Query Results 

------------------------------------------------------------
------------------------------RYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLL

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTHLNSLDV-ELAQELGDFTEDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNQ--KNQGSSEICGFKKTGSRKDFHKTLQKQTF
ESETLEGSEPSAQTGPRCRLNVLCDVSGKGPLTACDFDLRSLPPDQRLENLLQHVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVATSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLTSFFNVSTLEREVTDVDSMVGRSTVGERRTLSQSRRL-SERALSLEENGVGS
NLKTT---PITVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEISP
APETVSCCLT--PEMLPVRPFPENRTRPHK--EILEF--PVREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASNAMPIIF-----G-KSNGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLSVHHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILVNERL
QTGSYCLPVALEKLPANYSLHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVSFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLGKDQHGRNCLLASYVHYVFRLP
ELQKDVPKSGGPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
VDEEVKNIMSSKVT-----DRNCNRMSYYCSGNNDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMST-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTDA-------------R--SGKNRSNGSDEEQEGTS
AINQNVALAIAGNNFNL-KTSGTM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QATSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYAEEDTAMQSTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAVNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTQLNSLDA-ELIQELGDFTEDDLEVVFTPKECRTVQA
SLPEEGXXXXXXXXXXXXXXXXXXXXXXX--XNQGSSDTCGFKKTGSRRDFHKTLQKQTF
ESETLDCNESSSQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-XXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDSSSQARAAIFSVTYPS
SDIYLVIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKSSVGERRTLSQSRR-LSEKSLSLEDSYIGS
SFKAT---TMTVNSFFKQEGDRLSDEDLLKFLADYKRSSSLQRRVKSIP--XXXXXXXXX
XXXXXXXXXX--XXXXXXXXXXXXXXXXXX--XXXXX--XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVIFG------KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPARLTVSHHLLFTFYHISCH---QKQGTSIESLLGYSXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXKVPPQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKVTEANLEHELKMSIICLNSSRLEPLVLFLHQILDKL
FQLSIQPMVIAGQTANFSQFAFESVVSIANSLHNSKDLSKDQHGRNCLLASYVYYVFRLP
DVQREVSKAAT-GSSH--P-DPRYHTYGRTSAAAVSSKLLQA-RVMSSSNPDIAAL-HTS
PDEEVKNIMSSKXXX---XXXXXXXXXXXX--XXXXXXXXXXXXXXXXXHFHEELALQMV
VSTGMMRESVFKYAWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLLKPQKESDQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMAP-DAAPASPNPSISSQXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXINKVQRKAISAIHGLLSSHDLDPRCSKPEVK
VKVAALYLPLVGIIMDALPQLYDFTVS-------------DVRGGKGRSNNPDEEQEGGS
PINQSVALAIAGNNFNLMKTSGAP------------------------------------
----LSSL-PYKQYNVLNSDTTRNLMICFLWIMKNADQTLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCKIP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALINGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNFARVKMQVTMSLASLVGKAS
DFNEEYLRKSLRTILAYAEEDTAMQTTPFPAQVEEL-LCNLNSILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHSKRKCYTEAAMCLVHAAALVAEYLSMLEDH
CYLPVGSVSF-----------------------QNISSNVLEESAVSDDILSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---TKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--NEQYRRNTILTTMHAFPYIKTRIRVIQKEEFVLTPIEVAIED
MKKKTLELAVAVNQEPPDAKMLQMVLQGSVGATVNQXXXXXXXXXXXXXXXXX-XXXXXX
XXXXXXXXXXXXCGEAVEKNKRLITSDQREYXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXNSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
MATLPSAER-------------RAFALKINRFSSAEIRKQFTLPPNFGQCHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

DSLDV-ELGQELGDFTDDDLDVVFTPKECRTLQP
SLPEDGVELDPHVRDCVHTYIREWLIVNQ--KNQGSSEIGGFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECAEPVAQTGPC-RLNVLCDVSGKGPFTAFDFDLRSLQPDQRLENLLQSVSSEDF
EKQNEEARRTNRQAELFALYPSVDKEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAIFSITYPS
SDIYLVVKIEKVLQQGEIADCVEPYIVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASLFSVSSLDREVTDAEPTVGRNSGGERRPLSQSRR-LSERTLSLEENGIGS
NFKTT---SMTINTFYKQEGDRLSDEDLFKFLADYKRSSSLQRRVKAIP--GLLRLEISP
APEVINGCLT--PEMLPVRPFPENRMRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEHPSNALPVIF-----G-KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTLNHHLLFTFYHISCK---QKEGASVESLLGYSWLPVLLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHALESQVTFPIRVLDQKITENVLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIASSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ERHRDASKSGGPTSL---PDPR-YHTYGRTSAAAVSSKLLQT-RVLSSSNPDLVGT-HSA
TDEEVKTIATSKAV-----DRNCSRMSYYCSGNNDAPGSTAIPRPASKKYFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNLDKSDSFRRTRFSDRFKDDITTIVNVVTS
EIGALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNIPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPVSPCPSVSSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEMK
VKVAALYLPLVGIILDALPQLYDFTDA---------------RSGKSRMNGSDEEQEGVS
AINQNVALAIAGNHFNL-KTSGTM------------------------------------
----LSSL-PYKQYSSLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKPSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDNLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDVLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQSTPFPVQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTNLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVAQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRQSFHRSSFKKCETQLSQGS-

------------------------------------------------------------
-------------MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSIST-SG
FPSLQLPQLYEPVEPVDFEGLVMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDA-ELAQELGDLTDDDLHVAFTPKECRTLQH
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEFCSFKKTGSRRDFQKSLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPDTQTGPRRPLNVLCDVSGKGPLTSCDFDLRSLQPDERLENLLQLVSAEDF
EKEKEEARKTNRPAELFALYPPVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSIDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLERESTDVEPGVGRNPVGEKRSLSQSRR-PSERTLSLEENGVGS
NFKAT---TLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISP
APDVMNCCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASGESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVSFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLP
ELHRDAPKSGGPTTVV--P-DPRYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLTGT-HCA
ADEEVKNIMSSKIAD-----RNCSRMSYYCSGNSDAPGSTAAPRPVSKKHFHEELALQMV
VSTGVVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCSQLSAKLNILPTL
ISMRLEFLRILCSHEHYLNLNLLFMNT-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLCSHDLDPRCLKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------DARSGRSRASGSYEEQDVAN
GINQNVALAIAGNHFNL-KTSGAM------------------------------------
----LSSL-PYKQYNMLNADTTRHLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRR-RIP-GTDRF
PGINENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMALASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIED
MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNKLRDSLRPMIERKIPELYKP
IFRVDSQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
-------------MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSIST-SG
FPSLQLPQLYEPVEPVDFEGLVMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDA-ELAQELGDLTDDDLHVAFTPKECRTLQH
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEFCSFKKTGSRRDFQKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPDTQTGPRRPLNVLCDVSGKGPLTSCDFDLRSLQPDERLENLLQLVSAEDF
EKEKEEARKTNRPAELFALYPPVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSIDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLERESTDVEPGVGRNSVGEKRSLSQSRR-PSERTLSLEENGVGS
SFKAT---TLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISP
APDVMNCCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFASKLASARNITIKIQFMCGEDPSNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASGESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVSFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLP
ELHRDASKSGGPTTVV--P-DPRYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLTGT-HCA
ADEEVKNIMSSKIAD-----RNCSRMSYYCSGNSDAPGSTAAPRPVSKKHFHEELALQMV
VSTGVVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCSQLSAKLNILPTL
ISMRLEFLRILCSHEHYLNLNLLFMNT-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLCSHDLDPRCLKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------DARSGRSRASGSYEEQDVAN
GINQNVALAIAGNHFNL-KTSGAM------------------------------------
----LSSL-PYKQYNMLNADTTRHLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRR-RIP-GTDRF
PGINENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMALASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIED
MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNKLRDSLRPMIERKIPELYKP
IFRVDSQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
PSAE----R-------------RAFALKINRYSSAEIRKQSTLPPNLGQHHRQSMST-SG
FPSLQLPPFYDPVEPVDFEGLLMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLEV-ELVQELGDFTDDDLDVAFTPKDCRTLQP
SLPEEGVELDPHVRDCIQTYIREWLIVNR--KNQGNSEIRGFQKSGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLESSEPADQRDPC-RLKALCDVSGKGPLTACGFDLRSLQPDQRLENLLQVVSAEDF
EKQNEEARRTNRQAELFALYPPVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQLKGFLRAHTPAVDPSSQARSAVFSVTYPS
PDIYLVVKIEKVLQQGEIADCAEPYMVIRESEGGKSKEKIEKLKLQAEAFCQRLGKYRMP
FAWAPISLANVFNLSTLEREGAEAEPVAGRSSSGERRTWSQSRR-LSERALSLEENGAGS
SFKAT---TMTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRKVKSIP--GLLKLEISP
APEVISGCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSHAMPVIFG------KSTGPEFLREVYTAITYHN
KSPDFYEEVKIKLPAKLTGSHHLLFTFYHISCQ---QKQGPSVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNFPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1712)

HL
EKFFILCHSLESQMTFPIRVLDQKISESTLEHELKLSIIWLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLAAYVYYVFRLP
ELHRDVSKSGGPTSL---SDP-RYHTYGRTSAAAVNSKLLQA-RVMSSSNPDLAGT-HCA
ADEEVKNIMSSKMS-----DRNCSRMSYYGSGNNDVPSSMAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYSWFFFELLVKSMAEYIHNLDKRDSFRRTRFSDRFQDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRVFVFNLIRQYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLSLFFMNA-DPAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLLTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIATLYLPLVGIILDALPQLYDFTDV---------------RSGKSRTNGLDDDQDVAS
SINQHVALAIAGNHFNL-KTSGTM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLLRRWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSVLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSIDVTRSQACATLYLLM

PF06920 // ENSGT00760000119234_3_Domain_2 (1712, 2267)

RFSFGASSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPIQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYEMVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFIYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTSFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQHRRNTILTTMHAFPYVKTRISVIHKEELVLTPIEVAIED
MKKKTLQLAVAIHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITPDQREYQQELRKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSLRKCESQLSQSS-

------------------------------------------------------------
------------------------------RYSSAEIRKQFTLPPNLGQYHRQSLST-SG
FPSLQLPSFYEPVEPVDFEGLLMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDAQELAQELGDFTDDDLDVVFTPKEFRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEICSFKKTGSRKDFHKTLQKQTF
ESETLECNEPTAQTGPR-HINVLCDVSGKGPLTACDFDLRSLQPDQRLENLLQHVSAEDF
EKKNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILMKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKAFLRTHTPSVATSSQARSAVFSVSYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLANFFNVSTLDREVMDVEPTVGRSSVGERRTLAQSRRL-SERALSVEENGVG-
-FKPT---TLTINTFFKQEGDRLSDEDLFKFLADFKRSSSLQRRVKSIP--GLLRLEISP
APETISCCLT--PEMSPVRPFPENRTRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVHHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
SLQRDSPKPGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGTTHST
ADEEVKNIMSSKIA-----DRNCNRMSYYCSGNNDVPTSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDPKIAGMFD
LTPEYRQQHFLTGLLFTELAAALDSEGEGISKVQKKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAA-------------DVRSGKSRPNGSDEEQEGAS
AINQNVALAIAGNQFNL-KTSGIM------------------------------------
----VSSL-PYKQYNVLNADTTRHLMICFLWVMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSHKVSTQVLQKSRDVKAKLEEALLHGEGARGEMMRR-RNP-GNDRF
PGLNENLRWKKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDNLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDMLFEEEVEQ
CADLCQRVLHHCGSSMDVTRSQACATLYLLMRFSFGATGNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPTQVKKHIPCLMHGLGSANYCIYTYIHDLYM
KIQSLQIIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHNKLQKTF
DNII---SKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKSKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKESLRPMIERKIPELYKP
IFRIESQKRDSFHRSSFRKCESQLSQGS-

------------------------------------------------------------
QREI------------------PHIQRRCLMYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDV-ELAQELGDFSEDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSDICSFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLESSEPSAQAGPR-HLNVLCDVSGKGSNTACDFDLRSLQPDPRLENLVQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVAKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDREVTDVESTVGKGSAGERRTLSQSRR-LSERAFSLEENGVGS
NSRT-----LTINNFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIAL
APETISCCLT--PEMLPVRPFPENRGRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
SLNFTNKLASARNITIKIQFMCGEDASSAMPVIFG------KSNGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGNSVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLEQKITESALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLFVQPMVIAGQPANFSQFAFESVVVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLP
EPQRDMPKSGGPTVL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGP-HCA
ADEEVKNIMSSKIA-----DRSCNRMSYYCSSNSDAPSSTTAPRPVGKKHFHEELALQMV
VSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLLKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKVAALYLPLVGIILDALPQLYDFT---------------EARGGKNRASGSDEEQEGTS
AINQNVALAIAGN-FN-LKTSGTM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLLRRWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSGMDITRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAQ
DFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEKEFVYKEPAITKLPEISHRLEAFY
SQCFGTEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRLTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTILTTLHAFPYIKTRISVAQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYGKLKENLRPMIERKIPELYKP
IFRVDSQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDA-ELAQELGDFTDDDLDVVFTPKECRTLQH
SLPEEGVELDPHVRDCVQTYVREWLIVSR--KNQGSSEVCSFKKTGSRKDFHKTLQKQTF
ESETLECSEPAAQTGPRR-LNVLCDVSGKGPLTACDFNLRSLQPDQRLENLLQLVTAEDF
EKEKEEARRANRHAELFALYPAVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPIFASIALYDIKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMVIRESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDRPVSDGEPMTGRNSVGERRSLSQSRR-LSEHA--WEENGVGY
SFKAT---TLATNSFFKQEEDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISP
APEAISCCLT--PEMQPVKPFPENRTRPHK--EILEF--PIREVYVPHTVYR--------
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PF06920 // ENSGT00760000119234_3_Domain_3 (2161, 2267)

MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYSRLKDSLRPMIERKIPELYKP
IFRIDSQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQDLGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLEQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNVMSSKMA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEVEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTGV-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
---CQKASR-------------SQRRAFAWLYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-KLAQELGDFTEDDLDVAFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNQ--KNQGSAEICSFKKTGSRRDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESESLENSEPSAQARPR-HLNVLCDVSGKGPLTACGFDLRSLQPDQRLENLLQHVSAEDF
EKQNEEARRTNRQAELFALYPAVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
VEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLTSFFNVSTLDREVTDVESMVGRSSVGERRTLSQSRR-LSERALSLEENGVGS
NFKAT---PMTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEISP
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMSGEDASNAMPIIF-----G-KSNGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVHHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
ERFFTLCHSLESQVTFPIRVLDQKISETSLEHELKLSLICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLAKDQHGRNCLLASYVHYVFRLP
EPPRDSPKSGAPTGL---PDPR-YHTFGRTSAAAVSSKLLQA-RVMSSSNPDLAGP-HCA
ADEEVKNIMSSKTA-----DRNCNRMSYYCAGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
ETAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPML
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPASPCLSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAVHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------DARSGKNRANGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGTM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQTLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMKRCRAP-GNDRF
PGLNENLRWRKEQTHWRQANEKQDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRTQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEYLRRSLRTILAYAEEDTAMQATLFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHMKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEHAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTATHDKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTILTTMHAFPYIKTRIGVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRIESPKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------RYSSAEIRKQFTLPPNLGQYHRHSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDV-ELAQELGDFTEDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYTREWLIVNR--KNQGSSEICGFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPRAQAGPR-HLNVLCDVSGKGPITACDFDLRSLQPDPRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVATSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFSVSTLDREVTDVESMVGKGSVGERRTLSQSRR-LSERALSLEENGLGS
NFKT-----MTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLKLEISL
APETINCCLT--PEMLPVRPFPENRGRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASNAMPVIFG------KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGNSVESLLGYTWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVSFPIRVLDQKISESALEHELRLSIICLNSSRLEPLVLFLHLVLDKL
FQLFVQPMVIAGQTANFSQLAFESVAVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLP
EPQRDVPKSGGPTAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HCT
ADEEVKNIMSSKIA-----DRNCNRMSYYCSGNNDAPSSTTAPRPANKKHFHEELALQMV
VSTGVVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLLTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKVAALYLPLVGIILDALPQLYDFTAA-------------DARSGKNRANGSDEEQEGSS
AINQNVALAIAGNHFN-LKTSGTM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQILLRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQTSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDITRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAQ
DFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAF
DSII---SKGQKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRLTYFEKNFNLRRF
MYT-PFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEE
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQKEYQLELKKNYHKLRESLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHLNSL

PF11878 // ENSGT00760000119234_3_Domain_0 (150, 241)

DV-PLAQDLGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLEQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNVMSSKIA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMSFFFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALKKKVEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTGV-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

----------------------------------------------------------MA
TLPSAERRA-------------F-AL-KINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYEPVEPVDFEGLLMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDV-ELAQELGDFTDDDLDVVFTPKEFRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNQ--KNQGSSEICSFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECNEPTAQAGPR-RLKVLCHVSGKGPLTACGFDLRSLQPDPRLENLLQHVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPREHLGNRILIKLLTLKFEIE
IEPLFASLALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAIFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLATFFNVSTLDREVMDVEPTVGRSSVGERRTLAQSRR-LSERALSLEENGVGS
NFRTT---TMTINTFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--VSLKLEISS
APETINCCLT--PEMLPVRPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDAGSAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDLPKSGAPPAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGTAHSA
ADEEVKSIMSSKIA-----DRNCNRMSYYCSGNNDVPSSTAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPSPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELSAALDCEGEGIGKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDSLPQLYDFTAA-------------DVRSGKSRTNGSDEEQEGVS
AINQNVALAIAGNHY--LKTSGVM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RTP-GNDRF
SGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QATSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKSKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRIAVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKESLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
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------------------------NKYWSIHTHTHTHIHTQAIKKNATTWWLPILLNERL
QTGSYCLPVALEKLPSNYFMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQVRNP
KTNS----------------------------------------ESDPAVIRAHYYWP--
GERLPQLLVSLDSSANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYAFRLP
ELHRDMHKSGGPAAT---QD-PRYHTYGCTSAATVSSKLMQA-RVMSSSNPDLAGT-HCA
ADEEVKNIMSSKVA-----DRNCSRMSYYCSGNNDAPGSTAAPRPANKKHFHEELALQMV
VSTGMVRETVFKYAWFFSELLVKSMAQYVHNLDKRDSFRKTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRSFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFLNT-DTAPVSPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDSEGDGISRVQRKAVSAIHSLLSSHDLDPRCVKSEVK
VKIATLYLPLVGIILDALPQLYDFTAA-------------DARSGKSRSSGSYEEQDVTS
GINQNVALAIAGNHFNL-KTSGSL------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQVLQKSRDVKARLEEALLRGEGARGEMMRR--RTPGNDRF
PGLNENLRWRKEQTHLWQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFRDLLFEEEVEQ
CADLCQRVLHHCSSSIDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2068)

FSFGATSNLARVKMQVTISLASLVGKAP
DFNEEHLRRSLRTVLAYSEEDTAMQTTPFPIQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNILEESAVSDDTLSPDEDRVCS
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLASTHDKLQKAF
DHII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGTEFVEVIKDSTPVDKTKLDPNKISMVLLAMNSEYNNINPQGKMCCTLEKVAQRLW
GYTTVFGLDLRPVAQEEIHVWYWS-----KDHGWGWRDGSE-------------------
VK-ST----Y-CSFRGPGFGSQKPLVEDILGVDSRRGPQE--------------------
---PWHTVI

PF06920 // ENSGT00760000119234_3_Domain_4 (2230, 2267)

IPKCGEAVEKNKRLITAEQREYQQELKKNYNKLRESLRPMIERKIPELYKP
IFRADSQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

SSLDL-ELVQELGDLKDDDLDVAFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGAPEFCSFKKTGSRKDFHKTLQKQTF
ESETLECGEPATQTGPRR-LNVLCDVSGKGPLTACDFDLRSLQPDQRLENLLQLVSTEDF
EKEKEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEITDCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLEREGVDMEPMLGRNSVSERRTLSQSRR-LSERTLSLEENGVGS
SFKPT---TLATNVFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISP
APEVINCCLT--PEMLPVRPFPENRTRPHK--EILEF--PIREVYVPHTVYR--------
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-----------------------------

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACEFDLRSLQPDKRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEVE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTFPS
SDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 836)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASNAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHT

ENSGT00760000119234_3_Linker_1_2 (836, 1713)

QLNWS
A-VRTHCHCPGETSTS---------------GS--L------------------------
RTSCGTTHFSLGSSANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
EVQRDVPKSGAPTAL---PDPRSYHTYGRTSAAAVSSKLLQA-RVISSSNPDLAGT-HSA
ADEEVKNIMSSKIA-----DRNCSRMSYYCSGNNDAPSSTAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLSNLPTL
VSMRLEFLRILCSHEHYLNLNLFFMNA-DAAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAVHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTVA-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSTQLNRILDLL
FICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVTGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMIIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINGCLT--PEMLPMKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASNAMPVIF-----G-KSNGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILL-ERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
EVQRDVPKSGAPTAI---PDPRSYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKIA-----ERNCSRMSYYCSGNSDVPGSTAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDVTTIVNVVTS
EIAALLVKAQ--------------------------------------KLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DAAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEAEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAAFYLPLVGIILDALPQLCDFTVA-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQSSDKVSTQALQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRITYFEKNFDLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRYHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELRKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
-------------MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSIST-SG
FPSLQLPQLYEPVEPVDFEGLVMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDT-ELAQELGDLTDDDLHVAFTPKECRTLQH
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEFCSFKKTGSRRDFQKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPATQTGPRRPLNVLCDVSGKGPLTSCDFDLRSLQPDERLENLLQLVSAEDF
EKEKEEARKTNRPAELFALYPPVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSIDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLERESADVEPGVGRNSVGEKRSLSQSRR-PSERTLSLEENGVGA
NFKAT---TLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISP
APDVMNCCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASGESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
ERFFTLCHSLESQVSFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIASSLHNSKDLRKDQHGRNCLLASYVHYVFRLP
ELHRDAPKSGGPTTVV--P-DPRYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLTGT-HCA
ADEEVKNIMSSKIAD-----RNCSRMSYYCSGNSDVPGSTAAPRPVSKKHFHEELALQMV
VSTGVVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCSQLSAKLNILPTL
ISMRLEFLRILCSHEHYLNLNLLFMNT-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------DARSGRSRASGSYEEQDVAN
GINQNVALAIAGNQFNL-KTSGAM------------------------------------
----LSSL-PYKQYNMLNADTTRHLMVCFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRR-RIP-GTDRF
PGINENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQ
CADLCQRVLHHCSSSMNVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMALASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTLFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGKPRGEL--HEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIED
MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNKLRDSLRPMIERKIPELYKP
IFRVDSQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------VATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEID
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTFPS
SDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASNAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMGLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
EVQRDVPKSGAPTAL---PDPRSYHTYGRTSAAAVSSKLLQA-RVISSSNPDLAGT-HSA
ADEEVKNIMSSKIA-----DRNCSRMSYYCSGNNDAPSSTAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLSNLPTL
VSMRLEFLRILCSHEHYLNLNLFFMNA-DAAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAVHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTVA-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSTQLNRILDLL
FICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
----PSAER-------------RAFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NTLDV-QLAQELGDLTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCIQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 652)

ESETLECSEPDAQTGPR-HLNVLCDVSGKGPLTACDFDLRSLQPDQRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPTVDEEDAVE--IRPVPECPKEHLGNRILVKLLMLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFLNVSTLEREVTDVDPVIGRSSAGERRTLAQSRR-LSERALSLEENGVGS
NFKTS---TLSVNSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--ANLKTLETA
----I-------NTNNSMRPWPQNAKTGHV--KINSR--QFS-LILYLFFS

PF14429 // ENSGT00760000119234_3_Domain_1 (652, 839)

RNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDAGNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVMDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKNLSKDQHGRNCLLASYVHYVFRLP
EPQRDMPKSAAPTAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSE
ADEEVKNIMSSKIA-----DRNCSRMSYYCSGNNDVPSSTTAPRPANKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSVRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFTLIRHYCNQLSAKLNNLPML
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFPELAAALDAEGEGISRVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTAM-------------R--CLRSRTSGSDEEQEGAS
AINQNVALAIAGNHFNL-KTSGIM------------------------------------
----LSSL-PYKQYNMLNADTTRSLMICFLWIMKNADQSLIRKWIADLPSVQLNRILDIL
FICVFCFEYKGKQSSDKVSTQVLQKSRDVKARLEDALLRGEGARGEMMRR-RA-PGNDRF
PGLNENLRWKKEQKVWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVRSLNCDQSTTYLTHCYATLRALIAKFGDLLFEEEVEQ
CANLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLAFLVGRAP
DFNEEHLRRSLRTILAYLEEDTAMQMTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISCNVLEESVVSDDTLSPDEDGVCI
GQYFTESGLVGLLEQASELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRTF
DSIV---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPHKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQVPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFILRCGEAVEKNKRLITPDQREYQQELKKNYNKLKENLRPMIERKIPELYKP
ILRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTHLNSLDV-ELAQELEDFTEDDLDVVFTQKECRTLQP
SLPEEGVELDPHVRDCVQTYTREWLIVNQ--KHQGSSEICGFKKTGSRKDFHKTLQKQTF
ESETLECSESSAQAGPR-HLNGLCDVSGKGPLTACDFDLRSLQPDQRLENLLQHVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLXXXXX
XXXXXXXXXXXXXXXXXXISENFHCDLNSDQFKGFLRAHTPSVATSSQAKSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKGKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFSVSTLDREVTDVESMVGRSSVGERRTLSQSRR-FSERSLSLEENGVGS
NFKTT---TMTINNFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEISL
APEIINCCLT--PELLPVRPFPENRTRPQK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASNAMPVIFG------KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDNHL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFFESVVISLHSDL-------KDQHG-------------RLP
ELQRDFLKSGGPTAL---PDP-RYHTYGRTSAAVVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKMA-------DRNRMSYYGSGNNDVPSATGAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNT-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAA-------------DARSGKNRTNGLDEEQEGTS
AINQNVALAIAGNHFS-LKTSGTM------------------------------------
----LSSL-PYRQYNMLNADTTRNLMICFLWIMKNADQSLIRRWIADLPSMQLNRILDLL
FICVSC-EYKGKPSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RVP-GNDRF
SCLSENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYAEEDKGMQTTLFPVQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDR
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX---XXGHKRMFGTYFR---VGFYGSKFGDLDEQQFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQHRRNTILTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAIHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITVDQREYQQELKKNYNKLKENLRPMMERKIPELYKP
IFRAESQKRDSFHRSSFRKCETQSSQGS-

------------------------------------------------------------
-------------MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSIST-SG
FPSLQLPQLYEPVEPVDFEGLVMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDA-ELAQELGDLTDDDLHVAFTPKECRTLQH
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEFCSFKKTGSRRDFQKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPDTQTGPRHPLNVLCDVSGKGPLTSCDFDLRSLQPDERLENLLQLVSAEDF
EKEKEEARKTNRPAELFALYPPVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSIDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNISTLERESTDVEPGVGRNSVGEKRSLSQSRR-PSERTLSLEENGVGS
NFKAT---TLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISP
APDVMNCCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFASKLASARNITIKIQFMCGEDPSNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASGESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVSFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLP
ELHRDTSKSGGPTTVV--P-DPRYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLTGS-HCA
ADEEVKNIMSSKIAD-----RNCSRMSYYCSGNSDAPGSTAAPRPVSKKHFHEELALQMV
VSTGVVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCSQLSAKLNILPTL
ISMRLEFLRILCSHEHYLNLNLLFMNT-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLCSHDLDPRCRKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------DARSGRSRASGSYEEQDVAN
GINQNVALAIAGNHFNL-KTSGAM------------------------------------
----LSSL-PYKQYNMLNADTTRHLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRR-RIP-GTDRF
PGINENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMALASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIED
MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNKLRDSLRPMIERKIPELYKP
IFRVDSQKRDSFHRSSFRKCETQLSQGS-

----------------------------------------------------------MA
TLPS-AER--------------RAFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLL

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTHLNSLDV-ELAQELGDFSEDDLDVAFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEVCSFKKIGSRKDFHKTLQKQTF
ESETLECSEPSAQAGPR-HLSVLCDVSGKGPNTACDFDLRSLQPDPRLENLVQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVASSSQARSAVFSVTYPS
SDIYLVAKIEKVLQQGEIGDCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDREVTDVESMVGKGSAGERRTLSQSRR-LSERAFSLEENGVGS
NFKT-----LTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLKLEISL
APETINCCLT--PEMLPVRPFPENRGRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASSAMPVIFG------KSNGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGNSVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISESALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLFVQPMVIAGQPANFSQFAFESVVVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLP
EPQRDMPKSGGPTVL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGP-HCA
ADEEVKSIMSSKIA-----DRSCNRMSYYCSSNSDAPSSTTAPRPVSKKHFHEELALQMV
VSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGIIKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKVAALYLPLVGIILDALPQLYDFTAA-------------EARGGKNRANGSDEEQEGTS
AINQNVALAIAGN-FN-LKTSTTM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQTLLRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAQ
DFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEKEFVYKEPAITKLPEISHRLEAFY
SQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRL

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTILTTLHAFPYIKTRISVAQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLRENLRPMIERKIPELYKP
IFRVDSQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------RHSSAEIRKQFTLQPSLGQFCQRSISG-SG
--SIQLPQFYEAVEPVDFESFL

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTQLNNLDS-ETVQELGDFPEDDLDIVFTPKECRTLQP
SLPEECVELDPHVKDCVQAYIREWLIVNR--KNQGNSETCTFKKKGSRKDFHKTLQKQTF
ESETLDSNDASYQAAPR-PLNVLCDETGRTTLTSCDFDLRSLQPDPRLENLLKHVNAEDF
ERQNEEARRANRHAELFALYPAVDEEDAVE--IRPIPDCPKEHLGNRILVKLQTLKFDIE
IEPLFACIALYDIKERKKISENFHCDLNSEQFKGFLRTHTPCIDSSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGECAEPYITLKESEGGKSKEKAEKLKVQAESFCQRLGKYRMP
FAWAPLSLANFFNVSTLEREISEAESLNGKGSTGDKKAMMLQTRRPSERSLNSEENYSTS
NFKTT---TLTISNFIKQEGDRLSDEDLFKFLTDYKRSSSLQRRVKSIP--GSLKLEISP
ASEVLNCCLT--PELLQVKPFPENRSRPQK--EILEF--PVREVYVPHTVYRNLLYVYPQ
RLNFANRLGSSRNITIKIQFMCGEDATCAMPIIFG------KSSGPEFVQEMYTAITYHN
KSPDFYEEVKIKLPAKLTGKHHLLFTFYHISCQ---PKQGVCAETLLGYSWLPILLNDRL
QTGHYCLPVAVDKLPLNYSMHSPEKVPSQTPPIKWVEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVMDQKITEGTLEHELKLSIICLNSSRLEPLVLFLHLVLEKL
FQLAVQPMVIAGQTANFSQFAFESVVAIVNSLHNSKDLSKDQHGRNCLLASYIYYVFRLP
EPQQDIARLGAAGSANLP--ESRYYTCGRTSAVSVGSKLLQS-RVMSCSNPDIAGV-QTA
TDEEVKNIMSSKVA-----DRGSSRMSFYIEPNNDTSNTCASPRPTNKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLIKSMAQHVNNVDKQDSPRRSRFSDRFKDDITTIVNVVTS
EIAALLVKVQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSSKLNTLPTL
ISMRLEFLRILCSHEYYLNLNLFFMTS-VSAPASPSPSLSSQNSSSCSSFQDQKIASMFD
LSAEYRQQHFLTGLLFTELAAALDTEAEGISKVQRKAISAVHSLLSSHDLDQRCLKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------EARSGKGRAGTPDEDQESAN
PINQSVAWAIAGNQFSLLRTSNAP------------------------------------
----LSSL-PYKQYNTLSPDTTRNLLICFLWIMKNAEQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMKRCRTPAGNDRF
PGLNENLRWRKEQTQWRQANERLDKTKADLDQEALISGNLATEANLIILDMQENII----
--QASSAADCKDNLLGSVLKVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQ
CADLCQRVLHHCSSSIDITRTQACATLYLLMRHSYSSISNFSRVKMQVTMSLASLVGKSS
DFNEEYLRRSLRTILAYAEEDVDMQPTQFPIQVKEL-LRNLNNILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHAKKKCYTEAAMCLVHAAALVAEYLSMLEDH
KYLPVGSVSF-----------------------QNISSNVLEESAVSDDILSPDEDGICS
GRYFSESGLVGLLEQAAELFSTGGLYETVNEVYKIVIPILEAHRDFRKLTSTHSKLQKAF
DSII---NKGQKRMFGTYFR---VGFYGSKFGDLDELEFVYKEPAITKLPEISHRLEGFY
GQCFGEDAVQVIKDSAPVDRGKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLDGRPRGDL--SEQYKRNTILTTMHAFPYVKTRIGVIQKEEYTLTPIEVAIED
MQKKTLELAVATNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQLELKKNYNKLKENLRPMIERKIPELYKP
IVKVRSTTRDSFRNSSFKKHEAHSSQNI-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

