Query Results 

MPKSGFTKPIQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFSISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPT-QKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICENKQI
LPSKAPLS--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKDNESEAEKNSLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEVLQTKKISTSCS-VPETSNSDVQTKKD
YVVSSEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRIANLTVNTTLDCPEKTREEG
NFRKSFSPKDDTSLHLFHIATGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRFDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKVKDEDHSPTLENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDESEDLFLNMEHESLTLEKKTKF---EKS--KDDKSAKEKHIPRERNIKEERE
--KIKKESEK-FREEKIKDLKEERE-NVLTDKE--TEFSSLSVSANDESI----MEKEID
VEKQEKYIKESKEKSEKRFQTKEKDFEKTERKNFEKEKKIKHEHKSEKDKLDLSECVDRI
KDKDKVYSHHTEKFHKEGEKIRNTT-VKKTDDREKTREKIDRKHDKEKPEKERHLAESKE
KHLIEKKNKQSE-NSEYTKSDKSKSKEKDREIDKREKSRDKESINITNSKHTQEEKKPSI
VDS-NKAQHEKPLSLKEKTKDEPLKIPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKLKS----SPVSKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHALTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSSRSQSVDNKNIMNLGKSSFVS-DSSL--NRSPRSETEKLCLSSRSVSMISIASS
EDSCHTTVTTPRPPVEYDSDFMLEGSESQMSFSQSPFLSVAKSPALHERELDSLADLPDR
IKPPYANRLPASHLRSS-SVEDVKLVINEGRSIIEVRRCSMPSVIC-EHTKQFQ-TISEE
NSQGSL--LAVPRDT-CPSPKPEIF-SNVPERDHSN-VSSIHSS-FVASPTVSVNNKYVS
-TDINVIKSTAPVSTVVDSPVHLE-SNPVGV-IQNKAWEIPVDNLESVSTRDFICPNSNM
PDQ-DSSVQGFCN--SENKILKE-NTD-FLSLHQTELPANSCAQDPASF-LPSQHPCSFS
S-QSLSDA-ETISKHMSSSYVANQEPGILQQK----NAIQIINSVLDTDNESTKDTEDTF
LLADVQRTDAFVPVYSESTVQEASPNFEKTNTLPVLSSEKDFNGSDVSAQLN-THYAFSK
LTYKSSSGHEVENSTPDIQVISPEKE-KLENLVLTHL-N-RRDSDLCEMNA--GMPKGNL
NEQDNPKHCPESEKCLLSIEDEESQQSSLSSLENHSQQSAQAEMHKYAQLVKVELEENIE
YDKT-ENQIPQRMTRNKASTVANQSKQILANCTLLSEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNVKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDNAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LGMSAIEESMGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKERKVKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKLDRKHDKEKPEKERHLAESKE
KHLMEKKNKQTD-SSEYTKSEKGKNKEKDRELDKKEKCRDKESINITNYKHIQEEKKSSI
VDS-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSG-FTVSPTGASNSKYVS
-ADRNVIKNTAPVGTVMDTPVHLEQSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNACAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHVSLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSSIQEASPNFEKAYTLPVLPSEKDLNGNDASPQLN-THYAFSK
LTYKSSSGHEVENSTTDTQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMQKYGQLVKAELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRNDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-CSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTPPA-QKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
VPSKAPLP--SALDEYEFKDDDE----EEINKMIDDRHILRKELRKENESEVEKSSLFAK
QEK-TFYPKSFKSKKQKPSRVL-YSSSESSDEEILQNKKCSAPCS-VPETSNSDIQTKKE
YGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTALDCSDKTRDEG
NFRKSFSPKDDTSLHLFHISSGKSPKHSCGLSEKQSTPLKQEHSKTCLSP-GSSEMSLQP
DLVRYDN-IESEFLPESSSVKSCKHKEKNK-HHKDFHLEFGEKSNAKIKDDDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKSRDGTKELQRSVEFDREFW
KENFFKSDETEDLFLSMEHESLTLEKKSKL---EKNI-KDDKSTKEKHISKERNFKEERE
--KIKKESEKSFREEKIKDLKDDRE-NVLTDKE--TEFSSLGVSATEETIGLHSVEKEIE
IE---KHMKESKEKSEKRFQTKDKDIERADRKNSEKEKKIKHEHKSEKDRLDPSECVDRI
KEKDKLYSHHTEKCHREGEKLKNITTIKKNDDRDKSREKMDRKHDKEKPEKERHPVESKE
KHLMEKKNKPSD-NSDYTKSEKSKNKEKDREVDKKDKSRD--SVNISNSKHFQEERKSSI
TDS-NKAQHEKTLSLKEKTKDEPLRTPDGKEKDK----KDIDRYKERDKHKDKI-LSSSL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRSCLELKVKDKEK-TKHALAESKNKELTRSKSSELTDTYIKEKH
CKDAVSNRSQSVDTKNTMSLGKSSFVS-DNSL--NRSPRSESEKPGLSSRSVSLISVASS
EDSCLTTMTTPRPPVEYDSDFMLEGSDSQMSFSQSPFLPVAKSPALHDRELDSLTDLSER
IKASYASRLLTSHLRAS-SVEDAKLVTNEGRSAAEARRCSMPSVIC-EHTKQFQ-TISEE
GSQDG---SAVPREI-CPSPKSEVS-SNVPERELLS-VSNIHSS-FAASPTRSINSKYNS
-TDTNVIKGTAPLGMLMGSPVHLESSNQVGV-IQSKSWEM-----ESLNTGDFSCPNSAA
PDQ-DSSVQGFCN--PENKVLREQNID-FVSMHQTELPANTCAQDPASV-LPSQQPCSSH
S-QSLSDA-ESIPRHTSLSYVTTQEPGILQQK----NAIQMISSVLDTDTEPTKDMENTF
VLTDVQKTDAFVPVYSESTVEEAAPNFEKASTLPVLPSEKDFNGSDGSSQPN-PHYAFSK
LMFKSSSGHEAEKSTSDTQDTSHEKENKLESLVLTHL-NDKCDSDLCEMNV--GVPKGNL
SEPDNPKHCPESEKCLLSIEDEESQQSTLSSLENHPQPSAPPEMHKYGHLVKVELEESAE
DDKP-ESQIPQRMTRNKGNTGASQSKQLLASCALLPDKDS-E-SASPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPRFGSAKVVQIQNSDSDS-TMVEKPTGRKSKDKIASYNKTAKVDRNDVGKDMKEKSSMK
RKLQFNVSPSRNEDRNSDTDSDPGHTNESWGERLISTYRT-YSEKEVPEKKKMKKESG-S
KKAAPVSILFGYPLSERKQ------MALLMQMTARDNSP--DPNLNHPLQTTAT-QKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHTAAIRGDIKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNA
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRKIVKLLLRHGGNPFQANKHGERPV
DVADTEELELLLKREVPISDDEDDCSDLEETPSVNP-SSIDGNMDSETEKESLVNDTKHI
-----PIK--APLDEYEFKDEEE----DEVKKIIDDRHIPRKELRKEDESEVEQSSVFLK
QEK-VSFQKSLKNKKQ-PSRVL-YSSSESSDEDIPQDKKTISPSCTVTETSSSDTKIKKE
Y-VFNEHKQKGKVKRKVKNQSKNKENQQLKLEKDNSRGT----ILGASVLESFDKSREEE
NFRKSFSSKEESSLPLLHITASRSPKHPCGLIEKQPTPLKQENIKMCLSP-SGSEVTSQS
DLVRCDHNIDAEFLPESCSGKPYKNKDKSK-HQKEFISEFGDKSSPKHKEEDNSPSCESS
ECMMKKVDKEGKIYKKHKMKHKEREKDKHKKEQDGEKEKHKHKESSKESQRNIEFDREFW
KENFFKSDEAEDI-SNLDHESPMSERKSKL---EKVLTKDDKHVKDKKFQKEKTFREERE
KDKNKKENDK---EEKTKDIKEEKE-SIFSDKE--TELLCLG--VRDISTSMFSVEKESE
FEKQEKTTKEHREKLEKRNSA----NEKVERKNLEKEKKSKCEQKSEKDNSEFVENVEKT
KEKEKLFIHQTEKSHKENDKLKNFNAIKKLDEKEKGKEKSDKKHEKEK--NDRHLSECKE
KSCNERKAKVLEKECEYSKMEKVKNKEKEAEKKDRSKERD---SSVSNIKHASEERK-CN
T--------EKPLSFKEKPKDELLKTPDGREKDKKD--KDIDRYKERDKHKDKMQQNNVL
KLK---LEMEKFKSKT----APAPKDTRPKEKRLLNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRSCSELNKIKDKDKAKHSLAETKSKELIRSKSSELSDACVKDKL
LKDATSIRSQSVDTKNLPAVGKPLILL-DNNL--NRSPRSENEKIGLTSRSVSMISVASS
EDSCNTTVTPPRPLTEYDSDFMLEGSDSQMSFSHSPFLPSAKSPAYHE--TDSLSELPER
NKPPVSNRIPPTYVRSA-SVEDVKFVLNDCRAVVEVRRCSMPAAYE--YTKQSR--VSDE
NNHSAL--PSIQSHS-CS-PIHESQFSNLLEKDSQNTVSSLYSG-LASSPTRPINNKSNA
-SDV-VVKSAALLTPSGESHTPLEQGNQNSVTLSSKSWGVALDRLNSLNSECTCYE----
-QD-ATIAPTTHH--SDNKIIKEQKSSEPYHHQ-AENTVNVMSQDSVAF-LPLQPSCPSQ
I-HPAPDS-VGGAKHAPSPDISQ-EALLVKHQQ---SAIQATNAILDVDPISKKKMEKNV
FSN-NKKSDVLITVYPESFTKDIGPNFEK-----------DFTVNDPHIHPNGSLSVVSK
LIYKTSQTDELDNRLSDVQIQGEK--AHSDGLCLSHMACNKNDVDSQDLHA--RALKGIV
TDYNRKFFNTDNTENSLV--EENLQQ-CLSRCLENHSQLSGHEIHKYSQAIKAELEEAIE
DHKAQHYEIPQRITRNRANMLANQTKQNLAGCPQISERDS-ESSASIKGRIRLTEEDDPQ
AHHPRKRKLSRVPQPVQVNPSLMQAKEKTHQSLAAIVDALKLEEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFKQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNAPMDTQTDDGKISVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDSSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIRDLKEERE-NIPTDKD--SEFTSLGMSAIEESIGLHLVEKEVD
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNSEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-NSDYSKSEKGKNKEKDRELDKKEKSRDKESINITNYKHIQEEKKSSI
VDG-NKAQHDKPLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-IKHTPTESKNKELTRSKSSEVTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESXXXXXXXXXXXXXXXXXX--------------
------------------------------------------------XXXXXX-XXXXX
XXXXXX--XTVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSS-FAASPTGASNSKYVS
-ADRNLIKNTAPVSTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLHQTELPGNSCAQDPASL-MPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NPVQIISSALDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLSSEKDFNGSDTSTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKAQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-SMVERPYGRKSKDKIASYSKTSKIDRGDMGKEIREKSSMK
RKLPFTLSPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTRKEAG-T
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGADVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTGLCLLTVLRL-DFVS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRNDVGKEMKEK-SMK
RKLPFSISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSD----------------
------------------------------------------STPNHPSQTPPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICENKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENESEAEKNSLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEVLQNKKISTSCS-VPESSNSDIQTKKE
YVVSSEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVANLTVNTALDCPEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRFDN-TESELLPESSSVKYCKHKEKNK-HQKDFHLEFGEKSNAKLKDEDHSPTLENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDGAKELQRSVEFDREFW
KENFFKSDETEDLFLNVEHESLTLEKKSKL---EKNM-KDDKSTKEKHIPRERNCK-ERE
--KIKKESEKSYREEKIKDLKEERE-NVPTEKE--TEFSSLSISANDESVGLQSVEKEID
IEKQEKHIKESKEKSEKRFQTK--DVEKTERKNFEKEKKTKHEHKSEKDKLDLSECVDRI
KEKEKLYSHHTEKCHKEGEKIKNITTIKKTDDREKSREKMDRKHDKEKPEKDRHLAESKE
KHLMEKKNKQSD-NSEYTKSEKGKSKEKDREIDKKEKSRDKESINITNSKHTQEEKKSST
VDS-NKAQHEKPLSLKEKAKDEPLKIPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHALAESKNKELTRSKSSELTDAYTKEKQ
SKDAVSNRSQSVDTKNIMNLGKSSFVS-DNSL--NRSPRSETEKLGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSESQMSFSQSPFLPVAKSPALHERESDSLADLPER
IKPPYANRLPASHLRSS-SVEDVKLVINEGRPIVEVRRCSMPSVIC-EHTKQFQ-TISEE
SHQGSL--SAVPRDT-CPSPKPEIF-SNVPERDHSN-VSTIHSS-FAASPTRSVNNKYVS
-ADINVIKSTAAVGTVVDSPMHLESSNQVGV-IQNKSWEIPVDRLETLSTRDFICPNSQT
PDQ-ESSVQGFCN--PENKILKE-NTD-FLCLHQTDLPGNCCAQDPASF-LPSQQPCSFP
S-QSLSDA-ESISKHTSLSYVANQEPGILQQK----NATQIISSVLDTDNESTKDTEDTF
VLAEVQKTDAFVPVYSESTIQEVSPNFEKTNTLPLLPSEKNFNGTDASAQLS-THYAFSK
LTYKSSSSHEVENSTTDIQVISHEKE-KLESLVLTHL-N-RCDSDLCEMNV--GMPKGNL
NEQDNSKHCPESEKCLLSIEDEESQQSTLSSLENHSQQSAQPEMHKYSQLVKVELEENNE
DDKT-ENQIPQRMTRNKTSTMANQSKQILASCTLLSEKDT-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVSKEMREKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTSLFAK
QEK-AFYPKSFKNKKQKPSRVL-YSSTESSDEEALQNKKISTTCSVIPETSNSDTQTKKE
YVVTGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKDKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKTDKEGKTLKKHKLKHKEREKEKHKKEVEVEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDEK-TKEKHVSKERNFKEERD
--KFKKESEKSFREEK-KDLKEERE-NIPTDKD--SELISLGMSAIEESIGLHSMEKEID
IEKQEKHIKESKEKSEKRFQTKEKDIEKERK---NFEKKIKHEHKSEKDKLDLSECVDKI
REKDKLYLHHTEKCHKEGEKSK-TAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-NSEYTKSEKGKNKEKDRELDKKEKSRDKESINIANSKHVQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRNCSELKIKDKEK-TKHTPAESKNKELTRSKSSELSDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKSGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFILEGSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLPTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-DHTKQFQ-TISEE
SNQGSL--LTVPGDT-SPSPKPEVF-SNVPERELSD-VSNIHSS-LAASPTGASNSKCVS
-ADRNI-KNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWELP-DRLETLSTRDFICPHSNI
PDQ-ESSLLSFSN--PENKILKE-NAD-FFSLHQTELPGNSYAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKPMSLSYVANQEPSILHQK----NAVQIIRSVLDTDNESTKDTENTF
VLGDVQKTDAFVPLYSDGILQEASPNFEKAYTLPVLLSEKDFSGRDASTQLN-THYAFSK
LTYKSSSGHEVENSTIDIQVISHEKENKVESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQDNPKHCPESEKCLVSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DEKT-ENQIPQRMTRNKANTIANQNKPILASCTLLSEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPRSGFPKPVQSENSDSDS-NMVERPYGRKSKDKIASYSKTSKIDRGDIGKEMKEKPSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-S
KKSTPVSILFGYPLSERKQ------MALVMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAHSVNP-SSVDENIDSEPEKDPFICESK-V
LPSKAPLP--SALDEYEFKDDDE----EEIGRMIDDRHILRKEQRKESELEAEKSGLFAK
QEK-AFYCKSFKAKKQKPSRVL-YSSTDSSDEDLLQGSKRASTTCSVPETSSADTQARRE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTALDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHACGLSEKQSTPLKQEHTKACISP-GSSEMSLQP
DLARYDT-TEPEFLPENTNLKSYKHKEKSK-HQKDFHLEFGEKSNAKMKDEDHNPTFENS
ECTLKKMDKEGKTLKKHKLKHKEREKEKHRKEADSEKEKYRNKGNPEELQRGIEFDREFW
KENFFKSDETEDLFLNMEHESLT-EKKSKL---EKNM-KDDKSTKEKHVSKERSFKEERE
--KTKKESEKSLREEKL---KEDRD-SMSTEKD--VECGSVGIALNQESVGPHSAEKEMD
IEKQEKHTRE-REKSDRRFQTKEKEVEKTERKFSEKEKKMRHEHKSEKEKWDFSENVDRI
KEKDKLWSQQTERCQKEGEKTKNT--VKKTDDRERNREKVDRKHDKERPEKERCLAESKE
KHLEKK---KCD-NSEYTKSEKARN--KDREGEKKEKFRDKESINITNSRHLQEEKRSSI
GDSSSKIQHEKTVSLKEKARDEPLKTPDGKEKDK----KDIDRYKERDKRKDKIQLNTLI
KLK---SETDKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRTCLELKVKDKDK-TKHTPTESKSKEFARSRSSELTDAYNKEKQ
SKDAGSNRSQCVDSKNVLNLGKSPFIP-ENSS--NRSPRSESERLGLSSRSVSMISVASS
EDSCHT-VTTPRPPVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELESLADLPER
LKAPCTNRVPVCHLRSS-SVEDVKVIPSEARPAVEIRRCSMPSVIC-EPTKHFQ-IPE-E
SAQ-GS--LAVPRET-CPSPKPEVS-SAVPERGLPH-VSEFHPN-LAGSPTRSVNSRYIS
-SDTNVIKSVSLVGTLMDSPMNLEPSNQVGV-IQNKSWEMPAEKLESLSTNDLICPDPST
SDQ-DSSAQSFCH--SENKTLREQNTD-CLSSPQTEMPGKSCAQDAASL-LSSLQPCSFS
N-QAHSDA-ESASKAVSLSCGASQEPGVLQER----NAGHVISSVLDSDNNFTKEMENAF
VLADIQKTNSFVPVYSESTVQETLASFEKASTLLVLPSGKDFSGSDGASQMS-TQYTFSK
LTYKSSSSHQVEKSIDDTQVTSHEKEKRLQGLVLTQL-S-KCDSDLYGMDA--GMPKGSL
SDQDPAKHSPGSEKYLLPIEDEESQQSPLSSVESHSQPSAQPELHKYDQLTKGDLEESAE
DDKT-ENQHPQRLTRNKVSPVVSQSKQILAGCTLLPEKDS-D--SSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYNKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEVRSVNP-SSVDENIDSETEKDSLISESKQI
IPSKAPLP--SALDEYEFKDDDD----EELNKMIDDRHILRKELRKENESEVEKNSLFAK
QEK-AFFPKSFRSKKQKPSRVL-YSSSESSDEEILQNKKVSTPCS-VPETSNSDIQTKKE
YGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTTLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPTHSCGLSEKQSAPLKQDHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKNK-HQKDFHLEFAEKSIAKIKDEDHSPAFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDGGKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHDSLVLEKKSKL---EKNI-KDDKSPKEKHVSKERNFKEERE
--KVKKESEKSFREEK-KDLKEERE-NVPIDKE--IEFSSLGISASEDSIGLHSMEKEIE
IEKQEKHIKENKEKSEKRFQSKEKDVEKAERKNSEKEKKVKHEHKSEKDKLD-SECVDKI
KEKDKLYSHHTEKCYKEGEKIKNIT-IKKTDDREKSREKMDRKHDKEKPEKERHVVESKE
KHLMEKKNKQSD-NSDYTKSEKSKNKD--REIDKKEKSRDKES--VNNCKHFQEEKKSSI
ADS-SKVQHDKTLSVKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
RLK---SEADKPKPKS----SLVSKDIRPKEKRLLNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEKITKHALAESKNKELMRSKSSELTDAYTKEKQ
CKDAISNRSQSVDTKTIMNLGKSSFVS-DNSL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCHTTVTTPRLPVEYDSDFMLEGSDSQMSFSQSPFLPVAKSPALHERELDSLPELPER
IKPPYTSRLPTSHLRSS-SVDDVKLVINEGRPTVEVRKCSMPSVIC-EHTKQFQ-TIE-E
NNQGGL---AAPRDI-CPSPKPEVS-SNVPERELSN-VSNIHSS-FAASPSRSVNSKYIS
-TDINVIKNTAPVGTLIDSPVHLEPSNQVGV-IQNK-MEIPADRLESLSTSDFICPNSST
PDQ-DSSGQGFCN--SENKILKEQNTD-FLSLHQAELPVNSCAQDAAAF-LPSQQPCSFH
S-QSLADA-ESISKHMSLSYVANQEPGILQQK----DAVQIISSVLDTDTESTKDMENNF
PLTDVQKTDAFVPVYSESTIKEALPNFEKANTLPVLPSGKDFNGSDSSSQLN-IHYTFSK
LMYKSSIGREVENSISDIQVISHEKE-KLESLVFTNL-NDKCDSDLCE-NA--GMPKGNL
NEQDNPKLDPESEKCLLSVEDDESQQSTLSNLENHSQQPAQPEMHKDGQLIKVELEENAE
DDKT-ESQIPQRMTRNKANTMANQSKQILASCTLLPEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-TMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKETG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--ESTPNHPSQTS-A-QKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEPRSLNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKELRRESESEIEKSSLFSK
QEK-TFYAKSFKGKKQKPSRVL-YSSSESSDEEIVQNKKAPAPCS-VPETSNSDIQSKKE
YGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTLNTSLDCSEKTREET
SFRKSYSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKHEHAKTCLSP-GSSEMSLQP
DLVRFDN-TESEFLPESSNVKSCKHKEKNK-HQKDFHLEFGEKANAKVKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKETEGEKEKYKNRDGTKELQRSVEFDREFW
KENFFKSDETEDLFLNIEHESLMLEKKSKL---EKNS-KDDKSFKEKHVSKERNFKEERE
--KIKKESEKSCREEKIKDLKEERGEVIPIDKE--TEFSSIGMSVNEESVGLHAMEKEIE
IEKQEKHTKESREKFEKRYQMKEKDIEKSERKNSEKEKKIKHDHKSEN-----NECIDRI
KEKDKLCSHHTEKCHKEGERIKNVSAVKKIDDRERIREKMDRKHDKEKPEKEK-------
-HLMEKKNKQLD-NSDCTKIEKSKNKEKEKEVDRKEKSKD---ANVNNSRHFQEEKRSSM
TDS-NKAQHEKSLSLKDKTKDEPLRTPDGKEKDKKD--KDIDRYKERDKHKDRVPLNNVL
KLK---SEVDKSKLKSSKDDSKASKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRSCLELKVKDKEK-SKHALAESKNKELSRSRSSELTDVYAKEKP
SKDALSNRSQSVDNKNS-NLAKSSFVS-ENNL--NKSPRSEAEKPGLSSRSASMISVASS
EDSCHTTMTTPRPLVEYDSDFMLEGSDSQMSFSHSPFLPVAKSPALHERDMDNLAELPER
IKLPYTSRLPTSHLRSS-SVEDVKVIISEGRPTVEIRRCSMPSVIC-EHTKQFQ-TFSEE
SNQGG---LAVPRDS-CPSPKPEVS-SNVPERELSS-ISNIHSS-FAASPPSSVN-KFIL
-ADTNVIKSTASVGTLMDSPVHLEPSNQVGV-IQTKSWEIPVDSLEPLSTNDYISPNSST
LDQ-DSSVQGFCN--SENKVTKEQNTD-FLSLHQTDLPGNSCVQDSVSF-LPSQQPYSLH
S-QSLSDA-DSISKHMSVSYVVNQEPGILQQK----NAVQIISSVLDTDNEGTKDTENAF
ALTDAQKTDTFVPMYSESTTRDASPNFEKASALPILPSEKDFNGSDNSSQLN-THYVFSK
LIFKSSIDHEVENSTSDIQVISHEKENKMETLVLTHL-NDKCDSDLCDMNV--GIPKGNL
HELDPPKHCSESEKCLLSIEDEESQQSTLSSLENHSQQSAQPEMHKYSQLVKVELEENGD
DDKN-ESQIPQRMTRNKANTIANQSKQILPSCTILSEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-SMVERPYGRKSKDKIASYSKTSKIDRGDMGKEMREKPSMK
RKLPFTVSPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-T
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAQSVNP-SSVDENIDSETEKDSFVCGSK-I
LPSKAPLP--SALDEYEFKDDDE----EEISKMIDDRHILRKEQRRENESEAERSGLFAK
QEK-TFYSKSFKTKKQKPSRVL-CSSTESSDEEGLQNRKISTACS-VAESSHPDMQAKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRIATLTVNTALDCSEKYREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQ-TPLKQEHTKACISP-GSSEMSLQP
DLTRYDN-AEP----ESSNVKSYKHKEKNK-QQKDFHIEFGEKSNAKIKDEDHNPAFENS
DCTLKKMDKEGKTLKKHKLKHKEKDKEKHKKEVEGEKEKYKNKDNAKELQRSIEFDREFW
KENFFKSDETEDLFLTMEHESII-EKKTKM---EKNM-KDDRSAKEKHVSKERNFKEERE
--KTKKENEKSLREEKVKDPKEEKD-SVSTEKE--AECCSVGVSVSQEAAGLHSSEKEMD
AEKQERHTKE-REKSDRRFQTKEKELDRNERKFSEKEKKIKHEHKSEREKLDFSDCTDRV
REKDKLYSHQTERCHKDSEKLKNT--VRKTDDRERNREKADRKHDREKPERERYLAENKE
KHLEKRK--QSD-SSEYSKSEKVRTKDRDREGEKKEKLRDKESVNVTNLKHLQEERKSST
GDSSGKTQHEKALSLKERARDEPLKTPDGKEKDK----KDIDRYKERDKRKDKAQLNTLI
RLK---SETEKLKPKL----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRTCLELKVKDKEK-TKHAPTESKSKELTRSRSSELTDVYSKEKQ
SKDVGSNRSQSVDNRNVLNLGKPSYIS-ESGS--NRSPRSEGERLGLSSRSVSMLSVASS
EDSCHT-VTTPRPLVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELEGLTELPDR
LKPPYTNRLPVCHLRSS-SVEDVKLITNEVRPAVEIRRCSMPSVIC-EPIKHFQ-VSE-E
SSQ-GN--LAVPRET-CLSPKPEVS-SAVPERGLSH-VSDLHPN-CTGSPTRSANSSYIS
-SDVNVIKSATLVGTLIDSSMHLEPSNQVGV-IPSKSWETPVDKLESLSTNDFICPDSNI
SDQ-DSSAQSFYN--SENKMLREQNTD-CLPPHQPELPGNSCAQDPASF-LSSPQPCSFS
N-QPLAGA-DSVPKPVSLSYVVSQEPGVLQQK----SAAQMASSVLDSDNNFPEDVENTF
VLADIQKTNSFLPAYSESTVQEALPSFEKANTLLVLPSEKDFNGSDTA-QPN-THYAFSK
LTYKSSNSQEIEKGPDDTQIISHEKENKLQSLVLTQL-S-KCDSDLYEMNA--GLPKGNL
NEQDNPKHGLDSEKYSLSTEDEESQQSTLSSVENHSQQSAQPEMHKYDQLSKVELEENAE
DDKT-ENQTPQRVTRNKASTVVNPSKPMLAGCALVAEKDN-E--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIEPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSLSIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFTSLGMSAIEESIGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-NSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHILEEKKSSI
VDG-NKAQHEKPLSLKEK-KDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQINSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSEVTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSASHLRSS-SVEDVKLIISEGRPTIEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LIVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSS-FATSPTGASNSKYVS
-ADRNLIKNTAPVSTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDYICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLRQTELPGNSCAQDPASF-MPPQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQIISSALDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDTQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSTQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKTLSSKATPSENSDSDCNTMVEKPTGRKNKEKISAFSRTPKLDRSEISNEMKEKSSMK
RKLPFTLSPTRTEERDSDTDSEPEHTSENWGERLT-PFST-YPEKEGPEKKKIKRESG-S
KKSTPVNILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQATPT-QKKTP
SSSTRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDISQVKELIRMGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNM
GFYDVAKVLIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDAASSGHRDIVKLLLRHGGNAFQANKHGARPV
DVAETEELEQLLKREVPISDDDESYSDSEEPQFNNL-SSVDENLDSEGEKESLINESKHG
AIKGTSCT--SGLDEYEFKDDEDDEDDPEISKMFDDKHLLRNDIKKENTEARMNDSFFIK
QDK-VDFPKMYKNRKPKPSRLL-FSSSDSSDDDLLPDKV-----SLISESLNSDIRSKKD
YSVLHEQKEKGKVRRKLKNQSKNKENQQLKQERDKKENMKVVNMVVCPSLDSLDKSREED
MFRKSLCTKEEPSLQLFQITPGKSPKHTYTLIDKQSTPLKQENTKMCVSPPGGSESSLQT
DLFRYDQNTDAEYAIESSSSSFSKYKEKSK-HIKEFFIDYADKSILKCKEEGKSPSFEAS
ECVPKKSDKEGKVVKKHKIKHKEKEKEKSRKDPDVENDRTKHRENNKNIQRQIEFDREFW
KENFFKTDENDEEFLIMDSKNNSSEKKVKL---EKSQTKEDCSVRENHIPIENVKDEQEE
--PSKLDQEKIQKEEKGKDCNSETD-CLHTPKEKDTKMFPLTVFVKEDS---FPIDREID
TEK---PFKEGKEKSEKRSALKERDLE---KKSIDKEKKAKSEHKSEREKVEMPEITDKS
KS----HLQSPDKLQKESDKIRASVISKKNDDKEKSKDKKE------RNEKDKHLGE--H
KLCTDRKPKHTEKDSDSSRADKAKRREK----ELRKKSREGDYSAGASSKHGQEDRKQSG
NTDSSKVLHEKPAVVKEKLKEEQQKVPEHKEKDRKDKEKDIDRYKERDKHKDKTQTNIP-
KLKPKDSEAEKCKS-K----LQSTKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKHRNSVELS--KTKEKPKHSPTPSKNKELTRSKSSELSDLYTKEKP
LKEATSCRSNSVDAKNLTASGKTLLILENSNI--TRSPRSESEKTGLCSRSVSMISVASS
EESCHATVTTPRPTTEYDSDFALEGSDSQMSFSQSPFLPTAKSPATHDRDLDSIAELPDR
VKPPVTNRLLPGYLRSA-SVEDVKLVISECRPVVEVRRCSMPAALV-DQTKPTQ-TVLES
SIPEVPSSVKITPNR-CVSPKPEVSPAS--EKDTQNSTYLLASS-KK-----SLSFSRHA
-LDANLTSPSTQTS--------DGSCLYSGTESPVTHIATPA-AFECEHTKLSCSGNDSP
VLSENQTCQEMLSSRQENTRPVIQECPVLPPQPQSNLVVNTAVSDPLYF-SKTNPPISSK
QVHAIVNE-EQT--HC-----ANSSSVKIEDSESEVKLIQTEDTSL-------CSAESSV
NSQTIE---SIKIVLTDVTVED-------------LPSEGD-----EAMQVST--EVNTD
ISLCNPEGIELENIA-DSDSAPKQDKSITENTASSALINVKCDTDIVQGCETTEITKDNP
DQQVIPQ--SSSAHTTESPKTEQPQY-PLSAFESPLPQL-DQDMQSFSQPAKMEAEE-NT
EEKAEHQEIPQRITRNRANMLANQNKQVQTNYSHSSDKETVESPVSLRGRIRLTEEDDVQ
VHHPRKRKMARVPQPGLANSSVMQAKEKTQQSLAAVVDSLKLDDIQPYQSERANPYFEYL
HIRRKVEERRKMLCSVIPQAPQYYDEYVTFNGSYLLDGNPFSKLCIPTITPPPSLSEPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQSLPFSACTVLLDAE
VYNVPQESQTEDGKASVRDRFNARQFMSWLQDVDEKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSVSIYEIQEFSVPLVEVNDDFELTPI

