ENSGT00760000119163_3 : Linker Region Query Results

------------------MFRC--------ERAL---SLSSGSGTGDL-STHA----YLW
GKYQRGNNCGVRSFTGPLLCHFFATFKKSSPIYFLCLHSQT-GTMSRHQNQNTIQELLQN
CADCLMRAELIAQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGECLG
WMRQQRAEMELIAWGVDSGAVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEGRMTLKNLLLTDQGSTHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSIRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKSDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFNEKVMQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQDEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTDNLRRVEE
NVQQQKATGSEMSQRKQQLEIELRQVTQMRTEEGLRYKQSLDDAAKTIQDKNKEIERLKQ
LVEKETNERKCLEDENSKLQRAQYDLQKANNSATETISKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRSASDDSSKRKMLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
VEERCRRKLEDSTRETQSQLETERCRHQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GLG---GGVNDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSS-S-YSYSY---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GLG---GGVNDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSS-S-YSYSY---SFSSSSIGH----

----------------------------------------------------G----TSR
MYY--SRRCTVTDQN-------------------SDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSLHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQRLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVSLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHHSSCQDLNHNKVIETNRE
NDKQETWMLMELQKIRRQMEHCEGRMTLKNMLLADQGSTHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSDKVTQLTD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEICGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKAVEDRFD
QQKSDYDQLQKARQSEKESLGWQKMESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEEDALQQKACGSEMLQKKQHLEIELKQLIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELAKVRNSYDEEIISLKNQFET
EINITKTTIHQLTLQKEEDTSGYRAQIDGLTRENRSLSEEVKRLKSTLAQTTETLRRVEE
TAQQQKATGTEVSQRKQQLEIELRQVTQMRTEESVRYKQSLDDAAKTIQEKNKEIERLKQ
LIDTEMSARKCLEEENAKLQRAQYELQKAHSGATEMIGKLKVQEQELTRLRLDYDRVSQE
RTLKDQDIARFQSSLKDLQLQKQKVEE-----RRTASEDSAKRKKLEEELEGMRRSLKEQ
AIRITSLTQQLEQASIVKKRSEDDLRQQRDVLDGHLRDKQRTQEELRRLSSEVEALRRQL
LQEQENLKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDELRRSRSEADSDKNTTIAELRSQLQISNSRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKSRLQRLEDELTRLKTTLEAESR
LKQRLECEKQQIQTDLNQWKTQYSRKEETIRKIESEREKSEREKNSFRSEIERLQAEIKR
IEERYRRKLEDSTRETQSQLETERSRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDR
QQIYTA EKAVTGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLNDP RDSQKNFLDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQQVTVSELVDSGILRPSTVNELESGQISYDEVGERI KDFLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKEVQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAVDKGLIDRK-FFDQYRSGSLS
LTQFADMISLKNGVGSSS---------GIG--G-GISDDVFSNSRHE-SVSKISTISSVR
NITIRSSSLSDSLEESSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTSGQKLSLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGS------
--RSGSRSGSRRGSFDATGNSSYS-YS--Y---SFTSSSIGH----

------------------------------------------------------------
MYY--SRRCTVTDQN-------------------SDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISAPRVRRASSKGGGGYTCQSGSGWDEFTKRVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHID-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQRLLDQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITH-TSCQDLNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCESRMTLKNMLLADQGSTHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSDKVTQLTD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDALESMKFGDSNTVMRFLNEQKNLHNEICGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKAVEDRFD
QQKSDYDQLQKARQCEKESLGWQKMESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAK------------------------------------------------------
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-----ASNRIQESKNQCTQVVQERESLLVKIKVLEQDKSRLQRLEDELNRLKTALEAESR
LKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSFRSEIERLQAEIKR
IEERYRRKLEDSTRETQSQLETERSRLQREIDRLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDR
QQIYT AEKAITGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQQVTVSELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKEVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFRELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GIG--G-GVSDEVFSNSRHE-SVSKISTVSSVRNITIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTSGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGLELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKEVQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFRELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GIG--G-GVSDEVFSNSRHE-SVSKISTVSSVR
NITIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTSGQKLSLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRS
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

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---------------------------------------QN-GTCTVSRRQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGVQIRGNRDLEECFA--QANDQMDILDGLIRELRQMNQ
PCEMYQKRLLQLQEQMRALYKAISVPRARRASSKGGGCYSSQSGSGWDEYTKRVTSECLN
WMRQQKSEMELVKWGFDAASIEQQIS-DHRRTHNAIGDYRWHLDKVKTDLREKAAVHQLE
EEYEGLLKYSFERMDQLRQFQNLIQATSREIMWINDCEEEELLYDWSDRNTDIARKQEAF
SKRMSELELKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQATECYLKNLQDSIRKKFMCDKSMSLQCLLEQIKELENERERILEYK
RQVQSLVNKSKKIVQLKPRNPDYRSNKPIILKALCDYKQDLKTVRKGDECILKDNNERSK
WLVTGPGGVDMLVPSVSLIIPPPNPLAVDLATKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRKEDYQKIITDLEIHYQEFLRNSQGSEMFGDEDKRKMQT
QFTDAQKHYQTLIIQLPNQPRQPQPDDIYTTNFTVIPTETCSVGSS---NTIIVNERNRE
HDKQEAWLLMELQKLRRQIESSEIRMVQRAPLGVDQGALHDFSVRIQELE-GVQNDSQIM
A--ETLNKHKDLLPNFRGCEKYVYLQSEINALFQKLENINGVSAGYLDSLNVLRCLLQLI
LQTEDVIRVFEVRLSEEETVPLDLDKVEAYRACLKKMKADLNMKKSLLNALENELQKMLQ
IHSQSCQSYTLYDMDIGKFSDKVTQLID---RWQRAEKQIDNRSWDLERQIKQLKTYRD-
LYQALCKWICDAKRRQDSIESMKLCDSNTIMRYLHDQKNLHSEICGKRDKVEELLKHADQ
CSAAIKDYELQVASYSSGLETLLNIPIKKCVVQSPAVLILQEASEAQARYIELLTRSGDY
YKFLSEMLKSMEDLKMKATKIELLEEELRLARDSNSETNNKHKFLEQNLQKYQMDISQLK
AKLMSLEEMKRQAEMDGNSAKQNLDKCYAQIKDLNDRITRLTYETEDEKRKRKLLEDRYE
QQKNDYDQLQKTRQNEKDSLGWQKLESEKVIKEKEYEIERLRVLLQD-----EGTRKREY
ENELAKVRNQFSEEMSNLKNKYETEINIKKTTIQQIAAQKDDDAKGLRAQVDRLTRENRD
LKDEIVRLNDAILQTTDQRRRAEEDALQHKACSSEVSQQKHQLELELKQIIQLRGEDNSR
YKQALEEAASTIQDKTKELERLKVQLQEEAKSRWELENELAKVRNSYDEEIISLKNKYET
EINITKTTIHQVTMQKEEDTNNYRTQLDNAMRENRNLCEEIRRLKNTISQTTDNLRKIEE
NAQQQKAAGSELSQKKQQLEIELKQVIQRHSDESMRYKQSLDDASKTIKERNKEIERLRK
LLDVETSQRKELEDENSQLKRVQFDLQKANTSATETINKLRIQEQELARLKIDYERVSQE
KKGRDQESAKFQSTVKDLQIQKHKLEEELCRQNKSVMEETARRKKLEEEIESMRRSLREQ
SVKITNLTQQIEEVSIVKKRNEDDLRHQREVLDGHVREKQRYMEEIRKYTSDIETLRRQL
VQEQEQLKQAHLRYEHLQKTSEEKSKNLNECKIEIERLQSLTENLTKEHLLLEEELRNVR
LEYDDLRMVRSEVD-EKNTTIAELKNQLQTSSKQTLELQGLINDLQKEREKLRQEIEKFQ
KQALEASNRIQESKNQYSHIMQERETLLIKMSALEQDKARLQRLEEELNRLKVSLESESR
LKQRLESEKQQILNDLNQWKSQHSRTEESIRKIQCEREKSEREKNTLRTEIERLQMEIKR
IEERYRCRLEETAVKNQSELESERLRLQREIEKLKQRPYGSHRSTQTEEDFCIDASKLLF
SGLRKKITAMQLYECQIIDKVTLDKLLKGQRSVEEV-AADIEPYLKGAGAIAG---VSVL
PRQKYSFVEA-KRNQLLTAENAVLLLEAQAATGGVIDPHRNEVLTVDSAIARDLIDFDDR
EQIYTA EKAITGFKDPFSGKTVPVSEAIKKNLIDRETG IRLLEAQLAVGGIVDPVNSVFL
PKDIALSRGLIDKDLYRILNNC QSATKNFIDPTTKKAVTYMQLKEKCRIEPHTGLLLLPV
QKRSMSFQGIRQPVSADALLEAGIIKESTRNDLERGAITVEEVSERI IDFLQGSSCIAGI
YNEATKEKLGIYQAMKIGLVRPGTALELLEA Q AATGFIVDPVSNVRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYKDPETGNIISLFQAMNKELIERGHG IRLLEAQIATGGIIDPKES
YRLPVETAYKRGYFNEELNQILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEATGLCL
LPLREKKKVVHTSQ KNTLRKRRVVIVDPETNREMSVQEAYSKGLIDYDTYTELAEQ----
-----ECEWEEITITGSDGSSRVVLVDRKTGSQYDIQDAIDKGLVERK-FFDQYRSGSLS
LTQFADMISCRNGTDEVFRH-----------------------ESVTRSPTVLSVRSSSS
MIR--SGSFSETTEECSPIAAIFDTENLEKISISEAIQRGIVDSITG QRLLEAQACTGGI
ICPTTGQRLSLQEATSQGIVDQDMATRLKPA QKAFLGFEGIKGGRKRMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVRGRISTEEAIRNGLIDGRAAQKLQDTNSYPKILTCPKT
KLKISYKDAMNRSMVEDITGLKLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------
GSRSGSRSGSRRGSFDASATSSYS-YSYST----FSSGSIGR----

--MSCNGGSHPRINTLGRMIRAESGPDLRYEVTS------GGGGTSRMYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDECF--AQANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRGIHNSIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGYPQHQ----------TVTTTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFGEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWVYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGTRKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSSSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLIHDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTDCEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIAAGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGTTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGTTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRLTRAESGPDLRYEVTS---GGGGGGGTSRMYYS---------
------RRG-------------------VITDQNPDGYCQT-GTMSRHQNQNTIQELLQN
CSDSLMRAELIVQPELKY--GDGIQLTRSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRVEMDMVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIIQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPHHQ----------TVTTTEITHHGTCQDVNHNKVIETNRE
NDKQETCMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFADSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDSLTQENRSLSEEVKRLKNTLAQTTENLRRVEE
DVQQHKATGSEVSQRKQQLEVELRQVTQMRTEESIRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSVMETTNKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRSASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTHVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRRKLISAESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKLSTISNVRNLTIRSSSFSDSLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTNSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKLSTISNVR
NLTIRSSSFSDSLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTNSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC------GGGTTSRMYYS---------
------RR--------------------CTVDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLSRSRELDEYFA--QANDHMEIADSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTRRVTSDCLG
WMKQQRAQMDMVAWGVDLTSVEQHIN-SHRGIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSELEVKEKELNKLKQECDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQATEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQ------------TVTTTEITHLGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQMEHCEGRMSLKNLLLTDQGSSHHITVKINELK-SVQNDSQGI
A--AVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLRKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNDQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLSIPIKRTMVQSPSGVILQEAAEIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKSDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYEKEINITKTTIKEISMQKEDDSKNLRNQLDKLCRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEMMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEARRRWEYENELSKVRNSYDEEIISLKNQFET
EVNITKTTIHQLTMQKDEDTSNYRAQIDSLTRENRSLSEEIERLKNTLTQTTENLRRVEE
NVQQQKATGSEVSQRKQQLEIELRQVTQMRTEESARYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENAKLQRAQYDLQKANSSATETINKLKGQEQELTRLRIDYERVSQE
RTVRDQDITRFQGSLKELQVQKQKVEEELNRLKRTASEDSSKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLEGHLREKQRTQEELRRLSAEVEALSRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDELRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKTQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
AKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIETEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERCRLQREIEKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGVIDPHRNEKLTVDSAIARDLIDFDDR
QQIYT AEKAITGFDDPFTGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFVDPVTKKKVSYMQLKERCRIEPHTGLLLLTV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YDETTRRKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDDETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFEQYRSGSLSLTQFADMISLKNGVGSSG------------GLSGSVSDDVFSSSRHD-SVSKVTTISSMRNLTIRSSSLSDPLEECTPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLLLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEGQGRISMEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAVNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGLELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDDETGLCL
LPLKEKKKQVQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFEQYRSGSLS
LTQFADMISLKNGVGSSG------------GLSGSVSDDVFSSSRHD-SVSKVTTISSMR
NLTIRSSSLSDPLEECTPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLLLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEGQGRISMEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAVNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRLNTLGRMTRAESGPDLRYEVTG---GGGG----------------TSR
MYY---RRCIVADQN-------------------SDGYCQT-GTISRHQNQNTIQDLLQS
CSDCLMRAELIVQPELKY--GDGIQLSRSRELDECFA--QANENMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLGSVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKIKNDLNLKKSLLATMKTELQKAQQ
VHSQTSQQYPLYDLDLGKFSEKVTLLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLCDAKRRQDSLESMKFGDSNTVMRFLNEQKXXXXXXXXXXXXXXXXXXXXXX
XXXXXXDYELQLASYTSGLETLLSIPIKRTMVQSPSGVILQEAGDIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEID-EKRRRKVVEDRFD
QQKNDYDQLQKARQCE-ESLGWQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXSNLRNKYETEINITKTTIKEISLQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEELALQQKACGSETLQKKQQLELELKQLTQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKVEFQEEAKRRWEYENELAKVRNNYDEEIISLKNQFET
EISITKTTIHQLTMQKDEDTSGYRAQIDTLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
NVQQHKATGSEMSQRKQQLEIELRQINQMRTEESTRYKQSLDDAAKTIQDKNKEIERLKQ
LIETETKERKCLEDENAKLQRTQYELQKAHSSATETISKLKGQEQELTRLRIDYERVSQE
RMVKDQDITRIQSSLKELQVQKQKAEEELNRLRRAATEDSSKRKKLEEELEGMRRSLKEQ
AIKVTSLTQQLEQMSIIKKRSEDDLRQQRDVLEGHVREKQRTQEELRRLSSELEALRRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGQSEADSDRNATISELQSQLQISNNRTLELQGLINDLQRERGNLRQEIEKFQ
KQALEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXKQQIQNDLNQWKTQYSRKE-EIRKIESEREKSEREKNNLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERCRLQREIDRLRQRPYGSHRETQTEYEWTVDTSTLVF
DGLRKKVTAMQLFECQLIDKTTLDKLMKGKKSVEEV-ASEIQPYLRGAGAIAG---ASAS
PKDKYSLVEA-KRKKLITPEATVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDR
QQIYTA EKAITGFDDPFSGKTVSISEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLNDP RDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVSELVDSGILRPSTVNELESGQISYDEVGERI KDFLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFRELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQEAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSSTM-----------VSSSTSDDVFSSSRHE-SLSKVSTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLVDQDMATRLKPA QKAFVGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMS-------------------------------------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLGRSRELDECFA--QANDQMDITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISAPRVRKASSKGGGGYTCQSGSGWDEYTKRLTSECLG
WMRQQKAEMDMVTWGVDAASVEQHIS-SHRSVHNAIGDYRWQLDKIKADLREKAAIYQLE
EEYENLLKSSFERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SVRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENSAYFQFFEEAQSTEAYLKGLQDSIRKKYTCDKNMSLQRLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLEVHYQEFIRNSQGSEMFGDDDKRKIQT
QFTDAQKHYQTLVIQLPGHHQHQ----------TVTTTEITHLGSCKDTNHNQIIETNRE
NDKQETWMLLELQKIRRQMEHCEGRMTLKNPLIPDQGTSHHITVKINELK-GVQNDSQAI
A--EFLNQLKDMLANFRGSEKYCYLQTEVFGLFQKLENINGVTDGYLNSLFSVRGLLQAI
LQTEDMLKVYESRLTEEETVCLDLDKVEAYRCGLKKMKTDLNLKKSLLATMKTELQKALQ
IDAQTSQQYPLYDLDLGKFTEKVTQLSD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWIYDAKRRQDAIESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKVAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAAEIHARYIELLTRSGDY
YRFLSEILKSMEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQVECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKDLNDKITRLTYEIEDEKRKRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKTIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNQYNEEMSNLRNKYETEINITKTTIKEISMQKEDDAKSLRIQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENAMQQKACGSEIMQKKQQLEIELKQVIQQRSEDNMR
HKQSLEEAAKTIQDKNKEIERLKIEFQEEAKRRWDYENELAKVRNCYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTCGYRAQLDNLTRENRSLSEEVKRLKNTLAQATENLRRVEE
TAQQQKASGSEISQKKVQLEIELKQVTQMRSEESMRYKQSLDDAAKTIQDKNKELERLKK
LIETETSQRKALEDENAKLQRAQFDLQKANSSVTETITKLRIQEQEMARLKIDYERLSQE
RVGKDQDIAKFQTSLKDLQFQKQKVEEELNRLKKTASDESSRRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQHRDVLDGHVREKQRTQEELRKLAAEVEVLRRQL
LQEQENVKQAHLRNEHFQKVIEDKSKSLNESKIEIERLQSLTENLTKEHLILEEELRNLR
LEYDDLRRGRHEADNDKNVTISELRSQLQTSNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKMRLQRLEDELNRAKATLESESR
LKQRLECEKQQIQNDLNQWKSQYSRKEEAIRKIESEREKSEREKNCLRSEIERLQAEIKR
IEDRCRRKMEDSSRETQSQMDAERCRLQREIEKLKQRPYGSHRETQTEDEWAIDPSKLMF
DGLRKKVTAMQLYECQLIDKATLDKLLKGKKSVEEV-ASDIEPFLRGAGAIAG---ASAS
PKDKYSLVEA-KRKKLISPESTVMLLEAQAATGGVIDPHRNERLTVDNAIARDLIDFDDR
QQIYT AEKAITGFNDPFSGKTVPVSEAIKKNLIDKETG LRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFIDPVTKKKVSYMQLRERCRIEPHTGLLLLTV
QKRSMSFQGIRQPVTVTELVNSGILRPSTVNELESGQISFDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVGNQRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYKDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVEMAYKRGYFNEELNEILLDPSDDTKGFFDPNTEENLTYLQLKERCMKDELTGLCLLPLKEKKKQFQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFVELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGNQYDIQEAIDKGLVDRK-FFEQYRSGSLSLTQFADMISIKNGGGV---------------GVGGAGDEVFSSSRHE-SVSKSSSISGIRNLTIRSTSLSDPLEELSPIAAIFDTENLEKISISEGIQRGIVDSITGQRLLEAQACTGGIISPTTGQKLPLQDAVSQGLVDQDMATRLKPAQKAFVGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLIDPEMNGRISTEEAIRKGLIDGRAAQKLHDTGNYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGS--------RSGSRSGSRRGSFDASGSSSYCYSYSSF-----SSSSIGLELLEAQAATGFIVDPVGNQRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYKDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVEMAYKRGYFNEELNEILLDP SDDTKGFFDPNTEENLTYLQLKERCMKDELTGLCL
LPLKEKKKQFQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFVELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGNQYDIQEAIDKGLVDRK-FFEQYRSGSLS
LTQFADMISIKNGGGV---------------GVGGAGDEVFSSSRHE-SVSKSSSISGIR
NLTIRSTSLSDPLEELSPIAAIFDTENLEKISISEGIQRGIVDSITG QRLLEAQACTGGI
ISPTTGQKLPLQDAVSQGLVDQDMATRLKPA QKAFVGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLIDPEMNGRISTEEAIRKGLIDGRAAQKLHDTGNYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGS------
--RSGSRSGSRRGSFDASGSSSYCYSYSSF-----SSSSIGH----

