ENSGT00780000121845_0 : Linker Region Query Results

------------MKPLPSQQ------P-PPK---MGDFYD---PEH----PTPEEEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSFTKKTLQNRFLT
ALSNEKQSDSPNSPAPPLQVDSNPKVKMDAGDTFPATEESSPPKSRVELGRIHFKKHLLH
VTSRPQLAASTTAASPLPPT----TQLPA-VLAES-MIDSPPSSPPPP----PPPPQASS
PSPPAQ-ISEPVALPQPPATALMTSPPGPLPGDVAVRAQKESPV-KSGPEVLEVDTKQD-
IVSNSLEEHTVQTLKEQADHLLQKEDSHIGKEEEVSDGSK-ISLSSKKASSKKKSSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIDKERDFKKSSAPSKSEDLG-KSSRSKTERDD
RYCSYSKLERDTRYVSSRCRSERDRRRSRS--RSRSDRASRTSLSYSRSERSHYYDSERR
YHRS-SPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRT------SAH---SYRDLRT
S-SSYSKFDRDCKTETSYLEMERRGKYTSKLERESKRTSEHETIKRCCSPPNELGFRRGS
-SYSKHDN-STSRYKSALSK-SISKNDKFKNSFCCTELNEENK-QSHSFSLQTPCSKGSE
LRTINKISEREKTGSPTPSNQLNDSPTFKKLDE----SPVLKP-EFIGHDGRESIKELE-
LSKVKNDQLRNFCSI--ELNVNGSPET-EADVATFCTSKTDAISMTSDDSVTGSEVSP--
----LIKA---CMLSSNGFQNVGRCRERDSDDTCRQHNTSKS-PFREMEPLLSPHHDKLM
SL----PVKTIDYP-----KTLIKE-PVDK-RHSCCKTKDSDIYCSPNEN-------PEA
E-NAEPSAMTISSHSFVN--VHLESKTVICDNREPTDRHSEN-TCDEYK--QSIGSTSSA
SHNHFDGLYEPIGSSGI-SSLQSPPSGI------------RCEENTSPTLDAVE-SKKGI
DFLKYARKETDVG--S-A-LPDSGKGFS-WENRHNNVLSGQS----LQEAQEEGNSILHE
RRGRP--------EIPLDEE-QRGHTHISDDSEVVFP-YDLNLTMEDSDG-IT--YTLKC
DSSGNAP-E---IVSTVHEDYSGSSASSSD-----ESDSEDTESDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDRWED-GLETRRHAYEEEYE----SKGCSQTEKY
F-LHKGTERSAESCYSQFGRK-ADNH---LPDIAHAQSDGVDSTSQTDSRSDHLG-HLNP
EDT------LRAKTSRPQ--ELPVYS-DDFEDLPNKSRQQMIFSNRPDSSRLGKTE-LSF
SSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGTCGTHKYQQSTEHYGGT
HNYWQGNGYWDPRSAGRPPGTGLAYDRIQGQVPDSLTDDREE---EEHWDQRSGSHFSSP
SNKFFFH--QKDKGSVQAPEISSNSIKDALVMNERKD-FSKNFEKNDIKERGPPKKRRQE
LESDSESDGELQARKKVRVEMEQG--ESSVPQHS-ELMGPSCAMDDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSAKPSTEMDTDTPKKLIFR
RLKIISENSMDSAVSDVTSELECKDGKEDLD-QLETVT---VEEDEE-----LQSQQLLP
QQLCESKVESEATIEVSKLPTSEPEADTETEPKD-SNGTKLEETIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VAERGRDAAA
FRDQT-APKTPNRSRERDPDKQSQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPFDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
S--------LAAPPSVPVVPHVAASVEVS----SSQYVAQNE-SVVHQDSNV-PVMPVQA
PGPVQGQNYNVWESNQ-QSV-SVQ-QQYSPAQSQTTIYYQGQTCSTVYS-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTSIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
LSSPAP-VTEPVALPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
IFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLG-KPSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----LPIFKS-EFITHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSELSP--
----LVKA---CMLSSNGFQNISRCKEKDLDDTCMLHKKSES-PFRETEPLVSPHQDKLM
SM----PVMTVDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTLNDS-NPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSKKSS
EFLKHAGKETIVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPE
RRGRP--------EISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSND-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESI-ASKACPQTDKF
F-LHKGTEKNPEISFTQSSRKQIDNR---LPELSHPQSDGVDSTSHTDVKSDPLG-HPNS
EET------VKAKIPSRQQEELPIYS-SDFEDVPNKSWQQTTFQNRPD-SRLGKTE-LSF
SSSCEIPHVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGACGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SDKFLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVDSETNIEASKLPTSEPEADAEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TTERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKAS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPD------
----------------------RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----VPLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
PSSPAP-VTEPVSLPHTPITVLMAA-PVPLPVDVAVRALK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQNLNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTSSKKKYSQSEG
NFLGSESDEDSVRTSSSQRSHDLKYSASIEKERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRCDRGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEDYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAMKRCCSPPNELGFRRGL
-SYSKHDS-SASRYKSILSK-PIPRSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGNE
LRMINKNPEREKPGSPSPLNRLNDSPTFKKLDE----LPIFKS-EFIAHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKADAVLMTSDDSVTGSEVSP--
----LVKA---CVLSSNGFQNISRYKENDLDDTCMLHNKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDS-NPSLCNSEA
E-NIEPSVMKISSNSFVN--VHLESKTVITDNRNLTD-HSKF-ACEEYK--QIVGSTSSA
SVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLL----KCGENVSPGLDAVLKSKKSS
EFLKRAGKETIVEVGSD--LPDSGKGFTSREKRHNNGLSGKC----LQEAQEERNSVLPV
RRGRP--------EISLDEGGERGRMHTSDDSEVVF-SCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSHSYRHYSDHWEDERLESRRHSYEEKFESI-AGKACLQTDKF
F-LLKGTEKNPEISFTQSSRKQVDNH---LPELSHPQSDGVDSTSHTDVKSDHLG-HPNS
EET------VKAKIPCRQ-QELPIYS-SDFEDVPSKSWQQTTFPNRPD-SRLGKTE-LSF
SSSCEISHVDGLHSSEALRNLGWDFSQ-EKPTTTYQQPDSSYGACGGHKYQQSAEQYGGT
RDYWQGNGYWDPRS-GR-PGTGVVYDRTQGQVPDSLTDDQEE---EENWDQQVGSHFSDQ
SNKFLVSL-QKDKGSVQAPEISSNSIKDTVAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRMEVEQE--ETSVPPGS-ALIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEVITNFFY-------------FQTSSQWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESR
VLPIIQRWSQTKTAIPPLSEGDGYSSENTSRAHTPLNTPDPSMKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-PLENIP---VEEEEE-----LQSQQLLP
QQLPECKVDSEMSGEASKLPTSEPEADAEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVA
FRDQIPAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPASAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVTQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQSQPLQPSEMIVTNN-L
LDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

MQ-------SC---NIQERQPSAIEKVLDLKLDDLGSNLCS-----ATYLCDLGEEENEG
KIENVQKMGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNDKQNDTPNSPAIPLQADFVPKIKMDPGDTSTITEESSPPKPKVELGKIHFKKHLLH
VTSKPMLAAVTPVAASPPLP-----IIPSPIVTESVVTESPPQSPPPP----PPALQVRT
PSPPAP-MSVITALPQIPTSVPVGTSLQSPPIDVAIRTSK-ESLNTVVLESLELDTKQD-
TCSSELLDIVSQNVSENVDVSPQKEDSHIGKEEETPDSSK-SSLCYKKTSSKKKFSQSEG
MFLGSESDEDSVQTSSSQRSHDFKNSASVEKERDSKKSLPTLKVEDLG-KSSRSKTERDD
KHFSYSKMDRDSRYVSSRSRSERERRRSRS--RSRSDRGPRTSSSYSRSERSHYYESERR
YHRS-SPYRERPRYSRSYTDNRMRESSDSEEEYKKIYSRSS-DSRRTSSHS-SFYRDSRT
--SAYSKSDRDSKLESFHMDAEKRGKYSSKPERESKRTSENELMKRCCSP-NEMGCRRGA
-SYSKHES-NTSRNKSAPWK-STQKPDKFKSSFCCTESTEEIKHQSHSLNLQTTCSKSNE
LRMVVKIPERDKTMSPSSTNRLNDSPTFKKRGE----SPIFKS-EFMGNDSHDSIKELDT
LSKGKYDPLRTYCPM--ELNVNGSPGE-GSDLVTFCASKTEDIFTSSDDSINRSEVSP--
----LIKTNKSCVLPSNGFQSINRSKEKDLDDSSVQHSELNS-SLKEMDPSVPSQQDKFE
SF----PVITVDYS-----KTIKE--SVDL-RVSYCKTKDLDSCNTSNDN-SPSLYQFET
E-NIEPTVIKVIPNSFMNQ--DSDLQSVICDNKNRKNLHSVQPTSEESEQNLRVK---LA
SVNPC-DSDSPVESSSL-ASVCSLTLGMKVDNPSVIQ---HVEGKLPPGLDASPQNQ-ST
EFLKHTVIE-MIELNEQQITPETGKRVVPWKNRHNSGLLMESLQTEDEEVQEEANASLPS
GREKAA-----STEESFKKQEGSRNMLISGASEPLFSSCDMSGLVE--GDSIA--HAPKC
DSSGNAS-E---FVSPIHADYSDSSQSTSD-----ESDTEDTDSDDSSIPRNRLQSVVIV
PKKSTLPLEETSPCSSQSSQVNRHYSDHWEDDRPDSS-KSYDERFEEM-MSKNFSQTEKF
S-LPKGVDKSPEVPYIESNRKQMDDF---ELETAQPQSDGVDSTSQADVVSDTIGLQNLE
GT-ASKESSVVTKPILRQQEELPPYSSEGLEGTLMKSRQQNNFPNRPD-SRLGKADSDNF
SSSGDFSRVDGFHSAEDLGNLGWDFSQPEKPSTTYQQPDSSYGLYAGCNYQQSSEQYRST
HNYWQGNGFWDPRLANRPP--GIVYDRIQGHIPDSLTNDHEE-EDDENWNDPRRPHFSNQ
SSKFLAQL-HKEKGSVQAHEISSNSSKDLSVVNEKKV-SPKNLEKGDMKDRGPPKKRRQE
LESDSESDSDMQDRKKVRVEVEQL---ETLPSGS-ALVGPLCVMDDFRDPQRWKECARQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPVSKDDRAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTQSQ
SC-LKSFLE-CHGLSLLWIWMAELGDGRGN---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAIPHFSEGDGYSSENTSRAHTPLNTPDPSTKPSTEADTDTPKKLVFR
RLKIISENSMDSAISDATSELEGKDCKEDLD-QLENAP---VEEDEESQPQQLQPQQLTL
QHLPPSKGDIETPVDSSKPPASEPETEHEAEAKE-SNGPKLEEPIAMETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENN----GDRGRDAIG
LRDQAATPKTPNRSREREPERQTQS-KEKKKRRSSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRLKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYESL--GYSGP
HHSFVGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPMCSPAT-----YEHSQN-LGHSVE
PS-------LTTPQPVPVVQHVATPMEVS----TSQYVAQNE-AVVHQESNV-AVLPASA
SGPVQGQSYSVWDSNQQTVT---VQQPYSPAQSQTAIYYQGQTCQTVYG-VTSPYSQSTP
PIVQNYPQAAGLQYIQGQQIFTAHPQSVVVQSTAAVTTIVAAGQPQPLQQPELVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDEANLEHEA
EMDLGTPTYDENPMKSS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGTVYKPK--------EDTDLE

---------------------------------------------------PLGLQAHAA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLPAAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VTAESTTVDSPPSSPPPP----PPPFQATT
LSSPAP-VTEPVALPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEAGTKQD-
TVSNSSEEHIIQILNEQADISSKKEDSHIGKDEEIPDSSK-INLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQKSHDLKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYADNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEMK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----LPIFKS-EFITHDSHDGIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSELSP--
----LVKA---CMLSSNGFQNVSRCKEKDLDDTCMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDS-NPSLCNSEA
E-NIEPSVMKISSNSFMN--MHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSKKSS
EFLKHAGKETIVEVGSD--LPDSGKGFVSRENRRNNGLSGKC----LQEAQEEGNSILPE
RRGRP--------EISLDERGEGGRVHTSDDSEVVFSSCDLNLTVEDSDG-VT--YALRC
DSSGHAP-E---IVSTVHEDYSGSSESSND-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ASKACPQTDKF
F-LHKGTEKNLEISFTQSSRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDPLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDVPNKSWQQATFQNRPD-SRLGKTE-LSF
SSSCEISRVDVLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGACGGHKYQQNTEQYGGT
RDYWQGNGYWDPRP-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKFLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPFTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVDSETNVEASKLPTSDRISKQSPFPP---------------------------
-----------S--------LITLPLVYFLQEVYRIPKKSQTEKENT---TTERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKAS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

----------------------------------------------------------QG
KTETVQKAGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLT
GLGNEKQNETQNSPAVPLQTEFNPKIKMDLGDAAGSAEESSPPKPKVELGKIHFKKHLLS
VTTKPPPPAAAVTL--PPSALAPV---TEPV---AAAADFPSTPPPPPPPPPTASPAASM
P------VPAAAALPQLPVTLMSTL--LLSPPVEAEVPASKEPCRVVPKEALELDVKQD-
AVSHGLEEHVTVHTAEQVEITPQKEDSHIGKDDEVADSSKGASLCSRKQGSKRKFSQSDG
ALLGSESDEDSVRTSSSQRSHELKIS-SAEKERDPRKSSASLRGEELVKSSSRSKSDRDE
KYSSYSKSERDSRYSSSRSRSDRDRRRSRSHSRSRSDRGSRTSSSYSRSERSHYYESDRR
YHRS-SPYRERTRYSRSYADSRARESSDSEDEYRRTHS-RSSDSRRTSSHS-SSYRDSRT
---SYSKSDRDSKIESSHGDMERRGKSSSKADRDSKRTSESEVTKRC-SPLNELGYRKGT
SHSKPDSNVNSSRYKSTPSKTPAPKPDKFKSSFCCTESVEEIKQQSNSLDLETSCLKSNE
IRVSI-AKRFEREKTLSPLNQLNDSPTFKKTDESKAGFPHSRSEEVAGNECHDSVKEQET
LVKVKHEQLRTCFPM--EMNINGSPEGRSDDLATLSASKPEDVTVSSDDSLCRSEVSP--
----VVKTSKSYPLPSNGFESTYASKEHELGDSRVQSSECSS-LFKETEAPVPEQQ----
CEAMPLPVVNVDHS-----KTLIKKLDDQA--TPCDKTKESVFCYISDDA-TPSLYHSEV
EIEAEPADLKVTSEAFLD--VHVEPQTVTCDYESPEDQNSKS-ACEDDQYHMNHAH----
------KTSLAVDSSSRDSSQDGYSPRIRLDNPMVAQ---HPEGNVPSKWDRAPPSQ-CE
RPAHHSEAEEMLEVDTRHVDLPSAKGKLSFKDEHSYYSELPPEHRSREVVVEE--SAVST
EGLGSDDLKEQGLGTSIE-DAGNGPLVASAFPDALFPSCDVVVTAEETET-LTQA--PTC
DSSGGAS-DF---VPARHDDYSDTAESDSEAGS-DDSETEDSDSD-DGMPRKRLQSVVVV
PKNSTIAMEESSPCSSRSSQGNRRYSDHWDDERPEPSRPYYEERPENT-TSKNGLQAESR
C-SPRGMEKSPASS-TELSRKEPEEL---RPDACQPQSDGVDSTSQADLAADSDGKPNQD
ER--LKELVSAGRPGGLQ-EEQPFCLPESLESADNS-RHQTNAS-QPD-SRQGKGG-LNQ
SGLGEFSKVDGFHTAEDLGGLGWDFSQPEKPSSTYQQPDSSFGVYSGYVYQPGSGAYGGS
QNYWQGNGYWDARSASRP--SGINYERIQGQVPDSLTEDHEEYEEDDRWDDECKARFPSS
PSKFHAP-EQKEAGSVQAHEISSNSTKEPGSAGEKKE-EVKALEKNDVKERGPPKKRRQE
LESDSESDGDSRERKKVKAEGEQA---EAAPQD-SSMVGRLCIMDDFRDPQRWKEFAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMLCECPPLSKEERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQKKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-CHGLSLLWIWMTELGDGRGSTANNLKLQLEIMKTLELLPIPTKNMLEESK
VLPIIQRWAQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDLSAKQSVEGDTDTPKKLVFR
RLKIISENSMDSAISDTTSELEGKEGKEDLD-QLEGAPTEASE---EQQQQ---------
---QEMKPAGDVPVESSKPQVVELEAEPEVEVKE-SNGAKLEEPITMETPSQDEEEGVSD
VESERSQEQTDKIVDVSDLATRLLDSWKDLKEVYRIPKKSQAEKESS---AADRGREASG
HRDQTPTPKNPVLSRERDPERQSQS-KEKKRRRDSLSPPSSAYERGTKRPEDRQVVPGN-
P-PWHRFWVRGSTARAKARKPQKRPKTHGN--PQK---RRAPRFSPALPFTRAASRVNSP
RRFLGKIPPAAPRLGTKIPKSSEKKKKSRGTARNEPWASPKSQKKKELRRGQPTEG----
---------IGVGGLGPLRPHVATPLEVTP---PPPYVPQGD-PVGHQEANV-ATVAHRA
QSGADCQNYGVWDSSQQA-V--AVQQQYSPAQSQPAIYYQGQTCQTVYG-VTSPYSQTTP
PIVQSYAQPGL-QYIQGQQIYTAHPQGVIVQPPTAVTTIVAAGQPQPIQQPELVVSNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDP PTWDSPGDDASLEHEA
EMDLGTPTYDENPMKSS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAIYKPK--------EDTDLE

---------------------------------------------------PLGLQAHTA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-VTEPVALPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGL
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDSIKELDS
LSKVKNDQLRSFCPT--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSNNPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCEENTSPVLDAVLKSRKSS
EFLKHAGKETIVEVGSY--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGRVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ASKACLQTDKF
F-LHKGTEKNPEISFTQSSRKQIDNH---LPELSHPQSDGVDSTSHTEVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDVPNKSWQQTTFQNRPD-SRLGKTE-LSF
SSSCETSRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSI-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEVSSHLACLFLKT-TILIESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTDADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVESETNIEASKLPMSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQAEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVTQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPATAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITSVQRIKLP---------------
-----------NVFPTS-KKPKTAEADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MERRGKYSL---RESKRTLENEAIKRCYSPPNELGSRRGS
SH--KHDS-SASRYKVPSNL-P--KSDKE-NSF----WTENEE-ISHSFRLQSPCSKGSD
LRMISKIPEREKARSPSPSNRLNDSPTFKKLDE----SPIFKS-EFIGHESHDSIKEFDS
SSKVKNDQVRSFCPV--ELNINGSSGA-ESDLATFCTSKSDAVVMTSDDSVTGSEVSP--
----LVRA---CVISSNGFQNV-RCKEKDLADTRMQHHKSES-PFRETEPPMSPHQDKLK
SL----PVMTTDYS-----KTVVTE-PVDV-RVACCKTKDSDIDCTSNDN-NPSLCYSEA
E-NAEPSVMKISSNSFMD--VHLESR-AVCDNTNLTDQHSQF-VCEEYK--QGVGSTSSA
SVNHFDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXX-XX-XX
XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX----XXXXXQEGNSVLPD
KRGRP--------GIPLDGGGGRGCVHTSDGSEVVFS-CDLNSTLEDSDG-VT--DTLRC
DSSGHAP-D---IVSTVHEDYSGSSESSSE-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYTDHWEDERLESRRHSYEEKLESL-ISKTCPQTEKF
F-HHKGTEKNSEVSFTQFSRKQVDNH---LPEIAHPQSDGVDSTSHTSVSADLLG-HPNS
EKM------VKAKISSRQHEELPVYSSDDFEDVPNKSRQQTTFPNRPD-SRLGKTE-ASF
FSSCEISRVDGLHSPEELRNLGWDFSQQEKPTTTYQQPDSSYGACGGHKYQPSAEQFGGA
RCYWQGNGYWDPRSAGRPAGTGVVYERIQGQVPDSLTDDREE---EEHWDPRGGPHSFSQ
SSTLLPSL-QKDRGSVQAPEISSNSSKDSLAVNEKKD-FSKNLEKNDIKDRGPPKKRRQE
LESDSESDGELQHRKKVRLEVEQG--ETSVPPGS-ALTGLSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECAPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQXXXXX
XXXXXXXSG-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKMSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKDDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPEPKVDSETTMEASKLPISEPEADTDTEPKE-SNDTKLEETIAEETPSQDEEECVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKXXXXXXXXXXXXXXXX---XXXXXXXXXX
XXXXXXXX------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQ--QQMQNLGMTSPLPYDSL--GYNAP
HHPFVGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPVP-----YDHAQPLVGHSAE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYGVWDSNQQSVS--V-QQQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QNIPGPQIYPAHPKEVP-QPTAAIA--IVPGRPRLRXXXXXXXXXXXX
XXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXQTQWDPPTWESPGDEASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCK------------------------
-----------------------

--------------------------------------------------------EKCA
KIESVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAL-SQGDSTPKIKVDIGDTLATTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTSAVASPSPPP----VQLPA-VIPESTTIDSPPSSPPPP----PPPPQATT
PSSPAP-ITEPVASPHTPVTVLTTA-PLSLPVDVAVRTLK-EPPVTLVKESLEVDTKQD-
IISNNSEEHITHNLNDQVDSPSPKEDSHIGKEEDIPDSSK-ISLSSKKPVSKKKYSQFEG
SFFGSESDEDSVRTSSSQRSHDLKISASIEKERDIKKSSAPLKSEDLG-KSSRSKTERED
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRGSRASLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRGRESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLDIERRGKYSSKLERESKRTSENEAIKRCCSPPSDLGFRWGS
-SYSKHDY-SASRYKSALSK-SIPKSDKFKNSFCCTELNEESK-QSHSSSLQTPCSKGSE
LRTVSKIPEREKTGSPSASNRLNDSPTFKKLDE----SPIFKS-EFIGRDSHDSIKELDS
LSKVKNDKLKNFCPI--ELNINGSPGA-ESDVTTFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CISSSNGFQSISRCKEKDL-DTCMQHSKSQS-PFKETEPLVSPCSD-NM
SL----PVMTTDYS-----KT-EKE-PVDM-RVSCCKTKDSDRYCTANES-NPSL----S
E-TVEPSVTKISSNSFKN--VHLESKTVVCDKRNLTDQHSKF-TCEEYK--QSVGSTSSA
SVNHLDDLYEPIGSSSIGSSLQSLPPGIK---------------V--DILDGVLKSKKST
EVLKHTGKEKIVDVGSG--FSNSGKAFASWENRHNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLD-EGVRGHAHTSDDSEVVLSSCDLNLTVEDD--GVT--YTLKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDHWEDERLELRRYSYEEKFENI-TSKGCPQTEKF
F-FHKGTEKNPEISFIQSSRKQVDNH---LPEIAHSQSDGVDSTSHTDMKSDLLG-HSNS
EEI------TKAKTSFRQQDELPVYS-DDFEDIPSKSRQQTTFPNRPD-SRLGKTE-LNF
S-SCDISCMDGLHSSEELRNLGWNFSQQEKPTTTYQQPDSSYGVCGAHRYQQSAEQYGGV
GTDWQGNGYWDPRSAGRPPGSGVAYDRIQGQVPDSLT---------ENWDQRGESHFLSQ
SNKFLLSL-QKDKGSVQAPEISSNSVRDSLAVNERKD-FSKNLEKSDIKDRGPLKKRRQE
LESDSESDGELQDRKKVRVDIEQG--GTSVPPGS-ELIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTTAPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTP------
------------------------------------------------------------
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------------------------------------------------------------
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-----------------------

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
LSSPAP-VTEPVALPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKPSQSEG
IFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----LPIFKS-EFITHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSELSP--
----LVKA---CMLSSNGFQNISRCKEKDLDDTCMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTVDYS-----KTVVKE-PVDT-RVSCCKTKDSEIYCTSNDS-NPSLCNSEA
E-NTELSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSKKSS
EFLKHAGKETIVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPE
RRGRP--------EISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSND-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFENI-ASKACPQTDKF
F-LHKGTEKNPEISFTQSSRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDPLG-HPNS
EET------VKAKIPSRQQEELPIYS-SDFEDIPNKSWQQTTFQNRPD-SRLGKTE-LSF
SSSCEIPHVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGACGGHKYQQNAEQYGGT
HDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQRDGSHFSDQ
SNKFLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTETDTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVDSETNIEASKLPTSEPEADAEIEPKE-SNDTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TTERGRDAVG
LRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKAS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
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--------------------MEERGKDSSKLEGESKRTSENEAMKRCYSPTNEQGFRRGS
-SYSKHGN-SASRYKSAPSK-PAPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMISKVTEREKIGSP-PSNRLNDSPTFKKLDE----SPVFKS-EFIGHDSHDSIKELDS
LCKVKNDQLRSYCPT--EFNINGSPGA-ESDLATFCTSKRDTVLMSSDDSVTGSEVSP--
----LVKT---CMLSSNGFQNINRCKEKDLDDTRMQHNKLES-PFRETEPPVSPHQDQLI
SL----PVMTIDYS-----KTIVKE-PVDV-RVSCCKTKDSDIYCTSNNR-R-SLYHSGA
E-NTEPLVTKISSNSFMN--VHLKSKTVICDNGSLTDQHSKF-ACGEYK--QSVGSTSSA
SVNHFDDLYPPTGSSCIASSLQSLPAGTNVDSLTLL----QCGENTSPVWDAVLKSK-SS
EFLKHAEKE-IIEVGSG--LPDSGRGFASWENRHNNGLSGKC----VQETQEKGNSILPD
RRGRP--------EISLDEEGGRGHAHTSDDSEVVFSSCDLNLIMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDLEDTDFDDSSIPRNCFQSVVVV
PKNS-LPMEETSPSSSRSSQSYRHYSDHWDDERLEPRRHSYEEKFESI-ASKACPQTEKF
F-HKA-TEKD-SESLTQPIQKQIDNH---LSEIAHPQ-DGVDSTSHTDIKSDPLG-HPNS
EEA------VKARITSRQQEELPVYSSDDFEDVSSKSRQQTTFANRPD-SRLGKTE-SNF
S-SCEISRVDGFRSSEELRNLGWDFSQQKKPTTTYQQPDSSYGACGGHKYQQSAEQYSGT
RNSWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EEN-DQRGGSHFSGQ
SNNFFLSL-QKDKGSVQAPEISSNSIKDSLAVNEKKD-LLKNLEKNDMKDRGPLKKRRQE
LESDSESDGELQDRKKVRVEVEQG--ETAVPLGS-ALVGPSCVMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSIEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---IEEEEE-----LQSQQLLT
QQLPESKVDSEIAVEAIKLPTSEPEADTEIEPKE-SNGTKLDEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---ITERGRDAVG
FRDQTVAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDHNQLSTEERRKLFEQEVAQWEAQKKQ-QQMQNLGMTSPLPYDSL--GYHAP
CHPFAGYPPGYPMQAYVDPSNPNAGK-LLPTPSMDPVCSPSP-----YDYSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-TVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATIYYQRQAGPTVYG-MTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPATAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

