKTGNLIYIRPYALSILVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSKPFAVLPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNQNN----H-IHISFKR------
RESQ-G-PKKEDAVVGEDMRMKVMLG-KV-NQCPHQ-LMNGVSRRKVSR-----HI----
-VREEEAAVPAPGTTGITSHGH-ICAPGAPAQQVYLQETGNWKEGQEQLLRYQLTG--QD
QLLL-LCPDFRQERQQLP-GQSRLSKQSGSLGLSQEKKASCGATEAFCLHSVHPETIQEQ
L-------------------------

-------MTAWLISLVGVETLLLAVPHLSLHIEPEEGSLAGGTWITVIFDGLE---LGVL
YPNNGSQLEIHLVNTNMVAPALPSIPCDVFPVF--LDLPVVTCRTRSLL--SEAHEGLYS
LEAYFGGQLVSSPSPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIMTGRLET
FDFDAEYIDSPVILEA---------QGDKWVTPCSLVNRQTGSCYPIQEDHGLGTLQCHV
EGDY-IGSQNVSFSVFNKGK-SMVRKK-AWLISAKQD----LFLYQTHSEILSVFPETGS
LGGRTDITITGDFFDNSAQVTIAGIPCDVRH--VSPRKIECTTRAPGKDTRLTTPQPGNR
GLLFEVGDAVEGLELTEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-KVASISVGTADWFDSWEQNR---DEGTWQQKTPKL
ELLGGAKYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRARAQRLPEVQ
VLNVSG-RGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWANILLRLGFE
GGL-EVSNSDGDLTSGTEPFCGRFSLRQPQHLVVTPPAAQKGYRLDQYTHLCLAYKGHMN
KILKMTVSFTIGFQNMV-KNTTCDWS----LTRTSPNSWQFRCTDLWETCVRCSGDLQPP
PANSPVLVHQIDLVPLV---QETDLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSV
VGSPPVYSVTSWLAGCGTELPLITARSILTEGSPE---------NLISILVC--------
--------VVLSL-MTKPKVPVQISAHHLHQLLQNNADDFTSRYLNASDFSVKEDLYTCY
ERVWTLSWSTQIGDLPNFIR---VSDENLTGVNPAAAMRVVYDGGVFLGPIFGDMLATAN
QHSQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSVDGDV---NLMIYITGTGFSGD
SQFLQVTVNKMNCKVIFSNQTNVVCQTDLLPVGVHRILMLVR PSGLAISATG-EDLFLNV
E PRLDT-VEPSTAADIGGLWATIRGSSLEGVSLVLFGSYSCAINVTTSNSSRIQCKVPPR
GKDG-HVVNVTVIRGNHSAVLPRAFT YVSSLN PVIVTLSRNTSNIA--GGETLVIGVAR-
-LVNYTDLDVEVHIQDALALVHTQSAWGLEVALPALPAGLHRISVSINGISIHSQGVDLH
IHYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNQSCDIVNLTEASIWCET
LPAPQIPD-AGAPT--VPAAVEVWAGNRSFACGPSPSLVGNGFTFMYEAAATPVVTAMQG
EITNSSLSLRVGGSNLSNSVILLGNLNCDAETQSF------------QGNSSLSGCSVPL
HSLEAGIYPLQVRQKQMGFANMSVVPQQFAVTPRIMAIFPSQGSACGGTILTVRGL-LLN
SRTRSVRVDLS--GPFTCEILSLGDHTILCQVSLEGDPLPG-----ASFSL----NVTVL
VNGITSECH GNCTLFIREEASPIM DALSTNTSGSLTTVLIRGERLGTTADEPMVFVDDQL
LCNVTFLNES-HIVCQTRDLAPGPHYLSVFYTRNGYACSDN VSRHFYIMPQVF HYFPKNF
SIHGGSLLTIEGTGLRGQNTTSVYIDQQACLMVNI-GAELIRCIVPTGNGSAALEIEVD G
LWYHIGVIGYSNAFTPELISISQSDG-ILTFAVAQISGAANIDIFIGMSPCVGVSG----
NHTVLQCVVPSLPAGEYHVRGYDCIRGWASSVLVFTSRVIITAVKENFG-CLGGRLVHVF
GAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKHEEDSCEAARHTY
VQCDLTVAVGTERTLESWPYLYICEESSQCLFVPDHWAE---SMFPS-FSGLFVSPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTH
S WFPERLPQDGDNVIVENGQSLLLDTNTSVL-NLLLIKGGKLIFMAPGPIELRAHAILVS
DGGELRIGSEDKPFQGRAQITLYGSSHSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTR L
RATAHARDTVLALEDAVDWHPGDEVVIISGTGVEGAKPMEEIVTVETVQDTDLYLKSPLR
YSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLLSCQEANAPEGNLQHCLY
SMSEKMLGSRDMGARVIIQSFPEEPSQVQLKGVQFRVLGQAFHKHLSSLTMVGA--MRES
FIQGCTVRSSF-SRG LSMCGTLGLKVDSNVFYNILGHALLVGTCMEMRYI-----SWEAI
HGRKY--DWSGHGNIIRNNVIIRVSGAEGLSNPEMLTPSGIYIRSPANVIEGNRVCGAGY
GYFFHLVTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGITLFQSFTVWESA
GGAQI-FRSSNLRLKNF QVYSCRDFGIDILESDANTSVTDSLLLGHFAHK---GSLCMSS
GIKTPKRWELMVSNTTFVNFDLTNCVAIRTCSDCSRGQGGFTVKTSQL--KFINSSNLVA
FPFPHAAILEDLDGSLSGKNRSHILASMETLSASCLVNASFGRVVHGSACGGGVLFHRMS
IGLASAPEVSYDLTMTDSRNKTTTVNYVRDTLSNIHGWMALLLDQETYSLRSE-NLWIN-
RSLQYSATFDNFAPGNYLLLVHTD-LPPYP---DILLRCGSRVGLSFPFLPSPGQNQGCD
WFFNSQLRQLTYLVSGEGRVRVILWVKEGM-PPTISASTSAPESALKWSLPETWQGVEEG
WGG--YNNTLPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVI
AGGELKV--GTLENPLEKEQKLLILLRASEGVFCDRLNGIHIDPGTIGVYGKVQLYSAYS
KNSWTH LGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIH
ERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDISCRGRLFVGPLRKSSREEFSG
VLQLLN---VEIQNFGSPLYSSVEFSNVSEGSWIISSTLHQSCGGGIHATASHGVLLNDN
IVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQAKDINLHGNVVAGSER
VGFHIRGHKCS-CGLLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHI
ENSVEIENITLVDNTIGLLAVVYVFSAPQNSIKKVQIVLRNSSIVATSSSFDCIQDKVKP
LSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKV-RNDHSISGIMKLQ-DVT
FSSFVKSCYSDDLDVCILPNAENTGIMHPITAERTRMLKIKDKNKFYFPSLQP-RKDLGK
VVCPELDCASPRKYLFKDLDGRALGLPPPVSIFPKTEAEWTASFFN--AGTYREEQKCTY
RFLMQGFVCKQTDQVVLILDGADATWAIQKLYPVVSVTSGFVDIFSSVNANIPCSTSGSV
STFYSILPTRQITKVCFMDETPQVLRFFLLGNKSTSKLLLAVFYHELQNPHVFLGESFIP
PTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSSVSIHLALTVMVSVLEKGW
EIVILKRLTNFLQIGQNQIRFLREIPGHEETLKAIADSRAKRKRNCPTVTCASH-YRRVS
QRRPLMMEMNS-YRSSPPTTVETMSKVIVIEIGDSPTVRSTGMISSLSSNKLQNLAHQVI
TAQQTGVLENILNMTIGALLV-TQSKGVIG---YGNSSSFKTGNLIYIRPYVLSVLVQPS
DGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDSVLK--GCT-QAETQ
DGYVSFYNLAVLISGSNWHFIFTVTSPP-GVNFTARSQSFAVSPVTRKEKSTIILAASLS
SVASWLALSCLVCCWLKRSK--SRKTKPEEIPESQTNNENN----H-IHTSSKC------
RESQ-G-PKKEDTVVAEDMRMKVMLG-RL-NQCPHQ-LMNGVSRRKVNR-----HI----
-IREEEAAVPAPGTTGITSHGH-TCAPGAPAQQVYLQETGNWKEGQEQLLRYQLAG--QD
QLLL-------QERQQLP-GQSWLSKQSGRLGLSQEKKASCGATVAFCLHSVHLEAIQEQ