--MSCNGGSHPRINTLGRLTRAESGPDLRYEMTS---GCGGGGGTSRMYYS---------
------RRG-------------------VITDQNPDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDEYFT--QANDQMEIIDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMMAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEREREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPHHQ----------TVTTTEITHLGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMSLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKSLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDSLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
DVQQHKATGSEASQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSVMETTNKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELTRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQVEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEEKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATIAELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLISAESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAVKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIESHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SLGSGVSDDVFSSSRHE-SVSKLSTISNVRNLTIRSSSFSDSLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDINSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SLGSGVSDDVFSSSRHE-SVSKLSTISNVR
NLTIRSSSFSDSLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDINSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRLNTLGRMTRAESGPDLRDLRDL---RCDA---TC----GGG----TSR
TYY--SRRCA-------------------VNDQNSDGYGQT-GTMSRLQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRHMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSLHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKSSFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SVRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIIQLKPRNPDYRSSKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNHNKMIETTRE
NDKQETWLLMELQKVRRQVEHCEGRMTLKNLLLADQPSTHHITVKINELK-SVQNDSQTI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKAELHKAQQ
IHSQTSQQYPLYDLDLGKFSDKVTQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQNFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLSSLEELKRQAELDGKSAKQNLDKCYTQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQSEKESLGWQKLESEKAIKEKEYEIERLKVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKSLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNTR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNSYDEEIISLRNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEIKRLKNTLAQTTENLKRVEE
NIQLHKATGSEMSQRKQQLEIELRQVTQMRTEESVRYKQSLDDAAKTIQDKNREIERLKQ
LVEKETSERKCLEDENARLERVQYDLQKANSSATDTISKFKGQEQELTRLRIDYERISQE
RTVKDQDIARFQSSLKELQLQKQKVEEELSRLKRTACEDSSKRKKLEEELEGMRRSLKEQ
SIKITSLTQQLEQASIVKKKSEDDLRQQRDVLEGHLRDKQRTQEDLRRLSSEVEALRRQL
LQEQDNVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEEDHDKNAAICELRNQLQMSNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIHESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEEELSRLKTTLETEGR
VKQRLESEKQQIQNDLNQWKTQFSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLENERCRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPFTKKKVSYMQLRDRCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFDQYRSGSLSLTQFADMISLKNGVGGSI------------SMGGSVNDDVFSSSRHE-SVSKISTISSIRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEAIDRGIVDSITGQRLLEAQACTGGIIHPTTGQKLLLQDAVAQGLVDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFDQYRSGSLS
LTQFADMISLKNGVGGSI------------SMGGSVNDDVFSSSRHE-SVSKISTISSIR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEAIDRGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLLLQDAVAQGLVDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTS------GGGGTSRIYYS---------
------RRG-------------------VITDHNSDGYCQT-GTMSRHQNQNTIQELLQS
CSDCLMRAELIVQPVSFL--CSHR-------FSQSLGHTQENDY-------------IEI
TVSFFLFRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADL----------
-------KASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSATESINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSCEVEALRRQL
LQEQDSVKQGHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTC---GGGGGGGGG-GGGGGG----TTR
MYY--SRRCTANDQN-------------------SDGYWWV-PGRRRGAP----------
-------GPGCASPELKY--GDGIQLARSRELDEYFA--QANDHMEIADSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRVTSECLG
WMRQQRAEMDVVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFDRMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSSKPIILRALCDYKQDQKIVHKGDECILKDNTERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYLKTIQDLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHLGTCQDVNHNKVIETNRE
NDKQETWMLIELQKIRRQMEHCEGRMSLKNLLLADQGSTHHITLKINELK-SVQNDSQGI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVYLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLHDAKRRQDSLESMKFGDSNTVMRFLNDQKNLHNEICGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRAMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDKLCRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEMMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELGKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIERLKNTLAQTTENLRRVEE
NVQQQKAAGSEVSQRKQQLEIELRQVTQIRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENAKLQRAQYDLQKANSSATETITKLKGQEQELTRLRIDYERVCQE
RTVKDQDITRFQNSLKELQLQKQKVEEELTWLKRTASDDSSKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLEGHLREKQRTQEDLRRLSSEVEALRRQL
LQEQDNVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKTQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKAALEAESR
AKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESDREKSEREKNGLRSEIERLQAEIKR
IEERCRRKLEDSTRDTQSQLETERCRLQREIDKLRQRPFGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYMQLKERCRIEPHTGLLLLTV
QKRSMSFQGIRQPVTVTELVDSGILRQSTVHELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIERK-FFDQYRSGSLSLTQFADMISLKNGVGSSG---------SMG--G-SVSDDVFSSSRHD-SVSKISTISSIRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLLLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-K-KMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYRDAINRCMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRPGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYDTFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIERK-FFDQYRSGSLS
LTQFADMISLKNGVGSSG---------SMG--G-SVSDDVFSSSRHD-SVSKISTISSIR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLLLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-K-KMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYRDAINRCMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRPGSRSGSRS
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

---------------------PVSAPPSR-------------GR--HA-WGGQ----VAR
---------------------TRPARRYSGLGGNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSLHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTESYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQSLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHLGSCQDANHNKVIETNRE
CDKQETWLLMELQKIRRQMEHCEGRMSLKNLLLTDQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVSDGYLNSLCAVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLSD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQSFCKWLHDAKRRQDSLESMKFCDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKVAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAAEIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYAQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEENVLQQKACGSEIMQKKQQLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKADFQEEAKRRREYENELGKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLAQTTENLRRVEE
NVQQQKATGSEMSQRKQQLEMELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LIEKETNERKCLEDENVKLQRVQYDLQKANSSATETISRLKVQEQELTRLRIDYERVSQE
RTLKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASEDSSKRKKLEEELEGMRRSLKEQ
VIKITNLTQQLEQASIVKKRSEDDLRQQRDVLEGHLREKQRTQEELRRLSSEVETLRRQL
LQEQENVKQAHVRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDELRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRLKSSLEAESR
VKQRLESEKQQIQNDLNQWKTQYSRKEEAIRKIEAEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERCRLQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKATLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLTV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGIGNGS---------GVC---TSVNDDVFSSSRHE-SVSKISTISSVRNLTIRSSSFSDSLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---TFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGIGNGS---------GVC---TSVNDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSFSDSLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---TFSSSSIGH----

--------------PLSKIYRAKKIPL-----FA---HFWGGNGESFYVWL---------
------L--------------------------CVCLLSQS-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDHMEVVDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRGDMDMMVWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDQLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHLGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQMEHCEGRMSIKNLLLADQGSTHHITLKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCAVRALLQAL
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKVKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNDQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLSSLEELRRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKSLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
NVQQQKATGSEVSQRKQQLEIELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIDRLKQ
LIDKEANERKCLEDENVKLQRAHYELQKANSSATETISKLRTQEHELTRLKIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSDVEALRRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEVDSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLDAECR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IDERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAVTGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFIDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVNSGILRQSTVHELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILTDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGGGS------------SIGGSVSDDVFSSSRQE-SVSRISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAASQGLIDQDMATRLKPAQKAFIGFEGVKG-K-KMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRGAQRLQDLGSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRTGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEI LTDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGGGS------------SIGGSVSDDVFSSSRQE-SVSRISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAASQGLIDQDMATR LKPAQKAFIGFEGVKG-K-KMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRGAQRLQDLGSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRTGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTS------GGGGTSRIYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGMQLTRSRDLDECF--AQANDQMEILDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKA-----------------------------------------------------
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------SNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYELTC---GSGGGGGGGGGG-----------
-------GG-------------------GIWFLCVCSISQM-GTMSRHQNQNTIQEYLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCEAYQKRLLQLQEQMRALYKAISAPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVTWGVDLASVEQHIN-SHRAIHNAIGDYRWQLDKVKADLREKAAIYQLE
EEYENLLKASFERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQRLLDQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVRKGDECILKDNNERSK
WYVTGPGGVDMLVPSVSLIIPPPNPLAVGLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTISDLEFHYQEFIKNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHVGTCQDVNHNKVIETNRE
NDKQEAWLLIELQKVRRQIELCEGRMTLKNILLADQGSAHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCAVRALLQAL
LQTEDMLKVYEARLTEEETVSLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSDKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEICGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKTAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTMEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEENALQQKASGSEMLQKKQQLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFKEEAKRRCEYENELAKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRNLSEEIKRLKNTLAQTTENLRRVEE
NMQQQKATGTEMSQRKQQLEIELRQVTQMRSEESQRYKQSLDDAAKTIQDKNKEIERLKQ
LIETETNERKSLEDENTRLQRAQYDLQKANSTAAETISKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEDELNRLKRVASEDSAKRKKLEDELEGMRRSLKEQ
AIKVTSLTQQLEQVSIVKKRSEDDLRQQRDLLESQVREKQKTQEELRRLSLELEALRRQL
FQEQENVKQAHLRNEHFQKGIEDKSRSLNESKIEIERLQSLTESLTKEHLMLEEELRNLR
LEYDDLRRSRNEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQDRESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSLKEETIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERSRLQREIDKLRQRPYGSHRETQTEHEWTVDTSKLVF
EGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKDKYSLVEA-KRKKLITPESTVMLLEAQAALVGSL-PHRNEKLTVDIAIARDLIDFDDR
QQIYTA EKALTGFDDPFSGKTVSVSEAIKKNLIDRETG IRLLEAQLASGGIVDPVNSVFL
PKDVALARGLIDKDLYRSLNDP RDSQKNFVDPVTKKKVSYMYLRERCRIEPHTGLLLLTV
QKRSMSFQGIRQPVTITELVNSGILRPSTVNELESGQISYDEVGERI KDFLQGSSCIAGI
YNEATKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELNEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEATGLCL
LPLKEKKKQVQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQEAIEKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS------------GLGGSISDDVFSSSRHD-SVSKISTISSIR
NLTIRSSSLSDPLEESTPIAAIFDTENLEKISISEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATRLKPA QKAYIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAISRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

----------------GRMARADSGTDLRYEMSSHVVGGGGGGT-----------HTHKT
YYYQKT----------------------YGGDYASDGYGQN-GTCTVTRRQNTIQELLQN
CSDCLMRAELIVQPPNPLYLGMGYSLSLSQMVQHYFQ--MTMNPLVIGLQLIKSVNQRPR
SWNLLFLKLLQLQEQMRALYKAISVPRARRASSKGGGCYSSQSGSGWDEYTKRVTSECLN
WMRQQKAEMELVKWGFDAASIEQQIS-DHRRTHNAIGDYRWHLDKVKTDLREKAAVHQLE
EEYEGLLKYSFERMDQLRQFQNLIQATSREIMWINDCEEEELLYDWSDRNTDISRKQEAF
SKRMSELELKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQATESYLKNLQDSIRKKFICDKSMSLQSLLEQIKELENERERILEYK
RQVQSLVNKSRKIVQLKPRNPDYRSNKPIILKALCDYKQDLKTVRKGDECILKDNNERSK
WLVTGPGGVDMLVPSVSLIIPPPNPLAVDLATKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRKEDYQKIITDLEIHYQEFLRNSQGSEMFGDEDKRKIQT
QFTDAQKHYQTLIIQLPNQPRQPQ---------TVIPTESCPVGTS---NTIIVNERNRE
HDKQEAWLLMELQKLRRQIEASEIRMVQRAPLGVDQGALHDFSVRIQDLE-GVQNDSQIM
A--ETLNKHKDLLPNFRGCEKYVYLQSEINALFQKLENINGVSAGYLDSLNALRCLLQLI
LQTEDVIRVFEVRLSEEETVPLDLDKVEAYRACLKKMKSDLNMKKSLLNTLENELQKMLQ
IHSQSCQSYTLYDMDVGKFSDKVTQLID---RWQRAEKQIDNRSWDLERQIKQLKTYRD-
LYQALCKWICDAKRRQDSIESTKLCDSNTIMRYLHDQKNLHSEICGKRDKVEELLKHADQ
CSAAIKDYELQVASYSSGLETLLNIPIKKCVVQSPAVLILQEASEAQARYIELLTRSGDY
YKFLSEMLKSMEDLKMKATKIELLEEELRLARDSNSETNNKHKFLEQNLQKYQMDISQLK
AKLMSLEEMKRQAEMDGNSAKQNLDKCYAQIKDLNDRITRLTYETEDEKRKRKLLEDRYE
QQKNDYDQLQKTRQNEKDSLGWQKLESEKVIKEKEYEIERLRVLLQD-----EGTRKREY
ENELAKVRNQFSEEMSNLKNKYETEINIKKTTIQQIAAQKDDDAKGLRAQVDRLSRENRD
LKDEIVRLNDAILQTTDQRRRAEEDALQQKACSSEVSQQKHQLELELKQIIQLRGEDNSR
YKQALEEAAATIQDKTKELERLKLQLQEEAKSRWELENELAKVRNSYDEEIISLKNKYET
EINITKTTIHQVTMQKEEDTNNYRTQLDNAMRENRNLCEEIRRLKNTITQTTDNLRKIEE
NAQQQKAAGSELSQKKQQLEIELKQVIQRHSDESMRYKQSLDDASKTIKERNKEIERLRK
LLDVETSQRKELEDENNQLKRVQFDLQKANTSATETINKLRIQEQDLARLKIDYERVLQE
KKGRDQESAKFQSTVKDLQIQKHKLEEELCRQNKNVMEETARRKKLEEEVEGMRRSLREQ
SVKITNLTQQIEEVSIVKKRNEDDLRHQREVLDGHVREKQRYMEEIRKYTSDIETLRRQL
VQEQEQLKQAHLRNEHLQKTSEEKSKNLNECKIEIERLQSLTENLTKEHLLLEEELRNVR
LEYDDLRMVRSEVD-EKNSAIAELKNQLQTSNKQTLELQGLINDLQKEREKLRQEIEKFQ
KQALEASNRIQESKNQYNHIMQERETLLIKMSALEQDKARLQRLEEELNRLKVNLESESR
LKQRLENEKQQILNDLNQWKSQHSRTEESIRKIQCEREKSEREKNTLRSEIERLQMEIKR
IEERYRCRLEETAVKNQSELESERLRLQREIEKLKQRPYGSHRSTQTEEDFCIDASKLVF
NGLRKKITAMQLYECQLIDKLTLDKLLKGQRSVEEV-TADIEPFLKGAGAIAG---VSVL
PRQKYSFVEA-KRNQLLTAENAVLLLEAQAATGGVIDPHRNEVLTVDSAIARDLIDFDDR
EQIYTA EKAVTGFKDPFSGKTVPLSEAMKKNLIDRETG MRLLEAQLAVGGIVDPVNSVFL
PKDVALSRGLIDKDLYRILNNC QSTTKNFIDPSTKKAVTYVQLKEKCRIEPHTGLLLLPV
QKRSMSFQGIRQPVSADALLEAGIIKESTRNDLERGAITVEEVSERI INFLQGSSCIAGI
YNEATKEKLGIYQAMKIGLVRPGTALELLEA Q AATGFIVDPVSNARLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYKDPETGNIISLFQAMNKELIERGHG IRLLEAQIATGGIIDPKES
YRLPVETAYKRGYFNEELNQILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDDATGLCL
LPLREKKKVVHTSQ KNTLRKRRVVIVDPETNREMSVQEAYSKGLIDFDTYTELAEQ----
-----ECEWEEITITGSDGSSRVVLVDRKTGSQYDIQDAIDKGLVEKK-FFDQYRSGSLS
LTQFADMISCRNGTDEVFRH-----------------------ESVTRSPTVLSVRSSSS
LIR--SGSFSETPDECSPIAAIFDTENLEKISISEAIQRGIVDSITG QRLLEAQACTGGI
ICPTTGQRLSLQEATSQGIIDQDMATRLKPA QKAFIGFEGIKSGRKRMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVRGRISIEEAIRNSLIDGRAAQKLQDTNSYPKILTCPKT
KLKISYKDAMNRSMVEDITGLKLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------
GSRSGSRSGSRRGSFDASATSSYS-YSYST----FSSGSIGR----

-------------------------------------------------MP---------
------R-S-------------------GVHDFRDVTRSQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGMQLTRSRDLDECF--AQANDQMEILDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKA-----------------------------------------------------
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------SNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHSRINTLGRMTRAESGPDLRYEMTYGGGGGGGGGGGGGGGGGGGSN---NR
MCY--MRRC-------------------TVNDQNSDGYCQTGGTMSRHQNQNTIQELLQN
CADCLMRAELIVQPELRY--GDGVQLSRSRELDECFA--QANDQMEITDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISGPRVRKASSRGGGGYTCQSGSGWDEYTKRLTSECLG
WMRQQRAEMDLVIWGVDSASVEQHIN-SHRVVHNVIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASLERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYTCDKNMSLQRLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIIQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHHQHQ----------TVTEVTHVGSCKEPIQNQNQVIEINRE
NDKQETWILLELQKVRRQIEHCENRMTIKNILQADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEIYGLFQKLENINGVTDGYLNSLCSVRGLLQAI
LQTEDTLKVYESRLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLCDLDLGKFSDKVSQLSD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWIYDAKRRQDSLESMKFGDSCTVMKFLNEQKALHNEISGKRDKSEEVQKIAEL
CAHSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAAEIHARYIELLTRSGDY
YRFLSEMLKSLDDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFR
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRKRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQRLESEKTIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDTKGLKNQVDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEENAIQQKACGSELMQKKQQLEIELKQVIQQRSEDNTR
HKQSLEEAAKTIQDKNKEIERLKTEYQEEAKRRWDYENELGKVRNNYDEEIISLKNQFET
EINITKTTIHQLTKQKEEDTSGYRTQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
NVQQQKATGSEMSQRKQQLEFELKQVTQMRSEESMRYKQSLDDAAKTIQDKNKELERLKK
LIETETNQRKCLEEENSKLQRTQYDLQKANSNATETISKLKIHEQELTRLRIDYERISQE
RTIKDQDISRFQSSLKDLQFQKQKVEDELNRLKKTASDECSKRKKLEDELESMRRSLKEQ
AIKITNLTQQLEQASITKKRSEDDLRQQRDVLDGHVREKQRTQEELRKLASEVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGKSEADCDKNATISDLRSQLQISTNRTLELQGLINDLQRERENLRQEIEKFQ
KQAIEASNRIHESKNQCSQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLESEIR
VKQRLENEKQQIQNDLNQWKSQYSRKEEAMRKFESEREKSEREKNCLRSEIERLQAEIKR
IEDRCRRKLEDSTRETQSQMESERCRMQREIDRLKQRPYGSHRETQTEEEWSVDPSKLIF
DGLRKKVTAMQLYECQLIDKSTLDKLLRGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGVIDPHRNEKLTVDNAIARDLIDFDDR
QQIYT AEKAVTGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVIDPINSVFL
PKDVALSRGLIDRDLYRSLND PRDSQKNFVDPINKKKVSYVQLRERCRIEPHTGLLLLLV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAHKRGLVGIEFKEKLLSAERAVTGYKDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELNEILSDPSDDTKGFFDPNTEENLTYLQLKERCMKDEETGLCLLPLKEKKKPIQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFVELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGFVDRK-FFDQYRSGSLSLTQFADMISLKNGGSS-------------VGS-GSGGDDVFSSTRHD-SITKTSSISSIRNLTIRSSSLSDPLEETSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIINPTTGQRLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISSEEAIRKGLIDGRGAQRLHDTSNYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAALVSSKGLPSPYNVSSAPGSRSGSRSGS--------RSGSRSGSRRGSFDASGNSSYSSYSYTF-----SSSSIGLELLEAQAATGFIVDPVSNLRLPVEEAHKRGLVGI
EFKEKLLSA ERAVTGYKDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELNEILSDP SDDTKGFFDPNTEENLTYLQLKERCMKDEETGLCL
LPLKEKKKPIQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFVELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGFVDRK-FFDQYRSGSLS
LTQFADMISLKNGGSS-------------VGS-GSGGDDVFSSTRHD-SITKTSSISSIR
NLTIRSSSLSDPLEETSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
INPTTGQRLSLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISSEEAIRKGLIDGRGAQRLHDTSNYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAALVSSKGLPSPYNVSSAPGSRSGSRSGS------
--RSGSRSGSRRGSFDASGNSSYSSYSYTF-----SSSSIGH----

