Query Results 

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHRLPQKDPYAAED-----------EVNTLFP
RKMMSHNGMEDSGGGGTGVKKKRKKREPGEHEGAAKGSKDKEPKPKRKREPKEPKEPRKA
KEPKKAKE---PKEPKQKDGAKKTRKPREASGTKEAKEKRSCADSAARTKSKKA-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNTSLRSPEESTESADNQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTSARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGNSDIPERGSTDKEDNAEDKLDGLQKQTESSNDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVPSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDENLEHYFYSFVAMCRNVCRLPTWKDGGPPDATIYVEPITEER
AARTLYRIELLRKIREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQPPGSLCCLYQTNSKLYESLTYTQMSRTSE
SLESEPENLVKIEDR-DDHLVLPGGNLPDMTCENFISKVQDVISINHDESLLPESLDNMM
YGKKVLSREAGSFQESPN--TN--MDSRKDAIAISASRDGSCQPSGHETAITSGSS-LMS
SLEE-GVAQMNIKSGKHLLISIS-KEGDPCCSETGQRPESM-------GQLE-AKCLAS-
--PALDAGNGSGLV--DMCSLTVC--DSKRNLSSDQQLIDLLENKSLESKLILNQNQSDE
DEE-EEENE----------EETLVVATDTRERSEVLHLTEPAANIP-----R--E---K-
SQGFPLEEAK------------KGSLEIVRQTPGPQRSFP-PAACQCHCKHME-------
----------RWAHGL-GSD--EFEVEKPKA----YNPDLYRSKASNTA-V--EGEPTAL
PSEPFKVKHELLK-EPWKESAEGK--KSFSTY----TPEGSEPKS-EDMDFENKDD-YDQ
DGTCHSQDYPGKYSEEESKSSASGITGDLGEDPQETRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSNAGSRNSLSEAEVAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVDR-DAKARSLDQFSATHGHPSIILNGWH
GESAIDLSCSSEGSP-GATSPFPVSASTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIINGSLRRDDAAT-RRRRGRRKHAEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THSEGPGPVTSTPEPAATTNSQAEKAVPSKSLLDWLRQQA-DYSLDMPGFGANFS
DKPKQRRPRCKEPGKLDISSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMATTCTSPAPASLSSTTKSGPSATEKTAEDKPSSHDVKTD
MVAEDKPGPSPFS----DQSEPAITASSPVAFNPFLIPGVSPGLVYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDTPNP------NPEPAPGCEREPSSDQNYTESS-T
PLPPEREHVAQAGEGGLKDSSNDTN

-------------------------------MKMKI--QKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGSPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGVFSEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSGTQAPGNLCCLYQTNSKLYESLTYSQMSRTSE
SLENEPENLVRVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPSSFQESPS--TN--TESRKDVITISISKDGNCQSGGPEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEGELCCSEAGQRPENI-------GQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTTNIS--------R---EK
NQGFQ-DETK------------KGSLEVANQTPGLQRAFPAPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTNTIA-M--EGEPTAI
PSQPFKVKHELLK-EPWKESAEGQ--NVFPTY----PLEGSELKS-EDMDFENKDD-YDR
DGNCHSQDYPGKYSEEESKSSTSGITGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSAGSRTSLSEPEAAEHSFSNG
AALAAQIHKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKSIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAIPKEPGL------------------------
-----------RGFLPENKFNHTLAEPILRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSGDENCAEPS-A
PLPAEREHGAQAGEGALKDSNNDTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVARHCLPQQDLYTTEE-----------EADTLFP
RKVTSCNGMEDSGGGGTGVKKKRKKKEPGEQEGAAKGNKDREPKPKRKREPKEPKEPRKT
KELKKAKE---PKEPKQKEGAKKTRKPREASGTKEAKEKRCNADSAARTKSKKA-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTIQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPTQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKCGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKMK
NQLLLPELKNADWLTTCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQSSTDGTSDIPERGTTDKEDNAEDKLDGLQKQMENSSDG--
-------GEGLCGEKKDDSRPAQDSSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRAVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYNFVAMCRNVCRLPAWKDGGPPDATIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGGLCCLYQTNSKLYESLAYSQMSRTSE
SLESEPENLVKIESR-DDHLGLRGGSFPDVTCDNFISKVQGVISINHDESLLPESLENMM
FGK-VLSQEPGSFQEGPI--IN--AESRKDAIGISANRSASCRPSDREAEIAS-VS-LMD
TLEA-GVAQMNIKSGEPVLTPIS-KEREHCCDEAGQRPGSM-------GQLE-AKSIPS-
--TALDVGNESGFV--DMCSLSVC--DSKRNLSSDQKLMDLLENKSLESKLILSQNQSDE
EEE-EDENE----------GETLTVAAGTREKPEVLHLANPTANIP-----R--E---K-
SHGFHLDEAK------------KGSLEVVSQ-TGPPRAFP-PASCQCHCKHME-------
----------RWAHGL-GSD--EFEVEKPKA----YKPDLYKSKANNTT-V--EGEPTAI
PSEPFKVKPELLK-EPWKESAERK--KGFSTY----ASEGSEPKS-EDMDFENKDD-YER
DGTCHSQDYPGKYSEEESKSSASGIAGDLGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDSICHVVLKGKWPSSQ-QYEPSGTL-STAVLANSAGSRNSLSEPEAAEHSFSNG
ATLAAQVQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSATHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSANTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPTAAANGQAEKAIPSKSLLDWLRQQA-DYSLDVPGFGANFS
DKPKLRRPRCNEPGKLDISSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNAPMAATCTSTAPASLSSTTKGGIAAAEKTTEDKPSSPDEKAD
TLAEDKPGPSPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIAGLESQKRKKKKTKGDNPNP------NPEPAPGHEREPGTDQNCTESS-T
PLPPEREHVAQSGEGGLKDANSDTN

-----------------------------------------------LKVLSRSPMSDAS
DTWECKAQGPLAGSEEQQSHR---ATATEAG--GQCLCPEE------------QPDGALL
RRPSAQNGMQDTGAVGTGVKKKRKKKDLGEQEGGEKAAVEVKPK--RRREPKEPKEPKKA
K------EPKKQKEPKQREVTKKPRKPREPKAPKEPKDRKSGSEPGPRTRPKKS-SKEQG
PTPVEKKKKGKRKNEIPVDSLDLDQDLLSPSVQSPEESAESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASRMVQKET
H----PGGLTFEMEEFYVKYRNFSYLHCKWATL-EELEKDPRISQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

KQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRILEVAHTKDPDTGEEVTHYLVKWCSLPYEESTWELEEDVDPG
KIKEFEA

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQIPPEIKHMERPASESWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDTQGNPLPGIFKFQVVITTFEMILADCPELKKIQWRCVVIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPQQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDVVEESLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLSKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPEAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRFNEKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPEIKNADWLATCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKAEVLGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWNAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKLLSAEQGISDGAQDTAERGTMEKEESSGEKLEGLPKQETWTASTSQ
GAEDVAAGAGEAGEKRDEPSAAQDGSDSDRSCWPVSSALTARLRRLVTVYQRCNRKELPA
RSEMLVPGNHGYWLQDEVFRRASEMDSVNKEMQKRWTRREQADFYRTVSSFGVIYDQEKK
TFDWTQFRAISRLEKKTDESLEKYFYSFVAMCKNVCGLPLWKEDGKTEAGRILSQTCQ--
--EDQSCAELLRDAQESVLQCERLLHERLKLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTGIPGSETLCCLYQTNSKLYSSPLYSQVDRTCE
SLENETESQIKLENT-DSTMSQAGGSPPDANCETFMSKVRDIISSNYDESSLPDSLMCMM
YDEKVCNSEQSSLARDSPTCTD---VGSSIAKLSEGKLEGDEDPSSCDAEAMREAS-FLE
GLQV-GCDQMDCQNEEAEPSPST----------LESDPLRSVPAELCEAVQQ-KRDLGSP
APVLPEHRAMEGVISVGLYSPSLH--NYDMKVPPEQRFINLLQEKGMEAKAGPSQSHSEE
----DEEE-EDDDNS----EVAADIAEGLSGPRAR-ASCDEL------------------
------------EDVNSER---GSLELGTLEVPAEPGPEG-REDHSLD------------
------------------EE--NTLQHLPGQ----SQSRPFS----LP---APPLGALGT
QPLHA------GG-EAWGQ---EA--EGQAGCREALHPEPPGVKQ-EECE---IRDEEEK
TGNSQNQDGPEKYLEEESKSSASVLPGEI-DDLQDARAPTIAQLLQEKTLYSFSEWPKDR
VIINRIDNICHAILKGKWPSSSQQFE-TQSLLAAPAVASNAGSRNSFAESEAPDPSFNNG
-VLISQVPKEGFLNPAFAKDERKHRRLYEFELER-DAKQRSLEQLAAAHVHPPIVLNGWR
D-AAVDLSRASDGSP-GNSSPFPLNTNMPKLGTVN--TLQGSLGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKNVE-GMDLIFLKERPLPTRLQDIQ------DDQLQP
PQNS-PLPDGPAAATSTPQPVPAAGSQAEKAVPNKSLLDWLRQQS-DYTLDVPSFGTNFS
DKPKQRRQRCKDPSKLDISAL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

TGEERVPVVHKGTGR------------------------
-----------RGYLPESKFNRVLTEPVLR-DA-GP-RRRGRRPRSELIKGPGIV-ADSS
SGMGPLFMNGLIAGMDLVGLQNMRNMQGIPLTGLVGFPAGFAAVPAGEDVKSTLSMLPMM
LPSMATVPQMFGVGGLLNPPMATTCTATAPTSLTSTTKSGTSNAEKATEDKQSSQDAKKE
TLSEDKPGPSSFS----NQTESAITTSSPVAFNPFLIPGMSPGLIYPSMFLSPGIGMALP
GMQQARHAEAASLESQKRKRKKAKGDAANP------EPETVSLPEKEAANGQNCTEQT-P
PLPAEKEQDVPAEEEVKEVNDTN--

--------------------------------VISL--FQTKEKLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 565)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFNWYN---
------------------------

PF00176 // ENSGT00760000119067_8_Domain_2 (565, 811)

RGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGSPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGVFSEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSGTQAPGNLCCLYQTNSKLYESLTYSQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPSSVQESPS--TN--TESRKDVITISISKDGNCQSGGPEAEIASGPT-FMG
SLEAGRVAQANIKNGKHLLMSIS-KEGELCCSEVGQRPESI-------GQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTTNIS--------R---EK
NQGFQ-DETK------------KGSLEVANQTPGLQRAFPAPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTNTIA-M--EGEPTAI
PSQPFKVKHELLK-EPWKESAEGQ--NVFPTY----PLEGSELKS-EDMDFENKDD-YDR
DGNCHSQDYPGKYSEEESKSSTSGITGDIGDELQEARTPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSAGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TSST-THPEGPGPATSAPEPATAASSQAEKSIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAIPKEPGL------------------------
-----------RGFLPENKFNHTLAEPILRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPCGDENCAEPS-A
PLPAEREHGAQAGEGALKDSNNDTN

-------------------------------MKMKI--QKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGVKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQMESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPGSFRESPS--TN--TECRKDVITISISKDGNCQPGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEEDLCFSEAGQRPESI-------SQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTIDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTSTIA-M--EGEPTAV
GSEPFKVKHELLK-EPWKEGAEGQ--KVFPTY----PLEGSELKA-EDMDFENKDE-YDR
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSVGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSS
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAGDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGGNPNS------HPEPAPSCEREPSSDENCAEPS-A
LLPAEREHVAQAGEGALKDSNNDTN

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MVQKEV
H----PGELPFDM

PF00385 // ENSGT00760000119067_8_Domain_0 (374, 412)

ELFYVKYRNFSYLHCKWATM-EELEKDPRISQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDSDTGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 536)

SLQILPEIKHVERPASDSWQKLEKSREYKNNNQLREYQLEGMNWLLFNW

PF00270 // ENSGT00760000119067_8_Domain_2 (536, 667)

YNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMLYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLAKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDSLDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLTKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNEKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPELKNADWLATCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKSEVLGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVVKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGSQDMSERSNLDKEDNTEDKIDGLQKQLEDTSFG--
-------ESE----KKDENMAAQDGSDPDRSPWPVSSALTARLRRLVTVYQRCNRKE-PT
RAEILCPGNQGYWVQEDMFRRATEMDPLNKEIQKRWTRREQADFYRTVSSFGVVYDQEKK
SFDWTQFRVISRLDKKTDESLEKYFYSFVAMCRHVCRLPMWKDDGPPDPTLYVEPITEER
AARTLYRIELLRKVREQVLKYPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
SRTDYYIMNDPQLSFLDAYRNYAQHRRTEAQGPENACCLYQTNSRLYESLTYAQMGRTCE
SIDTEPENQIKMESMSDNNLSHTESNLPDVTCENFISKVQDIISINHDETLLPDSLECIM
FGEKVFKNEPSSFIQENS--SS--IESRKDVSVALASKNQENQPGSLEVEVATNRC-SLG
NLET-KIEQMSNKNEKHLSLLTI-KDLDSNKYTPAPRHETV-------RHPE-AKCSIP-
--QSLEPGNVSRLM--EMCSLSVC--NSERKFSSEQQLIDLLGNKNLEGKLMLSQNHSDE
EEEEEEEEE----------EENSEVGAHIRERPEGIGQTDLNIIIP--------S---EM
DRGFIITKTK------------EGGPETQNCDPAELRGI-DNTICECHCKPID-------
----------RWKNLG-DSV--EFEMEKTKF----SDPDLYKGKAVNTIT--LEGGNKTL
LSEPLKVDHELLKEDSWEDKTEMK--RGYTTC----PLNRSDLKQ--DVDFESKEDDDDK
DGNLQGQDYPGKYSEEESKSSTSGIAGDIGDELQETRAPTIAQLLQEKTLYSFSEWPKDR
VIINRIDNICHAVLKGKWPSSQ-QYEIPSTL-PAPVLISNPSSRNNLAEQETPGPNFSSG
AALVTQIPKESFLAPVFAKDERKHRRPYEFDMER-DLKSRNLEQFSASHGHSPIVLNGWR
GESAIDLSCAPDGSP-ATTSPFPLSTSTPKIGTVS--TLQGSLGMDLSGILQAGLIHPVT
GQIVNGTLRRDDAAM-RRRRGRRKNVEGGMDLIFLKERTLQTGILEVQ------EDQEQP
SPSS-THPDGPISATSSPHTVTTTSVQAEKTIPNKSLLDWLRQQS-DYTLEVPTFGTNFS
DKPKQRRQRCKEPGKLDMGSLSGEERVPAVPKETGR------------------------
-----------QGFLPENKFSQILTEPVLRD--AGP-RRRGRRPRSELIKTPGIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMQGIPLTGLVGFPAGFAAVPAGEDVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMTTTCTSTVPTSLTSTTKSGTSNTEKATDDKQNSHDVKKD
TLAEDKPVPSSFS----DQSEPAITTSSPVAFNPFLLPGMSPGLIYPSMFLSPSIGMTLP
GMQQTRHSENTSLESQKRKRKKAKGDTLNP------DPETVSVSEKESGNGQNCSEHT-P
LLPTDKEHGVQAEQSDLKGTLSDTN

-------------------------------------------QLSSSKVRSRSPMSDAS
DTWECKAQDPFASSEEQDEVP---QQATAAA--VGSQHPEE------------EPSRAPQ
KRPSAQNGMQDTGGVGTGVKKKRKKKDQGEQEGGEKAAVEVKPK--RRREPKEPKEPKKA
K------EPKKQKEPKQREVAKKPRKPREPKAPKEPKDKKSGSEPASRARPKKS-SKEQG
PTPVEKKKKGKRKNEIPVDTLELDQDLLSPSVQSPEESVELADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASRMVQKEA
H----PGGLTFEMEEFYVKYRNFSYLHCKWATL-EELEKDPRISQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

KQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRILEVAHTKDPDTGEEVTHYLVKWCSLPYEESTWELEEDVDPG
KIKEFEA

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQIPPEIKHMERPASESWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDSQGNPLPGIFKFQVVITTFEMILADCPELKKIQWRCVVIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPQQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLSKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPEAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRFNEKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPEIKNADWLATCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKAEVLGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWNAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKLLSAEQGVSDGAQDAAERGSMDKEESSGEKMEGLPKQEQ-------
--DMVAAGVGEAGEKRDEPSAAQDGSDSDRSCWPVSSALTARLRRLVTVYQRCNRKELPP
RAEMLVPGNHGYWLQDEMFRRASEMDSVNKEMQKRWTRREQADFYRTVSSFGVIYDQEKK
TFDWTQFRAISRLEKKTDESLEKYFYSFVAMCKNVCGLPLWKEDGPPDPDIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLKLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTGIPGSETLCCLYQTNSKLYSSPLYSQVDQTCE
SLETESESQIKLESI-DNTMSQSGGSPPDANCETFMSKVRDIMSSNYDESSLPDSLMCMM
YDEKACNSEQSSLARDSPSCTD---IGSGIAKLSEGKLEGDEDPSSCDAEAMRETS-FLD
GLQV-GCDQMDSQNGEAEPSPST----------PESDPSQSIPAELCEALQQ-KRDLTSP
A---PEHSAMEGVISMGLYGSSLH--NYDIKVPPEQRFINLLQEKGMEAKSAPSQSHSEE
----DEEEEEDDDNS----EAAADVAEDLSGPRTT-AGCDPETNELGG------E---EQ
SPGLPTPEDTCPEAVNGER---EALGLGTLEGPGEPGPEG-REDHSLE------------
------------------EE--SILQDLPGQ----AQSQAFS----PP---APPVGPPGA
EPSHA------RE-EDWGQ---GS--EGQAGCREAPHPEPPGMKQ-EECE---IRDEEEK
AASSQNQDGLEKYSEEESKSSTSVLPGEI-DDLQDARAPTIAQLLQEKTLYSFSEWPKDN
VLLSQRKGCCPVSL---WSLTAGNSTEPGAGLGPQRVPPAAGGAPRARAPWQKDVCVSCG
PWQCASSRKEGFLTPAFAKDERKHRRLYEFEVER-DAKQRSLEQLAATHIHSPIVLNGWR
E-AAVDLSRNSDGSP-GNSSPFPLNTNMPKLGTVN--TLQGSLGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKNVE-GMDLIFLKERPLPTRLQDVQ------EDQPQP
PQNT-PLPDGPVAATSTPQPVPAAGSQAEKAVPNKSLLDWLRQQS-DYTLDVPGFGTNFS
DKPKQRRQRCKDPSKLDINAL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

TGEERVPVVHKGTGR------------------------
-----------RGYLPESKFNRILTEPVLR-DA-GP-RRRGRRPRSELIKAPGVV-ADSS
SGMGPLFMNGLIAGMDLVGIQNMRNMQGIPLTGLVGFPAGFAAVPAGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLNPPMTTTCTATAPTSLTSTTKSGTSNTEKATEDKQSSQDVKKE
TLSEDKPGPSSFS----NQTESAITTSSPVAFNPFLIPGMSPGLIYPSMFLSPGIGMALP
GIQQTRHSEAANLESQKRKRKKAKGESANP------EPETVLLPEKEAANSQNCTEQT-P
PLSAEKEQDVPAEEELKEVNDTN--

----------------------------------IMKIQKKEKQFSNLKVLSRSPMSDAS
VTCEYKSQSSFVSSTDQEEKI---TDLASHCILEKELYPAE------------DADHLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPSEQEAVGKGVKDKEPKPKRKREPKEPKEPKKA
KEPKK------QKELKQKETVRKSRKPREPKLSKDAKDKRSSTDSTPKMKTKKAXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXSYLHCKWATM-EELEKDPRISQKIKRFRNKQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

IEVDRILEVAHTKDSDTGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQILPEIKHVERPASDSWQKLEKSREYKNNNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXGNPLSGIFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

INXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 958)

XXXXXXYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQX

ENSGT00760000119067_8_Linker_4_5 (958, 2602)

XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVQQLTKIEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKXXXXXXX
XXXXXXXXDPNFWQKWAKIAELDTDAKNEKESLID-RARXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPELKNADWLATCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKSEVLGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVVKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDSSQDISEXXXXXXXXXXXXXXXXXXXXX--------
-----EDTSFGESEKKDENMAAQDGSDPDRSPWPVSSALTARLRRLVTVYQXXXXKE-PT
RAEILGPGNQGYWVQEDMFRRATEMDPINKDIQKRWTRREQADFYRTVSSFGVVYDQEKK
SFDWTQFRVISRLDKKTDESLEKYFYSFVAMCRNVCRLPMWKDDGPPDPTLYVEPITEER
AARTLYRIELLRKVREQVLKYPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
SRTDYYIMNDPQLSFLDAYRNYAQHRRTEVQGPENACCLYQTNSRLYESLTYTQMGRTCE
SIDTEPENQIKMESMG-DNLNHTESNLPDVTCDNFISKVQDIISINHDESLLPDSLECMM
FGEKVFNSESSSFIQENPSSTE----SKKDVSVTLASKNKENQPGSLEVEVATNHC-SLG
NLEA-EIEQMSNKNEKQLSLLTI-KDMDSCSRHE-----TVRYP-------E-AKCG---
IPQPLEQGNVSRLM--EMCSLSVC--NSERKLSSEQRLIDLLGNKSLEGKLMLSQNHSEE
EEEEEEDEE----------EENSEVGAQIRARPEGIVRTDFNTNIPN-----------EM
VRGFTVDKTMV------------GGPESQNHDLPELRCLN-QTLCECHYKPID-------
----------RWKNQG-NSV--EFEMEKNKF----PDSDLYKSKAVNTI--AVEGGNKTL
LSEPLKVDHEFLKEDSWEDKVERQ--RGYTTC----PLDRSELKQ-EDVDFENKEDEDDK
DGNLQGQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXESFLAPVFAKDERKHRRPYEFDMER-DLKSRSLEQFSASHGHPPIVLNGWR
GESAIDLSCTPDGSP-AATSPFPLSTSTPKIGTVS--TLQGSLGMDLSGILQAGLIHPVT
GQIVNGTLRRDDAAM-RRRRGRRKNVEGGMDLIFLKDRTLQTGILEVQ------EDQEQP
SPSS-TLPDGPVSATSSPHTATTTSIPAEKTVPNKSLLEWLRQQS-DYTIEVPTFGTNFS
DKPKQRRQRCKEPGKLDMGSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPAVHKETGR------------------------
-----------QGFLPENKFSQILTEPVLRD--AGP-RRRGRRPRSDLLKAPGIV-ADSP
SGMGPLFMNGLIAGMDLVGLQSMRNMQGIPLTGLVGFPAGFAAVPAGEDVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMTTTCTSTVPTSLTSTTKSGTSNTNKATDDKQNSHDVKKD
TLAEDKPIPSSFS----DQSEPAITTSSPVAFNPFLLPGMSPGLIYPSMFLSPGIGMTLP
GMQQTRHSENTSLESQKRKRKKAKGDTLNP------DPETVPISEKESGNGQNCSEHT-P
LLPTDKEHGVQAEQSDLKGTHSDTN