------------------------------SKEKISSYSKTPKVDRNDVGKEVKEKSSMK
RKLPFTISPSRNEDRDSDTDSEPGHTSENWGERIISSYRT-YSEKEGPEKKKTKKESG-N
KKSTPVSILFGYPLSERKQ------MALVMQMTARDNSPXXXXXXXXXXXXXXXXXXXXX
XXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

XXWTPLHEACNV
GYYDVAKVLIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNAFQANKHGERPV
DVAETEELELLLKREVPLSDDDESFTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX-XXXXXXXXXXXXXXXXXXXXXX
--XX-XXXXXXXXXXXXXXXXXXXX-XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXEKDLERSERKNTEKEKKIKHDHKPERDRLDLNECIEKA
KEKDRGNSQQTEKYHKESEKIKNVATVKKADDREKSRDKMDKKHDKEKTEKERHLGESKE
KHFIEKKGKLSDKDSEYIKFEKSRTKEKEREVEKREKSRDKESFSLAVSKHVQEERRSTS
-TESSKTLHEKLSSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHRDKIQINNLP
KHK---SEVDKPKPKS----SLTPKDIRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRSCLELNKVKDKEKTKNTLAESKNKELIRSKSSELSDIYTKEKH
LKDATNNRSQSVDTKHITNVGKSSLII-DNNL--SRSPRSESEKTGLSSRSVSMISVASS
EDSCHTTVTTPRPVVEYDSDFVLEGSDSQMSFSQSPFLPVAKSPALHERELDSLTELPER
IKLPHANRLPTSHLRSS-SVEDVKLIINECRPVVEVRRCSIPPVIS-EHTKQLQ-TTSEE
NNQSRL--LAVPSHI-CSSPKHEVSSCNVPENDLSK-VS----NSFATSPVTSFNSKHSS
-SDTNVIKSTVQMSPVRENPMHVEPCNLINMTQQNKSWEIPVERLESLNTSDFNCSSYGV
PDQ-EPVIQGLCN--PDNRILKEQNTSELLPQHQTEIQGNSGAQDSASF-MPPQPPCSFH
A-QALPDA-ECIPKHTSLSYVGSESAF--QQK-----ILVQNNCILDTDNNF-KDLENTF
FPTD-GKTDSFVTVYAEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIERXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXADDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-SMVERPYGRKSKDKIASYSKTSKIDRGDMGKEIREKSSMK
RKLPFTLSPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTRKEAG-T
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGADVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAQSVNP-SSVDENIDSETEKDSFVCGSQ-S
LPSKAPLP--SALDEYEFKDDDG----EEISKMIDGRHILRREQRKENESEAERSGLFAK
QEK-PFYSKSFKTKKQKPSRVL-YSSTESSDEEVLQNRKISTACS-VAETSHSDVQAKRE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRIANLAVNTALDCSERNREDG
AFRRSFSPKDDASLHLLHMPTGKSPKHPCGLSEKQATPLKQDHMKTCISP-GSSETSLQP
ELSRYEN-AEPEFLPESSNVKPYKHKEKNK-HQKDFHLEFGEKSNAKIKDEDHSAAFENS
DCTLKKMDKEGKTLKKHKLKHKERDKEKHRKEAEGEKEKYKSRDNAKEPQRSIEFDREFW
KENFFKSDETEDLFLNMEHESLT-EKKSKV---EKTV-KDDRLAKDKHASKERNCKEERE
--KTKRENEKSLKEERLKDPKEEKD-GVSAEKE--AEGSSMAVSANQETSGPHSSEREVD
IEKQERHSKE-REKSDRRFQTKEKELDRTERKVSEKEKKLKHEHKSEREKLDFSDCTDRV
KEKDRLYSPQTERCHKEGEKMRNT--VRKAEDRERAREKTDRKHDREKPERERCLAESKE
KYLEKRK--QSD-NSEYSKSEKVRNRDRDREGEKKEKLRDKESVNVANLRHLQEERKSST
GEGSSKTQHEKALSLKERVRDEPLKIPDGKEKDK----KDIDRYKERDKRKEKAQLSTLI
RLK---SETEKLKPKL----SPASKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRSCLELKVKDKEK-TKHTPSESKNKELTRSRSSELTDVYNKEKQ
SKDVGSNRSQSVDNKSVLSLGKLPYVS-ENSS--SRSPRSEGEKLGLSSRSVSMLSVASS
EDSCHT-VTTPRPLVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELESLAELPER
LKPPYANRLPVCHLRSS-SVEDVKLITNEVRPAVEIRRCSMPSVIC-EPIKHFQ-VSE-D
SSQ-GN--LAVPRET-SLSPRPEVS--LVPERGLSH-VSDLHPR-CTDSPVRSVDSSSVS
-SDVHVIKSAALVGTLIDTSMHLETSNQVGV-IQSKSWETPVDKLESLSTNDFICPDSST
SDQ-DSSAQSFYH--SENKMLREQNAD-CLPVHQTELPGNSCAQDPASFTLSSPQPCSFT
N-QSLSDA-ESLPKPVSLSYGASQEPGVLQQR----SAAHMISSVLESDNNFTKEVESSF
VLADIQKTNSFVPAYSESTVQETLPNFEKANTLLVLPSEKDFSGSDAASQLN-THYAFSK
LTYKSSSSHEIEKGPDDTQVISHEKENKLQSLVLTPL-S-KCDSDLYEVNA--GMPKGNL
NEQDNPKHGPDSEKDSLSTEDEESQQSTLSSVENHSQQSAQPEIQKYDQMVKGELEENAE
DDKT-ENQTPQRMTRNKASALVSQSKQVLAGCTLLPEKDN-D--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAALVDSLKLDEIEPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKSVQSENSDSDS-SMVERPYGRKSKDKIASYSKTSKIDRGDMGKEMREKPSMK
RKLPFTVSPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-T
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAQSVNP-SSVDENIDSETEKDSFVCGSK-I
LPSKAPLP--SALDEYEFKDDDE----EEISKMIDDRHILRKEQRRENESEAERSGLFAK
QEK-TFYSKSFKTKKQKPSRVL-CSSTESSDEEVLQNRKISTACS-VAESSHPDMQAKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRIATLTVNTALDCSEKYREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQ-TPLKQEHTKACISP-GSSEMSLQP
DLTRYDN-AEP----ESSNVKSYKHKEKNK-HQKDFHIEFGEKSNAKIKDEDHNPAFENS
DCTLKKMDKEGKTLKKHKLKHKEKDKEKHKKEVEGEKEKYKNKDNAKELQRSIEFDREFW
KENFFKSDETEDLFLTMEHESII-EKKTKM---EKNM-KDDRSAKEKHVSKERNFKEERE
--KTKKENEKSLREEKVKDPKEEKD-SVSTEKE--AECCSVGVSVSQEAAGLHSSEKEMD
AEKQERHTKE-REKSDRRFQTKEKELDRNERKFSEKEKKIKHEHKSEREKLDFSDCADRV
REKDKLYSHQTERCHKDSEKLKNT--VRKTDDRERNREKADRKHDREKPERERYLAESKE
KHLEKRK--QSD-SSEYSKSEKVRTKDRDREGEKKEKLRDKESVNVTNLKHLQEERKSST
GDSSGKTQHEKALSLKERARDEPLKTPDGKEKDK----KDIDRYKERDKRKEKAQLNTLI
RLK---SETEKLKPKL----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRTCLELKVKDKEK-TKHAPTESKSKELTRSRSSELTDVYSKEKQ
SKDVGSNRSQSVDNRNVLNLGKPSYIS-ESGS--NRSPRSEGERLGLSSRSVSMLSVASS
EDSCHT-VTTPRPLVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELEGLTELPDR
LKPPYTNRLPVCHLRSS-SVEDVKLITNEVRPAVEIRRCSMPSVIC-EPIKHFQ-VSE-E
SSQ-GN--LAVPRET-CPSPKPEVS-SAVPERGLSR-VSDLHPN-CTGSPTRSANSSYIS
-CDVNVIKSATLVGTLIDSSMHLEPSNQVGV-IPSKSWETPVDKLESLSTNDFICPDSNI
SDQ-DSSAQSFYN--SENKMLREQNTD-CLPLHQPELPGNSCAQDPASF-LSSPQPCSFS
N-QPLAGA-DSVPKPVSLSCVVSQEPGVLQQK----SAAQMASSVLDSDNNFPEDVENTF
VLADIQKTNSFLPAYSESTVQEALPSFEKANTLLVLPSEKDFNGSDTA-QPN-THYAFSK
LTYKSSNSQEIEKGPDDTQIISHEKENKLQSLVLTQL-S-KCDSDLYEMTA--ELPKGNL
NEQDNPKHGLDSEKYSLSTEDEESQQSTLSSVENHSQQSAQPEMPKYDQLSKVELEENAE
DDKT-ENQTPQRVTRNKASTVVNPSKPTLAGCALVAEKDN-E--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIEPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSLSIYEIQEFYVPLVDVNDDFELTPI

MPKSGFAKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTTKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTAA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLLCESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENESEAEKSSLFAK
QEK-SFYSKSFKSKKQKSSRVL-YSSTESSDEEVLQNKKVSTACS-IPETSNSDIQTKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVTTALDCPEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYEN-TESEFLPESSCVKSYKHKEKNK-HQKDFHLEFGEKSNTKLKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKDREKEKHKKEIEGEKEKYKNKDGTKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---DKNI-KDDKPTKEKYTSKERNFKEERE
--KIKKESEKTFREDKIKDLKEERE-NVPTDKE--TEFSSSCLILNEESVGLHSIEKEMD
IEKQEKHTKESKEKSEKRFPTKEKDVEKTERKNSEKEKKIKHEHKSERDKLDFSDCVERI
KEKDKLYSHHTEKCYKESEKIKNST-TKKTDDREKNREKMDRKHDKEKTEKERHLAESKE
KHL-EKRNKQSD-NSEYAKSEKGRSKDKDREVDKKEKSRDKESINIANSKHLMEEKKSST
LDSSSKAQHEKTLSLKEKTKDEPLKTPDGKEKDKKD--RDIDRYKERDKHKDKIHLNSLL
KLK---SETDKSKSKS----SPASKDIRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLEVKVKDKEK-AKHALVESKNKELSRSKSSELVDAYTKEKQ
SKDAVSNRSQSVDTKNVITLGKSSFVS-DSSL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPLVEYDSDFMLEGSESQMSFSQSPFLPIAKSPALHDRELDSLAELPDR
IKPSYANRLPASHLRSS-SVEDVKLVINEGRPIVEVRRCSMPSVIC-EHTKQFQ-TVSEE
SNQGSL--SAVPRDI-CPSPKPELS-SNVPEKDLSN-VSNIHSS-FVTSPTRSVNSRYIS
-TDINVIKNTAPVGA-MDSPVHVEPSNQVGV-IQNKSWEIPVDRLESLSTGDFICTNTSI
PDQ-DSSVPGFCN--SENKVLKEHHTD-FLSLHQTELPGNSCAQDAASF-LPSQQPCSFS
S-QSLSDA-ESISKHVSLSYVANQEPSILQQK----NTVQMITSVLDTDNESTKDMENSF
ILADV-------SVYSESTSQEASPNFDKANTLSILPSEKDFNISDTSSQLN-THYAFSK
LAYKSSSGHEVENSSPDIQVISHEKENKLESLVLSHL-N-KCDSDLCEMNV--GMPKGNL
NEQDNPKHCPESEKCLLSIEDEESQQSTLSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANMVANQSKQLLSSCALLPEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDMGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQTTPA-QKKTP
TSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTGLFSRRGGAR-L----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