------------------------------------------------------------
---------------------------------------QT-GTMSR-QNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLAQSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDVYQKRLLQLQEQMRALYKAISVPRGRRASSKGGGGYTCQSGSGWDEVTKRLTSECLG
WMRQQRAEMDMITWGVDLASVEQHIS-SHRTIHNAIGDYRWQLDKIKADLXXXXXXXXXX
XXXXXXXKISFERMDHLRQLQNIIQATSQEIMWINDCEEEELLYDWSDRNTDIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLSQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSVRKKYLCDKNMPLQRLLEQIKVLEQEWEKILENK
RQVQNLVNKSKRIVQLKPRNPDYKSNKPIIVRALCDYKQDQKIVHKGDECILKDNNERSK
WHVTGPGGVDMLVPSVGLIIPPPNTLAVDLSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIKTM-TIAKLKTMRQEDYLKTISDLELRYQDFIRDSQGSEMFGDDDKRKIQT
QFTDAQKHYQTLVIQLPGYPQQQ----------TVTTTEITHLGSCQAVNHNKVTETNRE
NDKQEMCLLMELQKIRRQMELCESKMTLKNILLADQRSSHHITVKISELK-GLQNDSQAI
A--QVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCVVRALLQAI
LQTEDMLKVYEAKLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKQSLLATMKTELQKAQQ
IYCQTSQQYPMYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWNLEKQIKQLRNYRD-
NYQTFCKWLCDAKRCQDNLESMKFGDSSMVMRFLNEQKNLHSDISSKRDKSEEVQKLAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTIVQSPSGMILQEAAEMHARYIELLTRSADY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCSKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYSQIKELNEKITRLTYEIEHEKRSRKTVEDRFD
QQKNEYDQLQKARQSERESLGWQKIESEKAIKEKEFEIERLRVLLQE-----EGTRKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNFQNKLDRCMKENRD
LKAEIVRLTDSILQTTEQRRRAEEDALQQKACGSEMLQKKQHLEMELKQVIQQRSEDSAR
HKQSLEEAAKTIQDKNKEIERLKAEFQQEAKHRREYENELAKVRSNYDEEIISLKNQFET
EINITKTTIHQLTLKKEEDTSGYRAQIDNLTRENRSLSEEVTKLKNALAQTTENLRRVEE
NVQQQKAAGLEMSQRKQQLEVELKQVTQVRMEESXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKR---VSEDCRKKLEEELETL-RALKEQ
AIQVTSLTQQLEQVSIVKQRSEDELQQQRDVLDGHLREKQRTQDELRRLASQVEALQQQL
LQERENARQAHVRSEHLQKAVEDKSRSLNESRLEIERLQSLTENLTKEHLLLEGELRNLR
LEYDDLQQGRSEAEHDKNATILELRSQLQISNTRTLELQGLINDLQRERGNLRQEIEKFQ
KQALEASNRIQESNNQCSQVVQERESLLVKIKVLEQEKARLQRLEDELNQAKVALEAESR
VKQRLEREKQQIQNDLNQWKTQCSRKEETVRKIESEREKSEREKNSLRSEIERLQAEIKR
IEDRCQRKLEDSSRETQSQLEIERSRLQREIDKLRQRPYGSHRETQTEYEWSVDSSKLVF
DGLRKKVTALQLYECQLIDKTTLDKLLQGKKSAEEV-ASEIQPFLRGAGAIAG---VSTS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDR
QQIYTA EKAVTGFDDPFSGKTVSVSEAIKKNLIDREIG MRLLEAQIASGGVVDPVNSVFL
PKDTALARGLIDRDLYRSLNDP RDSQKNFMDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVPISELVDSGILRPSTVNELESGQISYDEVGERI KDFLQGSSCIAGI
YSETTKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNTISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNQELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITMTGSDGSTRVLLVDRKTGSQYDVQDAIDRGLXXXXXXXXXYKSGSLS
LTQFADMISLKNGVGNS------------GGTGSGVSDDVFSSSRHE-SLSKISTVSSVR
NLTIKSRSLSETLEESSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLPLQDAVSQGLLDQDMATRLKPA QKAFLGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVQGRMSMEEAIRKGYIDGRAAQRLQDPSNYGKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSG-------
-SRSGSRSGSRRGSFDATGNSSHT-YS--Y---SISTSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC---GGGGGG-GGG--GGGG----TSR
MYY--SRRCTVTDQN-------------------SDGYGQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISAPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMMTWGVDLASVEQHIS-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNTPLQRLLEQIKELEREREKILEYK
RQVQSLVNKSKKIVQLKPRNPDYRSHKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIKAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQT
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHLGTCQDVNHNKVIETNRE
NDKQETWMLIELQKIRRQMELCESRMALKNLLLADPGSSHHITVKINELK-SVQNDSQAI
-AQ-VLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCAVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQTFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLSIPIKRTVIQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKDLNEKITRLTYEIEDEKRRRKAVEDRFD
QQKSDYDQLQKARQNEKESLGWQKMESEKAIKEKEFEIERLRVLLQE-----EGARKREY
ESELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKEEIVRLNDSILQTTEQRRRAEEDALQQKACGSEMLQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELAKVRANYDEEIISLKNQFET
EINITKTTIHQLTLQKEEDTSSYRAQIDTLTRENRSLSEEVKRLKNTLAQTTETLRRVEE
NVQQQKTTGLEMSQRKQQLEIELRQVTQMRTEESARYKQSLDDAAKTIQDKNKEIDRLKQ
LIETEASQRKCLEDENARLQRAQGELQKAHSSATETISKLKVQEQELLRLRLDYERVSQE
RTVRDQDIARFQTSLKDLQLQKQKAEEELARLKRAASEDSSKRKKLEEELEGLRRTLKEQ
AIKVTSLTQQLEQASIVKKRSEDELRQQRDVLDGHLREKQRTQDELRRLASEAEALRRQL
LQEQESVRQAQARNEHFQKAIEDKSRSLNESKIEIERLQSLTESLTKEHLMLEEELRQLR
LEYDDLRRGRSEADHDKNATIAELRSQLQISNNRTLELQGLINDLQRERENLRQEIERFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEEELSRAKTALEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERCRLQREIDRLKQRPYGSHRETQTEYEWSVDSSKLVF
DGLRKKVTAVQLHECQLIDKATLDKLLKGKKSVEEV-ASELQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAVTGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVSELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFRELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLIDRK-FFEQYRSGSLSLTQFADMISLKNGVGSGVG----GGVGSSSSTGGGLSDDVFGGSRHE-TVSKISTISSIRNLTIRSSSLSEPLEESSPIAAIFDTENLEKISISEGIERGIVDSISGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVQGRISMEEAIRKGYIDGRAAQRLQDTSTYGKILTCPKTKLKISYKDAINRSMVEDVTGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYDTFRE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLIDRK-FFEQYRSGSLS
LTQFADMISLKNGVGSGVG----GGVGSSSSTGGGLSDDVFGGSRHE-TVSKISTISSIR
NLTIRSSSLSEPLEESSPIAAIFDTENLEKISISEGIERGIVDSISGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVQGRISMEEAIRKGYIDGRAAQRLQDTSTYGKILTCPKT
KLKISYKDAINRSMVEDVTGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRS
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMIRAESGPDLRYEVTS------GGGGTSRMYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDECF--AQANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRGIHNSIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGYPQHQ----------TVTTTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFGEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWVYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGTRKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYQS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTY---SGGGGGGGGGG--GGG----TSR
TYHSHSRRCMVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQEMLQN
CSDCLMRAELIAQPELKF--GEGMQLAWNRELDEYFT--QANDQMEIIDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGAGGYTCQSGSGWDEFTKRLTGECLG
WMRQQREEMDLMAWGVDAGSVEQHIN-SHRSIHNTIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKIIEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHLGTCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEARMSLKNLLLAEQGSTHHITVKINELK-SVQNDSQAL
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVSDGYLNSLCSVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFTEKVTQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQIIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEVKRLKNTLAQTTENLRRVEE
NAQQQKATGSEMSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKH
LVDKETNERKCLEDKNSKLQRVQYDLQKANNSATEAMSKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQ
AVKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLESERCRLQKEIEKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLSVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GLG---GSVNDDVFSSSRHD-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVNQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGGY--LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYDTFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GLG---GSVNDDVFSSSRHD-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVNQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGGY---

------------------------------------------------MGRRV----SQE
CFY--PVFAGYFHIERV---------LSYLRRFLPLPHRQT-GTMSRLQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRHMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSLHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIIQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNHNKMIETNRE
NDKQETWLLMELQKVRRQIEHCESRMTLKNLLLADQPSTHHITVKINELK-SVQNDSQAL
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKAELQKAQQ
IHSQTSQQYPLYDLDLGKFNDKVIQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQNFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLSSLEELKRQAELDGKSAKQNLDKCYAQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKSDYDQLQKARQSEKESLGWQKLESEKAIKEKEYEIERLKVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKSLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEILQKKQHLEIELKQVIQQRSEDNSR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNSYDEEIISLRNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEIKRLKNTLSQTTENLKRVEE
NIQQQKATGSEMSQRKQQLEIELRQVTQMRTEESTRYKQSLDDAAKTIQDKNREIERLKQ
LVDKETSERKCLEDENARLERVQYDLQKANSSATETISKLKGQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELGRLKRTASEDSSKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKKSEDDLRQQRDVLDGHLREKQRTQEDLRRLSSEVEALRRQL
LQEQDSVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEEDHDKNAAICELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIHESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEEELNRLKATLEAEGR
LKQRLESEKQQIQNDLNQWKTQFSRKEEAIRKIESEREKSEREKNGLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERCRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPFTKKKVSYMQLRDRCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGSIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFDQYRSGSLSLTQFADMISLKNGVGGGI------------SMGGSVSDDVFSSSRHE-SVSKISTISSIRNLTIRSSSLSDPLEELSPIAAIFDTENLEKISITEAIDRGIVDSITGQRLLEAQACTGGIIHPTTGQRLLLQDAVAQGLIDQDMATRLKPAQKAFVGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRGAQRLQDTSSYAKILTCPKTKLKISYKDAVNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGSIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFDQYRSGSLS
LTQFADMISLKNGVGGGI------------SMGGSVSDDVFSSSRHE-SVSKISTISSIR
NLTIRSSSLSDPLEELSPIAAIFDTENLEKISITEAIDRGIVDSITGQ RLLEAQACTGGI
IHPTTGQRLLLQDAVAQGLIDQDMATR LKPAQKAFVGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRGAQRLQDTSSYAKILTCPKT
KLKISYKDAVNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRLNTLGRMTRAESGPDLRDMRFE---TTS-------GGGGGT-----SR
TYY--SRRCV-------------------VNDQNSDGYGQT-GTMSRMQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEVTDSLIREMRHMGQ
PCDVYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSLHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKTSFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLSQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIIQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNPNKMIETNRE
NDKQETWLLMELQKVRRQIEHCEGRMTLKNLLLTDQPSTHHITVKINELK-SVQNDSQAL
A--EVLNQLKDVLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLFTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKAELQKAQQ
IHCQTSQQYPLYDLDLGKFNDKVIQLTD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQNFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLSSLEELKRQAELDGKSAKQNLDKCYAQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKSDYDQLQKARQSEKESLGWQKLESEKAVKEKEYEIERLKVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKHSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNSYDEEIISLRNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEIKRLKNTLAQTTENLKRVEE
NIQQQKATGSEMSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNRELERLKQ
LVEKESSARKCLEGENARLERVQYDLQKANSSVTETISKLKGQEQELTRLRIDYERVSQE
RNVKDQDIARFQSSLKELQLQKQKVEEELSRLKRTACEDSSKRKKLEEELEGMRRSLKDQ
AIKITSLTQQLEQVSIVKKKSEDDLRQQREVLDGHLRDKQRTQEDLRRLSSEVEALRRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEEDNDKNAAICELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIHESKSQCTQVVQERESLLVKIRVLEQEKVRLQRLEEELNRLKATLEAEGR
VKQRLESEKQQIQNDLNQWKTQYSRKEEAMRKIESDREKSEREKNTLRSEIERLQAEIKR
IEERCRQKLEDSSRETQSQLETERSRLQREFDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGVIDPHRNEKLTVDNAIARDLI DFDDR
QQIYMAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGIVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPFTKKKVSYVQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVNIAYKRGYFNEELSEILTDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFDQYRSGSLSLTQFADMISLKNGVGSSI------------SMGSGVSDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISVSEAIDRGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAMAQGLIDSDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVNIAYKRGYFNEELSEI LTDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFDQYRSGSLS
LTQFADMISLKNGVGSSI------------SMGSGVSDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISVSEAIDRGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAMAQGLIDSDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRS
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTS------GGGGTSRIYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRDLDECF--AQANDQMEILDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAHATEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAV
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYLLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSATESINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSCEVEALRRQL
LQEQDSVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDR
QQIYT AEKAITGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGLELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC---GGG---GGGGG-GGGG----ASR
MYY--SRRCAVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLGRSRELDEYFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDKNTDIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEREREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNKERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTQTEITHVGSCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEGRMTLKNLLLTDQASSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLSSLCSVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFNEKVIQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYSQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEFEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQDEAKRRWEYENELSKVRHSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLAQTTENLRRVEE
NVQQQKATGSEVSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LVEKESNERKCLEDENSKLQRVQYDLQKANNSATETISKLKVQEQELTRLRIDYERVSQE
RTVKDQDIVRFQSSLKDLQLQKQKVEEELSRLKRTASDDSSKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSLEVEALRRQL
VQEQENAKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLTISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQDDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRLQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKATLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASVS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDIALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIDRK-FFDQYRSGSLSLTQFADMICLKNGVGNGT---------SM---TGGINDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFMGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIDRK-FFDQYRSGSLS
LTQFADMICLKNGVGNGT---------SM---TGGINDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFMGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGH----

--------------------------SRESGRWG---TANG---PTGESGEGL-----PG
VFL--FCFCN-------------------ECSSCFQIDHQM-GTMSRLQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLSRSRELDECFA--QANDQMEVTDSLIREMRHMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRMTSECLG
WMRQHRAEMDMVAWGVDLASVEQHIN-SHRGLHNAIGDYRWQLDKIKADLVL--------
---CWLPKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTDIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIIQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDANHNKMIETNRE
NDKQETWLLMELQKVRRQIEHCEGRMTLKNLLLTDQPSTHHITVKINELK-SVQNDSQAL
A--EVLNQLKDVLANFRGSEKYCYLQNELFGLFQKLENINGVTDGYLNSLCPVRSLLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKAELQKAQQ
IHCQTSQQYPLYDLDLGKFNDKVIQLTD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQNFCKWLYDAKRRQDSLESMKFGDSNTVMRFLTEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLSSLEELKRQAELDGKSAKQNLDKCYAQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKSDYDQLQKARQCEKESLGWQKLESEKAVKEKEYEIERLKVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKSLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKHSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNSYDEEIISLRNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEIKRLKNTLAQTTENLKRVEE
NIQQQKATGSEMSQRKQQLEIELRQVTQMRTEESTRYKQSLDDAAKTIQDKNREIERLKQ
LVEKETSERKCLEDENARLERVQYDLQKANSSATEAISKLKSQEQELTRLRIDYERVSQE
RTVKDQDIARFQSSLKELQLQKQKVEEELSRLKRTACEDSSKRKKLEEELDCMRRSLKEQ
AIKITSLTQQLEQVSIVKKKSEDDLRQQRDVLDGHLRDKQRTQEDLRRLSSEVEVLRRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEEENDKSATICELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIHESKSQCTQVVQERESLLVKIKVLEQDKVRLQRLEEELNRLKATLEAEGR
VKQRLESEKQQIQNDLNQWKTQYSRKEEAIRKIESDREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERSRLQREFDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-AAEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGIVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPFTKKKVSYVQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVNIAYKRGYFNEELSEILTDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFEQYRSGSLSLTQFADMISLKNGVGGSI------------SMGSGVSDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISVSEAIDRGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVAQGLIDTDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAMNRSMVEDVTGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---TFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVNIAYKRGYFNEELSEI LTDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFEQYRSGSLS
LTQFADMISLKNGVGGSI------------SMGSGVSDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISVSEAIDRGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVAQGLIDTDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDVTGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---TFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTC---GGGGGGGGGYGGGFGG----TTR
MYC--SRRCTTTDQN-------------------SDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDEYFA--QANDHMEIADSLIREMRQMGQ
PCDTYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRVTSDCLG
WMRQQKAEMETVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFDRMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNTERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYLKTIQDLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHLGTCQDANHNKVIETNRE
NDKQETWMLIELQKIRRQMEHCEGRMSLKNLLLADQGSTHHITLKINELK-SVQNDSQGI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVYLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLHDAKRRQDSLESMKFGDSNTVMRFLNDQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRAMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDKLCRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACSSEMMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELGKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGFRAQIDNLTRENRSLCEEIERLKNTLAQTTENLRRVEE
NVQQQKAAGTEVSQRKQQLEIELRQVTQIRTEESMRYKQSLDDAAKTIQDKNKEIDRLKQ
LIDKETNERKCLEDENAKLQRVQYDLQKANSSATETITKLKGQEQELTRLRIDYERVFQE
RTVKDQDITRFQNSLKELQLQKQKVEEELTWLKRTASDDSSKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLEGHLREKQRTQEDLRRLSSEVEALRRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEVDSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLMVKIKVLEQDKARLQRLEDELNRAKAALEAESR
AKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESDREKSEREKNGLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLESERCRLQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVDA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFLDPVTKKKVSYVQLKERCRIEPHTGLLLLTV
QKRSMSFQGIRQPVTVTELVNSGILRQSTVHELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIERK-FFDQYRSGSLSLTQFADMISLKNGVGGSG---------SVG--G-SVSDDVFSSSRHD-SVSKISTVSSIRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLLLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-K-KMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISNEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYRDAINRCMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRPGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYS-YS--Y---TFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYDTFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIERK-FFDQYRSGSLS
LTQFADMISLKNGVGGSG---------SVG--G-SVSDDVFSSSRHD-SVSKISTVSSIR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLLLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-K-KMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISNEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYRDAINRCMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRPGSRSGSRS
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---TFSSSSIGH----

------------------------------------------------------------
---------------------------------------QT-GTMSRHQNQNTIQDLLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANEQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDAIRKKYPCDKNMPLQRLLDQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGYPQHQ----------TVTKTEITHVGPCQDVNHTKVIETNRE
NDKQETWMLIELQKIRKQMEHCEARMTLKNILLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCAVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEICGKRDKSEEVQKIAEL
CANAIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQSEKESLGWQKIESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ESELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISLQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEEDALQQKASGSEMMQKKQHLEIELKQVIQLRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELAKVRNNYDEEIISLKNQFET
EINITKTTIHQLSMQKEEDTSGYRAQIDNLPRENRSLSEEIKRLKNTLAQSTENLRRVEE
NIQKQKATGSEMSQRKQQLEIELRQVTQMRTEESTRYKQSLDDAAKPIQD-NKEIERLKQ
LIETETKERKCLEDENAKLQRAQYDLQKANNSATETISKLKVQEQELMRLRVDYERISQE
RTVKDQDITRFQSSLKELQLQKQKADEELNRLKKTASEDSSKRKKLEEELEGLRRSLKEQ
AIKITSLTQQLEQASIVKKKSEDDLRQQRDVLDGHLREKQRTQEELRRLSLEVEALRRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTESLTKEHLMLEEELRNLR
LEYDDLRRGRSEADNDKMATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERETLLMKIKVLEQDKTRLQRLEDELNRAKTTLEAESR
VKQRLESEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERYRRKLEDSTRETQSQLETERSRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGVIDPHRNEKLTVDSAIARDLIDFDDR
QQIYT AEKAITGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFVDPVTKKKVSYMQLRDRCRIEPHTGLLLLSV
QKRSMSFQGIRQLVTISELVASGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKEG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLL-----------------------------------------------------------------------------LELLEAQAATGFIVDPVSNLRLPVEEAYKEG----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLL------------------------------------
----------------------------------------------