---------------------------------MIMKIQKKEKQLSNFKVLNHSPMSDAS
VHFDYKSPSPFDYGTDQEEKI---EDVASQCLPQKNLFAAEE-----------EADTLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKNPGEQEGTAKGNKDREPKPKRKREPKEPKEPRKA
REPKKATE---PHEPKQKDGAKKPRKPREASGTNDPKEKRSGTDSADRMKSMKA-SKEQG
PTPVEKKKKGKRKSDTAVESLELDQGLPNSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--IIEKXXXXXXXXXXX
X----X-XXXXXXXXXXXXXXXXSYLHCKWATM-EELEKDPRIAQKIKRFRNKQAQMKHI
FTEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEESTWELEEDVDPA
KVKEFESLQVLPEMKHSERPASDSWQKLEKSRQYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLAKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKIEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--XXXASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNXXXXXXXXXXX-XXXXXXXX-XX
XXXXXXXXXXELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDVPERANTDKEDNAEDKLDSLPKQTESPSDGN-
--------DGILGEKKXXXXXXQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-TC
RPEALGPGNPGYWVQEEMFRRTSEMDLINKETQKRWTTREQADFYRAVSSFGVVFDQEKT
TFDWTQFRVISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDGGPPDPAIYIEPITEER
AARTLNRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLTFLDAYRNYAQHKRTDIQAPDSLCCLYQTNSKLYDSLAYSQLGRTSE
SLVHEPENLVKAESR-EDPPAPPQDSLPDITCDSFLSRVQDVLSIHHDESVLPEPLESTS
YGKKGLGQVPSSAQESPVRG-R--AEARRDTMALSASLEGDCQSRDCETERASAPS-FLG
LLEA-GVAQMNHKNGKHLLMSLS-KAGELCCSEARRRPEDF-------GHLE-AKCMSS-
--PSLDQGNESGFV--DMCNLSIC--NSKTSLSADQQLIDLLENKSLDSKLILGQSHSDE
EEEEEEEE------------ENLDLAAGLRKQPELLHLMEPTLTISRA------Q-----
SRGFQAGDPK-----R-------DSLEEVSRAHQPQRAVS-VATCQCHCELME-------
----------RWN-GI-ETE--DLEVEKSPG----YDLDLYKSTASSM---PVDTEPAAS
PSEPFKGRSELVK-EPWKESAEGT--KGFPTF----PLEGSELKP-EDTDFET-KEDYDR
ERHGHSQGYPGKYSEEESKSSPPGAAGDTGEDLQEARAPTIAQLLQEKTLHSFSEWPKDR
VIINRLDNICHVVLKGKWPSGQ-QYEPSGPL-PTPVLTSSAGSRNSLSEPEASEHSFSNG
PSLVAQIQKESFLAPVFTKEEQKHRHPYEFEVER-DAKARSLDQFSATHGHPPIVLNGWH
GESAIDLSCTSEGSP-GATSPFPVSASTPKIGTIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEEGMDLIFLKEQTLHAGILEVH------EDAGQA
SLST-THPEEPVPAASVPETVAATSSQAEKTIPSKSLLDWLRQQS-DYPLEVPGFGTXXX
XXXXXXXXXXXXXXKLDINSPS-EERVPTVK-EPGP------------------------
-----------RSFLPENKFNHALPEPVLRD--AGP-RRRGRRPRNELLKAPAIV-ADSA
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLNTPMTTACTSPAPASLPSTTKSGTLVSEKTAEDKPGSRNGKTD
ASAEDKPGSSPFP----DQSEPAITPSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
TMQQARHSDLVGLESQKRKKKKAKGDSTHP------NPEPAPGSEREPGSDQNCSEVS-A
PWPPDREHMAQAGDGGPKDSNHNTN

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
--------------EEDEGSKFCEEDIDQILQRRTQTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDTRNEKESLVLDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNEKTRRYLRAECFRVEKNLLIFGWGRWKDILAHGRFKWHLNETDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPELKNADWLASCNPEVVLHDTALQQLVPAHVRGVLLRVRMLYY-LKAEVLGE-AA
DKAFDGTPARELDVLLPDIDYVEIPVDWWNAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDAA----EQGAGDGVQEAAERWVGEQAQQAGSQPLP---QPLQPDSG--
------NSYGEAAEKQDDGAAAQDGSDTERSCWPVSSALTARLRRLGTIYQRCTRKELPP
RAEVLVPSNHGYWLQGEMFRRAAEMDPANKEMQKRWTRREQADFYRTVSSFGVIYDQEKK
AFDWSQFRAISRLEKKTDESLEKYFYSFVAMCRTVCRLPLWKEDGPPDPSIHVEPITEER
AARTLYRIELLRKVREQVLESPP-PPERLKL-----------------------------
----------------------------------------------YGSPPCGG----LE
SLERGAESQAKLEGL-EDALSRAEGSPQDTSCDTFLSTVRDIMSLTCEDSSLPDSLLGML
CEDKACPSEHGSLAHDSPSRV---------ARLAEGKLDGDCHGSWDQLDSPSGGG----
-----------------EPWP----------SATASQPSGRVPAETGD-----ASEQASP
GPRSPALPSAEGVISLGLYGPSLR--GLGLKIPPEQRFIGLLHKKGLEELGAPSH--SEE
EEGARRWQ------------QTLRKDRGAARRPGLV------------------------
---------------------------------------GTPALACCQGRPLGQA-----
-------FPPSWGRRGAGGGEESPAEHSPDC------PKS----------LPPAPSPKA-
-------GPASRAVGCWEAGGSA--------W----HLEGETLLQQEDDVDE-NKEEEEK
EGPSQSHGCPEKYSEEEAKSSPCALPGET-EELQDTRAPTIAQLLQEKTLYSFSEWPKDR
VIISRIDSICHAVLKGKWPSSSQQLET---------VASSAGPRSGFAESGTPHPSFSDS
A-LTAQVQGGSFLAPAFAKEERKHRQPFEFEPER-DAKARSLERLAAAHPCPPGVLNGWG
GRRTLRLSCSDRPSPAGARSPAPCSPSLPRRLTRLSRDLSPALGVSREALGPLLGPAPPV
GTAVTGWLRKGSSPPGEQARSRPPGCSGGQSLSGAQEKAAVAPLLGPA------PPVGTA
VTGW-ARPDRPGTAPSAPHTAPAPGVRPEKAAPNKSLLDWLSQQS-DYTLDVPAFSTSFA
DKPKQRRQRCKDPSKLDVH

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2678)

SLTGEERVPVVHKGTGR------------------------
-----------RGFLPESKFNRILTEPVLRD--AGP-RRRGRRPRSELIKAPGVS---DS
SGMGPLFMNGLIAGMDLVGLQNMRNMQGIPLTGLVGFPAGFAAVPAGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLNPPMTTTCTSTASASLTSTTKSGTSNTEKATDDKQSSQDVKNE
PLSENEPGPSSFS----DQTESAITTSSPVAFNPFLIPGMSPGLIYPSMFLSPGIGMPLP
GIQQTRHSEATNPESQKRKKKKTKGEPTNP------EPETVSLSEKEAANSQNCTEQT-P
SLSSEKAHAIPAEEKALKEINNTN-

---------------------------------MKMKIQKKEKQLSSLKVLNHSPMSDAS
VNFDVKSPSLFDCSTDQEEKV---DDVPRHCLSQRDVYTAEE-----------DADTLFA
SKMTSHNGMEDSGGGGTGVKKKRKKKESGEQASAVKGGKDREPKPKRKREPKEPKEPRKA
KEPRKAKE---PKEPKQKDGTRKARKPREASGTKEAKEKRNCSDSAARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQSLPNSSLRSPEECAESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

KQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQVLPEIKHVERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVVIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKI-GDFRKTHSPDAPDQVMIA-
-----AKLVLDKLLPKLIAGXXXXXXXXXXXXXXXXX-XX

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

XXXXXXYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVLLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKLLSAEQGVTDGPTDIPDRGNLEKEENTEDKLDGLQKQTESPSDG--
-------GDGTFCEKKDDSRTAQDGSDPDKSPWPASSALTARLRRLVTIYQRCNRKE-LC
RPEIMGPGNQGYWVQEEMFRRSSEMDLINKDAQKRWTRREQADFYRTVSSFGVIYDQEKK
TFDWTQFRMISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDGGSPDATIYVEPITEER
AARTLYRIELLRKIREQVLKCPE-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTARHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRNDAQAPGGLCCLYQTNSKLYESFTYTQMSRTSE
SLENEPENLVKIESR-DDPLSLPRSNLPDVTCESFLSKVQDVMSINHGEGRLPQS----L
YSKKKLCHEPGSFQESPG--AS--IEPQEDSVAISMSADGSCQPGCHEAELASSPS-VMG
SLEA-RVAQMNIKDGKHLLMPFS-KEGEPCRSEVGQRPETI-------RQLD-TTCLAS-
--PSSDPGNETGLV--DATTLSAC--DAKGNLSSDQQLIDILENKNLESKLILGQNHSDE
EEE-EEENE----------EENLNMVAGIREMPQVLQLSEPTPNIL--------C---EK
NRGLHVDEAQ------------EGSLGAGGQASGPQRAFP-PATCQCQCKHVE-------
----------QWPRGL-DCE--ELEGEKPEV----YNPDPYNIKISNIT-S--EGEPTDT
ALEPFQVTRGLLK-ERWKESSDGK--KGFPTY----IPEASELKS-EDLDFENKDD-YDR
DGTCHSQDYPGKYSEEESKSSASGIAGDTGDDVQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSSTL-PSPVLASSAGSRNSLSEPEAAEHSFSSG
AALASQIQKESFLAPVFAKDEHKHRRPYEFEVER-DAKARGLDPFSVAHRHPPVVLNGWH
GESAIDLSCSSEGSP-GATSPFPASASTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAS-RRRRGRRKHAEGGMDLIFLKEQTLQAGILEVH------EDSGPA
AQST-TRPEGPGAAASAPEPATVTNSQAEKAIPSKSLLDWLRQQA-DYSLEASGLAANFS
DKPKQRRPRCKEPGKVDVSSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SREERVPAVPTEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--VGP-RRRGRRPRGELLKAPAIV-ADSA
SGMGPLFMNGLIAGMDLVGLQNVRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNAPMATPCASPAPASLSSTTNSGTAVPEKTVEDKPSSHDMKTD
TLAEDKPAPSPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHTEAGGLESQKRKKKKTKADNINP------NPDPAAGAEREPGSDQNCPESS-A
PLPPEREHVTQAGGGGLRDSNDDTN

-----------F------------MIKIQKKIFLFFHLSLLRFSLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEDKI---EDVASHCLSQKDLYTAEE-----------DAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGEQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---PKEPKQKDGAKKARKPREASGTKEAKEKRSCADSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFELELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEIKHVERPASDAWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKYHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVADGTSDIPERGNTDKEDNAEDKLDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDGGPPDATIYIEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGSLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLMKIESR-DDHLSL-----PDVTCENLISKVQDVISINHDESLLPESLENVM
YSKKVLSQEPDSFQESPS--TS--TEARRDAAANSASQDGNCQSGGQEAEVALGPS-FLS
SLEA-RVAQVNIKNGKHLLMSTS-EEGEFCCNVAGPRPECI-------GQLE-TKCLAS-
--PSLDPGSESGFV--DMCNLSVC--DTKRNLSADQQLIDLLENKSLESKLILSENHSDE
EEE-EEENE----------EENLAVTTGMRERPEVLHLTEPTTNIP--------R---EK
SRGFHVNAAK------------KGDLEVVNQTPGPQRAFP-PAACQCHCKHME-------
----------RWTHGL-END--EFEMEKPEA----YNPDLYKSKTNNIT-V--EGEPTAI
PSEPFPVKHELLK-EPWKESAEER--KGFPTY----LLEGSELKS-EDMDFENKDD-YDR
DGNCHIPDYPGKYSEEESKSSTSGIAGDIGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPLGTL-PTPVLTSSAASRNSLSEPEAAEHTFSNG
TALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSAAHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSTSTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSVPEPAAAAGSQAEKAIPSKSLLDWLRQQA-DYSLEVPSFGANFS
DKPKQRRPRCKESGKLDISSLSGEEGVPAVPKEPEL------------------------
-----------RGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRGELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQSMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNAPMATTCTSTAPASLSSTNKSGTAATEKTSEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITASSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQSRHSEIVGLESQKRKKKKTKGDNQNP------NPEPAPSCEKEPSSDQNCTESS-A
LVPPERELVAQAGEGTLKDSNDTN-

----------------------------------MKKXXXXXXXLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQDEKI---EDVASHRLS

PF00176 // ENSGT00760000119067_8_Domain_1 (94, 811)

QKDLFAAAE-----------ETATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEAGEQEGAAKGSKDREPKPKRKREPKEPKEPRKT
KEPKKAKE---PKEPKQRDGVKKTRKPREASGTKEAKEKRSCTDSAARTKSKKS-SKEQG
PTPVEKKKKGKRKSESTVESLELDQGLPNSSLRSPEESTESADSQXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEPPEDDAN--IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRNKQAQMKHI
FTEPDEDLFNPDYVEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFESLQVLPEIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEMHRFLFNWYTXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRXXXXXXXXXXXXXXX
XXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQSQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNXXXXXXXXXXX-XXXXXXGE-AA
DKAIEGTPARELDVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHXXXXXXXXXXXXXXXX
XXXX----XXXXXXXXXXXXXXXXXXXXXXXXGNTDKEDNAEDKTDGLQKQTESSGDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEVLGPGNQGYWVQEEMFRRASEMDLINKEAQKRWTRRGQADFYRTVSSFGVVYDQEKK
IFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPARKDGGPADATIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDAPVPGSLCCLYQTNSKLYESLTYTQMSRTVE
SLESEPENLVKIESR-DDHLSLPGGNLPDMTCESFISKVQDVISIDHDESQLSETLESMM
CGKKVLSQEPGSFQESSGPSTE----SRKDTVAISANKDGN----GHKAEIAADSS-FMD
SLEA-GVAQMNIKNGNHLSVSAS-KEGEPCCSEMGQRPECI-------GQLE-AKCLAS-
--PSLDPGNESGFV--DMCNLRVC--DSKRNLSSDQQLIDLLESKSLESKLILSQNRSDE
KEEEENE------------EENLAMAVGMRDRPEVLHLTEHTTNTPR-----------EK
SLSFHVDEAR------------KGNPEAVGQPLGLQKAFP-SATCQCHCRHME-------
----------RWVRGL-ENN--EFEVEKPKA----YSPDLYKNKTNV----TMEEEPTAV
PSESFQVKHEPLK-EPWKESIERK--KGFPVY----LPKGTELKS-EDVDFENKDE-YDR
DGNCHQXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-STPVLASSAGSRNSLSEPEASEHSFSNG
AALAAQIQKESFLTPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSATHGHPPIVLNGWH
GESAIDLSCSSEGSP-GXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXEV------HEDPGQA
TLST-THSEGPGPATSTPEPAGATSSQAEKAVPSKSLLDWLRQQA-DYSLDVPSFGAXXX
XXXXXXXXXXXXXXXXXXXXXX-----------------------------------XXX
XXXXXXXXXXXXGFLPENKFNHSLVEPVLRD--AGP-RRRGRRPRNELLKAPTIV-ADSG
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFAAMPAGEEVKSTLSMLPMM
LPGVAAVPQMFGVGGLLNTPMATTCTPTAPTSLPSTTKSGTAVTEKT-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------

---------------------------------MNSVLRWDPCKLSKLRALNHSPMSDAS
VNFDYKSPSPFDCSPDQGENI---EEAANHCLPQKDFYTTEE-----------EADTLFS
RKLMSHNGMEDNGGRGTGVKKKRKKKEPGEQEGT-KASKDREPKPKRKREPKEPKEPRRA
KEPKRAKE---PKEAKQKDGVKKPRKPREASGTKEGKEKRSCTDCGPRTKPKKA-SKDQG
PTPVERKKKGKRKNETTVESLELDQSLPNPSLQSPEEPSESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 535)

SLQILPEVKPVERPASDAWQKLETSREYKNSNRLREYQLEGMNWLLFN

PF00176 // ENSGT00760000119067_8_Domain_2 (535, 811)

WYNRKN
CILADEMGLGKTIQSIAFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVVIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 848)

ING--AEEKILEDFRKAHSSEASDFQLQAM
IQAAGKL

PF00271 // ENSGT00760000119067_8_Domain_4 (848, 965)

VLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLSDKARRYLRAECFRVEKNLLTFGWGRWKDILTHGRFKWPLNEKDM
EVICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKTADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNIDKEDSAEDKVDGLQKQTASPSDG--
-------SDGIFGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEVFRRTSDMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKE
AFDWTQFRAISRLDKKSDENLEHYFHSFVAMCRNVCRLPTWKDDGPPDASIYVEPITEER
AAKTLYRIELLRKVREQVLTCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGSLCCLYQGNSKLYESLTYTPMSRTSE
SLESEPENLVKMDSR-DDHLCLPEAGLPDITCENFVSKVQEVISLDHDESLLPESLENMM
YGKTGLSQEPRSFQEAPS--TN--MQSRKKTVTVSASRDESCQLPGIEAEITSASS-LMS
SLEA-GVAKMNIKNGKHLLVSIS-EEGEPCCSETGRSPESR-------GRLE-ARCLAS-
--PTLDTGHESGFV--DLCSLSVY--DSKRNFSSDQQLIDLLENKSLENKLILNQSDE--
---EEEENE----------KETLAIVASTTEKPAVLDFTQPTASIP-----R--G---K-
NLSFHQDEAK------------KGRLEVGSKTPGPQRAFP-PSANQCHCKHIE-------
----------RWAHGL-GSE--ESEGEKPKA----YEPDPYRSKANNTT-V--EGEPAII
PTEPFKLKHELLK-EPWKESSEGG--KSFSMY----VPEGSEPKS-EEMDFENKDD-YEK
DGACHSQDYPGKYSEEESKSSASGIAGDLGEEAQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPCSH-QYEPSGAL-PTPVLSSSAGSRSSLSEPEATEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEEYSASHGRPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHIEGGMDLIFLKEQTLQAGILEVH------EDAGQT
TLNT-THPEGPGAASSASEPTAAASSQAEKAVPSKSLLDWLRQQA-DYSLDVPGFGASFS
DKPKQRRPRCKEPGKLDIGSLGGEERVSAVPKEPGL------------------------
-----------RGFLPESKFNHTLAEPVLRD--AGP-RRRGRRPRNELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEDVKNTLSMLPMM
LPGMATVPQMFGVGGLLNTPMATTCTTTASASLAS-TKSGASATEKTTEDELSGRDVKAD
SLVEDKPGPSPFS----DQSEPTITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQGRHSEMAGLETQKRKKKKTKGDNP--------TPEPASVCEREPGSDQNCTESS-V
TVSPEREHVAQAREEGLKDSNDDTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVPSHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKTRKPREASGTKEAKEKRSCTDSTARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGAPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
TLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSKEPGSFRESPS--TN--TESAKDVITISTRKDGNCQPGGHEAEIASSPA-FIG
SLEAGGVAQANIKNGKHLLMSIS-KEGELCCSEAGQRPESI-------GRLE-ANCLAS-
--PSLNPGNESGFV--DMCSLSIC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENFAMAAGVGERSEVLHLMEPTTDIS--------R---EK
SQGFHVDETK------------TGSLEAANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YNPDLFRSKTNTIA-M--EGEPTAI
PSELFKVKHELLK-EPWKESAEGQ--KVFPTY----PLEASELKS-EDIDFENKDD-YER
DGICHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICQVVLKGKWPSGQ-QYEPSGTL-PTPVRTSSAGSRTSLSEPEVAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSGTHGHTPIILNGWH
GESAIDLSCSSEGSP-GGTSPFSVSSSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLNT-THPEGPGPATLAPEPATAASSQAEKAIPNKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMATTCTSTAPVSLSSTTKSGTAVTEKTAEDKPSSHDVKTD
SLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIIGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDQNCTEPS-A
PLPTEREHVAQAGEGALKDSNNDTN

-------------------------------PWHRIQKSPKDGSLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVPSHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKTRKPREASGTKEAKEKRSCADSTARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMELINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGAPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LLERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
TLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMI
YGKQVLSKEPGCFRESPS--TN--TESTKDVITISTSKDGNCQPGGHEAEIASSPA-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEGELCCSEAGQRPESI-------GQLE-AKCLAS-
--PSLNPGNESGFV--DICSLSVC--DSKRNLSSDHQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENFAMAAGMGERSEILHLMEPTTDIS--------R---EK
SQGFHVDETK------------KGSLEAVNQTPELQRAFPPPAACECHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YNPDLFRSKTNTIA-L--EGEPTAI
PSELFKVKHELLK-EPWKESAEGQ--KVFPTY----PLEGSELKS-EDIDFENKDD-YER
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICQVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSAGSRTSLSEPEVAEHSFSNG
TARAAQIQKESFLAPAFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAIDLSCSSEGSP-GGTSPFSVSSSTPKIGAIS--SLQGTLGMDLSGILQAGLIHPVT
GQIVNGSFRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPAISAPEPATAASSQAEKAIPNKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAIPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--TGP-RRRGRRPRSELLKTPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMATTCTSTAPASLSSTTKSGTAVTEKTSENKPSSHDVKTD
SLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVSLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDQNCTEPS-A
PLPTEREHVAQAGEGALKDSNNNTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDDPSHCLPPKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKTRKPREASGTKEAKEKRSCADCTARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGIFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYGFVAMCRNVCRLPTWKDGAPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
TLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMI
YGKKVLGKEPGSFRESPS--TN--TESTKDVITISTSKGGNCQPGGHEAEIASSPA-FMG
SLEAERVAQANIKNGKHLLMSIS-KEGELCCNEAGQRPESI-------DQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLNVC--DSKRNLPSDQQLIDLLENKSLESKLILSQNHSDE
EE--EEENE----------EENFAMAAGMGERSEILQLMEPTTDIS--------R---EK
SQGFHVDETM------------KGSLEAANQTHGLQRAFPLPAACECHCKHME-------
----------RWMHGL-END--EFEIETPKT----YNPDLFRSKTNTIA-L--EGEPTAI
PSELFKVKHELLK-EPWKESAEGQ--KVFPTY----PLEGSELKS-EDIDFENKDD-YER
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICQVVLKGKWPSSQ-QYEPSGTL-PTPILTSSAGSRTSLSEPEVAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAIDLSCSSEGSP-GGTSPFSVSSSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSATEPATAASSQAEKAIPNKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMATTCTSTAPASLSSTTKSGTAVTEKTAEDKPSSHDVKTD
PLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSE-IGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDQNCTEPS-A
PLPTEREHVAQAGEGALKDSNNDTN

---------------------------------MIMKIQKKEKQLSHLKVLNHSPMSDAS
VNLDYKSPSPSDHSTDQEEKI---EDAASHCLPQKDLYAAEE-----------DAETPLP
RKTTSHNGTEDSGGGGTGVKKKRKKKDPGEQEGAAKGSKDREPKPKRKREPREPKEPRKA
KEPKRAKEPKEPKEPKPKDGARKARKPREASGAREAKEKRSSTDPAARAKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNXXXXXXXXXXX-XXXXXXXXXAQKIKRFRNEQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 496)

LQVLPEIK

PF00176 // ENSGT00760000119067_8_Domain_2 (496, 811)

