Query Results 

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------------------------------------K--TAGINKRHARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLVKALIESGADVNLKDNAGWT--PLHEAASEGCNDVIVELLKASANVNCENVDGIL
PLHDAVANSHLKAAEILLQHGANPNQKDQKQKTALDKADDENMKDLLKSYGAIETHNRDE
TDAVV-T--VPA--IRLKKQKQ---CFCEDCKT-FDTHSLSH--QKKTEENLPVHQTISS
ILQDIEEKQENLLQFEIRTPEDAEQYIDKMLKIKEVMDDVLAKQKAERDD---LAKKY-R
VSIESFKHGVLREQLANLATRQKSLLLVAKKQKEISQKIHNYKNVTSSSDHSFRKLPCSS
EICNEKDSR-EFAGLENSVQPQSG-----SLSPVRPVCGSM-----------QKTQLCLE
IWHDRQNNN-TSPKS-----KTVRREEFCGNEMNSKRNVN------------DCTSNGLS
KCRHSDGTKKIKLSSHPVNFIAQAEHSQK--ES-DLTDTTAQGHAS--F-GPSALIGTLN
VSETTSLLDHSDAHPSAVIYDQALCSCDLK-KGSRKTASQQPSRGTSESL-----AHQES
DVF-FG-SNTGHQVKPYPK-KSLLAVPHADGSQSSSSSGSGRQN-TIKKPLNSSTSPKKK
RMQIKDLILLGRINPGNNILEFKTQDTTHKASVLLSGKIKVENGQIYQNPVTWLKDLLGG
ESYVTWNYAWSKITYQGKELIKYVSEELPMPPDPDVLPQQHQPCLSGT------------
---------------SGGSMQSIPQYLH-INEILLISDQEFLPCHIMDKHWKFYVECEEL
TF----

MEEGVQAPDWDSDETVIEGSVTESDLEEKELPWRRLLFDQDASLKSEFSLHPDTRGMCKG
-MPSPEIQLGFKL--REDLQEQMNKNKMMPVLSEDTILQS-QDET--ERNQALLQTRKNC
SMFIGSFRQSGLSLNH-----------QNIEGPEA-ESP-----EV---LPHIEKELSEG
RDSPEVSLLSGAAITVSDTVAVKETSLVEPEKILAAPNTFFEPRK-EVTMTMTSEETKDE
ESSLETFVSALESLLTSPESTQEERL-------------FELVSDFDCKELMNPLSDSLS
SISI-PLNSWSACH-----RDLLENAK-DDALPAELLE-ALNTLSEAKVETICHRKEGGS
SLIAR----NEC--L------------EVEFNTSQ-TNEDCTQIA-----ETLQDPNPSG
LQTLAHQNITSCEPLSNKRNSNSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEK----NMHSAR
------FKNGK-QIRKNEQLSG---KKEKMKVNKISLRSINRRNIFGENLVYKAALHDDA
DLVHHCIKKGGNVNQPSYA---

PF00023 // ENSGT00760000119090_5_Domain_0 (623, 652)

GWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPL
HDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKASLFI--NKE
DVYEYYQKDPQNTKFGKSKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
HKRTQADD-VD---CNPRKILAVSPSRRINRLVTYQQHIPETHNDLPEELCEPSSLTLSS
L---KNGLDSSTEACSVSKEIH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLLLHKEIKLPVVTTDKQPHTLQEQ-HHVLYKSHENSNLVPKDER-FNKWE
NSFLSFVKENSDN-D---DGDDCSTSEKAITSKKVLCSTGGKKHYNFKENLTNKKEMGFQ
QFLLSED-HLSQENELKAVSLTTLPEQEAVNFSYSDNAVISE-HVANYEQCIFGPSFDHS
NGNPEQNSLACMRTF-LTHEASKLTNHVELFKKPQDY-IPRAPTFLMNQTDTHIVEKVA-
--KNCDTERNYIDRDQKIIYSNEPLSIVAHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMSKELANISKL-SQREKKEIS------------------------HKPDEELTNNISG
DEITIRNCEEIKEKTESEIHMPTNSQEHKTVQ-NFR-KRQSFLKTTCNLGM---------
------------------------------------K--TGGINKRNARGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAVRR
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKVNCENIDGIL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLRSYGAIETVNRDE
SDAIV-NEKIPA--VQSERHKQ---CFCDDGKT-IDSSSLSH--QERSSESLSVHQTLSA
ILQDIEEKQEYLLEFEIRNPEDAEQYIEKMLKIKKIMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLAARQKSLLVVAKKQKKISLKIQNCKNVTSLPCLSLRKLPPRS
EISSEKDSQ-ELTSLENLEHPQSG-----SLSP---VSGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDMNSKQNVS------------DCTLDGFP
KSRHSDGTEKNKLPSQPVAFIGQTEYSQK--EN-DLTEATDKDHEF--Y-VSSPVIGKLN
ISETASVLAENAAHPSNIICDQDLSNYDPK-RGNRKTSSQQSPTGASESL-----AHQGI
A-V-LG-SDTVHQMKPYLK-KSVSVVPCADDSQISSSSGSGQQD-TIKKALNYSRAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPIRPEPNSVPQQYQPCLPEVACLDDPV---QE
PNKSMFEKTKFGQGTSRESMQSIPRYLQ-INEILLISDQEFLPCHIMDQHWKFCVECEEL
TP----

MEGGAQVPDWDSDETVIEGSVADSDLEDEELPWRRLLFDRDTALTSEFGLHLDRSGGYKG
-APSPEIQLGCKL--RDNS-QQMNENKMMPILSEDSVLQA--------------------
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----------------------------------------------------IENSNPFG
SPSLAHQNVTSCEPLNNNKNPNPMDN----ASDQKTPRVLRRSSR--LEKLKVSQGA--K
YTDDMYK----MPEKTVSEIRSCEDQISNKST-ENFS---------QNSK----NMHSSR
------FKGE--QIRKNERLMLKKG-----EINQLPLSSINRRNIFGENVLYEAVLYDDA
DLVHYCIKKGANVNQPSYA---GWTALHEASVGGFYRTANELLKGGADVNVRGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 682)

ITPL
HDAVINGHHEVAELLLLNGAD

ENSGT00760000119090_5_Linker_1_3 (682, 1434)

PLFRRDNGKSALDEAKDS-RMKRLLEKYVPKYQKHLTSD
QRKSTGPGDEDDVHQHKKPKFSPKNHTGFVCNENSSSPKPEHVEVNKRSKEGVFIN---E
DVYEHYPQNSRITRFGKSKD-----------------NLCNRKDTSANV-SKVKGRKNTQ
DKRTQSDD-RE---CSSGQAIAVSSSRRINSLVTCQQDIPQTLNGLPEESYEPSSPTLSS
L---KDGLGNKDEVYSISKEVH-----------------T-HHLNLLEGQEIQFLGLDYL
DQTEAGSFSGRSLHKEVNLPLVSADPQPHVYQEQ-QTTPDKSHKNSNSGKKNKT-FNKWE
SSFLSFIKDNYDDL--------------------------CKNI--YEGNLRNREEGDFL
QFLPSEV-HFLQENELREGFLTTLPQQEAVNFSDLGKVVISEQRVANYEQCIGGTSFDHS
VGSTEQTSLACTRTL-SIQEVLKLTTHVELLKKPQDN-SPRELASLMNQTDAHIMEKVM-
---KEDTERNYSDNDQK----QRLFPTAVHCQEIEITNVEIEKPDLPESEPMPDTNLCST
HNVNKELTDISEF--NQKEKEIS------------------------HKPDEELTNNINE
DENIVTNCLEKKEKIDSGIYITPHVQEHEKDQ-NFG-KRQSLLKATCNQGL---------
------------------------------------N-KTTGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1516)

LHSAAKR
GDLSLVKVLGESGADVNLKE--CWT--PLHEASTEGFSDIIVELLKPGANVNCESTDGIL
PLHDAVAGSHLKVAEIPPQHGGNSNQKDQTQKTALGEANNEKMKELLKSYGATKTNNEDD
NNAAV-TVKSPT--VGSKRYKQ---CFCDDDKT-VDAPSPSH--QEKGRENFPVHQTISA
ILQDIEENQEKLLEFEIRNSKDVEQYIEKMLEIKEIMDNVLSKQKAERDD---LAKKY-R
VSIESFKHGVLREQLANLATRQRRLLVAAKKQKNISLKIQNYKNITSVSGSHLRKLPSSL
DISSDKEGR-ELNNLENLVQPQLS-----PFSPVNLDCGSV-----------QETPLPPE
SQNHGQNTN-ICLNS-----KAVKR-KYSRDEMNSKQNEN------------DCTLDDVS
KSRHSDSTEKIKLSSQHVTFIAQAEYSQK--EN-DLTETIAKDHEF--C-SPSATTSTLS
ISECSTVLSQNDAHLSTVISDQDLSHYDPK-RGNKKTASHLPPDGASESL-----AHQKS
A-V-ID-TDPGHPIKPYLK-KTASTIPRANDRPISSSSESAHQH-AIKKPSSFSTTPKKK
CMQIKDLILLGRIKPGNNILEFKTQETTHKASILLSGKIKVENGQIYQNPVTWLKDLLGG
DSYVTWNYAWSKVSHS--------------------------------------------
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------

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------------------------------------TTGESKKRKKNE

PF00023 // ENSGT00760000119090_5_Domain_2 (1429, 1461)

KGETKLHIAARR
GNLSLVKTLISSGILVNEQD

ENSGT00760000119090_5_Linker_2_3 (1461, 1462)

N

PF00023 // ENSGT00760000119090_5_Domain_3 (1462, 1496)

AGWT--ALHEASNGGFTEVILELLKAGANVNSRN

ENSGT00760000119090_5_Linker_3_4 (1496, 1497)

M

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1529)

DGVL
PIHDAVSGNYLEAARILLQHGANPCERDSSGKSALDEACDDEMKELLKSYGAIDSVLPVA
TAEVT-GKETNC--LRVRRPKSCSECCKNDDA------ALKR--QNE----KSCVE-SVV
AIQDTKKKQKELLLLELRTSKDADAYVQRLCQIQNTLNEMFAKQKTERDA---LAKKY-R
ASVESFKKGALREQVVNLASRQKSLLTVAQNQEELVQKIQNYRKTKQVFRAAQLEHQFSN
TVFSYGNGKGPGLAADEIMHPDVVTSDTGLGASMPNGNRVEAHLSLENRFSAQECSQHPN
NCLAEREAN-----K-----EAIRSKEVSDHTSTSKKTIR------------KYPF----
-NTLSNAVEVVTVSSETAGSTTQTKNSQQ-NNI-DCVAVAEQGNKS--L-HPTSVTNTLN
ISEARSTVVNNNVCQPGSDCQWVLTDEDLRRYVNKKEVFQQQHQQCSENP-----FNDN-
L-V-LT-NLT-------------SNTDYPASLSKKSSQGYSYQE-CEQKQVKYER-KNKK
KLQLIDLLQLGRIKPGENVLEFKLQEFSHKATLLENGKIKTSENKILQNPVQWVKDLLGS
DISVTWKYVWNKVMYHGTQLSKLLVEEVPASNDLELPSQQREPLDREKKLLEDPI---KQ
RNPRKFYKLQFGSELSKSQFNSVESLTQVVNETLLLRTEEFLPWSVMEKHWNFYLACEDF
GF----

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------------------------------------K--TAGISKRHARRESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAATR
GNLSLVKALIESGADVNAKDNAGWT--PLHEASSKGSNDIIVELLKAGANVNCENVGGIL
PLHDAASSSHLKAAEILLQHGANPNQKNQKQNTALDEADDEKTKELLKSYDAVETDNRDE
SNATV-TVKIPA--ARPKRHKQ---CFSDDCKS-VDPPFLSR--RGKTRESHPVHHTISA
ILQDIEEKQESLLEFEIRTPEDAEQYIEKMLEIKDVMDNVLAKQKAERDD---LAKKY-R
VSIESFKQGVLREQLANLATRQKSLLVVAKKQKKISQKIQNYKNITSASGPGLKRLPSSS
EISSEKDSQ-RLTSLGNSVQPHSG-----SCSPVSLICGSI-----------QETQSSLE
TWNGSQNTN-TCVNS-----ETVRREEFFGNELNSKQNVN------------DCTLDGLS
KSRHSDGTKKIKLPPQPVAFLAQAEYSQK--EN-HLTETPAKGNES--YSSPSAVTGTLN
ISETTSRLAENDAHLSTVICDQAPTNCDPK-RGNRKITSQQPPRGTLESL-----AHQGT
D-A-LG-STTGHQMKSYLK-KSVFAVPHAHDGESSYSSGSGRQH-IIKNPLNNSTAPRKK
CMQIKDLILLGRINPGNNILEFKTQETTHKASVLLSGKIKVENGQIYQNPVTWLKDLLGD
DSYVTWNYAWSKVTYLGKELVKYVSEEIPVPSEPNMAPQQHQPCLPDAPCLDDLVLEKM-
---------KFGQGTSRESMQSIPHYLQ-IKEVLLISDQEFLPCHIMDQHWKFYVECEEL
TF----

MEEGAQTPDWDSDETVIEGSVTENELEEEELPWRRLLFDEDTSLRSAFSLHPNINGICKG
-TPSPKIQLGFQL--REDLQGQMNKNKMMCVLSEDTVLQP-QDET--EQNKALLQTRKNY
PMFTMSFPQTGISLNH-----------QNIGGPEA---------ENPEVLSHLEKDLSED
EDSPEVSLLSSTAVMVSEVVAIKEKSLIAPEKILAAPNTFSEPGK-EVTLTMTSEETKDE
ENSLETFVSALERLLTSPESSQEERL-------------LEIINDFDHKELMNPLSGSPS
SISI-PLNALSACH-----RDLLGNTK-DDALPAELLA-ALNTLSEAKMKPIRHRKEGGS
IINAG----NEC--L------------EVEFNMSQ-TNEDGTQTA-----KNLEDPDSFG
LQTLAHQNVTSCEPLNNKGNSNLVEN----SSDQKTARVLTRSSR--LEKLKVRRDA--E
HTDDMYK----MAEKILPKKLICENLTSNNSSTENFRMPDPALMIEAKGK----NMHSSR
------FKSGE-QIRKSKRLTG---KNEKMKMNELSLSSINRRNVFGENLLY

PF12796 // ENSGT00760000119090_5_Domain_0 (593, 682)

KAALHDDV
DLVRHCIKKGGNVNQPSNA---GWTALHEASVGGFYQIASELLKGGADVNNKGMYQITPL
HDAVINGHYKMTELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFRSDSGQCALDEAKDS-RMKRLLERYVPKHQKYLTSA
QRNSTNPLDIEDVHQHKKPKFSSKNRIWFVCNENSNRQKPEHIKINKGNKEGLFIN--KE
DVYECYQKDSENTKLCKSKHKQSTGNQIYST-GLRKGNLHNIKDPSTKL-SKGKGRRNTQ
HKMTQADD-GD---SNPRKALAVSSSRRMNRLVTRRQHNLQTIDDLPEEAYEHSSPTLSS
L---KNELDNNIEACSVSKETH-----------------I-QSIDLSDSQEAQFLELESV
DQTEAVSLSGLSLHKEIKLPLVTTDQQPHTLQEQ-HSSPYKSHENSNSVEKDESLINKWE
NSFLSFIKENFDDDDDDDDDSDCSISEKSVTFEKVICSTDCKNHCNDKENTTNREEMAFQ
QFSPSEG-HLSQENELKAGSLTTLPQQEAVNFSDSDNTVISEQHVTNFEQCVYGTSFDHS
NSNLKQTSLACMRTL-SKHEVSKLTSHVELFKKPQDY-SPGAPAPLMNQTDVHIVEKVT-
--KKQDTERNYTDKGQKTSSLNGPLSTVVDSQVTEITEIEK-RQNLPENRTIHNIDFHST
DHINKELTNITPL-GQREEKETS------------------------HQPVEELIYNING
DEHNTRNCKEKK-KTESEIHIPTNTQEHRKVQ-NFR-KRQSFLKATYNQGM---------
------------------------------------K--TAGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHVAARR
GNLSVVKALIESGADVNLKDNAGWT--PLHEAAHEGSADIIVELLKAGANVNSENLDGIL
PLHDAVASNHLKAAEILLQNGANPNQKNQKQKTALDEADDEKMKELLKSYGAIEINHREE
SNVTI-NVEIPA--LRLKRHKQ---GFCGDGKT-VDPPSFSH--QGETRENLPVHQTLSA
ILQDIEEKQENLLAFEIRNPEDAEQYIEKMLKIKEIMDSVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLATRQKSLLVAAKKQKEISLKIQNYKNVTSLSGLGLRKLPPSS
EISSEKNIQ-ELNSLENSVQPQSR-----SLSPVSFVCGSM-----------QETQLPVE
AYNYSHNTT-ICLNS-----ETVRREEFSGNKINSKQNVN------------DCTLDGLS
KSRHSGG-TEIKLPSQPVVFIPETEYSQK--EN-DLTETTAERHEF--Y-SSSAVTGTLD
ISETTSALAQNDVHPSTVVCDQDLSN-DPK-RRNRKAASQQPPRGASESL-----AHQGI
A-V-SG-SDTVHEMKACLK-KLASAVPHVNGSQNSSSSGSRHQH-TVKKPLNYSTAPKKK
CMQIKDLILLGRINPGNNILEFRTQDTTYKASVLLSGKIKVENGQIYQNPVTWLKDLLGG
DSYVTWNYAWSKVTYLGKELLKYVSEEVPILPEPNLVSRQHQTCLP--------------
------------------------------------------------------------
------

MEEGVQDPDWDSDETVIEGSVTESDLEEKELRWRRLLFDQDTALKSEFSLHPDTRGVCEG
-MPSPEIQLGFKL--KEDLQEQMSKNRMMPILSEDTILQS-QDET--ERNQALLQTRKNC
SMFIGSFHQSGLSLNH-----------QNSEGPEADETP-----EV---LPHIEKELSDG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAAPNTFFEPRK-EVILTVTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------FELVSDFDRKELMDPLSDSLS
SISI-PLNAWSACH-----SDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EVKFNTSQ-TNEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCEPLSNKRNSHSVTN----SSDQETAYVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMVDSKEK----NMHSRR
------LKNGK-QIRKNEQFPG---KKEKMKVNKISLGSINRRNIFGENLVYKAALNDDA
DLVHHCIKKGGNVNQPSYA---GWTALHEASVGGFYRTASELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVMNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEHYQKDPQNTKFGKSKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCILETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKETH-----------------I-QNLDLSDSQEVQCLELESI
DQTEAVSFPGLSLHKEITLPLVTTDKQPHTLQEQ-HHVLYKSYENINLVQKNER-FNKWE
NSFLSFVKGNSDND-----DDDCCTSEKAITSKKVMCSTGCKKHCNFKENLANRREKDFQ
QFLVSED-HFSQENELQAVSLTTLPEQEAVNFSHSDNAVISE-HVANYEQCIFGPSFDHS
HGNPEQNSLACMRTL-STHEVSQLTNHVELFKKPQDY-IPREPTFLMKQADTHIVEEVA-
--KNCDTERNYTDRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPGM--------
-----------------------------------------------KT-----------
----------------------------------------GGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARK
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKVNCANIDGTL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLKSYGAIETDNRDE
RDAIV-NEKIPA--VQSKRHKQ---CFCDDSKT-IDSPFLSH--QERSSESLSVHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLNIKEIMDNVLAKQKAERDD---LAKKY-R
ISIESFKHGALREQLANLVARQKSLLVVAKKQKRISLKIQNYKNVTSLPCLSLRKLPPRS
ENCSEKDNQ-ELTSLENLEHPQSG-----LLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDVNSKQNVS------------DCTLDGFP
KSQHSDGTENNKLPSQPVAFIGQTEYSQKEKEN-DLTEATDKDHEF--C-IPSPVIGKLN
ISETASVLAENAAHPSNIICDQDLSNYHPK-RGNRKTNSQQSPTGASESL-----AHQGV
A-V-LG-SDTVHPMKPYRK-KSVSAVPRADDSQISSSSGSGQQD-IIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKSPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFGQGTSREPMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFYVGCEEL
TL----

--------------------------MPLFFVFERFLFDRDTSLTFEFGLHPGVSGMYKD
-TSSPEIQLGCKL--REDSQEQMNKNKVMPILSEDSVLQQPQDET--EQNRGVLQTTTNF
AMSTVSFPQDGFSLNQ-----------QNFGGHEA-ENT-----EV---LPYLEKELNED
RDSPEISLLSNIATTVSGMVAVKEKSLIEPDKILAAPNTFYDPGK-EITLTMTSEETNDE
ESSIETFVSALERLLRSPESTQEKRL-------------FEPMNDFDPVELMNPLSNSSS
SMSI-SLSALSPYC-----RDLLANTE-DDALPPELFT-ALNTLSGDKAGPIFHSKKEGG
SLRDR----NEY--L------------E--PDTFQ-TNEDCTQIT-----ETVKDSNPFG
CPNLAHQNVSSCDPLNN-KNPNPMDN----GSDHETPRVLRRSSR--LEKLKVSQDA--K
CTEDMCK----IPEKIVPKMHSCEDQIKNKS-IENFRMKAPVLMIEDKKK----NMQSSR
------FKGE--QIRKNERLIL---KKEKLKINKMPLSSINRRNIFGETLLYKAALYDDA
DLVHCCIKKGANVNQPSNA---GWTALHEASVGGFYRTANELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 686)

ITPL
HDAVVNGHHKVAELLLLSGADPLIR

ENSGT00760000119090_5_Linker_1_3 (686, 1434)

TDSGKCALDEAKDS-RMKRLLEKYVPQCQKRLISD
QRKSIDPGDVEDVHQHKKTKFSPKNHTGFDCNENINRQKPENVEVNKRSKEGLFIN---E
DIYECYPKNSKIIKFGKSKHKQSTLKQTYCT-GLRKGSVCNIKDSSTNM-SEGKGRKKTQ
DKRTQAND-GD---CTSRQAVGISSSRRINAVGACQQH----LDDLSEDSHEPSSLTPSI
L---KDGLVNNVEICSVSKEAH-----------------AKHHLDLPEGQEMQFFGLEYI
GQTESGSFFGPALHKEVKLPFVSTDQQPHVYQEQ-QSSPYKSHENSNSGEKNKT-FNKWE
NSFLSFIKEHSDNY-----NDNFCISEETITSEMVTCSTECKNHYQE---NLNREERDLQ
YFLPSED-HFPQENELKESSLTTLPQHEAVNISDSDKAVISEQHVANYEQCIYGTNFDHL
FGNPEKTSLTCTRTL-STHEASKLTSHVEILKKPQDN-SPSESTPLMNQIDTHIMEKVYV
ELKDDDIKRNFSDKGQK----PRLSPTVVHPQEIEITNVEK-KQYLPESESITNTNFCST
NNMNKELTNISEF--NQQEKEIS------------------------RKPGEELTNNINE
DESIVRNYEEKKEKIDSEIYMPPNTQEHKK-E-NFR-KRQSCSKATYNQDM---------
------------------------------------K--TTGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHSAARR
GDLSLVQILIESGADVNLKDNAGWT--PLHEASNEGFSDIIIELLKAGANVNCESIEGIL
PLHDAVAGNHLKAAEILLQHGANPNKKDQTQKTALDQADNEKMKELLKSYGALETNNRDE
SSAAV-TVKTTT--TRSKRYKQ---CLCKEDKT-VDPPSPSH--QEERRENFPMQQSISA
ILQDIEENQQKLLEFEIRNSKDAEQYIEKMLEIKEIMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGVLREQLANLATRQKRLLVAAKNQKNISLKIQNYKNTTSLPGLHLRKLSSSL
DISSDKGSQ-ELTRLENLGQLQ---------DPVHLDCGSV-----------KETALSPE
TWNDGQNTN-ICPNS----------RGFSRNEMNLKQDNG------------DCTLDDFS
KSRHSHNTEKIKSSSK-HVFIVQTEHSQK--EN-DRSEKITEDHEF--C-SS-SATSTLN
ISECTISLSQNDAYLSTVISDQDLSHCDPK-RRNKKTASQLPPGGVSESL-----AHQSS
A-V-LG-TDTGHPIKSYLK-KTASAIPCANDRQISSSSESGHRH-NIKKPLSFSTTPKKK
CMQIKDLILLGKIKPGNNILEFRTQETTHKASILMSGKIKVENGQIYQNPVCWLKDLLGG
DSYVTWNYAWSKVTYLGKELLKYVSEEVSLPPELDIVSQQHQTCLPG-------------
--------------SSSESLQSIPYYLQ-INEILLTSDQEFLPCHLMDQHWKFYVECEEL
TF----