----------------------------------------------------------QG
KPETVPRAGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLA
ALGNEKQNETPTPPAVPVPTDFNPKNKLDLGDTASSAEESSPPKPKVELGKIHFKKHLLN
VTAKPPPA-----------PATPV---TEPV---AFAVDLPPTPPPPPPPPP--PPASPM
P------VPGATAP---LVTPMPAL--LLSPPGEAEAPVPREPSQALPREAVEPDAKQD-
PASRGSEERVTPPAPEQTEVTPPKEDSHIGKEDEVSDGSKGAPVCSRRQGAKRKFSQSDG
ALQGSESDEDSVRTSSSQRSHEQKIS-STEKERDPRRSSASHRSDDVGKSSSRSRSDRDE
KYLSYSKSERDSRYSSSRSRSDRDRRRSRSHSRSRSDRSSRTSSSYSRSERSHYYDSDRR
YHRS-SPYRERSRYSRSYADSRARESSDSEDEYRRTHS------RRTSSHSSSSYRDSRS
---SYSKSDRDSKVESSHADVDRRGRSSSKADRDSKRTSESEVSKRC-SPLDELGYRKGT
SHSKPDSNVNSSRYKSTPSKAPAPKPDKFKSSFCCTESIEEIKSKSNSLDLETSCVKNNE
IRVSS-VKKLEREKTLSPLNQFNDSPALPKANESKAGLANSKSEELAANKGHDSVKEQEP
FLRAKHDPLRMCFPT--ESSVNGSPEGQDEGLATSSACKAEDVAASSDHGPGRSEASP--
----AINTSPSYPLPSNGFESTDVSQEQELDDSRVQSSECNS-LFQEAEAPEPE-QP---
EEAAPLPAVNVDPT-----NTDLNKLDEEVTHTLCDKTKEPVFCYISDDA-TPGLYHSEV
EIEAEPADLKMTSETFLD--VQVEPQTVTCDYESAEDSHSKS-AGE--DEHGHPSH----
------KISLAVESSSRDSSQDGCSQRLQSDHPML-------EESVSSKWDVPPPGV-CQ
EPLQHSEAEEMLELDAQHVDLGSAKGKLSFQNEHSYYSEVPLEHRSR-------------
EGAELDELRVQSPGVSAERDEGSEPLVASAFPDTLYPSSDVIVTADDTEM-VTQA--PTC
DSSGNAL-E---FIPAGHDDYSDSGDSNSEGGS-EDSDTEDSDSD-DGTPRKKLQSVVVV
PKNSTIAMEESSPGSSR---SNRRFSDHWDDERPEPSRPYYEERSENM-GSKGGPQVESR
C-SPRGMEKSPATS-TELSRKELEEL---RADPCQAQSDGVDSTSQADLTADSHGKAGTE
ERLGLPDAVTMGRPMGRP-EEQPFCIPESLESTDTS-RHQMSSS-KPD-SRQGQGG-LNQ
SGLGDYSRLDGFRAPEEMGAVG-DFSQQEKPSSTYQQPDSSFGMYSGYVYQPGPGAYPSS
QSYWQGNGYWDARAASRA--SVVNYERIQGQVPDSLTEDHEEFEEDERWDEECKPRFPSP
SGKSQMP-EQKEKGSVQAHEISSNSTKEPVPGGEKKD-EAKALEKNDVKERGPPKKRRPE
LESDSESDGDSGEKRKGKLEGEQV---EPAPQD-SSMVGRLCIMDDFRDPQRWKEFAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMLCECPPLSKEERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQKKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSSNCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-CHGLSLLWIWMTELGDGRGSTANNLKLQLEIMKTLELLPIPTKNMLEESK
VLPIIQRWAQTKTAVPQLSEGDGYSSENTSRAHTPLNTPELSAKQSVEGDTDTPKKLVFR
RLKIISENSMDSAISDTTSELEGKEGKEDLD-QLEAAPVEVME---EQQQ-QQ-------
-ISQDIKTAVEAPVESSKSQPAELEAEPEAEVKE-SNGAKLEEPMAMETPSQDEEEGVSD
VESERSQEQTDKIVDVSDLATRLLDSWKELKEVYRIPKKSQAEKESS----AERGRDTGG
LRDQTPTPKNPILSRERDPERQSQS-KERKRRRDSLSPPSSAYERGTKRPEDRQEG-TS-
SKKKVRPKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLQNLGMTSPLPYDSM--GYGTP
HHSFMGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDSMCSPAG-----YEHSQTLVGHTVE
PA-------LSTPQPVPVVQHVAT-T---MEVITPQYVAQSD-AVVHQEANV-AVLPVAA
AGAVQSQSYGVWDSSQQPAV--AVQQPYSPAQSQPAIYYQGQTCQTVYG-VTSPYSQTTP
PIVQSYAQPGL-QYIQGQQIYTAHPQGVIVQPPTAVTTIVAAGQPQPIQQPELVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDPPTWDSPGDDASLEHEA
EMDLGTPTYDENPMKGD-RSDPGSFG--VAPLATLGARLFQPQLEWAPDFLKFC--PEFQ
PLCGAGQKSGNEGEKYLGNRSTLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGILYKPK--------EDTELE

------------IKSIWP-H------E-KPA---FGPSYC---P---LLQDGNREEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAGPLQVDLTPKIKMDIADTLSTTEDSSPPKSRVELGKIHFKKHLLH
VTSRPLLTPATAVSSPPPPI----APLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
PSPPAP-VTEPVALPHTPIPVLMTA-----PVDVAVRALK-EPPVTTVPESSEVDTKQEA
AVSNSSEEHITQNLNEQVDIASQKEDSHIGKEEEIPDSSK-SNLGSKKTGSKKKSSQSEG
TFLASESDEDSVRTSSSQRSHDLKFSASIEKERDSKKSLAPLKNEDLG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERARYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-FSYRDLRT
S-SSYSKSDRDCKTESSYLEMEKRGKYSSKLERESKRTSENEAMKRCCSPPNELVFRRGS
-SYSKHDN-SASRYKSTLSK-SISKSDKFKNSFCCTELNEEIK-PSHSSNLQAPCSKGSD
LRMISKIPEREKTGSPSPSNRLNDSPTFKKLDE----SLIFKS-EFIGHDSHDSIKELDS
LSKVKNDQLRSYCPI--ELNINGSPGA-ESDLATFCTSKADTVLMSSDDSVTGSEVSP--
----LVKG---CMLPSNGFQNVNRCKEKDSDDSCMLHSKSGS-PFREAEPPVSPHQDKLL
SL----PVMTIDYS-----KTVIKE-PVDM-TVSCCKTKDSDICCTSNDK-NPSLHHSEA
E-KIEPSVMKISSNSFMN--VHLKSKTVICDNRNLTDQHSKF-ACEEYK--QNVGSTSSA
SVNHFDDLYQPIESSGIASSLPSLPPGIKVDSLTLL----QCGENTSPVLDAVLKSK-ST
EFLKHAEKETVAEVGSG--LPDSGRGFASWENRHNNGLSGKC----VQEAQEEGNSVLPD
RRGRA--------EISLDEEGGRGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESV-ASKPCSQTEKF
F-HHKGTEKNLEVSFSQPSRKQIDNH---LSEIAHPQSDGVDSTSHTDVKSDFLG-HPNS
EET------TKAKIASRQQEELPVYSSDDFEDVPSKSRQQITFPNRPD-SRLGKTE-LSF
SSSCE--RVDGFRSSEELRNVGWEFSQQEKPTTTYQQPDSSYGACGGHKYQQSAEHYGGT
RNYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EENWDQRGGSHFSTQ
SSKFFLSF-QKDKGSVQAPEISSNSVKDSLTVNEKKD-LSKNLEKNDMKDRGPPKKRRQE
LESDSESEGELQDRKKVRVAVEPG--ETAVPPAS-ALVGPSCVMEDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKFYIKGTCE
FY FFNHSVVPFHIKIAFDYCCHKYRKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAIPQLSEGDGYSSENTSRAHTPLNTPDPSAKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLT
QQLPESKVESEITVEASKLPTSEPEADTEIEPKE-GNGPKLEETIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQTLGMTSPLPYDSL--AYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPNMDPVCSPAP-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSE-GVVHQDSSV-TVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQNYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

--------------------M-----R-LEH---FG---------V----LFLREEENEA
KIENVQKTGFIKGPIFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFFT
ALSNEKQSDSPHSPATP-QVDSNPKAKMEAGDTFPATEESSPPKSRVELGRIHFKKHLLH
VTSRPQLATTTTVASLLPPT----TQLPV-AIAES-TVDSPPSSPPPP----PPPPQVSS
PSPPAP-ISEPVALPHPPVTALMTSTPGPLPVDAAVRAQK-EPPMKSVPESLELDMKQD-
IVSNSLEEHTNQTLKEQADNALQKEDSHIGKEEEVSDGSK-ISLSSKKASSKKKSSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIEKERDFKKSSAPSKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSTRCRSERDRRRSRS--RSRSDRVSRTSLSYSRSERSHYYDSERR
YHRS-SPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRT------SAH---SYRDLRT
S-SSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSEHEAIKRCCSPPNELGFRRGS
-SYSKHDNNSTSRYKSALSK-SISKSDKFKNSFCCTELNEENK-QSHSFSLQTPCSKGSE
LRTINKIPEREKTGSPSPSNQLNDSPTFKKLDE----SPILKP-EFIGHDSHESIKELE-
LPKMKNDQLRNFCSI--ELNVNGSPET-ETDVATFRTSKPDAISMTSDDSVTGSEVSP--
----LIKG---CVLSSNGFQSVGRCRERDADDACRQHNKSKS-PFRETEPLLSPHHDKVM
SL----PVKTIDYS-----KTLIKE-PVDK-RHSCCKTKDSDRYCSPNES-------SEA
E-NR-----EISSNCFVN--VHLDSKTVVCDNRELTDQHSEF-TCDGYK--QSIGSTSSA
SLNHFDDLYESVGSSGI-SSLQSLPSGI------------RCEENTSPALDTVQ-SKKGI
DFLKYVGKETDVV--S-A-LPDSGKAFS-SWENRHNMLSGQS----LQESQEEGSSTLHE
RRGRS--------EVSLDEEEQRGHTHISDDSEVVFP-YDLNLTMEDSDG-VT--YTLKC
DSSGNAP-E---IVSTVHGDYSASSASSSD-----ESDSEDTESDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWED-GLESRRHAYEEKFESM-ASKGCSQTEKF
F-LHKGTERNPETSYSQFSRK-IDNH---LPEIAHSQSDGVDSTSHTDVKSDSVG-HLNS
EDA------IRAKMSRPQ--ELPVYC-DDFEDLPNTSRQQMIFSNRPDSSRLGKAE-LSF
SSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGTCGTHKYQQSAEHYGGT
HDYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EENWDQRSGSHFSSP
SNKFFFH--QKDKGSVQAPEISSNSIKDSLVINERKD-FSKNFEKNDIKERGPPKKRRQE
LESDSESDGELQARKKVRVEIEQG--QSSVPQHS-ELVGPSCAMDDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSAKPSTEVDTDTPKKLIFR
RLKIISENSMDSAVSDVTSELECKDGKEDLD-QLETVT---VEEDEE-----LQSQQLLP
SQLCESKVESESTIDVSKLPISEPEADTETEPKD-SNGTKLEETIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VTERGRDTAA
FRDQT-APKTPNRSREREPDKQSQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPFDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
S--------LAAPPSVPVVPHGAASVEVS----SSQYAAQSE-SVVHQDSSV-PGMPVQT
PGPVQGQNYSVWDSNQ-QSV-SVQ-PQYSPAQSQATIYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKPLPSQPP-----P-PPK---MGDFYD---PEH----PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSFTKKTLQNRFLT
ALSNEKQSDSPNSPATPLQVDSNPKVKMDTGDTFPATEESSPPKSRVELGRIHFKKHLLH
VTSRPQLATTITVASPLPPT----TQLPA-VIAES-TIDSPPSSPPPP----PPPPQASS
---PAP-ISEPVALPQPPVTALMTSPKGPLPVDVAVRAQQKEPPVKSVPEFIEVDTKQD-
IVSNSLEEHTIQTLKEQADNLLQKEDSHIGKEEEVSDGSK-ISLSSKKASSKKKVSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIDKERDFKKSSAPSKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERDRRRSRS--RSRSDRASRTSLSYSRSERSHYYDSERR
YHRS-SPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRT------SAH---SYRDLRT
SSSSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSEHETIKRCCSPPNELGFRRGS
-SYSKHDN-STSRYKSALSK-SISKNDKFKNSFCCTELNEENK-QSHSFSLQTPCSKGSE
LRTINKISEREKTGSPTPSNKLNDSPTFKKLDE----SPILKP-EFIGHDSHESIKELE-
LSKVKNDQLRNFCSI--ELNVNGSPET-EADVATFCTSKTDAISMTSDDSVTGSEVSP--
----LIKA---CMLSSNGFQNVGRCRERDSDDTCRQHNTSKS-PFREMEPLLSPHHDKLM
SL----PVKTIDYS-----KTLIKE-PVDK-RHFCCKTKDSDRYSSPNES-------SEA
E-NTEPSVMKISSNSFVN--VHSESKTVICDNRELTDQHSEF-TCDEYK--QSIGSTSSA
SLNHFDGLYEPIGSSGIISSLQSLPSGI------------ICEENTSPTLDAVQ-SKKGI
DFLKYAGKETDVG--S-A-LPDSGKGFS-WENRHNNVLSGQC----LQEAQEEGNSVLHE
RRERP--------EIPLDEEERRGHAHISDDSEVVFP-YDLNLTMEDSDG-IT--YTLKC
DSSGNAP-E---IVSSVHEDYSGSSASSSD-----ESDSEDTESDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWED-GLETRRHAYEEKYE----SKGCSQTEKY
F-LHKGTERNPETSYSQFSRK-VDNH---LPEIAHSQSDGVDSTSHTDLKSDPLG-HLNS
EDT------LRAKTSRPQ--ELPVYS-DDFEDLPNKSRQQMIFSNRPDSSRLGKTE-LSF
SSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGTCGTHKYQQSTEHYGGT
HNYWQGNGYWDPRSAGRPPVTGVAYERIQGQVPDSLTDDREE---EENWDQRSGSHFSSP
SNKFFFH--QKDKGSVQAPEISSNSIKDSLVMSERKD-FSKNFEKNDIKERGPPKKRRQE
LESDSESDGELQARKKVRVEIEQG--ESSVPQHS-ELMGPSCAMDDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECPPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHTQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSAKPSTEVDTDTPKKLIFR
RLKIISENSMDSAVSDVTSELECKDGKEDLD-QLETVT---VEEDEE-----LRSHQLLP
QQLCESKVEREATIEVSKLPTSEPEADTEAEPKD-SNGTKLEETIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VAERGRDAAA
FRDQT-APKTPNRSRERDPDKQSQNNKEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPFDSL--GYNAS
HHPFARYPPGYPMQAYVNPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
S--------LAAPPSVPVVPHVAASVEVS----SSQYVAQNE-SVVHQDSNV-PVMPVQA
PGPVQGQNYNVWDSNQ-QSV-SVQ-QQYSPAQSQTTMYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYTQPSL-QYVQGQQIFTAHPQGVVVQPTGAVTSIVAPGQPQSLQPPEVVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

-----------------------------------------------------------A
KIENVQKTGFIKGSVFKGVASSRFLPRGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTP---GVPLQVDSTPKIKMDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTARPLLATTTAVASPPSTA----VQLPA-AIAESTTVDSPPSSPPPP----PPPPQGTT
PSPPAP-VTEPPALSHTSITVPVTA-PVPLPVDVAVRPLK-EPPVTSIPESLEVDTKD--
TVSNSSEEHIAQNLNEQADILLQKEDSHIGKEEEIPDSSK-TSLSSKKTGSKKRSLQSES
TFLGSESDEDSVRTSSSQRSHDIKFSASIEKERDFKKSSASIKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSDRERKRSRS--RSRSDRGSRNSLPYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDSRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
S-SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAMKRCCSPPNELGFRRGS
-SYSKHDN-SASRYKSTPSK-PIPKSDKFKSSFCCTELS-EIK-QSHSSSLQTPCSKGSE
LRMINKIPEREKTGSPSPSSQLNDSPTFKKLDE----SSVLKS-EFIGRDSHDSIKELDS
LSKVKNDQLRSFCPT--ELNVNGSPGA-ESDLATFCTSKTDAVLTTSDDSVTGSELSP--
----LVKT---GRLSSSRFQN--RCKEKYLDDTCMQHSKLES-PFREIEPLVSPHPDKLM
SL----PLRTVDCS-----KTVIKE-PVDM-RVSCCKTKDAETYCTSNDN-NPALCYSEA
E-NIEPSIMKISSNSFMN--VHLESKPVVCDNRNLTE-HSKF-ACEEYK--QSVGSSSLT
TVNHFDDLYQPLGCSVIASSLQSLPSVMKVDRLTLL----QCGENTPPVLDAVLKSKKST
EFLKHAGKETIIEVASGL-LPDSGKGFASWENRHNNGLSGKC----LQEAQEEGNSMLPD
RRGRT--------EICLYEEGERGHAHTSDDSEVVFSSCDLNLTTEDSDS-VT--YTLKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLEPRKHSYEEKFESI-ASKACLQTEKF
F-LHKGTEKNSEISFTQSSRKQVDNH---LPEISHPQSDGVDSTSHTDVKSDPLG-HPNS
EET------IKAKISSREQEELPVYSSDDFEDVPNKSWQQTTFINRPD-SRLGKTE-LGF
SSSSDISRMDGLHSSEELRNLGWDFAQQEKPTTTYQQPDSSYGACGGHKYQQSAEHYGGT
RNYWQGNGYWDPRSAGRSPGTGVMYDRIQGQVPDSLTDDREE---EENWDQRGGSHFSSQ
SNKFHLSL-QKDKGSVQAPEISSNSIKDSLTMNEKKD-FLKNLDKNDIKDRGPPKKRRQE
LESDSESDGELQDRKKVRMEIDEG--GTSVLPGS-ALIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKEERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDECCDILAHSNLKFL-G-LNDSLASASQWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELSDGQES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTDADTDTPKKLIFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LESQQLLL
QQLPESKIDNEITMEASKLPVSEPEADTEIELKE-SNGAKLDEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVG
FRDQTAAPKTPNRSRERDPDKQSQN-KEKRKRRGSLSPPASAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHTQPLVGHSTE
S--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
SGPVQGQNYSVWDSGQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQPLQPLSLLVSWPGP
VWNPPPSAHVAGTITTPKSFEVSVNYDATVLYLGVCTKQTQWDPPTWESPGDDATLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

---------------------------------------------------KILRLAYGA
KIESVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAL-SQVDSTPKIKVDIGDTAATTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLTTTSAVTSPSPST----VQIPA-VIAESTTVDSPPSSPPP----PPPPPQATA
PSSPAP-ITEPVCSPHAPVKVPTAA-PLSLPVEVAVRTLK-ELPTTLVQESLEADSKQD-
IISNSVEEHIIQNPNDQVDTPSQKEDSHIGKEEEIPDSSK-TSLSSKKSGSKKKYLQFEG
TFLGSESDEDSVRTSSSQRSHDLKVSASIEKERDIKKNSAPLKNEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSERGSRASLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRGRESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEIERRGKYSSKLERESKRTSESEAIKRCCSPPSDLGFRWGS
-SYSKHDY-SASRYKSALSK-SISKTDKFKNSFCCAELNEESK-QSHSFSLQTPCSKGSE
LRTISKIPEREKTGSPSPSNRLNDSPTLKKLDE----SPIFKS-ELIGHDSHDSIKELDS
LSKVKNDKLRNFCPI--ELNINGSPGA-ESDV-VFCTSKTDAVLMTSDDSVTGSEVSP--
----LVRA---CMSSSNGFQNI-RCKEKDSEDTCIQH-KSQS-PFKETEPLVLPRSD-NM
SL----PVMTTDYS-----KTVVKE-PIDT-RVSCCKTKDSDRYYTANEN-NLSL----S
E-NTEPSVTKISSNSLMN--VHLESKTVACDKRNLTDQHSKF-TCGEYR--QSVGSTSSA
SVNHLDDLYEPIGSSGIASSLQSLPPGTK------------HDDNTSPVLDGMLKSRKST
EILKHTGKEKRLDIDSG--FPDSGKAFASWENRHNNGLSGKC----LQEAQEEGNSILLD
RRGRP--------EIPLD-EGRRGHTHISDDSEVVLSSCDLNLTMEDNDS-GT--YTLKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSNQSYKHYSDHWEDERLESRRHLYEERFENI-ASKGCLQTEKF
F-FHKGTEKNLEISFMQSGRKQVDNH---LPEIAHSQNDGVDSTSHTDVKSDLLG-HSNS
EEI------IKTRTSSRQQEELPVYSSDDFEDIPSKSRQQTTFPNRPD-SRLGKTE-F-F
S-SCDISHMDGLYSSEELRNLEWDFSQQEKPTTTYQQPDSSYGACGAHKYQQSAEQYGGN
RNYWQGNGYWDPRSAGRPPGSGITYDRIQGQVPDSLTDDHEE---EENWDQRGESHFISQ
SNKFLLSL-QKDKGSVQAPEISSNSVRDSVAINERKD-FSKNLEKSDIKDRGPPKKRRQE
LESDSESDGELQDRKKVRVDIEQG--ETFVAPGS-ELIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECAPLSKEERAQGEVACGEDCLNRLLMI
ECSSRCPNGDFCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRET---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPVIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVT---VEEEEE-----IQSQQPFP
EQLSESKVESETTVEASKLPTLESEADTEIEPKE-SSSTKLEEPLAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VTERGRDAVG
LRDQTAAPKTPNRSRERDPDRQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVMPVPT
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCSSVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTATVTTIVTPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTSSKKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKIGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

----------------------------------------------------------QS
KTETVQKAGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLA
GLGNEKQNETQNSPAVPLQTDFNPKIKMDLGDATGSAEESSPPKPKVELGKIHFKKHLLS
VTTKPLPPAAAATLLPPPPALAPV---TEPV---AAAADFPSAPPP----PPTASPAAPM
P------VPAAAALPQLPVTLMSTL--LLSPPAEAEVPASKELCHAVTKEAPELDLKQE-
VVSHGLEEHVTQHVAEQVEVTPQKEDSHIGKDDEVSESSKGASLCSRKQGSKRKFSQSDG
TLLGSESDEDSVRTSSSQRSHEQKIS-SAEKERDPRKSSSSLRGEEL-KSSSRSRSDRDE
KYSSYSKSERDSR----------------XHSRSRSDRSSRTSSSYSRSERSHYYESDRR
YHRS-SPYRERTRYSRSYADSRGRESSDSEDEYRRTHS-RSSDSRRTSSHS-SSYRESRT
---SYSKSDRDSKVESSHADMERRGKSSSKADRDSKRTSESEVTKRC-SPLNELGYRKGT
SHSKPDSNVNSSRYKSTPSKTPAPKPDKFKSSFCCTESVEEIKQQSNSLDLETSCLKSNE
IRVSI-AKRFEREKTLSPLNQLNDSPAFKNTDESKAAFPHSGSEELAGNECRDSVKEQET
LVRVKHEQLRTCFPI--EMNINGSPEGSSDDLAAPSASKAEDVAVSSDDSLCRLEASH--
----IGRTSNSYPLPSNGFESTYIPKEHEPDDSHIQSSECSS-LFREEEALVLEQQ----
SEAMPSPVVNVDHS-----KIAVKKLDDQA--APCDKTKEPVFCYVSDDA-APSLHHSEV
EIEVEPADVKVTSEAFLD--LHVEPQTVTCDYESTEDPNSKS-ACEEEQYHINPPH----
------QAGLAVDSSSRDSAQDCCSPGIRQDCPVVTQ---HLEENIPSEGDRAPPS----
----CSGTGEVLELDARHVDLNSTQ---SLKDEHSYYSQVPLERCSREEAVEE--MAVTT
ERVGPDDLKEQSQGTSAEDDGGNEPLVASAFPDASFPSCDVVVGADVSRA-SGGAFWLVC
GCNGARALRFLSLQPSPHFLTAGRGHRAALGGGGELPCVCAFPTG-EPLPTSRFYCCVPR
SGSPSSLQDQGAPCKCVCSGAHGCLAPGWKEGSTRYRHPVLMCRAGNGTVGKDSLGLDSL
V-LVLGVLA-------RHNCEVGEKIRSGHRNPVXPQSDGVDSTSQADLAVDSQGKPNPD
ERT-LNELMSISRPLGRQ-EEQPFCVPESFEGTDES-CHQMSFS-KPD-SWQGSGG-LHQ
SGLGDCSREDGFHPREGMGGVSWELQ-AEKPSSTYQQPDSSFGVYSGYVYQPGTGAYSSS
QNCWQGNGYWDVRSAGRP--AGGSYERVQGQVPDSLTEDHEEYE-DDRWDDECKAGFPSP
SSKFHTP-EQKETGSVQAHEISSNSSKEPVSGAEKKE-EVKSLEKNDVKERGPPKKRRQE
LESDSESDVDSRERKKVKVEGEQ----EVAPQD-SSMVGRPCIMDDFRDPQRWKEFAKQG
KMPCYFDLIEENVYLTERKKSKSHRDIKRMLCECPPLSKEERAQGEVACGEDCLNRLLMI
ECSSRCPNGDFCSNRRFQKKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-CHGLSLLWIWMTELGDSRGSTANNLKLQLEIMKTLELLPIPTKNMLEESK
VLPIIQRWAQTKSAIPQLSEGDGYSSENTSRAHTPLNTPELSAKQSAEGDTDTPKKLVFR
RLKIISENSMDSAISDTTSELEGKEGKEDLD-QLEVPPTEVSE---EQQPQ---------
---QEVKTATDPPVESSKPQ--ELEAEPEAEVKE-SNGTKLEEPITMETPSQDEEEGVSD
VESERSQEQTDKIVDVSDLATRLLDSWKDLKEVYRIPKKSQAEKESS---AADRGREAAG
LRDQTPTPKNPVLSRT-DPEWQSLS-KEKKRRRDSLSPPASAYERGTKRPEDRQVGPCQ-
G-SEQRCKGVFSVSLFVKRR----NILHGSCFRETLNHIKGSTKESPLQKEQLLVSQPCQ
HPFFLL-VGKFEMSALKED------------------------VSRSFGKLQPTPGIPSS
PRGAAFSLSLPQFSLRRLTAEPHFPLSVLPRQLPPINVCTSVWSTGRAHG----SVCLGL
CLQWEGCRGSAWHSSEGD-V--HLLKQWYPACLRAPCC----FCPHISGFCSSPYSQTTP
PIVQSYAQPGL-QYIQGQQIYTAHPQGVIVQPPPAVTTIVAAGQPQPIQQPELVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDP PTWDSPGDDASLEHEA
EMDLGTPTYDENPMKSS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAIYKPK--------EDTDLE