MPKSGFTKPVQSENSDSNS-NTVEKPYGRKNKDKIASYSKTPKIDLSDVSNEMKEKSSMK
RKLPFTISPSRNKERDSDTE----------------------------------KEEAGN
KKSTPVSILFGYPLSEQKQ------MAPLMQMMAIDNSP--DSTPSHPSQTTPAS-QKTL
SSSSCQKGKVS

PF12796 // ENSGT00760000119090_6_Domain_0 (192, 259)

KRNERGETPSHMATIRGDVKQVKEFVSLEANVNVKDFAGWTPRYEACNV
GYYDVAKILTAARADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 264)

QGLED

PF00023 // ENSGT00760000119090_6_Domain_2 (264, 291)

DTPLHDSASSGHRDIVKLLLLHVGNPFQANKHGEHPV
DVAETEELELLLKGEMPLSDDDESYTGLFQITYIQLFDIFDRTFWIHL------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETQELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTSLFAK
QEK-AFYPKSFKNKKQKPSRVL-YSSTESSDEEALQNKKISTTVSVIPETSNSDTQTKKE
YVVTGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHCCGLSEKQSTPLKQEYTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKDKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTPKKTDKEGKTLKKHKLKHKEREKEKHKKEVEVEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDEK-TKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFISLGMSAIEESIGLHSVEKEID
IEKQEKHIKESKEKSEKRFQTKEKDIEKERK---NFEKKIKHEHKSEKDKLDLSECVDKV
REKDKLYLHHTEKCHKEGEKSKNTAAVKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHL-EKKNKQSD-NSEYTKSEKGKSKEKDRELDKKEKSRDKESINIANSKHVQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRNSLELKIKDKEK-TKHTPTESKIKELTRSKSSELSDAYTKEKQ
LKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKSGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLPTSHLRSS-SVEDVKLIVSEGRPTVEVRRCSMPSAIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSD-VSNIHSS-LAASPTGASSSKCVS
-TDRNIIKNTAAVGTVMDSPVHLEPSSQVGV-IQNKSWEMP-DRLETLSTRDFICPHSNI
PDQ-DSSLVSFSN--SENKILKE-NAD-FLSLHQTELPGNSCAQDPASF-MPSQQLCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQIISSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIREASPNFEKAYTLPVLPSEKDFNGSDASTQLN-THYPFSK
LTYKSSSGHEVENSTVDIQVISHEKENKVESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQDNPKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENSE
DDKT-ENQIPQRMTRNKANTIANQNKPILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGSTKTAQIENSDSDS-TMVEKPAARKSKDKIASYSKSPKVDRSDVGKEMKEKSSMK
RKLPFTISPSRNEDRNSDT------------------------EKEGPEKKKVKKDAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSNLNHPLQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRNIVKLLLRHGGNPFQANKHGERPV
DVAETEELEMLLKREVPISDDEDSCSDSEEAPSVNP-SSVEGNVDSEVEKDSVANGSKQI
VHSKAPHP--PALDEYEFKDDDE----DEMKKMIDDRHILRKDVRKEDETEVEKNSLFAK
QDK-VSYSKSLKNKKQKPSRVL-YSSSESSDEEIVQDKKIVS-PCSVSETSSSDVRAKKE
CVVTNEHKQKGKVKKKVKNQSKNKENQELKQEKENA---RVTNIA-ASGLDSLDKTRDEE
TFKKSFSQKDDSSLQLFHIAAGKSPKHPCGLSEKQATALKQENTKTCLSP-GGSEITLQP
ELVRCDHSVDSEYLVESSSGKSCKHKEKSKHHQKDFQLEFGEKSSPKIKDEDNSSTFENS
EYTLRKIDKEGKALKKHKLKHKEREKDKDKKEQDGEKEKHK--HNIKESQRSIEFDREFW
KENFFKSDDSEDTLLNTEHETLPSDRKSKL---EKAVAKEDRLAKERQFHKERNAREER-
-EKNKKENEKFLKDEKMKDSKEEKE-TILADKE--MEMFCLS--VKDEVISMHLIEKEAD
TEKHEKNLKENKE---KRTSAKEKDVEKAERKNGEKEKKIKHECKT--EKAEVNENMEKV
KEKTN--FQQAERCHKENDKIKSTGALKKLDEKEKNKEKMEKKHDKEKVDKDRHLADSKE
KHCIERKVKQSEKESEYTKSEKNRTKDKEKEPERRDKSKDKETSTVVNSKHVQEERR-CN
IADSNKSMHDKLTSLKEKQKDDFLKTPDGREKDKKD--KDIDRYKERDKHK--QHQSSLL
KLK---LEHEKLKPKT----SPAPKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRTCLELS--KIKEKQRQSLPEVKNKELTRSKSSELPDFCMKEKQ
QKEATSSRSQSVDTRNVNVIKS--LLV-LDNA--NKSPKSEGEKMGLSSKSVSIISVASS
EDSCHTTVTTPRPAMECDSDFVLEGADSQMSFSQSPFLPTAKSPALLERETDGVAELSDR
MKPSFANRLPPAYIRSA-SFEDFKLVLNECRPVVEVRRCSMPASVS-EHSKPPR--ISEE
NNQNAQ--MSVQTYP-STSPKPEL-PCSMVERDIQSSFS----G-LRSSPTGAVSNKQVT
-MGTSTIKNTAQISPSEECNIHLEPCSQSGVTQQTKPWDVPFDRLNSINNECSSSGYDVS
EQD-TNNFVAMHN--SETRTIKEQKVAEYLPQP-AEIKGNSSSQESASF-LPSQSPCSLP
I-QPLP----EGSKHISSPGISNQDSLP-VQQ----NLVQTVSSAFNTDASSTRETENVF
IPSNIKKADAPHAIYSEGSAKDISEICERVNDLPVVVLERDIPESDGTSQLNVNSYVFNK
LVCKNTQIE-VDGNTVDTSNFRNEKDQQ-ENLISVHVVNSKADTDLCDLRS--AMSQGIM
NNSSNKKPCTADGEDVLT--DEAPQYS-LSNSENNSQEIIQEEVHKYSQIVKLE-EI-AE
DQKMEQQEVPQRITRNRANVLANQGKQNPVVCMQTLEKES-ELLASMKGRIRLTEDDDGQ
VHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAVVDSLKLEEIQPYCSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFKQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDAQADDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTSLYAK
QEK-AFYPKSFKNKKQKPSRVL-YSSTESSDEEALQNKKISTTCSLIPETSNSDTQTKKE
YVVTGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKDKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKTDKEGKTLKKHKLKHKEREKEKHKKEVEVEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDEK-TKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKELKEERE-NIPTDKD--SEFISLSMSAIEESIGLHSVEKEID
IEKQEKHIKESKEKSEKRFQTKEKDIEKERK---NFEKKIKHEHKSEKDKLDLSECVDKI
REKDKLYLHHTEKCHKEGEKTKNTTAVKKTDDREKSREKMDRKHDKEKPEKERHVAESKE
KHL-EKKNKQSD-NNEYTKSEKGKSKEKDRELDKKEKSRDKESINIANSKHVQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KPK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRNCLELKIKDKEK-TKHTPAESKNKELTRSKSSELSDAYAKEKQ
PKDAMSSRSQSVDTKNVMTLGKSSFVS-DNIL--NKSPRSENEKSGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSESQTSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLPTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-VISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSD-VSNIRSS-LAASPTGASNSKCVS
-ADRNIIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMP-DRLETIGTRDFICPHSNV
TDQ-ESSLVSFSN--SENKILKE-NAD-FLSLRQTELPGNSCAQDPASF-IPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQIISSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTVQEASPNFEKAYTLPVLPSEKDFNGSDASTQLN-THYAFSK
LTYKSSSGHEVENSTVDIQVISHEKENKVESLVLTHF-N-RCDSDLCEMNA--GMPKGNL
NEQDNPKHGPESEKCLPSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQNKPILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-SMVERPYGRKSKDKIASYSKTSKIDRGDMGKEMREKPSMK
RKLPFTVSPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-T
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAQSVNP-SSVDENIDSETEKDSFVCGSK-I
LPSKAPLP--SALDEYEFKDDDE----EEISKMIDDRHILRKEQRRENESEADRSGLFAK
QEK-TFYSKSFKTKKQKPSRVL-CSSTESSDEEVLQSRKISTACS-VAETSHSDMQAKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRIATLTVNTALDCSEKYREEG
NFRKSFSPKDETSLHLFHISTGKSPKHSCGLSEKQ-TPLKQDHTKACISP-GSSEVSLQP
DLPRYDN-AEP----ESSNIKSYKHKDKNK-HQKEFHIEFGEKSNAKIKDEDHNPAFENS
DCTLKKMDKEGKTLKKHKLKHKEKDKEKHKKEVEGEKEKYKNKDNAKELQRSIEFDREFW
KENFFKSDETEDLFLTMEHESLI-DKKSKM---EKNM-KDDRSAKEKHVSKERNFKEERE
--KTKKENEKSLREEKVKDPKEEKD-SASTEKE--AECCSVGVSASQEAAGLHLSEKEMD
AEKQERHTKE-REKSDRRFQTKEKELDRNERKFSEKEKKIKHEHKSEKEKLDFSDCTDRV
REKDKLYSHQTERCHKESEKLKNP--VRKTDDRERNREKADRKHDREKPERERYLAESKE
KHLEKRK--QSD-SSECSKSEKVRTRDRDREGEKKEKPREKESVNATNVKHLQEERKAST
GDSSAKTQHEKALSLKERARDEPLKTPDGKEKDK----KDIDRYKERDKRKEKAQLNTLI
RLK---SETEKLKPKL----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRTCLELKVKDKEK-AKHAPTESKSKELTRSRSSELTDAYNKEKQ
CKDVGSHRSQSVDNKNALNLGKPSYIS-ESGS--NRSPRSEGERLGLSSRSVSMLSVASS
EDSCHT-VTTPRPLVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELEGLTEVPER
LKPPYTNRLPVCHLRSS-SVEDVKLITNEVRPAVEIRRCSMPSVIC-EPIKHFQ-VSE-E
SSQ-GN--LAVPRET-CLSPKPEVS-SAVPERGLSH-VSDLHPN-CTGSPTRSANSSYIS
-SDVNVIKSATLVGTLIDSSMHLEPSNQVGV-IPSKSWETPVDKLESLSTNDFICPDSNT
SDQ-DSSAQRFYN--SENKMLREQNTD-CLPLQQPELPGNSCAQDPASF-LSSPQPCSFS
N-QPLAGA-DSVPKPVSLSYVVSQEPGVLQQR----SAAQMASSVLDSDNNFPEDVENTF
VLADIQKTNSFLPAYSESTVQEALPSFEKANSLLVLPSEKDFNGSDTA-QPN-THYAFSK
LTYKSSNSQEIEKGPDDNQIISHEKENKLQSLVLTQL-S-KCDSDLYEMNA--GLPKGNL
NEQDNPKHGPDSEKYSLSTEDEESQQSTLSSVENHSQQSAQPEMHKYDQLSKVELEENAE
DDKT-ENQTPQRMTRNKASTVVNPSKPMLAGCTLVAEKDN-E--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIEPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSLSIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPCGRKSKDKITSYSKTPKIDQSDVVKEMKEKSSMK
RKLPFPVSPSRNEERDSDTSR-------------------TYSEKEGPEKKKTKKEAA-S
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DTTPNHLSQTTPA-PKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKRVTELISLGXXXXXXX

ENSGT00760000119090_6_Linker_0_1 (228, 229)

X

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

XXWTPLHEACNV
GYYDVAKLLIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPFSDDDGSYTDSEEAQSINP-SSVDENIDSETEKDSLICESKQI
IPSKAPLS--SALDEYEFKDDDD----EEINKMIDDRHILRKELRKENESEVEKNSTFAK
QEKTAFYPKSFKGKKQKPSRVL-YSSSESSDEEILQSKKLSAPCS-VPETSNSDLQTRKE
YVVSNEQKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRATNLTVNTALDCSDKIREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSFQS
DLVRYDN-TESEFLPENSSVKS-KHKDKSK-HQKDFHLEPGEKSNTKIKDEDHSPAYENS
DCTLKKMDREGKTLKKHKLKHKEREKEKHKKDIDGEKEKYKNKDGAKELQRSVEFDREFW
KENFFKSDETEDLFLNTEHESLTLEKKSKL---DKNI-REDRSTKEKHISKERNFKEEQE
--KIKKENEKSLKEEKIKDLKEERN-NVPTDKE--TELSSLGVSTKEESTGLHSVEKEVX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
-XXXXX--XXXX-XXXXXXXXXXX---XXXXXX-----XX--XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX
XXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XXXXXXXXX--XXXXXXXXQNT-DFVSLHQSELPGKSSAQDPSSF-VTSQQPCSLH
S-QSFSDA-ESISKHMSLLHVAKQEPGILQQK----NSVQMISSVLDIDHESKKDMENTF
VPEHVQKTDVFVSEDSESTIQEASPHFEKANALSELPSEKNVNGNDASSQLN-AHYAFSR
LMYKSSSGHGIEDKTTDIQVISHEKENKLEGLVLTYL-N-KYDSDLCEANA--GIPKGNL
NEQDNPKHCPESEKCLLSIEDDESQQSTLSNLDNHSQHSTQPEMHKYGQLVKVEIEENAE
DDKT-ENQIPQRITRNRASTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
VHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIP-APQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLK-------------------
------------------------------------------

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTSKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNVKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LSMSAIEESMGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKERKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKSKNTVAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-SSEYTKSEKGKNKEKDRELDKKEKSRDKESINTTNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDREK-TKHTPTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFVSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-MSNIHSG-FTISPTGASNSKYVS
-ADRNVIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNSCAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGNDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMQKYGQLVKAELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGSTKPIQSENSDSDG-NMVEKPSGRKSKEKISSYSKTPKVDRNDVGKEMKEKSSMK
RKLPFTISPSRNEDRDSDTDSDLGHTSKNWGKRLISSYRTLFPEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALVMQMTARDNSPVTDSTPNHPSQTTPAAQKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 289)

DDDTPLHDSASSGHRDIVKLLLRHGGNAFQANKHGERPV
DVAETEELELLLKREVPLSDDDESFTDSEETPSVNP-SSVDENIDSEAEKDSLVSESKQL
ISNKAPLP--SALDEYEFKDDDD----DEINKMIDDRHILRKELRKENESEIEK-NLFGK
QEK--VYPKLFKSKKQKPSRVL-YSSSESSDEEMLQDKKVVSAPCSVPETSTSDLRSKKE
YLVANEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRITNLVCNPVLDSLDKTKEEE
NFRKSFTTKDDASLHLFHITTSKSPKHPCGLSEKQSTLLKQENTKTCLSP-GSSETSLQS
DLIRHENNAESEFLLETSSGKYCKHKEKSKHHQKDFHLEFGEKSIPKIKDEDHSLSFDNS
DYTLKKIDKEGKTLKKHKLKHKDREKEKHKKESDGEKEKYKNKDGNKAVQRSVEFDREFW
KENFFKTDETEDIFSNVEHEFLPSEKKSKL---EKNT-KDDRSSKEKHIPKERNFKEERE
--KGKKESEKSLKEEKIRELKEERE-NISIDKE--TELLPLGINVKEESVGLHLIEKETE
IDKQEKNMKETKDRPEKRLQLKEKELERNERKNAEKEKKIKHDHKPERDKLDFSECIEKA
KEKDRVNSQQAEKYHKESEKIKNVISVKKNDDREKNRDKMDKKHDKEKTEKERHLGESKE
KHFIEKKGKLSDKDSEYIKLEKTRTKEKEREIEKREKSRDKESLSLAASKHAQEEKRSTS
TEG-SKTLHEKLSSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNNLP
KHK---SEVDKHKFKS----SLTPKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRSSLELNKVKDKEKTKNALAESKTKELIRSKSSELSDVYTKEKH
LKDATSNRSQSVDTKNITNIGKSSLIV-DNNL--SRSPRSESEKTGLSSRSVSMVSVTSS
EDSCHTTVTTPRPIVEYDSDFILEGSDSQMSFSQSPFLPVAKSPALHERELDSVAELPER
IKLPYANRLSISHLRSS-SIEDVKLIISECRPVVEVRRCSMPPVIS-EHSKQLQ-TMSEE
NNPSSL--LAVPSHI-CNSPKHEVSSCNVPENDLSK-VSNLHSS-FATSPVTSFSSKHSS
-SDTNVIKSTSQINPIGENPMHVEPCNLINMTQQNKSWEISVDRLESLSTNDFNCSSYRV
PDQ-DPIIQGLCN--SDNKILKEQNTSELLPQHQTEIQGNSGAQDSAAF-MPSQLPCSFH
G-QSFQDA-ECIPKHMPLSYIGDNQETTFQQK----TLVQT-NSVLDT-DNFKKDLENTF
SPTDSQKTDGFISVYTERTIQDTSPNHERTNALPIVSSEKDFLGNDVYSQMNTHPYSFSK
LIYKTSQSHEVDS-TNDTQVISHEKEK-LESSVLI-I-TNKSDVDLNELNA--EISKGNL
NEQDNSKNYSESRKGFLSTEDEELQQSTLSNPESHSQPSGQGEINKGTQLVKIEIEETAE
DDKN-DHQIPQRITRNRANIMASQNKQIPISCMPLSEKDN-E-SVSPRGRIRLTEEDDAQ
VHHPRKRKMSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQTDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHSKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LGMSAIEESMGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKESEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLTESKE
KHLMEKKNKQSD-NSEYTKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFH-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSG-FAISPTGASNSKYVS
-ADRNVIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNSCAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGNDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKD

PF12796 // ENSGT00760000119090_6_Domain_0 (189, 259)

KVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEARSVNP-SSVDENIDSETEKDSLICESKQI
IPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKELRKENEAEVEKNSLFTK
PEK-AFYPKSFKSKKQKPSRVL-YSSSESSDEEILQNKKVSAPCS-VPETSNSDTQTKKE
YGISNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTINTALDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKEFHLEFGEKSNAKVKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKSI-KDDKSTKEKHVSKERNFKEERE
--KIKKESEKSFREEKIKDLKEERE-NIPIEKE--TECGSLGTNASEESIGLHSMEKEIE
MEKQEKYIKESKEKSERRFQTKEKDVEKTERKNSEKEKKIKHEHKSEKDKLDLSDCVDKI
K--DKLYSHHTERCHKESEKLKNITTVKKNDDREKSREKMDRKHDKEKPEKDRHLAESKE
KHLIEKKNKAAD-SSDYTKSEKSKNKEKDREVDKKEKSRDKEGINVTNPKHFQEEKKSST
TDS-CKAQHEKTLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEVDKPKLKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHALAESKNKELTRSKSSELTETYTKEKQ
SKDAVSNRSQSVDAKNITNLGKSSFVS-DNNL--SRSPRSESEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSDSQMSFSQSPFLPVAKSPALHERELDSLAELPER
IKPPYTSRLPTSHLRSS-SVEDVKLVINEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SSQGGL---AVPREI-CPSPKPEVS-SNVPERELSN-VSNIHSS-FAASPTRSVNSKYIS
-ADLNVIKSTAPLGTLMDNPVHLEPSNQVGV-IQNKSWEVSVDKLESLSTNDLICPNSST
PDQ-DSSVQGFCN--SENKILKEQNTD-FLSLHQTELPGNSCAQDPMSF-LPSQQPCSFH
S-QSLSDA-ESVSKPMSMSYVANQEPGIFQQK----NAVQIINSVLDTDNESTKEMENTF
VLTDVQKTDAFVPVYSENTVQEASPNFEKASTLPVLPSEKDFSGNDASSQLN-IQYTFSK
LMYKSSNGHEVENSSSDIQVIPHEKENRLESLVLTHL-NDKCDSDLCEMST--GMPKGIL
NEQDNPKHCSEGEKCLLSIEDEESQQSTLSSLENHLQQSAQPEMHKYGQLGKVELEENAE
DDKT-ENQIPQRMTRNKANTVANQSKQILASCTLLSEKDN-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQASPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPCGRKSKDKIASYSKTPKIDRSDVVKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKDAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DTTPNHPSQTTPA-QKKTP
TSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPFSDDDESYTDSEEARSVNP-SSVDENIDSEMEKDSLICESKQI
IPSKAPLP--SALDEYEFKDDDD----DEVNKMIDDRHILRKELRKENDSEVEKNSIFSK
QEK-AFYPKTFKGKKQKPSRVL-YSSSESSDEEILQNKKISTSCS-VPETSNSDLQTKKE
YVVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLMVNTALDCSEKSREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQA
DLVRYDN-TEPEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSIAKIKDEDHSPTFENS
DCTLKKIDKEGKTFKKHKLKHREREKEKHKKEFEGEKEKYKNKDGAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSRL---EKHI-KDDKLTKEKHISKERNFKEERE
--KIKKENEKSLKEEKIKDLKEERE-NVPTDKE--TELSSLGVSAKEEY-----MEKEID
IEKQEKHIRENKEKSEKRFQTKEKDTEKIDRKNSEKEKKMKQDHKSEKDKLDLNESVDKI
KEKDKLYSHHPEKCHKEGEKIKNITILKKTDDREKNREKIDRKHDX--------------
------------------------------------------SINITNSKHLQEEKKSSI
ADS-SKAQHEKFFSFKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLDPKVKDKEK-TKHILAESRNKEPIRSKSSELTDSYNKEKQ
SKDAVGNRSQSVDTKNIMNLGKSSFIS-DNSL--NRSPRSESEKLGLSSRSVSMISVASS
EDSCHTTVTTPRPPIEYDSDFMLEGSDSQMSFSQSPFLPIAKSPALHERELDSLAELPER
IKPPYANRLPTSHLRSS-SVEDVKLIINEGRPTVEIRRCSMPSLVC-EHTKQFQ-TISEE
SNQGSL--LAVPRVI-CPSPKPEVS-SNVPERDLSN-MSNMHSS-FAASPTTSVNSKYNS
-ADINVIKSTAPINTLMESPVHFEPSYQVGV-IQNKSWEGPIDRLESLSTNDFICPNSSI
PDQ-DSSCQDFCT--SENKKLKEQNTE-LLSLHQSELPGNSSAQDPACF-MPSQQPCSFQ
S-QSLSDA-ESISKHMSLSYIANQELGVLQQK----SSVHMITSVSDTDNESAKDLENSF
APADIQKTDAFVSEYSESTIQEASPNFEKANTSPELPLEKDFNGNDASSQLN-AHYAFSK
VMYKSSNGHEIENK-TDIQGISHEKENELESLVLTHL-NDKYESDLCEMNA--GIPKGNL
NEQDNPKHCPESEKCLLSIEDDESQQSTLSNLDNHSQQSAQPEMHKYGHVVKVEIEENAE
DDKT-ENQIPQRVTRNRANTMANQSKQILASCTLLSEKDS-E-FSSPRGRIRLTEDDDPQ
VHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LSSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTSLYAK
QEK-AFYPKSFKNKKQKPSRVL-YSSTESSDEEALQNKKISTTCSVIPETSNSDTQTKKE
YVVTGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKDKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEVEVEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKTI-KDEK-TKEKHVSKERNFKEERE
--KTKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFISLSMSAIEESIGLHSVEKEID
IEKQEKHIKESKEKSEKRFQTKEKDIEKERK---NFEKKIKHEHKSEKDKLDLSECVDKI
REKDKLYLHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHL-EKKNKQSD-NSEYTKSEKGKNKEKDRELDKKERSREKESINIANSKHAQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SETDKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRNCLELKIKDKEK-AKHTPAESKSKELARSKSSELSDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKSGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSESQMSFSQSPFLSVAKSPALHERELDSLADLPER
IKPPYANRIPTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSD-LSNIHSS-LAASPTGASNSKCVS
-ADRNIIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWETP-DRLDTLGTRDFICPHSNM
PDQ-ESSLVSFCN--SENKILKE-NAD-FLSLHQTELPGNSCAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHMSLTYVANQEPGILQQK----NVVQIISSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDASTQLN-THYAFSK
LTYKSSSGHEVENSTVDIQVISHEKE-KVESLVLTHL-N-RCDSDLCEMNA--AMPKGNL
NEQDSPKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMNKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTIANQNKPILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEARSVNP-SSVDENIDSETEKDSLICESKQI
IPSKAPLP--SALDEYEFKDDDD----EELNKMIDDRHILRKELRKESESEIEKNSLFAK
QEK-TFYPKSLKSKKQKPSRVL-YSSSESSDEEILQNKKVSAPCS-VPETSNSDTQTKKE
YGISNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLAVNTTLDCSEKTREEG
NFRKSFSPKDDSSLHLFHISTGKSPKHSCGLSEKQSSPLKQEHTKTCLSP-GSSETSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDGTKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLILEKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERE
--KIKKESEKSFREEKIKDLKEERE-NVPIDKE--TEFSSLGVSVSEESIGLHSMEKEIE
IEK---HIKESKEKSEKRFQAKEKDIEKTEKKNSEKEK-KKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKIKNITAIKKADDREKSREKIERKHDKEKSDRERHVAESKE
KHLMEKKPKQLD-NSDYTKSEKSKN--KDREIDKKEKSREKESVNITNSKHFQEEKKSSI
ADS-SKAQHEKTLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHALAESKNKELIRSKSSELTDAYTKEKQ
SKDAISNRSQSVDTKNIMNLGKSSFVS-DNSL--NRSPRSESEKLGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSDSQMSFSQSPFFPVAKSPALHERELDSLAELPER
IKPPYTSRLPTSHLRSS-SIEDAKLVISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQSGL---AVPRDI-CPSPKPEVS-SHVPERELSN-VSNVHSS-FAASPTRSVNSKYVS
-ADINVTKSTAAVSTLMNSPVHLEPSNQVGV-IQNKSWGIPVDRLESLSTSDFISPNSST
PDQ-DSSVQGFCN--SENKILKEQNTD-FLSLHQTEPPGHSCAQDPPSF-LPSQHPCSFH
S-QSLSDT-ESVSKHVSLSSVANQEPGILQQK----NAVQIISSALDS--ESAKDMENTF
VLTDVQKTDAFVPVYSESIVQEASPNFEKANTLPVLPSEKDFSGSDASSQLS-TPYAFSR
LMYKSSGSHGVENSTSDIQIISHEKESKLESLVLTHL-NDKCDSDLCDMNA--GMPKGNL
NEQDNPKHCPESEKCLLSIEDEESQQSTLSSLENQSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTVASQNKQILASCALLPEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSIIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDSSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-AESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFTSLGMSAIEESIGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-NSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSEVTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSS-FATSPTGASNSKYVS
-ADRNLIKNTAPVSTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLRQTELPGNSCAQDPASF-MPPQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQIISSALDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDTQVISREKEDKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPAFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LGMSAIEESMGLHLVEKEID
VEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECADKI
KEKDRLYSHHTEKCHKESEKSKNTATIKKTDDREKSREKMDRKHDKEKPEKERHLTESKE
KHLMEKKNKQSD-NSEYTKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDNRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTQTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSG-FAISPTGASNSKYVS
-ADRNVIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNSCAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDAENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGNDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKE-KLEGLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFTSLGMSAIEESIGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-NSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQINSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSEVTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSASHLRSS-SVEDVKLIISEGRPTIEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LIVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSS-FATSPTGASNSKYVS
-ADRNLIKNTAPVSTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDYICPNSNI
PDQ-ESSLQSFCN--PENKILKE-NAD-FLSLRQTELPGNSCAQDPASF-MPPQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQIISSALDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDTQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSTQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTQKIDRSDAGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKESLICESKQI
VPSKAPLA--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENESEPEK-SLFAK
QEK-AFYSKSFKSKKQKPSRVL-YSSTESSDEEVVQSKKISAASS-VPETSNSDTQTKKE
YE----YKQKGKVKRKLKNQSKNKENQELKQEKEEKENTRVTNLTVNAALDCSEKTREEG
NFRKSFSPKDDSSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPEGSSVKSYKHKEKNK-HQKDFHLEFGEKSNAKIKDEDHNPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKETEGEKEKYKNKDGVKELQRSMEFDREFW
KENFFKSDETEDLFLNMEHESLT-EKKSKL---EKSI-KDEKSTKEKHVSKERNFKEERE
--KIKKENEKSFREEKIKDAKEERE-NVPTDKE--IEFTSLGISINEESVGLHSMEKEID
VEKQEKHIKESKEKSEKRFQTK--DVEKTERKNSEKEKKIKHEHKSEKDKLDFSECVDRI
KEKDKLYSHHPEKCHKEGEKIKNA--TKKTDDREKSREKVERKHDKEKPEKERHLTESKE
KHLIEKKSKQSD-NTEYTKSEKGRNKERDRELDKKEKSRDKEG--ITNSKHVQEEKRSSM
MDS-CSKAHEKTSSLKDKTKDEPLKTPDGKEKDKKD--RDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHGLAELKNKELTRSKSSELTDTYTKEKQ
SKDAVSSRSQSVDTKTVTSLGKSSFVS-DSSL--NRSPRSEGEKPGLSSRSISMISVASS
EDSCLTTMTTPRPLAEYDSDFMLEGSESQMSFSQSPFLPIAKSPALHERELDSLAELPER
IKLTYANRLPATHLRAS-SVEDVKLIINEGRPTVELRRCSMPSVIC-EHIKQFQ-TTSEE
SNQGS---LAVPRDN-CPSSKSEVS-SNVPERDLSN-VSNIHCS-FTASPASSANSKYIS
-DDVNVIKSTGPVATLMDSPVHLDPSSQVGV-TQSKSWEIPVDRIESLSTSDFICPNSGT
PDQ-DFSVQGFCN--PENKILKEQNTE-YLSQPQTELPGNSCAQDPVSL-LSSQQPCSFP
S-QSLSDTSDTVTKHVSLSYVATQELGILQQK----DAVQMISSVSDIDNDSTKDVENTF
VLADVQKTDNFVPVYSESTIQEGSSNFEKASMLPVFPSEKDFTGSDGHSPLN-TH-AFSK
LTYKSSSSYEFENSTTDTQVILHEKENKLECLFSTHL-N-KYDPDLCEMNT--GMPKGNL
NEQDNPK-CPESEKGLLSIEDEESQQSTLSSLENHSQHSAQPEMNKYGQLVKVELEENAE
DDKT-ENQIPQRMTRTKANTMANQSKQILASCALLSEKDS-D--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDNKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGVTKPVQSENSDSDS-NMVEKPCGRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXKEGPEKKKARKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQATPT-QKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPVSDGEETYTXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX--XXXXEYEFKDDDD----EEMNKMIDNRHILRKELRKENESEIEKNNLFAK
QEN-AFYLKSFKNKKQKSSRIL-YSSSESSDEEILQNK--VTTPCSAPEPSNSDMQTKKE
FVISNEYKHKGKVKRKLKNQNKNKENQELKHEKEEKENTRVTNSTVNTALDFSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQS------------------EMSLQS
DLVRYDN-TESEFLPESSSVKSCKHKEKNK-HQKDFHLEFGEKSSVKIREETHSATFENS
ECTLKKMDIEGKTLKKHKLKHKEREKEKQRKETEGENEKHKNKDGAKELQRNVEFDREFW
KENFFKSDEPEDLLLNMEHETLTLEKKIKL---EKNM-KDDRLTKEKYSSKEKNFKEERE
--KIKKESEKSFREEKMEDLKEERE-TVSTSRE--TEFNSLDISAKEEPS--FSIGKEID
IEKQEKYIKE---KSEKRFQTKEKDIEKAEKKLPEKEKHIKCDHKSERERLDMSECADRG
RDKDKLYPHHTEKCSKENEKIKNITAIKKTDERKKIREKMDRKYDKETPEKERTLTENKE
KYLMEKKNKQSD-NSEYIKSEKGKIKEKDRDVDKRGKSRDKESITITNHKQLXXXXX-XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX
XXX---XXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXKERLRNRNCLELK-VKDKEKTKHVLIKSQTKELSRSKSSELTDAFSKEKH
PKEATSNRSQSLDNKNIMNLGKLSFVS-DTSL--NRSPISEREKPDVSSRSTSMTSAAGS
EDCCHTTVTTPRPPQEYDSDFMFEGSDSQMSFSHSPFLLLTKSPALHEREVEGLAEAPER
IQSTCANRLPSSHLRS--FVEDIKLITNEFKPSVEVGRCSIPSVIC-EHTKQSP-AIAEE
SHQRTL--LVVPKAI-CSSPKPKV-SSNVPESDLSN-ISNILSS-LTVSPTRTVNSKCNL
-GDTNVIKSTAAISSLIGDPVHLEMSNQVHVIQ-SQSWEIPVDRLESLSTSDLTCPNSGT
LDQ-DSSGQGFCH--SENKIVKEQNSGFSFPHQ-TELPGKSCAQDPASF----------H
S-QSLADA-ESTSKHVSLSYVAYQQPVILQQK----NSVQTISSVLDTDNESTKEIEN--
-PADIPETDAFVSVYSETTVQEASPTVEKANALPMLPSKRDFHGNDASSQLCTH-ILFNQ
LLSKSSSSFEVESSTTDIQVISHDKGNKLESFILTHL-NDKYDSDFCDKNE--RIPKTHT
NEQDNPKYWTGNEKCLRSIQDEESEQSTLTNLGNHPQQSVPSEIHKFGQFVKVELEETAE
DDKI-ENQIPQRVTRNRTNTLVNQSKHFLASCTLVSEKDN-E-SSSPRGRIRLTEEDDPQ
VHHPRKRKV----------------------SLAAIVDSLKLDAIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
DLFQQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKASVRDRFNARQFMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXSIY-EQEFYVPLGDVNDDFQLTPV

MPKSGFTKQVQSENSDSDS-NMVEKPYGRKSKDKIGSYSKTPKLDRNDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDT------------------------EKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPT-QKKTP
NS-SRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGDPFQANKHGERPV
DVAETEELELLLKREVPLSGDDEIYTDSEEARSVNP-SSIDENIDSETEKDSLTCGSKQN
VPSKGPLP--SALDEYEFKDDED----EDVNKIIDDRHILRKEQRKENDCEAEKSSLFTK
QEK-IFYAKSFKNKKLKPSRVL-YSSTESSDEEVLQNRRVSTACS-VPETSNSDAQTKRE
YE----YKHKG-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

MPKSGFTKPVQSENSDSDS-NMVERPYGRKSKDKIASYSKTSKIDRSDMGKEMKEKSSMK
RKLPFAISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-S
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAHSVNP-SSVDENIDSETEKDSFICESK-V
LPSKAPLP--SALDEYEFKDDDE----EEISKMIDDRHILRKEQRKDNESEAEKSGLFAK
QEK-TFYSKSFKTKKQKPSRVL-YSSTESSDEDVLQNKKISTSCS-VPETSNSDMQAKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTALDCSEKTREEG
NFRKSFSPKDETSLHLFHISAGKSPKHSCGLSEKQSTPLKQEHTKACISP-GSSELSLQP
DLVRYDS-TETEFLPESSNVKSYKHKEKNK-HQKDFHLEFGEKSNAKLKDEDHNPAFENS
ECTLKKMDKEGKTLKKHKLKHKEREKEKHKKEVEGEKEKYKNKDNAKELQRSIEFDREFW
KENFFKSDETEDLFLNMEHESLT-EKKSKL---EKNM-KDDKLPKEKHVSKERNFKEERE
--KTKKENEKFLREEKL---KEERE-SVSTEKE--AECSSVGASINQESVGPHSVEKEMD
IEKQEKHTKE-REKSDRRFQTREKEGDKTERKFSEKEKKMKHEHKSDKEKLDFSECADRI
KEKDKLCPHQTERCQKEGEKMKNM--IKKTDDRERNREKTDRKHDKEKPEKDRCLAESKE
KHLEK---KKSD-NSEYIKSEKVRS--KDREGEKKEKFRDKESMNISNSRHLQEEKRSSI
GDSSSKIQHEKTMSLKEKARDEPLKTPDGKEKDK----KDIDRYKERDKRKDKIQLNPLL
KLK---SETDKPKPKS----LPVSKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRSCLELKVKDKEK-TKHIPTESKNKEFTRSRSSELTDVYNKEKH
SKDVGSNRSQSVDTKNVLSLGKSAFIS-ENSS--NRSPRSESERLGLSSRSVSMISVASS
EDSCHT-VTTPRPLVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELESLTELPER
LKPPCTNRLPVCHLRSS-SVEDVKLITNEVRAAVEIRRCSMPSVIC-EPTKHFQ-IA-EE
SNQ-GS--LAVPRET-CPSPKPEVS--PMPERGLSH-LSDLNPN-FTGSPTRTINSRYIS
-TDTNVIKSAGVVGTLVDSPMHLEPSNQVGV-IQNKSWEMPVDKLESLSTNEFICPDSGT
VDQ-DSSAQSFCN--SENKMLREQSTD-CLSLHQTELPGNSCAQDPASF-LSSPQPCSFS
N-QSQSDA-ECASKPVSLSYAANQEPGILQQK----NAAHMISSVIDNDSNFTKDVENTF
VLADIQKTNSFVPVYSESTIQETLPAFEKANTLLVLPSEKDFSGSDAASQIS-THYAFSK
LTYKSSSSHDIEKSMDDA-HVSHEKESKLQSLVLTQL-S-KCDSDLYEMNA--GMPKGSL
NEQDNPKHGPDSEKYLLSIEDEESQQSTLSGVESHSQQSAQPEMHKYDQLIKGELEESAE
DDKT-ENQIPQRMTRNKSSTMVNQSKQILAGCTLLPEKDS-D--SSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIESEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LGMSAIEESMGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKESEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLTESKE
KHLMEKKNKQSD-NSEYTKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHTPTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSLNLNRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSS-VSNIHSG-FAISPTGASNSKYVS
-ADRNVIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNSCAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGNDSSTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKPGFTKAIQSENSDSDS-NMVEKPYGRKSKDKIASYSKTQKIDRSDVGKEIKEKSSMK
RKLPFTISPTRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKESLICESKQV
VPSKAPLP--SALDEYEFKDDDE----EEINKMIDDRHILRKEQRKENDSEAEKSSLFTK
QEK-AFYSKSFKSKKQKPSRVL-YSSTESSDEEVLQSKKISTASC-VPETSNSDTQTKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNAALDCSEKTREEG
NFRKSFSPKDDSSLHLFHISTGKSPKHSCGLSEKQSAPLKQEHTKTCLSP-GSSEM-LQP
DLVRYDN-AESEFLPESSSVKSYKHKEKNK-HQKDFHLEFGEKSNAKIKDDDHNPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHRKEIDSEKEKYKNKDGAKELQRSVEFDREFW
KENFFKSDETEDLLLNMEHESLTLEKKSKL---EKSV-KDEKSTKEKHVSKEKNFKEERE
--KIKKENEKSFKEEKVKDLKEERD-SIPTDKE--IEFSSLGISVNEESVGLHSLEKEID
TEKQEKHTKESKEKSEKRFQTK--DIEKTERKSSEKEKKIKHEHRSEKDKLDFSECVDRI
KEKDKLYSHHPEKCHKEGEKTRNT--LRKTDDRERSREKMERRHEKEKPEKERHLAESKE
KHITEKKSKQLD-NTEYTKSEKGRSKEKERELDKKEKARDKEG--ITNSRHLQEEKKSGM
IDSYSKTQHEKIFSLKDKTKDEPLKTPDGKEKDKKD--RDIDRYKERDKHKDKIQLNSLL
RLK---SEVDKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK--KHGLAEPKNKELTRSKSSELTDTYTKEKQ
AKDAVSGRSQSVDTKNVMSLGKSSFVS-DSIL--NRSPRSEGEKPGLSSRSVSMISVASS
EDSCHTTMTTPRPLAEYDSDFMLEGSESQMSFSQSPFLPVAQSPALHERELDSLAELPER
IKPPYANRLPASHLRAS-SVEDVKLLISEGRPTVEVRRCSMPSITC-EHSKQFQ-TSE-E
SIQ-GS--LAVPRDN-CSSPKPELS-SNVPERDLSH-VSNIHSC-FTASPTRSANSKYIS
-ADGNVIKSTGPLGTSVDSPVHFEPSNQVGV-IQSKSWEIPVDRLEPLSTNDFICPNSST
SDQ-EFSVQGFCN--PENKILKEQNSE-FLSLHQTELAGNSCVQDPVSF-LSSQQPCSFP
N-QSLSDA-DSVSKHTSLSYVAAQELGILQQK----DVVQMITSVSDTDNESTKDVENTF
VLADVQKADTFIPLYSENTIQEASPNFEKATVLPVLQSEKDFNGSDGLSQLS-TH-SFNK
LTYKSSSSHEVESSAADIQVISHEKENKLESLFSAHL-N-KYESDLCEMNT--GMPKGNL
NEPNP--KRPESEKCLLSIEDEESQQSTLSSLENHPQHSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQNKQILASCALLPEKDS-D--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEARSVNP-SSVDENIDSETEKDSLICESKQI
IPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKELRKENEAEVEKNSLFTK
QEK-AFYPKSFKSKKQKPSRVL-YSSSESSDEEILQNKKVSAPCS-LPETSNSDTQTKKE
YGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTALDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKVKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLT-EKKSKL---EKNI-KDDKSTKEKYVSKERNFKEERE
--KIKKESEKSFREEKIKDLKEERE-NIPIDKE--TECSSLGTNASEESIGLHSMEKEAE
MEKQEKHIKESKEKSERRFQTKEKDVEKTERKNSEKEKKTKHEHKSEKDKLDLSDCIDRI
KEKDKLYSHHTERCHKEGEKIKNTTTVKKTEDREKSREKMDRKHDKEKPEKERHLAENKE
KHLIEKKNKQAD-NSDYAKSEKSKN--KDREVDKKEKSRDKEGVNITISKHFQEEKKSSI
ADS-SKAQHEKTLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKLKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKEKEK-TKHVLAESKNKELTRSKSSELTDAYTKEKQ
SKDAISGRSQSVDAKNITNLGKSSFVS-DNSL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSDSQMSFSQSPFLPVAKSPALHERELDSLAELPER
IKPPYTSRLPTSHLRSS-SVEDVKLVINEGRPTIEVRRCSMPSVIC-EHTKQFQ-TISEE
SSQGGL---AVPRDI-CPSPKSEVS-SNVPERELSN-VSNIHSS-LAASPTRSVSSKYIS
-ADINVIKSTAPVGALMDSPVHSEPSNQVGV-IQNKSWEVPVDRLESLSTSDLICPNSST
PDQ-DSSVQGFCN--SENKILKEQNTD-FLSLHQAELPGNSCAQDPASF-LPSQQPCSFH
S-QSLSDA-ESISKHMSMSYIANQEPGILQQK----NVIQIINSVLDTDNESAKEMENTF
VLSDVQKTDAFVPVYSESTVQEASPNFEKANTLPVLPSEKDFSGSDASSQLN-THYTFSK
LIYKSSSGHEVENSTSEFQVISHEKENKLESLVLTHL-SDKCDSDLCEMST--GMPKGNL
NEQDNPKHCPEGEKCLLSIEDEESQQSTLSSLENHLQQSSQPEMHKYGQVGKVELEENAE
DDKT-ENQVPQRMTRNKASTVANQSKQILASCTLLPEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKNP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEARSVNP-SSVDENIDSETEKDSLICES---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------KSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKNK-HQKDFHLEFGEKSNAKVKDEDHSPTLENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDSAKELQRSVEFDREFW
KENFFKSDETDDLFLNMEHESLT-EKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERE
--KIKKESEKSFREEKTKDLKEERE-NIPIDKE--TECSSLGTNASEESTGLHSMEKEIE
MEKQEKHIKENKEKSERRFQTKEKDVEKTERKNSEKEKKTKHEHKSEKDKFDLSDCVDRI
KEKDRLYSHHSERCHKEGEKIKNITTVKKTDDREKSREKIDRKHDKEKPEKERHLAENKE
KHLIEKKNKQAD-NSDYTKSEKSKNKEKDREVDKKEKSRDKEGVNITNTKHIQEEKKSSI
ADS-SKAQHEKTLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KVK---SEADKPKLKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHSLAESKNKELTRSKSSELTDAYTKEKQ
SKDVVSNRSQSVDAKNITNLGKSSFVS-DNSL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSDSQMSFSQSPFLPVAKSPALHERELDSLAELPER
IKPPYTSRLPTSHLRSS-SVEDVKLIINEGRPTVEVRRCSMPTVIC-EHTKQFQ-TVSEE
SSQGGL---AVPRDT-CLSPKSEVP-SNVPERELSN-VSNIHSS-FAASPTRSVSSKYIS
-ADINVIKSTAPVGTLMDSPVHLEQSNQVGV-IQNKSWEVPNDRLESLSTGDLSCPNSSA
PDQ-DSSVQGFCN--SENKILKEQNTD-FLSLHQTELPGNSCAQDPVSF-LPSQQPCSFH
S-QSLSDA-ESVSKHMSVSYVANQELGIAQQK----NAVQIMNSVLDTDNECTKEMENTF
VLTDVKKTDAFVPVYSESTVQEASPNFEKANTLSVLPPEKDFSGSDASSQLN-THYTFSK
LMYKSSSGHEVESSTSDIQVISHDKENKLESLVLTHL-NDKCDSDLCEMST--GMPKGNL
NDQDNPKHCPEGEKCLLSMEDEESQQSTLSSLENHLQQPAQPEMHKYGQIGKVELEENAD
DDKT-ENQIPQRMTRNKANMVANQSKQILASCTLFSEKDN-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEDRDSDTDSEPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--ESTPNHPSQTTPA-QKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHKDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDGDESYTDSEEARSVNP-SSVDENIDSETEKDSLISESKQI
IPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKELRKDNESEVEKNSLFTK
QEK-AFYPKSFKTKKQKPSRVL-YSSSESSDEEILQNKKCPVPCS-VPETSNSDTQTKKE
YGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNPALDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTSKSPKHACGLSEKQSTPLKQEHSKACLSP-GSSEMSLQS
DLVRYDN-TESEFLPESSSVKSCKHKEKNK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDGTKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHEALTLEKKSKE---KNXX-XXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-XXXX-XXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX
XXX---XXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEKQ
SK-DVSNRSQSVDTKNTVNLGKSPIIS-DSSL--NRSHRSESEKPGLSSRSVSMIFSSSS
EDSCHDAVTTPRPPVEYVSDFMLEGSDSQMSFSQSPFLPVAKSPALHEREPDSLAELPER
VKAPHTSRLPASHLRSS-SAEDVKLVLSEGRPAVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQDG---LAVPRVT-CPSPQTEVS-SPVPERELSN-VSNVHSS-FAASPTRSVNSKYTS
-ADVNVVKSTAPVGPLTDSPVHLEPSNQVDV-IQNKSWEIAVERLESLSTSDFICPSSRM
PDQ-DSSVQGFCN--SENKILKEQNTD-FLSLHQTELPGNTCAQDPASF-LPSQQPCSFH
S-QSLSDAES-ISXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX--XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXANPYFEYL
HIWKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLR-QHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSLSIYEIQEFYVPLVDVNDDFELTPI