MEEGVQAPDWDSDETVIEGSVTESDLEEKELPWRRLLFDQDASLKSEFSLHPDTRGMCKG
-MPSPEIQLGFKL--REDLQEQMNKNKMMPVLSEDTILQS-QDET--ERNQALLQTRKNC
SMFIGSFRQSGLSLNH-----------QNIEGPEA-ESP-----EV---LPHIEKELSEG
RDSPEVSLLSGTAITVSDTVAVKETSLVEPEKILAAPNTFFEPRK-EVTMTMTSEETKDE
ESSLETFVSALESLLTSPESTQEERL-------------FELVSDFDRKELMNPLSDSLS
SISI-PLNSWSACH-----RDLLEDAK-DDALPAELLE-ALNTLSEAKVETICHRKEGGS
SLIAR----NEC--L------------EVEFNTSQ-TNEDCTQIA-----ETLQDPNPSG
LQTLAHQNITSCEPLSNKRNSNSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEK----NMHSAR
------FKNGK-QIRKNEQFSG---KKEKMKVNKISLHSINRRNIFGENLVYKAALHDDA
DLVHHCIKKGGNVNQPSYA---GWTALHEASVGGFYRTASELLKGGADVNIKGLYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVMNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKASLFI--NKE
DVYEYYQKDPKNTKFGKSKHKQSTLDQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
HKRTQVDD-VD---CNPRKILAVSPSRRINRLVTYQQHIPETHNDLPEELCEPSSLTLSS
L---RNGLDSSTEACSVSKEKH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLLLHKEIKLPVVTTDKQPHTLQEQ-HHVLYKSHENSNLVPKDER-FNKWE
NSFLSFVKENSDN-D---DDDDCSTSEKAITSKKVLCSTGGKKHYNFKENLTNKKEMGFQ
QFLLSED-HLSQENELKAVSLTTLPEQEAVNFSYSDNAVISE-HVANYEQCIFGPSFDHS
NGNPEQNSLACMRTL-LTHEASKLTNHVELFKKPQDY-IPRAPTFLMNQTDTHIVEKMA-
--KNCDTERNYIDRDQKIIYSNEPLSIVAHSQVIETTKVEKRRQNHLESETIHNIDSHST
DNMSKELANISKL-SQREKKEIS------------------------HKP----------
-------------------------------------------------GM---------
------------------------------------K--AGRINKRNARGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAVRR
GNLPLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKVNCENIDGIL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLRSYGAIETVNRDE
SDAIV-NEKIPA--VRSKRHKQ---CFCDDGKT-IDSSSLSH--QERSRESLSVHQTLSA
ILQDIEEKQEYLLEFEIRNPEDAEQYIEKMLKIKKIMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLAARQKSLLVVAKKQKKISLKIQNCRNVTSLPCLSLRKLPPRS
EISSEKDSQ-ELTSLENLEHPQSG-----SLSP---VSGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDMNSKQNGS------------DCTLDGFP
KSRHSDGTEKNKLPSQPVAFIGQTEYSQK--EN-DLTEATDKDHEF--Y-VSSPVIGKLN
ISETASVLAENAAHPSNIICDQDLSNYDPK-RGNRKTSSQQSPTGASESL-----AHQGI
A-V-LG-SDTVHQMKPYLK-KSVSVVPCADDSQISSSSGSGQQD-TIKKALNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLRYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PNKSMFEKTKFGQGTSRESMQSSPRYLQ-INEILLISDQEFLPCHIMDQHWKFCVECEEL
TP----

MEEGVQAPDWDSDETVIEGSVTESDLEEKELPWRRLLFDQDTSLKSEFSLHPDTRGMCKG
-MPSPEIQLGFKL--REDLQEQMNKNKMMPILSEDTILQS-QDET--ERNQALLQTRKNC
SMFIGSFRQSGLSLNH-----------QNIGGPEA-ESP-----EV---LPHIEKELSEG
RDSPEVSLLSGTAITVSDTVAVKETSLIEPEKILAAPNTFFEPRK-EVTLTMNSEETKDE
ESSLETFVSALERLLTSPESTQEEKL-------------FELASDFDRKELMNPLSDSLS
CISI-PLNAWSACH-----RDLLENAK-DDALPAELLE-ALNTLSEAKVETICHRKEGGS
SLIAR----NEC--L------------EAEFNTSQ-TNEDCTQIA-----ETPQDPNPSG
LQTLAHQNITSCEPLSNKRNSNSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEK----NMHSAR
------FKNGK-QIRKNEKFSG---KKEKMKVNKISLGSINRRNIFGENLVY

PF12796 // ENSGT00760000119090_5_Domain_0 (593, 683)

KAALHDDA
DLVHHCIRKGGNVNQPSYA---GWTALHEASVGGFYQTASELLKGGADVNIKGMYQITPL
HDAVMNGHYKVAELLLLNGADP

ENSGT00760000119090_5_Linker_0_3 (683, 1434)

LFRNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDTDDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
EVYEYYQKDPENTKFGKSKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGVGRRKTQ
HKRTQVDD-VD---CNPRKTLAVSPSRRINGLVTYQQHIPETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKEIH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAISFPGLSLHKEIKLAVVTTDKQPHTLQEQ-HHVLYKSHENSNLVPKDER-FNKWE
NSFLSFVKENSDNDD---GDDDCSTSEKAITSTKVLCSTGGKKHYNFKENLTNEKEMGFQ
QFLLSED-HLSQENELKAVSLTALPEQEAVNFSHSDNAVTSE-HVANYEQCIFGPSFDHS
HGSPEQNSLACMRTL-STHEVSKLTNHVELFKKPQDY-IPRAPTFLMNQTDTHIVEKVA-
--KNCDTERNYIDRDQKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESEAIHDTDSRST
DNMSKELADISQL-SQREKKEIS------------------------HKPDEELTNNISG
DEITIRNCEEIKEKTESEIHMPTNSQEHKTGQ-NFR-KRQSFLKTTCNLGM---------
------------------------------------K--TGGINKRNARGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKVNCENIDGIL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLRSYGAIETVNRDE
SDAIV-NEKIPA--VRSKRHKQ---CFCDDGKT-IDSSSLSH--QERSSKSLSVHQTLSA
ILQDIEEKQEYLLEFEIRNPEDAEQYIEKMLKIKKIMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLAARQKSLLVVAKKQKKISLKIQNCKNVTSLPCLSLRKLPPRS
EISNEKDSQ-EVTSLENLEHPQSG-----SLSP---VSGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDMSSKQNVS------------DCTLDGFP
KSRHSYGTEKNKLPSQPVAFIGQTEYSQK--EN-DLTEATDKDHEF--Y-IPSPVIGKLN
ISETASVLAENAAHPSNTICDQDLSNYDPK-RGNRKTSSQQSPTGASESL-----AHQGI
A-V-LG-SETVHQMKQYLK-KSVSVVPCADDSQISSSSGSGQQD-TVKKPLSYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PNKSMFEKTKFGQGTSRESMQSIPRYLQ-INEILLISDQEFLPCHIMDQHWKFCVECEEL
TL----

MEEGVQAPDWDSDETVIEGSVTESDLEEEELPWRRLLFDQDTSLRYQFSLHPDTRGMCKG
-MPSPEIQLGFKI--REDLQEQMNKNKVMPVLSKDTILQS-QDET--VRNQALLQTRKNC
SMFFGSFPQSGLSSNH-----------QNIEGPEP-ESP-----EV---LPHMEKELSEG
RNSPEVSLLSGTAIIVSDTVTVKETSIIEPEKILAEPNPFFEPRK-EVTLTVTSEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------FELVSDFDPKELMNPLSDSLS
SISI-HLNAWSSCH-----RDLQENVK-DDALPAELLE-ALNTLSEAKVETICHRKEGGS
SLSAR----NEC--L------------EVEFNMSQ-IHEDCTQIA-----ETLQDPNPSG
LQTLTHQNITSCQPLSNNRNSNLVTN----SSDQETAFVLRRSSR--LEKLKINRDA--K
YSDHMYK----VPEKILPKILGCEDLTD--SSTQNFRLQDPALMTDGKKK----NMHSTR
------FKSGGKMIRKNEQFSG---RKEKMKVKKIHLASINRRNIFGENLV

PF12796 // ENSGT00760000119090_5_Domain_0 (592, 683)

YQAALHDDA
GLVRHYIKQGGNVNQPSYA---GWTALHEASVGGFYQTASELLKGGADVNIKGMYQITPL
HDAVMNGHYKVAELLLLNGADP

ENSGT00760000119090_5_Linker_0_3 (683, 1434)

LFRNGDGKCALDEAKDS-CMKRLLERYIPKHQKCLTLA
QRNSTDPLDIEDVYQHKKPKFSSRSHICHVCNENYNRQKQELVKVNKESKESLFININKE
DVYEYYQKVSKNTKFGKSKHKQSTLKQIYST-GLRKCSIYDVKDSNTNL-PKGIGRRNMQ
SKRTQVDD-VD---CNPRKTLAVFPSRRINRLVTDQQHIPQTLSDLPEESCEPSGITLPS
L---KTGLDNNIEVCSVSKETH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLSLHKEIKLPLVTTDKQPHTLQEQ-HHTLYKSHENSKLVQKDES-FNTWE
KAFLSFVKGNSDND------DDFSTSEKAVISKKVMCSTGCKNHCNFKENLTNRKEMDFQ
QFLLSED-HFSQENEVKAVSLTTLPKQEAVNFSDSDNVVISEQCVANCEQCIFGPSFDHS
HGNPEQNSLACMRTF-STQEVSKLTNHVELFKKPQDC-IPRAPTFVMNETDTHIVEEVA-
--KNCDTERNYIDKDQKLSYSNEPLSIVVHSQVIETTKAEKRRQN-LESETIHDIDSHST
DTVNKDLVNISQL-SRREKKEIS------------------------HKPDEELTNNISG
NEIMTRNCEEIKEKTESEIHIPTNIQEHETVQ-NFR-KR-RFLKTTCK-GM---------
------------------------------------K--TGGINKRHARGKSR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLVKALIETGADVNLNDNAGCT--PLHEASSKGSVDIIVELLKAGANVNCENIDGTL
PLHDAVANNHLKAAKILLQNGANPNQKDKKRKSALDEADDETMKELLKSYSAIQTNNRDE
SDGIV-NEKIPA--VRSKRHKQ---CFCDDGNP-VDSPSLSY--QERSRESLSAHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLKIKEIMNNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLATRQKSLLAVAKKQKKISLKIQNYKNVTSLSCLSLRKLPPRS
EIFSEKNSQEELTTLENLEHPQSV-----SLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVIRGGFSGNEMNSEQNIS------------DCTLAGLS
KSRHSDGTEKIKLSSEPVAFIGQTEYSQK--EN-DLIEATDKDHEF--Y-SRSPVIGKLN
ISETASILAKSDAHPSNVICDQDLSNYDPK-RGNRKTTSQEPARRTSESL-----ARRRI
A-A-LG-SDTVNQLKPYLK-KSVFAVPHADDSQISSSSR------SIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGG
NSYVTWNYAWNKVTYLGKELLKYVSEDVSILPEPNSVPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFEQGTSGEPMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFCVECEEL
ML----

MEEGVQAPDWDSDETVIEGSVTESDLEEKELPWRRLLFDQDASLKSEFSLHPDTRGMCKG
-MPSPEIQLGFKL--REDLQEQMNKNKMMPVLSKDTILQS-QDET--ERNQALLQTRKNC
SMFIGSFRQSGLSLNH-----------QNIEGPEA-ESP-----EV---LPHIEKELSEG
RDSPEVSLLSGTAITVSDTVAVKETSLVEPEKILAAPNTFFEPRK-EVTMTMTSEETKDE
ESSLETFVSALESLLTSPESTQEERL-------------FELVSDFDCKELMNPLSDSLS
SISI-PLNSWSACH-----RDLLENAK-DDALPAELLE-ALNTLSEAKVETICHRKEGGS
SLIAR----NEC--L------------EVEFNTSQ-TNEDCTQIA-----ETLQDPNPSG
LQTLAHQNITSCEPLSNKRNSNSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEK----NMHSAR
------FKNGK-QIRKNEQLSG---KKEKMKVNKISLRSINRRNIFGENLVYKAALHDDA
DLVHHCIKKGGNVNQPSYA---GWTALHEASVGGFYRTASELLKGGADVNIKGLYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVMNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKASLFI--NKE
DVYEYYQKDPQNTKFGKSKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKIQ
HKRTQADD-VD---CNPRKILAVSPSRRINRLVTYQQHIPETHNDLPEELCEPSSLTLSS
L---KNGLDSSTEACSVSKEIH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLLLHKEIKLPVVTTDKQPHTLQEQ-HHVLYKSHENSNLVPKDER-FNKWE
NSFLSFVKENSDN-D---DDDDCSTSEKAITSKKVLCSTGGKKHYNFKENLTNKKEMGFQ
QFLLSED-HLSQENELKAVSLTTLPEQEAVNFSYSDNAVISE-HVANYEQCIFGPSFDHS
NGNPEQNSLACMRTI-LTHEASKLTNHMELFKKPQDY-IPRAPTFLMNQTDTHIVEKVA-
--KNCDTERNYIDRDQKIIYSNEPLSIVAHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMSKELANISKL-SQREKKEIS------------------------HKPDEELTNNISG
DEITIRNCEEIKEKTESEIHMPTNSQEHKTVQ-NFR-KRQSFLKTTCNLGM---------
------------------------------------K--TGGINKRNARGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAVRR
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKVNCENIDGIL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLRSYGAIETVNRDE
SDAIV-NEKIPA--VQSKRHKQ---CFCDDGKT-IDSSSLSH--QERSSESLSVHQTLSA
ILQDIEEKQEYLLEFEIRNPEDAEQYIEKMLKIKKIMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLAARQKSLLVVAKKQKKISLKIQNCKNVTSLPCLSLRKLPPRS
EISSEKDSQ-ELTSLENLEHPQSG-----SLSP---VSGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDMNSKQNVS------------DCTLDGFP
KSRHSDGTEKNKLPSQPVAFIGQTEYSQK--EN-DLTEATDKDHEF--Y-VSSPVIGKLN
ISETASVLAENAAHPSNIIGDQDLSNYDPK-RGNRKTSSQQSPTGASESL-----AHQGI
A-V-LG-SDTVHQMKPYLK-KSVSVVPCADDSQISSSSGSGQQD-TIKKALNYSRAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPIRPEPNSVPQQYQPCLPEVACLDDPV---QE
PNKSMFEKTKFGQGTSRESMQSIPRYLQ-INEILLISDQEFLPCHIMDQHWKFCVECEEL
TP----

MEEGPQGPDWDSDETVIEGSVAE------------------------------------S
-TLSPEIQLGGKL--REDS-QQMNKDKMMSILTEDSVLQV------------CSMTGNNF
AVFTVSSPQAGLSLEE-----------QNIEGKCT----------------------DED
KDSPEISLLSNSATMVSGIVAVKEKFLIEPEKILAAPNTVYDPGK-EVTLTMSSKETKDE
ESSLETFVSALEKLLTSPESTQEKRL-------------FETVNDLDPGELMNTLSNSSS
SLSI-SLSALSPYC-----RDLLENTE-GDAFPPELLA-ALNALSEDKTGTVCCRKEGG-
SLIGR----NEV--L------------EMEPDTFQ-TDEDCTQIT-----E---------
----------------------------------ETPYVLRRSSR--LEKLKANRDA--K
CTDEMYK----MPEKVVSNIYTCEDQINKSAENS-------------GYK----NMNSSR
------FKGE--QIRKNERLI---------------------------------------
----------------L

PF12796 // ENSGT00760000119090_5_Domain_0 (618, 682)

KK---GWTALHEASAGGFYRTAKELLKGGADVNFKGMYQITPL
HDAVINGHYKVAELLLLSGADPLFRSDNGKCALDKARDS-RMKRLLEKYIPKYQKLLASD
QRKGTDPGDVEDICPHKKPKFSPKSHTGFVCNENSSRLRPEHVEVSKRSKEDLFVN---E
DVYEHYSQSSRVTRFGKSKHKQSALNQTQST-GLRK------------------GRKNTQ
DKRTQSDD-GD---CTSRQAITVSSPRKINRLVTHQQHILQTLDGLQEECYEPCSPTVSS
L---KDGLGNKVKVCSVSKEVH-----------------T------QEGQEMQFLGLEHI
GQTEAGSFSGPSLHKEVRLPLVSTDQQLHGYQEQ-QNSPYKSHDNSNLGKKIKT-FNKWE
SSFLSFIKDSY---------DDCCVSEKPVTSGMAICSAECKNHS--EENLRNTEERNFQ
RLLPSED-HFSQENELKEGGITMLPQQEAVSFSDLVEVVISEQPVANYEQCMDGTYFDQS
LGNPKQTSLTCKRTL-SIHEVSKLTSHVELLKKPQDY-NPRESTPLMSQTDTHIMEKVM-
---KEDTERHYSDKDEK----ARLFSTVVHSQEIEITNVERKRQDLSESEPMTNTNVCST
NNINKELTDVSGC--NQKEKEIS------------------------HKPGEELTSAINE
SESIVTNCLDKKEKVDSEIYMSLNAQEHKKYQ-NFK-KRKGLLKATCNQGL---------
------------------------------------YSSL--CKNFVKKGESKNSFF---
----F---------CFFLFSFLGWT--PLKE-----FSDVTVELLKAGADVNCESIDGIL
PLDDAAAGNHLKVAEILLQHRANPNPKDKTQKTPLHEANNEKMKELLKSYGTTETSNKDD
-------IKSPA--VHSKRYKR---CLCDDDKT-VDPSSSSQ--QEKGIEDFPLHQTISA
ILQDVEENQEKLLEFEIRNPKDAEQYIEKMLEIKEILDNVLAKQKAERDD---LAKKY-R
VSIESFKHGVLREQLANLATRQRRLLVAAKKQKNISLKIQNYKNVTSLSIPHLRKLPSSL
DTSSDKDSQ-ELSSLENLVKPQLS-----PCSSVNLDCESV-----------QGTLLSPE
SWDDSQNAS-ICLNS-----KAVRRKEFSGNEMNSKQNEN------------DCTLNGLS
KSRYSDSTE-IKLSSQHVTFIAQAEYSQK--EN-DPPETVAKNHEF--C-GP-SATGTLN
ISECSSILSQNDTPLSTVISHQDLSHCDSK-RGNKT------AGGASESL-----PHQSS
A-V-LG-TDTGHPIKPCLK-KTASTISCANDRQISSSSESGHQH-SMKKPLSFSTTPKKK
LMHIKDLILLGRIKPGNDVLEFRTQEATHKASILLSGKIKVENGQIYQNPVTWLKDLLGG
DSRVTWNYAWSKVTYLGKELLKYISEEIPVPPEPDVVPQQHQPCLPG-------------
--------------ISRESRESIPYYLQ-INEILLISDQEFLPCHLMDQHWKFFVECLFS
------

------------------------------------------------------------
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-------------------------------------NTLHNIHKRNH

PF00023 // ENSGT00760000119090_5_Domain_2 (1429, 1461)

MGETQLHLSAKK
GDLASLRILLKAGVNVNQKD

ENSGT00760000119090_5_Linker_2_3 (1461, 1462)

N

PF00023 // ENSGT00760000119090_5_Domain_3 (1462, 1496)

AGWT--AMHEASCKGFTDIIVELLHAGADVNSKS

ENSGT00760000119090_5_Linker_3_4 (1496, 1497)

L

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1529)

DGIL
PIHDAVMGNHYKAAKLLLEFGADPFEKDENQENAFDKSCSKGMTQLLISYSRTLQTASQE
NVSEISGWAIDGKLIVQSWYSWT--AWCPTSKKKSCPPVPFHAHPPLTSTSLMSPMPTSY
LLEDTNNRQGKLLLKEILTPLDADKYQETC-LVKANLNDVVKMQKNEREI---LAKRYRR
ASVDSFKQGILREKIAELAARQNILQQVVCQQKEVSQKIAAHKQSKKSDAYRLEQSSFL-
HSCNMSPGR-------NQM-PAVWSV--SAGLDASIANGSTEATVV------PAISGSPD
LE---NNTL-QEILM-----RSIGIGDIPANVVTAKESTANGKRLKEKSLEIENAFLDLG
SS----------FSSSPSTL-------QN-VTNEHL----AFTNTLCMSTNPVPVTSTLI
IKETGKTMVQNTNPVRHS--------------------YQMPHTEHSHTHHADMVSHQKE
KMSWFSVNNLTSVGKPHHGMVDQASTSHVASVQSNPVQRSESLS-TAKSHTGRAIRQRPN
KVHIKDLIKNGKLKPGEDVLEFKIQEYSHKASLLPDGTIKDSTGMIYLELAHWLKAILGN
NISISWKYIINKVTYCGKDLKSCILQKDPMSREFLQPTSDSQAAG-KYKFMSQYS---VN
PSKQFFQLTALP--SMSSSIQKEPLHVFRIKDILIFDNDEFLPCHIMDRYWKKFIDSDSL
DL----

MEEGVQDPDWDSDETVIEGSVTESDLEEKELRWRRLLFDQDTALKSEFSLHPDTRGMCEV
-GKNCF-----------------------------FSWQS-QDET--ERNQALLQTRKNC
SMFIGSFHQSGLSLNH-----------QNSEGPEADETP-----EV---LPHIEKELSDG
RDSPEVSLLSGTAITVSDMVAIKETSLIEPEKILAAPNTFFEPRK-EVILTVTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------FELVSDFDRKELMDPLSDSLS
SISI-PLNAWSACH-----RDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EVKFNTSQ-TNEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCEPLSNKRNSHSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGREDLTNNNSSAQNFRMQDPALMIDSKEK----NMHSRR
------FKNGK-QIRKNEQFPG---KKEKMKVNKISLGSINRRNIFGENLVYKAALNDDA
DLVHHCIKKGGNVNQPSYA---

PF00023 // ENSGT00760000119090_5_Domain_0 (623, 652)

GWTALHEASVGGFYRTASELLKGGADVNIKGMYQITPL
HDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEHYQKDPQNTKFGKSKHKQSTVNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCILETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKETH-----------------I-QNLDLSDSQEVQCLELESI
DQTEAVSFPGLSLHKEITLPLVTTDKQPHTLQEQ-HHVLYKSYENSNLVQKDER-FNKWE
NSFLSFVKGNSDND-----DDDCCTSEKAITSKKVMCSIGCKKHCNFKENLTNRREKDFQ
QFLVSED-HFSQENELQAVSLTTLPEQEAVNFSHSDNAVISE-HVANYEQCIFGPSFDHS
HNT-------------STHEVSQLTNHVELFKKPQDY-IPREPTFLMN------------
--------KNYTDRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPDEELTDNISG
DGITIRNFEEIKEKTKAEMHMPANSQEHKTVQ-NFG-KKQSFLKTTCNL-----------
----------------------------------------CGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARK
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKVNCANIDGTL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLKSYGAIETDNRDE
RDAIV-NEKIPA--VQSKRHKQ---CFCDDGKT-IDSPFLSH--QERSSESLSVHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLNIKEIMDNVLAKQKAERDD---LAKKY-R
ISIESFKHGALREQLANLVARQKSLLVVAKNQKRISLKIQNYKNVTSLPCLSLRKLPPRS
ENCSEKDNQ-ELTSLENLEHPQSG-----LLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDVNSKQNVS------------DCTLDGFP
KSQHSDGTENNKLPSQPVAFIGQTEYSQKEKEN-DLIEATDKDHEF--C-IPSPVIGKLN
ISETASVLAENSAHPSNIICDQDLSNYHPK-RGNRKTTSRQSPTGASESL-----AHQGV
A-V-LG-SDTVHPMKPYRK-KSVSAVPRADDSQISSSSGSGQQD-IIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQEATHKASILLNGKLKVESGQIYKSPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSGPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFGQGTSREPMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFYVGCEEL
TL----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MDKISLSRINRRNIFGENL