-----ISCSHPRINTLGRMIRAESGPDLRYEVTS------GGGGTSRMYYS---------
------RRG-------------------VITEQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDECFA--QANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNSIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGYPQHQ----------TVTTTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFGEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGTRKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPASRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPASRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC---GGIGGGGG---GGGGG----TSR
MYY--SRRCTVTEQN-------------------SDGYGQT-GTMSRHPNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLSRSRELDEYFA--QANDQMEITDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISAPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRVEMDTVAWGVDMASVEQHIN-SHRSLHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQSIIQAASREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLSQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNTPLQRLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIIHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQT
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHVGSCQDVNHHQVIELNRE
TDKQETWILMELQKVRRQMEHCEGRMTLKNILLADQGSSHHITVKINELK-SIQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCTVRSLLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDNLESMKFGDSSTVLRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYSSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKAAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKAVEDRFD
QQKNDYDQLQKARQCEKESLGWQKIESEKAIQEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINVTKTTIKELSLQREDDAKSLRGQLDRLSRENRD
LKDEIVRLNDSLLQTTEQRRRAQEDALQQKACGSEMLQKKQQLEVELKQVIQQRSEDNAR
HKQSLEEAARTIQDKNKEIERLKAEFQEEAKRRREYESELAKVRSSYDEEIISLKNQFET
EINITKTTIHQLTLQKEEDTSGYRAQIDGLTRENRSLSEEVKRLKNSLAQTTESLRRVEE
NVQQQKATGLEMSQRKQQLEVELRQVTQMRMEESARYKQSLDEAAKTIQDKNREIERLKQ
LVETEAKERKCLEEENAQLQRAHGDLQKAHGSATETISKLKVQEQELLRLRMDYERVSQE
RAARDQDIARFQSSLKELQVQKQKAEEELARLKRAASEDSSKRKKLEEELEAMRRSLKEQ
AVKVTSLTQQLEQASISKKRSEDELRQQRDVLEGQLREKQRTQDELRRLASEVEALRRQL
LQEQENLKQAHMRSEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDFRRGHSEVDHGKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEEELNRAKATLEAESR
LKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNTLRSEIERLQAEIRR
IEERCRRKLEDSSRETQSQLETERCRLQREIDKLKQRPYGSHRETQTECEWAVDSSKLVF
DGLRKKVTAMQLFECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKDKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAVTGFDDPFSGKTVSVSEAIKKNLIDRETGL RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDGQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVSELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEATGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGFIDRK-FFDQYRSGSLSLTQFADMISWKNGVTSTG---------GGGGTGGSVSDDVFSTSRHE-AVSKIATIASARNLTIRSSSLSDPLEEWSPIAAIFDTENLEKISVTEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVAQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVNGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATSNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEATGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGFIDRK-FFDQYRSGSLS
LTQFADMISWKNGVTSTG---------GGGGTGGSVSDDVFSTSRHE-AVSKIATIASAR
NLTIRSSSLSDPLEEWSPIAAIFDTENLEKISVTEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVAQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVNGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATSNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMIRAESGPDLRYEVTS------GGGGTSRMYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDECF--AQANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRGIHNSIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGYPQHQ----------TVTTTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFGEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGTRKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC---GGVGGGGG--G-GGGG----TSR
MYY--SRRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CADCLMRAELIAQPELKY--GDGIQLARSRELDECFA--QANDQMEITDNLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGECLG
WMRQQRAEMDLMAWGVDLGAVEEHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEGRMTLKNLLLTDQGSTHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSVRALLQAV
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHAQSSQQYPLYDLDLGKFSEKVMQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHGEISGKRDKSEEVSKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQSEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRVTRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEMELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQDEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
NVQQQKATGSEMSQRKQQLEMELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LVEKETNERKCLEDENSKLQRVQYDLQKANSSATETISKLKVTEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASDDSSKRKMLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLESEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERCRLQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKATLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAVTGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVNSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLREKKKQVQTSQKNTLRKRRVVIVDPETDKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGIGNSG---------GLS--SSGVNDDVFSSSRHE-SVSKISTVSSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLREKKKQVQTSQKNTLRKRRVV IVDPETDKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGIGNSG---------GLS--SSGVNDDVFSSSRHE-SVSKISTVSSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC---GGVGGGGG--G-GGGG----TSR
MYY--SRRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CADCLMRAELIAQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGECLG
WMRQQRAEMELIAWGVDSGAVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEGRMTLKNLLLTDQGSTHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSIRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKSDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFNEKVMQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQDEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTDNLRRVEE
NVQQQKATGSEMSQRKQQLEIELRQVTQMRTEEGLRYKQSLDDAAKTIQDKNKEIERLKQ
LVEKETNERKCLEDENSKLQRAQYDLQKANNSATETISKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRSASDDSSKRKMLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
VEERCRRKLEDSTRETQSQLETERCRHQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GLG---GGVNDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS-SS-YSYSY---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GLG---GGVNDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS-SS-YSYSY---SFSSSSIGH----

------------------------------------------------------------
----------------------------------------------MSRRQNTIQELLQN
CADCLTRAELIVQPELKY--GDGVPLRGNRDLEECFA--QANDQMDILDGLIREMRQMGQ
PCDMYQKRLLQLQEQMRALYKAISVPRARRASSKGGGCFSSQSGSGWDEYTKRVTSECLS
WMRQQKVEMEQVKWGFDAASIEQQIG-EHRRTHNAIGDYRWHLDKVKTDLREKAAVHQLE
EEYEGLLKYSFERMDQLRQFQNLIQATSREIMWINDCEEEELLYDWSDRNTDIARKQESF
SKRMSELEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQATECYLKNLQDSIRKKFICDKSMSLQTLLEQIKELENERERILEYK
RQVQSLVNKSRKIVQLKPRNPDYRSNKPIILKALCDYKQDLKTVRKGDECILKDNNERSK
WLVTGPGGVDMLVPSVSLIIPPPNPLAVDLATKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRKEDYQKIITDLEIHYQEFLRNSQGSEMFGDEDKRKMQT
QFTDAQKHYQTLIIQLPNQPRQPQ---------TVVPTESCPVGSS---NTIIVNERNRE
HEKQEAWLLMELQKLRRQIEAAEIQMVQRAPLGVDQGAMHDFSVRIKDLE-GVQNDSQIM
A--ETLNKHKDLLPNFRGCEKYVYLQSEINALFQKLENINGVSAGYLDSLNALRCLLQVI
LQTEDVIRVFEVRLSEEETVPLDLDKVEAYRACLKKMKTDLNMKKSLLNTLENELQRTLQ
IHSQSCQSYTLYDMDIGKYCDKVTQLID---RWQRADKQIDNRSWDLERQIKQLKTYRD-
LYQALCKWICDAKRRQDSIESVKLCDSNTIMRYLHDQKNLHSEICGKRDKVEELLKHADQ
CSAAIKDYELQVASYSSGLETLLNIPIKKSVVQSPAVLILQEANEAQSRYIELLTRSGDY
YRFLSEMLKSMEDLKMKNTKIELLEEELRLARDSNSETSNKHKFLEQNLQKYQMDISQLK
AKLMSLEEMKRQAEMDGNSAKQNLDKCYAQIKDLNDRITRLTYETEDEKRKRKLLEDRYE
QQKNDYDQLQKTRQNEKDSLGWQKLESEKVIKEKEYEIERLRVLLQD-----EGTRKREY
ENELAKASS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--------RIQESKNQYSHIMQERETLLIKMSALEQDKARLQRLEEELNRLKVTLESESR
SKQRLESEKQQILNDLNQWKSQHSRTEESIRKIQCEREKSEREKNSLRSEIERLQMEIKR
IEERYRCRLEETAVKNQSELESERLRLQREIEKLKQRPYGAHRSTQTEEDFCIDASKLVF
SGLRKKITAMQLYECQLIDKLTLDKLLKGQRSVEEV-AADIEPYLKGAGAIAG---VSLS
PRQKYSFVEA-KRNQLLTAENAVLLLEAQAATGGVIDPHRNEILTVDSAIARDLIDFDDR
EQIYT AEKAITGFKDPFSGKTVPVSEAIKKNLVDRETG IRLLEAQLAVGGIVDPVNSVFL
PKEVALSRGLIDKDLYRMLN NCQGNTKNFIDPTTKKAVTYMQLKEKCRIEPHTGLLLLPV
QKRSMSFQGIRQPVSADALLEAGIIKESTRNDLERGAITVEEVSERIID FLQGSSCIAGI
YNEATKEKLGIYQAMKIGLVRPGTALELLEAQAATGFIVDPVSNVRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYKDPETGNIISLFQAMNKELIERGHGIRLLEAQIATGGIIDPKESYRLPVETAYKRGYFNEELNQILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDDATGLCLLPLREKKKVVHTSQKNTLRKRRVVIVDPETNREMSVQEAYSKGLIDYDTYTELAEQ---------ECEWEEITITGSDGSSRVVLVDRKTGSQYDIQDAIDKGLVERK-FFDQYRSGSLSLTQFADMISCRNGTDEVFRH-----------------------ESVTRSPTVLSVRSSSSVIR--SGSFSDTPDECSPIAAIFDTENLEKISISEAIQRGIVDSITGQRLLEAQACTGGIICPTTGQRLSLQEATSQGIIDQDMATRLKPAQKAFIGFEGIKGGRKRMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVRGRITTEEAIRNGLIDGRAAQKLQDTNSYPKILTCPKTKLKISYKDAMNRSMVEDITGLKLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------GSRSGSRSGSRRGSFDASASSSYS-YSYSA----FSSGSILELLEAQAATGFIVDPVSNVRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYKDPETGNIISLFQAMNKELIERGHG IRLLEAQIATGGIIDPKES
YRLPVETAYKRGYFNEELNQILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDDATGLCL
LPLREKKKVVHTSQKN TLRKRRVVIVDPETNREMSVQEAYSKGLIDYDTYTELAEQ----
-----ECEWEEITITGSDGSSRVVLVDRKTGSQYDIQDAIDKGLVERK-FFDQYRSGSLS
LTQFADMISCRNGTDEVFRH-----------------------ESVTRSPTVLSVRSSSS
VIR--SGSFSDTPDECSPIAAIFDTENLEKISISEAIQRGIVDSITG QRLLEAQACTGGI
ICPTTGQRLSLQEATSQGIIDQDMATRLKPA QKAFIGFEGIKGGRKRMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVRGRITTEEAIRNGLIDGRAAQKLQDTNSYPKILTCPKT
KLKISYKDAMNRSMVEDITGLKLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------
GSRSGSRSGSRRGSFDASASSSYS-YSYSA----FSSGSIGR----

------------------------------------------------------------
-------------------------------MSCNGGSHQT-GTMSRLQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRHMGQ
PCNAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQHRAEMDMVAWGVDLASVEQHIN-SHRSLHNAIGDYRWQLDKIKADL----------
-------KASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SVRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQLTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNHNKMIETNRE
NDKQETWLLMELQKVRRQIEHCEGRMTLKNLLLVDQPSTHHITVKINELK-SVQNDSQAI
A--EMLNQLKDLLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLQATMKAELQKAQQ
IHCQTSQQYPLYDLDLGKFNDKVVQLTD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQNFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLSSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQSEKESLGWQKLESEKAIKEKEYEIERLKVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNIRNKYETEINISKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKASGSEILQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNSYDEEIISLRNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEIKRLKNTLAQTSENLKRVEE
NVQQQKATGSEMSQRKQQLEIELRQVTQMRTEESVRYKQSLDDAAKTIQDKNREIERLKQ
LVEKETSDRKRLEEENARLERIHYDLQKANSSASETISKLKGQEQELTRLRIDYERVSQE
RTVKDQDIARFQSSLKELQLQKQKAEEDLSRLKRTASEDSSKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKKSEDDLRQQRDVLDGHLREKQRTQEDLRRLSSEVEALRRQL
LQEQDNVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEEDQDKNATICELRNQLQLSNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIHESKSQCTQAVQERESLLVKIKVLEQDKTRLQRLEEELSRLKATLEAEGR
VKQRLESEKQQIQNDLNQWKTQYSRKEEAIRKIETEREKSEREKNGLRSEIERLQAEIKR
IEERYRRKLEDSSRETQSQLETERCRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYMQLRDRCRIEPHTGLLLLTI
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLVDKK-FFDQYRSGSLSLTQFADMISLKNGVGSSI------------SMGGSISDDVFSSSRHE-SVNKISTISSIRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEAIDRGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVAQGLIDQDMSTRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEMHGRISTEEAIRRGFIDGRAAQRLQDTSTYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLVDKK-FFDQYRSGSLS
LTQFADMISLKNGVGSSI------------SMGGSISDDVFSSSRHE-SVNKISTISSIR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEAIDRGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVAQGLIDQDMSTR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEMHGRISTEEAIRRGFIDGRAAQRLQDTSTYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

------------------------------------------------------------
-------------------------------------FSQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISAPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRSEIEVMEMQIRKIISAQPILRWGQKCHHQASEICLQTDWEKSLWREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNTPLQRLLEQIKELEREREKILEYK
RQVQSLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIKAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQT
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHLGTCQDVNHNKVIETNRE
NDKQETWMLIELQKIRRQMELCESRMALKNLLLADQGSSHHITVKINELK-ESVDQPSAG
KASLMKDRKGQLSPNFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCAVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLSIPIKRTVIQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKDLNEKITRLTYEIEDEKRRRKAVEDRFD
QQKSDYDQLQKARQNEKESLGWQKMESEKAIKEKEFEIERLRVLLQE-----EGARKREY
ESELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKEEIVRLNDSILQTTEQRRRAEEDALQQKACGSEMLQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELAKVRANYDEEIISLKNQFET
EINITKTTIHQLTLQKEEDTSGYRAQIDTLTRENRSLSEEVKRLKNTLAQTTETLRRVEE
NVQQQKTTGLEMSQRKQQLEIELRQVTQMRTEESARYKQSLDDAAKTIQDKNKEIDRLKQ
LIETEASQRKCLEDENARLQRAQGELQKAHSSATETISKLKVQEQELLRLRLDYERVSQE
RTVRDQDIARFQTSLKELQLQKQKAEEELARLKRAASEDSSKRKKLEEELEGLRRTLKEQ
AIKVTSLTQQLEQASIVKKRSEDELRQQRDVLDGHLREKQRTQDELRRLASEAEALRRQL
LQEQESVRQAQARNEHFQKAIEDKSRSLNESKIEIERLQSLTESLTKEHLMLEEELRQLR
LEYDDLRRGRSEADHDKNATIAELRSQLQISNNRTLELQGLINDLQRERENLRQEIERFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEEELSRAKTALEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERCRLQREIDRLKQRPYGSHRETQTEYEWSVDSSKLVF
DGLRKKVTAVQLHECQLIDKATLDKLLKGKKSVEEV-ASELQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDR
QQIYT AEKAVTGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVSELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLIDRK-FFEQYRSGSLSLTQFADMISLKNGVGSGVGGGMGGGVGGSSSTGGGLSDDVFGGSRHE-TVSKISTISSIRNLTIRSSSLSEPLEESSPIAAIFDTENLEKISISEGIERGIVDSISGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVQGRISMEEAIRKGYIDGRAAQRLQDTSTYGKILTCPKTKLKISYKDA--------------------------------------------------------------------------------------------LELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLIDRK-FFEQYRSGSLS
LTQFADMISLKNGVGSGVGGGMGGGVGGSSSTGGGLSDDVFGGSRHE-TVSKISTISSIR
NLTIRSSSLSEPLEESSPIAAIFDTENLEKISISEGIERGIVDSISG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVQGRISMEEAIRKGYIDGRAAQRLQDTSTYGKILTCPKT
KLKISYKDA---------------------------------------------------
----------------------------------------------

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTG---GGGG----------------TSR
MYY--SRRYTVTDQN-------------------SDGYGQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRVTGECLG
WMRQQRGEMDMISWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRHLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVSLIIPPPNPLAVDLAGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVKTTEITHHGSCQDANHNKVIETNRE
NDKQETWMLMELQKMRRQIEHCEGRMTLKNILLADQGSSHHIIVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVYLDLDKVEAYRCGLKKIKNDLNLKKSLLATMTTELQRAQQ
IHSQTSQQYPLYDLDLIKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKHAEL
CANSIKDYELQLASYTSGLETLLNIPIKRSMVQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXX
XXXXXXXXXXXXXXXXXXXXKFETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEEDALQQKACGSEVMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEQAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELAKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEDDTSGYRTQIDNLTRENRSLSEEIKRLKNTLAQTTENLRRVEE
TAQQQKATGSEVSQRKQQLEIELRQVTQIRTEESLRYKQSLDDAAKTIQDKNREIDRLKQ
LVETETKERKCLEDENAKLQRAQYDLQKAKNSATETISKLKVQEKELTRLKIDYERISQE
RSVKDQDITRFQNSLKDLQVQKQKVEDELNWLKRTASDDSSKRKQLEEELEGMRKSLKEQ
AVKITSLTQQLEQVSIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSLEVEALKRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRNEVDSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKIRLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRDTQSQLETERCRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASTS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDR
QQIYTA EKAITGFDDPFSGKTVSLSEAIKKNLIDRETG MRLLEAQIASGGIVDPVNSVFL
PKDVALARGLIDRDLYRSLNDP RDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVSELVDSGILGMSTVNELESGRISYDEVGERI KDFLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSDILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS------------SMGGSASDDVFSNSRHE-SVSKISTISSVR
NLTIKSSSLSEPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQDAISQGLIDQDMATRLKPA QKAFIGFEGMKR-K-KMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFID-RAAQRLQDTSSYAKFLTWPQT
K-KISYKDAMNRSMVEDI------------------------------------------
----------------------------------------------

--MSCNGGSHPRINTLGRLTRAESGPDLRYEGTC---GGGGGG-------GGT----TTR
MFY--SRRCGVAEQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCEAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGDCLG
WMRQQRAEMDLIAWGVDLASVEQHVN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTDIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNTPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WCVTGPGGVDMLVPSVGLIVPPPNPLAVDLSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------T--------------------------
---------------------------------------------------SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCSARALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYVELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYAQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQSEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKA-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------SNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEEELTRAKATLEAECR
VKQRLESEKQQIQNDLDQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERCRLQREIDRLRQRPYGAHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDRLLQGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAVTGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVAVARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYAQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYKTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQESIDKGLVDRK-FFDQYRSGSLSLTQFADMVSLKNGFGNNG---------------SGVSDDVFSSSRHE-SVSKISTVSSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVTQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDGTGSS--S-YSYSY---MFSSSSIGHS--LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYKTFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQESIDKGLVDRK-FFDQYRSGSLS
LTQFADMVSLKNGFGNNG---------------SGVSDDVFSSSRHE-SVSKISTVSSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVTQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDGTGSS--S-YSYSY---MFSSSSIGHS---

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC---GGVGGGGGGGG-GGGG----TSR
MYY--SRRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CADCLMRAELIAQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGECLG
WMRQQRAEMDLMAWGVDSGAVEQHIN-NHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEGRMTLKNLLLTDQGSTHHITVKINELK-SVQNDSQAI
A--DVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFSEKVMQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDTNTVMRFLNEQKNLHSEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQDEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
NVQQQKATGSEMSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LVEKETNERKCLEDENSKLQRVQYDLQKANNSATETISKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASDDSSKRKMLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERCRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETDKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQEAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVANNG---------GLS---GSVNDDVFSSSRHESSVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDVSSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSSS-YSYSY---TFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETDKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQEAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVANNG---------GLS---GSVNDDVFSSSRHESSVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDVSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSSS-YSYSY---TFSSSSIGH----