L-------------------------

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----------------------MVHKE-AWLISAKQE----LFLYQTYPEIHSVFPKVGS
LGGRTDITITGDFFDPSARVTIAGIPCDIRHV--SPRKIECTTRAPGNGARLTAPQAGNR
GLLFEVGNAVKDEELTEATPGYRWQIVPNASSPSGFWSKEGRPFRARLSGFFVAPETNNY
TFWIQADSQAFLRFSSSEEPRMKV-EVASIAVGTADWFDSWEQNG---NEGSWQQKTNKL
ELQGGAKYYLEAEQHGIAPSRGMRIAVQIHNTWLNPDVVNTYLLEKHQIRAQAQRLPEIQ
VLNMSG-KGNFFLTWGNVSSQPVPANATAQQIQTIIEELLVVKCNLVPLSARVLLWLGFE
QGL-DGSRSDGVLTSSTEPFCGRFSLGQLRHLILSPGAVSKGYQLDRYPYLCFAYRGHMN
RTLDMTVSFLFGFQNVM-KNITCDWSL----MEPHPESWHFTCNNLWDTCVRHSEELQSS
LANTPLLVHRIDIFPVV---PEADLLYVDEIILADTNVTVSQADSGVARPGGNVVESVSV
VGVPPVYSIASWMAGCGSELPLITACYVPTQGTGE---------GSELIEVTAKRLQRTS
PPLGGHFSLHLSD-TVIPDVPVHVSARQLHKLLQDNADESTSGYLNADDFIVTKDQNSCY
EHVWTLSWTTQIGDLPNFIR---VSDQNLTGLNPTITARVVYDGGVFLGPILGDTLATAN
QQTQVTVQVNDIPAHCSGSCSFQYQRASTPSVDCVWYSLGSDV---NLLVHFTGNGFPRD
AQFLQVTVINTSCEVIFSNETNVACELALLPVGVHRVFMLVR PSGLALNASG-EGLFLRV
E PRLDA-VEPSTGAEIGGWWVTLRGSSLEGVSLVLFGTRSCVIDVIRSNSQQIQCKVPPR
GKDG-YTVNVTVINGDHSTVLARAFTYVSSLNPVIVSLSRNRSNIA--GGEILFLGMTL-
-MVNYTDLNVQIYIQNTSAQVLAKTAWGLEVLLPPLLPGIYVISAFINGISIRSQGLATH
LGNSTLN-----CLQSE----LIQ--------KRGHVGLLVG-EKGNVWQLFEVGLWWEV
VTREGKPL-VEHFNKTVSEALNKWFIIAP---LP--LYIEIPLDFLKK------------
-FSLS---------DLGSMTAPLPFLHCFFFMSKTTDTCSLSFLLPLQTSLPLCFCSSPW
VDLHI-----------------QYLTEVFS------------MEPCSGSLLVVRFH---S
QNNDLVRSELQGPGKVSCNIF----FDIICTRRTNGKKMKE-----FKFSL----AFTVH
GNGLTSKCEGNCTLFLEEAATPIVDALTISISGSLTTVLMRGQRLGSA-GEPTAFVDGQL
LCHTTFFNTS-YVACQMRDLAPGFHYLSAVRTSAGYACLNSVSRNFFVVPQVFDYFPKDF
SIHGGSLLTIKGTTLRGWKTTFVYVGQQACLTVNI-SSEFIQCIVPAGNGSAALEIDVDG
VLYHMGFVDYSSIFTPELLSVSRSHD-ILTFTVARISGAANVDILIGTSPCLDVAG----
NRTILRCMVPLLPAGEYAVTGYDHSRGWVSSTLILVLRATVTSVTENYEGCLGGRLLHVL
GAGFSPGNISAAVCGAPCQVLANATVSAFSCLVLPLDASLAFLCNLRHAEDSCGVSRPTY
LQCDLTVSVGMERLPGSWPYVYLCEESSQGLFVPDHQ------IFLS-FSGLFLSPKVER
DEVLIYNSSCNITMETEAEMECGTPNQPITAKITEIQKSRGQNTQ---------------
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------VMPGWLISLLSMEILILAEPHLSFHIDPVEGSLAGGTWITVIFNDLE---RSVL
YPTNGSQLEIDLVNM--VLPALPKIPCDVSPVF--LDLPVVTCQTRSLL--SEAQEGLYS
LEVRSGGQIVGSPCQGFQDSCTFKFSKAYTPIVYRVNPSSGVPGEVIHVYGRIITGRLET
FDSDVDYIDSPLVLEA---------EGDRWVTPCSLINRQTGSCFHIQEEHGLGTVQCSV
EGNY-IGSQNVSFSVFNKGK-AMVHKD-AWLISAKQD----LFLYQTHSEILSVFPEVGS
LGGRTDISITGDFFDTSAQVTIAGIPCDIRHV--SPRKIECTTRAPGKGARLTAPQAGNR
GLLFEVGEAAESLALTEVTPGYRWQIVPNASSPSGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQASLHFSWSEEPRTKV-TTASIGVGTTDWFDSWEQQG---NEGNWQQKTPKL
