Query Results 

MADPEVCCFITKILCAHGGRMALDALLQEIVLPEPQLCEVLQVAGPDRFVVLETGGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDQIGHR-A
SLEDAPV---DDLTHKFTHLGSQDR-ARPPSGSSKPTD-LGGTSQAGASRRF-LENGSQE
DLLHGNPGSTYLASNS--TPAPNWKSLTSWTNDQGARRKTVFSPTLPAACSSLGSLQTPE
AVTTRKSTGLLSS-DYRNIDGKSGTQDIQ-PGPLFNNNADGVATD-ITSTRSLNYRSTSS
SQR-----------EISSPRTQDA-GPASRD----------------IQATG----RIAD
DADPRVALVNGKYKGKTLWASTFVHDIPNGSSQVADKTTDVEKTG--ATGFALTMAV--K
AEKDMLHTGSQSLRNLVPTSPGESTAPA----QVSTLPQSPA-ALSSSNTAAVWGAQGQN
CTQVPVSSASEL-TR----KTTGSAQCKSLKDK-GASVRVAMAGGFSLDVPQFLKGREL-
---------EGSCSKVHFH-PYRWQMLV-KTWMDFEHMEMIEENYCNPGIYLC-SVGNYT
INFRVMS-CDSFPIRRLSTPSSVT-KPANSVFTTKWIWYWKNESGTWIQYGEEKDKQK-S
SN--IDSSYLESLYQSCRRGV-VPFQAGSRNYELSFQ--GMIQTNIVSKTQKDVIRRP-T
FVPQ--WYVQQMKRG-PDH----------QPAKTSSVSLT--ATFRPQEDLC--LLSSKK

PF00644 // ENSGT00760000119084_5_Domain_2 (961, 1161)

YKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKRIENSELLDKFTRKKSQM-K-EEGKLL
FYATSRAWVESICVNNFDSFLHETH-ENKYGKGIYFAKDAIYSHKNCPYDA------KNV
VMFIAQVLV-GKFIEGSMTYT-SPP------PQFDSCVDTRLNP------------SVFV
IFQKDQIYPQ-----YVIEYTEAD-----------KACVIS---

MADPGVCSFITKILCAHGGRMALEALLREMQLSEAQLCEVLEEAGPDRFVVLEMGGKEGV
TRSVVATTR-ARVCRRKYCNK-PCGN-LHLCKLNLLGRCHYSQS-ERNLCKYSHEVLSED
NFRVLTNHGLSGLNQEELAVLLLQSDPFFMPEIC--KNYKGEGGRQVCNQQPPCERLHV-
CEHFTRGNCGYANCFRSHNLMDRRVLAVMRE-HGLSSSVVQNIQDICNSRHR--RKKPSA
WKAPPPHRRD-----PAYRGRSRSRDR---GSEEFLPAASTPAQRSCSAS-PEPAGHRGS
VPSDGPV---EDLAHKFSHLGSQEC-PPPASVPSAAVV-LGGTHQGGGSQKL-AENGSAK
DLFYGNHS------DL--TPAFNWKGPASWQNDQDTGKKSWLSSSPAFSFSPPGSPQTPE
TITTRKSTTVLSS-DHVNAECRSGNQDSQ-HFPLFDNKADGMAVD-TTSTRLANYQTPSS
SQR-----------EKSLPRNPDT-GTPRSH----------------LPTAG----KMT-
-GDGAAAFVN--------------------------------------------------
------------------------------------------------------------
--------------------------DSVPEAASTISSRMKEHSSNEICLDHLYKSCQL-
----------KSCNKVHFHLPYRWQMLLGNSWVDLPFMEDIEKAFCDPKNCSV-SVGNYN
ISFQKMI-CDFNPVRRISTPSSVT-KPASSLFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWRNGADEWVPYGEKKDNEH-I
SS--IDSSYLESLFLSCRRGV-VPFQAGSRNYELSFQ--GMIQTNIASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 971)

RRP-T
FVSY--WDVERVKRR-QDP----------QQGETSSEPFV--NIYLPQPDAS--VS----
--LLEIPNNT

PF00644 // ENSGT00760000119084_5_Domain_2 (971, 1117)

PEYAKVSDHFKASMRNFKIEKIKKVQNSQLLKAFKSKKMEM-K-REEQIL
FCAARRNNVASICENNFDWFLHGSH-DTKYGKGNYFTRDAISSHKNYPFDS------KNI
VMFVARVLV-GNFIEGHMGYQ-SPP------PRYDSCVDTRLNP------------SVFV
IFQKDQIYPE-----YVIEYTELE-----KSEKPEKPCVIS---

MADPEVCSFIVKVLCAHGGRMTLDALLEEIALSQGQLRQVLEDAGPDRFVLLQTRSSTGS
TWSVVANTR-ARVCRRKYCER-GCDN-LHLCKLNLLGRCHYTQA-DRKLCKYSHYVLSED
NFIVLKKYELSGLNQEELAVLLVQSDPFFIPEIC--KEYKGEGRKPTCSEHAACERLHI-
CEHFTRGNCKYLNCNRSHNLMDRKALAIMRE-HGLSPEVVQNIQDICNNKHA--RRNPPR
SRAPLNHRAP-----PASRGRSKSRDRFFQSSQEFISTAYKP-CT---PS-LGAMGFS-P
SLE----DGINNLEEEFSCLGREDL-AQSSSASAKVAS-LGGAPQAGGSQRA-SKDNGPD
SFFYRNHSDSTSSQA--------------------------------VSSSLLGFTKTPE
AITSNKS--LGNV-SSDHVKGKSGTQDIQ-QVLLKNK-ANGVAADLTSLRSVSYRAAAIN
DQR-----------EVTLSGNHLNNGSTFWD----------------LQTTGKKT--GDD
-NDPELTFLNGKYGATYKHTEEPTHS--------HYEVTNADQFC--VTGLGLKTAV--T
GEKDAFYLRSKGPRSQVPATPGEATASAG---V-SMLPQSPP-PS--SVRIGDYGAQGSS
FPQSSKGASYS--------------LYSM-SRISSITSTMNNAGPKEICLDHLYMGC---
-----------NCNKIHFHLPYQWQILISNTWRDLPAMEQIEEAYCDPQKH------NRE
IDFKKMI-CDFHPIRRLSTPSAAVPELANAVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWLWYWKHKSGKWIQYGYDN--QP-S
SD--IDSSYLESFYLSCPRGV-VPFQEGSRNFELSFQ--GMIQTNIASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 964)

RRP-V
FVSS--RDVEQIKAR-AVH----------QPLGSRSEALT--SEFHLQTVADS--LPAST
YEL

PF00644 // ENSGT00760000119084_5_Domain_2 (964, 1160)

LELNSYCQEYATISEQFKTSMKNFKIEKIKKINNPKLLDTFESKKWTM-NKRDEKLL
FYATSRAHVDSICANNFDYVLHGAH-ETKYGKGNYFTKEAIYSHKSYAC------DTKNT
VMFVARVLA-GEFIEGNMAYT-SPP------SMYDSCVDTRLNP------------SVYV
IFQKSQIYPA-----YVIEYVES-----------DKACVIS---

MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFKVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDQISHR-A
SLEDAPV---DDLTRKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGTSQRF-LENGSQE
DLLHGNPGSTYLASNS--TSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPE
AVTTRKGTGLLSS-DYRIINGKSGTQDIQ-PGPLFNNNADGVATD-ITSTRSLNYKSTSS
GHR-----------EISSPRIQDA-GPASRD----------------VQATG----RIAD
DADPRVALVNDS------------------------------------------------
------------------------------------------------------------
----------------------------LSDVTSTTSSRVDDHDSEEICLDHLCKGCPL-
---------NGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEKGYCNPGIHLC-SVGSYT
INFRVMS-CDSFPIRRLSTPSSVT-KPANSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDKRK-N
SN--VDSSYLESLYQSCPRGV-VPFQAGSRNYELSFQ--GMIQTNIASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-T
FVPQ--WYVQQMKRG-PDH----------QPAKTSSVSLT--ATFRPQEDFC--FLSSKK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM-K-EEGKLL
FYATSRAYVESICSNNFDSFLHETH-ENKYGKGIYFAKDAIYSHKNCPYDA------KNV
VMFVAQVLV-GKFTEGNITYT-SPP------PQFDSCVDTRSNP------------SVFV
IFQKDQVYPQ-----YVIEYTE-D-----------KACVIS---

MADPEVCCFITKILCTHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERGLEKSGLERLSI-
-----------------------------ITERLFFFCYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSGHR-A
SLDDTPV---DDLTHKFTNLGSQDR-ARPPLGSSKATD-LGGTSQAGASRSF-LENGSQE
DPLHGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTVFPPTLPATLSSLGSLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDVQ-PGPLFNNNADGVATD-ITSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPASRD----------------VQATG----RITD
DAGPRVALVNGKYKGKKLGASTFVHDTPNGSSQVADKTTDVEKTG--ATGFGLTMAV--T
GEKDKLRSGSQSLRSLVPITPGESTAPA----QVSALPQSPA-ALSSSNRAAVWRAQGQN
CTQVPVSPASEL-TR----KTTGSAQYSLSDVTRTTSSRVDDHGSKEICLDHLYKESPLN
SPSDPIFVFVGSCSKVHFHLPYRWQMLIGNTWTDFNPMEMIEEAYSDPRIHVC-SVGRYT
INFREMSCCDFIPVRRLSTPSSVT-NPANSVFTTT

PF02825 // ENSGT00760000119084_5_Domain_1 (816, 896)

WIWYWKNESGTWIQYGEEKDNQK-S
SN--IDSLYLESLYQSCPRGV-VQFQAGSQNYELSFQ--GMIQTNKVSKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSP--WDVQQRKRG-PDR----------QPAQTSSVSLT--ATFLPQEDLC--FLSSKK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1160)

EYVKVSEHFKASMKNFKIEKIKKIENPELLDKFTRKKSQM-K-EEESLL
FYATNRAYVESICANNFDWALHETH-EAKYGKGYYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYT-SPP------QRYNSCVDTRLNP------------SVFV
IFQKDQIYPQ-----YVIEYTDAD-----------KACVIS---

MADPGVCCFITKILCAHGGRMTLEELLGEIALPEAQLYELLESAGPDRFVLLEIGGQAGI
IRSVVATTR-ARVCRRKFCQR-PCDS-LHLCKLNLLGRCHYSHS-QRNLCKYSHEVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFLPEIC--KSYKGEGRKQICGQPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMKE-HGMSSDVVQNIQDICNNKHS--RRNPPA
MRAPHPHRRG-----GP-RGRSKSRDRFFQNSLELLPT-ASP-PESGPPS-PDVTSCK-D
SLEDVSA----DVTQKFKYLGTHDY-APLSSVTSKAAG-LRGTSQMGASLKF-SENGDPD
GLLSRNRSDSSPSQ--------------------------------AASGFHLDVTQTRE
AMTMTPG--KLSG-HRVDVEGKSETQDIQ-RIPFFDGYAGGANLE-GTASGILSNRATAN
GLG-----------EMALPSNHWKSAANPQD----------------PQTIG----RIAD
-GGQDSAFLSGNYGGDTVWASKSTHNAPSSSSQ-MNETSHVSGSS--PAGFGVKAAV--T
ERKEAVYSGVQSLGSQALAMPEKITAPEP---A-SSLPRSPP-PS-SSPRVAAFGTLGKN
PAHASVSPASEL-SR----MTSNSPEYPLCSFTSPASPRMDDRDPKEICQDYLYKGCQQ-
----------SSCGKHHFHLPYRWQMYLANVWRDFQDMENIEKAYCDPQSEVI-LVGKHQ
INFQKMT-CDSYLIRRLSTPSSVA-PSAKSVFST

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

TWLWYWKNEFNQYVQYGEERKGQP-S
SN--ISSQYLESFFQSCPRGV-MPFQAGSQNYELSFQ--GMIQTNIASKTQRHVV

ENSGT00760000119084_5_Linker_1_2 (896, 962)

RRP-V
FVSL--KDVEQRRRG-SDL----------QPVMPQPKIS---------------IIPSSG
Y

PF00644 // ENSGT00760000119084_5_Domain_2 (962, 1160)

ELLELNSQDVEYVKISELFKASMKNFNIAKIKRIWNQNLLETFERKTLMM-KNKNEMLL
FHATCRAHVDYICKNNFEWILHGNR-ETRYGKGNYFAKEAFYSHKNCPYDA------RNI
VMFVARVLV-GDSIEGNMTYS-RPP------ALYDSCVDTRLNP------------SVFV
IFQKEQIYPA-----YVIEYTDPE---------KEKSCVIS---

MADPEVCCFITKILCAHGGRMALDALLEEIALSEPQLCEVLQVAGPDRFVVLETSGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRILKNHELSGLNKEELAVLLLQSDPFFMPEVILCHRYFG-GRQQIGTQPARVQDSTI-
CDHSP-EQLSFPNCPPSQYLMDRKVWAE--------PPTGANIQDSLQQQHM--QKNPRR
P-----EERN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSSHR-A
SLEDTPV---DDLTHKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGASRRF-LENGSQE
DLLHGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTVFPPTLPAALSSLGSLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDVQ-PGPLFNNNADGVATD-TTSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPASRD----------------VQATG----RITD
DAGPRVALVNGKYKGKKLGASAFVHDTPNGSSQVADKTTDVEKTG--ATGFGFTMAV--M
VEKDKLRSGSQSLRSLVPTTPGESTASA----QVSTLPQSPA-ALSSSNRAAVWRAQGQN
CTQVPVSPASEL-TR----KTTGSAQYSLSDVTSTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGSCSKVHFHLPYRWQMFIGETWTDFKPMEMIEEAYSDPRIHVC-SVGSYT
INFREMS-CDFIPIRRLSTPSSVT-KPTNSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDNQK-S
SN--IDSLYLESLYQSCPRGV-VQFQAGSRNYELSFQ--GMIQTNKASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSQ--WDVQQMKRG-PDR----------QPAQTSSVSLT--ATFLPQEDLC--FLSSNK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1160)

EYVKVSEHFKASMKNFKIEKIKKIENLELLDKFTRKKSQM-K-EEGSLL
FYATSRAYVESICANNFDWARHETH-EIKYGKGYYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYM-SPP------QPYNSCVDTRLNP------------SVFV
IFEKDQIYPQ-----YVIEYTDAD-----------KACVIS---

MTDPEVFCFITKILCAHGGRMTLEELLGEISLPEAQLYELLKTAGPDRFVLLETGDQAGI
TRSVVATTR-ARVCRRKYCQR-PCDS-LHLCKLNLLGRCHYAQS-QRNLCKYSHNVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICGQPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMRE-HGLSSDVVQNIQDICNNKHT--RRNPPG
MRAPHPHRRG-----GVHRDRSKSRDRFHYNSLEVLST-VSP-LGSGPPS-PDVTSCK-D
SLEDMSA----DVTQKFKYLGTHDR-AQLSSLSPKAAG-VRGPSQMRASQEF-SENGDPD
GLFSRNRSDSSTSRT-------------------------------SAAGFPLDAAQRNE
AGAVKIG--IPSG-HHIEVKGKN--KDVD-HVPFLNSYIGGVTMEEATVSGILGKRATDN
DLE-----------EMMLPSNHRKSVAKTQD----------------PQTAG----RITD
-SGQDTEFLQSKYGENPAWAGTSTHNGPNGFSQIMDETPNVSKSG--TTGFGVKSAV--T
GGKEAVYSGVQSLRSHVLAMPGETTTPVQ---GSNRLPPTPL-SS-SSHRVAASGSPGKN
SSHASVSPASEP-LRMMTMMMSDPAEYPLSYIVNPVSPGMDDHDPKEICLDHLGRGCRQ-
----------SNCNKSHFHLPYRWQLFILPTWMDFQDMEYIERAYCDPRIEII-LIEKHR
IDFQKMS-CNSYPIRRLSTPSFVE-NTLNSAFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWLWYWKNELNEYTQYGDESPGHT-S
SD--INSAYLESLFHSCPRGV-LQFHAGSQKYELSFQ--GMIQTNIVSKTQRRVV

ENSGT00760000119084_5_Linker_1_2 (896, 962)

RRP-V
FVSS--KDVKQQRTG-PDH----------QPVTPQADALS--LYSPPQRNASA--VSPNE
Y

PF00644 // ENSGT00760000119084_5_Domain_2 (962, 1054)

EFIELDSQDEEYAKISEQFKASMKHFKIVTIKRIWNQKLWDTFESKKQKM-KNKTEMFL
FHAACRIHVDYICKNNFEWILHGNR-ETRYGKGLCWRRESCDCSRVRGFIEMMPCDCSSA
HGFIEMMPCDRSRVRGFVE--------------MMPCDRSRMRGFIEMMPCDRSRVRGFV
EMPLASLYRP-----ASLGSSGLQ---------RK---------

MADPEVCCFITKILCAHGGRMALDALLEEIALSEPQLCEVLQVAGPDRFVVLETSGEAGI
TRSVVATTR-ARVCRRKYCQR-LCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KNYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSSHR-A
SLEDTPV---DDLTHKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGASRRF-LENGSQE
DLLPGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTVFPPTLPAALSSLGSLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDVQ-PGPLFNNNADGVATD-TTSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPASRD----------------VQATG----RITD
DAGPRVALVNGKYKGKKLGASAFVHDTPNGSSQVADKTTDVEKTG--ATGFGFTMAV--M
VEKDKLRSGSQSLRSLVPTTPGESTASA----QVSTLPQSPA-ALSSSNRAAVWRAQGQN
CTQVPVSPASEL-TR----KTTGSAQYSLSDVTSTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGSCSKVHFHLPYRWQMFIGETWTDFKPMEMIEEAYSDPRIHVC-SVGSYT
INFREMS-CDFIPIRRLSTPSSVT-KPANSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDNQK-S
SN--IDSLYLESLYQSCPRGV-VQFQAGSRNYELSFQ--GMIQTNKASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSQ--WDVQQMKRG-PDR----------QPAQTSSVSLT--ATFLPQEDLC--FLSSNK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1160)

EYVKVSEHFKASMKNFKIEKIKKIENLELLDKFTRKKSQM-K-EEGSLL
FYATSRAYVESICANNFDWALHETH-ETKYGKGSYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYM-SPP------QPYNSCVDTRLNP------------SVFV
IFEKDQIYPQ-----YVIEYTDAD-----------KACVIS---