MSMNGGGGSHPRLNTLGRMIRTESGPDMRYEMNPYMMGGGGGGGGGGGGGGGGSSSHTHK
MYYVQ--KT-------------------YGGDHSSDGYVQN-GTGTMSRRQNTIQEMLQN
CSDCLMRAELIVQPELKY--GEGIQISRNRELEDCFV--QANEHMDILDGLIREMRQMGQ
PCDLYQKRLLQLQEQMRALYKAISVPRVRRASSKGG--YTSQSGSGWDEYTRRATTECLN
WMRQQKADMELVKWGFDAASIEQQIA-DHRRFHNSIGDYRWHLDKVKTDLREKAAIHQLE
EEYEYLLRFSFERMDQLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTDIARKQEAF
SKRMSQLEVKEKELNKLKQECDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTENYLKNLQDSIRKKFICDKNMSLQVLLEQIKELENEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSSKPIILRALCDYKQDLKTVRKGDECILKDNSERSK
WHVTGPGGVDMLVPSVSLIIPPLNPLAVDLATKIEQYYDAIMALWNQLYINMKSLVSWH-
YCLIDIEKIRAL-TIAKLKTMRREDYQRVIDDLEIHYHEFLRNSQGSEMFGDDEKRKIQT
QFTDAQKHYQTLVIQLPPQQQQQQK-----QPQQIVPTEVIHVGSS---NQVQVPDR-FQ
LEKQEAWLLMELQKLRRQIENCELRMVQRTPLQLDQGASHNLSVRICELE-GVQNESQAM
A--EALNRQNDYLPNFRGSEKYIYLQSEINALFSKLENINAVSAGYLDSLNALRSLLQAI
LQTDDVIRVIEVRLTEEDTLSLDPDKVEAYRASLKKMKADLSAKKSLLSILEAELQKVLQ
IHSQSSQSYVLYGLDLGKYTDKVNQLTD---RWQRVEKQIDDRSWDLEKQVKQLRTYRD-
IYQALNKWIGDAKRRQDTIESMKLGDVSTVMRYLQEQKNLHSEVTGKRDRVEEVVKNAEV
CSAAIKDYELLAATYSSGLETLLNIPLKRTVVQSPSGLILQEAAEIQTRYIELLTRSGDY
YKFLSEMLKSLEDLKMKSTKIELLEEELRLARDANSDNSNKHKFLEQNLQKYQLEISQLK
AKFMSLEEMKRQAEMDGSSAKQNLDKCYGQIKDLNDRITRLTYEIEDEKRKRKLLEDRYE
QQKTDFDQLQKTRQNEKEGLGRQKIETEKIVKEKEYEIERLRVLLQD-----EGTRKREY
ENELAKVRNQFNEEMSNIKNKYETEINIKKTTIHQIASQKEDDAKNLRSQIDRLQRENRD
LKDEIVRLNNTILETTDQRRRAEENILQQKACGSELMQQKQTLELELKQIIQLRNEDNGK
YKQALEDAASTIQERTKELERLKIQLQEEAKNRWELENELAKVRNSYDEEIISLKNKYET
EINITKTTITQVTVQKEEESNNYRTQLDNVIRENRSLCEEIRRLKKTISQTTENLRQVEE
SAQQQKAISSEISQKKHQIEIEFKQTVQKYSDENMRYKQSLDDSARTIKEKNKEIEKLRK
LLEAETNQRKSMEEENIRLQRVQFDLEKVNINATETISRLKGQEQELGRLKSEYERLAQD
KKGKDQESTRLQSKVKDLQHQKHTLEEELNRQSRTLAEETSKKKKVEEELETLRRSFRDQ
AVKITNLTQQIEEVSIIKKRSEDDLRHQREVLDNHMRDKQRYMEEARKYTLEVETLRRQM
VQEQENLKQAHVRNEHLQKAIEDKSKSLNECKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGKTEVDEEKNATIIDLRSQLQTSSKHTLELQGLINGLQKERDNLRQEIEKFQ
KQALEASHRIQESKNQCNHVMQEREALLIKINTLEQDKARLLRLEEELNRSKSTLDSETR
LKMRLENEKQQIMNDLNQWKSQYSRKEETIRKIESERDKSDREKSALLVEIERLQAEIKR
IEERYRSRLEETSRKSQSEMEAERLRLQREIERLKQRPYGAHRCTQTEEDFAIDASKLLF
NGLRKKITAVQLYECQLLDKCTLDKLLRGQKSVEEV-AADLEPYLKGAGAIAG---ASLN
PKEKYSLVEA-KRKQLLTPENTILLLEAQAATGGVIDPHRNEFLSVDSAVARDLIDFEDR
EQIYT AEKAISGFKDPFSGKTVPVAEAIKKNLVDRDTG IRLLEAQLAAGGIVDPINSIFL
PKDIALSRGVIDRELYRTLNN P---SKNLIDPITKKAISYMKLREKCRIEPHTGLLLLPV
QKRSMSFQGIRKPIPVSELVESGIIRESTANDLETGAITVEEVTDRIKD FLQGSSCIAGI
YNEATREKLGIYQAMKIGLVRPGTALELLEAQAATGFIVDPVSNSRLTVEEAYKRGLVGIEFKEKLLSAEKAVTGYKDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVHTAYQRGYFNEELNDILSDPSDDTKGFFDPNTEENLTYLQLKERCIIDDGTGLCLLPLRERKKLVQTSQKNTLRKRRVVIVDPDTGKEMSVQEAYNKGLIDYDTYMDLCDQ---------ECEWEEITITGSDGSTRVVLVDRKTGNQYDIQDALDKGLVDRK-FFDQYRSGSLSLTQFADMIACRNGADEVFRH-----------------------EAITRSPTVLNIKSASLVLKSASGSFSESLEETTPIAAIFDTENLEKISILEAVQRGIVDSITAQRLLEAQACTGGIICPTTGQRLSLEDARTQGLLDHDMATRLKPAQKAFIGFEGIKG-RNRMSAAEAVKEKWLPYEAGQRFLEFQFITGGLIDPEARGRISTEEAIRKGLIDGRTAQRLQDTGNYGKILTCPKTKLKISYKDAMNRSMVEDQSGLRLLEASSVSSKGISSPYNVSSAPGSRSGSRS--------GSRSGSRSGSRRGSFDAGTSGSYS-YSYTT----VSSSSSSLELLEAQAATGFIVDPVSNSRLTVEEAYKRGLVGI
EFKEKLLSA EKAVTGYKDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVHTAYQRGYFNEELNDILSDP SDDTKGFFDPNTEENLTYLQLKERCIIDDGTGLCL
LPLRERKKLVQTSQKN TLRKRRVVIVDPDTGKEMSVQEAYNKGLIDYDTYMDLCDQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGNQYDIQDALDKGLVDRK-FFDQYRSGSLS
LTQFADMIACRNGADEVFRH-----------------------EAITRSPTVLNIKSASL
VLKSASGSFSESLEETTPIAAIFDTENLEKISILEAVQRGIVDSITA QRLLEAQACTGGI
ICPTTGQRLSLEDARTQGLLDHDMATRLKPA QKAFIGFEGIKG-RNRMSAAEAVKEKWLP
YEAG QRFLEFQFITGGLIDPEARGRISTEEAIRKGLIDGRTAQRLQDTGNYGKILTCPKT
KLKISYKDAMNRSMVEDQSGLRLLEASSVSSKGISSPYNVSSAPGSRSGSRS--------
GSRSGSRSGSRRGSFDAGTSGSYS-YSYTT----VSSSSSSSFGRQ

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTY---SGGGGGGGGGG--GGG----TSR
MYYS--RRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIAQPELKF--GEGMQLACNRELDEYFT--QANDQMEIIDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGAGGYTCQSGSGWDEYTKRLTGECLS
WMREQREEMDMVAWGVDAGTVEQHIN-THRSLHNTIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKIIEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHLGACPDVNHNKVIETNRE
NDKQETWLLMELQKIRKQMEHCEARMMLKNLLLAEQGSTHHITVKINELK-SIQNDSQAL
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQSLQQYPLYDLDLGKFMEKVTQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
TAQQQKATGSEMSQRKQQLEIELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LVDKETNERKCLQDENSKLQRVQYDLQKANSSATEAMGKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSVDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLESERCRLQKEIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFPGIRHPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GLG---GSVNDDVFSSSRHD-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVNQGLIDQDMATRLKPAQKAFIGFEGVKG-K-KMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGY---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYDTFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GLG---GSVNDDVFSSSRHD-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVNQGLIDQDMATR LKPAQKAFIGFEGVKG-K-KMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGY----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTYGGAGGG----------GGATN---GR
MCC--TRRC-------------------TVAEVTSDGYCQT-GTLSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGLQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISAPRVRRVSSKGGGGYTCQSGSGWDEFTKRLTSDCLG
WMRQQRTEMDMVTWGVDLMSVEQHIN-SHRGIHNAIGDYRWQLDKIKADLXXXXXXXXXX
XXXXXXXKASFDRMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYSCDKNMPLQRLLDQIKELEKERELILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYQQDQKIVHKGDFCILKDNNDRSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRNIQT
QFTDAQKHYQTLVIQLPGHPHHQ----------TVTTTEITHLGSCQDANHKNVIEINRE
TDKQETWILMELQKIRQQMEHCEGRMWLKNTLLADQGSSHHITVKINELK-GVQHDSQAI
A--EVLNQLKDRLANFRGSEKFCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAL
LQAEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFSDSNTVMRFLNEQKNLHNEICGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVIMQEXXXXXXXYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXYDQLQA--QCE---TQWLHTESESIR--DE------YIERSL-----QGGTKREY
ENELAKVRNHYNEEMSN-RNKYETEINITKTTIKEISMQKEDDSKNLRNQLERLSRENRD
LKDEIVRLNDSILQTTEQRRRAEENALQQKACGSEILQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKTEFQEEAKRRWEYETELAKVRNSYDEEIISLKNQFET
EINITKTTIHQLTLQKEDDTSGYRAQVDKLTRENRSLAEEIKRLKTTLAQTTDSLRRVEE
NVLQQKAAGSEMSQRKQQLELELRQVTQMRSEESVKYKQSLDDAAKTIQDKNREIERLKQ
LVESETKERECLQDANTKLQRVQYDLQKAHSSAVESVSKLKVQEQELTRLRIDYERVSQE
RTVKDQDISRFQNSLKDLQLQKQRVEEELNRLKRTASEESSKRKKLEDELEGMRRSLKEQ
AIKVTNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVRDKQKTQEELRRLALELEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADCDKNATINDLRSQLQVSNTRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNWAKATMESESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAMRKIESEREKSEREKNSMRSEIERLQAEIKR
IEERCKRKLEDSSRDTQCQLETERSRLQREIDKLRQRPYGSHRETQTEYEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLMKGKKSVEEV-TSEIQPFLRGAGAIAG---ASVS
PKEKYSLVEA-KRKKLINPESTVMLLEAQAATGGIIDPHRNEKLTVDTAIARDLIEFDDR
QQIYTAEKAIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYMQLRERCRIEPHTVLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGSIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCDQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQEAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGMGN------------SGSLGGGVSDEVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISISEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQEAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISNEEAIRKGFIDGRAAQRLQDTNSYAKI------
------------------------------------------------------------
----------------------------------------------

----------------------------------------GGAV-----------AV--A
-YVQDINND-------------------PTTYLCCFLLYQN-GTCTVTRRQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGVQIRGNRDLEECFA--QANDQMDILDGLIRELRQMNQ
PCEMYQKRLLQLQEQMRALYKAISVPRARRASSKGGGCYSSQSGSGWDEYTKRVTSECLN
WMRQQKAEMELVKWGFDAASIEQQIS-DHRRTHNAIGDYRWHLDKVKTDLREKAAVHQLE
EEYEGLLKYSFERMDQLRQFQNLIQATSREIMWINDCEEEELLYDWSDRNTDISRKQEAF
SKRMSELELKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQATESYLKNLQDSIRKKFICDKSMSLQSLLEQIKELENERERILEYK
RQVQSLVNKSKKIVQLKPRNPDYRSNKPIILKALCDYKQDLKTVRKGDECILKDNNERSK
WLVTGPGGVDMLVPSVSLIIPPPNPLAVDLATKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRKEDYQKIITDLEIHYQEFLRNSQGSEMFGDEDKRKIQT
QFTDAQKHYQTLIIQLPNQPRPPQ---------T-------------------VNERNRE
HDKQEAWLLMELQKLRRQIEASEIRMVQRAPLGVDQGALHDFSVRIQDLE-GVQNDSQIM
A--ETLNKHKDLLPNFRGCEKYVYLQSEINALFQKLENINGVSAGYLDSLNALRCLLQLI
LQTEDVIRVFEVRLSEEETVPLDLDKVEAYRACLKKMKSDLNMKKSLLNTLENELQKMIQ
IHSQSCQSYTLYDMDVGKFTDKVTQLID---RWQRAEKQIDNRSWDLERQIKQLKTYRD-
LYQALCKWICDAKRRQDSIESTKLCDSNTIMRYLHDQKNLHSEICGKRDKVEELLKHADQ
CSAAIKDYELQVASYSSGLETLLNIPIKKCVVQSPAVLILQEASEAQARYIELLTRSGDY
YKFLSEMLKSMEDLKMKATKIELLEEELRLARDSNSETNNKHKFLEQNLQKYQMDISQLK
AKLMSLEEMKRQAEMDGNSAKQNLDKCYAQIKDLNDRITRLTYETEDEKRKRKLLEDRYE
QQKNDYDQLQKTRQNEKDSLGWQKLESEKVIKEKEYEIERLRVLLQD-----EGTRKREY
ENELAKVRNQFSEEMSNLKNKYETEINIKKTTIQQIAAQKDDDAKGLRAQVDRLSRENRD
LKDEIVRLNDAILQTTDQRRRAEEDALQQKACSSEVSQQKHQLELELKQIIQLRGEDNSR
YKQALEEAAATIQDKTKELERLKLQLQEEAKSRWELENELAKVRNSYDEEIISLKNKYET
EINITKTTIHQVTMQKEEDTNNYRTQLDNAVRENRNLCEEIRRLKNTITQTTDNLRKIEE
NAQQQKAAGSELSQKKQQLEIELKQVIQRHSDESMRYKQSLDDASKTIKERNKEIERLRK
LLDVETSQRKELEDENNQLKRVQFDLQKANTSATETINKLRIQEQDLARLKIDYERVLQE
KKGRDQESAKLQSTIKDLQIQKHKLEEELCRQNKNVMEETARRKKLDEEVEGMRRSLREQ
SVKITNLTQQIEEVSIVKKRNEDDLRHQREVLDGHVREKQRYMEEIRKYTSDLETLRRQL
VQEQEQLKQAHLRNEHLQKTSEEKSKNLNECKIEIERLQSLTENLTKEHLLLEEELRNVR
LEYDDLKMVRSEVD-EKNSAIAELKNQLQTSSKQTLELQGLINDLQKEREKLRQEIEKFQ
KQALEASNRIQESKNQYNHIMQERETLLIKMSALEQDKARLQRLEEELNRLKVNLESESR
LKQRLENEKQQILNDLNQWKSQHSRTEESIRKIQCEREKSEREKNTLRSEIERLQMEIKR
IEERYRCRLEETAVKNQSELESERLRLQREIEKLKQRPYGSHRSTQTEEDFCIDASKLLF
NGLRKKITAMQLYECQLIDKLTLDKLLKGQRSVEEV-AADIEPFLKGAGAIAG---VSVL
PRQKYSFVEA-KRNQLLTAENAVLLLEAQAATGGVIDPHRNEVLTVDSAIARDLI DFDDR
EQIYTAEKAITGFKDPFSGKTVPLSEAIKKNLVDREIGM RLLEAQLAVGGIVDPVNSVFL
PKDVALSRGLIDKDLYRI LNNCQSTTKNFIDPSTKKAVTYMQLKEKCRIEPHTGLLLLPV
QKRSMSFQGIRQPVSADALLEAGIIKESTRNDLERGAITVEEVSERIID FLQGSSCIAGI
YNEATKEKLGIYQAMKIGLVRPGTALELLEAQAATGFIVDPVSNARLPVEEAYKRGLVGIEFKEKLLSAERAVTGYKDPETGNIISLFQAMNKELIERGHGIRLLEAQIATGGIIDPKESYRLPVETAYKRGYFNEELNLILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDDATGLCLLPLREKKKVVHTSQKNTLRKRRVVIVDPETNREMSVQEAYSKGLIDFDTYTELAEQ---------ECEWEEITITGSDGSSRVVLVDRKTGSQYDIQDAIDKGLVEKK-FFDQYRSGSLSLTQFADMISCRNGTDEVFRH-----------------------ESVTRSPTVLSVRSSSSLIR--SGSFSETPEECSPIAAIFDTENLEKISISEAIQRGIVDSITGQRLLEAQACTGGIICPTTGQRLSLQEATSQGIIDQDMATRLKPAQKAFIGFEGIKSGRKRMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEARGRISIEEAIRNSLIDGRAAQKLQDTNSYPKILTCPKTKLKISYKDAMNRSMVEDITGLKLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------GSRSGSRSGSRRGSFDASATSSYS-YSYST----FSSGSIGR---LLEAQAATGFIVDPVSNARLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYKDPETGNIISLFQAMNKELIERGHGI RLLEAQIATGGIIDPKES
YRLPVETAYKRGYFNEELNLIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDDATGLCL
LPLREKKKVVHTSQKNTLRKRRVV IVDPETNREMSVQEAYSKGLIDFDTYTE LAEQ----
-----ECEWEEITITGSDGSSRVVLVDRKTGSQYDIQDAIDKGLVEKK-FFDQYRSGSLS
LTQFADMISCRNGTDEVFRH-----------------------ESVTRSPTVLSVRSSSS
LIR--SGSFSETPEECSPIAAIFDTENLEKISISEAIQRGIVDSITGQ RLLEAQACTGGI
ICPTTGQRLSLQEATSQGIIDQDMATR LKPAQKAFIGFEGIKSGRKRMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEARGRISIEEAIRNSLIDGRAAQKLQDTNSYPKILTCPKT
KLKISYKDAMNRSMVEDITGLKLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------
GSRSGSRSGSRRGSFDASATSSYS-YSYST----FSSGSIGR----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTS------GGGGTSRMYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDECF--AQANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNSIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGYPQHQ----------TVTTTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFALFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHCQTSQQYPLYDLDLGKFGEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGTRKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAQLRNEHFQKVIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVDEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKFISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDR
QQIYT AEKAITGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SLGSGVSDDVFSSSRHE-SVSKISTISSIRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGLELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SLGSGVSDDVFSSSRHE-SVSKISTISSIR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

------------------------------------------------------------
----------------------------------------QTGTMPRHQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANEQMEVTDSLLREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECVG
WMRQQRAEMDMMAWGVDLASVEQNVN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSSKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVELSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHVGSCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEGRMTLKNLLLTDQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCAVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQGFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKVAEL
CANSIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXEEAKRRWKYENELGKVRNSYDEQIISLKNQFET
EINITKTSIHQLTMQKEEDTSGYRAQIDQLTRENRSLSEEVKRLKSTLTQTSDSLRRVED
SMQQQKASGSEMAQRKQQLEAELRQVTQMRTEEGLRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETKERKCLEDENAKLQRVQYDLQKANSSATETIGKLKVQEQELTRLRLDYERVAQE
RATKDQDLARFQGSLKELQVQKQKVEEELSWLKRTASEDSSKRKKLEEELEGMRRSLKEQ
ATRISSLTQQLEQASVVKKRSEDDLRQQRDVLEGHLREKQRTQEDLRRLSAEVESLRRQL
LQEQESVKQAHLRNEHFQKAVEEKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNTRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTHVVQERESLLVKIKVLEQDKARLQRLEEELSRAKATLEAEAR
LKQRLETEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIRR
IEERCRRKLEDSSRETQSQLETERSRLQ-EIEKLQQRPYGSHRETQTECEWT-DSSKLVF
DDLRR-VTAMQLYEQLDRRRD---KLLXXXXXXXXX-XXXXXXXXXXXXXXXX---XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXKTVPVSEAIKKNLIDRETGMRLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLNDP RDSQKNFVDPVTKKKVSYMQLRERCRVEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERI KDFLQGSSCIAGI
YNEATKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKG-G MRLLEAQIAT-GIIDPKES
HRLTVDMAYKRGYFNEELSEILSDP SDDTKGFYDLNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQ KNTLRKRRVVIVDPETSKEMSVQEAYKKGLIDYDTFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVERK-FFDQYRSGSLS
LTQFADMISLKNGASG------------GAGLAGSISDDVFSSSRHE-SVSKISTVSSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYSYS-YSF-----SSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTS------GGGGTSRIYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRDLDECF--AQANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAQMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQIMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDTLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSVTESINKLKVQEQELTRLRIDYERVSQE
KTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSCEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVN SVFY
--------------LYRSLNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTGS------------SMGSGVSDDVFSSTRHE-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTGS------------SMGSGVSDDVFSSTRHE-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