---------------------------------------M---L---SWLDGNREEENEA
KIENVQKTGFFKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAGPLQVDLTPKIKMDVGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLTTATAVVSPPPPV----VPLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
PS-PAP-VTEPVALPHTPIPVLMTA-----PVDVAVRTLK-EPPVTTVPESSDVDTKQD-
AVSNSSEEHITQNLNEQADTPSQKEDSHIGKEEEIPDSSK-SNLGSKKTGSKKKSSQSEG
TFLASESDEDSVRTSSSQRSHDLKFSASIEKERDSKKSLAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERARYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-FSYRDLRT
S-SSYSKSDRDCKTESSYLEMEKRGKYSSKVERESKRTSENEAMKRCCSPPNELGFRRGS
-SYSKHDN-SASRYKSALSK-SVSKSDKFKNSFCCTELNEEIR-SSHSFNLQAPCSKGSE
LRMISKIPEREKTGSPSPSNRLNDSPTFKKLDE----SLIFKS-EFIGHDSHDSIKELDS
LSKVKNDQLRSYCPI--ELNINGSPGA-ESDLATFCTSKTDTVLMSSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNINRCKEKDSDNTCMLRSKSGS-PFRETEPTVSPHQDKLM
SL----PVTTIDYS-----KTVIKE-PVDM-AVSCCKTKDSDLYCTSNDN-NPSLRHSEA
E-KIEPSVMKISSNSFMN--VHLKSKTVICDDRNLTDQHSKF-AREEYK--QSVGSTSSA
SVNHFDDIYQPIESSGVASSLQSLPPGVKVDSLTLL----QCGENASPVLDAVLKSK-ST
EFVKHAEKETIIEVGSD--LPDSGRGFASWENRHNNGLSGKC----VQEAQEEGSSIVLE
RRGRS--------EISLDEEGGRGHAHTSDDSEVVFSSCDLNLTMEDSDG-IT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSFPRNRLQSVVVV
PKNSTLPTEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKYDSV-ASKPCSQTEKF
F-HHKGTEKNPEISFTHPSRKQIDNH---LSEIVHPQSDGVDSTSHTDVKSDFLG-HPNS
EET------AKAKIASRQQEELPVYSSDDFEDIPNKSRQQTIFPNRPD-SRLGKTE-LSF
SSSCEISRVDGFRSSEELRNLGWEFSQQEKPTTTYQQPDSSYGACGGHKYQQSAEHYGGT
RNYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EDSWDQCAGSHFSSQ
SSKFFLSL-QKDKGSVQAPEISSNSIKDSLAVNEKKD-LSKNLEKNDMKDRGPPKKRRPE
LESDSESDGELQDRKKVRVAVEQG--ETALPPGS-ALVGPSCVMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECAPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAIPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLEHVP---VEDEEE-----LQSQQLLT
QQLPESKVESEIAMEASKLPISEPEADAEIEPKE-GNGTKLEETIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-TVLPVPA
PGPVQGQNYGVWDSNQQSV--SVP-QQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTAIVTPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLPP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIEHVQKTGFIKGPIFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALTNEKQNDTPNSPGTPLQVDSNPKIKMEIGDTLSTTEDSSPPKSRVELGRIHFKKHLLH
VTSRPLLAATTAVASLPPPT----VLSPA-VIAEST-TDSPPSSPPPP----PPPPQATT
PSSPAP-VSEPVAMPQTPGTVLMAA-PVPLPVDVAVRTQK-EPPVKTVPEPLEEDIKQD-
SVSNSLGEHITQNVKEQVDNSLQKEDSHIGKEEEIPDSSK-ISLSSKRTGSKKKSLQFEG
TF-GSESDEDSVRTSSSQRSHDLKFS-SIEKERDFKKCSAPLKGEDLG-KS-RSKTERDD
KYFSYSKLERDTRYISSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHFYDSDRR
YHRS-SPYRERTRYSRPYIDNRARESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
S-SSYSKFDRDCKTETPYLEMERRGKYSSKLERDSKRTSDHEAIKRC-SPPSELGLRRGS
-SYAKHDN-SASRYKSALSK-PISKSDKFKNSFCCTELNEERK-QSHSFSLQTPCSKANE
LRTSNKTSEREKTGSPSPSNQLNDSPTLKKLDE----SPV-NS-ELIGHDSHDSIKELDS
LSKGKNDQL-SFCPI--ELNVNGSPGT-ESDVVTFCTSKTHAILMTSGE--SGSEVSP--
----LVKT---CMLSSNGFQNISRCKEKDLDDNCMQHSKTKS-PFREIEPLGLPL-----
---MSLPVKTIDYS-----KI-VKE-PVD--KVSCCKTKDLDRYCAVTE--NNSLCYPEA
E-NIESSVSKISSNSFVN--VHLETKTVICDNRDLTD-CSKF-TCEEFN--QS---TSSA
SANHFDDLYEPIGSSDIVSSFQSLPPGIKY-------------ENTSPVLDAALKSKKSS
EFLNYTEKETEVDS---A-FPDSGKGFVSWENRHNNGLSEQC----FQEAQEEGNSVLSD
RRGRP--------EISLDEEEQRGHTHTSDDSEVIFSSYDLNLTMEDSDG-IT--YTLKC
DSSGPVP-E---IISSVHEDFSASSESSSD-----ESDSEDSESDDSSIPRNRLQSVVVV
PKNSTLPMEEMSPCSSRSSQSYRHYSDHWEEERLESRRHSYEEKFESV-KG---SQNEKF
F-LHKGTEKNPETSYTQFNRKQVDNH---LPEITH-QSDGVDSTSHTDMKSDPPG-HLIS
EEK------VKAKPSRLQ--DLTMYS-DDFEDIPNKSRQH-IFSSRPDSSRLGKTE-LNF
T-SYDMSCMDGLHSSEELRNLGWDFSQQERPSTTYQQPDSSYGACGADKYQHSAEQYGGT
SNYWQDNGYWDPRSAGRPPGTGIAYDRIQGQVPDSLTDDRE----EESWDQQGGSHFSNQ
SSKFLSL--LKDKGSVQTHEISSNSIKDSLTVNERKD-FSKNLEKNEIKDKGPLKKRRQE
LESDSESDSELHDRKKVRMETEHG--ETSVPTHS-ELIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSSNCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQNLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKIAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEVDTDTPKKLMFR
RLKIISENSMDSAISDVTSELECKDGKEDLD-QLENIT---VEEEEE-------ELQLPS
QQLPESKVENETTIEASKLPTSEPEADTEIEPKD-GSCTKLEETIVEETPSQDEEEGVSD
VESERSQEHPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKESA---VTERGRDAVA
IRDQSTAPKTPNRSRERDPDKQTQH-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAA
HHAFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
S--------LAAPPSVPVVPHVAAPVEVS----SSQYVAQNE-NVVHQDSSV-AVMPVPA
PGPVQGQNYSVWDSSQQPV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQGYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYRPK--------EDTELE

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
---------------------EKRGRYSSKLERESRRTSENEVVKRC-SPSNDLGFRRGS
-SYSKHDN-SASRYKAAPSK-PIPKSDKFKNSFCCTELHEGIK-QSHSFSLQTPCSKGSE
LRMINKIPEREKTRSPSPSNQLNDSPTFKKLDE----SLIFKS-EFIGHD---SIKELDS
LSKGKHDQLRTYCPV--ELNINGSPGA-ESDLATFCTSKTETVLMSSDDSVTGSEVSP--
----LIKA---CMRSSNGFQNISRCKEKDLDATCMQHSKSES-PFRETEPPVSPHQDKLM
TL----PVKVIDYS-----KTVVKE-PVDM-RVSRCKTKDSDIYYTSNDS-NLSLCHSEA
E-NTDPSVTKISSNSFMN--VHLESKTVICDNRNLTDQNSKF-ACEEYK--QSVGSTSSA
SVNHFDDLCQPVGSSSIASPLQSFPPGIKMD------------KNTSPALDAVLMSKTST
EFLKHAGEETIVEVGSR--LPDSRRGFSSWENRHNNGLSGKC----LQETQEEGNSLLPD
RRGRP--------EISLD-EGGRGHAHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTIHGDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSIVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFEVI-ANKTCPQTEKF
F-LHKGAEKNSDISFAQSSRKQVDNH---LSEMAHPQSDGVDSTSHTDVKSDPLG-HPNS
EEI------VKVKIASRQQEELPVYSSDDFEDVPNKSRQQTTYPHRPD-SRLGKTE-LSF
SSSCEISLVDGFHSSEELRNLGWDFSQPEKPTTTYQQPDSSYGACGGHKYQQSAEQYGGT
HSYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EENWDQRGGSHFSSQ
SNKFLQSIQQKDRGSVQAPEISSNSIKDSLAVNEKKD-LTKNLEKNDMKDRGPLKKRRPE
LESDSESDGELQDRKKVRMEVELG--ETAVPSGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAARDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPVIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSMEADIETPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENIP---VEEEEE-----LQPQQLLI
QQLSESRVDGEAAVEVSKLPMSEPEADTEIEPKE-GNGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---IIERGKDAVG
FRDQTAAPKTPNRSRERDPDKQIQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--AYNAA
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSAE
P--------LAAPPPVPVVPHVTTPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYGVWDSNQQSVS-SVQ-QQYSPAQSQAAMYYPGQTCPAVYG-VAAPYSQSTP
PIVQSYAQSSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQQQPLQPPEVVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLDHEA
EMDLGTPTYDENPMKVS-------------------------------------------
------------------------------------------------------------
-----------------------

------------MKQLPPQQ------P-PLK---MGDFYD---P--EH--PTPEEEENEA
KIESVQKTSFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLS
VLGNEKQNDTPNSPAL-SQVDSTPKIKVDVGDTLATIEESSPPKSRVELGKIHFKKHLLH
VTSRPLLSTTSAVASPSPPT----VQIPA-VIAESTTVDSPPSSPPPPPPPPPPPPQATA
PSSPAP-VTEPVSSPHIPVTALTTA-PVSLPVDVAVRTLK-EPPVTLVQESLEADTKQD-
IISNSSEEHIIQNLNDQADIPSQKEDSHIGKE-ELPDSSK-ISLSSKKSGSRKKYSQFEG
TFLGSESDEDSVRTSSSQRSHDLKISASTEKERDIKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRGSRASLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRGRESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKAETSYLEIERRGKYSSKLERDSKRTSENEAIKRCCSPPSDLGFRWGS
-SYSKHDY-SVSRYKPALSK-SMSKSDKFKNSFCCTELNEESK-QSHSFSLQTPCSKGSE
LRTVSKIPEREKTRSPSPSNQLNDSPTFKKLDE----SPIFKS-EFIGHDSHDSIKELDS
--KVKNDKLRNFCPI--ELNINGSPGA-ESDM-TFCTSKTDTVLMTSDDSVTGSEVSP--
----LVKV---CMSSSNGFQNISRCKEKDLEDTCMQHNKSQS-PFKEAEPLVLTRNNSIT
SL----PVTTTDYS-----KTVVKE-QVDK-RVSGCKTKDSDRYCTANES-NSSLCYSEA
E-NTELSVKKISSNSFMN--VHLESKTVVCDKRNLTDQHSKF-TCGGYR--QSVGGTNSA
SVNHLDDLYEPIGSSDIASSLQSLPAGIKVDNLTLL----QCGENTSLGLDGALKSKKST
EVLKNARKEKILDVDSG--FPESGKAFASWENRPNNALSGKC----LQEAQEEGDSILHD
RRGRP--------EISLDEEERRGHAHTSDDSEVVLSSCDLNLTMEDSDG-IT--YTLKC
DSSGHAP-E---IVSTVHEDYSSSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDHWEDERLESRRYSYEEKCENI-ANKGCLHAEKF
--FHKGTEKNLEISFMQPSRKQVDNH---LPEITYSQNDGVDSTSHSDVKSDHLG-HSST
EEI------IKAKTFSRQQEELPVYS-DDFEDTPSKSRQQTTFPNRPD-SRHGKTE-LNF
S-SCDISHIDGLHSSEEHRNLGWDFSQQEKPTTTYQQPDSSYGACGTHKYQQNAEQYGGH
CNYWQGNGYWDPRSAGRPPGSGVTYDRIQGQVPDSLTDDREE---EENWDQQGESYFVSQ
SNKFLLSF-QKDKESVQAPEISSNSVRDSVAVNERKD-FSKNLEKSDIKDRGPPKKRRQE
LESDSESDGDLQDRKKVRVDVEQG--ETSVVPGS-ELIGPSCVMDDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTDTDADTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVT---VEEEEE-----IQSQQPFS
EQLPEPKVESETTVEASKLPTLEPEGDAEIEPKD-SISTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---ATERGRDAVG
LRDQTTAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVMPVPT
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQTTIYYQGQTCPSVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFAAHPQGVVVQPTAAVTTIVTPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLPSQ-------P-PPK---MGDFYD---PEH----PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALSNEKQSDSPNSPATTLLVDSNPKVKMDTGDTFPTTEESSPPKSRVELGRIHFKKHLLH
VTSRPQLATATAVASPPPPT----VQLPA-VIAES-TVDSPSSSPPPP----PPPPQATS
PSPPAP-ISEPVALPHPPVTVLMTAP---------VDRVQKEPPVKIVPESLEVDMKQD-
IVSNSLEEHTIQTLKEQADNPLQREDSHIGKEEEVSDGSK-ISLSSKKGSSKKKSSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIEKERDFKKSSAPSKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERDRRRSRS--RSRSDRVSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEDEYKKSYLRRT------SSH---SYRDLRT
S-SSYSKFDRDCKTETSYLEIERRGKYSSKLERESKRTSEHESIKRCCSSPTELGFRRGS
-SYSKHDN-SASRYKSALSK-PVSKSDKFKNSFCCAELNEESK-QSHSFSLQTPCSKGSE
LRTINKISEREKTGSPSPSNQLNDSPTFKKLDE----SPILKT-EFIGHDSLDNIKELES
LSKVKNDQL-SFCSI--ELNINGSPET-ESDMATFCASKTDAISMTSDDSVTGSEVSP--
----LIKA---CMLSSNGFQNIDRCKEKDSDDSCRQHSKSKS-PFRETEPSLSPHHDKLM
SS----PGKTVEYS-----KTSIKE-SIDK-IRSCYKTKDSGRCCSPVEN-------SEA
E-NIEPSVMKISSNSFMN--VHLESKTVICDNREPTDQHSKF-ACDEYK--QSIGTTSSA
SPNHFDDLYESIGSSGIVSSFQSLPPGI------------KCDENIPSVLDAMQ-SKKST
EFLKYVGKETEVG--S-A-LPDSGKGFASWENRHNNVLSGQS----LQEAQEEENSILHD
RRERA--------EI-LDEEEGRGHTHTSDDSEVVFS-YGLNLTMEDSDG-IT--YTLKC
DSSGNAP-E---IISTIHEDYSGSSGSSSD-----ESDSEGTESDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSHSYRHYSDHWEDERLESRRHSYEDKFESM-ASKGCPQTEKF
F-LHKGTERNLETSYSQFSRK-VDNH---LPEIAHSQSDGVDSTSHTDLKSDPLG-HLNS
EDT------VRAKTSRSQ--ELPLYS-DDFEDIPNKSRQQIIFSNRPDSSRLGKTE-MNF
SSSCDISRMDGLHSSEELRNVGWDFSQQERPTSTYQQPDSSYGACGTHKYQQNAEHFGGT
HNYWQGNGYWDPRSAGRPPGTGVAYDRIQGQVPDSLTDDREE---EENWDQRSGSHFSGQ
SNKFFFH--PKDKGSVQAPEISSNSTKDSLVTNERKD-FSKNFEKNDIKERGPPKKRRQE
LESDSESDSELQARKKVRVESEPG--ETSALLHS-GLMGPSCAMDDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECAPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIATKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSIKLSTEVDTETPKKLMFR
RLKIISENSMDSAISDVTSELECKDGKEDLD-QLETVT---VEDDDD-----LQSQQLLA
QQLCESKVESEASIEGNKLPASEPEADVEAELKE-SSGTKLEETIAEETQSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---GTERGRDATA
FRDQT-IPKTPNRSRERDPDKPAQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLQNLGMTSPLPFDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSIDPVCSPAP-----YDHAQPLVGHPTE
S--------LAAPPSVPVVPHVAASVEVS----SSQYVAQNE-SVVHQDSNV-PVMPVQA
PGPVQGQNYNVWDSNQ-QSV-SVQ-QQYSPAQSQATIYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAASVTTIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
----VQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAL-SQGDSTPKIKVDIGDTLATTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTSAVASPSPPP----VQLPA-VIPESTTIDSPPSSPPPP----PPPPQATT
PSSPAP-ITEPVASPHTPVTVLTTA-PLSLPVDVAVRTLK-EPPVTLVKESLEVDTKQD-
IISNNSEEHITHNLNDQVDSPSPKEDSHIGKEEDIPDSSK-ISLSSKKPVSKKKYSQFEG
SFFGSESDEDSVRTSSSQRSHDLKISASIEKERDIKKSSAPLKSEDLG-KSSRSKTERED
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRGSRASLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRGRESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLDIERRGKYSSKLERESKRTSENEAIKRCCSPPSDLGFRWGS
-SYSKHDY-SASRYKSALSK-SIPKSDKFKNSFCCTELNEESK-QSHSSSLQTPCSKGSE
LRTVSKIPEREKTGSPSASNRLNDSPTFKKLDE----SPIFKS-EFIGRDSHDSIKELDS
LSKVKNDKLKNFCPI--ELNINGSPGA-ESDVTTFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CISSSNGFQSISRCKEKDL-DTCMQHSKSQS-PFKETEPLVSPCSD-NM
SL----PVMTTDYS-----KT-EKE-PVDM-RVSCCKTKDSDRYCTANES-NPSL----S
E-TVEPSVTKISSNSFKN--VHLESKTVVCDKRNLTDQHSKF-TCEEYK--QSVGSTSSA
SVNHLDDLYEPIGSSSIGSSLQSLPPGIK---------------NTSPVLDGVLKSKKST
EVLKHTGKEKIVDVGSG--FSNSGKAFASWENRHNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLD-EGVRGHAHTSDDSEVVLSSCDLNLTVEDD--GVT--YTLKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDHWEDERLELRRYSYEEKFENI-TSKGCPQTEKF
F-FHKGTEKNPEISFIQSSRKQVDNH---LPEIAHSQSDGVDSTSHTDMKSDLLG-HSNS
EEI------TKAKTSFRQQDELPVYS-DDFEDIPSKSRQQTTFPNRPD-SRLGKTE-LNF
S-SCDISCMDGLHSSEELRNLGWNFSQQEKPTTTYQQPDSSYGVCGAHRYQQSAEQYGGN
RNYWQGNGYWDPRSAGRPPGSGVAYDRIQGQVPDSLTDDREE---EENWDQRGESHFLSQ
SNKFLLSL-QKDKGSVQAPEISSNSVRDSLAVNERKD-FSKNLEKSDIKDRGPLKKRRQE
LESDSESDGELQDRKKVRVDIEQG--GTSVPPGS-ELIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTTAPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAVSDAASELEGKDGKEDLD-QLENVT---VEEEEE-----MQSRQLFP
EQLPEFKVESETTVEASKLPTLEPEADAEMEPKE-SSGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VTERGRDAVG
LRDQTAAPKTPNRSRERDLDKQTQS-KEKRKRRGSLSPPSSAYERGTKRSDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX-----XXXXXXXXXXXX-
X--------XXX---XXXXXXXXXXXXX-----XXXXXXXXX-XXXXXXXXX-XXXXXXX
XXXXXXXXXXXXXXXXXXXV-SVQ-QQYSPAQSQATIYYQGQTCPSVYG-VT-SYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVTPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

-------------------C------T-HFG---LPKFWD---Y--RC------EPPHPA
KIENVQKTGFIKGPIFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPAHA----VPLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
PSSPAP-VTEPVPLPHTPITVLMAA-PVPLPVDVAVRALK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQNLNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKYSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEDYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRALENEAMKRCCSPPNELGFRRGL
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGNE
LRMINKNPEREKPGSPSPSNRLNDSPTFKKLDE----LPIFKS-EFIAHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKADAVLMTSDDSVTGSEVSP--
----LVKA---CVLSSNGFQNISRCKGNDLDDTCMLHNKSES-PFRETEPLVSPHQDKFT
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDS-NPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKTVISDSRNLTD-HSKF-ACEEYK--QSVGSTSSA
SVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLL----KCGENISPGLDAVLKSKKSS
EFLKRAGKETIVEVGSD--LPDSGKGFASREKRHKNGLSGKC----LQEAQEEGNSILPV
RRGRP--------EISLDE-GERGCMHTSDDSEVVF-SCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSHSYRHYSDHWEDERLESRRHSYEEKFESI-ASKACLQTDKF
F-LHKGTEKNPEISFTQSSRKQVDNH---LPELSHPQSDGVDSTSHTDVKSDHLG-HPNS
EET------VKAKISCRQ-QELPIYS-SDFEDVPSKSWQQTTFPNRPD-SRLGKTE-LSF
SSSCEISHVDGLHSSEELRNLGWDFSQ-EKPTTTYQQPDSSYGACGGHKYQQSAEQYGGT
RDYWQGNGYWDPRS-GR-PGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDVSHFSDQ
SNKFLISL-QKDKGSVQAPEISSNSIKDTVAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVQQE--ETSLPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRET---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEVDTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-PLENVP---VEEEEE-----LQSQQLLP
QQLPECKVDSETSVDASKLPTSEPEADAEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVA
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPASAYERGSKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSAE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVTQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMIVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLPP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPIFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDMPNSPAVPLQVDSTPKIKTDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLTTTTAVTSPPPPI----LPLPA-VVAESTTVDSPPSSPPPP----PPPPQAPA
PSSPAP-ITEPVALPHTPVTVLMTA-----PVNVAARALK-EPPVIIVPESSEVDTKPY-
TVSNSSEEHITHNLSEQADIPSQKEDSHIGKEEEMPDSSK-SSLGSKKTGSRKKSSQSEG
TFLGSESDEDSIRTSSSQKSHDLKYSANIEKERDSKKNLAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRSERERRRSRS--RSRSERGSRSSLSYSRSERSHYYDSDRR
YHRS-SPYRERARYSRLYTDNRARESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
S-SSYSKSDRDCKTESSYLEMEKRGKYSSKLERESKRTSENESVKRCCSPPNELGFRRGS
-SYSKHDT-SASRYKSAPSR-PIPKTDKFKNSFCCTELNEEIR-QSHSFGLQTPCSKGSE
LRMISKVPEKEKTESPSPSNRLNDSPTFKKLDE----SPIFKS-EFIGRDSHDSIKELDS
LCKVKNDQLKSYCST--ELNVNGSPGV-ESDLATFCTSKTDTVLMSSDDSVTGLEVSP--
----LVKA---CMISSNGFQNINRCKEK--DNTCIQHTRSGS-PFRETESLLLPHQDKLM
CL----PV---DYS-----NTVVKE-PVDM-RVSCCKTKDSDIYCTSNDS-RPSLCHSEA
E-NTEPLVTKISSNSFMD--MHLKSKTVICDNRNLTDQHSKF-ACGEYK--QSVGSTSSA
SINHFDNLYQSAGSSCIASSLQTLPPGIKVDSLPLL----QCGDNTSPVLDAVLKSK-ST
EFLKHAEKETSIEVDGG--LPDSGRGFASWENRHNNGLSGKC----VQERQEEGNSILPD
RKGRP--------EVSLDEEGGRGHAHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLETRRHSYEEKFESI-TSKSCAQTEKF
F-LHKGTEKNPEISFTHPSRKQVDNH---LPEITHPQSDGVDSTSHTDVKSDSLG-RPNS
EEM------VKAKIASRQQEELPVYSSDDFEDVPNKSRQQATFPKRPD-SRLGKTE-LNF
S-SCEISRVDGFRSSEELRNLGWDFSHQEKPTTTYQQPDSSYGSCGGHKYQQNTEQYGGT
RNYWQGNGYWDPRSAGRPPGTGVVYDQIQGQVPDSLTDDREE---EENWDQHGGSHFSNQ
SNKFFLSL-QKDKGTVQAPEISSNSIKDSLAVNEKKD-LSKNLERNDMKDRGPLKKRRQE
LDSESESDSELQDRKKVRVEVEQG--ETAVPLGS-ALVGPSCVMEDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPVIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADIDTPKKVALR
KLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVH---VEEEEE-----LQSQQLLT
QQLPESKVDSEIAVEGSKLPTSEPEPDTEIEPKE-SNGTKLDEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---ITERGRDAVG
FRDQTVAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHSQPLVGHSTE
A--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-NVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATYIIKDRLVQLSMV-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------LERRGKYSSKLERESKRTSESEAIKRC-SPSNELRFRRGS
-SYSKHDN-STSRYKSASSK-PISKSDKLKNSFCCAELNEGSK-QSHSSSLQSPCSKGNE
LRTGSKIPERERTGSPSPSNQLNDSPTFKKLGE----SPIFKS-ELKAHDSHDSIKELDS
SSEEKNDQLRSFCPS--ELNINGSPGA-ESDLATFCTSKSNAVLITSDDSVTGSEVSS--
----LVKT---CMLSSNGFQNISRCKEKGLDDTSMELSKSES-PFRETELMLSPHHDKLI
PL----PVMTLDYS-----KTAGKE-PVEV-RVSCCKTKDSDVYCTTND--SNSLCYSEA
E-NIEPSVMKISSNSFMN--VHLESKTVTCDNRNLTDQYSNF-TVEECK--QNIGSTGSA
SVNEFDDLCESVGSSGIASTFQNLSPGVKADSVTLL----QCGESTSPVLDAALKSKRSI
EVFKHAGKETVVEVGSG--LPDSGKGFTSWENRHNHEISERC----LQETEEEGNSVLPD
RRGKP--------ENCLDEEGGRRYMHTSDDSEVGFSSCNLNLAIEDTDS-AT--CILKC
DSSGHAP-E---IVSTVHEEYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLEPRRHSYEEKFENV-TNKACLPTDKF
F-LHKGTEKNPEISFAQSSRKQVDNH---LPETAHSQSDGVDSTSHTDVKSDVLG-HPNL
EET------VRTKISSRQQEELPVYSSDDFEDGPIKSRQQTIFTNRPD-SRLGRME-LSY
SSSCELSQADGLHSSEELQSLGWDISQQEKPTTTYQQPDSSYGACSGHKYQVTAEQYGAT
RNYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EENWDPRSASHFSSQ
SSKFLLSH-QKDKGSVQAPEISSNSIKDSLPVNDKKD-FPKSLEKNDIKDRGPPKKRRQE
LESDSESDGDLQDRKKVRVEVEQG--QTILPPGS-ELIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGGES---NQKLQEEXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEADTETPRKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENAP---VEEEEE-----LQSQQLLP
QQLPESKVDSETPLEASKLPTSEPDADIEMEPKE-SNGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDTIA
FRDQTTVPKTPNXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPGPVVPHVAAPVEVS----SSQYVTQSD-GVVHQDSNV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--GVQ-QQYSPAQSQATIYYQGQACPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVTPGQPQPLQPPEMVVTSN-L
LELPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
------------------------------------------------------------
---------------------------MDLGDAAGSTEESSPPKPKVELGKIHFKKHLLS
VTTKPPPPAAAATLLPPPPALAPV---TEPV---AAAADFPSAPPP----PPTASPAAPM
P------VPTAAALPQLPVTLMSTL--LLSPPVQAEVPASKEPCHVVPKEALELDPKQD-
VVSHGLEEHLTQHVAEQVEVTPQKEDSHIGKDDEVSDSSKGASLCSRKQSSKRKFSQSDG
TLLGSESDEDSVRTSSSQRSHEQKIS-SAEKERDPRKSSSSLRGEEL-KSSSRSRSDRDE
KYSSYSKSERDSRYSSSRSRSDRERRRSRSHSRSRSDRSSRTSSSYSRSERSHYYESDRR
YHRS-SPYRERTRYSRSYADSRGRESSDSEDEYRRTHS-RSSDSRRTSSH--SSYRESRT
---SYSKSDRDSKVESSHADVERRGKS-SKADRDSKRTSESEVTKRC-SPLNELGYRKGT
SHSKPDSNVNSSRYKSTPSKIPAPKPDKFKSSFCCTESVEEIKQQSNSLDLETSCLKSNE
IRVSI-AKRFEREKTLSPLNQLNDSPTFKKTDESKAAFPHSGSEELASNECHDSVKEQET
LVRVKHEQLRTGFPI--EMNINGSPEGSSDDLAAPSASKAEDVAVSSDDSLCRLEASH--
----VGRTSNSYPLPSNGFESTYTPKEHEPDDSHVQSSECSS-LFKEEEALVLEQQ----
SEAMPLPVVNVDDS-----KISVNNLDDQA--APCDKTKEPVFCYVSDDA-TPSLYHSEV
EIEVEPADVKVTSEPFLD--LHVEPQTVTCDYESTEDPNSKS-ACEVEQYHVNPPH----
------QAGLAVDSSSRDSAQDCSSPRIRQDCPLVTQ---HLEENVPSEGGGALPS----
----CSGTGEVLELDVRHVDLNSAQGKLSLKDEHSYYSQVPLEHCSREEAAEE--MAVTT
ERVGPDDLKEQDQGASAEDDGGNEPLVASAFPDASFPSCDVVVAAEEPEA-VTQA--PTC
DSSGGTS-EF---APAPHDDYSDTAESDSEPGS-DDSDTEDTDSD-DGVPRKRLQSVVVV
PKNSSIAMEDSSPCSSRSSQGARRYSDHWDDERPEPSRPYYEERPEAT-ASNNGLQAESR
C-SPRGMEKSPASS-TELSRKDGEEL---RADACQPQSDGVDSTSQTDLAVDSQGKPNTD
ERM-LNELMSIGRPLGRQ-EEQPFCVPESFESTNES-CHQMSFS-KPD-SWQGSGG-LHQ
SGLGDCSREDGFHSVEGMGGVSWELQ-AEKPSSTYQQPDSSFGVYSGYVYQPGTGAYSSS
QNCWQGNGYWDARSAGRP--AGGNYERVQGQVPDSLTEDHEEYE-DDRWDDECKAGFPSP
SSKFHAP-GQKETGSVQAHEISSNSSKEPVSGTEKKE-EVKALEKNDVKERGPPKKRRQE
LESDSESDADSRERKKVKVEGEQ----EVAPQD-SSMVGRPCIMDDFRDPQRWKEFAKQG
KMPCYFDLIEENVYLTERKKSKSHRDIKRMLCECPPLSKEERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQKKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-CHGLSLLWIWMTELGDSRGSTANNLKLQLEIMKTLELLPIPTKNMLEESK
VLPIIQRWAQTKSAIPQLSEGDGYSSENTSRAHTPLNTPELSAKQSAEGDTDTPKKLVFR
RLKIISENSMDSAISDTTSELEGKEGKEDLD-QLEVAPTEVSE---EQQPQ---------
---QEVKVAVDTPVESSKPQ--ELEAEPEVEVKE-SNGTKLEEPITMETPSQDEEEGVSD
VESERSQEQTDKIVDVSDLAIRLLDCWKDLKEVYRIPKKSQAEKES----SADRGREAAG
LRDQTPTPKNPVLSRT-DPEWQNLS-KEKKRRRDSLSPPASAYERGTKRPEDRYDTPAS-
K-KKVRLKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLQNLGITSPLPYDSM--GYGTP
HHSFIGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDSMCSPAA-----YEHPQPMVGHTVE
P-------TLPTPQPVPVVQHVATPMEVTT----PQYVAQSD-AVVHQEPNV-AVLPVPT
TGPVQGQSYGVWDSSQQT-V--AVQQQYSPAQSQPAIYYQGQTCQTVYG-VTSPYSQTTP
PIVQSYTQPGL-QYIQGQQIYTAHPQGVIVQPPPAVTTIVAAGQPQPIQQPELVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDP PTWDSPGDDASLEHEA
EMDLGTPTYDENPMKSS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAIYKPK--------EDTDLE