HV---------------------------LEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKAHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHPTXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELEVPLPDIDYVEIPADWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGASDVPERGNTDKEDNTEDKVDGLQKQMENSSDGA-
--------DGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKEL-C
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPSIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMTDPQLSFLDAYRNYAQHKRTDPQAPESLCCLYPTNSKLYDSLTYAHMSRTSE
SLEHEPENLVKIEGR-DDHLGPPRGSLCDITCENFISKVQDVISITHDESLLPDSLESMM
YGKKVLSQEPGSFQESPGTNTE--SRPDALAVST--SRDGNCQSGGHEAELASGPS-LMD
TLEA-GVAQMNIKNEKHLLMSVS-KEGELCCSETGQRP-----EGI--GQLD-TKCLAS-
--PSLDQGNESGFV--DMCNLSVC--DSKRNLSSDQQLIDLLENKSLESKLILGQNYSDE
EEEEEENEDE-----------NLDLATGMRERPEVSPLTEPTAAMPR-----------EK
SFGFLVDEA-----KKGSLEARS-------QHPEPQGAFL-PTACQCHCKHM--------
---------ERWARGL-END--EFDVEKPQQ----YNPDLYKSKANNV---AVEGEPAAV
PSALFQVKRELLK-ELMKVRAEGH--QGFCSCREGSXXXXXXX-----------------
-----------------XXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXNSWHVVLKGKWPSSQ-QYEPVGTL-HTPLLTRSAGSRSSLSEPEASEHTFSNG
AALVAQMQKESFLAPVFTKDEQKHRRPYEFEVER-DVKTRSLEQFSATHGHPPIVLNGWH
GESAIDLSCTVEGSP-GATSPFPVSASTPKMGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVDGGVDLIFLKEQTLQAGILXXXXXXXXXXXXXXX
XXXX-XXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXNFS
DKPKQRRPRCKEPGKLDVNSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHSLPEPVLRD--AGP-RRRGRRPRSELLKAPTLV-ADSH
SGMGPLFMNGLIAGMDLVGLQNMRNVPGIPLTGLVGFPAGFAAMPTGEEVKSTLSMLPMV
LPGMAAVPQMFGVGGLLNAPMAASCTS-APASLSGTTKSGTSVAEKTAEDKPGGHDVKTD
SLAEDKPGPSPFS----DQSEPAITTSSPVAFNPFLIPGMSPGLIYPSMFLSPGMGMTLP
AMQQARHSEIVGLESQKRKRKKAKGDNPNP------NPESAPGPEREPGGDQNCPESR-A
PVPLDREHAAQAGKGAPDSHGDTN-

---------------------------------MIMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSLFDRSTDQDEKS---EDVGSHCLPQKDLYAAE------------EAETLFP
RKMTSHNGLEDSGGGGTGVKKKRKKKDPGEQEGVAKGSKDREPKPKRKREPREPKEPRKA
KEPKKAKE---PKEPKQKDGAKKMRKPREASGTKESKEKRNNVDSVARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNASLQSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXX
XXXPDEDLFNPDYIEVDRILEVAHTKDAETGEXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

XXXXXKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXLMALXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYNLIDGRVRGS-
--LRQATPHRFCTADSKNFVIVLCTR--AGGLGINLTLADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXRLNDKPSRSLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELEVPLPDIDYVEIPVEWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGTTDGTSDIPEXXXXXXXXXXXXXXXXXXXXXESSCDV--
-------G-DGTAEMKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWIQEEMFRRTSEVDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
IFDWTQFRIISRLDKKSDESLEHYFYSFMTMCRNVCRLPAWKDGGPLDPTIYVEPIPEER
AARTLYRIELLRKIREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMTDPQLSFLDAYRNYAQHKSTDSQAPESFCCLYQSNSKLYDSLTYTQMSRTSE
SLENGPETLGI-E--SRDDLGLPEGSLSDVTCENLISKVQDVISITHDENLLPESLESMM
YGKKALSQEPGSFQESPSTNSE-----FRKDVTISASKDGNSQPGSHESEIASDSS-LMS
SLEA-RVAQMNIKNGKHLLMSLS-KEGELCCNEVRQRPGSVMQ-------LE-AKCLAS-
--PSLDQGNESGFV--DMYNLSVC--DSKRNLSSDQQLIDLLESKSLESKLTLSQNHSDE
EEEENE-------------EESLHVATGLRERPETLHLTEPSDNIPR-----------EK
SRGFHLDEVK------------KGSLEVISPNLGPQRAFP-PTACQCHCKHME-------
----------RWAHGL-ENN--GFELEKPKG----YNPDLYKNKTNDT---AMEGEPTAS
PSEPFKVKHELLK-ESWKESTELK--KNFPTY----APEGSDLKS-EDMDFEGKDD-YDR
DGNGLSQDYAGKYSEEESKSSTSGIAGDIGDDLQESRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYESSSTL-PTSVLASSAGSRSSLSEPEASEHSFSNG
AALVAQIQKDSFLTPVFTKEEQKLRHPYEFEVER-DTKSRSLDQFSAPHGHPPIILNGWH
GESAIDLSCTSEGSP-GATSPFPVSASTPKVGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAM-RRRRGRRKHVEAGMDLIFMKDQTLQAGILEVH------EDSGQA
SLST-PHPEGTAPAASAPEPAPAASSQAEKSIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVNSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPAIPKEPGV------------------------
-----------RGFLPENKFNHTLTEPSLRD--AGP-RRRGRRPRNELLKAPTIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMATTCTSAATAPLSSTTKSGTPVTEKTVEDKPGSHNVKTD
TLAEEKPSPSSFS----DQSEPAITASSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKAKGDNSNP------SLEPASGSEKETGGDQNCPESR-A
SVPPEREHAPQTREGVLKDSNSDTN

---------------------------------LRKGVGKNERELSSLKVPNHSPMSDAS
VNFDYTSPSPFDHSTDQEEKI---EDVASHCPAPKELYDVEE-----------EAGPLFP
RKTASHNGMEDSGGGGTGVKKKRKKKDPGEHEGAAKGSKDREPKPKRKREPRELKEPRKA
KEPRKAKE---PREPKQKDGTKKTRKPREASGPREAKEKRGGPDAAARTKSRKA-SKEQG
PTPVEK-KKGKRKSETAVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 523)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 809)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLSKGANQHNMPNLINTMMELRKCCNHP

ENSGT00760000119067_8_Linker_2_4 (809, 881)

YLISG--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKSEKESLVLDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKLLSAEQGVTDGASDVPERGHTDKEDNTEDKVDGLQKQMESSSDG--
-------GDGLFAEKKDDTRAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEVLGLGNQSYWVQEEMFRRSSEMELINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRVISRLDKKSDESLEHYFYSFVSMCRSVCRLPAWKDGGPPDPSIYVEPITEER
AARTLYRIELLRKVREQVLTCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYVMTDPQLSFLDAYRNYAQHKRPDPQAPESLCCLYQTNSKLYESLAYTHMSRTSE
SLENEPENLMKIEAG-DDHLGPPRGSLSDMTCESFISKTQDVLSLTHDESLLPGSLETMR
YGKKALSQEPGPFQGSTG--AS--TESRQDTAAISAGRDGNCQPRGHEAKIASDPS-FME
TLEA-GVAQMNIKNEKHLLISLS-KEGELGCSEAGPRPERI-------GQLD-PNCFAS-
--PSLDPGNESGFV--DMCNLSVC--DSRRNVSSDQQLIDLLESKSLESKLVLGPNHSDE
EDD-EDENE----------EESLELAAGRRERLAASPLSEPTTRMA-----G--E---QS
LAGFLTEEAK------------KGSTEARSQPPGPQGPFL-PTACQCHCKHVE-------
----------RWARGL-EKD--EFEVEKPQA----YPPDPFTSKANNVT-V--RGEPTAV
PPELLQVKQELLK-EPWKESTEGN--QGLPPY----P-EGSELKP-EDMDYESKEE-LDK
DGNCQSQDYPGKYSEEESKSSTSGITGDLGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIISRLDNICHVVLKGKWPSSQ-QHEPSGTL-PTPVLTSSTGPRGGISEPEASEHSSSSG
AAWVAQMQKESFLAPVFTKDEQKHRHPYEFEVER-DAKTRSLEQFSASHGHPPIVLNGWH
GESAIDLSCPSEGSP-GATSPFPVSASTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAS-RRRRGRRKHVDGGVDLIFLKEQTLQAGILEVH------EDPGQA
PLSTPHPPEGPVPATSTPEPTPAAGSPAEKAIPSKSLLDWLRQQA-DCSLEVPGFGANFS
DKPKQRRPRCKEPGTLDVT

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2678)

SLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLPEPVLRD--AGP-RRRGRRPRSELLKTPALV-ADAP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFAAMPPGEEVKSTLSMLPMV
LPGMAAVPQMFGVGGLLNTPMATTCASAVPAPLSSTTKGGVSAAEKTAEDQPGSHNVKTD
PSAEDKPGPSPFSS---DQPEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEAAGLESQRRKRKKTKGDAPNP------NPEPVPGLEREPGSEQSCPEPR-A
PAPPDREHAAQAREGGPQDSHGDTN

-------------------------------MKMKI--QKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCTTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 536)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFNW

PF00270 // ENSGT00760000119067_8_Domain_2 (536, 667)

YNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGSPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGVFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVENR-DDHLSL-----PDVTCEDFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPGSFQESPS--IN--TESRKDVITIPISKDGNCQSGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEGELCCSEAGQRPESI-------GQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLVMAVGMGERPEVLHLTEPTTDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTNTIA-M--EGEPTAI
PSQPFKVKHELLK-EPWKESAEGQ--DVFPTY----PLEGSELKS-EDMDFENKDD-YDR
DGNCHSQDYPGKYSEEESKSSTSGITGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSAGSRTSLSEPEAAEHSFSNG
AALVAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKSIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVS

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2675)

SLSGEERVPAIPKEPGL------------------------
-----------RGFLPENKFNHTLAEPILRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSGDENCAEPSSA
PLPAEREHGAQAGEGALKDSNNDTN

---------------------------------MKMKIQKKEKQLSKLRALNHSPMSDAS
VNFDYKSPSPFDCSPDQGENI---EEAANHCLPHKNLYTTEE-----------EADTLFS
RKLTSHNGMEDSGGRGTGVKKKRKKKEPGEQEGT-KGSKDREPKPKRKREPKEPKEPRRA
KEPKRAKE---PKETKQKDGVKKPRKHREASSTKEGKEKRSCTDYGSRTKSKKA-SREQG
PTPVERKKKGKRKNETTVESLELDQSLPNPSLQSPEEPSESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEVKHVERPASDAWQKLETSREYRNSNRLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSIAFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKAHSSEASDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLSDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWPLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNIDKEDSAEDKLDGLQKQTASPSDG--
-------SDGIFGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
AFDWTQFRVISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDDGPPDASIYVEPITEER
AAKTLYRIELLRKVREQVLMCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGSLCCLYQSNSKLYESLTYTPVSRTSE
SLESEPENLMRMESR-DDHLCLPEGGLPDITCENFVSKVQEVISLDHDENLLPESLENMI
YGKTGLSQEPHSFQEAPT--TN--TQSRKNTITISASRNESCQPPGIEAEITSASS-LMS
SLEA-GVAKMNIKNGKHLLVSIS-KEGEPCCSETGRRPETI-------GHRE-AKCLVS-
--PTLDTGHESGFV--DLCSLSVY--DPKRNFSSDEQLIDLLENKSLESKLILHQSDE--
---EEEENE----------DDTLAIVASTTEKPEVLDFPKPTVNIP-----R--G---K-
NLNFHQDEAK------------KGRLEVVSKTAGPQRVFP-PPANQCHCKHIE-------
----------RWAHGL-GSE--DSEVEKPKA----YQPDLYRSKANNTT-V--EGEAAII
PPETLKLKHELLK-EPWKASSEGG--KSFSMC----VPEGSEPKP-EDMDFENKDD-YEK
DGTCHSQDYPGKYSEEESKSSASGVAGDLGEEAQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPCSH-QYEPSGAL-PTPVLSSSAGSRSSLSEPEATEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEEYSATHGRPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVGASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHIEGGMDLIFLKEQTLQAGILEVH------EDAGQT
TLST-THPEVPGAASSAPEPTAAASSQAEKAVPSKSLLDWLRQQA-DYSLDVPGFGTSFS
DKPKQRRPRCKEPGKLDISSLSGEERVPAVPKEPGL------------------------
-----------RGFLPESKFNHTLAEPVIRD--AGP-RRRGRRPRNELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEEVKNTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMATTCTTTASASLAS-TKSGTSATEKSTEDKLSGHDVNTD
ALVDDKPGPSPFS----DQSEPTITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEMVGLETQRRKKKKTKGDSP--------TQEPASVCEKEPGSDQNCTESS-A
TVSPEREHGAQAREEGLKDSNDDTN

---------------------------------MIMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDHSTDQEDKT---EDVARPCLPQKDLHTAEE-----------DAETLFP
RKTTSHNGTEDSGGGGTGVKKKRKKKDPGEQEGAAKGSKDREPKPKRKREPREPKEPRKA
KEPRKVKE---PKEPKQKDGAKKVRKPREASGPKEAKEKRSGPDSAARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

XXXXXXXX
XXXPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQVLPEVKHVERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKSEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLSDIDCVEIPVDW-DAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNTEDKVDGLQKQMESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARXXXXXXXXXXXXXXX-XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFHSFVAMCRHVCRLPAWKDGGPPDPSICVEPITEER
AARTLYRIELLRKVREQVLQCPQ-LHERLQLCRPSLSLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMTDPQLSFLDAYRNYAQHKRTDPQAPGSLCCLYQTNSKLYESLAYTQMSRTSE
SLENEPENLVKIEGR-DDHLGPPRGSLSDMTCENFISKVQDVISITHDESLLPESLESMM
YGNKALSQEPVSFQSPG---TS--TESRQDAVALATSRDGNFQPGA--AEIASGSS-FMD
XLEA-GVAQMNIKNGKHLLVSLS-QEGELCCSEAGQRPESL-------GQLE-TKCIAS-
--PSLDQGNESGFV--DMCNLSVY--DSKRNLSSDQQLIDLLECKSLESKLILGRNHSDE
EEE-EEENE----------EENLDLAAGTRERPEVSPLTEPTARMA-----G--E---KS
HSGFLVDEAK------------KGSLAARSQHPGPQGAFL-PAACQCHCKHME-------
----------RWTHGLLEND--QFEVEKPQG----YNPDPYKSKANNVT-V--GGELTAV
PPELFQVKHEHLK-EPWKESAEGK--QGFPTY----L-EGSELKA-EDVDFESKDD-YDR
DGNCQSQDYAGKYSEEESKNSTSGIVGDLRDNLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSNQ-QYEPSAAL-PTPVLTSGAGPRSSLSEPEASEHVFSSG
AALVAQMQKESFLASVFTKEEQKHRRPYEFEVER-DAKTRGLEQFPATHGHPPIVLNGWH
GESAIDLSCPSEGSP-GATSPFPVSASTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVDGGVDLIFLKEPTLQAGILEVH------EDPGPA
PLSTSHPPEGPVPATSTPEPAPVAGSQAEKAIPSKSLLDWLRQQA-DCPLEVPGFGANFS
DKPKQRRPRCKGPGKLDVNSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLPEPVLRD--SGP-RRRGRRPRSELLKAPALV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPSIPLTGLVGFPASFAAMPTGEEVKSTLSMLPMV
LPGMAAVPQMFGVGGLLNAPMATTCASAVPAPLSSTTKSGTSAAEKTAEDQPSGRDVKTD
TSAEDKPGPSPFS----DQAEPPITTSSPVAFNPFLIPGVSPGLIYPSMFVSPGMGMALP
AMQQARHSEIVGLESQKRMRKKTKGDNPDP------SPEPAPGLEREPGGAQSCPESR-A
PAPPERGHAAQAGEGGPQDSNSVTN

---------------------------------MKMKIQKKEKQLSKLRALNHSPMSDAS
VNFDYKSPSPFDCSPDQGENI---EEAANHCLPHKSLYTTEE-----------EADTLFS
RKLTSHNGMEDSGGRGTGVKKKRKKKEPGEQEGT-KGSKDREPKPKRKREPKEPKEPRRA
KEPKRAKE---PKETKQKDGVKKPRKHREASGTKEGKEKRSCTDYGSRTKSKKA-SREQG
PTPVERKKKGKRKNETTVESLELDQSLPNPSLQSPEEPSESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEVKHVERPASDAWQKLETSREYRNSNRLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSIAFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 848)

ING--AEEKILEDFRKAHSSEASDFQLQAM
IQAAGKL

PF00271 // ENSGT00760000119067_8_Domain_4 (848, 965)

VLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLSDRARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWPLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNIDKEDSAEDKLDGLQKQTASPSDG--
-------SDGIFGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
AFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDDGPPDASIYVEPITEER
AAKTLYRIELLRKVREQVLMCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGSLCCLYQSNSKLYESLTYTPVSRTSE
SLESEPENLMRMESR-DDHLCLPEGGLPDITCENFVSKVQEVISLDHDENLLPESLENMI
YGKTGLSQEPHSFQEAPT--TN--TQSRKNTITISASRNESCQPPGIEAEITSASS-LMS
SLEA-GVAKMNIKNGKHLLVSIS-KEGEPCCSETGRRPETI-------GHRE-AKCLVS-
--PTLDTGHESGFV--DLCSLSVY--DPKRNFSSDQQLIDLLENKSLESKLILNQSDE--
---EEEENE----------DETLAIVASATEKPEVLDFPKPTVNIP-----R--G---K-
NLSFHQDEAK------------KGRLEVVSKTAGPQRVFP-PPANQCHCKHIE-------
----------RWAHGL-GSE--DSEVEKPKA----YQPDLYRSKANNST-V--EGETAVI
PTEPFKLKHELLK-EPWKESSEGG--KSFSMY----VPEGSEPKP-EDMDFENKDD-YEK
DGTCHSQDYPGKYSEEESKSSASGIAGDLGEEAQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPCSH-QYEPSGAL-PTPVLSSSAGSRSSLSEPEATEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEEYSATHGRPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHIEGGMDLIFLKEQTLQAGILEVH------EDAGQT
TLST-THPEVPGATSSAPEPTAAASSQAEKAVPSKSLLDWLRQQA-DYSLDVPGFGTSFS
DKPKQRRPRCKEPGKLDISSLGGEERVPAVPKEPGL------------------------
-----------RGFLPESKFNHTVAEPVLRD--AGP-RRRGRRPRNELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEEVKNTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMATTCTTTASASLAS-TKSGTSATEKSTEDKLSGHDVNTD
ALIDDKPGPSPFS----DQSEPTITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEMVGLETQKRKKKKTKGDSS--------TQEPVSVCEKEPGSDQNCTESS-A
TVSPEREHVAQAREERLKDSNEDTN

------------------------------------------------------------
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--------------------------------M-EELEKDPRIAQKIKRFRNKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 536)

SLQVLPEIKHVDRPASDAWQKLEKSREYKNSNQLREYQLEGMNWLLFNW

PF00176 // ENSGT00760000119067_8_Domain_2 (536, 811)

YNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPTQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLVFSQMVRCLDIL-EDYLIQRRYTYERIDGRPSTDS
VSQTQTALSFFCAPEREAWGSISQLLIPASYLILTGTHKMTCR-----------------
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--------------------------------M-EELEKDPRIAQKIKRFRNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKSHSSDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRPSTGS
VSQTQTALSFFCAPEREAWGSISQLLIPASYLILTGTHKMTCR-----------------
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---------------------------------------VSIKILSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVTRHCLPQQDLYTTEE-----------EADTLFP
RKVTSCNGMEDSGGGGTGVKKKRKKKELGEQEVAAKGNKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---PKEPKQKDGAKKTRKPREASGTKEAKEKRSCADSAARTKSKKA-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTIQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQIPPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFFRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPTQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAHDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKMK
NQLLLPELKNADWLTTCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVLLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGGTDGTSDIPDRGNMDKEDNTEDKLDGLQKQTENSSDG--
-------VEGIFGEKKDDSQAAQDSSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYNFVAMCRNVCRLPAWKDGGSPDASIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPDSLCCLYQTNSKLYESLTYTQMSRTSE
SLESEPENLVKIENR-DDHLGLSGGSFPDVTCDNFISKVQDVISINHDESLLPESLENMM
YGKKVLNREPGSFQECPV--IN--TESRKDAVNILASKNTSCQPGDHEAEIAS-VS-VMD
SLEA-GVAQMNIKSGKPSLTPIS-KERERCCSEAGQRPESI-------GQLE-AKRLPS-
--PALDTRNESGFV--DMCSLSVC--DSKRNLSSDQKLIDLLENKSLESKLILSQNQSDE
EE-EEDENE----------EETLAMAAGTREKPEIVHLTKPTGNVP-----R--E---K-
TQGFHLNEAK------------KGSLEVVSQPPGPPRAFS-PASCHCHCKHME-------
----------RWMHDL-GND--EFEVEKPKA----YNPVLYRSKANNTT-V--EGEPTAI
PSEPFKVKPELLK-EAWKESAEGK--KGFSTY----VAEGSEPKS-EDMDFENKDD-YDR
DGTCHSQDYPGKYSEEESKSSASGIAGDLGDDPQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDSICHVVLKGKWPSSQ-QYEPSGTL-SAPVLANSAGSRNSLSEPEVAGHSLSSG
ATLAAQVQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSATHGHPPIILNGWH
GESAIDLSCSSEGSP-GASSPFPVSANTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGSGPATSAPEPAAAANGQAEKAIPSKSLLDWLRQQA-DYSLDVPGFGANFS
DKPKQRRPRCKEPGKLDISSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNMPGIPLTGLVGFPAGFAAMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNTPMATTCTSTAPASLSSTIKSGTTATEKTTQDKPSSHVVKPD
TLAEDKPGPSPFS----DQSEPAITTNSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNP------NAEPAPGCEREPGSDQNCSESS-T
PLPPEKEHVAQVGEGGLKDSSNDTN

---------------------------------MIMKIQKKEKQLSSLKVPNHSPMSDAS
VNFDYTSPSPFDHSTDQEEKI---EDVASHCPAPKELYDIEE-----------EAGPLFP
RKTASHNGMEDSGGGGTGVKKKRKKKDPGEHEGAAKGSKDREPKPKRKREPRELKEPRKA
KEPRKAKE---PREPKQKDGTKKARKPREALGPREAKEKRGGPDAAARTKARKA-SKEQG
PTPVEKKKKGKRKSETAVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKSEKESLVLDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKLLSAEQGVTDGASDVPERGNTDKEDNTEDKADGLQKQMESSSDG--
-------GDGLFAEKKDDTRAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEVLGLGNQGYWVQEEMFRRSSEMELINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRVISRLDKKSDESLEHYFYSFMSMCRSVCRLPAWKDGGPLDPSIYVEPITEER
AARTLYRIELLRKVREQVLTCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYVMTDPQLSFLDAYRNYAQHKRPDPQAPESLCCLYQTNSKLYESLAYTHMSRTSE
SLENEPENLMKIEGR-DDHLGPPRGSLSDMTCESFISKTQDVLSLTHDESLLPGSLETMM
YGKKALSHEPGPFQSSTG--AI--TESKQDTMAIPASRDRNCQPRGHEAKIASDPS-FME
TLEA-GVAQMNIKNEKHLLMSLS-KEGELGCSEAGPRPESI-------GQLD-SNCFAS-
--PSLDPGNESGFV--DMCNLSVC--DSRRNLSSDQQLIDLLESKSLESKLVLGPNHSDE
EDD-EDDNE----------EESLELAAGRQERLAASPLSEPTTRMT-----G--E---QS
LAGFLTEEAK------------RGSTEAASQPPGPQGPFL-PTACQCHCRHVE-------
----------RWTRGL-EKG--EFEVEKPQA----YPPDPFTSKANNVT-M--RGEPTAV
PPELFQVKQELLK-EPWKESTEGT--QGLPPY----P-EGSELKP-EDMDYESKEE-FDK
DGNCQSQDYPGKYSEEESKSSTSGITGDLGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICQVVLKGKWPSSQ-QYEPSGAL-PTPVLTSSAGPRSSLSEPEASEHSFSNG
AALVAQMQKESFLAPVFTKDEQKHRHPYEFEVER-DVKTRSLEQFSATHGHPPIVLNGWH
GESAIDLSCPSEGSS-GATSPFPVSASTPKIGAVG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAS-RRRRGRRKHVDGGVDLIFLKEQTLQAGILEVH------EDPGQA
PLSTPHPPEGPVPATSTPEPTPAAGSPAEKAIPSKSLLDWLRQQA-DCSLEVPGFGANFS
DKPKQRRPRCKEPGTLDVTSLSGEERA-AVPKEPGL------------------------
-----------RGFLPENKFNHTLPEPVLRD--TGP-RRRGRRPRSELLKTPALV-ADAP
SGMGPLFMNGLIAGMDLVGLQNVRNVPGIPLTGLVGFPAGFAAMPPGEEVKSTLSMLPMV
LPGMAAVPQMFGVGGLLNAPMATTCASAVPAPLSSTTKGGASAAEKTVEDQPSSHNVKTD
PSAEDKPGPNPFSS---DQPEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEAAGLESQRRKRKKTKGDAPNP------NPEPVPRLEREPGSEQSCPEPR-A
PAPPDREHAAQAREGGPQDSHGDTN