DSLDA-ELAQELGDLTDDDLHVAFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEFCSFKKTGSRRDFHKTLQKQTF
ESETLECSEPATQTGPCR-LKVLCDVSGKGPLTTCDFDLRSLQPDERLENLLQLLSAEDF
EKEKEEARKTNRPAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMVIKESDGGKVWS--------SKYSCLHSRKYHLL
IDWCPFKNLFLLM---------TVVFLKGRNSVGERRSLSQSRR-PSERSLSFEENGVGS
NFKTT---TLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISP
APDVMSCCLT--PEMLPVKPFPENRTRPHK--EVLEF--PIREVYVPHTVYR--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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-----------------------------

------------------------------------------------------------
------------------------------RYSSAEIRKQFTLQPGFAQFCQRSLST-PG
FSTLHLPSFYDAVDPLDFEGFLMMQLNNLDS-ELAHELGDFPEDDLDVVFTPKECRTLQP
SMPEDGVELDSHVRDCVQTYIRDWLIVNR--KNQGNSDTCNLKNKGSRKDFHKRLQKQTF
ESETLDSGEATFQTGPR-HVPTLPEDTSRTAPASCDFDLRSLQPDPRLENLL-HVSAEEF
ERQNEEARRTNRHAELLALYPSVDEEDAVE--IRPVPDRPKEHLGNRILVKLQSLKFDIE
IEPLFACIALYDIKERKKISENFHCDLNPDSLRGFLRSHTPSIDLSTQARSAVFSVTYPS
SDIYLVIKIEKVLQQGEIGDCAEPYMVLKESEAGKTKEKIEKLKAQAESFCQRLGKYRMP
FAWIPISLTNFFNVSTLEREIPETEGLNGSHT-SDKKATLLQARRLSERSLSSEDNYPAS
NFKTI---SLTLSTFFKQEGDRLSDEDLFKFLADFKRSSSLQRRIKTLP--GTLKLEISP
APENLGYCLT--PELLPVKPFPENRSRPHK--EILEF--PIREVYVPHTIYRNLLYVYPQ
RLNFANRPASARNITIKIQFMCGEDPSCAMPVIFG------KSSGPEFVQEIYTAITYHN
KSPDFYEEVKIKLPAKLTEKHHLLFTFYHISCQ---PKQGASVETVVGYSWLPILLNDRL
QTGHYCLPVALDKLPFHYSIHSPEKVPSQTPPIKWVEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRLMDQKITEATLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLAVQPMVIAGQTANFSQFAFESVVAIVNSLHNSKDLSKDQHGRNCLLASYVYYVFRLP
DPQREVAKPGAGGSAVLS--ESRYYTFGRASAVTVGSKLLQS-RVISCSNPDITVT-QAA
TDEEVKSIMSSKPV-----DHSSSRMSFYIEGTNDTPNVCANPRPSNKKHFHEELALQMV
VSTGMVREAVFKYAWFFFELLIKSMAQYVHNIEKQDNPRRSRFSDRFKDDITTIVSVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSNKLNSLSTL
ISMRLEFLRILCSHEHYLNLNLFFMTS-ASAPASPSPSLSSQNSSSCSSFQDQKIAGMFD
LSSEYRQQHFLTGLLFTELSAALDADSEGISKVQKKAVSAILSLLSSHDLDPRCSKKEVK
IKIAALYLPLVGIILDSLPQLHDFT---------------NARSGKGRTGNPEEEQDSAG
AINQNVALAIAGNQFSL-RSSGIS------------------------------------
----LASL-PYRQSATLGPDTTRNLLICFLWIMKNADQNLIQKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQALQKSRDVKARLEEALLRGEGARGEMMKRCRIP-GNDRS
AGLNENLRWRKEQTHWRQANERQDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASFAAECRDNLLGGVLKVLVNSLGCDQSTTYLTHCFATLRALIAKFGDFLFEEEVEQ
CADLCQRVLHHCSSSIDVTRTQACATLYLLMRYSFSSTSNFARVKMQVTMSLASLVGKSP
EFNEEFLRRSLRTILAYAEEDVDMQATPFPLQVEEL-LCNLNSILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDVLSPDEDGICS
GRYFSESGLVGLLEQAAELFSTGGLYETVNEVYKIVIPILEAHRDFRKLTLTHSKLQKAF
DSII---NKGQKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGEDAVEVIKDSAPVDKSKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLCRF
MYTTPFTMDGRPRGEL--SEQYKRNTILTTMHAFPYIKTRINIIQKEEFILTPIEVAIED
MRKKTQELTAATNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVDKNKRLITADQREYQQELKKNYGKLKENLRPMIERKIPELYNA
VVKVHSTSRESFHNHSFKKYDAQSSQST-

----------------------------------------------------------MA
TLPSAERRA-------------FA--LKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FHSLQLPQFYDPVEPVDFEGLLMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDV-ELAQELGDFTDDDLDVTFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYTREWLIVNR--KNQGSSEIFSFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLENSEPATQTGPR-RVNVLCDVSGKGPLTACDFDLRSLQPDQRLENLLQYVSSEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRIL-----------
------------------ISENFHCDLNSDQFRGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKVEKVLQQGEIADCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMP
FAWAPVNLASIFNVSTLDREVTDVEPTVGRSSAGDRRNLSQSRR-LSERALSLEENGVGS
NFKTT---PMTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLKLEISP
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 836)

HTMYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSHAMPVKRG------PH------------LQINI
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHT

ENSGT00760000119234_3_Linker_1_2 (836, 1713)

QVRNT
KANFESDPAV----------------------------VRTHGCW--------------L
EEHSLQVHVSLGSSANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELHRDSPKQGSVEV----------------------------------------------
-----KNIMSSKVGKMANPVSFNVRMSYYCSGNNDVPGSTAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTWFSDRFKDDITTIVNVVTS
EIAALLVKPPKSEEERY------YYFC---YPQLHLNFF--FLFIFPFQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEIK
VKIAALYLPLVGIILDALPQLYDFTAV----------------SGKSRTSGSDEEQDGPS
AINQNVALAIAGNHFN-LKTSGTM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RTP-GNDRF
PGLNENLRWKKEQTHWRQANEKSDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDTTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRKSLRTILAYSEEDTDMQTTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPMEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRAESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----GGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEICGFKKTGSRKDFHKTLQKQMF
ESETLECSEPSSQAGPC-HLNVLCDVSGKGPITACDFDLRSLQPDLRLKNLVQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPDCPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVATSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDREVTDVESTVXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXX---XXXXXXXXXXEGDRLSDEDLFKFLADYKRSSSLQRRVKSVP--GLLKLEISL
APEMTSCCLT--PEMLPVRPFPENRGRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASNAMPVIFG------RSNGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGNSVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISEAALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLFVQPMVIAGQTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXSPTSF---PDP-RYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLVGT-HSA
ADEEVKNIMSSKMT-----DRSCIRMSYYCSGNNDAPSSTTTPRPVSKKHFHEELALQMV
VSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQREIEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPML
ISMRLEFLRILCSHEHYLNLNLFFMNT-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLAGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKVAALYLPLVGIILDALPQLCDFTAA-------------DARSGKNRTNGSDEEQEGTS
AINQNVALAIAGN-FT-LKTSGTM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLLRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDNLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVDQ
CADLCQRVLHHCGSSMDVARSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEYLRRSLRTILAYAEEDTDMQTTPFPMQQ-EL-LCNLNS-IYDTVKMREFQD--EM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKGKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSRFGDLDEKEFVYKEPAITKLPEISHRLEGFY
SQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRL

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFDLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAVNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQMELKKNYNKLRENLRPMIERKIPELYKP
IFRVDSHKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDE-ELAQELGDFTADDLDVVLTPKECRTLQP
SLPEAGVDLDPHVKDCVHTYTREWLIVNR--KNQGSSEIYGFKKTGSRKDFHKTLQKQTF
ESET-ERAEPAAQRGPC-RLKVLCDVSEKGPFTAFDFDLRSLQPDQRLENLLRSVSSEDF
EKRNEEARRTNRQAELFALYPSVDKEDAVE--IRPVPECPKEHLGNRILVKLQTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSIDLSSQARSAIFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYIVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLDKEVTDAEPTFGRNSGGERRSLSQSRR-LSERTLSLEENGIGP
NFKTTMTLDFS---FSWQEGDRLSDEDLFKFLADYKRSSSLQRRVKAIP--GLLRLEISP
ALELINGCLT--PEMLPVVPFPENRTRPHK--EILEF--PIREVYVPHTVYR--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-----------------------------

------------------------------------------------------------
-------------MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQCHRQSIST-SG
FPSLQLPQLYEPVEPVDFEGLVMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDA-ELAQELGDLTDDDLHVAFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSDFCSFKKTGSRRDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPATQTGPRR-LNVLCDVSGKGPLTTCDFDLRSLQPDERLENLLQL-SADDF
EKEKEEARKTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLERESTDVEPVAGRNSAGERRSLSQTRR-SSERSLSLEENGVGS
NFKGT---TLAINTFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEVSP
APDVMNCCLT--PEMLPVKPFPENRTRPHK--EVLEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSNAMPVIFG------KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASGESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLP
ELHRDTPKSGGPA-AT--P-DPRYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLAGA-HCA
ADEEVKNIMSSKIAD-----RSCSRMSYYCSGNNDVPGSTAAPRPVSKKHFHEELALQMV
VSTGIVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNTLPTL
ISMRLEFLRILCSHEHYLNLNLLFMNT-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------DARSGKSRASGSYEEQDVAN
GINQNVALAIAGNHFNL-KTSGAM------------------------------------
----LSSL-PYKQYNMLNADTTRHLMVCFLWIMKNADQGLIRRWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKAKLEEALLRGEGARGEMMRR-RTP-GNDRF
PGLSENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMALASLVGKAP
DFNEEHLRKSLRTILAYSEEDTAMQTTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRIRVIQKEEFVLTPIEVAIED
MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNKLRDSLRPMIERKIPELYKP
IFRIDSQKRDSFHRSSFRKCENQLSQGS-

------------------------------------------------------------
------------------------------RYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLL

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTQLNSLDA-ELAQELGDFTEDDLDVAFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNQ--KNQGSPEIGSFKKSGSRRDFHKTLQKQTF
ESESLEGREPSTQARPR-PLNVLCDVTGKGPLTACGFDLRSLPPDPRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAYTPSVAPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKEGDGGKSKEKIEKLKLQAEAFCQRLGKYRMP
FAWAPISLTSFFNVSTLDREVTDVESMVGRGSAGERRTLSQTRR-LSERALSLEENGVGS
NYKTT---TMTVNSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKPIP--GLLRLEISP
APEIISGSLT--PEMLPVKSFPENRTRPHK--EILEF--PIREVYVPHTVYRKIFYIYLQ
RLNFANKLASARNITIKIQFMCGEDASNAMPVNTCLGLWGYSSMGPRVLKAFSCTMYFRN
RSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPSQTPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLENQVTFPIRVLDQKISEMALEHELKLSLICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSNDLAKDQHGRNCLLASYVHYVFRLP
EPPRDPPKSGVYAPYEIVPTP-AFLTYRINAPSTTSYTRFATMGCCSTHETTNRDCCFTF
VTKKKKKQPKKKNS-----DRSCNRMSYYCSANNEVPGSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
ETAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLTNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNV-DAAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAA-------------DARSGKSRANGSDEDQEGTS
AINQNVALAIAGNNFNS-KTSGTI------------------------------------
----LSSL-PYKQYNVLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLNENLRWRKEQTHWRQANEKQDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEYLRRSLRTILAYAEEDTAMQATPFPTQQVEELLCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEHAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DCII---SKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGEEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTGHAFPYVKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPRLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYHKLKENLRPMIERKIPELYKP
IFRVESHKRDSFHRSSFRKCETQSSQGS-

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQDLGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPTAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLEQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNVVSSKIA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEVEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFT---------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLAGRPRGEL--HEQHRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

----------------------------------------------------------MA
TLPTAERRA-------------FA--LKINRYSSAEIRKQFTLPPNLGQVYQRSVSI-SG
FPSLQLPQFYDPVEPGDFEGLL

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MSQLSSLDA-ELVQELGDFPEDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSETCGFKKTGSRRDFHKMLQKQTF
ESETLDCNESSSQAGPR-TLKVLCDVSGRSTLTSCDFDLRSLQPDPRLDSLLQQVSAEDF
ERQNEEARRTNRQAELFALYPSVDEEDAVE--IRPLPECPKEHLGNRILVKLQTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPVVDPSSQARAAIFSITYPS
SDIYLVIKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKVEKLKIQAESFCQRLGKYRMP
FAWAPISLTSFLNVSTLDREIADMETMVGKGSVGERRTLSQSRR-LSEKSLNLEDNYIGS
NFKTT---TMTVNSFFKQEGDRLSDEDLLKFLADYKRSSSLQRRVKSIPGMGGTPL--LS
AKKVFPPCLL--TEMIRVKTIRENRTRPHK--EILEF--PIKEVYVPHTVYRNLLYVYPQ
RLNFANRMASARNITIKTQFMCGEDANSAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCH---QKQGTSVESILGYSWLPILFNERL
QTGPYCLPVALEKLPANYSMHSPEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDHKITEANLEHELKLSIICLNSSRLEPLVLFLHQILDKL
FQLSVQPMVIAGQTANFSQFAFESVVSIANSLHNSKDLSKDQHGRNCLLASYVYYVFRLP
DVQREVSKSAGGSSH---PDP-RYHTYGRTSAAAVNSKLLQA-RVMSSSNPDIAGM-HTS
PDEEVKHIMASKVA-----DRVSNRMSYYSQGNNDTPNSTTVPRPASKKHFHEELALQMV
VSTGMVRESVFKYAWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENDQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMAP-DNAPASPNPSISSQNSSSCSSFQDQKIASMFD
LTPDYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAISAIHGLLSSHDLDPRCSKPDVK
VKVAALYLPLIGIIMDALPQLYDFTVS-------------DVRGGKGRPNSSDEEQEGGS
PINQSVALAIAGNQFNPLKMSGVT------------------------------------
----LSHLPPYKQYNVLNPDTTRNLMICFLWIMKNAEQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCKTPAGNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALINGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSILITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAS
DFNEEYLRKSLRTILAYAEEDTAMQATPFPAQVDEL-LCNLNSILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHSKKTCYTEAAMCLVHAAALVAEYLSMLEDR
CYLPVGSVSF-----------------------QNISSNVLEESAVSDDILSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKGHKRMFGTYFR---VGFYGSKFGDLDEMEFVYKEPAITKLPEISHRLEGFY
GQCFGANFVEVIKDSTPVDKTKLDPQKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--SEQYRRNTILTTMHAFPYIKTRIKVIQKEEIVLTPIEVAIED
MKKKTLELAVAVNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITSDQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRIQSEKRNSFHRSSFRKCETQLSQGT-