----------------------------------------------------------QG
KPETVPRAGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLT
ALGNEKQNETPTPPAVPLPTDFNPKNKLDLGDAAGSAEESSPPKPKVELGKIHFKKHLLN
VTAKPPPA-----------AAAPG---GGGG---GGGG-GGGGGPPPPPPPP--PPASPV
P------VPGATAP---PVTPMPAL--LLSPPGEAEAPVPREPSHALPREASEPDAKRD-
PASRGSEERAAQTAPEQTEITPPKEDSHIGKEDEVSDGSKGAAPCSRRQGAKRKFSQSDG
ALQGSESDEDSVRTSSSQRSHEQKIS-STEKERDARRSSTSLRGDDPGKSSSRSRSDRDE
KYSSYSKSDRDSRYSSSRSRSDRERRRSRSHSRSRSDRSSRTSSSYSRSERSHYYDSDRR
YHRS-SPYRERSRYSRSYADSRARESSDSEDEYRRTHSSRSSDSRRTSSHSSSSYRDSRS
---SYSKSDRDSKVESSHADVDRRGRSSSKADRDSKRTSESEVSKRC-SPLDELGYRKGT
SHSKPDSNVNSSRYKSTPSKAPAPKPDKFKSSFCCTESIEEIKSKSNSLDLETSCVKNNE
IRVSS-VKKLEREKTLSPLNQFNDSPALPKADESKAGLANSKSEELAANEGHDSVKEQET
FLKAKHDPLRACFPT--ESSVNGSPEGQDECLATSSASKAEDVAAPSDHGPGRSEASP--
----ALETSLSYPLPSNGFESTDVSQEQELDESRVQSSECNS-LFQEAEAPEPQQQP---
EETAPLPDVNVDPT-----KTVLKKLDEEVT--PCDKTKEPVFCFISDDA-TPGLYHSEV
EIEVEPADLKVTSETFLD--VQVEPQTVTCDYESTEDSHSRC-AGE--DEHGHPSH----
------RISLAVESSSRDSSQDGCSQRLQSDHPVP-------EESVSSKWDVPPPGV-CQ
E----SEAEEVLELDAQHVDLGSAKGKLSFQNEHSYYSEVPLEHRGRG-AVEE--SAVST
EGAELDEPRVQCPGLSPERDEGNEPLVASAFPDALYPSSDVIITAEDTEM-VTQA--PTC
DSSGNAS-E---FIPAGHDDYSDMGDSDSEGGS-EDSDTEDSDSD-DGTPRKKLQSVVVV
PKNSTIATEENSPGSSR---SSRRFSDHWDDERPEPSRPYYEERSENT-GSKGGGQVESR
C-SPRGMEKSPATS-TELSRKEAEEL---RADPCQAQSDGVDSTSQADLAADSHGKSGTE
ERTVLPDVVAVGRPM----EEQPFCVPESLESTDTS-RHQMGSS-KPD-SRQGQGG-LNQ
SGLGDCSRLDGFRAPGELGAVGWEFSQSEKPSSTYQQPDSSFGVYSGYVYQPGSGAYPSS
QSYWQGNGYWDARAGSRA--SVVSYERIQGQVPDSLTEDHEEFEEDERWDEECKPRFPSP
SGKAQTP-GQKEKGSVQAHEISSNSTKEPVPGGEKKE-EVKTSEKNEVKERGPPKKRRPE
LESDSESDGDSGEKRKGKLEGEQV---EPAPQD-SSMVGRLCIMDDFRDPQRWKEFAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMLCECPPLSKEERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQKKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSSNCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-CHGLSLLWIWMTELGDGRGSTANNLKLQLEIMKTLELLPIPTKNMLEESK
VLPIIQRWAQTKTAVPQLSEGDGYSSENTSRAHTPLNTPELLAKQSVEGDTDTPKKLVFR
RLKIISENSMDSAISDTTSELEGKEGKEDLD-QLEAAPMEVAE---EQQQQQQ-------
-QQQDIKTAVEAPVESS--KPAELEAEPEAEVKE-SNGAKLEEPMAMETPSQDEEEGVSD
VESERSQEQTDKIVDVSDLATRLLDSWKELKEVYRIPKKSQAEKENS----VFPTADR--
GRDQTPTPKNPILSRERDPERQSQS-KERKRRRDSLSPPSSAYERGTKRPEDRYDTPAS-
SKKKVRPKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLQNLGMTSPLPYDSM--GYGTS
HHSFIGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDSMCSPAG-----YEHSQTLVGHAVE
PA-------LSAAQPVPVVQHVATST---MEVATPQYVAQGE-AVAHQEANVAAVLPVAA
AGAVQGQSYGVWDSSQQP-V--AVQQPYSPAQSQPAIYYQGQTCQTVYG-VTSPYSQTTP
PIVQSYAQPGL-QYIQGQQIYTAHPQGVIVQPPTAVTTIVAAGQPQPIQQQELVVSNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDP PTWDSPGDDASLEHEA
EMDLGTPTYDENPMKSS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGILYKPK--------EDTELE

-----------------------------MI---YFLFFC---M--LSWLDDNREEENEA
KIENVPKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPVVPLQVDSTPKVKTDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLTATTAVASLSPPM----APLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
PSSPAP-VTEPVALPHTPVTVLMTA-----PVDVAARALK-EPPVTVVPESSEVDTKQD-
PVSNSSEEHITHSLNEQADIPSQKEDSHIGKEEETPDSSK-SSLGSKRTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSANTDRERDSKKSLATFKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRE-RERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRAYTDSRARESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
S-SSYSKSDRDCKTESSYLEIEKRGKYSSKLERESKRTSESEAMKRCCSPPNELGFRRGS
-SYSKHDN-NASRYKSAPSK-PVSKSDKFKNSFCCTELNEETR-QSHSFSLQTPCSKGSE
LRVISKIPEREKTRSPSPSNRLNDSPTFKKLDG----SPVFKS-EFIGHDSHDSIKEVDS
LCKVKNDQLRSYCPT--ELNINGSPGA-ESDLAAFCTSKHDTVLMSSDDSVTGSEVSP--
----SVKT---CMLSSNGFQNTNRCKEKDLDDTCMKHSKSES-ASRETEPLVSPHQDQLI
SL----PVITIDYS-----KTVVKE-PVEV-RVSCCKTKDSDIYCTSNDN-HTSSCHSGA
E-NTEPLVSKMSSNSFMN--VHLKSKTVICDHGNLTDQRSKF-ACGEYK--QSVGSTSSA
SVNHFDDLYQTPGSSCIASSLQSLPPGMKVNSLTLL----QRGENISPVLDAVLKSK-NS
EFLKHAEKETVIEVGGD--LPDSGRGFASWDSRHNNGLSEKC----VQEAHEEGNSLLPD
RRGRP--------EISLDEEGGRGHTHISDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLTMEETSPCSSRSSQSYRHYSDHWEDERLEPRRHSYEEKFESI-TTKSCPQTEKF
F-FHKAAEKNSEISFIQPSRKQIDNH---LPEIAHPQSDGVDSTSHPDIKSDPLG-HSNS
EET------VKTKIASQQQEELPVYSPDDFEDVSSKSRQQTAFPIRAD-SRLGKTD-SSF
SSSCEISRVDGVRSSEELRNLGWDFSQQEKPTSTYQQPDSSYGACGGHKHQQSAEQCSGV
RSYWQGNGYWDPRLASRPPGAGLVYDRIQGQVPDSLTDDREE---EENWDQRGGSHFSSQ
SSKFFLSL-QKDKGSVQAPEISSNSIKDSLAVNEKKD-LLKNLDRNDMKDRGPLKKRRQE
LESDSESDGELQDRKKVRVEIEQG--ETAVPLGS-ALVGPSCVMEDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAIPQLSEGDGYSSENTSRAHTPLNTPDPSTKLNAEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---IEEEEE-----PQPQQLLV
QQLPEPKVDSDIAAEASKLPASELEADAEIEHKE-SSGAKLDEPIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---ITERGRDAVG
FRDQTVAPKTPNRSRERDPDKQTQI-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAA-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-AVVHQDSSV-TVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQTTIYYQGQACPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------EEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAGPLQVDLTPKIKMDMGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLTTATAVASPPPPI----VPLPA-VIAESTTVDSPPSSPPPP----PPPPQATA
PSPPAP-VTEPVALPHMPIPVLMTA-----PVDVAVRALK-EPPVTTVPESSEVDTKQDA
AVSNSSEEHITQNLNEQVDTPSQKEDSHIGKEEEIPDSSK-SNLGSKKTGSKKKSSQSEG
TFLASESDEDSVRTSSSQRSHDLKFSANIEKERDSKKSLAPLKNEDVG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERARYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-FSYRDLRT
S-SSYSKSDRDCKTESSYLEMEKRGKYSSKLERESKRTSENEGMKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSALSK-SISKSDKFKNSFCCTELNEEIK-TSHSFNLQAPCSKGSE
LRMISKIPEREKTGSPSPSNRLNDSPTFKKLDE----SLIFKS-EFIGHDSHDSIKELDS
LSKVKNDQLRSYCPI--ELNINGSPGA-ESDLATFCTSKTDTVLMSSDDSVTGSEVSP--
----LVKA---CMLPSNGFQNINRCKEKDSDDTCMLHSKSGS-PFREAEPPVSPHQDKLM
SL----PVMKIDYS-----KTIVKE-PVDM-TVSCCKTKDSDIYCTSNDN-SPSLHHSEA
E-KIEPSATQISPNSFMN--VHLKSKTVTYDNRNLTDQRSKF-ACEEYK--QSVGSTSSA
SVNHFDDLYQPIESSGIASSLPSLPPGIKVDSLTLL----QCGENTSPVLDAVLKSK-ST
EFLKHAEKETV-EVGSG--LPDSGKGFASWENRHNNGLSGKC----VQEAQEEGNSILPD
RRGRA--------EISLDEEGGREHAHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESV-ASKPYSQTEKF
F-HHKGTEKNLEISFTQPSRKQIDNH---LSETAHPQSDGVDSTSHTDVKSDFLG-HPNS
EET------AKTKIASRQQEELPVYSSDDFEDVPSKSRQQITFPNRPD-SRLGKTE-LSF
SPSCEISRVDGFRSSEELRSLGWEFSQQEKPTTTYQQPDSSYGACGGHKYQQSAEHYGGT
RNYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EEIWDQRGGSHFSSQ
SNKFFLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKD-LPKNLEKNDMKDRGPPKKRRQE
LESDSESDGELQDRKKVRVAVEPG--EIAVPPGS-ALVGPSCVMEDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDTVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAIPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSIEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPESKVESEITVEASKLPTSEPEADTEIEPKE-GNGTKLEETIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLQTLGMTSPLPYDSL--GYSAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPNMDPVCSPAP-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-TVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKPLPSQQ------P-PPK---MGDFYD---PEH----PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSFTKKTLQNRFLT
ALSNEKQSDSPSSPATPLQVDSNPKVKMDAGDTFPATEESSPPKSRVELGRIHFKKHLLH
VTSRPQLAATTTVASPLPPT----TQLPA-VIAES-MIDSPPSSPPPP----PPPPQASS
PSPPAP-ISEPVALPQPPVTALMTSPPGPLPVDVAVRAQKEPPV-KSVPEFLEVDTKQD-
IVSNSLEEHTVQTLKEQADNLLQKEDSHIGKEEEVSDGSK-ISLSSKKASSKKKSSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIDKEKDFKKSSAPSKSEDLG-KSSRCKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRASRTSLSYSRSERSHYYDSERR
YHRS-SPYRERTRYSRPYPDNRARESSDSEDEYKKTHPRRS------SAH---SYRDLRT
S-SSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSEHETIKRCCSPPNELGFRRGS
-SYSKHDN-STSRYKSALSK-SISKNDKFKNSFCCTELNEENK-QSHSFSLQTPCSKGSE
LRTINKISEREKTGSPTPSNQLNDSPTFKKLDE----SPVLKP-EFIGHDSHESIKELE-
LSKVKNDQLRNFCSI--ELNVNGSPET-EADVATFCTSKTDAISMTSDDSVTGSEVSP--
----LIKA---CMLSSNGFQNVGRCRERDSDDTCRQHNTSKS-PFREMEPLLSPHHDKLM
SL----PVKTVDYP-----KTLIKE-PVDK-RHSCCKTKDSDRYCSPNEN-------SEA
E-NTEPSVMKISSNSFVN--VHLESKTVICDNRELTDQHSEN-TCDEYK--QNIGRTSSA
SLNHFDGLYEPIGSSGI-SSLQSPPSGI------------RCEEDTSPTLDAVQ-SKKGI
DFLKYAQKEADVG--S-A-LPDSGKGCS-WENRHNNVLSGQS----LQEAQEEGNSILHE
RRGRP--------EMPLDED-QRGHTHISDDSEVVFP-YDLNLTMEDSDG-IT--YTLKC
DSSGNAP-E---IVSTVHEDYSGSSASSSD-----DSDSEDTESDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDHWED-GLETRRHAYEEKYE----SKGCSQTEKY
F-LHKGAERNAETCYPQLGRK-ADNH---LPDVAHSQSDGVDSTSQ-------TG-HLNP
EDT------LRAKTSRPQ--ELPVYS-DDFEDLPNKSRQQMIFSNRPDSSRLGKTE-LSF
SSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGTCGTHKYQQSTEHYGGT
HNYWQGNGYWDPRSAGRPSGTGVAYDRIQGQVPDSLTDDREE---EEHWDQRSGSHFSSP
SNKFFFH--QKDKGSVQAPEISSNSIKDSLVMNERKD-FSKNFEKNDIKERGPPKKRRQE
LESDSESDGELQARKKVRVEMEQG--ESSVPQHS-ELMGPSCAMDDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRGS---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSAKPSTEMDTDTPKKLIFR
RLKIISENSMDSAVSDVTSELEGKDGKEDLD-QLEAVT---VEEDEE-----LQSQQLLP
QPLCDSKVESEATIEVSKLPTSEPEADMETEPKD-SNGTKLEETIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VAERGRDAAA
FRDQT-APKTPNRSRERDPDKQSQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPFDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
S--------LAAPPSVPVVPHVAASVEVS----SSQYVAQNE-SVVHQDSNV-PVMPVQA
PGPVQGQNYNVWDSNQ-QSV-SVQ-QQYSPAQSQTTIYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTSIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

----------------------------------------M-----TTCFCS-----IQG
KIENVQKMGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNDKQNDTPNSPAVPLQADFVPKIKMDPADTSTVAEESSPPKPKVELGKIHFKKHLLH
VTSKPLLNAVTPVAASPSLS-----IIPSPVVTESVVAESPPQSPPPP----PSALQVRT
PSPPAP-ISVTTALPQIPTSVPVGTSLQSLPIDVAIRASK-ESLNIVVPESLELDTKQD-
TCSSELLDIVSQNVSEKVDISPQKEDSHIGKEEETPDSSK-SSLCSKKTSSKKKFSQSEG
MFLGSESDEDSVQTSSSQRSHDFKNSASMEKERDSKKSLVTLKGEDLG-KPSRSKTERDD
KHFSYSKLDRDSRYMSSRSRSERERRRSRS--RSRSERGSRTSSSYSRSERSHYYESERR
YHRS-SPYRERPRYSRSYADNRMRESSDSEEEYKKIYSRSS-DSRRTSSHS-SFYRDSRT
--STYSKSDRDSKIESFHMDTEKRGKYSSKPERESKRTSENELMKRCCSPPNEMGCRRGA
-SYSKHDT-NASRNKSVPWK-STQKPDKIKSSFCCTESTEEIKHQSHSLNLQ-TCSKSNE
FKM-VKIPERDKTLCPSSTNRLNDSPTFKKLGE----SPIFKS-EFMGNDSHDSIKESDT
LSKGKHDQLRTYCPM--ELDINGSPGE-GSDLATFCVSKTEDIFTSSDDSINKSEVSP--
----LIKTNKSCVLPSNGFQNVNRSKEKNLDDSFVHHSELNS-SLKEMDPSVPSQQDKFG
SF----PVINVDYS-----KTVKE--SVDL-RVSYCKTKDLGSCNNLDDN-SPCLYQLET
E-TIEPAVIKVIPNTLMNQ--DSEVQSVICDNKNYKTLHSVQPTTEESEQKVRVK---SV
SVNPC-DSNSPVESSSV-ASVCSPTLGVKVDNPPVIQ---HTEGNLPLGVDTVLQNQ-ST
EFLKHPGRE-IIELDEQQINPETRKRIVPWKNRHNSVLPMESLQAEE--VEEVEDVMFHS
GRERAV-----STEGPFNKQEGSRNMFYSGVSEPLFSSCEMSRTVEEGGGSIA--RGPKC
DSSGNTS-E---FVSPNHGDYSDSSQSTSD-----ESDTEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSQSSQVNRHYSDHWEDDRPESS-KPYEERFEGM-MSKNCSQTEKF
S-FSKGADKSPDLPYMEPSRKHMEDL---ELEGAQPQSDGVDSTSQADVASDRIGLKNLE
ERNVSKESLIITKPILRQQEEVPAYSSDGFEGILTKSRQQNNFPNRPD-SRLGKTESDNF
SSSGDFSRVDGFHSAEDLGNLGWDFSQPEKPSTTYQQPDSSYGIYTGYNYQQSTEQYRGT
HNYWQGNGYWDPRL-NRPS--GMMYDRAQGHVPDSLTNDHEE--DEENWDDPRRHHFSNQ
SSKFLAHL-HKEKGSVQAHEISSNSIKELSIVNEKKV-PPKNLEKGDVKDRGPPKKRRQE
LESDSESDSDMQDRKKVRMEVEQL---ETLPSGS-ALVGPLCVMDDFRDPQRWKECARQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPVSKDDRAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTQSQ
SC-LKSFLE-CHGLSLLWIWMAELGDGRGN---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQIKTAIPQFSEGDGYSSENTSRAHTPLNTPDPSTKPNTEADTDTPKKLVFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENAP---VEEDEESQPQQLQPQSLIP
QHLLPTKGDIETSLDSSKQPASEPEAEHEAEAKE-SNGPKLEESIAMETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENN----GDRGRDNVS
LRDQATTPKTPNRSREREPERQTQS-KEKKKRRSSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRLKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYESL--GYSAP
HHSFVGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPMCSPAT-----YEHTQT-LGHSVE
PS-------LATPQPVPVVQHVATPMEVS----TSQYVAQNE-AVVHQEPNV-AVLPVPA
PGPVQGQSYSVWDSNQQTVP---VQQPYSPAQSQTAIYYQGQTCQTVYG-VTPPYSQTTP
PIVQSYPQ-PGLQYIQGQQIFTAHPQGVVVQPAAAVTTIVATGQPQSLQQPELVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDEANLEHEA
EMDLGTPTYDENPMKSS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGTVYKPK--------EDTDLE