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--------MS-GPKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVN N---
------------------------SQKNFVDPVTKKKVSYMQLRDRL-------------
--------------TVTELVDSGILRPST-------------VGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLVDKK-FFDQYRSGSLSLTQFADMISLKNGVGSSI------------SMGGSISDDVFSSSRHE-SVNKISTISSIRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEAIDRGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVAQGLIDQDMSTRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEMHGRISTEEAIRRGFIDGRAAQRLQDTSTYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLVDKK-FFDQYRSGSLS
LTQFADMISLKNGVGSSI------------SMGGSISDDVFSSSRHE-SVNKISTISSIR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEAIDRGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVAQGLIDQDMSTR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEMHGRISTEEAIRRGFIDGRAAQRLQDTSTYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTS------GGGGTSRMYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDECFA--QANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNSIGDYRWQLDKIKADLVLF-------
------CKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGYPQHQ----------TVTTTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLASFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFGEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAEIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNDRKCLEDENARLQRVQYDLQKANSS------------QELTRLRIDYERVSQE
RTVKDQDITRLLQE-----------------------------EEAGGELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNAVGTSS------------SMGGGVSDDVFSSSRHE-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSTYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNAVGTSS------------SMGGGVSDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSTYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRCEMTYGGGGG-------------GSN---NK
MFY--MRRC-------------------TVNEQNSDGYCQTGGTMSRHQNQNTIQDLLQN
CADCLMRAELIVQPELKY--GDGIQLGRSRELDEYFA--QANEQMEITDSLIREMRQMGQ
PCDAYQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXAEMDLVQWGVDSASVEQHIN-SHRVIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLVKASFERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSYKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKYYQTLVIQLPGHHQHQ----------TVTTTEITHLGKDP----NQIVIEIRE
NDKQETWILMELQKIRRQMEHCESRMTLKNILQADQGSSHHITVKINELK-AVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSVRGLLQAI
LQTEDMLKVYESRLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKALQ
IHSQTSQQYPLYDLDLGKFSDKVNQLSD---RWQRIDKQIDFRLWDLEKQIKQLKNYRD-
NYQAFCKWIYDAKRX-XXLESMKFE-SSTVMKYLNEQKNLHNEISGKRDKSEEVQKIAEL
CSNSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAAEIHARYIELLTRSGDY
YRFLSEMLKSLDDLKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXX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-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX---XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDFLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYKDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCMKDEETGLCL
LPLKEKKKPIQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFVELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGNQYDIQDAIDKGLVDRK-FFAQHRSGSLS
LTQFADMISLKNGNSN------------I--GSGSGGDEVFSSSRHE-SVSKTSSISSIR
NLTIRSSSWSDTLEE -SPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGI
INPTT-------------------------------------------------------
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--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTY---GGGGGGGGG-GGGGGG----NSR
MYY--SRRYTVNDQN-------------------SDGYCQT-GTISRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVSWGVDLASVEQHIA-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQRLLDQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSSKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLAGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHVGSCQDVNHNKVIEANRE
NDKQETWMLIELQKIRRQMELCEGRMALKNILLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCAVRALLQAI
LQTEDMLKVYEARLTEEETVYLDLDKVEAYRCGLKKIKTDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADMHSRYIELITRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQTECSQFK
AKLVSLEELKRQAELDGKAAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKAVEDRFD
QQKSDYDQLQKARQCEKESLGWQKIESEKAIKDKEFEIERLRILLQE-----ESARKREY
ENELAKVRNHYNEEMSNLRNKFETEINITKTTIQEISMQKEDDSKNLRNQLDRLTRENRD
LKDEIVRLNDSILQTTEQRRRAEEDALQQKACGSETMQKKQQLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKADFQDEAKRRWEYENELAKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMKREEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
NVQQQKATGSEMSQRKQQLEIELRQVTQMRTEESLRYKQSLDDAAKTIQDKNKEIERLKQ
LIETETNERQFLKDENAKLQRAQFDLQKANDSATETISKLKVHEKELTRLRIDYERISQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELMRLKRTASEDSCKRKQLEEELEGMRRSLKEQ
AIKITSLTQQLEQVSIIKKRSEEDLRQQRDVLDGHVRDKQRTQEELRRLASEVEALRRQL
LQEQENVKQAHVRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLK
LEYDELRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIHESKSQCTQVVQERESLLVKIKVLEQDKIRLXR-----------------
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRDTQSQLETERCRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASVS
PKEKYSLVEA-KRKNLITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDR
QQIYTA EKAITGFDDPFSGKTVSLSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLNDP RDSQKNFVDPVTQKKVSYMQLRERCRIEPHTGLLFLSV
QKRSMSFQGIRQPVTVSELVDSGILGLSTVNELESGRISYDEVGERI KDFLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLTVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILSDP TDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFEQYRSGSLS
LTQFADMISLKNGVGNSS---------GMG--G-SVSDEVFSSSRHE-SVSKISTISSVR
NLTIKSSSLSDPLEESSPIAAIFDIENLEKISIAEGIERGIVDSITG QRLLEAQACTGGI
IHPTSGQKLSLQDAISQGLVDQEMATRLKPA QKAFIGFEGVKG-K-KMSAAEAVKEKWLP
YEAG QRFMEFQYLTGGLVDPEVHGRISVEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDVTGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYT-YS-SY---AFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTY---SGGGGGGGGGG--GGG----TSR
TFYSHSRRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQEMLQN
CSDCLMRAELIAQPELKF--GEGMQLAWNRELDEYFT--QANDQMEIIDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGAGGYTCQSGSGWDEFTKRLTGECLG
WMRQQREEMDLMAWGVDAGSVEQHIN-SHRSIHNTIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKIIEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHLGTCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEARMTLKNLLLAEQGSTHHITVKINELK-SVQNDSQAL
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVSDGYLNSLCSVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFTEKVTQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQMDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSETMQKKQRLEIELKQIIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEVKRLKNTLAQTTENLRRVEE
NAQQQKATGSEMSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LVDKETNERKCLEDENSKLQRVQYDLQKANNSASEAMSKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQ
AVKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKVRLQRLEDELNRAKATLEAESR
VKQRLESEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLESERCRLQKEIEKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLSVDNAVARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GLG---GSVNDDVFSSSRHD-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVNQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGGY--LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYDTFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GLG---GSVNDDVFSSSRHD-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVNQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGGY---

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTY---SGGGGGGGGGG--GGG----TSR
TFYSHSRRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQEMLQN
CSDCLMRAELIAQPELKF--GEGMQLAWNRELDEYFT--QANDQMEIIDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGAGGYTCQSGSGWDEFTKRLTGECLG
WMRQQREEMDLMAWGVDAGSVEQHIN-SHRSIHNTIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKIIEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHLGTCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEARMTLKNLLLAEQGSTHHITVKINELK-SVQNDSQAL
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVSDGYLNSLCSVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFTEKVTQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLSWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQMDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSETMQKKQRLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEVKRLKNTLAQTTENLRRVEE
NAQQQKATGSEMSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LVDKETNERKCLEDENSKLQRVQYDLQKANNSATEAMSKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQ
AVKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLESERCRLQKEIEKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAVARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GLG---GSVNDDVFSSSRHD-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVNQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGGY--LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYDTFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GLG---GSVNDDVFSSSRHD-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVNQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGGY---

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--------------QLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFR
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRKRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQRLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDTKGLRNQIDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEENAIQQKACGSEIMQKKQQLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQ-----------------------------------------------
------------------------------------------------------------
-------------------------------------------------DKNKELERLKQ
LIEIETNQRKCLEDENAKLQRTQYDLQKANSNATETISKLKIHEQELTRLKIDYERISQE
RTIKDQDISRFQSSLKDLQFQKQKVEDELNRLKKTASDECSKRKKLEDELESMRRSLKEQ
AIKITNLTQQLEQTSISKKRSEDELRQQRDVLDGHVREKQRTQEELRKLASEVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQCLTENLTKEHLMLEEELRNLR
LEYDELRRGRSEADSDKNAAISDLRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQAIEASNRIHESKTQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLESEMR
VKQRLECEKQQIQNDLNQWKSQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEDRCRRKLEDSTRETQSQMESERCRMQREIDKLKQRPYGSHRETQTEEEWSIDPSKLMF
DGLRKKVTAMQLYECQLIDKTTLDKLLR--------------------------------
------------------------------------------------------------
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-----------------------------------GQISYDEVGERIKDFLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYKDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCMKDEETGLCLLPLKEKKKPIQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKCLIDYDTFVELSEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFEQYRSGSLSLTQFADMISLRNGSSN-------------ISGGSSNGDDVFSSSRHE-SVSKTSSISTIRNLTIRSSSWSDPLEETSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIINPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISSEEAIRKGFIDGRAAQKLHDTNNYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGS--------RSGSRSGSRRGSFDASGNSSYS-YSYTF-----SSSS--LELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYKDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCMKDEETGLCL
LPLKEKKKPIQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKCLIDYDTFVELSEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFEQYRSGSLS
LTQFADMISLRNGSSN-------------ISGGSSNGDDVFSSSRHE-SVSKTSSISTIR
NLTIRSSSWSDPLEETSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
INPTTGQKLSLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISSEEAIRKGFIDGRAAQKLHDTNNYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGS------
--RSGSRSGSRRGSFDASGNSSYS-YSYTF-----SSSS-------

------------------------------------------------------------
--------------------------------------------MSRMQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEVTDSLIREMRHMGQ
PCDVYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSLHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKTSFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLSQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIIQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNPNKMIETNRE
NDKQETWLLMELQKVRRQIEHCEGRMTLKNLLLTDQPSTHHITVKINELK-SVQNDSQAL
A--EVLNQLKDVLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLFTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKAELQKAQQ
IHCQTSQQYPLYDLDLGKFNDKVIQLTD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQNFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLSSLEELKRQAELDGKSAKQNLDKCYAQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKSDYDQLQKARQSEKESLGWQKLESEKAVKEKEYEIERLKVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKHSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNSYDEEIISLRNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEIKRLKNTLAQTTENLKRVEE
NIQQQKATGSEMSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNRELERLKQ
LVEKESSARKCLEGENARLERVQYDLQKANSSVTETISKLKGQEQELTRLRIDYERVSQE
RNVKDQDIARFQSSLKELQLQKQKVEEELSRLKRTACEDSSKRKKLEEELEGMRRSLKDQ
AIKITSLTQQLEQVSIVKKKSEDDLRQQREVLDGHLRDKQRTQEDLRRLSSEVEALRRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEEDNDKNAAICELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIHESKSQCTQVVQERESLLVKIRVLEQEKVRLQRLEEDLNRLKATLEAEGR
VKQRLESEKQQIQNDLNQWKTQYSRKEEAMRKIESDREKSEREKNTLRSEIERLQAEIKR
IEERCRQKLEDSSRETQSQLETERSRLQREFDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGVIDPHRNEKLTVDNAIARDLI DFDDR
QQIYMAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGIVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPFTKKKVSYVQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVNIAYKRGYFNEELSEILTDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQXXXXXXXXXXCEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFDQYRSGSLSLTQFADMISLKNGVGSSI------------SMGSGVSDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISVSEAIDRGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAMAQGLIDSDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVNIAYKRGYFNEELSEI LTDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQXXXX
XXXXXXCEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDKK-FFDQYRSGSLS
LTQFADMISLKNGVGSSI------------SMGSGVSDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISVSEAIDRGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAMAQGLIDSDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTS------GGGGTNRIYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDECFA--QANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRVSDFSVAWGLNL------------------------------------------
------LKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSVLHPER-----------------------
ECFLG-------------------------------------------------------
------------------------------------------------------------
-----------------------------SIPS---------------------------
--------------DFLGD--------SL----------------------------LHI
LGTNKMILL---------------------------------------------------
-------------------------------------YLFLPRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQITQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQCDLQKANSSATESINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSCEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLETETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTGS------------SMGSGVSDDVFSSTRHE-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSASRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTGS------------SMGSGVSDDVFSSTRHE-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSASRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

------------------------------------------------------------
--------------------------------------------MSRHQNQNTIQEMLQD
CADCLMRAKLIVQPELKY--GDGVQLGRNRELDECFA--QANEQMEITDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKTMSAPRARRSSSKG--GYTCQSGSGWDEFTKRLTGECLG
WMRQQRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX--XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXIQLPGHPQHQ----------TVTTTEITHLGACQDVNHNKVLEANRE
SDKQEAWLLLELQKVRRQMEHCEGRTALRSTLLADQSSCHHITVKINELKXXXXXXXXXX
XXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTVRLLQAH
LQTEDMLKVYEAQLTEEETVCLDLDKVEAYRCRLKKIKSDLNLKKSLLAAMKTELQKAQQ
THAQASQQYPLYDLDLGKFAEKVTVLTD---RWGRIDKQIDFXXXXXEKQIKQLRNYRVY
NYQSFCKWLYDAKRRQDALESMKFGDTNTVVRFLNEQKALHNEICGKRDKSEEVQKVAEL
CANSIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXMKNTKIEVLEEELRLMRDANSENCNKNKFLDQNLQKY-AECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTFEVEDEKRRRKVVEDRFD
QQKSDYDQLQKARQSEKESLGWQKLESEKTIKEKEYEIERLRALLQE-----EGARKREY
ESELAKVRSRYNEEMSNLRNKYETEISISKTTIKEISLQKEDDAKALRGQLDQLCRENLG
LKDEIVRLNDSILQSSEQRRRAEEQALQQRACGSELAQRQQQLEAELKQLTQQRAQDNAR
HKQSLEEAARTIQDKNKEIERLRAEFQDEARRRREHERELAQVRSSHDEEIISLRNQFEA
EINVTKTTLHQLSLQKDEDTSGFRARIDGLTRENRGLAEEVQRLKATLAQSSEALRRAEE
STQQHRASGSEQAQRRQQLEAELRQVAQMRAEEGARYKQSLDEAARTIQDKNREIERLQQ
LVGTETQQRKGLEEENARLQRAQQELQKAQSSAAESLGRLKGQEQELARLRLDCERAAQE
RAXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXRRLRTAPRRQLEAELEALRRAAQEQ
ALKVSGLEQQLEQASAGQWRSEDDLRQQRGALDGHVREKQRLQEELRRAAGELEALQRQL
AQEQDAVRQAQARSEHLQRAIEDKSRGLNESKIEIERLQSLTESLTKEHLLLEEELRNLR
LQYDELRRGRGQADSD---AVAELRAQLQTSADRTLELQGLITELQRERANLRQEIERFQ
KQALEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIAG---ASAS
PKDKYSLVEA-KRQKLIAPEAAVMLLEAQAATGGIIDPHRNERLTVDSAVARDLIDFDDR
ERIYTA EKAVTGFDDPFSGKTVSVSEAVRKNVIDRETG LRLLEAQLASGGVVDPVNSVFL
PKDVALARGLLDRDLYRCLNDP RDGQKNFVDPVTKKKVSYLQLRERCRVEPHTGLLLLSV
QRRSMSFQGIRQPVPVSELVDSGILRPSTVNELESGQISYDEVGERI KDFLQGSSCIAGI
YNETTRQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDSVSNLRLLVEEAYKRGLVGI
EFMEKLLSAERAVTGYNDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX
XXXXXX-XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXX-XXXXXXXXXX-X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVKDKKKMAAEVKEKWLP
YEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLRDTGSYAKILTCPKT
KLKISYRDALSRCMVEDVTGLRLLEAASVSSKGLPSPYNMSSAPGSRAGSRSDSCS----
GSRSGSRAGSRRGSFDATSNSSYS-YSYS-----FSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEATC---GGGGG--------GGG----TSR
MYY--SRRCTVTDQT-------------------SDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLSRSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQRLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITH-SSCQDVNHNKVIETNRE
SDKQETWMLMELQKVRRQMELCEGRMTLKNLLLADQGSTHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVYLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSDKVTQLTD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEICGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADLHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKAVEDRFD
QQKNDYDQLQKARQCEKESLGWQKMESEKAIKEKEYEIERLRVLLQE-----EGTRKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEEDALQQKACGSEMLQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELAKVRNNYDEEIISLKNQFET
EINITKTTIHQLTRQKEEDTSGYRAQIDHLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
NAQQQKATGTEVSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LIETETSARKCLEEENAKLQRTQYELQKANNSATETISKLKVQEQELTRLRIDYERVSQE
RTVKDQDIVRFQSSLKDLQLQKQKVEEELNRLRRTASEDSSKRKKLEDELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLDGHLRDKQRTQEELRRLSSEVEALRRQL
LQEQENVKQAHLRNEHFQKAIEEKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRSRSEADSDKNTTISELRSQLQISNNRTKRVQGVINI-SRERAVLTSVITQAA
ALKFQASNRIQESKNQCTQVVQERESLLVKIKVLEQDKSRLQRLEDELTRLKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSFRSEIERLQAEIKR
IEERYRRKLEDSTRETQSQLETERSRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDR
QQIYT AEKAVTGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQQVTVSELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDDETGLCLLPLKEKKKEVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIDRK-FFDQYRSGSLSLTQFADMISLKNGIGNSG---------GIG--ASSISDDVFSNSRHE-SLSKISTISSVRNITIRSSSLSDPLEELSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTSGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSTYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNASYS-YS--Y---SFSSSSIGLELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDDETGLCL
LPLKEKKKEVQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLIDRK-FFDQYRSGSLS
LTQFADMISLKNGIGNSG---------GIG--ASSISDDVFSNSRHE-SLSKISTISSVR
NITIRSSSLSDPLEELSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTSGQKLSLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSTYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRS
GSRSGSRSGSRRGSFDATGNASYS-YS--Y---SFSSSSIGH----

------------------------------------------------------------
------------------------------------------------------------
--------------ELKY--GDGIQLARSRELDEYFA--QANDHMEIADSLVREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISAPRARRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDLVAWGVDPGSVEQHIN-SHRVIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAHSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVSLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TITTTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQMELCESRMALKNLLQADHGSSHHITVKINELK-SVQNDSQAL
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVYLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLSSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLCRENRD
LKEEIVRLNDSILQATEQRRRAEENVLQQKACGSEAMEKK-QLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKTEYQEEAKRRWEYENELGKVRNSYDEEIISLKNQFET
EINITKATIHQLTMQKEEDTSGYRAQIDTLTRENRSLTEEIKRLKNTLTQTTENLRRVEE
NAQQQKATGSEVAQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDK-KEIERLKQ
LIEKETSERKCLEDENAKLQRAQYDLQKANSCATETISKLKVQEQELVRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTASEDSSKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQATIVKKRSEDDLRQQRDVLDGHLRDKQRTQEELRRLSSEVEALRRQL
LQEQENVKQAHVRNEHFQKAIEDKSRSLNESKIEIERLQCLTENLTKEHLMLEEELRNLR
LEYDDLRKNRSEVDNDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIERFQ
KQALEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX---XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLNDP RDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELETGQISYDEVGERI KDFLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEA Q AATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVNMAYKRGYFNEELNEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQIQTSQ KNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVSN------------SSGLGGSVNDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEAHGRISMEEAIRKGFIDGRGAQRLQDTSSYAKILTCPKT
KLKISYKDAVNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRS-FDAT----------------------------