------------------------------------------------------------
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--------------------------------M-EELEKDPRIAQKIKRFRNKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSSDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLVFSQMVRCLDIL-EDYLIQRRYTYERIDGRPSTGS
VSQTQTALSFFCAPEQEAWGSISRLLIPASYLILTGTHRMTCR-----------------
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--------------------------------L-EELEKDPRISQKIKRFRNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 486)

EVDRILEVAHTKDPDTGEEVTHYLVKWCSLPYEESTWELEEDVDPV
KIKEF

ENSGT00760000119067_8_Linker_1_4 (486, 533)

EALQIPPEIKHMERPASESWQKLEKSREYKNSNQLREYQLEGMNWLL

PF00176 // ENSGT00760000119067_8_Domain_4 (533, 1181)

FNWYNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDTQGNPLPGIFKFQVVITTFEMILADCPELKKI-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------HWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPEIKNADWLATCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKAEVLGD-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWNAEADKSLLIGVFKHGMLPACVGGGQQVRGV
CVEHLARATGPEVDVVCVLPHPYEGQ-------------SCSHALQ-L------------
---------CRA------------------------------RTALSSHLQLCRVKAALS
------------------------------------------------------------
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-------------------------

-----------------------------------MKIQKKEKQLSNLKVLNHSPMSDAS
VNFDFKSPSPFDCSTDQEDKI---DGVARHCLPQKDLYAAEE-----------EADTLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGEQAGTAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---PKEPKQKDGAKKARRPREASGTKEAKEKRNCSDSTGRTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPSSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 536)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFNW

PF00270 // ENSGT00760000119067_8_Domain_2 (536, 667)

YNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKVEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARDLDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNMDKEDNTEDKLDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPASSALTARLRRLVTVYQRCNRKE-LC
RPEIMGPGNQGYWVQEEMFRRSSEMDLINKDAQKRWTRREQADFYRTVSSFGVIYDQDKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRSVCRLPVWKDGGPPDATIYVEPITEER
AARTLYRIELLRKIREQVLTCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTARHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTNTQAPGSLCCLYQTNSKLYESLTYTQRSRTSE
CLENEPENLVKIESR-DDPLSLPGGSLPDVTCENFLSKVQDVMSISHGESLLPESLENVM
YSKKVLCRQPGSFQESPG--TS--AEPRKDAAAMSVGTDGSCQPGRHEAEVAPSPS-FMG
SLEA-GVAQMNIKDGKHLLMPVS-KEGEPCCHEVGQRPETI-------GQLD-TKCLPS-
--PSSDPGNESGLV--DMCNLSVC--DSKGNLSSDPQLIDVLENKSLASKLILGQNHSDE
EEE-EEENE----------EESLAVVAGMREMPPVLHLSEPSPNIL-----R--E---K-
SRGLHVDETQ------------KGSLEAGGQTPGPQRAFP-SEACQCHCKHME-------
----------RWARGL-EHE--EFEVEKPKT----YNPDPYSINTSSIS-M--EAEPTAV
APEPFQVTRGLLK-EPWKESAEGK--KGFPMY----VPEGSDLKS-EDLEFENKDD-FDR
DGACHSQDYPGKYSEEESKSSTSGIAGDTGDDVQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QCEPSGTL-PTPILPSSVGSRSGLSEPDAAEHSFSNG
AALAAQIQKESFLAPVFAKDEHKHRRPYEFEVER-DAKARSLDQFSATHRHPPIVLNGWH
GESAVDLSCSSEGSP-GATSPFP-----------------------------AGLIHPVT
GQIINGSLRRDDAAS-RRRRGRRKHAEAGMDLIFLKEQTLQAGILEVH------EDPGQA
ALST-THPEGPGPAASASEPAAVTNSQAEKALPSKSLLDWLRQQA-DCSLEVPGFGANFS
DKPKQRRPRCKEPGKLDIS

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2671)

SLSGEERVPAVPKEPGL------------------------
-----------RGFLPESKFNHTLAEPVLRD--VGP-RRRGRRPRGELLKAPAIV-ADSA
SGMGPLFMNGLIAGMDLVGLQNVRNVPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMATTCASPAPASLSSTTNSGAATTEKTVEDKPGSHNVKTD
TLAEDKPGPSPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIGALESQKRKKKKTKADSANP------NPDPAPGAEREPGSHQNCPESS-A
PLPPEREHVAQAGEGTLKDSSDDTN

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-----------------------------------------------M

PF00176 // ENSGT00760000119067_8_Domain_2 (529, 612)

NWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQVKSAYCTGHRG------------------------------
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---------------------------------MKMKIQKKEKQLAKLKALNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVANHCLPQKDLYTTEE-----------ESDTFFS
RKLMSHNGMEDSGGRGTGVKKKRKKKDPGEQEGT-KGSKDREPKPKRKREPKEPKEPRKA
KEPKRAKE---PKEAKQKDGVKKPRKLREASGIKEAKEKRSCTDYVSRTNSKKA-SKEQG
PTPVERKKKGKRKNETTVESLELDQSLPNPSLRSPEEPTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEVKHVERPASDAWQKLETSREYKNSNRLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKAHSSEASDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNIDKEDSAEDKLDGLQKQTASPSDG--
-------SDGIFGEKKDDSQAAQDGSNPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEVFRRSSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
AFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPTWKDDGPSDASIYVEPITEER
AAKTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGSLCCLYQTNSKLYESLTYTQMSRTSE
SLESEPENLVKMESR-DDPLCLPEGSLSDITCENFISKVQEVISIDHDESLLPESLENMM
YGKTGLSREPRSFQETPS--TN--TQSRKDTVTISANRDESCQPAGTEAEITSSSS-LMS
SLEA-GVAKMNIKNGKHLLISIS-KEGEPCCSETARRPESM-------GHLE-AKCLAS-
--PTLDTGHESGFV--DLCSLSVC--DSRRKLSSDQQLIDLLENKSLESQLILSQNQSDE
EEE---END----------DDTLAIVASATEKPESLHFTKPTANIP-----Q--R---K-
NLCFHQNEAK------------KGSLEVVSQTPGPQRAFP-PSASQCHCKHME-------
----------RWARGL-ASE--ESEVEKHKA----YQPDLYRSKTNNNT-V--EGEPAVI
PTEPFKLKHELLK-EPWKESTEGE--KSFPMY----VPEGSEPKP-EDMDFENKDD-YEK
DVTCHSQDYPGKYSEEESKSSTSGMAGDLGEEAQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGAL-PTPILTSSAGSRNSLSEPEATEHGFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQYSATHGHPPIVLNGWH
GESAIDLSCSSEGSP-GTTSPFPVSTSTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHIEGGMDLIFLKEQTLQAGILEVH------EDAGQA
TLST-THPEGPGAASPVSEPTTASGNQAEKAVPSKSLLDWLRQQA-DYSLDVPGFGASFS
DKPKQRRPRCKEPGKLDISSMSGEERVPTVPKEPGL------------------------
-----------RGFLPESKFNHTLTEPVLRD--AGP-RRRGRRPRNELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMATTCTTTASASLSSTTKSGTSATEKTTEDKLSGRDVKAD
TLVEDKPGPGTFS----DQSEPTITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQGRHSEMLGLESQKRKKKKTKGENP--------NPEPASGCEREPDSDQSCTESS-T
ALPPEREHVAQAGEGGLKDSNDDTN

--------------------------------------HKSKVQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVARHCLPQQDLYTTEE-----------EAXXXXX
XXXXXXXXXXXSGGGGTGVKKKRKKKEPGEQEGAAKGNKDREPKPKRKREPKEPKEPRKT
KELKKAKE---PKEPKQKEGAKKTRKPREASASVL--------------------LSTFR
PTPVERKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEVWPLHDDHRHHRKF

PF00385 // ENSGT00760000119067_8_Domain_0 (350, 412)

ILASKTIQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQ------
---PDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFESLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFNWYNSX-
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------XX

PF00176 // ENSGT00760000119067_8_Domain_3 (702, 772)

FLEPTQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYY

ENSGT00760000119067_8_Linker_3_4 (772, 857)

R--------
------------------------------------------------------------
----------------

PF00271 // ENSGT00760000119067_8_Domain_4 (857, 965)

LIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKCGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQKRKSMPSYLLYIASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGPVSNA----------
-----------VMKATIHNTVVLHLTILSLLHLDTYYGVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGVYFS---------LF
CLPF--------ER---------------YSICTTDKEDNAEDKLDGLQKQMNSSDG---
-------GEGLCGEKKDDSRPAQDSSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRAVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYNFVAMCRNVCRLPAWKDGGPPDATIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGGLCCLYQTNSKLYESLAYSQMSRTSE
SLESEPENLVKIESR-DDHLGLRGGSFPDVTCDNFISKVQDVISINHDESLLPXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXX--XXXX-XXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXLTPISKEREHCCDEAGQRPGSM-------GQLE-AKSIPS-
--TALDVGNESGFV--DMCSLSVC--DSKRNLSSDQKLMDLLENKSLESKLILSQNQSDE
EEEEDENE-----------GETLTVAAGTREKPEVLHLANPTANIPR-----------EK
SHGFHLDEAK------------KGSLEVVS-QTGPPRAFP-PASCQCHCKHME-------
----------RWAHGL-GSD--EFEVEKPKA----YKPDLYKSKANNT---TVEGEPTAI
PSEPFKVKPELLK-EPWKESAERK--KGFSTY----ASEGSEPKS-EDMDFENKDD-YER
DGTCHSQDYPGKYSEEESKSSASGIAGDFGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDSICHVVLKGKWPSSQ-QYEPSGTL-STAVLANSAGSRNSLSEPEAAEHSFSNG
ATLAAQVQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSATHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSANTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPTAAANGQAEKAIPSKSLLDWLRQQA-DYSLDVPGFGAVSV
CCNLQ-------------------------------------------------------
---HLMFLCPFQGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNAPMAATCTSTAPASLSSTTKGGIAATEKTTEDKPSSPDEKAD
TLAEDKPGPSPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMXXARHSEIAGLESQKRKKKKTKGDNPNP------NPEPAPGREREPGTDQNCTESS-T
PLPPEREHVAQSGEGGLKDANSDTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVTRHCLPQQDLYTTEE-----------EADTLFP
RKVTSCNGMEDSGGGGTGVKKKRKKKEPGEQEGAAKGNKDREPKPKRKREPKEPKEPRKA
KEPKKTRE---PKEPKQKDGAKKTRKPREASGTKEAKEKRSCADSTARTKSKKT-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 535)

SLQILPEIKHVDRPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFN

PF00176 // ENSGT00760000119067_8_Domain_2 (535, 811)

WYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDTQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPTQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKMK
NQLLLPELKNADWLTTCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGGTDGTSDIPERSNMDKEDNAEDKLDGLQKQTENSSDG--
-------GEGIFGEKKDDSQSAQDSSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPETLGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYNFVAMCQNVCRLPAWKDGGPPDATIYIEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYSQHKRTDTQAPDSLCCLYQTNSKLYESLTYTQMNRTSE
SLESEPENLVKIESR-DDHLGLPGGSFPDVTCDNFISKVQDVISINHDESLLPESLENMM
YGKKVLSREPGSFQEGPI--IN--TESRKDAVAMLASKNTSCRPSDREAEIAS-VS-VMD
SLEA-GVAQMNIKSGKSLLTPIS-KERERCCSEAGQRPESI-------RQLE-AKCLPS-
--PPLDSENESGFV--DMCSLSVC--DSKRNLSSDQKLIDLLENKSLENKLILSQNQSDE
EEEEEGENE----------EETLAMAAGTREKPEILHLTKPIANIP-----R--E---K-
NQGFHLDEAK------------KGSLEMVSQTPGPSRAFP-PASCQCHCKHME-------
----------RWLHDL-GND--EFEVEKSKA----YNPDLYKSKANNTT-V--EGEPTAI
PSEPFKVKPELFK-EPWKESTEGK--KGFSTY----APEGSEPKS-EDMDFENKDD-YDR
DGTCHSQDYPGKFSEEESKSSASGVAGDLGDDPQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDSICHVVLKGKWPSSQ-QYEPSGIL-STPVLANSAGSRNSLSEPEAAEHSFSSG
ATLAAQVQKESFLAPVFTKDEQKHRRPYDFEVER-DAKARSLEQFSATHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVNTNTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEAPGPTTSAPEPAAAASGQAEKAIPSKSLLDWLRQQA-DYSLDVPGFGANFS
DKPKQRRPRCKEPGKLDISSLSGKERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNTPLATTCTSTAPASLSSTTKSGTTAIEKTAEDKPSSHDVKAD
TLAEDKPGPSPFS----DQSEPTITASSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNP------NPEPAPSCKREPGRDQNCIESS-T
PLPPEREHVAQAGEGGLKDSNNDTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVTRHCLPQQDLYTTEE-----------EADTLFP
RKVTSCNGMEDSGGGGTGVKKKRKKKEPGEQEGAAKGNKDREPKPKRKREPKEPKEPRKA
KEPKKTRE---PKEPKQKDGAKKTRKPREASGTKEAKEKRSCADSTARTKSKKT-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 535)

SLQILPEIKHVDRPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFN

PF00176 // ENSGT00760000119067_8_Domain_2 (535, 811)

WYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDTQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPTQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKMK
NQLLLPELKNADWLTTCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGGTDGTSDIPERSNMDKEDNAEDKLDGLQKQTENSSDG--
-------GEGIFGEKKDDSQSAQDSSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPETLGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYNFVAMCQNVCRLPAWKDGGPPDATIYIEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYSQHKRTDTQAPDSLCCLYQTNSKLYESLTYTQMNRTSE
SLESEPENLVKIESR-DDHLGLPGGSFPDVTCDNFISKVQDVISINHDESLLPESLENMM
YGKKVLSREPGSFQEGPI--IN--TESRKDAVAMLASKNTSCRPSDREAEIAS-VS-VMD
SLEA-GVAQMNIKSGKSLLTPIS-KERERCCSEAGQRPESI-------RQLE-AKCLPS-
--PPLDSENESGFV--DMCSLSVC--DSKRNLSSDQKLIDLLENKSLENKLILSQNQSDE
EEEEEGENE----------EETLAMAAGTREKPEILHLTKPIANIP-----R--E---K-
NQGFHLDEAK------------KGSLEMVSQTPGPSRAFP-PASCQCHCKHME-------
----------RWLHDL-GND--EFEVEKSKA----YNPDLYKSKANNTT-V--EGEPTAI
PSEPFKVKPELFK-EPWKESTEGK--KGFSTY----APEGSEPKS-EDMDFENKDD-YDR
DGTCHSQDYPGKFSEEESKSSASGVAGDLGDDPQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDSICHVVLKGKWPSSQ-QYEPSGIL-STPVLANSAGSRNSLSEPEAAEHSFSSG
ATLAAQVQKESFLAPVFTKDEQKHRRPYDFEVER-DAKARSLEQFSATHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVNTNTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEAPGPTTSAPEPAAAASGQAEKAIPSKSLLDWLRQQA-DYSLDVPGFGANFS
DKPKQRRPRCKEPGKLDISSLSGKERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNTPLATTCTSTAPASLSSTTKSGTTAIEKTAEDKPSSHDVKAD
TLAEDKPGPSPFS----DQSEPTITASSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNP------NPEPAPSCKREPGRDQNCIESS-T
PLPPEREHVAQAGEGGLKDSNNDTN

---------------------------------MKMKIQKKEKQLSKLRALNHSPMSDAS
VNFDYKSPSPFDCSPDQGENI---EEAANHCLPHKDLYTTEE-----------EADTLFS
RKLTSHNGMEDSGGRGTGVKKKRKKKEPGEQEGT-KGSKDREPKPKRKREPKEPKEPRRA
KEPKRAKE---PKETKQKDGVKKPRKPREASGTKEGKEKRSCTDYGSRTKSKKA-SKEQG
PTPVERKKKGKRKNETTVESLELDQSLPNPSLQSPEEPSESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEVKHVERPASDAWQKLETSREYKNSNRLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSIAFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKAHSAEASDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLSDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWPLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSEIPERGNIDKEDSAEDKLDGLQKQTASPSDG--
-------SDGIFGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPESLGPCNQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRVISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDDGPPDASIYVEPITEER
AAKTLYRIELLRKVREQVLTCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAAGSLCCLYQSNSKLYESLTYTPMSRTSE
SLESEPENLIKMESR-DDHLCLPEGGLPDITCENFVSKVQEVISLDHDENLLPESLENMI
YGKTGLSQEPHSFQEAPN--TN--TQSRKNTITISASRNESCQPPDIEAEITSASS-LMS
SLEA-GVAKMNIKNGKHLLVSIS-KEGEPCCSETGRVPETV-------GHRE-AKCLAS-
--PTLDTGHESGFV--DLCSLSVY--DSKRNFSSDQQLIDLLENKSLESKLILNQSDE--
---EEEENE----------DETLAIVASTTEKPEVLDFPKPTANIP-----R--G---K-
NLSFHQDEAK------------KGKLEVVSKTAGPQRVFP-PPANQCHCKHIE-------
----------RWTHGL-GSE--ESEVEKPKA----YQPDLYRSKANNTT-V--EGEPAII
PTEPFKLKHELLK-EPWKESSEGG--KSFSMY----VPEGSEPKP-EDMDFENKDD-YEK
DGTCHSQDYPGKYSEEERKSSASGIAGDLGEEAQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPCSH-QYEPSGAL-PTPVLSSSAGSRGTLSEPDATEHSFSNG
AALAAQIQKENFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEEYSASHGRPPIVLNGWH
SESAIDLSCSSEESP-GTTSPFPASASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHIEGGMDLIFLKEQTLPAGILEAH------EDAGQT
TLST-THPEVPGAASSAPEPTAAASSQAEKAVPSKSLLDWLRQQA-DYSLDVPGFGTNFS
DKPKQRRPRCKEPGKLDISSLGGEERVPAVPKEPGL------------------------
-----------RGFLPESKFNHTLAEPVLRD--AGP-RRRGRRPRNELLKAPAIV-TDSP
SGMGPLFMNGLIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEEVKNTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMATTCTTTASASLAS-TKSGASATEKSTEDKLSGHDVSAD
TLVDDQPGPSPFS----DQSDPTITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEMVGLETQKRKKKKTKGDSP--------TQEPASVCEKEPGSDQNCTESS-A
TVSPEREHVAQAREEGLKDSNDDTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVPSHCLSQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGATKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKTRKPREASGTKEAKEKRSCADSAARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGAPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
TLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSKELGSFRESPS--TN--TESAKDVITISASKDGNCQPGGHEAEIASSPA-FMG
CLEAGGVAQANIKNGKHLLMSIS-KEGELCCSESGQRPESI-------GQLE-AKCLAS-
--SSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENFAMTAGMGERSEVLHLMEPTTDIS--------R---EK
SQGFHVDETK------------RGSLEAANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YNPDLFRSKTNTIA-M--EGEPTAV
PSELFKVKHELLK-EPWKESAEGQ--KVFPTY----PLEGSELKS-EDIDFENKDD-YER
DGNCHSQDYPGKYSEEESKSSTSGIAGDTGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDSICQVVLKGKWPSSQ-QYEPSGTL-PTPVLTSTAGSRTSLSEPEVAEHSFTNG
TALAAQIQKESFLAPVFTKDEQKHRRPYEFEVDR-DAKARGLEQFSATHGHTPIILNGWH
GESAIDLSCSSEGSP-GGTSPFSVSSSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPPTAASSQAEKAIPNKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFIPENKFNHTLAEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPSIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMATTCTSTAPVSLSSTTKSGTAVTEKTAEDKPSSHDVKTD
SLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVSLESQKRKKKKTKGDNPNS------HPEPAPSCQREPSSEQNCTEPS-A
PLPTEREHVAQAGEGALKDSNNDTN

---------------------------------MKMKIQKKEKQLSKLRALNHSPMSDAS
VNFDYKSPSPFDCSPDQGENI---EEAANHCLPHKNLYTTEE-----------EADTLFS
RKLTSHNGMEDSGGRGTGVKKKRKKKEPGEQEGT-KGSKDREPKPKRKREPKEPKEPRRA
KEPKRAKE---PKETKQKDGVKKPRKHREASGTKEGKEKRSCTDYGSRTKSKKA-SREQG
PTPVERKKKGKRKNETTVESLELDHSLPNPSLQSPEEPSESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEVKHVERPASDAWQKLETSREYRNSNRLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSIAFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKAHSSEASDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLSDRARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWPLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNIDKEDSAEDKLDGLQKQTASPSDG--
-------SDGIFGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
AFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDDGPPDASIYVEPITEER
AAKTLYRIELLRKVREQVLMCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGSLCCLYQSNSKLYESLTYTPVSRTSE
SLESEPENLMRMESR-DDHLCLPEGGLPDITCENFVSKVQEVISLDHDENLLPESLENMI
YGKTGLSQEPHSFQEAPT--TN--TQSRKNTITISASRNESCQPPGIEAEITSASS-LMS
SLEA-GVAKMNIKNGKHLLVSIS-KEGEPCCSETGRRPETI-------GHRE-AKCLVS-
--PTLDTGHESGFV--DLCSLSVY--DPKRNFSSDQQLIDLLENKSLESKLILNQSDE--
---EEEENE----------DETLAIVASATEKPEVLDFPKPTVNIP-----R--G---K-
NLSFHQDEAK------------KGRLEVVSKTAGPQRVFP-PPANQCHCKHIE-------
----------RWAHGL-GSE--DSEVEKPKA----YQPDLYRSKANNST-V--EGETAVI
PTEPFKLKHELLK-EPWKESSEGG--KSFSMY----APEGSEPKP-EDMDFENKDD-YEK
DGTCLSQDYPGKYSEEESKSSASGIAGDLGEEAQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPCSH-QYEPSGAL-PTPVLSSSAGSRSSLSEPEATEHGFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEEYSATHGRPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHIEGGMDLIFLKEQTLQAGILEVH------EDAGQT
TLST-THPEVPGATSSAPEPTAAASSQAEKAVPSKSLLDWLRQQA-DYSLDVPGFGTSFS
DKPKQRRPRCKEPGKLDISSLGGEERVPAVPKEPGL------------------------
-----------RGFLPESKFNHTLAEPVLRD--AGP-RRRGRRPRNELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEEVKNTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMATTCTTTASASLAS-TKSGTSATEKSTEDKLSGHDVNTD
ALVDDKPGPSPFS----DQSEPTITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEMVGLETQKRKKKKTKGDSP--------TQEPASVCEKEPGSDQNCTESS-A
TVSPEREHVAQAREEGLKDSNEDTN

------------------------------------------------------------
------------------------------------------------------------
------NGMQDSGG--TGVKKKRKKKDLGEQEGGDKAAVEVKPK--RRREPKEPKEPKKV
K------ESKKPKEPKQREVAKKPRKPREPKAPKESKDKKSGSEPAPRSRSKKS-SKD--
-TPVEKKKKGKRKNEIPVNSLDLDQDLPSPSVQSPEESAESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASRMVQKEA
H----PGGLAFETEEFYVKYRNFSYLHCKWATL-EELEKDPRISQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 486)