------------MKQLPSQ-------P-PPK---MGDFYD---PEH----PTPEEEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALSNEKQSDSPNSPATPLQVDSSPKAKMDTGDTFPTTEESSPPKSRVELGRIHFKKHLLH
VTSRPQLATA----TSPPPT----IQLPA-VIAES-TVDSPPSSPPPP----PPPPQATS
PSPPAST-SEPVALPHPPVTVPMTAPVPL-----PVDSAQKEPPIKIVPESLEVGMKQD-
IVSNSLEEHTIQTLREQADNPLQREDSHIGKEEEVSDGSK-TSLSSKKASSKKKSSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIEKERDFKKSSAPSKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERDRRRSRS--RSRSDRVSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRT------SSH---SYRDLRT
S-SSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSDHEAIKRCCSPPTELGFRRGS
-SYSKHDN-SASRYKSALSK-PVSKSDKFKNSFCCTELNEENK-QSH-FSLQTPCSKGSE
LRTSNKIPEREKTGAPSPSNQLNDSPTFKKLDE----SPILKR-EFTEHDSHDSIKELES
LSKVKNDQLRSFCSI--ELNINGSPET-ESDTVTFCASKTDAFSLTSDDSVTGSEVSP--
----LIKA---CMLSSNGFQNIGRCKEDDSDDTYRQHNKSQS-PFRETEPLLLPHHDKLV
SL----PVKTIDYP-----KTLIKD-PVDK-RRSCCKTKDSDRYCSPNEN-------SEA
E-NPETSVVKISSNSFMN--VHLESEIVLCDNTELTDQHSKC-ACDEYK--QSIGSTGSA
SLNHFDDVYESVGSSGIVS---SLPSGV------------RCEENTSPVLDAVQ-SKKST
EFLKYAGKETEVG--S-A-LPDSAKGFASWENRYNNVLSGQS----LQEAQEEGNSILHD
RRGRT--------EISLDEEEGRSRTHTSDDSEVVFS-YDLNLTMEDSDS-IT--YTLKC
DSSGNIP-E---I-STVHEDYSASSGSSSE-----ESGSEDTESDDSSVPRHRLQSVVVV
PKNSTLPMEETSPCSSRSSHSYRHYSDHWEDERLESRRHSYEDKFENM-TSKGCPQTEKF
F-LHKGTERNPE-TYSQFSRK-VDNH---LPEIAHSQSDGVDSTSHTDLKSDSLG-HLNS
EDT------VRAKTSRSQ--ELPVYSSDDFEDIPNKSRQQMIFSNRPDSSRLGKTE-VNF
S-SCDISHMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGACGTHKYQQSAEHFAGT
HSYWQGNGYWDPRSAGRPTGTGVAYDRIQGQVPDSLTDDRE----EESWDQRSGSHFPSQ
SSKFLFH--QKDKGSVQAPEISSNSVKDTLVPNERKE-FSKNFEKNDIKERGPPKKRRQE
VESDSESDGELQARKKMRVESEPG--ETSVLLQS-ELMGPSCAMEDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSIKLSTEVDTETPKKLVFR
RLKIISENSMDSAISDVTSELECKDGKEDLD-QLETVT---VEEDDD-----LQSQQLLP
QQPCESKVESETTIEVSKLPTSEPEADTEAELKE-SSGTKLEETIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VTERGRDAAA
FRDQT-VPKTPNRSRERDPDKPTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPFDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
S--------LAAPASVPVVPHVAASVEVS----SSQYVAQNE-SVVHQDSSV-PVMPVQA
PGPVQGQNYSVWDSNQ-QSV-SVQ-QQYSPAQSQATIYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYAQPNL-QYIQGQQIFTAHPQGVVVQPTSAVTTIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDANLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MEKRGKYSSKLERESKRTSENEVMKRCCSPPNELGFRRGS
-SYSKHEN-SASRYKSTPSK-SVPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSRGSE
VRTISKISEREKTVSPSPSNQVNDSPTFKKLEE----SPIFKS-EYIGHESHDSIKELDS
LSKVKSDQLRSYCPI--ELNINGSPGA-EPDMVTFCTSKTDTALMSSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNINRCKEKDLDDTCMQCSKSES-PFRETEPLVSPHQDKLM
SL----PVVNVDYS-----KTVVKE-PVDM-RVSCCKTKDSDVYCTSDD--NPSLCHSEA
E-DNEPSVMKISSNSFMN--VHLKSKKVICDNRNLTDQHSKF-SCEDYK--QSVGSTSSA
SVNHFDDLYQPVGSSGIASSLQSLPPGIKMDSLALL----HCGENTSPVLDVVLKKK-ST
ELLKHAEKEMIADGGSG--LPDSGRGFASWEKRHNNGLSGKC----VHEPQEEENSILPD
KRGRP--------EISLDEEGGRGHEHTSDDSEVVFSSCDLNLTMEDSDC-VT--CTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLEPRRHSYEEKFESI-ASKACPQTEKF
F-LHKGTEKNPEISFTQPSRKQIDNH---LPEIAHPQSDGVDSTSHTDVKSDPLG-YPNS
EET------MKAKIASRQQEELPVYS-DDFEDVPNKCRQQITFPSRPD-SRLGRME-LNF
PSSCEISRVDGFNSSEELRNIGWDFSQQEKPTTTYQQPDSSYGACGGHKYQQSIEQYGET
RNYWHGNGYWDPRSAGRPPGTGVVCERIQGQVPDSLTDDREE---EESWEQRGGSHFSSQ
SSMLFVNL-RKDKGSVQAPEISSNSIKDSLAMSEKKD-LLKNLEKNDMKDRGPPKKRRQE
LESDSESDGDLQDRKKVRVEVEQS--ETAVPSGS-ALVGPSCVMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGEGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVSQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADIDISKKLMFR
RLKIIXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX---XXXXXX-----XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEVYRIPKKSQXXXXXX---XTERGRDATG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKKKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAT
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPNMDPVCSPAP-----YDHSQTLVGHSTE
P--------LAAPPPVPVVPHVTAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATIYYPGQTCQTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPATAVTTIVAPGQPQPLQPPELVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------EEENEA
KIESVQKTSFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLS
VLGNEKQNDTPNSPAL-SQVDSTPKIKVDVGDTLATIEESSPPKSRVELVTL--------
------------------------------------------------------------
-----------------------------------------------VQESLEADTKQD-
IISNSSEEHIIQNLNDQADIPSQKEDSHIGKE-ELPDSSK-ISLSSKKSGSRKKYSQFEG
TFLGSESDEDSVRTSSSQRSHDLKISASTEKERDIKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRGSRASLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRGRESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKAETSYLEIERRGKYSSKLERDSKRTSENEAIKRCCSPPSDLGFRWGS
-SYSKHDY-SVSRYKPALSK-SMSKSDKFKNSFCCTELNEESK-QSHSFSLQTPCSKGSE
LRTVSKIPEREKTRSPSPSNQLNDSPTFKKLDE----SPIFKS-EFIGHDSHDSIKELDS
--KVKNDKLRNFCPI--ELNINGSPGA-ESDM-TFCTSKTDTVLMTSDDSVTGSEVSP--
----LVKV---CMSSSNGFQNISRCKEKDLEDTCMQHNKSQS-PFKEAEPLVLTRNNSIT
SL----PVTTTDYS-----KTVVKE-QVDK-RVSGCKTKDSDRYCTANE----------T
E-NTELSVKKISSNSFMN--VHLESKTVVCDKRNLTDQHSKF-TCGGYR--QSVGGTNSA
SVNHLDDLYEPIGSSDIASSLQSLPAGIK---------------NTSLGLDGALKSKKST
EVLKNARXXXXXXX-XXX-XXESGKAFASWENRPNNALSGKC----LQEAQEEGDSILHD
RRGRP--------EISLDEEERRGHAHTSDDSEVVLSSCDLNLTMEDSDG-IT--YTLKC
DSSGHAP-E---IVSTVHEDYSSSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDHWEDERLESRRYSYEEKCENI-ANKGCLHAEKF
--FHKGTEKNLEISFMQPSRKQVDNH---LPEITYSQNDGVDSTSHSXXXXXHLG-HSST
EEI------IKAKTFSRQQEELPVYS-DDFEDTPSKSRQQTTFPNRPD-SRHGKTE-LNF
S-SCDISHIDGLHSSEEHRNLGWDFSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXREE---EENWDQQGESYFVSQ
SNKFLLSF-QKDKESVQAPEISSNSVRDSVAVNERKD-FSKNLEKSDIKDRGPPKKRRQE
LESDSESDGDLQDRKKVRVDVEQG--ETSVVPGS-ELIGPSCVMDDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQXX
XXXXXXXXVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSV--KLEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQ-----
------------------------------------------------------------
----------TKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTDTDADTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QQKDRC---EFEV---------------
----------------RKRPISESGPQ---------------DPISEN------------
-----------ENKNSHHFYPTLILSVCFLQEVYRIPKKSQTEKVST---ATERGRDAVG
LRDQTTAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVXHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVMPVPT
PGPVQGQNYSVWDSNQQSVS--V-QQQYSPAQSQTTIYYQGQTCPSVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFAAHPQGVVVQPTAAVTTIVTPGQPQPLQPVRNISAAKTV
IES------------------------MTAWLFLPPSRQTQWDPPTWESPGDDASLEHEA
EMDLGTPTYDENPMKVSMAQGR------------------TLAM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

-----------------------------------------------------------A
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAIPLQVDSSPKNKMDSGETLSITEESSPPKSRVELGKIHFKKHLLH
VTSRPQLATTTSITPPSPPT----VHIPA-VIAES-IIDSPPSSPPPP----PPPPQATI
PSPPAP-IAEPVALPQTPVKVLA--APVFSPEDVAVRALK-EPPVTTVPESSEGDNKHD-
TVSNSAEEQVTEHLKEQVDTLSQKEDSHIGKEEEIPDSSK-ISPSSKKPGSKKKSSPFEG
TFLASESDEDSVRTSSSQRSHDLKSSASTEKERDVKKNSAPLKNNEDS-GKSRSKTERDD
KYFSYSKLDRDPRYVSSRCRPERERRRSRS--RSRSDRGSRTTLSYSRSERSHYYESDRR
YHRGGSPYRERTRYSRPYTDNRARESSDSDDEHKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRECKSESSYLEMERRGKYS-KLDRETKRISENEAIKRCCSPPSELGCRRGS
-SYSKHDT-SASRYKSALSK-PRSKSDKLKNSLCCAESNEESK-QSPPLGLQTPCLKTSE
VRTMTKIPEREKTRSLSPSNQLNDSPPLKKIDG----SPVFKS-EFIEHDCHDSIKELDS
LSKGKKDELRSFCPL--EFNVNGSPGA-ESDMATFCTSKTGAVLMTCDDSVSGSEVSP--
----LATV---CMLSSNGYQSISKCKEKDLDDICLQHP-SKS-PLRETESLVSPHD-KLT
S----LPVITIDYS-----RTVVKE-ALEK-RVSCCKTKDSDRYCTADE----------I
E-NVEPSVRKISSNSFMN--VHLESKTVLCDNRSLTDQHSKF-ACEEYQ--QSVGSTSSA
YVNHFDDLYEPIESSDIASS-----PGI---------------KDTSPVPDAVLTDKNST
EFLKHAETT--IEVDSG--LPDSRKGFASWENRRNNGLLGHG----LQEAQEEGNSILPD
RRGRP--------AISLDEEGERGHAHTSDDSEVVFSSCDLNLTMEDTDG-AP--YTLKC
DSSGHAT-E---IVSTVHEDYSGSSESSSD-----DSESEDTESDDSSIPRNRLQSVVVV
PKNSTLPMDETSPCSSRSSQSYRHYSDHWDDERLESRRHSYEEKFENM-TSKGCPQTEKF
F-LHKGAEKNPEISFTQFSRKQVDKH---LPEIAHPQSDGVDSTSHADVKSDSLLSHLNA
EDI------VK-GKTSRQQEELPVYSSDDFEEIPSKSRQQIPFPNRPD-SRLGKME-LTF
SSSCDISRMDSLHSSEELRNLGWDLTQQERPTTTYQQPDSSYGAYGAHKYQQTAEQYGGP
RHYWHSNGYWDPRSAGRPPGSAVTYDRMQGQVPDSLTDDREE---EENWDQRGGSHFSGQ
SNKFLLSL-QKDKGSVQAPEISSNSIKDSLAVNERKE-FSKNFEKTDLKERGPPKKRRQE
LESESESDGELQDRKKVRVEIEQE--ETSVPPHS-ELIGPSCVMGDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKEERAQGEIACGEDCLNRLLMI
ECSSRCPNGDFCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQVNTNT
DV-NY---Q-R-PEMALWLKVVEHYSGAV-------------------------------
--------------------------------------PDPEF------------KQIFL
TLSCIAYGLF--------------------------------------------STLLLG
ST------------------------------------------IM--------------
----------------FSTSTINLSFGSLLQEVYRIPKKSQTEKEST---VTERGRDIVA
FRDQTAAPKTPNRSRERDSDKQTQN-KEKRKRRGSLSPPASAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYAAPTD-GVVHQDSNV-AVMPVPA
PGQVQGQNYSVWDSNQQSVS--VQ-QQYSPAQPQAAIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQSSL-QYIQGQQIFTAHPQGVVVQPTTAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PSWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDLTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
LSSPAP-VTEPVALPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
IFLGSESDEDSVRTSSSQRSHDLKISASIEKERDFKKSSAPLKSEDLG-KSSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEIERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----LPIFKS-EFITHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLITSDDSVTGSELSP--
----LVKA---CMLSSNGFQNISRCKEKDLDDTCMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTVDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTLNDS-NPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSKKSS
EFLKHAGKETIVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPE
RRGRP--------EISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSND-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESI-ASKACPQTDKF
F-LHKGTEKNPEISFTQSSRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDPLG-HPNS
EET------VKAKIPSRQQEELPIYS-SDFEDVPNKSWQQTTFQNRPD-SRLGKTE-LSF
SSSCEIPHVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGACGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKFLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETLVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVDSETNIEASKLPTSEPEADAEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TTERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKAS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------EEENEA
KIENVQKPGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPATPLQVDSTPKSKMDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPPLTTTTAAASPSPPI----VHLPA-IIAESTTVDSPPSSPPPP----PPPPQATT
PSPPAP-MIEPTALPHTSVTVPVTA-PVSLPVDVAVRAPK-EPPVTIVPESLEVDTKQD-
TVSNSLEEHIIQNLNEQADIPSQKEDSHIGKEEEIPDSSK-ISLSVKKPSSKKKSSQFEG
TFLGSESDEDSVRTSSSQRSHDLKISASIEKERDLKKSSAPSKSEELG-KSSRSKTERDD
KYFSYSKLERDTRYMSSRCRSERERRRSRS--RSRSERGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYIDNRARESSDSEDEYKKSYSRRT------SSHS-SSYRDLRT
S-SSYSKSDRDCKTETSYVEIERRGKYSSKLERESKRTSESEAIKRCCSP-SELGFRRGS
-SYSKHDY-SASRYKSALSK-PISKSDKFKNSFCCTELNEESK-QSHTFSLHTPCSKGNE
LRTINKISEREKTGCPSPSNRLNDSPAFKKLDE----SPIFKS-EFIGHDSHDSIKELDS
LSKMKNDQIRSFCPI--ELNINGSPGA-ESDSATFCTSKTDVILMTSDDSVTGSEVSP--
----LVKP---CLFSSNGFQNISKCKEKDLDDTCMQHSKSKS-PFKETEPLVSPHHDKLM
SL----PVMTTDYS-----KT-VKE-PVDM-RVSCCKTKDSDRYSTTNEN-------SEA
E-NIDPSVMKISSNSFKN--VHLESKTVICDNRNLSD-HSKF-ACEEYK--QSVGSTSSA
SVNHFDDLCEPIGSSGIASSLQSLPLGI------------KCGENTSPILDAVLKSKKNT
EFLKHAGKETIEDVGSG--LPDSGKGFASWENRHNNGLSGKC----LQEAQEEGNSILLE
RRERP--------EISLDEEGDRGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YSLKC
DSSGHAP-E---IVSTVHEDYSGSSEGSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDHWEDERMESRRHSYEEKFESI-ASKGCPQTDKF
F-LHKGIEKNLEISFTQSSRKQVDNH---LPEITHPQSDGVDSTSHTDVKSDPLG-RPNL
EEA------VKAKTSSRQQDDLPVYSSDDFEDVPSKSRQQTTFPNRPD-SRLGKTE-LSF
SSSCEISRMDGLHSSEELRNLGWDFSQQEKPTTTYQQPDSSYGACGAHRYQQSVEQCS--
-GYWQGNGYWDPRSAGRPPGTGVAYDRIQGQVPDSLTDDREE---EDSWDQRGGSHFLSQ
SNKYLLSF-HKDKGSVQAPEISSNSIKDSLSVNERKD-FSKNLEKNDIKDRGPPKKRRQE
LESDSESDSELQDRKKVRVEMDQG--ETSVPLGS-ALIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVTSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVT---VEDEEE-----LQSQQLLP
QQLLESKVESETTVETSKLCTSEPEADTEIELKE-SNGSKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKDSS---VTERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMEPVCSPAP-----YDHAQPLVGHSTE
P--------LAAPPPVPVVPHAAAPVEVS----SSQYVAQSD-GVVHQDSTV-AVMPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQTSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVTPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

---------------------------------------------------PLGLQAHAA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMDIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-ITEPVALPHTPVTVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIERERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDSIKELDS
LSKVRNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSNNPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSRKSS
EFLKHAGKETVVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGRVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPVEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ANKACPQTDKF
F-LHKGTEKNPEISFTQSNRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPVYS-SDFEDVPNKSWQQSTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPEKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAASVEVS----SSQYVAQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------EEENEA
KIESVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAL-SQVDSTPKIKVDIGDTLTTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTSAVASPSPPT----VQIPAAVIAESTTVDSPPSSPPP----PPPPPQATT
PSSPAP-ITEPGASPHTPVTVLTTA-PVSLPVDVAVKTLK-ESPATLVQESLEVDTKQD-
VISNSSEEHVTQNLNDQVDTPSQKEDSHIGKEEEIPDSSK-ISLSSKKSGSKKKYSQFEG
TFLGSESDEDSVRTSSSQRSHDLKISASIEKERDIKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKFERDTRYVSSRCRSERERRRSRS--RSRSDRGSRASLSYSRSERSHYYDSDRR
YHRN-SPYRERTRYSRPYSDNRGRESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEIERRGKYSSKLERESKRTSENEVIKRCCSP-SDLGFRWGS
-SYSKHDY-SASRYKSALSK-SMPKSDKFKNSFCCTELNEESK-QSHSFSLQAPCSKGSE
LRTISKIPEREKTGSPSPSNRLNDSPTFKKLDE----SPIFKS-EFIGRDSHDSIKELDS
LSKVKNDKLRNFCPI--ELNINGSSGA-ESDV-IFCTSKTDAVLMTSDDSVTGSEVSP--
----LIKA---CISSSNGFQNI-RCKEKDLEDTCMQH-KSQS-PFKETEPLVLPRKDNNT
SL----PVMTTDCS-----KTVVKE-PVDT-RVSCCKTKDSDRYCTANES-NPSLCYSEA
E-NIEPSVMKISSNSFMN--VHLESKTVTCDKRNLTDQHSKF-TCGEHR--QSVGSTSSA
SVNHLDGSYEPIGSSGIASSLQSLPPGIK------------CGENIFPVLDGVLKSKKST
DVLKHAGKEKILDVSSG--FPDSGKAFASWENRHNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EITLDEEGRRGHAHISDDSEVVLSSCDLNLTMEDSVG-VT--YTLKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSNQSYKHYSDHWEDERLESRRHSYEEKFENI-ASKGCLQTEKF
F-FHKGTEKNPEISFMQSSRKQVDNH---LPETAHSQNDGVDSTSHTDVKSDLLG-HSNS
EEI------VKTKTSSRQQEELPAYSSDDFEDIPSKSRQQTTFPNRPD-SRLGKTE-LNF
S-SCDISRVDGLYSSEELRSLGWDFSQQEKPTTTYQQPDSSYGACGAHKYQQSAEQYGGN
RNYWQGNGYWDPRSAGRPPGSGVAYERIQGQVPDSLTDDHEE---EENWDQRGESHFISQ
SNKFLLSL-QKDKGSVQAPEISSNSVRDSIAISERKD-FSKNLEKSDIKDRGPLKKRRQE
LESDSESDGELQDRKKVRVDIEQG--ETLVAPGS-ELIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRET---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVT---VEEEEE-----MQSQQPFP
EQLPESKVEGENTVEASKLPALEPEADTEIEPKE-SSSTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VTERGRDAVG
LRDQTAAPKTPNRSRERDTDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHTQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVMPVPT
PGPVQGQNYSVWDSNQPSV--NVQ-QQYSPAQSQATIYYQGQTCSSVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVTPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------LS-LCGPQ------K-TPK---ASIFLE---IAHQTSEDDNREEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLT
ALGNDKQSDTPTSPAVPLQVDLTPKIKMDVGETLSTAEDSSPPKSRVELGKIHFKKHLLH
VTSRPLLAATTPVTSPP-PT----VPLPA-VIAESTTVDSPPSSPPPPP---PPPPQATV
PSPPAP-ITEPVALPHAPIMVLMTA-----PVDLAVRALK-EPPVTIEPESSEVDTKQD-
TVSHSSEEHIAPTLSEQAHLPSQKEDSHIGKEEESPDSSK-RSLSSRKTGSKKKPSQSES
TFLGSESDEDSVRTSSSQRSHDLKFPASIEKERDSKKSLAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYMSSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YR---SPYRERARYSRPHTDNRARESSDSEDEYKKTHSRRT------SSH--SSYRDPRA
A-SSYSKSDRDCKTES-HSEMEKRGKHSSKPERESRRTSENEATKRCCSPLNELGFRRGS
-SYSKHEN-SASRYKSAPSK-SISKSDKSKNSFCCAELTEEIK-HTHSFSLQTHCSKGSE
VRVISKLPEREKTGSPPLSNRLNDSPAFKKLEE----SPIFKS-EFIGHDSHDSIKELDS
LPKVKNDQLRSYCPM--ELNINGSPDA-ESDLVTFCTSKTDTVLMSSDDSVTGSEVSS--
----LVKA---CVLSSNGFQNIDSCKEKDLDDTCMQCSKAES-PFRETEPPVSPHQDKLM
SS----PVMTVDYC-----KTVVKE-PVDM-RVSSCKTKDSDVYCASNDN-NPSSCHSAA
E-DTEPPVRKISSNSFMN--VHLKSKTVICDNRSLTDQHSKF-ACKEYK---SVGSASSA
SVNHFDDLYQPIESSGIASSLQSLPPGITVDSLALL----QCGENTSPVLGAVLKSK-ST
EFAKHGEKE-MLEVGSG--LPALGRGVASWENRHNNGLSGKC----LHEAQEEGNSMLPD
KRGRP--------EISLDEEGRRGHEHTSDDSEVVFSSCELNLTTEDSEY-MT--YTLKC
DSSGHAS-E---VVSTVHEEYSGSSESSSD-----ESDSEETDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSHSYRHYSDHWEDERLEPRRHSYEEKFESI-ASKACPQTEKF
F-LHKGTEKSSEMCFTQMSRKQIDNH---LTEIAHPQSDGVDSTSHSDVKSDPGG-HPGF
EET------LRAKIAARQ-EELPLYS-DDFEDVQSKCWQQTPFPDRPD-SRLGRTE-LNF
SSSYEISRVDGFHSSEELRNMGWDFSPQEKPTTTYQQPDSSYGGRAGHKYQQGTEPYAGT
RSSWQGNGYWDPRSAGRPPGTGVVYDRVQGQVPDSLTDDREE---EENWDPRVGSQFSSQ
SGKFFVSL-QQDKGSVQAPEISSNSIKDSLVINDKKA-LSKNLEKNDMKDRGPPKKRRQE
LESDSESDGELQDRKKVRVEAQLC--ETAAPPGS-ALAGPSCVMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECAPLSKEERAQGEVACGEDCLNRLLMI
ECSSRCPNGDHCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SR-LKSFLE-RHGLSLLWIWMAELGDGRES---NRKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLETIP---VEEEEE-----LQSQQLLT
QQLPESKADSEIAGEASKLPTPEPEADVEVETKE-NSSAKLEEPVAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VTERGRDAAV
FRDQTAAPKTPNRSRERDTDKQTQS-KEKRKRRGSLSPPSSAYERGTKRPEDRYDTPTS-
-KKKVR-KDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGIASPLPYDSL--GYSAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSLDPVCSPAP-----YDHSQPLVGHSAE
P--------LAAPPPVPVVPHVTAPVEVS----SSQYVAQSE-GVVHQDSSV-TVLPVPA
AGPVQGQNYGVWDSSQQPVS-VQQ-SYSTPAQSQPSIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYLPGQQLFSA--PGVVVQPAAAVTTVVAPGQPPPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDPPTWDSPGDEASLEHEA
EMDLGTPTYDENPMKKSREEPVTA------------------------------------
------------------------------------------------------------
-----------------------