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTC---GGGGGGGGGG---GGG----TSR
MYY--SRRCTVTDQN-------------------SDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQRLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGYPQHQ----------TVTTTEITHHGSCQDVNHNKVIETNRE
HDKQETWMLMELQKIRRQMEHCEGRMSLKNILLADQGSTHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSDKVTQLTD---RWQKIDKQIDYRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVLRFLNEQKNLHNEICGKRDKSDEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKAVEDRFD
QQKNDYDQLQKARQCEKESLGWQKMESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ESELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQTTEQRRRAEEDALQQKACGSEMMQKKQHLEMELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKVEFQEEAKRRWEYENELAKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDSLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEIELRQVTQMRTEESLRYKQSLDDAAKTIQDKNKEIERLKQ
LIETETSERKRLEEENAKLQRAQYDLQKANNSATETISKLKVQEQELTRLRIDYERVSQE
RAVKDQDITRFQSSLKDLQLQKQKVEEELNRLRRTASEDSLKRKKLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLDGHLRDKQRTQEELRRLSAEVEALRRQL
LQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRSRSEADSNRNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIDKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKSRLQRLEDELTRAKATLDAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERYRRKLEDSTRETQSQLETERSRLQREIDKLKQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQQVTVSELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKEVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFRELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQEAVDKGLIDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GIG--G-GISDDVFSNSRHE-SVSKISTISSVRNITIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTSGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKEVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFRE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQEAVDKGLIDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GIG--G-GISDDVFSNSRHE-SVSKISTISSVR
NITIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTSGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRS
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC---GGVGGGGGGG--GGGG----TSR
MYY--SRRCTVTDQN-------------------SDGYGQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISGPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDMMTWGVDLASVEQHIS-SHRSIHNTIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNTPLQRLLEQIKELEKEREKILEYK
RQVQSLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSSKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIKAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQT
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHLGTCQDVNHNKVIETNRE
NDKQEAWMLIELQKIRRQMELCESRMALKNILLADQGSSHHITVKINELK-SVQNDAQAI
A--QVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCAVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRLWDLEKQIKQLRNYRD-
NYQTFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLSIPIKRTVIQSPSGVILQEAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKAVEDRFD
QQKSDYDQLQKARQNEKESLGWQKMESEKAIKEKEFEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKEEIVRLNDSILQTTEQRRRAEEDALQQKACGSEVLQKKQYLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKTEFQEEAKRRWEYENELAKVRANYDEEIISLKNQFET
EINITKTTIHQLTLQKEEDTSGYRAQIDTLTRENRSLSEEVKRLKNTLAQNTETLRRVEE
NVQQQKATGLEMSQRKQQLEVELRQVTQMRTEESARYKQSLDDAAKTIQDKNKEIDRLKQ
LIETEASQRKCLEDENARLQRAQGELQKAHSSATETISKLKVQEQELLRLRLDYERVSQE
RTVRDQDIARFQTSLKELQLQKQKAEEELARLKRAASEDSSKRKKLEEELEGMRRTLKEQ
AIKVTSLTQQLEQASIVKKRSEDELRQQRDTLDGHLREKQRTQDELRRLASEVEALRRQL
LQEQESVRQAQTRNEHFQKAIEDKSRSLNESKIEIERLQSLTESLTKEHLMLEEELRQLR
LEYDDLQRGRSEADHDKNATIAELRNQLQISNNRTLELQGLINDLQRERENLRQEIERFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEEELSRAKTTLEAESR
LKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLETERCRLQREIDRLKQRPYGSHRETQTEYEWSVDSSKLVF
DGLRKKVTAMQLYECQLIDKATLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLITPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDR
QQIYT AEKAITGFDDPFSGKTVSVSEAIKKNLIDRETG MRLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRSLND PRDSQKNFVDPVTKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVSELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLIDRK-FFEQYRSGSLSLTQFADMISLKNGVGGGVGGIV----GGGSSTGGGLSDDVFGSSRHE-TVSKISTISSIKNLTIRSSSLSEPLEESSPIAAIFDTENLEKISISEGIERGIVDSISGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVQGRISTEEAIRKGYIDGRAAQRLQDTSTYGKILTCPKTKLKISYKDAINRSMVEDVTGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YC--Y---SFSSSSIGLELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKN TLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDTIDKGLIDRK-FFEQYRSGSLS
LTQFADMISLKNGVGGGVGGIV----GGGSSTGGGLSDDVFGSSRHE-TVSKISTISSIK
NLTIRSSSLSEPLEESSPIAAIFDTENLEKISISEGIERGIVDSISG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVQGRISTEEAIRKGYIDGRAAQRLQDTSTYGKILTCPKT
KLKISYKDAINRSMVEDVTGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YC--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEVTS------GGGGTSRIYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRDLDECF--AQANDQMEILDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAQMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLVLFSAGGSGG
QEFETILKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQIMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDTLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSVTESINKLKVQEQELTRLRIDYERVSQE
KTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSCEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTGS------------SMGSGVSDDVFSSTRHE-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTGS------------SMGSGVSDDVFSSTRHE-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTS------GGGGTSRIYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGMQLTRSRDLDECF--AQANDQMEILDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSATESINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSVKDLQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSCEVEALRRQL
LQEQDSVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRNQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

------------------------------------------------------------
---------------------------------------QT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELRY--GDGLQLARSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISSPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGDCLG
WMRQQRGEMDMVTWGADLSWVEQHIN-SHRSLHNVIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKTSFERMDHLRQLQSIIQATSKEIMWINDCEEEELLYDWSDRNTDIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTETYLKGLQDSIRKKFSCDKNMPLQRLLDQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVVLIIPPPNPLAVDLSCKYKRYFLLLKRTYNGLYLSLQCHLSWWL
FDFLNIRSLRFICVVSWLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKYYQTLVIQLPGHPQHQ----------TVTTTEVTHLGSCQDVNHNKVIEINRE
NDKQEAWILMELQKIRRQMEHCEGRMTLKNLLLTDQGSSHHITVKINELK-SVQNDSQTI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRSLLQAI
LQTEDMLKVYEARLTEEETVYLDLDKVEAYRCGLKKIKNDLNLKKTLLATMKTELQKAQQ
IHNQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDYRIWDLEKQIKQLRNYRD-
NYQAFCKWLCDAKRRQDSLESMKFSDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CGNSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRMARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKVVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EANRKREY
ESELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISLQKEDDSKNLRNQLDRLSRENRD
LKEEIVRLNDSILQTTEQRRRAEENALQQKACGSEILQQKQHLEIELKQIINQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKTEFQEEAKRRWEYENELAKVRSSYDEEIISLKNQFET
EINITKTTIQQLTVQKEEDTSGYRVQVDTLTRENRNLAEEIKRLKSTLAQSTESLRRAEE
NVQQQKTTGSEMSQRKQQLEIELRQVTQMRTEESVRYKQSLDDAAKTIQEKNKEIDRLKQ
LIETETKERKCLQDENAKLQRVQYDLQKANSSATETISKLKVHEQELLRLRVDYERVSQE
RTTKDQDIIRFQGSLKDLQLQKQKAEEELTRLKRTASEDSSKRKKLEDELEGMRKSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLEIEALGRQL
LQEQENVKQAHLRSEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDELRRSRSEADSEKNSTIGELRSQLQISNNRTLELQGLINELQRERENLRQEIEKFQ
KQAIEASNRIQESKTQCTQVVQERESLLMKIKVMEQDKVRLQRLEDELNRAKATLETESR
LKQRLESEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRCEIERLQAEIKR
IEERCRRKLEDSTRDTQSQLETERSRLQREIDRLKQRPYGSHRETQTEYEWTVDPSKLVF
DGLRNSSHVKHITGCSLATLISMNKLILLESFSNFVMCFFLKPILLIHNSLTFHKSCRFN
FFIKLPSITN-FRKKLITPESTVMLLEAQAATGGVIDPHRNEKLTVDSAIARDLIDFDDR
QQIYT AEKSITGFDDPFSGKTVSISEAIKKNLIDRETG MRLLEAQIASGGVVDPV-SVFL
PKDVALARGLIDKDLYRSLND PRDSQKNFVDPVTKKKVSYLQLRERCRIEAH-GLLLLTV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVTELESGKISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILTDPSDDTKGFFDPNTEENLTYLQLKERCIKDDETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNREMSVQEAYKKGLIDYDTFRELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDRGLVDRK-FFDQYRSGSLSLTQFADMISLKNGAGS-------------GGMGAGLTDDVFSSSRHE-SVSKISSVSSVRNVTIRSSSLSDSLEESSPIAAIFDTENLEKISISEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFVGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYITGGLVDPEVHGRISTEEAIRKGFIDGRGAQRLQDISSYAKILTCPKTKLKISYKDALSRSMVEDITGLRLLEAASTSSKGLPSPYNISSAPGSRSGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYS-YS--Y---TFSSSSIGLELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYNDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEILTDP SDDTKGFFDPNTEENLTYLQLKERCIKDDETGLCL
LPLKEKKKQVQTSQKN TLRKRRVVIVDPETNREMSVQEAYKKGLIDYDTFRELCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDRGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGAGS-------------GGMGAGLTDDVFSSSRHE-SVSKISSVSSVR
NVTIRSSSLSDSLEESSPIAAIFDTENLEKISISEGIERGIVDSITG QRLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATRLKPA QKAFVGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYITGGLVDPEVHGRISTEEAIRKGFIDGRGAQRLQDISSYAKILTCPKT
KLKISYKDALSRSMVEDITGLRLLEAASTSSKGLPSPYNISSAPGSRSGSRSGSRSGSRS
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---TFSSSSIGH----

--MSCNGGSHPRINTLGRLTRAESGPDLRYEVTC---GGGGGGGTSRMYYS---------
------RRG-------------------VITDQNPDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDEYFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPHHQ----------TVTTTEITHVGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLTSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDSLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
DVQQHKATGSEVSQRKQQLEVELRQVTQMRTEESLRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSVLETTNKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTVSEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKTQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLISAESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVNIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKRQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGG--------------SMGSGVSDDVFSSSRHE-SVSKLSTISNVRNLTIRSSSFSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIINPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAYIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTNSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVNIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKRQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGG--------------SMGSGVSDDVFSSSRHE-SVSKLSTISNVR
NLTIRSSSFSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
INPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAYIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTNSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

------------------------------------------------------------
----------------------------------------QTGTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLAQSRELDECFA--QANEQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTSECLG
WMRQQRAEMDLMAWGVDLASVEQSIH-SHRSIHNTIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKDLQDSIRKKYPCDKSTPLQRLLGQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCLIDIEKIRAM-TIAKLKTMRQEDYMKTISDLELHYQEFIRNSQGSEMFGDDDKRKMQT
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTTTEITHLGSCQDVNRNKVIETNRE
SDKQETWMLIELQKIRRQMEHCEGRMSLKNLFLADQGSSHHITVKINELK-SVQADAQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKSDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGNSTTLXXXXXXXXXXXXXXXXXXXXXLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLKSMKFVYSNTVMRFFELFKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGXXXXXXXXXXXXXXXXXXXXXXXXAADMHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKYLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELN-KITRLTYEIEDEKRRR-KVEDRFD
QQSD-Y-DLQKARQSEKESLGWXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXLTPQLEQASIGKKKSEDD-RQQRDVLEGHLREKQRTQDELRRLASEVEALRRQL
LQEQDNVKQAHVRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDVRRGHSEADSGKNATISELRSQLQISNSRTLELQGLINDLQRERENLRQEIERFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKTRLQRLEDELNRAKVALEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQMETERCRLQKEIDRLKQRPYGSHRETQTEYEWSVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEXXXXXXXXXXXXX---XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
-----XXXXXXXXXXXXXXXXXXXXXXRKTGIQYNIQDTIDKGFIDRK-FFDQYRSGSVS
LTQFADMISLKNGVGG------------SSAEGGSISDDVFSSSRHE-SVNKISTISSIR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGI
IHPTTGQRLSLQDAASQGLIDQDMATRLKPA QKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISTEEGHQKGFID-RAAQRMQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNVSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYSY---------------------

--MSMNGGSHPRINTLGRMVRAESGPDMRFEANSHTVGGGGTSG-----------HTTHK
MYYVQ--KN-------------------YGQDLSSDGYCQN-GTCTMSRRQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQISRNRELEECFA--QTNDQMDILDGLIREMRQMGQ
PCDLYQKRLLQLQEQMRALYKAISGPRVRRASSKGGG-YSSQSGSGWDEYTKRITGECVG
WMRQQKADMELVKWGFEAAAIEQQIN-DHRKFHNAIGDYRWHLDKVKTDLREKAAVHQLE
EEYETLLKFSFERMDQLRQFQNLIQATSREIMWINDCEEEELLYDWSDKNTDIARKQEAF
SKRMSQLELKEKELNKLKQESDQLVLSQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTENYLKNLQDSIRKKYICDKNMSLQNLLDQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDHRSNKPIILKALCDYKQDLKTVRKGDECILKDNTERSK
WLVTGPGGVDMLVPSVSLIIPPPNPFAVGLATKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRSM-TIAKLKTMRREDYQKIITDLEIHYQEFLRNSQGSEMFGEDDKRKIQT
QFTDAQKLYQTLVIQLPNQQRPQQQQQQQ-QQHTVVATEV-----T---QLASVNERNRE
LEKQEAWLLTELQKIRRQIEICEMRMVQRTPLRVDQGASHNFSVKINELQ-GIQNDSQTM
S--DTLNKHKDYLPNFRGSEKYVYLQLEMNNLFQRLENINGVSAGYLDSLNALRSLLQVI
LQTEDMIKVFEVRLTEEETVALDLDKLEAYRACLKKMKTDLNQKKALLNTLETELQNAMQ
IHSQSSQAYVLYDLDLGKYTDKVSQITD---RWQRVEKQIDHRSWDLERQVKQLKTYRD-
LYQALNKWICEAKRKQDTIEAVKLGDCNTIIRYSQEQKNLHSEITGKRDKVEEVLKQADL
CAAAIKDYELQAASYSSGLETLLCIPIKRTIVKSPAGLILQEASDIQSRYIELLTRSGDY
FKFLSEILKSMEDLKMKTTKIEMLEEELRLSRDANSDNSNKHKFLEQNLQKFQMECSQLK
TKLTSLEELKRQAEMDGNSTKQNLDKCYAQIKDLNDRITRLTYEIEDEKRKRKQMEDRYE
QQKNENDQLQKTRQNEKDSLSWQKIESEKVIKEKEYEVEKLRMLLQD-----EGARKREY
ENELAKVRNQFKEEMSNLKNKYETEINIKTTTIHQLSSQKEDDAKSLRNQLDRLARENRD
LKDEIVRLNDAILQATEQRRRAEENALQQKACGSEVSQQKQQLELELKQIIQVRNEDNTR
YKQALEEASSTIQEKNKEIEKLKIQLQEETKSQWQLENELAKVRNNFDEEIINLKSKYET
EINITKTTIHQITVQKEEDTNSYRTQLDNAMRENRNLCEEIRRLKNTISQTTENLRKIEE
NAQQQKATSSEISQKKQQLEVELKQVIQMHSEESMRYKQSLDDATRTIQERNKEIERLRK
SFEVETSKRKDVEEEKKQLQRVQFDLQKANASATETINKLRIQEQELTRLKIEYERISQE
KKGKDHESAKFQSTVKDLQLQKRKLEEELGRLNKSATEESSKRKKVEEELESMRRSFREQ
SVRINSLTQQIEEVSIVKKRSEDDLRHQREALDSHLREKQRCVEEIRKYTSEIETLSHQL
VQEQEHLKQAHLRNEHLQKAIEDKSRSLNECKIEIERFQSLTENLTKEHLMLEEELRNLR
LEYDDLRMGKSEADSEKNATIVELKNQLKTSSKQTLELQGLINDLQRERENLRQEIEKFQ
KQAREASTRIQESQSQYTHIMQERETLLIKISTLEQDKARLQRLEEELNRAKVTLETESR
LKQRLESEKQQILNDLNQWKSQYSRKEESIRKIESEREKSEREKNALRSEIERLQMEIKR
IEERYKCRLEELSCKSQSEMEAERLRLQREIEKLKHRPCGSHRCTQTEEDFAIDPSKLLF
NGLRKKITAIQLYECQLIDKSTLDKLLRGQKSVEEV-AADIEPYLKGAGAIAG---ASPT
PKEKYTLLEA-KRKQLLTPENTVLLLEAQAATGGVIDPHRNELLTVDSALARDLVDFDDR
EQIYT AEKAITGFKDPFSGKTVPVSDAIKKNLIDRETG IRLLEAQMTAGGIVDPVNSVFL
PKDVALSRGLIDQDLYRVLNN PHNASKSFIDPATKKAISYMQLREKCRIEPHTGLLLLPV
HKRGMSFQGLRRPVLVSELVSSGIIQESTANDLETGAISVEEVNDKIKD FLQGSSCIAGI
YNEATKEKLGIYQAMKIGLVRPGTALELLEAQAATGFMVDPVSNMRLPVEEAYKRGLVGIEFKDKLLSAERAVTGYKDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVHMAFSRGYFNEELSMILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEATGLCLLPLRDKKKMVQTSQKNTLRKRRVVIVDPDTNREMSVQEAYSKDLIDYNTYLELSEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFEQYRSGSLSLTQFADMISLKNGGDEVFRH-----------------------ESVTKAPTVLSVRSS-SVRK--SGSFSSPLEECSPIAAIFDTENLERISISEAMQRGIVDTITGQRLLEAQACTGGIMCPTTGQRLSLQDAVTQGIIDHDMATRLKPAQKAFLGFEGLKG-KTKMSAAEAMKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISMEEAIRKGLIDGRSAQRLQDTNNYTKILTCPKTKLKISYKDAMSRSMVEDITGLRLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------GSRSGSQSGSRRGSFDASTSSSYS-YSCSA----FSSSSIGLELLEAQAATGFMVDPVSNMRLPVEEAYKRGLVGI
EFKDKLLSA ERAVTGYKDPETGNIISLFQAMNKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVHMAFSRGYFNEELSMILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDEATGLCL
LPLRDKKKMVQTSQKN TLRKRRVVIVDPDTNREMSVQEAYSKDLIDYNTYLELSEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFEQYRSGSLS
LTQFADMISLKNGGDEVFRH-----------------------ESVTKAPTVLSVRSS-S
VRK--SGSFSSPLEECSPIAAIFDTENLERISISEAMQRGIVDTITG QRLLEAQACTGGI
MCPTTGQRLSLQDAVTQGIIDHDMATRLKPA QKAFLGFEGLKG-KTKMSAAEAMKEKWLP
YEAG QRFLEFQYLTGGLVDPEVHGRISMEEAIRKGLIDGRSAQRLQDTNNYTKILTCPKT
KLKISYKDAMSRSMVEDITGLRLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------
GSRSGSQSGSRRGSFDASTSSSYS-YSCSA----FSSSSIGR----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEATC---GGGGGGGG-GG-GGCT----TTR
TYY--SRRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CADCLMRAELIVQPELKY--GDGIQLARSRELDEYFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKLSFERMDHLRQLQSIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEAKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENATYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGACQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEGRMSLRNLLLTDQASTHHITVKINELK-SIQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVSDGYLNSLCSVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFNEKVIQLSD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYAQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRNLAEEIKRLKSTLAQTTENLRRVEE
NVQQQKATGSEVIQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LVEKETNERKCLEDENAKLQRVQYDLQKANSNATETISKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTACEDSSKRKKLEDELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVRDKQRTQEELRILSSEVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRTQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELTRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSSRETQSQLENERCRLQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYIQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVNSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFRELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSS---------GMS---SSVNDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYTY---SFSTSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFRE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSS---------GMS---SSVNDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYTY---SFSTSSIGH----