MADPSVCCYLTKLLCAQGGRMALDALLGEIALSEEQLCEVLKAAGPDRFVLLDTGA----
VRAVVATTR-ARVCRRKFCQR-PCEN-LHLCKLNLLGRCNYSHA-DRXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIC--KSYKGEGRRQICSQQPPCTALHI-
CEHFTRGNCSYTNCLRSHNLLDQKVLAIMEE-HGLHQDVVQNIQDICNSKHT--QKNPPG
RRAPPPHRRD-----VPYRGRSKSRDRTLKDSQEFLPPARDSSLNSCAADH-EKVSRR-S
SLDDEAM---EALTHKLLHLGSRHS-SPPPLVSTKATG---PASQKGANFTL-SENDSRE
GLFYGRSGSTHLVPGS--TPASIWKECTSGVDSLGIWGGGAFPPNPP--VPT--------
-----RSLSMLSS-DIKAGNG---------PGPL-SNRVDRVTTD-LSPTGPPSYKAT--
---AS-RE-Q-EE---SLSKDQDP-RPIPRA----------------PLGTG----KIPE
DGA---------------------------------------------------------
------------------------------------------------------------
---------------------AVVSKNPNSSVTSISSSKR-DGGSKEICLDYLQECCQE-
---------GXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXF-SVMDYH
IDFQTMT-CNSKLLRRLSTPSSGT-KLTSLVFATQWVWYWRSRSDIWVKYGEKSSNQG-I
SN--ISSSYIEDMFLAYPKGI-VPFKAGFEAYELSFQ--AMIQTNVLSRTQKHVLRRP-K
FLSS--SDLELLKIR-RXXXXXXXXX----------XXXX---XXXXXXXXXX-XXXX

PF00644 // ENSGT00760000119084_5_Domain_2 (959, 1162)

XX
XXLSPISDQHPEYIVISASFKASMKNFKIEKIQRIHNPALLTAFQRLKVFM-RNANEKTL
FHATDRRYVESICQHNFDWSLHGTC-EAKYGKGNYFTKEAISSHKNCLVDN------QNR
VMLVSQVLV-GDYTEGKVVYT-RPP------PKYDSCVDTRLNP------------SIFV
IFQKDQIYPQ-----YVIDYSETD-----------KVCVIS---

MADPTVCCFVTKILCAHGGRLSLDALLEKIELSEAQLLEVLKEAGPDRFVVLETGGRAGV
TRSVVATTR-ARVCRRKFCERSSCDN-LHLCKLNLLGRGHYSQS-ERNLCKYSHDVLSEK
NFQVLKNHELSGLNQEQLAVLLLQSDPFFMPEIC--KSYKGEGRKQICNQQPPCERLHI-
CEHFTRGNCSYPNCLRSHNLMDRKVLAIMRD-HGLSPAVVQNIQDICNNKHM--RRNPPG
SKTP-VHRRA-----RAARGRSKSRDRVSQDIKEFLPSAS--AHKSGTPS-PDGTDSR-A
SLEDDPM---DDLIHKFEFLETPDC-TQPSSVSSKAAG-LGRPGQVGTSQRF-LENGIPD
GLFHSNQSH--LASNS--TPASNQKGSPSWLNAQGTGKESEFFPSQAVPSFPLDSTQTLK
ALNSRKVVGMLSS-DHMNVKDKSGSQDIQ-RIPIFSRNADGVAMN-------MNFGKT--
AQR-----------EMALSSYQD-SRATPRD-----------------LHIG----SIAS
-DDARVAFLND-------------------------------------------------
------------------------------------------------------------
---------------------------SISDITNTT-SRMGNLGPEGICVDYLHNRCQP-
---------NSDCSKIHFPLPYRWQVLMSHTWKDLEDMEKIEKAYCNPRSHVL-SIENHI
LDFQKMT-YALKPIRRISSPSSGM-NQASTVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWENESGEWIQYGKGSNNQP-G
SN--IDSSYLESFFQKCPRGV-VPFQAGTRNYELSFQ--GMIQTNIASKTQKNVV

ENSGT00760000119084_5_Linker_1_2 (896, 961)

RRP-E
FVSA--RDVEQMRRG-PDPQRVQFSASSPQPVHTPPEAVG--STFVPQWDVL--SPTSSG

PF00644 // ENSGT00760000119084_5_Domain_2 (961, 1117)

YKLLDLDNQSLEYATIRDNFKESMKNFKIEKIKKIHNPELLNSFERRRLNM-TEKRERLL
FYATSRTHVDSICANNFMWNLHGTH-ENKYGKGNHFSKDAIYSHKNCLYDA------RNI
VMFVARVLA-GDFIEGNMTFV-SPP------PPYNSCVDTMLNP------------SVFV
IFRNDQAGFCQKQTVYLEDESKTLVGNKEDSHGKE---------

MADPEVCCFITKILCAHGGRMALDALLQKIALSERQLCEVLQVAGPDRFVVLETGGEAGI
TRSVVATTR-ARVCRRKYCQR-SCDN-LHLCKLNLLGRCNYSKS-ERNSCKYSHEVLSEE
NFEVLKQHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFLQGSQEFLGSASASAERSCTPS-PDQIGHR-A
SLEDAPV---DDLTRKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGASQRF-LENGSQE
DLLHGNPGSTYLASNS--TSAPNWKSLTSWTNDQGARRKTVFSPTLPAARYSLGSLQTPE
AVTTRRGTGLPSS-DYRIINGKSGSQDIQ-PGPLFNNNADGVATD-ITSTRSLNYKSTSS
GQR-----------EISSPRIQDA-GPASRD----------------VQATG----RIAD
DADPRVALVNGKYKEKTLWASTFVHDIPNGSSQVVDKTTDVEKTG--ATGFGLTMAV--K
AEKDMLRTGSQSLRNLVPTTPGESTAPA----QVSTLPQSPA-ALSSSDRAAVWGAQGQN
CTQVPVSSASEL-TR----KTTGSAQYSLSDVTSTTSSRVDDHDSKEICLDHLCKGCPL-
---------NGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEEGYCNPGIHFC-SVGSYT
INFRVMS-CDSFPIRRLSTPSSVT-KPANSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDKRE-N
SN--VDSSYLESLYQSCPRGV-VPFQAGSRNYELSFQ--GMIQTNIASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-T
FVPQ--WYVQQMKRG-PDH----------QPAKTSSVSLT--ATFRPQEDFC--FLSSKK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM-K-EEGKLL
FYATSRAYVESICANNFDSFLHETH-ENKYGKGIYFAKDAIYSHKNCPYDA------KNV
VMFVAQVLV-GKFIEGNITYT-SPP------PQFDSCVDTRSNP------------SVFV
IFQKDQVYPQ-----YVIEYTE-D-----------KACVIS---

MADPEVCCFITKILCAHGGRMALDALLQKIALSELQLCEVLQVAGPDRFVVLETRGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLSPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----TAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDHIGHR-A
SLEDAPV---DDLTYKFTYLESQDR-ARPPSGSSKATD-LGAKSQAGASQRF-LENGSQE
DLLHGNPGNTYLASNS--TPAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPE
AVTNRKGTGLLSS-DYRNIDGKSGTQDIQ-PGPLFNNNADGVATD-ITSTRSLNYKSTSS
GQR-----------EISSPRTQDA-GAASRD----------------VQATG----RIAD
DADPRVALVNGKYKGKTLWAGTFVHDIPNGSSQVADKTTDVEKTG--ATGFGLTMAV--K
AEKDVLRTGSQSLRNPVPTTPGESTAPA----QVSTLPQSPA-ALSSSNRAEVWGAQWWN
CTQVPVSSASEL-TR----KTTGSAQ----------------------------------
----------CSCSKVHFHLPYRWQMLIGKTWTDFEHMEMIEKDYCNPGIHLC-SVGVYT
INFREMS-SDFFPIRRLSTPSSVT-KPANSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDKRK-S
SN--IDSSYLESLYQSCPRGV-VTFQAGSRNYELSFQ--GMIQTNIASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-T
FVSQ--WYVQQMKRG-PDH----------QPAKTSSVSLT--ATFRPQEDLC--FLSSKK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYVKVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM-K-EEGKLL
FYATSRAWVESICANNFDYFLHETH-ENRYGKGIYFAKDAIYSHKNCPYDA------KNI
IMFVAQVLV-GKFIEGNMTCT-SPP------PQCDSCVDTRLNP------------SVFV
IFQKDQIYPQ-----YVIEYTEAD-----------KPCVIS---

MADPEVCCFITKILCAHGGRMALDALLEEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHHRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSGHR-A
SLEDTPV---DDLTHKFTNLGSQDR-ARPPLGSSKATD-LGGTSQAGASRRF-LENGSQE
DPLRGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTVFPPTLPATLSSLGSLQTPE
AVTTRKGAGLLSS-DYRNVNGKSGTQDVQ-PGPLFNNNADGVVTD-ITSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPASRD----------------VQATG----RITD
DAGPRVALVNDS------------------------------------------------
------------------------------------------------------------
----------------------------LSDVTRTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGSCSKVHFHLPYRWQMLIGKTWTDFNHMEMIEEAYSDPRIHIC-SVGSYT
INFREMSCCDFIPVRRLSTPSSVT-NPANSVFTTT

PF02825 // ENSGT00760000119084_5_Domain_1 (816, 896)

WIWYWKNESGTWIQYGEEKDNQK-S
ST--IDSLYLESLYQSCPRGV-VQFQAGSRNYELSFQ--GMIQTNKVSKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSP--WDVQQMKRG-PDR----------QPAQTSSVSLT--ATFLPQEDLC--FLSSKK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1160)

EYVKVSEHFKASMKNFKIEKIKKIENPELLDKFTRKKSQM-K-EEGSLL
FYATSRAYVESICANNFDWTLHETH-ETKYGKGSYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYT-SPP------QRYNSCVDTGLNP------------SVFV
IFQKDQIYPQ-----YVIEYTDAD-----------KACVIS---

MADPEVCCFITKILCAHGGRMALDELLEKIVLPEAQLCDLLEQAGPDRFVVLETGSKAGV
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-D--------------
-------------------------------------RYKGEGRRQICSQQPGCDRLHI-
CEHFTRGNCSYLNCLKSHNLMDRRVLAIMRE-HGLSADVVQSIQDICNSKHM--RKNPSG
SRAPSSHRRA-----GPYRARSKSRERFFQGSQEFLPSAAASAQRSSTPS-PDPMGRR-A
PGDDVPV---DGLTHKFTYLGTRDC-AQPSSASAKATD-LGGAGEGGASQRF-SENGSPK
GLFYGNQGNTYLVSDS--TPASNWKDPTPWPKDQGTGNESVFSPILTATR-SLGSAQTPE
AVTTRKNTGMLYS-DLRDVQGRSGTQDIQ-HVSLFNNNADGGATG-VTVARYFNYNE---
CQR-----------ETPLLRNPDS-GPTSRD----------------LQTTG----KITE
GDNAGVAFINGKYGGKTFLASKTVHSAPNGSSEITDKTTNVVMEKTGATGFGLKTAV--I
GEKDVLCSGSQSLRSQIPATPGETTAPA----LVSTLLQSP----SSSNRAAACGTLGQN
STQVPFPPASES-AR----RTPGSAQHSISDVAGTTSSRVHDPSLEKICPDHLHKGCQL-
---------NGDCDKDHYDLPYRWQKLR-EKWEDFESMEKIEEAYCDPQNHVV-SVAEGT
IDFEKMI-CGSMNVRRMSTPASVV-KPANSVFTTEWIWYWKNENGKWIPYGEEVSII---
--------------PPCG----------------RLL--WMIQTNIASKTQKDVIRRP-K
FVSP--WDVKHKGRR-LDY----------QLMQTPSEPLT--STFLPQQDLG--SLPSNG
FKVLAFY-----------------------------------------------------
-LFGG

PF00644 // ENSGT00760000119084_5_Domain_2 (1026, 1161)

YTHVESICAKNFNWNIHETH-EPKYGTGNYFAKDAIYSHKNCPYDA------RNI
IMFVARVLV-GNFTEGDKTYT-SPP------PQYDSCVDTCLNP------------SVFV
IFEKDQIYPQ-----YVIEYTEAD-----------KACVIS---

-----------------------------------------------------------V
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NYRVLKIHELSGLNQEELAVLLLQSDPFFMPEIC--KSYKGEGRKLICSQQPPCERLHI-
CEHFTRGNCSYPNCLRSHNLMDRKVLAIMRE-HGLKPNVVQNIQDICNSKHA--RRNPPG
SRALSSHRRN-----VAYRARSKSRDRYFQGSQEFLLSASASAQRSCTSS-PDLIDCK-V
SLEDEPI---DDLAHKFTYLESQDR-AQPSSVSSKATD-FGGIGQAGVSRRF-PENGGPE
SIFFGNQGDTYLASDS--TPASNWKSPTSWTNDQGTRMENVFSPVLTLAHSP-PPAQIPE
AMTTRRSTDVLSS-DRRNIQGNSGIQDLQ-HGSLFNNNADGMATD-FTSLRSLRYKSTTS
AQG-----------EMSLPRNQDT-GATSRD----------------FQTTG----RVTG
DDDPGVALVNGKYSGKIFWASKSVHSAPKSSSQVIDKTTDAEKTG-----------V--T
GGKDVFHLGSQSLRSQVPAIPRETSAPT----HVITLPQLPS-PLCASNTVAAYRACGQN
STQDPASHASEF-TR----RTPDSL----SGVV-NTTSTVDDLGSEEICLDHLDKHCQF-
---------NSSCNKVHFHLPYRWQILLVRTWMDCQSMEKIEEAYCDPQINVF-SGGNHT
INFQKMT-CDSHPIRRLSTPSSVR-KSADSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWRNESGKWIQYGEKKDNQK-S
LN--IDSFYLESLYQSCPRGV-VPFQAGSQNYELSFP--GMIQTNIVSKTQKDVIRRP-T
FVSL--RDVEQMRRG-P-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

MADPGVCCFITKILCTHGGRMALEELLQKVKLSEAQLCEVLTTAGPDRFVLLETGGKAGV
TRSVVATTR-VRVCRRKYCNR-QCGN-LHLCKLNLLGRCHYSQS-ERNLCKYSHEVLSDE
NFRVLNSHELSGLNKEELAVLLVQSDPFFMPEIC--KNYKGEGGRQICNQQPPCERLHV-
CEHFTRGNCSYSNCFRSHNLMDRKVLAVMRE-HGLSSSVVQNIQDICNSRHR--RNKPSG
ARAPSSHRRD--------RGRSKSRERLCQDSVEFLPSASAAARVSRTPS-PDSAGRH-S
SPDDGLV---EHLATKFKGLGSHDC-PQLSSVSSAATS-QGGTGPRGGSQSF-LENGSPE
SLLLVNCGGSIFSLAS--PPAPNWKGPTSWQNNKDPSRESSFSPNQAVTFSPLGSPQTPQ
ATSTRKSPTLFSS-DFVNLEGRSGNQDGQ-PFQLFHNNVDAVATD-VASRKSLSYKSATS
RQR-----------EKSLPRSPDA-GAAHGL----------------LQPAG----KVAE
DAAAAA-FGN--------------------------------------------------
------------------------------------------------------------
--------------------------GSAPDARSTASSMMDDHGSNEICLDHLDKGCQL-
----------KNCSKVHFHLPYRWQMLSANTWMDLSLMENVEEAFCDPKVSVL-SIGNYK
LNFQEMT-CDYNPIRRLSTPSSVT-RPPGTVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 895)

KWVWYWKSGPNTWVRYGEKKDNQ--I
SN--IDSAYLESFFLSCPRGI-VPFQAGSQNFELSFP--GMIQTNVASKVQKDV

ENSGT00760000119084_5_Linker_1_2 (895, 962)

VRRP-T
FVSH--WDVEQMKRG-MGP----------PQVQPQLEPPA--PTFLPQWDTH--FSASNG
Y

PF00644 // ENSGT00760000119084_5_Domain_2 (962, 1161)

KLLEIHNYTPEYVEVSGRFKASMKNFKIDKIKKIQNTKLLNAFERKKHEV---KVERIL
FCVKRRADVESICANNFDS--DGTH-DTKYGKGIYFTKDAISSHKDCPYDS------KNV
AMFVVRVLV-GNFVEGHPYF-TSPP------LGFNSCVDTRLNP------------SVFV
IFEKDQIYPE-----YLIEYTETD-----------KPCVIS---

MADPEVCCFITKILCAHGGRMDLDKLLEKIVLPEAQLRDLLEQAGPDRFVVLETSSSAGV
TRTVVANTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-DRNLCKYSHEVLSAE
NFKILKMHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRRQICNQQPGCDRLHI-
CDHFTRGNCGYLNCLKSHNLMDRKVLGIMRN-HGLNADVVQSIQDICNSKHM--RKNSPG
LRAP-FHRRA-----GPYKARSKSRERFFHGSQEFLPSS---TQRSSTPS-PDPTGRS-A
PGDDVPV---DGLTHKFTYLETQDL-AQPSSPSAKATN-LGGAGEDGASQRF-SENGSPK
GLFYGKQSNTYLVSDS--TPASNWKDPTPWPKDQGTGKESVFSPILTAARPPLGSAPTPE
AVTAGNSTGMLYS-DLRDTKGRSGTQDLQ-HVSLFHNNADGGAAG-VTSARYFNYNSTTN
SQR-----------ETSLPRDRDA-GPASRD----------------LQTTG----QITE
GDTAAVAFVNGKCGGKTFSASKTTHSSPDGSSDIMDKTTNVLIEKTGATGFGLKTSV--T
GGKDVLCSGSQSVRSQALATPGETTAPA----PVSTLLQSP----SSGNRAAACGTLGQN
STQVPVPPAGES-TR----RTPGCAQYSISDVVGTMSSWVHDPSLEKICLDHLHEGCQL-
---------NESCDKDHFHLPYRWQKLSGKKWEDFEHMEAIEEAYCAPQNCVF-LAGKGR
IDFENMI-CDSMPIRRMCTPTSIG-KAADSVFTTE

PF02825 // ENSGT00760000119084_5_Domain_1 (816, 896)

WIWYWRNEYGKWIPYGEEKDNQK-G
SN--IDSSYLESVYQHCPRGV-VRFQAGPRNYELSFQ--GMIQTNIVSKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSS--WDVNQKRRW-PDY----------QPVQTTPEPLS--STFLPQQDPG--FLPSNE
FKLLELNNQHL

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYAKISKHFGASMKNFKIEKIKKIQNQNLLDNFNRKKKQM-KKEEEKLL
FYATRHTHVDSICAKNFNWTIHETH-EPKYGTGNYFAKDAIYSHKNCPYDA------RNI
IMFVARVLV-GNFIEGDKTYT-SPP------PQYDSCVDTSLNP------------SVFV
IFEKDQIYPE-----YVIEYTEAD-----------KACVIS---

MADPGVCCYITKILCAHGGRLALEKLLEESGLPEAQLGQELEAAGPDRFVILETGSKDGV
SRSVVATTK-VRVCRRRFCQR-PCNN-LHLCKLNLLGRCNYAQS-ERXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIC--KTYKGEGQKQVCNQNMGC

PF00642 // ENSGT00760000119084_5_Domain_0 (175, 200)

ERLHI-
CEYFTRGECSYLNCLRSHNLMDRKVLAVMKT-HGLSPETVLNIQDICNSQHP---ENASG
PRAPPSHRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX--
XXXXXXX---XXXXXXXXXXXXXXX-XXXXXXXXXXXX-XXXXXXXXXXXXX-XXXXXXX
XXXXXXXXXXXXXXXX--X----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXMFLP-DLENTNGKSGMADSS-HVRL-GNDANAGAPE-TASSRSANCKTVKD
AER-----------EMLSCRIQKAPGTSPWD----------------SPSTG----KVRH
AGDPGMGFLY--------------------------------------------------
------------------------------------------------------------
--------------------------ASESDVPSPASSNMNDHGSKQICLKYLYNGCRQ-
---------NSSCNQIHFNLPYRWQLFIANNWVDFKDMERIEEAYCDPKVQII-SLGNHT
INFQEMT-CDRTLMRRISTPSTIT-DSFFSIFATKWIWYWRSESSKWTPYGEQHNNQP-A
SS--VDSLYLESVFQSCPRGV-VPFQAGVRSYELSFQ--GMIQTNIVSKTQREVVRRP-T
FVSV--WEVEQMRRI-PGY----------QPRSTQAEPLLT--AAVLQPNLD--LLPPD

PF00644 // ENSGT00760000119084_5_Domain_2 (960, 1162)

G
YKLMELRPSCPEYLGISGHFKVSMKNFTIEKIQKIE-SELLQAFERKKSRM-TNDDEKLL
FYATSRVYMESICRNNFDWTLHGPH-ETKYGRGGYFAKDAMYSHKNCLVDT------RNT
VMFVARVLP-GLFIEGNRMST-SPP------PQYDSCVDTTLNP------------SVFV
IFQKDQVLPA-----YVIEYSETD-----------KACVIS---

MADPGVCCFITKILCAHGGRMTLDELLGEIALPEPELRDLLLTAGPDRFVLVESGGRAGV
ASSVVATTR-ARVCRRKYCQS-HCEN-LHLCKLNLLGRCHYSQA-ERNLCKYSHEVLSEE
NFQVLKHHQLSGLNKKELAVLLVQSDPFFMPEVS--EDSPGQAGRGWV------------
----AGGALSWM-CWCGSSAISQ------------STPGLRSPGTQCQEPQS--SHFGFV
FPGPSAHRRG-----AA-RGRSKSRDRFFHGSHEFLPAASAS-Q---RSS-PDRTGCE-E
LLDDKP---VGDLTYKFKYLGSQDH-AQPSSVSSKVAG-LGGPGPMGGSQKF-SENGGLD
GPFYRNHSESSPSRA--------------------------------ATAASLDSVPARE
AAPIRKG--MIST----DLKGT-------------SGFADGVAMD-GKSTRSSNYRATVN
GQR-----------ERTVPSSYQNSSASPWD----------------PQTTS----RNTD
-DDPGVTFLNGKYRGTPVWAGPSVHSVSNGSSQILDEIPKVDAAS--ATGFGLKAAV--T
RGKEALYSGGQNLRGQVPASPT---APAQ---T-SGLPQSPL-PS-PSHKAAAPGTPGQK
SAHTAVSPPSGL-SRGTPVSDQSK-----SLDRGSSSSRMDDHGSKEICPDYLLQGCQL-
----------RNCNKIHFHLPYRWQVLMSSTWTDFGDMEKIEQAYCDPQNQNF-LIGNHQ
IDFQKMT-CGVNPVRRMSTASTVS-EQANSVFNT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWLWYWKSKSGKWIQYGEE----P-S
SN--IDSSYLESFFQQSHSKGVVPFQAGSRNYELSFQ--GMIQTNILSKTQRDVI

ENSGT00760000119084_5_Linker_1_2 (896, 963)

RRP-L
FISS--QDVQQMKRW-TEY----------QPVNTQAEALT--SSFLPQRDDSS---SSSA
YR

PF00644 // ENSGT00760000119084_5_Domain_2 (963, 1161)

LLELNSQHVEYIKISECFKASMKNFKIEKIKRIWNPRLLEAFQRRKEKM-QKKDEVLL
FHAASRAHVYSICVDNFDWTIHENH-ETKYGKGNYFAKEAFYSHKNCPYDS------RNI
IMFVARVLV-GDFIEGHMLYR-RPP------VQYDSCVDTRLNP------------SVFV
IFEKDQIYPE-----YLIEYTEI-----------DKPCVIS---

MADPGVCCFITKILCAHGGRMTLEGLLAEIALPEAQLCELLEAAGPDRFVLLEIVGQTGV
TRSVVATTR-ARVCRRKYCER-PCDS-LHLCKLNLLGRCHYSHA-QRNLCKYSHEVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFMPEVG--PNSQA------C-QLRSCNRDT--
---MARGDLSL----------------------------------------N--FSFRFL
FSAPQPYRRG-----RA-RGRSKSRDRFFQNSLEFLPT-VSP-AESGPPS-PDASSCK-D
PLEDVFA----DVTQKFKYLGTQDC-AQLPAAPPKAASQMGGASQMGAGLKF-SENGDPG
GLFSRSPSDSFLNQ--------------------------------AASGLHLDVTQTLE
AMATKTN--KPSG-HRIDVKSKNEVHDVL-QAPFFDSYAGGATME-GTASGILGSRATAN
GLG-----------EMILPSGHQKSAANPQG----------------PQTTG----RITD
-SSQDAAFLSGRYGGNAVWASKSTHSEPNGSSQVMNGTPDVSKSS--AAGFGVKAAV--A
GRKEATCPGGQSLRGQVLAVPEEITAPVQ---A-SRLPQSSP-TS-SSHRVAAPGTLDKN
SARTSVNPAHKP-SR----GTS-DSEYPPCPITSSASLKTDDHGPKEICQDYLHKGCLQ-
----------SNCSKSHFHLPYRWQVFLDNCWVDFQAMEDFERAYCDPQNEVI-TIGKHQ
INFQKMT-CGSYPIRRLSTPSFDA-QSVNSVFST

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWLWYWRNEFNKYVQYGDERESQF-S
SD--ISSPYLESVFQSCPRGV-VQFQAGSQHYELSFQ--GMIQTNIASKTQRHVV

ENSGT00760000119084_5_Linker_1_2 (896, 961)

RRP-V
FVSR--TDVEHRRRG-ADW----------QPVMPVVEALT--LDSPPQRNTST--FPSNR

PF00644 // ENSGT00760000119084_5_Domain_2 (961, 1161)

YELVSLDSQDVEYVTISELFKASMKYFKITTIKRIWNEDLWNTFERKKVAM-RNSNEMLL
FHATCRAHVDYICRSNFDWILNGSR-ETKYGKGNYFAKEAMYSHKNCPYEA------KNI
VMFVARVLP-GNSIEGNVTYS-RAP------ALYDSCVDSRLNP------------SVFV
IFKKEQICPA-----YVIEYTELE---------KEKPCTIS---

MADPEVCCFITKILCAHSGRMAMDALLQEIKLSEAQLCEVLQVAGPDRFVVLETGGVAGV
TRSVVATTR-ARVCRRKYCRS-PCDN-LHLCKLNLLGRCNYSQS-DRNLCKYSHEVLSED
NFRVLKIHELSGLNQEELKVLLVQSDPFFMPEIC--KSYKGEGRQQICSQEPPCARLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLSPDVVQNIQDICNSKHM--QKNAMG
PRAPA-HRGN-----LAHRARSKSRDRFLQGSQEFLASASASAQRTCTPS-PDQIGHR-A
SLEDVPV---DDLTYKFAYLGSQAH-TRLPSGSSKATD-LGGTSQAGASRGF-SENGSLH
DILYGNPGDTYLASDS--TPASKWKGPTSWTNDKGTGRESMFSPTLPAACSSLGCLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDMQ-PGPLFNNNADGVATD-ITSTRSLNYKSTNS
GQR-----------EISSPRNQDA-GPASRD----------------LQATG----RITG
GTDPRVALVNGKYRGKTLWASTFVHDALTGSSKVADETIDVGKTG--ATGFGLTMA---V
MGEKDI--------SLVPATLGETAVPA----QVSTLPQSPA-TLSSSNRAAVWGSQGQN
YP----------------------GSYSLSDVTSTTSSRVDDHGSKEICLDHLYKGCPL-
---------NGSCTRVHFHLPYRWQMLISRTWTDFQFMEKIEEAYCDPQIHLC-SVGSYT
INFREMT-CGSNPIQRLSTPSSVT-KPGNPVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGRWIQYGEEKDNQK-S
SS--IDSSYLEAFYQSCPRGV-VPFQAGSRNYELSFQ--GMVQTNVASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSL--WDVEQMKRR-PDH----------QPAQTSSTPIT--ATFLPQQDLC--FLSSKK
YKVSEINHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYVKVSEYFKASMKNFKIEKIKKIQNPELLDCFTRKKLQM-K-VEENLL
FYATKRAYVDSICANNFDWTLHETH-ATTYGKGFYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFTEGNMTYT-SPP------PLFNSCVDTRLNP------------SVFV
IFHKDQIYPQ-----YVIEYTETD-----------KPCVIS---

MADPGVCCFITKILCAHGGRMTLEELLNEIALPEAQLYELLEAAGPDRFVLLEIGGQAGI
TRSVVATTR-ARVCRRKICQR-PCDS-LHLCKLNLLGRCHYSHS-PRNLCKYSHEVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICGQPQPCERLHI-
CEHFTRGNCGYLNCLRSHNLMDRKVLAIMKE-HGLSSDVVQNIQDICNNKHS--RRNPPV
MRAPHSQRRR-----GA-RGRSKSRDRFFHNSLELVPP-VSP-PESGPPS-PDVSSCK-D
SLEDVSA----DVTQKFKFLGTHDC-AQLSAASSKTPG-LRGAGQMGASLKF-SENGDPN
GFFSRNHADSSPSQ--------------------------------AAGGFRLDVTQTHE
AMAVKSS--KPSG-PHMDVKGKSEAQDKQ-KVPFLGSYAGGAAVE-----GILGDRGTVN
GLG-----------EVTLPSNHQKSTANPQD----------------PRTTG----RITN
-SGQDMAFLGGKYGGNTPWPIKSTHNVPNGSSQILNETPKNSESS--AIGFGVKAAV--T
GRKEAMCSGVQSLRNQIPAMPEEFTAPAQ---A-SRLPLSPA-LS-SSHRVEVPG-----
--KNSVSPVSEP-SR----MTSDDYDL--SFI-TSAASPTDDRGPKEICQDHLYKGCQQ-
----------SNCNKSHFHLPYRWQVFVDNTWIDFRAMEDIEKAYCDPQNEVI-LMGTHR
INFQKMT-CGSYRIRRLSTPSFVA-QSENSVFST

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

TWLWYWKNELNRYVQYGDESHGHP-R
SN--ISSPYLESLFRSCPRGVVVPFQAGSQSYELSFQ--GMIQTNISSKTQRCVV

ENSGT00760000119084_5_Linker_1_2 (896, 963)

RRP-V
FVSW--KDVEQRRRG-PDW----------QPVMPQAEALT--LDAPPQRNISK--FPSNR
YE

PF00644 // ENSGT00760000119084_5_Domain_2 (963, 1161)

LLELKSYEGEYVKISELFKASMKYHRIVKIKRIWNEQLFQAFERKALLM-GNKTEMRL
FHATSRVHVDYICQNNFERILYGSL-ENRYGKGNYFTKEAISSHKNCPYDA------RNS
VMFVARVLV-GDFTEGNMMYN-SPP------AHYDSCVDSRLNP------------SVFV
IFQKEQIYPE-----YVIEYSEPE---------RDKTCIIS---

MADPEVCCFITKILCAHRGRMDMDALLQEIKLSEEQLCEVLQVAGPDRFVVLETGGVVGV
TRSVVATTR-ARVCRRKYCQS-RCDN-LHLCKLNLLGRCNYSQS-DRNLCKYSHEVLSDD
NFRVLKMHELSGLNQEELKVLLVQSDPFFMPEIC--KSYKGEGRQQICSQQPPCARLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLSPDVVQNIQDICNSKHM--QKNTMG
PRAPT-HRGN-----MAYRARSKSRDRFLQGSQEFLASASASAQRTCTPS-PDQIGHR-A
SLGDVPV---DDLTYKFGYLGSQVH-TRLPSGSSKDTD-LGGTSQAGASRGF-SENGSLH
GILYGNPGDTYHASDS--TPAPSWKGPTSWTNDKGTGRESVFSPTLPATRSSLGCLQTPE
AVTTRKGAGLLSS-DYRNIHGKSGTQDMQ-AGPLFNNNADGVATD-ITSTRSLNCKSTNS
GQR-----------DISSPRNQDA-GPASRH----------------LQATG----RITD
GADPRVAPVNGKYRGKTLWASTFVHDALNGSSKVADKTTDVGKTG--ATGFGLTMA---V
MGEKDMLHGSQSLRSLGPAIPGETAVPA----QVSTLPQSPA-ALSSSNRAAVWGAQGQN
CTQAPVSSASEL-TR----RMTGSAQYSLSDVTSTASSRVDDHGSKEICLDHLYKSCPL-
---------NGSCTKVHFHLPYRWQMFISRTWTDFQFMEKIEEAYCDPQIQLF-SVGSYT
INFRKMT-CGSHPIQRLSTPSSVT-KSGNPVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDNQK-S
SS--IDSSYLEAFYQSCPRGV-VPFQAGSRNYELSFQ--GMIQTNVASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSP--WDVEQMKRG-PDH----------QPAQTSSAPLT--ATFLPRQDLC--FLSSKK
YEVSEINHPHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYVKVSEHFKASMKHFKIEKIKKIQNPELLDCFTRKKSQM-K-VEENLL
FYATKRAYVESICANNFDWTIHETH-ATTYGKGSYFAKDAIYSHKNCPYDA------KNI
-MFVARVLV-GNFTEGNRTYT-SPP------PLFNSCVDTRLNP------------SVFV
IFQKDQIYPQ-----YVIEYTETD-----------KACVIS---

-MAPELCSFITKILCAHK-RMTLEALLGEIVLSEAQLCEVLEVAGPDRFVLLEEGRTTGV
TRSVVAATR-ARVCRRKYCHG-PCEN-LHLCKLN-LGRCHYSHS-ERNTCKYAHD-LSEH
NFRILKNHELSGLNQEELAVLLVQSDPFFLPEIC--KTYKGEGRKQICNQPPPC

PF00642 // ENSGT00760000119084_5_Domain_0 (175, 200)

ERLHI-
CEHFTRGNCGYPNCLRSHNLMDRKVLAIMRE-HGLSPDVVQNIQDICNSKHS--RRNPPG
FRAPPPHHRA-----MPYRGRSKSRDRFFQDSREFFATGFVHAERTCTRS-PDPVGHR-A
SLDNGSV---DDLTHKFTRLGSQES-SQP-SASAKATI-PGGTGEVGASQKL-LKNDSTE
GSFCGKQGKDLLASDP--PQVSTWKGPTSWPREPDTRRDREFSLDEAAARFPPGSVQTPE
A---RKSTGTFS--DRANTGGKSGSEDTQ-PVPLSSKNAIAVTTD-RTAPRSSEYQATTG
TGR-----------EIPSSRRQDAGKTVPQD----------------LQSPD----KMTD
DSRPGGACVN--------------------------------------------------
------------------------------------------------------------
--------------------------DSVSDVTRSTPSRRGEDDSKEICLDYLQKGCEP-
---------SGDCSKIHFHLPYRWQILIANTWTDIPSMENIERAYCDPNTHXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXX-XXX-XXXXXXXXXXXXXXXXXXXXXXXXX--XX-X
XX--XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXMIQTNTASKTQKDVIRRP-R
FVSP--QDVARMKGG-PDQ----------QPAQTQSDSLI--PKLLSQWALS------SG
YKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKSKM-KKKDEKLL
FHAAGRRQVESICVNNFDWVLHECH-ETKYGKGEIFAIGCMY------------------
------------------------------------------------------------
--------------------------------------------

MADPEVCCFITKILCAHGGRMALDALLEEIALSEPQLREVLQVAGPDRFVVLETSGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEVLKESCKGEAGLELLSSSDPPASASQSM
SHCTQRLNFRFPNSCRK-FIIDAKVIAILRSMKGLSPQINI-SSLFLTVKPQ--RKAAFS
PLAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSSHR-A
SLEDTPV---DDLTHKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGASRRF-LENGSQE
DLLHGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTGLPPTLPAALSSLGSLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDVQ-PGPLFNNNADGVATD-VTSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPPSRD----------------VQVTG----RITD
DAGPRVALVNGKYKGKKLGASAFVHDTPNGSSQVADKTTDVEKTG--ATGFGFTMTV--M
VEKDKLRSGSQSLRSLVPTTPGESTAPA----QVSTLPQSPA-ALSSSNRAAVWRAQGQN
CTQLPVSPASEL-TR----KTTGSAQYSLSDVTSTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGSCSKVHFHLPYRWQMFTGKTWTDFKPMEMIEEAYSDPRIHVC-SVGSYT
INFREMS-CDFIPIRRLSTPSSVT-MPANSVFTTKWIWYWKNESGTWIQYGEEKDNQK-S
SN--VDSLYLESLYQSYPRGV-VQFQAGSRNYELSFQ--GMIQTNKASKTQKDVIRRP-K
FVSQ--WDVQQMQRG-PDR----------QPAQTSSVSLT--ANFLPQEDLC--FLSSNK

PF00644 // ENSGT00760000119084_5_Domain_2 (961, 1160)

YKLSEIHHLHPEYVKVNEHFKASMKNFKIEKIKKIENLELLDKFTRKKSQM-K-EEGSLL
FYATSRANVDSICANNFDWALHETH-ETKYGKGSYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYM-SPP------QRYDSCVDTSLNP------------SVFV
IFEKDQIYPQ-----YVIEYTDAD-----------KPCVIS---

MADPGVCCFITKILCAHGGRLALDALLQEIGLPKAQLCHELEAAGLERFVVLETGGKDGV
SCSVVATTP-VRICRRKHCER-PCGK-LHLCKLNVLGRCHYSQA-ERNLCKYSHEVLSEE
NFQVLKSHGLSGLNQEELAVLLIQSDPFFLPEIC--KTYKGEGRKQICSHQPLCERLHI-
CEHFTRGECRYLNCLRSHNLMDRKVLAAMRE-HGLSPDVVQNIQDICNSKHA--KNNAAG
TRAPPPHRRPATPRTAAPRDRSTSKDRPFHGSREFLSSALAS-PRSCTSS-PDGPGLG-P
SPEAAPV---DKLTHRFSGLGTGAG-PLPSSGSATPTE-PRGPMKVGGSQRL-PENGCAA
GAPLRPPSSTDSGRKSSSVQESTRKGSDSA--------------------------PTSE
AGAT--ASACVS--DPQGAGAGSGAAGSP-QASL-SNNAHGGAAY---------------
------------------PTDGAGTGGPFGDPL--------------ALGTS----QRTG
GDDPGVASLTGKYRGSTFRANTATELQPLGPVIRALSTT---------------LRL---
------------------------------------------------------------
-ARV---------SV----SCLSCVTDSVSAVPSATSPRLNDHGSEEICLAHLYGGCQR-
---------DGSCNRVHFHLPYRWQVLILNNWVDFQDMEKIEEAYCDPKNQII-SIGSDK
INFQKMT-CNCNPMRRVSTPSSVT-DPDSSVFTTQWIWYWRSESDRWIPYGEENHNQP-S
SN--IDSSYLESLFQSCRRGI-VQFQAGSRNYELSFPAKGMIQTNIASKTQKGVARRP-A
FVSL--WEVEQMKRI-LDH----------DADTPQGAGVT--GVHRSQEQIC--VYKCPV
FK

PF00644 // ENSGT00760000119084_5_Domain_2 (963, 1161)

LLELSTHSSEYIGISEHFKTSMKNVKIEKIKKIENPRLWNTFQRKKLTM-QDKEEKLL
FYATGRAHVESICANNFDRTLHGPH-ETKYGQGYYFTKDPICAHKNCPFGA------KNT
VMFVARVLT-GSFVEGNMMYT-SPP------VPYDSCVDTRSNP------------SVFV
VFQKEQIYPA-----YVIEYSEVD-----------KACVVS---

MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPLG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDQIGHR-A
SLEDAPV---DDLTRKFTYLGSQDH-ARPPSGSSKATD-LGGTSQAGASQRF-LENGSQE
DLLHGNPGSTYLASNS--TPAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPE
AVTTRKGTGLLSS-DYRIINGKSGTQDIQ-PGPLFNNNADGVATD-IISTRSLNYKSTSS
GQR-----------EISSPRIQDA-GPASRD----------------VQATG----RIAD
DADPRVALVNGKYKGKTLWASTFVHDIPNGSSQVVDKTTDVEKTG--ATGFGLTMAV--K
AEKDMLRTGSQSLRNLVPTTPGESTAPA----QVSTLPQLPA-ALSSSNRAAVWGAQGQN
CTQVPVSSASEL-TR----KTTGSAQYSLSDVTSTTSSRVDDHDSKEICLDHLCKGCPL-
---------NGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEEGYCNPGIHLC-SVGSYT
INFRVMS-CDSFPIRRLSTPSSVT-KPANSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDKRK-N
SN--IDSSYLESLYQSCPRGV-VPFQAGSRNYELSFQ--GMIQTNIASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-T
FVPQ--WYVQQMKRG-PDH----------QPAKTSSVSLT--ATFHPQEDFC--CLSSKK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYIRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM-K-GEGKLL
FYATSRAYVESICANNFDCFLHETH-ENKYGKGIYFAKDAIYSHKNCPYDA------KNV
VMFVAQVLV-GKFIEGNITYT-SPP------PQFDSCVDTRLNP------------SVFV
IFQKDQVYPQ-----YVIEYTE-D-----------KACVIS---

MADPEVCCFITKILCAHGGRMALDALLQEIALSKAQLCEVLKAAGPNRFAVLETRDGAGV
TRSVVATTG-ARICRRKFCKK-GCGN-LHLCKLNLLGRCHYSQS-DRNLCKYSHDVLSEE
NFKILKQHELSGLNKEELTVLLVQSDPFFLPEIC--KNYKGEGRRQICNQQSPCERLHI-
CEHFTQGNCGYANCIRSHNLMDRKVLAIMRE-YGLSPEVVQNIQDICNNKHN--LRKPYG
LRAPPSQRRD-----RAHGGRSKSKDRFYRGSLEFLPSASSSADRSGTSS-PDQSGRS--
PL---DA---VDLTHKFLRLXXXXX-XXXXXXXXXXXX-XXXXXXXXXXXXX-XXXXXXX
XXXXXXXX------XX--X-----------------------------XXXXXXXXXXXX
XXXXXXXXXXXXX-XXXXXXXXXXXXXXX---------XXXXXXX-XXXX--XXXXX---
XXX-----------XXXXXXXXXX----XXX----------------XXXXX----XXXX
-XXXXXXXXXXXXXX--X------------------XX----XXX--XXXXXXXXXX---
--------------------------------------------------XXXXXXXXXX
XXXXXXXXXXXX-XX----XXXXXXXXSVSDAASTASSGMDDHDSKEICLDHLNKGCLL-
----------NDCNKVHFVLPYRWQMLNASTWVDLQPMENIEKAYCDPKNSVI-SLGNYR
IDFKKMT-CNFNPIRRLSTPSSVQ-IPNGLTFATKWIWYWKSESDTWVQYGKEVGNQQ-I
SN--IDSSYLESFFLLYPRGI-VPFQAGSRNYELSFQ--GMIQTNVASKTQKDVIRRP-E
FVSA--QDVARMKSG-PDS----------QPAQTQLETLT--SAFLPQVDFS--FPSSN

PF00644 // ENSGT00760000119084_5_Domain_2 (960, 1162)

R
YQLLELNNQHPEYVRISEYFKVSMKNVKIEKIKKIKNTQLWDAFERKKMKM-K-EERKML
FYATCRANVDFICANNFDWASHGTV-ETKYGKGNYFSKDAIYFHKNCQYDP------KNI
VMFVARVLV-GDFIEGKMSYT-SPP------PLYDSCVDTRFNP------------SVFV
IFQKDQIYPE-----YVIEYTEAD-----------KACVIS---

MADPEVCCFITKILCAHGGRMALDALLEEIALFEPQLCEVLQVAGPDRFVVLETSGEAGI
TRSVVATTR-ARVCRRKYCQR-PCEN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CEHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSSHR-A
SLEDTPV---DDLTHKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGASRRF-LENGSQE
DLLHGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTGYPPMLPAALSSLGSLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDVQ-PGPLFNNNADGVATD-TTSTRSLNYKSTSS
SQR-----------EISTPKTQDA-GPASRD----------------VQATG----RITD
DAGPRVALVNGKYKGKKPGASAFVYDTPNGSSQVADKTTDVEKTD--ATGFGFTMTV--M
VEKDKLRSGSQSLRSLVPTTPGESTASA----QVSTLPQSPA-ALSSSNRAAVWRAQGQN
CTQVPVSPASEL-TR----KTTGCAQYSLSDVTSTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGSCSKVHFHLPYRWQMFIGETWTDLKPMEMIEEAYSDPRIHVC-SVGSYT
INFREMS-CDFIPIRRLSTPSSVT-KPA-SVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 891)

KWIWYWKNESGTWIQYGEEKDNQK-S
SN--IKKKKKKSLYQSYPRGV-VQFQAGSRNYELSFQ--GMIQTNKASKT

ENSGT00760000119084_5_Linker_1_2 (891, 976)

QKKKKKRP-K
FVSE--WDVQQMKRG-PDR----------QPAQTSSVSLT--ATFLPQEKKK--KKTSNK
YKLSEIHHLHPEKKK

PF00644 // ENSGT00760000119084_5_Domain_2 (976, 1160)

KKKHFKASMKNFKIEKIKKIENLELLDKFTRKKSQL-K-EEESLL
FYATSRAYVESICANNFDWALHETH-ETKYGKGSYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYM-SPP------QQYNSCVDTRLNP------------SVFV
IFEKKKKKTQ-----YVIEYTDAD-----------KPCEKKKKK

MADPGVCSFITKILCAHGGRMALEALLREMQLSEAQLCEVLEEAGPDRFVVLPGSGREGL
TGNRISNIRDVNICLMKYRHS-LYGSGVYVYKLRSLNLCHAVQKEYMNLCKYSHEVLSED
NFRVLTNHGLSGLNQEELAVLLLQSDPFFMPEIC--KNYKGEGGRQICNQQPPCERLHV-
CEHFTRGNCGYANCFRSHNLMDRRVLAVMRE-HGLSSSVVQNIQDICNSRHR--RKKPSA
WKAPPPHRRD-----PAYRGRSRSRDR---GGEEFLPAASTPAQRSCSAS-PEPAGHHGS
VPSDGPV---EDLAHKLSHLGSQEC-PPPASVPSAAVV-LGGTHQGGGSQKL-AENGSAK
DLFYGNHS------DL--TPAFNWKGPASWQNDQDTGKKSWLSSSPAFSFSPPGSPQTPE
TITTRNSTAVLSS-DHVNAECRSGNQDSQ-HFPLFDNKADGMAVD-TTSTRLANYQTPSS
SQR-----------EKSLPRNPDT-GTPRSH----------------LPTAG----KMT-
-GDGASAFVN--------------------------------------------------
------------------------------------------------------------
--------------------------DSVPEAASTTSSRMKEHSSNEICLDHLYKSCQL-
----------KSCNKVHFHLPYRWQMLLGNSWVDLPFMEDIEKAFCDPKNCSV-SVGNYN
ISFQKMI-CDFNPVRRISTPSSVT-KPASSLFTTKWIWYWRNETDEWVPYGEKKDNEH-I
SS--IDSSYLESLFLSCRRGV-VPFQAGSRNYELSFQ--GMIQTNIASKTQKDVIRRP-T
FVSY--WDVERVKRR-QDP----------QQGQTSSEPFV--TIYLPQPDAS--VSVSNS
FELLE

PF00644 // ENSGT00760000119084_5_Domain_2 (966, 1161)

IPNNTPEYAKVSDHFKASMRNFKIEKIKKVQNSQLLKAFKSKKMEM-K-REEQIL
FCAARRSNVASICENNFDWFLHGSP-DTKYGKGNYFTRDAISSHKYYPFDS------KNI
VMFVARVLV-GNFIEGHMGYQ-SPP------PRYDSCVDTRLNP------------SVFV
IFQKDQIYPE-----YVIEYTELE-----KSEKTEKPCVIS---

MADPEVCCFITKILCAHGGRMALDALLQEIALSEAQLREVLEAAGPDRFVLLETGDRAGV
TRAVVAATR-ARVCRRKFCQR-PCED-LHLCKLNLLGRCHYSQA-ERNLCKYSHEVLSEE
NFKVLKNHELSGLNKEELAVLLIQSDPFFLPEIC--KNYKGEGRRVICDKYPQCERLHI-
CEHFTRGNCGYANCLRSHNLMDRRVLAIMRE-HGLSPSVVQNIQDIFNNKHS--RKKHSG
YRAPPSYRRD-----KAYRGRSKSRDRSFQGSTEFLPSAPAPAQKSCSSS-PDPVGHR-P
PLDNVPV---EDLAHKFGRLGSQDC-PQPSPVSPKANS-LRGAGQVGGSRRF-SENGSPE
DLFYGHQDSIFFPSDS--TPASNRKGPDSGLNDKGTSRESVFSWSKATSGS-VGSLQTPE
TITTRKSTGLLSP-DGMSAEARGSNQNAQ-YFPLFNNNVDGMATD-GTSARSLNYKTTTR
GQR-----------EKSLPRNQDA-GTPPGN----------------VQTTG----TIMG
GDDPAAAPANGK--VKPPWASKSVHGIPDGSSQVVGGS----------------------
---PPVSIGSQNLYTLVLPTPQETTVPTV---QVRTRFEMPLSMSSSGTRAAAYASHGQN
SAQTPVSPASEF-AR-----TPRCAPYSAFDVGSTSSSRMDDCDPQEICLDHLCKGCQTV
---------SENCNKVHFHLPYRWQMFFANTWMDLQPMENIEKAYCDPQIRIF-SIGNKS
IDFQKMT-CNSIPIRRISTPSSVT-TLTNFVFATKWIWYWKKESDIWVQYGEEAGNQE-A
SN--IDSSYLESFFLLYPRGI-VPFQAGSRNYELSFI--GMIQTNVASKTQKDVVRRP-T
FMSY--KDVEQIKSN---Y----------QLMQTLSEPLI--STLPPQPDFS--LNGY

PF00644 // ENSGT00760000119084_5_Domain_2 (959, 1161)

EL
V---EINNQNPEYVMISESFKASMKNFKIENIKKIKNTKLLNAFERKKLKM-NNRTEKIL
FCATRRTYVESICKDNFNWIIHGSS-DTKYGKGIYFTKDAIYSHKDQQDDT------KNM
VMFVARVLV-GDFTQGYRESLNPPP------PPYDSYVDVRLNP------------SIFV
IYEKDQIYPQ-----YVIEYTEPE-----------KACVIS---

MTDPEVFCFITKILCAHGGRMTLEELLGEISLPEAQLYELLKAAGPDRFVLLETGDQAGI
TRSVVATTR-ARVCRRKYCQR-PCDS-LHLCKLNLLGRCHYAQS-QRNLCKYSHDVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICGQPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMRE-HGLSSDVVQNIQDICNNKHT--RRNPPS
MRAPHPHRRG-----GAHRDRSKSRDRFHHNSLEVLST-VSP-LGSGPPS-PDVTGCK-D
PLEDVSA----DVTQKFKYLGTQDR-AQLSSVSSKAAG-VRGPSQMRASQEFL-EDGDPD
GLFSRNRSDSSTSRT-------------------------------SAAGFPLVAAQRNE
AGAMKMG--MPSG-HHVEVKGKN--EDID-RVPFLNSYIDGVTMEEATVSGILGKRATDN
GLE-----------EMILSSNHQKSVAKTQD----------------PQTAG----RITD
-SGQDTAFLHSKYEENPAWPGTSTHNGPNGFSQIMDETPNVSKSS--PTGFGIKSAV--T
GGKEAVYSGVQSLRSHVLAMPGETTTPVQ---GSNRLPPSPL-SSSTSHRVAASGSPGKS
STHASVSPASEP-SRMM-MMMSDPAEYSLCYIVNPVSPRMDDHGLKEICLDHLYRGCQQ-
----------VNCNKNHFHLPYRWQLFILPTWMDFQDMEYIERAYCDPQIEII-VIEKHR
INFKKMT-CDSYPIRRLSTPSFVE-KTLNSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWLWYWRNELNEYTQYGHESPSHT-S
SE--INSAYLESFFHSCPRGV-LQFHAGSQNYELSFQ--GMIQTNIASKTQRHVV

ENSGT00760000119084_5_Linker_1_2 (896, 971)

RRP-V
FVSS--KDVEQKRRG-PDH----------QPVMPQADALT--LFSSPQRNAST--VSSNE
YEFIELNNQD

PF00644 // ENSGT00760000119084_5_Domain_2 (971, 1115)

EEYAKISEQFKASMKQFKIVTIKRIWNQKLWDTFERKKQKM-KNKTEMFL
FHAVGRIHMDYICKNNFEWILHGNR-EIRYGKGNYFTKEAMYSHKSCSYDS------RGT
VMFVARVLV-GSVIEGNMTLS-SPP------ALYDSCVDTRLNP------------SVFV
IFRKEQIYPE-----YVIEYMELE---------KEKGCIIS---

MTDPEVFCFITKILCAHGGRMTLEELLGEISLPEAQLYELLKAAGPDRFVLLETGDQAGI
TRSVVATTR-ARVCRRKYCQR-PCDS-LHLCKLNLLGRCHYAQS-QRNLCKYSHDVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICGQPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMRE-HGLSSDVVQNIQDICNNKHT--RRNPPS
MRAPHPHRRG-----GAHRDRSKSRDRFHHNSLEVLST-VSP-LGSGPPS-PDVTGCK-D
SLEDVSA----DVTQKFKYLGTQER-AQLSSVSSKAAG-VRGPSQMRASQEFL-EDGDPD
GLFSRNRSDSSTSRT-------------------------------SAAGFPLVAAQRNE
AGAMKMG--MPSG-HHVEVKGKN--EDID-RVPFLNSYVDGVTMEEATVSGILGKRATDN
GLE-----------EMILSSNHQKSVAKTQD----------------PQTAG----RITD
-SGQDTAFLHSKYEENPAWPGTSTHNSPNSFSHIMDETPNVSKSS--PTGFGIKSAV--T
GGKEAVYSGVQSLRSHVLAMPGETTTPVQ---GSNRLPPSPL-SSSTSHRIAASGSPGKN
SAHASVSPASEP-SRMM--MMSDPAEYSLCYIVNPVTPRMDDHGLKEICLDHLYRGCQQ-
----------VNCNKNHFHLPYRWQLFILPTWMDFQDMEYIERAYCDPQIEII-VIEKHR
INFKKMT-CDSYPIRRLSTPSFVE-KTLNSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWLWYWRNELNEYTQYGHESPGHT-S
SE--INSAYLESFFHSCPRGV-LQFHAGSQNYELSFQ--GMIQTNIASKTQRHVV

ENSGT00760000119084_5_Linker_1_2 (896, 962)

RRP-V
FVSS--KDVEQKRRG-PDH----------QPVMPQADALT--LFSSPQRNTST--VSPNE
Y

PF00644 // ENSGT00760000119084_5_Domain_2 (962, 1112)

EFIELNSQDEEYAKISEQFKASMKQFKIVTIKRIWNQKLWDTFERKKQKM-KNKTEMFL
FHAVGRIHMDYICKNNFEWILHGNR-ETRYGKGNYFTKEAMYSHKSCSYDS------RGT
VMFVARVLV-GSVIEGNMTLS-SPP------ALYDSCVDTRLNP------------SVFV
IFRKEQIYPE-----YVIEYMELE---------KEKGCIIS---

MTDPEVCCFITKILCAHGGRMALDKLLEEIALSEAQLCEVLEKAGPDRFVVLETGGRAGV
SRSVVANTR-ARVCRRKFCDR-PCEN-LHLCKLNLLGRCGYSHS-DRNLCKYSHDILSEK
NFRVLKNHELSGLNQEELAVLLIQSDPFFMPEIC--KSYKGAGRGQICNQQPSCERLHI-
CEHFTRGACRYSNCLRSHNLMDRNVLTIMRR-HGLSLEVIHNIQDICNSKHAPGRKNPSV
WRAVSPNHRG-----MAYRSRSKSRDRLSQDNQEFLPSASASTQRSYTPS-PDDNGGM-S
PLDD--I---KDLTDKFMNFGSQDS-SQPSSVSSKAPS-LGGTS-----HKV-SVNDGVE
GLLFGNP---YSASDS--TSASSWKGSTSWLNHQGTERETLFSKNQAASFTDFVSVQTKS
T-------GRPSLDLSPNIEGKSGNKDAQ-HFPLNDDIVDGTATG-TTSIRSLNYNS---
RQR-----------EKSLSRNQGT-RTTDGN----------------LQITG----KTAE
-DDPGLAFFNHKSVGKTYWAN---------------------------------------
------------------------------------------------------------
---------------------------SISDIVDTTSPRTDDCGSEEICLDCLYKGCGL-
----------SNCSKVHFHLPYRWQMLTTNTWMDLRLMEMIEEAYCDPKNWLI-SIRNLN
IDFRKMT-CNANPMRRISTPSSMA-KPVDSIFSTKWIWYWKDKSNNWLQYGKD----Q-T
SN--ISSSYLESLFLSCPRGI-VPFKEGSQNYELSFQ--GMIQTNVVSKTQSDVVRRP-K
FVSS--EDVEHIKKR-LDS----------KPAQTQRKSLT--STFPPQWDFD--RPSISG
YELL

PF00644 // ENSGT00760000119084_5_Domain_2 (965, 1161)

EINDRTTEYAKISAHFKASMKNFKIEKIKKIQNPELLRTFERKKSKM-KTSNEKIL
FYATDRAHLEYICANNFDWTYHGPC-ETKYGKGNYFRTDALCSHKSCEHEA------KNT
AMFVAQVLV-GDFTEGNMMYIRPPLKADDQGTLYDSCVDEMANP------------SVFV
IFQKDQIYPA-----YVIEYTEIG-----------KTCLIS---

------------------------------------------------------------
-----------------------------------------------NLCKYSHEILSED
NFKVLKNHALSGLNKEELAVLLLQNDPF-MPEIC--KNYKGEGGRQICNQQPPCERLHV-
CEHFTRGNCGYANCFRSHNLMDRKVLAIMRE-HGLSSRVVQNIQDICNSRHR--QKKPSG
RRAPPSHRRD-----AAHRGRSKSRDR---GSGDSFPSAAASAQRSCPPS-PDPTG-RGS
PPDDGPV---KDLAHKFTHLGSQEC-PPPSSGSSAASN-LGGTGQRGASQRF-AENGSPE
DLFYGNHSNTYVTFDS--TSSPKWKGPASWQNDQDTGRESLFSSSQAVSFSPLGSPQIPE
TVTTRKSTAILSS-DCVNTEGRRGNQDSQ-HFPLFNNNVDDMATD-ATSMRLLNHKTTAS
RQR-----------EKSLPRGQDT-GVTRSH----------------LQPAG----QMTA
ANDGATAFVN--------------------------------------------------
------------------------------------------------------------
--------------------------DSVSDVASTECSTRDEHGSNEICLDHLYKGCQL-
---------SERCNKVHFHLPYRWQM-TGKIWMDLPFMEDVEKAFCDPQVCNI-SIGNYK
ISFQKMT-CDYKPIRRLSTPSSVT-MPAGSLFTTKWIWYWRNGYDKWVQYGEKKDNEH-I
SN--IDSSYLESLFLSCRRGI-VPFQAGSQNYELSFQ--GMIQTNIASKTQKDIVRRP-T
FVSY--WDVEQVKHG-QVH----------QQVRTQPEPFT--SVFSPQRGTC--TSSS

PF00644 // ENSGT00760000119084_5_Domain_2 (959, 1162)

TG
YELFEINNDSLEYAKVSEHFKASMKNFKIEKIKKIRNAKLLKAFERKKKEM-K-RDERIL
FCAVRRTHVESVCANNFDWVIHGIC-DTKYGKGNYFTKDAINSHKNCLCDP------KNI
VMFVARVLV-GDFIEGHKAYM-SPP------LRYDSCVDTRLNP------------SVFV
IPQKDQIYPE-----YVIEYTETD-----------KACVIS---

MADPGVCCFITKILCAHGGRMTLEELLGEIRLPEAQLYELLETAGPDRFVLLETGGQAGI
TRSVVATTR-ARVCRRKYCQR-PCDS-LHLCKLNLLGRCHYAQS-QRNLCKYSHDVLSEQ
NFQILKNHELSGLNQEELACLLVQSDPFFLPEIC--KSYKGEGRKQTCGQPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLTIMRE-HGLSPDVVQNIQDICNNKHA--RRNPPG
TRAAHPHRRG-----GAHRDRSKSRDRFLHNSLEFLSPVVSP-LGSGPPS-PDVTSCK-D
SLEDVSV----DVTQKFKYLGTHDR-AQLSPVSSKAAG-VQGPSQMRASQEF-SEDGNLD
DIFSRNRSDSSSSRA-------------------------------SAAK----VAQRNE
AVAMKMG--MEV-----KGKKEA--PDID-RVPFLNSYIDGVTMEKASVSGIPGKKFTAN
DLE-----------NLLLLNDTWKNVAKPQD----------------LQTTG----RITD
-SGQDKAFLQSKYGGNPVWASASTHNAPNGSSQIMDETPNVSKSS--TSGFAIKPAI--A
GGKEAVYSGVQSPRSQVLAMPGETTTPVQ----SNRLPQSPL-SS-SSHRAAASGSPGKN
STHTSVSPAIES-SR----MTSDPDEYLLRYILNPLF-RMDNHGPKEICQDHLYKGCQQ-
----------SHCDRSHFHLPYRWQMFVYTTWRDFQDMESIEQAYCDPHVELI-LIENHQ
INFQKMT-CDSYPIRRLSTPSYEE-KPLSAVFAT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNEFNEYIQYGNESPGHT-S
SD--INSAYLESFFQSCPRGV-LPFQAGSQKYELSFQ--GMIQTNIASKTQRHVV

ENSGT00760000119084_5_Linker_1_2 (896, 965)

RRP-V
FVSS--NDVEQKRRA-PDH----------QPVTPKADALN----SIPQKNAST--VLPNE
YEFL

PF00644 // ENSGT00760000119084_5_Domain_2 (965, 1095)

ELNDQDVEYVTVSEQFKASMKPFKIVRIKRIWNQKLWDAFERKKEKM-KNKNEMLL
FHAACRAHVDYICKNNFEWILHGSR-ETRYGKGNYFAKEAIYSHKNCSYDI------RNI
VMFVARVLV-GNVIEGNMTFS-SPP------ALYDSCVDTRLNP------------SVFV
IFRKEQIYPE-----YLIEYVESE---------KEKGCIIS---

MADPGVCSFITKILCAHGGRMTLEELLGKIALPEAQLWELLEAAGPDRFVLLELGGRAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCHYSQA-DRNLCKYSHEVLSEQ
NFQVLKNHELSGLNKEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICSEPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMKE-HGLSPDVVQSIQDICNSKHI--RRNPPG
SRPPNSHRRA-----AASRGRSKSRDRFLQSSLEFLPS-SSS-QRSGPPS-PDVASCE-A
PLEDVQTDDINDLINKIKYLGSQDC-AQPSSISSKAAG-LRVSTQMGKSQKF-SENGGPD
GFSYKNHSNSSLSQR--------------------------------PTSSSLDSAHISE
AITIRKG--VPSS-QHMDVKGKSESQNIQ-YVPLFTGHADGATVA-GTATAALNYRATAN
GPR-----------EMALPSNHQSSAAVLWD----------------LQTTG----RITN
-SDPDLTFLNGKYKENTLRAGKCIHN-SNGSSQIMDKTSKGAKSN--TSGFGLKAAV--T
GENNALCSGGQSLKSQVMTTAGETTALVQ---V-SRLPQSPP-PS-SSHRAAASGTPGKS
LAHASVGPASEL-ARTTPV-------------CISIPTRMDDHDSKEICPDHLYKGCQL-
----------SNCSKIHFHLPYRWQMFI-STWVDFQDMENIEQAYCNPQTDTF-LTGIYE
INFQKMT-FGSNPVRRLSTPSSVT-KPVNSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWLWYWKNESNKWIQYGGE----P-S
SD--IDSSYLESFFQSWPRGV-VPFRVGSQDYELSFQ--GMIQTNVTSKTQRDVI

ENSGT00760000119084_5_Linker_1_2 (896, 965)

RRP-V
FISL--KDMEQLRRG-PDY----------QPVVTNTQALA--SNSLSQRISVN--FQSNE
YEVF

PF00644 // ENSGT00760000119084_5_Domain_2 (965, 1161)

ELNSQDEEYIRISEQFKTSMKQFKIEKMKRIWNQKLSDAFQRKKLRM-RNKEEVLL
FHATRHAYVDYICKNNFECALHESR-ETRYGKGIYFAKEAIYSHKNCPYDA------RNI
VMFVARVLV-GDFIEGNKMYT-SLP------SLYDSCVDTRLNP------------SVFV
IFEKDQIYPA-----YMIEYSDT-----------DKACVIS---

MADPTVCCFVTKILCAHGGRLSLDALLEKIELSEAQLLEVLKEAGPDRFVVLETGGRAGV
TRSVVATTR-ARVCRRKFCERSSCDN-LHLCKLNLLGRCHYSQS-ERNLCKYSHDVLSEK
NFQVLKNHELSGLNQEQLAVLLLQSDPFFMPEIC--KSYKGEGRKQICNQQPPCERLHI-
CEHFTRGNCSYPNCLRSHNLMDRKVLAIMRD-HGLSPAVVQNIQDICNNKHM--RRNPPG
SKTP-VHRRA-----RAARGRSKSRDRVSQDIKEFLPSAS--AHKSGTPS-PDGTDSR-A
SLEDDPM---DDLIHKFEFLETPDC-TQPSSVSSKAAG-LGRPGQVGTSQRF-LENGIPD
GLFHSNQSH--LASNS--TPASNQKGSPSWLNAQGTGKESEFFPSQAVPSFPLDSTQTLK
ALNSRKVVGMLSS-DHMNVKDKSGSQDIQ-RIPIFSRNADGVAMN-------MNFGKT--
AQR-----------EMALSSYQD-SRATPRD-----------------LHIG----SIAS
-DDARVAFLND-------------------------------------------------
------------------------------------------------------------
---------------------------SISDITNTT-SRMGNLGPEGICVDYLHNRCQP-
---------NSDCSKIHFPLPYRWQVLMSHTWKDLEDMEKIEKAYCNPRSHVL-SIENHI
LDFQKMT-YALKPIRRISSPSSGM-NQASTVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWENESGEWIQYGKGSNNQP-G
SN--IDSSYLESFFQKCPRGV-VPFQAGTRNYELSFQ--GMIQTNIASKTQKNVV

ENSGT00760000119084_5_Linker_1_2 (896, 961)

RRP-E
FVSA--RDVEQMRRG-PDPQRVQFSASSPQPVHTPPEAVG--STFVPQWDVL--SPTSSG

PF00644 // ENSGT00760000119084_5_Domain_2 (961, 1117)

YKLLDLDNQSLEYATIRDNFKESMKNFKIEKIKKIHNPELLNSFERRRLNM-TEKRERLL
FYATSRTHVDSICANNFMWNLHGTH-ENKYGKGNHFSKDAIYSHKNCLYDA------RNI
VMFVARVLA-GDFIEGNMTFV-SPP------PPYNSCVDTMLNP------------SVFV
IFRNDQAGFCQKQTVYLEDESKTLVGNKEDSHGKE---------

MADPTVCCFITKILCAHGGRLSLDALLEKIQLSEAQLLEVLKEAGPDRFVVLETGGRAGV
TRSVVATTR-ARVCRRKFCDR-PCEN-LHLCKLNLLGRCHYSQS-ERNLCKYSHEVLSEP
NFRVLKNHELSGLNQEQLAVLLVQSDPFFMPEIC--KSYKGEGRKQICNQQPPCERLHI-
CEHFTRGNCSYPNCLRSHNLMDRKVLAIMRD-HGLSPDVVQNIQDICNSKHM--RRNPSV
PKLP-G-RRN-----IPGRGRSKSRDRASQDVKEFLPSPS--AHKPSDHN-SDGTSSR-A
TLGDRLA---DDITHKLTFIENEDP-AQLSSVSSKAAD-LGGPGQVGANQRF-SENGLPD
SLFYSNRSN--PTSNS--TPVSNQKGSPSWLNAQATRKESVFFPSPGVPASLPDITQTPK
ALTSRMPMGMLSS-DHVDIKAKSGTPDTQ-QVPLFNNN-LGLGMN-------MNFGTTSN
GQR-----------ETALLSYQDS--RTTLD-----------------HKIG----NITN
-DDPGVAFLND-------------------------------------------------
------------------------------------------------------------
---------------------------SGSDVTSTT-SRMGCHGAQDICIDYLRNCCQF-
---------NSSCSKIHFHLPYQWQLLMTHTWVDFQDMEKIEKAYCDPRNVII-SVGNHT
LDFQKMT-CGLRPIRRISTPSSGL-NLANSVFAT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNELGNWIQYGERSNNQP-G
SD--VDSSYLESFFQSCPRGV-VPFQAGVRNYELSFQ--GMIQTNIVSKTQKDVV

ENSGT00760000119084_5_Linker_1_2 (896, 961)

RRP-T
FVSS--LDVEQMRRR-PDPPRVQFSASSRQPAQTPPEAVL--STFVPQRDVG--SLPLNG

PF00644 // ENSGT00760000119084_5_Domain_2 (961, 1161)

YKLIDLSNDSMEYTMIRDCFKESMKNFKIEKIKKIHNPELLNSFERRRLLM-TEKKERLL
FYATSSTHVDSICANNFVWTYDGAQ-TKKYGQGNHFSKEAIYSHKNCLYDA------RNI
VMFVARVLA-GDFIEGNMIYK-SPP------PPYNSCVDTMLNP------------SVFV
IFQKDQIYPA-----YLIEYTET---DKE------KSCVIS---

------------------------------------------------------------
------------------------------------------MFSSRNLCKYSHEVLSEK
NFQVLKNHELSGLNQEQLAVLLLQSDPFFMPEIC--KSYKGEGRKQICSQQPPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMKE-HGLSPDVVQNIQDICNNKHA--RRNPSG
PRAPTPHRRA-----GMTRGRSKSRDRFLPESQEFPPSASAAAQNSRTSS-PDVVGQR-L
FLKDVGV---GDLTYRFTYLGSQDR-TPPSSLLSKAPG-LGGPGQVGSSQKF-SENGSSD
RLFYRNHS------DS--TPSSSQKGSPTWQNDQGPRRDNVFFPGQASGGSPLGLGKTPE
TVTTRKSTAILSP-DLVNVKGQNGTQDTQRHVPLFNNNYDGATMD-ITSARFLNHGTTTG
SQR-----------EMAVARNQQGNGTAPQD----------------VHTTA----RMRN
--DPGVAFCN--------------------------------------------------
------------------------------------------------------------
--------------------------DSILDVV-STSSRMDDHGSKEICLDYLHKSCQL-
---------NSLCNKIHFLLPYRWQIFNSDTWMDIPYMEKLEEAYCDPKTHIF-FVGNDK
INFENMT-CNSSPIQRLSTPSSVT-TLANSVFAT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWVWYWKNESDQWIEYGEESNNQP-G
SN--IDSTYLESMFQSYPRGV-VPFQAGSRNYELNFQ--GMIQTNIISKTQKDVV

ENSGT00760000119084_5_Linker_1_2 (896, 960)

RRP-T
LFSS--QDTKQMRRE-PDH----------QVAQTAAEALTMSSKSLPQPDLG--SHPPS

PF00644 // ENSGT00760000119084_5_Domain_2 (960, 1161)

K
YKLEELDSLSAEYANISDYFKASMKNFKIERIKKIHNQELEKNFERKKSEM-Q-TEEKLL
FYATSRTNVDYICSYNFNWSVHGLH-EIKYGKGNHFAKEAFSSHKNCQDDV------KSL
VMFVARVLV-GNVAEGRMTYR-MPP------PRSDSCVDNTVNP------------SVFV
IFHKDQMYPA-----YVIEYTEMD-----------KACVIC---

MADPEVCCFITKILCAHGGRMALDALLEEIALSEPQLCEVLQVAGPDRFVVLETSGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKKHELSGLNKEELAVLLLQSDPFFMPEIC--KIYKGEGRQQICNQQPPCSRLHI-
CEHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSSHR-A
SLEDTPV---DDLTHKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGASRRF-LENGSQE
DLLHGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTGFPPTLPAALSSLGSLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDVQ-PGPLFNNNADGVATD-TTSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPASRD----------------VQATS----RITD
DAGPRVALVNGKYKGKKLGASAFVHDTPNGSSQVADKTTDVEKTDAEKTGFGFTMTV--M
VEKDKLRSGSQSLRSLVPTTPGESTASA----QVSTLPQSPA-ALSSSNRAAVWRTQGQN
CTQVPVSPASEL-TR----KTTGSAQYSLSDVTSTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGSCSKVHFHLPYRWQMFIGETWTDFKPMEMIEEAYSDPRIHVC-SVGSYT
INFREMS-CDFIPIRRLSTPSSVT-KPA-SVFAT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDNQK-S
SN--IDSLYLESLYQSYPRGV-VQFQAGSRNYELSFQ--GMIQTNKASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSQ--WDVQQMKRG-PDR----------QPAQTSSVSLT--ATFLPQEDLC--FLSSNK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1160)

EYVKVSEHFKASMKNFKIEKIKKIENLELLDKFTRKKSQL-K-EEESLL
FYATSRAYVESICANNFDWALHETH-ETKYGKGSYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYM-SPP------QQYNSCVDTRLNP------------SVFV
IFEKDQIYPQ-----YVIEYTDAD-----------KPCVIS---

MADPTVCDFLTRILCAHGGRMELRELLGHIELSETQVVEVLSEAGPERFMLLDQGP--GT
CPVVLATTS-VRVCRRKVCEG-QCEA-LHLCKLNLLDRELNYATSFWIYCKYSHD-ISEK
NIRILKKHSLFTLSKKELGVLLLQSDPFFLPDIC--KHYKGENRSDSCSKKTECQRLHI-
CEHFTQGKCGFEHCNRSHNLMDTKALELLRE-HGLTDSIIMNIQDIYNQKHAK-NKNPPR
QEASASHKTP--LPLPAGRNRSQSRNRYFFETQELAPSPSALVGTSHIPG-PDKTTPA--
PLPSFEG----KAKESRTTTLSKDC-AQSVSVSPKTSK-TQEGCQAGTNSNV-SVTSHRE
SRF-GNQDGTQLAA-STSPPFSTDKGSTPVRSSRVERKINMFFGSEDDS------FSGPD
LITTSKSGVMPSH-NCANAGDDFGNQKAY-SSPGLPKTVHVQGKG-SNPVVFSKYKQTAN
GKK-----------EDSSCKSKDN-QSTLANPQMAKT----------ATSIGKLATPI--
-PNHSVANVSSTVRSRTFWNTHEQQHNLN---KLADESLACQ-----TDALNLNSAIIAK
KDRKDASCASQNIQAL--PVSNTATASGPPKTSSASLTQSGI--QKCNLRMFSFGQVGSV
SSSGSCQTS-----DTLTASNSGGASPSKTRVSNTTPSEMESNDSTEICLDFLHTDCKL-
---------QERCKNIHFHLPYRWQLRIANNWKDFKDMEDIEKAYCDPNISQ-----SHS
IDFQKMT-FGYFSVRRLSTPSTIQ--KPDYALSTE

PF02825 // ENSGT00760000119084_5_Domain_1 (816, 896)

WLWYWKDELDQWIEYGKEVEKLK-S
YSFENNSRDLEVFSQIYPMGT-MEFKAGHHSYLLNFK--EMIQTNILYHTKREVR

ENSGT00760000119084_5_Linker_1_2 (896, 963)

RRP-K
FVGFPHWRIFYLKKF-PSR----------WNILEASVPLTVVPL-SCQNAFLIGFFFLFF
FK

PF00644 // ENSGT00760000119084_5_Domain_2 (963, 1098)

LLEVSRMSNEYVVIDFRFKSTMKNFEIQKIMRNQNPSLWNKFQRKKKMMLSNGEEKIL
FHATDQTRITSICTFSFDYSYQSLH-EAKYGKGIYFAKEASSSHNNHKSSA------KKK
IMFVAQVLV-GIMAEGKETHR----------PPELTIVDNINNP------------SIFV
IFDSHQVYPE-----YVIEYTDID-----------KACSIS---

------------------------------------------------------------
-----ATTR-ARVCRRKYCDR-PCEN-LHLCKLNLLGRCHYSQS-ERNLCKYSHDVLSEE
NFKVLKNHELSGLNKEELRVLLVQNDPFFLPEIC--KHYKGEGGRQICKQQPPCERLHV-
CEHFTRGDCGYANCFRSHNLMDRKVLVIMKE-HGLSSSVVQNIQDICNSRHS--RKKSSG
WKAPSSHRRD-----VPYTGRSKSRNRLLQGTLEFLPSASASAQRSCTPS-PEPVGRK-P
SLDDVLM---EAVTHKFVHLGSQDC-SQPAPVSSMAVS-FGGTGQVGGSQRF-SENGGPE
SLFHGNHDRKGITLDS--APASKWKGPTSWQKDQDTSRESLFPLRQAVST-SAGSPQTPE
TLTTRKSPAVLSL-DCGNTENKSEIPA---VLPCRFNNVDGMAPD-GTSAKPSNYKTTTS
RQR-----------EKSLPRNQDT-GTTHHN----------------VQTPG----KITA
DDV-GAAFVN--------------------------------------------------
------------------------------------------------------------
--------------------------DSVSDVASTASSRMDERGSNEICLYHLYKGCQL-
----------NGCHKVHFHLPYRWQMFIGNTWMDLLLMENIEKAFCDPKICVI-TIGNYK
I-FRKMXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXXXXX-XX-X
XX--XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX-XXM

PF00644 // ENSGT00760000119084_5_Domain_2 (882, 1162)

IQTNVASKSQKDVVRRP-T
FVSY--SDVEQIKRG-RDH----------QQMQTQSEPLT--STFVPQQNRSF-SNDYKX
XXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXRRKEM-Q-RYEKLL
FCATAQAHVESICANNFDWTVHGVH-DAKYGKGNYFTMEAINSHKNCPYGL------KNI
VMFVARVLV-GEFTEGRMSYT-SPP------PHYDSCVDTRLNP------------SVFV
IFQKDQIYPA-----YVIEYSETD-----------KPCVIS---

MADPEVCCFITKVLCAHGGRMALDALLEEIRLPEGQLLEVLEEAGPDRFVLLETGGREGI
TRSVVATTG-ARVCRRKFCQR-PCED-LHLCKLNLLGRCNYTQT-DRNLCKYSHNVLSEE
NFKVLKNHELSGLNQKELAVLLLQSDPFFMPEIC--KNYKGEGRKVTCNKYPQCERLHI-
CEHFTRGNCGYPNCLRSHNLMDRRVLAIMRE-HGLSSSVVQNIQDICNSKHS--PKKHSG
HRGPPAYRRD-----PAYRGRSKSRDRSFHGSMEFLPSASASTQKSCAAA-ADQIGHR-L
PQEDVPV---EDLAHKFVHLGSQDG-PQPSPVPPQMDH-VRGRSQVGRSQRF-SENGSPK
DLFYGNQGSVYLPSDS--KPASSQKGPASSLNGKGTGRESLFSQSQAASGSPPGSPQTPD
AMTAWKNTGLLSS-DGVNAGGRSGKQNVQ-YGPLFNNNVDGTAAD-TTSTRSFSYKTATS
GQR-----------EKSLPRSQDA-RTTHGN----------------VQTTG----KVAG
GDDPAVASVNGPCREKTVWANHSVHGTPDSSSQVADETFRVSKTG--AAGFDFTLPS--R
GDKNASCFGSQNLEGEVVPTPWETTVPTP---QVRTPSKVPSSTSSSSDKSAVYASHGQN
SAPVLVSPASEL-AR-----TPRYPPYFASDVESTSSSRMADCGSKEICLDHLCRGCQV-
----------ESCNKVHFHLPYRWQMWLGNTWMDFQPMETIEKAYCDPQIHTF-SIGDKD
IDFQKMT-CNFNPIRRISTPSSVI-VLTNFVFATRWIWYWKSQSDKWVEYGEEADSHQ-A
SS--IDSSYLESFFLGHPRGV-VAFHVGSQNYELSFA--GMIQTNVASRTQKRVVRRP-K
FMSY--KDVEQIKSG-FSY----------QLAPPRSDPLS--PALLPQWDFG--SDGYEL
S---DIPCRVL

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYIKIDTYFKASMKNFKVERIRKIKNTKLLSAFERKKMKM-NNRKEEIL
FYATDHVHLDSICRDNFDWLLHGAG-KPKYGKGIYFTKDAIHAHKNCQCDT------KNI
VMFVARVLV-GDFTQGEMGSISPPP------PPYNSYVDIRSNP------------SVFV
IFDKDQIYPE-----YVIEYTELD-----------KGCVIS---

MADPEVCCFITKILCAHRGRMAMDALLQEIKLSEAQLCEVLQVAGPDRFVVLETGGVAGV
TRSVVATTR-ARVCRRKYCRS-PCDN-LHLCKLNLLGRCNYSQS-DRNLCKYSHEVLSDD
NFRVLKIHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRQQICSQQPPCARLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLITLTPMFIIL---------FHFGFF
LLAPT-HRGN-----MAHRARSKSRDRFLQGSQEFLASASASAQRTCTPS-PDQIGHR-A
SLEDVHV---DNLTYKFGYLGNQAH-TRLPSGSSKATD-LGGTSQAGASRGF-SENGSLH
GILYGNPGDTYLASDS--TPAPNWKGPTSWTNDKGTGRESVFSPTLPAARSSLGCLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDMQ-PGPLFNNNADGVATD-ITSTRSLNYKSTNS
GQR-----------EISSPRNQDA-GPASRD----------------LQATG----RITD
GADPRVALVNGKYGGKTIWASTFVHDALTGSSKVADKTIDVGKMG--ATGFGLTMA---V
MGEKDI----QSLRSLVPATLGETAVPA----QVSTLPQSPA-APSSSNRAAAWGAQGQN
CTQAPVSSASEL-TR----RTTGCARYSLSDVTSTASSRVDDHGSKEICLDHLYKGCPL-
---------NGSCTKVHFHLPYRWQMLISR

PF02825 // ENSGT00760000119084_5_Domain_1 (751, 896)

TWTDFQFMEKIEEAYCDPQIHLS-------
------------------------------------------------------------
-S--IDSSYLEAFYQSCPRGV-VPFQAGSRNYELSFQ--GMVQTNVASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSL--WDVEQMKRG-PDH----------QPAQTSSAPLT--ATFLPQQDLC--FLSSKK
YKVSEINHQHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYVKVSEHFKASMKHFKIENIKKIQNPELLDCFTRKKLQM-K-VEENLL
FYATKRAYVESICANNFDWTLHETH-ATTYGKGFYFAKDAIYSHKNCPYDA------KNI
IMFVARVLV-GNFTEGNMTYT-SPP------PLFNSCVDTRLNP------------SVFV
IFQKDQIYPQ-----YVIEYTETD-----------KACVIS---

MADPEVCCFITKILCAHRGRMAMDALLQEIKLSEAQLCEVLQVAGPDRFVVLETGGVAGV
TRSVVATTR-ARVCRRKYCRS-PCDN-LHLCKLNLLGRCNYSQS-DRNLCKYSHEVLSED
NFRVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRQQICSQQPPCARLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLSPDVVQNIQDICNSKHM--QKNAMG
PRAPA-HRGN-----MAHRARSKSRDRFLHGSQEFLASASASAQRTCTPS-PDRIGHR-A
SLEDVPV---DNLTYKFSYLGSQAH-TRLPSGSSKATD-LGGASQAGASRGF-SENGSLH
GILYGNPGDTYLASDS--TPAPSWKGPTSWMNDKGTGRESVFSPTLPATHSSLGCLQTPE
TVTTRKGAGLLSS-DYRNIDGKSGTQDMQ-PGPLFNNNADGVAKD-ITSTRSLNYKSTNS
GQR-----------EISSPRNQDA-GPASRG----------------LQTTG----RIAD
GADPRVALYLCPRC--AGWKNG-------------------------CHWFWLNNGS--H
GGKRYVTFESQSLRSLVPATLGETAVPA----QVSTLPQSPA-ALSSSNRAAVWGAQGQN
CTQAPVSSASEL-TR----RTTGSAQYSLSDVTSTASSRVDDHGSKEICLDHLYKGCPL-
---------NGSCTKVHFHLPYRWQMLISRTWTDFQFMEQIEEAYCDPQIHLC-SVGSYT
INFREMT-CGSNRIQRLSTPSSVT-KPANLVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDNQK-S
SS--IDSSYLEAFYQSCPRGV-VPFQAGSRNYELSFQ--GMIQTNVASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 971)

RRP-K
FVSL--WEMKQMKRG-TDH----------QPAQASSAPLT--ATFLPQQDLC--FLSSEK
YKVSEINHLH

PF00644 // ENSGT00760000119084_5_Domain_2 (971, 1112)

SEYVKVSEHFKASMKHFKIEKIKKIENPELLDCFKRKKLQM-N-VEENLL
FYATKRAYVESICANNFDWTIHETH-VAAYGKGGYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFTEGNMTYT-SPP------PLFNSCVDNRLNP------------SVFV
IFQKDQIYPQ-----YVIEYTETD-----------KACVIS---

MADPEVCCFITKILCAHGGRMALDALLEKIALTEAQLREVLEAAGPDRFVLLETGDRARV
TGFVVATTR-ARVCRRKYCQR-PCED-LHLCKLNLLGRCRYSQS-ERNLCKYSHEVLSEE
NFKVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KNYKGEGRKVICDQHPSCERLHI-
CEHFTRGICGYANCLRSHNLMDRRVLAIMRE-HGLSPSVVQNIQDICNSKHG--RKKHPR
GKAPCSHRRD-----VAYRGRSKSRERSFQGGPEFLPPASASTQKSSTPS-SDQIGHR-P
PLDDMPV---GELAHKFMHLGSQDC-PQPSPVSPKVDN-LGGTGHMERSQRF-SENGGPE
DLFFGNQGSTSLPSDP--MPASNRRGPASWLNDKGTGRGSLFAQSQAASGSPLGSPQTPE
TTTTRKSAGMLST-DGTNAEGRSGNQNVQ-YFSLFDNNVDGAATD-GASASCLNYKTTTS
GQR-----------EKSLPRNQDT-GTTHGG----------------LQTTG----KITD
GADPAAASVNSNHSEKTVWPGKSIHSTPNGSSQVADETTDVNKTG--AAGFGFTLTC--R
GDKNVLYFGSPGLGAQVLPTPQETPAPT----QVSTLPKVPPSTSFSSNRAAAYATHGPN
SAQISAGPAGDL-V------GPSCDLYSASDVENTSSSRMDDCGPQEICLDHLCKGCHL-
----------ASCNKVHFHLPYRWQILLANTWMDLQPMENIEKAYCDPQIHSF-SIGNKN
INFQMMV-CNCNPIRRISTPSSVT-VLTNFVFAT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWRNKSDRWVQYGEKVDKQQ-A
AN--VDSSYLESFFLCSPRGI-VPFQAGSQSYELSFM--GMIQTNVASKTQKNVV

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FMSY--EDVEQIKRG-FKH----------QPVQTLSEPLT--STLFPQQEFG--LNGYEL
L---EINQQTL

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYDTISERFKASMKNFKIENIKKIKNTKLLNAFERKKMKM-NNKRENIL
FCATSRAHVESICANNFDWILHGTD-ENKYGRGNYFRKDAIYSHKNCRYDT------KNI
VMFVARVLV-GDFTQGAVGSISPPP------PPYDSYVDARLNP------------SVFV
IFEKDQIYPE-----YVIEYTELD-----------KACVIS---

MADPEVCCFITKILCAHGGRMALDALLEEIALSEPQLCEVLQVAGPDRFVVLETSGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KNYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSSHR-A
SLEDTPV---DDLTHKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGASRRF-FENGSQE
DLLHGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTVFPPTLPAALSSLGSLQTPE
AVTTRKGAGLLSS-DYRNINGKSGTQDVQ-PGPLFNNNADGVATD-TTSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPASRD----------------VQATG----RITD
DAGPRVALVND-------------------------------------------------
------------------------------------------------------------
---------------------------SLSDVTSTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGSCSKVHFHLPYRWQMFIGETWTDFKPMEMIEEAYSDPRIHVC-SVGSYT
INFREMS-CDFIPIRRLSTPSSVT-KPANSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 877)

KWIWYWKNESGTWIQYGEEKDNQK-S
SK--IDSLYLESLCQS----F-VQFQAGSRNYELSFQ--GEFLVLAVWCVIEICLQCTRV
SGAR--WVCIAMARV-KGQ----------DLGKRGLQAM-----------------ASET
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

MADPEVCCFITKILCAHGGRMALDALLEEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHHRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSGHR-A
SLEDTPV---DDLTHKFSNLGSQDR-ARPPLGSSKATD-LGGTSQAGASRRF-LENGSQE
DPLRGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTVFPPTLPATLSSLGSLQTPE
AVTTRKGAGLLSS-DYRNVNGKSGTQDVQ-PGPLFNNNADGVATD-ITSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPASRD----------------VQATG----RITD
DAGPRVALVNGKYKGKKFGASTFVHDTPNGSSQVADKTTDVEKTG--ATGFGLTMAV--M
GEKDKLRSGSHSLRSLVPTTPGESTAPA----QVRTLPQSPA-ALSSSNRAAVWRAQGQN
CTQVPVSPASEL-TR----KTTGSAQYSLSDVTRTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGSCSKVHFHLPYRWQMLIGKTWTDFNHMEMIEEAYSDPRIHIC-SVGSYT
INFREMSCCDFIPVRRLSTPSSVT-NPANSVFTTTWIWYWKNESGTWIQYGEE-------
----------------------------------------MIQTNKVSKTQKDVIRRP-K
FVSP--WDVQQMKRG-PDR----------QPAQTSSVSLT--ATFLPQEDLC--FLSSKK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1160)

EYVKVSEHFKASMKNFKIEKIKKIENPELLDKFTRKKSQM-K-EEGSLL
FYATSRAYVESICANNFDWTLHETH-ETKYGKGSYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYT-SPP------QRYNSCVDTGLNP------------SVFV
IFQKDQIYPQ-----YVIEYTDAD-----------KACVIS---

MADPGVCCFITKILCAHGGRMTLEELLAEIALPEAQLRELLEAAGPDRFVQLEIVGQTGV
TRSVVATTR-ARVCRRKYCER-PCDS-LHLCKLNLLGRCHYSHS-QRNLCKYSHEVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICGQPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMKE-HGLSSDVVQNIQDICNSKHS--RRNPPA
MRAPQPHRRG-----RA-RGRSKSRDRFFQNSLEFLPT-VSP-AESGPPS-PDATSCK-G
SLEDVSA----DVTQKFKYLGTQDC-AQLSSVSPKAAG------LRGAGLKF-SENGDPG
GLFSRSCSDSSSNL--------------------------------AASGFHLDVTQTLE
AMAKKTD--KLSG-YHMDVKNRSKAHDKQ-HVPFFDSCAGGAKME-GTASGILGNRATAN
GLG-----------EI-LPSNHRKSAGNLLD----------------LQITSRVADSIAD
-SGQDMAFLGGKYGGNTVWASKSTHSDPNGSSQIMNKTPDVSKSS--ATGFGVKAAV--T
GRKEAMSFGGQSLRSQVLAMPEEITAAVP---A-SRLPQTPP-PS-SSHRVAASEILGKN
STHATVSPVCKP-SR----RTS-DSEYPLFSIASSTSPRMDDHGPKEICQDHLYKGCHQ-
----------SNCNKSHFHLPYRWQLFIDNSWVDFQDMEDIERAYCDPQTESV-MIGEYQ
INFQKMT-CDYFPIRRLSTPSFDA-QSVNSVFSTT

PF02825 // ENSGT00760000119084_5_Domain_1 (816, 896)

WLWYWKDEFNKYVQYGDENKSHL-S
SN--ISSSYLESFFQSCPRGV-LPFQAGSQNYELSFQ--GMIQTNIASKTQRRVV

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-V
FVAW--KDVERRRRG-ADR----------QPVMPAVEALT--LDSPPLRDTGTFPFPSNR
YELVELDSQDV

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYATISELFKASMKYFKIVSIKRIWNQDLWETFERKKLMM-KNDNEMLL
FHATCRVHVDYICRNNFDWIINDSR-ETKYGKGNYFAKEAMYSHKNCSYEA------KNI
VMLVARVLA-GNSIEGNMRYS-SAP------ALYDSCVDSRLNP------------SVFV
IFQKEQIYPA-----YVIEYTELE---------KEKACIIS---

MADPGVCCFITKILCAHGGRMTLEELLAEIALPEAQLRELLEAAGPDRFVQLEIVGQTGV
TRSVVATTR-ARVCRRKYCER-PCDS-LHLCKLNLLGRCHYSHS-QRNLCKYSHEVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICGQPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMKE-HGLSSDVVQNIQDICNSKHS--RRNPPA
MRAPQPHRRG-----RA-RGRSKSRDRFFQNSLEFLPT-VSP-AESGPPS-PDATSCK-G
SLEDVSA----DVTQKFKYLGTQDC-AQLSSVSPKAAG------LRGAGLKF-SENGDPG
GLFSRSCSDSSSNL--------------------------------AASGFHLDVTQTLE
AMAKKTD--KLSG-YHMDVKNRSKAHDKQ-HVPFFDSCAGGAKME-GTASGILGNRATAN
GLG-----------EI-LPSNHRKSAGNLLD----------------LQITSRVADSIAD
-SGQDMAFLGGKYGGNTVWASKSTHSDPNGSSQIMNKTPDVSKSS--ATGFGVKAAV--T
GRKEAMSFGGQSLRSQVLAMPEEITAAVP---A-SRLPQTPP-PS-SSHRVAASEILGKN
STHATVSPVCKP-SR----RTS-DSEYPLFSIASSTSPRMDDHGPKEICQDHLYKGCHQ-
----------SNCNKSHFHLPYRWQLFIDNSWVDFQDMEDIERAYCDPQTESV-MIGEYQ
INFQKMT-CDYFPIRRLSTPSFDA-QSVNSVFST

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

TWLWYWKDEFNKYVQYGDENKSHL-S
SN--ISSSYLESFFQSCPRGV-LPFQAGSQNYELSFQ--GMIQTNIASKTQRRVV

ENSGT00760000119084_5_Linker_1_2 (896, 961)

RRP-V
FVAW--KDVERRRRG-ADR----------QPVMPAVEALT--LDSPPLRDTGTFPFPSNR

PF00644 // ENSGT00760000119084_5_Domain_2 (961, 1161)

YELVELDSQDVEYATISELFKASMKYFKIVSIKRIWNQDLWETFERKKLMM-KNDNEMLL
FHATCRVHVDYICRNNFDWIINDSR-ETKYGKGNYFAKEAMYSHKNCSYEA------KNI
VMLVARVLA-GNSIEGNMRYS-SAP------ALYDSCVDSRLNP------------SVFV
IFQKEQIYPA-----YVIEYTELE---------KEKACIIS---

MADPEVCCFITKILCAHGGRMALDQLLKKILLSETQLCEVLEVAGPDRFVMLETGGXXXX
XXXXXXXXXXXXXXXXXXXXX---XX-XXXXXXXXXXXXXXXXXXXXNLCKYSHDILSEE
NFRILKSHELSGLNQEELGVLLIQSDPFFMPEXXXXXXXXXXXXXXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXXX-XXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXPSSNRRG-----VAYRGRSKSRDRSFLDSQEFLPSASASTPRSCTSS-PDNIDSG-S
PLDD--V---KDLTHKFMYLGSQDS-SQPS-VSSRPTD-LVGTGQVGASHSC-SENDSRE
GLLFGNR---FSAFNS--TSAANRKGPTSWLNDQSTEKESLFSENQAASFSGLISVQTPE
TVTTTKNPGRPSSDLSSNIEGRSGNQDVQ-LFSFLNNIIDEMATG-TTSMRSLNYKTTSN
RQR-----------EKSLSRNQDT-GTTHGN----------------PQITG----KIAE
GDQG-VASVN--------------------------------------------------
------------------------------------------------------------
--------------------------DSLSDINSTAFSKIDDHGS-NICLDHLYKGCLL-
---------TNSCSKVHFHLPYRWQMLTANTWMDLKLMEMIEEAYCDPNNCII-SIRHHN
INFQEMT-CDANPMRRISTPSSMA-KLTDSVFTTKWIWYWKDDSNNWIQYGEDKGNQK-T
SN--INSSYLESWFLSCRRGI-VSFQAGSQTYELSFQ--GMIQTNIASKTQKDVIRRP-K
FVSS--EDVEQIKKG-ADS----------QLAQTPSDALT--SKFHPQWDHH--CLPIN

PF00644 // ENSGT00760000119084_5_Domain_2 (960, 1162)

G
YELSEINDQTTEYAAISARFKASMKNFKIEKIKKIQNPELLQTFEKKKSKM-KLSCEKLL
FFATYRAHLEYICANNFDWTYHGPF-ETKYGKGNYFTKDAICSHKSCGHEA------KNI
AMFVARVLV-GDFIEGNMTYI-RPP------SLYDSCVDVRSNP------------SIFV
IFQKDQIYPA-----YVIEYTEID-----------KPCVIS---

----------------------------KIALSEEQLCEVLEAAGPDRFVVQETEGR---
--WVVATTR-ARVCRRKFCQR-PCEN-LHLCKLNLLGRCNYSQS-QRNLCKYSHEVLSED
NFRVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRQQICSQQPPC

PF00642 // ENSGT00760000119084_5_Domain_0 (175, 200)

DRLHI-
CEHFTRGNCSYSNCLRSHNLLDRKVLAAMWE-HGLSVDVVRNIQDILNSKHARGRKHPPA
RRAPPSNRRD-----VGYRDRSKSRDRFFQGHQEFFPPADASCQRSCTSS-PDITSSR-P
PPDDVVV---EDLAHEFTHLGSQDS-SPPSPVSPKTTS-FAGTGQMEANHRF-SENSSRE
GLFYGNLGNTRPVSDS--MPTSNQKEPTSWVNGQGPGRE---------------------
--------------NCVDIKGESGNHEVP-HFSFFNKTVDGTATD-PSSTRSSSYKTTAS
RQR-----------EESLHTTQDN-GTSRGN----------------QQATG----KIAE
-DDPDMVFVSGHTYPNTYWSTKYVPNMLNDSVKATDKTTDGAKTG--AISSS--LRVAAK
DDKDVFASESQSQRTQGFLKPGEATAPA----QVSSPPTV---SPSSSDRATACGIGGHS
SAHISVTPAAGFTTR----RTQDSALYSSSNVTSITSSKIDD-GSEEICLDYLYKGCQP-
---------NKKCSKVHFHLPYRWQILLSNTWIDLQPMEKIEKAYCDPNNSIF-SVGSHN
ISFQEMS-CEFHPIRRLSTPSSCT-KSVTSVFATKWIWYWKDKSGDWIQYGEKKDNQQ-I
SN--ITSSYVESLFLSYPRGI-VQFKAGSEEYELSFP--GMIQTNTASKTQKDVARRP-Q
FVSS--RDVEELLKG-PGV----------SSVSVRLVSLVLFFS-SPNNRLAY-KTNDKN
HELSIISERLPEYTMISESFKASMKNFRIEKIRKIHNPELLDAFQRKKAKM-KNANEKIL
FYATNRSHMDSICANNFDWTLHGTH-DTKYGKGLCW------------------------
------------------------------------------------------------
--------------------------------------------

MTDPEVFCFITKILCAHGGRMTLEELLGEISLPEAQLYELLKAAGPDRFVLLETGDQAGI
TRSVVATTR-ARVCRRKYCQR-PCDS-LHLCKLNLLGRCHYAQS-QRNLCKYSHDVLSEQ
NFQVLKNHELSGLNQEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICGQPQPCERLHI-
CEHFTRGNCSYLNCLRSHNLMDRKVLAIMRE-HGLSSDVVQNIQDICNNKHT--RRNLPG
MRAPHPHRRG-----GAHRDRSKSRDRFHHNSQEFLST-VSP-LGSGPPS-PDVTGCK-D
SLEDVSA----DVTQKFKYLGTQDR-AQLSSVSPKAAG-VRGPGQMRASQEFFSEDGDPD
GLFSRDCSDSSSSRT-------------------------------SAAGFPLDAAQRNE
AGAMKMG--MPSG-HHVEVKGTN--EDID-RVPFLNSYIDGVTMEEATVSGILGKRATDN
GLE-----------EMILPSNHQKSVAKTQD----------------PQAAG----RITD
-SGQDTAFLHSKYGENPAWPGTSTHNGPNGFSQIMDETPNVSKSS--PTGFGIKSAV--T
GGKEAVYSGVQSLRSHVLAMPGETTTAVQ---GSNRLPPSPL-SSSTSHRVAASGSPGKN
SAHASMSPASEP-SRMM--MMSDPAEYSLDYIVNPVSPRMDDHGPKEICLDHLYRGCQQ-
----------GNCNKNHFHLPYRWQLFILPTWMDFQDMEYIERAYCDPRIEII-VIEKHR
INFKKMT-CDSYPIRRLSTPSFVE-NTLSSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWLWYWRNELNEYTQYGEESPGHT-S
SE--INSAYLESFFHSCPRGV-LQFHAGSQNYELSFQ--GMIQTNVASKTQRHVV

ENSGT00760000119084_5_Linker_1_2 (896, 962)

RRP-V
FVSP--KDVEQKRRG-PDH----------QPVMPQADALT--LYSPPQRNAST--VSPDE
Y

PF00644 // ENSGT00760000119084_5_Domain_2 (962, 1112)

EFIELNSQDEEYAKISERFKASMKQFKIVTIKRIWNQKLWDTFESKKQKM-KNKTEMFL
FHAAGRIHMDYICKNNFEWILHGNR-ETRYGKGNYFTKEAIYSHRS-SYDS------RGT
VMFVARVLV-GSVIEGNMTLS-SPP------ALYDSCVDTRLNP------------SVFV
IFRKEQIYPE-----YVIEYVESE---------KEKGCIIS---

MADPGVCCFITKILCAHGGRMALEELLHEMQLSEEQLCEVLKEAGPDRFVVLEMGGKEGV
TRSVVATTR-ARVCRRKYCNK-PCGN-LHLCKLNLLGRCHYSQS-ERNLCKYSHEVLSED
NFRVLTNHGLSGLNQEELAVLLLQSDPFFMPEIC--KNYKGEGGRQICNQQPPCERLHI-
CEHFTRGNCGYANCFRSHNLMDRRVLAVMRE-HGLSSSVVQNIQDICNSRHR--QKKPSA
WKAPPPHRRD-----LAFRGRSKSRDR---GSEEFLPAASASAQRSCSPS-PEPPGHRGS
VASDGPV---EDLARQFSHLGSQEC-PPPASNPSAAVV-LGGTPQGGGNQRL-AENGSAK
DLFYGNHSHAPLTFDL--KPAFNWKGPASWQNDQDTGKKSWLPSSPVFSSS-PGSPQTPE
---TRKTTAVLSS-DHVNAERRSGNQDGQ-HFPLFADKADGMAVD-TTSTRRANYQTPSS
RQR-----------EKSLPRNPDT-GTPRSH----------------LPTAG----QMT-
-GDGAAAFVN--------------------------------------------------
------------------------------------------------------------
--------------------------DSVPNVASTISSTMNEHSSNEICLDHLYKSCQL-
---------TKSCNKVHFHLPYRWQMLLANSWVDLPFMEDIEKAFCDPKNCSV-SVRTYN
INFQKMI-CDFNPVRRISTPSSVT-QPPSSLLTTKWIWYWRNGT-KWVPYGEKKDNEQ-I
SS--IDSSYLESLFLSCPRGI-VPFQAGSRNYELSFQ-EGMIQTNIASKTQKDVIRRP-T
FVSY--WDVEQVKRR-QDP----------QQGQTSSEPFI--NIYLPQPDTS--VPGSNG
FELLE

PF00644 // ENSGT00760000119084_5_Domain_2 (966, 1161)

IPSNTPEYAKVSDHFKASMRNFKIEKIKKVQNAQLLEAFKSKKNEM-K-REEQIL
FCATERSNVASICKNNFDWLLHGSH-DTKYGKGNYFTKDAFSSHKNCPFDS------RNI
VMFVARVLV-GNFIEGHTSYR-SPP------LQYDSCVDTRLNP------------SVFV
IFQKDQIYPE-----YVIEYTEPE-----RS---EKPCLIS---

MADPEVCCFITKILCAHGGRMALDALLEEIALSEPQLREVLQVAGPDRFVVLETSGEAGI
TRSVVATTR-ARVCRRKYCQR-PCEN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NFRVLKNHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CEHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFFQGSQEFLASASASAERSCTPS-PDPSSHR-A
SLEDTPV---DDLTHKFTYLGSQDR-ARPPSGSSKATD-LRGTSQAGASRRF-LENGSQE
DLLHGNPGNTYLASNS--TPAPKWKSPTSWTNDQGARRKTGFPPTLPAALSSLGSLQTPE
AV-TRKGAGLLSS-DYRNVNGKSGTQDVQ-PGPLFNNNADGVATD-TTSTRSLNYKSTSS
SQR-----------EISTPRTQDA-GPASRD----------------VQATG----RITD
DAGPRVALVNGKYKGKKLGASAFVHDTPNGSSQVADKTTDVEKTG--ATGFGFTMTV--M
VEKDKLRSGSQSLRNLVPTTPGESTASA----QVSTLPQSPA-ALSSSNRAAVWRTQGQN
CTQVPVSPASEL-TR----KTTGSAQYSLSDVTSTTSSRVDDHGSKEICLDHLYKGCPF-
---------NGEYITVCIYI--------------------------------C-IYNIYM
DNYKI------------------------TVFQNK-----KFIERNFIFLQNNKDNQK-S
SN--I

PF02825 // ENSGT00760000119084_5_Domain_1 (846, 896)

DSLYLESLYQSYPRGV-VQFQAGSRNYELSFQ--GMIQTNKASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-K
FVSQ--WDVQQMKRG-PDR----------QPAQTSSVSLT--ATFLPQEDLC--FLSSNK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1160)

EYVKVSEHFKASMKNFKIEKIKKIENLELLDKFIRKKSQL-K-EEESLL
FYATSRAYVESICANNFDWALHETH-ETKYGKGYYFAKDAIYSHKNCPYDA------KNI
VMFVARVLV-GNFIEGNVSYM-SPP------QQYNSCVDTRLNP------------SVFV
IFEKDQIYPQ-----YVIEYTDAD-----------KPCVIS---

------------------------------------------------------------
-------------------------------------RLNYCYI-RTNYCKYSHDIHSEK
NIKILKKHDISVLSKNELAVLLLQSDPFFLPDIC--KYYKGENKKDSCT-NTECMKLHI-
CEHFVEGKCGFVNCIRSHDLMGTKVLELLKE-EGLTIPVIRNIQDICDQKHIRSKKRISR
RRDKSTQRNV--------GYRSQSRNRYFFGTQELPTSPSASVETAHIPE-PDKTGSA--
PLPSSEGKVNEKGVPENNSSLRQDS-VQSVSASTKTVS-IQQASQLGTNLSR------RE
G-QYGTQDGTQHAVSI-SAPAPAA----PAGDSQLFRRVKVLFGNDDD------SCSDPA
PQTTSKSESMSSS-NATSAGNDCEGQKAH-PSLAPNKIVDTWDKN---------------
-DR-----------EETLCMPQKD-QASPRDKAAAAYVQPKTPSASDVPQSG-----IKK
DGLAQSSLPTGKHKFTNVFIYRHINNVFYGSKLLPRQSYCVAKEG--ITQLDLCMYLYAL
KNLDSIGS----PKGSVSASPSQTLATLGIN---KSRAVSPSKSTNAEGKKLSTAEIASQ
CESVPSSTLDSFISQ---THSNQDVPVSQARILNTIPSGMENNNSNKICLDYLNGDCKL-
---------KECCKDIHFYLPYRWQVCISNVWEDLKDMEEIEKAYCDPTIYKC-PLRSHS
IDFQEMLLFGFYPVRRLSTPSTIQ--NSTCALSTKWHWYWKNELDQWIEYGKEKKGYFKQ
EDSEFTSEDLELFFLVSPETV----SLSHHKYKLNFN--DMTQTNIVSGITREVRRRP-Q
FVSSVTVYWNQKRKKLKDE----------QKEKPQSVYLC--QSYYRKQDIS--FISQSK
Y

PF00644 // ENSGT00760000119084_5_Domain_2 (962, 1160)

KLFEIKRPSFEYSEIEYSFKSTMKNFEIQKIMRIQNPSLWNNFQRKQKKMLNGGNKKLL
FHAADPNSIDSICSNNFSIWSPQSFQQTIYGTGIYFTKDAISSHYKIKNNH------KIK
IMFIAQVLV-GMSVQGKVGYTSQNL------PIYDSYVDNMTNP------------SIFV
INDKENIYPH-----YIIEYTDID-----------KSCNIS---

MADPEVCSFITK-LCAHGGRMALDALLDEIALSEAQLLEVLEAAGPSRFVVLETGGRAGV
TRFVVATTA-ARVCRRKFCPT-DCGN-LHLCKLNLLGRCHYTHS-DRHLCKYSHDVLSEA
NFIVLKRHQISGLNKEELAVLLVQSDPFFMPEIC--KSYKGEGRKQICGHQPMCERLHI-
CEHFTRGNCGFTNCLRSHNLMDRKVLEMMRE-HGLSREVVQNIQDICNNKHN--RRRP-G
LRG-PSRNRD-----PAARGRSKSRDRFFQASQEFLPSAPASTETPSTPS-ADQIGRR-S
PRDDVPV---EDLTCKFKHLGSQDG-PQPSSASPKAAN-LGGSRPVGGTQRF-SENGSLE
DLFYDSTASSHLTSDL--TPTFNQKVPPSWPNDQGTSRENLFSPSQAASYSPLGSLQTPD
TVTTRKGVGMLSP-GHMNIEGRSGNPEVQ-HFPLSNNNLDGMATD-TMSTRSLNYKTATS
RQR-----------ENSLPRNQEI-RTTHPT----------------LDPII--------
-------VDDGKHREQVF-----FHNTTNGSTKVIYEST-----D--ATDFDLTSAVRAR
VDKDVLGSASPYLRPQILRMLGETTAHT----VVSTVPKGPPLTPSSNNRATAAAAHDRN
SAQMPVTSASEL-AR----RTPGCALNSVSDVTN----TMDDPGSKEICLDHLNKSCQS-
---------IKGCSKVHFHLPYRWQVMNANTWVDLQPMESIEKAYCDPQICII-PFGNLK
INFQKMT-CGSDPIRRLSTPSSVT-RPDNSVFTTKWIWYWKSGSHRWIPYGEKGDSRQ-I
SS--VDSSYLESVFLCTPRGI-VPFQAGSEDFELSFQ--GMMQTNIVSKTQKDVARRP-T
FVSA--RDVAQMKSG-PDH----------QPAQTLPEPGI--LVFLPEQKLP--SPPLN

PF00644 // ENSGT00760000119084_5_Domain_2 (960, 1162)

G
YELSEINSYGSEYAKVTAYFRVTMRHVKIEKIKKLKNPQLLDTFQRRKMEM-K-VTEKYL
FCATHRAHVDSICANNFDWTLHGTS-EGTYGKGNYFTKDAIIAHKNFQSDP------KNI
VMFFARVLV-GDVIEGKRSYE-SPP------PPYDSCVDSRLNP------------SIFV
IFQKNQIYPE-----YVIEYTEAD-----------KACVVS---

MADPDVCCFITKILCAHGGRMSLDELLREIALPEAQLLELLEQAGPDRFVVLETGSRAGV
TRSVVATTR-ARVCRRKYCQR-PCDN-LHLCKLNLLGRCNYSQS-ERNLCKYSHEVLSEE
NRNILKLHELSGLNQEELAVLLLQSDPFFMPEIC--KSYKGEGRKQICSQQPQCDRLHI-
CDHFTRGNCSYPNCLRSHNLMDRKVLATMRE-HGLSPDVVQNIQDICNSKHA--RRNHPG
ARAPGAHRRG-----GAYRSRSKSRERFFQESQEFLSSASASAQRSSTPS-PDQIGCR-A
PEDDLSV---DDLTQEFTYLGAQDR-TQPSLASAKATS-LGGTG-----QKF-PENVNPE
GFFHGNHSNTYFLSDS--TPASNQKDPTSWLSDQGTRKESMFSPLLTGPHSPLGSAPTPA
AVTTRESTSLLYS-DLSDLNSTSRIQDIQ-HTLFNNNNADGEAIG-LIPPRSFNYKGTIS
GQR-----------ETSLPRNQDA-GPTPQD----------------LQTTD----KITE
SDYAGVAFVNRSGA----------------------------------------------
------------------------------------------------------------
------------------------------DVVCTTFSRMEDPDSKEICLDHLYKGCQL-
---------KSNCNKDHFHLPYRWQMLYEGLWRDLSTMEEIEEAYCNPQKIYFVTIGDYT
INFQKMT-CGSNLVRRISTPSSTT-NSANSFFTTRWIWYWKSESGRWIQYGKDQNNQE-C
ST--IDSSYLETIYQSCPQGI-ITFQVGSQKYELSFQ--GMIQTNIESKTQKDVIRRP-T
FVSL--WDMERIRRG-PDY----------QPVQASSASVT--ENFLPLQDLS--AFPSRG
YKLLE

PF00644 // ENSGT00760000119084_5_Domain_2 (966, 1160)

VNNQYLENARVSERFKASMKNFKIEKIKIIQNLELLNNFKRKKMQM-TNKTEKLL
FYATRRAYVESICANNFNLILHETH-ESKYGKGYYFAEDAIYSHKNCPYDA------KNI
IMFIARVLV-GSFIEGHMTYT-SPP------PGYDSCVDTRGSP------------SVFV
IFDKDQIYPE-----YVIEYTEVD-----------KACVIS---

MADPEVCCFITKILCAHGGRLALDALLDKIALSKAQLCEVLEAAGPDRFVVLETDA----
SKWVVATTR-ARVCRRKFCQR-PCDN-LHLCKLNLLGRCYYSQA-QRXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIC--KSYKGEGRQQTCNQQPTC

PF00642 // ENSGT00760000119084_5_Domain_0 (175, 200)

DKLHI-
CEHFTRGNCSYSNCLRSHNLLDRKVLATMRE-HGLDLNVVRNIQDICNNKHARGRRNPPG
RRVPPWNRRD-----VGYRGRSKSRDRGFQACPDFFPPTSASSHQRSRTSSPSISGSR-P
SLNDVVV---EDLTHGFMGLGSRDS-SPPSPGSPKATS-FAAKGQMGANHRF-SENNNQE
GLLYRNPGNTHPVSDS--VSASNQKKLAFWVNGQGTTGESLFSHSPPATFPP--------
-----KSASMLSL-DCXXXXX---------XXXX-XXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX----------------XXXXX----XXXX
XXX---------------------------------------------------------
------------------------------------------------------------
---------------------XXXXXXSLSNVTSTISSSI-DDGSEEICIDYLHKACQP-
---------NKKCGKVHFHLPYRWQILLANTWTDLHPMEKIEEAFCDPNNSIV-SLGSRN
ISFRQMI-CDFSPVRRLSTPSSRM-ESVTSVFATKWIWYWRDKSGSWIPYGEKXXXXX-X
XX--XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX--XMIQTNTASKTQKEVARRP-Q
FVFY--QDMEELLKR-PGXXXXXXXX----------XXXX---XXXXXXXXXX-XXXXXX
XX

PF00644 // ENSGT00760000119084_5_Domain_2 (963, 1162)

LSIISDQLPEYATISERFKASMKNFRIEKIKKIHNPELLNAFERKKLKM-KDANEKLL
FCATHRRHVDFICANNFEWILHGTH-ETKYGKGNYFAKEAIYAHKNCRCDE------KNI
VMFVARVLV-GDFTEGNMLYT-RPP------PRYDSCVDTKLDP------------SVFI
IFDRDQIYPK-----YVIEYSEID-----------KACVIS---

------------------------------------------------------------
-----------------------------------------------KLCKYSHDVLSEH
NSRILKTHELSGLNQEELAVLLKQSDPFFLPEXXXXXXXXXXX--XXXXXXXXXXXXXX-
XXXXXXXXXRLPNCLRSHNLLERRVLAVMEE-HGLSTDTVQNIQDICNSKHA--PQAPPG
-RVHSSHRRD-----PSSKERSKSRDQLSQGKQEFLSTLLTPLDRSCTPS-PDKWTFW--
--KDEPV---ERLTQKLGCLGSQGS--QPASVPSKTPG---G------------------
--------------------------PVTWLQDLSTREL--LAP-EPATRSPPGSPLRD-
---------LFAK-DFL-SIGRAGKQSWP--LPPFSNDGRVGAPA-SPPACTPLFRA---
-PK-----------EAPSPRSPG------------------------SPAPG-----SSP
DNGQGVAFVNXXXXXXXXXXX---------------------------------------
------------------------------------------------------------
---------------------------------XX---XXXXXXXXXXXXXXXXX-----
------XXXXXXCSQVHFHLPYQWQIYIDGAWTDLQPMETIEKAYCDPQNRFI-SVGNRI
INFQKMI-CNSHRIRRLSTPSSVI-TGTNSAFTTKWLWYWKNESDRWVEYGEXXXXXXXX
XX------XXXXXXXXXXXXX-XXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXX-X
XXXX-XXXXX----------XXXXXXXXHQPTQTRSESLTT--PCSSPEN--NGFLPSTG
YEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNYFTKDAISSQKICRGDP------K-N
VMFIARVLV-GNCIEGNKFYS-SPP------PM

PF00644 // ENSGT00760000119084_5_Domain_3 (1114, 1162)

YDSCVDTRLNP------------SIFV
IYEKDQIYPE-----YVIEYSEMD-----------KACVIS---

MADPTVCCFITKILCAHGGRLSLDELLRKIELSEVQLLEVLKEAGPDRFLVLETGDRAGV
TRSVVATTR-ARVCRRKFCDR-PCDN-LHLCKLNLLGRCHYSQS-ERNVCKYSHEVLSED
NFRVLKNHELSGLNQEQLAVLLVQNDPFFMPEIC--KSYKGEGRKQICNQQPPCERLHI-
CEHFTQGNCSYPNCLRSHNLMDRKVLAIMRD-HGLSPDVVQNIQDICNSKHM--RKNPPG
SKTP-AHRRG-----GAGRGRSKSRDRVSQDSKEF-PFTS--AHKLGTPS-PDGTSSR-A
ALEDRAI---DDLTRKLTFLENTAL-AQLSSVSSKASG-LGGPGQVGASPRF-SENGLPE
DLFYSNKSN--PASNS--TSASNRKSSPSWLNVQGTGKESALFPSQAVPGSPLDSTQTSK
AISSRMPMGVLSS-DHVNIKGKSGTPDTR-QVPLFNNTHDGVAMN-------MNFGMIPN
GQR-----------EIALPSYHQDSRATPLD-----------------HQIG----SIIS
-DDPGVAFPND-------------------------------------------------
------------------------------------------------------------
---------------------------SVSDVASTT-SKTGNHGTKDICVDYLHNCCQL-
---------NSSCSKIHFHLPYQWQVL-THTWVDLPNMEKIEKAYCDPQNFMI-LIGNHT
VDFQKMT-YSVRPMRRLSTPSSGT-NQANSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 897)

KWIWYWNNESGKWIPYGEGSNNQP-G
SD--VDSSYLESFFQSCPRGV-VPFQAGVQNYELSFQ--GMIQTNIVSKTQKIVVR

ENSGT00760000119084_5_Linker_1_2 (897, 962)

RP-T
FVSS--LDVEQMRRR-ADPPRVRFSASS-QPVQTPPKAAA--STFAPQRNVS--SLPAKG
F

PF00644 // ENSGT00760000119084_5_Domain_2 (962, 1161)

KLLDLSHESLEYASIRDYFKESMKNFKIEKIKKIHNPELLNCFERRRLMM-TEKKERLL
FYAASRTQVDSICANNFVWTSHGTH-ENKYGKGNHFSKEAIYSHKNSLYDA------KNI
VMFVARVLA-GDFIEGNMMYV-NPP------PPYNSCVDTMLNP------------SVFV
IFQKDQIYPA-----YLIEYSEI---DKEKDKDKEKACVIS---

MADPEVCCFITKILCAHGGRMALDALLQKIALSERQLCEVLQVAGPDRFVVLETGGEAGI
TRSVVATTR-ARVCRRKYCQR-SCDN-LHLCKLNLLGRCNYSKS-ERNSCKYSHEVLSEE
NFEVLKQHELSGLNKEELAVLLLQSDPFFMPEIC--KSYKGEGRQQICNQQPPCSRLHI-
CDHFTRGNCRFPNCLRSHNLMDRKVLAIMRE-HGLNPDVVQNIQDICNSKHM--QKNPPG
PRAPSSHRRN-----MAYRARSKSRDRFLQGSQEFLGSASASAERSCTPS-PDQIGHR-A
SLEDAPV---DDLTRKFTYLGSQDR-ARPPSGSSKATD-LGGTSQAGASQRF-LENGSQE
DLLHGNPGSTYLASNS--TSAPNWKSLTSWTNDQGARRKTVFSPTLPAARYSLGSLQTPE
AVTTRRGTGLPSS-DYRMINGKSGSQDIQ-PGPLFNNNADGVATD-ITSTRSLNYKSTSS
GQR-----------EISSPRIQDA-GPASRD----------------VQATG----RIAD
DADPRVALVNGKYKEKTLWASTFVHDIPNGSSQVVDKTTDVEKTG--ATGFGLTMAV--K
AEKDMLCTGSQSLRNLVPTTPGESTAPA----QVSTLPQSPA-ALSSSDRAAVWGAQGQN
CTQVPVSSASEL-TR----KTTGSAQYSLSDVTSTTSSRVDDHDSKEICLDHLCKGCPL-
---------NGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEEGYCNPGIHFC-SVGSYT
INFRVMS-CDSFPIRRLSTPSSVT-KPANSVFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWKNESGTWIQYGEEKDKRE-N
SN--VDSSYLESLYQSCPRGV-VPFQAGSRNYELSFQ--GMIQTNIASKTQKDVI

ENSGT00760000119084_5_Linker_1_2 (896, 972)

RRP-T
FVPQ--WYVQQMKRG-PDH----------QPAKTSSVSLT--ATFRPQEDFC--FLSSKK
YKLSEIHHLHP

PF00644 // ENSGT00760000119084_5_Domain_2 (972, 1161)

EYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM-K-EEGKLL
FYATSRAYVESICANNFDSFLHETH-ENKYGKGIYFAKDAIYSHKNCPYDA------KNV
VMFVAQVLV-GKFIEGNITYT-SPP------PQFDSCVDTRSNP------------SVFV
IFQKDQVYPQ-----YVIEYTE-D-----------KACVIS---

MADPEVCCFITKILCAHGGRMSLDELLKKIALPEAQLCEVLEAAGPDRFVVLETGGKAGV
TRSVVATTR-ARVCRRKFCQR-SCEN-LHLCKLNLLDRCHYSQS-ERNLCKYSHDVLSEE
NFRILKNHELSGLNKEELAVLLLQSDPFFMPEIC--KNYKGEGRRQICNQQPPCERLHI-
CEHFTRGNCSYANCLRSHNLMDRKVLAIMRE-HGLSQAVVQNIQDICNNKHG--RKKAPG
LRAPSSHRRD-----APYRGRSKSRDRFFHGSLEILPSASASTERSCTPS-PDQISGK-A
PLDDVPV---KDLTHKFMHLGSQDC-LQPAFVSLKPSN-LGGTGQVGGNQRF-AENGSPE
RLFRGNHGSSYRTSDS--TPGSIWKGPTSQLINKAASAEILFPQNQAASCSPLGSPQIPK
IITTRKSTGMFSL-D---DEGRSGSQDVQ-RFPLFNNNVDGMATD-VTSTRSFNYKTTTS
RQR-----------EKSLPRNQDT-GATHSN----------------LQITG----KITD
SDISA-LFVNDKHGEKRFGAGKSYHNTPNGSSKVTDEATEVARTG--ATSFGLPSAV--R
GDKDMLCSGSQNLRTQVLPTPGKTTAPV----QVSTLAKGSPSTPSSSNRAAAYGTHGQN
SAQISVTPANEL-SR----RTPGSALNSISDVANTTSSRMDDHDSKEICLDNLYKGCQR-
----------KRCNNVHFHLPYRWQMSIANTWTDLQPMENIEKAYCDPKIIFI-SIGNHR
VNFQKMT-CDFNPIRRISTPSSVM-MPANCVFATKWIWYWRNESDKWVQYGEKTDNQE-S
SS--IDSSYLESFFLCCPRGV-VPFQAGSRNYELSFQ--GMIQTNTASKTQKDVVRRP-A
FVSH--RDVERIKSG-LDH----------QLAQTRSESLT--STSLHQSDMG--FPPLNG
YE

PF00644 // ENSGT00760000119084_5_Domain_2 (963, 1118)

LFEIHNQYPEYAKISELFKASMKNFKIEKIKKIQNTKLWNTFERKKMKM-N-RNEEIL
FCATGRAYVESICANNFDWILHGAH-ETKYGQGNYFTKDAIISHKSCPGDP------KDI
VMFAARVLV-GDFIEGNMSYT-SPP------PPYHSCVDTSCNP------------SVFV
IFQKDQIYPE-----YVIEYTETD-----------KPCVIS---

MADPTVCCFITKILCAHGGRLSLEALLGKIELSEAQLLEVLKDAGPDRFLVLETGDRAGV
TRSVVATTR-ARVCRRKFCDR-PCEN-LHLCKLNLLGRCHYSDS-ERNLCKYSHDVLSED
NFRVLKHHELSGLNQEQLAVLLVQSDPFFLPEIC--KSYKGEGRKQICSQQVPCNRLHI-
CEHFTRGNCSYLNCLRSHNLLDRKVLAIMRE-HGLSQEVVQNIQDICNSKHM--RKNPPG
PKNA-GNRRG-----GVGRGRSKSRDRVPQDTKEFFPSTP--AHKSGTSS-PVGTSSR-A
SLGDKAV---NELTQKLAFLESRDLLAQPSSVSSKA------AGQLAASQRF-SENGLPD
GLFYNK---------------------------------SVFFPSQAAPGS-LDSAQTPK
ALTSRKPTGMLSS-DHVNIRGKSGTLDTQ-QVPLFNNNPDGVAAN-------MNFGMTPN
GQR-----------EIPLPSYQQNSKVTALD-----------------HQSG----RITS
-EDPGVAFLNGKYRGKTFGAGQFAYKGTK------------------S-----------H
GWGAAFYSGSQSARGQVPATAGETSVPA----QVHRLPQSPRPAS--GARA---------
-------------HT----CTFLCFIDCISDVASTT-SRTASHGLESICVDYLQNCCQL-
---------NSSCSKIHFHLPYRWQLL-THTWLDLSDMEKIEKAYCDPRNHMI-SVGNYT
IDFQKMT-CGSRPIRRISTPSSGT-NRTDSAFTT

PF02825 // ENSGT00760000119084_5_Domain_1 (815, 896)

KWIWYWQNELGKWVPYGEG----P-G
SD--VDSSYLESFFQSCPKGV-IPFQAGIRNYELSFQ--GMIQTNIISKTQKNVA

ENSGT00760000119084_5_Linker_1_2 (896, 970)

RRP-T
FVSS--LDVEQMRRR-PDH----------QPAQTLPKAVA--STFAPQSEGH--SLSSNG
YKLLDLSNE

PF00644 // ENSGT00760000119084_5_Domain_2 (970, 1161)

SVEYVNIRDRFKESMKNFKIEKIKKIHNLELLNLFERRRLMM-TEKKERLL
FYATSSAHVDSICANNFVWTSHGTQ-GSRYGRGNHFSREAIYSHRNCPDDA------RSI
VMFVVRVLA-GDFIEGNMLYA-SPP------PPYNSCVDTMVNP------------SVFV
IFQKDQIYPA-----YLIEYTEK---------EKEKACVIS---