EVDRILEVAHTKDPDTGEEVTHYLVKWCSLPYEESTWELEEDVDPG
KIKEF

ENSGT00760000119067_8_Linker_1_2 (486, 536)

EALQIPPEIKHMERPASESWQKLEKSREYKNSNQLREYQLEGMNWLLFNW

PF00270 // ENSGT00760000119067_8_Domain_2 (536, 667)

YNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDTQGNPLPGIFKFQVVITTFEMILADCPELKKIQWRCVVIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPQQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLSKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHCPEAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNEKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDDKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPEIKNADWLATCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKAEVLGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWNAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKLLSAEQGISDGAQDATERGIMEKEENSGEKLEGLDGHM--------
--APTDDCD---RSCSPWKAEAQDGSDSDRSCWPVSSALTARLRRLVTVYQRCNRKELPP
RTEMLVPGNHGYWLQDEMFRRASEMDLMNKEMQKRWTRREQADFYRTVSSFGIIYDQEKK
IFDWAQFRAISRLEKKTDESLEKYFYSFVAMCKNVCGLPLWKEDGPPDPDIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLKLCQPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTGLPGPETLCCLYQSNSKLYSSPVYSQMDQSCE
TLENEAESHIKLEPV-DSTMSQAGGSPLDTHCETFMSEVRDIISSNYDESSLPDSLVCMM
YDEKTCPSEQSSLTRDSPSCTD---VGSSVAKLSEGKLEGDEDPSSCDADAMREVP-FLE
GLQV-VSDQMDNQNEEAEPSPST----------PDSNPSQSAPSKLSKGLEQ-KGALASP
ATGLPEHGTMERVLSVGLYSPSLH--NYELK----QRFISLLQEKGLKAKSGPSQSHSEE
D----EEEEEDDDNS----EAAADAEEGLNGSRT-RADFDPEAHELGG------E---EQ
SSGLPTPEDTCPEDLNGERES---------LGLGEPGAEV-REDCGLN------------
------------------EE--STQQHSPGQ----AQSQPFSLP--AP---LPQGGPLGA
EAPCA---------------------EGQTGCTETLHPEPQGIKQ-EECEN---RDDGEK
ASSNQSQDGPEKYLEEENKNSASVLPGEI-DDLQDARAPTIAQLLQEKTLYSFSEWPKDR
VIINRIDNICHAILKGKWPSSSQQFEAQSLL-TAPAMASNTGSRSSFTESEAPDPTFNNG
V-LMSRVQKEGFLSPTFAKDERKHRRPYEFEMER-DAKQRSLEQLAAAHVHPPIVLNGWR
E-AAVDLSRGSDGSP-GNSSPFPLNTNVPKLGTVN--ALQSSLGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKNVE-GMDLIFLKERPLPNRLQ-DV-----QEDQPQP
PQNS-PLPDGPVAATSTPQPVPAAGSQE-KAVPNKSLLDWLRQQS-DYTLDVPSFGTNFS
DKPKQRRQRCKDPNKLDIS

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2675)

SLTGEERVPVVHKGTGRR-----------------------
------------GYLPENKFNRILSEPVLRD--TGP-RRRGRRPRNELLKGPGVV-ADSS
SGMGPLFMNGLIAGMDLVGLQNMRNMQGIPLTGLVGFPAGFAAVPSGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLNSPMTTTCTATAPTSLTSTTKGGTASTEKANEEKQGSQDGKRE
PLTEDKPGPSSFS----NQTESAITTSSPVAFNPFLIPGMSPGLIYPSMFLSPGIGMALP
GIQQTRHSEAANLETQKRKRKKAKGELANP------EPETVSLPEKEAANSQNCAQQS-L
SVVAEKEQDGPAEEE----------

---------------------------------ASCTFKKQKEQLPHFEVLSDSPMSDVS
ITFECKPQSLFADNTDQDDLH---DLVTISDLASVSLTQKEQ----QDVLPVEIPNEILQ
TMVTSHNGMEDIGGGGIGVKKKRKKKELNQQEPG----SEKESKPKRKREPKEPKEPKKP
KEPKK------PKEPKQ-EGVKKPRKPRESKVPKEPKEKKSNLESPPKAKPKKASSTEQG
PTPVEKKKKGKRKSDTPVDSLELDQSLLSISGQSTEESAESVDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRASALSASTLAWQAEEPPEDDAN--IIEKILASRMFQKEV
QGSWWPGSPEYYLSKHMTKYCVLSL-KCSTKVMEHNLLLFPDLSAEMGRGNTKQSLPYHA
VCSADSASLLPEKKERNAIILLRHNCQGDIA

PF00385 // ENSGT00760000119067_8_Domain_1 (452, 486)

QEVTHYLVKWCSLPYEESTWELEEDVDPG
KIKEF

ENSGT00760000119067_8_Linker_1_2 (486, 519)

EALQILPEIKSLERPASESWQKLEKSRGYKNNN

PF04851 // ENSGT00760000119067_8_Domain_2 (519, 688)

QLREYQLEGMNWLLFNWYNMKN
CILADEMGLGKTIQSITFLFEIYLMGLRGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIHQYEMVYRDAQGNPLPGVFKFHVVITTFEMILADCPELKKIQWRCVIIDEAH
RLKNRNCKLLEGLKLMCLEHKVLLTGTPLQNSVEELFSLLNFLEPQQFPSETAFLEEFGD
LKTEEQVKKLQSLLKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLSKGANQHNMPNLINTMMELRKCCNHPYLINGPGAEEKILEDFRKTHSPDALDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQTEGKGST--FSKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLSERTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQLLPPEFKNADWLTTCNPEIVLHDDSYKKHLKQHCNNIVSRAREIILSLSSALLGKEKI
EGAYDG--HIDLDVLLPDIDYVEVPIDWWNADADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEMLLSADQSVVDGVQDAPERGNVDKEENSADKLDGEQKQEETSDSC--
---------GEVAEKKDDNVAAQDGPDPDKSSWPVSSALTARLRRLVTVYQRCNRKELPS
RPEIMGTCNHGYWLQEEMFRRANEMDSINKEMQKRWTRREQADFYRTVSSFGVVFDPEKK
VFDWAQFRSISRLEKKTDESLEKYFHSFVAMCRNVCRLPHWKDDGPVDTSVYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLKLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTGVIGAENLCCHHQANAKLYCSPAYNQMENKHA
SVETEAESCIKLMNSGSSLLQ------TDGSCENI--KIQGMISLNYDESSLPDSLVCMM
YDEKACNSEHSSLARDSPSCTD--ISSNT-TKMADSKIDGDEDLSSCDAEATREP--YLD
HLQF-GSDQMEGQNAPQEPSV---KETKLAE---------SFPVESCNNLQHLDSQYDSP
GSVPFERDGIERVLSIGVYSPSLP--NFDIKVHPEKRFMGMLHEKGLEEKSVQSQSHSEE
EEEEEEEEDYDHLET------AADTVQDLRSCLKTLDGGKVECNMEEVQKHG--SCIFST
LDAFMVERNK-------------ELVESIS---------SEQAASKCDSEPGV-----GE
DDQA-------------ECE--SLEEHIPAIPDIQTCPHHYQHSAR--------NQASVI
QMELLKSHPVCMEADPWGDDTEEK--RDGPIS-------QNEMKREEGCEN---QDLEKK
DEITQNQDCLEKFSEDESKSSICVAPGEI-DELQDVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRIENICHAILKGKWPCSSQPYEVQSMV-PTPALTTNSGNRSSYTEPETPEPCFSNG
M-TTTQAPKDGFLAPTFVKDEPKNQQPYKFEMER-DAKPQSLEQLVASHPHPSIVLNGWR
D-AAVDLSRVSDGSP-ASSSPFSLSTSIPKLGTVS--ALQGSLGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKNVE-GIDLIFLKDRSPQTGLSIIQ------EDQTPT
V-QSNPNPDEPAVTTSSQQTVPSTNVEEEKIIPNKSLLDWLRQQS-DYTLEIPGFGTSFS
EKPKQRRQRCKDPSKLDIH

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2678)

SLTGEERVPVVHKGTGR------------------------
-----------RGFLPESKFNRILTEPVLRD--AGP-RRRGRRPRSEVFKTPGII-ADAS
SGMGPLFMNGLIAGMDLVGLQNMRNMQGIPLAGLVGFPAGFAAVPAGEDVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPSMTTTCASPASNSLASTAKSGTSHADKDTEDKQSDQGAKPE
TISEDKSSPSSFS----DQSEPAITTSSPVAFNPFLIPGMSSGLLYPSMFLSPGIGMALP
GLQQTRHLEATNVENQKRKRKKTKVELANP------EPETLSLSDKEHANNQNCREQTYV
--SAEKESNIPAEEEEELKEDKDIN

-------------------------------------------QLAKLKALNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVANHCLPQKDLYTTEE-----------ESDTFFS
RKLMSHNGMEDSGGRGTGVKKKRKKKDPGEQEGT-KGSKDREPKPKRKREPKEPKEPRKA
KEPKRAKE---PKEAKQKDGVKKPRKLREASGIKEAKEKRSCTDYVSRTNSKKA-SKEQG
PTPVERKKKGKRKNETTVESLELDQSLPNPSLRSPEEPTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEVKHVERPASDAWQKLETSREYKNSNRLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKAHSSEASDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 960)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQVTIR
MIALYVSCLDS-------------------------------------------------
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--------------------------------M-EELEKDPRIAQKIKRFRNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRPSTGS
VSQTQTALSFFCVPEREAWGLISRLLIPASYLILTGTHKMTCR-----------------
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--------MYSN------------LIALFVCSSEGVMCLFSLSQLAKLKALNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVTNHCLPQKDLYTTEE-----------ESDTFFS
RKLISHNGMEDSGGRGTGVKKKRKKKDLGEQEGT-KGSKDREPKPKRKREPKEPKEPRRA
KEPKRVKE---PKEAKQKDGVKKPRKAREASGIKEAKEKRSCTDYVSRAKSKKA-SKEQG
PTPVERKKKGKRKNETTVESLELDQNLPNPSLRSPEEPIESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFESLQILPEVKHVERPASDAWQKLETSREYKNSNRLREYQLEGMNWLLFNWYNSKA
VKV---------------------------------------------------------
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------------YRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELEVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNIDKEDSAEDKLDGLQKQTASPSDG--
-------SDGIFGEKKDDSQAAQDGSNPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEVFRRSSEMDLISKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRSVCRLPTWKDDGPSDTSIYVEPITEER
AAKTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQPPGSLCCLYQTNSKLYESLTYTQMSRTSE
SLESEPENLVKMERR-DDPLCLPEGSLSDITCENFISKVQEVISIDHDESLLPESFENMM
YGKTGLSQEPCSFQETPS--TN--TQSRKDTVTISVNRDKSCQPASTEAEVTSGSS-LMS
SLEA-GVAKMNIKNGKHLLISIS-KEGEPCCSETGRRPESM-------GHLE-AKCLAS-
--PTLDTGHESGFV--DLCSLSVC--DSRRKLSSDQQLIDLLENRSLESQLILSQNQSDE
EEE---END----------DETLAIVASTVEKPESLHFTKPTANIP-----K--G---K-
NLCFHQDEAK------------KGSLEVVSQTPGPQRAFP-PSVSQCHCKHME-------
----------RWARGL-GSE--ESGIEKHKA----YPPDLYRSKANSIT-V--EGEPAII
PTEPFKLKHELLK-EPWKESTEGG--KSFPVY----VPERSEPKP-EDMDFENKDD-YEK
DGTCHSQDYPGKYSEEESKSSTSGMAGDLGEEAQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGAL-PAPVLNSSAGSRNSLSEPEAAEHGFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKTRSLEQYSATHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSTSTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHIEGGMDLIFLKEQTLQAGILEVH------EDAGQA
TLST-THSEGPGAASPASEPTAASSNQAEKAVPSKSLLDWLRQQA-DYSLDVPGFGASFS
DKPKQRRPRCKEPGKLDISSLSGEERVPAVPKEPGL------------------------
-----------RGFLPESKFNHTLAEPVLRD--AGP-RRRGRRPRNELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMATTCTTTASASLSSTTKSGASATEKTTEDKLSGRDVKAD
TLVEDKPGPGPFS----DQSEPTITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMTLP
AMQQGRHSEMVSLESQKRKKKKTKGDNT--------NPEPASGCEREPDSDQNCTEST-T
SLPPEREHVAQAGEGGLKDSNDDTN

-------------------------------MFFKVQKLFILISLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGVKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDIISINHDESLLPESLESMM
YGKKVLSQEPGSFRESPS--TN--TECRKDVITISISKDGNCQPGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEEDLCFSEAGQRPESI-------SQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTIDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTSTIA-M--EGEPTAV
ASEPFKVKHELLK-EPWKEGAEGQ--KVFPTY----PLEGSELKA-EDMDFENKDE-YDR
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSVGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPSFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAGDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDENCAEPS-A
LLPAEREHVAQAGEEALKDSNNDTN

------------------------------------------------KALNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVANHCLPQKDLYTTEE-----------EADSLFS
RKLISHNGMEDSGGRGTAVKKKRKKKDPGEQEGT-KGSKDREPKPKRKREPKEPKESRRA
KEPKRAKE---PKEAKQKDGVKKPRKPREALGSKEAKEKRSCADYVSRTKSKKA-SKEQG
PTPVERKKKGKRKNETTVESLELDQSLLNPSLRSPEEPAESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQILPEVKHVERPASDAWQKLETSREYKNSNRLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKAHSSDTSDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 959)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQVTIR
MFALYVSCPDSQNVITKSGLVIGCLLCFV-----LWHRHLK-IWPGEETN----------
------------------------------------------------------------
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MNGRMECLKFSNLVIVNFFFVLCLAEITFIPDLMIMKIQKKEKQPPSLKALSLSPMS---
SAWECKGQDTFASSEEQDEVP---HQVTVTATSTGGQCQCP----------KEESDGAPP
KRTSTQNGMQDSGG--MGVKKKRKKKDLGEQEGGDKAAVEVKPK--RRREPKEPKEPKKV
K------ESKKPKEPKQREVAKKPRKPREPKAPKEPKDKKSGSEPAPRSRPKKS-SKD--
-TPVEKKKKGKRKNEIPVNSLDLDQDLLSPSVQSPEESAESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASRMVQKEA
H----PGGLAFETEEFYVKYRNFSYLHCKWATL-EELEKDPRISQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 486)

EVDRILEVAHTKDPDTGEEVTHYLVKWCSLPYEESTWELEEDVDPG
KIKEF

ENSGT00760000119067_8_Linker_1_2 (486, 519)

EALQIPPEIKHTERPASESWQKLEKSREYKNSN

PF04851 // ENSGT00760000119067_8_Domain_2 (519, 688)

QLREYQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDTQGNPLPGIFKFQVVITTFEMILADCPELKKIQWRCVVIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPQQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLSKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKAHCPEAADFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRFNEKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPEIKNADWLATCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKAEVLGE-AA
DKAFEGTPARELDVLLPDIDYVEIPVDWWNAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKLLSAEQGVSDGAQDAAERGSVEKEESSGEKLEGLSKQE--------
--DIVAAGVGEASEKRDEPATAQDGSDSDRSCWPVSSALTARLRRLVTVYQRCNRKELPA
RGEVLVPGSHGYWLQDEVFRRASEMDSLNREMQKRWTRREQADFYRTVSSFGVIYDQEKK
IFDWAQFRAISRLEKKTDESLEKYFYSFVAMCKNVCGLPLWKEDGAPDPDIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LQERLKLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRAGFPGPETLCCLYQSNSKLYSSPVYSRMDQSCE
TLENEGESHVKLEAV-DSAMCQAGGSPLDANCDTFMSEVRDIISSNYDESSLPESLVCMM
YDEKACPSEQSSLARDSPGRTD---GGSGIAKLSEGKLEGDEDPSSCDADAMREAS-FLE
GLQV-GSDRMDNQNEEAEPSPPT----------PKGNPSQSALVKLGKGLEQ-KEALASP
AAGLPEHGTMERVLGVGLYSPSLH--NYELKVPPEQRFISLLQEKGLEAKLGPSQSHSEE
D----EEEEEDDDNS----EAAADAMEGLNGSRT-RADCDTEAHELGG------E---EQ
SSGLPTPEDTCPEDVNGERES---------LGLGEPRAEG-REDCGLN------------
------------------EE--STQQLPPGQ----AQSQPFGLP--TP---LPQGEPRGE
EPPCV------RG-EPLGR---DA--EGQTGCTEAPHPEPQGIKQ-EECEN---RDDGDK
ASSNQSQDGPEKYLEEENKNSASVLPGEI-DDLHDARAPTIAQLLQEKTLYSFSEWPKDR
VIINRIDNICHAILKGKWPSSSQQFESQSLL-TAPAMASSTGSRSSFTEPEAPDPSFNNG
V-LMSRVQKEGFLSPAFAKDERKHRRPYEFEMDR-DAKQRSLEQLAAAHVHPPIVLNGWR
E-AAVDLSRASDGSP-GNSSPFPLNTNMPKLGTVN--ALQSSLGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKNVE-GMDLIFLKERPLPNRLQQDV-----QEDQPQP
PQNS-PLPDGPVAATSTPQPVPAAGSQE-KAVPNKSLLDWLRQQS-DYSLDVPSFGTSFS
DKPKQRRQRCKDPNKLDIS

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2645)

SLTGEERVPVVHKGTGRRLGGATAPALKELPRWLDANLEYA
VAADWADIVKLSGYLPENKFNRVLTEPVLRD--TGP-RRRGRRPRSDLLKGPGVV-ADSS
SGMGPLFMNGLIAGMDLVGLQNMRNMQGIPLTGLVGFPAGFAAVPAGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLNSPMATTCTATAPTSLASTTKGGAASAEKAGEEKQG-QDGKKE
PLAEDKPGPSSFS----NQTESAITTSSPVAFNPFLIPGMSPGLIYPSMFLSPGIGMALP
GIQQTRHSEAANLESQKRKRKKAKGELANP------EPETVSLPEKEAANSQNCVEQS-P
PAAAEKEQDGPADEERQAAHDTD--

-------------------------------MKMKI--QKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGVKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 848)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKL

PF00271 // ENSGT00760000119067_8_Domain_4 (848, 965)

VLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPGSFRESPS--TN--TECRKDVITISISKDGNCQPGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEEDLCFSEAGQRPESI-------SQLE-AKCLAS-
--SSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTIDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTSTIA-M--EGEPTAV
ASEPFKVKHELLK-EPWKEGAEGQ--KVFPTY----PLEGSELKA-EDMDFENKDE-YDR
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSVGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTARDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDENCAEPS-A
LLPAEREHVAQAGEGAPKDSNDDTN

---------------------------------MIMKIQKPDQQLPSLKALSYSPMSSAS
IPCEHPILPSFSESTPQDFHSVTLLDTTSHLLDDNVLYPDS------------GQEECLA
VEATSINGMENSGGGGTGVKKKRKKKEPGEEK---------VAKPKKKKEPKKVKEPKKV
KEPSEAKDPKEQKQPKSPKEPKKPRKP---REPKPPKQKKANQDSAAKTKPKKL-SKEQG
PTPLEKKKKGKRKAEFSEESLDGEPSLLNPASQSTEESTESLDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRASALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIERILSSRISQKEF
V----HAGIPLEVEEFYVKYRNFSYLHCKWATL-EELEKDPRIQQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

KQAQMKHI
FTEPDEDMFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRVLEVAHTKDSDTGEEVTHFLVKWCSLPYEESTWELEEDVDPV
KVKEFEA

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQKVPDLTPMERPASETWQKLVSSRTYKNNNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 875)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFFMGIRGPFLIIAPLSTITNWEREFRTWTEMNTIVYHG
SQISRQMIHQYEMYYRDEQGTPIPGIYKFQIVITTFEMILADCPELKKIRWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELYSLLNFLEPVQFPSESTFLEEFGD
LKTEEQVRKFYWLFDFLWMLD--------------------------------PEANDAS
FLTKGANQHNDLGKLYTMQPILLILGVLLFI----------RYFEHQSGPDL--------
----GKLY--------------------TMKPIL

ENSGT00760000119067_8_Linker_2_4 (875, 881)

LILGVL

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

LFISQKYIYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGNTNGVQPLSKIEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQSEGKGST--FAKASFVSSG
NRTDISLDDPNFWQKWAKIAELDTDARNEKESLVLDRPRVRKQTKHYNSFEDDELMEFSE
LESDTEERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILNLGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGHNQALQNHSGLSAPVPRGRKGKKLK
NQMLLPEIKNADWLASCNPEIVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKAEVLGE-AA
SRALEGENARDLEVLLPDIDYVEIPVDWWDTEADKSLLLGVYKHGYERYFAMRAD--PAL
CFLD--KVGMPDETSLTAD-GVNDVAPELGD-GSAIKEENNEEKVNEQQEDAS-------
------ESTGKEEKADEESSIAQDSPEADKLSWPVASALTARLRRLITVYQRCNRRD-LA
RPEVLVPTNHSYWLQEEMARR-AEMDPIMKEMQKRWTRREQADFYRTVSSFGVIYDPEKK
CFDWTQFRALSRLDKKTDESLEKYFHSFVAMCRNVCRLPLRKDDGSADPSLFLDPITEER
AARTLYRIELLRKVREQVLRHPQ-LHDRLKLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
SRTDYYIMNDPQLSFLDAYRNYAQNKRNS---GENMCYHFQMNSKVQETPSC-HLERTCE
STKLKPEKDIKTEVE-EATTSNQMCSPPDLTCENFISQVGDMISNNHDECSMSDSLMCMI
CDEKTCNSALLDASNSEQSSLTQNKAKEDNILPVEESVSRDCFLGSSEKDEPIQTAEQSL
GLD---LEFLDKTFGDHSALS-PGINEDKDCGITGEHSEGPHLN---------------P
--MPVQEKEEWGADLQELKEDPIVKWQNELNDMKDPPLEDVIKDHKLEDLSIEKV-----
-------NECLDM-----KHKTSLMLSGLLKQ----KVEDLKERIAGENVLEESNVPLEE
NETIKLEECEVKK---------------------EVK--KESVEEECNCKEFLIFY----
-------------RSS------ASRHMKANLLLSPFDPDIYKAREGCWK---------GV
VLHAVSIHPSLMI-SPQRASNELGRRFYYDMYSGSSSPAPLYIYIVFDHFNHMTPSSYDA
EGICLCVDYLDKYTEDDVKACPLSVPEESHQDFQDGRAPTIAQLLQEKTLYSFSEWPKDR
VIINRIDNICHAVLKGKWPSSSQQFEAQCMV-PSSVLSTC--TRSSSYPAEAQSIAYSNG
S-PVPQAQKEPLSAATFPNEERKHRRPFEFDSERQDGKLRGLEHLSPSHGRTNSALNGWR
D-AAIELCR--EQAA-GGGSSYPMNTSTPKIAGIG--GLQSSLGMDLSGILQAGLIHPVT
GQIVNGSLRRDESSL-RRRRGRRKNVE-GMDLGFLKDRGMHAGILGLREV------PNQL
GS---G-HTESSLSASARSGVPGAKFQPEKVISNKSLLEWLRQQS-DCTIDIPTYGGSFS
DKPKPRRQRCKEPSKPEFSLLAGDDRVSLVNKDTGQ------------------------
-----------QGFLPESKFGRALPEPLMHE--TMP-RRRGRRPRSELLKSTGTMGSDSS
SGMGPLFMNGLIAGMDIVGLQNMRNMQGIPLTGLVGFPAGFTAVSTNEEMKSTLSMLPMM
LPGMAAMPQMFGVGGIINSPMATS----VPTSLGSTIKSGSSHPDKATEDKDACPETKPD
TAPSDKPSGS-FQ----EKSEPAVTTSSPVAFNPFLIPGMSPSLLYPSMFLSPGIGMAIP
GVQPNRLSESGGIDHQRRRRKKTKGETQTS------EQETVPF--TESTETQNCDTDNTP
APENDKE------DSGLKDTLEPTD