------------------------------------------------------------
-------------------------------------------EKEGPEKKKMKKDAG-N
KKSAPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTLNHSVQTTPT-QKKTP
TSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELIRLGANVNVKDFAG----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

MPKPGLPKPAQSESSDSDS-NMVERPCGRKSKDKIASYSKTSKIDRSDTGKEMKERPSMK
RKLPFTISPSRNEERGSDTDSDPGHTSENWGERLVSSYRT-YAEKEGPEKKKTKKETG-S
KKSTPVSILFGYPLSERKQ------MALVMQMTARDNSP--DSTPSHPSQATPA-QKRTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGADVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAHSVNP-SSVDENIDSEPEKDPFVCESK-V
LPSKAPLP--SALDEYEFKDDDE----EDISQMMDDRHILRREQRKENESEAEKSGLFAK
QEK-AFYSKSFKTKKQKPSRVL-YSSTDSSDEDLLQGSKRTSAACSVPEPSNTDTQARRE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRVTNLTVNTALDCSEKTRDEG
SFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHMKACISP-GSSELSLQP
DLARYDS-MEPEFLPESSNVKSYKHKEKNK-HQKDFHLEFGEKSNAKMKDEDHNPTFENS
ECTLKKMDKEGKTLKKHKLKHKEREKEKHRKEADGEKEKHKGKDSARELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLT-EKKSKL---EKSM-KDDKSSKEKHASKERGFKEERE
--KTKKENEKSLREEKLKEE---R-DSVSTERE--AECSSVGVTVNQESAGPHSAEKEMD
IEKQEKHTKE-REKSDRRFQTKEKEVDKMERKLSEKEKKIRHDHKSEKEKWDFSECVDRI
KEKEKLCLYQTERCQKEGERMKST--IKKADDRERNREKMDRKHDKERPEKERCLAESKE
KHLEKK---KSD-NSEYAKSEKARN--KDREGEKKEKFRDKESINVTNSRHLQEEKRSSI
GDS--KIQHEKTVCLKEKARDEPLKTPDGKEKDK----KDIDRYKERDKRKEKIQLNTLI
KLK---SETDKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRTCLELKVKDKDK-TKHTTNESKNKEFSRSRSSELTDVFNKEKH
SKDVGSNRSQSVDTKNVLNLGKSSFIS-ENTS--NRSPRSESERLGLSSRSVSMISVASS
EDSCHT-VTTPRPPVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELESLADLPER
LKPPCTNRVPVCHLRSS-SVEDVKLIPNEVRPAVEIRRCSMPSVIC-EPTKHFQ-IPEE-
-NTQGS--IAVPRET-CPSPNSAVS-SAVPERGLPP-GSDFHPN-LTGSPAMSVSNRHIA
-SDTNVIKSVGLAGTLMDSPVHLEPSNQVGV-IQNKSWEMPADKLESLSTNDFICPDPST
SDQ-DSSAQSFCN--SENKRLREQNTD-CLSSHQTEMPGNSCTQDPASF-LSSLQPCSFS
N-EAHSDA-ESASKSVSLSYGASQDTGILQER----NAGPVISSVLDSDNNFTKDVENTF
VLADIQKTNSFVPVYSENPVEETLPSFEKASTVLVLPSGKDLSGSDTAAQVS-TQYAFSK
LTHKSSSSHEVEKSMDDTQVVSHEKESKLQGLVLTQL-S-KCDSDLYGMNA--GVSKGSL
SDQDAAKHGHSGEKYLFPVEDEESQQSPLSSVDSHSQPSAQPEMHKYDQLTKGELEESAE
DDKT-ENQLPQRLTRNKVSTVVGQSKQILAGCTLLPEKDS-D--SSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIER---------------------------------------
-----------------------------------------TCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYNKTPKIDRSDVSREMKEKSSMK
RKLPFTVSPSRNEERDSDTXXXXXXXXXXXXXX-XXXXXXXXXXKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSPXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

XXWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 277)

DDDTPLHDSASSGHRDXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPNKAPLP--SALDEYEFKDDDX----XXXXXXXXXXXXXXXXXXXENESETEQ-SMFAK
QAK-TFYSKSFKSK-QKPSRVL--SSTESSDEEILQNKKISTSCC-IPETSNSDTQTRKE
FVFPSEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRIMNLTVNPALDCSEKTREDG
SFRKSFSPKDEASLHLFHISTGKSPKHSCGLSEKQSTAPKQEHMKTCLSP-GSSEPLLQP
DLSRYGN-TDPELLPESSNAKSCKHKEKNK-HQKEFHLELGEKSNAKIKDEDHNPAFETS
DCTLKKMDKEGKTFKKHKLKHKEREKEKHKKEAEDEKEKYKTKDGAKEIQRSVEFDREFW
KENFFKSDEAEDLFLNMGHESLLLEKKSKL---EKNV-KDDKSTKDKHVSKERNFKEDRE
--KVKKENERPFREEKLKE---ERE-NVLIDKE--TEFSSLSVSANEESVVLHSAEKEVD
TEKQEKHIKESKEKSEKRFQTKEKDAEKTERKNSEKEKKTKHEHRSEKDRPDLSDSIDRV
KEKDRLYSHHTEKCHKEGEKTKSIT-LKKTEDREKSREKMD-KHDREKSEKERQLAESKE
KHLMEKKNKQLD-NSEYTKSEKGKSKDKDREAEKKEKSRDKESTSTFNAKHLQEEKKSSV
VDS-SKAPHDKTLSLKEKTRDEPLKTPDGKEKDK----KDIDRYKERDKH--KIQLNSLF
KLK---PEAEKPKP------SPAAKDARPKEKRLVDDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKDK-TKHTLAESKSKDLSRSKSSELTDSSTKEKQ
SKDAVSSRSQSVDTKTSVNLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPLVEYDSDFMLEGSESQMSFSQSPFLSVAKSPALHERELDSLAELPER
IKTPYASRLQTSHLRSSSSVEDVKLVISEGRPTVEVRRCSMPSVIC-EYPKQFQ-TVSEE
SNQGSL--LVVPRDI-CPSPKLVVS-SNVPEKDPLH-VSHIHSS-CTASPTGSVSNRYIS
-ADINVIK---SVGTVIDSPMHLEPSNQVGV-IQNKSWEIPGDRLESLSTSDSVCPDASI
PDQ-DSSVQGFSN--SDNKMVREQNAE-FLSLHQTELPGNSYSQDPASF-LPSQQPC-FP
S-HPLSDV-ESLSRHMSLSYVASQEPSILQQK----NIVQVISSVLDNDNESVKDGGSNF
VL-DAQKPDAFVTVYSESAAQEATPNSEKANTLPVVLSAKDLKGSDAASQLT-THYALSK
LTYKSSSG-EGENGTTDVQVVSQERE-KLESLVLTHL-S-KCDSDLCEMNE--GMPKGNL
SEQGNPKHCLESEKCLLSVDDEESQQSSLSSMENHLQQSAQPGLHKYDQLVKVELEENTD
DDKT-ENQIPQRMTRNKANTLTSQTKPILTSCMVLPEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKDAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELIGLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICDSKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENESEAEKNSLFAK
QEK-TFYPKSFKSKKQKPSRVL-YSSTESSDEEVLQNKKISSSCS-VPETSNSDIQTKKE
HLVSSEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTALDCSEKTREEG
NFRKSFSPKDDASLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TEPEFLPESSSVKSCKHREKNK-HQKEFHLDFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEKEKEKHKKETEGEKEKYKNKDGVKELQRSVEFDREFW
KENFFKSDENEDLFVNMEHESLTLGKKSKL---EKNM-KDDKSIKEKHISKEKTFKEERE
--KIKKESDKSFREEKIKDLKEERE-NVPTDKE--AEFSSLGLSTSEESIGLQSVEKEID
IEKQEKHIKESKEKSEKRFQIKEKDVEKAERKSFEKEKKVKHEHKLEKDKLDLSDCVDRI
KEKDKLYSHHTDKCHREGEKIKNIT-IKKTDDREKSREKMERKHDKEKTEKERHLMESKE
KHLEKK--NKSD-NSEYNKSEKVKNKEKDREVDKKEKSKDKESINITNSKHLQEEKKSSI
GDS-SKVQYEKSLSLKEKTKDEPLRTPDGKEKDKKD--KDIDRYKERDKHKDKIQLSSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCSEVKVKDKEK-TKHTLAESKNKELTRSKSSELTDAYTKEKQ
SKDIVSNRSQSVDTKNTVNLGKSSFVS-DSSL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSESQMSFSQSPFLPIAKSPALHEREFDTLTDLPER
IKPPYASRLPASHLRSS-SVEDVKLIISEGKPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSS--LPVPRDT-CLSPKPEVF-SNVPARDLSN-VSNIHS-----SPTRSISSKYVS
-ADINAIKSTALMGTIMDSPVHLEPSNQVGV-IQNKSWEIPVDRLESLSTRDFICPNSNT
PDQ-DSSVQGFCN--SENQILKE-NAD-FLSLHQTEPPGNSCAQDPASF-LPSQQPCSFP
N-QSPSDA-ESVSKHTSLSYVANQEPGVLQQK----NAVQIISSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSENTIHEASPNFEKANTLPVLALEKDFNGSDASTQLN-THYAFSK
LTYKSSSGHEAEISTTDIQVISHEKE-KLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQDNPKHCPESEKCLLSMDDEESQQSILSNLENHSQQSAQQEIHKYGQFVKVELEENAE
DDKN-EHQIPQRMTRNKANTVANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQ---------------------------------------------------
------------------------------------------

------------------------------------------------------------
-----------------------------------------FPEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHSLQ-TPA-QKKTP
NSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDAKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 289)

DDDTPLHDSASSGHRDIVKLLLRHGGNAFQANKHGERPV
DVAETEELELLLKREIPLSDDEEIYTDSEGAPSVNP-SSVDENIDSETEKDSLVCESKQA
IPSKASLS--SALDEYEFKDDDED-DDVEINKMIDDRHLLRKELRKEEECEMDKSNLFMK
QEK-TVFPKSFKGKKQKPSRVL-YSSSESSDEEI-QDKKIAAIPCSTPETSNSDTRTRKE
YIVSSELKQKGKVKRKLKNPNKNKENQELKQEKDGKENTRISNLVGCPALESLERTKDEE
SFRKSFSPKDETSLQLFELPAEKSSKLACGFSEKQSTALKQENPKMCLSP-SSSEMSLQS
DHVRYDNNIESEFLLESSSGKPCKHKEKVK-HQKDFHLEFNEKSSPKTKEEDPSPAFENS
DCMFKKFDKEGKALKKHKLKHKERDKDKHRKEQDVEKEKNKHRDSVKEVQRNVEFDREFW
KENFFKSDETEDLFLNMDHESLSSEKKLKV---EKT--KDDKTTKDKNIPKERGFKDERE
--KTKRENEKSLKEEKIKDLKEERE-NLATDKE--TEFSFLSTSAKEESGGFHLIEKEIE
MEKQEKSLKENKDRSEKRPQNKEKDHEKMDRKNIEKEKKVKHDHKPEKDKLEVIECIEKS
KEKDKN-LQQTEKCLKESDKIKNIP-IKKPDDKERSRDKTDKKHDREKPERERHSGDSKE
KHSSDKKVKSSEKDNDYIKLDKGKSKEK--EVEKRERVRDKESLVIVNSKHMQEEKR-LN
IAESSKTFHEKLFPLKEKPKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKTQVNNLL
KLK---SEADKPKLRA----SPAPRDIRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRSILDLK-MKEKERAKYSLSDMKNKELIRSKSSELSEAYNKEKQ
SKDATRNRSQSVDTKTITNLRKAPLVS-DNSL--NRSPRSESEKASLSSRSVSMISIASS
EDSCHTTVTTPRPMVEYDSDFMLEASDSQMVFTQAPFLPTAKSPALLERESVGTAELSDQ
MKPSFANRLPLPYVRSS-SVEDGKPVINEPRPIVEVRRCSMPSVVS-EQSKQFQ-TVSEE
-NPSVL--LTVPGHM-CISPKPEMCACSMSEKDFSN-MPNLHSS-YTSSPTRP--GKYIS
-SDSNLFKNTAQMSPLAESPMPPELCSQSSIAQPNKPWDVAFGRLESLSTSDLNCSSYRV
SEQ-NLASHGLCN--SENRTVKEQSVSELLPQHPTELLGNSCSQEAASY-LPSQPPCSFH
I-QAVSEL-ECLSKHVSLSGSGNHGSVFVQQL----NSVQAISSDLDSVPDPSKGIENTV
FPTDIKRTDSFVTLYSENAVEDAAPHFERTSSLPALQSEKDFPLSDGCPQLSVPPIVFSK
LLYKTSQVPE-EDNTVVTQIIPNERENKPEHVISTHSSSNKPDF---DLYA--GVPKGNL
SEPANQKYYSLTGQGMVSIGNDDPSQVTLLNLESNSPHLIQPEEHKCNLPSRPEVEEHAE
-----HHQTTPRVTRNRANVIANQNKQIPTSCLPLSEREN-E-SASPRGRIRLTEEEDAQ
IHHPRKRKMSRVPQPVQVNPSLLQAKEKTQQSLAAVVDSLKLDEIQPYSSERANPYFEYL
HIRRKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDQLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLESQVDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVEVNDDFELTPI

MPKSGFTKPIQSENSDSDS-NMVEKPYGRKSKDKIASYSKTQKIDRSDVSREMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPMSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKVLITAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAHSVNP-SSVDENIDSETEKESLICESKQI
GPSKAPLP--SALDEYEFKDDDE----EEINKMIDDRHILRKEQRKENESEPEKSSLFAK
QEK-AFYSKSFKSKKQKPSRVLLYSSTESSDEEVPQSKKISTV-SSVPETSNSDTQTKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTALDCSEKTREEG
NFRKSFSPKDDSSLHLFHISTGKPPKHSCGLSEKQSAPLKQEHTKTCLSP-GSSEMSLQP
DLLRYDN-AESEFLPESSSVKSYKHKEKNK-HQKDFHLEFGEKSNAKIKDEDHNPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEVDSEKEKYKNKDSTKELQRSVEFDREFW
KENFFKSDETEDLLLNTEHESLI-EKKSKL---EKNI-KDEKSTKEKHVSKEKNFKEERE
--KIKKENEKSFREEKIKDSKEEKE-SIPTDKE--MEFSSLSINVNEESVGLHSMEKEID
TERQERHIKESKEKSEKRFQTK--DIEKTERKNSEKEKKIKHEHKLEKDKLDFSECVDRI
KEKDKLYSYHSEKCHKESEKIKNT--IRKTDDRERSREKMERRHDKEKPEKDRHLTESKE
KHLIEKKSKQSD-NTEYIKSEKGRSKEKDRELDKKEKARDKEG--ITNSKHLQEEKKTNI
LDSYSKAQHEKTLSLKDKTKDEPLKTPEGKEKDKKD--RDIDRYKERDKHKDKIQLNSSL
KLK---SDADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRNCLELKVKDKEK-IKHGLAEPKNKELTRSKSSELTD-YTKEKQ
SKDTVSGRSQSVDTKNT-SLGKSSVVS-DSSL--NRSPRSEGEKPGLSSRSVSMISVASS
EDSCHTTMTTPRPLAEYDSDFMLEGSESQMSFSQSPFLPIAKSPVLLERELDSLAELPER
IKPPYANRLSASHLRAS-SVEDVKLLINEGRPTVEVRRCSMPSVIC-EHIKQFQ-TSE-E
SNQ-SS--LTVPRDN-CPSPKPQLS-SNVPERDLSD-ASNMHSS-FTASPTTAASSKYIS
-ADVNVIKSAGTLGTLMDSPVHLEPSSQVGV-IQTKSWEIPMDRLEALSTGDFICANSST
SDQ-DFSVQGFGN--PENKILKEQNSE-FLSLHQTELPGNSGVQDPVSF-LSSQQPCSFP
N-QSLSDA-DSVSKHISLSYVATQELDILQQK----DAVQVIGSVSDTDNDSTKDVENTF
VLADVQKADTFIPVYSESTIQEASPNFEKPSMLHVLPSERDINGSDGLFPPN-AH-AFNK
LTYKSSSGHEIENSPGETQVISHVKENKLESLFSTNL-N-KYDSDLCEVNA--GMPKGNL
SEPN--QKRPENEKCLLSIEDEESQQSTLSNLENHSQHSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILTSCALLAEKDS-D--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSDRANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGSTKPVQSENSDSDG-NMVEKPSGRKSKEKISSYSKTSKVERNDVGKEVKEKPSMK
RKLPFTISPSRNEDRDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKETG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPAAQKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 289)