PF12796 // ENSGT00760000119090_5_Domain_0 (591, 678)

LYQAALHNDV
DLIHRYITKGGNVNQPSYA---GWTALHEASVGGFYQAASELLKGGAHVNIKGMYQITPL
HDAVINGHYKVCDAFVCKANTKFY------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------

MEEGVQAPDWDSDETVIEGSVTECDLEEEELPWRRLLFDQDTSLRSEFSLHPDTRGMCKG
-MPSPEIQLGFKI--RKDLQEQMNKNKVMPVPSKDIILQS-QDET--VQNQAPLQTRKNC
SMFIGSFPQSGLSSNH-----------KNIEGPEP-ESP-----EV---LPHMEKELSEG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAEPNTFFEPRK-EVTLTMTSEETKDE
ENSLETFVSALERLLTSPESAQEERL-------------FELASDFDPKELMNPLSDSLS
SISI-HLNAWSSCH-----RDLQENVK-DDALPAELLE-ALNTLSEAKVETICHRKEGGS
SLSAR----NEC--L------------EVEFNISQ-TSEDRTQIA-----ETLQDSNPSG
LQTLAHQNMTSCEPLSNNRNSNSVTN----SSDQETACVLRRSSR--LEKLKISRDA--K
YSDHMYK----MPEKILPKIIGYEDLTDNNSSTQNFRLQDPALMTDGKEK----NMHSAR
------FKSGE-QIRKNEQFSG---RKEKMKVKKILLSSINRRNSFGENLVYQAALHDDA
DLVRHYIKQGGNVNQLSYA---GWTALHEASVGGFYWTASELVKGGADVNIRGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVMNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDS-CMKRLLERYIPKHQKCLTLA
QRNSTDPLDTEDIYQHKKPKFSSKSHICHVCNENCNRQKQDHVKVNKERKESLFININKE
DVYEYYQKDSRNTKFGKSKHKRSTLNQIYST-GPRKRSIYNVKDSNTNV-PKGIGRRNTQ
HKRTQVDD-VD---CNPRKALAVSPSRRINRLVTDQQHIPQTFSDLPEESCQPSSITLPS
L---KNGLGNNIEVCSVSKETH-----------------I-QNLDLSDSQEVQCLD-ESV
DQTEDVSFPGLSLHKETKLPLVTTDKQPHTLREQ-HRILYKSHENSKLVQKDQS-FNKWE
KAFLSFVKGNSVND-----DDDFSTSEKAILSKKVTCSTGCKNHYNFKENLTNRKEMDFQ
QFLLSED-HFSQENEVKSVSLTTLPEQEAVNFSDSDNIVISEQHVANCEQGIFGPSFDHS
HGNPEQNSLVCMRTL-STQEVSKLTNHVELFKKPQDC-IPRAPTFLMNQTDTHIVEEVA-
--KNCDTERNYIDRDQKLSYSNEPLLRVVHSQVIETTKAEKRRQN-LESETMCDTDSHST
DDMNKDLANISQL-SQREKKEIS------------------------HKPDEELTNNISG
DEITTRNCEEIKEKTESEIHMPTNIQEHETVQ-NFR-KRQSFLKTTRK-GM---------
------------------------------------K--TGGINKRNARGKSR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLVKALIESGADVNLNDNAGWT--PLHEASSKGSIDIIVELLKAGANVNCENIDGIL
PLHDAVANSHLKAAEILLQNGANPNQKDKKQKSALDGADDEKMKELLKSYGAIQTNNRDE
SDGIV-NEKIPA--VRSKRHKQ---CFCDDGKP-VDSPSLSY--QERPRESLSAHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLEIKEIMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLASLATRQKSLLAVAKKQKKISLKIQNYKNVASLSCPNLRKLPPRS
EIFSEKDSQ-ELTSLENLEHPQSV-----SLSP---VCGSM-----------QETQLSLE
TWNYSQNNN-ICLNS-----EAVIRGEFSGNEMNSKQNIS------------DCTLDGLS
KSRHSDGTEKIKLSSQPVAFIGQTEYSQK--ET-DLIEATDKDHEF--C-SPSPIIGKLN
ISETASILAKSDAHPSNVICDQDLSNYDPK-RGSRKTTSQEPPRGTSESL-----AHQGI
A-A-LG-SDTVNRMKPYPK-KSVSAVPHADDSQISSSSRSGQQY-TIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGRIYKNPVTWLKDLLGG
NSYVTWNYAWNKVTYLGKELLKYVSEDISILPEPNSVPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFEQGTSREPMQSIPRYLQ-INEILLISDQEFLPCHIMDQHWKFCVECEEL
TL----

MEEGVQDPDWDSDETVIEGSVTESDLEEKELRWRRLLFDQDTALKSEFSLHPDTRGMCEG
-MPSPEIQLGFKL--KEDLQEQMSKNRMMPILSEDTILQS-QDET--ERNQALLQTRKDC
SMFIGSFHQSGLSLNH-----------QNSEGPEADETP-----EV---LPHIEKELSDG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAAPNTFFEPRK-EVILTVTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------FELVSDFDRKELMDPLSDSLS
SISI-PLNAWSACH-----SDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EVKFNTSQ-TNEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCEPLSNKRNSHSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYR----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDSKEK----NMHSRR
------FKNGK-QIRKNEQFPG---KKEKMKVNKISLGSINRRNIFGENLVYKAALNDNA
DLVHHCIKKGGNVNQPSYA---GWTALHEASVGGFYRTASELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVMNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEHYQKDPQNTKFGKSKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCILETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKETD-----------------I-QNLDLSDSQEVQCLELESI
DQTEAVSFPGLSLHKEITLPLVTTDKQPHTLQEQ-HHVLYKSFENSNLVQKDER-FDKWE
NSFLSFVKGNSDND-----DDDCYTSEKAITSKTVMCSTGCKKHCNFKENLTNRREKDFQ
QFLVSED-HFSQENELQAVSLTTLPEQEAVNFSHSDNAVISE-HVANYEQCIFGPSFDHS
HGNPEQNSLACMRTL-STHEVSQLTNHVELFKKPQDY-IPREPTFLMKQADTHIVEEVA-
--KNCDTERNYTDRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPGM--------
-----------------------------------------------KT-----------
----------------------------------------GGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARK
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIILELLKAGAKVNCANIDGTL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLKSYGAIETDNRDE
RDAIV-SEKIPA--VQSKRHKQ---CFCDDGKT-IDSPFLSH--QERSSESLSVHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLNIKEIMDNVLAKQKAERDD---LAKKY-R
ISIESFKHGALREQLANLVARQKSLLVVAKKQKRISLKIQNYKNVTSLPCLSLRKLPPRS
ENCSEKDNQ-ELTSLENLEHPQSG-----LLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDVNSKQNVS------------DCTLDGFP
KSQHSDGTENNKLPSQPVAFIGQTEYSQKEKEN-DLTEATDKDHEF--C-IPSPVIGKLN
ISETASVLAENSAHPSNIICDQDLSNYHPK-RGNRKTTSQQSPTGASESL-----AHQGV
A-V-LG-SDTVHPMKPYRK-KSVSAVPRADDSQISSSSGSGQQD-IIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKSPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFGQGTSREPMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFYVGCEEL
TL----

------------------------------------------------------------
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--------------------------------------TVTRVCKRNAK

PF00023 // ENSGT00760000119090_5_Domain_2 (1430, 1461)

GKSRLHLAAKR
GDLSLVIALIESGAHLNQKD

ENSGT00760000119090_5_Linker_2_3 (1461, 1463)

NA

PF00023 // ENSGT00760000119090_5_Domain_3 (1463, 1493)

GWT--ALHEAADKGFNEVMVELLKAGANVN

ENSGT00760000119090_5_Linker_3_4 (1493, 1497)

SESL

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1528)

DGLL
PIHNAVSGNHLKAAELLLQHGANPNQKDGDQKSALDRAKDEKMKKLLKSWSGNETRNICH
NKVTV-IEKINL--QMSKRQKQ---ESCCKSKS-AGPLSFSH--QDSTKEGAPMHDSIHT
ILQDIGEKQESLLLFEIRTPKDADQYSEKMLQIKDIMDSVLAKQKKERDD---LAKKY-R
SSIESFRQGALREKLANLATRQKNLLIVAQKQKKLSQKIQNYKNTRNTSGLGARQESPDL
RNSNENDEGSYFIPAEKATQPDSVSVPVRFPSSPTSGSSQRTHCT--RR---QE------
---DNQNLS-SCISERWVHEKTAESECFSFNELITNERPG------------DYTLKRTS
KSNYIRGIKMVKLPPQSVTSSAQAEYLEE--KN-YTAVITAKGSKS--L-NPSAITETLN
ILETPSATVRNNTHQLNTVCQPAFTHSLLPGNTSKKTVSQDPPGTVSESLVQSLLAHQGN
AC--AD-SGALLRMKPNHT-ESRPVGTLADNSQINFSLESSNQN-NKQEPLHCRAEMKMK
KTQIKELISLGRIKPGNDVLEFKMQDATYKASILQNGKIKAKNGEIYQNPITWIKALLGS
NISVTWKYVWNKVTYLGKELCKYITEEVPIITEPNVVLQENQPCMPVICILDLT----KE
NSQNCFDKQKEGRGRSSGSVQNFKHYLQ-LNEILLISNQEFLPCHIMEQHWKFYMASENG
LF----

MEEDAQAPDWDSDETVIEGSVAESDKEDEELPWTRLLFDQDKSLTSEFYLQPGISAMCKG
-TPSPEIQLGCKL--REDSQEQINKSKMMPILSEDSGLQV------------CSMTRKNF
AMSPVSFPQAGFSLNQ-----------QNIGGKC---------------------ELSED
RDSPEISLLSNIATTVSGMVAVEEKSLIETEKISAAPKKSYHPGK-EVTLTMISKETNNE
ESSLETFVSALEKLLRSPESTQEKRL-------------FKTMNDFDTGELMNALSNSSS
SMSV-SLSALSPYC-----RDLLENAE-DDALPPELLA-ALNTLSEDKTELICHRKKEGG
SLRGR----NEY----------------LEPDSSQ-TNEDCTQIT-----EV--------
----------------------------------KTPCVLRRSSR--LEELKISRDA--E
CTDDMYK----MPEKIVPKMHSCEDQINNKS-IENFRYN------------------ISR
------FKGK--QIRKNERLI---------------------------------------
----------------LKK---GWTALHEASVGGFYRTANELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 682)

ITPL
HDAVVNGHHKVAELLLLSGAD

ENSGT00760000119090_5_Linker_1_3 (682, 1434)

PLFRSDNGKCALDEAKDS-RMKRLLEKYVPQCQKHLTSD
QRKRIDTRDVEDVHQHKKTKFSPKNRTGFVCNENSNRQKPEHVEVNKRSKEGFFIN---E
DIYECYPQNSKITRFGKSKH-------------------------NTNV-SEGKGRKNTQ
DKRTQAND-GD---CTSRQAIAISSSKRINTLVTCQQHILQTLDDLSEESHEPSSPTLSS
L---KDGLVNSVAICSVSKEAH-----------------T-RHLDLSEGQEMQFFGLEYI
GQTESGSFSTPSLHKEVKLPLVSTD-QPHVYQEQ-QCSPYISHKNSNSGKKVKT-FNKWE
NSFLSFVKEHSYNY-----NGDFCIAETAITSEMVTCSTECKNYYQ--ENLRNREERDFQ
QLLPSED-HFLQESELKESSLTTFPQQEAVNISNSDKAVISEQHVANYEQCIYGTSFDHS
FGNREQTSLACTRTV-STHEVSKLTSHVEKLKKPQDN-SPRESTPLVNQIDTHIMEKVYV
ELK-EETERNSSDKGQK----PRLFPTVVHSQKIEIINVEKNNEYLPENELIPNKNFCST
KNMNKELTNISEF--NQQEKEIS------------------------HKPDEELPNIIIE
DENIVRNCEEKKEKIDSEIYIPTNTQEYRKDQ-NFG-KRQSFSKATCNQGL---------
---------------------------------------CSCLGKRNARGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHSAARR
GDLSLVQILIESGADVNLKDNAGWT--PLHEASNEGFSDIIVELLKAGANVNCESIHGIL
PLHKAVASNHLKAAEILLQHGANPNQEDQTQKTALDEADNEKMKELLKSYGAIETNNRDE
-------IKSPT--VWSKRYKQ---CLGVEDET-VDPPTPSH--QEERRENFPVHQTISA
ILQDIEENQETLLEFEIRNSKDAEQYIKRMLEIKEIMDNVLSKQKAERDD---LAKKY-R
VSVESFKHGVLREQLANLATRQKKLLVAAKKQKNISLKIQNYKNVTSLSGLPSRKLSSSL
DISSDKESQ-ELTRLENVVQPQLS-----PFSAVNLDCGSV-----------GETPLSPE
TWNDGQNTN-ICLNS----------KKFSRSEMNLKQNES------------DCTLDGFS
NSIHSDTTEKIKLSSQQATFIAQTEHSQK--EN-DLIEMIAKDHEF--C-SPSATTSSLN
ISECTSSLSQNDPYLSTVISDQDLYHCDPK-RRNKKTASQLPPGGVSESV-----AHQRS
A-V-LG-TYTGHALKPCLK-KAASAIPRANDRQISSSFESSHQH-TIKNPSSFSTTPKKK
CMEIKDLMLLGRINPGNNILEFRTQETTHKASILMSGKIKVENGQIYQNPVTWLKDLLGG
DSYVTWNYAWSK------------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
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-----LFLNIK-TILHQKPKFSSKNHSGFVCDENSNRQKPEHVEVNKESRKSLFIN--TD
-IYERYQKDSPNMRIGKSKQKQSVLNQAHSI-GFRKDNLRSAEDPSTSV-SKDKGRRNAQ
HKRTQVDD-TSQE-SSPRKTVAVSSSRRRSRSVTRQQQALQILDDLPEKSCKPFSQALSG
L---KNGLCNDVETCSILRETH-----------------T-QSLDLSDSQEIQCMEVEST
DQAEAVSLLGLSLHEKTKLIPVTTDQQPHTLHDQEHVSPYKSHENSNSSQKDE--SLKWE
KISPSFIKENFNND----DHGDSCASEETVISKKVISSSGGKNHDNCKENKTNREEMDFQ
QFLPSQD-HFPQENELKADSLTILPQQEAVRFSNSDDIIV-SEHVPDYEQCLYGTSFDHS
HGSPEHTPLACIGTL-STQEASELTSHEKLIKNPQDY-SPSTLTPLMNQTDRHIVEKVN-
--REGDTKRNYTDTGRETSPSNRPSSRGVPSQVMETTEVEKRRQE---SKAIQNTGFHST
DN--EELSNISQL-SQREEREIS------------------------HKPGEEFV---NG
DENGVRNCKEKKEKPDSEIHMPTNIQSHKKIQ-NFR-KRKTVSKATCSQER---------
------------------------------------K--TSGIDERNAT

PF00023 // ENSGT00760000119090_5_Domain_2 (1430, 1461)

GESRLHLAARR
GHLSLVKALIESGADVNLKDNAGWT--PLHKAASNEWSDV--ELLKASANVNCENV

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1528)

DGIL
PLHDAVANNHLKAAEMQLQHGANPNQKDEKQKTALDEADDENMKELLKSYGAVETDSRDE
SDAVV-TVKTPD--VRARRRKQ---CICDDSKT-VDRPSISH--QDKTEENLSMHQTISA
ILQDIEEKQENLLEFEIRTPEDAEQYAGKMLEIKEVMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGVLREQLANLAARQKSLLLVAKKQKKISQKFHTYKNATSLSGLSFRKLPSSS
ETSNEKDRQ-ECISMENSMQPQSG-----SLSPVSLVCKGT-----------QETQLSQE
VWHDNQRTH-TCLNS-----KTVRREEFSGSELNSKQNTN------------DCTLDRLS
NSRHSDGTNQIKLQSQSVTFIAEAEYSPK--EN-DLTGSTAEGHVS--F-SPSAVTGTLK
ISATTSVSAHHDAHPSSVICDQGPSDCDPK-EGNRKTAPHRAPGGTSESL-----AQQGV
D-V-FG-SDMGQPLKPYLK-KSALTVPHANNTQSSSSSGSGYQH-TVKKPSNYNTTAKKK
CLQIKDLILLGRLNPGNNILEFKTQEATHKASVLLSGKIKVENGQIYQNPVTWLKDILGG
DSYVTWNYAWSKITYQGKELLKYVSEELPMPPDPNLVPQQHQPHLPGT------------
---------------SKESMQSIPHYLQ-IKEILLSSDQEFLPCHIMDEHWKFYAECEEL
TF----

MEGGDQATDWDSDETVIEGSVTESDPEDEELPWRXXXXXXXXXXXSVYKFHPGISTTWKG
-TTSPEIQLAFKL--REDPQKQLSANK-LPLHNEDKILQXXXXXX---XXXXXXXTRQNC
SRLTESYPQAELLLSH-----------QSMKESGAD--------DYPEISTYPEKELSED
RDSAEISLLSGTFLTVSDTALVKDKLLIEPEKMLIGSHIFSEPGM-EVTLEMTSEE-KSE
ENSLETFVSALE-------ITEEDRL-------------LEIMSDFEPTELINPLSKSAN
SISI-PLT----CH-----RDLLEHTN-DNALPTELLSSSLNPKSESQVDPICHRVEEGN
SVSAE----SKR--L------------GVERTLSQ-TNEDSTHIA-----EPTEDQNPFE
LQTLVHQNVTFCDPLNNEGNSNPLDV----NSDQDTPIVLRRSSRLKIG-----RQE--Q
HRDERCT----MSEKILPEMVDREDQTSRDSSNENSGXXXXXXXXXXXXXXXXXXXXXXX
------XXXX--XXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX---XWTALHEACVGGFYQTASELIKGGADVNIKGM

PF00023 // ENSGT00760000119090_5_Domain_1 (655, 687)

YQITPL
HDAVVNGHYKVAELLLLNGADPLLRSDSGKCALDEAKGS-RVKRLLERYVSKHQKPLRSA
QKNSVDLVDVEDTHQHKKPKYSSRKCTGFTFEENSNRKKPEHINLGRESKEYLRIN--KE
DVYEHHQKRSANIRLGKSKHKELILNQTKSR-GLRKDNLPYVKDSSSDIS----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

MEEGAQAPDWDSDETVIEGSVTENDLEEEELPWRRLLFDEDTSLRSAFSMHPDISGICKG
-MPSPEIQPGFTL--REDLQEQTNKNKMMCVLSEDTILQP-QDET--EQDKPLLQTRKNY
PMFTVSFPQAGLSLNH-----------QNTGGPEA---------EDSEVLSHLEKNLSED
GDSPEVSLISGTSVTVSEVVAIKEKSLIAPEKILAAPNTFSEPGK-EITLTMTSEEIKDE
ENSLETFVSALERLLTSPESTQEERL-------------FEIINDFDHIELMNPLSSSPS
SISI-PVNALSACH-----RDLLENTK-DDALPAELLA-SLNTLSEAKMKPICHRKEGGS
IVNAG----NEY--L------------EVEFNMSQ-TSEDGTQI-------TLEDPDSFG
LQTLAHQNVTSCKPLNNKENSNLVEN----SSDRKTARVLRRSSR--LEQLKVNRDV--K
HTDDMYK----MPEKILRKILSCENQTNNNSSTENFRMQDPASMIKAKGK----NMHSSR
------VKSGE-RIRKNKILTG---KNGEAYFE---------------------YFSIYV

PF12796 // ENSGT00760000119090_5_Domain_0 (601, 682)

DLVRHCIKKGGNVNQPSYA---GWTALHEASVGGFYETASELLKGGADVNIKGMYQITPL
HDAVINGHYKVTELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFRSDSGQCALDEAKDS-HMKRLLERYVPKDQKYLTSA
QRNNTNPLDVEDVHQRKKPKFSSKNRIWFVCNENSRRQKPEHIKVNKGNKKDLFIN--KE
DVYECYQKDSKNTKFCKSKHKQSSVNQIYST-RLRKGSLRNIKDPSTKL-SKGKGRRNTL
YKMTQVDD-RD---SNPRKALAVSSSRRINRLVTRQQHILQTIDDLPEEACEHSSPTLSS
L---KNELDNNIEACSISKETQ-----------------I-QSMDLSDSQEAQCLELESI
DQTEADSLPGLSLHKEIKLPIVTTDQQPHTPQEQ-HSSPYKSQENSNSVKKDESIINKWE
KSFLSFIKRNVDD-----DGGDCSSSEKSVTFEKVICSTDYKNHCNDKENITNREEMTFQ
QFSPSEG-HFSQENELNAGSLTTLPQQEAVNFSDSDNVVISEQHVMNFEQCIYGTSFDHS
NSNPKQTSLAYMKTL-STHEVSKLTSHVDLFKKHQDY-SPRAPTPLMNQTDIHIVEKVT-
--KKQDTKRNYTDKGQKTSSLNGPLSTVVDSQVIETTEVEKRRQNLPENRTIHNIDFHSA
DNMNKELTNITQL-GQREEEETS------------------------HQPVEELTNNVNG
DESTMRNCKEKK-KTEPEIHIPTNTQEHKKVQ-NFR-KRRNFLKATYSQGM---------
------------------------------------K--TAGINKRNAKGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LYLATRR
GNLSMVKALIESGADVNLKDNAGWT--PLHEAATEGSADIIVELLKAGANVNSESQDGIL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKTALDEADDEKMKELLKSYGAIETNNTEE
SNVII-NEKIPA--VRLKRHKQ---CFCDDGKP-VHPPSFSH--QGETRENLPVHQTLSA
ILQDIEEKQENLLAFEIKNPEDAEQYIEKMLKIKEIMDNVLGKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLATRQKSLLVAAKKQKEISLKIQNYKNVTSLSGLGLRKLPPSS
ETSSEKDSQ-ELNSLENSVQPQSG-----SFSPVSFVSGSM-----------QDAQFSIE
TYNYSHNTN-ICLNS-----ETVRREEFYGNEINSKQNVH------------DSTLDGLS
TSRHSGD-TEIKLPSQPVAFIPETEYSQK--EN-DLIETTAKRHEF--C-SSSAVTGTLN
ISETMSVFAQNDAHRSTIIRNQDLSN-VPK-RGNRKTASQQPPWGASKSL-----ARQGI
A-V-SG-SDTVHEMKTCLK-KLASTVPHVNDSQNSSSSGSGHQH-TIKKPLNYSTAPKKK
CMQIKDLILMGRINPGNNILEFRTQDTTYKASILISGKIKVENGQIYQNPVTWLKDLLGG
ESYVTWNYAWSKVTYLGKELLKYVSEEVPILPEPNLVSQQHQTCLPEAPCL-DDPV--QE
PSKLVFEKTKFGQGTSRKSMQTIPQYLQ-INEILLFSDQEFLPCQIMDQHWKFYVECEEL
TF----