---------------------------------MIMKIQKKEKQLSNLKDLNHSPMSDAS
VNFDYKSPSPCDGSTDQKEKT---EDVASHCLPXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX--XXXXXXXX-X-XXXXXXXXXXXXXXXXX--XXX-XXXXXXXXXX
X------XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XKEQG
PTPVEKKKKGKRKSESTVESLELDQGLPTPSLRSAEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEXXXXXXXX--XXX-XXXXXXXXXXV
H----PGEPPFDLELFYVKYRNXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQVLPEIKHVERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLLSVRTLFY-LKAEITGE-AA
DKALEGTPAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGTADGGADIPERXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX---XXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWTRREQADFCRAVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWMDGXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXXXXXXXXXX
X--XXXXXXXXXXXX-XXXXXX--X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
XXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXX-XXXXXXXXXXXXXXXXXX-XX-------XXXXXXXXXXX----XXXX-XXXXXXX
X-XXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X---XXXXXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX------X----X
XXXXXXXXXXXXXXXXXXXXX-X---XXXXXXXXXXXXXX-XXXXXXXXXXXX-------
---------XXXXXXX-XXX--XXXXXXXXX----XXXXXXXXXX-XX---XXXXXXXXX
XXXXXXXX---XX-XXXXX---XX--XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXYPGKYSEEESKSSASGITGD-GDDPQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PAPALTSSAGSRSSLSEPEASEHGFSGG
AAVASQVPKENFLSPGFTKEEQKHRRPYEFEVDR-DAKGRSLEQFSATHGHPPIILNGWH
GESAIDLSCTSEGSP-GGTSPFPVSASTPKIGAVS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAL-RRRRGRRRHVEGGMDLILLKEQTLQAGILEVH------EDPAQA
PLSA-SHAEGPVPAAEPACPSPAEK-----RSSSMDLQQYF---------FGALFGANFS
DKPKQRRPRCKEPGKLDVSSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHSLPEPALRD--AGP-RRRGRRPRSELLKAPAMV-ADSA
SGMGPLFMNGLIAGMDLVALQNMRNMPGIPLTGLVGFPAGFAAMPTGEEVKSNLSMLPMM
LPGMAAVPQMFGVGGLLNAPMAPTCSSAAAAPLSSTTKSGTAASQKAAEDKPASHDVSTD
ALAQNKLGPWPFSDL---FVNPVIPTSNPVAFN---------------------------
------------------------------------------------------------
-------------------------

-------------------------------MFFKVQKLLILISLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 455)

NKQAQMKHI
FTEVKQYLL-------------THLTAAFLAAEV

PF00385 // ENSGT00760000119067_8_Domain_1 (455, 487)

THYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGSPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYTAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNADKEDNAEDKVDGLQKQTESSSDG--
-------GDGVFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTFTQMSRTSE
SLENEPENLVKVENR-DDHLSL-----PDMTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPRSFRESPS--TN--IESRKDVITISISKDGNCQPGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEGELCCSEAGQRPESI-------GQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EE--EEENE----------EENLAMAVGMGERPEVLHLTEPTTDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTNTIT-M--EGEPTAI
PSEPFKVKHELLK-EPWKESAEGQ--KVFPTY----PLEGSEPKS-EDVDFENKDD-YDR
DGNCHSQDYPGKYSEEESKSSTSGITGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSH-QYEPSGTL-PTPVLTSSASSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEAER-DAQSRGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKSVPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDISSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPILRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTSTSTAPASLSAH--------KSTVEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSGDENCAEPS-A
PLPTEKEHGAQAGEGALKDSNNDTN

-------------------------------MKMKI--QKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGVKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLMNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 523)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 809)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHP

ENSGT00760000119067_8_Linker_2_4 (809, 881)

YLING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGSQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTISVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISISHDESLLPESLESMM
YGKKVLSQEPGSFRESPS--TN--TECRKDVITISISKDGNCQPGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEEDLCFSEAGQRPESI-------SQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTIDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCNHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTNTIA-M--EGEPTAV
PSEPFKVKHELLK-EPWKEIAEGQ--KVFPTY----PLEGSELKA-EDMDFENKDE-YDR
DGNCHSQDYLGKYSEEESKSSTSGITGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSDTL-PTPVLTSSVGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVS

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2675)

SLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAGDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDENCAEPS-A
LLPAEREHVAQAGEGALKDSNNDTN

---------------------------------MIMKIQKKEKQLSHLKVLNHSPMSDAS
VTFDYKSPSPFDHSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAETLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPGEQEGAAKGRKDREPKPKRKREPREPKEPRKA
KEPRRAKE---PKDPKQKDGAKKARKPREASGTKEAKEKRSGADSTARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRASALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

KQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQVLPEIKHMERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGVHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSSDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGQGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVLDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERSNTDKDDNTEDKLDGLQKQVESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRHVCRLPPWKDGGPPDPTICVEPITEER
AARTLYRIELLRKVREQVLTCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYVMTDPQLSFLDAYRNYAQHKRPDSQAPESLYCLYPTNSKLYESPTYTQMSRTSE
SLETEPENLGQIEGR-DDHLGPPGGSLSDITCENFISKVQDVISITHEESLLPESLESMM
YGKKGLSREPGSFQESPH--TN--TESRTDALGISASRGANCRPNGHEAEVAAGPS-LMD
SLEA-GVAQMNIKNGEHLLMSLA-RDKELCCNEAKQRPESV-------GQLE-AKFLAS-
--PSLDQGNESGFV--DMCNLSVC--DSKRNLSSEQQLIDLLENKSLETDLILNQNHSDE
EEEE-EENE----------EENLDVAAGGRGRPEVLPLSEPT------ASTP--G---EK
GRGLHAEEAQ------------KGRLGAGSRSAGLQGAFP-QVACQCHCKHLE-------
----------RWTRGL-ESD--EFEVEKPKG----HSPDLYKSKTNNIT-M--EGELTAI
PLEPFKVKHELVK-EPWKESAEGK--KGFPMY----PPEGSELKS-EDMDFESKDD-YDR
DGNCHSQDYPGKYSEEESKSSTSGLTGDIGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLNGKWPSSQ-QYEPSGTL-PAPVLTSTAGSRSSLSEPEASEHSFSNG
AALVAQIQKDSFLAPVFAKDEQKHRRPYEFEVER-DAKARNLEQFSATHGHPPIILNGWH
GESAIDLSCTSEGSP-GATSPFPVSASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAA-RRRRGRRKHAEGGMDLIFLKEQTLQAGILEVH------EDSGQA
SLSTSH-PEGPVPAPSTPEPAPAAGSQAEKTIPSKSLLDWLRQQA-DYSLDVPGFGATFS
DKPKQRRPRCKEPGKLDVNSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVSAAPKEPGL------------------------
-----------RGFLPENKFNHTLTEPVLRD--AGP-RRRGRRPRSELLKAPAIA-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATMPQMFGVGGLLNAPMATTCTSTAPAPLSSTTKSGTSVTEQTAEDKPSSRDGKTD
MSAEDKPGPSPYS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPPMFLSPGMGMALP
AMQQARHSEIAGLESQKRKKKKTKGDNPNP------NPEPAPGSDREPGNDQNCPESR-A
PVPSDREHAAQAGDGGLKDSNSDTN

----------------MNFSLVCFAEAGFFLRLLIMKIQKKEKQLPNLKVLSCSPMSDVS
VPCEYNPQSPFASSTDQEEKI---TDLASHCLTQKDLFPEEEDEEKEEDEEEAEANTLFP
KKMTSHNGTEDSWGGGTGVKKKRKKKDSGEQEGGEKGAKDRDPK--PKR-KREPKEPRKA
R------EPKKPKEPKQKEAVKRSRKPRESKVSKDPKDKRSSTEAAPKMRSKKT-SKEQG
PTPVEKKKKGKRKNETSVESLELDQGLLSPSLQNMEE---SADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEVTE--HDM--II

PF00385 // ENSGT00760000119067_8_Domain_0 (348, 412)

KNIMAGKMVQKGV
H----PGGLPFDMELFYVKYRNFSYLHCKWATM-EELEKDPRISQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDSDTGEEVTHYLVKWCSLPYEESTWELEEDVDPV
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 536)

SLQILPEIKHVERPASESWQKLEKSREYKNSNQLREYQLEGMNWLLFNW

PF00270 // ENSGT00760000119067_8_Domain_2 (536, 667)

YNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGIFKFHVVITTFEMILADCPELKKIQWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPLQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLAKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDALDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVHVLSAL-PVYK

PF00271 // ENSGT00760000119067_8_Domain_4 (883, 965)

TRRTYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDAKNEKESLVLDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDEKPTRSRRLNEKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPEIKNADWLTSCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKAEVLGE-VA
DKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGAQDVAERSSTDKEESSEDKLDGLQKHSESSSS---
---------CGEFEKKDDPTAAQDGSDPDKSPWPVASALTARLRRLVTVYQRCTRKE-PT
RPEVLVPGSQGYWLQEEMFRRASELDPVSKEIQKRWTRREQADFYRTVSSFGVVYDQEKK
SFDWTQFRLISRLDKKTDESLEKYFYSFVAMCRNVCRLPTWKDDGPPDPGIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LAERLKLCRPSLYLPVWWECGKHDWDLLVGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTGAQGPESLCCLYQSNSKLYESLTYHPMERIRD
PMENEPGNPVTADGT-DDRLGHPEDSPPDGTCEHLISRVQDIISIHPGEGLSPGA-----
YGETAFGGEPGSLVRETRGNAE--TEREAVAGLGSGALEDG--PGVWVARATGD-S-CFL
GLEA-GGERSNSKDEWQVPRSSPGKERTLDENAPTQRPDPKRPP-------E-AKRISRR
TPPPRDHGSLSGLVE--ICSLSVC--NSERKLPSEQQFIDLLEDKGLGGTLVLGQSPSDD
EDDEDEEEEEDEEEEEEEETGAAALRERLRGRPEVAKPTDPNAPAPGG------P-----
----------HGGAVGEEAAAKGSDPEQTNGGPGEPRCVG-RAASECHRQPIDRGKAEGG
TDESEGESPRDWDRGR-HKG--KALDNITTQ----G--GAA----------AVPSEPLNT
DLRLF------PE-DPWEA---SA---GRKPRRTASPPAGSELKQ-EDVESESRDDGEEK
DGSCLSQDFPGKYLEEESKSSTSGIAGDIGDDFNDGRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHAVLKGKWPSSTQQYEPPSTL-PAPVIMSGGAVRNSLPDPKAPNPGFSNG
T-LVAQIQKESFLAPMFTKEEQKPRRPYEFELDR-DAKSRSLEPFPTPHAHQPVVLNGWR
GETALDLSCTQDGSP-GPPPPFPGTTSTPKIGAVG--TLPGSLGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAS-RRRRGRRKNVEGGMDLIFLKERSLQAGILVGTPFSPSKEHHPPP
PHQW-HLSGA-------------------HRVAIRSLIQFPKPLR-PLER--NSPFLNFP
STPSQRRFEKLVPGGGTGSSSSSSSEIPILQ--LRD------------------------
-----------SGLVPDLKDSRVLSGEPYPASLVPE-VSKGPQPHSKVVKPPSQS-SQ--
--M-IIFLPNP------------KASTPSESSSTSQLPSHFRPPPSPGNTVQPRRSFSVP
FMGSSSVSQPFWVPF-----YSPSASAPSENSFAPVAS--------TT---TSRQTI---
---RKSPSPVLISLPRCRLTFPPAFKTTPVAFNPFLIPGMSPGLIYPSMFLSPGIGMALP
GLQPTRHSDSSSLESQKRKRKKARGDPPNP------DPETASGSEREPGHGQNCTEHT-P
PLPTDKERGVQAEESNLKETMTPTN

----------------------------------NMLFYFSLLQLSNLKVLNHSPMSDAS
VSFDYKSPSPFDCSTDQEEKI---EDVASQCLPQKDQYAVEE-----------EADTLFS
RKMTSHNGMENSGGGGTGVKKKRKKKDPGEQEGAAKRSRDREPKPKRKREPKEPKEPRKT
KEPKKAKE---PKELKQKDGAKKARKPREASGTKEAKEKRSTTDSLARTKSKKA-SKEQG
PTPVEKKKKGKRKNETTVESLELDQGLPNSSLRSPEDCAESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKMVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 519)

SLQVLPEIKHMERPASDSWQKLDKSREYKNSN

PF04851 // ENSGT00760000119067_8_Domain_2 (519, 688)

QLREYQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLAKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVADGTSDIPERGNTDKEDHVENKLDSAQKQTENSRDG--
-------GDGIFGEKKDDSRAAQDGSDSDKSPWPVSSALTARLRRLVTVYQRCNRKE-PC
RPEILGPANQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPLWKDVGSPDPTIYVEPITEER
AARTLYRIELLRKIREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPESLCCLYQTNSKLYESLAYTQMNRTSE
SLENEPENLLKIENR-DDHLSHPGGSLPDMVCENFISKVQDVISINHDDSLLPESLESMI
YGKKVLNQEPGPFQDSPSS-TN--AESRKETIPISASKNGNCQPSGHEAEIASIPS-FMS
SLEA-GIAQMNNKDGNHLMMSLS-KEGELCCSETGQKPDNF-------KLLE-PQCIAS-
--PSLDQENESGFV--NMYSLGIC--DSRRNLSSNQQLIDLLENRSLESKLILSPNHSDD
DEE-EEENE----------EESLDMAVGMRERPKVLHLVEPTSNIQ-----R--E---K-
SQGLHIDESK------------KGSLEMVNQNLGPQRAFP-QAACQCHCRHME-------
----------RWKHNM-END--DFQVEKPKC----YNPDLYKSKTNNIT-M--EGEPTAI
PSDPFKVKRELLK-ESWRESAEEK--KDFPMY----PLERNELKS-ENMDFENKDG-YDR
NENCHGQDYPGKYSEEESKSSTSGIIGDIGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSGQ-QYEPSGTL-PTPLLSGSATSRNSLLEPEASEHSFSNG
AALVAQVQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSASHGHPPIVLNGWH
GESAIDLSCTSEGSP-GTTSPFPVSSSTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDFIFLKEPSLQAGILEVH------EDPGQA
TLSTTTHSEGPVPATSAPETRTAASGQAEKAIPSKSLLDWLRQQS-DYSLEVPGFGTNFS
DKPKQRRPRCKEPGKLDAN

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2678)

SLSGEERVPTITKEPGP------------------------
-----------RGFLPENKFNHTLTEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLLMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPASFATMPTGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLSTPMATTCTSSAPASLSSTTKSGTSATEKTVEDKPSSRDVKMD
SLTEDKPGPSPFS----DQSEPTITTSNPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
SMQQARHSEVVGLENQKRKKKKTKGDNPNP------NPEPAPGSGREPSSDQNCTEPS-A
PLPPDRDHVAQAGDGGLKDSNNDTN

---------------------------------LGQKLQKKKKKLSSLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASH-LPQKDLYTTEE-----------DAATLFP
RKMTSHNGTEDSGGGGTGVKKKRKKKEPGEQEA-AKGGKDREPKPKRRREPKEPKEPRKA
KEQRKAKE---PKEPKQKDGAKKTRKPREASVPREAKDKRSCADSTARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNASLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 536)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFNW

PF00270 // ENSGT00760000119067_8_Domain_2 (536, 667)

YNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKSHSPDALDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLSDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EVICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTHARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLD--KVGMPDEKSLSAEQGVTDGTSDVPERGNTDKEDNAEDKLDGLQKQMESSSEG--
-------GDGIFGEKKDESRAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
AFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRSVCRLPAWKDSGPPDATIYIEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGSLCCLYQTNSKLYESLTYTQMNRTSE
SLENEPENRGKIESR-DDHLGL-----SDVTCENLISNVQDVISISHDESLLPETLDSVT
YGKKVLGQDSDSLQESPS--IS--AESRRDAAAVSGSPEETCHPGDQEAEVPSGPS-FLG
SLEA-RVAQVNIKNGKHLLLSTS-EEGDLCCNVAGPRPESI-------MQLG-AKCLAS-
--PSLDPGGESGFV--DMCSLSVC--DSKRNLSADQQLIDLLENKTLESKLILSQNHSDE
EEE-EEENE----------EENLSVAAGMRERPEVLHLTEPATNIP--------Q---EE
SRGFHFSEAK------------KESLEVVTQTPGPQRAFP-PAACQCHCKHMG-------
----------RWTRSL-KN---EFEVEKPEG----YNPDLYKSNTNSIT-L--EGEPTAI
PSEPFKVKQELLK-DPWKESTEGR--KGFPTY----LLEGSELKS-EDLDFENKDD-YDR
DRNCHSQDYPGKYSEEESKSSASGIAGDTGDELQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPLGTL-PTPVLTSSAGSRSILSEPEAAEHSFSNG
AALAAQIQKESFLTPVFTKDEQKHRRPFEFEVER-DTKAPCLKQLSAAQGHPPIVLNGWH
GETAIDLSCSSDGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAS-RRRRGRRRHAEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-TQPEGPGPATLAPEPAATAGNQGEKAVPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDISSLSGEEGVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--GGP-RRRGRRPRSELLKGPAIV-TDSP
SGMGPLFMNGLIAGMDLVGLQSMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNAPMATTCTSTAPASLSSTTKSGTAAPEKTAEDKPSSHDGKTD
TVAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPSP------NPDPAPSCEREPGSDQNCTEPS-A
LAPPERELVAQAGEGTLKDSNSDTN

---------------------------------MIMKIQKKEKQLSSLKVLNHSPMSDAS
VNFDYKSPSPFDHGTDQEEKI---EDVASHCLPQKDLYAAEE-----------EAETLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPGEQEGAAKGSKDREPKPKRKREPREPKEARKA
KEPKRAKE---PKEPKQKDGVKKARKPREASGTKEAKEKRSGVDSAARTKSKKA-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRVLEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTEGTSDIPERGNTDKEDNTEDKLDGLQKQMESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVPSALTARLRRLVTVYQRCNRKE-LC
RPEVLGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRAVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPTWKDGGPPDPSIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLVGTAKHGL
NRTDYYIMTDPQLSFLDAYRNYAQHKRTDAQAPESLCCLYQTNSRLYESLTYTQMSRTSE
PLENEPENLVKIESR-DDHLAPPGGSLSDMTCDNFISKVQDVISITHDESLLPESLESMM
YGKRALIREPGSLQESPS--TN--TEPRKDALALSASKDGNCRPDGHEAEIPSGPS-FMS
SLEA-GVAQMNIKNGKHLLLSLS-REGDVC-SEAGQRPEGI-------GQLE-AKHSAS-
--PSLDQGNESGFV--DMCHLSVC--DSRRSLSSDQQLIDLLENKSLESKLVLSQNHSEE
EEEE-EENE----------EENVGVTTGLRERPEVLHLAEPT------ANIL--R---EK
SRGLPVDEVK------------RGSLEAMSQHPRPQGAFP-PAACQCHCKHTE-------
----------RWARGL-ENE--EFEVDKSKG----YTPDLYRSKTNSIT-V--EGEPTVP
PSEPFQGKHELSK-EPWKENAEGK--KGFPAY----P-EASELKS-EDMDFESKDD-YDR
DGNSHAQDYPGKYSEEESKSSASGIAGDLGDDLQEARAPTIAQLLQEKTLFSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPPGTL-PTPVLTSSAGSRSSISEPETSEHSFSSG
AALVAQIQKESFLAPVFTKDDQKHRRPYEFEVER-DAKARGLDQFSATHGHPPIVLNGWH
GESAIDLSCTSEGSP-GAASPFPLSASTPKIGAVG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
PSSASH-PEGPVSAASAPEPAPAAGSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGANFS
GKPKQRRPRCKEPGKLDVNSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRSELLKTPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNLPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMATACTNTAPAPLSSTTKSGTAPTEKTVEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEAVGLESQKRKKKKTKGDSLNP------NPEPAPGSEKEPGGDQNCPEPR-A
PVPPERGHVAQAREGGLKDSNSDTN

---------------------------------MIMKIQKKEKQLSNFKVLNHSPMSDVS
VNFDYKSPSPFDCSTDQEEKI---EDVASQCLPQKDLYATEE-----------EADTLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKNPGEQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKVKE---PKEPKQKDGAKKVRKPREASGTKEAKEKRSGADSTARTKSRKS-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

KQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQVLPEIKHAERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLAKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGAPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNMDKEDNAEDKSHGHQKQTESSSDG--
-------GDGIFGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-PC
RPEILGPGNQGYWVQEEMFRRTAEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPTWKDGGAPDPTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTNTQAPESLCCLYQTNSKLYESLTYTQMSRTSE
SLEIEPENLVKIESR-ENHLGQPGGSLPDITCENFISKVQDVISINHDESLLSESLESMM
YGKTVFSQEPGSFQESLSS-SN--ADSRRDTVAISASKDADCQPGGHEADIASGPS-FMG
ILEA-GVAQMNNKNGKHLLMSIS-EEGELCCSEAGQRPESI-------RHLE-TKCMAS-
--PSLDQGNESGFV--DMCNLSVY--DSKTSFSANQQLIDLLENKSLESKLILSQNHSEE
EEE-EEDNE----------EENLDMAAD-IKRPEVLHLTEPSTAIP-----R--E---E-
NRGFRVGEAK------------KGSLEAMSPSPGPQRAFP-PAACQCHCQHME-------
----------RWKTGI-END--DFEVEKPRG----YNPDLYKSKANNIT-A--ESEPTAI
PSEPFKVKHELLK-EPWKESAEGK--KGFPTY----PLEGSELKS-EDTDFENKDD-YDR
NGHCHSQEYPGKYSEEESKSSTLGMAGDIGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIMNRLDNICHVVLKGKWPSSH-QYEPSGTL-STPVLASGAGSRNSLSEPETSEHSFSNG
TALVAHIQKESFLAPVFTKDEQQHRHPYEFEVER-DAKARSLEQFSATRGHPPIVLNGWH
GESAIDLSCTSEGAP-GATSPFPVSASTPKIGTIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPVPATSASETVAAASSQAEKAIPSKSLLDWLRQQS-DYSLEIPGFGANFS
DKPKQRRPRCKEPGKLDVNSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPAVPKEPGP------------------------
-----------RGFLPENKFNHTLTEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLNTPMATTCTSTAPASLSSTTKSGTSVTEKTAEDKPSSRDVKTD
TLAEDKPGPSPFS----DQAEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
TMQQARHSEIIGLESQKRKKKKTKGDNPHP------NPEPAPGSERESISNQNCTEAS-A
PLPPDREHMAQAGDGGPKDSNTTTN