DDDTPLHDSASSGHRDIVKLLLRHGGNAFQANKHGERPV
DVAETEELELLLKREVPLSDEDESYTDSEEAPSVNP-SSVDENIDSEAEKDSLVNENKQL
IPSKTSLP--SALDEYEFKDDDD----EEINKMIDDRHILRKELRKENEPEVEKNNLFVK
QEK-A-YPKPFKSKKQKPSRVL-YSSSESSDEEILQDKKVISTPCSVPETSTSDLRSKKE
YLVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRVTNLVGNPGLDSLDKTREEE
NFRKSFTPKDDASLHLFHMTTSKSPKNPCGLSEKQSTLLKQENAKTCLSP-GSSEMSLQS
DLIRHENNADSEFLLETSSGKYCKHKEKSKHHQKDFHLEFGEKSIPKIKDEDHSLTFDNS
EYTLKKTDKEGKTLKKHKLKHKDREKEKYKKEPDVEKEKYKNKDGNKAVQRSIEFDREFW
KENFFKSDETEDIFLNVEHEFLPSEKKSKL---EKTT-KDDKSSKEKHIPKERSFREERE
--KGKKENEKSFKEEKIKDLKEERE-SIPIDKE--TELLPLSISVKEESMGLHLTEKETE
IDKQEKNMKENKDRPEKRLQIKEKDLERSDRKNTEKEKKMKLDHKPEKDKLDLNECVEKT
KEKDRLNLQQAEK-YKESEKIKNITTVKKADDREKSRDKMDKKHDKEKTEKERHLGESKE
KHFIEKKGKLSDKDSEYIKLEKGKTKEKEREGEKREKCRDKESL--ASSKHVQEERRSTS
TEG-SKTLHEKLSSLKEKAKDEPLKTPDGKEKDKKD--KDIDRYKERDKHRDKTQLNNLP
KHK---SEVDKPKPKP----SMNPKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRSCLELNKVKDKEKTKNMLAESKNKELIRSKSSELSDVYTKEKH
LKDATSNRSQSVDIKNITNVGKSSSIT-DNNL--SRSPRSESEKTGLSSRSVSMISVASS
EDSCHTTMTTPRPIVEYDSDFILEGSDSQMSFSQSPFLTVAKSPAFHEREMDSLAELPER
IKLPYANRLPASHLRSS-SVEDVKLIINECRPIVEVRRCSIPPIIS-DHAKQFQ-TTSEE
NNQ-SL--LAVPSHI-CSSPKHEVSSCNVPEKDLSK-VSNLHSS-FDTSPVGSFNSKHSS
-SDTNVIKSTV-----GENPMHVEPCNLSNMAQQNKSWEIPVERLELLSTNDVHCSSYKV
PNQ-EPVIQGLCN--PDNRLLKEQNTSELLPQYQTEIHGNSGAHDSASF-MPSQPPGSFH
V-QSFPDA-ECIPKHMSLSYINNQESTLQQKT------QLQPNPILDTDNNFKKDLENTF
FPTDCQKTDAFVTVYAERTIQDTSPNYERTNALPIVSSEKDFLGNDACSQINTHAYSFSK
LIHKTSHNHEVDS-TADTQVISHEKE-KLESLVVINL-ADKSDLDLSEINA--GITKENL
NEQDGSKNNNENRRGFLPTEDEESQQSTLSNPEGHSQPSGQAEIHKCTQLVKVEVEETAE
DDKT-DLQIPQRITRNRANIMASQSKQIPITCVPLTEKDN-E-STSPRGRIRLTEEDDAQ
VHHPRKRKMSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQADDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRNDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-CSEKEGPEKKKTKKEAG-T
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTP-A-QKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
VPSKAPLP--SALDEYEFKDDDE----EEINKMIDDRHILRKELRKENESEVEKSSLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSSESSDEEILQNKKCSAPCS-VPETSNSDIQTKKE
YGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTALDCSDKTRDEG
NFRKSFSPKDDTSLHLFHISSGKSPKHSCGLSEKQSTPLKQEHSKTCLSP-GSSEMSLQP
DLVRYDN-IESEFLPESSSVKSCKHKEKNK-HHKDFHLEFGEKSNAKIKDDDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKSRDGTKELQRSVEFDREFW
KENFFKSDETEDLFLSMEHESLTLEKKSKL---EKNI-KDDKSTKEKHISKERNFKEERE
--KIKKESEKSFREEKIKDLKDERE-NVLTDKE--TEFSSLGVSATEDTIGLHSGEKEIE
IE---KHMKESKEKSEKRFQTKDRDIERADRKNSEKEKKIKHEHKSEKDRLDPSDSVDRI
KEKDKLYSHHTEKCHREGEKLKNITTIKKNDDRDKSREKMDRKHDKEKPEKERHPAESKE
KHLMEKKNKPSD-NSDYSKSEKSKN--KDREVDKKDKSRD--SVNISNSKHFQEERKSSI
TDS-NKAQHEKTFSLKEKTKDEPLRTPDGKEKDK----KDIDRYKERDKHKDKIQLSSSL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHALAESKNKELTRSKSSELTDTYTKEKH
CKDAVSNRSQSVDTKNTMSLGKSSFVS-DNSL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCLTTMTTPRPPVEYDSDFMLEGSDSQMSFSQSPFLPVAKSPALHDRELDSLTDLSER
IKASYASRLLTSHLRAS-SVEDAKLVTNEGRSAAEARRCSMPSVIC-EHTKQFQ-TISEE
SSQDG---SAVPRDI-SPSPKSEVS-SNVPERELLS-VSNIHSS-FAASPTRSINSKYNS
-ADTNVIKGAAPMGMLMGSPVHLEPSNQVGV-IQSKSWEM-----ESLNTGDFSCPNSAA
PDQ-DSSVQGFCN--PENKVLREQNID-FVSVHQTELPGNTCAQDPASF-LPSQQPCSSH
G-QSLSDA-ESISRHTSLSYVTTQEPGILQQK----NAIQMISSVLDTDTEPTKDMENTF
VLTDVQKTDAFVPVYSESTVEEAAPNFEKASTLPVLTSEKDFNGSDGSSQPN-PHYAFSK
LMFKSSSGHEAEKSTSDAQDTSHEKENKLESLGLTHL-NDKCDSDLCEMNA--GVPKGNL
SEPDNPKHCPESEKCLLSIEDEESQQSTLSSLENHPQPLAPPEMHKYGHLVKVELEESAE
DDKP-ENQIPQRMTRNKGNTGASQSKQLLASCALLPDKDS-E-SASPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKFGSTKAVQIENSDSDS-IMVEKPTGRKSKDKIASYSKTPKVDRNDVGKEMKEKSSMK
RKLPFTISPSRNEDRNSDTDSDPGHTHENWGERLIPSYRT-YSEKEGPEKKKVKKEAG-S
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSNLHHPLQTTPT-QKKTP
NSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKKEVPISDDEDSCSDSEETPSVNP-SSVDGNVDSEAEKESLVNDSKQV
VPTKAPLS--SALDEYEFKDDED----DEI-KMIEDRRILRKDLKKEDESEIEKNNIFVK
QEK-VVFPKSFKSKKQKPSRVL-YSSSESSDEEILQDKKIVSPPCSITETPNSDIKMKKE
F-VSNDHKQKGKVKRKLKNQSKNKENQELKQEKENT---RLTNVV-SSGLDSLDKAREEE
TFRKSFSPKEDSSLPFFHITASKSPKHPCGLSEKQSTPLKQENTKTCLSP-GGSEISLQS
EVVKYDHNTDSDYLMESSSGKSCKHKEKSKH-HKDFHLEFGEKSSPKMKEDENSSAFENS
ECMLKKIDKEGKTLKKHKLKHKEREKDKHKKEQDGEKEKHKHKDSAKEVQRNIEFDREFW
KENFFKSDEPEDILLNIDHESLSSEKKTKL---ERTIVKEDKSVKEKHIQKERSFKDERE
REKNRKENEKLCKDEKVKDTKEEKE-NMFADKE--TELFCSGVGFKDEPANMNLVEKEAD
TEKQEKNIKENKEKAEKRISVKEKDIEKVERKNVDKEKKIKHDK-PEKEKAELNEGIEKA
KEKTN--SQQVDKCHKENDKLKNCIAIKKLDDKERSKEKVDKKHDKEKIDKDRHVPESKE
KYCIEKKFKLSEKESEISKTEKGKNKDKEKEVEKKEKARDKDSLTVANAKHVQEEKK-CN
ITEGSKALHEKFLSLKEKPKDELLKTPDGREKDKKD--KDIDRYKERDKYKDKMQQNNCS
KLK---LESEKLKPKP----PLAPKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRSCLELNKIKDKEKTKHSLTESKNKELIRSKSSELSDIYMKEKQ
LKDATTSRSQSVDTKNFTNAGKS-SLV-LDNL--NRSPKSESEKTGLSSRSVSMISVASS
EDSCHTTVTTPRPIIEYDSDFMLEGSDSQMSFSQSPFLA--KSPALLERETDSIAELPER
IKPPFANRLPPAYIRSA-SVEDVKVVLNDCRPVVEVRRCSMPTVIS-EHTKQTR-TSEE-
--NSVL--LAVPNHI-CTSPKPEIAYCSLPERNFQNSMLGLHSN-FTSSPTKTGSSKHVT
-LDTN-IKNTTQLSPSEEIHMHLEPCSQSGLNQVTKPWDVPSDKLNSISNGFNCSGYGVP
EQD-TGTVVALHD--SENRTLKEQKLSEFLPQH-TELVENPSFQESASF-LPSQSPCSLH
I-QPLPNI-ECMSKHVSLPGTGNQEPIFVQQQQ---TVLQTTNSVLDTDTNSTREAENTS
SPPNIKKASVLITVYPETISKDISENFGGSNALSTLLPEKDFTANDACSQLNTNSYAFNK
IVYKNSQADEVDDSTANTQETQNKK-AQLENLVSTRVDNSKADNDLCEINV--GITKEII
NESSSKNYCTVDDRENMST-HDPPQY-PLSNLEDNSQQTPQELVLKYRPLVKLEVEETVE
DHKTEQQEIPQRITRNRANMLASQCKQSPIGCAHTSEKDS-ESSASIKGRIRLIEEDDAQ
VHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLEEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDCQTDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPQPGFPKPVQSENSDSDS-SMVEKPCGRKSKDKIASYSKTPKIDRSDVGKDMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAGGS
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSTRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVQELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GCYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDDSYTDSEEPHSVNP-SSVDENIDSETEKDSFSCDSKQI
NPSKAPLP--SALDEYEFKDDDD----EVVNKMIDDRHILRKELRKENDSEVEKNNLFAK
NEK-TFYAKSLKSKKQKLSRVL-YSSSESSDEDILQSKKVSSAPSSVPETSSCDVQTKKE
YGLSNENKQKGKVKRKLKNQDKNKENQELKQEKEGKENTRVMGLTVNATLESPEKTREEG
NFRKSFSPKDDTSLHLFHISTSRSPKHSCGLSEKQSTPLKLEHTKTSLSP-GSSEMSLQP
DLVRYEN-TESEFLPESSSVKSXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX-XXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXDKE--TEFSSFSTNASEECVGLHSVEKEAE
IE---KHVKESKEKPEKRFQSKEKDFDKTERKNSEKEKKIKHDYKSEKDKFDLSECVDRL
KEKDRLYSHHTEKCHKEGDKIKSN--TKKTDDRDKSREKMDRKHDKERPEKEKHLVERK-
--------KIPD-NSDYPKSEKNKNKEKDREVDKKEKSREKESVSTTNSRHFQEEKKSSV
TDGS--KAHDRTLSLKDKAKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKAQLNSLL
KLK---SETEKPKPK-----SPASKDSRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRSCAEGKVKEKEK-TKYVPAESKTKELTRSKSSELTDVLTKEKQ
PKDAASSRSQSVDAK-TMNLGKSPFAS-DNCL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCHTAVTTPRPPVEYDSDFMLEGSDSQMSFAQSPFLSSAKSPALHERELDNLGDLPER
IRPPYTSRLPASHLRSS-SVEDVKLIINEGRPPVEIRRCSLPSVIC-EHTKQSQ-AIAEA
SSQGG---PAVPKDT-CPSPKPDVA-FTVPEREHSN-ASNMNSS-FAASPTRSANSKSVS
-VDINAFKSA-AAGTSVDSSEHLESRNQVGV-IQNKAWEVPVDRLESLSTGDFICPNSGT
HDQ-DSSVQGLCN--TENKLVKEHSTN-FLSLPPTELSGNPCAQDPTSF-LPSQQPCSFH
S-QSLSEA-ESVSKQTSLSYVANQEPGSVQQK----STVRVISSAFDTDHDSTKDTENTF
LLADAQKTDAFVPVYSESAVQETSPTFEKL---TLLPSEKNFSGSDAPPQLNNAHYTFSK
LMSKSPSDQEVENSTSEISVISHEKD-KLENLSLTHL-DDKCDSDLCEMNS--GMPRGNL
PEQDNLKHCPESEKCLLSIEDEESQQSSLSSLDNHPQQ---SEMHKCGQSVKVELEENPD
DDKN-ENHIPQRMTRNKTNATANQSKQMIAGCALLPEKDH-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKERTQQSLAAVVDALKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLL-NVIPQAPPYYD-YVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLK-------------------
------------------------------------------

MPKSGFTKPVQSENSDSDS-SMVERPYGRKSKDKIASYSKTSKIDRGDMGKEMREKPSMK
RKLPFTVSPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-T
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAQSVNP-SSVDENIDSETEKDSFICGSK-I
LPNKAALP--SALDEYEFKDDDE----EEISKMIDDRHILRKEQRRENESEAERSGLFAK
QEK-TFYSKSFKTKKQKPSRVL-YSSTESSDEEALQNRKGSTACS-VAEASHSDMQAKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRLANLTVNTGLDCSEKYREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQ-TPLKQEHTKACISP-GSSEMSSQP
DLTRYDT-AEP----ESSNVKSYKHKEKNK-HQKDFHIEFGEKSNAKIKDEDHNPAFENS
DCTLKKMDKEGKTLKKHKLKHKEKDKEKHKKEVEGEKEKYKNKDNAKELQRSIEFDREFW
KENFFKSDETEDLFLTMEHESLI-EKKSKM---EKTM-KDDRSAKEKHVSKEKNFKEERE
--KAKKENEKSLREEKLKDPKEEKD-SASAEKE--AECCSVAVSAGQEAAGLHSSEKEMD
AEKQERHTKE-REKSDRRFQTKEKELDRNERKFSEKEKKIKHEHKSEKEKLDFSDGTDRV
REKDKLYSHQTERCHKDSEKLKNT--VRKTDDRERNREKADRKHDREKPERERYLAESKE
KHLEKRK--QSD-SNEYSKSEKVRTKDRDREGEKKEKLRDKESVNVTNLKHLQEERKSST
GDSSGKTQHEKALSLKERARDEPLKTPDGKEKDK----KDIDRYKERDKRKEKAQLNTLI
RLK---SETEKLKPKL----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRTCLELKVKDKEK-TKHAPTESKNKELTRSRSSELTDVYNKEKQ
SKDVGSNRSQSVDNKNVLNLGKPSYIL-ESSS--NRSPRSEGEKLGLSSRSVSMLSVASS
EDSCHT-VTTPRPLVEYDSDFMLEGSESQLSFSQSPFLSNAKSPALYERELEGLTELPER
LKPPYTNRLPVCHLRSS-SVEDVKLITNEVRPAVEIRRCSMPSVIC-EPIKHFQ-VSE-E
SSQ-GN--LAVPREN-CPSPKPEMS-SAVPERGLSH-VSDLHPN-STGSPTRSANSSYIS
-SDVNVIKSATLVGTLIDSSMHLEPSNQVGV-IPSKSWETPVDKLESLSTNDFICPDSNT
SDQ-DSSAQSFYN--SENKMLREQNTD-CLPLHQPELPGNSCAQDPASF-LSSPQPCSFS
N-QPLAGA-DSVPKPVSLSYVASQELGVLQQR----SASQMASSVLDSDNNFTEDVENTF
VLADIQKTNSFLPTYSESTVQEALPSFEKANTLLVLPSEKDFNGSDTA-QPN-THYAFSK
LTYKSSSSQEIEKGPDDTQIISHEKENKLQSLVLTQL-S-KCDSDLYEINA--GMPKANL
NEQENPKHGPDSEKYSLSTEDEESQQSTLSSVENHSQQSAQPEMHKYDQLSKVEVEENAE
DDKT-ENQTPQRMTRNKASTVVNPSKPMLAGCTLVAEKDN-E--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQRSLAAIVDSLKLDEIEPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPIQSENSD----------------NKIASYSKTQKIDRSDVSREMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSGNSGAPVYSKKMKEE---
----TLGITYSLMFLKLKQKSKDRNQNKARQNISLTFLFLTDSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTGLFQIICIPLLLP---HLKEC-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKIATSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKQSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LGMSAIEESMGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKESEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLTESKE
KHLMEKKNKPSD-NSEYTKSEKGKNKEKDRELDKKEKSRDKESVNITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
RLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSVAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSG-FAISPTGASNSKYVS
-ADRNVIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNSCAQDPTSF-MPSQQPCSFP
S-QSLSDA-ESISKHMPLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGNDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPIQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEK-SMK
RKLPFSISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICENKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENESEAEKNSLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEVLQNKKISTSCS-APETSNSDIQTKKE
YVVSSEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVANLAVNTALDCPEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEISLQP
DLVRFDN-TESELLPESSSVKYCKHKEKNK-HQKDFHLEFGEKSNAKVKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDGAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESVTLEKKSKL---EKNM-KDDKSTKEKHIPRERNCK-ERE
--KIKKESEKSYREEKIKDLKEERE-NVPTEKE--TEFSSLSISANDESIGLQSAEKEID
IEKQEKHIKESKEKSEKRFQTKEKDVEKTERKNSEKEKKTKHEHKSEKDKLDLSECVDRI
KEKDKLYSHHTEKCHKEGEKIKNIT-IKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-NSEYNKSEKGKSKEKDREIDKKEKSRDKESINITNSKHTQEEKKSSI
VDS-NKAQHEKPLSLKEKAKDEPLKIPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KVK---SEADKLKPKS----SPALKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHALAEPKNKELTRSKSSELTDAYTKEKQ
PKDAVSSRSQSVDTKNIMNLGKSSFVS-DNSL--NRSPRSETEKLGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSESQMSFSQSPFLPIAKSPALHERELDSLADLPER
IKPPYANRLPTSHLRSS-SVEDVKLVINEGRPIVEIRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LAVPRDT-CSSPKPEIF-SNVPERDHSN-VSSIHSS-FATSPTRSVSNKYVS
-ADINVIKSTVAVGTVVDCPVHLESSNQVGV-IQNKSWEIPVDRLETLNTRDLICPNSNA
PDQ-DSSVQGFCN--PENKILKE-NTD-FLSLHQTDLPGNCCGQDPASF-LPSQQPCSFP
S-QSLTDA-ESISKHTSLSYVANQEPGISQHK----NATQIISSVLDTDNESTKDTEDTF
VLPEVQKTDAFVPVYSESTIQEVSPNFEKTNTL---PSEKDFNGTDASTQLN-THYAFSK
LTYKSSSGHEVENSTADIQVISHEKE-KLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQDNSKHCSESEKCLLSIEDEESQQSTVSSLENNSQQSVQPEMHKYSQLVKVELEENNE
DDKT-ENQIPQRMTRNKASTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKG--SEFTSLGMSAIEESIGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYLHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-NSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDS-NKAQHEKPLSFKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSEVTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSTRSVSMISIASP
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKP-VF-SNVPERDLSN-VSNIHSS-FTSP-TG-ANSKYVS
-ADNL-IKNT-PVST----------------------------MDSVLESSQFICP-SNI
PDQ-ESSLQSICN--SENKILKE-NAD-FLSLHQTELPGNSCAQDPASF-MPSQQPCSFP
N-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQIISSALDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKENKLESLVLTHL-N-RCDSDICEMNA--GMPKGNL
NEQD-PKLCPESEKCLLSIEDEESQQSILSSLENHSQQSTQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKFGSTKTVQVENSDSNS-TMVEKTTARKSKDKIASYSKTPKVDRSDVGKEMKEKSSMK
RKLPFTISPSRNEDRNSDTVTNTNANAVRWFYFLSLEMFL-FLEKEGPEKKKMKKDAG-N
KKSAPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTLNHSVQTTPT-QKKTP
TSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELIRLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRNIVKLLLRHGGNPFQANKHGERPV
DVAETEELEMLLKREVPISDDEDSCSDSEEAPSVNP-SSVDGNVDSEAEKDSVANNSKQT
VPSKAPLP--SALDEYEFKDDDE----DEMKKMIDDKHILRKDPRKEDETEVEKTSLFVK
QEK-VVFSKSLKNKKQKPSRVL-YSSSESSDEEIIQDKKMVS-PCSVSETSNSDVRVKKE
YMVTNEHKQKGKVKRKVKNQSKNKENQEVKQEKENA---RVTNIA-TSGLDPLDKAREEE
TFKKSFTSKEDSSLHLFHITAGKSPKHPCGLSEKQSTPLKQENTKTCLSP-GGSEITLPS
ELVRYDHNTDSDYLVESSSGKSCKHKEKSKHHQKDFHLEFGEKSSPKIKEEDNSSTFESS
EYTLRKIDKEGKTLKKHKLKHKEREKEKHKKEQDGEREKHKHKDNVKDVQRSIEFDREFW
KENFFKSDENDDTLINTEHESLSSDRKSKL---EKTVVKEDKLVKERQFQKERSIKDERE
KEKNKKENEKFLKDEKIKDTKEEKE-VMLADKE--IELFCFG--VRDEAASVHIVERETD
TEKQEKNLKENREKTEKRFSIKEKDFEKIERKHGEKEKKLKHEYKIEKDKAEVNENTEKV
KEKSS--FQQAERCHKENDKIKSMGALKKVDDKERNKEKTDKKHDKEKADKERHWAESKE
KHCTERKVKQSEKESEYTKSEKNRTREK--ELEKKDKSKDKETSSLASSKHMQEERR-CT
ITESNKTVHDKLSSLKEKPKDDLLKTPDGREKDKKD--KDIDRYKERDKHKDKLHQSSLL
KLK---LEHEKLKPKP----APALKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRTCSEHN--KMKEKPRHSLAEVKGKELIRSKSSELPDVCIKEKQ
QKDATSNRSQSVDTRSVNVVKT--SLA-LDNL--NRSPKSESEKMGLSSRSVSMVSVASS
EDSCHTTVTTPRPVTEYDSDFMPEGSDSQMSFSQSPFLASAKSPALVEKEADGLAELPDR
IKPPFTNRLPQMYVRSA-SAEDVKLVLNECRPVIEVRRCSMPAAVS-EQSKQPR--TSEE
LNQNAL--PSVQNYS-SASPKPEL-LCSALERDFQS-VAVLQSS-FTSSPNRAVSNKQAT
-TGTNTIKDNAQMSPSEDSSMHLEPCSQSGVTQQTKLWDVPFERLNSLNNDFNSSGCGMS
EQD-AKSIIAVHN--SESRTLKEQRVSEFLPQH-PEIKGSSSSQESASF-LPSQSPCSLP
I-QPLP----VVSKNVSLPGIISQDSSFVQQQ----NLVQTATSALETDATSTRELENAF
FPSNIRKTDAPMAVYSESSAKDVSQGYEKVNDLPMVPSEKDTPESDSSSQLNVNLYSFSK
VVCKNALGE-VDSNTADTSDIRNEKDQQ-EKLVSVHVVDSKANAELCELSS--GMSKGIT
NELVNKSPCTADRENVLA--DDSPQYSSISNLENSSQQITQEEAHKYSQIVKVE-EV-AE
DQKMEQQEVPQRITRNRANLLANQGKQNPLGCTQTSEKES-ESSASMKARIRLTEDDDAQ
VHHPRKRKVSRVPQPVQANPSLLQAKEKTQQSLAAIVDSLKLEEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFKQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDAQTDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTQKIDRSDAGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKESLICESKQI
VPSKAPLA--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENESEPEK-SLFAK
QEK-AFYSKSFKSKKQKPSRVL-YSSTESSDEEVVQSKKISAASS-VPETSNSDTQTKKE
YE----YKQKGKVKRKLKNQSKNKENQELKQEKEEKENTRVTNLTVNAALDCSEKTREEG
NFRKSFSPKDDSSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPEGSSVKSYKHKEKNK-HQKDFHLEFGEKSNAKIKDEDHNPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKETEGEKEKYKNKDGVKELQRSMEFDREFW
KENFFKSDETEDLFLNMEHESLT-EKKSKL---EKSI-KDEKSTKEKHVSKERNFKEERE
--KIKKENEKSFREEKIKDAKEERE-NVPTDKE--IEFTSLGISINEESVGLHSMEKEID
VEKQEKHIKESKEKSEKRFQTK--DVEKTERKNSEKEKKIKHEHKSEKDKLDFSECVDRI
KEKDKLYSHHPEKCHKEGEKIKNA--TKKTDDREKSREKVERKHDKEKPEKERHLTESKE
KHLIEKKSKQSD-NTEYTKSEKGRNKERDRELDKKEKSRDKEG--ITNSKHVQEEKRSSM
MDS-CSKAHEKTSSLKDKTKDEPLKTPDGKEKDKKD--RDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHGLAELKNKELTRSKSSELTDTYTKEKQ
SKDAVSSRSQSVDTKTVTSLGKSSFVS-DSSL--NRSPRSEGEKPGLSSRSISMISVASS
EDSCLTTMTTPRPLAEYDSDFMLEGSESQMSFSQSPFLPIAKSPALHERELDSLAELPER
IKLTYANRLPATHLRAS-SVEDVKLIINEGRPTVELRRCSMPSVIC-EHIKQFQ-TTSEE
SNQGS---LAVPRDN-CPSSKSEVS-SNVPERDLSN-VSNIHCS-FTASPASSANSKYIS
-DDVNVIKSTGPVATLMDSPVHLDPSSQVGV-TQSKSWEIPVDRIESLSTSDFICPNSGT
PDQ-DFSVQGFCN--PENKILKEQNTE-YLSQPQTELPGNSCAQDPVSL-LSSQQPCSFP
S-QSLSDTSDTVTKHVSLSYVATQELGILQQK----DAVQMISSVSDIDNDSTKDVENTF
VLADVQKTDNFVPVYSESTIQEGSSNFEKASMLPVFPSEKDFTGSDGHSPLN-TH-AFSK
LTYKSSSSYEFENSTTDTQVILHEKENKLECLFSTHL-N-KYDPDLCEMNT--GMPKGNL
NEQDNPK-CPESEKGLLSIEDEESQQSTLSSLENHSQHSAQPEMNKYGQLVKVELEENAE
DDKT-ENQIPQRMTRTKANTMANQSKQILASCALLSEKDS-D--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDNKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPIQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKTPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFTSLGMSAIEESIGLHLVEKEID
IEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-NSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQINSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSEVTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTIEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPGDT-SPSPKPEVF-SNVPERDLSN-VSNIHSS-FATSPTGASNSKYVS
-ADRNLIKNTAPVNTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKVLKE-NAD-FLSLRQTELPGNSCAQDPASF-MPPQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQIISSALDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDTQVISHEKENKLESLVLTHL-S-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSTQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRNDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-CSEKEGPEKKKTKKEAG-T
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQ-TPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTGLFHMCQVLRAQRLCQNICQC--TASFIREENAL
TRGVCPMSSECACDVADFL-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