MEEGVQAPDWDSDETMIEGSVTESDLEEEELPWRRLLFDQDTSLRSEFSLHPDTRGMCKG
-MPSPEIQLGFKI--RKDLQEQMTENKVMPVLSKDTILQS-QDET--VQNQALLQTRKNC
SMFIGSFPQSGLSSNH-----------QNIEGPEP-ESP-----EV---LPHMEKELSEG
RYSPEVSLLSGTAITVSDTVAIKETSLIEPEKILAEPNTLFEPRK-EVTLTVTAEETKDE
ESSLETFVSALERLLTSPESAQEERL-------------FELVSDFDPKELMNPLSDSLS
SISI-HLNAWTSCH-----RDLQENVK-DDVLPAELLE-ALNTLSEAKVETICHRKEGGS
SLSAR----NEC--L------------EVEFNMSQ-TNEDCTQIA-----ETLQDPNPSG
LQTLAHQNITSCEPLSNNRNSNSVTN----SSDQETACVLRRSSR--LEKLKINKDA--K
YSDRIYK----MPEKILPKILGCEDLTDNKSSTQNFRLQDPALMTDGKGK----NMHSAR
------FKSGQ-PIRKNEQFSG---RKEKMKVKKILLASINRRNIFGENLVYQAALHDDA
DLVRHYIKQGGNVNQPSYA---GWTALHEASVGGFYWTASELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVLNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDS-CMKRLLERYIPKHQKCLTLA
QRNSIDPLDIEDVYQHKKPKFSSKSHICHICNENCNRQKQEHVKVNKESKDSLFININKE
DVYEYYQKDSKNTKFGKSKHKQSTVNQIRST-GLRKCSIYNIKDSNTNM-PKGIARRNTQ
HKRTQVDD-VD---CNPRKTLAVSPSRRINSLVTYQQHIPPTLSDLPEESREPSGITLPS
V---KNGLDNNIEVCSVSKETH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLSLHKEIKLRLVTMDKQPHTPREQ-HRILHKSHENSKLVQKDES-FNKWE
KAFLSFVKGNSDND-----DDDFSTSEKAVISKKATCSTGNKNHYNFKENLTNRKEMDFQ
QFVLSED-HFSQENEVKAVSLTTLPEQEAVNFSDSDNVLISEQRVANCEQCIFGPSFDHS
HGNPEQNSLACMRTL-STQDVSKLTNHVELLKKPQDC-IARAPTFLVNQTDTHIVEEVA-
--KNCDTERNYIYRDQKLSYSNEPLSIVVHSQAIETTKAEKRRQN-LESETICDIDSHST
DNMNKDLANISQL-SQREKKEIS------------------------HKPDEELTNNITG
NEITTRNCEERKEKMESEIHMPTNIQEHKTVQ-NFR-KRQSFLKTTCK-GM---------
------------------------------------K--TGGINKTNARGKSR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLVKALIETGADVNLNDNAGWT--PLHEASSKGSINIIVELLKAGANVNCENIDGIL
PLHDAVANNHLKAAEILLQNGANPNQKDKKQKSALDEADDEKMKDLLKSYGAIQTNNRDK
SDGIV-NEKIPA--VRSKRHKQ---CFCDDGKP-VDSPSLSY--QERSRERLSAHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLKIKELMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLATRQKSLLAVAKKQKKISLKIQNYKNVTSLSCLSLRKLPPRS
EIFSEKDSQ-ELTSLENLEHPQSV-----SLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVIRGEFSGNEMISKQNIS------------DCTLDGLS
KSRHSDGTE-IKFSSQPVAFIGQTEYSQK--EN-DLIEATDKDHEF--C-SPSLVIGKLN
ISETASILAKSDAHPSNVICDQDLSNYDPK-RGNRKTTSQKPPRGTSESL-----AHQGI
A-A-LG-SDTVNQMKPYLK-KSVSAVPHADDSQISSSSRSGQRY-TIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGG
NRYVTWNYAWNKVTYLGKELLKYVSEDVSILPEPNSVPQQYQHCLPEVACLDDPV---QE
PSKSTFEKTKFEQGTSGEPMQSIPRYLQ-INEILLISDQEFLPCHIMDQHWKFCVECEEL
TL----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MFLNIKNIILHQKPKFSSKNLIGFVRDENSNRQKSEHVEVDKGSKEGLFIN--KE
VVYEHYQKDSKDTKFGKFKHRQSTFNEIHSTRRLRKKGLQNIKGVNTSM-SKDKGRRNTG
QKRTQVDD-PKQEICIPRKARAVSSSRRINRLVTGQPDTLQAFDDLPEKSHKLFSPALSS
L---KNGLGNNIEACLVPKETH-----------------I-QSLDLSDNQEMKFLG--ST
DQEEAVLFSRLSLQKEIKLPLVTTDQQPHTHQEQQHISPYKSPENSNPGKKCEN-LSKWE
NSFVSFIKENFNNV----DDDDCFTSEKTVTCKTVVCSTGCKSHCNYKENVTTRKEMDFQ
QFVPSED-HFSQENELKVCSLTI--QQEAVNLSDSDNTIGPEQRVAIYEQCKCKTSFDHS
HGNSEHTSLACPRTF-STQEASKLTSHVKLFKRPQDF-SSRAPTPLIDQTDIHIVEKVN-
--EREDPKKNCNDGSRKTSSSNGPLSTVVNSQVIETTAVEKRKQDLPKSKTIHDTVFYST
DNISKELTNISQL-RQKEEKEIS------------------------HKADEELTSNING
DESTMRN-GEKEEKTDSEIHMS-NIQECKKVQ-NFRK-RQNLLKATRSQEM---------
------------------------------------K--T

PF12796 // ENSGT00760000119090_5_Domain_2 (1421, 1494)

AGINKRRARGESRLHLAARR
GTLSLVKAPIESGADVNLKDNAGWT--PLHKASTKRSNDKIVELLKAGANVNCEKLGGILPLHDAVANNHLKAAEILLPHGANPNQKNQKQKTALDEADNEKMKELLISFGAIETDNRNESNATV-TVKIPA--VQPKRHKW---CFCDDCNT-VDPPSLSQ--REKRRESYPVHQAISAILQNIEEKQGNLLEFEIRTPEDAEQCIEKMLEIKEIMDYVLAKQKAERDD---LAKKY-RVSIESFKQGVLREQLANLATRQKSLLVVAKKQKKITEKIQNYKNITSLSGPSLRKPPSSSEISSEKDSQ-DLISLENSLQPQSG-----SLSLVSLTCGSM-----------QETPLSPETWNSSPNTN-TCVNS-----ETVRR-EFSGNELISKQNVN------------DGTFDGSPKSRCADGT-KIKLPSQPVALTAQREYSQR--GN-DLTEPPAPEREP--CNHPSAVTNTLNIAATTSILARNDAHPSAVVCDQAPTSCDPK-RGKRKIASQQPSRGTLESL-----THQGTD-V-LG-SNTGHQTKSYPK-KPAFTVRRANDSHSSSPSERGRQH-IIKKPVNSSTVPRKKCMQIKDLILLGRINPGKNILEFKTQETTHKASVLLSGKIKVENGQIYQNPVTWLKDLLGGNSYVTWNYAWSKVTYLGKELLQYVSEEVPVSAEPNVVLQQHQPCLL-------

PF12796 // ENSGT00760000119090_5_Domain_3 (1421, 1494)

AGINKRRARGESRLHLAARRGTLSLVKAPIESGADVNLKDNAGWT--PLHKASTKRSNDKIVELLKAGANVNC

ENSGT00760000119090_5_Linker_3_4 (1494, 1498)

EKLG

PF00023 // ENSGT00760000119090_5_Domain_4 (1498, 1528)

GIL
PLHDAVANNHLKAAEILLPHGANPNQKNQKQKTALDEADNEKMKELLISFGAIETDNRNE
SNATV-TVKIPA--VQPKRHKW---CFCDDCNT-VDPPSLSQ--REKRRESYPVHQAISA
ILQNIEEKQGNLLEFEIRTPEDAEQCIEKMLEIKEIMDYVLAKQKAERDD---LAKKY-R
VSIESFKQGVLREQLANLATRQKSLLVVAKKQKKITEKIQNYKNITSLSGPSLRKPPSSS
EISSEKDSQ-DLISLENSLQPQSG-----SLSLVSLTCGSM-----------QETPLSPE
TWNSSPNTN-TCVNS-----ETVRR-EFSGNELISKQNVN------------DGTFDGSP
KSRCADGT-KIKLPSQPVALTAQREYSQR--GN-DLTEPPAPEREP--CNHPSAVTNTLN
IAATTSILARNDAHPSAVVCDQAPTSCDPK-RGKRKIASQQPSRGTLESL-----THQGT
D-V-LG-SNTGHQTKSYPK-KPAFTVRRANDSHSSSPSERGRQH-IIKKPVNSSTVPRKK
CMQIKDLILLGRINPGKNILEFKTQETTHKASVLLSGKIKVENGQIYQNPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLQYVSEEVPVSAEPNVVLQQHQPCLL--------------
-------------GTSRESMQSIPPYLQ-INEVLLISDQEFLPCHIMDQHWKFYVECEEL
TF----

MEEGAR--DADSDETVIEGSVTESDQDDDELPWRSADL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------GRGSLQ-VHNGMGGMAEGG-IHSPEIQH
VLKLR----KNSEEQ------------KNKKEVMQ-T-LSEDTML-----QTVDDPKSFG
FHTLTHKNATSYKILNNNENSDPVKN----TSVKGTPCVRRRSSR--LEKLRVSRDK--K
HRDDTAK----VSERVLPKTLDCNSVL----------------ITKGKRN----SMYSSR
------LKSE--QIKKNEQLTIKNGETGEMKIYNMSLSNINRRNIFGENL

PF12796 // ENSGT00760000119090_5_Domain_0 (591, 682)

LYRAVLHNDA
DLVHHCIKNGGKVNQPSYA---GWTALHEASVGGFYRIVRELLKGGADVNIKGMYQITPL
HDAVINGHHKVAELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFRSDHGTCALDEAKDS-YMKNLLKKYVPKYKNCHVSA
RRKNTNPAYVEDVQQYKKPRYSSNNHTEFVHDKNSNRQNPRHVEINKGSKDLLTN---IE
GIYEHYQKDFRITKFHKKD------------------KLHSVRDNRTSV-SERKGRGNMQ
HRWTQVDD-RV---CSLSQEIAISSSRRMNTLATHEQHTLQTLDDLPEESCEFSTPTLSS
L---KNGFDGNNEACLASEESR-----------------T-HNLDLS----IQCLELESI
DQTKAASFSGLSLYKEIKFPVVTKDQQPPTNQEQ-CSNPCQFPENYSSDNKGKN-INEWE
NSFVLFIKGHVDND--------------------EIHSVEYTSHCNNEETRTNREEMDTL
QCSSSEM-CISRENDLKTGSPILLQQQKAISFCDSDNTFISEQHVANCEQYIYETSFDHS
HTNTDQTFLPCTRLP-LTHEISKLTSQVELLEKSQDN-APKEPTPLINQTDTDNVENK--
----QDNERNHTMKGQTPSSSNSPFPTVVHSQVTETTKVEKRREDLPENETMCNIDFHST
GSMKKKLANISQL-NQREEKEIY------------------------HKSGIAELTNTRK
NESAVRNCKEKKEKIDSEIHMPPNSQEHRKDQ-NFK-KSKKFLKAACSQVN---------
---------------------------------------TARIHKRNAKGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLASRR
GNLSLVKSLIESGADVNLKDNAGWT--PLHEASNKGFSDIILELLKSGAKVNSENVDGIL
PLHDAAVGNHLKAAEILLEHGANPNKKDQNQKTALDEADDEKMKELLKLYGAVESNNGDE
SNSTV-TVKIPD--IQPKRYKQ---CT-DDNKT-VDPPAPFH--QAKRSESLPVHQTISA
ILRDIEEKQDNLLEFEIRNPEDAEQYIGKMLEIKEVMDNILAQQKTERDD---LAKKY-R
VSMDSFKHGALREQLANLATRQKSLLVVAKKQKKIRSKIQNYKTATPFSSLSLRKLPCNS
DN-------RKLTSVENSVHSQSG-----SCSLINVADRSM-----------QEV-----
PWDDSQNTN-TCLNS-----ESARREEFSRNEVISKQNVQ------------HCTLGGLL
KSRHSNGPEKMKLSSQPVAFIDQVEYSQE--EN-VLTETMAKGHEF--D-SSPAVTSTIN
ISEDKSVFSQNDTCPATVTWDQDLSHCDPK-RRNKKRASQQPPGGLCEPL-----AQQGI
T-V-LA-TNTAHQAKPCLK-ETASSVSHAEGIQISSSSRSIHQH-SIKKPLNHNTAPKKK
SVQLKDLILLGRIKPGNNILEFKTQETTHKASILLSGKLKVESGQIYQSPVTWLKDLLGG
NSYVTWNYAWSKVSHSSIYL----------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------M---------
------------------------------------K--TSGIDKRNAT

PF00023 // ENSGT00760000119090_5_Domain_2 (1430, 1461)

GESRLHLAARR
GHLSLVKALIESGADVNLKD

ENSGT00760000119090_5_Linker_2_3 (1461, 1463)

NA

PF00023 // ENSGT00760000119090_5_Domain_3 (1463, 1495)

GWT--PLHKAASNGWSDVIVELLKASANVNCE

ENSGT00760000119090_5_Linker_3_4 (1495, 1497)

NV

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1528)

DGIL
PLHDAVANNHLKAAEILLQHGANPNQKDEKQKTALDEADDENMKELLKSYGAIETDNRDG
SDAVV-IVKIPD--VRARRHKQ---CICDDSKT-VDTPSISH--QEKTEENLSMHQTISA
ILQNIEEKQENLLEFEIRTPEDAEQYAAEMLEIKEVMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGVLREQLANLAARQKSLLLVAKKQKKISQKFHTYKNATSLSGLSFRKLPSSS
ETSNEKDRQ-ECISLENSMQPQSG-----PLSPVSLVCRGM-----------QETQSSQE
VWHDSQSTH-TCPNS-----ETVRREEFSGSEVNSKQNLH------------DCTLDRLS
KSRHSDGTNQIKVQSQSVTFIAEAEHSQK--DL-RGPGSTAKRHVS--F-SPSAVTGTLK
TSATTSVFAHHDAHPSSVICDQAPSDCDPK-EGNRKTAPHQAPGGTPESL-----AQQGV
G-A-FG-SDMGQQLKPYFK-KSALTVPHANDTQSSSFSGSGYQH-TVKKPSNYNTTLKKK
CMQIKDLILLGRLNPGNNILEFKTQEATHKASVLLSGKIKVENGQIYQNPVTWLKDLLGG
DRYVTWNYAWSKITYQGKELLKYVSEELPMPPDPNLEPQQHQPCLPGTDCLDSIVQSKYG
PSVKMFIESKGKTGTSKESMQSIPHYLQ-IKEILLSSDQEFLPCHIMDEHWKFYVECEEL
TF----

MEEDAQAPDWDSDETVIEGSVAESDKEDEELPWTRLLFDQDKSLTSEFYLQPGISAMCKG
-TPSPEIQLGCKL--REDSQEQINKSKMMPILSEDSGLQV------------CSMTRKNF
AMSPVSFPQAGFSLNQ-----------QNIGGKC---------------------ELSED
RDSPEISLLSNIATTVSGMVAVEEKSLIETEKISAAPKKSYHPGK-EVTLTMISKETNNE
ESSLETFVSALEKLLRSPESTQEKRL-------------FKTMNDFDTGELMNALSNSSS
SMSV-SLSALSPYC-----RDLLENAE-DDALPPELLA-ALNTLSEDKTELICHRKKEGG
SLRGR----NEY----------------LEPDSSQ-TNEDCTQIT-----EV--------
----------------------------------KTPCVLRRSSR--LEELKISRDA--E
CTDDMYK----MPEKIVPKMHSCEDQINNKS-IENFRYN------------------ISR
------FKGK--QIRKNERLI---------------------------------------
----------------LKK---GWTALHEASVGGFYRTANELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 682)

ITPL
HDAVVNGHHKVAELLLLSGAD

ENSGT00760000119090_5_Linker_1_3 (682, 1434)

PLFRSDNGKCALDEAKDS-RMKRLLEKYVPQCQKHLTSD
QRKRIDTRDVEDVHQHKKTKFSPKNRTGFVCNENSNRQKPEHVEVNKRSKEGFFIN---E
DIYECYPQNSKITRFGKSKH-------------------------NTNV-SEGKGRKNTQ
DKRTQAND-GD---CTSRQAIAISSSKRINTLVTCQQHILQTLDDLSEESHEPSSPTLSS
L---KDGLVNSVAICSVSKEAH-----------------T-RHLDLSEGQEMQFFGLEYI
GQTESGSFSTPSLHKEVKLPLVSTD-QPHVYQEQ-QCSPYISHKNSNSGKKVKT-FNKWE
NSFLSFVKEHSYNY-----NGDFCIAETAITSEMVTCSTECKNYYQ--ENLRNREERDFQ
QLLPSED-HFLQESELKESSLTTFPQQEAVNISNSDKAVISEQHVANYEQCIYGTSFDHS
FGNREQTSLACTRTV-STHEVSKLTSHVEKLKKPQDN-SPRESTPLVNQIDTHIMEKVYV
ELK-EETERNSSDKGQK----PRLFPTVVHSQKIEIINVEKNNEYLPENELIPNKNFCST
KNMNKELTNISEF--NQQEKEIS------------------------HKPDEELPNIIIE
DENIVRNCEEKKEKIDSEIYIPTNTQEYRKDQ-NFG-KRQSFSKATCNQGL---------
---------------------------------------CSCLGKRNARGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHSAARR
GDLSLVQILIESGADVNLKDNAGWT--PLHEASNEGFSDIIVELLKAGANVNCESIHGIL
PLHKAVASNHLKAAEILLQHGANPNQEDQTQKTALDEADNEKMKELLKSYGAIETNNRDE
-------IKSPT--VWSKRYKQ---CLGVEDET-VDPPTPSH--QEERRENFPVHQTISA
ILQDIEENQETLLEFEIRNSKDAEQYIKRMLEIKEIMDNVLSKQKAERDD---LAKKY-R
VSVESFKHGVLREQLANLATRQKKLLVAAKKQKNISLKIQNYKNVTSLSGLPSRKLSSSL
DISSDKESQ-ELTRLENVVQPQLS-----PFSAVNLDCGSV-----------GETPLSPE
TWNDGQNTN-ICLNS----------KKFSRSEMNLKQNES------------DCTLDGFS
NSIHSDTTEKIKLSSQQATFIAQTEHSQK--EN-DLIEMIAKDHEF--C-SPSATTSSLN
ISECTSSLSQNDPYLSTVISDQDLYHCDPK-RRNKKTASQLPPGGVSESV-----AHQRS
A-V-LG-TYTGHALKPCLK-KAASAIPRANDRQISSSFESSHQH-TIKNPSSFSTTPKKK
CMEIKDLMLLGRINPGNNILEFRTQETTHKASILMSGKIKVENGQIYQNPVTWLKDLLGG
DSYVTWNYAWSK------------------------------------------------
------------------------------------------------------------
------

MEEGVQAPDWDSDETVIEGSVTESDLEEKEL--RRLLFDQDASLKSEFGLHPDTRGMCKG
-MPSPEIQLGFKL--REDLQEQMNKNKMMPVLSEDTVLQS-QDET--ERNQALLQTRKNC
SMFIGSFRQSGLSLNH-----------QNIEGPEA-ESP-----EV---LPHIEKELSEG
RDSPEVSLLSGTAITVPDTVAVKETSLIEPEKILAAPNTFFEPRK-EVTMTMTSEETKDE
ESSLETFVSALESLLTSPESTQEERL-------------FELVSDFDRKELMNPLSDSLS
SISI-PLNAWSACH-----RDLLENAK-DDALPAELLE-ALNTLSEAKVETICHRKEGGS
SLIAR----NEC--L------------EVGFNTSQ-TNEDCTQIA-----ETPQDPNPSG
LQTLAHQNITSCEPLSNKRNSNSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEK----NMHSAR
------FKNGK-QIRKNEQFSG---KKEKMKVNKISLGSINRRNIFGENLVYKAALHDDA
DLVHRCIKKGGNVNQPSYA---

PF00023 // ENSGT00760000119090_5_Domain_0 (623, 652)

GWTALHEASVGGFYRTASELLKGGADVNIKGIYQITPL
HDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEYYQKDPKNTKFGKSKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
HKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQHIPETHNDLPEELCEPSSLTLSS
L---KNGLDSSTEACSVSKEIH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLLLHKEIKLPVVTTDKQPHTLQEQ-HRVLYKSHENSNLVPKDER-FNKWE
NSFLSFVKGNSDN-D---GDDDCSTSEKAITSKKVLCSTGGKKHYNFKENLTNKKEMGFQ
QFLLSED-HLSQENELKAVSLTTLPEQEAVNFSHSDNAVISE-HVANYEQCIFGPSFDHS
NGNPEQNSLACMRTL-LTHEASKLTNHVELFKKPQDY-IPRAPTFLMNQTDTHIVEKVA-
--KNCDTERNYIDRDQKIIYSNEPLSIVVHSQVIETTEVEKRRQNHLESETIHDIDSHST
DNMSKELANISKL-SQREKKEIS------------------------HKPDEELTNNISG
DEITIRNCEEIKEKTESEIHMPTNSQEHKTVQ-NFR-KRQSFLKTTCKLGM---------
------------------------------------K--TGGINKRNARGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1527)

LHLAARR
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKVNCENIDGIL
PLHDAVANNHLKAAEILLQNGANPNQKGQKQKSALDEADDEKMKELLRSYGAIETVNRDE
SDAIV-NEKIHA--VRSKTHKQ---CFCDDGKT-IDSSSLSH--QERSSESLSVHQTLSA
VLQDIEEKQEYLLEFEIRNPEDAEQYIEKMLKIKKIMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLAARQKSLLVVAKKQKKISLKIQNCKNVTSLPCLSLRKLPPRS
EISSEKDSQ-ELTTLENLEHPQSG-----SLSP---VSGSM-----------QETQLSPE
TWNYSQNTN-VCLNS-----EAVRRGEFSGNDMNSKQNVS------------DCTLDGFP
KSRHSDGTEKNKLPSQPVAFIGQTEYSQK--EN-DLTEATDKDHEF--Y-VPSPVIGKLN
ISETASVLAENAAHPSNIICDQDLSNYDPK-RGNRKTSSQQSPTGASESL-----AHQGI
A-V-LG-SDTVHQMKPYLK-KPVSVVPCADDSQISSSSGSGQQD-TIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PNKSMFEKTKFGQ-----------------------------------------------
------

MEEGHQVSDWDSDETMIEGSVAD------------------------------------S
-TPSPEIQLGGKL--RGDS-PQRNKNSMLPILNEDSVLQVGSTWAEYVLKM-EMLFLKVD
ALFTVSFPQAGLSLDQ-----------QNAGGKYAWERY-----IKKIWGLGDGSELREE
RDSPEISLLSNIATVVPGMVAVEEKSLVEPEKILAAPNIFYGPGK-EVSLTMSSTETKDE
ESSVETFVSALEKSLTSPESTKGKKL-------------FETVNDFDPRELMNPLSNSSS
SMSI-SLSALSPYC-----RDLLENTE-DDVLPPELLA-ALNTLSEDKTGLG--------
--LSG----NEC--L------------EMEPGMSQ-TDEDCTHRA-----E---------
----------------------------------ETPRLLRRSCR--LEKRKVSQDV--K
GTEDMCK----MPEKILSLNSL----I--------FFSVDTF---LFYEK----NMHSAR
------FQSV--QIRKNE------------------------------------------
-------------RLTLKR---GWTALHEASVGGFYQTANELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 682)

ITPL
YDAVVNGHHEVAELLLLNGAD

ENSGT00760000119090_5_Linker_1_3 (682, 1434)