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASLPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
LSSPAP-VTEPVALPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESSEADTKQD-
TVSNSSEEHVTQILNEQADISSKKEDSHIGKVEEIPDSSK-ISLSCKKTGSKKKSSQSEG
IFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFGLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----LPIFKS-EFITHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSELSP--
----LVKA---CMLSSNGFQNISRCKEKDLDDTCMLHKKSES-PFRETEPLVSPHQDKLI
SL----PVMTMDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDS-NPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKTVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSGIVSSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSKKSS
EFLKHAGKETIVEVGSD--LPDSGKGFASRENRHNNGLSGKC----LQEAQEEGNSILPE
RRGRP--------EISLDERGE-GHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSND-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ASKACPQTDKF
F-LHKGIEKNPEISFTQSSRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDPLG-HPNS
EET------VKAKIPSRQQEELPIYS-SDFEDVPNKSWQQTTFQNRPD-SRLGKAD-LSF
SSSCEISHVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGACGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGIVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKFLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPVIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNIPDPSTKLSTEADADTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVDSETNVEASKLPTSEPEADAEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TTERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKAS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLPS-Q------P-PLK---MGDFYD---P--EH------------
-----PTPDFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPATPLPVDSNPKIKMDIGDTLPNTEESSPSKSRVELGRIHFKKHLLH
VTSRPLLTTTTAVVSPPPPT----VQLPA-VIAEST-VDSPPSSPPPP----PPPPQATI
PSPPAP-ISEPVALPHTSVTSL------------------------------EVDIKQD-
TVSNSLEEHTTQNLKDGAENPLQKEHSHIGREEEISDSSK-INLSSKKAGSKKKSSQFEG
TFLA-----------------------SIEKERDFKKSSAPLKSEDFG-KSSRSKTERDD
KYFSYSKLERDARYVSSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEDEYKKTYSRRT------SSSH-SSYRDLRT
S-SSYSKFDRDCKTENLYVEMERRGRYSSKLERESKRTSEHEGIKRCCSPPSELGFRRGS
SSYSKHDN-SASRYKSALSK-PISKSDKFKNSFCCAELNEESK-QSH-FSLQTPCSKGSE
LRIISKIPEREKTGSPSPSNQLNDLPTFKKLDE----SPILKS-EFIGHDSHDSIKELDS
LSKVKNDEIRNLCPI--EFNINGSPGT-ESDVVTFCTSKTDAILMTSDDSVTGSEVSP--
----LVKA---CLLSSNGFQNISRCKE-DSDDACTQHSKSKS-PFRETESLVSPRHDKLM
SL----PIKTVDYS-----KTVIKE-PVDK-KVSCCKTKDSDRFCAANE----------I
E-NTEPSVTKISSNSFMNVNVHLESKTVKCDNRNMTDQQSKF-VCDEYK--QSIGSTSSA
SGNHLDDLYEPIGSSGIIVSHQSLPPRI------------KCDEDTSPVLDAVLKSKKST
ENLKYAGKET-VEVGSA--FPDSGKEFASWENRHNNGLSGQC----LQEAQEEGDSILPD
RR-----------EISLDEEEQRGHTHTSDDSEVVFSSCDLSLTMEESDG-VT--YTLKC
DSSGHAP-E---IVSSIHEDYSGSSGSSSD-----ESDSEDTESDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHFSDHWEDERLESRRHSYEEKFESM-TSKGCSQTEKF
F-LHKGIEKNPETSFTQFNRK--DNL---LSEIAHPQSDGVDSTSHTDVKSNLLV-HLNS
EET------IRAKTSSRQ--ELPVYS-DDFEDVPSKSRQQIFFSNRADSSRLGKTE-LNF
SSSCDISRMDGLHSSEELRNLGWNFSQQEGPTTTYQQPDSSYGTCGAHKYQQSAEHYGGT
HNYWQGNGYWDPRSAGRPPGTVVVCDRIQGQVPDSLTDDRE----EENWDQRSGSHFPSQ
SNKFF-SL-QKDKGSVQAPEISSNSIKDSFAMNERKD-FSKNMEKNDIKDRGPPKKRRQE
LESDSESDGELQDRKKVRVEIEQG--EIPVPLSS-ELIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEVDTDTPKKLMFR
RLKIISENSMDSAISDVTSELECKDGKEDLD-QLENVT---VEEEEE-----LQSQQLLP
QQLSESKVESEPTLEASKLPTSEPEADTEIEHKD-SCGTKLEETIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKVQTEKENT---VTERGRDAIV
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQSLGMTSPLPYDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAS-----YDHTQPLVGHSTE
P--------LAAPSSVPVVPHVAASVEVS----SSQYVAQNE-SVVHQDSNV-AVMPVQA
SGPVQGQNYSVWDSNQQSI--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPD------
----------------------RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-ITEPVALPHTPVTVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIERERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDSIKELDS
LSKVRNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSNNPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSRKSS
EFLKHAGKETVVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGRVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPVEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ANKACPQTDKF
F-LHKGTEKNPEISFTQSNRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDVPNKSWQQSTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDRE----EENWDQQDGSHFSDQ
SNKYLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPEKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAASVEVS----SSQYVAQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPVRNIS-----
-TILPPKPPKM--ILFPS---------PDSMAIFSLSRQTQWDPPTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLPSQ-------P-PPK---MGDFYD---PEH----PTPD------
----------------------RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDSPNSPATPLQVDSSPKVKMDTGDTFPTTEESSPPKSRVELGRIHFKKHLLH
VTSRPQLATT----TSPPPT----VQLPA-VTAES----TPPSSPPPP----PPPPQATS
PSPPAPISAEPVASPHLPVTVLMTA---------PVDSAQKEPPAKTVPESLEVGMKQD-
IVSNSLEEHTIQTLKEQADNPLQREDSHIGKEEEVSDGSK-TSLSSKKASSKKKPSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIEKERDFKKSSAPSKSEDLG-KSLRSKTERDD
KYFSYSKLERDTRYVSSRCRSERDRRRSRS--RSRSDRVSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRLYTDNRARESSDSEDEYKKTYPRRT------SSH---SYRDLRT
S-SSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSEHEAIKRCCSPMTELGFRRGS
-SYSKHDN-SASRYKSALSK-PVSKSDKFKNSFCCTELNEENK-QTH-FSLQTPCSKGSE
LRTSNKIPEREKTGSPSPSNQLNDSPTFKKLDE----SPILKP-EFIEHDSHDSIKELES
LSKVKNDQLRSFCSL--ELNINGSPET-ESDMATFCASKTDAFLLTSDDSVTGSEVSP--
----LIKA---CMLSSNGFQNIGRCKEEDSDDIYRQHSKSQS-PFRETEPLLSPHHDKLL
SL----PVKTIDYS-----KTLIKD-PVDK-RRSCCKTKDSDRYCSPNEN-------SEA
E-NTETSVVKISSNSFMN--VHLESKIVLCDNTELTDQHSKF-ACGEYK--QSIDGPSSV
SLNHFDDPYESAGSSGIVSSLQSLPSGV------------KCEENTSPLLDAVQ-SKKST
EFLKYAGKETEVG--S-A-LPDSGKGFASWENRHNNVLSGQS----LQEAQEEGNSILHD
RR--P--------EISVDEEEGRGRTHTSDDSEVVFS-YDLNLTMEDSDS-IT--YTLKC
DSSGNAP-E---M-STVHEDYSESSGSSSD-----ESDSEDTESDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSHSYRLYSDHWEDERLESRRHSYEDKFESM-TSKGCPQTEKF
F-LHKGTERNSETSYSQFSRK-VDNH---LPEIAHSQSDGVDSTSHTDLKSDSLG-HLNS
EDT------VRAKTSRSQ--ELPIYSSDDFEDIPNKSRQQVIFSNRPDSSRLGKTE-LNF
S-SCDISCVDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGACGTHKYQQNTEHFTGT
HSYWQGNGYWDPRSAGRPPGT---YDRIQGQVPDSLTDDREE---EESWDQRSGSHFSSQ
SSKLFFH--QKDKGSVQAPEISSNSVKDSLVPNERKE-FSKNFEKNEIKERGPPKKRRQE
VESDSESDGELQARKKVRVESEPR--ETSVPLQS-ELMGPSCAMDDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECAPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNVHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVSMLS------------------------------EVLDVCVCIKNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSIKLSTEVDTETPKKLIFR
RLKIISENSMDSAISDVTSELECKDGKEDLD-PLETVT---VEEDDD-----LQSQQLLP
QQLCESKVESETTIEVSKLPTSEPEADTETELKE-SSGTKLEETIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VTERGRDAAA
FRDQT-VPKTPNRSRERDPDKPTLN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPFDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
S--------LATPSSVPVVPHVAASVEVS----SSQYVAQNE-SVVHQDSSV-PVMPVQA
PGPVQGQNYSVWDSNQ-QSV-SVQ-QQYSPAQSQATIYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPPTAVTAIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRISTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

-------------------------------------------M--FSWLDGNREEENEA
KIESVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAL-SQVDSIPKIKVDIGDTLVTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTSAVASPSP-T----VQLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
PSSPAP-ITEPVASPHIPVTVLTAA-PLSLPVDVAVRSLK-EPSVTLVKESLEVDTKQD-
IISNSSEEHITHNLNDQVETPSQKEDSHIGKDEEIPDSSK-ISLSSKKPVSKKKYSQFEG
TFLGSESDEDSVRTSSSQRSHDLKISASIEKEREIKKSSAPLKSEDLG-KSSRSKTERED
KYFSHSKLERDTRYISSRCRSERERRRSRS--RSRSDRGSRAGLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRGRESSDSEDEYKKTYSRRT------SSHS--SYRDLRT
--SSYSKFDRDCKTETSYLEIERRGKYSSKLERDSKRTSENEAIKRC-SPPSDLGFRWGP
-SYSKHEY-STSRYKSALSK-SVPKSEKFKNSFCCTELNEESK-QSHSFSLQTPYSKGSE
LRTVIKIPEREKTGSPSPSNRLNDSPTFKKLDE----SPTFKS-EFVGRD---SIKELDS
LSKARNDKLRNFCPI--ELNINGSPGA-ESDVTTFCTSKTDAVLMTSDDSVTGSEVSP--
----SVKA---CMSSSNGFQNI-RCREKDLEDTPMQHSKSQS-PFKETEPLVSLCNDSIV
SL----PVMTTDYS-----KTV-KE-LVDV-RVSCCKTKDSDRYCTADDS-NP-LCYSEA
E-NTEPSVAKISSNSFMN--VHLESKTVVCDKRNLTDQHSKF-TCEENK--QSVGSTSSA
SVNHLDDLYESIGSSSIGSSLQSLPPGIKMDSLTLL----PCGKNTSPVLDGLLKSKKCT
EVFKHAGKEKMVDVGSG--FSHSVKAFACWENRHNNGLSGKC----LQELPEEGNSILPD
RRGRP--------DNSLDE--GRGHAHTSDDSEVVLSSCDLNLTMEDNDG-IT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDHWEDERVESRRHSYEEKFESI-ASKGCPQTEKF
F-FHKGTEKNLEISFIQSSRKQLDNH---LPEIAHSQSDGVDSTSHTDVKSDLLG-RSNS
EEI------IKAKTSFRQQEELPVYSSDDFEDIPSKSRQQTSFLNRPD-SRLGKTD-LNF
--SCAISCMDGLHSSEDLRTLGWNFSQHEKPTTTYPQPDSSYGACGAHKYQQSAEQYGGS
RNYWQGNGYWDPRSAGRPPGSGVAYDRIQGQVPDSLTDDREE---EENWDQRGESHFLSQ
SNTFLLSL-QKDKGSVQAPEISSNSIRDSLAVNERKD-FSKNLEKSDIKDRGPPKKRRQE
LESDSESDGELQDRKKVRVDIEQG--ETSVPPGS-DLIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPVIQRWSQTKTAAPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADADTPKKLVFR
RLKIISENSMDSAISDAASELEGKDGKEDFD-QLENVT---VEEEEE-----MQSRQPFS
EQLPESKVESETTVEASKLSTLEPEADTEMEPKE-SSGTKLEEPTAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLANKLLDSWKDLKEVYRIPKKSQTEKENT---VTERGRDAVG
LRDQTAAPKTPNRSRERETDKQTQS-KEKRKRRGSLSPP-SAYERGTKRSDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LAAPPPVSVVPHVAAPVEVS----SSQYVGQSD-GVVHQDSSV-AVMPVPT
PGPVQGQNYSVWDSNQQSV--NVQ-QQYSPAQSQATIYYQGQTCPSVYG-VTSPYSQTAP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVTPGQPQPLQTPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPIFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----VPLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
SSSPAP-VTEPVALPHTPVTVLMAA-PVPLPVDVAVRALK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITHNLNEQADISSKKEDSHIGKDEEIPDSSK-ISLCCKKTGSKKKYSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSANIEKERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEDYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAMKRCCSSPNELGFRRGL
-SYSKHDS-SASRYKSTLSK-PISKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGNE
LRMINKNPEREKPGTPSPSNQLNDSPAFKKLDE----LPIFKS-EFIAHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGT-ESDLATFCTSKADAVLMTSDDSVTGSEVSP--
----LVKA---CVLSSNGFQNISRCKENDLDDTCMLHNKSES-PFRETEPLVSPHQNKLM
SL----PVMTIDYS-----KTVVKE-PVDM-RVSCCKTKDSDIYCTSNDS-NPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKTVISDHRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSGIASSFHSLPPGIKVDSLTLL----KCGENISPGLDVVLKSKKSS
EFLKRAGKETIVEVGSD--LPDSGKGFASREKRHNNGLSGKC----LQEAQEEGNSILPV
RRGRP--------EISLDEGGERGRMHTSDDSEVVF-SCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PRNSTLPMEETSPCSSRSSHSYRHYSDHWEDERLESRRHSYEEKFESI-ASKACLQTDKF
F-LHKGTEKNSEISFTQSSRRQVDNH---LPELSHPQSDGVDSTSHTDVKSDHLG-HPNS
EET------VKAKIPCRQ-QELPIYS-SDFEDVPSKSWQQTAFPNRPD-SRLGKTE-LSF
SSSCEIPHVDSLHSSEELRNLGWDFSQ-EKPTTTYQQPDSSYGACGGHKYQQSAEQYGGT
RDYWQGNGYWDPRS-GR-PGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKFLVSL-QKDKGSVQAPEISSNSIKDIVAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQE--ETSLPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-PLENVP---VEEEEE-----LQSQQLLP
QQLPECKVDSETSVEASKLPTSEPEADAEIEPKE-SNSTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVA
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPASAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVTQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQPV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMIVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
VLGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-VTEPVVLPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDSIKELDS
LSKVKNDQLRSFCPT--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSSNLSLCNSEA
E-NIEPSVIKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSRKSL
EFLKHAGKET--EVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ASKACPQTDKF
F-LRKVTEKNPEISFTQSSRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDVPNKSWQQTTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSI-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTDADTDTPKKLMFR
RLKIVSENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKLESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVTQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------TEKRGKYSSKLERESKRTSEIEVMKRCCTPPSDLGFRRGS
-SYSKHDS-NASHYKSTPSK-STPKSDKFKNVFCCTEFNEEIK-QSHSFGLQTPCSKGSE
FRMMNKIPEREKTGSLSPSNQLNDSPTFKKLDE----SFIIKS-EFIGHDSHESIKELDS
LSKGKHDQLRTYCPI--ELNVNGFPGA-ESDLTTFCTSKTESVLMSSDDSVAGSEVSP--
----LIKA---CMRSSNGFQNTSRCKEKDLDATYMHHSKSES-PFRETEPPVSPHPDNLV
TL----PDMAIDYS-----KAV------KE-PVSCCRTKDSDIYCTSNDS-NPSLCHSEA
E-NIETSVVKMSSNSFMNIRLD---STAISDSRNMTDQTAKF-ACEEYK--QSVGSTSSV
SVNHIADLCQPIRSSEIASSLQSLSPEIKVDTLTLL----QYGENTSPVLDAVLITEKST
EFLKHAGEETR-EVN-RD-LPDSRRGFSSWENRHNNGLSGKC----LQEE---ESSTLPG
RR--P--------EIS--SDGERGHVHTSDDSEAVFL-CNLNLAMXXXXXXXX--XXXXX
XXXXXXX-X---XXXXXXXXXXXXXXXXXX-----XXXXXXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXDKF
F-AYKGAEKNPEKSFTHPHRKQMDNH---LPEMAHSQSDGVDSTSHPDVKSDHLG-HPGS
AET------IKFKIASRQQEELSIYS-DDFEDVPNKSHQQTTFPTRPD-SRLGKTD-LSF
SSPCEISRVESFHSSEELRNVGWDFTQSEKPTTTYQQPDSSYGACGGHKYL-SAEQYGGT
RSHWQGNGYWDPRSAGR-PGTGVVYDRIQGQVPDSLTDDREE---EENWDQRGGSHFSNQ
SSKFLLSIQQKDRGSVQAPEISSNSIKDSLAVNEKKD-LTKSLERNDMKDRGPLKKRRQE
LESDSESEAELQDRKKVRVEAEPG--ETAAPPGS-ALFGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECAPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLKAARDL PSXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX WTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDAASELEGKDGKEDLD-QLEHVP---VEEEDE-----LQAQQPIT
QQLSEPKGDGEAAVEVSKLPVSEPEADTEIEPKE-SNGTKPEEPIVEETPSQDEEEGVSD
VESERSQEQTDKTVDISDLATKLLDSWKDLKXXXXXXXXXXXXXXXX---XTERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAT
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAS-----YDHTQ-LVXXSAE
P--------IAAPPPVPVVPHVSAPVEVS----SSQYVAQND-GVVHQDSSV-TVLPVPT
PGTVQGQNYGVWDSNQQSQSISNVQQQYSPAQSQATIYYQGQACPTVYG-VTSPYSQTTP
PIVQSYAQSSL-QYIQGQQIFTAHPQGVVVQPTASVTTIVAPGQPQPLQPPEMVVTXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXTSKKPKTAEADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECDENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

---------------------------------------------------PLGLQAHAA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPSAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASLPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-ITEPVALPHTPVTVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIERERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDSIKELDS
LSKLRSDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRILHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSNNPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGVKVDSLTLL----KCGENTSPVLDAVLKNRKSS
EFLKHAGKETVVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGRVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPVEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ANKACPQTDKF
F-LHKGTEKNPEISFTQSNRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDIPNKSWQQSTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPEKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAASVEVS----SSQYVAQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

---------------------------------------------------PLGLQAHAA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-ITEPVALPHTPVTVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIERERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDRIKELDS
LSKVRNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSNNPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSRKSS
EFLKHAGKETVVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGRVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTAHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPVEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ANKACPQTDKF
F-LHKGTEKNPEISFTQSNRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDVPNKSWQQSTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPEKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAASVEVS----SSQYVAQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------TEKRGKYSSKLERESKRTSENEAVKRCCSPSNELGFRRGS
-SYSKYDN-SASRYKSASSK-PVPKSDKFKNSFCCTELNEETK-QSHSFSLQTPCSKGSE
LRMISKIPEREKTGSPSPSNRLNDSPTK-KLDE----SPVFKS-EFIRHDSHDSIKEFDS
-SKVRNDQLRSYCPI--ELNINGSPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
----XXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XX----XXXXXXXX-----XXXXXX-XXXX-XXXXXXXXXXXXXXXXXXX-X--XXXXXX
X-XXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX-XXXXXX--XXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX----XX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXX
XXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX--XXXXX
-----XX-X---XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXSCIPRNRLQSVVVV
SKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFEST-SSKACTQTEKF
F-LHKGMEKNPEITFTQSSRKQIDNH---LPEIVHPQSDGVDSTSHTDVKSDSLN-HPNV
EET-------NSKIASRQQEEMPVYSSDDFQDVTNKSRQQTTFPNRPD-SRLGKTE-MSF
SSSCEISQVDSFHASEEHRNLGWEFSQQEKPTTTYQQPDSSFGVCGGHKYQQSAEQYGGT
RNYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EENWNQRSGSHFSSQ
SSKFFLSL-QKDKGSVQAPEISSNSIKDSVTVNEKKD-LSKNLEKSDMKDRGPPKKRRQE
LESDSESDSELQDRKKVRVEVEQG--DTTVSPGS-ALVGPSCVMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKEERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG XEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKDRSRKKDSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX---XXXXXX-----X-XXXXXX
XXXXXXXXXXXXXXXXXXXXXX---XXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIERGRDAVG
FRDQTAAPKTPNRSRERDSDKQTQN-KEKRKRRGSLSPPSSAYERGSKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNMGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
A--------LAAPPPVPVVSHVAAPVEVS----SSQYVTQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYGVWDSNQQSVS---VQQQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQTLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGVVYKPK--------EDTELE

----------------------------------------------------------QG
KPENVQKAGFVKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGSEKQNETHNSPAVPLPTDFSPKIKMDLGDTSSSAEESSPPKPKVELGKIHFKKHLLS
VTAKPLPAAVVLSPSL---E----ALAPA----EVTTAELP-L--------TPSPPHSQT
AFPPAP-LLTAVTLPQPPVAVSVTLASLLLPPVESEVQTSKEPTNAVVKETLELDIKHD-
PASNSSEEHAAQIMSEQMEITSQQEESHIGKDEEISDSSKGASLCSKKQGSRRKFSQADA
TLLGSESDEDSIRTSSSQRSHELKIS-STEKERDPKKSSTSLKSEDSVKSSSRSKLDRDE
KHSSYSKAERDSRYMSSRSRSDRERRRSRSHSRSRSDRGSRTSSSYSRSERSYYYESDRR
YHRS-SPYRERTRYSRSHTDNRTRESSDSEDEYRRTHSRSSDS--RRTSSH-SSYRDSRT
--SSYSKSERDSKTESSYAETERRGKSS-KSDRESKRTSESDVSKRC-SPLNELGYRRVT
SHSKPDSNVNSSRYKYTPTKTSAPKSDKSKGSFCCTESVEEIKQQSNSLGLETSCLKSSE
LRMTI-IKKFESEHTVSPFSQLNDSPSFKKLDESKESSPDLKS-ELIGNDCHDSIKEPES
LIKVKRDQLRTYCPL--ELNINGSPEGRSDDLATFCASKIEDVAVSSDDSLSRSEVSP--
----KIKSNTFYVLPSNGFQSIYKSKEQDLDDSHMQSEF-ND-LFKETETPVPSEQYDDI
S-----SVTNIDHS-----EMLVKK-LDDL-TTACNRTKDSDFCYVSDT--SPSLYHSEV
EIEVEPTYTKVTQETLMD--IHVEPQTVICNYENAEDQNSAKSACEDELYDRSPSHEMSL
I----------VDNSSRDSSQEECSLEIKLDNEIITR---QPEENLASELDRAMQNK-NE
ECLQLSETEVIIELDAQHIGPDVEKGKQSFKKEHSYYLEVPEEHLAKEETAEERSEVLVE
-RTRPDDFKDQSLEVLIGKDEENESLMVSGFSDALFPSCDVIVIAEETET-VT--QAATC
DSSGNTS-E---FISVHDDDYSDTAESESDQDS-EESDTEDSDS-DDSVPRNRLQSVVVV
PKNSTLSMEESSPCSSRSSQGNARYSDHWDDDRPESSKPYYEERSENA-SNKNGPHIENK
CSPSRGMDKSPA-TSTELSRKETEDL---QPDISQPQSDGVDSTSQTDLTSNSNGQPNPD
ERIILKELMPVARPLSRQQDEQPFCFSESYESTENKSRHQTN-SSKPD-SRQGKAGFSNL
SGTGDFSRLDGFHSTEDLGSLGWDFSQPEKPSSTYQQPDSSYGMYSGYVCQQGPGSYCGS
QNYWQGNGYWDSRPCSRS--SGINYERIQGQVPDSLTEDHEEYEQDDNWDDDCKAHFPIQ
SSKFHT-LGDQEKGSVQAHEISSNSAKEPTVVNEKKE-QAKILEKHDVKERGPPKKRRQE
LESDSESDGDPRERKKVKMEEEGE--QL--------ESLPQCIMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMLCECPPLSKEERAQGDVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLLSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSTNCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
AC-LKTFLE-CHGLSLLWIWMAELGDGRGSTANNLKLQLEIMKTLELLPIPNKNMLEESK
VLPIIQRWAQTKTVVPQLSEGDGYSSENTSRAHTPLNTPDPSIKQSTEGDTDTPKKLVFR
RLKIISENSMDSAISDTTSELEGKEGKEDLD-QLDTIP---AEVAEE-----QQQQEL--
------KASIDVPVDSNKPQAAELEAEPETEAKE-SSGIKLEEPIAMETPSQDEEEGVSD
VESERSQEQTDKIVDMSDVATKLLDSWKDLKEVYRIPKKSQAEKESSGCLTGDRGRDAVG
HRDQIATPKNPSQSREREPERQSQS-KEKKKRRESLSPPSSAYERGTKRPDDRYDTPAS-
SKKKVRLKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLQTLGMTSPLQYDSM--GYSAP
HHSFIGYPPGYPMQAYVDPSNPNAGKVLLPTPSLDPMCSPAA-----YEHPQTLVGHTVE
PA-------LTTPQPVPVVQHVATTMEVS----VSQYVAQSD-TVVHQEPNV-AVLPVPA
PGPVQGQSYGVWDSNQQTVT---VQQQYSPAQSQPTIYYPGQTCQTVYG-VTSSYSQTAP
PIVQGYAQPSL-QYIQGQQIYTAHPQGVVVQPTTAVTTIVAAGQPPPIQQPELVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWDSPGDDASLEHEA
EMDLGTPTYDENPMKSS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTDLE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPD------
----------------------RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLPNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----VPLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
PSSPAP-VTEPVALPHTPITVLMAA-PVPLPVDVAVRALK-EPPIIIVPESLEADTKQD-
TVSNSSEEHVTQNLNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKYSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEDYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLDMERRGKYSSKLERESKRTSENEAMKRCCSPPNELGFRRGL
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGNE
LRMINKNPEREKPGSPSPSNRLNDSPTFKKLDE----LPIFKS-EFIAHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKADAVLMTSDDSVTGSEVSP--
----LVKA---CVLSSNGFQNISRCKENDSDDTCMLHNKSES-PFRETEPLVLPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNVS-NPSLCNSEA
E-NIEPSVTKISSNSFMN--VHLESKTVISDNRNLTD-HSKF-ACEEYK--QSVGSTSSA
SVNHFDDLYQPIGSSGIASSRQSLPPGIKVDSLTLL----KCGENMSPGLDAVLKSKKSS
EFLKRAGKETIVEVGSD--LPDSGKGFASREKRHNNGLSGKC----LQEAQEEGNSVLPV
RRGRP--------EISLDE-GERGCMHTSDDSEVVF-SCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSHSYRHYSDHWEDERLESRRHSYEEKFETI-ASKACLQTDKF
F-LHKGTEKNPEISFTQSSRKQVDNH---LPELSHPQSDGVDSTSHTDVKSDHLG-HLNS
EET------VKAKISCRQ-QELPIYS-SDFEDVPSKSWQQTTFPNRPD-SRLGKTE-LSF
SSSCEISHVDGLHSSEELRNLGWDFSQ-EKPTTTYQQPDSSYGACGAHKYQQSAEQYGGT
RDYWQGNGYWDPRS-GR-PGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKFLVSL-QKDKGSVQAPEISSNSIKDTVAVNEKKD-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQE--ETSLPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSMKLSAEVDTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-PLENIP---VEEEEE-----LQSQQLLP
QQLPECKVDSETSVDASKLPTSEPEADAEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVA
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPASAYERGSKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVTQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTPP
PIVQICFLIPIKNHVLGRAWWLTP-----------------------VI-------PA-L
LEAKAGGPPEV------------------RNPISTKISQTQWDPPTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTP-------
---------------------DRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-ITEPVALPHTPVTVLMAA-PVPLPVDVAVRSLK-EPPIIVAPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIERERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKIPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFVTHDSHDSIKELDS
LSKVRNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSNNPSLCNSEA
E-NTEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSRKSS
EFLKHAGKETVVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGRVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPVEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ANKACPQTDKF
F-LHKGTEKNPEISFTQSNRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDIPNKSWQQSTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNTEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPEKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKKKIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQKKKKKTPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAK-----KKKTQPMVGHSTE
P--------LSAPKKKKKVPHVAASVEV------------SK-GVVHQDSSV-AVLPVKK
KKTVQGQNYSVWDSNQQKK--KKK-QQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLPP-Q------P-PPK---MGDFYD---P---EH-PTPEEEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEERGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTTNSPAVPLQVDSTPKIKMDLGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTARPLLATTTAVASPPS------MTVPA-AIAESTTIDSPPSSPPPP----PPPPQGTT
PSPPAP-VTEPVALPHTSITVLMTT-PVPLPVDVTVRALK-EPPVIIVPESSEVDTKQD-
TVSNSSEEHITQNLNEQADIPLQKEDSHIGKEEEIPDSSK-ISLSSKKTGSKKKSLQSEG
TFLGSESDEDSVRTSSSQRSHDIKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDARYMSSRCRSERERRRSRS--RSRSDRGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
S-SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAMKRCCSPPNELGFRRGS
-SYSKHDN-SASRYKSTPSK-PTPKSDKFKNSFCCTELNEEIK-QSHSLSLQTPCSKGSE
LRMINKIPERGKTGSPSPSNQLNDSPTFKKLDE----SPVFKS-EFIGRDSHDSIKELDS
LSKVKNDQLRSFCTI--KLNVNGSPGA-ESDLATFCTSKTDAVLTTSDDSVTGSEVSP--
----LVKA---CVLSSNGFQNISRCKEKDLDDTCVQHGKSES-PFRETEPVVSPQQDKLM
SL----SVMTIDYS-----KTVIKE-PVDM-RVSCCKTKDSDIYCTSNDS-NP-LCYSVA
E-NIEPSVMKISSNSFMN--VHLESKPVVCDNRNLTD-HSKF-ACEEYK--QSVGSSSST
SVNHFDDLYQPLGSSVIASSLQSLPPGIKVDSLTLL----QCRENTSPVLDAVLKSKKSK
EFMKHAGKETIMEVGSG--LPDSGRGFTCLENSHNNGLSGKC----LQEAQEEGNSMLPD
RRGRP--------EISLDEEGERGHAHTSDDSEVVFSSCDLNLTMEDTDG-IT--CTLKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLEPRRHSYEEKYESI-ASKACLQTEKF
F-LHKGTEKNPEISFTQSSRKQVDNH---LPEIAHPQSDGVDSTSHTDVRSDSLG-HPNS
EET------VKAKISSRQQEELPVYSSDDFEDVPNKSWQPTTFTNRPD-SRLGKTE-LSF
SSSCDISRMDGLRSSEELRNLGWDVSQQEKPTTTYQQPDSSYGACGEHKYQQSAEHYGGT
HNYWQGNGYWDPRLAGRSPGTGVVYDRIQGQVPDSLTDDREE---EENWDQRSGSHFSSQ
SSKFLLSL-QKDKGSVQAPEISSNSIKDSLAMNEKKD-FSKNLEKNDIKDRGPPKKRRQE
LESDSESDGELQDRKKVRMVIEQG--GTSVFPGS-ALIGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGQES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----FRSQQLLP
QQLPESKIDSETTMEASKLPISEPEADTEMEPQE-SNGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKESA---ITERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
SGPVQGQNYSVWDSSQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTAP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLPL-Q------P-PPK---MGDFYD---P---EH-PTPEEEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEERGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTTNSPAVPLQVDSTPKIKMDLGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTARPLLATTTAVASPPS------TTVPA-AIAESTTIDSPPSSPPPPP--PPPPPQCTT
PSPPAP-VTEPVALPHMSMTVLMTT-PGPLPVDVAVRALK-EPPVIIVPESLEVDTKQD-
TVSNSSEEHITQNLNEQADIPSQKEDSHIGKEEEIPDSSK-ISLSSKKTGSKKKSLQSEG
TFLGSESDEDSVRTSSSQRSHDIKFSASIEKERDLKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYMSSRCRSEREQRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
S-SSYSKSDRDCKAETSYLEMERRGKYSSKLERESKRTSENEAMKRCCSPPNELGFRRGS
-SYSKHDN-SASRYKSTPSK-PTPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKIPEREKTGSPSPSHELNDSPTLKKLDE----SPIFKS-EFIGPDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNVNGSPGA-ESGLATFCTSKTDAVLTTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKEKDLDDTCVQHSKSES-PFRETEPVVSPQQDKLM
SL----PVMTIDYS-----KTVIKE-PVDT-RVSCCKTKDSDIYCTSNDN-NP-SCYSEA
E-NIEPSVMKISSNSFMN--VYLESKPVVCDNRNLTD-HSKF-ACEEYK--QSVGSSSST
PVNHFDDLYQPLGSSVIASSLQSLPPGIKVDSLTLL----PCGENTSPVLDAVVKSKKSK
EFLKHAGKET-MEVGSG--LPDSGRGFICWENRHNNGLSGKC----LQEAQEEENSILPD
RRGRP--------EISLD-EGERGHAHTSDDSEVVLSSCDLNLTMEDTGGSIT--CTLKC
DSSGHAP-E---IVSTIHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLEPRRHSYEEKYESI-ASKGCLQTEKF
F-LHKGSEKNPEISFTQSSRKQVENH---LPEIAHPQSDGVDSTSHTDVKSDSLG-HSNS
EEA------VKAKISSRQQEELPVYSSDDFEDASNKSWQHTTFTNRPD-SRLGKTE-LRF
SSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGACGGHKYQQSVEHYGGT
RNYWQGNGYWDPRSAGRSPGTGVVYDRIQGQVPDSLTDDREE---EENWDQQSGSHFLSQ
SSKFLLSF-QKDKGSVQAPEISSNSIKDSLAMNEKKD-FSKNVEKNDIKDRGPPKKRRQE
LESDSESDGELQDRKKVRMEIEQG--GSSVFPGS-ALIGPSCVMDDFRDPLRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGQES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LHPQQLLP
QQLPESKIDSETPVEASKLPISEPEADTEMEPKE-SNGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
SGPVQGQNYNVWDSSQQSV--SVQ-QQYSPAQSQATIYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

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-------MEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESV-ANKACLPTEKF
F-LHKGTEKNPEISFTQSSRKQVDNH---LPETAHPQSDGVDSTSHTDVKSDSLG-HQNS
EEA------IRTKISSRQQEELPIYSSDDFEDVPIKSRQQTIFSNRPD-SRLGKME-LNF
SSCGEISRADGLHSSEELRNLGWDVSQQEKPTTTYQQPDSSFGACCGHKYQQSAEQYAGT
RNYWQGNGYWDPRLAGRPPGTGVAYDRIQGQVPDSLTDDREE---EENWDPRSGSHFSSQ
SNKFLLSL-QKDKGSVQAPEISSNSIKDSLAVNEKKD-FSKSLEKNDLKDRGPPKKRRQE
LESDSESDGELQDRKKVRVEVEHG--ETSLPSGS-ELIGPSCVMDDFRDPQRWKEYAKQG
RMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSNKLGAEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---IEEEEE-----LQSQQLLS
-QLPESKVDSETTLEASKLPTSEPEADAEMEPKE-SNGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---VTERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GFNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSAE
P--------LAAPPAVPVVPHVAAPVEVS----SSQYVTQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYNVWDSNQQSV--NVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTAIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

-------------XXXXX-X------X-XXX---XXXXXX---X---XXXXXXXEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAAPLQVELTPKIKMDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLAATPAVASPPPLT----VQLPA-VIAESTTVDSPPSSPPPP----PPPPQVTT
PLPPAP-VTQPVVLPHTPVTVLMTA-PVPLPVDVAVRALK-EPPIISVPESLEVDTKQD-
TVSNSSEEHITQNLNEQADILSKKEDSHIGKEDEIPDSSK-ISLSSKKTSSKKKSLQSEG
TFFGSESDEDSVRTSSSQRSHDLKFSASIEKEREFKKSSATLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTENRTRESSDSEEDYKKTYSRRT------SSHS-SSYRDLRT
S-SSYSKSDRDCKTEISYLEMERRGKYSSKLERESKRTSENEAVKRCYSPPNELGFRRGS
-SYSKHDN-SASRYKSTPSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMISKNPEREKTRSPSSSNQLNDSPTFKKLDE----SPVFSP-EFIGPDSHDSIKEFDS
LAKVKNDQLRS-CPI--ELNINGSPGA-ESDLATFCTSKTDAVLVTSNDSVTGSEVSS--
----LVKA---CIRSSNGFQSVSRCKEKDLDDTCMQHSKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDM-RVSCCKTKDADTYCTSNDS-ISSLCYPET
E-NTEPSVMKISSNSFMS--VHLESKTVICDNRNLTDQHSKF-SCEEYK--QSIGSTSSA
SVNHFDDLCQPIESSGIALSLQSYPPEIKMDSLTPL----KCGENTSPVLDAVMKSKNNT
EFMKHAGKETI-EVCSG--LPDSGKGFTSWETRHNNGLSGKC----LQEAQEEGTSILSD
RRGRP--------ETSLDEEFERGHVHTSDDSEVVFSSCDLNLTTEDSDS-VT--YTLKC
DSSGHAP-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEEERLESRRHSYEEKFESI-TSKACLQTEKF
F-FHKGSEKNPDISFTQSSRKQVDNH---LPEIAHSQSDGVDSTSHTDVKSDLLG-HPNL
EET------IKAKISSRQQEELAIYYS-DFEDVPNKSWQQTTFPNRPG-SRLGKTE-LSF
PSSCEISCVDGLHSSEELRNLGWDFSQ-EKPTTTYQQPDSSYGTCG-HKYQQSAEQYGGP
HNYWQGNGYWDPRSAGRPPGAGIVYDRTQGQVPDSLTDGREE---EENWDQRGGSHFSSQ
SSKFLLSL-QKDKGSVQAPEISSNSIKDSLAVNERKD-FSKNLEKNDIKDRGPPKKRKQE
LESDSESDGEPQDRKKVRMEIEQG--ETTLPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHANVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSRQLLP
QQLPDSKVDSETSTEASKLPTSEPEADTEIESKE-SNGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAIG
FRDQTATPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHSFAGYPPGYPMQAFVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHTQPLVGHSTE
P--------LSAPPPVPVVSHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYGVWESNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTPPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

---------------------------------------------------PLGLQAHAA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-ITEPVALPHTPVTVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIERERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDSIKELDS
LSKVRNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTINYS-----KTVVKE-PVDT-RVSCCKTKDSDTYCTSNDSNNPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCGENTSPVQDAVLKSRKSS
EFLKHAGKETVVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGRVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPVEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ANKACPQTDKF
F-LHKGTEKNPEISFTQSNRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDIPNKSWQQSTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEVS------------NYSCEPLC---PWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPEKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAASVEVS----SSQYVAQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

MSKDPSGHHNPNTSSIPEMHS-----PLRWK---GADNWCIFPQNMDGSEEVEREEENEG
KGDNLQKPGFVKGPVFKGIASSRFLPKGTRTKVNLEEQGRQKVSFSFSLTKKTLPNRFLA
GLGNDKQNETSGSPAAAPPTDLASKIKMDLVDSPSAVEEFSPPKPKVELGRIHFKKHLLN
VTTKLPLAVAAALPPPPPPPPPPALQAPAD---AFEMVELPPSPPPPPPPPPPPPPP-QM
VSTPAT-VLTPPALSQIPSTPVP---PLPPSPVETIVQMTKVPSLKTSQETSEADVQENS
SVLNVSIEHLPEAVSDEAEPTPTKGHSHNGKEEEVSDGSKVAPQSSKKQGSRRKFSLSDV
PAPGSESDEDSVRTSSSQRSHDIKLPTSSEKEKDSRKSSSSHKTEAPSKTSSRSKSDRDE
KYSSYSRSERDSRYSSSRSRADRERRRSRSRSRSRSERSSRPSSSYSRSERSHYYDSDRR
HHRS-SPYREKSRYSRSYTDSRTRESSDSEEEYRRSYSSRSTDSRRTSSHS-SSYRDSRT
S-SSYSKSERESRTESSHTESDRKGKST-KSERESRRTSETDGSRRC-SPTGESRHRSGA
SHSKADSSVTSSRHKPTSSKTSVPRPDKFKSSFCCTESEE-VKEQSNCIDSEASCVQSCE
IKTAV-PPKPETDRTVSPLSPLRDSPSFKKLEESKEGSPISKSNELAGIDSHDSIKEVDS
FVTVKHDITLTTCSTRTETNLNGSPESTQNDTAVFCNSEPEVT-VSSDNSLDRSDSLDTF
EAQSQIKSPHLNKTPSNGVQSVSPSKEQALGDSLLLSSESICLPIKKEEVLILSEYE---
----CVPSCTENVN-----LSEITQNVDDQ-TDPCNQAKDPVPCYLSDD--ATPLYYSEV
EIEAEPSDAKAAPGSFTDVNVEPCIETL--KSSDVEDQNSLGCAHEGEK-----------
CLKQFNSIES---SPARDSSMEESLVNMELDNQCVAEQQQQTCENGSLELETTLQEK-EE
EVLECSE--VALELDVLQVESAIEKTTSPLKNEHSYYLERSIQDPEKEEPNGDEDSLALD
ERATS-GLDDCSPEVFVMKD---ESSVVESDFPGALSPCDILVAEEETET-VP--EVTRC
DSSRSNP-E---LTPVHNEDYSDLAESGSEQGS-DESDTEDSDSDDSSIPRNRLQSVVVI
PKNSTIAMEESSSCSSRNSQSNRRYLDRWEEARPESSKSFYEDAPNDL-EAGHALQNERK
CLSSRDMEGNLAIS-AEPSRMEMADL---QPRISQPQSDDVDSTSQSDQASDSIGKPNPE
ERVALSETMSLARFVGESQEHELHYFPRNFEMTDHMSRLQTSIS-KPD-SQQGKPCFGDL
PGPGGLSREDGFHSTE-----EWDFSQAEKPSSTYQQPDSSYGIYPGYVYPPNSGPYVGS
HSYWHDNGYWDPRLTHRP--CEMNYERMQGPVPDSLTEDHEEYEEVDHWVDEGQAYFPSQ
SVKYPS-RDPREKGSVQAHEISSNSVKEPVAASEQKEQASKALDRNDMKERGPLKKRRTD
LESESESDGDSQERKKAKTEGEPL---PAVPQGDSLGEGLLCYMEDFRDPQRWKEFAKHG
RMPCYFDLIEENVYLTERKKNKSHRDIKRMLCECPTLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGEHCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKTRVKEYARSKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKMVPSGSELTFD YQFQRYGKEAQKCFCGSTNCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALLENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
AC-LKTFLE-SHGLSLLWIWMTELGDGRGNTANNLKLKLEIIKTLELLPIPNKNMLEESK
VLPIIQRWAQTKLAIPHLSEGDGYSSENTSRAHTPLNTPDPSAKPSTEVEADTPKKLAFR
RLKIISENSMDSAASDTISEVELKDGKEEPPEHLDSAPMETVAEEEP-----VQAEDVVK
DAAPEAPADP------NQPQAAEQEPEPEVEMKEIIIAAKMEEPVAGETPSQDEEEGLSD
VESERSQEQTDKIVDVSDLATRLLDCWKDLKEVYRIPKKSQVEKETT----ADRGRETAG
R-DP--ASTPKNLSRERDPERQSQS-KEKKKRRDSLSPP-SAYERGTKRPDDRYDTPAAS
SKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQLQSLGMASPLPYDPL--GYSAA
HHAFMGYPPGYPMQSYVDPSNPNAGKVLLPTPSLDPMCSPAA-----YDHSQTLVGHPIE
TT-------LAAPQPVPVVQHVAAALEVP----APQYVAQGD-SVVHQDTSG--VTVLPV
SAPVQGQSYGVWDSGQQTVA---VQPPYSPAQTQPAIYYQGQACQAVYG-VTSPYSQTAS
PIVQSYAQPGL-QYIQGQQIYTA--QGVVVQPTTAVTTIVAAGQPPPIQQPELVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVATRQTQWDP PNWDSPEDDASLEHEA
EMDLGTPTYDENPMKSS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRINTTE--DFKHLARKLTHGVMNKELKYCKTPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTDLE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------TEKRGKYSSKLEREFKRTSENEVIKRCCSPSNDLGFRRGS
-SYSKHDS-SASRYKATPSK-PITKSDKFKNSFCCTELNEGIK-QSHSFSLQTPCSKGSE
LRMINKIPEREKARSPSPSDQLNDSPTFKKLDE----SLIFKS-EFIGHDSHDSIKELDS
LSKGKHDKLRTYCPV--ELNINGSPGP-ESDLATFCTSKE-TVFMSSDDSVTGSEVSP--
----LTKA---CMLSSNGFQNINRCKEKDVDATCMQHSKSES-PFPETEPALSPHQDKPM
TL----PGMATDYS-----KTALKE-PVDT-RLSCCKTKDSDIYCTSNDS-STSLCHSEA
E-NSEPSVMKISSSSCMN--VHLESKTTVCDNRNLTDQNSKF-ACEEYK--QSVGSTSSA
SVNHFDDLCQPVGSSHVASSLQSLPPGIKVDCFTVL----RCGENTSPVLDAVLMSKTST
ELLKHAGEQ-TVEVGSG--LPDSRRGFSSWENRHNNGLSGKC----LQETQ-EGNAVLPD
RRGRP--------EISLGE-GGRRHVHASDDSEVVFSSCDLNLTMEDSDG-LT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFEVI-TNKTCPQTEKF
F-LHKGSEKNPEISFTQSSRKQVDNH---LPDSAHPQSDGVDSTSHADVKSDPLG-HSHS
EEI------VKVKIASRQQEELPVYSSDDFEDAPNKSRQQSTFPHRPD-SRLGKTE-LSF
SSSCETSLVDGFHSSEEVRNFGWDFSQPEKPTTTYQQPDSSYGACGGHRYQQSAEQYGGT
YGYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTEDHEG---EENWDQRDGSHFSSQ
SNKFLVSIQQKDRGSVQAPEISSNSIKDSLAVNEKKD-LTKNLEKNDMKDRGPLKKRRQE
LESDSESDGELPDRKKVRVEMEQG--ETAAPSGS-GLIGISCVMDDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERK--RSHRDIKRMQWKCA-LSKDERA-QEIACGEDCLNRL--M
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAARDLPSNTFVLEYCGEVLDHK
EFKARVXXXXXXXXXXXXXXXXXXXXIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-XXXXXX-XXXXXXXXXXXXXXXXXXXX---XXXXXXXIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLTMEADTETPKKLMVR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQP-----
QQLPESKADGEAAMEVSKLPISEPEADTEIEPKE-SNGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTADISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITER-RDAAG
CRDQSAAPKTPNRSRERDPEKQIQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPTP-----YDHSQPLVGHSAE
P--------LAAPPPVPVVPHVTTPVEVS----SSQYVAQSD-SVVHQDSSV-AVLPVPA
PGPVQGQNYGVWDSNQQSVS-SVQQQQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXPEMIVTNN-L
LDLPPPSPPKPKTIV LPPNWKAARDPEGKIYYYHVVTRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPD------
----------------------RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
LSSPAP-VTEPVALPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
IFLGSESDEDSVRTSSSQRSHDLKISASIEKERDFKKSSAPLKSEDLG-KSSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGSRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEIERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----LPIFKS-EFITHDSHDSIKELDS
LSKVKNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLITSDDSVTGSELSP--
----LVKA---CMLSSNGFQNISRCKEKDLDDTCMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTVDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTLNDS-NPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSKKSS
EFLKHAGKETIVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPE
RRGRP--------EISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSGSSESSND-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESI-ASKACPQTDKF
F-LHKGTEKNPEISFTQSSRKQIDNH---LPELSQPQSDGVDSTSHTDVKSDPLG-HPNS
EET------VKAKIPSRQQEELPIYS-SDFEDVPNKSWQQTTFQNRPD-SRLGKTE-LSF
SSSCEIPHVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGACGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKFLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKD-FSKYLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETLVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKVDSETNIEASKLPTSEPEADAEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TTERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKAS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLVTTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-ITEPVALPHTPVTVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIERERDFKKSSAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDSIKELDS
LSKVRNDQLRSFCPI--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----QVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSNNPSLCNSEA
E-NIEPSVMKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSRKSS
EFLKHAGKETVVEVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLQERGEGGRVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YALKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPVEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ANKACPQTDKF
F-LHKGAEKNPEISFTQSNRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDVPNKSWQQTTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSL-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLADKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---IEEEEE-----LQSQQLLP
QQLPECKVESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPLNEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRGSVSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAASVEVS----SSQYVAQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPAVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------EEENEA
KIENVPKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPVVPLQVDSTPKVKTDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLTATTAVASPSPPM----APLPA-VRAESTTVDSPPSSPPPP----PPPPQATT
PSSPAP-VTEPVALPHTPVTVLMTA-----PVDVAARALK-EPPVTIVPESSEVDTKQD-
PVSNSSEEHITHSLNEQADIPSQKEDSHIGKEEETPDSSK-SSLGSKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSANIDRERDSKKSLATLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRE-RERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRAYTDSRARESSDSEDEYKKTYSRRT------SSHS-SSYRNLRT
S-SSYSKSDRECKTESSYLETEKRGKYSSKLERESKRTSENEAMKRCCSPPNELGFRRGS
-SYSKHDN-NASRYKSAPSK-PVSKSDKFKNSFCCTELNEETK-QSHSFSLQTPCSKGSE
LRVISKIPEREKTRSPSPSNRLNDSPTFKKLDG----SPVFKS-EFIGHDSHDSIKEVDS
LCKVKNDQLRSYCPT--ELNINGSPGA-ESDLAAFCTSKHDTVLMSSDDSVTGSEVSP--
----LVKT---CMLSSNGFQNINRCKEKDLDDTCMKHSKSES-PFRETEPLVSPHQDQLI
SL----PVMTMDYS-----KTVVKE-PVEV-RVSCCKTKDSDIYCTSNDN-HPSSCHSGA
E-NIEPLVTKMSSNSFMN--VHLKSKTGICDNGNLIDQHSKF-ACGEYK--QSVGSTSSA
SVNHFDDLYHTPGSSCIASSLQSLPPGIKVNSLTLL----QCGENISPVLDAVPKSK-NS
EFLKHAEKETVIEVGSD--LPDSGRGFASWDNRHNNGLSEKC----VQEAHKEGNSLLPD
RRGRP--------EISLDEEGGRGHAHTSDDSEVVFSSCDLNLTMEDSDG-IT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLTMEETSPCSSRSSQSYRHYSDHWEDERLEPRRHSYEEKFESI-TSKACPQTEKF
F-FHKAAEKNSEISFIQPSRKQIDNH---LPEIAHPQSDGVDSTSHPDIKSDPLG-HSNS
EET------VKAKIVSQQQEELPVYSSDDFEDVSNKSRQQTTFPNRPD-SRLGKTD-SSF
S-SCEISRVDGFRSSEELRNLGWDFSQQEKPTTTYQQPDSSYGACGGHKYQQSAEQCSGA
RSHWQGNGYWDPRSASRPPGAGVVYDRIQGQVPDSLTDDREE---EENWDQRGGSHFSSQ
SSKFFLSL-QKDKGSVQAPEISSNSIKDSLAVNEKKD-LLKNLDRNDMKDRGPLKKRRQE
LESDSESDGELQDRKKVRMEIEQG--ETAVPLGS-ALVGPSCVMEDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAIPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSAEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---IEEEEE-----PQPQHLLV
QQLPEPKVDSDVAAEASRLPTSELEADAELEHKE-SSGAKLDEPIAEETPSQDEEEGVSD
VESERSQDPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---ITERGRDAVG
FRDQTVAPKTPNRSRERDPDKQTQI-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYSAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAA-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-TVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQACPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------TEKRGKYSSKLERESKRTSENDVTKRCCSPSSELGFRRGS
-TYSKHDNNSASRYKSASLK-SVSKSDKFKNSFCCTELNEELK-QSHSSSLQTPCSKGSE
VRMISKIPEREKTGSPSASSQMNDSPTFKKLDE----LPIFKS-EFIGHDSHDSIKELDS
LSKVKSDQLRSYCPI--ELNVNGSPGA-ESDLTTLGTSKADTVVMSSDDSVTGSEVST--
---PLVRA---RMLSSNGLQNISRCQEKDLDDTCTQYSKSES-PFKERDLPASPYQENFM
PL----PVMTTDCS-----KTVVQE-PLDG-RVSFSQAKDSDMYIASNDS-NPNLCHSES
E-NIEPSVATVSSNSFMN--VHLKSETIVCDSRNLTDKHSEF-LCEEYK--RSTGSTDSS
SVSHLDDLYQPIGSSRVASPLPSLAPRVKVDSLAVL----QCGEDTSPILDPVLKNK-SS
ESVKLADQEAAVEVACD--LPDSARGFASWENRHNNGLAGKC----VQENQEGGNSLLSD
RRGKP--------ELSLD-EGRRGHARTSDDSEIVFSSCDLNLNVEDSDS-VT--YTLKC
DSSGHAS-E---IVSTVPEDYSGSSESSGD-----DTDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSQSSQSYRHYSDHWEDERLESRRHSYDEKIESL-ASKSCPQADKF
F-FHKGIEKNPEVSFTQSTRKQIDSH---LSEVALPQSDGVDSTSHTDGGSDPRS-HPNS
EER------AKAKITSRQQEELPVYSPDDFEDIPNKSRQQSTFSNHPDS-RPRKTQ---S
SFACEISRVDSFRAPEELRNLGWKFSQQEKPTTTYQQPDSSYGVCAGHKYQHSAEQFGGA
HSYWQGNGYWDPRSAGR-LGTEVAYDRIQGQVPDSLTDDREE---EEGWDQRGGPQFSSQ
SSKFFLSL-QKDTGSVQAPEISSNSIRDTA-ASEKKE-FSKTLEKNDMKDRGPPKKRRQE
LESDSESDGELQARKKVRAEEEEGQAEMAAPPGS-ALAGPSCVMEDFRDSQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECAPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHAAVEVILTEKKGWGLRAARDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKXXXXXXXX
X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX---XXXX-X-------XXXXXX
XXXXXXXXXXXXXXXXXXXXX----XXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNERGRD-AG
FRDQTAAPKTPNRSRERDPDKQSQN-KEKRKRRGSLSPPSSAYERSAKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQ--QQMQNLRMASPLPYDSL--GYPAS
HHPFVGYPPGYPMQAYVDPSNPNAGKVLLPTPSLDPVCSPAP-----YEHAQPLVGHSTE
A--------LAAAPTVPLVSHVAASVEVS----SSQYVAQSD-ASVHQESSV-AVLPVQT
PGPVQGQNYGVWDNGQQPVS---VQQPYSPAQSQ-TIYYQGQTCPAVYG-VTSPYSQTAA
PVVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPATAGTAVVAPGQPQPLQPPDMVVTNS-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTA EADTSSELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------EEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALSNEKQSDSPNSPATPLQVDSSPKAKMDTGDTFPTTEESSPPKSRVELGRIHFKKHLLH
VTSRPQLATA----TSPPPT----IQLPA-VIAES-TVDSPPSSPPPP----PPPPQATS
PSPPAST-SEPVALPHPPVTVPMTAPVPL-----PVDSAQKEPPIKIVPESLEVGMKQD-
IVSNSLEEHTIQTLREQADNPLQREDSHIGKEEEVSDGSK-TSLSSKKASSKKKSSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIEKERDFKKSSAPSKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYVSSRCRSERDRRRSRS--RSRSDRVSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRT------SSH---SYRDLRT
S-SSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSDHEAIKRCCSPPTELGFRRGS
-SYSKHDN-SASRYKSALSK-PVSKSDKFKNSFCCTELNEENK-QSH-FSLQTPCSKGSE
LRTSNKIPEREKTGAPSPSNQLNDSPTFKKLDE----SPILKR-EFTEHDSHDSIKELES
LSKVKNDQLRSFCSI--ELNINGSPET-ESDTVTFCASKTDAFSLTSDDSVTGSEVSP--
----LIKA---CMLSSNGFQNIGRCKEDDSDDTYRQHNKSQS-PFRETEPLLLPHHDKLV
SL----PVKTIDYP-----KTLIKD-PVDK-RRSCCKTKDSDRYCSPNEN-------SEA
E-NPETSVVKISSNSFMN--VHLESEIVLCDNTELTDQHSKC-ACDEYK--QSIGSTGSA
SLNHFDDVYESVGSSGIVS---SLPSGV------------RCEENTSPVLDAVQ-SKKST
EFLKYAGKETEVG--S-A-LPDSAKGFASWENRYNNVLSGQS----LQEAQEEGNSILHD
RRGRT--------EISLDEEEGRSRTHTSDDSEVVFS-YDLNLTMEDSDS-IT--YTLKC
DSSGNIP-E---I-STVHEDYSASSGSSSE-----ESGSEDTESDDSSVPRHRLQSVVVV
PKNSTLPMEETSPCSSRSSHSYRHYSDHWEDERLESRRHSYEDKFENM-TSKGCPQTEKF
F-LHKGTERNPE-TYSQFSRK-VDNH---LPEIAHSQSDGVDSTSHTDLKSDSLG-HLNS
EDT------VRAKTSRSQ--ELPVYSSDDFEDIPNKSRQQMIFSNRPDSSRLGKTE-VNF
S-SCDISHMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGACGTHKYQQSAEHFAGT
HSYWQGNGYWDPRSAGRPTGTGVAYDRIQGQVPDSLTDDRE----EESWDQRSGSHFPSQ
SSKFLFH--QKDKGSVQAPEISSNSVKDTLVPNERKE-FSKNFEKNDIKERGPPKKRRQE
VESDSESDGELQARKKMRVESEPG--ETSVLLQS-ELMGPSCAMEDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSIKLSTEVDTETPKKLVFR
RLKIISENSMDSAISDVTSELECKDGKEDLD-QLETVT---VEEDDD-----LQSQQLLP
QQPCESKVESETTIEVSKLPTSEPEADTEAELKE-SSGTKLEETIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VTERGRDAAA
FRDQT-VPKTPNRSRERDPDKPTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPFDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTE
S--------LAAPASVPVVPHVAASVEVS----SSQYVAQNE-SVVHQDSSV-PVMPVQA
PGPVQGQNYSVWDSNQ-QSV-SVQ-QQYSPAQSQATIYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYAQPNL-QYIQGQQIFTAHPQGVVVQPTSAVTTIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDANLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKPLPSQQ------P-PPK---MGDFYD---PEH----PTPEEEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSFTKKTLQNRFLT
ALSNEKQSDSPNSPAPPLQVDSNPKVKMDAGDTFPATEESSPPKSRVELGRIHFKKHLLH
VTSRPQLAASTTAASPLPPT----TQLPA-VLAES-MIDSPPSSPPPP----PPPPQAST
PSPPAQ-ISEPVALPQPPATALMTSPPGPLPGDVAVRAQKESLVKKSGPEVLEVDTKQD-
IVSNSLEEHTVQTLKEQADHLLQKEDSHIGKEEEVSDGSK-ISLSSKKASSKKKSSQFEG
TFLGSESDEDSVRTSSSQRSHDLKSSTSIDKERDFKKSSAPSKSEDLG-KSSRSKTERDD
RYCSYSKLERDTRYVSSRCRSERDRRRSRS--RSRSDRASRTSLSYSRSERSHYYDSERR
YHRS-SPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRT------SAH---SYRDLRT
S-SSYSKFDRDCKTETSYLEMERRGKYSSKLERESKRTSEHETIKRCCSPPNELGFRRGS
-SYSKHDN-STSRYKSALSK-SISKNDKFKNSFCCTELNEENK-QSHSFSLQTPCSKGSE
LRTINKISEREKTGSPTPSNQLNDSPTFKKLDE----SPVLKP-EFIGHDGHESIKELE-
LSKVKNDQLRNFCSI--ELNVNGSPET-EADVATFCTSKTDAVSMTCDDSVTGSEVSP--
----LIKA---CMLSSNGFQNVGRCRERDSDDTCRQHNTSKS-PFREMEPLLSPHHDKLM
SL----PVKTIDYP-----KTLIKE-PADK-RHSCCKTKDSDRYCSPNEN-------PEA
E-NTEPSVMKISSNSFVN--VHLESKTVTCDNREPTDQHSEN-TCDEYK--QNIGSTSSA
SHNHFDGLYEPIGSSGI-SSLQSPPSGI------------RCEENTSPTLDAVE-SKKGI
DFLKYARKETDVG--S-A-LPDSGKGFS-WENRHNNVLSGQS----LQEAQEEGNSILHE
RRGRP--------EIPLDEE-QRGHTHISDDSEVVFP-YDLNLTMEDSDG-IT--YTLKC
DSSGNAP-E---IVSTVHEDYSGSSASSSD-----ESDSEDTESDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYKHYSDHWED-GLETRRHAYEEKYE----SKGCSQTEKY
F-LHKGTERNAETCYSQFGRK-ADNH---LPDIAHSQSDGVDSTSQTDSRSDHLG-HLNP
EDT------LRAKTSRPQ--ELPVYS-DDFEDLPNKSRQQMIFSNRPDSSRLGKTE-LSF
SSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGTCGTHKYQQSTEHYGGT
HNYWQGNGYWDPRSAGRPPGTGLAYDRIQGQVPDSLTDDREE---EEHWDQRSGSHFSSP
SNKFFFH--QKDKGSVQAPEISSNSIKDSLVMNERKD-FSKNFEKNDIKERGPPKKRRQE
LESDSESDGELQARKKVRVEVEQG--ESSVPQHS-ELMGPSCAMDDFRDPQRWKEFAKLG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSAKPSTEVDTDTPKKLIFR
RLKIISENSMDSAVSDVTSELECKDGKEDLD-QLETVT---VEEDEE-----LQSQQLLP
QQLCESKVESEATIEVSKLPTSEPEADMETEPKD-SNGTKLEETIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---VAERGRDAAA
FRDQT-APKTPNRSRERDPDKQPQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPFDSL--GYNAS
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPLVGHSTD
S--------LAAAPSVPVAPHVAASVEVS----SSQYVAQNE-SVVHQDSNV-PVMPVQA
PGPVQGQNYNVWDSNQQQSV-SVQ-QQYSPAQSQTTIYYQGQTCSTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPSAAVTSIVAPGQPQSLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

-----------------------------MI---YFLFFC---M--LSWLDDNREEENEA
KIENVPKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPVVPLQVDSTPKVKTDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLTATTAVASLSPPM----APLPA-VIAESTTVDSPPSSPPPP----PPPPQATT
PSSPAP-VTEPVALPHTPVAVLMTA-----PVDVAARALK-EPPVTVVPESSEVDTKQD-
LVSNSSEEHITHSLHEQADIPSQKEDSHIGKEEETPDSSK-SSLGSKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSANIDRERDSKKSLATFKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRE-RERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRAYTDSRARESSDSEDEYKKTYSRRT------SSHS-SSYRDLRT
S-SSYSKSDRDCKTESSYLEIEKRGKYSSKLERESKRTSENEAMKRCCSPPNELGFRRGS
-SYSKHDN-NASRYKSAPSK-PVSKSDKFKNSFCCTELNEETR-QSHSFSLQTPCSKGSE
LRVISKIPEREKTRSPSPSNRLNDSPTFKKLDG----SPVFKS-EFIGHDSHDSIKEVDS
LCKVKNDQLRSYCPT--ELNINGSPGA-ESDLAAFCTSKHDTVLMSSDDSVTGSEVSP--
----SVKT---CMLSSNGFQNTNRFKEKDLDDTCMKHSKSES-ASRETEPLVSPHQDQLI
SL----PVITIDYS-----KTVVKE-PVEV-RVSCCKTKDSDIYCTSNDN-HTSSCHSGA
E-NTEPLVSKMSSNSFMN--VHLKSKTVICDNGNLTDQHSKF-ACGEYK--QSVGSTSSA
SVNHFDDLYQTPGSSCIASSLQSLPPGMKVNSLTLL----QRGENISPVLDAVLKSK-NS
EFLKHAEKETVIEVGGD--LPDSGRGFASWDSRHNNGLSEKC----VQEAHEEGNSLLPD
RRGRP--------EISLDEEGGRGHAHISDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLTMEETSPCSSRSSQSYRHYSDHWEDERLEPRRHSYEEKFESI-TSKSCPQTEKF
F-FHKAAEKNSEISFIQPSRKQIDNH---LPEIAHPQSDGVDSTSHPDIKSDPLG-HSNS
EEM------VKTKIASQQQEELPVYSSDDFEDVSSKSRQQTAFPIRAD-SRLGKTD-SSF
SSSYEISRMDGVRSSEELRNLGWDFSQQEKPTSTYQQPDSSYGACGGHKHQQSAEQCSGV
RSYWQGNGYWDPRSASRPPGAGLVYDRVQGQVPDSLTDDREE---EENWDQRGGSHFSSQ
SSKFFLSL-QKDKGSVQAPEISSNSIKDSLAVNEKKD-LLKNLDRNDMKDRGPLKKRRQE
LESDSESDGELQDRKKVRVEIEQG--ETAVPLGS-ALVGPSCVMEDFRDPQRWKEYAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAIPQLSEGDGYSSENTSRAHTPLNTPDPSTKLNAEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---IEEEEE-----PQPQQLLV
QQLPEPKVDSDIAAEASKLPTSELEADAEIEHKE-SSGAKLDEPIAEETPSQDEEEGVSD
VESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKEST---ITERGRDAVG
FRDQTVAPKTPNRSRERDPDKQTQI-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAA-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-AVVHQDSSV-TVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQACPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQPLQPPEMVVANN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVVTRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------MKQLQP-Q------P-PPK---MGDFYD---P--EH--PTPEEEENEA
KIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
VLGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTAVASPPTHA----APLPA-VIAESTTVDSPPSSPPPP----PPPAQATT
PSSPAP-VTEPVVLPHTPITVLMAA-PVPLPVDVAVRSLK-EPPIIIVPESLEADTKQD-
TVSNSSEEHITQILNEQADISSKKEDSHIGKDEEIPDSSK-ISLSCKKTGSKKKSSQSEG
TFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLG-KSSRSKTDRDD
KYFSYSKLERDTRYVSSRCRSERERRRSRS--HSRSERGPRTNLSYSRSERSHYYDSDRR
YHRS-SPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-SSYRDLRT
--SSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAVKRCCSPPNELGFRRGS
-SYSKHDS-SASRYKSTLSK-PIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMINKNPEREKAGSPAPSNRLNDSPTLKKLDE----FPIFKS-EFITHDSHDSIKELDS
LSKVKNDQLRSFCPT--ELNINGSPGA-ESDLATFCTSKTDAVLMTSDDSVTGSEVSP--
----LVKA---CMLSSNGFQNISRCKGKDLDDTRMLHKKSES-PFRETEPLVSPHQDKLM
SL----PVMTIDYS-----KTVVKE-PVDT-RVSCCKTKDSDIYCTSNDSSNLSLCNSEA
E-NIEPSVIKISSNSFMN--VHLESKPVICDSRNLTD-HSKF-ACEEYK--QSIGSTSSA
SVNHFDDLYQPIGSSDIASSLQSLPPGIKVDSLTLL----KCGENTSPVLDAVLKSRKSL
EFLKHAGKET--EVGSD--LPDSGKGFASRENRRNNGLSGKC----LQEAQEEGNSILPD
RRGRP--------EISLHERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAP-E---IVSTVHEDYSDSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESI-ASKACPQTDKF
F-LRKGTEKNPEISFTQSSRKQIDNH---LPELSHPQSDGVDSTSHTDVKSDSLG-HPNS
EET------VKAKISSRQQEELPIYS-SDFEDVPNKSWQQTTFQNRPD-SRLGKTE-LSF
SSSCEISRVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGTCGGHKYQQNAEQYGGT
RDYWQGNGYWDPRS-GRPPGTGVVYDRTQGQVPDSLTDDREE---EENWDQQDGSHFSDQ
SNKYLLSI-QKDKGSVQAPEISSNSIKDTLAVNEKKE-FSKNLEKNDIKDRGPLKKRRQE
IESDSESDGELQDRKKVRVEVEQG--ETSVPPGS-ALVGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLCRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTDADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLP
QQLPECKLESETNIEASKLPTSEPEADTEIEPKE-SNGTKLEEPINEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---TAERGRDAVG
FRDQTPAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHAQPMVGHSTE
P--------LSAPPPVPVVPHVAAPVEVS----SSQYVTQSE-GVVHQDSSV-AVLPVPA
PGPVQGQNYSVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSELA KKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------------
--------------MFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDAPNSPAVPPQADSTPK--MDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLATTTVVASPTPPT----ITLPA-VIAESTTADSPPSSPPPP----PPPPQAII
PSPPAS-VTEAVALPHTPF--LMAA-PVPSVVDVAVRALK-EPPVTIIPESLEVDTKQD-
IVFNSSEEHITQHLNEQADIPSQKEDSHIGREEEIPDSSK-TSLGSKKTGSKKKSSQSEG
TFLGSESDEDSVQTSSSQRSHDLKFSAGIEKERDSKKSLAPLKSEDLG-KSSRSKTERDD
KYFSHSKLERDTRYISSRCRSERERRRSRS--HSRSDRSSRTSLSYSRSERSHYYDCDRR
YHRG-SPYRERVRYSRTYADNRARESSESEDEYKKTYSRRT------SSHS-TSYRDLRM
--SSYSKSDRDCKTESSYLETEKRGKYSSKLERESRRTSENEVMKRCCSPPNELGFRRGS
-SYSKHDN-SASRYKSAPSK-PIPKSDKFKNSFCCTELNEETK-QSHSFSLPTPCSKGSG
LRLISKIPEREKTGSPSPSNQLNDSPTFKKLDE----SPPFKS-EFIGHESHDSIKELDS
LSKGKHDQLRTYCPI--EVNINGSPEA-ESNLATFCTSKTEAVLMSSDDSVTGSEVSP--
----LVSA---CILSSNGFQNISRCKEKDLDDTCMQHSKSES-PFRETEPPVSPHQDKLT
LSVMTGSYDFPSYS-----KTVVKE-PDET-RVSSCKTKDSDTYCTSNDS-IPSLCHSEA
E-NIETSLTKISSNSFMN--DHLESKTVICENRSLTDQHSKF-ACEEYK--QSVGSTSSA
SINHFDDLYKPTGSSGIGSSLQSLPPGIKVDSLTLL----QCGENTSPVLDAVLKGKNTT
GFLKHAGKETIVEMDSG--LPDSGRGFASWENRNNNGLSRKC----LQETQEEGNSNLPD
RRGRP--------EISLDEEGGRGHVHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHTS-E---IVSTIHEDYSGSSESSSD-----ESDSEDTDSDDSSIPKNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERPESRRHSYEEKFEGI-ISKTCPQTEKL
F-LHKGMEKNPEISFTQSSRKQVDNH---LSEIAHSQSDGVDSTSHTDVKSDILG-HPNS
EET------VKVKIAFRQQEELPIYSSDDFEDVPNKSWQQTTFPNRPD-SRLGKTE-LTF
SSSCEISRVDGFHSSEKLRNLEWDFSQPEKPTTTYQQPDSSYGVCGGHKYQQNAEQYGGV
CNYWQGNGYWDPRSAGRPPGTGVVYERIQGQVPDSLTDDRGE---EENWDQRGGSVFSNQ
SSKFPLSL-QKDIGSVQAPEISSNSIKDSLAMNEKKD-LSKNLEKNDMKDRGPPKKRRQE
LESDSESDGELQDRKKVRVEVEQR--ETIAPPGS-VLLGPSCVMDDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAARDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKIAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKMITEADTDTPKKLMFP
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQPQQVLT
QHLPECRIDNETAVDGSKLPTAEPEVDAEIEPRE-SNGTKLEEPIAEETASQDEEEGMSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---VSERGRDAVG
FRDQTAVPKTPNRSRERDPDKQAQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRSKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYSAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPNMDPVCSPAP-----YDHAQPLVGHSAE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVSQSD-GVVHQDSAV-SVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTAIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKVLLASG--LSVFCAN--------CLLSKKAPFITESVF
SLPQVPGTGMEGGGEGGEEHHLT

------------------------------------------------------------
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------------------------------PERESKRTSENEVMKRCCSPHNELGLRRGS
-SYSKHDS-SASRYKSVPSK-PIPKSDKFKNSFCCTELNEDTK-QSHSFSLQTPCSKGNG
LRMISKIPEREKTGSPSPSNQLYDSPTFKKLGE----SPLFKS-EFIGHESHNSIKELDS
LSKGKHDQLRTYCPI--ELNMNGSPGT-ESDLATFCTSKTEGVLMSSDDSVTGSEVSP--
----LVKP---CMLSSNGFQNISRCKEKDLDDSCLQHSKSES-PFREKEPPVSPHQDKLV
SL----PVMTSSYDFPSDFKTVVKE-PADL-RVSSCKTKDSDIYCTSNDS-NPSTCHSEA
E-NIEPSVMKISSNSFMN--VHLESKTVLCDNRNLTDQHSKF-VCEEYK--QSVGSTSSA
SIYHFDDLYQSTGSSGTVSSLQSLPPGMKVDSLTLL----QCGENTSPVLDAVLKNKKST
EFLKHAGKET-IEVGSG--LPDSRRGFASWESRHNNGLSRKC----FQEAQEEGNSDLPD
RRESP--------EISLDEEGGRGHVHTSDDSEVVFSSCDLNLTMEDSNG-IT--YTLKC
DSSGHAS-E---IVSTIHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLELRRHSYEEKFEGI-ANKTCPQTEKF
L-FHKGMEKNLEISFTQSSRKQMDNH---LSEITHPQSDGVDSTSHTDVKSDTLGHPNLD
ET-------VKAKIASRQQEELPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXX
XXXXXXXX-XXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXXXXXXX-XXXXXX
XX---XXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXKKNKSHRDIKRMQCECTPLSKDERTQGEIACGEDCLNRLLMI
EXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNGQLR
V-FFTTKLVS-GAEL-TDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSMEAETDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDFD-QLENVP---AEEEEE-----LQPQQILI
HHLPECKVDSEIAMEGSKLPTAEPEVDAEIEPKXXXXXXXXXXXXXXXXXXXXXXXXXX-
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEVYRIPKKSQAEKEST---ISERGRDAIG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPPSAYERGTKRPDDXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX---XXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X--XXXXXX-----XXXXXXXXXXXXX
XX-------XXXXXXXXXXXXXXXXXXXXX---XXXXXXXXX-XXXXXXXXX--XXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXQQQYSAQSQATIYYQGQTCPTVYG--VTSYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPTAAVTTIVAPGQPQPLQPAMVXXXXXXX
XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXQTQWDPPTWESPGDDASLEHEA
EMDLGTPTYDENPMKT--KKPKTAEADPSRELAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTEDS----------------------------------------------
-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MERRGKYSSKLERESKRTSENEAVKRC-SPPNELGFRRGS
-SYSKHDN-SS-RYKSXXXX-XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX----XXXXXXXXXXXXXX----XXXXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX--XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
----XXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XX-XX-XXXXXXXX-----XXXXXX-XXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXX-X
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX--XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XCGENTSPVLDAVLKSK-SA
EFLKHAEKETIIEVGSG--LPDSGRGFASWENRHNNGLSGKC----VQEAQEEGNSILPV
RRGRP--------ETSLDEEGGRGHAHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLEPRRHSYEEKFESI-ASKACPQTEKF
F-LHKGAEKNPEISFTQPSRKQIDNH---LSEIAHPQSDGVDSTSHSDVKSDLLG-HPNF
EGI------VKAKIASRQQEELPVYSSDDFEGVSNKSRQQTTFSNRPD-SRLGKTE-LSF
SSSCEVSRVDGFHSSEELRNLGWDFSQQEKPTTTYQQPDSSYGACGGHKYQQSTEQYSGT
RNYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EENWDQHAGSHFSSQ
ASKFFLSL-QKDKGSVQAPEISSNSIKDSLAVNEKKD-LSKNLEKNDMKDRGPLKKRRQE
LESDSESDGELQDRKKVRVEVEQG--ETAVPLGS-ALVGPSCVMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDYQFQRYG KEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSR-EDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSEPEGKDGKEDLD-QLENIP---VEDEEE-----LQSQQLLT
QQLPESKVDSEIAMEASKLASSEPEADTEIEPKE-SNGTKLDEPIAEETPSQDEEEGISD
VESERSQEQPDKTVDISDLAIKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVG
FRDQTVAPKTPNRSRERDPDKQTQS-KEKRKRRGSLSPPSSAYERGTKRPDDXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQSD-GVVHQDSSV-TVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQNYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTA EADTSSELAKKSKEVFRKE-----------------
------------------------------------------------------------
-----------------------

------------MKQLPP-Q------P-PPK---MGDFYD---P---EH-PTPEEEENEA
KIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDTPNSPAGPLQVDLTPKIKMDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLLTTATAVASPSPPV----VPLPA-VIAESTTVDSPPSSPPPP----PPPPQATI
PSPPAP-VTEPVALPHASIPVLMTA-----PVDVAARALK-EPPITTVPESSEVDTKQDA
-ISNSSEEHITQNLNEQVDTPSQKEDSHIGKEEEIPDSSK-SNLGSKKTGSKKKSSQSEG
TFLASESDEDSVRTSSSQRSHDLKFSTGIEKERDSKKSLAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERARYSRPYTDNRARESSDSEEEYKKTYSRRT------SSHS-FSYRDLRT
S-SSYSKSDRDCKTESSYLEMEKRGKYSSKLERESKRTSESEAMKRCCTPPNELGFRRGS
-SYSKHDN-SASRYKSALSK-SISKSDKFKNSFCCTELNEEIK-PSHSFNLQAPCSKGSE
LRMISKIPEREKTGSPSPSNRLNDSPTFKKLDE----SLIFKS-EFIGHDSHDSIKELDS
LSKAKNDQLRSYCPI--ELNINGSPGA-ESDLATFCTSKTDTVLMSSDDSVTGSEVSP--
----LVKA---CMLPSNGFQNISRCKEKDLDDTCMLHSKSGS-PFREAEPPVSPHQDKLM
SL----PVMTIDYS-----KTVIKE-PVDM-TVSCCKTKDSDIYCTSNDN--PSLHHSEA
E-KIEPSVMKISSNSFMN--VHLKSKTVICDNRTLTDQHSKF-ACEEYK--QSVGSTSSA
AVNHFDNLYQPIESSGIASSLQSLPPGIKVDSLTLL----QCGENTSPVLDAVLKSK-SS
EFLKLAEKETV-EVGSG--LPDSGRGFASWENRHNNGLSGKG----VQEVQEEGNSLLPD
RRGRS--------EISLDEEGGRGHAHTSDDSEVVFSSCDLNLTMEDSDG-VT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHSYEEKFESV-ASKPCSQTEKF
F-HHKGTEKNLEVSFTQPSRKQIDNH---LSEMAHPQSDGVDSTSHTDVKSDFLG-HPNS
EET------TKAKIVSRQQEELPVYSSDDFEDVPNKSRQQITFPNRPD-SRLGKTE-LSF
SSSCELSRVDGFHSSEELRNLGWEFSQQEKPTTTYQQPDSSYGACGGHKYQQSAEHYGGT
RNYWQGNGYWDPRSASRPPGTGVVYDRIQGQVPDSLTDDREE---EENWDQRGGSHFSSQ
SNKFFLSL-QKDKGSVQAPEISSNSIKDSLSMNEKKD-LSKNLEKNDMKDRGPPKKRRQE
LESDSESDGELQDRKKVRVAVEQG--ETAVPLGS-ALVGPSCVMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFDY QFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAIPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---IEEEEE-----LQSQQLLT
QQLPESKVESEITVEASKLPTTEPEADTEIEPKE-GNGTKLEETIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQTLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVAAPVEVS----SSQYVAQND-GVVHQDSSV-TVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPATAVTTIVAPGQPQPLQPPEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

------------------------------------------------------EEENEA
KIENVHKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLT
ALGNEKQNDAQNSPTAPLQADLTPKIKMDIGDTLSTTEESSPPKSRVELGKIHFKKHLLH
VTSRPLPTTLTAVASPPPPI----VPLPA-VIAESTTVDSPPLSPPPP----PPPPQTTT
SSPPAA-ITEPVALPHTPITVLMTA-PG----DVAVRALK-EPSVTVVPESSEVDTKQD-
TVSNSSEEHITQNLNEQADIPSQREDSHIGKEEEIPDSSK-SSLGSKKTVSKKKSSQSEG
TFFGSESDEDSVRTSSSQRSHDLKFSANIEKERDSKKSLAPLKSEDLG-KSSRSKTERDD
KYFSYSKLERDTRYISSRCRSERERRRSRS--RSRSDRGSRTSLSYSRSERSHYYDSDRR
YHRS-SPYRERARYSRPHTDNRARESSDSEDEYKKTYSRRT------SSHS--SYRDPRT
S-SSYSKSDRDCKTESSYLEMEKRGKYSSKLERESKRTSENEAMKRCCSPSNELGFRRGS
-SYSKHDN-SVSRYKSTPSK-SIPKSDKFKNSFCCTELNEEIK-QSHSFSLQTPCSKGSE
LRMISKIPEREKTGSPSPSNRLNDSPTFKKLDE----SPIFKS-EFIGHDSHDSNKELDS
LSKVKSDQLRSYCPI--ESNINGSPGA-ESDLATFCTSKTDTVLMSSDDSVTGSEISP--
----LVKA---CMLSSNGFQNISKCKEKDLDDTCMQHNKSES-SFRETEPPLSPDQDKLM
SL----PIMTIDYS-----KTVAKE-PVDM-RVSCCKTKDSDIYCTSNDS-NPSLCHSEA
E-NIEPSVAKISSNSFMN--VHLKSKTVIRDSRNLTDQHSKL-AYEEYK--QIVGSTSSA
SVNHFDDLYQPIESSGIASSLQSLSPGIKVDNLTLL----QCVENTPSVLDAVPKSK-TT
EFLKYAEKETIVEVDSG--LPHSGRGFASWENRHNNGLSGKC----VQEAQEEGNSILPD
RRRRP--------EISLDEEGGRGHAHTSDDSEVVFSSCDLNLTMEDSD-SVT--YTLKC
DSSGHAS-E---IVSTVHEDYSGSSESSSD-----ESDSEDTDSDDSSIPRNRLQSVVVV
PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRYSYEEKFESI-ASKACSLTEKF
F-LHKGIEKNPEISFTQPSRKQIDNH---LPEIAHPQSDGVDSTSHTDVKSDPLG-HLNS
EET------MKAKIASRQQEELPLYSSDDFEDVPNKSRQQTTFPNRPD-SRLGKTE-LSF
SSCCEISRVDGFHSSEELRNLGWDFSQQEKPTTTYQQPDSSYGACGGHKYQQSAEQYGGA
RSYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDREE---EENWDQHGGSHFSSQ
SNKFFLSL-QKDKGSVQAPEISSNSIKDSLAVSEKKD-LSKNLEKSDMKDRGPPKKRRQE
LESDSESDGELQDRKKVRMEVEQG--ETAVPPGS-ALVGPSCVMEDFRDPQRWKECAKQG
KMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMI
ECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHK
EFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR
VGFFTTKLVPSGSELTFD YQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR--AAGGKM-
KKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQ
SC-LKSFLE-RHGLSLLWIWMAELGDGRES---NQKLQEEIIKTLEHLPIPTKNMLEESK
VLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAQTPLNTPDPSTKLTTEADTDTPKKLMFR
RLKIISENSMDSAISDATSELEGKDGKEDLD-QLENVP---VEEEEE-----LQSQQLLT
QQLPESKVDSEIAMEASKLPMSETEADTEIEPKE-NNGTKLEEPIAEETPSQDEEEGVSD
VESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT---ITERGRDAVG
FRDQTAAPKTPNRSRERDPDKQTQN-KEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTS-
-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ-QQMQNLGMTSPLPYDSL--GYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP-----YDHSQPLVGHSTE
P--------LAAPPPVPVVPHVATPVEVS----SSQYVAQSD-GVVHQDSSV-AVLPVPA
PGPVQGQNYGVWDSNQQSV--SVQ-QQYSPAQSQATIYYQGQTCPTVYG-VTSPYSQTTP
PIVQSYAQPSL-QYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPAEMVVTNN-L
LDLPPPSPPKPKTIV LPPNWKTARDPEGKIYYYHVITRQTQWDP PTWESPGDDASLEHEA
EMDLGTPTYDENPMKTS-KKPKTAEADTSSE LAKKSKEVFRKEM---SQFIVQCLNPYRK
PDCKVGRITTTE--DFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQ
KFGAVYKPK--------EDTELE

Query Results

"ENSGT00780000121845_0"

ENSGT00780000121845_0