ELLAGSQYYLEAEQYGIAPSKGMRIGVQIHNTWLNPDVVNTYLQEKHQIRAQAQRCPEIQ
MLNVSRSRGNFFLTWDNVSSQPVPVNATAQQIQATIEELLAVKCKLEPLSANILLWLGFE
QGL-EGSSSDGILTGATEPFCGRFSLRQPQNLVLNCSDIQKGYWLDQYPHLCIAYKGLVN
KILNLTVYFTFGSQNVM-KNTTCDWRF----TEADPESWHFACINIWDTCVHHFEDLQSS
LANTPLLVHQIDIVPVV---QDAGLFYVDEIIIADTNITVSQADSGTARPGGNLVESVFV
AGSFPVYNITSWLAGCGLEVPLINACYVPAEGTEE---------ESELIQMTAQRLQNTS
PPLGGHFVIHLSD-TVIPDVSIHVSAGQLHKLLQDNSDKFTSGYLNLSDFTVKEDVNSCY
EHVWTLSWATSIGDLPSFIR---VSDQNLTGMNPVVTTRVVYDGGVFLGPIFGDMLVTAN
QQTQVAVWVNDIPAHCSGSCSFQYLQESTPRVDFVWYSLGSDI---NLLVYFTGTGFSSD
SQSLQVTMNKTNCKVIFSNQTNVACEVDLLPVGVHPILMLVR PSGLAVNASG-EGLFLYV
E PRLDT-VEPSRAAEIGGVWATIRGSSLEDISLVLFGSQACAIDVTTSSSHQIQCKVPPR
GKEG-HTVNVTVIRGNHSTVLSKGFT YVSSLN PVIISLSRNRSSIA--GGEVLFLGMAL-
-LVNYTDLDVQVHMQDTLAQVLSQTARGLEVVLPPLPPGRHTISVTINGISIRSQGV DLH
IQYLTDVF SFEPCCGSFLGGTILSISGIGLGRDPALISVLVGHHPCDIVNLTEVSIWCDT
PPSLLMPS-ADVL I--VPAPVEVWAGNTSLIHGP--SLVGKDLTFMYEAARTPVVTAIWG
EFVNSSLWLYVEGNNISASAILLGSLKCDVEIQSF------------DGNISLLGCAFPL
HNLEAGMYPLQVRHKWMGFANMSAVPQQFEIT PRITTIFPTHGSICGGTVFTMKGF-ALN
SRRGSVQVDLS--GPFTCVILNLGNDTILCQINLLSDYLSE-----HSFAL----NVTVL
VNGLVSECEGNCTLFMQKDTTPFVDALTTNISGSITTLLMGGKRLSTAADEPTVFVDDQL
LCYPTFFNAS-HVTCQISDLTPGLHYLSALRTNTGYACLGNISRHFLIMPHVLDYFPKNF
SIHGGGLLAIKGTALRGQNTTLVYVGQQACLTVSI-SSELLQCIIPAGNGSVALEMEVD G
VLYHIGIVDYSDAFTPELLSISQSHD-ILTFTVAHISGAANVNIFIGTSQCVGVSG----
NRTVLQCMVPLLPAGKYPVTGYDCSRGWASSVLVLTLRAAVTAVTENF-GCLGGQLLHVF
GAGFSPGNVSAAVCGVPCQVLANATVSAFSCLVLPLDVSLAFLCDLRHAEDICEDISHTY
LQCDLTVTVGTERLLESWPYLYLCEESSECHFVPDHWAE---PAFPT-FSGLFLSPKVER
DEVLICNSSCSITMETEAEMECETPNQPITAKITEIQKSWGQNTQEKFSFQFCRRWSRAH
S WFPERLPQDGDNVTVENGHVLLLDVNTSIL-NLLHIKGGKLIFMAPGPLELRAHSILVT
DGGVLQIGSKEKPFQGKAQIKLYGSSHSANFFPYGAKFLAVRNGTLSLHGSVSEVTVTY L
RAAAHAGDTMLALEDVVDWHQGDEVVIISAMGAEGARPMEEVVTVETVHNADLHLRSPLR
YSYNSIEDWVIGENLSLKVTVALLSRSITIQGNLTQERMELLTSCQEADAKEGSLKHCLY
SKSEKVLGSRDLGARIIIQSFPEEPSLVQLKGVEFHNLGQAFRKHLSSITLVGA--MRGS
YLQSCTIWGSF-SR GLSIHGTQGLKVDSNVLYKIMGHALLVGTFTERRYN-----SCETI
AEGKD--GWSEQGNVIRNNVILSVSGAEGLSNSEMLAPCGIYIHSPTNMIEGNRVCGAGY
GYFFHLVTRETSEAPVLSFTHNTAHSCTRYGLLIYPKFKPPWNDHTGPTVIQNFRVWGSA
GGAQI-SRSSNLYLKNF QVYSCRDFGLDILESDANTSVTDSLLVGHFAHK---GSLCMSA
GMKTPKRWELVISNTTFVNFDFINCVAIRTCSGCSQGQGGFTVKTRQL--TFINSTNLVA
FPFPHAAVLEDLDGSLSGKNGSHILASMETLSASCLANRSVSQIVPGSICGERVLFHRMS
IGLMNALGVSKNLTMTDSRNKTTTVNYVCDTLSSHHGWMALLLDQETYTLQFQ-SPWID-
RSLQYSATFDSFAPRNYLLVVHKD-LPPYP---DILIRCGSQVGQALPAHPLPGQDKGCD
WFFNSQLRRLIYMVSGEGQVQVFLQVKEGV-PPKISASTLVPESALKWSLPETWLDVEEG