--------------------------------------------------------IARL
--------------------------PSSKMYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQDLGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLEQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDMPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNVMSSKMA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSTKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEVEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFT---------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKVAGG--ETYFRKTPLEVRGPTFGDLDEQEFVYKEP-------------AFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------RYSSAEIRKQFTLPPNLGQYHRHSINT-SG
FPSLQLXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXVELDPHVRDCVQTYTREWLIVNQ--KNQGSSEVCGFKKTGSRKDFHKTLQKQTF
ESEILECSEPSAQAGPR-HVSVLCDVSGKGPLTACGFDLRSLKPDQRLENLLQRVSSEDF
EKQNEEARRTNRPAELFALYPSVDEXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTFPS
PDIYLVIKIEKVLQQGEIGDCAEPYMVIKEGDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLEREAADAESTFGRNSAGDRRPLSQTRK-LCERALSLEENGLSS
SYKTT---TMTLNSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISL
APDTLSCCLT--PEMLPVRPFPENRARPHK--EILEF--PIREVYVPHTVYXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDNHL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLAVQPMVIAGQTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXGPTAS---PDP-RYHTYGRTTAAAVSSKLLQA-RVMSSSNPDLVAT-HSA
ADEEVKSIMSSK-A-----DRNCNRMSYYSSGNNEVPSSSAVPRV-SKKHFHEELALQMV
VSTGMVRETVFKYAWFFELLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX-XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXA-------------DTRGGKNRASGSEEEQEGSS
AINQNVALAIAGNHFN-LKTGGLT------------------------------------
----LSSL-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDAKARLEEALLRGEGARGEMMRR-RIV-ANDRF
QGLNENLRWKKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLQHCSSSMDVTRGQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYAEEDTAMQPTPFPVQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIADSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXGGLYETVNEVYKLVIPILEAHRC-GKLTSTHDKLQR-V
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNSVLTTMHAFPYIKTRIRVVQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQSSS

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PF06920 // ENSGT00760000119234_3_Domain_3 (2161, 2267)

MKKKTLQLAVAVHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITAEQREYQTELKKNYNKLRESLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASNAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
EVQRDVPKSGAPTAL---LDPRSYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKIA-----DRNCSRMSYYCSGSSDAPSSPAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCSQLSAKLSNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTVA-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSTQLNRILDLL
FICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSEDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
-------------MATLPAADRRAFALKINRHSSAEIRKQFTLQPGFAQFCQRSLST-PG
FSTSNLPSFYDAVDPVDFEGFLM

PF11878 // ENSGT00760000119234_3_Domain_0 (144, 241)

TQLNNLDL-DLAQELGDFPEDDLDVVFTPKEFRTLQP
SVPEDGVELDSHVKDCVQTYIREWLIVNR--KNQGSSDTCSLKNKGSRKDFHKTLQKQTF
ESETLDSGDATFQAGPQ-HMPALPEEASRPSLGCSDLELRSLQPDPRLEQLLRHVSAEEF
ERLNEEARRTNRHPELLALYPSVDEEDAVE--IRPVPDCPKEHLGNRILVKLQTLKFDIE
IEPLFASIALYDIKERKKISENFHCDLNSDSLRGFLRSHTPSIDLSTQARSAIFSVTYPS
PDIYLVIKIEKVLQQGEIGDCAEPYMVLKESDAGKTKEKIEKLKAQAESFCQRLGKYRMP
FAWIPISLSNFFNISTLEREIQEAEGLNGTYSSSDKKATLLQARRLSERSFNSDDPAST-
---------KTLNTFFKQEGDRLSDEDLFKFLADFKRSSSLQRRIKTLP--GTLKVEISP
APENIGYCLT--PELLPVKPFSENRNRPLK--EILEF--PIREVYVPHTIYRNLLYVYPQ
RLNFANRLASARNITIKIQFMCGEDPSCAMPVIFG------KSSGPEFVQEIYTAITYHN
KSPDFYEEVKIKLPAKLTEKHHLLFTFYHISCQ---PKQGASVETLLGYSWLPILLNDRL
QTGHYSLPVALDKLPLHYSIHSPEKIPSQTPPIKWVEGHKGVFIVDVQVVSSVHTQDNHL
EKFFTLCHSLESQVTFPFRVMDQKITEASLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLAVQPMVIAGQTANFSQFAFESVVAIVNSLHNSKELSKDQHGRNCLLASYVYYVFRLP
DPQREVVKPGGGSSAVST--ESRYYTFGRTSAVSVGNKLLQS-RVISCSNPDITVA-QAT
ADEEVKSVMSSKPV-----DHSSSRMSYYTEGTNDMSGLCASTRPSNKKHFHEELALQMV
VSTGIVRETVFKYAWFFFELLIKSMAQYVHNTEKQDNPRRSRFSDRFKDDITTIVGVITS
EIAALVVKPPKESEQAENINISLAFFLYDLLSLMDRGFVFKLIKHYCNQLSNKLNSLSTL
ISMRLEFLRILCSHEHYLSLNLFFMTS-ASAPASPSPSLSSQNSSSCSSYQDQKITGMFD
LSTEYRQQHFLTGLLFTELAAALDADSEGISKVQRKAVSAILSLLSSHDLDPRCSKKEVK
IKIAALYLPLVGIILDSLPQLHDFT---------------NIRSGKGRTGNPEEEQESSS
AINQNVALAIAGSQFNI-RNSGIP------------------------------------
----LVSL-PYRQSATLGPDTTRNLLICFLWIMKNADQNIIQKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQALQKSRDVKARLEEALLRGEGARGEMMKRCRIPAGNDRS
AGINENLRWRKEQTQWRQANERQDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASFAAECRDNLLGGVLKVLVNSLGYDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSIDITRTQACATLYLLMRYSFSSTSNFSRVKMQVTMSLASLVGKSP
EFNEEFLRRSLRTILAYAEEDADMQATPFPIQVEEL-LCNLNGILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVSEYLSMLEDR
NYLPVGSISF-----------------------QNISSNVLEESAVSDDVLSPDEDGICS
GRYFSESGLVGLLEQAAELFSTGGLYETVNEVYKIVIPILEAHRDFRKLTLTHSKLQKAF
DSII---NKGQKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGEDVVEVIKDSAPVDKRKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNICRF
MYTTPFTVDGRPRGEL--HEQYKRNTILTTMHAFPYIKTRLNVIQREEFILTPIEVAIED
MRKKTQELTAATNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKHLITADQREYHQELKRNYIKLKDSLRPMIERKIPELYKP
V----------------------------

--------------------------------------------------------FVFG
TGIE------------------PRAFVLSFISKFPEIRKQFTLPPNFGQCHRQSIST-SG
FPSVQLPQFYDPVEPVDFEGLLMTQL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NNLDV-ELAQELGDFTDDDLDVVFTPKECRTLQP
SLPEDGVDLDPHVRDCVHTYIREWLVVNR--KNQGSSENCGFKKTGLRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETVESVEPAAQTEPR-RLNVLCDVSGKGPFTAFDFDLRSLQPDQRLENLLQSVSSEEF
EKQNEEARRTNRQAELFALYPSVDKEDAVE--IRPVPECPKEHLGNRILVKFLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQLKGFLRAHTPSVDLSSQARSAIFSVTYPS
PDIYLVVKIEKVLQQGEITDCAEPYIVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDKEVTDVEPTIGRNSGTERRSLSQSRRL-SERALSLEENGLGS
NFKTT---SMTINSFYKQEGDRLSDEDLFKFLADYKRSSSLQRRVKAIP--GVLRLEVSP
APEVISGCLT--PEMLPVIPVPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 837)

HTVYRNLLYVYPQ
RLNFANKLTSARNITIKIQFMCGEDPSNALPVIF-----G-KSSGPEFVQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---PKQGASVESLLGYSWLPIVLNERL
QTGSYCLPVALEKLPPNYFMHSAEKVPLQNPPIKWVEGHKGVFNIEVQAVSSVHAQ

ENSGT00760000119234_3_Linker_1_2 (837, 1713)

DIHL
EKFFTLCNSLESQVTFPVRVLDQKITENILEHELKLNIIHLNSSRLEPLVLFLHLVLDKL
FQLSVQSMFIAGQPANFSQFAFESVATIATSLHNSKDLSKDQHGRNCLLASYVHYAFRLP
EPHRDAPKSGGPPSL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLSGS-HSA
ADEEVKNIMSSKAV-----DRTCNRISYYCSGNNDVPGSSAAPRPASKKHFHEELALQMV
VSTGMVRESVFKYSWFFFELLVKSMAQYVHNLDKSDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLSNIPTL
ISMRLEFLRILCSHEHYLNLNLFFMNT-DTAPASPCPSISSQNSSSCSSFQDPKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTDA-------------R--GGKSRTNGSDEEPEGLS
AINQNVAQAIAGNHLNL-KTSGTM------------------------------------
----LSSL-PYKQYNTLNADTTRNLMICFLWIMKNADQSLIKKWIADLPSMQLNGILDLL
FICVSCFEYKGKPSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
QGLNENLRWRKEQTHWRQTNEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QVRTINTCFELILY------------------L------KFLLFVIFGDLLFEEEVEQ
CADLCQRVLHHCSSSIDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQSTPFPVQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLASTHDKLQKAF
DHII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKHSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--QEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKESLRPMIERKIPELYKP
IFRVESQKRESFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------LIF-------------LRGFAMLARYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDI------SENFHCDLNSDQFKGFLRAHTPSVDASSLARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGLGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDACSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKIA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFT---------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNHFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALITKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTRLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRIESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
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------------------------------M

PF06920 // ENSGT00760000119234_3_Domain_3 (2132, 2267)

HAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAVNQEPPDAKMLQMVLQGCVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESEKRESFHRSSFRKCDSQLSQGS-

----------------------------------------------------------MA
TLPSAERRA-------------F-AL-KINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NTLDV-ELAQELEDFTDDDLDVVFTPKECRTLQA
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGISEICGFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLEGNEPTSQTGPR-HLNVLCDVSGKGLLTACDFDLRSLQPDQRLENLLQHVNAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVATSSQARSAIFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDGGKSKEKIEKLKFQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLDREVTDVEPMVGRSSVGERRTLAQSRR-LSERALSLEENGAGS
NFKTT---TMTINSFFKQEGDRLSDEDLFKFLADFKRSSSLQRRVKSIP--GLLRLEISS
APEIINCCLT--PEMLPVRPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDTSNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGPSVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDMPKPGAPAAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKVT-----DRNCNRMSYYCSGNNDVPSSTAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSFRRTRFSDRFSDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLFSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNT-DTAPVSPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAA-------------DARSGKSRTNGSDEEQEGTS
AINQNVALAIAGNHFN-LKTSGIM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDITRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDIAMQTTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---SKDHKRMFGTYFR---VGFYGSKFRDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFILRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MVIKESDGGKSKEKVEKLKVQAESFCQRLGKYRMP
FAWAPISLTNFFNISTLEREVTDMETMVGRSSVGERRSLSQSRR-LSERALSLEENGVGS
NFKTT---PVTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLKLEISP
APETLNCSLT--PEMLPVRPFPENRTRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDVSNAMPVIFG------KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPVQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISEAALEHELKLSIIWLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLTKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGGPPPL---PDP-RYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLAGT-HSA
ADEEVKSVLSSKIA-----DRSCNRMSYYSSGNNDVPGSTATPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSIRRTRFSDRFQDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTSPASPSPSISSQNSSSCSSFQDHKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKSEVK
VKVAALYLPLVGIILDALPQLYDFTAA-------------DARSGKNRANGSDEEQDGTS
AINQNVALAIAGNHFN-LKTSGMM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLNENLRWRKEQTHWRQATEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRKSLRTILAYAEEDTAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
CYLPVGSVSF-----------------------QNISSNVLEESAVSDDIVSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVTPILEAHRDFRKLTSTHSKLQKAF
DSII---NKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--QEQYRRNTVLTTMHAFPYIKTRISVVQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKHLITADQREYQQELKKNYNKLKENLRPMMERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
-------------MATLPAADRRAFALKINRHSSAEIRKQFTLQPGFAQFCQRSLST-PG
FSTCNLPSFYDAVDPVDFEAFLM

PF11878 // ENSGT00760000119234_3_Domain_0 (144, 241)

TQLNNLDL-DLAQELGDFPEDDLDVVFTPKECRTLQP
SMPEDGVELDSHVKDCVQTYIREWLIVNR--KNQENSDICSLKNKGCRKDFHKTLQKQTF
ESETLDSGDGTFQAGPQ-QVPAVE-EASRATLACSDLELRSLQPDPRLEHLLRHVSAEEF
ERLSEEARRTNRHPELLALYPSVDEEDAVE--IRPVPDRPKEHLGNRILVKLQTLKFDIE
IEPLFACIALYDIKERKKISENFHCDLNSESLRGFLRSHTPSIDLSTQARSAVFSVTYPS
PDIYLVIKIEKVLQQGEIGDCAEPYMVLKEGEAGKTKEKIEKLKAQAESFCQRLGKYRMP
FAWIPISLTNFFNVSTLEREIQEAEGLNGKGSSSDKKATLLQARKLSDRSFNSEDSYPTS
NFKPT---SLSLGTFFKQEGDRLSDEDLYKFLADFKRSSSLQRRIKTLP--GTLKVEISP
APENIGYCLT--PELLPLKPFSENRNRPHK--EILEF--PIREVYVPHTIYRNLLYVYPQ
RLNFANRLSSGRNITIKIQFMCGEDPSCAMPVIFG------KSSGPEFVQEIYTAITYHN
KSPDFYEEVKIKLPAKLTEKHHLLFTFYHISCQ---PKQGASVETLLGYSWLPILLNDRL
QTGHYSLPVALDKLPLHYSIHSPEKIPSQTPPIKWVEGHKGVFIVEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRMMDQKITEASLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLAVQPMVIAGQTANFSQFAFESVVAIVNSLHNSKELSKDQHGRNCLLASYVYYVFRLP
DPQKEVVKPGGGSSAIST--ESRYYTFGRTSAVSVGSKLLQS-RVISCSNPDITVT-QAA
ADEEVKSIMSSKPM-----DHSSSRMSYYAEGTNDVSGLCASTRPSNKKHFHEELALQMV
VSTGMVRESVFKYAWFFFELLIKSMAQYVHNTEKQDNPRRSRFSDRFKDDITTIVSVITS
EIAALVVKPPKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSNKLNSLSTL
ISMRLEFLRILCSHEHYLNLNLFFMTS-ASAPASPSPSLSSQNSSSCSSFQDHKITGMFD
LSAEYRQQHFLTGLLFTELAAALDADIEGISKVQRKAVSAILSLLSSHDLDPRCSKKEVK
IKIAALYLPLVGIILDSLPQLHDFTVS-------------DVRSGKGRTGNPEEE-ESSG
AINQNVALAIAGSQFSV-RNSGIP------------------------------------
----LVSL-PYRQSATLGPDTTRNLLICFLWIMKNADQNLIQKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQALQKSRDVKARLEEALLRGEGARGEMMKRCRIPAGNDRS
AGVNENLRWRKEQTQWRQANERQDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASFAVECRDNLLGGVLKVLVNSLGYDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSIDITRTQACATLYLLMRYSFSSTSNFSRVKMQVTMSLASLVGKSP
EFNEEFLRRSLRTILAYAEEDIDMQATPFPIQVEEL-LCNLNSILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDR
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDVLSPDEDGICS
GRYFSESGLVGLLEQAAELFSTGGLYETVNEVYKIVIPILEAHRDFRKLTLTHSKLQKAF
DSII---NKGQKRMFGTYFR---VGFYGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGEDAVEVIKDSAPVDKSKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNICRF
MYTTPFTMDGRPRGDL--SEQYKRNTILTTMHAFPYIKTRINVIQREEFILTPIEVAIED
MRKKTQELTAATNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAAIPEDPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRHLITADQREYHQELKRNYMKLKENLRPMIERKIPELYKP
VVKVHSISRESFRNHSFRKYDAQTSSQS-