MPKSGFTKPVQSENSDSDS-NMVEKPCGRKSKDKIASYSKTPKIDRS-VGKEIKEKSSMK
RKL-FTISSSRNEEQDSDTDSDPGQTSENWGERLMSSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPT-QKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKDFAXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX--XXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXKLKHKEKEKEKHRKETEGEKEKYKNKDGAKELQRNVEFDREFW
KENFFKSDETEDLFLNMENETLTFEKKLKL---EKTM-KDDRSAKEKYTSKERNFKEERE
--KIKKESEKSFREEKIRDSREERE-NVSTDRE--TESSSLGISAKEESVGLRSVEKEID
IEN---YMKESKEKSEKRCQTKEKDIEKTDRKSSEKDKKMKYDYKLEKDKLDISECGDRV
KEKEKLYSHHIEKCHKDGEKIKNITTIKKIDDRDKSREKMDRKYDKEKPEKEKHPAESKE
KHLIEKKNKQSD-NSEYIKSEKGKTKEKDKEVDRREKSRDKESINVTNSKHLQEEKK-SS
IGDGCKAQNEKSVSLKEKMKDEPLKTPEGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SETDRPKPKL----LPVSKDSRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELK-VKDKEKIKHVLPESKNKELTKSKSSELTDSFTKEKQ
SRDIISSRSQSLDTKNIINLGRSSFVS-DTSI--NRPPRSEGEKPGLSSRCLSMISVASS
EDSCHATVTTTRLPVEYDSDLMMEGSDSQMSFSQSLFLPIVKSPALHERESDSLAELPER
IKPTYANRLPTSHLRSS-SIEDVQLITNESRPFVEVQRCSIPSVTC-EDAKQFQ-TVPEE
SNQGTF--LVVPGNT-CPSPKAEV-FSNVPEKDVSS-MSNIHSS-FSVSQARSINNKYIS
-ADTNVIKNTVPISTLVESPIHLEPSNQVGVIH-NKSWEIPLDRLESLSTSDFTCLNSGK
PDQ-DSSGQDVCN--SENKLLKEDTDFSSLHXX-XXXXXXXXXXXXXXX-XXXXXXXXXX
X-XXXXXX--XXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX--XXXXXXX
XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX-XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSVSIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSRTPKIDRSDVGKEVKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-FSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSIICESKQI
IPKA---PLSTALDEYEFKDDDD----EEINKMIDDRHILRKELRKENESEVEKNSLFAK
QDK-AFYPKSFKNKKQKPSRVL-YSSSESSDEEILPNKKVSTPCS-VPETSNSDTQTKKE
YGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTIA-TVDCSEKTREEG
NFRKSFSPKDDTSLHLFHISSGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKNK-HQKDFHLEFGEKSNAKIKDEDHSSTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDGVKELQRSVEFDREFW
KENFFKSDETEDIFLSIEHDPLT-EKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERE
--KIKKESEKSCKEEKIKDLKEERE-NIPIGKE--TEFSSLGISASEESIRLHSMEKEIE
IEKQEKHIKESKEKSDKRFQSKEKDIEKAERRNSEKEKKIKHEHKSDKDKLDLSECVDRI
KDRDKLYSHHTEKCHKEGEKIKNIT-IKKPDDREKSREKTDRRHDKDKPEKERHLAESKE
KHMMEKKSKQSD-NSDYTKSEKSKN--KDREVDKKEKSRDKESVNISNSKHFQEEKRSSI
ADSSKAQ--QEKTSLKEKTKDEPFKT-DGKEKDKKD--KDIDRYKERDKHKDKIQLNSLF
KLK---SEADKPKPKL----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLKNRNCLELKVKDKEK-TKHTLAESKNKALTRSKSSELTEPYTKEKQ
SKDAVSNRSQSVDTKNIMNLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFLLEGSDSQMSFSQSPFLPIAKSPALHEKDFDSLAELPER
IKPPYTSRLPTSHLRSS-SVEDVKLVINEGRATVEVRRCSMPSVIC-EHTKQFQ-TTSEE
SNQGG---LAVPRDI-CPSPKSEVS-SNVPERELSN-VSNINSS-FATSPTRSINSKYIS
-ADINVIKSSTPVGTSMDSPVHLEPSNQVGV-IQNKSWEIHVDRLDSLSTSDFIGPNSST
SGQ-DSSVQVFCN--SENKILKEQNTD-FLCLHQTELPVNSCAQDAASF-LPSQQPGSFH
S-QSLSDT-ESISKHMSSSYAANQDPGILQQK----NAVQIISTVLDTDNESTKDMENTF
ALTDVQKTDTFVPVYSENSVQEASPNFEKANTLPILPLEKDFNGSDSSSQLN-IHYAFSK
HIYKSSNSHEVENSTSDIQVISHEKESKMESLVLTHL-NDKCDSDLCEINA--GMPKGNL
NEQDNPKLCLESEKCLLSIEEEESQQSTLSCLENHSQQPAQPEMHKYGQLIKVELEENAE
DDKT-ENQIPQRMTRNKANTVANQSKQILASCAILPEKDS-E-SSSPRGRIRLTEEDDPQ
VHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKSSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LGMSAIEESMGLHLVEREID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKESEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLTESKE
KHLMEKKNKQSD-NSEYTKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSFFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSG-FAISPTGASNSKYVS
-ADRNVIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNSCAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGNDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISREKENKLESLVLTHL-N-RCDSDLCEMNT--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLMSSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEARSVNP-SSVDENIDSETEKDSLICESKQI
VPSKAALP--CALDEYEFKDDEE----EAVNKMIDGRRILRKELRRENETQVEKSSLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSSESSDEEILQNKKCSAPCS-VPETSNSDVQTRKE
YGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTALDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHSKTCLSP-GSSEMSLQP
DLVRYDN-IESEFLPESSSVKSCKHKEKNK-HQKDFHLEFGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDGAKELQRSVEFDREFW
KENFFKSDETEDLFLSMEHESLTLEKKSKL---EKNI-KDDKSTKEKHVSKERNFKEERE
--KIKKESEKSFREEKIRDLKDERE-NVPTDKE--TEFSSLGISASEESIGLHSVEKEIE
IEKQEKHMKESKEKSEKRFQSKEKDVEKAERKNSEKEKKVKHEHKSEKDRLDPSECVDRI
KEKDKLYSHHTEKCHKEGEKIKNITTVKKTDDREKSREKIDRKHDKEKLEKERHPAESKE
KLD---GKKQSD-NTEYNKSEKSKNKEKDRERKEK--SR--DNVNITNSKXXXXXXXXXX
XXX-X------------------------------------------------------X
X-----------------------XXXXXXXXXXXXXXXXXXXXXXXLSLKDLEIEQWHR
KHNEKIKQKEKERLRNRNCLELKVKDKEK-TKHAPAESKNKELTRSKSSELTDAYTKEKR
CKDAVSNRSQSVDTKNTVNLGKSSFVS-DNSL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCHTTVTTPRLPVEYDSDFMLEGSDSQMSFSQSPFLSIAKSPALHERESDSLTELPER
IKASYTSRLPTAHLRS--SVEDAKLVINEGRPTAEVRRCSMPSVIC-EHTKHFQ-TISEE
SGQDGL---VVPRDA-CPSPKPEVP-SDVPERELSS-ASNTHSS-FAASPTRSVNSKYTS
-ADTNGIKSTAAVGTLMDSPVYLEPSNQVGV-IQSKSWEIPVDRRESLSASDFICPNSTT
SDQ-DSSVQGFCN--SEHKILKEQNID-FVSLHQTELPGNTCAQDPASF-LPSQQPCSFH
S-QSLSDA-ESISKHRSLSYVANQEPGILQQK----NAIQIINSVLDTDNESTKDMENTF
ILTDVQKTDAFVPVFSESTVQETAPNFEKANTLPVLPSEKDVNGSDASSQPN-THYAFSK
LMYKSSSGHEAENSTSDIQVISHEKENKLESLVLTHL-NDKCDSDLCEMNA--GMPKGNL
NEQDNPKHCPESEKCLLSIEDEESQQSTLSSLENHSQQPGQPEMHRYGHLVKVELEESAE
DDKT-ENQIPQRMTRNKANTIANQSKQILATCTLLADKDT-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQASPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFAKPVQSENSDSDS-NMVEKSYGRKSKDKIASYSKTPKIDRSDVGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEARSVNP-SSVDENIDSETEKDSLICESKQI
VPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKELRKENESEVEKNSLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSSESSDEEILQNKKCSTPSS-VPETSNSDIQTKKE
YGISSEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTAVDCSEKAREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHCCGLSEKQSTPLKQEHSKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKDKNK-HQKDFHLEFGEKSNAKVKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNRDGAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKSI-KDDKSTKEKHVSKERNFKEERE
--KVKKESEKSFKEEKIKDLKDERE-NIPTDKE--TEFSSLGISASEESVGFHSVEKEIE
IE---KHIKESKEKFEKRFQTKEKDIEKAERKNSEKEKKIKHEHKSEKDRLDLSECIDRI
KEKDKLYSHHTEKCHKESEKVKNFTTIKKTDDRDKSREKMDRKHDKEKPEKERHLAESKE
KHSVEKKTKQSD-SGDFARSEKSKSKEKDREVDKKEKSR--DSVNITNSKHFQEERKSSI
ADS-NKAQHEKTLYLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSSL
KLK---LEVEKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRNCLELKVKDKEK-TKHSLAEFKNKELTRSKSSELTDAYTKEKQ
SKDAISNRSQSVDTKNPVSLGKSSFVS-ENSL--NRSPRSESEKLGLSSRSVSMISVASS
EDSCHTTVTTPRPPVEYDSDFMLEGSDSQMSFSQSPFLPVAKSPALHERELDSLAELPER
IKASYTSRLPASHIRSA-SVEDVKLVLSEGRPTVEVRRCSMPSAIC-EHTKQFQ-ATSEE
SNQDGL---ALPREV-CASPRPEAS-SNVPERELSS-ASNIHSS-FAASPAMSVNSKYTS
-ADINVIKSSAPVVTLVDSPIHLEPSNQVGV-IQNKAWEIPVDRLGPLSTSDFICSNSCT
PDQ-DSSVQGFCN--SENKILKEQNID-FLPLHQTELPGNTCAQDAASF-LPSQQPCSSH
S-QSLSDA-ESISKHMSLSYVTSQEPGILQQK----NAIQMINAVLDTDNESTKDRENTF
VLADVQKTDAFTPVYSESTVQEAAPNFEKANSLPVLPLEKDFNGSDASSQPN-THYALSK
LLYKSSSSHEVENSTSDIQVISHEKE-KLESVVLTHL-HVKCDSDLCEINA--GVPKGNL
HEQDNPKHCSESLKCLLSIEDEESQQSTLSSLENHSQPSAQPEMHKYGHLVKVELEESAE
DDKT-ENQIPQRMTRNKANTVANQSKQILASCPLLPDKDS-E-SSSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQGENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIDRSDPSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTAPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISMGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAQSVNP-SSVDENIDSETEKDS-LCESKQI
LPSKAPLP--SALDEYEFKDDDE----EEINKMIDDRHILRKEQRKENETEAEKSGLFAK
QEK-AFYSKSFKNKKQKPSRVL-YSSTESSDDEVLQNKKVSTSCS-VPETSNSDIQTKKE
YE----YKQRGKVKRKLKNQNKNKENQELKQEKEGKENTRITNSTVSTSLDCSEKTREEG
TFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHSKVCLSP-GSSEMSLQP
DLARYDN-TESEFLPESSNVKSYKHKEKSK--QKDFHLEFGEKSHTKIKDEEHSPAFENS
DCSLKKMDKEGKTFKKHKLKHKERDKEKHKKEAEGEKEKYR-KDGTKELQRSIEFDREFW
KENFFKTDETEDLFLNMEHESLTLEKKSKL---EKSM-RDDKSAKEKHVSKEKNFKEERE
--RFKRENDKSFREEKLRDVKEERE-SLSTDKE--TEFSSLAISLNQESIGLHSMEKEID
IEKQEKYLKE-REKSDKRFQTKEKEIDKTERKISEKEK-KKHEYKLEKEKLEFSECIDRI
KEKDKLYSHQSEKCHKENEKTKNT--IKKTDDREKNREKVDRKHDKEKPEKERCLAESKE
KHFVEKKNKQSE-NSEYTKSEKGRNKEKDREGDKKEKFRDKESINVTSSKQLQEEKRSNI
GDSSGKAQHEKTVSLKEKAKDEPLKTPDGKEKDK----KDIDRYKERDKRKDKIQLNTLL
KLK---PEADKPKPKS----SPAPKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRNCVELKIKDKEK-TKHTPAESKNKELTKSKSSDLADAYTKDKQ
SKDVGSSRSQSVDTKNTMNFGKSSFIS-DNSL--TRSPRSENEKPGLSSRSVSMISVASS
EDSCHTTVTTPRPLVEYDSDFMLEGSESQMSFSQSPFLSVAKSPALHERELESLAEMPER
LKPSYANKLPASHLRSS-SVEDVKLIISEVRPTVEIRRCSMPSVIC-EPTKQFQ-VS-EE
SNQGSL--LTVPRDI-CPSPKPEVS-SSVPERDLSN-MSNIHPS-FTSSPTRSVNSKYIS
-SDTNIIKSTAPTGTSLDSPVHLEAAHQVGV-IQSKSWEMPVDKLESLNTNDFICSNSVT
PDQ-DSNANNFCN--SENKVMREQNVD-CLSLHQTELPGNSCVQDPAAF-LPSQQPCSFP
S-QSLLDT-ESASNPMSLSYVANQEPGVLPQR----N-VNMISSALETDNNFTKDMENTF
VLADIQKTDTFVPVYTESTIQEALPNYEKANTMLVLPSEKDFSGSDASSQLN-AHYAFNK
LAYKSSSNHEVERSTTDTQVLLHEKENKLQSLVLTHL-S-KCDSDLYEMNA--GMPKGNL
SEQDNPKHGPESEKCSLSIEDEESQQSTLSSLENHPQQTVQPEMHKYDQLVKAELEENAD
DDKT-ESQVPQKMTRNKASTMANQNKQIPAGCTLLPEKDS-E--SSPRARIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKSYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPSHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDIQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTSKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNVKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LSMSAIEESMGLHLVEKEID
IEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKERKIKHEHKSEKDKLDLSECVDKI
KEKDKLYSHHTEKCHKEGEKSKNTVAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKE
KHLMEKKNKQSD-SSEYTKSEKIK-----------GKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDREK-TKHTPTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFVSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-MSNIHSG-FTISPTGASNSKYVS
-ADRNVIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNSCAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDTENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGNDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKENKLESLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMQKYGQLVKAELEENAE
DDKT-ENQIPQRMTRNKANTMANQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYNKTPKIDRNDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLLSSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQ-TPA-QKKTP
SSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELISLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAHSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----DEINKMIDDRHILRKEQRKENESEAEKNSLFAK
QEK-TFYPKSFKSKKQKPSRVL-YSSTESSDEEILQNKKVSTPCC-IPETSSSDIQTKKE
YVLSSEHKQKGKVKRKLKNQNKNKENQELKQDKEGKENTRVTNLTVNAALDCSEKAREEG
SFRKSFSPKDETSLHLFHISTGKSPKHSCGLSEKQSIPLKQEHIKTCLSP-GSSETSLQP
DLVRYDN-TEPELLPESSSVKSCKHKEKNK-HQKDFHIDLGEKSNAKIKDEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKETEGEKEKYKNKDGAREPQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLLLEKKSKS---EKNL-KDDKSSKEKHVSKERNFKEERE
--KVKKEIEKSFREEKVKDLKEERE-NVPADKE--TEFSSLGINTSEESVGLHPAEKEMD
IEKQEKHIKESKEKSERRFQTKEKDAEKTERKNSEKEKKIKHEHKSEKDKSDLCESVDRV
KEKDKLYSHHAEKCHKEGEKTKSIT-LKKSDDREKSREKMDRKHDREKSEKEKHLAENKE
KHLMEKK-KQSD-NCEYTKSEKGKSKDKDREADKKEKSRDKESVNISNSKHLQEEKKSSI
VDS-SKAQHDKTLSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKH--KIQLNSLF
KLK---PEVDKSKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKVKDKEK-AKHALAESKNKELTRSKSSEITDAYIKEKQ
SKDTVSSRSQSVDTKTTVNLGKSSFVS-DSSL--NRSPRSESEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPLVEYDSDFMLEGSESQMSFSQSPFLPVAKSPALHERELDSLAELPER
IKTPYASRLATSHLRSS-SVEDIKLIISEGRP-VEVRRCSMPSVIC-EHAKQFQ-NVSEE
SNQGSL--LAVPRDI-CPSPKLEVS-SNVPEKDLSH-MSHVHSS-FAASPTRSVNSKYIS
-ADTNVIKSTASVGTLMDSPVHSEPSNQVGV-IQNKSWEIPGDRLESLSTSDVICPNSSM
PDQ-DSSVQGFCN--SENKILKEQNAD-FLSLHQTELPGNSCAQDPA-F-LPSQQPCSLA
S-QPLSDA-ESISRHMSLSYVASQEPGILQQK----NVVQVISSVLETDNESLKDVENNF
VL-DVQKTDTFIPVYSESTVQEAAPNFEKANTLPVVPSEKDLNGSDAVSQLN-THYAFSK
LIYKSSSGHEGENITTDVQIISHERENKLESLVLTDL-N-KCDSELCELNE--GMPKGNL
SEQDHPKHCPEGEKCLLPIDDEESQQSTLSTMENHLQQSAQPEMHKYGQLVKVELEENAD
DDKA-ENQIPQRMTRNKANTIATQSKQILTSCTVLSEKDS-E-SSSLRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTQKIDRSDAGKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKESLICESKQI
VPSKAPLP--SALDEYEFKDDDE----EEINKMIDDRHILRKEQRKENESEAEK-SLFAK
QEK-VFYSKSFKSKKQKPSRVL-YSSTESSDDEVLQSKKISTASS-VPETSNSDTQAKKE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEEKENTRVANLTVNTALDCSEKTREEG
NFRKSFSPKDDSSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSYKHKEKNK-HQKDFHLEFGEKSNSKIKDEDHNPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDGPKELQRSVEFDREFW
KENFFKSDETEDLFLNMENESLTLEKKSKL---EKST-KDEKSSKEKHVSKERNFKEERE
--KIRKESEKSFREEKIKDAKEERE-NVPTDKE--IEFTSLGISVNEESVGLHSVEKEID
IEKQEKHIKESKEKSEKRFQTK--DTEKTERKNSEKEKKIKHEHKSEKDKLDFSECVDRI
KEKDKLYSHHPEKCHREGEKIKNS--IRKADDREKSREKVERKHDKEKPEKERHLIENKE
KHALEKKNKQSD-NTEYTKSEKSRSKEKDRELDKKEKSREKEG--ITNSRHVQEEKKSSM
TDSFSKAQHEKISSLKDKTKDEPLKTPDGKEK--KD--RDIDRYKERDKHKDKIQLNSLL
KLK---SETDKPKPKL----SLPSKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHGLAESKNKELTRSKSSELTDTYTKEKQ
SKDAVSSRSQSVDTKNVMSLGKSSFVS-DSSV--NRSPRSEGEKLGLSSRSISMISVASS
EDSCHTTVTTPRPLAEYDSDFMLEGSESQMSFSQSPFLPVAKSPALHEREMDSLAEPPER
IKPPYANRLPATHLRAS-SVEDVKLVMNEGRPTVEVRRCSMPPVIC-EHIKQFQ-TTSEE
SNQGS---LAVPKDN-CPSPKSEVS-SNVPERDLSN-VSNIHSS-FMTSPTRSANGKYLS
-DDVNVIKSTGPVGTLMNSPVHSEPSSQVGV-IQSKSWEIPVDRLESLSSSDFLCPNSST
PDQ-DFSVQGFCN--PENKILKEQNTE-YLSLHQTELPGNSSAQDPVSF-LSSQQPCSFP
T-QSLSDA-DSVSKHVSLSYVATPELGILQQR----DAVQMISSISDTDNESTKDVENTF
VLTDVQKTDTFIPGYSESTIQEASPNFEKASMWPVLPSEKDLNGSDGLSPLN-TH-AFSK
LTHKSSSSHEVENSAPDTQVMSHEKENKLECLFSSHL-N-KYDPDLCEMNA--GVPKGNP
HEQDNPK-CPENEKGLLSIEDEESQQSTLSSLENHSQHSAQPEMHKYSQFVKVDLEENAE
DDKT-ENQIPPRMTRNKANTTANQSKQILASCALLPEKDS-D--SSPRGRIRLTEEDDPQ
IHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