WGG--YNQTTPGPGDDVLILPNRTVLVDTDLPLLKGLYVMGTLEFPVDRSNVLSVACLLV
AGGQLKV--GTKENPLEKEQRLLILLRASEEVFCDRFDGIRIDPGTIGVYGKVQLHSAYP
KKSWVR LGADIAPGNERIIVEDAVDWQPHDRIILGSSSYEPHEAEILTVKEVKGHHIQIH
ERLKYRHIGSAHVMEDGQHIPLAAEVGVLTRNIQIQPDISCRGRLLVGSFRKSTREEFSG
VLQLLN---VEIQNLGSPLYSSIEFTDVSP GSWIISSTVHQSCGGGIHVFSRHGIILNDN
IVFGTSGHGIDLEGQTYSLTNNLVMLTMQSASSSSWVAGIKVNCAEDINLHGNVVAGSER
LGFHIRGHGCSP-EALWSDNVVHSCLHGIHLYKEREPNNCTGISGFLAFKNFDYGAMVQT
ENSVTMQNITLVDNVIGLLAIVCVSSTLLSSIGNVQIVLKDSVIVATSSSFDCILDRKKP
QSANLTSTDRPPSNPRGGRVGILWPVFTSEPNRWPQEPWHKV-RSGYSVSGIIKLQ-DVT
FAGFEKSCYSDDLDVCILPNEASTGIMYPITAERTRMLKMKDKNKFYFPLSHP-RKGLER
MICPESDCESPRKYLFTDLDGRTLGLPPPVSVFPYMEAEWAGSFFR--SGIFREEQKCIF
RAMIQGFICKQTDQVVLILDNLDVTWAILKSYPVVSVTNGFVDTFSSGTDNGLCSTSSSL
STFYSILPTRQITKVCFVDQTPPFLRFFLLGNSRVSKLVLSIFYHEIQNPHVFLGKSFIP
PTLVQSASSMLNEPAGANYFDIMNNLLYVVLQGEEPVEIHTRVSVHLAFTVTFLVQEKGW
ERVMLESLTSFLQIEQNQVRFTHEMPGNEETLQTIADSGAKRKLNCPTVTCGSP-YRRFG
QRRPLMVEMRS-YRVTPPTTVETMSKVIVIEIGDLPTIRNTGQIPSLPSKKLQNLAHQVI
TAQQTGVLEKVLNMTVGALLV-TQSEGVTG---YKNSSSFKTGNLIYIRPYILSVLVQPS
DGEVGKELPVQPQLVFLDEKNRRVESLGLPSEPWIISASLEGATNSVLK--GCT-QAETH
NGYVSFSGLAVLISGSNWHLAFTVTSPP-GTNFTARSKSFAVLPVTRKERSTIILAMSLC
SVVSWLGLSCLVCCWFKKNKT--RKIKPEDIAESQASDPKK----N-THNPYKQ------
QGLKVE-TEKEDAVMGEDIRMKARQG-RL-NQLPQL-PMNGVSRRKVTRQAVPE------
----EKAAIHAPRIPRVTSQGL-TCAPGSPAQQPTLQETGNWKEAQEQLLRYQLAG--QE
QLLL-LCPDLRQARQQWQ-EPSQLNKGRGCLRLSQEK-GSCAATETFCLHSAPPETI---
--------------------------

-------MTGWLVPLTSIEVLLLAVSSLSIHVEPKEGSLAGGTWLTVIFDDFE---ASLL
YPANGSQLEIHLVN--VAAPALPSVPCDLAPVF--LALPAVMCRTRPLL--SEAHEGLYY
LEVRSGAQVVGSPRPGPQDSGTFKFSRAQTPIVYQVHPPSGVPXXXXXXXXXXXXXXXXX
XXXXXXXXXXPLILEA---------HGDQWVTPCSLVNRKTGRCYPIQEDHGLGTLQCRV
EGNY-IGSQNVSFSVFNRGK-STVHKN-AWLVSAKQD----LFLYQTYSEILSVFPATGS
LGGGTDITITGDFFDNPVRVTIAXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXWEFACTDLRGTCVHDPACLQPP
PANCPVLVHGIDLLPVS---PGTGAFYVDEVIIADTNLTXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXSVPSEGAEG---------GSGSVQATTWRLQRTS
PPLGGHFRIQLSD-TVIPGVPVHISASHLQKLLQNNADDFTSRYLNVSDFTVTEDLKSCY
EHVWTLSWSTQVGDLPNFIR---VSDENLTGVNPVVTTRVVYDGGVFLGPIFGDMLVTAN
EHTQVVVRVNDVPPHCSSSCSFQYLEGSTPRVXXXXXXX-XDI---DLLVYITGSSFSDD
SQALQVTVNQTHCKVISSNQTNVVCRTGLLPVGVHRISVLVRPSGLAISASG-GGLFLNV
EPRLDA-VEPSRAADTGGLWATIRGSGLEDVSLVLFGSQPCAVNVTTSHSRRIQCKVPPR
GKDG-PIVNVTVIRGDHSVVLPTAFIYVSSLNPVITSLSRNRSNVA--XXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDLH
IQYLTEVFSIQPCCGSLLGGTILSLSGVGFSRDPALVWVLVGNRSCDIVNSTETNIWCET