------------------------------------------------------------
------------------------------RYYSAEIRKQLTLPPNLGQYHRHSISS-SG
FPALQLPQFYDPVEPVDFEGLLMTHLNRLDV-ELTQELGDFSEDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNQ--KNQGSSEVCSFKKTGSRKDFHKTLQKQNF
ESETLESSERRTQAGPW-HVNILCDVSGKGPLTACDFDL-SLQPDPRLENLLQQVSAEDF
EKQNEEARRTNRQAEIFALYPPVDEEDAVE--IRPVPECPKEHLGSRILVKVLTLKFEIE
IEPLFASLALYDVKERKKISENFHCDLNSDQFRGFLRAHTPSVATSSQARSALFSVTYPS
SDIYLVIKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGRYRMP
FAWAPISLTSFFSVSTLEREVTEVESMTXXXXXXXXXXXXXXXXXXXXXXX----XXXXX
XXXXXXXXXXXXXXXXXXEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEVLSCCLT--PEMLPVNPFPENRTRPHK--EILEF--PIREVYLPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSNAMPVIFG------KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGTSVESLVGYSWLPVLLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPVQSPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXGPP---ALPD-PRYHTYGRTAAAAVSSLMHA--RVRNSSNPNLVGT-HSA
AD--EKCIMSSKIA-----DRNCNRMSYYCSGNSDAPSSTAAPRPVSKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKQDNFRKTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRYFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTSPVSPCPSISSQNSSFCSSFQDQKIANIFD
LTSEYRQQHFLTGLLFTELAAALDAEGDGISRVQRKAVSAIHSLLSSHDLDPRCSKPEVK
LKIAALYLPLVGIILDALPQFYDFTVA-------------DARSGKNRSSGSDEEQD--S
AINQNIAQAIAGNHFNL-KTSGPL------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQTLLRRWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDAKARLEEALLRGEGARGEMMRRRTPXXXXXXX
XXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
--XASSALDCKDTLLGGILRVLVNSLSCDQSTTYLTHCFATLRALIAKXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYAEEDIAMQTTPFPIQVEEL-LRNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHSKKKCYTEAAMCLVHAAALVAEYLSMLEDH
NYLPVGSVSF-----------------------QNISSNVLEESAVSEDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFNTGGLYETVNEVYKLVIPILEAHRDFRKLSSTHDKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
SQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRI

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTAMHAFPYIKTRISVIHREEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQK---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MKSQWDVLNLVS---------------DARSGKGRTGNPEEEQESAG
AISQNVALAIAGNQFNL-RSSGTS------------------------------------
----LASL-SYRQSATLGPDTTRNLLICFLWIMKNADQNLIQKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQALQKSRDVKAKLEEALLRGEGARGEMMKRCRIPAGNDRS
AGLNENLRWRKEQTEWRQANERQDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASFAAECRDNLLGGVLKVLVNSLGCDQSTTYLTHCFATLRALIAKFGDFLFEEEVEQ
CADLCQRVLHHCSSSIDITRTQACATLYLLMRY

PF06920 // ENSGT00760000119234_3_Domain_2 (1714, 2267)

SFSSTSNFARVKMQVTMSLASLVGKSP
EFNEEFLRRSLRTILAYAEEDVDMQATPFPIQVEEL-LCNLNSILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDR
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDVLSPDEDGICS
GRYFSESGLVGLLEQAAELFNTGGLYETVNEVYKIVIPILEAHRDFRKLTLTHSKLQKAF
DSII---NKGQKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGEDNVEVIKDSAPVDKSKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLSRF
MYTTPFTMDGRPRGEL--SEQYKRNTILTTMHAFPYIKTRINIIQKEEFILTPIEVAIED
MRKKTQELTAATNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVNKNKHLITADQREYQQELRKNYGKLKENLRPMIERKIPELYKP
VVKVNS-SRESFRNHSFRKYDAQTSQST-

------------------------------------------------------------
MATLPSAER-------------RAFALKINRFSSAEIRKQFTLPPNFGQCHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

DSLDV-ELGQELGDFTDDDLDVVFTPKECRTLQP
SLPEDGVELDPHVRDCVHTYIREWLIVNQ--KNQGSSEIGGFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECAEPVAQTGPC-RLNVLCDVSGKGPFTAFDFDLRSLQPDQRLENLLQSVSSEDF
EKQNEEARRTNRQAELFALYPSVDKEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAIFSITYPS
SDIYLVVKIEKVLQQGEIADCVEPYIVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASLFSVSSLDREVTDAEPTVGRNSGGERRPLSQSRR-LSERTLSLEENGIGS
NFKTT---SMTINTFYKQEGDRLSDEDLFKFLADYKRSSSLQRRVKAIP--GLLRLEISP
APEVINGCLT--PEMLPVRPFPENRMRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEHPSNALPVIF-----G-KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTLNHHLLFTFYHISCK---QKEGASVESLLGYSWLPVLLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHALESQVTFPIRVLDQKITENVLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIASSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ERHRDASKSGGPTSL---PDPR-YHTYGRTSAAAVSSKLLQT-RVLSSSNPDLVGT-HSA
TDEEVKTIATSKAV-----DRNCSRMSYYCSGNNDAPGSTAIPRPASKKYFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNLDKSDSFRRTRFSDRFKDDITTIVNVVTS
EIGALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNIPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPVSPCPSVSSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEMK
VKVAALYLPLVGIILDALPQLYDFTDA---------------RSGKSRMNGSDEEQEGVS
AINQNVALAIAGNHFNL-KTSGTM------------------------------------
----LSSL-PYKQYSSLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKPSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDNLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDVLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQSTPFPVQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTNLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVAQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQRYQQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRQSFHRSSFKKCETQLSQGS-

------------------------------------------------------------
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-------------------------------VIFG------KSNGPEFLKEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCH---QKQGTSIESLLGYSWLPILFNERL
QTGPYCLPVALEKLPPSYSMHSPEKVPPQNSPFKWAEGHRGVFNIEVLAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKITEANLEHELKLSIICLNSSRLEPLVLFLHQILDKL
FQLSIQPMVIAGQTANFSQFAFESVVSIANSLHNSKDLSKDQHGRNCLLASYVYYVFRLP
NVHREVSKSVSPALQ---PDP-RYHTFGRTSVAAVNSKLLQA-RVMSNSNPDIAGI-HTS
PDEEVKNIMSSKAS-----DRVYNRMSYYSQGNNDTPSSTTVPRPASKKHFHEELALQMV
VSTGMVREAVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDVTTIVNVVTS
EIAALLVKPQKENDQAEKINISLAFFLYDLFSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMAP-DTAPASPNPSISSQNSSSCSSFQDQKIASMFD
LSSDYRQQHFLTGLLFTELAAVLDAEGEGITKVQRKAISAIHGLLSSHDLDPRCSKPEVK
VKVAALYLPLVGIIMDALPQLYDFTVS-------------DVRGGKGRPTNPDEEQEGGN
PVNQSVALAIAGNNFNPLKMSGAP------------------------------------
----LSSL-PYKQYNVLNPDTTRNLMICFLWIMKNAEQSLIRKWIADLPPMQLNRILDLL
FICVSCFEYKGKHNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCKTPAGNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALINGNLATEANLIILDMQENII----
--QASFALDCKDNLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSIDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAS
DFNEEYLRKSLRTILAYAEEDTAMQATPFPAQVEEL-LCNLNSILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHSKRKCYTEAAMCLVHAAALVAEYLSMLEDH
CYLPVGSVSF-----------------------QNISSNVLEESAVSDDILCPDEDGVCS
GRYFTESGLVGLLEQATELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTLTHDKLQKAF
DNII---NKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAKFVEVIKDSIPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--NEQYRRNTILTTMHAFPYIKTRIRVIQKEEFVLTPIEVAIED
MKKKTLELAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITSDQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVQNEKRNSFHRSSFRKYETQLSQGP-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTHLNNLDA-ELARELGDFTDDELDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYVREWFIVNG--KNQESSETCSFKKTGSRKEV--SLPKQTF
ESESVETTEPTAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXEDAVE--IRPIPECPREHLGNRVLVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDREVADAEPMIGRSSVGERRTLSQSRR-LSERALSLEENGVGS
NFKTS---TMTINNFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GVLRLEISS
APETIPGCLT--PEMLPVRPFPESRTRLHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASSAMPXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWLPILLNERL
QTGSFCLPVALEKLPPNYSMHSAEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXVKSMAQHVHNLDKGDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNSLPML
ISMRLEFLRILCNHEHYLSLNLLFMNA-DTAPTSPCPSVSSQNSSSCSSFQDQRIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAMHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAA-------------DARSGKNRTSGSDEEQEGAS
AINQNVVLAIAGSHFNL-KTGGTM------------------------------------
----LSSL-PYKQYNVLSADTTRNLMICFLWIMKNADQGLIRKWIADLPSMQLNRVLDLL
FICVSCFEYKGKQSSDKVXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXCRTP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDHEALLSGNLATEANLIILDMQENII----
--QASSALDCKDNLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRILHHCSSSMDVTRSQACATLYLLMRFSFGATSXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXVEELLCNLNSILYDTVKMREFQEDPEM
LMGLMYXXXXXXXXXXXLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX---XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX--XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF06920 // ENSGT00760000119234_3_Domain_3 (2189, 2270)

XXXXXXXXGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNRLRESLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSEEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLL

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTHLNSLDV-QLAQDLGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF
ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLEQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVTDVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPYK--EILEF--PTREVYVPHTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
AEEEVKNIMSSKIA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEVEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTVV-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GKDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 219)

NSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KSMK-PK

ENSGT00760000119234_3_Linker_0_1 (219, 648)

VCYSKKKKDK------------
----TH--CFLSQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEVGAAVSILE--SEDSESHVDNCIFFS-FYDRFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDASSLARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGLGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDACSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKIA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKQDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTVA-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNHFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSSTYLTHCFATLRALITKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRIESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
-------------------------------HSSAEIRKQFTLPPNFGQCHRQSIST-SG
FPSVQLPQFYDPVEPVDFEGLLMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNNLDV-ELAQELGDFTDDDLDVVFTPKECRTLQP
SLPEDGVDLDPHVRDCVHTYIREWLVVNR--KNQGSSENCSFKKTGLRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETVESVEPAAQTEPR-RLNVLCDVSGKGPFTAFDFDLRSLQPDQRLENLLQSVSSEEF
EKQNEEARRTNRQAELFALYPSVDKEDAVE--IRPVPECPKEHLGNRILVKFLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQLKGFLRAHTPSVDLSSQARSAIFSVTYPS
PDIYLVVKVGIPLYQQGILASIFWTYLITRGLIEYSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLAKS-------------EPQRWRNSGTERRSLSQSR-RLSERALSLEENGLGS
NFKTT---SMTINSFYKQEGDRLSDEDLFKFLADYKRSSSLQRRVKAIP--GVLRLEVSP
APEVISGCLT--PEMLPVIPVPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 837)

HTVYRNLLYVYPQ
RLNFANKLTSARNITIKIQFMCGEDPSNALPVIFG------KS----------------S
GSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---PKQGASVESLLGYSWLPIVLNERL
QTGSYCLPVALEKLPPNYFMHSAEKVPLQNPPIKWVEGHKGVFNIEVQAVSSVHAQ

ENSGT00760000119234_3_Linker_1_2 (837, 1718)

DIHL
EKFFTLCNSLESQVTFPVRVLDQKITENILEHELKLNIIHLNSSRLEPLVLFLHLVLDKL
FQLSVQSMFIAGQPANFSQFAFESVATIATSLHNSKDLSKDQHGRNCLLASYVHYAFRLP
EPHRDAPKSGGPPSL---PD-PRYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLSGS-HSA
ADEEVKNIMSSKAV-----DRTCNRISYYCSGNNDVPGSSAAPRPASKKHFHEELALQMV
VSTGMVRESVFKYSWFFFELLVKSMAQYVHNLDKSDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKEI--------SICFFLMA-------NFY----FSLSPQLSAKLSNIPTL
ISMRLEFLRILCSHEHYLNLNLFFMNT-DTAPASPCPSISSQNSSSCSSFQDPKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTD---------------ARGGKSRTNGSDEEPEGLS
AINQNVAQAIAGNHLNL-KTSGTM------------------------------------
----LSSL-PYKQYNTLNADTTRNLMICFLWIMKNADQSLIKKWIADLPSMQLNGILDLL
FICVSCFEYKGKPSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
QGLNENLRWRKEQTHWRQTNEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QVRTINTCFELILY------------------L------KFLLFVIFGDLLFEEEVEQ
CADLCQRVLHHCSSSIDVTRSQACATLYLLMRFSFGA

PF06920 // ENSGT00760000119234_3_Domain_2 (1718, 2267)

TSVRTQTCWV------TQIGR--
--------------------GSQCKTLPYTSLQVEELLCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLASTHDKLQKAF
DHII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEHAA
PL-FA----A-----WLISSSPCLPLQAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--QEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDCSPAKILG----PFNIKRGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKESLRPMIERKIPELYKP
IFRVESQKRESFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------D
IEPLFASFALYDLKEKKKISENFHCDLNSEVYKGYLRNHIPNIATSSQAKSAVFSITYPS
QDIFLVVKIEKVLQQGEISDCAEPYMVLKETESGKFAVKVSES---APEGCKV-----LN
YAYIPLCTM--------------------------KRASWTAGRRFSDRCNSLEEN----
---------TQIGAIYEQEGDKLSDEDLFKHLADYKRS-SLQRRIKSIPEFLGVTQP---
---SITCNFFSHLNTLPTIHFMTCSKKPCTRFEISKFIFLRPQHTYCITYFRNILYVYPQ
RLNFANRLSSARNIAIKIQFMNGEDAKNAMPLKVIFG----KSSGPEFLSEVTTAVTYHN
KTPDFYEEVKIKLPAKLTNRHHLLFTFYHISCQ---SKQGACVETLLGYSWLPMLLNDRL
QIGQYCLPVAMEKLPLNYSMHTPEKVPGQSPPIKWVEGHKGVFDLEVQAVSSVHTQDNHL
EKFLTLCHALE-------------------------------------------------
--------------ANFSQYAFESVVSIVNSLHNINHGF-----MVCLQPEYFRSH--LI
RMHKST------------KEPAKHFT------LHLSKKFLHCM-------------CV--
-------------------AGNLPEMRYYTVIKI-WARQQAYMDVAAYKHFHEEMALQMV
VSTGMVRESVFKYAWFFFELLVKSMALYVHSVDKQDVPRRSRFSDRFKDDISTIVNVVTS
EIGSLLSKPQKALDMAPHYRYG-------SLKICY---QWYTVSFIFCGLTSKLNSFPTL
ISMRLEFLRILCSHEHYLNLNLFFVCG-NG-----------------QLERDQKIASMFD
LSPDYRQKHFLTGLLFTELDAALDSEMEGIGKVQRKAIGAIYNLLSSHDLDPRCQRIETK
QKIADLYLPLVSTILDALPQLHDFSEYKYGLIIYIKGEAVDTRSGK--ARTSDEESETPS
TINPSVAMAVAGNQFNIKTSTISSVFCLQSAPSQAGTLSTYSLHVLIVPPKHPGTSEDSL
VLQFMFLKQPVKVYSTLSPESSRILLTCFLWIMKNAEQNVIQKWITYMPILQLNRILDLL
YMCVSCFEYKTKSAPWCFRNQEMLRHA-------------------WKKHCLGV-KAPGI
PCAESVMQPLPSL--SPFPHCSIVMTKAEIEQEAIMCRNLATEANVTILDIKKAVNLHVM
RFKNYLSIDCKDNLLGGVLKVLVHSLSTNQSNTFLTHCFSTIRLLIIKFADFLFEEEVEQ
CSDLCQKVLHHCCSSLESTRSQACATLYLIMRFSFSNISNFARVKMQVTMSLASLVGKSQ
DFNEEFLRKSLRTILAYAEEDEEMQPTLFPAQVDDL-LNNLNSILSDTGETKVRITNSAL
VYFTRIRIAKGYQTSPDLRLTWLQNMAEKHVKRKCFTEAAMCLVHAAALVAEYLGMLEDC
SYLPVGSVSFQASLSLLLCWFNPNLTSQLSVSYQNISSNVIEESAVSDDILTPDDDGVCS
GRYFSENGLIGLLEQAAELFNTAAFYETVNEVYKIVIPVLEAHRDFHKLASTHKKLQKAF
DNIAEKVSHGQKRMFGTYFR---VGFYGSKFGDLDEQEYIYKEPTITKLPEISHRLESFY
GQCFGDDAVEVIKDSVPVDKSKLDPNKAYIQITFVEPYFEDYEKKYRA