---------------------------------MIMKIQKKEKQXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----X-X--XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-X--X---XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX--
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRNKQAQMKHIFTEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEVTHYLVKWCSLPYEESTWELEEDVDPAKVKEFESLQVLPEIKHAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLAKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDASDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN---LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQTEGKGST--FAKASFVASGNRTDISLDDPNFWQKWAKIAELDTEAKSEKESLVIDRPRVRKQTKHYNSFEEDELMEFSELDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDIVTHGRFKWHLNEKDMEMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTKNQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AADKAFEGAPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PALCFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKLDSLQKQTESSSDG---------GAGILGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRVVTVYQRCNRKE-PCRPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKXXXXXXXXXXXXXXXXXXXXXXQEKKTFDWTQFRIISRLDKKSDESLEHYFHSFVAMCRNVCRLPAWKDGGPRDPTIYFEPITEE-AARTLYRIDFLRKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRTSESLENEPENLVKLEST-ENHLGQPGGSLADITCENFISKVQDVISINHDESLLPEALESVMYGKTVFSQEPNSFQESLSSSSA---DSRRGSVAISTSKDGDYQPGGHETEIASSPS-VMGILEA-GVAQMNSKNGKHLLMSLS-EEGELCYGEAGQRPESIRH-------LE-ATCMAS---PSLDQGNESGFV--DMCPLSVC--DPKTSLSVNQQLIDLLENKSFESKLILSQNHSEEEEEEEENEV-----------ENLDLAVD-LKRPEVLHLTEPAAAIPG-----------EKNRGFHIGETR------------KGSSEVVSPSPRPQETFP-AAACQCHCKHME-----------------RWKAGT-EKE--DFEVEKPQG----YDPDLYRSKANNV---AAEREPAVVLPEPFKVKRELLK-EPWEESAEVK--KGFPMY----PLEGGELKS-EDMDFENKDD-YDRNRHCHSQDYPGKYSEEDSKSSPRGLVGDTGDELQGARAPTIAQLLQEKTLYSFSEWPKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXESFLAPVFTRDEQQRRHPYEFEVEK-SAEAQSLEQFSATHGHPSVVLNGWHGESAIDLSCTSEGSP-GATSPFPVSASTPKIGTIS--SLQGALGMDLSGILQAGVIHPVTGQIVNGSLRRDDIAS-RRRRGRRKHVEEGMDLIFLKDQTLQAGILEVH------EDPGQATPSS-THPERPVPVTSAPETAAAASSQAEKAVPSKSLLDWLRQQSDD-YFEGPGFGTXXXXXXXXXXXXXXXXXXXXXXXX-----------------------------------XXXXXXXXXXXXXXXXGFLPENKFNHTLPEPVLRD--AGP-RRRGRRPRSELLKAPALV-ADSPSGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEDVKSTLSMLPMMLPGMATVPQMFGVGGLLNTPMTTTCTSTAPASLSSTTKSGTSAPAKTAEHKPSSHEGKTEPLGEDKPGRSPFS----DQSEPAVTSSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALPTMQQRH-S--ESLESQKRKKKKPDNLP-Q--------P----EVPVRESSSQNCEAST----LPDREHVAQAGDGPK-DSRN

PF00176 // ENSGT00760000119067_8_Domain_2 (410, 811)

FRNKQAQMKHI
FTEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFESLQVLPEIKHAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLAKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQTEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKSEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDIVTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGAPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKLDSLQKQTESSSDG--
-------GAGILGEKKDDSQAAQDGSDPDKSPWPVSSALTARLRRVVTVYQRCNRKE-PC
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKXXXXXXXXXXXXXXXXXXXXXXQEKK
TFDWTQFRIISRLDKKSDESLEHYFHSFVAMCRNVCRLPAWKDGGPRDPTIYFEPITEE-
AARTLYRIDFLRKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRTSE
SLENEPENLVKLEST-ENHLGQPGGSLADITCENFISKVQDVISINHDESLLPEALESVM
YGKTVFSQEPNSFQESLSSSSA---DSRRGSVAISTSKDGDYQPGGHETEIASSPS-VMG
ILEA-GVAQMNSKNGKHLLMSLS-EEGELCYGEAGQRPESIRH-------LE-ATCMAS-
--PSLDQGNESGFV--DMCPLSVC--DPKTSLSVNQQLIDLLENKSFESKLILSQNHSEE
EEEEEENEV-----------ENLDLAVD-LKRPEVLHLTEPAAAIPG-----------EK
NRGFHIGETR------------KGSSEVVSPSPRPQETFP-AAACQCHCKHME-------
----------RWKAGT-EKE--DFEVEKPQG----YDPDLYRSKANNV---AAEREPAVV
LPEPFKVKRELLK-EPWEESAEVK--KGFPMY----PLEGGELKS-EDMDFENKDD-YDR
NRHCHSQDYPGKYSEEDSKSSPRGLVGDTGDELQGARAPTIAQLLQEKTLYSFSEWPKXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXESFLAPVFTRDEQQRRHPYEFEVEK-SAEAQSLEQFSATHGHPSVVLNGWH
GESAIDLSCTSEGSP-GATSPFPVSASTPKIGTIS--SLQGALGMDLSGILQAGVIHPVT
GQIVNGSLRRDDIAS-RRRRGRRKHVEEGMDLIFLKDQTLQAGILEVH------EDPGQA
TPSS-THPERPVPVTSAPETAAAASSQAEKAVPSKSLLDWLRQQSDD-YFEGPGFGTXXX
XXXXXXXXXXXXXXXXXXXXX-----------------------------------XXXX
XXXXXXXXXXXXGFLPENKFNHTLPEPVLRD--AGP-RRRGRRPRSELLKAPALV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLNTPMTTTCTSTAPASLSSTTKSGTSAPAKTAEHKPSSHEGKTE
PLGEDKPGRSPFS----DQSEPAVTSSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
TMQQRH-S--ESLESQKRKKKKPDNLP-Q--------P----EVPVRESSSQNCEAST--
--LPDREHVAQAGDGPK-DSRNHTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVARHCLPQQDIYTTEE-----------EADTLFP
RKVTSCNGTEDSGGGGTGVKKKRKKKDPGEQGGTAKGNKDREPKPKRKREPKEPKEPRKT
KEPKKARE---PKEPKQKDGAKKARKPREASGTKEAKEKRSSADSAARTKSKKA-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 533)

SLQVLPEIKHVERPASDSWQKLDKSREYKNSNQLREYQLEGMNWLL

PF00176 // ENSGT00760000119067_8_Domain_2 (533, 811)

FNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPTQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKMK
NQLLLPELKNADWLTTCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGAPARELDVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGGTDGTSDIPERGNMDKEDTTEDKLDGLQKQTENSSDG--
-------GEGVFGEKKDDSRAAQDSSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKETQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYNFVAMCRNVCRLPAWKDGGPPDATVYIEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGSLCCLYQTNSKLYESLTYAQMSRTSE
SLESEPENLVKIESR-DDPLGLPGGSFPDVTCDNFISKVQDVISINHDESLLPESLENMM
YGNKVLSPEPGSFQEGPV--IN--TECRKDTVVISASKNAGCRPGDREAEIAA-VS-LMD
TIEA-GVAQMNIESGEHLLTPIS-KERERCCGEAGRRPESL-------GQLE-AKCLPS-
--TALDAGNESGFV--DMCSLSVC--NSKRNLSSDQKLIDLLQSKSLETKLILSQNQSDE
EEE-EDENE----------EETLAMAAGTREKPEALHLTSPTANNP-----R--E---K-
SQGFHLDEAK------------KGSLEVVSQTPGPPRAFP-PASCQCHCKHVE-------
----------RWAHGL-GND--EFEVEKPKA----YHPDLYKSKANNTT-M--EGEPTTI
PSEPFKVKPELLK-EPWKECAERK--KGFSTY----APEGSEPKS-EDMDFENKDD-YDR
DGTCQSQDYPGKYSEEESKSSASGIAGDLGDDPQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDSICHVVLKGKWPSSQ-QYEPSGTL-STPVLVNSAGSRNSLPEPEAAEHSFSNG
ATLAAQVQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSATHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSANTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAM-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPAQA
TLST-THPEGPGPATSAPEPAVAANGQAEKTIPSKSLLDWLRQQA-DYSLDVPGFGANFS
DRPKQRRPRCKEPGKLDISSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNVRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNPPMATTCTSTAPASLSSTTKSGTAATEKTAEDTPGGHDVKAD
TLAEDKPGPSPFS----DQSESAITTSSPVAFNPFLIPGMSPGLIYPSMFLSPGMGMALP
AMQQARHSEVVGLESQKRKKKKTKGDNPNPNPNPNPNPEPAPGCEREPGADQNCTESS-T
PVPPERQHVTQPGEGGLKDSNSDTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEDKI---EDVASHCLSQKDLYTTEE-----------DAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGEQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---PKEPKQKDGAKKARKPREASGTKEAKEKRSCADSAARTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKYHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKLDGLHKQTESASEG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDGGLPDATIYIEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGSLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKIESR-DDHLGL-----PDVTCENLISKVQDVISVNRDESLLPESLESVM
YGKKMLSQEPGSFQESPS--TS--TESGRDAAAISASQDGNCQPGGQEAEVGLGPS-FLS
SLEA-RVAQVNIRNGKHLLMSTS-EEGEFCCNVAGPRPEGI-------GQLE-TKCLAS-
--PSLDPGGESGFV--DMCNLSVC--DSKRNVSADQQLIDLLENKSIESKLILSQNHSDE
EEE-EEENE----------DENLAVAADMRERPEVLHLTEPTTNIP--------R---EK
SRGFHVNSAK------------KGIPEVVNQTPGPQRAFP-PTACQCHCEHME-------
----------RWTHGL-END--DFEMEKPEA----YNPDLYKSKANNIT-V--EGEPTAV
PSEPFKVKHELLK-EPWKESAEGR--KGFPTY----LVERSELKS-EDTDFENKDD-YDR
YGNCHIPDYPGKYSEEESKSSTSGIVGDTGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPLGTL-PTPVLTSSAASRNSLSEPEAAEHTFSNG
TALAAQMQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSAAHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSTSTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVDGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPASSASEPAAAAGSQAEKAIPSKSLLDWLRQQA-DYSLEVPSFGANFS
DKPKQRRPRCKEPGKLDISSLSGEEGIPAVPKEPEL------------------------
-----------RGFLPENKFSHTLAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQSMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNAPMATTCTSTAPASLSSTTKSGTAATEKTAEDKPSSRDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQSRHSEIVGLESQKRKKKKTKGDNLNP------NPEPAPSCEKEPGSDQNCTESS-A
PVAPERELVAQAGEGKLKDSNNTN-

-------------------------------MFFKVQKLFILISLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGVKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPGSFRESPS--TN--TECRKDVITISISKDGNCQPGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEEDLCFSEAGQRPESI-------SQLE-AKCLAS-
--SSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTIDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTSTIA-M--EGEPTAV
ASEPFKVKHELLK-EPWKEGAEGQ--KVFPTY----PLEGSELKA-EDMDFENKDE-YDR
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSVGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTARDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDENCAEPS-A
LLPAEREHVAQAGEGAPKDSNDDTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGVKKARKPREASGTKEAKEKRSCTDPAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPGSFRESPS--TN--TECRKDVITISISKDGNCQPGGHEAEIASRPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEEELCFSEAGQRPESI-------SQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-E--EN----------EENLAMAVGMGERPEVLHLTEPTIDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFLPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTNTIA-M--EGEPTAV
PSEPFKVKHELLK-EPWKESAEGQ--KVFPTY----PLEGSELKS-EDMDFENKDE-YDR
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSAGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFAKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGTNFS
DKPKQRRPRCKEPGKLDVSSLSGEERVTAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMTAVPQMFGVGGLLSPPMATTCTSTAPVSLSSTTKSGTAVTEKTAGDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDENCAEPS-A
LLPAEREHVAQAGEGALKDSNNDTN

---------------------------------MIMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDRSTDQEEKI---EDVASHCLPQKDLYAAEE-----------EAEALFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPGEQEGPAKGSKDREPKPKRKREPREPKEPRKA
KEPKRAKE---PKEPKQKDGAKKARKPREASGTKEAKEKRSSADSIGRTKSKKA-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRVLEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 523)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 809)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHP

ENSGT00760000119067_8_Linker_2_4 (809, 881)

YLING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNMDKEDNTEDKSDSPQKQPESSSDG--
-------GDGIFGEKKEDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPVNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRAVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPTWKDGGPPDPSIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLVGTAKHGL
NRTDYYIMTDPQLSFLDAYRNYAQHKRTDTQAPESLCCLYQTNSKLYESLTYTQMSRTSE
PLESEPENLVKIEGR-DGHSTPPGVSLSDMTCENFISKVQDVMSVTHDESLLPECLEGMM
YGKKALSREPGSFQESPT--TR--TEPRKDALALSAGEDGNCQPGGREAELPAGPS-FLS
SLEA-GVAQMNIKNGKHLLLSLS-REGDLC-SETGQRPESI-------GQLE-AKCLAS-
--PSLDQGNESGFV--DMCNLSVC--DSRRSLSSDQQLIDLLENKSLESKLVLSQNHSDE
EEEEEEEKE----------EDNAGAAAGLRGRPEVVRLADPTAHIHPTAHIL--R---EK
SRGFHVEEAK------------RGTLEAVSQNPGPRGALP-QAACQCPCKHTG-------
----------RWTRGL-ENE--EFEVEKPKG----YNADAYKSKTSSIP-V--EAEPPAP
PAEPAQGKHELLS-EPWKDSAEGK--KAFAVY----P-EASELKS-EDADFESKDD-YDR
EGNGHTQDYPGKYSEEESKSSTSGIAGDLGDDLQEARAPTIAQLLQEKTLFSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-PYEPSGTL-PTPALSSSAGSRSSASEPEASEHGFSSS
AALVAQIQKESFLAPVFTKDEQKLRRPYEFEVER-DVKARSLEHFSATHGHPPVVLNGWH
GESAIDLSCTSEGSP-GATSPFPVSASTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
QPSTSH-PEGPVPAASAPEPAPAAGIQAEKAIPSKSLLDWLRQQA-DYSLEVPSFGANFS
DKPKQRRPRCKEPGKLDIN

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2678)

SLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADAP
AGMGPLFMNGLIAGMDLVGLQNMRNVPGIPLTGLVGFPAGFAAMPTGEEVKSSLSMLPLM
LPGMAAVPPMLGVGGLLNAPMAAACPSAAPAPPPSTTKSGTAAPEKTVEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEVLGLESQKRKKKKTKGDSLNP------NPEPAAGSEKEPGSDQNCPESR-A
PGPADREHAAQAREGGLKDSNSDTN

-------------------------------MFFKVQKLFILISLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGVKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPGSFQESPS--TN--TECRKDVITISISKDGNCQPGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEEDLCFSEAGQRPESI-------SQLE-AKCLAS-
--SSLNPGNESGFV--DMCSFSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTIDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTSTIA-M--EGEPTAV
ASEPFKVKHELLK-EPWKEGAEGQ--KVFPTY----PLEGSELKA-EDMDFENKDE-YDR
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSVGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAGDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDENCAEPS-A
LLPAEREHVAQAGEGAPKDSNDDTN

-------------------------------MKMKI--QKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGSPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQAESSSDG--
-------GDGVFSEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSGTQAPGNLCCLYQTNSKLYESLTYSQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPSSFQESPS--TN--TESRKDVITISISKDGNCQSGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEGELCCSEAGQRPESI-------GQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTTNIS--------R---EK
NQGFQ-DETK------------KGSLEVANHTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKV----YIPDLFKSKTNTIA-M--EGEPTAI
PSQPFKVKHELLK-EPWKESAEGQ--NVFPTY----PLEGSELKS-EDMDFENKDD-YDR
DGNCHSQDYPGKYSEEESKSSTSGITGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSAGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSSSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-IHPEGPGPATSAPEPATAASSQAEKSIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAIPKEPGL------------------------
-----------RGFLPENKFNHTLAEPILRD--TGP-RRRGRRPRSELLKAPSTV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSGDENCAEPS-A
PLPAEREHGAQAGEGALKDSNNDTN

---------------------------------MIMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFEHSTDQEEKI---EDVASHCLSQKDLYAAEE-----------EAETLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPGEQDGAAKGSKDREPKPKRKREPREPKEPRKA
KEPKRAKE---PKEPKQKDGAKKARKPREASGTKEAKEKRSGADTAARTKSKKA-SKEQG
PTPVERKKKGKRKSETTVESLELDQGLPNSSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRVLEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 523)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNMDKEDNTEDKLDGLQKQMESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRAVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPTWKDGGPPDPSIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLVGTAKHGL
NRTDYYVMTDPQLSFLDAYRNYAQHKRTDAQAPESLCCLYQTNSKLYESLTYSQMNRTSE
PLENEPENLVKIEGR-DDHPPPPGGNLSDMSCENFLSKVQDVISITHDESLLPESLESMM
YGKKALSQEPGSFQESPS--T---IEPRKDALASSASEEGKCQPGGHEAEIPTGPS-FMD
SLEA-GVAQMNIKNGKHLLLSLS-REGELC-SETGQRPESI-------GQLE-AKCLAS-
--PSLDQGNESGFV--DMYNLSVC--DSRRSLSSDQQLIDLLEDKSLESKLALSQTHSDE
EE-E-EENE----------EENVGVATGLRERPEVLHLAEPT------ADTL--R---EK
SRSFHVEEAK------------RGGLEAMNQNPGPQGAFP-QAACQCHCKHAD-------
----------QWTRGL-ENE--GFEVEKPKG----YHPDMYKSKTNSVT-V--EGEPTAT
PAEPPQGKHELLK-EPWKDSAEGK--KGFHVY----S-EASELKS-EDMDFESKDD-FDR
DGNGHAQDYPGKYSEEESKSSTSGIAGDLGDDLQEARAPTIAQLLQEKTLFSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTGSAGSRSSLSEPEASEHSFSSS
AALVAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSATHGHPPIVLNGWH
GESAIDLSCTSEGSP-GATSPFPVSASTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
PPSASH-PEGPVPAAPAPEPTPAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVN

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2675)

SLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLAEPVLRD--GGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFAAMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMAAACTSTAPAPLPSTTKSGTPATEKTVEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEVIGLESQKRKKKKTKGDSLNP------NPEPAPGSEKEPGSDQNCPESR-A
PVPPDREHAAQAREGGLKDSNSDTN

---------------------------------MIMKIQKKEKQLSHLKVLNHSPMSDAS
VNFDYKSPSPFDRSTDQEEKI---DDVASHCLPQKDLYAAEE-----------EAETLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPGEQEGAAKGNKDREPKPKRKREPREPKPPR--
-------EPRRAKEPKQKDGAKKARKPREASGTKEAKEKRGGAESASRTKSKKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

KQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

IEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVREFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQVLPEIKHVERPASDAWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSSDAPDFQLQAM
IHAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTADIPEXXXXXXXXXXXXXXXXXXXXXESSSDG--
-------GDGIFSEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-VC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDGGPPDPTIYVEPITEER
AARTLYRIELLRKVREQVLTCPH-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMTDPQLSFLDAYRNYAQHKRPDTQAPESLCCLYQTSSKLYESLTYTQMSRTSE
SLENEPDNLGKIEGR-NDHLGPPRGSLSDMTCENFISKVQDVISITRDESLLPESLESMM
YGKKVLSREPGSLQESPS--TS--IGSRKDAVAISASRDRDCQPGGHEAEIASSPS-FMD
SLEA-GVAQMNIKNEKHLLMSLS-REGDLCCSEAGQRPESI-------GQLE-AKCLAS-
--PSLDQGNESGFV--DMCNLSVC--DSKRNLSSEQQLIDLLENKSIESNLILSQNHSDE
EEEEEENE-----------EESLDMAACLRG-PEVLPLTEPTAHIP--------R---EK
SRGFHIEAR-------------KGSLEAVSQNPRLQGPFP-QAACQCHCKHVE-------
----------RWTRGL-ESD--EFEVEKPKG----YNPDLYKSKTNNI---TVEGELTAI
PSEPFPVKHELLK-EPWRDSAEGK--KGFPVY----PPEGSELKS-EDVDFESKDD-YDR
DGNCHSQDYPGKYSEEESKSSTSGITGDIGEDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINPLDNICHVVFKGKWPSSQ-QYEPST--LPTPLLTSSXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXESFLAPVFTKDEQKHRRPYEFEVER-DAKVQSLEQFSATHGHPPIVLNGWH
GESAIDLSCTSEGSP-GATSPFPVSASTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKDQTLQAGILEVH------EDPGQA
PLST-SHPEGPVPAPAAPEPAPAAGSQAEKAIPSKSLLDWLRQQADDYSLDVPGFGANFS
DKPKQRRPRCKEPGKLDVSSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPAVPKEPGL------------------------
-----------RGFLPENKFGPTLTEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPASFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNAPMATTCTSTAPAPLSSTTKSGTSVTEKTAEDKPSSHDVKTD
TLAE-QPAPSPYSXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXLP
AMQAR-H--------------LIAGETRERETDLNPNPEPAPGSEREPGSEQNCPER--A
PVPSDREHAAQARGRGLKDSNSDTN

---------------------------------INLFIDRLLKQFSNLKVLSRSPMSDAS
VTCEYKSQSSFVSSTDQEEKI---TDLASHCILQKDLYPAE------------DADHLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPSEQEAVEKEVKDREPKPKRKREPKEPKEPKKA
KEPKKQKE------PKQKETVKKARKPREPRLSKDAKDKRGSTDSTPRMKTKKA-SKEQG
PTPVEKRKKGKRKNDTSVENLELDQGLLSPSNRNPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKMVQKEV
H----PGELPFDMELFYVKYRNFSYLHCKWATM-EELEKDPRISQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDSDTGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 519)

SLQILPEIKHVERPASDSWQKLEKSREYKNNN

PF04851 // ENSGT00760000119067_8_Domain_2 (519, 688)

QLREYQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLMGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMLYRDAQGNPLSGIFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLAKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDSLDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLTKIEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTDAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNEKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWDLITPTKDGQNQALQNHSGLSAPVPRGRKGKKTK
NQMLLPELKNADWLATCNPEVVLHDDSYKKHLKQHCNKVLLRVRMLYY-LKSEVLGE-AA
DKAFEGISARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVVKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGSQDISERSNLDKDDHTEDKLDGLQKQLLIPSAV--
-------ASQKFCVSTEDRQGAQDGSDPDRSPWPVSSALTARLRRLVTVYQRCNRKE-PT
RAEILGSGNQGYWVQEDMFRRATEMDPINKDIQKRWTRREQADFYRTVSSFGVVYDQEKK
SFDWTQFRVISRLDKKTDESLEKYFYSFMAMCRNVCRLPMWKDDGPPDPTLYVEPITEER
AARTLYRIELLRKVREQVLKYPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
SRTDYYIMNDPQLSFLDAYRNYAQHRRTETQGPDNACCLYQTNSRLYESLTYTQMGRTCE
SLDTEHENQIKMESMGD-NLSHTESNLPDVTCENFISKVQDIISINHDESLLPDSLECMM
FGEKVFNSEPSSFIQENL--SS--TDCKKDVSLALASKNKENQPGSLEVEIGTNRC-SLS
NLEA-KIEQMSNKNEKHLSLLTI-KDLDSNKYIPAPRHEIV-------RHPE-AKYGIP-
--QTIEQGNVSRLM--EMCSLSVC--NSERKLSSGQQLIDLLGNKSLEGKLMLTRNHSDE
EEEEEEEEE----------EENSEVGTQIRERPESIGQTDLDINIP--------N---EM
-RGFTIDKTK------------ERVPETQNCDPAELRRM-DQTVCKCHCKPID-------
----------RWKNQG-DTM--DFEMEKTRF----PDPGLYKGKAVNTIAVEYKGGNKTL
LSEPLKVDHEFLKEDSWEDKAERR--RGYTTC----PLERSDLKQ-EDVDFENKEDDDDK
DGNLQGQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRIDNICHAVLKGKWPSSQ-QYEMPSTL-PAPVLISSPGSRNSLAEQETPGPNFSNG
AALVTQIPKENFLAPVFAKDERKHRRPYEFDMER-DLKARSLEQLSASHGHPPIVLNGWR
GESAIDLSCTPDGSP-ATTSPFPLSTSTPKIGTVS--TLQGSLGMDLSGILQAGLIHPVT
GQIVNGTLRRDDAAM-RRRRGRRKNVEGGMDLIFLKDRTLQTGILEVQ------EEQEQP
SPSS-TLPDGPISATSSPHTVTTTSVPAEKTIPNKSLLDWLRQQS-DYALEVPTFGANFS
DKPKQRRQRCKEPGKLEMG