PPAPLLPG--------APAPVEVWAGRRPSPSGPPPS LVGEGFTFMYEAAATPVVTAMRG
EITNHGLRLSVVGRNLSNSVVLLGGLSCDLETQSS------------GTHMILSGCDFPL
PSLEAGIYPLRVRQKHMGFANMSAVPQQFVVT PRITAVFPTRGSACGGTVVTVRGL-VLN
SSRRSVQVDLS--GPFICAMLSLGDQAVICQVALVGDSLPG-----ASFNLNVTLNVTVL
VNGLPSECQGNCTLFLREEMTPVVDALTINSSGSLTMVLIRGRRLSTAADAPVVLVADRL
PCFVTFFNMS-HVTCWIKDLAPGPHYLSVFHARYGYACFGNVSRDFHVLPQVFHYFPKNF
SIHGGSLLTMEGSALKGRNTTLVYVGRQACLMVNL-GSEVFRCMVPAGIGSVALDIKVDG
LSYQMGIMVYSDFTMLS---F--QT-----------------DIYFVIGAARDIYGHWVG
VFCQTQCVRP--SAGRYQVR-YDRTGGWSS--LMFTSRVTVTAVTENFG-CLGGRLVHVF
GAGFSPGNISAAVCGAACQVLANATVSAFSCLVPPLNXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXPKVER
DEVLIYNSSCTITMETEAKMECETCNQPITAKITEIRKSRGQNTQGNFSLXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPEVVVTHL
RAAARAQDTVLALEDAVDWHPGEEVVILSRAGAQGAKPTEETVIVDTVHHADLHLRSPLR
YSHNATENWVAGERRVLNVMVLLLSRSVTIQGNVTDERGKLLASCPGAEASEGNLQDCLY
SKSEKVLGSRDLGARVIIQSFPEEPSQVQLQGVQFRDLGQAFRKHGSSLTLAGA--LRXX
XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXLGHALLVGASPEIRHI-----PWEVI
PGGEN--DWSEQGNVIRNNVIIDVSGAEGLSSPEMLAPSGIYIRDPTNVVEXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXI-FRSSNLHLKNFQVYACRDFGIDVLESDANTSVTDSLLLGHFAHEXXXXXXXXXX
XXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXGFTVKTSQL--KFTNSPNAVA
FPFPHAAVLEDLDGSLTGKNGRHVLASMETLSASCLVSDSFSQLVHGSVCEENVRFHQMS
IGLANAPKLSYDLTITDSGNKTTTVSYVHDTLSNPNGWMALLLDQETYSLRFE-SPWTNN
SSLQYSATFDSFAPGNYLLLVHRD-MWSYP---DILLKCGSRVGRALPSLPSPDQDQGCD
WFFDSQLRQLTYLVSGEGQVQVSLQVREGV-SPTISASTLAPESILKWSLPEAWEGVEEG
WGG--HNGTIPGPGDDVLILPNRTVLVDTDLPWLRGLYVTGTLEFPVDRSNVLSVACMVI
AGGELRV--GTLENPLEKEKKLLILLRASEGVFCDRFNGIRVDPGTIGVFGKVQLHSAYP
KKSWTRLGADIASGNDRIIVEDTVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHIRIH
ERLKHRHIGSVHVMEDGRSVRLAAEVGLLTRNIQIQPDTACGGRLLVGSFRKSSMEEISG
VLQLFN---VEIRNLGSPLYSSIDLTNVSAGSWIISSTLHQSCGGGIRAAASRGIILNDN
LVFGTVGHGIDLEGQDCSLSNNLVVLMTQSAWSTVWVAGIKVNQAKDVHLHGNVVAGSER
LGFHVRGHRCSSPEALWSDNVAHSSLHGLHLYQECGPDNCTSVSGFLAFKNFDYGAMLRV
QNSVEVENITLVDNTVGLWAAVYVSSAPQCYIRNIQIVLRNSVLVATSSSFDCIQDRVKP
RSANVTSADRAPSNPRGGRVGLLWPVFTSEPHQWPRESWHKV-RSGRSISGIIKLQ-DVT
FSSFLKSCYSDDLDVCILPNAENTGIVHPITAERTRMRKIKDKNKFYFPPLQT-RKDLET
LICSEPDCESPRRYLFKDLDGRALGLPPPVSVFPKTEGEWTGSFFN--TGTFREEQKCTY
RPPIQGYICKQTDHVILILESDEATWTTQTFYPVVSVTSGFVDTFSSVNANTACSTSGSV
SSFYSILPTKEITKVCFVDRTPQALRFFLLGNKSTSKLLLAVFYHELQSPRVFLGERFIP
PTLLQSTSSLLNESIGSNYFSIPDNLLYVVLQGEEPVEIRSGVSIHLALTVMFSALEEGW
EIMILERLTDFLQVSQDQIRILHDMPGDEATLKAIADSRAKRKRTCPTVTCASL-D-RVG