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

THFEKNYNLRRF
MYTTPFTLDGRPRGEL--SEQYKRKTILTTIHAFPYIKTRINVIQKEEFELTPIEVAIED
MQKKTHELADATNKEPPDAKMLQMLLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKI------
-----------------------------

------------------------------------------------------------
------------------------------RYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHLNSLDV-ELAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEICGFKKTGSRKDFHKTLQKQTF
ESETLESSDPTTQTGPR-HLNVLCDVSGKGPVTACDFSLRSLQPDQRLENLLQHVSSEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKMLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVATSSQARSAVFSVTYPS
SDIYLVVKXXXXXXXXXXXXXXXPYMVI-ESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVEPMVXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXX---XXXXXXXXXXEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEISS
APEVVSGCLT--PEMLPVTPFPENRTRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASAALPVIFG------KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPVQNPPIKWAEGHKGVFNIEVQAVSSVHTQXXXX
XXXXXXXXXXXXXXXXXLRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGGPAAL---PDP-RYHTYGRTAAAAVSSKLLQA-RVMSSSNPDLTGT-HSA
ADEEVKNIMSSKXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKP-DFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNT-DTAPTSPSPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISRVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAA-------------DARGGKSRPNGADEEQDGAS
AINQSVALAIAGNHFN-LKTSGTM------------------------------------
----FS-S-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRRTPX-XXXXX
XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXNLATEANLIILDMLENII----
--QXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFGDLLFEEEVEQ
CADLCQRVLQHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRKSLRTILAYSEEDTAMQSTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-----------------------XNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLT-THDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXAYIQITFVEPFFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTSHAFPYIKTRIRVIQKEEFVLTPIEVAIED
MKKKTLQLAVAVNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLRENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCDTQLSQGS-

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQDLGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPTAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLEQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNVMSSKIA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEVEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTGV-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLAGRPRGEL--HEQHRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTHLNSLDV-ELAQELGDFTEDDLDVVSTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-X-XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXEDAVE--IRPVPECPREHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKDKVEKLKLQAESFCQRLGKYRMP
FAWAPVSLSSFFNVSTLDREAPDTEAMIGRGSIGERRTLSQTRR-LSERALSLEENG--S
SFKTT---TLNINTFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEVSP
APETLSGCLT--PEMLPVRPCAENRTRLHK--EILEF--PVREVYVPHTTYRNLLYVYPQ
RLNFTSKLASARNITIKVQFMCGEDASNAMPVIFG------KSNGPEFLQKVYTAIMYHH
KSPDFYEEVKIKLPAKLTANHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTQSYCLPVALEKLPPNYSIHSAEKIPLQNPPVKWAEGHKGVFNVEVQVISSVHTQDNHL
EKFFTLCHSLESQVTFPLRVLDQKISENMLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXGPTP---VP-DPRYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKSIMSAKIA-----DRNYNRVSYYSAGSSDTPSPTSAPRPASKKXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXVKSMAQYIQNMDKQDDFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENA-AVKNNISLAFFLCGLLSLMDQGFMFNLIKHYNWLL-AKCSNIFML
ISM-LEFLQVLCSHEQSFNLNLLFMNN--TVPALPCPFMSSQNSSSASSLQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXA-------------DARGGKGRGSGSDEEQEAGS
TINQNVALAIAGNNFSL-KTSGIT------------------------------------
----LSSL-PYKQCSLLSADTTRNLMICFLWIMKNADQSLIRKWIADLPGMQLSRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR--RTPGNDRF
PGLSENLRWRKEQTHWRQAAEKLDKTKAELDQEALISGNLATEANLIILDTQENII----
--QATSALDCKDNLLGGVLRVLVNSLSCNQSTTYLTHCFATLRALISKFGDLLFEEEVEQ
CADLCQRVLHHCSSSIDVTRSQACATLYLLMRFSFGAVSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYAEEDTAMQTTLFPIQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKTKCYTEAAMCLVHAAALVAEYLSVLEDR
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVLPILEAHRDFRKLTSTHSKLQKAF
DSVI---NKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTRLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

THFEKSFNLRRF
MYTTPFTLEGRPRGEL--QEQHQRNTVLTTLHAFPYIKTRITVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGTTVNQXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXCGEAVEKNKRLITADQREYQQELKKNYHKLKENLRPMLERKIPELYKP
LFRVESQKRDSFHRSSFRKCDTQLSQDS-

------------------------------------------------------------
------------------------------------------------------------
----------------------

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTHLNSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNQ--KNQGSPEICGFKKTGSRKDFHKTLPKQTF
ESETLECSEPAAQAGPC-HLNVLCDVSGKGPITACDFDLHSLQPDKRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLNLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDGGKSKEKIEKVKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLDREV-------TRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVPHTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASNAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
EVQRDVPKSGAPTAL---PDPRSYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLVGT-HSA
ADEEVKNIMSSKIT-----DRNCSRMSYYCSGNSDVPSSTAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPML
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTVA-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYHKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

----------------------------------------------------------MA
TLPSAERRA-------------F-AL-KINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYEPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

SSLDV-ELAQELGDFTDDDLDVVFTPKEFRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNQ--KNQGSSEICSFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECNEPTTQTGPR-RLNVLCDVSGKGPLTACDFDLRSLQPDQRLENLLQHVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILIKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQLKGFLRAHTPSVATSSQARSAIFSVTYPS
SDIYLVIKIEKVLQQGEIGECAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLATFFNVSTLDREVMDVEPTVGRSSVGERRTLAQSRR-LSERALSLEENGVGS
NFRTT---TMTINTFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--VSLKLEISS
APETINCCLT--PEMLPVRPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 837)

HTVYRNLLYVYPQ
RLNFASKLASARNITIKIQFMCGEDASNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---PKQGATVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAE--------------------------------

ENSGT00760000119234_3_Linker_1_2 (837, 1713)

DNHM
EKFFTLCHCLESQVTFPIRVLDQKICEAALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDLPKSGAPPAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGTAHSA
ADEEVKNIMSSKIA-----DRNCNRMSYYCSGNNDVPSSTAAPRPASKKHFHEELALQMV
VSTGLMRETVFKYAWFFFELLVKSMAQYVHNMDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKSQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQ-----------
------------------------------------------NSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDVEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDTLPQLYDFTAA-------------DVRSGKSRTNGSDEEQEGVS
AINQNVALAIAGNHY--LKPSGVM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWVMKNADQSLIRKWIADLPSMQLNRILDLL
FLCVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RTP-GNDRF
SGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLGCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKSKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRIAVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITADQREYQQELKKNYNKLKESLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

----------------------------------------------------------MA
TLALKDCR--------------QRFFCFNPRYSSAEIRKQFTLPPNLGHYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLL

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTHLNSLDV-ELAQELGDFSEDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSDICSFKKTGSRKDFHKTLQKQTF
ESETLESSEPSAQAGPR-HLNVLCDVSGKGSNTACDFDLRSLQPDPRLENLVQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVAKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDREVTDVESTVGKGSAGERRTLSQSRR-LSERAFSLEENGVGS
NFRT-----LTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPDLGLLRLEIAL
APETISCCLT--PEMLPVRPFPENRGRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
SLNFTNKLASARNITIKIQFMCGEDASSAMPVIFG------KSNGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGNSVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPSQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLEQKITESALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLFVQPMVIAGQPANFSQFAFESVVVTANSLHNSKGLGKDQHGRNCLLASYVHYVFRLP
EPQRDMPKSGGPTVL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLTGP-HCA
ADEEVKNIMSSKIA-----DRSCNRMSYYCSSNSDAPSSTTAPRPVSKKHFHEELALQMV
VSTGMVKETVFKYSWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLLKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKVAALYLPLVGIILDALPQLYDFTAA-------------EARGGKNRASGSDEEQEGTS
AINQNVALAIAGN-FN-LKTSGTV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLLRRWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSGMDITRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAQ
DFNEEYLRRSLRTILAYAEEDTAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHEKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEKEFVYKEPAITKLPEISHRLEAFY
SQCFGTEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRL

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTILTTLHAFPYIKTRISVAQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYGKLKENLRPMIERKIPELYNP
LFSSLLNFRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------FLTV
LGIE------------------------PRASALTEIRKQFTLPSNLGQCFRQSIST-SG
FPSVQLPQFYDPVEPVDFEGLLMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDV-ELAQELGDFTDDDLNVVFTPKECRTLQP
SLPEDGVDLDPHVRDCVHTYIREWLIVNR--KNQGSSEICGFKKTGSRKDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESET-ECAEPAAQKGPR-RLNVLCDVSGKGPFTAFDFDLRSLQPDQRLENLLQSVSSEDF
EKRNEEARRSNRQAELFALYPPVDKEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFYCDLNSDQFKGFLRAHTPSVDLSSQSRSAIFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYIVYKEGDGGKNKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDREVTDVEPTLGKIFICSGKGLFPSVQALTSTGLR---KIPGC
EFRNQRSIYSNPVWFSSQEGDRLSDEDLFKFLADYKRSSSLQRRVKAIP--GVLRLEISP
APEVINGCLT--PEMLPVIPFPENRSRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLTSARNITIKIQFMCGEDNGDAMPLVF-----P-STQGGLYLC----IMCFQN
RSPDFYEEVKIKLPAKLTVHHHLLFTFYHISCQ---PKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPFNYSMHSAEKVPLQIPPIKWAEGHKGVFNIEVQAVSSVHTQDS

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESRVTFPIRVLDQKVPENMLEHELKLSLICLNSSRLEPLVLFLHLVLDKL
FQLSVKSMVIAGQTANFSQFAFESVAAIASSLHNSKDLSKDQHGRNCLLASYVHYAFRLP
EPHGGAPKSGGSASL---PSPG-YHTYGRTSAAAVSSKLLQA-RVISSSNPDLMGT-HSA
TDEEVRNIMSSKAV-----DRNCSRMSYYCPGSNDAPGSSAAPRPASKKHFHEELALQMV
VSTGMVRESVFKYAWFFFELLVKSMAQYVHNLDKSDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNIPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPASPSPSLSSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGDGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTDA-------------R--SAKSRVNGSEEEAEGVS
AINQNVAQAIAGSQFNL-KTSGTM------------------------------------
----LSSL-PYKQYNTLNADTTRNLMICFLWIMKNADQSLIKKWIADLPSMQLNGILDLL
FICVSCFEYKGKPSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRGP-GNDRF
PGLNENLRWRKEQTHWRQTNEKLDKTKAEIDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDITRTQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQSTLFPVQLEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAGALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAISDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKMVIPILEAHRDFRKLASTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFTIESQKRESFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------------------------------------
----------------------MTHLNSLDV-ELAQELGDFTEDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYVREWLIVNQ--KNQGSSDTCGFKKSGSRNDFHKTLQKQTF
ESETLECSEPSSQTGPR-HINVLCGVSGQRPLTAYGFDLRSQQPDQRLENLLQHVRAEDF
EKQMRA--RTTNRAELFALPSXXXXXXEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAPSSQARSAVFSVTYPS
SDIYLVVKIEKVL-QGEIGDCAEPYMVIKESDGGKSKEKVEKLKAQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLEREVTDMEAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X-XXXXXXX--XXXXXXXXX
XXXXXXXXXX--X-XXXXXXXXXXXXXXXX--XXXXX--XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVIF------GKSNGPEFLQEVYTAITYHN
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXKVPLQNPPIKWAEGHKGVFNIEVQAVSSIHTQXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXGPA---PLPDP-RYHTYGRTSAAIVSSKLMQA-RVMSSSNPDLAGA-HSA
ADEEVKSIMSSKIA-----DRNCNRMSYYSCGNNDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSFRRTRFSDRFQDDITTIVNVVTS
EIAALLVKPQKENEQAEKVNISLAFFLYDLLSLMDRGFVFNLIKHYCNQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXISRVQRKAVSAINSLLSSHDLDPRCVKSEVK
VKIAALYLPLVGIILDALPQLYDFTAV-------------DAHSGKNRANGSDEEQDGAS
AINQNVALAIAGNHFNL-KTSGTM------------------------------------
----LSSL-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXFEYKGKPSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRTP-GNDRF
PGLNENLRWRKEQTHWRQAAEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEHLRKSLRTILAYAEEDMAMQTTPFPMQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
CYLPVGSVSF-----------------------QNISSNVLEESAVSDDILSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVTPILEAHRDFRKLTSTHSKLQKAF
DSII---NKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAESVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--QEQFRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MK-KTLQLAVAINQEPPD-KMLQMVLQCSV-ATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKHLITVDQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

MPPFPRRRRLRLPHVAAWSWSLPLAFGLLSTRKGAKAEAPALLAALAGLHASAPPPFHAR
SGQPGAGLGADACMATLPAADRRAFALKINRHSSADIRKQFVNQLNLGQIPQRSISS-PG
FSTVHLPQFYDAVEPVDFEGFLMM

PF11878 // ENSGT00760000119234_3_Domain_0 (145, 241)

QLNNLDS-ELLQELGDFPEDDLEVAFTPKEHRTLQP
SLPEEGAELDPHVRDCVQTYVRDWLIVNR--KNQGNNEVYTFTKRGSRRDFHKTLQKQTF
ESEVLDYSNSNYQACPR-HLKVLCDESNRATLTSGDFDLRSLQPDPHLPSLLQPVSAENL
KRQNEEARQSNRPTELFALYPSIDEEDAVE--IRPVPECPKEYLGNRLLVKIQTLKFEIE
IEPLFASLALYDIKERKKISENFHCDLNSEQFKGFLRSHTPCVDSSSLARSAVFSVTYPS
PDIYLVIKIEKVLQQGEIGECAEPYMVLKESDGGKTKEKVEKLKSQAESFCHRLGAYRMP
FAWVPISLGSFFSISTLERDIAELEVLNGKGSTGDRKTMTMQTRRLSERSLGIEDVSSMT
NFKPT---TLTVNTFFKQEGDKLSDEDLFKFLADSKRSSSLQRRVKSIP--GLLKLEISP
ASEALTCCLS--PELLPVKPFPENRSRPHK--EILEF--PVREVYDPHTVYRNLLYVYPQ
RLNFANRLASGRNITIKIQFMCGEDPSCAMPIIFG------KSSGPEFVKEVCTSVTYHN
KSPDFYEEVKIKLPAKLTERHHLLFTFCHISCQ---HKQGGCVETLLGYSWLPILLNDRL
QTGHYCLPVALDKLPANYSMHSAEKVPPQSPPIKWVEGHKGVFNVEVQAISSVHTQDNHL
EKFFTLCHALESQVAFPIRVLNEKITEATLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLAVQPMVIAGQTANFSQFAFESVVATVNSLHNSKDLSKDQHGRNCLLASYVYYVFRLP
EIQREVVKLGTSGGVNLP--ESRYYTYGRTTAVSVGSRLLQS-RATSCSNPDIAGT-QTA
TDEEVHNIMSSRIV-----DRSYNRMSYYSEPSSDMSSPCTSPRPSSKKHFHEELALQMV
VSAGMVRESVFKYSWFFFELLVKSMAQYVDNMEKRDTPRRSRFSSRFKDDITTIVNVVAS
EVAALLVKPQKESEQAEKMNISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSNKLNTVPTL
ISMRLEFLRILCSHEHYLNLNLFFLTS-SSAPTSPSPSLSSQNSSSCSSFQDQKLANMFD
LTADYRQQHFLTGLLFTELTAALDTEAEGISRVQRKAVSAIHSLLSSHDLDKSCLKPEVK
VKVAALYLPLVGIILDALPQLHDFTVS-------------DGRNGKGRSGSPDEEQEAAS
QINQNIALAIAGNQFNLLRSSGSS------------------------------------
----VSAV-PYKYYNTLSPETTRHLLICFLWIMKNADQKLIQKWISDLPSMQLNKILDLL
FICVSAFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMKRCRMPVGNERF
PGLNENLRWKKEQTHWRQANERLDKTKAEIDQEALVSGNLATEANLIVLDMQENII----
--QATSAMDCRDNILGGVLKVLVNSLTCDQSTTYLMHCFATLRALIVKFGDLLFEEEVEQ
CADLCQRVLQHCSSSIDATRIQSCATLYLLMRYSFSSTSNFARVKMQVTMSLASLVGKAS
DFNEEYLRKSLRTILAYAEEDTDMQPTLFPAQVEEL-LCNLNSILSDTVKMREFQEDPEM
LMDLMYRIAKGYQTSPDLRLTWLQNMAEKHAKRKCYTEAAMCLVHAAALVAEYLSMLEDH
NYLPVGSVSF-----------------------QNISSNVLEESAVSDDVLSPDEDGVCS
GRYFSENGLVGLLEQAAELFSTGGLSETVNEVYKIVIPILEAHRDFRKLSSTHSKLQKAF
ENII---NKGQKRMFGTYFR---VGFYGAIFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGEDRVTVIKDSTPVDKSKLDPSKAYIQITFVEPYFDDYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