PLFRRDNGKCALDEAKDS-RMKRLLEKYVPKYQKRLTSG
QRKHSGPGDIEDVHQPKKPKFHPTNHTGVVCNGNSSRPKPEHVKVNKRSKEGLFTN---E
DVYEHHSQTCRITRYGKSKP----LNQTHSP-GLTKGRHCDVK--------DMKGRKNSQ
DKKTQADD-GD---YTSREAVAVSSPRTINGSVACQQHDLQALNDPPKDSHEPCSPTPSS
L---KDGLGNEVEVCSASKEAD-----------------T-HHLDLPEGQETQLLGLECI
GQTKVGSFSGPSLCKEVKLPPVSVDTVYQGP----QNSPYKSPKIIKSGKNNKT-FNKWE
SSFLCFIKNNC---------DDCFISEKVVTSGM----------------PLNRQQGDFQ
QFLPSEV-HFSQENELKEDCITILPQQEAVNFSDLDKVIVSEQHVANYEQCTDETSSAHS
FGSPEHTSLACTRTL-STHEASKLTSPVELFKKPQDN-SPRESNPSMNQTDTHTMEKVM-
--K-EDTKRNYSDKDQK----PRPFPIVVHTQEIGITNVEKKKQNLPESEPMPNINLCST
NNMRKELTDISEF--NQKGKEIS------------------------HKADEKLTN-INE
DASIVTDCLEEKEKIDLGIHMSPHAQEQKKEQ-NFR-ERQSLLKATCNQEM---------
------------------------------------K--TTGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1527)

LHSAARR
GDLSLVQVLIESGADVNLKDNAGWT--PLHEASNAGFSDIIVELLKAGASVNCESVDGIL
PLHDAVAGNHLKVAEILLQHGANPNQKGQTQKTALDEANNEKMKELLKTYGASETNNKDG
NNAAV-TAKIPT--ARSKRYKQ---CLCDGDN---DSPSPSH--QEKGNKDFPTHQTISA
ILQDIEESQEELLEFDIRNPKDAEQYIKKMLEIKEIMDNVLSKQKAERDD---LAKKY-R
VSIESFKHGVLREQLANLATRQRKLLVAAKKQKNISLKIQNYKNVTCLTSPHVRKLPSSL
DMSCDKDTQ-ELTNLDNLVPPQLS-----PFSPVNLDYGSM-----------QETPLSPE
SRNDGQNTN-ICLNS-----KAVRRKEFSRSEMNSEENEN------------DCTLDSLS
KPRHSDSTEKIKLSSQPTPFIVQPKYSQK--EN-DLMETITKD-EF--C-LS-ATKSTLN
ISECSSILSQSDAPVSTVISDQDLSHCDPK-REDKKTASHLPPGGACKSL-----APQRS
A-D-PG-----HPIKSCLK-KSASTTPSASDRQISFSSKSGHQH-AIKKPLSFSTTPKKK
RIQIKDLILQGRIKPGKNILEFKTQETTHKASILLSGKIKVENGQIYQNPVTWLKDLLGG
DSCVTWNYAWSKVTYLGKELLKYVSEEASVPPEAGAGPQ--QPCLPG-------------
--------------ASRESMQGIPYYLQ-INEILLISDQEFLPCHLMDQHWKFYAEHEEL
TF----

MERSAQALDYDSDETVIEGSVTENELEDEELPWRRLLLNRDTSLKSEFCFHSGVNGMWKG
NIPSPVIQLGLKL--GKDSEEQKDKNEVIPTLSEDGVLQDFQDEA--TQNQILLQTRKEF
PAFSVLFPHPEVLWSH-----------QKTRGPEV---------ENCENLPCPEKELSEN
TDSPEISLLSGTSLVASDLVILKEKSLAEPVKTLAVPNTFSETG------------TKDE
ESSLETFVSSLERLLESPEGTQEETL-------------LEIVNNLNPQELMNPLSDSLS
SVSV-PLNALPACY-----RDVLENMKDNDALPAELLA-AINT----LPGPICQGQEKSS
SVSDG----NGC--L------------EVQPTMSQ-IDEDCTQIT---------------
---------------------------------QETPHVLRRSSRLRLKKLKESRAV--A
HTDIMLK----IPEKILSKPLSYEDQTNSIFATENFSKQ----------K----NIHSSR
------FNSE--QIQKNEQL

PF12796 // ENSGT00760000119090_5_Domain_0 (561, 682)

KIK-------------------------------------
------------------N---GWTALHEASVGGFYQTVSELLKGGADVNVKGKYQITPL
HDAVMNGHYKVAELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFRSDHGTCALDEAKDS-FMENLLKKYIPKHKKCHLSG
KIEPLCCRHVETNKEI---------------------------------NNLLVN---KE
YVHEFHQKNSNTKEFG-N-------------------SKPSVNNSRTDV-SKSKGPRNTQ
NKKTQVDD-RD---CNLSQGVAVSSFGRMNKLVTLQQHTVQTLDDLPKESCELSIPIPTS
L---KNGSGNSDEACLISKKAN-----------------T-HILDLSVSQEMQFLELGSI
DQTKAASFSELPLYEEIKLPHVTADQ-PNTNQEQ-CNSPRNPPENNR-SEKGKN-LNEWE
DSFLSFIKGHFADS-----DSDGHTSVKSVASQK-----ECMGHCHNEASTAEGEEMDSL
QVLSSEN-YFSQETEQKAGSLTTYPQEEAVNYCDSNKSLIYEQHFPNYN-CIHGIAFDHS
YANTEYNWMPCTRPP-STQKVTQVTGQVELLKAFQNN-AHREPTPLVNQADTFNVEK---
---KQDTERNYTVKGQKPSPSNSSLHTVVHSQVIEIPTDEKRTQDLPGSKPVNNTDFHST
DNVNKELASSSPQLNEGEEKEIA------------------------HKSDEGLTDNTSR
AERTVRNCKEKGENVDSETHMPSDTQEHRKDQYYFR-KRKGSLEAPCSQG----------
------------------------------------F--TTGIKKRNAKGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHVASRE
GNLPLVKVLIQSGAVVNLKDNAGWT--PLHEASSEGFGDVITELLEAGAHVNCESMDGTL
PLHAAAAGSHLKAAEILLEHGANPNQKDQKQRTALEEADDEKMKELLKSYGAVETSNGNE
ISSAV-TVKRPA--IQPKRYKS---HSCDDEKT-IDPPSPLH--KVKSSESLPAHQTISA
ILQDIEEKQEKLLKFEIGNSEDAEQYIGRMLEIKEVMDNILAQQKTERDD---LAKKY-R
VSMESFKHGALREQLANLATRQKSLLVVAKKQKKIRLRIQNYKNTKPFSGFSLRKPPSSS
DVSSEKKNQ-ESSSLENSVHPQSSSLSPVSLTSISPVDRSM-----------EETPLSVE
IQKDSQKSN-ICLDA-----KAMRKEGFSGNEMNSKENVQ------------GCALDGLL
KSRHSDGTEKIKLSSQPVAFIPQGGNSQA--E-----KTIVKGYRL--D-SSPAVTGTVN
IPEDKRVFSQNDACLPTVPQNQELPR-YPK-RSNKKTASQPPSEEASEPL-----AHQIT
T-V-LD-TDTV-QTKPCPK-KTASVVAHANGLQISPSSGSSYQH-SVKKPSHHSPVSKKK
NVQLKDLILLGRINPGNDILEFKTQETTHKASILLSGKLKVENGKIYQNPVSWLKDLLGG
GNCVTWNYAWSKVTYLGTELLKYVS-EVPVPPEPHSTPQQQQPCLP--------------
-------------GTPRKSMQSIPPYLQ-IKEILLISDQEFLPRHVMEQHWKSHHSEALF
S-----

MEEGVQSLDSDSDETVIEGSVTESDFEDDELPWRRLFFDQDTSLRSEFSVHPGISGLFQG
-IPSPEIQLGHKL--SEGLQEQMNENKMMTVLSADAVLQQPQDEI--VQNQA--VTRKNF
PMFTVSFPQPVLSLNH-----------QNIEEPEA-ENT-----EV---LSHLEEELSEN
RDSPEISLLAGTAITVSGRLAVKEKSLTEQEKILAVPHAFSEPGE-EVSMTMTSKETKDE
ESSLETFVSALERLLTSPDSTQEERL-------------LEIMNDFDPGELINS----QS
SIEI-PLNASSAYS-----RDFLENTK-DDTLPAELLA-ALNTLSETKLGPICHRTEEGS
NLSDE----NGC--L------------EVEPVMSQ-TDEDGTQIA-----E---------
----------------------------------ETPRILRRSSR--LEKLKVSRDA--N
STNDICK----ITEEILPKIPSCEDQINNKSSTNNFRYRI----------------HSSR
------LKSK--QIRKNK------------------------------------------
-------------RLSI

PF12796 // ENSGT00760000119090_5_Domain_0 (618, 682)

KN---GWTALHEASLKGFYRTASELLKSGADVNIKGMNQITPL
HDAVINGHYKVAELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFRSTEGKCALEEAKDS-CMKRLLERHVPKHQRCLISA
RRNSTDPADLDDVQQHKKPKLSSENHIGFVCNENSDKQKPEHVEVNKRSKENLFL--SEE
HIYEHYQKDTKPTKFGNSSKVR----------------------ISTNV-SKGKGRRNTL
HKRTHVDD-GD---CLSEQTIAVSSSRRINRVAIPQQHILQTPNDLPEESCEPSSPTLSS
L---KNALDNNIETYSVSKEIH-----------------T-PSLDLSNSPEMHFLELQST
GQPETISFSGLRVCKEIKLPLVTEDQQLHAHQEQ-HCSPYKFHEYINSNKNKER-FNKWE
NSFLTFLKENFDND------NDCYTSEKTVTSEKVICSKECKSHCNCEENLTNRKEMDFQ
QLLLSED-HFSQEKALN--SLTTLQQEEVIHFSDSDSIVISDKHIANHVQCMYGASFDHS
HGNPEQTSKAYTRTL-SIHEVSKVTSHVELVEKPQDN-SPREPTPLMNQTEKHIVERK--
----QDTKGNDTKKCQITSSSNKPFPTVDHSQGVQITKVEKKRQDLTESEPMHNIDFHST
DNMNKEMNIISQSINQVEEKKNP------------------------HKSDEELTNDINV
DERAIRNCEDEKEKMNTETYMSPNIQEHKKGQ-NFR-NRQNFLKVTYNQGL---------
------------------------------------Q-ITAGINKRNVRGQSR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLVKVLIESGADVNLKDNAGWT--PLHEASNEGFNDIIVELLKAGANVNCENIDGIL
PLHDAVASNHLKAAEILLQHGANPNQKDQKQKTALDEADNDKMKELLKSHGAIEANNRD-
-------EKIPA--VRTKRHKQ---CFCDVDKN-VDPSSLSR--QEKTRESLPVHETISA
ILQDIEEKQENLLVFEIRNPEDAEQYIEKMLEIKEIMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLATRQKSLLVVAKKQKKISLKIQNYKNVTSLSDPSLRKLPSSS
HIFSEKDNK-ELTSLENSVQPHSG-----SLSHINIACRSI-----------QETPLSLE
TCHDSHNTN-LCLAS-----EAVRREEFSGIEMNSKQNVN------------DCTLDGLF
KSRYPDSS-DNKLSSQPDAFIAHTEYSQK--DN-DHTETTAKDCGL--Y-SPFAITGTLN
GSKHTSILSQKNAHPSAVIWDQDLSQYDPK-RGNRKTASQQPPGGTSESW-----AQQAV
A-V-LG-TDTVHQTKQYLE-KTASAVPHINNSQVSSSSGSGHQH-TIKKPLNYSTTPKKK
CMQIKDLILLGRMNPGNNILEFKTQETIHKASVLLSGKIKVENGQIYQNPVTWLKDLLGG
DSYVTWNYAWSKVTYLGKELLKYVSEEV--PPEPNVVPQQHQPCLPG-------------
--------------TSRESVQNIPHHLQ-INEILLINDQEFLPCHIMDQHWKFYVESLLF
S-----

MEEGVQDPDWDSDETVIEGSVTESDLEEKELRWRRLLFDQDTALKSEFSLHPDTRGMCEG
-MPSPEIQLGFKL--KEDLQEQMSKNRMMPILSEDTILQS-QDET--ERNQALLQTRKNC
SMFIGSFHQSGLSLNH-----------QNSEGPEADETP-----EV---LPHIEKELSDG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAAPNTFYEPRK-EVILTVTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------FELVSDFDSKELMDPLSDSLS
SISI-PLNAWSACH-----RDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EVKFNTSQ-TNEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCEPLSNKRNSHSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDSKEK----NMHSRR
------FKNGK-QIRKNEQFPG---KKEKMKVNKISLGSINRRNIFGENLVYKAALNDDA
DLVHHCIKKGGNVNQPSYA---

PF00023 // ENSGT00760000119090_5_Domain_0 (623, 652)

GWTALHEASVGGFYRTASELLKGGADVNIKGMYQITPL
HDAVVNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEHYQKDPQNTKFGKSKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCVLETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKETH-----------------I-QNLDLSDSQEVQCLELESI
DQTEVVSFPGLSLHKEITLPLVTTDKQPHTLQEQ-HHVLYKSYENSNLVQKDER-FNKWE
NSFLSFVKGNSDND-----DDDCCTSEKAITSKKVMCSTGCKKHCNFKENLTNRREKDFQ
QFLVSED-HFSQENELQAVSLTTLPEQEAVNFSHSDNAVISE-HVANYEQCIFGPSFDHS
HGNPEQNSLACMRTL-STHEVSKLTNHVELFKKPQDY-IPREPTFLMKQADTHIVEEVA-
--KNCDAERNYTDRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPGM--------
-----------------------------------------------KT-----------
----------------------------------------GGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARK
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKINCANIDGTL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLKSYGAIETDNRDE
RDAIV-NEKIPA--VQSKRHKQ---CFCDDGKT-IDSPFLSH--QERSSESLSVHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLNIKEIMDNVLAKQKAERDD---LAKKY-R
ISIESFKHGALREQLANLVARQKSLLVVAKKQKRISLKIQNYKNVTSLPCLSLRKFPPRS
ENCSEKDNQ-ELTSLENLEHPQSG-----LLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDVNSKQNVS------------DCTLDGFP
KSQHSDGTENNKLPSQPVAFIGQTEYSQKEKEN-DLTEATDKDHEF--C-IPSPVIGKLN
ISETASVLAENSAHPSNIICDQDLSNYHPK-RGNRKTTSRQSPTGASESL-----AHQGV
A-V-LG-SDTVHPMKPCRK-KSVSAVPRADDSQISSSSGSGQQD-IIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKSPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFGQGTSRELMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFYVGCEEL
TL----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------V---------
------------------------------------N--TAGINKRNAKGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHVASKG
GNLSLVKMLIESGADVNLKDNAGWT--PLHKASSGGFDDIIIELLKAGANVNCENVDGIL
PLHGASAGNHLKAAEILLEHGANPSQKDQKQRTALDEADDEKMKELLKSHGAIETAHGEE
RSSIV-PVKIPA--IRPKRYKP---FICDNDKA-VGSPAPSH--KAKRSESRPVHQTISA
ILKDLEEKQETLLKFEIRNSEDEEQYIEKMLDIKEVMDNILAQQKTERDD---LAKKY-R
VSMESFKHGALREQLANLATRQKSLLVVAKKQKKIRLKIQNYKTATPSSGNNLRKLPCNS
DISSDKTSQ-DPPGVGNSALAQSGSLSPNNLA-----YRSM-----------QEMPFSPE
IQSDSQNTN-ICLNA-----EAIRGEEFPGSDTNSKQNVQ------------DCASGGLL
KST-SDDTEKMTSSSQPVALTSQAEYSQA--EN-FFPETSVKGYGF--D-A-PSLTGTIN
ISEDKSIFSQNDVCLPAFP--QNLSRCKPK-RRNKRTGSQQPSEGASKPL-----AQ-TV
A-I-LD-TYTARQTKPCLK-KSASVALNADSMQISPPSVSAHQP-SSKKAPHHSTTPRKK
TVQLKDLILLGRINPGNNILEFKTQETTHRASVLLSGKLKVENGQIYQNPVTWLKDVLGG
GSYVTWNYAWNKVTYLGKELLKYVSEAPPVSAEPSSTPQQHQPCLSGVCSDRRK---SQK
VTNSFWQKSFLGTGTSRESMQIIPHYLQ-IKEILLISDQELLPCHVMEQHWKFYVECKKL
SF----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MFL---GG
-------CFV----------------FSKILH-NNQHLAENSVLLGKFTEG---------
------------------------------------K--TSGIDERNATGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GRLSLAKALIESGADVNLKDNAGWT--PLHKAASNGWSDV--ELLKASANVYCENVDGIL
PLHDAVANNHLKAAEMPLQHGANPNQKDEKQKTALDEADDENMKELLKSCGAVETDSRDE
SDAVA-TVKTPY--VRARRRKQ---CICDDSKT-VDTPSISH--QEKTEENLSMHQTISA
ILQDIEEKQENLLEFEIRTPEDAEQYAGKMLEIKEVMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGVLREQLANLAARQKSLLLVAKKQKKISQKFHTYKNATSLSGLSFRKLPSSS
ETSNEKDRQ-ECISMENSMQPQSG-----SLSPVSLVCKGM-----------QETQLSQE
VWHNNQSTH-TCLNS-----KTVRREEFSGSELNSKQNIN------------DCTLDRVS
KSRHSDGTNQIKLQSQSVTFIAEAEYSPK--EN-DLTGSTAKGHVS--F-SPSAVTGTLK
ISATTSVSAHHDAHPSSVIYDQGPSDCDPK-EGNRKTAPHQAPGGTSESL-----AQQGV
D-V-FG-SDMGQQLKPYLK-KSALTVPHANDTQSCSSSGSGYQH-TVKKPSNYNTTAKKK
CMQIKDLILLGRLNPGNNILEFKTQEATHKASVLLSGKIKVENGQIYQNPVTWLKDLLGG
DSYVTWNYAWSKVGHS--------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------M---------
------------------------------------K--TAGINKRHAKGESQ

PF00023 // ENSGT00760000119090_5_Domain_2 (1434, 1461)

LHLAARR
GNLSMVKSLIASGADVNLKD

ENSGT00760000119090_5_Linker_2_3 (1461, 1463)

NA

PF00023 // ENSGT00760000119090_5_Domain_3 (1463, 1495)

GWT--PLHEASNVGSNDIIVELLKAGANVNCE

ENSGT00760000119090_5_Linker_3_4 (1495, 1497)

NL

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1528)

DGIL
PLHDAVANNHLKAAEILLQNGADPNQKTQKQKTALDGTDDEEMKELLKSYGAIETNNRDE
SNVII-NVKIPA--VRSKRHKQ---CFRDDGLT-VEPPSFSH--QGEIRENLPVHQTLSA
ILQDIEEKQEDLLAFEILNPEDAEQYIEKMLKIKEVMDNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLADLATRQKRLLVAAKKQKEISLKIQNYKNVTLLSGLDLRKLPPSS
ETSSEKESQ-EPTSLENSVQPQSR-----SRSAVNFVCGSM-----------QETQLSLE
TCNYSHTTN-ICLNS-----EAVRREEFSGNEVNSKQNAN------------NYTLDALS
KSRCSGD-TEIKLPSQPVAFILQTEYTQK--EN-DLTEITAKEHEV--S-SPSTVNGPLN
ISETTSVLAQNDAHLSTVICDQDLSN-DPK-RRNRKIAFQQPPREASESL-----AHQGI
A-V-LG-T--AHQMKSCLK-KLASTNPLAKDSQI-SSSGFGHQH-TIKKPLNSSTAPKKK
CMQIKDLILLGRINPGNNILEFKTQEATYKASILLSGKIKVESGQIYQNPVTWLKDLLGS
DSYVTWNYAWSKVTYLGKELLKYVSEEVPILPEPNLVCQQHQPCLPDIICYSDDPV--QE
QNKLVSEKMEFGQGTSRELMQSIPHYLQ-INEILLISDQEFLPCHIMDQHWKFYVECEEL
TF----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------QELSTD
SDSPEISFLSGTTTKVSDVVVVKEKTLIEPEKISAIPNQFSQSGK-EATLTMNSEETKDE
ESSLKTFVSALERLLTSPEITQEERV-------------FEIMSDFEPEELANPSSNS--
---PSSISVSLTCH-----RDLLESTK-DDALPTELLA-ALNTLSEGNVGPFCHRKEGGS
SLSVG----SKY--S------------GVEPKMSQ-TSEDCTQIT-----ETLEDPSPFG
LQTLVHQNVTSCDPLNNKGNSNSVEN----KSDQNTPCVLRRSSR--L---KAGRDA--K
HTDNVCK----MPEKILPMILLSEDQTNNNSSSKNFRIQDPALMIKGKGK----NMNSTR
------LKSGE-QMQRNKKLAG---KNEKMKRNKISLSSINRRNI

PF00023 // ENSGT00760000119090_5_Domain_0 (586, 618)

FGENLLYQAALHNDV
DLVHHYIIKGGNVNQTSYA---GWTALHEASVGGFYQTASELLKGGADVNIKGM

PF00023 // ENSGT00760000119090_5_Domain_1 (655, 687)

YQITPL
HDAVINGHYKVAELLLLNGADPLLKS

ENSGT00760000119090_5_Linker_1_2 (687, 1429)

DCGKCALDEAKDS-CMKRLLEKYIPKHQKHLISG
KIKLPCYICLS-YVLFLKPKFSSKNLIGFVCDENSNRQKPELVKVDKGSKEGLFIN--KE
DVYEPYQKASKDTKFGKSKHKQSTLNQIHSTRGLRKKSLQNVKSPNTNV-SNDKGRRNTQ
HKRTQVDD-AKQEICIPRKITAVSSFRRRNKLVTGQQDNLQTFDDLPEKSQKLFSPALSS
L---KNGLGNNIEACSIPKETH-----------------T-QSLDLSDNQEIKFLELEST
DQEEAVLFSGLSLQEEINLPLVTTDQQPHAHQEQEHFSPYKSPENSNSGQKGES-FNEWE
NSFASFIKENFSNV----DDVDCFTSEKTVACKRVVCSTGCKNHCNYNENITNREEMDFQ
QSFPSED-HFSQENELKACSPIILPQQEALNLSD-------PEHVAKYEQCVCETSFDHS
HGNPEHTSPACPRTF-STQEASKLTSRVKLFKRPQDF-SSRAPTSLTDQTDTHIVEKVN-
--EGDGTKRNYNDKSQKTSSSNGSLSTLVNSQVIETTTVEKGKQDLPESKTTHDTVFDST
DNISKELTNISQL-RQKEEKETS------------------------HKPGMK-------
------------------------------------------------------------
---------------------------------------TAGINKRNA

PF00023 // ENSGT00760000119090_5_Domain_2 (1429, 1461)

RGESRLHLAARR
GNLSLVKALIDSGADVNLKD

ENSGT00760000119090_5_Linker_2_3 (1461, 1462)

N

PF00023 // ENSGT00760000119090_5_Domain_3 (1462, 1496)

AGWT--PLHEASSEGFDDIIVELLKAGTNVNCEN

ENSGT00760000119090_5_Linker_3_4 (1496, 1497)

L

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1529)