------------------------------SKDKIASYSKTPKIDGSDVGKEIKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSFRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPT-QKKAP
SSSSRQKDKVNKRNE

PF00023 // ENSGT00760000119090_6_Domain_0 (196, 228)

RGETPLHMAAIRGDVKQVKELISLGANVNVKD

ENSGT00760000119090_6_Linker_0_1 (228, 229)

F

PF00023 // ENSGT00760000119090_6_Domain_1 (229, 261)

AGWTPLHEACNV
GYYDVAKILIAAGADVNTQG

ENSGT00760000119090_6_Linker_1_2 (261, 262)

L

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 294)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSEIEKDSLICESKQI
IPNKAPLP--SALDEYEFKDDDD----EEVNKMIDDRHILRKELRKENESEIEKNNLFAK
QEK-AFYPKSFKSKKQKSSRVL-YSSSESSDEEVLQNKKVPT-PCSIPETSNSDIQTKKE
YVVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTALDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEVSLQS
DLVRYDN-TESEFLPEGSSVKSCKHKEKSK-HQKDLHLEFGEKSNAKIKEEDHSPTFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHRKETESEKEKYKNRDGAKELQRNVEFDREFW
KENFFKSDETEDLFLNMEHETLTFEKKLKL---EKNI-KDDRSTKEKHVSKERNVKEERE
--KIKKESEKSFREEKTKDLKEERE-TVSTDRE--TESSSLGISAKEEPIGLHSLEKEID
IEKQEKHTRESKEKSEKRFQTKEKDFEKTDRKNSEKEKKIKHDYKSEKDKLDVSECTDRG
KEKDRLYSHHTEKCHKEGEKVKNITTTKRTDDRERSREKIDRKHDKEKPEKERHPADSKE
KHLMEKKNKQSD-NNEYIKSEKGKSKEKDREVDKREKSRDKESINITNSKHLQEEKK-SS
VADSSKAQHEK-SSLKEKTKDEPLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQLNSLL
KLK---SETDKPKPKS----LPASKDSRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNSLELK-VKDKEKIKHALAEPKNKELTKSKSSELTDAYAKEKQ
SKDAVSNRSQSLDTKNVMSLGKSPFVS-DTSL--NRSPRSESEKPGLSSRSVSMISVASS
EDSCT-TMTTPRPPVEYDSDFMLEGSDSQMSFSQSPFLPIAKSPALHERELDSLAELPER
IKPTYANRLPTSHLRSS-SVEDVKLIINESRPVVEVRRCSIPSVIC-EHAKQFQ-TISEE
SNQGTL--LAVPRDI-CPSPKPEV-SSNVPEKDFSN-MSNIHSS-FAASPTRSVNSKYIS
-AETNVIKSTAPI----ESPVRLEPSNQVGVIQ-NKSWEMPVDRLESLSSSDFTCTNSSK
ADQ-DSSGQDFCN--SENKILKEQNTDFSSLHQ-TELPGNSCAQEPASF-MPSQPLCSYH
N-QLLSDA-ESTSKHMSLSYVANQEPDISQQK----NSVQMISSVLDADNESTKDMENNF
VPADIPKTDAFVSVYSENTIQEVSPAFEKANTLPVLPSEKDFNGSDASSQLSTH-HAFSK
LMCKSSSGLEVENSTTDTQVISHEKGNKLESFILT--HLNKCDSDFCEMNA--GMPKENL
NEQDNPKHCLESEKCLLSIEDEESEQGILSNLENHSQQSVLPEIHKYGQFIKVEIEE-NP
EDDKTENHTPQRMTRNRANTMANQSKQLLAGCTLLSEKDN-E-SSSLRGRLRLTEEDDPQ
VHHPRKRKVSRVPQPVQVSPFLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVMRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSITIYEIQEFYVPLVDVNDDFELTPI

MPKSGFTKPVQSENSDSDS-NMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-N
KKSTPVSILFGYPLSERKQ------MALLMQMTARDNSP--DSTPNHPSQTTPA-QKKTP
SSSSRQKDKV

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSDDDESYTDSEEAQSVNP-SSVDENIDSETEKDSLICESKQI
LPSKAPLP--SALDEYEFKDDDD----EEINKMIDDRHILRKEQRKENEPEAEKTHLFAK
QEK-AFYPKSFKSKKQKPSRVL-YSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKE
YVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSP-GSSEMSLQP
DLVRYDN-TESEFLPESSSVKSCKHKEKSK-HQKDFHLEFGEKSNAKIKDEDHSPAFENS
DCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKNKDSAKELQRSVEFDREFW
KENFFKSDETEDLFLNMEHESLTLEKKSKL---EKNI-KEDKSTKEKHVSKERNFKEERD
--KIKKESEKSFREEKIKDLKEERE-NIPTDKD--SEFT-LGMSAIEESMGLHLVEKEID
VEKQEKHIKESKEKPEKRSQTKEKDIEKMERKNFEKEKKIKHEHKSEKDKLDLSECADKI
KEKDRLYSHHTEKCHKESEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLTESKE
KHLMEKKNKQSD-NSEYTKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSI
VDG-NKAQHEKPLSLKEKTKDEPLKTPDGKEKDK----KDIDRYKERDKHKDKIQLNSLL
KLK---SEADKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRNCLELKIKDKEK-TKHTPTESKNKELTRSKSSELTDAYTKEKQ
PKDAVSNRSQSVDTKNVMTLGKSSFVS-DNSL--NRSPRSENEKPGLSSRSVSLISVASS
EDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPER
IKPPYANRLSTSHLRSS-SVEDVKLIISEGRPTVEVRRCSMPSVIC-EHTKQFQ-TISEE
SNQGSL--LTVPRDT-SPSPKPEVF-SNVPERDLSN-VSNIHSG-FAISPTGASNSKYVS
-ADRNVIKNTAPVGTVMDSPVHLEPSSQVGV-IQNKSWEMPVDRLETLSTRDFICPNSNI
PDQ-ESSLQSFCN--SENKILKE-NAD-FLSLPQTELPGNSCAQDPASF-MPSQQPCSFP
S-QSLSDA-ESISKHMSLSYVANQEPGILQQK----NAVQISSSVLDTDNESTKDAENTF
VLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGNDASTQLN-THYAFSK
LTYKSSSGHEVENSTTDIQVISHEKE-KLEGLVLTHL-N-RCDSDLCEMNA--GMPKGNL
NEQD-PKHCPESEKCLLSIEDEESQQSILSSLENHSQQSAQPEMHKYGQLVKVELEENAE
DDKT-ENQIPQRMTRNKANTIVNQSKQILASCTLLSEKDS-E-SSSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPKFGSTKTVQVENSDSSS-TMVEKTTARKSKDKIASYSKTPKVDRSDVGKEMKEKSSMK
RKLPFTISPSRNEDRNSDT------------------------EKEGPEKKKMKKDAG-N
KKSAPVSILFGYPLSERKQ------MALLMQMTARDNSP--DGTLNHSLQTPPT-QKKTP
TSSSRQKDKVNKRNER

PF00023 // ENSGT00760000119090_6_Domain_0 (197, 227)

GETPLHMAAIRGDVKQVKELIRLGANVNVK

ENSGT00760000119090_6_Linker_0_1 (227, 230)

DFA

PF00023 // ENSGT00760000119090_6_Domain_1 (230, 259)

GWTPLHEACNV
GYYDVAKVLIAAGADVNT

ENSGT00760000119090_6_Linker_1_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 293)

DDDTPLHDSASSGHRNIVKLLLRHGGNPFQANKHGERPV
DVAETEELEMLLKREVPISDDEDSCSDSEEAPSVNP-SSVDGNVDSEAEKDSVANKSKQT
VSSKAPLP--SALDEYEFKDDDE----DEMKKMIDDKHILRKDPRKEDETEVEKTSLFVK
QEK-VVLSKSFKNKKQKPSRVL-YSSSESSDEEILQDKKMVS-PCSVSETSNSDVRVKKE
YMVTNEHKQKGKVKRKVKNQSKNKENQEVKQEKENA---RVTNIA-TSGLDSLDKAREEE
TFKKSFTSKEDSSLQLFHITAGKSPKHPCGLSEKQSTPLKQENTKTCLSP-GGSEITLQP
ELVRYDHNTDSDYLVESSSGKSCKHKEKSKHHQKDFHLEFGEKSSPKIKEEDNSSAFENS
EYTLRKIDKEGKTLKKHKLKHKEREKEKHKKEQDGEREKHKHKDNVREVQRSIEFDREFW
KENFFKSDENDDTLINAEHESLSSDRKSKL---EKTVAKEDKLVKEKQFQKERSIKDERE
KEKNKKENEKFLKDEKTKDTKEEKE-VTPADKE--IELFCFG--VKDEAAIVHIVE--TD
TEKQEKNLKENKEKTEKRFSIKEKDIEKVERKHGEKEKKLKHEYKVEKEKAEVNENTEKV
KEKSN--FQQAERCHKENDKVKSMSAFKKVDDKERNKEKTDKKHDKEKADKDRHWAESKE
KHCTERKVKQSEKESEYTKSEKNRSKEK--ESEKKDKSKDKETSSLASSKHVQEERR-CT
ITESNKTVHDKLSSLKEKTKDDLLKIPDGREKDKKD--KDIDRYKERDKHKDKLHQSGLL
KLK---LEHEKLKPKP----APAPKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHR
KHKEKIKQKEKERLRNRTCSEHN--KMKEKPKHSIADVKGKELIRSKSSELPDVCMKEKQ
QKDATSNRSQSVDTRSVSVAKP--SLA-LDNS--NRSPKSESEKIGLSSRSVSMVSVASS
EDSCHTTVTTPRPVIEYDSDFMPEGSDSQMSFSQSPFLASAKSPALVEKEADGLAELPDH
IKPPFTNRLPQMYVRSA-SAEDVKLVLNECRPVIEVRRCSMPAAVS-EHSKQPR--TSEE
NSQNAL--PSAQTHG-STSPKPEL-LCSTLERDFQSNVTVLQSN-FTSSPNRAVSSKQAT
-MGTSTIKDTAQMSPSDNSNMHLEPCSQSGVTQQTKPWDVPFDRLNSLNSDSNSSGCGVS
EQD-PKIIIAVHN--SESRALKEQQVSEFLPQH-PEIKGGSSSQESAEF-LPSQSPCSLP
I-QPLP----VVSKHVFLPGMVSQDSALVQQQ----NVIQIATSALDTDAISTRELENAL
FPSNIKMTDASMAVYSESSVKDISQSYERVNDLPIVPLEKDTPESDSSSQLNVNLYSSSK
VVCKDAVGE-VDANTADTSDIRNEKDQQ-EKLVSVHVVDSGANADLCELRS--GMSKGIT
NELVNKSPCTADRENVLA--GDPPQYSSLSNLENSSQQIAQEEVHKYSQIVKVEEEV-AE
DQKMEQQEVPQRITRNRANLLANQGKQNPLGCTQTSEKES-ESSASMKARIRLTEDDDAQ
VHHPRKRKVSRVPQPVQANPSLLQAKEKTQQSLAAIVDSLKLEEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFKQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDAQTDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI

MPRSGFPKPVQSENSDSDS-NMVERPYGRKSKDKIASYSKTSKIDRGDIGKEMKEKPSMK
RKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRT-YSEKEGPEKKKTKKEAG-S
KKSTPVSILFGYPLSERKQ------MALVMQMTARDNSP--DSTPSHPSQATPA-QKKTP
SSSSRQKDKI

PF12796 // ENSGT00760000119090_6_Domain_0 (191, 259)

NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNV
GYYDVAKILIAAGADVNT

ENSGT00760000119090_6_Linker_0_2 (259, 262)

QGL

PF00023 // ENSGT00760000119090_6_Domain_2 (262, 291)

DDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV
DVAETEELELLLKREVPLSGDDESYTDSEEAHSVNP-SSVDENIDSEPEKDPFICESK-V
LPSKAPLP--SALDEYEFKDDDE----EEIGRMIDDRHILRKEQRKESELEAEKSGLFAK
QEK-AFYCKSFKAKKQKPSRVL-YSSTDSSDEDLLQGSKRASTTCSVPETSSADTQARRE
YE----YKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTALDCSEKTREEG
NFRKSFSPKDDTSLHLFHISTGKSPKHACGLSEKQSTPLKQEHTKACISP-GSSEMSLQP
DLARYDT-TEPEFLPENTNLKSYKHKEKSK-HQKDFHLEFGEKSNAKMKDEDHNPTFENS
ECTLKKMDKEGKTLKKHKLKHKEREKEKHRKEADSEKEKYRNKGNPEELQRGIEFDREFW
KENFFKSDETEDLFLNMEHESLT-EKKSKL---EKNM-KDDKSTKEKHVSKERSFKEERE
--KTKKESEKSLREEKL---KEDRD-SMSTEKD--VECGSVGIALNQESVGPHSAEKEMD
IEKQEKHTRE-REKSDRRFQTKEKEVEKTERKFSEKEKKMRHEHKSEKEKWDFSENVDRI
KEKDKLWSQQTERCQKEGEKTKNT--VKKTDDRERNREKVDRKHDKERPEKERCLAESKE
KHLEKK---KCD-NSEYTKSEKARN--KDREGEKKEKFRDKESINITNSRHLQEEKRSSI
GDSSSKIQHEKTVSLKEKARDEPLKTPDGKEKDK----KDIDRYKERDKRKDKIQLNTLI
KLK---SETDKPKPKS----SPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHK
KHKEKIKQKEKERLRNRTCLELKVKDKDK-TKHTPTESKSKEFARSRSSELTDAYNKEKQ
SKDAGSNRSQCVDSKNVLNLGKSPFIP-ENSS--NRSPRSESERLGLSSRSVSMISVASS
EDSCHT-VTTPRPPVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELESLADLPER
LKAPCTNRVPVCHLRSS-SVEDVKVIPSEARPAVEIRRCSMPSVIC-EPTKHFQ-IPE-E
SAQ-GS--LAVPRET-CPSPKPEVS-SAVPERGLPH-VSEFHPN-LAGSPTRSVNSRYIS
-SDTNVIKSVSLVGTLMDSPMNLEPSNQVGV-IQNKSWEMPAEKLESLSTNDLICPDPST
SDQ-DSSAQSFCH--SENKTLREQNTD-CLSSPQTEMPGKSCAQDAASL-LSSLQPCSFS
N-QAHSDA-ESASKAVSLSCGASQEPGVLQER----NAGHVISSVLDSDNNFTKEMENAF
VLADIQKTNSFVPVYSESTVQETLASFEKASTLLVLPSGKDFSGSDGASQMS-TQYTFSK
LTYKSSSSHQVEKSIDDTQVTSHEKEKRLQGLVLTQL-S-KCDSDLYGMDA--GMPKGSL
SDQDPAKHSPGSEKYLLPIEDEESQQSPLSSVESHSQPSAQPELHKYDQLTKGDLEESAE
DDKT-ENQHPQRLTRNKVSPVVSQSKQILAGCTLLPEKDS-D--SSPRGRIRLTEDDDPQ
IHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYL
HIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLK
ELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAE
VYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQR
LEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI