Query Results 

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------RESISREYDVCMLYRNCVYTYRILPNEEDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDTGDEPEEETV---------DCVTSPPELPPRN-VPLSTG
---PYEAKEAPLSSESPRVPEVSKPTLSETLLQRLQSMDTSGLPDEYLKAIKDYLSTQLC
LDSEFVKTGASSLPHLKKLTMLLCKELYG----GASAAVKVVGEGRH-FVRTLDV-----
---------------------------------------------CL-------------
----RTVHLEVCAARG--------------------------------------------
-----VS-LALVKCPAKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMSFKTMA-HTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRLELPISXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX--------------
---------------------------XXXITFAPTYRF-RLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHNPVFATFEAGVTSQFVSKN-----GP
GT---ADSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKTQEGENEEGSEGELLV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEAKETQFPIYTPLT
HHGEMTGHFQGEIKLQTSQGKMREKLYDFVKTERDE-ASGPKCLKSFTSYDPMKLWESAN
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXX-X--XX--XXXXXXXX
X-------X-XXX-XXX--XXXXXX-----------------XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXPSDSGKSIAEPSLQEELPTTLIKREMFENPLYGSVSSFPKPAPRKE
QESPKMLRKETPPCPDPVTSSATIPLPKAQEADSSKGTSK----------LVPTTRLRSL
TCSTST--TDGAAAASGEKNPGKPKPAPCSQ-VP------VPAKRPVKPSRSELSQPSPA
AP----AQTRPPLPVKSPAVLHLQHSRGRDYRDNTELPHHAKHRPEEGP---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMKFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESIVSPPELPPRN-IPPSAG
---SCEAKEVPLSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESNFVKSQEGENEEGMRGSCPV
PFSL---QLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTVWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAISSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPAKSPAVLHLQHSKSRDYRDNSELPHHGKHRPEEGPPGPLSRTAMQV
RGATHGLVCMCARVHA--------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVHC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSKTGKDG
SFLVRASESISRAYALCVLYHNCVYTYRILPNDDEKFTVQASEGVPMRFFTSLEQLIDFY
KKENMGLVTHLQYPVQLEEEDAADDPEEETV--------IEFIMSPPELPPRN-IPLPAV
---LSETKETVLASDSSRGVESGKLSISETLLQRLQYLDTSGLPEDHLKAIQDYLNTHVT
ADFEFAKTGSSNLPQLKKLTMHLCKDLYS----EVTRTLPSLESMQKLFDQQLSPGIRPR
PQVPGEANPANMIVKLSQLTSLLSSLEDKAKALLVEGSESTHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVETGKLIIKKSKDGPEDKFFSH---KKILQ-LIKSQKFPNKLVIVVET
EKEKTLRKEYIFADSKILYKFLCLWKSFKGLHHLAPS--FLSSLLSFYR-----PPRTLR
SSAAHLLAVPRSRPSRRRPPGHVLPRSRNALPPH---LRQSDSLPLF--KSLLKTH--LL
REAFPDIAVHTLWNIRIVVLAKPEHE---NRISHICTDTVKTGIANTLGKKGGLYFLSFH
F-----------------------------------------PFSSFHRSIHHHHQGRVG
RHVSLP------------------------------------------------------
------------------------------------------------------------
--------------------------------TSRPVFAQIRSGKL--------------
------------------------------------------------------------
--GNLFPRLAP-------------------------------------------------
--GGI----RGTFS--------------------------------L-------------
-------------------------------------TPHFSGSNITEIINPNYMGLGPF
VTQMST--QVKQTLSPDQQPTLWSYDQPLKDSSLVPGWGDCPPTPPSQPPVSPKKFSPSS
SHRGPGPKTQE-QLPGDAGKNVAEHLSQEDLQ-----PEMFENPLYGSVSSFSKMAPRKE
QDSPKAPRKERQPGPEPPLG---FLLPKPPEAES-KSAGKQL----SAPFLTPMPRLRSH
TCSFA----DGKTAPGGEKAQGKPKPSTTTE-TP------VPAKRPVKPARSEMGQQSHQ
GL-----LNRPPLPAKSQAVLQLQHFKGRDYRESSELPHHGKHRPEEGP---VSRTPMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVHC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSKTGKDG
SFLVRASESISRAYALCVLFRNCVYTYRILTNEEEKFTVQASEGVPVRFFISLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPQEEEEAGDELEEETG-T-------EFFISPPELPPRN-LPLAPG
---SSEVKEVVPPADNSRVMEQSTLSLSETLLQRLQGLDTSGLPEEHLKAIQEYLSTQIA
LDSEFMKTGSNNLPNFKKLIMVLCKELYS----EVNKTLPSLESMQKLFDQQLSPGALPR
PQVCAEPNPANVIAKLSQLTNILSSLEDKVKTYVGEGPESTHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGPEDKFYSH---KKILQ-LIKSQKFHNKLIIVVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGTSPRPSPLE
S---VLSLS--FQSETPPDSAIF-----LFLGEQRQPLPYASWQAVGVIKHQVSSWMK--
SPTGALIAIHTLWNIRIVVLAKSEHE---NRISHICTNNVKTGIANALGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRLELPPSEAENIIQKIKQQQ-FPELLLHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERNNREKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGTTSDIMTSDHSPVFATFEVGVTSQFVSKN-----GP
GN---VDSQGQIEFLKCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGAEGELVV
KFLDDLPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRSEATESLVPIYTALT
HHGEMMGHFRGEIKLQTSQGKKRERLYDFVKTERDE-AAGQKSLKNLTNQDPTKHWECPP
RA--HF-----------------------------------SGANFTEITNPNYLGMGHF
GQQVPL--HGKPVLPTESQSTVWSYDQPPKDTPPISSWGESPPTPPSQPPLSPKKFSPCP
ASRAPNLRTQE-QLPSDLGKTVADPSTTEEQP--TTKPEMFENPLYGSVSSFPKPAPRKE
QESPKILRKERPVFVEPGAPSPSVIFLKAPEGESGKLASKAI----SAPF-LPVPRMRSF
TCSPSA---EGKAPMGGEKTQGKPKPLTPSE-TP------IPAKRPVKPARSEMSQPEPG
---TQGQINRPPLPAKSPAVLHLQHSKARDYRETSELPHHGKYWPEEGP---VSRTSMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MPAMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPE-DDKFTVQASEGVPMRFFTKLDQLIEFY
RKENMGLVTHLQFPVPLEEEDAIDEAEEDT--G-------ESVMSPPELPPRN-IPVSAG
---PCEAKDPPLPMENPRGPEVTRPSLAETLFQRLQSMDTSGLPEEHLKAIQDYVSNQLV
LDSDFVKTGSSNLPHLKKLTSLLCKELHG----EVIRTLPSLESLQRLFDQQLSPGLRTR
PQVPSEANPINMVAKLSQLTSLLSSIEDKVKALLHEGSEPPHRRSLIPPVTFEV--TTSR
RLWVP--------------------------HFS---RMLLQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFSDSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YSDLLAHDQLLLERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERMTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALHLETTETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGMKCLKNLTSHDPVRQWEPAG
RIP-AC-----------------------------------SVSSLNEIINPNYIGVGPF
GQPLHG--KS--TLSPDQQLTAWSYDQPPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGLCPRMQE-TRPADLGK--AEALLQEDLQ--MTKPEMFENPLYGSVTSFPKLAARKE
QESPKMLRKEPPPCPDPGISPPSILLPKTQEMEGVKGTGKQV----PVPVFGPTPRMRSF
TCSSSA---DGKVPSGDK-NQGKPKASASSQ-AP------VPAKRPIKPSRSEMSQQ---
-TTTPVPAPRPPLPVKSPAVLQLQHSRGRDYRDNTELPHHGKHRQEEGL---LGRTAMQV
C-----------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------SEGVPVKYFDNLEELIEFY
KKENMGLVWHLKYPVQREEEEAADEPEED-A---------DQVPTPPILPPRN-ILMALP
G---SETKDVSSLPENSRVADINKLSLSETLLQRLQYQDTSSVSDEHLKLIQDYLRVHII
SDLEMVQTGSSNLPQLKKLLALLCKGLFS----EASRTLPSLESIQKVFEQQLHPGIHQR
SQMLGEASPVNIVLKLNQLISLLSSIEEKVKTLLIEGPDSTHRRSLIPPVTFEV--KADS
LGIFSKIHLKVDVEMGKLIIKRAKDGPEDKFYTH---KKILQ-LIKSQKVPNKLVIMLET
EKEKTQRKEYVFSDSKKREGFCQLLQQMKNKHSEQPEPDMITVFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGAAPPPKKIT
S---WFLSK--GQGKTRDDTADYIPHDIYVIGTQEDPQGEKEWLETL--RQSLQ-EIT--
SISFKVIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSFGFVNSHLTSGSEKKHRRNQNYTSILRFLTLGDKKLSPFNITHRFTHLFWLGDLN
YRVEQPPTEAENIIQKIRQQQ-YPELLAFDQLLIERKDHKVFLQFE--------------
---------------------------EEEITFAPTYRFERGTREKYAYTKQKATGMKYN
LPSWCDRVLWKSYPMVHVVCQSYGCTTDITTSDHSPVFATFEVGVTSQFVSKN-----DS
KY---MNTQGEIEFLHCFATLKTKSQTKFYIEFHSSCLES-FVKSQEGENEDGSEGELVV
KFVDALPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRIEATESLVPIHTVLT
HHGEKTGVFQGEIKLQTSQGKQREKLYDFVKIERDE-IAGQKPKN-VNNLELNKDSDQLS
R-----KSKSTHLMAKEAAAIARYRGNASSSPDSLAKEDMLRCT-PTDISNPNYLGMAAF
PQQPFAASQLKQAPSPDQPSSLWNYEQQPKDSTSVMGQRESSSTSPSLSPLSPKPSLQTP
VSRSICNRSQ-DHLPPDLGKNTAEPL-LQEEG--QQKPEMFENPLYGYTASKGKAAPKKE
QDYPKASRKEQLPLPEQSFHLTKSQEPESSKSAS-K----QP----SPPFLVPTQRFRSY
TCSSQS---EEKSMG--EKTQGKLKAAPPSEN-S------ALLKKSVKPLRSEVGP-GVQ
GQ-----LSRPPLPSKSRAVLDMQSSKGRDYRDSSELPHASKHRIEEGP---LSRTATPV
CAL---------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDTGRQEVLLGT-------CFLPPRN-IPLPAG
---SCEAKEAPLSNENPRTTEASRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLICKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
LQAPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESSHRRSLIPPVTFEV--KSES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNALPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLCHDQLLTERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERYTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTTDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELLV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFQGEIKLQTSQGKKREKLYDFVKTERDE-ASGPKSLKSLTSHDPMKQWEPTS
RAP-PC-----------------------------------SGSSITEIINPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGSCRGEGPPTPPCQPPISPKKFLSST
ANRGLCPRTQE-SRPSDLGKNAGDGLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGLLSPSIVLTKVQESERSEGPAKQA----------PAPRLRSF
TCSSS---TEGRAAGGDK-SQGKPKTPANSQ-AP------VPAKRPIKPSRSEMNQQTL-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQV
GCAT--------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MPAMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIDF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDAIDEAEEDT--V-------ESVMSPPELPPRN-IPMSAG
---PSEAKDLPLATENPRAPEVTRLSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLL
LDSDFLKTGSSNLPHLKKLTSLLCKELHG----EVIRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEASPITMVAKLSQLTSLLSSIEDKVKSLLHEGSESTNRRSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIVKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLELL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YSDLLAHDQLLLERKDQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLETTEAQHPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGMKCLKNLTSHDPMRQWEPSG
RVP-AC-----------------------------------GVSSLNEMINPNYIGMGPF
GQPLHG--KS--TLSPDQQLTAWSYDQLPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGPCPRVQE-ARPGDLGK--VEALLQEDLL--LTKPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPPPCPDPGISSPSIVLPKAQEVESVKGTSKQA----PVPVLGPTPRIRSF
TCSSSA---EGRMTSGDK-SQGKPKASASSQ-AP------VPVKRPVKPSRSEMSQQ---
--TTPIPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHGKHRQEEGL---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------TPTMVSG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPVRYFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAGDEPEEDT----------ESVTSPPELPPRN-IPVSAG
---PCETKELPVPAENPRAPEASRPSLSETLFQRLQTMDTSGLPEEHLRAVQEYLGTQLA
LDSELAKTGSSSLPHLKKLISQLCKELHG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVAFEASPVNMVAKLSQLTSLLSSIEDKVKALLHEGPESPHWRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSDDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYIFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLR-EVT--
SMTFKPVAVHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDRKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAETIIQKIRQQQ-YTDLLAHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---GDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGAIKLQTSQGKKRERLYDFVKTERDE-PSGPKGLKNLSSQDPMKQWEPAG
RPT-PC-----------------------------------GALGLNDVMNPSYI---TF
GQPTRV--KLTMSPSLDQPLPAWSYDPLPKDSSLGPGRGDSPPTPPSQAPLSPKKFNSVA
ANRGTCPRAQE-SRPGELGKGASET-PQEDLP--LSKPEMFENPLYGSVSAFPKLVPRKE
QESPKMLRKEPPPCPES-------------EAEGSKGTSKPA----PTPFLSPAPRLRSF
TCSASP---EGRAASGDR-GQGKPKAPAGSQ-AP------VPAKRPIKPSRSEVSQQ---
---TPTPAPRPPLPAKSPAVLQLQHAKSRDYRDNCELPHHGKHRPEEGL---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESVVSPPELPPRN-IPLTAS
---SCEAKEVPPSNENPRATETSRPSLSETLFQRLQGMDTSGLPEEHLKAIQDYLSTQLA
QDSEFVKTGSSSLPHLKKLTTLQ-------------------------------------
------------------LTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--SGHG
TAEQ-----ELEVFSGKLHQPRGKDG----KVLS---SRILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKGVLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFAETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFRGEIKLQTSQGKTREKLYERSSSPEEV-L-------------SYVTLCLPC
RAP-PC-----------------------------------SGSSITEIINPNYMGVGPF
GPPMPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPCQPPISPKKFLPST
ANRGLPPRTQD-SRPSDLGKNAADTLPQEDLL--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQV----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTPVSSQ-AP------VPAKRPIKPSRSEMNQQTP-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQV
RRATRGLPCMCVCVC--------MRECVCLCLCICVCAHVYVRACVNACM---------C
THASDGPGNCSMR-RES--QDLNPGLPVPHIPDPALPLQQLLKGRKARLWINS-------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------YRNCVYTYRILPNE-DKFTVQASEGVPMRFFARLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAGDEPDEDTA---------ECVMSPPELPPRN-IPLSAG
---PCEAKEVPLLSESPRVPECSRRSLSETLLQRLQGMDTSGXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX--XXXXXXXXX--XXXX
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMXXXXXXXXXX
X---XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX-XXX--
XXXXXXMAVHSLWNMRIVVLAKPEHE---NRISHICTDHVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXEADLIIQKIKQQQ-YTDLLAHDQLLTERRERKVFLHFE--------------
---------------------------