DGII
PLHDAAANNHLKAAEILLQHGANPNQKNQKQKTALDEADDEKMKELLKSYGAVETDNRDE
SNVIV-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------ELSEG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAAPNTFFEPRK-EVILTMTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------SELVSDFDRKELMDPLSDSLS
SISI-PLNAWSACH-----RDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EVKFNTSQ-TSEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCEPLRNKRNSHSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEK----NMHSPR
------FKNGK-QIRKNEQFPG---KKEKMKVNKISLGSINRRNIFGENLVYKAALNDDA
DLVHHCIKKGGNVNQPSYA---GWTALHEASVGGFYRTASELLKGGADVNIKGVYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVMNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEYYQKDPQNTKFGKSKHTQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRKKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCILETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKETH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLSLHKEITLPLVTTDKQPHALQEQ-HHVLYKSYENSNLVQKDER-FNKWE
NSFLSFVKGNSDND-----DDDCCTSEKAITSKKVMCSTGCKKHCNFKESLTNRKEKDFQ
Q-------SFSQENELQAVSLTTLPEQEAVNFSHSDNAVVSE-HVANYEQCIFGPSFDHS
HGNPEQNSLACMRTL-PTHEVSKLTNHVELFKKPQDY-IPREPTFLMKQADTHIVEEVA-
--KNCDTERNYADRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPDEELTNNISG
DGITIRNCEEIKEKTESEMHMPANSQEHKTVQ-NFG-KKQSFLKTTCNLGM---------
------------------------------------K--TGGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1511)

LHLAARR
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIVVELLKAGAKVNCANVDGTL
PLHDAVANNHLK------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
-------------------------------MTSDLMKTHSLRRIETEQPQPLLLNGKND
MTQMVTFPPADFPPNSVVHVEESSSMGLNVGIPGFYQRAEMKETNWLHWIPGTPDRHSP-
-YYNEENIISGSTTPICYRREEQETSLRRTLP--SKPD----PLR-PIMLTWSARDFQEV
DRSHKPML----SMGGSPELGMEKTPFKPRILAQEPPNQWRLLSETESPQLTSPSNHSLD
CVEE-T------LF-----SGTSESEK-NDDLSAELQI-VLKTLSDSGSEPTSQGAEKGS
GLNSK----SEPSCTQTDYRGTEIPNNNLEPECSVQSFEAVQQLAEAEAKDTSDKQVVLD
SKTLDHQNVISCGEPSNEKNSDRNEISPGIVTATDSACTIRRSSR--LKTLATRNAA--K
SMDGVNNRRVEDPQKPLPYGIR-------RRPTESLRTQDPVVRNERVREYSPSSQQSSS
------TRNSGEEIRRSKRIANKMAKE--PPKKVMKLSNINRRDIYGDSLLHKAAERGDS
DLVRECLKLGANVNRPNYA---

PF00023 // ENSGT00760000119090_5_Domain_0 (623, 652)

GWTALHEASVEGYYQTVHELLKRGADVNCKGMDGTTPI
QDAVQMGHYEVAELLLQYGADPLLQDDNGECAVDLTEDP-NFKRLLENYVIKSRRRQRAV
QGNT--SLDVDTSSQHKKLEPIQKG---PIKGDSSRTTRQRNANVNRRIHMVLRPQKS--
------SEPRRSRRLAQIKIKQST-NDKRNT-GSRQTRTQEVRDHKADKTAHGKTTRSTS
RRDKPVRE-SS---IT-SMKEVISSSRRITRSATQKEHSHRN-------GCDISGLTDQS
AKATKSDIGNETEAN---------------------------------------------
---------------------------------------------LVSGRKK--------
----------------------------------KTCGNSSVQEMHFKSR-DPSDRRGQV
DFLDSES-AA---------SEKVLPQPGDDRVS---GNIVGE---RNSEGCSRGRNRENH
SG----------------------------------------------------------
---------TYM-------------YTRLQTQEKGV----RMGQD--LQETFLSQDLCSS
GNVDEDSINWAPY--NPTG-----------------------------------------
-------------------------QEVSGPS-ELG-KEKSVGLP--TQSA---------
------------------------------------QETTTQGNKRNAQEENRLHSAAEK
GDLTLAKALIKSGARVNQQDHAGWC

PF00023 // ENSGT00760000119090_5_Domain_3 (1466, 1495)

RTVLHEASKRGFTEIIIELLKAGANVNSK

ENSGT00760000119090_5_Linker_3_4 (1495, 1497)

DL

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1529)

DGIS
PLHDAVLGNHLKAAEILLRYRADPKQKDDNERSALDEATDEKMKMLLKSFGPHETRKSSN
RMFFS-EGEETS--NRSRKSQQ---CYCHGSTD-VDRPSFSH--QDQMRNTSPTHESISA
ILQDIAEKQENLLQFEIRTHEDSEQYSQKMLQIKGFLDDVLAKQKEERDDLAKRYRSR-R
ASKDSFKAGALKEQLTNLASRQKRLLVVAHKQREVSHKIQNFKAMKQA---SLRQQATNS
GSLGDDDKQ-KPAAAERTKHPLAALLLLSPATSCSLGSGSETHLFSESRFLDQADSQSPN
SWVREEETE-----------EALGQEECSLNDKTAKRKAG------------GDSSEQTS
TSHYPDVTEKGAVALEPVVFISQTKYSKQ-KEN-HLSEIAPKESES--P-DPSAKPRTLN
ISEATSEIVKKNSCQPTTAHSQAPACWNPPGSTSMKAASQEPPTERSERSSRSLPMHQRG
P-V-GG-REALLKTKPDHP-KSTQVDGLANDSQKSFTPLSSSQP-RKQESSNHRTERERR
NVRIRDLMLQGKITPGEDVLEFKMQNLSYKASILPNGKVKDESGNIYISPIAWIKQLLGS
NISVTWKYVWNKVTYLGKELSKYISEEVQKSVEPKLPPP-SQPCPSVY------------
----------TGSSSQSTSKPDITHILQ-LKEILLISNQELLPSQMMDQQWQFYVECEEL
TF----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------ASDSDS-DETIIEGSVTDSDE
EGEA---------------LHWRRLY-------------FDQDTSLRPEFSFHPG-----
----------------------------------------TNGMGQGLSSPEI---PLGL
TLRKDSQEQKNK--S------------DVMPIL------SEDTIL-----QTIEDPKPFG
LQILTHENVISSEPLNNEGNSNAVKN----TSVLKTPCILRRSSR--LEKLKADRDA--K
HIDDTCK----MTETILLKTLSCENQIN-KSSTKNFRFKSDQI-----------------
--------------RKNERL------LNGEKMNKLCPATINRRNIFGENLLYMAALRDDV
ELVRCCIKNGGNVNQQSYA---GWTALHEVCVGGFYRTASELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 686)

ITPL
HDAVINGHHKVVELLLLNGADPLLR

ENSGT00760000119090_5_Linker_1_3 (686, 1434)

NENGKCALDEAKDS-CMRDLLEKYIRRHKKHRTSA
RRKTAD---------------------------------PAHVEDVYQFKVCLLIN--KS
DIYEYYQENSNTTEFGKSKNKESTVSQTCS-MGHRKGYLYNFRDSRTNV-SKTKGKRNLK
KHEKSQDSQVDEEYYNSRQTAISSSVTVDDKSVTHQQFTVQSLDDFREESFGFSTPTLSS
L---KNGLGNNSEACSVSKELH-----------------T---LDLSDSQEIQSLELKSI
DQTEVSLFS---LHKETVLPLVTTEDLLDIPQK-QCNSHYKSLENSCTYKKSKN-LNKQE
NSFQSFTKDQVVN-----DDVDFSTSEKTI--------TSGENHSNYQEHVTNVEEMDSQ
GSLPSED-HHSQKNELKAGSLTTLSQQEDVHFYDSDSTVISEQHAANCGQCIYETPFNHS
HVNPKQTSLPCIRRVPSTYEVSKITSHMEMFKKLQDN-DLRGQTPSVNQTEAHNIEK---
---EQDTERNYTVTDPKPTSSNCPFPTTVHSQEIGTTRVGKMRPNFPEHD------FLSP
NKMDKGLTNISQL-HQKEDKETS------------------------HKSDEELTSSAKE
YERTIRNCKKKK-EMDSEIHVPPKIHEHKKEKVSVL-------FDKFT------------
------------------------------------EWNKTGI-NKNGRGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLASRR
GNLCPAQVLIESGADVNLQGSAGCT--PLHEAANEGFNDIIVELLKAGTNANCENIDGTL
PLHEAVASNCLKAAETLPEYRAHPNEKDQKQKTAWDGADDDRMKVLLKSYGPSEADKGDE
STSTV-PVKIPA--VQPKRYQR---YACDGDKT--VLPLLLH--QTKRNESLSVHQNINA
VLQDIEEKQEHLLEFEIRSPEDAEQYIEKMLAIKEAMDNVLAQQKAERDA---LAKKY-R
VSMESFKHGALREQLANLATRQKSLLVVAKKHKQIRLKIQNYKSSTSFSGLSLRKLPSSS
HITNKKKNQ-ELTSLENSVNPQSD-----SLSPVNLACKSM-----------KETPLSLE
TWNDSQNTN-ICLNE-----QAM-REELSGNEMNSKQNDN------------DATVAECL
KPTYCHGTEKMELSTQLVAFVEGN----------DLAETTAIWHGVSSP-PAATTTDTLT
FSEDTNVLSQNYACPSTVTWDQDLLYCDLK-RRHKGTDSQQPLREISESL-----AHQGI
A-V-LG-SDTVHQIDPCLN-KTASAVSHASNTHVSSSSGSDQQQ-TIKKTAPYTTVPKKK
SMQLKDLISLGRIDPGN-VLEFKTKETTHKASILLSGKLKVENGQIYQNPVTWLKDLLGS
DSHVTWNYAWNNVSYF--------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MKKV

PF00023 // ENSGT00760000119090_5_Domain_1 (658, 687)

TPI
YDAVLNGHYKVAELLLQNGADPLFRN

ENSGT00760000119090_5_Linker_1_2 (687, 1430)

DYGKCALDEASDP-RMKQLLECYIHKPSP--TPD
QKNRNEQLLPEDMQPHQKQECSSRKCTQYFNNENSREMKENKTEVPEKNKGNLLKN--KG
VVDENHQKISKNNKLIPTRNKQSTIDQINVK-EPPKIHMQNISEPKNVV-LKGKRKTSTI
PKGTEKSG-RK---SN-IKIVPLIPSKRIMRSIAH----PETFCDLSEKSSMLTSSAAPM
L---KNDLCHNSEDFSVFQGRDACENDITSPILPSQEERSQNTGSADCQKECNFLESETV
EPAEAIPLSRLPSCEEAELPLVTEGNYGAACCE--KSLPCEASSFNNPNHKSEN-VTEWE
KCFLSFVDRNIDGDNNDSSDDGGCISEGTALPEKFICLVNDENQNPCEIDSKHEEESNSQ
HYLSSETPSLLQENGLQAGSTMTITQQHIVNLSDSDCTVISERYVVNDGQNIKRTTSDV-
--DPGQIPLNSTRSL-SMLDLSGQSGVS---TSLQN-INATAPDSFVNQIDEERVTNVRA
E---ESSQRTCSEKTQE-SHQKRTERTEKQSHEKEATNVEENQIELSESEVAPNENVQSI
KNMNGDLSGTSQS-KQGTEKMVPSQSEAWLFCTPATCPTTPQSPLLDLHPDKDMTDTVNK
EQNTEISHKKEKEKRSPEICASRNLQPCEKNS-KIKRKRQDLQGITYSQELSSSISTNKD
LLNPLQQENSPDPKLPNISEPSASSKKDTQDLPDKLSCKTTKVQKRNSK

PF00023 // ENSGT00760000119090_5_Domain_2 (1430, 1461)

GKSRLHLAAKR
GDLSLVKALIESGTQLNQKD

ENSGT00760000119090_5_Linker_2_3 (1461, 1463)

NA

PF00023 // ENSGT00760000119090_5_Domain_3 (1463, 1493)

GWT--ALHEAANKGFNDVLVELLKAGANVN

ENSGT00760000119090_5_Linker_3_4 (1493, 1497)

SESL

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1528)

DGLL
PIHNAVSGNHLKATEILLQHGANPNQKDGDQKSALERAENEKMKKLLKSYNRNETREIYH
NKVPG-IHSETH--NQ---------RGLKGGKT-DSPSFLET--PRKSNCLTSAHEAICT
ILQDIEEKQENLLLFEIRTPEDADQYSEKMLQIKDIMDSVLAKQKKERDH---LAKKY-R
Q---SFKCGTLREQLANLATRQKSLLMVAQKQKKLSQKIQNYKNTRNKSALDVREEPLDS
RNSNEKDKGSYPPQVERTRQPGSVSVPVQTPADPTMGMSRKTHWATESR---QE------
---DSQHSG-GCLSERGMPEKTAESQCFPFTGQISKRRPV------------DHSLERTW
KSRKTHGIKRVKLPPQGVTSSALAEYLQE--GN-YSTVITAKGSKS--L-NPSAITETLN
VLETTSATVRDNTHQPSTVCHLALGSSLLPGNTAKKTVSQDTPRTVSELLVQSFLTHQGN
AG--LD-SGTLPRMKLNHT-EARPVGALADSSQINFSSEPANQNNNKPEPLNSRAETKVK
KAQIKELISLGRIKPGNDVLEFKMQDATYKASILLNGKIKAKNGEIYQNPITWIKALLGS
NISVTWKYVWNKVTYLGKELCKYITEEVPVLAEPNEVLQENQPCLPG-------------
--------------PSSETSQNLTHYLQ-LNEILLISDRELLPCHMMEQHWKFYMTSKDA
PF----

MENGAEASDCDSDETVIEGSVTENEPEDEELPWRRLLLNQDTTCRSEFCFHSGVDGMQKG
-IHSPEIQLGLKL--RKDSQEQNNKNKLLLALSEDLVLQDPQDKT--AQNQVLLQTTKEF
PVFTVSFPHPEVSWSH-----------QNTGGHEA---------ENCENLPHSKKELREN
SDSPEVSLLSGTSPVAPDLVALKER-LTEPVKTLAVPNTLSEPGE-EVTQTMTSKETKDE
ESSLETFVSTLEKLLESSECTQEERL-------------LEVMDDFNPQELFSTLSNSLG
SVSV-PLNAWAAQG-----RDELENKA-DAALPAKLLA-AVNT--GADVGPSCQGQEKSS
SVSGG----NGC--L------------AVQPIMSQ-VDEDCTQIA---------------
---------------------------------QETPRVLRRSSR--LEKLKASRDV--V
HTEAVLK----KPERILSNTLSFKDQINSIFTTDSFSKR----------K----NMHSSG
------FKNE--QIRKSEQLR

PF12796 // ENSGT00760000119090_5_Domain_0 (562, 682)

KK-------------------------------------
------------------N---GWTALHEASIGGYYQAVSELLKGGADVNVKGKYQITPL
HDAVMNRHYKVAELLLMSGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFRSDHGTCALDEAKDS-SMETLLMKYIPQQKKCHLSA
QRNSTDPAHVEDMFQNKKPKLSSNNYTEFICDENFDRQEPGHLEINKGSNNLLMS---KE
YVCEHCQKDSNTTKFGKS-------------------NLNSVKNSRTNV-SKRKGQKNRQ
QKKTQVDD-RD---CNLSQKIGTSSFRRTNKLLTQQQHAVQTLSDLPEESFELSTTTLSS
L---ENGIGY-NEACLVSKKSD-----------------T-HVLDSSDGQE-----LESV
DQTEAASVSELSSYKEIKLLPVTTHQQPHTNQEQ-YSSPYKSLGNNSSNEKGKA-TNKWE
DSFFSFIKGRSADS-----DSDCHTLDKSIASPK-----EGMSHDHHEEI-MTGQEVDSQ
QRLSSEN-YFSQENDLKVHPLTTHPQEEAVNFCDSN--LISVQHTPDYKNCLHEISFGNS
YAKTEQSSTSCTRPP-STQKVSPLTVEVELLKGLQDSLAHRDSSPLVNQAGIHSLER---
---KQDTDKNYTKKGPNTSSSSRPLPTVVHSQVIEITKAEKRREDLPGNEPINNTDFYST
D-INKELANS-SQLNQRKEKENV------------------------RKSDAELTHNDSE
AERTLKSCEEKKKNMDSETHSPCDIQEHRKDQ-NFR-KRKCSLKAPCSQGV---------
------------------------------------N--TTGIGKRNKKGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHVAARG
GNLSRVKVLIEARADVNLRDNAGWT--PLHKAASGGFDDVIIELLQAGANVNCENIDGIV
PLHGASAGNHLKAAEILLEHGANPNQKDQKQRTALDEADDEKMKELLKSYGAIESTNGEK
RNSTD-LVKIPT--VQPKRYKQ---FICDNDKA-IGSPVPSH--KAKKSESLPVHQTISA
ILQDIEEKQENLLKLEIRNSEDEEQYIGKMLEIKEVMDNILAQQKTERDD---LAKKY-R
VSMESFKHGALREQLANLATRQKSLLVVAKKQKKIRLKIQNYKNATAVSGVGLRKLPCNS
DISSDKKSQ-EPPTMGDSAHAQPGLLAPVSLA-----YGSM-----------QEIPLSPE
IESESQKIN-ICLNA-----EAIRREEFSGNDINSKQNVQ------------DCTLGGLL
RSKPTDDAEKIASSSQPAALTPHAENSQA--------EATVKGCGF--D-S-SALTGTIN
ISEDKSIFSPNGACLAADPHSQKLSRCNPK-RRNKKTASQQPSAGAAEPL-----PQ-AP
A-V-LD-TYTVHQTLPCLR-DSAAAASHTDSTQSSLSSASAHQH-PTKTVPHRNTTPRKK
AVQLKDLILRGRINPGNNILEFKTQETTHRASVLPSGKLKGENGQIYQNPVTWLKELLGG
GSYVTWNYAWNTVTYLGRELVKCVSEEAPMSAELN-PPQLHQPHLS--------------
-------------GTSRESMQTIPHYLQ-IKEILQISKQELLPCHVMEQHWKFYVGRSHS
EALLSW

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----IFRFMNNLVLAEKPRFSSKNHILYICDENSNTLKSEHVKVDKRSKEHLFIN---K
DIYEDYQTDSKNTNFVKSQRKQSTLNQRYSK-ELRKGSLHNVRDPSTYV-SKGKGRSSTQ
CKRTHVDD-GD---CSLRKTIAVSSSRRIEELVTYQLPILHILDDPPEESCKSSSPKLPN
L---KNELDNNNKACSNSKETH-----------------T-QSLDLSDGQDVNFLELESV
DQTEAVSSLGLSLQKEINLPLVTADQQAQTDQEQ-HFIPYKSHEKNNSGEKDEC-LNKWE
YSFLSFIKESFDDD----GGSDYSTSEKTVASKIVICSADCQNHHHCKENITNREERGFQ
ELLPSEQ-HLSQENEIKTGSPTTLLQQEAVNFSDSDNIVISEQHVANYEQHI---SFNHL
YDNPEQTSLSCTRTL-SAHEISKLTSHIELFKRPQDY-SLKAPALLMNQTDIHFMEKIN-
--EKQDTKRNYTDKGQK-SYSNGPLSIIVHSQRTETNKIDKSSQYLPDSEIMHNTNFHSS
DNMNEELINISQL-SQRGEKEIS------------------------PKPDEKLINSINR
DENTVGNFEEKKEN--SEIQNLSNIQEHKKAK-NLR-QRQNSLKATYSQEM---------
------------------------------------K--RPGINKRNTKGESQ

PF00023 // ENSGT00760000119090_5_Domain_2 (1434, 1461)

LHLAARR
GNLSLLKVLIESGADVNLKD

ENSGT00760000119090_5_Linker_2_3 (1461, 1463)

NA

PF00023 // ENSGT00760000119090_5_Domain_3 (1463, 1495)

GWT--PLHEASSEGYNDVIVELLKAGANVNSE

ENSGT00760000119090_5_Linker_3_4 (1495, 1497)

NL

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1528)

DGIL
PLHDAAANNHLKAAETLLQHGANPNQKDQKQKTALDEADDEKMKQLLKSYGAVETNDRDE
SNALA-TVKIPA--VRPKKHKQ---CFCEECQT-VDPASLSY--QEKTKESLPVHQTISA
ILQDIEEKQESLLEFEIRTPEHAEQYIEKMLQIKEVMDNVLAKQKAERDD---LAKKY-R
VSMESFKHGALREQLANLATRQKSLLSVAKNQKTISQKIQNYKSVTSFSGLSLGKLPSCS
EISSEKKHQ-EFTSLENSMQLQSG-----SLSPARLVNGNM-----------RETQLSFT
VQNNHQDTNVCCLNS-----ETVRRRDFSGNELNSEQNIS------------DRILDELA
KPSHSYDNEKIKLPSQPVASTAHAEYPPK--EN-YLSETADKGHES--C-SS-IETGILN
ISETTSVLAQKDAHPSTLLCNQALSNCD-Q-RGNRDTASQQLPRGASESL-----AHQGI
A-V-LG-SDTVHHMKPYLKKKSASAVPYANDSQSISSSKCDNKH-ALKKP------SKKK
CMQIKDLILLGRINPGSNILEFKTQETTHKASILLSGKIKVENGQIYQNPVTWLKDLLGG
KSSVTWNYAWSKITYLGKELLEYVSEEEPIPPETNLVSQQHQPCLPG-------------
--------------TSIESIQNIPHYLQ-INEILLISDKEFFPCHLMDQHWKFYVESEEL
PF----

MEEGVQDPDWDSDETVIEGSVTESDLEEKELRWRRLLFDQDTALKSEFSLHPDTRGMCEG
-MPSPEIQLGFKL--KEDLQEQMSKNRMMPILSEDTILQS-QDET--ERNQALLQTRKNC
SMFIGSFHQSGLSLNH-----------QNSEGPEADETP-----EV---LPHIEKELSDG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAAPNTFYEPRK-EVILTVTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------FELVSDFDSKELMDPLSDSLS
SISI-PLNAWSACH-----RDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EVKFNTSQ-TNEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCEPLSNKRNSHSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDSKEK----NMHSRR
------FKNGK-QIRKNEQFPG---KKEKMKVNKISLGSINRRNIFGENLVYKAALNDDA
DLVHHCIKKGGNVNQPSYA---GWTALHEASVGGFYRTASELLQGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVVNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEHYQKDPQNTKFGKAKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCILETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKETH-----------------I-QNLDLSDSQEVQCLELESI
DQTEVVSFPGLSLHKEITLPLVTTDKQPHTLQEQ-HHVLYKSYENSNLVQKDER-FNKWE
NSFLSFVKGNSDND-----DDDCCTSEKAITSKKVMCSTGCKKHCNFKENLTNRREKDFQ
QFLVSED-HFSQENELQAVSLTTLPEQEAVNFSHSDNAVISE-HVANYEQCIFGPSFDHS
HGNPEQNSLACMRTL-STHEVSKLTNHVELFKKPQDC-IPREPTFLMKQADTHIVEEVA-
--KNCDAERNYTDRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPGM--------
-----------------------------------------------KT-----------
----------------------------------------GGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARK
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKVNCANIDGTL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLKSYGAIETDNRDE
RDAIV-NEKIPA--VQSKRHKQ---CFCDDGKT-IDSPFLSH--QERSSESLSVHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLNIKEIMDNVLAKQKAERDD---LAKKY-R
ISIESFKHGALREQLANLVARQKSLLVVAKKQKRISLKIQNYKNVTSLPCLSLRKFPPRS
ENCSEKDNQ-ELTSLENLEHPQSG-----LLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDVNSKQNVS------------DCTLDGFP
KSQHSDGTENNKLPSQPVAFIGQTEYSQKEKEN-DLTEATDKDHEF--C-IPSPVIGKLN
ISATASVLAENSAHPSNIICDQDLSNYHPK-RGNRKTTSRQSPTGASESL-----AHQGV
A-V-LG-SDTVHPMKPCRK-KSVSAVPRADDSQISSSSGSGQQD-IIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKSPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFGQGTSRELMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFYVGCEEL
TL----