THFEKNFNLRRF
MYTTPFTRDGRPRGEL--SEQYKRKTILTTMHAFPYIKTRINVIQKEEFVLMPIEVAIED
MQKKTLELAVATNQVPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPEDSKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITVDQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IVKIDSISRDSFRNSSFRKTENLPPQSA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------MP
FAWIPISLTNFFNVSTLEREVSEAEGLNGKGSTSDKRATLLQARRLSERSLSTEDSYPVS
NFKTV---SLTHSTFFKQEGDRLSDEDLFKFLADFKRSSSLQRRIKTLP--GTLKLEISP
APENLGYCLT--PELLPVKPFPENRSRPHK--EILEF--PIKEVYVPH

PF14429 // ENSGT00760000119234_3_Domain_1 (649, 839)

TIYRNLLYVYPQ
RLNFANRPASARNITIKIQFMCGEDPSCAMPVIFG------KSSGPEFVQEMYTAITYHN
KSPDFYEEVKIKLPAKLTEKHHLLFTFYHISCQ---PKQGASVETLIGYSWLPILLNDRL
QTGHYCLPVALDKLPFHYSIHSPEKVPSQTPPIKWVEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRLMDQKITEATLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLAVQPMVIAGQTANFSQFAFESVVAIVNSLHNSKYLSKDQHGRNCLLASYVYYVFRLP
DPQKEVPKLGAGGSAALT--ESRYYTFGRTSAVSVGSKLLQS-RVISCSNPDITVT-QTA
ADEEVKNIMSSKPA-----DHSSSRMSFYIEGTNDMPGVCTNPRPSSKKHFHEELALQMV
VSTGMVREAVFKYAWFFFELLIKSMAQYVHSIEKQDNVRRSRFSDRFKDDVTTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSNKLNSLSTL
ISMRLEFLRILCSHEHYLNLNLFFMTS-ASTPASPSPSLSSQVGIHQPIL------GGLH
LNNAC-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

--------------------------------------------------------QDTL
----L------------------LMQYRSFVLDSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NTLDV-QLAQELGDLTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCIQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESESLECSEPDAQTGPR-HLNVLCDVSGKGPLTACDFDLRSLQPDQRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKEGDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFLNVSTLEREVTDVDPVVGRSSAGERRTLAQSRR-LSERALSLEENGAGS
NFKTS---TLSVNSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVRPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDAGNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGGSVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
EPQRDMPKSGAPTAV---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKAE-----SIPSN-----------------TSLLRSSGHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSVRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFTLIRHYCNQLSAKLNNLPML
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISRVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLSDFAAL-------------R--HWKSRTSGSDEEQEGPS
AINQNVALAIAGNHFNL-KTSGMM------------------------------------
----LSSL-PYKQYNMLNADTTRSLMICFLWIMKNADQSLIRKWIADLPSVQLNRILDIL
FICVFCFAYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMIRR-RA-PGNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVRSLNYDQSTTYLTHCYATLRALIAKFGDLLFEEEVEQ
CANLCHQVLHHCSSSMDVTRTQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLAFLVGRAP
DFNEEHLRRSLRTILAYLEEDTAMQMTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCV
GQYFTESGLVGLLEQASELFSTGGLYETVNEVYKLVIPILEEHREFRKLTLIHSKLQRTF
DSIV---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPHKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQVPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFILRCGEAVEKNKRLITPDQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

----------------------------------------------------------MA
TLPSAERRA-------------F-AL-KINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPPFYDPVEPVDFEGLL

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTHLNSLDA-DLAQELGDLTDDDLDVVFTPKECRTLQP
SLPEEGVDLDPHVRDCVQTYIREWLIVNR--KNQGSSEICGFKKTGSRKDFHKTLQKQTF
ESETLENAEPTAQAAPR-HLNVLCDVSGKGPLASCDFDLRSLQPDARLENLLQHVSSEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHMGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFRGFLRAHTPSVAPSSQARAAVFSVTCPS
SDVYLVVKIEKVLQQGEIGECAEPYMVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLDREAADVEPVVGRSSVGERRTLSQTRR-LSERALSLEENGVGS
NFKTT---TMTVNNFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEVSP
APETISCCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASSAMPVIFG------KSTGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTIHHHLLFTFYHISCQ---QKQGAAVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELPRDLPSTGGTPAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKIG-----DRNCNRMSYYCSGNNDVPSSPAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKLQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNSLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQRIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAA-------------DARGGKSRTSGSDEEQEGAS
AINQSVALAIAGNHLN-LKTGGSM------------------------------------
----LSSL-PYKQYNMLSADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLNENLRWRKEQTHWRQANEKLDKTKAELDHEALLSGNLATEANLIILDMQENII----
--QASSALDCKDNLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEVHLRRSLRTILAYSEEDVAMQATPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDR
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DSII---SKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
SQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

THFEKNFNLRRF
MFTTPFTLEGRPRGEL--HEQYRRNTVLTTTHAFPYVKTRIRVAHKEEFVLTPIEVAIED
MKKKTLQLAVATNQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLRESLRPMIERKIPELYKP
IFQVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------RYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NTLDV-QLAQELGDLTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCIQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPDAQTGPR-HLNVLCDVSGKGPLTACDFDLRSLQPDQRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPTVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIRESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDPVVGRSSVGERRTLAQSRR-LSERALSLEENGVGS
NFKTS---TLSVNSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEVST
APEIINCCLT--PEMLPVRPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 805)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDAGNAMPVIFG------KSSGPEFLQEVYAAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGGSVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAE

ENSGT00760000119234_3_Linker_1_2 (805, 1713)

VIGNRGLGPP----SQN-------------------
-HFSFPCDQTCSSCSLEHTVFSEKTS------------------TTGPL-----------
RSSCGATHFSLGSSANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
EPQRDMPKSGAPTAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVLSSSNPDLAGT-HSE
ADEEVKNIMSSKVA-----DRNCSRMSYYCSGNNDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSVRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFTLIRHYCNQLSAKLSNLPML
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTVPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISRVQRKAVSAIHSLLSSHDLDARCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAT-------------R--CWKSRTSGSDEEQEGAS
AINQNVALAIAGNHFNL-KTSGMM------------------------------------
----LSSL-PYKQYNMLSADTTRSLMICFLWIMKNADQSLIRKWIADLPSVQLNRILDIL
FICVFCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RA-PGNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVRSLNCDQSTTYLTHCYATLRALIAKFGDLLFEEEVEQ
CANLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLAFLVGRAP
DFNEEHLRRSLRTILAYLEEDTAMQMTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCV
GQYFTESGLVGLLEQASELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLIHSKLQRTF
DSIV---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPHKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQVPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFILRCGEAVEKNKRLITPDQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------RHSSVDIRKQATLPPNFGQSHRQSIST-SG
FPSLQLXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXVELDAHVRDCVQTYVRDWLIVTR--KSQGGWEPCGLRKTGSRKDFHKTLQRQTF
ESEASENAEPSTEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX-XXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXISENFHCDLNSDQLRGFLRAHTPSVATSSQARSAVFSVTYPS
SDIL-VVKXXKVLQQGEIGDCAEPYLVIRESEGGKNKDKTEKLKLQAEAFCQRLGKYRMP
FAWAPLSLNSFSNISSLDREGPDTEAAVGRGPVGERRTLSQSRR-LSERALSLEENGFMS
SFKTT---PLTITNFFKQEGDRLSDEDLFKFLADYRRSSSLQRRVKSIP--GLLRLEVSP
APDTLPGCLT--PEMLPVAPSSENRTRPHK--EILEF--PIREVYVPHTVYXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVIFG------KSNGPEFLQEVYTAITYHN
KSPDFYEEVKLKLPAKLTTSHHLLFTFYHVSCQ---QKQGGSVESLLGYSWLPILMNERL
QTGSHCLLIALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFSVEVQAVSSVHTQDNHL
EKFFTLCHALESQVTFPLRVLDQKVSEAALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLXXXXXXXXXXXXNFSQFAFESVVAIVNSLHHSKDLSRDQHGRNCLLASYVHYVFRLP
EPHRDLPKSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------XXXXXXXX
XXXXXXXXXXXXXXXXXIPDRNCNRVSYYSSGSSDAPGSAAAPRPASRKXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXVKSMAQYVHNLDKKDHFRRARFSDRFKDDITTIVNVVTS
EIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCHQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXNSSSGSSLPEHKVASMFD
LTPEYRQQHFLTGLLFTELAAALDADGEEVSKVQRKAVNAIYSLLSSHDLDPRCARPEVK
VKVAALYLPLVGIILDALPQFYDFTXXXXXXXXXXXXXXXXXXXX-------------XX
XX---X-XXXXXXXX----------------------------------------XXXXX
XXXXXXXXXPYKQCSVLSADTTRSLMLCFLWILKTAEQSLVRRWVADLPSLQLTRILDLL
FLCVSCFEYKGKQSSDKVSTQVLQKSRDAKARLEEALLRGEGARGEMMRRCRTP-GNDRF
PSLSENLRWR-EQTHWRQANEKPDKTKAELDQEALVSGNLATEASLIILDMQENII----
--QASSALDWKDSLLGGVLRVLVNSLSCDQSTTYLAHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRLLHHCSSGLHTTRRQACATLYLLMRFSFGAVSNFARVKMQVTMSLASLVGKAP
DFNEEHLRKSLRTILAYAEEDAAMQATLFPSQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------X-------
---------XXXXXXXXXXXXXXXXXXXXXXXXXNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHSKLQKAL
DSVL---SKGQKRMFGTYFR---VGFYGSKFGDLADQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDRSKLDPNKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF06920 // ENSGT00760000119234_3_Domain_3 (2149, 2196)

FVLTPIEVAIED
MKKKTLQLAVAVNQEPPDAKMLQMVLQGSVGATVNQXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXDSSHRSSFRKCETQLSQGN-

------------------------------------------------------------
-------------MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSLST-SG
FPSLQLPQLYEPVEPVDFEGLVMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDA-ELAQELGDLTDDDLHVAFTPKECRTLQH
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEFCSFRKTGSRRDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPATQTGPRHRFNVLCDVSGKGPITSCDFDLRSLQPDERLENLLQL-SAEDF
EKEKEEARKTNRTAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLERESTDLEPGAGRNSVGERRSLSQSRR-PSERTLSFEENGVGS
NFKTT---TLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEIAP
APDVMNCCLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASGESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKITENTLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLP
ELHRDAPKSGGPTAVV--P-DPRYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLAGT-HCA
ADEEVKNIMSSKIAD-----RNCSRMSYYCSGNSDVPGSTAAPRPVSKKHFHEELALQMV
VSTGLVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCTQLSAKLNTLPTL
ISMRLEFLRILCSHEHYLNLNLLFMNP-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------DARSGRSRASGSYEEQDVAN
GINQNVALAIAGNHFNL-KTSGAM------------------------------------
----LSSL-PYKQYNMLNADTTRHLMVCFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRR-RIP-GTDRF
PGLNENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSSLDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMALASLVGKAP
DFNEEHLRKSLRTILAYSEEDTAMRATLFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIED
MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNRLKDSLRPMIERKIPELYKP
IFRVDSQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
-------------MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSISA-SG
FPTLQLPQLYEPVEPVDFEGLVMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

DSLDA-ELAQELGDLTDDDLHVAFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSSEFCSFKKTGSRRDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQTGPRQ-LKVLCDVSEKGPLTTCDFDLRSLQPDERLENLLQLLSAEDF
EKKKEEARKTNRPAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLERESNDMETVVGRNSVGERRSLSQSRR-PSERSLSLEENGVGS
NFKTT---TLATSIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEVSS
APDVMNCCLT--PEMLPVKPFPENRTRPHK--EVLEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASGESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLP
ELHRDAPKSGGPA-AI--P-DPRYHTYGRTSAAAVSSKLIQA-RVMSSSNPDLAGA-HCA
ADEEVKNIMSSKIAD-----RNCSRMSYYCSGNNDATGSTAAPRPVSKKHFHEELALQMV
VSTGLVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNTLPTL
ISMRLEFLRILCSHEHYLNLNLLFMNT-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDSEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVK
VKIAALYLPLVGIILDALPQLYDFTVA-------------DARSGRSRASGSYEEQDVAN
GINQNVALAIAGNHFNL-KTSGAM------------------------------------
----LSSL-PYKQYSMLSADTTRHLMICFLWIMKNADQSLIRRWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRR-RTP-GNDRF
TGLNENLRWRKEQTQWRQANEKMDKTKAELDQEALISGNLATEANLITLDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMALASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPTQVEEL-LYNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRIQVIQKEEFVLTPIEVAIED
MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELRKNYNKLKDSLRPMIERKIPELYKP
IFRIDSQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
------------------------------RYSSVEIRKQFTLPPNLGQYHRQSLST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHLNSLDV-ELAQELEDFTEDDLDVLFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNRKKRNQGSSEICGFKKTGSRRDFHKTLQKQTF
ESESLESREPSTQARPR-HLNVLCDVSGKVPLTACGFDLRSLQPDQRLENLLQQVSAEDF
EKQNEEARRTNRHAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAPSSQAKSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKEGDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLTSFFNVSTLEREVTDVESMVGRSSVGERRTLSQSRR-LSERALSLEENGVGS
NYKTT---TMTVNSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEISS
APEIINCSLT--PEMLPVKPFPENRTRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDASNAMPVIF-----G-KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISETSLEHELKLSLICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLAKDQHGRNCLLASYVHYVFRLP
EPPRDPPKSGGAATL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HCA
ADEEVKNIMSSKNA-----DRNCNRMSYYCSGNNDVPGSTATPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
ETAALLVKPQKENEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLTNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELVAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTAA-------------DARSGKNRANGSDEDQEGIS
AINQNMALAIAGNNFTS-KTSGTM------------------------------------
----LSSL-PYKQYNMLSADTTRNLMICFLWIMKNADQSLIKKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLSENLRWRKEQTHWRQANEKQDKTKAELDQEALISGNLATEANLIILDMQENII----
--QATSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEYLRRSLRTILAYAEEDIAMQATPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEHAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGEEFVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--QEQYRRNTVLTTMHAFPYVKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAIHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYHKLKENLRPMIERKIPELYKP
IFRVESHKRDSFHRSSFRKCETQLSQGS-