PF03372 // ENSGT00760000119075_8_Domain_2 (868, 923)

EEEITFRPTYRFERLTRDKYVYTXXXXXXMKFN
LPSWCDRVLWKSYPLVHVVCQSYGXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XP
---GTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFEETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQFPIHTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-PCGSKILKSFTSHDPTKQLEPTL
RVP-LC-----------------------------------SGAGMTEILNPNYMGLGTL
GPPTAQ--HGKQAPP-GHQPTGLDYYPLSDAS--LGGRGGHPXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX-XX---XX--XXXXX-XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X-XXXXX----XXXXXXXXXXXXXX
XXXXXX--XXXXXXXXXXXXXXKPKPPAGARVLA------VPAQRPVKPSRSEMSQQALP
G------QHRPPLPVKSPAVLH-RHAKSRDYRDNSELPHHGKHRHEEGA---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MPAMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDAIDEAEED---T-------ESVMSPPELPPRN-IPMSAG
---PCEAKDPPLPIENPRAPEVTRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLNTQLV
LDSDFVKTGSSNLPHLKKLTSLLCKELHG----EVIRTLPSLESLQRLFDQQLSPGLRPR
PQVPSEANPINMVAKLSQLTSLLSSIEDKVKALLHEGSESPNRCSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YSDLLAHDQLLLERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALHLETTETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGMKCLKNLTSHDPMRQWEPAG
RVP-AC-----------------------------------GVSSLNEIINPNYIGV---
--PLHG--KS--TLSPDQQLTAWSYDQPPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGLCSRVQE-ARPSDLGK--VEALLQEDLQ--LTKPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPPPCPDPGISPPSILLPKAQEVEGVKGTSKQV----PVPVFGPTPRMRSF
TCSSSA---EGRMPSGDK-NQGKSKASAGSQ-AP------VPVKRPIKPSRSEMSQQ---
--TTPIPAPRPPLPVKSPAVLQLQHSKGRDYRDNSELPHHGKHRHEEGL---LGRTAMQV
R-----------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------PAMDQC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WYHGNITRSRAEDLLSKVGKDG
SFLVRASESIASAYALCVLYRNCVYTYRILPDKEKKLIVQASEGVPVKYFQNLEELIEY

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVWHLKYPVPREEEEAADELEED-T---------DLVPTPPVLPPRN-ILMALP
S---SETKEVSSLPENSRVAEVNKLSLSETLLQRLQYQDTSSVSDEHLKLIQDYLRVHIM
SDFEMVQTGSNNLPQLKKLLTALCKGLFS----EASRTLPSLESIQKVFEQQLHPSTHQR
SQMLGEASPVNIVLKLNQLISLLSSIEEKVKTLLIEGPDSTHRRSLIPPVTFEV--KTDS
LGIFSKIQLKVDVEMGKLIIKRSKDGPEDKFYTH---KKILQ-LIKSQKVPNKLVIVLET
EKEKTQRKEYVFSDSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGAAPAPKKIT
S---WFLSK--GQGRTRDDTADYIPHDIYVIGTQEDPQGEKEWLETL--RQSLQ-EIT--
SISFKVIAIHTLWNIRIVVLAKPEHE---NRISHICTANVKTGIANTLGNKGAVGV-SFM
FNGTSFGFVNSHLTSGSEKKHRRNQNYTNILRFLTLGDKKLSPFNITHRFTHLFWLGDLN
YRVEQPPTEAENIIQKIRQQQ-YPELLAFDQLLLERRDQKVFLQFE--------------
---------------------------EEEITFAPTYRFERGTREKYVYTKQKATGMKYN
LPSWCDRVLWKSYPMVHVVCQSYGCTTDIMTSDHSPVFATFEVGVTSQFVSKN-----DS
KY---TDSQGEIEFLHCYATLKTKSQTKFYIEFHSSCLES-FVKSQEGENEDGNEGELVV
KFVEALPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRIEATESLAPIHTVLT
HHGEKTGIFQGEIKLQTSQGKQREKLYDFVKIERDE-ITGQKPKN-ISNLEPNKDWDQTN
S-----WA------------------------------CCGSSI-NRYISNPNYLGMAAF
SQQPSATCQLKQTSSSEQAPSLWNYEQQSKENTSLMGQCQSSSTSPSLSPLSPKPSLQPT
ANRSICNWSQ-EYQLPDVGISIAEPV-LQEEG--QQRPEMFENPLYGSMGSRGKVAPKKE
QEYPKALRKEQPPLPEQSCHLTKPQEPECSKTSG-K----QP----SPPFLVPTQRFRSY
TSSCQL---EEKNIG--EKSQGKPKMTPPLEN-S------APLKKLIKPSRAEVSL-SIQ
GQ-----QNKPPLPSKSRAVLDMQNSKGRDYRDSSELPHSGKHRMEEGP---VSRTTTP-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDTGDEPE--E-ET-------EGAMSPPELPPRNIIPLSAG
---PCEAKEAPASMEIPRAAEVGRPSLSETLFQRLQAMDTSGIPEEHLKAIQDYLSTQLS
LDSDFVKSGSSSLPHLKKLTALLCKELYG----EVIRALPTLESLQRLFDQQLSPGLRPR
PQVPGEASPINMVAKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKLQLKVDVESGKLIIKKSKDSSEDKFYTH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSSFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YADLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERMTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---TDSQGQIEFLGCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGNIKLQTSQGKMREKLYDFVKTERDE-SSGPKSLKSLTSHDPMKQWEPP-
NRAPPC-----------------------------------SGSGITEIINPSYMGVGNF
GH-------LKQTLSPDQQPTAWSYDPPLKDSALGPGRGDSPPTPPSQPPISPKKFTSST
ATRGPCLT--Q-SRPSDVAKSVGETLPPEEPQ--LTKPEMFENPLYGSVSAFPKPAPRKE
QESPKMLRKEPPPCPDPGIVSPSILLSKVQEAEGSKGTGKPAP--PPAPFLSPTPRVRSF
TCST----SEGRPPGGDK-SQGKPKAPAGSQ-VPVP----VPVKRPIKPSRSELSQQPL-
--PA--QGQRPPLPVKSPAVLHLQHSKGRDYRDNAELPHHAKHRPEDAP---LSRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESVSRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPVRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 597)

Y
KKENMGLVTHLQYPVPLEEDDACDEPEEET--X-------XXXXXXXXXXXXX-XXXXXX
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLPKEHLKAIQDYLSTQLT
LDSDFVKSGSCSLPHLKKLTALLCKELYG----VQLRVIGWWMVELA----DMGGGKTNR
GH-------------------------------------YTSWELSHQPRKPRKRQGCIC
LGVIHALAL----EAGGKVTT---EGSAXXXXXX---XXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNAPPP

PF03372 // ENSGT00760000119075_8_Domain_1 (597, 941)

KKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTVAIHTLWNIRIAVLAKPEHE---NRISHVCTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSSFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YADLLAHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXFVKTERDE-SSVPKSLKSLTSQDPMKQWEPAN
RVP-PC-----------------------------------SGSSITEIINPNYMGVGAF
NY-------MKQTPSPDQQPTAWSYDQPLKDSSLGPGRGESPPTPPSQPPLSPKKFSSST
ATRGPCLRTQE-PRPGDVGKSAGEPLLPEDPQ--LTKPEMFENPLYGSVSAFPKPAPRKE
QESPKMLRKEPPPCPDPGILSPSILLSKAQEAEGSKGTGKPA----------PAPRLRSF
TCSSST--SEGRPPGGDKGSPGKSKAPAGSQ-VP------VPAKRPIKPSRSELSQQ---
--P---PVQRPPLPVKSPAVLHLQHSRGRDYRDNAELPHLAKHRPEDAP---PGRAAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MDQC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WYHGTITRSRAEDLLSKVGKDG
SFLVRASESISSAFALCLLYRKCVYTYRILPNKEDKLVIQASEGVPVQYFNNLDEVIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVRSLKYPVPREEEEATDELEDD-K---------DSMSMPPMLPPRI-SVPSLT
N---EA-VEDHFLDDYVQMTQVSKPSLSEILLQRLQQQDTSSIPEEHLRLIQDYLRVHMI
SDLETAQQGSWNLPQLKKLLSGLCKGLFS----EVSRILPSLESMQTVFDQQLSSGMHRH
SQPSYEAN----RTKLTQLTSVLASIEDKVKKMLVEGPDSTHRRSLIPPVTFEV--KADS
LGISPKIHLKVDVEMGKLIIKKAKDGPEDKFFTH---KRILQ-LIKSQKFPNKLVIVLET
EKEKTQRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGDAPPPKKIS
S---WFLSK--GQGKTRDDTADYIPHDIYVIGTQEDSLGEREWQEIL--RQSLQ-TIT--
SISFKVIAIHTLWNIRIVVLAKPEHE---NRISHLCIDNVKTGIANRLGNKGAVGV-SFM
FNGTSFGFVNSHLTSGSEKKQRRNQNFTSILRFLSLGDKKLNPFNITHRFTHLFWLGDLN
YRLELPPTEAENIIQKIKQQQ-YMELLNFDQLLIEKKDRKVFLQFE--------------
---------------------------EEEITFAPTYRFERHTRENYVYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGCATDIMTSDHSPVFATFEVAVTSQFVSKN-----DN
KC---TDSSGQIEFLHCSATLKTKSQTKFYIEFHSSCLES-FVKSKEGENEEGNEGELVV
TFVEALPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRSGATESQVPIQTILT
HHGEITGIFQGEFKLQTSQGKQREKLYDFVKIERDE-TSGQKTVK-G-CVDCITEWEQTN
RAA-LSNRKSTHLVAKEAAAIARFRGTPAVSLDEPCKEELLRSTAVTDINNPSYVRVPSA
SQSFPATGQLKQIPSPDQVPAFWSYDPQSKDSSSLMSLE-SPTTPSSLSPGSPRAPTQTT
TKRK-------DQLYSEVRKSMTEPL-LLEEA--FSKPEMIDNPLYDFGKSKDKLQSKRE
QEFFKAIRKELPVLPEQSFPFTNLQEGDAIKSSI-K---QQS----SLPFPAPAPRFRSY
TCSNQS---EEKTAL-IEKTQNRQRPCASSEPGV------PAFKKPVKFSRSEVG-----
-------QSKPPLPSKSQLVLDMQNLKGRDYRECSELPHNRKHQSEDVA---ISRTIVP-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRLFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
RKENMGLXXXXXXXXXXXXXX-XXXXXXXX--X-------XGVISPPELPPRN-IPLSTV
---PCEADSPSVSSESPRATEASRPSLSETLLQRLQNMDTSGLPEEHLRAIQDYVSTQLG
LDSDFARTGSSGLPHLRKT--VLCRELYGXXXIVPSXXXXXXXXXXXXXXXXX-------
------------------------------------------X--------XXX--XXXX
X--XX--XXXX--XXXXXX-----XXX---X------------------XXXXXXXXXXX
XXXXXXXXXXXXXXXXKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFVGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLETL--RQSLQ-EIT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXEAEAIIHKIRQQQ-YSELLCHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGDTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GA---ADRQGQVEFLRCYATLKTKSQTKFYLEFHSSCLEX-XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEGCIALRLEATETPLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SCGPKSLKSLTSHDPMKQWEPTS
RAP-AG-----------------------------------GGCALTEIINPNYMGVGPF
GH-------MKQTLSPDLQPTAWSYDPPLKESSLGPGRGESPPTPPSQPPISPKKFLCSV
TPRGPSSRTQE-------------------------------------------------
---------------------------------------------------APTPRLRSF
TCSSSS--T----ARGDKAQAKPRASAAGTP-AP------VPSKRPVKPSRSELSQPGQP
-APSPLPSTRPPLPVKSPAVLHLQHAKGRDYRDSSELPHHGKLRPEDTP---LGRAAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT---------VESVVSPPELPPRN-IPLTAS
---SCEAKEVSFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
QDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVIRTLPSLESLQRLFDQPLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEVTS
RAP-PC-----------------------------------SGSSITEIINPNYMGVGPF
GPPMPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPST
ANRGLPARTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSLSSFPKPAPRKD
QESPKMPRKEPLPCPEPGILSPSIVLTKAQEADRGEGPGKQV----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTPVSSQ-AP------VPAKRPIKPSRSEINQQTP-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-------MRKFSE----------------------AQFPFPRWVPETGSQSVKLWQQQQQ
QRRQQPPPRRPRGDGQQVPGV--AASRPGRPSATMVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAGDEPEED-T---------ESVVSPPELPPRN-IPLSAG
---PCEPKELPLLVENSRAPEVSRPSLSEMLLQRLQSMDTSGLPEEHLKAIQDYLSTQLP
LDSEFVKTGSGSLPHLKKLTTLLCRELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVRALALERRQNVKISELSSKFYSINENVKTLKKRGQSPPTRRSLIPPVTFEV--KSES
LGLPQKMHLKVDVESGKLIVKKSKDGSEDKFYSH---KKRLISLASSASFVLGRELLIET
TPGSTERREKPRSISQSAKKHCELFQLLSSIFRVPAQGPQVGMTLGTKWAEATLDETVRC
T---WLLAL--GTSRCRSSAPPHHPCC-NTQSQGSQTQGQPEWETVL--QRHPQ-HQKVS
TLGSKRVSAHRRIGRAMLLRSQPANWRPQSKVSGVPRKTIATSSLMSLEHRGRPAL-GRK
FLGGELFKIDGFLDDRAEKPPR----KTSLSGLETTGSEDRSPWGSLRGSHRVKWLGHTE
KKWEMTTWAVCSVLQLIKSQK-FLNKLVKRKTCGNRAAEPLFILCW--------------
---------------------------SDPATEAV----HRGSRA------ESEARLLHQ
RGSACELALSKAFPLVHLDTHLRGSAAWALSLA------REEAAGRGWL---E-----AP
LRPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGESLPKLTPIISDPEYLLDQHVLISIKSCDSDESYGEGCIALRLEATETPLATHTPLT
HHGEMTGHFHGEIKLQTAQGKKREKLYDFVKTERDD-TSGLKSLKSLTSHDPMKQWEPAS
RAP-PC-----------------------------------SGSNITEIINPNYMGMGPF
GQPAPL--PGKQTLSPDQQLTAWSYDQPPKDSSLGPGRGESPPTPPSQPPLSPKKFSSSV
ANRGPCLRTQE-SRPGDLGKSTADASAHEDLQ--PSKPEMFENPLYGSVSAFPKPAPRKE
QESPKPLRKEPPACPDPALLSPSIVLTKAQEAEGSKGPGKQG----PVPFLSPAPRLRSF
TCSSSA--AEGRP-ASGDKSQGKPKAPASSQ-AP------VPAKRPIKPSRSEMGQQPAA
TPIPPTPSPRPPLPIKSPAVLHLQHSKGRDYRENTELPHHGKHRPEEAP---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDAGDEPEEDTA---------ESITSPPELPPRN-ILLPQG
---LCDAKEFPASLESARAPEVNRPSPSETLLQRLQTVDTSGLPEEHLKAIQDYLSTQLL
LDLEFVKTGSGSLPHLKKLTTLLCKELYSEAAITLMA----IEQETAKLS-SLLPDWK--
-------------------------------WTERAGHEPPQRPG---GCVREL-----C
WAAPK---------AGVRVIXXXXXXXXXXX------------------XXXXXXXXXXX
XXXXXXXXXXXXXXXXKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDTADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EIT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YTDLLSHDQLLTERKEQKVFLHFE--------------
-----------------------------------------LTRDRYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDGQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETPLPIHTPLT
HHGEMTGHFRGEIKLQTSQGKKREKLYDFVKTERDD-SSGLKSLRNFSSHDSGKQWEPAG
RAP-PC-----------------------------------SGPNITEIINPNYMGVGPF
GQPMPL--HVKQMLSPDQQLTAWSYDQLPKDSSLGPGRGDSPPTPPSQPPLSPKKFSSSA
TNRGPCPRVQE-ARPGDLGKNTAEACPQEDLQ--PTKPEMFENPLYGSVNSFPKPIPRKE
QESPKLLRKEPPSCLDSGLQSPSIVLTKAQEGEGGKGPGKQA----------PAPRLRSF
TCSSSA---EGRVASGDK-SQGKPKAPASSQ-AP------VPAKRPIKPSRSEMSQQSGS
LSMPPTPSPRPPLPVKSPAVLHLQHSKSRDYRENTELPHHGKHRPEEGP---LSRTTMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESVVSPPELPPRN-IPPSAG
---SCEAKEVPLSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAISSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNSELPHHGKHRPEEGPPGPLSRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------TPTMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGRDG
SFLVRASESISRAFALCVLYRNCVYTYRILPSEEDKFTVQASEGVPVRYFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAGDDPEEDT--V-------ESVTSPPELPPRN-IPFSAG
---PCETKELPVPAENLRAPEASRPSLSETLFQRLQTMDTSGLPEEHLKAIQEYLSSQLA
LDSDFVKTGSSSLPHLKKLTSQLCKELHG----EVVRTLPSLESLQRLFDQQLSPGLRPR
AQVPCEASPASMVAKLSQLTSLLSSIEDKVKALLHEGPEPPHWRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDSSDDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTSNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAEAIIHKIRQQQ-YADLLAHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPVYTPLT
HIGEMTGHFQGAIKLQTSQGKKREKLYDFVKTERDE-PSGPKCLKSLTSHDSMKQWEPAA
RAP-LC-----------------------------------SAPSITDIVNPSYIGVGPF
GQPLHP--KLALSPTLDQPFPAWSYDPLPKDSSLGLGRGDSPPTPPSQPPLSPKKLASAM
ANRGPCPRAQE-PRPSELGKGAAEA-LQEDLP--LTKPEMFENPLYGSVSTFPKLVPRKE
QESPKMLRKEPPPCPEPTAMLPSVLLPKAPEAEGSKGIAKQA----STPFLSPAPRLRSF
TCSASP---EPRAAGGDR-SQGKPKGPAGSQ-AP------VAAKRPIKPSRSEVSQQ---
--STPTPALRPPLPVKSPAVLQLQHAKGRDYRDNSEFPHHGKHRPEEGL---LGRTTMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MSTMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESIPRAHALCVLYRNCVYTYRILPNDDDKLTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAVDEAEED---M-------ENTMSPPELPPRN-IPTTAG
---LCEAKELPLAAESPRAPEVSRPSLSETLFQRLQNMDTSGLPEEHLKAIQDYLSNQLT
LDSDFLKTGSSNLPHLKKLTSLLCKELHG----EVVRTLPSLESLQKLFDQQLSPSLRPR
PQVSSEASPINMVAKLSQLTSLLSSIEDKVKALLHEGSESPHRRSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSERPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDSVKTGIANALGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSSFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YVELLSHDQLLMERKAQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGIKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VGSQGQIEFLTCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSDGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCVALRLEATETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKKREKLYDFVKTERDE-SIGAKCLKSLTSHDPMRQWEPSI
RAP-AC-----------------------------------GVPSLSEIINPNYMGMGPF
GQPTLG--KP--TLSPDQQPTAWSYDQPPKDSSLGPGRGEGPLTPPSQPPLSPKKFSSST
ANRCPCPRMQE-TRPGDLGKSPTEALLQEDAP--LTKPEMFENPLYGSMSCFPKLVPRKE
QESPKMPRKEAPPCPEPGISSPSILLTKAQEAEGSKGTGKQA----PVSAFGPTPRVRSF
TCSSSA---EGRPSSGDK-GPGKPKAPASSP-AP------VPAKRPIKPSRSEVSPQ---
--TTPSPAPRPPLPVKSPAVLQLQYSKGRDYRDNTELPHHGKPRPEEGL---LGRTAMQV
WWAT----R--ARVR--------ARA------CVRVHASVVVLGRAGLQA----------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------ECVPSPPELPPRN-IPLSSG
---PCEAKELPVSGENGRVAEASRPTLSETLLQRLQSMDSSGLPEEHLKAIQDYLNTQLC
LDSEFVRTGSSSLPHLKKLTMLLCKELYGYASALPRIM-G----------RXXXXXXXXX
XXXXXXXXXXXXXX-------------------------XXXXXXX----XXXX--XXXX
X--XX--XXXXXXXXXXXXX----XXXXXXXXXX-VRRHFLK-TLD--AYCQIALLDIHT
NLGSS-LTKCFQGDVRKREGFCQLLQQMKNRHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMAPPPE---IT
------SLK--GQGKTRDDSADYLPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EIT--
SMTFKTIAIHTLWN-RIVVLAKPEHE---NRISHICTDNVKTGIANTLXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXEAETIIQKIKQQQ-YADLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYAMLKTKSQTKFYLEFHSSCLES-FVKSLEGENEEGREGELVV
KFGESLPKLTPIISDPEYLLDQHILISIKSSDSDESY-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MSYG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WYHGNITRSKAEDLLSQAGKDG
SYLVRDSESVCRAYALCVLNQSCVHTYRILQNAEQQLSVQASEGVPMRFFTNLVELIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
RRENVGLVTHLKYPIEKEEEGPEEP----DE---------EQEPAPPNVPPRN-FAFTPV
S----EIKECQTAIERA-PAANASLLLSETFLQRFQDTDSRCIPEEHLQAIRDYFSLHVV
SDCDMVRSGSQSLPQFKKLLMTLCTGLHR----ELTRTLPTLESLQVTFDPQLSPGFRQR
SPLPGDSATNNMVNKLTHLTSMVSGLEEKVKTVLMEGAAVKHRRSLIPPIIFEV--KADS
LGISQKTHLKVDVETGKLIIKKSKDGPDDKFYPS---KKILQ-LIKSQKFPNKLVIVLET
EKEKTQRKEYVFADSKKREGFCQLLQQMKNKHSGQSEPDMLS

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTYNMGDAPPPKNIT
P---WFLCK--GQGKTRDDTADYIEHDIYVIGTQEDPLSEKEWTDIL--MNSLR-EIT--
SVEYKVITIQTLWNIRIVVLAKPEHA---HRISHVFTNSVKTGIANTLGNKGAVGA-AFM
FNGTSFGFINSHLTSGSEKKLRRNQNYFNILRFLILGDKKLSPFNLTHRFTHLFWLGDLN
YRLQLPNTEAENIIQKIKQQQ-YQELLAHDQLNLERKENLIFFQFG--------------
---------------------------KLVDTYYIRCRYAGLLLVYYCLSTNVQNNIKYN
LPSWCDRVLWKSYPHMHILCQSYGCTDDITTSDHSPVFCTFQVGVTSQFVSKN-----NP
GNSGDLEAQGHIELMNCRATLYTKSHTKFYIEFHSPCLEN-MVKSSEAEDQEGNNGTLVV
KFG-VLPKLTPIISDLEYLLDQHLLICIKSSDTDESYGEGCIALRKEDTEQQFQFSTILT
HHGEETGLFCGEICLLASGGKQREKLYDFVKIEKDE-TVAQKQLKHPYSQAM--------
-----EQSRIMKSISEKSAMMARMRGVPVCPSETQNSMDHTASV-------------AAI
------SSQPKQS-PPTTPPGFKASEQRQKPGSPVLGRGDTPLTPPPRTTLSNQKFPHPN
TTRAPPAARQQDSL-------------RITIP--SDPHEMVDNPLYGPINNSLYPPPA--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT---------VESVVSPPELPPRN-IPLTAS
---SCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
QDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVIRTLPSLESLQRLFDQPLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEVTS
RAP-PC-----------------------------------SGSSITEIINPNYMGVGPF
GPPMPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPST
ANRGLPARTQE-SRPSDLGKNAGDTLPQEDLP--LMKPEMFENPLYGSLSSFPKPAPRKD
QESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQV----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTPVSSQ-AP------VPAKRPIKPSRSEINQQTP-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MDQC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WYHGNITRSRAEDLLSKVGKDG
SFLVRASESIASAYALCVLYRNCVYTYRILPDKENKLIVQASEGVPVKYFQNLEELIEY

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVWHLKYPVPREEEEAADELEED-T---------DLVPTPPVLPPRN-ILMALP
S---SETKEVSSLPENSRVADVNKLSLPETLLQRLQCQDTSSVSDEHLKLIQDYLRVHII
SDLEMVQTGSSNLPQLKKLLTALCKGLFS----EASRTLPSLESIQKVFEQQLHPGTHQR
SQMLGEASPVNIVLKLNQLISLLSSIEEKVKTLLIEGPDSTHRRSLIPPVTFEV--KTDS
LGIFSKMQLKVDVEMGKLIIKRSKDGPEDKFYTH---KKILQ-LIKSQKLPNKLVIVLET
EKEKTQRKEYVFSDSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGAAPAPKKIT
S---WFLSK--GQGRTRDDTADYIPHDIYVIGTQEDPQGEKEWLETL--RQSLQ-EIT--
SISFKVIAIHTLWNIRIVVLAKPEHE---NRISHICTANVKTGIANTLGNKGAVGV-SFM
FNGTSFGFVNSHLTSGSEKKHRRNQNYTNILRFLTLGDKKLSPFNITHRFTHLFWLGDLN
YRVEQPPTEAENIIQKIRQQQ-YPELLAFDQLLLERRDEKVFLQFE--------------
---------------------------EEEITFAPTYRFERGTREKYAYTKQKATGMKYN
LPSWCDRVLWKSYPMVHVVCQSYGCTTDIMTSDHSPVFATFEVGVTSQFVSKN-----DS
KY---TDSQGEIEFLHCYATLKTKSQTKFYIEFHSSCLES-FVKSQEGENEDGNEGELVV
KFVEALPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRTEATESLAPIHTVLT
HHGEKTGIFQGEIKLQTSQGKQREKLYDFVKIERDE-ITGQKPKN-ISNLEPNKDWDQTH
R-----KSKSTNLMAREAAAIARHWGSAVPSPDSLAKEDILRST-PTDISNPNYLGMAAF
SQQLSASCQLKQTPSSEQAPSLWNYEQQSKENTSLMGQSQSSSTSPSLSPLSPKPSLQPT
ANRSICIRSHSEYQPPDVGKCTAEPV-LQEEG--QQRPEMFENPLYGSMSSKGKVAPKKE
QEYPKALRKEQPPLPEQSCHLTKPQEPECSKTSG-K----QP----SPPFLVPTQRFRSY
TSSCQL---EEKNSG--EKSQGKPKISTPLEN-S------APLKKLMKPSRAEVSL-SIQ
GQ-----Q-KPPLPSKSRAVLDMQNSKGRDYRDSSELPHSGKHRLEEGP---VSRTATP-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESVLSPPELPPRN-IPLSAG
---SCEAKEAPLSNENPRATEASRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLT
LDSEFVKTGSSSLPHLKKLTTLLCRELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
LQAPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEVNP---G
LGLPNWARE-----------------TCSGFCGNGDWGLILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEH-------------------------
---------------------------------------EKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLCHDQLLTERKEQKVFLYFE--------------
---------------------------EEEITFAPTYRFERYTRDKYAYTKQKATGVTNG
QPHLCPAVSWKNNP---------CTTTDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-----EEGWNEEESRASPV-
P---FSLQLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFQGEIKLQTSQGKKREKLYDFVKTERDE-ASGPKSLKNLTSHDPMKQWEPAS
RTP-PC-----------------------------------SGSNITEIINPNYMGVVP-
-----L--HVKQTLSPEQQPTAWSYDQPPKDSPLGSCRGEGPPTPPCQPPISPKKFSSST
ANRVLCPRTQE-SRPSDLGKNAGDGLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGLLSPSIVLTKVQEAERSEGPAKQA----------PMPRLRSF
TCSSST---EGRAAGGDK-SQGKPKTPANSQ-AP------VPAKRPIKPSRSEMNQQTV-
----PTLTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEDGPPGPVGRTAMQV
RCATRGLVCMCVHVHA--------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------RPPWSPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELL-RTGKDG
SFLVRASESIPRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDTGDEPEEETGGV-------EGVPAPPELPPRN-IPLSAG
---PCEAKEVPLLSENLRATEVSRPSLPETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLT
LDADFVKTGSSSLPHLRKLTVLLCKELYG----EVTRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANLINMVTKLSQLTSLLSSIEDKVKALLHEGPESSHRRSLIPPVTFEV--KSES
LALPQKLQLKVDVETGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTVRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDP-GEKEWLEIL--KNSLQ-EIT--
SITFKMIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEPMIQKIKQQQ-YAELLCHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERMTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFAT

ENSGT00760000119075_8_Linker_1_3 (941, 1348)

FEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCFATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGPKCLKSLTSHDPMKQWEPA-
SRVPLC-----------------------------------SGSSVTEIINPNYMGVGSF
GY-------IKQNLSPDQQPTAWSYDQPLKDSSLGSGRGETPPTPPSQPPISPKKFSSSI
ATRGPCPRTQE-SRPSDLGKNAVEPLPQEDPK--LTKPEMFENPLYGSVCAFSKLVPRKE
QESPKMLKKELPPCPDPGSLSPNILLS

PF00807 // ENSGT00760000119075_8_Domain_3 (1348, 1378)

KAQEPEGNKGTGKPVPIPAPTPFISPAPRLRSF
TCSSP---AEGRPAAGDK-SQGKPKAPASS-------PAPVPAKRPIKPSRSELSQQAP-
--PTP--AQRPPLPLKSPAVLHLQHSKGRDYRENAELPHHGKHRPDDTP---LSRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVLG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDPAEDPEED-T---------ESVMSPPELPPRN-IPPPAG
PCGPCEAKEPPPLVETPRGTEVSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSDFVKMGSSSLPHLKKLTSLLCKELHG----EVTRTLPSLESLQRLFDQQLSPGLRSR
LQVPGEASPITMVAKLSQLMGLLSSIEDKVKALLHEGSEAPHRRSLIPPVTFEV--KSES
LGIPQKIHLKVDVESGKLIVKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EIT--
SITFKTMAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-FADLLAHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGCTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VNSQGQIEFIACCATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGHEGELVV
RFDETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEAIETQMPIYTSLT
HHGEMMGHFRGEIKLQTSQGKKREKLYDFVKTERDE-SSGTKCLKSLTSHDPVKQWEPPS
RAP-PS-----------------------------------GASGFTEIINPNYMGVGRF
GQPLHG----KQSLSPDQQLTAWSYDQQPKDPSLGPGRGEGPLTPPSQPPLSPKKFSSST
ANRGPCPRAQDSRS-------TDTQL-QEDLQ--LAKPEMFENPLYGSVSSFPKLVTRKE
QETSKMPPKEPPPCPDPGIASPSILLTKAQETEG-S---KQA----PTPFLSPAPRLRSF
TCSSST---TEGRMTSGDKNQGKPKTLAVSH-AP------VPAKRPIKPSRSDMSQQGTP
TP-----APRPPLPAKSLAVLQLQHSKARDYRDNTELPHH-KHRPEDAV---LGRTAMQV
CSNA--------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVSS

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDRFTVQASEGVPVRYFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAGDDPEEDT----------ESVASPPELPPRN-IPLSTG
---PCETKELLGPAENPRAPEASRPSLSETLFQRLQTMDTSGLPEEHLRAIQEYLGTQLA
LDSEFAKTGSSSLPSLKKLISQLCKELHG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPCEASPVTMVAKLSQLTSLLSSIEDKVKALLHEGPESPHWRSLIPPVTFEV--KAES
LGIPQKLQLKVDVESGKLIIKKSKDGSDDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYIFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLR-EVT--
SMNFKPIAVHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDRKLSSFNITHRFTHLFWLGDLN
YRVDLPTWEAEAIIQKIRQQQ-YADLLAHDQLLTERKEQRVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---GDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGAIKLQTSQGKKREKLYDFVKTERDE-PSGPKCPKSLTIQDPVKQWEPRR
GPP-CQ-----------------------------------ASFGLTDIMNPSYI---PV
RQPVTA--KLPMSPLPDQPLPAWGYDPQPKDPSLGPGRGDSPPTPPSQPPLSPKKFTSAS
ANRGPCPRVQE-SRPSEQGKGSTEA-PQEDLL--LSKPEMFENPLYGSVSAFPKLVPRKE
QESPKMLRKEPTPCPEPSI-----SFSKAPEAEGSKGPGKQA----PTTFLSPAPRLRSF
TCSAST---EGKATSGDR-GQGKPKGPASSQ-AP------VPAKRPIKPSRSEVSQQ---
--PTPTPAPRPPLPVKSPAVLQLQHAKSRDYRDNSELPHHGKHRPEEGL---LGRTAMQV
SVST----S--VC------------A------CVHARSHPRGY--------------SVS
VCAENIPEP--FLTK---------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEEAGDEPEEETE----------GVLSPPELPPRN-IPLFAG
---PCETKDVPLSSENVRATEVSKPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSDFVKTGSSSLPHLKKLTTLLCKELYG----EVLRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPVNMVAKLSQLTSLLSSIEDKVKALLHEGAESPHRRSLIPPVTFEV--KSES
LGIPQKLQLKVDVESGKLIMKKGKDGSEDKFYPH---NKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIVQKIKQQQ-YADLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCFATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGPKSLKSLTSHDPMKQWEPA-
NRVPSS-----------------------------------GSSSITEIINPNYIGVVPF
GH-------MKQSLSPDQQPTAWSYDQPLKDSSLGPGRGDSPPTPPSQPPVSPKKFSSST
ATRVPCPRTQE-SRSCDVGKNPAEPSPPEDAQ--LTKPEMFENPLYGSVSSFPKPLPRKE
QESPKMLRKEALPCPDPGIVSPSILLPKAQEAEGNKGTGKPT----PTPFLSPTPRLRSF
TCSSS---AEGRPAGGDK-SQGKAKAPASLH-A------QVPAKRPIKPSRSELSPQAP-
--PPPPLAQRPPLPVKSPAVLHLQHSKGRDYRENAELPHHGKHRPEDAP---LSRAAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLXXXXXXXXXXXXXX---------ESITSPPELPPRN-IPQSSG
---PCEAKEAPLCVENSRVTEVSRPSLSETLFQRLQTMDTSGXXXXXXXXXXXXXXXXXX
XXXXXXX--------------------------------------XXXXXXXXXXXX---
---------------------------------------------XX-------------
----XXXXXXXX-------------------------------------XXXQTVL----
-----LP---KANQYVKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMXXXXXXKKIT
P---C---S--SKGQKTRDDADYIPHDIYVISTQENPL-EKEWLEIL--RHSLQ-EIT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YADLLSHDQLLAERREQKV-------------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXTSDIMTSDHSPVFATFEAGVTSQFVSKN-----XX
XXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXX-FVKSQEGENEDGSEGELVV
KFGETLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXFVKTERDE-SSGPRSLKSLTSHDPMKQWEPSN
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDTGDEKGWRE-RA-------LGAMSPPELPPRNIIPLSVG
---PCEAKEAPASMEIPRAAEVSRPSLSETLFQRLQAMDTSGIPEEHLKAIQDYLSTQLS
LDSDFVKSGSSSLPHLKKLTALLCKELYG----EVIRALPTLESLQRLFDQQLSPGLRPR
PQVPGEASPINMVAKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKLQLKVDVESGKLIIKKSKDSSEDKFYTH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSSFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YADLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERMTRDKYAYTKQKATGVNFQ
AWLW------E---LISAV----CSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---TDSQGQIEFLGCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGDIKLQTSQGKMREKLYDFVKTERDE-SSGPKSLKSLTSHDPMKQWEPA-
NRAPPC-----------------------------------SGSGITEIINPSYMGVGNF
GH-------LKQTLSPDQQPTAWSYDPPLKDSALGPGRGDSPPTPPSQPPISPKKFTSST
ATRGPCLT--Q-SRPSDVAKSVGEPLPPEEPQ--LTKPEMFENPLYGSVSAFPKPAPRKE
QESPKMLRKEPPPCPDPGIISPSILLSKVQEAEGSKGTGKPAP--PPAPFLSPTPRVRSF
TCST----SEGRPPGGDK-SQGKPKAPAGSQ-VPVP----VPVKRPIKPSRSELSQQPL-
--PA--QGQRPPLPVKSPAVLHLQHSKGRDYRDNAELPHHAKYRPEDAP---LSRTAMQV
RSGR-------VGRR--------VRM------RGC-ALQVRV-----------------R
ACE---------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVHC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSKTGKDG
SFLVRASESISRAYALCVLFRNCVYTYRILTNEEEKFTVQASEGVPVRFFTSLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEEAGDEVEEETX---------XXXXXXXXXXXXX-XXXXXX
XX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLPEEHLKAIQDYVNTQIT
MDAEFVKTGSSNLPHLKKLVMVLCKELYX----XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX----XXXX--X----------------XXXXX-----XXXXXXXX-------
----XXXXXXXXXXXXXXXX---------X-----------X-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXVQKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGDAAPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
DISFKTIAIHTLWNIRIVVLAKSEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRLELPPSXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX--------------
---------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GN---VDSQGQIEFLKCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGTEGELVV
KFADDLPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRSEATESLVPIYTALT
HHGEMMGHFRGEIKLQTSQGKKRERLYDFVKTERDE-ASGQKSLKSLTSHDPLKHWXXXX
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX----------XXX----XXX-XXXXXXXX
X-------X-XXX-XXX--XXXXXX----------------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXPSDLGKNMADPLPVEEVQ--MTKPEMFENPLYGSVSPFPKPMPRK-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MLLCKELYG----EVVRTLPSLESLQRLFDQQLSPALRPR
TQVPGEPNLISMVAKLSQLTSLLSSIEDKVKALLHEGPEPTHRRSLIPPVTFEV--KAES
LGISQKMQLKVDVESGKVIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFHNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDALGEKEWLELL--KHSLQ-EVT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRLELPVSEAETIIQKIKQQQ-YADLLSHDQLLLERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTREKYAYTKQKATGMKYN
LPSWCDRVLWKSYPRVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSLEGENEEGREGELVV
KFGETLPKLTPIISDPEYLLDQHILISVKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFQGEIKLQTSQGKMREKLYDFVKTERDE-PSGPKSLKSFSSHDPMKLWEPAN
RTP-LC-----------------------------------TGSSINEIINPSYTGVGPF
GSLMPL--HVKQTLAPEQQPPTWSCDPPPKDSSLGPGRGEGSPTSPSQAPVSPKKFSSSS
ANWSPCPWAQE-SRSSDMGKNMAEPLLPEDLP--LTTPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPPPCPDLGTPSPSILLTKAQEAESTKGAGKQN----APPFLSPAPRLRSF
TCSSSA---EGRA-AGGDKNQGRPKPPASAQ-AP------VPAKRPIKPSRSETSQ---P
AP-----TQRPPLPVKSPAVLHLQHAKGRDYRENTELPHHGKHRPEEGP---LGRTAAQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 228)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQWGHSWGSVTWVPWPGPHRVV
GNAWDGVMHTVSSPMAF--------LLLSW--A-------ESIVSPPELPPRN-IPLSAG
---PCEAKELPPSIENPRAPEVSRPSLSEMLLQRLQNMDTTSE--EKMGRLEPVLSCQFF
MRKTALKQGP----ELSHLMTHLSAQPTGSLSAAPLPSLKWAHA-----QRRRPRGLCLL
RQVPCEANPISMVSKLSQLTSLLSSIEDKVKALLHDGPESSHRRSLIPPVTFEVSGCGAA
E--P---GLVLHSWGLGLLWSLWKEGFGLGLWGH-KEPKVLQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSK----FCPLSQAQK-------------------------DGDKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RQSLQ-EIT--
SVTFKTVAIHTLWNIRMVVLAKPEHE---NRISHICTDTVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIHTPLT
HHGEMTGHFRGEIKLQTSQGKKREKLYDFVKTERDE-ASGQKSLRSLTSHDPMKQWEPAG
RAP-PC-----------------------------------GGSSITEIMNPNYMGVGPF
GQPTSL--HGKQILSPDQQPTAWSYDQPPKDSSLGPGRGDNPPTPPCQPPLSPKKFSSST
ANRGPCLRTQE-SRPGDLGKSGAEALLPEDLP--LTKPEMFENPLYGSVSSFPKPAPRKE
QESPKMLRKEPPPCPDLGLLSPSVALTKAQEAERSEGTGKQV----------PAPRLRSF
TCSAPA---EGRAATGDK-SQGKPKAPAGSQ-AP------VPAKRPIKPSRSEMSQQ---
--TPPAP-TRPPLPIKSPAVLHLQHSKGRDYRDNSELPHHGKHRTEEGP---LSRTAAQV
CARL----H--VGSH--------ARV------CARVCAHGRVI------------VLGAA
PCGRAGVRI---------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDTGDEPE--E-ET-------EGAVSPPELPPRNIIPLPAG
---TCEAKEAPASTENPRAAEVGRPSLSETLFQRLQTMDTSGIPEEHLKAIQDYLSTQLS
LDSDFVKSGSSSLPHLKKLTALLCKELYG----EVIRALPTLESLQRLFDQQLSPGLRPR
PQVPGEASPINMVAKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKLQLKVDVESGKLIIKKSKDSSEDKFYTH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EVT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSSFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIRQQQ-YADLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERMTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---TDSQGQIEFLGCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGNIKLQTSQGKMREKLYDFVKTERDE-SSGPKSLKSLTSHDPMKQWEPA-
NRVPPC-----------------------------------SSSSITEIINPSYMGVGNF
GH-------LKQTLSPDQQPTAWSYDPPLKDSTLGPGRGESPPTPPSQPPVSPKKFTSST
AMRGPCLRTQE-SRPSDVVKSVAEPSPPEELQ--LTKPEMFENPLYGSVSAFPKPAPRKE
QESPKMLRKEPPPCPDPGIMSPSILLSKAQEAEGSKGTGKPVP--PPAPFLSPTPRVRSF
TCST----SEGRPPGGDK-SQGKPKTPAGSQ-VPVPVPVPVPVKRPIKPSRSELSQQPL-
--PA--QGQRPPLPVKSPAVLHLQHSKSRDYRDNAELPHHAKHRPEDAP---LSRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT---------VESVVSPPELPPRN-IPLTAS
---SCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
QDSEFVKTGSSSLPHLKKLTTLLCKELYL-------------------------------
------------------------------------------------------------
-----------------------------------------Q-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SLM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEVTS
RAP-QC-----------------------------------SGSSITEIINPNYMGVGPF
GPPMPL--HMKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSLSSFPKPAPRKD
QESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEVPGKQV----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTPVSSQ-AP------VPAKRPIKPSRSEINQQTP-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT---------VESVVSPPELPPRN-IPLSAG
---SCEAKEVPLSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKTQLKVDVESGKLIVKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERKEQKVFLHFE--------------
---------------------------EEEIHVCPTYPCD------------FDLQMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEASEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFRGEIKLQTSQGKTREKLYDFVKTERDE-SSGQKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAVSSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNTELPHHGKHRPEEGPPGPLSRTAMQV
RGATRGLVCMCVCVHA--------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESIVSPPELPPRN-IPPSAG
---SCEAKEVPLSNENPRATETSRPSLSETLFQRLQSMDTNCILKAQKN----VEAPQFS
F-----------------DALRMVEGGSG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAISSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNSELPHHGKHRLEEGPPGPLSRTAMQV
RGATRGLVCMCARVHA--------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEEAGDEPEEE-T---------AEVPSPPELPPRN-ILLSAG
---PCEAKEAPLLSENPRATEFNRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLT
LDSDFMKTGSTSLPHLKKLTVFLCKELYG----SSAAILRTLRQIVEVAG--LLSGWTG-
-----------------------------------GGSMNRGRY-SASPQQRGW--KGRL
RGYTFGMPLKA----GTVGES--------HVRS--------H-LTSDTYFPLTL-PEVRT
DLRPSLTKP-FECNQQKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KNSLQ-EIT--
SMTFKTITIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YVDLLSHDQLLMERKDQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYXXXXXXXXSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSRGQIEFLKCYATRKTKSQTKLYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISVKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKKREKLYDFVKTERDE-SSGPKQKS-LTSHDPAKQWEPAN
RVP-LC-----------------------------------SGSSITEIINPSYMGVGPF
T-------HMKQALSPEQQPTAWSYDQPFKDPSLGPGRGESPPTPPSQPPISPKKFSPAT
TSRSPCPRTQE-SRPSDVGKNTXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX---X-XXXXXXXXXXXXXXXXXXX-X---XXX----XXXXXXXXXXXXXX
XXXXXX--XXXXXXXXXXXXQGKPKAPASSQ-AP------VPAKRPIKPSRSELSQQAPP
TP-----AQRPPLPVKSPAVV-LQHSKGRDYRENAELPHHGKHRPEDSP---LGRAALQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

MGRGLDWTVPPAPNFAGLRGGRAVAQREAQGEGRPDGAGTRVGGPCRRASCAPVTCGRPG
PPPRPPARRRPREARGGVGRWSSLPALSQGGSSRGRRLPLPRRAPEQEVAGRAGLH----
--RAAGGAARGAARGPRLPSEARARGAGRPPEARHGPLLEPRQHHPLQGQELLSRTGKKR
IFFVRARDSISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAGDEPEEETE----------GVLSPPELPPRN-IPLSAG
---LCEAKEVPLLSENLRATEVSRPSFSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSDFVKTGSSSLPHLKKLTMVLCKDLYG----EVIRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVAKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KSES
LGIPQKLQLKVDVESGKLIIKKSKDGSEDKFYTH---NKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIVQKIKQQQ-YADLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCFATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGTKSLKSLTSHDPMKQWEPA-
NRVPPC-----------------------------------SGTNITEIINPNYMGVVPF
GH-------MKQSLSPDQQPTAWSYDQPLKDSSLGPGRGESPPTPPSQPPVSPKKFSSST
ATRGPCPRTQE-SRPCDLGKSTPESSPQEDVR--LTKPEMFENPLYGSVSSFPKLLPRKE
QESPKMLRKDPPPCPDPGILSPGILLPKAQEAEGTKGTGKAAA---AAPFLSPTPRLRSY
TCSSS---AEGRPAAADK-SQGKAKAAAGLQ-A------QVPAKRPIKPSRSELSQQPP-
--PPP--AQRPPLPVKSPAVLHLQHSKGRDYRENAELPHHGKLRAEDAP---LGRASMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MPAMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDAIDEAEEDT--V-------ESVMSPPELPPRN-IPMSAG
---PSEAKDLPLATENTRAPEVTRLSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLL
LDSDFLKTGSSNLPHLKKLTSLLCKELHG----EVIRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEASPITMVAKLSQLTSLLSSIEDKVKSLLHEGSESTNRRSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIVKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLELL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDTVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YSDLLAHDQLLLERKDQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLETTEAQHPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGMKCLKNLTSHDPTRQWEPSG
RVP-AC-----------------------------------GVSGLNEIINPNYIGMGPF
GQPLHG--KS--TLSPDQQLTAWSYDQLPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGPCPRVQE-ARPGDLGK--VEALLQEDLL--LTKPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPPPCPDPGISSPSIVPPKAQEVESVKGTSKQA----PVPVLGPTPRIRSF
TCSSSA---EGRMTSGDK-SQGKPKASASSQ-AP------VPVKRPVKPSRSEMSQQ---
--TTPIPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHGKHRQEEGL---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGRDG
SFLVRASESISRAFALCVLYRNCVYTYRILPSEEDKFTVQASEGVPVRYFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAGDDPEEDT----------ESVTSPPELPPRN-IPFSAG
---PCETKELPVPAENLRAPEASRPSLSETLFQRLQTMDTSGLPEEHLKAIQEYLSSQLA
LDSDFVKTGSSSLPHLKKLTSQLCKELHG----EVVRTLPSLESLQRLFDQQLSPGLRPR
AQVPCEASPASMVAKLSQLTSLLSSIEDKVKALLHEGPEPPHWRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDSSDDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTSNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAEAIIHKIRQQQ-YADLLAHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPVYTPLT
HIGEMTGHFQGAIKLQTSQGKKREKLYDFVKTERDE-PSGPKCLKSLTSHDSMKQWEPAA
RAP-LC-----------------------------------SAPSITDIVNPSYIGVGPF
GQPLHP--KLALSPTLDQPFPAWSYDPLPKDSSLGLGRGDSPPTPPSQPPLSPKKLASAM
ANRGPCPRAQE-PRPSELGKGAAEA-LQEDLP--LTKPEMFENPLYGSVSTFPKLVPRKE
QESPKMLRKEPPPCPEPTAMLPSVLLPKAPEAEGSKGIAKQA----STPFLSPAPRLRSF
TCSASP---EPRAAGGDR-SQGKPKGPAGSQ-AP------VAAKRPIKPSRSEVSQQ---
--STPTPALRPPLPVKSPAVLQLQHAKGRDYRDNSEFPHHGKHRPEEGL---LGRTTMQQ
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMKFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESIVSPPELPPRN-IPPSAG
---SCEAKEVPLSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYA--------YTKQ
KATGCQRAQWKC-------LMSWGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAISSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNSELPYHGKHRPEEGPPGPLSRTAMQV
RGATRGLVCMCARVHA--------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MECSLAKAKPR----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAISSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNSELPYHGKHRPEEGPPGPLSRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MGPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGRDG
SFLVRASESITRAYALCVLYRNCVYTYRILPNEEDKFTVQASEGVPVRYFTKLDQLIEFY
RKENMGLVTHLQYPVPLEEEDAGDDPEEDT----------ESVMSPPELPPRN-ILFSVG
---NCETKELPVPAENPRAPEASRPSLSETLLQRLQNMDTSGLPEEHLKAIQEYLSTQLA
LDSDFVKTGSSSLPHLKKLTSQLCKELHG----EVVRTLPSLESLQRLFDQQLSPGLRPR
AQVPCEASSVSMVAKLSQLTSLLFSIEDKVKALLHEGPEPPHWRSVIPPVTFEV--KAES
LGIPPKMQLKVDVESGKLIIKKSKDSSDDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAEAIVQKIRQQQ-YADLLAHDQLLTERREQKVFLNFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HIGEMTGHFRGAIKLQTSQGKKREKLYDFVKTERDE-SSGPKCLKSLTSHDSMKQWEPAG
RAP-LC-----------------------------------GSLSITDIVNPSYIGLGPF
GQPLHP--KPAMSPSPDQPFPAWSYDPLPKDSSLGPGRGDSPPTPPSQPPLSPKKFASTI
ANRGPCPRAQE-PRPSELGKGAAGA-LQEDLP--PAKPEMFENPLYGSVSTFPKLAPRKE
QESPKTPRKEALPCLEPAAT----------------------------------------
------------------------------------------------------SQP---
--PTPTPAPRPPLPAKSAAVLQLQHARGRDYRDNSELPHHGKHRPEEGL---LSRTAMQV
SPAR----V--HV-----------CV------CESVYPYTSYE---------------EK
LEGGRI------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT---------VESVVSPPELPPRN-IPLTAS
---SCEAKEVPLSNESPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
QDSEFVKTGSSSLPHLKKLTTLLCKELYG----NASAALTIIEWCMAVSDL--PPDW---
--MWGD---------------------GKMNLGGHEASEWSHQPWRSGGCIWGI--MGDA
YGESLKAGG--KVTAGESVARS------------------HS-LTTLDACFQVAVLEVHT
DLRSSLTKSFAKCNVQKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPTKQWEATS
RAP-PC-----------------------------------SGSSITEIINPNYMGVGPF
GSPMPL--HVKQTLSPDQQPTAWSYDQLPKDSPLGPCRGESPPTPPSQPPISPKKFLPST
ANRGLPPRTQE-LRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSLSSFPKPAPRKD
QESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQV----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTPVSSQ-AP------VPAKRPIKPSRSEINQQTP-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPVGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDTGDDPEEDTGWQEVLLGTLESVLSPPELPPRN-IPLSAG
---SCEAKEAPLSNENPRATEASRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLV
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
LQAPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KSES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKVS-------------------------------DSNALPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAETIIQKIKQQH-YADLLCHDQLLTERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERCTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTTDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELLV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFQGEIKLQTSQGKKREKLYDFVKTERDE-ASGPKSLKSLTSHDPMKQWEPTN
RAP-PC-----------------------------------SGSSITEIINPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGSCRGEGPPTPPCQPPISPKKFSSST
ANRGLCPRTQD-SRPSDLGKNAGDGLPQEDLL--LTKPEMFENPLYGSVSAFPKPAPRKD
QESPKMLRKEPPPCPEPGLLSPSIVLTKVQETERSEGPAKQA----------PAPRLRSF
TCSSS---TEGRAASGDK-SQGKPKTPANSQ-AP------VPAKRPIKPSRSEMNQQTL-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQV
RCATRGLVCMYVRVHA--------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVSS

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDRFTVQASEGVPVRYFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAGDDPEEDT----------ESVASPPELPPRN-IPLSTG
---PCETKELLGPAENPRAPEASRPSLSETLFQRLQTMDTSGLPEEHLRAIQEYLGTQLA
LDSEFAKTGSSSLPSLKKLISQLCKELHG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPCEASPVTMVAKLSQLTSLLSSIEDKVKALLHEGPESPHWRSLIPPVTFEV--KAES
LGIPQKLQLKVDVESGKLIIKKSKDGSDDKFYSH---KKILQ-LIKSQKFLNKLMILVET
EKEKTLRKEYIFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLR-EVT--
SMNFKPIAVHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDRKLSSFNITHRFTHLFWLGDLN
YRVDLPTWEAEAIIQKIRQQQ-YADLLAHDQLLTERKEQRVFLHFGESLFAPLPLPCPLR
VLAGGGPGPAEQRNSGVNTKIPISVSEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---GDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGAIKLQTSQGKKREKLYDFVKTERDE-PSGPKCPKSLTIQDPVKQWEPA-
----GR-----------------------------------ASFGLTDIMNPSYI---PV
RQPVTA--KLPMSPLPDQPLPAWSYDPQPKDPSLGPGRGDSPPTPPSQPPLSPKKFTSAS
ANRGPCPRVQE-SRPSEQGKGSTEA-PQEDLL--LSKPEMFENPLYGSVSAFPKLVPRKE
QESPKMLRKEPTPCPEPSI-----SFSKAPEAEGSKGPGKQA----PTTFLSPTPRLRSF
TCSAST---EGKATSGDR-GQGKPKGPASSQ-AP------VPAKRPIKPSRSEVSQQ---
--STPTPAPRPPLPVKSPAVLQLQHAKSRDYRDNSELPHHGKHRPEEGL---LGRTAMQQ
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESVVSPPELPPRN-IPLSAG
---SCEAKEVPLSNENPRVTETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGETNPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFRGEIKLQTSQGKTREKLYDVTPC-------------------------LPC
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAISSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNTELPHHGKHRPEEGPPGPLSRTAMQV
RGATRGLVCVCVRVHALVRMCVPMHVGVHACVCACMCARMHVHTCE--------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT---------VESVVSPPELPPRN-IPLTAS
---SCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
QDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVIRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEVTS
RAP-PC-----------------------------------SGSSITEIINPNYMGVGPF
GPPMPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSLSSFPKPAPRKD
QESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQV----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTPVSSQ-AP------VPAKRPIKPSRSEINQQTP-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MTSFSWRE

PF03372 // ENSGT00760000119075_8_Domain_2 (817, 941)

RIKKVFLNF---------------
--------------------------EEEEITFAPTYRFERLTREKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GQ
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MVAKLSQLTSLLSSIEDKVKALLHEGPESPNRRSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIRQQQ-YSDLLAHDQLLLERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALHLETTETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-ASGMKCLKNLTSHDPVKQWEPAG
RVP-AC-----------------------------------GVSSLNEIINPNYIGVGPF
GQPLHG--KS--SLSPDQQLTAWSYDQPPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGLCPRMQE-TRSGDLGK--VEALLQEDLQ--LTKPEMFENPLYGSVSSFPKVVPRKE
QESPKMLRKEPPPCPDPGISSPSILLPKVQEVEGVKGSSKQV----PVPVFGPTPRMRSF
TCSSSA---EGKMPSGDK-NQGKPKTSASTQ-AP------VPAKRPIKPSRSEMSQQ---
--MTPIPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHGKHRHEEGL---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAMDEAEEDT----------ESVMSPPELPPRN-IPVSAG
---PCEAKDPPLPIENPRAPEVTRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLNTQLV
LDSDFVKTGSSNLPHLKKLTSLLCKELHG----EVIRTLPSLESLQRLFDQQLSPGLRPR
PQVPSEANPINMVAKLSQLTSLLSSIEDKVKALLHEGSESPNRCSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIIKKSKDGSEDKFYSHKKSKPFS----------MCL------
-----------PFLLQKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWVRRTRLGQSCTEQRLPRLHSPD------------------------------
---------------------------------------------SEMQVSYFLSCMKYN
LPSWCDRVLWKSYPLVHVVCQSYGEWSIGG------MFKIILD----DLVSLRKTVFHGP
RK---A----TLKSLFCLVL-------ALWSAKPASDSPTGFVKSQEGENEEGSEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALHLETTETQLPIYTPLT
HHGEMTGHFRGEIKLQTDE------------------SSGVKCLKNLTSHDPMRQWEPAG
RVP---------------------------------------ACGVNEIINPNYIGVGPF
GQPL----HGKSTLSPDQQLTAWSYDQPPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGPCSRVQE-ARPSDLGKA--EALLQECLQ--LTKPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPPPCPDPGISPPSILLPKAQDVEGIKGTSKQV----PVPVFGPTPRMRSF
TCSSSA---EGRIPGGDK-NQGKPKTSAGSQ-AP------VPVKRPIKPSRSEMSQQTT-
----PIPAPRPPLPVKSPAVLQLQHSKGRDYRDNSELPHHGKHRHEEGL---LGRTAMQV
RRAV----CVCVCVC------------VCVCVCVCVCVNLGFEPGTSVP-----------
------------------------------LIGPTQHLQMILEREGGELWINI-------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDAGDDPEEDT----------ESVTSPPELPPRN-IPLTAG
---PCEAKEVPLSTENPRATEVSRPSLSETLLQRLQSMDTSGLPEEHLKAIQEYLSTQLT
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQAPGEANPINMVSKLSQLTSHLSSIEDKIKTLLHEGPESSHRRSLIPPVTFEV--KSES
LGIPQKVQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YADLLAHDQLLTERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKKREKLYDFVKTERDE-SSGPKSLKSLTSHDPMKQWEPAS
RAP-PC-----------------------------------GGSSITEIINPNYMGVGSF
GQPVAL--HMKQNLSPDQQPTAWSYDPLPKDSSLGPGRGESPPTPPCQPPISPKKFSSST
ANRGPCPRTQE-PRPTDPGKNAGEALPPEDLP--LTKPEMFENPLYGSVSSFPKVAPRKE
QESPKLLRKEPPPCPEPGGPSPSIVLTRAQEAERSEGTT--K----------PAPRLRAF
TCSIS---AEGRAAGADK-GQGKSKAAAGCQ-AP------VPVKRPIKPSRSEMSQQML-
----PAPTPRPPLPVKSQAVLHLQHSKGRDYREHTELPHHGKHRPEEGP---LSRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------VLQ-LIKSQKVPNKLVIVLET
EKEKTQRKEYVFSDSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 784)

IFIGTWNMGAAPPPKKIS
S---WFLSK--GQGKTRDDTADYIPHDIYVIGTQEDPQGEKEWLETL--RQSLQ-EIT--
SISFKVIAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSFGFVNSHLTSGSEKKQRRNQNYTNILRFLTLGDKKLSPFNITHRFTHLFWLGDLN
YRVE--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------AAAMDQC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WYHGNITRSKAEDLLSKVGKDG
SFLVRASESIASAYALCVLFRNCVYTYRILPDKEKKLIVQASEGVPVKYFDNLEELIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVWHLKYPVPREEEEAADEPEEDAA---------DQVPTPPILPPRN-ILMALP
G---SETKDVSSLPENSRVADVNKLSLSETLLQRLQYQDTSSVSDEHLKLIQDYLRVHII
SDLEMVQTGSSNLPQLKKLLALLCKGLFS----EASRTLPSLESIQKVFEQQLHPGIHQR
SQMLGEASPVNIVLKLNQLISLLSSIEEKVKTLLIEGPDSTHRRSLIPPVTFEV--KADS
LGIFSKIHLKVDVEMGKLIIKRAKDGPEDKFYTH---KKILQ-LIKSQKVPNKLVIVLET
EKEKTQRKEYVFSDSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

VFIGTWNMGAAPPPKKIT
S---WFLSK--GQGKTRDDTADYIPHDIYVIGTQEDPQGEKEWLETL--RQSLQ-EIT--
SISFKVIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSFGFVNSHLTSGSEKKHRRNQNYTSILRFLTLGDKKLSPFNITHRFTHLFWLGDLN
YRVEQPPTEAENIIQKIRQQQ-YPELLAFDQLLIERKDHKVFLQFE--------------
---------------------------EEEITFAPTYRFERGTREKYAYTKQKATGMKYN
LPSWCDRVLWKSYPMVHVVCQSYGCTTDITTSDHSPVFATFEVGVTSQFVSKN-----DS
KY---MNTQGEIEFLHCFATLKTKSQTKFYIEFHSSCLES-FVKSQEGENEDGSEGELVV
KFVDALPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRIEATESLVPIHTVLT
HHGEKTGVFQGEIKLQTSQGKQREKLYDFVKIERDE-IAGQKPKN-TNNLELNKDSDQLS
S----------------------------------------SCT-PTDISNPNYLGMAAF
PQQPFAASQLKQAPSPDQPSSLWNYEQQPKDSSSVMGQRESSSTSPSLSPLSPKPPLQTP
VNRSICNRSQ-EHLPPDLGKNMAEPL-LQEEG--QQKPEMFENPLYGYTASKGKAAPKKE
QDYPKASRKEQLPLPEQSFHLTKSQEPEGSKSSS-K----QP----SPPFLVPTQRFRSY
TCSSQS---EKEYGA--KKTQGKPKAAASSEN-S------ALLKKSVKPLRSEVSP-GVQ
GQ-----------------LMDMQSSKGRDYRDSSELPHAGKHRIEEGP---LRQDSHT-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------VAAMVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDAGDEPEEETG----------RRLSPPELPPRN-IPLSAG
---PCEAKEVPLSSENLRATEVSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSDFVKTGSSSLPHLKKLTILLCKELYG----EVLRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVAKLSQLTSVLSSIEDKVKALLHEGTESPHRRSLIPPVTFEV--KSES
LGIPQKLQLKVDVEAGKLIIKKSKDGSEDKFYTH---NKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIVQKIKQQQ-YADLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCFATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGPKSLKSLTSHDPMKQWEPT-
NRVPPG-----------------------------------SGSSINEIINPNYMGVVPF
GH-------MKQSLSPDQQPTAWSYDQPLKDSSLGPGRGESPPTPPSQPPVSPKKFSSST
AARGPCPRTQE-SRPCDLGKNSTEPSPQEDAQ--LTKPEMFENPLYGSVSSFPKLLPRKE
QESPKMLRKEPLPCPDPGILSPSILLPKAQEAEGTKGTGKPA----PTPFLSPTPRLRSF
TCSSS---AESRPVAGDK-SQGKAKAPASLQ-A------QVPAKRPIKPSRSELS-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDTGRQEVLLRTLESVLSPPELPPRN-IPLSAG
---PCEAKETPLSNENSRATEASRPSLSEMTFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTVLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
LQAPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KSES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNALPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLCHDQLLTERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERCTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTTDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLEN-FVKSQEGENEEGSEGELLV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFQGEIKLQTSQGKKREKLYDFVKTERDE-ASGPKSLKSLTSHDPMKQWEPTS
RAP-PC-----------------------------------SGSSLTEIINPSYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGSCRGEGPPTPPCQPPISPKKFSSST
ANRGLCPRTQE-SRPSDLGKNTGDGLPQEDLP--LTKPEMFENPLYGSVSSFPKPVPRKD
QESPKMLRKEPPPCPEPGLLSPSIVLTKVQEAERSEGPAKQA----------PAPRLRSF
TCSSS---TEGKAASGDK-SQGKPKTPANSQ-AP------VPAKRPIKPSRSEMNQQTL-
----PTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQV
RCTTQGLVCTCVRVHA--------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISKAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDAGDEPEEDTE----------GVLSPPELPPRN-IPLPAG
---PCEAKEAPASSENPRATEVSWSSLSELLFQRLQSIDTSGLPEEHLKAIQDYLTTQLA
LDSDFVKTGSNSLPHLKKLTMFLCKELYG----EITRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPVNMVAKLSQLTSLLSSIEDKVKALLHEGTESPHRRSLIPPVTFEV--KSES
LGIPQKLQLKVDVESGKLIIKKSKDGSEDKFYSH---NKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQAEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EIT--
SMNFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAETIVQKIKQQQ-YTDLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCFATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETLLPIYTPLT
HHGEMTGHFRGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKSLKSLTSHDPMKQWEPAA
NRVPPC-----------------------------------SGSSITEIINPNYMGVVPF
GH-------MKQSLSPDQQPTAWSYDQPLKDSSLGPGRGESPPTPPSQAPISPKKFSSST
TTRGPCPRTQE-SRPCDMGKNSAEPSPQEDPQ--LTKPEMFENPLYGSVSSFPKLLPRKE
QESPKMLRKEPPPCPDPGMLSPSILLPKAQEAEGTKGTGKPA----PAPFLSPTPRLRSF
TCSSS---AESRPAGGDK-SQGKAKAPASSQ-A------PVPAKRPIKPSRSELSQQTP-
--PAP--AQRPPLPVKSPAVLHLQHSKGRDYRENAELPHHGKHRPEDAP---LGRAAMQV
RGEG-------ACTH--------ARE------TGR-RAWGRAQGGSGGVGVSPAPPRPLC
ACGRAQGGLCMPVVRQKAPVQISEFEPRPPVPAPTL------KGLNKALGTNSLSPPVSD
LQELRLHKHKDPGSFIFHCHHH

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MPAMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDAIDEAEEDT--V-------ESVMSPPELPPRN-IPMSAG
---PSEVKDLPLATENPRAPEVTRLSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLL
LDSDFLKTGSSNLPHLKKLTSLLCKELHG----EVIRALPSLESLQRLFDQQLSPGLRPR
PQVPGEASPITMVAKLSQLTSLLSSIEDKVKALLHEGSESTTRRSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YSDLLAHDQLLLERKDQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLETTEAQHPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGMKCLKNLTSHDPMRQWEPAG
RVP-AC-----------------------------------GVSSLNEIINPNYIGMGPF
GQPLHG--KS--TLSPDQQLTAWSYDQLPKESSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGPCPRVQE-ARPGDLGK--VEALLQEDLL--LTKPEMFENPLYGSMSSFPKPVPRKE
QESPKMLRKEPPPCPDPGISSPSIVLPKAQEVESVKGTSKQA----PVPVLGPTPRIRSF
TCSSSA---EGRMTSGDK-SQGKPKATASSQ-AP------VPVKRPVKPSRSEMSQQ---
--TMPIPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHGKHRQEEGL---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------PTMVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDTGDEPEEETV---------DCVESPPELPPRN-IPLSAG
---PLEAKEVPTACDSSRVPEVSKPTLSETLLQRLQSIDTSGLPDEYLKAIQDYLSTQLV
LDAEFMKTGSSSLPHLKKLTMLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVSGEASPINMVAKLSQLTSLLSSIEDKVKALLHEGHECPHRRTLIPPVTFEV--KSES
LGIPQKVQLKVDVESGKLIIKKSKDGPEDKFYNH---KKILQ-LVKSQKFLNKLVIVVET
EKEKTVRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTVWPSHLWNIRIVVLAKPEHE---NRFSHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRLELPVSEADTIIQKIKQQQ-YADLLAHDQLLLERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDRYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLSCFATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELLV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCVALRLEAKETQFPIYTPLT
HHGEMTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-VIGPKGLKSFTSHDPMKLWEPAN
RAP-LC-----------------------------------SGPSITEIINPNYMGVGPF
GPPMSL--HGKQAISPEQQPAAWNYDPLPKDASLGPGKGESPPTPPSQQPVSPKKFSSSP
AGWGPCLRTQE-SRPSDLGKNMAEPPLQENLQ--LKKPEMFENPLYGSVSSFPKPVPRKE
QESPKMLRKEPPPCPDPGISSPAILLTKAQEADSSKGTSKQ----------VPTPRLRSF
TCTSST--TEGGAAAGGEKNQGKPKPAASSL-AP------VPAKRPVKPSRSEISQQIPP
AP----TQQRPPLPVKSPAVLQLQHSKGRDYRDSAELPHQGKHRPEEGP---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MPAMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQFPVPLEEEDAIDEPEED---T-------ESVMSPPELPPRN-IPVSAG
---PCEAKDLPLPTENPRAPEVTRLSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLM
LDSDFLKTGSSNLPHLKKLTSLLCKELHG----EVIRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPITMVAKLSQLTSLLSSIEDKVKALLHEGSESTNRRSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIIKKSRDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFSDSKKREGFCQLLQQMKNKHSEQSEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YSDLLAHDQLLLERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GA---VDSQGQIEFLACYATLKTKSQTKFYLELHSSCLES-FVKSQEGENEEGDEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLETTESQLPIYTPLT
HHGEMTGHFRGEIKLQTSEGKMREKLYDFVKTERDE-SSGMKCLKNLTSHDPMRQWEPAG
RVP-AC-----------------------------------GISSLNEIINPNYIGMGPF
GQPLHG--KS--TLSPDQQLTAWSYDQLPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGSCPRVQE-TRPGDLGK--VEALPQEDLP--LTKPEMFENPLYGSVSPFPKLVPRKE
QESPKMMRKEPPPCPDPGVSSPSIMLPKAQEVENVKGTSKQA----PVPVFGPTPRIRSF
TCSSSA---EGRMPSGDK-SQGKPKAPASSQ-AP------VPVKRPVKPSRSEMSQQ---
--TTPIPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHGKHRQEESL---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVSG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRAKAEELLSRAGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPSE-DKFTVQASEGVPVRYFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDAEEDM----------ESVTSPPELPPRN-IPLSVG
---PCETKELPVPAENARAPEASRPTLSETLFQRLQSMDTSGLPEEHLRAIQEYLSTQLA
LDSELVKTGTSSLPHLKKLISQLCKELHG----EVVRTLPSLESLQSLFDQQLSPGLRPR
SQVPCEANPVNMVAKLSQLTSLLSSIEDKVKALLHEGPESPHWRSLIPPVTFEV--KAES
LGIPQKMQLKVDVEAGKLIIKKSKDGSDDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDTLGEKEWLEIL--RNSLR-EVT--
SMTFKPVAIHTLWNIRIVVLAKPEHE---NRISHICTSNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDRKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAEAIIQKIRQQQ-YTDLLAHDQLLMERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFELGVTSQFVSKN-----SP
GT---GDSQGQIEFLACCATLKTKSKTKFYLELHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRMEATETGVPIYTPLT
HHGEMTGHFQGAIKLQTSQGKTREKLYDFVKTERDE-PSGLKCMKSLTSQDPMKQWEPAY
RAA-PC-----------------------------------GTLGLNDIANPNYI---PF
GQPVRV--KLTMSPSLDQPLPAWSYDPLPKDSSLGPVRGDSPPTPPSQPPLSPKKFSSAP
ANRGSCPRAQE-SRPSEPGKGTTEA-PPEDPS--LCKPEMFENPLYGSVSAFPKVVPRKE
QESPKILRKEPPPCPEPGALVPSSLLSKPQEAEGSKGTSKLA----PTPFLSPVPRLRSF
TCSASS---EGRATSGDR-CQGKPKAPAVSQ-AP------VPSKRPIKPSRSEVSQQ---
--PTPTPAPRPPLPAKSPAVLQLQYAKSRDYRDNSELPHHSKHRPEDGL---LGRTAMQV
SSAP----M--HV-----------ST------SVRVRTFVPAL------------LTQHC
LCSDG-------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MSTMVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPVKFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ENIVSPPELPPRN-IPLSAA
---PCEAKELPPPIENPRAPEVSRPSLSETLLQRLQNMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPCEASPINMVSKLSQLTCLLSSIEDKVKALLHEGPESSHRRSLIPPVTFEV--KSES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNRHSEQPEPDMITIFV

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KQSLQ-EIT--
SMTFKTVAIHTLWNIRMVVLAKPEHE---NRISHICTDTVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVDLPTWEAEAIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDRYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GA---VDGQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIHTPLT
HHGEMTGHFRGEIKLQTSQGKKRERLYDFVKTERDE-SSGQKSLRSLTSHDPMKQWEPAG
RAP-PC-----------------------------------GGSGILEIMNPNYMGVGPF
GQPTSL--HVKQTLSPDQQPTAWSYDQPPKDSSLGPGRGDNPPTPPCQPPLSPKKFSSST
ANRGPCLRTQE-SRPGDPGKSG---TEPEDLP--LTKPEMFENPLYGSVSAFPKPAPRKE
QESPKMLRKEPPPCPEPGLLSPSITLTKAQEAERSEGTGKQV----------PAPRLRSF
TCSSS---AEGRAATGDK-SQGKPKAPAGPQ-AP------VPAKRPIKPSRSEMSQQ---
-------TPRPPLPVKSLAVLHLQH-QGRDYRDNSELPHHGKHQTEEGP---LSRTATQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMKFFTTLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDAGDDPEEDTGV--------ESIMSPPELPPRN-IPLSAG
---ACEAKDASPSIDNPRAPEISRPSLAETLLQRLQNLDTSGLPEEHLKAIQDYLSTQLT
LDSEFVKTGSSNLPHLKKLTTQLCRELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPCEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPDSSHRRSLIPPITFEV--KSES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
DKEKTLRKEYVFADSKKREGFCQLLQQMKNRHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SITFKTLKVHAHWSLSLLLSRPQPDL---NPPAPMYVAGVLTILLLPLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTTDIMTSDHSPVFATFEAGVTSQFVSKN---DTGP
GT---TDSQGQIEFLRCNATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFEETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETPLPIYTLLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSAPKSLKSLTSHDPMKQWEPAG
RVP-LC-----------------------------------SGSSITEIINPNYMGVGPF
GQPMPM----KQTLSPDQQPTPWSYDQPPKDSSLGLGKGESPPTPPCQPPLSPKKFSSST
ANRGPCLRTQE-SRPGDLGKGA---EALEDLP--LSKPEMFENPLYGSVSSFPKPAPRKE
QESPKTLRKEPPPCPEPGILTPGITLIKAQEADRSEGTGKQV----------PAPRLRSF
TCSSSA--AEGRAAAGDK-SQGKPKASASSL-AP------VPAKRPIKPSRSDMSPQTL-
----PAPSPRPPLPSKSPAVLHLQHSKGRDYRDSSELPHHGKHRPEEGS---LSRTAAQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MPAMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIDF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDAIDEAEEDT--V-------ESVMSPPELPPRN-IPMSAG
---PSEAKDLPLATENPRAPEVTRLSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLL
LDSDFLKTGSSNLPHLKKLMSLLCKELHG----EVIRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEASPITMVAKLSQLTSLLSSIEDKVKSLLHEGSESTNRRSLIPPVTFEV--KSES
LGIPQKMHLKVDVESGKLIVKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLELL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAEAIIQKIKQQQ-YSDLLAHDQLLLERKDQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLETTEAQHPIYTPLT
HHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDE-SSGMKCLKNLTSHDPMRQWEPSG
RVP-AC-----------------------------------GVSSLNEMINPNYIGMGPF
GQPLHG--KS--TLSPDQQLTAWSYDQLPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSST
ANRGPCPRVQE-ARPGDLGK--VEALLQEDLL--LTKPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPPPCPDPGISSPSIVLPKAQEVESVKGTSKQA----PVPVLGPTPRIRSF
TCSSSA---EGRMTSGDK-SQGKPKASASSQ-AP------VPVKRPVKPSRSEMSQQ---
--TTPIPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHGKHRQEEGL---LGRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDACDEPEEETE----------GVLSPPELPPRN-IPLSAS
---PCETKEAPLPSEHLRAAEVSRPSLSETLLQRLQSMDTSGLPEEHLKAIQDYVSTQLT
LDSDFAKSGSSSLPHLKKLTALLCKELYG----EVNRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINTVAKLSQLTSLLSSIEDKVKALLHEGPEASHRRSLIPPVTFEV--KSES
LGIPQKLQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFPNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKEIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSSFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YADLLSHDQLLMERKDQKVFLHFE--------------
---------------------------EEEITFAPTYRFERMTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMMGHFRGEIKLQTSQGKTREKLYDFVKTERDE-STGPKSLKSFTSHDPMKQWEPT-
NRVPPC-----------------------------------GGSSITEIINPNYMGVGPF
GH-------MKQTLSPDQQPTAWSYDQPLKDASLGAGRGDSPPTPPSQPPVSPKKFSAST
ASRGPGPRTQE-SRPGDAGKSAGDALPAEDLQ--MTKPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPPPCPDPGILSPNIPLSKAQEAEGSKGTGKPAPAPAPPPFLSPTPRLRSF
TCSSSAATAEGRPAGGDK-SQGKPKAPAGPQ-APAPVPVPVPAKRPIKPSRSDLSQPLP-
--PTP--AQRPPLPVKSPAVLHLQHSKGRDYRDNAELPHHAKHRPEDAP---VSRAAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------ATMVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYRNCVYTYRILPNEEDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDAGDEPEEDAE----------SIQSPPELPPRN-IPLSAG
---PCEAKEVPLLSDNLRATEVSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSDFVKTGSSNLPHLKKLTMLLCKELYG----EVIRTLPSLESLQRVFDQQLSPGLRPR
PQVPGEANLVNMVAKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KSES
LGIPQKLQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
SMTFKTIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIRQQQ-YADLLSHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGDTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLELHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETLLPIHTPLT
HHGEMMGHFRGQIKLQTSQGKMREKLYDFVKTERDELSSGPKSLKSLTSHDPMKQWEPT-
NRIPPC-----------------------------------GGSSITEIINPGYIGAAPF
GH-------MKQTLSPDQQPTAWSYDQPLKDSSLGPGRGESPPTPPSQPPISPKKFSSST
TSRIPGPRTQE-SRPSDVGKNMAEPLPQEDPP--LTKPEMFENPLYGSVSSFPKLVPRKE
QESPKMPRKEPPPCPDPGISSPSILLSKAQETEGNKGTGKPVPP--PAPFLSPTPRLRSF
TCSSS---ADGRPAGGDK-SQGKPKAPTGTQ-V------PVPAKRPIKPSRSELSQ----
--------QRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKPRPEDPP---LARAAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------MPAMVPG

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
RKENMGLVTHLQYPVPLEEEDTVDEAEEDT----------ENVMSPPELPPRN-IPVSAG
---PCEAKDLLLQTENLRAPEVSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLV
LDADFVKTGSSNLPHLKKLTSLLCRELHG----EVVRTLLSLESLQRLFDQQLSPGLRPR
PQVPGEPNPINMVAKLSQLTSLLSSIEDKVKALLHEGSESPHRRSLIPPVTFEV--KSES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEML--RHSLQ-EVT--
RMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPAWEAEAIIQKIKQQQ-YVDLLAHDQLLMERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGREGELVV
RFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGEMTGHFQGEIKLQTSQGKKREKLYDFVKTERDE-SSGMKCMKTLTSHDPMRQWEPAG
RVPAAC-----------------------------------GAPSLTEIINPNYMGMGPF
GQPLHG--KP--SLSPDQQLTTWSYDQLPKDSSLGPGRGEGPLTPPSQPPLSPKKFSSST
ANRGPCPRAQE-ARPGDLGKNPAEALLQEDLQ--LTKPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPPPCPDLGISSPSVLLPKAPEAESSKGTGKQA----PMPVIGPTPRVRSF
TCSSPA---EGRTTSGDK-SQGKPKTSASAQ-AP------VPAKRPIKPSRSEMSQQ---
--TTPTPAPRPPLPVKSPAVLQLQHSKGRDYRDNTELPHHSKHRPEESL---LSRTAMQV
CWGT----C--VCV------------------CVYVH----VTGPGEACAVTKGYTWPLS
PVSVTGPIL--PLQ----------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 586)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESLVSPPELPPRN-IPLSAG
---SCEAKEVPLSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKTQLKVDVESGKLIVKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFI

PF03372 // ENSGT00760000119075_8_Domain_1 (586, 934)

GTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFRGEIKLQTSQGKTREKLYDFVKTERDE-SSGQKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAVSSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNTELPHHGKHRPEEGPPGPLSRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVHC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSKTGKDG
SFLVRASESIPRAYALCVLYRTCVYTYRILPNEEDKFTVQASEGVPVRFFTSLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPIEEEEAGDELEEE-T---------EFFLSPPELPPRN-LPLSSG
A---SEAKEV-LPPDNSRVMEPSKLSLSETLLQRFQGMDTSGLPEEHLKAIQDYLSTQVS
LDTDFVKTGANNLPHFKKLIMVLCKELYS----EVTRTLPTLEALQRLFDQQLSPGIRSR
PQACAEASPVNIMAKLGQLTSLLSSLEDKGKAFLGGGPESTHRRSLIPPVTFEV--KSES
LGIPQKMQLKVDVESGKLIIKKSKDGPEDKFYSH---KKILQ-LIKSQKFHNKLVIVVET
EKEKTLRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGDAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--KHSLQ-EIT--
DITFKMVAIHTLWNIRIVVLAKLEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRLELPPSEAENIIQKIKQQQ-YPELLLHDQLLTERKEQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTREKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGCTSDIMTSDHSPVFATFEVGVTSQFVSKN-----GP
GN---VDSQGQIEFLNCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGTEGELVV
KFADDLPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRSEAIESLVPIYTALT
HHGEMMGHFRGEIKLQTSQGKKRERLYDFVKIERDE-ASGQKSLKSLISHDPIKQWECSS
RLT---------------------------------------------------------
------------------------------------------------------------
----------------DLGKNMAEPSPMDEQL--LAKPEMFENPLYGAVSVFPKPAPRKE
QESPQTLRKDRPGCPDPGTPSPAVIFTKPPEGEG-KLASRQT----S-APLLPVPRMRSF
TCSSST---EGRTTLSGEKTQGKPKPSTPSEN-P------VPAKRPVKPVRSEMSQQGNP
AQ-----TSRPPLPAKSPAVLHLQHSKARDYRESSELPHHGKHWPEEGP---TSRTSMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPT

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRAGKDG
SFLVRASESIPRAFALCVLYRNCVYTYRILPNEDDKFTVQASEGVPMRLFTKLDQLIEFY
RKENMGLVTHLQYPVPLEEEDAVDDPEED-T---------ESVMSPPELPPRN-IPL---
-SGPCEAKELPPAAENPRAAEVSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLT
LDSDFVKTGSSSLPHLKKLTSLLCKELYG----EVVRTLPSLESLQKLFDQQLSPGLRSR
PQVPGEANPINMVAKLSQLTSLLSSIEDKVKALLHEGPEYTHRRSLIPPVTFEV--KSES
LGISQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEIL--RHSLQ-EVT--
SMTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLN
YRVELPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLQCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELLV
RFGDTLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIHTPLT
HHGEMTGHFQGQIKLQTSQGKKREKLYDFVKTERDE-SSGPKGSKSLTSHELVKQWEPAS
RTP-LC-----------------------------------SSSGATELINPNYMV-GPF
GQSL----HMKQTLSPDQQLTAWSYDQPPKDSSLGSGRGESPPTPPSQPPLSPKKFSPSI
APRGPCLRAQD-CWPSDLGKIPPEAP-----P--PDEPEMFENPLYGSVSSFPKLVPRKE
QESPKMLRKEPAACLDPGVSSPSILLTKAQEAEGGKGTGKQG----PPSFLSPAPRLRSF
TYSSSA---EGRA-AGGDKSQGKPKAPPSSQ-AP------VPAKRPIKPSRSEMSQQTAP
TP-----APRPPLPIKSPAVLQLQQSRGQDYRDNSELPHHGKHRPEEGL---ISRTAMQV
CSWTRL--CLCVHTC------------------AYTCVHDHS----RSCSMRKS------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESVVSPPELPPRN-IPLSAG
---SCEAKEVPLSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFLHFE--------------
---------------------------EEEITFAPTYRFERLTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSISEILNPNYMGVGPF
GPSVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCPPPISPKKLLPSA
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---ADGRAAGGDK-SQGKPKTAISSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNTELPHHGKHRPEEGPPGPLSRTAMQ-
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MVPC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WNHGNITRSKAEELLSRTGKDG
SFLVRASESISRAYALCVLYQNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFY
KKENMGLVTHLQYPVPLEEEDTGDDPEEDT----------ESIVSPPELPPRN-IPPSAG
---SCEAKEVPLSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLA
LDSEFVKTGSSSLPHLKKLTTLLCKELYG----EVVRTLPSLESLQRLFDQQLSPGLRPR
PQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRRSLIPPVTFEV--KAES
LGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSH---KKILQ-LIKSQKFLNKLVILVET
EKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEIL--KHSLQ-EIT--
SVTFKTVAIHTLWNIRIVVLAKPEHE---NRISHICTNNVKTGIANTLGNKGAVGV-SFM
FNGTSLGFVNSHLTSGSEKKLRRNQNYMSILRFLALGDKKLSPFNITHRFTHLFWFGDLN
YRVDLPTWEAETIIQKIKQQQ-YADLLSHDQLLTERREQKVFL-----------------
-----------------------------------------LTRDKYAYTKQKATGMKYN
LPSWCDRVLWKSYPLVHVVCQSYGESKHWGKQ------TTIREGSLGQ--LLG-----GP
GT---VDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLES-FVKSQEGENEEGSEGELVV
KFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLT
HHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDE-SSGPKTLKSLTSHDPMKQWEATS
RAP-PC-----------------------------------SGSSITEILNPNYMGVGPF
GPPVPL--HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPTTPPCQPPISPKKFLPST
ANRGLPPRTQE-SRPSDLGKNAGDTLPQEDLP--LTKPEMFENPLYGSVSSFPKPAPRKD
QESPKMLRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQA----------PAPRLRSF
TCSSS---AEGRAAGGDK-SQGKPKTAISSQ-AP------VPVKRPIKPSRSEMNQQTQ-
----PTPTPRPPLPVKSPAVLHLQHSKSRDYRDNSELPHHGKHRPEEGPPGPLSRTAMQV
RGATRGLVCMCARVHA--------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MDQC

PF00017 // ENSGT00760000119075_8_Domain_0 (159, 240)

WYHGNITRAKAEDLLSKVGKDG
GFLVRASESIPSAYALCLLFHNCVYTYRILPSKDNKLIVQASEGVPVKHFDNLDELIEF

ENSGT00760000119075_8_Linker_0_1 (240, 583)

Y
KKENMGLVWHLKYPVQQEEEEAGDEAEED-V---------DPVPTPPVLPPRP-PLPALL
T---CETKEASPPNDNCKVADINKLSLSETLLQRLQNQDTSSVSEEHLKIIQDYLRVHIT
SDIEIVQTGSGNLPQLKKLLTTLCKGLFS----EASRALPSLESLQKVFDQQLPPGIHQR
PQLLGEASPANVVQKLNQLIFLLSSVEEKVKTLLIEGPDSTHRRSLIPPVTFEV--KADS
LGISSKIQFKVDVETGKLIIKKSKDGPEDKFYTH---NKILQ-LIKSQKFPNKLVIVLET
EKEKMQRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMIT

PF03372 // ENSGT00760000119075_8_Domain_1 (583, 941)

IFIGTWNMGDAPPQKKIT
S---WFLSK--GQGKTRDDSADYIPHDIYIIGTQEDPQGEKEWLEIL--RKSLQ-EIT--
NISFKVIAIHTLWNIRIVVLAKPEHE---NRISHICTDNVKTGIANRLGNKGAVGV-SFM
FNGTSFGFVNSHLTSGSEKKHRRNQNYTSILRFLTLGDKKLSPFNITHRFTHLFWLGDLN
YRVELPPMDAENIIQKIKQQQ-YPDLLSFDQLLMEKKDQKVFLQFE--------------
---------------------------EEEITFAPTYRFERNTREKYAYTKQKATGIKYN
LPSWCDRVLWKSYPMVHVVCQSYGCTSDILTSDHSPVFATFEVGVTSQFVPKN-----DS
KY---AESQGQIEFLRCCATLKTKSQTKFYIEFHSSCLES-FVKSQEGENEDGNEGELVV
MFTEALPKLTPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRIEATESLVPFHVVLT
HHGERTGVFQGEIKLQTSQGKQREKLYDFVKTERDE-TAGQKLKG-TSSFDFPKDLEQPN
R-----KSKPAHLMAKEAAAVARFRGNASPFSDAQGKDDTTRST-PTDISNPNYMGVV-F
SQQVPAPGQLKQSPSSDQTLAGWTYDQQPKENVSVMGQRESCSTPSSQSPLSPKSSAQPT
ANRSSGPRSQ-EHGPADLGKSVSEPL-LQEEM--QQKPEMFDNPLYGAMSSKGKVAPKKE
QDYAAALRKELPVLPNPGFLPSKLQDADSSKSSN-K----QP----SPPFLVPTPRFRSY
TCSNQT---EEKTLS--EKAQVKQKPPPCLES-P------APLKKPVKPSRSEVGP-SSQ
GQ-----YSKPPLPTKSRAVLDKQNPKGRDYRESSELPHQGKHRPEEGP---VGRAAAP-
------------------------------------------------------------
------------------------------------------------------------
----------------------