QRRPLMMEESS-YRVLPPTTVETLSKVVVIEIGDLPTVQSPGLTPSLSSNKLQSLAHQVI
SAQQTGVLESVLNTTIGALLV-TQSKGVTG---YGNTSSFKPGNLIYVRPSALSVLVQPS
DGEVGKELGVQPELVFLDKQNRRVESLGPPSEPWAVSVSLEGAPDSVLR--GCT-RAETQ
DGYVSFSNLAVLISGSNWHFIFTVTSPP-GVNFTARSRPFAVLAATPSERSTMLLAASLC
SVVSWLALCCLVCCWFKKSKN--RKIKSEEISESQTNDQKN----H-IHVTSKC------
QGPQIE-MEKEGARMAEDLRMKVLRG-RL-NQLPHQ-SLNGVSRRKGSRLVVWEEG----
-GRQAEAAAPAPGVAGVTAHGN-PCAPGSPAQQVYLQETGSWKEAQEQLLRYQLAG--QD
QLLL-LCRDLRQERQRLQ-GQSRLDKDTVSLGLSQEKPASCSTTEAFCLHPVHPEAVQEH
L-------------------------

-------MPIWLSSLISIEVVFLAVPGLCLHIEPEEGSLAGGTWITVIFDDLD---MGLL
YPTNGSQLEINLVN--MAVPALLSIPCDVSPIF--LNLPVVMCQTRTLL--SEVQEGMYL
LEVLSGGQVASSLSPGPQDSCTFKFSKAETPIVYQVYPPSGVPGELIYVYGWIITGRLET
FDIDAMYIDSPLILEA---------QGGKCITPCSLVNRQTGSSYPVEENQGLGTLQCRV
EGNY-IGSQNVSFSVFNKGR-SVIHKS-AWLISAKQD----LFLYQTYSEILSVFPETGS
LGGGTDITITGDFFDNPAQVTIAGIPCDIRHV--SPRKIECTTRSPGESARLTAPQAGNR
GLLFEVGDAVEDLDLNEATPGYRWQIVPNASSPFGFWSKEGQPFRARLSGFFVAPETNNY
TFWIQADSQALLHFSLSEDPGTKV-KVASIRIGTADWFDSWEQDG---DEGTRQQKTPKL
ELVGGAKYYLEAEHVGIAPSRGMRIGVQIHNTWLNPDVISTYLREKHQIRAHAQRLPEIQ
MLDVSG-IGKFFLTWGNVASQPVSANATAHQIQTAIEELLSVKCKLEPLSANILLRIGFE
HGL-RGSSFDGDRTSSTEPFCGRFSIHQPQHLVLTPPAAQKGYRLHQYTHLCFAYKGHMN
HTLKMTISFIIDFQNTV-KNSTCDWSP----ARTRPESWQFTCTDLWENCVRPSQYLQPL
LANSPVLVHQIHLFPLA---HETDVFYMDEIIIADTNLTVSQVDSGTARPGGNLVESLSV
VGAPPVYNVTLWSAGCGVELPLISARSLPDAGMEG---------GLESVRVTTQRLQRTS
PPLGGHFRIQLSK-TVISGVPVHISAGHLHKLLQKNADDITSRYLNVSDLNVKEDLSSCY
ERVWTLSWSTQIGDLPNFIG---VSDENLTGVDPVATTRVLYDGGVFIGPIFGDMLVTVN
QRPQVVVHVNDIPAHCSGSCSFQYLQMSTPWVHSVWYSLGGEMVTPAILVYITGIGFSND
SQALQITVNRTSCDVVSSNHTHVVCQMDLLPVGVHQISMLV TPSGLAISAHG-RGLFLIV
E PRLDA-VKPPRAAEIGGLWATIQGSSLEDVSLVLFGSQPCAINITTSNSQKIQCKVPPR
GEDG-PIVNVSVVSGDHSSVLPAAFTYVSTLNPVIVSLGRNRSSIA--GGEILFIGMAS-
-LVNYTDLNVEVHIWDTLAQVHTQTARGLEVMLPPLPVGLHRISVSINGVSIRSQGVDLR
IQYITQVFGIEPCCGSLLGGTILSISGVGLSREAALVRVLVGNRSCDIMDSTEENIWCET
PSVPLLPD-ANSLT--APVPVEVWIG NVTFTHGPAPSLAKRGFTFIYEAAATPVVTAMQG
EITNSSLRLYVEGNNISNSVMLLGNLKCDLEAQSS------------RSNVSLSWCSFPL
HALEAGIYPLHVRQKQMGFADMSAVPKQFVIT PQITSIFPTQGSVCGGTVLTVKGV-ALN
SSRGSVQIDLS--GPFTCVILHLGDRTVLCQVKLVGNPLPG-----DTIAL----NVTVF
AN GLTSECWGNCTLFMQEETTPAVDAL TANTSGSLTTMLIRGQRLGTTADELMVFVDDHL
SCDITFFNAS-HVACQISDLTPGQHHLSVFHK RYGYACCGNVSRHFNIFPRVFH YFPKNF
SIHGGSILTIEGRSLRGRNTSSVYIGQQACLTVKV-SAELIQCVVPAASGSMPLEIEID G
SLHHVGVIGYSKVFTPELLSVSQTDD-VLTFVVAQVTGAVDIDIFIGLSPCVGVSG----
NHTVLQCMVPSLPAGEYGVRAYDRVRGWASSVLVFTSRVAVTVVTQNFG-YLGGRLVHVF
GTGFSPGNISAAACGAPCQVLDNATVSAFSCLVLPLDASLAFLCGLKHKEEGCEASSHTY
IQCDLTFTVGTEKLSKSWPYLYICEESSRCLFVPDQWTE---PAFPT-FSGLFISPKVER
DEVLIYNSSCNITMETEAEMECETPNQPITAKITEIWKHWGQNTQGNISFQFCRRWSRA H
SWFPEGVPQDGDNVTVETGQWLLLDTNTSIL-NFLHVKGGKLIFMDPEPTELRAHSILVS
DGGELRIGSEDKPFQGKAQIKLYGNSHSAPFFPYGIKFLAVRNGTLSLHGPLPGVIVTHL
RAAAHARDTVLALEDAVNWYPGDEVVIFSGIGIKDAKPMEEIVIVETVHNADLYLRTPLR
YSHDITEYWVAGEHLVLKATVALLSRSITIRGIFTNEKIRHLVSYKEVNASEGHSQRCLY
SKSEKMLGARDLGARVIIQSFPEEPSRVQLKGVQFRDLGQAFHKYLSSLTLVGA--MSDS
YIQGCSVWNSF-SRGLSMSGTWGLKVDSNVFYNILGHALLVGTYMEIRDT-----SWGFI
PGGKNAFYWLEQGNVIRNNMIISVSGTEGLSSPEMLSPSGIYIRNPTNVVEGNRVCAAGY
GYFFHLVTNKTSQAPLLAFTQNTAHSCTRTGLFVYPKFQPPWDNGIGPTLFQNFMVWGSA
GGAQI-FRSSNLHLKNFRVYSCRDFGIDILESDGNTSVTDSLLLGHFAHK---GSPCMTA
GIKTPRRWELMVLNTIFVNFDLTDCVAIRTCSGCSRGQGGFTVKTKQL--EFPNSSNLVA
FPFPHAAVLEDLDGSLSGKNRSHIIASMETLPASCSVNTSFGQIVHGSVCEEGVLFHRVS
IGLANVPDVAYDLTVTDSRNKTITVNYVGDTLSNVYGWMALLLDQETYTLQFE-TPWIN-
GSLQYSATFDSFALGNHLLLVHSG-LLPYP---HILIKCGSQVGRSLASLPSPHRDQGCD
WFFNSQLRQLTYLVSGEGQVQVTLQVKEGV-PPTISTSTPASESALKWSLPKTWQGVEEG
WGG--HNHTIPGPGDDVVILPNRTVLVDTELPFLKGLYVMGTLEFPVDRSNVLSVACMVI
AGGELKA--GTLDNPLEKEQKLLILLRTSEGVFCDRFNEIRIDPGTIGVYGKVQLHSAYP
KKSWTHLGTDIASGNERIIVKDAVDWRPHDKIVLSSSSYEPHEAEVLSVKEVKGHHVWIH
ERLRHRHVGSDHVMEDGRYIGLAAEVGLLTRNIQIQSDVSCRGRLLVGTFRKSGREEFSG
VLQLLN---VEIQNFGSSLYSSIEFTNT-SGSWIISSALHQSCGGGIHAAASQGIILKDN
IVFGTAGHGIDLEGQDFSLTNNLVVLMTQPAWSTIWVAGIKVNQAKDISLHGNVVAGSEK
LGFHIRGHRCSPLEAFWSENVAHSSLHGLHLYKEDGFDNCTCISGFLSFKNFDYGAMLHV
KNSVQIENITLVDNAIGLLAVVYVSSVPRSAFENVQIVLRNSVIVATSSSFDCLQDKVKP
RSANLTSTDRAPSNPRGGRVGILWPGFTSEPNLWPQEPWHKV-RTGHSIPGTMKLQ-GIT
FSNFVKSCYTNDLDVCILPNEENTGIMHPIIAERTRMLKIKDKSIFYFHPLQP-RKDLEV
-ICPELDCESPRKYLFKDLDGRALGLPPPVSVFPKTEGEWTGSFFN--AGTFQEEQKCTY
QSLIQGYVCQQTDQVVLILDNSDAIWVNRKLYPVVSVTGGFVDTFSSVNTHNPCSASGPV
STFYSILPTSQITKICFVDQTPQVLRFFLLGNKNTSKLLLALFYHELQSPQVFLGENFIP
PTLVQSASSLQNETIGSNHFSIMDNLLYVVLQGEEPVEIRSGVSIHLALTIMFSVLTKSW
KTVILQKLTEFLQVDQDQIRIIYEIPGNERTLKTLADSRAKRKRNCPTVACSSH-YIRVG
HRRPLMMETTT-DRIPPPTSMEALSKVIVFEIGDLPKVRSPGLIPSLSYNKLQNLAYQII
TAQQTGVLESILNMTIEALLV-TQSKGVTD---YGNTSSFKTGNLIYIRPYALSILVQPS
DGEVGKELPVQPQLVFLDKQNRRVELLGTPLEPWSISASLEGTSDSVLT--GCT-QAEIQ
GGYVSFSNLAVLISGSNWRFIFTVTSPP-GVNFTARSRPFAVLPVTRTERSAIILAVSLA
SAVSWLALCCLVCCWLKKSKR--RKTKTEEISESQTNGDKK----P-IHVSSKC------
QGSQIE-TEKEHPVLGEDMRMKVMLG-KS-NLLAHQ-SLNGVCRRKVCRRTVQEES----
-SGQDETVAPAASVAGITSYGQ-TCPPGSPAQQGYLQETGTWKEAQEQLLRYQLAG--QN
QLLV-VCPDLGQERQQWQ-GQCRLIKESGSLGLPQDKKSSCGATESFCLHSAHPKTLQEQ
L-------------------------

Query Results

"ENSGT00780000121902_3"

ENSGT00780000121902_3