MEKGAEASDCDSDETVIEGSVTENEPEDEELPWRRLLLNQDTTCRSEFCFHSGVNGMQKG
-MHSPEIQLGLKL--KKDSQEQNNKNKLLLALSEDLVLQDPRDKT--ARNRVLLQTTKEF
PAFTVSFPHPEVSWSH-----------QNTGGHEA---------ENCENLLHSKKNIEDP
KPFKLQT--------------------------LTDENAI--------------------
--S------------------------------------------------Y--------
--------------------EQI------------------NK--KK-------------
----------------------------------N-SDPMKNTST---------------
---------------------------------QETPHVLRRSSR--LEKLKASRDV--V
HTEAVLK----KPERILSKALSFKDQINSIFTTDSFSKR----------K----NMHSSR
------FKNE--QIRKSEQLRKKNETGEMEKMCL

PF12796 // ENSGT00760000119090_5_Domain_0 (575, 652)

CTINRRNIFGE---NLLYKAALHNDV
DLVRCCIKNGGSVNQPSYA---GWTALHEASVGGYYQAVSELLKGGADVNVKGKYQITPL
HDAVMNRHYKVAELLLMSGADPLFRSDHGTCALDEAKDS-FMENLLMKYIPQQKKCHLSA
QRNSTDPAHVEDMFQNKKPKLSSNNYTEFICDENFNRQEPGHLEINKGSNNLLMS---EE
YVCEHCQKDYNTTTFGKS-------------------NLNSVKNSRTNV-SKRKGQRNRQ
QKKTQVDD-RD---CNLSQKIGTSSFRRTSKLLTQQQHAVQTLSDLPEESFELSTTTLSS
L---ENGIGY-NEACLVSKTSD-----------------T-HVLDSSDGQE-----LESI
DQTEAASVSELPSYKEIKLLPVTTDQQPHTNQEQ-YNSPYKSLGNNSSNEKVKA-INKWE
DSFFSFIKGRSADS-----DSDCHTLDKSIASPK-----EGMSHDHHEEI-MTGQEVDSQ
QCLSSEN-YFSQENDLKVHSLTTHPQEEAVNFCDSN--LISVQHTPDYKNCFHEISFDNS
YAKTEQSSTSCTRPP-STQKVSPLTVEVELLKGLQDSLAHRDSSPLVNQAGIHSVEK---
---KQDTDKNYTKKGPNTSSSTSPLPTVAHSQVIEITKAETRREDLPGNEPINNTDFYST
D-INKELANS-SQLNQGKEKEIV------------------------RKSDVELTHNDSE
AERTFKSCEEKKKNMDSETHSPCNIQEHRKDQ-NFR-KRKCSLKAPCSQGV---------
------------------------------------N--TTGISKRNNKGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHVAARG
GNLSQVKVLIEARADVNLRDNAGWT--PLHKAASGGFDDIIIELLQAGANVNCENIDGIV
PLHGASAGNHLKAAEILLEHGANPNKKDEKQRTALDEADDEKMKELLKSYGAIESTDGEK
RNSTD-LVKIPT--VQPKRYKQ---FICDNDKA-IGSPVPSH--KVKKSESLPAHQTISA
ILQDIGEKQENLLKLEIRNSEDEEQYIGKMLEIKEVMDNILAQQKTERDD---LAKKY-R
VSMESFKHGALREQLANLATRQKSLLVVAKKQKKIRLKIQNYKNATPVSGVGLGKLPCNS
DISSDKKSQ-EPPTMGDSAHAPSGLFAPVSLA-----YRSM-----------QELPLSPE
TESESQKIN-ICLNA-----EATRREEFSGNDINSKQNVQ------------DCALGGLL
RSKPTDDAEKITSSSQPTALTPHEENSHA--EN-IFTETTVKGYGF--D-S-SALTGTIN
ISEDKSIFSPNDACLAAVPHRQELSRCNRK-RRNKKTASQQPSEGAAEPL-----PQ-AT
A-V-LD-TYTVHQTMPCLR-DSAAAASHADSTQSSLSSASAHQH-PTKTVPHHNTTPRKK
AVQLKDLILRGRISPGNNILEFKTQ-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

MEEGVQDPDWDSDETVIEGSVTESDLEEKELRWRRLLFDQDTALKSEFSLHPDTRGMCEG
-MPSPEIQLGFKL--KEDLQEQMSKNRMMPILSEDTILQS-QDET--ERNQALLQTRKNC
SMFIGSFHQSGLSLNH-----------QNSEGPEADETP-----EV---LPHIEKELSDG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAAPNTFYEPRK-EVILTVTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------FELVSDFDSKELMDPLSDSLS
SISI-PLNAWSACH-----RDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EVKFNTSQ-TNEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCEPLSNKRNSHSVTN----SSDQETVCVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDSKEK----NMHSRR
------FKNGK-QIRKNEQFPG---KKEKMKVNKISLGSINRRNIFGENLVYKAALNDDA
DLVHHCIKKGGNVNQPSYA---GWTALHEASVGGFYRTASELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 686)

ITPL
HDAVVNGHYKVAELLLLNGADPLFR

ENSGT00760000119090_5_Linker_1_3 (686, 1434)

NDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEHYQKDPQNTKFGKSKHKQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCVLETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKETH-----------------I-QNLDLSDSQEVQCLELESI
DQTEVVSFPGLSLHKEITLPLVTTDKQPHTLQEQ-HHVLYKSYENSNLVQKDER-FNKWE
NSFLSFVKGNSDND-----DDDCCTSEKAITSKKVMCSTGCKKHCNFKENLTNRREKDFQ
QFLVSED-HFSQENELQAVSLTTLPEQEAVNFSHSDNAVISE-HVANYEQCIFGPSFDHS
HGNPEQNSLACMRTL-STHEVSKLTNHVELFKKPQDY-IPREPTFLMKQADTHIVEEVA-
--KNCDAERNYTDRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPDEELTDNISG
DGITIRNFEEIKEKTKSEMHMPANSQEHKTVQ-NFG-KKQSFLKTTCNL-----------
----------------------------------------CGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARK
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIIVELLKAGAKINCANIDGTL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLKSYGAIETDNRDE
RDAIV-NEKIPA--VQSKRHKQ---CFCDDGKT-IDSPFLSH--QERSSESLSVHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLNIKEIMDNVLAKQKAERDD---LAKKY-R
ISIESFKHGALREQLANLVARQKSLLVVAKKQKRISLKIQNYKNVTSLPCLSLRKFPPRS
ENCSEKDNQ-ELTSLENLEHPQSG-----LLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDVNSKQNVS------------DCTLDGFP
KSQHSDGTENNKLPSQPVAFIGQTEYSQKEKEN-DLTEATDKDHEF--C-IPSPVIGKLN
ISETASVLAENSAHPSNIICDQDLSNYHPK-RGNRKTASRQSPTGASESL-----AHQGV
A-V-LG-SDTVHLMKPCRK-KSVSAVPRADDSQISSSSGSGQQD-IIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKSPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFGQGTSRELMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFYVGCEEL
TL----

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---------------FFFFPFL

PF00023 // ENSGT00760000119090_5_Domain_3 (1463, 1495)

GWT--PLHEASSEGSNDIIVELLKAGANVNCE

ENSGT00760000119090_5_Linker_3_4 (1495, 1497)

NL

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1528)

DGID
PLHDAAANNHLKAAEILLQHGANPNQRNQKQKTALDEADDEKMKELLKSYGAIETDNCDE
SNVIA-TGMYVS--IA--ILD-----------K--YIPLLRK--I---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------

-----------------------------------LLFDQDASLRSELSLHPDISGMCKG
-VPSPEIKLEFKL--SEDPQEQMNKNKMMPVLSEDTILQP-QDET--EQNQALLLTRKIF
PVFTESFPQTGLSINH-----------QNIGGPET---------ENSEVLPHLGKELGED
TDSPEVSLLSGTVITVSDMIAIKEKSLIEPEKILAAPDTFSEPGK-EVTLTMSSEETKVE
ESSLETFVSALERLLTSPESSQEERL-------------FEIVKDFDPKDLMNPLSDSLS
STSV-PLDALSACH-----RDLLENTK-DDTLPVELLA-ALNTLSEANVESICHGKERDN
SLITG----NEC--L------------EVEFNISQ-NNEDLTQIA-----ETLEDPNPSG
SQTLAYQNVTSFEPLNKKGNSNSVKN----SSDQETARVLRRSSR--LEKLKVSRDANGK
YTGDMCK----MPEKILPKIPNCEDLINNNSSAENFRMQDPTLMTEGKER----TMH--S
------FKSGE-HIRKSKQLRG---KREKMKMNKTSLSGINRRNVFGENL

PF12796 // ENSGT00760000119090_5_Domain_0 (591, 682)

LYRAALHDDA
DLVHHCIKSGGNVNQPSYA---GWTALHEASVGGFYQTASELLKGGADVNFKGMYQITPL
YDAVLHGHYKVAELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLYRGDNGKCALDEAKDS-RMKHLLERYVSKHKKYLTSA
QKNSANPLDTEDVHQHKKPKFSSENCILCVGDEHSNRQKPEHVKVNNTSKESLFIN---E
DVYECCQGDSQSTKFSKSMHKQSTLNQIHST-GLRKGNVHNIKDPNTNV-PRGSR-RKTQ
PKRPQGDD-GD---CNSRRSVAVSSSRRVNRVVTRQQHILQTLDDLPEVSCEPSSPTLSN
L---KNGLDNNIKPCSVSKETH-----------------T-QSLDLSNGQEAQFL--ESI
DQTEAAAFSGSSLHEKINLLFVTTDKQPHTLQEQ-LSSPYKPHENSNSVQKDKS-LNKWE
ISFLSFIKRNCDVD----DDGDCSSSEKVVTSKKIVCSTDCKDHYNYKDNITNRKDNDFQ
QYLPSEG-SFLQENESKAGSPTTFPQQEAVSFSDPENAVISGQHVANCEQCISGTSFDHS
HGSPEQTSMACMRIL-STPEFSELTSHVELFRKPQDH-SPRTPTCLINQTDTRTVEKVT-
--KKQDTKKNYTDKGQKISSSAGPLSTAVHSKVIETTEVEKRRQNLPESGTIHTIDFHPI
DNMNEELTNVSQL-SPREEKEIS------------------------HKPDEELTNNING
EKNTIRNCEEKK-KTESEIHMPTNIQGHKKAQ-NVR-KRQSFLKATCNQGM---------
------------------------------------K--TAGVNKRNARGESK

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLLKTLIESGADVNLKDNAGWT--PLHEASIEGSNDIIVELLKAGANVNCENLDGIL
PLHDAVANNHLQAAETLLKNGANPNQKDQKQKAALDETDDEKMKELLKSYGAIETNIRDE
SNAIV-NVKIPA--VHSKRHEQ---CFCDDGKT-VDLPSLSH--QEEIREDLPVHQSLSA
IVQDIEEKQENLLEFEIRNPEDAEQYIAKMLRIKEVMDGVLAKQKAERDD---LAKKY-R
VSIESFKHGPLREQLANLATRQKSLLVVAKKQKKISLKIQNYKSATTLSGVSLRKLPPRT
EMSSEKNSQ-KLISLENSMQPQLD-----SLSPVNLDCENT-----------QETQLSLE
TWNDRQSTN-ICLSS-----EAVRREEFSGNELSCKQNVS------------DCPLDWLS
KSRHSDGAEKIKLPPQPVAFIAQTEYSQK--EN-DLTEITAKEHDF--Y-SPSPVTGTLN
ISETISVPAPNNAHPSTVIYDEDLSNYEPK-RRNRKTTSQKPPAETSESL-----EHQRI
A-V-GG-SDTEYQIKPYLK-KSASAIPHTNDSQISSSSGPGCQH-TTKKSLNCSTAPKKK
RMQIKDLILLGRLNPGSNILEFKTQETTHKASILLNGKIKVENGQIYQNPVTWLRDILGG
NSCVTWNYAWSKVTYLGKELLKYVSEEAPMLPEPNLVL-QHRPCLPEVPCL-DDPV--QE
PSKSMFEKMKFGQGASRESRQSIPDYLQ-INEILLISDQEFLPCHIMDQHWKFYVECEEL
TF----

MEEGLQDPDWDSDETVIEGSVTESDLEEKELRWRRLLFDQDTALKSEFSLHPDTRGMCKG
-VPSPEIQLRFKL--KEDLQEQMSNNRMMRILSEDTILQS-QDET--ERNQALLQTRKNC
SMFIGLFRQSGLSLNH-----------QNSEGPEADENP-----EV---LPHIEKELSEG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAARNTFFEPRK-EVILTMTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------SELVSDFDGKELMDPLSDSLS
SISI-PLNAWSACH-----RDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EV-FNTSQ-TNEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCESLSNKRNSHSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEK----NMHSPR
------FKNGK-QIRKNEQFPG---KKEKMKLNKISLGSINRRNIFGENLVYKAALNDDA
DLVHHCIKKGGNVNQPSYA---GWTALHEASVGGFYRTASELLKGGADVNIKGMYQ

PF00023 // ENSGT00760000119090_5_Domain_1 (657, 685)

ITPL
HDAVMNGHYKVAELLLLNGADPLF

ENSGT00760000119090_5_Linker_1_3 (685, 1434)

RNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDTEDVYQHKKPKFSSKSHIWHVCNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEYYQKDPQNTKFGKSKHTQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRRKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCILETLNDLPEESCEPSSLTLSS
L---KNGLNNSTEACSVSKETH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLSLHKEITLPLVTTDKQPHTLQEQ-HHVLYKSYENSNLVQKDER-FNKWE
NSFLSFVKGNSDND-----DDDCCTSEKAITSKKVMCSTGCKKHCNFKESLTNRKEKDFQ
QFLVSED-HFSQENELQAVSLTTLPEQEAVNFSHSDNAVISE-HVANYEQCIFGPSFDHS
HGNPEQNSLAYVRTL-PTHEVSKLTNHVELFKKSQDY-IPREPTFLMKQADTHIVEEVA-
--KNCDTERNYTDRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETVHEIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPDEELTNNISG
DGITIRNCEEIKEKTESEMHMPANSQEHKTVQ-NFG-KKQSFLKTTCNLGM---------
------------------------------------K--TGGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAART
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIVVELLKAGAKVNCANIDGTL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLKSYGAIETDNGDE
RDAIV-NEKIPA--VRSERHKQ---CFCDDGKT-IDSPFLSH--QERSSESLSVHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLNIKEIMDNVLAKQKAERDD---LAKKY-R
ISIESFKHGALREQLANLVARQKSLLVVAKKQKKISLKIQNYKNVTSLPCLSLRQLPPRS
ENCSEKDSQ-ELTSLENLEHPQSG-----LLSP---VCGSM-----------QETQLSLE
TWNCSQNTN-ICLNS-----EAVRRGEFSGNDVNSKQNVS------------DCTLDGFP
KSRHSDGTENNKLPSQPVAFIGQTEYSQKEKEN-DLTEATDKDHEF--C-IPSPVIGKLN
ISETASVLAENAAHPSNIICDQDLSNYHPK-RGNRRTTSRQSPTGASESL-----AHQGV
A-V-LG-SDTVHPMKPYRK-KSVSAVPRADDSQISSSSGSGQQD-TIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKNLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPVLPEPNSVPQQYQPCLPEVACLDDPA---QE
PSKSMFEKTKFGEGTSREPMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFYVGCEEL
TL----

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------ELSVG
VDSPETSLLSGAITTSYNAVEVKKKSSEKLEGSSLLPQFLKEVSL-P------SR-EIRE
DCSCEILVPTIEDTLGFSESILGE-Y-------------PFIVNEFETKELLKPLSDLGS
PKSMSPLDHLLICQEDGLTEDMQENDK-NDALPAELLT-ALNTLSESMVESICQRVERDS
RPCAE----DEC--L------------ETEPSFSQ-TDDDCTQIA-----ADKEYTSSFG
QETLAHQNVACFDALSKEGNLNTMEN----NT--ETSYMLRRSAR--LKTVRAGTTS--K
NIDEAYK----VPEEILQKTDST-------LPIEYFRIQDSAFQNTSDEK----SVEWSK
NQFLSAYNCDE-EEIIKSRRTT---KNRKSHRNISKLSSINRRDIYGESPLHKAAQGDDS
ALVKKYIKLGGNINLPDYAGTI

PF00023 // ENSGT00760000119090_5_Domain_0 (623, 652)

GWTALHEASVNGFYKTVLELLKGGADVNCKGMKQITPI
YDAVLNGHYKVAELLLQNGADPLFRNDYGKCALDEASDNTHMKQLLERYVHKSE------
------------------------------------------------------------
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------

MEEGVQAPNWDSDETVIDDSVTESDLEEEELPWRRLLFDQDTSLRSEFSLHTDRRGMCKG
-MPSPEIQLGFKI--REDLQEQMNKNKVVPVLSKDTILQS-QDET--VQNQALLQTRKNC
SLFVGSFPQSGLSSNH-----------QNIEEPEP-ESP-----EV---LPHMEKELSEG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKTLAEPNTFFEPRK-EVTLTMTSEETKDE
ESSLETFVSALERSLTSPESAQEERL-------------FELVSDFDPKELVNPLSDSLS
SISI-HLNAWSSGH-----RDLQENVK-DDALPAELLE-DLNTLSEAKVETICHRKEGGS
SLSAG----NEC--L------------EVEFSMSQ-TNEDCTQIA-----ETLQDPNPSG
LQTLAHQNITSCEPLSNNRNSNSVTN----SSDQETACVLRRSSR--LEKLKISKDA--K
YSDHMYK----MPEKILPKILGCEDLTDNNSSTQNFRLQDPALMTDGKEK----NIHSAR
------FKNGE-QIRKNEQFSG---RKEKMKVK

PF12796 // ENSGT00760000119090_5_Domain_0 (574, 652)

KILIASINRRNSFGENLVYQAALHDDA
DLVRHYIKQGGNVNQPSYA---GWTALHEASVGGFYRTASELLKGGADVNIKGMYQITPL
HDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKNS-CMKRLLERYIPKHQKCLTLA
QRNSIDPLDIEDVYQHKKPKFSSKSHICHVCNENCNRQKQEHVKVNKENKESLFTNINKE
DVYEYYKKDSKNTKFGKSKHKQSTLNQIYST-GLRKCSIYNVKDSKTNV-PKGIGRRNTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTDQQHIPQTLSDLPEESCEPSSITLPS
L---KNGLDNNIEVCSVSKETH-----------------I-QNLDLSESQEVQCLELESV
DQTEAVSFPGLSLHKEINLPLVTTDKQPHTLQEQ-HHFLYKSHENSKLVQKDES-FNKWE
KAFLSFVKGNSDND-----DDDFSNSEKAVISKKVTCSTGCKNHYNFKENLTNRKEMDFQ
QFLLSED-HFSQENEVKAVSLTTLPEQEAVNFSDSDNVVISEQHVANCEQCIFGPSFDHS
HGNPEQNSLACMRTL-STQEVSKLTNHVELFKKPQDC-IPRAPTFLMNQTDTHIVEEVA-
--KNCDTERNYIDSEQKLSYSNEPLFIVVHSQVIETTKAEKRRQN-LESETVCDIDSHST
DNMNKDLTNISQL-SQREKKEIS------------------------YKPDEELTNNISG
DEITARNCEETKEKTESEIHMPTNIQEHKTVQ-NFR-KRRSFLKTTCK-GM---------
------------------------------------K--TGGINKRNARGKSR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLVKALIESGADVNLNDNAGWT--PLHEASSKGSVDIIVELLKAGANVNCENIDGIL
PLHDAVANNHLKAAEILLQNGANPNQKDK-QKSALDEADDEKMKELLKSYGAIQTNNRDE
SDGIV-NEKIPA--VRSKRHKQ---CFCDDGKP-VDSPSLSY--QERSRESLSSHQTLSA
ILQDIEEKQENLLEFEIRNPEDAEQYIEKMLKIKEIMGNVLAKQKAERDD---LAKKY-R
VSIESFKHGALREQLANLATRQKSLLAVAKKQKKISLKIQNYKNVTSLSCLSLRKLPPRS
EIFSEKDSQ-ELTSLENLEHPQSV-----SLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVIRGEFSGNEMNSKQNIS------------DCTLDGLS
KSRHSDGTKKIKLSSHPVAFIGQTEYSQK--EN-DLIYATDKDHEF--Y-SPSPVIGKLN
ISETASILAKSGAHPSNVICDQDLSNYDPK-RGNRKTTSQEPPRGTSESL-----AHQGI
A-A-SG-SDTVNQMKPYVK-KSVSAVPHADDSQISSSSRSGQQY-TIKKLLSYSTAPKKK
CVQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGHIYKNPVTWLKDLLGG
NSYVTWNYAWNKVTYLGKELVKYVSEDVSLLPEPNSVPQQYQPCLPEVACLDEPV---QE
PSKSMFEKTKFEQGTSREPMQSIPRYLQ-INEILLISNQEFLPCHIMDQHWKFYVECEEL
TL----

MEKGAQASECDSDETVIEGSVTENELEDEELPWRRLLLNRDPSFKSEFCLHSGENGMWKG
-MPSPEIQLGLKFLSRKDSEEQKNKNKVMPTLSEDLVLQDPQDEA--TQNQILLQL-KEF
PAFSLPSPHPEFSWSH-----------QKTGGPEA---------ENGEYLPHPGKELSEN
TDSPEISLLSGTSLMASDLVTPKEKSFAKPVKTLAVPNTFFEPEQ-EVTLTMTSKETKDE
ESSLETFVSALERLLESPEGTQEETL-------------LEIANDFNPQELKNPLSNSLS
SVSV-PLNDLSACC-----RDVLENTKNGDALPAELLA-TINM----LPGPICQGQEKSS
SVSGG----NGC--L------------EVQPTMSQ-IDEDCTQIV---------------
---------------------------------QETPHVLRRSSR--LEKLKASRDV--A
HTDV-LK----MPESISSKPLSCEDQIHNIFTD---SKR----------K----NMHLSR
------FKSE--QRKNNE

PF12796 // ENSGT00760000119090_5_Domain_0 (559, 685)

QLKIK-------------------------------------
------------------N---GWTALHEASVGGYYQTVSALLEGGAEVNVKGKYQITPL
HDAVMNGHYQVAELLLLNGADPLL

ENSGT00760000119090_5_Linker_0_3 (685, 1434)

KSDRGTCALDEAKDS-FMENLLRKYIPKHKNHHLSA
QRKSTDPAYVDDIFQYKKPKLSSNNHTEFICSENSNRQEPEHVEINKERNNLPVN---KE
YVYEHCQKN--TIEFGNS-------------------KVHSVKDSRTNV-SKSKRGRNTQ
HEKTQTDD-RD---CSLSQGTAISSSRGMDKFLTQQQHIALTLDDLPKESCELSTPALPS
L---KNDADNNNEACLNSKKPN-----------------T-SNLDLSDSQEMQFLE--SI
DQTKAVSFSELSLYKEIKLPHVTADQQPHTNREQ-CSSPCKPPENHSSDEKGKN-LNEWE
DSFLSFIKGGFADS-----DGDCHNSVKSAASQE-----ECMAVCHNEETTTDGEKMNSR
LFLSSEN-YSLQENELKAGSQTTYPQEKAVNYCDLNDTLIYKQPIPNHKQCTYGISFDYS
YAISEHNYTSCTRSP-SKQQVSQLTGQVELLKVFQDN-SHSEPTLLVNQVNTYNVEK---
---KQDTKRNYTIEGQKPSSSHSPLHT--HSQVIEVTKAEERSQDLPENELVSNTDFHST
DNMNKELTNS-IHLDQGEEKEIA------------------------HKSDEELTTNTSR
AERTVRNCREEKENVGSATQMPCDTQDHGRDQ-NFR-ERKGSLKAPCSQEV---------
------------------------------------N--TAGIRKRNAKGESL

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHVASRG
GDLSLVKVLIASGADVNLKDNTGWT--PLHEASSAGFNDVIIELLKAGANVNCENVDGMP
PLHGAAVGNHLKAAETLLEHGANPNQKDQKQRTALEEADDEKMKDLLRSYGAVETSNGDE
VGSTV-PVKHPA--LRPKRCKP---CPCDDGKT-IAPPSPLR--KAKRSENLPAHQTISA
ILQDIEEKQENLLKLEIRDSEDAEQYIGKMLEIKEIMDDILAQQKTERDD---LAKKY-R
VSMESFKHGALREQLSNLATRQKKLLVVAKKQKKIRLKIQNYKNSKPLSGIK--KRTCSS
DISSEKKSQ-ESPSMKNSAYPQSDLLSPVSLSAISPVNRNM-----------EEIPLSME
MKK-----------------------ELSGNEMNSKQNVQ------------DCALDGLL
KSRLTDGTEKTGLSSQPVAFVPQAGNSQA--E-----KTLVKGYEP--D-GSPAVTGTLS
ISEDKSVLSQNDACPPAVPQNLDLSRCNPK-RRNKKTASNQPSVGTSEPL-----AHQAV
T-V-LD-TDTVQRV---------------NSVPIPPSSGSVRQQ-PIKKPPHHSTAPKKK
NMQLKDLLVRGRINTGKDILEFKTQETTHKASILLSGKLKVENGQIYQNPVTWLKDLLGG
GNYVTWNYAWSKVTYLGKELLKYVSEEEPVPPEPCNTPQQQQPCLP--------------
-------------GTSGKSVQSFPHYLQ-IKEILAISDQELLPSHVMEQHWKFYVECKTR
G---SW

------------------------------------------------------------
---------------------------------------S-QDET--ERN----------
----------------------------QALLPEADETP-----EV---LPHIEKELSEG
RDSPEVSLLSGTAITVSDMVAVKETSLIEPEKILAAPNTFFEPRK-EVILTMTPEETKDE
ESSLETFVSALERLLTSPESTQEERL-------------SELVSDFDRKELMDPLSDSLS
SISI-PLNAWSACH-----RDSLENAK-DDALPAELLE-ALNTLSEAKMETICHRKEGGS
SLIAR----NEC--L------------EVKFNTSQ-TSEDCTQIA-----ETLQDPDPSG
LQTLAHQNITSCEPLRNKRNSHSVTN----SSDQETACVLRRSSR--LEKLKVSRDA--K
YSDHMYK----MPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEK----NMHSPR
------FKNGK-QIRKNEQFPG---KKEKMKVNKISLGSINRRNIFGENLVYKAALNDDA
DLVHHCIKKGGNVNQPSYA---

PF00023 // ENSGT00760000119090_5_Domain_0 (623, 652)

GWTALHEASVGGFYRTASELLKGGADVNIKGVYQITPL
HDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDL-CMKRLLERYIPKHQKCLTSA
QRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKESLFI--NKE
DVYEYYQKDPQNTKFGKSKHTQSTLNQIYST-GLRKGNLHNVKDPNTNV-PKGIGRKKTQ
RKRTQVDD-VD---CNPRKTLAVSPSRRINRLVTYQQCILETLNDLPEESCEPSSLTLSS
L---KNGLDNSTEACSVSKETH-----------------I-QNLDLSDSQEVQCLELESV
DQTEAVSFPGLSLHKEITLPLVTTDKQPHALQEQ-HHVLYKSYENSNLVQKDER-FNKWE
NSFLSFVKGNSDND-----DDDCCTSEKAITSKKVMCSTGCKKHCNFKESLTNRKEKDFQ
QFLVSED-HFSQENELQAVSLTTLPEQEAVNFSHSDNAVVSE-HVANYEQCIFGPSFDHS
HGNPEQNSLACMRTL-PTHEVSKLTNHVELFKKPQDY-IPREPTFLMKQADTHIVEEVA-
--KNCDTERNYADRDKKIIYSNEPLSIVVHSQVIETTKVEKRRQNHLESETIHDIDSHST
DNMNKELANISQL-SQREKKEIS------------------------HKPDEELTNNISG
DGITIRNCEEIKEKTESEMHMPANSQEHKTVQ-NFG-KKQSFLKTTCNLGM---------
------------------------------------K--TGGINKRNARGESR

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSLVKALIESGADVNLNDNAGWT--PLHEASNEGSIDIVVELLKAGAKVNCANVDGTL
PLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLKSYGAIETDNRDE
RDAIV-NEKIPA--VRSERHKQ---CFCDDGKT-IDSPFLSH--QERSSESLSVHQTLSA
ILQDTEEKQENLLEFEIRNPEDAEQYIEKMLNIKEIMDNVLAKQKAERDD---LAKKY-R
ISIESFKHGALREQLANLVARQKSLLVVAKKQKKISQKIQNYKNVTSLPCFSLRQLPPRS
ENCSEKDSQ-ELTSLENLEHPQSG-----LLSP---VCGSM-----------QETQLSLE
TWNYSQNTN-ICLNS-----EAVRRGEFSGNDVNSKQNVS------------DCTLDGFP
KSRHSDGTENNKLPSQPVAFIGQTEYSQKEKEN-DLTEATDKDHES--C-IPSPVIGKLN
ISETASVLAENAAHPSNIICDQDLSNYHPK-RGNRKTTSQQSPTGASESL-----AHQGV
A-V-LG-SDTVHPMKPYRK-KSVSAVPRADDSQIFSSSGSGQQD-TIKKPLNYSTAPKKK
CIQIKDLILLGRINPGNNILEFKTEETTHKASILLNGKLKVESGRIYKNPVTWLKDLLGG
NSYVTWNYAWSKVTYLGKELLKYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPV---QE
PSKSMFEKTKFGEGTSREPMQSIPRYLQ-INEILLISDQEFLPCHVMDQHWKFYVGCEEL
TL----

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---------------------------------------PSGL-PGNFTEV---------
------------------------------------K--TTGIDKRNA

PF00023 // ENSGT00760000119090_5_Domain_2 (1429, 1461)

KGESRLHLAARR
GNLSLVKALIESGAYVNLKD

ENSGT00760000119090_5_Linker_2_3 (1461, 1462)

N

PF00023 // ENSGT00760000119090_5_Domain_3 (1462, 1496)

AGWT--PLHEASSEGFSDIVVELLKAGANVNSEN

ENSGT00760000119090_5_Linker_3_4 (1496, 1497)

L

PF00023 // ENSGT00760000119090_5_Domain_4 (1497, 1513)

DGIL
PLHDAVINNHLKV-----------------------------------------------
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------

MESGAQASDCDSDETVIEGSVTENELEDEELPWRRLVLNQDTSLKSEFCFHSGVNGMWKE
-MPSPVIQLGLKF--RKDSEEQKNKNEEMPTLSEDRVLQDFQDEA--TQNQVLLQTRKES
PAFSVLFPHPEVSWSH-----------RKTGGPEV---------ENCENLPHPEKELSKN
TDFPEISLLSGTSLMTSDLVTLKEKSL-EPVKTLAVPSTFSDTGK-EVSLIMTSKETKDE
ESSLETFVSALERLLESPDGTQEET--------------LEIVNDFNLQELTNPLSSSLS
SVSV-PLNALPTCY-----RDALENKKDHDALPAELLG-AINA----LPGPICQGQEKNS
SVSDG----NGC--L------------EVQPTMSH-IDEDCTQIA---------------
---------------------------------QETPHVLRRSAR--LQKLKASRAV--T
HTDVTLK----IPEETLSKLFSYEDSICSIHATENFSKR----------K----NIHSSR
------FKSE--QIQKNEQLKIK-------------------------------------
------------------D---GETYFEYFFI--YFIPFSGLCRH--------------H
THKSTDIHAGVAELLLLNGADPLFVSDHGICALDEAQDS-FMENLLRKFIPKHKKCHLSD
QRRSTDAANAEDIFQYKVYLYLV------------------INIFA-GLYLLVIF---ID
YQRE--RKTDSTDLRT-N-------------------SAHSLKDSRTDV-SKSKAPRNAQ
HKKTQVDD-KD---YNLSQGTAVSSFSRMNTLVTLQQHTVQTLDDIPKESCELSVSIPAS
L---NNGSGNSNEACFVSKKSN-----------------T-HILDLSDSQEMQFLELGSI
DQTKAASFSERPLCKEIKLPHVTADQQPHTNQEQ-HSSPCNPPENKSSDEKGKN-FNKWE
DSFLSFIKEGFADS-----DSDCHTSVKSVASQK-----ECMGHCHNEASTAEGEEMDSL
QVSSSEN-YFSQENELKAGSLTTCPQKEAVNYCDSKKTSIYEQHIPNYEQYIHGIAFDHS
CANSEDYLMPCTGPP-STHEVTQVTGQVELLKAFQNN-AHREPTPLVNKADTYNVEK---
---KQDTEKNYVVKDQNPSSSNSPLHTVVHSQVIEITTAEKRTQDLPGNKPVDNTHFHSI
DNVNKELANS-SQLNQGEEKEIA------------------------HKSDEELTDNTST
AERTVRNCKEKGETVDSETHMPGDTQEHRQDQ-NFR-KRKGSLEAPCSQG----------
------------------------------------F--TDGIKKRNAKGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLASRE
GNLSLVKVLIESGADVNLKDNAGWT--ALHEASSEGFSDVIRELLEAGAHVNCESMDGTL
PLHAAAAGNRLKAAEILLERGANPNQKNQKQRTALEEADDEKMKELLKSYGAVETSNGNE
ISSAV-TVKHPA--VRTKRYKS---CSCDDEKT-IDPPSPLH--KVKRSESLPAHQTVSA
ILQDIEEKQENLLKFEIRNSEDAEQYIGRMLEIKEVMDNILAQQKTERDD---LAKKY-R
VSVESFKHGALREQLANLATRQKSLLVVAKKQKKIRLKIQNYKNAKPFSGISLRKLPSSS
DISSK-KSQ-ESPGVEKPAHPQSGSLSPVCLASISPVSRST-----------------VE
IQKDSQNSN-ICLDA-----EAMERGGFSGNEMNSKENVQ------------GCTLDGLL
SSRYSVGTEKIKISSKPVAFIPQGGNSQE--E-----KTIVRGYSL--D-SSPAVTGTVN
ISEDKRVFSQNDACLPTVRQNQDLSRCYPK-RSNKKTASQTPSGGASEPL-----ARQVT
T-V-LD-TDTVQQTKPCPK-KTASVNAHENSLQISPSSGSANQH-SIKTPSRHSTTAKKK
NMRLKDLILLGRINPGNNILEFKTQETTHKASVLLSGKLKVENGQIYQNPVSWLKDLLGG
GNYVTWNYAWSKVTYLGKELLKYVS-EVPVSPEPHNTPQQQQPCPP--------------
-------------GTPRKSMQSIPHYLQ-IKEILLISDQELLPCHVMEHHWKFYVNS-LF
S-----

MEKGAQASDSDSDETVIEGSVTENELEEEELPWRRLLLNRYTSSKSEFFLHPGVNGMWKG
-MPSPEIHLGLKL--GKDSQEQKNKNKVMPTLSEDLVLQDPQDEA--TQNQVLLQTRKKS
SAFSVSFPDPEVSCSH-----------QKTGGPDS---------ENCENVPHSEKELSEN
TDSPETSLLSGTSLMASELVTLKERSLAEPVKTLAVPNTFSEPGK-DVTLTMTSKETKDE
ESSLETFVSALERLIESPEGTQEETL-------------LEIMNDFDPQELMNPLSNSLS
SLSV-PLNALSASY-----RDVLEITKDEAALPAELLA-TINT----LLGPICQGQEKSS
SASDG----NGC--L------------EVQSTMSQ-IDEDCTQIA---------------
---------------------------------QEPPHVLRRSSR--LEKLKASRAV--T
HTDVVLK----TPETILPKPLSYEDQIDSIFATES--SR----------K----NMLSSR
------FKSE--QIRKNEQL

PF12796 // ENSGT00760000119090_5_Domain_0 (561, 682)

KIK-------------------------------------
------------------N---GWTALHEASLEGHYEIVSELLKGGADVDVKGKYQITPL
HDAVMNGHYKVAELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFTSDHGICALDEAKDS-AMEKLLRKYIPKHKKSAQRK
---NTDPAYVEDIFQYKKPKLSSANHTEFICDENSNRQEPGHVEMK-GSNNLLIN---EA
YICEPCQKNSNTTEFGKN-------------------NVHNVKDSRTNV-SENKGQRNTQ
HTKTQVDD-RD---CNLSQGIAISSFRRMNKLVTPQQRTIQTLDDLSKGSCELSTPTLAT
L---KNGAGSNSETCVVSKKAN-----------------T-HILDLSDSQEMQFLELESI
DQTKHASFSELSLYKEIKLPHLTADQQPYTNQE--------SPENKSSDEKGKN-LNEWE
DSFLSFIKGRFADS-----DSDCHTSNKSVESQK-----EFVGHSPNEESTANKEEINAL
QCLSSEN-YFSRENELTMGSLTTHPQKEAVNYCDLNNPLIYEQHIPNDEQYIHGISFDHS
YASNEHNSMPCIKLP-STQNVSQLTSQVELLKAFQNN-GHREPTPLVNQTDTYNVEK---
---KQDTERNYTVKSPNPSSSDSPLHTVVHSQVIEITKAEKRRQDLPENESVNNTDFHST
DDVNKELASS-SQPNQGKEKEIA------------------------HKSDEELTNNTSR
AERAVGNCKEKKRNVDSEGHMPCDSQEHIKDQ-NLR-KRKISLKTPCSQEA---------
------------------------------------K--TAGIKKRNAKGESP

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHVASRG
GNLSLVKVLIESRADVNLKDNAGWT--PLHEASSEGFTDVIIELLKAGANVNCESMDGML
PLHGAAAGNHLKAAEILLEHGANPNQKDQKQRTALEEADDEKMKELLKSYGAVETRSGDE
MGSAV-TVKRPA--LRPKRCKP---CTCDDEKT-IDPPSPLH--KAKRSEGLPAHQTISA
ILQDIEEKQENLLKFEIRNSEDAEQYIGKMLEIKEVMDNILAQQKTERDD---LAKKY-R
VSMESFKHGALREQLANLATRQKSLLVVAKKQKKIRLKIQNYKNAMPFSGVSLRKLPCSS
DIASEKKSQ-ESPRLENSVHPQAGPLPPVSLASVS-------------------------
--SDRHDSS-ICLNA-----EAMKRGEFSGNEMNSKQNVQ------------DCVLDGLL
KSRHSDGTEKMKSSSQPVAFIPQAGNSQA--E-----K----SYGL--D-SSPAVTDTIN
ISEDKSVFSQNDARPPPGPQNQDLSCCTPK-RRNKKPVSRQPSGGASEPL-----AHQVT
A-V-LD-TDTVQQTKSCLK-NTASVVSHANSIQNSPSSGSAHPH-SIKKPSHHSTAPKKK
NVQLKDLILLGRINPGNDILEFKTQETTHKASILLSGKLKVENGQIYQNPVSWLKDLLGG
DSYVSWNYAWNKVTYLGKELFKYVSEEVPVPPEPCSTPQQQQPCLP--------------
-------------GTSRKSMQGIPHYLQ-IKDILSISDQELLPCHVMEQYWKIYVEH-LF
S---Q-

MERSAQALDYDSDETVIEGSVTENELEDEELPWRRLLLNRDTSLKSEFCFHSGVNGMWKG
NIPSPVIQLGLKL--GKDSEEQKDKNEVIPTLSEDGVLQDFQDEA--TQNQILLQTRKEF
PAFSVLFPHPEVLWSH-----------QKTRGPEV---------ENCENLPCPEKELSEN
TDSPEISLLSGTSLVASDLVILKEKSLAEPVKTLAVPNTFSETG------------TKDE
ESSLETFVSSLERLLESPEGTQEETL-------------LEIVNNLNPQELMNPLSDSLS
SVSV-PLNALPACY-----RDVLENMKDNDALPAELLA-AINT----LPGPICQGQEKSS
SVSDG----NGC--L------------EVQPTMSQ-IDEDCTQIT---------------
---------------------------------QETPHVLRRSSRLRLKKLKESRAV--A
HTDIMLK----IPEKILSKPLSYEDQTNSIFATENFSKQ----------K----NIHSSR
------FNSE--QIQKNEQL

PF12796 // ENSGT00760000119090_5_Domain_0 (561, 682)

KIK-------------------------------------
------------------N---GWTALHEASVGGFYQTVSELLKGGADVNVKGKYQITPL
HDAVMNGHYKVAELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFRSDHGTCALDEAKDS-FMENLLKKYIPKHKKCHLSG
KIEPLCCRHVETNKEI---------------------------------NNLLVN---KE
YVHEFHQKNSNTKEFG-N-------------------SKPSVNNSRTDV-SKSKGPRNTQ
NKKTQVDD-RD---CNLSQGVAVSSFGRMNKLVTLQQHTVQTLDDLPKESCELSIPIPTS
L---KNGSGNSDEACLISKKAN-----------------T-HILDLSVSQEMQFLELGSI
DQTKAASFSELPLYEEIKLPHVTADQ-PNTNQEQ-CNSPRNPPENNR-SEKGKN-LNEWE
DSFLSFIKGHFADS-----DSDGHTSVKSVASQK-----ECMGHCHNEASTAEGEEMDSL
QVLSSEN-YFSQETEQKAGSLTTYPQEEAVNYCDSNKSLIYEQHFPNYN-CIHGIAFDHS
YANTEYNWMPCTRPP-STQKVTQVTGQVELLKAFQNN-AHREPTPLVNQADTFNVEK---
---KQDTERNYTVKGQKPSPSNSSLHTVVHSQVIEIPTDEKRTQDLPGSKPVNNTDFHST
DNVNKELASSSPQLNEGEEKEIA------------------------HKSDEGLTDNTSR
AERTVRNCKEKGENVDSETHMPSDTQEHRKDQYYFR-KRKGSLEAPCSQG----------
------------------------------------F--TTGIKKRNAKGESQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHVASRE
GNLPLVKVLIQSGAVVNLKDNAGWT--PLHEASSEGFGDVITELLEAGAHVNCESMDGTL
PLHAAAAGSHLKAAEILLEHGANPNQKDQKQRTALEEADDEKMKELLKSYGAVETSNGNE
ISSAV-TVKRPA--IQPKRYKS---HSCDDEKT-IDPPSPLH--KVKSSESLPAHQTISA
ILQDIEEKQEKLLKFEIGNSEDAEQYIGRMLEIKEVMDNILAQQKTERDD---LAKKY-R
VSMESFKHGALREQLANLATRQKSLLVVAKKQKKIRLRIQNYKNTKPFSGFSLRKPPSSS
DVSSEKKNQ-ESSSLENSVHPQSSSLSPVSLTSISPVDRSM-----------EEIPLSVE
IQKDSQKSN-ICLDA-----KAMRKEGFSGNEMNSKENVQ------------GCALDGLL
KSRHSDGTEKIKLSSQPVAFIPQGGNSQA--E-----KTIVKGYRL--D-SSPAVTGTVN
IPEDKRVFSQNDACLPTVPQNQELPR-YPK-RSNKKTASQPPSEEASEPL-----AHQIT
T-V-LD-TDTV-QTKPCPK-KTASVVAHANGLQISPSSGSSYQH-SVKKPSHHSPVSKKK
NVQLKDLILLGRINPGNDILEFKTQETTHKASILLSGKLKVENGKIYQNPVSWLKDLLGG
GNCVTWNYAWSKVTYLGTELLKYVS-EVPVPPEPHSTPQQQQPCLP--------------
-------------GTPRKSMQSIPPYLQ-IKEILLISDQEFLPRHVMEQHWKSHHSEALF
S-----

-EGEAQALDWDSDETVIEGSVTESDPEDEELPWKRLLFDQDISSRSVFSLHPGMNGRCQG
-MLSPEIKLGMKF--RKDLQEQMNKNKMMPILSSDTVLQV------------CYMIKKHF
PGSNLSFFQSGLSLYH-----------QNIGGKVC-------------------------
---PEISLFSSTAITDTDTASVKEKSLIETEKILLAPNISSEPEQEGVTLTVTSKESVDE
ESSVETFVSALEKLLTS-ESIKEERM-------------LEIMKDFDFGELMNSLSDSPS
SISV-PTNAISACC-----RDLLENTK-DDALPTELLA-AINTLSEAKVGSSCHGKEQGG
RF-GG----NEC--F------------EVEPDLSQ-MDEDCTQIT-----EQ--------
----------------------------------ETPCVLRRSSR--LEKLKVSREA--K
HEDTMCK----SSEKIIPKILSSEEQINNKSSTENFSK----------EM----NKHSSR
------LKAE--HIRKNEQLE---------------------------------------
---------------

PF12796 // ENSGT00760000119090_5_Domain_0 (616, 682)

-IKK---GWTALHEASVGGFYQIVSELLKGGADVNTKGMHQITPL
HDAVINGHHKVAELLLLNGAD

ENSGT00760000119090_5_Linker_0_3 (682, 1434)

PLFRSDNGKCPWDEAKDS-RMKHLLEKYIPKDDKCLKSA
HSDGTHRVDVEDVHQHKKPKFSSKTCSESVSNENSNRYKPEHEEVNKERNEGLPI--SNE
DIYERFTNNSTTTNFGRSKPR------------------------HTNV-SKNKERRD-L
YNKTQADD-GD---YNSRQAIAVTSSSIINKSVSHQQHVLQTFNDFPQDSCELFSPTLSS
L---KSVLVSNTEACSASKETH-----------------T-YNLDLSSSQEMKFLELESI
EQTEAVS--ELRSHKEIKLPFVTKDQQIHTHQKQ-HSSPYKSQENSNSVQKNNS-FNKWE
NSFLSFVKAHFDSD-----DSDSSISEKTVTSKKV----EYKNHHNYEETITNSEEMDSQ
PFLPSEG-HVSQENELKAGSLTTLSQQEAVNFCDSDDTVISEQYVVNYEQQLYGISFDHS
YCNREPISMACTRMP-STLEVSNFTCHLEQFKKPQDA-SSRESTPSMSQIDAQNNQD---
------AEPNFLSNQTD-------------THVVKVCMEEK--QD---------------
---------------------------------------------------TKRNYNNKD
QNTNLPEKEQKKKKMDSDTHRLLNTPKTKKGH-NFR-KQQSFLKSTCIQDL---------
------------------------------------YNYLTRIDRRSVKGKSQ

PF12796 // ENSGT00760000119090_5_Domain_3 (1434, 1528)

LHLAARR
GNLSYVKALIESGMDVNVKDNEGWT--PLHEASNKGCKDIIIELLKAGANVNCENINGIL
PLHDAVAGNHLKAAEILLQHGADPNKRDQKEKTAFDEADNEKMKELLKSYDVIETNDRNE
S------IKIPA--VPLKRCRQ---YFCDNDKT-FEPPSSSH--QAKRRESLPMHHTISD
ILQDIEEKQENLLEFEIRNSDDAGKHVLI-------FRYNLFQQQTTMDQWTKKIKKG-V
ISIESFKHGALREQLANLATRQKSLLLAAKRQKIIRQKIQSCKNVTSF---SLRTLPSSS
DISGKNDNK-KLTSLENSVHLQSD-----SLSAVNLACRSM-----------QETSLSLK
TWNDSQNAN-TCLNP-----EVVREEEFPVTEMNSKRIVN------------NSMLDDLT
KSRHLDGTDKIELPSQTV-----AEYSQK--EN-DLTEATAKDHGL--Y-TPTIKYGTLS
ISEYTSILSQNDVCPSAVDSNYDTSQCNPE-RRNRKTAPHQLSGGVSESL-----AQQRI
A-A-LG-TDATHQMKTYLK-KPSSAVPHLNNTQISPTSGSGNQH-TTKKPLNYTTAPKKR
NMQIKDLILLGRINPGNNILEFKTQETIHKASVLLSGKLQVENGQIYLTPVTWLKDLLGD
DIYVTWYYAWSKITYLGKELLRYVSEEGPLPSEQTMLLQQ-QPWH---------------
------------SGTSRESVQTIPHYLQ-IKEILSISDQEFLPCHVMAQHWKFYMECEEL
TF----