----------------------------------------------------------SA
TT-EGDQKG-------------FTAIKFNPRYSSAEIRKQFTLPPNLGQYHRQSISTSAG
FPSLQLPQFYDPVEPVDFEGLLMTHLNNLDV-ELAQELGDFTEDNLDVVFTPKECRTLQP
SLPEEGVELDPHVKDCVQTYVREWLILNQ--KHQGNSEICRFKKIGSRKDFHKTLQKQTF
ESEILECSEPRVQAGPR-PLKVLCDVSGKGPLTAFDFNLRSLQPDQRLENLLEHVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRIWVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFNVSTLEREVTDAESVVGRSSVGERRTLSQSRR-LSERALSLEENGVGS
NFKTT---SMTINSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEISQ
APEIINCCLT--PELLPVKPFSENRTRPHK--EILEF--PIREVYVPHTVYRNLLYVYPQ
RLNFTNKLTSARNITIKIQFMCGEDPSNAMPVIFG------KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASIESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISETTLEHELKLSIIWLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQKDLPKSGGPTAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLTGT-HSA
ADEEVKNIMSSKIA-----DRNCNRMSYYSSGNNDVPSATGAPRPTSKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKQDNFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKETEQAEKINISLAFFLYDLLSLMDRSFVFNLIKHYCNQLSAKLNNLATL
ISMRLEFLRILCSHEHYLNLNLFFMSA-DTAPASPCPSISSQNSSSCSSFQDQKIANMFD
LTPEFRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKVAALYLPLVGIILDALPQLYDFTAA-------------DARSGKNRASGSDEEQDGTS
GINQNVALAIAGNHFN-LKTNGPM------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLSRILDLL
FICVSCFEYKGKPSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RVP-GNDRF
SCLNENLRWKKEQTNWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGAISNFARVKMQVTMSLASLVGKAQ
DFNEEHLRKSLRTILAYAEEDKAMQTTLFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHSKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSEDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTCTHDKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
SQCFGAESVEVIKDSAPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAIHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPDLYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
-------------MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSIST-SG
FPSLQLPQLYEPVEPVDFEGLVMTH

PF11878 // ENSGT00760000119234_3_Domain_0 (146, 241)

LNSLDA-ELAQELGDLTDDDLHVAFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYTREWLIVNR--KNQGNSEFCSFKKTGSRRDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQTGPRR-LNVLCDVSGKGPLTTCDFDLRSLQPDERLENLLQLVSAEDF
EKEKEEARKTNRQAEIFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFRGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIADCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLASFFSVSTLERESADVEPVLGRNSVGERRSLSQSRR-PSERSLSLEENGVGS
NLKAT---TLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLRLEISP
APDVMNCCLT--PEMLPVKPFPENRTRPHK--EVLEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDPSNAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGSSGESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1712)

HL
EKFFTLCHSLESQVTFPIRVLDQKITESSLEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLP
ELHRDAPKPGGPA-VI--P-DPRYHTYGRTSAAAVSSKLMQA-RVMSSSNPDLTGA-HCA
ADEEVKTIMSSKIAD-----RNCSRMSYYGSGNNDVPGSAAAPRPVSKKHFHEELALQMV
VSTGLVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNTLPTL
ISMRLEFLRILCSHEHYLNLNLLFMNTSDTAPASPSPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVK
VKIAALYLPLVGIILDALPQLYDFT---------------DARGGKSRASGSYEEQDVAN
GINQNVALAIAGNHLNL-KMSGSM------------------------------------
----LSSL-PYKQYNMLNADTTRHLMICFLWIMKNADQGLIRRWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRR-RTP-GNDRF
PGLSENLRWRKEQTQWRQANEKMDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLM

PF06920 // ENSGT00760000119234_3_Domain_2 (1712, 2267)

RFSFGATGNFARVKMQVTMALASLVGKAP
DFNEEHLRRSLRTILAYSEEDTAMQTTPFPNQLIKI-K------------MPSL---QDG
LSPSVFRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAF
DNII---NKDHKRMFGTYFR---VGFYGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQHRRNTVLTTMHAFPYIKTRIRVIQKEEFVLTPIEVAIED
MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPNSFLH--
----------LRCGEAVEKNRRLITAEQREYQQELKKNYNKLRDSLRPMIERKIPELYKP
IFRIDSQKRDSFHRSSFRKCETQLSQGS-

----------------------------------------------------------MA
GIPASVRYT--------------RFFSFNPRYSSAEIRKQFTLPPNLGQCPRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHLNSLDL-ELTQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYTREWLIVNR--KNQGSSETCGFKKTGSRKDFHKTLQKQTF
ESETLEYAVPSAQTGPR-SLRVLCDVSGKGPITACDFDLRSLQPDQRLGHLLQHVSAEDF
ERQNEEARKTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISETFHCDLNSDQFKGFLRTHTPSVAASSQARSAVFSVTYPS
TDIYLVIKIEKVLQQGEIGDCAEPYMVIKESDGGKSKDKIEKLKLQAESFCQRLGKYRMP
FAWVPISLSSFFNVYTLEREVTDAETMVGRSSVGERRTLSQSRR-LSERALSLEENGVGH
NFKAT---PMNVNSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GSLKLEISP
APETLNCCLT--PEILPVRPFSENRSRPLK--EILEF--PTREVYVPHTVYRNLLYVYPQ
RLNFASKLASARNITIKIQFMCGEDASNALPVIFG------KSSGPEFLQEAYTAVTYHN
KSPDFYEEVKIKLPAKLTANHHLLFTFYHISCQ---QKQGASVESLLGYSWLPMLLNERL
QMGSFCLPVALEKLPPNYSMHSAEKIPLQNPPVKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPLRVLDQKISEGALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIVNSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELHRDVPKSGGLTPV---PDP-RYHTYGRTSAAVVSSKLLQA-RVMSSSNPDLAGA-HSA
ADEEVKSIMSAKIA-----DRNCNRVSYYSSGNNDVPNSTSAPRPANKKHFHEELALQMV
VSTGMVRENVFKYAWFFFELLVKSMAQYVHNTDKRDSFRRTRFSDRFKDDITTIVNVVTS
EIAALLVKPQKENDQAEKINISLAFFLYDLLSLMDRGFVFNLVRHYCNQLSAKLNNLPTL
ISMRLEFLRVLCSHEHYLNLNLFFMSA-DTAPASPCPSISSQNSSSGSSLQDQKIAGMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPDVK
VKIASLYLPLVGIILDALPQFYDFTVA-------------DARSGKSRSNGSDEEQEGGS
PINQNVALAIAGNNFN-LKASGIS------------------------------------
----LSSL-PYKQCSVLSADTTRNLMICFLWVMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMVGD-EAP-GNDRF
PGLSENLRWRKEQTHWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QATSALDCKDNLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEGEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGAVSNFARVKMQVTMSLASLVGKAQ
DFNEEHLRRSLRTILAYAEEDTAMQTTLFPTQVEEL-LYNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTATHSKLQKAF
DSII---NKGHKRMFGTYFR---VGFYGSKFGDLNGQEFVYKEPAITKLPEISHRLEGFY
GQCFGAGFVEVIKDSTPVDKAKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2270)

TYFEKSFNLRRF
MYTTPFTLEGRPRGDL--QEQYQRNTVLTTMHAFPYIKTRIRVIQKEEFVLTPIEVAIED
MKKKTLQLAVAVNQEPPDAKMLQMVLQGSVGTTVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLRENLRPMMERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQDS-

--------------------------------------------------------MATL
PTAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKQLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASNAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
EVQRDVPKSGAPTAL---PDPRSYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKIA-----DRNCSRMSYYCSGNSDAPSSTAAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFTDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLSNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTTPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTVA-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------LHLS
GSSDSRASA-------------SKVAGITGTYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMSHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQELGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPAAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQLKGFLRAHTPTVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKIT-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFT---------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNHFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVISDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRIESQKRDSFHRSSFRKCETQLSQGS-

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MFTTPFTLEGRPRGEL--SEQYRRNTVLTTLHAFPYIKTRINVIQKKEFILTPIEVAIED
MQKKTLELAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKP
VFRVSGEKRDSFHRSSFRKYETQGSQST-

------------------------------------------------------------
------------------------------------------------------------
----------------------

PF11878 // ENSGT00760000119234_3_Domain_0 (143, 241)

MTHLNSLDV-ELAQELGDFTEDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNQ--KNQGSSEICGFKKTGSRRDFHKTLQKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 647)

ESESLEGHEPSTQVRPR-HLNVLCDVSGKGPLTACGFDLRSLQPDQRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKVLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKEGDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPINLSSFFNFSTLDREVTDVESMVGKSSVGERRTLSQSRR-LSERALSLEDNGVGS
NFKPT---TIAVNNFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEISP
APEVINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PVREVYV

PF14429 // ENSGT00760000119234_3_Domain_1 (647, 840)

PHTVYRNLLYVYPQ
RLNFTNKLASARNITIKIQFMCGEDASNAMPVIF-----G-KSNGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVESLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHL
EKFFTLCHSLESQVTFPIRVLDQKISETSLEHELKLSLICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMLIAGQTANFSQFAFESVVAIANSLHNSKDLAKDQHGRNCLLASYVHYVFRLP
EPPRDPPKSGGPVAL---PDPR-YHTYGRTSAVAVSSKLMQA-RVMSSSNPDLAGT-HCA
ADEEVKNIMSSKTA-----DRNCNRMSYYCSGNNDVPSSTAAPRPASKKHFHEELALQMV
VSTGIVRETVFKYAWFFFDLLVKSMAQYVHNMDKRDNFRRTRFSDRFKDDITTIVNVVTS
ETAALLVKPQKETEQAEKMNISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPASPCPSISSQNSSSCSSFQDQKIASMFD
LTPEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAISAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLYDFTVA-------------DARSGKNRANGSDEEQEGTS
AINQNVALAIAGNNFNL-KTSGAM------------------------------------
----LSSL-PYKQYNLLNADMTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVSCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRCRAP-GNDRF
PGLSENLRWRKEQTHWRQANEKQDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLKVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGKAP
DFNEEYLRRSLRTILAYAEEDTAMQATPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQTSPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESAVSDDTLSPDEDGVCS
GRYFTESGLVGLLEHAAELFSTGGLYETVNEVYKLVVPILEAHRDFRKLTSTHDKLQKAF
DSII---SKGHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFY
GQCFGEEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRV

PF06920 // ENSGT00760000119234_3_Domain_3 (2089, 2267)

TYFEKNFNLRRF
MYTTPFTLEGRPRGDL--HEQYRRNTILTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELRKNYNKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

--------------------------------------------------------MATL
----PSAER-------------RAFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NTLDV-QLAQELGDLTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCIQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESESLECSEPDAQTGPR-HLNVLCDVSGKGPLTACDFDLRSLQPDQRLENLLQQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEEDAVE--IRPVPECPKEHLGNRILVKLLTLKFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFLNVSTLEREVTDVDPVVGRSSAGERRTLAQSRR-LSERALSLEENGVGS
NFKTS---TLSVNSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIP--GLLRLEIST
APEIINCCLT--PEMLPVRPFPENRTRPHK--EILEF--PIREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFANKLASARNITIKIQFMCGEDAGSAMPVIFG------KSSGPEFLQEVYTAITYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGGSVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISETALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRSCLLASYVYYAFRLP
EPQRDIPKSGASTAL---PDP-RYHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNIMSSKIA-----DRNCSRMSYYCSGNNDVTSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQYVHNMDKRDSVRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFTLIRHYCNQLSAKLNNLPML
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEGEGISRVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLSDFAVL-------------R--HWKSRTSGSDEEQEGAS
AINQNVALAIAGNHFNL-KTSGMM------------------------------------
----LSSL-PYKQYNMLNADTTRSLMICFLWIMKNADQSLIRKWIADLPSVQLNRILDIL
FICVFCFAYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMIRR-RA-PGNDRF
PGLNENLRWKKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVRSLNYDQSTTYLTHCYATLRALIAKFGDLLFEEEVEQ
CANLCHQVLHHCSSSMDVTRTQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLAFLVGRAP
DFNEEHLRRSLRTILAYLEEDTAMQMTPFPTQVEEL-LCNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCV
GQYFTESGLVGLLEQASELFSTGGLYETVNEVYKLVIPILEEHREFRKLTLIHSKLQRTF
DSIV---NKDHKRMFGTYFR---VGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPHKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQVPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFILRCGEAVEKNKRLITPDQREYQQELKKNYNKLKENLRPMIERKIPELYKP
IFRVESQKR--------------------

--------------------------------------------------------MATL
PSAERR-----------------AFALKINRYSSAEIRKQFTLPPNLGQYHRQSIST-SG
FPSLQLPQFYDPVEPVDFEGLLMTHL

PF11878 // ENSGT00760000119234_3_Domain_0 (147, 241)

NSLDV-QLAQDLGDFTDDDLDVVFTPKECRTLQP
SLPEEGVELDPHVRDCVQTYIREWLIVNR--KNQGSPEICGFKKTGSRKDFHKTLPKQTF

ENSGT00760000119234_3_Linker_0_1 (241, 648)

ESETLECSEPTAQAGPR-HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLEQVSAEDF
EKQNEEARRTNRQAELFALYPSVDEVGAAVSTLENLSEDSESHVDNCIFFS-FYDRFEIE
IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPS
SDIYLVVKIEKVLQQGEIGDCAEPYLVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMP
FAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRL-SERALSLEENGVGS
NFKTS---TLSVSSFFKQEGDRLSDEDLFKFLVTTKDSQ---HSYFLSL--GLLRLEIST
APETINCCLT--PEMLPVKPFPENRTRPHK--EILEF--PTREVYVP

PF14429 // ENSGT00760000119234_3_Domain_1 (648, 839)

HTVYRNLLYVYPQ
RLNFVNKLASARNITIKIQFMCGEDASSAMPVIF-----G-KSSGPEFLQEVYTAVTYHN
KSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ---QKQGASVETLLGYSWLPILLNERL
QTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDN

ENSGT00760000119234_3_Linker_1_2 (839, 1713)

HL
EKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKL
FQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLP
ELQRDVPKSGAPTAL---PDPR-YHTYGRTSAAAVSSKLLQA-RVMSSSNPDLAGT-HSA
ADEEVKNVMSSKIA-----DRNCSRMSYYCSGNSDVPSSTTAPRPASKKHFHEELALQMV
VSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTS
EIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCNQLSAKLNNLPTL
ISMRLEFLRILCSHEHYLNLNLFFMNA-DTAPTSPCPSISSQNSSSCSSFQDQKIASMFD
LTSEYRQQHFLTGLLFTELAAALDAEVEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVK
VKIAALYLPLVGIILDALPQLCDFTGV-------------D--TRRYRTSGSDEEQEGAG
AINQNVALAIAGNNFNL-KTSGIV------------------------------------
----LSSL-PYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLL
FICVLCFEYKGKQNSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRR-RAP-GNDRF
PGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENII----
--QASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQ
CFDLCHQVLHHCSSSMDVTRSQACATLYLLMR

PF06920 // ENSGT00760000119234_3_Domain_2 (1713, 2267)

FSFGATSNFARVKMQVTMSLASLVGRAP
DFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELL-CNLNSILYDTVKMREFQEDPEM
LMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDH
SYLPVGSVSF-----------------------QNISSNVLEESVVSDDTLSPDEDGVCA
GQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAF
DSIV---NKDHKRMFGTYFR---VGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFY
GQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRF
MYTTPFTLEGRPRGEL--HEQHRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIED
MKKKTLQLAVAINQEPPDPKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYSKLKENLRPMIERKIPELYKP
IFRVESQKRDSFHRSSFRKCETQLSQGS-

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PF06920 // ENSGT00760000119234_3_Domain_3 (2161, 2267)

MKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHN
KLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELRKNYNKLKDSLRPMIERKIPELYKP
IFRIDSQKRDSFHRSSFRKCETQLSQGS-