------------------------------------------------------------
---------------------------------------QN-GTCTMSRRQNTIQELLQN
CSDCLTRAELIVQPELKY--GDGVPLRGNRDLEDCFA--QANDQMDMLDGLIREMRQMGQ
PCDMYQKRLLQLQEQMRALYKAISVPRARRASSKGGGCFSSQSGSGWDEFTKRVTSECLS
WMRQQKVEMEQVKWGFDAASIEQQIC-EHRRTHNAIGDYRWHLDKVKTDLREKAAVHQLE
EEYEGLLKYSFERMDQLRQFQNLIQATSREIMWINDCEEEELLYDWSDRNTDIARKQESF
SKRMSELEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQATECYLKNLQDSIRKKFICDKSMSLQTLLEQIKELENERERILEYK
RQVQSLVNKSRKIVQLKPRNPDYRSNKPIILKALCDYKQDLKTVRKGDECILKDNNERSK
WLVTGPGGVDMLVPSVSLIIPPPNPLAVDLATKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRKEDYQKIITDLEIHYQEFLRNSQGSEMFGDEDKRKMQT
QFTDAQKHYQTLIIQLPNQPRQPQ---------TVVPTECCPVGSS---NTIIVNERNRE
HEKQEAWLLMELQKLRRQIEASEIQMVQRAPLGVDQGAMHDFSARIKDLE-GVQNDSQIM
A--ETLNKHKDLLPNFRGCEKYVYLQSEINALFQKLENINGVSAGYLDSLNALRCLLQVI
LQTEDVIRVFEVRLSEEETVPLDLDKVEAYRACLKKMKADLNMKKSLLNTLENELQRTLQ
IHSQSCQSYTLYDMDIGKYCDKVTQLID---RWQRADKQIDNRSWDLERQIKQLKTYRD-
LYQALSKWICDAKRRQDAIESMKLCDSNTIMRYLHDQKNLHSEICGKRDKVEELLKHADQ
CSAAIKDYELQVASYSSGLETLLNIPIKKSVVQSPAVLILQEANEAQSRYIELLTRSGDY
YRFLSEMLKSMEDLKMKNTKIELLEEELRLARDSNSETSNKHKFLEQNLQKYQMDISQLK
AKLMSLEEMKRQAEMDGNSAKQNLDKCYAQIKDLNDRITRLTYETEDEKRKRKLLEDRYE
QQKNDYDQLQKTRQNEKDSLGWQKLESEKVIKEKEYEIERLRVLLQD-----EGTRKREY
ENELAKVRNQFSEEMSNLKNKYAPAFNIKKVGSP--------------------------
------------------------------------------------------------
--------------------GMQLQLQEEAKTERELENELAKVRNSYDEEIISLKNKYET
EINITKNTIHQVTMQKEEETNNYRTQLDNAMRENRNLCEEIRRLKNMISQTTDNLRKIEE
NAQQQKAAGSELSQKKQQLEIELKQVIQRHSDESMRYKQSLDDASKTIKERNKEIERLRK
LLDVETSQRKEVEDENSQLKRVQFDLQKANTSATETINKLRIQEQELARLKIDYERVSQE
KKGRDQESAKFQST-KDLQIQKHKLEEELCRQNKNLMEETSRRKKLE-EIEGMRRSLRDQ
SVKITNLTQQIEEVSIVKKRNEDDLRHQREVLDGHVREKQRYMEELRKCTSDIETLRRQL
VQEQEQLKQAHLRYEHLQKTSEEKSKALNECKIEIERLQSLTENLTKEHLLLEEELRNVR
LEYDDLRMVRNEVD-EKNTTIAELKNQLQMSSKQTLELQGLLNDLQKEREKLRQEIEKFQ
KQALEASSRIQESKSQCSQIMQERETLLIKMSALEQDKARLQRLEEELNRLKVTLESESR
LKQRLESEKQQILNDLNQWKSQHSRTEESIRKIQCEREKSEREKNSLRSEIERLQMEIKR
IEERYRCRLEETAVKNQSELESERLRLQREIEKLKQRPYGAHRSTQTEEDFCIDASKLVF
SGLRKKITAMQLYECQLIDKLTLDKLLKGQRSVEEV-AADIEPYLKGAGAIAG---VSLS
PRQKYSFVEA-KRNQLLTAENAVLLLEAQAATGGVIDPHRNEILTVDSAIARDLIDFDDR
EQIYT AEKAITGFKDPFSGKTVPVSEAIKKNLVDRETG IRLLEAQLAVGGIVDPVNSVFL
PKEIALSRGLIDKDLYRMLN NCQGSTKNFIDPTTKKAVTYMQLKEKCRIEPHTGLLLLPV
QKRSMSFQGIRQPVSADALLEAGIIKESTRNDLERGAITVEEVSERIID FLQGSSCIAGI
YNEATKEKLGIYQAMKIGLVRPGTALELLEAQAATGFIVDPVSNVRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYKDPETGNIISLFQAMNKELIERGHGIRLLEAQIATGGIIDPKESYRLPVETAYKRGYFNEELNQILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDDATGLCLLPLREKKKVVHTSQKNTLRKRRVVIVDPETNREMSVQEAYSKGLIDYDTYTELAEQ---------ECEWEEITITGSDGSSRVVLVDRKTGSQYDIQDAIDKGLVERK-FFDQYRSGSLSLTQFADMISCRNGTDEVFRH-----------------------ESVARSPTVLSVRSS-SVIR--SGSFSETPDECSPIAAIFDTENLEKISISEAIQRGIVDSITGQRLLEAQACTGGIICPTTGQRLSLQEATSQGIIDQDMATRLKPAQKAFIGFEGIKGGRKRMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVRGRITIEEAIRNGLIDGRASQKLQDTNSYPKILTCPKTKLKISYKDAMNRSMVEDITGLKLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------GSRSGSRSGSRRGSFDASASSSYS-YSYSA----FSSGSILELLEAQAATGFIVDPVSNVRLPVEEAYKRGLVGI
EFKEKLLSA ERAVTGYKDPETGNIISLFQAMNKELIERGHG IRLLEAQIATGGIIDPKES
YRLPVETAYKRGYFNEELNQILSDP SDDTKGFFDPNTEENLTYLQLKERCIKDDATGLCL
LPLREKKKVVHTSQKN TLRKRRVVIVDPETNREMSVQEAYSKGLIDYDTYTELAEQ----
-----ECEWEEITITGSDGSSRVVLVDRKTGSQYDIQDAIDKGLVERK-FFDQYRSGSLS
LTQFADMISCRNGTDEVFRH-----------------------ESVARSPTVLSVRSS-S
VIR--SGSFSETPDECSPIAAIFDTENLEKISISEAIQRGIVDSITG QRLLEAQACTGGI
ICPTTGQRLSLQEATSQGIIDQDMATRLKPA QKAFIGFEGIKGGRKRMSAAEAVKEKWLP
YEAG QRFLEFQYLTGGLVDPEVRGRITIEEAIRNGLIDGRASQKLQDTNSYPKILTCPKT
KLKISYKDAMNRSMVEDITGLKLLEAASVSSKGISSPYNVSSAPGSRSGSRS--------
GSRSGSRSGSRRGSFDASASSSYS-YSYSA----FSSGSIGR----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTS------GGGGTSRIYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQS
CSDCLMRAELIVQPELKY--GDGMQLTRSRDLDECF--AQANDQMEILDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEE
DVQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSATESINKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSCEVEALRRQL
LQEQDSVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISVTEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISVTEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTC---GGVGGGGG--G-GGGG----TSR
MYY--SRRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CADCLMRAELIAQPELKY--GDGIQLSRSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKRLTGECLG
WMKQQRAEMDLMAWGVDLGAVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILKALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGSCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEGRMTLKNLLLTDQGSTHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSIRALLQAV
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
VHAQSSQQYPLYDLDLGKFNEKVMQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVIQQRSEDNAR
HKQSLEEAAKTIQEKNKEIERLKAEFQDEAKRRWEYENELGKVRNSYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTDNLRRVEE
NVQQQKATGSEMSQRKQQLEIELRQVTQMRTEEGMRYKQSLDDAAKTIQDKNKEIERLKQ
LVEKETNERKCLEDENSKLQRAQYDLQKANNSATETISKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKDLQLQKQKVEEELNRLKRSASDDSSKRKLLEEELEGMRRSLKEQ
AIKITSLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERCRLQREIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGNSG---------GLS---GGVNDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGNSG---------GLS---GGVNDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGH----

--MSINGGSHTRINTLGRLTRSESGQDISGRYEMNNYHKMVGG---------GPG---IQ
TMY--TTQV-------------------YSSETTGDSYGQ-GGTMARR--PNTVNDLLQN
ISANLGQAELVVQHELKY--GDGAQTIRNRDLDECLG--VANEQIEIVEGLIREMRAMGQ
PYEQYSRKLLQLQDQMRALYKAIHGPRMRKGSK--SGGFSSQSGSGWDEHTKRITSETLG
QIRQQRRQLEMVDWGFDASSVEQQIT-NHRKFHNAIADYRWDLDKIKADVREKGAIYQLE
EEYDCLLKASFERMDQLRQLQAIIQATSKEIMWINDHEEEELVFDWSDRNTDIPKKQESF
SKLMSELEVKEKELNKLKQESDQLILNQHPAADKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFDEAQSTENYLMNLQETIRKKYISDKSMSLQRVLDMIKDLEKEKEKINEYK
RQVQSLVNKSKKIVQLKPRNPDYKRDKPIVLKALCDYKQDQKVIHKGDECILKNNSQRSK
WNVTGPGGLDMVVPSVSLIIPPPNPLAVDLATKIEQFYEAILVLWNQLYINMKALVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYQKVVTDLEIHYQEFLRNSQGSNMFGDEDKRKMQS
QFSEAQKHYQTLVVQLPSRSTTV----------TIM---LTGYGTQIIRYNKLLSHHKKK
WEKQENMLLLELQRIRKQLESYEIRLVRNNIYNVDQETAKDFPRRISEIE-SLKGERQGV
A--TQLSRIKEMILNLKDSDKSSYLHSELSFLLKKMENINGFSADHLERLQSLRLLLQSI
LQLEDLIKVYEVRLTEEETISLDPAKVEAYRGTLKKMKMELEQKKAMLKNLDTELKSTLQ
INDRVNQTYPFYDLDMSKFLNKGNQLIE---RSQRIEKEIDDRLWELEKQSKQIKNYKD-
LSHVLGKWISDTKHKQDSLESIKLTDAITVSRCISDQKALNAEIHSKRDKVEEVVKTADI
CASGIKDYELQLASYSSGLETLLNIPIKRTMVQSPSGVITQESAEIQACYIELLTRGNDY
YRLLHELSKSLEDLKMKNTRIELLEEELRLARDANSDNSQKNKYLDQNLQKYQIECNEYK
SRILLLEDIKRKAEMDGSSAKQNLEKYYSQITELNDKITRLTYEIDDEKRRRKALEDRCE
MQKNDFDQMQKKKQNDLDAINRQRLETEKIYKEKEYEIERLKILLQD-----EGQRKREY
ENELSKVRKQYNDEISSLRTKYESEITITKTTIQQISAQKEEDTYDLKSQLEKLARDNRD
LTAEITRMNDGMAQINEHRRKAEEEAFQHKASGSELSQRKQHLETELQKLITIHSEDTAR
YKISLEEAARTIQERNSEVEKLKYQLQEEAARQRHYENELAKVRNNYDEQLINLKNKYET
EINITKTTIHEITVQKEDNIGEFRRQMDNLAKEKRDYLAEVDRLKATISQMTNNLRKTED
DVHQQKSYTSEISRKKQQLEIELRQINDLKNDLEQKSKKSLEDAAKTIQDRNKEIERLKK
IIEVETEQRKKMEDENVKLQRTQFDLQKVNSSATETINKLKIQEQDLIRLKADYEKLSLK
DQDKQSEIFRLQTNLKELQTQKLKLEEEINRQKRIATDEHTTNKKLEDELESLRRTSSEQ
LKKITHLTQQIEQITVVKKQTEDDLRQQRESLDSQLRDKQRNIDELSKLVAEVESLRRQL
HVEQENLRQAHGRNEHLQKTVEERNKSLNECKIEIERLQSITENLTKEHLRLEEELRYLR
LEHDEVKKSKDEVDGEKSATITELKNQLQTSNKRSLELQGLINELQKERQNLRQEIEKFQ
KQALEASSKIHESSSKCSEIMQEKESLLMKIKLFEQDKVRLQRLEDELNRAKAALDSETR
YKQRLEEEKNQIRNDFNQWKSQFTRKEEDVKRIETDLDRCERDKFGLKSEIERLQAEIRS
IEEGYRRKLDDVNRTM----KAQQLALESELENLRRRPPGSIKQTQTDEDMSIDPSKFLF
DGLRKKVTAHQLLECQIITKATYEKLIKGQKSVEEV-AAEVEPFLKGAGAIAG---VSVT
PKEKYSLVEA-KRKKLTSPESTVMLLQAQAATGGIIDIERNEKLTADHALARDLIEYSGK
EAIYTA EKAITGFKDPFSGKIVGVGEAINKNLISRDDG IRLLEAQVAAGGIVDPVISVYI
PVAIALSRGLIDQNLYKILNDP NDDAKYFIDPVSKKNISYAQLRKKCRVEPHTGFLLLPV
MKKSLSFPGIRHPVPMDELVQSGIIRPDTVDQLESGQITVEEVSERIKDFLQGSSCIAGI
YNEATKEKLGFYDAMNKGLLRPGTT LELLEAQAATGFIVDPVNNLRLPVEEAHRRGLVAN
EFKDKLLSA ERAVTGYKDPETGNIISLFQAMKKELIEKGHG IRLLEAQIATGGIIDPKES
HRLPVDVAYKRGYFNQEMNGILLSP DDDTKGFFDPNTEENLTYLQLKERCIVDEKTNLCL
LPLKEKKKAVQTSQ KNTLRKRRVVIVDPDTNREMTVQEAYKKGLIDYNTYIELSGQ----
-----ECEWEEITITGSDGSTRIVLVDRKSGNQYDVQEAIEMGMINKS-QLDQYRAGSIS
LTQLADMICNIN-----------------------LSDDVLVSSRHD-SSSSPRLR---T
SSWSKSGSYSDTLEETSPIAAIFDTENIEKISISEGINRGIVDTITG QRLLEAQACTGGI
INPVTGQRLSLQDAAAQGIIDHDMLSRLKQA QKAYFGFDGIRG-QTKLSAAEAMKVNWLP
YEAG QRFLEFQYITGGLVDPETQGRLTTEEAIRKGMIDGRAAQKLRDVNNYPKILTCPKT
KLKISYKEAVDRSMVEDKTSLRMLEAASVSSKGISSPYNMSSAPGSRSGSRS--------
----GSRSGSRRGSFDASSGSSSVQSSYSFSQNIFSSSSSGG----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTS------GGGGTSRIYYS---------
------RRG-------------------VITDQNSDGYCQT-GTMSRHQNQNTIQELLQS
CSDCLMRAELIVQPELKY--GDGMQLTRSRDLDECF--AQANDQMEILDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDLVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSGKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYTKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHHGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
TKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQD-----EGARKREY
ENELAKA-----------------------------------------------------
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------SNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGSIAG---ASAS
PKEKYSLVEA-KRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEDTGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSTRHD-SVSKISTISSVR
NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRLTRAESGPDLRYEVTG---GCGGGGGTSRMYYS---------
------RRG-------------------VITDQNPDGYCQT-GTMSRHQNQNTIQELLQN
CSDCLMRAELIVQPELKY--GDGIQLTRSRELDECFA--QANDQMEITDSLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLG
WMRQQRAEMDMVAWGVDLASVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDRNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKMQS
QFTDAQKHYQTLVIQLPGHPHHQ----------TVTTTEITHLGTCQDVNHNKVIETNRE
NDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELK-SVQNDSQAI
A--EVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAV
LQTEDLLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQTSQQYPLYDLDLGKFSEKVTQLTD---RWQRIDKQIDFRLWDLEKQIKQLRNYRD-
NYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFD
QQKNDYDQLQKARQCEKENLGWQKIESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFET
EINITKTTIHQLTMQKEEDTSGYRAQIDSLTKENRSLSEEVKRLKNTLAQTTENLRRVEE
DVQQHKATGSEASQRKQQLEIELRQVTQMRTEESIRYKQSLDDAAKTIQDKNKEIERLKQ
LIDKETNERKCLEDENARLQRVQYDLQKANSSVMEATNKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRFQSSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ
AIKITNLTQQVEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSCEVEALRRQL
LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADSDKNATISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKLISTESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQIASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKLSTISNVRNLTIRSSSFSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTNSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS------------SMGSGVSDDVFSSSRHE-SVSKLSTISNVR
NLTIRSSSFSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGVIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTNSYAKILTCPKT
KLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNSSYS-YS--Y---SFSSSSIGH----

--MSCNGGSHPRINTLGRMTRAESGPDLRYEMTY---SGGGGGGGGG---GGG----TSR
MYY--SRRCTVNDQNS-------------------DGYCQT-GTMSRHQNQNTIQELLQN
CADCLMRAELIAQPELKF--GEGIQLAWNRELDEYFT--QANDQMEIIDGLIREMRQMGQ
PCDAYQKRLLQLQEQMRALYKAISAPRVRRASSK--GGYTCQSGSGWDEFTKRLTGECLG
WMRQQRAEMDLMAWGVDSGSVEQHIN-SHRSIHNAIGDYRWQLDKIKADLREKSAIYQLE
EEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAF
SIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHL
KENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYK
RQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSK
WYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWH-
YCMIDIEKIRAM-TIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQS
QFTDAQKHYQTLVIQLPGHPQHQ----------TVTKTEITHVGTCQDVNHNKVIETNRE
NDKQETWLLMELQKIRRQMEHCEARMTLKNLLLTDQGSTHNITVKINELK-SVQNDSQAL
A--EVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSVRALLQAI
LQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQ
IHSQSSQQYPLYDLDLGKFTEKVTQLTD---RWQKIDKQIDFRLWDLEKQIKQLRNYRD-
NYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAEL
CANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDY
YRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFK
AKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFD
QQKNDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQE-----EGARKREY
ENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRD
LKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEVELKQVIQQRSEDNAR
HKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLRNKFET
EINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTENLRRVEE
NVQQQKASGSEMSQRKQQLEIELRQVSQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQ
LVDKETNERKCLEDENSKLQRVQYDLQKANNSATEAMSKLKVQEQELTRLRIDYERVSQE
RTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQ
AVKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLDVEALRRQL
VQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR
LEYDDLRRGRSEADNDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ
KQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETR
VKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKR
IEERCRRKLEDSTRETQSQLETERCRLQKEIDKLRQRPYGSHRETQTEYEWTVDSSKLVF
DGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEV-ASEIQPFLRGAGAIAG---ASAS
PKEKYSLVEA-KRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLI DFDDR
QQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGM RLLEAQLASGGVVDPVNSVFL
PKDVALARGLIDRDLYRS LNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSV
QKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKD FLQGSSCIAGI
YNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ---------ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLSLTQFADMISLKNGVGTSS---------GLS---GSVNDDVFSSSRHE-SVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGY---LLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKL LSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGI RLLEAQIATGGIIDPKES
HRLPVDMAYKRGYFNEELSEIL SDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCL
LPLKEKKKQVQTSQKNTLRKRRVV IVDPETNKEMSVQEAYKKGLIDYETFKE LCEQ----
-----ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRK-FFDQYRSGSLS
LTQFADMISLKNGVGTSS---------GLS---GSVNDDVFSSSRHE-SVSKISTISSVR
NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQ RLLEAQACTGGI
IHPTTGQKLSLQDAVSQGLIDQDMATR LKPAQKAFIGFEGVKG-KKKMSAAEAVKEKWLP
YEAGQ RFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKT
KLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRS----
GSRSGSRSGSRRGSFDATGNS--S-YSYSY---SFSSSSIGY----

Query Results

"ENSGT00760000119163_3"

ENSGT00760000119163_3