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2678)

SLSGEERVPAVHKETGR------------------------
-----------QGFLPENKFSQILTEPVLRD--AGP-RRRGRRPRSDLIKAPGIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMQGIPLTGLVGFPAGFAAVPAGEDVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMTTTCTSTVPTSLTSTTKSGTSNTEKAADDKQNSHDVKKD
TLAEDKPIPSSFS----DQSEPAITTSSPVAFNPFLLPGMSPGLIYPSMFLSPGIGMTLP
GMQQTRHSENTSLESQKRKRKKAKGDILNP------DPETIPISEKESGNGQNCSEHT-P
LLPSDKEHDVQAEQSNLKGTHSDTN

-----------------------------------MKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDHSTDQEEKI---EDVASHCLPQKDLYAAEE-----------EAETLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPGEQEGAAKGSKDREPKPKRKREPREPKEPRKA
KEPKRPKE---PKEPKQKDGAKKARKPREASGTKEAKEKRSGTDSAARTKSRKS-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 536)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFNW

PF00270 // ENSGT00760000119067_8_Domain_2 (536, 667)

YNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLSKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2600)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELEVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNMDKEDSTEDKLDGLQKQMESSSDG--
-------GDGTFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCHLPAWKDSGAPDPTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYIMTDPQLSFLDAYRNYAQHKRTDTQAPESLCCLYQTNSKLYESLTYTQMNRTSE
SLESEPENLVKIEGR-GDHLNPPGGSLSDMTCENFISKVQDVISITHDDSLLPESLESVM
YGKKALSRELGSFQESPS--TN--TESRRDADAISASKDGNLQLGSHEAELASGPS-LMD
SLEA-GVAHMNIKNEKHLLMSLS-KEGELCCSEAGQRPESS-------GQLE-AHCLAS-
--RSLDQGNESGFV--DMCNLSVC--DSKINLSSDQQLIDLLENKSLENKLILSQNHSDE
EEEE-EENE----------EENLDMASGMRERPEVLHLAEPT------ADIP--R---EK
SLGFHVDEAK------------KVSMEAVSQNPGPPGAFP-QAACQCHCKHME-------
----------RWTRGL-EYD--EFEVEKPKG----YNPDLYKSKTNNIT-M--EGEPTAI
PSEPFQMKHELLK-EPWKENAEGK--KDFLTY----TLEGSELKS-EDMDFESKDD-YDR
DGNCHNQDYPGKYSEEESKSSTSGITGDLVEDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTV-PAPVLTSSAGSRSSLSEPEASEHSFSSG
AALVAQIQKESFLAPVFIKDEQKHRRHYEFEVER-DAKARSLEQFSATHGHRPIVLNGWH
GESAMDLSCTSEGSP-GATSPFPVNTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIINGSLRRDDAAS-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGPA
PLSTSH-PEGPVPATSAPEPAPAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVN

PF07533 // ENSGT00760000119067_8_Domain_5 (2600, 2678)

SLSGEERVPAVSKEPGL------------------------
-----------RGFLPENKFNHTLPEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPASFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNAPMATTCTSTAPAPLSSTTKSGTSTTEKTAEDKPSSHDVKTD
ALAEDKPGPSPFS----DQSGPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNP------NPEPAPGSEREPGSDLNCPESR-A
RVPPDRDHVAQPREGGLKDSNSDSN

-------------------------------MKMKI--QKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGAKKARKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGSPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKVDGLQKQTESSSDG--
-------GDGVFSEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSGTQAPGNLCCLYQTNSKLYESLTYSQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPSSFQESPS--TN--TESRKDVITISISKDGNCQSGGPEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEGELCCSEAGQRPESI-------GQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMVVGMGERPEVLHLTEPTTNIS--------R---EK
NQGFQ-DETK------------KGSLEVANQTPGLQRAFPAPAACQCHCKHME-------
----------RWMHGL-END--EFEIEKPKA----YIPDLFKSKTNTIA-M--EGEPTAI
PSQPFKVKHELLK-EPWKESAEGQ--NVFPTY----PLEGSELKS-EDMDFENKDD-YDR
DGNCHSQDYPGKYSEEESKSSTSGITGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSAGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSASTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPATSAPEPATAASSQAEKSIPSKSLLDWLRQQA-DYSLEVPGFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAIPKEPGL------------------------
-----------RGFLPENKFNHTLAEPILRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAEDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPCGDENCAEPS-A
PLPAEREHGAQAGEGALKDSNNDTN

-----------------------------------MKIQKKEKQLSSLKVPNHSPMSDAS
VNFDYTSPSPFDHSTDQEEKI---EDVASHCPAPKELYNVEE-----------EAGPLFP
RKTVSHNGMEDSGGGGTGVKKKRKKKDPGEHEGAAKGSKDREPKPKRKREPRELKEPRKA
KEPRKAKE---PREPKQKDGTKKARKPREKARKARLEKHRASSSDARFKKGKKT-NKEQG
PTPVEKKKKGKRKSETAVESLELDQGLPNPSLRSPEESTESADSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 411)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRF

ENSGT00760000119067_8_Linker_0_1 (411, 435)

RNKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 519)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSN

PF04851 // ENSGT00760000119067_8_Domain_2 (519, 688)

QLREYQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYLING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKSEKESLVLDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKKELWALSL---VNLLPPLYQKNLKGNLNRVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKLLSAEQGVTDGASDVPERGNTDKEDNTEDKADGLQKQMESSNDG--
-------GDGLFAEKKDDTRA----------------ALTARLRRLVTVYQRCNRKE-LC
RPEVLGLGNQGYWVQEEMFRRSSEMELINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRVISRLDKKSDESLEHYFYSFMSMCRSVCRLPAWKDGGPLDPSIYVEPITEER
AARTLYRIELLRKVREQVLTCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDYYVMTDPQLSFLDAYRNYAQHKRPDPQAPESLCCLYQTNSKLYESLAYTHMSRTSE
SLENEPENLMKIEGR-DDHLGPPRGSLSDMTCESFISKTQDVLSLTHDESLLPGSLETMM
YGKKALSREPGPFQSSTG--AI--TESKQDTVAIPASRDRNCQPRGHEAKIASDPS-FME
TLEA-GVAQMNIKNEKHLLMSLS-KEGELGCSEAGPRPESI-------GQLD-SNCFAS-
--PSLDPGNESGFV--DMCNLSVC--DSRRNLSSDQQLIDLLESKSLESKLVLGPNHSDE
EDD-EDDNE----------EESLELAAGRQERLAASPLSEPTTRMT-----G--E---QS
LAGFLTEEAK------------RGSTEATSQPPGPQGPFL-PTACQCHCRHVE-------
----------RWTRGL-EKD--EFEVEKPQA----YPPDPFTSKANNVT-M--RGEPTAV
PPELFQVKQELLK-EPWKESTEGN--QGLPPY----P-EGSELKP-EDMDYESKEE-FDK
DGNCQSQDYPGKYSEEESKSSTSGITGDLGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICQVVLKGKWPSSQ-QYEPSGAL-PTPMLTSSAGPRSGLSEPEASEHSFSNG
AALVAQMQKESFLAPVFTKDEQKHRHPYEFEVER-DVKTRSLEQFSATHGHPPIVLNGWH
GESAIDLSCPSEGSS-GATSPFPVSASTPKIGAVG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAS-RRRRGRRKHVDGGVDLIFLKEQTLQAGILEVH------EDPGQA
PLSTPHP----LPATSTPEPTPAAGSPAEKAIPSKSLLD-----A-DCSLEVPGFGANFS
DKPKQRRPRCKEPGTLDVTSLSGEERA-AVPKEPGL------------------------
-----------RGFLPENKFNHTLPEPILRD--TGPPRRRGRRPRSELLTPPALV-ADAP
SGMGPLFMNGLIAGMDLVGLQNVRNVPGIPLTGLVGFPAGFAAMPPGEEVKSTLSMLPMV
LPGMAAVPQMFGVGGLLNAPMATTCASAVPAPLSSTTKGGASAAEKTTEDQPSSHNVKTD
PSAEDKPGPSPFSS---DQPEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEAAGLESQRRKRKKTKGDAPNP------NPEPVPRLEREPGSEQSCPEPR-A
PAPPDREHAAQAREGGPQDSHGDTD

---------------------------------MIMKIQKKEKQLSNLKVLSHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASQCLPQKDLYAVEE-----------EADTLFS
RKMTSHNGMENSGGGGTGVKKKRKKKDPGEQECAAKGSRDREPKPKRKREPKEPKEPKKT
KEPRKAKE---PKEPKQKDGAKKTRKPREASGTKEAKEKRGSADSIVRTKSRKT-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLPNSSLRSPEECTESTDSQXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASKMVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 453)

KQAQMKHI
FTEXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00385 // ENSGT00760000119067_8_Domain_1 (453, 488)

EVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQVLPEITHMERPASDAWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMSLEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTE-QVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPDASDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAXXXXXXXXXXXXXWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DRAFEGTPARELEVPLPDIDYLEIPVDWWDTEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTEGTTDIPERVNTDKEDNAEDKLDSLQKQMESSSDG--
-------GDGIFGEKKDDNRAAQDGSDPDKPPWPVSSALTARLRRLVTIYQRCNRKE-PC
RPEILGPSNKGYWVQEEMFKRSSEMDFINKEAQKRWTRREQADFYRTVSSFGVIYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPMWKDGXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLTYTQISRTSE
S--DNEENLVKTESR-DDYLGHPGGSLPEMVCENFISKVQDIISINHDESLFPESLENMI
YGKKVLSREPGPFRDSPNS-TN--TESRKDAVVISASKDGNCQSGGHEAEIASVPS-FMG
SLEA-GVAQMNNKNGSHLLMSLS-KERELCCSEAGQKPESIKL-------LE-SRCMAS-
--PSLSQGNESGFV--DMYNLGVC--DSRRNLSSNQQLIDLLENRSLESKLILSQNHSDE
EEEEEENEEE-----------NVDMAAGMRERPGILHLTEPSTNIPRE-----------K
SQGLHIDETK-----KGSL-------EVVSQNPGPGRAFP-QAACQCHCRHMG-------
----------RWKHSI-EKD--DIEVEKLKS----YNPNLYKSKITSM---TMEGEPIAI
PSEPYKVKHELLK-EPWKERAEEK--KGFPTY----PLEGSELKS-ENLDFE-AKDDYDR
DGNCHGQDYLGKYSEEESKSSTSGITGDTGDDLQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSGQ-QYEPSGTL-PTPVLSSTAGSRNSFPEPEASEHSFSNG
TALVAQIQK---------------------------------------------------
------------------------------------------------------------
--------------T-RRRRGRRKHVEGGRDFIFLKEPSLQAGILEVH------EDPGQA
ALSS-THSERPMPAASAPETGIAAGTRAEKDIPSKSLLDWLRQQS-DYSLEVPGFGTNFS
DKPKQKRPRCKEPGKLDINSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPAITKEPGP------------------------
-----------RGFLPENKFNHTLPEPVLRD--AGP-RRRGRRPRNDL-KAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPASFATMPTGEDVKSTLSMLPMM
LPGMATVPQMFGVGGLLNTPMATTCTSTAPASLSSTTKSGTSATEKTAEDKPSSRDIKMD
SLTEDKPDPSPFS----DQSEPAITPSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
SMQQARHSEVVGLENQKRKKKKTKGDNLNP------NPEPAPRSEKEPGSDQNCSEPS-A
PLPPDREHVAQAGEWGLKDSNNDTN

---------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDVASHCLPQKDLYTAEE-----------EAATLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKA
KEPKKAKE---HKEPKQKDGVKKVRKPREASGTKEAKEKRSCTDSAARTKSRKA-SKEQG
PTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--IIVFFLASKTVQ-EV
H----

PF00385 // ENSGT00760000119067_8_Domain_0 (366, 412)

PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYV

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEH----GTSDIPERGNTDKEDNAEDKVDGLQKQMESSSDG--
-------GDGIFGEKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGSQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEER
AARTLYRIELLRKVREQVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDTQAPGNLCCLYQTNSKLYESLTYTQMSRTSE
SLENEPENLVKVESR-DDHLSL-----PDVTCENFISKVQDVISINHDESLLPESLESMM
YGKKVLSQEPGSFRESPS--TN--TECRKDVITISISKDGNCQPGGHEAEIASGPT-FMG
SLEAGGVAQANIKNGKHLLMSIS-KEEDLCFSEAGQRPESI-------SQLE-AKCLAS-
--PSLNPGNESGFV--DMCSLSVC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAMAVGMGERPEVLHLTEPTIDIS--------R---EK
NQGFHADETK------------KGSLEVANQTPGLQRAFPPPAACQCHCKHME-------
----------RWMHGL-ESD--EFEIEKPKA----YIPDLFKSKTSTIA-M--EGEPTAV
ASEPFKVKHELLK-EPWKEGAEGQ--KVFPTY----PLEGSELKA-EDMDFENKDE-YDR
DGNCHSQDYPGKYSEEESKSSTSGIAGDIGDELQEARAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGTL-PTPVLTSSVGSRTSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARGLEQFSATHGHTPIILNGWH
GESAMDLSCSSEGSP-GATSPFPVSTSTPKIGAIS--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-THPEGPGPTTSAPEPATAASSQAEKAIPSKSLLDWLRQQA-DYSLEVPSFGANFS
DKPKQRRPRCKEPGKLDVSSLSGEERVPAVPKEPGL------------------------
-----------RGFLPENKFNHTLGEPVLRD--TGP-RRRGRRPRSELLKAPSIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAGDKPSSHDVKTD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQARHSEIVGLESQKRKKKKTKGDNPNS------HPEPAPSCEREPSSDENCAEPS-A
LLPAEREHVAQAGEGALKDSNNNTN

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-----------------ERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFNW

PF00176 // ENSGT00760000119067_8_Domain_2 (536, 811)

YNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 965)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQTEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLSDKARRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
DKAFEGTPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNTDKEDNAEDKLDGPQKQTESSSEG--
-------GDGIFGEKKDDSRAAQDGSDPDRSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWIQEEMFRRTTEMDLINKEVQKRWTRREQADFYRTVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDGGTPDATIYVEPITEER
AARTLYRIELLRKVREHVLKCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGL
NRTDCYIMNDPQLSFLDAYRNYAQHKRSDVQAPGSLCCLYQTNSKLYDSLTYTQMRRTSE
SLENEPENLVKEEGR-DDHLSL-----PDMTCENFISKVQDVISINHDESLLPESLESVI
YGKKVLSRESGSFQDIPN--TS--AESRKDTIAISASKDRSCRSGDHEAEIASGSS-FMS
SLEA-GVAQMSIQNGKHLLMSFS-KEGELCCSEAGQRPESI-------EQLE-AKCLPS-
--PSLDPGNESGFV--DMCNLSIC--DSKRNLSSDQQLIDLLENKSLESKLILSQNHSDE
EEE-EEENE----------EENLAVATGMREKTGVLHLTEPTTNIL--------R---EK
SRVFHVDETK------------KGSLEAASQTAGPQKTFP-PATCQCHCKHME-------
----------RWTHGL-END--EFEVAKSKA----YNPDLYKSKTNNITTM--EDEPTAI
PSEPFKVKHELLK-EPWKESIDGK--KGFPMY----PLEGSELKS-EDMDFENKDD-YDR
DGNCHSQEYQGKYSEEESKSSTSGIVGDIGDDLQEVRAPTIAQLLQEKTLYSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSDTL-PTPALTSSTGSRNSLSEPEAAEHSFSNG
AALAAQIQKESFLAPVFAKDEQKHRRPYEFEVER-DAKGRSLEQFSASHGHPPIVLNGWH
GESAIDLSCSSEGSP-GATSPFPVSTSTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGNLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
TLST-AHPEGPGSAPSVPEPAAAAGSPAEKAVPSKSLLDWLRQQA-DYSLEVPSFGANFS
DKPKQRRPRCKEPGKLDISSLSGEERVPAVSKEPGL------------------------
-----------RGFLPENKFNHTLPEPVLRD--SGP-RRRGRRPRSELLKAPTIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMAAVPQMFGVGGLLNTPMATTCTSTAPASLSSTTKSGSAPTEKNAEDKLSSHDVKTD
TLTEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGMGMALP
AMQQTRHSEIVGLESQKRKKKKTKGDSPNP------NPEPAPGCEREPGGDQNCAESS-T
LLPPEREHVTQPGEGALKDSNSDIN

-----------------------------------MCFFFSLSQLSKLKSLSHSPMSDAS
VNFDYKSPSPFDCSTDQEEKI---EDIANHCLSQKDLYATEE-----------EADTLFS
RKLISHNGMEDSGGRGTGVKKKRKKKDPGEQEGT-KGSKDREPKPKRKREPKEPKEPRRA
KEPKRAKE---PKEAKQKDGVKKPRKPREASGTKEAKEKRSCTDYVSRTKSKKA-SKEQG
PTPVERKKKGKRKNETTVESLELDQSLPNSTLRSPEEPTESTDSQKRRSGRQVKRRRYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN--

PF00385 // ENSGT00760000119067_8_Domain_0 (346, 412)

IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFR

ENSGT00760000119067_8_Linker_0_1 (412, 435)

NKQAQMKHI
FTEPDEDLFNPDYI

PF00385 // ENSGT00760000119067_8_Domain_1 (435, 487)

EIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFE

ENSGT00760000119067_8_Linker_1_2 (487, 534)

SLQVLPEVKHVERPASDAWQKLETSREYKNSNRLREYQLEGMNWLLF

PF00176 // ENSGT00760000119067_8_Domain_2 (534, 811)

NWYNRKN
CILADEMGLGKTIQSITFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 847)

ING--AEEKILEDFRKAHSSEASDFQLQAM
IQAAGK

PF00271 // ENSGT00760000119067_8_Domain_4 (847, 960)

LVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-EDYLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQVTIR
MIALCVSCP----------DFQDVMTDVA-------------------------------
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---------------------------------MIMKIQKKEKQLSNLKVLNHSPMSDAS
VNFDYKSPSPFDRSTDQEEKI---EDVASHCLPQKDLYAAEE-----------EAETLFP
RKMTSHNGMEDSGGGGTGVKKKRKKKDPGEQEGTAKGSKDREPKPKRKREPREPKEPRKA
KEPKRAKE---PKEPKPKDGAKKARKPREASGTKEAKEKRSSADSIARTKSKKA-SKEQG
PTPVERKKKGKRKSDTTVESLELDQGLPNSSLRSPEESTESTDSQKRRSGRQVKRRKYNE
DLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN-

PF00385 // ENSGT00760000119067_8_Domain_0 (345, 413)

-IIEKILASKTVQ-EV
H----PGEPPFDLELFYVKYRNFSYLHCKWATM-EELEKDPRIAQKIKRFRN

ENSGT00760000119067_8_Linker_0_1 (413, 434)

KQAQMKHI
FTEPDEDLFNPDY

PF00385 // ENSGT00760000119067_8_Domain_1 (434, 488)

VEVDRVLEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPA
KVKEFES

ENSGT00760000119067_8_Linker_1_2 (488, 523)

LQVLPEIKHVERPASDSWQKLEKSREYKNSNQLRE

PF00176 // ENSGT00760000119067_8_Domain_2 (523, 811)

YQLEGMNWLLFNWYNRKN
CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHG
SQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAH
RLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGD
LKTEEQVKKLQSILKPMMLRRLKDDV-EKNLAPKQETIIEVELTNIQKKYYRAILEKNFS
FLTKGANQHNMPNLINTMMELRKCCNHPYL

ENSGT00760000119067_8_Linker_2_4 (811, 881)

ING--AEEKILEDFRKTHSPDAPDFQLQAM
IQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL-ED

PF00271 // ENSGT00760000119067_8_Domain_4 (881, 965)

YLIQRRYTYERIDGRVRGN-
--LRQAAIDRFCKPDSDRFVFLLCTR--AGGLGINLTAADTCIIFDSDWNPQNDLQAQAR
CHRI

ENSGT00760000119067_8_Linker_4_5 (965, 2602)

GQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSTNGVQQLSKMEV
EDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGST--FAKASFVASG
NRTDISLDDPNFWQKWAKIAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEEDELMEFSE
LDSDSDERPTRSRRLNDKTRRYLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDM
EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQNHSGLSAPVPRGRKGKKTK
NQLLLPELKNADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLYY-LKAEILGE-AA
EKAFEGTPARELEVPLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRAD--PAL
CFLE--KVGMPDEKSLSAEQGVTDGTSDIPERGNMDKEDNTEDKLDGLQKQVESSSDG--
-------GDGIFGEKKDDGRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-LC
RPEILGPGNQGYWVQEEMFRRTSEMDLINKEAQKRWTRREQADFYRAVSSFGVVYDQEKK
TFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRSVCRLPTWKGGGPPDPSIYVEPITEER
AARTLYRIELLRKVREQVLRCPQ-LHERLQLCRPSLYLPVWWECGKHDRDLLVGTAKHGL
NRTDYYIMTDPQLSFLDAYRNYAQHKRPDTQAPESLCCLYQTNSKLYESLTYTQMSRTSE
PLENEPENLVKIEGR-DDHPTPPGASLSDMTCENFISKVQDVISITHDESLLPESLEGMM
YGKKPLSQEPGSFQESPT--TR--TEPRKDALAISANEDGNCQPGGREAEIPAGPS-FMG
SLEA-GVAQMNIKNGKHLLLSLS-GEGELC-SETGPRPESI-------GQLE-AKCLAS-
--PSLDQGNESGFV--DMCNLSVC--DSRRSLSSDHQLIDLLENKSLESKLVLSQNHSDE
EEEE-EENE----------EENVGVAAGLRERPKVVHLAEPT------ADIL--R---EK
SRDLPVEEAK------------RGSLEAVSQNPGPQGAFP-QAACQCHCKHTE-------
----------RWTRGL-ENE--EFEVEKSKG----YNPDVYRSKTNSIT-V--EGEATTA
PAEPSQGKHELSK-APWKDSAEGK--KGLPVY----P-EASELKS-EDMDFESKDD-YDR
DGNGHAQDYPGKYSEEESKSSTSGVAGDLGDDLQEARAPTIAQLLQEKTLFSFSEWPKDR
VIINRLDNICHVVLKGKWPSSQ-QYEPSGAL-PAPVLSSSAGSRSSLSEPEASEHGFSSS
AALVAQIQKESFLAPVFTKDEQKHRRPYEFEVER-DAKARSLEQFSAAHGHPPIVLNGWH
GESAIDLSCTSEGSP-GATSPFPVSASTPKIGAIG--SLQGALGMDLSGILQAGLIHPVT
GQIVNGSLRRDDAAT-RRRRGRRKHVEGGMDLIFLKEQTLQAGILEVH------EDPGQA
PPSTEH-PEGPVPASSAPEPAPAAGSQAEKAIPSKSLLDWLRQQA-DYSLEVPGFGTNFS
DKPKQRRPRCKEPGKLDVNSL

PF07533 // ENSGT00760000119067_8_Domain_5 (2602, 2680)

SGEERVPTVPKEPGL------------------------
-----------RGFLPENKFNHALAEPVLRD--AGP-RRRGRRPRSELLKAPAIV-ADSP
SGMGPLFMNGLIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLSMLPMM
LPGMATVPQMFGVGGLLNAPMATTCTSPAPAPLSSTTKSGTSATEKTVEDKPSSHDVKAD
TLAEDKPGPGPFS----DQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLSPGIGMALP
AMQQARHSEVIGLESQKRKKKKTKGDSLNP------NPEPAPGSEKEPGSDQNCPESR-A
PGPPDREHAAQAREGGLKDSNSDTN